# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- VWA_2 PF13519.6 RKO98189.1 - 0.017 15.8 0.0 0.036 14.7 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain AF-4 PF05110.13 RKO98191.1 - 2.1 6.3 4.3 2.7 5.9 4.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RVP_2 PF08284.11 RKO98193.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RKO98193.1 - 0.14 12.7 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 RKO98195.1 - 3.6e-12 46.1 0.0 3.9e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Lambda_CIII PF02061.16 RKO98195.1 - 0.043 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Lambda Phage CIII RVP_2 PF08284.11 RKO98196.1 - 0.0083 15.9 0.0 0.0085 15.9 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RKO98196.1 - 0.099 13.2 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Homeodomain PF00046.29 RKO98198.1 - 1.4e-27 95.3 11.9 2e-09 37.2 0.1 3.2 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 RKO98198.1 - 0.0033 17.3 1.9 6.2 6.8 0.1 3.6 3 0 0 3 3 3 2 Homeobox KN domain DNA_meth_N PF18284.1 RKO98198.1 - 0.0092 15.9 5.8 1.7 8.6 0.0 3.4 3 0 0 3 3 3 2 DNA methylase N-terminal domain Gag_p19 PF02228.16 RKO98198.1 - 0.17 12.4 0.1 0.82 10.2 0.1 2.1 3 0 0 3 3 3 0 Major core protein p19 Homez PF11569.8 RKO98198.1 - 0.79 9.2 4.3 9.1 5.8 0.1 2.9 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez PUA PF01472.20 RKO98201.1 - 0.00057 19.8 0.7 0.0013 18.6 0.7 1.6 1 0 0 1 1 1 1 PUA domain DegV PF02645.16 RKO98201.1 - 0.19 11.1 1.0 0.26 10.6 1.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 Prim-Pol PF09250.11 RKO98202.1 - 3.3e-15 56.8 0.0 4.6e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal DUF4715 PF15835.5 RKO98203.1 - 0.075 13.1 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) DUF4874 PF16173.5 RKO98203.1 - 0.075 12.7 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Not3 PF04065.15 RKO98203.1 - 0.44 10.0 5.3 0.12 11.8 0.4 2.3 2 2 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Uds1 PF15456.6 RKO98203.1 - 2.1 8.5 9.5 0.34 11.1 3.4 2.8 1 1 1 2 2 2 0 Up-regulated During Septation PTPA PF03095.15 RKO98204.1 - 3.7e-67 226.9 0.0 4.3e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein CCD48 PF15799.5 RKO98204.1 - 0.28 9.5 4.7 0.46 8.7 4.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 HR1 PF02185.16 RKO98205.1 - 4.2e-09 36.4 0.2 5.7e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 Hr1 repeat HSP20 PF00011.21 RKO98207.1 - 1.3e-06 28.5 0.0 1.3e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family VWA_2 PF13519.6 RKO98208.1 - 0.1 13.3 0.0 0.58 10.8 0.0 2.3 2 1 0 2 2 2 0 von Willebrand factor type A domain UQ_con PF00179.26 RKO98211.1 - 9e-09 35.1 0.0 9.7e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DASH_Dad2 PF08654.10 RKO98212.1 - 0.44 11.0 2.4 47 4.5 0.1 3.2 1 1 2 3 3 3 0 DASH complex subunit Dad2 Sel_put PF04328.13 RKO98215.1 - 0.11 12.6 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Selenoprotein, putative Nop14 PF04147.12 RKO98216.1 - 2.6 6.2 5.3 2.7 6.1 5.3 1.0 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.23 RKO98218.1 - 3.3e-05 23.7 2.0 3.3e-05 23.7 2.0 2.0 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 RKO98218.1 - 0.0081 16.4 0.0 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein AZUL PF16558.5 RKO98218.1 - 0.42 10.9 3.9 0.28 11.5 0.5 2.3 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Mito_carr PF00153.27 RKO98219.1 - 3.6e-56 187.1 0.1 1.1e-18 67.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CARD_2 PF16739.5 RKO98220.1 - 0.15 12.1 0.0 8.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Caspase recruitment domain Tubulin PF00091.25 RKO98221.1 - 3.3e-28 99.2 0.0 3.7e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 RKO98221.1 - 8.9e-07 29.2 0.0 1.3e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Pkinase PF00069.25 RKO98222.1 - 2.6e-34 118.8 0.0 3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98222.1 - 6.8e-10 38.7 0.0 8.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO98222.1 - 0.014 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO98222.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RKO98222.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3498 PF12004.8 RKO98223.1 - 0.035 13.3 0.1 0.035 13.3 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3498) zf-RVT PF13966.6 RKO98225.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Chalcone_2 PF16035.5 RKO98227.1 - 6.7e-06 26.0 0.0 8.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 RKO98227.1 - 0.022 14.9 0.1 0.036 14.2 0.1 1.3 1 0 0 1 1 1 0 Chalcone isomerase-like DUF1658 PF07871.11 RKO98227.1 - 0.15 12.0 0.9 0.45 10.5 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) Glycos_transf_2 PF00535.26 RKO98228.1 - 0.0023 17.8 0.0 0.0081 16.0 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RKO98228.1 - 0.0027 17.6 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Galactosyl_T PF01762.21 RKO98228.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase Cyt-b5 PF00173.28 RKO98229.1 - 2.7e-15 56.3 0.0 2.9e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4404 PF14357.6 RKO98229.1 - 0.13 12.9 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Noc2 PF03715.13 RKO98232.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Noc2p family DUF2150 PF09920.9 RKO98232.1 - 0.24 11.4 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) Utp14 PF04615.13 RKO98234.1 - 2.4 6.6 10.2 2.3 6.7 10.2 1.0 1 0 0 1 1 1 0 Utp14 protein Membralin PF09746.9 RKO98234.1 - 9.8 5.1 8.5 12 4.8 8.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Sigma70_ner PF04546.13 RKO98235.1 - 0.025 14.5 0.1 0.11 12.4 0.0 2.1 2 1 0 2 2 2 0 Sigma-70, non-essential region DUF4715 PF15835.5 RKO98235.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Not3 PF04065.15 RKO98235.1 - 0.11 11.9 6.3 0.028 13.9 0.9 2.4 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Fer2_BFD PF04324.15 RKO98237.1 - 0.092 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Helicase_C PF00271.31 RKO98238.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF5451 PF17532.2 RKO98238.1 - 6 7.1 9.7 0.76 10.0 5.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5451) VWA_2 PF13519.6 RKO98239.1 - 0.0016 19.1 0.0 0.0016 19.1 0.0 3.0 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF3473 PF11959.8 RKO98239.1 - 0.091 12.8 0.1 37 4.3 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3473) TFIIA PF03153.13 RKO98239.1 - 1.7 8.5 14.1 3.1 7.7 14.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serglycin PF04360.12 RKO98243.1 - 0.047 13.6 2.6 0.19 11.7 2.6 1.8 1 1 0 1 1 1 0 Serglycin DUF515 PF04415.12 RKO98243.1 - 0.066 11.6 0.2 0.081 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) NAPRTase PF04095.16 RKO98244.1 - 1e-05 25.3 0.0 1.1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RRP36 PF06102.12 RKO98246.1 - 2.6 8.0 4.7 0.58 10.1 0.3 2.0 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 RVP_2 PF08284.11 RKO98247.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease AhpC-TSA PF00578.21 RKO98248.1 - 1.8e-30 105.4 0.0 2.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO98248.1 - 2e-13 50.3 0.0 2.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RKO98248.1 - 3.9e-07 29.8 0.0 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PTS_EIIC PF02378.18 RKO98250.1 - 0.00026 20.1 0.4 0.00028 20.0 0.4 1.1 1 0 0 1 1 1 1 Phosphotransferase system, EIIC VWA_2 PF13519.6 RKO98251.1 - 2.5e-05 24.8 0.0 3.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RKO98251.1 - 0.00018 21.8 0.0 0.00024 21.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain SNAP-25 PF00835.19 RKO98251.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 SNAP-25 family Abhydrolase_6 PF12697.7 RKO98253.1 - 4.9e-14 53.5 13.6 4.9e-14 53.5 13.6 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RKO98253.1 - 6.6e-11 41.9 2.7 3.1e-10 39.7 2.7 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKO98253.1 - 3.4e-08 33.4 0.1 5.6e-07 29.5 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 RKO98253.1 - 0.00033 20.3 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 RKO98253.1 - 0.0024 18.0 0.3 0.051 13.7 0.3 2.5 1 1 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.13 RKO98253.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold HSP20 PF00011.21 RKO98254.1 - 8.1e-06 25.9 0.0 1e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Calici_MSP PF05752.11 RKO98255.1 - 0.097 12.5 0.2 0.27 11.0 0.2 1.7 1 0 0 1 1 1 0 Calicivirus minor structural protein TPR_6 PF13174.6 RKO98256.1 - 0.0032 18.0 5.5 3.6 8.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO98256.1 - 0.0059 17.3 19.7 0.61 11.1 0.4 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKO98256.1 - 0.0093 16.5 14.8 0.12 13.0 2.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ArgJ PF01960.18 RKO98256.1 - 0.021 13.6 0.2 0.033 12.9 0.2 1.3 1 0 0 1 1 1 0 ArgJ family TPR_17 PF13431.6 RKO98256.1 - 3.3 8.3 5.2 13 6.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat KASH_CCD PF14662.6 RKO98257.1 - 0.0068 16.3 16.5 0.0068 16.3 16.5 4.1 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH DUF4250 PF14056.6 RKO98257.1 - 0.25 11.3 0.8 11 6.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) DASH_Dad1 PF08649.10 RKO98257.1 - 0.8 9.9 4.8 0.41 10.9 0.8 2.7 4 0 0 4 4 4 0 DASH complex subunit Dad1 DUF1664 PF07889.12 RKO98257.1 - 0.87 9.6 44.3 0.21 11.6 3.8 6.1 1 1 3 6 6 6 0 Protein of unknown function (DUF1664) Filament PF00038.21 RKO98257.1 - 1.4 8.5 64.5 1.1 8.8 12.6 3.8 1 1 1 3 3 3 0 Intermediate filament protein Shugoshin_N PF07558.11 RKO98257.1 - 2.2 8.2 5.9 5.9 6.8 0.5 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region GAS PF13851.6 RKO98257.1 - 2.8 7.3 63.6 0.65 9.3 5.8 5.3 1 1 5 6 6 6 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 RKO98257.1 - 4.9 7.2 60.0 0.048 13.8 7.8 4.3 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 RKO98257.1 - 7.1 5.4 64.6 0.033 13.1 17.5 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein XhlA PF10779.9 RKO98257.1 - 9 6.6 20.3 0.63 10.3 1.0 5.2 5 0 0 5 5 5 0 Haemolysin XhlA zf-C2H2_4 PF13894.6 RKO98258.1 - 0.006 17.3 0.1 0.32 11.9 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO98258.1 - 0.0068 16.8 0.1 0.41 11.2 0.0 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 RKO98258.1 - 0.62 10.4 1.9 8.1 6.8 0.1 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pas_Saposin PF09016.10 RKO98262.1 - 0.15 12.4 0.6 0.29 11.5 0.1 1.7 2 0 0 2 2 2 0 Pas factor saposin fold DAO PF01266.24 RKO98263.1 - 0.0063 16.1 0.0 0.0099 15.5 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FlgN PF05130.12 RKO98265.1 - 0.015 15.8 0.8 0.02 15.4 0.8 1.4 1 1 0 1 1 1 0 FlgN protein SDH_C PF18317.1 RKO98266.1 - 0.04 13.7 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Holin_9 PF16936.5 RKO98267.1 - 0.078 13.2 0.1 0.091 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative holin Retrotran_gag_2 PF14223.6 RKO98268.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 RKO98268.1 - 8.7e-05 22.1 0.1 0.0022 17.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 RKO98268.1 - 0.0017 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Tctex-1 PF03645.13 RKO98269.1 - 3.5e-22 78.6 0.0 4.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family FKS1_dom1 PF14288.6 RKO98270.1 - 0.0025 18.1 0.2 11 6.4 0.1 3.5 3 0 0 3 3 3 2 1,3-beta-glucan synthase subunit FKS1, domain-1 CCDC24 PF15669.5 RKO98270.1 - 0.037 13.9 9.6 0.51 10.2 0.6 3.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 24 family Glyco_tranf_2_3 PF13641.6 RKO98271.1 - 0.013 15.4 0.1 0.054 13.4 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Rho_GDI PF02115.17 RKO98273.1 - 1.1e-58 198.2 0.0 1.2e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Reticulon PF02453.17 RKO98274.1 - 7.9e-21 74.6 0.3 9.7e-21 74.4 0.3 1.1 1 0 0 1 1 1 1 Reticulon Mon1 PF03164.14 RKO98275.1 - 8.1e-17 61.4 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Imm5 PF14423.6 RKO98275.1 - 0.61 10.3 1.4 1.1 9.4 1.4 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 SR-25 PF10500.9 RKO98275.1 - 0.79 9.3 3.4 1.2 8.7 3.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1656 PF07869.12 RKO98275.1 - 3.5 7.7 5.8 14 5.7 5.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF1769 PF08588.10 RKO98277.1 - 1.1e-19 70.3 0.3 2.4e-19 69.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MAPEG PF01124.18 RKO98278.1 - 6.4e-09 35.8 2.4 9.2e-09 35.3 2.4 1.3 1 1 0 1 1 1 1 MAPEG family DUF737 PF05300.11 RKO98279.1 - 0.023 15.1 2.7 0.033 14.5 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2407_C PF13373.6 RKO98279.1 - 0.049 13.8 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain FYDLN_acid PF09538.10 RKO98279.1 - 0.05 14.3 4.6 0.065 13.9 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TEX13 PF15186.6 RKO98279.1 - 1.2 8.8 5.8 2.1 8.0 5.8 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF2514 PF10721.9 RKO98279.1 - 4.1 7.4 17.6 9.1 6.3 17.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Vps36_ESCRT-II PF11605.8 RKO98281.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.6 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 CRAL_TRIO PF00650.20 RKO98282.1 - 1.2e-32 112.9 0.1 1.3e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RKO98282.1 - 0.00051 20.2 0.0 0.00065 19.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF5478 PF17572.2 RKO98282.1 - 0.087 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5478) SRA1 PF07304.11 RKO98285.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 2.3 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 RKO98285.1 - 0.11 12.6 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Prp18 domain SUIM_assoc PF16619.5 RKO98285.1 - 5.4 7.2 9.1 13 5.9 9.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3498 PF12004.8 RKO98286.1 - 0.45 9.6 8.8 0.5 9.5 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) SR-25 PF10500.9 RKO98286.1 - 3.5 7.2 12.1 4 7.0 12.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acyltransferase PF01553.21 RKO98289.1 - 2.6e-23 82.1 0.0 3.8e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RKO98289.1 - 4.3e-10 39.5 0.0 7.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus ATP-grasp_2 PF08442.10 RKO98290.1 - 3.7e-73 245.4 0.6 4.9e-73 245.0 0.6 1.1 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 RKO98290.1 - 2.3e-07 30.5 0.4 4.6e-07 29.5 0.4 1.4 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 RKO98290.1 - 0.0061 16.4 0.2 0.093 12.5 0.0 2.2 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DEAD PF00270.29 RKO98291.1 - 9.9e-49 165.5 0.0 4.2e-48 163.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98291.1 - 5.5e-32 110.4 0.0 1.8e-31 108.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98291.1 - 0.0041 17.2 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 RKO98291.1 - 0.028 13.2 0.0 0.4 9.4 0.0 2.2 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 RKO98291.1 - 0.044 14.1 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4766 PF15973.5 RKO98291.1 - 0.5 11.0 18.9 0.14 12.7 8.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) RhoGAP PF00620.27 RKO98292.1 - 2.5e-05 24.1 0.0 5.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 RKO98292.1 - 0.0044 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 RKO98292.1 - 0.0069 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Fz PF01392.22 RKO98295.1 - 1.1e-06 29.2 7.5 3e-06 27.8 7.1 2.0 1 1 1 2 2 2 1 Fz domain Abhydrolase_9_N PF15420.6 RKO98295.1 - 1.4 8.9 8.5 3.6 7.5 8.5 1.7 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus TMEM132D_C PF15706.5 RKO98296.1 - 0.18 11.6 1.0 0.44 10.3 1.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Get5_C PF18514.1 RKO98298.1 - 0.00091 18.9 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 2 Get5 C-terminal domain Ras PF00071.22 RKO98302.1 - 1.3e-54 184.2 0.0 1.5e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO98302.1 - 1.2e-21 77.1 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO98302.1 - 2e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RKO98302.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKO98302.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PP1c_bdg PF10488.9 RKO98305.1 - 0.04 13.4 2.5 0.053 13.0 2.5 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Peptidase_C27 PF05407.12 RKO98305.1 - 0.072 13.2 8.0 0.1 12.7 8.0 1.2 1 0 0 1 1 1 0 Rubella virus endopeptidase Vps36_ESCRT-II PF11605.8 RKO98306.1 - 1.1e-14 54.4 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 RKO98306.1 - 0.078 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Vps36-NZF-N PF16988.5 RKO98306.1 - 1.6 8.1 7.1 12 5.4 7.1 2.1 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain O-FucT PF10250.9 RKO98307.1 - 0.049 13.3 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase SHMT PF00464.19 RKO98308.1 - 2e-165 550.3 0.0 2.5e-165 549.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase LPMO_10 PF03067.15 RKO98309.1 - 1.2e-10 42.3 1.5 3.2e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RKO98309.1 - 0.0042 17.0 0.7 0.015 15.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 RKO98309.1 - 6.3 5.9 24.2 10 5.2 24.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein CEND1 PF15677.5 RKO98310.1 - 1.9 9.0 5.3 0.34 11.5 0.2 2.2 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 EF-hand_7 PF13499.6 RKO98311.1 - 6e-22 77.9 1.3 2e-12 47.4 0.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RKO98311.1 - 2.3e-21 73.7 4.8 0.00052 19.4 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RKO98311.1 - 2e-16 59.5 5.8 0.00023 20.9 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RKO98311.1 - 5.8e-16 57.0 8.5 0.003 17.3 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RKO98311.1 - 1.5e-13 49.5 4.9 0.0022 17.4 0.0 4.2 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 RKO98311.1 - 0.0064 16.8 0.7 0.34 11.2 0.3 2.7 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RKO98311.1 - 0.036 14.0 2.9 5.7 6.9 1.8 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Pyridoxal_deC PF00282.19 RKO98312.1 - 1.1e-17 63.9 0.0 1.7e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RKO98312.1 - 3.2e-07 29.7 0.0 8.3e-07 28.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RKO98312.1 - 0.00011 21.7 0.2 0.00018 20.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family RVT_N PF13655.6 RKO98312.1 - 0.043 14.1 0.3 0.15 12.3 0.3 1.9 1 1 0 1 1 1 0 N-terminal domain of reverse transcriptase Lon_C PF05362.13 RKO98313.1 - 7.3e-55 185.7 0.0 7.9e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 RKO98313.1 - 8.7e-07 28.8 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase ssDBP PF17878.1 RKO98313.1 - 0.047 13.9 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein Birna_VP4 PF01768.16 RKO98313.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Birnavirus VP4 protein C2 PF00168.30 RKO98315.1 - 4.1e-25 88.1 0.0 1.3e-12 47.9 0.0 3.8 3 0 0 3 3 3 3 C2 domain Membr_traf_MHD PF10540.9 RKO98315.1 - 2.6e-12 47.2 0.5 8.7e-05 22.7 0.0 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 RKO98315.1 - 0.015 13.8 0.8 0.024 13.2 0.8 1.2 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Exo_endo_phos PF03372.23 RKO98316.1 - 9.8e-06 25.2 1.2 2.2e-05 24.1 1.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ldh_1_C PF02866.18 RKO98317.1 - 4.8e-49 166.5 0.2 7.8e-49 165.8 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RKO98317.1 - 4.7e-46 156.4 0.4 9.4e-46 155.4 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 RKO98317.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 RKO98317.1 - 0.12 12.0 1.9 3.8 7.0 0.1 2.7 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Smr PF01713.21 RKO98318.1 - 1.9e-06 28.1 0.0 9.9e-06 25.8 0.0 2.3 1 0 0 1 1 1 1 Smr domain TFIIA PF03153.13 RKO98318.1 - 0.11 12.5 5.0 0.44 10.5 5.0 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bVLRF1 PF18826.1 RKO98319.1 - 6.3e-52 175.4 0.0 1.2e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_3 PF13606.6 RKO98319.1 - 0.00061 20.0 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 RKO98319.1 - 0.0015 18.8 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKO98319.1 - 0.032 14.8 0.0 0.074 13.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 RKO98319.1 - 0.067 13.7 0.2 0.2 12.1 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeat C2 PF00168.30 RKO98320.1 - 2.3e-21 76.0 0.0 6.4e-08 32.8 0.0 3.5 3 0 0 3 3 3 3 C2 domain DUF810 PF05664.11 RKO98320.1 - 0.017 13.7 0.8 0.026 13.1 0.8 1.2 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Cu-oxidase PF00394.22 RKO98321.1 - 2.7e-34 118.6 0.0 5.8e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RKO98321.1 - 8.2e-27 93.6 9.4 2.3e-23 82.4 2.6 4.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RKO98321.1 - 8.9e-27 93.5 2.0 7.1e-26 90.6 0.1 3.2 4 1 0 4 4 4 1 Multicopper oxidase ERCC3_RAD25_C PF16203.5 RKO98322.1 - 1.1e-103 345.7 0.0 2.1e-103 344.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 RKO98322.1 - 7.7e-35 119.8 0.3 2.5e-34 118.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98322.1 - 1.5e-16 60.8 0.0 3.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO98322.1 - 2e-11 44.2 1.1 4.3e-11 43.1 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 RKO98322.1 - 1.1e-07 30.9 0.0 1.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 RKO98322.1 - 1.7e-06 27.9 0.0 3.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 RKO98322.1 - 0.0037 16.2 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 PatG_D PF18047.1 RKO98323.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 PatG Domain NAD_binding_6 PF08030.12 RKO98326.1 - 6.3e-33 114.1 0.0 1.1e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RKO98326.1 - 3.3e-22 78.6 0.0 8.4e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RKO98326.1 - 8.4e-19 67.9 11.5 1.9e-18 66.8 11.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 RKO98326.1 - 0.037 14.7 0.0 0.19 12.4 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Flavi_M PF01004.19 RKO98326.1 - 0.091 12.5 3.8 0.15 11.8 0.8 2.3 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Peptidase_U4 PF03419.13 RKO98326.1 - 1.4 8.1 9.4 0.046 13.0 2.3 2.0 1 1 1 2 2 2 0 Sporulation factor SpoIIGA HEAT PF02985.22 RKO98327.1 - 3.9e-37 123.1 35.3 0.0053 16.9 0.1 14.0 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 RKO98327.1 - 3.4e-30 104.3 30.8 5.2e-08 33.2 0.0 8.4 3 3 6 9 9 9 9 HEAT repeats Vac14_Fab1_bd PF12755.7 RKO98327.1 - 1.6e-12 47.8 3.4 0.005 17.4 0.2 7.3 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RKO98327.1 - 2.3e-08 34.2 10.6 0.095 12.7 0.1 5.6 5 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RKO98327.1 - 6.8e-08 32.9 33.5 0.003 18.0 0.1 8.5 9 3 2 11 11 11 4 HEAT-like repeat Arm PF00514.23 RKO98327.1 - 4.1e-06 26.6 16.8 0.032 14.3 0.0 7.9 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 RKO98327.1 - 1.6e-05 23.7 13.2 0.013 14.1 2.4 5.1 4 1 0 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 RKO98327.1 - 9.4e-05 22.6 2.4 5.4 7.2 0.1 4.2 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Ecm29 PF13001.7 RKO98327.1 - 0.045 12.4 2.9 5.6 5.5 0.1 3.5 3 0 0 3 3 3 0 Proteasome stabiliser DRIM PF07539.12 RKO98327.1 - 0.25 9.6 4.9 1.3 7.2 0.1 3.0 2 1 0 3 3 3 0 Down-regulated in metastasis Cohesin_HEAT PF12765.7 RKO98327.1 - 0.74 10.2 4.6 10 6.6 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF4439 PF14530.6 RKO98327.1 - 8.2 7.1 10.1 0.74 10.5 0.6 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4439) Pkinase PF00069.25 RKO98329.1 - 2.9e-49 167.8 0.0 3.5e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98329.1 - 5.6e-20 71.7 0.0 7e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO98329.1 - 4.6e-05 22.9 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO98329.1 - 0.0056 16.6 1.5 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RKO98329.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_1 PF00130.22 RKO98330.1 - 1.1e-11 44.4 5.1 2.2e-11 43.5 5.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 RKO98330.1 - 0.004 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_2 PF07653.17 RKO98330.1 - 0.055 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_16 PF18348.1 RKO98330.1 - 0.093 12.6 1.0 0.37 10.6 1.0 2.1 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain ZapB PF06005.12 RKO98330.1 - 0.19 12.2 2.0 0.31 11.5 0.0 2.2 3 0 0 3 3 3 0 Cell division protein ZapB PHD_4 PF16866.5 RKO98330.1 - 0.88 9.7 3.8 2.1 8.5 3.8 1.6 1 0 0 1 1 1 0 PHD-finger Retrotrans_gag PF03732.17 RKO98331.1 - 7.1e-05 23.0 0.0 9.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein MLVIN_C PF18697.1 RKO98332.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain COX7C PF02935.16 RKO98333.1 - 0.0032 17.7 2.5 0.0032 17.7 2.5 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc AAA PF00004.29 RKO98334.1 - 5.2e-20 72.2 0.0 5.6e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKO98334.1 - 4.7e-06 26.6 0.0 7.8e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO98334.1 - 5.8e-06 26.8 0.0 0.0004 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RKO98334.1 - 9.5e-05 22.2 0.3 0.00017 21.4 0.1 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKO98334.1 - 0.00012 22.3 0.0 0.011 16.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 RKO98334.1 - 0.00016 21.3 0.4 0.00053 19.6 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RKO98334.1 - 0.00054 20.1 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 RKO98334.1 - 0.00095 18.6 1.2 0.0026 17.2 1.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKO98334.1 - 0.00097 19.3 0.0 0.0012 19.1 0.0 1.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 RKO98334.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RKO98334.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 RKO98334.1 - 0.024 14.3 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 RKO98334.1 - 0.025 14.4 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 RKO98334.1 - 0.026 14.4 0.0 0.032 14.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKO98334.1 - 0.03 14.7 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RKO98334.1 - 0.04 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RKO98334.1 - 0.049 14.2 0.0 0.092 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RKO98334.1 - 0.087 13.2 0.2 0.13 12.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RKO98334.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 RKO98334.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 RKO98334.1 - 0.15 11.8 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 RKO98334.1 - 0.2 12.1 0.0 0.24 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKO98334.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 RKO98334.1 - 0.26 11.2 0.0 1.2 9.0 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain PAPS_reduct PF01507.19 RKO98335.1 - 4.8e-26 91.8 0.0 6.2e-19 68.7 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family A_deaminase PF00962.22 RKO98336.1 - 7.9e-125 416.5 0.0 1e-124 416.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase AAA PF00004.29 RKO98337.1 - 6.5e-43 146.3 0.0 1.4e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO98337.1 - 2.3e-12 46.5 0.1 4.6e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RKO98337.1 - 5.3e-10 39.1 0.1 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 RKO98337.1 - 3.7e-07 30.4 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKO98337.1 - 1.3e-06 28.5 0.1 2.8e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO98337.1 - 1.8e-06 28.4 0.0 0.00053 20.4 0.1 2.8 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 RKO98337.1 - 9.8e-06 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKO98337.1 - 0.00019 21.7 0.1 0.0045 17.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RKO98337.1 - 0.001 18.3 0.0 0.0025 17.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 RKO98337.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 RKO98337.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO98337.1 - 0.002 18.7 0.0 0.006 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKO98337.1 - 0.0032 16.9 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RKO98337.1 - 0.0042 17.1 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RKO98337.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RKO98337.1 - 0.007 15.6 0.2 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 RKO98337.1 - 0.0084 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKO98337.1 - 0.0091 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 RKO98337.1 - 0.011 15.8 0.0 0.031 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 RKO98337.1 - 0.011 15.4 0.1 2.4 7.8 0.0 2.7 2 1 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 RKO98337.1 - 0.012 15.0 0.4 0.044 13.1 0.0 2.0 3 0 0 3 3 3 0 KaiC IstB_IS21 PF01695.17 RKO98337.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 RKO98337.1 - 0.019 14.7 0.0 0.063 13.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4600 PF15372.6 RKO98337.1 - 0.038 14.4 1.4 0.092 13.2 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) NACHT PF05729.12 RKO98337.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 RKO98337.1 - 0.076 12.6 0.5 0.4 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RKO98337.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Med4 PF10018.9 RKO98337.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PhoH PF02562.16 RKO98337.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 RKO98337.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKO98337.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Prot_ATP_OB_N PF17758.1 RKO98337.1 - 0.15 11.7 0.2 0.37 10.5 0.0 1.7 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain AAA_11 PF13086.6 RKO98337.1 - 0.22 11.3 0.2 0.48 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain GreA_GreB_N PF03449.15 RKO98337.1 - 2.5 8.3 5.9 19 5.5 0.0 3.2 4 0 0 4 4 2 0 Transcription elongation factor, N-terminal RRM_1 PF00076.22 RKO98338.1 - 5.1e-17 61.4 0.0 7.2e-08 32.1 0.0 6.2 6 0 0 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO98338.1 - 0.054 13.6 0.1 0.45 10.7 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 RKO98338.1 - 0.13 12.3 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2574 PF10836.8 RKO98338.1 - 0.3 11.0 2.4 1.5 8.7 2.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) LSM PF01423.22 RKO98339.1 - 8.7e-18 63.8 0.1 1.1e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain PCRF PF03462.18 RKO98340.1 - 5.7e-53 179.7 0.5 9.6e-53 178.9 0.5 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 RKO98340.1 - 4.3e-33 113.7 0.1 7.5e-33 112.9 0.1 1.4 1 0 0 1 1 1 1 RF-1 domain Ecl1 PF12855.7 RKO98341.1 - 0.041 15.0 0.0 0.041 15.0 0.0 2.9 3 1 0 3 3 3 0 ECL1/2/3 zinc binding proteins RVT_1 PF00078.27 RKO98342.1 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 RKO98344.1 - 3.2e-18 65.8 9.1 2.8e-06 27.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98344.1 - 2.9e-05 24.3 0.0 0.0044 17.3 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO98344.1 - 0.093 11.4 0.1 0.91 8.1 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TMV_coat PF00721.21 RKO98346.1 - 0.005 16.7 1.7 0.0071 16.2 1.7 1.4 1 0 0 1 1 1 1 Virus coat protein (TMV like) ADIP PF11559.8 RKO98346.1 - 0.027 14.6 10.0 0.027 14.6 10.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 RKO98346.1 - 0.8 9.6 4.3 0.45 10.4 0.8 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.10 RKO98346.1 - 1.2 9.3 8.3 0.33 11.1 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 RKO98346.1 - 1.4 8.9 20.2 0.16 12.0 14.4 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 RKO98346.1 - 2.6 6.9 15.6 1.3 7.8 13.1 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3138 PF11336.8 RKO98346.1 - 3 6.4 8.9 0.06 12.0 1.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) bZIP_2 PF07716.15 RKO98346.1 - 5.3 7.2 9.0 3.9 7.6 0.0 3.5 4 0 0 4 4 4 0 Basic region leucine zipper AAA_11 PF13086.6 RKO98347.1 - 5.4e-10 39.5 0.0 5.7e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO98347.1 - 9.9e-08 32.4 0.0 1e-07 32.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO98347.1 - 3.2e-06 27.0 0.0 3.4e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKO98347.1 - 0.0043 16.6 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO98347.1 - 0.0052 17.1 0.0 0.0057 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RKO98347.1 - 0.0071 16.4 0.0 0.0076 16.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RKO98347.1 - 0.0088 16.4 0.0 0.0098 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 RKO98347.1 - 0.011 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 RKO98347.1 - 0.013 15.9 0.3 0.047 14.1 0.2 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RKO98347.1 - 0.013 15.2 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 RKO98347.1 - 0.017 15.5 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 RKO98347.1 - 0.037 14.0 0.1 0.056 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 RKO98347.1 - 0.045 13.3 0.0 0.047 13.2 0.0 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RsgA_GTPase PF03193.16 RKO98347.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase PhoH PF02562.16 RKO98347.1 - 0.074 12.5 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 RKO98347.1 - 0.094 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 RKO98347.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF2075 PF09848.9 RKO98347.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 RKO98347.1 - 0.15 12.2 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.6 RKO98347.1 - 0.21 12.1 0.0 0.26 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 RKO98348.1 - 7.4e-12 45.3 0.0 8.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RKO98349.1 - 9.8e-18 64.5 0.6 1e-17 64.4 0.6 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 RKO98349.1 - 0.00054 19.7 0.1 0.0011 18.8 0.1 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 RKO98349.1 - 0.0085 15.9 0.0 0.009 15.8 0.0 1.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 RKO98349.1 - 0.049 12.9 1.0 0.08 12.2 0.3 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 RKO98350.1 - 2e-94 313.0 0.0 7e-46 155.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO98350.1 - 2.8e-22 78.2 6.4 5.7e-11 42.0 0.9 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 RKO98350.1 - 1.4e-17 63.6 0.9 4.3e-17 62.1 0.2 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 RKO98350.1 - 9.3e-14 51.5 0.1 2.5e-05 24.1 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RKO98350.1 - 2.3e-13 50.6 0.0 7.5e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RKO98350.1 - 1.4e-11 44.8 0.0 2.1e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RKO98350.1 - 1.6e-11 44.4 0.1 3.3e-05 23.9 0.1 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO98350.1 - 3.7e-11 43.7 1.7 0.00055 20.4 0.0 4.8 3 2 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 RKO98350.1 - 1.5e-09 37.5 0.0 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 RKO98350.1 - 8.1e-09 35.9 0.3 0.061 13.6 0.1 4.1 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 RKO98350.1 - 2.1e-08 33.8 0.0 0.00091 18.5 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 RKO98350.1 - 1.5e-07 31.3 0.3 9.8e-06 25.5 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 RKO98350.1 - 2.8e-07 30.1 0.2 0.022 14.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RKO98350.1 - 4e-07 30.0 0.1 0.044 13.5 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.22 RKO98350.1 - 8.4e-07 29.3 0.0 0.0077 16.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 RKO98350.1 - 9.5e-07 28.9 0.0 0.047 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RKO98350.1 - 2e-06 28.4 0.0 0.1 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RKO98350.1 - 3.1e-06 27.5 0.2 0.074 13.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 RKO98350.1 - 4.7e-06 27.1 0.0 0.014 15.9 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 RKO98350.1 - 6.7e-06 26.1 0.0 0.074 12.9 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_7 PF12775.7 RKO98350.1 - 1.3e-05 24.8 0.0 0.066 12.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 RKO98350.1 - 2e-05 23.8 0.1 0.036 13.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 RKO98350.1 - 3e-05 24.5 0.3 0.73 10.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain ATPase PF06745.13 RKO98350.1 - 3.3e-05 23.4 1.1 2.2 7.6 0.0 3.9 4 0 0 4 4 4 2 KaiC AAA_25 PF13481.6 RKO98350.1 - 5.2e-05 22.9 2.5 1.6 8.3 0.0 4.0 2 2 1 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 RKO98350.1 - 6e-05 22.9 0.0 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 RKO98350.1 - 0.00017 21.4 0.0 0.84 9.3 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 RKO98350.1 - 0.00026 21.0 0.1 0.21 11.5 0.0 3.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 RKO98350.1 - 0.00031 20.8 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 RKO98350.1 - 0.00033 20.2 0.1 0.65 9.4 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 RKO98350.1 - 0.00046 19.4 0.0 0.076 12.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 RKO98350.1 - 0.00064 19.1 0.0 0.87 8.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 RKO98350.1 - 0.00067 19.4 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 RKO98350.1 - 0.001 18.9 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RKO98350.1 - 0.001 19.0 0.1 0.22 11.4 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 RKO98350.1 - 0.0011 19.0 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 RKO98350.1 - 0.0012 18.1 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 RKO98350.1 - 0.0015 17.8 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 RKO98350.1 - 0.0053 16.6 0.0 4 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 RKO98350.1 - 0.0065 16.6 0.0 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 RKO98350.1 - 0.0074 16.2 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 RKO98350.1 - 0.014 15.8 1.8 10 6.4 0.2 3.6 3 1 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 RKO98350.1 - 0.017 15.0 0.4 3.2 7.7 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 RKO98350.1 - 0.04 13.6 0.1 7.6 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RKO98350.1 - 0.065 13.0 0.0 16 5.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 RKO98350.1 - 0.067 13.3 0.0 9.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 RKO98350.1 - 0.1 12.4 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UFD1 PF03152.14 RKO98350.1 - 0.16 11.4 0.0 0.96 8.9 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 S4 PF01479.25 RKO98351.1 - 1.4e-12 47.1 0.1 4.8e-12 45.4 0.0 2.0 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 RKO98351.1 - 2.2e-09 38.1 0.7 3.2e-09 37.6 0.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain HSP70 PF00012.20 RKO98353.1 - 3.5e-267 887.5 14.4 4e-267 887.3 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKO98353.1 - 1.7e-13 50.1 11.5 4.6e-13 48.7 3.1 2.8 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 RKO98353.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 RKO98353.1 - 0.012 16.0 5.5 10 6.6 0.2 4.0 3 1 0 3 3 3 0 Cell division protein FtsA DUF5333 PF17267.2 RKO98353.1 - 0.027 14.6 5.6 0.39 10.9 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5333) cwf21 PF08312.12 RKO98353.1 - 0.14 12.3 3.9 0.36 11.0 2.0 2.4 2 0 0 2 2 2 0 cwf21 domain Arc_PepC PF06819.11 RKO98353.1 - 4.3 7.5 7.7 4.9 7.3 3.3 3.0 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain Sec1 PF00995.23 RKO98354.1 - 4e-05 23.1 0.0 0.00038 19.8 0.0 2.0 2 0 0 2 2 2 1 Sec1 family PhoH PF02562.16 RKO98356.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 RKO98356.1 - 0.013 15.6 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO98356.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase SRP14 PF02290.15 RKO98358.1 - 3.5e-14 52.9 0.0 6.1e-13 49.0 0.0 2.5 1 1 2 3 3 3 1 Signal recognition particle 14kD protein SRP-alpha_N PF04086.13 RKO98358.1 - 0.72 9.7 12.4 0.83 9.5 12.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LSM PF01423.22 RKO98359.1 - 3.1e-19 68.4 0.9 4.4e-19 67.9 0.9 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO98359.1 - 0.0068 16.5 0.2 0.0089 16.1 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 RKO98359.1 - 0.045 14.4 8.0 0.074 13.7 8.0 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG TMF_TATA_bd PF12325.8 RKO98360.1 - 0.0061 16.8 0.4 0.011 16.0 0.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 RKO98360.1 - 0.061 13.4 0.9 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HEAT_2 PF13646.6 RKO98361.1 - 9e-06 26.0 10.7 0.012 16.0 0.8 4.7 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 RKO98361.1 - 0.00041 20.4 2.0 0.83 9.7 0.1 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RKO98361.1 - 0.013 15.7 11.6 2.5 8.6 0.4 6.1 6 0 0 6 6 6 0 HEAT repeat DUF1039 PF06287.11 RKO98361.1 - 0.067 13.6 1.2 14 6.2 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1039) Cep57_MT_bd PF06657.13 RKO98362.1 - 0.00018 21.9 0.3 0.48 10.9 0.2 2.6 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 VHS PF00790.19 RKO98363.1 - 1.8e-40 138.1 0.0 3.6e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 RKO98363.1 - 7e-10 39.1 1.0 3.5e-09 36.9 0.0 2.7 3 0 0 3 3 3 1 GAT domain Nsp1_C PF05064.13 RKO98363.1 - 0.019 14.8 0.3 0.073 12.9 0.0 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region KxDL PF10241.9 RKO98363.1 - 0.026 14.8 0.7 3.9 7.8 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein ISG65-75 PF11727.8 RKO98363.1 - 0.044 13.0 0.3 0.081 12.1 0.3 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Hist_deacetyl PF00850.19 RKO98364.1 - 1.4e-83 280.9 0.0 1.8e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Acyl_transf_1 PF00698.21 RKO98365.1 - 3e-20 73.0 1.6 9.7e-18 64.7 1.4 2.4 1 1 0 2 2 2 1 Acyl transferase domain ubiquitin PF00240.23 RKO98366.1 - 1.1e-06 28.3 0.1 1.9e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RKO98366.1 - 0.0066 16.9 0.0 0.046 14.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RKO98366.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM PF00493.23 RKO98367.1 - 3.2e-100 333.9 0.0 5.8e-100 333.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RKO98367.1 - 3.2e-31 107.8 4.4 7.5e-31 106.6 4.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKO98367.1 - 4.4e-19 68.7 0.0 1.6e-18 66.9 0.0 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RKO98367.1 - 1.7e-13 51.0 0.1 4.1e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RKO98367.1 - 6.1e-07 29.0 0.1 2.6e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKO98367.1 - 5.4e-05 23.2 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO98367.1 - 0.0039 17.6 0.4 0.85 10.0 0.1 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 RKO98367.1 - 0.031 14.1 0.0 0.13 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RKO98367.1 - 0.09 12.5 0.1 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 RKO98367.1 - 0.18 12.4 2.7 0.24 12.0 0.2 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Cyclin PF08613.11 RKO98369.1 - 0.0077 16.6 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin Hydrophobin PF01185.18 RKO98370.1 - 3.6e-07 30.7 12.8 5.1e-07 30.2 12.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Frataxin_Cyay PF01491.16 RKO98371.1 - 3.7e-26 91.3 0.0 4e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Ribosomal_L9_N PF01281.19 RKO98372.1 - 1.7e-10 40.3 0.0 2.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 RKO98372.1 - 0.049 14.1 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain GDI PF00996.18 RKO98373.1 - 5.5e-31 107.5 0.0 4.8e-22 78.1 0.0 2.3 2 0 0 2 2 2 2 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 RKO98373.1 - 0.073 12.3 1.2 0.078 12.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO98373.1 - 0.2 12.2 1.8 0.32 11.6 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDA1_CD39 PF01150.17 RKO98377.1 - 5.7e-92 308.6 0.0 7.1e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family U3_assoc_6 PF08640.11 RKO98378.1 - 2.1e-27 95.0 1.0 2.4e-26 91.6 0.2 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 RKO98378.1 - 2e-06 28.1 1.0 0.0027 18.4 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat KIX_2 PF16987.5 RKO98378.1 - 0.084 12.9 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 KIX domain Syntaxin PF00804.25 RKO98379.1 - 4.3e-43 147.3 14.6 4.3e-43 147.3 14.6 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 RKO98379.1 - 4.8e-13 48.9 2.0 1e-12 47.8 2.0 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 RKO98379.1 - 1.5e-07 31.7 8.1 1.5e-07 31.7 8.1 2.6 2 1 0 2 2 2 1 Syntaxin-like protein PAH PF02671.21 RKO98379.1 - 0.019 15.1 0.1 0.036 14.2 0.1 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat VitD-bind_III PF09164.10 RKO98379.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.4 3 0 0 3 3 3 0 Vitamin D binding protein, domain III TraG_N PF07916.11 RKO98379.1 - 2.1 7.1 7.9 2.7 6.7 2.9 2.0 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Syntaxin-6_N PF09177.11 RKO98379.1 - 2.2 8.9 8.6 5.4 7.6 3.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 RKO98379.1 - 2.2 8.3 9.8 0.51 10.4 1.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 RKO98379.1 - 2.6 6.6 17.4 0.24 10.0 11.3 1.9 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.12 RKO98379.1 - 2.7 8.3 17.8 1.2 9.4 1.2 4.6 4 1 0 5 5 5 0 Proteins of 100 residues with WXG Peptidase_S46 PF10459.9 RKO98379.1 - 4.8 5.7 15.8 7.4 5.1 15.8 1.3 1 1 0 1 1 1 0 Peptidase S46 DAO PF01266.24 RKO98381.1 - 9.6e-48 163.5 3.1 1.2e-47 163.3 3.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 RKO98381.1 - 2e-11 43.6 0.0 5.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_2 PF00890.24 RKO98381.1 - 3.2e-07 29.8 1.1 6.2e-07 28.8 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 RKO98381.1 - 1.9e-06 28.0 1.1 4.8e-06 26.7 0.5 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RKO98381.1 - 7.9e-06 25.2 0.0 0.00064 18.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 RKO98381.1 - 1.9e-05 24.0 0.8 0.00011 21.6 0.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKO98381.1 - 0.00014 21.2 0.6 0.00025 20.4 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 RKO98381.1 - 0.00088 18.1 1.1 0.00097 17.9 0.3 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 RKO98381.1 - 0.0029 17.6 0.3 0.57 10.2 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 RKO98381.1 - 0.0059 16.0 2.2 0.026 13.9 2.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RKO98381.1 - 0.011 14.9 0.3 0.068 12.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 RKO98381.1 - 0.012 14.7 0.6 0.082 12.0 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 RKO98381.1 - 0.017 15.5 0.1 0.053 14.0 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 RKO98381.1 - 0.021 14.1 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 RKO98381.1 - 0.027 15.0 0.3 0.088 13.4 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RKO98381.1 - 0.041 13.2 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 RKO98381.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 RKO98381.1 - 0.063 13.5 0.4 0.14 12.4 0.4 1.6 1 0 0 1 1 1 0 TrkA-N domain CUE PF02845.16 RKO98382.1 - 3.7e-07 29.7 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 RKO98382.1 - 0.23 11.1 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 DMRTA motif Hydrophobin PF01185.18 RKO98383.1 - 7.2e-08 33.0 12.5 1.1e-07 32.4 12.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2953 PF11167.8 RKO98383.1 - 5.3 7.2 0.0 5.3 7.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2953) CLU PF13236.6 RKO98384.1 - 2.3e-13 50.5 0.0 4.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 RKO98384.1 - 2.3e-12 47.0 21.7 1.5e-08 34.8 3.2 5.5 4 1 1 6 6 6 4 Tetratricopeptide repeat eIF3_p135 PF12807.7 RKO98384.1 - 4.6e-12 46.3 0.3 8.5e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PH PF00169.29 RKO98384.1 - 1.8e-08 34.8 0.0 4.1e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 PH domain TPR_MalT PF17874.1 RKO98384.1 - 1.1e-06 28.3 11.5 1.1e-06 28.3 11.5 1.8 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 RKO98384.1 - 1.7e-06 27.6 4.7 0.11 12.5 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 RKO98384.1 - 0.00023 20.9 15.0 1.4 8.9 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat PH_11 PF15413.6 RKO98384.1 - 0.00023 21.6 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_2 PF07719.17 RKO98384.1 - 0.0037 17.3 16.8 0.47 10.7 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98384.1 - 0.017 14.9 12.5 0.032 14.1 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 RKO98384.1 - 0.069 12.6 0.2 0.17 11.3 0.2 1.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 RKO98384.1 - 0.12 12.6 4.1 5.4 7.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PHD PF00628.29 RKO98385.1 - 4.9e-05 23.1 3.8 0.0002 21.2 3.8 2.0 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 RKO98385.1 - 0.053 13.4 0.7 0.12 12.3 0.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DDT PF02791.17 RKO98385.1 - 0.22 11.9 0.2 0.38 11.1 0.2 1.3 1 0 0 1 1 1 0 DDT domain RGS PF00615.19 RKO98386.1 - 1.1e-07 32.2 0.0 2.4e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain GATA-N PF05349.12 RKO98386.1 - 0.058 13.7 2.0 0.13 12.6 0.5 2.1 2 0 0 2 2 2 0 GATA-type transcription activator, N-terminal UPF0492 PF15744.5 RKO98386.1 - 0.19 10.9 0.0 0.99 8.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0492 AzlD PF05437.12 RKO98386.1 - 2.5 8.3 14.9 0.56 10.4 0.3 3.4 4 0 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) Glyco_transf_34 PF05637.12 RKO98387.1 - 3.2e-08 33.6 0.0 0.03 14.0 0.1 2.9 1 1 2 3 3 3 3 galactosyl transferase GMA12/MNN10 family Glyco_hydro_114 PF03537.13 RKO98388.1 - 6.8e-53 179.4 0.1 9.5e-53 178.9 0.1 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SLAC1 PF03595.17 RKO98389.1 - 1e-76 258.3 41.5 1.3e-76 258.0 41.5 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel EPSP_synthase PF00275.20 RKO98390.1 - 2.1e-113 379.2 0.3 3.4e-113 378.5 0.3 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 RKO98390.1 - 4.8e-97 324.2 0.1 1.1e-96 323.1 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 RKO98390.1 - 7.9e-36 124.4 0.0 6.1e-35 121.5 0.0 2.3 2 1 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 RKO98390.1 - 4.8e-29 101.5 0.0 2.7e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 RKO98390.1 - 1.5e-14 54.0 0.0 3.8e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 RKO98390.1 - 1.3e-08 34.8 0.5 2.3e-08 34.0 0.5 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 RKO98390.1 - 1.1e-07 31.5 0.3 1.1e-07 31.5 0.3 2.6 3 0 0 3 3 3 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 RKO98390.1 - 3.6e-05 23.9 0.0 8.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 RKO98390.1 - 0.043 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain SchA_CurD PF04486.12 RKO98390.1 - 0.089 12.9 0.0 5.5 7.1 0.0 2.9 3 0 0 3 3 3 0 SchA/CurD like domain Promethin PF16015.5 RKO98394.1 - 0.048 13.6 13.1 0.069 13.1 13.1 1.2 1 0 0 1 1 1 0 Promethin Glyco_transf_92 PF01697.27 RKO98395.1 - 2.6e-17 63.3 1.5 7.1e-17 61.9 1.5 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RKO98395.1 - 5e-07 30.2 0.6 5.6e-06 26.8 0.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 ATP-synt_DE PF00401.20 RKO98395.1 - 0.82 10.0 5.3 0.5 10.7 2.1 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Tma16 PF11176.8 RKO98396.1 - 2.9e-20 72.7 0.0 3.4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 NTP_transferase PF00483.23 RKO98397.1 - 2.1e-13 50.5 0.0 1.2e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKO98397.1 - 5.1e-09 36.7 0.3 8.1e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 RKO98397.1 - 2.6e-08 33.3 7.2 7.7e-05 22.3 5.6 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 RKO98397.1 - 0.00025 19.3 0.6 0.00097 17.4 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Img2 PF05046.14 RKO98398.1 - 1.6e-12 47.5 0.0 2.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) B9-C2 PF07162.11 RKO98400.1 - 9.3e-36 123.6 0.0 1.1e-35 123.4 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein RhoGAP PF00620.27 RKO98401.1 - 4.3e-33 114.3 0.0 1.1e-32 113.0 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 RKO98401.1 - 2.8e-28 98.6 0.0 1e-27 96.7 0.0 1.9 2 0 0 2 2 2 1 MyTH4 domain Tox-GHH2 PF15635.6 RKO98402.1 - 0.11 13.1 0.1 0.31 11.6 0.0 1.8 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 HTH_33 PF13592.6 RKO98405.1 - 0.047 13.3 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix SDA1 PF05285.12 RKO98407.1 - 1.1 8.7 10.1 1.5 8.2 10.1 1.1 1 0 0 1 1 1 0 SDA1 RAB3GAP2_N PF14655.6 RKO98407.1 - 2.9 7.0 5.4 4.8 6.3 5.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RXT2_N PF08595.11 RKO98407.1 - 3.8 7.5 6.9 6.2 6.8 6.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Ribosomal_L7Ae PF01248.26 RKO98409.1 - 8e-18 64.0 1.1 8.5e-13 47.9 0.0 2.3 2 1 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 RKO98409.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 SNARE_assoc PF09335.11 RKO98410.1 - 2.4e-14 53.9 8.4 4.7e-14 52.9 8.4 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4567 PF15131.6 RKO98410.1 - 0.089 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) ABC_tran PF00005.27 RKO98411.1 - 7.3e-49 165.8 0.0 1.8e-23 83.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 RKO98411.1 - 1.6e-43 148.6 53.1 6.5e-28 97.6 21.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter AAA_16 PF13191.6 RKO98411.1 - 3.2e-07 30.9 7.9 0.00015 22.2 0.3 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 RKO98411.1 - 5.7e-07 29.2 0.3 0.043 13.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RKO98411.1 - 7.3e-07 29.3 9.9 0.06 13.1 0.1 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 RKO98411.1 - 1.3e-06 28.6 6.5 0.0073 16.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain cobW PF02492.19 RKO98411.1 - 2e-06 27.5 1.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 RKO98411.1 - 7.3e-06 26.0 0.1 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 RKO98411.1 - 7.7e-06 26.2 0.7 0.044 14.1 0.4 3.1 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 RKO98411.1 - 2.4e-05 24.3 0.4 0.065 13.2 0.1 2.8 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 RKO98411.1 - 5.6e-05 22.7 0.0 1.8 7.9 0.0 3.8 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 RKO98411.1 - 0.00016 21.3 11.5 0.0088 15.6 1.9 4.0 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 RKO98411.1 - 0.00054 20.2 1.9 0.16 12.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 RKO98411.1 - 0.00092 19.8 0.1 1.7 9.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 RKO98411.1 - 0.0012 18.3 0.4 0.88 8.9 0.1 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family CbiA PF01656.23 RKO98411.1 - 0.0027 17.7 0.6 1.5 8.9 0.4 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 RKO98411.1 - 0.0038 17.2 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Roc PF08477.13 RKO98411.1 - 0.0039 17.4 0.4 0.8 9.9 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 RKO98411.1 - 0.0042 16.8 8.1 0.89 9.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 RKO98411.1 - 0.0058 16.7 0.4 2.5 8.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RKO98411.1 - 0.0063 16.6 1.5 2.9 7.9 0.1 2.4 2 0 0 2 2 2 2 Dynamin family Zeta_toxin PF06414.12 RKO98411.1 - 0.0078 15.5 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 RKO98411.1 - 0.0091 15.7 0.1 3.5 7.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RKO98411.1 - 0.0098 16.4 0.1 4.7 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 RKO98411.1 - 0.01 15.9 4.7 1.2 9.2 0.9 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_19 PF13245.6 RKO98411.1 - 0.012 15.9 0.1 8.1 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 RKO98411.1 - 0.018 14.9 0.5 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 RKO98411.1 - 0.029 14.1 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 RKO98411.1 - 0.051 13.6 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 RKO98411.1 - 0.052 12.4 0.1 0.4 9.5 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PRK PF00485.18 RKO98411.1 - 0.063 13.0 0.9 8.1 6.1 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 RKO98411.1 - 0.067 12.4 0.1 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 RKO98411.1 - 0.1 13.0 0.1 8.9 6.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Ras PF00071.22 RKO98411.1 - 0.11 12.1 0.4 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 RKO98411.1 - 0.16 11.1 1.1 7.9 5.5 0.1 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 RKO98411.1 - 0.17 11.6 1.6 8.4 6.1 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UvrD-helicase PF00580.21 RKO98411.1 - 0.18 11.3 0.3 21 4.5 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PduV-EutP PF10662.9 RKO98411.1 - 0.19 11.5 0.2 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 RKO98411.1 - 0.22 10.9 0.9 6.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.17 RKO98411.1 - 0.29 10.9 2.8 20 4.8 0.1 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 RKO98411.1 - 0.29 10.7 1.6 1.9 8.1 0.4 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Septin PF00735.18 RKO98411.1 - 0.33 10.2 0.2 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Septin ABC2_membrane_3 PF12698.7 RKO98411.1 - 7.9 5.5 37.3 0.049 12.8 17.0 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein Zds_C PF08632.10 RKO98412.1 - 3.6e-12 45.8 0.0 6.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Synaptobrevin PF00957.21 RKO98413.1 - 5.5e-22 77.4 0.3 5.9e-22 77.3 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin TTL PF03133.15 RKO98413.1 - 0.013 14.6 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Herpes_teg_N PF04843.12 RKO98413.1 - 0.066 12.9 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Ras PF00071.22 RKO98415.1 - 6.7e-54 181.8 0.0 7.8e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO98415.1 - 1.3e-21 77.0 0.0 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO98415.1 - 9.9e-08 31.6 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO98415.1 - 0.0027 17.3 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LIM PF00412.22 RKO98416.1 - 5.6e-08 32.9 6.1 8.4e-08 32.3 6.1 1.2 1 0 0 1 1 1 1 LIM domain PK PF00224.21 RKO98417.1 - 7.1e-102 340.8 0.5 9e-102 340.5 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RKO98417.1 - 8.3e-25 87.3 0.5 2e-24 86.1 0.1 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain TPR_14 PF13428.6 RKO98418.1 - 0.42 11.6 0.0 0.42 11.6 0.0 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 RKO98419.1 - 0.1 11.6 0.1 0.35 9.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region PDZ_3 PF17815.1 RKO98419.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain HSCB_C PF07743.13 RKO98422.1 - 2.1e-10 41.0 0.1 4.1e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 RKO98422.1 - 0.075 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 DnaJ domain DZR PF12773.7 RKO98422.1 - 0.15 12.1 2.0 0.26 11.4 0.9 1.9 2 0 0 2 2 2 0 Double zinc ribbon ParBc PF02195.18 RKO98424.1 - 0.00027 21.2 0.0 0.0016 18.7 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain DUF1015 PF06245.11 RKO98424.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1015) Tr-sialidase_C PF11052.8 RKO98424.1 - 0.35 11.0 7.5 0.8 9.9 7.5 1.6 1 0 0 1 1 1 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal 3HCDH_N PF02737.18 RKO98425.1 - 1.5e-45 155.2 0.2 1.9e-45 155.0 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RKO98425.1 - 1.1e-33 115.7 0.0 2.1e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Peroxin-3 PF04882.12 RKO98426.1 - 8.8e-76 255.8 0.0 2.1e-55 188.6 0.0 2.1 1 1 1 2 2 2 2 Peroxin-3 CAP_N PF01213.19 RKO98426.1 - 2 7.8 5.8 3.6 7.0 5.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Helicase_C PF00271.31 RKO98428.1 - 3.9e-14 52.9 0.0 9.1e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 RKO98428.1 - 1.4e-08 35.0 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 RKO98428.1 - 2.2e-06 27.5 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO98428.1 - 0.00083 19.4 0.0 0.0065 16.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 RKO98428.1 - 0.0063 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 RKO98428.1 - 0.0065 16.7 0.2 0.041 14.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 RKO98428.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 RKO98428.1 - 0.0096 16.3 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO98428.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RKO98428.1 - 0.15 11.5 0.0 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ERCC4 PF02732.15 RKO98429.1 - 4.5e-13 49.7 0.0 8.8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Ribosomal_L37e PF01907.19 RKO98430.1 - 3.9e-28 97.4 10.6 7.1e-28 96.5 10.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 RKO98430.1 - 0.004 17.1 1.2 0.0071 16.3 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 RKO98430.1 - 0.018 15.0 0.7 0.026 14.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_6 PF14599.6 RKO98430.1 - 0.07 13.2 2.7 0.12 12.4 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon DUF35_N PF12172.8 RKO98430.1 - 0.1 12.5 6.5 0.25 11.2 6.5 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C3HC4_2 PF13923.6 RKO98430.1 - 0.75 9.7 5.1 1.3 9.0 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 RKO98431.1 - 1.1e-08 35.0 5.0 1.1e-05 25.6 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO98431.1 - 7.5e-08 32.5 3.0 2e-05 24.8 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO98431.1 - 1.1e-06 29.0 4.7 0.0024 18.5 2.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO98431.1 - 0.0022 18.2 0.1 2.3 8.6 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RKO98431.1 - 0.0057 16.4 2.1 1.5 8.7 1.0 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RKO98431.1 - 0.018 14.8 0.2 0.075 12.8 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 RKO98431.1 - 0.028 14.1 0.8 1.3 8.8 0.5 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 RKO98431.1 - 0.42 11.1 4.1 1 9.8 0.7 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FhuF_C PF11575.8 RKO98431.1 - 0.44 10.5 5.6 6 6.9 0.3 2.2 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Pkinase PF00069.25 RKO98432.1 - 1e-06 28.3 0.0 3.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98432.1 - 0.00014 21.2 0.0 0.00047 19.5 0.0 1.5 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO98432.1 - 0.00092 18.1 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKO98432.1 - 0.043 13.2 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NO_synthase PF02898.15 RKO98434.1 - 3.3e-120 401.4 0.0 3.7e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain NAD_binding_1 PF00175.21 RKO98435.1 - 2.2e-15 57.2 0.0 2.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DEAD PF00270.29 RKO98437.1 - 8e-44 149.5 0.0 2e-43 148.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98437.1 - 2.1e-29 102.1 0.2 1.2e-28 99.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain WRNPLPNID PF15017.6 RKO98438.1 - 0.19 12.6 0.3 0.43 11.5 0.3 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF5421 PF17458.2 RKO98439.1 - 0.12 11.7 1.4 0.15 11.4 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) PHD PF00628.29 RKO98440.1 - 6.5e-08 32.3 9.5 1.1e-07 31.7 9.5 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKO98440.1 - 0.27 10.8 6.2 0.47 10.1 6.2 1.4 1 0 0 1 1 1 0 PHD-finger CENP-B_dimeris PF09026.10 RKO98440.1 - 0.74 10.2 8.8 1.7 9.1 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PP2C PF00481.21 RKO98441.1 - 2e-07 30.9 0.0 0.00062 19.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Aim19 PF10315.9 RKO98442.1 - 1.5e-07 31.7 3.8 1.5e-07 31.7 3.8 1.8 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 19 Pkinase PF00069.25 RKO98444.1 - 1.5e-64 218.0 0.0 1.7e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98444.1 - 9.7e-19 67.7 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKO98444.1 - 2.1e-07 31.1 0.2 7.2e-06 26.1 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKO98444.1 - 0.0059 15.4 0.0 0.012 14.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 RKO98444.1 - 0.034 13.7 0.1 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 RKO98444.1 - 0.035 13.4 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.12 RKO98445.1 - 0.052 13.3 9.1 0.093 12.4 9.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 RKO98445.1 - 0.48 10.7 5.8 1.3 9.3 5.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 RKO98445.1 - 2.7 7.2 9.7 4.4 6.5 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_A31 PF05771.11 RKO98447.1 - 0.18 11.8 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A31 protein DUF2408 PF10303.9 RKO98448.1 - 7e-36 123.8 1.2 5.7e-19 69.0 0.0 4.1 3 1 1 4 4 4 3 Protein of unknown function (DUF2408) Alpha-2-MRAP_C PF06401.11 RKO98448.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Allexi_40kDa PF05549.11 RKO98448.1 - 0.2 11.1 1.4 2.9 7.3 0.1 2.7 3 0 0 3 3 3 0 Allexivirus 40kDa protein PTPLA PF04387.14 RKO98449.1 - 7.7e-48 162.3 13.3 1.2e-47 161.7 13.3 1.3 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PseudoU_synth_1 PF01416.20 RKO98451.1 - 1.4e-32 112.4 0.0 6.5e-28 97.3 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 RKO98452.1 - 2e-09 37.9 0.7 0.0023 18.7 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98452.1 - 0.18 12.1 0.0 5.5 7.4 0.0 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain V_ATPase_I PF01496.19 RKO98455.1 - 8.4 4.2 16.3 13 3.6 16.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ala_racemase_N PF01168.20 RKO98456.1 - 2.3e-22 79.7 1.0 2.8e-22 79.5 1.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF2870 PF11069.8 RKO98457.1 - 4.7e-33 113.4 0.0 7.1e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Sod_Fe_C PF02777.18 RKO98458.1 - 1e-35 122.0 0.3 2.2e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 RKO98458.1 - 4.9e-29 100.6 0.6 8.4e-29 99.9 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PEPCK_ATP PF01293.20 RKO98460.1 - 6.5e-217 720.7 0.0 8e-217 720.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 RKO98460.1 - 0.03 14.7 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 RKO98460.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RKO98460.1 - 0.18 11.6 0.2 0.72 9.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain BolA PF01722.18 RKO98462.1 - 3.3e-16 59.3 0.0 8.3e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein DUF4551 PF15087.6 RKO98463.1 - 2.2 7.0 9.1 2.4 6.9 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CytochromB561_N PF09786.9 RKO98463.1 - 2.8 6.8 7.6 3 6.7 7.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SRP-alpha_N PF04086.13 RKO98463.1 - 5.1 6.9 13.2 6.6 6.6 13.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PRR20 PF15708.5 RKO98464.1 - 0.0073 16.2 2.3 0.0085 16.0 2.3 1.1 1 0 0 1 1 1 1 Proline-rich protein family 20 TRAM_LAG1_CLN8 PF03798.16 RKO98465.1 - 4.4e-33 114.7 11.6 1e-32 113.5 9.8 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 RKO98465.1 - 0.028 14.1 1.1 0.055 13.1 0.1 2.1 2 0 0 2 2 2 0 TRAM1-like protein RgpF PF05045.12 RKO98465.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F DUF3742 PF12553.8 RKO98465.1 - 0.39 10.8 8.8 5.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DUF4834 PF16118.5 RKO98465.1 - 0.73 10.8 2.1 3.3 8.7 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) SURF4 PF02077.15 RKO98466.1 - 3.5e-93 312.1 7.3 4e-93 311.9 7.3 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 RKO98466.1 - 0.00038 20.5 8.9 0.00068 19.7 8.9 1.5 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter DUF2236 PF09995.9 RKO98467.1 - 2.9e-22 80.0 10.4 3.9e-22 79.6 9.4 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Yos1 PF08571.10 RKO98468.1 - 4.1e-30 103.9 0.1 6.1e-30 103.3 0.1 1.3 1 0 0 1 1 1 1 Yos1-like SfLAP PF11139.8 RKO98468.1 - 0.0018 17.7 2.8 0.0025 17.3 2.8 1.2 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein ORC2 PF04084.14 RKO98469.1 - 1.2e-78 264.4 0.0 1.3e-78 264.2 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SURF6 PF04935.12 RKO98470.1 - 3.6e-23 82.4 36.0 3.6e-23 82.4 36.0 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 RKO98470.1 - 2.9e-12 47.0 0.5 2.9e-12 47.0 0.5 5.0 3 1 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 zf-Nse PF11789.8 RKO98471.1 - 4e-14 52.2 0.0 6.6e-14 51.5 0.0 1.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 RKO98471.1 - 0.00044 20.0 0.4 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 RKO98471.1 - 0.0025 17.8 0.1 0.0091 16.0 0.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.12 RKO98471.1 - 0.0028 17.1 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 RKO98471.1 - 0.0056 16.5 0.3 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKO98471.1 - 0.0061 16.7 0.4 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 RKO98471.1 - 0.03 14.5 0.0 0.3 11.3 0.0 1.9 1 1 1 2 2 2 0 U-box domain tRNA-synt_1c PF00749.21 RKO98472.1 - 1.5e-110 369.0 0.2 2.1e-110 368.5 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RKO98472.1 - 5e-33 114.4 0.2 1.3e-32 113.1 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 RKO98472.1 - 0.00023 21.3 0.0 0.00061 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 RKO98472.1 - 0.081 12.3 0.7 0.58 9.5 0.7 2.0 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA_bind PF01588.20 RKO98473.1 - 7.6e-29 99.7 0.0 1.1e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Ribosomal_60s PF00428.19 RKO98473.1 - 7.3 7.3 13.7 13 6.4 13.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pro_isomerase PF00160.21 RKO98476.1 - 8e-47 159.4 0.3 1.4e-46 158.7 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 RKO98476.1 - 1.1e-11 43.9 1.3 1.5e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98476.1 - 1.4e-11 43.7 5.9 4e-07 29.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKO98476.1 - 1.4e-10 40.6 4.8 0.00018 21.1 0.4 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 RKO98476.1 - 1e-07 31.6 2.4 0.0004 20.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO98476.1 - 0.00015 21.9 0.9 0.63 10.4 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKO98476.1 - 0.00052 20.6 1.3 0.34 11.8 0.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKO98476.1 - 0.00056 20.0 0.6 0.021 15.0 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKO98476.1 - 0.013 15.5 0.1 2.3 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RKO98476.1 - 0.022 15.4 10.7 0.13 12.9 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat PA28_beta PF02252.18 RKO98476.1 - 0.14 11.9 0.2 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit TPR_19 PF14559.6 RKO98476.1 - 0.18 12.4 6.3 4.5 7.9 2.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO98476.1 - 1.8 9.4 14.0 2 9.2 0.4 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Arm PF00514.23 RKO98477.1 - 7.6e-13 48.0 19.6 0.00055 19.9 0.0 8.3 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKO98477.1 - 1.4e-09 38.2 7.5 0.0026 18.1 0.2 4.4 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 RKO98477.1 - 3.5e-07 30.4 0.1 0.012 15.7 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RKO98477.1 - 5.2e-05 23.6 1.7 0.0096 16.4 0.1 4.9 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 RKO98477.1 - 0.00016 20.4 0.1 0.017 13.7 0.0 2.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 RKO98477.1 - 0.0012 18.4 0.2 0.089 12.2 0.1 2.6 2 0 0 2 2 2 1 Armadillo-like ScsC_N PF18312.1 RKO98477.1 - 0.0078 16.0 0.7 0.021 14.7 0.7 1.7 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain HEAT PF02985.22 RKO98477.1 - 0.031 14.5 17.8 1.1 9.7 0.0 8.1 9 0 0 9 9 9 0 HEAT repeat DUF4491 PF14898.6 RKO98477.1 - 0.072 13.5 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) gag_pre-integrs PF13976.6 RKO98479.1 - 6.7e-07 29.1 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain F-box-like PF12937.7 RKO98480.1 - 1.8e-07 31.0 4.5 5.3e-07 29.4 1.4 3.2 3 0 0 3 3 3 1 F-box-like Spt20 PF12090.8 RKO98480.1 - 0.064 12.9 7.8 0.34 10.5 7.0 2.1 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 RKO98480.1 - 3.1 7.7 11.8 0.46 10.4 7.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PhoLip_ATPase_C PF16212.5 RKO98481.1 - 7.2e-69 232.3 22.9 7.2e-69 232.3 22.9 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKO98481.1 - 1.1e-20 73.1 1.6 1.1e-20 73.1 1.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RKO98481.1 - 1.6e-14 53.8 0.0 4.6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RKO98481.1 - 3.6e-11 43.7 1.5 2.2e-06 28.1 0.7 3.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RKO98481.1 - 1e-05 25.2 0.1 9.9e-05 21.9 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RKO98481.1 - 0.00042 20.1 0.5 0.0088 15.8 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 RKO98482.1 - 3.6e-12 46.6 0.2 0.00091 20.0 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98482.1 - 1.2e-07 31.9 0.0 0.0014 18.9 0.0 4.8 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO98482.1 - 0.0038 16.2 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Polysacc_synt_C PF14667.6 RKO98482.1 - 0.32 11.0 3.1 0.75 9.9 3.1 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain TPR_1 PF00515.28 RKO98484.1 - 0.00047 19.8 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKO98484.1 - 0.0092 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF5129 PF17173.4 RKO98484.1 - 0.1 11.7 3.5 0.39 9.8 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5129) zf-RING_2 PF13639.6 RKO98485.1 - 7e-09 35.9 13.6 2.9e-08 33.9 5.0 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 RKO98485.1 - 4.6e-05 23.6 3.5 4.6e-05 23.6 3.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RKO98485.1 - 0.00081 19.2 4.6 0.00081 19.2 4.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 RKO98485.1 - 0.0017 18.5 15.5 0.0017 18.5 15.5 3.6 3 1 1 4 4 3 1 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 RKO98485.1 - 0.0023 17.6 1.3 0.0023 17.6 1.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger PHD PF00628.29 RKO98485.1 - 0.0058 16.5 1.5 0.0058 16.5 1.5 2.3 2 0 0 2 2 2 1 PHD-finger Baculo_RING PF05883.11 RKO98485.1 - 0.13 12.2 0.3 0.24 11.4 0.3 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD_2 PF13831.6 RKO98485.1 - 0.14 11.7 0.1 0.53 9.9 0.1 1.9 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 RKO98485.1 - 0.19 11.9 3.1 0.46 10.7 3.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.6 RKO98485.1 - 0.5 10.4 5.5 1.1 9.3 5.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RKO98485.1 - 0.87 9.3 13.3 0.17 11.5 3.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF2992 PF11208.8 RKO98485.1 - 6.3 7.0 5.9 14 5.9 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) RVT_1 PF00078.27 RKO98486.1 - 2e-06 27.5 0.0 2.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_clus PF00172.18 RKO98488.1 - 0.038 14.1 16.6 0.057 13.5 16.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PEX11 PF05648.14 RKO98489.1 - 3.4e-18 65.9 0.1 1.4e-08 34.5 0.1 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF4051 PF13260.6 RKO98489.1 - 0.19 11.5 0.2 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Alpha-amylase PF00128.24 RKO98490.1 - 9.6e-21 74.7 0.3 1e-16 61.5 0.0 3.9 4 0 0 4 4 4 2 Alpha amylase, catalytic domain DUF4305 PF14146.6 RKO98490.1 - 0.073 13.3 0.4 0.78 10.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) Ank_2 PF12796.7 RKO98491.1 - 4.7e-25 88.0 0.1 3.8e-10 40.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKO98491.1 - 2.9e-21 75.3 0.2 6.4e-11 42.3 0.0 3.9 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RKO98491.1 - 5.7e-21 74.6 0.2 4.3e-07 30.3 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKO98491.1 - 4.4e-20 69.6 0.0 0.003 17.9 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RKO98491.1 - 1.6e-12 47.3 0.3 0.047 14.2 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ribosomal_L21p PF00829.21 RKO98492.1 - 4.7e-15 55.7 0.1 5.5e-15 55.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.25 RKO98493.1 - 1.3e-71 240.6 0.0 2e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 RKO98493.1 - 5.6e-46 156.0 0.1 9.8e-46 155.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 RKO98493.1 - 1.5e-19 70.3 2.7 5.4e-19 68.5 2.7 2.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 RKO98493.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea HAS-barrel PF09378.10 RKO98493.1 - 0.093 12.9 2.7 1.6 9.0 0.1 2.7 1 1 1 2 2 2 0 HAS barrel domain ASH PF15780.5 RKO98494.1 - 1.1e-22 80.1 6.9 0.00013 22.1 0.0 12.4 13 0 0 13 13 13 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RKO98494.1 - 1.1e-12 47.9 3.4 0.041 14.1 0.0 7.0 7 0 0 7 7 7 3 Flagellar-associated PapD-like DUF1573 PF07610.11 RKO98494.1 - 9.7e-10 38.4 0.0 2.5 8.2 0.0 8.3 9 0 0 9 9 9 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 RKO98494.1 - 9.6e-06 25.4 0.0 0.26 11.1 0.0 6.4 8 1 0 8 8 8 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RKO98494.1 - 0.00013 22.2 1.1 4.6 7.6 0.0 5.7 6 1 0 6 6 6 1 Transmembrane protein 131-like MYCBPAP PF14646.6 RKO98494.1 - 0.0011 18.0 0.0 0.28 10.1 0.0 4.0 4 0 0 4 4 4 1 MYCBP-associated protein family IQ PF00612.27 RKO98496.1 - 2.1e-07 30.1 16.9 8.1e-05 22.1 0.6 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif Alg6_Alg8 PF03155.15 RKO98497.1 - 5.8e-99 332.2 23.7 7.9e-99 331.8 23.7 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family AhpC-TSA PF00578.21 RKO98499.1 - 1.1e-26 93.1 0.0 1.4e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO98499.1 - 6.4e-19 68.1 0.0 7.5e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 RKO98499.1 - 0.0041 17.2 0.0 0.01 15.9 0.0 1.8 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme CRISPR_Cse2 PF09485.10 RKO98500.1 - 0.78 10.3 6.0 3.3 8.2 6.0 2.2 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) HSP20 PF00011.21 RKO98501.1 - 1.2e-07 31.8 0.1 3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.16 RKO98501.1 - 0.012 16.6 0.0 0.024 15.6 0.0 1.6 1 1 0 1 1 1 0 CS domain Vma12 PF11712.8 RKO98501.1 - 0.05 13.7 0.2 0.081 13.0 0.2 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mito_carr PF00153.27 RKO98502.1 - 1.3e-65 217.3 2.2 8.8e-23 80.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nodulin PF02451.15 RKO98502.1 - 0.15 11.6 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Nodulin LAMTOR PF15454.6 RKO98503.1 - 6.1e-05 23.6 0.0 0.0018 18.8 0.0 2.6 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator baeRF_family10 PF18854.1 RKO98503.1 - 0.056 13.7 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 S-AdoMet_synt_C PF02773.16 RKO98504.1 - 1.7e-66 222.4 0.2 1.7e-66 222.4 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 RKO98504.1 - 1.4e-44 150.8 1.6 3.4e-44 149.5 0.3 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 RKO98504.1 - 2.7e-44 150.2 0.0 6.2e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 RKO98504.1 - 0.051 12.4 0.2 0.12 11.1 0.1 1.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DnaJ PF00226.31 RKO98505.1 - 2.2e-09 37.3 0.1 4.1e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain LcrG PF07216.12 RKO98505.1 - 0.068 13.1 5.0 3.5 7.6 0.1 2.4 2 0 0 2 2 2 0 LcrG protein HSP20 PF00011.21 RKO98507.1 - 1.3e-09 38.1 0.3 5e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family DUF3841 PF12952.7 RKO98507.1 - 0.027 14.3 0.2 0.036 13.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) zf-RING_2 PF13639.6 RKO98508.1 - 2e-08 34.4 2.1 2e-08 34.4 2.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RKO98508.1 - 1.5e-06 27.9 1.5 2.9e-06 27.0 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO98508.1 - 2.6e-06 27.3 0.5 7.4e-06 25.9 0.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RKO98508.1 - 7e-06 26.2 3.3 4.4e-05 23.7 3.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO98508.1 - 0.001 18.9 1.8 0.0021 18.0 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RKO98508.1 - 0.0013 18.5 2.3 0.0042 16.9 2.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKO98508.1 - 0.005 17.0 1.7 0.0058 16.8 0.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RKO98508.1 - 0.0052 16.8 0.6 0.014 15.4 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RKO98508.1 - 0.0068 16.2 4.4 0.013 15.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKO98508.1 - 0.0073 16.0 1.1 0.0073 16.0 1.1 2.5 3 0 0 3 3 3 1 RING-like zinc finger FANCL_C PF11793.8 RKO98508.1 - 0.055 13.6 2.5 0.16 12.2 2.2 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RKO98508.1 - 6.1 6.5 8.2 0.61 9.8 3.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type HMG_box PF00505.19 RKO98509.1 - 4e-09 36.8 0.2 6.2e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO98509.1 - 0.008 16.7 0.1 0.013 16.0 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain RXT2_N PF08595.11 RKO98509.1 - 0.021 14.8 0.6 0.041 13.9 0.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.13 RKO98509.1 - 0.47 10.4 5.9 0.94 9.4 5.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 RKO98509.1 - 0.56 10.4 11.8 1.1 9.5 11.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 RKO98509.1 - 1.1 8.6 4.7 2 7.7 4.7 1.3 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RKO98509.1 - 1.1 7.3 18.3 1.7 6.6 18.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RKO98509.1 - 6.2 4.9 9.5 10 4.1 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RKO98509.1 - 8.6 5.7 9.2 17 4.7 9.2 1.3 1 0 0 1 1 1 0 SDA1 Ribosomal_L27A PF00828.19 RKO98510.1 - 2.8e-14 53.9 0.0 3.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TMA7 PF09072.10 RKO98511.1 - 4.2e-24 85.2 16.1 4.6e-24 85.0 16.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Polysacc_deac_1 PF01522.21 RKO98512.1 - 7.4e-15 54.9 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 RKO98512.1 - 0.003 16.8 0.0 0.0061 15.8 0.0 1.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 FEZ PF07763.13 RKO98512.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein SRP40_C PF05022.12 RKO98513.1 - 5e-29 101.0 3.0 5.5e-29 100.8 3.0 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF4974 PF16344.5 RKO98513.1 - 0.027 14.5 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) DUF5578 PF17741.1 RKO98514.1 - 1.7e-46 158.9 0.2 1.9e-32 112.8 0.0 3.2 3 0 0 3 3 3 3 Family of unknown function (DUF5578) DUF3246 PF11596.8 RKO98515.1 - 0.15 11.5 0.2 0.35 10.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SMC_N PF02463.19 RKO98516.1 - 5.9e-71 238.4 0.2 7.4e-71 238.1 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RKO98516.1 - 8.5e-27 93.8 0.0 8.5e-27 93.8 0.0 3.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RKO98516.1 - 9.2e-14 51.9 0.1 4e-07 30.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RKO98516.1 - 1.8e-09 37.8 0.0 7.2e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 RKO98516.1 - 1.4e-08 35.5 9.9 1.4e-08 35.5 9.9 5.2 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 RKO98516.1 - 5.7e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RKO98516.1 - 0.011 16.3 18.3 0.18 12.3 0.0 5.7 5 2 0 5 5 5 0 ABC transporter AAA_18 PF13238.6 RKO98516.1 - 0.23 12.0 1.9 3 8.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 RKO98516.1 - 0.46 9.9 6.6 0.04 13.4 0.8 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF1664 PF07889.12 RKO98516.1 - 2.1 8.4 32.1 1.5 8.8 2.8 6.2 4 1 0 5 5 5 0 Protein of unknown function (DUF1664) SDA1 PF05285.12 RKO98517.1 - 3.7 6.9 23.2 0.78 9.1 15.8 2.3 2 0 0 2 2 2 0 SDA1 Ribonuc_red_sm PF00268.21 RKO98518.1 - 1e-116 389.3 0.0 1.2e-116 389.1 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MRP-L20 PF12824.7 RKO98519.1 - 1.3e-08 35.2 0.0 1.3e-08 35.2 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 RKO98519.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Neugrin DUF1664 PF07889.12 RKO98520.1 - 0.053 13.6 1.5 0.13 12.3 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5427 PF10310.9 RKO98520.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5427) HHH_2 PF12826.7 RKO98520.1 - 0.16 12.1 0.2 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif ECM11 PF15463.6 RKO98520.1 - 0.28 11.8 2.0 2.2 8.9 0.2 2.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 ASFV_J13L PF05568.11 RKO98522.1 - 5.4 6.7 9.2 6.7 6.4 9.2 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Phosphodiest PF01663.22 RKO98524.1 - 6.6e-68 229.9 0.2 1.1e-67 229.2 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RKO98524.1 - 0.002 17.6 0.1 1.5 8.2 0.0 2.1 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.12 RKO98524.1 - 0.012 15.7 0.2 0.022 14.9 0.2 1.3 1 0 0 1 1 1 0 PglZ domain Metalloenzyme PF01676.18 RKO98524.1 - 0.041 13.2 1.1 0.066 12.6 1.1 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily E3_binding PF02817.17 RKO98525.1 - 0.00054 20.2 0.0 0.00054 20.2 0.0 2.8 3 0 0 3 3 3 1 e3 binding domain Y_phosphatase3 PF13350.6 RKO98527.1 - 5.5e-41 141.1 0.0 6.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 RKO98527.1 - 8.2e-08 32.0 0.0 1.7e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKO98527.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 RKO98527.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 RKO98527.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DER1 PF04511.15 RKO98528.1 - 1.7e-28 99.9 0.7 2.1e-28 99.5 0.7 1.0 1 0 0 1 1 1 1 Der1-like family BAH PF01426.18 RKO98529.1 - 1.5e-15 57.1 0.0 2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 RKO98529.1 - 3.5e-14 52.6 0.0 6.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 RKO98531.1 - 1.7e-18 66.6 9.0 2e-06 28.4 1.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98531.1 - 4.9e-09 36.4 0.5 0.039 14.2 0.2 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO98531.1 - 4.3e-07 29.0 0.6 0.0035 16.0 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RKO98531.1 - 0.00086 18.7 0.8 0.0067 15.8 0.2 2.1 3 0 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 RKO98531.1 - 0.008 14.7 0.0 0.75 8.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RKO98531.1 - 0.0092 15.0 1.0 1.6 7.6 0.0 3.6 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 RKO98531.1 - 0.023 14.7 0.1 21 5.2 0.0 3.3 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Lipase_GDSL PF00657.22 RKO98533.1 - 6.9e-09 36.0 0.0 9.7e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RKO98533.1 - 6.5e-08 33.2 0.1 1.8e-07 31.7 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HHH_2 PF12826.7 RKO98533.1 - 0.16 12.1 0.1 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif UQ_con PF00179.26 RKO98534.1 - 1.3e-29 102.6 0.0 1.4e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme KH_1 PF00013.29 RKO98535.1 - 3.3e-17 62.1 1.4 4.4e-09 36.0 0.1 2.6 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 RKO98535.1 - 0.001 18.9 0.3 0.39 10.6 0.0 2.3 2 0 0 2 2 2 2 KH domain FtsJ PF01728.19 RKO98536.1 - 1.4e-66 224.0 0.0 1.7e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ligase_CoA PF00549.19 RKO98539.1 - 8.1e-24 84.2 0.7 1.6e-23 83.2 0.7 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_2 PF08442.10 RKO98539.1 - 4.3e-16 59.1 0.2 2.9e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain DEAD PF00270.29 RKO98540.1 - 8.2e-27 94.1 0.0 4.2e-14 52.7 0.0 2.9 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98540.1 - 2.8e-15 56.6 0.0 6.4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98540.1 - 9.6e-05 22.4 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Kinesin PF00225.23 RKO98541.1 - 1.3e-93 313.6 0.0 1.5e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO98541.1 - 9.7e-19 67.8 0.0 1.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Lum_binding PF00677.17 RKO98543.1 - 3.9e-37 126.1 0.0 1.3e-18 66.8 0.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain Ribosomal_L31e PF01198.19 RKO98545.1 - 3.2e-31 107.4 1.3 4e-31 107.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e HLH PF00010.26 RKO98546.1 - 4.7e-15 55.3 4.3 7.3e-15 54.7 4.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TEBP_beta PF07404.11 RKO98546.1 - 0.24 10.7 6.4 0.38 10.1 6.4 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Glyco_hydro_15 PF00723.21 RKO98548.1 - 2.6e-125 418.7 0.0 3.2e-125 418.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CagZ PF09053.10 RKO98548.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 CagZ DEAD PF00270.29 RKO98549.1 - 1.1e-50 171.8 0.0 1.9e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98549.1 - 1.7e-30 105.7 0.0 2e-29 102.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98549.1 - 5.8e-05 23.2 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKO98549.1 - 0.0012 19.2 0.0 0.02 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 RKO98549.1 - 0.0069 15.7 0.1 0.034 13.5 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 RKO98549.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 RKO98549.1 - 0.024 14.4 0.0 0.14 11.9 0.0 2.2 2 2 0 2 2 2 0 AAA domain PAC2 PF09754.9 RKO98549.1 - 0.036 14.1 0.0 0.083 12.9 0.0 1.5 1 1 0 1 1 1 0 PAC2 family LSM PF01423.22 RKO98550.1 - 3.8e-18 64.9 0.0 4.6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DEAD PF00270.29 RKO98551.1 - 5.4e-41 140.3 0.1 9.2e-41 139.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98551.1 - 1.8e-20 73.4 0.0 7.3e-20 71.4 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RKO98551.1 - 3.1e-15 56.1 0.1 8.1e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RKO98551.1 - 2.5e-10 40.6 0.0 6.4e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M20 PF01546.28 RKO98552.1 - 2.8e-16 59.9 0.0 3.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HMA PF00403.26 RKO98553.1 - 1.4e-10 41.4 0.6 1.6e-10 41.3 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain zf-C4 PF00105.18 RKO98553.1 - 0.055 13.9 0.5 0.069 13.6 0.5 1.4 1 1 0 1 1 1 0 Zinc finger, C4 type (two domains) HydF_tetramer PF18133.1 RKO98553.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.5 1 1 0 1 1 1 0 Hydrogen maturase F tetramerization domain Complex1_LYR_1 PF13232.6 RKO98554.1 - 0.00062 20.3 0.1 0.00099 19.7 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RKO98554.1 - 0.019 15.0 0.2 0.054 13.6 0.2 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) NIPSNAP PF07978.13 RKO98555.1 - 2.4e-40 136.9 3.2 9.9e-28 96.4 0.4 2.1 2 0 0 2 2 2 2 NIPSNAP SF3b10 PF07189.11 RKO98557.1 - 1.7e-29 101.7 0.0 1.9e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Atg14 PF10186.9 RKO98558.1 - 5.1e-13 48.8 0.1 6.3e-11 41.9 0.0 2.7 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 CBFD_NFYB_HMF PF00808.23 RKO98559.1 - 0.0048 17.1 1.8 0.0048 17.1 1.8 2.0 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_membrane PF00664.23 RKO98560.1 - 1.1e-89 300.8 16.2 2.9e-47 161.6 3.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKO98560.1 - 1.1e-69 233.3 0.0 1.6e-33 116.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKO98560.1 - 4.2e-11 42.7 2.2 0.0026 17.2 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RKO98560.1 - 9.8e-09 34.5 0.5 0.0027 16.6 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 RKO98560.1 - 1.3e-06 28.0 0.5 0.0042 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RKO98560.1 - 1.6e-06 28.4 1.8 0.032 14.5 0.1 4.1 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RKO98560.1 - 1.6e-05 24.3 0.0 0.03 13.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 RKO98560.1 - 2.5e-05 24.2 0.2 0.15 12.0 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 RKO98560.1 - 0.00021 21.1 0.0 0.056 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 RKO98560.1 - 0.00025 20.3 0.0 0.42 9.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 RKO98560.1 - 0.00036 21.0 9.3 0.18 12.1 0.3 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 RKO98560.1 - 0.00047 19.9 0.2 1.9 8.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain DUF815 PF05673.13 RKO98560.1 - 0.00081 18.6 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF87 PF01935.17 RKO98560.1 - 0.0025 17.9 0.2 0.15 12.1 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 RKO98560.1 - 0.0042 17.1 0.1 3.6 7.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 RKO98560.1 - 0.0045 16.9 0.1 0.096 12.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 RKO98560.1 - 0.0061 16.2 0.7 3.2 7.3 0.0 3.2 4 0 0 4 4 3 1 AAA domain PRK PF00485.18 RKO98560.1 - 0.014 15.2 0.1 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 RKO98560.1 - 0.024 14.2 2.1 25 4.4 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 RKO98560.1 - 0.027 14.6 0.0 6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 RKO98560.1 - 0.034 14.0 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 RKO98560.1 - 0.051 13.3 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RKO98560.1 - 0.06 12.7 0.0 3.9 6.8 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 RKO98560.1 - 0.074 13.3 2.8 19 5.5 0.2 3.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RKO98560.1 - 0.079 12.5 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Synapsin_N PF10581.9 RKO98560.1 - 0.11 12.5 0.0 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Synapsin N-terminal RNA_helicase PF00910.22 RKO98560.1 - 0.14 12.6 0.2 17 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.6 RKO98560.1 - 0.17 12.2 7.1 7.2 6.9 0.2 4.0 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 RKO98560.1 - 0.22 11.3 0.4 19 4.9 0.0 3.5 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RKO98560.1 - 0.38 11.2 2.4 5.2 7.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 RKO98560.1 - 0.39 9.9 1.4 20 4.2 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain MMR_HSR1 PF01926.23 RKO98560.1 - 0.4 10.8 1.4 30 4.7 0.1 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Tex_YqgF PF16921.5 RKO98560.1 - 7.9 7.0 6.2 59 4.1 0.2 3.3 3 0 0 3 3 3 0 Tex protein YqgF-like domain Chorion_2 PF03964.15 RKO98561.1 - 2.3 9.1 6.3 3.5 8.5 6.3 1.2 1 0 0 1 1 1 0 Chorion family 2 NIF PF03031.18 RKO98563.1 - 4e-24 85.2 0.6 5.4e-24 84.7 0.6 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 RKO98563.1 - 1.4e-06 27.9 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UbiD PF01977.16 RKO98563.1 - 0.0017 17.3 0.3 0.0047 15.8 0.0 1.7 2 0 0 2 2 2 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Kinesin PF00225.23 RKO98564.1 - 3.5e-107 358.2 0.0 4.1e-107 358.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO98564.1 - 9.3e-58 194.4 0.0 1.3e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 RKO98564.1 - 0.0024 17.6 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain PIF1 PF05970.14 RKO98564.1 - 0.01 15.0 0.0 0.071 12.3 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase CENP-Q PF13094.6 RKO98564.1 - 0.015 15.5 0.5 0.027 14.7 0.1 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YabA PF06156.13 RKO98564.1 - 0.026 15.2 0.1 21 5.8 0.0 3.4 3 0 0 3 3 3 0 Initiation control protein YabA Sec1 PF00995.23 RKO98565.1 - 1.2e-84 285.6 0.0 2e-84 284.9 0.0 1.3 1 1 0 1 1 1 1 Sec1 family Pyrophosphatase PF00719.19 RKO98566.1 - 3.2e-52 176.6 0.1 4e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2863 PF11062.8 RKO98567.1 - 0.058 11.8 1.3 0.057 11.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Kinesin PF00225.23 RKO98568.1 - 1.7e-97 326.4 0.0 2e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO98568.1 - 1.3e-14 54.3 0.1 4.9e-12 46.0 0.1 2.6 1 1 0 1 1 1 1 Microtubule binding Synaptobrevin PF00957.21 RKO98569.1 - 0.13 12.0 1.4 0.43 10.4 1.4 1.9 1 0 0 1 1 1 0 Synaptobrevin DUF4538 PF15061.6 RKO98569.1 - 0.31 10.8 5.3 0.17 11.7 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Ist1 PF03398.14 RKO98571.1 - 4.9e-60 202.2 0.4 5.5e-60 202.0 0.4 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Sortilin-Vps10 PF15902.5 RKO98572.1 - 7.8e-49 166.7 0.0 8.7e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 RKO98572.1 - 0.0053 16.6 0.2 0.32 11.2 0.1 2.6 2 0 0 2 2 2 1 BNR/Asp-box repeat Y_phosphatase3 PF13350.6 RKO98573.1 - 2.3e-30 106.3 0.0 2.6e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKO98573.1 - 0.0078 15.8 0.1 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 RKO98573.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 RKO98573.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain GAS PF13851.6 RKO98574.1 - 5e-55 186.0 18.7 5e-55 186.0 18.7 4.1 3 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding F_actin_cap_B PF01115.17 RKO98576.1 - 1.6e-99 332.3 0.0 1.9e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.25 RKO98579.1 - 1.2e-28 100.2 0.0 1.2e-22 80.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98579.1 - 2.4e-17 63.1 0.0 2.8e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RKO98579.1 - 9.8e-06 25.7 1.3 0.0016 18.4 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RKO98579.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RKO98579.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MFS_1 PF07690.16 RKO98580.1 - 1.8e-08 33.7 58.8 5.4e-06 25.6 9.6 3.7 2 2 1 3 3 3 3 Major Facilitator Superfamily G0-G1_switch_2 PF15103.6 RKO98580.1 - 0.3 11.5 0.9 11 6.5 0.2 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 SUIM_assoc PF16619.5 RKO98580.1 - 0.73 9.9 7.5 1.5 9.0 7.5 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 RKO98580.1 - 2 8.0 5.2 3.4 7.2 5.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF4611 PF15387.6 RKO98581.1 - 0.0018 18.5 6.8 0.0049 17.1 6.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 RKO98581.1 - 0.0099 15.6 15.0 0.0099 15.6 15.0 1.9 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 RKO98581.1 - 0.02 14.8 0.7 0.024 14.6 0.7 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 RKO98581.1 - 0.05 11.7 17.6 0.061 11.4 17.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 RKO98581.1 - 0.15 12.3 14.3 0.41 10.8 14.3 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 RKO98581.1 - 0.21 10.9 19.8 0.39 10.0 19.8 1.3 1 0 0 1 1 1 0 NOA36 protein GP67 PF17634.2 RKO98581.1 - 0.23 11.9 24.0 0.46 10.9 24.0 1.4 1 0 0 1 1 1 0 Gene product 67 MAM33 PF02330.16 RKO98581.1 - 0.26 11.2 1.9 0.37 10.7 1.9 1.1 1 0 0 1 1 1 0 Mitochondrial glycoprotein CENP-B_dimeris PF09026.10 RKO98581.1 - 0.36 11.2 26.4 0.94 9.9 26.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain eIF-3c_N PF05470.12 RKO98581.1 - 0.47 8.7 4.6 0.6 8.3 4.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 RKO98581.1 - 0.67 8.1 12.3 0.85 7.8 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RKO98581.1 - 0.78 9.8 11.0 1.3 9.0 11.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RKO98581.1 - 0.81 7.9 11.1 1.1 7.5 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 RKO98581.1 - 1.1 7.0 6.7 1.3 6.7 6.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 RKO98581.1 - 1.7 7.9 21.2 2.5 7.4 21.2 1.2 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 RKO98581.1 - 2.5 8.1 10.6 0.2 11.7 5.9 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal SDA1 PF05285.12 RKO98581.1 - 2.6 7.4 17.0 3.5 7.0 17.0 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 RKO98581.1 - 2.8 6.4 10.1 3.5 6.1 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop25 PF09805.9 RKO98581.1 - 3.3 8.2 5.9 11 6.5 5.9 1.7 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Apt1 PF10351.9 RKO98581.1 - 7.7 5.3 8.8 10 4.8 8.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFB6 PF17110.5 RKO98581.1 - 8.1 6.1 7.9 1 9.1 4.0 1.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Glyco_hydro_16 PF00722.21 RKO98582.1 - 4.9e-07 29.4 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RPN1_RPN2_N PF17781.1 RKO98583.1 - 2.8e-117 391.5 0.2 6.6e-117 390.3 0.0 1.7 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 RKO98583.1 - 6.8e-31 106.1 0.0 1.2e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 RKO98583.1 - 7.9e-24 82.8 17.6 7.1e-07 29.4 0.1 8.0 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RKO98583.1 - 2.2e-07 31.2 12.4 0.00056 20.2 1.7 6.3 6 2 2 8 8 8 4 HEAT repeats HEAT PF02985.22 RKO98583.1 - 0.082 13.2 1.1 1.8e+02 2.8 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat Myb_DNA-binding PF00249.31 RKO98585.1 - 1.8e-26 92.1 7.5 3.3e-13 49.6 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKO98585.1 - 4.9e-17 61.9 2.3 1e-08 35.3 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RKO98585.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Nuc_sug_transp PF04142.15 RKO98586.1 - 2.8e-111 371.6 6.6 3.5e-111 371.4 6.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RKO98586.1 - 8.3e-05 22.8 0.7 8.3e-05 22.8 0.7 2.5 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 RKO98586.1 - 0.00011 21.5 15.9 0.034 13.3 7.1 2.3 1 1 0 2 2 2 2 UAA transporter family PUNUT PF16913.5 RKO98586.1 - 0.063 12.5 15.2 0.036 13.3 11.9 2.1 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport TPT PF03151.16 RKO98586.1 - 0.22 10.9 12.4 0.023 14.0 1.9 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family LRR_6 PF13516.6 RKO98587.1 - 3.5e-06 26.6 0.0 0.9 9.8 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat SNF2_N PF00176.23 RKO98588.1 - 3.7e-37 127.9 0.2 4.7e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO98588.1 - 2.9e-14 53.3 0.0 5.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain p450 PF00067.22 RKO98589.1 - 8.9e-68 229.1 0.0 1.2e-67 228.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3375 PF11855.8 RKO98589.1 - 0.11 11.4 0.1 6.1 5.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) SH3_9 PF14604.6 RKO98590.1 - 8.6e-08 31.9 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO98590.1 - 1.5e-07 30.9 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Adeno_E3_CR2 PF02439.15 RKO98590.1 - 0.0012 18.5 1.6 0.0022 17.7 1.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 RKO98590.1 - 0.018 13.8 0.1 0.025 13.3 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SH3_2 PF07653.17 RKO98590.1 - 0.043 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain EphA2_TM PF14575.6 RKO98590.1 - 0.052 14.4 0.1 0.12 13.3 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 RKO98590.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 RKO98590.1 - 0.15 11.5 7.6 0.27 10.7 7.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 RKO98590.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4381 PF14316.6 RKO98590.1 - 0.28 11.4 0.3 0.47 10.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CMAS PF02353.20 RKO98592.1 - 7.9e-64 215.6 0.5 1e-63 215.2 0.5 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 RKO98592.1 - 5.1e-14 52.7 0.1 9.5e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO98592.1 - 2.1e-13 50.4 0.0 4.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO98592.1 - 1.6e-12 47.9 0.0 3.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO98592.1 - 2.7e-07 31.2 0.0 4.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO98592.1 - 1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO98592.1 - 0.00022 20.8 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 RKO98592.1 - 0.00032 20.5 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 RKO98592.1 - 0.0004 20.5 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 RKO98592.1 - 0.0031 17.1 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 RKO98592.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 RKO98592.1 - 0.02 13.5 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 RKO98592.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 RKO98592.1 - 0.028 13.9 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 RKO98592.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 RKO98592.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Hexokinase_2 PF03727.16 RKO98595.1 - 1.8e-81 273.1 0.0 2.7e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RKO98595.1 - 6.5e-69 231.8 0.0 8.9e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase TBP PF00352.21 RKO98596.1 - 1.6e-67 223.5 0.2 8.5e-33 112.2 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 RKO98596.1 - 4.7e-05 23.4 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 RKO98596.1 - 0.12 12.1 0.1 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Sld5 PF05916.11 RKO98597.1 - 1.7e-08 34.9 0.0 2.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein RNA_pol_N PF01194.17 RKO98598.1 - 1.2e-32 111.9 0.4 1.3e-32 111.8 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit HSP70 PF00012.20 RKO98599.1 - 1.2e-79 268.1 0.1 1.4e-79 267.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKO98599.1 - 2.4e-12 46.3 0.0 7.7e-12 44.7 0.0 1.7 2 1 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 RKO98599.1 - 0.12 10.9 0.0 13 4.3 0.0 2.5 3 0 0 3 3 3 0 Actin DUF641 PF04859.12 RKO98600.1 - 0.00061 20.1 19.0 0.0079 16.5 4.2 3.5 2 1 1 3 3 3 2 Plant protein of unknown function (DUF641) SCP1201-deam PF14428.6 RKO98600.1 - 0.089 12.7 5.2 0.26 11.2 5.2 1.8 1 0 0 1 1 1 0 SCP1.201-like deaminase DUF5320 PF17253.2 RKO98600.1 - 1.4 10.0 3.2 20 6.3 1.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) PKcGMP_CC PF16808.5 RKO98600.1 - 6.5 6.7 15.6 0.25 11.2 1.5 3.6 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HgmA PF04209.13 RKO98602.1 - 3.7e-194 645.3 0.1 4.1e-194 645.1 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Yuri_gagarin PF15934.5 RKO98603.1 - 0.04 13.8 3.9 0.069 13.0 3.9 1.4 1 0 0 1 1 1 0 Yuri gagarin Lebercilin PF15619.6 RKO98603.1 - 0.18 11.4 22.6 0.53 9.9 10.6 2.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 RKO98603.1 - 0.38 10.6 1.9 7.8 6.4 0.6 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 RKO98603.1 - 0.57 10.3 8.4 1.6 8.8 2.0 2.4 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component WXG100 PF06013.12 RKO98603.1 - 1.5 9.1 9.9 0.2 11.9 2.8 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG FAM76 PF16046.5 RKO98603.1 - 3.8 6.8 11.1 6.7 6.0 11.1 1.3 1 0 0 1 1 1 0 FAM76 protein Ctr PF04145.15 RKO98604.1 - 1.5e-26 93.8 0.7 1.9e-26 93.5 0.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family RPN2_C PF18004.1 RKO98605.1 - 1e-42 145.8 0.1 1.9e-42 144.9 0.1 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 RKO98605.1 - 4.7e-41 137.2 14.7 4.5e-08 33.1 0.0 8.6 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RKO98605.1 - 5.9e-20 71.5 1.3 1e-14 54.7 0.0 4.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 RKO98605.1 - 4e-07 29.7 1.2 0.052 13.8 0.1 5.4 5 0 0 5 5 4 1 HEAT repeat HEAT_EZ PF13513.6 RKO98605.1 - 2.8e-05 24.5 1.1 6.8 7.3 0.0 5.1 6 0 0 6 6 5 1 HEAT-like repeat IBN_N PF03810.19 RKO98605.1 - 0.0034 17.3 0.1 41 4.2 0.0 3.8 2 1 1 3 3 3 0 Importin-beta N-terminal domain Cnd1 PF12717.7 RKO98605.1 - 0.0038 17.3 0.1 1.7 8.7 0.0 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKO98605.1 - 0.016 13.8 0.2 4.5 5.7 0.0 3.3 3 0 0 3 3 3 0 Adaptin N terminal region Arm PF00514.23 RKO98605.1 - 0.068 13.2 0.3 7 6.9 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Clathrin_H_link PF13838.6 RKO98605.1 - 0.088 12.7 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 Clathrin-H-link HEAT_PBS PF03130.16 RKO98605.1 - 0.12 13.2 0.0 21 6.2 0.0 3.6 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat Vfa1 PF08432.10 RKO98605.1 - 1.8 8.9 4.8 6.9 7.0 1.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PRELI PF04707.14 RKO98607.1 - 4.2e-36 124.1 0.0 4.8e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family SNF2_N PF00176.23 RKO98608.1 - 3.8e-61 206.7 0.5 1.1e-60 205.2 0.3 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO98608.1 - 2.9e-21 75.9 0.0 6.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 RKO98608.1 - 6.8e-20 70.7 0.0 3.8e-10 39.5 0.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 RKO98608.1 - 2.9e-14 53.3 2.9 2.9e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 RKO98608.1 - 5.8e-10 39.4 0.0 3.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RKO98608.1 - 4.8e-09 35.8 0.4 8.7e-09 34.9 0.4 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 RKO98608.1 - 5.3e-05 22.6 0.0 9.9e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CDH1_2_SANT_HL1 PF18375.1 RKO98608.1 - 0.0039 17.8 0.0 0.018 15.7 0.0 2.1 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 Cdh1_DBD_1 PF18196.1 RKO98608.1 - 0.026 14.8 0.0 0.026 14.8 0.0 4.5 5 1 0 5 5 5 0 Chromodomain helicase DNA-binding domain 1 CHDCT2 PF08074.11 RKO98608.1 - 0.062 13.5 3.3 0.099 12.8 0.0 2.9 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DUF3006 PF11213.8 RKO98608.1 - 0.79 10.0 4.9 0.34 11.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Sporozoite_P67 PF05642.11 RKO98608.1 - 6.5 4.7 6.6 13 3.7 6.5 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Alpha-2-MRAP_C PF06401.11 RKO98608.1 - 8.4 6.3 9.6 8.1 6.3 0.2 3.5 3 0 0 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain LexA_DNA_bind PF01726.16 RKO98609.1 - 0.047 13.5 0.4 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 LexA DNA binding domain DnaJ PF00226.31 RKO98610.1 - 3.2e-13 49.6 0.2 1.1e-12 47.8 0.2 1.8 1 1 0 1 1 1 1 DnaJ domain Iso_dh PF00180.20 RKO98611.1 - 1.3e-75 254.7 0.0 1.6e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.32 RKO98612.1 - 9.1e-05 23.2 0.2 1.7 9.7 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98612.1 - 0.00034 20.9 0.0 0.14 12.5 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO98612.1 - 0.016 14.2 0.6 1.1 8.1 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein tRNA-synt_1b PF00579.25 RKO98613.1 - 4.8e-60 203.3 0.0 3.2e-59 200.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DNA_pol_phi PF04931.13 RKO98615.1 - 0.14 10.2 24.1 0.12 10.4 24.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 RKO98615.1 - 1.3 7.1 17.0 1.1 7.3 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 RKO98615.1 - 1.8 6.8 20.0 1.9 6.7 20.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RKO98615.1 - 2.9 7.2 17.7 2.8 7.3 17.7 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 RKO98615.1 - 3.2 7.6 14.6 3.5 7.5 14.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TFB6 PF17110.5 RKO98615.1 - 3.5 7.4 9.5 3.2 7.5 9.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4637 PF15470.6 RKO98615.1 - 3.8 7.2 8.0 3.9 7.2 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Sporozoite_P67 PF05642.11 RKO98615.1 - 4.6 5.2 10.4 4.4 5.3 10.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Utp14 PF04615.13 RKO98615.1 - 7.7 4.9 13.5 8.2 4.9 13.5 1.3 1 0 0 1 1 1 0 Utp14 protein Mito_carr PF00153.27 RKO98616.1 - 7.1e-57 189.3 1.8 1.2e-18 66.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 RKO98616.1 - 3.2e-06 26.3 0.0 0.00044 19.6 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 RKO98616.1 - 2.8e-05 24.5 0.0 0.03 14.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RKO98616.1 - 6.6e-05 22.2 0.6 0.00015 21.1 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 RKO98616.1 - 0.00054 19.8 0.0 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RKO98616.1 - 0.0051 16.7 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain Complex1_LYR PF05347.15 RKO98618.1 - 5.2e-09 36.0 0.3 9e-09 35.3 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 RKO98618.1 - 1.9e-06 28.5 0.1 2.7e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like WD40 PF00400.32 RKO98619.1 - 4e-38 128.7 13.6 1.4e-09 38.4 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98619.1 - 1.3e-19 70.3 0.6 0.0015 18.7 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO98619.1 - 6.3e-06 25.4 3.6 0.2 10.6 0.1 4.7 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2415 PF10313.9 RKO98619.1 - 0.00016 21.5 0.1 0.31 11.0 0.0 3.9 4 0 0 4 4 4 1 Uncharacterised protein domain (DUF2415) eIF2A PF08662.11 RKO98619.1 - 0.0014 18.5 0.0 0.025 14.4 0.0 2.4 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 RKO98619.1 - 0.0044 15.4 0.0 0.034 12.5 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 RKO98619.1 - 0.0061 15.9 0.1 1.4 8.2 0.0 3.2 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 RKO98619.1 - 0.014 13.9 0.3 1.7 7.1 0.1 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain Peptidase_S9 PF00326.21 RKO98619.1 - 0.018 14.5 0.2 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family WD40_like PF17005.5 RKO98619.1 - 0.032 13.5 0.0 5.6 6.2 0.0 3.1 3 1 1 4 4 4 0 WD40-like domain Nucleoporin_N PF08801.11 RKO98619.1 - 0.14 10.9 0.0 0.36 9.5 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.8 RKO98619.1 - 0.18 10.4 0.1 0.18 10.4 0.1 2.0 2 2 1 3 3 3 0 Nucleoporin Nup120/160 Aminotran_1_2 PF00155.21 RKO98620.1 - 4.9e-89 299.0 0.0 5.6e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sybindin PF04099.12 RKO98621.1 - 1e-43 148.7 0.0 1.2e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RKO98621.1 - 5.5e-07 29.8 0.0 8.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Piwi PF02171.17 RKO98622.1 - 2.9e-79 266.4 0.0 4e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 RKO98622.1 - 5.5e-15 54.8 0.1 1.1e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 RKO98622.1 - 5.4e-12 45.7 0.0 9.3e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 RKO98622.1 - 2.8e-06 27.5 0.0 7.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 RKO98622.1 - 0.014 15.8 0.0 0.062 13.6 0.0 2.2 2 0 0 2 2 2 0 Argonaute linker 2 domain Ery_res_leader2 PF08057.11 RKO98622.1 - 0.35 11.4 1.9 1.1 9.9 0.3 2.7 2 0 0 2 2 2 0 Erythromycin resistance leader peptide DUF4381 PF14316.6 RKO98623.1 - 0.013 15.7 4.0 0.022 15.0 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LPG_synthase_TM PF03706.13 RKO98623.1 - 0.094 12.2 1.2 0.11 12.0 1.2 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Phage_Gp23 PF10669.9 RKO98623.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Adeno_E3_CR2 PF02439.15 RKO98623.1 - 0.13 12.0 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 RKO98623.1 - 1.3 8.9 5.9 25 4.8 5.9 2.2 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DFRP_C PF16543.5 RKO98624.1 - 2.7e-23 82.3 0.8 2.7e-23 82.3 0.8 3.8 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 RKO98624.1 - 8.7e-08 31.9 1.1 8.7e-08 31.9 1.1 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RKO98624.1 - 1.4e-06 29.0 14.9 0.00033 21.3 4.0 4.1 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 RKO98624.1 - 1.2e-05 25.2 7.7 1.2e-05 25.2 7.7 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 RKO98624.1 - 0.00014 21.6 10.0 0.00042 20.0 2.4 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 RKO98624.1 - 0.0054 16.9 1.0 0.12 12.6 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 RKO98624.1 - 0.009 16.5 12.5 0.029 14.8 4.9 2.9 2 1 0 2 2 2 1 RNA-binding, Nab2-type zinc finger DUF1178 PF06676.11 RKO98624.1 - 4.4 7.7 16.3 1.6 9.1 5.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1178) Peptidase_M20 PF01546.28 RKO98625.1 - 2.7e-34 118.7 0.0 2.4e-33 115.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RKO98625.1 - 7.1e-09 35.6 0.0 2.6e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RKO98625.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF2939 PF11159.8 RKO98625.1 - 0.12 12.8 0.2 0.54 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Oxidored_q6 PF01058.22 RKO98626.1 - 6.5e-22 77.8 0.0 9.5e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tmemb_14 PF03647.13 RKO98626.1 - 0.064 14.0 0.1 0.12 13.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C HMG_box PF00505.19 RKO98628.1 - 6.8e-18 64.9 0.8 1e-17 64.3 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO98628.1 - 8.1e-06 26.3 0.2 1.3e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain Drf_GBD PF06371.13 RKO98629.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Bmt2 PF11968.8 RKO98630.1 - 1.4e-54 185.2 0.0 1.8e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 RKO98630.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0220 PF05255.11 RKO98631.1 - 1.4e-37 128.8 2.9 1.5e-37 128.7 2.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Membr_traf_MHD PF10540.9 RKO98632.1 - 2e-14 54.0 0.5 4.6e-06 26.9 0.0 2.1 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain Branch PF02485.21 RKO98633.1 - 3.7e-25 88.9 0.2 6.6e-25 88.0 0.2 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DinB PF05163.12 RKO98633.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 DinB family Utp12 PF04003.12 RKO98634.1 - 7.2e-17 61.7 0.7 1.2e-16 60.9 0.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Tub_N PF16322.5 RKO98634.1 - 0.039 14.4 12.0 0.059 13.8 9.8 2.2 2 0 0 2 2 2 0 Tubby N-terminal CYSTM PF12734.7 RKO98636.1 - 1e-10 41.7 17.9 1e-10 41.7 17.9 3.5 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Arabinose_Iso_C PF11762.8 RKO98637.1 - 0.016 15.0 0.2 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain DUF676 PF05057.14 RKO98639.1 - 2.5e-21 76.2 0.0 7e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 RKO98639.1 - 0.00015 21.6 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 RKO98639.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Flu_NS1 PF00600.19 RKO98639.1 - 0.49 9.9 1.1 5.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Influenza non-structural protein (NS1) LRR_8 PF13855.6 RKO98640.1 - 8.4e-08 31.9 0.1 1.4e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 RKO98640.1 - 2.7e-06 27.6 0.5 0.0046 17.3 0.0 2.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKO98640.1 - 0.068 13.8 0.1 13 6.8 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 RKO98640.1 - 0.17 12.0 0.1 23 5.4 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat GHMP_kinases_N PF00288.26 RKO98641.1 - 2.4e-15 56.5 3.3 9.5e-15 54.6 3.3 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RKO98641.1 - 1.6e-06 28.4 0.2 5.2e-06 26.7 0.2 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Pro_dh PF01619.18 RKO98642.1 - 5.2e-70 236.3 0.0 6.2e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Tmemb_161AB PF10268.9 RKO98642.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF1295 PF06966.12 RKO98643.1 - 2.8e-25 89.2 4.2 2.8e-25 89.2 4.2 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1295) DEAD PF00270.29 RKO98644.1 - 4.2e-39 134.1 0.0 6.2e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98644.1 - 1.6e-26 92.9 0.1 2.3e-25 89.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98644.1 - 2.4e-08 34.1 0.0 5e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RKO98644.1 - 0.00081 19.7 2.0 0.018 15.3 2.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO98644.1 - 0.00086 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RKO98644.1 - 0.12 12.3 0.2 1.1 9.2 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Ribosomal_S8e PF01201.22 RKO98645.1 - 1.8e-50 170.7 0.2 3.1e-50 169.9 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e DUF4050 PF13259.6 RKO98648.1 - 2.8e-05 24.5 0.6 0.00017 22.0 0.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) CinA PF02464.17 RKO98648.1 - 0.013 15.1 0.9 0.021 14.4 0.9 1.3 1 0 0 1 1 1 0 Competence-damaged protein SRP54 PF00448.22 RKO98649.1 - 8.1e-49 165.9 0.8 8.9e-38 129.9 0.2 2.1 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain MeaB PF03308.16 RKO98649.1 - 1.6e-10 40.4 0.1 2.5e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 RKO98649.1 - 1.2e-05 25.2 0.4 2.5e-05 24.1 0.4 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO98649.1 - 0.00035 20.9 0.0 0.0072 16.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 RKO98649.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 RKO98649.1 - 0.0017 17.9 0.0 0.0037 16.8 0.0 1.5 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 RKO98649.1 - 0.0021 17.3 0.3 0.044 13.0 0.1 2.2 1 1 1 2 2 2 1 Anion-transporting ATPase CbiA PF01656.23 RKO98649.1 - 0.0024 17.9 0.0 0.02 15.0 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 RKO98649.1 - 0.0051 17.2 0.6 0.012 16.0 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_31 PF13614.6 RKO98649.1 - 0.014 15.3 0.0 0.05 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKO98649.1 - 0.015 14.6 0.0 0.042 13.1 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 RKO98649.1 - 0.035 14.2 0.4 0.17 12.0 0.4 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF1640 PF07798.11 RKO98650.1 - 2.1e-34 119.1 6.0 2.4e-34 118.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 RKO98650.1 - 8.7e-05 22.6 3.1 0.0006 19.9 0.3 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 RKO98650.1 - 0.00023 21.2 3.8 0.11 12.5 0.2 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 RKO98650.1 - 0.0025 15.9 1.5 0.0028 15.7 1.5 1.0 1 0 0 1 1 1 1 Prominin LppA PF16708.5 RKO98650.1 - 0.0026 17.7 0.9 0.66 9.9 0.0 2.6 1 1 2 3 3 3 1 Lipoprotein confined to pathogenic Mycobacterium Apolipoprotein PF01442.18 RKO98650.1 - 0.0067 16.3 8.6 0.015 15.2 8.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CPSF73-100_C PF11718.8 RKO98650.1 - 0.013 15.1 0.6 0.12 11.9 0.1 2.0 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Es2 PF09751.9 RKO98650.1 - 0.021 14.6 1.6 0.025 14.4 1.6 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 Exonuc_VII_L PF02601.15 RKO98650.1 - 0.022 14.4 1.7 0.028 14.0 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoLp-III PF07464.11 RKO98650.1 - 0.026 14.6 0.8 0.11 12.6 0.8 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3958 PF13125.6 RKO98650.1 - 0.05 13.8 8.3 0.32 11.2 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) HetR_C PF18460.1 RKO98650.1 - 0.057 13.4 1.2 0.17 11.9 0.7 2.0 1 1 1 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain COG2 PF06148.11 RKO98650.1 - 0.067 13.3 6.1 2.7 8.1 2.4 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lectin_N PF03954.14 RKO98650.1 - 0.076 12.8 0.8 0.2 11.4 0.7 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Oxygenase-NA PF09859.9 RKO98650.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA adh_short PF00106.25 RKO98650.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.5 1 1 0 2 2 2 0 short chain dehydrogenase CdvA PF18822.1 RKO98650.1 - 0.14 12.0 6.3 0.22 11.4 1.0 2.7 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DUF1451 PF07295.11 RKO98650.1 - 0.16 12.0 3.3 0.55 10.3 2.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF1664 PF07889.12 RKO98650.1 - 0.17 11.9 5.2 0.84 9.7 2.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 RKO98650.1 - 0.18 12.4 7.5 3.8 8.2 0.5 2.7 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIC PF04977.15 RKO98650.1 - 0.45 10.3 8.6 0.096 12.5 1.9 2.6 2 2 1 3 3 3 0 Septum formation initiator HSCB_C PF07743.13 RKO98650.1 - 0.47 11.0 8.9 0.46 11.0 0.6 2.7 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Fzo_mitofusin PF04799.13 RKO98650.1 - 0.6 9.7 3.9 0.86 9.1 0.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF3450 PF11932.8 RKO98650.1 - 0.73 9.1 9.1 6.2 6.0 9.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) XhlA PF10779.9 RKO98650.1 - 1.5 9.1 6.7 9.1 6.6 0.4 2.6 2 1 0 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 RKO98650.1 - 2.1 8.8 8.4 14 6.2 0.3 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CorA PF01544.18 RKO98650.1 - 3.1 7.0 10.5 6.8 5.9 1.2 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HalX PF08663.10 RKO98650.1 - 6 7.3 12.6 19 5.7 2.0 3.8 2 2 0 2 2 2 0 HalX domain Formyl_trans_N PF00551.19 RKO98651.1 - 7.9e-22 77.9 0.1 8.5e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase Aconitase PF00330.20 RKO98653.1 - 6.3e-103 345.2 0.8 8.8e-102 341.5 0.8 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RKO98653.1 - 4.9e-19 68.9 0.0 9.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Thiolase_N PF00108.23 RKO98654.1 - 3.7e-89 298.5 3.0 5e-89 298.1 3.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKO98654.1 - 9e-42 141.6 2.0 1.9e-41 140.5 0.8 2.1 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RKO98654.1 - 0.00014 21.5 2.2 0.0062 16.1 1.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 RKO98654.1 - 0.056 13.6 0.1 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RCC1 PF00415.18 RKO98655.1 - 4.7e-18 65.5 6.8 6.7e-05 23.4 0.0 6.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKO98655.1 - 3.3e-12 45.9 32.3 0.0001 22.0 0.7 6.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_M16_M PF16187.5 RKO98657.1 - 7.7e-70 235.4 0.0 1.2e-69 234.8 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RKO98657.1 - 2e-41 141.4 0.0 3.8e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RKO98657.1 - 2.2e-32 112.5 0.0 3.4e-22 79.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ribonuc_L-PSP PF01042.21 RKO98658.1 - 4.1e-44 149.5 0.4 4.6e-44 149.3 0.4 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cu-oxidase_3 PF07732.15 RKO98659.1 - 2.5e-35 121.0 0.8 1.1e-32 112.5 1.3 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 RKO98659.1 - 1.6e-31 108.9 8.8 9.1e-31 106.4 0.1 3.5 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 RKO98659.1 - 2e-23 83.3 1.0 1.7e-22 80.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase TFIIF_alpha PF05793.12 RKO98659.1 - 0.82 8.2 2.1 1.1 7.7 2.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FTR1 PF03239.14 RKO98660.1 - 1.3e-39 136.2 15.5 7.9e-36 123.8 12.5 2.2 2 0 0 2 2 2 2 Iron permease FTR1 family PWWP PF00855.17 RKO98662.1 - 6e-05 23.4 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 PWWP domain TatD_DNase PF01026.21 RKO98663.1 - 5.6e-44 150.4 0.0 7.8e-34 117.2 0.0 2.1 2 0 0 2 2 2 2 TatD related DNase ARID PF01388.21 RKO98664.1 - 3.6e-11 43.6 0.0 3.6e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF2126 PF09899.9 RKO98664.1 - 0.048 11.7 6.9 0.069 11.2 6.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Presenilin PF01080.17 RKO98664.1 - 2 7.1 10.7 4.2 6.0 10.7 1.4 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 RKO98664.1 - 2.4 8.2 6.6 0.53 10.3 3.1 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 RKO98664.1 - 2.8 7.3 9.3 4.4 6.7 9.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 RKO98664.1 - 9.9 6.1 15.0 26 4.7 15.0 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Maf1 PF09174.10 RKO98665.1 - 1.6e-36 126.1 0.0 2.4e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator zf-met2 PF12907.7 RKO98665.1 - 0.11 12.6 0.4 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding tRNA-synt_2 PF00152.20 RKO98666.1 - 4.1e-77 259.3 0.0 5.5e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RKO98666.1 - 8.9e-10 38.4 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RKO98666.1 - 2.3e-09 37.1 0.1 0.00036 20.1 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ASH PF15780.5 RKO98666.1 - 0.038 14.2 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Mpp10 PF04006.12 RKO98666.1 - 1.1 7.6 11.6 1.6 7.1 11.6 1.1 1 0 0 1 1 1 0 Mpp10 protein UPF0160 PF03690.13 RKO98667.1 - 5.9e-122 407.3 0.0 6.7e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) CCDC66 PF15236.6 RKO98668.1 - 0.021 14.7 48.7 0.067 13.0 40.4 3.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 66 Nbs1_C PF08599.10 RKO98668.1 - 1.9 8.7 3.2 3.8 7.7 1.8 2.3 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 YjbH PF06082.11 RKO98668.1 - 6.5 5.4 9.6 12 4.6 9.6 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH zf-MIZ PF02891.20 RKO98670.1 - 3.5e-13 49.1 1.5 6.4e-13 48.2 1.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 RKO98670.1 - 3.2e-07 30.8 0.0 6.5e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 PINIT domain SAP PF02037.27 RKO98670.1 - 0.00067 19.4 1.3 0.0014 18.3 1.3 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 RKO98670.1 - 0.0066 16.2 0.3 0.011 15.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit VPS9 PF02204.18 RKO98671.1 - 8.1e-23 80.6 0.1 1.3e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 RKO98671.1 - 0.24 11.7 0.0 0.49 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) ACBP PF00887.19 RKO98672.1 - 4.5e-27 94.1 0.2 5.3e-27 93.9 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 RKO98672.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 FERM central domain ASFV_J13L PF05568.11 RKO98673.1 - 0.0021 17.9 44.6 0.82 9.4 1.5 6.0 1 1 2 3 3 3 2 African swine fever virus J13L protein Tic110 PF16940.5 RKO98674.1 - 0.098 11.1 0.3 0.21 10.1 0.3 1.5 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF3784 PF12650.7 RKO98674.1 - 0.17 12.1 0.9 0.31 11.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) 3HCDH_N PF02737.18 RKO98675.1 - 3.7e-56 189.8 3.0 6.1e-56 189.1 3.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RKO98675.1 - 1.4e-33 115.3 0.0 3.1e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 RKO98675.1 - 0.0049 17.1 0.7 0.0089 16.3 0.7 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 RKO98675.1 - 0.023 14.3 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 RKO98675.1 - 0.042 14.0 2.0 0.1 12.8 2.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 RKO98675.1 - 0.043 13.1 0.2 0.061 12.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RKO98675.1 - 0.15 11.2 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 RKO98675.1 - 0.75 9.9 4.5 0.65 10.1 0.8 2.3 1 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 RKO98675.1 - 1 9.5 3.4 2.8 8.1 2.3 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Amidohydro_2 PF04909.14 RKO98676.1 - 7.7e-11 42.3 0.8 1.5e-10 41.3 0.3 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 RKO98676.1 - 1.6e-09 37.6 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Sipho_Gp157 PF05565.11 RKO98676.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 PRKCSH PF07915.13 RKO98677.1 - 8e-09 36.4 0.0 1.8e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Pro_CA PF00484.19 RKO98678.1 - 4.3e-44 150.6 0.4 5.4e-44 150.2 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SSXT PF05030.12 RKO98678.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Glyco_hydro_15 PF00723.21 RKO98679.1 - 1.1e-57 195.8 0.3 2e-57 195.0 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Ribosomal_L14 PF00238.19 RKO98680.1 - 6.9e-36 123.0 0.0 8.2e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 RKO98680.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal HAUS4 PF14735.6 RKO98681.1 - 6.9e-06 25.9 0.1 1.1e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 AbiJ_NTD5 PF18865.1 RKO98681.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 TPR_MLP1_2 PF07926.12 RKO98681.1 - 0.42 10.7 1.6 4.4 7.4 0.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 RKO98682.1 - 4.2e-40 137.8 0.0 3.7e-32 111.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98682.1 - 1.4e-16 60.6 0.0 2.8e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO98682.1 - 0.00045 19.6 0.0 0.00094 18.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO98682.1 - 0.0071 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.23 RKO98683.1 - 8e-34 116.1 0.2 3.7e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RKO98683.1 - 3.1e-17 62.8 0.1 5.4e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 RKO98683.1 - 0.0069 16.8 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin C-terminal domain Cg6151-P PF10233.9 RKO98687.1 - 2.3e-25 89.1 13.6 2.8e-25 88.8 13.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Phage_holin_3_6 PF07332.11 RKO98687.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PRA1 PF03208.19 RKO98687.1 - 1.2 8.8 12.4 2.9 7.5 12.4 1.6 1 1 0 1 1 1 0 PRA1 family protein Ac76 PF05814.11 RKO98687.1 - 4.9 7.2 9.6 0.38 10.8 0.3 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Cyt_b-c1_8 PF10890.8 RKO98689.1 - 0.059 13.8 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 IDEAL PF08858.10 RKO98689.1 - 0.19 11.5 0.1 0.64 9.8 0.1 1.9 1 0 0 1 1 1 0 IDEAL domain TPR_2 PF07719.17 RKO98692.1 - 1.8e-21 74.5 30.4 0.0011 18.9 0.1 8.8 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 RKO98692.1 - 2.1e-16 59.2 31.1 0.0042 17.8 0.3 8.2 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98692.1 - 2.4e-16 58.7 20.5 0.0062 16.3 0.0 7.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 RKO98692.1 - 3.3e-16 59.6 19.4 0.0025 18.3 0.1 7.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 RKO98692.1 - 8.8e-16 56.7 11.3 0.13 12.5 0.0 8.7 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 RKO98692.1 - 2.3e-15 57.0 29.9 0.0015 19.1 0.4 7.4 5 2 1 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 RKO98692.1 - 1.8e-12 46.7 5.5 0.0011 18.7 0.3 6.9 4 2 3 7 7 7 3 TPR repeat TPR_17 PF13431.6 RKO98692.1 - 4.2e-10 39.3 12.1 0.26 11.7 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 RKO98692.1 - 2e-08 33.7 13.5 0.0048 16.8 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO98692.1 - 2.5e-07 30.9 23.5 9.5e-05 22.6 1.1 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 RKO98692.1 - 3.4e-07 30.5 30.6 0.16 12.7 0.1 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 RKO98692.1 - 3.6e-05 23.8 25.2 0.075 13.2 0.1 6.1 3 2 4 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO98692.1 - 0.00027 21.1 15.4 1.7 8.9 0.1 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 RKO98692.1 - 0.01 14.9 0.1 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 RKO98692.1 - 0.018 15.6 3.3 0.018 15.6 3.3 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 RKO98692.1 - 0.031 14.0 0.1 5.5 6.7 0.0 3.4 2 2 1 3 3 3 0 26S proteasome subunit RPN7 BTAD PF03704.17 RKO98692.1 - 0.21 12.0 13.7 1.1 9.7 0.1 4.3 4 1 1 5 5 4 0 Bacterial transcriptional activator domain AA_permease PF00324.21 RKO98693.1 - 3.9e-81 273.1 34.3 1.2e-80 271.4 34.3 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 RKO98693.1 - 2.3e-34 118.9 26.5 2.8e-34 118.7 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease MIG-14_Wnt-bd PF06664.12 RKO98693.1 - 0.0088 15.3 0.2 0.025 13.8 0.2 1.8 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Clathrin PF00637.20 RKO98694.1 - 2.6e-13 50.1 0.0 8.8e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 RKO98694.1 - 0.088 13.1 0.1 5.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SRPRB PF09439.10 RKO98695.1 - 1.2e-24 86.8 0.0 2.1e-23 82.7 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 RKO98695.1 - 5.5e-10 39.0 0.0 3.5e-08 33.1 0.0 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO98695.1 - 0.00075 19.1 0.0 0.012 15.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKO98695.1 - 0.079 12.9 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Lys_export PF03956.13 RKO98695.1 - 0.099 12.2 0.0 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 Lysine exporter LysO Herpes_capsid PF06112.11 RKO98695.1 - 0.25 11.4 0.2 0.25 11.4 0.2 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PMI_typeI PF01238.21 RKO98696.1 - 2.7e-93 313.1 0.0 3.5e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 RKO98696.1 - 2.7e-05 23.8 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 RKO98696.1 - 0.04 13.6 1.9 4 7.1 0.1 2.9 2 1 1 3 3 3 0 Cupin Cupin_1 PF00190.22 RKO98696.1 - 0.086 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin PP2C PF00481.21 RKO98698.1 - 1.6e-23 83.6 0.0 2.2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RKO98698.1 - 0.01 15.5 0.1 0.012 15.2 0.1 1.3 1 1 0 1 1 1 0 Protein phosphatase 2C Cse1 PF08506.10 RKO98699.1 - 6.9e-110 367.3 0.0 1.3e-102 343.4 0.0 2.3 2 0 0 2 2 2 2 Cse1 CAS_CSE1 PF03378.15 RKO98699.1 - 3.2e-94 315.9 0.0 2.6e-93 312.9 0.0 2.2 2 1 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 RKO98699.1 - 2e-11 43.6 0.0 2.8e-10 39.9 0.0 3.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RKO98699.1 - 0.012 15.7 0.0 0.099 12.7 0.0 2.7 1 0 0 1 1 1 0 Exportin 1-like protein HEAT PF02985.22 RKO98699.1 - 0.069 13.4 0.5 8.9 6.9 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat DUF3730 PF12530.8 RKO98699.1 - 0.17 11.4 2.8 19 4.7 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3730) Peptidase_C54 PF03416.19 RKO98700.1 - 5.7e-38 130.9 0.0 6.1e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 RKO98700.1 - 0.01 15.3 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C78 Clathrin PF00637.20 RKO98701.1 - 1.9e-194 637.3 27.2 1.6e-32 112.4 0.2 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 RKO98701.1 - 1.3e-35 119.9 0.6 2.9e-05 24.2 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 RKO98701.1 - 4.2e-32 109.9 0.3 2.9e-29 100.8 0.1 3.6 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 RKO98701.1 - 8.7e-12 44.2 0.4 1.8e-11 43.2 0.4 1.6 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 RKO98701.1 - 6.9e-07 28.7 5.8 0.0022 17.1 0.3 4.6 5 0 0 5 5 5 2 Coatomer WD associated region TPR_2 PF07719.17 RKO98701.1 - 0.0027 17.7 8.0 2.3 8.6 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Vps39_1 PF10366.9 RKO98701.1 - 0.0032 17.7 0.8 0.98 9.7 0.0 4.6 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_8 PF13181.6 RKO98701.1 - 0.014 15.5 0.9 41 4.7 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98701.1 - 0.019 14.8 2.0 19 5.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RKO98701.1 - 0.025 15.1 0.4 27 5.4 0.0 5.2 5 1 1 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO98701.1 - 0.42 10.9 3.3 1.3 9.3 0.2 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 tRNA_anti-codon PF01336.25 RKO98702.1 - 0.085 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TP_methylase PF00590.20 RKO98703.1 - 4.6e-24 85.5 0.0 7.8e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NIF PF03031.18 RKO98705.1 - 3.4e-55 186.1 0.1 4.1e-55 185.8 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WzyE PF06899.11 RKO98705.1 - 0.23 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase Myb_DNA-binding PF00249.31 RKO98706.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Macoilin PF09726.9 RKO98706.1 - 6.6 5.2 10.6 15 4.0 10.6 1.6 1 0 0 1 1 1 0 Macoilin family Prefoldin PF02996.17 RKO98707.1 - 6e-30 103.6 1.6 8.2e-30 103.2 1.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit AAA_13 PF13166.6 RKO98707.1 - 0.00099 17.9 0.9 0.0012 17.6 0.9 1.0 1 0 0 1 1 1 1 AAA domain Prefoldin_2 PF01920.20 RKO98707.1 - 0.0015 18.5 3.4 0.045 13.7 0.2 2.2 2 0 0 2 2 2 2 Prefoldin subunit Phage_GP20 PF06810.11 RKO98707.1 - 0.003 17.4 3.5 0.44 10.4 0.1 2.1 2 0 0 2 2 2 2 Phage minor structural protein GP20 End3 PF12761.7 RKO98707.1 - 0.0067 16.6 1.6 0.02 15.1 0.2 2.0 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 L31 PF09784.9 RKO98707.1 - 0.011 16.1 0.7 0.47 10.9 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Noelin-1 PF12308.8 RKO98707.1 - 0.02 14.8 0.6 3.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein Syntaxin-6_N PF09177.11 RKO98707.1 - 0.028 15.0 4.5 0.35 11.4 1.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal LMP PF04778.12 RKO98707.1 - 0.056 13.4 0.8 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 LMP repeated region DUF5082 PF16888.5 RKO98707.1 - 0.078 13.3 1.6 4.5 7.6 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 RKO98707.1 - 1.5 9.3 4.9 21 5.6 0.4 2.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GATA PF00320.27 RKO98708.1 - 7.6e-14 51.0 3.5 1.3e-13 50.3 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger Elf1 PF05129.13 RKO98708.1 - 0.0059 16.6 0.2 0.0091 16.0 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PRCC PF10253.9 RKO98708.1 - 2.8 8.7 6.7 3.1 8.5 6.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ank_4 PF13637.6 RKO98709.1 - 1.1e-14 54.5 0.1 1.5e-07 31.8 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 RKO98709.1 - 3.9e-11 42.9 0.2 0.00092 19.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RKO98709.1 - 2.6e-10 40.8 0.0 1.9e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKO98709.1 - 3.1e-09 36.9 0.6 2.3e-05 24.5 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKO98709.1 - 4.2e-07 29.8 0.0 0.012 16.1 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeat DEAD PF00270.29 RKO98710.1 - 1.2e-39 135.9 0.0 3.6e-39 134.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98710.1 - 1e-26 93.4 0.0 2.6e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98710.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 RKO98710.1 - 0.16 12.1 2.2 0.32 11.1 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle PRA1 PF03208.19 RKO98711.1 - 6.5e-29 100.4 4.9 7.4e-29 100.2 4.9 1.0 1 0 0 1 1 1 1 PRA1 family protein HAT_KAT11 PF08214.11 RKO98712.1 - 1.3e-13 50.9 0.0 2.9e-13 49.8 0.0 1.3 1 1 0 1 1 1 1 Histone acetylation protein NCA2 PF08637.10 RKO98713.1 - 1.7e-72 244.0 0.0 3.5e-72 243.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FeS_assembly_P PF01883.19 RKO98713.1 - 0.097 12.9 0.7 9.2 6.5 0.0 3.1 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 RKO98714.1 - 1.1e-47 162.1 0.0 1.8e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 RKO98714.1 - 4.9e-33 113.5 0.5 8.5e-33 112.7 0.5 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 RKO98714.1 - 2e-14 53.4 0.0 4.7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKO98714.1 - 5.6e-06 26.7 1.4 6.6e-06 26.4 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RKO98714.1 - 0.00037 20.6 0.0 0.00089 19.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 RKO98714.1 - 0.0073 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 RKO98714.1 - 0.0073 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 RKO98714.1 - 0.018 14.9 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain CAP_N PF01213.19 RKO98715.1 - 0.23 10.9 6.0 0.29 10.6 6.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 RKO98715.1 - 0.37 10.8 2.8 0.42 10.7 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_M3 PF01432.20 RKO98716.1 - 4.2e-72 243.9 0.0 5.5e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Sdh_cyt PF01127.22 RKO98717.1 - 4.8e-21 75.0 4.6 5.2e-21 74.9 4.6 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Polysacc_deac_1 PF01522.21 RKO98718.1 - 1.5e-32 112.1 0.0 2.3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 RKO98718.1 - 0.00026 20.3 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 RKO98720.1 - 1.7e-33 115.2 0.0 2.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 RKO98720.1 - 0.00019 20.7 0.0 0.00024 20.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Chorismate_bind PF00425.18 RKO98721.1 - 2.2e-29 102.8 0.0 2.4e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 chorismate binding enzyme zf-C2H2 PF00096.26 RKO98722.1 - 6.8e-10 38.9 12.9 0.00042 20.6 1.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO98722.1 - 1.2e-09 38.2 11.9 0.0016 19.1 0.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO98722.1 - 0.00034 20.9 17.5 0.96 10.0 4.8 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RKO98722.1 - 0.0038 17.2 3.1 0.027 14.5 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKO98722.1 - 0.0085 15.8 0.9 0.12 12.1 0.5 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-DNA_Pol PF08996.10 RKO98722.1 - 0.021 14.6 1.1 0.028 14.2 1.1 1.3 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2HC_2 PF13913.6 RKO98722.1 - 0.051 13.5 2.6 0.076 12.9 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RKO98722.1 - 0.15 12.4 6.0 0.28 11.5 0.2 3.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RKO98722.1 - 0.22 11.3 0.4 0.22 11.3 0.4 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RKO98723.1 - 6.9e-12 45.1 6.5 3.1e-06 27.3 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO98723.1 - 9.1e-08 32.2 2.6 9.1e-08 32.2 2.6 2.9 2 1 1 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO98723.1 - 1.5e-06 28.5 5.4 0.0043 17.8 0.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RKO98723.1 - 0.0038 17.4 1.3 1.6 8.9 0.1 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_11 PF16622.5 RKO98723.1 - 0.0064 16.2 1.1 0.15 11.9 0.1 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type FOXP-CC PF16159.5 RKO98723.1 - 0.018 15.6 0.1 2.3 8.9 0.0 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 RKO98723.1 - 0.032 14.2 0.1 1.1 9.3 0.0 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger IBR PF01485.21 RKO98723.1 - 0.039 14.2 1.2 0.73 10.1 0.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain WD40 PF00400.32 RKO98724.1 - 0.026 15.4 18.7 0.85 10.6 0.2 7.2 7 1 0 7 7 7 0 WD domain, G-beta repeat MBOAT PF03062.19 RKO98725.1 - 4.1e-33 115.2 22.0 5e-33 114.9 22.0 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RKO98725.1 - 0.00035 20.8 4.7 0.0005 20.3 3.6 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family zf-C2H2_4 PF13894.6 RKO98726.1 - 3.9e-10 39.7 4.4 0.00011 22.7 1.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO98726.1 - 4e-10 39.6 6.0 4.2e-05 23.7 2.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RKO98726.1 - 2.3e-06 27.8 1.9 0.025 14.9 2.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKO98726.1 - 3.7e-06 26.8 3.9 0.0058 16.6 1.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO98726.1 - 4.3e-05 23.7 10.9 0.0025 18.1 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HE PF16278.5 RKO98726.1 - 0.0017 18.7 2.4 0.3 11.5 0.1 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 RKO98726.1 - 0.0047 17.3 3.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.12 RKO98726.1 - 0.0056 16.9 1.3 0.011 15.9 1.3 1.5 1 1 0 1 1 1 1 TFIIH C1-like domain zf-LYAR PF08790.11 RKO98726.1 - 0.046 13.6 0.8 0.79 9.7 0.3 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF1364 PF07102.12 RKO98726.1 - 0.087 12.7 4.6 1.7 8.6 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) Evr1_Alr PF04777.13 RKO98726.1 - 0.2 12.2 2.5 8.1 7.0 0.6 2.0 1 1 1 2 2 2 0 Erv1 / Alr family Zn-ribbon_8 PF09723.10 RKO98726.1 - 0.21 11.7 2.3 2.2 8.5 2.1 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 RKO98726.1 - 3.8 7.3 7.7 13 5.7 0.0 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Peptidase_M24 PF00557.24 RKO98727.1 - 2.3e-47 161.4 0.0 2.8e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 RKO98727.1 - 1.7e-14 53.8 8.5 3.7e-14 52.7 8.5 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 RKO98727.1 - 0.00017 21.6 7.6 0.00037 20.5 7.6 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 RKO98727.1 - 0.23 11.3 5.9 0.14 12.0 3.9 1.8 2 0 0 2 2 2 0 HIT zinc finger Pex2_Pex12 PF04757.14 RKO98728.1 - 1e-12 48.2 0.8 1e-06 28.5 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RKO98728.1 - 3.3e-09 36.5 10.3 5e-09 35.9 10.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO98728.1 - 1.6e-08 34.8 11.7 2.3e-08 34.2 11.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKO98728.1 - 5.3e-08 32.6 10.7 7.6e-08 32.1 10.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKO98728.1 - 6.7e-07 29.1 11.9 1e-06 28.5 11.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RKO98728.1 - 7.7e-07 29.2 10.2 1.3e-06 28.5 10.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RKO98728.1 - 9e-07 28.7 9.9 1.3e-06 28.2 9.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO98728.1 - 1.3e-06 28.3 3.9 1.3e-06 28.3 2.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RKO98728.1 - 3.8e-06 27.1 9.1 6.1e-06 26.4 9.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO98728.1 - 2.9e-05 23.9 9.1 4.7e-05 23.3 9.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RKO98728.1 - 0.043 13.9 6.0 0.069 13.2 6.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 RKO98728.1 - 0.094 12.9 6.7 0.16 12.1 6.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 RKO98728.1 - 0.3 11.0 6.4 0.55 10.1 6.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DiS_P_DiS PF06750.13 RKO98728.1 - 0.39 10.9 2.6 0.75 9.9 2.6 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-WRNIP1_ubi PF18279.1 RKO98728.1 - 2.3 9.1 4.7 2.2 9.1 0.4 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_4 PF14570.6 RKO98728.1 - 8.4 6.3 15.4 40 4.1 15.6 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain LON_substr_bdg PF02190.16 RKO98729.1 - 1.2e-33 116.7 0.0 2.6e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RKO98729.1 - 3.7e-22 79.2 0.0 7.7e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKO98729.1 - 1.5e-05 25.2 0.5 0.0025 18.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 RKO98729.1 - 3.4e-05 24.0 0.0 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKO98729.1 - 3.5e-05 23.8 0.0 7.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKO98729.1 - 4.2e-05 23.4 0.0 0.00023 21.0 0.0 2.1 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RKO98729.1 - 0.00014 22.3 0.3 0.00095 19.6 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 RKO98729.1 - 0.00034 19.7 0.0 0.00067 18.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.6 RKO98729.1 - 0.0052 17.3 0.1 0.014 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 RKO98729.1 - 0.011 16.1 0.0 0.035 14.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 RKO98729.1 - 0.019 15.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 RKO98729.1 - 0.036 14.2 0.4 0.088 12.9 0.1 1.8 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.15 RKO98729.1 - 0.041 13.8 0.2 0.57 10.1 0.1 2.5 1 1 1 2 2 2 0 NTPase IstB_IS21 PF01695.17 RKO98729.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 RKO98729.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain DnaB_2 PF07261.11 RKO98729.1 - 0.072 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Replication initiation and membrane attachment AAA_3 PF07726.11 RKO98729.1 - 0.08 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 RKO98729.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RKO98729.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 RKO98730.1 - 0.00047 20.0 0.1 0.0013 18.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RKO98730.1 - 0.0029 17.4 0.2 0.0069 16.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 RKO98731.1 - 3.2e-19 68.7 2.4 0.00019 21.7 0.4 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO98731.1 - 2.6e-11 43.1 5.9 0.00048 19.8 0.1 4.7 1 1 4 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 RKO98731.1 - 8.7e-06 25.4 2.1 13 6.1 0.0 7.0 9 0 0 9 9 9 1 Leucine Rich repeat LRR_9 PF14580.6 RKO98731.1 - 0.00026 20.5 1.7 0.18 11.3 0.0 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RKO98731.1 - 0.022 15.2 6.7 59 4.8 0.1 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat SEEEED PF14797.6 RKO98731.1 - 4.9 7.3 19.2 8.7 6.5 19.2 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex MCM_bind PF09739.9 RKO98731.1 - 6.4 5.1 5.7 7.4 4.9 4.8 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor FtsJ PF01728.19 RKO98732.1 - 1.7e-39 135.8 0.0 2e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 RKO98732.1 - 0.036 12.1 0.0 0.042 11.9 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase MFS_1 PF07690.16 RKO98734.1 - 9.7e-20 70.8 48.5 2.2e-17 63.0 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RKO98734.1 - 2.3e-05 23.4 11.8 4.4e-05 22.5 11.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MA3 PF02847.17 RKO98735.1 - 1.7e-15 57.0 0.0 4.1e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 MA3 domain MIF4G PF02854.19 RKO98735.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 MIF4G domain SDA1 PF05285.12 RKO98735.1 - 4.3 6.7 17.9 8 5.8 17.9 1.4 1 0 0 1 1 1 0 SDA1 Med21 PF11221.8 RKO98736.1 - 2.2e-13 50.7 0.0 3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex FAD_binding_3 PF01494.19 RKO98737.1 - 3.8e-09 36.2 0.4 0.00011 21.5 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain SH3_9 PF14604.6 RKO98738.1 - 0.0005 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO98738.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DSS1_SEM1 PF05160.13 RKO98739.1 - 4.3e-13 49.1 0.1 6.6e-08 32.5 0.0 2.1 2 0 0 2 2 2 2 DSS1/SEM1 family AAA PF00004.29 RKO98740.1 - 2.3e-40 138.1 0.0 3.4e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO98740.1 - 2.3e-08 33.7 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RKO98740.1 - 1.2e-07 32.0 0.4 0.0024 18.1 0.0 2.5 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 RKO98740.1 - 2.9e-06 27.8 1.1 0.0029 18.0 0.0 2.8 2 2 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 RKO98740.1 - 6.4e-06 26.2 0.1 2.8e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKO98740.1 - 1.3e-05 25.0 0.0 2.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RKO98740.1 - 2.9e-05 23.9 0.0 4.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 RKO98740.1 - 0.00018 21.1 0.0 0.0052 16.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 RKO98740.1 - 0.00039 20.6 0.0 0.00075 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 RKO98740.1 - 0.00054 19.4 0.1 0.83 9.0 0.0 2.6 1 1 2 3 3 3 2 Bacterial TniB protein Mg_chelatase PF01078.21 RKO98740.1 - 0.0011 18.4 0.2 0.0022 17.4 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 RKO98740.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 RKO98740.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RKO98740.1 - 0.0015 17.8 0.2 0.0035 16.6 0.1 1.5 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 RKO98740.1 - 0.0019 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO98740.1 - 0.002 18.7 0.0 0.0033 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 RKO98740.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DUF815 PF05673.13 RKO98740.1 - 0.0036 16.5 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 RKO98740.1 - 0.0042 16.6 0.2 0.016 14.8 0.2 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 RKO98740.1 - 0.013 14.9 0.2 0.14 11.4 0.0 2.1 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 RKO98740.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 RKO98740.1 - 0.029 14.1 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 RKO98740.1 - 0.033 14.4 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKO98740.1 - 0.055 13.2 0.3 0.12 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKO98740.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 RNA helicase TsaE PF02367.17 RKO98740.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 RKO98740.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RKO98740.1 - 0.063 13.2 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 RKO98740.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 RKO98740.1 - 0.075 13.4 0.2 0.37 11.1 0.2 2.1 2 1 1 3 3 3 0 AAA domain Hydin_ADK PF17213.3 RKO98740.1 - 0.1 12.9 0.4 1.4 9.1 0.0 2.4 1 1 0 2 2 2 0 Hydin Adenylate kinase-like domain ATPase_2 PF01637.18 RKO98740.1 - 0.13 12.2 0.0 6.2 6.7 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea IPT PF01745.16 RKO98740.1 - 0.15 11.4 0.2 0.94 8.8 0.1 2.2 1 1 2 3 3 3 0 Isopentenyl transferase Guanylate_kin PF00625.21 RKO98740.1 - 0.16 11.7 0.0 1.6 8.3 0.0 2.3 1 1 0 2 2 2 0 Guanylate kinase Cytidylate_kin PF02224.18 RKO98740.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase IGR PF09597.10 RKO98742.1 - 1.6e-19 69.7 0.7 1.2e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 IGR protein motif COX6B PF02297.17 RKO98743.1 - 1.8e-18 66.5 8.5 2.1e-18 66.3 8.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 RKO98743.1 - 0.0043 17.0 3.7 0.0073 16.3 3.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 RKO98743.1 - 0.015 15.2 0.4 0.026 14.5 0.4 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ProRS-C_1 PF09180.11 RKO98744.1 - 1e-21 76.9 0.5 2.2e-21 75.8 0.5 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 RKO98744.1 - 2.9e-20 73.0 0.0 7.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RKO98744.1 - 4.8e-15 55.5 0.0 9.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain FH2 PF02181.23 RKO98745.1 - 1.2e-39 136.6 0.0 1.3e-39 136.4 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain MMS1_N PF10433.9 RKO98746.1 - 4.4e-124 414.8 0.0 2.7e-123 412.2 0.0 2.4 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RKO98746.1 - 3.2e-73 246.9 0.0 1.6e-71 241.3 0.0 2.8 3 1 0 3 3 3 1 CPSF A subunit region Mon1 PF03164.14 RKO98747.1 - 1.5e-35 123.0 0.0 2.1e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 SR-25 PF10500.9 RKO98747.1 - 1.1 8.8 3.5 1.7 8.2 3.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1656 PF07869.12 RKO98747.1 - 4.8 7.3 5.8 19 5.3 5.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Cyclin PF08613.11 RKO98749.1 - 5.2e-15 56.2 0.0 5.2e-15 56.2 0.0 2.1 2 2 0 2 2 2 1 Cyclin Presenilin PF01080.17 RKO98749.1 - 0.23 10.2 1.5 0.39 9.4 1.5 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.18 RKO98749.1 - 0.28 10.7 8.8 0.19 11.3 3.1 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) SUIM_assoc PF16619.5 RKO98749.1 - 0.87 9.7 9.7 2.6 8.2 6.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PepSY_TM PF03929.16 RKO98749.1 - 3.1 7.4 9.4 0.49 10.0 2.7 2.1 2 0 0 2 2 2 0 PepSY-associated TM region Med3 PF11593.8 RKO98749.1 - 8.2 5.5 37.3 0.41 9.8 20.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 RKO98750.1 - 4.1e-11 42.8 0.0 4.7e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98750.1 - 1.3e-07 31.2 0.0 1.5e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase GDP_Man_Dehyd PF16363.5 RKO98751.1 - 2.1e-51 175.3 0.0 3.4e-51 174.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RKO98751.1 - 6.3e-51 173.2 0.0 8.1e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RKO98751.1 - 1e-16 60.9 0.0 8.2e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RKO98751.1 - 6.9e-16 58.1 0.0 6.8e-15 54.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RKO98751.1 - 9.7e-14 51.1 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RKO98751.1 - 1.1e-07 31.3 0.0 7e-05 22.1 0.0 2.4 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 RKO98751.1 - 3.3e-07 30.4 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RKO98751.1 - 1.4e-05 25.1 0.2 6.5e-05 22.9 0.2 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 RKO98751.1 - 4e-05 23.3 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 RKO98751.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 RKO98751.1 - 0.012 15.8 0.1 0.03 14.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 RKO98751.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_17 PF12692.7 RKO98751.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase LPMO_10 PF03067.15 RKO98753.1 - 3.2e-08 34.5 8.4 3.8e-08 34.2 0.5 3.4 2 2 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading MBOAT PF03062.19 RKO98755.1 - 1.2e-40 139.9 21.9 1.2e-40 139.9 21.9 1.8 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pro_isomerase PF00160.21 RKO98756.1 - 7.4e-40 136.8 0.0 8.3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD THUMP PF02926.17 RKO98757.1 - 7.9e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 THUMP domain COG4 PF08318.12 RKO98758.1 - 2.4e-39 135.3 0.0 3.5e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein MCD_N PF17408.2 RKO98758.1 - 0.053 13.7 0.1 0.57 10.3 0.1 2.9 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain CysG_dimeriser PF10414.9 RKO98758.1 - 0.97 9.2 18.5 0.33 10.7 1.3 5.9 5 0 0 5 5 5 0 Sirohaem synthase dimerisation region Arm-DNA-bind_3 PF13356.6 RKO98758.1 - 1.2 9.6 7.2 1.7 9.1 0.0 4.2 3 0 0 3 3 3 0 Arm DNA-binding domain FA_desaturase PF00487.24 RKO98759.1 - 5.9e-27 95.1 29.4 5.9e-27 95.1 29.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 RKO98759.1 - 9.7e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arteri_Gl PF00951.18 RKO98759.1 - 2.3 8.0 5.4 0.28 11.0 0.2 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Bd3614-deam PF14439.6 RKO98760.1 - 0.77 9.8 9.5 0.071 13.2 4.9 1.6 2 0 0 2 2 2 0 Bd3614-like deaminase HMGL-like PF00682.19 RKO98761.1 - 4.8e-79 265.6 0.1 7.8e-79 264.9 0.1 1.3 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 RKO98761.1 - 0.091 13.3 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Ribosomal_L37 PF08561.10 RKO98762.1 - 0.074 13.6 2.2 0.25 11.9 2.2 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Serglycin PF04360.12 RKO98762.1 - 0.13 12.2 0.3 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Serglycin Sec16_N PF12935.7 RKO98762.1 - 7.2 6.7 8.6 0.41 10.8 3.1 1.7 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus Peptidase_S9 PF00326.21 RKO98763.1 - 5.7e-22 78.2 0.3 1.3e-12 47.7 0.0 3.5 3 1 1 4 4 4 3 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 RKO98763.1 - 2.6e-05 23.2 0.0 5e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Thyroglob_assoc PF16597.5 RKO98763.1 - 0.077 13.3 0.3 0.3 11.4 0.3 2.0 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain DEAD PF00270.29 RKO98765.1 - 6.4e-46 156.3 0.5 6.4e-46 156.3 0.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98765.1 - 3.7e-32 111.0 2.3 6.7e-31 106.9 0.2 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98765.1 - 7.1e-09 35.9 0.2 1.6e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKO98765.1 - 1.1e-05 25.9 0.1 0.0047 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RKO98765.1 - 0.0012 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RKO98765.1 - 0.0053 16.7 0.2 0.031 14.3 0.1 2.3 1 1 1 2 2 2 1 Flavivirus DEAD domain CMS1 PF14617.6 RKO98765.1 - 0.0062 15.9 0.3 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 RKO98765.1 - 0.01 16.1 0.5 0.048 13.9 0.2 2.3 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 RKO98765.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Helicase Phage_integrase PF00589.22 RKO98765.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family TFIIE_alpha PF02002.17 RKO98766.1 - 6.7e-05 22.7 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_9 PF08221.11 RKO98766.1 - 0.00012 22.1 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 RKO98766.1 - 0.0043 16.8 0.0 0.027 14.2 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 TrmB PF01978.19 RKO98766.1 - 0.0054 16.6 0.1 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB SNARE PF05739.19 RKO98767.1 - 3.1e-16 59.1 3.8 4.4e-16 58.6 0.1 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 RKO98767.1 - 1.5e-06 28.0 0.2 2.6e-06 27.2 0.2 1.3 1 0 0 1 1 1 1 Syntaxin PIRT PF15099.6 RKO98767.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Tweety PF04906.13 RKO98767.1 - 0.0021 16.8 2.2 0.0042 15.8 0.9 2.0 2 1 1 3 3 3 1 Tweety Prominin PF05478.11 RKO98767.1 - 0.0049 14.9 0.7 0.0085 14.1 0.5 1.4 2 0 0 2 2 2 1 Prominin BLOC1_2 PF10046.9 RKO98767.1 - 0.059 13.7 0.9 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TraC PF07820.12 RKO98767.1 - 0.086 13.2 2.2 0.31 11.4 0.6 2.7 2 1 1 3 3 3 0 TraC-like protein DUF2019 PF09450.10 RKO98767.1 - 0.092 12.7 0.5 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Synaptobrevin PF00957.21 RKO98767.1 - 8.5 6.3 6.9 2.1 8.2 2.8 2.2 2 1 0 2 2 2 0 Synaptobrevin NAC PF01849.18 RKO98768.1 - 1.6e-11 44.0 0.1 2.5e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.31 RKO98768.1 - 0.035 14.0 0.2 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 UBA/TS-N domain HOIP-UBA PF16678.5 RKO98768.1 - 0.11 12.5 0.1 0.73 9.8 0.1 2.1 1 1 0 1 1 1 0 HOIP UBA domain pair zf-RING_UBOX PF13445.6 RKO98769.1 - 1.6e-07 31.2 2.3 1.6e-07 31.2 2.3 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RKO98769.1 - 9.9e-07 28.5 3.3 1.6e-06 27.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO98769.1 - 2.4e-06 27.8 4.9 2.8e-06 27.6 4.1 1.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKO98769.1 - 1.1e-05 25.1 5.3 2.1e-05 24.3 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TackOD1 PF18551.1 RKO98769.1 - 0.00031 20.5 0.7 0.00049 19.8 0.7 1.2 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zf-RING_5 PF14634.6 RKO98769.1 - 0.0029 17.5 5.0 0.0068 16.3 5.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RKO98769.1 - 0.0044 16.8 9.6 0.13 12.1 9.1 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RKO98769.1 - 0.011 15.9 9.7 0.079 13.1 9.8 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 RKO98769.1 - 0.017 15.0 9.0 0.38 10.7 9.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKO98769.1 - 0.037 13.8 0.7 0.072 12.9 0.7 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 RKO98769.1 - 0.063 13.1 7.8 0.097 12.5 7.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_4 PF07975.12 RKO98769.1 - 0.16 12.3 4.6 0.33 11.2 4.6 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 RKO98769.1 - 0.85 9.8 7.4 24 5.2 4.7 2.7 2 1 0 2 2 2 0 Zinc ribbon domain Prok-RING_1 PF14446.6 RKO98769.1 - 1.3 9.0 6.3 11 6.1 1.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_6 PF14835.6 RKO98769.1 - 1.5 8.7 9.0 14 5.6 9.0 2.4 1 1 1 2 2 2 0 zf-RING of BARD1-type protein IBR PF01485.21 RKO98769.1 - 2.9 8.2 6.5 1 9.7 0.8 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 RKO98770.1 - 3.1e-73 246.4 0.0 3.7e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98770.1 - 1.1e-39 136.3 0.0 1.4e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO98770.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RKO98770.1 - 9.7e-05 22.0 0.4 0.00015 21.5 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RKO98770.1 - 0.00062 19.2 0.1 0.0013 18.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO98770.1 - 0.0007 19.6 2.5 0.0017 18.3 0.9 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKO98770.1 - 0.0016 17.4 0.2 0.0024 16.9 0.2 1.3 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 RKO98770.1 - 0.05 12.4 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 RKO98770.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAP PF07174.11 RKO98770.1 - 7.9 5.8 17.4 10 5.5 17.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Bromodomain PF00439.25 RKO98772.1 - 1.8e-16 60.0 0.1 3.5e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 RKO98772.1 - 7.2e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RKO98772.1 - 1.8e-06 27.9 0.1 3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKO98772.1 - 0.00016 22.1 0.1 0.00027 21.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ytp1 PF10355.9 RKO98772.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) Complex1_LYR_2 PF13233.6 RKO98773.1 - 1.1e-12 48.5 0.7 1.3e-12 48.3 0.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RKO98773.1 - 1.1e-08 35.0 0.2 2e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Fes1 PF08609.10 RKO98775.1 - 4e-21 75.7 3.3 1.1e-19 71.0 3.3 2.6 1 1 0 1 1 1 1 Nucleotide exchange factor Fes1 Arm_2 PF04826.13 RKO98775.1 - 0.00044 19.8 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 RKO98775.1 - 0.00098 19.1 0.1 1.7 8.8 0.1 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 RKO98775.1 - 0.0033 17.4 0.2 0.0076 16.2 0.2 1.6 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3361 PF11841.8 RKO98775.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) DUF4704 PF15787.5 RKO98775.1 - 0.053 12.8 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) MMS1_N PF10433.9 RKO98776.1 - 5.5e-60 203.4 0.0 1.3e-59 202.2 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RKO98776.1 - 1.4e-36 126.5 0.0 2.4e-27 96.1 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region NOA36 PF06524.12 RKO98776.1 - 6.6 5.9 4.7 14 4.9 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein Kin17_mid PF10357.9 RKO98778.1 - 2.5e-37 127.6 0.0 3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 RKO98778.1 - 0.00051 20.2 0.4 0.00086 19.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKO98778.1 - 0.0087 16.4 1.3 0.017 15.5 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RKO98778.1 - 0.13 12.6 0.1 0.48 10.8 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pex24p PF06398.11 RKO98779.1 - 0.00013 21.1 0.4 0.00016 20.8 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin LCE PF14672.6 RKO98779.1 - 0.02 15.5 0.2 0.05 14.2 0.2 1.7 1 0 0 1 1 1 0 Late cornified envelope WD40 PF00400.32 RKO98780.1 - 2.2e-43 145.4 14.9 3.4e-08 34.0 0.1 7.2 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98780.1 - 9.4e-11 41.9 0.1 0.0022 18.3 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO98780.1 - 2.1e-06 26.7 3.6 0.098 11.3 0.1 4.3 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO98780.1 - 0.00047 19.2 3.3 0.25 10.3 0.1 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 RKO98780.1 - 0.0043 17.0 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.16 RKO98780.1 - 0.053 12.0 0.2 0.22 10.0 0.1 2.0 2 1 1 3 3 3 0 Cytochrome D1 heme domain LisH_TPL PF17814.1 RKO98780.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 LisH-like dimerisation domain PALB2_WD40 PF16756.5 RKO98780.1 - 0.35 9.7 2.3 5.4 5.8 0.1 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Peptidase_M41 PF01434.18 RKO98781.1 - 9.6e-62 208.2 0.2 2e-61 207.2 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 RKO98781.1 - 1.7e-44 151.4 0.0 4.9e-44 150.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO98781.1 - 8.4e-10 38.3 0.0 2.7e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RKO98781.1 - 2.2e-05 24.9 5.1 0.002 18.5 0.1 3.8 3 2 0 4 4 4 1 AAA ATPase domain TIP49 PF06068.13 RKO98781.1 - 2.5e-05 23.7 0.0 4.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 RKO98781.1 - 5e-05 23.1 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RKO98781.1 - 0.00028 20.6 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 RKO98781.1 - 0.00029 20.9 0.0 0.0019 18.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO98781.1 - 0.0011 19.3 0.1 0.015 15.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 RKO98781.1 - 0.0014 17.9 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RKO98781.1 - 0.0022 18.5 0.0 0.0079 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain Peptidase_M50B PF13398.6 RKO98781.1 - 0.0024 17.5 0.6 0.087 12.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase M50B-like AAA_33 PF13671.6 RKO98781.1 - 0.0037 17.4 0.1 0.03 14.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 RKO98781.1 - 0.0066 16.2 0.1 0.024 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 RKO98781.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RKO98781.1 - 0.041 13.2 0.6 0.29 10.4 0.2 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_25 PF13481.6 RKO98781.1 - 0.045 13.3 0.2 0.29 10.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 RKO98781.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 RKO98781.1 - 0.046 13.1 0.2 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 RKO98781.1 - 0.047 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RKO98781.1 - 0.059 13.6 2.0 0.071 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 RKO98781.1 - 0.13 12.1 0.0 0.38 10.5 0.0 1.8 2 1 0 2 2 2 0 Bacterial dnaA protein ATPase_2 PF01637.18 RKO98781.1 - 0.13 12.2 0.0 6.8 6.5 0.0 2.3 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 RKO98781.1 - 0.14 11.7 0.0 0.99 8.9 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RKO98781.1 - 0.18 11.7 1.6 1 9.2 0.1 2.6 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 RKO98781.1 - 0.18 12.2 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSM PF04612.12 RKO98782.1 - 2.1 8.4 4.4 0.71 9.9 0.6 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TFIIF_alpha PF05793.12 RKO98782.1 - 5.3 5.5 5.2 7.4 5.0 5.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PWI PF01480.17 RKO98783.1 - 1.2e-14 54.4 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 PWI domain ADK PF00406.22 RKO98784.1 - 2.5e-59 199.7 0.0 2.9e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RKO98784.1 - 5.5e-21 75.4 0.2 1.8e-20 73.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 RKO98784.1 - 1.6e-16 59.9 0.0 4.3e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 RKO98784.1 - 0.00027 21.1 0.0 0.00053 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO98784.1 - 0.0069 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RKO98784.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DER1 PF04511.15 RKO98785.1 - 1.1e-55 188.6 2.4 1.2e-55 188.4 2.4 1.0 1 0 0 1 1 1 1 Der1-like family E1-E2_ATPase PF00122.20 RKO98786.1 - 4.8e-43 146.8 1.6 2.4e-42 144.5 0.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RKO98786.1 - 8.7e-21 74.4 11.2 2.8e-15 56.5 0.7 3.2 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RKO98786.1 - 3.9e-20 71.7 0.0 8.2e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RKO98786.1 - 1.3e-18 68.1 0.0 1.3e-16 61.6 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKO98786.1 - 6e-09 35.5 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKO98786.1 - 0.00036 20.4 0.5 0.043 13.5 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pox_A14 PF05767.12 RKO98786.1 - 0.037 14.2 1.4 0.083 13.1 0.1 2.3 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 HIG_1_N PF04588.13 RKO98786.1 - 0.55 10.5 4.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Hypoxia induced protein conserved region DUF4838 PF16126.5 RKO98788.1 - 0.067 12.5 0.1 0.075 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Cytochrom_B561 PF03188.16 RKO98789.1 - 8.6e-08 32.4 4.5 2.4e-07 31.0 4.4 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF1427 PF07235.11 RKO98789.1 - 0.61 10.1 2.7 2.1 8.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF3619 PF12279.8 RKO98789.1 - 1.7 9.0 5.4 0.57 10.5 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) DUF726 PF05277.12 RKO98790.1 - 2.5e-77 260.1 0.0 3.1e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3089 PF11288.8 RKO98790.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 RKO98790.1 - 0.12 13.0 0.7 0.55 10.8 0.7 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF726 PF05277.12 RKO98791.1 - 9.2e-21 74.1 13.0 1.2e-20 73.8 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Ran-binding PF05508.11 RKO98792.1 - 1.4e-47 162.2 0.0 1.8e-46 158.6 0.0 2.0 2 0 0 2 2 2 2 RanGTP-binding protein Ku PF02735.16 RKO98793.1 - 1.3e-14 54.4 0.0 5.8e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 RKO98793.1 - 0.00027 20.8 0.0 0.00085 19.1 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 RKO98793.1 - 0.1 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Profilin PF00235.19 RKO98795.1 - 2.6e-46 157.0 0.1 2.9e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 Profilin Solute_trans_a PF03619.16 RKO98796.1 - 9.5e-64 215.5 16.8 1.1e-63 215.3 16.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Thioredoxin PF00085.20 RKO98798.1 - 9e-07 28.8 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin HAD_2 PF13419.6 RKO98802.1 - 1.9e-18 67.2 0.0 1.7e-17 64.1 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKO98802.1 - 5.4e-10 39.9 0.0 1.6e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RKO98802.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RKO98802.1 - 0.00061 19.9 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 RKO98802.1 - 0.018 15.4 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5016 PF16408.5 RKO98802.1 - 0.098 12.7 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5016) NUC173 PF08161.12 RKO98803.1 - 2.4e-27 95.9 0.1 2.2e-26 92.8 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.22 RKO98803.1 - 0.013 15.7 2.5 1.4 9.4 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat TAN PF11640.8 RKO98803.1 - 0.023 14.8 0.2 0.17 12.0 0.0 2.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Ribosomal_S10 PF00338.22 RKO98804.1 - 1.7e-17 63.4 0.0 1.9e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribonuclease_T2 PF00445.18 RKO98805.1 - 5.7e-17 62.5 0.0 6.2e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4349 PF14257.6 RKO98805.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) WD40 PF00400.32 RKO98806.1 - 1.3e-08 35.3 5.0 0.00013 22.6 0.0 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat LisH PF08513.11 RKO98806.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 LisH zf-Tim10_DDP PF02953.15 RKO98807.1 - 1.8e-18 65.9 0.2 2e-18 65.8 0.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mtd_N PF18454.1 RKO98808.1 - 0.00062 19.7 0.1 1.8 8.7 0.1 2.8 2 0 0 2 2 2 2 Major tropism determinant N-terminal domain Cys_Met_Meta_PP PF01053.20 RKO98809.1 - 5.3e-102 341.2 0.0 1.6e-85 287.0 0.0 4.4 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 RKO98810.1 - 1.3e-63 214.8 0.0 1.5e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98810.1 - 3.9e-27 95.2 0.0 5.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKO98810.1 - 0.00074 19.5 0.7 0.002 18.1 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKO98810.1 - 0.0043 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO98810.1 - 0.028 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 RKO98810.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 RKO98810.1 - 0.3 10.0 0.0 1.7 7.5 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RKO98810.1 - 0.3 10.4 1.2 1.5 8.1 1.2 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cytidylate_kin PF02224.18 RKO98811.1 - 2e-07 31.0 0.0 0.00021 21.1 0.0 2.1 2 0 0 2 2 2 2 Cytidylate kinase AAA_33 PF13671.6 RKO98811.1 - 7.4e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO98811.1 - 5.5e-06 27.0 0.0 5.1e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO98811.1 - 0.002 18.4 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKO98811.1 - 0.0054 17.0 0.7 0.15 12.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 RKO98811.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 RKO98811.1 - 0.011 16.1 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 RKO98811.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 RKO98811.1 - 0.067 13.3 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase AAA_16 PF13191.6 RKO98811.1 - 0.071 13.5 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 RKO98811.1 - 0.23 11.2 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 RKO98811.1 - 0.23 12.0 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Med3 PF11593.8 RKO98813.1 - 4.2 6.5 25.3 0.2 10.8 1.6 3.8 4 0 0 4 4 4 0 Mediator complex subunit 3 fungal ETC_C1_NDUFA5 PF04716.14 RKO98814.1 - 1.9e-18 66.0 0.1 3.1e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region COG7 PF10191.9 RKO98814.1 - 0.027 12.7 0.2 0.041 12.1 0.2 1.3 1 1 0 1 1 1 0 Golgi complex component 7 (COG7) Vps54_N PF10475.9 RKO98814.1 - 0.032 13.5 0.1 0.04 13.2 0.1 1.0 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex ATP-grasp_2 PF08442.10 RKO98815.1 - 5.7e-70 235.0 2.2 8.5e-70 234.4 0.7 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 RKO98815.1 - 2e-23 82.9 0.7 4e-23 81.9 0.7 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 RKO98815.1 - 8.2e-06 25.4 1.3 5.5e-05 22.7 0.3 2.3 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 RKO98815.1 - 0.021 14.6 0.2 0.2 11.4 0.0 2.2 1 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Myosin_head PF00063.21 RKO98816.1 - 2.5e-258 858.8 0.1 3.7e-258 858.3 0.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 RKO98816.1 - 6.2e-29 100.3 1.0 6.2e-29 100.3 1.0 2.7 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 RKO98816.1 - 1.5e-10 39.9 50.3 0.00035 20.1 1.7 7.4 7 0 0 7 7 7 4 IQ calmodulin-binding motif DUF812 PF05667.11 RKO98816.1 - 0.00031 19.8 16.4 0.00061 18.8 16.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Myosin_N PF02736.19 RKO98816.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 RKO98816.1 - 0.028 14.7 0.0 0.16 12.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.9 RKO98816.1 - 0.074 12.0 9.9 0.2 10.6 9.9 1.7 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Leu_zip PF15294.6 RKO98816.1 - 0.12 11.9 21.0 0.047 13.2 6.7 2.5 1 1 1 2 2 2 0 Leucine zipper SHE3 PF17078.5 RKO98816.1 - 0.13 12.0 12.5 0.94 9.2 11.1 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 RKO98816.1 - 0.17 12.3 21.7 0.98 9.9 4.9 3.7 2 1 0 2 2 2 0 Cell division protein ZapB FliD_N PF02465.18 RKO98816.1 - 0.65 10.7 12.1 5.4 7.8 1.9 3.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TolA_bind_tri PF16331.5 RKO98816.1 - 1.8 8.7 17.0 0.63 10.1 4.6 4.0 2 1 1 3 3 3 0 TolA binding protein trimerisation FapA PF03961.13 RKO98816.1 - 1.8 7.1 9.7 3.1 6.3 9.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A LPP PF04728.13 RKO98816.1 - 3.7 8.0 12.0 5.2 7.5 0.6 4.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 RKO98816.1 - 3.9 7.7 14.3 0.3 11.2 7.9 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 RKO98816.1 - 4.5 7.4 25.1 0.99 9.5 4.8 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 RKO98816.1 - 4.7 7.2 18.2 20 5.2 18.2 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 RKO98816.1 - 5.1 7.2 24.5 5.2 7.2 22.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.26 RKO98817.1 - 1.8e-16 59.6 10.5 0.0001 22.6 0.3 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO98817.1 - 1.6e-12 47.1 9.9 0.043 14.7 0.2 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO98817.1 - 1.5e-05 25.2 1.4 0.0011 19.3 0.1 4.8 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_aberr PF17017.5 RKO98817.1 - 0.00027 21.1 3.6 0.15 12.2 0.3 2.6 2 1 0 2 2 2 2 Aberrant zinc-finger Ogr_Delta PF04606.12 RKO98817.1 - 0.00029 20.7 5.7 0.33 11.0 0.6 3.2 1 1 2 3 3 3 2 Ogr/Delta-like zinc finger zf-C2H2_8 PF15909.5 RKO98817.1 - 0.00051 20.3 2.9 0.031 14.6 0.8 2.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 RKO98817.1 - 0.0062 16.3 4.6 0.73 9.6 0.4 3.3 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RKO98817.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 RKO98817.1 - 0.17 12.5 5.4 22 5.8 0.2 3.7 1 1 3 4 4 4 0 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 RKO98817.1 - 0.18 12.3 2.6 7.7 7.1 0.3 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 RKO98817.1 - 0.72 9.7 2.8 15 5.5 0.2 2.9 2 2 1 3 3 3 0 C2H2 type zinc-finger (1 copy) CHORD PF04968.12 RKO98817.1 - 2.5 8.9 7.1 15 6.4 0.8 3.4 2 2 1 3 3 3 0 CHORD zf-H2C2_5 PF13909.6 RKO98817.1 - 5.5 6.9 10.3 3.3 7.5 0.4 3.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain TRAPPC9-Trs120 PF08626.11 RKO98818.1 - 2.7e-74 250.4 0.0 2.2e-24 85.0 0.0 5.2 5 0 0 5 5 5 5 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 RKO98818.1 - 0.011 16.0 0.3 0.035 14.4 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PGM_PMM_IV PF00408.20 RKO98819.1 - 5.8e-13 48.8 1.0 8.3e-12 45.1 0.1 2.8 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 RKO98819.1 - 1.6e-11 44.0 0.2 4.5e-05 23.2 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RKO98819.1 - 0.0072 16.5 0.0 0.033 14.4 0.0 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RKO98819.1 - 0.013 16.1 0.2 0.15 12.7 0.2 2.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HEAT PF02985.22 RKO98820.1 - 0.033 14.4 0.5 0.3 11.4 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat Sel1 PF08238.12 RKO98821.1 - 5.5e-33 112.7 32.1 1.3e-07 32.1 0.1 7.3 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.6 RKO98821.1 - 1.1 10.1 26.7 0.78 10.5 0.6 6.9 7 2 0 7 7 7 0 Tetratricopeptide repeat ECSCR PF15820.5 RKO98822.1 - 0.19 11.6 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Shisa PF13908.6 RKO98822.1 - 1.5 9.1 8.2 0.1 12.8 0.5 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Rad60-SLD_2 PF13881.6 RKO98824.1 - 3.1e-14 53.0 0.0 4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RKO98824.1 - 0.026 14.2 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin family EGF_3 PF12947.7 RKO98825.1 - 0.0027 17.9 2.3 0.0056 16.8 2.3 1.6 1 0 0 1 1 1 1 EGF domain EGF PF00008.27 RKO98825.1 - 0.0065 16.7 4.3 0.021 15.1 4.3 1.8 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.15 RKO98825.1 - 0.022 14.9 1.7 0.022 14.9 1.7 1.9 2 1 0 2 2 2 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 RKO98825.1 - 0.17 12.2 11.4 0.089 13.1 3.8 2.4 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site IPK PF03770.16 RKO98826.1 - 1.4e-43 149.1 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase SPC12 PF06645.13 RKO98827.1 - 5.8e-23 80.8 1.0 8.3e-23 80.3 1.0 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) AMP-binding PF00501.28 RKO98828.1 - 2.1e-77 260.5 0.0 2.6e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO98828.1 - 4.8e-21 75.5 0.5 1.1e-20 74.3 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 RKO98828.1 - 7e-20 70.7 0.3 1.6e-19 69.5 0.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Sec1 PF00995.23 RKO98829.1 - 2e-107 360.9 0.0 2.2e-107 360.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sel1 PF08238.12 RKO98830.1 - 1.1e-34 118.0 30.7 2.8e-09 37.3 0.2 7.5 8 0 0 8 8 8 6 Sel1 repeat TPR_17 PF13431.6 RKO98830.1 - 2.5 8.7 4.8 47 4.7 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat SpoIIP PF07454.11 RKO98831.1 - 4.6e-05 23.0 3.8 4.6e-05 23.0 3.8 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF2076 PF09849.9 RKO98831.1 - 0.00021 21.4 18.6 0.00021 21.4 18.6 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DDHD PF02862.17 RKO98831.1 - 0.00049 20.3 3.5 0.00049 20.3 3.5 1.1 1 0 0 1 1 1 1 DDHD domain Pex14_N PF04695.13 RKO98831.1 - 0.0014 19.3 17.3 0.0015 19.2 17.3 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 RKO98831.1 - 0.0065 16.9 11.0 0.0076 16.7 11.0 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like PepSY_TM PF03929.16 RKO98831.1 - 0.047 13.4 4.4 0.049 13.3 4.4 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF4637 PF15470.6 RKO98831.1 - 0.065 13.0 6.7 0.083 12.6 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Plasmodium_Vir PF05795.11 RKO98831.1 - 0.12 11.7 3.4 0.12 11.7 3.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ABC2_membrane_2 PF12679.7 RKO98831.1 - 0.14 11.5 0.7 0.13 11.6 0.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_S49_N PF08496.10 RKO98831.1 - 0.2 11.7 9.3 0.25 11.4 9.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BORG_CEP PF14957.6 RKO98831.1 - 0.21 12.8 7.6 0.27 12.4 7.6 1.2 1 0 0 1 1 1 0 Cdc42 effector CTU2 PF10288.9 RKO98831.1 - 0.21 11.9 11.8 0.29 11.4 11.8 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Pal1 PF08316.11 RKO98831.1 - 0.27 12.0 5.7 0.31 11.8 5.7 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein PPL5 PF18168.1 RKO98831.1 - 0.31 10.3 9.0 0.37 10.0 9.0 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S15 PF02129.18 RKO98831.1 - 0.36 10.4 8.7 0.39 10.3 8.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Spt20 PF12090.8 RKO98831.1 - 0.39 10.3 46.9 0.52 9.9 46.9 1.2 1 0 0 1 1 1 0 Spt20 family Pannexin_like PF12534.8 RKO98831.1 - 0.39 9.7 7.9 0.41 9.7 7.9 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pox_L3_FP4 PF03339.14 RKO98831.1 - 0.41 9.6 3.2 0.51 9.3 3.2 1.1 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein TFIIA PF03153.13 RKO98831.1 - 0.45 10.5 39.8 0.52 10.3 39.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 RKO98831.1 - 0.59 9.6 9.8 0.66 9.5 9.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.14 RKO98831.1 - 0.59 10.1 19.0 0.89 9.5 19.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM91_C PF14648.6 RKO98831.1 - 0.65 8.8 5.7 0.69 8.7 5.7 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Peptidase_U57 PF05582.12 RKO98831.1 - 0.66 9.2 11.3 1 8.6 11.3 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF4228 PF14009.6 RKO98831.1 - 0.71 10.2 8.8 0.82 10.0 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Presenilin PF01080.17 RKO98831.1 - 0.73 8.5 19.8 0.88 8.3 19.8 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 RKO98831.1 - 1.1 8.0 11.7 1.2 7.9 11.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 eIF-3_zeta PF05091.12 RKO98831.1 - 1.2 8.0 25.4 1.3 7.9 25.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.9 RKO98831.1 - 1.3 9.1 13.6 1.6 8.8 13.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 RKO98831.1 - 1.3 8.0 14.3 1.4 7.8 14.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Otopetrin PF03189.13 RKO98831.1 - 1.4 7.7 7.1 1.6 7.5 7.1 1.1 1 0 0 1 1 1 0 Otopetrin PAT1 PF09770.9 RKO98831.1 - 1.4 7.1 27.3 1.6 6.9 27.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Eapp_C PF10238.9 RKO98831.1 - 1.6 8.8 16.7 2 8.4 16.7 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein NPR3 PF03666.13 RKO98831.1 - 1.7 7.4 14.9 1.9 7.2 14.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 RKO98831.1 - 2.1 7.6 24.6 2.7 7.3 24.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4407 PF14362.6 RKO98831.1 - 2.2 7.6 19.3 2.6 7.3 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2126 PF09899.9 RKO98831.1 - 2.3 6.2 10.9 2.7 6.0 10.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) HemX PF04375.14 RKO98831.1 - 2.3 7.4 27.5 2.5 7.3 27.5 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase RR_TM4-6 PF06459.12 RKO98831.1 - 2.4 7.9 16.3 2.9 7.6 16.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 RKO98831.1 - 2.5 7.8 14.9 3 7.5 14.9 1.1 1 0 0 1 1 1 0 Connexin FAM60A PF15396.6 RKO98831.1 - 2.5 8.1 12.0 2.9 7.8 12.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SpoVR PF04293.13 RKO98831.1 - 2.7 6.6 11.8 3 6.4 11.8 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF913 PF06025.12 RKO98831.1 - 2.7 6.9 9.6 3 6.7 9.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4770 PF15994.5 RKO98831.1 - 2.8 8.1 17.6 3.6 7.8 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Tim54 PF11711.8 RKO98831.1 - 3.2 6.4 15.3 4 6.1 15.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.11 RKO98831.1 - 3.3 6.1 12.2 3.6 6.0 12.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Rxt3 PF08642.10 RKO98831.1 - 4.3 8.1 8.2 6.3 7.6 8.2 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF719 PF05334.13 RKO98831.1 - 4.5 7.4 13.4 6.5 6.9 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) CLN3 PF02487.17 RKO98831.1 - 5 6.1 13.1 5.9 5.8 13.1 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4175 PF13779.6 RKO98831.1 - 5.3 4.8 37.9 5.7 4.7 37.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.13 RKO98831.1 - 5.5 6.7 15.6 6.7 6.4 15.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ALMT PF11744.8 RKO98831.1 - 5.6 5.7 13.1 6.7 5.4 13.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TERB2 PF15101.6 RKO98831.1 - 6.2 6.8 24.8 7.4 6.6 24.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ctr PF04145.15 RKO98831.1 - 6.2 7.4 11.8 7.6 7.1 11.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Het-C PF07217.11 RKO98831.1 - 6.5 5.2 9.8 7.4 5.0 9.8 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CDC45 PF02724.14 RKO98831.1 - 6.6 4.9 17.0 7.7 4.7 17.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.9 RKO98831.1 - 6.7 5.7 22.3 8.3 5.4 22.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CPSF100_C PF13299.6 RKO98831.1 - 7.2 6.8 14.5 9 6.5 14.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 RKO98831.1 - 7.5 5.7 7.5 8.4 5.5 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Agouti PF05039.12 RKO98831.1 - 7.7 7.3 14.6 11 6.8 14.6 1.2 1 0 0 1 1 1 0 Agouti protein Kei1 PF08552.11 RKO98831.1 - 7.9 6.3 10.1 9.3 6.1 10.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FAM176 PF14851.6 RKO98831.1 - 9 5.9 13.1 11 5.6 13.1 1.1 1 0 0 1 1 1 0 FAM176 family Membralin PF09746.9 RKO98831.1 - 9.3 5.2 9.1 11 5.0 9.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein CCDC53 PF10152.9 RKO98831.1 - 9.5 6.6 18.6 12 6.3 18.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex ATP_bind_1 PF03029.17 RKO98832.1 - 4.8e-86 288.5 0.1 5.5e-86 288.3 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 RKO98832.1 - 6e-05 22.9 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 RKO98832.1 - 7.7e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 RKO98832.1 - 0.00072 19.0 0.1 0.022 14.1 0.1 2.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF87 PF01935.17 RKO98832.1 - 0.0025 17.9 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 RKO98832.1 - 0.0043 16.7 0.1 0.035 13.7 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 RKO98832.1 - 0.0068 16.8 0.2 0.062 13.7 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NTPase_1 PF03266.15 RKO98832.1 - 0.007 16.3 0.1 2.8 7.8 0.0 2.4 3 0 0 3 3 2 1 NTPase AAA_18 PF13238.6 RKO98832.1 - 0.0075 16.8 0.0 0.023 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKO98832.1 - 0.0087 16.3 0.1 0.034 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RKO98832.1 - 0.01 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 RKO98832.1 - 0.01 15.7 0.3 0.84 9.5 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 RKO98832.1 - 0.013 15.0 0.6 4.6 6.7 0.1 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 RKO98832.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 RKO98832.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 RKO98832.1 - 0.015 14.4 0.0 0.048 12.7 0.0 1.8 3 0 0 3 3 3 0 Type II/IV secretion system protein PhoH PF02562.16 RKO98832.1 - 0.018 14.5 0.0 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein MMR_HSR1 PF01926.23 RKO98832.1 - 0.035 14.2 0.0 0.085 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 RKO98832.1 - 0.043 14.2 0.3 0.59 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RKO98832.1 - 0.048 13.6 0.4 0.13 12.2 0.4 1.8 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 RKO98832.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 RKO98832.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RKO98832.1 - 0.084 12.2 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 RKO98832.1 - 0.095 13.0 0.4 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RKO98832.1 - 0.11 11.7 1.3 0.4 9.8 0.1 2.3 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 RKO98832.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKO98832.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ADK PF00406.22 RKO98832.1 - 0.15 12.2 0.7 6 7.0 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase IBN_N PF03810.19 RKO98833.1 - 4e-14 52.3 0.0 9.8e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 RKO98833.1 - 0.00021 21.4 0.1 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 RKO98833.1 - 0.042 14.1 0.3 0.34 11.3 0.3 2.7 1 0 0 1 1 1 0 HEAT repeat Astro_capsid_p PF12226.8 RKO98833.1 - 1.2 8.2 4.5 1.9 7.5 4.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 RKO98833.1 - 1.2 9.6 9.3 4.9 7.6 9.3 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3138 PF11336.8 RKO98834.1 - 0.32 9.6 7.5 0.16 10.6 5.8 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) zf-C3HC4_3 PF13920.6 RKO98835.1 - 1.8e-06 27.7 0.4 2.9e-06 27.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO98835.1 - 8.5e-05 22.3 0.5 0.00016 21.5 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKO98835.1 - 0.0002 21.2 0.4 0.00038 20.3 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKO98835.1 - 0.00071 19.4 1.8 0.0012 18.6 1.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 RKO98835.1 - 0.0011 18.9 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 RKO98835.1 - 0.0025 18.1 0.4 0.0048 17.2 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RKO98835.1 - 0.0078 16.2 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain STT3 PF02516.14 RKO98836.1 - 3.7e-127 425.2 32.9 3.6e-126 422.0 32.9 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Cnd1 PF12717.7 RKO98837.1 - 1.4e-05 25.2 1.1 0.89 9.6 0.1 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RKO98837.1 - 3.7e-05 23.6 24.7 0.0076 16.4 0.1 6.6 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.7 RKO98837.1 - 0.021 15.1 0.2 2 8.8 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 RKO98837.1 - 0.089 12.5 2.5 0.53 10.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) CLASP_N PF12348.8 RKO98837.1 - 0.17 11.4 0.4 0.76 9.3 0.0 2.1 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 RKO98837.1 - 0.69 10.5 26.8 0.67 10.5 1.4 7.1 6 1 0 6 6 6 0 HEAT-like repeat Cwf_Cwc_15 PF04889.12 RKO98837.1 - 9.9 5.8 7.3 24 4.6 7.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_Rpb1_5 PF04998.17 RKO98838.1 - 5.9e-82 275.1 0.1 8.7e-82 274.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 RKO98838.1 - 1.2e-75 254.8 0.0 1.7e-75 254.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 RKO98838.1 - 7e-73 244.3 0.1 1.2e-72 243.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RKO98838.1 - 2.2e-32 112.1 0.0 5.2e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RKO98838.1 - 5.9e-30 103.4 0.0 1.3e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 HPTransfase PF10090.9 RKO98838.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphotransferase C-terminal domain Dpy-30 PF05186.13 RKO98839.1 - 5.4e-09 35.6 0.1 8e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif Cullin PF00888.22 RKO98840.1 - 0.00024 19.8 0.0 0.00035 19.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Epiglycanin_C PF14654.6 RKO98840.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Ank_2 PF12796.7 RKO98843.1 - 9.9e-19 67.7 2.4 4.9e-10 39.9 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKO98843.1 - 6.2e-13 49.0 0.4 8.1e-08 32.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKO98843.1 - 3e-08 33.3 1.9 0.0059 17.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 RKO98843.1 - 5e-07 29.9 8.0 0.00055 20.3 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 RKO98843.1 - 2.2e-06 27.9 4.4 0.0046 17.2 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) TFIIS_C PF01096.18 RKO98844.1 - 4.5e-12 45.6 13.7 1.1e-11 44.4 2.0 3.3 4 0 0 4 4 4 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 RKO98844.1 - 2.7e-09 36.7 2.8 2.7e-09 36.7 2.8 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 RKO98844.1 - 3.1e-05 23.9 3.6 0.0015 18.5 1.0 2.5 2 0 0 2 2 2 2 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 RKO98844.1 - 0.013 15.9 0.3 0.013 15.9 0.3 2.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 RKO98844.1 - 0.022 14.8 4.9 0.21 11.6 0.6 2.6 3 0 0 3 3 3 0 Double zinc ribbon TniQ PF06527.11 RKO98844.1 - 0.062 14.0 1.7 0.077 13.7 1.7 1.3 1 1 0 1 1 1 0 TniQ CpXC PF14353.6 RKO98844.1 - 0.066 13.3 3.2 0.83 9.7 0.3 2.3 2 0 0 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 RKO98844.1 - 0.19 11.7 8.8 0.26 11.3 1.8 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 RKO98844.1 - 0.97 9.6 6.8 12 6.1 0.1 3.5 4 0 0 4 4 4 0 Zinc ribbon domain MutS_V PF00488.21 RKO98845.1 - 5.5e-33 114.6 0.0 9.1e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKO98845.1 - 0.00066 20.0 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain III AAA_16 PF13191.6 RKO98845.1 - 0.027 14.9 1.5 1.4 9.2 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 RKO98845.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 RKO98846.1 - 8e-75 251.6 0.0 9.3e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98846.1 - 5.2e-36 124.3 0.0 7.9e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO98846.1 - 3.1e-06 26.7 0.0 2.4e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKO98846.1 - 0.00046 19.2 0.0 0.00091 18.3 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 RKO98846.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RKO98846.1 - 0.0022 17.9 0.5 0.0078 16.2 0.0 2.1 2 2 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 RKO98846.1 - 0.0023 17.6 0.2 0.27 10.8 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 RKO98846.1 - 0.057 12.8 0.2 0.11 11.8 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO98846.1 - 0.073 11.8 0.0 0.13 11.0 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 RKO98846.1 - 0.16 11.6 0.1 2.6 7.6 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase GalKase_gal_bdg PF10509.9 RKO98847.1 - 1.1e-20 72.9 0.0 2.8e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 RKO98847.1 - 4.6e-15 55.8 0.0 1.2e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 RKO98847.1 - 2.1e-13 50.3 5.3 7.6e-13 48.5 5.3 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain RNase_II_C_S1 PF18614.1 RKO98847.1 - 0.15 12.0 1.8 0.2 11.6 0.2 2.0 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain PTH2 PF01981.16 RKO98848.1 - 2e-15 57.1 0.0 3.1e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GalKase_gal_bdg PF10509.9 RKO98848.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Cyclin_N PF00134.23 RKO98849.1 - 0.041 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain eIF-3_zeta PF05091.12 RKO98850.1 - 1.8e-169 565.1 0.0 2.1e-169 564.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HipN PF18253.1 RKO98850.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain NARG2_C PF10505.9 RKO98850.1 - 0.21 11.1 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus UQ_con PF00179.26 RKO98851.1 - 1.6e-45 154.2 0.0 2e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.29 RKO98852.1 - 1e-24 87.3 0.0 1.8e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98852.1 - 8.3e-12 45.4 0.0 1.7e-08 34.8 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UPF0004 PF00919.20 RKO98853.1 - 1.6e-16 60.2 0.0 4.8e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 RKO98853.1 - 2.1e-16 60.7 0.0 9.2e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily DUF374 PF04028.13 RKO98853.1 - 0.015 14.8 0.0 0.054 13.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Glyco_hydro_26 PF02156.15 RKO98854.1 - 3.7e-11 43.0 0.6 5.4e-05 22.8 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 ETRAMP PF09716.10 RKO98854.1 - 0.097 12.7 0.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Elf1 PF05129.13 RKO98856.1 - 4.4e-30 103.6 0.8 5.4e-30 103.3 0.8 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 RKO98856.1 - 0.00042 19.6 0.5 0.00077 18.8 0.5 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF4432 PF14486.6 RKO98856.1 - 0.033 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) GATA PF00320.27 RKO98856.1 - 0.035 13.7 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 GATA zinc finger zf-Sec23_Sec24 PF04810.15 RKO98856.1 - 0.25 11.4 2.2 0.46 10.6 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Prefoldin PF02996.17 RKO98857.1 - 4.5e-10 39.5 0.0 9.5e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 RKO98857.1 - 8.2e-05 23.4 2.5 2.1 9.2 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 RKO98857.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Prefoldin subunit Stn1 PF10451.9 RKO98858.1 - 4.7e-08 32.3 0.0 7.2e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 RKO98858.1 - 1.1e-06 28.6 0.1 2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SpoIIIAH PF12685.7 RKO98858.1 - 4.5 7.1 8.7 7.7 6.3 3.2 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Microvir_J PF04726.13 RKO98859.1 - 2.9 7.9 6.8 0.46 10.5 2.2 2.0 2 0 0 2 2 2 0 Microvirus J protein IQ PF00612.27 RKO98860.1 - 8.5e-06 25.1 12.2 0.12 12.2 1.4 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif VWA_N PF08399.11 RKO98860.1 - 0.0028 18.1 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 VWA N-terminal CLASP_N PF12348.8 RKO98861.1 - 6.3e-24 84.8 2.2 8.2e-07 28.8 0.1 4.5 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 RKO98861.1 - 2e-11 43.1 23.5 1.3 9.5 0.0 14.5 15 0 0 15 15 15 1 HEAT repeat Cnd1 PF12717.7 RKO98861.1 - 2.2e-09 37.6 8.7 0.49 10.4 0.3 7.4 8 1 0 8 8 8 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKO98861.1 - 2.9e-05 24.4 41.9 0.087 13.2 0.3 10.4 7 4 4 11 11 11 4 HEAT repeats Proteasom_PSMB PF10508.9 RKO98861.1 - 0.081 11.4 9.3 0.088 11.3 0.1 4.1 5 1 0 5 5 5 0 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 RKO98861.1 - 0.12 12.6 5.8 12 6.1 0.1 4.9 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 RKO98861.1 - 0.18 11.9 1.9 2.7 8.1 0.1 3.5 4 0 0 4 4 4 0 Parkin co-regulated protein HEAT_EZ PF13513.6 RKO98861.1 - 0.2 12.2 21.6 25 5.5 0.0 10.3 10 2 3 13 13 13 0 HEAT-like repeat TAN PF11640.8 RKO98861.1 - 0.4 10.8 3.1 3.6 7.7 0.0 4.0 4 1 0 4 4 4 0 Telomere-length maintenance and DNA damage repair WD40 PF00400.32 RKO98862.1 - 2.4e-08 34.5 6.9 2.8e-05 24.8 0.1 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat PD40 PF07676.12 RKO98862.1 - 0.0011 18.9 0.0 0.51 10.3 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 RKO98862.1 - 0.042 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 RKO98862.1 - 0.082 12.6 0.0 17 5.2 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 RKO98862.1 - 0.088 11.7 0.1 1.7 7.6 0.1 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 RKO98862.1 - 0.19 12.1 0.0 4.2 7.7 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3605 PF12239.8 RKO98863.1 - 8.8e-18 65.1 0.0 3.5e-15 56.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) eIF2A PF08662.11 RKO98864.1 - 1.9e-72 243.3 0.0 3.7e-71 239.0 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 RKO98864.1 - 0.0045 17.3 0.0 5.3 7.4 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 RKO98864.1 - 0.085 12.6 4.0 5.7 6.7 0.0 3.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Aminotran_5 PF00266.19 RKO98865.1 - 4.3e-29 101.6 0.0 5.2e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 RKO98865.1 - 0.0062 16.6 0.3 0.43 10.6 0.1 2.4 2 0 0 2 2 2 1 B12 binding domain Ub-Mut7C PF14451.6 RKO98865.1 - 0.013 15.3 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 Mut7-C ubiquitin Vps53_N PF04100.12 RKO98866.1 - 7.9e-72 242.3 0.0 1.1e-71 241.8 0.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 RKO98866.1 - 1.8e-05 23.4 0.2 0.0087 14.5 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec6 VPS53_C PF16854.5 RKO98866.1 - 0.0028 17.6 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Zw10 PF06248.13 RKO98866.1 - 0.0036 15.9 0.9 0.006 15.2 0.9 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 RecG_N PF17190.4 RKO98866.1 - 0.0058 17.3 0.3 0.018 15.7 0.3 1.9 1 0 0 1 1 1 1 RecG N-terminal helical domain Sec20 PF03908.13 RKO98866.1 - 0.0075 16.2 1.3 0.029 14.3 1.3 2.1 1 0 0 1 1 1 1 Sec20 NPV_P10 PF05531.12 RKO98866.1 - 0.011 16.1 2.0 0.011 16.1 2.0 3.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2451 PF10474.9 RKO98866.1 - 0.065 13.0 0.1 0.32 10.8 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Med23 PF11573.8 RKO98866.1 - 0.1 10.2 0.1 0.15 9.7 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 Npa1 PF11707.8 RKO98866.1 - 0.18 11.2 1.5 9.2 5.5 0.8 2.5 3 0 0 3 3 3 0 Ribosome 60S biogenesis N-terminal Vps54_N PF10475.9 RKO98866.1 - 0.19 11.0 2.0 0.37 10.0 2.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex XhlA PF10779.9 RKO98866.1 - 0.67 10.2 4.9 0.23 11.7 1.8 1.9 2 0 0 2 2 1 0 Haemolysin XhlA SSP160 PF06933.11 RKO98867.1 - 0.1 10.8 14.1 0.15 10.3 14.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TIM21 PF08294.11 RKO98867.1 - 0.26 11.2 0.3 0.46 10.4 0.3 1.3 1 0 0 1 1 1 0 TIM21 Ion_trans PF00520.31 RKO98868.1 - 7.1e-24 84.4 20.1 9.4e-24 84.0 20.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RKO98868.1 - 1.8e-05 24.6 5.7 6.6e-05 22.8 3.7 2.4 2 0 0 2 2 2 1 Ion channel PKD_channel PF08016.12 RKO98868.1 - 0.3 9.7 11.4 0.62 8.7 11.4 1.5 1 1 0 1 1 1 0 Polycystin cation channel UQ_con PF00179.26 RKO98870.1 - 1.5e-21 76.5 0.0 1.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKO98870.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B GYF PF02213.16 RKO98871.1 - 4e-15 55.2 3.3 6.9e-15 54.4 3.3 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 RKO98871.1 - 0.0045 16.8 1.1 0.01 15.6 1.1 1.6 1 0 0 1 1 1 1 GYF domain 2 DUF4611 PF15387.6 RKO98872.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) UPF0172 PF03665.13 RKO98873.1 - 2.1e-18 67.0 0.0 3.5e-10 40.3 0.0 3.6 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0172) Motile_Sperm PF00635.26 RKO98874.1 - 3.7e-20 71.8 0.0 4.5e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 RKO98874.1 - 0.0024 18.0 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HSP20 PF00011.21 RKO98875.1 - 3e-07 30.5 0.2 0.00024 21.2 0.0 3.3 1 1 2 4 4 4 2 Hsp20/alpha crystallin family DUF3841 PF12952.7 RKO98875.1 - 0.002 18.0 0.2 1.1 9.0 0.1 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF3841) Vma12 PF11712.8 RKO98875.1 - 0.063 13.4 1.5 0.13 12.4 0.1 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CS PF04969.16 RKO98875.1 - 0.069 14.2 0.0 0.81 10.7 0.0 2.4 2 1 0 2 2 2 0 CS domain Fumble PF03630.14 RKO98878.1 - 4e-130 433.8 0.2 7.3e-130 433.0 0.2 1.4 1 1 0 1 1 1 1 Fumble DUF89 PF01937.19 RKO98878.1 - 9.9e-32 110.3 0.0 1.5e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Tcp10_C PF07202.13 RKO98879.1 - 1.1e-41 142.7 0.1 1.6e-41 142.2 0.1 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus HCBP_related PF06594.11 RKO98879.1 - 0.011 15.7 0.1 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain FlxA PF14282.6 RKO98879.1 - 0.12 12.4 4.0 0.18 11.8 0.5 2.2 2 0 0 2 2 2 0 FlxA-like protein Spc29 PF17082.5 RKO98879.1 - 0.26 11.1 7.0 0.4 10.5 4.5 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF4407 PF14362.6 RKO98879.1 - 3.1 7.1 10.6 5.5 6.3 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 RKO98879.1 - 9.1 5.1 17.5 21 3.8 17.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2207 PF09972.9 RKO98880.1 - 0.0061 15.4 1.4 0.0068 15.2 1.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 RKO98880.1 - 0.068 12.5 7.3 0.08 12.3 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DHHC PF01529.20 RKO98880.1 - 0.35 11.0 1.9 0.51 10.4 1.9 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3043 PF11241.8 RKO98880.1 - 8.6 6.4 9.6 10 6.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) HSP20 PF00011.21 RKO98881.1 - 7e-07 29.3 0.0 8.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family bZIP_1 PF00170.21 RKO98882.1 - 1.6e-09 37.7 6.4 2.8e-09 36.9 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RKO98882.1 - 2e-08 34.2 9.9 3.6e-08 33.4 9.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RKO98882.1 - 0.00036 21.0 2.4 0.0063 17.0 4.5 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Cep57_CLD_2 PF14197.6 RKO98882.1 - 0.011 15.7 0.3 0.027 14.6 0.3 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ParA PF10609.9 RKO98884.1 - 3e-94 315.1 0.0 3.8e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RKO98884.1 - 1.7e-11 44.3 0.0 7e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 RKO98884.1 - 2.5e-08 34.0 0.1 2.4e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 RKO98884.1 - 7.2e-08 32.0 0.3 1.9e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 RKO98884.1 - 5.9e-06 25.7 2.3 8.8e-06 25.1 0.3 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 RKO98884.1 - 5.8e-05 22.2 0.5 0.00012 21.1 0.5 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 RKO98884.1 - 0.00012 21.7 0.1 0.00032 20.3 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 RKO98884.1 - 0.0022 17.8 0.3 0.93 9.3 0.2 2.2 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 RKO98884.1 - 0.0041 16.9 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_NifH PF00142.18 RKO98884.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 RKO98884.1 - 0.018 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 RKO98884.1 - 0.071 12.7 0.1 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 RKO98884.1 - 0.076 12.6 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RKO98884.1 - 0.089 12.5 0.1 0.43 10.3 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 RKO98884.1 - 0.15 12.0 0.2 0.47 10.3 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase zf-C2H2 PF00096.26 RKO98885.1 - 2.2e-12 46.7 16.2 0.00015 22.0 0.1 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RKO98885.1 - 1.2e-10 41.4 1.6 0.0039 17.4 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 RKO98885.1 - 1.7e-10 40.8 9.7 1.7e-06 28.2 1.2 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO98885.1 - 4.8e-10 39.4 14.5 0.0041 17.8 3.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 RKO98885.1 - 5.9e-06 26.5 4.6 0.035 14.5 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.15 RKO98885.1 - 0.0019 18.2 4.9 0.66 10.0 1.7 2.7 2 1 1 3 3 3 2 BED zinc finger C1_4 PF07975.12 RKO98885.1 - 0.0038 17.4 1.4 0.12 12.6 0.2 2.1 2 0 0 2 2 2 1 TFIIH C1-like domain zf-C2H2_11 PF16622.5 RKO98885.1 - 0.015 15.0 6.1 1.1 9.1 0.2 2.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 RKO98885.1 - 0.033 14.2 0.2 0.033 14.2 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger RIG-I_C-RD PF11648.8 RKO98885.1 - 0.11 12.7 0.6 3 8.1 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-CHY PF05495.12 RKO98885.1 - 0.13 12.8 9.4 0.49 10.9 2.9 2.3 1 1 1 2 2 2 0 CHY zinc finger zf-C2H2_2 PF12756.7 RKO98885.1 - 0.14 12.5 4.5 0.89 9.9 0.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) XPA_N PF01286.18 RKO98885.1 - 0.15 12.1 4.9 2.8 8.0 0.2 2.7 3 0 0 3 3 3 0 XPA protein N-terminal zf-AN1 PF01428.16 RKO98885.1 - 0.27 11.4 9.8 5 7.4 3.8 2.8 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 RKO98885.1 - 0.3 11.6 9.9 2.2 8.8 3.6 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 RKO98885.1 - 0.61 10.0 0.1 0.61 10.0 0.1 3.0 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-MYST PF17772.1 RKO98885.1 - 0.99 9.1 6.6 0.15 11.7 1.3 2.2 2 1 0 2 2 2 0 MYST family zinc finger domain Zn_Tnp_IS1595 PF12760.7 RKO98885.1 - 3.6 7.6 8.8 3.3 7.8 4.5 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UQ_con PF00179.26 RKO98887.1 - 1e-17 64.1 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM92 PF06730.11 RKO98889.1 - 1.1e-12 47.8 2.7 1.9e-12 47.1 2.7 1.3 1 0 0 1 1 1 1 FAM92 protein DUF1387 PF07139.11 RKO98889.1 - 0.015 15.0 3.6 0.036 13.8 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SUIM_assoc PF16619.5 RKO98889.1 - 0.052 13.6 6.4 0.21 11.7 6.4 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ArsA_ATPase PF02374.15 RKO98889.1 - 0.058 12.6 0.2 0.058 12.6 0.2 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase DUF4887 PF16228.5 RKO98889.1 - 0.84 9.8 15.1 1.8 8.8 15.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Spt20 PF12090.8 RKO98889.1 - 4.5 6.8 12.6 7.4 6.1 12.6 1.3 1 0 0 1 1 1 0 Spt20 family RRM_1 PF00076.22 RKO98890.1 - 1.7e-46 155.9 0.1 1.8e-13 50.1 0.0 5.8 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO98890.1 - 3.7e-05 23.8 0.0 0.94 9.6 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif DUF4078 PF13300.6 RKO98890.1 - 0.057 13.7 1.0 3 8.2 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4078) MCM_bind PF09739.9 RKO98890.1 - 0.096 11.1 1.7 0.14 10.5 1.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MAM33 PF02330.16 RKO98890.1 - 2.1 8.2 8.4 2.4 8.1 4.9 2.3 2 0 0 2 2 2 0 Mitochondrial glycoprotein SAPS PF04499.15 RKO98890.1 - 6.9 5.3 5.8 9.5 4.9 5.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.8 RKO98890.1 - 8.2 6.6 13.0 4 7.6 9.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ANAPC4_WD40 PF12894.7 RKO98891.1 - 3.4e-08 33.7 0.1 0.056 13.7 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_11 PF13414.6 RKO98891.1 - 0.014 15.1 1.3 1.7 8.4 0.5 2.7 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 RKO98891.1 - 0.034 14.2 0.3 1.6 9.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO98891.1 - 0.04 14.0 10.0 0.06 13.5 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RKO98891.1 - 0.068 13.4 6.6 6.9 7.2 0.4 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 RKO98891.1 - 0.084 13.8 0.1 0.67 10.9 0.1 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Vps16_N PF04841.13 RKO98891.1 - 0.095 11.4 0.0 7.6 5.2 0.0 2.6 3 0 0 3 3 3 0 Vps16, N-terminal region TPR_1 PF00515.28 RKO98891.1 - 0.38 10.6 8.3 0.37 10.7 0.4 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 RKO98891.1 - 0.41 10.7 3.8 9.5 6.4 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 RKO98891.1 - 0.63 10.4 14.9 0.065 13.5 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO98891.1 - 3.3 8.5 9.2 9.7 7.1 0.7 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Ras PF00071.22 RKO98892.1 - 3.8e-42 143.6 0.0 4.3e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO98892.1 - 3.3e-18 66.0 0.0 5.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO98892.1 - 5.9e-07 29.1 0.0 7.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO98892.1 - 0.00012 21.7 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RKO98892.1 - 0.0015 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Lar_N PF09861.9 RKO98892.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain ATP_bind_3 PF01171.20 RKO98893.1 - 2.3e-06 27.5 0.1 7e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 PP-loop family DUF4157 PF13699.6 RKO98893.1 - 0.2 11.9 4.2 9.2 6.6 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) DUF2785 PF10978.8 RKO98893.1 - 0.2 11.4 0.3 13 5.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) Cyto_heme_lyase PF01265.17 RKO98894.1 - 6.4e-60 203.2 14.4 3e-57 194.4 14.4 2.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase vATP-synt_E PF01991.18 RKO98896.1 - 8.3e-59 198.3 10.8 9.6e-59 198.1 10.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit CEP19 PF14933.6 RKO98896.1 - 0.53 10.6 6.8 1.1 9.6 3.9 2.1 2 0 0 2 2 2 0 CEP19-like protein DUF4889 PF16230.5 RKO98896.1 - 1.7 8.9 4.4 5.2 7.4 3.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4889) Mannosyl_trans4 PF15971.5 RKO98897.1 - 0.022 14.6 0.4 0.022 14.6 0.4 1.9 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase DUF2009 PF09418.10 RKO98898.1 - 1.2e-194 647.6 0.0 1.6e-194 647.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 RKO98898.1 - 8.5e-06 25.8 4.7 2.1e-05 24.6 4.7 1.7 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 RKO98898.1 - 0.00014 22.0 6.1 0.00032 20.9 6.1 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-HIT PF04438.16 RKO98898.1 - 0.17 11.8 5.1 0.43 10.5 5.1 1.8 1 0 0 1 1 1 0 HIT zinc finger zf-C3HC4_3 PF13920.6 RKO98898.1 - 0.49 10.3 5.2 1.1 9.2 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 RKO98898.1 - 1.3 9.3 7.8 0.33 11.2 4.1 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 RKO98898.1 - 8.1 6.7 10.1 77 3.5 10.5 2.2 1 1 1 2 2 2 0 FYVE zinc finger RibD_C PF01872.17 RKO98899.1 - 1.6e-19 70.5 0.2 2e-11 44.1 0.1 2.2 2 0 0 2 2 2 2 RibD C-terminal domain DUF5638 PF18688.1 RKO98900.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Thioredoxin PF00085.20 RKO98901.1 - 3e-20 72.1 0.1 3.2e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 RKO98901.1 - 1.5e-07 31.5 0.3 2.7e-07 30.7 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 RKO98901.1 - 7.6e-06 26.2 0.1 0.063 13.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO98901.1 - 2.5e-05 24.7 0.6 0.0003 21.2 0.6 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RKO98901.1 - 8.1e-05 22.6 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 RKO98901.1 - 0.031 14.2 0.1 0.74 9.7 0.0 2.0 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.6 RKO98901.1 - 0.056 13.2 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin KaiB PF07689.12 RKO98901.1 - 0.062 13.0 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 KaiB domain OST3_OST6 PF04756.13 RKO98901.1 - 0.07 12.5 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DIM1 PF02966.16 RKO98902.1 - 4.4e-66 220.7 0.1 5e-66 220.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 RKO98902.1 - 1.5e-05 24.9 0.0 1.9e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin RhoGAP PF00620.27 RKO98903.1 - 1.6e-25 89.7 0.0 1.2e-24 86.9 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain MLTR_LBD PF17765.1 RKO98903.1 - 0.33 11.1 2.1 17 5.5 0.1 3.3 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain FAD_binding_2 PF00890.24 RKO98904.1 - 6.3e-76 256.1 3.4 7.6e-76 255.8 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 RKO98904.1 - 1.2e-17 63.8 0.2 3.1e-17 62.5 0.0 1.8 2 0 0 2 2 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 RKO98904.1 - 2.5e-14 53.7 1.9 5.8e-14 52.4 1.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RKO98904.1 - 9.6e-09 35.4 3.3 2.9e-08 33.8 0.3 3.1 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RKO98904.1 - 1.9e-08 34.1 2.1 1.9e-08 34.1 2.1 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 RKO98904.1 - 8.6e-08 31.9 3.0 5.1e-05 22.7 0.3 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 RKO98904.1 - 2.8e-06 26.8 1.6 0.00033 20.0 0.7 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKO98904.1 - 5.5e-06 25.9 2.4 9.1e-06 25.1 2.4 1.4 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 RKO98904.1 - 7.9e-05 22.0 0.5 0.002 17.4 0.2 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 RKO98904.1 - 8.4e-05 23.1 0.7 0.00098 19.6 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RKO98904.1 - 0.00013 20.8 2.5 0.00069 18.4 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 RKO98904.1 - 0.00044 19.4 2.3 0.00047 19.4 1.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RKO98904.1 - 0.012 14.6 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 RKO98904.1 - 0.03 13.6 0.7 0.058 12.7 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 RKO98904.1 - 0.051 13.6 0.2 0.21 11.5 0.2 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 RKO98904.1 - 0.061 12.6 0.1 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CNH PF00780.22 RKO98905.1 - 1e-61 209.0 0.0 1.6e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 RKO98905.1 - 1.1e-36 126.8 0.0 1.6e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 RKO98905.1 - 1.2e-17 64.3 0.0 2.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 RKO98905.1 - 3.6e-13 49.4 0.0 7.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 RKO98905.1 - 7.8e-05 22.5 0.0 0.00091 19.1 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 RKO98905.1 - 0.0003 21.2 0.0 0.00063 20.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 RKO98905.1 - 0.01 15.7 0.0 0.19 11.6 0.1 2.5 2 0 0 2 2 2 0 PH domain SpoIIE PF07228.12 RKO98906.1 - 1.8e-12 47.6 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 RKO98906.1 - 3.4e-10 40.0 0.0 2.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 RKO98906.1 - 9.4e-05 22.1 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C HEAT_2 PF13646.6 RKO98907.1 - 6.9 7.1 10.7 1.9 9.0 0.1 4.1 3 0 0 3 3 3 0 HEAT repeats FixS PF03597.15 RKO98909.1 - 0.28 10.9 0.9 0.49 10.1 0.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Cyt-b5 PF00173.28 RKO98910.1 - 1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NARP1 PF12569.8 RKO98911.1 - 5.4e-98 329.1 5.1 5.4e-98 329.1 5.1 1.5 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 RKO98911.1 - 3.7e-12 45.4 44.9 4.8e-05 23.2 0.0 9.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 RKO98911.1 - 4.1e-10 39.1 8.2 0.0015 18.6 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKO98911.1 - 1.2e-09 38.5 34.5 0.001 19.5 7.8 6.5 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 RKO98911.1 - 5.2e-08 33.1 54.8 0.00082 20.0 2.7 10.6 8 3 3 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98911.1 - 7e-08 32.0 16.5 0.00039 20.1 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO98911.1 - 1.1e-07 32.4 59.6 1.5e-05 25.5 6.3 8.0 7 2 1 9 9 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 RKO98911.1 - 2.8e-07 30.7 20.3 1.2 9.9 0.1 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 RKO98911.1 - 6.3e-07 29.0 12.8 0.0075 16.2 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKO98911.1 - 0.0002 21.4 5.5 0.045 13.8 0.1 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 RKO98911.1 - 0.002 17.7 4.5 0.0048 16.5 0.0 3.6 5 0 0 5 5 5 1 TPR repeat TPR_12 PF13424.6 RKO98911.1 - 0.04 14.2 0.1 0.04 14.2 0.1 7.7 7 2 1 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKO98911.1 - 0.061 14.0 0.7 0.061 14.0 0.7 6.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 RKO98911.1 - 0.1 12.7 30.0 0.034 14.3 2.9 6.4 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKO98911.1 - 0.48 10.4 20.7 1 9.3 0.3 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO98911.1 - 1.1 9.8 10.7 6.4 7.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Acyltransferase PF01553.21 RKO98912.1 - 3.5e-11 42.9 0.0 4.3e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase CFAP91 PF14738.6 RKO98913.1 - 5.3e-50 169.4 12.8 5.3e-50 169.4 12.8 3.0 3 0 0 3 3 3 1 Cilia- and flagella-associated protein 91 TP_methylase PF00590.20 RKO98913.1 - 0.026 14.5 0.1 0.12 12.3 0.1 2.1 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2590 PF10761.9 RKO98913.1 - 0.12 12.5 2.0 0.33 11.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2590) AMP-binding PF00501.28 RKO98914.1 - 1.4e-88 297.3 0.1 1.9e-88 296.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO98914.1 - 0.00061 20.7 0.7 0.0015 19.4 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PEX11 PF05648.14 RKO98915.1 - 1.4e-19 70.4 0.2 7.7e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) F-box-like PF12937.7 RKO98916.1 - 8.1e-10 38.4 0.2 1.9e-09 37.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RKO98916.1 - 2e-07 30.7 0.0 5.7e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 F-box domain LisH_2 PF16045.5 RKO98916.1 - 3e-07 29.3 0.0 4.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 LisH LRR_6 PF13516.6 RKO98916.1 - 0.00064 19.6 1.2 38 4.7 0.0 6.1 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.7 RKO98916.1 - 0.0033 17.8 0.0 16 6.1 0.0 4.5 4 1 0 5 5 5 1 Leucine Rich repeats (2 copies) CSTF1_dimer PF16699.5 RKO98916.1 - 0.049 13.4 0.1 1.5 8.7 0.0 2.9 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain Cpn60_TCP1 PF00118.24 RKO98917.1 - 2.3e-169 564.2 0.4 2.6e-169 564.0 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box PF00646.33 RKO98918.1 - 0.026 14.4 0.3 0.078 12.9 0.3 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 RKO98918.1 - 0.052 13.5 0.8 0.15 11.9 0.8 1.8 1 0 0 1 1 1 0 F-box-like HMG_box PF00505.19 RKO98919.1 - 6.5e-13 48.9 0.0 8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO98919.1 - 0.0037 17.8 0.0 0.0052 17.3 0.0 1.2 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 RKO98919.1 - 0.062 12.6 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Lipase_3 PF01764.25 RKO98920.1 - 2.8e-13 49.9 0.0 8.2e-13 48.4 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 RKO98920.1 - 0.041 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2992 PF11208.8 RKO98920.1 - 0.27 11.5 0.0 0.54 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Hydrophobin PF01185.18 RKO98921.1 - 3.4e-10 40.4 10.2 4.3e-10 40.1 10.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ribosomal_S26e PF01283.19 RKO98924.1 - 7.5e-53 177.5 10.4 8.6e-53 177.3 10.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 RKO98924.1 - 0.025 15.1 2.4 1.3 9.7 1.1 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Rep_fac_C PF08542.11 RKO98925.1 - 1.7e-19 70.0 0.0 7.6e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 RKO98925.1 - 4.4e-15 56.3 0.0 8.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RKO98925.1 - 2.2e-14 53.5 0.0 1.1e-10 41.6 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 RKO98925.1 - 3.8e-07 30.2 0.0 9.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain DUF815 PF05673.13 RKO98925.1 - 1.8e-05 24.0 0.0 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 RKO98925.1 - 6.4e-05 23.4 0.0 0.00014 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 RKO98925.1 - 0.00012 22.4 0.0 0.00031 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 RKO98925.1 - 0.00014 21.9 0.0 0.00033 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO98925.1 - 0.00015 21.6 0.0 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 RKO98925.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 RKO98925.1 - 0.00032 20.6 0.1 0.0023 17.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RKO98925.1 - 0.00058 19.9 0.1 0.005 16.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO98925.1 - 0.00078 19.7 0.3 1.6 9.0 0.1 2.6 1 1 1 2 2 2 2 AAA domain TniB PF05621.11 RKO98925.1 - 0.00085 18.8 0.0 0.019 14.4 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein ResIII PF04851.15 RKO98925.1 - 0.00093 19.2 0.0 0.07 13.1 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 RKO98925.1 - 0.0018 18.1 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 RKO98925.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 RKO98925.1 - 0.0024 17.6 0.0 0.0098 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RKO98925.1 - 0.0041 17.5 0.0 0.014 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 RKO98925.1 - 0.0084 15.9 0.0 0.092 12.5 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 RKO98925.1 - 0.0092 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 RKO98925.1 - 0.053 13.3 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit IstB_IS21 PF01695.17 RKO98925.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.23 RKO98925.1 - 0.1 11.3 0.0 0.49 9.1 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain PXA PF02194.15 RKO98926.1 - 5.7e-30 104.6 0.2 3.2e-27 95.7 0.0 2.9 2 0 0 2 2 2 2 PXA domain Nexin_C PF08628.12 RKO98926.1 - 1.9e-17 63.8 0.2 8.8e-08 32.7 0.0 3.1 2 0 0 2 2 2 2 Sorting nexin C terminal Rpr2 PF04032.16 RKO98927.1 - 1.7e-19 69.9 1.4 3.6e-18 65.6 1.2 2.4 2 1 1 3 3 3 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mod_r PF07200.13 RKO98928.1 - 3.2e-18 66.2 0.0 4.6e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 RKO98928.1 - 0.0031 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKO98928.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain DHHC PF01529.20 RKO98929.1 - 1.7e-34 118.8 3.3 1.9e-34 118.6 3.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF308 PF03729.13 RKO98929.1 - 0.093 13.1 7.1 0.33 11.3 6.7 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Exo_endo_phos PF03372.23 RKO98930.1 - 1.2e-11 44.6 1.5 1.5e-11 44.3 1.5 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyocin_S PF06958.12 RKO98930.1 - 0.12 13.0 0.6 0.21 12.1 0.6 1.4 1 0 0 1 1 1 0 S-type Pyocin UPF0086 PF01868.16 RKO98931.1 - 8.2e-25 86.5 0.0 1.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DHFR_2 PF06442.11 RKO98931.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 R67 dihydrofolate reductase FAM72 PF14976.6 RKO98932.1 - 6e-16 58.9 0.2 1.6e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 FAM72 protein YL1 PF05764.13 RKO98933.1 - 3.5e-07 30.6 4.0 3.4e-06 27.4 4.0 2.8 1 1 0 1 1 1 1 YL1 nuclear protein Dehydrin PF00257.19 RKO98933.1 - 8 7.0 7.3 5.2 7.6 5.2 1.8 2 0 0 2 2 2 0 Dehydrin Inositol_P PF00459.25 RKO98934.1 - 1.4e-60 205.1 0.1 1.6e-60 205.0 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Annexin PF00191.20 RKO98935.1 - 3.7e-79 260.7 0.2 1.3e-23 82.8 0.0 4.1 4 0 0 4 4 4 4 Annexin Abhydrolase_2 PF02230.16 RKO98936.1 - 4.8e-66 222.7 0.0 5.4e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RKO98936.1 - 3.3e-09 36.4 0.1 5.2e-06 25.9 0.0 3.0 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 RKO98936.1 - 1.7e-07 31.1 0.0 7.1e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 RKO98936.1 - 4e-06 26.5 0.0 0.00017 21.1 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 RKO98936.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 RKO98936.1 - 2.5e-05 25.0 4.3 9.8e-05 23.1 2.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RKO98936.1 - 0.00096 19.1 0.0 0.15 11.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Cutinase PF01083.22 RKO98936.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase zf-RING_2 PF13639.6 RKO98937.1 - 4.1e-16 59.0 8.6 5.2e-16 58.7 8.6 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RKO98937.1 - 3e-12 46.0 2.3 3e-12 46.0 2.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RKO98937.1 - 2.3e-11 43.4 7.0 3e-11 43.0 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO98937.1 - 2.4e-09 37.1 2.0 2.4e-09 37.1 2.0 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RKO98937.1 - 5.7e-09 36.1 9.7 1.7e-08 34.6 9.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO98937.1 - 9.3e-09 35.1 6.0 1.2e-08 34.8 6.0 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RKO98937.1 - 1.4e-08 34.5 7.4 1.9e-08 34.1 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKO98937.1 - 2.4e-07 30.5 6.1 3.1e-07 30.2 6.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKO98937.1 - 4.2e-05 23.3 5.2 6.2e-05 22.8 5.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RKO98937.1 - 0.00011 21.7 5.4 0.00017 21.1 5.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 RKO98937.1 - 0.00023 21.2 5.3 0.00052 20.1 5.3 1.6 1 1 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 RKO98937.1 - 0.0012 18.9 8.1 0.0082 16.2 8.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 RKO98937.1 - 0.0046 17.2 5.2 0.0064 16.8 5.2 1.2 1 0 0 1 1 1 1 RING-like domain Zf_RING PF16744.5 RKO98937.1 - 0.0071 16.4 3.1 0.0071 16.4 3.1 1.4 1 1 0 1 1 1 1 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 RKO98937.1 - 0.019 15.1 5.3 0.057 13.6 5.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 RKO98937.1 - 0.038 13.9 4.6 0.067 13.1 4.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 RKO98937.1 - 0.044 13.6 5.1 0.064 13.1 5.1 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RKO98937.1 - 0.085 12.7 2.3 0.13 12.2 2.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_RING PF05883.11 RKO98937.1 - 0.1 12.6 0.6 0.13 12.2 0.6 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 RKO98937.1 - 0.18 11.7 3.8 0.34 10.7 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RKO98937.1 - 0.91 9.7 9.2 4.2 7.6 9.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain dCMP_cyt_deam_1 PF00383.23 RKO98939.1 - 5.9e-15 55.0 0.2 6.9e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 RKO98939.1 - 3.5e-10 40.2 2.3 1.3e-09 38.4 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 RKO98939.1 - 0.0072 15.9 0.8 1.1 8.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Pre-PUA PF17832.1 RKO98940.1 - 1.4e-25 89.8 0.2 2.6e-25 88.9 0.2 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 RKO98940.1 - 4.6e-20 71.3 0.1 7e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 PUA domain COPIIcoated_ERV PF07970.12 RKO98941.1 - 2e-86 289.4 0.8 2.4e-86 289.2 0.8 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RKO98941.1 - 3.4e-28 97.8 0.1 1e-27 96.3 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ndc80_HEC PF03801.13 RKO98942.1 - 1.2e-46 158.1 0.0 3.6e-46 156.6 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 RKO98942.1 - 2.2e-09 37.3 0.0 2.2e-09 37.3 0.0 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF5595) Spc7 PF08317.11 RKO98942.1 - 0.0033 16.4 8.5 0.0033 16.4 8.5 2.7 2 1 0 2 2 2 1 Spc7 kinetochore protein IFT57 PF10498.9 RKO98942.1 - 0.088 11.8 25.2 0.042 12.8 3.4 3.0 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 PI_PP_I PF18363.1 RKO98942.1 - 0.095 12.9 6.4 0.1 12.8 0.3 3.2 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF4407 PF14362.6 RKO98942.1 - 0.32 10.3 23.6 0.21 10.9 10.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 RKO98942.1 - 0.39 10.7 30.9 0.027 14.5 6.5 4.0 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 RKO98942.1 - 0.53 9.6 34.7 0.073 12.4 10.4 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 RKO98942.1 - 0.58 10.6 27.4 0.62 10.5 8.4 2.6 2 1 0 2 2 2 0 Fez1 WXG100 PF06013.12 RKO98942.1 - 0.92 9.8 0.0 0.92 9.8 0.0 5.4 5 1 0 5 5 5 0 Proteins of 100 residues with WXG UPF0242 PF06785.11 RKO98942.1 - 0.93 9.6 41.6 1.4 9.0 8.5 4.0 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 RKO98942.1 - 0.99 9.9 15.6 0.038 14.4 3.2 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 RKO98942.1 - 1.4 8.8 20.8 0.032 14.0 1.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF724) OmpH PF03938.14 RKO98942.1 - 3.8 7.8 30.4 1.6 9.0 4.5 3.9 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) COG2 PF06148.11 RKO98942.1 - 4.5 7.4 17.8 0.037 14.1 2.4 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4665 PF15679.5 RKO98942.1 - 4.9 7.8 11.9 0.88 10.2 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) COG5 PF10392.9 RKO98942.1 - 5.3 7.2 20.5 0.14 12.3 4.2 3.0 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Syntaxin PF00804.25 RKO98942.1 - 9.1 5.9 22.7 2.3 7.8 9.4 2.9 2 1 0 2 2 2 0 Syntaxin WD40 PF00400.32 RKO98943.1 - 0.0028 18.5 0.1 0.13 13.1 0.1 3.3 2 1 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98943.1 - 0.031 14.6 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TspO_MBR PF03073.15 RKO98945.1 - 3.3e-36 124.3 15.2 3.9e-36 124.1 15.2 1.0 1 0 0 1 1 1 1 TspO/MBR family CcmF_C PF16327.5 RKO98945.1 - 0.11 11.8 4.9 0.13 11.5 4.9 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal FHA PF00498.26 RKO98947.1 - 1.3e-13 51.1 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 RKO98947.1 - 6.4e-12 45.0 9.1 1.1e-11 44.3 9.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 RKO98947.1 - 4.5e-09 36.5 9.4 6.3e-09 36.0 9.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 RKO98947.1 - 0.00011 22.2 2.0 0.00017 21.6 2.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Yop-YscD_cpl PF16697.5 RKO98947.1 - 0.00022 21.5 0.0 0.00035 20.8 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 RKO98947.1 - 0.00034 20.4 10.0 0.00052 19.8 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO98947.1 - 0.00094 19.0 10.3 0.0015 18.3 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RKO98947.1 - 0.0016 18.7 8.9 0.004 17.4 8.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO98947.1 - 0.015 15.2 10.2 0.045 13.7 10.5 1.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKO98947.1 - 0.019 15.0 6.3 0.019 15.0 6.3 1.8 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.29 RKO98947.1 - 0.24 11.3 6.8 0.39 10.6 6.8 1.4 1 0 0 1 1 1 0 PHD-finger Dynactin_p62 PF05502.13 RKO98947.1 - 0.68 8.6 3.4 0.99 8.1 3.4 1.1 1 0 0 1 1 1 0 Dynactin p62 family WD40 PF00400.32 RKO98948.1 - 1.8e-11 44.4 18.9 0.00022 22.0 0.2 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98948.1 - 0.26 11.6 2.8 12 6.3 0.0 3.3 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKO98949.1 - 0.033 13.8 0.2 0.033 13.8 0.2 2.5 3 0 0 3 3 3 0 PQQ-like domain MRI PF15325.6 RKO98949.1 - 2.3 9.3 0.0 2.3 9.3 0.0 2.9 3 0 0 3 3 3 0 Modulator of retrovirus infection Longin PF13774.6 RKO98951.1 - 9.1e-26 89.7 0.3 1.6e-25 88.9 0.3 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 RKO98951.1 - 2.4e-15 56.1 0.1 4.6e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 RKO98951.1 - 0.036 14.0 0.7 0.086 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein SLM4 YgaB PF14182.6 RKO98951.1 - 0.056 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 YgaB-like protein DUF383 PF04063.14 RKO98952.1 - 2.2e-45 154.7 0.0 1.4e-44 152.1 0.0 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 RKO98952.1 - 2.5e-23 81.7 1.2 3.7e-23 81.1 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF384) CTU2 PF10288.9 RKO98953.1 - 0.003 17.8 0.0 0.017 15.3 0.0 2.2 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 RKO98953.1 - 0.14 11.9 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 PP-loop family DSPc PF00782.20 RKO98954.1 - 0.00057 19.7 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO98954.1 - 0.00069 19.2 0.0 0.00085 19.0 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 RKO98954.1 - 0.059 13.0 1.4 1.3 8.6 0.4 3.1 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Spc24 PF08286.11 RKO98955.1 - 2.5e-15 56.6 0.5 4e-15 55.9 0.5 1.4 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 BRE1 PF08647.11 RKO98955.1 - 0.035 14.2 2.6 0.057 13.5 1.1 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DJ-1_PfpI PF01965.24 RKO98955.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Occludin_ELL PF07303.13 RKO98955.1 - 0.061 14.1 1.2 0.097 13.4 1.2 1.3 1 0 0 1 1 1 0 Occludin homology domain V_ATPase_I PF01496.19 RKO98955.1 - 0.16 9.8 1.0 0.21 9.5 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Asparaginase_2 PF01112.18 RKO98956.1 - 2.5e-13 49.7 8.3 1.1e-06 27.9 0.1 4.8 4 1 1 5 5 5 4 Asparaginase LigB PF02900.18 RKO98957.1 - 1.9e-28 99.3 0.0 2.1e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF2059 PF09832.9 RKO98957.1 - 0.092 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) DUF1206 PF06724.11 RKO98958.1 - 1.3e-20 73.2 14.1 4.5e-11 42.7 0.5 4.3 3 1 0 3 3 3 3 Domain of Unknown Function (DUF1206) Fig1 PF12351.8 RKO98958.1 - 0.26 11.2 3.1 0.086 12.8 0.3 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4013 PF13197.6 RKO98958.1 - 3.5 7.5 12.8 0.04 13.8 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) Virul_fac_BrkB PF03631.15 RKO98958.1 - 4.8 6.7 12.2 0.13 11.9 3.0 2.4 2 1 0 2 2 2 0 Virulence factor BrkB FlgN PF05130.12 RKO98960.1 - 0.0042 17.6 2.1 0.046 14.2 0.1 2.8 2 0 0 2 2 2 1 FlgN protein DUF4600 PF15372.6 RKO98960.1 - 0.4 11.1 5.0 0.4 11.1 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Hap4_Hap_bind PF10297.9 RKO98960.1 - 0.82 9.9 9.6 0.28 11.4 6.1 2.2 1 1 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Cyclin_C_2 PF16899.5 RKO98961.1 - 6.9e-11 42.5 0.3 8.8e-10 38.9 0.1 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 RKO98961.1 - 8.2e-11 41.7 0.3 1.5e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med9 PF07544.13 RKO98962.1 - 3.5e-06 27.0 0.1 5.1e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Ribo_biogen_C PF04034.13 RKO98964.1 - 4.5e-54 181.6 0.0 5.5e-54 181.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 RKO98964.1 - 5.1e-14 51.8 0.3 1.1e-13 50.8 0.3 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SF3b1 PF08920.10 RKO98966.1 - 5.8e-13 49.4 3.6 5.1e-11 43.1 3.6 2.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT PF02985.22 RKO98966.1 - 3.1e-12 45.6 9.9 0.04 14.2 0.1 9.3 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 RKO98966.1 - 3.8e-08 33.6 10.9 2.2 8.7 0.2 7.5 5 2 4 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 RKO98966.1 - 2.5e-07 31.1 9.6 0.15 12.6 0.0 8.1 8 1 2 10 10 10 2 HEAT-like repeat Arm PF00514.23 RKO98966.1 - 0.0036 17.3 0.0 71 3.7 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 RKO98966.1 - 0.014 15.4 1.3 9.2 6.3 0.0 4.7 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RKO98966.1 - 0.047 14.3 0.0 3.5 8.3 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 RKO98966.1 - 0.059 13.3 1.1 8.3 6.3 0.0 4.1 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) DUF4042 PF13251.6 RKO98966.1 - 0.11 12.3 0.1 16 5.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) DRIM PF07539.12 RKO98966.1 - 0.18 10.1 0.4 36 2.5 0.1 3.3 2 2 2 4 4 4 0 Down-regulated in metastasis DUF1899 PF08953.11 RKO98967.1 - 2.5e-31 107.3 0.1 5.1e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 RKO98967.1 - 4.5e-20 71.3 0.1 8.4e-20 70.4 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 RKO98967.1 - 5.3e-17 61.9 1.7 0.00014 22.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98967.1 - 6.8e-06 26.3 0.1 0.0014 18.9 0.0 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4394 PF14339.6 RKO98967.1 - 0.015 14.7 0.2 0.069 12.5 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4394) Cnn_1N PF07989.11 RKO98967.1 - 0.044 13.9 0.2 0.074 13.2 0.2 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ICL PF00463.21 RKO98968.1 - 5.1e-23 81.4 0.0 6e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family CTP_synth_N PF06418.14 RKO98969.1 - 6.3e-126 419.1 0.0 8.4e-126 418.7 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 RKO98969.1 - 9.1e-56 188.6 0.0 1.4e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKO98969.1 - 0.0017 18.2 0.1 0.011 15.5 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 KxDL PF10241.9 RKO98971.1 - 6.6e-09 35.9 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein LRR_4 PF12799.7 RKO98973.1 - 6.9e-16 58.1 20.1 3.7e-08 33.5 0.9 3.9 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RKO98973.1 - 8.9e-15 54.6 6.1 2.3e-14 53.3 3.6 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 RKO98973.1 - 3.3e-12 46.0 18.9 8.6e-07 28.6 0.5 3.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 RKO98973.1 - 0.012 15.6 4.7 2.9 8.2 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat DUF1043 PF06295.12 RKO98973.1 - 0.03 14.3 5.9 0.12 12.4 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) LRR_1 PF00560.33 RKO98973.1 - 0.032 14.8 12.4 11 7.0 0.9 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Serglycin PF04360.12 RKO98974.1 - 0.023 14.6 1.1 0.035 14.0 1.1 1.3 1 0 0 1 1 1 0 Serglycin Sporozoite_P67 PF05642.11 RKO98974.1 - 0.21 9.6 8.3 0.26 9.4 8.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 RKO98974.1 - 0.22 9.6 5.7 0.24 9.5 5.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAM25 PF15825.5 RKO98974.1 - 0.77 10.1 10.7 0.67 10.3 0.4 2.3 2 0 0 2 2 2 0 FAM25 family MSP1_C PF07462.11 RKO98974.1 - 0.81 8.3 4.1 1 7.9 4.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SUIM_assoc PF16619.5 RKO98975.1 - 0.0021 18.1 4.4 0.0054 16.8 4.4 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Nitroreductase PF00881.24 RKO98975.1 - 2.2 8.3 7.2 6.9 6.7 0.3 2.7 2 1 0 3 3 3 0 Nitroreductase family DUF3678 PF12435.8 RKO98976.1 - 0.072 12.5 1.4 0.32 10.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) RRM_1 PF00076.22 RKO98977.1 - 8.9e-79 259.3 0.2 4.8e-19 67.9 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 RKO98977.1 - 3e-11 43.3 0.0 1.1e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 RKO98977.1 - 1.9e-09 37.2 0.0 0.0031 17.1 0.0 3.3 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO98977.1 - 5.1e-06 26.5 0.0 1.6 8.9 0.0 4.3 4 1 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 RKO98977.1 - 0.00087 19.1 0.0 0.035 14.0 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4523 PF15023.6 RKO98977.1 - 0.0026 17.6 0.0 1.7 8.5 0.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 RKO98977.1 - 0.005 16.9 0.6 2.1 8.4 0.2 3.4 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 RKO98977.1 - 0.035 14.1 0.2 16 5.6 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 RKO98977.1 - 0.056 13.1 3.1 6.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain PRELI PF04707.14 RKO98978.1 - 1.3e-38 132.3 0.0 1.5e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family OTU PF02338.19 RKO98979.1 - 1.1e-11 45.3 0.0 4.4e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 RKO98979.1 - 0.00011 21.8 0.0 0.17 11.3 0.0 2.9 2 1 0 2 2 2 2 Peptidase C65 Otubain Med3 PF11593.8 RKO98979.1 - 5.2 6.2 21.9 0.069 12.3 12.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Nicastrin PF05450.15 RKO98980.1 - 6.5e-24 84.7 0.0 9.7e-17 61.2 0.0 2.7 3 0 0 3 3 3 2 Nicastrin Ncstrn_small PF18266.1 RKO98980.1 - 1.1e-17 64.5 0.0 2.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Nicastrin small lobe Peptidase_M28 PF04389.17 RKO98980.1 - 0.001 18.8 0.6 0.0037 17.0 0.1 2.0 2 0 0 2 2 2 1 Peptidase family M28 TPR_1 PF00515.28 RKO98981.1 - 2.8e-15 55.4 0.8 8e-07 28.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RKO98981.1 - 7.9e-15 53.7 8.6 8.9e-07 28.6 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 RKO98981.1 - 6.8e-14 51.4 10.3 1.5e-07 31.6 0.6 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO98981.1 - 1.8e-13 50.9 18.3 1.2e-06 29.0 1.2 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKO98981.1 - 5.7e-11 41.9 3.0 4.4e-08 32.7 0.3 3.2 3 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 RKO98981.1 - 6e-10 39.5 8.6 5.8e-05 23.5 0.8 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RKO98981.1 - 9.4e-09 35.1 2.4 0.006 16.9 0.1 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO98981.1 - 1.6e-07 30.9 4.3 0.021 14.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKO98981.1 - 2.8e-06 27.1 0.1 0.0039 17.3 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 RKO98981.1 - 3.4e-06 27.3 3.5 0.23 11.8 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO98981.1 - 5.8e-06 26.5 5.1 0.0019 18.5 0.2 4.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO98981.1 - 3.5e-05 24.2 5.8 0.086 13.5 0.0 4.9 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKO98981.1 - 0.00012 21.4 2.4 0.00022 20.6 2.4 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO98981.1 - 0.0036 17.5 2.2 0.75 10.1 0.2 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 RKO98981.1 - 0.0049 16.6 0.0 1.2 8.9 0.0 2.2 1 1 1 2 2 2 2 26S proteasome subunit RPN7 TPR_10 PF13374.6 RKO98981.1 - 0.0079 16.0 0.2 0.0079 16.0 0.2 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKO98981.1 - 0.0087 16.2 9.9 0.93 9.7 0.8 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 RKO98981.1 - 0.27 12.0 0.3 0.27 12.0 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 RKO98981.1 - 0.29 11.0 3.2 2 8.3 0.1 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal BTAD PF03704.17 RKO98981.1 - 0.34 11.3 4.5 0.82 10.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain ADH_zinc_N PF00107.26 RKO98983.1 - 2.5e-16 59.8 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 RKO98983.1 - 0.061 12.7 0.2 0.15 11.4 0.1 1.7 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 RKO98983.1 - 0.15 11.6 0.2 3.6 7.1 0.1 2.4 3 0 0 3 3 3 0 NmrA-like family HGTP_anticodon PF03129.20 RKO98984.1 - 4.7e-19 68.3 0.0 1.1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RKO98984.1 - 1.8e-09 37.8 0.0 4.6e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 RKO98984.1 - 1.2e-05 25.4 9.0 8.6e-05 22.6 7.4 2.4 2 0 0 2 2 2 1 WHEP-TRS domain LRRNT_2 PF08263.12 RKO98984.1 - 0.33 11.3 1.6 24 5.3 0.0 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain SYF2 PF08231.12 RKO98985.1 - 2.8e-11 44.1 3.8 2.8e-11 44.1 1.6 2.2 2 1 0 2 2 2 1 SYF2 splicing factor Tropomyosin_1 PF12718.7 RKO98985.1 - 0.053 13.7 0.9 0.72 10.0 0.2 2.3 2 0 0 2 2 2 0 Tropomyosin like SNF2_N PF00176.23 RKO98986.1 - 1.1e-69 234.8 0.1 1.1e-69 234.8 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO98986.1 - 1.1e-19 70.8 0.0 9.1e-18 64.6 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 RKO98986.1 - 5.5e-19 68.0 0.2 2.1e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Bromodomain SnAC PF14619.6 RKO98986.1 - 1.1e-15 57.9 0.7 8.5e-15 55.1 0.7 2.7 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 RKO98986.1 - 1.3e-09 38.3 0.8 3.4e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit QLQ PF08880.11 RKO98986.1 - 1.6e-08 34.2 0.0 1.6e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 QLQ HSA PF07529.13 RKO98986.1 - 2.6e-07 30.9 8.4 2.6e-07 30.9 8.4 4.1 4 0 0 4 4 4 1 HSA DEAD PF00270.29 RKO98987.1 - 1.1e-15 57.9 0.0 1.4e-09 38.0 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 RKO98987.1 - 0.0058 16.6 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO98987.1 - 0.0096 16.3 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NACHT PF05729.12 RKO98987.1 - 0.021 14.7 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF4267 PF14087.6 RKO98987.1 - 0.14 12.2 1.5 0.53 10.4 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4267) DUF5102 PF17104.5 RKO98988.1 - 1.6e-12 48.1 0.3 9.4e-09 35.7 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF5102) Myosin_tail_1 PF01576.19 RKO98989.1 - 9e-20 70.2 37.7 9.9e-20 70.0 37.7 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 RKO98989.1 - 0.17 11.5 27.2 0.25 10.9 27.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein DASH_Hsk3 PF08227.11 RKO98989.1 - 0.22 11.9 2.2 25 5.3 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Laminin_I PF06008.14 RKO98989.1 - 0.43 10.2 23.8 0.028 14.1 7.5 2.3 1 1 1 2 2 2 0 Laminin Domain I ERM PF00769.19 RKO98989.1 - 0.48 10.2 39.6 0.08 12.8 27.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-H PF05837.12 RKO98989.1 - 0.73 10.3 32.2 0.094 13.1 13.2 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 RKO98989.1 - 0.86 9.8 17.5 0.099 12.8 11.1 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.8 RKO98989.1 - 1.3 7.5 4.9 1.7 7.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.12 RKO98989.1 - 1.4 9.5 6.6 11 6.6 0.6 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.12 RKO98989.1 - 2.8 8.1 12.1 0.82 9.8 2.7 3.2 1 1 2 3 3 3 0 MbeD/MobD like ADIP PF11559.8 RKO98989.1 - 3.1 7.9 34.0 1.4 9.0 14.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1043 PF06295.12 RKO98989.1 - 3.8 7.5 17.7 1.8 8.6 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) FUSC PF04632.12 RKO98989.1 - 4.1 5.8 12.4 4.8 5.6 12.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 RKO98989.1 - 4.3 7.1 31.3 3.4 7.5 18.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 RKO98989.1 - 4.6 7.7 28.9 6.8 7.1 13.0 2.1 1 1 1 2 2 2 0 Fez1 DUF4472 PF14739.6 RKO98989.1 - 4.8 8.0 26.5 0.18 12.5 7.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Prefoldin_2 PF01920.20 RKO98989.1 - 6.2 6.8 32.2 2.1 8.3 1.7 4.3 2 2 2 4 4 4 0 Prefoldin subunit Hemagglutinin PF00509.18 RKO98989.1 - 6.4 5.1 5.6 2.7 6.3 0.2 2.0 1 1 0 2 2 2 0 Haemagglutinin DHR10 PF18595.1 RKO98989.1 - 6.4 6.9 41.1 2.6 8.2 12.0 3.2 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain KxDL PF10241.9 RKO98989.1 - 7.6 6.9 22.0 4.4 7.7 4.0 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 RKO98989.1 - 8.3 6.6 33.6 3.9 7.6 22.7 2.5 1 1 1 2 2 2 0 Tropomyosin like DUF4201 PF13870.6 RKO98989.1 - 8.3 6.1 32.3 18 5.0 8.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF974 PF06159.13 RKO98990.1 - 1.5e-68 231.2 0.0 2.1e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 RKO98990.1 - 0.00012 21.6 0.0 0.004 16.6 0.0 2.7 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 Acyltransferase PF01553.21 RKO98991.1 - 0.0013 18.4 0.0 0.023 14.3 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase SRCR PF00530.18 RKO98991.1 - 0.044 14.3 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain zf-C2H2_3 PF13878.6 RKO98992.1 - 4.4e-13 48.8 0.5 1.5e-12 47.1 0.4 1.8 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Methyltransf_25 PF13649.6 RKO98994.1 - 4.2e-13 49.8 0.0 1.8e-12 47.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO98994.1 - 1.7e-11 44.1 0.0 2.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO98994.1 - 1.8e-11 44.5 0.0 5.2e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RKO98994.1 - 5.5e-11 42.4 0.0 8.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RKO98994.1 - 5.5e-07 29.6 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO98994.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 RKO98994.1 - 9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 RKO98994.1 - 3.5e-05 24.5 0.1 0.00067 20.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 RKO98994.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RKO98994.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 RKO98994.1 - 0.00071 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 RKO98994.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 RKO98994.1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RKO98994.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.19 RKO98994.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 RKO98994.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 RKO98994.1 - 0.048 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 RKO98994.1 - 0.068 14.2 0.4 0.43 11.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 RKO98994.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 RKO98994.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF676 PF05057.14 RKO98995.1 - 2.6e-18 66.3 0.0 2.6e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RKO98995.1 - 0.0031 18.1 0.2 0.0036 17.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 RKO98995.1 - 0.011 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 RKO98995.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.22 RKO98995.1 - 0.068 13.1 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 RKO98995.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 RKO98995.1 - 0.28 10.3 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 RKO98996.1 - 6e-73 245.4 0.0 6.8e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98996.1 - 5.6e-34 117.6 0.0 7.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO98996.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RKO98996.1 - 0.0055 15.7 0.0 0.03 13.3 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKO98996.1 - 0.052 12.9 0.5 0.1 11.9 0.5 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FLILHELTA PF10306.9 RKO98997.1 - 3.7e-10 40.1 0.0 7.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Sensor PF13796.6 RKO98997.1 - 7.7e-05 22.8 0.3 0.00017 21.7 0.3 1.5 1 1 0 1 1 1 1 Putative sensor Fcf1 PF04900.12 RKO98998.1 - 1.8e-34 118.0 1.5 1.8e-34 118.0 1.5 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 RKO98998.1 - 3.4e-07 30.6 0.1 1.3e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 PIN like domain LPMO_10 PF03067.15 RKO98999.1 - 7.7e-07 30.0 0.1 5.9e-06 27.1 0.1 2.2 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ribosomal_L24e PF01246.20 RKO99000.1 - 1.5e-27 95.6 0.2 1.5e-27 95.6 0.2 1.9 3 0 0 3 3 3 1 Ribosomal protein L24e Phosphoesterase PF04185.14 RKO99001.1 - 1.6e-69 234.8 0.4 2e-69 234.5 0.4 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cid2 PF09774.9 RKO99002.1 - 6.3e-21 75.5 1.3 8.4e-21 75.0 1.3 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 SR-25 PF10500.9 RKO99002.1 - 0.00085 19.0 10.2 0.001 18.7 10.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TerB PF05099.13 RKO99002.1 - 0.074 13.0 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TerB Lin-8 PF03353.15 RKO99002.1 - 0.33 10.5 1.0 0.37 10.3 1.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AF-4 PF05110.13 RKO99002.1 - 0.61 8.1 10.8 0.65 8.0 10.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 RKO99002.1 - 1.9 6.7 3.0 2 6.6 3.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.12 RKO99002.1 - 3.6 5.9 7.9 4.2 5.7 7.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ofd1_CTDD PF10637.9 RKO99003.1 - 5.2e-25 88.3 0.0 5.4e-19 68.5 0.0 3.0 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 RKO99003.1 - 6.9e-19 68.3 0.0 2e-17 63.6 0.0 2.7 2 2 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 RKO99003.1 - 8e-15 55.5 0.0 2.7e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sigma70_ner PF04546.13 RKO99003.1 - 0.64 9.9 3.9 34 4.2 4.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RKO99003.1 - 1 7.4 7.3 1.6 6.8 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Response_reg PF00072.24 RKO99004.1 - 9.4e-18 64.4 0.0 3e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain CHASE PF03924.13 RKO99004.1 - 1.3e-11 44.8 0.2 1.3e-10 41.5 0.1 2.6 2 0 0 2 2 2 1 CHASE domain HisKA PF00512.25 RKO99004.1 - 3.3e-05 23.8 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 RKO99004.1 - 0.00042 20.8 0.0 0.086 13.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3377 PF11857.8 RKO99004.1 - 0.00076 19.4 1.3 0.0015 18.4 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) PAS_8 PF13188.7 RKO99004.1 - 0.017 15.1 0.0 0.059 13.4 0.0 1.9 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 RKO99004.1 - 0.032 14.2 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold MutS_V PF00488.21 RKO99007.1 - 2.4e-78 262.5 0.1 5.2e-78 261.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKO99007.1 - 7.9e-30 104.5 0.3 1.9e-29 103.3 0.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 RKO99007.1 - 5.9e-13 49.3 0.0 1.4e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RKO99007.1 - 2.5e-12 47.0 0.0 4.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 RKO99007.1 - 1.5e-08 34.8 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain I hnRNP_Q_AcD PF18360.1 RKO99007.1 - 0.0003 20.7 0.0 0.0011 18.9 0.0 2.0 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain AAA_27 PF13514.6 RKO99007.1 - 0.028 14.0 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain OMPdecase PF00215.24 RKO99008.1 - 3.8e-63 213.1 1.8 2.3e-62 210.5 1.8 1.8 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TFIIA PF03153.13 RKO99009.1 - 0.89 9.5 20.8 0.0075 16.3 7.7 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 RKO99009.1 - 2.1 7.6 26.2 0.033 13.5 9.9 2.2 2 0 0 2 2 2 0 NOA36 protein SDA1 PF05285.12 RKO99009.1 - 2.5 7.5 15.1 0.64 9.4 6.0 2.4 2 0 0 2 2 2 0 SDA1 PCI PF01399.27 RKO99010.1 - 2.5e-10 40.8 0.0 6.6e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 RKO99010.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Rpn9 C-terminal helix TPR_MLP1_2 PF07926.12 RKO99011.1 - 1.2e-17 64.1 28.7 1.2e-17 64.1 28.7 5.0 2 2 3 5 5 5 2 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 RKO99011.1 - 0.00058 18.8 25.7 0.00058 18.8 25.7 3.4 2 2 1 3 3 3 2 Spc7 kinetochore protein Golgin_A5 PF09787.9 RKO99011.1 - 5 6.5 71.5 0.086 12.3 21.0 4.1 1 1 2 4 4 4 0 Golgin subfamily A member 5 Taxilin PF09728.9 RKO99011.1 - 6.4 5.9 56.6 0.046 12.9 2.1 3.6 1 1 1 2 2 2 0 Myosin-like coiled-coil protein adh_short PF00106.25 RKO99012.1 - 1.6e-44 151.7 0.4 3.2e-44 150.7 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO99012.1 - 6.8e-41 140.3 0.4 9.8e-41 139.8 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO99012.1 - 4.4e-10 39.7 0.1 8e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO99012.1 - 4e-05 23.2 0.1 8.6e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RKO99012.1 - 0.021 14.3 0.1 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 RKO99012.1 - 0.078 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding LytR_C PF13399.6 RKO99012.1 - 0.091 13.8 0.3 4.2 8.4 0.0 2.3 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator THF_DHG_CYH_C PF02882.19 RKO99012.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 RKO99012.1 - 0.12 12.4 0.3 0.21 11.6 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TFIIB PF00382.19 RKO99012.1 - 0.14 12.2 0.1 23 5.1 0.0 2.6 3 0 0 3 3 3 0 Transcription factor TFIIB repeat 3HCDH_N PF02737.18 RKO99012.1 - 0.18 11.7 0.3 0.27 11.1 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LSM PF01423.22 RKO99013.1 - 8.3e-13 47.8 0.0 9.6e-13 47.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain LolA_2 PF16584.5 RKO99014.1 - 0.18 11.7 0.3 1.4 8.8 0.1 2.0 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA Pkinase PF00069.25 RKO99015.1 - 7.3e-46 156.7 0.0 1.8e-23 83.3 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99015.1 - 1e-17 64.3 0.0 3.3e-13 49.5 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RKO99015.1 - 4.4e-05 23.5 0.2 0.00033 20.6 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKO99015.1 - 0.00035 19.5 0.0 0.00046 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RasGEF PF00617.19 RKO99017.1 - 4.6e-56 189.8 0.0 6.4e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RKO99017.1 - 7.2e-28 96.9 0.0 3.6e-27 94.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF2070 PF09843.9 RKO99018.1 - 0.061 11.6 1.0 0.094 11.0 1.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Peptidase_U4 PF03419.13 RKO99018.1 - 0.83 8.9 3.0 1.3 8.3 3.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RHD3 PF05879.12 RKO99020.1 - 1.3e-196 655.1 0.1 1.2e-195 651.9 0.1 1.9 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 RKO99020.1 - 8.9e-07 28.4 0.4 2.6e-06 26.9 0.1 1.9 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 RKO99020.1 - 1.4e-05 25.2 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RKO99020.1 - 1.5e-05 25.1 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 RKO99020.1 - 0.011 16.0 1.9 0.031 14.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 RKO99020.1 - 0.14 11.4 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Septin Roc PF08477.13 RKO99020.1 - 0.15 12.2 0.8 0.69 10.1 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2523 PF10734.9 RKO99020.1 - 0.27 11.8 1.8 25 5.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) AAA_16 PF13191.6 RKO99020.1 - 0.94 9.8 6.0 1.7 9.0 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain Proteasome PF00227.26 RKO99021.1 - 5.9e-32 110.7 0.0 7.3e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EAV_GS PF01309.18 RKO99021.1 - 0.095 12.3 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Ribosomal_60s PF00428.19 RKO99022.1 - 8.6e-24 84.0 9.8 1e-23 83.7 9.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RGS PF00615.19 RKO99023.1 - 0.083 13.2 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF1461 PF07314.11 RKO99023.1 - 4.3 7.2 7.7 3.4 7.5 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) PRKCSH_1 PF13015.6 RKO99024.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Spt20 PF12090.8 RKO99024.1 - 0.018 14.7 5.8 0.035 13.7 5.8 1.4 1 0 0 1 1 1 0 Spt20 family PRKCSH PF07915.13 RKO99024.1 - 0.053 14.5 0.0 0.053 14.5 0.0 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein FlxA PF14282.6 RKO99024.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.2 3 0 0 3 3 3 0 FlxA-like protein SUIM_assoc PF16619.5 RKO99024.1 - 0.44 10.6 12.6 2.4 8.3 12.6 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CNDH2_M PF16869.5 RKO99024.1 - 1.4 9.6 21.9 2.9 8.6 11.2 3.9 2 1 0 2 2 2 0 PF16858 RAP1 PF07218.11 RKO99024.1 - 5.2 5.2 4.5 10 4.2 4.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.7 RKO99025.1 - 0.0052 16.6 0.5 0.0098 15.8 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 RKO99025.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 F-box Cwf_Cwc_15 PF04889.12 RKO99025.1 - 0.16 11.7 4.0 0.31 10.7 4.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 RKO99025.1 - 1.5 7.3 3.2 2.4 6.6 3.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HATPase_c_3 PF13589.6 RKO99026.1 - 0.012 15.5 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF563 PF04577.14 RKO99027.1 - 9.1e-19 68.4 0.1 1.5e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Dpy-30 PF05186.13 RKO99028.1 - 3.9e-14 52.1 0.6 3.9e-14 52.1 0.6 2.0 2 0 0 2 2 2 1 Dpy-30 motif ADK PF00406.22 RKO99028.1 - 5.7e-08 33.0 0.0 0.0055 16.8 0.0 3.6 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 RKO99028.1 - 0.00029 21.3 0.1 3.4 8.1 0.0 4.2 4 1 0 4 4 4 2 AAA domain Hydin_ADK PF17213.3 RKO99028.1 - 0.00069 19.9 0.3 0.0046 17.3 0.0 2.1 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Sulphotransf PF09037.10 RKO99028.1 - 0.019 14.5 0.1 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 Stf0 sulphotransferase AAA_22 PF13401.6 RKO99028.1 - 0.021 15.1 0.0 7.6 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain PRONE PF03759.13 RKO99028.1 - 0.052 12.3 0.3 0.097 11.5 0.3 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) AAA PF00004.29 RKO99028.1 - 0.077 13.4 0.2 0.42 11.0 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RKO99028.1 - 0.14 12.3 0.5 1.4 9.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1800 PF08811.11 RKO99028.1 - 0.45 9.5 2.1 1.3 7.9 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1800) Nucleoside_tran PF01733.18 RKO99029.1 - 2.6e-38 132.2 8.0 1.2e-33 116.8 0.5 3.9 3 1 2 5 5 5 2 Nucleoside transporter Zn_clus PF00172.18 RKO99030.1 - 0.022 14.9 8.5 0.04 14.1 8.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SR1P PF13790.6 RKO99030.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 SR1 protein RPEL PF02755.15 RKO99032.1 - 9.5e-19 66.5 24.1 2.9e-05 23.6 3.0 4.5 4 0 0 4 4 4 4 RPEL repeat P16-Arc PF04699.14 RKO99032.1 - 0.0022 18.5 1.6 0.01 16.3 0.2 2.3 1 1 1 2 2 2 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Phage_fiber_2 PF03406.13 RKO99032.1 - 0.49 10.0 2.6 6.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat CBFB_NFYA PF02045.15 RKO99032.1 - 0.98 10.1 4.7 29 5.4 1.8 2.7 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ras PF00071.22 RKO99033.1 - 2.7e-39 134.4 0.0 3.2e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO99033.1 - 1.1e-25 90.1 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO99033.1 - 5.9e-09 35.6 0.0 8.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKO99033.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKO99033.1 - 0.00026 21.0 0.0 0.073 13.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 RKO99033.1 - 0.0024 17.4 0.0 0.0098 15.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 RKO99033.1 - 0.018 14.8 0.0 0.061 13.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain MeaB PF03308.16 RKO99033.1 - 0.042 12.8 0.2 0.41 9.6 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 RKO99033.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 RKO99033.1 - 0.15 12.5 0.1 0.31 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 RKO99034.1 - 1.3e-22 79.6 6.1 6.3e-08 33.2 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99034.1 - 1.7e-07 31.4 0.4 0.68 10.3 0.1 4.5 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 RKO99034.1 - 0.019 15.0 0.6 0.034 14.2 0.6 1.3 1 0 0 1 1 1 0 bZIP transcription factor Ge1_WD40 PF16529.5 RKO99034.1 - 0.031 13.3 0.0 0.18 10.7 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein APC_N_CC PF16689.5 RKO99034.1 - 0.041 13.9 0.6 0.11 12.6 0.6 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Nbas_N PF15492.6 RKO99034.1 - 0.061 12.7 0.1 0.89 8.8 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal HALZ PF02183.18 RKO99034.1 - 0.12 12.6 0.6 0.24 11.7 0.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cyclin PF08613.11 RKO99036.1 - 7.6e-07 29.6 3.3 3.7e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Cyclin Spt20 PF12090.8 RKO99036.1 - 0.035 13.7 34.4 0.056 13.1 34.4 1.2 1 0 0 1 1 1 0 Spt20 family Cyclin_N PF00134.23 RKO99036.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.1 2 0 0 2 2 1 0 Cyclin, N-terminal domain DDHD PF02862.17 RKO99036.1 - 0.079 13.1 3.2 0.15 12.2 3.2 1.4 1 0 0 1 1 1 0 DDHD domain DUF2722 PF10846.8 RKO99036.1 - 0.093 11.7 25.9 0.19 10.7 25.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 RKO99036.1 - 0.18 11.8 34.3 0.29 11.1 26.8 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 RKO99036.1 - 0.39 11.1 7.4 0.77 10.1 7.4 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF913 PF06025.12 RKO99036.1 - 0.41 9.6 2.6 0.69 8.8 2.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FTZ PF03867.14 RKO99036.1 - 0.61 9.6 7.2 2.2 7.7 7.2 2.0 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region PAT1 PF09770.9 RKO99036.1 - 1 7.5 19.4 1.5 7.0 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 RKO99036.1 - 1.1 8.6 9.0 1.7 8.0 9.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 RKO99036.1 - 1.2 8.0 18.4 1.8 7.5 18.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4746 PF15928.5 RKO99036.1 - 1.6 8.1 6.0 2.8 7.3 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GTA_holin_3TM PF11351.8 RKO99036.1 - 1.8 9.2 10.2 3.8 8.1 10.2 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release TERB2 PF15101.6 RKO99036.1 - 2.3 8.2 16.9 3.5 7.6 16.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 RKO99036.1 - 2.6 7.9 14.6 26 4.7 16.1 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) MPM1 PF17234.2 RKO99036.1 - 4.8 7.4 12.7 8.7 6.6 12.7 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4834 PF16118.5 RKO99036.1 - 5.4 8.1 16.7 13 6.9 16.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_18 PF13238.6 RKO99037.1 - 2.7e-13 50.6 0.0 3e-06 27.8 0.0 4.1 4 0 0 4 4 4 2 AAA domain ADK PF00406.22 RKO99037.1 - 2.1e-10 40.9 0.0 0.056 13.5 0.0 3.9 3 0 0 3 3 3 3 Adenylate kinase FAP206 PF12018.8 RKO99037.1 - 6.7e-08 32.4 0.0 0.37 10.2 0.0 3.9 4 0 0 4 4 4 3 Domain of unknown function AAA_17 PF13207.6 RKO99037.1 - 7.9e-07 29.6 0.0 0.73 10.2 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.6 RKO99037.1 - 4.2e-05 23.7 1.6 9.5 6.4 0.0 6.2 5 2 0 5 5 5 1 AAA domain AAA_28 PF13521.6 RKO99037.1 - 0.0036 17.6 0.7 2.2 8.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain YHS PF04945.13 RKO99037.1 - 0.0068 16.5 0.0 4.1 7.6 0.0 2.8 2 0 0 2 2 2 2 YHS domain WD40 PF00400.32 RKO99038.1 - 5.1e-20 71.4 2.4 4.7e-06 27.2 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 RKO99038.1 - 0.00015 20.6 0.0 0.2 10.3 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RKO99038.1 - 0.00024 21.3 0.0 0.28 11.5 0.0 3.1 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 RKO99038.1 - 0.011 15.0 0.1 0.44 9.8 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 RKO99038.1 - 0.018 14.0 0.4 11 4.8 0.0 3.6 1 1 4 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 RKO99038.1 - 0.17 10.9 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain DUF3337 PF11816.8 RKO99040.1 - 6.4e-30 104.3 0.0 9.4e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 RKO99040.1 - 7.1e-18 64.6 8.6 3.2e-06 27.8 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99040.1 - 0.0096 16.2 0.1 1.1 9.5 0.0 3.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Pribosyltran_N PF13793.6 RKO99041.1 - 1.1e-45 154.3 0.6 5.7e-45 152.0 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 RKO99041.1 - 2.3e-43 148.4 2.9 4.5e-38 131.1 0.7 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RKO99041.1 - 1.1e-12 47.8 1.5 3.2e-12 46.3 0.9 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 RKO99041.1 - 0.0013 18.2 0.3 0.0024 17.3 0.3 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 RKO99041.1 - 0.013 15.5 0.2 0.046 13.7 0.4 1.8 2 0 0 2 2 2 0 Chlorosome envelope protein C PAC4 PF16093.5 RKO99041.1 - 0.02 15.1 0.1 0.44 10.8 0.0 2.8 3 0 0 3 3 3 0 Proteasome assembly chaperone 4 TgMIC1 PF11476.8 RKO99041.1 - 0.12 12.2 0.2 0.42 10.3 0.1 1.9 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Totivirus_coat PF05518.11 RKO99042.1 - 0.076 11.1 8.3 0.086 10.9 8.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein Hydrophobin PF01185.18 RKO99043.1 - 1.7e-07 31.8 13.0 2.6e-07 31.2 13.0 1.3 1 0 0 1 1 1 1 Fungal hydrophobin RPA_C PF08784.11 RKO99044.1 - 4.3e-09 37.0 1.1 8.4e-09 36.0 0.2 1.9 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 RKO99044.1 - 2.2e-07 30.7 0.1 9.8e-07 28.7 0.1 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 RKO99044.1 - 0.022 14.6 0.2 0.21 11.4 0.2 2.3 1 1 0 1 1 1 0 RecQ-mediated genome instability protein 2 tRNA_anti_2 PF13742.6 RKO99044.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain WD40 PF00400.32 RKO99045.1 - 8.1e-38 127.8 9.2 5.5e-09 36.5 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99045.1 - 1.7e-10 41.0 0.3 0.12 12.7 0.0 5.4 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO99045.1 - 1.2e-06 27.5 3.1 0.0066 15.2 0.2 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO99045.1 - 4.7e-05 22.5 1.0 1.5 7.7 0.0 4.3 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 RKO99045.1 - 0.00084 18.2 0.0 0.065 12.0 0.0 2.9 2 1 0 2 2 2 1 Nup133 N terminal like PALB2_WD40 PF16756.5 RKO99045.1 - 0.0011 18.0 0.1 0.0045 16.0 0.0 2.0 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 RKO99045.1 - 0.0021 16.5 0.0 0.0034 15.8 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 RKO99045.1 - 0.012 15.4 0.0 4.3 7.0 0.0 3.3 1 1 2 3 3 3 0 TUP1-like enhancer of split Pkinase PF00069.25 RKO99046.1 - 7.5e-69 232.0 0.0 9.7e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99046.1 - 8.5e-42 143.2 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO99046.1 - 2.2e-09 37.1 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO99046.1 - 6.4e-06 26.3 0.5 9.5e-05 22.4 0.5 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKO99046.1 - 0.0021 17.7 0.1 0.003 17.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RKO99046.1 - 0.0021 17.1 0.3 0.0025 16.8 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RKO99046.1 - 0.011 14.5 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RKO99046.1 - 0.013 14.9 0.3 0.11 11.8 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RKO99046.1 - 0.051 13.2 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Iso_dh PF00180.20 RKO99047.1 - 2e-121 405.4 0.0 2.4e-121 405.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribophorin_I PF04597.14 RKO99048.1 - 2e-81 274.4 0.0 2.4e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I VWA_CoxE PF05762.14 RKO99048.1 - 0.0059 16.0 0.1 0.0093 15.4 0.1 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein zf-MYND PF01753.18 RKO99049.1 - 0.00023 21.2 6.8 0.00023 21.2 6.8 2.7 3 0 0 3 3 3 1 MYND finger SET PF00856.28 RKO99049.1 - 0.00032 21.1 0.0 0.001 19.5 0.0 1.9 1 1 0 1 1 1 1 SET domain G10 PF01125.17 RKO99050.1 - 1.9e-63 212.6 1.7 2.1e-63 212.5 1.7 1.0 1 0 0 1 1 1 1 G10 protein ABC_membrane PF00664.23 RKO99051.1 - 2.6e-52 178.2 18.1 3.4e-52 177.8 18.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKO99051.1 - 3.1e-33 115.2 0.0 5.6e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RKO99051.1 - 0.00044 20.7 3.4 0.0036 17.7 0.6 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RKO99051.1 - 0.00079 19.7 0.3 0.051 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 RKO99051.1 - 0.00093 19.1 0.1 3.3 7.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RKO99051.1 - 0.0063 16.3 2.7 0.53 10.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 RKO99051.1 - 0.012 14.5 0.1 0.95 8.2 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 RKO99051.1 - 0.018 14.7 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 RKO99051.1 - 0.02 14.4 0.0 0.74 9.2 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RKO99051.1 - 0.031 14.2 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ABC_membrane_3 PF13748.6 RKO99051.1 - 0.042 13.1 7.3 0.31 10.3 7.3 2.1 1 1 0 1 1 1 0 ABC transporter transmembrane region Rad17 PF03215.15 RKO99051.1 - 0.044 13.7 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 RKO99051.1 - 0.31 10.7 0.0 0.42 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Aminotran_1_2 PF00155.21 RKO99052.1 - 2.6e-79 267.0 0.0 3.6e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RKO99052.1 - 0.00014 20.5 0.0 0.00023 19.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RKO99052.1 - 0.00015 20.8 0.0 0.00027 20.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 RKO99052.1 - 0.0015 19.0 7.8 0.003 18.0 7.8 1.5 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 RKO99052.1 - 0.032 13.5 0.4 0.19 11.0 0.4 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PfkB PF00294.24 RKO99053.1 - 1.6e-68 231.2 0.1 1.9e-68 231.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Mg_trans_NIPA PF05653.14 RKO99055.1 - 2e-17 63.2 9.9 9.4e-09 34.8 0.3 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 RKO99055.1 - 0.0018 18.4 4.3 0.0018 18.4 4.3 3.5 4 0 0 4 4 4 1 EamA-like transporter family DUF5391 PF17369.2 RKO99055.1 - 0.46 10.5 6.1 1.4 9.0 6.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5391) VIT1 PF01988.19 RKO99056.1 - 2.4e-64 217.1 0.0 2.8e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 VIT family 60KD_IMP PF02096.20 RKO99057.1 - 8.5e-30 103.8 0.3 1e-29 103.6 0.3 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_L22 PF00237.19 RKO99058.1 - 0.0017 18.5 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Transket_pyr PF02779.24 RKO99059.1 - 2.3e-59 200.0 0.0 3.7e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RKO99059.1 - 5.8e-45 152.7 0.0 9e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 RKO99059.1 - 7.2e-45 153.2 0.0 1.1e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component zf-GRF PF06839.12 RKO99061.1 - 3.1e-08 33.6 0.7 7.7e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 GRF zinc finger Exo_endo_phos PF03372.23 RKO99062.1 - 3.9e-16 59.3 3.2 9.4e-16 58.0 3.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 RKO99062.1 - 5.1e-05 23.1 0.0 0.19 11.5 0.0 2.5 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase WD40 PF00400.32 RKO99063.1 - 1.1e-22 79.9 0.2 0.0001 23.0 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99063.1 - 5.2e-13 49.1 0.0 0.046 14.0 0.0 5.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKO99063.1 - 6.8e-06 25.8 0.3 1.2e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 PQQ-like domain CSTF1_dimer PF16699.5 RKO99063.1 - 1.7e-05 24.5 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Ge1_WD40 PF16529.5 RKO99063.1 - 0.004 16.2 0.0 4.1 6.3 0.0 3.7 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 RKO99063.1 - 0.0066 15.0 0.0 0.022 13.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain VID27 PF08553.10 RKO99063.1 - 0.0091 15.1 0.1 0.16 11.0 0.0 2.2 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain ACPS PF01648.20 RKO99064.1 - 5.6e-11 42.6 0.0 6.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 RKO99064.1 - 0.0047 17.0 1.8 0.012 15.7 1.8 1.7 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain L51_S25_CI-B8 PF05047.16 RKO99065.1 - 1.1e-08 34.8 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 RKO99065.1 - 0.062 12.6 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain VirE_N PF08800.10 RKO99065.1 - 0.065 13.4 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 VirE N-terminal domain PIH1 PF08190.12 RKO99066.1 - 1.7e-28 99.1 0.0 2.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RKO99066.1 - 2.9e-11 43.6 0.0 8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain tRNA_m1G_MT PF01746.21 RKO99068.1 - 2.9e-17 63.0 0.0 3.4e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF99 PF01949.16 RKO99068.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 AAA_12 PF13087.6 RKO99069.1 - 1.9e-42 145.2 0.0 2.8e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKO99069.1 - 1.8e-22 80.4 0.0 2.2e-14 53.9 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 RKO99069.1 - 1.2e-05 25.7 0.0 2.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO99069.1 - 4.7e-05 23.2 0.1 0.00045 20.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF2439 PF10382.9 RKO99069.1 - 0.00012 22.4 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 RKO99069.1 - 0.00042 20.1 0.3 1.9 8.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 RKO99069.1 - 0.04 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.6 RKO99069.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 RKO99069.1 - 0.074 13.3 0.1 1 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 RKO99069.1 - 0.4 11.3 9.4 1.8 9.2 9.4 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.25 RKO99070.1 - 7.6e-32 110.7 0.0 2.1e-16 60.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Ribonuc_2-5A PF06479.12 RKO99070.1 - 2.7e-17 63.1 0.0 4.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 RKO99070.1 - 2.3e-14 53.3 0.0 8.7e-14 51.4 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 RKO99070.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO99070.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SNARE PF05739.19 RKO99071.1 - 1.4e-05 24.9 0.1 2.9e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 SNARE domain Peptidase_C97 PF05903.14 RKO99072.1 - 0.0087 15.9 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LLC1 PF14945.6 RKO99073.1 - 0.00013 22.5 0.6 0.0021 18.6 0.4 2.0 2 0 0 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF4641 PF15483.6 RKO99073.1 - 0.9 8.6 8.1 1.1 8.3 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) GTP_EFTU PF00009.27 RKO99075.1 - 3.7e-52 176.7 0.0 6.9e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RKO99075.1 - 6.3e-19 67.8 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 RKO99075.1 - 6e-07 29.5 0.1 1.1e-05 25.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 RKO99075.1 - 7.9e-06 26.2 0.1 2.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 FeoB_N PF02421.18 RKO99075.1 - 9e-05 22.0 0.0 0.00093 18.7 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RKO99075.1 - 0.039 13.9 0.1 0.27 11.1 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase SRPRB PF09439.10 RKO99075.1 - 0.05 13.0 0.3 3.5 7.0 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 RKO99075.1 - 0.05 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 RKO99075.1 - 0.091 12.8 0.0 0.78 9.8 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Transket_pyr PF02779.24 RKO99076.1 - 1.8e-45 154.8 0.0 3.6e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RKO99076.1 - 6.5e-40 135.9 0.2 2e-39 134.3 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 RKO99076.1 - 2.9e-05 24.3 0.0 0.0001 22.6 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II adh_short PF00106.25 RKO99077.1 - 1.9e-30 105.8 0.2 6e-30 104.2 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO99077.1 - 1e-16 61.2 1.4 6.8e-16 58.5 1.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 RKO99077.1 - 0.0011 18.9 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RKO99077.1 - 0.0058 16.6 0.8 0.01 15.8 0.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO99077.1 - 0.012 15.0 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RKO99077.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 RKO99077.1 - 0.1 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus AAA_18 PF13238.6 RKO99078.1 - 0.031 14.8 0.0 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKO99078.1 - 0.11 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 RKO99078.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain B12D PF06522.11 RKO99079.1 - 3e-15 55.7 0.1 3.9e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RhoGEF PF00621.20 RKO99080.1 - 5.3e-37 127.8 0.0 7.1e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Velvet PF11754.8 RKO99080.1 - 4.1 7.3 11.4 0.23 11.4 3.3 2.2 2 0 0 2 2 2 0 Velvet factor OPA3 PF07047.12 RKO99081.1 - 5.9e-43 145.6 0.2 7e-43 145.4 0.2 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DivIC PF04977.15 RKO99081.1 - 0.0085 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Septum formation initiator MerR-DNA-bind PF09278.11 RKO99081.1 - 0.087 13.4 0.5 0.18 12.4 0.5 1.5 1 0 0 1 1 1 0 MerR, DNA binding SLT PF01464.20 RKO99081.1 - 0.098 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain DNA_repr_REX1B PF14966.6 RKO99082.1 - 5.7e-08 33.3 0.1 0.00033 21.3 0.0 3.0 3 0 0 3 3 3 2 DNA repair REX1-B PepSY_2 PF13670.6 RKO99082.1 - 6.3 6.9 7.0 2.6 8.1 0.0 3.1 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain NDUF_B7 PF05676.13 RKO99083.1 - 1.3e-24 85.6 8.1 1.8e-24 85.3 8.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 RKO99083.1 - 0.0027 17.7 4.8 0.0035 17.3 4.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 RKO99083.1 - 0.0031 17.6 3.6 0.0051 16.9 3.6 1.4 1 0 0 1 1 1 1 CHCH domain EFhand_Ca_insen PF08726.10 RKO99083.1 - 0.084 13.0 1.3 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand GSH-S_N PF02951.14 RKO99083.1 - 0.11 12.6 0.3 0.14 12.3 0.3 1.1 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain FSA_C PF10479.9 RKO99084.1 - 1.1 7.3 5.6 2.2 6.3 5.6 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RXLR PF16810.5 RKO99084.1 - 5.7 7.4 5.6 16 6.0 5.6 1.7 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity zf-ZPR1 PF03367.13 RKO99085.1 - 8e-110 363.8 0.2 6.3e-55 185.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 RKO99085.1 - 0.0024 17.9 0.5 0.11 12.6 0.1 2.2 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type HypA PF01155.19 RKO99085.1 - 0.0029 17.6 5.9 0.13 12.3 0.2 2.8 2 1 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 RKO99085.1 - 0.074 13.0 8.5 0.43 10.6 1.1 3.3 3 1 0 3 3 3 0 zinc-ribbons zf-ISL3 PF14690.6 RKO99085.1 - 0.096 13.4 5.8 6.7 7.5 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rubredoxin_2 PF18073.1 RKO99085.1 - 1.2 8.9 7.8 7.4 6.4 0.1 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain Lar_restr_allev PF14354.6 RKO99085.1 - 1.4 9.3 6.0 8.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 RKO99085.1 - 6.7 6.3 11.8 2.4 7.7 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 RKO99085.1 - 7.5 6.6 6.6 7.2 6.6 0.1 2.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Aconitase PF00330.20 RKO99086.1 - 4e-151 504.1 0.0 5e-151 503.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RKO99086.1 - 9.4e-46 155.4 0.0 1.6e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain G-patch_2 PF12656.7 RKO99087.1 - 7e-15 54.9 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 G-patch domain KOW PF00467.29 RKO99087.1 - 0.025 14.5 1.0 0.043 13.8 1.0 1.3 1 0 0 1 1 1 0 KOW motif Ribonucleas_3_3 PF14622.6 RKO99089.1 - 4.9e-17 62.3 0.0 7.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 RKO99089.1 - 3e-10 40.7 0.0 1.2e-09 38.7 0.0 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 RKO99089.1 - 3.4e-08 34.0 0.0 6.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain DUF418 PF04235.12 RKO99089.1 - 0.14 12.1 2.1 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF418) DND1_DSRM PF14709.7 RKO99089.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.6 4 0 0 4 4 4 0 double strand RNA binding domain from DEAD END PROTEIN 1 LSM14 PF12701.7 RKO99090.1 - 1.3e-14 54.0 0.0 1.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 RKO99090.1 - 7.9e-14 52.4 0.2 3.7e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 RKO99090.1 - 0.00095 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 RKO99090.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 LSM domain Mur_ligase_M PF08245.12 RKO99091.1 - 1.7e-05 24.9 0.5 0.00083 19.4 0.5 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Bax1-I PF01027.20 RKO99092.1 - 1.2e-25 90.6 9.8 1.5e-25 90.2 9.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 zf-NF-X1 PF01422.17 RKO99093.1 - 0.00018 21.4 38.3 0.0022 18.0 16.3 16.8 19 2 2 21 21 21 6 NF-X1 type zinc finger zf-RING_11 PF17123.5 RKO99093.1 - 0.00027 20.6 4.5 0.00027 20.6 4.5 6.4 6 0 0 6 6 6 1 RING-like zinc finger tRNA-synt_1c PF00749.21 RKO99094.1 - 7.8e-109 363.4 0.0 1.1e-108 362.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 RKO99094.1 - 4.9e-40 137.2 0.0 8.8e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 RKO99094.1 - 8.9e-33 113.6 0.0 4.7e-32 111.2 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 RKO99094.1 - 3.6e-11 43.8 0.2 6.9e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SOG2 PF10428.9 RKO99095.1 - 0.32 10.1 28.8 4.1 6.5 26.5 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Pyr_redox_2 PF07992.14 RKO99096.1 - 1.4e-64 218.2 6.8 1.4e-64 218.2 6.8 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RKO99096.1 - 2.5e-40 137.2 0.1 7.7e-40 135.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RKO99096.1 - 1.2e-20 73.8 11.8 1.4e-18 67.2 1.2 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RKO99096.1 - 8.3e-11 41.9 0.8 8.3e-11 41.9 0.8 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 RKO99096.1 - 1.6e-08 34.1 4.9 1.6e-08 34.1 4.9 2.8 2 2 1 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 RKO99096.1 - 2e-07 30.6 7.8 4.1e-05 23.0 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RKO99096.1 - 2.9e-07 30.6 2.6 0.00028 21.0 0.5 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 RKO99096.1 - 6.2e-06 25.6 2.6 6.2e-06 25.6 2.6 3.8 4 0 0 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 RKO99096.1 - 6.9e-05 22.2 8.1 0.0025 17.1 0.2 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 RKO99096.1 - 8.8e-05 21.9 11.5 0.043 13.1 1.0 4.2 4 1 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 RKO99096.1 - 0.00021 20.1 14.4 0.00069 18.4 1.2 4.0 3 1 1 4 4 4 2 HI0933-like protein Thi4 PF01946.17 RKO99096.1 - 0.00031 20.1 0.2 0.00031 20.1 0.2 2.4 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 RKO99096.1 - 0.0072 15.5 3.8 0.066 12.3 0.1 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF531 PF04407.12 RKO99096.1 - 0.14 12.3 0.6 0.52 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF531) NAD_binding_7 PF13241.6 RKO99096.1 - 0.59 10.6 3.5 9.7 6.7 0.1 3.4 3 0 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 RKO99096.1 - 2.2 7.2 6.9 0.87 8.6 0.9 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein PP2C PF00481.21 RKO99098.1 - 1.2e-17 64.5 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 RKO99098.1 - 0.083 12.5 0.1 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein phosphatase 2C TPR_1 PF00515.28 RKO99099.1 - 5.7e-48 158.9 17.2 4e-09 35.9 0.1 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99099.1 - 2e-45 149.2 18.7 1.4e-06 28.0 0.1 10.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 RKO99099.1 - 1.3e-30 105.7 19.1 4.7e-08 33.4 0.0 6.7 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99099.1 - 2.7e-30 104.7 13.0 4.6e-09 36.8 0.0 6.7 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99099.1 - 2.8e-29 101.2 27.2 7.6e-07 29.3 0.3 8.6 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99099.1 - 6.1e-27 93.0 12.1 2.7e-05 23.8 0.0 7.1 5 1 1 6 6 6 5 TPR repeat TPR_8 PF13181.6 RKO99099.1 - 8.4e-25 84.9 11.8 0.00042 20.3 0.0 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 RKO99099.1 - 3.6e-23 80.3 25.7 0.0095 16.7 0.0 10.6 2 2 9 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99099.1 - 1.9e-22 77.6 12.2 0.00029 20.7 0.0 8.9 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99099.1 - 3.7e-21 73.9 17.6 0.00029 21.0 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 RKO99099.1 - 3.2e-15 55.4 21.8 0.0013 18.5 0.1 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99099.1 - 5.4e-14 51.8 22.5 0.079 13.6 0.1 9.3 9 1 0 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO99099.1 - 1.1e-13 51.3 16.2 8.3e-05 22.7 0.8 6.1 3 2 5 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RKO99099.1 - 1.9e-07 31.1 22.3 0.005 17.0 0.2 5.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 RKO99099.1 - 2.2e-06 27.5 14.2 0.0021 17.8 1.3 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat-like domain RPN7 PF10602.9 RKO99099.1 - 1.4e-05 24.9 5.1 0.026 14.3 0.2 3.6 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_15 PF13429.6 RKO99099.1 - 3.8e-05 23.0 16.7 0.034 13.3 0.2 4.3 1 1 1 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 RKO99099.1 - 4.8e-05 22.9 3.4 0.18 11.2 0.0 3.6 2 1 3 5 5 5 2 Coatomer epsilon subunit TPR_4 PF07721.14 RKO99099.1 - 0.0013 19.1 10.6 2.4 9.0 0.0 7.4 8 0 0 8 8 5 1 Tetratricopeptide repeat PPR PF01535.20 RKO99099.1 - 0.0014 18.7 2.8 24 5.5 0.0 6.1 8 0 0 8 8 6 0 PPR repeat TPR_20 PF14561.6 RKO99099.1 - 0.0017 18.6 4.4 1.3 9.4 0.0 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.6 RKO99099.1 - 0.0029 17.7 0.4 13 6.1 0.0 5.1 5 0 0 5 5 5 0 PPR repeat family NARP1 PF12569.8 RKO99099.1 - 0.014 14.3 0.8 0.014 14.3 0.8 2.6 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 RKO99099.1 - 0.072 13.2 4.7 6 6.9 0.1 4.5 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 RKO99099.1 - 0.09 12.9 10.6 14 5.8 0.1 5.7 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 RKO99099.1 - 0.091 12.8 14.5 0.096 12.7 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RKO99099.1 - 1.1 9.8 4.1 8.7 6.8 0.0 3.3 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation Sec1 PF00995.23 RKO99100.1 - 3.2e-105 353.5 0.0 3.6e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Kinesin_assoc PF16183.5 RKO99100.1 - 0.045 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinesin-associated SPDY PF03771.16 RKO99100.1 - 0.07 13.1 0.0 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Pkinase PF00069.25 RKO99101.1 - 5.1e-65 219.5 0.0 9.2e-59 198.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99101.1 - 2.7e-35 121.9 0.1 5.3e-33 114.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO99101.1 - 1.2e-08 34.6 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO99101.1 - 8.1e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKO99101.1 - 0.00025 20.1 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKO99101.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKO99101.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family EF-hand_1 PF00036.32 RKO99102.1 - 4.8e-26 88.3 3.0 9.1e-06 24.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKO99102.1 - 3.1e-23 82.0 1.4 7.5e-12 45.5 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RKO99102.1 - 1.2e-20 71.5 2.1 7.1e-05 22.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RKO99102.1 - 4.3e-19 67.1 2.7 5.4e-06 25.7 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RKO99102.1 - 8.4e-15 54.4 6.4 0.009 15.8 0.0 4.5 3 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RKO99102.1 - 9.8e-08 32.3 0.0 0.0023 18.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Anthrax-tox_M PF09156.10 RKO99102.1 - 0.00034 20.1 0.1 0.055 12.8 0.0 2.1 2 0 0 2 2 2 2 Anthrax toxin lethal factor, middle domain EF-hand_9 PF14658.6 RKO99102.1 - 0.0032 17.8 0.1 0.42 11.0 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain Sigma54_CBD PF04963.13 RKO99102.1 - 0.0064 16.4 0.1 0.12 12.3 0.0 2.2 1 1 0 2 2 2 1 Sigma-54 factor, core binding domain Rab5ip PF07019.12 RKO99103.1 - 4.1e-15 56.1 3.8 5.1e-15 55.8 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PH PF00169.29 RKO99104.1 - 0.0068 16.9 0.0 2.8 8.5 0.0 2.4 2 0 0 2 2 2 2 PH domain DUF5098 PF17023.5 RKO99104.1 - 0.049 12.6 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) Oxysterol_BP PF01237.18 RKO99105.1 - 1.3e-75 254.6 0.0 1e-69 235.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Mre11_DNA_bind PF04152.14 RKO99107.1 - 7.2e-41 140.3 0.0 1.1e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 RKO99107.1 - 1.3e-13 51.9 2.1 3e-13 50.7 2.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RKO99107.1 - 5.2e-06 26.8 0.7 6.3e-05 23.2 0.7 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Crp PF00325.20 RKO99107.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Ribosomal_L2_C PF03947.18 RKO99108.1 - 1.5e-42 144.8 1.6 1.5e-42 144.8 1.6 2.6 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RKO99108.1 - 8.5e-18 64.1 0.2 8.5e-18 64.1 0.2 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PH PF00169.29 RKO99109.1 - 5e-07 30.2 0.0 8.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 PH domain Cnd2 PF05786.14 RKO99109.1 - 0.13 10.9 9.8 0.16 10.6 9.8 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 CDC45 PF02724.14 RKO99109.1 - 0.16 10.2 21.0 0.24 9.7 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 RKO99109.1 - 0.75 9.6 6.0 1.2 9.0 6.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.6 RKO99109.1 - 1.2 9.6 24.3 1.6 9.2 16.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.12 RKO99109.1 - 1.3 8.4 17.8 1.7 8.0 17.8 1.1 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 RKO99109.1 - 2.4 6.5 16.4 3.3 6.1 16.4 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 RKO99109.1 - 3.8 5.6 17.6 5 5.2 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RKO99109.1 - 4 6.7 22.5 5.2 6.3 22.5 1.2 1 0 0 1 1 1 0 BUD22 Mito_carr PF00153.27 RKO99110.1 - 2e-66 220.0 7.4 2.4e-24 85.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4684 PF15736.5 RKO99110.1 - 0.07 11.8 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Fuseless PF15993.5 RKO99110.1 - 0.096 11.9 0.1 0.26 10.5 0.1 1.6 2 0 0 2 2 2 0 Fuseless Sacchrp_dh_C PF16653.5 RKO99111.1 - 7.4e-78 262.3 0.0 1.3e-77 261.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 RKO99111.1 - 2e-24 86.5 0.0 3.4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 RKO99111.1 - 1.3e-14 54.5 0.1 1.5e-13 51.1 0.2 2.5 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 RKO99111.1 - 0.00061 19.1 0.0 0.02 14.2 0.0 2.7 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TFIIIC_delta PF12657.7 RKO99113.1 - 2.7e-06 27.4 0.1 1.7e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term SDA1 PF05285.12 RKO99113.1 - 1.4 8.3 5.4 2.3 7.6 5.4 1.2 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 RKO99114.1 - 3.4e-37 125.8 22.9 3.9e-08 33.8 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 RKO99114.1 - 2e-12 46.8 0.5 5.2e-12 45.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 RKO99114.1 - 6.5e-08 31.7 8.3 0.015 14.0 0.2 4.3 2 1 3 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.33 RKO99114.1 - 2.7e-06 27.1 0.1 5.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 RKO99114.1 - 6.1e-05 23.2 0.7 3 8.2 0.0 4.5 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 RKO99114.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box DUF2076 PF09849.9 RKO99115.1 - 0.005 16.9 8.2 0.0094 16.0 8.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF4407 PF14362.6 RKO99115.1 - 0.092 12.1 9.9 0.15 11.4 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RIFIN PF02009.16 RKO99115.1 - 0.13 12.1 3.4 0.28 11.1 3.4 1.4 1 0 0 1 1 1 0 Rifin MOFRL PF05161.13 RKO99116.1 - 0.82 9.9 3.6 1 9.6 2.1 1.9 1 1 0 2 2 2 0 MOFRL family KCH PF16944.5 RKO99117.1 - 1.3e-53 182.4 11.1 1.7e-53 182.0 11.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel RTX PF02382.15 RKO99117.1 - 0.001 18.9 1.2 0.0017 18.1 1.2 1.3 1 0 0 1 1 1 1 N-terminal domain in RTX protein Cation_ATPase_C PF00689.21 RKO99118.1 - 3.9e-08 33.2 5.2 6.7e-08 32.5 5.2 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RKO99118.1 - 0.0017 17.9 0.2 0.0017 17.9 0.2 3.2 5 0 0 5 5 5 1 E1-E2 ATPase EF_assoc_2 PF08356.12 RKO99119.1 - 6.1e-30 103.1 0.0 2e-29 101.4 0.0 1.9 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 RKO99119.1 - 1.6e-25 89.5 0.0 9.2e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 RKO99119.1 - 1.2e-18 66.4 0.3 2.2e-18 65.6 0.3 1.4 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 RKO99119.1 - 1.1e-16 61.2 0.0 4.4e-10 39.8 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RKO99119.1 - 2.5e-10 40.4 0.0 0.00037 20.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 RKO99119.1 - 5.7e-10 38.9 0.0 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.6 RKO99119.1 - 7.5e-08 31.7 3.1 0.0043 16.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 RKO99119.1 - 2.3e-07 29.9 2.3 0.0095 15.4 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 RKO99119.1 - 2e-06 28.1 0.0 0.021 15.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.6 RKO99119.1 - 5.5e-06 26.9 0.1 0.031 14.6 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain EF-hand_10 PF14788.6 RKO99119.1 - 4.8e-05 23.1 0.7 0.014 15.3 0.0 2.6 2 0 0 2 2 2 1 EF hand Septin PF00735.18 RKO99119.1 - 4.9e-05 22.7 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 2 Septin FtsK_SpoIIIE PF01580.18 RKO99119.1 - 0.00016 21.2 0.0 0.029 13.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family SRPRB PF09439.10 RKO99119.1 - 0.00034 20.1 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RKO99119.1 - 0.00064 19.3 0.1 3 7.3 0.0 3.6 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RKO99119.1 - 0.00072 19.8 0.0 0.96 9.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.9 RKO99119.1 - 0.00084 19.1 0.1 1.9 8.2 0.1 3.5 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation EF-hand_8 PF13833.6 RKO99119.1 - 0.00089 19.1 0.3 2.4 8.1 0.1 2.8 3 0 0 3 3 2 2 EF-hand domain pair AAA_29 PF13555.6 RKO99119.1 - 0.0013 18.4 0.7 2 8.2 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain EF-hand_5 PF13202.6 RKO99119.1 - 0.0028 17.1 3.5 0.082 12.4 0.2 2.5 2 0 0 2 2 2 1 EF hand RsgA_GTPase PF03193.16 RKO99119.1 - 0.0032 17.4 0.0 12 5.7 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase NACHT PF05729.12 RKO99119.1 - 0.0035 17.3 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 RKO99119.1 - 0.0053 16.3 0.0 0.8 9.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 RKO99119.1 - 0.0068 16.9 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 RKO99119.1 - 0.012 15.9 0.0 0.57 10.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain MCM PF00493.23 RKO99119.1 - 0.021 13.9 0.1 9.8 5.2 0.0 3.3 4 0 0 4 4 4 0 MCM P-loop domain DUF815 PF05673.13 RKO99119.1 - 0.022 13.9 0.0 6.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 RKO99119.1 - 0.025 14.0 0.0 2.5 7.5 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein AAA_33 PF13671.6 RKO99119.1 - 0.026 14.7 0.4 3.9 7.6 0.1 3.1 2 2 0 3 3 2 0 AAA domain AAA_25 PF13481.6 RKO99119.1 - 0.027 14.1 0.1 3.2 7.3 0.0 3.0 3 1 1 4 4 4 0 AAA domain TsaE PF02367.17 RKO99119.1 - 0.042 13.8 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 RKO99119.1 - 0.047 13.7 0.1 12 6.0 0.0 2.9 2 2 2 4 4 4 0 Dynamin family RNA_helicase PF00910.22 RKO99119.1 - 0.11 12.9 0.0 10 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 RKO99119.1 - 0.13 11.4 0.0 0.74 8.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 RKO99119.1 - 0.14 11.7 0.3 1.9 8.1 0.1 2.7 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 RKO99119.1 - 0.2 10.7 0.0 0.55 9.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2362 PF10154.9 RKO99120.1 - 6.6e-24 84.7 0.0 3.5e-23 82.3 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2362) SR-25 PF10500.9 RKO99120.1 - 7 6.2 6.4 14 5.2 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.6 RKO99121.1 - 3.9 7.9 7.0 8.1 6.9 7.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arf PF00025.21 RKO99122.1 - 3.8e-78 260.9 0.1 4.4e-78 260.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RKO99122.1 - 4.6e-17 62.1 0.0 5.3e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO99122.1 - 1.1e-16 61.1 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RKO99122.1 - 7.7e-13 48.3 0.2 2.9e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RKO99122.1 - 1e-12 47.9 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKO99122.1 - 7.9e-10 38.5 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO99122.1 - 3.6e-06 27.1 0.0 5.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 RKO99122.1 - 3.9e-05 22.8 0.2 0.021 13.8 0.1 3.0 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 RKO99122.1 - 0.00025 21.0 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 RKO99122.1 - 0.0011 18.6 0.3 0.25 10.9 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 RKO99122.1 - 0.0018 17.8 0.1 0.017 14.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 RKO99122.1 - 0.0047 17.5 0.0 0.0078 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain NOG1 PF06858.14 RKO99122.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) ABC_tran PF00005.27 RKO99122.1 - 0.062 13.8 0.4 0.12 12.9 0.4 1.7 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 RKO99122.1 - 0.092 12.4 0.2 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 RKO99122.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RKO99122.1 - 0.22 11.8 0.8 1.4 9.2 0.5 2.3 1 1 1 2 2 2 0 AAA domain Cyclin PF08613.11 RKO99123.1 - 0.0059 17.0 0.1 0.021 15.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin PMM PF03332.13 RKO99124.1 - 5e-104 346.9 0.2 5.7e-104 346.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 RKO99124.1 - 0.00039 20.2 0.0 0.056 13.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 RKO99124.1 - 0.1 12.1 0.0 5.4 6.5 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 RKO99124.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase HAD PF12710.7 RKO99124.1 - 0.28 11.6 0.9 3 8.2 0.0 2.6 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 RKO99125.1 - 9.5e-21 74.1 13.2 6.3e-05 23.4 0.1 6.5 6 1 1 7 7 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO99125.1 - 3.4e-14 52.8 20.0 0.00016 21.8 1.2 5.6 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RKO99125.1 - 2.1e-10 40.5 8.9 0.069 13.8 0.1 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO99125.1 - 1.2e-08 35.1 7.8 0.0035 18.1 0.1 8.2 6 3 3 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99125.1 - 2.3e-08 33.5 25.2 0.0024 17.9 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99125.1 - 1.9e-07 31.6 8.6 0.036 14.7 0.1 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99125.1 - 1.3e-06 28.6 15.8 0.9 9.9 0.3 8.0 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99125.1 - 5e-06 26.2 8.5 0.64 10.2 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99125.1 - 1.3e-05 25.0 4.9 1.4 9.3 0.0 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKO99125.1 - 1.9e-05 24.7 2.7 3.1 8.0 0.0 5.5 5 2 1 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 RKO99125.1 - 0.00013 21.5 5.5 0.13 11.6 0.2 3.6 3 1 1 4 4 4 2 Coatomer epsilon subunit TPR_4 PF07721.14 RKO99125.1 - 0.00035 20.9 0.1 26 5.8 0.0 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99125.1 - 0.00037 20.7 3.4 12 6.5 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RKO99125.1 - 0.004 16.8 0.5 14 5.4 0.0 3.8 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 RKO99125.1 - 0.018 14.9 3.1 9.9 6.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 RKO99125.1 - 0.32 11.4 7.4 36 4.9 0.0 5.7 7 0 0 7 7 7 0 PPR repeat TPR_1 PF00515.28 RKO99125.1 - 0.35 10.8 29.6 1.1 9.2 0.1 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 RKO99125.1 - 4.6 7.3 14.5 4.9 7.3 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Topoisom_bac PF01131.20 RKO99126.1 - 3.2e-100 336.0 0.0 3.9e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 RKO99126.1 - 8.1e-20 71.0 0.0 2.2e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Toprim domain TPT PF03151.16 RKO99127.1 - 4.1e-45 154.4 27.4 4.8e-45 154.1 27.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 RKO99127.1 - 1.3e-06 27.9 26.3 3e-06 26.7 26.3 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 RKO99127.1 - 3.1e-06 27.4 37.8 0.0031 17.7 15.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Na_H_Exchanger PF00999.21 RKO99128.1 - 9.3e-56 189.2 42.0 1.2e-55 188.9 42.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 RKO99129.1 - 1.2e-50 172.4 43.2 1.5e-50 172.1 43.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family A_deamin PF02137.18 RKO99131.1 - 9.2e-47 160.1 0.0 1.5e-45 156.1 0.0 2.2 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain K_channel_TID PF07941.11 RKO99131.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.6 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain SR-25 PF10500.9 RKO99132.1 - 0.0023 17.6 13.9 0.0051 16.4 13.9 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 RKO99132.1 - 0.15 11.7 1.1 0.24 11.1 1.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 RKO99132.1 - 0.95 7.9 1.4 1.4 7.4 1.4 1.1 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 RKO99132.1 - 1.5 6.5 3.8 2.1 6.0 3.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CCDC106 PF15794.5 RKO99132.1 - 9.9 5.8 6.8 22 4.6 6.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Gar1 PF04410.14 RKO99133.1 - 3.5e-25 88.6 2.0 5e-12 45.9 0.0 2.6 3 0 0 3 3 3 2 Gar1/Naf1 RNA binding region CBS PF00571.28 RKO99135.1 - 1.8e-16 60.3 0.0 1e-08 35.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain DEAD PF00270.29 RKO99136.1 - 2.3e-24 86.1 0.0 4.6e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO99136.1 - 5.5e-11 42.8 0.1 1.6e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO99136.1 - 3.8e-05 23.8 0.0 5.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Bromodomain PF00439.25 RKO99137.1 - 8.5e-15 54.6 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Ank_2 PF12796.7 RKO99137.1 - 2.8e-07 31.0 0.0 5.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKO99137.1 - 1e-06 28.9 0.0 0.017 15.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RKO99137.1 - 2.8e-06 27.5 0.3 0.0015 18.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RKO99137.1 - 0.00032 20.9 0.0 1.4 9.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 RKO99137.1 - 0.00071 20.1 0.2 0.0089 16.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) tRNA-synt_1b PF00579.25 RKO99138.1 - 6.7e-20 71.6 0.0 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) TFIIIC_sub6 PF10419.9 RKO99139.1 - 0.0011 18.8 0.0 0.0036 17.1 0.0 1.8 2 0 0 2 2 2 1 TFIIIC subunit triple barrel domain Vps55 PF04133.14 RKO99140.1 - 8.8e-38 128.9 6.4 1e-37 128.7 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Herpes_LMP1 PF05297.11 RKO99140.1 - 0.36 10.0 3.2 0.63 9.2 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) p450 PF00067.22 RKO99141.1 - 1.1e-71 242.1 0.0 1.6e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Nup84_Nup100 PF04121.13 RKO99141.1 - 0.3 9.1 0.0 0.41 8.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 Sda PF08970.10 RKO99142.1 - 0.01 15.5 9.3 2.1 8.2 0.0 5.2 6 0 0 6 6 6 0 Sporulation inhibitor A SpoIIIAH PF12685.7 RKO99142.1 - 3.9 7.3 10.3 0.37 10.6 3.3 2.6 2 0 0 2 2 2 0 SpoIIIAH-like protein RGS PF00615.19 RKO99143.1 - 0.019 15.3 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain PHD PF00628.29 RKO99144.1 - 2e-08 34.0 4.6 2e-08 34.0 4.6 2.9 4 0 0 4 4 4 1 PHD-finger zf-CpG_bind_C PF12269.8 RKO99144.1 - 0.0083 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain RGS PF00615.19 RKO99145.1 - 0.00057 20.1 0.3 0.0011 19.2 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain GDP_Man_Dehyd PF16363.5 RKO99146.1 - 5.5e-67 226.5 0.0 6.4e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RKO99146.1 - 7.7e-61 205.6 0.1 9.5e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RKO99146.1 - 3.5e-24 85.4 0.0 5.3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RKO99146.1 - 2.1e-20 72.9 0.0 2.6e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RKO99146.1 - 1.3e-19 70.4 0.6 4.7e-18 65.3 0.6 2.7 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 RKO99146.1 - 3.2e-18 65.8 0.0 6.4e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RKO99146.1 - 6.4e-07 29.4 0.0 1.6e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 RKO99146.1 - 0.00038 20.0 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase DKCLD PF08068.12 RKO99146.1 - 0.12 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 DKCLD (NUC011) domain F-box-like PF12937.7 RKO99147.1 - 2.4e-06 27.3 0.1 2.4e-06 27.3 0.1 3.2 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 RKO99147.1 - 0.025 14.4 0.0 0.18 11.6 0.0 2.0 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 RKO99147.1 - 0.13 12.7 0.0 2.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Il2rg PF15874.5 RKO99148.1 - 1.4e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain CPSase_sm_chain PF00988.22 RKO99149.1 - 2.5e-43 147.0 0.0 3.8e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 RKO99149.1 - 5e-37 127.5 0.0 7.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKO99149.1 - 3.5e-05 23.7 1.6 0.0021 17.8 1.6 2.9 1 1 0 1 1 1 1 Peptidase C26 ThiF PF00899.21 RKO99150.1 - 4.3e-39 134.3 0.0 6.5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 RKO99150.1 - 0.00012 22.5 0.0 0.00034 21.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 RKO99150.1 - 0.016 15.5 0.1 5.3 7.3 0.2 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thioredoxin PF00085.20 RKO99151.1 - 1e-35 121.8 0.0 3.8e-21 75.0 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 RKO99151.1 - 9.7e-09 35.4 0.0 0.00028 20.8 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RKO99151.1 - 1.1e-07 31.9 3.1 0.0043 17.2 0.1 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 RKO99151.1 - 7.6e-06 26.2 0.0 0.12 12.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO99151.1 - 0.0023 18.4 0.2 0.69 10.4 0.0 3.3 3 1 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 RKO99151.1 - 0.0052 16.7 0.1 3.7 7.5 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 RKO99151.1 - 0.024 14.4 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin zf-FPG_IleRS PF06827.14 RKO99151.1 - 0.8 9.6 4.0 14 5.6 0.6 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Amidohydro_1 PF01979.20 RKO99152.1 - 9.7e-59 199.4 0.0 5.8e-58 196.9 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 RKO99152.1 - 5.1e-11 42.7 1.8 1.4e-07 31.3 0.6 2.8 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 RKO99152.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Aminotran_1_2 PF00155.21 RKO99153.1 - 1.2e-42 146.4 0.0 1.4e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Sel1 PF08238.12 RKO99154.1 - 3.6e-17 62.4 11.9 2e-07 31.4 0.9 3.2 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 RKO99154.1 - 0.54 11.0 9.3 11 7.0 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyoxal_oxid_N PF07250.11 RKO99155.1 - 5e-20 71.7 0.0 3.4e-19 69.0 0.0 2.2 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 RKO99155.1 - 1.3e-15 57.5 0.2 3.1e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) RCC1_2 PF13540.6 RKO99155.1 - 0.062 13.1 0.5 1.8 8.4 0.1 3.2 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 RKO99155.1 - 0.15 12.1 0.3 4 7.6 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Hist_deacetyl PF00850.19 RKO99156.1 - 4.5e-84 282.5 0.0 6.2e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Skp1_POZ PF03931.15 RKO99157.1 - 1.7e-09 37.7 0.0 2.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 RKO99157.1 - 0.0068 16.6 0.2 0.0083 16.3 0.2 1.3 1 1 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 RKO99158.1 - 7.6e-38 127.8 7.4 2.2e-06 28.3 0.3 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99158.1 - 1.7e-20 73.1 0.0 0.00032 21.0 0.0 6.0 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 RKO99158.1 - 1.8e-08 34.1 0.3 1.8e-08 34.1 0.3 1.9 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 RKO99158.1 - 1.1e-05 25.3 0.0 0.63 9.9 0.0 4.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RKO99158.1 - 2.5e-05 23.4 2.7 1.2 8.0 0.0 4.4 4 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKO99158.1 - 0.049 12.3 0.5 26 3.3 0.0 3.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 V_ATPase_I PF01496.19 RKO99159.1 - 2 6.2 6.6 2.4 6.0 4.8 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MIP PF00230.20 RKO99160.1 - 3.8e-47 160.9 15.1 4.9e-47 160.5 15.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF962 PF06127.11 RKO99160.1 - 6.7 6.9 6.6 91 3.2 4.6 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF962) Glutaredoxin PF00462.24 RKO99161.1 - 1.1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin ATP-synt_C PF00137.21 RKO99162.1 - 1.4e-27 95.8 31.5 2.2e-16 60.0 7.2 2.6 3 0 0 3 3 3 2 ATP synthase subunit C RhoGEF PF00621.20 RKO99163.1 - 1.5e-25 90.5 0.0 2.8e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 RKO99163.1 - 9.5e-09 35.0 0.2 2.4e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKO99163.1 - 3e-07 30.0 0.0 6.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO99163.1 - 7.1e-07 28.7 0.9 1.2e-06 28.0 0.2 1.9 2 0 0 2 2 2 1 SH3 domain BAR PF03114.18 RKO99163.1 - 3.4e-06 26.9 3.9 0.00075 19.2 1.0 2.4 2 0 0 2 2 2 2 BAR domain Pkinase PF00069.25 RKO99164.1 - 1.7e-51 175.1 0.0 1.9e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99164.1 - 2.9e-24 85.8 0.0 3.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO99164.1 - 1.4e-07 31.1 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO99164.1 - 0.00057 19.9 0.6 0.0064 16.4 0.2 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RKO99164.1 - 0.01 15.2 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Branch PF02485.21 RKO99165.1 - 0.0025 17.4 0.2 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 Core-2/I-Branching enzyme DUF1690 PF07956.11 RKO99165.1 - 5.1 7.5 6.9 1 9.8 0.2 2.7 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) DEAD PF00270.29 RKO99167.1 - 1.9e-45 154.8 0.8 1.1e-44 152.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO99167.1 - 8.7e-25 87.2 0.0 1.4e-23 83.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 RKO99167.1 - 9.8e-11 41.8 0.3 9.8e-11 41.8 0.3 2.3 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.15 RKO99167.1 - 3.3e-08 33.7 0.0 8.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKO99167.1 - 2.2e-05 23.8 0.0 5.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ThiF PF00899.21 RKO99168.1 - 1.3e-60 204.8 0.0 1.8e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 RKO99168.1 - 1.4e-22 79.6 0.0 2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 RKO99168.1 - 0.036 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 RKO99168.1 - 0.095 12.9 1.7 0.27 11.4 1.7 1.8 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein LUC7 PF03194.15 RKO99169.1 - 3.4e-50 171.1 0.0 5.8e-50 170.3 0.0 1.4 1 1 0 1 1 1 1 LUC7 N_terminus AvrM_N PF18247.1 RKO99169.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain PUF PF00806.19 RKO99170.1 - 2.6e-17 61.5 0.0 0.11 12.2 0.0 7.6 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Mt_ATP-synt_D PF05873.12 RKO99171.1 - 3.3e-22 79.0 1.7 4.1e-22 78.7 1.7 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.9 RKO99171.1 - 0.22 12.1 1.0 0.42 11.2 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TMPIT PF07851.13 RKO99171.1 - 0.26 10.5 0.8 0.32 10.2 0.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Vac_ImportDeg PF09783.9 RKO99172.1 - 1e-46 158.7 0.2 1.1e-46 158.5 0.2 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Exo_endo_phos PF03372.23 RKO99173.1 - 1.5e-08 34.5 0.1 3e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ANAPC4_WD40 PF12894.7 RKO99173.1 - 0.018 15.3 0.0 0.28 11.5 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 RKO99174.1 - 1e-09 38.2 0.3 3.1e-09 36.7 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 RKO99174.1 - 1.6e-07 31.7 0.4 5.1e-07 30.0 0.4 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 RKO99174.1 - 0.00012 22.1 0.2 0.0005 20.1 0.2 2.0 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 RKO99174.1 - 0.0049 17.0 1.4 0.0096 16.0 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 RKO99175.1 - 3.5e-32 110.3 0.4 1.3e-16 60.4 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 RKO99175.1 - 1.4e-16 60.7 0.3 2.9e-16 59.6 0.3 1.6 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 RKO99175.1 - 5.1e-09 35.5 1.3 1.1e-08 34.4 1.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 RKO99175.1 - 0.041 13.6 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.11 RKO99175.1 - 0.042 13.8 1.3 0.11 12.4 1.3 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Octopine_DH PF02317.17 RKO99175.1 - 0.048 13.8 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Elf1 PF05129.13 RKO99175.1 - 0.18 11.9 0.8 0.48 10.5 0.8 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Prok-RING_4 PF14447.6 RKO99175.1 - 0.53 10.2 2.2 7.3 6.5 1.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn-ribbon_8 PF09723.10 RKO99175.1 - 1.4 9.1 3.0 6.8 6.9 3.0 2.2 1 1 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 RKO99175.1 - 3.4 7.7 7.3 1.5 8.8 3.3 2.3 2 0 0 2 2 2 0 Nudix N-terminal HBS1_N PF08938.10 RKO99175.1 - 3.8 7.9 10.0 8.4e+02 0.4 10.0 3.2 1 1 0 1 1 1 0 HBS1 N-terminus zf-RRN7 PF11781.8 RKO99175.1 - 9.2 6.1 6.3 2.7 7.7 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Mito_carr PF00153.27 RKO99176.1 - 5.5e-59 196.1 10.5 4e-22 77.9 0.0 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein TFIID-31kDa PF02291.15 RKO99177.1 - 0.082 13.0 0.3 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RsbRD_N PF14361.6 RKO99177.1 - 0.65 10.7 7.4 0.89 10.3 0.1 3.6 3 1 1 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Choline_transpo PF04515.12 RKO99178.1 - 1.1e-73 248.3 20.2 1.1e-73 248.3 20.2 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter SHS2_Rpb7-N PF03876.17 RKO99179.1 - 6.4e-15 55.3 0.1 1.1e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 RKO99179.1 - 1e-08 35.4 0.0 9.2e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 RKO99179.1 - 0.0011 19.2 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 zf-CCCH PF00642.24 RKO99180.1 - 7.1 6.7 10.2 2.1 8.3 0.2 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) INTS2 PF14750.6 RKO99181.1 - 2.9e-17 61.6 0.0 1e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Integrator complex subunit 2 NOA36 PF06524.12 RKO99181.1 - 4.4 6.5 11.9 6.8 5.9 11.9 1.1 1 0 0 1 1 1 0 NOA36 protein ANAPC4_WD40 PF12894.7 RKO99182.1 - 2.3e-10 40.6 0.1 3.3e-05 24.1 0.1 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKO99182.1 - 4.8e-08 33.5 10.4 0.0016 19.2 1.3 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat VID27 PF08553.10 RKO99182.1 - 0.00015 21.0 0.1 0.029 13.4 0.0 2.2 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain CTC1 PF15489.6 RKO99183.1 - 0.0073 13.9 0.0 1.3 6.4 0.0 2.2 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 GTP1_OBG PF01018.22 RKO99184.1 - 1.3e-32 112.5 0.4 1.8e-32 112.1 0.4 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 RKO99184.1 - 1.5e-21 76.6 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO99184.1 - 7.6e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 RKO99184.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 RKO99184.1 - 0.0087 15.6 0.0 0.37 10.3 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 RKO99184.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family MeaB PF03308.16 RKO99184.1 - 0.098 11.6 0.1 0.53 9.2 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RKO99184.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 RKO99184.1 - 0.13 12.3 0.0 11 6.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family SHQ1 PF04925.15 RKO99185.1 - 2.3e-50 170.6 0.7 3e-50 170.2 0.7 1.1 1 0 0 1 1 1 1 SHQ1 protein DUF4870 PF09685.10 RKO99186.1 - 0.027 14.6 3.6 0.041 14.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) VKOR PF07884.14 RKO99186.1 - 0.47 10.6 12.3 1.2 9.4 12.3 1.5 1 1 0 1 1 1 0 Vitamin K epoxide reductase family Acyl-CoA_dh_1 PF00441.24 RKO99187.1 - 7e-40 136.7 0.1 9.1e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKO99187.1 - 1.8e-16 60.1 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKO99187.1 - 3.6e-14 53.2 0.2 4.9e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SCP2 PF02036.17 RKO99189.1 - 2.4e-25 88.9 0.5 2.8e-25 88.7 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RKO99189.1 - 6.6e-06 26.4 0.2 8.2e-06 26.1 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ThiF PF00899.21 RKO99190.1 - 5.4e-18 65.2 0.0 5.5e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family VWA_3 PF13768.6 RKO99190.1 - 0.026 14.5 0.1 0.059 13.3 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain TPR_12 PF13424.6 RKO99190.1 - 0.092 13.1 2.5 0.63 10.4 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat AdoHcyase PF05221.17 RKO99191.1 - 1.1e-137 458.2 0.0 1.1e-75 254.5 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RKO99191.1 - 1.1e-87 292.2 3.5 1.8e-87 291.5 3.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RKO99191.1 - 7.8e-10 38.4 0.3 1.8e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RKO99191.1 - 8.8e-06 25.4 0.2 1.8e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 RKO99191.1 - 0.012 14.9 1.6 0.04 13.2 1.6 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 RKO99191.1 - 0.019 15.2 0.2 0.046 14.0 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 RKO99193.1 - 2.4e-49 168.1 0.0 2.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99193.1 - 4.2e-19 68.8 0.0 5.1e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO99193.1 - 6.3e-06 25.2 0.0 8.9e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKO99193.1 - 0.00065 19.1 0.3 0.0036 16.7 0.1 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKO99193.1 - 0.0024 17.2 0.0 0.0051 16.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RKO99193.1 - 0.0078 16.2 0.9 0.015 15.2 0.9 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKO99193.1 - 0.034 13.8 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ADH_N PF08240.12 RKO99194.1 - 5.7e-25 87.3 1.8 1e-24 86.5 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKO99194.1 - 2.4e-24 85.8 0.1 4.6e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RKO99194.1 - 7.9e-05 23.7 0.0 0.00015 22.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 RKO99194.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 RKO99194.1 - 0.021 14.1 0.4 0.034 13.4 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 RKO99194.1 - 0.024 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 RKO99194.1 - 0.073 12.5 0.0 0.23 10.9 0.0 1.9 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Cytochrom_C PF00034.21 RKO99196.1 - 5.6e-12 46.6 0.0 7.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 RKO99196.1 - 2.2e-07 31.1 2.4 1.4e-06 28.5 2.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 RKO99196.1 - 0.00025 20.8 0.3 0.0032 17.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain RRM_1 PF00076.22 RKO99197.1 - 6e-66 218.2 0.1 2.3e-16 59.3 0.0 8.0 5 3 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKO99197.1 - 5.9e-07 29.1 0.0 0.044 13.4 0.0 3.5 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO99197.1 - 0.0042 17.2 0.0 0.81 9.8 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 RKO99197.1 - 0.018 15.2 3.9 24 5.1 0.0 4.8 6 0 0 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter Rhamno_transf PF11316.8 RKO99197.1 - 0.028 13.8 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF5089 PF17002.5 RKO99199.1 - 0.0001 22.3 0.6 0.0001 22.3 0.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF5089) DegS PF05384.11 RKO99199.1 - 0.0029 17.1 0.4 0.0029 17.1 0.4 2.8 2 1 1 3 3 3 1 Sensor protein DegS phiKZ_IP PF12699.7 RKO99199.1 - 0.0087 15.2 0.1 0.0087 15.2 0.1 2.0 2 1 0 2 2 2 1 phiKZ-like phage internal head proteins DUF16 PF01519.16 RKO99199.1 - 0.013 16.0 2.0 0.013 16.0 2.0 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 CENP-Q PF13094.6 RKO99199.1 - 0.013 15.7 8.3 0.049 13.8 0.0 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0203 PF05254.12 RKO99199.1 - 0.051 13.8 0.9 0.14 12.4 0.9 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) TMPIT PF07851.13 RKO99199.1 - 0.054 12.7 6.3 0.47 9.6 0.1 2.3 2 1 0 2 2 2 0 TMPIT-like protein Spectrin PF00435.21 RKO99199.1 - 0.14 12.7 0.4 0.14 12.7 0.4 3.0 2 1 1 3 3 3 0 Spectrin repeat BLOC1_2 PF10046.9 RKO99199.1 - 0.52 10.6 10.2 0.12 12.7 2.2 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SpecificRecomb PF10136.9 RKO99199.1 - 0.67 8.2 2.0 1.2 7.4 2.0 1.3 1 0 0 1 1 1 0 Site-specific recombinase DUF948 PF06103.11 RKO99199.1 - 1 9.7 6.6 0.3 11.4 2.4 2.4 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.6 RKO99199.1 - 2.1 8.4 7.4 9.1 6.3 0.2 2.9 2 1 1 3 3 3 0 FlxA-like protein DUF1664 PF07889.12 RKO99199.1 - 2.4 8.2 11.5 0.77 9.8 2.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 RKO99199.1 - 4.3 6.6 9.6 3.4 6.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 RKO99199.1 - 6.2 7.6 10.2 1.8 9.3 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Vma12 PF11712.8 RKO99200.1 - 7e-13 48.8 0.0 9.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1631 PF07793.11 RKO99200.1 - 1.6 7.0 9.5 2.2 6.6 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ATP19 PF11022.8 RKO99201.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit K PIG-H PF10181.9 RKO99202.1 - 2.2e-08 33.8 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Polysacc_synt_4 PF04669.13 RKO99203.1 - 2.3e-16 59.9 0.4 1.4e-09 37.7 0.1 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis GH97_N PF14508.6 RKO99203.1 - 0.036 13.5 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal AAA PF00004.29 RKO99204.1 - 9.9e-40 136.0 0.0 1.6e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO99204.1 - 1.4e-09 37.6 0.3 8.3e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 RKO99204.1 - 1.2e-07 31.8 0.1 3.7e-07 30.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKO99204.1 - 5.3e-07 29.5 0.0 8.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKO99204.1 - 6.5e-06 26.5 0.2 0.0017 18.6 0.0 2.9 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 RKO99204.1 - 6.5e-06 26.6 2.4 0.00011 22.6 2.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 RKO99204.1 - 1.2e-05 25.0 0.9 0.0033 17.0 0.1 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RKO99204.1 - 9.4e-05 22.2 0.0 0.00029 20.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Vps4_C PF09336.10 RKO99204.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 RKO99204.1 - 0.00031 20.9 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 RKO99204.1 - 0.00083 18.8 0.0 1.6 8.1 0.0 2.7 3 0 0 3 3 3 2 Bacterial TniB protein TIP49 PF06068.13 RKO99204.1 - 0.0012 18.1 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 RKO99204.1 - 0.0015 17.9 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RKO99204.1 - 0.0035 16.5 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 RKO99204.1 - 0.0049 16.8 0.0 0.041 13.8 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.6 RKO99204.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RKO99204.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO99204.1 - 0.0073 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RKO99204.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 RKO99204.1 - 0.017 15.7 0.0 0.035 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKO99204.1 - 0.027 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 RKO99204.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RKO99204.1 - 0.033 14.5 0.1 0.07 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKO99204.1 - 0.033 13.9 0.2 0.089 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RKO99204.1 - 0.051 13.4 0.0 1.1 9.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 RKO99204.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 RKO99204.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 RKO99204.1 - 0.11 11.8 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 RKO99204.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 RKO99204.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SMC_N PF02463.19 RKO99204.1 - 0.16 11.4 0.0 1.3 8.4 0.0 2.0 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 RKO99204.1 - 0.17 12.2 0.1 0.44 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RKO99204.1 - 0.21 12.1 0.0 1.9 9.0 0.0 2.1 1 1 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 RKO99204.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 RKO99204.1 - 0.25 11.2 0.0 0.91 9.4 0.0 1.7 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Kinesin PF00225.23 RKO99206.1 - 6.2e-96 321.2 0.7 7.4e-96 321.0 0.7 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO99206.1 - 6.2e-25 87.9 0.1 1.4e-24 86.8 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding Cwf_Cwc_15 PF04889.12 RKO99207.1 - 0.096 12.4 3.5 0.16 11.7 3.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Elongin_A PF06881.11 RKO99208.1 - 3.8e-18 65.9 1.4 1.7e-17 63.9 0.7 2.2 1 1 1 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SOCS_box PF07525.16 RKO99208.1 - 0.067 13.6 0.7 0.11 12.8 0.7 1.4 1 0 0 1 1 1 0 SOCS box Pkinase PF00069.25 RKO99209.1 - 8.4e-73 245.0 0.0 1.1e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99209.1 - 9.4e-50 169.3 0.0 1.5e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RKO99209.1 - 5.1e-20 71.6 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 RKO99209.1 - 1.5e-10 41.5 0.5 2.8e-10 40.7 0.5 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 RKO99209.1 - 1.1e-07 31.5 0.0 2.9e-07 30.1 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKO99209.1 - 2.5e-05 23.2 0.1 3.6e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 RKO99209.1 - 0.0027 18.1 0.6 0.1 13.0 0.6 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 RKO99209.1 - 0.0081 15.1 0.2 0.019 13.9 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKO99209.1 - 0.013 15.5 0.6 0.013 15.5 0.6 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 RKO99209.1 - 0.11 11.8 0.1 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RKO99209.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3760 PF12586.8 RKO99210.1 - 0.00053 20.1 0.0 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3760) DUF938 PF06080.12 RKO99210.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) WD40 PF00400.32 RKO99211.1 - 3.3e-37 125.8 23.2 1.4e-05 25.7 0.3 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 RKO99211.1 - 5.2e-07 29.5 0.1 1.2e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RKO99211.1 - 8e-07 28.8 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 RKO99211.1 - 8.9e-06 25.9 0.4 1.1 9.7 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 RKO99211.1 - 0.00012 22.1 0.0 1.6 8.8 0.0 4.3 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 RKO99211.1 - 0.00016 21.6 0.1 0.00035 20.4 0.1 1.6 1 0 0 1 1 1 1 F-box CDC4_D PF16856.5 RKO99211.1 - 0.031 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain Nup160 PF11715.8 RKO99211.1 - 0.037 12.7 1.4 4.4 5.8 0.0 3.5 4 0 0 4 4 4 0 Nucleoporin Nup120/160 zf-RING_4 PF14570.6 RKO99212.1 - 1.1e-20 73.1 13.8 1.1e-20 73.1 13.8 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 RKO99212.1 - 1.5e-05 24.7 0.3 0.00022 21.0 0.3 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 RKO99212.1 - 2.1e-05 24.3 10.2 4.8e-05 23.1 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO99212.1 - 9.5e-05 22.7 11.5 9.5e-05 22.7 11.5 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 RKO99212.1 - 0.00013 21.8 9.1 0.0075 16.1 5.7 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-UDP PF14569.6 RKO99212.1 - 0.0044 17.1 8.4 0.0059 16.7 5.2 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger Nup35_RRM PF05172.13 RKO99212.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 RKO99212.1 - 0.008 16.1 8.8 0.012 15.5 7.8 1.8 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Torus PF16131.5 RKO99212.1 - 0.0082 16.8 3.3 0.011 16.4 0.1 2.2 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 RKO99212.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-Di19 PF05605.12 RKO99212.1 - 0.22 11.8 4.0 1.8 8.9 1.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 RKO99212.1 - 2.5 8.2 10.9 2.7 8.1 6.2 2.3 2 0 0 2 2 2 0 RING-type zinc-finger DRIM PF07539.12 RKO99213.1 - 1.3e-36 126.2 0.0 2e-35 122.3 0.0 3.0 4 1 0 4 4 4 1 Down-regulated in metastasis DUF3756 PF12581.8 RKO99213.1 - 0.058 13.3 0.3 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) CLASP_N PF12348.8 RKO99213.1 - 0.076 12.6 10.2 0.054 13.1 1.3 4.4 4 1 0 4 4 4 0 CLASP N terminal DUF1682 PF07946.14 RKO99213.1 - 0.5 9.5 9.4 0.97 8.6 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HEAT PF02985.22 RKO99213.1 - 2.1 8.8 4.1 10 6.7 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat TAF6_C PF07571.13 RKO99214.1 - 1.3e-28 99.1 0.0 2.6e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 RKO99214.1 - 1.9e-18 66.4 1.8 2.6e-18 66.0 0.7 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 RKO99214.1 - 0.00044 20.6 0.6 0.00074 19.9 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 RKO99214.1 - 0.0019 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HEAT_EZ PF13513.6 RKO99214.1 - 0.0047 17.4 0.8 0.042 14.4 0.1 2.9 2 1 0 2 2 2 1 HEAT-like repeat CENP-T_C PF15511.6 RKO99214.1 - 0.12 12.5 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RKO99214.1 - 0.18 12.2 0.2 0.32 11.4 0.2 1.3 1 0 0 1 1 1 0 CENP-S protein HEAT_PBS PF03130.16 RKO99214.1 - 6.3 7.8 10.1 15 6.6 0.3 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Ribosomal_L27e PF01777.18 RKO99215.1 - 2.5e-27 95.0 3.4 3.4e-27 94.6 3.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 RKO99215.1 - 0.00024 20.9 0.1 0.00067 19.5 0.1 1.7 1 0 0 1 1 1 1 KOW motif NIF PF03031.18 RKO99216.1 - 9.8e-56 187.9 0.1 1.2e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Rad51 PF08423.11 RKO99217.1 - 2.1e-30 105.8 0.0 3.9e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 RKO99217.1 - 6.6e-09 35.6 0.7 1.6e-07 31.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 RKO99217.1 - 0.0071 15.8 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 RKO99217.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 RKO99217.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RKO99217.1 - 0.048 13.9 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RKO99217.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Aminotran_1_2 PF00155.21 RKO99218.1 - 2.6e-13 49.9 0.0 3.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cwf_Cwc_15 PF04889.12 RKO99220.1 - 0.23 11.2 2.4 0.42 10.3 2.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 RKO99220.1 - 0.27 11.1 0.3 0.52 10.2 0.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region tRNA-synt_1e PF01406.19 RKO99221.1 - 7.6e-127 422.8 0.0 1.2e-126 422.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RKO99221.1 - 1.4e-07 30.6 2.2 0.00011 21.1 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RKO99221.1 - 3.4e-05 22.3 0.0 0.00028 19.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 RKO99221.1 - 5.9e-05 23.5 0.1 5.9e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.21 RKO99221.1 - 0.05 12.5 2.1 0.12 11.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PA PF02225.22 RKO99221.1 - 0.16 12.0 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 PA domain Flavoprotein PF02441.19 RKO99222.1 - 7e-45 152.6 0.2 8.5e-45 152.3 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein Herpes_UL37_1 PF03970.13 RKO99222.1 - 0.04 13.1 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein Voldacs PF03517.13 RKO99223.1 - 2.8e-14 53.4 0.2 4.9e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orthopox_B11R PF07033.11 RKO99226.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Bcr-Abl_Oligo PF09036.10 RKO99226.1 - 0.096 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Acyl-CoA_dh_1 PF00441.24 RKO99227.1 - 1.2e-32 113.2 2.8 1.7e-32 112.7 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKO99227.1 - 6.2e-19 68.0 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKO99227.1 - 7.7e-15 55.4 8.6 7.7e-15 55.4 8.6 1.8 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RKO99227.1 - 1.3e-12 48.4 0.0 3.8e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain LIM PF00412.22 RKO99228.1 - 1.5e-34 118.0 29.9 1.2e-14 54.3 2.9 3.1 3 0 0 3 3 3 3 LIM domain zf-RING_6 PF14835.6 RKO99228.1 - 0.014 15.3 5.0 0.014 15.3 5.0 2.6 2 1 1 3 3 3 0 zf-RING of BARD1-type protein zf_UBZ PF18439.1 RKO99228.1 - 0.11 12.1 0.0 0.11 12.1 0.0 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger MINDY_DUB PF04424.13 RKO99229.1 - 2.4e-22 79.1 0.0 3.9e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Prp18 PF02840.15 RKO99230.1 - 2.1e-59 199.6 0.1 2.8e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 RKO99230.1 - 3.7e-10 39.2 6.5 3.7e-10 39.2 6.5 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DRIM PF07539.12 RKO99230.1 - 0.04 12.2 0.0 0.057 11.7 0.0 1.2 1 0 0 1 1 1 0 Down-regulated in metastasis START PF01852.19 RKO99231.1 - 4.8e-06 26.1 0.0 0.0006 19.3 0.0 2.3 1 1 0 1 1 1 1 START domain Ribosomal_S8 PF00410.19 RKO99232.1 - 5.3e-23 81.4 0.1 9.1e-23 80.6 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 GATA PF00320.27 RKO99233.1 - 5.1e-26 90.0 17.0 2.4e-13 49.4 1.4 2.2 2 0 0 2 2 2 2 GATA zinc finger DZR PF12773.7 RKO99233.1 - 0.00026 20.9 5.8 0.0021 18.0 6.4 2.1 1 1 1 2 2 2 2 Double zinc ribbon TDP43_N PF18694.1 RKO99233.1 - 0.052 13.4 0.1 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain OTT_1508_deam PF14441.6 RKO99233.1 - 0.21 11.6 3.7 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 OTT_1508-like deaminase OrfB_Zn_ribbon PF07282.11 RKO99233.1 - 0.98 9.4 7.7 0.34 10.9 0.3 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ArfGap PF01412.18 RKO99233.1 - 0.99 9.5 6.9 2.1 8.5 0.1 2.1 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zf-B_box PF00643.24 RKO99233.1 - 7.5 6.8 9.7 25 5.1 0.1 3.4 4 0 0 4 4 4 0 B-box zinc finger SpoU_methylase PF00588.19 RKO99234.1 - 9.6e-14 51.8 0.0 1.2e-07 32.0 0.0 3.8 2 2 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RKO99234.1 - 0.00015 22.0 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding Tht1 PF04163.12 RKO99235.1 - 1e-05 24.5 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein DMPK_coil PF08826.10 RKO99235.1 - 0.014 15.5 0.2 0.014 15.5 0.2 2.7 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF1846 PF08903.11 RKO99235.1 - 4.2 5.8 5.5 7.3 5.0 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Linker_histone PF00538.19 RKO99236.1 - 4.8e-17 62.1 0.0 4.8e-17 62.1 0.0 2.4 3 0 0 3 3 3 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 RKO99236.1 - 5.5 6.7 11.2 6.9 6.4 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-RING_2 PF13639.6 RKO99237.1 - 4.8e-09 36.4 5.4 7e-09 35.9 3.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 RKO99237.1 - 1.8e-08 34.5 0.8 1.8e-08 34.5 0.8 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RKO99237.1 - 3.5e-06 26.8 0.6 7.4e-06 25.7 0.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO99237.1 - 3e-05 23.8 7.0 4.1e-05 23.3 4.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO99237.1 - 0.00047 20.1 4.3 0.0014 18.6 4.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 RKO99237.1 - 0.026 14.3 0.3 0.026 14.3 0.3 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 RKO99237.1 - 0.033 14.2 1.6 0.08 13.0 1.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RKO99237.1 - 0.16 11.9 7.6 0.013 15.4 2.6 1.8 2 0 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 RKO99237.1 - 0.19 11.9 0.2 0.42 10.8 0.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 RKO99237.1 - 0.2 11.6 9.9 0.13 12.1 6.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RKO99237.1 - 0.32 10.9 6.9 0.27 11.1 4.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RKO99237.1 - 0.86 9.3 2.8 1.4 8.6 2.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Response_reg PF00072.24 RKO99240.1 - 6.2e-26 90.8 0.1 1.6e-25 89.5 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 RKO99240.1 - 1e-22 80.7 0.0 3.2e-21 75.9 0.0 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 RKO99240.1 - 0.0037 17.3 0.1 0.023 14.7 0.0 2.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 RKO99240.1 - 0.058 13.3 0.0 9.3 6.2 0.0 3.1 3 0 0 3 3 3 0 GHKL domain FSA_C PF10479.9 RKO99240.1 - 0.85 7.7 6.2 1.5 6.9 6.2 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Lactamase_B_4 PF13691.6 RKO99241.1 - 2e-14 53.0 0.0 8.5e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 RKO99241.1 - 2.5e-07 30.4 4.5 0.00046 19.8 0.2 4.0 3 1 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RKO99241.1 - 0.0011 19.0 0.1 0.0031 17.5 0.1 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Acyl-CoA_dh_1 PF00441.24 RKO99242.1 - 1.9e-45 154.8 1.1 2.9e-45 154.1 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RKO99242.1 - 3.3e-28 98.6 1.1 8.9e-28 97.2 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RKO99242.1 - 5.9e-24 84.1 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKO99242.1 - 1.5e-20 73.9 2.3 2.6e-20 73.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Adap_comp_sub PF00928.21 RKO99244.1 - 1.2e-70 237.9 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 RKO99244.1 - 0.0026 17.2 0.1 0.0079 15.7 0.0 1.7 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 RKO99244.1 - 0.0035 17.3 0.2 0.0069 16.3 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNF2_N PF00176.23 RKO99245.1 - 3.3e-71 239.8 1.7 5.8e-71 239.0 0.2 2.1 2 1 1 3 3 3 1 SNF2 family N-terminal domain SLIDE PF09111.10 RKO99245.1 - 9.1e-40 135.2 0.6 3.1e-39 133.5 0.6 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 RKO99245.1 - 2.6e-22 79.7 1.0 2.6e-22 79.7 1.0 3.1 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 RKO99245.1 - 4.4e-18 65.6 0.0 2.4e-17 63.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO99245.1 - 3.9e-07 30.2 0.0 2.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 RKO99245.1 - 0.014 15.0 0.0 0.053 13.2 0.0 2.1 2 1 0 2 2 2 0 SWI2/SNF2 ATPase Orn_Arg_deC_N PF02784.16 RKO99246.1 - 2e-77 259.9 0.0 2.6e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RKO99246.1 - 7.7e-20 71.0 0.0 9.5e-20 70.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DEAD PF00270.29 RKO99248.1 - 8.3e-48 162.5 0.0 1.2e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO99248.1 - 5e-31 107.3 0.0 2.3e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO99248.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 RKO99248.1 - 0.037 12.8 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 RKO99248.1 - 0.22 11.8 0.2 2 8.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 RKO99248.1 - 0.25 10.1 0.0 6.5 5.4 0.0 2.2 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 His_biosynth PF00977.21 RKO99249.1 - 3.2e-19 69.3 0.0 4.5e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein RPAP1_C PF08620.10 RKO99250.1 - 4.6e-16 58.7 0.2 1.1e-15 57.4 0.2 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 RKO99250.1 - 8.1e-08 31.9 0.3 1.8e-07 30.8 0.3 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal PMT PF02366.18 RKO99251.1 - 1.4e-77 260.6 19.9 1.4e-77 260.6 19.9 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 RKO99251.1 - 6.1e-58 195.7 17.9 6.1e-58 195.7 17.9 2.3 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 RKO99251.1 - 1.5e-27 96.7 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 MIR domain PsbT PF01405.17 RKO99251.1 - 0.084 12.7 0.1 0.084 12.7 0.1 3.6 4 0 0 4 4 4 0 Photosystem II reaction centre T protein Atg8 PF02991.16 RKO99253.1 - 5.3e-45 151.9 0.0 6.6e-45 151.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RKO99253.1 - 7.6e-06 26.2 0.0 9.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 RKO99253.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 PKcGMP_CC PF16808.5 RKO99254.1 - 0.0024 17.7 0.6 0.0057 16.5 0.6 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 RKO99254.1 - 0.015 15.9 2.8 0.08 13.6 2.8 2.3 1 0 0 1 1 1 0 SlyX DUF724 PF05266.14 RKO99254.1 - 0.021 14.7 1.3 0.037 13.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Csm1_N PF18504.1 RKO99254.1 - 0.2 12.0 1.0 0.45 10.9 1.0 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 RKO99255.1 - 0 1026.7 0.0 0 1026.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Flavin_Reduct PF01613.18 RKO99256.1 - 1e-20 74.4 0.1 1.4e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain ADK PF00406.22 RKO99258.1 - 1.9e-42 144.9 0.0 2.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RKO99258.1 - 3.3e-18 66.4 0.0 6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 RKO99258.1 - 1.9e-15 56.5 0.0 3.5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 RKO99258.1 - 0.00029 21.4 0.0 0.00047 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO99258.1 - 0.0078 16.4 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RKO99258.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 RKO99258.1 - 0.032 14.2 0.1 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ribosomal_L37 PF08561.10 RKO99259.1 - 6.5e-15 55.7 0.5 1e-14 55.1 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 CPG4 PF15481.6 RKO99260.1 - 0.038 14.6 1.3 0.063 13.9 1.3 1.4 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 YjeJ PF15922.5 RKO99260.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 YjeJ-like DSPn PF14671.6 RKO99261.1 - 2.2e-39 135.1 0.2 1.4e-38 132.6 0.1 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RKO99261.1 - 6.1e-13 48.7 0.1 1.8e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO99261.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RKO99261.1 - 0.00029 21.0 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RKO99261.1 - 0.00086 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family HI0933_like PF03486.14 RKO99261.1 - 0.023 13.4 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Y_phosphatase2 PF03162.13 RKO99261.1 - 0.05 13.2 0.0 0.2 11.2 0.0 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family PMI_typeI PF01238.21 RKO99262.1 - 2.9e-114 382.2 0.0 3.4e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 RKO99262.1 - 7.3e-06 25.6 0.0 0.0086 15.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain PALP PF00291.25 RKO99263.1 - 9.8e-76 255.0 1.8 1.3e-75 254.5 1.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 RKO99263.1 - 2.3e-38 129.8 0.0 5.5e-19 67.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase SKIP_SNW PF02731.15 RKO99264.1 - 5e-52 175.8 1.3 5e-52 175.8 1.3 1.9 2 0 0 2 2 2 1 SKIP/SNW domain T4SS-DNA_transf PF02534.14 RKO99264.1 - 0.35 9.6 1.2 0.37 9.5 0.3 1.5 1 1 1 2 2 2 0 Type IV secretory system Conjugative DNA transfer MSC PF09402.10 RKO99265.1 - 8.4e-10 38.6 0.0 2e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 Man1-Src1p-C-terminal domain SDA1 PF05285.12 RKO99265.1 - 0.015 14.8 1.4 0.022 14.2 1.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RKO99265.1 - 0.51 8.5 1.6 0.71 8.0 1.6 1.1 1 0 0 1 1 1 0 Nop14-like family AhpC-TSA PF00578.21 RKO99266.1 - 1.8e-29 102.2 0.0 2.5e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO99266.1 - 4.6e-13 49.1 0.0 6.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RKO99266.1 - 4.3e-11 42.5 0.0 8.1e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin CDP-OH_P_transf PF01066.21 RKO99268.1 - 1.6e-16 60.8 0.1 1.6e-16 60.8 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Aminotran_3 PF00202.21 RKO99269.1 - 1.1e-109 366.8 0.1 1.4e-109 366.5 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III AAA_23 PF13476.6 RKO99270.1 - 0.06 13.8 0.1 0.06 13.8 0.1 6.9 4 2 0 4 4 4 0 AAA domain AA_permease PF00324.21 RKO99271.1 - 4.4e-37 127.8 45.7 3.6e-23 81.9 27.2 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 RKO99271.1 - 8.2e-29 100.9 0.0 1.4e-15 57.3 0.1 3.1 2 1 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 RKO99271.1 - 1e-11 44.4 44.0 2.7e-10 39.7 27.8 2.1 2 0 0 2 2 2 2 Amino acid permease DUF726 PF05277.12 RKO99272.1 - 8.7e-53 179.4 0.6 9.5e-53 179.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LCAT PF02450.15 RKO99272.1 - 0.028 13.6 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 RKO99272.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RKO99272.1 - 0.073 13.7 2.0 0.092 13.3 1.8 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.8 RKO99272.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Ras PF00071.22 RKO99273.1 - 6.7e-55 185.1 0.0 7.7e-55 184.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO99273.1 - 4.1e-32 110.9 0.0 5.9e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO99273.1 - 4.9e-15 55.4 0.0 6.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKO99273.1 - 9.4e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RKO99273.1 - 0.00035 20.2 0.0 0.00082 19.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKO99273.1 - 0.00043 20.3 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 RKO99273.1 - 0.0089 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 RKO99273.1 - 0.011 15.7 0.0 0.064 13.2 0.0 2.0 2 1 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 RKO99273.1 - 0.012 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 RKO99273.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RKO99273.1 - 0.016 15.4 0.0 0.062 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RKO99273.1 - 0.047 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 RKO99273.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 RKO99273.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 RKO99273.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 RKO99273.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin CBFD_NFYB_HMF PF00808.23 RKO99274.1 - 4e-12 46.2 0.0 5.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RKO99274.1 - 0.0023 18.3 0.0 0.0034 17.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Methyltransf_16 PF10294.9 RKO99275.1 - 1.1e-23 83.9 0.0 1.8e-11 44.1 0.0 2.9 2 1 0 2 2 2 2 Lysine methyltransferase DUF2201 PF09967.9 RKO99275.1 - 0.063 13.4 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 VWA-like domain (DUF2201) MTS PF05175.14 RKO99275.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ARS2 PF04959.13 RKO99276.1 - 2.3e-22 80.3 0.0 5.5e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 RKO99276.1 - 2.7e-14 53.3 0.0 5.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) zf-C2H2 PF00096.26 RKO99276.1 - 0.034 14.6 0.8 0.062 13.8 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1993 PF09351.10 RKO99276.1 - 1.7 8.8 5.7 16 5.6 0.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) zf-CCHC PF00098.23 RKO99277.1 - 2.1e-10 40.2 27.1 0.0026 17.8 0.2 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 RKO99277.1 - 0.0016 18.1 23.9 0.029 14.1 0.5 3.7 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.6 RKO99277.1 - 0.0025 17.7 1.9 0.0025 17.7 1.9 4.0 2 1 2 4 4 4 2 Zinc knuckle zf-CCHC_2 PF13696.6 RKO99277.1 - 0.38 10.6 0.3 0.38 10.6 0.3 3.9 5 0 0 5 5 5 0 Zinc knuckle Cyt-b5 PF00173.28 RKO99278.1 - 6.3e-09 35.8 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DSBA PF01323.20 RKO99279.1 - 0.13 12.0 2.3 0.96 9.2 2.3 2.3 1 1 0 1 1 1 0 DSBA-like thioredoxin domain PP2C PF00481.21 RKO99280.1 - 8.2e-75 251.8 0.0 1.1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RKO99280.1 - 9.9e-05 22.3 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) TB2_DP1_HVA22 PF03134.19 RKO99281.1 - 4.5e-12 45.7 2.1 4.5e-12 45.7 2.1 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family SUI1 PF01253.22 RKO99282.1 - 6.1e-25 87.5 0.1 8.6e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Gti1_Pac2 PF09729.9 RKO99284.1 - 1.9e-26 93.3 0.0 2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family TFIIA PF03153.13 RKO99285.1 - 0.00055 20.0 7.8 0.00055 20.0 7.8 3.9 4 0 0 4 4 4 2 Transcription factor IIA, alpha/beta subunit SH3_9 PF14604.6 RKO99285.1 - 0.0038 17.1 0.2 0.0083 16.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4637 PF15470.6 RKO99285.1 - 0.037 13.8 1.2 0.099 12.4 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 RKO99285.1 - 5.8 5.0 17.9 12 3.9 17.9 1.4 1 0 0 1 1 1 0 Nop14-like family DUF677 PF05055.12 RKO99286.1 - 0.21 10.4 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Troponin PF00992.20 RKO99286.1 - 0.33 11.3 1.6 0.29 11.4 0.2 1.6 2 0 0 2 2 2 0 Troponin TPR_1 PF00515.28 RKO99287.1 - 1.3e-29 100.8 5.0 1.3e-07 31.1 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99287.1 - 2.9e-28 95.7 8.6 1.4e-06 27.9 0.2 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99287.1 - 1.1e-24 85.8 9.2 7.3e-07 28.8 0.0 5.1 3 1 2 5 5 5 4 TPR repeat TPR_16 PF13432.6 RKO99287.1 - 8e-22 77.6 17.4 4.1e-09 36.9 1.7 4.6 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 RKO99287.1 - 1.1e-21 75.7 19.5 1.3e-05 25.6 0.4 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99287.1 - 1.4e-18 65.5 1.1 0.00016 21.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99287.1 - 5.5e-18 64.0 2.5 5.3e-06 26.4 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 RKO99287.1 - 1.5e-16 60.6 10.5 7.7e-05 23.1 0.1 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99287.1 - 2e-15 55.6 3.8 0.0009 19.1 0.2 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 RKO99287.1 - 8.4e-13 48.3 16.1 1.4e-05 25.2 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 RKO99287.1 - 9.7e-11 41.9 4.6 0.0056 17.0 0.3 4.5 2 2 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO99287.1 - 1.1e-09 38.3 3.0 0.00033 20.8 0.7 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RKO99287.1 - 1.8e-09 37.7 11.0 0.35 11.2 0.0 4.9 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99287.1 - 6.3e-08 32.8 7.6 0.3 11.8 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 RKO99287.1 - 2.8e-05 24.6 6.2 0.004 17.6 0.1 3.7 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_3 PF07720.12 RKO99287.1 - 3.4e-05 23.7 0.5 0.31 11.1 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 RKO99287.1 - 0.00016 21.0 6.4 0.027 13.7 0.2 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKO99287.1 - 0.00028 20.9 3.3 1.3 9.2 0.0 3.9 4 1 0 4 4 3 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 RKO99287.1 - 0.00047 20.2 1.1 12 6.1 0.1 4.5 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 RKO99287.1 - 0.00047 19.9 14.3 0.28 11.1 0.6 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TOM20_plant PF06552.12 RKO99287.1 - 0.0053 16.5 0.3 8.4 6.1 0.0 3.7 2 2 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 RPN7 PF10602.9 RKO99287.1 - 0.031 14.0 0.1 0.43 10.3 0.1 2.8 1 1 0 1 1 1 0 26S proteasome subunit RPN7 MAS20 PF02064.15 RKO99287.1 - 0.051 13.7 0.6 31 4.7 0.0 3.5 3 1 0 4 4 4 0 MAS20 protein import receptor TPR_21 PF09976.9 RKO99287.1 - 0.5 10.0 5.1 1 9.1 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain DUF1712 PF08217.11 RKO99288.1 - 1.9e-06 26.7 0.0 2.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) ATP_sub_h PF10775.9 RKO99288.1 - 0.13 12.2 0.1 0.47 10.5 0.1 1.9 1 0 0 1 1 1 0 ATP synthase complex subunit h Acetyltransf_1 PF00583.25 RKO99290.1 - 8.1e-11 42.2 0.0 1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKO99290.1 - 2.4e-07 31.1 0.2 3.8e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKO99290.1 - 1.2e-06 28.5 0.1 1.5e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKO99290.1 - 2.7e-05 24.1 0.1 4.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 RKO99290.1 - 0.026 14.6 0.1 0.046 13.8 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1825 PF08855.10 RKO99291.1 - 0.097 12.6 5.2 3 7.8 1.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) Amelotin PF15757.5 RKO99292.1 - 0.015 14.8 0.7 0.02 14.5 0.7 1.2 1 0 0 1 1 1 0 Amelotin CsbD PF05532.12 RKO99293.1 - 1.4e-09 37.7 7.0 1.8e-09 37.3 7.0 1.2 1 0 0 1 1 1 1 CsbD-like ATP-synt_B PF00430.18 RKO99293.1 - 0.16 12.1 4.7 0.21 11.7 4.7 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Pkinase PF00069.25 RKO99294.1 - 1e-54 185.7 0.0 1.2e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99294.1 - 3.3e-29 102.0 0.0 4.5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO99294.1 - 3.4e-10 39.7 0.0 6.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO99294.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RKO99294.1 - 0.13 12.2 0.1 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Spt20 PF12090.8 RKO99295.1 - 0.0016 18.1 23.0 0.0029 17.3 23.0 1.3 1 0 0 1 1 1 1 Spt20 family eIF-3_zeta PF05091.12 RKO99295.1 - 0.039 12.9 8.7 0.06 12.3 8.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 RKO99295.1 - 0.27 11.3 10.1 0.55 10.3 10.1 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 RKO99295.1 - 0.31 9.3 15.8 0.59 8.3 15.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 RKO99295.1 - 2.2 7.6 8.5 3.7 6.8 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CPSF100_C PF13299.6 RKO99295.1 - 8.8 6.5 7.8 45 4.2 7.8 2.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf67 PF10255.9 RKO99296.1 - 1.9e-111 372.9 0.0 2.3e-111 372.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 RKO99296.1 - 0.024 14.5 0.0 0.074 12.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99296.1 - 0.028 14.5 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Alpha-E PF04168.12 RKO99296.1 - 0.061 13.1 0.3 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. Stealth_CR4 PF17103.5 RKO99296.1 - 0.15 12.0 1.0 0.44 10.5 1.0 1.8 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Suc_Fer-like PF06999.12 RKO99297.1 - 1.5e-39 135.9 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pam16 PF03656.13 RKO99297.1 - 1.8 8.6 4.0 3.3 7.8 4.0 1.3 1 0 0 1 1 1 0 Pam16 PCI PF01399.27 RKO99299.1 - 0.0025 18.3 0.0 0.097 13.2 0.0 2.9 2 0 0 2 2 2 1 PCI domain Zip PF02535.22 RKO99300.1 - 7.9e-45 153.5 21.6 4.5e-43 147.7 21.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3302 PF11742.8 RKO99300.1 - 1.3 9.2 4.5 0.27 11.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) ArgoN PF16486.5 RKO99301.1 - 1.1e-15 58.4 0.0 1.7e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RKO99301.1 - 2.5e-15 55.9 0.1 4.5e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 RKO99301.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Ery_res_leader2 PF08057.11 RKO99301.1 - 0.11 12.9 1.5 0.5 11.0 0.3 2.5 2 0 0 2 2 2 0 Erythromycin resistance leader peptide MBOAT PF03062.19 RKO99302.1 - 7.7e-32 111.0 4.0 9.7e-32 110.7 4.0 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RRN3 PF05327.11 RKO99303.1 - 0.58 8.6 2.4 1 7.8 2.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CAP PF00188.26 RKO99304.1 - 0.002 18.9 0.5 0.4 11.5 0.1 3.2 3 0 0 3 3 3 1 Cysteine-rich secretory protein family DUF4407 PF14362.6 RKO99304.1 - 0.014 14.8 0.4 0.014 14.8 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) LptE PF04390.12 RKO99304.1 - 0.12 13.1 0.8 0.38 11.5 0.7 1.9 1 1 0 1 1 1 0 Lipopolysaccharide-assembly DUF2492 PF10678.9 RKO99304.1 - 0.23 11.8 0.0 0.58 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) ABC_tran PF00005.27 RKO99305.1 - 1.8e-48 164.6 0.0 1.7e-23 83.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 RKO99305.1 - 7.2e-23 80.4 4.2 7.2e-23 80.4 4.2 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 RKO99305.1 - 2.3e-16 60.5 4.4 0.0023 17.8 0.3 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RKO99305.1 - 5.8e-08 32.8 0.0 0.0031 17.3 0.0 2.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 RKO99305.1 - 1.8e-07 30.8 0.1 0.0058 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RKO99305.1 - 2e-07 31.0 1.0 0.0021 18.0 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase SMC_N PF02463.19 RKO99305.1 - 4.6e-07 29.5 1.9 0.41 10.1 0.1 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RKO99305.1 - 1.7e-06 28.4 0.0 0.046 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RKO99305.1 - 2.3e-06 28.0 0.3 0.061 13.7 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_16 PF13191.6 RKO99305.1 - 2.4e-06 28.0 0.0 0.0095 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 RKO99305.1 - 3.1e-06 27.5 0.0 0.051 13.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 RKO99305.1 - 4.9e-06 26.7 0.8 0.11 12.6 0.0 3.8 4 1 0 4 4 3 1 Dynamin family AAA_33 PF13671.6 RKO99305.1 - 6.8e-06 26.3 0.0 0.09 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RKO99305.1 - 2.1e-05 25.2 8.6 0.033 14.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 RKO99305.1 - 2.6e-05 24.8 0.0 0.2 12.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 RKO99305.1 - 3e-05 24.0 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 RKO99305.1 - 3.2e-05 23.7 0.0 0.29 10.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 RKO99305.1 - 4.5e-05 23.5 0.1 0.23 11.6 0.0 3.0 2 1 1 3 3 2 2 50S ribosome-binding GTPase AAA PF00004.29 RKO99305.1 - 0.00031 21.2 0.0 0.93 9.9 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RKO99305.1 - 0.00059 19.5 0.0 2.2 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RKO99305.1 - 0.00079 19.4 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_14 PF13173.6 RKO99305.1 - 0.001 19.1 0.0 2.1 8.4 0.0 3.2 4 1 1 5 5 2 1 AAA domain AAA_5 PF07728.14 RKO99305.1 - 0.0013 18.7 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 RKO99305.1 - 0.0029 16.8 0.0 0.28 10.3 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_27 PF13514.6 RKO99305.1 - 0.0035 17.0 0.0 0.42 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RKO99305.1 - 0.0035 16.9 0.3 1.2 8.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region TsaE PF02367.17 RKO99305.1 - 0.005 16.8 0.1 2 8.5 0.0 2.8 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 RKO99305.1 - 0.0055 15.9 0.1 4.8 6.2 0.0 2.8 2 1 0 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.6 RKO99305.1 - 0.0061 16.3 0.1 0.3 10.8 0.0 2.8 3 1 0 3 3 2 1 AAA domain Roc PF08477.13 RKO99305.1 - 0.0072 16.5 0.0 2.4 8.4 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 RKO99305.1 - 0.011 15.0 0.0 2.8 7.1 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.9 RKO99305.1 - 0.018 14.8 0.2 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 RKO99305.1 - 0.019 14.2 0.0 4 6.6 0.0 2.4 2 0 0 2 2 2 0 Septin dNK PF01712.19 RKO99305.1 - 0.023 14.5 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF815 PF05673.13 RKO99305.1 - 0.024 13.8 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 RKO99305.1 - 0.027 14.6 0.4 6.6 6.7 0.1 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 RKO99305.1 - 0.032 14.0 0.0 3.9 7.2 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MukB PF04310.12 RKO99305.1 - 0.04 13.7 0.0 17 5.1 0.0 3.3 3 0 0 3 3 3 0 MukB N-terminal Arf PF00025.21 RKO99305.1 - 0.053 13.0 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Pox_A32 PF04665.12 RKO99305.1 - 0.059 12.8 0.0 4.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein VPS13_mid_rpt PF16910.5 RKO99305.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Repeating coiled region of VPS13 Zeta_toxin PF06414.12 RKO99305.1 - 0.079 12.2 0.2 1 8.6 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin MeaB PF03308.16 RKO99305.1 - 0.08 11.9 0.0 12 4.8 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 RKO99305.1 - 0.13 12.2 0.1 5.1 7.0 0.1 2.7 2 0 0 2 2 2 0 NTPase DivIC PF04977.15 RKO99305.1 - 2.1 8.2 5.6 4.4 7.2 1.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Zn_clus PF00172.18 RKO99306.1 - 0.0054 16.8 14.2 0.0054 16.8 14.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPP4R2 PF09184.11 RKO99306.1 - 0.12 11.9 5.1 0.19 11.3 5.1 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 RKO99306.1 - 0.36 10.2 4.7 0.65 9.4 4.7 1.3 1 0 0 1 1 1 0 SDA1 Chalcone_2 PF16035.5 RKO99308.1 - 4.2e-11 43.0 0.0 6.8e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Chalcone isomerase like Ribosomal_L12_N PF16320.5 RKO99308.1 - 0.29 10.9 1.4 0.55 10.0 1.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain AA_permease_2 PF13520.6 RKO99309.1 - 1.1e-32 113.4 42.8 1.1e-32 113.4 42.8 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RKO99309.1 - 4.1e-18 65.2 42.6 7.1e-18 64.4 42.6 1.4 1 1 0 1 1 1 1 Amino acid permease F5_F8_type_C PF00754.25 RKO99310.1 - 0.0072 16.4 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain ANAPC10 PF03256.16 RKO99310.1 - 0.067 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) CENP-B_dimeris PF09026.10 RKO99311.1 - 0.016 15.6 7.9 0.14 12.6 0.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CI-B14_5a PF07347.12 RKO99312.1 - 0.0098 15.8 0.9 0.016 15.0 0.9 1.5 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) HECT PF00632.25 RKO99313.1 - 1.3e-96 323.7 0.2 1.6e-96 323.4 0.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 RKO99313.1 - 9.7e-32 108.7 10.3 3.6e-10 39.8 0.9 3.4 3 0 0 3 3 3 3 WW domain C2 PF00168.30 RKO99313.1 - 2.9e-16 59.6 0.1 6e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 C2 domain ParBc_2 PF08857.11 RKO99313.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative ParB-like nuclease WD40 PF00400.32 RKO99314.1 - 4.4e-24 84.3 11.7 1.3e-07 32.2 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99314.1 - 1.7e-06 28.2 0.0 0.29 11.4 0.0 4.8 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ANAPC10 PF03256.16 RKO99315.1 - 1.2e-40 139.1 0.0 1.4e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ery_res_leader2 PF08057.11 RKO99315.1 - 0.17 12.4 0.1 0.65 10.6 0.1 1.9 1 0 0 1 1 1 0 Erythromycin resistance leader peptide OST3_OST6 PF04756.13 RKO99316.1 - 3.9e-69 233.2 0.0 4.3e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PhaG_MnhG_YufB PF03334.14 RKO99316.1 - 0.099 12.9 5.8 0.65 10.3 0.9 2.3 2 0 0 2 2 2 0 Na+/H+ antiporter subunit 7TMR-DISM_7TM PF07695.11 RKO99316.1 - 2.2 8.1 7.2 9.8 6.0 7.2 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling FAD_binding_3 PF01494.19 RKO99317.1 - 6.2e-20 71.7 0.0 1.2e-19 70.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 RKO99317.1 - 0.00047 20.1 0.1 0.00081 19.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 RKO99317.1 - 0.0029 16.7 0.1 0.059 12.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 RKO99317.1 - 0.012 15.9 0.3 0.012 15.9 0.3 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 RKO99317.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 RKO99317.1 - 0.016 14.8 3.3 0.041 13.4 3.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RKO99317.1 - 0.078 12.2 0.1 0.28 10.4 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO99317.1 - 0.16 12.5 0.1 0.35 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L3 PF00297.22 RKO99318.1 - 2e-21 76.4 2.7 5.3e-20 71.7 2.0 2.7 2 1 1 3 3 3 2 Ribosomal protein L3 PspA_IM30 PF04012.12 RKO99319.1 - 0.045 13.3 10.5 0.11 12.1 10.5 1.7 1 0 0 1 1 1 0 PspA/IM30 family AAR2 PF05282.11 RKO99319.1 - 1.4 8.2 5.2 1.7 8.0 4.4 1.5 2 0 0 2 2 2 0 AAR2 protein DUF1822 PF08852.11 RKO99319.1 - 2.1 7.3 8.2 3.5 6.6 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DASH_Spc19 PF08287.11 RKO99319.1 - 5.6 6.8 6.9 0.77 9.6 2.3 2.0 2 0 0 2 2 2 0 Spc19 2OG-FeII_Oxy_2 PF13532.6 RKO99321.1 - 5.9e-37 127.8 0.0 1.7e-36 126.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-C2H2_4 PF13894.6 RKO99322.1 - 2.4e-09 37.2 6.3 0.00012 22.6 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO99322.1 - 3.3e-09 36.7 7.0 4.7e-05 23.6 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RKO99322.1 - 1.4e-05 25.0 1.0 0.025 14.6 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 RKO99322.1 - 0.0004 20.6 0.4 0.00047 20.4 0.4 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RKO99322.1 - 0.0026 18.1 6.6 0.22 12.0 0.2 2.5 2 1 0 2 2 2 2 Zinc-finger double domain zf-LYAR PF08790.11 RKO99322.1 - 0.0035 17.2 1.1 0.11 12.5 0.3 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 RKO99322.1 - 0.0044 17.1 2.7 0.96 9.6 0.2 2.1 2 0 0 2 2 2 2 Zinc ribbon domain Prok-RING_1 PF14446.6 RKO99322.1 - 0.0067 16.3 0.4 3.4 7.7 0.1 2.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 RKO99322.1 - 0.007 16.7 1.1 0.01 16.2 1.1 1.3 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-C2HC5 PF06221.13 RKO99322.1 - 0.0099 15.8 1.2 0.2 11.7 0.1 2.1 1 1 1 2 2 2 1 Putative zinc finger motif, C2HC5-type LIM PF00412.22 RKO99322.1 - 0.01 16.1 1.0 0.011 15.9 1.0 1.1 1 0 0 1 1 1 0 LIM domain Ribosomal_L35p PF01632.19 RKO99322.1 - 0.014 15.9 1.2 0.66 10.5 0.1 2.0 1 1 1 2 2 2 0 Ribosomal protein L35 zf_UBZ PF18439.1 RKO99322.1 - 0.014 15.0 1.0 3.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-FCS PF06467.14 RKO99322.1 - 0.015 15.2 1.1 2 8.4 0.2 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HNH_5 PF14279.6 RKO99322.1 - 0.019 14.8 0.0 0.063 13.2 0.0 1.7 1 1 0 1 1 1 0 HNH endonuclease zf-ribbon_3 PF13248.6 RKO99322.1 - 0.019 14.3 0.7 0.84 9.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 RKO99322.1 - 0.036 14.0 5.9 1.3 9.0 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TF_Zn_Ribbon PF08271.12 RKO99322.1 - 0.044 13.3 0.3 0.1 12.1 0.3 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding zf-C2H2_8 PF15909.5 RKO99322.1 - 0.046 14.0 0.7 0.051 13.9 0.7 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 RKO99322.1 - 0.053 14.2 0.2 0.071 13.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 RKO99322.1 - 0.058 13.9 0.6 1 9.9 0.2 2.7 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 RKO99322.1 - 0.076 13.4 0.2 6.8 7.1 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TFIIS_C PF01096.18 RKO99322.1 - 0.24 11.3 4.7 0.78 9.6 0.8 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CHCC PF10276.9 RKO99322.1 - 0.32 11.1 4.2 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain DUF2256 PF10013.9 RKO99322.1 - 0.52 10.5 5.1 4.2 7.6 1.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 RKO99322.1 - 1 9.4 6.9 2.2 8.3 6.9 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain NDT80_PhoG PF05224.12 RKO99323.1 - 4.9e-20 72.5 0.0 3.6e-19 69.7 0.0 2.5 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family CBF PF03914.17 RKO99324.1 - 1.1e-35 123.1 8.1 1.4e-35 122.8 0.6 3.0 3 0 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 RKO99324.1 - 3.9e-05 23.8 0.2 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKO99324.1 - 0.00037 19.2 0.1 0.00058 18.5 0.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region MMS19_N PF14500.6 RKO99324.1 - 0.057 13.0 0.3 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 RKO99324.1 - 0.19 11.9 2.7 0.31 11.3 0.7 2.3 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Ndc1_Nup PF09531.10 RKO99324.1 - 3.2 6.3 9.0 6 5.4 9.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_sheath_1 PF04984.14 RKO99325.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain DUF3439 PF11921.8 RKO99325.1 - 0.12 12.4 7.7 0.31 11.0 7.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Topoisom_I PF01028.20 RKO99326.1 - 4.5e-88 294.4 1.1 9.5e-88 293.3 1.1 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 RKO99326.1 - 4.4e-83 278.0 0.0 1.4e-82 276.3 0.0 1.8 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 RKO99326.1 - 4e-29 100.3 0.3 8.7e-29 99.3 0.3 1.6 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4115 PF13464.6 RKO99326.1 - 0.052 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) DUF5102 PF17104.5 RKO99326.1 - 0.25 11.3 3.4 0.51 10.3 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) Tubulin PF00091.25 RKO99328.1 - 6.9e-68 228.7 0.0 9.6e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RKO99328.1 - 1.9e-51 173.5 0.0 3e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 RKO99328.1 - 0.00065 19.4 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RhoGEF PF00621.20 RKO99329.1 - 2.2e-26 93.2 0.0 2.7e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 RKO99329.1 - 4.9e-07 30.0 0.1 7.9e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain FKBP_C PF00254.28 RKO99330.1 - 2.8e-27 94.9 0.0 7.5e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 RKO99330.1 - 1.3e-17 64.2 0.0 1.3e-17 64.2 0.0 2.9 2 1 0 2 2 1 1 Nucleoplasmin-like domain YL1 PF05764.13 RKO99330.1 - 1.9e-06 28.2 17.8 2.6e-06 27.7 17.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 RKO99330.1 - 0.14 11.5 32.1 0.22 10.9 32.1 1.2 1 0 0 1 1 1 0 SDA1 POP1 PF06978.11 RKO99330.1 - 0.16 12.0 9.3 0.26 11.2 9.3 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 LAP1C PF05609.12 RKO99330.1 - 0.19 10.7 16.5 0.26 10.3 16.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 RKO99330.1 - 0.56 9.7 15.5 0.74 9.3 15.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop53 PF07767.11 RKO99330.1 - 0.85 8.9 33.3 1.2 8.4 33.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Atg14 PF10186.9 RKO99330.1 - 1 8.4 7.0 1.4 8.0 7.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Band_3_cyto PF07565.13 RKO99330.1 - 1.3 8.8 7.7 1.9 8.2 7.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GREB1 PF15782.5 RKO99330.1 - 2.9 4.9 15.8 3.6 4.6 15.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 RKO99330.1 - 3 7.8 6.5 4.4 7.3 6.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCU PF04678.13 RKO99330.1 - 3.1 7.9 7.4 5.2 7.1 7.4 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter TFIIF_alpha PF05793.12 RKO99330.1 - 5.4 5.5 31.9 7.1 5.1 31.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.13 RKO99330.1 - 6.2 6.3 20.5 8.6 5.9 20.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hamartin PF04388.12 RKO99330.1 - 6.8 5.2 8.7 8.3 4.9 8.7 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 RKO99330.1 - 9 4.8 6.9 13 4.4 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dfp1_Him1_M PF08630.10 RKO99331.1 - 5.3e-15 55.8 0.0 1.1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 RKO99331.1 - 4.2e-12 46.0 0.9 7.9e-12 45.1 0.9 1.5 1 0 0 1 1 1 1 DBF zinc finger RRM_1 PF00076.22 RKO99332.1 - 2.2e-22 78.6 0.0 2.6e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO99332.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 RKO99332.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 RKO99332.1 - 0.16 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4588 PF15251.6 RKO99333.1 - 4e-06 26.8 0.8 1.2e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) RNA_pol_L_2 PF13656.6 RKO99334.1 - 5.7e-27 93.3 0.1 7.3e-27 93.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RKO99334.1 - 2.8e-09 36.3 0.1 4e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ytp1 PF10355.9 RKO99335.1 - 1.7e-30 106.2 0.1 2.8e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF4604 PF15377.6 RKO99335.1 - 2.2e-10 41.2 1.8 3.3e-10 40.6 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Ribosomal_60s PF00428.19 RKO99335.1 - 0.097 13.3 0.6 0.097 13.3 0.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF420 PF04238.12 RKO99335.1 - 0.66 10.3 3.6 0.35 11.2 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF2165 PF09933.9 RKO99335.1 - 3.8 7.5 7.8 43 4.1 0.1 3.2 3 0 0 3 3 3 0 Predicted small integral membrane protein (DUF2165) Serinc PF03348.15 RKO99336.1 - 2.5e-83 280.4 30.0 1.4e-80 271.3 30.0 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF3043 PF11241.8 RKO99336.1 - 0.016 15.3 0.6 0.033 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MAS20 PF02064.15 RKO99337.1 - 1.8e-29 102.5 1.9 8.2e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 MAS20 protein import receptor TPR_1 PF00515.28 RKO99337.1 - 0.014 15.2 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Cyclin_C PF02984.19 RKO99337.1 - 0.036 14.2 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain FUSC PF04632.12 RKO99337.1 - 0.075 11.6 5.1 0.11 11.0 5.1 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family Suc_Fer-like PF06999.12 RKO99338.1 - 3.2e-40 138.1 0.0 4.3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.25 RKO99339.1 - 1.5e-58 198.2 0.0 1.7e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99339.1 - 4.5e-29 101.5 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO99339.1 - 3.3e-09 36.5 0.0 4.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO99339.1 - 0.00064 18.6 0.1 0.001 18.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKO99339.1 - 0.0047 16.9 0.6 0.0095 15.9 0.4 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKO99339.1 - 0.088 11.7 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RKO99339.1 - 0.12 11.7 0.9 0.22 10.8 0.9 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M28 PF04389.17 RKO99340.1 - 3.5e-32 111.7 0.0 8.4e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 RKO99340.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Oxidored_q2 PF00420.24 RKO99340.1 - 0.14 11.8 0.8 0.66 9.6 0.8 2.1 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CoA_binding_3 PF13727.6 RKO99340.1 - 0.28 11.2 3.6 0.74 9.8 3.6 1.7 1 0 0 1 1 1 0 CoA-binding domain Zip PF02535.22 RKO99341.1 - 6.9e-21 74.8 25.2 3.1e-16 59.5 25.2 3.5 1 1 0 1 1 1 1 ZIP Zinc transporter Ribosomal_L27 PF01016.19 RKO99342.1 - 8.4e-31 105.8 0.2 9.3e-31 105.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Rab3-GTPase_cat PF13890.6 RKO99343.1 - 2.3e-35 121.6 1.0 5.1e-27 94.5 0.1 2.4 2 0 0 2 2 2 2 Rab3 GTPase-activating protein catalytic subunit SANT_DAMP1_like PF16282.5 RKO99344.1 - 2.3e-09 37.3 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ribosomal_S15 PF00312.22 RKO99345.1 - 6.8e-16 58.3 0.3 1.3e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 MCM PF00493.23 RKO99346.1 - 6.1e-102 339.5 0.4 4.5e-101 336.6 0.0 2.4 3 0 0 3 3 3 1 MCM P-loop domain MCM_OB PF17207.3 RKO99346.1 - 3.2e-34 117.5 0.9 7.7e-34 116.3 0.9 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKO99346.1 - 1.2e-25 89.7 3.3 3.5e-25 88.2 3.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RKO99346.1 - 3.8e-19 69.2 1.1 3.8e-19 69.2 1.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 RKO99346.1 - 1.1e-06 28.1 0.1 0.00021 20.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKO99346.1 - 8.9e-06 25.7 0.2 0.0002 21.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RKO99346.1 - 0.0002 21.2 0.2 0.00093 19.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RKO99346.1 - 0.019 14.7 0.0 0.7 9.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Complex1_LYR PF05347.15 RKO99347.1 - 1.5e-11 44.2 0.3 2e-11 43.8 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1087 PF06465.13 RKO99347.1 - 0.55 10.3 3.5 0.36 10.9 1.1 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1087) B56 PF01603.20 RKO99348.1 - 4.5e-191 635.3 3.1 5.1e-191 635.1 3.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) NAD1 PF18778.1 RKO99348.1 - 0.091 12.8 0.1 3 7.9 0.1 2.3 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Sec16_C PF12931.7 RKO99351.1 - 1.7e-29 103.4 0.0 2.8e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 RKO99351.1 - 5.3e-08 33.5 0.0 1.5e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.7 RKO99351.1 - 0.00041 20.3 1.3 0.00092 19.2 1.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 RKO99351.1 - 0.0012 18.5 4.3 0.0021 17.7 4.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 RKO99351.1 - 0.0016 17.8 3.3 0.003 16.9 3.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain Cwf_Cwc_15 PF04889.12 RKO99351.1 - 0.053 13.2 4.8 0.12 12.1 4.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IQ PF00612.27 RKO99351.1 - 0.077 12.8 1.8 0.2 11.5 1.8 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif CENP-B_dimeris PF09026.10 RKO99351.1 - 2.3 8.7 9.3 5.4 7.5 9.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 RKO99351.1 - 3.5 8.0 12.2 9 6.7 10.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin PF00225.23 RKO99354.1 - 4.7e-85 285.5 0.0 5.7e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO99354.1 - 1.2e-16 60.9 0.0 3.6e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 RKO99354.1 - 0.22 11.0 0.1 0.93 9.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region PMI_typeI PF01238.21 RKO99355.1 - 9.8e-116 387.0 0.0 1.1e-115 386.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 RKO99355.1 - 4.7e-05 23.0 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 RKO99355.1 - 0.013 15.2 3.2 8.4 6.1 0.1 3.6 4 0 0 4 4 4 0 Cupin Gln-synt_C PF00120.24 RKO99356.1 - 4e-80 269.4 0.0 5.3e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 RKO99356.1 - 1.5e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 RKO99356.1 - 0.00032 20.4 1.0 0.0039 16.9 1.0 2.3 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain NUDIX PF00293.28 RKO99357.1 - 2.3e-05 24.4 0.1 4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NDT80_PhoG PF05224.12 RKO99358.1 - 1.7e-28 100.1 0.0 5.9e-28 98.3 0.0 2.0 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Homeodomain PF00046.29 RKO99359.1 - 4.1e-13 48.9 0.3 7.9e-13 48.0 0.3 1.5 1 0 0 1 1 1 1 Homeodomain MRP-L20 PF12824.7 RKO99359.1 - 1.2e-05 25.5 7.0 3.4e-05 24.1 7.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.11 RKO99359.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF4211 PF13926.6 RKO99361.1 - 5e-24 85.0 0.0 9.6e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Piwi PF02171.17 RKO99362.1 - 4.9e-79 265.7 0.0 7.9e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 RKO99362.1 - 4.5e-15 56.5 0.0 8.4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RKO99362.1 - 1.8e-14 53.1 0.0 3.9e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 RKO99362.1 - 7.3e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 RKO99362.1 - 6.5e-05 23.1 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 RKO99362.1 - 0.00012 22.3 0.0 0.00051 20.3 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain Pex14_N PF04695.13 RKO99363.1 - 0.62 10.7 5.7 0.34 11.5 0.5 2.2 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region tRNA-synt_2b PF00587.25 RKO99364.1 - 2.5e-30 105.8 0.0 4.5e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RKO99364.1 - 1.1e-16 60.7 0.1 2.7e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 RKO99364.1 - 9.7e-13 48.0 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 RKO99364.1 - 1.1e-10 41.4 0.0 5e-10 39.3 0.0 2.1 3 0 0 3 3 3 1 TGS domain Pkinase PF00069.25 RKO99365.1 - 2.3e-56 191.1 0.0 1.2e-37 129.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99365.1 - 2.4e-23 82.8 0.4 1.6e-16 60.3 0.1 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO99365.1 - 0.00023 20.6 0.4 0.0005 19.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RKO99365.1 - 0.00025 21.0 3.1 0.0054 16.7 0.5 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 RKO99365.1 - 0.018 14.7 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RKO99365.1 - 0.055 12.2 0.1 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF1003 PF06210.11 RKO99365.1 - 1.2 9.2 3.1 2.9 8.0 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Ribosomal_60s PF00428.19 RKO99365.1 - 8.2 7.1 7.7 14 6.4 6.9 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rhodanese PF00581.20 RKO99366.1 - 1.2e-16 61.1 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PI-PLC-X PF00388.19 RKO99368.1 - 7.2e-57 191.1 0.0 1.2e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 RKO99368.1 - 1.1e-25 90.2 0.0 2.6e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 RKO99368.1 - 1.6e-06 28.7 0.0 3.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 RKO99368.1 - 6.8e-05 23.1 0.0 0.00089 19.5 0.0 2.6 2 1 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 RKO99368.1 - 0.00086 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 RKO99368.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.8 1 1 0 1 1 1 0 PH domain ATP-grasp_2 PF08442.10 RKO99369.1 - 1.3e-58 197.9 0.5 1.6e-58 197.7 0.5 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 RKO99369.1 - 1.9e-06 27.5 0.4 2.9e-06 26.9 0.3 1.4 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 RKO99369.1 - 0.0062 16.3 0.2 0.039 13.7 0.1 2.0 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Nro1 PF12753.7 RKO99370.1 - 0.005 15.8 0.0 0.3 10.0 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore complex subunit Nro1 2-oxoacid_dh PF00198.23 RKO99370.1 - 0.021 14.3 0.3 0.042 13.3 0.3 1.5 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) RNase_T PF00929.24 RKO99371.1 - 2.4e-19 70.5 0.0 3.2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 RKO99371.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease Pil1 PF13805.6 RKO99372.1 - 4.7e-29 101.7 3.4 5.9e-29 101.4 3.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF773 PF05600.12 RKO99372.1 - 0.00055 18.8 1.2 0.00067 18.5 1.2 1.1 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 CENP-H PF05837.12 RKO99372.1 - 0.11 12.9 3.8 0.22 12.0 0.6 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 RKO99372.1 - 0.12 12.9 7.7 0.074 13.6 2.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3552 PF12072.8 RKO99372.1 - 0.3 10.5 7.1 0.64 9.4 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) MAD PF05557.13 RKO99372.1 - 0.3 9.4 10.5 1.1 7.6 10.5 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein ABC_tran PF00005.27 RKO99373.1 - 1.3e-50 171.5 0.2 8.7e-28 97.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RKO99373.1 - 1.7e-39 136.1 15.1 1.3e-21 77.5 4.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 RKO99373.1 - 1.5e-07 31.1 0.3 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RKO99373.1 - 5.5e-06 26.4 0.8 0.081 13.0 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 RKO99373.1 - 2.3e-05 24.5 4.8 0.0037 17.4 1.1 2.5 2 0 0 2 2 2 2 Dynamin family SMC_N PF02463.19 RKO99373.1 - 2.9e-05 23.6 9.2 0.75 9.2 0.4 4.2 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RKO99373.1 - 5.5e-05 23.1 9.3 0.24 11.2 0.5 4.2 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RKO99373.1 - 5.7e-05 23.1 0.4 0.12 12.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RKO99373.1 - 0.00013 22.4 0.1 0.095 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 RKO99373.1 - 0.00028 20.0 0.1 0.025 13.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 RKO99373.1 - 0.0005 19.8 1.4 0.07 12.8 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKO99373.1 - 0.0014 18.9 2.8 1.7 8.9 0.3 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 RKO99373.1 - 0.0064 17.0 0.8 2.2 8.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 RKO99373.1 - 0.0076 16.0 0.3 0.035 13.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase MeaB PF03308.16 RKO99373.1 - 0.014 14.4 4.7 0.035 13.1 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RKO99373.1 - 0.023 14.3 1.6 3.5 7.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 RKO99373.1 - 0.025 14.2 0.3 1.8 8.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RKO99373.1 - 0.028 14.2 0.3 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 RKO99373.1 - 0.028 13.9 0.5 0.69 9.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 RKO99373.1 - 0.039 13.3 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 RKO99373.1 - 0.043 14.0 0.5 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 RKO99373.1 - 0.16 11.6 0.2 11 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 RKO99373.1 - 0.18 11.7 2.5 15 5.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 RKO99373.1 - 0.2 11.7 7.8 0.35 10.9 0.8 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 RKO99373.1 - 0.23 10.3 1.6 1.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 RKO99373.1 - 0.23 11.5 0.7 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RKO99373.1 - 0.4 9.8 1.6 6.7 5.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AIG1 PF04548.16 RKO99373.1 - 1.6 8.0 4.0 25 4.1 0.2 3.0 3 0 0 3 3 3 0 AIG1 family LRR_4 PF12799.7 RKO99376.1 - 2.2e-34 116.9 34.4 4.1e-08 33.4 1.6 6.8 2 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO99376.1 - 9.7e-23 79.7 23.9 8.6e-06 25.4 0.8 6.5 4 3 3 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 RKO99376.1 - 4.4e-22 78.4 14.3 3.4e-09 36.4 4.2 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RKO99376.1 - 2.7e-08 33.2 24.5 0.068 13.3 0.1 9.1 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 RKO99376.1 - 0.0043 17.4 21.9 36 5.5 0.0 9.1 7 2 0 7 7 7 1 Leucine Rich Repeat AF-4 PF05110.13 RKO99378.1 - 2.7 6.0 15.4 5.6 4.9 15.4 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4498 PF14926.6 RKO99379.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) NIF PF03031.18 RKO99380.1 - 5.4e-26 91.2 0.0 8.2e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 RKO99380.1 - 0.0024 18.2 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 RKO99380.1 - 0.0048 16.8 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain NAPRTase PF04095.16 RKO99381.1 - 4.6e-46 157.4 0.0 2.8e-45 154.8 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 RKO99381.1 - 5.7e-28 97.8 0.0 9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain GTP_EFTU PF00009.27 RKO99382.1 - 1e-27 97.0 7.1 3.6e-27 95.2 2.8 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RKO99382.1 - 2.3e-18 66.3 0.0 5.1e-16 58.7 0.0 2.8 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 RKO99382.1 - 3.4e-08 33.6 0.1 7.6e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 RKO99382.1 - 0.00031 21.0 0.0 0.028 14.8 0.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 RKO99382.1 - 0.0024 17.6 0.0 0.0097 15.7 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation T2SSM_b PF10741.9 RKO99382.1 - 0.011 15.5 2.3 0.099 12.5 0.4 3.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b FeoB_N PF02421.18 RKO99382.1 - 0.031 13.8 0.1 0.12 11.9 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 RKO99382.1 - 0.11 12.5 0.4 7.7 6.5 0.0 2.8 2 1 1 3 3 3 0 Dynamin family DAGK_cat PF00781.24 RKO99382.1 - 1.9 8.1 4.5 12 5.6 0.1 3.6 4 0 0 4 4 4 0 Diacylglycerol kinase catalytic domain Rad51 PF08423.11 RKO99383.1 - 9.9e-14 51.2 0.0 7.8e-06 25.3 0.1 3.6 4 0 0 4 4 4 2 Rad51 AAA_25 PF13481.6 RKO99383.1 - 1.4e-05 24.8 1.2 0.00015 21.4 1.2 2.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 RKO99383.1 - 0.001 18.5 0.1 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 RKO99383.1 - 0.06 13.5 0.2 0.24 11.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain RecA PF00154.21 RKO99383.1 - 0.21 11.0 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein CTP_transf_like PF01467.26 RKO99384.1 - 2.9e-42 144.2 0.1 3.6e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 RKO99384.1 - 4.2e-06 26.7 2.3 0.014 15.3 0.2 2.6 2 0 0 2 2 2 2 FAD synthetase Hydrolase_6 PF13344.6 RKO99385.1 - 2.1e-27 95.2 0.0 4.2e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RKO99385.1 - 8.5e-20 70.6 0.0 2.9e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 RKO99385.1 - 2.8e-11 44.1 0.0 8.6e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RKO99385.1 - 1.1e-06 28.9 0.0 0.00011 22.3 0.0 2.5 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 RKO99385.1 - 0.037 13.6 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Cornichon PF03311.14 RKO99386.1 - 7.6e-51 171.5 8.6 8.7e-51 171.4 8.6 1.0 1 0 0 1 1 1 1 Cornichon protein RasGAP PF00616.19 RKO99389.1 - 2.7e-33 115.4 0.0 4.2e-18 65.8 0.0 2.2 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase LIM PF00412.22 RKO99389.1 - 5.1e-30 103.5 47.7 6.7e-10 39.1 4.1 5.1 5 0 0 5 5 5 4 LIM domain C2 PF00168.30 RKO99389.1 - 1.6e-16 60.5 0.0 3.8e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain C1_1 PF00130.22 RKO99389.1 - 4.1e-05 23.4 11.1 4.1e-05 23.4 11.1 5.7 5 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 RKO99389.1 - 0.0077 16.5 5.2 0.0077 16.5 5.2 5.6 5 2 1 6 6 6 1 C1 domain DUF1077 PF06417.12 RKO99390.1 - 2.5e-44 150.1 0.6 3e-44 149.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Meckelin PF09773.9 RKO99391.1 - 5.7e-56 190.1 0.0 3.3e-42 144.6 0.0 2.1 2 0 0 2 2 2 2 Meckelin (Transmembrane protein 67) tRNA-synt_1g PF09334.11 RKO99392.1 - 1.2e-143 478.6 0.0 1.6e-143 478.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 RKO99392.1 - 4.3e-12 46.0 8.1 1e-11 44.8 8.1 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 RKO99392.1 - 1.2e-05 23.8 0.0 0.0051 15.1 0.0 3.2 4 0 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) SET PF00856.28 RKO99393.1 - 1.5e-21 77.5 0.9 2.7e-20 73.4 0.9 2.3 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 RKO99393.1 - 2e-12 47.6 0.2 1.8e-07 31.5 0.1 2.2 1 1 1 2 2 2 2 COMPASS (Complex proteins associated with Set1p) component N P21-Arc PF04062.14 RKO99395.1 - 2e-76 255.9 0.0 2.4e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CytB6-F_Fe-S PF08802.10 RKO99395.1 - 0.073 13.1 0.1 0.98 9.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit ABC_tran PF00005.27 RKO99396.1 - 6e-27 94.8 0.0 1.4e-26 93.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RKO99396.1 - 0.00062 19.3 0.3 0.0053 16.2 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RKO99396.1 - 0.0009 19.1 0.2 0.24 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 RKO99396.1 - 0.023 15.1 0.1 7 7.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 RKO99396.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 RKO99396.1 - 0.11 12.8 0.7 0.24 11.8 0.7 2.0 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 RKO99396.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Na_H_Exchanger PF00999.21 RKO99397.1 - 3.1e-44 151.3 28.9 4e-44 151.0 28.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3098 PF11297.8 RKO99397.1 - 0.27 10.8 6.6 0.62 9.7 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) DUF2373 PF10180.9 RKO99398.1 - 2.7e-11 43.1 0.0 4.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DHC_N1 PF08385.12 RKO99399.1 - 5.1e-165 550.3 11.6 5.1e-165 550.3 11.6 3.3 2 1 1 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RKO99399.1 - 8.4e-145 481.8 0.0 2.9e-143 476.8 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKO99399.1 - 1.2e-121 406.6 6.0 1.2e-121 406.6 6.0 3.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKO99399.1 - 3.5e-97 325.3 1.1 1.8e-96 323.0 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKO99399.1 - 5.6e-97 324.1 0.0 1.4e-96 322.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKO99399.1 - 2.3e-82 275.4 1.1 2.3e-82 275.4 1.1 3.3 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKO99399.1 - 1.3e-70 236.6 0.2 6.7e-64 214.7 0.0 4.0 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKO99399.1 - 8.3e-55 185.1 0.0 1.8e-54 184.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKO99399.1 - 1.1e-40 138.4 1.0 5.5e-39 132.9 0.1 3.9 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 RKO99399.1 - 1e-37 130.0 4.6 2.1e-37 128.9 4.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 RKO99399.1 - 1.9e-22 79.8 0.0 4.1e-07 30.1 0.0 5.2 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RKO99399.1 - 2.5e-20 72.5 0.0 9.1e-18 64.3 0.0 4.0 3 0 0 3 3 3 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RKO99399.1 - 4.7e-14 52.6 0.0 2.9e-13 50.0 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 RKO99399.1 - 1.4e-10 41.7 2.2 0.29 11.6 0.0 5.5 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKO99399.1 - 2.8e-10 40.9 0.8 0.23 11.8 0.0 6.1 5 1 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 RKO99399.1 - 6.5e-08 32.9 1.2 0.2 11.9 0.0 5.1 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 RKO99399.1 - 1.4e-05 24.3 0.0 0.037 13.1 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 RKO99399.1 - 0.0014 19.2 0.0 3.5 8.2 0.0 4.2 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 RKO99399.1 - 0.013 14.5 0.1 0.052 12.5 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 RKO99399.1 - 0.013 15.3 5.7 1.1 9.0 0.0 3.9 4 0 0 4 4 4 0 AAA domain DUF853 PF05872.12 RKO99399.1 - 0.028 13.0 0.2 0.18 10.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 RKO99399.1 - 0.029 14.5 3.3 18 5.5 0.0 4.8 5 0 0 5 5 4 0 AAA domain AAA_30 PF13604.6 RKO99399.1 - 0.052 13.3 7.9 15 5.2 0.0 5.1 5 0 0 5 5 5 0 AAA domain FtsK_SpoIIIE PF01580.18 RKO99399.1 - 0.076 12.4 0.7 0.3 10.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 RKO99399.1 - 0.13 12.7 0.1 7.6 7.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Acyltransferase PF01553.21 RKO99400.1 - 1.7e-20 73.0 0.0 3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CHCH PF06747.13 RKO99401.1 - 3.5e-05 23.8 4.5 6e-05 23.1 4.5 1.4 1 0 0 1 1 1 1 CHCH domain DUF3128 PF11326.8 RKO99401.1 - 0.053 13.9 2.5 0.26 11.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) BST2 PF16716.5 RKO99401.1 - 0.15 12.7 0.9 0.15 12.7 0.9 1.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CX9C PF16860.5 RKO99401.1 - 0.41 10.7 4.6 8.5 6.5 0.5 2.5 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 RKO99401.1 - 0.49 10.4 5.9 6.7 6.8 5.8 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like mRNA_triPase PF02940.15 RKO99403.1 - 1.6e-29 103.2 0.0 2.2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_26 PF02156.15 RKO99404.1 - 8.9e-09 35.2 0.7 0.00041 19.9 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 Hydrophobin PF01185.18 RKO99405.1 - 2.7e-09 37.5 9.7 4.1e-09 36.9 9.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 RKO99406.1 - 2.4e-10 40.9 9.7 3.3e-10 40.4 9.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin HLH PF00010.26 RKO99407.1 - 9.5e-10 38.3 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.22 RKO99408.1 - 4.3e-07 29.6 0.0 1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKO99408.1 - 1.6e-06 27.7 0.0 5.3e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RKO99408.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 RKO99408.1 - 0.038 14.0 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.21 RKO99408.1 - 0.29 11.3 7.2 0.043 14.0 3.4 1.6 2 0 0 2 2 2 0 FYVE zinc finger ParA PF10609.9 RKO99409.1 - 6.4e-90 300.9 0.0 1.5e-89 299.7 0.0 1.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RKO99409.1 - 8.1e-09 35.6 0.0 1.3e-07 31.8 0.0 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 RKO99409.1 - 1.2e-05 24.9 0.0 0.042 13.3 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 RKO99409.1 - 1.3e-05 25.2 0.0 3.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 RKO99409.1 - 5.8e-05 22.4 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 RKO99409.1 - 0.00069 19.5 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 RKO99409.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 RKO99409.1 - 0.0026 16.8 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 RKO99409.1 - 0.013 15.0 0.0 0.053 13.0 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 RKO99409.1 - 0.026 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 RKO99409.1 - 0.039 14.3 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 RKO99409.1 - 0.054 13.9 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 RKO99409.1 - 0.073 13.1 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SNF2_N PF00176.23 RKO99410.1 - 5.6e-51 173.3 0.0 3.2e-43 147.8 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO99410.1 - 1.4e-13 51.1 0.0 6.8e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKO99410.1 - 2e-08 34.2 0.0 6.6e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO99410.1 - 1.4e-06 28.5 0.0 5.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 RKO99410.1 - 5.1e-06 26.3 10.1 5.1e-06 26.3 10.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKO99410.1 - 2e-05 24.3 9.4 2e-05 24.3 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HDA2-3 PF11496.8 RKO99410.1 - 0.00014 21.1 0.2 0.06 12.5 0.0 2.6 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 zf-RING_5 PF14634.6 RKO99410.1 - 0.0002 21.3 9.8 0.0002 21.3 9.8 2.3 2 1 1 3 3 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RKO99410.1 - 0.0011 18.8 8.7 0.0011 18.8 8.7 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO99410.1 - 0.0017 18.7 8.7 0.0017 18.7 8.7 2.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RKO99410.1 - 0.0022 18.0 7.7 0.0022 18.0 7.7 2.7 3 1 0 3 3 2 1 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 RKO99410.1 - 0.73 9.9 13.8 0.75 9.9 3.9 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain Prok-RING_4 PF14447.6 RKO99410.1 - 4.6 7.2 16.9 0.025 14.5 7.8 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 ATP12 PF07542.11 RKO99412.1 - 1.6e-32 112.3 0.0 2.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein Complex1_LYR PF05347.15 RKO99413.1 - 0.81 9.8 3.5 1.7 8.8 1.3 2.4 2 1 0 2 2 2 0 Complex 1 protein (LYR family) RabGAP-TBC PF00566.18 RKO99414.1 - 4.5e-22 78.8 0.0 6.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 RKO99414.1 - 0.00031 21.2 0.0 0.0007 20.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Gpi1 PF05024.15 RKO99415.1 - 1.1e-63 214.8 9.7 1.7e-63 214.1 9.7 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.25 RKO99416.1 - 4.6e-78 262.2 0.0 5.3e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99416.1 - 7.4e-35 120.5 0.0 9.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO99416.1 - 1.9e-05 24.1 0.1 2.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO99416.1 - 0.00016 20.6 0.0 0.00067 18.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RKO99416.1 - 0.00074 18.9 0.0 0.0019 17.6 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 RKO99416.1 - 0.14 12.1 0.0 1.8 8.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tubulin_C PF03953.17 RKO99417.1 - 2.4e-23 82.7 0.1 3.2e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Pkinase PF00069.25 RKO99418.1 - 2.3e-43 148.5 0.0 2.9e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99418.1 - 3e-28 98.8 0.0 3.8e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 RKO99418.1 - 0.059 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain Dcc1 PF09724.9 RKO99419.1 - 4.1e-47 161.1 0.0 5.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 CAP_N PF01213.19 RKO99419.1 - 2.1 7.7 3.5 3.2 7.2 3.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mcp5_PH PF12814.7 RKO99420.1 - 6.7e-15 55.3 0.3 1.2e-14 54.5 0.3 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology HAP1_N PF04849.13 RKO99420.1 - 0.0062 15.8 2.2 0.0062 15.8 2.2 3.3 2 1 1 3 3 3 1 HAP1 N-terminal conserved region DUF4482 PF14818.6 RKO99420.1 - 0.45 11.4 26.4 0.97 10.3 6.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Nup88 PF10168.9 RKO99420.1 - 5.4 4.7 19.2 8.1 4.1 19.2 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF3482 PF11981.8 RKO99421.1 - 0.034 13.5 0.9 0.059 12.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Methyltransf_11 PF08241.12 RKO99422.1 - 8.7e-10 39.1 0.0 1.9e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 RKO99422.1 - 4e-09 37.1 0.6 6.8e-09 36.4 0.6 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 RKO99422.1 - 1.7e-08 35.0 0.0 3.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO99422.1 - 1.1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO99422.1 - 0.0032 17.3 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO99422.1 - 0.027 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 RKO99422.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 RKO99422.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S13 PF00416.22 RKO99423.1 - 5.3e-18 65.6 0.2 5.8e-16 59.1 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 DNA_pol_lambd_f PF10391.9 RKO99423.1 - 0.03 14.2 0.0 0.29 11.0 0.0 2.4 2 1 0 2 2 2 0 Fingers domain of DNA polymerase lambda FbpA PF05833.11 RKO99423.1 - 0.034 12.9 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_5 PF14520.6 RKO99423.1 - 0.039 14.6 0.0 0.11 13.1 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain gag_pre-integrs PF13976.6 RKO99423.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 GAG-pre-integrase domain CLU PF13236.6 RKO99424.1 - 5.5e-70 235.6 0.0 7.6e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 RKO99424.1 - 6.4e-34 117.5 0.0 1.1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 RKO99424.1 - 4e-10 39.8 6.0 8.9e-05 22.7 1.5 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 RKO99424.1 - 2.4e-09 36.7 8.9 0.034 14.0 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat DUF727 PF05303.12 RKO99424.1 - 0.00016 21.7 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 RKO99424.1 - 0.086 13.0 1.3 7.2 7.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Mg_trans_NIPA PF05653.14 RKO99425.1 - 1.6e-87 293.4 27.1 1.9e-87 293.1 27.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RKO99425.1 - 3.6e-06 27.2 40.4 1.1e-05 25.6 5.9 4.2 1 1 3 4 4 4 4 EamA-like transporter family Prefoldin_2 PF01920.20 RKO99426.1 - 1.1e-20 73.6 0.8 1.2e-20 73.4 0.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Methyltransf_11 PF08241.12 RKO99427.1 - 5.6e-13 49.4 0.0 1.4e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO99427.1 - 3.4e-10 40.5 0.0 8.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO99427.1 - 3.5e-10 40.5 0.0 9.1e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO99427.1 - 1.1e-09 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO99427.1 - 0.00038 20.3 0.0 0.0016 18.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF5522 PF17653.1 RKO99428.1 - 3.2e-18 65.4 2.6 5.6e-18 64.6 2.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Pkinase_Tyr PF07714.17 RKO99429.1 - 2.1e-45 155.1 0.0 2.6e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RKO99429.1 - 5.6e-41 140.7 0.0 7e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain BPL_N PF09825.9 RKO99429.1 - 0.032 13.3 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Amastin PF07344.11 RKO99430.1 - 0.17 11.8 14.2 0.027 14.3 10.1 1.6 2 0 0 2 2 2 0 Amastin surface glycoprotein Glycos_transf_4 PF00953.21 RKO99430.1 - 0.22 11.5 11.7 0.047 13.7 5.4 2.7 2 1 1 3 3 3 0 Glycosyl transferase family 4 AA_kinase PF00696.28 RKO99431.1 - 1.5e-41 142.6 0.7 2.7e-41 141.7 0.2 1.7 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 RKO99431.1 - 1.9e-12 46.7 1.9 1.3e-06 28.0 0.0 3.7 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 RKO99431.1 - 9.6e-11 41.3 2.0 1.1e-07 31.6 0.4 2.8 2 0 0 2 2 2 2 ACT domain ASH PF15780.5 RKO99432.1 - 0.15 12.3 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CtIP_N PF10482.9 RKO99433.1 - 1.5 8.9 8.6 0.62 10.1 0.2 3.0 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain AAA PF00004.29 RKO99434.1 - 2.3e-18 66.9 0.0 5.6e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKO99434.1 - 0.00056 19.9 0.0 0.0057 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IQ PF00612.27 RKO99434.1 - 0.0014 18.2 4.1 0.0014 18.2 4.1 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_18 PF13238.6 RKO99434.1 - 0.0023 18.5 0.7 0.013 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RKO99434.1 - 0.0031 17.9 7.3 0.0036 17.7 0.0 4.2 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 RKO99434.1 - 0.016 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 RKO99434.1 - 0.02 15.1 0.3 0.02 15.1 0.3 3.4 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 RKO99434.1 - 0.028 14.6 0.0 0.028 14.6 0.0 3.1 4 0 0 4 4 4 0 AAA domain ATPase PF06745.13 RKO99434.1 - 0.029 13.7 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC dNK PF01712.19 RKO99434.1 - 0.036 13.9 0.2 3.4 7.5 0.1 2.6 1 1 1 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 RKO99434.1 - 0.054 13.8 3.5 0.19 12.0 0.2 3.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RKO99434.1 - 0.12 12.7 0.6 0.51 10.7 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RKO99434.1 - 0.35 10.4 3.4 3 7.4 0.5 3.6 2 1 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 RKO99434.1 - 0.39 10.4 0.0 0.39 10.4 0.0 2.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 RKO99434.1 - 0.63 10.5 0.0 0.63 10.5 0.0 3.7 4 1 1 5 5 3 0 AAA domain Mannosyl_trans2 PF04188.13 RKO99435.1 - 2.3e-54 185.4 1.6 1.5e-53 182.7 1.6 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) MIIP PF15734.5 RKO99436.1 - 2.6e-09 37.0 0.1 1.8e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Migration and invasion-inhibitory Mito_fiss_reg PF05308.11 RKO99436.1 - 0.55 10.3 9.2 1.2 9.2 9.2 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Sporozoite_P67 PF05642.11 RKO99436.1 - 0.6 8.1 2.3 0.82 7.7 2.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IF3_C PF00707.22 RKO99437.1 - 4.5e-06 26.5 0.0 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 RKO99437.1 - 0.00019 21.7 0.1 0.00034 20.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Angiomotin_C PF12240.8 RKO99437.1 - 0.028 14.0 0.2 0.056 13.0 0.2 1.4 1 0 0 1 1 1 0 Angiomotin C terminal AF-4 PF05110.13 RKO99437.1 - 4.9 5.1 10.8 0.46 8.5 6.2 1.4 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Herpes_capsid PF06112.11 RKO99437.1 - 9.1 6.3 12.8 18 5.4 12.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RRM_1 PF00076.22 RKO99438.1 - 3.5e-19 68.4 0.0 2.8e-08 33.4 0.0 4.5 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 RKO99438.1 - 5.8e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 SPOC domain DUF5092 PF17010.5 RKO99439.1 - 3.7e-24 85.5 0.0 4.1e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5092) PDEase_I PF00233.19 RKO99441.1 - 4.4e-76 255.7 0.2 5.3e-76 255.5 0.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CCDC92 PF14916.6 RKO99442.1 - 0.0095 15.7 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain of unknown function ArfGap PF01412.18 RKO99443.1 - 1e-31 109.4 0.6 1.1e-31 109.3 0.6 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UCH PF00443.29 RKO99444.1 - 1.3e-54 185.5 0.0 1.4e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKO99444.1 - 1e-29 104.1 0.2 4.1e-27 95.6 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 RKO99444.1 - 0.00091 18.8 5.5 0.0031 17.1 2.3 2.8 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Amidoligase_2 PF12224.8 RKO99444.1 - 0.099 12.3 0.6 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 Putative amidoligase enzyme DUF2742 PF10888.8 RKO99445.1 - 0.063 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Calreticulin PF00262.18 RKO99446.1 - 2.1e-124 415.1 0.0 2.4e-124 414.9 0.0 1.0 1 0 0 1 1 1 1 Calreticulin family DUF2613 PF11021.8 RKO99446.1 - 8.4 6.6 16.6 32 4.7 16.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) SBDS PF01172.18 RKO99447.1 - 0.057 13.5 0.1 0.38 10.9 0.1 2.1 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myb_DNA-binding PF00249.31 RKO99448.1 - 4.4e-22 78.0 3.6 7.8e-11 42.0 1.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKO99448.1 - 1e-20 73.7 4.6 3.1e-12 46.6 2.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 RKO99448.1 - 0.011 15.8 0.1 0.54 10.3 0.0 2.6 1 1 1 2 2 2 0 SLIDE HTH_AsnC-type PF13404.6 RKO99448.1 - 0.02 14.7 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rap1_C PF11626.8 RKO99448.1 - 0.027 14.6 0.0 0.28 11.3 0.1 2.3 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 RKO99448.1 - 0.066 13.1 0.0 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Met_synt_B12 PF02965.17 RKO99448.1 - 0.32 10.4 2.2 0.24 10.9 0.1 1.7 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain FAM193_C PF15914.5 RKO99448.1 - 0.73 9.6 2.9 0.96 9.2 1.4 2.0 1 1 1 2 2 2 0 FAM193 family C-terminal SGP PF17228.2 RKO99449.1 - 1.2 10.1 28.5 0.24 12.2 18.8 2.7 2 0 0 2 2 2 0 Sulphur globule protein KRTAP PF11759.8 RKO99449.1 - 1.7 9.3 76.6 1.8 9.1 0.9 3.5 3 1 1 4 4 4 0 Keratin-associated matrix Methyltransf_23 PF13489.6 RKO99451.1 - 7.5e-26 90.9 0.0 9.9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO99451.1 - 2.5e-15 56.9 0.0 4.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO99451.1 - 8.7e-15 55.2 0.0 1.3e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKO99451.1 - 2.5e-14 53.2 0.0 3.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RKO99451.1 - 7e-11 42.1 0.0 8.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO99451.1 - 7.5e-10 39.4 0.0 1.2e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RKO99451.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF3008 PF11450.8 RKO99451.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) Sel1 PF08238.12 RKO99452.1 - 1.4e-07 31.9 6.6 2.4 9.0 0.0 5.8 5 0 0 5 5 5 4 Sel1 repeat DUF4944 PF16302.5 RKO99452.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) adh_short PF00106.25 RKO99454.1 - 2.8e-44 150.9 0.0 3.7e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO99454.1 - 9.9e-35 120.2 0.2 1.2e-34 119.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO99454.1 - 2.5e-09 37.3 0.1 3.6e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO99454.1 - 0.00062 19.3 0.2 0.0016 17.9 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family bZIP_2 PF07716.15 RKO99455.1 - 5.8e-09 35.9 5.1 1.1e-08 35.0 5.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RKO99455.1 - 4.9e-08 32.9 3.3 8e-08 32.3 3.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RKO99455.1 - 0.0054 17.2 4.1 0.0094 16.4 4.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2064 PF09837.9 RKO99455.1 - 0.3 10.9 1.2 0.59 10.0 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Rap_GAP PF02145.15 RKO99456.1 - 2.2e-63 213.2 0.0 2.8e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP AAA PF00004.29 RKO99458.1 - 1.8e-43 148.1 0.0 3.8e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO99458.1 - 4.2e-11 42.5 0.1 1.2e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RKO99458.1 - 3.6e-07 30.5 0.0 1.1e-06 28.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 RKO99458.1 - 6.2e-07 29.3 0.6 1.6e-06 27.9 0.6 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RKO99458.1 - 1.8e-06 28.0 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO99458.1 - 2.7e-06 27.9 0.1 4.6e-05 23.9 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO99458.1 - 6.4e-05 23.2 0.1 0.0093 16.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 RKO99458.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RKO99458.1 - 0.0012 18.1 0.0 0.0028 16.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RKO99458.1 - 0.0013 19.3 0.0 0.022 15.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RKO99458.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RKO99458.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKO99458.1 - 0.003 17.0 0.3 0.021 14.2 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RKO99458.1 - 0.0059 16.5 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RKO99458.1 - 0.0092 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO99458.1 - 0.013 15.9 0.2 0.7 10.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKO99458.1 - 0.013 15.2 0.0 0.1 12.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 RKO99458.1 - 0.018 14.5 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 RKO99458.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RKO99458.1 - 0.024 14.3 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 RKO99458.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 RKO99458.1 - 0.029 13.5 0.2 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RKO99458.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RKO99458.1 - 0.039 14.3 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 RKO99458.1 - 0.042 14.1 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_14 PF13173.6 RKO99458.1 - 0.053 13.6 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4618 PF15397.6 RKO99458.1 - 0.061 12.7 2.2 0.15 11.4 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Parvo_NS1 PF01057.17 RKO99458.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 RKO99458.1 - 0.069 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKO99458.1 - 0.083 12.2 1.1 0.2 10.9 0.0 2.2 3 0 0 3 3 2 0 Zeta toxin APG6_N PF17675.1 RKO99458.1 - 0.1 13.1 2.7 0.21 12.1 2.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_11 PF13086.6 RKO99458.1 - 0.11 12.2 0.2 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RKO99458.1 - 0.13 12.1 0.0 0.64 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain SlyX PF04102.12 RKO99458.1 - 0.21 12.3 2.7 0.9 10.2 2.7 2.1 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 RKO99458.1 - 2.3 8.0 6.0 5.7 6.8 6.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Ig_mannosidase PF17753.1 RKO99459.1 - 2.3e-13 49.7 0.0 5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 RKO99459.1 - 1.6e-07 30.7 0.4 5.4e-07 29.0 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mannosidase_ig PF17786.1 RKO99459.1 - 4.6e-05 23.9 0.6 0.00024 21.7 0.3 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_GlcNase PF18368.1 RKO99459.1 - 0.0002 21.5 0.3 0.0053 16.9 0.0 2.6 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2_N PF02837.18 RKO99459.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain LMBR1 PF04791.16 RKO99460.1 - 2.6e-38 132.2 24.9 8.4e-26 90.9 0.3 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein GPHR_N PF12537.8 RKO99460.1 - 0.25 11.4 1.6 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal UcrQ PF02939.16 RKO99461.1 - 3.7e-15 55.6 0.0 4.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 UcrQ family WD40 PF00400.32 RKO99462.1 - 3.2e-15 56.2 7.3 0.0004 21.1 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99462.1 - 0.0011 19.2 0.0 7.6 6.9 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain EMG1 PF03587.14 RKO99463.1 - 2.8e-80 268.5 0.0 3.3e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PI3_PI4_kinase PF00454.27 RKO99464.1 - 9.3e-33 114.1 0.0 4.9e-32 111.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RKO99464.1 - 9.7e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DDE_Tnp_ISAZ013 PF07592.11 RKO99464.1 - 0.0017 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain CDC24_OB1 PF17246.2 RKO99466.1 - 3.5e-11 43.3 0.0 6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 TFIIS_C PF01096.18 RKO99467.1 - 2.2e-19 69.0 3.1 2.2e-19 69.0 3.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 RKO99467.1 - 2.4e-07 30.5 1.6 2.4e-07 30.5 1.6 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 RKO99467.1 - 0.00012 22.0 7.5 0.023 14.7 1.3 2.6 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 RKO99467.1 - 0.0015 18.2 1.3 0.0015 18.2 1.3 1.8 2 1 0 2 2 1 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_9 PF14369.6 RKO99467.1 - 0.16 12.2 8.8 2.1 8.7 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 RKO99467.1 - 0.24 10.8 0.3 0.24 10.8 0.3 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 RKO99467.1 - 0.46 10.6 8.7 0.41 10.7 3.8 2.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 RKO99467.1 - 0.54 10.1 0.1 0.54 10.1 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-ZPR1 PF03367.13 RKO99467.1 - 0.74 9.7 7.0 0.14 12.1 0.8 2.2 2 1 0 2 2 2 0 ZPR1 zinc-finger domain zinc_ribbon_4 PF13717.6 RKO99467.1 - 1.4 8.9 14.1 12 5.9 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.21 RKO99467.1 - 2 8.7 12.0 6.9e+02 0.6 12.0 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain NYN PF01936.18 RKO99468.1 - 1.8e-12 48.0 0.0 1.4e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 NYN domain SMC_N PF02463.19 RKO99469.1 - 1.5e-59 201.1 0.1 2.1e-59 200.6 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RKO99469.1 - 2.3e-23 82.7 0.0 1.2e-22 80.4 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 RKO99469.1 - 2.1e-12 47.5 0.1 7.1e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RKO99469.1 - 1.2e-08 35.2 0.1 2.4e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RKO99469.1 - 1.2e-07 31.4 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RKO99469.1 - 9.9e-07 29.5 19.7 9.9e-07 29.5 19.7 5.1 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 RKO99469.1 - 0.0014 18.9 0.1 0.025 14.8 0.0 3.2 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 RKO99469.1 - 0.006 17.1 10.8 0.04 14.4 0.0 5.1 4 3 0 4 4 4 1 ABC transporter GMP_synt_C PF00958.22 RKO99469.1 - 0.026 14.6 0.5 0.4 10.8 0.0 3.1 2 1 1 3 3 3 0 GMP synthase C terminal domain HALZ PF02183.18 RKO99469.1 - 2.6 8.3 7.2 6.5 7.1 0.1 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper UTP15_C PF09384.10 RKO99470.1 - 2e-36 124.9 0.6 3.6e-36 124.1 0.6 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 RKO99470.1 - 6e-15 55.4 2.0 0.003 18.4 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99470.1 - 3.8e-06 27.1 0.0 0.13 12.6 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L23 PF00276.20 RKO99471.1 - 2.2e-17 63.2 0.0 2.4e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 MOZ_SAS PF01853.18 RKO99472.1 - 9.2e-40 136.2 0.0 1.1e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RKO99472.1 - 3.8e-14 52.0 1.3 3.8e-14 52.0 1.3 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 RKO99472.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKO99472.1 - 0.098 12.9 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Sec23_trunk PF04811.15 RKO99473.1 - 2.9e-53 181.0 0.0 3.7e-52 177.3 0.0 2.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RKO99473.1 - 4.7e-25 87.4 0.3 8.2e-25 86.6 0.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 RKO99473.1 - 3.2e-13 49.5 3.3 6e-13 48.6 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 RKO99473.1 - 4.5e-13 49.7 0.0 8.2e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 RKO99473.1 - 6.6e-05 22.7 0.0 0.00022 21.1 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat DLH PF01738.18 RKO99474.1 - 1.8e-13 50.5 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Ribosomal_L6 PF00347.23 RKO99475.1 - 2.4e-28 98.6 0.9 8.7e-14 52.0 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 WD40 PF00400.32 RKO99476.1 - 0.01 16.6 0.3 1.9 9.5 0.1 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 RKO99476.1 - 0.26 11.8 0.1 0.26 11.8 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain Sec20 PF03908.13 RKO99477.1 - 1.6e-18 66.4 0.2 2.2e-18 66.0 0.2 1.2 1 0 0 1 1 1 1 Sec20 PBP1_TM PF14812.6 RKO99477.1 - 0.11 12.9 5.9 0.26 11.7 5.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 RKO99477.1 - 0.25 11.0 0.9 0.45 10.2 0.9 1.3 1 0 0 1 1 1 0 FAM176 family MCM2_N PF12619.8 RKO99477.1 - 1.3 9.3 13.2 0.19 12.0 8.8 1.7 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 ER_lumen_recept PF00810.18 RKO99478.1 - 8.7e-50 169.4 4.8 1.2e-49 168.9 4.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 RKO99478.1 - 3.4 7.5 6.9 0.88 9.4 0.2 3.2 4 0 0 4 4 4 0 PQ loop repeat DUF4834 PF16118.5 RKO99479.1 - 0.0012 19.8 8.7 0.0014 19.5 8.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 RKO99479.1 - 0.0017 18.4 19.8 0.0017 18.4 19.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 RKO99479.1 - 0.0022 17.6 29.5 0.0026 17.4 29.5 1.1 1 0 0 1 1 1 1 Spt20 family CobT PF06213.12 RKO99479.1 - 0.0033 16.9 9.4 0.0036 16.7 9.4 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT F-protein PF00469.20 RKO99479.1 - 0.0069 16.0 5.8 0.0077 15.9 5.8 1.1 1 0 0 1 1 1 1 Negative factor, (F-Protein) or Nef DUF4820 PF16091.5 RKO99479.1 - 0.0094 15.3 5.0 0.011 15.1 5.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) Tau95_N PF17682.1 RKO99479.1 - 0.013 15.7 1.3 0.016 15.4 1.3 1.2 1 0 0 1 1 1 0 Tau95 Triple barrel domain RskA PF10099.9 RKO99479.1 - 0.015 15.6 4.7 0.018 15.3 4.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DDHD PF02862.17 RKO99479.1 - 0.019 15.1 4.5 0.018 15.2 4.5 1.1 1 0 0 1 1 1 0 DDHD domain PH_4 PF15404.6 RKO99479.1 - 0.022 14.6 2.8 0.025 14.4 2.8 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain PIP5K PF01504.18 RKO99479.1 - 0.023 13.9 2.6 0.023 14.0 2.6 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AIF_C PF14721.6 RKO99479.1 - 0.032 14.6 4.8 0.04 14.3 4.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Suf PF05843.14 RKO99479.1 - 0.033 14.2 11.2 0.035 14.1 11.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.10 RKO99479.1 - 0.042 12.5 21.9 0.045 12.5 21.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF775 PF05603.12 RKO99479.1 - 0.046 13.2 8.6 0.053 13.1 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Pex14_N PF04695.13 RKO99479.1 - 0.046 14.4 12.2 0.051 14.2 12.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TRM13 PF05206.14 RKO99479.1 - 0.05 13.1 7.9 0.061 12.8 7.9 1.0 1 0 0 1 1 1 0 Methyltransferase TRM13 TERB2 PF15101.6 RKO99479.1 - 0.054 13.5 12.3 0.061 13.4 12.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 RKO99479.1 - 0.061 13.1 5.6 0.068 12.9 5.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SpoIIP PF07454.11 RKO99479.1 - 0.065 12.7 8.7 0.073 12.5 8.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 RKO99479.1 - 0.094 12.9 5.8 0.095 12.9 5.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4746 PF15928.5 RKO99479.1 - 0.094 12.1 4.6 0.11 11.9 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Neur_chan_memb PF02932.16 RKO99479.1 - 0.096 12.7 4.7 0.097 12.7 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 RKO99479.1 - 0.12 10.8 1.5 0.12 10.7 1.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Eapp_C PF10238.9 RKO99479.1 - 0.12 12.4 9.0 0.14 12.2 9.0 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF1980 PF09323.10 RKO99479.1 - 0.12 12.3 2.5 0.13 12.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) EOS1 PF12326.8 RKO99479.1 - 0.13 12.2 1.7 0.13 12.2 1.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 RKO99479.1 - 0.14 10.9 9.8 0.14 10.9 9.8 1.0 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 RKO99479.1 - 0.14 12.6 5.3 0.17 12.2 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Peptidase_U57 PF05582.12 RKO99479.1 - 0.15 11.3 4.5 0.17 11.1 4.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 MDM31_MDM32 PF08118.11 RKO99479.1 - 0.16 10.6 5.0 0.18 10.5 5.0 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins RR_TM4-6 PF06459.12 RKO99479.1 - 0.18 11.6 7.8 0.2 11.5 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN3 PF02487.17 RKO99479.1 - 0.2 10.7 4.5 0.19 10.7 4.5 1.0 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 RKO99479.1 - 0.2 10.6 1.3 0.2 10.6 1.3 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Serinc PF03348.15 RKO99479.1 - 0.21 10.5 2.7 0.23 10.4 2.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.6 RKO99479.1 - 0.23 11.1 5.7 0.28 10.8 5.7 1.1 1 0 0 1 1 1 0 FAM176 family EPL1 PF10513.9 RKO99479.1 - 0.23 11.8 9.6 0.27 11.6 9.6 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4175 PF13779.6 RKO99479.1 - 0.24 9.3 22.4 0.26 9.2 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ureide_permease PF07168.11 RKO99479.1 - 0.26 10.0 2.5 0.28 9.9 2.5 1.0 1 0 0 1 1 1 0 Ureide permease DUF702 PF05142.12 RKO99479.1 - 0.29 11.6 12.4 0.38 11.2 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF2722 PF10846.8 RKO99479.1 - 0.3 10.0 29.6 0.37 9.7 29.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFB6 PF17110.5 RKO99479.1 - 0.3 10.8 5.3 0.38 10.5 5.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH eIF-3_zeta PF05091.12 RKO99479.1 - 0.31 10.0 14.6 0.33 9.9 14.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 RKO99479.1 - 0.33 10.7 6.2 0.37 10.5 6.2 1.1 1 0 0 1 1 1 0 Connexin Pex26 PF07163.12 RKO99479.1 - 0.34 10.2 6.4 0.34 10.2 6.4 1.2 1 0 0 1 1 1 0 Pex26 protein FHIPEP PF00771.20 RKO99479.1 - 0.36 9.2 4.1 0.37 9.2 4.1 1.0 1 0 0 1 1 1 0 FHIPEP family Band_3_cyto PF07565.13 RKO99479.1 - 0.37 10.6 7.7 0.4 10.4 7.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain V_ATPase_I PF01496.19 RKO99479.1 - 0.37 8.7 8.3 0.41 8.5 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3276 PF11680.8 RKO99479.1 - 0.44 10.7 7.9 0.54 10.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Spore_coat_CotO PF14153.6 RKO99479.1 - 0.54 10.2 15.6 0.66 9.9 15.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Folate_carrier PF01770.18 RKO99479.1 - 0.61 8.8 5.2 0.73 8.5 5.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier CBP_BcsG PF11658.8 RKO99479.1 - 0.63 8.4 6.3 0.7 8.2 6.3 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG CDC45 PF02724.14 RKO99479.1 - 0.75 8.0 8.3 0.84 7.9 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein UPF0560 PF10577.9 RKO99479.1 - 0.95 7.9 14.9 1.1 7.7 14.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ALMT PF11744.8 RKO99479.1 - 1 8.1 6.3 1.1 8.0 6.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter OATP PF03137.20 RKO99479.1 - 1.3 7.3 6.3 1.4 7.1 6.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DNApol_Exo PF18136.1 RKO99479.1 - 1.3 8.1 8.5 1.5 7.9 8.5 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Sec62 PF03839.16 RKO99479.1 - 1.3 8.5 6.0 1.5 8.3 6.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2828 PF11443.8 RKO99479.1 - 1.5 6.8 9.4 1.6 6.7 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ctr PF04145.15 RKO99479.1 - 1.6 9.4 6.9 1.8 9.1 6.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Kei1 PF08552.11 RKO99479.1 - 1.9 8.3 4.6 2.1 8.2 4.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3464 PF11947.8 RKO99479.1 - 2 8.2 13.4 2.4 7.9 13.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ndc1_Nup PF09531.10 RKO99479.1 - 2.1 7.0 8.4 2.2 6.9 8.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SprA-related PF12118.8 RKO99479.1 - 2.7 7.1 21.1 2.9 7.0 21.1 1.1 1 0 0 1 1 1 0 SprA-related family PepSY_TM PF03929.16 RKO99479.1 - 2.7 7.6 5.2 2.8 7.5 5.2 1.1 1 0 0 1 1 1 0 PepSY-associated TM region TMEM51 PF15345.6 RKO99479.1 - 2.8 7.7 16.0 3.7 7.3 16.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MDM10 PF12519.8 RKO99479.1 - 3.1 6.6 7.5 3.3 6.5 7.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Hid1 PF12722.7 RKO99479.1 - 3.3 5.7 8.7 3.5 5.6 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4770 PF15994.5 RKO99479.1 - 3.9 7.7 14.4 4.9 7.4 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4407 PF14362.6 RKO99479.1 - 5.2 6.3 13.4 6.4 6.0 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Activator_LAG-3 PF11498.8 RKO99479.1 - 8.1 5.3 35.0 9.3 5.1 35.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4199 PF13858.6 RKO99479.1 - 9.8 6.5 5.5 12 6.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RSN1_7TM PF02714.15 RKO99480.1 - 3.1e-61 207.1 18.4 4.7e-61 206.5 18.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RKO99480.1 - 1.1e-23 84.3 0.1 1.5e-18 67.7 0.0 2.6 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 RKO99480.1 - 1e-18 67.6 0.1 1e-18 67.6 0.1 3.2 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DnaJ PF00226.31 RKO99481.1 - 1.4e-18 66.8 0.9 2.2e-18 66.1 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.24 RKO99482.1 - 2.1e-42 145.2 0.9 9.2e-42 143.1 0.0 2.2 2 1 0 2 2 2 1 Metallopeptidase family M24 TRADD_N PF09034.10 RKO99482.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Serglycin PF04360.12 RKO99484.1 - 0.029 14.3 9.4 0.069 13.1 9.4 1.6 1 0 0 1 1 1 0 Serglycin Hpt PF01627.23 RKO99485.1 - 9.2e-10 38.7 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Hpt domain RIBIOP_C PF04950.12 RKO99486.1 - 1.5e-72 244.5 0.0 2.6e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RKO99486.1 - 6.4e-27 93.5 0.0 1.6e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_33 PF13671.6 RKO99486.1 - 4.3e-06 26.9 0.1 9.4e-05 22.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 RKO99486.1 - 5.7e-05 22.7 0.0 0.0016 18.0 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RKO99486.1 - 0.00023 21.4 0.0 0.00088 19.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RKO99486.1 - 0.0014 18.7 0.2 0.0072 16.4 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 RKO99486.1 - 0.0014 19.1 0.0 0.0014 19.1 0.0 2.9 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 RKO99486.1 - 0.0018 18.8 0.0 0.0066 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKO99486.1 - 0.0032 17.9 0.0 0.0032 17.9 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain cobW PF02492.19 RKO99486.1 - 0.0039 16.8 1.6 0.12 12.0 0.1 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 RKO99486.1 - 0.0058 15.9 1.4 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 RKO99486.1 - 0.0065 16.9 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 RKO99486.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 RKO99486.1 - 0.02 14.0 0.2 0.13 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 RKO99486.1 - 0.023 14.6 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 RKO99486.1 - 0.028 13.7 0.0 0.068 12.4 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 RKO99486.1 - 0.043 14.1 0.5 0.24 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 RKO99486.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 RKO99486.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 RKO99486.1 - 0.086 13.3 0.7 0.32 11.4 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 RKO99486.1 - 0.099 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 RKO99486.1 - 0.18 11.5 0.7 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 RKO99486.1 - 0.8 10.2 6.5 2.7 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain XRCC4 PF06632.12 RKO99487.1 - 4.8 5.9 15.9 5.1 5.9 14.1 1.8 1 1 1 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Abhydrolase_6 PF12697.7 RKO99488.1 - 1.2e-19 71.8 4.9 1.5e-19 71.5 4.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RKO99488.1 - 9.6e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKO99488.1 - 5.2e-08 32.4 0.1 8.5e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 RKO99488.1 - 0.00012 22.3 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 RKO99488.1 - 0.00067 19.6 0.1 0.0014 18.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 RKO99488.1 - 0.0023 17.8 0.6 0.011 15.5 0.1 1.9 1 1 1 2 2 2 1 Serine hydrolase Lipase_3 PF01764.25 RKO99488.1 - 0.0048 16.8 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 RKO99488.1 - 0.0073 15.8 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.13 RKO99488.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 RKO99488.1 - 0.044 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 RKO99488.1 - 0.057 13.2 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 RKO99488.1 - 0.063 12.2 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme BAAT_C PF08840.11 RKO99488.1 - 0.18 11.7 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pox_MCEL PF03291.16 RKO99489.1 - 5.4e-65 219.7 0.0 6.5e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 RKO99489.1 - 9.8e-09 35.8 0.1 1.9e-08 34.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO99489.1 - 0.00075 20.2 0.0 0.002 18.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 RKO99489.1 - 0.00088 18.5 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 RKO99489.1 - 0.0022 18.6 0.0 0.0054 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO99489.1 - 0.019 14.7 0.0 0.063 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Cofilin_ADF PF00241.20 RKO99490.1 - 6.9e-38 129.2 0.3 7.7e-38 129.0 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosom_S12_S23 PF00164.25 RKO99491.1 - 1.2e-47 160.2 0.1 1.7e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 VWA_2 PF13519.6 RKO99492.1 - 1.4e-24 86.8 0.1 5.8e-24 84.8 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 RKO99492.1 - 1.3e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like YjeF_N PF03853.15 RKO99492.1 - 0.015 15.2 0.5 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus EAL PF00563.20 RKO99492.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 EAL domain DUF4362 PF14275.6 RKO99492.1 - 0.14 12.5 0.3 3.9 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4362) AKAP7_RIRII_bdg PF10470.9 RKO99492.1 - 1.4 9.0 4.2 0.31 11.1 0.3 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Pkinase PF00069.25 RKO99493.1 - 8.9e-23 81.0 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99493.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO99493.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Arf PF00025.21 RKO99495.1 - 5.9e-78 260.3 0.1 6.8e-78 260.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RKO99495.1 - 5.5e-14 52.4 0.0 7.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RKO99495.1 - 5.3e-13 48.8 0.0 6.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RKO99495.1 - 5.4e-13 48.8 1.0 4.5e-09 35.9 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RKO99495.1 - 1.7e-12 47.3 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RKO99495.1 - 4.9e-10 39.1 0.0 6.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO99495.1 - 1.5e-05 25.0 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 RKO99495.1 - 0.0092 15.3 0.4 0.024 13.9 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase SIKE PF05769.11 RKO99497.1 - 3.3e-12 46.7 3.8 3.3e-12 46.7 3.8 2.0 2 0 0 2 2 2 1 SIKE family SF-assemblin PF06705.11 RKO99497.1 - 0.059 12.7 1.8 0.1 11.9 1.8 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin AIP3 PF03915.13 RKO99497.1 - 0.094 11.8 0.9 0.13 11.3 0.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 APG17 PF04108.12 RKO99497.1 - 0.097 11.8 7.0 0.17 11.0 5.6 1.8 1 1 1 2 2 2 0 Autophagy protein Apg17 Tropomyosin_1 PF12718.7 RKO99497.1 - 0.1 12.7 5.4 0.17 12.1 1.5 2.2 2 0 0 2 2 2 0 Tropomyosin like Mto2_bdg PF12808.7 RKO99497.1 - 0.13 12.5 2.4 1.5 9.2 0.1 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TACC_C PF05010.14 RKO99497.1 - 0.21 11.4 0.1 0.21 11.4 0.1 2.6 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 RKO99497.1 - 0.25 10.7 5.5 2.2 7.6 0.0 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.6 RKO99497.1 - 0.69 10.1 2.0 24 5.1 0.1 2.8 3 0 0 3 3 3 0 Sperm tail C-terminal domain Sec20 PF03908.13 RKO99497.1 - 1.2 9.2 3.5 6.1 6.8 0.3 2.4 2 1 0 2 2 2 0 Sec20 DUF1178 PF06676.11 RKO99497.1 - 1.7 9.0 9.5 0.15 12.5 4.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) bZIP_2 PF07716.15 RKO99497.1 - 3.2 7.9 10.4 2.6 8.2 0.1 3.6 3 1 0 3 3 3 0 Basic region leucine zipper ParA PF10609.9 RKO99498.1 - 2.1e-88 296.0 0.0 2.3e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RKO99498.1 - 8e-13 48.6 0.0 1.4e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 RKO99498.1 - 5.8e-08 32.5 0.1 1.1e-06 28.3 0.1 2.3 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 RKO99498.1 - 2.4e-07 30.9 0.1 2.6e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 RKO99498.1 - 1.4e-06 27.8 0.4 1.1e-05 24.8 0.4 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 RKO99498.1 - 5.9e-05 22.4 2.4 0.00016 21.0 0.6 2.2 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 RKO99498.1 - 0.0024 17.7 0.4 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 RKO99498.1 - 0.0069 16.0 1.5 0.021 14.4 1.6 1.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 RKO99498.1 - 0.12 12.1 1.8 16 5.1 0.2 2.9 3 0 0 3 3 3 0 AAA domain ubiquitin PF00240.23 RKO99500.1 - 1.8e-25 88.5 0.2 2e-25 88.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RKO99500.1 - 1.6e-13 50.3 0.2 1.8e-13 50.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RKO99500.1 - 0.00044 20.6 0.1 0.0012 19.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 RKO99500.1 - 0.0012 18.7 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 RKO99500.1 - 0.13 12.3 0.3 0.92 9.6 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Proteasome PF00227.26 RKO99501.1 - 7.9e-59 198.3 0.1 9.9e-59 198.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKO99501.1 - 1.5e-13 50.1 0.1 2.9e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1365 PF07103.11 RKO99501.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) Mito_carr PF00153.27 RKO99502.1 - 5.2e-11 42.3 0.7 5e-05 23.1 0.0 5.1 5 0 0 5 5 5 3 Mitochondrial carrier protein Thioredoxin PF00085.20 RKO99503.1 - 1e-12 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RKO99503.1 - 0.012 16.1 0.0 0.017 15.5 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1323 PF07037.11 RKO99503.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) Thioredoxin_8 PF13905.6 RKO99503.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like DnaJ PF00226.31 RKO99504.1 - 1e-17 64.0 1.2 2.2e-17 62.9 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain DDRGK PF09756.9 RKO99504.1 - 1.8 8.1 0.0 1.8 8.1 0.0 2.5 2 1 0 2 2 2 0 DDRGK domain Ank_5 PF13857.6 RKO99505.1 - 4.6e-09 36.4 0.6 1.8e-06 28.1 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKO99505.1 - 5.2e-07 30.2 0.6 0.00029 21.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 RKO99505.1 - 6.6e-07 29.5 0.3 0.0022 18.3 0.2 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RKO99505.1 - 9.4e-06 25.6 3.7 0.18 12.5 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 RKO99505.1 - 0.00075 20.0 0.3 0.19 12.4 0.0 3.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) DNA_pol_phi PF04931.13 RKO99505.1 - 6.1 4.8 10.4 8.8 4.3 10.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Aldedh PF00171.22 RKO99506.1 - 4e-79 266.3 0.0 4.8e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RKO99506.1 - 0.058 12.4 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cyto_heme_lyase PF01265.17 RKO99507.1 - 3.8e-58 197.4 2.7 1.2e-57 195.8 2.7 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2062 PF09835.9 RKO99508.1 - 7.8e-12 45.3 5.8 1.3e-11 44.6 5.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF4203 PF13886.6 RKO99509.1 - 4.1e-26 91.9 22.0 5.1e-26 91.6 22.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2929 PF11151.8 RKO99509.1 - 0.17 12.2 0.3 0.17 12.2 0.3 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2929) Pox_A14 PF05767.12 RKO99509.1 - 0.56 10.4 4.7 2.4 8.4 0.1 3.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Carb_kinase PF01256.17 RKO99510.1 - 8.4e-41 140.0 0.2 2.5e-40 138.5 0.2 1.8 1 1 0 1 1 1 1 Carbohydrate kinase RRM_1 PF00076.22 RKO99511.1 - 3.8e-17 61.9 0.0 6.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3138 PF11336.8 RKO99511.1 - 0.23 10.0 8.3 0.14 10.8 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Caprin-1_C PF12287.8 RKO99511.1 - 4.2 7.4 15.3 0.12 12.4 7.9 1.9 2 0 0 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term DUF1970 PF09301.10 RKO99512.1 - 0.043 14.1 0.1 0.082 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) ADP_PFK_GK PF04587.15 RKO99512.1 - 0.39 9.2 6.1 0.86 8.1 6.1 1.7 1 1 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF844 PF05815.11 RKO99513.1 - 0.47 9.6 3.3 0.51 9.5 3.3 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) GDP_Man_Dehyd PF16363.5 RKO99514.1 - 2.3e-55 188.3 0.0 2e-54 185.2 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RKO99514.1 - 1.5e-47 162.1 0.0 2.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RKO99514.1 - 4.8e-10 38.9 0.0 7.2e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RKO99514.1 - 9.5e-09 34.8 0.1 5.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 RKO99514.1 - 9.5e-09 34.7 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RKO99514.1 - 2.7e-08 33.3 0.0 0.0012 18.0 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 RKO99514.1 - 0.23 10.9 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TBPIP PF07106.13 RKO99515.1 - 6.7e-20 70.8 0.1 1.4e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 RKO99515.1 - 3.5e-12 46.2 0.4 8.8e-12 44.9 0.4 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain HOOK PF05622.12 RKO99515.1 - 0.0018 16.5 1.0 0.0023 16.2 1.0 1.1 1 0 0 1 1 1 1 HOOK protein Penicillinase_R PF03965.16 RKO99515.1 - 0.0091 16.3 0.2 0.057 13.8 0.0 2.2 1 1 2 3 3 3 1 Penicillinase repressor Syntaxin PF00804.25 RKO99515.1 - 0.016 14.9 1.5 0.024 14.3 1.5 1.2 1 0 0 1 1 1 0 Syntaxin DivIC PF04977.15 RKO99515.1 - 0.025 14.3 5.2 0.52 10.1 0.2 2.5 1 1 1 2 2 2 0 Septum formation initiator Surfac_D-trimer PF09006.11 RKO99515.1 - 0.029 14.2 0.0 0.098 12.6 0.0 1.9 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation TMF_DNA_bd PF12329.8 RKO99515.1 - 0.039 13.9 0.9 0.15 12.1 0.9 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 RKO99515.1 - 0.047 13.1 3.6 0.072 12.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1515 PF07439.11 RKO99515.1 - 0.051 13.6 1.0 0.12 12.5 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) GAS PF13851.6 RKO99515.1 - 0.069 12.5 1.5 0.098 12.0 1.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TFIIE_beta PF02186.15 RKO99515.1 - 0.13 12.6 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 TFIIE beta subunit core domain Spc7 PF08317.11 RKO99515.1 - 0.16 10.8 3.0 0.28 10.0 3.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 RKO99515.1 - 0.55 10.7 4.3 13 6.3 1.2 2.3 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 RKO99515.1 - 0.73 10.4 7.2 11 6.6 7.1 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 RKO99515.1 - 7.4 7.1 11.0 1.2e+03 0.0 11.0 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) 2-oxoacid_dh PF00198.23 RKO99516.1 - 9.7e-65 218.3 0.0 1.4e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RKO99516.1 - 3.9e-19 68.3 0.1 6.6e-19 67.5 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RKO99516.1 - 2.2e-13 50.3 0.8 5.5e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 RKO99516.1 - 0.017 14.9 0.1 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like HlyD_D23 PF16576.5 RKO99516.1 - 0.046 12.9 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RINT1_TIP1 PF04437.13 RKO99517.1 - 7.1e-42 143.9 0.0 1.1e-41 143.3 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Spermine_synth PF01564.17 RKO99518.1 - 0.00042 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 RKO99518.1 - 0.012 16.3 0.0 0.029 15.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 RKO99518.1 - 0.02 15.5 0.0 0.046 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 RKO99518.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 RKO99518.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain THDPS_N_2 PF14805.6 RKO99518.1 - 0.23 11.7 1.4 0.49 10.7 1.4 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Band_7 PF01145.25 RKO99519.1 - 3.1e-24 85.9 1.3 4.2e-24 85.5 1.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 RKO99519.1 - 0.0023 17.1 1.4 0.003 16.7 1.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Ribosomal_S30 PF04758.14 RKO99520.1 - 8.8e-24 83.5 4.4 9.7e-24 83.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Got1 PF04178.12 RKO99521.1 - 4.3e-15 56.1 11.4 5.3e-15 55.8 11.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 RKO99521.1 - 1.2 9.5 19.6 0.094 13.1 14.4 1.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) adh_short PF00106.25 RKO99522.1 - 6.9e-33 113.8 3.0 8.4e-33 113.5 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO99522.1 - 1e-20 74.3 5.0 1.2e-20 74.1 5.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO99522.1 - 2.7e-12 47.0 2.0 4.4e-12 46.3 2.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO99522.1 - 1.7e-05 24.5 0.8 2.9e-05 23.7 0.8 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RKO99522.1 - 0.0015 17.8 4.1 0.44 9.7 0.0 2.9 1 1 2 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 RKO99522.1 - 0.047 13.6 3.1 0.079 12.8 3.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding SPT16 PF08644.11 RKO99523.1 - 2.1e-49 167.6 0.0 2.1e-49 167.6 0.0 2.4 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 RKO99523.1 - 2.8e-32 111.8 0.1 1.5e-31 109.4 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 RKO99523.1 - 1.1e-25 90.6 0.0 1.8e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 RKO99523.1 - 2.9e-14 53.2 0.1 7.3e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DOT1 PF08123.13 RKO99524.1 - 3.9e-63 212.7 0.0 4.9e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 RKO99524.1 - 0.00014 21.3 0.2 0.00075 18.9 0.0 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 RKO99524.1 - 0.0088 15.9 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO99524.1 - 0.01 16.5 0.1 0.05 14.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 RKO99524.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RKO99524.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 RKO99524.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NDUFA12 PF05071.16 RKO99525.1 - 5.7e-28 97.6 4.3 6.6e-28 97.4 4.3 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribosomal_L4 PF00573.22 RKO99526.1 - 2.1e-32 112.3 0.1 2.3e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ras PF00071.22 RKO99527.1 - 8.2e-50 168.6 0.0 1.1e-46 158.4 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RKO99527.1 - 3.7e-32 111.1 0.0 5.5e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO99527.1 - 1.7e-11 43.9 0.0 2.5e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKO99527.1 - 3.8e-07 30.2 0.0 8e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKO99527.1 - 3.9e-07 29.8 0.0 1.9e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKO99527.1 - 0.00076 19.4 0.0 0.0038 17.1 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 RKO99527.1 - 0.0011 18.3 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 RKO99527.1 - 0.0033 17.2 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RKO99527.1 - 0.0055 17.1 0.0 0.0078 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO99527.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 RKO99527.1 - 0.033 13.5 0.1 0.061 12.6 0.0 1.4 2 0 0 2 2 2 0 Septin cobW PF02492.19 RKO99527.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 RKO99527.1 - 0.057 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 RKO99527.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 RKO99527.1 - 0.06 13.1 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RKO99527.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RKO99527.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 RKO99527.1 - 0.24 10.5 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 IPK PF03770.16 RKO99528.1 - 1.3e-42 145.9 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase HutP PF09021.11 RKO99529.1 - 0.37 11.1 1.4 0.65 10.3 0.1 2.0 2 1 1 3 3 3 0 HutP PQ-loop PF04193.14 RKO99531.1 - 1.5e-36 124.0 6.2 2.4e-21 75.3 0.6 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 RKO99531.1 - 0.05 13.7 1.3 0.51 10.4 0.2 2.5 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Pterin_4a PF01329.19 RKO99532.1 - 1.2e-29 102.4 0.3 1.3e-29 102.2 0.3 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ETC_C1_NDUFA4 PF04800.12 RKO99532.1 - 0.016 15.5 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 ETC complex I subunit conserved region Cnd1 PF12717.7 RKO99533.1 - 0.00013 22.0 2.6 0.055 13.5 0.0 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RKO99533.1 - 0.034 14.7 1.0 0.034 14.7 1.0 9.8 9 4 2 11 11 11 0 HEAT-like repeat Glycos_transf_N PF04413.16 RKO99533.1 - 0.12 12.0 0.9 0.39 10.4 0.9 1.8 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Kinesin PF00225.23 RKO99534.1 - 9.8e-82 274.5 0.0 1.2e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO99534.1 - 1.3e-20 73.9 0.0 1.9e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding DUF962 PF06127.11 RKO99535.1 - 2.2e-22 78.9 0.9 3.2e-22 78.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF3108 PF11306.8 RKO99536.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) G-patch PF01585.23 RKO99537.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RKO99537.1 - 0.08 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 G-patch domain DinB_2 PF12867.7 RKO99537.1 - 0.15 12.6 0.2 0.15 12.6 0.2 3.1 2 1 0 2 2 2 0 DinB superfamily Borrelia_P83 PF05262.11 RKO99537.1 - 0.6 8.5 12.4 0.85 8.0 12.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Exonuc_V_gamma PF04257.14 RKO99538.1 - 0.099 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit zf-HC5HC2H_2 PF13832.6 RKO99539.1 - 1.3e-10 41.4 4.3 1.3e-10 41.4 4.3 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 RKO99539.1 - 3.6e-09 36.0 10.8 4e-09 35.9 6.1 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 RKO99539.1 - 2.4e-08 33.7 24.0 2.4e-06 27.3 12.2 2.6 2 0 0 2 2 2 2 PHD-finger DUF4694 PF15765.5 RKO99539.1 - 0.0045 17.0 0.7 0.014 15.4 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4694) C1_1 PF00130.22 RKO99539.1 - 0.016 15.1 3.9 0.016 15.1 3.9 3.3 2 2 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RIFIN PF02009.16 RKO99540.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rifin Peptidase_M56 PF05569.11 RKO99540.1 - 0.16 11.1 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 FXR_C1 PF16096.5 RKO99540.1 - 0.21 11.8 3.3 0.7 10.1 3.3 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF3262 PF11660.8 RKO99540.1 - 0.59 10.6 5.9 0.071 13.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) DUF5337 PF17272.2 RKO99540.1 - 0.71 9.7 4.7 6.2 6.7 4.8 2.4 1 1 0 1 1 1 0 Family of unknown function (DUF5337) SKG6 PF08693.10 RKO99540.1 - 1 8.8 7.3 5 6.6 7.3 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_MOT1 PF16983.5 RKO99541.1 - 1.2e-15 57.8 31.9 3.8e-11 43.4 8.3 3.8 5 0 0 5 5 5 2 Molybdate transporter of MFS superfamily ABC_membrane PF00664.23 RKO99542.1 - 1.1e-61 209.0 14.2 5.4e-32 111.5 1.8 3.0 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKO99542.1 - 1.3e-48 165.0 0.0 1.9e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKO99542.1 - 2e-08 34.0 0.0 0.0014 18.1 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 RKO99542.1 - 7.6e-06 26.0 0.7 0.086 12.9 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKO99542.1 - 5.1e-05 23.2 0.1 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 RKO99542.1 - 0.00039 20.1 0.2 0.15 11.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 RKO99542.1 - 0.00043 20.2 0.1 0.15 11.8 0.0 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKO99542.1 - 0.0026 17.5 2.6 1.1 9.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RKO99542.1 - 0.022 15.1 1.9 4.5 7.6 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 RKO99542.1 - 0.044 14.0 0.1 9.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 RKO99542.1 - 0.05 14.1 1.5 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RKO99542.1 - 0.074 13.1 2.4 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 RKO99542.1 - 0.08 13.2 2.0 2.5 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 RKO99542.1 - 0.11 12.0 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 RKO99542.1 - 0.13 12.3 3.2 8.5 6.4 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 RKO99542.1 - 0.15 12.3 1.8 7 7.0 0.1 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ADK PF00406.22 RKO99543.1 - 3.9e-46 156.9 0.0 4.8e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RKO99543.1 - 5.6e-35 120.7 0.0 7.3e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO99543.1 - 8.7e-07 29.5 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 RKO99543.1 - 1.2e-05 25.1 0.1 0.059 13.1 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 RKO99543.1 - 1.2e-05 25.5 0.0 3.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 RKO99543.1 - 0.055 13.1 0.0 0.58 9.8 0.0 2.1 1 1 1 2 2 2 0 Dephospho-CoA kinase LRR_4 PF12799.7 RKO99544.1 - 7.4e-15 54.8 1.5 0.03 14.8 0.0 5.4 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO99544.1 - 4.3e-14 52.0 6.1 0.00041 20.1 0.0 4.9 3 1 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 RKO99544.1 - 6.7e-12 45.3 1.6 1.8e-10 40.6 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 RKO99544.1 - 8.4e-06 25.4 0.0 27 5.2 0.1 6.5 6 0 0 6 6 6 1 Leucine Rich repeat Guanylate_kin PF00625.21 RKO99544.1 - 0.00094 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase LRR_1 PF00560.33 RKO99544.1 - 0.0082 16.6 0.4 1.4e+02 3.7 0.0 5.4 4 2 0 4 4 4 0 Leucine Rich Repeat Methyltransf_31 PF13847.6 RKO99545.1 - 1.2e-09 38.1 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO99545.1 - 5.6e-06 27.0 0.0 1e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO99545.1 - 1.9e-05 25.3 0.1 3.2e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO99545.1 - 3.1e-05 24.5 0.0 6.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FrhB_FdhB_N PF04422.13 RKO99545.1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term NodS PF05401.11 RKO99545.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) AAA_28 PF13521.6 RKO99545.1 - 0.05 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 RKO99545.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 RKO99545.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PIG-F PF06699.11 RKO99546.1 - 1.9e-11 44.4 19.6 5.8e-10 39.6 12.9 2.3 2 0 0 2 2 2 2 GPI biosynthesis protein family Pig-F Lectin_leg-like PF03388.13 RKO99547.1 - 4.4e-68 229.1 0.0 4.8e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RKO99547.1 - 1.2e-06 28.7 0.1 1.5e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 RKO99547.1 - 0.02 14.4 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Legume lectin domain SNF2_N PF00176.23 RKO99548.1 - 1.3e-59 201.7 0.4 1.8e-59 201.2 0.4 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO99548.1 - 3.1e-19 69.3 0.0 5.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO99548.1 - 1.1e-09 38.5 0.0 3.1e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO99548.1 - 2.9e-06 27.2 0.0 8.3e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 RKO99548.1 - 0.0037 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain HDA2-3 PF11496.8 RKO99548.1 - 0.0044 16.2 0.0 13 4.8 0.0 3.1 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 RKO99548.1 - 0.029 14.7 0.1 0.15 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 RKO99548.1 - 0.077 12.6 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Peptidase_C13 PF01650.18 RKO99549.1 - 3.6e-42 144.7 0.0 4.2e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family NUDIX_2 PF13869.6 RKO99550.1 - 3.3e-39 134.4 0.0 3.7e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Zn_clus PF00172.18 RKO99551.1 - 0.0007 19.7 17.3 0.00099 19.2 17.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1658 PF07871.11 RKO99552.1 - 0.042 13.8 1.6 0.042 13.8 1.6 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1658) SR-25 PF10500.9 RKO99552.1 - 0.045 13.3 20.1 0.071 12.7 20.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 RKO99552.1 - 0.22 10.3 4.6 0.25 10.1 4.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3446 PF11928.8 RKO99552.1 - 5.7 7.3 22.4 2 8.7 19.1 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3123 PF11321.8 RKO99552.1 - 8.2 7.1 10.5 1.7 9.4 6.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DNA_binding_1 PF01035.20 RKO99553.1 - 2.1e-19 69.4 0.2 9e-19 67.4 0.2 1.8 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Sec63 PF02889.16 RKO99554.1 - 2.8e-134 446.2 0.0 6.7e-79 264.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RKO99554.1 - 8.7e-36 123.3 0.6 1.9e-23 83.1 0.2 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 RKO99554.1 - 2.1e-18 66.9 0.0 1.4e-14 54.5 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO99554.1 - 7.1e-11 42.4 0.0 2.3e-08 34.4 0.0 3.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RKO99554.1 - 0.00063 20.0 1.0 0.0051 17.1 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 RKO99554.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKO99554.1 - 0.14 11.6 0.0 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region WD40 PF00400.32 RKO99555.1 - 1.5e-46 155.4 13.4 3.8e-07 30.7 0.0 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99555.1 - 1.6e-15 57.2 0.0 0.00041 20.6 0.0 5.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO99555.1 - 2.4e-05 23.4 2.3 0.028 13.4 0.1 3.8 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKO99555.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A FLgD_tudor PF13861.6 RKO99555.1 - 0.021 15.1 0.0 32 4.9 0.0 3.5 3 1 0 3 3 3 0 FlgD Tudor-like domain Trypan_PARP PF05887.11 RKO99557.1 - 0.00026 21.0 7.1 0.00029 20.8 7.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Herpes_LMP1 PF05297.11 RKO99557.1 - 1.9 7.6 17.8 2.1 7.4 17.8 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Neisseria_TspB PF05616.13 RKO99557.1 - 9.7 4.5 13.9 11 4.3 13.9 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-H2C2_2 PF13465.6 RKO99558.1 - 5.5e-12 45.5 9.4 4.1e-06 27.0 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKO99558.1 - 3.9e-11 42.8 11.3 4.3e-06 26.9 2.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO99558.1 - 7.5e-09 35.7 4.9 6.3e-05 23.5 2.1 2.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKO99558.1 - 9e-06 25.4 2.7 0.017 14.8 0.2 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 RKO99558.1 - 0.0033 17.6 0.5 0.039 14.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKO99558.1 - 0.0061 16.5 8.6 0.091 12.8 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-ACC PF17848.1 RKO99558.1 - 0.011 15.8 0.7 5.1 7.3 0.2 2.4 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-H2C2_5 PF13909.6 RKO99558.1 - 0.015 15.1 13.0 0.028 14.2 0.3 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf_UBZ PF18439.1 RKO99558.1 - 0.015 14.8 2.2 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HalOD2 PF18547.1 RKO99558.1 - 0.018 15.0 3.4 0.06 13.3 3.4 1.8 1 1 0 1 1 1 0 Halobacterial output domain 2 Zn-ribbon_8 PF09723.10 RKO99558.1 - 0.02 15.0 3.8 2.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 RKO99558.1 - 0.089 13.3 1.4 2.6 8.6 0.4 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 RKO99558.1 - 0.098 12.8 5.1 0.18 12.0 5.1 1.6 1 1 0 1 1 1 0 FYVE zinc finger zinc_ribbon_4 PF13717.6 RKO99558.1 - 0.11 12.4 4.2 1.6 8.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-LYAR PF08790.11 RKO99558.1 - 0.12 12.3 4.9 3.1 7.8 0.1 2.6 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_5 PF13719.6 RKO99558.1 - 0.12 12.1 6.3 1.8 8.4 6.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 RKO99558.1 - 0.17 11.9 1.5 0.29 11.2 1.5 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Dof PF02701.15 RKO99558.1 - 0.18 12.0 3.1 0.38 10.9 3.1 1.5 1 1 0 1 1 1 0 Dof domain, zinc finger zf-Paramyx-P PF13008.7 RKO99558.1 - 0.18 11.3 4.2 0.69 9.4 0.7 2.1 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein zf-AN1 PF01428.16 RKO99558.1 - 0.18 12.0 7.8 4.6 7.5 3.0 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger C1_4 PF07975.12 RKO99558.1 - 0.23 11.7 4.7 0.62 10.3 3.3 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 RKO99558.1 - 0.36 10.8 7.3 0.51 10.3 7.0 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.6 RKO99558.1 - 0.4 11.4 7.6 0.22 12.2 1.4 2.2 1 1 2 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.11 RKO99558.1 - 0.47 10.4 5.2 6.1 6.8 5.1 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_9 PF14369.6 RKO99558.1 - 0.79 10.0 7.2 1.4 9.3 0.2 2.4 2 1 0 2 2 2 0 zinc-ribbon TRAF6_Z2 PF18048.1 RKO99558.1 - 0.88 9.7 8.6 1.6 8.9 0.2 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 PriA_CRR PF18319.1 RKO99558.1 - 3.3 7.8 11.1 0.7 9.9 0.4 3.1 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain QueC PF06508.13 RKO99558.1 - 5 6.6 5.7 7.3 6.0 0.4 2.0 1 1 1 2 2 2 0 Queuosine biosynthesis protein QueC PAS PF00989.25 RKO99559.1 - 3.7e-09 36.6 0.0 7.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 RKO99559.1 - 1.2e-06 28.7 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 RKO99559.1 - 0.00017 21.8 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 RKO99559.1 - 0.0002 21.6 0.0 0.0002 21.6 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 RKO99559.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain UQ_con PF00179.26 RKO99560.1 - 1.3e-13 50.8 0.0 1.4e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKO99560.1 - 0.062 13.6 0.0 0.073 13.4 0.0 1.1 1 0 0 1 1 1 0 RWD domain Ribosomal_60s PF00428.19 RKO99561.1 - 0.078 13.6 9.5 0.12 12.9 9.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.12 RKO99561.1 - 0.84 8.9 4.0 1.1 8.5 4.0 1.1 1 0 0 1 1 1 0 NOA36 protein Cyclin_N PF00134.23 RKO99562.1 - 0.22 11.2 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain PRP38_assoc PF12871.7 RKO99562.1 - 1.1 9.9 41.3 0.035 14.7 20.6 2.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Serglycin PF04360.12 RKO99563.1 - 0.0066 16.4 7.2 0.017 15.1 7.2 1.6 1 0 0 1 1 1 1 Serglycin NAD_binding_8 PF13450.6 RKO99564.1 - 0.0051 17.0 0.2 0.045 14.0 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HCV_NS4a PF01006.20 RKO99564.1 - 7.9 6.3 10.0 0.35 10.7 2.8 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a NDK PF00334.19 RKO99565.1 - 1e-52 177.7 0.0 1.2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase peroxidase PF00141.23 RKO99566.1 - 4.5e-45 154.1 0.0 6.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase RTA1 PF04479.13 RKO99567.1 - 5.5e-41 140.5 10.0 8.3e-41 139.9 10.0 1.2 1 0 0 1 1 1 1 RTA1 like protein La PF05383.17 RKO99568.1 - 1.8e-14 53.5 0.0 4.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 La domain RNA_pol_Rpc34 PF05158.12 RKO99569.1 - 5.6e-75 252.8 0.1 9.4e-75 252.1 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 RKO99569.1 - 0.001 19.1 0.5 0.47 10.7 0.2 2.3 1 1 1 2 2 2 2 B-block binding subunit of TFIIIC HTH_20 PF12840.7 RKO99569.1 - 0.006 16.6 0.0 2.7 8.1 0.0 2.6 2 1 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 RKO99569.1 - 0.011 15.6 0.1 0.97 9.4 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 RKO99569.1 - 0.018 15.0 0.3 3 7.9 0.1 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Penicillinase_R PF03965.16 RKO99569.1 - 0.036 14.4 1.1 0.68 10.3 0.1 2.8 2 1 1 3 3 3 0 Penicillinase repressor MarR PF01047.22 RKO99569.1 - 0.097 12.6 0.3 4 7.5 0.1 2.5 2 0 0 2 2 2 0 MarR family RPA_C PF08784.11 RKO99569.1 - 0.099 13.3 0.1 0.47 11.2 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal HTH_36 PF13730.6 RKO99569.1 - 0.1 12.6 0.6 1.5 8.8 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain HxlR PF01638.17 RKO99569.1 - 0.12 12.3 0.4 0.94 9.4 0.1 2.2 2 0 0 2 2 2 0 HxlR-like helix-turn-helix DUF2207 PF09972.9 RKO99569.1 - 0.13 11.0 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NTF2 PF02136.20 RKO99570.1 - 3.3e-24 85.8 0.0 5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 RKO99570.1 - 1.6e-05 24.6 0.1 3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TspO_MBR PF03073.15 RKO99571.1 - 2.2e-40 137.9 16.8 2.5e-40 137.7 16.8 1.0 1 0 0 1 1 1 1 TspO/MBR family CcmF_C PF16327.5 RKO99571.1 - 0.063 12.6 4.8 0.082 12.2 4.8 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Isochorismatase PF00857.20 RKO99572.1 - 3.4e-40 138.1 1.0 4.3e-40 137.7 1.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PRIMA1 PF16101.5 RKO99572.1 - 5.1 7.2 7.7 11 6.0 7.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 BPL_LplA_LipB PF03099.19 RKO99573.1 - 1.1e-05 25.4 0.0 2.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family YL1 PF05764.13 RKO99574.1 - 0.011 15.9 2.2 0.016 15.4 2.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF505 PF04458.12 RKO99574.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Filo_glycop PF01611.16 RKO99574.1 - 2.4 7.0 3.3 5 6.0 3.3 1.5 1 0 0 1 1 1 0 Filovirus glycoprotein Kinesin PF00225.23 RKO99575.1 - 2.9e-17 62.6 0.0 9.2e-17 61.0 0.0 1.8 1 1 0 1 1 1 1 Kinesin motor domain DUF4515 PF14988.6 RKO99575.1 - 0.0033 17.3 31.1 0.0033 17.3 31.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) Fungal_TACC PF12709.7 RKO99575.1 - 9.3 6.8 14.5 5.4 7.5 0.0 4.6 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins MFS_1 PF07690.16 RKO99576.1 - 3.2e-38 131.6 67.8 3.5e-27 95.3 44.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF543 PF04418.12 RKO99576.1 - 0.93 9.5 13.4 2.1 8.4 0.5 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF543) Abhydrolase_3 PF07859.13 RKO99578.1 - 6.1e-36 124.3 0.0 7.8e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RKO99578.1 - 3.6e-09 36.0 0.0 4.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 RKO99578.1 - 0.0078 15.1 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 RKO99578.1 - 0.028 13.7 0.0 0.053 12.8 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 RKO99578.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RGS PF00615.19 RKO99579.1 - 4.7e-07 30.1 0.0 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain UQ_con PF00179.26 RKO99581.1 - 4.4e-46 156.0 0.0 4.9e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKO99581.1 - 0.00079 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 RKO99581.1 - 0.0024 17.6 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RKO99581.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 RKO99582.1 - 1.7e-18 66.6 9.0 2e-06 28.4 1.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99582.1 - 4.9e-09 36.4 0.5 0.039 14.2 0.2 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO99582.1 - 4.3e-07 29.0 0.6 0.0035 16.0 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RKO99582.1 - 0.00086 18.7 0.8 0.0067 15.8 0.2 2.1 3 0 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 RKO99582.1 - 0.008 14.7 0.0 0.75 8.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RKO99582.1 - 0.0092 15.0 1.0 1.6 7.6 0.0 3.6 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 RKO99582.1 - 0.023 14.7 0.1 21 5.2 0.0 3.3 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Hc1 PF07432.13 RKO99584.1 - 1.9 8.8 19.1 3.8 7.9 19.1 1.4 1 0 0 1 1 1 0 Histone H1-like protein Hc1 TIP41 PF04176.13 RKO99585.1 - 2.6e-55 186.5 0.0 3.3e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family RcnB PF11776.8 RKO99586.1 - 0.084 12.9 1.3 0.47 10.6 0.3 2.7 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator HLH PF00010.26 RKO99587.1 - 8.8e-19 67.2 0.0 1.5e-18 66.5 0.0 1.4 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hydantoinase_B PF02538.14 RKO99588.1 - 6.1e-205 681.5 1.8 9.1e-205 680.9 1.8 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 RKO99588.1 - 2.2e-90 302.9 0.2 3.6e-90 302.2 0.2 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 RKO99588.1 - 2e-58 197.0 0.0 6.5e-56 188.9 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region UTP25 PF06862.12 RKO99589.1 - 8.6e-144 479.8 0.0 1.1e-143 479.5 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 RKO99589.1 - 0.0006 19.6 0.2 0.19 11.5 0.1 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase DUF502 PF04367.13 RKO99589.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF502) LNS2 PF08235.13 RKO99590.1 - 3.7e-99 330.8 0.0 4.8e-99 330.4 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 RKO99590.1 - 2.6e-39 133.3 0.0 7.1e-39 131.9 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region DUF1064 PF06356.11 RKO99590.1 - 0.2 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) T_cell_tran_alt PF15128.6 RKO99591.1 - 0.91 9.4 2.7 0.83 9.5 0.5 2.1 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Holin_9 PF16936.5 RKO99591.1 - 1.3 9.2 0.0 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 Putative holin Y_phosphatase2 PF03162.13 RKO99592.1 - 9.2e-48 161.9 0.0 1e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKO99592.1 - 1.4e-05 25.1 0.0 1.7e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RKO99592.1 - 0.031 14.1 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO99592.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RKO99592.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate SANT_DAMP1_like PF16282.5 RKO99594.1 - 1.1e-19 70.4 0.1 2.5e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 TPR_1 PF00515.28 RKO99595.1 - 1.2e-09 37.6 11.2 0.0017 18.1 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99595.1 - 1.1e-07 31.4 17.9 0.0027 17.7 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99595.1 - 0.00011 21.7 3.6 0.0074 16.0 0.3 2.8 2 1 0 2 2 2 2 TPR repeat UBA PF00627.31 RKO99595.1 - 0.0051 16.7 0.2 0.014 15.2 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 RKO99595.1 - 0.012 15.8 0.2 0.029 14.5 0.0 1.8 2 0 0 2 2 2 0 DnaJ domain TPR_8 PF13181.6 RKO99595.1 - 0.019 15.2 3.7 6.6 7.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99595.1 - 0.11 12.6 8.4 0.15 12.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99595.1 - 0.28 11.5 17.5 33 4.9 8.8 3.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99595.1 - 0.58 10.7 3.8 0.61 10.6 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 RKO99595.1 - 4.1 7.6 27.4 0.27 11.4 1.2 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat zf-CSL PF05207.13 RKO99596.1 - 2.5e-23 81.6 0.5 2.9e-23 81.3 0.5 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 RKO99596.1 - 0.0018 18.4 0.1 0.0033 17.6 0.1 1.5 1 0 0 1 1 1 1 C4-type zinc ribbon domain Prok-RING_1 PF14446.6 RKO99596.1 - 0.055 13.4 1.0 0.1 12.6 1.0 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf_CCCH_4 PF18345.1 RKO99597.1 - 1.1 9.4 6.4 0.76 9.9 0.9 3.1 3 0 0 3 3 3 0 Zinc finger domain RNA_pol_Rpb1_5 PF04998.17 RKO99598.1 - 9.2e-102 340.0 0.0 1.5e-101 339.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 RKO99598.1 - 5.8e-101 337.9 0.1 9.3e-101 337.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 RKO99598.1 - 1.1e-71 240.4 0.0 2.2e-71 239.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 RKO99598.1 - 3.9e-65 219.3 0.0 1.1e-64 217.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 RKO99598.1 - 2.1e-46 157.7 0.0 8.2e-46 155.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RKO99598.1 - 8e-39 131.9 0.2 1.9e-38 130.7 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 RKO99598.1 - 1.8e-36 125.1 1.6 3.3e-36 124.3 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.13 RKO99598.1 - 5.3e-08 32.8 326.0 0.43 11.0 16.3 15.8 9 2 14 23 23 23 20 RNA polymerase Rpb1 C-terminal repeat zf-C4pol PF14260.6 RKO99598.1 - 0.63 10.5 4.1 1.8 9.1 4.1 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta MIF4G_like PF09088.11 RKO99599.1 - 2.1e-33 115.7 1.5 1.7e-30 106.2 0.4 3.8 3 1 0 3 3 3 1 MIF4G like MIF4G_like_2 PF09090.11 RKO99599.1 - 3.5e-29 102.1 0.0 6.4e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G like AAA_lid_9 PF17871.1 RKO99599.1 - 1.4 8.9 4.9 49 3.9 0.3 3.3 3 0 0 3 3 3 0 AAA lid domain ATP-synt_S1 PF05827.12 RKO99600.1 - 0.0056 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SLATT_1 PF18181.1 RKO99600.1 - 9.7 6.1 8.2 0.2 11.6 0.5 2.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Ras PF00071.22 RKO99601.1 - 1.6e-15 57.1 0.0 6.8e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RKO99601.1 - 0.00021 21.5 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RKO99601.1 - 0.068 12.7 0.1 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CRC_subunit PF08624.10 RKO99602.1 - 2.2e-25 89.7 0.0 2.9e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nse4_C PF08743.10 RKO99603.1 - 4.5e-08 33.3 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 RKO99603.1 - 0.22 11.7 0.0 0.22 11.7 0.0 2.6 3 0 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE Cwf_Cwc_15 PF04889.12 RKO99603.1 - 0.78 9.4 9.1 0.24 11.1 4.4 2.3 2 1 1 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4272 PF14094.6 RKO99604.1 - 0.00037 19.8 0.1 0.00037 19.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4272) GARS_A PF01071.19 RKO99605.1 - 3.1e-73 245.7 0.0 4.6e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 RKO99605.1 - 1.8e-33 115.9 0.0 4.1e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 RKO99605.1 - 8.6e-29 100.2 0.6 2e-28 99.0 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 RKO99605.1 - 4.1e-24 84.7 1.4 1.1e-23 83.3 1.4 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 RKO99605.1 - 1e-11 45.3 9.2 1e-11 45.3 9.2 2.6 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain SUZ PF12752.7 RKO99606.1 - 2e-05 25.2 0.1 2e-05 25.2 0.1 2.3 2 1 0 2 2 2 1 SUZ domain GNAT_acetyltr_2 PF13718.6 RKO99607.1 - 7.2e-79 264.4 0.0 1.4e-78 263.4 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 RKO99607.1 - 7.7e-61 205.0 0.0 4.8e-60 202.4 0.0 2.2 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 RKO99607.1 - 1.2e-43 149.5 3.2 1.4e-42 146.0 3.2 2.2 1 1 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 RKO99607.1 - 2.4e-31 107.5 0.1 6e-31 106.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 RKO99607.1 - 5.7e-05 23.4 0.0 0.00019 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Acetyltransf_1 PF00583.25 RKO99607.1 - 0.011 16.0 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_30 PF13604.6 RKO99607.1 - 0.038 13.7 0.0 0.18 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Acetyltransf_7 PF13508.7 RKO99607.1 - 0.05 14.0 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.6 RKO99607.1 - 0.078 13.3 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DNA_pol_A_exo1 PF01612.20 RKO99609.1 - 7.5e-14 51.8 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Cys_Met_Meta_PP PF01053.20 RKO99610.1 - 7.2e-36 123.5 0.0 9.9e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RKO99610.1 - 0.043 13.0 0.0 0.089 11.9 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II RIC1 PF07064.13 RKO99611.1 - 3.9e-59 200.1 1.8 6.3e-59 199.4 1.8 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 RKO99611.1 - 2.4e-07 31.0 0.1 0.018 15.3 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 RKO99611.1 - 0.034 14.1 0.0 14 5.8 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 RKO99611.1 - 0.11 13.4 0.1 32 5.6 0.0 3.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Hemerythrin PF01814.23 RKO99611.1 - 0.35 11.5 2.3 0.57 10.8 0.5 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain NAD_Gly3P_dh_N PF01210.23 RKO99613.1 - 2.1e-50 170.7 0.0 4.5e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 RKO99613.1 - 1e-44 152.3 0.2 1.7e-44 151.5 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 RKO99613.1 - 0.032 14.8 0.0 16 6.2 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Tic110 PF16940.5 RKO99614.1 - 0.0064 15.0 0.4 0.0064 15.0 0.4 2.1 1 1 1 2 2 2 1 Chloroplast envelope transporter AAA_16 PF13191.6 RKO99615.1 - 8.4e-07 29.5 0.4 8.2e-06 26.3 0.4 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO99615.1 - 1.8e-06 28.2 0.0 4.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RKO99615.1 - 5.7e-06 26.8 0.0 2.3e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 RKO99615.1 - 0.027 14.6 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA lid domain NACHT PF05729.12 RKO99615.1 - 0.031 14.2 0.1 0.47 10.4 0.1 2.4 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 RKO99615.1 - 0.069 13.5 0.6 0.28 11.5 0.1 2.1 3 0 0 3 3 3 0 AAA domain FKBP_C PF00254.28 RKO99616.1 - 0.0019 18.5 0.0 0.0045 17.3 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SH3_1 PF00018.28 RKO99617.1 - 7.8e-13 47.8 0.0 8.9e-13 47.6 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKO99617.1 - 1.3e-10 40.9 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKO99617.1 - 3.9e-09 36.1 0.0 3.9e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 RKO99617.1 - 0.049 13.5 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial SH3 domain GalP_UDP_transf PF01087.22 RKO99618.1 - 9e-55 185.9 0.0 1.4e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 RKO99618.1 - 5.1e-44 149.9 0.0 9.6e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 RKO99618.1 - 3.6e-06 27.6 0.0 0.00035 21.2 0.0 2.6 2 1 0 2 2 2 1 HIT domain DUF4921 PF16268.5 RKO99618.1 - 0.13 11.0 0.4 2.5 6.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) TAFII55_N PF04658.13 RKO99619.1 - 7.2e-38 129.8 0.0 9.2e-37 126.2 0.0 2.3 1 1 0 1 1 1 1 TAFII55 protein conserved region SDA1 PF05285.12 RKO99619.1 - 2.5 7.4 12.8 3.1 7.1 12.8 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 RKO99619.1 - 3 6.3 9.5 3.8 6.0 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 RKO99619.1 - 5.5 5.1 7.9 6.9 4.8 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribonuc_P_40 PF08584.11 RKO99620.1 - 1.3e-29 103.4 0.0 2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Gti1_Pac2 PF09729.9 RKO99621.1 - 1.4e-38 132.8 0.0 5.3e-33 114.6 0.0 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Myb_DNA-binding PF00249.31 RKO99622.1 - 4.2e-39 132.5 0.1 2.4e-15 56.4 0.0 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKO99622.1 - 1.5e-27 95.6 0.0 8.5e-13 48.4 0.0 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 RKO99622.1 - 0.00026 21.0 0.0 0.083 12.9 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 RKO99622.1 - 0.0065 16.3 0.0 1.5 8.8 0.0 2.8 1 1 2 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 RKO99622.1 - 0.0077 16.3 0.0 0.24 11.5 0.0 2.2 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 RKO99622.1 - 0.028 14.8 0.8 0.58 10.6 0.2 3.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 RKO99622.1 - 0.051 13.7 0.8 3.7 7.8 0.1 3.6 2 2 2 4 4 4 0 Rap1 Myb domain Death PF00531.22 RKO99622.1 - 0.088 13.0 0.3 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Death domain RhoGAP PF00620.27 RKO99623.1 - 1.6e-50 170.9 0.0 1.7e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF4218 PF13960.6 RKO99623.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) TAF8_C PF10406.9 RKO99625.1 - 9.7e-10 38.9 3.1 9.7e-10 38.9 3.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 RKO99625.1 - 0.0013 18.7 0.1 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.32 RKO99626.1 - 0.0035 18.1 4.7 3.3 8.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat E1-E2_ATPase PF00122.20 RKO99627.1 - 3.5e-50 170.1 0.2 3.5e-50 170.1 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RKO99627.1 - 1.4e-43 148.7 0.1 3.7e-43 147.4 0.1 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RKO99627.1 - 3.2e-18 66.8 4.7 2.1e-16 60.8 4.7 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKO99627.1 - 8.9e-13 47.7 0.0 2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RKO99627.1 - 5.4e-07 29.6 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKO99627.1 - 0.00077 19.3 1.1 0.0013 18.6 1.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 RKO99628.1 - 7.6e-05 22.5 14.9 7.6e-05 22.5 14.9 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKO99628.1 - 0.017 15.1 16.4 0.017 15.1 16.4 3.4 3 1 0 3 3 3 0 zinc-RING finger domain DUF4509 PF14970.6 RKO99630.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Trehalase PF01204.18 RKO99631.1 - 9.3e-156 519.6 0.0 1.2e-155 519.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 RKO99631.1 - 5.4e-15 54.8 0.2 1e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ECH_2 PF16113.5 RKO99632.1 - 3.3e-113 378.6 0.0 4.2e-113 378.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 RKO99632.1 - 8.1e-31 107.2 0.1 1.5e-30 106.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DHHA2 PF02833.14 RKO99633.1 - 4.7e-23 82.0 0.0 6.6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 RKO99633.1 - 6.3e-08 32.8 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 DHH family C2 PF00168.30 RKO99635.1 - 6.4e-21 74.6 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-CSL PF05207.13 RKO99636.1 - 6.4e-16 57.8 0.0 9.1e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 RKO99636.1 - 7.2e-09 35.7 0.0 5.8e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain zinc_ribbon_4 PF13717.6 RKO99636.1 - 0.035 14.0 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Cwf_Cwc_15 PF04889.12 RKO99636.1 - 0.086 12.6 6.4 0.12 12.1 6.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RKO99636.1 - 0.24 10.7 5.1 0.33 10.2 5.1 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RKO99636.1 - 5.1 7.5 15.2 15 6.1 15.2 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain VASt PF16016.5 RKO99637.1 - 5.2e-24 85.4 0.0 7.8e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 RKO99637.1 - 2.9e-13 49.7 0.0 4.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 GRAM domain KRTAP PF11759.8 RKO99638.1 - 0.046 14.3 6.0 0.089 13.4 6.0 1.3 1 0 0 1 1 1 0 Keratin-associated matrix SelP_N PF04592.14 RKO99638.1 - 0.68 9.3 50.9 2.3 7.6 6.1 3.5 3 0 0 3 3 3 0 Selenoprotein P, N terminal region TPR_19 PF14559.6 RKO99639.1 - 2.5e-11 43.9 51.6 0.0023 18.4 0.3 7.9 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99639.1 - 3.7e-09 36.0 30.7 0.18 12.0 0.2 9.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKO99639.1 - 1.1e-05 25.8 89.0 0.015 16.1 1.4 12.1 6 4 5 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99639.1 - 0.00043 20.9 92.8 0.07 13.8 6.9 8.7 6 2 3 9 9 9 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKO99639.1 - 0.0047 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 RKO99639.1 - 0.013 15.2 11.1 1.2 8.8 0.9 4.9 5 0 0 5 5 5 0 TPR repeat TPR_12 PF13424.6 RKO99639.1 - 0.021 15.1 0.1 0.021 15.1 0.1 7.6 8 2 1 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99639.1 - 0.023 15.0 5.1 0.42 11.1 0.0 5.0 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99639.1 - 0.036 14.3 9.9 4.6 7.7 0.0 5.5 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 RKO99639.1 - 0.068 12.9 0.3 0.068 12.9 0.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 RKO99639.1 - 0.16 11.9 14.6 0.33 10.8 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99639.1 - 0.39 11.5 38.1 4.9 8.0 0.1 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99639.1 - 0.54 10.4 22.9 0.67 10.1 0.5 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO99639.1 - 3.1 8.1 11.3 6.1 7.1 0.3 5.0 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Cpn60_TCP1 PF00118.24 RKO99640.1 - 8.7e-159 529.3 1.3 9.8e-159 529.1 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 RKO99641.1 - 7.6e-73 245.1 0.0 1.1e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99641.1 - 3.6e-48 164.1 0.0 6.4e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RKO99641.1 - 1.8e-19 69.8 0.0 3.5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 RKO99641.1 - 1.2e-12 48.2 0.5 2.3e-12 47.3 0.5 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 RKO99641.1 - 5.7e-08 32.4 0.1 1.3e-07 31.2 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKO99641.1 - 1.5e-05 24.0 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKO99641.1 - 3.7e-05 23.8 0.2 0.012 15.5 1.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKO99641.1 - 4.8e-05 22.5 0.1 8.9e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 RKO99641.1 - 0.00081 19.8 2.0 0.0094 16.4 2.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Seadorna_VP7 PF07387.11 RKO99641.1 - 0.1 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 RKO99641.1 - 0.16 11.6 0.1 0.48 10.0 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RGS PF00615.19 RKO99642.1 - 0.0049 17.1 0.0 0.013 15.8 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain SPRY PF00622.28 RKO99643.1 - 1.4e-07 31.7 0.0 0.00087 19.4 0.0 2.3 2 0 0 2 2 2 2 SPRY domain RrnaAD PF00398.20 RKO99644.1 - 8.9e-61 205.3 0.0 1.1e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RKO99644.1 - 2.9e-07 31.1 0.0 5.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO99644.1 - 6.7e-05 23.5 0.0 0.00012 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RKO99644.1 - 0.00043 20.1 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 RKO99644.1 - 0.00061 19.2 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 RKO99644.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 RKO99644.1 - 0.0032 18.2 0.0 0.0059 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO99644.1 - 0.0033 17.3 0.0 0.0053 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 RKO99644.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.15 RKO99644.1 - 0.059 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 RKO99644.1 - 0.07 12.9 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 RKO99644.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_3 PF01596.17 RKO99644.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_28 PF02636.17 RKO99644.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_L24e PF01246.20 RKO99646.1 - 4.3e-32 110.1 5.5 4.3e-32 110.1 5.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Myb_DNA-binding PF00249.31 RKO99647.1 - 7.1e-06 26.1 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKO99647.1 - 0.038 14.2 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain MRC1 PF09444.10 RKO99648.1 - 7.2e-19 68.8 11.1 7.2e-19 68.8 11.1 6.7 7 0 0 7 7 7 2 MRC1-like domain ECH_1 PF00378.20 RKO99649.1 - 1.7e-85 286.3 0.4 2e-85 286.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKO99649.1 - 3.3e-40 138.6 3.0 7e-36 124.4 1.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 RKO99649.1 - 0.08 12.9 0.4 0.44 10.5 0.0 2.2 3 0 0 3 3 3 0 Peptidase family S49 PH PF00169.29 RKO99650.1 - 0.011 16.3 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 PH domain ApoO PF09769.9 RKO99651.1 - 2.8e-13 49.9 1.0 1.6e-12 47.5 0.0 2.5 2 1 0 2 2 2 1 Apolipoprotein O ubiquitin PF00240.23 RKO99651.1 - 1e-05 25.2 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 RKO99651.1 - 0.17 12.5 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RKO99651.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Myotub-related PF06602.14 RKO99653.1 - 3.3e-108 361.8 0.0 3.7e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RKO99653.1 - 0.0017 18.2 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO99653.1 - 0.0032 17.1 0.1 0.0048 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RKO99653.1 - 0.028 14.4 0.2 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family MBF1 PF08523.10 RKO99654.1 - 6.2e-16 58.6 7.1 1.5e-15 57.4 7.1 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 RKO99654.1 - 5.3e-09 36.0 0.4 5.3e-09 36.0 0.4 1.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 RKO99654.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 RKO99654.1 - 0.032 14.3 0.2 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Kinesin PF00225.23 RKO99655.1 - 3.6e-117 391.0 0.0 4.1e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO99655.1 - 2.1e-29 102.4 0.0 4.9e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF4874 PF16173.5 RKO99656.1 - 6.1e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) SOG2 PF10428.9 RKO99656.1 - 1.2 8.3 13.2 1.6 7.8 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 RKO99656.1 - 1.2 7.1 21.5 1.8 6.6 21.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Adaptin_N PF01602.20 RKO99657.1 - 3.8e-06 25.8 0.3 6.9e-06 24.9 0.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 RKO99657.1 - 0.15 12.4 29.4 0.13 12.7 0.7 5.4 5 1 1 6 6 6 0 HEAT repeats HEAT PF02985.22 RKO99657.1 - 0.35 11.2 0.1 0.35 11.2 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat zf-rbx1 PF12678.7 RKO99658.1 - 3.1e-25 88.2 12.7 4.2e-25 87.8 12.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RKO99658.1 - 3.1e-17 62.4 9.5 3.9e-17 62.1 9.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 RKO99658.1 - 4.4e-07 30.1 13.8 1.8e-05 25.0 13.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RKO99658.1 - 0.00025 20.9 11.7 0.0034 17.2 11.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO99658.1 - 0.0003 20.6 14.2 0.0024 17.7 9.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SCIFF PF13165.6 RKO99658.1 - 0.045 13.7 2.8 0.079 12.9 2.8 1.5 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF zf-RING_11 PF17123.5 RKO99658.1 - 0.074 12.8 14.8 6.9 6.5 14.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 RKO99658.1 - 0.19 11.6 11.0 0.64 9.9 4.7 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO99658.1 - 0.19 11.7 9.3 1.4 9.0 9.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.6 RKO99658.1 - 0.32 11.3 9.4 18 5.7 9.4 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.6 RKO99658.1 - 0.72 10.1 9.0 0.73 10.0 0.8 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 RKO99658.1 - 0.75 9.5 13.8 31 4.3 13.8 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RKO99658.1 - 0.97 9.7 9.7 6.2 7.1 9.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 RKO99658.1 - 2.6 8.1 10.9 26 4.9 10.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain DUF953 PF06110.11 RKO99659.1 - 1.3e-22 79.6 0.0 1.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 RKO99659.1 - 0.0041 16.9 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TACC_C PF05010.14 RKO99660.1 - 5.6e-21 75.2 27.6 1.8e-20 73.6 27.6 1.7 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YabA PF06156.13 RKO99660.1 - 0.014 16.1 2.0 0.014 16.1 2.0 2.4 2 1 0 2 2 2 0 Initiation control protein YabA KASH_CCD PF14662.6 RKO99660.1 - 0.18 11.6 22.2 1.1 9.1 14.8 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TFIIA PF03153.13 RKO99660.1 - 4.8 7.1 13.8 0.16 11.9 7.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hexapep PF00132.24 RKO99661.1 - 4.3e-08 32.6 0.6 0.0027 17.4 0.0 4.2 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RKO99661.1 - 7.1e-05 22.5 0.8 1.1 9.1 0.0 4.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Pex19 PF04614.12 RKO99662.1 - 1e-31 110.6 0.1 7e-31 107.9 0.1 2.4 1 1 1 2 2 2 1 Pex19 protein family Actin PF00022.19 RKO99664.1 - 7.3e-153 509.0 0.0 2.4e-152 507.3 0.0 1.6 1 1 0 1 1 1 1 Actin GerD PF17898.1 RKO99664.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain GAF PF01590.26 RKO99665.1 - 7.2e-21 75.2 0.7 1.4e-14 54.9 0.0 3.7 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.6 RKO99665.1 - 5.6e-12 46.1 0.7 1.1e-06 29.0 0.1 3.1 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 RKO99665.1 - 3.8e-11 43.4 0.4 5.4e-07 30.0 0.0 3.5 3 0 0 3 3 3 2 GAF domain Guanylate_cyc PF00211.20 RKO99665.1 - 0.0012 18.6 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 RKO99665.1 - 0.017 15.2 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99665.1 - 0.034 13.8 1.3 0.042 13.5 0.1 1.8 2 0 0 2 2 2 0 TPR repeat Sacchrp_dh_NADP PF03435.18 RKO99666.1 - 7.2e-15 55.4 0.1 1.2e-14 54.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 RKO99666.1 - 1.9e-05 24.6 0.1 3.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 RKO99666.1 - 0.045 14.2 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 RKO99666.1 - 0.097 12.1 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 RKO99666.1 - 0.2 11.7 0.1 0.61 10.2 0.0 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase OsmC PF02566.19 RKO99668.1 - 5.2e-13 49.3 0.0 6.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein RSN1_7TM PF02714.15 RKO99669.1 - 3.9e-57 193.6 19.5 6.6e-57 192.9 19.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 RKO99669.1 - 4.1e-26 92.3 0.0 1.9e-25 90.1 0.0 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 RKO99669.1 - 4.5e-26 91.5 0.0 4.5e-26 91.5 0.0 3.1 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DREV PF05219.12 RKO99669.1 - 0.15 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Radial_spoke_3 PF06098.11 RKO99671.1 - 3.8e-100 334.8 7.4 4.8e-100 334.5 7.4 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 GntP_permease PF02447.16 RKO99671.1 - 0.05 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 GntP family permease Y_phosphatase PF00102.27 RKO99673.1 - 4.8e-53 180.2 0.2 6.6e-52 176.4 0.2 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RKO99673.1 - 3.2e-05 23.8 0.2 0.00019 21.2 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RKO99673.1 - 0.0012 18.9 0.1 0.0025 17.8 0.1 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Herpes_capsid PF06112.11 RKO99673.1 - 4.6 7.3 10.3 9.1 6.3 10.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AMP-binding PF00501.28 RKO99674.1 - 1.3e-45 155.8 0.7 3.6e-45 154.3 0.7 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO99674.1 - 1.5e-09 38.7 0.4 3.5e-09 37.5 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIA PF03153.13 RKO99675.1 - 0.00095 19.3 29.8 0.0016 18.5 29.8 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 RKO99675.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.19 RKO99676.1 - 5.3e-10 39.6 0.0 7.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO99676.1 - 2.4e-08 34.5 0.0 3.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain ACPS PF01648.20 RKO99677.1 - 1.1e-06 28.8 0.0 2.9e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily SDA1 PF05285.12 RKO99678.1 - 3.3e-40 138.6 51.8 1.2e-29 103.8 20.4 3.2 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 RKO99678.1 - 1.2e-17 63.9 0.0 5e-17 62.0 0.0 2.2 1 0 0 1 1 1 1 NUC130/3NT domain YL1 PF05764.13 RKO99678.1 - 0.011 15.9 1.9 0.011 15.9 1.9 3.1 2 1 0 2 2 2 0 YL1 nuclear protein Adaptin_N PF01602.20 RKO99678.1 - 0.041 12.4 0.0 0.22 10.1 0.0 2.0 1 1 0 1 1 1 0 Adaptin N terminal region CDC45 PF02724.14 RKO99678.1 - 2 6.6 27.8 0.23 9.7 2.2 2.4 2 0 0 2 2 2 0 CDC45-like protein Nop53 PF07767.11 RKO99678.1 - 3.9 6.8 34.4 0.79 9.0 3.9 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Cortex-I_coil PF09304.10 RKO99679.1 - 0.0014 18.8 0.3 0.0027 17.9 0.3 1.4 1 0 0 1 1 1 1 Cortexillin I, coiled coil Peptidase_S46 PF10459.9 RKO99679.1 - 0.024 13.3 3.1 0.034 12.8 3.1 1.1 1 0 0 1 1 1 0 Peptidase S46 MAD PF05557.13 RKO99679.1 - 0.051 11.9 0.3 0.067 11.6 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein SlyX PF04102.12 RKO99679.1 - 0.075 13.7 0.3 0.24 12.1 0.3 1.8 1 0 0 1 1 1 0 SlyX BRE1 PF08647.11 RKO99679.1 - 0.18 11.9 2.5 0.29 11.2 2.5 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 RKO99679.1 - 0.63 9.3 5.7 0.94 8.8 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MutS_V PF00488.21 RKO99680.1 - 1.2e-62 211.3 0.0 1.5e-61 207.7 0.0 2.9 4 0 0 4 4 4 1 MutS domain V MutS_III PF05192.18 RKO99680.1 - 3.4e-31 109.0 1.6 4.2e-31 108.7 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 RKO99680.1 - 6.2e-26 90.9 0.0 1.4e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 RKO99680.1 - 4.7e-09 36.6 0.3 1.4e-08 35.1 0.3 1.9 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RKO99680.1 - 9.2e-08 32.3 0.0 2.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV Pox_A_type_inc PF04508.12 RKO99682.1 - 2.9 7.9 7.8 3.8 7.5 0.7 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat LPP PF04728.13 RKO99682.1 - 7.5 7.0 21.1 0.62 10.5 0.5 6.3 6 0 0 6 6 6 0 Lipoprotein leucine-zipper CAF1 PF04857.20 RKO99684.1 - 1.9e-76 257.3 0.0 3.5e-76 256.4 0.0 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_pol_Rpb6 PF01192.22 RKO99685.1 - 3.3e-16 58.9 0.1 4.6e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RhoGAP PF00620.27 RKO99686.1 - 3.5e-11 43.2 0.0 2.5e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain NDUF_B12 PF08122.12 RKO99686.1 - 4.2e-11 42.7 0.6 9.9e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Exo_endo_phos PF03372.23 RKO99686.1 - 3.4e-09 36.5 0.1 6.6e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LTV PF04180.14 RKO99687.1 - 1.4e-34 120.5 21.6 7e-33 114.9 14.7 2.6 2 1 0 2 2 2 2 Low temperature viability protein Med10 PF09748.9 RKO99687.1 - 0.19 11.7 2.0 0.88 9.5 0.3 2.5 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex U1snRNP70_N PF12220.8 RKO99687.1 - 0.73 10.5 13.6 0.44 11.2 1.0 3.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-CCCH_4 PF18044.1 RKO99688.1 - 5.6e-05 22.8 3.2 9.4e-05 22.1 3.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger PAM2 PF07145.15 RKO99688.1 - 9.4e-05 21.8 2.6 0.2 11.4 0.4 2.7 2 0 0 2 2 2 2 Ataxin-2 C-terminal region zf-CCCH_2 PF14608.6 RKO99688.1 - 0.00023 21.5 5.2 0.00042 20.7 5.2 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 RKO99688.1 - 0.00074 19.4 2.8 0.0013 18.6 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TRAP_alpha PF03896.16 RKO99688.1 - 0.012 14.8 1.0 0.027 13.7 1.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf_CCCH_4 PF18345.1 RKO99688.1 - 0.025 14.6 2.5 0.047 13.8 2.5 1.5 1 0 0 1 1 1 0 Zinc finger domain Proteasome PF00227.26 RKO99689.1 - 1.8e-46 158.0 0.0 2.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKO99689.1 - 1.9e-13 49.8 0.1 6.2e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosomal_L12 PF00542.19 RKO99690.1 - 9.9e-21 73.9 6.8 9.9e-21 73.9 6.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 RKO99690.1 - 1.7e-08 34.1 23.1 1.7e-08 34.1 23.1 3.9 3 2 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 RKO99690.1 - 0.00032 21.2 12.5 0.00032 21.2 12.5 2.3 1 1 1 2 2 2 1 60s Acidic ribosomal protein Bac_DNA_binding PF00216.21 RKO99690.1 - 0.016 15.4 0.8 0.016 15.4 0.8 1.9 2 0 0 2 2 2 0 Bacterial DNA-binding protein Cas_Csy2 PF09614.10 RKO99690.1 - 0.022 14.1 0.1 0.033 13.6 0.1 1.4 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) MelC1 PF06236.11 RKO99690.1 - 0.1 12.7 4.0 0.15 12.2 4.0 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 UQ_con PF00179.26 RKO99692.1 - 9.9e-16 57.7 0.0 1e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKO99692.1 - 0.00013 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 RKO99692.1 - 0.022 15.0 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain UPF0203 PF05254.12 RKO99693.1 - 2e-24 85.6 1.6 2.3e-24 85.4 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 RKO99693.1 - 0.031 14.5 1.1 0.28 11.4 0.9 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 RKO99693.1 - 0.087 13.2 0.8 0.34 11.3 0.8 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) PACT_coil_coil PF10495.9 RKO99694.1 - 1.4e-11 44.8 1.2 1.4e-11 44.8 1.2 6.4 6 2 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein APG6_N PF17675.1 RKO99694.1 - 0.00095 19.7 14.0 0.00095 19.7 14.0 22.9 8 4 12 20 20 20 6 Apg6 coiled-coil region AAA_31 PF13614.6 RKO99694.1 - 0.36 10.7 4.0 0.2 11.5 0.4 2.5 2 0 0 2 2 2 0 AAA domain Baculo_LEF-10 PF07206.11 RKO99694.1 - 1.3 9.2 4.2 12 6.2 0.1 4.4 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) ATP-synt_E PF05680.12 RKO99695.1 - 8.6e-13 48.5 0.3 1e-12 48.2 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain Proteasome PF00227.26 RKO99696.1 - 1e-32 113.2 0.0 7.1e-32 110.4 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 RKO99697.1 - 8.2e-51 172.2 0.2 9.9e-51 171.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit BBS2_Mid PF14783.6 RKO99697.1 - 0.079 13.0 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nefa_Nip30_N PF10187.9 RKO99698.1 - 1.4e-14 54.3 1.6 2.8e-14 53.3 1.6 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 zf-NADH-PPase PF09297.11 RKO99699.1 - 0.35 10.6 7.3 0.83 9.4 7.3 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Med3 PF11593.8 RKO99699.1 - 4.6 6.3 10.2 8.7 5.4 10.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_transf_20 PF00982.21 RKO99700.1 - 3.9e-191 635.9 0.0 4.7e-191 635.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RKO99700.1 - 1.7e-48 164.8 0.0 3.7e-31 108.1 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Glyco_transf_5 PF08323.11 RKO99700.1 - 0.048 13.3 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain RPN7 PF10602.9 RKO99701.1 - 2.9e-53 180.1 0.1 4.2e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 RKO99701.1 - 1.3e-12 48.1 0.0 2.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 RKO99701.1 - 0.053 14.4 10.9 0.45 11.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3785 PF12653.7 RKO99701.1 - 0.09 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) NRDE-2 PF08424.10 RKO99701.1 - 0.15 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference WD40 PF00400.32 RKO99702.1 - 1.2e-51 171.5 21.5 1.3e-08 35.3 0.0 12.4 11 1 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99702.1 - 2.1e-19 69.6 4.2 0.00042 20.6 0.0 7.5 4 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 RKO99702.1 - 1.2e-13 51.2 0.2 2.6e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 RKO99702.1 - 2.3e-08 33.4 7.8 0.33 9.8 0.0 6.5 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 RKO99702.1 - 1.6e-05 24.4 1.1 0.21 10.9 0.0 3.8 3 1 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 RKO99702.1 - 0.00076 18.3 13.5 1.8 7.1 0.2 6.6 7 3 2 9 9 9 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RKO99702.1 - 0.002 17.5 0.0 7.6 5.8 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Frtz PF11768.8 RKO99702.1 - 0.0031 15.9 0.0 3 6.0 0.0 3.2 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 RKO99702.1 - 0.048 12.2 0.2 0.14 10.7 0.2 1.7 1 0 0 1 1 1 0 Cytochrome D1 heme domain Brix PF04427.18 RKO99703.1 - 1.2e-37 130.0 0.1 1.4e-37 129.7 0.1 1.1 1 0 0 1 1 1 1 Brix domain tRNA-synt_2c PF01411.19 RKO99704.1 - 7.9e-206 684.8 0.0 9.7e-206 684.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 RKO99704.1 - 2.2e-15 56.5 0.1 5.4e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 RKO99704.1 - 6.5e-07 29.9 4.3 1.4e-06 28.8 4.3 1.5 1 0 0 1 1 1 1 DHHA1 domain IF-2B PF01008.17 RKO99705.1 - 2.1e-58 197.8 0.0 2.4e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family CENP-S PF15630.6 RKO99705.1 - 0.011 16.1 0.9 0.35 11.3 0.3 2.4 2 0 0 2 2 2 0 CENP-S protein ZapD PF07072.11 RKO99705.1 - 0.11 12.3 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Cell division protein AAA_6 PF12774.7 RKO99706.1 - 7e-155 514.9 0.0 3.5e-154 512.7 0.0 2.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKO99706.1 - 6e-134 447.1 2.2 6e-134 447.1 2.2 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKO99706.1 - 5.6e-109 364.1 0.0 2.7e-107 358.5 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKO99706.1 - 1.1e-98 329.7 0.0 1.1e-97 326.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKO99706.1 - 1.1e-90 302.6 0.4 1.1e-90 302.6 0.4 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKO99706.1 - 2.6e-76 255.2 0.2 6.4e-74 247.4 0.0 3.5 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKO99706.1 - 7e-60 201.6 0.0 5.3e-58 195.5 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 RKO99706.1 - 7.8e-56 189.6 9.0 7.8e-56 189.6 9.0 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RKO99706.1 - 3.3e-47 159.5 0.0 4.3e-44 149.4 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RKO99706.1 - 1.4e-21 76.9 0.1 4.4e-21 75.3 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RKO99706.1 - 2.2e-19 69.8 0.0 0.00036 20.6 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RKO99706.1 - 3.4e-17 62.5 0.0 1.4e-16 60.5 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 RKO99706.1 - 3.2e-07 30.8 0.1 0.025 15.0 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKO99706.1 - 3.1e-05 24.4 0.0 13 6.2 0.0 4.8 4 0 0 4 4 3 0 AAA ATPase domain T2SSE PF00437.20 RKO99706.1 - 0.00031 19.9 0.0 0.49 9.4 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 RKO99706.1 - 0.0013 19.1 1.2 2.8 8.2 0.0 5.2 6 0 0 6 6 5 1 AAA domain AAA_30 PF13604.6 RKO99706.1 - 0.0069 16.1 0.0 2.3 7.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RKO99706.1 - 0.0091 15.4 0.0 0.37 10.1 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 RKO99706.1 - 0.024 15.0 0.0 27 5.2 0.0 3.6 3 0 0 3 3 3 0 RNA helicase PI3K_P85_iSH2 PF16454.5 RKO99706.1 - 0.096 12.3 2.9 0.15 11.7 0.5 2.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sigma54_activat PF00158.26 RKO99706.1 - 0.13 12.0 0.0 1 9.0 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 RKO99706.1 - 0.17 12.5 0.0 2.2 8.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain EloA-BP1 PF15870.5 RKO99706.1 - 0.92 9.7 3.0 0.51 10.6 0.4 1.8 2 0 0 2 2 2 0 ElonginA binding-protein 1 TolA_bind_tri PF16331.5 RKO99706.1 - 6.3 7.0 7.5 1.6 8.8 0.6 3.2 2 0 0 2 2 2 0 TolA binding protein trimerisation MRP-S28 PF10213.9 RKO99707.1 - 0.069 13.6 0.0 0.41 11.1 0.0 2.1 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit protein FUSC PF04632.12 RKO99708.1 - 0.35 9.4 7.7 0.52 8.8 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM176 PF14851.6 RKO99708.1 - 2.5 7.7 8.5 0.53 9.9 3.9 2.1 2 0 0 2 2 2 0 FAM176 family SDA1 PF05285.12 RKO99708.1 - 4 6.8 20.6 0.59 9.5 15.3 1.9 2 0 0 2 2 2 0 SDA1 DUF2722 PF10846.8 RKO99708.1 - 8.2 5.2 7.9 13 4.6 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Thioredoxin PF00085.20 RKO99709.1 - 1.5e-24 85.9 0.0 1.9e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 RKO99709.1 - 0.00024 21.5 0.1 0.003 18.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 RKO99709.1 - 0.00085 18.8 0.1 0.00096 18.6 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RKO99709.1 - 0.0048 17.2 0.0 0.008 16.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 RKO99709.1 - 0.011 15.9 0.3 0.018 15.2 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 RKO99709.1 - 0.025 14.5 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 RKO99709.1 - 0.044 13.6 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Gelsolin PF00626.22 RKO99710.1 - 7.3e-29 99.5 0.0 7.7e-09 35.3 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat V-SNARE_C PF12352.8 RKO99711.1 - 4.7e-11 42.8 0.8 4.7e-11 42.8 0.8 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Hist_deacetyl PF00850.19 RKO99714.1 - 2.1e-68 231.1 0.2 3.3e-68 230.4 0.2 1.3 1 1 0 1 1 1 1 Histone deacetylase domain Ras PF00071.22 RKO99715.1 - 5.7e-46 156.1 0.0 6.5e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO99715.1 - 1.8e-15 57.2 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO99715.1 - 4.2e-05 23.1 0.0 5.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO99715.1 - 0.00032 20.3 0.1 0.0014 18.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKO99715.1 - 0.00038 20.4 0.0 0.043 13.7 0.0 2.1 1 1 1 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RKO99715.1 - 0.0056 16.8 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 RKO99715.1 - 0.054 13.5 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 RKO99715.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 RKO99715.1 - 0.13 11.8 0.0 0.38 10.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Sugar_tr PF00083.24 RKO99716.1 - 3.7e-121 405.1 25.3 4.2e-121 405.0 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RKO99716.1 - 1.6e-28 99.7 45.1 3e-24 85.6 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RKO99716.1 - 2.4e-06 26.7 17.6 0.0054 15.6 4.1 2.6 1 1 2 3 3 3 2 MFS_1 like family TRI12 PF06609.13 RKO99716.1 - 0.00024 19.7 4.2 0.00024 19.7 4.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM100 PF16311.5 RKO99716.1 - 0.39 10.3 4.3 0.17 11.5 1.2 2.0 1 1 1 2 2 2 0 Transmembrane protein 100 UNC-93 PF05978.16 RKO99716.1 - 1.2 8.8 16.4 0.017 14.9 5.7 2.6 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 OATP PF03137.20 RKO99716.1 - 2.6 6.2 8.1 0.78 8.0 4.5 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Vfa1 PF08432.10 RKO99717.1 - 0.48 10.7 8.3 0.87 9.9 8.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Exonuc_VII_L PF02601.15 RKO99717.1 - 0.69 9.4 17.2 1.3 8.5 17.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit COesterase PF00135.28 RKO99717.1 - 0.78 8.5 4.6 1.1 8.0 4.6 1.2 1 0 0 1 1 1 0 Carboxylesterase family Spt20 PF12090.8 RKO99717.1 - 3 7.4 20.2 6 6.4 20.2 1.5 1 0 0 1 1 1 0 Spt20 family DHR-2 PF06920.13 RKO99718.1 - 1e-62 212.5 0.0 1.2e-28 100.1 0.0 3.7 4 0 0 4 4 4 3 Dock homology region 2 DOCK_N PF16172.5 RKO99718.1 - 8.1e-25 87.5 0.0 1.5e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 RKO99718.1 - 2.6e-18 66.5 0.0 5.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins IPTL-CTERM PF18203.1 RKO99719.1 - 0.39 10.7 2.3 0.9 9.5 2.3 1.6 1 0 0 1 1 1 0 IPTL-CTERM motif Methyltransf_32 PF13679.6 RKO99720.1 - 9.4e-21 74.4 0.0 1.4e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ank_5 PF13857.6 RKO99721.1 - 1.4e-08 34.8 0.5 2.1e-08 34.2 0.4 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKO99721.1 - 2.7e-06 27.9 0.1 3.2e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKO99721.1 - 2.8e-05 24.2 0.1 0.00032 20.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RKO99721.1 - 0.00015 22.1 0.8 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat ASF1_hist_chap PF04729.13 RKO99723.1 - 1.3e-55 187.6 0.0 1.5e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone TMEM208_SND2 PF05620.11 RKO99724.1 - 6.9e-17 61.7 0.0 7.5e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 CSTF2_hinge PF14327.6 RKO99725.1 - 4e-15 56.0 3.0 4e-15 56.0 3.0 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 RKO99725.1 - 1e-14 54.1 0.0 1.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 RKO99725.1 - 6e-11 41.8 10.1 6e-11 41.8 10.1 1.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.6 RKO99725.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKO99725.1 - 0.013 15.3 0.0 0.066 13.1 0.0 2.0 1 1 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 RKO99726.1 - 9.6e-08 32.6 2.6 0.053 14.4 0.1 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99726.1 - 0.01 16.1 0.0 0.17 12.2 0.0 2.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF724 PF05266.14 RKO99727.1 - 0.0068 16.2 2.3 0.0068 16.2 2.3 12.4 5 2 8 14 14 14 4 Protein of unknown function (DUF724) DNA_RNApol_7kD PF03604.13 RKO99728.1 - 5.6e-17 61.1 7.5 8e-17 60.6 7.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 RKO99728.1 - 0.007 16.2 0.6 0.0089 15.9 0.6 1.1 1 0 0 1 1 1 1 MCM OB domain DZR PF12773.7 RKO99728.1 - 0.02 14.9 1.6 0.023 14.7 0.8 1.5 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 RKO99728.1 - 0.067 13.1 2.7 0.53 10.2 0.2 2.5 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_10 PF10058.9 RKO99728.1 - 0.067 12.9 2.2 0.46 10.2 0.2 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 RKO99728.1 - 0.08 13.0 0.8 0.098 12.7 0.8 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF951 PF06107.11 RKO99728.1 - 0.11 12.4 1.5 0.16 11.9 1.3 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DUF1451 PF07295.11 RKO99728.1 - 0.14 12.2 0.9 0.17 11.9 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_ribbon_recom PF13408.6 RKO99728.1 - 0.16 12.5 5.8 0.22 12.1 0.6 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 RKO99728.1 - 0.37 11.0 4.5 1.4 9.1 4.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 RKO99728.1 - 0.61 9.7 2.3 13 5.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 RKO99728.1 - 0.84 9.4 6.0 7.2 6.4 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-trcl PF13451.6 RKO99728.1 - 1.4 8.9 5.1 7.6 6.5 1.5 2.6 2 1 0 2 2 2 0 Probable zinc-ribbon domain Ferrochelatase PF00762.19 RKO99729.1 - 6.1e-112 373.8 0.0 7.2e-112 373.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF4921 PF16268.5 RKO99729.1 - 0.055 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) Thioredoxin PF00085.20 RKO99730.1 - 1.5e-28 98.8 0.1 1.7e-27 95.4 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 RKO99730.1 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 RKO99730.1 - 0.00026 21.3 0.0 0.00072 19.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO99730.1 - 0.00089 19.7 0.1 0.14 12.6 0.1 2.6 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RKO99730.1 - 0.0011 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 RKO99730.1 - 0.0049 16.7 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 RKO99730.1 - 0.0076 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin HMG_CoA_synt_N PF01154.17 RKO99732.1 - 1.2e-80 269.5 0.0 1.6e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 RKO99732.1 - 4.1e-71 239.9 0.0 5.6e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal adh_short PF00106.25 RKO99733.1 - 6.4e-32 110.6 3.1 7.7e-32 110.3 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO99733.1 - 2.4e-20 73.1 4.2 2.8e-20 72.9 4.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO99733.1 - 2.9e-12 46.9 2.0 4.7e-12 46.2 2.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO99733.1 - 1.5e-05 24.6 0.8 2.6e-05 23.8 0.8 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RKO99733.1 - 0.00044 19.5 3.8 0.36 9.9 3.8 2.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 RKO99733.1 - 0.039 13.9 2.4 0.062 13.2 2.4 1.4 1 1 0 1 1 1 0 NAD(P)H-binding TPR_2 PF07719.17 RKO99737.1 - 5.8e-16 57.2 7.7 8.1e-07 28.7 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 RKO99737.1 - 2.5e-12 46.1 4.1 2.3e-06 27.1 0.1 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99737.1 - 1.4e-11 43.6 0.3 0.034 14.3 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99737.1 - 3.1e-11 43.7 19.1 1.6e-06 28.6 13.4 3.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99737.1 - 1.5e-09 37.4 9.4 8.5e-05 22.2 0.1 4.9 3 1 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 RKO99737.1 - 2.6e-08 33.7 3.9 0.1 13.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99737.1 - 3.1e-08 33.8 14.9 8.7e-06 25.9 0.4 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99737.1 - 4.1e-08 32.7 2.0 0.11 12.5 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKO99737.1 - 7.3e-06 26.4 12.4 0.059 13.9 8.7 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 RKO99737.1 - 0.00013 21.7 12.4 0.38 10.7 0.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 RKO99737.1 - 0.00033 21.2 18.8 0.003 18.2 0.4 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 RKO99737.1 - 0.00052 20.4 19.0 0.0021 18.5 0.6 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99737.1 - 0.0065 17.0 1.4 5.7 7.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 RKO99737.1 - 0.016 15.3 2.9 0.079 13.0 1.4 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 RKO99737.1 - 0.1 13.0 9.1 0.2 12.1 4.4 2.7 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 RKO99737.1 - 0.39 10.9 11.2 2.3 8.4 0.7 3.9 1 1 1 3 3 3 0 Tetratricopeptide repeat BatD PF13584.6 RKO99738.1 - 0.0021 17.0 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Oxygen tolerance PRCC PF10253.9 RKO99738.1 - 0.013 16.3 0.7 0.013 16.3 0.7 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting TMEM154 PF15102.6 RKO99738.1 - 0.041 13.8 0.3 0.079 12.9 0.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family Secretin_N_2 PF07655.13 RKO99738.1 - 0.96 10.0 9.6 1.7 9.2 9.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain WD40 PF00400.32 RKO99739.1 - 2.8e-07 31.1 21.7 0.00027 21.7 0.1 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 RKO99739.1 - 8.1e-06 25.4 15.6 8.1e-06 25.4 15.6 2.5 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 RKO99739.1 - 1.2e-05 25.6 0.2 0.13 12.6 0.1 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BiPBP_C PF06832.12 RKO99739.1 - 0.05 13.6 0.2 0.15 12.1 0.2 1.9 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family DZR PF12773.7 RKO99739.1 - 0.17 11.9 13.4 0.42 10.7 13.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-rbx1 PF12678.7 RKO99739.1 - 0.46 10.8 14.9 0.13 12.6 10.0 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO99739.1 - 1.8 8.6 16.6 2.7 8.0 6.5 2.9 2 1 0 2 2 2 0 zinc-RING finger domain Noc2 PF03715.13 RKO99741.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Noc2p family ATP-synt_ab PF00006.25 RKO99743.1 - 1.4e-68 230.7 0.0 2.3e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RKO99743.1 - 1.5e-10 41.5 0.8 3.1e-10 40.4 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 RKO99743.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Glyco_transf_22 PF03901.17 RKO99744.1 - 1.1e-09 38.0 0.8 1.3e-09 37.8 0.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase_Tyr PF07714.17 RKO99745.1 - 1.1e-33 116.7 0.0 1.2e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 RKO99745.1 - 3.1e-27 95.6 0.0 3.7e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Mito_carr PF00153.27 RKO99746.1 - 1.1e-59 198.4 1.6 1.8e-20 72.7 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RKO99746.1 - 0.036 13.2 0.2 0.22 10.6 0.0 2.3 3 0 0 3 3 3 0 Gammaproteobacterial serine protease RCDG1 PF15725.5 RKO99746.1 - 0.15 12.5 5.4 0.3 11.5 5.4 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein 17kDa_Anti_2 PF16998.5 RKO99746.1 - 0.24 11.3 2.1 0.57 10.1 1.1 2.0 2 0 0 2 2 2 0 17 kDa outer membrane surface antigen DUF2043 PF09740.9 RKO99747.1 - 1.1e-21 77.5 0.0 1.9e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) DNA_pol_phi PF04931.13 RKO99747.1 - 0.47 8.5 3.1 0.64 8.0 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi XPG_N PF00752.17 RKO99748.1 - 5.5e-35 119.9 0.0 9.8e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RKO99748.1 - 5.7e-30 103.5 0.0 1.1e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 RKO99748.1 - 0.00027 21.5 0.0 0.00076 20.0 0.0 1.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 RKO99748.1 - 0.0018 18.9 0.0 0.0039 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Exo_endo_phos PF03372.23 RKO99749.1 - 1.4e-25 90.2 0.4 2.9e-25 89.1 0.4 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 RKO99749.1 - 7.8e-13 48.0 23.9 9.8e-07 28.4 4.2 2.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 RKO99749.1 - 6.2e-10 39.2 3.2 3.7e-05 24.0 0.6 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKO99749.1 - 0.013 15.9 4.2 15 6.6 0.2 4.8 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 RKO99749.1 - 0.098 12.8 5.2 6.8 7.0 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeat DUF3719 PF12516.8 RKO99750.1 - 0.17 11.6 1.8 0.37 10.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3719) RNA_polI_A34 PF08208.11 RKO99750.1 - 0.79 9.8 5.1 1.2 9.2 5.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glycos_transf_1 PF00534.20 RKO99751.1 - 7e-23 81.0 0.0 4.7e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RKO99751.1 - 8.2e-17 61.7 3.3 8.2e-17 61.7 3.3 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 RKO99751.1 - 7.2e-10 39.4 0.1 2.8e-08 34.3 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RKO99751.1 - 0.0084 16.5 0.5 0.032 14.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 SAM_2 PF07647.17 RKO99752.1 - 2.1e-09 37.4 0.0 2.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RKO99752.1 - 2.6e-05 24.6 0.0 4.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 RKO99752.1 - 0.021 14.9 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 IGR protein motif CHORD PF04968.12 RKO99753.1 - 7.4e-51 170.7 12.7 8.5e-28 96.9 3.0 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 RKO99753.1 - 6.6e-15 55.9 0.0 9.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 CS domain Ribul_P_3_epim PF00834.19 RKO99754.1 - 2.6e-73 245.6 0.0 3.1e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 RKO99754.1 - 0.0063 16.1 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 RKO99754.1 - 0.062 12.6 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 RKO99754.1 - 0.067 12.6 0.1 0.54 9.7 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein NAT PF04768.13 RKO99755.1 - 5e-34 117.4 0.0 8.4e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_1 PF00583.25 RKO99755.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ING PF12998.7 RKO99756.1 - 2e-16 60.4 3.2 3.4e-16 59.7 3.2 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 RKO99756.1 - 4e-06 26.6 8.5 6.6e-06 25.9 8.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RKO99756.1 - 0.0057 16.9 1.1 0.011 16.0 1.1 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain TACC_C PF05010.14 RKO99756.1 - 0.014 15.2 1.1 0.022 14.6 1.1 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-HC5HC2H_2 PF13832.6 RKO99756.1 - 0.019 15.1 0.5 0.034 14.3 0.5 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain PAS_8 PF13188.7 RKO99756.1 - 0.12 12.4 0.1 0.33 11.0 0.1 1.9 1 1 0 1 1 1 0 PAS domain WLM PF08325.10 RKO99756.1 - 0.43 10.6 4.6 0.91 9.6 4.5 1.7 1 1 0 1 1 1 0 WLM domain DUF4407 PF14362.6 RKO99756.1 - 0.47 9.7 4.6 1.2 8.4 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SAS-6_N PF16531.5 RKO99757.1 - 4.2e-25 88.2 0.0 7.2e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal AAA_13 PF13166.6 RKO99757.1 - 0.00012 21.0 20.9 0.00012 21.0 20.9 2.1 1 1 1 2 2 2 2 AAA domain Lebercilin PF15619.6 RKO99757.1 - 0.0054 16.4 20.8 0.0054 16.4 20.8 3.0 1 1 1 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 RKO99757.1 - 0.0079 16.2 1.1 0.0079 16.2 1.1 6.1 2 2 5 7 7 7 2 TATA element modulatory factor 1 DNA binding Sas6_CC PF18594.1 RKO99757.1 - 0.075 12.8 0.0 0.32 10.8 0.0 2.2 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain TSC22 PF01166.18 RKO99757.1 - 0.086 13.2 9.7 0.1 12.9 0.1 4.0 4 0 0 4 4 4 0 TSC-22/dip/bun family Spc7 PF08317.11 RKO99757.1 - 0.12 11.3 53.9 0.019 13.8 15.3 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 RKO99757.1 - 0.13 12.3 70.1 0.038 14.1 18.4 3.8 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 RKO99757.1 - 0.69 10.1 25.6 0.37 11.0 2.6 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.10 RKO99757.1 - 1.5 9.2 6.0 27 5.1 0.2 4.2 4 0 0 4 4 4 0 Osmosensory transporter coiled coil DUF722 PF05263.11 RKO99757.1 - 2.3 8.4 5.8 2.6 8.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF722) YabA PF06156.13 RKO99757.1 - 7.1 7.3 27.3 3.4 8.4 2.4 4.4 2 1 1 4 4 4 0 Initiation control protein YabA START PF01852.19 RKO99758.1 - 7.6e-17 61.4 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 START domain LIM PF00412.22 RKO99759.1 - 2.4e-22 78.9 11.1 4.9e-11 42.7 2.8 2.4 2 0 0 2 2 2 2 LIM domain zinc_ribbon_12 PF11331.8 RKO99759.1 - 0.11 12.4 6.4 0.18 11.6 0.4 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain Crust_neurohorm PF01147.17 RKO99759.1 - 0.14 12.0 1.5 0.3 11.0 1.5 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family DZR PF12773.7 RKO99759.1 - 0.25 11.4 7.4 0.64 10.1 1.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon SelP_N PF04592.14 RKO99759.1 - 6.3 6.1 17.2 1.7 8.0 14.3 1.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Aa_trans PF01490.18 RKO99760.1 - 2.4e-09 36.4 4.2 2.4e-09 36.4 4.2 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RKO99760.1 - 2.8e-06 26.6 1.5 2.8e-06 26.6 1.5 2.8 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family Rhodanese PF00581.20 RKO99761.1 - 1.5e-26 93.0 0.0 2.1e-13 50.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Ctf8 PF09696.10 RKO99762.1 - 1.4e-11 44.9 0.2 2e-10 41.2 0.1 2.0 1 1 1 2 2 2 1 Ctf8 CC2D2AN-C2 PF15625.6 RKO99763.1 - 1.5e-05 24.8 0.0 0.00021 21.1 0.0 2.4 2 1 0 2 2 2 1 CC2D2A N-terminal C2 domain Hydrophobin PF01185.18 RKO99764.1 - 1.2e-05 25.8 9.9 3.4e-05 24.4 10.0 1.6 1 1 1 2 2 2 2 Fungal hydrophobin AAA_12 PF13087.6 RKO99765.1 - 2.6e-40 138.2 0.0 4.2e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKO99765.1 - 3e-27 96.1 0.0 4.6e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO99765.1 - 3.2e-10 40.5 0.0 6.5e-09 36.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RKO99765.1 - 3.2e-08 33.5 0.1 0.00043 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 RKO99765.1 - 1.9e-05 24.4 0.0 5.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 RKO99765.1 - 0.0014 18.0 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 RKO99765.1 - 0.014 15.1 0.0 0.18 11.6 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 RKO99765.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 RKO99765.1 - 0.018 15.4 0.1 0.097 13.1 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 RKO99765.1 - 0.052 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RKO99765.1 - 0.072 13.4 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RKO99765.1 - 0.088 13.2 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3818 PF12825.7 RKO99766.1 - 2.2e-17 63.1 0.2 8.6e-10 38.1 0.1 2.1 1 1 0 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) pPIWI_RE_REase PF18154.1 RKO99766.1 - 0.014 15.3 0.1 0.038 14.0 0.1 1.8 1 0 0 1 1 1 0 REase associating with pPIWI_RE Retinal PF15449.6 RKO99766.1 - 0.25 9.1 1.2 0.36 8.6 1.2 1.1 1 0 0 1 1 1 0 Retinal protein Stm1_N PF09598.10 RKO99766.1 - 0.31 11.9 2.1 0.71 10.8 2.1 1.6 1 0 0 1 1 1 0 Stm1 Homeodomain PF00046.29 RKO99767.1 - 1.7e-07 30.9 0.0 4.1e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Homeodomain zf_CCCH_4 PF18345.1 RKO99767.1 - 2e-05 24.4 8.2 3.2e-05 23.8 8.2 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RKO99767.1 - 3.1e-05 23.7 3.4 5.1e-05 23.1 3.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RKO99767.1 - 0.00032 20.4 6.0 0.00052 19.8 6.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 RKO99767.1 - 0.0023 17.9 0.2 0.0055 16.7 0.1 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Torus PF16131.5 RKO99767.1 - 0.033 14.9 0.5 0.064 14.0 0.5 1.4 1 0 0 1 1 1 0 Torus domain FYDLN_acid PF09538.10 RKO99767.1 - 8.9 7.0 9.0 5.5 7.7 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4054 PF13262.6 RKO99768.1 - 0.06 13.4 0.8 0.15 12.1 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) DNase-RNase PF02577.14 RKO99768.1 - 0.12 12.0 0.1 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Bifunctional nuclease Helicase_C_2 PF13307.6 RKO99769.1 - 1.6e-50 171.6 0.0 7.8e-50 169.4 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 RKO99769.1 - 1.2e-43 148.8 0.5 2.6e-43 147.7 0.5 1.5 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 RKO99769.1 - 6.6e-05 23.0 0.0 0.17 11.9 0.1 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO99769.1 - 0.00066 19.5 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HBB PF06777.11 RKO99769.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain Baculo_F PF12259.8 RKO99769.1 - 0.028 13.0 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein PhoH PF02562.16 RKO99769.1 - 0.044 13.2 0.0 7.5 5.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 RKO99769.1 - 0.057 12.1 0.4 0.33 9.6 0.4 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.6 RKO99769.1 - 0.077 13.3 0.3 0.26 11.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain FtsX PF02687.21 RKO99770.1 - 1.1e-17 64.3 18.4 1e-11 45.1 6.4 6.7 6 1 1 7 7 7 2 FtsX-like permease family HAGH_C PF16123.5 RKO99771.1 - 2.3e-18 66.5 0.0 4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 RKO99771.1 - 1.3e-10 41.7 5.7 2e-09 37.7 5.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RKO99771.1 - 0.007 15.9 2.8 0.049 13.1 2.5 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RKO99771.1 - 0.048 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Suc_Fer-like PF06999.12 RKO99771.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like SPX PF03105.19 RKO99772.1 - 2.7e-31 109.9 1.2 1.4e-14 54.9 0.0 3.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 RKO99772.1 - 9.8e-22 77.6 35.3 1.5e-21 77.0 35.3 1.3 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 RKO99772.1 - 2.1e-16 60.0 90.6 2.7e-15 56.4 41.3 2.0 1 1 2 3 3 3 3 Citrate transporter CH PF00307.31 RKO99773.1 - 1.7e-28 98.9 0.0 9.3e-18 64.4 0.0 3.8 3 2 0 3 3 3 2 Calponin homology (CH) domain GAS2 PF02187.17 RKO99773.1 - 6.7e-12 45.3 0.1 2.1e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Vps5 PF09325.10 RKO99773.1 - 0.32 10.5 2.2 7.7 6.0 0.0 4.1 4 0 0 4 4 4 0 Vps5 C terminal like BLOC1_2 PF10046.9 RKO99773.1 - 0.97 9.8 2.6 37 4.7 0.1 4.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TH1 PF04858.13 RKO99776.1 - 2.7e-09 36.2 0.0 3.6e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 TH1 protein zf-CCHC_2 PF13696.6 RKO99777.1 - 1.9e-10 40.3 23.3 4e-06 26.5 1.6 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 RKO99777.1 - 0.0038 17.1 13.2 0.35 10.9 0.8 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 RKO99777.1 - 0.14 11.9 15.4 1.2 9.0 0.6 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.23 RKO99777.1 - 3.7 7.8 17.4 1.2 9.3 0.9 3.3 3 0 0 3 3 3 0 Zinc knuckle I_LWEQ PF01608.17 RKO99778.1 - 1.8e-47 161.4 160.4 1.9e-40 138.6 8.3 15.8 7 5 7 15 15 15 9 I/LWEQ domain FERM_M PF00373.18 RKO99778.1 - 5.5e-26 91.3 0.1 5.7e-25 88.0 0.1 2.9 2 0 0 2 2 2 1 FERM central domain Talin_middle PF09141.10 RKO99778.1 - 6.6e-26 91.3 7.3 6.6e-26 91.3 7.3 15.3 8 5 8 16 16 16 5 Talin, middle domain FERM_f0 PF16511.5 RKO99778.1 - 2.4e-18 66.2 0.0 3e-17 62.7 0.0 2.9 3 0 0 3 3 3 1 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 RKO99778.1 - 1.5e-08 34.5 0.0 4.5e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 FERM N-terminal domain IRS PF02174.17 RKO99778.1 - 0.0002 21.2 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 PTB domain (IRS-1 type) Kindlin_2_N PF18124.1 RKO99778.1 - 0.015 15.4 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 Kindlin-2 N-terminal domain SMC_N PF02463.19 RKO99779.1 - 1.8e-70 236.8 0.0 2.7e-70 236.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RKO99779.1 - 4.2e-25 88.3 0.0 2e-24 86.1 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 RKO99779.1 - 5.3e-18 65.9 6.2 1.5e-11 44.7 0.3 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 RKO99779.1 - 1.6e-16 61.0 1.3 1.1e-08 35.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 RKO99779.1 - 1.3e-14 55.2 21.4 1.3e-14 55.2 21.4 6.1 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 RKO99779.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 RKO99779.1 - 1.8 8.6 0.0 1.8 8.6 0.0 5.1 3 1 0 4 4 4 0 Helicase HerA, central domain ABC_tran PF00005.27 RKO99779.1 - 1.9 9.0 0.0 1.9 9.0 0.0 5.5 3 2 1 4 4 4 0 ABC transporter DUF2316 PF10078.9 RKO99779.1 - 2.3 8.5 6.7 1 9.7 0.3 3.8 3 2 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) Rad9 PF04139.13 RKO99780.1 - 7e-37 127.2 0.0 1.4e-28 100.0 0.0 2.8 2 1 0 2 2 2 2 Rad9 OGG_N PF07934.12 RKO99781.1 - 9.2e-22 77.4 0.0 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 RKO99781.1 - 1.6e-09 38.2 0.0 3.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RKO99781.1 - 0.00029 20.6 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif F-box-like PF12937.7 RKO99782.1 - 0.017 15.0 0.4 0.017 15.0 0.4 2.2 2 0 0 2 2 2 0 F-box-like UCH PF00443.29 RKO99783.1 - 3.1e-25 89.1 0.0 7.1e-25 88.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKO99783.1 - 3.7e-05 23.5 0.0 0.13 11.8 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase SGL PF08450.12 RKO99784.1 - 0.021 14.4 0.0 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Pyr_redox_2 PF07992.14 RKO99785.1 - 7.6e-54 182.9 0.0 9.4e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO99785.1 - 2.5e-11 43.9 0.0 2.9e-09 37.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKO99785.1 - 0.00019 20.8 0.1 0.41 9.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RKO99785.1 - 0.0019 18.2 0.7 7.1 6.6 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 RKO99785.1 - 0.0063 16.1 0.4 6.1 6.3 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RKO99785.1 - 0.051 12.3 2.1 0.25 10.0 0.0 2.6 2 1 1 3 3 3 0 HI0933-like protein NIF PF03031.18 RKO99786.1 - 1.9e-11 44.0 0.0 1.7e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Ribosomal_L16 PF00252.18 RKO99787.1 - 1.2e-43 148.3 0.1 1.4e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e GCP_N_terminal PF17681.1 RKO99788.1 - 6.6e-72 242.7 0.0 2.1e-71 241.1 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RKO99788.1 - 6.8e-54 183.4 0.4 6.8e-54 183.4 0.4 2.0 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal TFIIA PF03153.13 RKO99788.1 - 2.7 7.9 6.6 3.8 7.4 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.21 RKO99789.1 - 4.1e-12 46.1 0.0 1.4e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RKO99789.1 - 0.00081 18.9 0.0 0.0025 17.3 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Trp_syntA PF00290.20 RKO99791.1 - 2e-85 285.8 0.0 3.4e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 RKO99791.1 - 1.2e-49 169.3 0.7 2.5e-49 168.3 0.7 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RhoGEF PF00621.20 RKO99792.1 - 6.5e-36 124.3 0.7 6.5e-36 124.3 0.7 2.2 3 0 0 3 3 3 1 RhoGEF domain SH3_9 PF14604.6 RKO99792.1 - 2e-16 59.5 0.1 2.8e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 RKO99792.1 - 5.8e-14 51.4 0.2 7.6e-07 28.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 RKO99792.1 - 8.4e-09 35.0 0.0 0.0045 16.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain XhlA PF10779.9 RKO99792.1 - 0.38 11.0 8.2 1.3 9.3 0.3 4.0 4 0 0 4 4 4 0 Haemolysin XhlA RXT2_N PF08595.11 RKO99794.1 - 1.9 8.5 13.1 4 7.5 13.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SGT1 PF07093.11 RKO99794.1 - 3 6.2 6.5 5.3 5.4 6.5 1.3 1 0 0 1 1 1 0 SGT1 protein DNA_pol_phi PF04931.13 RKO99794.1 - 6.9 4.6 22.2 12 3.8 22.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Activator_LAG-3 PF11498.8 RKO99795.1 - 6.9e-07 28.6 14.7 6.9e-07 28.6 14.7 2.9 3 0 0 3 3 2 1 Transcriptional activator LAG-3 DUF2722 PF10846.8 RKO99795.1 - 0.0088 15.0 22.1 0.071 12.0 13.8 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Cep57_CLD_2 PF14197.6 RKO99795.1 - 0.043 13.9 0.1 0.043 13.9 0.1 4.5 4 2 0 4 4 4 0 Centrosome localisation domain of PPC89 DDHD PF02862.17 RKO99795.1 - 0.19 11.9 8.6 3.9 7.6 0.4 2.6 2 0 0 2 2 2 0 DDHD domain YabA PF06156.13 RKO99795.1 - 0.29 11.8 21.0 29 5.4 5.7 4.7 3 2 1 4 4 4 0 Initiation control protein YabA Spt20 PF12090.8 RKO99795.1 - 0.39 10.3 36.9 0.011 15.3 17.0 2.3 2 0 0 2 2 2 0 Spt20 family V_ATPase_I PF01496.19 RKO99795.1 - 0.62 7.9 18.4 0.038 11.9 3.7 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spore_III_AF PF09581.10 RKO99795.1 - 3.7 7.6 14.7 0.06 13.4 2.6 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Syntaxin-18_N PF10496.9 RKO99795.1 - 6.7 7.0 11.9 1.4 9.2 0.1 3.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus EPL1 PF10513.9 RKO99795.1 - 7 7.0 11.4 3.8 7.9 4.0 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like SAGA-Tad1 PF12767.7 RKO99795.1 - 9.5 5.9 14.0 0.74 9.5 2.6 2.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit RVT_1 PF00078.27 RKO99796.1 - 1.4e-07 31.2 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 RKO99796.1 - 0.024 15.3 0.0 0.066 13.9 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DSHCT PF08148.12 RKO99797.1 - 3.8e-46 156.7 0.7 6.4e-46 156.0 0.7 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 RKO99797.1 - 1.3e-18 67.4 0.0 3.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO99797.1 - 3.5e-06 27.1 0.0 7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO99797.1 - 9.1e-06 26.0 0.0 3.1e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.6 RKO99797.1 - 0.0088 16.0 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain E1_dh PF00676.20 RKO99798.1 - 2.3e-96 322.3 0.3 2.7e-96 322.1 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RKO99798.1 - 0.0013 18.0 0.0 0.0051 16.1 0.0 1.9 3 0 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase Opi1 PF08618.10 RKO99799.1 - 3.7e-31 108.8 0.1 1.7e-21 77.0 0.2 5.2 4 1 1 5 5 5 3 Transcription factor Opi1 Perilipin PF03036.16 RKO99799.1 - 1.8e-07 30.6 0.0 3.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Perilipin family DUF1325 PF07039.11 RKO99800.1 - 1.1e-17 64.3 0.0 1.2e-15 57.7 0.0 2.9 1 1 0 1 1 1 1 SGF29 tudor-like domain TTL PF03133.15 RKO99801.1 - 4.6e-86 288.6 0.8 6.1e-86 288.2 0.8 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RKO99801.1 - 1e-09 38.0 0.4 0.00038 19.8 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RKO99801.1 - 1.8e-05 24.2 0.1 0.0087 15.3 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp PEN-2 PF10251.9 RKO99802.1 - 2.1e-23 82.6 1.7 2.3e-23 82.4 1.7 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF2569 PF10754.9 RKO99802.1 - 0.013 15.9 1.9 0.02 15.3 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) GTP_EFTU PF00009.27 RKO99803.1 - 1.5e-40 138.8 0.0 2.6e-40 138.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RKO99803.1 - 4e-21 74.8 0.0 1.2e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 RKO99803.1 - 4e-16 58.9 0.0 8.2e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 RKO99803.1 - 1.9e-12 47.8 0.3 3.2e-12 47.1 0.3 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 RKO99803.1 - 2.3e-10 40.7 0.0 6.2e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RKO99803.1 - 4.3e-05 23.5 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 RKO99803.1 - 4.7e-05 23.4 0.1 0.00011 22.2 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO99803.1 - 0.0046 16.5 0.2 0.12 11.9 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 RKO99803.1 - 0.026 14.1 0.0 0.063 12.9 0.0 1.6 1 1 0 1 1 1 0 Ras family Septin PF00735.18 RKO99803.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 RKO99803.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 RKO99803.1 - 0.21 11.0 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 RKO99803.1 - 0.22 11.8 0.0 1.1 9.5 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SWIB PF02201.18 RKO99804.1 - 1.3e-54 181.9 0.0 1.4e-26 92.2 0.0 2.3 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 RKO99804.1 - 6.4e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 DEK C terminal domain SAP30_Sin3_bdg PF13867.6 RKO99804.1 - 0.099 13.0 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3446 PF11928.8 RKO99804.1 - 0.14 12.4 6.3 0.3 11.4 6.3 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain SNF2_N PF00176.23 RKO99806.1 - 2.5e-54 184.3 0.0 4.3e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO99806.1 - 6.1e-19 68.4 0.1 6.9e-18 65.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO99806.1 - 3e-06 27.3 0.0 9.8e-06 25.7 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKO99806.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Phage_lysis PF03245.13 RKO99806.1 - 2.2 8.4 10.3 0.14 12.3 3.5 2.5 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein DnaJ PF00226.31 RKO99807.1 - 4.1e-16 58.8 0.0 7.3e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain IMUP PF15761.5 RKO99807.1 - 1.2 9.9 10.9 2.5 8.8 10.9 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Peptidase_M48_N PF16491.5 RKO99807.1 - 1.3 8.9 3.6 0.99 9.3 1.2 1.9 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices IPP-2 PF04979.14 RKO99808.1 - 1.3e-16 61.5 4.8 1.8e-11 44.9 4.8 2.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Cpn60_TCP1 PF00118.24 RKO99809.1 - 1.2e-162 542.0 3.0 1.3e-162 541.8 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 RKO99809.1 - 0.39 10.9 2.7 25 5.0 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Polysacc_deac_1 PF01522.21 RKO99811.1 - 1.7e-32 111.9 0.0 2.6e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 RKO99811.1 - 0.0097 15.1 0.0 0.018 14.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 nec1 PF10379.9 RKO99811.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Virulence protein nec1 WD40 PF00400.32 RKO99812.1 - 5.1e-35 118.9 20.6 9.2e-07 29.5 1.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99812.1 - 2.2e-18 66.3 0.0 0.044 14.1 0.0 7.0 3 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKO99812.1 - 2.6e-06 27.5 0.0 0.00037 20.4 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 RKO99812.1 - 2.2e-05 22.7 0.0 0.00012 20.3 0.0 2.0 1 1 1 2 2 2 1 IKI3 family Ge1_WD40 PF16529.5 RKO99812.1 - 0.00023 20.2 0.1 20 4.0 0.0 4.8 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 RKO99812.1 - 0.00094 19.1 5.4 5.8 7.0 0.1 6.3 6 1 0 6 6 6 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 RKO99812.1 - 0.028 14.4 2.4 9.4 6.1 0.1 3.8 2 2 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Frtz PF11768.8 RKO99812.1 - 0.2 9.9 0.0 6 5.1 0.0 2.6 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Uso1_p115_head PF04869.14 RKO99813.1 - 5e-34 117.9 0.0 1e-32 113.5 0.0 2.2 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 RKO99813.1 - 5.3e-07 30.1 2.7 9.3e-07 29.3 2.7 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT_2 PF13646.6 RKO99813.1 - 0.00061 20.1 3.1 0.24 11.8 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats Golgin_A5 PF09787.9 RKO99813.1 - 0.023 14.2 1.1 0.043 13.3 1.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 HEAT PF02985.22 RKO99813.1 - 0.028 14.7 8.5 0.091 13.1 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat RTP1_C1 PF10363.9 RKO99813.1 - 0.046 13.9 0.3 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 RKO99813.1 - 0.075 13.1 4.4 5.1 7.2 0.2 3.9 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Aminotran_3 PF00202.21 RKO99814.1 - 2.9e-117 391.8 0.0 3.3e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 RKO99814.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase TPR_19 PF14559.6 RKO99815.1 - 4.9e-15 55.8 27.2 0.00031 21.2 0.0 9.5 11 2 2 13 13 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99815.1 - 2.6e-10 39.6 18.1 0.6 10.4 0.0 10.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 RKO99815.1 - 3.7e-09 36.0 9.9 0.51 10.5 0.1 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO99815.1 - 2.8e-08 33.8 14.1 0.0004 20.5 1.6 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99815.1 - 2.7e-07 30.3 0.3 19 5.8 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKO99815.1 - 1.3e-05 24.7 9.7 0.61 10.0 0.0 6.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_3 PF07720.12 RKO99815.1 - 2.7e-05 24.1 2.5 0.001 19.0 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99815.1 - 4.2e-05 23.8 31.1 0.073 13.4 1.0 9.3 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99815.1 - 0.00027 21.5 1.5 0.00027 21.5 1.5 7.9 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99815.1 - 0.00063 19.9 0.1 12 6.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99815.1 - 0.00076 19.1 1.0 4.2 7.1 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 RKO99815.1 - 0.0018 18.9 32.1 0.11 13.4 0.3 8.9 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99815.1 - 9.8 7.1 18.9 11 6.9 0.1 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat DUF1977 PF09320.11 RKO99816.1 - 1.7e-22 79.6 0.1 2.8e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 RKO99816.1 - 8.2e-22 77.1 0.1 2.5e-21 75.6 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Pyr_redox_2 PF07992.14 RKO99817.1 - 6.6e-43 147.0 0.0 9.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO99817.1 - 1.7e-12 47.7 0.1 9e-10 39.0 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RKO99817.1 - 0.0001 22.1 0.3 0.018 14.6 0.0 3.0 1 1 2 3 3 3 1 FAD dependent oxidoreductase EF-hand_1 PF00036.32 RKO99817.1 - 0.00011 21.4 0.0 0.00035 19.9 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RKO99817.1 - 0.00055 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 RKO99817.1 - 0.0021 17.8 0.1 0.0056 16.5 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 RKO99817.1 - 0.0039 16.6 0.1 0.0083 15.6 0.1 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.6 RKO99817.1 - 0.023 14.0 0.1 5 6.3 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RKO99817.1 - 0.037 14.0 0.9 1.9 8.4 0.0 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding Caleosin PF05042.13 RKO99817.1 - 0.07 13.1 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Caleosin related protein Nop10p PF04135.12 RKO99818.1 - 3.4e-24 84.6 0.7 4.1e-24 84.4 0.7 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ubiq_cyt_C_chap PF03981.12 RKO99819.1 - 1.4e-24 86.8 0.3 2.2e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Nop PF01798.18 RKO99820.1 - 1.6e-64 217.6 0.0 1.8e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 RKO99820.1 - 6.1e-18 65.9 0.6 1.1e-17 65.1 0.6 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain tRNA_synthFbeta PF17759.1 RKO99821.1 - 1.8e-43 148.5 0.0 2.5e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 RKO99821.1 - 1.9e-31 108.1 0.2 4e-30 103.9 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 RKO99821.1 - 1.8e-22 79.8 0.1 3.8e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 RKO99821.1 - 1.9e-16 60.1 0.0 4.8e-14 52.4 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain GIT_SHD PF08518.11 RKO99821.1 - 0.0081 15.8 0.3 0.023 14.3 0.3 1.8 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT DUF2740 PF10872.8 RKO99821.1 - 0.031 14.2 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) DUF3375 PF11855.8 RKO99823.1 - 7.1e-05 21.9 8.2 0.00013 21.1 8.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) Mis14 PF08641.12 RKO99823.1 - 0.0066 16.8 0.8 0.017 15.4 0.2 2.0 2 1 1 3 3 3 1 Kinetochore protein Mis14 like PEP-utilizers PF00391.23 RKO99823.1 - 0.013 15.2 0.7 0.042 13.6 0.7 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain SR-25 PF10500.9 RKO99823.1 - 8.8 5.9 9.1 15 5.1 9.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DnaJ_C PF01556.18 RKO99824.1 - 1.9e-29 102.7 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKO99824.1 - 6.4e-18 64.6 0.3 1e-17 64.0 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Tam41_Mmp37 PF09139.11 RKO99825.1 - 8e-107 357.4 0.0 8.9e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial eIF3m_C_helix PF18005.1 RKO99827.1 - 0.088 12.5 0.5 0.088 12.5 0.5 2.5 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix Arnt_C PF18583.1 RKO99827.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.9 2 1 1 3 3 3 0 Aminoarabinose transferase C-terminal domain Filament PF00038.21 RKO99827.1 - 0.24 10.9 38.2 0.011 15.4 21.3 2.6 1 1 1 2 2 2 0 Intermediate filament protein Methyltransf_12 PF08242.12 RKO99828.1 - 7.3e-19 68.4 0.0 2.4e-17 63.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO99828.1 - 1.8e-16 60.4 0.0 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO99828.1 - 5.4e-15 55.9 0.0 1.7e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO99828.1 - 2.5e-12 47.3 0.0 6.3e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO99828.1 - 7.8e-11 42.0 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO99828.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 RKO99828.1 - 0.00038 19.7 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 RKO99828.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 RKO99828.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 RKO99828.1 - 0.15 11.6 0.0 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 RKO99828.1 - 0.17 11.5 0.0 0.48 10.0 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) SPO22 PF08631.10 RKO99829.1 - 6.7e-12 45.5 3.5 6.7e-12 45.5 3.5 4.5 4 1 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 RKO99829.1 - 0.00051 20.6 8.9 0.95 10.5 0.2 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99829.1 - 0.0019 18.8 5.6 0.0091 16.6 1.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RKO99829.1 - 0.015 15.8 5.6 0.51 10.9 0.6 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99829.1 - 0.27 11.6 4.7 0.15 12.3 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99829.1 - 0.76 10.0 6.5 0.66 10.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat His_Phos_2 PF00328.22 RKO99830.1 - 5.2e-72 243.3 0.0 6.9e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RKO99830.1 - 1.6e-35 121.1 0.0 3e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RKO99830.1 - 4.2e-07 29.8 0.0 7.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RKO99830.1 - 0.013 15.5 0.1 0.037 14.1 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain EZH2_N PF18601.1 RKO99830.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 EZH2 N-terminal domain Sensor_TM1 PF13755.6 RKO99831.1 - 0.92 9.3 3.3 6.3 6.6 0.2 3.2 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain vWA-TerF-like PF10138.9 RKO99831.1 - 0.99 9.5 22.1 0.98 9.5 1.0 6.1 2 2 5 8 8 8 0 vWA found in TerF C terminus CLCA PF08434.11 RKO99831.1 - 1.5 8.1 10.5 8.8 5.6 0.1 4.4 4 0 0 4 4 4 0 Calcium-activated chloride channel N terminal fn3 PF00041.21 RKO99832.1 - 2.9e-17 62.8 0.2 0.00032 21.0 0.0 4.8 4 0 0 4 4 4 3 Fibronectin type III domain Lebercilin PF15619.6 RKO99832.1 - 4.8e-08 32.9 16.8 4.8e-08 32.9 16.8 1.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Pur_ac_phosph_N PF16656.5 RKO99832.1 - 0.0018 18.8 0.1 18 6.0 0.0 3.7 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RKO99832.1 - 0.005 17.2 1.9 5 7.6 0.0 3.9 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) TRAF_BIRC3_bd PF16673.5 RKO99832.1 - 0.027 14.2 0.8 0.027 14.2 0.8 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF641 PF04859.12 RKO99832.1 - 0.66 10.3 12.1 2.8 8.3 4.0 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF1192 PF06698.11 RKO99832.1 - 1.3 9.1 5.6 13 5.9 1.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 RKO99832.1 - 1.9 9.0 16.3 0.18 12.3 6.9 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 RKO99832.1 - 2.9 6.4 5.7 1.1 7.8 3.2 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMCO5 PF14992.6 RKO99832.1 - 4.7 6.7 8.7 0.65 9.5 3.6 1.9 1 1 1 2 2 2 0 TMCO5 family RNA_pol PF00940.19 RKO99833.1 - 5.7e-156 519.5 0.0 8.9e-156 518.9 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 RKO99833.1 - 3.8e-55 187.6 0.1 6.1e-55 186.9 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal HALZ PF02183.18 RKO99834.1 - 0.11 12.7 1.4 0.17 12.1 1.4 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 RKO99834.1 - 0.26 11.5 0.4 0.4 10.9 0.4 1.2 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Csm1 PF12539.8 RKO99835.1 - 6.5e-06 26.7 0.0 0.027 15.1 0.0 2.5 2 0 0 2 2 2 2 Chromosome segregation protein Csm1/Pcs1 Atg14 PF10186.9 RKO99835.1 - 0.11 11.6 28.8 1 8.4 7.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5094 PF17015.5 RKO99835.1 - 0.2 11.7 2.8 0.24 11.5 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5094) CDP-OH_P_transf PF01066.21 RKO99836.1 - 3.6e-13 50.1 0.5 3.6e-13 50.1 0.5 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PTPLA PF04387.14 RKO99836.1 - 0.086 12.6 1.3 0.14 11.8 0.3 1.7 1 1 1 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA Homeodomain PF00046.29 RKO99837.1 - 1.9e-19 69.2 0.6 2.1e-19 69.1 0.6 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RKO99837.1 - 0.0089 15.9 0.2 0.042 13.8 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain Sigma70_r4_2 PF08281.12 RKO99837.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.6 RKO99837.1 - 0.12 12.5 3.4 0.51 10.5 0.6 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain BTRD1 PF17660.1 RKO99837.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 DUF4874 PF16173.5 RKO99838.1 - 5.7e-13 48.8 0.0 8.3e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) MOFRL PF05161.13 RKO99839.1 - 0.46 10.7 2.7 0.28 11.4 0.2 1.9 2 0 0 2 2 2 0 MOFRL family zf-DNL PF05180.12 RKO99840.1 - 1.7e-28 98.4 0.1 1.9e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 DNL zinc finger ZZ PF00569.17 RKO99840.1 - 0.077 12.8 2.4 7.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type PHD PF00628.29 RKO99840.1 - 0.31 10.9 3.5 1.3 8.9 3.5 1.8 1 1 1 2 2 2 0 PHD-finger PIG-S PF10510.9 RKO99841.1 - 8.7e-86 288.8 1.5 9.7e-86 288.6 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein LSM PF01423.22 RKO99842.1 - 3.6e-14 52.2 0.1 4.5e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO99842.1 - 0.021 15.0 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain P2_N PF18628.1 RKO99842.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain BRX PF08381.11 RKO99843.1 - 0.58 9.6 3.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 UDPGP PF01704.18 RKO99844.1 - 1.4e-56 191.9 0.0 1.8e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 RKO99844.1 - 0.0052 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain GAS PF13851.6 RKO99846.1 - 3 7.2 11.8 0.48 9.7 5.6 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SAM_2 PF07647.17 RKO99847.1 - 1.5e-13 50.6 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RKO99847.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 RKO99847.1 - 1e-09 38.1 0.2 1.6e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO99847.1 - 1.5e-08 34.1 0.2 3.2e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKO99847.1 - 2.1e-07 30.5 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.16 RKO99847.1 - 0.042 13.8 0.0 0.18 11.8 0.1 2.0 2 1 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 RKO99847.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Per1 PF04080.13 RKO99848.1 - 3e-82 276.2 8.2 3.6e-82 276.0 8.2 1.0 1 0 0 1 1 1 1 Per1-like family DUF4199 PF13858.6 RKO99848.1 - 3.7 7.9 5.4 4 7.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Cyclin_N PF00134.23 RKO99849.1 - 1.1e-13 51.0 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain BUD22 PF09073.10 RKO99849.1 - 0.07 12.5 13.2 0.11 11.9 13.2 1.2 1 0 0 1 1 1 0 BUD22 Peptidase_M48_N PF16491.5 RKO99850.1 - 1.2e-60 204.5 3.9 1.2e-60 204.5 3.9 1.8 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 RKO99850.1 - 5.3e-42 143.8 0.0 8.3e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 RKO99850.1 - 0.0017 18.1 2.2 0.0056 16.4 2.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) GtrA PF04138.14 RKO99850.1 - 0.0088 16.3 4.9 0.22 11.8 3.1 2.7 2 0 0 2 2 2 1 GtrA-like protein Pept_tRNA_hydro PF01195.19 RKO99851.1 - 7.2e-34 117.2 0.0 1.3e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase Spt20 PF12090.8 RKO99851.1 - 5.9 6.4 8.6 9.1 5.8 8.6 1.2 1 0 0 1 1 1 0 Spt20 family APH PF01636.23 RKO99852.1 - 1.6e-37 129.7 2.6 2.5e-37 129.1 2.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RKO99852.1 - 7.3e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 RKO99852.1 - 0.0038 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 RKO99852.1 - 0.25 10.2 0.0 0.35 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) KxDL PF10241.9 RKO99853.1 - 0.22 11.8 0.1 0.51 10.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein RhoGAP PF00620.27 RKO99854.1 - 8.3e-34 116.6 0.0 1.8e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Nore1-SARAH PF16517.5 RKO99854.1 - 0.31 11.0 1.4 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Rad1 PF02144.16 RKO99858.1 - 2.8e-39 134.9 0.0 3.4e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Pkinase PF00069.25 RKO99859.1 - 4.1e-64 216.5 0.0 4.6e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99859.1 - 9.8e-46 156.1 0.0 1.2e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO99859.1 - 2.6e-05 23.2 0.0 3.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKO99859.1 - 0.0091 15.3 0.0 0.033 13.5 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKO99859.1 - 0.18 10.7 0.0 7.3 5.4 0.0 2.1 1 1 0 2 2 2 0 Haspin like kinase domain COPIIcoated_ERV PF07970.12 RKO99861.1 - 1.3e-40 139.6 0.5 1.9e-40 139.0 0.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RKO99861.1 - 1.6e-19 70.1 0.7 5.3e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Mnd1 PF03962.15 RKO99862.1 - 4.4e-29 100.6 0.9 1e-28 99.4 0.2 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 RKO99862.1 - 2.1e-18 66.2 3.2 6.1e-18 64.7 0.5 2.5 1 1 1 2 2 2 1 Leucine zipper with capping helix domain DUF3375 PF11855.8 RKO99862.1 - 0.0058 15.6 0.7 0.0077 15.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) Leu_zip PF15294.6 RKO99862.1 - 0.011 15.2 2.2 0.019 14.5 2.2 1.3 1 0 0 1 1 1 0 Leucine zipper GntR PF00392.21 RKO99862.1 - 0.036 13.7 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF5457 PF17540.2 RKO99862.1 - 0.083 13.0 0.9 0.18 11.9 0.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5457) LMP PF04778.12 RKO99862.1 - 0.11 12.4 6.0 0.04 13.8 3.5 1.5 2 0 0 2 2 2 0 LMP repeated region TBPIP PF07106.13 RKO99862.1 - 0.12 12.4 0.1 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain SMBP PF16785.5 RKO99862.1 - 0.18 12.0 2.2 0.32 11.2 2.2 1.3 1 0 0 1 1 1 0 Small metal-binding protein DivIC PF04977.15 RKO99862.1 - 0.74 9.6 6.3 1.1 9.0 0.8 2.5 1 1 1 2 2 2 0 Septum formation initiator Nckap1 PF09735.9 RKO99863.1 - 6e-142 474.9 0.0 7.3e-142 474.6 0.0 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Glyco_hydro_76 PF03663.14 RKO99865.1 - 4.1e-43 148.3 3.7 4.9e-43 148.0 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 RKO99865.1 - 0.023 13.8 3.8 1.2 8.2 0.0 3.3 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 DUF3915 PF13054.6 RKO99867.1 - 0.14 12.2 23.0 0.6 10.1 6.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RSB_motif PF16294.5 RKO99867.1 - 3.5 8.0 25.3 8.1 6.8 12.1 2.6 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif CAP_GLY PF01302.25 RKO99870.1 - 1.8e-13 50.3 0.0 5.7e-13 48.7 0.0 1.9 2 1 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 RKO99870.1 - 1.8e-10 40.9 0.8 0.022 15.2 0.2 4.0 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO99870.1 - 3.1e-07 30.0 7.0 0.053 13.3 0.1 3.9 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 RKO99870.1 - 9.6e-05 21.9 0.9 0.0013 18.3 0.3 2.6 2 1 1 3 3 3 1 Leucine-rich repeat TFIIF_beta PF02270.15 RKO99871.1 - 4.7e-25 87.5 0.5 7.5e-25 86.9 0.5 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 RKO99871.1 - 1.4e-22 80.8 0.0 2.1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus bZIP_1 PF00170.21 RKO99872.1 - 7.3e-10 38.8 15.2 1.6e-09 37.7 15.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2722 PF10846.8 RKO99872.1 - 1.2e-06 27.8 7.3 1.8e-06 27.2 7.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) EF-hand_6 PF13405.6 RKO99873.1 - 0.18 11.8 0.0 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 RKO99873.1 - 0.21 11.4 0.2 1.1 9.1 0.0 2.2 3 0 0 3 3 3 0 EF-hand domain pair Chorion_3 PF05387.11 RKO99873.1 - 1.4 8.5 6.7 0.65 9.6 0.4 2.1 2 0 0 2 2 2 0 Chorion family 3 Mito_carr PF00153.27 RKO99874.1 - 3.2e-68 225.7 1.1 5.4e-22 77.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIA PF03153.13 RKO99875.1 - 0.0005 20.2 1.5 0.0005 20.2 1.5 3.5 2 1 2 4 4 4 1 Transcription factor IIA, alpha/beta subunit ANF_receptor PF01094.28 RKO99876.1 - 1.4e-46 159.2 0.3 2.2e-46 158.6 0.0 1.4 2 0 0 2 2 2 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 RKO99876.1 - 4.5e-30 105.5 0.1 7e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 RKO99876.1 - 1.4e-29 103.6 17.2 1.4e-29 103.6 17.2 1.5 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Mit_KHE1 PF10173.9 RKO99877.1 - 1.3e-41 142.8 0.1 1.5e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Sec7 PF01369.20 RKO99878.1 - 2e-70 236.2 0.0 4.6e-70 235.0 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RKO99878.1 - 5.4e-33 114.1 3.8 1.3e-32 112.9 0.1 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 RKO99878.1 - 1.6e-28 98.4 8.9 5.2e-28 96.7 0.1 5.2 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 RKO99878.1 - 7e-23 81.2 10.6 4.7e-22 78.5 3.5 3.4 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 Ipi1_N PF12333.8 RKO99878.1 - 0.06 13.9 0.0 2.6 8.7 0.0 3.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 RKO99878.1 - 0.13 12.6 0.1 40 4.8 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Symplekin_C PF12295.8 RKO99878.1 - 3.5 7.7 9.3 1.4 9.0 0.0 4.0 5 0 0 5 5 5 0 Symplekin tight junction protein C terminal SH3_9 PF14604.6 RKO99879.1 - 4.4e-08 32.9 0.1 1.4e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 RKO99879.1 - 3e-05 23.6 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain stn_TNFRSF12A PF12191.8 RKO99879.1 - 0.093 13.0 3.2 0.13 12.5 0.1 2.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Spt20 PF12090.8 RKO99879.1 - 0.39 10.3 2.5 0.61 9.7 2.5 1.2 1 0 0 1 1 1 0 Spt20 family RabGAP-TBC PF00566.18 RKO99880.1 - 4.7e-12 46.0 0.6 4.7e-12 46.0 0.6 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ANAPC4_WD40 PF12894.7 RKO99880.1 - 0.017 15.4 0.9 1.4 9.3 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FAM183 PF14886.6 RKO99881.1 - 1.1e-06 29.3 0.1 9e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 FAM183A and FAM183B related Peptidase_M18 PF02127.15 RKO99883.1 - 3.2e-168 560.0 0.0 3.6e-168 559.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 RKO99883.1 - 8.2e-06 25.0 0.4 0.004 16.2 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase LSM PF01423.22 RKO99884.1 - 2.4e-18 65.6 0.1 3.7e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain 2-ph_phosp PF04029.14 RKO99884.1 - 0.0068 15.6 0.0 0.0083 15.3 0.0 1.1 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase Propep_M14 PF02244.16 RKO99884.1 - 0.15 12.5 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide NOA36 PF06524.12 RKO99885.1 - 5.8 6.1 5.3 8.1 5.7 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 RKO99885.1 - 6.4 6.4 7.0 9.7 5.8 7.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Swi5 PF07061.11 RKO99886.1 - 5.6e-16 58.4 0.1 6.3e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 Swi5 Big_9 PF17963.1 RKO99887.1 - 0.11 13.2 0.0 0.16 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig domain CDC45 PF02724.14 RKO99888.1 - 0.16 10.2 4.2 0.28 9.4 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RmuC PF02646.16 RKO99888.1 - 0.19 10.8 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 RmuC family SAPS PF04499.15 RKO99888.1 - 2.5 6.8 3.3 4 6.1 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ras PF00071.22 RKO99889.1 - 5e-46 156.3 0.0 5.7e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO99889.1 - 1.2e-29 102.9 0.0 1.6e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO99889.1 - 7e-13 48.4 0.0 8.1e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO99889.1 - 2.1e-05 24.1 0.1 0.00043 19.9 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RKO99889.1 - 3.7e-05 23.2 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO99889.1 - 7.3e-05 22.8 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKO99889.1 - 0.0046 16.9 0.0 0.67 9.8 0.0 2.4 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 RKO99889.1 - 0.0088 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 RKO99889.1 - 0.03 14.1 0.0 0.23 11.2 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GAPES3 PF17154.4 RKO99889.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain HIG_1_N PF04588.13 RKO99890.1 - 0.0019 18.4 0.6 0.043 14.0 0.2 2.3 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ArsP_1 PF03773.13 RKO99890.1 - 0.073 12.2 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted permease ENOD93 PF03386.14 RKO99890.1 - 0.074 12.9 0.1 0.074 12.9 0.1 2.0 3 0 0 3 3 3 0 Early nodulin 93 ENOD93 protein Peptidase_S9 PF00326.21 RKO99891.1 - 1.6e-06 27.8 0.0 3.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RKO99891.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKO99891.1 - 0.014 14.7 0.0 0.079 12.2 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Kri1_C PF12936.7 RKO99893.1 - 1.2e-17 63.8 0.1 1.2e-17 63.8 0.1 3.4 4 1 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 RKO99893.1 - 7.9e-17 61.7 9.2 7.9e-17 61.7 9.2 5.1 4 1 1 5 5 5 1 KRI1-like family HSP90 PF00183.18 RKO99894.1 - 3.5e-233 775.2 22.9 4.4e-233 774.8 22.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RKO99894.1 - 4.4e-15 56.2 0.2 8.1e-15 55.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RKO99894.1 - 3.9e-11 42.9 0.3 1.1e-10 41.5 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 RKO99894.1 - 0.0046 17.0 1.1 0.0082 16.2 0.0 1.9 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN SAM_3 PF18016.1 RKO99894.1 - 0.042 13.6 0.2 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SNARE PF05739.19 RKO99895.1 - 0.0086 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 SNARE domain Sigma70_ner PF04546.13 RKO99895.1 - 0.015 15.2 1.0 0.018 14.9 0.3 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region THOC7 PF05615.13 RKO99895.1 - 0.022 15.0 1.2 0.04 14.2 0.0 1.9 2 1 0 2 2 2 0 Tho complex subunit 7 DUF3246 PF11596.8 RKO99895.1 - 0.026 14.0 3.2 0.038 13.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 RKO99895.1 - 0.053 13.3 1.2 0.085 12.6 1.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RKO99895.1 - 0.61 9.4 2.3 0.84 8.9 2.3 1.3 1 0 0 1 1 1 0 NOA36 protein SlyX PF04102.12 RKO99895.1 - 1.5 9.5 18.2 0.36 11.5 2.1 3.5 4 0 0 4 4 4 0 SlyX DNA_pol_phi PF04931.13 RKO99895.1 - 2.6 6.0 9.8 3.6 5.6 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PIG-Y PF15159.6 RKO99896.1 - 1.1e-07 32.7 0.2 1.9e-07 31.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF5539 PF17693.1 RKO99896.1 - 3 7.4 10.8 0.067 12.8 4.7 1.3 2 0 0 2 2 2 0 Family of unknown function (DUF5539) GDPD PF03009.17 RKO99897.1 - 3.5e-16 59.7 0.0 1.8e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SAC3_GANP PF03399.16 RKO99898.1 - 1.8e-19 70.2 0.3 1.9e-17 63.6 0.3 2.0 1 1 0 1 1 1 1 SAC3/GANP family Cyclin PF08613.11 RKO99899.1 - 3e-06 27.7 0.0 9.9e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin AAA PF00004.29 RKO99903.1 - 7.7e-43 146.1 0.0 1.3e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RKO99903.1 - 1.3e-10 41.0 0.1 2.9e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RKO99903.1 - 2.2e-09 37.0 0.7 3.9e-09 36.2 0.7 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RKO99903.1 - 7.4e-07 29.4 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RKO99903.1 - 6.3e-06 26.5 0.1 0.002 18.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RKO99903.1 - 3.7e-05 23.0 0.0 6.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 RKO99903.1 - 4.2e-05 23.6 0.1 0.00031 20.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO99903.1 - 5.5e-05 23.6 0.1 0.0018 18.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RKO99903.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 RKO99903.1 - 0.0013 19.3 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKO99903.1 - 0.002 18.4 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RKO99903.1 - 0.0028 17.4 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 RKO99903.1 - 0.0054 16.9 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RKO99903.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RKO99903.1 - 0.0069 16.8 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.13 RKO99903.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 RKO99903.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 RKO99903.1 - 0.026 13.8 0.1 0.47 9.8 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.11 RKO99903.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 RKO99903.1 - 0.03 13.8 0.1 0.091 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 RKO99903.1 - 0.036 13.8 0.8 0.078 12.7 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKO99903.1 - 0.043 13.3 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RKO99903.1 - 0.053 13.1 0.6 0.4 10.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 RKO99903.1 - 0.067 12.9 0.2 0.22 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO99903.1 - 0.082 12.8 0.0 0.6 10.0 0.0 2.2 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 RKO99903.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 RKO99903.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NB-ARC PF00931.22 RKO99903.1 - 0.14 11.4 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 RKO99903.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 RKO99903.1 - 0.14 12.6 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 RKO99903.1 - 0.16 11.7 0.0 0.6 9.8 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 RKO99903.1 - 0.8 9.6 3.5 1.8 8.4 0.0 2.8 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Methyltransf_8 PF05148.15 RKO99904.1 - 9.3e-64 215.3 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 RKO99904.1 - 2.5e-06 28.0 0.0 7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO99904.1 - 0.00024 21.7 0.0 0.00078 20.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO99904.1 - 0.025 14.4 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 RKO99904.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DnaJ_C PF01556.18 RKO99905.1 - 8.3e-40 136.3 0.0 1.1e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKO99905.1 - 3e-24 84.9 2.2 4.7e-24 84.3 2.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RKO99905.1 - 2.9e-14 53.2 17.9 5.5e-14 52.3 17.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 RKO99905.1 - 0.05 13.6 11.3 0.97 9.5 1.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RKO99905.1 - 1.6 8.8 14.9 54 3.9 4.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon Anti-TRAP PF15777.5 RKO99905.1 - 5 7.2 19.6 1.9 8.5 3.6 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein IF-2B PF01008.17 RKO99906.1 - 1.1e-65 221.7 0.0 1.2e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ECH_1 PF00378.20 RKO99907.1 - 4.7e-48 163.7 0.5 1.4e-44 152.4 0.5 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKO99907.1 - 2.6e-28 99.5 0.2 3.3e-25 89.3 0.1 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HAD_SAK_1 PF10307.9 RKO99907.1 - 0.23 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins VHS PF00790.19 RKO99908.1 - 2.5e-33 114.9 0.1 2.1e-32 111.9 0.0 2.1 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 RKO99908.1 - 2.2e-17 63.0 10.1 4.5e-17 61.9 10.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RKO99908.1 - 0.00048 20.3 3.7 0.00092 19.4 3.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 RKO99908.1 - 0.047 13.7 12.1 4.3 7.4 2.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 RKO99908.1 - 2.7 8.3 9.5 1.9 8.8 7.7 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Cullin PF00888.22 RKO99909.1 - 1.8e-108 363.8 0.0 2.5e-88 297.3 0.0 2.2 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 RKO99909.1 - 6.2e-20 71.0 0.3 1.4e-19 69.9 0.3 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain PBP1_TM PF14812.6 RKO99909.1 - 1.7 9.1 10.8 0.14 12.5 4.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dzip-like_N PF13815.6 RKO99910.1 - 1.3e-21 76.8 0.2 1.3e-21 76.8 0.2 2.6 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Atg14 PF10186.9 RKO99910.1 - 0.0073 15.4 2.9 0.028 13.5 0.1 2.6 2 1 1 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2 PF00096.26 RKO99910.1 - 0.0093 16.4 2.0 0.027 14.9 2.0 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type UPF0184 PF03670.13 RKO99910.1 - 0.089 13.2 0.5 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) ARS2 PF04959.13 RKO99910.1 - 0.089 13.2 0.1 0.27 11.6 0.1 1.9 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2H2_4 PF13894.6 RKO99910.1 - 0.09 13.7 1.8 0.26 12.2 1.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger TAL_effector PF03377.13 RKO99910.1 - 0.31 11.4 1.8 1.3 9.4 0.8 2.3 2 0 0 2 2 2 0 TAL effector repeat GrpE PF01025.19 RKO99910.1 - 0.71 9.5 10.4 0.41 10.3 5.5 2.3 2 0 0 2 2 2 0 GrpE PTP_N PF12453.8 RKO99911.1 - 0.52 10.1 2.0 0.97 9.2 2.0 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Dus PF01207.17 RKO99912.1 - 4e-63 213.4 0.0 4.7e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RKO99912.1 - 0.0044 16.5 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 RKO99912.1 - 0.0072 15.7 0.1 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Thiamine monophosphate synthase ScsC_N PF18312.1 RKO99912.1 - 0.1 12.4 2.6 0.18 11.6 0.0 2.5 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain RXT2_N PF08595.11 RKO99914.1 - 3.3e-11 43.5 1.4 4.6e-09 36.5 0.2 2.1 1 1 1 2 2 2 2 RXT2-like, N-terminal IFT43 PF15305.6 RKO99915.1 - 0.0049 17.0 0.1 0.25 11.5 0.0 2.5 2 1 0 2 2 2 2 Intraflagellar transport protein 43 Amastin PF07344.11 RKO99916.1 - 0.015 15.2 3.5 0.015 15.2 3.5 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein PGM_PMM_I PF02878.16 RKO99917.1 - 1.6e-34 118.6 0.1 5.7e-34 116.8 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 RKO99917.1 - 3.5e-19 69.3 0.0 9.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 RKO99917.1 - 3.1e-14 53.1 0.1 7.1e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 RKO99917.1 - 3.1e-06 27.3 0.0 8.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RTC_insert PF05189.13 RKO99917.1 - 0.027 15.0 0.0 4.3 7.9 0.0 2.8 2 0 0 2 2 2 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4129 PF13559.6 RKO99917.1 - 0.25 11.6 2.5 7.7 6.9 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) TPR_2 PF07719.17 RKO99918.1 - 3.3e-15 54.9 5.9 3.3e-05 23.6 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RKO99918.1 - 9.8e-15 53.7 2.4 0.00029 20.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKO99918.1 - 1.5e-12 47.0 0.4 1.6e-05 24.5 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_19 PF14559.6 RKO99918.1 - 4.8e-10 39.8 5.1 1.1e-08 35.4 1.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99918.1 - 5.5e-10 38.7 0.6 0.0037 17.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKO99918.1 - 2.4e-09 37.2 8.8 0.075 13.9 0.5 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99918.1 - 4e-08 33.8 7.5 1.4e-06 28.8 1.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99918.1 - 5.3e-08 33.0 8.3 0.00017 21.8 4.8 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKO99918.1 - 1.8e-05 24.8 2.6 0.077 13.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO99918.1 - 2e-05 24.7 2.7 0.037 14.2 1.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO99918.1 - 0.0003 20.9 5.2 0.026 14.7 3.5 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RKO99918.1 - 0.00046 20.0 4.2 0.026 14.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKO99918.1 - 0.00081 18.7 2.7 0.15 11.2 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 RKO99918.1 - 0.0011 19.4 9.7 1.6 9.6 2.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99918.1 - 0.0013 19.3 7.3 0.95 10.2 0.1 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 RKO99918.1 - 0.003 17.3 1.3 0.0061 16.3 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 RKO99918.1 - 0.0073 16.7 5.2 0.04 14.3 2.2 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 RKO99918.1 - 0.0097 16.2 1.1 0.033 14.5 0.3 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 RKO99918.1 - 0.12 11.9 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR MIT PF04212.18 RKO99918.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.9 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 RKO99918.1 - 0.36 10.1 8.4 9.9 5.4 0.1 3.1 1 1 2 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 RKO99918.1 - 1.4 8.9 6.4 3.4 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3377 PF11857.8 RKO99919.1 - 0.019 14.9 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RAMP PF04901.13 RKO99919.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Receptor activity modifying family DUF3824 PF12868.7 RKO99919.1 - 0.4 11.3 8.2 0.039 14.6 3.1 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Ribosomal_60s PF00428.19 RKO99919.1 - 1.5 9.5 13.0 0.063 13.9 5.8 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Arrestin_N PF00339.29 RKO99920.1 - 0.00054 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 RKO99921.1 - 7.5e-05 23.4 1.7 2.5 9.1 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2_C PF09173.11 RKO99922.1 - 4.4e-38 129.4 0.2 1.1e-37 128.2 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 RKO99922.1 - 3.1e-24 85.6 0.9 2.4e-23 82.7 0.9 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RKO99922.1 - 3.7e-11 43.2 1.9 3.3e-10 40.2 0.2 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 RKO99922.1 - 0.00043 20.2 0.7 0.0051 16.7 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RKO99922.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 RKO99922.1 - 0.0025 17.8 0.2 0.0068 16.4 0.2 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 RKO99922.1 - 0.099 12.7 0.0 0.43 10.6 0.0 2.1 2 1 1 3 3 3 0 Dynamin family DUF3750 PF12570.8 RKO99923.1 - 0.037 14.7 0.4 0.041 14.6 0.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3750) Matrilin_ccoil PF10393.9 RKO99924.1 - 0.23 11.3 0.3 0.34 10.8 0.3 1.2 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin UBX PF00789.20 RKO99925.1 - 0.034 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 UBX domain TUG-UBL1 PF11470.8 RKO99926.1 - 3.1e-11 43.3 0.0 1.3e-08 35.0 0.0 2.6 2 0 0 2 2 2 2 TUG ubiquitin-like domain Mito_carr PF00153.27 RKO99927.1 - 4.6e-61 202.8 8.4 3.3e-22 78.2 0.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RKO99927.1 - 0.054 12.6 0.1 8.6 5.4 0.0 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF4235 PF14019.6 RKO99927.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) RasGEF PF00617.19 RKO99928.1 - 1.6e-13 51.2 0.0 3.4e-13 50.2 0.0 1.5 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RKO99928.1 - 0.00029 21.0 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF3453 PF11935.8 RKO99929.1 - 1.1e-20 74.3 0.0 2.3e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HMG_box PF00505.19 RKO99930.1 - 1.1e-12 48.1 1.3 3.8e-10 40.0 0.1 3.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO99930.1 - 4.9e-07 30.2 0.4 2.1e-06 28.2 0.1 2.3 3 0 0 3 3 3 1 HMG-box domain Glyco_transf_20 PF00982.21 RKO99931.1 - 2.7e-157 524.3 0.0 3.5e-157 523.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RKO99931.1 - 6.1e-30 104.1 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase B-block_TFIIIC PF04182.12 RKO99932.1 - 2e-11 43.9 0.1 7.9e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 RKO99932.1 - 4.9e-06 26.0 0.0 0.064 12.8 0.0 2.9 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding MarR PF01047.22 RKO99932.1 - 0.087 12.8 0.0 8.2 6.4 0.0 3.4 3 0 0 3 3 3 0 MarR family HTH_5 PF01022.20 RKO99932.1 - 0.17 11.7 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF4660 PF15559.6 RKO99932.1 - 0.22 11.9 1.9 7.3 7.0 0.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Voltage_CLC PF00654.20 RKO99933.1 - 1.6e-80 271.0 30.5 6.2e-80 269.1 26.4 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 RKO99933.1 - 3.1e-05 24.3 0.5 0.064 13.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain FR47 PF08445.10 RKO99934.1 - 1.9e-13 50.1 0.1 3.6e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RKO99934.1 - 1.5e-09 38.2 0.2 2.4e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKO99934.1 - 1.5e-09 38.1 0.1 2.2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RKO99934.1 - 2e-09 37.5 0.1 3.1e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RKO99934.1 - 0.0002 21.4 0.1 0.00033 20.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 RKO99934.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 RKO99934.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase SCA7 PF08313.12 RKO99935.1 - 0.0001 22.1 0.6 0.00052 19.9 0.6 2.1 1 1 0 1 1 1 1 SCA7, zinc-binding domain HSF_DNA-bind PF00447.17 RKO99937.1 - 2.5e-33 114.6 2.0 2.5e-33 114.6 2.0 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding Acetyltransf_9 PF13527.7 RKO99937.1 - 0.041 13.9 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Baculo_PEP_C PF04513.12 RKO99937.1 - 0.043 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-ZPR1 PF03367.13 RKO99937.1 - 0.065 13.1 0.2 0.098 12.5 0.2 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain zf-RING_2 PF13639.6 RKO99939.1 - 8.3e-07 29.2 11.5 1.2e-06 28.7 11.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 RKO99939.1 - 2e-05 24.6 6.4 5.6e-05 23.1 6.5 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 RKO99939.1 - 0.00032 20.8 8.0 0.00099 19.2 8.0 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 RKO99939.1 - 0.0004 20.6 14.4 0.002 18.4 14.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 RKO99939.1 - 0.13 12.1 7.9 0.18 11.6 7.9 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 RKO99939.1 - 0.15 12.2 9.4 0.31 11.2 9.4 1.6 1 1 0 1 1 1 0 RING-variant domain GAGA PF09237.11 RKO99939.1 - 0.31 10.9 4.9 1.7 8.5 0.6 2.4 2 0 0 2 2 2 0 GAGA factor Zn_ribbon_17 PF17120.5 RKO99939.1 - 0.45 10.2 7.6 0.8 9.4 7.4 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 RKO99939.1 - 0.55 10.1 9.8 1.8 8.5 9.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 RKO99939.1 - 0.78 10.1 10.6 0.48 10.8 7.8 1.9 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_2 PF13923.6 RKO99939.1 - 1.8 8.5 13.6 4.8 7.1 13.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 RKO99940.1 - 0.12 10.6 2.4 0.19 10.0 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4381 PF14316.6 RKO99941.1 - 0.19 11.9 2.7 10 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) UDPG_MGDP_dh_N PF03721.14 RKO99942.1 - 2.9e-61 206.3 0.0 7.2e-61 205.0 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 RKO99942.1 - 2e-33 114.9 0.1 7.4e-33 113.1 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 RKO99942.1 - 7.6e-31 106.2 0.0 1.6e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 RKO99942.1 - 0.0031 17.7 0.0 0.087 13.0 0.0 2.6 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RKO99942.1 - 0.0082 16.7 0.1 6.6 7.4 0.0 3.5 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 RKO99942.1 - 0.014 15.5 0.0 5.1 7.2 0.0 3.2 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain BMC PF00936.19 RKO99942.1 - 0.035 14.1 1.3 0.1 12.6 1.3 1.7 1 0 0 1 1 1 0 BMC domain Kinesin PF00225.23 RKO99943.1 - 7.3e-94 314.4 0.1 8.3e-94 314.2 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO99943.1 - 1.9e-16 60.3 0.0 3.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 RKO99943.1 - 0.11 12.4 0.1 0.2 11.7 0.1 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zw10 PF06248.13 RKO99944.1 - 5.6e-05 21.9 0.5 8.2e-05 21.4 0.5 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 VEFS-Box PF09733.9 RKO99944.1 - 0.00028 20.7 0.7 0.00056 19.7 0.7 1.5 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Vps51 PF08700.11 RKO99944.1 - 0.00041 20.4 0.3 0.0021 18.1 0.3 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 RKO99944.1 - 0.0044 17.1 3.2 0.011 15.8 3.2 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 RKO99944.1 - 0.015 15.1 1.4 0.023 14.5 1.4 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Sec8_exocyst PF04048.14 RKO99944.1 - 0.052 13.4 3.1 0.1 12.5 3.1 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 RKO99944.1 - 0.1 12.7 4.1 0.24 11.6 3.7 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 NOA36 PF06524.12 RKO99944.1 - 0.11 11.8 1.2 0.17 11.2 1.2 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 RKO99944.1 - 0.41 11.1 7.3 0.13 12.7 4.1 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 RKO99944.1 - 0.42 10.6 7.6 29 4.7 8.7 2.8 2 1 0 2 2 2 0 RXT2-like, N-terminal Aminotran_1_2 PF00155.21 RKO99945.1 - 1.3e-50 172.7 0.0 1.5e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RHH_1 PF01402.21 RKO99946.1 - 0.39 10.7 0.2 0.39 10.7 0.2 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Nbl1_Borealin_N PF10444.9 RKO99946.1 - 1 9.1 5.8 0.3 10.7 1.5 2.4 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal DUF4164 PF13747.6 RKO99946.1 - 2.4 8.5 6.0 2.8 8.3 3.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Ribophorin_II PF05817.14 RKO99947.1 - 5.8e-14 51.6 1.0 1.4e-13 50.3 0.1 1.8 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit Ribophorin II TMEMspv1-c74-12 PF11044.8 RKO99947.1 - 0.7 9.9 1.6 1.4 9.0 1.6 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein XPG_N PF00752.17 RKO99948.1 - 3.8e-24 85.1 0.0 6.7e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 RKO99948.1 - 1.5e-21 76.5 0.0 2.2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 RKO99948.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 RKO99948.1 - 0.027 14.6 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat 5_3_exonuc PF01367.20 RKO99948.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_14 PF13428.6 RKO99948.1 - 0.19 12.6 2.6 0.9 10.5 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 RKO99949.1 - 3.3e-34 118.5 0.0 5.6e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) APG9 PF04109.16 RKO99950.1 - 3.3e-172 573.8 2.0 3.8e-172 573.6 2.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Tim17 PF02466.19 RKO99951.1 - 2.2e-14 53.8 2.5 3.8e-14 53.0 2.5 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NPCC PF08058.11 RKO99951.1 - 0.049 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore complex component EFP PF01132.20 RKO99951.1 - 0.14 12.2 0.3 0.27 11.3 0.3 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain WD40 PF00400.32 RKO99952.1 - 3.4e-12 46.7 18.9 0.0027 18.5 0.0 8.2 8 1 0 8 8 8 4 WD domain, G-beta repeat zf-C2H2_jaz PF12171.8 RKO99953.1 - 0.00011 22.4 0.1 0.00018 21.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TRAPP PF04051.16 RKO99954.1 - 6.2e-32 110.3 0.0 7.3e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CAAD PF14159.6 RKO99954.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase AAA PF00004.29 RKO99955.1 - 6.1e-38 130.2 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO99955.1 - 1.9e-07 30.8 1.1 4.1e-07 29.7 0.0 2.1 3 0 0 3 3 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO99955.1 - 9.7e-07 28.9 0.1 5.4e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKO99955.1 - 3.8e-06 26.7 0.0 9.6e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 RKO99955.1 - 1.4e-05 25.0 0.0 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 RKO99955.1 - 2.6e-05 24.5 2.7 0.0034 17.6 0.9 3.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 RKO99955.1 - 0.00013 22.4 4.8 0.036 14.4 0.1 3.1 1 1 2 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 RKO99955.1 - 0.00024 20.4 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 RKO99955.1 - 0.00038 20.6 0.1 0.00073 19.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RKO99955.1 - 0.00063 19.9 0.0 0.0025 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 RKO99955.1 - 0.0019 18.0 0.2 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKO99955.1 - 0.0053 16.2 1.0 0.018 14.4 0.2 2.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 RKO99955.1 - 0.0056 16.1 0.1 11 5.3 0.0 3.1 2 1 0 3 3 3 0 Bacterial TniB protein AAA_25 PF13481.6 RKO99955.1 - 0.017 14.7 3.8 0.11 12.1 0.2 2.9 1 1 2 3 3 3 0 AAA domain TsaE PF02367.17 RKO99955.1 - 0.019 14.9 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RKO99955.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 RKO99955.1 - 0.031 14.0 0.0 3.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_21 PF13304.6 RKO99955.1 - 0.032 14.0 0.3 0.14 12.0 0.0 2.0 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 RKO99955.1 - 0.044 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKO99955.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 RKO99955.1 - 0.07 12.6 0.1 0.23 11.0 0.2 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 RKO99955.1 - 0.086 12.2 0.3 1.9 7.8 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 RKO99955.1 - 0.1 13.1 0.4 0.2 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 RKO99955.1 - 0.12 12.1 0.2 0.3 10.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO99955.1 - 0.27 11.1 0.9 1.9 8.3 0.5 2.2 2 0 0 2 2 2 0 NACHT domain MCM PF00493.23 RKO99956.1 - 9e-95 316.0 0.1 2.1e-94 314.8 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 RKO99956.1 - 1.6e-26 92.6 0.0 3.5e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKO99956.1 - 2.8e-25 88.5 0.6 6.6e-25 87.4 0.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RKO99956.1 - 7.6e-11 42.5 0.0 1.8e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RKO99956.1 - 3.1e-07 30.0 0.0 2.3e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RKO99956.1 - 0.023 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 RKO99956.1 - 0.064 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aft1_HRR PF11787.8 RKO99956.1 - 0.078 14.2 1.7 0.26 12.5 1.7 2.0 1 0 0 1 1 1 0 Aft1 HRR domain Pkinase PF00069.25 RKO99957.1 - 4.4e-32 111.5 0.0 6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO99957.1 - 1.4e-13 50.7 0.0 2.9e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO99957.1 - 0.046 13.0 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like GAS PF13851.6 RKO99958.1 - 0.011 15.1 15.4 0.021 14.2 15.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 RKO99958.1 - 0.013 15.3 10.9 0.014 15.3 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Dad1 PF08649.10 RKO99958.1 - 0.019 15.1 0.9 0.19 11.9 0.5 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad1 CALCOCO1 PF07888.11 RKO99958.1 - 0.022 13.6 15.6 0.026 13.4 15.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CK2S PF15011.6 RKO99958.1 - 0.033 14.1 9.4 0.043 13.7 9.4 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate DHR10 PF18595.1 RKO99958.1 - 0.044 13.8 21.9 0.048 13.7 11.0 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ADIP PF11559.8 RKO99958.1 - 0.058 13.5 19.3 0.076 13.1 19.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 RKO99958.1 - 0.058 12.0 7.4 0.067 11.8 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4618 PF15397.6 RKO99958.1 - 0.067 12.6 12.3 0.65 9.4 5.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-Q PF13094.6 RKO99958.1 - 0.08 13.1 15.7 0.21 11.8 15.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit E2F_CC-MB PF16421.5 RKO99958.1 - 0.084 13.2 8.7 1.8 9.0 0.3 2.1 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Laminin_II PF06009.12 RKO99958.1 - 0.1 12.6 12.1 0.16 12.0 12.1 1.3 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 RKO99958.1 - 0.11 11.4 14.2 0.12 11.2 14.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 RKO99958.1 - 0.11 12.7 11.0 0.15 12.2 11.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 RKO99958.1 - 0.12 12.7 15.3 0.18 12.1 5.0 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain TSC22 PF01166.18 RKO99958.1 - 0.12 12.7 0.4 0.12 12.7 0.4 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF3450 PF11932.8 RKO99958.1 - 0.16 11.3 19.2 0.18 11.1 19.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 RKO99958.1 - 0.2 11.7 21.5 0.3 11.2 21.5 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.9 RKO99958.1 - 0.2 11.0 12.8 0.26 10.6 12.8 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 YabA PF06156.13 RKO99958.1 - 0.21 12.2 9.2 1.5 9.5 3.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 RKO99958.1 - 0.29 11.6 19.7 0.25 11.8 7.7 2.1 1 1 1 2 2 2 0 Cell division protein ZapB DUF2009 PF09418.10 RKO99958.1 - 0.32 10.0 6.5 0.37 9.8 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) PRKG1_interact PF15898.5 RKO99958.1 - 0.37 11.7 13.2 0.57 11.1 12.8 1.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Topoisom_I PF01028.20 RKO99958.1 - 0.49 9.6 8.8 0.58 9.4 8.8 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core DivIC PF04977.15 RKO99958.1 - 0.5 10.2 21.2 0.089 12.6 4.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.9 RKO99958.1 - 0.51 10.3 12.6 0.85 9.5 12.3 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain ATG16 PF08614.11 RKO99958.1 - 0.53 10.5 20.3 1.5 9.0 12.0 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 RKO99958.1 - 0.63 10.1 7.8 1.5 8.9 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) BST2 PF16716.5 RKO99958.1 - 0.63 10.7 17.2 2 9.0 15.9 1.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Fmp27_WPPW PF10359.9 RKO99958.1 - 0.63 8.8 12.8 0.64 8.8 12.8 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 RKO99958.1 - 0.64 10.2 16.8 1.6 9.0 16.8 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.11 RKO99958.1 - 0.66 9.8 13.1 3.9 7.3 1.8 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 APG6_N PF17675.1 RKO99958.1 - 0.73 10.4 17.8 0.63 10.6 13.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region T3SSipB PF16535.5 RKO99958.1 - 0.84 10.1 17.2 1.1 9.7 17.2 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF5094 PF17015.5 RKO99958.1 - 0.97 9.5 5.9 1.1 9.3 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TolA_bind_tri PF16331.5 RKO99958.1 - 1 9.5 18.8 1.7 8.8 11.7 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF4407 PF14362.6 RKO99958.1 - 1.3 8.3 18.1 1.8 7.9 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 RKO99958.1 - 2.2 8.8 12.3 2.7 8.5 5.8 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 RKO99958.1 - 2.3 8.1 8.1 0.38 10.7 2.8 1.9 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Uso1_p115_C PF04871.13 RKO99958.1 - 2.3 8.6 18.6 4.7 7.6 9.1 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 RKO99958.1 - 2.6 8.1 16.4 48 4.0 16.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus THOC7 PF05615.13 RKO99958.1 - 2.8 8.2 17.5 1.9 8.8 6.9 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 TMPIT PF07851.13 RKO99958.1 - 2.9 7.0 9.9 3.6 6.8 9.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Swi5 PF07061.11 RKO99958.1 - 3.6 7.7 13.2 6 7.0 1.0 2.6 1 1 1 2 2 2 0 Swi5 V_ATPase_I PF01496.19 RKO99958.1 - 4.6 5.0 11.3 4.7 5.0 11.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 RKO99958.1 - 4.6 7.8 17.6 7 7.3 8.2 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor OmpH PF03938.14 RKO99958.1 - 5.2 7.4 21.8 8.9 6.7 21.8 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 RKO99958.1 - 6.2 7.3 17.4 2.8e+02 1.9 17.4 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) FtsL PF04999.13 RKO99958.1 - 7.1 6.7 11.3 0.42 10.6 3.8 2.1 1 1 1 2 2 2 0 Cell division protein FtsL TEX13 PF15186.6 RKO99958.1 - 8.6 6.0 15.1 0.54 9.9 9.0 1.8 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family SlyX PF04102.12 RKO99958.1 - 8.9 7.0 19.4 6.9 7.4 8.7 2.2 1 1 1 2 2 2 0 SlyX Peptidase_S46 PF10459.9 RKO99958.1 - 9.7 4.7 13.0 10 4.6 13.0 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF16 PF01519.16 RKO99958.1 - 10 6.7 14.3 1.8 9.1 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5572 PF17733.1 RKO99959.1 - 5.8e-08 32.5 0.4 1.4e-07 31.3 0.4 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) ASH PF15780.5 RKO99959.1 - 4.1e-05 23.7 0.0 0.43 10.8 0.0 6.1 7 0 0 7 7 7 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RKO99959.1 - 0.0067 16.6 1.3 1.7 8.9 0.0 4.6 5 0 0 5 5 5 1 Flagellar-associated PapD-like ATG22 PF11700.8 RKO99960.1 - 2.1e-127 425.7 17.1 2.4e-127 425.5 17.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Tom7 PF08038.12 RKO99960.1 - 0.031 13.9 0.4 0.2 11.4 0.4 2.5 1 0 0 1 1 1 0 TOM7 family TssN PF17555.2 RKO99960.1 - 7.5 5.8 16.7 1.9 7.8 2.9 2.4 3 0 0 3 3 3 0 Type VI secretion system, TssN DUF3301 PF11743.8 RKO99961.1 - 0.026 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF202 PF02656.15 RKO99961.1 - 0.31 11.5 7.7 4.6 7.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) WRNPLPNID PF15017.6 RKO99961.1 - 8.8 7.3 8.0 2.4 9.1 3.5 2.2 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box GDA1_CD39 PF01150.17 RKO99962.1 - 3e-90 302.9 0.0 3.4e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family 4HBT PF03061.22 RKO99963.1 - 2.6e-10 40.5 1.1 4.2e-10 39.8 0.4 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Peripla_BP_6 PF13458.6 RKO99965.1 - 0.0032 17.2 3.5 0.0045 16.7 3.5 1.2 1 0 0 1 1 1 1 Periplasmic binding protein HMG_box PF00505.19 RKO99965.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box Cnd2 PF05786.14 RKO99965.1 - 0.28 9.8 3.7 0.28 9.8 3.7 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 WSD PF15613.6 RKO99966.1 - 6.2e-07 29.8 0.4 9.5e-06 26.0 0.4 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif KELK PF15796.5 RKO99966.1 - 0.15 12.6 0.5 0.4 11.2 0.5 1.7 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Carn_acyltransf PF00755.20 RKO99967.1 - 1.9e-173 578.3 0.0 2.2e-173 578.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SUIM_assoc PF16619.5 RKO99968.1 - 0.00058 19.9 0.8 0.0013 18.7 0.8 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 LRR_8 PF13855.6 RKO99968.1 - 0.044 13.5 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Leucine rich repeat LPMO_10 PF03067.15 RKO99969.1 - 1.4e-06 29.1 0.0 4.4e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ribosomal_L13 PF00572.18 RKO99970.1 - 8.2e-49 165.0 0.0 1e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF668 PF05003.12 RKO99970.1 - 0.11 13.0 0.1 0.49 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Proteasom_PSMB PF10508.9 RKO99971.1 - 3.8e-18 65.3 0.0 1.5e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 Proteasome non-ATPase 26S subunit Bystin PF05291.11 RKO99972.1 - 4.5e-120 400.4 3.9 8.6e-120 399.4 3.9 1.4 1 1 0 1 1 1 1 Bystin Utp14 PF04615.13 RKO99972.1 - 0.44 9.1 8.2 0.62 8.6 8.2 1.1 1 0 0 1 1 1 0 Utp14 protein Pex14_N PF04695.13 RKO99973.1 - 2e-23 83.8 0.2 2e-23 83.8 0.2 2.5 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Allexi_40kDa PF05549.11 RKO99973.1 - 0.0023 17.5 0.1 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 Allexivirus 40kDa protein NPV_P10 PF05531.12 RKO99973.1 - 0.006 17.0 2.0 1.9 9.0 0.3 2.8 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 RKO99973.1 - 0.006 16.6 0.2 0.041 13.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) CCDC154 PF15450.6 RKO99973.1 - 0.0066 15.1 3.5 0.0092 14.6 3.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 ALIX_LYPXL_bnd PF13949.6 RKO99973.1 - 0.025 13.9 1.2 0.071 12.4 1.2 1.7 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV NUDE_C PF04880.13 RKO99973.1 - 0.025 15.0 1.3 0.025 15.0 1.3 2.6 2 1 0 2 2 2 0 NUDE protein, C-terminal conserved region Spc7 PF08317.11 RKO99973.1 - 0.25 10.2 1.7 0.41 9.5 1.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 RKO99973.1 - 0.25 11.6 1.5 12 6.2 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 RKO99973.1 - 0.67 10.6 7.4 0.67 10.6 0.5 2.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SlyX PF04102.12 RKO99973.1 - 8.1 7.1 8.3 88 3.8 5.4 3.4 2 1 2 4 4 4 0 SlyX Sof1 PF04158.14 RKO99974.1 - 5.6e-22 77.8 9.8 1.1e-21 76.9 9.8 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 RKO99974.1 - 2e-18 66.4 8.8 0.0004 21.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO99974.1 - 1.1e-05 25.6 0.3 0.075 13.3 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKO99974.1 - 2.6e-05 24.2 0.1 0.26 11.2 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Axin_b-cat_bind PF08833.10 RKO99974.1 - 0.032 14.3 0.3 0.19 11.9 0.0 2.4 3 0 0 3 3 3 0 Axin beta-catenin binding domain Noc2 PF03715.13 RKO99975.1 - 9.2e-73 245.1 0.3 1.6e-72 244.3 0.3 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 RKO99975.1 - 1.9e-05 23.1 0.1 1.9e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Nop14-like family DUF4515 PF14988.6 RKO99976.1 - 7e-08 32.6 29.0 7e-08 32.6 29.0 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) RhoGEF PF00621.20 RKO99977.1 - 1.3e-42 146.1 0.0 2.2e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain WW PF00397.26 RKO99977.1 - 7.7e-14 51.5 18.6 1.1e-07 31.8 4.0 3.4 2 1 1 3 3 3 2 WW domain PH PF00169.29 RKO99977.1 - 1.5e-05 25.4 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 PH domain CH PF00307.31 RKO99977.1 - 2.9e-05 24.2 0.0 6.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ_SEC7_PH PF16453.5 RKO99977.1 - 0.00025 21.1 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 RKO99977.1 - 0.0061 16.4 0.0 0.12 12.3 0.0 2.3 1 1 0 1 1 1 1 PH domain Glyco_hyd_101C PF17451.2 RKO99977.1 - 0.0069 16.7 0.2 0.021 15.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase 101 beta sandwich domain TYA PF01021.19 RKO99977.1 - 0.04 14.3 0.5 0.04 14.3 0.5 2.6 2 0 0 2 2 2 0 TYA transposon protein CinA PF02464.17 RKO99977.1 - 2.1 7.9 8.6 10 5.7 6.5 2.8 2 0 0 2 2 2 0 Competence-damaged protein LRR_8 PF13855.6 RKO99979.1 - 3.8e-29 100.2 23.9 1.9e-09 37.1 1.3 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RKO99979.1 - 4.1e-19 68.4 11.5 5.3e-07 29.9 0.0 4.1 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKO99979.1 - 0.0013 19.0 12.7 19 6.3 0.1 6.0 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 RKO99979.1 - 0.0063 16.5 19.7 0.55 10.4 0.1 5.8 6 0 0 6 6 6 2 Leucine Rich repeat CREPT PF16566.5 RKO99979.1 - 0.13 12.5 0.4 6.9 6.8 0.0 2.4 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Surfac_D-trimer PF09006.11 RKO99979.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Glutaredoxin PF00462.24 RKO99980.1 - 9.3e-11 41.8 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 RKO99980.1 - 0.034 14.6 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TMEM126 PF07114.11 RKO99980.1 - 0.13 11.6 0.0 2.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 126 Glyoxalase PF00903.25 RKO99981.1 - 1.5e-23 83.4 0.3 4.1e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RKO99981.1 - 3.5e-12 46.6 0.0 8.8e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 RKO99981.1 - 4.1e-07 30.2 0.0 1.2e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 RKO99981.1 - 1.4e-06 28.5 0.2 0.094 12.8 0.0 3.2 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 RKO99981.1 - 0.0054 17.5 0.1 0.36 11.6 0.3 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain Clat_adaptor_s PF01217.20 RKO99982.1 - 4.2e-55 185.6 1.8 4.6e-55 185.5 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIIA PF03153.13 RKO99983.1 - 1e-52 180.6 0.0 1.5e-52 180.0 0.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 RKO99983.1 - 0.23 11.1 0.2 0.34 10.6 0.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 RKO99983.1 - 0.51 8.4 1.6 0.7 7.9 1.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Aldedh PF00171.22 RKO99984.1 - 7.3e-130 433.6 0.0 8.2e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RKO99984.1 - 0.0046 16.1 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) XAP5 PF04921.14 RKO99985.1 - 2.6 7.8 4.0 4.6 7.0 4.0 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator TPR_14 PF13428.6 RKO99986.1 - 1.9e-09 37.5 18.4 0.0055 17.4 0.6 4.5 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RKO99986.1 - 2.6e-08 33.4 10.3 0.11 12.6 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKO99986.1 - 3.9e-07 30.5 14.3 0.0074 16.8 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKO99986.1 - 2.6e-05 24.8 12.3 0.041 14.5 3.8 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKO99986.1 - 0.00014 21.8 4.0 2.3 8.7 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO99986.1 - 0.00076 19.7 15.0 0.073 13.4 1.7 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO99986.1 - 0.0032 18.0 7.0 6.7 7.6 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO99986.1 - 0.016 15.3 13.8 0.025 14.7 3.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RKO99986.1 - 0.084 13.3 0.2 2.2 8.7 0.1 2.5 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TPR_1 PF00515.28 RKO99986.1 - 0.32 10.9 8.4 1.7 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKO99986.1 - 4.9 8.1 16.4 8.1 7.4 1.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKO99986.1 - 6 6.9 10.0 11 6.0 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 RKO99986.1 - 7.8 6.9 11.2 46 4.4 1.1 3.0 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Ion_trans PF00520.31 RKO99988.1 - 0.069 12.4 0.2 0.11 11.6 0.2 1.4 1 1 0 1 1 1 0 Ion transport protein Metallophos PF00149.28 RKO99989.1 - 1.7e-11 45.0 2.9 2.9e-11 44.2 2.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 RKO99990.1 - 1.9e-14 52.0 8.3 4.6e-06 25.8 0.6 4.4 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 RKO99990.1 - 1.1e-13 51.4 9.3 5.6e-08 33.1 1.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RKO99990.1 - 9.9e-12 43.8 9.7 0.00099 18.9 0.3 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 RKO99990.1 - 2.5e-11 42.6 2.9 0.00014 21.2 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RKO99990.1 - 8.3e-08 32.0 12.0 0.00036 20.3 1.2 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 RKO99990.1 - 0.046 13.7 1.0 0.082 12.9 0.1 1.8 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 RKO99990.1 - 0.27 11.5 3.3 1 9.6 2.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain DUF2722 PF10846.8 RKO99991.1 - 0.00036 19.6 22.1 0.00041 19.4 22.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Suf PF05843.14 RKO99991.1 - 0.0018 18.3 9.7 0.0018 18.3 9.7 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Med15 PF09606.10 RKO99991.1 - 0.0025 16.6 19.9 0.0025 16.6 19.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 RKO99991.1 - 0.0037 17.3 22.8 0.0037 17.3 22.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FAD_binding_9 PF08021.11 RKO99991.1 - 0.0054 16.9 1.4 0.0071 16.6 1.4 1.1 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF702 PF05142.12 RKO99991.1 - 0.011 16.2 7.0 0.011 16.2 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SpoIIP PF07454.11 RKO99991.1 - 0.012 15.0 5.9 0.012 15.1 5.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 RKO99991.1 - 0.015 16.0 13.4 0.015 16.0 13.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4770 PF15994.5 RKO99991.1 - 0.032 14.5 7.8 0.033 14.4 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Band_3_cyto PF07565.13 RKO99991.1 - 0.039 13.8 3.9 0.037 13.8 3.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ORC_WH_C PF18137.1 RKO99991.1 - 0.042 13.9 6.5 0.048 13.7 6.5 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RPA43_OB PF17875.1 RKO99991.1 - 0.046 14.4 4.0 0.049 14.3 4.0 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Presenilin PF01080.17 RKO99991.1 - 0.065 12.0 9.0 0.068 11.9 9.0 1.0 1 0 0 1 1 1 0 Presenilin PPL5 PF18168.1 RKO99991.1 - 0.067 12.5 2.2 0.072 12.4 2.2 1.0 1 0 0 1 1 1 0 Prim-pol family 5 PAT1 PF09770.9 RKO99991.1 - 0.068 11.4 13.3 0.068 11.4 13.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Androgen_recep PF02166.16 RKO99991.1 - 0.07 12.0 25.0 0.087 11.7 25.0 1.3 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 RKO99991.1 - 0.078 14.0 13.0 0.11 13.5 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EPL1 PF10513.9 RKO99991.1 - 0.09 13.2 8.2 0.096 13.1 8.2 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2368 PF10166.9 RKO99991.1 - 0.097 12.3 7.6 0.097 12.3 7.6 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DDHD PF02862.17 RKO99991.1 - 0.13 12.5 6.2 0.12 12.5 6.2 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.12 RKO99991.1 - 0.13 11.3 16.0 0.13 11.2 16.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 RKO99991.1 - 0.14 12.4 5.2 0.15 12.2 5.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFB6 PF17110.5 RKO99991.1 - 0.14 11.9 5.0 0.16 11.7 5.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH XRN_M PF17846.1 RKO99991.1 - 0.15 11.0 4.0 0.17 10.8 4.0 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Spt20 PF12090.8 RKO99991.1 - 0.19 11.3 35.9 0.24 11.0 35.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF1800 PF08811.11 RKO99991.1 - 0.22 10.5 10.2 0.22 10.5 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) MecA PF05389.12 RKO99991.1 - 0.22 11.1 5.9 0.24 11.0 5.9 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) TERB2 PF15101.6 RKO99991.1 - 0.22 11.5 13.4 0.25 11.4 13.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MDM10 PF12519.8 RKO99991.1 - 0.24 10.2 4.1 0.23 10.3 4.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RskA PF10099.9 RKO99991.1 - 0.24 11.7 8.3 0.3 11.4 8.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA YABBY PF04690.13 RKO99991.1 - 0.28 11.7 4.8 0.33 11.5 4.8 1.1 1 0 0 1 1 1 0 YABBY protein DUF3408 PF11888.8 RKO99991.1 - 0.31 11.2 10.0 0.36 10.9 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Connexin PF00029.19 RKO99991.1 - 0.38 10.5 7.3 0.44 10.3 7.3 1.1 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 RKO99991.1 - 0.39 10.7 5.4 0.39 10.7 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.6 RKO99991.1 - 0.39 10.4 5.2 0.46 10.1 5.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF775 PF05603.12 RKO99991.1 - 0.42 10.1 9.8 0.48 9.9 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PepSY_TM PF03929.16 RKO99991.1 - 0.42 10.2 6.9 0.47 10.1 6.9 1.0 1 0 0 1 1 1 0 PepSY-associated TM region DUF4518 PF15008.6 RKO99991.1 - 0.45 9.6 8.7 0.5 9.5 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RR_TM4-6 PF06459.12 RKO99991.1 - 0.53 10.1 8.8 0.61 9.9 8.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 RKO99991.1 - 0.55 9.6 16.8 0.64 9.4 16.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ctr PF04145.15 RKO99991.1 - 0.62 10.7 4.7 0.7 10.5 4.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF2126 PF09899.9 RKO99991.1 - 0.65 8.0 6.8 0.74 7.8 6.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3405 PF11885.8 RKO99991.1 - 0.73 8.4 9.8 0.83 8.2 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Ndc1_Nup PF09531.10 RKO99991.1 - 0.73 8.4 5.9 0.69 8.5 5.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIF_C PF14721.6 RKO99991.1 - 0.83 10.0 7.2 1 9.7 7.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Paf1 PF03985.13 RKO99991.1 - 0.88 8.5 12.8 1 8.3 12.8 1.0 1 0 0 1 1 1 0 Paf1 EIIBC-GUT_N PF03612.14 RKO99991.1 - 0.89 9.3 9.3 1.1 9.0 9.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.19 RKO99991.1 - 0.9 7.4 9.0 0.96 7.3 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 RKO99991.1 - 0.96 8.1 4.8 1 8.0 4.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier FHIPEP PF00771.20 RKO99991.1 - 1.1 7.7 5.5 1 7.7 5.5 1.0 1 0 0 1 1 1 0 FHIPEP family DUF1980 PF09323.10 RKO99991.1 - 1.2 9.1 5.4 1.2 9.0 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Sec62 PF03839.16 RKO99991.1 - 1.3 8.5 5.7 1.5 8.3 5.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CLN3 PF02487.17 RKO99991.1 - 1.3 7.9 5.9 1.5 7.8 5.9 1.0 1 0 0 1 1 1 0 CLN3 protein Plasmodium_Vir PF05795.11 RKO99991.1 - 1.4 8.3 3.8 1.3 8.3 3.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2828 PF11443.8 RKO99991.1 - 1.4 6.9 10.3 1.5 6.8 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) G0-G1_switch_2 PF15103.6 RKO99991.1 - 1.5 9.3 9.3 1.9 9.0 9.3 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 OATP PF03137.20 RKO99991.1 - 1.5 7.0 4.8 1.4 7.1 4.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CSG2 PF16965.5 RKO99991.1 - 1.9 7.3 4.1 2.1 7.2 4.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4407 PF14362.6 RKO99991.1 - 1.9 7.7 13.3 2.1 7.6 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 RKO99991.1 - 2 7.1 5.7 2.2 7.0 5.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0560 PF10577.9 RKO99991.1 - 2.1 6.7 16.0 2.3 6.6 16.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.6 RKO99991.1 - 2.2 6.1 27.5 2.4 6.0 27.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EOS1 PF12326.8 RKO99991.1 - 2.3 8.1 6.1 2.5 8.0 6.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein Rrn6 PF10214.9 RKO99991.1 - 2.3 6.6 13.7 2.4 6.5 13.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3464 PF11947.8 RKO99991.1 - 2.3 7.9 12.3 2.9 7.6 12.3 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CDC45 PF02724.14 RKO99991.1 - 2.8 6.1 10.1 3 6.0 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein PIP5K PF01504.18 RKO99991.1 - 2.8 7.1 9.5 3.3 6.9 9.5 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Kei1 PF08552.11 RKO99991.1 - 3.1 7.7 6.3 3.5 7.5 6.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NARP1 PF12569.8 RKO99991.1 - 3.9 6.3 12.4 4.5 6.1 12.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Baculo_PP31 PF05311.11 RKO99991.1 - 4.1 6.8 10.2 4.6 6.6 10.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3043 PF11241.8 RKO99991.1 - 4.3 7.3 11.5 5 7.1 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Coilin_N PF15862.5 RKO99991.1 - 4.8 7.0 15.3 6.5 6.6 15.3 1.1 1 0 0 1 1 1 0 Coilin N-terminus Ureide_permease PF07168.11 RKO99991.1 - 5.2 5.7 4.5 6.3 5.5 4.5 1.1 1 0 0 1 1 1 0 Ureide permease Hid1 PF12722.7 RKO99991.1 - 6 4.9 9.8 6.4 4.8 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 RKO99991.1 - 6.5 5.9 4.7 7.1 5.7 4.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM51 PF15345.6 RKO99991.1 - 6.6 6.5 20.5 8.5 6.1 20.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 PhoLip_ATPase_C PF16212.5 RKO99992.1 - 2.3e-47 161.8 21.0 2.3e-47 161.8 21.0 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKO99992.1 - 4.8e-17 61.4 3.3 1.3e-16 60.0 3.3 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RKO99992.1 - 2.6e-13 50.7 0.2 3.1e-08 34.2 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RKO99992.1 - 8.6e-11 41.7 0.0 8.6e-11 41.7 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 RKO99992.1 - 1.1e-09 38.3 0.0 1.4e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKO99992.1 - 0.0009 19.1 0.0 0.0042 16.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NUFIP1 PF10453.9 RKO99994.1 - 3.9e-12 45.8 0.5 3.9e-12 45.8 0.5 1.5 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) End3 PF12761.7 RKO99994.1 - 0.079 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 YihI PF04220.12 RKO99994.1 - 2.5 7.8 4.1 6.3 6.5 4.1 1.6 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF2183 PF09949.9 RKO99995.1 - 6e-23 81.1 0.0 1.6e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) SSXT PF05030.12 RKO99997.1 - 2.1e-08 33.7 0.1 2.1e-08 33.7 0.1 2.6 3 0 0 3 3 3 1 SSXT protein (N-terminal region) DDHD PF02862.17 RKO99997.1 - 0.064 13.4 11.3 0.043 14.0 4.6 2.2 2 0 0 2 2 2 0 DDHD domain Tmp39 PF10271.9 RKO99997.1 - 0.15 11.0 1.9 0.22 10.5 1.9 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Peroxin-13_N PF04088.13 RKO99997.1 - 1.2 9.4 8.0 3.1 8.1 8.0 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region eIF-3_zeta PF05091.12 RKO99997.1 - 1.9 7.3 20.0 3.3 6.6 20.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EPL1 PF10513.9 RKO99997.1 - 2.9 8.3 11.6 0.26 11.7 5.2 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like PA26 PF04636.13 RKO99997.1 - 7.3 5.4 12.7 11 4.8 12.7 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FapA PF03961.13 RKO99997.1 - 9.6 4.7 8.4 13 4.2 8.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SH3_1 PF00018.28 RKO99998.1 - 0.0005 19.6 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKO99998.1 - 0.0017 18.1 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LPG_synthase_TM PF03706.13 RKO99998.1 - 0.047 13.2 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Mid2 PF04478.12 RKO99998.1 - 0.078 12.8 0.0 0.078 12.8 0.0 2.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2062 PF09835.9 RKO99998.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) TMEM154 PF15102.6 RKO99998.1 - 1.6 8.6 0.0 1.6 8.6 0.0 3.9 4 2 0 4 4 4 0 TMEM154 protein family Glyco_transf_17 PF04724.13 RKO99999.1 - 3.7e-146 486.7 0.0 4.5e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 PDH PF02153.17 RKP00003.1 - 2.9e-15 56.0 0.0 4.9e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 RKP00003.1 - 1.9e-06 28.1 0.0 3.3e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RKP00003.1 - 3.5e-05 24.3 0.1 0.0001 22.8 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 RKP00003.1 - 0.0049 16.9 0.0 0.022 14.9 0.0 2.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 RKP00005.1 - 6.1e-43 146.4 0.0 1.8e-42 144.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP00005.1 - 4.4e-06 27.2 6.5 0.0019 18.6 0.0 3.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_lid_3 PF17862.1 RKP00005.1 - 5.9e-05 22.8 0.7 0.00013 21.7 0.7 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 RKP00005.1 - 0.00014 21.7 0.0 0.00049 19.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKP00005.1 - 0.00014 22.1 0.2 0.013 15.7 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 RKP00005.1 - 0.00018 21.5 0.1 0.0013 18.8 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RKP00005.1 - 0.00047 20.3 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 RKP00005.1 - 0.00088 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 KaiC Parvo_NS1 PF01057.17 RKP00005.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 RKP00005.1 - 0.0039 16.6 0.1 0.013 14.9 0.1 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 RKP00005.1 - 0.0044 16.6 0.0 0.0081 15.7 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 RKP00005.1 - 0.0063 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 RKP00005.1 - 0.011 15.3 2.6 0.13 11.8 0.1 2.6 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 RKP00005.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 RKP00005.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 RKP00005.1 - 0.03 13.5 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 RKP00005.1 - 0.035 13.8 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RKP00005.1 - 0.036 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 RKP00005.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 RKP00005.1 - 0.052 14.1 0.0 0.09 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RKP00005.1 - 0.067 12.9 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 RKP00005.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 RKP00005.1 - 0.088 13.0 0.4 0.21 11.7 0.0 2.0 3 1 0 3 3 1 0 AAA domain AAA_28 PF13521.6 RKP00005.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKP00005.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 RKP00005.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 RKP00005.1 - 0.12 11.5 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.6 RKP00005.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 RKP00005.1 - 0.2 11.7 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 RKP00006.1 - 1.1e-42 145.8 0.0 3.7e-27 95.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RKP00006.1 - 2.5e-40 138.9 20.8 2e-22 80.1 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 RKP00006.1 - 5.4e-06 26.4 0.0 0.3 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 RKP00006.1 - 2.3e-05 24.4 0.3 0.01 15.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKP00006.1 - 7.4e-05 22.7 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 RKP00006.1 - 0.00031 20.8 1.2 0.41 10.7 0.1 2.4 2 0 0 2 2 2 2 Dynamin family SMC_N PF02463.19 RKP00006.1 - 0.00035 20.1 0.1 2.4 7.6 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RKP00006.1 - 0.02 15.4 0.1 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RKP00006.1 - 0.029 14.6 0.3 4 7.7 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 RKP00006.1 - 0.031 14.5 0.0 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKP00006.1 - 0.055 13.0 0.3 1.1 8.7 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region cobW PF02492.19 RKP00006.1 - 0.064 12.8 0.7 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 RKP00006.1 - 0.082 12.7 0.6 0.45 10.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 RKP00006.1 - 0.17 11.2 0.3 8 5.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 RKP00006.1 - 0.36 11.2 7.9 0.11 12.9 0.4 3.2 2 2 0 2 2 2 0 AAA ATPase domain CUE PF02845.16 RKP00007.1 - 3e-07 30.0 0.0 6.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 CUE domain TALPID3 PF15324.6 RKP00007.1 - 0.61 7.7 3.0 0.91 7.1 3.0 1.2 1 0 0 1 1 1 0 Hedgehog signalling target TFIID-18kDa PF02269.16 RKP00008.1 - 3.2e-14 52.7 0.0 3.5e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PX PF00787.24 RKP00009.1 - 1.5e-22 79.7 0.0 1.7e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 PX domain Glyco_hydr_30_2 PF14587.6 RKP00010.1 - 2.1e-26 93.4 0.3 3.9e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 RKP00010.1 - 0.00033 20.0 0.0 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 RKP00010.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain DUF1664 PF07889.12 RKP00011.1 - 0.0017 18.4 22.7 0.036 14.1 0.4 4.8 3 2 3 6 6 6 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 RKP00011.1 - 0.015 14.2 39.3 0.15 11.0 1.5 4.2 3 1 1 4 4 4 0 Spc7 kinetochore protein GPS2_interact PF15784.5 RKP00011.1 - 0.068 13.6 0.1 0.068 13.6 0.1 4.0 4 1 0 4 4 4 0 G-protein pathway suppressor 2-interacting domain Filament PF00038.21 RKP00011.1 - 0.069 12.7 43.6 2.5 7.6 2.6 3.4 2 1 1 3 3 3 0 Intermediate filament protein Curto_V2 PF07325.11 RKP00011.1 - 0.078 12.9 0.6 0.14 12.0 0.6 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein ABC_tran_CTD PF16326.5 RKP00011.1 - 0.3 11.4 39.9 0.29 11.4 5.2 6.4 5 3 1 6 6 6 0 ABC transporter C-terminal domain DUF1192 PF06698.11 RKP00011.1 - 2.3 8.4 13.9 1.3 9.2 0.1 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) Gluconate_2-dh3 PF13618.6 RKP00011.1 - 4.6 7.5 20.5 32 4.7 16.0 3.4 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Hist_deacetyl PF00850.19 RKP00011.1 - 6.8 6.1 8.0 8 5.8 6.5 1.7 1 1 0 1 1 1 0 Histone deacetylase domain DUF1140 PF06600.11 RKP00011.1 - 9.1 6.8 10.3 2.6 8.6 3.7 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1140) FOXP-CC PF16159.5 RKP00012.1 - 0.0098 16.5 0.4 0.0098 16.5 0.4 3.7 2 1 2 4 4 4 1 FOXP coiled-coil domain ZapB PF06005.12 RKP00012.1 - 0.31 11.5 2.6 0.59 10.6 2.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF2353 PF09789.9 RKP00012.1 - 0.43 9.9 1.4 0.63 9.3 1.4 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HALZ PF02183.18 RKP00012.1 - 0.68 10.2 3.1 0.22 11.8 0.3 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-C2H2 PF00096.26 RKP00012.1 - 2.5 8.7 15.2 2.5 8.7 3.5 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP00012.1 - 3.2 8.8 14.2 0.61 11.1 2.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger OSCP PF00213.18 RKP00013.1 - 5e-47 160.2 1.1 6.8e-47 159.8 1.1 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit POT1PC PF16686.5 RKP00014.1 - 7.3e-05 22.7 0.0 0.0027 17.6 0.0 2.3 1 1 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 RKP00014.1 - 9.8e-05 22.2 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 MamL-1 PF09596.10 RKP00014.1 - 0.17 12.1 1.5 0.37 11.1 1.5 1.6 1 0 0 1 1 1 0 MamL-1 domain FSA_C PF10479.9 RKP00014.1 - 6.1 4.9 5.8 8.4 4.4 5.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ALG11_N PF15924.5 RKP00015.1 - 7.2e-73 245.1 0.1 1.1e-72 244.5 0.1 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 RKP00015.1 - 5.3e-17 61.9 0.0 7.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RKP00015.1 - 3.2e-13 50.3 0.4 7.4e-13 49.1 0.4 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RKP00015.1 - 0.0052 17.1 2.8 0.0084 16.5 0.0 2.6 2 1 1 3 3 3 1 Glycosyl transferases group 1 Mito_carr PF00153.27 RKP00016.1 - 1.4e-52 175.6 1.0 1.6e-21 76.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cerato-platanin PF07249.12 RKP00017.1 - 0.0038 17.3 0.1 0.0083 16.2 0.1 1.6 1 0 0 1 1 1 1 Cerato-platanin SIL1 PF16782.5 RKP00019.1 - 0.0032 16.7 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 RKP00019.1 - 0.0098 16.3 0.1 7.7 7.0 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats PUL PF08324.11 RKP00019.1 - 0.087 12.0 0.0 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 PUL domain PET117 PF15786.5 RKP00020.1 - 0.099 12.9 18.0 9.7 6.5 18.0 2.0 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial RapH_N PF18801.1 RKP00020.1 - 0.15 12.1 1.1 1.2 9.3 0.5 2.0 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal PCI PF01399.27 RKP00022.1 - 6.8e-14 52.3 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF4810 PF16068.5 RKP00022.1 - 0.11 13.0 0.0 0.59 10.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TSC22 PF01166.18 RKP00023.1 - 0.27 11.6 8.3 15 6.0 0.1 4.5 4 0 0 4 4 4 0 TSC-22/dip/bun family TMPIT PF07851.13 RKP00023.1 - 0.3 10.3 11.3 3.8 6.7 0.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 RKP00023.1 - 0.37 10.8 18.7 1.5 8.8 6.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 RKP00023.1 - 0.46 9.3 36.9 0.29 10.0 17.2 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF948 PF06103.11 RKP00023.1 - 0.9 9.8 11.6 0.75 10.1 0.8 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 RKP00023.1 - 1.6 8.9 56.5 2.7 8.2 30.4 5.0 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 RKP00023.1 - 1.7 8.7 33.7 0.022 14.7 2.1 5.3 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 RKP00023.1 - 1.9 7.0 12.9 0.1 11.2 3.9 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Filament PF00038.21 RKP00023.1 - 1.9 8.0 35.1 6.7 6.2 0.1 3.7 2 1 2 4 4 4 0 Intermediate filament protein AAA_13 PF13166.6 RKP00023.1 - 2.4 6.7 19.5 7.5 5.1 0.4 2.2 1 1 0 2 2 2 0 AAA domain KASH_CCD PF14662.6 RKP00023.1 - 2.6 7.8 36.0 0.69 9.7 20.6 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 RKP00023.1 - 2.8 8.3 19.2 2.1 8.7 2.2 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 RKP00023.1 - 3 8.0 34.9 0.047 13.9 1.7 3.6 3 1 0 3 3 3 0 Tropomyosin like MAD PF05557.13 RKP00023.1 - 6 5.1 33.4 0.27 9.6 26.0 2.1 2 1 0 2 2 2 0 Mitotic checkpoint protein FliD_C PF07195.12 RKP00023.1 - 6.4 6.1 11.1 5.3 6.4 2.7 2.8 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus HMMR_N PF15905.5 RKP00023.1 - 6.5 6.1 30.2 0.66 9.4 23.0 2.5 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF3818 PF12825.7 RKP00023.1 - 7.9 5.4 8.0 13 4.7 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) YabA PF06156.13 RKP00023.1 - 8.8 7.0 20.0 6.2 7.5 0.4 3.9 3 1 1 4 4 4 0 Initiation control protein YabA ERM PF00769.19 RKP00023.1 - 8.9 6.1 40.2 1.2e+02 2.3 12.9 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Nsp1_C PF05064.13 RKP00023.1 - 9.2 6.1 24.7 6.1 6.7 7.2 4.0 2 1 2 4 4 4 0 Nsp1-like C-terminal region GIT_CC PF16559.5 RKP00023.1 - 9.4 6.2 17.5 0.091 12.6 0.5 4.0 4 1 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Zn_clus PF00172.18 RKP00024.1 - 0.0017 18.4 8.4 0.0024 17.9 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cNMP_binding PF00027.29 RKP00025.1 - 9.6e-17 60.8 0.0 2.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-C3HC4_3 PF13920.6 RKP00026.1 - 0.01 15.7 8.4 0.022 14.6 8.4 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP00026.1 - 0.28 11.1 8.8 0.48 10.3 8.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DCX PF03607.17 RKP00027.1 - 7.5e-28 96.4 0.0 1.3e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Doublecortin WD40 PF00400.32 RKP00028.1 - 8.4e-42 140.4 23.0 2e-08 34.7 0.4 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00028.1 - 4.1e-24 84.7 2.7 5.9e-06 26.5 0.2 6.1 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKP00028.1 - 3.3e-11 43.4 0.3 0.002 18.0 0.1 3.1 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RKP00028.1 - 3.7e-06 26.1 0.5 0.045 12.7 0.1 3.7 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 RKP00028.1 - 0.016 15.1 0.2 1.7 8.7 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 RKP00028.1 - 0.016 13.9 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like IKI3 PF04762.12 RKP00028.1 - 0.15 10.0 0.0 1.9 6.4 0.0 2.3 1 1 1 3 3 3 0 IKI3 family E1-E2_ATPase PF00122.20 RKP00030.1 - 5.6e-40 136.8 0.2 5.6e-40 136.8 0.2 2.5 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RKP00030.1 - 1.5e-38 133.2 2.7 3.6e-38 132.0 2.7 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 RKP00030.1 - 8.7e-37 125.4 0.2 2e-12 47.3 0.0 3.7 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 RKP00030.1 - 0.0039 17.0 1.2 0.0082 15.9 0.9 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 RKP00030.1 - 0.29 11.5 4.8 21 5.6 0.1 3.8 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain FeS_assembly_P PF01883.19 RKP00030.1 - 0.34 11.1 1.8 47 4.3 0.0 3.7 4 0 0 4 4 4 0 Iron-sulfur cluster assembly protein Cyt-b5 PF00173.28 RKP00031.1 - 5.9e-25 87.2 0.1 6.6e-25 87.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4079 PF13301.6 RKP00032.1 - 0.0078 16.4 2.9 0.0078 16.4 2.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 RKP00032.1 - 0.0097 16.1 7.1 0.0097 16.1 7.1 2.3 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 KH_6 PF15985.5 RKP00033.1 - 9e-12 45.2 0.2 1.8e-11 44.2 0.2 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 RKP00033.1 - 1.4e-11 43.9 0.3 3.1e-11 42.9 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 RKP00033.1 - 0.017 15.7 0.4 3.7 8.2 0.1 2.5 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 Calici_MSP PF05752.11 RKP00034.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein MtrC PF04211.13 RKP00034.1 - 0.095 11.7 2.8 0.15 11.1 2.8 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C PQQ_3 PF13570.6 RKP00035.1 - 0.0048 17.4 1.9 0.13 12.8 0.0 4.0 2 0 0 2 2 2 1 PQQ-like domain WD40 PF00400.32 RKP00035.1 - 0.048 14.5 0.0 0.91 10.5 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_S24 PF00717.23 RKP00036.1 - 1.2e-12 47.6 0.0 2.3e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 RKP00036.1 - 1.3e-07 31.5 0.0 6.1e-05 22.8 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Tic110 PF16940.5 RKP00038.1 - 8 4.8 11.7 8.3 4.8 11.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter PIP5K PF01504.18 RKP00039.1 - 9.2e-96 320.3 0.0 1.3e-95 319.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ApbA_C PF08546.11 RKP00040.1 - 2.2e-21 76.4 0.0 3.5e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 RKP00040.1 - 7.1e-13 48.5 0.0 1.6e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AAA_6 PF12774.7 RKP00041.1 - 7.4e-85 284.8 0.0 5.9e-81 272.0 0.0 3.9 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKP00041.1 - 1.3e-61 208.9 0.5 1e-60 206.0 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RKP00041.1 - 1.2e-41 142.3 0.0 2.9e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_5 PF07728.14 RKP00041.1 - 1.4e-23 83.5 0.0 8.9e-14 51.7 0.0 4.2 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) MT PF12777.7 RKP00041.1 - 1.5e-20 73.5 5.5 1.5e-20 73.5 5.5 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RKP00041.1 - 2e-18 66.7 0.0 4.2e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKP00041.1 - 3.3e-13 49.8 0.1 2.5e-11 43.7 0.0 3.7 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 RKP00041.1 - 7.7e-10 38.5 0.1 5.9e-09 35.6 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain DHC_N1 PF08385.12 RKP00041.1 - 1.1e-08 34.3 0.0 1.7e-07 30.3 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 RKP00041.1 - 2.7e-05 23.7 0.0 0.026 14.1 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_22 PF13401.6 RKP00041.1 - 0.00023 21.5 0.0 0.78 10.0 0.0 4.1 3 0 0 3 3 2 1 AAA domain DUF4686 PF15742.5 RKP00041.1 - 0.0022 17.2 0.8 0.0022 17.2 0.8 3.7 4 0 0 4 4 3 1 Domain of unknown function (DUF4686) AAA PF00004.29 RKP00041.1 - 0.0071 16.8 0.0 0.21 12.0 0.0 3.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RKP00041.1 - 0.028 14.6 0.7 14 5.9 0.0 4.7 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 RKP00041.1 - 0.052 13.3 0.3 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RKP00041.1 - 0.21 12.0 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 RKP00041.1 - 0.48 10.8 0.0 0.48 10.8 0.0 9.2 10 1 0 10 10 10 0 AAA ATPase domain Gtr1_RagA PF04670.12 RKP00042.1 - 1.1e-100 335.8 0.0 1.3e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 RKP00042.1 - 1.8e-09 37.8 0.0 4.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RKP00042.1 - 2.7e-08 33.6 0.0 6.4e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.21 RKP00042.1 - 2.6e-07 30.3 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKP00042.1 - 4.8e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKP00042.1 - 0.0096 15.5 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 RKP00042.1 - 0.05 14.1 0.0 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 RKP00042.1 - 0.052 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RKP00042.1 - 0.068 12.3 4.3 0.83 8.7 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.9 RKP00042.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RKP00042.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RKP00042.1 - 0.15 12.0 0.1 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Pam16 PF03656.13 RKP00044.1 - 6.3e-21 74.7 1.5 9.2e-21 74.2 1.5 1.2 1 0 0 1 1 1 1 Pam16 Sec6 PF06046.13 RKP00044.1 - 0.09 11.1 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 Ribosomal_60s PF00428.19 RKP00044.1 - 4.9 7.8 12.7 10 6.8 4.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein UQ_con PF00179.26 RKP00045.1 - 1.3e-50 170.7 0.0 1.4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKP00045.1 - 0.0049 17.1 0.0 0.0097 16.2 0.0 1.6 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.6 RKP00045.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 RKP00045.1 - 0.047 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF2420 PF10336.9 RKP00046.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) RPA43_OB PF17875.1 RKP00048.1 - 2.2e-10 41.2 0.0 2.2e-10 41.2 0.0 4.5 2 2 1 3 3 3 1 RPA43 OB domain in RNA Pol I Citrate_bind PF16114.5 RKP00049.1 - 1.7e-85 285.0 0.0 3.2e-85 284.1 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 RKP00049.1 - 1e-19 70.9 0.2 4.8e-18 65.4 0.1 2.6 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 RKP00049.1 - 1.1e-12 48.4 0.0 3e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 RKP00049.1 - 1.4e-11 44.4 0.1 4.3e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_2 PF08442.10 RKP00049.1 - 8.1e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 RKP00049.1 - 9.6e-06 25.4 0.0 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Reovirus_M2 PF05993.12 RKP00049.1 - 0.019 13.1 0.1 0.11 10.6 0.0 1.9 2 0 0 2 2 2 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Pro_isomerase PF00160.21 RKP00050.1 - 8.1e-46 156.2 0.3 1e-45 155.9 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Glyco_transf_8 PF01501.20 RKP00052.1 - 9.4e-22 77.8 0.0 5e-21 75.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RKP00052.1 - 0.015 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative DUF948 PF06103.11 RKP00053.1 - 0.041 14.1 0.4 0.2 11.9 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SNARE PF05739.19 RKP00053.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 SNARE domain tRNA-synt_1b PF00579.25 RKP00054.1 - 1.6e-65 221.4 0.0 1.9e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 RKP00054.1 - 4.7e-20 71.5 0.1 9.8e-20 70.5 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain COG7 PF10191.9 RKP00055.1 - 9.9e-13 47.2 4.1 1.1e-11 43.7 0.1 3.0 3 0 0 3 3 3 2 Golgi complex component 7 (COG7) DUF2457 PF10446.9 RKP00055.1 - 6.4 5.8 15.3 0.49 9.5 8.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Sec10 PF07393.11 RKP00056.1 - 2.6e-146 489.0 0.1 6.2e-146 487.7 0.1 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec10 MscS_porin PF12795.7 RKP00056.1 - 0.052 13.1 1.2 0.18 11.3 1.2 1.9 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain IFT57 PF10498.9 RKP00056.1 - 0.091 11.7 0.7 1.4 7.8 0.2 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 LRR_6 PF13516.6 RKP00057.1 - 1.4e-07 31.0 2.9 1.6 9.0 0.2 4.6 4 0 0 4 4 4 4 Leucine Rich repeat LRR_8 PF13855.6 RKP00057.1 - 0.0058 16.4 0.4 0.077 12.8 0.1 2.6 2 1 0 2 2 2 1 Leucine rich repeat Apo-CIII PF05778.12 RKP00058.1 - 0.48 10.1 4.0 0.92 9.2 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF1664 PF07889.12 RKP00058.1 - 0.5 10.4 12.2 0.81 9.7 0.8 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 RKP00058.1 - 1.6 9.0 21.7 0.35 11.1 0.6 5.0 5 2 1 6 6 6 0 JNK-interacting protein leucine zipper II Prominin PF05478.11 RKP00058.1 - 1.7 6.5 10.3 0.87 7.5 7.8 1.6 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 RKP00058.1 - 3.2 7.8 7.1 3.9 7.5 0.3 3.2 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 RKP00058.1 - 3.4 8.0 20.2 20 5.5 13.7 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 RKP00058.1 - 7.3 6.4 12.0 2.9 7.6 1.6 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF573 PF04504.14 RKP00058.1 - 8.2 7.2 12.2 0.94 10.2 0.9 3.6 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Sec66 PF09802.9 RKP00059.1 - 6.4e-27 94.3 0.0 7e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4681 PF15732.5 RKP00059.1 - 0.15 12.3 0.3 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) Med17 PF10156.9 RKP00060.1 - 2.1e-07 30.0 0.0 2.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Subunit 17 of Mediator complex Mito_fiss_reg PF05308.11 RKP00060.1 - 1.1 9.2 12.3 1 9.4 4.2 2.7 2 0 0 2 2 2 0 Mitochondrial fission regulator DNA_pol_E_B PF04042.16 RKP00061.1 - 1.4e-40 138.9 1.1 2e-40 138.4 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B VWA_2 PF13519.6 RKP00062.1 - 0.0037 17.9 0.1 0.019 15.6 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain PatG_D PF18047.1 RKP00062.1 - 0.06 13.8 0.0 0.28 11.6 0.0 2.0 2 1 1 3 3 3 0 PatG Domain VWA PF00092.28 RKP00062.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Pex14_N PF04695.13 RKP00063.1 - 0.061 14.0 6.1 0.12 13.0 6.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.11 RKP00063.1 - 0.93 9.9 20.0 3 8.3 20.0 1.9 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GKAP PF03359.13 RKP00063.1 - 1.3 8.5 3.7 2 7.9 3.7 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein FSA_C PF10479.9 RKP00063.1 - 4 5.5 17.4 6.7 4.7 17.4 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CRAL_TRIO PF00650.20 RKP00064.1 - 8.8e-37 126.3 0.0 1.2e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RKP00064.1 - 2.6e-06 27.5 0.7 5.6e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF5448 PF17526.2 RKP00064.1 - 0.2 11.9 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5448) DDHD PF02862.17 RKP00065.1 - 1.2e-42 146.6 0.0 2.4e-42 145.6 0.0 1.5 1 0 0 1 1 1 1 DDHD domain Pkinase PF00069.25 RKP00066.1 - 4.5e-74 249.1 0.0 5.2e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00066.1 - 3.1e-45 154.5 0.0 3.8e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00066.1 - 1.1e-06 28.2 0.0 2.2e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RKP00066.1 - 0.00012 21.7 0.4 0.00017 21.3 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RKP00066.1 - 0.0035 16.7 0.7 0.0059 16.0 0.7 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP00066.1 - 0.0065 15.5 0.1 0.0085 15.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKP00066.1 - 0.051 13.5 0.2 0.21 11.5 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family KA1 PF02149.19 RKP00067.1 - 1.4e-18 66.4 0.1 1.8e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Kinase associated domain 1 Lentiviral_Tat PF02998.14 RKP00067.1 - 0.087 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Lentiviral Tat protein LRR_9 PF14580.6 RKP00068.1 - 3.6e-12 46.1 0.1 0.013 15.1 0.0 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 RKP00068.1 - 7.6e-11 42.1 3.8 0.0014 19.0 0.6 4.5 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP00068.1 - 3.7e-09 36.2 2.2 3.2e-05 23.6 0.2 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 RKP00068.1 - 2 9.3 4.9 31 5.7 0.0 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat Ipi1_N PF12333.8 RKP00069.1 - 7.5e-10 39.3 0.8 5.4e-09 36.6 0.0 3.0 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation ParE_toxin PF05016.15 RKP00069.1 - 8.8 7.0 7.1 1.1 9.9 0.3 3.1 4 0 0 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE bZIP_1 PF00170.21 RKP00072.1 - 1.7e-09 37.6 4.9 3.2e-09 36.8 4.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 RKP00072.1 - 5.7e-05 23.5 0.9 5.7e-05 23.5 0.9 6.3 8 1 1 9 9 9 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 RKP00072.1 - 6.4e-05 23.0 4.1 6.4e-05 23.0 4.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper SKA2 PF16740.5 RKP00073.1 - 0.079 12.7 2.8 0.2 11.4 0.0 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 EF-hand_1 PF00036.32 RKP00075.1 - 9.7e-30 99.9 13.5 6.4e-09 34.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKP00075.1 - 2e-28 98.6 9.4 1.3e-14 54.4 3.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RKP00075.1 - 4.1e-24 82.4 11.7 4.8e-08 32.3 0.2 4.5 3 1 2 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 RKP00075.1 - 1.6e-17 63.1 13.5 3e-08 33.4 1.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 RKP00075.1 - 2.4e-13 48.9 14.3 6e-05 22.3 0.1 4.5 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 RKP00075.1 - 6.6e-10 39.2 0.8 0.00079 19.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RKP00075.1 - 1.1e-07 31.8 5.3 0.00064 19.6 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 RKP00075.1 - 0.0025 17.8 1.2 0.24 11.3 0.0 3.0 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 RKP00075.1 - 0.017 15.5 3.1 0.62 10.4 0.2 2.4 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.6 RKP00075.1 - 0.017 15.0 2.6 1.2 9.0 0.2 2.4 2 1 0 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 RKP00075.1 - 0.02 15.2 3.5 0.46 10.9 0.3 2.6 2 1 0 2 2 2 0 EF-hand domain PhetRS_B1 PF18262.1 RKP00075.1 - 0.17 12.1 2.9 0.13 12.5 1.1 1.8 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Dockerin_1 PF00404.18 RKP00075.1 - 0.33 11.2 4.4 2.8 8.2 1.8 2.7 1 1 2 3 3 3 0 Dockerin type I domain MgtE_N PF03448.17 RKP00075.1 - 1.2 9.7 7.4 0.32 11.6 1.4 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain SOG2 PF10428.9 RKP00076.1 - 9.5 5.3 22.2 11 5.0 22.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDO_I PF05995.12 RKP00078.1 - 1.7e-37 128.3 0.2 8e-36 122.9 0.2 2.2 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 RKP00078.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 PCO_ADO Pkinase PF00069.25 RKP00079.1 - 5.9e-73 245.5 0.0 6.8e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00079.1 - 1.4e-40 139.2 0.0 1.7e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00079.1 - 7.4e-13 48.5 0.0 9.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP00079.1 - 8.4e-05 22.6 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP00079.1 - 0.00054 19.0 0.2 0.00066 18.7 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP00079.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RKP00079.1 - 0.0014 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 RKP00079.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RKP00079.1 - 0.067 12.0 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase BCDHK_Adom3 PF10436.9 RKP00080.1 - 2.4e-56 190.1 0.0 3.2e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RKP00080.1 - 8.2e-14 52.1 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RKP00080.1 - 0.0018 18.1 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1420 PF07220.11 RKP00080.1 - 0.03 12.9 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1420) DnaJ_CXXCXGXG PF00684.19 RKP00081.1 - 0.00055 20.2 51.2 0.077 13.4 10.3 4.6 1 1 3 4 4 4 4 DnaJ central domain LRR_4 PF12799.7 RKP00083.1 - 2.1e-06 27.9 0.3 0.16 12.5 0.0 3.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RKP00083.1 - 8.2e-05 22.4 2.0 3.8 7.8 0.1 5.5 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.7 RKP00083.1 - 0.039 13.8 0.5 0.082 12.8 0.5 1.5 1 0 0 1 1 1 0 F-box-like DUF1275 PF06912.11 RKP00084.1 - 1e-26 94.1 20.6 1.3e-26 93.7 20.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SNF5 PF04855.12 RKP00085.1 - 1.6e-39 136.1 0.0 2.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HDV_ag PF01517.18 RKP00085.1 - 1.4 8.6 5.6 1.7 8.4 4.6 1.5 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen Peptidase_S10 PF00450.22 RKP00086.1 - 2.2e-118 396.3 0.2 2.7e-118 396.0 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sde2_N_Ubi PF13019.6 RKP00087.1 - 9.2e-28 97.1 1.0 1.7e-27 96.2 1.0 1.5 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Peroxin-3 PF04882.12 RKP00087.1 - 1.5 7.7 3.7 2.1 7.3 3.7 1.2 1 0 0 1 1 1 0 Peroxin-3 E1-E2_ATPase PF00122.20 RKP00088.1 - 1.9e-47 161.1 0.8 1.9e-47 161.1 0.8 2.7 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RKP00088.1 - 3e-46 157.4 9.6 6.3e-46 156.4 5.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RKP00088.1 - 1.2e-21 77.9 0.4 7.5e-21 75.4 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKP00088.1 - 6e-19 67.5 0.3 4e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 RKP00088.1 - 1.5e-17 63.5 0.0 2.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKP00088.1 - 8.3e-07 29.0 2.6 1.1e-05 25.4 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RKP00088.1 - 1.6e-05 25.4 0.0 5.4e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IstB_IS21 PF01695.17 RKP00088.1 - 0.11 12.2 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RGS PF00615.19 RKP00089.1 - 0.0014 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Oxidored_q5_N PF01059.17 RKP00089.1 - 3.5 7.8 11.0 0.074 13.2 3.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Fasciclin PF02469.22 RKP00090.1 - 6.7e-23 81.3 0.0 5.7e-10 39.5 0.0 4.1 4 1 0 4 4 4 3 Fasciclin domain HTH_ParB PF17762.1 RKP00090.1 - 0.16 11.8 0.0 0.48 10.3 0.0 1.9 1 0 0 1 1 1 0 HTH domain found in ParB protein TAL_FSA PF00923.19 RKP00092.1 - 2.7e-87 292.8 0.7 4.1e-87 292.2 0.7 1.3 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF3767 PF12597.8 RKP00093.1 - 4.7e-18 64.9 0.4 4.9e-18 64.8 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Phage_holin_2_3 PF16080.5 RKP00093.1 - 1 9.2 4.3 1.4 8.8 0.2 2.2 1 1 1 2 2 2 0 Bacteriophage holin family HP1 DUF3449 PF11931.8 RKP00094.1 - 6.6e-66 221.6 0.0 6.8e-65 218.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 RKP00094.1 - 5.5e-15 55.7 0.0 9.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 RKP00094.1 - 3e-10 40.1 0.8 9e-09 35.4 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP00094.1 - 5.8e-07 29.7 1.2 0.00027 21.2 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RKP00094.1 - 8e-05 22.9 1.9 0.0019 18.5 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 RKP00094.1 - 0.011 16.5 0.8 1.4 10.0 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Jas PF16135.5 RKP00094.1 - 0.037 14.2 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf-LYAR PF08790.11 RKP00094.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-DBF PF07535.12 RKP00094.1 - 0.31 11.2 2.4 1.6 8.9 0.2 2.5 2 0 0 2 2 2 0 DBF zinc finger DEAD PF00270.29 RKP00095.1 - 5.3e-42 143.6 0.2 1.1e-41 142.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP00095.1 - 2.5e-31 108.3 0.0 1.1e-30 106.2 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 RKP00095.1 - 0.00038 20.2 0.3 0.00094 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RKP00095.1 - 0.0016 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKP00095.1 - 0.014 15.8 0.2 0.073 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RKP00095.1 - 0.038 14.3 0.0 0.09 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain GPI2 PF06432.11 RKP00096.1 - 4.9e-67 226.3 2.7 5.6e-67 226.1 2.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase YqhR PF11085.8 RKP00096.1 - 0.014 15.3 1.0 0.042 13.8 0.9 1.9 1 1 0 1 1 1 0 Conserved membrane protein YqhR DUF3932 PF13068.6 RKP00096.1 - 0.065 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) AAA PF00004.29 RKP00097.1 - 2.3e-27 96.0 0.0 2.2e-21 76.6 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RKP00097.1 - 3e-07 30.7 0.0 0.0014 18.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 RKP00097.1 - 1.5e-06 28.7 9.6 0.015 15.7 0.2 4.7 2 2 1 3 3 3 2 AAA ATPase domain NACHT PF05729.12 RKP00097.1 - 5.9e-06 26.3 0.4 0.78 9.6 0.0 3.5 2 1 1 3 3 3 2 NACHT domain AAA_5 PF07728.14 RKP00097.1 - 2.4e-05 24.4 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP00097.1 - 2.5e-05 24.6 0.1 2.2 8.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 RKP00097.1 - 0.0026 17.4 0.9 2.5 7.6 0.2 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 RKP00097.1 - 0.0033 17.8 0.1 0.8 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RKP00097.1 - 0.0043 16.8 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 RKP00097.1 - 0.0084 15.9 0.6 0.031 14.1 0.2 2.2 2 0 0 2 2 2 1 AAA+ lid domain RNA_helicase PF00910.22 RKP00097.1 - 0.014 15.7 0.0 0.35 11.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 RKP00097.1 - 0.019 15.4 0.2 9.3 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RKP00097.1 - 0.023 14.5 1.2 0.29 10.9 0.3 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 RKP00097.1 - 0.023 14.7 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFG1_ATPase PF03969.16 RKP00097.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_29 PF13555.6 RKP00097.1 - 0.027 14.2 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 RKP00097.1 - 0.029 14.2 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 RKP00097.1 - 0.032 13.5 0.1 0.097 11.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 RKP00097.1 - 0.04 13.7 0.5 0.093 12.4 0.1 1.8 2 0 0 2 2 2 0 Cytidylate kinase RuvB_N PF05496.12 RKP00097.1 - 0.075 12.8 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 RKP00097.1 - 0.088 12.1 0.2 3.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 RKP00097.1 - 0.11 13.1 0.1 5.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain LSM PF01423.22 RKP00098.1 - 5.7e-19 67.6 0.1 6.9e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 RKP00098.1 - 0.0028 17.2 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Hfq protein CN_hydrolase PF00795.22 RKP00099.1 - 2.3e-40 138.6 0.0 3.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 RKP00099.1 - 4e-22 78.5 0.0 3.8e-21 75.3 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 RKP00099.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Acetyltransf_1 PF00583.25 RKP00100.1 - 4.2e-10 39.9 0.0 6.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RKP00100.1 - 1.2e-07 31.7 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKP00100.1 - 2.7e-06 27.7 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKP00100.1 - 7.1e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Not1 PF04054.15 RKP00101.1 - 4.2e-122 407.6 0.0 1.4e-120 402.6 0.0 2.2 1 1 1 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 RKP00101.1 - 1.1e-84 283.3 0.1 2e-84 282.5 0.1 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 RKP00101.1 - 2.7e-52 176.7 0.0 9.1e-52 175.0 0.0 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 RKP00101.1 - 4.4e-49 166.2 1.0 9.4e-49 165.1 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 RKP00101.1 - 1.4e-35 122.6 0.2 3e-35 121.5 0.2 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat SCA7 PF08313.12 RKP00102.1 - 4.8e-20 71.2 0.5 7.5e-20 70.6 0.5 1.3 1 0 0 1 1 1 1 SCA7, zinc-binding domain Pkinase PF00069.25 RKP00103.1 - 7.8e-60 202.5 0.0 8.8e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00103.1 - 1.3e-47 162.2 0.0 1.6e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP00103.1 - 1.8e-06 27.0 0.0 3.5e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RKP00103.1 - 9e-05 21.9 0.0 0.00061 19.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like JmjC PF02373.22 RKP00104.1 - 9.7e-41 138.8 0.1 1.5e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 RKP00104.1 - 1.6e-09 37.5 0.3 3.9e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 jmjN domain Pkinase PF00069.25 RKP00105.1 - 4.2e-60 203.3 0.0 5e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00105.1 - 4.8e-28 98.2 0.0 6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKP00105.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP00105.1 - 0.038 12.9 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DcpS_C PF11969.8 RKP00106.1 - 6.1e-15 55.7 0.0 6.7e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RKP00106.1 - 1e-08 35.8 0.0 1.1e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain Rieske PF00355.26 RKP00107.1 - 1.5e-11 44.0 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 RKP00107.1 - 1.8e-07 31.5 0.1 3.7e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region tRNA-synt_1 PF00133.22 RKP00108.1 - 7e-206 685.1 0.0 1.4e-204 680.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RKP00108.1 - 6.1e-34 117.2 0.0 1.5e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RKP00108.1 - 8.2e-15 54.4 0.0 5.1e-07 28.8 0.0 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 RKP00108.1 - 6.6e-10 38.8 0.1 6.3e-07 29.1 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 RKP00108.1 - 0.0035 17.6 2.3 0.0035 17.6 2.3 2.5 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 RKP00108.1 - 0.15 11.4 0.0 0.44 9.8 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain AAA PF00004.29 RKP00109.1 - 3.2e-16 60.0 0.0 4.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP00109.1 - 1.4e-13 51.6 0.2 5.8e-13 49.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP00109.1 - 1.3e-07 31.9 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 RKP00109.1 - 1e-05 25.6 0.1 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 RKP00109.1 - 5.5e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP00109.1 - 0.00034 20.4 0.1 0.00084 19.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RKP00109.1 - 0.00063 19.1 0.0 0.00083 18.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 RKP00109.1 - 0.0035 16.9 0.0 0.041 13.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 RKP00109.1 - 0.0088 16.6 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zot PF05707.12 RKP00109.1 - 0.025 14.2 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.6 RKP00109.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RKP00109.1 - 0.073 13.1 0.1 1.4 8.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 RKP00109.1 - 0.085 12.1 0.0 0.67 9.1 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain ssDBP PF17878.1 RKP00109.1 - 0.11 12.7 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Single-stranded DNA-binding protein NACHT PF05729.12 RKP00109.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 NACHT domain DUF483 PF04467.12 RKP00111.1 - 0.0027 17.7 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF483) T2SSM PF04612.12 RKP00111.1 - 0.047 13.7 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Rap_GAP PF02145.15 RKP00112.1 - 5.7e-42 143.4 0.0 7.9e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP McyA_C PF12593.8 RKP00113.1 - 0.073 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal DUF3562 PF12085.8 RKP00113.1 - 6.9 6.4 9.0 2.1 8.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3562) WW PF00397.26 RKP00114.1 - 8.9e-10 38.5 3.3 2.6e-06 27.4 2.2 2.5 2 0 0 2 2 2 2 WW domain Baculo_p48 PF04878.13 RKP00114.1 - 0.064 12.2 0.9 0.1 11.5 0.9 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein Bap31_Bap29_C PF18035.1 RKP00114.1 - 0.08 13.0 0.3 0.08 13.0 0.3 3.9 3 1 1 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 RKP00114.1 - 0.12 11.9 23.8 0.078 12.6 13.1 2.5 1 1 1 2 2 2 0 Intermediate filament protein TadF PF16964.5 RKP00114.1 - 0.26 11.0 2.2 0.63 9.8 2.2 1.6 1 0 0 1 1 1 0 Putative tight adherence pilin protein F DUF3584 PF12128.8 RKP00114.1 - 0.37 8.3 27.4 1.1 6.7 27.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1515 PF07439.11 RKP00114.1 - 0.66 10.0 6.8 0.12 12.4 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) FSA_C PF10479.9 RKP00114.1 - 0.73 7.9 4.9 1.1 7.4 4.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Baculo_PEP_C PF04513.12 RKP00114.1 - 2.3 8.3 7.6 1.2 9.2 3.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.9 RKP00114.1 - 4.1 7.1 11.9 2.4 7.8 8.8 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.22 RKP00114.1 - 7.7 6.8 22.1 0.043 14.1 2.1 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MORN PF02493.20 RKP00116.1 - 1.6e-41 137.7 63.7 1.4e-07 31.0 2.9 8.9 10 0 0 10 10 10 8 MORN repeat BsuPI PF12690.7 RKP00116.1 - 0.081 13.0 0.5 0.28 11.2 0.0 2.1 3 0 0 3 3 3 0 Intracellular proteinase inhibitor PAC2 PF09754.9 RKP00117.1 - 2.2e-10 40.9 0.0 2.7e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 PAC2 family DUF2353 PF09789.9 RKP00118.1 - 0.012 15.0 1.2 0.017 14.5 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3450 PF11932.8 RKP00118.1 - 0.031 13.6 8.0 0.056 12.8 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 RKP00118.1 - 0.11 12.9 7.0 0.18 12.2 7.0 1.2 1 0 0 1 1 1 0 Fez1 Macoilin PF09726.9 RKP00118.1 - 0.19 10.2 0.6 0.27 9.8 0.6 1.1 1 0 0 1 1 1 0 Macoilin family HIP1_clath_bdg PF16515.5 RKP00118.1 - 0.25 11.9 7.1 5.7 7.6 0.8 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 RKP00118.1 - 0.3 9.9 5.5 0.43 9.4 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 RKP00118.1 - 0.33 11.3 7.8 0.41 11.0 6.0 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 RKP00118.1 - 0.71 8.9 4.5 1.2 8.2 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 RKP00118.1 - 0.78 9.5 10.6 1.4 8.7 10.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 RKP00118.1 - 1.1 8.6 8.9 1.8 7.9 8.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 RKP00118.1 - 1.5 8.2 8.2 2.2 7.6 8.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 RKP00118.1 - 2 8.5 8.1 3.8 7.6 8.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Kinetochor_Ybp2 PF08568.10 RKP00119.1 - 0.077 11.5 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Pet127 PF08634.10 RKP00120.1 - 6.9e-52 176.6 0.0 7.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial protein Pet127 MAGE PF01454.19 RKP00122.1 - 1.5e-07 31.3 0.0 1.5e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 MAGE family FHA PF00498.26 RKP00123.1 - 1.1e-13 51.3 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RKP00123.1 - 1.2e-06 28.7 0.0 0.00037 20.7 0.0 2.1 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain T2SS-T3SS_pil_N PF13629.6 RKP00123.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Pilus formation protein N terminal region DCP1 PF06058.13 RKP00124.1 - 2.3e-22 79.1 0.0 2.5e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family Ribosomal_L32e PF01655.18 RKP00125.1 - 3.7e-42 143.1 0.0 4.4e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PRP21_like_P PF12230.8 RKP00126.1 - 6.6e-27 94.8 0.0 8.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 RKP00126.1 - 7.3e-25 86.7 0.1 1.7e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 RKP00126.1 - 0.0096 15.5 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger ILVD_EDD PF00920.21 RKP00127.1 - 6e-213 708.1 1.2 7.4e-213 707.8 1.2 1.0 1 0 0 1 1 1 1 Dehydratase family Vps5 PF09325.10 RKP00128.1 - 7.1e-07 29.0 0.6 7.1e-07 29.0 0.6 1.4 2 0 0 2 2 2 1 Vps5 C terminal like Trypsin_2 PF13365.6 RKP00128.1 - 0.023 15.6 0.8 0.11 13.5 0.0 2.4 2 0 0 2 2 2 0 Trypsin-like peptidase domain Brix PF04427.18 RKP00129.1 - 6e-37 127.6 0.0 7.2e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Brix domain ABC_tran_CTD PF16326.5 RKP00130.1 - 0.44 10.8 5.9 11 6.3 0.9 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Prominin PF05478.11 RKP00131.1 - 3.9e-11 41.7 0.0 6e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Prominin Tweety PF04906.13 RKP00131.1 - 1.7e-05 23.7 4.8 0.0058 15.4 0.1 2.5 2 0 0 2 2 2 2 Tweety Baculo_PEP_C PF04513.12 RKP00131.1 - 0.0043 17.1 29.9 0.098 12.7 7.9 4.5 4 0 0 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 RKP00131.1 - 0.03 14.2 0.5 0.46 10.3 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SUR7 PF06687.12 RKP00131.1 - 0.05 13.2 11.7 0.023 14.3 2.0 2.7 2 0 0 2 2 2 0 SUR7/PalI family DUF2207 PF09972.9 RKP00131.1 - 0.19 10.5 3.3 0.18 10.5 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DASH_Duo1 PF08651.10 RKP00131.1 - 0.4 10.5 1.8 4.7 7.1 0.2 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF1664 PF07889.12 RKP00131.1 - 0.45 10.6 2.6 27 4.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 RKP00131.1 - 0.97 9.7 7.2 4.7 7.5 0.1 4.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 RKP00131.1 - 6.6 7.3 20.6 7.4 7.1 1.7 5.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Piwi PF02171.17 RKP00133.1 - 4.2e-96 321.7 0.0 5.6e-96 321.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RKP00133.1 - 9.1e-17 61.1 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 RKP00133.1 - 1.4e-14 54.8 0.0 2.7e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RKP00133.1 - 6.6e-13 48.1 0.0 1.6e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 RKP00133.1 - 9.4e-11 41.8 0.0 2.4e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 RKP00133.1 - 3.5e-09 36.9 0.0 7.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain BK_channel_a PF03493.18 RKP00134.1 - 2.9e-24 85.1 0.0 3.1e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RKP00134.1 - 2.9e-11 43.2 2.0 2.9e-11 43.2 2.0 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RKP00134.1 - 7.1e-06 25.4 14.5 7.1e-06 25.4 14.5 1.7 2 0 0 2 2 2 1 Ion transport protein Prok-E2_B PF14461.6 RKP00134.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Lig_chan PF00060.26 RKP00134.1 - 0.4 10.5 4.1 0.094 12.6 0.5 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel DUF2975 PF11188.8 RKP00134.1 - 5.4 6.9 10.8 0.17 11.7 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Rubredoxin_2 PF18073.1 RKP00135.1 - 1.5 8.6 4.7 11 5.8 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin metal binding domain cNMP_binding PF00027.29 RKP00136.1 - 1.9e-45 152.9 0.1 6e-22 77.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 RKP00136.1 - 1.9e-14 53.0 3.1 3.9e-14 52.0 3.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF1961 PF09224.11 RKP00136.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) RXT2_N PF08595.11 RKP00136.1 - 0.045 13.8 2.1 0.091 12.8 2.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 RKP00136.1 - 0.069 12.3 9.8 0.097 11.8 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 RKP00136.1 - 0.095 13.1 6.2 0.22 11.9 6.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 RKP00136.1 - 0.096 13.1 16.5 0.23 11.8 16.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RKP00136.1 - 0.12 12.0 8.8 0.22 11.2 8.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RKP00136.1 - 0.22 10.8 9.7 0.34 10.2 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 RKP00136.1 - 0.26 11.1 2.5 0.37 10.6 2.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 RKP00136.1 - 0.3 10.7 2.6 0.51 10.0 2.6 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RKP00136.1 - 2 6.6 4.5 2.5 6.3 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RKP00136.1 - 2 6.4 9.2 2.9 5.9 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 RKP00136.1 - 3.4 6.1 4.3 4.6 5.7 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Actin PF00022.19 RKP00137.1 - 7.1e-123 410.2 0.0 7.6e-122 406.8 0.0 1.9 1 1 0 1 1 1 1 Actin Mit_ribos_Mrp51 PF11709.8 RKP00138.1 - 1.7e-08 34.5 0.4 4.1e-06 26.6 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein subunit SRR1 PF07985.12 RKP00139.1 - 3.1e-09 36.7 0.4 7.5e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 SRR1 Ribosomal_L28e PF01778.17 RKP00140.1 - 1.9e-33 115.6 0.2 1.9e-33 115.6 0.2 2.3 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 RKP00140.1 - 2.3e-21 76.3 16.3 2.3e-21 76.3 16.3 1.8 2 0 0 2 2 2 1 Mak16 protein C-terminal region Fucose_iso_N2 PF07882.12 RKP00140.1 - 0.076 12.6 0.6 0.14 11.8 0.6 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain GTP_EFTU PF00009.27 RKP00142.1 - 8.8e-40 136.3 0.0 1.3e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RKP00142.1 - 2e-33 115.1 1.5 5.5e-33 113.6 0.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RKP00142.1 - 4.3e-07 30.2 0.2 9.6e-07 29.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RKP00142.1 - 0.0049 16.9 0.2 0.059 13.5 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 RKP00142.1 - 0.058 13.3 0.2 0.21 11.5 0.2 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Tim17 PF02466.19 RKP00143.1 - 6.2e-32 110.3 8.2 7.5e-32 110.0 8.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 RKP00143.1 - 0.18 11.9 4.2 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper Tfb2 PF03849.14 RKP00144.1 - 2e-131 438.2 0.0 2.3e-131 438.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 RKP00144.1 - 4e-22 78.4 0.7 4e-22 78.4 0.7 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 RKP00144.1 - 0.0074 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TB2_DP1_HVA22 PF03134.19 RKP00145.1 - 2.1e-23 82.0 4.7 2.7e-23 81.7 4.7 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bap31 PF05529.12 RKP00145.1 - 0.16 11.9 1.3 0.2 11.5 1.3 1.1 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Pex14_N PF04695.13 RKP00146.1 - 0.0026 18.4 14.1 0.01 16.5 14.1 2.0 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 RKP00146.1 - 0.0089 16.2 2.2 0.016 15.4 2.2 1.3 1 0 0 1 1 1 1 DDHD domain SpoIIP PF07454.11 RKP00146.1 - 0.014 14.9 6.3 0.021 14.3 6.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 RKP00146.1 - 0.043 13.8 31.4 0.072 13.1 31.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 RKP00146.1 - 0.082 13.0 2.5 0.15 12.1 2.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CCDC53 PF10152.9 RKP00146.1 - 0.24 11.8 9.9 0.59 10.5 9.9 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex NARP1 PF12569.8 RKP00146.1 - 0.36 9.7 7.6 0.53 9.1 7.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tim54 PF11711.8 RKP00146.1 - 0.36 9.6 9.0 0.57 8.9 9.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4770 PF15994.5 RKP00146.1 - 0.65 10.2 11.2 1 9.5 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4407 PF14362.6 RKP00146.1 - 0.76 9.1 13.3 0.66 9.3 8.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM60A PF15396.6 RKP00146.1 - 0.81 9.7 5.9 1.2 9.0 5.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 RKP00146.1 - 1.5 7.0 22.9 2.1 6.5 22.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF702 PF05142.12 RKP00146.1 - 1.7 9.1 11.4 3.5 8.1 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SLC12 PF03522.15 RKP00146.1 - 2.3 7.1 9.4 3.4 6.6 9.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 RKP00146.1 - 2.9 7.6 7.9 4.9 6.8 7.9 1.2 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 RKP00146.1 - 3.3 6.6 6.9 6.5 5.6 6.9 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 RKP00146.1 - 3.6 6.3 15.4 5.9 5.5 15.4 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 RKP00146.1 - 3.9 6.9 5.4 6.9 6.1 5.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 EPL1 PF10513.9 RKP00146.1 - 4 7.8 13.4 6.9 7.0 13.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF719 PF05334.13 RKP00146.1 - 4.4 7.5 11.9 28 4.9 12.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DNApol_Exo PF18136.1 RKP00146.1 - 4.5 6.3 8.6 8.1 5.5 8.6 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DUF4050 PF13259.6 RKP00146.1 - 4.8 7.5 12.4 38 4.5 10.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) MMR1 PF08505.10 RKP00146.1 - 5 7.3 17.0 7.9 6.7 17.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hydin_ADK PF17213.3 RKP00146.1 - 5.7 7.2 11.9 13 6.0 11.9 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 RKP00146.1 - 6.3 6.3 43.5 9.5 5.8 43.5 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 RKP00146.1 - 6.7 5.3 12.1 12 4.5 12.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDM10 PF12519.8 RKP00146.1 - 7.3 5.3 8.2 11 4.8 8.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 eIF-3_zeta PF05091.12 RKP00146.1 - 8.6 5.2 18.9 13 4.6 18.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 RKP00146.1 - 9.6 6.2 8.6 16 5.5 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AlaDh_PNT_N PF05222.15 RKP00147.1 - 1.4e-25 90.1 0.0 3.1e-25 89.1 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DEP PF00610.21 RKP00147.1 - 0.092 12.8 0.0 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SET PF00856.28 RKP00149.1 - 0.064 13.6 0.0 0.16 12.3 0.0 1.8 1 1 0 1 1 1 0 SET domain zf-C2H2 PF00096.26 RKP00150.1 - 1.6e-08 34.5 3.5 0.0016 18.8 0.2 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP00150.1 - 6.6e-07 29.6 3.8 0.0092 16.7 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RKP00150.1 - 9.9e-06 25.4 1.6 0.026 14.5 0.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RKP00150.1 - 0.0015 18.8 0.8 0.0016 18.7 0.8 1.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 RKP00150.1 - 0.0021 18.4 0.9 0.04 14.3 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 RKP00150.1 - 0.095 12.4 1.5 0.14 11.8 0.2 1.8 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 RKP00150.1 - 0.1 12.4 0.1 0.1 12.4 0.1 1.9 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RKP00150.1 - 0.18 12.3 4.0 0.28 11.7 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger double domain RRM_1 PF00076.22 RKP00151.1 - 9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1283 PF06932.11 RKP00151.1 - 0.02 15.1 1.7 0.02 15.1 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) DUF4140 PF13600.6 RKP00151.1 - 0.049 14.1 0.2 5.8 7.4 0.0 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mpp10 PF04006.12 RKP00151.1 - 2.9 6.2 35.1 0.091 11.2 14.3 2.2 2 0 0 2 2 2 0 Mpp10 protein CoA_binding_3 PF13727.6 RKP00152.1 - 1.3 9.0 10.2 0.24 11.4 6.2 1.7 2 0 0 2 2 2 0 CoA-binding domain FtsK_4TM PF13491.6 RKP00152.1 - 6.3 6.5 14.0 2.9 7.6 0.4 2.4 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE NUDIX PF00293.28 RKP00153.1 - 2.3e-05 24.4 0.2 1.8 8.6 0.0 3.6 3 0 0 3 3 3 3 NUDIX domain PCNA_N PF00705.18 RKP00154.1 - 2.7e-54 182.2 3.0 5.6e-54 181.2 2.6 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 RKP00154.1 - 2.8e-54 182.7 0.0 7.9e-54 181.3 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 RKP00154.1 - 2.5e-06 27.1 0.0 3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 DUF863 PF05904.11 RKP00154.1 - 0.26 9.7 0.3 0.28 9.6 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) WD40 PF00400.32 RKP00155.1 - 6.9e-14 52.0 4.1 0.046 14.6 0.2 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat HEPN_RES_NTD1 PF18870.1 RKP00155.1 - 0.012 15.8 1.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 HEPN/RES N-terminal domain 1 DsbC_N PF10411.9 RKP00155.1 - 0.077 12.5 0.0 1 8.8 0.0 2.8 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus Nop53 PF07767.11 RKP00156.1 - 6.4e-41 141.1 15.9 8.8e-41 140.6 15.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Aldo_ket_red PF00248.21 RKP00157.1 - 5.1e-45 153.9 0.0 6.4e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3591 PF12157.8 RKP00158.1 - 2e-111 372.8 0.0 1.2e-79 268.1 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) Rsm22 PF09243.10 RKP00159.1 - 2.6e-28 99.1 0.6 6.3e-14 51.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 TPR_2 PF07719.17 RKP00161.1 - 2.6e-09 36.5 0.0 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP00161.1 - 1.8e-07 30.7 0.0 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RKP00161.1 - 2e-07 31.4 0.0 3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP00161.1 - 7.1e-06 25.7 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKP00161.1 - 7.4e-06 26.4 0.0 0.037 14.8 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKP00161.1 - 2.3e-05 25.0 0.0 0.38 11.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP00161.1 - 9.4e-05 22.3 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKP00161.1 - 0.00094 18.8 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 RKP00161.1 - 0.0015 18.8 0.1 0.016 15.6 0.0 2.5 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP00161.1 - 0.0016 18.6 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 RKP00161.1 - 0.0022 18.4 0.0 0.0028 18.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 RKP00161.1 - 0.0036 17.6 0.1 0.0055 17.0 0.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat ChAPs PF09295.10 RKP00161.1 - 0.0061 15.6 0.0 0.0074 15.3 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.6 RKP00161.1 - 0.039 14.2 0.1 0.62 10.4 0.1 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP00161.1 - 0.097 12.6 0.1 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 RKP00161.1 - 0.18 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) Lipase_3 PF01764.25 RKP00162.1 - 1.2e-14 54.4 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 RKP00162.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.32 RKP00163.1 - 3.8e-13 49.7 6.1 0.00082 20.1 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00163.1 - 1.1e-05 25.7 0.1 0.019 15.3 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 RKP00163.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) PPR PF01535.20 RKP00164.1 - 2.1e-05 24.5 0.0 2.2 8.7 0.0 4.4 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 RKP00164.1 - 0.00024 21.1 0.2 1.4 9.0 0.0 3.6 5 0 0 5 5 5 2 Pentatricopeptide repeat domain TPR_15 PF13429.6 RKP00164.1 - 0.0014 17.9 8.4 0.21 10.8 1.8 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat PPR_2 PF13041.6 RKP00164.1 - 0.0058 16.8 0.0 15 5.9 0.0 4.2 4 1 1 5 5 5 1 PPR repeat family QslA_E PF18226.1 RKP00164.1 - 0.025 14.5 0.7 2 8.4 0.0 2.7 2 0 0 2 2 2 0 LasR-specific antiactivator QslA chain E TPR_2 PF07719.17 RKP00164.1 - 0.13 12.5 3.7 47 4.5 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKP00164.1 - 2.7 8.8 9.6 19 6.2 1.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 RKP00165.1 - 3.9e-08 33.3 12.5 0.0003 21.1 4.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP00165.1 - 5.3e-07 29.9 11.9 0.0015 19.2 3.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP00165.1 - 3.2e-06 27.3 0.5 3.2e-06 27.3 0.5 2.3 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RKP00165.1 - 0.00017 21.8 1.0 0.063 13.6 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RKP00165.1 - 0.0024 17.6 4.1 0.0024 17.6 4.1 2.6 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 RKP00165.1 - 0.035 14.4 5.9 0.66 10.3 1.9 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 RKP00165.1 - 0.061 13.7 2.7 1.9 9.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RKP00165.1 - 0.084 12.7 1.4 0.084 12.7 1.4 2.6 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 RKP00165.1 - 0.092 12.6 1.2 0.092 12.6 1.2 1.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 RKP00165.1 - 0.11 12.4 1.0 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 RKP00165.1 - 0.55 10.5 7.5 0.18 12.1 3.5 2.1 1 1 1 2 2 2 0 zinc-ribbon zf-BED PF02892.15 RKP00165.1 - 1.6 8.8 8.2 0.25 11.4 0.9 2.1 1 1 1 2 2 2 0 BED zinc finger WH2 PF02205.20 RKP00170.1 - 1.9e-08 33.8 0.1 4.1e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 WH2 motif ASH PF15780.5 RKP00172.1 - 2e-13 50.3 9.6 0.0097 16.1 0.0 11.3 12 0 0 12 12 12 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RKP00172.1 - 1e-08 35.0 0.0 0.0038 17.0 0.0 6.0 8 0 0 8 8 8 2 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RKP00172.1 - 0.00019 21.6 1.4 1.2 9.4 0.0 5.3 5 0 0 5 5 5 1 Transmembrane protein 131-like MYCBPAP PF14646.6 RKP00172.1 - 0.016 14.1 0.0 0.59 9.0 0.0 2.9 3 0 0 3 3 3 0 MYCBP-associated protein family DUF723 PF05265.13 RKP00172.1 - 0.053 13.5 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF723) DUF756 PF05506.12 RKP00172.1 - 0.36 11.8 5.3 1 10.3 0.4 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF756) YqeY PF09424.10 RKP00173.1 - 6.1e-23 81.5 2.9 7.9e-23 81.1 2.9 1.1 1 0 0 1 1 1 1 Yqey-like protein ABC_transp_aux PF09822.9 RKP00175.1 - 7.6e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system PPR_2 PF13041.6 RKP00176.1 - 2e-25 88.7 0.0 3.2e-07 30.4 0.0 7.1 3 2 5 8 8 8 6 PPR repeat family PPR PF01535.20 RKP00176.1 - 1.2e-24 84.8 0.0 6.8e-06 26.0 0.0 7.2 7 0 0 7 7 7 5 PPR repeat PPR_3 PF13812.6 RKP00176.1 - 7.1e-19 67.6 0.0 1.1e-05 25.3 0.0 6.6 4 3 4 8 8 8 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 RKP00176.1 - 5.4e-16 58.0 0.0 0.00016 21.3 0.1 5.5 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 RKP00176.1 - 2.5e-14 53.1 0.5 2e-06 27.3 0.0 3.5 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 RKP00176.1 - 3.7e-05 24.1 7.9 0.054 14.0 0.1 4.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKP00176.1 - 0.00046 20.0 3.4 3.2 8.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKP00176.1 - 0.054 13.8 7.4 18 5.7 0.0 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP00176.1 - 0.46 10.4 5.6 19 5.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DinB_2 PF12867.7 RKP00176.1 - 0.81 10.2 9.5 0.32 11.5 4.6 2.9 2 1 0 2 2 2 0 DinB superfamily Sec6 PF06046.13 RKP00177.1 - 8.8e-123 410.7 0.0 1.2e-122 410.2 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 NPV_P10 PF05531.12 RKP00177.1 - 0.015 15.7 1.3 7.7 7.1 0.0 4.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Vps53_N PF04100.12 RKP00177.1 - 0.053 12.5 1.4 0.11 11.4 0.3 2.0 2 0 0 2 2 2 0 Vps53-like, N-terminal RIH_assoc PF08454.11 RKP00177.1 - 0.067 13.1 0.5 0.28 11.0 0.2 2.3 2 0 0 2 2 2 0 RyR and IP3R Homology associated MCU PF04678.13 RKP00177.1 - 0.082 13.0 1.6 0.17 12.0 0.2 2.4 2 2 0 2 2 2 0 Mitochondrial calcium uniporter DUF883 PF05957.13 RKP00177.1 - 0.16 12.6 4.9 23 5.7 0.1 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF4745 PF15923.5 RKP00177.1 - 0.44 10.5 1.8 14 5.7 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4745) WD40 PF00400.32 RKP00178.1 - 0.093 13.6 0.8 3.5 8.6 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Bromodomain PF00439.25 RKP00179.1 - 6.8e-29 99.8 0.0 1.3e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Bromodomain PKcGMP_CC PF16808.5 RKP00180.1 - 0.18 11.7 0.9 0.42 10.5 0.9 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase UPF0242 PF06785.11 RKP00180.1 - 0.22 11.6 3.9 0.29 11.2 3.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TBCA PF02970.16 RKP00180.1 - 1 9.7 6.4 0.31 11.4 2.3 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF4200 PF13863.6 RKP00180.1 - 1.8 9.0 9.8 15 6.0 10.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF737 PF05300.11 RKP00180.1 - 1.9 8.8 13.5 3.6 7.9 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PI3_PI4_kinase PF00454.27 RKP00181.1 - 6.6e-46 157.2 0.0 9.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TMEM135_C_rich PF15982.5 RKP00182.1 - 2.3e-10 41.2 0.1 4.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Mem_trans PF03547.18 RKP00182.1 - 0.065 11.6 0.5 0.12 10.7 0.5 1.3 1 0 0 1 1 1 0 Membrane transport protein Pkinase PF00069.25 RKP00183.1 - 1.9e-59 201.2 0.0 2.2e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00183.1 - 1.5e-44 152.3 0.0 1.9e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP00183.1 - 1.9e-06 26.9 0.0 2.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKP00183.1 - 0.00026 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP00183.1 - 0.0024 17.8 0.1 0.0077 16.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKP00183.1 - 0.0033 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RKP00183.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RKP00183.1 - 0.051 12.9 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MPP6 PF10175.9 RKP00185.1 - 5.7e-07 30.1 1.6 1.4e-06 28.9 0.1 2.1 1 1 1 2 2 2 1 M-phase phosphoprotein 6 Presenilin PF01080.17 RKP00185.1 - 1.2 7.9 2.0 1.4 7.6 2.0 1.2 1 0 0 1 1 1 0 Presenilin PVL_ORF50 PF07768.11 RKP00185.1 - 1.3 9.4 4.7 2.6 8.4 4.7 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family MTS PF05175.14 RKP00186.1 - 2.4e-06 27.2 0.1 2.8e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RKP00186.1 - 5.9e-05 23.7 0.1 0.00011 22.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RKP00186.1 - 8.6e-05 22.1 0.0 0.00066 19.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RKP00186.1 - 0.002 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP00186.1 - 0.011 16.5 0.0 0.034 14.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain rRNA_methylase PF06962.12 RKP00186.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative rRNA methylase Methyltransf_24 PF13578.6 RKP00186.1 - 0.044 14.8 0.0 0.087 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RKP00186.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATP_bind_1 PF03029.17 RKP00187.1 - 1.6e-77 260.5 0.0 2e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 RKP00187.1 - 6.3e-05 23.3 0.0 0.0025 18.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 RKP00187.1 - 0.021 15.0 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 RKP00187.1 - 0.083 13.0 0.0 0.36 10.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase CLP1_P PF16575.5 RKP00187.1 - 0.11 12.3 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 RKP00187.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RKP00187.1 - 0.18 12.4 0.0 0.79 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 RKP00189.1 - 2.3e-11 43.6 12.2 3e-11 43.2 12.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 RKP00189.1 - 0.086 13.2 6.0 0.27 11.6 1.5 2.2 2 0 0 2 2 2 0 Opy2 protein Rep_fac-A_C PF08646.10 RKP00189.1 - 2.1 8.1 7.5 2.5 7.8 7.5 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain UMP1 PF05348.11 RKP00190.1 - 1.7e-24 86.3 0.1 1.8e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 RNB PF00773.19 RKP00191.1 - 9.9e-43 146.7 0.0 1.1e-42 146.6 0.0 1.0 1 0 0 1 1 1 1 RNB domain Pribosyl_synth PF14572.6 RKP00192.1 - 9.4e-40 136.6 1.4 4.6e-33 114.8 0.7 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 RKP00192.1 - 1.9e-37 127.7 0.0 6.1e-37 126.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 RKP00192.1 - 3.3e-15 56.0 0.1 8e-15 54.7 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain RdRP_2 PF00978.21 RKP00192.1 - 0.13 11.1 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase WD40 PF00400.32 RKP00194.1 - 1.1e-22 79.9 8.3 2.3e-07 31.4 1.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00194.1 - 1.9e-08 34.5 0.0 0.36 11.2 0.0 4.5 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RKP00194.1 - 0.14 12.7 3.9 13 6.4 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain MarC PF01914.17 RKP00194.1 - 1.6 8.0 4.9 3.3 7.0 4.9 1.4 1 0 0 1 1 1 0 MarC family integral membrane protein PCO_ADO PF07847.12 RKP00195.1 - 6.5e-21 74.7 0.1 4.4e-14 52.4 0.0 2.5 2 1 0 2 2 2 2 PCO_ADO Mito_fiss_reg PF05308.11 RKP00195.1 - 1.4 9.0 14.1 0.17 12.0 0.3 2.8 3 0 0 3 3 3 0 Mitochondrial fission regulator GIT_SHD PF08518.11 RKP00196.1 - 2.6e-21 74.9 4.1 1e-10 41.1 0.2 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 RKP00196.1 - 0.00018 21.6 1.6 0.00018 21.6 1.6 2.5 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF3584 PF12128.8 RKP00196.1 - 0.0012 16.5 11.9 0.0027 15.3 11.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ATP-synt_D PF01813.17 RKP00196.1 - 0.19 11.5 4.2 0.48 10.2 3.4 2.1 1 1 0 1 1 1 0 ATP synthase subunit D GAS PF13851.6 RKP00196.1 - 0.93 8.8 17.6 0.051 12.9 2.7 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2408 PF10303.9 RKP00196.1 - 1.3 9.6 3.8 1.3 9.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) KxDL PF10241.9 RKP00196.1 - 2.2 8.6 8.3 0.91 9.8 2.4 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein ArAE_2_N PF10337.9 RKP00196.1 - 2.4 7.1 5.2 5.8 5.8 5.2 1.6 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Atg14 PF10186.9 RKP00196.1 - 7.1 5.6 9.5 1.6 7.7 4.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 RKP00196.1 - 9.6 6.3 7.5 3.9 7.5 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GIT_SHD PF08518.11 RKP00197.1 - 3.1e-20 71.5 4.5 2.9e-09 36.4 0.0 2.9 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT ATG16 PF08614.11 RKP00197.1 - 7.3e-05 23.1 24.2 7.3e-05 23.1 24.2 3.5 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 RKP00197.1 - 0.00036 18.5 21.5 0.00075 17.5 21.5 1.4 1 0 0 1 1 1 1 Myosin tail GIT1_C PF12205.8 RKP00197.1 - 0.00084 19.4 0.0 0.00084 19.4 0.0 3.6 3 1 1 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF724 PF05266.14 RKP00197.1 - 0.0066 16.3 10.9 0.0066 16.3 10.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 RKP00197.1 - 0.027 12.4 1.7 0.043 11.7 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.20 RKP00197.1 - 0.042 13.2 24.0 0.098 12.0 23.7 1.7 1 1 0 1 1 1 0 Tropomyosin RRF_GI PF12614.8 RKP00197.1 - 0.051 13.7 1.4 0.13 12.4 1.4 1.7 1 0 0 1 1 1 0 Ribosome recycling factor FPP PF05911.11 RKP00197.1 - 0.29 9.3 16.3 0.048 11.9 12.2 1.7 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1706 PF08020.11 RKP00197.1 - 0.4 10.6 4.1 0.77 9.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) EzrA PF06160.12 RKP00197.1 - 0.42 8.7 21.5 3.2 5.8 21.3 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Vir_act_alpha_C PF10400.9 RKP00197.1 - 2.2 9.0 16.6 4.1 8.2 11.9 3.5 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF3584 PF12128.8 RKP00197.1 - 3.7 4.9 23.2 8.2 3.8 23.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 RKP00197.1 - 3.9 6.3 27.1 0.26 10.1 4.7 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 RKP00197.1 - 4.1 7.4 23.6 2.6 8.1 6.8 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_UL6 PF01763.16 RKP00197.1 - 4.7 5.6 10.2 8.5 4.8 9.4 1.8 1 1 0 1 1 1 0 Herpesvirus UL6 like FlaC_arch PF05377.11 RKP00197.1 - 5.5 7.5 8.4 22 5.5 1.0 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Tup_N PF08581.10 RKP00197.1 - 8.3 6.8 20.0 8.6 6.7 4.1 3.1 1 1 0 2 2 2 0 Tup N-terminal SMC_N PF02463.19 RKP00198.1 - 7.7e-66 221.7 0.0 1.5e-65 220.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 RKP00198.1 - 6.2e-19 68.4 0.0 4.8e-18 65.6 0.0 2.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 RKP00198.1 - 2.2e-16 61.0 2.2 2.2e-16 61.0 2.2 5.0 4 1 0 4 4 4 1 AAA domain AAA_21 PF13304.6 RKP00198.1 - 1.4e-10 41.5 0.2 7.2e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RKP00198.1 - 5.2e-06 26.4 0.0 0.0002 21.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 RKP00198.1 - 0.00036 20.2 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 RKP00198.1 - 0.0061 17.1 14.5 0.21 12.1 0.0 5.0 3 2 0 3 3 3 2 ABC transporter FlaC_arch PF05377.11 RKP00198.1 - 0.24 11.8 8.8 1.8 9.0 1.9 5.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) APG6 PF04111.12 RKP00199.1 - 2.3e-30 105.9 0.0 2.6e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Apg6 BARA domain V-ATPase_C PF03223.15 RKP00200.1 - 6e-109 364.8 0.0 7.2e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF5443 PF17518.2 RKP00200.1 - 0.16 10.9 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5443) S10_plectin PF03501.15 RKP00201.1 - 8.9e-38 128.3 0.0 1.1e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M24 PF00557.24 RKP00203.1 - 0.00041 20.1 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_31 PF01055.26 RKP00204.1 - 3.3e-126 422.0 0.4 4e-126 421.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 RKP00204.1 - 1.5e-19 70.0 0.3 7.1e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Coprogen_oxidas PF01218.18 RKP00205.1 - 1.5e-128 427.7 0.0 1.7e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase FKBP_C PF00254.28 RKP00206.1 - 3e-31 107.6 0.0 3.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_hydro_26 PF02156.15 RKP00207.1 - 2.6e-07 30.4 1.4 0.0021 17.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 RKP00207.1 - 0.028 13.9 0.1 0.078 12.5 0.1 1.8 1 0 0 1 1 1 0 EF hand 7TM_GPCR_Sri PF10327.9 RKP00207.1 - 0.21 10.8 0.1 0.3 10.2 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri EF-hand_1 PF00036.32 RKP00207.1 - 0.24 11.0 0.3 0.61 9.8 0.3 1.7 1 0 0 1 1 1 0 EF hand COX6B PF02297.17 RKP00208.1 - 6.6e-14 51.9 0.6 1.6e-13 50.7 0.6 1.6 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb SelP_N PF04592.14 RKP00209.1 - 4.4 6.6 11.3 8.4 5.7 11.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AMP-binding PF00501.28 RKP00210.1 - 1.2e-69 234.9 0.0 1.5e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKP00210.1 - 9.6e-08 32.9 0.0 2.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1640 PF07798.11 RKP00211.1 - 9.7e-47 159.3 0.1 1.1e-46 159.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FTA4 PF13093.6 RKP00211.1 - 0.018 15.0 1.0 0.021 14.7 1.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Vac14_Fig4_bd PF11916.8 RKP00211.1 - 0.073 12.7 0.1 2.4 7.8 0.0 2.5 3 0 0 3 3 3 0 Vacuolar protein 14 C-terminal Fig4p binding Fez1 PF06818.15 RKP00211.1 - 0.082 13.4 3.6 0.11 13.0 3.0 1.4 1 1 0 1 1 1 0 Fez1 TFIID_NTD2 PF04494.15 RKP00211.1 - 0.086 13.1 0.2 17 5.6 0.2 2.2 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain FlaC_arch PF05377.11 RKP00211.1 - 0.25 11.8 1.9 32 5.0 0.0 3.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF410 PF04190.13 RKP00212.1 - 6.4e-46 157.2 0.0 8.6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_20 PF14561.6 RKP00212.1 - 2.6 8.5 13.8 0.76 10.1 1.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat HTH_18 PF12833.7 RKP00213.1 - 0.069 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain AAA PF00004.29 RKP00215.1 - 7.8e-17 61.9 0.0 1.8e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 RKP00215.1 - 2.1e-12 47.3 0.0 3.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 RKP00215.1 - 7.5e-12 45.3 0.0 1.2e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 RKP00215.1 - 7.8e-07 29.2 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 RKP00215.1 - 3.7e-06 27.4 0.1 0.00066 20.1 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 RKP00215.1 - 2.8e-05 24.1 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKP00215.1 - 3.2e-05 23.7 0.1 0.00012 21.9 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 RKP00215.1 - 6.9e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKP00215.1 - 9.4e-05 22.7 0.1 0.0049 17.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RKP00215.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP00215.1 - 0.0012 18.6 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 RKP00215.1 - 0.0013 18.7 0.0 0.0046 17.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 RKP00215.1 - 0.0042 17.4 0.0 0.02 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RKP00215.1 - 0.0042 16.3 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 RKP00215.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 RKP00215.1 - 0.0086 16.4 0.1 0.022 15.1 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 RKP00215.1 - 0.01 15.8 0.0 0.03 14.3 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DNA_pol3_gamma3 PF12169.8 RKP00215.1 - 0.012 15.5 0.2 0.03 14.2 0.1 1.8 2 0 0 2 2 1 0 DNA polymerase III subunits gamma and tau domain III Mg_chelatase PF01078.21 RKP00215.1 - 0.016 14.6 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 RKP00215.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKP00215.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 RKP00215.1 - 0.033 13.8 0.3 4.5 6.9 0.0 3.0 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 RKP00215.1 - 0.037 13.3 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 RKP00215.1 - 0.047 13.9 0.1 0.19 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain IPT PF01745.16 RKP00215.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase RNA_helicase PF00910.22 RKP00215.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DNA_pol3_delta PF06144.13 RKP00215.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 RKP00215.1 - 0.091 13.3 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RKP00215.1 - 0.15 12.6 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAR2 PF05282.11 RKP00216.1 - 7.9e-53 180.1 0.0 1.1e-52 179.6 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein RsdA_SigD_bd PF16751.5 RKP00216.1 - 5 7.5 13.0 0.79 10.0 0.6 3.8 4 0 0 4 4 4 0 Anti-sigma-D factor RsdA to sigma factor binding region Coatomer_WDAD PF04053.14 RKP00217.1 - 7.8e-142 473.4 0.0 3.1e-141 471.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 RKP00217.1 - 3.2e-41 138.5 3.9 1.3e-07 32.2 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00217.1 - 1.7e-10 41.0 1.1 0.36 11.2 0.1 6.8 4 4 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 RKP00217.1 - 0.0001 22.3 0.1 0.76 9.8 0.0 4.4 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 RKP00217.1 - 0.0056 15.4 2.6 0.26 9.9 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 TPR_2 PF07719.17 RKP00217.1 - 0.62 10.3 3.7 0.6 10.4 0.7 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_N_2 PF13409.6 RKP00218.1 - 2.1e-15 56.8 0.0 7.2e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RKP00218.1 - 2.2e-10 40.4 0.7 5.4e-10 39.1 0.7 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RKP00218.1 - 3.4e-07 30.4 0.0 7.7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RKP00218.1 - 4.3e-05 23.6 0.0 0.0001 22.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RKP00218.1 - 0.00024 21.5 0.0 0.018 15.5 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 RKP00218.1 - 0.0018 18.0 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Y_phosphatase2 PF03162.13 RKP00219.1 - 1.9e-37 128.4 0.0 2.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKP00219.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 RKP00219.1 - 0.057 13.5 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) DHHC PF01529.20 RKP00220.1 - 1.4e-21 77.0 4.6 2.4e-21 76.2 4.6 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase MTCP1 PF08991.10 RKP00220.1 - 7.5e-11 42.1 8.3 7.5e-11 42.1 8.3 2.1 3 0 0 3 3 3 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 RKP00220.1 - 0.0092 16.1 6.1 0.019 15.1 6.1 1.5 1 0 0 1 1 1 1 CHCH domain Wzy_C PF04932.15 RKP00220.1 - 0.63 9.7 3.1 5.3 6.6 2.3 2.1 2 0 0 2 2 2 0 O-Antigen ligase zf-AN1 PF01428.16 RKP00222.1 - 6.5e-12 45.4 6.6 1e-11 44.8 6.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DPPIV_N PF00930.21 RKP00223.1 - 4.1e-74 249.5 0.0 5.4e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 RKP00223.1 - 2.5e-50 170.9 0.5 4.3e-50 170.1 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 RKP00223.1 - 3.5e-10 39.9 2.1 5.8e-08 32.6 0.7 2.6 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 RKP00223.1 - 2e-07 31.8 1.8 2e-07 31.8 1.8 2.9 2 2 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RKP00223.1 - 1e-06 28.2 0.2 0.00054 19.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKP00223.1 - 1.5e-05 24.8 0.1 2.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 RKP00223.1 - 0.00038 20.1 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 RKP00223.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 RKP00223.1 - 0.002 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 RKP00223.1 - 0.048 13.0 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Secretory lipase Cyclin_N PF00134.23 RKP00224.1 - 1.1e-10 41.3 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RKP00224.1 - 1.3e-05 25.6 0.0 1.5e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin E1-E2_ATPase PF00122.20 RKP00225.1 - 1e-30 106.6 0.2 8.6e-30 103.6 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 RKP00225.1 - 9e-16 58.1 0.8 1.4e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.26 RKP00225.1 - 1.7e-11 44.8 0.1 0.00036 20.9 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKP00225.1 - 4.8e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 RKP00225.1 - 6.6e-05 22.7 4.4 6.6e-05 22.7 4.4 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 RKP00225.1 - 0.038 13.7 0.0 5.7 6.6 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP00225.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Snf7 PF03357.21 RKP00226.1 - 3.1e-11 43.2 19.6 3.1e-11 43.2 19.6 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 RKP00226.1 - 0.00014 21.8 6.2 0.00021 21.2 6.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 RKP00226.1 - 0.0024 17.6 1.2 0.0029 17.3 0.2 1.6 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Big_2 PF02368.18 RKP00226.1 - 0.12 12.3 2.6 0.1 12.5 0.5 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) DUF5601 PF18151.1 RKP00226.1 - 0.48 10.8 3.6 1.3 9.3 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) YlqD PF11068.8 RKP00226.1 - 5.6 7.4 18.0 2.5 8.5 2.1 2.5 2 1 1 3 3 3 0 YlqD protein GST_N_4 PF17172.4 RKP00227.1 - 3.4e-06 27.7 0.2 0.038 14.7 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RKP00227.1 - 4.4e-06 26.4 0.1 1.3e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 RKP00227.1 - 0.015 15.6 0.0 0.05 13.9 0.0 1.9 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Frag1 PF10277.9 RKP00228.1 - 1.5e-31 109.6 6.7 2e-31 109.2 6.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4079 PF13301.6 RKP00228.1 - 0.00046 20.4 0.9 0.0015 18.6 0.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) ECSCR PF15820.5 RKP00228.1 - 0.043 13.6 0.2 0.2 11.5 0.0 2.1 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator HKR_ArcB_TM PF18415.1 RKP00228.1 - 0.098 13.5 0.4 0.098 13.5 0.4 2.3 3 1 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain DUF4064 PF13273.6 RKP00228.1 - 0.27 11.5 9.2 1.7 9.0 3.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1345 PF07077.11 RKP00228.1 - 0.37 10.5 4.9 6.3 6.5 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1345) DHHC PF01529.20 RKP00228.1 - 2.3 8.3 5.7 10 6.2 0.7 2.7 2 1 0 2 2 2 0 DHHC palmitoyltransferase 7tm_1 PF00001.21 RKP00228.1 - 5.4 6.3 7.4 3.6 6.8 3.9 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) MIG-14_Wnt-bd PF06664.12 RKP00228.1 - 6.9 5.8 9.4 5.5 6.1 1.4 2.2 1 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion AMPK1_CBM PF16561.5 RKP00229.1 - 8.7e-30 102.8 0.1 1.3e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 RKP00229.1 - 5.3e-21 74.7 1.6 1.6e-20 73.1 1.6 1.9 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 RKP00229.1 - 0.0076 16.8 0.1 0.014 16.0 0.1 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) EMP70 PF02990.16 RKP00230.1 - 0.092 11.4 4.7 0.099 11.3 4.7 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 UPF0052 PF01933.18 RKP00232.1 - 1.4e-42 146.0 0.0 1.7e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 START PF01852.19 RKP00234.1 - 0.0001 21.8 3.1 0.051 13.0 0.2 2.6 3 0 0 3 3 3 2 START domain Abhydrolase_1 PF00561.20 RKP00236.1 - 6.8e-10 39.0 0.1 5.3e-08 32.8 0.0 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKP00236.1 - 8.1e-05 22.0 0.0 0.00077 18.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 RKP00236.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.16 RKP00236.1 - 0.047 13.3 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.16 RKP00236.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PPR PF01535.20 RKP00237.1 - 1.9e-13 49.6 0.0 0.0029 17.7 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_2 PF13041.6 RKP00237.1 - 4.1e-13 49.3 0.0 5.7e-08 32.8 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 RKP00237.1 - 7.2e-12 45.2 0.0 2e-06 27.8 0.0 3.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 RKP00237.1 - 1e-08 34.7 0.0 0.051 13.3 0.0 4.0 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 RKP00237.1 - 0.081 12.3 11.3 0.085 12.2 0.2 4.5 4 1 1 5 5 5 0 Pentacotripeptide-repeat region of PRORP Fig1 PF12351.8 RKP00238.1 - 3.4 7.6 7.2 0.32 10.9 2.1 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 polyprenyl_synt PF00348.17 RKP00239.1 - 1.4e-87 293.0 0.5 1.4e-87 293.0 0.5 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase Glyco_tranf_2_3 PF13641.6 RKP00240.1 - 0.0047 16.8 0.1 0.0061 16.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RKP00240.1 - 0.0062 16.4 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.25 RKP00241.1 - 4e-61 206.7 0.0 5.8e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00241.1 - 5.5e-33 114.3 0.0 1.3e-32 113.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00241.1 - 0.049 12.9 0.2 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 RKP00241.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RCC1 PF00415.18 RKP00242.1 - 4.6e-21 75.2 4.7 8.6e-07 29.5 0.0 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKP00242.1 - 2.9e-06 26.9 0.4 2.9e-06 26.9 0.4 5.2 5 1 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat SPX PF03105.19 RKP00242.1 - 8.3 6.2 9.2 12 5.6 9.2 1.2 1 0 0 1 1 1 0 SPX domain Guanylate_cyc_2 PF09778.9 RKP00245.1 - 1.2e-49 168.6 0.0 1.3e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Guanylylate cyclase WD40 PF00400.32 RKP00246.1 - 1e-09 38.8 9.7 0.0039 18.0 0.1 6.9 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00246.1 - 4.3e-09 36.5 0.0 0.36 11.2 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain UCH PF00443.29 RKP00247.1 - 7.1e-32 110.9 0.0 1.2e-31 110.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP00247.1 - 4.3e-07 29.8 0.0 0.0083 15.8 0.0 3.8 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 RKP00248.1 - 3.7e-07 30.0 9.1 0.0024 17.8 0.0 3.8 2 1 0 2 2 2 2 Mitochondrial carrier protein Pkinase PF00069.25 RKP00249.1 - 1.4e-51 175.4 0.0 1.7e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00249.1 - 3.5e-30 105.2 0.0 4.8e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP00249.1 - 0.00019 20.8 0.3 0.00026 20.4 0.3 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP00249.1 - 0.0016 17.4 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKP00249.1 - 0.0096 15.9 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKP00249.1 - 0.045 13.3 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 RKP00249.1 - 0.16 11.2 0.0 0.89 8.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like HIT PF01230.23 RKP00250.1 - 1.7e-22 80.0 0.7 2.5e-22 79.5 0.7 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RKP00250.1 - 3.6e-08 33.9 0.1 4.7e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 RKP00250.1 - 0.0034 17.1 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain Mob_Pre PF01076.19 RKP00250.1 - 0.011 15.6 0.2 0.017 15.0 0.1 1.3 1 1 0 1 1 1 0 Plasmid recombination enzyme WLM PF08325.10 RKP00251.1 - 1.4e-45 155.8 0.0 1.5e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 RKP00251.1 - 0.0066 16.5 0.2 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 Hydrophobin PF01185.18 RKP00252.1 - 3.5e-07 30.8 11.5 5e-07 30.3 11.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Kelch_4 PF13418.6 RKP00253.1 - 3e-13 49.5 5.1 0.00023 21.1 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 RKP00253.1 - 1.4e-08 34.5 0.4 0.069 13.2 0.0 6.7 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 RKP00253.1 - 1.8e-07 31.2 28.3 0.00043 20.5 0.0 5.6 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RKP00253.1 - 1e-05 25.6 0.6 0.38 11.1 0.0 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 RKP00253.1 - 0.00085 18.9 6.5 0.98 9.1 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 RKP00253.1 - 0.029 14.4 0.4 5.5 7.1 0.0 3.9 4 0 0 4 4 4 0 Kelch motif Adaptin_N PF01602.20 RKP00254.1 - 3.5e-86 289.8 0.4 5e-86 289.3 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 RKP00254.1 - 7.9e-57 190.8 0.0 1.9e-56 189.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 RKP00254.1 - 5e-55 185.3 0.1 9.8e-55 184.3 0.1 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 RKP00254.1 - 8.5e-09 35.7 0.7 4.4e-07 30.1 0.2 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP00254.1 - 2.3e-06 27.9 2.4 0.00041 20.7 0.0 4.4 3 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 RKP00254.1 - 4e-05 23.5 1.0 0.058 13.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 RKP00254.1 - 0.0028 17.8 0.0 0.055 13.6 0.0 2.7 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform tRNA-synt_1b PF00579.25 RKP00254.1 - 0.12 11.7 0.2 2.4 7.4 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Arm PF00514.23 RKP00254.1 - 6 7.1 6.7 49 4.2 0.0 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat INSIG PF07281.12 RKP00255.1 - 2.3e-18 66.7 7.0 1.4e-17 64.1 7.0 1.9 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) RICTOR_N PF14664.6 RKP00256.1 - 7.5e-74 249.0 1.0 4.5e-73 246.4 1.2 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 RKP00256.1 - 3.8e-30 103.7 0.1 3.5e-28 97.4 0.0 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 RKP00256.1 - 5.3e-30 104.0 0.1 1.4e-27 96.2 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 RKP00256.1 - 3.7e-25 87.9 3.1 4.6e-22 78.0 0.2 4.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 RKP00256.1 - 6.2e-06 26.0 10.4 0.0081 16.3 0.2 5.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 RKP00256.1 - 1.9e-05 24.9 14.5 0.091 13.2 0.1 6.2 4 2 0 5 5 5 2 HEAT repeats Arm PF00514.23 RKP00256.1 - 0.0002 21.3 5.3 1.3 9.1 0.1 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 RKP00256.1 - 0.00037 20.1 0.1 0.03 13.9 0.1 2.5 2 0 0 2 2 2 1 CLASP N terminal Nipped-B_C PF12830.7 RKP00256.1 - 0.048 13.6 6.3 4.9 7.1 0.1 4.2 4 1 1 5 5 5 0 Sister chromatid cohesion C-terminus Siva PF05458.12 RKP00257.1 - 0.2 11.3 22.6 0.24 11.1 20.0 2.2 2 1 0 2 2 2 0 Cd27 binding protein (Siva) DNA_pol_B PF00136.21 RKP00258.1 - 4.9e-145 483.8 0.0 6.5e-145 483.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RKP00258.1 - 1.6e-70 237.9 0.0 3.1e-70 237.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 RKP00258.1 - 8.7e-19 67.8 8.2 1.9e-18 66.7 8.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 RKP00258.1 - 0.003 16.5 0.1 0.0063 15.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 RKP00258.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 RKP00258.1 - 0.1 12.6 0.3 0.58 10.1 0.3 2.1 1 1 0 1 1 1 0 RNase_H superfamily Prok-RING_1 PF14446.6 RKP00258.1 - 0.78 9.7 9.3 0.22 11.5 2.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 RKP00258.1 - 1.8 8.7 7.0 5.5 7.1 7.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon DUF2034 PF10356.9 RKP00259.1 - 3.2e-15 56.0 0.0 1.6e-08 34.2 0.1 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 RKP00259.1 - 7.7e-08 32.4 0.0 3.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease Mrr_cat_2 PF13156.6 RKP00259.1 - 0.22 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease ApoO PF09769.9 RKP00260.1 - 0.0056 16.6 0.2 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 Apolipoprotein O Pkinase PF00069.25 RKP00261.1 - 4.4e-64 216.4 0.0 5e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00261.1 - 8.3e-31 107.2 0.0 9.8e-31 107.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00261.1 - 0.00032 20.1 0.2 0.0017 17.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKP00261.1 - 0.0022 17.0 0.1 1.3 7.9 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 RKP00261.1 - 0.0087 15.4 0.1 0.048 13.0 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP00261.1 - 0.12 12.3 0.0 0.56 10.1 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family PPTA PF01239.22 RKP00262.1 - 2.3e-37 125.6 11.2 2.5e-11 42.9 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Thiolase_N PF00108.23 RKP00263.1 - 2.5e-74 250.0 1.3 4.2e-74 249.2 1.3 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKP00263.1 - 4.3e-45 152.3 0.6 2.7e-44 149.8 0.3 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RKP00263.1 - 0.041 13.4 1.1 0.41 10.2 0.8 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RKP00263.1 - 0.099 12.5 1.0 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CAF1C_H4-bd PF12265.8 RKP00264.1 - 2.2e-16 59.9 0.0 1.3e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 RKP00264.1 - 4.2e-12 46.4 15.8 1.5e-06 28.8 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat zf-RING_2 PF13639.6 RKP00265.1 - 2e-11 44.0 8.4 4e-11 43.0 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RKP00265.1 - 2.7e-11 43.0 1.3 6.2e-11 41.9 1.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RKP00265.1 - 2.5e-08 33.6 9.0 5.3e-08 32.6 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP00265.1 - 6.1e-07 29.2 2.3 1.1e-06 28.4 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKP00265.1 - 0.00015 21.6 4.5 0.00025 20.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP00265.1 - 0.00019 21.4 5.0 0.00028 20.8 1.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RKP00265.1 - 0.00038 20.4 6.4 0.00068 19.5 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 RKP00265.1 - 0.0016 18.7 11.2 0.0067 16.7 11.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 RKP00265.1 - 0.011 15.6 3.8 0.023 14.6 3.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MaAIMP_sms PF16951.5 RKP00265.1 - 0.1 12.3 0.1 0.87 9.4 0.2 2.4 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit FANCL_C PF11793.8 RKP00265.1 - 0.27 11.4 2.2 0.76 10.0 2.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 RKP00265.1 - 0.3 11.1 7.2 0.75 9.9 7.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 RKP00265.1 - 1 9.6 4.7 1.8 8.8 3.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 RKP00265.1 - 1.1 9.2 6.4 2.2 8.2 6.4 1.5 1 0 0 1 1 1 0 PHD-finger AAA_6 PF12774.7 RKP00267.1 - 6.3e-157 521.7 0.1 3.6e-156 519.2 0.0 2.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RKP00267.1 - 1.1e-154 516.2 8.7 1.1e-154 516.2 8.7 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RKP00267.1 - 3.7e-122 408.3 2.3 3.7e-122 408.3 2.3 4.5 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RKP00267.1 - 2.4e-95 318.8 0.0 7.7e-95 317.1 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKP00267.1 - 1.8e-81 272.4 0.2 1.8e-81 272.4 0.2 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 RKP00267.1 - 7.3e-76 255.3 2.5 1.6e-75 254.2 0.1 3.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RKP00267.1 - 3.7e-74 248.2 0.6 5.8e-68 228.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 RKP00267.1 - 2e-52 178.4 18.2 1.1e-51 176.0 11.5 2.6 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RKP00267.1 - 4.5e-44 150.1 0.0 1.1e-43 148.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKP00267.1 - 9.1e-44 148.4 0.0 2.7e-42 143.6 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKP00267.1 - 6.5e-26 91.0 0.0 4.5e-07 30.0 0.0 5.2 5 0 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKP00267.1 - 1.4e-19 70.4 0.0 1e-18 67.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKP00267.1 - 4e-15 55.8 0.1 1.4e-14 54.1 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RKP00267.1 - 8.1e-09 35.9 3.1 0.033 14.4 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 RKP00267.1 - 4e-08 33.8 0.0 0.64 10.4 0.0 5.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RKP00267.1 - 5.3e-08 33.5 0.3 0.025 15.1 0.0 6.1 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.6 RKP00267.1 - 0.00014 22.3 13.3 0.27 11.6 0.0 8.3 8 1 1 9 9 7 1 AAA ATPase domain AAA_29 PF13555.6 RKP00267.1 - 0.0016 18.2 0.1 0.24 11.2 0.0 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 RKP00267.1 - 0.0071 16.1 6.3 0.87 9.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 RKP00267.1 - 0.052 13.4 0.1 0.48 10.3 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 RKP00267.1 - 0.078 13.4 2.6 3.9 7.9 0.0 3.6 4 0 0 4 4 2 0 RNA helicase AAA_33 PF13671.6 RKP00267.1 - 0.26 11.4 1.0 39 4.4 0.0 3.6 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 RKP00267.1 - 0.74 10.2 3.7 1.6e+02 2.5 0.3 4.6 4 0 0 4 4 3 0 AAA domain DUF647 PF04884.14 RKP00268.1 - 8e-50 169.7 8.3 4.4e-29 101.8 1.1 2.2 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis RRM_1 PF00076.22 RKP00269.1 - 1.8e-11 43.7 0.0 2.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RKP00269.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nucleoporin_FG2 PF15967.5 RKP00271.1 - 3.9 5.9 11.2 4.6 5.7 11.2 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region zf-MYND PF01753.18 RKP00272.1 - 0.00058 19.9 3.4 0.00058 19.9 3.4 2.3 2 0 0 2 2 2 1 MYND finger SET PF00856.28 RKP00272.1 - 0.0012 19.2 0.0 0.0023 18.4 0.0 1.7 1 1 0 1 1 1 1 SET domain Ran_BP1 PF00638.18 RKP00273.1 - 9.6e-08 32.3 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain SMK-1 PF04802.15 RKP00274.1 - 1.1e-45 155.8 0.0 1.6e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 HEAT PF02985.22 RKP00274.1 - 0.078 13.3 0.4 0.9 10.0 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat Serglycin PF04360.12 RKP00274.1 - 0.33 10.9 5.8 0.13 12.3 2.2 2.0 2 0 0 2 2 2 0 Serglycin BING4CT PF08149.11 RKP00275.1 - 2.2e-33 113.9 0.0 4.1e-32 109.8 0.0 2.7 2 0 0 2 2 2 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 RKP00275.1 - 1.7e-05 25.0 0.0 9.8 6.6 0.0 4.6 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKP00275.1 - 1.9e-05 25.3 0.3 0.0019 19.0 0.1 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 RKP00275.1 - 2.2e-05 23.7 0.0 3.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 RKP00275.1 - 0.064 13.1 0.0 3.8 7.4 0.0 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DEAD PF00270.29 RKP00276.1 - 2.9e-47 160.7 0.0 9.4e-47 159.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP00276.1 - 5.4e-31 107.2 0.0 1.1e-28 99.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP00276.1 - 1.3e-07 31.8 0.0 6.5e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKP00276.1 - 0.00053 19.3 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 RKP00276.1 - 0.00064 18.6 0.0 0.23 10.2 0.0 2.9 3 0 0 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SWI2_SNF2 PF18766.1 RKP00276.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DAHP_synth_2 PF01474.16 RKP00276.1 - 0.054 12.0 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 Class-II DAHP synthetase family TPR_2 PF07719.17 RKP00277.1 - 0.017 15.2 2.1 3.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKP00277.1 - 0.024 14.6 0.1 2.3 8.5 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP00277.1 - 0.05 13.8 0.1 0.4 10.9 0.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 RKP00277.1 - 0.065 13.7 3.6 0.08 13.5 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 RKP00277.1 - 1.5 9.5 24.5 1.1 10.0 4.9 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RIIa PF02197.17 RKP00278.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF898 PF05987.13 RKP00279.1 - 0.041 12.9 3.3 0.11 11.6 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) Shisa PF13908.6 RKP00279.1 - 0.51 10.6 4.3 0.94 9.7 4.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 RKP00279.1 - 3.1 8.1 5.7 7 7.0 5.7 1.5 1 0 0 1 1 1 0 Orf78 (ac78) AAA_16 PF13191.6 RKP00280.1 - 5.7e-05 23.6 3.1 0.00084 19.8 0.1 3.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP00280.1 - 0.18 12.1 0.2 5.1 7.4 0.1 2.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 RKP00280.1 - 0.19 11.2 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 RKP00280.1 - 0.19 11.6 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Alpha-amylase_N PF02903.14 RKP00281.1 - 4.7 7.4 6.8 46 4.2 1.3 3.5 3 1 1 4 4 4 0 Alpha amylase, N-terminal ig-like domain IQ PF00612.27 RKP00282.1 - 8e-06 25.2 2.7 2.7e-05 23.6 2.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3764 PF12594.8 RKP00282.1 - 0.16 12.0 0.5 1.1 9.4 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3764) DUF4407 PF14362.6 RKP00282.1 - 0.66 9.3 39.1 0.046 13.1 18.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LepB_GAP_N PF18172.1 RKP00282.1 - 0.75 9.7 12.6 3.6 7.4 4.4 2.4 1 1 1 2 2 2 0 LepB GAP domain N-terminal subdomain DUF1564 PF07600.11 RKP00282.1 - 1.4 8.5 4.8 0.21 11.3 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) ACR_tran PF00873.19 RKP00282.1 - 8.5 3.9 10.4 11 3.5 10.4 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family EBV-NA1 PF02905.14 RKP00284.1 - 0.0028 17.5 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Epstein Barr virus nuclear antigen-1, DNA-binding domain Mito_carr PF00153.27 RKP00286.1 - 8.2e-38 128.2 0.2 3.5e-15 55.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf_C2H2_ZHX PF18387.1 RKP00286.1 - 0.093 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Prefoldin PF02996.17 RKP00287.1 - 1.4e-22 79.8 0.8 1.9e-22 79.4 0.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF5611 PF18446.1 RKP00287.1 - 0.08 13.8 0.1 0.32 11.9 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5611) Utp12 PF04003.12 RKP00287.1 - 0.15 12.4 0.6 1.6 9.1 0.1 2.1 2 0 0 2 2 2 0 Dip2/Utp12 Family Sec2p PF06428.11 RKP00287.1 - 1.2 9.1 5.2 0.6 10.1 1.4 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Med4 PF10018.9 RKP00288.1 - 1.8e-07 31.0 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1995 PF09353.10 RKP00288.1 - 0.002 18.2 6.5 0.0039 17.2 6.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Sulfate_transp PF00916.20 RKP00289.1 - 2e-52 178.2 25.6 2e-52 178.2 25.6 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RKP00289.1 - 2.3e-06 27.2 0.0 5.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain Pkinase PF00069.25 RKP00290.1 - 2.7e-59 200.7 0.0 3.4e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00290.1 - 1.9e-41 142.1 0.4 4.7e-40 137.5 0.4 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00290.1 - 2.6e-05 23.7 0.0 0.00065 19.1 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKP00290.1 - 0.0076 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 RKP00290.1 - 0.052 12.6 0.1 0.08 12.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 RKP00290.1 - 0.064 12.8 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.19 RKP00290.1 - 1.5 9.4 6.7 4.9 7.8 6.1 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cyclin_N PF00134.23 RKP00294.1 - 0.0059 16.4 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RKP00294.1 - 0.2 12.0 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 Cyclin AF-4 PF05110.13 RKP00295.1 - 1.9 6.5 11.6 0.65 8.0 6.9 1.9 2 0 0 2 2 2 0 AF-4 proto-oncoprotein TIP120 PF08623.10 RKP00297.1 - 1.4e-42 145.3 0.3 1.6e-41 141.9 0.1 3.0 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 RKP00297.1 - 1.4e-09 37.4 38.7 0.041 14.1 1.1 11.8 12 0 0 12 12 11 3 HEAT repeat Cnd1 PF12717.7 RKP00297.1 - 8e-05 22.7 9.5 0.018 15.1 0.3 4.8 7 0 0 7 7 6 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 RKP00297.1 - 0.0012 18.9 3.3 0.12 12.5 0.1 4.3 4 0 0 4 4 4 1 Parkin co-regulated protein TAF6_C PF07571.13 RKP00297.1 - 0.0056 17.0 2.8 9.3 6.7 0.0 4.9 4 1 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain BUD22 PF09073.10 RKP00297.1 - 0.014 14.7 7.3 0.024 14.0 7.3 1.3 1 0 0 1 1 1 0 BUD22 MMS19_C PF12460.8 RKP00297.1 - 0.017 14.2 16.9 0.11 11.6 0.0 5.1 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 RKP00297.1 - 0.018 15.1 0.0 0.61 10.1 0.0 3.3 2 1 0 2 2 2 0 Exportin 1-like protein DRIM PF07539.12 RKP00297.1 - 0.027 12.8 4.5 5.2 5.2 0.0 4.4 5 0 0 5 5 5 0 Down-regulated in metastasis RACo_linker PF17650.1 RKP00297.1 - 0.033 14.0 0.9 0.97 9.3 0.1 3.3 2 0 0 2 2 2 0 RACo linker region RTP1_C1 PF10363.9 RKP00297.1 - 0.041 14.1 3.9 1.1e+02 3.0 0.1 6.2 6 1 1 7 7 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 RKP00297.1 - 0.38 9.2 7.2 13 4.2 0.0 4.6 5 0 0 5 5 5 0 Adaptin N terminal region DUF3384 PF11864.8 RKP00297.1 - 0.42 9.4 2.9 8.7 5.1 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) DUF3437 PF11919.8 RKP00297.1 - 0.53 10.2 7.1 1.7 8.6 0.0 4.5 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) Sigma70_ner PF04546.13 RKP00297.1 - 0.67 9.8 16.5 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region GCIP PF13324.6 RKP00297.1 - 0.78 9.3 10.3 2 7.9 4.5 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting RIX1 PF08167.12 RKP00297.1 - 1.4 8.7 11.2 39 3.9 0.2 5.5 6 1 0 6 6 5 0 rRNA processing/ribosome biogenesis TFCD_C PF12612.8 RKP00297.1 - 1.7 8.5 5.6 8.4 6.2 0.1 4.3 6 0 0 6 6 6 0 Tubulin folding cofactor D C terminal TFIIF_alpha PF05793.12 RKP00297.1 - 2 6.9 10.5 0.27 9.8 0.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HEAT_EZ PF13513.6 RKP00297.1 - 2 9.0 41.3 0.56 10.8 0.1 11.8 13 1 1 14 14 12 0 HEAT-like repeat Proteasom_PSMB PF10508.9 RKP00297.1 - 5.7 5.3 5.5 2.3 6.6 0.5 2.8 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 RKP00297.1 - 7.3 7.1 54.0 0.083 13.3 0.8 10.8 8 4 4 12 12 12 0 HEAT repeats PAP2 PF01569.21 RKP00298.1 - 1.7e-24 86.2 5.7 3.2e-24 85.2 5.7 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 RKP00298.1 - 1.6 8.4 10.0 8.7 6.0 10.0 1.9 1 1 0 1 1 1 0 PAP2 superfamily UQ_con PF00179.26 RKP00299.1 - 9.5e-49 164.6 0.0 1.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mob1_phocein PF03637.17 RKP00300.1 - 7e-56 188.9 0.0 8.3e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family AZUL PF16558.5 RKP00300.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF4535 PF15054.6 RKP00301.1 - 7.5e-06 25.6 0.3 3.8e-05 23.3 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4535) Romo1 PF10247.9 RKP00301.1 - 0.006 16.9 0.0 0.0072 16.7 0.0 1.3 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SIS PF01380.22 RKP00302.1 - 8.7e-64 213.2 0.4 2.3e-32 111.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 RKP00302.1 - 3.6e-17 62.8 0.0 8.5e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RKP00302.1 - 1.2e-12 47.8 0.0 3.3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RKP00302.1 - 0.0001 21.3 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RKP00302.1 - 0.0069 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 SIS domain GATase_2 PF00310.21 RKP00302.1 - 0.082 11.6 0.0 0.38 9.4 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Ysc84 PF04366.12 RKP00303.1 - 2.1e-43 147.1 0.1 3.6e-43 146.4 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 RKP00303.1 - 1.9e-14 53.0 0.0 4.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP00303.1 - 3.2e-10 39.7 0.0 5.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP00303.1 - 3.6e-09 36.2 0.0 8.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UQ_con PF00179.26 RKP00304.1 - 1.3e-47 160.9 0.0 1.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKP00304.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RKP00304.1 - 0.027 14.7 1.5 0.033 14.5 1.5 1.5 1 1 0 1 1 1 0 RWD domain CytochromB561_N PF09786.9 RKP00305.1 - 8.8e-17 61.3 3.1 1.9e-05 23.9 0.0 4.7 4 1 0 4 4 4 3 Cytochrome B561, N terminal Gti1_Pac2 PF09729.9 RKP00307.1 - 2e-47 161.6 0.1 4.6e-38 131.1 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family DUF382 PF04037.13 RKP00308.1 - 5.5e-52 175.2 0.0 7e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 RKP00308.1 - 3.7e-21 74.7 3.7 7.7e-21 73.7 3.7 1.6 1 0 0 1 1 1 1 PSP NTP_transf_2 PF01909.23 RKP00309.1 - 4e-12 46.3 0.0 8.9e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 RKP00309.1 - 0.0009 19.4 0.4 0.0024 18.0 0.4 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 RKP00309.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase NtA PF03146.15 RKP00310.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Agrin NtA domain Aminotran_3 PF00202.21 RKP00312.1 - 1.4e-108 363.2 0.0 1.6e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 RKP00312.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II DUF4200 PF13863.6 RKP00313.1 - 5.9e-25 88.0 22.5 1.8e-22 80.0 13.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 RKP00313.1 - 0.0039 17.1 13.6 0.012 15.6 0.8 3.4 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding CHASE7 PF17151.4 RKP00313.1 - 0.12 11.9 6.9 0.077 12.6 4.5 2.0 1 1 0 1 1 1 0 Periplasmic sensor domain Sigma_reg_C PF13791.6 RKP00313.1 - 0.13 12.5 4.3 0.078 13.2 2.0 1.8 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Spc7 PF08317.11 RKP00313.1 - 0.14 11.0 22.7 0.3 9.9 5.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 RKP00313.1 - 0.35 10.2 14.9 0.037 13.4 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 RKP00313.1 - 0.47 10.6 17.0 0.093 12.9 3.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CRR7 PF12095.8 RKP00313.1 - 0.58 10.6 9.4 1.1 9.8 1.9 3.5 2 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1664 PF07889.12 RKP00313.1 - 0.71 9.9 14.9 1.5 8.8 0.8 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) COG5 PF10392.9 RKP00313.1 - 2.8 8.1 14.3 0.15 12.3 7.4 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 HrpB7 PF09486.10 RKP00313.1 - 9.4 6.6 23.4 0.35 11.2 7.5 2.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Methyltransf_23 PF13489.6 RKP00315.1 - 6.7e-17 61.8 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP00315.1 - 8.9e-17 61.7 0.0 4.1e-16 59.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP00315.1 - 2.3e-14 53.9 0.0 5.6e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKP00315.1 - 3.3e-11 43.7 0.0 6.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKP00315.1 - 4.9e-09 36.1 0.0 7.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKP00315.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 RKP00315.1 - 0.04 14.9 0.0 0.24 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 RKP00315.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB CheR PF01739.18 RKP00315.1 - 0.056 12.9 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.17 RKP00315.1 - 0.15 11.2 0.0 0.48 9.6 0.0 1.8 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family DAD PF02109.16 RKP00316.1 - 7.3e-34 116.4 0.4 9.2e-34 116.0 0.4 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.6 RKP00316.1 - 0.035 14.0 0.4 0.064 13.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) TPR_12 PF13424.6 RKP00317.1 - 8.5e-07 29.2 6.0 0.00072 19.8 0.2 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP00317.1 - 1.1e-05 25.1 3.8 0.042 13.9 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP00317.1 - 2.2e-05 24.0 0.2 0.046 13.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RKP00317.1 - 4.5e-05 23.2 0.2 0.013 15.4 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKP00317.1 - 0.0013 18.7 1.4 0.77 10.0 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat SUIM_assoc PF16619.5 RKP00317.1 - 1 9.5 5.8 6 7.0 5.8 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DNA_pol_E_B PF04042.16 RKP00318.1 - 3.2e-34 118.1 0.1 4e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.7 RKP00318.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CBP4 PF07960.11 RKP00319.1 - 0.00025 20.9 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 CBP4 VPS28 PF03997.12 RKP00320.1 - 2.3e-65 219.9 0.0 2.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Herpes_capsid PF06112.11 RKP00320.1 - 5.6 7.0 11.2 10 6.2 11.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HEAT_2 PF13646.6 RKP00321.1 - 4.6e-09 36.6 9.6 0.00092 19.6 0.3 6.2 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 RKP00321.1 - 1.3e-07 31.3 15.1 0.098 13.0 0.1 6.7 6 0 0 6 6 6 4 HEAT repeat DUF4042 PF13251.6 RKP00321.1 - 3.5 7.3 12.2 3.3 7.4 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) Ribosomal_S3Ae PF01015.18 RKP00322.1 - 2.3e-88 295.0 1.6 2.7e-88 294.8 1.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family WD40 PF00400.32 RKP00323.1 - 1.1e-18 67.2 13.3 0.012 16.4 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 RKP00323.1 - 0.14 10.7 3.4 5.2 5.6 0.0 3.6 2 1 1 5 5 5 0 Nucleoporin Nup120/160 Tic110 PF16940.5 RKP00324.1 - 0.27 9.7 4.0 0.33 9.4 4.0 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter UCR_Fe-S_N PF10399.9 RKP00324.1 - 0.44 9.9 16.3 0.8 9.1 16.3 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ATP-synt_D PF01813.17 RKP00325.1 - 1.5e-73 246.8 1.0 2.2e-73 246.3 1.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF4300 PF14133.6 RKP00325.1 - 0.0069 16.1 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4300) EF-G-binding_N PF07299.11 RKP00325.1 - 0.036 14.6 0.8 0.1 13.1 0.8 1.8 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal NPV_P10 PF05531.12 RKP00325.1 - 0.37 11.3 1.9 25 5.4 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ca_bind_SSO6904 PF18249.1 RKP00325.1 - 7.7 7.0 6.9 28 5.2 0.9 3.3 2 1 1 3 3 3 0 Calcium binding protein SSO6904 Diphthami_syn_2 PF01902.17 RKP00326.1 - 9.1e-35 120.1 0.0 1.8e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 RKP00326.1 - 1e-06 28.8 0.2 5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Endoribonuclease L-PSP Pkinase PF00069.25 RKP00327.1 - 2e-23 83.1 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00327.1 - 8.7e-10 38.3 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP00327.1 - 1.1e-06 27.7 0.0 1.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Myb_DNA-bind_3 PF12776.7 RKP00328.1 - 4e-05 24.5 0.0 5.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 RKP00328.1 - 0.081 11.2 8.7 0.11 10.8 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 RKP00328.1 - 0.092 11.0 11.1 0.12 10.6 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 RKP00328.1 - 0.32 9.4 6.5 0.41 9.0 6.5 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RKP00328.1 - 0.35 10.2 12.3 0.49 9.8 12.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RKP00328.1 - 0.63 9.3 11.3 0.88 8.8 11.3 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 RKP00328.1 - 2.5 6.1 26.6 3.4 5.7 26.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SPX PF03105.19 RKP00328.1 - 9.8 6.0 7.5 13 5.5 7.5 1.2 1 0 0 1 1 1 0 SPX domain Autophagy_act_C PF03987.15 RKP00329.1 - 2.7e-08 34.3 0.0 4.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CAP_N PF01213.19 RKP00329.1 - 0.79 9.1 3.2 1.1 8.6 3.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRMT5 PF05185.16 RKP00330.1 - 1.1e-48 165.3 0.0 1.4e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 RKP00330.1 - 2e-33 115.8 0.1 5e-33 114.4 0.1 1.6 1 1 0 1 1 1 1 PRMT5 oligomerisation domain PNPase_C PF12111.8 RKP00330.1 - 0.1 12.0 3.5 0.32 10.5 0.5 2.5 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal HOASN PF14515.6 RKP00330.1 - 0.13 12.7 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices DUF5404 PF17397.2 RKP00331.1 - 0.047 13.8 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5404) RIO1 PF01163.22 RKP00332.1 - 2.4e-46 157.7 0.0 3.4e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 RKP00332.1 - 3.5e-32 110.4 0.3 7.6e-32 109.4 0.3 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 RKP00332.1 - 3.2e-09 37.0 1.9 0.00054 20.0 0.8 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RKP00332.1 - 4.5e-07 29.4 0.1 0.0064 15.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 RKP00333.1 - 0.016 16.1 0.0 44 5.2 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat TMEM154 PF15102.6 RKP00333.1 - 2.7 7.9 4.7 16 5.4 0.9 2.4 2 0 0 2 2 2 0 TMEM154 protein family Methyltransf_34 PF11312.8 RKP00334.1 - 1.1e-33 116.8 0.0 4.1e-33 114.9 0.0 1.9 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase Lipase_3 PF01764.25 RKP00335.1 - 8.7e-17 61.3 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 RKP00335.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) CaATP_NAI PF12515.8 RKP00335.1 - 0.084 12.5 0.1 0.4 10.3 0.1 2.2 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain Chlorophyllase2 PF12740.7 RKP00335.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme WD40 PF00400.32 RKP00336.1 - 3.6e-07 30.8 0.8 0.00034 21.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00336.1 - 0.0071 16.6 0.1 15 5.9 0.0 4.6 4 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 RKP00336.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain ASH PF15780.5 RKP00338.1 - 1.3e-60 201.7 49.5 0.001 19.2 0.0 29.5 31 2 2 33 33 32 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RKP00338.1 - 9.4e-24 83.5 9.2 0.0016 18.5 0.0 12.9 12 0 0 12 12 12 6 Flagellar-associated PapD-like DUF1573 PF07610.11 RKP00338.1 - 1e-20 73.5 0.0 1.1 9.4 0.0 16.6 21 0 0 21 21 21 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 RKP00338.1 - 3.3e-18 65.5 0.0 1.2 9.0 0.0 14.5 17 0 0 17 17 17 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RKP00338.1 - 2.8e-12 46.7 18.0 0.22 11.8 0.0 14.5 16 0 0 16 16 16 2 Transmembrane protein 131-like MYCBPAP PF14646.6 RKP00338.1 - 2e-08 33.6 1.9 4.5 6.1 0.0 7.7 8 0 0 8 8 8 2 MYCBP-associated protein family Ig_GlcNase PF18368.1 RKP00338.1 - 5.5e-06 26.5 0.9 21 5.3 0.0 7.5 7 0 0 7 7 7 0 Exo-beta-D-glucosaminidase Ig-fold domain fn3_5 PF06280.12 RKP00338.1 - 0.00082 20.0 22.7 19 6.0 0.0 11.7 15 1 0 15 15 13 0 Fn3-like domain DUF5001 PF16392.5 RKP00338.1 - 0.003 17.4 8.4 28 4.7 0.0 9.0 9 1 2 11 11 11 0 Ig-like domain Fn3-like PF14310.6 RKP00338.1 - 0.0043 17.1 3.3 4.9 7.3 0.0 5.5 6 0 0 6 6 5 1 Fibronectin type III-like domain AAA_33 PF13671.6 RKP00338.1 - 0.0055 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain LEA_2 PF03168.13 RKP00338.1 - 0.012 16.1 1.4 1 9.9 0.0 4.4 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF4981 PF16353.5 RKP00338.1 - 0.019 15.4 0.1 6.8 7.3 0.0 5.3 5 0 0 5 5 4 0 Domain of unknown function(DUF4981) AAA_18 PF13238.6 RKP00338.1 - 0.021 15.4 0.0 0.042 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 RKP00340.1 - 1.1e-13 50.2 29.6 0.0054 16.8 0.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 RKP00340.1 - 1.4e-12 46.8 10.4 0.0026 17.5 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKP00340.1 - 1.3e-08 34.4 1.0 0.0013 18.8 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKP00340.1 - 1e-06 28.3 1.3 0.00038 20.1 0.0 3.0 1 1 1 2 2 2 2 TPR repeat ANAPC3 PF12895.7 RKP00340.1 - 3.1e-06 27.3 0.2 3.1e-06 27.3 0.2 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 RKP00340.1 - 8.3e-06 26.4 11.2 8.3e-06 26.4 11.2 12.3 15 1 1 16 16 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKP00340.1 - 0.00012 22.3 1.7 0.00012 22.3 1.7 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 RKP00340.1 - 0.00033 19.9 13.2 0.0026 17.0 1.8 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 RKP00340.1 - 0.0013 18.7 2.0 0.0083 16.1 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP00340.1 - 0.0014 18.5 9.1 0.021 14.8 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKP00340.1 - 0.0025 18.5 3.1 0.0025 18.5 3.1 13.4 15 1 1 16 16 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 RKP00340.1 - 0.075 13.5 40.7 0.077 13.5 6.3 8.1 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKP00340.1 - 0.18 12.5 0.1 0.18 12.5 0.1 8.4 11 0 0 11 11 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKP00340.1 - 0.32 11.5 7.9 72 4.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Disulph_isomer PF06491.11 RKP00340.1 - 1.9 8.6 3.6 5.7 7.0 3.6 1.8 1 0 0 1 1 1 0 Disulphide isomerase Glyco_transf_22 PF03901.17 RKP00341.1 - 2.5e-68 231.3 0.0 3.2e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family WD40 PF00400.32 RKP00342.1 - 4e-17 62.3 23.4 0.00066 20.4 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00342.1 - 3.3e-15 56.1 2.2 0.00031 21.0 0.1 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP00342.1 - 5.1e-05 22.4 1.5 0.019 13.9 0.5 3.8 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKP00342.1 - 0.0031 17.4 0.1 0.15 11.9 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IFT20 PF14931.6 RKP00344.1 - 9e-15 54.9 0.2 8.8e-14 51.7 0.2 1.9 1 1 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF349 PF03993.12 RKP00344.1 - 0.61 10.4 4.9 1.1 9.6 1.2 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Herpes_gE PF02480.16 RKP00345.1 - 0.0027 16.5 0.0 0.0044 15.8 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 RKP00345.1 - 0.0033 18.3 0.0 0.0085 17.0 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 RKP00345.1 - 0.0047 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Cadherin_C_2 PF16492.5 RKP00345.1 - 0.028 15.1 0.0 0.065 14.0 0.0 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal CD34_antigen PF06365.12 RKP00345.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Prominin PF05478.11 RKP00345.1 - 0.22 9.5 4.3 0.3 9.0 4.3 1.0 1 0 0 1 1 1 0 Prominin WBP-1 PF11669.8 RKP00345.1 - 0.22 12.2 0.3 0.22 12.2 0.3 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 Tweety PF04906.13 RKP00345.1 - 0.29 9.8 0.7 0.4 9.3 0.7 1.1 1 0 0 1 1 1 0 Tweety Rhabdo_glycop PF00974.18 RKP00345.1 - 0.68 8.3 1.2 0.95 7.8 1.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein ATP-synt_C PF00137.21 RKP00348.1 - 6.1e-34 116.2 34.2 4.4e-22 78.2 13.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C WD40 PF00400.32 RKP00349.1 - 1.7e-07 31.8 9.3 8.8e-07 29.5 0.8 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00349.1 - 2.6e-07 30.8 0.1 0.025 14.9 0.0 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DZR PF12773.7 RKP00349.1 - 1 9.5 4.5 10 6.2 0.2 2.6 2 0 0 2 2 2 0 Double zinc ribbon RNA_pol_I_A49 PF06870.12 RKP00350.1 - 1e-57 195.8 0.0 1.5e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SWI-SNF_Ssr4 PF08549.10 RKP00350.1 - 0.005 15.5 0.0 0.005 15.5 0.0 2.2 3 0 0 3 3 3 1 Fungal domain of unknown function (DUF1750) Actin PF00022.19 RKP00351.1 - 8.7e-124 413.2 0.0 1e-123 413.0 0.0 1.0 1 0 0 1 1 1 1 Actin Metallothio_Euk PF12749.7 RKP00351.1 - 0.071 13.3 0.6 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic metallothionein SET PF00856.28 RKP00352.1 - 2.5e-19 70.3 0.0 4e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 SET domain AWS PF17907.1 RKP00352.1 - 8.3e-05 22.5 8.3 8.3e-05 22.5 8.3 2.8 3 0 0 3 3 3 1 AWS domain SNF2_N PF00176.23 RKP00353.1 - 5.7e-56 189.7 0.0 9.6e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKP00353.1 - 8.2e-15 55.1 0.0 2.2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP00353.1 - 2.7e-08 34.0 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 RKP00353.1 - 5.5e-07 29.9 0.1 1.6e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 Rad54 N terminal HDA2-3 PF11496.8 RKP00353.1 - 0.00045 19.5 0.0 0.0016 17.6 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Dymeclin PF09742.9 RKP00354.1 - 3.4e-05 22.5 0.0 0.029 12.8 0.0 2.6 3 0 0 3 3 3 2 Dyggve-Melchior-Clausen syndrome protein Pro_isomerase PF00160.21 RKP00356.1 - 1.5e-21 77.3 0.0 1.7e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MORN PF02493.20 RKP00357.1 - 4.7e-25 85.9 44.0 4.5e-05 23.1 1.2 7.2 7 0 0 7 7 7 7 MORN repeat YchF-GTPase_C PF06071.13 RKP00358.1 - 8.3e-39 131.7 0.1 8.3e-39 131.7 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 RKP00358.1 - 2.5e-21 75.9 0.0 8.7e-21 74.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP00358.1 - 3.3e-07 30.0 0.0 5.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 RKP00358.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 TGS domain Dynamin_N PF00350.23 RKP00358.1 - 0.039 14.0 0.8 1.2 9.2 0.1 2.6 2 1 1 3 3 3 0 Dynamin family MeaB PF03308.16 RKP00358.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RKP00358.1 - 0.11 12.7 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 RKP00358.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 RKP00359.1 - 1.8e-62 211.1 0.0 2.3e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00359.1 - 1e-28 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKP00359.1 - 1.5e-06 27.4 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP00359.1 - 0.00055 19.4 0.1 0.00095 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP00359.1 - 0.023 14.6 0.2 0.056 13.4 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RKP00359.1 - 0.025 14.2 0.1 0.35 10.5 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RKP00359.1 - 0.027 13.2 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase MFS_2 PF13347.6 RKP00360.1 - 1.6e-06 27.0 27.8 1.1e-05 24.2 12.2 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein SecG PF03840.14 RKP00360.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.3 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Fungal_trans PF04082.18 RKP00361.1 - 5.1e-08 32.3 0.5 8e-08 31.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CH PF00307.31 RKP00362.1 - 3.6e-18 65.7 0.3 2.4e-09 37.4 0.0 3.5 4 0 0 4 4 4 2 Calponin homology (CH) domain SHE3 PF17078.5 RKP00362.1 - 0.12 12.1 2.9 0.23 11.2 2.9 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 COG5 PF10392.9 RKP00362.1 - 0.36 11.0 4.2 1.1 9.4 4.2 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlxA PF14282.6 RKP00362.1 - 6.1 6.9 8.7 1.8 8.6 4.3 2.4 2 0 0 2 2 2 0 FlxA-like protein CWC25 PF12542.8 RKP00363.1 - 5.7e-15 56.1 0.0 5.7e-15 56.1 0.0 3.6 5 0 0 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.9 RKP00363.1 - 2.2e-12 46.9 9.5 2.2e-12 46.9 9.5 2.5 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Pkinase PF00069.25 RKP00364.1 - 2.9e-76 256.3 0.0 3.4e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00364.1 - 3.1e-35 121.7 0.0 3.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP00364.1 - 1.4e-09 37.3 0.2 5.7e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 RKP00364.1 - 4.6e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 RKP00364.1 - 0.0051 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP00364.1 - 0.0071 16.3 0.0 0.5 10.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RKP00364.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Inhibitor_I9 PF05922.16 RKP00365.1 - 8.2e-08 32.8 0.0 1.6e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 GYF PF02213.16 RKP00366.1 - 1.4e-05 24.6 0.1 2.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 RKP00366.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 BRCT_2 PF16589.5 RKP00367.1 - 2.3e-14 53.5 0.0 0.015 15.7 0.0 5.5 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 RKP00367.1 - 9.7e-10 38.2 0.0 7.1e-09 35.5 0.0 2.4 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RKP00367.1 - 3.7e-09 36.8 0.0 0.037 14.4 0.0 4.3 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 RKP00367.1 - 1.1e-05 25.6 0.7 2.1 8.7 0.0 4.9 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 RKP00367.1 - 0.00028 20.8 4.9 0.045 13.7 0.0 4.8 6 0 0 6 6 6 1 twin BRCT domain DNA_pol_B PF00136.21 RKP00368.1 - 1.1e-92 311.1 0.0 1.4e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RKP00368.1 - 6.9e-09 35.3 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 RKP00368.1 - 0.036 12.9 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Ras PF00071.22 RKP00369.1 - 1.3e-63 213.5 0.9 1.5e-63 213.3 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP00369.1 - 9.5e-37 125.9 0.2 1.4e-36 125.4 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP00369.1 - 1.5e-16 60.4 0.2 1.7e-16 60.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RKP00369.1 - 5.4e-06 26.4 0.6 0.085 12.8 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 RKP00369.1 - 6.3e-06 25.7 0.2 8.3e-06 25.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKP00369.1 - 1.2e-05 25.3 0.0 2.9e-05 24.1 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 RKP00369.1 - 2.7e-05 23.7 0.1 4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RKP00369.1 - 4.1e-05 23.2 0.6 9.9e-05 22.0 0.3 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 RKP00369.1 - 0.00043 19.7 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein AAA PF00004.29 RKP00369.1 - 0.0021 18.5 0.0 0.032 14.6 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 RKP00369.1 - 0.0078 16.0 0.1 0.15 11.8 0.0 2.2 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 RKP00369.1 - 0.0084 15.6 0.1 0.057 12.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 RKP00369.1 - 0.022 15.2 0.0 0.038 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain LANC_like PF05147.13 RKP00369.1 - 0.028 13.0 0.1 0.053 12.1 0.0 1.4 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein AAA_22 PF13401.6 RKP00369.1 - 0.028 14.7 0.0 0.059 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RKP00369.1 - 0.033 14.2 0.1 0.067 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) rve PF00665.26 RKP00369.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain AAA_29 PF13555.6 RKP00369.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dioxygenase_N PF04444.14 RKP00369.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus AAA_7 PF12775.7 RKP00369.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 RKP00369.1 - 0.11 13.1 0.1 0.19 12.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter CDC45 PF02724.14 RKP00370.1 - 0.046 12.0 3.4 0.072 11.4 3.4 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 RKP00370.1 - 1.4 7.4 6.8 2.2 6.8 6.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.13 RKP00370.1 - 1.9 7.0 5.6 2.7 6.5 5.6 1.2 1 0 0 1 1 1 0 Utp14 protein YL1 PF05764.13 RKP00370.1 - 4.3 7.4 12.7 0.084 13.0 3.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.12 RKP00370.1 - 6.5 4.8 8.2 8.7 4.4 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 RKP00370.1 - 7.3 6.2 5.6 17 5.1 5.6 1.5 1 0 0 1 1 1 0 FAM176 family GATA PF00320.27 RKP00371.1 - 7.7e-11 41.4 0.5 1.7e-10 40.3 0.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Pkinase PF00069.25 RKP00372.1 - 8.3e-60 202.4 0.0 9.4e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00372.1 - 6.4e-37 127.2 0.0 7.4e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00372.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP00372.1 - 0.0073 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKP00372.1 - 0.033 14.1 0.7 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 RKP00372.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 RKP00372.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.27 RKP00373.1 - 3e-65 216.2 1.2 7.4e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHHC PF01529.20 RKP00374.1 - 2.6e-32 111.7 11.5 2.6e-32 111.7 11.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Trep_Strep PF09605.10 RKP00374.1 - 0.32 11.0 11.5 0.12 12.4 3.3 2.8 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2244 PF10003.9 RKP00374.1 - 0.51 10.0 2.9 0.67 9.6 0.3 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3789 PF12664.7 RKP00374.1 - 2.5 7.9 6.9 4.6 7.0 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) Xpo1 PF08389.12 RKP00375.1 - 5.2e-14 52.6 0.0 1.8e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 RKP00375.1 - 0.08 12.9 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Importin-beta N-terminal domain Sugar_tr PF00083.24 RKP00376.1 - 4e-90 302.8 21.7 1.6e-87 294.2 21.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RKP00376.1 - 2.1e-27 96.0 36.0 3e-26 92.2 27.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RKP00376.1 - 0.00021 19.8 5.2 0.00046 18.7 5.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2830 PF11125.8 RKP00376.1 - 0.15 12.0 0.8 0.37 10.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) Pkinase PF00069.25 RKP00377.1 - 1.1e-44 152.8 0.0 1.3e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00377.1 - 3.5e-24 85.5 0.0 4.3e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00377.1 - 0.0018 17.7 0.0 0.0036 16.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RKP00377.1 - 0.0031 17.5 1.8 0.01 15.8 1.5 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKP00377.1 - 0.035 12.9 0.0 0.06 12.1 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase WD40 PF00400.32 RKP00378.1 - 4.7e-28 96.8 8.8 4.6e-06 27.3 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 RKP00378.1 - 2.5e-10 39.7 0.9 0.017 13.8 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RKP00378.1 - 0.009 14.8 0.0 5.2 5.7 0.0 3.1 1 1 0 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 RKP00378.1 - 0.015 15.6 0.1 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RKP00378.1 - 0.018 15.5 0.7 3.5 8.2 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain Hira PF07569.11 RKP00378.1 - 0.051 13.3 0.0 2.4 7.8 0.0 2.5 2 1 0 2 2 2 0 TUP1-like enhancer of split JHD PF17811.1 RKP00379.1 - 5.4e-07 30.1 0.1 8.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 RKP00379.1 - 3.9e-06 27.3 0.1 0.00016 22.1 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RKP00379.1 - 1.7e-05 24.7 0.0 6.5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cerato-platanin PF07249.12 RKP00381.1 - 0.00029 20.9 0.3 0.001 19.2 0.2 1.9 1 1 1 2 2 2 1 Cerato-platanin LEA_2 PF03168.13 RKP00382.1 - 0.046 14.2 0.6 1.4 9.5 0.6 2.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein DUF1356 PF07092.12 RKP00382.1 - 0.18 11.1 0.9 1 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Peptidase_M48 PF01435.18 RKP00383.1 - 5e-36 124.3 0.1 8.9e-36 123.5 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M48 RCC1 PF00415.18 RKP00387.1 - 4.2e-09 36.9 0.8 0.0092 16.6 0.0 4.2 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKP00387.1 - 0.61 9.9 20.0 0.27 11.1 3.1 4.4 4 1 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat DUF4633 PF15464.6 RKP00388.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) F-box PF00646.33 RKP00388.1 - 0.073 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 F-box domain Kinesin PF00225.23 RKP00389.1 - 5.5e-116 387.1 0.0 6.3e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP00389.1 - 2e-23 82.9 0.0 3.2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PCO_ADO PF07847.12 RKP00389.1 - 0.0075 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 PCO_ADO AAA PF00004.29 RKP00389.1 - 0.054 13.9 0.1 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKP00389.1 - 0.06 13.6 0.3 0.23 11.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKP00389.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region L_protein_N PF15518.6 RKP00389.1 - 0.095 12.5 0.0 14 5.6 0.1 2.3 2 0 0 2 2 2 0 L protein N-terminus Cbl_N PF02262.16 RKP00389.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 AAA_30 PF13604.6 RKP00389.1 - 0.52 10.0 3.3 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 AAA domain Leucyl-specific PF14795.6 RKP00390.1 - 0.026 14.6 0.1 0.17 12.0 0.1 2.5 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Lectin_N PF03954.14 RKP00390.1 - 0.03 14.1 0.8 0.03 14.1 0.8 6.4 3 2 3 6 6 6 0 Hepatic lectin, N-terminal domain Pox_A_type_inc PF04508.12 RKP00390.1 - 2 8.4 11.3 5 7.2 0.2 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat zf-C3HC PF07967.13 RKP00391.1 - 2e-25 89.3 0.0 3.7e-22 78.8 0.0 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 RKP00391.1 - 0.00031 20.8 11.0 0.0032 17.6 2.2 4.1 3 1 0 3 3 3 2 Rsm1-like RTT107_BRCT_5 PF16770.5 RKP00393.1 - 0.018 14.9 0.0 0.073 13.0 0.0 2.1 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 RKP00393.1 - 0.032 14.6 0.0 0.73 10.3 0.0 2.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PDEase_I PF00233.19 RKP00394.1 - 2.7e-78 263.0 0.1 3.8e-78 262.5 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 RKP00394.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal cNMP_binding PF00027.29 RKP00395.1 - 5.3e-15 55.3 0.3 1.3e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_4 PF12799.7 RKP00395.1 - 5.1e-09 36.3 6.4 0.027 14.9 0.1 5.0 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RKP00395.1 - 0.0001 22.1 11.9 9.9 6.5 0.0 8.0 8 0 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.6 RKP00395.1 - 0.024 14.4 3.0 19 5.1 0.1 4.2 4 1 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 RKP00395.1 - 0.078 13.6 13.3 18 6.4 0.0 7.6 9 0 0 9 9 9 0 Leucine Rich Repeat Zf_RING PF16744.5 RKP00395.1 - 0.16 12.1 0.9 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger WD40 PF00400.32 RKP00396.1 - 1.5e-41 139.6 14.2 3.9e-05 24.3 0.0 12.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00396.1 - 2e-20 72.9 0.4 0.18 12.1 0.0 8.4 5 1 2 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKP00396.1 - 1e-05 25.3 5.8 0.13 11.8 0.3 3.5 1 1 2 3 3 3 2 PQQ-like domain WD40_like PF17005.5 RKP00396.1 - 0.03 13.6 0.0 1.6 8.0 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain IKI3 PF04762.12 RKP00396.1 - 0.056 11.4 0.2 7.9 4.3 0.0 3.2 3 1 0 3 3 3 0 IKI3 family Ge1_WD40 PF16529.5 RKP00396.1 - 0.11 11.5 0.3 72 2.2 0.0 4.4 3 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-B_dimeris PF09026.10 RKP00397.1 - 0.63 10.5 12.2 4.9 7.6 0.4 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cpn60_TCP1 PF00118.24 RKP00398.1 - 5.8e-142 473.8 5.6 6.6e-142 473.6 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 RKP00398.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 RKP00398.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) PBD PF00786.28 RKP00399.1 - 1.4e-14 54.1 0.1 2.6e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 RKP00399.1 - 2.6e-14 53.1 0.0 4.9e-10 39.3 0.0 2.2 1 1 1 2 2 2 2 WH1 domain WH2 PF02205.20 RKP00399.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 WH2 motif Glyco_trans_1_4 PF13692.6 RKP00401.1 - 1e-20 74.5 0.1 2.9e-20 73.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 RKP00401.1 - 3.3e-18 65.8 0.0 1.7e-10 40.7 0.0 2.4 1 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RKP00401.1 - 7e-05 22.9 4.9 7e-05 22.9 4.9 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 RKP00401.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mito_fiss_reg PF05308.11 RKP00401.1 - 6.4 6.8 4.9 10 6.1 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.32 RKP00402.1 - 0.018 15.9 3.3 3.1 8.8 0.6 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat Macoilin PF09726.9 RKP00403.1 - 1.3 7.5 7.3 1.4 7.4 7.3 1.1 1 0 0 1 1 1 0 Macoilin family TRAPPC9-Trs120 PF08626.11 RKP00403.1 - 1.7 5.9 4.0 2.3 5.4 4.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit VWA_2 PF13519.6 RKP00404.1 - 1.9e-10 41.3 0.0 7.9e-10 39.3 0.0 2.1 2 2 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RKP00404.1 - 4.1e-10 40.2 0.0 3e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain SNAP-25 PF00835.19 RKP00404.1 - 0.032 14.5 0.1 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 SNAP-25 family VWA_CoxE PF05762.14 RKP00404.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Pkinase PF00069.25 RKP00405.1 - 3.6e-56 190.4 0.0 4.6e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00405.1 - 1.3e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RKP00405.1 - 0.0088 15.7 0.2 0.018 14.6 0.2 1.5 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 RKP00405.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP00405.1 - 0.035 13.4 2.0 0.12 11.7 0.4 2.4 2 1 0 2 2 2 0 Kinase-like Ral PF11058.8 RKP00405.1 - 0.039 13.5 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Antirestriction protein Ral FTA2 PF13095.6 RKP00405.1 - 0.1 12.2 0.1 0.58 9.7 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKP00405.1 - 0.14 12.1 0.1 0.59 10.0 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FUSC_2 PF13515.6 RKP00406.1 - 1.7e-17 63.7 17.3 1.7e-17 63.7 17.3 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 RKP00406.1 - 2.9e-14 52.6 14.5 2.9e-14 52.6 14.5 3.6 3 1 0 3 3 3 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 RKP00406.1 - 2.7e-11 43.7 0.5 9.5e-10 38.7 0.3 2.8 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 ALMT PF11744.8 RKP00406.1 - 6.6e-07 28.5 8.4 6.6e-07 28.5 8.4 1.9 2 0 0 2 2 2 1 Aluminium activated malate transporter AMP-binding PF00501.28 RKP00408.1 - 1.9e-93 313.4 0.1 2.7e-93 312.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RNA_pol_Rpb1_5 PF04998.17 RKP00408.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 UQ_con PF00179.26 RKP00409.1 - 9e-39 132.3 0.0 1.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKP00409.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 RKP00409.1 - 0.034 14.4 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Gtr1_RagA PF04670.12 RKP00410.1 - 1.5e-69 233.9 0.5 2e-69 233.5 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 RKP00410.1 - 0.00014 21.4 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RKP00410.1 - 0.00051 20.3 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RKP00410.1 - 0.00052 19.5 0.0 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RKP00410.1 - 0.0059 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKP00410.1 - 0.012 15.1 0.2 0.016 14.7 0.2 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 RKP00410.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKP00410.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain EMC3_TMCO1 PF01956.16 RKP00411.1 - 3.4e-53 179.9 1.1 4.7e-53 179.4 1.1 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF3155 PF11352.8 RKP00411.1 - 0.076 13.4 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) LRR_4 PF12799.7 RKP00412.1 - 1.3e-09 38.1 2.8 2.9e-06 27.5 0.2 2.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP00412.1 - 5.7e-07 29.2 7.6 2.9e-05 23.8 0.3 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 RKP00412.1 - 0.0046 16.9 1.6 8.5 6.7 0.1 3.5 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 RKP00412.1 - 0.018 15.5 2.3 12 7.0 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Bromodomain PF00439.25 RKP00413.1 - 1.5e-19 69.8 0.0 1.6e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Bromodomain SH3_1 PF00018.28 RKP00414.1 - 8e-09 35.0 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP00414.1 - 9.6e-09 35.0 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP00414.1 - 9.6e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ETRAMP PF09716.10 RKP00414.1 - 0.19 11.8 1.1 3.8 7.7 1.1 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SLD5_C PF16922.5 RKP00415.1 - 5.3e-14 52.2 0.0 7.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 RKP00415.1 - 0.00032 21.1 0.1 0.00052 20.4 0.1 1.5 1 1 0 1 1 1 1 GINS complex protein UQ_con PF00179.26 RKP00416.1 - 3.1e-40 137.1 0.0 3.5e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKP00416.1 - 0.052 13.3 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 RKP00416.1 - 0.069 13.4 0.0 0.16 12.3 0.0 1.6 2 0 0 2 2 2 0 RWD domain SCAI PF12070.8 RKP00417.1 - 8.6e-176 585.9 0.0 1e-175 585.7 0.0 1.0 1 0 0 1 1 1 1 Protein SCAI Transketolase_N PF00456.21 RKP00418.1 - 1e-150 501.3 0.1 2.8e-150 499.9 0.2 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RKP00418.1 - 2e-46 157.9 0.0 7.3e-46 156.1 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RKP00418.1 - 4.6e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 RKP00418.1 - 2e-05 24.0 0.0 5.8e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RKP00418.1 - 0.0032 17.3 0.4 0.2 11.5 0.7 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M49 PF03571.15 RKP00418.1 - 0.15 10.4 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M49 DnaJ PF00226.31 RKP00419.1 - 8.2e-11 41.9 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain FBPase PF00316.20 RKP00420.1 - 1.2e-71 240.1 0.1 1.6e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 RKP00420.1 - 0.024 14.2 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Inositol monophosphatase family Metallophos PF00149.28 RKP00421.1 - 4.6e-40 138.3 0.1 6e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKP00421.1 - 4.6e-22 78.2 1.1 1.1e-21 77.0 0.7 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Importin_rep PF18773.1 RKP00421.1 - 0.13 12.0 0.1 0.95 9.2 0.0 2.3 2 0 0 2 2 2 0 Importin 13 repeat Zn_clus PF00172.18 RKP00422.1 - 4.8e-05 23.4 12.2 0.00013 22.0 12.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 RKP00423.1 - 2.3e-09 37.7 0.8 0.027 15.3 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00423.1 - 0.029 14.7 0.0 5.8 7.3 0.0 3.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Spt20 PF12090.8 RKP00424.1 - 0.0052 16.4 7.7 0.0052 16.4 7.7 2.3 2 0 0 2 2 2 1 Spt20 family UPF0492 PF15744.5 RKP00424.1 - 0.021 14.1 9.5 0.043 13.0 9.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Hydin_ADK PF17213.3 RKP00424.1 - 0.33 11.2 2.8 1.3 9.3 2.8 2.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 RKP00424.1 - 0.94 8.2 5.1 2.1 7.0 5.1 1.6 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 RKP00424.1 - 1.3 8.9 7.8 5.1 7.0 7.8 2.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5349 PF17298.2 RKP00424.1 - 1.4 8.6 8.7 0.11 12.3 2.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5349) LRR_6 PF13516.6 RKP00426.1 - 1.1e-13 50.0 15.4 2.1e-05 24.2 0.2 6.0 6 0 0 6 6 5 4 Leucine Rich repeat LRR_1 PF00560.33 RKP00426.1 - 0.00042 20.5 0.1 21 6.2 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 RKP00426.1 - 0.0012 19.2 0.7 0.22 12.0 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Tropomyosin_1 PF12718.7 RKP00426.1 - 0.0067 16.6 12.2 0.0067 16.6 12.2 4.7 1 1 4 5 5 5 2 Tropomyosin like PKcGMP_CC PF16808.5 RKP00426.1 - 0.012 15.4 4.1 0.012 15.4 4.1 3.8 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BRI3BP PF14965.6 RKP00426.1 - 0.062 12.8 2.4 0.49 9.9 0.9 3.1 3 1 0 3 3 3 0 Negative regulator of p53/TP53 LRR_8 PF13855.6 RKP00426.1 - 0.075 12.8 6.6 5 7.0 0.3 3.0 1 1 1 2 2 2 0 Leucine rich repeat BLOC1_2 PF10046.9 RKP00426.1 - 0.075 13.3 18.9 0.074 13.4 3.1 4.6 3 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 RKP00426.1 - 0.14 12.1 38.4 0.11 12.5 10.4 4.5 3 1 1 4 4 4 0 FlxA-like protein ADIP PF11559.8 RKP00426.1 - 0.19 11.8 54.9 0.038 14.1 11.6 4.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Peptidase_S66 PF02016.15 RKP00426.1 - 0.59 10.3 4.9 0.42 10.7 0.3 2.8 1 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Fib_alpha PF08702.10 RKP00426.1 - 0.64 10.2 25.4 0.05 13.8 9.2 4.2 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family GAS PF13851.6 RKP00426.1 - 0.71 9.2 46.0 0.0094 15.3 21.5 3.5 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4988 PF16378.5 RKP00426.1 - 1.6 8.3 3.7 30 4.2 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF16 PF01519.16 RKP00426.1 - 2.3 8.7 22.9 1.1 9.7 2.0 3.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4618 PF15397.6 RKP00426.1 - 2.4 7.5 35.6 0.99 8.8 4.7 4.3 2 1 1 4 4 4 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 RKP00426.1 - 8.1 7.0 20.4 6.8 7.2 0.3 5.4 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF456 PF04306.13 RKP00427.1 - 0.49 10.7 10.5 2.4 8.4 10.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Brix PF04427.18 RKP00428.1 - 2.7e-25 89.6 0.7 4e-25 89.0 0.7 1.3 1 0 0 1 1 1 1 Brix domain Arf PF00025.21 RKP00429.1 - 1.5e-66 223.2 0.0 1.6e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RKP00429.1 - 1e-10 41.3 0.0 2.4e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RKP00429.1 - 2.9e-07 30.1 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RKP00429.1 - 3.4e-07 30.5 0.0 8.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RKP00429.1 - 5.1e-07 29.8 0.0 1e-06 28.8 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 RKP00429.1 - 3.6e-06 26.7 0.0 4.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RKP00429.1 - 1.8e-05 24.2 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RKP00429.1 - 0.043 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 RKP00430.1 - 6.1e-27 93.3 16.4 3.2e-06 27.8 0.0 6.8 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00430.1 - 4.2e-17 62.2 0.1 2.4e-05 24.6 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKP00430.1 - 2.7e-05 24.2 0.0 0.35 10.7 0.0 3.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RKP00430.1 - 0.0043 16.1 0.0 0.69 8.8 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Abhydrolase_1 PF00561.20 RKP00431.1 - 2.8e-05 23.9 0.1 0.00015 21.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 RKP00431.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 RKP00431.1 - 0.0033 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 RKP00431.1 - 0.027 14.0 0.0 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) ArfGap PF01412.18 RKP00433.1 - 3.5e-43 146.4 0.7 4.3e-43 146.1 0.7 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_L22 PF00237.19 RKP00434.1 - 1.7e-14 53.9 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Kinesin PF00225.23 RKP00437.1 - 1.1e-79 267.8 0.0 1.2e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP00437.1 - 2.7e-20 72.8 0.0 3.3e-17 62.8 0.0 2.8 1 1 1 2 2 2 2 Microtubule binding Pyrophosphatase PF00719.19 RKP00438.1 - 2e-54 183.7 0.1 2.4e-54 183.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PNP_UDP_1 PF01048.20 RKP00439.1 - 2.5e-44 151.3 2.7 3e-44 151.0 2.7 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily VRR_NUC PF08774.11 RKP00441.1 - 1.5e-10 41.1 0.0 3.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Parvo_coat_N PF08398.10 RKP00441.1 - 0.051 13.7 0.3 0.22 11.7 0.3 2.1 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Cpn60_TCP1 PF00118.24 RKP00442.1 - 2.6e-154 514.5 11.4 2.9e-154 514.4 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GLE1 PF07817.13 RKP00443.1 - 1.8e-51 174.8 0.0 3.2e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein CPSF100_C PF13299.6 RKP00443.1 - 6.7 6.9 5.5 14 5.8 5.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal tRNA-synt_2b PF00587.25 RKP00444.1 - 2.6e-32 112.2 0.0 4.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RKP00444.1 - 1.7e-06 28.1 0.0 3.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Zn-ribbon_8 PF09723.10 RKP00444.1 - 0.12 12.5 0.3 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 RKP00444.1 - 0.16 12.0 0.1 7.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 RKP00444.1 - 1.4 8.6 4.3 11 5.7 0.5 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Prok-RING_1 PF14446.6 RKP00444.1 - 4.9 7.2 5.2 21 5.1 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 LRR_8 PF13855.6 RKP00445.1 - 9.7e-12 44.5 5.8 5.2e-09 35.7 4.3 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RKP00445.1 - 9e-05 22.8 6.3 0.00072 19.9 1.8 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RKP00445.1 - 0.059 12.9 2.5 1.7 8.2 1.0 2.2 1 1 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 RKP00445.1 - 0.4 10.9 2.7 7.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat Phostensin_N PF13916.6 RKP00445.1 - 0.42 11.0 3.6 2.3 8.6 0.3 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal LRR_1 PF00560.33 RKP00445.1 - 1.9 9.3 5.8 8 7.4 0.0 3.7 3 1 1 4 4 4 0 Leucine Rich Repeat Glyco_hydro_46 PF01374.18 RKP00446.1 - 2.1e-23 83.0 4.0 3.4e-22 79.1 4.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 46 Thioredoxin PF00085.20 RKP00447.1 - 2e-16 59.9 0.2 2.4e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RKP00447.1 - 0.0017 17.4 0.0 0.0021 17.0 0.0 1.0 1 0 0 1 1 1 1 Phosducin OST3_OST6 PF04756.13 RKP00447.1 - 0.073 12.4 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family SNF2_N PF00176.23 RKP00448.1 - 6.2e-61 206.0 1.2 1.1e-60 205.2 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKP00448.1 - 4.6e-18 65.6 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 RKP00448.1 - 4.6e-14 52.1 0.6 9.1e-07 28.7 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 RKP00448.1 - 5.9e-06 26.4 0.0 1.6e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RKP00448.1 - 9.8e-06 24.9 0.1 8.6e-05 21.8 0.1 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ATP-synt_ab PF00006.25 RKP00449.1 - 2.5e-107 357.4 0.0 5.1e-107 356.3 0.0 1.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 RKP00449.1 - 4.2e-77 259.1 0.5 7.2e-77 258.4 0.5 1.4 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 RKP00449.1 - 9.9e-44 148.1 0.3 3.2e-43 146.5 0.0 2.0 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 RKP00449.1 - 1.1e-38 131.7 0.2 3.3e-32 110.9 0.1 2.8 3 0 0 3 3 3 2 Homing endonuclease ATP-synt_ab_N PF02874.23 RKP00449.1 - 8.7e-14 51.8 3.1 2.5e-13 50.3 3.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.6 RKP00449.1 - 4.6e-05 23.7 0.0 0.36 11.2 0.0 3.0 2 1 0 2 2 2 2 LAGLIDADG-like domain Hint_2 PF13403.6 RKP00449.1 - 0.00049 20.4 0.7 0.0015 18.8 0.7 1.8 1 0 0 1 1 1 1 Hint domain Hint PF01079.20 RKP00449.1 - 0.0042 16.6 0.2 0.0093 15.5 0.2 1.5 1 0 0 1 1 1 1 Hint module NuA4 PF09340.10 RKP00450.1 - 3.7e-19 68.4 0.0 6e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 AAA PF00004.29 RKP00451.1 - 7e-41 139.7 0.0 1.3e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKP00451.1 - 1.9e-08 34.0 0.1 4e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKP00451.1 - 1.3e-05 25.2 0.0 4e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKP00451.1 - 8.2e-05 23.0 0.1 0.0025 18.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP00451.1 - 0.00021 21.6 0.0 0.005 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 RKP00451.1 - 0.00068 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 RKP00451.1 - 0.00083 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 RKP00451.1 - 0.00099 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 RKP00451.1 - 0.0083 15.7 0.0 0.019 14.5 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 RKP00451.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKP00451.1 - 0.019 15.3 0.0 0.064 13.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 RKP00451.1 - 0.021 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 RKP00451.1 - 0.035 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 RKP00451.1 - 0.037 13.8 0.1 0.13 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 RKP00451.1 - 0.047 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 RKP00451.1 - 0.048 13.4 0.0 0.15 11.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 RKP00451.1 - 0.052 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RKP00451.1 - 0.053 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 RKP00451.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RKP00451.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 RKP00451.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 RKP00452.1 - 2e-55 187.2 0.1 2.9e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKP00452.1 - 1.5e-13 50.2 0.1 2.8e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PMT PF02366.18 RKP00453.1 - 4.5e-71 239.3 18.6 4.5e-71 239.3 18.6 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 RKP00453.1 - 1.1e-54 185.1 5.6 1.1e-30 106.7 6.2 3.0 4 0 0 4 4 4 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 RKP00453.1 - 9.3e-27 94.1 0.1 2.4e-26 92.7 0.1 1.6 1 1 0 1 1 1 1 MIR domain WD40 PF00400.32 RKP00454.1 - 9e-25 86.5 10.6 5.2e-05 23.9 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF1674 PF07896.12 RKP00454.1 - 2.2e-16 60.0 4.2 9.2e-16 58.1 4.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) ANAPC4_WD40 PF12894.7 RKP00454.1 - 5.7e-12 45.8 4.4 0.00085 19.6 0.1 4.8 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP00454.1 - 0.0054 15.7 0.0 0.016 14.2 0.0 1.7 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Septin PF00735.18 RKP00455.1 - 6e-27 94.6 0.0 7.1e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Septin eIF3g PF12353.8 RKP00457.1 - 6.4e-19 68.6 0.5 8.3e-19 68.2 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 RKP00457.1 - 7.8e-06 25.6 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Copper-fist PF00649.18 RKP00457.1 - 0.099 12.2 1.2 0.24 10.9 1.2 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain Glyco_hydro_114 PF03537.13 RKP00458.1 - 1.8e-53 181.2 0.2 2e-53 181.1 0.2 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Mito_carr PF00153.27 RKP00459.1 - 3.7e-73 241.5 0.4 2.3e-24 85.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TAP_C PF03943.13 RKP00460.1 - 1.9e-11 43.4 0.0 3.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain RRM_9 PF18444.1 RKP00460.1 - 3.7e-06 26.7 0.1 9.4e-05 22.2 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif LRR_4 PF12799.7 RKP00460.1 - 0.0039 17.6 0.5 0.013 15.9 0.0 2.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RKP00460.1 - 0.074 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 RKP00460.1 - 0.19 11.5 0.1 0.93 9.3 0.1 2.1 2 0 0 2 2 2 0 Leucine rich repeat Pkinase PF00069.25 RKP00461.1 - 2.8e-72 243.3 0.0 3.2e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00461.1 - 1e-41 143.0 0.0 1.3e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00461.1 - 8.9e-08 31.8 0.0 1.8e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RKP00461.1 - 1.5e-06 28.3 0.6 3.1e-06 27.3 0.6 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RKP00461.1 - 0.00049 19.5 0.9 0.0011 18.4 0.9 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RKP00461.1 - 0.002 17.8 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RKP00461.1 - 0.0029 16.6 0.1 0.0039 16.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 RKP00461.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 RKP00461.1 - 0.2 10.7 0.1 0.29 10.2 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.9 RKP00461.1 - 0.26 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Rad10 PF03834.14 RKP00462.1 - 6.2e-34 116.4 0.0 9.3e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 RKP00462.1 - 7.7e-09 36.0 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HRDC PF00570.23 RKP00462.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 HRDC domain HHH_2 PF12826.7 RKP00462.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Rib_5-P_isom_A PF06026.14 RKP00464.1 - 9e-45 152.4 0.0 1.7e-44 151.5 0.0 1.5 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) NAD_binding_10 PF13460.6 RKP00464.1 - 0.002 18.1 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Ribosomal_S19e PF01090.19 RKP00464.1 - 0.11 12.2 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S19e TBX PF12598.8 RKP00466.1 - 0.15 12.9 5.7 0.95 10.3 0.3 2.6 2 0 0 2 2 2 0 T-box transcription factor LETM1 PF07766.13 RKP00467.1 - 0.00033 20.1 0.1 0.00052 19.4 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein Ebp2 PF05890.12 RKP00468.1 - 3.6e-62 210.4 13.1 3.6e-62 210.4 13.1 1.5 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Phage_Mu_F PF04233.14 RKP00468.1 - 6.4 7.6 6.7 0.6 10.9 1.2 2.1 2 0 0 2 2 2 0 Phage Mu protein F like protein Rhodanese PF00581.20 RKP00469.1 - 4.3e-08 33.6 0.0 5.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 RKP00470.1 - 4.5e-11 43.2 0.0 5.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 RKP00471.1 - 0.16 12.9 0.3 6.5 7.8 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat CDC37_N PF03234.14 RKP00472.1 - 3.8e-28 99.0 3.7 3.8e-28 99.0 3.7 2.8 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 RKP00472.1 - 3.1e-12 46.5 0.3 8.3e-06 25.7 0.0 3.1 2 1 0 2 2 2 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 RKP00472.1 - 9.4e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Cdc37 C terminal domain UQ_con PF00179.26 RKP00473.1 - 3.4e-48 162.9 0.0 3.9e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1294 PF06961.13 RKP00474.1 - 3.8e-21 75.1 0.6 3.8e-21 75.1 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) zf-CCCH_2 PF14608.6 RKP00475.1 - 3.8e-12 46.2 42.8 0.00026 21.3 3.1 4.4 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 RKP00475.1 - 0.0002 21.5 3.7 0.34 11.2 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger containing family Nab2p_Zf1 PF18260.1 RKP00475.1 - 0.0028 17.5 1.8 0.0028 17.5 1.8 3.0 4 0 0 4 4 4 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf_CCCH_4 PF18345.1 RKP00475.1 - 0.0053 16.8 1.0 0.0053 16.8 1.0 5.3 4 2 0 4 4 4 1 Zinc finger domain zf-CCCH PF00642.24 RKP00475.1 - 0.032 14.2 0.4 0.032 14.2 0.4 5.6 5 2 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L23eN PF03939.13 RKP00476.1 - 6.7e-23 80.7 10.3 6.7e-23 80.7 10.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 RKP00476.1 - 2.4e-14 53.4 4.4 2.7e-14 53.3 0.7 2.6 2 1 0 2 2 2 1 Ribosomal protein L23 LAT PF15234.6 RKP00476.1 - 0.17 11.6 0.4 0.21 11.3 0.4 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells RhoGEF PF00621.20 RKP00477.1 - 3.2e-36 125.3 0.0 4.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 RKP00477.1 - 3e-18 65.3 8.1 3.8e-09 36.2 5.3 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RKP00477.1 - 3.2e-09 36.9 4.3 0.00015 22.1 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) EptA_B_N PF08019.12 RKP00477.1 - 0.036 13.9 0.3 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB LRR_1 PF00560.33 RKP00477.1 - 0.78 10.5 8.4 1.1e+02 4.0 0.8 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat Enkurin PF13864.6 RKP00478.1 - 4.3e-16 59.1 0.0 4.8e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Calmodulin-binding PH PF00169.29 RKP00479.1 - 0.00091 19.7 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RKP00479.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain PMT PF02366.18 RKP00480.1 - 9.4e-79 264.4 17.2 9.4e-79 264.4 17.2 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 RKP00480.1 - 1.5e-55 187.9 15.3 1.5e-55 187.9 15.3 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 RKP00480.1 - 1e-08 35.3 0.0 2.1e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 MIR domain zf-C2H2_aberr PF17017.5 RKP00481.1 - 0.017 15.2 5.0 0.48 10.5 0.6 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 RKP00481.1 - 0.14 12.4 0.1 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RKP00481.1 - 0.17 12.8 6.1 7.7 7.6 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 RKP00481.1 - 0.21 12.3 1.5 16 6.2 0.0 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 RKP00481.1 - 0.48 11.0 8.9 2 9.0 2.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type PQ-loop PF04193.14 RKP00482.1 - 2.1e-15 56.2 13.0 5.4e-10 38.9 0.9 2.7 3 0 0 3 3 3 2 PQ loop repeat Zn_peptidase_2 PF04298.12 RKP00482.1 - 0.026 14.0 0.9 0.047 13.1 0.9 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF3307 PF11750.8 RKP00482.1 - 0.027 14.5 0.1 0.67 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) Adeno_GP19K PF04881.13 RKP00482.1 - 0.077 13.0 0.4 0.19 11.7 0.4 1.6 1 0 0 1 1 1 0 Adenovirus GP19K NDUF_B12 PF08122.12 RKP00482.1 - 2.8 8.1 4.9 0.99 9.5 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family BIR PF00653.21 RKP00483.1 - 1.2e-31 109.2 0.7 1e-15 58.1 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 RKP00483.1 - 0.0019 18.2 0.1 0.015 15.3 0.0 2.3 2 1 0 3 3 3 1 C3HC zinc finger-like FXMRP1_C_core PF12235.8 RKP00483.1 - 1.7 9.3 5.8 4.4 8.0 5.8 1.9 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal WD40 PF00400.32 RKP00485.1 - 3.4e-06 27.7 1.1 0.026 15.4 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat TFIID_30kDa PF03540.13 RKP00486.1 - 1.8e-24 85.4 0.3 3.1e-24 84.7 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Thioredoxin PF00085.20 RKP00487.1 - 1e-08 35.1 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin CcmD PF04995.14 RKP00487.1 - 0.023 14.8 4.0 0.094 12.8 4.0 2.1 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rav1p_C PF12234.8 RKP00488.1 - 4.6e-53 180.6 2.4 2.6e-49 168.2 2.3 2.7 3 0 0 3 3 3 2 RAVE protein 1 C terminal WD40 PF00400.32 RKP00488.1 - 1.1e-09 38.8 9.6 0.012 16.4 0.0 8.4 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00488.1 - 3.5e-05 24.0 0.1 0.0011 19.2 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PKS_DE PF18369.1 RKP00488.1 - 0.063 13.9 0.4 0.35 11.5 0.4 2.4 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain ENTH PF01417.20 RKP00489.1 - 4.8e-45 152.6 1.1 4.9e-45 152.6 0.3 1.4 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 RKP00489.1 - 8.1e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 RKP00489.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 VHS domain DUF1451 PF07295.11 RKP00489.1 - 0.12 12.4 0.1 0.28 11.2 0.1 1.7 1 1 0 1 1 1 0 Zinc-ribbon containing domain Fib_alpha PF08702.10 RKP00489.1 - 0.99 9.6 4.1 1 9.5 0.1 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Mcl1_mid PF12341.8 RKP00490.1 - 6.6e-07 29.0 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region F-box-like PF12937.7 RKP00491.1 - 4.4e-06 26.5 0.3 1.2e-05 25.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RKP00491.1 - 6.5e-05 22.7 0.2 0.00021 21.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 RKP00491.1 - 0.00085 19.2 0.1 0.0024 17.8 0.1 1.7 1 0 0 1 1 1 1 F-box MerR-DNA-bind PF09278.11 RKP00492.1 - 0.24 12.0 2.4 0.92 10.1 1.7 2.3 2 0 0 2 2 2 0 MerR, DNA binding SWIRM PF04433.17 RKP00493.1 - 7e-18 64.8 0.0 4.4e-17 62.2 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain Prok-JAB PF14464.6 RKP00493.1 - 7.6e-07 28.9 0.7 1.9e-06 27.7 0.7 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 RKP00493.1 - 3.9e-06 26.8 0.0 8.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4554 PF15091.6 RKP00493.1 - 8.2 5.2 7.1 15 4.3 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SH3_1 PF00018.28 RKP00494.1 - 7.4e-39 131.1 1.4 1.3e-13 50.3 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 RKP00494.1 - 3.7e-28 97.1 5.7 1.8e-11 43.7 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 RKP00494.1 - 1.4e-25 88.9 0.0 3.5e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 RKP00494.1 - 4.3e-22 77.5 0.0 5.4e-08 32.4 0.0 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 RKP00494.1 - 1e-05 25.5 0.0 0.11 12.6 0.0 3.6 3 0 0 3 3 3 2 SH3 domain SAM_4 PF18017.1 RKP00494.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Apolipoprotein PF01442.18 RKP00496.1 - 3.1e-06 27.2 33.7 0.00044 20.2 14.4 2.8 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Borrelia_P83 PF05262.11 RKP00496.1 - 0.061 11.8 23.4 0.074 11.5 22.9 1.4 1 1 0 1 1 1 0 Borrelia P83/100 protein Phasin_2 PF09361.10 RKP00496.1 - 0.67 10.3 45.7 2.6 8.4 18.5 3.1 1 1 0 2 2 2 0 Phasin protein TipAS PF07739.13 RKP00496.1 - 1.5 9.4 19.4 0.38 11.3 11.1 2.7 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain Muted PF14942.6 RKP00496.1 - 2.5 8.4 7.9 5.3 7.4 4.7 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.13 RKP00496.1 - 3 8.5 47.0 2.2 8.9 12.8 4.8 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) Adaptin_N PF01602.20 RKP00497.1 - 3.5e-113 378.9 0.0 4.1e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKP00497.1 - 5.6e-08 33.0 0.0 8.1e-07 29.2 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CRISPR_Cse2 PF09485.10 RKP00497.1 - 0.0052 17.3 0.1 0.016 15.8 0.1 1.8 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) HEAT PF02985.22 RKP00497.1 - 0.0079 16.4 0.4 12 6.5 0.0 4.9 4 1 1 5 5 5 1 HEAT repeat Ribosomal_L28 PF00830.19 RKP00499.1 - 0.0012 18.9 0.1 0.0023 18.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L28 family DUF2526 PF10735.9 RKP00499.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Methyltransf_28 PF02636.17 RKP00500.1 - 1.6e-63 214.8 0.0 2.1e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Swi3 PF07962.12 RKP00501.1 - 1.4e-16 60.2 0.0 2.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 PAP2_3 PF14378.6 RKP00503.1 - 8.8e-24 84.2 17.8 1.4e-23 83.6 17.8 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 RKP00503.1 - 3.6e-06 26.8 9.6 4.5e-06 26.5 8.0 2.1 1 1 1 2 2 2 1 PAP2 superfamily ADK PF00406.22 RKP00504.1 - 0.00079 19.5 0.0 0.097 12.8 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase DUF5582 PF17819.1 RKP00504.1 - 0.03 14.8 0.1 0.048 14.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF5586 PF17824.1 RKP00504.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DDOST_48kD PF03345.14 RKP00505.1 - 3.6e-85 286.3 0.0 4e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta SelP_N PF04592.14 RKP00507.1 - 0.00027 20.4 17.3 0.00048 19.6 17.3 1.3 1 0 0 1 1 1 1 Selenoprotein P, N terminal region SR-25 PF10500.9 RKP00507.1 - 0.0091 15.6 1.5 0.0091 15.6 1.5 3.3 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Methyltransf_16 PF10294.9 RKP00508.1 - 3.1e-08 33.6 0.0 9.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 RKP00508.1 - 0.00044 20.1 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKP00508.1 - 0.014 15.2 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 RKP00508.1 - 0.026 14.1 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_S27e PF01667.17 RKP00509.1 - 7.6e-27 92.8 5.6 9e-27 92.6 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 RKP00509.1 - 0.11 12.3 1.3 0.2 11.4 1.3 1.4 1 1 0 1 1 1 0 CSL zinc finger MAS20 PF02064.15 RKP00510.1 - 4.7e-27 94.6 0.0 5.4e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_1 PF00515.28 RKP00510.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Lon_C PF05362.13 RKP00511.1 - 1.3e-77 260.0 0.0 2.4e-77 259.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 RKP00511.1 - 1.1e-20 74.3 0.0 2.6e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKP00511.1 - 4.9e-10 39.6 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 RKP00511.1 - 1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 RKP00511.1 - 0.00012 22.3 0.0 0.00033 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) LON_substr_bdg PF02190.16 RKP00511.1 - 0.00039 20.3 0.0 0.0008 19.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_22 PF13401.6 RKP00511.1 - 0.0005 20.3 0.7 0.011 16.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 RKP00511.1 - 0.00066 20.1 7.2 0.0058 17.0 0.1 3.7 3 1 1 4 4 4 1 AAA ATPase domain NACHT PF05729.12 RKP00511.1 - 0.01 15.8 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 RKP00511.1 - 0.018 14.9 0.0 0.042 13.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RKP00511.1 - 0.026 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 RKP00511.1 - 0.036 14.0 0.0 2 8.3 0.0 2.4 1 1 1 2 2 2 0 NTPase RsgA_GTPase PF03193.16 RKP00511.1 - 0.047 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SKI PF01202.22 RKP00511.1 - 0.059 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.6 RKP00511.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RKP00511.1 - 0.097 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RKP00511.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 RKP00511.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TRIQK PF15168.6 RKP00512.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family DSPc PF00782.20 RKP00513.1 - 2.7e-22 79.0 0.0 3.1e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 RKP00513.1 - 5.9e-05 23.3 0.0 7.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 RKP00513.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TBCA PF02970.16 RKP00515.1 - 2.1e-18 66.4 0.2 2.2e-18 66.4 0.2 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A NTF2 PF02136.20 RKP00516.1 - 2.4e-36 124.9 0.3 2.7e-36 124.7 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Tim17 PF02466.19 RKP00517.1 - 1.4e-26 93.0 7.9 2.2e-26 92.4 7.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Acyl-CoA_dh_1 PF00441.24 RKP00518.1 - 1.2e-13 51.6 1.1 1.3e-13 51.4 1.1 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 RKP00518.1 - 0.00012 22.3 0.3 0.00019 21.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bd3614-deam PF14439.6 RKP00519.1 - 0.084 12.9 1.1 0.17 12.0 1.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase zf-CCCH PF00642.24 RKP00520.1 - 2.4e-18 65.5 34.5 4.4e-06 26.5 0.3 5.1 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RKP00520.1 - 1.5e-15 56.6 37.2 7.4e-07 29.0 1.9 5.9 5 1 0 5 5 5 5 Zinc finger domain Torus PF16131.5 RKP00520.1 - 1.6e-10 41.7 27.4 6e-05 23.7 0.4 5.0 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 RKP00520.1 - 3.8e-07 29.8 34.5 5.4e-06 26.1 0.4 4.9 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 RKP00520.1 - 9.9e-06 25.7 10.5 9.9e-06 25.7 10.5 3.0 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 RKP00520.1 - 0.00067 20.0 29.9 0.013 16.0 0.2 5.6 5 1 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 RKP00521.1 - 3.6e-14 53.1 1.3 3.1e-10 40.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKP00521.1 - 5.4e-13 48.9 4.7 4e-08 33.4 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RKP00521.1 - 4.7e-11 42.6 3.2 0.0029 18.0 0.6 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RKP00521.1 - 5.5e-11 42.8 1.3 1.9e-07 31.5 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP00521.1 - 1e-09 37.8 1.3 0.002 18.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 RKP00522.1 - 6.2e-14 52.4 0.6 8.8e-14 51.9 0.6 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKP00522.1 - 7.3e-14 50.5 1.8 5.8e-05 23.2 0.5 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 RKP00522.1 - 9.7e-13 48.4 5.8 5.6e-08 33.2 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RKP00522.1 - 6.7e-12 45.3 5.3 2.6e-05 24.5 1.5 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RKP00522.1 - 1.6e-06 28.3 3.6 0.0052 17.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) LSM PF01423.22 RKP00523.1 - 1.7e-18 66.1 0.1 1.9e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKP00523.1 - 0.068 13.3 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 RKP00523.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Ribosomal_L26 PF16906.5 RKP00524.1 - 1.1e-31 109.2 1.3 1.3e-31 108.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 RKP00524.1 - 2.8e-08 33.4 1.8 6.4e-08 32.3 1.8 1.6 1 0 0 1 1 1 1 KOW motif Adeno_VII PF03228.14 RKP00524.1 - 0.0036 17.9 0.4 0.0051 17.4 0.3 1.4 1 1 0 1 1 1 1 Adenoviral core protein VII Glyoxalase PF00903.25 RKP00525.1 - 2.4e-17 63.3 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RKP00525.1 - 4.3e-08 33.4 0.0 5.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 RKP00525.1 - 0.0066 16.4 0.0 0.0091 15.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 RKP00525.1 - 0.01 16.6 0.0 0.016 16.0 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 RKP00525.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DUF21 PF01595.20 RKP00526.1 - 2.1e-32 112.2 0.0 3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RKP00526.1 - 3e-05 24.4 0.4 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 1 CBS domain GPI-anchored PF10342.9 RKP00527.1 - 9.5e-05 23.1 1.3 9.5e-05 23.1 1.3 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Herpes_UL32 PF06070.11 RKP00527.1 - 1.6 6.4 6.6 1.9 6.1 6.6 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Ribosomal_S14 PF00253.21 RKP00528.1 - 9.2e-19 67.0 0.0 1.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e STAG PF08514.11 RKP00529.1 - 7e-12 45.3 3.1 8.8e-12 44.9 0.0 2.8 3 1 1 4 4 4 1 STAG domain FemAB PF02388.16 RKP00529.1 - 0.098 11.5 1.1 0.2 10.5 1.1 1.4 1 0 0 1 1 1 0 FemAB family OmpH PF03938.14 RKP00529.1 - 0.21 11.9 6.3 0.89 9.9 6.3 2.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMCO5 PF14992.6 RKP00529.1 - 0.22 11.1 0.8 0.4 10.2 0.8 1.3 1 0 0 1 1 1 0 TMCO5 family Nucleopor_Nup85 PF07575.13 RKP00530.1 - 1.3e-61 208.9 0.0 1.7e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin TTL PF03133.15 RKP00531.1 - 2.7e-75 253.2 0.0 4.8e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RKP00531.1 - 1.4e-08 34.3 0.1 1.2e-05 24.7 0.0 3.3 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RKP00531.1 - 3.5e-05 23.2 0.0 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RKP00531.1 - 0.019 15.0 0.0 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain SRP54 PF00448.22 RKP00532.1 - 3.2e-66 222.7 0.5 4.4e-53 179.8 0.0 2.8 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 RKP00532.1 - 4.5e-23 81.7 0.7 4.5e-23 81.7 0.7 3.3 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 RKP00532.1 - 5.6e-17 61.7 0.7 1.3e-16 60.6 0.7 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 RKP00532.1 - 2.8e-05 24.6 1.3 0.00054 20.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP00532.1 - 4.4e-05 23.8 0.9 0.0036 17.6 0.3 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RKP00532.1 - 8.8e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.19 RKP00532.1 - 0.00012 21.7 0.6 0.0029 17.2 0.6 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 RKP00532.1 - 0.00029 21.3 2.2 0.0015 18.9 0.1 2.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RKP00532.1 - 0.00099 19.3 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP00532.1 - 0.0011 19.6 0.2 0.0027 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 RKP00532.1 - 0.0022 17.8 0.0 0.0081 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKP00532.1 - 0.01 16.1 0.6 0.019 15.2 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 RKP00532.1 - 0.01 16.1 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 RKP00532.1 - 0.016 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_25 PF13481.6 RKP00532.1 - 0.017 14.7 0.2 0.046 13.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 RKP00532.1 - 0.022 14.8 0.0 0.074 13.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase EcsC PF12787.7 RKP00532.1 - 0.025 14.2 0.9 0.057 13.1 0.9 1.6 1 0 0 1 1 1 0 EcsC protein family SRPRB PF09439.10 RKP00532.1 - 0.025 14.0 0.1 2 7.8 0.1 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Methyltransf_25 PF13649.6 RKP00532.1 - 0.065 14.0 0.3 0.42 11.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain AAA_14 PF13173.6 RKP00532.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 RKP00532.1 - 0.11 12.4 0.4 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 RKP00532.1 - 0.11 12.2 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Thymidylate kinase Rad17 PF03215.15 RKP00532.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 RKP00532.1 - 0.14 12.6 0.3 0.51 10.8 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKP00532.1 - 0.15 12.5 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arf PF00025.21 RKP00532.1 - 0.15 11.5 0.1 0.35 10.3 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family SWI2_SNF2 PF18766.1 RKP00532.1 - 0.28 10.8 1.4 23 4.5 0.0 2.8 1 1 1 3 3 3 0 SWI2/SNF2 ATPase DUF2587 PF10759.9 RKP00532.1 - 0.4 10.2 5.0 1.3 8.5 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) ADK PF00406.22 RKP00532.1 - 0.9 9.6 4.6 1.9 8.6 0.1 2.9 3 0 0 3 3 3 0 Adenylate kinase CBFD_NFYB_HMF PF00808.23 RKP00533.1 - 0.0018 18.5 0.1 0.32 11.3 0.0 2.9 3 0 0 3 3 3 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SpoIIIAH PF12685.7 RKP00534.1 - 1.1 9.0 7.6 2.1 8.1 7.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Mito_carr PF00153.27 RKP00535.1 - 3.7e-52 174.2 6.4 5.2e-20 71.2 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein DEC-1_N PF04625.13 RKP00535.1 - 0.63 9.0 5.0 0.83 8.6 5.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FancD2 PF14631.6 RKP00536.1 - 5.3e-64 216.4 0.0 1.5e-54 185.1 0.0 2.6 2 1 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 RKP00536.1 - 0.046 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 FANCI solenoid 2 EMP24_GP25L PF01105.24 RKP00537.1 - 1.1e-40 139.6 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LRR_6 PF13516.6 RKP00538.1 - 5.5e-13 47.8 3.4 0.0016 18.4 0.0 6.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_8 PF13855.6 RKP00538.1 - 0.053 13.3 3.6 7.8 6.4 0.1 4.2 4 1 1 5 5 5 0 Leucine rich repeat Tim17 PF02466.19 RKP00539.1 - 2.5 8.5 8.9 2.3 8.6 5.8 2.5 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 RKP00540.1 - 2.4e-43 145.3 9.8 1.7e-08 34.9 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 RKP00540.1 - 1.5e-37 128.8 0.3 2.4e-37 128.1 0.3 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 RKP00540.1 - 2.7e-11 43.6 0.0 0.042 14.1 0.0 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RKP00540.1 - 3.9e-05 23.1 0.0 0.21 10.9 0.0 3.1 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 RKP00540.1 - 0.0013 17.8 0.0 0.21 10.5 0.0 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 RKP00540.1 - 0.0072 16.2 0.0 0.028 14.4 0.0 2.1 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 RKP00540.1 - 0.053 13.4 0.0 0.68 9.8 0.0 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 RKP00540.1 - 0.12 12.1 2.8 0.61 9.8 0.1 2.3 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Bot1p PF12298.8 RKP00541.1 - 1.2e-10 41.8 8.7 1.9e-09 38.0 4.3 3.1 1 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein DUF515 PF04415.12 RKP00541.1 - 2.9 6.2 6.2 4.1 5.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RabGAP-TBC PF00566.18 RKP00542.1 - 4e-47 160.7 0.1 6.7e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 RKP00542.1 - 2.6e-14 53.1 0.0 1.3e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 GRAM domain DUF4668 PF15701.5 RKP00542.1 - 0.048 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) eIF-1a PF01176.19 RKP00544.1 - 1.3e-18 66.5 0.0 1.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TRAPP PF04051.16 RKP00546.1 - 1.4e-34 119.0 0.0 1.6e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Peptidase_S24 PF00717.23 RKP00547.1 - 4.2e-09 36.2 0.1 2.7e-08 33.6 0.0 2.2 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 RKP00547.1 - 0.0081 15.9 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Menin PF05053.13 RKP00548.1 - 2.5 6.3 4.0 3.6 5.8 4.0 1.1 1 0 0 1 1 1 0 Menin DHO_dh PF01180.21 RKP00549.1 - 5.8e-91 304.8 0.0 6.7e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 RKP00549.1 - 0.035 13.1 1.2 0.81 8.7 0.9 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NMO PF03060.15 RKP00549.1 - 0.19 11.1 5.0 0.13 11.7 3.1 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase Pkinase PF00069.25 RKP00550.1 - 1.2e-56 192.0 0.0 2.3e-54 184.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00550.1 - 1.2e-27 96.8 0.0 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00550.1 - 9.3e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP00550.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRIMA1 PF16101.5 RKP00550.1 - 4.3 7.4 10.2 9.8 6.2 10.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TPR_2 PF07719.17 RKP00551.1 - 2.3e-14 52.3 37.8 0.0013 18.7 1.1 13.6 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 RKP00551.1 - 1.8e-11 43.3 12.4 0.015 15.1 0.9 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 RKP00551.1 - 1.5e-09 37.2 24.6 0.096 12.8 0.1 9.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 RKP00551.1 - 3.8e-09 36.0 1.6 0.47 10.8 0.8 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKP00551.1 - 0.00012 21.7 5.7 0.35 10.6 1.2 5.2 5 0 0 5 5 5 1 TPR repeat TPR_12 PF13424.6 RKP00551.1 - 0.00051 20.3 0.5 0.013 15.8 0.1 12.2 11 2 3 14 14 13 5 Tetratricopeptide repeat TPR_16 PF13432.6 RKP00551.1 - 0.007 17.0 2.5 0.007 17.0 2.5 21.5 23 2 1 24 24 16 5 Tetratricopeptide repeat TPR_19 PF14559.6 RKP00551.1 - 0.0082 16.6 0.0 0.0082 16.6 0.0 14.0 14 3 2 16 16 12 4 Tetratricopeptide repeat TPR_10 PF13374.6 RKP00551.1 - 0.03 14.2 38.8 0.61 10.0 0.6 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF2269 PF10027.9 RKP00551.1 - 0.031 14.3 0.5 0.28 11.3 0.5 2.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) ANAPC3 PF12895.7 RKP00551.1 - 0.33 11.2 0.0 0.33 11.2 0.0 6.9 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Trs65 PF12735.7 RKP00552.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 RNA_pol_A_bac PF01000.26 RKP00553.1 - 1.7e-26 92.8 0.0 3.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RKP00553.1 - 1.2e-20 72.7 0.0 1.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UBN_AB PF14075.6 RKP00554.1 - 4.8e-19 68.9 0.0 4.8e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 RKP00554.1 - 0.00042 20.3 1.1 0.00092 19.2 1.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Peptidase_S49 PF01343.18 RKP00556.1 - 5.6e-41 140.1 0.0 6.1e-29 101.0 0.0 3.3 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.23 RKP00556.1 - 1.3e-05 25.2 2.0 0.11 12.4 0.0 3.6 4 0 0 4 4 4 2 Clp protease Sgf11 PF08209.11 RKP00557.1 - 4e-08 32.7 2.0 4e-08 32.7 2.0 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) NS3_envE PF02723.14 RKP00557.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Zn_Tnp_IS1595 PF12760.7 RKP00557.1 - 0.16 12.0 5.0 0.31 11.0 5.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 RKP00557.1 - 0.16 11.9 2.9 0.39 10.7 2.9 1.6 1 1 1 2 2 2 0 zinc-ribbons Cytochrome_C7 PF14522.6 RKP00557.1 - 0.18 11.8 7.1 0.5 10.4 7.2 1.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Period_C PF12114.8 RKP00557.1 - 0.51 9.9 1.9 0.73 9.4 1.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Zn-ribbon_8 PF09723.10 RKP00557.1 - 1.3 9.2 5.4 17 5.6 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain RCC1 PF00415.18 RKP00558.1 - 3.3e-71 235.7 18.0 6.7e-12 45.9 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKP00558.1 - 2.7e-27 93.9 37.1 3.4e-07 29.9 1.8 9.0 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat Med7 PF05983.11 RKP00559.1 - 5.2e-17 62.6 0.0 1.3e-16 61.3 0.0 1.8 1 1 0 1 1 1 1 MED7 protein MSA_2 PF00985.17 RKP00559.1 - 0.088 13.2 0.3 0.088 13.2 0.3 2.5 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family APH PF01636.23 RKP00559.1 - 0.43 10.5 9.6 0.75 9.7 9.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family COG5 PF10392.9 RKP00560.1 - 4.9e-13 49.4 3.4 5.8e-13 49.2 1.6 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 RKP00560.1 - 0.014 15.4 0.6 0.11 12.6 0.4 2.5 2 0 0 2 2 2 0 Vps51/Vps67 Arg_decarbox_C PF17944.1 RKP00560.1 - 0.071 13.7 2.2 13 6.4 0.4 3.9 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension COG6 PF06419.11 RKP00560.1 - 1.1 7.4 4.6 2.7 6.1 2.7 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Baculo_PEP_C PF04513.12 RKP00560.1 - 9.8 6.2 6.6 23 5.0 1.2 3.7 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CPSase_L_D2 PF02786.17 RKP00562.1 - 4.4e-93 310.6 0.0 1.2e-80 270.0 0.0 2.6 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 RKP00562.1 - 6.9e-37 126.5 0.2 1.7e-36 125.2 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 RKP00562.1 - 6.1e-12 45.5 0.0 3.9e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RKP00562.1 - 1.8e-11 44.0 0.0 1.2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 RKP00562.1 - 2.7e-07 30.4 0.1 0.018 14.8 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 RKP00562.1 - 0.00022 20.9 0.0 0.045 13.3 0.0 2.7 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 RKP00562.1 - 0.0008 18.9 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain HTH_23 PF13384.6 RKP00562.1 - 0.0096 15.7 0.4 0.4 10.5 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain Semialdhyde_dh PF01118.24 RKP00562.1 - 0.12 12.9 0.0 0.41 11.1 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Med31 PF05669.12 RKP00563.1 - 1.3e-35 121.3 9.5 1.4e-35 121.1 9.5 1.0 1 0 0 1 1 1 1 SOH1 BRO1 PF03097.18 RKP00564.1 - 1.1e-50 172.6 0.6 2e-50 171.8 0.6 1.3 1 0 0 1 1 1 1 BRO1-like domain Laminin_B PF00052.18 RKP00564.1 - 0.068 13.1 0.5 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 Laminin B (Domain IV) DUF4396 PF14342.6 RKP00564.1 - 0.2 12.0 1.0 0.42 11.0 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) TRAM_LAG1_CLN8 PF03798.16 RKP00565.1 - 8.9e-18 64.7 21.3 1.2e-17 64.3 21.3 1.2 1 0 0 1 1 1 1 TLC domain Tom7 PF08038.12 RKP00566.1 - 2.6e-15 55.8 0.1 2.9e-15 55.6 0.1 1.0 1 0 0 1 1 1 1 TOM7 family DNAPolymera_Pol PF11590.8 RKP00566.1 - 0.22 11.5 0.8 0.78 9.7 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase catalytic subunit Pol HECT PF00632.25 RKP00567.1 - 1.9e-88 296.9 0.0 2.2e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PAC3 PF10178.9 RKP00569.1 - 0.0094 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 KH_8 PF17903.1 RKP00570.1 - 5.3e-30 103.3 0.0 1e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 RKP00570.1 - 0.00082 19.1 0.0 0.0032 17.3 0.0 2.0 2 1 0 2 2 2 1 KH domain Alpha_GJ PF03229.13 RKP00570.1 - 1.5 9.3 8.9 1.1 9.8 0.3 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J Mitofilin PF09731.9 RKP00571.1 - 5.6e-47 160.9 47.3 1.4e-38 133.2 41.1 3.1 1 1 0 2 2 2 2 Mitochondrial inner membrane protein DUF826 PF05696.11 RKP00571.1 - 0.024 14.7 0.5 0.11 12.6 0.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF826) PilX_N PF14341.6 RKP00571.1 - 0.081 12.9 1.3 0.4 10.7 1.3 2.3 1 0 0 1 1 1 0 PilX N-terminal Nrap_D4 PF17405.2 RKP00572.1 - 2e-26 92.7 0.3 1.1e-25 90.3 0.1 2.0 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 RKP00572.1 - 1.2e-21 77.2 0.0 2.4e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 RKP00572.1 - 6e-20 71.6 0.0 3.6e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 RKP00572.1 - 2.8e-16 59.9 0.0 5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 RKP00572.1 - 3.1e-14 53.3 0.1 1e-13 51.6 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 RKP00572.1 - 4.2e-11 43.2 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Cwf_Cwc_15 PF04889.12 RKP00572.1 - 0.36 10.5 10.5 0.64 9.7 10.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 RKP00572.1 - 1.1 7.4 5.7 1.6 6.9 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 RKP00572.1 - 2.8 7.7 8.3 4.9 6.9 8.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 RKP00572.1 - 5.9 4.9 13.4 9.1 4.2 13.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Acyltransferase PF01553.21 RKP00574.1 - 2.1e-32 111.5 0.0 3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TRAPPC-Trs85 PF12739.7 RKP00575.1 - 2.1e-71 241.1 0.0 1.7e-70 238.1 0.0 2.3 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2059 PF09832.9 RKP00575.1 - 0.077 13.1 1.8 0.14 12.2 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) zf-H2C2_2 PF13465.6 RKP00576.1 - 1.9e-10 40.7 19.1 8.7e-07 29.1 2.2 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKP00576.1 - 3.1e-09 36.8 24.3 0.00096 19.5 7.8 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RKP00576.1 - 9e-06 25.8 8.2 0.08 13.3 3.0 3.1 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RKP00576.1 - 1.5e-05 25.4 22.5 0.029 15.2 7.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 RKP00576.1 - 0.0003 21.1 9.7 0.87 10.1 1.7 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RKP00576.1 - 0.00032 20.6 20.7 0.28 11.2 1.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-FCS PF06467.14 RKP00576.1 - 0.013 15.4 0.3 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 RKP00576.1 - 0.2 12.3 6.3 1.3 9.7 2.0 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 RKP00576.1 - 0.82 9.5 16.4 5.9 6.8 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 RKP00576.1 - 1.8 9.1 10.5 3.9 8.0 4.7 2.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger STI1 PF17830.1 RKP00577.1 - 0.058 13.3 0.3 0.64 10.0 0.2 2.4 2 0 0 2 2 2 0 STI1 domain DUF1394 PF07159.12 RKP00579.1 - 6.1e-90 301.5 0.0 7.3e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) TMEM234 PF10639.9 RKP00580.1 - 0.0011 19.0 0.8 0.0036 17.3 0.4 1.8 2 0 0 2 2 2 1 Putative transmembrane family 234 Bac_rhodopsin PF01036.18 RKP00580.1 - 0.0081 15.8 0.3 0.016 14.8 0.2 1.5 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein EamA PF00892.20 RKP00580.1 - 0.014 15.6 10.0 0.46 10.6 9.9 2.0 1 1 0 1 1 1 0 EamA-like transporter family Aa_trans PF01490.18 RKP00581.1 - 2.4e-77 260.4 27.7 2.7e-77 260.2 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RKP00581.1 - 1.5e-08 34.1 19.5 1.5e-08 34.1 19.5 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family efThoc1 PF11957.8 RKP00582.1 - 6.3e-62 209.8 0.0 8.3e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor SYS1 PF09801.9 RKP00583.1 - 3.9e-28 98.4 0.1 4.5e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PUNUT PF16913.5 RKP00583.1 - 0.00064 19.0 1.9 0.0008 18.7 0.4 1.7 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport Actin PF00022.19 RKP00584.1 - 1.1e-113 380.0 0.0 8.8e-113 377.0 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RKP00584.1 - 0.024 13.4 0.0 0.064 12.1 0.0 1.6 1 1 0 1 1 1 0 MreB/Mbl protein UCH PF00443.29 RKP00585.1 - 1.6e-52 178.6 0.0 1.9e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP00585.1 - 1e-12 48.3 0.2 3.8e-12 46.4 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RKP00585.1 - 1.5e-10 40.6 0.6 4.4e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family PNP_UDP_1 PF01048.20 RKP00585.1 - 0.067 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphorylase superfamily IFT81_CH PF18383.1 RKP00585.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain SLX9 PF15341.6 RKP00586.1 - 8.4e-08 32.7 1.8 1.7e-07 31.7 1.8 1.5 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 CorA PF01544.18 RKP00587.1 - 1.4e-05 24.5 4.3 2.4e-05 23.8 4.3 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF211 PF02680.14 RKP00587.1 - 0.16 12.2 0.8 11 6.3 0.0 3.3 3 1 1 4 4 4 0 Uncharacterized ArCR, COG1888 Baculo_PEP_C PF04513.12 RKP00587.1 - 0.57 10.2 4.8 0.66 10.0 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus E1-E2_ATPase PF00122.20 RKP00591.1 - 5e-39 133.7 2.6 9.3e-38 129.6 0.2 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RKP00591.1 - 1.3e-18 68.1 0.0 2.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKP00591.1 - 1.2e-07 31.3 0.0 3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKP00591.1 - 0.0016 18.3 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GNVR PF13807.6 RKP00591.1 - 0.089 12.7 0.1 4.9 7.1 0.0 2.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase YrvL PF14184.6 RKP00591.1 - 3.1 7.9 10.9 0.064 13.4 3.1 2.1 2 0 0 2 2 2 0 Regulatory protein YrvL Ribosomal_L7Ae PF01248.26 RKP00592.1 - 8.3e-25 86.4 0.0 1.1e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 RKP00592.1 - 0.00074 19.4 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 RKP00592.1 - 0.072 13.1 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 UPF0121 PF03661.13 RKP00593.1 - 5.9e-34 117.5 6.8 7.5e-34 117.2 6.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) RGS PF00615.19 RKP00594.1 - 0.00012 22.4 0.0 0.00032 21.0 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Acetyltransf_1 PF00583.25 RKP00595.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKP00595.1 - 8.8e-08 32.5 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKP00595.1 - 6.2e-07 29.4 0.0 7.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKP00595.1 - 2.8e-06 27.2 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RKP00595.1 - 0.0017 18.5 0.1 0.0022 18.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RKP00595.1 - 0.0032 17.5 0.1 0.0055 16.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RKP00595.1 - 0.0097 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase_3 PF13468.6 RKP00595.1 - 0.037 14.1 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Acetyltransf_6 PF13480.7 RKP00595.1 - 0.087 13.0 1.2 0.25 11.5 0.9 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 RKP00596.1 - 1.9e-90 303.3 16.9 8e-46 156.9 4.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKP00596.1 - 2.5e-69 232.1 0.0 1.6e-33 116.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 RKP00596.1 - 4e-12 46.0 2.7 0.00018 21.0 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RKP00596.1 - 2.5e-08 33.2 0.4 0.0034 16.3 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 RKP00596.1 - 9.4e-07 28.5 1.3 0.004 16.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RKP00596.1 - 3.7e-06 27.3 1.8 0.012 15.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RKP00596.1 - 1.1e-05 24.8 0.1 0.02 14.1 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_16 PF13191.6 RKP00596.1 - 7.7e-05 23.1 6.3 0.29 11.5 0.8 3.8 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 RKP00596.1 - 8.8e-05 22.5 0.3 0.33 10.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 RKP00596.1 - 0.00011 22.0 3.1 0.64 9.7 0.0 3.9 3 2 0 3 3 3 2 AAA domain G-alpha PF00503.20 RKP00596.1 - 0.00048 19.4 0.1 0.66 9.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 RKP00596.1 - 0.001 19.3 0.5 1.4 9.2 0.2 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 RKP00596.1 - 0.0016 18.0 0.2 2.7 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RKP00596.1 - 0.0019 18.1 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 RKP00596.1 - 0.002 17.9 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 RKP00596.1 - 0.0029 16.8 0.0 0.57 9.3 0.0 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 RKP00596.1 - 0.0075 16.4 0.2 0.34 11.0 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 RKP00596.1 - 0.0086 16.1 0.5 7.6 6.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PRK PF00485.18 RKP00596.1 - 0.02 14.7 0.4 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 RKP00596.1 - 0.028 14.6 0.3 6.7 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 RKP00596.1 - 0.032 14.1 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 RKP00596.1 - 0.067 12.9 0.3 4.8 6.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKP00596.1 - 0.076 12.5 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 RKP00596.1 - 0.096 12.0 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 RKP00596.1 - 0.16 11.2 0.2 18 4.4 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 RKP00596.1 - 0.17 12.3 0.2 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 RKP00596.1 - 0.19 12.2 0.1 11 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RKP00596.1 - 0.21 11.8 2.4 22 5.3 0.2 3.1 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 RKP00596.1 - 0.34 10.7 3.5 26 4.5 0.2 3.8 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Ly49 PF08391.10 RKP00597.1 - 0.00023 21.5 0.2 0.00046 20.5 0.2 1.4 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region Tup_N PF08581.10 RKP00597.1 - 0.075 13.3 4.1 0.13 12.6 4.1 1.2 1 0 0 1 1 1 0 Tup N-terminal ATG16 PF08614.11 RKP00597.1 - 0.11 12.7 7.3 0.18 12.0 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ctr PF04145.15 RKP00597.1 - 0.12 13.0 0.3 16 6.1 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF2207 PF09972.9 RKP00598.1 - 0.1 11.4 0.3 0.15 10.8 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4307 PF14155.6 RKP00598.1 - 0.14 12.0 0.1 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) EF1G PF00647.19 RKP00599.1 - 7.9e-49 164.2 0.3 1.5e-48 163.3 0.3 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 RKP00599.1 - 3e-17 62.6 0.1 1.3e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RKP00599.1 - 1.9e-13 50.5 0.0 4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RKP00599.1 - 2.8e-08 34.0 0.0 6.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RKP00599.1 - 3.2e-08 33.5 0.6 1.1e-07 31.7 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RKP00599.1 - 2.2e-07 31.0 0.0 1.3e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RKP00599.1 - 3.8e-05 23.9 0.0 8.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 RKP00599.1 - 0.038 14.4 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PseudoU_synth_2 PF00849.22 RKP00600.1 - 4.7e-30 104.8 0.0 6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase ubiquitin PF00240.23 RKP00601.1 - 3.2e-34 116.5 1.7 4.9e-34 115.9 0.9 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 RKP00601.1 - 5.9e-24 84.0 3.5 1.2e-23 82.9 3.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 RKP00601.1 - 4.9e-16 58.3 0.9 8.8e-16 57.5 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RKP00601.1 - 8.6e-06 26.1 0.3 5.2e-05 23.6 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RKP00601.1 - 0.00034 20.7 0.6 0.001 19.1 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RKP00601.1 - 0.0037 17.2 0.1 0.0053 16.7 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 RKP00601.1 - 0.0037 17.8 0.5 0.0053 17.3 0.5 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 RKP00601.1 - 0.0039 17.5 0.5 0.0072 16.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 RKP00601.1 - 0.014 15.4 1.3 3.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 RKP00601.1 - 0.014 15.6 0.3 0.025 14.8 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sde2_N_Ubi PF13019.6 RKP00601.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Plexin_cytopl PF08337.12 RKP00601.1 - 0.86 8.2 2.8 6.9 5.2 0.4 2.2 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Pkinase PF00069.25 RKP00604.1 - 5.4e-54 183.3 0.0 4.4e-53 180.3 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00604.1 - 3.4e-28 98.6 0.0 5.8e-16 58.6 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 RKP00604.1 - 5.1e-05 22.7 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 RKP00604.1 - 0.00092 18.2 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP00604.1 - 0.0035 16.7 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RKP00604.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 RKP00604.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase dsrm PF00035.26 RKP00605.1 - 3e-08 34.3 0.4 0.00043 20.9 0.1 4.2 4 0 0 4 4 4 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 RKP00605.1 - 1.2e-05 25.5 3.9 0.00043 20.5 0.1 4.3 4 1 0 4 4 4 1 double strand RNA binding domain from DEAD END PROTEIN 1 Dishevelled PF02377.15 RKP00606.1 - 0.26 11.7 5.6 0.34 11.4 5.6 1.2 1 0 0 1 1 1 0 Dishevelled specific domain zf-C2H2 PF00096.26 RKP00607.1 - 2.4e-15 56.0 12.9 0.00018 21.8 1.5 3.5 2 1 1 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP00607.1 - 2.1e-11 43.7 11.6 0.0015 19.2 0.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP00607.1 - 1.1e-09 38.3 14.5 4.2e-05 23.8 1.3 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 RKP00607.1 - 2.1e-08 34.3 2.3 0.054 13.9 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RKP00607.1 - 7.8e-08 32.4 3.4 0.14 12.5 0.0 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP00607.1 - 0.00036 20.4 8.5 0.0082 16.1 0.1 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 RKP00607.1 - 0.0051 17.4 6.5 3 8.5 0.2 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 RKP00607.1 - 0.0053 16.5 10.6 0.49 10.2 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RKP00607.1 - 0.0094 16.2 3.3 0.013 15.8 3.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 RKP00607.1 - 0.068 13.6 8.8 0.21 12.1 0.1 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 RKP00607.1 - 0.2 11.5 3.6 5.6 6.9 0.2 2.6 1 1 1 2 2 2 0 GAGA factor zf_ZIC PF18366.1 RKP00607.1 - 0.42 10.8 5.3 27 4.9 0.6 3.4 1 1 2 4 4 4 0 Zic proteins zinc finger domain zf-BED PF02892.15 RKP00607.1 - 1.5 8.9 8.2 1.5 8.9 1.6 2.8 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_11 PF16622.5 RKP00607.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.3 4 1 0 4 4 4 0 zinc-finger C2H2-type FCH PF00611.23 RKP00608.1 - 1.6e-14 53.9 0.2 1.6e-14 53.9 0.2 2.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 RKP00608.1 - 2e-12 46.5 0.0 3.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP00608.1 - 1.9e-10 40.5 0.0 3.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP00608.1 - 5.5e-09 35.6 0.0 1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SPATA1_C PF15743.5 RKP00608.1 - 0.0088 16.1 4.0 0.019 15.1 4.0 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus TSP_NTD PF17804.1 RKP00608.1 - 0.27 11.5 2.2 0.45 10.8 2.2 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Glycolytic PF00274.19 RKP00609.1 - 1.1e-174 580.1 0.0 1.3e-174 579.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Bromodomain PF00439.25 RKP00610.1 - 2.1e-12 47.0 0.0 4.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Planc_extracel PF07595.12 RKP00611.1 - 0.002 17.8 0.5 0.0062 16.2 0.5 1.8 1 0 0 1 1 1 1 Planctomycete extracellular Cep57_MT_bd PF06657.13 RKP00611.1 - 0.012 16.1 0.2 0.033 14.6 0.2 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 PI3_PI4_kinase PF00454.27 RKP00612.1 - 1.9e-47 162.2 0.0 2.5e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RKP00612.1 - 2.7e-11 43.1 0.1 5e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 FATC domain Pkinase PF00069.25 RKP00613.1 - 4.1e-53 180.4 0.0 4.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00613.1 - 7.9e-22 77.8 0.0 9.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00613.1 - 5e-05 22.8 0.0 7.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP00613.1 - 6.6e-05 22.3 0.5 9.1e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP00613.1 - 0.00036 20.5 0.7 0.1 12.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RKP00613.1 - 0.015 14.9 0.1 0.022 14.4 0.1 1.3 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RKP00613.1 - 0.029 13.2 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L31 PF01197.18 RKP00614.1 - 2.9e-05 24.2 0.0 4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 Ribosomal_S7 PF00177.21 RKP00615.1 - 6.9e-29 100.4 4.5 8.3e-29 100.2 4.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e XRN_N PF03159.18 RKP00615.1 - 0.0023 17.4 0.1 0.0027 17.2 0.1 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Complex1_30kDa PF00329.19 RKP00616.1 - 1.4e-47 161.3 0.0 1.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Glyco_hydro_1 PF00232.18 RKP00617.1 - 2.4e-118 395.4 0.0 2.9e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 ACOX PF01756.19 RKP00618.1 - 2.6e-37 128.1 0.0 5.2e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 RKP00618.1 - 7e-18 64.6 1.0 1.7e-17 63.4 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 RKP00618.1 - 4e-13 50.0 0.0 1e-12 48.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Rrn6 PF10214.9 RKP00619.1 - 0.013 14.1 0.6 0.017 13.7 0.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FtsK_4TM PF13491.6 RKP00619.1 - 0.1 12.3 6.2 0.14 11.8 2.5 2.2 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE Med22 PF06179.12 RKP00620.1 - 9e-12 45.1 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SUIM_assoc PF16619.5 RKP00621.1 - 0.0066 16.5 1.5 0.011 15.7 1.5 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Atg14 PF10186.9 RKP00621.1 - 0.045 12.8 1.5 0.059 12.5 1.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OEP PF02321.18 RKP00621.1 - 0.11 12.3 9.6 0.19 11.5 9.6 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein ZapB PF06005.12 RKP00621.1 - 0.13 12.7 5.3 0.62 10.6 0.3 2.2 2 0 0 2 2 2 0 Cell division protein ZapB RRM_1 PF00076.22 RKP00622.1 - 2.4e-19 68.9 0.0 2.9e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP00622.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif ETF_QO PF05187.13 RKP00623.1 - 4.1e-43 145.8 0.0 7.4e-43 144.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 RKP00623.1 - 2.2e-08 33.6 0.6 0.0002 20.6 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 RKP00623.1 - 2.7e-06 27.2 0.0 0.0005 19.8 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 RKP00623.1 - 8.6e-06 25.2 0.0 0.0003 20.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 RKP00623.1 - 1.8e-05 24.9 0.0 5.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RKP00623.1 - 8.2e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RKP00623.1 - 0.0004 19.2 0.6 0.00066 18.5 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 RKP00623.1 - 0.00043 20.3 0.4 0.00099 19.1 0.2 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 RKP00623.1 - 0.0012 18.1 0.2 0.003 16.8 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.7 RKP00623.1 - 0.0014 19.2 1.0 0.0032 18.0 1.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 RKP00623.1 - 0.0022 17.3 0.9 0.0032 16.8 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RKP00623.1 - 0.0026 16.9 0.4 0.0042 16.2 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 RKP00623.1 - 0.0029 18.1 0.1 1.6 9.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RKP00623.1 - 0.065 12.6 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_10 PF13237.6 RKP00623.1 - 0.16 12.1 0.9 0.36 11.0 0.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 RKP00623.1 - 0.25 10.4 0.4 0.39 9.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-MYND PF01753.18 RKP00624.1 - 0.0016 18.5 4.5 0.003 17.6 4.5 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 RKP00624.1 - 0.083 13.0 1.1 0.16 12.1 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Histone PF00125.24 RKP00625.1 - 9.2e-49 165.1 2.9 1e-48 165.0 2.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 RKP00625.1 - 3.5e-05 24.4 1.2 4.1e-05 24.2 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 RKP00625.1 - 7.1e-05 23.1 0.1 0.0001 22.6 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RKP00625.1 - 9.9e-05 22.4 0.2 9.9e-05 22.4 0.2 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RKP00625.1 - 0.0062 16.8 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RKP00625.1 - 0.044 13.9 0.2 0.079 13.0 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RKP00625.1 - 0.094 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 RKP00626.1 - 1.1e-08 35.1 0.1 1.3e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 RKP00626.1 - 5.5e-05 23.5 0.4 6.3e-05 23.3 0.4 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKP00626.1 - 6e-05 23.3 0.1 9.8e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 RKP00626.1 - 0.00026 21.1 0.1 0.00035 20.7 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 RKP00626.1 - 0.00062 20.1 0.1 0.00079 19.8 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 RKP00626.1 - 0.0033 17.4 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 RKP00626.1 - 0.028 14.5 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Meckelin PF09773.9 RKP00628.1 - 0.22 9.6 0.1 0.28 9.2 0.1 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Myb_DNA-bind_3 PF12776.7 RKP00629.1 - 4.8e-16 59.5 0.1 7.1e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 RKP00629.1 - 3.7e-05 24.0 0.0 5.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 RKP00629.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain EPL1 PF10513.9 RKP00630.1 - 0.0025 18.2 2.6 0.0025 18.2 2.6 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 RKP00630.1 - 0.091 11.7 56.6 0.089 11.7 32.7 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Cellulose_synt PF03552.14 RKP00630.1 - 0.18 10.3 0.8 0.24 9.9 0.8 1.1 1 0 0 1 1 1 0 Cellulose synthase YjbH PF06082.11 RKP00630.1 - 0.65 8.7 8.7 1.1 8.0 8.7 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF702 PF05142.12 RKP00630.1 - 1.9 9.0 15.2 0.27 11.7 7.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) EOS1 PF12326.8 RKP00630.1 - 5.3 6.9 11.0 0.058 13.3 2.9 1.7 2 0 0 2 2 2 0 N-glycosylation protein Spt20 PF12090.8 RKP00630.1 - 5.8 6.5 52.4 0.88 9.1 7.6 2.4 2 0 0 2 2 2 0 Spt20 family CSG2 PF16965.5 RKP00630.1 - 5.8 5.7 6.2 9.8 5.0 6.2 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator MCU PF04678.13 RKP00630.1 - 6.2 6.9 10.5 0.4 10.8 4.0 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CPSF100_C PF13299.6 RKP00630.1 - 6.6 6.9 13.9 0.54 10.4 6.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_23 PF13476.6 RKP00630.1 - 8.1 6.9 12.5 14 6.1 12.5 1.4 1 1 0 1 1 1 0 AAA domain MitMem_reg PF13012.6 RKP00631.1 - 2.3e-11 44.1 0.1 3.9e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RKP00631.1 - 2.6e-07 30.6 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1576 PF07613.11 RKP00631.1 - 0.17 11.4 0.0 1.8 8.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1576) DUF4874 PF16173.5 RKP00632.1 - 1.7e-06 27.8 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) PRCC PF10253.9 RKP00632.1 - 0.067 14.0 4.9 0.1 13.4 4.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4832 PF16116.5 RKP00632.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) Aminotran_1_2 PF00155.21 RKP00634.1 - 6.9e-55 186.7 0.0 8.3e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RKP00634.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RKP00634.1 - 0.0073 15.7 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RKP00634.1 - 0.0095 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RKP00634.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aa_trans PF01490.18 RKP00635.1 - 4.4e-78 262.8 33.4 5.1e-78 262.6 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PPR_2 PF13041.6 RKP00636.1 - 0.067 13.4 0.1 0.36 11.1 0.0 2.1 1 1 1 2 2 2 0 PPR repeat family PPR PF01535.20 RKP00636.1 - 0.072 13.4 0.1 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 PPR repeat GATase PF00117.28 RKP00637.1 - 7.6e-13 48.7 0.0 8.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKP00637.1 - 0.0014 18.4 0.3 0.0035 17.1 0.3 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 RKP00637.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PWWP PF00855.17 RKP00639.1 - 1.8e-18 66.7 0.3 4.1e-18 65.6 0.3 1.6 1 0 0 1 1 1 1 PWWP domain CENP-B_dimeris PF09026.10 RKP00639.1 - 0.12 12.8 4.8 0.35 11.3 4.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PGA2 PF07543.12 RKP00639.1 - 0.42 10.6 5.2 1.4 8.9 5.2 1.9 1 0 0 1 1 1 0 Protein trafficking PGA2 PBP1_TM PF14812.6 RKP00639.1 - 3.4 8.1 11.6 0.9 10.0 7.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAP_GLY PF01302.25 RKP00640.1 - 4.4e-15 55.4 0.0 8.8e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Lebercilin PF15619.6 RKP00640.1 - 0.019 14.7 22.7 0.024 14.3 1.3 3.3 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HCMV_UL139 PF12507.8 RKP00640.1 - 0.16 12.3 1.2 0.68 10.3 1.2 2.0 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF1664 PF07889.12 RKP00640.1 - 1 9.4 5.3 3.8 7.6 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ring_hydroxyl_A PF00848.19 RKP00640.1 - 1.5 8.8 8.8 6.9 6.6 1.7 4.0 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) SHE3 PF17078.5 RKP00640.1 - 3 7.5 9.2 2.8 7.6 3.1 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Troponin PF00992.20 RKP00640.1 - 3.3 8.0 11.5 2 8.8 0.5 3.1 3 0 0 3 3 3 0 Troponin YabA PF06156.13 RKP00640.1 - 3.4 8.4 9.2 8.6 7.1 1.4 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin_2 PF01920.20 RKP00640.1 - 8.7 6.4 8.2 21 5.1 1.4 3.0 2 0 0 2 2 2 0 Prefoldin subunit CDP-OH_P_transf PF01066.21 RKP00641.1 - 6.4e-18 65.3 0.5 6.4e-18 65.3 0.5 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4752 PF15944.5 RKP00641.1 - 0.059 13.4 1.2 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) TraD PF06412.11 RKP00641.1 - 0.12 12.2 0.8 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Conjugal transfer protein TraD zf-CCHC PF00098.23 RKP00643.1 - 0.017 15.2 13.6 0.038 14.1 0.3 3.4 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 RKP00643.1 - 0.17 11.8 16.8 0.4 10.7 0.1 4.0 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 RKP00643.1 - 0.41 10.4 18.8 0.092 12.5 0.5 4.1 4 0 0 4 4 4 0 Zinc knuckle SGP PF17228.2 RKP00643.1 - 0.92 10.4 6.7 2.2 9.2 6.7 1.6 1 0 0 1 1 1 0 Sulphur globule protein Zw10 PF06248.13 RKP00644.1 - 9.8e-07 27.7 0.0 3.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 bZIP_1 PF00170.21 RKP00645.1 - 8.5e-13 48.2 1.4 8.5e-13 48.2 1.4 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RKP00645.1 - 2.9e-11 43.3 3.3 2.9e-11 43.3 3.3 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 RKP00645.1 - 0.0021 18.5 2.0 0.0021 18.5 2.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor Nucleo_P87 PF07267.11 RKP00645.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAP_N PF01213.19 RKP00646.1 - 3.2 7.2 7.5 5.7 6.3 7.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CBS PF00571.28 RKP00647.1 - 1.8e-12 47.5 1.9 0.0041 17.5 0.1 4.4 4 0 0 4 4 4 4 CBS domain DUF2733 PF10813.8 RKP00647.1 - 0.025 14.3 0.5 0.069 12.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) HTH_9 PF08221.11 RKP00647.1 - 0.29 11.2 1.3 0.87 9.7 0.3 2.2 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Adaptin_N PF01602.20 RKP00648.1 - 1.2e-94 317.8 8.7 1.4e-94 317.5 8.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 RKP00648.1 - 9.6e-41 139.4 0.0 4.1e-40 137.4 0.0 2.1 1 1 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 RKP00648.1 - 2.1e-25 89.1 0.0 4.8e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 RKP00648.1 - 4.5e-20 71.8 5.5 1.7e-10 41.1 0.2 6.0 4 2 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 RKP00648.1 - 1.6e-10 41.3 8.3 0.00013 22.1 0.7 4.2 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RKP00648.1 - 1.2e-06 28.2 12.1 2.1 8.8 0.1 8.4 9 0 0 9 9 9 3 HEAT repeat HEAT_PBS PF03130.16 RKP00648.1 - 0.005 17.4 1.8 1.9 9.4 0.6 4.1 2 0 0 2 2 2 1 PBS lyase HEAT-like repeat SPG48 PF14764.6 RKP00648.1 - 0.022 15.2 0.2 1.8 9.0 0.1 3.0 1 1 1 2 2 2 0 AP-5 complex subunit, vesicle trafficking DUF3385 PF11865.8 RKP00648.1 - 0.13 12.1 2.6 3 7.7 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 RKP00648.1 - 0.19 12.3 13.1 0.39 11.3 2.6 5.4 5 2 1 6 6 6 0 HEAT-like repeat RRN3 PF05327.11 RKP00649.1 - 1.4e-76 258.2 0.4 2e-76 257.7 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 ATP-synt_F PF01990.17 RKP00650.1 - 6e-31 106.6 0.1 6.9e-31 106.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Dynamin_N PF00350.23 RKP00651.1 - 2.3e-42 144.9 0.0 3.6e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 RKP00651.1 - 5.9e-10 38.8 0.0 2.6e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 RKP00651.1 - 1.8e-06 28.0 0.0 4.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 RKP00651.1 - 0.013 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 RKP00651.1 - 0.1 12.8 1.1 0.28 11.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 RKP00651.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 RKP00651.1 - 0.21 11.8 0.0 0.56 10.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RKP00651.1 - 0.47 10.8 2.6 1.2 9.4 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain Cullin_binding PF03556.15 RKP00652.1 - 2.3e-30 105.5 0.0 3.1e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 RKP00652.1 - 0.0016 18.2 0.1 0.0047 16.7 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain UCR_hinge PF02320.16 RKP00653.1 - 3.8e-23 81.5 4.8 4e-23 81.4 4.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein LSM PF01423.22 RKP00654.1 - 1.5e-12 47.0 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain YhzD PF14120.6 RKP00654.1 - 0.003 17.6 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 YhzD-like protein IKI3 PF04762.12 RKP00655.1 - 4.4e-188 627.3 0.0 3.8e-71 240.3 0.0 3.2 2 1 1 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 RKP00655.1 - 0.002 18.4 0.1 0.43 10.9 0.0 4.1 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Se-cys_synth_N PF12390.8 RKP00655.1 - 0.17 12.1 3.2 1.5 9.1 0.3 3.8 2 1 0 2 2 2 0 Selenocysteine synthase N terminal DS PF01916.17 RKP00656.1 - 3.5e-126 420.3 0.0 4.3e-126 420.0 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Exo_endo_phos PF03372.23 RKP00657.1 - 8.9e-12 45.0 0.1 1.1e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_primase_lrg PF04104.14 RKP00659.1 - 3.4e-82 275.8 0.0 4.8e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pro_isomerase PF00160.21 RKP00660.1 - 1.3e-48 165.2 0.0 1.5e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_N PF00134.23 RKP00661.1 - 0.0045 16.7 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain Metallophos PF00149.28 RKP00663.1 - 2e-13 51.3 0.5 2.4e-13 51.0 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 RKP00663.1 - 2.5e-05 22.8 0.0 0.00015 20.2 0.0 2.0 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase ABA_GPCR PF12430.8 RKP00664.1 - 1.1e-38 132.8 11.6 1.1e-38 132.8 11.6 2.8 3 1 0 3 3 3 2 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 RKP00664.1 - 6e-23 80.7 0.3 2e-22 79.0 0.1 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal YfzA PF14118.6 RKP00664.1 - 0.3 11.5 7.2 7.5 7.0 0.1 3.6 3 0 0 3 3 3 0 YfzA-like protein Ras PF00071.22 RKP00665.1 - 4.3e-56 189.0 0.2 5e-56 188.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP00665.1 - 6.3e-21 74.8 0.0 8.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP00665.1 - 7.5e-09 35.3 0.2 8.6e-09 35.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKP00665.1 - 2.8e-05 23.8 0.5 7.1e-05 22.4 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKP00665.1 - 0.00031 20.8 0.1 0.00049 20.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKP00665.1 - 0.00039 20.3 1.0 0.38 10.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 RKP00665.1 - 0.031 13.5 0.1 4.3 6.4 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 RKP00665.1 - 0.09 12.5 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain SURF1 PF02104.15 RKP00670.1 - 9.4e-45 153.0 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Cellulase PF00150.18 RKP00671.1 - 2.7e-16 59.9 0.0 2.9e-10 40.1 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 RKP00671.1 - 1.8e-07 31.6 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 RKP00671.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF866 PF05907.13 RKP00672.1 - 6.7e-41 139.8 0.0 7.4e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn-C2H2_12 PF18112.1 RKP00672.1 - 0.13 12.7 1.3 0.24 11.9 0.3 1.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 RKP00672.1 - 0.25 11.9 1.2 20 5.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain cNMP_binding PF00027.29 RKP00673.1 - 1.1e-11 44.6 0.0 3.5e-05 23.8 0.0 4.0 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain LKAAEAR PF15478.6 RKP00674.1 - 0.0012 19.1 12.7 0.0019 18.5 12.3 1.6 1 1 0 1 1 1 1 Family of unknown function with LKAAEAR motif Oxidored-like PF09791.9 RKP00675.1 - 9.1e-17 60.5 3.9 2e-16 59.4 3.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal JUPITER PF17054.5 RKP00675.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter DUF5522 PF17653.1 RKP00675.1 - 0.073 13.0 2.8 0.14 12.1 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Hpt PF01627.23 RKP00675.1 - 0.29 11.4 2.5 6.8 7.0 2.7 2.3 2 0 0 2 2 2 0 Hpt domain Cornifin PF02389.15 RKP00679.1 - 0.0021 18.3 5.4 0.0021 18.3 5.4 4.6 3 1 1 4 4 4 3 Cornifin (SPRR) family Cullin PF00888.22 RKP00680.1 - 1.3e-105 354.4 0.0 1.7e-105 353.9 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RKP00680.1 - 1.4e-18 66.6 0.0 2.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain Arm PF00514.23 RKP00681.1 - 0.021 14.9 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat APS_kinase PF01583.20 RKP00681.1 - 0.049 13.5 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP PF05804.12 RKP00681.1 - 0.06 11.5 0.2 0.088 10.9 0.2 1.3 1 1 0 1 1 1 0 Kinesin-associated protein (KAP) PX PF00787.24 RKP00683.1 - 3.5e-06 27.0 0.0 8e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 PX domain DUF4685 PF15737.5 RKP00683.1 - 4.9 7.6 5.8 15 6.0 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4685) F-box-like PF12937.7 RKP00684.1 - 1.8e-06 27.8 0.2 7.3e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like PP2 PF14299.6 RKP00684.1 - 0.00022 21.3 0.0 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 RKP00684.1 - 0.0031 17.3 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Rubi_NSP_C PF12601.8 RKP00684.1 - 0.0095 16.0 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 1 Rubivirus non-structural protein IATP PF04568.12 RKP00686.1 - 2.9e-07 30.8 4.7 0.014 15.8 0.3 3.1 1 1 2 3 3 3 2 Mitochondrial ATPase inhibitor, IATP Cas_Cmr3 PF09700.10 RKP00686.1 - 0.0035 16.8 0.2 0.004 16.6 0.2 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr3) DUF2185 PF09951.9 RKP00686.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DUF1476 PF07345.11 RKP00686.1 - 0.38 11.1 4.8 0.75 10.2 1.7 2.2 2 1 0 2 2 2 0 ATPase inhibitor subunit zeta PHD PF00628.29 RKP00688.1 - 3.3e-11 42.9 9.0 3.9e-06 26.7 7.7 2.4 2 0 0 2 2 2 2 PHD-finger DHHA1 PF02272.19 RKP00688.1 - 0.13 12.6 0.3 0.42 11.0 0.3 1.8 1 0 0 1 1 1 0 DHHA1 domain PHD_2 PF13831.6 RKP00688.1 - 0.19 11.3 4.8 0.77 9.4 2.6 2.5 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 RKP00688.1 - 1.6 8.7 9.2 2.2 8.2 3.5 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 RKP00688.1 - 3 8.2 7.3 0.82 10.0 3.7 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain PWWP PF00855.17 RKP00689.1 - 6e-05 23.4 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 PWWP domain Glyco_transf_34 PF05637.12 RKP00690.1 - 1.2e-23 84.1 0.4 4.6e-15 56.0 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family PHD PF00628.29 RKP00691.1 - 2.5e-07 30.5 6.5 3e-07 30.2 6.5 1.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKP00691.1 - 8e-05 22.1 1.1 0.00013 21.4 1.1 1.5 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RKP00691.1 - 0.0015 18.7 2.5 0.0015 18.7 2.5 1.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 RKP00691.1 - 0.099 12.8 4.6 0.055 13.6 3.5 1.2 1 1 0 1 1 1 0 PHD-zinc-finger like domain WD40 PF00400.32 RKP00692.1 - 2.3e-21 75.7 6.3 8.8e-05 23.2 0.1 6.7 7 1 0 7 7 7 4 WD domain, G-beta repeat Katanin_con80 PF13925.6 RKP00692.1 - 2.9e-17 63.2 0.0 4.6e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 RKP00692.1 - 3.7e-09 36.8 0.0 0.36 11.2 0.0 4.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RKP00692.1 - 0.072 11.6 0.0 0.73 8.3 0.1 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 RKP00692.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RKP00692.1 - 0.19 10.6 0.1 17 4.2 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RKP00692.1 - 0.26 9.6 0.0 1.5 7.0 0.0 1.8 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3844 PF12955.7 RKP00693.1 - 7.1e-21 74.3 1.3 1.1e-20 73.8 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) WD40 PF00400.32 RKP00694.1 - 1.7e-39 133.1 9.2 6.7e-07 29.9 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00694.1 - 6.7e-09 35.9 0.1 0.31 11.4 0.1 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP00694.1 - 0.0029 16.6 0.0 3.1 6.6 0.0 3.2 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BAH PF01426.18 RKP00695.1 - 8.1e-14 51.5 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 RKP00695.1 - 9.6e-08 32.2 0.2 9.6e-08 32.2 0.2 4.7 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RKP00695.1 - 4.6e-05 23.6 0.2 0.0033 17.6 0.0 5.5 5 1 0 5 5 4 2 PHD-like zinc-binding domain zf-ribbon_3 PF13248.6 RKP00695.1 - 7.4e-05 22.0 5.0 0.0005 19.4 0.7 2.9 2 0 0 2 2 2 1 zinc-ribbon domain PHD_2 PF13831.6 RKP00695.1 - 0.00022 20.7 2.0 0.00022 20.7 2.0 4.5 4 0 0 4 4 4 1 PHD-finger PHD_4 PF16866.5 RKP00695.1 - 0.0003 20.8 0.5 0.0003 20.8 0.5 4.4 4 0 0 4 4 4 1 PHD-finger Prok-RING_1 PF14446.6 RKP00695.1 - 0.0074 16.2 6.5 0.0074 16.2 6.5 3.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 RKP00695.1 - 0.008 16.0 0.2 0.008 16.0 0.2 4.9 5 0 0 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) CBFB_NFYA PF02045.15 RKP00695.1 - 3.1 8.5 5.9 11 6.8 5.9 2.0 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PHD PF00628.29 RKP00695.1 - 5 7.1 39.8 0.041 13.8 10.0 5.9 6 0 0 6 6 6 0 PHD-finger UPF0547 PF10571.9 RKP00695.1 - 5.5 7.2 15.3 0.06 13.4 2.5 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 AvrPphF-ORF-2 PF09143.10 RKP00696.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.4 1 0 0 1 1 1 0 AvrPphF-ORF-2 PI3_PI4_kinase PF00454.27 RKP00697.1 - 7.1e-22 78.4 0.0 7.5e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MutS_V PF00488.21 RKP00698.1 - 6.8e-67 225.1 0.1 1.5e-66 224.0 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKP00698.1 - 2.9e-18 66.8 0.1 5e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 RKP00698.1 - 8.7e-15 55.0 0.0 1.7e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain I Thiol_cytolysin PF01289.19 RKP00698.1 - 0.0012 17.8 0.1 0.0019 17.2 0.1 1.1 1 0 0 1 1 1 1 Thiol-activated cytolysin AAA_27 PF13514.6 RKP00698.1 - 0.03 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 RKP00699.1 - 7.5e-15 55.1 2.7 0.00042 21.0 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT_2 PF13646.6 RKP00699.1 - 1.9e-05 25.0 5.8 5.3e-05 23.5 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 RKP00699.1 - 0.13 12.5 0.4 0.61 10.5 0.4 2.2 1 0 0 1 1 1 0 HEAT repeat Suf PF05843.14 RKP00700.1 - 5.9e-38 131.5 0.1 5.9e-38 131.5 0.1 3.6 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 RKP00700.1 - 5.2e-10 39.0 1.2 3.5e-09 36.2 0.0 2.7 2 2 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 RKP00700.1 - 0.12 13.2 12.3 16 6.6 0.0 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat Mob_Pre PF01076.19 RKP00700.1 - 0.19 11.5 1.1 0.37 10.6 0.2 1.8 2 0 0 2 2 2 0 Plasmid recombination enzyme PP28 PF10252.9 RKP00700.1 - 0.57 10.7 4.7 5.1 7.6 0.1 3.0 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Mad3_BUB1_I PF08311.12 RKP00700.1 - 7.4 6.6 8.9 2.3 8.2 0.0 4.0 5 2 0 5 5 5 0 Mad3/BUB1 homology region 1 RRM_1 PF00076.22 RKP00701.1 - 0.011 15.5 0.2 4.6 7.1 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PilZ PF07238.14 RKP00701.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 PilZ domain DUF1175 PF06672.11 RKP00701.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) DEK_C PF08766.11 RKP00702.1 - 9.6e-09 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain HEM4 PF02602.15 RKP00703.1 - 9.4e-29 100.4 4.6 1.1e-28 100.2 4.6 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF5496 PF17600.2 RKP00703.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5496) CLP1_P PF16575.5 RKP00704.1 - 7.2e-32 110.7 0.0 7.9e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 RKP00704.1 - 0.0062 16.6 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SecE PF00584.20 RKP00705.1 - 1.6e-13 50.4 0.0 1.9e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SHNi-TPR PF10516.9 RKP00706.1 - 9.9e-11 40.9 0.1 2.2e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.6 RKP00706.1 - 5.8e-10 39.3 9.6 4.1e-07 30.2 2.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKP00706.1 - 0.0006 19.7 7.4 0.48 10.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF688 PF05097.12 RKP00706.1 - 0.27 10.4 4.4 0.47 9.6 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF688) TPR_6 PF13174.6 RKP00706.1 - 0.28 11.9 3.0 89 4.1 0.1 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NOA36 PF06524.12 RKP00706.1 - 0.68 9.2 10.8 1.4 8.2 10.8 1.4 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 RKP00706.1 - 0.81 9.2 4.9 1.4 8.5 4.9 1.3 1 0 0 1 1 1 0 PPP4R2 CENP-B_dimeris PF09026.10 RKP00706.1 - 1.2 9.5 11.1 3.5 8.1 11.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RKP00706.1 - 6.5 6.4 14.7 0.21 11.3 7.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FA_desaturase PF00487.24 RKP00707.1 - 1.2e-36 126.9 23.6 2e-36 126.1 23.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 RKP00707.1 - 2.5e-12 46.8 0.0 5.6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ORC3_N PF07034.11 RKP00708.1 - 8.4e-35 120.4 0.0 1.3e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 RKP00708.1 - 2.2e-26 92.6 1.5 5.5e-14 52.4 0.0 2.9 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Luteo_P1-P2 PF08467.10 RKP00710.1 - 0.095 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase PWI PF01480.17 RKP00710.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 PWI domain NOA36 PF06524.12 RKP00711.1 - 2.7 7.2 4.7 4.9 6.4 4.7 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 RKP00711.1 - 5.3 6.7 18.4 0.24 11.1 6.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cnd3 PF12719.7 RKP00712.1 - 2.8e-37 128.5 0.0 9.2e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 RKP00712.1 - 0.0012 18.9 9.7 1.8 9.1 0.1 5.7 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 RKP00712.1 - 0.0058 16.7 0.9 4.5 7.3 0.1 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cbl_N PF02262.16 RKP00712.1 - 0.04 13.9 0.1 0.13 12.2 0.1 1.9 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 TFCD_C PF12612.8 RKP00712.1 - 0.057 13.2 0.2 0.59 9.9 0.1 2.7 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Kinesin PF00225.23 RKP00714.1 - 1.4e-101 339.8 1.4 1.6e-101 339.6 1.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP00714.1 - 2e-20 73.2 0.1 3.6e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 RKP00714.1 - 0.12 12.7 0.4 0.25 11.6 0.4 1.7 1 1 0 1 1 1 0 AAA domain Fip1 PF05182.13 RKP00715.1 - 6.1e-20 70.5 0.3 9.3e-20 69.9 0.3 1.3 1 0 0 1 1 1 1 Fip1 motif CBF PF03914.17 RKP00716.1 - 9.9e-22 77.8 0.1 1.2e-21 77.5 0.1 1.1 1 0 0 1 1 1 1 CBF/Mak21 family Ribosomal_L50 PF10501.9 RKP00717.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal subunit 39S Septin PF00735.18 RKP00718.1 - 9.7e-94 313.8 0.0 1.5e-93 313.2 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RKP00718.1 - 6.2e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RKP00718.1 - 3e-07 30.0 0.4 8.1e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 RKP00718.1 - 7.5e-07 29.2 0.1 2.6e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 RKP00718.1 - 0.00026 21.1 6.1 0.045 13.8 0.1 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 RKP00718.1 - 0.00031 20.3 0.1 0.006 16.1 0.0 2.5 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 RKP00718.1 - 0.0016 18.7 3.4 0.0059 16.9 0.0 3.0 2 2 0 2 2 2 1 AAA domain FeoB_N PF02421.18 RKP00718.1 - 0.0027 17.2 0.0 0.0069 15.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Pox_A32 PF04665.12 RKP00718.1 - 0.0045 16.5 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_16 PF13191.6 RKP00718.1 - 0.0046 17.4 0.7 0.036 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 RKP00718.1 - 0.0047 16.3 2.6 0.069 12.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family IIGP PF05049.13 RKP00718.1 - 0.01 15.0 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 RKP00718.1 - 0.028 14.9 0.1 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 RKP00718.1 - 0.049 13.8 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TPR_5 PF12688.7 RKP00718.1 - 0.05 13.9 3.0 0.092 13.0 3.0 1.5 1 1 0 1 1 1 0 Tetratrico peptide repeat NACHT PF05729.12 RKP00718.1 - 0.071 13.0 0.2 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 RKP00718.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RKP00718.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3726 PF12525.8 RKP00718.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) DegS PF05384.11 RKP00718.1 - 3.2 7.2 11.2 4.5 6.8 8.9 2.1 2 0 0 2 2 2 0 Sensor protein DegS DAP3 PF10236.9 RKP00719.1 - 5.1e-26 91.6 0.0 8.5e-20 71.1 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 RKP00719.1 - 0.00038 20.9 6.0 0.00046 20.6 3.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 RKP00719.1 - 0.0021 17.8 3.0 0.0059 16.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RKP00719.1 - 0.018 14.8 0.6 0.063 13.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 RKP00719.1 - 0.05 13.9 0.0 0.21 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RKP00719.1 - 0.06 13.3 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 RKP00719.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 RKP00719.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ANTH PF07651.16 RKP00720.1 - 2.6e-64 216.9 0.0 2.6e-64 216.9 0.0 3.3 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 RKP00720.1 - 2e-48 164.5 11.9 2e-48 164.5 11.9 5.3 3 2 2 6 6 6 1 I/LWEQ domain Aha1_N PF09229.11 RKP00722.1 - 6.8e-31 107.3 0.0 1.2e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 RKP00722.1 - 2.1e-11 44.1 0.3 1e-10 41.9 0.3 2.1 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 RKP00722.1 - 6.9e-05 23.1 2.8 0.00022 21.5 2.8 1.9 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Dehydrin PF00257.19 RKP00723.1 - 0.15 12.6 0.1 0.15 12.6 0.1 4.6 6 1 0 6 6 6 0 Dehydrin RNA_pol_Rpc4 PF05132.14 RKP00723.1 - 0.46 10.9 3.2 1 9.8 0.2 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 PGAP1 PF07819.13 RKP00724.1 - 1e-42 146.5 0.0 2.1e-42 145.4 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 RKP00724.1 - 0.0037 16.9 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 RKP00724.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 RKP00724.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 RKP00724.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 RKP00724.1 - 0.043 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PIN_4 PF13638.6 RKP00726.1 - 3.9e-17 62.8 0.0 6.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 PIN domain ABC2_membrane PF01061.24 RKP00727.1 - 7.9e-64 214.9 44.0 3.6e-32 111.5 14.9 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 RKP00727.1 - 9.9e-33 113.6 0.0 1.4e-16 61.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 RKP00727.1 - 1.1e-23 82.9 7.2 4.9e-20 71.2 0.0 3.5 4 0 0 4 4 3 2 CDR ABC transporter AAA_16 PF13191.6 RKP00727.1 - 4.4e-07 30.4 1.7 0.0089 16.4 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 RKP00727.1 - 6.1e-07 29.1 0.2 0.00057 19.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 RKP00727.1 - 1e-06 28.8 0.2 0.037 13.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RKP00727.1 - 3.6e-06 27.0 0.1 0.00063 19.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 RKP00727.1 - 5.2e-05 23.3 0.1 0.049 13.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 RKP00727.1 - 0.00012 21.8 0.4 0.04 13.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RKP00727.1 - 0.00013 21.9 0.3 1.1 9.1 0.2 3.1 3 0 0 3 3 3 2 NACHT domain Ploopntkinase3 PF18751.1 RKP00727.1 - 0.00083 19.3 0.1 0.44 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 RKP00727.1 - 0.0011 19.1 0.2 0.98 9.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKP00727.1 - 0.0023 18.2 0.1 0.61 10.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 RKP00727.1 - 0.0037 17.8 0.1 0.0096 16.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain PDR_assoc PF08370.11 RKP00727.1 - 0.019 14.7 1.1 0.019 14.7 1.1 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Zeta_toxin PF06414.12 RKP00727.1 - 0.021 14.1 0.2 2.2 7.5 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 RKP00727.1 - 0.023 13.5 0.1 4.1 6.1 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA PF00004.29 RKP00727.1 - 0.03 14.8 0.1 1.5 9.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 RKP00727.1 - 0.088 13.1 0.0 6.1 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RKP00727.1 - 0.18 11.2 0.0 8.3 5.8 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 RKP00727.1 - 0.2 11.2 0.9 4.6 6.8 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 RKP00727.1 - 0.24 11.1 0.0 5.8 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 RKP00727.1 - 0.31 10.9 1.8 26 4.7 0.3 3.1 3 0 0 3 3 3 0 NTPase AAA_18 PF13238.6 RKP00727.1 - 0.32 11.5 6.5 1.8 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain HalX PF08663.10 RKP00727.1 - 0.56 10.6 4.1 0.69 10.3 0.7 2.3 2 0 0 2 2 2 0 HalX domain AAA_30 PF13604.6 RKP00727.1 - 0.58 9.8 4.7 1.4 8.6 0.3 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 RKP00727.1 - 1.9 8.7 6.7 2.2 8.5 0.7 2.8 3 0 0 3 3 2 0 AAA domain ABC2_membrane_3 PF12698.7 RKP00727.1 - 2 7.4 56.0 0.25 10.4 19.6 3.5 2 2 0 2 2 2 0 ABC-2 family transporter protein CsbD PF05532.12 RKP00728.1 - 1.7e-16 59.8 9.5 1.4e-14 53.8 4.3 2.1 2 0 0 2 2 2 2 CsbD-like DUF883 PF05957.13 RKP00728.1 - 0.063 13.9 3.2 0.084 13.5 3.1 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Histidinol_dh PF00815.20 RKP00729.1 - 5.1e-153 509.9 9.3 6.4e-153 509.6 9.3 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 RKP00729.1 - 1.4e-22 79.3 0.2 2.6e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 RKP00729.1 - 4.1e-11 43.1 0.1 1.1e-10 41.8 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_14 PF13428.6 RKP00730.1 - 0.00018 22.1 0.2 0.016 16.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP00730.1 - 0.0012 19.0 0.4 0.0055 16.9 0.1 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RKP00730.1 - 0.0045 17.5 0.2 0.37 11.5 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKP00730.1 - 0.009 16.1 3.5 0.42 10.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP00730.1 - 0.069 13.3 0.1 0.53 10.5 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Homez PF11569.8 RKP00730.1 - 0.077 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez TPR_8 PF13181.6 RKP00730.1 - 0.13 12.5 0.3 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat BCAS2 PF05700.11 RKP00731.1 - 2.8e-40 138.2 0.5 4e-40 137.7 0.5 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) INCENP_ARK-bind PF03941.15 RKP00731.1 - 0.022 14.7 0.8 0.041 13.8 0.8 1.4 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Ribosomal_L33 PF00471.20 RKP00732.1 - 8.4e-07 29.3 0.1 8.4e-07 29.3 0.1 1.6 2 1 0 2 2 2 1 Ribosomal protein L33 Abhydrolase_1 PF00561.20 RKP00733.1 - 1.4e-45 156.0 0.0 3.3e-45 154.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKP00734.1 - 9.9e-08 31.5 0.0 5.7e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 RKP00734.1 - 0.00059 19.5 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 RKP00734.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RKP00734.1 - 0.014 14.8 0.0 0.055 12.9 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DnaJ PF00226.31 RKP00735.1 - 9.4e-23 80.1 0.4 1.1e-22 79.9 0.4 1.0 1 0 0 1 1 1 1 DnaJ domain DUF2778 PF10908.8 RKP00735.1 - 0.072 13.4 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) CH PF00307.31 RKP00736.1 - 1e-16 61.1 0.1 3.2e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Mss4 PF04421.13 RKP00737.1 - 1.6e-11 44.2 0.0 2.6e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Mss4 protein Lar_restr_allev PF14354.6 RKP00737.1 - 0.092 13.1 0.9 0.66 10.4 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar ArfGap PF01412.18 RKP00738.1 - 1.3e-31 109.1 0.1 1.5e-31 108.9 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ribosomal_L37ae PF01780.19 RKP00738.1 - 0.061 13.4 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-RanBP PF00641.18 RKP00738.1 - 0.1 11.9 0.1 0.1 11.9 0.1 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others HATPase_c_3 PF13589.6 RKP00739.1 - 1.5e-11 44.3 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 RKP00739.1 - 5.3e-09 36.0 0.0 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 RKP00739.1 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 RKP00739.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFAP1 PF06991.11 RKP00740.1 - 3e-44 151.5 12.9 3e-44 151.5 12.9 1.5 1 1 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing AF-4 PF05110.13 RKP00740.1 - 0.28 9.2 19.1 0.04 12.0 15.4 1.4 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Borrelia_P83 PF05262.11 RKP00740.1 - 1.9 6.9 9.5 2.3 6.6 9.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Sel1 PF08238.12 RKP00741.1 - 4.1e-97 316.4 53.0 4.7e-09 36.6 0.2 14.5 14 1 0 14 14 14 13 Sel1 repeat DUF1580 PF07618.11 RKP00741.1 - 0.074 12.7 0.4 6.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) TPR_16 PF13432.6 RKP00741.1 - 0.32 11.7 29.9 6.7 7.5 0.0 7.8 7 1 1 8 8 8 0 Tetratricopeptide repeat MFS_2 PF13347.6 RKP00742.1 - 2e-06 26.7 12.3 4.1e-06 25.6 11.1 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 RKP00742.1 - 4.1e-06 26.0 16.8 1.1e-05 24.6 16.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Choline_kinase PF01633.20 RKP00743.1 - 1e-55 188.6 0.0 1.3e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 RKP00743.1 - 1.3e-08 35.0 2.2 2.3e-08 34.3 2.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RKP00743.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ribosomal_L16 PF00252.18 RKP00744.1 - 4.3e-35 120.6 0.1 4.6e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NDUF_B4 PF07225.12 RKP00745.1 - 3.2e-06 27.0 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) RRM_1 PF00076.22 RKP00746.1 - 1.1e-18 66.8 0.0 1.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKP00746.1 - 0.0038 17.1 0.0 0.0081 16.0 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 RKP00746.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.18 RKP00747.1 - 1.1e-70 237.0 0.0 1.5e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RKP00747.1 - 8.6e-20 70.1 1.5 8.6e-20 70.1 1.5 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 RKP00747.1 - 0.0031 17.9 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKP00747.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family STIMATE PF12400.8 RKP00748.1 - 3.8e-36 124.4 3.0 3.8e-36 124.4 3.0 1.5 2 0 0 2 2 2 1 STIMATE family Stk19 PF10494.9 RKP00749.1 - 1.5e-09 37.9 0.0 3.2e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 AIRC PF00731.20 RKP00750.1 - 1.5e-58 196.6 2.9 1.5e-58 196.6 2.9 2.7 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.22 RKP00750.1 - 2.5e-53 180.1 0.0 4e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 RKP00750.1 - 3e-16 58.8 0.0 6.4e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 RKP00750.1 - 2.5e-11 43.5 0.1 4.6e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 RKP00750.1 - 0.00057 19.5 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 RKP00750.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Propionate catabolism activator CoA_binding_2 PF13380.6 RKP00750.1 - 0.084 13.4 1.1 8.5 6.9 0.0 3.7 2 2 1 4 4 4 0 CoA binding domain PTS_2-RNA PF01885.16 RKP00752.1 - 1.2e-60 204.6 0.0 1.4e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PIN_10 PF18478.1 RKP00752.1 - 0.069 13.4 0.4 0.26 11.5 0.1 2.0 1 1 1 2 2 2 0 PIN like domain WD40 PF00400.32 RKP00753.1 - 4.7e-22 77.9 4.4 0.00024 21.8 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 RKP00753.1 - 0.0051 16.2 0.0 0.0096 15.3 0.0 1.5 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 RKP00753.1 - 0.023 15.0 0.0 0.91 9.9 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP00753.1 - 0.071 11.7 0.3 0.23 10.1 0.1 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 RKP00753.1 - 0.22 10.1 0.0 0.41 9.2 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Pkinase PF00069.25 RKP00755.1 - 1.9e-61 207.7 0.0 2.6e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00755.1 - 1.7e-35 122.6 0.0 2.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 RKP00755.1 - 1.7e-17 63.1 18.4 1.2e-10 41.0 9.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 RKP00755.1 - 1.9e-12 47.6 0.1 4.1e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 RKP00755.1 - 0.0016 18.7 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 RKP00755.1 - 0.0052 15.8 0.1 0.0079 15.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain COG2 PF06148.11 RKP00756.1 - 9.4e-21 74.3 0.1 2.4e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 RKP00756.1 - 1.6e-06 28.5 0.0 1.6e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 RKP00756.1 - 0.038 14.1 0.0 0.17 12.0 0.0 2.1 2 1 0 2 2 2 0 Vps51/Vps67 Baculo_PEP_C PF04513.12 RKP00756.1 - 0.31 11.1 1.0 1.3 9.1 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UCR_14kD PF02271.16 RKP00757.1 - 3.4e-27 94.3 0.0 4.6e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF2508 PF10704.9 RKP00757.1 - 0.061 13.5 0.1 0.13 12.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) ASH PF15780.5 RKP00758.1 - 1.1e-27 96.1 11.2 0.018 15.2 0.0 17.5 22 0 0 22 22 22 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RKP00758.1 - 5.9e-09 36.0 4.7 0.41 10.8 0.0 8.6 10 0 0 10 10 10 3 Flagellar-associated PapD-like DUF1573 PF07610.11 RKP00758.1 - 2.8e-06 27.3 0.0 24 5.1 0.0 9.4 11 0 0 11 11 11 1 Protein of unknown function (DUF1573) DUF11 PF01345.18 RKP00758.1 - 0.54 10.6 6.0 2 8.8 1.3 4.7 3 0 0 3 3 3 0 Domain of unknown function DUF11 Mss4 PF04421.13 RKP00759.1 - 5.1e-06 26.5 0.0 1e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Mss4 protein AAA_12 PF13087.6 RKP00761.1 - 1.3e-60 204.5 0.0 1.7e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKP00761.1 - 1.9e-30 106.6 0.2 3.4e-30 105.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 RKP00761.1 - 2.5e-05 24.2 0.2 0.065 13.0 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 RKP00761.1 - 0.007 16.2 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 RKP00761.1 - 0.061 13.7 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RKP00761.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain BCIP PF13862.6 RKP00762.1 - 1.4e-41 142.5 0.0 1.7e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein OPT PF03169.15 RKP00763.1 - 4.5e-121 405.4 49.4 5.1e-121 405.3 49.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pyr_redox_2 PF07992.14 RKP00764.1 - 1.3e-27 96.8 0.0 2.2e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKP00764.1 - 9.8e-12 45.3 1.1 6.9e-07 29.7 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 RKP00764.1 - 5e-10 39.5 3.2 0.00032 20.4 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 RKP00764.1 - 1.1e-05 24.9 0.0 0.008 15.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.19 RKP00764.1 - 3.8e-05 23.9 0.0 7.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain UDPG_MGDP_dh_N PF03721.14 RKP00764.1 - 8e-05 22.3 0.8 0.0048 16.5 0.2 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 RKP00764.1 - 9.7e-05 22.8 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 RKP00764.1 - 0.0002 21.5 7.1 0.0014 18.8 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RKP00764.1 - 0.0003 20.1 1.2 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 RKP00764.1 - 0.0004 19.6 1.0 0.024 13.7 0.0 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 RKP00764.1 - 0.00042 19.3 0.8 0.04 12.8 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 RKP00764.1 - 0.00043 19.5 0.1 0.00043 19.5 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 RKP00764.1 - 0.0014 17.4 0.1 0.053 12.2 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 RKP00764.1 - 0.0032 16.8 1.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 RKP00764.1 - 0.012 15.6 7.2 0.11 12.5 0.0 3.9 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 RKP00764.1 - 0.019 14.0 0.1 0.019 14.0 0.1 2.9 3 0 0 3 3 2 0 Lycopene cyclase protein ApbA PF02558.16 RKP00764.1 - 0.028 14.1 0.5 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PilM_2 PF11104.8 RKP00764.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Sacchrp_dh_NADP PF03435.18 RKP00764.1 - 0.081 13.2 0.2 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 RKP00764.1 - 5.1 6.4 5.6 24 4.2 0.1 2.8 3 0 0 3 3 3 0 ThiF family WD40 PF00400.32 RKP00765.1 - 4.6e-70 229.8 22.7 5.3e-09 36.6 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00765.1 - 1.7e-21 76.3 0.7 0.002 18.4 0.0 5.5 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP00765.1 - 8.8e-08 31.5 0.1 0.015 14.3 0.0 3.9 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKP00765.1 - 3.3e-05 23.9 0.0 0.65 9.9 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RKP00765.1 - 6.1e-05 21.9 7.9 1.5 7.4 0.0 4.7 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Frtz PF11768.8 RKP00765.1 - 7.8e-05 21.2 0.0 0.19 10.0 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 RKP00765.1 - 0.0046 16.3 0.4 1.7 7.9 0.0 3.2 3 2 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 RKP00765.1 - 0.019 13.5 0.0 0.82 8.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain FAD_binding_9 PF08021.11 RKP00765.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 RKP00765.1 - 0.043 13.1 0.0 7.6 5.8 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 RKP00765.1 - 0.058 13.3 6.2 3.8 7.6 0.1 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 RKP00765.1 - 0.54 10.0 2.1 17 5.2 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Golgin_A5 PF09787.9 RKP00767.1 - 0.84 9.0 108.9 0.098 12.1 31.8 4.8 1 1 3 4 4 4 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 RKP00767.1 - 1.1 9.7 12.2 47 4.5 0.3 6.1 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) SH3_9 PF14604.6 RKP00768.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP00768.1 - 1.1e-06 28.1 0.0 2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF202 PF02656.15 RKP00768.1 - 0.059 13.8 0.2 0.14 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF3147 PF11345.8 RKP00768.1 - 0.11 12.8 0.2 0.2 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) SH3_2 PF07653.17 RKP00768.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Fibrillin_U_N PF18193.1 RKP00768.1 - 0.98 9.6 2.9 4.5 7.5 0.2 2.7 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain Glycos_transf_2 PF00535.26 RKP00769.1 - 2e-26 92.8 0.0 2.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RKP00769.1 - 7e-10 39.2 0.0 9.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RKP00769.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 BAR PF03114.18 RKP00770.1 - 2.1e-46 158.5 1.3 2.5e-46 158.2 1.3 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RKP00770.1 - 0.057 13.1 0.3 0.11 12.2 0.3 1.6 1 1 0 1 1 1 0 BAR domain of APPL family Sec34 PF04136.15 RKP00770.1 - 0.098 12.5 0.3 0.25 11.2 0.3 1.8 1 1 0 1 1 1 0 Sec34-like family Arfaptin PF06456.13 RKP00770.1 - 0.21 11.1 2.4 0.39 10.3 0.2 1.9 2 0 0 2 2 2 0 Arfaptin-like domain P5CR_dimer PF14748.6 RKP00772.1 - 8.3e-34 115.9 2.1 8.3e-34 115.9 2.1 2.0 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 RKP00772.1 - 9.9e-18 64.5 2.6 9.9e-18 64.5 2.6 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 RKP00772.1 - 0.00027 21.1 0.6 0.00053 20.2 0.6 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 RKP00772.1 - 0.0046 17.0 0.2 0.018 15.1 0.3 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 RKP00772.1 - 0.022 14.3 0.7 0.035 13.7 0.7 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 RKP00772.1 - 0.039 13.9 7.2 0.27 11.2 6.6 2.3 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 RKP00772.1 - 0.082 12.6 3.4 0.13 11.9 2.0 2.1 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA CBP_BcsO PF17037.5 RKP00772.1 - 2.2 8.4 5.1 3.9 7.6 5.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO SAE2 PF08573.10 RKP00773.1 - 8.9e-13 49.3 6.5 1.5e-05 26.1 0.2 3.2 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF4407 PF14362.6 RKP00773.1 - 0.017 14.5 0.2 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 RKP00773.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator CS PF04969.16 RKP00774.1 - 2.9e-07 31.4 0.0 4.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 RKP00774.1 - 0.00039 20.1 0.3 0.2 11.6 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKP00774.1 - 0.13 12.4 9.5 0.17 12.1 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ORMDL PF04061.14 RKP00775.1 - 8.3e-50 168.1 4.3 9.1e-50 168.0 4.3 1.0 1 0 0 1 1 1 1 ORMDL family zf-C2H2_aberr PF17017.5 RKP00777.1 - 4.4e-06 27.0 0.1 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 RKP00777.1 - 0.0048 17.6 6.7 0.99 10.4 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RKP00777.1 - 0.016 15.7 7.4 0.91 10.1 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Presenilin PF01080.17 RKP00777.1 - 2.2 7.0 13.7 3.3 6.4 13.7 1.2 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 RKP00777.1 - 2.2 8.2 6.7 3.6 7.5 6.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.13 RKP00777.1 - 4.7 7.1 49.5 2 8.3 46.7 1.7 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit BBL5 PF07289.11 RKP00777.1 - 5.9 5.8 7.3 8.7 5.3 7.3 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Miga PF10265.9 RKP00777.1 - 8 5.3 10.4 12 4.7 10.4 1.2 1 0 0 1 1 1 0 Mitoguardin zf-C2H2 PF00096.26 RKP00778.1 - 3.3e-09 36.7 10.5 6.7e-06 26.3 2.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKP00778.1 - 1.6e-07 31.4 10.4 4.8e-06 26.7 3.0 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKP00778.1 - 1e-06 29.0 9.1 0.00043 20.9 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKP00778.1 - 0.0092 15.7 2.2 0.0092 15.7 2.2 1.8 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-DNA_Pol PF08996.10 RKP00778.1 - 0.029 14.1 1.0 0.033 13.9 1.0 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2_jaz PF12171.8 RKP00778.1 - 0.048 14.0 0.4 0.048 14.0 0.4 2.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP00778.1 - 0.07 13.1 9.3 1.3 9.1 4.1 3.2 2 2 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 RKP00778.1 - 0.18 12.2 8.8 0.71 10.3 1.4 2.6 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC PF01530.18 RKP00778.1 - 4.4 7.6 10.7 1.2 9.4 2.9 2.6 2 1 0 2 2 2 0 Zinc finger, C2HC type tRNA_int_end_N2 PF12928.7 RKP00779.1 - 4.1e-12 46.1 0.0 7e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 RKP00779.1 - 0.0005 19.7 0.0 0.00089 18.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain LIM PF00412.22 RKP00782.1 - 3.5e-51 171.3 51.6 6.2e-13 48.8 2.3 5.4 6 0 0 6 6 6 5 LIM domain DUF2685 PF10886.8 RKP00782.1 - 0.042 14.0 13.9 24 5.2 0.0 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF2685) Sgf11 PF08209.11 RKP00782.1 - 0.12 12.0 0.2 0.12 12.0 0.2 6.4 8 0 0 8 8 8 0 Sgf11 (transcriptional regulation protein) F-actin_cap_A PF01267.17 RKP00783.1 - 1.4e-66 224.7 0.0 1.6e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit MutL_C PF08676.11 RKP00784.1 - 2.4e-26 92.3 0.0 4.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 RKP00784.1 - 6.9e-17 61.2 0.0 1.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RKP00784.1 - 5e-08 32.9 0.0 8.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RKP00784.1 - 0.0004 20.9 0.0 0.00072 20.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ACBP PF00887.19 RKP00785.1 - 4.2e-26 91.0 0.0 4.6e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein UQ_con PF00179.26 RKP00786.1 - 9.8e-39 132.2 0.1 1.2e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKP00786.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain HAD_SAK_1 PF10307.9 RKP00788.1 - 1.8e-26 93.2 0.0 2.8e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Mur_ligase_M PF08245.12 RKP00789.1 - 5.5e-08 33.0 0.0 7.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Kinesin PF00225.23 RKP00790.1 - 1.1e-76 257.9 0.0 1.2e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP00790.1 - 3.6e-10 40.0 0.0 5.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding DUF3235 PF11574.8 RKP00790.1 - 0.12 13.2 0.0 0.39 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DIL PF01843.19 RKP00791.1 - 1.1e-23 83.5 0.2 3.1e-23 82.0 0.2 1.8 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 RKP00791.1 - 2e-12 47.5 0.2 5.1e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKP00791.1 - 4.6e-08 33.5 0.8 5.8e-07 29.9 0.1 3.0 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 RKP00791.1 - 2.5e-06 27.7 1.5 0.00015 22.0 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP00791.1 - 9.6e-06 25.6 1.8 0.054 14.1 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 RKP00791.1 - 1.1e-05 25.7 0.1 0.00078 19.8 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat SNARE_assoc PF09335.11 RKP00791.1 - 0.17 12.3 0.2 0.47 11.0 0.2 1.7 1 0 0 1 1 1 0 SNARE associated Golgi protein TFIIB PF00382.19 RKP00792.1 - 2.9e-33 113.7 0.4 6.6e-21 74.1 0.5 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 RKP00792.1 - 9.4e-14 50.7 0.8 1.7e-13 49.8 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 RKP00792.1 - 0.0094 16.0 1.1 0.026 14.6 1.0 1.7 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 RKP00792.1 - 0.087 12.3 0.8 1.2 8.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TA0956 PF11513.8 RKP00792.1 - 0.097 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 HARE-HTH PF05066.13 RKP00792.1 - 0.11 12.9 0.2 0.43 11.0 0.2 2.0 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Cyclin_N PF00134.23 RKP00792.1 - 0.13 12.0 0.3 0.3 10.8 0.2 1.6 1 1 1 2 2 2 0 Cyclin, N-terminal domain MiAMP1 PF09117.10 RKP00792.1 - 0.17 12.1 1.9 0.76 10.1 0.0 2.6 3 0 0 3 3 3 0 MiAMP1 TFA2_Winged_2 PF18121.1 RKP00794.1 - 1.7e-16 59.6 0.1 3.9e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 RKP00794.1 - 1.4e-06 28.4 1.0 5.2e-06 26.7 0.7 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain FUSC_2 PF13515.6 RKP00795.1 - 9.5e-19 67.8 9.5 1.4e-18 67.3 9.5 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 RKP00795.1 - 4.2e-11 42.1 13.7 6.6e-11 41.5 13.7 1.5 1 1 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 RKP00795.1 - 0.00082 18.3 3.7 0.002 17.1 3.7 1.5 1 1 0 1 1 1 1 Aluminium activated malate transporter Pox_E8 PF03394.13 RKP00796.1 - 0.0037 16.9 0.1 0.004 16.7 0.1 1.0 1 0 0 1 1 1 1 Poxvirus E8 protein SNARE PF05739.19 RKP00796.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 SNARE domain Use1 PF09753.9 RKP00796.1 - 0.037 13.8 0.4 0.042 13.6 0.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Tropomyosin PF00261.20 RKP00796.1 - 0.06 12.7 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Tropomyosin Sec20 PF03908.13 RKP00796.1 - 0.091 12.7 0.4 0.13 12.1 0.3 1.3 1 1 0 1 1 1 0 Sec20 DUF1664 PF07889.12 RKP00796.1 - 0.096 12.7 0.3 0.12 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_trans_2_3 PF13632.6 RKP00797.1 - 1.5e-16 60.9 4.8 2.9e-16 60.0 4.8 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 CRAL_TRIO PF00650.20 RKP00798.1 - 4.1e-14 52.6 0.0 1.3e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain SNARE_assoc PF09335.11 RKP00798.1 - 2e-12 47.6 8.1 8.9e-12 45.6 8.1 2.2 1 0 0 1 1 1 1 SNARE associated Golgi protein CRAL_TRIO_2 PF13716.6 RKP00798.1 - 0.0042 17.2 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DnaJ_CXXCXGXG PF00684.19 RKP00799.1 - 7.7e-06 26.2 45.5 0.0063 16.9 8.9 5.0 2 2 1 4 4 4 4 DnaJ central domain Ank_2 PF12796.7 RKP00800.1 - 8.6e-18 64.7 0.6 5.1e-06 27.0 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKP00800.1 - 1.9e-15 55.4 7.3 0.0021 18.4 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 RKP00800.1 - 2.1e-12 47.3 2.2 0.019 15.5 0.1 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RKP00800.1 - 7e-12 45.3 2.0 0.018 15.4 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RKP00800.1 - 2.1e-09 37.4 15.7 0.0021 18.4 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat UQ_con PF00179.26 RKP00801.1 - 1.5e-36 125.1 0.0 1.7e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MIP-T3 PF10243.9 RKP00802.1 - 1.3e-32 112.1 0.0 2.1e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 RKP00802.1 - 1.7e-16 60.6 0.4 4.9e-16 59.1 0.4 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region Drc1-Sld2 PF11719.8 RKP00803.1 - 5.2e-12 46.1 9.5 1.1e-10 41.7 0.0 3.7 4 0 0 4 4 4 2 DNA replication and checkpoint protein Helicase_C PF00271.31 RKP00803.1 - 0.01 16.2 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain NLRC4_HD PF17889.1 RKP00804.1 - 0.0036 17.6 0.0 0.004 17.5 0.0 1.1 1 0 0 1 1 1 1 NLRC4 helical domain PX PF00787.24 RKP00805.1 - 6.5e-17 61.5 0.6 1.7e-16 60.2 0.6 1.6 1 0 0 1 1 1 1 PX domain Plasmid_RAQPRD PF09686.10 RKP00805.1 - 5.7 7.2 6.1 1.2 9.4 1.1 2.5 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LRR_6 PF13516.6 RKP00806.1 - 7.3e-13 47.5 0.4 1.5 9.1 0.0 8.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 RKP00806.1 - 3.9e-06 27.1 0.6 11 6.6 0.1 5.6 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP00806.1 - 2.8e-05 23.8 1.5 1 9.1 0.2 4.8 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 RKP00806.1 - 0.00013 22.0 0.0 65 4.7 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat IPK PF03770.16 RKP00807.1 - 1.4e-26 93.6 0.0 3.2e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase ABC_tran PF00005.27 RKP00808.1 - 1.5e-47 161.5 0.0 1.6e-26 93.5 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 RKP00808.1 - 1.1e-15 58.3 2.6 0.00093 19.1 0.0 4.2 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RKP00808.1 - 6.6e-13 48.6 2.7 3.7e-06 26.5 0.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RKP00808.1 - 9.7e-09 36.0 0.3 0.0028 18.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 RKP00808.1 - 2.7e-07 30.7 0.0 0.0068 16.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 RKP00808.1 - 2.1e-06 27.4 0.4 0.073 12.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 RKP00808.1 - 2.6e-06 28.0 0.0 0.027 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RKP00808.1 - 6.8e-06 26.4 0.0 0.0092 16.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKP00808.1 - 8.1e-05 22.9 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RKP00808.1 - 8.1e-05 22.8 0.0 0.22 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 RKP00808.1 - 8.2e-05 22.5 0.1 0.12 12.0 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 RKP00808.1 - 9e-05 22.4 0.2 0.14 12.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 RKP00808.1 - 0.00021 21.4 1.2 0.099 12.7 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_16 PF13191.6 RKP00808.1 - 0.0003 21.2 0.0 1.3 9.4 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 RKP00808.1 - 0.00037 19.6 0.4 0.27 10.2 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 RKP00808.1 - 0.00038 20.4 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_27 PF13514.6 RKP00808.1 - 0.00045 19.9 0.2 0.69 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 RKP00808.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_30 PF13604.6 RKP00808.1 - 0.00085 19.1 0.1 0.58 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RKP00808.1 - 0.0018 18.6 0.0 0.95 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 RKP00808.1 - 0.0027 17.9 0.0 2.6 8.3 0.0 2.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 RKP00808.1 - 0.0052 17.0 0.1 8.6 6.7 0.0 3.5 4 2 0 4 4 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 RKP00808.1 - 0.0063 16.9 0.0 5.6 7.4 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 RKP00808.1 - 0.0078 16.3 0.5 6.4 6.8 0.1 2.9 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 RKP00808.1 - 0.01 15.1 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 RKP00808.1 - 0.02 14.5 1.0 7.4 6.1 0.0 3.1 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 RKP00808.1 - 0.026 14.4 0.1 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3584 PF12128.8 RKP00808.1 - 0.035 11.6 1.8 1 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_ATPase PF09818.9 RKP00808.1 - 0.035 12.9 0.1 1.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.6 RKP00808.1 - 0.04 13.9 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 RKP00808.1 - 0.041 13.8 0.2 3.8 7.4 0.0 2.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_13 PF13166.6 RKP00808.1 - 0.046 12.4 0.0 2.5 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RKP00808.1 - 0.07 12.4 0.1 9.3 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 RKP00808.1 - 0.082 12.6 0.8 2.9 7.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain MukB PF04310.12 RKP00808.1 - 0.12 12.2 0.3 16 5.2 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal ATPase_2 PF01637.18 RKP00808.1 - 0.13 12.1 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PRK PF00485.18 RKP00808.1 - 0.14 11.9 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TIP120 PF08623.10 RKP00808.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF815 PF05673.13 RKP00808.1 - 0.15 11.2 0.1 11 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 RKP00808.1 - 0.16 11.5 0.2 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 RKP00808.1 - 0.17 11.1 0.0 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 RKP00808.1 - 0.18 11.6 0.3 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT PF02985.22 RKP00808.1 - 0.39 11.1 5.3 58 4.4 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat SLX9 PF15341.6 RKP00810.1 - 0.0073 16.7 1.8 0.064 13.6 1.2 2.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF2722 PF10846.8 RKP00810.1 - 0.017 14.1 8.1 0.024 13.6 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 RKP00810.1 - 0.21 11.2 16.7 0.3 10.7 16.7 1.2 1 0 0 1 1 1 0 Spt20 family YabA PF06156.13 RKP00810.1 - 2 9.1 6.4 1.6e+02 3.0 6.8 2.7 2 0 0 2 2 2 0 Initiation control protein YabA Med11 PF10280.9 RKP00810.1 - 4.7 7.7 11.0 11 6.5 6.8 2.5 3 0 0 3 3 3 0 Mediator complex protein DUF2368 PF10166.9 RKP00810.1 - 6.7 6.3 12.0 13 5.4 12.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) COesterase PF00135.28 RKP00811.1 - 0.0017 17.4 0.1 0.0024 16.8 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 RKP00811.1 - 0.016 14.7 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 RKP00811.1 - 0.075 12.3 0.2 0.65 9.2 0.0 2.1 2 1 0 2 2 2 0 Serine aminopeptidase, S33 MASE2 PF05230.11 RKP00811.1 - 0.086 12.9 0.3 1.6 8.9 0.2 2.3 2 0 0 2 2 2 0 MASE2 domain Rcd1 PF04078.13 RKP00812.1 - 8.8e-125 415.2 1.1 1e-124 415.0 1.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like KilA-N PF04383.13 RKP00813.1 - 2.2e-05 24.3 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain Mitochondr_Som1 PF11093.8 RKP00814.1 - 1.9e-05 24.6 0.1 3.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 ATG7_N PF16420.5 RKP00815.1 - 7e-65 219.6 0.0 9e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 RKP00815.1 - 4.1e-43 147.5 0.0 6.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 RKP00815.1 - 0.062 13.4 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 RKP00815.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Slu7 PF11708.8 RKP00816.1 - 1.2e-95 320.3 5.1 1.9e-95 319.7 5.1 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 RKP00816.1 - 0.019 14.7 0.5 0.039 13.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Sigma70_r2 PF04542.14 RKP00816.1 - 0.051 13.3 0.9 0.1 12.4 0.9 1.5 1 0 0 1 1 1 0 Sigma-70 region 2 PhoLip_ATPase_C PF16212.5 RKP00818.1 - 1.6e-65 221.4 25.0 1.6e-65 221.4 25.0 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKP00818.1 - 5.3e-19 67.7 0.9 5.3e-19 67.7 0.9 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RKP00818.1 - 2.9e-11 44.1 0.7 7.2e-05 23.2 0.2 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP00818.1 - 6.2e-11 42.2 0.0 4.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKP00818.1 - 4.1e-05 23.4 0.5 0.00026 20.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RKP00818.1 - 0.0001 21.9 0.0 0.00073 19.1 0.0 2.4 2 2 1 3 3 3 1 E1-E2 ATPase DUF2946 PF11162.8 RKP00818.1 - 0.1 13.2 0.9 3.8 8.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) HSF_DNA-bind PF00447.17 RKP00819.1 - 1.1e-18 67.6 0.0 1.1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Velvet PF11754.8 RKP00819.1 - 0.0076 16.2 1.6 0.0076 16.2 1.6 3.0 3 0 0 3 3 3 1 Velvet factor DDHD PF02862.17 RKP00819.1 - 0.021 15.0 0.9 0.021 15.0 0.9 2.2 2 0 0 2 2 2 0 DDHD domain SpoIIP PF07454.11 RKP00819.1 - 0.33 10.4 7.0 0.59 9.5 7.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 RKP00819.1 - 0.51 10.7 9.2 1.4 9.3 9.2 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like Lin-8 PF03353.15 RKP00819.1 - 1.3 8.5 12.5 2.9 7.4 12.5 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 RKP00819.1 - 2.4 7.1 8.7 4.2 6.3 8.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 RKP00819.1 - 3.5 6.5 14.0 6.3 5.7 14.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3523 PF12037.8 RKP00819.1 - 6.6 6.0 20.7 11 5.3 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) ALMT PF11744.8 RKP00819.1 - 7.1 5.3 7.8 12 4.6 7.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Cyclin_N PF00134.23 RKP00820.1 - 1.2e-48 164.0 0.0 2.2e-46 156.7 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RKP00820.1 - 1.4e-34 118.8 0.0 2.4e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF543 PF04418.12 RKP00822.1 - 1.6e-24 85.7 0.1 1.8e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF3100 PF11299.8 RKP00822.1 - 0.099 12.0 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) Got1 PF04178.12 RKP00823.1 - 4.1e-31 107.7 16.0 6.1e-31 107.2 16.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family GTP_cyclohydroI PF01227.22 RKP00823.1 - 0.057 12.8 0.1 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 GTP cyclohydrolase I DUF3561 PF12084.8 RKP00823.1 - 0.85 9.7 12.9 3.6 7.7 12.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) Cation_efflux PF01545.21 RKP00824.1 - 1.2e-42 145.9 5.1 1.6e-42 145.5 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1744 PF08490.12 RKP00825.1 - 1.5e-92 310.3 0.0 2.3e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 RKP00825.1 - 4.8e-70 236.3 0.2 8.8e-70 235.5 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 RKP00825.1 - 2.2e-13 49.7 0.0 1.7e-10 40.3 0.0 3.8 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 RKP00825.1 - 1.1e-07 31.7 0.1 3.3e-07 30.2 0.1 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 RKP00825.1 - 0.00016 21.7 0.0 0.00046 20.2 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily Methyltransf_11 PF08241.12 RKP00826.1 - 4e-13 49.8 0.0 8.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP00826.1 - 4.5e-11 43.3 0.3 2.5e-10 40.9 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP00826.1 - 1.1e-05 26.1 0.0 3.6e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP00826.1 - 0.0049 16.7 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKP00826.1 - 0.067 13.0 0.1 0.32 10.8 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain zf-CCHC PF00098.23 RKP00827.1 - 3.4e-06 26.9 3.0 3.4e-06 26.9 3.0 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 RKP00827.1 - 4.2e-05 23.3 3.4 4.2e-05 23.3 3.4 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 RKP00827.1 - 0.076 13.0 1.3 0.076 13.0 1.3 1.8 2 0 0 2 2 2 0 Zinc knuckle Spuma_A9PTase PF03539.14 RKP00828.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) LRR_4 PF12799.7 RKP00829.1 - 0.0075 16.7 0.1 7.1 7.2 0.0 3.8 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RKP00829.1 - 0.0082 16.1 0.0 2.5 8.4 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat DAGK_acc PF00609.19 RKP00830.1 - 1.3e-35 123.1 0.0 1e-16 61.7 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RKP00830.1 - 2.2e-19 69.3 0.0 4.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RKP00830.1 - 1.7e-07 31.0 19.3 9e-07 28.7 5.1 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Sds3 PF08598.11 RKP00832.1 - 0.47 10.4 6.2 0.78 9.7 6.2 1.2 1 0 0 1 1 1 0 Sds3-like Abhydrolase_1 PF00561.20 RKP00834.1 - 6.8e-05 22.6 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 RKP00834.1 - 0.0085 16.0 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 RKP00834.1 - 0.0088 15.3 1.5 0.21 10.8 1.2 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 6PF2K PF01591.18 RKP00836.1 - 2.3e-66 223.3 0.0 1.2e-40 139.3 0.2 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 RKP00836.1 - 5.6e-33 114.3 4.2 5e-27 94.9 0.0 3.1 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 RKP00836.1 - 0.0039 17.4 3.0 0.17 12.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain KTI12 PF08433.10 RKP00836.1 - 0.038 13.4 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RXT2_N PF08595.11 RKP00836.1 - 0.17 11.9 4.6 0.47 10.5 4.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF572 PF04502.13 RKP00836.1 - 0.17 11.5 1.2 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) RNA_pol_3_Rpc31 PF11705.8 RKP00836.1 - 0.23 11.7 9.0 0.49 10.6 9.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 RKP00836.1 - 0.25 11.3 17.5 0.047 13.7 10.5 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.11 RKP00836.1 - 0.41 10.0 11.5 0.075 12.4 6.4 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF3439 PF11921.8 RKP00836.1 - 2.2 8.3 18.1 0.066 13.2 8.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) MARVEL PF01284.23 RKP00837.1 - 9.3e-05 22.5 7.4 0.00015 21.8 7.4 1.4 1 0 0 1 1 1 1 Membrane-associating domain Tyrosinase PF00264.20 RKP00838.1 - 6.3e-33 114.9 7.2 1.6e-32 113.6 7.2 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Ribosomal_L11 PF00298.19 RKP00840.1 - 2.6e-26 91.9 0.4 3.8e-26 91.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 RKP00840.1 - 6.3e-26 90.0 0.2 1.2e-25 89.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain ATP_synt_H PF05493.13 RKP00841.1 - 1e-17 64.3 1.8 1.2e-17 64.1 1.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H EI24 PF07264.11 RKP00841.1 - 0.027 14.7 2.9 0.032 14.5 2.9 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) ARL6IP6 PF15062.6 RKP00841.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix CAAD PF14159.6 RKP00841.1 - 0.41 10.5 2.9 2.4 8.0 0.7 2.0 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase APH PF01636.23 RKP00842.1 - 0.0014 18.6 12.4 0.2 11.5 8.4 2.9 2 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RKP00842.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 RKP00842.1 - 0.016 14.6 2.3 0.26 10.6 2.4 2.4 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 RKP00842.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Amido_AtzD_TrzD PF09663.10 RKP00842.1 - 0.03 13.3 0.7 0.041 12.9 0.7 1.2 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Pkinase_fungal PF17667.1 RKP00842.1 - 0.15 10.8 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RNA_pol_Rpb4 PF03874.16 RKP00843.1 - 5.5e-20 71.9 0.0 7.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Gar1 PF04410.14 RKP00845.1 - 2.9e-28 98.6 0.0 3.7e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Peptidase_M17 PF00883.21 RKP00847.1 - 6.9e-63 212.8 0.2 9.5e-63 212.3 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Cpn60_TCP1 PF00118.24 RKP00848.1 - 6.5e-85 285.6 13.2 1.2e-84 284.8 13.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Alpha-amylase PF00128.24 RKP00849.1 - 3.8e-22 79.3 0.1 4.4e-15 56.1 0.0 3.1 2 1 1 3 3 3 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 RKP00849.1 - 2.3e-07 31.0 3.7 1.1e-06 28.8 3.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3459) WD40_4 PF16300.5 RKP00850.1 - 1.6e-16 59.9 0.0 6.2e-08 32.4 0.0 2.8 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 RKP00850.1 - 1.5e-15 57.3 2.3 0.085 13.8 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00850.1 - 6.9e-10 39.1 0.0 0.014 15.6 0.0 5.0 5 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 RKP00850.1 - 0.027 14.3 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) WDCP PF15390.6 RKP00850.1 - 0.17 10.2 0.0 0.35 9.2 0.0 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Nup160 PF11715.8 RKP00850.1 - 0.32 9.6 0.3 4 6.0 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nop PF01798.18 RKP00851.1 - 1.2e-69 234.3 0.0 1.2e-69 234.3 0.0 2.5 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RKP00851.1 - 1.1e-09 38.6 0.1 1.1e-09 38.6 0.1 3.2 2 2 0 2 2 2 1 NOP5NT (NUC127) domain DUF1776 PF08643.10 RKP00851.1 - 0.033 13.5 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_kinase PF01513.21 RKP00852.1 - 4.2e-49 167.3 0.0 7.5e-49 166.5 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RKP00852.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RhoGAP PF00620.27 RKP00853.1 - 4.5e-41 140.2 0.0 9.4e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 RKP00853.1 - 6.3e-13 48.8 0.0 2.4e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 RKP00853.1 - 0.02 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 BAR domain of APPL family DUF4085 PF13315.6 RKP00853.1 - 0.081 12.5 0.4 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Sas10_Utp3 PF04000.15 RKP00854.1 - 8.3e-11 42.4 0.5 2.4e-10 40.9 0.5 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Coat_F PF07875.12 RKP00854.1 - 2.9 8.2 4.8 19 5.6 0.4 2.6 2 0 0 2 2 2 0 Coat F domain GCS PF03074.16 RKP00855.1 - 4.7e-137 457.2 0.0 1e-135 452.8 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase CTD_bind PF04818.13 RKP00857.1 - 4.4e-08 33.8 0.0 1.1e-07 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 RKP00857.1 - 1.1 8.9 7.6 0.32 10.6 3.0 2.4 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Muskelin_N PF06588.11 RKP00858.1 - 2.4e-66 223.5 0.0 3.5e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_5 PF13854.6 RKP00858.1 - 3.1e-19 68.5 0.4 0.0002 21.3 0.0 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 RKP00858.1 - 8.1e-19 67.4 7.4 1.4e-06 28.5 0.3 7.3 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 RKP00858.1 - 1.5e-17 63.3 6.3 0.0022 18.0 0.2 6.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 RKP00858.1 - 3.2e-12 46.2 3.9 0.05 13.9 0.1 6.0 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 RKP00858.1 - 1.1e-10 40.9 7.4 2.8e-06 26.8 0.1 5.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 RKP00858.1 - 1.1e-08 34.7 3.0 0.041 13.9 0.1 6.4 6 0 0 6 6 6 2 Kelch motif F5_F8_type_C PF00754.25 RKP00858.1 - 6e-08 32.9 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain SF3A2 PF16835.5 RKP00859.1 - 4.4e-27 94.3 0.0 7.9e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 RKP00859.1 - 1.4e-05 25.3 4.1 3.8e-05 23.9 4.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RKP00859.1 - 0.033 14.5 4.3 0.033 14.5 4.3 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mce4_CUP1 PF11887.8 RKP00859.1 - 0.077 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative zf-U1 PF06220.12 RKP00859.1 - 0.42 10.4 2.6 0.76 9.6 1.2 2.1 2 0 0 2 2 2 0 U1 zinc finger Pkinase PF00069.25 RKP00861.1 - 1.3e-64 218.1 0.0 1.5e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00861.1 - 5.5e-35 120.9 0.0 7.4e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00861.1 - 9.6e-08 31.7 0.0 0.0004 19.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 RKP00861.1 - 4.1e-05 23.6 0.2 0.0013 18.7 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP00861.1 - 0.00014 20.9 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 RKP00861.1 - 0.0019 17.9 0.3 2.7 7.6 0.0 2.5 1 1 2 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 RKP00861.1 - 0.0088 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 RKP00861.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aminotran_5 PF00266.19 RKP00862.1 - 4.2e-41 141.1 0.0 5e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Phage_holin_7_1 PF16081.5 RKP00862.1 - 0.092 12.9 0.9 0.25 11.5 0.9 1.7 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Carn_acyltransf PF00755.20 RKP00863.1 - 9e-186 619.0 0.0 1e-185 618.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Gti1_Pac2 PF09729.9 RKP00864.1 - 4.4 7.4 39.7 1.4 9.0 0.9 4.6 4 0 0 4 4 4 0 Gti1/Pac2 family AMP-binding PF00501.28 RKP00865.1 - 8.2e-33 113.6 0.0 1.9e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 RKP00865.1 - 2.3e-06 26.6 0.9 0.007 15.1 0.0 2.6 3 0 0 3 3 3 2 Condensation domain AMP-binding_C PF13193.6 RKP00865.1 - 0.00013 22.9 0.0 0.0003 21.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TB2_DP1_HVA22 PF03134.19 RKP00866.1 - 2.1e-29 101.3 3.8 2.1e-29 101.3 3.8 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 RKP00866.1 - 0.079 13.2 3.7 2.8 8.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2516 PF10724.9 RKP00866.1 - 0.29 11.5 5.4 0.59 10.5 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) Lyase_1 PF00206.20 RKP00867.1 - 9.8e-123 409.5 0.0 1.3e-122 409.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 RKP00867.1 - 7e-25 87.2 1.4 1.9e-24 85.8 0.5 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus Acetyltransf_3 PF13302.7 RKP00868.1 - 0.0018 18.9 0.1 0.17 12.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF4611 PF15387.6 RKP00868.1 - 1.6 9.0 6.8 4.7 7.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ras PF00071.22 RKP00869.1 - 1.5e-59 200.2 0.4 2e-59 199.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP00869.1 - 6.6e-37 126.4 0.1 1e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP00869.1 - 2.2e-14 53.3 0.1 2.8e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RKP00869.1 - 6.2e-07 29.0 0.1 7.6e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RKP00869.1 - 3.1e-05 23.6 0.1 0.00021 20.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKP00869.1 - 6.8e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RKP00869.1 - 0.00015 21.2 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RKP00869.1 - 0.00037 20.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 RKP00869.1 - 0.0086 15.9 0.1 0.03 14.1 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 RKP00869.1 - 0.029 13.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TetR_C_16 PF17920.1 RKP00869.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_7 PF12775.7 RKP00869.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RKP00869.1 - 0.14 12.4 0.1 15 5.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.15 RKP00871.1 - 7.5e-71 237.8 0.0 3.1e-69 232.5 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase fn3_3 PF14686.6 RKP00871.1 - 0.056 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II Peptidase_S10 PF00450.22 RKP00872.1 - 1.4e-61 209.2 0.8 9e-61 206.5 0.8 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase AAA PF00004.29 RKP00873.1 - 5e-38 130.5 0.0 1.7e-37 128.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RKP00873.1 - 1.1e-10 41.4 0.0 3.8e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 RKP00873.1 - 1.8e-10 40.4 0.2 8.5e-10 38.3 0.2 2.3 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 RKP00873.1 - 1.6e-06 28.0 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RKP00873.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKP00873.1 - 0.00071 19.6 0.1 0.003 17.6 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP00873.1 - 0.0016 18.7 0.1 0.0046 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 RKP00873.1 - 0.0017 17.6 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 RKP00873.1 - 0.0028 18.1 0.0 0.0057 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RKP00873.1 - 0.0033 17.6 0.1 0.0057 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKP00873.1 - 0.0039 16.6 0.1 0.0076 15.7 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RKP00873.1 - 0.008 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 RKP00873.1 - 0.0081 16.7 0.3 0.046 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 RKP00873.1 - 0.01 15.6 0.1 0.024 14.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 RKP00873.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKP00873.1 - 0.021 15.2 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 RKP00873.1 - 0.038 13.5 0.1 0.09 12.3 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 RKP00873.1 - 0.04 13.2 0.1 0.83 9.0 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.6 RKP00873.1 - 0.045 14.0 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 RKP00873.1 - 0.074 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 RKP00873.1 - 0.092 13.2 0.2 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 RKP00873.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 RKP00873.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 RKP00873.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 RKP00873.1 - 0.15 11.2 0.0 0.51 9.5 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 RKP00873.1 - 0.18 11.4 0.3 0.96 9.0 0.2 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RKP00873.1 - 0.2 11.4 0.0 0.69 9.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain SHIPPO-rpt PF07004.12 RKP00874.1 - 1.3e-06 29.0 30.6 0.86 10.6 0.0 8.1 8 0 0 8 8 8 6 Sperm-tail PG-rich repeat Gag_p19 PF02228.16 RKP00874.1 - 0.035 14.6 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Major core protein p19 DUF1764 PF08576.10 RKP00875.1 - 1.6e-17 64.2 0.1 6.2e-16 59.1 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Arf PF00025.21 RKP00876.1 - 9.4e-68 227.1 0.0 1.1e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RKP00876.1 - 2.6e-12 47.0 0.0 3.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RKP00876.1 - 2.2e-09 36.9 0.1 0.00023 20.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RKP00876.1 - 8.1e-09 35.3 0.0 9.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RKP00876.1 - 2.5e-08 33.6 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKP00876.1 - 4.1e-08 32.9 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKP00876.1 - 1.8e-07 31.2 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RKP00876.1 - 0.00089 19.5 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 RKP00876.1 - 0.0013 18.4 0.0 0.065 12.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 RKP00876.1 - 0.0062 16.5 0.3 0.072 13.0 0.3 2.0 1 1 0 1 1 1 1 NACHT domain MeaB PF03308.16 RKP00876.1 - 0.011 14.7 0.0 0.07 12.1 0.0 2.1 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RKP00876.1 - 0.024 14.2 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 RKP00876.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 RKP00876.1 - 0.12 13.0 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Tim17 PF02466.19 RKP00877.1 - 0.039 14.3 0.0 0.55 10.6 0.0 2.4 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 RKP00877.1 - 0.71 9.8 3.0 21 5.1 0.1 2.9 2 1 1 3 3 3 0 Mitochondrial carrier protein CASP_C PF08172.12 RKP00878.1 - 1.2e-49 169.0 0.2 1.2e-49 169.0 0.2 3.7 3 1 0 3 3 3 2 CASP C terminal NOT2_3_5 PF04153.18 RKP00879.1 - 2.7e-26 92.2 0.0 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-MIZ PF02891.20 RKP00881.1 - 3e-12 46.1 2.4 5.3e-12 45.3 2.4 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Zmiz1_N PF18028.1 RKP00881.1 - 6.6e-06 26.4 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Zmiz1 N-terminal tetratricopeptide repeat domain zf-Nse PF11789.8 RKP00881.1 - 4.9e-05 23.1 0.5 9.8e-05 22.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 RKP00881.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Y_phosphatase2 PF03162.13 RKP00882.1 - 1.5e-55 187.2 0.0 1.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKP00882.1 - 7.9e-08 32.6 0.0 8.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKP00882.1 - 0.00093 18.8 0.0 0.0011 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 RKP00882.1 - 0.0043 16.9 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PH_12 PF16457.5 RKP00883.1 - 9.4e-07 29.4 0.0 0.00052 20.5 0.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 RKP00883.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.6 1 1 0 1 1 1 0 ELMO/CED-12 family Sporozoite_P67 PF05642.11 RKP00883.1 - 0.092 10.8 0.0 0.092 10.8 0.0 5.2 5 1 1 6 6 6 0 Sporozoite P67 surface antigen Astro_capsid_p PF12226.8 RKP00883.1 - 5.8 6.0 12.8 12 5.0 12.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SDA1 PF05285.12 RKP00883.1 - 6.1 6.2 14.3 28 4.0 11.0 2.2 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 RKP00883.1 - 7 5.9 12.9 3.4 6.9 7.4 2.4 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 RKP00883.1 - 7.3 6.2 20.7 0.041 13.6 8.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ADH_N PF08240.12 RKP00884.1 - 4.2e-26 91.0 3.3 1.2e-25 89.5 3.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKP00884.1 - 2.1e-13 50.4 0.0 5.2e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase GFO_IDH_MocA PF01408.22 RKP00884.1 - 0.0014 19.4 0.0 0.0025 18.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 RKP00884.1 - 0.0056 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 RKP00885.1 - 1.4e-25 89.2 4.6 1.5e-25 89.2 1.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKP00885.1 - 1.5e-15 57.3 1.1 1.8e-15 57.1 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 RKP00885.1 - 6.1e-05 22.5 0.4 0.00011 21.7 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RKP00885.1 - 0.051 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-H2C2_5 PF13909.6 RKP00886.1 - 0.089 12.6 2.7 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Lar_restr_allev PF14354.6 RKP00886.1 - 0.15 12.5 1.1 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-C2H2_4 PF13894.6 RKP00886.1 - 1.1 10.3 4.4 1 10.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger GST_N PF02798.20 RKP00887.1 - 4.4e-14 52.6 0.0 8.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RKP00887.1 - 8.5e-13 48.3 0.4 1.7e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RKP00887.1 - 1.6e-09 38.0 0.0 3.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RKP00887.1 - 1.6e-09 37.7 0.0 3.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RKP00887.1 - 1e-08 35.3 0.0 2.7e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RKP00887.1 - 1e-07 32.2 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_S8e PF01201.22 RKP00888.1 - 1.8e-52 177.1 1.9 2.1e-52 176.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Med8 PF10232.9 RKP00889.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Med3 PF11593.8 RKP00889.1 - 4.2 6.5 5.0 6.3 5.9 5.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.7 RKP00890.1 - 4.9e-08 32.7 4.0 7.6e-08 32.1 2.2 2.4 2 0 0 2 2 2 1 F-box-like ANAPC3 PF12895.7 RKP00890.1 - 0.0028 17.9 1.4 0.13 12.5 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 RKP00890.1 - 0.062 14.0 3.1 12 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 RKP00890.1 - 1.7 8.5 6.0 18 5.2 2.1 2.7 2 0 0 2 2 2 0 XPC-binding domain Sec61_beta PF03911.16 RKP00891.1 - 2.9e-16 59.2 0.3 5.4e-16 58.3 0.3 1.5 1 0 0 1 1 1 1 Sec61beta family Shadoo PF14999.6 RKP00891.1 - 0.025 14.7 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Bac_surface_Ag PF01103.23 RKP00892.1 - 3.1e-28 99.2 0.0 5.9e-28 98.3 0.0 1.4 1 1 0 1 1 1 1 Surface antigen RasGEF PF00617.19 RKP00893.1 - 5.9e-38 130.8 0.0 1.1e-37 129.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Misat_Tub_SegII PF10644.9 RKP00894.1 - 3.7e-28 98.2 0.0 8.8e-28 97.0 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RKP00894.1 - 8.1e-18 64.7 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 RKP00894.1 - 5.8e-06 26.6 0.0 0.0038 17.4 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Sex_peptide PF08138.11 RKP00894.1 - 0.61 10.3 4.5 1.8 8.8 4.5 1.8 1 0 0 1 1 1 0 Sex peptide (SP) family Acyltransferase PF01553.21 RKP00895.1 - 4.7e-16 58.6 0.0 5.5e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Acyltransferase MDD_C PF18376.1 RKP00897.1 - 8.3e-54 182.2 0.6 1.2e-53 181.7 0.6 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 RKP00897.1 - 5.2e-07 29.8 5.4 1.8e-06 28.1 5.4 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain VWA_2 PF13519.6 RKP00898.1 - 7.7e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.25 RKP00899.1 - 1.6e-57 194.9 0.0 2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00899.1 - 4.3e-31 108.1 0.0 5.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP00899.1 - 0.0001 21.7 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RKP00899.1 - 0.00014 20.8 0.3 0.00038 19.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RKP00899.1 - 0.00034 20.6 2.1 0.25 11.3 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RKP00899.1 - 0.0022 17.6 0.3 0.011 15.4 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 RKP00899.1 - 0.44 9.9 1.9 0.75 9.1 1.9 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rrn6 PF10214.9 RKP00900.1 - 0.34 9.3 5.4 0.49 8.8 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3439 PF11921.8 RKP00901.1 - 1.6 8.7 12.0 0.21 11.6 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 RKP00902.1 - 1.5e-05 25.1 23.7 1.5e-05 25.1 23.7 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein MGC-24 PF05283.11 RKP00902.1 - 0.35 11.3 9.9 0.71 10.3 9.9 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 RKP00902.1 - 3 8.0 17.2 6.6 6.9 17.2 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus CHCH PF06747.13 RKP00903.1 - 1.6e-06 28.1 0.8 2.3e-06 27.6 0.8 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 RKP00903.1 - 0.0003 21.0 0.9 0.00037 20.7 0.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 RKP00903.1 - 0.0031 17.5 0.8 0.12 12.4 0.1 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 RKP00903.1 - 0.026 14.5 1.3 0.034 14.2 1.3 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 RKP00903.1 - 0.24 11.8 2.3 1.9 8.9 0.1 2.4 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Oxidored_FMN PF00724.20 RKP00904.1 - 4.9e-77 259.5 0.0 5.7e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Lipase_3 PF01764.25 RKP00906.1 - 5e-07 29.7 0.0 8.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RKP00906.1 - 0.0046 17.6 5.1 0.0072 17.0 4.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RKP00906.1 - 0.054 12.7 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 RKP00906.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ATP_transf PF09830.9 RKP00907.1 - 1.9e-16 59.9 0.0 4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 RKP00907.1 - 0.076 13.8 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 HIT domain SET PF00856.28 RKP00908.1 - 2e-06 28.3 0.0 0.023 15.1 0.0 3.1 3 0 0 3 3 3 2 SET domain Mucin PF01456.17 RKP00908.1 - 1.8 8.6 27.3 4.3 7.3 27.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PAP2 PF01569.21 RKP00909.1 - 1.5e-23 83.1 5.6 1.5e-23 83.1 5.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily WD40 PF00400.32 RKP00910.1 - 1.6e-39 133.1 25.2 2.2e-06 28.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP00910.1 - 4.2e-07 30.2 1.5 0.13 12.6 0.0 4.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKP00910.1 - 1.7e-06 27.8 1.0 0.01 15.4 0.0 3.1 1 1 2 3 3 3 2 PQQ-like domain DUF5046 PF16465.5 RKP00910.1 - 5.2e-05 22.8 0.1 4.5 6.6 0.0 3.5 1 1 3 4 4 4 2 Domain of unknown function (DUF5046) Nup160 PF11715.8 RKP00910.1 - 0.00026 19.8 6.6 8.1 5.0 0.0 5.1 3 3 2 5 5 5 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 RKP00910.1 - 0.00034 19.6 3.2 15 4.3 0.0 4.2 2 2 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 RKP00910.1 - 0.0015 17.6 0.2 3.3 6.7 0.0 3.4 1 1 3 4 4 4 3 Protein of unknown function (DUF1513) Frtz PF11768.8 RKP00910.1 - 0.0088 14.4 0.1 0.037 12.4 0.0 1.9 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 RKP00910.1 - 0.012 15.0 0.0 4.9 6.4 0.0 2.5 1 1 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 RKP00910.1 - 0.51 10.9 2.6 1.1e+02 3.5 0.1 4.5 5 0 0 5 5 5 0 PQQ-like domain 2-oxoacid_dh PF00198.23 RKP00911.1 - 2.5e-81 272.5 1.9 3.1e-81 272.3 1.9 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RKP00911.1 - 5.7e-14 51.7 0.1 1.2e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF5089 PF17002.5 RKP00911.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Biotin_lipoyl_2 PF13533.6 RKP00911.1 - 0.23 11.3 1.2 0.78 9.6 0.0 2.5 2 1 1 3 3 3 0 Biotin-lipoyl like CCDC53 PF10152.9 RKP00911.1 - 3.1 8.2 7.2 5.5 7.4 7.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 RKP00911.1 - 8.5 4.9 6.1 11 4.6 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Histone PF00125.24 RKP00912.1 - 3.9e-22 79.0 0.1 4.8e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKP00912.1 - 9.7e-07 29.0 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RKP00912.1 - 0.0038 17.7 0.0 0.0063 17.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 RKP00912.1 - 0.02 15.1 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein DUF2514 PF10721.9 RKP00912.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) YscO-like PF16789.5 RKP00912.1 - 0.14 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 RKP00913.1 - 3.8e-18 64.9 1.2 7.8e-18 63.9 1.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RKP00913.1 - 1.7e-15 57.5 0.0 2.2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKP00913.1 - 3.3e-05 24.1 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone STE PF02200.16 RKP00914.1 - 1.4e-39 134.9 0.0 1.7e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 STE like transcription factor PDCD2_C PF04194.13 RKP00915.1 - 7.3e-26 91.3 0.0 7.5e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CTU2 PF10288.9 RKP00915.1 - 0.062 13.6 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Rotamase_2 PF13145.6 RKP00915.1 - 0.54 11.1 6.8 0.68 10.8 2.9 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain G-alpha PF00503.20 RKP00916.1 - 5.7e-120 400.7 1.4 6.7e-120 400.5 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RKP00916.1 - 7.3e-15 54.8 1.7 4.1e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKP00916.1 - 0.00018 20.9 3.1 0.0079 15.6 0.1 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 RKP00916.1 - 0.0003 20.5 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Roc PF08477.13 RKP00916.1 - 0.0031 17.7 0.2 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RKP00916.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RKP00916.1 - 0.078 13.1 0.0 2.7 8.1 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 RKP00916.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Opi1 PF08618.10 RKP00916.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 PH PF00169.29 RKP00917.1 - 1.5e-05 25.5 0.0 2.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PH domain PRP1_N PF06424.12 RKP00917.1 - 0.075 13.4 0.4 0.13 12.7 0.4 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal ABC_tran_Xtn PF12848.7 RKP00917.1 - 0.082 12.9 2.4 0.16 12.0 2.4 1.5 1 0 0 1 1 1 0 ABC transporter Ribosomal_S11 PF00411.19 RKP00918.1 - 1.4e-16 60.8 0.0 1.7e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 RasGAP PF00616.19 RKP00920.1 - 1.7e-31 109.5 2.0 4.3e-28 98.5 0.7 3.3 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 RKP00920.1 - 6.1e-11 42.5 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain PH PF00169.29 RKP00920.1 - 5.7e-08 33.2 0.0 1.2e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 PH domain FCH PF00611.23 RKP00920.1 - 0.0011 19.1 0.0 0.004 17.4 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain AAA_6 PF12774.7 RKP00921.1 - 5.7e-158 525.1 0.0 5.6e-157 521.8 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKP00921.1 - 6.5e-134 447.0 5.3 6.5e-134 447.0 5.3 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKP00921.1 - 2.1e-104 349.1 0.0 6.9e-104 347.4 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKP00921.1 - 1.5e-103 345.7 0.2 2.1e-102 341.9 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKP00921.1 - 5.8e-91 303.5 4.1 1.4e-90 302.3 3.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKP00921.1 - 2.9e-71 238.7 3.1 9.3e-69 230.5 0.2 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKP00921.1 - 7.6e-58 194.9 0.0 2.9e-56 189.8 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 RKP00921.1 - 2e-50 171.8 4.9 5.4e-50 170.4 4.9 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RKP00921.1 - 1.3e-45 154.4 0.0 9.5e-43 145.1 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKP00921.1 - 8.4e-20 71.2 0.0 1.9e-06 27.9 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKP00921.1 - 2.8e-18 66.2 0.5 1.3e-17 64.1 0.0 2.5 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKP00921.1 - 3.7e-16 59.2 0.0 2.2e-15 56.7 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 RKP00921.1 - 6.4e-08 33.1 0.1 0.12 12.8 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKP00921.1 - 0.00022 21.5 0.1 2.1 8.6 0.0 4.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 RKP00921.1 - 0.00074 19.9 0.0 3.3 8.2 0.0 3.9 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 RKP00921.1 - 0.00076 19.9 0.3 7.3 6.9 0.0 5.0 4 1 0 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 RKP00921.1 - 0.022 15.3 0.1 1.4 9.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain TPR_5 PF12688.7 RKP00921.1 - 0.035 14.3 2.1 0.14 12.4 0.0 2.7 2 0 0 2 2 2 0 Tetratrico peptide repeat AAA_30 PF13604.6 RKP00921.1 - 0.072 12.8 0.5 3.4 7.4 0.3 2.9 3 0 0 3 3 3 0 AAA domain Latarcin PF10279.9 RKP00921.1 - 0.18 12.2 1.2 34 4.9 0.6 3.2 2 0 0 2 2 2 0 Latarcin precursor AAA_24 PF13479.6 RKP00921.1 - 0.78 9.4 2.3 43 3.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain Ras PF00071.22 RKP00922.1 - 2.8e-24 85.6 0.0 3.8e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RKP00922.1 - 4.9e-18 65.5 0.0 1e-17 64.5 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP00922.1 - 0.00036 20.0 0.0 0.0043 16.5 0.0 2.1 2 1 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RKP00922.1 - 0.018 15.0 0.1 9.8 6.1 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 RKP00922.1 - 0.1 12.7 0.3 0.43 10.6 0.2 2.0 3 0 0 3 3 3 0 Dynamin family AAA_16 PF13191.6 RKP00922.1 - 0.11 12.9 0.7 0.36 11.2 0.7 2.0 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 RKP00922.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 RKP00922.1 - 0.14 12.0 0.2 2.9 7.8 0.2 2.1 2 0 0 2 2 2 0 NACHT domain RhoGAP PF00620.27 RKP00923.1 - 2.6e-38 131.2 0.0 2.8e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF3135 PF11333.8 RKP00923.1 - 0.044 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DnaJ PF00226.31 RKP00924.1 - 4.7e-06 26.6 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 RKP00924.1 - 0.0028 17.7 0.0 0.0029 17.6 0.0 1.0 1 0 0 1 1 1 1 Pam16 DUF2039 PF10217.9 RKP00925.1 - 1.6e-26 92.5 10.2 2.6e-26 91.8 10.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) BUD22 PF09073.10 RKP00925.1 - 0.047 13.0 16.9 0.066 12.6 16.9 1.3 1 0 0 1 1 1 0 BUD22 zinc-ribbons_6 PF07191.12 RKP00925.1 - 0.07 13.1 8.7 0.12 12.3 8.7 1.5 1 0 0 1 1 1 0 zinc-ribbons Cwf_Cwc_15 PF04889.12 RKP00925.1 - 0.29 10.8 16.9 0.44 10.2 16.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cript PF10235.9 RKP00925.1 - 1.6 9.4 11.8 0.67 10.6 8.6 1.9 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DiS_P_DiS PF06750.13 RKP00925.1 - 2.9 8.1 6.8 0.51 10.5 3.1 1.7 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Ephrin_rec_like PF07699.13 RKP00925.1 - 7.7 6.4 8.9 1.2 9.0 0.3 2.8 1 1 1 2 2 2 0 Putative ephrin-receptor like bZIP_1 PF00170.21 RKP00926.1 - 7.3e-10 38.8 6.4 1.2e-09 38.1 6.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RKP00926.1 - 9.2e-06 25.6 7.5 1.5e-05 25.0 7.5 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 RKP00926.1 - 0.068 13.7 3.4 0.11 13.0 3.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.15 RKP00926.1 - 0.36 10.6 0.9 0.62 9.9 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator SRP68 PF16969.5 RKP00927.1 - 3.8e-49 168.1 9.4 7.9e-41 140.7 6.9 2.2 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 Cas3_C PF18395.1 RKP00927.1 - 0.0025 18.3 1.8 0.0081 16.6 0.0 2.7 3 0 0 3 3 3 1 Cas3 C-terminal domain RPA_interact_N PF14766.6 RKP00928.1 - 0.0066 16.0 1.2 0.013 15.1 1.2 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Hydrolase_4 PF12146.8 RKP00929.1 - 2.3e-09 36.9 0.0 3.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 RKP00929.1 - 7.3e-07 28.7 0.0 9.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RKP00929.1 - 1.4e-06 29.1 0.2 4.3e-06 27.5 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RKP00929.1 - 1.4e-05 24.9 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 RKP00929.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.12 RKP00929.1 - 0.016 14.9 0.0 0.035 13.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase RNaseH_pPIWI_RE PF13032.6 RKP00929.1 - 0.029 14.3 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE Peptidase_S9 PF00326.21 RKP00929.1 - 0.064 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1263 PF06882.12 RKP00929.1 - 0.083 12.9 1.5 0.38 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) DUF900 PF05990.12 RKP00929.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.25 RKP00930.1 - 9.8e-44 149.7 0.0 1e-21 77.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP00930.1 - 8.5e-14 51.5 0.0 1.6e-08 34.1 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 RKP00930.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YABBY PF04690.13 RKP00933.1 - 1.5e-16 61.4 1.7 1.6e-16 61.3 1.7 1.0 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 RKP00933.1 - 6.1e-07 30.0 1.2 6.4e-07 30.0 1.2 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 RKP00933.1 - 8.6e-06 26.1 0.9 9.4e-06 26.0 0.9 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKP00933.1 - 0.00025 21.6 0.2 0.00027 21.5 0.2 1.1 1 0 0 1 1 1 1 HMG-box domain GATA PF00320.27 RKP00934.1 - 4.3e-09 35.8 5.6 1.4e-08 34.2 5.6 1.9 1 0 0 1 1 1 1 GATA zinc finger DUF515 PF04415.12 RKP00934.1 - 7.8 4.8 12.4 13 4.0 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) IHABP4_N PF16174.5 RKP00934.1 - 8.5 7.0 8.6 4.2 8.0 0.2 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal PK PF00224.21 RKP00935.1 - 7e-148 492.1 5.6 8.5e-148 491.9 5.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RKP00935.1 - 2.8e-29 101.7 0.1 7.8e-29 100.3 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RKP00935.1 - 0.0013 18.0 0.7 0.0029 16.8 0.7 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family YajC PF02699.15 RKP00935.1 - 0.016 15.0 0.3 0.19 11.6 0.1 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit Cupin_8 PF13621.6 RKP00936.1 - 2.3e-14 53.8 0.1 1.6e-10 41.1 0.0 2.4 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 RKP00936.1 - 5e-12 46.3 0.0 1.8e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 RKP00936.1 - 0.042 13.6 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 RKP00936.1 - 0.089 12.2 0.0 0.42 10.0 0.0 2.0 1 1 0 1 1 1 0 Cupin superfamily protein Elongin_A PF06881.11 RKP00936.1 - 0.13 12.8 0.2 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A SPAM PF02090.15 RKP00937.1 - 0.0058 16.5 5.3 0.043 13.6 0.1 2.3 2 0 0 2 2 2 1 Salmonella surface presentation of antigen gene type M protein MIT PF04212.18 RKP00937.1 - 0.021 14.9 4.7 0.058 13.5 4.7 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain GPS2_interact PF15784.5 RKP00937.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain bZIP_1 PF00170.21 RKP00937.1 - 0.067 13.3 0.3 0.067 13.3 0.3 2.1 2 1 1 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 RKP00937.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein NRBF2_MIT PF17169.4 RKP00937.1 - 0.25 11.6 4.2 0.66 10.2 4.2 1.7 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 SOGA PF11365.8 RKP00937.1 - 0.59 11.3 4.7 1.8 9.8 0.1 2.8 3 0 0 3 3 3 0 Protein SOGA Ntox1 PF15500.6 RKP00937.1 - 0.93 9.9 5.4 4.3 7.7 0.6 2.8 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 PRKG1_interact PF15898.5 RKP00937.1 - 3.2 8.7 6.6 53 4.8 2.0 3.2 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 RKP00937.1 - 8.5 5.7 9.9 4.2 6.7 1.7 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PAP2 PF01569.21 RKP00938.1 - 3.3e-10 39.9 11.6 5e-10 39.3 7.6 2.6 1 1 1 2 2 2 1 PAP2 superfamily DUF1538 PF07556.11 RKP00938.1 - 0.025 13.9 0.3 0.025 13.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) DUF212 PF02681.14 RKP00938.1 - 0.3 11.2 2.5 0.51 10.5 0.3 2.4 1 1 1 2 2 2 0 Divergent PAP2 family DUF2070 PF09843.9 RKP00938.1 - 1.4 7.2 3.5 1.9 6.7 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DoxX_2 PF13564.6 RKP00938.1 - 3.6 7.8 21.0 3.5 7.8 0.0 3.2 1 1 2 3 3 3 0 DoxX-like family tRNA_lig_CPD PF08302.11 RKP00939.1 - 4.6e-05 23.0 0.0 9.5e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 RKP00939.1 - 0.00023 21.3 0.0 0.0032 17.6 0.0 2.3 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_28 PF13521.6 RKP00939.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RKP00939.1 - 0.069 13.7 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Chibby PF14645.6 RKP00941.1 - 0.00044 20.6 0.0 0.00066 20.1 0.0 1.2 1 0 0 1 1 1 1 Chibby family RSRP PF17069.5 RKP00941.1 - 0.56 9.7 13.9 0.83 9.2 13.9 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 zf-C2H2 PF00096.26 RKP00942.1 - 4.6e-14 52.0 6.3 2.1e-06 27.8 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP00942.1 - 8e-12 44.9 5.6 4e-05 24.1 0.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP00942.1 - 4.3e-07 30.1 10.9 0.00021 21.6 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HC_2 PF13913.6 RKP00942.1 - 7.8e-07 28.8 7.5 1.5e-05 24.7 0.3 2.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 RKP00942.1 - 2.5e-06 27.4 1.9 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKP00942.1 - 0.001 19.3 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP00942.1 - 0.0013 19.1 0.2 0.055 13.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RKP00942.1 - 0.0092 16.3 0.3 1.7 9.1 0.1 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 RKP00942.1 - 0.032 13.8 0.1 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_3rep PF18868.1 RKP00942.1 - 0.074 13.7 2.6 2.3 8.9 0.7 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RKP00942.1 - 0.45 10.3 6.3 6 6.7 0.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RKP00942.1 - 1.8 8.4 10.1 8.3 6.3 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Carn_acyltransf PF00755.20 RKP00943.1 - 2.3e-141 472.3 0.0 2.8e-141 472.0 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MEA1 PF06910.11 RKP00944.1 - 9.1e-08 32.8 5.8 2.5e-07 31.4 5.8 1.7 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) DNA_pol_phi PF04931.13 RKP00944.1 - 0.075 11.1 4.0 0.091 10.9 4.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 RKP00944.1 - 0.16 12.1 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 RKP00944.1 - 0.26 9.5 1.7 0.33 9.2 1.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 RKP00944.1 - 0.45 8.6 2.7 0.48 8.5 2.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 RKP00944.1 - 0.64 9.3 3.2 0.75 9.1 3.2 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 RKP00944.1 - 6.9 5.9 13.3 8.8 5.5 13.3 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 RKP00944.1 - 8.1 4.5 6.0 9.9 4.2 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 RKP00944.1 - 8.4 6.0 10.3 12 5.6 10.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3395 PF11875.8 RKP00945.1 - 7.5e-34 116.9 0.0 1.4e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 RKP00945.1 - 2.3e-18 66.0 0.1 4.4e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain HAP1_N PF04849.13 RKP00946.1 - 0.0073 15.6 1.4 0.0073 15.6 1.4 4.5 4 1 1 5 5 5 2 HAP1 N-terminal conserved region Takusan PF04822.13 RKP00946.1 - 1.1 9.3 5.2 1.1 9.2 0.0 3.3 3 0 0 3 3 3 0 Takusan TSC22 PF01166.18 RKP00946.1 - 1.3 9.4 12.6 0.36 11.2 0.4 4.4 4 1 0 4 4 4 0 TSC-22/dip/bun family PX PF00787.24 RKP00947.1 - 3.3e-23 81.8 1.3 1.1e-22 80.1 0.0 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 RKP00947.1 - 6.7e-15 55.3 5.5 9.8e-10 38.4 2.9 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 RKP00947.1 - 0.0014 18.1 1.1 0.034 13.6 0.1 2.2 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 RKP00947.1 - 0.0098 15.6 7.6 0.31 10.7 7.0 2.2 1 1 0 1 1 1 1 BAR domain of APPL family DUF5095 PF17016.5 RKP00947.1 - 0.051 13.3 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Xpo1 PF08389.12 RKP00948.1 - 0.015 15.4 0.0 0.35 10.9 0.0 2.8 2 0 0 2 2 2 0 Exportin 1-like protein IBN_N PF03810.19 RKP00948.1 - 0.03 14.2 0.0 0.29 11.1 0.0 2.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain UMPH-1 PF05822.12 RKP00950.1 - 7.5e-60 202.5 0.0 9.3e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RKP00950.1 - 8.4e-12 45.9 0.3 1.6e-11 45.0 0.3 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cyclin_C PF02984.19 RKP00951.1 - 1.5e-27 96.1 0.2 1.5e-27 96.1 0.2 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 RKP00951.1 - 9.8e-25 86.7 1.2 1.6e-24 86.1 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_60s PF00428.19 RKP00951.1 - 0.0077 16.8 3.0 0.02 15.4 3.0 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein PsbW PF07123.12 RKP00951.1 - 0.052 13.6 0.8 0.43 10.6 0.2 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) ADP_PFK_GK PF04587.15 RKP00951.1 - 1.7 7.2 6.1 0.74 8.3 3.5 1.6 2 0 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Mgm101p PF06420.12 RKP00952.1 - 2.3e-09 37.0 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial genome maintenance MGM101 Response_reg PF00072.24 RKP00953.1 - 3.6e-18 65.7 0.5 4e-18 65.6 0.5 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.17 RKP00954.1 - 7.7e-28 97.0 5.8 1.3e-27 96.3 5.8 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ribosomal_S2 PF00318.20 RKP00955.1 - 8.6e-51 172.2 0.2 4.6e-25 88.1 0.5 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 ERCC4 PF02732.15 RKP00956.1 - 1.2e-17 64.6 0.0 2.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 RKP00956.1 - 0.0042 17.7 0.0 0.0099 16.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 RKP00956.1 - 0.0073 16.4 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif ABC2_membrane PF01061.24 RKP00957.1 - 1.1e-70 237.3 47.2 3.7e-38 131.1 13.4 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 RKP00957.1 - 5.7e-35 120.8 0.4 1.5e-17 64.4 0.0 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 RKP00957.1 - 7.6e-23 80.2 2.9 5.9e-17 61.4 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter AAA_21 PF13304.6 RKP00957.1 - 9.2e-07 29.0 0.1 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKP00957.1 - 3.6e-06 26.6 0.2 0.00096 18.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RKP00957.1 - 4.5e-06 27.1 1.0 0.0034 17.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 RKP00957.1 - 6.9e-05 22.1 18.1 6.9e-05 22.1 18.1 3.3 2 2 0 2 2 1 1 ABC-2 family transporter protein AAA_25 PF13481.6 RKP00957.1 - 0.00013 21.6 0.2 0.046 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 RKP00957.1 - 0.00046 20.1 0.1 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 RKP00957.1 - 0.0022 18.5 0.6 0.036 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RKP00957.1 - 0.0028 17.7 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 RKP00957.1 - 0.0052 17.0 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 RKP00957.1 - 0.0061 16.0 0.0 3.3 7.1 0.0 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 RKP00957.1 - 0.012 15.0 0.3 0.57 9.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 RKP00957.1 - 0.021 15.1 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RKP00957.1 - 0.037 13.8 0.1 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RKP00957.1 - 0.045 13.7 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 RKP00957.1 - 0.091 13.3 0.2 2.4 8.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 RKP00957.1 - 0.11 11.7 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 RKP00957.1 - 0.14 12.1 0.1 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 RKP00957.1 - 0.23 11.8 0.6 4.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 RKP00957.1 - 2 8.2 7.8 0.17 11.6 0.7 2.9 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Promethin PF16015.5 RKP00958.1 - 2.2e-05 24.3 10.8 4.4e-05 23.4 10.8 1.5 1 0 0 1 1 1 1 Promethin zf-C3HC4 PF00097.25 RKP00959.1 - 1.9e-09 37.2 5.5 2.8e-09 36.7 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKP00959.1 - 1.9e-09 37.2 3.1 2.8e-09 36.7 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP00959.1 - 7.7e-09 35.3 7.5 1.2e-08 34.6 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKP00959.1 - 1.2e-07 31.9 8.1 1.9e-07 31.3 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RKP00959.1 - 1.4e-07 31.7 3.7 2.5e-07 30.9 3.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKP00959.1 - 1.8e-07 31.0 4.3 2.7e-07 30.4 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKP00959.1 - 5.7e-07 29.5 1.7 5.7e-07 29.5 1.7 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RKP00959.1 - 1.9e-05 24.4 6.3 3.1e-05 23.7 6.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RKP00959.1 - 0.0011 18.9 1.4 0.002 18.2 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 RKP00959.1 - 0.011 15.9 8.6 0.017 15.3 8.6 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Siva PF05458.12 RKP00959.1 - 0.016 14.9 1.4 0.024 14.3 1.4 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_10 PF16685.5 RKP00959.1 - 0.034 14.3 4.0 0.065 13.4 4.0 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 RKP00959.1 - 0.085 12.8 3.2 0.12 12.3 3.2 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_11 PF17123.5 RKP00959.1 - 0.11 12.3 5.1 0.22 11.3 5.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 RKP00959.1 - 0.13 12.1 7.2 0.23 11.3 7.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 RKP00959.1 - 0.25 11.0 2.8 0.52 10.0 2.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_5 PF17121.5 RKP00959.1 - 0.51 10.3 6.3 2.9 7.8 6.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RKP00959.1 - 0.65 9.9 4.6 1.3 9.0 4.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein GTP_EFTU PF00009.27 RKP00960.1 - 4e-25 88.5 0.0 7.1e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 RKP00960.1 - 7.5e-19 67.8 0.0 2e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 RKP00960.1 - 2e-13 50.5 0.3 1.1e-09 38.5 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 RKP00960.1 - 3.2e-11 43.0 0.0 8.4e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 RKP00960.1 - 0.015 15.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 RKP00960.1 - 0.022 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mgm101p PF06420.12 RKP00961.1 - 1.2e-63 213.6 0.0 1.3e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 FragX_IP PF05994.11 RKP00962.1 - 1.8e-178 595.4 0.0 2.9e-177 591.4 0.0 2.0 1 1 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 RKP00962.1 - 1.3e-11 44.4 0.1 2.3e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF3676 PF12429.8 RKP00962.1 - 0.021 14.7 0.2 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) Rotamase_2 PF13145.6 RKP00962.1 - 1.7 9.5 6.3 5.8 7.8 0.5 2.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain Ran_BP1 PF00638.18 RKP00963.1 - 1.1e-49 167.7 0.1 1.4e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RKP00963.1 - 8.3e-05 22.5 0.0 0.00049 20.0 0.0 1.9 1 1 0 1 1 1 1 WH1 domain Chlorosome_CsmC PF11098.8 RKP00964.1 - 0.39 10.7 3.8 0.6 10.1 3.8 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF5536 PF17688.1 RKP00964.1 - 0.4 10.5 8.1 0.65 9.9 8.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5536) PHD PF00628.29 RKP00965.1 - 8.1e-08 32.0 8.4 9.8e-08 31.8 8.4 1.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKP00965.1 - 0.0041 16.6 1.7 0.0069 15.9 1.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RKP00965.1 - 0.0085 16.3 4.4 0.01 16.1 4.4 1.3 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-C4pol PF14260.6 RKP00965.1 - 0.092 13.2 1.2 0.092 13.2 1.2 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CorA PF01544.18 RKP00966.1 - 4.1e-51 174.0 2.0 5e-51 173.7 2.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Plasmid_stab_B PF10784.9 RKP00966.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Plasmid stability protein Vps62 PF06101.11 RKP00967.1 - 1.3e-15 56.7 1.4 2.4e-11 42.6 0.1 3.0 3 0 0 3 3 3 3 Vacuolar protein sorting-associated protein 62 THP2 PF09432.10 RKP00968.1 - 0.0032 17.5 0.1 0.067 13.2 0.0 3.4 3 0 0 3 3 3 1 Tho complex subunit THP2 PUF PF00806.19 RKP00969.1 - 2.6e-65 212.6 9.7 6.3e-09 35.0 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 RKP00969.1 - 0.043 13.7 3.4 22 4.8 0.0 5.0 5 1 1 6 6 6 0 Single Cache domain 2 DHFR_1 PF00186.19 RKP00971.1 - 2.9e-29 101.8 0.0 1.6e-09 37.7 0.0 3.0 3 0 0 3 3 3 3 Dihydrofolate reductase Peptidase_C3G PF12381.8 RKP00972.1 - 0.12 11.9 0.6 0.15 11.5 0.6 1.1 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase Malate_synthase PF01274.22 RKP00973.1 - 1.5e-217 723.0 0.0 1.8e-217 722.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 RKP00973.1 - 0.0035 16.5 0.0 0.12 11.5 0.0 2.7 3 1 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family RNase_PH PF01138.21 RKP00976.1 - 1.1e-18 68.0 0.0 1.7e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RKP00976.1 - 0.00014 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3128 PF11326.8 RKP00977.1 - 1.6e-16 60.4 1.5 1.8e-16 60.3 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Hid1 PF12722.7 RKP00978.1 - 2.1e-179 598.4 0.0 1.3e-154 516.4 0.0 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 RKP00978.1 - 7.1e-118 394.7 0.0 8.8e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein BNIP3 PF06553.12 RKP00978.1 - 0.12 12.0 2.2 0.21 11.3 2.2 1.3 1 0 0 1 1 1 0 BNIP3 DUF3969 PF13108.6 RKP00979.1 - 0.026 14.6 0.6 0.062 13.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) DUF4094 PF13334.6 RKP00979.1 - 0.12 12.8 4.5 1.7 9.1 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) MRPL52 PF18699.1 RKP00979.1 - 3.6 7.8 8.6 1.9 8.7 2.7 2.8 2 0 0 2 2 2 0 Mitoribosomal protein mL52 bZIP_2 PF07716.15 RKP00979.1 - 9.9 6.3 8.9 2.3 8.4 3.4 2.8 2 0 0 2 2 2 0 Basic region leucine zipper FCH PF00611.23 RKP00980.1 - 6.2e-18 64.9 6.0 2e-17 63.3 5.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 RKP00980.1 - 2.3e-10 39.9 0.1 4.7e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP00980.1 - 5.1e-06 26.2 0.2 1.1e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP00980.1 - 1.6e-05 24.5 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 RKP00980.1 - 0.001 19.3 0.1 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain DUF2956 PF11169.8 RKP00980.1 - 0.004 17.3 2.7 0.004 17.3 2.7 2.9 2 1 2 4 4 4 1 Protein of unknown function (DUF2956) DUF4188 PF13826.6 RKP00980.1 - 2.7 8.4 5.2 4.3 7.7 1.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4188) POX PF07526.11 RKP00980.1 - 5.1 7.7 12.9 3.9 8.1 8.5 2.7 1 1 1 2 2 2 0 Associated with HOX Fer4 PF00037.27 RKP00981.1 - 1.8e-15 56.0 17.2 3.6e-09 36.1 4.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 RKP00981.1 - 4.5e-14 52.8 10.9 7.7e-14 52.0 10.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 RKP00981.1 - 6.1e-12 46.3 6.4 7.2e-06 26.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 RKP00981.1 - 3e-11 43.3 3.8 3.7e-05 23.7 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 RKP00981.1 - 1.4e-10 41.1 21.1 3.5e-07 30.2 12.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 RKP00981.1 - 2e-09 37.5 10.6 3.3e-09 36.8 10.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 RKP00981.1 - 1.5e-08 34.9 18.9 4.3e-05 23.9 12.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 RKP00981.1 - 5.1e-08 32.7 17.5 0.00013 21.8 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 RKP00981.1 - 9.6e-08 31.7 12.5 0.0014 18.6 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 RKP00981.1 - 4.6e-06 26.7 10.7 0.00045 20.5 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 RKP00981.1 - 1.3e-05 25.6 11.6 0.0011 19.4 12.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 RKP00981.1 - 0.0012 19.7 17.6 0.0095 16.8 4.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 RKP00981.1 - 0.0021 18.5 14.3 0.14 12.7 2.6 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 RKP00981.1 - 0.0052 17.0 5.2 0.3 11.3 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 RKP00981.1 - 0.0075 16.5 9.2 1.5 9.1 1.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain ETF_QO PF05187.13 RKP00981.1 - 0.11 12.6 5.8 0.85 9.8 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 RKP00981.1 - 0.13 13.1 11.6 1.1 10.1 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain EPF PF17181.4 RKP00981.1 - 0.21 11.6 5.4 0.14 12.1 0.7 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins LRR_6 PF13516.6 RKP00982.1 - 2e-06 27.4 0.1 1.2 9.3 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 RKP00982.1 - 0.0027 18.0 0.0 15 6.6 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 RKP00982.1 - 0.027 14.9 0.2 2.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF5330 PF17264.2 RKP00982.1 - 0.061 13.4 0.0 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5330) KH_1 PF00013.29 RKP00983.1 - 1.5e-42 143.2 8.6 3.3e-16 58.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RKP00983.1 - 2.7e-09 36.7 7.8 0.006 16.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RKP00983.1 - 2.3e-07 30.6 2.7 0.0057 16.5 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 RKP00983.1 - 0.01 15.9 5.8 6.8 6.9 0.3 3.3 3 0 0 3 3 3 0 NusA-like KH domain DUF3584 PF12128.8 RKP00983.1 - 0.37 8.2 4.3 0.5 7.8 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.11 RKP00985.1 - 1.2e-18 67.5 0.4 6.3e-18 65.2 0.1 2.1 1 1 1 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 RKP00985.1 - 9e-08 32.0 3.2 9e-08 32.0 3.2 2.6 3 1 1 4 4 4 1 SNARE domain DUF3135 PF11333.8 RKP00985.1 - 0.00088 19.5 1.4 0.0016 18.6 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) Use1 PF09753.9 RKP00985.1 - 0.0015 18.4 2.0 0.0016 18.2 2.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF745 PF05335.13 RKP00985.1 - 0.0025 17.6 2.8 0.0025 17.6 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF745) Uso1_p115_C PF04871.13 RKP00985.1 - 0.0067 16.8 1.1 0.0099 16.2 0.8 1.4 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 RKP00985.1 - 0.017 13.1 1.7 0.021 12.8 1.7 1.2 1 0 0 1 1 1 0 Prominin DUF1054 PF06335.12 RKP00985.1 - 0.048 13.6 0.3 0.065 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) MFS_Mycoplasma PF07672.13 RKP00985.1 - 0.093 12.0 3.3 0.15 11.3 3.3 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2207 PF09972.9 RKP00985.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EMP24_GP25L PF01105.24 RKP00985.1 - 0.47 10.4 7.4 1.5 8.7 2.6 2.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 RKP00985.1 - 0.52 10.6 2.8 0.76 10.1 1.2 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 SlyX PF04102.12 RKP00985.1 - 5.3 7.7 14.5 1.8 9.3 6.8 3.2 3 1 1 4 4 4 0 SlyX WD40 PF00400.32 RKP00986.1 - 0.00019 22.2 0.2 0.22 12.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat BolA PF01722.18 RKP00987.1 - 2.5e-11 43.7 0.0 8.9e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein TFIID-31kDa PF02291.15 RKP00988.1 - 4.2e-44 149.5 0.0 4.6e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RKP00988.1 - 4.5e-07 29.8 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 RKP00988.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 RKP00988.1 - 0.00023 21.5 0.1 0.00029 21.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RKP00988.1 - 0.00053 20.1 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_lid_2 PF17863.1 RKP00988.1 - 0.013 15.3 0.3 0.019 14.8 0.3 1.2 1 0 0 1 1 1 0 AAA lid domain TIP49_C PF17856.1 RKP00988.1 - 0.074 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 AAA-lid domain TFIID-18kDa PF02269.16 RKP00988.1 - 0.088 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1931 PF09123.11 RKP00988.1 - 0.099 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Tubulin PF00091.25 RKP00989.1 - 1.2e-31 110.5 0.0 1.8e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 RKP00989.1 - 0.01 15.1 0.1 0.047 12.9 0.2 1.9 1 1 1 2 2 2 0 Tubulin like EF-hand_1 PF00036.32 RKP00990.1 - 3.1e-17 60.7 1.7 3.1e-07 29.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RKP00990.1 - 8.7e-14 50.2 1.3 6.2e-07 28.8 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RKP00990.1 - 4.1e-12 46.4 0.3 6.4e-12 45.7 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RKP00990.1 - 8.1e-12 44.1 1.1 1.5e-05 24.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RKP00990.1 - 1.5e-11 44.0 4.2 1.1e-07 31.6 0.6 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 RKP00990.1 - 1.5e-05 25.2 0.1 5.1e-05 23.5 0.0 1.8 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 RKP00990.1 - 0.018 15.0 0.0 0.58 10.1 0.0 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-C2H2 PF00096.26 RKP00991.1 - 1.9e-11 43.7 6.1 8.4e-05 22.8 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP00991.1 - 7e-10 38.9 4.9 0.00017 22.1 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP00991.1 - 3.7e-09 36.6 9.2 3.3e-07 30.4 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RKP00991.1 - 5.3e-08 32.9 0.0 0.0076 16.5 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP00991.1 - 8.5e-07 28.8 1.2 0.006 16.5 0.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 RKP00991.1 - 1.8e-06 28.1 0.5 0.042 14.3 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 RKP00991.1 - 1.2e-05 24.9 2.4 0.05 13.4 0.5 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 RKP00991.1 - 0.026 14.6 2.5 0.089 12.9 1.6 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 RKP00991.1 - 0.049 13.7 0.9 0.8 9.8 0.3 2.1 1 1 1 2 2 2 0 BED zinc finger GAGA PF09237.11 RKP00991.1 - 0.059 13.2 2.0 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 GAGA factor C1_1 PF00130.22 RKP00991.1 - 0.12 12.3 2.7 0.3 11.0 0.6 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C5HCH PF17982.1 RKP00991.1 - 0.14 12.4 3.9 0.16 12.2 1.6 2.0 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2HE PF16278.5 RKP00991.1 - 0.18 12.3 2.0 4.2 7.9 0.3 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 RKP00991.1 - 2.6 7.9 6.6 2.4 8.0 2.2 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Methyltransf_16 PF10294.9 RKP00993.1 - 8.2e-11 41.9 0.0 4.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 RKP00993.1 - 0.13 11.8 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Ribosomal_L1 PF00687.21 RKP00995.1 - 4.3e-44 150.7 2.4 5.2e-44 150.4 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Tnp_22_trimer PF17489.2 RKP00995.1 - 0.071 13.1 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 L1 transposable element trimerization domain Lactamase_B_6 PF16661.5 RKP00996.1 - 2.2e-53 180.6 0.0 3.4e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 RKP00996.1 - 2.7e-16 60.2 0.0 9.1e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 RKP00996.1 - 9.8e-12 45.1 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 RKP00996.1 - 1.5e-06 28.0 0.0 3.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 RKP00996.1 - 6.9e-06 25.7 1.5 1.7e-05 24.4 1.5 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RKP00996.1 - 1.9e-05 24.8 5.0 2.8e-05 24.2 2.6 2.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF3474 PF11960.8 RKP00996.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Lactamase_B_3 PF13483.6 RKP00996.1 - 0.15 11.9 0.1 0.96 9.3 0.1 2.2 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Cwf_Cwc_15 PF04889.12 RKP00996.1 - 4 7.1 8.8 4.2 7.0 6.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Vps51 PF08700.11 RKP00997.1 - 5.1e-18 64.9 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 RKP00997.1 - 1e-06 27.7 0.7 1.7e-06 27.0 0.7 1.2 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 RKP00997.1 - 6.6e-06 26.1 0.0 9.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 RKP00997.1 - 0.0065 16.6 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 RKP00997.1 - 0.015 15.5 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Zw10 PF06248.13 RKP00997.1 - 0.098 11.2 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Sec8_exocyst PF04048.14 RKP00997.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Snapin_Pallidin PF14712.6 RKP00997.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Vps53_N PF04100.12 RKP00997.1 - 0.13 11.2 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF664 PF04978.12 RKP00997.1 - 4.2 7.8 8.0 1.6 9.2 1.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF664) Utp11 PF03998.13 RKP00998.1 - 2.9e-67 227.2 16.0 3.3e-67 227.0 16.0 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 RKP00998.1 - 0.041 13.2 0.4 0.065 12.5 0.4 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2278 PF10042.9 RKP00998.1 - 0.071 13.1 0.9 0.11 12.5 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) PSK_trans_fac PF07704.11 RKP00998.1 - 4.7 8.0 11.8 0.18 12.6 1.5 2.9 3 1 0 3 3 3 0 Rv0623-like transcription factor SIP1 PF04938.12 RKP00999.1 - 3.6e-16 59.6 0.0 1.2e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) ER_lumen_recept PF00810.18 RKP01000.1 - 1.8e-14 54.8 4.0 2.8e-14 54.2 4.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor MnhB PF04039.13 RKP01000.1 - 0.088 13.1 1.3 1.6 9.1 0.4 2.2 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF4448 PF14610.6 RKP01002.1 - 0.0055 16.5 0.3 0.0084 15.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 RKP01002.1 - 0.019 15.8 0.0 0.057 14.3 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 RKP01002.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Stevor PF17410.2 RKP01002.1 - 0.07 12.7 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Apt1 PF10351.9 RKP01002.1 - 0.34 9.7 4.5 0.42 9.4 4.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF202 PF02656.15 RKP01002.1 - 7.2 7.1 7.4 0.33 11.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SPX PF03105.19 RKP01002.1 - 7.5 6.4 16.3 11 5.8 16.3 1.3 1 0 0 1 1 1 0 SPX domain MAP65_ASE1 PF03999.12 RKP01003.1 - 0.046 12.4 0.3 0.062 12.0 0.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Nas2_N PF18265.1 RKP01004.1 - 3.2e-27 94.3 0.1 4.2e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 RKP01004.1 - 1.7e-06 27.8 0.4 8.5e-05 22.3 0.4 2.7 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RKP01004.1 - 0.004 17.4 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 RKP01004.1 - 0.0057 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Radical_SAM_C PF16199.5 RKP01005.1 - 2.9e-32 110.5 0.1 2.1e-31 107.7 0.0 2.3 2 1 1 3 3 3 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 RKP01005.1 - 9.5e-18 65.1 0.1 4e-17 63.1 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 RKP01005.1 - 9.9e-10 38.7 0.0 2.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RKP01005.1 - 6.8e-05 22.8 0.0 0.00018 21.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKP01005.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 RKP01006.1 - 4.6e-68 229.5 0.0 5.3e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01006.1 - 1.5e-29 103.1 0.0 1.9e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01006.1 - 1.6e-10 40.7 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP01006.1 - 0.0031 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP01006.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain 5-FTHF_cyc-lig PF01812.20 RKP01007.1 - 1.5e-30 106.4 0.0 2.1e-29 102.7 0.0 2.0 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SNF2_N PF00176.23 RKP01008.1 - 1.2e-25 90.0 0.0 1.9e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKP01008.1 - 2e-14 53.8 0.0 4.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP01008.1 - 0.00029 20.9 0.0 0.038 14.0 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKP01008.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 RKP01008.1 - 0.011 15.5 0.1 0.19 11.5 0.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase PX PF00787.24 RKP01009.1 - 3.3e-06 27.1 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 PX domain PAP2 PF01569.21 RKP01010.1 - 7.5e-22 77.6 8.4 7.5e-22 77.6 8.4 2.8 3 1 1 4 4 4 1 PAP2 superfamily PAP2_3 PF14378.6 RKP01010.1 - 2.9 7.6 21.6 3.5 7.3 18.0 3.0 1 1 1 2 2 2 0 PAP2 superfamily SET PF00856.28 RKP01011.1 - 0.1 12.9 0.0 0.42 11.0 0.1 1.8 1 1 0 1 1 1 0 SET domain 4HBT PF03061.22 RKP01012.1 - 1.2e-12 48.0 0.0 2.1e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 RKP01012.1 - 2.9e-11 43.9 0.0 3.5e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 RKP01012.1 - 0.0011 18.3 0.2 0.004 16.5 0.8 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase GTP_EFTU PF00009.27 RKP01013.1 - 3e-66 222.7 0.2 7.1e-66 221.4 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RKP01013.1 - 2.5e-30 104.7 0.0 5.9e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 RKP01013.1 - 1.5e-21 76.2 0.0 4.9e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKP01013.1 - 8.2e-14 51.8 0.0 6.1e-13 49.0 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RKP01013.1 - 2.4e-12 46.8 0.0 5.3e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 RKP01013.1 - 0.00044 20.3 0.2 0.00096 19.2 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4347 PF14252.6 RKP01013.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) TetR_C_25 PF17933.1 RKP01013.1 - 0.14 12.5 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IPK PF03770.16 RKP01014.1 - 8.2e-26 91.1 0.1 6.3e-20 71.9 0.0 2.1 1 1 1 2 2 2 2 Inositol polyphosphate kinase PIGA PF08288.12 RKP01017.1 - 2.7e-42 143.2 2.0 3.3e-42 143.0 0.9 1.7 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 RKP01017.1 - 2.6e-31 108.9 1.6 6.2e-31 107.7 1.6 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RKP01017.1 - 7.1e-26 90.8 0.0 1.1e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RKP01017.1 - 1.2e-20 74.3 0.1 2.4e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RKP01017.1 - 7.4e-14 52.5 0.3 1.5e-13 51.5 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RKP01017.1 - 1.6e-05 25.2 0.3 0.00071 19.9 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 RKP01017.1 - 5.5e-05 23.2 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 RKP01017.1 - 0.004 16.9 0.5 0.012 15.3 0.4 1.8 1 1 1 2 2 2 1 Starch synthase catalytic domain UPF0220 PF05255.11 RKP01017.1 - 0.1 12.1 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) zf-C2H2 PF00096.26 RKP01020.1 - 2.1e-12 46.7 12.8 0.00036 20.8 0.4 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKP01020.1 - 7.4e-09 35.6 3.8 4.5e-05 23.7 0.1 3.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKP01020.1 - 3.2e-08 33.7 11.7 0.005 17.6 0.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RKP01020.1 - 1.9e-07 30.9 11.1 2.6e-05 24.1 0.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-LYAR PF08790.11 RKP01020.1 - 3.4e-05 23.6 1.5 0.042 13.8 0.0 3.0 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf-met PF12874.7 RKP01020.1 - 8.3e-05 22.8 0.8 1.1 9.7 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 RKP01020.1 - 0.0025 17.9 4.7 2.3 8.4 0.3 3.1 1 1 2 3 3 3 3 Zinc ribbon domain zf-C2H2_8 PF15909.5 RKP01020.1 - 0.0043 17.3 3.3 0.006 16.9 0.6 1.9 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 RKP01020.1 - 0.0044 17.4 4.5 3 8.4 0.4 3.0 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 RKP01020.1 - 0.01 16.0 2.0 2.9 8.1 0.1 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger HalOD2 PF18547.1 RKP01020.1 - 0.019 14.9 0.7 0.031 14.2 0.7 1.4 1 0 0 1 1 1 0 Halobacterial output domain 2 zf_C2H2_ZHX PF18387.1 RKP01020.1 - 0.019 14.6 3.9 0.59 9.8 0.1 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 RKP01020.1 - 0.034 14.5 1.9 20 5.6 0.2 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 RKP01020.1 - 0.071 13.8 2.5 3.3 8.4 0.5 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats HypA PF01155.19 RKP01020.1 - 0.079 13.0 0.8 0.095 12.7 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_11 PF16622.5 RKP01020.1 - 0.13 12.0 0.2 0.13 12.0 0.2 3.3 3 1 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 RKP01020.1 - 2.1 8.3 8.7 1.5 8.8 0.6 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 RKP01020.1 - 5.4 7.0 9.6 1.8 8.6 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 RKP01021.1 - 2.6e-19 69.2 45.5 2.4e-11 43.7 6.2 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 RKP01021.1 - 0.0016 18.7 2.9 0.0016 18.7 2.9 3.8 3 0 0 3 3 3 2 Ring finger domain UBA_4 PF14555.6 RKP01021.1 - 0.0023 17.7 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain zf-C3HC4 PF00097.25 RKP01021.1 - 0.0034 17.2 3.3 0.0034 17.2 3.3 4.5 3 2 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP01021.1 - 0.03 14.3 0.7 0.03 14.3 0.7 4.3 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RKP01021.1 - 6.4 6.7 40.7 0.27 11.1 3.8 4.8 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) VMA21 PF09446.10 RKP01022.1 - 1.5e-08 34.6 9.2 3.3e-08 33.5 9.2 1.6 1 1 0 1 1 1 1 VMA21-like domain DEAD PF00270.29 RKP01023.1 - 3.9e-45 153.8 0.1 6.6e-45 153.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01023.1 - 1.2e-28 99.6 2.4 1.9e-28 99.0 0.7 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Phage_integrase PF00589.22 RKP01023.1 - 0.011 15.5 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 0 Phage integrase family Phosducin PF02114.16 RKP01025.1 - 2.1e-12 46.5 0.1 3.7e-12 45.8 0.1 1.3 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 RKP01025.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2870 PF11069.8 RKP01025.1 - 0.018 15.4 3.5 0.075 13.4 3.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) UPF0154 PF03672.13 RKP01025.1 - 0.24 11.4 1.9 0.43 10.6 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Pkinase PF00069.25 RKP01026.1 - 3.5e-24 85.6 0.0 4.4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01026.1 - 7e-10 38.6 0.0 1.3e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP01026.1 - 0.00025 19.9 0.0 0.00032 19.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 RKP01026.1 - 0.015 15.5 0.0 0.045 13.9 0.0 1.8 2 0 0 2 2 2 0 ABC1 family APH PF01636.23 RKP01026.1 - 0.029 14.3 0.3 0.5 10.2 0.1 2.4 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 RKP01026.1 - 0.037 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP01026.1 - 0.11 11.7 0.0 7.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SNase PF00565.17 RKP01027.1 - 1.5e-48 163.8 0.0 3.5e-17 62.8 0.0 4.7 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 RKP01027.1 - 1e-22 80.5 0.1 6.7e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Tudor domain SPOR PF05036.13 RKP01027.1 - 0.0028 18.0 0.7 0.044 14.2 0.0 3.2 3 0 0 3 3 3 1 Sporulation related domain Agenet PF05641.12 RKP01027.1 - 0.054 14.0 1.5 11 6.6 0.0 3.3 4 0 0 4 4 4 0 Agenet domain BIR PF00653.21 RKP01028.1 - 0.00016 22.2 2.4 0.0005 20.7 0.4 2.3 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain PPV_E2_C PF00511.17 RKP01028.1 - 0.2 11.9 0.1 0.6 10.3 0.1 1.9 1 0 0 1 1 1 0 E2 (early) protein, C terminal TLD PF07534.16 RKP01029.1 - 3.2e-17 63.1 0.0 3.7e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 TLD ubiquitin PF00240.23 RKP01030.1 - 5.5e-17 61.3 0.1 2.1e-16 59.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family UBA PF00627.31 RKP01030.1 - 1.3e-10 41.0 0.9 1.3e-10 41.0 0.9 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 RKP01030.1 - 6.9e-08 32.6 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 RKP01030.1 - 9.7e-05 22.3 0.1 0.00045 20.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RKP01030.1 - 0.00098 18.9 0.0 0.004 16.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 RKP01030.1 - 0.0014 18.5 28.8 0.14 12.1 21.9 4.1 2 1 1 3 3 3 1 STI1 domain Ubiquitin_2 PF14560.6 RKP01030.1 - 0.0037 17.7 0.1 0.0094 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 RKP01030.1 - 0.065 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 RKP01030.1 - 0.083 13.3 0.1 0.36 11.2 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 RKP01030.1 - 0.67 9.9 11.1 0.23 11.4 7.4 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain XPC-binding PF09280.11 RKP01030.1 - 0.91 9.3 17.4 21 4.9 16.0 3.3 2 1 0 2 2 2 0 XPC-binding domain Sporozoite_P67 PF05642.11 RKP01030.1 - 4.9 5.1 11.8 2.5 6.1 4.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ribosomal_S16 PF00886.19 RKP01031.1 - 5.6e-21 74.4 0.1 6.9e-21 74.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Cwf_Cwc_15 PF04889.12 RKP01032.1 - 2.3 7.9 8.4 4.4 7.0 8.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPR_2 PF13041.6 RKP01033.1 - 0.025 14.8 0.1 29 5.0 0.0 4.2 4 1 1 5 5 5 0 PPR repeat family PPR PF01535.20 RKP01033.1 - 0.21 11.9 0.6 23 5.5 0.1 3.0 2 0 0 2 2 2 0 PPR repeat DUF3845 PF12956.7 RKP01034.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure Na_H_Exchanger PF00999.21 RKP01035.1 - 9.2e-57 192.5 45.6 1.2e-56 192.2 45.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CHS5_N PF16892.5 RKP01036.1 - 0.42 10.6 2.6 9.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Chitin biosynthesis protein CHS5 N-terminus Sin3a_C PF16879.5 RKP01037.1 - 3.1e-64 217.4 0.0 3.1e-64 217.4 0.0 2.3 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 RKP01037.1 - 5.8e-46 154.4 2.5 4.1e-18 65.2 2.1 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 RKP01037.1 - 3.6e-31 107.1 0.2 7.1e-31 106.2 0.2 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor DUF2722 PF10846.8 RKP01037.1 - 1.6 7.6 16.8 0.19 10.7 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Dynactin_p22 PF07426.11 RKP01038.1 - 4.2e-11 43.0 0.0 5.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Flavokinase PF01687.17 RKP01039.1 - 5e-34 116.9 0.0 5.7e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Cation_efflux PF01545.21 RKP01040.1 - 3.2e-39 134.7 4.5 5.7e-23 81.7 0.1 2.1 2 0 0 2 2 2 2 Cation efflux family MS_channel PF00924.18 RKP01040.1 - 7.9 6.0 5.8 0.47 10.0 0.4 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel Complex1_49kDa PF00346.19 RKP01041.1 - 8.4e-122 405.5 0.0 1.1e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 RKP01041.1 - 0.016 14.1 0.0 0.071 12.0 0.0 1.9 1 1 1 2 2 2 0 Nickel-dependent hydrogenase PALP PF00291.25 RKP01042.1 - 7.9e-65 219.2 0.8 1e-64 218.8 0.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 RKP01042.1 - 9.3e-14 51.6 0.0 7.8e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain His_Phos_1 PF00300.22 RKP01043.1 - 4e-25 88.6 0.5 4.3e-21 75.5 0.1 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) TPT PF03151.16 RKP01045.1 - 2e-27 96.3 14.7 2.3e-27 96.1 14.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RKP01045.1 - 7.3e-10 39.1 29.8 4e-06 27.0 7.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RKP01045.1 - 2e-06 27.3 14.7 2.4e-06 27.0 14.7 1.3 1 0 0 1 1 1 1 UAA transporter family NADHdh-2_N PF12155.8 RKP01045.1 - 0.054 13.9 0.3 0.054 13.9 0.3 2.7 2 1 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal DUF3188 PF11384.8 RKP01045.1 - 0.082 12.6 5.4 2.5 7.9 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) PUNUT PF16913.5 RKP01045.1 - 7.8 5.6 20.6 23 4.0 20.6 1.8 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Ank_2 PF12796.7 RKP01046.1 - 8e-37 125.7 11.8 1e-13 51.6 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKP01046.1 - 1.7e-20 72.8 9.9 1.2e-05 25.5 0.2 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 RKP01046.1 - 2e-19 69.6 2.7 3.3e-05 24.3 0.1 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP01046.1 - 2.9e-19 67.1 3.2 0.042 14.4 0.0 7.2 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 RKP01046.1 - 8.7e-17 60.7 8.2 0.00015 22.1 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat ACP_syn_III_C PF08541.10 RKP01046.1 - 0.047 13.9 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal fn3 PF00041.21 RKP01046.1 - 0.078 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Fibronectin type III domain DUF2369 PF10179.9 RKP01046.1 - 0.13 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Ral PF11058.8 RKP01046.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral CRIM PF16978.5 RKP01047.1 - 1.9e-41 141.5 1.3 5.8e-41 139.9 0.0 2.3 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 RKP01047.1 - 5.4e-15 55.6 0.6 2e-14 53.8 1.1 1.7 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 RKP01047.1 - 0.00026 21.0 0.1 0.00065 19.7 0.1 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 RKP01047.1 - 0.0017 18.5 0.1 0.0041 17.3 0.1 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain Cobl PF09469.10 RKP01047.1 - 0.0023 18.2 0.1 0.0047 17.2 0.1 1.4 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain p53-inducible11 PF14936.6 RKP01048.1 - 0.062 13.4 0.1 0.073 13.1 0.1 1.0 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 CGI-121 PF08617.10 RKP01050.1 - 2.6e-19 69.9 0.0 3e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 SH3_9 PF14604.6 RKP01051.1 - 8.6e-10 38.3 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01051.1 - 2.3e-06 27.1 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain TMEM154 PF15102.6 RKP01051.1 - 1.3e-05 25.1 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 RKP01051.1 - 0.061 14.2 0.0 0.13 13.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_2 PF13347.6 RKP01051.1 - 0.076 11.6 0.0 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 MFS/sugar transport protein RCR PF12273.8 RKP01051.1 - 0.12 13.1 0.0 0.31 11.7 0.0 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red K1 PF02960.14 RKP01051.1 - 0.55 10.3 4.7 0.32 11.1 0.4 2.5 2 1 0 2 2 2 0 K1 glycoprotein DUF1180 PF06679.12 RKP01051.1 - 9.5 6.6 6.1 1.1 9.6 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) SAPS PF04499.15 RKP01052.1 - 3.3e-84 283.4 0.0 9.1e-50 169.8 0.0 2.2 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Thiolase_N PF00108.23 RKP01053.1 - 2.9e-83 279.2 0.0 4e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKP01053.1 - 1.2e-32 112.2 5.5 5.3e-32 110.1 4.1 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RKP01053.1 - 3.5e-05 23.5 1.5 7.1e-05 22.5 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KH_1 PF00013.29 RKP01054.1 - 1.5e-51 172.1 9.2 2.4e-17 62.5 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RKP01054.1 - 4e-16 58.6 1.7 0.00051 19.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RKP01054.1 - 3.8e-11 42.7 0.6 0.00087 19.1 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 RKP01054.1 - 0.0027 17.7 0.0 0.59 10.2 0.0 2.9 3 0 0 3 3 3 1 KH-like RNA-binding domain SLS PF14611.6 RKP01054.1 - 0.055 13.3 0.0 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 RKP01054.1 - 0.15 12.2 4.5 7.5 6.7 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain LIM PF00412.22 RKP01055.1 - 6.3e-43 144.8 35.0 1.7e-13 50.5 4.4 4.5 4 1 0 4 4 4 4 LIM domain C2 PF00168.30 RKP01056.1 - 2.1e-18 66.5 0.0 2.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 RKP01056.1 - 0.021 14.4 0.0 0.31 10.6 0.0 2.0 1 1 1 2 2 2 0 CEP76 C2 domain DEAD PF00270.29 RKP01057.1 - 1.7e-35 122.4 0.3 3.2e-35 121.5 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01057.1 - 2.3e-25 89.1 0.2 5.3e-25 87.9 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP01057.1 - 1.3e-05 25.2 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RKP01057.1 - 0.0026 17.5 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKP01057.1 - 0.24 11.6 1.0 1.8 8.8 1.0 2.5 2 1 0 2 2 2 0 AAA domain Med8 PF10232.9 RKP01058.1 - 7.6e-07 29.0 0.0 9.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Peptidase_M75 PF09375.10 RKP01058.1 - 0.05 13.1 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Imelysin Mlh1_C PF16413.5 RKP01059.1 - 4.9e-69 232.7 0.0 7.4e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 RKP01059.1 - 2.1e-26 92.0 0.0 3.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RKP01059.1 - 4.2e-12 46.1 0.0 7.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RKP01059.1 - 2.9e-07 31.0 0.0 5.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PSK_trans_fac PF07704.11 RKP01059.1 - 0.19 12.5 0.4 0.79 10.5 0.4 2.1 1 1 0 1 1 1 0 Rv0623-like transcription factor CH_2 PF06294.11 RKP01060.1 - 3.7e-32 110.3 0.0 4.2e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RKP01060.1 - 1.1e-10 41.2 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 CAMSAP CH domain Pkinase PF00069.25 RKP01061.1 - 2.8e-64 217.0 0.0 3.2e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01061.1 - 3.6e-30 105.1 0.0 8.7e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01061.1 - 0.00024 20.5 0.0 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKP01061.1 - 0.004 16.2 0.0 0.088 11.7 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 RKP01061.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKP01061.1 - 0.042 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RKP01061.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERM PF00769.19 RKP01062.1 - 0.0014 18.5 19.1 0.0014 18.5 19.1 3.2 3 0 0 3 3 3 1 Ezrin/radixin/moesin family Cep57_MT_bd PF06657.13 RKP01062.1 - 0.0021 18.5 0.8 0.0021 18.5 0.8 6.3 5 2 2 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Adenylate_cycl PF01295.18 RKP01062.1 - 0.0076 14.9 2.1 0.019 13.6 2.1 1.6 1 0 0 1 1 1 1 Adenylate cyclase, class-I TPR_MLP1_2 PF07926.12 RKP01062.1 - 0.012 15.7 4.9 0.012 15.7 4.9 4.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 RKP01062.1 - 0.013 15.1 7.5 0.013 15.1 7.5 3.6 2 1 1 4 4 4 0 Intermediate filament protein HALZ PF02183.18 RKP01062.1 - 0.025 14.8 8.6 0.43 10.8 3.4 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper YlqD PF11068.8 RKP01062.1 - 0.029 14.8 32.0 0.13 12.7 5.1 3.9 2 1 1 3 3 3 0 YlqD protein TSC22 PF01166.18 RKP01062.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.5 3 0 0 3 3 2 0 TSC-22/dip/bun family Prefoldin_2 PF01920.20 RKP01062.1 - 0.18 11.7 0.2 0.18 11.7 0.2 5.3 4 1 2 6 6 6 0 Prefoldin subunit DUF722 PF05263.11 RKP01062.1 - 0.86 9.8 6.4 0.21 11.8 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF722) Fez1 PF06818.15 RKP01062.1 - 0.95 9.9 33.9 3.2 8.2 4.1 3.3 2 1 1 3 3 3 0 Fez1 APG6_N PF17675.1 RKP01062.1 - 2 9.0 52.2 4 8.0 13.6 4.2 2 1 1 3 3 3 0 Apg6 coiled-coil region ApoO PF09769.9 RKP01062.1 - 2.4 8.1 8.2 4.4 7.3 0.1 3.4 3 0 0 3 3 3 0 Apolipoprotein O ThrE PF06738.12 RKP01062.1 - 2.7 7.3 3.5 0.87 8.9 0.5 1.6 2 0 0 2 2 2 0 Putative threonine/serine exporter TACC_C PF05010.14 RKP01062.1 - 3.5 7.3 33.4 1.1 8.9 18.9 3.2 2 2 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 RKP01062.1 - 4 7.9 4.5 9.8 6.7 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 RKP01062.1 - 8 6.5 19.7 5.1 7.2 0.4 3.9 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 RKP01062.1 - 9.2 5.2 34.5 0.47 9.5 3.5 3.1 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_4 PF12799.7 RKP01063.1 - 1.3e-38 130.4 48.7 7.7e-06 26.2 0.1 13.6 10 4 4 15 15 15 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RKP01063.1 - 8.3e-38 129.6 16.8 1.5e-11 44.1 0.9 6.9 4 3 3 7 7 7 5 Leucine-rich repeat LRR_8 PF13855.6 RKP01063.1 - 4.9e-30 103.1 46.8 5.2e-09 35.7 5.3 9.5 6 2 5 11 11 11 9 Leucine rich repeat LRR_6 PF13516.6 RKP01063.1 - 0.01 15.8 30.1 1.2 9.4 0.0 11.2 11 1 1 12 12 12 0 Leucine Rich repeat RRM_1 PF00076.22 RKP01064.1 - 7.2e-19 67.4 0.6 8.5e-19 67.2 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKP01064.1 - 1.9e-05 24.2 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4355 PF14265.6 RKP01064.1 - 0.079 13.2 1.9 0.11 12.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RRM_Rrp7 PF17799.1 RKP01064.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain MAPEG PF01124.18 RKP01065.1 - 2.1e-10 40.6 5.4 2.6e-10 40.3 5.4 1.1 1 0 0 1 1 1 1 MAPEG family GCP_N_terminal PF17681.1 RKP01066.1 - 1.7e-44 152.7 0.0 3.1e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RKP01066.1 - 1.2e-32 113.7 0.0 2.1e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Cut8 PF08559.10 RKP01067.1 - 5.6e-19 68.7 13.7 1.1e-14 54.7 0.0 3.9 4 0 0 4 4 4 2 Cut8, nuclear proteasome tether protein Eapp_C PF10238.9 RKP01067.1 - 0.028 14.5 6.9 0.055 13.6 6.9 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein FHIPEP PF00771.20 RKP01067.1 - 0.095 11.1 1.6 0.14 10.6 1.6 1.1 1 0 0 1 1 1 0 FHIPEP family DDHD PF02862.17 RKP01067.1 - 0.64 10.1 5.8 0.23 11.6 3.2 1.5 2 0 0 2 2 2 0 DDHD domain Folliculin PF11704.8 RKP01067.1 - 1.7 8.5 5.4 3.2 7.6 5.4 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF5421 PF17458.2 RKP01067.1 - 4 6.7 9.8 6.1 6.1 9.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Spt20 PF12090.8 RKP01067.1 - 4.6 6.8 31.2 8.4 5.9 31.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 RKP01067.1 - 5.5 8.0 11.0 0.93 10.5 7.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PRP3 PF08572.10 RKP01068.1 - 2.3e-51 174.7 0.9 2.3e-51 174.7 0.9 3.2 4 0 0 4 4 4 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 RKP01068.1 - 5.8e-27 94.6 0.0 4.5e-26 91.7 0.0 2.6 2 2 0 2 2 2 1 Protein of unknown function (DUF1115) Holin_2-3 PF13272.6 RKP01068.1 - 0.075 13.3 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Putative 2/3 transmembrane domain holin Acetyltransf_1 PF00583.25 RKP01070.1 - 3.7e-09 36.8 0.0 7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKP01070.1 - 7.3e-05 23.1 0.0 0.00018 21.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKP01070.1 - 8.4e-05 22.5 0.0 0.005 16.8 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RKP01070.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 RKP01070.1 - 0.018 15.7 0.1 1.2 9.8 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RKP01070.1 - 0.091 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3439 PF11921.8 RKP01070.1 - 4.9 7.1 19.3 8.8 6.3 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_15 PF00723.21 RKP01071.1 - 3.1e-50 171.3 0.0 9e-49 166.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Sua5_yciO_yrdC PF01300.18 RKP01072.1 - 2.5e-52 177.0 0.0 2.1e-51 174.0 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 RKP01072.1 - 7.4e-23 81.6 0.0 1.2e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ribosomal_S19e PF01090.19 RKP01073.1 - 3e-53 179.2 0.1 3.3e-53 179.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_41 PF14502.6 RKP01073.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SNF2_N PF00176.23 RKP01074.1 - 1.5e-66 224.5 1.4 2.7e-66 223.7 1.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 RKP01074.1 - 2.5e-42 144.4 14.5 7.9e-42 142.8 14.5 1.9 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 RKP01074.1 - 2e-17 63.5 0.0 4.8e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP01074.1 - 1e-07 32.1 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RKP01074.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TFIIA PF03153.13 RKP01075.1 - 0.32 10.9 17.6 0.36 10.8 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PTPlike_phytase PF14566.6 RKP01076.1 - 1.5e-128 424.8 0.0 9.8e-47 159.0 0.1 3.3 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 RKP01076.1 - 0.00019 21.1 0.0 0.78 9.3 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 RKP01076.1 - 0.044 13.6 0.0 17 5.3 0.0 3.3 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 RKP01076.1 - 0.068 13.1 0.0 5.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Tyrosine phosphatase family MCM PF00493.23 RKP01077.1 - 1e-99 332.2 0.0 1.5e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RKP01077.1 - 6e-36 123.1 1.0 1.2e-35 122.1 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKP01077.1 - 1e-26 93.1 0.2 2.1e-26 92.2 0.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RKP01077.1 - 2.1e-12 47.5 0.0 6.8e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 RKP01077.1 - 2.4e-08 34.1 0.0 6.9e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RKP01077.1 - 3.2e-07 29.9 0.2 0.00035 20.0 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RKP01077.1 - 0.00048 20.0 0.0 0.0017 18.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP01077.1 - 0.00083 19.8 0.2 0.015 15.7 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 RKP01077.1 - 0.0044 16.7 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain NTPase_1 PF03266.15 RKP01077.1 - 0.13 12.2 0.2 18 5.2 0.1 2.7 2 1 1 3 3 3 0 NTPase CH_2 PF06294.11 RKP01078.1 - 8.8e-07 29.0 0.0 2.6e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 RKP01078.1 - 0.00015 21.9 0.7 0.17 12.0 0.0 3.4 3 0 0 3 3 3 2 Adenylate kinase DUF4096 PF13340.6 RKP01078.1 - 0.075 13.3 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) PHD PF00628.29 RKP01079.1 - 1.7e-05 24.6 0.7 1.7e-05 24.6 0.7 3.6 3 0 0 3 3 3 1 PHD-finger zf-UBR PF02207.20 RKP01079.1 - 6.9e-05 22.9 14.8 6.9e-05 22.9 14.8 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) C1_1 PF00130.22 RKP01079.1 - 0.038 13.9 14.0 1 9.3 3.9 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Coa1 PF08695.10 RKP01080.1 - 2.1e-09 37.2 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 V-ATPase_H_N PF03224.14 RKP01081.1 - 7.7e-66 222.5 0.1 9.3e-66 222.3 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 RKP01081.1 - 2.8e-36 124.2 0.0 2.8e-35 121.0 0.0 2.4 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 RKP01081.1 - 0.00038 20.4 5.1 3.8 7.7 0.0 5.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKP01081.1 - 0.00093 19.5 0.2 0.65 10.4 0.0 3.8 2 2 2 4 4 4 1 HEAT repeats HEAT PF02985.22 RKP01081.1 - 0.057 13.7 0.0 2.7 8.5 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 RKP01081.1 - 0.11 13.1 1.1 25 5.5 0.0 4.3 5 1 0 5 5 5 0 HEAT-like repeat Metallophos PF00149.28 RKP01082.1 - 0.00022 21.8 0.0 0.00053 20.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STAG PF08514.11 RKP01082.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 STAG domain Vac14_Fig4_bd PF11916.8 RKP01083.1 - 1.2e-74 249.8 5.0 1.2e-74 249.8 5.0 2.5 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 RKP01083.1 - 4.4e-38 129.8 0.0 6.3e-36 122.9 0.0 3.7 3 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 RKP01083.1 - 2.3e-12 46.1 0.1 0.00089 19.3 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 RKP01083.1 - 2.5e-11 43.8 2.1 0.0057 17.0 0.0 5.7 4 3 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 RKP01083.1 - 3.4e-05 24.2 0.1 0.029 14.9 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 RKP01083.1 - 3.6e-05 23.5 1.5 12 5.4 0.0 4.8 4 1 1 5 5 5 2 CLASP N terminal Adaptin_N PF01602.20 RKP01083.1 - 7.4e-05 21.5 4.7 0.1 11.2 0.0 3.6 2 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 RKP01083.1 - 0.00011 22.3 3.9 1.5 8.8 0.0 4.4 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 RKP01083.1 - 0.0013 18.8 4.5 0.026 14.7 0.0 4.0 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF5071 PF16804.5 RKP01083.1 - 0.044 14.0 0.7 13 6.1 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5071) RasGEF_N_2 PF14663.6 RKP01083.1 - 0.086 13.2 5.1 2.4 8.6 0.3 4.3 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2722 PF10846.8 RKP01084.1 - 0.0032 16.5 11.3 0.0032 16.5 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 RKP01084.1 - 0.088 12.8 15.4 0.087 12.8 15.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 RKP01084.1 - 0.09 13.2 5.4 0.12 12.8 5.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 RKP01084.1 - 0.11 12.1 21.3 0.13 11.8 21.3 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 RKP01084.1 - 0.22 12.2 14.5 0.25 12.0 14.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 RKP01084.1 - 0.27 10.0 3.0 0.26 10.0 3.0 1.0 1 0 0 1 1 1 0 Presenilin Opi1 PF08618.10 RKP01084.1 - 0.3 10.3 4.8 0.34 10.1 4.8 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DUF4834 PF16118.5 RKP01084.1 - 0.4 11.7 5.9 0.5 11.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 RKP01084.1 - 0.67 8.9 6.5 0.63 9.0 6.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FTZ PF03867.14 RKP01084.1 - 0.75 9.3 7.3 0.9 9.0 7.3 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Suf PF05843.14 RKP01084.1 - 1 9.3 6.6 1.1 9.2 6.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 RKP01084.1 - 1.6 7.8 8.0 1.8 7.6 8.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein UPF0560 PF10577.9 RKP01084.1 - 3.9 5.9 10.1 4.3 5.7 10.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ArfGap PF01412.18 RKP01085.1 - 4.1e-28 97.8 1.0 4.4e-28 97.7 1.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GATA PF00320.27 RKP01085.1 - 0.062 12.9 0.5 0.091 12.4 0.5 1.3 1 0 0 1 1 1 0 GATA zinc finger Sld5 PF05916.11 RKP01087.1 - 3.9e-14 53.0 0.0 5.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein NUC153 PF08159.12 RKP01088.1 - 6.4e-12 45.1 9.1 1.2e-11 44.2 1.0 3.7 3 0 0 3 3 3 1 NUC153 domain AF-4 PF05110.13 RKP01088.1 - 2.3e-05 22.8 22.5 2.3e-05 22.8 22.5 3.2 3 0 0 3 3 3 1 AF-4 proto-oncoprotein DDHD PF02862.17 RKP01088.1 - 0.094 12.9 9.1 0.041 14.1 2.3 2.4 2 0 0 2 2 2 0 DDHD domain DUF515 PF04415.12 RKP01088.1 - 0.25 9.7 7.2 0.43 8.9 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Trypan_PARP PF05887.11 RKP01088.1 - 0.47 10.4 16.4 0.033 14.2 9.8 2.4 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 RKP01088.1 - 0.54 10.0 23.0 1.1 9.0 4.7 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TMEM51 PF15345.6 RKP01088.1 - 2.5 7.9 9.2 0.2 11.5 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 51 Presenilin PF01080.17 RKP01088.1 - 2.9 6.6 14.6 0.29 9.9 5.9 2.2 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 RKP01088.1 - 6.1 6.0 8.2 0.57 9.3 3.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Raftlin PF15250.6 RKP01088.1 - 6.5 5.4 13.6 0.45 9.2 6.6 2.1 2 0 0 2 2 2 0 Raftlin CAP_GLY PF01302.25 RKP01089.1 - 1.4e-25 89.1 0.1 4.6e-25 87.4 0.1 1.9 2 0 0 2 2 2 1 CAP-Gly domain Ubiquitin_2 PF14560.6 RKP01089.1 - 1.3e-22 80.0 0.0 2.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 RKP01089.1 - 0.02 14.6 0.0 0.046 13.5 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family T6_Ig_like PF18002.1 RKP01089.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 T6 antigen Ig like domain PAP_central PF04928.17 RKP01090.1 - 7.9e-96 319.8 0.0 1e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 RKP01090.1 - 2e-29 102.4 0.0 9.9e-29 100.1 0.0 1.9 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 RKP01090.1 - 2.4e-08 34.2 0.0 5.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 RKP01090.1 - 7.7e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain bZIP_1 PF00170.21 RKP01091.1 - 2.3e-05 24.4 26.5 3.2e-05 23.9 12.2 4.4 4 0 0 4 4 4 2 bZIP transcription factor bZIP_2 PF07716.15 RKP01091.1 - 8.2e-05 22.6 14.2 8.2e-05 22.6 14.2 7.2 9 0 0 9 9 9 2 Basic region leucine zipper Shugoshin_N PF07558.11 RKP01091.1 - 0.012 15.5 0.9 0.35 10.8 0.7 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 RKP01091.1 - 0.069 13.5 0.2 0.069 13.5 0.2 4.3 5 0 0 5 5 5 0 TSC-22/dip/bun family CH PF00307.31 RKP01092.1 - 2.7e-06 27.5 0.0 5.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain UreE_C PF05194.12 RKP01092.1 - 2.7 8.6 10.3 14 6.2 10.3 2.2 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain YEATS PF03366.16 RKP01093.1 - 4.7e-07 29.7 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 YEATS family Ribosomal_L4 PF00573.22 RKP01094.1 - 3.9e-40 137.6 1.6 3.9e-40 137.6 1.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 RKP01094.1 - 7.4e-23 80.4 0.7 3.3e-20 71.9 0.5 2.6 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Dzip-like_N PF13815.6 RKP01094.1 - 0.11 12.4 0.4 0.31 11.0 0.1 1.8 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal PWI PF01480.17 RKP01095.1 - 0.00023 21.4 0.0 0.00042 20.6 0.0 1.3 1 0 0 1 1 1 1 PWI domain Orbi_NS3 PF01616.16 RKP01095.1 - 0.46 10.2 1.9 1.1 8.9 1.9 1.6 1 0 0 1 1 1 0 Orbivirus NS3 DUF444 PF04285.12 RKP01095.1 - 0.98 8.4 3.7 1.7 7.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Pkinase PF00069.25 RKP01096.1 - 3.8e-70 236.3 0.0 4.3e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01096.1 - 9.9e-43 146.3 0.0 1.2e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01096.1 - 7.3e-07 28.8 0.0 6e-06 25.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 RKP01096.1 - 0.01 15.4 0.2 0.23 11.0 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RKP01096.1 - 0.039 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 RKP01096.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_binding_8 PF13450.6 RKP01097.1 - 1.6e-06 28.2 0.1 5.5e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RKP01097.1 - 2.6e-06 27.1 0.0 2.6e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RKP01097.1 - 0.00023 20.0 0.3 0.00032 19.5 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 RKP01097.1 - 0.00083 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 RKP01097.1 - 0.0072 14.8 0.0 0.0097 14.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like GIDA PF01134.22 RKP01097.1 - 0.0077 15.4 0.4 0.011 14.8 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 RKP01097.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RKP01097.1 - 0.072 12.4 1.5 0.18 11.1 1.5 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 RKP01097.1 - 0.074 13.6 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 RKP01097.1 - 0.93 9.4 5.6 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RGS PF00615.19 RKP01099.1 - 1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 RKP01099.1 - 4.7e-09 36.2 0.0 1.3e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS_DHEX PF18148.1 RKP01099.1 - 0.0012 18.9 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain DnaJ-X PF14308.6 RKP01100.1 - 5.1e-42 143.7 0.0 6.1e-41 140.2 0.0 2.1 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 RKP01100.1 - 4.7e-24 84.3 0.7 8.4e-24 83.5 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain LIM PF00412.22 RKP01100.1 - 0.2 11.9 0.3 0.42 10.9 0.3 1.5 1 0 0 1 1 1 0 LIM domain SH3_9 PF14604.6 RKP01101.1 - 2.3e-10 40.2 0.0 1.5e-09 37.6 0.0 2.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01101.1 - 8.1e-08 31.8 0.1 3.2e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 SH3 domain GRP PF07172.11 RKP01101.1 - 0.0022 18.7 12.6 0.0022 18.7 12.6 5.6 5 1 1 6 6 6 2 Glycine rich protein family TMEM52 PF14979.6 RKP01101.1 - 0.053 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Transmembrane 52 RCR PF12273.8 RKP01101.1 - 0.076 13.7 4.8 0.085 13.5 0.0 3.6 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red SH3_2 PF07653.17 RKP01101.1 - 0.096 12.4 0.0 0.4 10.4 0.0 2.2 1 0 0 1 1 1 0 Variant SH3 domain Sec7 PF01369.20 RKP01102.1 - 4.4e-70 235.1 0.4 7.2e-70 234.4 0.4 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 RKP01102.1 - 2.8e-37 128.1 1.2 4.3e-36 124.2 0.0 3.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 RKP01102.1 - 1.3e-19 70.5 0.0 1.4e-18 67.2 0.0 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 RKP01102.1 - 1.6e-17 63.1 0.1 4.8e-10 39.1 0.0 5.2 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) Cwf_Cwc_15 PF04889.12 RKP01102.1 - 0.7 9.6 3.2 1.5 8.5 3.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HisG PF01634.18 RKP01103.1 - 1.9e-46 158.0 0.0 2.7e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 RKP01103.1 - 1.1e-27 96.0 0.1 1.9e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain DUF3995 PF13160.6 RKP01103.1 - 3.6 8.0 8.0 0.066 13.6 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Chitin_synth_1 PF01644.17 RKP01104.1 - 1.5e-72 242.9 0.2 2.2e-72 242.4 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 RKP01104.1 - 3.2e-25 87.9 0.0 1.2e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 RKP01104.1 - 4.7e-24 84.9 5.0 4e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RKP01104.1 - 7e-06 26.1 9.1 7e-06 26.1 9.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 LRR19-TM PF15176.6 RKP01104.1 - 0.14 12.2 2.0 0.32 11.0 1.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Aminotran_5 PF00266.19 RKP01105.1 - 4.2e-91 305.7 0.0 4.9e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 RKP01105.1 - 2.2e-07 30.5 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 RKP01105.1 - 4.9e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 RKP01105.1 - 0.00031 19.6 0.0 0.00048 18.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 RKP01105.1 - 0.00054 19.4 0.7 0.00088 18.7 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GTP_cyclohydro2 PF00925.20 RKP01106.1 - 1.4e-49 167.8 0.3 5.1e-48 162.7 0.3 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Coiled-coil_56 PF09813.9 RKP01107.1 - 1.3e-05 25.1 0.1 2.3e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 Arrestin_C PF02752.22 RKP01108.1 - 0.0002 21.8 0.0 0.00036 21.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RKP01108.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GIT_CC PF16559.5 RKP01108.1 - 0.09 12.7 5.9 0.46 10.4 0.1 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 RKP01108.1 - 5 7.3 6.8 2.1 8.5 2.9 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 MIS13 PF08202.11 RKP01109.1 - 1.9e-27 96.4 0.0 3.3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Evr1_Alr PF04777.13 RKP01110.1 - 8.9e-28 96.7 0.0 1e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Ribosomal_L7Ae PF01248.26 RKP01111.1 - 2.1e-23 81.9 1.9 2.7e-23 81.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RLAN PF14401.6 RKP01111.1 - 0.057 13.1 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain ATP-grasp_6 PF18419.1 RKP01111.1 - 0.088 12.5 0.0 0.36 10.5 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp-like domain UBA PF00627.31 RKP01112.1 - 6.7e-07 29.1 0.3 6.7e-07 29.1 0.3 2.6 3 0 0 3 3 3 1 UBA/TS-N domain STI1 PF17830.1 RKP01112.1 - 2e-06 27.7 7.3 0.0002 21.2 2.2 2.4 1 1 1 2 2 2 2 STI1 domain ubiquitin PF00240.23 RKP01112.1 - 0.0012 18.6 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Avl9 PF09794.9 RKP01113.1 - 1.8e-39 135.5 0.0 2.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.12 RKP01113.1 - 0.0079 16.7 0.0 0.022 15.3 0.0 1.7 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 RKP01113.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Catalase PF00199.19 RKP01114.1 - 1.1e-129 433.0 0.0 1.3e-129 432.7 0.0 1.0 1 0 0 1 1 1 1 Catalase DLIC PF05783.11 RKP01116.1 - 4.9e-48 164.1 12.4 2.3e-42 145.4 0.0 3.7 1 1 2 3 3 3 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 RKP01116.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RKP01116.1 - 2.4 8.5 5.3 2.4 8.5 0.8 3.0 3 1 0 3 3 3 0 AAA ATPase domain URO-D PF01208.17 RKP01117.1 - 6.5e-129 430.0 0.0 7.3e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DNApol_Exo PF18136.1 RKP01118.1 - 1.4e-88 296.7 0.0 2.5e-88 295.9 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 RKP01118.1 - 1.4e-41 142.8 0.0 2.1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DUF3678 PF12435.8 RKP01118.1 - 2.6 7.5 6.7 2.2 7.7 4.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF2749 PF10907.8 RKP01119.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) DSPc PF00782.20 RKP01120.1 - 1.4e-24 86.4 0.0 1.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKP01120.1 - 0.0001 22.0 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.13 RKP01120.1 - 0.00057 19.9 0.1 0.00057 19.9 0.1 1.5 2 0 0 2 2 2 1 Putative phosphatase (DUF442) PTPlike_phytase PF14566.6 RKP01120.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate PAXNEB PF05625.11 RKP01121.1 - 1.8e-28 99.8 0.0 3.3e-23 82.4 0.0 2.3 2 0 0 2 2 2 2 PAXNEB protein ATPase PF06745.13 RKP01121.1 - 0.31 10.3 0.0 0.44 9.9 0.0 1.2 1 0 0 1 1 1 0 KaiC DHBP_synthase PF00926.19 RKP01122.1 - 1.2e-72 243.5 0.5 1.6e-72 243.1 0.5 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-C2H2 PF00096.26 RKP01123.1 - 6e-06 26.4 7.4 0.022 15.2 1.0 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP01123.1 - 0.015 16.1 1.0 0.015 16.1 1.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RKP01123.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.8 3 0 0 3 3 3 0 Aberrant zinc-finger Collagen PF01391.18 RKP01123.1 - 4.5 7.1 16.7 3.9 7.3 4.5 3.5 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) API5 PF05918.11 RKP01124.1 - 1 8.1 4.6 1 8.1 4.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cpn60_TCP1 PF00118.24 RKP01125.1 - 1.7e-150 501.9 3.2 1.9e-150 501.8 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2070 PF09843.9 RKP01128.1 - 2.8 6.1 8.5 3.5 5.8 8.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3099 PF11298.8 RKP01128.1 - 7.6 6.8 13.6 4.9 7.4 4.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3099) DEAD PF00270.29 RKP01130.1 - 3.9e-37 127.7 0.0 6.5e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01130.1 - 5.6e-18 65.3 0.0 2.1e-17 63.5 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RKP01130.1 - 6e-17 61.6 0.0 2e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) zf-C3HC4_4 PF15227.6 RKP01132.1 - 1.7e-06 28.1 6.8 3.5e-06 27.1 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RKP01132.1 - 0.00028 20.8 8.2 0.00028 20.8 8.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RKP01132.1 - 0.0012 18.6 7.4 0.0042 16.9 7.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP01132.1 - 0.0018 18.2 7.3 0.0048 16.8 7.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RKP01132.1 - 0.0044 16.8 3.7 0.012 15.4 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP01132.1 - 0.0055 16.6 8.4 0.0055 16.6 8.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKP01132.1 - 0.034 14.0 4.1 0.077 12.9 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RKP01132.1 - 0.1 13.0 7.0 0.29 11.5 7.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 RKP01132.1 - 0.24 11.2 2.7 0.62 9.9 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 RKP01132.1 - 0.27 11.1 1.1 0.55 10.1 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein OrfB_Zn_ribbon PF07282.11 RKP01132.1 - 0.36 10.8 3.6 2.7 8.0 1.4 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-MIZ PF02891.20 RKP01132.1 - 3.2 7.6 8.4 1.4 8.7 5.4 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Spt4 PF06093.13 RKP01132.1 - 7.9 6.7 10.8 0.29 11.3 2.9 2.6 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger Pro_isomerase PF00160.21 RKP01133.1 - 3.5e-44 150.9 0.0 3.9e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.21 RKP01134.1 - 3.5e-240 798.8 0.0 4.3e-240 798.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RKP01134.1 - 2.9e-44 151.0 0.7 4.9e-44 150.3 0.7 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 RKP01134.1 - 5.8e-18 64.5 0.4 1.2e-17 63.4 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01134.1 - 2e-15 56.1 0.0 4.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKP01134.1 - 1.7e-11 43.6 0.0 4.8e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 RKP01134.1 - 0.011 16.0 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RKP01134.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 RKP01134.1 - 0.087 12.1 0.0 0.087 12.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin IQ PF00612.27 RKP01134.1 - 0.14 12.0 1.0 0.38 10.7 1.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif RNase_PH PF01138.21 RKP01135.1 - 2.4e-14 54.0 0.1 2.4e-14 54.0 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RKP01135.1 - 1.7e-08 34.4 0.0 3.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3418 PF11898.8 RKP01135.1 - 0.12 11.1 0.5 0.18 10.4 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3418) UCR_UQCRX_QCR9 PF05365.12 RKP01136.1 - 1.9e-20 72.6 1.2 1.9e-20 72.6 1.2 1.4 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DNA_primase_S PF01896.19 RKP01137.1 - 2e-42 145.2 0.0 2.8e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit Spc7 PF08317.11 RKP01140.1 - 0.0042 16.0 12.6 0.0042 16.0 12.6 5.1 1 1 4 5 5 5 4 Spc7 kinetochore protein HMMR_N PF15905.5 RKP01140.1 - 0.005 16.4 22.3 0.005 16.4 22.3 5.6 2 1 4 6 6 6 2 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 RKP01140.1 - 0.0051 16.8 0.7 0.0051 16.8 0.7 8.8 6 3 3 11 11 11 4 TATA element modulatory factor 1 DNA binding DUF515 PF04415.12 RKP01141.1 - 0.0061 15.0 6.1 0.023 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF515) TMEM154 PF15102.6 RKP01141.1 - 0.075 12.9 11.8 4 7.3 11.8 2.2 1 1 0 1 1 1 0 TMEM154 protein family Plasmodium_Vir PF05795.11 RKP01141.1 - 0.35 10.2 1.4 0.49 9.8 1.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 RKP01141.1 - 0.88 9.4 8.2 1.1 9.1 8.2 1.1 1 0 0 1 1 1 0 SPX domain Mid2 PF04478.12 RKP01141.1 - 9.3 6.1 9.6 0.26 11.1 0.5 2.6 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor Glyco_hydro_77 PF02446.17 RKP01142.1 - 1.7e-150 501.9 0.0 2.4e-150 501.5 0.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase SH3_9 PF14604.6 RKP01143.1 - 1.3e-09 37.7 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01143.1 - 3.3e-09 36.2 0.0 5.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Orf78 PF06024.12 RKP01143.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) FeoB_associated PF12669.7 RKP01143.1 - 0.02 15.3 2.4 0.02 15.3 2.4 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein RCR PF12273.8 RKP01143.1 - 0.036 14.7 0.1 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1180 PF06679.12 RKP01143.1 - 0.051 14.0 0.1 0.051 14.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ODV-E18 PF10717.9 RKP01143.1 - 0.073 12.9 0.3 0.21 11.5 0.3 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 RKP01143.1 - 0.12 13.3 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 RKP01143.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4577 PF15145.6 RKP01143.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Gti1_Pac2 PF09729.9 RKP01144.1 - 3.7e-42 144.5 0.8 1.3e-35 123.2 0.1 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family PPV_E2_C PF00511.17 RKP01144.1 - 0.067 13.4 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 E2 (early) protein, C terminal Arrestin_C PF02752.22 RKP01145.1 - 0.00037 20.9 0.0 0.0058 17.1 0.0 2.7 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RKP01145.1 - 0.06 13.4 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain IFRD PF05004.13 RKP01146.1 - 0.078 12.1 0.1 9.3 5.3 0.0 3.2 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 RKP01146.1 - 0.95 9.9 8.9 1 9.8 0.3 4.4 4 0 0 4 4 4 0 HEAT repeat Fcf1 PF04900.12 RKP01147.1 - 1.5e-26 92.6 0.1 2.1e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 RKP01147.1 - 2.8e-05 24.4 0.1 7.8e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 PIN like domain POR_N PF01855.19 RKP01147.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg EXOSC1 PF10447.9 RKP01148.1 - 1.6e-15 57.7 0.9 3.2e-10 40.6 0.0 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 RKP01148.1 - 1.1e-11 44.3 0.1 2.5e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region HlyIII PF03006.20 RKP01149.1 - 3.3e-47 161.1 26.9 4.9e-47 160.5 26.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related QRPTase_C PF01729.19 RKP01150.1 - 5e-48 163.1 0.0 9e-48 162.2 0.0 1.4 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 RKP01150.1 - 2.1e-16 59.8 0.0 7.2e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRKCSH-like PF12999.7 RKP01151.1 - 5.7e-31 107.7 0.9 6.3e-29 101.0 0.9 2.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 RKP01151.1 - 2.1e-13 50.3 0.0 4.7e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 RKP01151.1 - 0.0055 17.7 0.0 0.011 16.7 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4637 PF15470.6 RKP01151.1 - 0.028 14.2 0.8 0.092 12.5 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ldl_recept_a PF00057.18 RKP01151.1 - 0.97 9.7 10.9 0.37 11.0 1.0 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF4611 PF15387.6 RKP01151.1 - 1.1 9.6 6.3 0.87 9.8 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TFIIA PF03153.13 RKP01151.1 - 3.9 7.4 12.4 0.69 9.8 4.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRR_8 PF13855.6 RKP01152.1 - 3.3e-16 58.8 16.6 6.2e-09 35.5 0.3 4.7 4 1 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 RKP01152.1 - 2.8e-15 56.2 4.0 7.6e-06 26.2 0.1 5.3 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP01152.1 - 3.1e-06 26.9 5.3 18 6.4 0.1 7.1 8 0 0 8 8 8 2 Leucine Rich Repeat Filamin PF00630.19 RKP01152.1 - 0.00071 20.4 0.0 0.0013 19.5 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat UCH PF00443.29 RKP01153.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF1180 PF06679.12 RKP01153.1 - 0.51 10.7 3.0 0.83 10.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Chitin_synth_2 PF03142.15 RKP01154.1 - 2.4e-216 719.5 0.1 3.6e-216 718.9 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 RKP01154.1 - 6.6e-91 305.5 0.0 9.6e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.6 RKP01154.1 - 1.8e-12 47.6 0.0 5.2e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DEK_C PF08766.11 RKP01154.1 - 1.2e-11 44.4 0.0 7.5e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 RKP01154.1 - 3.2e-10 40.3 1.2 3.2e-10 40.3 1.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 RKP01154.1 - 0.00045 20.1 0.0 0.0028 17.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RKP01154.1 - 0.052 13.0 0.0 0.32 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 TIM PF00121.18 RKP01154.1 - 0.068 12.5 0.1 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Triosephosphate isomerase Mg_chelatase PF01078.21 RKP01154.1 - 0.14 11.5 0.3 0.32 10.4 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RKP01154.1 - 0.15 12.0 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RKP01154.1 - 0.18 11.5 0.6 0.38 10.4 0.6 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 RKP01154.1 - 2.5 8.5 4.9 3.8 7.9 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain Myosin_head PF00063.21 RKP01155.1 - 6.9e-26 90.7 0.0 1.7e-24 86.1 0.0 2.6 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 RKP01155.1 - 5.3e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain AAA_16 PF13191.6 RKP01155.1 - 0.0028 18.1 0.1 0.01 16.3 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain BUD22 PF09073.10 RKP01156.1 - 2.3 7.5 9.6 4.9 6.4 9.6 1.6 1 0 0 1 1 1 0 BUD22 ZapB PF06005.12 RKP01157.1 - 2.5 8.6 7.7 0.095 13.2 0.4 2.3 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 RKP01157.1 - 3.3 8.1 12.7 0.55 10.7 0.6 2.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Fez1 PF06818.15 RKP01157.1 - 7.9 6.9 8.6 8.4 6.8 0.3 2.5 2 0 0 2 2 2 0 Fez1 Ras PF00071.22 RKP01158.1 - 1.3e-50 171.2 0.0 1.5e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP01158.1 - 1.2e-18 67.5 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP01158.1 - 2.5e-06 27.1 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Macoilin PF09726.9 RKP01160.1 - 7.1 5.0 11.1 0.36 9.3 5.0 1.8 2 0 0 2 2 2 0 Macoilin family DnaJ PF00226.31 RKP01162.1 - 1.9e-20 72.8 1.2 4.8e-20 71.4 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 RKP01162.1 - 5.2e-20 70.4 13.9 7.4e-07 28.7 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 RKP01162.1 - 1.8e-19 68.2 25.1 1.2e-05 25.1 0.1 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01162.1 - 5e-13 49.1 24.6 0.00011 22.4 0.1 7.0 6 3 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKP01162.1 - 3.8e-10 40.1 17.8 0.056 14.0 0.8 6.2 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKP01162.1 - 4e-10 39.1 4.4 0.012 15.7 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP01162.1 - 1.5e-09 37.2 14.0 0.00062 19.6 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKP01162.1 - 1e-08 34.7 20.3 3e-06 26.8 0.1 6.7 7 0 0 7 7 6 2 TPR repeat TPR_16 PF13432.6 RKP01162.1 - 2.4e-06 28.1 1.8 0.00041 20.9 0.4 8.0 7 3 2 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 RKP01162.1 - 0.00014 22.0 14.5 0.34 11.4 0.1 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKP01162.1 - 0.0026 18.3 19.7 1.3 9.8 0.1 7.6 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF4129 PF13559.6 RKP01162.1 - 0.0068 16.6 2.3 0.0068 16.6 2.3 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) TPR_14 PF13428.6 RKP01162.1 - 0.0074 17.0 0.2 0.0074 17.0 0.2 8.7 7 2 3 10 10 8 2 Tetratricopeptide repeat DUF5113 PF17140.4 RKP01162.1 - 0.0076 16.1 2.3 0.11 12.3 0.9 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5113) TPR_9 PF13371.6 RKP01162.1 - 0.023 14.8 20.4 2.3 8.4 0.3 6.7 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP01162.1 - 0.024 14.5 14.8 0.68 9.9 0.2 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RKP01162.1 - 0.08 13.4 10.3 0.53 10.7 0.0 4.4 4 2 1 6 6 5 0 Alkyl sulfatase dimerisation HEAT_2 PF13646.6 RKP01162.1 - 0.084 13.3 4.2 0.27 11.6 1.8 2.9 2 0 0 2 2 2 0 HEAT repeats TPR_3 PF07720.12 RKP01162.1 - 0.13 12.3 9.0 2.1 8.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKP01162.1 - 0.14 12.3 13.9 2 8.6 0.0 6.1 6 2 2 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 RKP01162.1 - 0.26 11.4 9.1 1.2 9.2 0.4 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 RKP01162.1 - 0.38 11.0 21.6 1.5 9.1 0.0 6.6 7 1 1 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 RKP01162.1 - 6.8 7.6 17.3 1.6 9.6 0.1 6.2 6 0 0 6 6 4 0 Tetratricopeptide repeat Not3 PF04065.15 RKP01163.1 - 1.4e-89 299.6 20.5 1.8e-89 299.2 20.5 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 RKP01163.1 - 7.4e-38 129.6 1.4 7.4e-38 129.6 1.4 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 RKP01163.1 - 0.12 12.7 3.9 0.12 12.8 0.9 2.2 2 0 0 2 2 2 0 Syntaxin-like protein Sin3_corepress PF08295.12 RKP01163.1 - 2.1 8.5 5.7 34 4.6 0.0 3.5 3 1 1 4 4 4 0 Sin3 family co-repressor MMR_HSR1 PF01926.23 RKP01164.1 - 6.7e-10 39.1 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP01164.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RKP01164.1 - 0.041 13.8 0.0 0.21 11.5 0.0 2.1 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 RKP01164.1 - 0.15 12.1 0.3 2.6 8.1 0.3 2.1 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 RKP01164.1 - 0.2 11.9 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase tRNA_anti-codon PF01336.25 RKP01165.1 - 0.00032 20.6 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain POT1 PF02765.17 RKP01165.1 - 0.0036 17.2 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 TubC_N PF18563.1 RKP01165.1 - 0.14 12.2 0.1 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 TubC N-terminal docking domain Methyltr_RsmB-F PF01189.17 RKP01166.1 - 5.6e-31 107.8 0.0 8.3e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RKP01166.1 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 RKP01166.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin YCII PF03795.14 RKP01167.1 - 2.4e-12 47.1 0.0 3.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Thr_synth_N PF14821.6 RKP01168.1 - 3.1e-27 94.6 0.0 9.1e-27 93.1 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 RKP01168.1 - 3.9e-15 56.1 0.1 2e-14 53.7 0.1 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CDT1 PF08839.11 RKP01169.1 - 4.1e-20 72.8 0.0 7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 RKP01169.1 - 7.2e-12 45.6 0.2 2.3e-11 44.0 0.2 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain 4HBT_2 PF13279.6 RKP01170.1 - 2.1e-06 28.2 0.0 3.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 RKP01170.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Na_H_Exchanger PF00999.21 RKP01171.1 - 3.2e-71 240.1 33.6 3.7e-71 239.9 33.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF667 PF05018.13 RKP01172.1 - 1.6e-92 308.4 0.4 1.7e-92 308.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) TPR_2 PF07719.17 RKP01173.1 - 2.9e-13 48.8 12.3 0.019 15.0 0.2 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKP01173.1 - 1e-06 29.1 13.4 0.0056 17.2 0.1 6.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 RKP01173.1 - 2.6e-06 27.0 17.9 0.14 12.1 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01173.1 - 8.1e-06 26.0 9.5 4.2 7.7 0.0 7.6 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 RKP01173.1 - 0.00077 20.1 1.9 9.8 6.9 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP01173.1 - 0.0011 19.2 23.3 0.94 9.8 0.3 6.1 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RKP01173.1 - 0.002 18.0 3.2 1.7 8.9 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKP01173.1 - 0.0082 16.3 14.2 3.3 8.1 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKP01173.1 - 0.0086 16.7 0.0 0.11 13.2 0.0 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKP01173.1 - 0.015 16.0 9.7 2.2 9.3 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF1266 PF06889.11 RKP01173.1 - 0.017 15.2 0.4 0.051 13.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) TPR_15 PF13429.6 RKP01173.1 - 0.065 12.4 6.8 3.9 6.6 0.8 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 RKP01173.1 - 0.27 11.3 0.1 0.27 11.3 0.1 4.7 4 1 0 5 5 5 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 RKP01173.1 - 0.31 11.2 8.5 1.6 8.8 0.1 3.3 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat RCC1 PF00415.18 RKP01174.1 - 3.8e-24 85.1 1.1 2.7e-07 31.1 0.2 5.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKP01174.1 - 1.4e-12 47.1 15.8 4.6e-06 26.3 0.2 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 RKP01174.1 - 0.00018 21.7 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ank_3 PF13606.6 RKP01174.1 - 0.01 16.3 0.0 32 5.6 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 RKP01174.1 - 0.017 15.7 0.1 0.067 13.8 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKP01174.1 - 0.019 15.3 4.4 0.3 11.5 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 RKP01174.1 - 0.16 12.6 0.2 1.6 9.4 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) FOXP-CC PF16159.5 RKP01175.1 - 0.031 14.9 6.5 1.3 9.7 0.0 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RKP01175.1 - 0.054 13.6 1.9 6.9 6.8 0.2 2.5 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 RKP01175.1 - 0.094 13.6 17.9 1.1 10.3 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_12 PF18658.1 RKP01175.1 - 0.13 11.8 3.9 1.2 8.7 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-BED PF02892.15 RKP01175.1 - 0.25 11.4 5.1 7.2 6.7 0.8 2.6 2 0 0 2 2 2 0 BED zinc finger Metallophos PF00149.28 RKP01176.1 - 6.9e-36 124.7 0.6 1.1e-35 124.0 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKP01176.1 - 0.0006 20.2 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 RKP01177.1 - 5.1e-21 74.6 6.5 5.1e-06 27.1 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01177.1 - 1.6e-06 28.3 0.0 0.37 11.1 0.0 4.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cep57_CLD_2 PF14197.6 RKP01177.1 - 0.00079 19.5 8.5 0.018 15.1 2.9 2.4 1 1 0 2 2 2 2 Centrosome localisation domain of PPC89 Ge1_WD40 PF16529.5 RKP01177.1 - 0.0085 15.1 0.0 2.3 7.1 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CENP-F_leu_zip PF10473.9 RKP01177.1 - 0.028 14.4 5.2 0.049 13.7 5.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 RKP01177.1 - 0.31 10.6 4.3 0.54 9.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6_N PF17675.1 RKP01177.1 - 0.57 10.7 5.1 1.3 9.5 5.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region PQQ_3 PF13570.6 RKP01177.1 - 0.7 10.5 10.1 2.7 8.6 0.7 4.0 3 0 0 3 3 3 0 PQQ-like domain Ntox15 PF15604.6 RKP01177.1 - 0.83 9.8 4.6 1.7 8.8 4.6 1.4 1 0 0 1 1 1 0 Novel toxin 15 Fez1 PF06818.15 RKP01177.1 - 6.8 7.1 8.5 8.7 6.7 7.7 1.4 1 1 0 1 1 1 0 Fez1 DivIC PF04977.15 RKP01177.1 - 8.1 6.3 7.6 5.5 6.8 3.4 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 RKP01178.1 - 0.0084 16.6 7.4 0.043 14.4 0.7 2.3 2 0 0 2 2 2 2 Apg6 coiled-coil region TPD52 PF04201.15 RKP01178.1 - 0.35 10.5 2.5 0.28 10.8 0.5 1.7 2 0 0 2 2 2 0 Tumour protein D52 family eIF-6 PF01912.18 RKP01179.1 - 3.9e-80 267.9 0.5 4.6e-80 267.7 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family CMS1 PF14617.6 RKP01180.1 - 1.7e-16 60.3 0.7 3e-13 49.7 0.0 3.0 3 0 0 3 3 3 3 U3-containing 90S pre-ribosomal complex subunit FoP_duplication PF13865.6 RKP01180.1 - 5.4 7.6 12.0 13 6.4 12.0 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 GDPD PF03009.17 RKP01181.1 - 2.8e-33 115.8 0.0 3e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family BTV_NS2 PF04514.12 RKP01183.1 - 0.51 9.1 2.1 0.76 8.5 2.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spt5_N PF11942.8 RKP01183.1 - 0.94 10.5 8.8 2.4 9.2 6.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal LZ_Tnp_IS66 PF13007.7 RKP01183.1 - 4.5 8.1 10.7 3.1 8.6 1.0 3.2 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Glyco_trans_2_3 PF13632.6 RKP01185.1 - 4.3e-27 95.3 4.1 4.3e-27 95.3 4.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKP01185.1 - 3.8e-15 56.4 0.2 5.3e-15 55.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RKP01185.1 - 0.17 11.4 0.0 0.62 9.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 Peptidase_S8 PF00082.22 RKP01186.1 - 2.3e-37 128.9 0.2 3.6e-37 128.2 0.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RKP01186.1 - 1.1e-13 51.0 0.1 2.7e-13 49.7 0.1 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain Cytochrom_B561 PF03188.16 RKP01187.1 - 9.8e-09 35.5 5.6 2.3e-08 34.3 5.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 RKP01187.1 - 0.00019 21.6 1.0 0.16 12.1 0.0 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF4079) DUF418 PF04235.12 RKP01187.1 - 0.023 14.6 8.9 0.1 12.6 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF418) Ferric_reduct PF01794.19 RKP01187.1 - 0.16 12.1 8.0 0.075 13.2 3.9 2.3 1 1 0 2 2 2 0 Ferric reductase like transmembrane component Pkinase PF00069.25 RKP01188.1 - 2.5e-51 174.6 0.0 1.1e-50 172.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01188.1 - 3e-20 72.6 0.0 4.1e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKP01188.1 - 5.5e-05 23.2 0.2 0.00023 21.2 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKP01188.1 - 0.011 15.4 0.3 0.027 14.1 0.1 1.6 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.14 RKP01188.1 - 0.026 13.9 0.1 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RKP01188.1 - 0.08 12.6 0.4 2.6 7.6 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 RKP01188.1 - 0.12 11.9 0.2 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Reprolysin_4 PF13583.6 RKP01189.1 - 1.1e-33 116.6 1.7 1.8e-33 115.9 1.7 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 RKP01189.1 - 2.8e-33 115.8 5.2 2.8e-33 115.8 5.2 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 RKP01189.1 - 1.1e-30 107.0 1.9 1.1e-30 107.0 1.9 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 RKP01189.1 - 7.7e-17 61.9 30.7 7.7e-17 61.9 30.7 4.7 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 RKP01189.1 - 6.6e-11 42.8 0.7 3.3e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like eIF-5_eIF-2B PF01873.17 RKP01190.1 - 4.1e-40 136.3 0.1 7.1e-40 135.5 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 RKP01190.1 - 6.7e-21 74.2 0.1 6.7e-21 74.2 0.1 3.2 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon MCCD1 PF15707.5 RKP01190.1 - 2.2 8.8 5.1 0.54 10.8 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 RrnaAD PF00398.20 RKP01191.1 - 0.22 10.6 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RabGAP-TBC PF00566.18 RKP01192.1 - 1.7e-36 125.9 9.0 9.2e-36 123.5 2.8 2.6 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Tyrosinase PF00264.20 RKP01193.1 - 1.6e-21 77.6 6.4 2.3e-11 44.4 0.4 2.9 1 1 1 2 2 2 2 Common central domain of tyrosinase Ten1_2 PF15490.6 RKP01194.1 - 6.9e-06 25.8 0.0 3.8e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Exo_endo_phos PF03372.23 RKP01195.1 - 3.7e-13 49.5 0.1 6.3e-13 48.8 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 RKP01196.1 - 9.3e-75 251.4 0.0 1.2e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01196.1 - 2.7e-34 118.6 0.0 3.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RKP01196.1 - 1.2e-12 48.3 4.1 3e-12 47.0 4.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 RKP01196.1 - 8.9e-06 24.9 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKP01196.1 - 0.0056 16.0 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 RKP01196.1 - 0.036 13.7 0.1 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKP01196.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family KA1 PF02149.19 RKP01197.1 - 8.7e-19 67.1 0.1 1.5e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.25 RKP01198.1 - 3.7e-74 249.4 0.0 4.6e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01198.1 - 2.1e-41 141.9 0.0 3.2e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01198.1 - 1.5e-09 37.6 0.0 2.3e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP01198.1 - 0.0073 15.7 0.1 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP01198.1 - 0.031 13.2 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RKP01198.1 - 0.037 13.9 0.3 0.15 11.9 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 RKP01199.1 - 2.3e-25 89.3 66.8 3.3e-19 69.0 40.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RKP01199.1 - 6.9e-07 28.5 24.7 7.1e-07 28.4 2.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter SH3_9 PF14604.6 RKP01200.1 - 4.3e-05 23.3 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain WSC PF01822.19 RKP01200.1 - 5.5e-05 23.3 8.5 9.7e-05 22.5 8.5 1.4 1 0 0 1 1 1 1 WSC domain SH3_2 PF07653.17 RKP01200.1 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01200.1 - 0.00089 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF1180 PF06679.12 RKP01200.1 - 0.027 14.9 7.4 0.046 14.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF4690 PF15756.5 RKP01200.1 - 0.061 13.9 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Hydrophobin PF01185.18 RKP01201.1 - 1e-06 29.2 6.2 1.8e-06 28.5 6.2 1.4 1 1 0 1 1 1 1 Fungal hydrophobin DUF1996 PF09362.10 RKP01202.1 - 1.8e-52 178.7 0.0 2.6e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TMEM247 PF15444.6 RKP01203.1 - 0.053 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 tRNA-synt_1 PF00133.22 RKP01204.1 - 7e-36 123.7 0.3 1.4e-20 73.1 0.1 5.1 3 1 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RKP01204.1 - 4.9e-30 104.6 0.0 1.4e-22 80.0 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 RKP01204.1 - 0.0032 16.4 0.0 0.62 8.9 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (K) DNA_ligase_ZBD PF03119.16 RKP01204.1 - 0.035 14.1 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1e PF01406.19 RKP01204.1 - 0.12 11.7 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain TP_methylase PF00590.20 RKP01205.1 - 5.8e-10 39.5 9.0 1.2e-09 38.5 9.0 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Herpes_capsid PF06112.11 RKP01205.1 - 1.1 9.3 6.6 2.3 8.3 6.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-C2H2 PF00096.26 RKP01206.1 - 1.1e-09 38.2 10.5 1.2e-05 25.5 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKP01206.1 - 1.7e-06 28.2 7.6 3.5e-06 27.2 0.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKP01206.1 - 4e-06 27.2 8.2 0.0067 17.2 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RKP01206.1 - 0.0017 18.3 4.6 0.01 15.8 0.6 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Med3 PF11593.8 RKP01206.1 - 0.0063 15.7 3.5 0.0084 15.3 3.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal zf-C2H2_8 PF15909.5 RKP01206.1 - 0.019 15.2 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 RKP01206.1 - 0.031 13.9 0.8 0.44 10.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 RKP01206.1 - 0.052 14.0 1.5 1.5 9.3 0.1 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 RKP01206.1 - 0.085 13.5 0.5 16 6.2 0.1 2.2 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 RKP01206.1 - 0.086 13.6 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 RKP01206.1 - 0.091 12.9 1.2 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-MYST PF17772.1 RKP01206.1 - 0.17 11.5 0.4 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 RKP01206.1 - 0.85 9.4 8.9 0.17 11.7 0.9 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 RKP01206.1 - 1.3 9.0 6.4 0.7 9.9 0.5 2.2 1 1 0 2 2 2 0 SprT-like zinc ribbon domain zf-CCCH PF00642.24 RKP01207.1 - 1.2e-18 66.5 16.6 1.4e-13 50.4 2.6 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RKP01207.1 - 2.2e-10 40.2 14.4 2e-07 30.8 4.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 RKP01207.1 - 5.9e-06 26.0 12.6 9.3e-06 25.3 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RKP01207.1 - 0.011 16.2 0.6 0.011 16.2 0.6 2.7 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 RKP01207.1 - 0.034 14.9 11.5 0.68 10.7 1.4 2.1 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 RKP01207.1 - 4.7 7.8 10.8 5.2e+02 1.3 10.9 2.2 1 1 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region PGI PF00342.19 RKP01209.1 - 7.6e-235 780.1 0.0 8.6e-235 779.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4148 PF13663.6 RKP01209.1 - 9.7e-06 25.7 0.3 2.7e-05 24.2 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4148) MTBP_N PF14918.6 RKP01209.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 MDM2-binding Hydrophobin PF01185.18 RKP01210.1 - 1.1e-10 42.0 10.3 1.4e-10 41.7 10.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin zf-C2H2 PF00096.26 RKP01211.1 - 4.3e-05 23.7 19.7 0.018 15.5 0.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP01211.1 - 0.00022 21.8 18.8 0.1 13.5 0.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger DUF2722 PF10846.8 RKP01211.1 - 0.0014 17.6 11.7 0.0014 17.6 11.7 3.6 3 1 0 3 3 2 2 Protein of unknown function (DUF2722) SET PF00856.28 RKP01211.1 - 0.0047 17.3 4.4 0.76 10.1 0.4 2.6 2 0 0 2 2 2 2 SET domain zf-C2H2_6 PF13912.6 RKP01211.1 - 0.0047 16.9 5.2 0.26 11.3 0.0 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP01211.1 - 0.017 15.5 1.6 0.017 15.5 1.6 3.3 4 0 0 4 4 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 RKP01211.1 - 0.67 9.8 5.7 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Spt20 PF12090.8 RKP01211.1 - 2 8.0 61.2 0.099 12.2 21.8 3.3 3 0 0 3 3 3 0 Spt20 family zf-met PF12874.7 RKP01211.1 - 2.6 8.6 7.7 6.4 7.3 0.1 3.6 4 0 0 4 4 3 0 Zinc-finger of C2H2 type FHIPEP PF00771.20 RKP01211.1 - 3.1 6.1 12.0 0.69 8.3 0.9 2.2 2 0 0 2 2 2 0 FHIPEP family Macoilin PF09726.9 RKP01211.1 - 4.4 5.7 14.0 3.9 5.9 5.8 2.2 2 0 0 2 2 2 0 Macoilin family RLL PF10036.9 RKP01211.1 - 7.1 6.4 17.9 3.9 7.2 4.5 3.0 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein Peptidase_S49_N PF08496.10 RKP01211.1 - 9.5 6.3 8.7 4.8 7.2 1.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Acyl-CoA_dh_1 PF00441.24 RKP01212.1 - 3.3e-31 108.5 0.9 5e-31 107.9 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKP01212.1 - 1.1e-17 64.1 0.1 1.8e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RKP01212.1 - 1.2e-11 45.2 0.0 2.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RKP01212.1 - 7.5e-10 39.2 0.2 1.4e-09 38.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RGS PF00615.19 RKP01213.1 - 0.017 15.4 0.3 0.034 14.4 0.3 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain DMRL_synthase PF00885.19 RKP01214.1 - 1.5e-48 164.2 0.3 1.8e-48 164.0 0.3 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Pkinase PF00069.25 RKP01217.1 - 1.4e-62 211.4 0.0 1.9e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01217.1 - 3.2e-32 111.8 0.0 3.9e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01217.1 - 1.7e-07 30.8 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP01217.1 - 0.00012 21.0 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RKP01217.1 - 0.0073 15.3 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP01217.1 - 0.0082 15.5 0.7 0.013 14.8 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RKP01217.1 - 0.02 14.5 0.3 2.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKP01217.1 - 0.026 14.4 0.3 0.052 13.5 0.3 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 RKP01218.1 - 9.7e-64 215.3 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01218.1 - 7.8e-35 120.4 0.0 9.9e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01218.1 - 5.2e-09 35.8 0.0 7.3e-09 35.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP01218.1 - 0.00073 18.9 0.3 0.0011 18.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP01218.1 - 0.00088 19.3 0.5 0.0065 16.4 0.4 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP01218.1 - 0.00096 18.2 0.3 0.0013 17.8 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 RKP01218.1 - 0.021 13.6 0.1 0.035 12.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RKP01218.1 - 0.033 13.8 0.0 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 RKP01218.1 - 0.097 11.7 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Dus PF01207.17 RKP01220.1 - 4e-50 170.7 0.1 5.2e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DnaJ PF00226.31 RKP01221.1 - 1.1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain XPA_C PF05181.12 RKP01222.1 - 8.3e-21 73.7 0.1 1.5e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 RKP01222.1 - 0.00012 22.1 1.4 0.0002 21.3 1.4 1.4 1 0 0 1 1 1 1 XPA protein N-terminal SPT6_acidic PF14632.6 RKP01222.1 - 0.014 15.9 1.7 0.014 15.9 1.7 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 zf-RING_7 PF02591.15 RKP01222.1 - 0.15 12.3 3.6 1 9.6 0.1 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF4710 PF15828.5 RKP01222.1 - 4.1 7.6 6.3 10 6.3 0.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4710) Peptidase_M28 PF04389.17 RKP01223.1 - 1.8e-36 125.7 0.2 3.1e-36 124.9 0.2 1.4 1 1 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 RKP01223.1 - 0.035 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Choline_transpo PF04515.12 RKP01224.1 - 5.8e-76 255.8 42.3 5.8e-76 255.8 42.3 2.1 3 0 0 3 3 3 1 Plasma-membrane choline transporter Pcc1 PF09341.10 RKP01225.1 - 2.7e-21 75.5 0.1 3.3e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 PIH1_CS PF18201.1 RKP01226.1 - 0.063 13.7 0.0 0.22 12.0 0.0 1.8 2 1 0 2 2 2 0 PIH1 CS-like domain JAB PF01398.21 RKP01227.1 - 7.4e-31 106.6 0.0 1e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 RKP01227.1 - 1.1e-09 39.1 0.1 0.00065 20.6 0.0 2.3 1 1 1 2 2 2 2 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 RKP01227.1 - 8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 RKP01227.1 - 0.051 13.6 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) CinA PF02464.17 RKP01227.1 - 0.14 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Competence-damaged protein PolyA_pol PF01743.20 RKP01228.1 - 5.9e-24 84.9 0.0 9.2e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain Dev_Cell_Death PF10539.9 RKP01228.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Development and cell death domain WD40 PF00400.32 RKP01229.1 - 0.32 11.9 5.1 29 5.8 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat FAM76 PF16046.5 RKP01230.1 - 0.029 13.7 0.8 0.031 13.6 0.8 1.1 1 0 0 1 1 1 0 FAM76 protein TolA_bind_tri PF16331.5 RKP01230.1 - 0.073 13.2 2.1 0.13 12.4 1.3 1.8 1 1 0 1 1 1 0 TolA binding protein trimerisation Cortex-I_coil PF09304.10 RKP01230.1 - 0.2 11.9 3.0 0.55 10.5 3.0 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil Nramp PF01566.18 RKP01232.1 - 1.9e-101 339.6 26.9 5.9e-101 338.0 26.9 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein LRR19-TM PF15176.6 RKP01232.1 - 0.036 14.1 1.2 3.6 7.6 0.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Prp19 PF08606.11 RKP01233.1 - 1.2e-28 98.9 3.9 1.7e-28 98.4 2.4 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 RKP01233.1 - 8.4e-12 45.4 13.5 0.0033 18.2 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01233.1 - 1.5e-10 41.2 0.0 0.14 12.5 0.0 5.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 RKP01233.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 RKP01233.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger ABC1 PF03109.16 RKP01234.1 - 2.2e-24 85.9 0.0 3.9e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 RKP01234.1 - 0.055 13.4 0.3 0.63 9.9 0.0 2.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family WGG PF10273.9 RKP01235.1 - 1.8e-08 34.9 0.1 1.8e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 TFIIA PF03153.13 RKP01235.1 - 0.0024 18.0 3.0 0.0028 17.7 3.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FinO_N PF12602.8 RKP01235.1 - 0.11 12.8 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Fertility inhibition protein N terminal AF-4 PF05110.13 RKP01235.1 - 0.17 10.0 0.2 0.22 9.5 0.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 RKP01235.1 - 0.52 10.0 4.7 0.63 9.7 4.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Kelch_1 PF01344.25 RKP01236.1 - 4.7e-11 42.1 1.5 0.0014 18.1 1.5 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 RKP01236.1 - 3.7e-09 36.5 0.6 0.0096 16.2 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 RKP01236.1 - 2.3e-08 33.9 2.5 0.0036 17.3 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RKP01236.1 - 2.9e-06 27.0 2.6 1.4 9.0 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 RKP01236.1 - 0.00036 20.7 0.0 0.00036 20.7 0.0 5.6 7 1 0 7 7 7 2 Galactose oxidase, central domain Zw10 PF06248.13 RKP01237.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Pep3_Vps18 PF05131.14 RKP01238.1 - 3.1e-32 111.5 0.0 6.1e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 RKP01238.1 - 3.3e-06 27.0 0.1 6e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.9 RKP01238.1 - 0.00052 20.4 0.0 0.0064 16.9 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 RKP01238.1 - 0.00085 19.6 1.9 0.00085 19.6 1.9 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 RKP01238.1 - 0.00094 19.4 0.8 0.0024 18.1 0.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 RKP01238.1 - 0.0025 17.8 1.7 0.0053 16.7 1.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RKP01238.1 - 0.023 14.8 1.3 0.044 13.8 0.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cadherin_2 PF08266.12 RKP01238.1 - 0.047 13.5 0.1 0.2 11.5 0.1 2.1 1 0 0 1 1 1 0 Cadherin-like RPN1_RPN2_N PF17781.1 RKP01238.1 - 0.13 11.7 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Sigma70_r1_1 PF03979.14 RKP01238.1 - 0.15 12.2 0.2 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 zf-C3HC4 PF00097.25 RKP01238.1 - 0.52 10.2 2.3 1.2 9.0 2.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 RKP01238.1 - 0.89 9.3 3.4 0.8 9.4 1.1 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_2 PF13923.6 RKP01238.1 - 1.4 8.9 6.4 0.28 11.1 2.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP01238.1 - 2.6 8.1 4.4 0.79 9.7 1.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 RKP01238.1 - 6.8 6.5 11.7 0.53 10.1 6.2 2.0 2 0 0 2 2 2 0 RING-like zinc finger WD40 PF00400.32 RKP01239.1 - 2.9e-46 154.5 25.8 1.4e-08 35.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01239.1 - 5.4e-12 45.8 1.9 0.19 12.0 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP01239.1 - 3.2e-06 26.3 0.2 1.3 7.9 0.0 4.4 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKP01239.1 - 3.2e-05 22.8 9.8 0.045 12.4 0.2 4.7 4 1 2 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RKP01239.1 - 0.00096 19.1 0.3 0.0051 16.7 0.1 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 RKP01239.1 - 0.0083 15.2 0.2 0.92 8.5 0.0 3.1 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) bMG3 PF11974.8 RKP01239.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain IKI3 PF04762.12 RKP01239.1 - 0.13 10.2 0.0 1 7.3 0.0 2.2 2 1 1 3 3 3 0 IKI3 family WD40_like PF17005.5 RKP01239.1 - 0.22 10.8 0.0 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Ank_2 PF12796.7 RKP01240.1 - 6.7e-05 23.4 0.1 0.00056 20.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 RKP01240.1 - 0.00021 21.6 4.5 0.062 13.8 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 RKP01240.1 - 0.00034 20.9 0.2 0.00034 20.9 0.2 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP01240.1 - 0.0025 18.2 5.3 0.95 10.2 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 RKP01240.1 - 0.035 14.7 0.6 0.15 12.7 0.1 2.4 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Solute_trans_a PF03619.16 RKP01241.1 - 4.2e-66 223.2 10.8 4.7e-66 223.0 10.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Transket_pyr PF02779.24 RKP01242.1 - 6.3e-45 153.0 0.1 9.2e-45 152.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RKP01242.1 - 7.2e-30 103.4 0.0 1.3e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PapC_C PF13953.6 RKP01242.1 - 0.032 14.1 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 PapC C-terminal domain Ribosomal_S5 PF00333.20 RKP01242.1 - 0.4 10.7 2.2 0.35 10.9 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Acyl-CoA_dh_1 PF00441.24 RKP01243.1 - 3.8e-49 166.8 4.3 3.8e-49 166.8 4.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKP01243.1 - 4.4e-27 94.1 0.1 9.4e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RKP01243.1 - 6.2e-26 91.3 0.2 1.8e-25 89.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RKP01243.1 - 2.8e-19 69.7 2.8 5.7e-19 68.7 2.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 RKP01243.1 - 0.00011 21.9 0.0 0.00038 20.2 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Hydrophobin PF01185.18 RKP01244.1 - 0.0045 17.6 10.6 0.0069 17.0 10.6 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Ferric_reduct PF01794.19 RKP01247.1 - 1.1e-20 74.0 16.3 1.1e-20 74.0 16.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RKP01247.1 - 1e-11 45.2 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RKP01247.1 - 4.2e-10 39.7 0.0 8.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF4131 PF13567.6 RKP01247.1 - 1.4 8.6 10.8 0.32 10.7 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4405 PF14358.6 RKP01247.1 - 3.2 8.4 23.8 0.3 11.6 1.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF4205 PF13898.6 RKP01250.1 - 3.2e-23 82.2 0.0 1.9e-12 46.8 0.2 3.8 3 1 0 3 3 3 2 Domain of unknown function (DUF4205) CBS PF00571.28 RKP01251.1 - 3.3e-28 97.9 4.1 6.7e-08 32.9 0.0 4.4 4 0 0 4 4 4 4 CBS domain Rep_fac-A_C PF08646.10 RKP01252.1 - 4.9e-53 178.8 0.5 2.3e-49 166.9 0.1 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 RKP01252.1 - 2.1e-30 104.5 0.1 8.1e-30 102.6 0.1 2.0 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 RKP01252.1 - 3.9e-12 46.0 0.3 1.3e-09 37.9 0.0 3.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 RKP01252.1 - 0.011 15.4 0.0 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 DUF2141 PF09912.9 RKP01252.1 - 0.011 15.6 0.1 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) DUF3127 PF11325.8 RKP01252.1 - 0.012 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) MMR_HSR1_Xtn PF16897.5 RKP01253.1 - 1.5e-42 143.9 0.4 6.9e-42 141.8 0.4 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 RKP01253.1 - 2.1e-21 75.7 0.1 3.6e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 RKP01253.1 - 4.1e-20 72.0 0.0 1.2e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP01253.1 - 1.1e-11 44.6 0.0 8.5e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RKP01253.1 - 0.0079 16.3 0.1 2.2 8.3 0.1 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 RKP01253.1 - 0.035 13.7 0.1 4.2 6.8 0.0 3.2 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 RKP01253.1 - 0.082 11.9 0.6 0.23 10.4 0.3 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FGGY_N PF00370.21 RKP01254.1 - 2.9e-54 184.2 0.0 1.5e-52 178.6 0.0 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 RKP01254.1 - 1.5e-48 165.1 3.2 3.2e-48 164.1 3.2 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Arm PF00514.23 RKP01255.1 - 9.8e-47 155.6 32.2 0.00077 19.4 0.0 14.2 13 1 0 14 14 14 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKP01255.1 - 1e-10 41.9 24.3 1.3e-05 25.5 1.5 7.5 2 2 6 8 8 8 2 HEAT repeats Adaptin_N PF01602.20 RKP01255.1 - 1.8e-09 36.7 4.7 0.00016 20.4 0.0 3.2 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 RKP01255.1 - 1.2e-06 28.9 17.0 0.00066 20.1 0.4 7.5 6 1 1 7 7 7 3 HEAT-like repeat RICTOR_N PF14664.6 RKP01255.1 - 0.00033 19.8 2.7 0.00084 18.4 0.3 2.8 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term Cnd1 PF12717.7 RKP01255.1 - 0.0014 18.7 0.3 1.7 8.7 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 RKP01255.1 - 0.0022 16.2 4.1 0.14 10.3 2.7 3.0 2 1 1 3 3 3 2 Kinesin-associated protein (KAP) DUF727 PF05303.12 RKP01255.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Arm_2 PF04826.13 RKP01255.1 - 0.014 14.9 5.2 3.1 7.2 0.7 4.5 3 2 2 5 5 5 0 Armadillo-like Alkyl_sulf_dimr PF14863.6 RKP01255.1 - 0.064 13.7 0.2 0.26 11.7 0.2 2.0 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation HEAT PF02985.22 RKP01255.1 - 0.081 13.2 27.6 0.65 10.4 0.2 8.6 11 0 0 11 11 10 0 HEAT repeat Phage_TAC_12 PF12363.8 RKP01255.1 - 0.09 13.2 0.1 9.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC E3_UbLigase_R4 PF13764.6 RKP01255.1 - 0.19 9.9 0.7 0.41 8.8 0.7 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 UNC45-central PF11701.8 RKP01255.1 - 0.19 11.6 11.3 69 3.4 5.3 5.0 2 2 2 4 4 4 0 Myosin-binding striated muscle assembly central V-ATPase_H_N PF03224.14 RKP01255.1 - 0.24 10.6 1.4 2.3 7.4 0.9 2.9 2 1 0 2 2 2 0 V-ATPase subunit H IFRD PF05004.13 RKP01255.1 - 0.28 10.3 8.1 0.32 10.1 1.0 3.5 2 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Choline_transpo PF04515.12 RKP01256.1 - 1.3e-36 126.5 15.9 1.3e-36 126.5 15.9 2.0 4 0 0 4 4 4 1 Plasma-membrane choline transporter L6_membrane PF05805.12 RKP01256.1 - 2.2 7.8 8.1 0.12 12.0 0.8 2.4 2 1 0 2 2 2 0 L6 membrane protein Palm_thioest PF02089.15 RKP01257.1 - 5.1e-51 173.8 0.0 8.4e-50 169.9 0.0 2.1 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF3611 PF12263.8 RKP01257.1 - 0.013 15.4 1.3 0.013 15.4 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) NDUF_B12 PF08122.12 RKP01257.1 - 0.014 15.4 2.0 4.6 7.4 0.1 2.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family 4HB_MCP_1 PF12729.7 RKP01257.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SPX PF03105.19 RKP01257.1 - 1.3 8.9 7.9 3 7.7 7.8 1.6 1 1 0 1 1 1 0 SPX domain HATPase_c PF02518.26 RKP01258.1 - 8.8e-33 113.2 0.0 1.4e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RKP01258.1 - 1.1e-19 70.6 0.1 2.1e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RKP01258.1 - 0.00096 19.1 1.0 0.0018 18.2 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Herpes_capsid PF06112.11 RKP01258.1 - 6.5 6.8 9.2 11 6.1 9.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NDUF_B8 PF05821.11 RKP01259.1 - 3e-08 33.7 1.1 1.3e-07 31.7 1.1 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Septin PF00735.18 RKP01260.1 - 6.8e-26 91.2 0.0 1.3e-24 87.0 0.0 2.4 1 1 0 1 1 1 1 Septin SH3_9 PF14604.6 RKP01260.1 - 8.5e-11 41.5 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01260.1 - 2.2e-08 33.6 0.0 3.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Dynamin_N PF00350.23 RKP01260.1 - 0.0003 20.9 0.3 0.27 11.3 0.0 3.2 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 RKP01260.1 - 0.0023 18.1 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RKP01260.1 - 0.0035 17.4 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RKP01260.1 - 0.0081 16.6 0.1 0.0081 16.6 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 RKP01260.1 - 0.016 15.7 3.0 0.054 14.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 RKP01260.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SH3_2 PF07653.17 RKP01260.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain AAA_22 PF13401.6 RKP01260.1 - 0.031 14.6 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RKP01260.1 - 0.039 13.9 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase TniB PF05621.11 RKP01260.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ras PF00071.22 RKP01260.1 - 0.085 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras family FAM70 PF14967.6 RKP01260.1 - 0.79 9.1 14.3 2.1 7.7 14.3 1.7 1 0 0 1 1 1 0 FAM70 protein Macoilin PF09726.9 RKP01260.1 - 1.1 7.8 14.1 2.1 6.8 14.1 1.4 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 RKP01260.1 - 1.1 6.3 16.7 1.5 5.9 16.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 RKP01260.1 - 3.4 5.8 22.4 5.1 5.2 22.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 RKP01260.1 - 3.9 7.3 28.8 2.7 7.8 20.9 2.3 2 0 0 2 2 2 0 SPX domain DUF1387 PF07139.11 RKP01260.1 - 9.1 5.9 16.8 20 4.8 16.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ctr PF04145.15 RKP01261.1 - 5.9e-26 91.9 0.0 9.3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family LRR_9 PF14580.6 RKP01262.1 - 1.7e-48 164.4 0.2 2.1e-48 164.1 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RKP01262.1 - 6.5e-11 42.3 6.2 3.2e-05 24.2 0.2 3.5 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP01262.1 - 8.3e-09 35.1 11.8 6.5e-06 25.8 2.4 2.4 1 1 2 3 3 3 3 Leucine rich repeat FlgM PF04316.13 RKP01262.1 - 0.08 13.3 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Asn_synthase PF00733.21 RKP01263.1 - 1.6e-22 80.7 0.2 4.7e-14 52.8 0.2 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_6 PF13522.6 RKP01263.1 - 0.0096 16.1 0.0 0.061 13.5 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RKP01263.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain DUF1752 PF08550.10 RKP01264.1 - 1e-11 44.5 1.4 2e-11 43.5 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ribosomal_S14 PF00253.21 RKP01265.1 - 3.1e-14 52.5 2.2 3.4e-14 52.3 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Peptidase_M13 PF01431.21 RKP01266.1 - 4.4e-51 173.4 0.0 6.1e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 RKP01266.1 - 1.4e-24 87.6 0.0 2e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 DUF4366 PF14283.6 RKP01267.1 - 0.036 14.1 0.4 0.046 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tic110 PF16940.5 RKP01267.1 - 3.1 6.2 4.2 3.5 6.0 4.2 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter UCH PF00443.29 RKP01268.1 - 1.1e-68 231.5 0.0 1.3e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP01268.1 - 7.3e-16 58.7 0.0 1.1e-13 51.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 RKP01268.1 - 0.03 14.2 0.3 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 RKP01268.1 - 0.53 10.2 2.5 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 RKP01268.1 - 0.97 9.4 4.6 9.2 6.3 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain COG6 PF06419.11 RKP01269.1 - 8.5e-59 199.3 0.1 2.8e-55 187.7 0.3 3.5 3 1 0 3 3 3 2 Conserved oligomeric complex COG6 AFOR_N PF02730.15 RKP01269.1 - 0.09 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Fmp27_WPPW PF10359.9 RKP01269.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2457 PF10446.9 RKP01269.1 - 0.5 9.5 8.5 1.1 8.3 8.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ADIP PF11559.8 RKP01269.1 - 1.8 8.7 5.3 0.3 11.2 1.0 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Hydrolase_like PF13242.6 RKP01270.1 - 8.6e-10 38.5 3.6 2e-09 37.4 0.4 2.8 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RKP01270.1 - 7.6e-07 29.2 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKP01270.1 - 0.00017 22.0 1.6 0.00025 21.4 1.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 7tm_3 PF00003.22 RKP01272.1 - 0.0046 16.7 1.0 0.0046 16.7 1.0 2.0 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR T3SS_TC PF06511.11 RKP01275.1 - 3 7.2 11.3 0.048 13.1 2.8 2.3 2 0 0 2 2 2 0 Type III secretion systems tip complex components MRP-L27 PF09809.9 RKP01276.1 - 1.4e-15 57.1 0.4 1.6e-15 57.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pkinase PF00069.25 RKP01277.1 - 1.3e-59 201.7 0.0 1.5e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01277.1 - 1.4e-42 145.7 0.0 1.7e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01277.1 - 4.9e-06 26.1 0.0 0.0037 16.6 0.0 2.3 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RKP01277.1 - 0.00094 18.1 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKP01277.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP01277.1 - 0.27 10.1 0.0 0.39 9.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MgtE PF01769.16 RKP01278.1 - 1.1e-16 61.4 6.6 1.1e-16 61.4 6.6 1.8 2 0 0 2 2 2 1 Divalent cation transporter RTT107_BRCT_5 PF16770.5 RKP01279.1 - 1.3e-09 37.9 0.0 3.4e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 RKP01279.1 - 1.2e-07 32.1 0.0 0.016 15.6 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain FHA PF00498.26 RKP01279.1 - 8e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 RKP01279.1 - 2.9e-05 24.4 0.0 0.0054 17.1 0.0 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IML1 PF12257.8 RKP01280.1 - 1.7e-101 339.2 0.0 2.4e-101 338.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 RKP01280.1 - 6.2e-21 74.2 0.3 1.3e-20 73.2 0.3 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Exonuc_VII_L PF02601.15 RKP01281.1 - 4 6.9 17.1 7 6.1 17.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MAJIN PF15077.6 RKP01281.1 - 7.2 6.3 10.4 15 5.2 10.4 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein Neur_chan_memb PF02932.16 RKP01281.1 - 8.8 6.3 9.0 20 5.2 9.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.32 RKP01282.1 - 2.7e-08 34.4 7.0 0.35 11.8 0.0 8.2 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01282.1 - 0.00021 21.5 0.0 1.1 9.6 0.0 4.8 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_5 PF13873.6 RKP01283.1 - 2.6e-05 24.2 0.6 6.1e-05 23.0 0.6 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 RKP01283.1 - 0.0018 18.4 0.2 0.0028 17.8 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKP01283.1 - 0.0023 18.1 0.6 0.0023 18.1 0.6 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain EIF4E-T PF10477.9 RKP01283.1 - 0.49 9.2 39.2 1.5 7.6 11.1 2.2 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RIFIN PF02009.16 RKP01283.1 - 1.6 8.6 15.7 8.3 6.2 0.4 2.4 2 0 0 2 2 2 0 Rifin Exonuc_VII_L PF02601.15 RKP01283.1 - 2.6 7.6 37.3 0.87 9.1 16.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit FapA PF03961.13 RKP01283.1 - 5.8 5.4 13.7 0.42 9.2 0.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A BRO1 PF03097.18 RKP01284.1 - 2.7e-115 385.3 2.2 1.4e-113 379.7 0.1 2.7 3 0 0 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RKP01284.1 - 8.8e-25 87.6 5.6 2.1e-24 86.4 5.6 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2383 PF09537.10 RKP01284.1 - 0.028 14.7 6.5 0.039 14.3 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) TSA PF03249.13 RKP01284.1 - 0.039 12.7 3.7 0.37 9.5 2.7 2.2 2 0 0 2 2 2 0 Type specific antigen DUF4070 PF13282.6 RKP01284.1 - 0.061 13.5 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Sod_Cu PF00080.20 RKP01285.1 - 0.0012 19.0 0.0 0.035 14.3 0.0 2.2 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2019 PF09450.10 RKP01285.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) HMA PF00403.26 RKP01285.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain LSM PF01423.22 RKP01286.1 - 7.8e-18 63.9 0.0 8.7e-18 63.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain rRNA_processing PF08524.11 RKP01287.1 - 0.79 9.7 11.4 0.046 13.7 3.1 2.1 2 0 0 2 2 2 0 rRNA processing Macoilin PF09726.9 RKP01287.1 - 1.5 7.3 14.0 2 6.9 14.0 1.0 1 0 0 1 1 1 0 Macoilin family zf-CCCH_3 PF15663.5 RKP01288.1 - 1.3e-14 54.3 37.5 1.4e-05 25.3 4.0 5.2 5 1 1 6 6 6 4 Zinc-finger containing family zf-CCCH PF00642.24 RKP01288.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 5.4 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RKP01288.1 - 0.17 12.0 0.1 0.17 12.0 0.1 6.2 8 1 0 8 8 8 0 Zinc finger domain Mito_carr PF00153.27 RKP01289.1 - 1.9e-38 130.3 0.2 2.8e-18 65.6 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein eIF-5_eIF-2B PF01873.17 RKP01290.1 - 2.2e-40 137.2 0.0 3.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 RKP01290.1 - 0.02 14.4 0.3 0.033 13.7 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding IF2_N PF04760.15 RKP01290.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region 2OG-FeII_Oxy_2 PF13532.6 RKP01291.1 - 3.1e-20 73.2 0.0 4.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GTP_EFTU PF00009.27 RKP01292.1 - 1e-61 207.9 0.0 1.9e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RKP01292.1 - 4.9e-42 142.5 0.3 3.2e-41 139.9 0.1 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 RKP01292.1 - 1.6e-29 101.8 0.0 3.4e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RKP01292.1 - 8.3e-23 80.2 0.0 2.4e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKP01292.1 - 2.8e-10 40.4 0.1 1.7e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RKP01292.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 RKP01292.1 - 0.0011 19.0 0.1 0.003 17.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RKP01292.1 - 0.02 14.3 0.0 0.065 12.6 0.0 1.7 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.18 RKP01292.1 - 0.068 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 RKP01292.1 - 0.076 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1949 PF09186.11 RKP01292.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) ANAPC4_WD40 PF12894.7 RKP01293.1 - 1.3e-13 51.0 0.3 0.035 14.4 0.0 6.6 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKP01293.1 - 2.1e-12 47.3 0.6 4.4 8.3 0.1 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 RKP01293.1 - 1e-05 25.5 0.0 11 5.9 0.0 5.3 4 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RKP01293.1 - 0.00026 20.8 3.9 3 7.9 0.1 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 RKP01293.1 - 0.04 13.2 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 RKP01293.1 - 0.045 11.8 0.1 11 3.8 0.0 3.6 2 1 1 4 4 4 0 IKI3 family DPPIV_N PF00930.21 RKP01293.1 - 0.57 8.9 2.0 55 2.4 0.0 3.7 3 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region AMP-binding PF00501.28 RKP01294.1 - 4.6e-85 285.7 0.1 5.9e-85 285.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKP01294.1 - 2.5e-12 47.6 0.1 7.6e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1681 PF07933.14 RKP01295.1 - 1.1e-46 158.2 0.0 1.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Tubulin PF00091.25 RKP01296.1 - 4.5e-58 196.7 0.0 6.2e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RKP01296.1 - 2.1e-18 66.7 0.0 3.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 RKP01296.1 - 0.029 13.5 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Ribosomal_S5 PF00333.20 RKP01297.1 - 5.2e-29 100.0 1.1 5.2e-29 100.0 1.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RKP01297.1 - 1.2e-23 82.3 0.0 1.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 RKP01297.1 - 2.9 8.5 12.1 6.3 7.4 12.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-H2C2_2 PF13465.6 RKP01298.1 - 7.2e-13 48.3 5.5 4e-06 27.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKP01298.1 - 2.9e-05 24.3 22.5 0.0025 18.2 3.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 RKP01298.1 - 0.00025 21.2 2.0 0.032 14.5 0.3 2.3 2 0 0 2 2 2 1 zinc-ribbon zf-C2H2_4 PF13894.6 RKP01298.1 - 0.00089 19.9 22.0 0.0088 16.8 3.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger ADK_lid PF05191.14 RKP01298.1 - 0.0076 16.2 5.1 1.7 8.7 0.3 2.9 2 1 1 3 3 3 2 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 RKP01298.1 - 0.03 14.6 9.4 0.069 13.5 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP01298.1 - 0.032 14.2 13.0 1.1 9.3 1.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ISL3 PF14690.6 RKP01298.1 - 0.037 14.7 0.4 0.037 14.7 0.4 2.4 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_11 PF16622.5 RKP01298.1 - 0.05 13.4 2.7 0.05 13.4 2.7 2.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 RKP01298.1 - 0.053 13.9 0.4 0.053 13.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc-ribbons_6 PF07191.12 RKP01298.1 - 0.057 13.4 3.7 0.22 11.5 3.7 2.0 1 1 0 1 1 1 0 zinc-ribbons FYDLN_acid PF09538.10 RKP01298.1 - 0.15 12.8 1.2 2.2 9.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) TRAF6_Z2 PF18048.1 RKP01298.1 - 0.15 12.2 3.5 4.5 7.4 0.5 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-UDP PF14569.6 RKP01298.1 - 0.46 10.6 4.2 3.1 8.0 0.4 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger Zn_ribbon_SprT PF17283.2 RKP01298.1 - 0.66 9.9 9.6 2.2 8.2 1.9 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Prok-RING_1 PF14446.6 RKP01298.1 - 0.74 9.8 9.8 7.6 6.6 0.3 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.7 RKP01298.1 - 5.9 6.9 11.3 5.1 7.1 1.9 2.5 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Myb_DNA-binding PF00249.31 RKP01299.1 - 1.4e-39 134.0 6.5 4.1e-15 55.7 2.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKP01299.1 - 1.6e-30 105.1 0.0 8.2e-11 42.0 0.0 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 RKP01299.1 - 0.0035 17.4 2.0 0.8 9.8 0.0 3.0 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 RKP01299.1 - 0.14 12.5 4.1 10 6.5 0.9 3.7 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain DUF3067 PF11267.8 RKP01300.1 - 0.05 14.2 0.1 33 5.1 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3067) GTP_EFTU PF00009.27 RKP01301.1 - 3.8e-58 196.3 0.3 5.3e-58 195.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RKP01301.1 - 8.4e-28 96.9 0.0 1.7e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RKP01301.1 - 1.1e-19 70.6 4.0 3.1e-19 69.1 4.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RKP01301.1 - 2.9e-05 24.1 0.0 6.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 RKP01301.1 - 0.00097 18.8 1.1 0.0014 18.3 0.1 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 RKP01301.1 - 0.013 15.5 0.1 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 RKP01301.1 - 0.036 13.8 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tyrosinase PF00264.20 RKP01302.1 - 1.3e-32 113.9 3.7 2.6e-31 109.6 3.7 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase Ricin_B_lectin PF00652.22 RKP01302.1 - 3.9e-09 36.8 0.2 2e-08 34.6 0.0 2.2 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain RFC1 PF08519.12 RKP01303.1 - 3.7e-39 134.4 0.0 2.5e-38 131.7 0.0 2.4 2 1 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 RKP01303.1 - 4.4e-13 49.8 0.1 3.1e-12 47.1 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 RKP01303.1 - 1.2e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 RKP01303.1 - 3.3e-05 23.9 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 RKP01303.1 - 0.00043 20.1 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RKP01303.1 - 0.00043 20.3 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKP01303.1 - 0.00045 20.6 3.1 0.0014 19.0 0.0 3.1 4 1 1 5 5 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 RKP01303.1 - 0.003 17.7 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RKP01303.1 - 0.007 15.8 0.5 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RKP01303.1 - 0.011 15.7 0.0 0.038 13.9 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 RKP01303.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKP01303.1 - 0.022 14.3 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 RKP01303.1 - 0.024 14.9 0.0 1.1 9.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 RKP01303.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PTCB-BRCT PF12738.7 RKP01303.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain RNA_helicase PF00910.22 RKP01303.1 - 0.075 13.4 0.0 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_assoc_2 PF16193.5 RKP01303.1 - 0.075 13.4 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain Zeta_toxin PF06414.12 RKP01303.1 - 0.083 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 RKP01303.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RKP01303.1 - 0.21 11.5 0.0 3.9 7.3 0.0 2.3 1 1 1 2 2 2 0 NTPase DUF4611 PF15387.6 RKP01303.1 - 0.64 10.3 2.9 2.1 8.6 2.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) UAA PF08449.11 RKP01304.1 - 4.2e-47 160.8 18.2 5.1e-47 160.5 18.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 RKP01304.1 - 4.4e-05 23.7 25.8 0.00069 19.8 10.4 3.0 2 1 1 3 3 3 2 EamA-like transporter family DUF485 PF04341.12 RKP01304.1 - 0.0039 17.1 2.5 0.0039 17.1 2.5 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF485 Phage_holin_2_3 PF16080.5 RKP01304.1 - 0.67 9.8 7.6 3.7 7.4 1.2 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 IFT57 PF10498.9 RKP01305.1 - 6.2e-91 305.1 0.0 7.3e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tropomyosin PF00261.20 RKP01305.1 - 0.00074 19.0 1.3 0.0011 18.3 0.7 1.5 1 1 0 1 1 1 1 Tropomyosin Baculo_PEP_C PF04513.12 RKP01305.1 - 0.0061 16.6 5.5 0.4 10.7 5.5 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 RKP01305.1 - 0.0072 15.2 0.9 0.012 14.6 0.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 RKP01305.1 - 0.012 13.9 0.2 0.016 13.5 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HAP1_N PF04849.13 RKP01305.1 - 0.024 13.8 0.9 0.064 12.4 0.2 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 RKP01305.1 - 0.025 14.6 5.9 0.59 10.2 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) T7SS_ESX_EspC PF10824.8 RKP01305.1 - 0.03 14.8 10.1 0.12 12.8 6.0 2.8 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Filament PF00038.21 RKP01305.1 - 0.031 13.9 1.1 0.051 13.2 1.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein Bcr-Abl_Oligo PF09036.10 RKP01305.1 - 0.042 13.8 1.5 3.8 7.6 0.1 3.2 2 2 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Mod_r PF07200.13 RKP01305.1 - 0.051 13.7 1.6 0.09 12.9 1.6 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein YscO PF07321.12 RKP01305.1 - 0.086 12.8 4.1 0.072 13.0 1.5 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO ATG16 PF08614.11 RKP01305.1 - 0.1 12.8 9.1 0.07 13.3 4.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.6 RKP01305.1 - 0.11 12.9 4.1 0.22 12.0 1.0 2.3 1 1 1 2 2 2 0 Snapin/Pallidin HIP1_clath_bdg PF16515.5 RKP01305.1 - 0.11 13.1 5.8 0.39 11.3 0.5 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_TATA_bd PF12325.8 RKP01305.1 - 0.25 11.6 4.7 1.1 9.4 1.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 RKP01305.1 - 0.25 11.4 4.3 0.4 10.7 0.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 RKP01305.1 - 0.45 10.9 4.4 0.98 9.9 4.4 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 RKP01305.1 - 0.69 10.0 7.4 6.1 6.9 6.7 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 RKP01305.1 - 0.78 10.0 3.4 4.1 7.7 3.4 2.3 1 1 0 1 1 1 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 RKP01305.1 - 1 9.9 4.2 18 5.9 0.9 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 RKP01305.1 - 2.2 9.0 7.5 9.7 6.9 0.2 3.3 1 1 3 4 4 4 0 SlyX DUF3138 PF11336.8 RKP01305.1 - 3.9 6.0 5.8 5.8 5.4 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) WD40 PF00400.32 RKP01306.1 - 5.6e-10 39.7 8.0 0.026 15.4 0.0 9.7 10 1 0 10 10 10 2 WD domain, G-beta repeat ERCC4 PF02732.15 RKP01307.1 - 0.00017 21.8 0.0 0.00023 21.4 0.0 1.2 1 0 0 1 1 1 1 ERCC4 domain Herpes_UL52 PF03121.15 RKP01308.1 - 1.2e-05 25.2 0.1 2.5e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Peptidase_C9 PF01707.16 RKP01308.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C9 VID27 PF08553.10 RKP01309.1 - 2.5e-113 378.8 0.0 3.1e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Peptidase_S10 PF00450.22 RKP01309.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase DUF3915 PF13054.6 RKP01310.1 - 3.4e-05 23.8 3.5 3.4e-05 23.8 3.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) TFIIA PF03153.13 RKP01311.1 - 0.0078 16.3 18.3 0.013 15.5 18.3 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 RKP01311.1 - 0.46 10.6 8.4 2.3 8.4 8.4 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Smg8_Smg9 PF10220.9 RKP01311.1 - 1.7 6.8 5.8 2.6 6.3 5.8 1.1 1 0 0 1 1 1 0 Smg8_Smg9 DUF3584 PF12128.8 RKP01311.1 - 3 5.2 21.7 4.2 4.7 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) E1_dh PF00676.20 RKP01312.1 - 1.5e-63 214.5 0.0 2.1e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 RKP01312.1 - 8.1e-63 211.3 0.0 1.3e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RKP01312.1 - 1.3e-41 141.8 0.1 6.6e-33 113.6 0.0 3.4 3 0 0 3 3 3 3 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 RKP01312.1 - 2.1e-18 65.6 1.6 2.4e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Dynamin_N PF00350.23 RKP01313.1 - 5.1e-27 95.0 0.0 1.1e-26 93.9 0.0 1.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 RKP01313.1 - 2.8e-22 79.3 0.0 3.2e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 RKP01313.1 - 1.7e-06 28.1 0.0 4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 RKP01313.1 - 0.00036 20.6 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 RKP01313.1 - 0.17 12.3 5.1 0.45 10.9 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain CH PF00307.31 RKP01315.1 - 3.6e-19 68.9 0.0 6.2e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 RKP01315.1 - 6.1e-14 51.4 11.5 6.3e-08 32.1 3.8 2.4 2 0 0 2 2 2 2 Calponin family repeat Sigma70_ner PF04546.13 RKP01316.1 - 0.092 12.6 6.1 0.17 11.7 6.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 RKP01316.1 - 1.8 7.8 6.6 2.7 7.3 6.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RKP01316.1 - 2.7 6.1 12.0 3.8 5.6 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 RKP01316.1 - 5.9 7.3 19.0 13 6.3 19.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SelP_N PF04592.14 RKP01317.1 - 3.4 7.0 6.4 5.7 6.3 6.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNB PF00773.19 RKP01318.1 - 1.2e-101 340.3 0.0 1.7e-101 339.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 RKP01318.1 - 4.3e-21 74.7 0.0 8.8e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 RKP01318.1 - 3.3e-14 52.8 0.2 7.2e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 RKP01318.1 - 2.4e-13 50.5 0.0 6.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 RKP01318.1 - 4.8e-13 48.9 0.0 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 RKP01318.1 - 4.3e-07 30.0 0.0 3.6e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 RKP01318.1 - 1.3e-06 28.6 0.0 3.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Cas_Csy2 PF09614.10 RKP01318.1 - 0.006 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy2) RXT2_N PF08595.11 RKP01318.1 - 0.0072 16.4 1.0 0.077 13.0 0.6 2.6 2 0 0 2 2 2 1 RXT2-like, N-terminal SecD-TM1 PF13721.6 RKP01318.1 - 0.11 13.0 0.3 0.29 11.6 0.3 1.7 1 0 0 1 1 1 0 SecD export protein N-terminal TM region Sigma70_ner PF04546.13 RKP01318.1 - 0.25 11.2 5.2 0.49 10.2 5.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.6 RKP01318.1 - 0.26 11.5 5.4 0.73 10.1 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) BDHCT_assoc PF16204.5 RKP01318.1 - 2.7 7.6 8.8 5.2 6.7 8.8 1.4 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein DUF2457 PF10446.9 RKP01318.1 - 6.9 5.7 10.8 11 5.0 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 RKP01318.1 - 7.5 4.5 8.7 12 3.8 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sas10 PF09368.10 RKP01319.1 - 2.8e-14 53.4 1.5 2.8e-14 53.4 1.5 2.7 2 0 0 2 2 2 1 Sas10 C-terminal domain DnaJ PF00226.31 RKP01321.1 - 1.3e-10 41.2 0.1 2.5e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 DnaJ domain Cgr1 PF03879.14 RKP01322.1 - 8.1e-12 45.5 22.8 1.1e-11 45.0 22.8 1.2 1 0 0 1 1 1 1 Cgr1 family Efg1 PF10153.9 RKP01322.1 - 0.034 14.5 13.5 0.065 13.6 13.5 1.4 1 0 0 1 1 1 0 rRNA-processing protein Efg1 DUF4065 PF13274.6 RKP01322.1 - 0.24 12.3 0.9 0.35 11.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) DUF3464 PF11947.8 RKP01322.1 - 2.5 7.9 8.6 4.4 7.1 8.6 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MRP-L46 PF11788.8 RKP01323.1 - 3.7e-12 47.0 0.0 5.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 RKP01323.1 - 6.4e-05 23.0 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF2786 PF10979.8 RKP01323.1 - 0.031 14.2 1.1 0.031 14.2 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) TPR_2 PF07719.17 RKP01324.1 - 1.7e-19 68.3 0.6 9.2e-06 25.4 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 RKP01324.1 - 5.8e-19 67.0 0.0 2.4e-06 27.1 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RKP01324.1 - 5.7e-15 54.7 8.4 0.00097 19.8 0.0 5.9 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKP01324.1 - 2.1e-13 50.6 1.7 0.0016 18.9 0.2 4.7 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKP01324.1 - 8.7e-11 41.4 1.5 0.3 11.6 0.0 6.4 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01324.1 - 1.7e-10 41.1 5.4 0.0013 19.0 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKP01324.1 - 6.5e-10 39.5 4.0 0.00014 22.4 0.0 4.0 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 RKP01324.1 - 1e-08 34.7 0.1 0.00033 20.3 0.0 4.2 1 1 3 4 4 4 2 TPR repeat TPR_8 PF13181.6 RKP01324.1 - 6.5e-08 32.2 0.0 0.0078 16.4 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKP01324.1 - 1.7e-07 31.4 0.1 0.29 11.9 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP01324.1 - 9.8e-07 28.8 10.3 0.004 17.3 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKP01324.1 - 2.5e-05 24.0 0.6 0.17 12.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RKP01324.1 - 5.5e-05 22.8 1.3 0.00062 19.4 0.1 2.6 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 RKP01324.1 - 0.00047 19.5 0.4 2.4 7.3 0.0 3.3 2 2 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP01324.1 - 0.00055 20.1 2.8 0.23 11.7 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF4192 PF13830.6 RKP01324.1 - 0.00083 19.5 9.9 0.4 10.7 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4192) TPR_MalT PF17874.1 RKP01324.1 - 0.0021 17.5 5.5 0.39 10.0 0.1 2.6 2 1 1 3 3 3 2 MalT-like TPR region TPR_10 PF13374.6 RKP01324.1 - 0.0045 16.8 1.3 10 6.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 RKP01324.1 - 0.042 12.9 0.0 0.071 12.1 0.0 1.3 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Lipase_3 PF01764.25 RKP01325.1 - 5.6e-16 58.7 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 RKP01325.1 - 0.099 11.9 0.1 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2786 PF10979.8 RKP01325.1 - 0.29 11.1 6.1 0.82 9.6 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Complex1_LYR_2 PF13233.6 RKP01326.1 - 6.6e-07 30.0 0.6 8.1e-07 29.7 0.1 1.4 2 0 0 2 2 2 1 Complex1_LYR-like Fe-ADH PF00465.19 RKP01327.1 - 1.5e-106 356.3 0.1 1.7e-106 356.1 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 RKP01327.1 - 2.3e-14 53.7 0.1 7.1e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 RKP01327.1 - 8.6e-05 22.4 0.2 0.00013 21.7 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein WAC_Acf1_DNA_bd PF10537.9 RKP01328.1 - 2.4e-17 63.3 0.5 5.2e-17 62.2 0.5 1.6 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 RKP01328.1 - 1.5e-15 57.5 0.0 4.9e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 RKP01328.1 - 0.0015 18.8 0.6 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 DDT domain Bestrophin PF01062.21 RKP01329.1 - 6.6e-31 107.8 0.1 2e-30 106.2 0.1 1.6 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Adeno_PV PF03910.13 RKP01329.1 - 0.1 11.3 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2892 PF11127.8 RKP01329.1 - 9.7 6.3 7.4 24 5.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) Skp1 PF01466.19 RKP01330.1 - 1.9e-27 95.1 0.6 3.9e-27 94.1 0.6 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RKP01330.1 - 7.2e-22 77.3 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 RKP01330.1 - 0.0066 16.7 0.0 0.57 10.4 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain Collagen PF01391.18 RKP01331.1 - 0.013 15.2 1.9 0.013 15.2 1.9 2.1 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) CIA30 PF08547.12 RKP01331.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) OxoDH_E1alpha_N PF12573.8 RKP01331.1 - 0.2 11.4 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Dpy-30 PF05186.13 RKP01332.1 - 3e-12 46.0 0.0 4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 RKP01332.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ubiquitin PF00240.23 RKP01333.1 - 1e-15 57.2 0.0 2.7e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 RKP01333.1 - 0.00026 20.8 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RKP01333.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Blt1_C PF17183.4 RKP01333.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Get5 carboxyl domain Rad60-SLD_2 PF13881.6 RKP01333.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Afaf PF15339.6 RKP01333.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor Ubiquitin_2 PF14560.6 RKP01333.1 - 0.097 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain TMF_TATA_bd PF12325.8 RKP01334.1 - 0.1 12.8 18.6 0.1 12.8 4.1 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 RKP01334.1 - 0.16 10.9 16.8 0.36 9.6 16.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 RKP01334.1 - 0.66 10.7 1.7 15 6.3 0.1 3.1 3 0 0 3 3 3 0 Initiation control protein YabA CASP_C PF08172.12 RKP01334.1 - 3.1 7.1 16.7 0.57 9.5 7.0 3.3 2 0 0 2 2 2 0 CASP C terminal Adaptin_N PF01602.20 RKP01335.1 - 2.8e-131 438.6 4.2 3.5e-131 438.3 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKP01335.1 - 1.2e-56 191.3 1.1 5.4e-55 185.8 0.2 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP01335.1 - 7.1e-13 48.8 1.8 1.6e-07 31.6 0.5 5.3 2 2 3 5 5 5 2 HEAT repeats HEAT PF02985.22 RKP01335.1 - 4.8e-10 38.8 5.0 0.005 17.0 0.0 6.3 7 0 0 7 7 6 2 HEAT repeat Cnd3 PF12719.7 RKP01335.1 - 5.2e-05 22.6 1.0 0.0014 17.9 0.0 3.3 3 2 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain TIP120 PF08623.10 RKP01335.1 - 0.00025 20.9 5.9 0.2 11.4 0.1 2.9 3 0 0 3 3 3 2 TATA-binding protein interacting (TIP20) Arm PF00514.23 RKP01335.1 - 0.0014 18.6 0.5 0.2 11.7 0.1 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 RKP01335.1 - 0.0018 18.2 0.2 0.0018 18.2 0.2 2.6 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Atx10homo_assoc PF09759.9 RKP01335.1 - 0.01 15.9 0.3 5.8 7.0 0.0 4.0 2 1 2 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF3501 PF12007.8 RKP01335.1 - 0.011 15.8 0.5 0.39 10.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3501) Arm_2 PF04826.13 RKP01335.1 - 0.012 15.0 0.0 0.046 13.2 0.0 2.0 1 0 0 1 1 1 0 Armadillo-like RTP1_C1 PF10363.9 RKP01335.1 - 0.013 15.7 0.4 0.61 10.3 0.0 3.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 RKP01335.1 - 0.013 15.1 0.7 0.16 11.5 0.0 3.0 3 1 0 3 3 3 0 CLASP N terminal Gcn1_N PF12074.8 RKP01335.1 - 0.02 14.2 0.1 0.56 9.5 0.0 2.7 3 0 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HLH PF00010.26 RKP01336.1 - 2.9e-11 43.1 0.9 2.9e-11 43.1 0.9 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Lipase_3 PF01764.25 RKP01337.1 - 1.8e-18 66.8 0.0 3.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 RKP01337.1 - 0.00068 19.0 0.1 0.0016 17.8 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Tubulin PF00091.25 RKP01337.1 - 0.034 14.4 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Ssl1 PF04056.14 RKP01338.1 - 4.2e-65 219.2 0.0 5.5e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 RKP01338.1 - 9e-15 54.7 3.5 9e-15 54.7 3.5 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 RKP01338.1 - 6.8e-12 46.0 0.0 2e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RKP01338.1 - 0.00028 21.2 0.0 0.00059 20.1 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 RKP01338.1 - 0.066 12.7 7.4 0.1 12.0 5.4 2.2 2 1 0 2 2 2 0 Transcription factor Tfb4 IBR PF01485.21 RKP01338.1 - 3.3 8.0 13.7 29 5.0 13.7 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Abhydrolase_3 PF07859.13 RKP01339.1 - 1.1e-14 54.8 0.5 2.3e-14 53.7 0.5 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 RKP01339.1 - 1.9e-13 50.2 0.1 4.1e-13 49.1 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family adh_short_C2 PF13561.6 RKP01340.1 - 2.5e-33 115.6 0.5 2.9e-33 115.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RKP01340.1 - 7e-19 68.0 0.1 9.3e-19 67.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase SH3_4 PF06347.13 RKP01341.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial SH3 domain SHIPPO-rpt PF07004.12 RKP01342.1 - 0.001 19.9 37.8 5.8 8.0 0.1 11.0 11 0 0 11 11 11 2 Sperm-tail PG-rich repeat H-kinase_dim PF02895.14 RKP01342.1 - 0.1 13.0 2.2 0.25 11.8 2.2 1.7 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain KMP11 PF03037.16 RKP01342.1 - 0.22 12.4 0.0 0.46 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 HAUS2 PF15003.6 RKP01342.1 - 0.73 9.5 9.2 0.4 10.4 1.5 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 HD_3 PF13023.6 RKP01343.1 - 2.2e-38 131.8 0.1 2.7e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 RKP01343.1 - 4.1e-10 39.7 0.0 5.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 RKP01343.1 - 0.00024 21.3 0.1 0.00038 20.7 0.1 1.3 1 0 0 1 1 1 1 HD domain DUF3523 PF12037.8 RKP01343.1 - 0.003 17.0 0.4 0.004 16.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF3896 PF13035.6 RKP01343.1 - 0.11 12.7 0.4 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Bromo_coat PF01318.18 RKP01344.1 - 0.12 12.5 1.4 6.6 6.8 0.2 2.7 2 0 0 2 2 2 0 Bromovirus coat protein G-alpha PF00503.20 RKP01345.1 - 9.1e-121 403.3 0.0 1.1e-120 403.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RKP01345.1 - 5.7e-15 55.2 4.3 6.7e-11 41.9 0.7 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKP01345.1 - 0.0015 17.9 4.0 0.023 14.1 0.1 2.5 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RKP01345.1 - 0.0027 17.9 0.3 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 RKP01345.1 - 0.0099 15.7 0.1 0.029 14.2 0.0 1.7 2 0 0 2 2 2 1 CHC2 zinc finger AAA_29 PF13555.6 RKP01345.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RKP01345.1 - 0.062 13.4 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 RKP01345.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2875 PF11394.8 RKP01345.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) KOW PF00467.29 RKP01346.1 - 0.044 13.8 0.2 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 KOW motif PRMT5_C PF17286.2 RKP01347.1 - 2.5e-05 24.2 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PrmA PF06325.13 RKP01347.1 - 6.4e-05 22.5 0.0 9.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 RKP01347.1 - 0.0013 19.4 0.0 0.018 15.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RKP01347.1 - 0.0017 18.1 0.1 0.0025 17.5 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 RKP01347.1 - 0.0023 17.8 0.0 0.005 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKP01347.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RKP01347.1 - 0.054 14.2 0.0 0.19 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SET PF00856.28 RKP01348.1 - 3.6e-07 30.7 0.0 7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 SET domain WD40 PF00400.32 RKP01349.1 - 1e-35 121.1 24.2 1.1e-08 35.6 0.7 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01349.1 - 2.5e-08 34.1 1.9 0.04 14.2 0.2 5.8 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP01349.1 - 0.041 12.5 0.9 3.3 6.2 0.4 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKP01349.1 - 0.074 12.0 0.3 2.6 6.9 0.1 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SPX PF03105.19 RKP01350.1 - 0.0057 16.6 0.4 0.0057 16.6 0.4 2.7 1 1 1 2 2 2 1 SPX domain ATG16 PF08614.11 RKP01350.1 - 8.6 6.5 17.7 4.6 7.4 5.8 3.4 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Tim17 PF02466.19 RKP01351.1 - 0.00027 21.3 7.9 0.00044 20.6 6.5 2.0 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 RKP01351.1 - 0.18 11.4 1.4 0.81 9.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF533) HA2 PF04408.23 RKP01352.1 - 3.5e-21 75.5 0.0 3.5e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RKP01352.1 - 4.4e-18 65.4 0.0 1.7e-17 63.5 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RKP01352.1 - 2.9e-10 40.4 0.0 9.8e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKP01352.1 - 5.4e-09 36.1 0.5 9.9e-09 35.2 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RKP01352.1 - 7.1e-07 29.6 0.1 1.8e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP01352.1 - 4.3e-05 23.3 0.8 8.6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 RKP01352.1 - 7.3e-05 22.5 0.4 0.00023 20.9 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 RKP01352.1 - 0.0024 17.9 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 RKP01352.1 - 0.0069 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_7 PF12775.7 RKP01352.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region GAF PF01590.26 RKP01352.1 - 0.061 14.0 0.0 0.25 12.0 0.0 2.1 1 0 0 1 1 1 0 GAF domain AAA_23 PF13476.6 RKP01352.1 - 0.11 13.0 0.4 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain NDT80_PhoG PF05224.12 RKP01353.1 - 0.0043 17.3 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family TT_ORF2 PF02957.15 RKP01353.1 - 2.1 9.3 6.1 3.6 8.5 0.8 3.4 3 0 0 3 3 3 0 TT viral ORF2 THOC2_N PF16134.5 RKP01354.1 - 9.2e-94 315.3 0.0 2.4e-93 313.9 0.0 1.7 1 1 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 RKP01354.1 - 8.3e-49 166.4 0.0 2.4e-36 125.5 0.0 2.2 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 RKP01354.1 - 2.9e-22 78.5 0.0 5.9e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Serglycin PF04360.12 RKP01355.1 - 0.17 11.8 4.8 0.36 10.8 4.8 1.5 1 0 0 1 1 1 0 Serglycin Nop14 PF04147.12 RKP01355.1 - 4.6 5.3 14.6 8 4.5 14.6 1.3 1 0 0 1 1 1 0 Nop14-like family Thiolase_N PF00108.23 RKP01356.1 - 4.7e-82 275.2 0.6 2.3e-81 273.0 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKP01356.1 - 2.5e-45 153.1 0.7 1.7e-44 150.4 0.1 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RKP01356.1 - 1.8e-05 24.4 1.5 4.6e-05 23.1 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HSP70 PF00012.20 RKP01357.1 - 2.1e-75 254.1 0.4 1.7e-69 234.6 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 RKP01357.1 - 0.0076 15.1 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Prok_Ub PF14454.6 RKP01357.1 - 0.044 13.4 0.3 2.1 8.1 0.0 3.3 4 0 0 4 4 4 0 Prokaryotic Ubiquitin HMMR_N PF15905.5 RKP01357.1 - 0.055 12.9 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PGK PF00162.19 RKP01358.1 - 1.6e-151 504.6 0.4 1.8e-151 504.4 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Lipase_2 PF01674.18 RKP01359.1 - 2.5e-05 23.9 0.0 0.0013 18.3 0.0 2.3 2 1 0 2 2 2 2 Lipase (class 2) Abhydrolase_1 PF00561.20 RKP01359.1 - 2.8e-05 23.9 0.4 0.00025 20.8 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 RKP01359.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_6 PF12774.7 RKP01360.1 - 2.6e-146 486.8 0.0 1.6e-145 484.2 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RKP01360.1 - 7.5e-120 401.2 0.1 7.5e-120 401.2 0.1 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RKP01360.1 - 4.6e-119 398.1 1.0 4.6e-119 398.1 1.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RKP01360.1 - 1.3e-86 290.2 0.0 7.8e-85 284.3 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKP01360.1 - 6.3e-84 280.5 0.1 2.5e-83 278.5 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RKP01360.1 - 4.2e-80 269.2 0.0 1.1e-79 267.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RKP01360.1 - 3.6e-60 202.6 0.3 5.4e-53 179.2 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKP01360.1 - 1.1e-52 178.2 0.1 3.9e-52 176.4 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RKP01360.1 - 2.5e-50 171.5 10.7 4.7e-50 170.6 10.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RKP01360.1 - 3.1e-41 140.2 0.0 2.8e-40 137.1 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKP01360.1 - 1.9e-28 99.2 0.0 1.8e-11 44.2 0.0 5.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKP01360.1 - 1.1e-26 93.4 0.3 7.4e-26 90.7 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKP01360.1 - 1.1e-14 54.5 0.0 5.1e-14 52.3 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RKP01360.1 - 4.4e-10 40.0 1.1 0.13 12.5 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA PF00004.29 RKP01360.1 - 3.3e-09 37.3 0.1 0.3 11.5 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKP01360.1 - 6.7e-06 26.5 0.1 1.7 9.0 0.0 4.4 4 0 0 4 4 4 2 RNA helicase Pox_A32 PF04665.12 RKP01360.1 - 1.6e-05 24.5 0.1 0.0012 18.3 0.0 2.9 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_16 PF13191.6 RKP01360.1 - 0.0001 22.7 16.3 0.56 10.6 0.0 8.6 8 1 0 8 8 7 2 AAA ATPase domain Sigma54_activat PF00158.26 RKP01360.1 - 0.00062 19.5 0.3 0.022 14.4 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 RKP01360.1 - 0.0013 19.3 0.3 2.2 8.8 0.0 3.8 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.6 RKP01360.1 - 0.0015 18.2 1.0 7.1 6.2 0.0 4.3 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 RKP01360.1 - 0.0019 18.1 2.2 5.6 6.9 0.0 5.3 4 0 0 4 4 4 0 NACHT domain TsaE PF02367.17 RKP01360.1 - 0.0021 18.1 3.9 1.5 8.8 0.0 4.4 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RKP01360.1 - 0.0023 17.7 3.1 7.5 6.2 0.0 3.8 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 RKP01360.1 - 0.0067 16.4 2.0 14 5.5 0.0 4.1 4 0 0 4 4 3 0 Rad17 P-loop domain Mg_chelatase PF01078.21 RKP01360.1 - 0.0096 15.3 0.7 3.5 6.9 0.0 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI DnaB_bind PF10410.9 RKP01360.1 - 0.018 15.2 2.8 2.3 8.5 0.0 4.1 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase ABC_tran PF00005.27 RKP01360.1 - 0.019 15.4 5.2 4.3 7.9 0.0 4.0 4 0 0 4 4 3 0 ABC transporter AAA_29 PF13555.6 RKP01360.1 - 0.025 14.3 0.3 3.2 7.6 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RKP01360.1 - 0.032 14.1 1.1 2.4 8.0 0.1 3.5 3 0 0 3 3 3 0 RsgA GTPase IstB_IS21 PF01695.17 RKP01360.1 - 0.055 13.2 0.3 19 4.9 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 RKP01360.1 - 0.058 13.6 1.4 13 5.9 0.0 4.3 4 0 0 4 4 4 0 AAA domain CCDC14 PF15254.6 RKP01360.1 - 0.06 12.0 12.3 0.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 Roc PF08477.13 RKP01360.1 - 0.092 13.0 0.3 33 4.7 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 RKP01360.1 - 0.16 11.1 0.3 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain ATP-synt_ab PF00006.25 RKP01360.1 - 0.2 11.3 0.1 3.1 7.4 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 RKP01360.1 - 0.21 11.3 1.0 72 3.0 0.0 4.0 4 0 0 4 4 3 0 AAA domain DASH_Duo1 PF08651.10 RKP01360.1 - 5.4 6.9 6.3 17 5.3 0.2 3.8 3 0 0 3 3 2 0 DASH complex subunit Duo1 Glyco_hydro_16 PF00722.21 RKP01361.1 - 1.1e-28 99.9 0.2 1.8e-28 99.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L19e PF01280.20 RKP01362.1 - 2.7e-58 196.1 6.3 2.7e-58 196.1 6.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Sec7 PF01369.20 RKP01363.1 - 8.5e-23 81.0 0.1 1.4e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 RKP01363.1 - 3e-11 43.7 0.0 5.4e-09 36.4 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 RKP01363.1 - 0.11 13.0 0.0 0.43 11.1 0.0 1.9 2 0 0 2 2 2 0 PH domain Aconitase PF00330.20 RKP01364.1 - 5.1e-161 536.8 0.0 6.1e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RKP01364.1 - 5.4e-42 143.2 0.0 9.2e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SUR7 PF06687.12 RKP01365.1 - 5.5e-13 49.0 15.5 7.2e-13 48.7 15.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Spt20 PF12090.8 RKP01365.1 - 0.33 10.5 21.4 0.53 9.9 21.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF2207 PF09972.9 RKP01365.1 - 0.65 8.7 8.0 0.051 12.3 1.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) TFIIA PF03153.13 RKP01365.1 - 4.6 7.1 22.2 6.7 6.6 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3341 PF11821.8 RKP01365.1 - 7.8 6.1 6.0 1.2 8.7 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) PALP PF00291.25 RKP01366.1 - 6e-62 209.7 0.1 1.3e-61 208.6 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PTR2 PF00854.21 RKP01367.1 - 4.6e-74 249.6 0.1 6.9e-74 249.0 0.1 1.2 1 0 0 1 1 1 1 POT family DUF3561 PF12084.8 RKP01367.1 - 5.8 7.0 8.9 6.6 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) OAD_gamma PF04277.13 RKP01368.1 - 2.6 8.7 5.1 2.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Tyrosinase PF00264.20 RKP01369.1 - 2.8e-27 96.5 4.0 2.8e-25 89.9 4.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Lipase_GDSL_2 PF13472.6 RKP01370.1 - 7.3e-16 59.1 0.0 6.6e-14 52.7 0.0 2.7 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKP01370.1 - 1.8e-06 28.0 0.0 4e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAZAP2 PF11029.8 RKP01370.1 - 0.031 15.2 0.0 0.071 14.0 0.0 1.6 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Bap31 PF05529.12 RKP01371.1 - 1.7e-09 37.7 1.4 1e-07 31.9 0.0 2.1 2 0 0 2 2 2 2 Bap31/Bap29 transmembrane region DPM3 PF08285.11 RKP01371.1 - 0.14 12.3 0.4 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ribosomal_L38e PF01781.18 RKP01372.1 - 2.2e-28 98.1 1.1 2.5e-28 98.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family PrmA PF06325.13 RKP01373.1 - 2e-12 47.1 0.3 2.6e-12 46.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RKP01373.1 - 9.3e-10 38.3 0.2 6.2e-09 35.6 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RKP01373.1 - 1.5e-06 28.8 0.1 3.3e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RKP01373.1 - 9.1e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 RKP01373.1 - 1.6e-05 24.7 0.0 2.5e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 RKP01373.1 - 0.00068 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RKP01373.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RKP01373.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 RKP01373.1 - 0.0053 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 RKP01373.1 - 0.0081 15.9 0.1 0.024 14.3 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 RKP01373.1 - 0.052 13.1 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 RKP01373.1 - 0.097 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 RKP01373.1 - 0.15 11.4 0.2 0.27 10.5 0.2 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 RKP01373.1 - 0.18 11.7 0.1 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-LYAR PF08790.11 RKP01374.1 - 8e-14 51.2 10.0 2.3e-13 49.7 4.7 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 RKP01374.1 - 0.0018 17.8 2.2 0.42 10.3 0.4 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DM PF00751.18 RKP01374.1 - 0.19 11.7 3.3 0.35 10.8 3.3 1.4 1 0 0 1 1 1 0 DM DNA binding domain DUF4614 PF15391.6 RKP01374.1 - 0.86 9.6 10.9 0.8 9.7 9.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) Hid1 PF12722.7 RKP01374.1 - 0.98 7.5 4.4 1.1 7.3 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 RKP01374.1 - 1.4 7.5 7.4 1.8 7.2 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.15 RKP01374.1 - 3.1 6.5 8.1 3.9 6.1 8.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hydin_ADK PF17213.3 RKP01374.1 - 4.8 7.4 14.4 2.1 8.6 9.7 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Presenilin PF01080.17 RKP01374.1 - 8.3 5.1 8.1 12 4.6 8.1 1.3 1 0 0 1 1 1 0 Presenilin Sin_N PF04801.13 RKP01375.1 - 1.8e-51 175.7 0.0 2.3e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region RNA_pol_Rpb8 PF03870.15 RKP01375.1 - 0.052 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb8 zf-RING_2 PF13639.6 RKP01376.1 - 1e-10 41.8 12.1 1.8e-10 41.0 12.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RKP01376.1 - 5.1e-09 35.7 3.6 1e-08 34.7 3.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RKP01376.1 - 8.3e-07 28.8 12.5 1.5e-06 27.9 12.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP01376.1 - 9.5e-06 25.4 10.2 1.7e-05 24.6 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RKP01376.1 - 1.9e-05 24.8 10.1 4.4e-05 23.7 10.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKP01376.1 - 0.00039 20.3 8.8 0.00064 19.6 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKP01376.1 - 0.00081 19.4 9.6 0.0018 18.2 9.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RKP01376.1 - 0.0019 18.2 4.7 0.004 17.2 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RKP01376.1 - 0.0049 16.7 7.8 0.0077 16.1 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKP01376.1 - 0.034 14.0 10.7 0.065 13.1 10.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RKP01376.1 - 0.06 13.0 10.0 0.14 11.8 10.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4131 PF13567.6 RKP01376.1 - 0.53 9.9 4.3 0.47 10.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Synaptobrevin PF00957.21 RKP01377.1 - 0.55 10.1 1.5 0.94 9.3 1.5 1.3 1 0 0 1 1 1 0 Synaptobrevin Alpha_GJ PF03229.13 RKP01378.1 - 1.6 9.3 13.5 0.29 11.7 7.7 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J GN3L_Grn1 PF08701.11 RKP01380.1 - 1.4e-18 66.7 8.6 2.5e-18 65.9 8.6 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 RKP01380.1 - 3.1e-18 65.9 0.3 1.2e-14 54.4 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP01380.1 - 7.5e-09 35.3 0.5 2.1e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 RKP01380.1 - 8.2e-09 35.3 0.1 5.7e-06 26.0 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKP01380.1 - 3.3e-06 27.1 6.6 0.0081 16.1 0.1 2.9 2 1 1 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 RKP01380.1 - 0.00011 22.3 5.8 0.25 11.4 0.7 3.7 2 2 1 3 3 3 2 Dynamin family AIG1 PF04548.16 RKP01380.1 - 0.00019 20.8 2.3 0.0016 17.8 0.1 2.7 3 0 0 3 3 3 1 AIG1 family FtsK_SpoIIIE PF01580.18 RKP01380.1 - 0.0014 18.0 0.7 0.013 14.8 0.2 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.19 RKP01380.1 - 0.01 15.4 0.1 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 RKP01380.1 - 0.022 15.1 1.3 0.065 13.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 RKP01380.1 - 0.071 12.1 1.1 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RKP01380.1 - 0.1 12.8 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase UPF0242 PF06785.11 RKP01380.1 - 0.54 10.3 2.8 0.89 9.6 2.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NUDIX PF00293.28 RKP01381.1 - 0.0095 16.0 0.1 0.017 15.2 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain DNA_pol_B PF00136.21 RKP01383.1 - 1e-116 390.4 0.0 3.4e-116 388.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 RKP01383.1 - 5.9e-44 150.0 0.1 9.9e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 RKP01383.1 - 2.1e-40 138.9 0.0 4.6e-40 137.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 RKP01383.1 - 0.0032 16.4 0.0 0.0071 15.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral NblA PF04485.12 RKP01384.1 - 6.4e-05 23.3 0.9 0.00023 21.5 0.9 2.0 1 0 0 1 1 1 1 Phycobilisome degradation protein nblA Atg14 PF10186.9 RKP01384.1 - 1.2 8.2 7.7 2.2 7.3 7.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 RKP01384.1 - 3.9 7.6 20.5 0.26 11.5 7.6 3.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) 2-Hacid_dh_C PF02826.19 RKP01385.1 - 1.3e-55 187.5 0.0 2.3e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 RKP01385.1 - 5.4e-37 126.4 0.1 7.1e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 RKP01385.1 - 8.3e-07 29.3 0.2 2.6e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 RKP01385.1 - 0.00035 20.7 0.1 0.00076 19.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 RKP01385.1 - 0.0016 18.9 0.1 0.031 14.8 0.0 2.5 2 1 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 RKP01385.1 - 0.0082 15.7 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 RKP01385.1 - 0.015 15.0 0.0 0.046 13.5 0.0 1.9 1 0 0 1 1 1 0 ACT domain AlaDh_PNT_C PF01262.21 RKP01385.1 - 0.033 13.5 0.2 0.51 9.6 0.2 2.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pantoate_transf PF02548.15 RKP01385.1 - 0.095 12.1 1.6 0.15 11.4 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase BSD PF03909.17 RKP01386.1 - 1.9e-19 69.4 3.1 8.5e-13 48.1 0.4 3.3 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 RKP01386.1 - 5.2e-12 45.9 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Pheromone PF08015.11 RKP01386.1 - 9.2 7.4 8.5 0.92 10.6 1.0 3.3 3 0 0 3 3 3 0 Fungal mating-type pheromone IF4E PF01652.18 RKP01387.1 - 6.8e-47 159.2 0.0 7.7e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.18 RKP01388.1 - 2.1e-49 167.4 0.3 2.6e-49 167.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KAP PF05804.12 RKP01388.1 - 0.21 9.7 0.0 0.27 9.3 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) WD40 PF00400.32 RKP01389.1 - 8.8e-17 61.2 8.4 3.2e-05 24.6 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat NLE PF08154.12 RKP01389.1 - 1e-15 58.0 0.1 1.8e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 RKP01389.1 - 1e-06 29.0 0.0 0.23 11.8 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP01389.1 - 0.0088 14.7 1.1 0.095 11.3 0.1 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Trm112p PF03966.16 RKP01390.1 - 1.2e-16 61.0 0.0 1.7e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein DUF4639 PF15479.6 RKP01391.1 - 2.3e-05 23.6 0.0 4.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4639) UPF0449 PF15136.6 RKP01391.1 - 0.1 13.0 0.8 0.25 11.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 LIM PF00412.22 RKP01392.1 - 2.7e-07 30.7 6.1 3.9e-07 30.2 6.1 1.2 1 0 0 1 1 1 1 LIM domain SET PF00856.28 RKP01393.1 - 0.087 13.2 0.0 0.41 11.0 0.0 1.8 1 1 0 1 1 1 0 SET domain RRM_1 PF00076.22 RKP01395.1 - 3.1e-41 139.0 0.0 8.3e-19 67.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 RKP01395.1 - 9.5e-07 28.8 0.1 0.029 14.5 0.0 3.3 3 0 0 3 3 3 2 Limkain b1 RRM_occluded PF16842.5 RKP01395.1 - 3.8e-05 23.5 0.0 0.17 11.8 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RKP01395.1 - 0.0011 19.2 0.0 2.2 8.5 0.1 3.0 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RBM39linker PF15519.6 RKP01395.1 - 0.0014 19.7 0.0 0.0023 19.0 0.0 1.3 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_7 PF16367.5 RKP01395.1 - 0.0022 18.1 0.0 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RKP01395.1 - 0.01 15.8 0.0 40 4.3 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 RKP01395.1 - 0.019 14.6 0.0 1.4 8.7 0.0 2.6 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated BRAP2 PF07576.12 RKP01395.1 - 0.24 11.6 0.0 0.46 10.7 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Adaptin_N PF01602.20 RKP01396.1 - 2.8e-100 336.4 0.7 3.4e-100 336.1 0.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 RKP01396.1 - 2.1e-07 31.1 0.0 6.5e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_2 PF13646.6 RKP01396.1 - 0.013 15.9 11.5 0.59 10.6 0.3 5.5 4 2 0 5 5 5 0 HEAT repeats Cnd1 PF12717.7 RKP01396.1 - 0.016 15.2 0.3 5.7 7.0 0.2 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 RKP01396.1 - 0.026 14.6 0.8 26 5.0 0.1 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.20 RKP01396.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 RKP01396.1 - 0.17 12.3 0.5 3.8 7.9 0.0 3.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 RKP01396.1 - 0.2 12.0 7.6 4 7.9 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat Ribosomal_60s PF00428.19 RKP01396.1 - 9.2 6.9 0.0 9.2 6.9 0.0 3.9 5 0 0 5 5 5 0 60s Acidic ribosomal protein Arm PF00514.23 RKP01397.1 - 7.9e-92 298.8 12.2 3.3e-13 49.2 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 RKP01397.1 - 1.5e-23 83.0 1.1 1.6e-22 79.8 1.0 2.4 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 RKP01397.1 - 5.1e-19 68.4 0.1 2.9e-09 37.2 0.0 5.2 1 1 3 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 RKP01397.1 - 9.6e-19 67.5 5.8 1.3e-06 28.8 0.1 6.8 3 3 3 6 6 6 6 HEAT-like repeat Arm_3 PF16186.5 RKP01397.1 - 5.4e-18 64.3 0.0 1.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 RKP01397.1 - 2.6e-17 61.4 0.6 1.5e-05 24.8 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat RICTOR_V PF14668.6 RKP01397.1 - 0.00075 19.7 2.7 0.13 12.5 0.0 4.0 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 RKP01397.1 - 0.00078 19.5 0.0 0.79 9.8 0.0 4.2 3 2 3 6 6 6 2 V-ATPase subunit H HEAT_PBS PF03130.16 RKP01397.1 - 0.00085 19.8 2.4 0.73 10.7 0.0 5.1 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Arm_2 PF04826.13 RKP01397.1 - 0.0017 17.9 0.0 4.5 6.7 0.0 3.5 2 1 2 4 4 4 2 Armadillo-like Atx10homo_assoc PF09759.9 RKP01397.1 - 0.012 15.7 0.4 0.71 9.9 0.0 3.3 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 RKP01397.1 - 0.017 15.2 0.0 7.9 6.5 0.0 3.3 1 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 FmrO PF07091.11 RKP01397.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) G6PD_C PF02781.16 RKP01398.1 - 5.7e-117 390.0 0.0 7.6e-117 389.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RKP01398.1 - 1.2e-60 205.1 0.3 1.8e-60 204.6 0.3 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain NuiA PF07924.11 RKP01398.1 - 0.13 12.7 0.1 1.5 9.2 0.1 2.2 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Lipase_GDSL_2 PF13472.6 RKP01399.1 - 3.6e-12 47.1 0.3 2.3e-11 44.4 0.0 2.4 2 1 1 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKP01399.1 - 0.00043 20.3 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HSP20 PF00011.21 RKP01400.1 - 5.8e-09 36.0 0.0 3e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 RKP01400.1 - 0.0041 18.1 0.0 0.0059 17.6 0.0 1.3 1 1 0 1 1 1 1 CS domain FA_hydroxylase PF04116.13 RKP01401.1 - 3e-26 92.3 15.3 3.9e-26 92.0 11.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EF-hand_1 PF00036.32 RKP01402.1 - 4e-23 79.2 8.3 8.5e-07 28.1 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKP01402.1 - 1.5e-22 79.8 8.5 4e-13 49.6 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RKP01402.1 - 8.3e-22 75.2 3.1 5.5e-06 25.9 0.0 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RKP01402.1 - 6e-16 57.1 5.0 6.6e-05 22.2 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RKP01402.1 - 3.1e-12 46.1 6.6 1.2e-05 25.0 0.6 4.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 RKP01402.1 - 1.1e-06 28.5 6.1 0.42 10.6 0.3 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RKP01402.1 - 0.0019 18.5 2.7 1.1 9.5 0.5 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1707 PF08044.11 RKP01402.1 - 0.057 13.5 0.1 7.9 6.6 0.0 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF1707) EF-hand_9 PF14658.6 RKP01402.1 - 0.11 12.9 0.6 1.5 9.2 0.0 2.8 3 1 0 3 3 3 0 EF-hand domain Pan3_PK PF18101.1 RKP01402.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain RRM_1 PF00076.22 RKP01403.1 - 1.9e-22 78.8 0.0 6.4e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEC-1_N PF04625.13 RKP01404.1 - 2.1 7.3 16.3 3.5 6.6 16.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Mito_carr PF00153.27 RKP01405.1 - 3.6e-31 106.9 6.7 4.9e-14 52.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RKP01405.1 - 0.012 14.8 0.6 0.026 13.7 0.3 1.8 1 1 1 2 2 2 0 Gammaproteobacterial serine protease WD40 PF00400.32 RKP01406.1 - 0.24 12.4 8.0 3.7 8.6 0.1 4.6 4 2 1 5 5 5 0 WD domain, G-beta repeat Peptidase_C50 PF03568.17 RKP01407.1 - 9e-87 291.8 0.0 1.4e-86 291.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 DUF4050 PF13259.6 RKP01407.1 - 0.26 11.6 2.8 1 9.7 2.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Alg6_Alg8 PF03155.15 RKP01408.1 - 3.2e-105 352.9 20.3 4e-105 352.6 20.3 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family NAD_binding_1 PF00175.21 RKP01409.1 - 2.5e-22 79.6 0.0 3.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RKP01409.1 - 9.8e-11 41.9 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RKP01409.1 - 0.015 15.4 0.0 0.061 13.5 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain TPR_1 PF00515.28 RKP01410.1 - 9.8e-57 186.6 28.3 6.7e-08 32.0 0.0 11.5 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 RKP01410.1 - 1.2e-48 159.3 29.0 2.1e-05 24.3 2.6 10.7 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 RKP01410.1 - 3.9e-37 123.3 22.4 0.00016 21.6 1.2 11.1 10 2 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 RKP01410.1 - 1.1e-30 103.8 20.0 6.6e-05 23.0 0.1 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 RKP01410.1 - 7.9e-28 94.8 16.4 0.002 18.8 0.0 9.6 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 RKP01410.1 - 1.1e-24 86.8 22.1 2e-06 28.3 0.0 7.2 4 1 5 9 9 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 RKP01410.1 - 3e-24 85.3 19.1 4.7e-06 27.0 0.3 7.0 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01410.1 - 3.9e-23 81.5 30.1 1.8e-05 24.9 1.6 8.2 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 RKP01410.1 - 2.1e-22 78.5 33.5 9.3e-06 25.2 0.7 10.2 4 3 6 10 10 10 6 TPR repeat TPR_9 PF13371.6 RKP01410.1 - 5.8e-22 77.6 17.6 0.0013 18.8 0.5 6.6 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 RKP01410.1 - 3.6e-20 71.2 21.7 0.042 14.5 0.1 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 RKP01410.1 - 1.3e-18 65.5 20.2 0.00074 19.4 0.1 9.8 10 1 0 10 10 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP01410.1 - 8.6e-12 45.1 10.8 8.8e-07 29.1 1.6 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RKP01410.1 - 2.7e-11 43.2 11.1 0.025 13.8 0.0 5.7 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_20 PF14561.6 RKP01410.1 - 5.7e-07 29.8 4.2 0.012 15.9 0.3 5.1 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 RKP01410.1 - 7.8e-06 25.7 14.2 0.013 15.2 2.4 5.0 3 1 1 5 5 5 2 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 RKP01410.1 - 0.00047 19.9 8.2 0.024 14.4 0.2 3.6 2 2 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) Rapsyn_N PF10579.9 RKP01410.1 - 0.027 14.6 1.7 14 5.8 0.1 4.4 3 3 2 5 5 5 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.6 RKP01410.1 - 0.034 14.0 25.9 2.3 8.2 0.1 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat SNAP PF14938.6 RKP01410.1 - 0.044 13.2 16.6 0.31 10.4 0.6 4.8 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP DUF1380 PF07128.12 RKP01410.1 - 0.13 12.5 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) Fis1_TPR_C PF14853.6 RKP01410.1 - 0.57 10.3 9.1 9.3 6.4 0.0 6.0 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 RKP01410.1 - 0.69 10.0 26.2 1.8 8.6 1.7 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1965 PF09248.10 RKP01410.1 - 0.95 9.3 8.3 26 4.7 0.1 4.8 3 1 2 5 5 5 0 Domain of unknown function (DUF1965) BTAD PF03704.17 RKP01410.1 - 1.6 9.2 11.8 29 5.1 0.9 3.7 2 2 0 3 3 3 0 Bacterial transcriptional activator domain Tuberin PF03542.16 RKP01411.1 - 3e-34 118.7 3.1 4.9e-34 118.0 3.1 1.3 1 0 0 1 1 1 1 Tuberin Rap_GAP PF02145.15 RKP01411.1 - 5.1e-31 107.7 0.0 8.4e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP DUF1751 PF08551.10 RKP01412.1 - 2.9e-18 66.3 0.3 6.2e-18 65.2 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 RKP01412.1 - 0.00072 19.6 5.9 0.0013 18.7 5.9 1.4 1 0 0 1 1 1 1 Rhomboid family PPP4R2 PF09184.11 RKP01413.1 - 4.6e-13 49.4 0.0 1.3e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 PPP4R2 CAP_N PF01213.19 RKP01413.1 - 0.34 10.4 5.5 0.47 9.9 1.5 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF5558 PF17713.1 RKP01413.1 - 7.8 6.9 9.8 3.8 7.9 3.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5558) Nfu_N PF08712.11 RKP01414.1 - 1e-28 99.2 0.0 2.4e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 RKP01414.1 - 6.5e-28 96.7 0.2 1.1e-27 96.0 0.2 1.3 1 0 0 1 1 1 1 NifU-like domain CtaG_Cox11 PF04442.14 RKP01415.1 - 1.4e-58 197.2 0.3 1.7e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF3953 PF13129.6 RKP01415.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) TPR_19 PF14559.6 RKP01416.1 - 1.9e-09 37.9 24.4 0.006 17.1 1.1 7.2 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 RKP01416.1 - 0.00037 20.6 2.1 0.00037 20.6 2.1 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKP01416.1 - 0.0037 16.9 1.5 11 5.8 0.1 4.1 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 RKP01416.1 - 0.0099 15.9 0.9 7.6 6.9 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP01416.1 - 0.019 15.0 0.8 5 7.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKP01416.1 - 0.088 13.2 0.0 38 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NmrA PF05368.13 RKP01417.1 - 1e-12 48.1 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 RKP01417.1 - 3.4e-06 27.1 0.0 6.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 RKP01417.1 - 0.0024 17.4 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HTH_17 PF12728.7 RKP01417.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Tcp11 PF05794.13 RKP01418.1 - 7.1e-17 61.6 0.0 8.3e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Ribonuc_red_lgC PF02867.15 RKP01419.1 - 5.5e-181 602.6 0.0 7.8e-181 602.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 RKP01419.1 - 3.3e-24 84.7 0.1 7.2e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 RKP01419.1 - 3.2e-17 62.9 0.0 1e-16 61.3 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain Porin_3 PF01459.22 RKP01420.1 - 9.4e-52 176.1 1.3 1.1e-51 175.9 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin POT1PC PF16686.5 RKP01421.1 - 2.9e-08 33.7 0.1 0.0011 18.8 0.0 3.3 2 1 0 2 2 2 2 ssDNA-binding domain of telomere protection protein IBN_N PF03810.19 RKP01422.1 - 4.3e-19 68.2 0.1 1.9e-17 63.0 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 RKP01422.1 - 3e-05 23.0 0.0 0.0001 21.3 0.0 1.9 2 0 0 2 2 2 1 Cse1 RRN3 PF05327.11 RKP01422.1 - 0.00082 18.0 5.7 0.28 9.7 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 Y_phosphatase PF00102.27 RKP01423.1 - 2e-61 207.6 0.0 2.3e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RKP01423.1 - 0.0018 18.3 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RKP01423.1 - 0.0066 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RKP01423.1 - 0.083 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Transglut_core PF01841.19 RKP01424.1 - 0.00039 20.8 0.5 0.0036 17.8 0.5 2.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily Slu7 PF11708.8 RKP01424.1 - 3.8 7.2 6.4 1 9.0 0.4 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor COX17 PF05051.13 RKP01425.1 - 5e-20 71.6 9.4 5.6e-20 71.4 9.4 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_L17 PF01196.19 RKP01426.1 - 1.4e-19 70.7 0.1 2.9e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 DUF5566 PF17721.1 RKP01427.1 - 0.053 13.8 0.4 0.076 13.3 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Ank_2 PF12796.7 RKP01428.1 - 7.4e-26 90.6 3.3 5.8e-15 55.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKP01428.1 - 2e-23 82.5 2.8 1.5e-11 44.6 0.4 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RKP01428.1 - 3e-21 75.2 5.7 3e-10 40.1 1.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RKP01428.1 - 2.3e-18 65.7 6.8 9.8e-07 29.0 0.2 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RKP01428.1 - 2.6e-16 58.0 2.6 9e-06 25.7 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Dus PF01207.17 RKP01429.1 - 7.1e-71 238.8 0.1 8.7e-71 238.5 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 RKP01429.1 - 0.054 12.7 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 RKP01429.1 - 0.094 12.1 0.3 0.33 10.3 0.2 1.8 1 1 1 2 2 2 0 Nitronate monooxygenase tRNA_bind PF01588.20 RKP01431.1 - 2.3e-28 98.1 0.1 3e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain FAA_hydrolase PF01557.18 RKP01432.1 - 2.5e-44 151.5 0.1 4.2e-44 150.8 0.1 1.3 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 RKP01434.1 - 2.2e-18 66.9 0.1 1.2e-17 64.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 RKP01434.1 - 2.7e-17 62.1 0.0 6.5e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 RKP01434.1 - 0.00013 21.3 0.0 0.0043 16.3 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 RKP01434.1 - 0.16 11.6 0.0 0.63 9.7 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Fe_hyd_lg_C PF02906.14 RKP01435.1 - 9.2e-60 202.3 0.0 2.4e-59 201.0 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HEM4 PF02602.15 RKP01435.1 - 0.052 12.9 0.3 0.099 12.0 0.0 1.5 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Chitin_synth_2 PF03142.15 RKP01436.1 - 2.6e-210 699.6 0.0 2.6e-210 699.6 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 RKP01436.1 - 7.8e-12 45.5 7.5 7.8e-12 45.5 7.5 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKP01436.1 - 1.1e-10 41.9 0.0 4.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RKP01436.1 - 2.4e-07 30.4 0.0 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 RKP01436.1 - 0.00045 20.1 0.0 0.0094 15.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.28 RKP01436.1 - 0.017 15.3 0.0 0.93 9.7 0.0 3.0 2 1 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain DUF3149 PF11346.8 RKP01436.1 - 0.76 9.4 6.4 3.2 7.5 6.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Sec1 PF00995.23 RKP01437.1 - 1.9e-113 380.7 0.0 2.2e-113 380.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCHC_2 PF13696.6 RKP01439.1 - 1.5e-35 120.5 48.8 6.7e-10 38.6 8.1 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC PF00098.23 RKP01439.1 - 3.1e-17 61.8 33.2 8.2e-05 22.5 2.4 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 RKP01439.1 - 8.9e-08 32.0 15.1 0.063 13.3 0.1 4.9 5 0 0 5 5 5 4 Zinc knuckle eIF3g PF12353.8 RKP01439.1 - 1.1e-06 29.1 23.2 0.94 9.9 0.3 5.1 4 1 1 5 5 5 4 Eukaryotic translation initiation factor 3 subunit G Zn_ribbon_SprT PF17283.2 RKP01439.1 - 0.013 15.4 18.6 9.4 6.2 0.0 5.6 5 1 1 6 6 6 0 SprT-like zinc ribbon domain zf-CCHC_5 PF14787.6 RKP01439.1 - 0.073 12.8 28.8 1.3 8.8 1.8 4.6 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger PHD PF00628.29 RKP01439.1 - 0.29 11.1 17.0 13 5.8 0.2 4.6 3 1 2 5 5 5 0 PHD-finger zf-CCHC_4 PF14392.6 RKP01439.1 - 0.35 10.6 26.5 0.69 9.7 0.4 5.1 5 0 0 5 5 5 0 Zinc knuckle zf-C2H2_10 PF16588.5 RKP01439.1 - 0.41 10.4 26.3 0.073 12.8 1.7 4.5 4 0 0 4 4 4 0 C2H2 zinc-finger YXWGXW PF12779.7 RKP01439.1 - 2.1 8.6 9.4 36 4.6 0.5 3.7 3 0 0 3 3 3 0 YXWGXW repeat (2 copies) zinc-ribbons_6 PF07191.12 RKP01439.1 - 2.4 8.2 18.8 53 3.9 3.0 4.3 1 1 4 5 5 5 0 zinc-ribbons zf-CHY PF05495.12 RKP01439.1 - 2.9 8.4 15.3 1.6 9.3 2.6 3.6 2 1 1 3 3 3 0 CHY zinc finger Herpes_capsid PF06112.11 RKP01439.1 - 2.9 7.9 11.7 2 8.5 5.3 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Cytochrome_C7 PF14522.6 RKP01439.1 - 6.8 6.8 11.6 1.9 8.5 0.4 3.0 2 1 1 3 3 3 0 Cytochrome c7 and related cytochrome c WD40 PF00400.32 RKP01440.1 - 0.001 19.8 0.1 1.3 10.0 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Glyco_hydro_61 PF03443.14 RKP01441.1 - 4.4e-48 163.9 0.0 5.4e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PDZ_6 PF17820.1 RKP01442.1 - 0.049 13.5 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 PDZ domain Caveolin PF01146.17 RKP01442.1 - 0.099 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Caveolin Histone PF00125.24 RKP01444.1 - 5.3e-38 130.3 0.3 6.8e-38 130.0 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKP01444.1 - 0.0025 18.1 0.0 0.035 14.4 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 RKP01444.1 - 0.0033 17.5 0.1 0.005 17.0 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 RKP01444.1 - 0.015 15.7 0.1 0.026 14.9 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein TPR_2 PF07719.17 RKP01445.1 - 1.6e-08 34.0 8.2 0.0011 18.9 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP01445.1 - 0.0013 18.4 3.4 0.042 13.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKP01445.1 - 0.0014 18.3 0.6 0.23 11.2 0.3 2.5 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 RKP01445.1 - 0.0029 17.7 18.6 0.032 14.4 4.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP01445.1 - 0.0049 17.0 1.6 0.18 12.1 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF630 PF04783.12 RKP01445.1 - 0.1 12.8 0.1 0.1 12.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF630) TPR_6 PF13174.6 RKP01445.1 - 0.1 13.3 0.5 0.1 13.3 0.5 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF3245 PF11595.8 RKP01445.1 - 0.1 13.0 1.9 0.21 12.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) TPR_7 PF13176.6 RKP01445.1 - 0.15 12.1 2.4 0.93 9.7 0.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 RKP01445.1 - 0.27 11.9 32.3 0.074 13.7 9.0 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP01445.1 - 1.7 8.7 10.3 1.6 8.7 2.9 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.26 RKP01446.1 - 2.1e-28 99.1 0.0 2.5e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Thymidylate_kin PF02223.17 RKP01447.1 - 1.4e-40 138.9 0.0 1.6e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 RKP01447.1 - 0.00037 20.8 0.0 0.00055 20.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 RKP01447.1 - 0.0055 16.6 0.0 0.007 16.2 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 RKP01447.1 - 0.014 15.7 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 RKP01447.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase DUF1887 PF09002.11 RKP01447.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) KTI12 PF08433.10 RKP01447.1 - 0.21 11.0 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TPT PF03151.16 RKP01448.1 - 5.5e-57 193.3 14.3 6.5e-57 193.1 14.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 RKP01448.1 - 1.6e-12 47.8 30.3 2.8e-06 27.5 9.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 RKP01448.1 - 0.86 9.7 8.9 0.16 12.0 2.7 2.4 2 1 0 2 2 2 0 Putative transmembrane family 234 CybS PF05328.12 RKP01449.1 - 2.3e-29 101.7 0.1 2.5e-29 101.6 0.1 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cyclin PF08613.11 RKP01450.1 - 2.5e-11 44.2 0.4 8e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Cyclin UBA PF00627.31 RKP01451.1 - 1.3e-09 37.8 1.3 1.4e-05 24.9 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain DUF4770 PF15994.5 RKP01451.1 - 0.14 12.4 11.1 0.11 12.7 9.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) IATP PF04568.12 RKP01451.1 - 0.56 10.7 8.5 0.28 11.6 1.8 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Presenilin PF01080.17 RKP01451.1 - 1.9 7.1 3.1 3 6.5 3.1 1.3 1 0 0 1 1 1 0 Presenilin RhoGAP PF00620.27 RKP01452.1 - 7.1e-30 103.8 0.1 8.5e-30 103.6 0.1 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF3336 PF11815.8 RKP01454.1 - 3.1e-34 117.7 1.4 5.8e-34 116.8 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RKP01454.1 - 8.1e-22 78.4 0.0 1.7e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Aldo_ket_red PF00248.21 RKP01455.1 - 1.1e-12 47.8 0.0 8.1e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Aldo/keto reductase family Foie-gras_1 PF11817.8 RKP01455.1 - 0.03 13.9 0.2 0.054 13.1 0.2 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 HTH_30 PF13556.6 RKP01455.1 - 0.4 10.5 5.6 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain TRM PF02005.16 RKP01457.1 - 2.8e-120 401.9 0.0 3.3e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 RKP01457.1 - 0.00082 19.2 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RKP01457.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 RKP01457.1 - 0.047 13.2 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 RKP01457.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PPK2 PF03976.14 RKP01457.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) PrmA PF06325.13 RKP01457.1 - 0.22 10.9 0.2 0.34 10.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCI PF01399.27 RKP01458.1 - 1.6e-21 76.7 0.6 4.1e-21 75.5 0.6 1.7 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 RKP01458.1 - 0.0033 17.4 0.1 0.008 16.2 0.1 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RPN6_N PF18055.1 RKP01458.1 - 0.38 11.1 2.7 5.5 7.4 0.1 3.5 3 1 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain RF-1 PF00472.20 RKP01459.1 - 4.6e-12 45.9 0.0 5.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain RasGAP PF00616.19 RKP01460.1 - 1.5e-25 90.1 0.0 5.1e-24 85.2 0.0 2.4 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 RKP01460.1 - 9.4e-12 45.1 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain PH PF00169.29 RKP01460.1 - 3e-10 40.5 0.0 5.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 PH domain FCH PF00611.23 RKP01460.1 - 0.011 16.0 0.9 0.011 16.0 0.9 2.7 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Plexin_cytopl PF08337.12 RKP01460.1 - 0.021 13.5 0.1 1.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF3384 PF11864.8 RKP01460.1 - 0.1 11.5 3.3 0.15 10.9 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3384) MCU PF04678.13 RKP01461.1 - 1.7e-18 67.3 0.0 2.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter XPG_I PF00867.18 RKP01463.1 - 7.4e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RKP01463.1 - 0.00014 22.3 0.0 0.00043 20.7 0.0 1.9 1 1 0 1 1 1 1 XPG N-terminal domain TFIID-31kDa PF02291.15 RKP01463.1 - 0.11 12.6 0.4 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Atx10homo_assoc PF09759.9 RKP01464.1 - 0.05 13.6 0.0 0.32 11.0 0.0 2.4 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain XPG_N PF00752.17 RKP01465.1 - 2e-33 114.8 0.0 2.7e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain DUF5365 PF17326.2 RKP01465.1 - 0.026 14.9 0.0 0.032 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) XPG_I PF00867.18 RKP01466.1 - 3.6e-25 88.2 0.0 5.3e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 RKP01466.1 - 0.0044 16.5 0.0 0.045 13.2 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing BCA_ABC_TP_C PF12399.8 RKP01466.1 - 0.088 12.8 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter 5_3_exonuc PF01367.20 RKP01466.1 - 0.18 12.4 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Paf1 PF03985.13 RKP01467.1 - 9.5e-27 94.1 0.0 2.2e-26 92.9 0.0 1.5 1 1 0 1 1 1 1 Paf1 Peptidase_M20 PF01546.28 RKP01468.1 - 7e-35 120.6 0.1 8.9e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RKP01468.1 - 8.4e-14 51.4 0.0 1.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Rep_fac-A_3 PF08661.11 RKP01469.1 - 3.1e-22 78.9 0.0 3.4e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 ALO PF04030.14 RKP01470.1 - 1.9e-62 211.5 0.0 2.3e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 RKP01470.1 - 1.8e-22 79.6 1.2 2.8e-22 79.0 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 RKP01470.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like DUF1168 PF06658.12 RKP01472.1 - 9.9e-24 83.7 5.1 1.6e-23 83.0 5.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) CobT_C PF11775.8 RKP01472.1 - 0.24 11.0 2.4 0.35 10.5 2.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Yip1 PF04893.17 RKP01473.1 - 9e-16 58.1 13.7 4.3e-15 55.9 13.9 1.8 1 1 0 1 1 1 1 Yip1 domain DUF5325 PF17259.2 RKP01473.1 - 0.94 9.4 6.7 3 7.8 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) RasGEF PF00617.19 RKP01474.1 - 1.8e-46 158.6 0.4 4.1e-46 157.4 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain Ank_2 PF12796.7 RKP01474.1 - 1.6e-07 31.8 1.1 3.5e-07 30.7 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKP01474.1 - 3.1e-07 30.8 0.2 6.7e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RKP01474.1 - 1.8e-05 25.0 3.0 0.03 14.8 0.5 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 RKP01474.1 - 3.2e-05 24.0 0.3 0.18 12.5 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 RKP01474.1 - 7.1e-05 23.0 0.5 0.0033 17.7 0.3 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) M_domain PF12938.7 RKP01474.1 - 0.00028 20.8 3.5 0.0027 17.6 0.1 2.4 2 0 0 2 2 2 1 M domain of GW182 RasGEF_N PF00618.20 RKP01474.1 - 0.019 15.2 0.0 0.077 13.2 0.0 2.0 2 0 0 2 2 2 0 RasGEF N-terminal motif IlvC PF01450.19 RKP01474.1 - 0.064 13.5 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Swi5 PF07061.11 RKP01474.1 - 1 9.5 7.3 3.9 7.6 0.1 3.7 3 1 0 3 3 3 0 Swi5 Lzipper-MIP1 PF14389.6 RKP01474.1 - 3.3 8.1 8.4 1.2 9.5 0.1 3.8 4 0 0 4 4 3 0 Leucine-zipper of ternary complex factor MIP1 MCC-bdg_PDZ PF10506.9 RKP01474.1 - 4.5 7.4 7.1 1.4 8.9 0.2 3.0 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Snf7 PF03357.21 RKP01474.1 - 6.6 6.3 11.7 3.5 7.2 3.0 3.1 3 0 0 3 3 3 0 Snf7 FlxA PF14282.6 RKP01474.1 - 9.4 6.3 11.0 0.6 10.1 1.7 2.5 2 0 0 2 2 2 0 FlxA-like protein Ada3 PF10198.9 RKP01475.1 - 5e-23 81.7 0.7 5e-23 81.7 0.7 2.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 SUIM_assoc PF16619.5 RKP01475.1 - 0.0049 16.9 1.9 0.0049 16.9 1.9 2.0 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 RKP01475.1 - 0.18 11.4 6.9 0.35 10.4 6.9 1.4 1 0 0 1 1 1 0 Spt20 family Sel1 PF08238.12 RKP01476.1 - 1.3e-05 25.6 2.9 1.9 9.3 0.2 4.2 4 0 0 4 4 4 3 Sel1 repeat Metallophos PF00149.28 RKP01477.1 - 4.1e-08 34.0 0.0 6.5e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Zip PF02535.22 RKP01478.1 - 5.8e-18 65.2 18.7 6.3e-12 45.4 7.2 3.3 2 1 0 3 3 3 2 ZIP Zinc transporter E1-E2_ATPase PF00122.20 RKP01478.1 - 0.7 9.4 5.6 0.075 12.5 0.6 2.0 2 1 0 2 2 2 0 E1-E2 ATPase GTP_EFTU PF00009.27 RKP01479.1 - 7.8e-59 198.5 0.0 1.7e-58 197.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 RKP01479.1 - 8.6e-26 89.8 0.0 2e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RKP01479.1 - 3.9e-13 49.2 0.0 1e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKP01479.1 - 1.9e-05 25.0 0.0 4.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RKP01479.1 - 2.6e-05 24.1 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 RKP01479.1 - 0.0005 20.1 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 RKP01479.1 - 0.0035 17.1 0.0 0.035 13.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G, domain IV AIG1 PF04548.16 RKP01479.1 - 0.22 10.8 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family LIM PF00412.22 RKP01480.1 - 3.2e-07 30.5 0.3 3.2e-07 30.5 0.3 2.2 3 0 0 3 3 3 1 LIM domain MLVIN_C PF18697.1 RKP01482.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Ras PF00071.22 RKP01483.1 - 1.2e-17 64.0 0.0 1.8e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RKP01483.1 - 1.5e-10 41.4 0.0 3.5e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RKP01483.1 - 0.032 14.2 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 RKP01483.1 - 0.069 13.5 0.2 0.1 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 RKP01483.1 - 0.089 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 RKP01483.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RKP01483.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 RKP01484.1 - 6.6e-08 32.2 0.0 0.0038 16.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Nop14 PF04147.12 RKP01484.1 - 1.4 7.1 15.2 0.0094 14.2 6.3 1.7 2 0 0 2 2 2 0 Nop14-like family DEAD PF00270.29 RKP01486.1 - 1.4e-20 73.7 0.0 5.8e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01486.1 - 5.7e-19 68.5 0.0 1.2e-16 61.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP01486.1 - 4.2e-08 33.4 0.0 9.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 RKP01486.1 - 9.7e-06 25.1 0.2 2.2e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD RecQ_Zn_bind PF16124.5 RKP01486.1 - 0.0014 19.3 0.0 0.0052 17.5 0.0 2.0 1 0 0 1 1 1 1 RecQ zinc-binding AAA_22 PF13401.6 RKP01486.1 - 0.002 18.4 0.0 0.011 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain MEDS PF14417.6 RKP01486.1 - 0.0085 15.9 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AP_endonuc_2 PF01261.24 RKP01486.1 - 0.028 13.9 0.6 0.045 13.2 0.6 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel SelB-wing_1 PF09105.10 RKP01486.1 - 0.087 12.8 0.4 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 Elongation factor SelB, winged helix ADH_N PF08240.12 RKP01487.1 - 8.2e-25 86.8 3.2 8.2e-25 86.8 3.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKP01487.1 - 1.2e-17 64.1 0.0 2.6e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RKP01487.1 - 2.5e-08 33.7 0.0 5.2e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RKP01487.1 - 5.3e-08 34.0 0.0 1.1e-07 33.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 RKP01487.1 - 0.00044 19.6 0.1 0.00073 18.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 RKP01487.1 - 0.00076 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 RKP01487.1 - 0.0032 18.0 0.0 0.0085 16.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RKP01487.1 - 0.018 15.5 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RKP01487.1 - 0.029 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RKP01487.1 - 0.038 12.7 0.1 0.062 12.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_11 PF08241.12 RKP01487.1 - 0.04 14.6 0.1 0.11 13.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 RKP01487.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 RKP01487.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hydrophobin PF01185.18 RKP01488.1 - 8.8e-06 26.3 5.5 1.5e-05 25.6 5.5 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Med3 PF11593.8 RKP01488.1 - 2.2 7.4 7.5 2.8 7.0 7.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hydrophobin PF01185.18 RKP01489.1 - 3e-08 34.2 10.8 4.4e-08 33.6 10.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Ank_5 PF13857.6 RKP01490.1 - 2e-13 50.3 2.6 3.9e-11 43.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKP01490.1 - 2.5e-13 50.4 0.0 4.5e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKP01490.1 - 1e-11 43.9 0.5 1.8e-07 30.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RKP01490.1 - 2.6e-11 43.8 0.5 2.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RKP01490.1 - 7e-10 38.9 2.0 1.6e-07 31.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat CTP_transf_like PF01467.26 RKP01491.1 - 1.1e-27 97.0 0.0 1.7e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like EnY2 PF10163.9 RKP01491.1 - 0.057 13.8 1.2 1.6 9.2 1.2 2.5 1 1 0 1 1 1 0 Transcription factor e(y)2 SNARE_assoc PF09335.11 RKP01492.1 - 3e-17 63.2 5.3 6.7e-17 62.1 5.3 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Actin PF00022.19 RKP01493.1 - 1.9e-25 89.4 0.0 4e-17 61.9 0.0 3.0 2 1 0 2 2 2 2 Actin FtsA PF14450.6 RKP01493.1 - 0.037 14.5 0.0 0.058 13.8 0.0 1.6 1 1 0 1 1 1 0 Cell division protein FtsA Actin_micro PF17003.5 RKP01493.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative actin-like family Glyoxal_oxid_N PF07250.11 RKP01494.1 - 4.5e-25 88.2 0.0 2.1e-24 86.1 0.0 2.1 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 RKP01494.1 - 2.6e-18 66.1 0.0 8.5e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) FAM117 PF15388.6 RKP01494.1 - 0.00081 18.9 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein Family FAM117 DUF3323 PF11796.8 RKP01494.1 - 0.098 12.5 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) AMP-binding PF00501.28 RKP01495.1 - 2.1e-29 102.4 6.4 3.2e-10 39.2 0.0 5.0 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 RKP01495.1 - 0.00018 22.3 0.0 0.00071 20.4 0.0 2.1 1 0 0 1 1 1 1 DMAP1-binding Domain Rrp40_N PF18311.1 RKP01496.1 - 4.1e-05 23.4 0.0 9.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 RKP01496.1 - 0.00017 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 KH domain IPPT PF01715.17 RKP01497.1 - 3.5e-59 200.4 0.0 4.4e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 RKP01497.1 - 0.0011 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 RKP01497.1 - 0.0015 18.7 0.2 0.005 17.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RKP01497.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein baeRF_family3 PF18845.1 RKP01497.1 - 0.019 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 AAA_16 PF13191.6 RKP01497.1 - 0.023 15.1 0.1 0.051 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 RKP01497.1 - 0.031 14.4 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 RKP01497.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 RKP01497.1 - 0.056 13.7 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RKP01497.1 - 0.056 14.0 0.0 0.098 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 RKP01497.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA PF00004.29 RKP01497.1 - 0.18 12.2 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 RKP01497.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SART-1 PF03343.13 RKP01498.1 - 2.4e-75 254.4 7.0 4e-75 253.6 7.0 1.3 1 0 0 1 1 1 1 SART-1 family RhoGAP PF00620.27 RKP01499.1 - 5.6e-24 84.7 0.0 9.4e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 RKP01499.1 - 2.8e-17 63.2 0.0 5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 RKP01499.1 - 0.00023 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain BIR PF00653.21 RKP01500.1 - 2.1e-07 31.5 0.1 0.0086 16.7 0.0 3.0 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Clat_adaptor_s PF01217.20 RKP01501.1 - 0.00016 21.7 0.0 0.00049 20.0 0.0 1.8 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Ribonuclease_3 PF00636.26 RKP01502.1 - 4.2e-28 98.0 0.0 4.7e-14 52.9 0.0 3.6 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 RKP01502.1 - 1.2e-18 67.5 0.0 2e-10 40.9 0.0 2.7 2 1 0 2 2 2 2 Ribonuclease-III-like RWD PF05773.22 RKP01503.1 - 6.4e-16 58.7 0.0 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 RKP01503.1 - 1.2e-06 28.9 5.2 2.4e-06 28.0 5.2 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Fcf2 PF08698.11 RKP01505.1 - 6.4e-17 61.7 0.0 7.1e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing FH2 PF02181.23 RKP01507.1 - 8.9e-93 311.4 1.4 8.9e-93 311.4 1.4 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RKP01507.1 - 1.2e-39 136.0 0.1 2.9e-39 134.7 0.0 1.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RKP01507.1 - 8e-37 126.6 0.0 4.7e-36 124.1 0.0 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain adh_short PF00106.25 RKP01508.1 - 4.7e-28 98.0 0.1 6.6e-28 97.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKP01508.1 - 3.1e-27 95.7 1.7 4.3e-27 95.2 1.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKP01508.1 - 0.00024 21.0 0.2 0.00037 20.5 0.2 1.2 1 0 0 1 1 1 1 KR domain GATase PF00117.28 RKP01509.1 - 1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKP01509.1 - 0.00014 21.7 0.2 0.0017 18.1 0.2 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 RKP01509.1 - 0.023 14.5 0.0 0.067 13.0 0.0 1.6 2 0 0 2 2 2 0 DJ-1/PfpI family GATase_3 PF07685.14 RKP01509.1 - 0.21 11.2 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF1664 PF07889.12 RKP01510.1 - 0.26 11.3 0.1 0.54 10.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) WD40 PF00400.32 RKP01511.1 - 6.3e-09 36.3 12.3 0.044 14.7 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Sel1 PF08238.12 RKP01512.1 - 1.3e-25 89.3 42.5 7.7e-06 26.4 0.3 11.9 11 1 0 11 11 11 9 Sel1 repeat TPR_2 PF07719.17 RKP01512.1 - 0.068 13.3 0.4 0.068 13.3 0.4 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01512.1 - 1.8 8.9 9.0 1.5 9.2 0.6 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP01512.1 - 5.6 7.0 6.4 1.9 8.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Alpha-amylase_C PF02806.18 RKP01513.1 - 3.4e-24 85.2 0.0 8.6e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 RKP01513.1 - 3.9e-17 62.4 0.0 7.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 RKP01513.1 - 5.1e-15 55.9 0.1 4.2e-12 46.3 0.0 2.2 1 1 0 2 2 2 2 Alpha amylase, catalytic domain Cation_efflux PF01545.21 RKP01514.1 - 2.2e-21 76.5 17.4 2.7e-21 76.2 17.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RKP01514.1 - 2.4e-11 43.6 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Mo25 PF08569.11 RKP01514.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Mo25-like RhodobacterPufX PF11511.8 RKP01514.1 - 0.16 11.6 0.8 0.62 9.7 0.8 2.0 1 0 0 1 1 1 0 Intrinsic membrane protein PufX VPS9 PF02204.18 RKP01516.1 - 4e-18 65.5 0.0 2.1e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain eIF3_N PF09440.10 RKP01517.1 - 4.7e-34 117.7 5.0 1e-33 116.6 5.0 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 RKP01517.1 - 1e-11 45.2 0.4 3.5e-11 43.5 0.0 2.1 2 1 0 2 2 2 1 PCI domain Ribosomal_L6e PF01159.19 RKP01519.1 - 4.9e-36 123.7 0.1 7.4e-36 123.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e PX PF00787.24 RKP01520.1 - 2.1e-24 85.7 0.2 4.6e-24 84.6 0.0 1.6 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 RKP01520.1 - 7e-06 25.8 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like Aldedh PF00171.22 RKP01521.1 - 6.1e-128 427.2 0.2 8.4e-128 426.8 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Atx10homo_assoc PF09759.9 RKP01523.1 - 7.2e-31 106.1 0.1 1.6e-30 105.0 0.1 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Solute_trans_a PF03619.16 RKP01525.1 - 7.2e-94 314.2 9.5 8.7e-94 313.9 9.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF5079 PF16882.5 RKP01525.1 - 0.0052 16.7 0.9 0.0052 16.7 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5079) Kinesin PF00225.23 RKP01526.1 - 3.5e-97 325.3 0.0 4.3e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP01526.1 - 1.1e-18 67.6 0.0 4.8e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Bac_DnaA PF00308.18 RKP01526.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein PhoH PF02562.16 RKP01526.1 - 0.16 11.4 0.0 0.79 9.1 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein COX14 PF14880.6 RKP01527.1 - 2.6e-05 24.0 0.3 4.5e-05 23.2 0.2 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c assembly RETICULATA-like PF11891.8 RKP01527.1 - 0.082 12.7 0.5 0.088 12.6 0.5 1.0 1 0 0 1 1 1 0 Protein RETICULATA-related AAA PF00004.29 RKP01528.1 - 9.9e-23 81.0 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKP01528.1 - 4.6e-07 30.2 0.0 6.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP01528.1 - 2.5e-06 28.0 0.6 6e-06 26.7 0.6 1.7 1 1 0 1 1 1 1 AAA ATPase domain Adeno_IVa2 PF02456.15 RKP01528.1 - 0.00066 18.6 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Adenovirus IVa2 protein TsaE PF02367.17 RKP01528.1 - 0.0054 16.7 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RKP01528.1 - 0.0092 16.2 0.0 0.018 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RKP01528.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 RKP01528.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 RKP01528.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 RKP01528.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AFG1_ATPase PF03969.16 RKP01528.1 - 0.041 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase ABC_tran PF00005.27 RKP01528.1 - 0.05 14.1 0.0 0.083 13.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 RKP01528.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 RKP01528.1 - 0.12 12.3 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 RKP01528.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.19 RKP01528.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 RKP01528.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Guanylate_kin PF00625.21 RKP01528.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase MMR_HSR1 PF01926.23 RKP01528.1 - 0.2 11.7 0.0 0.35 11.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.6 RKP01528.1 - 0.21 11.4 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RKP01528.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP-synt_G PF04718.15 RKP01529.1 - 2.8e-12 47.3 0.3 3.4e-12 47.1 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Sec2p PF06428.11 RKP01530.1 - 1.6e-17 63.2 16.3 1.6e-17 63.2 16.3 2.2 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 RKP01530.1 - 0.014 14.0 14.4 0.018 13.6 14.4 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 RKP01530.1 - 0.14 9.3 2.9 0.17 9.0 2.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5339 PF17274.2 RKP01530.1 - 0.35 11.8 6.9 4.2 8.3 1.5 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5339) DUF3584 PF12128.8 RKP01530.1 - 1.8 6.0 22.4 2.3 5.6 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) COG2 PF06148.11 RKP01530.1 - 1.9 8.6 10.3 1 9.4 2.9 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.19 RKP01530.1 - 4.4 5.1 9.7 6.1 4.6 9.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 RKP01530.1 - 5.1 6.4 13.4 9.8 5.4 13.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CLASP_N PF12348.8 RKP01531.1 - 1.7e-18 67.0 0.1 9.6e-16 58.0 0.1 3.0 3 0 0 3 3 3 2 CLASP N terminal MMS19_N PF14500.6 RKP01531.1 - 0.09 12.3 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Adap_comp_sub PF00928.21 RKP01532.1 - 5e-44 150.7 0.0 5.9e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 RKP01532.1 - 0.041 13.3 0.0 0.079 12.4 0.0 1.5 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain CPSF_A PF03178.15 RKP01533.1 - 6.6e-69 232.7 0.0 7.5e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region CBFD_NFYB_HMF PF00808.23 RKP01534.1 - 0.023 15.0 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone P16-Arc PF04699.14 RKP01535.1 - 3.5e-43 147.6 0.1 3.8e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2937 PF11157.8 RKP01535.1 - 0.0044 16.7 1.2 0.0067 16.2 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2937) Utp12 PF04003.12 RKP01535.1 - 0.023 15.0 0.0 0.049 13.9 0.0 1.5 2 0 0 2 2 2 0 Dip2/Utp12 Family Ribosomal_S19 PF00203.21 RKP01536.1 - 3.2e-34 116.7 1.0 4.5e-34 116.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 zf-C3HC4 PF00097.25 RKP01537.1 - 1e-10 41.3 5.9 1e-10 41.3 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP01537.1 - 3.1e-10 39.7 7.7 3.1e-10 39.7 7.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP01537.1 - 7.2e-09 35.5 7.5 2.1e-08 34.0 4.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKP01537.1 - 3.4e-08 33.4 6.9 3.4e-08 33.4 6.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RKP01537.1 - 3.8e-08 33.1 7.1 5.6e-08 32.5 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 RKP01537.1 - 8.9e-07 28.7 2.1 8.9e-07 28.7 2.1 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 RKP01537.1 - 1.1e-06 28.9 11.4 1.4e-06 28.6 7.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 RKP01537.1 - 1.8e-06 28.0 8.4 1.8e-06 28.0 8.4 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RKP01537.1 - 5.6e-05 22.9 10.9 0.0012 18.7 7.7 2.9 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 RKP01537.1 - 0.00072 19.3 4.4 0.00072 19.3 4.4 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain SAP PF02037.27 RKP01537.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-rbx1 PF12678.7 RKP01537.1 - 0.02 15.2 4.4 0.02 15.2 4.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-WRNIP1_ubi PF18279.1 RKP01537.1 - 0.071 13.8 0.1 0.071 13.8 0.1 3.4 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_10 PF16685.5 RKP01537.1 - 0.072 13.2 2.9 0.13 12.4 2.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 RKP01537.1 - 0.17 11.9 0.2 0.32 10.9 0.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 RKP01537.1 - 0.18 11.8 2.5 0.42 10.7 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.6 RKP01537.1 - 0.26 12.3 5.7 23 6.2 0.1 4.0 3 1 1 4 4 3 0 C2H2-type zinc finger zf-UDP PF14569.6 RKP01537.1 - 0.46 10.6 2.8 1.1 9.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 RKP01537.1 - 0.57 10.1 10.0 0.3 11.0 5.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 RKP01537.1 - 0.89 9.9 8.6 1.4 9.2 0.0 3.4 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 RKP01537.1 - 1.2 9.7 6.9 55 4.4 0.3 3.3 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 RKP01537.1 - 1.7 8.7 7.9 25 5.0 3.6 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 RKP01537.1 - 1.8 8.4 5.5 1.3 8.9 2.3 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_9 PF14369.6 RKP01537.1 - 4.3 7.7 8.9 4 7.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon Prok-RING_1 PF14446.6 RKP01537.1 - 5.3 7.1 6.6 12 5.9 0.1 3.2 2 1 2 4 4 4 0 Prokaryotic RING finger family 1 GAGA PF09237.11 RKP01537.1 - 5.4 6.9 10.9 1.4 8.8 0.2 3.1 3 0 0 3 3 3 0 GAGA factor zf-RING_11 PF17123.5 RKP01537.1 - 7.5 6.4 7.7 0.89 9.4 2.4 2.2 2 1 1 3 3 3 0 RING-like zinc finger Tub PF01167.18 RKP01539.1 - 1.3e-33 116.8 0.1 1.4e-33 116.7 0.1 1.0 1 0 0 1 1 1 1 Tub family Prefoldin_2 PF01920.20 RKP01541.1 - 1.2e-18 67.0 7.4 1.5e-18 66.7 7.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.11 RKP01541.1 - 0.0032 17.5 0.9 0.0032 17.5 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Occludin_ELL PF07303.13 RKP01541.1 - 0.0093 16.7 2.5 3.4 8.4 1.3 2.1 2 0 0 2 2 2 2 Occludin homology domain Syntaxin_2 PF14523.6 RKP01541.1 - 0.016 15.6 7.0 0.26 11.7 2.0 2.3 2 1 0 2 2 2 0 Syntaxin-like protein YscO PF07321.12 RKP01541.1 - 0.021 14.8 3.3 0.046 13.7 0.2 1.9 1 1 1 2 2 2 0 Type III secretion protein YscO TPR_MLP1_2 PF07926.12 RKP01541.1 - 0.028 14.5 7.6 0.33 11.0 1.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Alpha-2-MRAP_C PF06401.11 RKP01541.1 - 0.03 14.3 2.7 0.036 14.0 2.7 1.0 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain YabA PF06156.13 RKP01541.1 - 0.033 14.8 2.6 2.6 8.7 0.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF4298 PF14131.6 RKP01541.1 - 0.05 13.6 3.2 1.6 8.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) GLTSCR1 PF15249.6 RKP01541.1 - 0.053 14.0 1.4 0.07 13.6 0.4 1.7 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein Syntaxin-6_N PF09177.11 RKP01541.1 - 0.071 13.7 3.2 0.43 11.2 3.2 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ZapB PF06005.12 RKP01541.1 - 0.12 12.8 10.5 2 8.9 10.5 2.1 1 1 0 1 1 1 0 Cell division protein ZapB FliD_C PF07195.12 RKP01541.1 - 0.27 10.6 4.9 0.54 9.6 4.9 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF5446 PF17522.2 RKP01541.1 - 0.47 10.7 3.2 0.48 10.6 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DivIVA PF05103.13 RKP01541.1 - 0.52 10.4 7.4 1.5 9.0 7.4 1.7 1 1 0 1 1 1 0 DivIVA protein Snapin_Pallidin PF14712.6 RKP01541.1 - 0.61 10.6 6.3 17 5.9 0.1 2.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF148 PF02520.17 RKP01541.1 - 0.67 10.1 8.6 0.83 9.8 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 KASH_CCD PF14662.6 RKP01541.1 - 0.74 9.6 9.9 6.6 6.5 0.2 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 RKP01541.1 - 0.99 9.4 8.7 1.6 8.7 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 RKP01541.1 - 1.1 9.5 10.0 0.52 10.5 1.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein TMF_DNA_bd PF12329.8 RKP01541.1 - 4.8 7.3 10.0 2.5 8.1 0.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 RKP01541.1 - 5.4 7.3 8.5 9.8 6.5 1.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RNA_pol_Rpb5_C PF01191.19 RKP01542.1 - 9.6e-33 111.9 0.1 2.3e-32 110.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 RKP01542.1 - 1.2e-26 93.1 0.7 1.9e-26 92.4 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Rubrerythrin PF02915.17 RKP01542.1 - 0.005 17.2 0.1 0.0078 16.6 0.1 1.4 1 0 0 1 1 1 1 Rubrerythrin PDT PF00800.18 RKP01542.1 - 0.052 13.4 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydratase DDE_Tnp_1 PF01609.21 RKP01542.1 - 0.099 12.3 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 Transposase DDE domain TRAPP PF04051.16 RKP01544.1 - 1e-28 99.9 0.0 1.2e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component NDUFB10 PF10249.9 RKP01545.1 - 0.006 17.1 0.3 0.0061 17.1 0.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Vinculin PF01044.19 RKP01546.1 - 2.5e-47 161.8 40.1 1.6e-25 89.6 6.8 2.8 1 1 1 2 2 2 2 Vinculin family F_actin_bind PF08919.10 RKP01546.1 - 0.47 10.6 3.4 6.7 6.9 0.0 4.1 4 1 0 4 4 4 0 F-actin binding DnaJ_C PF01556.18 RKP01547.1 - 1e-40 139.2 0.0 1.3e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKP01547.1 - 6.9e-24 83.8 4.1 9.5e-24 83.3 4.1 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RKP01547.1 - 8.8e-10 38.8 17.3 1.5e-09 38.1 17.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 RKP01547.1 - 6.9 6.7 7.6 14 5.7 0.8 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RKP01547.1 - 8.6 6.5 9.5 5.3 7.2 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon RIB43A PF05914.12 RKP01548.1 - 2.3e-55 187.9 83.2 3.9e-55 187.1 83.2 1.3 1 1 0 1 1 1 1 RIB43A Endomucin PF07010.12 RKP01549.1 - 2.2 8.2 20.4 3.7 7.4 20.4 1.3 1 0 0 1 1 1 0 Endomucin Mitofilin PF09731.9 RKP01549.1 - 3.2 6.5 19.5 0.038 12.9 7.7 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein GREB1 PF15782.5 RKP01549.1 - 6.5 3.7 5.7 8.2 3.4 5.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_hydro_26 PF02156.15 RKP01550.1 - 5.8e-06 25.9 1.1 0.00013 21.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 Cnd2 PF05786.14 RKP01551.1 - 2.2e-84 284.6 0.0 2.4e-83 281.2 0.0 2.3 1 1 0 1 1 1 1 Condensin complex subunit 2 GET2 PF08690.10 RKP01553.1 - 0.013 15.2 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 PAP2 PF01569.21 RKP01554.1 - 5.4e-25 87.8 5.1 5.4e-25 87.8 5.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily HemY_N PF07219.13 RKP01554.1 - 0.093 12.9 0.1 0.093 12.9 0.1 3.4 2 2 2 4 4 4 0 HemY protein N-terminus Sugar_tr PF00083.24 RKP01554.1 - 0.12 11.2 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter EptA_B_N PF08019.12 RKP01554.1 - 0.35 10.7 0.0 0.35 10.7 0.0 2.4 4 0 0 4 4 4 0 Phosphoethanolamine transferase EptA/EptB Nup188 PF10487.9 RKP01555.1 - 2.1e-25 88.9 0.0 3.1e-19 68.5 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF2370 PF10176.9 RKP01556.1 - 1.8e-18 67.0 0.6 1.9e-18 67.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) PI3_PI4_kinase PF00454.27 RKP01557.1 - 1.6e-32 113.3 0.0 6e-21 75.4 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RKP01557.1 - 2.7e-24 85.6 0.2 6e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Peptidase_S8_N PF16361.5 RKP01557.1 - 0.077 13.5 0.1 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 N-terminal of Subtilase family Myosin_head PF00063.21 RKP01558.1 - 5.1e-239 795.0 0.0 7.8e-239 794.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 RKP01558.1 - 0.00025 21.5 0.3 0.0055 17.1 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 RKP01558.1 - 0.033 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKP01558.1 - 0.048 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RKP01558.1 - 0.092 13.3 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter LssY_C PF14067.6 RKP01558.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 LssY C-terminus TsaE PF02367.17 RKP01558.1 - 0.14 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IQ PF00612.27 RKP01558.1 - 0.87 9.6 20.2 0.042 13.6 3.3 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif Roc PF08477.13 RKP01559.1 - 3.2e-11 43.5 0.0 4.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RKP01559.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 RKP01559.1 - 1.8e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 RKP01559.1 - 0.005 17.2 0.0 0.0061 17.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 RKP01559.1 - 0.059 13.9 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RKP01559.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gtr1_RagA PF04670.12 RKP01559.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKP01559.1 - 0.18 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FHA PF00498.26 RKP01560.1 - 7.4e-10 39.0 0.1 1.3e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 FHA domain Acetyltransf_1 PF00583.25 RKP01561.1 - 6.4e-15 55.4 0.0 7.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKP01561.1 - 1.5e-08 34.9 0.3 2.6e-08 34.2 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKP01561.1 - 2.8e-08 33.8 0.0 3.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKP01561.1 - 0.068 13.1 0.0 0.23 11.4 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Snf7 PF03357.21 RKP01562.1 - 1e-46 158.7 19.2 1.2e-46 158.5 19.2 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 RKP01562.1 - 0.002 18.6 13.2 0.014 15.8 0.7 3.6 1 1 3 4 4 4 2 Nucleopolyhedrovirus P10 protein DUF848 PF05852.11 RKP01562.1 - 3.8 7.6 11.3 5 7.2 9.6 2.1 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) PEP-utilisers_N PF05524.13 RKP01562.1 - 7 6.9 10.9 2.7 8.2 3.8 2.5 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Acetyltransf_1 PF00583.25 RKP01563.1 - 1.7e-10 41.1 0.2 2.2e-10 40.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKP01563.1 - 1.3e-06 28.7 0.1 1.9e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKP01563.1 - 2.8e-05 24.0 0.1 3.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TspO_MBR PF03073.15 RKP01564.1 - 2e-29 102.4 14.3 2.3e-29 102.2 14.3 1.0 1 0 0 1 1 1 1 TspO/MBR family LIM PF00412.22 RKP01565.1 - 2.1e-11 43.8 8.2 3.3e-11 43.2 8.2 1.3 1 0 0 1 1 1 1 LIM domain Cep57_CLD PF14073.6 RKP01565.1 - 0.025 14.6 1.4 0.04 13.9 1.4 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Csm1_N PF18504.1 RKP01565.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 RKP01565.1 - 0.32 10.8 1.7 0.58 10.0 1.7 1.3 1 0 0 1 1 1 0 Septum formation initiator zf-RRN7 PF11781.8 RKP01565.1 - 0.51 10.1 3.0 0.84 9.4 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PriA_CRR PF18319.1 RKP01565.1 - 0.62 10.1 10.3 0.75 9.8 4.5 2.4 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-FCS PF06467.14 RKP01565.1 - 0.89 9.6 7.7 3.3 7.7 1.3 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DZR PF12773.7 RKP01565.1 - 0.91 9.6 6.4 0.98 9.5 4.5 2.0 2 0 0 2 2 2 0 Double zinc ribbon TPP_enzyme_N PF02776.18 RKP01566.1 - 2.5e-57 193.2 0.2 2.6e-55 186.7 0.1 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 RKP01566.1 - 2e-52 177.0 0.7 6.8e-50 168.8 0.1 3.3 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 RKP01566.1 - 1.3e-36 125.4 0.7 2.2e-36 124.6 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_transf_20 PF00982.21 RKP01567.1 - 9.6e-160 532.3 0.0 1.3e-159 531.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RKP01567.1 - 3e-73 245.8 0.0 5.2e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase LSM PF01423.22 RKP01568.1 - 3.6e-08 33.0 0.0 4.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 RKP01568.1 - 0.062 13.4 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain INO80_Ies4 PF08193.11 RKP01568.1 - 0.55 10.2 6.8 0.64 10.0 6.8 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 DUF4821 PF16092.5 RKP01569.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4821) DDHD PF02862.17 RKP01570.1 - 0.27 11.3 5.8 4 7.5 3.0 2.5 2 0 0 2 2 2 0 DDHD domain PRP1_N PF06424.12 RKP01570.1 - 4.5 7.7 10.0 19 5.7 5.6 2.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Vps52 PF04129.12 RKP01571.1 - 7.1e-103 345.1 0.0 1e-101 341.2 0.0 2.1 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 RKP01571.1 - 3.2e-06 25.9 4.0 0.00031 19.3 0.7 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 Patatin PF01734.22 RKP01572.1 - 1.7e-16 61.1 1.5 3.3e-15 56.8 0.8 2.2 1 1 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 RKP01572.1 - 9.6e-13 48.0 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) HSP20 PF00011.21 RKP01573.1 - 2.4e-07 30.8 0.0 2.1e-06 27.8 0.0 2.0 1 1 1 2 2 2 1 Hsp20/alpha crystallin family CLPTM1 PF05602.12 RKP01574.1 - 4.7e-110 368.6 0.0 6e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) AA_permease_2 PF13520.6 RKP01575.1 - 1.6e-35 122.8 41.2 2.1e-35 122.4 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Vasohibin PF14822.6 RKP01577.1 - 5.3e-39 133.9 0.0 1e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 Vasohibin WD40 PF00400.32 RKP01578.1 - 2e-15 56.9 15.6 0.0078 17.0 0.4 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01578.1 - 9.5e-05 22.6 0.3 0.0044 17.3 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 RKP01578.1 - 0.0024 16.9 2.6 0.0044 16.0 0.0 2.6 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain PQQ PF01011.21 RKP01578.1 - 0.015 15.2 0.5 12 6.1 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_2 PF13360.6 RKP01578.1 - 0.02 14.5 0.1 0.11 12.0 0.1 2.2 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 RKP01578.1 - 0.047 12.3 2.3 0.66 8.5 0.0 3.2 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Topo_Zn_Ribbon PF08272.11 RKP01578.1 - 0.08 12.6 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like LigD_N PF13298.6 RKP01578.1 - 0.14 12.5 0.1 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) Cnn_1N PF07989.11 RKP01579.1 - 8e-07 29.1 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 SlyX PF04102.12 RKP01579.1 - 2.3 8.9 9.2 3.2 8.4 1.0 3.2 2 1 1 3 3 3 0 SlyX Ras PF00071.22 RKP01580.1 - 3.2e-66 221.9 0.1 3.7e-66 221.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP01580.1 - 6.4e-36 123.2 0.0 1.1e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP01580.1 - 7.3e-15 54.9 0.1 1.1e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKP01580.1 - 1.3e-06 28.1 0.1 5e-06 26.2 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RKP01580.1 - 1.1e-05 24.9 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKP01580.1 - 1.6e-05 24.9 0.1 0.00016 21.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKP01580.1 - 4.1e-05 23.5 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 RKP01580.1 - 0.0027 16.9 3.2 0.032 13.4 0.5 2.7 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 RKP01580.1 - 0.0033 17.0 0.0 0.032 13.8 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 RKP01580.1 - 0.0058 16.1 0.1 0.0072 15.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3963 PF13124.6 RKP01580.1 - 0.032 14.2 0.4 0.067 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_29 PF13555.6 RKP01580.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RKP01580.1 - 0.091 13.1 0.0 0.26 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 RKP01580.1 - 0.1 11.7 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 RKP01580.1 - 0.14 12.4 0.1 0.52 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain CLP_protease PF00574.23 RKP01581.1 - 1.3e-81 272.9 0.0 1.5e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 RKP01581.1 - 0.072 12.1 0.2 0.091 11.7 0.2 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase AMPK1_CBM PF16561.5 RKP01582.1 - 3.6e-09 36.7 1.0 5.6e-09 36.1 1.0 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 RKP01582.1 - 0.032 14.1 0.4 0.064 13.2 0.4 1.4 1 0 0 1 1 1 0 Starch binding domain Mito_carr PF00153.27 RKP01583.1 - 3.6e-49 164.6 4.9 8.3e-17 60.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.25 RKP01584.1 - 2.2e-25 89.2 0.0 2.4e-24 85.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKP01584.1 - 7e-19 68.3 0.0 4.1e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKP01584.1 - 0.0071 16.3 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 KR domain HEAT PF02985.22 RKP01585.1 - 0.031 14.5 2.8 0.23 11.8 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 RKP01585.1 - 0.035 14.1 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 RKP01586.1 - 7.4e-69 232.0 0.0 8.4e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01586.1 - 7.8e-35 120.4 0.0 9.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01586.1 - 1.3e-06 27.9 0.0 3.3e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Rad52_Rad22 PF04098.15 RKP01588.1 - 2.4e-50 170.4 0.0 2.7e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein BCS1_N PF08740.11 RKP01589.1 - 1.3e-33 116.6 0.0 1.8e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 RKP01589.1 - 2.5e-15 57.1 0.0 1.1e-14 55.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP01589.1 - 0.00032 21.1 0.2 0.0018 18.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 RKP01589.1 - 0.00037 20.1 0.0 0.016 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RKP01589.1 - 0.0019 18.2 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RKP01589.1 - 0.0041 17.3 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKP01589.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 RKP01589.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 RKP01589.1 - 0.03 14.0 0.3 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RKP01589.1 - 0.045 14.3 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RKP01589.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKP01589.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 RKP01589.1 - 0.093 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKP01589.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RKP01589.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RKP01589.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 RKP01589.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.6 RKP01589.1 - 0.16 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RKP01589.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Gemini_AC4_5 PF04807.12 RKP01590.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region BUD22 PF09073.10 RKP01591.1 - 3.8 6.7 6.3 6.7 5.9 6.3 1.3 1 0 0 1 1 1 0 BUD22 Tropomyosin_1 PF12718.7 RKP01592.1 - 7.5e-22 78.0 42.6 8.8e-22 77.8 42.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 RKP01592.1 - 8.8e-09 35.1 42.1 3.3e-05 23.4 26.8 2.4 1 1 1 2 2 2 2 Tropomyosin DHR10 PF18595.1 RKP01592.1 - 0.031 14.3 48.1 0.059 13.4 20.5 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain GAS PF13851.6 RKP01592.1 - 0.051 12.9 38.8 1.1 8.6 38.8 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DRTGG PF07085.12 RKP01592.1 - 0.11 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 DRTGG domain Dynamitin PF04912.14 RKP01592.1 - 0.55 9.5 28.5 0.87 8.8 28.5 1.4 1 1 0 1 1 1 0 Dynamitin Laminin_II PF06009.12 RKP01592.1 - 0.62 10.1 20.9 0.28 11.2 1.7 2.4 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 RKP01592.1 - 1.4 9.0 39.3 3.2 7.8 17.3 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 RKP01592.1 - 1.4 8.9 42.2 3.6 7.6 4.1 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 RKP01592.1 - 1.8 7.0 26.6 0.44 9.1 14.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 RKP01592.1 - 1.9 8.6 15.8 2 8.5 4.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 RKP01592.1 - 2 8.2 14.6 2.2 8.1 5.9 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 RKP01592.1 - 2.1 8.8 34.4 1.2e+02 3.0 34.1 2.0 1 1 0 1 1 1 0 Fez1 FemAB PF02388.16 RKP01592.1 - 2.1 7.2 27.4 0.67 8.8 9.7 2.0 1 1 1 2 2 2 0 FemAB family Noelin-1 PF12308.8 RKP01592.1 - 2.1 8.4 13.3 2.2 8.3 2.3 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF4200 PF13863.6 RKP01592.1 - 2.3 8.6 43.1 1.3 9.5 25.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Vps5 PF09325.10 RKP01592.1 - 2.3 7.7 25.5 3.7 7.0 7.7 2.4 1 1 0 2 2 2 0 Vps5 C terminal like UPF0242 PF06785.11 RKP01592.1 - 3.3 7.8 39.6 39 4.3 19.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 RKP01592.1 - 3.5 7.8 19.4 2.2 8.5 6.5 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 RKP01592.1 - 3.7 4.9 36.6 5.3 4.4 36.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 RKP01592.1 - 4.2 7.9 11.2 1.4 9.4 1.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BST2 PF16716.5 RKP01592.1 - 4.3 8.0 31.5 2.9 8.6 14.2 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Sec34 PF04136.15 RKP01592.1 - 5.1 7.0 16.3 3 7.7 2.7 2.5 1 1 1 3 3 3 0 Sec34-like family ADIP PF11559.8 RKP01592.1 - 5.6 7.0 33.3 2 8.5 5.4 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CREPT PF16566.5 RKP01592.1 - 6.2 7.0 28.0 0.29 11.3 12.8 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DASH_Spc19 PF08287.11 RKP01592.1 - 7.2 6.5 35.6 13 5.7 3.2 2.8 1 1 1 2 2 2 0 Spc19 Baculo_PEP_C PF04513.12 RKP01592.1 - 7.3 6.6 10.0 13 5.8 0.1 2.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.6 RKP01592.1 - 7.4 6.1 30.7 1.2e+02 2.0 30.7 1.9 1 1 0 1 1 1 0 TMCO5 family T3SS_basalb_I PF17001.5 RKP01592.1 - 7.7 7.2 12.9 3.3 8.4 2.1 2.6 1 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF948 PF06103.11 RKP01592.1 - 7.8 6.8 8.0 28 5.0 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cluap1 PF10234.9 RKP01592.1 - 9.7 5.5 31.7 0.38 10.1 10.1 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 ERM PF00769.19 RKP01592.1 - 9.9 5.9 50.2 0.068 13.0 6.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Velvet PF11754.8 RKP01593.1 - 3.3e-49 168.1 3.0 9.4e-34 117.5 0.0 2.0 1 1 1 2 2 2 2 Velvet factor ABC_tran PF00005.27 RKP01594.1 - 1.5e-45 155.1 0.5 4.8e-24 85.4 0.0 3.1 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 RKP01594.1 - 2.4e-24 85.2 0.3 2.4e-24 85.2 0.3 1.8 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 RKP01594.1 - 1.7e-14 54.4 2.8 0.012 15.4 0.0 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RKP01594.1 - 5.7e-13 48.8 0.0 0.00052 19.5 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RKP01594.1 - 4.8e-06 26.2 0.1 0.04 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RKP01594.1 - 5.6e-06 27.0 11.7 0.022 15.2 0.0 4.3 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 RKP01594.1 - 7.8e-06 26.2 1.7 0.25 11.6 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RKP01594.1 - 1.1e-05 25.4 1.5 0.29 10.8 0.0 3.8 5 0 0 5 5 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 RKP01594.1 - 1.3e-05 25.1 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 RKP01594.1 - 2.2e-05 24.9 3.3 0.028 14.8 0.2 2.8 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.12 RKP01594.1 - 2.5e-05 24.3 0.1 0.034 14.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 RKP01594.1 - 4.2e-05 24.0 0.0 0.39 11.2 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 RKP01594.1 - 0.00022 20.9 0.2 0.26 10.9 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 RKP01594.1 - 0.00032 20.7 0.4 0.65 10.1 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 RKP01594.1 - 0.00038 20.7 0.1 0.49 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 RKP01594.1 - 0.00077 19.4 0.1 0.7 9.8 0.0 2.7 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.12 RKP01594.1 - 0.001 18.4 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 RKP01594.1 - 0.0015 18.3 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RKP01594.1 - 0.002 17.9 3.2 1 9.1 0.1 3.7 3 2 0 3 3 3 1 AAA domain Roc PF08477.13 RKP01594.1 - 0.0027 17.9 0.1 3.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 RKP01594.1 - 0.0035 17.9 0.0 6.3 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 RKP01594.1 - 0.0057 16.7 0.0 2.9 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 RKP01594.1 - 0.0057 16.6 0.3 2.3 8.2 0.0 2.7 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 RKP01594.1 - 0.0083 15.8 0.4 2.8 7.5 0.1 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.14 RKP01594.1 - 0.0087 16.0 0.0 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DLIC PF05783.11 RKP01594.1 - 0.012 14.4 0.0 0.91 8.3 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_13 PF13166.6 RKP01594.1 - 0.013 14.2 0.4 5.7 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 RKP01594.1 - 0.014 15.6 0.2 0.18 12.0 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 RKP01594.1 - 0.019 14.7 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 RKP01594.1 - 0.02 15.1 4.1 2.9 8.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 RKP01594.1 - 0.022 14.3 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 RKP01594.1 - 0.022 14.7 0.0 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 RKP01594.1 - 0.031 13.8 0.0 11 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RKP01594.1 - 0.032 13.4 0.2 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 RKP01594.1 - 0.047 13.4 0.0 9.6 5.9 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 RKP01594.1 - 0.048 13.2 0.9 4 7.0 0.0 3.0 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 RKP01594.1 - 0.057 13.5 3.4 2 8.5 0.0 2.9 4 0 0 4 4 2 0 Helicase HerA, central domain Septin PF00735.18 RKP01594.1 - 0.058 12.7 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 RKP01594.1 - 0.068 13.6 0.1 12 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 RKP01594.1 - 0.13 12.2 0.2 9.4 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 RKP01594.1 - 0.21 11.6 0.9 7.7 6.5 0.0 3.3 4 0 0 4 4 4 0 Dynamin family DUF3584 PF12128.8 RKP01594.1 - 3.4 5.0 13.6 0.82 7.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) MARVEL PF01284.23 RKP01595.1 - 1.4e-14 54.3 19.8 2.4e-14 53.5 19.8 1.3 1 1 0 1 1 1 1 Membrane-associating domain BatA PF07584.11 RKP01595.1 - 0.26 11.7 0.0 0.26 11.7 0.0 3.4 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal DUF2076 PF09849.9 RKP01595.1 - 5.5 6.9 5.5 7.7 6.5 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MARVEL PF01284.23 RKP01596.1 - 1.6e-15 57.4 8.6 2.5e-15 56.8 8.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3177 PF11375.8 RKP01596.1 - 0.14 11.9 4.7 0.18 11.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3177) DUF2631 PF10939.8 RKP01596.1 - 0.5 10.2 1.9 2 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) Viral_Beta_CD PF04530.12 RKP01596.1 - 0.81 10.0 2.5 0.59 10.4 0.1 2.1 1 1 2 3 3 3 0 Viral Beta C/D like family VTC PF09359.10 RKP01597.1 - 1.2e-93 313.5 0.0 2.1e-93 312.7 0.0 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 RKP01597.1 - 1.6e-17 63.7 2.9 3.7e-17 62.5 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 RKP01597.1 - 2.6e-14 54.0 15.0 1e-06 28.9 0.9 4.0 2 1 1 4 4 4 3 SPX domain DUF4287 PF14117.6 RKP01597.1 - 0.037 14.2 0.1 5 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) SRP19 PF01922.17 RKP01597.1 - 0.14 13.1 0.3 1.7 9.6 0.0 2.4 1 1 1 2 2 2 0 SRP19 protein Lebercilin PF15619.6 RKP01597.1 - 3.6 7.2 11.9 2 8.0 3.4 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 RKP01597.1 - 5 7.2 5.3 1 9.4 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 RKP01598.1 - 1.6e-37 129.1 0.0 1e-23 84.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 RKP01598.1 - 1.3e-31 110.3 17.3 1.7e-17 64.0 5.4 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 RKP01598.1 - 0.00019 21.1 0.1 0.019 14.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 RKP01598.1 - 0.075 13.6 0.7 0.42 11.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RKP01598.1 - 0.08 13.3 0.6 11 6.3 0.4 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 RKP01598.1 - 0.18 12.1 0.1 21 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 RKP01598.1 - 0.19 11.8 0.8 1.1 9.4 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 RKP01598.1 - 0.3 11.1 1.7 13 5.8 0.0 2.5 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.6 RKP01598.1 - 0.31 10.7 1.0 0.86 9.3 0.0 2.2 4 0 0 4 4 4 0 AAA domain Methyltransf_31 PF13847.6 RKP01599.1 - 4.7e-10 39.5 0.0 7.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP01599.1 - 9.4e-10 39.1 0.2 2.1e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 RKP01599.1 - 9.5e-06 24.8 0.1 0.0002 20.5 0.0 2.2 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.18 RKP01599.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 RKP01599.1 - 2.2e-05 24.0 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 RKP01599.1 - 3.3e-05 23.5 0.1 6.6e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 RKP01599.1 - 0.00044 20.8 0.1 0.0011 19.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP01599.1 - 0.00098 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP01599.1 - 0.004 17.9 0.0 0.0099 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 RKP01599.1 - 0.0078 16.2 0.0 0.053 13.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 RKP01599.1 - 0.011 15.2 0.8 0.016 14.6 0.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 RKP01599.1 - 0.013 15.0 0.2 0.022 14.3 0.2 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 RKP01599.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF1794 PF08768.11 RKP01599.1 - 0.14 12.1 0.0 0.7 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) BTB PF00651.31 RKP01600.1 - 4.1e-05 23.8 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Cwf_Cwc_15 PF04889.12 RKP01600.1 - 2.4 7.8 6.7 0.54 9.9 1.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M24 PF00557.24 RKP01601.1 - 1.3e-35 123.0 0.6 1.3e-33 116.5 0.6 2.5 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RKP01601.1 - 2.3e-18 66.1 0.0 1.2e-16 60.6 0.0 2.3 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Mito_fiss_reg PF05308.11 RKP01601.1 - 8.9 6.3 9.4 6.3 6.8 5.0 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator MutS_V PF00488.21 RKP01602.1 - 6.3e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKP01602.1 - 4.7e-06 26.9 0.0 8.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain III DUF3022 PF11226.8 RKP01602.1 - 0.032 14.7 10.0 2.1 8.8 6.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3022) DHHC PF01529.20 RKP01603.1 - 2e-28 99.2 0.0 3.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1358 PF07096.11 RKP01603.1 - 1.8 8.6 5.2 2.6 8.1 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) Aa_trans PF01490.18 RKP01604.1 - 8.2e-53 179.6 21.3 9.6e-53 179.4 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF155 PF02582.14 RKP01605.1 - 1.4e-37 129.4 0.0 2.7e-37 128.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Proteasome PF00227.26 RKP01606.1 - 3.3e-58 196.3 0.2 4e-58 196.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKP01606.1 - 7.4e-14 51.1 0.1 1.3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NUDE_C PF04880.13 RKP01607.1 - 4.4 7.7 10.7 2.7 8.4 9.3 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region AMPK1_CBM PF16561.5 RKP01608.1 - 3.3e-12 46.5 0.0 8.1e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase Glyco_H_20C_C PF18088.1 RKP01609.1 - 7.9e-48 162.9 0.3 2.2e-47 161.4 0.0 1.7 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 RKP01609.1 - 6.2e-09 35.7 0.0 1.7e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain UCH PF00443.29 RKP01610.1 - 5.7e-70 235.8 0.0 6.5e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP01610.1 - 4.3e-21 75.8 0.0 2.8e-19 69.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ICL PF00463.21 RKP01612.1 - 6.7e-259 859.7 0.5 7.6e-259 859.5 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family ADSL_C PF10397.9 RKP01612.1 - 0.054 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Zw10 PF06248.13 RKP01613.1 - 0.15 10.6 0.0 7.3 5.0 0.0 2.7 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 FtsX PF02687.21 RKP01614.1 - 1.6e-11 44.5 27.3 2.9e-10 40.5 9.6 6.0 6 0 0 6 6 6 3 FtsX-like permease family Nucleoporin_N PF08801.11 RKP01615.1 - 4.3e-52 177.3 0.0 4.8e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Nup133 N terminal like Arrestin_C PF02752.22 RKP01616.1 - 3.8e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 RKP01616.1 - 0.03 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain WW PF00397.26 RKP01617.1 - 6.7e-15 54.9 11.1 1.1e-08 34.9 2.2 3.3 4 0 0 4 4 4 2 WW domain FF PF01846.19 RKP01617.1 - 2.8e-05 24.2 0.0 0.00018 21.6 0.0 2.4 3 0 0 3 3 3 1 FF domain TMEM51 PF15345.6 RKP01618.1 - 0.091 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 QueC PF06508.13 RKP01618.1 - 0.17 11.4 0.1 0.21 11.0 0.1 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Arf PF00025.21 RKP01619.1 - 8.5e-44 149.1 0.0 1e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RKP01619.1 - 1e-18 67.5 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP01619.1 - 1.1e-15 57.9 0.0 2.1e-15 57.0 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RKP01619.1 - 5.7e-08 32.8 0.0 9.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RKP01619.1 - 2.4e-07 30.4 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RKP01619.1 - 5.5e-06 25.8 0.2 0.0011 18.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RKP01619.1 - 3.7e-05 23.2 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RKP01619.1 - 0.0055 16.3 0.0 0.22 11.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RKP01619.1 - 0.028 13.9 0.4 0.1 12.1 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B VirE PF05272.11 RKP01619.1 - 0.048 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Dynamin_N PF00350.23 RKP01619.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 RKP01619.1 - 0.13 12.2 0.0 18 5.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase adh_short PF00106.25 RKP01620.1 - 2.4e-26 92.4 0.0 3.6e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKP01620.1 - 4.4e-15 55.9 0.9 5.9e-15 55.5 0.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKP01620.1 - 3.7e-08 33.5 7.4 2.4e-07 30.8 7.4 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RKP01620.1 - 5.7e-06 26.0 0.2 8.6e-06 25.4 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 RKP01620.1 - 0.016 14.9 0.4 0.025 14.2 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 RKP01620.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 RKP01620.1 - 0.045 13.6 4.6 0.19 11.6 4.6 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 RKP01620.1 - 0.067 13.5 0.6 0.16 12.3 0.6 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 RKP01620.1 - 0.085 13.3 0.3 0.13 12.7 0.3 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UPF0016 PF01169.19 RKP01620.1 - 0.086 13.2 2.2 0.13 12.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 3HCDH_N PF02737.18 RKP01620.1 - 0.24 11.2 1.0 0.38 10.6 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF218 PF02698.17 RKP01620.1 - 1.3 9.0 3.6 2.7 8.0 3.5 1.8 1 1 0 1 1 1 0 DUF218 domain DFP PF04127.15 RKP01620.1 - 2.1 8.1 4.7 3.3 7.5 4.7 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RhoGEF PF00621.20 RKP01621.1 - 1.7e-48 165.2 0.2 2.5e-48 164.7 0.2 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 RKP01621.1 - 1.4e-08 35.2 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 PH domain RAI16-like PF10257.9 RKP01622.1 - 2.4e-38 131.9 0.0 3.5e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Sterol-sensing PF12349.8 RKP01623.1 - 6.4e-40 136.5 1.8 6.4e-40 136.5 1.8 1.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 RKP01623.1 - 4.7e-20 71.3 0.7 7.3e-20 70.7 0.7 1.1 1 0 0 1 1 1 1 Patched family TMEM171 PF15471.6 RKP01626.1 - 0.84 8.6 2.1 1.3 7.9 2.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DNA_pol_phi PF04931.13 RKP01627.1 - 0.34 9.0 6.2 0.48 8.5 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4667 PF15700.5 RKP01627.1 - 0.75 9.9 17.9 0.7 9.9 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) RNA_pol_Rpc4 PF05132.14 RKP01627.1 - 5.1 7.5 6.3 20 5.6 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase III RPC4 zinc_ribbon_10 PF10058.9 RKP01628.1 - 0.2 11.4 0.1 0.46 10.2 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4200 PF13863.6 RKP01629.1 - 3.4e-26 92.0 17.4 3.4e-26 92.0 17.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) JIP_LZII PF16471.5 RKP01629.1 - 0.024 14.8 1.9 0.024 14.8 1.9 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Phosphodiest PF01663.22 RKP01629.1 - 0.29 10.7 0.8 0.5 9.9 0.1 1.5 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase UPF0242 PF06785.11 RKP01629.1 - 0.83 9.7 22.0 1.2 9.2 1.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 RKP01629.1 - 1.2 9.2 9.2 6.3 6.9 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4464 PF14713.6 RKP01629.1 - 5.2 6.6 8.9 0.13 11.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4464) COG2 PF06148.11 RKP01629.1 - 8.3 6.5 10.0 6.6 6.8 0.4 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cofilin_ADF PF00241.20 RKP01630.1 - 8.3e-18 64.3 0.0 9.1e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ski2_N PF17911.1 RKP01630.1 - 0.14 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Ski2 N-terminal region Oxidored_q6 PF01058.22 RKP01631.1 - 6.5e-22 77.8 0.0 9.5e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tmemb_14 PF03647.13 RKP01631.1 - 0.064 14.0 0.1 0.12 13.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C Cation_ATPase_C PF00689.21 RKP01632.1 - 2.1e-47 161.2 2.3 5.5e-47 159.8 2.3 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RKP01632.1 - 1.2e-35 122.7 0.9 1.2e-35 122.7 0.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RKP01632.1 - 3.7e-23 82.9 0.1 2.2e-22 80.4 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP01632.1 - 6.8e-16 58.1 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RKP01632.1 - 2.1e-08 33.8 0.0 4.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKP01632.1 - 4.4e-06 26.6 0.0 0.00031 20.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DoxX_3 PF13781.6 RKP01632.1 - 0.094 13.4 0.6 0.34 11.6 0.6 1.9 1 0 0 1 1 1 0 DoxX-like family PRIMA1 PF16101.5 RKP01632.1 - 0.29 11.2 0.9 16 5.6 0.2 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pox_A14 PF05767.12 RKP01632.1 - 1.8 8.7 4.3 2.4 8.4 0.1 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Brr6_like_C_C PF10104.9 RKP01633.1 - 3.5e-39 133.6 0.0 4.1e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Mito_carr PF00153.27 RKP01634.1 - 2.2e-26 91.6 5.0 2.2e-12 46.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein YjcB PF15940.5 RKP01634.1 - 0.046 13.9 0.2 0.47 10.7 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function Sedlin_N PF04628.13 RKP01635.1 - 4.4e-22 78.6 0.0 5.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4129 PF13559.6 RKP01635.1 - 0.19 12.0 4.7 0.35 11.2 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) Hat1_N PF10394.9 RKP01636.1 - 2.5e-34 118.8 0.0 9.5e-34 116.9 0.0 1.9 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus RNA_pol_Rpc4 PF05132.14 RKP01637.1 - 6.7e-12 46.1 0.0 6.7e-12 46.1 0.0 2.8 2 2 1 3 3 3 1 RNA polymerase III RPC4 RNase_PH PF01138.21 RKP01638.1 - 1.7e-29 103.0 0.1 2.3e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RKP01638.1 - 1.8e-07 31.1 0.0 4.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 EF-hand_8 PF13833.6 RKP01639.1 - 8.9e-20 70.3 2.6 1.5e-09 37.5 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 RKP01639.1 - 2.7e-19 67.2 6.6 1.6e-05 24.1 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 RKP01639.1 - 2e-15 57.0 3.9 0.0013 19.2 0.0 4.1 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 RKP01639.1 - 3.2e-15 54.7 7.0 0.00012 21.7 0.1 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 RKP01639.1 - 3.5e-15 54.7 3.9 9.6e-05 21.7 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 RKP01639.1 - 0.011 15.7 0.4 1 9.3 0.0 3.3 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand Jun PF03957.13 RKP01639.1 - 0.11 12.3 1.7 0.22 11.4 1.7 1.5 1 0 0 1 1 1 0 Jun-like transcription factor SAP PF02037.27 RKP01640.1 - 4.9e-11 42.1 0.7 4.9e-11 42.1 0.7 1.8 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 RKP01640.1 - 0.042 13.7 0.1 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain HeH PF12949.7 RKP01640.1 - 0.08 12.7 0.3 0.18 11.5 0.3 1.7 1 1 0 1 1 1 0 HeH/LEM domain Syja_N PF02383.18 RKP01641.1 - 6.7e-83 278.7 0.0 8.2e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain SNAPc_SNAP43 PF09808.9 RKP01642.1 - 3.1e-11 43.6 0.1 0.00015 21.8 0.0 3.2 3 0 0 3 3 3 3 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 PQ-loop PF04193.14 RKP01643.1 - 2.8e-33 113.5 16.7 1.5e-17 63.1 0.9 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 RKP01643.1 - 0.0035 18.2 1.0 0.11 13.4 0.0 2.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF2781 PF10914.8 RKP01643.1 - 0.0078 16.6 3.7 0.22 11.9 1.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2781) Claudin_2 PF13903.6 RKP01643.1 - 2.1 8.0 8.0 0.61 9.8 1.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SCO1-SenC PF02630.14 RKP01644.1 - 3.9e-45 153.1 0.0 1.2e-43 148.2 0.0 2.3 1 1 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 RKP01644.1 - 8.4e-07 28.9 0.0 3.9e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKP01644.1 - 0.02 14.6 0.0 0.055 13.2 0.0 1.8 1 1 1 2 2 2 0 Redoxin HMG_box PF00505.19 RKP01646.1 - 1.8e-18 66.7 0.0 2.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKP01646.1 - 9.9e-05 22.9 0.0 0.00012 22.6 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain DUF4746 PF15928.5 RKP01646.1 - 0.026 13.9 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mito_carr PF00153.27 RKP01647.1 - 2e-53 178.3 0.8 2.2e-19 69.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 RKP01649.1 - 2e-14 53.6 0.0 1.9e-09 37.3 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain APH PF01636.23 RKP01649.1 - 1.8e-05 24.8 1.0 1.8e-05 24.8 1.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 RKP01649.1 - 0.00046 19.6 0.0 0.0024 17.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP01649.1 - 0.0049 16.3 0.1 0.0091 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP01649.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 RKP01649.1 - 0.3 10.0 0.0 0.44 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CHASE3 PF05227.13 RKP01649.1 - 1 9.2 4.2 2.4 8.1 4.2 1.5 1 0 0 1 1 1 0 CHASE3 domain RRM_1 PF00076.22 RKP01650.1 - 4.8e-11 42.3 0.0 4.4e-05 23.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP01650.1 - 0.0092 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif DUF2561 PF10812.8 RKP01650.1 - 0.098 12.7 0.1 0.098 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) IQ PF00612.27 RKP01651.1 - 3.2e-08 32.7 23.7 9.9e-05 21.8 2.1 4.5 4 0 0 4 4 4 3 IQ calmodulin-binding motif CLAMP PF14769.6 RKP01652.1 - 4.4e-07 30.3 0.0 0.0038 17.6 0.0 2.1 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 DUF2498 PF10692.9 RKP01652.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) PUB PF09409.10 RKP01653.1 - 2e-14 53.3 0.0 2.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 PUB domain MOFRL PF05161.13 RKP01653.1 - 0.0043 17.2 0.5 0.015 15.5 0.5 1.9 1 0 0 1 1 1 1 MOFRL family LRR_8 PF13855.6 RKP01654.1 - 1.2e-22 79.4 6.4 4.4e-10 39.2 0.5 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 RKP01654.1 - 1e-20 73.5 15.3 2.7e-05 24.4 0.1 3.9 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP01654.1 - 1.8e-09 36.8 1.5 3.6 8.5 0.0 5.4 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 RKP01654.1 - 2.9e-07 30.0 7.2 0.97 9.7 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 RKP01654.1 - 5.1e-05 22.8 0.7 0.15 11.6 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat Ribosomal_S13 PF00416.22 RKP01655.1 - 3.6e-53 179.3 3.1 4.2e-53 179.1 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 RKP01655.1 - 0.0069 15.2 0.0 0.011 14.5 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Syntaxin-6_N PF09177.11 RKP01655.1 - 0.041 14.4 0.1 0.085 13.4 0.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1822 PF08852.11 RKP01655.1 - 0.074 12.1 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) MA3 PF02847.17 RKP01656.1 - 1.4e-25 89.5 0.2 2.6e-25 88.6 0.2 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 RKP01656.1 - 1.2e-17 64.3 0.0 3.8e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 MIF4G domain GOLD_2 PF13897.6 RKP01656.1 - 0.05 14.1 0.6 0.085 13.4 0.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.14 RKP01656.1 - 0.13 10.5 0.4 0.17 10.2 0.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 RKP01656.1 - 0.21 11.3 4.1 0.43 10.3 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) FAM176 PF14851.6 RKP01656.1 - 0.38 10.4 3.0 0.7 9.5 3.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF5523 PF17661.1 RKP01656.1 - 0.47 10.1 5.7 0.67 9.6 5.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Nop14 PF04147.12 RKP01656.1 - 1.3 7.1 7.7 2 6.5 7.7 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RKP01656.1 - 1.4 8.2 7.4 1.9 7.7 7.4 1.1 1 0 0 1 1 1 0 BUD22 PAP_assoc PF03828.19 RKP01657.1 - 7e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 RKP01657.1 - 8.5e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 RKP01657.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Rap_GAP PF02145.15 RKP01658.1 - 1e-54 184.9 0.0 1.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP TPR_14 PF13428.6 RKP01659.1 - 6.1e-09 36.0 0.6 0.011 16.4 0.1 5.3 3 2 3 6 6 5 2 Tetratricopeptide repeat Suf PF05843.14 RKP01659.1 - 1.4e-07 31.8 3.1 7.3e-06 26.2 0.7 3.0 1 1 0 2 2 2 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 RKP01659.1 - 5.4e-07 29.0 1.6 0.25 10.4 0.0 3.3 1 1 2 3 3 3 3 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 RKP01659.1 - 6.1e-07 29.7 3.2 0.026 15.1 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKP01659.1 - 1.2e-06 28.3 0.3 0.046 13.9 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKP01659.1 - 4.8e-06 26.3 0.0 0.12 12.5 0.0 3.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01659.1 - 4.2e-05 23.8 0.7 0.014 15.7 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKP01659.1 - 8.8e-05 22.9 2.2 0.013 16.0 0.4 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP01659.1 - 0.00071 19.8 0.2 0.0032 17.7 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 RKP01659.1 - 0.00076 19.7 0.5 0.11 12.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKP01659.1 - 0.0012 19.0 0.0 0.0058 16.7 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKP01659.1 - 0.0078 15.9 0.3 0.084 12.6 0.0 2.6 1 1 1 2 2 2 1 TPR repeat TPR_16 PF13432.6 RKP01659.1 - 0.016 15.9 0.1 0.11 13.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP01659.1 - 0.028 14.2 1.2 3.8 7.5 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Nairo_nucleo PF02477.15 RKP01659.1 - 0.034 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein TPR_7 PF13176.6 RKP01659.1 - 0.067 13.3 0.0 1.6 8.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Imm52 PF15579.6 RKP01659.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 52 BTAD PF03704.17 RKP01659.1 - 0.087 13.3 2.9 1.7 9.1 0.4 3.1 1 1 2 3 3 3 0 Bacterial transcriptional activator domain RPN7 PF10602.9 RKP01659.1 - 0.089 12.5 0.3 13 5.4 0.1 2.8 1 1 2 3 3 3 0 26S proteasome subunit RPN7 DUF5638 PF18688.1 RKP01659.1 - 0.14 12.5 1.0 2.4 8.5 0.0 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5638) PNP_UDP_1 PF01048.20 RKP01660.1 - 1.9e-45 155.0 4.2 2.5e-45 154.6 4.2 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.27 RKP01661.1 - 3.4e-10 39.7 0.3 0.0047 16.8 0.0 5.5 6 0 0 6 6 6 3 Mitochondrial carrier protein Pkinase PF00069.25 RKP01662.1 - 4.9e-16 58.9 0.0 7.2e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 RKP01662.1 - 2.5e-12 47.1 4.4 0.033 15.1 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 RKP01662.1 - 0.00015 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RKP01662.1 - 0.0019 18.3 5.1 20 5.8 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat APH PF01636.23 RKP01662.1 - 0.0029 17.6 0.1 0.0094 15.9 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family ETF PF01012.21 RKP01663.1 - 4.6e-48 163.5 2.2 5.6e-48 163.2 2.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain C2 PF00168.30 RKP01664.1 - 0.00023 21.4 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain RPEL PF02755.15 RKP01665.1 - 0.03 14.0 2.3 0.099 12.4 0.2 2.6 2 0 0 2 2 2 0 RPEL repeat Glyco_hydro_71 PF03659.14 RKP01666.1 - 9.6e-85 284.6 0.7 9.6e-85 284.6 0.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Trefoil PF00088.18 RKP01666.1 - 4.6e-06 26.4 6.5 4.6e-06 26.4 6.5 1.7 2 0 0 2 2 2 1 Trefoil (P-type) domain TAF4 PF05236.14 RKP01667.1 - 1.4e-18 67.6 10.5 4.6e-16 59.4 10.5 3.3 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family RRP36 PF06102.12 RKP01668.1 - 2e-35 122.2 18.9 2e-35 122.2 18.9 1.6 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 CCAP PF11105.8 RKP01668.1 - 0.034 14.1 0.1 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a DUF1676 PF07898.13 RKP01668.1 - 9.9 6.2 8.9 0.5 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) UPF0029 PF01205.19 RKP01669.1 - 3.6e-21 75.5 0.0 5.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 NUDIX PF00293.28 RKP01670.1 - 3e-22 79.0 0.2 4.1e-22 78.6 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.29 RKP01671.1 - 6.1e-20 71.7 0.0 1.9e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01671.1 - 2.9e-18 66.2 0.0 1.8e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RKP01671.1 - 3.1e-17 63.0 4.7 1.2e-16 61.2 4.7 2.1 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 RKP01671.1 - 6.3e-15 55.0 0.0 1.8e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 RKP01671.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit VASt PF16016.5 RKP01672.1 - 1.2e-26 94.0 0.0 2.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 RKP01672.1 - 4.6e-24 85.4 2.5 6.6e-24 84.9 0.6 1.9 2 0 0 2 2 2 1 BAR domain of APPL family GRAM PF02893.20 RKP01672.1 - 3.6e-13 49.4 0.2 6.9e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 GRAM domain PH PF00169.29 RKP01672.1 - 4.1e-12 46.5 0.1 8.8e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RKP01672.1 - 0.0016 18.8 0.2 0.0059 17.0 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain BAR PF03114.18 RKP01672.1 - 0.075 12.7 5.1 0.79 9.3 5.1 2.4 1 1 0 1 1 1 0 BAR domain bPH_3 PF14470.6 RKP01672.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial PH domain DUF1864 PF08933.11 RKP01672.1 - 0.12 11.2 0.1 0.22 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) SIT PF15330.6 RKP01672.1 - 0.26 11.7 1.2 0.74 10.3 1.2 1.8 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LMBR1 PF04791.16 RKP01673.1 - 0.086 11.7 4.5 0.088 11.7 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cu_amine_oxid PF01179.20 RKP01673.1 - 0.1 11.5 6.6 0.14 11.1 6.6 1.2 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Period_C PF12114.8 RKP01673.1 - 0.2 11.2 19.0 0.31 10.6 19.0 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF4569 PF15133.6 RKP01673.1 - 0.48 10.1 20.1 1.4 8.6 14.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) eIF-3_zeta PF05091.12 RKP01673.1 - 0.71 8.8 18.4 1.1 8.2 18.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 RKP01673.1 - 1.2 8.9 12.1 2 8.2 12.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 RKP01673.1 - 1.4 8.3 12.2 2.3 7.6 12.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hamartin PF04388.12 RKP01673.1 - 3 6.4 20.2 3.7 6.1 20.2 1.1 1 0 0 1 1 1 0 Hamartin protein SLC12 PF03522.15 RKP01673.1 - 3.3 6.6 13.6 4.7 6.1 13.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DUF3292 PF11696.8 RKP01673.1 - 5.6 5.2 13.1 9.2 4.5 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4449 PF14613.6 RKP01673.1 - 8.1 6.5 18.8 0.18 11.9 11.6 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4449) DUF2838 PF10998.8 RKP01675.1 - 6.7e-37 126.1 4.1 6.7e-37 126.1 4.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) AAA_28 PF13521.6 RKP01677.1 - 3.3e-17 63.2 0.0 4.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 RKP01677.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase RNase_P_p30 PF01876.16 RKP01678.1 - 1.4e-45 155.5 0.0 1.5e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit p30 Auto_anti-p27 PF06677.12 RKP01679.1 - 5.5e-17 61.6 1.3 8.1e-17 61.1 1.3 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rubella_E2 PF05749.11 RKP01679.1 - 0.0037 16.8 8.9 0.0053 16.3 0.1 2.3 2 0 0 2 2 2 1 Rubella membrane glycoprotein E2 Arf PF00025.21 RKP01680.1 - 3.2e-43 147.2 0.0 4.1e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RKP01680.1 - 1.1e-10 41.2 0.0 2.6e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RKP01680.1 - 1.7e-10 41.2 0.0 3.1e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RKP01680.1 - 1.3e-09 37.9 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 RKP01680.1 - 1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKP01680.1 - 5.2e-07 29.4 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain G-alpha PF00503.20 RKP01680.1 - 1.6e-06 27.6 0.1 0.038 13.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 RKP01680.1 - 2.6e-06 26.9 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 RKP01680.1 - 0.00067 19.2 0.1 0.00095 18.7 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 RKP01680.1 - 0.048 13.4 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 RKP01680.1 - 0.054 12.3 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 RKP01680.1 - 0.056 13.2 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 RKP01680.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 RKP01680.1 - 0.093 13.1 0.0 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RKP01680.1 - 0.14 12.4 0.0 0.59 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 RKP01680.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Peptidase_C12 PF01088.21 RKP01681.1 - 6.8e-47 159.9 0.0 7.7e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 cNMP_binding PF00027.29 RKP01682.1 - 2.5e-28 98.0 0.0 2.6e-14 53.1 0.0 4.6 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.22 RKP01682.1 - 1.2e-20 74.6 4.8 1.1e-19 71.5 4.8 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Rep_fac_C PF08542.11 RKP01683.1 - 6.7e-24 84.1 0.0 3.4e-23 81.9 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 RKP01683.1 - 1.4e-12 48.2 0.0 2.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 RKP01683.1 - 1.8e-12 47.3 0.0 3.7e-10 39.8 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 RKP01683.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP01683.1 - 1.8e-06 28.5 0.0 0.00011 22.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP01683.1 - 4.9e-06 26.9 0.0 0.017 15.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 RKP01683.1 - 4.7e-05 23.2 0.0 9.7e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 RKP01683.1 - 5e-05 22.8 0.0 0.00062 19.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 RKP01683.1 - 0.00013 21.8 0.0 0.00034 20.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 RKP01683.1 - 0.00023 21.2 0.0 0.00052 20.0 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 RKP01683.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 RKP01683.1 - 0.0014 18.0 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_11 PF13086.6 RKP01683.1 - 0.0025 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKP01683.1 - 0.0028 18.0 0.1 0.01 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKP01683.1 - 0.014 15.0 0.0 0.04 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 RKP01683.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF5119 PF17145.4 RKP01683.1 - 0.015 15.2 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) NTPase_1 PF03266.15 RKP01683.1 - 0.02 14.8 0.4 0.1 12.5 0.1 2.1 1 1 0 2 2 2 0 NTPase AAA_assoc_2 PF16193.5 RKP01683.1 - 0.021 15.1 0.0 0.059 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_30 PF13604.6 RKP01683.1 - 0.026 14.2 0.0 0.22 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RKP01683.1 - 0.026 14.8 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 RKP01683.1 - 0.033 13.9 0.1 1.5 8.5 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 RKP01683.1 - 0.044 14.3 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 RKP01683.1 - 0.055 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 RKP01683.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 RKP01683.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 RKP01683.1 - 0.072 12.8 0.1 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 RKP01683.1 - 0.074 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 RKP01683.1 - 0.1 11.5 0.0 0.27 10.2 0.0 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 RKP01683.1 - 0.15 11.3 0.3 6.9 5.8 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Diphthamide_syn PF01866.17 RKP01684.1 - 4.2e-112 374.5 0.0 4.8e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Epimerase PF01370.21 RKP01684.1 - 0.11 11.9 0.3 7.4 5.9 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 RKP01685.1 - 3.1e-15 56.2 0.0 4.6e-11 42.6 0.0 3.0 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKP01685.1 - 1.3e-10 41.0 0.2 9.6e-10 38.2 0.1 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.11 RKP01685.1 - 0.00014 20.7 0.2 0.00032 19.5 0.1 1.5 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 RKP01685.1 - 0.00019 21.4 0.9 0.02 14.9 0.2 3.5 3 1 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 RKP01685.1 - 0.00043 19.9 3.6 0.001 18.7 1.7 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 RKP01685.1 - 0.012 15.5 6.9 0.015 15.1 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Dehydrin PF00257.19 RKP01685.1 - 0.19 12.3 0.5 0.6 10.6 0.0 1.9 2 0 0 2 2 2 0 Dehydrin CPSF73-100_C PF11718.8 RKP01686.1 - 4.3e-36 124.5 0.0 1.2e-35 123.0 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 RKP01686.1 - 1.4e-29 102.6 0.0 2.9e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 RKP01686.1 - 1.2e-20 74.4 0.2 4.1e-20 72.6 0.2 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 RKP01686.1 - 4.8e-20 71.8 0.0 9.5e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 RKP01686.1 - 7.7e-13 48.2 0.1 7.7e-13 48.2 0.1 2.0 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta_lactamase3 PF17030.5 RKP01686.1 - 2.4e-06 26.9 0.0 4.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 RKP01686.1 - 5.4e-06 26.4 0.1 5.4e-06 26.4 0.1 2.9 4 1 0 4 4 4 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 RKP01686.1 - 3.1e-05 23.6 0.6 3.1e-05 23.6 0.6 3.6 3 0 0 3 3 3 1 Beta-lactamase superfamily domain DUF4982 PF16355.5 RKP01686.1 - 0.054 13.5 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) DUF3446 PF11928.8 RKP01687.1 - 3.1e-06 27.4 13.8 3.5e-06 27.2 8.7 2.2 2 0 0 2 2 2 1 Early growth response N-terminal domain Syntaphilin PF15290.6 RKP01687.1 - 0.39 10.3 5.7 0.49 10.0 5.7 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp SR-25 PF10500.9 RKP01687.1 - 0.62 9.6 13.5 0.93 9.1 13.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RKP01687.1 - 0.94 10.2 9.0 1.6 9.5 9.0 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Actin PF00022.19 RKP01688.1 - 2.2e-32 112.2 0.0 9e-25 87.1 0.0 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 RKP01688.1 - 3.3e-06 26.2 0.0 2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein DUF624 PF04854.14 RKP01688.1 - 0.23 11.6 1.5 18 5.5 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF624 ANTH PF07651.16 RKP01689.1 - 1.9e-31 109.1 2.0 8.7e-20 70.8 0.7 2.0 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.20 RKP01689.1 - 0.058 13.4 0.1 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 ENTH domain JHY PF15261.6 RKP01690.1 - 0.54 11.0 4.3 6.1 7.6 4.3 2.1 1 1 0 1 1 1 0 Jhy protein Ribosomal_S21e PF01249.18 RKP01691.1 - 9.2e-37 125.0 0.0 1e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FH2 PF02181.23 RKP01692.1 - 5.4e-16 58.7 0.0 1.1e-10 41.2 0.0 3.7 3 1 0 3 3 3 3 Formin Homology 2 Domain UPF0444 PF15475.6 RKP01692.1 - 0.02 15.1 0.3 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 RNA_pol_Rpb4 PF03874.16 RKP01694.1 - 1.5e-13 51.2 0.0 3.2e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 p53-inducible11 PF14936.6 RKP01695.1 - 0.01 15.9 1.7 0.016 15.3 1.7 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 PrgI PF12666.7 RKP01695.1 - 4.4 8.1 6.8 0.33 11.7 1.5 1.8 2 0 0 2 2 2 0 PrgI family protein Dynamin_M PF01031.20 RKP01697.1 - 5.7e-104 347.3 0.0 1.3e-103 346.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 RKP01697.1 - 6.6e-56 189.0 0.0 1.4e-55 187.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 RKP01697.1 - 1.5e-28 98.8 3.1 1.5e-28 98.8 3.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 RKP01697.1 - 3.4e-05 23.9 0.2 0.00033 20.7 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RKP01697.1 - 0.11 12.8 0.0 0.45 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain UbiA PF01040.18 RKP01698.1 - 5.6e-29 101.2 21.4 7.1e-29 100.8 21.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ATXN-1_C PF12547.8 RKP01698.1 - 0.13 12.6 0.3 0.34 11.3 0.3 1.7 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator TcpE PF12648.7 RKP01698.1 - 0.5 10.9 0.1 0.5 10.9 0.1 3.2 1 1 3 4 4 4 0 TcpE family ATP-synt_C PF00137.21 RKP01699.1 - 5e-30 103.6 32.9 9.6e-18 64.3 12.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SPC22 PF04573.12 RKP01700.1 - 1.7e-44 151.3 0.0 2e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF1494 PF07379.11 RKP01700.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) Fe-S_biosyn PF01521.20 RKP01702.1 - 3e-16 59.6 0.0 3.6e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Glyco_trans_2_3 PF13632.6 RKP01704.1 - 6.9e-26 91.4 5.6 6.9e-26 91.4 5.6 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKP01704.1 - 2.6e-12 47.1 0.7 3.6e-12 46.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 VWD PF00094.25 RKP01705.1 - 0.00055 20.2 0.3 0.00055 20.2 0.3 3.2 3 0 0 3 3 3 1 von Willebrand factor type D domain RGM_N PF06535.12 RKP01705.1 - 0.0019 18.4 1.6 0.015 15.5 0.1 2.8 2 0 0 2 2 2 1 Repulsive guidance molecule (RGM) N-terminus C8 PF08742.11 RKP01705.1 - 0.0058 17.0 5.2 0.013 15.9 0.3 2.6 2 0 0 2 2 2 1 C8 domain EGF_2 PF07974.13 RKP01705.1 - 0.02 15.3 12.2 0.02 15.3 12.2 2.4 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 RKP01705.1 - 1.1 9.6 11.1 0.074 13.4 5.3 2.1 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 RKP01705.1 - 1.4 9.0 11.5 3.1 8.0 11.5 1.6 1 0 0 1 1 1 0 Tenascin EGF domain DUF4334 PF14232.6 RKP01707.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) FH2 PF02181.23 RKP01708.1 - 3.4e-92 309.4 4.0 6.1e-92 308.6 4.0 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 RKP01708.1 - 2e-34 118.8 0.3 5.6e-34 117.4 0.2 1.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 RKP01708.1 - 6e-33 114.1 0.0 3.3e-32 111.7 0.0 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Stevor PF17410.2 RKP01708.1 - 0.011 15.4 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1682 PF07946.14 RKP01708.1 - 0.029 13.6 6.7 1.4 8.1 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) EMC3_TMCO1 PF01956.16 RKP01708.1 - 0.13 12.0 0.8 0.43 10.3 0.8 1.9 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Claudin_2 PF13903.6 RKP01709.1 - 0.00057 19.7 0.1 0.00057 19.7 0.1 2.2 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 RKP01709.1 - 0.0069 16.3 2.3 0.06 13.2 2.3 2.1 1 1 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family PMP22_Claudin PF00822.20 RKP01709.1 - 0.022 14.7 2.5 0.044 13.7 2.4 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 RKP01709.1 - 0.032 14.2 3.7 0.19 11.7 3.7 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4293 PF14126.6 RKP01709.1 - 0.035 14.3 0.8 0.073 13.3 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) 7TM_GPCR_Str PF10326.9 RKP01709.1 - 0.038 13.3 1.1 0.056 12.8 1.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str SecD_SecF PF02355.16 RKP01709.1 - 0.12 11.7 0.8 0.18 11.1 0.8 1.4 1 1 0 1 1 1 0 Protein export membrane protein Clc-like PF07062.12 RKP01709.1 - 0.24 10.8 4.1 0.35 10.3 0.1 2.1 2 0 0 2 2 2 0 Clc-like RNase_P_pop3 PF08228.11 RKP01710.1 - 7.1e-05 22.9 0.0 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 Costars PF14705.6 RKP01711.1 - 1.7e-25 89.0 0.1 1.8e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Costars NDUFA12 PF05071.16 RKP01712.1 - 3e-10 40.8 0.0 4.6e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CCDC53 PF10152.9 RKP01712.1 - 0.57 10.6 2.1 0.76 10.2 2.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Prenylcys_lyase PF07156.14 RKP01713.1 - 1.4e-56 192.2 0.0 1.8e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 RKP01713.1 - 1.5e-16 60.7 0.0 2.5e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RKP01713.1 - 7.7e-08 32.4 3.4 2.4e-07 30.9 0.2 3.2 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RKP01713.1 - 0.00073 19.2 3.2 0.082 12.5 1.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 RKP01713.1 - 0.65 9.0 5.1 0.88 8.6 5.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Arm PF00514.23 RKP01714.1 - 2.7e-18 65.3 16.0 4.4e-05 23.4 0.5 8.5 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKP01714.1 - 5.4e-05 23.5 5.5 0.061 13.7 0.0 5.1 2 2 3 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 RKP01714.1 - 0.00025 21.5 14.5 0.032 14.8 0.5 6.0 4 3 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 RKP01714.1 - 0.0083 16.3 1.1 11 6.6 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat Cnd3 PF12719.7 RKP01714.1 - 0.15 11.2 0.1 0.63 9.2 0.0 2.0 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Spt5_N PF11942.8 RKP01714.1 - 4.4 8.3 10.4 49 5.0 0.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal EF-hand_6 PF13405.6 RKP01715.1 - 0.0004 20.1 0.0 9.4 6.5 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RKP01715.1 - 0.0012 19.2 0.5 8.2 7.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RKP01715.1 - 0.088 12.4 0.0 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 EF hand Tubulin PF00091.25 RKP01716.1 - 5.6e-69 232.3 0.0 1e-68 231.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RKP01716.1 - 1.1e-43 148.4 0.1 1.7e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RKP01716.1 - 1.1e-05 25.7 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RKP01716.1 - 0.00083 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RKP01716.1 - 0.008 15.4 0.0 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin like LRR_8 PF13855.6 RKP01717.1 - 4.2e-39 132.1 38.7 1.7e-08 34.1 4.3 7.7 7 1 1 8 8 8 7 Leucine rich repeat Guanylate_cyc PF00211.20 RKP01717.1 - 2.3e-25 89.3 0.0 2.8e-12 46.6 0.0 3.0 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 RKP01717.1 - 2.3e-22 78.7 38.7 0.00017 21.9 0.1 9.7 8 3 2 11 11 11 6 Leucine Rich repeats (2 copies) PP2C PF00481.21 RKP01717.1 - 7.3e-05 22.5 0.0 0.0011 18.7 0.0 2.7 1 1 0 2 2 2 1 Protein phosphatase 2C LRR_1 PF00560.33 RKP01717.1 - 0.0036 17.6 30.6 3 8.8 0.0 10.8 11 2 0 11 11 11 1 Leucine Rich Repeat LRR_6 PF13516.6 RKP01717.1 - 0.49 10.6 36.1 2 8.7 0.7 10.6 11 0 0 11 11 11 0 Leucine Rich repeat XPG_I PF00867.18 RKP01718.1 - 1.6e-05 25.2 0.4 0.00022 21.5 0.2 2.3 2 0 0 2 2 2 1 XPG I-region DUF936 PF06075.12 RKP01718.1 - 0.05 12.5 0.9 0.082 11.8 0.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Smg4_UPF3 PF03467.15 RKP01719.1 - 4.3e-10 39.9 0.1 9.3e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Smg-4/UPF3 family Ribosomal_L30_N PF08079.12 RKP01720.1 - 2.8e-21 75.6 15.3 4.5e-21 74.9 15.3 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 RKP01720.1 - 1.5e-17 63.2 1.4 1.9e-17 62.9 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e ABC_membrane PF00664.23 RKP01723.1 - 7.6e-97 324.2 23.8 1.1e-53 182.7 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKP01723.1 - 1e-68 230.1 0.0 1.2e-33 116.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKP01723.1 - 4.3e-11 42.7 0.1 0.0059 16.1 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RKP01723.1 - 1.2e-08 34.2 1.0 0.0012 17.7 0.1 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 RKP01723.1 - 2.3e-07 30.3 1.3 0.00061 19.1 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.6 RKP01723.1 - 2.4e-07 31.1 0.1 0.0034 17.7 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 RKP01723.1 - 1.1e-06 28.2 0.2 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RKP01723.1 - 1.3e-05 25.7 8.0 0.053 13.9 0.2 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 RKP01723.1 - 0.00015 21.6 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain G-alpha PF00503.20 RKP01723.1 - 0.00016 21.0 0.0 0.48 9.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 RKP01723.1 - 0.00024 21.0 0.8 5.4 6.7 0.1 3.9 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 RKP01723.1 - 0.00027 20.9 0.0 0.64 9.9 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_5 PF07728.14 RKP01723.1 - 0.00048 20.1 0.0 1.4 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RKP01723.1 - 0.0012 18.5 0.5 1.7 8.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 RKP01723.1 - 0.0018 18.2 0.0 0.067 13.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 RKP01723.1 - 0.0025 18.4 0.0 3.5 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RKP01723.1 - 0.0032 17.6 0.3 0.17 12.0 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain APS_kinase PF01583.20 RKP01723.1 - 0.0051 16.7 0.0 1.2 9.0 0.0 3.1 3 0 0 3 3 3 1 Adenylylsulphate kinase DUF815 PF05673.13 RKP01723.1 - 0.0052 16.0 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RKP01723.1 - 0.01 16.0 0.0 4.9 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 RKP01723.1 - 0.015 15.0 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3632 PF12311.8 RKP01723.1 - 0.017 15.6 0.6 0.05 14.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) AAA_24 PF13479.6 RKP01723.1 - 0.027 14.2 0.0 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RKP01723.1 - 0.032 13.6 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.6 RKP01723.1 - 0.054 13.7 1.2 20 5.5 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 RKP01723.1 - 0.088 12.9 0.5 23 5.1 0.1 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 RKP01723.1 - 0.1 12.2 0.3 21 4.7 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 RKP01723.1 - 0.1 13.0 0.0 10 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 RKP01723.1 - 0.15 11.2 0.2 8.7 5.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 RKP01723.1 - 0.48 10.1 15.4 2.4 7.8 0.1 4.4 3 2 0 4 4 2 0 AAA domain AAA_28 PF13521.6 RKP01723.1 - 0.52 10.5 10.5 1.8 8.8 0.1 3.2 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 RKP01723.1 - 0.61 10.5 3.1 9.9 6.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain SWIRM PF04433.17 RKP01724.1 - 1.5e-29 102.2 0.1 2.5e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 RKP01724.1 - 1.1e-18 67.0 7.7 2.1e-18 66.0 7.7 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 RKP01724.1 - 5.5e-13 48.9 0.1 1e-12 48.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKP01724.1 - 9.9e-07 28.9 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 RKP01724.1 - 0.088 12.6 3.9 0.22 11.3 3.9 1.6 1 1 0 1 1 1 0 Zinc finger, ZZ type ADD_ATRX PF17981.1 RKP01724.1 - 0.092 12.6 2.2 0.11 12.4 0.8 1.8 2 0 0 2 2 2 0 Cysteine Rich ADD domain N6-adenineMlase PF10237.9 RKP01725.1 - 3.5e-45 153.7 0.0 3.9e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Membr_traf_MHD PF10540.9 RKP01726.1 - 0.0023 18.1 0.7 0.2 11.8 0.8 2.4 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain MMM1 PF10296.9 RKP01727.1 - 2.6e-08 33.3 0.0 2.1e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 GOLD_2 PF13897.6 RKP01728.1 - 0.0017 18.9 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 2 2 Golgi-dynamics membrane-trafficking Polyketide_cyc2 PF10604.9 RKP01728.1 - 0.003 17.8 0.2 0.003 17.8 0.2 3.5 4 0 0 4 4 4 1 Polyketide cyclase / dehydrase and lipid transport F1F0-ATPsyn_F PF10791.9 RKP01730.1 - 3e-16 59.6 0.4 4.5e-16 59.1 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 RKP01730.1 - 0.035 14.5 0.2 0.077 13.4 0.2 1.6 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f IGPS PF00218.21 RKP01731.1 - 2.8e-76 256.1 0.0 3.8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 RKP01731.1 - 6e-45 153.3 0.0 8.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKP01731.1 - 5.7e-07 29.5 0.2 3.3e-06 27.0 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 RKP01731.1 - 0.055 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain FSA_C PF10479.9 RKP01731.1 - 0.3 9.2 3.0 0.46 8.6 3.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ribosomal_S7e PF01251.18 RKP01732.1 - 1.1e-78 263.2 1.4 1.3e-78 263.0 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PPR_2 PF13041.6 RKP01733.1 - 0.0022 18.1 0.0 0.14 12.4 0.0 3.5 4 0 0 4 4 4 1 PPR repeat family WD40 PF00400.32 RKP01734.1 - 5.9e-21 74.4 6.3 1.6e-06 28.8 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01734.1 - 6.7e-16 58.4 0.4 0.011 16.0 0.0 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 RKP01734.1 - 0.0042 17.0 0.0 0.66 9.9 0.0 2.5 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term eIF2A PF08662.11 RKP01734.1 - 0.015 15.2 0.0 1.3 8.9 0.0 2.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 RKP01734.1 - 0.059 12.4 0.0 0.41 9.6 0.0 2.1 3 0 0 3 3 3 0 Coatomer WD associated region Ge1_WD40 PF16529.5 RKP01734.1 - 0.077 11.9 0.4 0.83 8.5 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Inh PF02974.14 RKP01734.1 - 0.19 11.8 0.6 9.4 6.4 0.1 3.2 3 1 2 5 5 5 0 Protease inhibitor Inh Bromodomain PF00439.25 RKP01735.1 - 1.6e-16 60.1 0.0 1.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Bromodomain D123 PF07065.14 RKP01736.1 - 7.6e-103 343.9 0.0 8.9e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 RKP01736.1 - 0.00014 22.0 0.2 0.00014 22.0 0.2 1.8 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 RKP01736.1 - 0.0011 18.8 0.1 0.0026 17.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 Nup84_Nup100 PF04121.13 RKP01737.1 - 1.5e-124 416.8 0.0 1.8e-124 416.5 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DEAD PF00270.29 RKP01738.1 - 6.8e-34 117.2 0.0 4.2e-33 114.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01738.1 - 5.5e-29 100.8 0.0 1.9e-27 95.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP01738.1 - 0.02 14.9 0.0 0.19 11.7 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 RKP01738.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L26 PF16906.5 RKP01738.1 - 0.12 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal eIF-1a PF01176.19 RKP01739.1 - 0.00027 20.7 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 2 Translation initiation factor 1A / IF-1 Aldedh PF00171.22 RKP01740.1 - 1e-163 545.1 5.1 1.2e-163 544.9 5.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DcpS_C PF11969.8 RKP01742.1 - 3.3e-17 63.0 0.0 2.7e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 RKP01742.1 - 3.5e-14 53.3 0.0 7.7e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 RKP01742.1 - 4.9e-11 42.9 0.0 1.1e-10 41.8 0.0 1.6 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-Sec23_Sec24 PF04810.15 RKP01742.1 - 0.18 11.9 0.5 0.3 11.2 0.5 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger W2 PF02020.18 RKP01743.1 - 1.1e-19 70.4 1.2 2.5e-19 69.2 0.4 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Methyltransf_3 PF01596.17 RKP01743.1 - 0.027 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase AsiA PF09010.10 RKP01743.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Anti-Sigma Factor A PTPA PF03095.15 RKP01744.1 - 1.2e-119 399.3 0.0 1.3e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein EST1_DNA_bind PF10373.9 RKP01744.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF4464 PF14713.6 RKP01745.1 - 1.4e-91 306.0 0.0 1.6e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) UIM PF02809.20 RKP01746.1 - 0.00081 19.1 2.6 0.0031 17.3 2.6 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif UBA_4 PF14555.6 RKP01746.1 - 0.0087 15.9 0.5 0.058 13.2 0.0 2.7 3 0 0 3 3 3 1 UBA-like domain Septin PF00735.18 RKP01747.1 - 9.3e-112 372.9 0.0 1.1e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RKP01747.1 - 5e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 RKP01747.1 - 3.6e-06 27.1 0.5 0.0089 16.1 0.1 2.5 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 RKP01747.1 - 2.3e-05 24.4 0.4 9.9e-05 22.3 0.2 2.1 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 RKP01747.1 - 0.00011 21.6 0.0 0.00033 20.1 0.0 1.9 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 RKP01747.1 - 0.00099 18.7 0.0 0.045 13.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 RKP01747.1 - 0.004 16.5 0.1 0.0095 15.3 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 RKP01747.1 - 0.0073 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 RKP01747.1 - 0.015 14.3 0.2 0.031 13.3 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 RKP01747.1 - 0.02 15.4 0.4 0.044 14.3 0.2 1.8 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 RKP01747.1 - 0.024 14.4 0.2 0.049 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 RKP01747.1 - 0.034 14.3 0.1 0.082 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKP01747.1 - 0.069 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Spore_IV_A PF09547.10 RKP01747.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_29 PF13555.6 RKP01747.1 - 0.083 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 RKP01747.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 RKP01747.1 - 0.11 12.8 0.5 0.39 11.0 0.5 2.3 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 RKP01747.1 - 0.16 11.8 0.9 3.8 7.2 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Ras PF00071.22 RKP01747.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Ras family Peptidase_M16_C PF05193.21 RKP01748.1 - 1.4e-37 129.5 0.0 2.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RKP01748.1 - 2.9e-26 92.2 0.0 5.7e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) HIT PF01230.23 RKP01749.1 - 6.2e-22 78.2 0.1 8.9e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 RKP01749.1 - 1.4e-08 35.2 0.0 2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Arv1 PF04161.13 RKP01750.1 - 5.2e-44 150.9 1.6 1.5e-39 136.3 0.0 2.1 1 1 1 2 2 2 2 Arv1-like family Pkinase PF00069.25 RKP01751.1 - 2.3e-34 119.0 0.0 2.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01751.1 - 5e-18 65.3 0.0 6.2e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01751.1 - 1e-06 28.3 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP01751.1 - 0.029 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP01751.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L39 PF00832.20 RKP01752.1 - 8.3e-22 76.6 13.6 9.4e-22 76.4 13.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein RabGAP-TBC PF00566.18 RKP01753.1 - 1.4e-48 165.4 0.0 1.7e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-C3HC4 PF00097.25 RKP01754.1 - 1.5e-06 28.0 14.8 2.2e-06 27.4 14.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKP01754.1 - 4.1e-06 26.6 11.1 7e-06 25.8 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP01754.1 - 2e-05 24.5 13.8 3.6e-05 23.6 13.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 RKP01754.1 - 3.3e-05 23.7 5.4 5.4e-05 23.0 5.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 RKP01754.1 - 3.5e-05 23.6 9.8 5.6e-05 22.9 9.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RKP01754.1 - 0.0001 22.6 12.8 0.00016 21.9 12.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKP01754.1 - 0.00017 21.4 14.2 0.00027 20.7 14.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP01754.1 - 0.001 19.1 10.3 0.0017 18.3 10.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RKP01754.1 - 0.065 12.9 6.5 0.13 11.9 6.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 RKP01754.1 - 0.081 13.2 10.8 0.64 10.4 10.8 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ribbon_3 PF13248.6 RKP01754.1 - 0.32 10.4 0.1 0.32 10.4 0.1 2.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-Nse PF11789.8 RKP01754.1 - 0.5 10.2 4.7 0.85 9.5 4.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 RKP01754.1 - 1.2 9.0 12.7 0.27 11.1 7.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L37e PF01907.19 RKP01754.1 - 1.3 9.2 7.3 1.6 8.9 6.1 1.8 1 1 0 1 1 1 0 Ribosomal protein L37e zf-C3HC4_5 PF17121.5 RKP01754.1 - 1.6 8.7 10.1 8.4 6.4 10.2 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKP01754.1 - 2.3 8.5 11.6 4.1 7.6 11.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4201 PF13870.6 RKP01754.1 - 4.5 7.0 10.7 1 9.1 1.2 2.9 1 1 0 3 3 3 0 Domain of unknown function (DUF4201) DUF5082 PF16888.5 RKP01754.1 - 6.3 7.1 6.4 17 5.7 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Leucyl-specific PF14795.6 RKP01754.1 - 7.6 6.7 7.0 0.45 10.6 0.8 2.2 3 0 0 3 3 3 0 Leucine-tRNA synthetase-specific domain NAP PF00956.18 RKP01755.1 - 6.4e-81 271.5 2.8 7.7e-81 271.2 2.8 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) She9_MDM33 PF05546.11 RKP01756.1 - 1.2e-46 159.0 7.4 1.7e-46 158.6 7.4 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family NYD-SP28 PF14772.6 RKP01756.1 - 0.028 14.5 0.5 0.65 10.1 0.1 2.3 2 0 0 2 2 2 0 Sperm tail GCOM2 PF15328.6 RKP01756.1 - 0.12 12.7 0.2 0.12 12.7 0.2 1.6 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 FAM153 PF15722.5 RKP01756.1 - 0.68 10.3 3.1 2.3 8.6 2.2 2.2 2 0 0 2 2 2 0 FAM153 family Baculo_PEP_C PF04513.12 RKP01756.1 - 0.95 9.5 5.0 2.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 RKP01757.1 - 1.7e-11 44.4 4.5 0.046 14.6 0.0 7.8 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01757.1 - 0.012 15.9 0.0 0.89 9.9 0.0 3.6 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Tim44 PF04280.15 RKP01758.1 - 6.4e-10 39.3 0.0 1.9e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 RKP01758.1 - 0.0036 16.4 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein L_lactis_ph-MCP PF06673.11 RKP01758.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Ribosomal_L32p PF01783.23 RKP01759.1 - 8.6e-06 25.9 6.8 9.1e-06 25.8 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family zf_C2H2_13 PF18508.1 RKP01759.1 - 0.12 12.0 2.7 0.17 11.5 2.7 1.3 1 0 0 1 1 1 0 Zinc finger domain zf-ribbon_3 PF13248.6 RKP01759.1 - 1.2 8.6 7.3 3.4 7.2 7.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Sec8_exocyst PF04048.14 RKP01760.1 - 1.7e-27 96.1 0.0 3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 RKP01760.1 - 8.4e-07 28.6 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Rab5-bind PF09311.11 RKP01761.1 - 0.0066 15.9 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Rabaptin-like protein DUF2418 PF10332.9 RKP01762.1 - 5.8e-18 65.2 0.0 9.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) FHIPEP PF00771.20 RKP01763.1 - 0.0071 14.9 0.0 0.0088 14.6 0.0 1.1 1 0 0 1 1 1 1 FHIPEP family TPR_5 PF12688.7 RKP01763.1 - 0.11 12.8 0.3 0.18 12.1 0.3 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat Pkinase PF00069.25 RKP01764.1 - 2.1e-65 220.7 0.0 2.9e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01764.1 - 1.3e-35 122.9 0.0 2.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 RKP01764.1 - 8.1e-22 77.1 8.3 4.9e-12 45.8 2.2 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 RKP01764.1 - 2.5e-18 65.7 21.4 6.4e-11 42.0 6.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 RKP01764.1 - 5.8e-10 39.7 3.5 1.5e-09 38.4 3.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_2 PF03107.16 RKP01764.1 - 0.00014 22.1 12.8 0.027 14.8 4.0 2.5 2 0 0 2 2 2 2 C1 domain C2 PF00168.30 RKP01764.1 - 0.00056 20.2 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain OrfB_Zn_ribbon PF07282.11 RKP01764.1 - 0.0031 17.4 3.0 0.0031 17.4 3.0 2.4 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Haspin_kinase PF12330.8 RKP01764.1 - 0.0042 16.1 0.4 0.0067 15.4 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKP01764.1 - 0.0062 15.9 0.0 0.022 14.1 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Uds1 PF15456.6 RKP01764.1 - 0.0096 16.1 14.0 0.041 14.0 0.7 2.7 3 0 0 3 3 2 2 Up-regulated During Septation PHD PF00628.29 RKP01764.1 - 0.3 11.0 17.7 1.1 9.2 3.4 2.5 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 RKP01764.1 - 0.55 9.9 13.6 0.19 11.4 3.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 RKP01764.1 - 1.2 9.2 15.0 0.27 11.2 3.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 RKP01764.1 - 1.5 8.9 17.3 0.19 11.8 4.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 RKP01764.1 - 7.2 6.7 6.7 3.6 7.6 1.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4381 PF14316.6 RKP01765.1 - 0.0029 17.9 0.4 0.0082 16.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF3318 PF11780.8 RKP01765.1 - 0.68 9.9 3.4 1.2 9.1 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) RNase_HII PF01351.18 RKP01766.1 - 4.3e-51 173.6 0.0 6.9e-51 172.9 0.0 1.3 1 1 0 1 1 1 1 Ribonuclease HII Pro_isomerase PF00160.21 RKP01767.1 - 6.8e-49 166.2 0.0 7.6e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2428 PF10350.9 RKP01768.1 - 3.9e-38 131.3 0.0 3.3e-36 125.0 0.0 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) RRN3 PF05327.11 RKP01768.1 - 0.11 11.0 15.0 0.16 10.4 14.1 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 RKP01768.1 - 0.19 9.9 18.3 0.28 9.3 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 RKP01768.1 - 0.38 9.7 0.8 0.69 8.8 0.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 RKP01768.1 - 0.66 8.2 16.6 1.1 7.4 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BT1 PF03092.16 RKP01768.1 - 0.68 8.1 2.5 3.8 5.6 0.3 2.3 2 0 0 2 2 2 0 BT1 family Cwf_Cwc_15 PF04889.12 RKP01768.1 - 1.3 8.7 28.7 2.9 7.6 28.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 RKP01768.1 - 1.6 6.7 32.7 3 5.8 32.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 RKP01768.1 - 1.9 7.8 16.9 3 7.1 16.9 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 RKP01768.1 - 2.8 7.3 18.9 4.7 6.6 18.9 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 RKP01768.1 - 4.2 6.0 7.8 7.1 5.3 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.9 RKP01768.1 - 4.5 6.3 39.7 7.4 5.6 39.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 RKP01768.1 - 5.2 6.3 32.3 11 5.2 32.3 1.4 1 0 0 1 1 1 0 NOA36 protein Mpp10 PF04006.12 RKP01768.1 - 5.4 5.3 14.9 8 4.8 14.9 1.1 1 0 0 1 1 1 0 Mpp10 protein IFT57 PF10498.9 RKP01768.1 - 7.6 5.4 7.5 12 4.7 7.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Plasmodium_Vir PF05795.11 RKP01769.1 - 0.003 17.0 0.2 0.0048 16.4 0.2 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Podoplanin PF05808.11 RKP01769.1 - 0.0035 17.5 5.9 0.0087 16.2 5.9 1.6 1 0 0 1 1 1 1 Podoplanin EssA PF10661.9 RKP01769.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SPX PF03105.19 RKP01769.1 - 0.1 12.5 2.4 0.14 12.0 2.4 1.3 1 0 0 1 1 1 0 SPX domain Adeno_E3_CR2 PF02439.15 RKP01769.1 - 0.21 11.4 7.8 0.58 10.0 7.8 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 RKP01769.1 - 0.88 9.8 5.6 12 6.2 5.6 2.6 1 1 0 1 1 1 0 Glycophorin A SOG2 PF10428.9 RKP01769.1 - 0.92 8.6 13.9 2 7.6 13.9 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM154 PF15102.6 RKP01769.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.6 1 1 1 2 2 2 0 TMEM154 protein family SKG6 PF08693.10 RKP01769.1 - 7.6 6.0 10.4 0.068 12.6 0.8 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Nup88 PF10168.9 RKP01770.1 - 0.017 13.0 0.0 0.026 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore component SRR1 PF07985.12 RKP01770.1 - 0.34 11.0 1.1 11 6.2 0.2 2.5 2 0 0 2 2 2 0 SRR1 HLH PF00010.26 RKP01771.1 - 3.7e-09 36.4 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4598 PF15370.6 RKP01772.1 - 0.00014 22.3 0.5 0.13 12.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) Tfb5 PF06331.12 RKP01773.1 - 3.4e-25 87.8 1.7 4.2e-25 87.5 1.7 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 60KD_IMP PF02096.20 RKP01774.1 - 1.1e-12 48.2 3.8 5.5e-12 45.9 0.0 2.5 3 0 0 3 3 3 2 60Kd inner membrane protein Pkinase PF00069.25 RKP01775.1 - 4.3e-67 226.3 0.0 5.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01775.1 - 6.4e-31 107.6 0.0 8.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKP01775.1 - 4.8e-05 22.5 0.0 6.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKP01775.1 - 0.00019 20.9 0.0 0.0017 17.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 RKP01775.1 - 0.00059 19.2 0.1 0.0022 17.4 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP01775.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 RKP01775.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 RKP01775.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RKP01775.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EMP24_GP25L PF01105.24 RKP01776.1 - 8.3e-34 117.1 0.0 9.5e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TSC22 PF01166.18 RKP01776.1 - 0.095 13.0 0.5 0.18 12.1 0.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family TBK1_ULD PF18396.1 RKP01776.1 - 0.14 12.1 0.7 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain G-alpha PF00503.20 RKP01777.1 - 8.1e-113 377.2 0.9 1e-112 376.9 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RKP01777.1 - 8.4e-17 61.2 2.1 1.6e-11 44.0 0.0 3.4 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKP01777.1 - 8e-05 22.1 0.2 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RKP01777.1 - 0.00025 21.3 0.6 0.39 10.9 0.1 2.7 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RKP01777.1 - 0.043 13.6 0.5 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMP_C2CD2L PF18696.1 RKP01777.1 - 0.091 12.6 0.2 0.83 9.5 0.0 2.3 3 0 0 3 3 3 0 Synaptotagmin-like, mitochondrial and lipid-binding domain MMR_HSR1 PF01926.23 RKP01777.1 - 0.15 12.2 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TPH PF13868.6 RKP01778.1 - 3.2e-61 206.8 127.1 3.2e-61 206.8 127.1 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DUF3138 PF11336.8 RKP01778.1 - 8.6 4.8 7.1 18 3.8 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CPL PF08144.11 RKP01779.1 - 8.5e-09 35.9 0.2 6.2e-07 29.9 0.0 3.4 3 1 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 RKP01779.1 - 1.3e-06 27.7 0.0 0.061 13.0 0.0 3.9 3 0 0 3 3 3 2 Pumilio-family RNA binding repeat Aminotran_1_2 PF00155.21 RKP01780.1 - 2.6e-55 188.1 0.0 2.8e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 RKP01780.1 - 0.00032 19.4 0.0 0.0006 18.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 RKP01780.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 RKP01780.1 - 0.042 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RKP01780.1 - 0.062 12.6 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family tRNA-synt_2b PF00587.25 RKP01781.1 - 1.3e-34 119.7 0.0 2.4e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 RKP01781.1 - 1.3e-18 67.2 3.1 1.3e-18 67.2 3.1 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Fibrillarin PF01269.17 RKP01782.1 - 6.6e-104 346.0 0.0 7.4e-104 345.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 RKP01782.1 - 7.5e-06 25.8 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 RKP01782.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 RKP01782.1 - 0.0071 16.5 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 RKP01782.1 - 0.038 13.6 0.0 0.08 12.6 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Frag1 PF10277.9 RKP01783.1 - 3.7e-33 114.9 6.9 3.7e-33 114.9 6.9 2.8 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 RKP01783.1 - 0.04 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Radial_spoke PF04712.12 RKP01784.1 - 1.6e-133 446.3 0.1 1.9e-133 446.0 0.1 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein PAS_4 PF08448.10 RKP01784.1 - 0.57 10.5 3.8 11 6.3 0.0 3.8 3 1 0 3 3 3 0 PAS fold Phage_GPO PF05929.11 RKP01785.1 - 7.3 6.1 13.5 5.8 6.5 0.2 2.9 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Ras PF00071.22 RKP01786.1 - 2.9e-58 196.1 0.0 3.2e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP01786.1 - 8.7e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP01786.1 - 1.7e-10 40.6 0.0 2.2e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RKP01786.1 - 0.00029 20.8 0.0 1.1 9.2 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 RKP01786.1 - 0.0006 19.4 0.0 0.0014 18.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RKP01786.1 - 0.0056 16.2 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 RKP01786.1 - 0.0064 16.6 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 RKP01786.1 - 0.019 15.0 0.1 0.057 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 RKP01786.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 RKP01786.1 - 0.22 11.3 1.3 2 8.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GCD14 PF08704.10 RKP01787.1 - 6.7e-83 278.1 0.1 7.8e-83 277.9 0.1 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 RKP01787.1 - 2.6e-07 30.6 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RKP01787.1 - 4e-06 26.7 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 RKP01787.1 - 9.9e-06 26.5 0.2 1.8e-05 25.7 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RKP01787.1 - 0.00069 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 RKP01787.1 - 0.0047 17.6 0.0 0.0077 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RKP01787.1 - 0.0093 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 RKP01787.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin RrnaAD PF00398.20 RKP01787.1 - 0.062 12.4 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 RKP01787.1 - 0.072 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 RKP01787.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NAD_Gly3P_dh_N PF01210.23 RKP01787.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7TMR-HDED PF07697.11 RKP01788.1 - 0.087 12.9 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 7TM-HD extracellular RF-1 PF00472.20 RKP01790.1 - 1e-21 77.0 0.3 1.7e-21 76.3 0.3 1.3 1 0 0 1 1 1 1 RF-1 domain UQ_con PF00179.26 RKP01791.1 - 1.2e-37 128.7 0.1 1.4e-37 128.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKP01791.1 - 0.0027 18.0 0.3 0.0041 17.4 0.3 1.5 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 RKP01791.1 - 0.0036 16.9 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 uDENN PF03456.18 RKP01792.1 - 9.8e-14 51.9 1.0 1.5e-13 51.3 1.0 1.3 1 0 0 1 1 1 1 uDENN domain DENN PF02141.21 RKP01792.1 - 1.6e-08 34.7 0.0 9.5e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 DENN (AEX-3) domain Med14 PF08638.11 RKP01793.1 - 2e-35 122.0 0.3 3.5e-35 121.2 0.3 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Hemocyanin_M PF00372.19 RKP01793.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Formyl_trans_N PF00551.19 RKP01794.1 - 7.4e-41 139.9 0.0 2.3e-40 138.3 0.0 1.7 1 1 0 1 1 1 1 Formyl transferase Pil1 PF13805.6 RKP01795.1 - 1.3e-25 90.4 0.9 1.7e-25 90.0 0.9 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 CoA_transf_3 PF02515.17 RKP01795.1 - 0.006 15.7 0.1 0.0083 15.3 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III NYD-SP28_assoc PF14775.6 RKP01795.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain Mito_carr PF00153.27 RKP01797.1 - 7e-44 147.7 0.6 6.4e-19 67.7 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein KdgT PF03812.13 RKP01797.1 - 0.043 13.1 2.3 0.035 13.4 0.9 1.5 1 1 0 1 1 1 0 2-keto-3-deoxygluconate permease DEC-1_N PF04625.13 RKP01797.1 - 2 7.4 7.4 0.19 10.7 1.5 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Zn_clus PF00172.18 RKP01798.1 - 3.9e-06 26.9 10.9 7.3e-06 26.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7tm_3 PF00003.22 RKP01799.1 - 9e-25 87.8 12.4 1.5e-24 87.1 12.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR SBP_bac_8 PF13416.6 RKP01799.1 - 3.8e-09 36.8 1.6 5e-08 33.1 1.4 2.3 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 RKP01799.1 - 1.6e-08 34.9 0.1 7e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein CENP-Q PF13094.6 RKP01800.1 - 0.044 14.0 9.1 0.28 11.4 0.4 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MAM33 PF02330.16 RKP01801.1 - 1.2e-44 152.8 1.3 1.4e-44 152.6 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein TatD_DNase PF01026.21 RKP01802.1 - 1.4e-36 126.2 0.0 1.9e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Pkinase PF00069.25 RKP01803.1 - 1e-41 143.1 0.0 1.1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01803.1 - 2.5e-23 82.7 0.0 2.9e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01803.1 - 1.4e-06 27.9 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP01803.1 - 1e-05 24.5 0.1 1.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKP01803.1 - 1.7e-05 24.3 0.4 2.2e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RKP01803.1 - 0.059 12.9 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 RKP01803.1 - 0.061 13.2 1.6 0.58 10.0 0.3 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 RKP01803.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Archease PF01951.16 RKP01803.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) Pkinase PF00069.25 RKP01804.1 - 6.4e-48 163.4 0.0 7.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01804.1 - 3.9e-20 72.2 0.0 5.2e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP01804.1 - 2.1e-08 33.8 0.2 3e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP01804.1 - 3.3e-08 33.2 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP01804.1 - 0.00042 20.3 0.7 0.00091 19.2 0.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKP01804.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 RKP01804.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M16 PF00675.20 RKP01805.1 - 1.5e-21 76.9 0.0 2.4e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RKP01805.1 - 1.1e-11 45.1 0.0 2.3e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain zf-C2H2_2 PF12756.7 RKP01806.1 - 3.9e-21 75.3 0.4 4e-19 68.8 1.3 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RKP01806.1 - 0.0043 17.3 0.1 0.0086 16.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 RKP01806.1 - 0.011 16.1 1.7 0.011 16.1 1.7 3.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP01806.1 - 0.023 15.5 10.7 0.18 12.7 0.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKP01806.1 - 0.47 10.3 1.6 6.5 6.6 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Tti2 PF10521.9 RKP01807.1 - 0.00033 20.3 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 Tti2 family DUF3437 PF11919.8 RKP01807.1 - 0.015 15.2 1.1 0.077 12.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) TPK_catalytic PF04263.16 RKP01808.1 - 1.3e-29 102.7 0.0 2.7e-29 101.6 0.0 1.5 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 RKP01808.1 - 1.2e-12 47.3 0.0 1.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain WD40 PF00400.32 RKP01809.1 - 1.1e-47 159.0 14.3 8.8e-08 32.7 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 RKP01809.1 - 2.8e-19 69.2 5.1 5.6e-19 68.2 5.1 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 RKP01809.1 - 5e-14 52.4 0.0 0.0014 18.8 0.0 5.3 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP01809.1 - 2.1e-05 23.7 0.2 0.12 11.3 0.0 4.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKP01809.1 - 0.0025 16.5 1.8 1.2 7.7 0.0 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RKP01809.1 - 0.015 14.6 0.0 0.81 8.9 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 RKP01809.1 - 0.021 14.8 0.5 5.4 7.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat dCMP_cyt_deam_2 PF08211.12 RKP01809.1 - 0.046 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region ASCH PF04266.14 RKP01809.1 - 0.24 12.0 0.1 1.5 9.5 0.1 2.3 3 0 0 3 3 3 0 ASCH domain SOBP PF15279.6 RKP01809.1 - 2.5 8.6 14.2 0.72 10.4 5.8 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein SNARE PF05739.19 RKP01810.1 - 8e-15 54.6 1.0 8e-15 54.6 1.0 2.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 RKP01810.1 - 2.5e-14 53.4 2.9 2.5e-14 53.4 2.9 1.4 2 0 0 2 2 2 1 Syntaxin SKA1 PF07160.12 RKP01810.1 - 0.00029 20.8 1.1 0.0004 20.3 1.1 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 KxDL PF10241.9 RKP01810.1 - 0.0059 16.8 0.8 0.0059 16.8 0.8 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein HemX PF04375.14 RKP01810.1 - 0.0093 15.3 1.7 0.012 14.9 1.7 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4795 PF16043.5 RKP01810.1 - 0.012 15.2 0.6 0.014 15.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Tweety PF04906.13 RKP01810.1 - 0.017 13.8 0.3 0.022 13.5 0.3 1.2 1 0 0 1 1 1 0 Tweety UPF0242 PF06785.11 RKP01810.1 - 0.031 14.4 2.6 0.058 13.5 2.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 RKP01810.1 - 0.035 13.7 1.5 0.046 13.3 1.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2368 PF10166.9 RKP01810.1 - 0.056 13.1 0.3 0.056 13.1 0.3 1.9 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DHR10 PF18595.1 RKP01810.1 - 0.056 13.5 3.8 0.6 10.2 1.4 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain V-SNARE PF05008.15 RKP01810.1 - 0.08 13.3 2.5 0.14 12.6 1.6 1.9 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.10 RKP01810.1 - 0.08 13.1 0.7 0.12 12.6 0.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 RKP01810.1 - 0.17 12.4 2.1 0.25 11.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 WXG100 PF06013.12 RKP01810.1 - 0.27 11.5 8.2 0.76 10.1 1.3 2.8 1 1 2 3 3 3 0 Proteins of 100 residues with WXG MCPsignal PF00015.21 RKP01810.1 - 4.7 7.0 8.5 1.4e+02 2.2 8.5 2.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SMAP PF15477.6 RKP01810.1 - 6.2 7.9 9.1 0.5 11.3 1.0 2.5 1 1 1 2 2 2 0 Small acidic protein family Rhomboid PF01694.22 RKP01811.1 - 3.1e-21 76.0 14.3 5.5e-21 75.1 14.3 1.3 1 0 0 1 1 1 1 Rhomboid family DUF2070 PF09843.9 RKP01811.1 - 0.053 11.8 2.8 0.064 11.6 2.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyt-b5 PF00173.28 RKP01812.1 - 7.7e-21 74.0 0.0 9.6e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AICARFT_IMPCHas PF01808.18 RKP01813.1 - 6.9e-86 288.4 0.7 8.8e-86 288.0 0.7 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 RKP01813.1 - 1.9e-14 53.6 0.0 3.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF3106 PF11304.8 RKP01814.1 - 1.2 9.6 17.9 0.9 10.0 0.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) DUF842 PF05811.13 RKP01814.1 - 2 8.1 17.1 0.5 10.1 0.1 4.6 3 2 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) BRE1 PF08647.11 RKP01814.1 - 9.8 6.3 9.1 0.93 9.6 1.2 3.1 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Yip1 PF04893.17 RKP01815.1 - 6e-08 32.6 1.0 7.3e-08 32.3 1.0 1.1 1 0 0 1 1 1 1 Yip1 domain WD40 PF00400.32 RKP01816.1 - 8.5e-22 77.1 6.6 5.3e-05 23.9 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01816.1 - 7.5e-15 55.0 0.0 0.003 17.8 0.0 5.2 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 RKP01816.1 - 0.012 15.5 0.2 7.5 6.6 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 RKP01816.1 - 0.083 11.8 0.0 33 3.3 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKP01816.1 - 0.11 11.2 0.1 0.31 9.6 0.1 1.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 INCENP_ARK-bind PF03941.15 RKP01817.1 - 3.9e-11 42.7 0.1 3.9e-11 42.7 0.1 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region PRA1 PF03208.19 RKP01818.1 - 1.9e-10 40.5 5.8 1.1e-09 38.1 5.8 1.9 1 1 0 1 1 1 1 PRA1 family protein Ribosomal_L44 PF00935.19 RKP01819.1 - 1.2e-35 121.8 11.4 1.7e-35 121.4 11.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 RKP01819.1 - 0.011 16.0 0.8 0.019 15.3 0.8 1.4 1 0 0 1 1 1 0 Cathelicidin RRM_1 PF00076.22 RKP01820.1 - 2.2e-09 37.0 0.0 3.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M_domain PF12938.7 RKP01820.1 - 0.26 11.1 1.6 13 5.4 0.2 2.5 2 0 0 2 2 2 0 M domain of GW182 Glyoxalase PF00903.25 RKP01821.1 - 0.0036 17.5 0.0 0.16 12.2 0.0 2.9 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sec23_trunk PF04811.15 RKP01822.1 - 0.065 12.8 0.5 0.63 9.6 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain NACHT PF05729.12 RKP01823.1 - 0.00095 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 RKP01823.1 - 0.0043 16.3 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 RKP01823.1 - 0.0051 16.5 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP01823.1 - 0.0068 16.8 0.2 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain PRK PF00485.18 RKP01823.1 - 0.0099 15.6 0.0 0.08 12.7 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 RKP01823.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 RKP01823.1 - 0.091 13.1 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RKP01823.1 - 0.093 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 RKP01823.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 RKP01823.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 RKP01823.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CoaE PF01121.20 RKP01823.1 - 0.15 11.7 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase TrwB_AAD_bind PF10412.9 RKP01823.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain HA2 PF04408.23 RKP01824.1 - 5.6e-24 84.5 0.0 2e-23 82.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RKP01824.1 - 6.9e-23 80.8 0.0 1.8e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RKP01824.1 - 2.8e-13 50.2 0.0 8e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 RKP01824.1 - 6.8e-10 39.2 0.1 1.4e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 RKP01824.1 - 2.6e-05 24.5 0.0 7.9e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 RKP01824.1 - 6e-05 22.9 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 RKP01824.1 - 0.00061 18.9 0.9 0.0016 17.6 0.9 1.9 1 1 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 RKP01824.1 - 0.0024 18.4 1.3 2.4 8.7 0.0 2.8 2 1 0 3 3 2 2 ABC transporter ATPase PF06745.13 RKP01824.1 - 0.0047 16.3 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.6 RKP01824.1 - 0.0055 16.4 7.8 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RKP01824.1 - 0.0072 16.7 0.0 0.0072 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 RKP01824.1 - 0.049 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 RKP01824.1 - 0.1 12.2 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 RKP01824.1 - 0.11 12.5 0.0 1 9.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 RKP01824.1 - 0.13 12.2 0.0 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding DUF2744 PF10910.8 RKP01824.1 - 0.13 12.2 0.3 2 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) NAT PF04768.13 RKP01825.1 - 3.7e-39 134.1 0.0 7.8e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 RKP01825.1 - 9.8e-29 100.6 0.1 4.2e-28 98.6 0.1 1.9 1 1 1 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 RKP01825.1 - 3.7e-26 91.9 0.2 8.6e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 RKP01825.1 - 2.2e-10 40.9 0.0 4.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GARS_C PF02843.16 RKP01825.1 - 0.038 14.3 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Thioredox_DsbH PF03190.15 RKP01826.1 - 2e-74 249.0 0.0 3.9e-74 248.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 RKP01826.1 - 3.9e-09 36.6 0.0 8.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 RKP01826.1 - 1.5e-06 27.7 1.6 0.004 16.4 0.1 2.5 2 0 0 2 2 2 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 RKP01826.1 - 0.012 15.2 3.3 2.8 7.4 0.2 3.1 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.6 RKP01826.1 - 0.016 15.6 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_88 PF07470.13 RKP01826.1 - 0.024 13.7 5.5 0.044 12.9 1.1 2.7 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 NPR2 PF06218.11 RKP01827.1 - 2e-93 313.6 0.4 7e-74 249.2 1.5 3.2 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Afi1 PF07792.12 RKP01827.1 - 0.093 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HTH_28 PF13518.6 RKP01827.1 - 0.13 12.4 0.2 21 5.4 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain DAHP_synth_1 PF00793.20 RKP01828.1 - 2.9e-94 315.0 0.0 4.6e-94 314.3 0.0 1.3 1 0 0 1 1 1 1 DAHP synthetase I family CENP-Q PF13094.6 RKP01829.1 - 0.061 13.5 9.7 0.11 12.7 9.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GPO PF05929.11 RKP01829.1 - 0.12 12.0 11.4 0.18 11.4 11.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF5610 PF18433.1 RKP01829.1 - 0.13 12.8 6.8 0.3 11.6 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) HHH_2 PF12826.7 RKP01829.1 - 0.18 11.9 2.4 1.5 9.0 2.4 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix motif TFIIA PF03153.13 RKP01829.1 - 0.4 10.6 13.2 0.59 10.1 13.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ACP_PD PF04336.12 RKP01829.1 - 1.1 9.7 5.8 1.9 8.9 4.8 1.8 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase DUF4239 PF14023.6 RKP01829.1 - 1.1 8.9 5.9 1.8 8.3 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ABC2_membrane PF01061.24 RKP01830.1 - 3.4e-34 118.1 14.7 3.4e-34 118.1 14.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 RKP01830.1 - 1.5e-26 93.6 0.0 2.2e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RKP01830.1 - 0.0077 16.1 0.0 3.4 7.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RKP01830.1 - 0.012 14.8 20.8 0.022 13.9 20.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein EGF PF00008.27 RKP01830.1 - 0.017 15.4 19.0 0.42 11.0 8.1 3.9 3 0 0 3 3 3 0 EGF-like domain AAA_25 PF13481.6 RKP01830.1 - 0.04 13.5 0.1 0.089 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RKP01830.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain hEGF PF12661.7 RKP01830.1 - 1.2 9.9 22.3 0.18 12.5 4.3 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF adh_short PF00106.25 RKP01831.1 - 1.5e-31 109.4 0.1 5e-31 107.7 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKP01831.1 - 2.2e-22 79.8 0.2 6.5e-22 78.2 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKP01831.1 - 4.4e-15 56.1 0.2 7.5e-15 55.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RKP01831.1 - 5.3e-05 22.8 0.1 0.00033 20.2 0.2 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 RKP01831.1 - 0.00092 18.7 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 RKP01831.1 - 0.0026 17.4 0.3 0.0039 16.8 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.8 RKP01831.1 - 0.043 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 RKP01831.1 - 0.16 11.3 0.1 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ATG_C PF09333.11 RKP01831.1 - 0.49 10.8 0.0 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Ank_2 PF12796.7 RKP01832.1 - 4.4e-18 65.7 13.3 1.4e-12 48.1 1.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKP01832.1 - 5.7e-14 52.0 4.1 0.00035 20.8 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RKP01832.1 - 1.8e-09 37.6 10.2 0.00095 19.5 0.7 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 RKP01832.1 - 2e-09 37.8 10.1 1.4e-05 25.5 0.3 4.6 2 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP01832.1 - 2.9e-09 36.4 7.4 0.078 13.6 0.2 5.4 5 0 0 5 5 5 3 Ankyrin repeat Peptidase_M24_C PF16188.5 RKP01832.1 - 0.064 13.3 0.2 0.22 11.6 0.2 2.0 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 LRR_6 PF13516.6 RKP01833.1 - 3.7e-13 48.4 16.0 5.2e-06 26.1 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 RKP01833.1 - 0.018 15.4 0.1 54 4.4 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP01833.1 - 0.019 14.7 0.3 20 5.0 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat GATase_5 PF13507.6 RKP01834.1 - 1.3e-77 260.4 0.0 2e-77 259.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 RKP01834.1 - 6.5e-44 149.8 4.1 2.7e-30 105.6 0.2 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 RKP01834.1 - 2.2e-23 82.4 0.0 4.8e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 RKP01834.1 - 4.2e-14 52.8 0.0 8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 RKP01834.1 - 0.0079 16.8 0.5 0.086 13.5 0.0 2.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain MCM PF00493.23 RKP01835.1 - 2.7e-99 330.8 0.0 5e-99 329.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RKP01835.1 - 1.7e-37 128.1 0.0 3.8e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKP01835.1 - 4.9e-25 87.8 2.6 5.2e-25 87.7 1.1 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 RKP01835.1 - 8.2e-14 52.1 0.0 2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 RKP01835.1 - 2.1e-10 41.1 1.1 2.1e-10 41.1 1.1 2.8 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 RKP01835.1 - 1.7e-07 30.8 0.1 2.6e-06 27.0 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RKP01835.1 - 2.3e-06 27.5 0.0 3.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKP01835.1 - 9.2e-06 25.7 0.0 2.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Ub-RnfH PF03658.14 RKP01835.1 - 0.027 14.8 0.0 0.12 12.7 0.0 2.2 1 0 0 1 1 1 0 RnfH family Ubiquitin Sigma54_activat PF00158.26 RKP01835.1 - 0.051 13.3 0.1 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 RKP01835.1 - 0.12 12.8 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF834 PF05754.14 RKP01835.1 - 9.8 6.3 10.9 2.7 8.1 5.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF834) ATP-synt_ab PF00006.25 RKP01836.1 - 4.9e-61 206.1 0.0 7.3e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 RKP01836.1 - 5e-22 78.2 1.9 9.8e-22 77.3 1.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NACHT PF05729.12 RKP01836.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 RKP01836.1 - 0.027 13.7 0.8 0.072 12.3 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 RKP01836.1 - 0.081 12.3 0.5 0.18 11.1 0.5 1.6 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 RKP01836.1 - 0.092 13.1 2.8 0.57 10.5 0.7 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RKP01836.1 - 0.1 13.0 0.9 0.27 11.6 0.3 2.1 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 RKP01836.1 - 0.15 12.3 0.2 0.33 11.2 0.2 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 RKP01836.1 - 0.15 12.5 0.0 2.9 8.3 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 RKP01836.1 - 0.18 11.7 0.7 0.56 10.1 0.7 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATP-synt_DE_N PF02823.16 RKP01837.1 - 1.3e-13 50.6 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain LAL_C2 PF18603.1 RKP01838.1 - 0.39 10.9 6.7 0.62 10.3 6.7 1.4 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Pkinase PF00069.25 RKP01839.1 - 3.5e-65 220.0 0.0 5.1e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01839.1 - 8e-29 100.7 0.0 3.9e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKP01839.1 - 7e-06 25.6 0.9 0.072 12.4 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 RKP01839.1 - 0.0046 16.3 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP01839.1 - 0.0091 15.9 0.4 1.6 8.6 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKP01839.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 RKP01839.1 - 0.3 10.0 0.0 0.49 9.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF1769 PF08588.10 RKP01840.1 - 1.1e-15 57.5 0.1 3e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Ras PF00071.22 RKP01841.1 - 1.5e-45 154.7 0.0 4.1e-45 153.3 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RKP01841.1 - 9.7e-16 58.1 0.0 1.6e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 RKP01841.1 - 2.8e-05 24.1 0.0 0.055 13.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 RKP01841.1 - 0.00024 20.6 0.0 0.0064 16.0 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKP01841.1 - 0.0044 16.6 0.0 0.0097 15.5 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EF-hand_13 PF17958.1 RKP01842.1 - 2e-07 30.7 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RKP01842.1 - 4.8e-06 26.9 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RKP01842.1 - 0.00068 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 RKP01842.1 - 0.0014 18.0 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RKP01842.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 RKP01842.1 - 0.055 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Sec5 PF15469.6 RKP01843.1 - 2.4e-39 135.1 0.0 3.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 RKP01843.1 - 0.0079 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Cwf_Cwc_15 PF04889.12 RKP01843.1 - 1.5 8.5 6.2 2.5 7.8 6.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DEAD PF00270.29 RKP01844.1 - 2.7e-51 173.8 0.0 4.4e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP01844.1 - 3.5e-24 85.3 0.0 8e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peripla_BP_3 PF13377.6 RKP01844.1 - 0.011 16.1 0.3 0.94 9.8 0.1 2.6 2 0 0 2 2 2 0 Periplasmic binding protein-like domain ResIII PF04851.15 RKP01844.1 - 0.012 15.7 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 RKP01846.1 - 0.02 14.7 7.7 0.026 14.3 7.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RKP01846.1 - 0.13 11.5 12.3 0.19 11.0 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 RKP01846.1 - 0.38 10.5 1.3 0.53 10.0 1.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF688 PF05097.12 RKP01846.1 - 0.41 9.8 1.3 0.54 9.4 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) RXT2_N PF08595.11 RKP01846.1 - 0.41 10.6 3.8 0.57 10.2 3.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 RKP01846.1 - 0.47 10.1 1.7 0.77 9.4 1.7 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 RKP01846.1 - 0.74 8.0 3.3 0.88 7.8 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 RKP01846.1 - 0.86 9.0 4.4 1.1 8.7 4.4 1.1 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 RKP01846.1 - 0.87 9.9 6.0 1.5 9.1 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RRN3 PF05327.11 RKP01846.1 - 3.9 5.9 4.0 4.8 5.6 4.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 RKP01846.1 - 4 7.9 19.9 8.8 6.8 19.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 RKP01846.1 - 5.1 6.6 5.2 6.8 6.2 5.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NADH-u_ox-rdase PF10785.9 RKP01847.1 - 2.3e-11 44.2 0.0 2.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Fasciclin PF02469.22 RKP01848.1 - 3.5e-20 72.5 0.1 1.2e-12 48.2 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Actin PF00022.19 RKP01849.1 - 1.3e-46 159.1 0.0 2.3e-44 151.6 0.0 2.8 1 1 0 1 1 1 1 Actin FtsA PF14450.6 RKP01849.1 - 0.0039 17.6 0.0 0.055 13.9 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 RKP01849.1 - 0.11 11.3 0.0 9.2 5.0 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein PilM_2 PF11104.8 RKP01849.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Dpy-30 PF05186.13 RKP01851.1 - 2.8e-15 55.7 0.1 5.3e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif T2SSG PF08334.11 RKP01851.1 - 0.028 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G DUF2797 PF10977.8 RKP01852.1 - 0.093 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RCDG1 PF15725.5 RKP01852.1 - 0.48 10.9 3.0 0.84 10.1 3.0 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein SH3_9 PF14604.6 RKP01853.1 - 1.8e-05 24.5 0.0 4.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01853.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.6 2 0 0 2 2 2 1 SH3 domain RasGEF PF00617.19 RKP01854.1 - 4.3e-53 180.1 0.2 6.8e-53 179.5 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RKP01854.1 - 4.5e-15 55.8 0.0 9.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif RBD PF02196.15 RKP01854.1 - 1.2e-14 54.2 0.1 1.4e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain ubiquitin PF00240.23 RKP01854.1 - 0.037 13.8 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family FERM_N PF09379.10 RKP01854.1 - 0.28 11.1 0.9 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 FERM N-terminal domain Leo1 PF04004.13 RKP01855.1 - 6.1e-33 114.0 0.0 1.4e-32 112.8 0.0 1.6 1 0 0 1 1 1 1 Leo1-like protein DUF755 PF05501.11 RKP01855.1 - 0.12 12.6 1.0 0.25 11.6 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Acid_PPase PF12689.7 RKP01856.1 - 8.1e-49 165.7 0.0 9.5e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 RKP01856.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Tctex-1 PF03645.13 RKP01857.1 - 2.5e-21 75.8 0.3 3.2e-21 75.5 0.3 1.1 1 0 0 1 1 1 1 Tctex-1 family Med26 PF08711.11 RKP01858.1 - 1e-08 35.1 0.1 3.8e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain UPF0561 PF10573.9 RKP01858.1 - 5.5 7.1 8.7 0.28 11.3 0.4 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0561 ORC4_C PF14629.6 RKP01859.1 - 1.4e-16 60.5 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 RKP01859.1 - 1.9e-11 44.7 0.6 1.9e-11 44.7 0.6 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP01859.1 - 9.3e-05 22.7 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 RKP01859.1 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 RKP01859.1 - 0.0096 15.3 0.0 0.024 14.1 0.0 1.6 1 1 0 1 1 1 1 Bacterial TniB protein T2SSE PF00437.20 RKP01859.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA12 PF10443.9 RKP01859.1 - 0.054 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein cobW PF02492.19 RKP01859.1 - 0.12 12.0 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF4910 PF16254.5 RKP01859.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Tom22 PF04281.13 RKP01860.1 - 1.7e-23 83.0 0.1 1.7e-23 82.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 MCR_alpha PF02249.17 RKP01860.1 - 0.0082 16.6 0.1 0.0094 16.4 0.1 1.2 1 0 0 1 1 1 1 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF4586 PF15239.6 RKP01861.1 - 1.5e-24 87.7 0.0 9.3e-24 85.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) LSM PF01423.22 RKP01862.1 - 1.1e-13 50.6 0.2 1.3e-13 50.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain FmiP_Thoc5 PF09766.9 RKP01864.1 - 1.1e-25 90.8 0.2 1.4e-25 90.4 0.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 GOLGA2L5 PF15070.6 RKP01864.1 - 0.0077 15.0 1.1 0.0077 15.0 1.1 1.5 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Spc29 PF17082.5 RKP01864.1 - 0.015 15.2 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 Phage_capsid PF05065.13 RKP01864.1 - 0.18 11.1 3.2 0.26 10.6 3.2 1.3 1 0 0 1 1 1 0 Phage capsid family ADIP PF11559.8 RKP01864.1 - 1.4 9.0 8.0 0.27 11.3 4.0 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 RKP01864.1 - 2.7 8.5 12.9 16 6.0 12.9 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DEAD_2 PF06733.15 RKP01865.1 - 1.3e-50 171.5 0.0 2.5e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 RKP01865.1 - 3.2e-49 167.4 0.0 6.7e-49 166.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 RKP01865.1 - 0.007 16.4 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 RKP01865.1 - 0.0087 15.5 0.2 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 RKP01865.1 - 0.098 12.4 0.6 2.5 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain NPL4 PF05021.15 RKP01866.1 - 1.7e-88 296.9 0.0 2.2e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 RKP01866.1 - 6.2e-58 195.1 0.0 9e-58 194.5 0.0 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 RKP01866.1 - 0.0035 17.8 0.0 0.0071 16.8 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 LPD26 PF18842.1 RKP01866.1 - 0.17 11.8 0.9 0.53 10.3 0.3 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 Arabino_trans_N PF17689.1 RKP01867.1 - 0.068 13.3 1.9 0.13 12.4 1.9 1.5 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain F-box PF00646.33 RKP01868.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 RKP01868.1 - 0.27 11.1 3.9 0.095 12.6 1.0 1.7 2 0 0 2 2 2 0 F-box-like RL10P_insert PF17777.1 RKP01869.1 - 2e-23 82.2 0.1 5.6e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RKP01869.1 - 1.9e-22 79.2 0.0 3.9e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 RKP01869.1 - 1.7e-15 57.3 3.8 1.7e-15 57.3 3.8 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.32 RKP01870.1 - 9e-23 80.1 14.9 8.6e-09 35.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 RKP01870.1 - 4.6e-07 28.9 8.5 0.0077 14.9 0.0 4.9 1 1 3 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RKP01870.1 - 6.7e-06 26.3 0.0 0.16 12.3 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RKP01870.1 - 0.00012 22.4 1.9 0.09 13.3 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain Nucleoporin_N PF08801.11 RKP01870.1 - 0.0018 17.1 0.0 0.94 8.1 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like PALB2_WD40 PF16756.5 RKP01870.1 - 0.0022 17.0 0.3 1.8 7.4 0.0 3.2 2 2 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain PHTB1_N PF14727.6 RKP01870.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PTHB1 N-terminus DUF3632 PF12311.8 RKP01871.1 - 0.055 13.9 1.7 0.06 13.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) Proteasome PF00227.26 RKP01872.1 - 6.4e-54 182.3 0.1 8.4e-54 181.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKP01872.1 - 2.8e-14 52.4 0.1 5.7e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RuvA_C PF07499.13 RKP01872.1 - 0.12 12.8 0.3 0.36 11.3 0.1 2.0 2 0 0 2 2 2 0 RuvA, C-terminal domain RNB PF00773.19 RKP01874.1 - 2.3e-39 135.6 0.0 6.7e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 RNB domain Homeobox_KN PF05920.11 RKP01875.1 - 2.6e-15 56.0 0.5 6.1e-15 54.8 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RKP01875.1 - 1.4e-05 24.8 0.2 3.2e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Homeodomain SPO11_like PF03533.14 RKP01875.1 - 0.0085 16.2 0.8 0.028 14.5 0.8 2.0 1 0 0 1 1 1 1 SPO11 homologue COX6A PF02046.15 RKP01876.1 - 8e-11 42.4 0.5 9.6e-11 42.2 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DNA_topoisoIV PF00521.20 RKP01877.1 - 3.3e-129 431.5 0.0 5.1e-129 430.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RKP01877.1 - 6.5e-47 159.0 0.4 6.5e-47 159.0 0.4 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RKP01877.1 - 1.4e-19 70.2 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 RKP01877.1 - 4.1e-12 46.6 0.0 9.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RKP01877.1 - 7.9e-08 32.5 0.0 3.1e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF4174 PF13778.6 RKP01877.1 - 0.091 13.2 0.1 0.28 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Glyco_hydro_65C PF03633.15 RKP01877.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain BBIP10 PF14777.6 RKP01877.1 - 0.12 12.0 0.3 0.31 10.6 0.3 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 DNA_gyraseB_C PF00986.21 RKP01877.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus UPF0029 PF01205.19 RKP01878.1 - 8.5e-29 100.0 0.0 1.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RGS12_usC PF16612.5 RKP01878.1 - 0.0014 19.1 0.4 0.0023 18.4 0.4 1.2 1 0 0 1 1 1 1 C-terminal unstructured region of RGS12 RWD PF05773.22 RKP01878.1 - 0.0015 18.8 0.2 0.42 10.9 0.2 2.4 1 1 0 1 1 1 1 RWD domain Arm PF00514.23 RKP01880.1 - 3.6e-19 68.1 24.6 8.6e-07 28.8 0.0 11.0 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKP01880.1 - 2.4e-08 34.2 6.1 1.6 9.2 0.0 7.2 4 2 3 7 7 7 3 HEAT repeats HEAT PF02985.22 RKP01880.1 - 0.002 18.2 22.1 0.96 9.9 0.2 7.9 9 0 0 9 9 9 2 HEAT repeat DUF3361 PF11841.8 RKP01880.1 - 0.005 16.8 4.0 0.0095 15.9 1.1 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 RKP01880.1 - 0.0072 16.5 0.8 1.6 9.0 0.1 3.0 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 RKP01880.1 - 0.0091 16.1 3.6 0.28 11.2 1.6 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF913 PF06025.12 RKP01880.1 - 0.028 13.4 0.2 0.84 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) HEAT_EZ PF13513.6 RKP01880.1 - 1.7 9.3 27.0 0.55 10.8 1.1 8.0 7 2 2 9 9 9 0 HEAT-like repeat Iso_dh PF00180.20 RKP01881.1 - 2.8e-91 306.3 0.0 3.7e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ago_PAZ PF18309.1 RKP01881.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Argonaute PAZ domain EF-hand_7 PF13499.6 RKP01882.1 - 5.8e-09 36.3 0.3 1.7e-08 34.8 0.3 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 RKP01882.1 - 1.6e-06 27.3 0.3 1.6e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 RKP01882.1 - 2.2e-06 26.9 0.0 3.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 RKP01882.1 - 0.00028 20.6 0.1 0.00086 19.1 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 RKP01882.1 - 0.00064 19.5 0.8 0.0025 17.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair RNase_P_Rpp14 PF01900.19 RKP01883.1 - 8e-23 80.6 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Cnd1 PF12717.7 RKP01884.1 - 5.3e-46 156.6 1.9 5.3e-43 146.9 0.1 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP01884.1 - 2.9e-07 30.8 4.1 0.047 14.1 0.0 4.9 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 RKP01884.1 - 1.8e-05 24.6 4.6 0.44 11.0 0.3 5.4 5 0 0 5 5 5 2 HEAT repeat Cnd3 PF12719.7 RKP01884.1 - 8.9e-05 21.8 1.0 0.00024 20.4 1.0 1.7 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 RKP01884.1 - 0.045 14.3 2.6 7.9 7.1 0.2 3.7 3 1 0 3 3 3 0 HEAT-like repeat Adaptin_N PF01602.20 RKP01884.1 - 0.15 10.6 4.6 0.78 8.2 0.3 3.1 3 0 0 3 3 3 0 Adaptin N terminal region DegS PF05384.11 RKP01884.1 - 0.88 9.0 5.1 0.25 10.8 1.3 1.9 2 0 0 2 2 2 0 Sensor protein DegS Ion_trans_2 PF07885.16 RKP01885.1 - 2.8e-06 27.2 11.9 0.0024 17.8 4.4 2.7 2 0 0 2 2 2 2 Ion channel 7tm_3 PF00003.22 RKP01885.1 - 0.0074 16.0 0.5 0.0074 16.0 0.5 2.4 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR MFS_1 PF07690.16 RKP01886.1 - 6.4e-20 71.4 21.6 2e-17 63.2 10.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 RKP01886.1 - 1.6e-12 47.4 8.7 5.3e-12 45.7 8.7 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Claudin_2 PF13903.6 RKP01887.1 - 0.27 11.0 1.3 0.45 10.2 1.3 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Septin PF00735.18 RKP01889.1 - 2.4e-122 407.6 0.1 2.4e-122 407.6 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 RKP01889.1 - 5.3e-10 39.4 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKP01889.1 - 1.4e-05 25.1 4.3 2.1e-05 24.5 0.5 2.8 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 RKP01889.1 - 2.4e-05 23.9 3.3 0.00015 21.3 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 RKP01889.1 - 0.00017 22.1 2.8 0.0018 18.8 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 RKP01889.1 - 0.00019 20.8 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 RKP01889.1 - 0.00052 20.3 0.0 0.0024 18.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF4075 PF13294.6 RKP01889.1 - 0.00053 20.1 4.9 0.42 10.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4075) Strep_SA_rep PF06696.11 RKP01889.1 - 0.0022 17.9 2.4 0.0069 16.3 2.4 1.9 1 0 0 1 1 1 1 Streptococcal surface antigen repeat AAA_16 PF13191.6 RKP01889.1 - 0.0057 17.0 0.0 0.015 15.7 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain Roc PF08477.13 RKP01889.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RKP01889.1 - 0.0066 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.22 RKP01889.1 - 0.0073 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 RKP01889.1 - 0.008 16.2 5.4 0.067 13.2 0.1 2.9 2 1 1 3 3 3 1 Dynamin family Mga PF05043.13 RKP01889.1 - 0.014 16.0 0.1 0.036 14.6 0.1 1.7 1 0 0 1 1 1 0 Mga helix-turn-helix domain AAA_24 PF13479.6 RKP01889.1 - 0.022 14.5 0.1 0.043 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 RKP01889.1 - 0.05 13.1 0.3 0.11 12.0 0.3 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Viral_helicase1 PF01443.18 RKP01889.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 RKP01889.1 - 0.081 12.1 0.5 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 RKP01889.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 RKP01889.1 - 0.088 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 RKP01889.1 - 0.098 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IIGP PF05049.13 RKP01889.1 - 0.11 11.6 0.1 0.11 11.6 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AP1AR PF15745.5 RKP01889.1 - 1.6 8.3 8.6 0.45 10.1 5.2 1.7 2 0 0 2 2 2 0 AP-1 complex-associated regulatory protein E1_DerP2_DerF2 PF02221.15 RKP01890.1 - 3.1e-22 79.4 0.0 3.6e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 RKP01890.1 - 6.2e-05 23.4 0.0 7.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ML-like domain Acyl-CoA_dh_1 PF00441.24 RKP01891.1 - 2e-25 89.7 5.7 3.1e-25 89.2 5.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 RKP01891.1 - 3.2e-19 68.9 0.0 6.1e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 RKP01891.1 - 1.6e-18 66.7 0.1 2.8e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RKP01891.1 - 6.2e-12 46.2 0.0 2.7e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 RKP01891.1 - 0.00013 22.2 0.2 0.00026 21.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CAP_N PF01213.19 RKP01892.1 - 0.097 12.1 2.2 0.19 11.2 2.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal VIR_N PF15912.5 RKP01892.1 - 0.56 9.8 1.7 0.98 9.0 1.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal AMP-binding PF00501.28 RKP01893.1 - 1.4e-66 224.9 0.0 1.9e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 RKP01893.1 - 5.3e-64 215.8 0.0 9.6e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 RKP01893.1 - 2.6e-15 56.1 0.1 2.5e-14 52.8 0.1 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 RKP01893.1 - 6.8e-13 48.8 0.0 1.7e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 RKP01893.1 - 3.2e-09 36.6 0.0 6.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 RKP01893.1 - 8.2e-08 33.1 0.2 8.9e-07 29.8 0.0 2.8 3 0 0 3 3 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 RKP01893.1 - 4.4e-05 22.6 0.0 8.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 RKP01893.1 - 0.01 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RKP01893.1 - 0.041 13.0 0.0 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CdiI_3 PF18616.1 RKP01893.1 - 0.047 13.6 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 CDI immunity proteins KR PF08659.10 RKP01893.1 - 0.062 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 KR domain AAA PF00004.29 RKP01894.1 - 2.1e-42 144.7 0.0 3.9e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RKP01894.1 - 3.5e-25 87.8 0.0 1e-24 86.3 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 RKP01894.1 - 6.7e-22 77.3 6.0 1.7e-21 76.0 6.0 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 RKP01894.1 - 4.8e-08 32.7 0.0 4e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 RKP01894.1 - 9.4e-06 26.1 0.1 0.00015 22.2 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 RKP01894.1 - 2.4e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 RKP01894.1 - 4.7e-05 23.2 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RKP01894.1 - 5.2e-05 22.6 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 RKP01894.1 - 6.6e-05 22.9 0.0 0.00036 20.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 RKP01894.1 - 8.1e-05 22.7 0.5 0.00056 20.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 RKP01894.1 - 0.00015 22.1 0.2 0.032 14.5 0.0 2.7 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.22 RKP01894.1 - 0.0002 21.7 0.1 0.0077 16.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 RKP01894.1 - 0.00062 19.0 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RKP01894.1 - 0.0029 17.8 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RKP01894.1 - 0.0031 17.3 0.8 0.013 15.3 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 RKP01894.1 - 0.0038 17.3 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 RKP01894.1 - 0.007 16.9 0.0 0.022 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RKP01894.1 - 0.0089 16.0 0.0 0.29 11.0 0.0 2.5 1 1 1 2 2 2 1 NACHT domain ATPase PF06745.13 RKP01894.1 - 0.016 14.6 0.1 4.8 6.5 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.6 RKP01894.1 - 0.016 14.8 0.1 0.23 11.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 RKP01894.1 - 0.017 15.6 0.0 0.063 13.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain USP8_dimer PF08969.11 RKP01894.1 - 0.022 14.9 8.8 0.061 13.5 8.0 2.1 2 0 0 2 2 2 0 USP8 dimerisation domain Mg_chelatase PF01078.21 RKP01894.1 - 0.032 13.6 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 RKP01894.1 - 0.046 12.8 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 RKP01894.1 - 0.049 13.1 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 RKP01894.1 - 0.055 13.2 0.0 0.52 10.0 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain NRBF2_MIT PF17169.4 RKP01894.1 - 0.068 13.4 0.3 0.15 12.3 0.3 1.5 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Tma16 PF11176.8 RKP01894.1 - 0.094 12.6 0.8 0.22 11.4 0.8 1.6 1 0 0 1 1 1 0 Translation machinery-associated protein 16 AAA_7 PF12775.7 RKP01894.1 - 0.095 12.2 0.0 0.39 10.2 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 RKP01894.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Torsin PF06309.11 RKP01894.1 - 0.18 11.9 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Torsin ATPase_2 PF01637.18 RKP01894.1 - 0.84 9.5 4.5 2.6 7.9 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Glyco_hydro_18 PF00704.28 RKP01895.1 - 1.2e-14 54.8 0.0 1.6e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.22 RKP01896.1 - 1.4e-66 225.2 0.0 1.7e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrophobin PF01185.18 RKP01899.1 - 1.5e-07 32.0 9.6 2.1e-07 31.5 9.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_29 PF08116.11 RKP01899.1 - 0.011 15.7 0.3 0.011 15.7 0.3 2.1 2 1 0 2 2 2 0 PhTx neurotoxin family FSA_C PF10479.9 RKP01901.1 - 1.7 6.7 18.1 1.7 6.7 18.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ASFV_J13L PF05568.11 RKP01901.1 - 1.7 8.3 22.9 2.3 7.9 0.1 2.0 1 1 1 2 2 2 0 African swine fever virus J13L protein SDA1 PF05285.12 RKP01901.1 - 6.4 6.1 10.6 7.3 5.9 10.6 1.0 1 0 0 1 1 1 0 SDA1 Ribosomal_S18 PF01084.20 RKP01902.1 - 7.7e-19 67.7 0.1 1.6e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Ctr PF04145.15 RKP01903.1 - 6.5e-20 72.3 6.0 4.3e-19 69.6 6.0 2.1 1 1 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 RKP01904.1 - 7.5e-10 39.0 11.8 7.5e-10 39.0 11.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 RKP01904.1 - 6.5e-06 26.3 0.0 0.00038 20.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 RKP01904.1 - 1.7e-05 25.4 0.1 0.0037 17.9 0.1 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain ApbA_C PF08546.11 RKP01905.1 - 1.6e-14 54.2 0.1 3.5e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 RKP01905.1 - 1.1e-09 38.1 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NOG1_N PF17835.1 RKP01909.1 - 7.3e-53 178.8 0.5 1.3e-52 178.0 0.5 1.4 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 RKP01909.1 - 2.1e-27 94.8 1.0 4e-27 93.9 1.0 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 RKP01909.1 - 1.3e-25 88.9 0.0 3.1e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 RKP01909.1 - 1.6e-18 66.9 0.0 3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP01909.1 - 7.3e-10 38.6 0.0 1.4e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RKP01909.1 - 0.00039 20.5 0.0 0.41 10.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 RKP01909.1 - 0.058 13.8 0.1 0.36 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain SRPRB PF09439.10 RKP01909.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RKP01909.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase TrkH PF02386.16 RKP01910.1 - 9e-52 176.1 8.7 3.1e-35 121.6 3.5 2.6 3 0 0 3 3 3 2 Cation transport protein FAM27 PF15832.5 RKP01910.1 - 0.13 12.8 4.7 0.24 12.0 4.7 1.3 1 0 0 1 1 1 0 FAM27 D and E protein family Aldose_epim PF01263.20 RKP01911.1 - 2.1e-39 135.7 0.0 3.7e-39 134.8 0.0 1.4 1 1 0 1 1 1 1 Aldose 1-epimerase DEC-1_N PF04625.13 RKP01912.1 - 0.025 13.6 3.6 0.026 13.5 3.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SH3_9 PF14604.6 RKP01913.1 - 4.1e-05 23.4 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP01913.1 - 0.0002 20.9 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Arrestin_C PF02752.22 RKP01913.1 - 0.00038 20.9 0.0 0.3 11.6 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RKP01913.1 - 0.023 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Rgp1 Arrestin_N PF00339.29 RKP01913.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain SAC3_GANP PF03399.16 RKP01914.1 - 6.3e-86 288.4 0.4 7.7e-86 288.1 0.4 1.0 1 0 0 1 1 1 1 SAC3/GANP family U-box PF04564.15 RKP01915.1 - 6.8e-25 87.0 0.0 1.2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 RKP01915.1 - 3.1e-13 48.7 7.7 1.7e-07 30.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 RKP01915.1 - 4.1e-13 48.5 8.3 4.6e-10 38.9 0.2 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP01915.1 - 8.3e-10 38.1 2.0 1.2e-06 28.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 RKP01915.1 - 2.3e-09 37.9 2.0 4.4e-09 37.0 2.0 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 RKP01915.1 - 8.9e-09 34.9 5.2 0.00021 20.9 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 RKP01915.1 - 2.2e-08 34.6 6.9 5.8e-07 30.1 1.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP01915.1 - 7.4e-06 26.1 1.9 7.4e-06 26.1 1.9 1.8 2 1 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKP01915.1 - 9.6e-06 26.0 9.4 0.00022 21.8 0.2 4.3 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKP01915.1 - 2.2e-05 24.7 2.2 2.2e-05 24.7 2.2 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKP01915.1 - 0.00085 19.8 3.3 2.3 9.1 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RKP01915.1 - 0.00099 18.9 3.9 0.014 15.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKP01915.1 - 0.0014 18.7 0.8 0.0077 16.3 0.1 2.6 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat MEIOC PF15189.6 RKP01915.1 - 0.0016 18.1 0.2 0.0026 17.4 0.2 1.4 1 0 0 1 1 1 1 Meiosis-specific coiled-coil domain-containing protein MEIOC TPR_17 PF13431.6 RKP01915.1 - 0.002 18.4 0.8 3.9 8.1 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP01915.1 - 0.0064 16.6 6.2 0.18 12.0 2.4 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKP01915.1 - 0.012 16.1 9.9 0.043 14.3 0.7 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKP01915.1 - 0.032 14.3 4.1 0.28 11.3 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKP01915.1 - 0.043 14.4 3.9 0.66 10.8 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Arginase PF00491.21 RKP01916.1 - 2.3e-74 250.4 0.0 2.6e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family POP1 PF06978.11 RKP01917.1 - 2.2e-30 106.2 18.8 1e-15 58.3 7.4 2.9 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 RKP01917.1 - 4.2e-19 68.7 0.0 1.4e-18 67.0 0.0 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF1690 PF07956.11 RKP01918.1 - 1.3e-11 45.1 0.3 1.4e-11 45.0 0.3 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 RKP01918.1 - 0.0082 16.2 0.1 0.013 15.5 0.1 1.4 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion AAA_6 PF12774.7 RKP01919.1 - 1e-155 517.7 0.0 6.1e-154 511.8 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKP01919.1 - 5e-126 421.0 3.1 5e-126 421.0 3.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKP01919.1 - 4.3e-104 348.0 0.0 1.6e-102 342.8 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKP01919.1 - 2.6e-95 318.7 0.0 6.2e-95 317.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKP01919.1 - 3.8e-82 274.7 0.0 1.3e-81 273.0 0.0 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKP01919.1 - 1.8e-63 213.4 0.0 2.8e-58 196.4 0.0 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 RKP01919.1 - 1.9e-51 175.1 1.7 4.2e-51 174.0 1.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RKP01919.1 - 8.4e-49 165.5 0.0 3e-48 163.7 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKP01919.1 - 1.1e-42 144.9 0.0 5.9e-42 142.5 0.0 2.4 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 RKP01919.1 - 1e-16 61.2 0.0 3.5e-16 59.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKP01919.1 - 1.1e-13 51.2 0.0 3.7e-13 49.5 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKP01919.1 - 1.5e-13 50.9 0.0 0.00051 20.1 0.0 5.7 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP01919.1 - 1.8e-07 31.5 2.0 0.22 11.8 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 RKP01919.1 - 2.3e-07 31.3 0.6 0.24 11.8 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 RKP01919.1 - 0.00028 21.5 0.8 0.046 14.3 0.0 4.2 4 0 0 4 4 3 1 AAA domain SH3BP5 PF05276.14 RKP01919.1 - 0.0097 15.7 0.3 0.0097 15.7 0.3 2.7 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) Fez1 PF06818.15 RKP01919.1 - 0.01 16.3 1.0 0.01 16.3 1.0 3.7 4 0 0 4 4 4 0 Fez1 AAA_30 PF13604.6 RKP01919.1 - 0.012 15.3 2.3 1.5 8.5 0.1 3.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 RKP01919.1 - 0.023 15.1 0.1 1.8 9.0 0.0 3.5 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 RKP01919.1 - 0.028 14.4 0.2 14 5.7 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RKP01919.1 - 0.055 13.6 1.0 32 4.7 0.0 4.4 5 0 0 5 5 3 0 AAA domain Sec34 PF04136.15 RKP01919.1 - 0.17 11.7 0.5 2.5 8.0 0.8 3.0 2 0 0 2 2 2 0 Sec34-like family Rad17 PF03215.15 RKP01919.1 - 0.22 11.4 0.8 19 5.1 0.0 3.5 3 0 0 3 3 3 0 Rad17 P-loop domain FAT PF02259.23 RKP01919.1 - 0.23 10.7 7.4 0.31 10.2 3.2 2.5 2 0 0 2 2 2 0 FAT domain AAA_16 PF13191.6 RKP01919.1 - 0.74 10.2 16.7 0.7 10.2 0.0 5.2 6 0 0 6 6 3 0 AAA ATPase domain DUF948 PF06103.11 RKP01919.1 - 1.2 9.5 9.3 0.23 11.7 0.2 4.0 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 RKP01919.1 - 1.2 9.2 16.7 1.2 9.2 2.7 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_11 PF13086.6 RKP01919.1 - 1.4 8.7 10.1 7.3 6.3 0.0 4.3 4 0 0 4 4 4 0 AAA domain LUC7 PF03194.15 RKP01919.1 - 1.8 8.1 5.3 17 5.0 0.1 2.7 2 0 0 2 2 2 0 LUC7 N_terminus XhlA PF10779.9 RKP01919.1 - 2.3 8.5 6.3 6.9 7.0 2.4 3.2 2 0 0 2 2 2 0 Haemolysin XhlA AAA_19 PF13245.6 RKP01919.1 - 3.4 8.0 5.8 34 4.8 0.0 3.9 4 0 0 4 4 3 0 AAA domain EzrA PF06160.12 RKP01919.1 - 6.3 4.8 10.3 0.058 11.6 1.1 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA WD40 PF00400.32 RKP01920.1 - 5.4e-05 23.9 10.0 0.044 14.7 0.0 5.7 4 1 1 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 RKP01920.1 - 0.00012 21.5 0.0 0.016 14.6 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 RKP01920.1 - 0.053 14.0 0.8 0.29 11.7 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain Pkinase PF00069.25 RKP01922.1 - 1.6e-69 234.2 0.0 2.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01922.1 - 7.8e-38 130.2 0.0 1.2e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 RKP01922.1 - 1.1e-31 108.8 0.1 1e-17 64.0 0.2 2.4 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 RKP01922.1 - 3.8e-05 22.7 0.1 5.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKP01922.1 - 0.00039 19.8 0.0 0.0016 17.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Aldedh PF00171.22 RKP01923.1 - 1.4e-100 337.0 0.5 1.6e-100 336.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 RKP01923.1 - 0.22 11.4 0.6 0.49 10.3 0.6 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) EF-hand_6 PF13405.6 RKP01925.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain DUF5582 PF17819.1 RKP01925.1 - 0.0084 16.6 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 RKP01925.1 - 0.0096 15.1 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5586) RIIa PF02197.17 RKP01925.1 - 0.031 13.9 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 RKP01925.1 - 0.058 13.1 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Dpy-30 motif Cwf_Cwc_15 PF04889.12 RKP01926.1 - 0.064 13.0 0.2 0.096 12.4 0.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4527 PF15030.6 RKP01927.1 - 4.3 6.7 7.4 5.3 6.4 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) RNA_Me_trans PF04252.13 RKP01928.1 - 4.2e-66 222.4 0.0 5e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase CRCB PF02537.15 RKP01930.1 - 2e-30 104.9 10.4 1.5e-14 54.1 0.2 3.2 3 0 0 3 3 3 3 CrcB-like protein, Camphor Resistance (CrcB) FMN_red PF03358.15 RKP01931.1 - 2.2e-05 24.2 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 RKP01931.1 - 0.021 15.0 0.1 0.14 12.3 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin MgsA_C PF12002.8 RKP01932.1 - 1.8e-56 190.6 0.0 2.9e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 RKP01932.1 - 5.1e-18 65.2 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 RKP01932.1 - 7.6e-11 42.6 0.0 2.5e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 RKP01932.1 - 3.6e-08 33.0 0.0 6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 RKP01932.1 - 9.6e-08 31.9 0.0 0.0019 17.9 0.0 2.5 1 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RKP01932.1 - 1.9e-06 28.3 0.1 1.6e-05 25.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RKP01932.1 - 8.1e-06 25.9 0.0 6.3e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RKP01932.1 - 9.7e-05 22.1 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 RKP01932.1 - 0.00045 20.5 0.0 0.0016 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKP01932.1 - 0.0027 17.9 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 RKP01932.1 - 0.0033 17.5 0.0 0.038 14.1 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 RKP01932.1 - 0.0051 17.3 0.0 0.0087 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RKP01932.1 - 0.025 15.0 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 RKP01932.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RKP01932.1 - 0.037 14.3 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKP01932.1 - 0.046 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RKP01932.1 - 0.057 13.9 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 RKP01932.1 - 0.068 13.2 0.0 9.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 RKP01932.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 RKP01932.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 RKP01932.1 - 0.11 12.8 0.1 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 RKP01932.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKP01932.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 RKP01932.1 - 0.19 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 RKP01932.1 - 0.21 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_1 PF00036.32 RKP01933.1 - 1.1e-12 46.5 11.8 3.5e-07 29.3 2.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 RKP01933.1 - 8.7e-11 40.9 9.7 1.2e-07 31.1 1.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RKP01933.1 - 4.3e-10 39.9 7.8 1.7e-06 28.4 0.5 2.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RKP01933.1 - 5.7e-10 38.9 5.0 0.00012 21.9 0.4 3.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RKP01933.1 - 4.8e-06 25.8 9.9 0.00012 21.4 2.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 RKP01933.1 - 0.0016 19.3 0.1 0.024 15.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain SurA_N_2 PF13623.6 RKP01933.1 - 0.0038 17.1 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 2 SurA N-terminal domain Syntaxin PF00804.25 RKP01933.1 - 0.049 13.3 0.1 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Syntaxin EF-hand_9 PF14658.6 RKP01933.1 - 0.054 13.8 1.3 0.7 10.3 0.1 2.6 3 1 0 3 3 3 0 EF-hand domain UPF0154 PF03672.13 RKP01933.1 - 0.13 12.3 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) CAP PF00188.26 RKP01935.1 - 1.7e-15 58.0 0.1 3.7e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4249 PF14054.6 RKP01935.1 - 0.0022 17.7 1.1 0.0028 17.4 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4249) Sel1 PF08238.12 RKP01936.1 - 1.9e-17 63.3 17.0 4.9e-05 23.9 0.0 5.3 5 1 0 5 5 5 4 Sel1 repeat Strabismus PF06638.11 RKP01936.1 - 0.22 10.1 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein FAD_binding_2 PF00890.24 RKP01937.1 - 3.8e-124 414.9 3.4 5e-124 414.6 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RKP01937.1 - 2.8e-43 146.9 3.9 4.4e-43 146.3 3.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 RKP01937.1 - 1.8e-05 24.1 1.3 0.035 13.2 2.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 RKP01937.1 - 0.00094 18.5 0.6 0.26 10.5 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 RKP01937.1 - 0.00097 18.5 0.7 0.0028 17.0 0.1 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKP01937.1 - 0.0026 17.1 0.2 0.005 16.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 RKP01937.1 - 0.035 13.7 0.8 0.07 12.7 0.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 RKP01937.1 - 0.37 9.4 1.3 1.3 7.6 0.7 2.2 3 0 0 3 3 3 0 HI0933-like protein Rogdi_lz PF10259.9 RKP01938.1 - 5.9e-18 65.3 0.0 7.2e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Hep_59 PF07052.11 RKP01939.1 - 5e-19 69.0 0.1 5e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 PIG-S PF10510.9 RKP01940.1 - 2e-06 26.9 0.1 2.3e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Mito_fiss_reg PF05308.11 RKP01940.1 - 8.8 6.3 9.2 11 6.0 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4201 PF13870.6 RKP01941.1 - 3.9e-32 111.4 13.7 3.9e-32 111.4 13.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) KxDL PF10241.9 RKP01941.1 - 0.0049 17.1 5.1 0.0087 16.3 3.7 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein Neur_chan_memb PF02932.16 RKP01941.1 - 1.1 9.2 3.3 1.2 9.1 2.6 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_C10 PF01640.17 RKP01941.1 - 2.5 8.4 4.7 4.5 7.6 1.2 2.1 1 1 1 2 2 2 0 Peptidase C10 family dsDNA_bind PF01984.20 RKP01942.1 - 3e-35 120.9 0.0 4e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Dor1 PF04124.12 RKP01943.1 - 6e-32 110.6 0.1 2.1e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 RKP01943.1 - 1.9e-06 27.9 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 RKP01943.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.5 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Mito_carr PF00153.27 RKP01944.1 - 7.6e-40 134.8 4.1 1e-14 54.2 0.2 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein MSP1b PF03429.13 RKP01944.1 - 0.071 11.2 0.4 0.098 10.7 0.4 1.1 1 0 0 1 1 1 0 Major surface protein 1B ELO PF01151.18 RKP01945.1 - 2.8e-55 187.6 9.6 3.1e-55 187.4 9.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UCH PF00443.29 RKP01946.1 - 5.6e-39 134.2 0.0 9.4e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 RKP01946.1 - 4e-08 33.0 0.2 1e-07 31.8 0.2 1.7 1 0 0 1 1 1 1 A repeated domain in UCH-protein UCH_1 PF13423.6 RKP01946.1 - 0.0042 16.7 0.1 0.65 9.5 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 RKP01947.1 - 4.3e-09 36.8 0.8 2.7e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKP01947.1 - 6e-09 36.3 6.0 0.0011 19.5 0.8 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RKP01947.1 - 7.2e-07 29.4 6.5 0.00011 22.4 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP01947.1 - 8.1e-06 25.8 6.5 0.00078 19.7 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 RKP01947.1 - 0.00082 19.2 0.1 0.013 15.3 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.30 RKP01947.1 - 0.0016 18.8 7.6 0.0025 18.2 0.1 4.0 3 1 1 4 4 4 1 Ankyrin repeat PCM1_C PF15717.5 RKP01947.1 - 0.14 10.8 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Med3 PF11593.8 RKP01947.1 - 0.61 9.2 4.5 0.81 8.8 4.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lipase_GDSL_2 PF13472.6 RKP01948.1 - 6.6e-21 75.5 0.1 1.1e-20 74.8 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKP01948.1 - 1.2e-11 45.0 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase bZIP_1 PF00170.21 RKP01949.1 - 0.00014 21.9 5.2 0.13 12.4 0.0 3.0 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 RKP01949.1 - 0.0003 20.8 1.6 0.68 10.1 0.1 2.5 2 0 0 2 2 2 2 Basic region leucine zipper TPR_MLP1_2 PF07926.12 RKP01949.1 - 0.004 17.2 4.8 0.011 15.9 4.8 1.7 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein MIP-T3_C PF17749.1 RKP01949.1 - 0.012 15.5 1.5 0.02 14.8 1.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region MAD PF05557.13 RKP01949.1 - 0.021 13.2 3.6 0.028 12.8 3.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3496 PF12001.8 RKP01949.1 - 0.024 15.0 4.9 0.039 14.3 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF4164 PF13747.6 RKP01949.1 - 0.05 13.9 1.5 0.12 12.7 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FH2 PF02181.23 RKP01949.1 - 0.055 12.6 2.0 0.075 12.1 2.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain HAP1_N PF04849.13 RKP01949.1 - 0.12 11.6 8.8 0.29 10.3 2.8 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF16 PF01519.16 RKP01949.1 - 0.14 12.6 3.5 0.13 12.8 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Filament PF00038.21 RKP01949.1 - 0.16 11.5 5.4 2.5 7.6 1.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein ATG16 PF08614.11 RKP01949.1 - 0.2 11.9 4.2 0.5 10.5 4.2 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 RKP01949.1 - 0.2 11.7 7.8 0.36 10.9 7.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 RKP01949.1 - 0.21 12.1 4.6 0.46 11.0 4.6 1.6 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Bacillus_HBL PF05791.11 RKP01949.1 - 0.27 11.0 0.9 0.4 10.5 0.9 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ERM PF00769.19 RKP01949.1 - 0.29 10.9 5.1 0.45 10.3 5.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family K-box PF01486.17 RKP01949.1 - 0.42 10.8 7.5 0.53 10.5 5.6 1.9 1 1 1 2 2 2 0 K-box region Cnn_1N PF07989.11 RKP01949.1 - 0.43 10.8 5.9 3.9 7.7 0.7 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 YscO PF07321.12 RKP01949.1 - 0.52 10.3 4.0 1.5 8.8 3.2 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO GAS PF13851.6 RKP01949.1 - 0.75 9.1 6.8 3 7.1 6.8 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 RKP01949.1 - 0.79 9.5 2.2 14 5.5 0.2 2.7 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.11 RKP01949.1 - 1.1 8.1 6.4 1.5 7.6 6.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 RKP01949.1 - 2.2 8.9 4.3 24 5.6 0.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 RKP01949.1 - 2.9 8.8 6.3 7.7 7.5 6.3 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Gcd10p PF04189.13 RKP01950.1 - 7.3e-62 209.2 0.0 9.1e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Bromodomain PF00439.25 RKP01951.1 - 9.1e-21 73.7 0.1 1.5e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.31 RKP01951.1 - 0.011 15.9 0.0 0.036 14.3 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain MIR PF02815.19 RKP01952.1 - 4.7e-12 46.1 0.3 1.1e-08 35.2 0.1 3.0 1 1 2 3 3 3 3 MIR domain DUF2087 PF09860.9 RKP01953.1 - 0.094 12.9 1.9 0.31 11.2 1.9 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF3584 PF12128.8 RKP01953.1 - 1 6.8 35.1 1.6 6.1 35.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prismane PF03063.20 RKP01953.1 - 4.9 5.7 7.6 7.2 5.2 7.6 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Y_phosphatase3 PF13350.6 RKP01954.1 - 9.8e-27 94.4 0.0 1.1e-26 94.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 RKP01954.1 - 1.8e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKP01954.1 - 1.3e-05 24.9 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 RKP01954.1 - 0.0015 17.6 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RKP01954.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RKP01954.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate EamA PF00892.20 RKP01955.1 - 2e-10 41.0 32.0 4.3e-07 30.2 2.1 2.6 2 1 1 3 3 3 2 EamA-like transporter family TMEM234 PF10639.9 RKP01955.1 - 0.00011 22.2 3.6 0.0012 18.9 0.4 2.4 2 0 0 2 2 2 2 Putative transmembrane family 234 Nuc_sug_transp PF04142.15 RKP01955.1 - 0.038 13.2 10.5 0.054 12.7 10.5 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter Alba PF01918.21 RKP01956.1 - 9.6e-15 54.2 0.3 1.3e-14 53.7 0.3 1.3 1 0 0 1 1 1 1 Alba Endonuclease_NS PF01223.23 RKP01957.1 - 1.3e-48 165.8 0.0 1.5e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 RKP01957.1 - 0.091 12.9 0.0 0.3 11.2 0.0 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease BOP1NT PF08145.12 RKP01958.1 - 9.2e-87 291.2 5.8 1.4e-86 290.7 5.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 RKP01958.1 - 8.6e-29 99.2 6.4 5.3e-08 33.4 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01958.1 - 8.3e-06 26.0 0.0 0.031 14.6 0.0 4.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IFT57 PF10498.9 RKP01958.1 - 0.11 11.4 8.6 0.17 10.8 8.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FANCL_C PF11793.8 RKP01959.1 - 1.6e-10 41.0 1.8 4e-10 39.7 1.8 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain WD-3 PF09765.9 RKP01959.1 - 2.5e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 WD-repeat region zf-RING_2 PF13639.6 RKP01959.1 - 0.74 10.2 10.9 4.3 7.8 10.9 2.3 1 1 0 1 1 1 0 Ring finger domain DUF2623 PF11115.8 RKP01960.1 - 0.032 14.3 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) KapB PF08810.10 RKP01960.1 - 0.24 11.6 1.0 1 9.6 0.0 2.5 3 0 0 3 3 3 0 Kinase associated protein B Pkinase PF00069.25 RKP01961.1 - 1.2e-67 228.0 0.0 1.5e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01961.1 - 3.6e-25 88.7 0.0 6.2e-25 88.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01961.1 - 6.5e-06 25.7 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RKP01961.1 - 0.00078 19.4 0.4 0.02 14.8 0.2 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKP01961.1 - 0.0075 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 RKP01961.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Scm3 PF10384.9 RKP01962.1 - 2.2e-09 36.9 5.1 3.1e-08 33.2 4.5 2.5 1 1 0 1 1 1 1 Centromere protein Scm3 rRNA_processing PF08524.11 RKP01963.1 - 1.5e-08 34.8 15.4 1.5e-08 34.8 15.4 2.8 1 1 1 2 2 2 2 rRNA processing Phage_Gp23 PF10669.9 RKP01963.1 - 3.1 8.1 6.3 6.2 7.2 6.3 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MS_channel PF00924.18 RKP01964.1 - 1.1e-19 70.9 0.1 1.3e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 RKP01964.1 - 2.5e-05 23.5 0.2 0.00013 21.2 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RKP01964.1 - 2.9e-05 23.6 0.0 9.7e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 RKP01964.1 - 0.00056 19.3 0.1 0.0026 17.2 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RKP01964.1 - 0.0013 19.1 0.2 0.0049 17.3 0.2 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RKP01964.1 - 0.045 13.6 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair CPP1-like PF11833.8 RKP01965.1 - 1.8 8.2 5.0 0.28 10.8 0.8 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pkinase PF00069.25 RKP01966.1 - 1.4e-66 224.6 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP01966.1 - 4.5e-40 137.6 0.0 5.6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP01966.1 - 3.5e-05 23.3 0.0 5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP01966.1 - 9.6e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 RKP01966.1 - 0.0076 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 RKP01966.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_10 PF13460.6 RKP01968.1 - 1e-10 41.8 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RKP01968.1 - 3.8e-09 36.4 0.0 5.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 RKP01968.1 - 4.6e-09 36.1 0.0 1.7e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RKP01968.1 - 3.8e-07 29.4 0.0 8.6e-07 28.2 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RKP01968.1 - 3.8e-06 26.2 0.0 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 RKP01968.1 - 0.00014 21.1 0.1 1.8 7.7 0.0 3.1 2 1 1 3 3 3 3 Male sterility protein Polysacc_synt_2 PF02719.15 RKP01968.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amidohydro_2 PF04909.14 RKP01969.1 - 2.3e-41 142.5 7.3 2.8e-41 142.2 7.3 1.1 1 0 0 1 1 1 1 Amidohydrolase CRAL_TRIO PF00650.20 RKP01970.1 - 2.8e-13 49.9 0.0 2.2e-08 34.0 0.0 3.1 3 0 0 3 3 3 2 CRAL/TRIO domain RRM_1 PF00076.22 RKP01971.1 - 5e-20 71.1 0.0 1.4e-10 40.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKP01971.1 - 0.00018 21.1 0.0 0.0021 17.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HsbA PF12296.8 RKP01972.1 - 4.1 7.8 11.1 0.21 12.0 1.8 2.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A HECT PF00632.25 RKP01973.1 - 3.9e-79 266.3 0.0 4.3e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3493 PF11998.8 RKP01973.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 DAGAT PF03982.13 RKP01974.1 - 4.8e-100 334.3 0.0 5.7e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LIM PF00412.22 RKP01975.1 - 3.9e-35 119.9 42.3 3.2e-10 40.1 3.7 8.1 6 2 2 8 8 8 6 LIM domain Cytochrome_P460 PF16694.5 RKP01975.1 - 4.3 7.7 0.0 4.3 7.7 0.0 3.9 4 0 0 4 4 4 0 Cytochrome P460 Mon1 PF03164.14 RKP01976.1 - 0.2 10.7 0.5 0.56 9.2 0.1 1.7 2 0 0 2 2 2 0 Trafficking protein Mon1 Lipase_GDSL_2 PF13472.6 RKP01977.1 - 6.5e-13 49.5 2.5 3.3e-12 47.1 1.3 2.5 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKP01977.1 - 9.2e-05 22.5 0.0 0.00021 21.3 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase NuDC PF16273.5 RKP01978.1 - 0.028 14.9 1.4 0.028 14.9 1.4 3.8 4 0 0 4 4 4 0 Nuclear distribution C domain RabGAP-TBC PF00566.18 RKP01979.1 - 1.8e-14 53.9 0.5 9.7e-14 51.5 0.5 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GSIII_N PF12437.8 RKP01981.1 - 1.6e-66 222.9 0.2 5.4e-66 221.2 0.1 1.9 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 RKP01981.1 - 2.2e-37 127.5 0.0 3.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 RKP01981.1 - 8.5e-22 77.6 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Phage_GPL PF05926.11 RKP01981.1 - 0.022 14.8 0.2 0.081 12.9 0.2 1.9 1 0 0 1 1 1 0 Phage head completion protein (GPL) TetR_C_33 PF13305.6 RKP01981.1 - 0.052 14.3 0.2 3.7 8.3 0.1 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IQ PF00612.27 RKP01982.1 - 0.0085 15.8 0.6 0.1 12.5 0.3 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif BLI1 PF17324.2 RKP01982.1 - 0.018 15.7 3.0 0.018 15.7 3.0 2.6 2 1 0 2 2 2 0 BLOC-1 interactor 1 Noelin-1 PF12308.8 RKP01982.1 - 0.038 14.0 1.2 0.038 14.0 1.2 3.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein DUF5481 PF17578.2 RKP01982.1 - 0.11 12.9 0.7 1 9.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5481) Nucleoporin_C PF03177.14 RKP01983.1 - 4.1e-36 124.9 0.0 7.8e-36 124.0 0.0 1.4 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal LIM PF00412.22 RKP01984.1 - 5.1e-26 90.7 39.1 7.6e-13 48.5 3.1 5.4 5 1 0 5 5 5 4 LIM domain RhoGAP PF00620.27 RKP01984.1 - 1.6e-22 80.0 0.2 4.5e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain BAG6 PF12057.8 RKP01984.1 - 0.19 11.4 0.8 0.48 10.1 0.4 1.8 2 0 0 2 2 2 0 BCL2-associated athanogene 6 WD40 PF00400.32 RKP01985.1 - 2.7e-19 69.2 4.0 2.9e-06 27.9 0.2 7.9 9 0 0 9 9 9 4 WD domain, G-beta repeat Utp21 PF04192.12 RKP01985.1 - 6.8e-18 65.0 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 RKP01985.1 - 7.4e-14 51.8 0.0 0.00051 20.3 0.0 5.9 4 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RKP01985.1 - 0.0073 14.9 0.2 0.024 13.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 RKP01985.1 - 0.012 15.5 0.2 2.1 8.4 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Mt_ATP-synt_B PF05405.14 RKP01986.1 - 3.2e-28 98.4 0.2 3.8e-28 98.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MCM_bind PF09739.9 RKP01988.1 - 1.7e-17 63.1 0.0 8.3e-14 50.9 0.0 3.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor VASt PF16016.5 RKP01989.1 - 3.2e-18 66.6 0.0 5.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 RKP01989.1 - 1.3e-16 60.5 0.0 2.1e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 GRAM domain WD40 PF00400.32 RKP01990.1 - 0.033 15.1 0.4 1 10.3 0.1 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01990.1 - 0.037 14.3 0.9 0.5 10.7 0.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_11 PF08241.12 RKP01991.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP01991.1 - 2.5e-16 60.2 0.0 5.4e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKP01991.1 - 1.1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RKP01991.1 - 1.6e-09 37.7 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP01991.1 - 3.7e-08 33.4 0.0 5.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP01991.1 - 1.2e-07 32.4 0.0 1.7e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RKP01991.1 - 0.00024 21.0 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 RKP01991.1 - 0.00068 19.2 0.0 0.0028 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 RKP01991.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 RKP01991.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 RKP01991.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 RKP01991.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 RKP01992.1 - 7.6e-22 77.8 0.0 1.9e-21 76.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP01992.1 - 3.3e-18 66.2 0.0 8.6e-18 64.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKP01992.1 - 4.1e-12 45.9 0.0 5.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RKP01992.1 - 3e-11 43.3 0.0 4.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP01992.1 - 4.3e-10 40.2 0.0 7.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP01992.1 - 3.8e-07 30.1 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 RKP01992.1 - 5.5e-07 29.6 0.0 9.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 RKP01992.1 - 0.004 16.7 0.0 0.033 13.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 RKP01992.1 - 0.036 13.2 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.6 RKP01993.1 - 3.1e-17 63.1 0.0 7.1e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Dala_Dala_lig_C PF07478.13 RKP01993.1 - 1e-16 61.1 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_31 PF13847.6 RKP01993.1 - 1.6e-12 47.5 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKP01993.1 - 1.7e-11 44.6 0.0 3.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP01993.1 - 1.4e-08 34.8 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKP01993.1 - 8.4e-07 28.6 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RKP01993.1 - 4.7e-06 27.3 0.0 9.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKP01993.1 - 6e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 RKP01993.1 - 0.00042 19.8 0.0 0.0011 18.4 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase ATPgrasp_Ter PF15632.6 RKP01993.1 - 0.018 14.8 0.0 0.17 11.6 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 RKP01993.1 - 0.047 13.8 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain RINGv PF12906.7 RKP01994.1 - 9.4e-16 57.7 9.0 1.7e-15 56.8 9.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 RKP01994.1 - 0.014 15.7 8.2 0.031 14.6 8.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 RKP01994.1 - 0.11 12.5 2.2 0.31 11.1 2.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prefoldin_2 PF01920.20 RKP01995.1 - 8.4e-17 61.1 0.7 1e-16 60.8 0.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 RKP01995.1 - 0.0081 15.9 8.6 0.44 10.3 1.7 2.3 2 0 0 2 2 2 2 Septum formation initiator FTA4 PF13093.6 RKP01995.1 - 0.0081 16.1 1.5 0.012 15.5 1.0 1.5 1 1 1 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 RKP01995.1 - 0.019 15.5 4.6 0.03 14.8 4.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 RKP01995.1 - 0.044 14.0 1.7 3.4 8.0 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 RKP01995.1 - 0.084 13.3 3.0 0.72 10.3 0.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) VSG_B PF13206.6 RKP01995.1 - 0.12 11.7 2.3 0.14 11.4 2.3 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1664 PF07889.12 RKP01995.1 - 0.12 12.5 1.1 1 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 RKP01995.1 - 0.27 11.8 6.3 0.56 10.8 0.5 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 RKP01995.1 - 0.32 11.1 3.9 4.6 7.4 1.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor HBS1_N PF08938.10 RKP01995.1 - 0.5 10.7 5.2 1.2 9.5 5.2 1.8 1 1 0 1 1 1 0 HBS1 N-terminus Muted PF14942.6 RKP01995.1 - 0.59 10.5 5.2 2.8 8.3 4.9 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF4407 PF14362.6 RKP01995.1 - 0.8 9.0 7.3 3.4 6.9 7.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mis14 PF08641.12 RKP01995.1 - 0.93 9.8 6.2 2.7 8.3 1.2 2.2 1 1 0 2 2 2 0 Kinetochore protein Mis14 like KfrA_N PF11740.8 RKP01995.1 - 0.98 10.1 13.7 0.46 11.2 10.7 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term PEP-utilisers_N PF05524.13 RKP01995.1 - 5.3 7.2 9.4 1.3 9.2 4.6 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal THOC7 PF05615.13 RKP01995.1 - 5.5 7.3 9.7 39 4.5 9.6 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 WD40 PF00400.32 RKP01996.1 - 1.3e-35 120.8 14.6 2.9e-07 31.1 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP01996.1 - 4.6e-10 39.7 0.1 0.00032 20.9 0.0 4.9 1 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP01996.1 - 0.00087 18.3 0.1 0.21 10.5 0.0 3.2 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RKP01996.1 - 0.2 10.9 0.0 2.2 7.5 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Putative_PNPOx PF01243.20 RKP01997.1 - 2e-22 79.2 0.0 3.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 RKP01997.1 - 8.1e-19 67.4 1.6 2.2e-18 66.0 1.6 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Complex1_LYR PF05347.15 RKP01998.1 - 5.9e-12 45.4 0.5 8.5e-12 44.9 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cytochrom_C1 PF02167.15 RKP01999.1 - 3.8e-93 311.2 0.0 4.4e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 RKP01999.1 - 0.0025 18.1 0.1 0.0056 17.0 0.1 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 RKP01999.1 - 0.015 16.4 0.3 0.036 15.2 0.3 1.7 1 1 0 1 1 1 0 Cytochrome c PPR_2 PF13041.6 RKP02000.1 - 0.15 12.3 0.1 26 5.1 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family DUF2423 PF10338.9 RKP02002.1 - 2.3e-12 46.9 2.8 2.3e-12 46.9 2.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 RKP02002.1 - 0.55 10.8 6.0 1.2 9.7 6.0 1.8 1 1 0 1 1 1 0 Learning-associated protein DEAD PF00270.29 RKP02003.1 - 3e-38 131.3 0.1 4.3e-37 127.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP02003.1 - 2.9e-25 88.8 0.1 1.6e-24 86.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP02003.1 - 1.9e-06 28.0 0.0 6.4e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ThiC_Rad_SAM PF01964.18 RKP02003.1 - 0.0087 14.9 0.0 0.18 10.5 0.0 2.1 2 0 0 2 2 2 1 Radical SAM ThiC family Herpes_ori_bp PF02399.15 RKP02003.1 - 0.02 13.0 0.1 0.29 9.1 0.0 2.0 2 0 0 2 2 2 0 Origin of replication binding protein GGDEF_2 PF17853.1 RKP02003.1 - 0.059 13.6 0.9 0.45 10.8 0.1 2.5 3 0 0 3 3 3 0 GGDEF-like domain AAA_22 PF13401.6 RKP02003.1 - 0.17 12.2 1.1 1.3 9.2 0.9 2.3 1 1 0 1 1 1 0 AAA domain Kp4 PF09044.10 RKP02004.1 - 5.3e-17 62.1 0.8 5.3e-17 62.1 0.8 1.7 2 0 0 2 2 2 1 Kp4 Kinesin PF00225.23 RKP02005.1 - 1.1e-117 392.8 0.0 1.6e-117 392.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP02005.1 - 1.2e-25 90.2 0.0 2.5e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 RKP02005.1 - 0.014 14.6 0.2 0.024 13.8 0.2 1.4 1 0 0 1 1 1 0 PIF1-like helicase Kinesin_assoc PF16183.5 RKP02005.1 - 0.043 14.0 7.9 0.11 12.6 7.9 1.7 1 0 0 1 1 1 0 Kinesin-associated AAA_22 PF13401.6 RKP02005.1 - 0.27 11.5 1.9 0.68 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain GLTT PF01744.20 RKP02006.1 - 0.66 9.8 3.9 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 GLTT repeat (6 copies) Cullin PF00888.22 RKP02007.1 - 5.8e-181 603.3 0.1 5.8e-181 603.3 0.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 RKP02007.1 - 3.3e-26 91.1 4.9 3.7e-26 90.9 3.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain TelA PF05816.11 RKP02007.1 - 0.037 13.1 2.1 0.047 12.7 0.1 2.2 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Patatin PF01734.22 RKP02007.1 - 0.088 13.0 0.2 0.8 9.8 0.0 2.6 2 2 0 2 2 2 0 Patatin-like phospholipase DUF2780 PF11075.8 RKP02007.1 - 0.31 11.2 2.6 7.7 6.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) PhoLip_ATPase_C PF16212.5 RKP02008.1 - 2.6e-60 204.3 12.4 2.6e-60 204.3 12.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKP02008.1 - 3.2e-16 58.8 0.5 3.2e-16 58.8 0.5 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RKP02008.1 - 1.9e-10 41.4 0.0 3.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP02008.1 - 1.8e-09 37.6 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKP02008.1 - 0.0021 17.9 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Erv26 PF04148.13 RKP02008.1 - 0.005 16.7 0.2 0.012 15.4 0.2 1.6 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 E1-E2_ATPase PF00122.20 RKP02008.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 0 E1-E2 ATPase His_Phos_1 PF00300.22 RKP02012.1 - 4.1e-23 82.1 9.8 5.5e-10 39.3 1.7 5.1 4 1 1 5 5 5 5 Histidine phosphatase superfamily (branch 1) Phage_holin_3_6 PF07332.11 RKP02014.1 - 0.0053 16.8 0.2 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2157 PF09925.9 RKP02014.1 - 0.056 13.2 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) LysE PF01810.18 RKP02014.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 LysE type translocator RFX_DNA_binding PF02257.15 RKP02015.1 - 5.3e-25 87.8 0.9 7.3e-25 87.4 0.1 1.7 2 0 0 2 2 2 1 RFX DNA-binding domain HD PF01966.22 RKP02015.1 - 0.12 12.6 0.3 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 HD domain DUF4707 PF15806.5 RKP02015.1 - 0.45 9.4 4.0 0.78 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4707) Peptidase_M1 PF01433.20 RKP02016.1 - 4.6e-32 111.4 0.0 6.1e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RKP02016.1 - 4.7e-26 91.1 0.0 8.9e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RKP02016.1 - 6.7e-24 85.1 0.0 9.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain zf-C2H2 PF00096.26 RKP02018.1 - 7.7e-15 54.4 8.8 5.3e-07 29.8 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02018.1 - 2.2e-09 37.4 7.6 0.00022 21.8 0.8 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP02018.1 - 9.1e-09 35.4 12.5 1.4e-08 34.8 2.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 RKP02018.1 - 0.00045 20.8 0.4 0.012 16.2 0.1 2.0 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 RKP02018.1 - 0.0013 18.9 1.7 0.14 12.5 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP02018.1 - 0.0032 17.8 0.8 0.14 12.5 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 RKP02018.1 - 0.012 15.9 0.3 0.073 13.4 0.3 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 RKP02018.1 - 0.015 16.0 1.2 0.017 15.8 1.2 1.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 RKP02018.1 - 0.015 15.4 0.8 2.5 8.2 0.1 2.0 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 RKP02018.1 - 0.033 13.9 11.1 0.4 10.5 1.2 2.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 RKP02018.1 - 0.041 13.9 0.4 0.041 13.9 0.4 3.1 2 2 0 2 2 2 0 C2H2-type zinc finger CCAP PF11105.8 RKP02018.1 - 0.081 12.9 0.5 0.081 12.9 0.5 1.0 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-LYAR PF08790.11 RKP02018.1 - 0.15 12.0 0.9 9.1 6.3 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Glyco_tranf_2_3 PF13641.6 RKP02019.1 - 4.7e-07 29.9 0.0 1.7e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RKP02019.1 - 5.9e-07 29.4 0.0 5.4e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Rad17 PF03215.15 RKP02021.1 - 1.3e-18 67.6 0.0 5.5e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 RKP02021.1 - 9e-07 29.4 0.0 3.8e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP02021.1 - 2.5e-06 28.0 3.6 3.8e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 RKP02021.1 - 0.0029 18.1 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 RKP02021.1 - 0.0031 17.8 0.0 0.0097 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 RKP02021.1 - 0.0038 17.5 0.1 0.038 14.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP02021.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKP02021.1 - 0.0051 17.1 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RKP02021.1 - 0.007 16.3 1.2 0.044 13.7 0.0 2.7 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.27 RKP02021.1 - 0.013 16.0 0.1 0.038 14.5 0.0 1.7 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.22 RKP02021.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 RKP02021.1 - 0.016 15.2 0.0 0.17 11.9 0.0 2.6 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RKP02021.1 - 0.017 14.7 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RKP02021.1 - 0.019 15.1 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 RKP02021.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase RuvB_N PF05496.12 RKP02021.1 - 0.037 13.8 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RKP02021.1 - 0.04 14.3 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 RKP02021.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase TsaE PF02367.17 RKP02021.1 - 0.11 12.6 0.0 0.84 9.6 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 RKP02021.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Sec7 PF01369.20 RKP02023.1 - 1.4e-09 37.9 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 RKP02023.1 - 0.26 11.3 0.0 0.46 10.5 0.0 1.3 1 0 0 1 1 1 0 PH domain Cnd2 PF05786.14 RKP02023.1 - 0.95 8.0 6.3 1.6 7.3 6.3 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 Cwf_Cwc_15 PF04889.12 RKP02023.1 - 1 9.1 11.9 2.4 7.8 11.9 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 RKP02023.1 - 5 5.2 5.4 7.6 4.6 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family SUI1 PF01253.22 RKP02024.1 - 1.1e-10 41.9 0.0 2.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.9 RKP02024.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Pre-PUA PF17832.1 RKP02024.1 - 0.23 12.2 1.5 1.7 9.4 0.1 2.6 2 1 0 2 2 2 0 Pre-PUA-like domain EF-hand_1 PF00036.32 RKP02025.1 - 2.1e-12 45.7 0.2 3.6e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 RKP02025.1 - 1.5e-11 43.3 0.4 3.3e-05 23.5 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain ZZ PF00569.17 RKP02025.1 - 2.1e-10 40.2 9.8 3.3e-10 39.6 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 RKP02025.1 - 4.4e-09 36.7 0.0 0.0014 19.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 RKP02025.1 - 5.9e-07 28.7 0.4 0.0043 16.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 RKP02025.1 - 1.3e-06 28.1 2.6 0.061 13.2 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain pair zf-B_box PF00643.24 RKP02025.1 - 2.1 8.5 9.6 3.9 7.7 9.6 1.4 1 0 0 1 1 1 0 B-box zinc finger Phage_holin_8 PF16931.5 RKP02026.1 - 0.18 11.8 1.3 0.37 10.8 1.3 1.6 1 0 0 1 1 1 0 Putative phage holin DEAD PF00270.29 RKP02027.1 - 3.7e-21 75.7 0.1 5.4e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP02027.1 - 2.1e-18 66.7 0.0 5e-15 55.8 0.1 2.1 1 1 1 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 RKP02027.1 - 1.8e-05 24.8 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 RKP02027.1 - 0.054 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 RKP02029.1 - 8.4e-06 26.2 0.0 2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RKP02029.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 RKP02029.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RKP02029.1 - 0.023 14.8 0.1 0.099 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RKP02029.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 RKP02029.1 - 0.053 13.5 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3138 PF11336.8 RKP02030.1 - 0.059 12.0 9.5 0.097 11.3 8.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4400 PF14348.6 RKP02030.1 - 0.076 12.5 0.2 0.21 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) OppC_N PF12911.7 RKP02030.1 - 0.48 10.4 1.9 0.68 10.0 0.3 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DEAD PF00270.29 RKP02031.1 - 8.6e-09 35.4 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RKP02031.1 - 2.9e-06 27.6 0.1 4.2e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKP02031.1 - 6.5e-05 23.3 0.1 9.2e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 RKP02031.1 - 0.018 15.6 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 RKP02031.1 - 0.04 13.9 0.1 0.25 11.3 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 RKP02031.1 - 0.072 12.9 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKP02031.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKP02031.1 - 0.14 11.4 0.1 2.9 7.1 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin UvrD-helicase PF00580.21 RKP02031.1 - 0.14 11.6 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HA2 PF04408.23 RKP02032.1 - 5.3e-10 39.5 0.1 8.2e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RKP02032.1 - 1.2e-07 32.0 0.1 2e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 RKP02034.1 - 1.8e-21 76.1 0.0 8.8e-07 29.0 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 RKP02034.1 - 1.1e-10 41.3 1.0 0.0017 18.2 0.0 3.4 3 0 0 3 3 3 3 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 RKP02034.1 - 4e-07 30.2 0.1 0.33 11.2 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Ribosomal_S21 PF01165.20 RKP02035.1 - 9.5e-07 28.5 2.6 1.6e-06 27.8 2.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 DUF1491 PF07372.12 RKP02035.1 - 0.066 13.6 4.1 0.19 12.1 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) PP2C PF00481.21 RKP02036.1 - 1.2e-62 211.9 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RKP02036.1 - 0.0042 17.0 0.9 0.016 15.1 0.8 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GRIP PF01465.20 RKP02037.1 - 1.5e-09 37.6 0.1 1.1e-08 34.8 0.1 2.4 1 1 0 1 1 1 1 GRIP domain Sds3 PF08598.11 RKP02038.1 - 2.1e-17 63.9 1.4 2.4e-17 63.7 1.4 1.1 1 0 0 1 1 1 1 Sds3-like DUF2315 PF10231.9 RKP02038.1 - 0.044 13.9 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Apoptogenic protein 1 MSP1_C PF07462.11 RKP02039.1 - 3.5 6.2 5.6 4.4 5.9 5.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RRM_1 PF00076.22 RKP02041.1 - 5.8e-24 83.7 0.1 2.3e-12 46.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP02041.1 - 8.7e-06 25.8 0.0 0.00038 20.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 RKP02041.1 - 0.045 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 RKP02041.1 - 0.16 11.8 0.0 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4874 PF16173.5 RKP02042.1 - 5.6e-11 42.4 0.0 7.9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 RKP02042.1 - 0.00023 21.1 0.1 0.0004 20.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) Methyltr_RsmB-F PF01189.17 RKP02043.1 - 1.6e-09 37.7 0.0 5.8e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F zf-UBR PF02207.20 RKP02044.1 - 3.1e-18 65.7 14.8 3.1e-18 65.7 14.8 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 RKP02044.1 - 6.1e-09 35.5 0.4 1.8e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Glyco_hydro_16 PF00722.21 RKP02045.1 - 1.6e-28 99.4 0.1 2.7e-28 98.6 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 TPR_1 PF00515.28 RKP02047.1 - 1.8e-08 33.9 2.3 0.061 13.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RKP02047.1 - 0.00027 20.8 11.2 1.1 9.6 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 RKP02047.1 - 0.00048 20.0 3.3 0.47 10.6 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 RKP02047.1 - 0.37 11.3 9.1 2.8 8.5 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2_jaz PF12171.8 RKP02048.1 - 1.4e-07 31.6 0.1 2.1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP02048.1 - 7.3e-06 26.2 0.1 1.1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 RKP02048.1 - 0.0056 16.7 0.2 0.0056 16.7 0.2 1.9 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 RKP02048.1 - 0.0063 16.9 0.4 0.01 16.2 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02048.1 - 0.014 16.2 0.1 0.026 15.4 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger SLX9 PF15341.6 RKP02048.1 - 0.022 15.1 2.3 0.04 14.3 2.3 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 zf-DBF PF07535.12 RKP02048.1 - 0.023 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger Ribosom_S12_S23 PF00164.25 RKP02049.1 - 2.1e-36 124.0 2.4 2.4e-36 123.8 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 RKP02049.1 - 0.0032 18.1 0.0 0.006 17.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S12 Nop52 PF05997.12 RKP02050.1 - 1.4e-42 146.0 0.3 1.9e-42 145.5 0.3 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SPX PF03105.19 RKP02050.1 - 3.3 7.5 12.6 5.1 6.9 12.6 1.2 1 0 0 1 1 1 0 SPX domain Ceramidase PF05875.12 RKP02051.1 - 2.5e-25 89.4 4.3 1.3e-14 54.3 1.9 2.0 1 1 1 2 2 2 2 Ceramidase UQ_con PF00179.26 RKP02052.1 - 1.6e-30 105.6 0.0 1.8e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKP02052.1 - 3.6e-06 26.7 0.0 4.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RKP02052.1 - 0.087 12.7 0.4 0.12 12.2 0.4 1.4 1 1 0 1 1 1 0 UEV domain Metallophos PF00149.28 RKP02054.1 - 1.3e-29 104.1 0.0 2.5e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 RKP02054.1 - 2.5e-18 66.2 0.0 4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.6 RKP02054.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 RKP02055.1 - 2.6e-09 36.5 6.6 0.00012 21.9 0.2 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02055.1 - 2.6e-09 36.5 6.7 7e-05 22.5 0.2 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKP02055.1 - 8.7e-09 34.9 4.9 1.7e-07 30.8 0.9 2.2 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 RKP02055.1 - 5.3e-05 23.1 3.1 0.011 15.9 0.7 2.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP02055.1 - 0.00042 20.4 0.1 0.00054 20.1 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKP02055.1 - 0.004 17.4 1.3 0.055 13.9 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKP02055.1 - 0.0055 17.4 1.0 0.17 12.8 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKP02055.1 - 0.022 15.0 4.3 0.11 12.8 4.3 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 RKP02055.1 - 0.093 13.4 6.1 0.12 13.0 0.2 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat ParcG PF10274.9 RKP02056.1 - 1.7e-78 263.0 0.0 1.9e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 RKP02056.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MMS19_C PF12460.8 RKP02056.1 - 0.087 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal UPF0139 PF03669.13 RKP02057.1 - 5.6e-11 42.2 0.1 7.1e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Ras PF00071.22 RKP02058.1 - 4.3e-57 192.2 0.0 5.1e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP02058.1 - 1.1e-35 122.4 0.0 1.5e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP02058.1 - 1.2e-15 57.4 0.0 1.4e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKP02058.1 - 8.7e-06 25.8 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RKP02058.1 - 0.00012 21.5 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RKP02058.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RKP02058.1 - 0.0029 18.0 0.0 0.0047 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 RKP02058.1 - 0.038 13.9 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SBP_bac_3 PF00497.20 RKP02058.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 GCP_N_terminal PF17681.1 RKP02059.1 - 4.8e-31 108.5 0.0 6.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RKP02059.1 - 5.5e-17 62.2 0.0 2.1e-16 60.3 0.0 1.9 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Mito_carr PF00153.27 RKP02060.1 - 2.1e-68 226.3 0.6 8.3e-25 86.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.15 RKP02060.1 - 0.047 13.8 0.5 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Chromate transporter DUF4726 PF15855.5 RKP02060.1 - 0.065 13.5 0.3 0.065 13.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Ribosomal_L28e PF01778.17 RKP02061.1 - 2e-17 64.0 0.3 2e-17 64.0 0.3 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family Lactamase_B_6 PF16661.5 RKP02062.1 - 1.2e-10 41.2 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain TFIIA PF03153.13 RKP02062.1 - 0.55 10.2 10.7 1.2 9.1 10.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyoxal_oxid_N PF07250.11 RKP02063.1 - 1.9e-24 86.2 0.0 1.9e-23 82.9 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 RKP02063.1 - 4.4e-17 62.1 0.0 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_3 PF13415.6 RKP02063.1 - 0.01 16.1 0.8 4.3 7.7 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Pkinase PF00069.25 RKP02064.1 - 6.8e-58 196.1 0.0 1.5e-52 178.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02064.1 - 3.8e-30 105.0 0.0 2.3e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKP02064.1 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP02064.1 - 0.012 15.6 0.2 0.38 10.6 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family PDEase_I PF00233.19 RKP02065.1 - 1.3e-61 208.4 0.0 1.5e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 RKP02065.1 - 0.0056 16.9 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 HD domain CH PF00307.31 RKP02066.1 - 1.2e-41 141.3 0.2 1.7e-22 79.7 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RKP02066.1 - 5.8e-08 32.5 0.0 1.8e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_1 PF00036.32 RKP02066.1 - 1.5e-07 30.5 0.0 5.5e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.10 RKP02066.1 - 6e-07 29.5 0.3 6.4e-06 26.2 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 RKP02066.1 - 1.3e-06 27.8 0.0 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 RKP02066.1 - 1.8e-06 28.3 0.8 9.6e-06 26.0 0.8 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RKP02066.1 - 0.00021 21.1 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 RKP02066.1 - 0.0013 18.1 0.1 0.003 17.0 0.1 1.6 1 0 0 1 1 1 1 EF hand Baculo_PEP_C PF04513.12 RKP02066.1 - 0.0037 17.3 4.3 0.0038 17.3 0.2 3.0 2 2 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 RKP02066.1 - 0.015 14.2 0.6 0.015 14.2 0.6 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Arfaptin PF06456.13 RKP02066.1 - 0.066 12.8 1.8 0.22 11.1 0.1 2.4 2 1 0 2 2 2 0 Arfaptin-like domain LUC7 PF03194.15 RKP02066.1 - 0.13 11.9 2.2 0.16 11.6 0.4 1.9 1 1 1 2 2 2 0 LUC7 N_terminus NPV_P10 PF05531.12 RKP02066.1 - 0.37 11.3 3.0 1.1 9.8 0.2 3.1 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 RKP02066.1 - 0.53 10.1 14.6 0.73 9.7 8.2 2.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Citrate_synt PF00285.21 RKP02067.1 - 2.8e-107 358.9 0.0 3.6e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 RKP02067.1 - 0.12 12.7 0.0 1.1 9.6 0.0 2.4 1 1 1 2 2 2 0 PAS fold SQS_PSY PF00494.19 RKP02068.1 - 1.2e-23 84.0 1.6 1.3e-23 83.9 1.6 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Zip PF02535.22 RKP02069.1 - 0.38 9.9 2.7 0.67 9.1 2.1 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Band_3_cyto PF07565.13 RKP02069.1 - 6 6.6 9.5 0.2 11.4 3.6 1.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PIP5K PF01504.18 RKP02070.1 - 7.1e-44 150.1 0.2 2.5e-35 122.0 0.3 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Aminotran_1_2 PF00155.21 RKP02071.1 - 1.1e-58 199.1 0.0 1.3e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RKP02071.1 - 5.5e-08 32.5 0.0 7.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RKP02071.1 - 0.00015 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RKP02071.1 - 0.0035 15.9 0.0 0.0053 15.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 RKP02071.1 - 0.037 13.3 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cauli_VI PF01693.16 RKP02072.1 - 6.1e-18 64.9 2.3 1.1e-17 64.0 2.3 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.24 RKP02072.1 - 1.1e-06 28.9 2.9 3.9e-05 23.9 0.7 2.9 2 1 0 2 2 2 1 RNase H Diphthamide_syn PF01866.17 RKP02073.1 - 1.4e-81 274.2 0.0 1.8e-81 273.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Rad4 PF03835.15 RKP02075.1 - 1.7e-07 31.0 0.1 2.1e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 RKP02075.1 - 4.1e-05 24.0 0.2 8.3e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily PAW PF04721.17 RKP02075.1 - 0.23 11.2 3.4 0.32 10.7 3.4 1.2 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW RMF PF04957.12 RKP02076.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Ribosome modulation factor Methyltransf_4 PF02390.17 RKP02077.1 - 5.8e-52 175.6 0.0 7.2e-52 175.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 RKP02077.1 - 0.0062 17.2 0.1 0.046 14.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 RKP02077.1 - 0.017 14.7 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 RKP02077.1 - 0.036 14.7 0.2 0.56 10.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain TIM PF00121.18 RKP02078.1 - 6.7e-89 297.4 0.0 7.6e-89 297.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 RKP02078.1 - 0.04 13.4 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 CutC family RabGAP-TBC PF00566.18 RKP02079.1 - 4e-29 101.8 0.6 4.9e-29 101.5 0.6 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3848 PF12959.7 RKP02079.1 - 0.0046 17.0 0.9 0.03 14.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3848) GCS PF03074.16 RKP02081.1 - 4.8e-151 503.3 0.0 5.9e-150 499.7 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase GCP_N_terminal PF17681.1 RKP02082.1 - 6e-07 29.4 0.0 2.4e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 RKP02082.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal FAA_hydro_N_2 PF18288.1 RKP02082.1 - 0.05 14.0 0.4 12 6.4 0.2 3.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DUF3486 PF11985.8 RKP02082.1 - 2.1 8.7 8.4 3.5 8.0 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3486) Peptidase_C78 PF07910.13 RKP02083.1 - 2.5e-33 115.4 0.0 4e-32 111.4 0.0 2.5 1 1 0 1 1 1 1 Peptidase family C78 EF-hand_4 PF12763.7 RKP02084.1 - 2.6e-14 53.0 0.0 2e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 RKP02084.1 - 1.3e-05 25.5 0.0 0.024 15.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 RKP02084.1 - 0.0015 18.0 0.1 2.8 7.7 0.0 3.5 3 0 0 3 3 3 1 EF hand TMF_TATA_bd PF12325.8 RKP02084.1 - 0.0036 17.5 18.4 0.23 11.7 1.3 2.2 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding EF-hand_6 PF13405.6 RKP02084.1 - 0.015 15.2 0.1 0.43 10.6 0.0 3.0 2 1 1 3 3 2 0 EF-hand domain EF-hand_8 PF13833.6 RKP02084.1 - 0.022 14.6 0.1 7.4 6.5 0.0 3.3 4 0 0 4 4 3 0 EF-hand domain pair Jnk-SapK_ap_N PF09744.9 RKP02084.1 - 0.022 15.0 15.7 0.022 15.0 15.7 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Laminin_I PF06008.14 RKP02084.1 - 0.034 13.9 22.3 0.1 12.3 9.5 2.1 1 1 1 2 2 2 0 Laminin Domain I DUF4763 PF15960.5 RKP02084.1 - 0.096 12.0 18.8 1.3 8.2 1.5 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 RKP02084.1 - 0.11 12.8 31.7 0.064 13.5 13.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 RKP02084.1 - 0.21 9.7 17.1 0.32 9.1 2.4 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 RKP02084.1 - 0.5 9.2 24.2 0.84 8.5 22.9 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 RKP02084.1 - 0.69 9.2 17.2 1 8.6 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 RKP02084.1 - 0.93 9.5 15.1 0.44 10.6 3.7 2.2 2 0 0 2 2 2 0 Laminin Domain II SKA2 PF16740.5 RKP02084.1 - 1.3 8.8 17.8 11 5.8 17.2 2.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Golgin_A5 PF09787.9 RKP02084.1 - 1.6 8.2 22.3 0.65 9.4 3.0 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 zf-C4H2 PF10146.9 RKP02084.1 - 1.8 8.8 11.2 3.1 8.1 11.2 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Fez1 PF06818.15 RKP02084.1 - 2.2 8.7 20.2 50 4.3 20.3 2.0 1 1 1 2 2 2 0 Fez1 Fib_alpha PF08702.10 RKP02084.1 - 2.2 8.5 11.4 61 3.8 10.4 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-K PF11802.8 RKP02084.1 - 2.4 7.7 19.1 9.7 5.7 6.0 2.1 1 1 1 2 2 2 0 Centromere-associated protein K Lebercilin PF15619.6 RKP02084.1 - 3.2 7.4 24.6 4.6 6.9 10.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-Q PF13094.6 RKP02084.1 - 3.6 7.7 23.6 0.26 11.5 17.2 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.19 RKP02084.1 - 3.7 7.3 25.0 4.5 7.0 25.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PilJ PF13675.6 RKP02084.1 - 3.9 7.5 15.8 82 3.3 15.8 2.2 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term FliJ PF02050.16 RKP02084.1 - 4.3 7.6 27.5 1.4 9.2 20.5 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein GAS PF13851.6 RKP02084.1 - 6.7 6.0 26.7 1 8.7 7.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mak10 PF04112.13 RKP02085.1 - 9.5e-06 25.2 0.5 0.03 13.8 0.0 2.7 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase GWT1 PF06423.12 RKP02086.1 - 2.9e-23 82.6 9.3 7.6e-23 81.3 4.5 3.1 2 2 0 2 2 2 1 GWT1 2TM PF13239.6 RKP02086.1 - 4.8 7.6 6.7 1 9.7 0.3 2.8 3 0 0 3 3 3 0 2TM domain DNA_methylase PF00145.17 RKP02087.1 - 2.2e-27 96.3 0.0 3.7e-27 95.5 0.0 1.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase AAA_28 PF13521.6 RKP02087.1 - 0.011 16.1 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 RKP02088.1 - 2.3e-49 167.5 0.3 2.9e-49 167.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 RKP02088.1 - 7e-13 47.8 0.6 7e-13 47.8 0.6 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal SH3_9 PF14604.6 RKP02089.1 - 5.6e-07 29.3 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP02089.1 - 0.00013 21.4 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKP02089.1 - 0.038 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain PEMT PF04191.13 RKP02090.1 - 5.9e-27 94.2 1.2 5.9e-27 94.2 1.2 1.8 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 RKP02090.1 - 0.0074 15.8 1.1 0.012 15.1 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 RKP02090.1 - 0.0099 15.9 0.6 0.039 13.9 0.5 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SBP_bac_5 PF00496.22 RKP02090.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Prefoldin_2 PF01920.20 RKP02091.1 - 2.3e-16 59.7 3.5 2.5e-16 59.5 3.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Lebercilin PF15619.6 RKP02091.1 - 0.009 15.7 5.4 0.55 9.9 0.3 2.0 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Spore_III_AB PF09548.10 RKP02091.1 - 0.027 14.6 1.6 0.19 11.9 0.1 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) SlyX PF04102.12 RKP02091.1 - 0.14 12.8 6.2 4.6 7.9 0.6 2.3 2 1 0 2 2 2 0 SlyX DUF724 PF05266.14 RKP02091.1 - 0.84 9.4 5.4 1.5 8.6 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Cpn60_TCP1 PF00118.24 RKP02092.1 - 3.2e-147 491.1 20.3 3.6e-147 490.9 20.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SCAB_CC PF16712.5 RKP02092.1 - 0.039 13.8 0.4 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein PI3Ka PF00613.20 RKP02093.1 - 5.7e-52 175.8 0.2 1e-51 175.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 RKP02093.1 - 2.3e-41 142.3 0.0 6.6e-26 91.6 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 RKP02093.1 - 1e-17 64.4 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Xpo1 PF08389.12 RKP02094.1 - 0.00045 20.3 0.0 0.36 10.9 0.0 2.8 3 0 0 3 3 3 2 Exportin 1-like protein CENP-B_dimeris PF09026.10 RKP02094.1 - 1.3 9.5 6.5 3.4 8.1 6.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WD40 PF00400.32 RKP02095.1 - 2.4e-54 180.1 24.6 6.9e-07 29.9 0.3 11.7 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 RKP02095.1 - 1.9e-18 66.7 0.0 3.4e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 RKP02095.1 - 1.6e-15 57.1 6.7 8.4e-06 26.0 0.1 7.2 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP02095.1 - 4.6e-07 28.9 5.6 0.13 10.9 0.1 5.5 4 1 2 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 RKP02095.1 - 0.00078 19.1 9.6 0.12 11.9 0.2 4.2 3 2 1 4 4 4 3 PQQ-like domain WD40_like PF17005.5 RKP02095.1 - 0.0011 18.4 0.0 0.0044 16.4 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain Nucleoporin_N PF08801.11 RKP02095.1 - 0.0016 17.3 0.1 7.2 5.2 0.0 4.1 2 1 2 4 4 4 2 Nup133 N terminal like UTP15_C PF09384.10 RKP02095.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal Ge1_WD40 PF16529.5 RKP02095.1 - 0.11 11.5 3.3 13 4.6 0.3 3.9 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Carboxyl_trans PF01039.22 RKP02096.1 - 1.2e-151 505.7 0.2 1.5e-151 505.4 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 RKP02096.1 - 0.0032 17.0 2.6 0.047 13.2 0.1 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) HSP70 PF00012.20 RKP02097.1 - 2.9e-260 864.6 5.1 3.4e-260 864.4 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKP02097.1 - 2.7e-15 56.0 0.2 3.6e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 RKP02097.1 - 0.00074 19.3 0.0 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 RKP02097.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.11 RKP02097.1 - 0.083 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 StbA protein RNA_GG_bind PF10258.9 RKP02097.1 - 0.098 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 PHAX RNA-binding domain Torus PF16131.5 RKP02098.1 - 5.9e-27 94.5 0.0 8.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 RKP02098.1 - 8.3e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 RKP02098.1 - 0.012 15.6 1.1 0.021 14.9 1.1 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 RKP02098.1 - 0.077 12.9 1.6 0.13 12.2 1.6 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PsbQ PF05757.11 RKP02099.1 - 1.5 8.5 3.4 1.9 8.2 2.5 1.6 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) PRIMA1 PF16101.5 RKP02099.1 - 3.9 7.5 6.8 1.6 8.8 1.5 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 peroxidase PF00141.23 RKP02100.1 - 2.3e-46 158.4 0.0 3.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Glyco_hydro_26 PF02156.15 RKP02101.1 - 1.1e-08 34.9 1.5 1e-06 28.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyl hydrolase family 26 DUF1180 PF06679.12 RKP02101.1 - 0.25 11.7 2.3 0.49 10.8 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3040 PF11239.8 RKP02101.1 - 0.29 11.4 0.9 0.5 10.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Laminin_EGF PF00053.24 RKP02103.1 - 0.0031 17.6 15.3 0.0031 17.6 15.3 5.2 5 1 0 5 5 5 1 Laminin EGF domain Furin-like_2 PF15913.5 RKP02103.1 - 0.064 13.4 0.0 0.064 13.4 0.0 4.0 4 0 0 4 4 4 0 Furin-like repeat, cysteine-rich CENP-B_dimeris PF09026.10 RKP02103.1 - 0.63 10.5 11.4 0.11 12.9 6.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 RKP02103.1 - 2 6.4 10.9 3.1 5.8 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 RKP02103.1 - 2.3 8.1 4.3 4.3 7.2 4.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 RKP02103.1 - 3.9 7.1 4.4 42 3.8 1.2 2.7 2 1 1 3 3 3 0 FAM176 family Abhydrolase_3 PF07859.13 RKP02104.1 - 7.8e-42 143.5 1.4 4.5e-41 141.0 1.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RKP02104.1 - 1.9e-12 46.7 0.0 3.3e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 RKP02104.1 - 0.091 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PROCN PF08083.11 RKP02105.1 - 2.1e-222 738.1 7.0 3.6e-222 737.3 7.0 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 RKP02105.1 - 8.2e-119 395.3 1.2 1.8e-117 390.9 1.2 2.3 1 1 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 RKP02105.1 - 1.1e-85 285.2 3.5 2.8e-85 283.8 3.5 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 RKP02105.1 - 3e-82 274.3 2.3 3e-82 274.3 2.3 2.1 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 RKP02105.1 - 4.9e-71 237.0 0.0 1.1e-70 235.9 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 RKP02105.1 - 6.9e-46 154.5 0.3 2e-45 153.0 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 RKP02105.1 - 2.6e-41 140.4 0.0 6.3e-41 139.1 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain Abhydrolase_3 PF07859.13 RKP02106.1 - 9.6e-46 156.3 2.8 1.2e-44 152.7 2.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RKP02106.1 - 1.3e-11 44.0 0.0 2.8e-11 42.9 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 RKP02106.1 - 6.9e-08 32.0 0.1 1.2e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 RKP02106.1 - 1.6e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) COesterase PF00135.28 RKP02106.1 - 0.00023 20.2 0.1 0.0006 18.8 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 RKP02106.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold KTI12 PF08433.10 RKP02107.1 - 3.8e-69 233.2 0.0 4.3e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 RKP02107.1 - 1.6e-09 38.1 0.2 3.1e-09 37.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain Ribosomal_L15e PF00827.17 RKP02108.1 - 2.3e-91 304.7 5.9 2.6e-91 304.5 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ints3 PF10189.9 RKP02109.1 - 2.8e-36 124.9 0.0 5.4e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 Integrator complex subunit 3 UNC-50 PF05216.13 RKP02110.1 - 1.4e-63 214.4 6.6 1.6e-63 214.3 6.6 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1129 PF06570.11 RKP02110.1 - 0.088 12.3 0.1 0.11 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) PMI_typeI PF01238.21 RKP02112.1 - 2.1e-105 353.0 0.0 2.3e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I CTP_transf_like PF01467.26 RKP02113.1 - 3.1e-30 105.2 0.1 4.2e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF3752 PF12572.8 RKP02115.1 - 9.7e-06 26.2 2.2 9.7e-06 26.2 2.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3752) K_channel_TID PF07941.11 RKP02115.1 - 0.048 14.1 19.4 0.53 10.8 6.4 2.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NUDIX PF00293.28 RKP02116.1 - 1.8e-15 57.1 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2b PF00587.25 RKP02117.1 - 1.3e-31 110.0 0.0 2.2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RKP02117.1 - 5e-08 33.0 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain M_domain PF12938.7 RKP02118.1 - 1.1 9.0 4.7 1.3 8.8 4.7 1.1 1 0 0 1 1 1 0 M domain of GW182 Sel1 PF08238.12 RKP02119.1 - 2.7e-50 167.7 37.8 4.8e-09 36.6 0.3 8.2 8 0 0 8 8 8 7 Sel1 repeat TPR_5 PF12688.7 RKP02119.1 - 0.015 15.5 0.3 0.14 12.4 0.0 2.6 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_6 PF13174.6 RKP02119.1 - 0.39 11.4 16.4 21 6.1 0.2 6.8 6 2 1 7 7 7 0 Tetratricopeptide repeat Cyclin_N PF00134.23 RKP02121.1 - 1.3e-12 47.6 0.1 1.4e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Focadhesin PF11229.8 RKP02121.1 - 0.002 16.4 0.0 0.0022 16.3 0.0 1.1 1 0 0 1 1 1 1 Focadhesin FERM_M PF00373.18 RKP02122.1 - 5.5e-12 46.1 0.0 8.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 FERM central domain ANAPC1 PF12859.7 RKP02123.1 - 0.0041 17.7 0.0 0.015 15.8 0.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 CSN8_PSD8_EIF3K PF10075.9 RKP02124.1 - 2.9e-26 92.2 0.0 5e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 RKP02124.1 - 2.1e-06 27.4 1.3 2.7e-06 27.0 1.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family SasG_E PF17041.5 RKP02125.1 - 0.027 14.5 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 E domain NFACT-R_1 PF05670.13 RKP02126.1 - 7.9e-37 126.2 0.0 1.4e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Phage_Mu_F PF04233.14 RKP02126.1 - 0.0057 17.4 2.6 0.0089 16.8 2.6 1.4 1 0 0 1 1 1 1 Phage Mu protein F like protein Prominin PF05478.11 RKP02126.1 - 0.032 12.2 1.4 0.035 12.1 1.4 1.0 1 0 0 1 1 1 0 Prominin DUF3027 PF11228.8 RKP02126.1 - 0.09 12.8 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF719 PF05334.13 RKP02126.1 - 0.18 12.0 3.9 0.3 11.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF4337 PF14235.6 RKP02126.1 - 0.64 10.1 4.5 0.53 10.4 3.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 RKP02127.1 - 2 8.5 10.7 2.8 8.0 10.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PIEZO PF15917.5 RKP02127.1 - 3.9 6.9 6.5 5.6 6.4 6.5 1.3 1 0 0 1 1 1 0 Piezo Tetraspanin PF00335.20 RKP02128.1 - 1.1e-27 97.3 10.3 1.3e-27 97.0 10.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Spore_YhaL PF14147.6 RKP02128.1 - 0.15 11.8 0.1 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL DUF2569 PF10754.9 RKP02128.1 - 0.98 9.9 5.8 1.2 9.6 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) FHA PF00498.26 RKP02129.1 - 3.8e-10 40.0 0.0 8.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Adeno_knob PF00541.17 RKP02129.1 - 0.086 12.6 0.4 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) FIT1_2 PF17357.2 RKP02129.1 - 0.27 11.3 8.0 2.2 8.4 1.6 2.5 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 Radial_spoke PF04712.12 RKP02130.1 - 2.2e-11 43.4 0.0 4.4e-06 25.9 0.0 2.7 2 2 1 3 3 3 2 Radial spokehead-like protein EI24 PF07264.11 RKP02131.1 - 5.4e-26 91.9 15.0 7.6e-26 91.4 15.0 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) G-gamma PF00631.22 RKP02132.1 - 9.7e-12 44.7 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain Nup192 PF11894.8 RKP02133.1 - 6.6e-113 378.3 0.0 3.4e-62 210.2 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 RKP02133.1 - 0.12 10.3 0.0 1.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin subcomplex protein binding to Pom34 DUF1266 PF06889.11 RKP02133.1 - 0.17 11.9 1.5 0.46 10.5 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) HABP4_PAI-RBP1 PF04774.15 RKP02134.1 - 5.6e-09 36.8 3.9 5.6e-09 36.8 3.9 2.7 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family Acyl-CoA_dh_M PF02770.19 RKP02135.1 - 8.3e-17 61.2 0.1 1.5e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 RKP02135.1 - 2e-08 34.0 1.1 3.7e-08 33.1 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 RKP02135.1 - 3.5e-06 27.3 0.1 3.5e-06 27.3 0.1 2.6 2 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Iso_dh PF00180.20 RKP02137.1 - 2.5e-77 260.4 0.0 2.9e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHFR_2 PF06442.11 RKP02137.1 - 0.15 11.9 0.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 R67 dihydrofolate reductase RhoGAP PF00620.27 RKP02138.1 - 8.5e-26 90.6 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Ribosomal_L7Ae PF01248.26 RKP02139.1 - 2e-22 78.7 0.0 2.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 RKP02139.1 - 0.045 13.9 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase JUPITER PF17054.5 RKP02140.1 - 0.00037 20.1 1.3 0.71 9.3 0.1 2.7 1 1 2 3 3 3 2 Microtubule-Associated protein Jupiter RNase_PH PF01138.21 RKP02142.1 - 8.1e-13 49.0 0.4 1.5e-12 48.2 0.4 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DNA_pol_D_N PF18018.1 RKP02143.1 - 7.2e-38 129.6 0.0 1.1e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 RKP02143.1 - 8.1e-31 107.0 0.0 1.8e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Adap_comp_sub PF00928.21 RKP02145.1 - 2.5e-90 302.5 0.0 3.1e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RKP02145.1 - 2.5e-11 43.7 0.3 4.5e-11 42.9 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 RKP02145.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DPPIV_N PF00930.21 RKP02145.1 - 0.052 12.3 0.1 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mon1 PF03164.14 RKP02145.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 BSD PF03909.17 RKP02146.1 - 2.9e-08 33.6 0.2 5.2e-08 32.8 0.2 1.4 1 0 0 1 1 1 1 BSD domain DUF1282 PF06930.12 RKP02147.1 - 0.034 13.9 3.9 0.048 13.4 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Pkinase PF00069.25 RKP02148.1 - 9.4e-47 159.6 0.0 1.1e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02148.1 - 8e-22 77.8 0.0 8.2e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKP02148.1 - 8.3e-05 22.6 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RKP02148.1 - 0.00032 20.1 0.0 0.00069 19.0 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP02148.1 - 0.0054 16.1 0.1 0.019 14.3 0.1 1.7 1 1 0 1 1 1 1 Kinase-like EcKinase PF02958.20 RKP02148.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 RKP02148.1 - 0.036 12.9 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 RKP02148.1 - 0.069 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkr1 PF08636.10 RKP02149.1 - 3.8e-18 65.4 0.0 5e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 PAT1 PF09770.9 RKP02150.1 - 4.8e-62 210.4 8.3 1.7e-47 162.3 0.0 5.3 5 0 0 5 5 5 5 Topoisomerase II-associated protein PAT1 MMR_HSR1_Xtn PF16897.5 RKP02151.1 - 4.2e-40 136.0 0.1 6.7e-40 135.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 RKP02151.1 - 2.4e-21 75.9 0.0 4.5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 RKP02151.1 - 1.3e-20 73.2 0.0 2.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 RKP02151.1 - 2.2e-11 43.5 0.0 4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RKP02151.1 - 2.2e-06 27.8 0.1 0.068 13.2 0.1 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 RKP02151.1 - 0.0038 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 RKP02151.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RKP02151.1 - 0.12 12.3 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase MPC PF03650.13 RKP02152.1 - 2e-42 143.8 0.3 2.4e-42 143.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 RKP02152.1 - 0.048 13.7 0.1 0.061 13.4 0.1 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange HEAT PF02985.22 RKP02153.1 - 1.5e-13 49.7 0.5 0.0096 16.1 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 RKP02153.1 - 6.8e-11 42.4 13.9 4e-07 30.4 0.1 5.7 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 RKP02153.1 - 5.6e-09 36.3 7.2 1.7e-06 28.3 0.1 4.2 3 1 1 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 RKP02153.1 - 3.1e-08 34.1 0.0 0.00071 20.1 0.0 2.9 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 RKP02153.1 - 7.3e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 CLASP N terminal IFRD PF05004.13 RKP02153.1 - 0.00014 21.1 0.6 3 6.9 0.0 4.1 3 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 RKP02153.1 - 0.00025 20.9 0.2 0.76 9.7 0.1 2.6 1 1 1 2 2 2 2 UME (NUC010) domain MMS19_C PF12460.8 RKP02153.1 - 0.013 14.6 5.3 3.6 6.6 0.7 3.6 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 RKP02153.1 - 0.1 11.1 0.2 1 7.8 0.0 2.3 2 1 1 3 3 3 0 Adaptin N terminal region Arm PF00514.23 RKP02153.1 - 0.11 12.6 4.3 1.6 8.9 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PAP1 PF08601.10 RKP02154.1 - 0.15 11.7 4.5 0.25 11.0 4.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Hydrophobin PF01185.18 RKP02155.1 - 8e-06 26.4 8.3 1.1e-05 25.9 8.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 RKP02156.1 - 8.5e-08 32.7 7.8 1.3e-07 32.2 7.8 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 RKP02157.1 - 5.7e-09 36.5 10.1 8.5e-09 35.9 10.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin VKOR PF07884.14 RKP02157.1 - 0.063 13.5 0.5 0.069 13.3 0.5 1.2 1 1 0 1 1 1 0 Vitamin K epoxide reductase family Peptidase_S8 PF00082.22 RKP02159.1 - 6.4e-35 120.8 13.1 1.4e-34 119.7 13.1 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 RKP02159.1 - 0.0094 16.6 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pkinase PF00069.25 RKP02160.1 - 1.1e-21 77.4 0.0 2.2e-14 53.5 0.0 3.2 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02160.1 - 5.9e-18 65.1 0.0 3.3e-12 46.3 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 RKP02160.1 - 4e-05 23.7 2.3 4e-05 23.7 2.3 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RKP02160.1 - 0.0017 17.7 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP02160.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2458 PF10454.9 RKP02161.1 - 8.5e-05 22.3 0.3 8.5e-05 22.3 0.3 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 RKP02161.1 - 0.00029 20.5 0.1 0.00051 19.7 0.1 1.3 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein tRNA_lig_CPD PF08302.11 RKP02161.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain SfLAP PF11139.8 RKP02161.1 - 0.17 11.3 0.1 0.17 11.3 0.1 2.0 3 0 0 3 3 3 0 Sap, sulfolipid-1-addressing protein Chorion_2 PF03964.15 RKP02161.1 - 4.1 8.3 20.2 0.34 11.7 1.7 3.5 3 1 1 4 4 4 0 Chorion family 2 Actin PF00022.19 RKP02162.1 - 6.8e-44 150.1 0.0 9.5e-27 93.6 0.0 2.2 2 0 0 2 2 2 2 Actin DUF3040 PF11239.8 RKP02162.1 - 0.0082 16.4 1.6 0.22 11.8 0.6 3.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) HMG_box PF00505.19 RKP02163.1 - 1.6e-10 41.2 0.2 7.8e-06 26.2 0.1 2.1 1 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 RKP02163.1 - 2.1e-06 28.2 0.0 7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 HMG-box domain RGI_lyase PF18370.1 RKP02163.1 - 0.1 12.9 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain Clr2_transil PF16761.5 RKP02164.1 - 3.2e-13 50.3 0.0 5.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 OapA_N PF08525.11 RKP02164.1 - 0.084 12.8 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif FAM178 PF14816.6 RKP02164.1 - 0.29 10.1 0.0 0.42 9.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Lactamase_B PF00753.27 RKP02165.1 - 1.3e-18 67.7 5.4 2.8e-18 66.6 5.4 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RKP02165.1 - 3.1e-08 33.4 0.6 3.7e-08 33.1 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3245 PF11595.8 RKP02166.1 - 0.11 13.0 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Cwf_Cwc_15 PF04889.12 RKP02166.1 - 0.32 10.7 4.1 0.52 10.0 4.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RKP02166.1 - 5.6 6.2 6.8 10 5.4 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein GDP_Man_Dehyd PF16363.5 RKP02167.1 - 1.1e-62 212.3 0.0 1.3e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RKP02167.1 - 1.5e-57 194.8 0.1 2.1e-57 194.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 RKP02167.1 - 6.6e-17 61.4 0.0 8.8e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RKP02167.1 - 6.8e-16 58.2 0.0 1.7e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 RKP02167.1 - 4e-12 45.9 0.0 1.5e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RKP02167.1 - 2.8e-10 39.8 0.0 5.3e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 RKP02167.1 - 3.4e-08 33.6 0.1 1.9e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 RKP02167.1 - 1.8e-05 24.3 0.8 0.00035 20.1 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 RKP02167.1 - 0.00036 20.5 1.1 0.001 19.0 1.1 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 RKP02167.1 - 0.0011 18.6 0.5 0.0035 16.9 0.3 1.9 2 1 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 RKP02167.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 RKP02167.1 - 0.1 12.2 0.6 0.47 10.0 0.6 2.1 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase OKR_DC_1_N PF03709.15 RKP02167.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Glyco_transf_28 PF03033.20 RKP02167.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Ldh_1_N PF00056.23 RKP02167.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 RKP02167.1 - 0.21 11.8 0.6 0.49 10.6 0.3 1.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3-HAO PF06052.12 RKP02168.1 - 2e-30 105.4 0.0 2.7e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase RecR PF02132.15 RKP02168.1 - 0.005 16.4 2.4 0.022 14.3 1.2 2.3 2 0 0 2 2 2 1 RecR protein HypA PF01155.19 RKP02168.1 - 0.057 13.4 3.0 0.24 11.4 2.7 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_17 PF17120.5 RKP02168.1 - 0.075 12.7 4.1 0.11 12.1 1.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type OrfB_Zn_ribbon PF07282.11 RKP02168.1 - 0.51 10.3 5.4 2.2 8.3 0.2 2.8 1 1 2 3 3 3 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 RKP02168.1 - 0.59 10.1 8.8 4 7.4 0.2 3.0 2 1 0 2 2 2 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 RKP02168.1 - 1.8 8.6 7.6 2.4 8.2 0.1 2.8 4 0 0 4 4 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 RKP02168.1 - 1.8 8.0 8.1 10 5.7 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 RKP02168.1 - 1.9 8.6 6.9 18 5.4 6.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING-like PF08746.11 RKP02168.1 - 1.9 8.8 8.4 3.9 7.8 5.7 2.6 2 1 0 2 2 2 0 RING-like domain Zn-ribbon_8 PF09723.10 RKP02168.1 - 2.1 8.6 7.3 1.9 8.7 4.0 2.5 2 1 0 2 2 2 0 Zinc ribbon domain Vps36-NZF-N PF16988.5 RKP02168.1 - 4.1 6.9 8.2 79 2.8 8.1 2.4 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain 6PGD PF00393.19 RKP02169.1 - 2.5e-128 427.5 0.0 3.1e-128 427.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 RKP02169.1 - 2.8e-49 167.3 0.0 5.7e-49 166.3 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 RKP02169.1 - 0.0033 18.0 0.1 0.008 16.7 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 RKP02169.1 - 0.087 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CoatB PF10389.9 RKP02169.1 - 0.11 12.4 0.6 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B DNA_pol3_beta PF00712.19 RKP02169.1 - 0.17 12.0 0.1 0.51 10.5 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain Efg1 PF10153.9 RKP02170.1 - 1.9e-11 44.3 4.0 3.1e-11 43.6 4.0 1.4 1 0 0 1 1 1 1 rRNA-processing protein Efg1 TSP_NTD PF17804.1 RKP02170.1 - 0.095 13.0 2.6 0.14 12.4 2.6 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain PHF5 PF03660.14 RKP02171.1 - 3.6e-49 165.3 11.8 4.1e-49 165.1 11.8 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.7 RKP02171.1 - 0.19 11.8 12.8 0.8 9.8 0.7 3.0 1 1 1 2 2 2 0 Double zinc ribbon PolC_DP2 PF03833.13 RKP02171.1 - 4.7 4.9 7.2 5 4.8 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 RKP02171.1 - 9.2 6.7 15.1 0.51 10.7 1.7 2.9 1 1 1 2 2 2 0 C1 domain TFIIA_gamma_N PF02268.16 RKP02172.1 - 1.6e-22 79.2 0.0 2.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 RKP02172.1 - 1.8e-16 60.0 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.14 RKP02172.1 - 0.043 13.6 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase TIM21 PF08294.11 RKP02174.1 - 2.7e-07 30.6 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 TIM21 DEAD PF00270.29 RKP02175.1 - 4.9e-28 98.1 0.0 1.3e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 RKP02175.1 - 3.5e-21 75.5 0.0 5.8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain ResIII PF04851.15 RKP02175.1 - 1.2e-13 51.5 0.0 2.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKP02175.1 - 2.2e-08 34.4 0.0 1.2e-07 32.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 RKP02175.1 - 1.2e-06 28.3 0.6 1e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RKP02175.1 - 3.9e-06 27.3 0.1 0.00045 20.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKP02175.1 - 0.0016 18.7 0.2 0.015 15.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 RKP02175.1 - 0.0045 16.1 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 RKP02175.1 - 0.03 13.9 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SWI2_SNF2 PF18766.1 RKP02175.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HORMA PF02301.18 RKP02176.1 - 5e-46 157.0 0.0 1e-45 156.0 0.0 1.5 2 0 0 2 2 2 1 HORMA domain Ribosomal_S7 PF00177.21 RKP02177.1 - 5.1e-36 123.6 0.4 6.7e-36 123.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DinI PF06183.13 RKP02177.1 - 0.083 13.2 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 DinI-like family ABC_tran PF00005.27 RKP02178.1 - 8.6e-48 162.3 0.0 1e-23 84.4 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKP02178.1 - 7.6e-17 61.5 0.5 4.1e-05 23.1 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RKP02178.1 - 1.6e-15 57.7 2.3 0.0033 17.3 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 RKP02178.1 - 1.1e-08 35.3 0.1 0.012 15.8 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 RKP02178.1 - 3.2e-08 34.3 8.5 0.0083 16.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RKP02178.1 - 8.5e-08 32.6 0.0 0.064 13.5 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.6 RKP02178.1 - 2e-07 31.4 0.0 0.0041 17.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RKP02178.1 - 7.5e-07 28.8 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RKP02178.1 - 7.7e-07 29.7 0.4 0.096 13.1 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 RKP02178.1 - 1.1e-06 28.6 0.1 0.027 14.6 0.0 4.0 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA PF00004.29 RKP02178.1 - 4.2e-06 27.2 0.3 0.087 13.2 0.0 4.7 5 1 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RKP02178.1 - 1.1e-05 25.3 0.0 0.94 9.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 RKP02178.1 - 2.7e-05 24.1 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 RKP02178.1 - 3.2e-05 24.5 0.1 0.14 12.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 RKP02178.1 - 5.3e-05 23.1 0.1 1.5 8.5 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 RKP02178.1 - 0.00014 22.2 0.0 1.4 9.3 0.0 3.5 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 RKP02178.1 - 0.00015 21.7 0.1 0.021 14.8 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 RKP02178.1 - 0.00044 20.0 0.0 1 9.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain Cnd1 PF12717.7 RKP02178.1 - 0.0012 18.9 0.7 0.012 15.6 0.1 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ATPase_2 PF01637.18 RKP02178.1 - 0.0012 18.8 0.0 0.2 11.5 0.0 3.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MeaB PF03308.16 RKP02178.1 - 0.0017 17.4 0.4 0.24 10.3 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Chromo PF00385.24 RKP02178.1 - 0.0017 18.2 0.3 0.005 16.7 0.0 2.0 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT_EZ PF13513.6 RKP02178.1 - 0.0017 18.8 7.3 0.016 15.7 0.3 4.4 3 1 1 4 4 3 1 HEAT-like repeat AAA_7 PF12775.7 RKP02178.1 - 0.0022 17.6 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region HEAT PF02985.22 RKP02178.1 - 0.0026 17.9 2.7 0.014 15.6 0.0 3.7 3 0 0 3 3 1 1 HEAT repeat CLASP_N PF12348.8 RKP02178.1 - 0.0033 17.0 0.1 0.011 15.3 0.1 1.9 2 0 0 2 2 1 1 CLASP N terminal SbcCD_C PF13558.6 RKP02178.1 - 0.004 17.3 0.0 0.2 11.9 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 RKP02178.1 - 0.0055 16.7 0.0 0.86 9.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 RKP02178.1 - 0.0062 16.2 0.2 1.4 8.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RKP02178.1 - 0.0066 15.7 0.0 0.56 9.4 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 RKP02178.1 - 0.0069 16.4 0.0 2.4 8.2 0.0 3.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 RKP02178.1 - 0.0085 16.3 0.0 5.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 RKP02178.1 - 0.0085 15.7 0.1 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMS19_C PF12460.8 RKP02178.1 - 0.012 14.8 1.0 0.037 13.1 0.3 2.1 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal PduV-EutP PF10662.9 RKP02178.1 - 0.014 15.1 0.0 2.4 7.9 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 RKP02178.1 - 0.016 14.9 0.0 4.7 6.9 0.0 3.0 2 1 0 2 2 2 0 Cytidylate kinase DUF1843 PF08898.10 RKP02178.1 - 0.016 15.7 0.9 0.098 13.2 0.9 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) G-alpha PF00503.20 RKP02178.1 - 0.019 14.2 0.1 6 5.9 0.1 2.6 2 0 0 2 2 2 0 G-protein alpha subunit 4HB PF17947.1 RKP02178.1 - 0.022 14.8 0.1 0.076 13.1 0.1 2.0 1 0 0 1 1 1 0 Four helical bundle domain DUF87 PF01935.17 RKP02178.1 - 0.026 14.6 0.2 11 6.0 0.0 3.4 3 0 0 3 3 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 RKP02178.1 - 0.027 14.3 0.0 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 RKP02178.1 - 0.033 14.5 0.1 53 4.1 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 RKP02178.1 - 0.038 14.0 0.0 5.5 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FAA_hydro_N_2 PF18288.1 RKP02178.1 - 0.06 13.8 0.5 2.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 AAA_17 PF13207.6 RKP02178.1 - 0.07 13.6 11.6 3 8.3 0.0 4.7 5 1 0 5 5 3 0 AAA domain NTPase_1 PF03266.15 RKP02178.1 - 0.071 13.0 0.1 19 5.1 0.0 3.5 3 0 0 3 3 3 0 NTPase HEAT_2 PF13646.6 RKP02178.1 - 0.1 13.0 4.2 1.7 9.1 0.1 3.6 2 2 2 4 4 3 0 HEAT repeats HBS1_N PF08938.10 RKP02178.1 - 0.17 12.2 3.5 13 6.1 0.1 3.6 3 0 0 3 3 2 0 HBS1 N-terminus TetR_C_31 PF17940.1 RKP02178.1 - 1 9.6 4.9 0.23 11.7 0.2 2.4 3 0 0 3 3 1 0 Tetracyclin repressor-like, C-terminal domain AAA_13 PF13166.6 RKP02178.1 - 1.2 7.7 0.0 1.2 7.7 0.0 3.7 5 0 0 5 5 4 0 AAA domain LIN37 PF15306.6 RKP02179.1 - 0.054 13.7 0.1 20 5.4 0.0 2.7 3 0 0 3 3 3 0 LIN37 Rhomboid PF01694.22 RKP02180.1 - 1.8e-31 109.2 14.8 1.8e-31 109.2 14.8 2.5 2 1 1 3 3 3 1 Rhomboid family DUF2070 PF09843.9 RKP02180.1 - 0.17 10.2 2.3 0.28 9.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VKOR PF07884.14 RKP02180.1 - 4 7.6 10.7 0.82 9.9 5.3 2.7 2 1 0 2 2 2 0 Vitamin K epoxide reductase family Rad60-SLD PF11976.8 RKP02181.1 - 7e-22 77.0 0.2 8.5e-22 76.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RKP02181.1 - 9e-11 41.4 0.2 1.1e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family SH3_1 PF00018.28 RKP02181.1 - 0.044 13.4 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 SH3 domain CdhC PF03598.15 RKP02181.1 - 0.055 13.3 0.2 0.34 10.8 0.1 1.9 1 1 1 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit DUF3336 PF11815.8 RKP02183.1 - 2.5e-36 124.4 0.2 3.9e-36 123.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RKP02183.1 - 1.3e-16 61.4 0.0 3.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TAF1_subA PF14929.6 RKP02183.1 - 0.05 13.0 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A Tctex-1 PF03645.13 RKP02184.1 - 6.4e-31 106.6 0.5 7.4e-31 106.5 0.5 1.0 1 0 0 1 1 1 1 Tctex-1 family Glycogen_syn PF05693.13 RKP02185.1 - 0 1066.7 0.0 0 1066.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 RKP02185.1 - 5.1e-07 29.4 0.0 0.00026 20.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 RKP02185.1 - 1.2e-06 28.4 0.1 7.5e-06 25.8 0.1 2.2 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 RKP02185.1 - 5.9e-06 26.7 0.0 0.0057 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RKP02185.1 - 2e-05 25.1 0.1 5.3e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 RKP02185.1 - 0.0003 20.9 0.1 0.00082 19.4 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pkinase PF00069.25 RKP02186.1 - 3.1e-57 194.0 0.0 2.3e-56 191.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02186.1 - 5.3e-27 94.7 0.1 7.9e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RKP02186.1 - 4.4e-05 23.5 0.8 0.0013 18.7 0.0 2.8 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP02186.1 - 0.00072 19.0 0.0 0.0038 16.6 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 RKP02186.1 - 0.008 15.5 0.0 0.023 14.1 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP02186.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 RKP02186.1 - 0.022 13.9 0.0 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_C PF00433.24 RKP02186.1 - 0.088 13.5 0.2 0.4 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein kinase C terminal domain S1-P1_nuclease PF02265.16 RKP02187.1 - 7.4e-55 186.5 0.4 8.4e-55 186.3 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Pkinase PF00069.25 RKP02188.1 - 5.4e-61 206.3 0.0 6.3e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02188.1 - 1.2e-45 155.9 0.0 1.4e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP02188.1 - 7.3e-05 21.7 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKP02188.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like mRNA_cap_enzyme PF01331.19 RKP02189.1 - 4.6e-06 26.6 0.0 6.2e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain PPR_2 PF13041.6 RKP02190.1 - 2.4e-10 40.5 1.6 3.9e-06 26.9 0.1 3.5 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 RKP02190.1 - 0.00041 20.4 0.0 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_19 PF14559.6 RKP02190.1 - 0.0049 17.4 0.0 3 8.4 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_1 PF12854.7 RKP02190.1 - 0.15 11.7 0.0 9.5 6.0 0.0 3.5 4 0 0 4 4 4 0 PPR repeat Pkinase PF00069.25 RKP02191.1 - 2.1e-70 237.1 0.0 2.6e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02191.1 - 5.5e-31 107.8 0.0 7.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RKP02191.1 - 1.3e-09 38.6 2.0 2.3e-09 37.8 2.0 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RKP02191.1 - 6.5e-07 28.9 0.0 4.9e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKP02191.1 - 9.5e-05 21.5 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP02191.1 - 0.00032 20.1 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RKP02191.1 - 0.001 18.7 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKP02191.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKP02191.1 - 0.083 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pep_deformylase PF01327.21 RKP02192.1 - 2.4e-32 111.8 0.0 2.8e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase DUF3668 PF12416.8 RKP02193.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 Cep120 protein C2 PF00168.30 RKP02193.1 - 0.046 14.0 0.0 0.24 11.7 0.0 2.2 3 0 0 3 3 3 0 C2 domain Ribosomal_S4e PF00900.20 RKP02194.1 - 2.5e-33 113.8 0.0 5.2e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 RKP02194.1 - 1.1e-22 79.4 0.0 1.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 RKP02194.1 - 4.3e-15 55.5 6.0 8.1e-15 54.6 6.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 RKP02194.1 - 3.7e-06 26.6 0.0 7.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 RKP02194.1 - 3.1e-05 23.8 1.3 3.1e-05 23.8 1.3 2.2 2 0 0 2 2 2 1 KOW motif HAD PF12710.7 RKP02195.1 - 8.7e-19 68.7 0.0 2.3e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKP02195.1 - 8e-16 59.0 0.3 1.9e-15 57.7 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 RKP02195.1 - 2e-09 37.3 2.5 6.5e-09 35.7 0.3 2.5 2 0 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.12 RKP02195.1 - 2.5e-08 34.0 0.0 2.8e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RKP02195.1 - 0.0036 17.4 0.1 3.9 7.5 0.0 3.1 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 RKP02195.1 - 0.0069 15.8 0.0 0.5 9.7 0.0 2.4 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.12 RKP02195.1 - 0.015 14.8 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) SPX PF03105.19 RKP02195.1 - 0.06 13.3 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 SPX domain MMM1 PF10296.9 RKP02196.1 - 0.0043 16.1 0.0 0.13 11.2 0.0 2.6 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 Cofilin_ADF PF00241.20 RKP02198.1 - 2.1e-20 72.7 0.0 2.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 RKP02201.1 - 5.6e-05 22.7 0.0 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RKP02201.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP02201.1 - 0.00023 20.8 0.0 0.0017 18.0 0.0 2.4 2 1 1 3 3 3 1 Variant SH3 domain YccF PF03733.13 RKP02202.1 - 1.2e-22 80.3 21.3 3.6e-11 43.6 9.8 2.1 2 0 0 2 2 2 2 Inner membrane component domain Pkinase PF00069.25 RKP02203.1 - 1.3e-51 175.5 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02203.1 - 1.5e-28 99.8 0.0 2.8e-28 98.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02203.1 - 1.3e-05 24.6 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP02203.1 - 0.0003 20.8 0.5 0.00066 19.7 0.5 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 RKP02203.1 - 0.0044 16.4 0.0 0.009 15.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RKP02203.1 - 0.006 16.2 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 RKP02203.1 - 0.01 14.8 0.0 0.024 13.6 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 RKP02203.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 RKP02203.1 - 0.027 14.1 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Molybdopterin PF00384.22 RKP02204.1 - 4.4e-56 190.7 0.0 1.3e-54 185.9 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 RKP02204.1 - 1.1e-18 67.0 0.4 3.4e-18 65.4 0.4 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 RKP02204.1 - 2e-16 59.2 1.9 2.1e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 RKP02204.1 - 2.8e-13 50.3 1.5 7.3e-13 49.0 1.5 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 RKP02204.1 - 7.5e-08 32.2 0.6 2.1e-07 30.8 0.6 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 RKP02204.1 - 0.023 14.4 0.2 0.42 10.4 0.2 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 RKP02204.1 - 0.14 12.0 1.1 4.5 7.2 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_S19 PF00203.21 RKP02205.1 - 1.8e-23 82.2 0.0 2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 P34-Arc PF04045.14 RKP02206.1 - 1.7e-102 342.2 0.0 2e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc FAD_binding_1 PF00667.20 RKP02207.1 - 5.6e-38 130.7 0.0 8.8e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RKP02207.1 - 2.1e-20 73.4 1.1 4.5e-20 72.3 0.3 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 RKP02207.1 - 1.2e-17 64.6 0.0 2.7e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ndufs5 PF10200.9 RKP02210.1 - 3.5e-06 27.2 0.3 3.8e-06 27.1 0.3 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 RKP02210.1 - 0.00021 21.4 5.2 0.00028 20.9 5.2 1.2 1 0 0 1 1 1 1 CHCH domain VPS11_C PF12451.8 RKP02210.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal COX17 PF05051.13 RKP02210.1 - 0.028 14.7 1.4 0.046 14.1 1.4 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 RKP02210.1 - 0.53 10.7 5.5 4.6 7.7 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Ribosomal_S9 PF00380.19 RKP02211.1 - 6.4e-34 117.1 0.2 7.3e-34 116.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 RKP02212.1 - 1.1e-69 233.9 2.5 1.4e-69 233.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e PPTA PF01239.22 RKP02215.1 - 1.5e-40 135.8 10.3 1e-09 37.8 1.7 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 RKP02215.1 - 3.2 8.3 5.7 9.6 6.8 0.1 3.9 4 2 1 5 5 5 0 Tetratricopeptide repeat Dala_Dala_lig_C PF07478.13 RKP02216.1 - 1.6e-14 54.0 0.0 2.1e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 RKP02216.1 - 0.0081 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 RKP02216.1 - 0.01 15.3 0.3 0.026 14.0 0.2 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ESSS PF10183.9 RKP02217.1 - 1.7e-06 28.2 0.0 1.8e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-C2H2 PF00096.26 RKP02218.1 - 1.1e-10 41.4 7.1 4.7e-06 26.8 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02218.1 - 1.2e-07 31.9 5.6 0.0047 17.7 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP02218.1 - 0.0003 21.1 0.5 0.0003 21.1 0.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 RKP02218.1 - 0.0017 18.3 7.2 0.015 15.2 0.3 3.0 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 RKP02218.1 - 0.002 18.4 0.4 0.0073 16.6 0.4 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 RKP02218.1 - 0.0042 17.7 0.9 0.047 14.3 0.7 2.0 1 1 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 RKP02218.1 - 0.018 14.8 0.7 0.035 13.9 0.7 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-LYAR PF08790.11 RKP02218.1 - 0.089 12.7 1.2 5 7.1 0.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met PF12874.7 RKP02218.1 - 0.67 10.4 4.5 4.1 7.9 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MRG PF05712.13 RKP02219.1 - 1.2e-51 174.8 0.4 1.9e-51 174.2 0.4 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 RKP02219.1 - 7.7e-10 38.5 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 RKP02219.1 - 0.063 13.2 0.4 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FCH PF00611.23 RKP02220.1 - 1e-12 48.1 4.1 4.4e-12 46.1 0.8 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain muHD PF10291.9 RKP02220.1 - 1.4e-12 47.6 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Ank_4 PF13637.6 RKP02221.1 - 1.2e-17 64.1 0.0 2e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKP02221.1 - 3.3e-17 62.8 0.1 2.6e-16 60.0 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKP02221.1 - 3.4e-16 57.7 0.1 5e-05 23.4 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RKP02221.1 - 2.2e-15 56.5 2.5 1.4e-05 25.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 RKP02221.1 - 1.3e-14 53.8 1.9 8.1e-06 26.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat FYVE PF01363.21 RKP02222.1 - 1e-17 64.0 4.1 1.1e-17 63.9 4.1 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 RKP02222.1 - 0.00016 21.8 2.8 0.00018 21.7 2.8 1.0 1 0 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 RKP02222.1 - 0.013 15.4 7.4 0.018 14.9 7.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.21 RKP02222.1 - 0.088 13.0 8.3 0.18 12.0 8.3 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-CRD PF17979.1 RKP02222.1 - 0.15 12.2 5.7 0.15 12.1 5.7 1.0 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions DZR PF12773.7 RKP02222.1 - 0.26 11.3 6.9 2.1 8.5 6.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-AN1 PF01428.16 RKP02222.1 - 0.32 11.2 9.1 1.1 9.4 4.2 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger Nudix_N_2 PF14803.6 RKP02222.1 - 2.8 7.9 11.2 5.3 7.0 4.7 3.0 1 1 1 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 RKP02222.1 - 5.2 6.6 9.8 19 4.9 4.0 2.9 2 1 1 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.12 RKP02223.1 - 3.5e-19 69.1 20.8 3.5e-19 69.1 20.8 4.0 2 1 1 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 RKP02223.1 - 7.7e-18 64.3 0.9 7.7e-18 64.3 0.9 5.2 2 1 5 7 7 7 1 Zinc-ribbon zf-RING_2 PF13639.6 RKP02223.1 - 3.9e-08 33.5 12.7 3.9e-08 33.5 12.7 5.4 2 1 3 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKP02223.1 - 7.5e-05 22.5 12.3 7.5e-05 22.5 12.3 6.4 4 2 2 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKP02223.1 - 0.0014 18.3 6.4 0.0014 18.3 6.4 5.0 5 0 0 5 5 5 1 RING-like zinc finger zf-RING_UBOX PF13445.6 RKP02223.1 - 0.0065 16.5 8.3 0.0065 16.5 8.3 5.0 5 3 0 5 5 5 1 RING-type zinc-finger zf-RING_5 PF14634.6 RKP02223.1 - 0.0074 16.2 13.8 0.0074 16.2 13.8 6.5 4 2 1 5 5 5 1 zinc-RING finger domain CTP_transf_like PF01467.26 RKP02224.1 - 3.1e-24 85.8 0.0 4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like CIAPIN1 PF05093.13 RKP02225.1 - 4.6e-20 72.0 13.5 3.7e-19 69.1 2.5 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PNRC PF15365.6 RKP02226.1 - 7.1e-08 32.0 0.7 7.1e-08 32.0 0.7 7.4 8 0 0 8 8 8 2 Proline-rich nuclear receptor coactivator motif Pterin_bind PF00809.22 RKP02227.1 - 1.8e-54 185.0 0.0 2.4e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 RKP02227.1 - 3.2e-32 111.4 0.0 5.8e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NOA36 PF06524.12 RKP02228.1 - 0.98 8.7 5.2 2 7.7 5.2 1.4 1 0 0 1 1 1 0 NOA36 protein ANAPC4_WD40 PF12894.7 RKP02229.1 - 1.4e-14 54.1 3.4 0.011 16.0 0.0 6.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 RKP02229.1 - 2.5e-05 23.5 3.3 0.65 9.0 0.0 4.6 5 0 0 5 5 5 2 Coatomer WD associated region Clathrin PF00637.20 RKP02229.1 - 3.2e-05 23.8 1.1 5.5 6.9 0.0 6.4 7 0 0 7 7 7 1 Region in Clathrin and VPS WD40 PF00400.32 RKP02229.1 - 0.00088 20.0 1.1 0.3 12.0 0.0 4.6 4 0 0 4 4 3 1 WD domain, G-beta repeat ANAPC3 PF12895.7 RKP02229.1 - 0.0066 16.7 9.4 34 4.8 0.2 7.7 8 0 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 RKP02229.1 - 0.014 15.6 13.2 14 6.2 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 RKP02229.1 - 0.026 13.5 1.5 0.5 9.3 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DZR PF12773.7 RKP02229.1 - 0.05 13.6 6.0 0.22 11.6 6.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon PD40 PF07676.12 RKP02229.1 - 0.071 13.1 0.0 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TPR_1 PF00515.28 RKP02229.1 - 0.99 9.3 19.5 5.3 7.0 0.3 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKP02229.1 - 1.2 9.4 26.0 15 5.9 0.2 10.4 10 1 0 10 10 10 0 Tetratricopeptide repeat zf-C5HC2 PF02928.16 RKP02229.1 - 3.8 8.0 5.6 12 6.4 5.6 1.9 1 0 0 1 1 1 0 C5HC2 zinc finger Dynamin_N PF00350.23 RKP02230.1 - 1.1e-17 64.6 0.0 4.6e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 RKP02230.1 - 1.3e-10 41.4 0.0 2.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKP02230.1 - 5.4e-07 29.4 0.0 0.00023 20.8 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 RKP02230.1 - 0.0078 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 RKP02230.1 - 0.0087 15.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 RKP02230.1 - 0.0099 15.8 0.1 2.2 8.2 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase TsaE PF02367.17 RKP02230.1 - 0.016 15.2 0.0 0.041 13.9 0.0 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 RKP02230.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein IIGP PF05049.13 RKP02230.1 - 0.049 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 RKP02230.1 - 8 6.8 12.1 0.78 10.1 0.0 3.4 2 1 1 3 3 3 0 AAA ATPase domain Ribosomal_L22 PF00237.19 RKP02231.1 - 3.9e-37 126.6 0.7 3.9e-37 126.6 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e zf-C3HC4 PF00097.25 RKP02232.1 - 3.2e-08 33.3 0.5 3.2e-08 33.3 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP02232.1 - 1.2e-07 31.5 2.5 1.2e-07 31.5 2.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP02232.1 - 9.8e-07 28.6 0.8 2.1e-06 27.6 0.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKP02232.1 - 1.4e-06 28.2 1.5 1.4e-06 28.2 1.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RKP02232.1 - 7.1e-06 25.8 5.1 3e-05 23.8 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKP02232.1 - 2e-05 24.6 1.4 2e-05 24.6 1.4 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 RKP02232.1 - 4.7e-05 23.6 3.3 4.7e-05 23.6 3.3 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 RKP02232.1 - 0.0077 16.1 5.9 0.014 15.2 2.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RKP02232.1 - 0.062 13.6 1.3 0.062 13.6 1.3 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain IBR PF01485.21 RKP02232.1 - 0.19 11.9 1.5 0.38 11.0 0.4 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SelP_N PF04592.14 RKP02232.1 - 6.7 6.0 6.1 11 5.4 6.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glutaredoxin PF00462.24 RKP02234.1 - 1.4e-38 130.9 0.0 1.1e-18 67.2 0.0 3.4 4 0 0 4 4 4 2 Glutaredoxin SH3BGR PF04908.15 RKP02234.1 - 8.3e-07 29.1 0.0 0.00054 20.1 0.0 3.3 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein HyaE PF07449.11 RKP02234.1 - 2.1e-05 24.4 0.3 0.014 15.3 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 RKP02234.1 - 0.017 15.1 0.0 0.071 13.1 0.0 2.1 1 1 0 2 2 2 0 Thioredoxin RdRP PF05183.12 RKP02234.1 - 0.018 13.7 0.0 4.2 5.9 0.0 2.1 1 1 0 2 2 2 0 RNA dependent RNA polymerase CNOT1_HEAT_N PF16419.5 RKP02234.1 - 0.029 14.0 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat LEM PF03020.15 RKP02234.1 - 0.077 12.6 0.0 0.71 9.5 0.0 2.5 2 0 0 2 2 2 0 LEM domain DNA_processg_A PF02481.15 RKP02234.1 - 0.14 11.4 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 DNA recombination-mediator protein A Thioredoxin_2 PF13098.6 RKP02234.1 - 0.18 12.3 0.1 4.9 7.6 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin-like domain RRM_1 PF00076.22 RKP02235.1 - 1.8e-38 130.2 0.0 1.6e-18 66.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP02235.1 - 0.00016 21.7 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 RKP02235.1 - 0.0017 18.0 0.0 0.025 14.2 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 RKP02235.1 - 0.0082 15.8 0.2 3.6 7.3 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_occluded PF16842.5 RKP02235.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 RKP02235.1 - 0.12 12.6 0.0 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Tcp11 PF05794.13 RKP02236.1 - 4.6e-70 236.9 5.9 5.7e-70 236.6 5.9 1.1 1 0 0 1 1 1 1 T-complex protein 11 SOG2 PF10428.9 RKP02236.1 - 0.76 8.9 6.1 1.3 8.1 6.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein AFG1_ATPase PF03969.16 RKP02237.1 - 3.2e-94 315.8 0.0 3.2e-90 302.7 0.0 2.7 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 RKP02237.1 - 0.00032 21.1 2.9 0.013 15.8 0.0 3.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 RKP02237.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RKP02237.1 - 0.018 14.7 0.0 0.083 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RKP02237.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Methyltransf_15 PF09445.10 RKP02238.1 - 2.9e-28 98.5 0.0 6.1e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 RKP02238.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 RKP02238.1 - 0.0039 17.9 0.3 0.0087 16.7 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RKP02238.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 DNA_methylase PF00145.17 RKP02238.1 - 0.24 10.7 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 RKP02239.1 - 4e-28 98.1 0.0 6.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 RKP02239.1 - 0.00017 21.4 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RKP02239.1 - 0.0011 18.6 0.0 0.0037 16.9 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 RKP02239.1 - 0.12 13.0 0.0 0.19 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 RKP02240.1 - 6.7e-42 140.7 18.1 2.1e-07 31.5 0.2 12.7 13 0 0 13 13 13 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02240.1 - 5e-21 74.8 0.0 0.0016 18.7 0.0 8.9 4 2 7 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 RKP02240.1 - 4.1e-10 39.9 0.1 6.3e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 RKP02240.1 - 8.9e-07 28.2 0.6 1.9 7.3 0.0 5.0 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKP02240.1 - 3.6e-06 27.0 1.1 0.14 12.0 0.1 4.3 3 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 RKP02240.1 - 0.0018 17.4 0.4 0.21 10.6 0.0 3.1 3 1 0 4 4 4 1 Protein of unknown function (DUF1513) WD40_like PF17005.5 RKP02240.1 - 0.0019 17.6 0.0 0.16 11.3 0.0 3.2 3 1 1 4 4 4 1 WD40-like domain ELYS-bb PF16687.5 RKP02240.1 - 0.0053 15.4 0.0 0.08 11.5 0.0 2.4 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 RKP02240.1 - 0.039 12.6 1.3 3.4 6.2 0.1 3.8 3 2 2 5 5 5 0 Nucleoporin Nup120/160 Sec23_trunk PF04811.15 RKP02241.1 - 2.8e-74 249.8 0.0 4e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 RKP02241.1 - 9.9e-30 103.1 0.1 1.9e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 RKP02241.1 - 4.3e-24 84.3 0.3 8.5e-24 83.3 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 RKP02241.1 - 9.8e-16 57.5 8.1 1.9e-15 56.6 8.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RKP02241.1 - 2.8e-13 49.6 0.0 6.1e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 RKP02241.1 - 0.046 13.1 0.2 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain LRR_8 PF13855.6 RKP02242.1 - 7.6e-44 147.3 37.5 6.2e-11 41.9 0.9 9.3 3 3 8 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 RKP02242.1 - 1.2e-41 140.0 29.8 4.6e-05 23.7 0.1 10.1 7 2 3 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP02242.1 - 1.5e-13 49.2 28.1 0.077 13.6 0.0 12.4 11 3 2 13 13 13 4 Leucine Rich Repeat LRR_9 PF14580.6 RKP02242.1 - 1.4e-08 34.4 19.5 0.00096 18.7 0.3 5.5 3 2 2 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 RKP02242.1 - 0.13 12.3 32.1 29 5.1 0.1 11.0 12 0 0 12 12 12 0 Leucine Rich repeat CSTF_C PF14304.6 RKP02242.1 - 2.1 8.0 4.5 19 4.9 0.4 3.7 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal ASH PF15780.5 RKP02243.1 - 4.3e-05 23.7 0.3 0.0026 17.9 0.0 2.5 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 RKP02243.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 131-like Ribosomal_S10 PF00338.22 RKP02244.1 - 6.6e-25 87.2 0.1 8.3e-25 86.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Serglycin PF04360.12 RKP02245.1 - 0.27 11.2 0.5 0.35 10.8 0.5 1.2 1 0 0 1 1 1 0 Serglycin Spt20 PF12090.8 RKP02246.1 - 0.0011 18.6 25.7 0.0086 15.7 7.8 2.4 2 0 0 2 2 2 2 Spt20 family Yippee-Mis18 PF03226.14 RKP02246.1 - 0.0071 16.5 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 RKP02246.1 - 1.6 8.8 5.0 3.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon Homoserine_dh PF00742.19 RKP02247.1 - 7.4e-52 175.7 0.1 1e-51 175.3 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 RKP02247.1 - 9.3e-12 45.6 0.0 2.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Ydr279_N PF17745.1 RKP02250.1 - 4.8e-11 42.7 0.0 8.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 RKP02250.1 - 0.0051 17.0 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain V-SNARE_C PF12352.8 RKP02251.1 - 6.7e-14 51.9 1.6 1.2e-13 51.1 1.0 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RKP02251.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Sec20 DUF3450 PF11932.8 RKP02251.1 - 0.017 14.5 3.6 0.031 13.6 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4337 PF14235.6 RKP02251.1 - 0.042 14.0 1.9 1.4 9.1 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HALZ PF02183.18 RKP02251.1 - 0.075 13.3 1.4 0.14 12.4 0.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper SKA2 PF16740.5 RKP02251.1 - 0.12 12.2 4.2 0.3 10.9 2.2 2.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 YkyA PF10368.9 RKP02251.1 - 0.14 11.9 2.6 0.11 12.2 0.5 1.8 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein DUF4407 PF14362.6 RKP02251.1 - 0.15 11.4 8.1 0.62 9.4 8.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MDMPI_N PF11716.8 RKP02251.1 - 2.2 9.0 10.1 2.2 8.9 4.6 2.2 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain AIM24 PF01987.17 RKP02253.1 - 5.3e-10 39.4 0.1 4.6e-09 36.4 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 SOG2 PF10428.9 RKP02253.1 - 2.2 7.4 15.2 4.2 6.4 15.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2909 PF11137.8 RKP02254.1 - 0.11 12.4 0.9 8.1 6.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) ABC_membrane_2 PF06472.15 RKP02255.1 - 1.8e-93 312.9 2.9 2.8e-93 312.2 2.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RKP02255.1 - 2.1e-14 54.2 0.0 6.8e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RKP02255.1 - 8.4e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKP02255.1 - 0.0084 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RKP02255.1 - 0.025 15.1 0.2 0.086 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RKP02255.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 RKP02255.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF498 PF04430.14 RKP02256.1 - 1.7e-28 98.8 0.0 1.9e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) AAA PF00004.29 RKP02256.1 - 0.18 12.2 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dUTPase PF00692.19 RKP02257.1 - 1.5e-38 131.4 0.0 1.7e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase CoaE PF01121.20 RKP02258.1 - 9.5e-51 172.0 0.1 1.3e-50 171.6 0.1 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 RKP02258.1 - 0.0002 21.9 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKP02258.1 - 0.0023 18.1 0.1 0.017 15.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain HTH_ABP1_N PF18107.1 RKP02258.1 - 0.005 16.5 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain TetR_C_32 PF09209.11 RKP02258.1 - 0.0097 15.9 0.7 0.018 15.1 0.7 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain SKI PF01202.22 RKP02258.1 - 0.058 13.5 0.3 5.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase LacI PF00356.21 RKP02258.1 - 0.086 12.7 0.3 9.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family dNK PF01712.19 RKP02258.1 - 0.11 12.3 0.1 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 RKP02258.1 - 0.16 12.2 1.1 2.1 8.6 1.1 2.5 1 1 0 1 1 1 0 AAA domain XendoU PF09412.10 RKP02259.1 - 1.9e-72 243.7 0.0 2.8e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU AWPM-19 PF05512.11 RKP02259.1 - 0.54 10.4 1.6 0.99 9.6 1.6 1.3 1 0 0 1 1 1 0 AWPM-19-like family Hydrolase_4 PF12146.8 RKP02260.1 - 1.5e-27 96.4 0.0 1.2e-24 86.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKP02260.1 - 4.4e-12 46.2 0.1 5.9e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 RKP02260.1 - 4.7e-08 33.0 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 RKP02260.1 - 1.4e-06 29.1 1.2 2.3e-06 28.4 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RKP02260.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 RKP02260.1 - 0.032 13.7 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 RKP02260.1 - 0.037 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 RKP02260.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 RKP02260.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family TFIIS_M PF07500.14 RKP02262.1 - 1.6e-11 44.7 0.0 3.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 RKP02262.1 - 2.8e-11 43.5 0.0 5.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 RKP02262.1 - 9.4e-10 38.2 8.4 1.5e-09 37.6 8.4 1.3 1 0 0 1 1 1 1 PHD-finger Terminase_GpA PF05876.12 RKP02262.1 - 0.0022 16.6 0.2 0.0031 16.1 0.2 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) CAP PF00188.26 RKP02263.1 - 4.5e-11 43.7 3.9 5.5e-11 43.4 3.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Acetyltransf_3 PF13302.7 RKP02264.1 - 3.3e-23 82.9 0.0 4.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKP02264.1 - 2.6e-06 27.7 0.0 4.2e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 RKP02264.1 - 9.4e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RKP02264.1 - 5.7e-05 22.8 0.6 0.034 13.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKP02264.1 - 0.00062 19.7 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RKP02264.1 - 0.009 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKP02264.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_pol_Rpb2_6 PF00562.28 RKP02267.1 - 3.4e-122 408.3 0.2 4.9e-122 407.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RKP02267.1 - 1.7e-66 223.6 0.0 2.5e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 RKP02267.1 - 6.5e-49 166.2 0.2 6.7e-48 162.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 RKP02267.1 - 1.5e-34 118.2 0.2 3.4e-34 117.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 RKP02267.1 - 6.4e-25 87.1 0.0 1.4e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RKP02267.1 - 1.3e-24 86.2 0.1 2.9e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 RKP02267.1 - 8.9e-18 64.6 0.1 3e-17 62.9 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 RKP02267.1 - 0.16 12.7 0.4 0.39 11.5 0.4 1.6 1 0 0 1 1 1 0 MRN-interacting protein Ribosomal_S6e PF01092.19 RKP02268.1 - 4.6e-55 184.9 0.4 1.4e-54 183.4 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein S6e Tau95 PF09734.9 RKP02269.1 - 1.2e-23 84.5 0.0 3.1e-23 83.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 RKP02269.1 - 2.8e-14 53.4 0.0 1.3e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 Tau95 Triple barrel domain Calcipressin PF04847.12 RKP02270.1 - 1.4e-12 47.8 0.0 1.2e-11 44.7 0.0 2.2 2 1 0 2 2 2 1 Calcipressin DUF3619 PF12279.8 RKP02270.1 - 0.41 11.0 6.5 7.6 6.9 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) KAP PF05804.12 RKP02272.1 - 5.7e-102 342.1 0.6 1.5e-101 340.8 0.6 1.7 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) RabGAP-TBC PF00566.18 RKP02273.1 - 2.2e-08 34.0 0.3 0.0062 16.2 0.0 3.1 3 0 0 3 3 3 3 Rab-GTPase-TBC domain TFIIA PF03153.13 RKP02274.1 - 0.63 10.0 42.5 1.2 9.1 42.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 RKP02274.1 - 4.4 5.5 15.6 9 4.5 15.6 1.4 1 0 0 1 1 1 0 CDC45-like protein ADH_N PF08240.12 RKP02276.1 - 5.2e-27 93.9 0.2 1.1e-26 92.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKP02276.1 - 4.8e-14 52.4 0.1 4.9e-11 42.7 0.0 2.4 1 1 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RKP02276.1 - 0.00049 19.6 0.2 0.002 17.6 0.0 2.0 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus zf-C2H2 PF00096.26 RKP02277.1 - 7.1e-14 51.4 1.1 3.8e-07 30.2 0.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKP02277.1 - 6.1e-09 35.9 10.2 2.1e-05 24.7 0.2 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKP02277.1 - 8.4e-08 32.4 5.5 2.5e-05 24.7 0.8 2.4 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RKP02277.1 - 0.00089 19.2 0.2 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKP02277.1 - 0.0016 18.1 4.7 0.15 11.8 0.8 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RKP02277.1 - 0.004 16.9 4.7 0.051 13.3 0.8 2.4 2 1 0 2 2 2 1 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 RKP02277.1 - 0.0052 16.7 5.5 0.14 12.1 1.0 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zf-met PF12874.7 RKP02277.1 - 0.014 15.8 0.2 0.028 14.8 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RKP02277.1 - 0.024 14.2 0.2 0.051 13.2 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 RKP02277.1 - 0.029 14.7 1.8 0.035 14.4 1.1 1.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RKP02277.1 - 0.032 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RKP02277.1 - 0.058 13.3 6.7 1.9 8.5 0.8 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type TMEM154 PF15102.6 RKP02278.1 - 0.029 14.3 0.4 0.069 13.1 0.4 1.6 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 RKP02278.1 - 0.058 13.6 0.2 0.058 13.6 0.2 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator TPR_2 PF07719.17 RKP02279.1 - 6.3e-05 22.8 6.5 0.22 11.7 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02279.1 - 0.00044 20.0 1.6 2.3 8.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKP02279.1 - 0.0018 18.6 1.3 2.3 8.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP02279.1 - 0.005 16.8 0.9 0.46 10.6 0.0 3.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RKP02279.1 - 0.036 14.7 0.1 0.52 11.0 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKP02279.1 - 0.15 12.7 3.0 67 4.4 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat HSP20 PF00011.21 RKP02280.1 - 1.5e-10 41.1 0.2 1.7e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family CitX PF03802.14 RKP02280.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase CS PF04969.16 RKP02280.1 - 0.033 15.2 0.0 0.073 14.1 0.0 1.6 1 0 0 1 1 1 0 CS domain Asp PF00026.23 RKP02282.1 - 1.9e-109 365.9 0.5 2.2e-109 365.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKP02282.1 - 8.6e-13 48.9 1.0 1.8e-09 38.1 0.6 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RKP02282.1 - 6.1e-06 26.1 0.0 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RKP02282.1 - 0.0029 18.2 0.3 0.99 10.1 0.1 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RKP02282.1 - 0.012 16.2 0.0 4.6 7.9 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Cyclin PF08613.11 RKP02283.1 - 2.2e-30 106.2 0.0 3.1e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 RKP02283.1 - 0.0041 16.8 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Phage_GPD PF05954.11 RKP02284.1 - 0.069 12.4 0.7 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Med11 PF10280.9 RKP02285.1 - 0.0002 21.9 2.6 0.00028 21.3 2.6 1.3 1 0 0 1 1 1 1 Mediator complex protein ALIX_LYPXL_bnd PF13949.6 RKP02285.1 - 0.019 14.3 3.8 0.026 13.8 1.0 1.9 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV HAUS6_N PF14661.6 RKP02287.1 - 5.4e-21 75.2 0.3 9.9e-21 74.4 0.3 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus DUF4764 PF15961.5 RKP02288.1 - 1.7 7.2 17.6 2.4 6.7 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) FYVE PF01363.21 RKP02289.1 - 2.4e-13 50.0 8.9 2.4e-13 50.0 8.9 2.6 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 RKP02289.1 - 6.2e-05 22.7 2.5 0.00015 21.4 2.5 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain RabGAP-TBC PF00566.18 RKP02290.1 - 7.9e-55 185.8 0.7 1.3e-54 185.2 0.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain LPD5 PF18799.1 RKP02290.1 - 0.089 13.2 1.4 0.27 11.6 1.0 2.0 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 5 GAS PF13851.6 RKP02290.1 - 0.13 11.6 17.7 0.89 8.9 6.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 RKP02290.1 - 0.72 10.1 6.4 4.8 7.5 0.3 4.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper T7SS_ESX_EspC PF10824.8 RKP02290.1 - 0.9 10.0 7.5 4.5 7.8 2.5 3.0 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm PI3K_P85_iSH2 PF16454.5 RKP02290.1 - 2.5 7.7 10.6 4.6 6.8 10.6 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ABC_tran_CTD PF16326.5 RKP02290.1 - 4 7.8 17.4 1.1 9.6 9.0 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 RKP02290.1 - 5.9 5.7 15.9 4 6.2 3.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 RKP02290.1 - 7 6.7 11.9 13 5.9 10.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mei5 PF10376.9 RKP02290.1 - 7.5 6.4 13.9 26 4.6 11.2 2.1 1 1 1 2 2 2 0 Double-strand recombination repair protein CENP-F_leu_zip PF10473.9 RKP02290.1 - 9.4 6.3 17.1 1.7 8.6 6.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CH PF00307.31 RKP02291.1 - 3.4e-80 265.3 1.0 4.6e-21 75.0 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RKP02291.1 - 4.9e-07 29.5 0.2 0.0045 16.8 0.0 3.4 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_7 PF13499.6 RKP02291.1 - 8.6e-05 22.9 0.0 0.0003 21.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair CH_2 PF06294.11 RKP02291.1 - 0.037 14.1 0.1 2.6 8.2 0.0 3.4 3 0 0 3 3 3 0 CH-like domain in sperm protein EF-hand_6 PF13405.6 RKP02291.1 - 0.12 12.4 2.0 2.8 8.1 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 RKP02291.1 - 0.14 11.7 0.0 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 EF hand Ricin_B_lectin PF00652.22 RKP02292.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain PAP2 PF01569.21 RKP02293.1 - 3.3e-28 98.1 4.9 3.3e-28 98.1 4.9 2.0 2 0 0 2 2 2 1 PAP2 superfamily TPPK_C PF12555.8 RKP02293.1 - 1.3 9.1 6.8 0.45 10.6 0.4 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal FHA PF00498.26 RKP02294.1 - 4.3e-14 52.6 0.0 7.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RKP02294.1 - 7.3e-07 29.4 0.0 0.017 15.4 0.0 2.5 1 1 1 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain PTCB-BRCT PF12738.7 RKP02294.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 RKP02294.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Sec10 PF07393.11 RKP02295.1 - 5.4e-83 279.7 0.0 7.1e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 LRR_8 PF13855.6 RKP02296.1 - 4e-46 154.6 45.4 1.9e-09 37.1 2.8 9.0 2 1 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 RKP02296.1 - 2.3e-37 126.4 52.3 1.1e-05 25.7 2.0 9.9 5 2 6 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP02296.1 - 2.6e-11 42.4 48.4 1.2 10.0 0.1 14.8 17 1 0 17 17 17 5 Leucine Rich Repeat LRR_9 PF14580.6 RKP02296.1 - 1e-06 28.4 26.7 0.00018 21.1 1.6 5.1 1 1 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 RKP02296.1 - 0.00015 21.7 2.5 0.66 10.0 0.1 3.5 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) PDU_like PF15953.5 RKP02296.1 - 0.06 13.4 1.8 6.4 6.8 0.1 2.9 3 0 0 3 3 3 0 Putative propanediol utilisation CSTF_C PF14304.6 RKP02296.1 - 5.8 6.6 9.7 4.1 7.1 0.1 4.3 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal LRR_6 PF13516.6 RKP02296.1 - 6.4 7.1 50.0 6.2 7.1 0.0 11.5 14 0 0 14 14 14 0 Leucine Rich repeat WD40 PF00400.32 RKP02297.1 - 1e-24 86.3 3.2 5.5e-05 23.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02297.1 - 4.6e-14 52.5 0.1 0.031 14.6 0.0 4.6 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKP02297.1 - 0.027 14.1 0.4 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain Mito_carr PF00153.27 RKP02298.1 - 5.6e-40 135.2 12.0 3.7e-17 62.0 0.0 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RKP02298.1 - 0.088 11.9 1.4 4.7 6.3 0.1 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease PX PF00787.24 RKP02299.1 - 1.9e-10 40.7 0.0 3.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 PX domain HSP70 PF00012.20 RKP02300.1 - 9.1e-258 856.4 10.2 1e-257 856.2 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKP02300.1 - 5.8e-18 64.8 0.5 1.2e-16 60.5 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 RKP02300.1 - 0.013 14.5 0.6 0.34 9.8 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 RKP02300.1 - 0.019 15.4 6.9 3.6 8.1 0.3 4.3 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 RKP02300.1 - 0.035 13.3 0.7 1.3 8.2 0.1 2.4 1 1 1 2 2 2 0 StbA protein GTP_EFTU PF00009.27 RKP02301.1 - 1e-37 129.6 0.0 1.2e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKP02301.1 - 2.4e-06 27.6 0.0 1.5e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 RKP02301.1 - 0.0044 16.8 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 RKP02301.1 - 0.0072 16.2 0.1 0.71 9.7 0.0 2.5 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 RKP02301.1 - 0.0096 15.4 0.0 3 7.2 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit cobW PF02492.19 RKP02301.1 - 0.012 15.2 0.1 1.5 8.4 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 RKP02301.1 - 0.025 14.1 0.0 2.7 7.5 0.0 3.0 2 1 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 RKP02301.1 - 0.083 12.7 0.0 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 RKP02301.1 - 0.21 11.3 0.4 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain EloA-BP1 PF15870.5 RKP02302.1 - 3.5e-06 27.4 0.0 7.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ElonginA binding-protein 1 RhoGEF PF00621.20 RKP02303.1 - 1.1e-23 84.5 0.0 1.5e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PGC7_Stella PF15549.6 RKP02303.1 - 0.092 12.7 0.7 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain IQ PF00612.27 RKP02303.1 - 0.56 10.1 3.9 2.2 8.3 3.9 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif GTP_EFTU PF00009.27 RKP02304.1 - 7.3e-54 182.3 0.0 1.1e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RKP02304.1 - 1.6e-41 141.1 0.0 3e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RKP02304.1 - 4e-16 59.2 0.2 1.2e-15 57.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RKP02304.1 - 0.0021 18.1 0.1 0.05 13.7 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 RKP02304.1 - 0.003 17.4 0.3 0.0097 15.8 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 NIF3 PF01784.18 RKP02304.1 - 0.045 13.4 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) AAA_29 PF13555.6 RKP02304.1 - 0.088 12.6 0.3 12 5.7 0.2 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Peptidase_S8 PF00082.22 RKP02307.1 - 1.1e-46 159.5 2.1 1.5e-46 159.1 2.1 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 RKP02307.1 - 3e-05 24.0 1.0 7.6e-05 22.7 0.3 2.2 2 0 0 2 2 2 1 PA domain fn3_5 PF06280.12 RKP02307.1 - 0.0018 19.0 0.0 0.0028 18.3 0.0 1.3 1 0 0 1 1 1 1 Fn3-like domain Cwf_Cwc_15 PF04889.12 RKP02308.1 - 5.8e-42 144.1 0.7 7.7e-42 143.7 0.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein End3 PF12761.7 RKP02308.1 - 0.055 13.6 0.9 0.082 13.1 0.9 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 YL1 PF05764.13 RKP02308.1 - 0.29 11.2 15.0 0.61 10.2 15.0 1.6 1 1 0 1 1 1 0 YL1 nuclear protein AF-4 PF05110.13 RKP02308.1 - 0.79 7.7 9.3 0.96 7.5 9.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Snf7 PF03357.21 RKP02309.1 - 6.2e-32 110.6 8.7 8.1e-32 110.2 8.7 1.2 1 0 0 1 1 1 1 Snf7 Pox_G7 PF05503.12 RKP02309.1 - 0.034 13.1 0.2 0.043 12.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus G7-like DUF3585 PF12130.8 RKP02309.1 - 0.2 11.8 5.2 0.32 11.1 5.2 1.5 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain CheX PF13690.6 RKP02309.1 - 0.96 9.7 3.7 34 4.7 3.7 2.3 1 1 0 1 1 1 0 Chemotaxis phosphatase CheX SWIB PF02201.18 RKP02310.1 - 1.7e-18 66.2 0.0 3.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF1116 PF06545.11 RKP02310.1 - 0.14 11.6 0.2 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) DEAD PF00270.29 RKP02312.1 - 1.1e-49 168.6 0.0 4.9e-49 166.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP02312.1 - 9.1e-30 103.3 0.0 2.8e-29 101.7 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP02312.1 - 0.00053 20.0 0.0 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 RKP02312.1 - 0.0033 16.2 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PGM_PMM_I PF02878.16 RKP02314.1 - 7.8e-36 122.8 0.1 1.2e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RKP02314.1 - 9.9e-28 96.6 0.0 2.6e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RKP02314.1 - 1.6e-15 57.6 0.0 4.1e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 RKP02314.1 - 2.5e-07 30.7 0.0 6.6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4466 PF14725.6 RKP02314.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) tRNA-synt_2 PF00152.20 RKP02315.1 - 7.7e-74 248.6 0.7 9.8e-74 248.2 0.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RKP02315.1 - 0.086 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4471 PF14740.6 RKP02316.1 - 1.9e-41 142.3 0.0 8.2e-40 136.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 RKP02316.1 - 1.2e-11 44.6 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) PP-binding PF00550.25 RKP02317.1 - 4.1e-11 43.1 1.0 5e-11 42.8 1.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Lyase_1 PF00206.20 RKP02318.1 - 1e-22 81.0 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 RKP02318.1 - 5.6e-18 65.3 0.0 2.1e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Gaa1 PF04114.14 RKP02319.1 - 3.5e-82 277.0 0.0 3.3e-81 273.8 0.0 2.2 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component PgaD PF13994.6 RKP02319.1 - 0.072 13.1 0.6 0.37 10.8 0.2 2.4 2 1 0 2 2 2 0 PgaD-like protein NatB_MDM20 PF09797.9 RKP02320.1 - 1.2e-46 159.5 0.0 2.3e-46 158.5 0.0 1.5 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 RKP02320.1 - 0.00076 19.9 1.1 0.00076 19.9 1.1 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP02320.1 - 0.0085 16.3 4.3 1.8 8.8 0.1 3.6 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SUIM_assoc PF16619.5 RKP02320.1 - 0.025 14.6 8.6 0.093 12.8 8.6 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_8 PF13181.6 RKP02320.1 - 0.027 14.7 2.1 6.7 7.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKP02320.1 - 0.18 12.0 8.2 12 6.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02320.1 - 1.9 8.4 9.6 20 5.2 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 RKP02321.1 - 3e-14 53.0 0.0 1.4e-13 50.8 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like UBX PF00789.20 RKP02321.1 - 1.1e-13 51.1 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 RKP02321.1 - 1.7e-12 47.0 0.0 3.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 RKP02321.1 - 0.0014 18.4 0.4 0.0046 16.8 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Syja_N PF02383.18 RKP02322.1 - 7e-71 239.2 0.0 9.4e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 RKP02322.1 - 1.1e-11 44.8 0.1 1.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LSM PF01423.22 RKP02323.1 - 0.00015 21.4 0.0 0.21 11.3 0.0 2.1 1 1 1 2 2 2 2 LSM domain ProRS-C_2 PF09181.10 RKP02323.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Glycos_transf_3 PF00591.21 RKP02324.1 - 1.8e-80 270.2 0.0 2.2e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 RKP02324.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Alba PF01918.21 RKP02325.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 RKP02325.1 - 8.2e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P MAP65_ASE1 PF03999.12 RKP02325.1 - 0.24 10.1 0.8 0.22 10.2 0.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PIN_6 PF17146.4 RKP02326.1 - 2.4e-26 92.0 0.4 4.8e-26 91.1 0.4 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 RKP02326.1 - 1.2e-25 89.5 0.2 2.1e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2072 PF09845.9 RKP02326.1 - 0.22 11.8 0.3 0.5 10.6 0.0 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein CPSase_L_D2 PF02786.17 RKP02327.1 - 9.1e-109 361.9 0.0 5.9e-81 271.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 RKP02327.1 - 2e-45 154.9 0.0 3.7e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 RKP02327.1 - 2.6e-44 150.1 0.0 6.3e-44 148.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 RKP02327.1 - 2.7e-43 147.5 0.0 6e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 RKP02327.1 - 1.5e-39 135.1 0.2 3.4e-39 134.0 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 RKP02327.1 - 2.3e-31 109.0 0.0 4.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 RKP02327.1 - 4.6e-17 62.0 0.0 3e-16 59.4 0.0 2.5 2 1 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 RKP02327.1 - 1.2e-14 54.4 0.2 3.6e-08 33.2 0.1 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 RKP02327.1 - 9.2e-14 51.4 0.1 2e-07 30.8 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 RKP02327.1 - 3.8e-12 46.1 0.2 4.3e-07 29.7 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 RKP02327.1 - 7.5e-05 22.6 0.1 0.008 16.0 0.0 2.6 2 0 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 RKP02327.1 - 0.0003 20.6 0.0 0.042 13.6 0.0 3.3 3 0 0 3 3 3 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 RKP02327.1 - 0.013 15.5 0.2 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain SH3_9 PF14604.6 RKP02329.1 - 1.7e-07 31.0 0.0 3.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP02329.1 - 1.2e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKP02329.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3818 PF12825.7 RKP02330.1 - 9.8e-47 159.6 0.0 1.7e-34 119.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) Serglycin PF04360.12 RKP02330.1 - 0.012 15.5 4.3 0.029 14.3 4.3 1.5 1 0 0 1 1 1 0 Serglycin PXB PF12828.7 RKP02330.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 0 PX-associated AF-4 PF05110.13 RKP02330.1 - 0.028 12.5 1.6 0.048 11.8 1.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LRV PF01816.17 RKP02330.1 - 3.1 8.4 8.0 0.48 10.9 1.2 3.5 2 0 0 2 2 2 0 Leucine rich repeat variant E1-E2_ATPase PF00122.20 RKP02331.1 - 4.8e-48 163.1 5.6 4.8e-48 163.1 5.6 2.9 5 0 0 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 RKP02331.1 - 2e-19 70.7 0.1 4.9e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKP02331.1 - 2.4e-13 49.5 0.0 6.8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKP02331.1 - 0.022 14.5 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP02331.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) TetR_C_6 PF13977.6 RKP02331.1 - 0.26 11.5 2.5 18 5.6 0.1 2.8 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal CM_2 PF01817.21 RKP02332.1 - 0.00045 20.5 1.7 0.15 12.4 0.0 2.6 3 0 0 3 3 3 2 Chorismate mutase type II DUF2939 PF11159.8 RKP02332.1 - 0.013 15.8 1.1 0.027 14.9 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) Pox_E2-like PF04497.12 RKP02332.1 - 0.14 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxviridae protein DUF2057 PF09829.9 RKP02332.1 - 0.18 11.9 0.5 0.28 11.4 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SGS PF05002.15 RKP02333.1 - 5.1e-33 113.0 0.2 9.2e-33 112.2 0.2 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 RKP02333.1 - 7.2e-11 43.0 0.0 1.1e-10 42.4 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF2057 PF09829.9 RKP02333.1 - 0.00084 19.6 1.1 0.0014 18.9 1.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) CTK3_C PF12350.8 RKP02334.1 - 7.9e-10 38.8 2.3 3.2e-09 36.8 2.3 2.0 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 RKP02334.1 - 3.2e-07 30.4 0.0 5.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF5069 PF16798.5 RKP02334.1 - 0.024 14.8 0.0 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5069) CTD_bind PF04818.13 RKP02334.1 - 0.038 14.8 0.0 0.074 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Symplekin_C PF12295.8 RKP02334.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Alg14 PF08660.11 RKP02335.1 - 1.7e-36 125.8 0.0 1.7e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like zf-H2C2_2 PF13465.6 RKP02336.1 - 9.9e-18 63.7 16.8 3.3e-06 27.3 0.3 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 RKP02336.1 - 2.9e-13 49.5 18.4 0.0047 17.3 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02336.1 - 3.7e-12 46.0 16.4 0.0026 18.5 0.3 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKP02336.1 - 3.3e-08 33.6 1.9 0.0033 17.6 0.0 4.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP02336.1 - 7.1e-05 23.1 9.6 0.0028 18.0 0.2 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RKP02336.1 - 0.00029 20.5 22.8 0.004 16.9 0.1 5.4 4 2 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 RKP02336.1 - 0.006 16.9 6.1 0.17 12.2 4.5 2.5 1 1 2 3 3 3 3 C2H2-type zinc ribbon Elf1 PF05129.13 RKP02336.1 - 0.011 15.8 1.9 0.016 15.2 1.1 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.12 RKP02336.1 - 0.011 16.0 14.1 0.085 13.2 1.7 3.0 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.20 RKP02336.1 - 0.052 13.3 1.4 0.052 13.3 1.4 2.6 3 1 0 3 3 3 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 RKP02336.1 - 0.08 13.0 7.5 1.2 9.3 3.3 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_9 PF16293.5 RKP02336.1 - 0.11 12.3 4.8 0.75 9.7 0.1 3.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 RKP02336.1 - 0.37 11.3 10.2 11 6.6 0.4 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 RKP02336.1 - 0.75 9.9 17.0 2 8.5 1.5 4.0 5 0 0 5 5 5 0 C2H2-type zinc finger FOXP-CC PF16159.5 RKP02336.1 - 0.87 10.3 4.1 0.9 10.2 1.5 2.1 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 RKP02336.1 - 0.88 9.9 8.0 3.6 8.0 0.3 3.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 RKP02336.1 - 2.5 8.6 8.4 0.18 12.2 1.5 2.4 2 2 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D RNA_pol_Rpb1_5 PF04998.17 RKP02337.1 - 3.2e-95 318.6 0.0 4.5e-95 318.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 RKP02337.1 - 1.4e-62 210.8 0.0 2.5e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 RKP02337.1 - 1.1e-29 103.4 0.0 2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 RKP02337.1 - 2e-29 102.9 0.0 6.1e-24 84.9 0.0 3.2 3 0 0 3 3 3 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 RKP02337.1 - 8.2e-22 77.2 0.0 1.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Pkinase PF00069.25 RKP02338.1 - 1.7e-24 86.7 0.0 2.2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02338.1 - 1.3e-12 47.6 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP02338.1 - 3.9e-11 42.4 0.0 6.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKP02338.1 - 0.00027 20.9 2.9 0.0022 17.9 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RKP02338.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNA_pol_Rpb2_6 PF00562.28 RKP02339.1 - 7e-111 371.0 0.0 1.7e-110 369.8 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RKP02339.1 - 3.8e-35 121.2 0.0 6.1e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 RKP02339.1 - 5.1e-28 97.1 0.0 1.4e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 RKP02339.1 - 5.8e-20 71.5 0.3 8.3e-19 67.8 0.2 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 RKP02339.1 - 2.6e-19 69.6 0.0 4.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 RKP02339.1 - 5.5e-19 67.9 0.0 1.9e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain Thioredoxin PF00085.20 RKP02340.1 - 3.6e-06 26.9 0.1 5e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 RKP02340.1 - 0.016 15.0 1.0 0.021 14.6 1.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 LRR_4 PF12799.7 RKP02341.1 - 1.2e-17 63.7 10.9 5.6e-07 29.8 2.1 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP02341.1 - 4.2e-11 42.4 7.4 0.0021 17.8 0.0 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RKP02341.1 - 6e-09 35.6 1.5 5.4e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RKP02341.1 - 0.0065 16.9 6.3 12 6.9 0.2 4.6 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 RKP02341.1 - 0.076 13.1 1.9 24 5.3 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich repeat FNIP PF05725.12 RKP02341.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 FNIP Repeat Na_H_antiporter PF03553.14 RKP02342.1 - 0.076 12.2 2.3 0.11 11.8 2.3 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter family TFIIA PF03153.13 RKP02342.1 - 0.35 10.8 13.0 0.4 10.6 13.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LIM PF00412.22 RKP02343.1 - 1.8e-31 108.2 29.9 2.1e-12 47.0 3.6 3.2 3 0 0 3 3 3 3 LIM domain zf-ribbon_3 PF13248.6 RKP02343.1 - 0.00072 18.9 3.8 0.9 9.0 0.0 4.7 4 0 0 4 4 4 2 zinc-ribbon domain DZR PF12773.7 RKP02343.1 - 0.0031 17.5 24.4 3.3 7.8 1.0 4.7 1 1 1 2 2 2 1 Double zinc ribbon zf-B_box PF00643.24 RKP02343.1 - 0.058 13.6 1.1 0.058 13.6 1.1 5.7 6 2 1 7 7 7 0 B-box zinc finger zf_UBZ PF18439.1 RKP02343.1 - 0.084 12.5 0.6 0.084 12.5 0.6 5.6 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger YsaB PF13983.6 RKP02343.1 - 0.26 11.6 2.4 18 5.7 0.2 2.6 2 0 0 2 2 2 0 YsaB-like lipoprotein FUR PF01475.19 RKP02343.1 - 0.43 10.7 1.6 26 5.0 0.1 2.4 2 0 0 2 2 2 0 Ferric uptake regulator family E1-E2_ATPase PF00122.20 RKP02344.1 - 7.5e-45 152.7 0.2 1.9e-44 151.3 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RKP02344.1 - 1.6e-15 58.0 0.7 2e-08 34.8 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP02344.1 - 6.9e-15 54.9 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 RKP02344.1 - 2.4e-14 53.5 23.0 2.9e-13 49.9 7.1 3.1 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 RKP02344.1 - 2.1e-05 24.1 0.0 4.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKP02344.1 - 0.0025 17.6 2.0 0.04 13.6 1.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 RKP02345.1 - 7.8e-31 105.7 17.7 2e-07 31.6 0.3 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02345.1 - 2.2e-15 56.7 0.1 0.0024 18.1 0.1 5.6 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 RKP02345.1 - 2.9e-08 33.1 1.5 2.9e-08 33.1 1.5 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 RKP02345.1 - 0.0069 15.4 0.0 6.3 5.7 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-HIT PF04438.16 RKP02346.1 - 7e-07 29.0 9.3 1.2e-06 28.2 9.3 1.4 1 0 0 1 1 1 1 HIT zinc finger Ribosomal_L32p PF01783.23 RKP02346.1 - 0.13 12.5 6.9 2.5 8.5 0.4 2.9 2 1 1 3 3 3 0 Ribosomal L32p protein family DUF35_N PF12172.8 RKP02346.1 - 0.17 11.8 0.4 0.17 11.8 0.4 2.8 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pro_isomerase PF00160.21 RKP02347.1 - 1.1e-41 142.7 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_60s PF00428.19 RKP02347.1 - 1.4 9.5 11.9 2.8 8.6 11.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Adeno_PV PF03910.13 RKP02347.1 - 9.3 4.8 7.4 12 4.5 7.4 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV SnoaL_2 PF12680.7 RKP02348.1 - 0.047 14.3 0.2 4.7 7.9 0.0 2.6 2 1 0 2 2 2 0 SnoaL-like domain Importin_rep_4 PF18808.1 RKP02349.1 - 2.1e-25 88.8 0.6 4e-24 84.7 0.0 3.3 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 RKP02349.1 - 6.5e-16 57.1 23.9 0.00033 20.7 0.0 10.9 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 RKP02349.1 - 5.1e-15 55.6 18.9 4.9e-10 39.7 0.0 7.7 8 3 2 10 10 9 4 HEAT repeats HEAT_EZ PF13513.6 RKP02349.1 - 4.1e-09 36.7 24.2 4.7e-07 30.2 0.0 9.1 10 1 1 11 11 8 1 HEAT-like repeat DUF3385 PF11865.8 RKP02349.1 - 1.4e-08 34.8 0.3 0.028 14.3 0.0 5.5 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) Importin_rep_6 PF18829.1 RKP02349.1 - 1.4e-07 31.6 2.5 1.8e-07 31.3 0.0 2.6 3 0 0 3 3 1 1 Importin repeat 6 Adaptin_N PF01602.20 RKP02349.1 - 2.4e-07 29.7 1.5 0.00022 19.9 0.0 2.8 2 0 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.8 RKP02349.1 - 3.1e-07 30.2 0.7 0.39 10.3 0.0 6.3 7 2 0 7 7 7 2 CLASP N terminal Cnd1 PF12717.7 RKP02349.1 - 1.8e-06 28.1 0.1 0.009 16.1 0.0 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RKP02349.1 - 4.5e-06 27.2 0.0 0.01 16.4 0.0 5.5 3 2 3 6 6 6 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 RKP02349.1 - 0.00019 21.2 1.5 1.1 9.0 0.0 4.8 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 RKP02349.1 - 0.00053 20.1 1.5 12 6.1 0.0 5.5 5 1 1 6 6 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 RKP02349.1 - 0.0036 17.3 11.9 5.1 7.3 0.1 7.4 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 RKP02349.1 - 0.0074 16.0 0.9 6.6 6.4 0.0 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.14 RKP02349.1 - 0.031 13.5 0.2 4.8 6.4 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H Cohesin_HEAT PF12765.7 RKP02349.1 - 0.084 13.2 0.0 0.75 10.2 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Yip1 PF04893.17 RKP02350.1 - 3.1e-09 36.8 11.2 4.9e-09 36.1 11.2 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 RKP02350.1 - 6.1 5.0 10.4 7.5 4.7 10.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Vta1 PF04652.16 RKP02351.1 - 9.7e-49 165.1 3.8 1.1e-48 164.9 3.8 1.0 1 0 0 1 1 1 1 Vta1 like DUF2019 PF09450.10 RKP02351.1 - 0.036 14.0 0.2 0.083 12.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Peptidase_C48 PF02902.19 RKP02352.1 - 1.1e-34 120.2 0.0 1.3e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 RKP02352.1 - 0.03 13.0 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase PPR PF01535.20 RKP02354.1 - 0.0063 16.7 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 2 PPR repeat TPH PF13868.6 RKP02355.1 - 6.4e-62 209.1 128.5 6.4e-62 209.1 128.5 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Pro_isomerase PF00160.21 RKP02356.1 - 2.1e-41 141.8 0.0 2.3e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 RKP02356.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Mitoc_mL59 PF18126.1 RKP02357.1 - 0.00018 21.8 0.1 0.00024 21.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Clathrin_lg_ch PF01086.17 RKP02358.1 - 1.7e-30 106.8 1.0 3.6e-18 66.5 0.0 3.1 3 0 0 3 3 3 3 Clathrin light chain RNA_polI_A34 PF08208.11 RKP02358.1 - 0.012 15.7 0.2 0.023 14.8 0.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 rve_3 PF13683.6 RKP02358.1 - 0.064 13.0 0.5 0.44 10.3 0.3 2.1 2 0 0 2 2 2 0 Integrase core domain YqhG PF11079.8 RKP02358.1 - 0.88 8.5 2.2 1.2 8.0 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Pkinase PF00069.25 RKP02359.1 - 5.3e-66 222.7 0.0 6.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02359.1 - 2.9e-42 144.8 0.0 3.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02359.1 - 3e-08 33.3 0.1 2.9e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Kinase-like PIP49_C PF12260.8 RKP02359.1 - 0.023 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_C PF00433.24 RKP02359.1 - 0.024 15.4 1.1 0.042 14.6 1.1 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 RKP02359.1 - 0.032 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RKP02359.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Amino_oxidase PF01593.24 RKP02360.1 - 4.7e-35 121.7 3.9 6.1e-35 121.4 3.9 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 RKP02360.1 - 9.1e-12 45.0 7.1 6.9e-10 39.0 7.1 2.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RKP02360.1 - 0.00077 19.1 14.2 0.0066 16.1 14.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RKP02360.1 - 0.011 15.0 1.3 0.018 14.3 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 RKP02360.1 - 0.041 12.7 0.2 0.083 11.7 0.2 1.4 1 0 0 1 1 1 0 MCRA family SH3_16 PF18348.1 RKP02360.1 - 0.069 13.0 0.6 0.21 11.4 0.6 1.9 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain NAD_binding_9 PF13454.6 RKP02360.1 - 0.13 12.3 1.9 0.63 10.0 0.2 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 RKP02360.1 - 0.32 11.6 1.0 0.58 10.8 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0183 PF03676.14 RKP02362.1 - 1.7e-58 198.8 0.0 9.9e-28 97.5 0.0 3.3 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) RhoGAP PF00620.27 RKP02363.1 - 1.3e-35 122.5 0.0 2.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF356 PF04009.12 RKP02364.1 - 0.015 15.6 0.3 0.023 14.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF356) Nucleoporin2 PF04096.14 RKP02365.1 - 6.4e-44 149.7 0.0 1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 RKP02365.1 - 9.7e-38 129.9 0.2 1.7e-37 129.2 0.2 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 RKP02365.1 - 3.2e-06 27.9 62.5 6.2e-05 23.8 25.3 13.3 6 3 8 14 14 14 6 Nucleoporin FG repeat region Nup84_Nup100 PF04121.13 RKP02365.1 - 0.46 8.5 2.8 3.9 5.4 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore protein 84 / 107 TM231 PF10149.9 RKP02366.1 - 9.1e-08 31.8 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 2 Transmembrane protein 231 Thioredoxin PF00085.20 RKP02368.1 - 8.4e-46 154.2 0.3 1.1e-22 80.0 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 RKP02368.1 - 1.4e-30 106.6 0.0 6e-26 91.5 0.1 2.9 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RKP02368.1 - 1.1e-06 28.7 0.0 0.024 14.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RKP02368.1 - 1e-05 25.9 0.2 0.48 10.9 0.0 3.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RKP02368.1 - 0.00042 20.6 0.0 1 9.7 0.0 3.9 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 RKP02368.1 - 0.0006 19.7 0.2 0.28 11.1 0.0 3.2 4 0 0 4 4 4 1 AhpC/TSA family Calsequestrin PF01216.17 RKP02368.1 - 0.003 16.6 0.1 0.031 13.3 0.0 2.2 2 1 0 2 2 2 1 Calsequestrin ERp29_N PF07912.13 RKP02368.1 - 0.0089 16.2 0.5 1.2 9.3 0.0 3.8 4 1 1 5 5 5 1 ERp29, N-terminal domain TraF PF13728.6 RKP02368.1 - 0.015 15.1 0.0 4.7 7.0 0.0 3.0 3 1 0 3 3 3 0 F plasmid transfer operon protein DUF2718 PF10918.8 RKP02368.1 - 0.061 13.8 0.4 0.15 12.6 0.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2718) Thioredoxin_9 PF14595.6 RKP02368.1 - 0.08 12.7 0.2 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin DUF4232 PF14016.6 RKP02368.1 - 0.11 12.6 0.8 4.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) Glyco_trans_1_3 PF13528.6 RKP02369.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Peptidase_C2 PF00648.21 RKP02370.1 - 2.8e-09 36.4 0.0 6.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease TPPII_N PF12583.8 RKP02370.1 - 0.0074 16.9 1.1 0.0074 16.9 1.1 15.1 13 2 3 16 16 16 2 Tripeptidyl peptidase II N terminal Ccdc124 PF06244.12 RKP02371.1 - 1.1e-29 103.5 19.1 8e-29 100.8 19.1 2.0 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 RKP02371.1 - 0.0069 16.8 0.7 0.0069 16.8 0.7 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box DUF3889 PF13028.6 RKP02371.1 - 0.013 15.4 0.6 0.013 15.4 0.6 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3889) MAJIN PF15077.6 RKP02371.1 - 3.7 7.3 7.8 6.3 6.5 7.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein ABC_membrane PF00664.23 RKP02372.1 - 1.7e-68 231.3 24.5 1.1e-34 120.3 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKP02372.1 - 1.1e-49 168.5 0.0 9.8e-28 97.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKP02372.1 - 1.7e-08 34.2 0.5 0.11 12.0 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RKP02372.1 - 5.1e-08 32.5 0.2 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 RKP02372.1 - 2.6e-07 31.0 0.7 0.025 14.7 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 RKP02372.1 - 2.9e-07 30.6 0.9 0.013 15.6 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RKP02372.1 - 3.2e-07 30.5 2.4 0.52 10.1 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 RKP02372.1 - 4e-07 30.6 0.6 0.0023 18.3 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 RKP02372.1 - 4e-07 30.8 0.0 0.0014 19.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 RKP02372.1 - 5.6e-06 26.4 0.0 0.0053 16.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 RKP02372.1 - 0.00015 20.9 0.0 0.17 10.9 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 RKP02372.1 - 0.00025 21.4 0.4 0.84 9.9 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RKP02372.1 - 0.00031 20.5 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RKP02372.1 - 0.00081 19.2 0.1 0.77 9.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 RKP02372.1 - 0.0032 17.1 1.2 1.8 8.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 RKP02372.1 - 0.0051 16.3 0.2 2.4 7.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 RKP02372.1 - 0.0056 16.8 1.1 0.089 12.8 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 RKP02372.1 - 0.0094 16.5 0.1 2.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RKP02372.1 - 0.016 14.9 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 RKP02372.1 - 0.017 14.1 0.2 2.5 7.0 0.2 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 RKP02372.1 - 0.019 14.3 0.2 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 RKP02372.1 - 0.022 13.7 0.6 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 RKP02372.1 - 0.031 13.6 0.1 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 RKP02372.1 - 0.057 12.6 0.3 4 6.5 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain Pox_A32 PF04665.12 RKP02372.1 - 0.088 12.3 0.3 8.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 RKP02372.1 - 0.098 12.6 2.1 8.2 6.3 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 RKP02372.1 - 0.099 12.7 0.2 2.5 8.2 0.2 2.7 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 RKP02372.1 - 0.1 12.8 0.4 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RKP02372.1 - 0.19 11.7 1.2 11 5.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 RKP02372.1 - 0.19 12.1 0.2 36 4.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_27 PF13514.6 RKP02372.1 - 0.2 11.2 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RKP02372.1 - 0.2 11.7 0.6 25 4.9 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RKP02372.1 - 0.63 10.2 2.2 19 5.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain ATP_bind_3 PF01171.20 RKP02373.1 - 3.9e-17 62.6 0.0 5.5e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 RKP02373.1 - 6.7e-17 60.7 2.3 6.7e-17 60.7 2.3 3.3 4 0 0 4 4 4 1 Zinc-ribbon Closter_coat PF01785.17 RKP02373.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Closterovirus coat protein tRNA_Me_trans PF03054.16 RKP02373.1 - 0.03 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase HECT PF00632.25 RKP02374.1 - 6.8e-97 324.6 0.1 9e-97 324.2 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.7 RKP02376.1 - 2.6e-28 98.3 7.8 1e-20 74.0 2.2 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RKP02376.1 - 1.1e-13 51.1 2.8 7e-09 35.8 1.4 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP02376.1 - 3.8e-07 30.3 5.0 4.3e-06 26.9 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RKP02376.1 - 0.015 15.3 1.0 0.069 13.2 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 RKP02376.1 - 0.044 14.6 11.9 0.15 13.0 0.1 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger GCFC PF07842.12 RKP02379.1 - 3.8e-17 62.8 9.0 1.3e-15 57.7 1.9 2.4 3 0 0 3 3 3 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 RKP02379.1 - 1.9e-11 43.6 0.6 1.9e-11 43.6 0.6 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 RKP02379.1 - 5.4e-06 26.4 0.1 1.1e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 G-patch domain GRIP PF01465.20 RKP02380.1 - 6.8e-11 41.9 0.0 2.2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 GRIP domain TPR_MLP1_2 PF07926.12 RKP02380.1 - 0.014 15.5 10.8 0.014 15.5 10.8 10.1 1 1 8 10 10 10 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 RKP02380.1 - 1.3 9.5 6.5 61 4.1 0.1 5.6 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) LURAP PF14854.6 RKP02381.1 - 0.009 16.0 0.1 4.7 7.2 0.0 3.2 3 0 0 3 3 3 2 Leucine rich adaptor protein BST2 PF16716.5 RKP02381.1 - 0.22 12.1 0.1 0.22 12.1 0.1 6.9 8 0 0 8 8 8 0 Bone marrow stromal antigen 2 MCC-bdg_PDZ PF10506.9 RKP02381.1 - 3 7.9 10.2 0.15 12.1 0.9 3.7 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA PF00004.29 RKP02383.1 - 2.6e-42 144.4 0.0 3.3e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 RKP02383.1 - 2.3e-07 30.9 0.0 3.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_2 PF07724.14 RKP02383.1 - 4.4e-06 26.9 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKP02383.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP02383.1 - 2.2e-05 24.8 0.3 0.02 15.2 0.1 2.1 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RKP02383.1 - 4.3e-05 23.3 0.0 5.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 RKP02383.1 - 5.4e-05 23.6 0.1 0.0004 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RKP02383.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RKP02383.1 - 0.00065 19.1 0.0 0.00072 18.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 RKP02383.1 - 0.0012 18.7 0.1 0.18 11.6 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 RKP02383.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 RKP02383.1 - 0.0015 18.5 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKP02383.1 - 0.0018 17.9 0.2 0.014 15.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain SRP54 PF00448.22 RKP02383.1 - 0.0028 17.3 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 RKP02383.1 - 0.0032 17.8 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 RKP02383.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 RKP02383.1 - 0.0043 16.8 0.0 0.019 14.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RKP02383.1 - 0.0044 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 RKP02383.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RKP02383.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 RKP02383.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 RKP02383.1 - 0.021 15.0 0.0 0.035 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 RKP02383.1 - 0.029 13.8 0.0 5.3 6.4 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 RKP02383.1 - 0.037 14.6 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RKP02383.1 - 0.042 13.6 0.1 0.059 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RKP02383.1 - 0.053 13.8 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKP02383.1 - 0.063 12.6 0.1 0.22 10.9 0.1 1.7 1 1 0 1 1 1 0 KaiC Terminase_6 PF03237.15 RKP02383.1 - 0.073 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family AAA_19 PF13245.6 RKP02383.1 - 0.09 13.1 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RKP02383.1 - 0.092 12.7 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RKP02383.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKP02383.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 RKP02383.1 - 0.22 11.3 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein PIF1 PF05970.14 RKP02383.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase TRM13 PF05206.14 RKP02385.1 - 7.7e-63 212.5 0.0 1e-62 212.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 RKP02385.1 - 7.9e-07 28.9 0.2 7.9e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 RKP02385.1 - 0.062 13.3 6.2 0.33 10.9 6.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain MutS_V PF00488.21 RKP02386.1 - 2.4e-72 242.9 0.0 5.8e-72 241.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKP02386.1 - 4.5e-31 108.6 0.4 7.7e-31 107.8 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 RKP02386.1 - 4.9e-30 104.1 0.0 1.2e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 RKP02386.1 - 1e-10 42.0 0.0 2.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RKP02386.1 - 4e-09 36.7 0.0 9.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV LPMO_10 PF03067.15 RKP02389.1 - 4.2e-10 40.6 0.6 3.2e-09 37.7 0.0 2.5 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Metallothi_Euk2 PF12809.7 RKP02389.1 - 1.6 9.0 6.1 2.8 8.3 4.2 2.1 2 0 0 2 2 2 0 Eukaryotic metallothionein TRAM_LAG1_CLN8 PF03798.16 RKP02390.1 - 1.2e-32 113.3 17.8 1.6e-32 112.9 17.8 1.2 1 0 0 1 1 1 1 TLC domain BRCT_2 PF16589.5 RKP02391.1 - 1.6e-05 25.2 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 RKP02391.1 - 0.00092 19.4 0.2 0.0017 18.5 0.2 1.4 1 0 0 1 1 1 1 Rap1 Myb domain Ham1p_like PF01725.16 RKP02392.1 - 9.7e-52 175.6 0.0 1.1e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RRM_1 PF00076.22 RKP02394.1 - 4.1e-30 103.4 0.0 2.6e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 RKP02394.1 - 0.00086 18.9 0.1 0.052 13.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RRM_occluded PF16842.5 RKP02394.1 - 0.067 13.1 0.0 4 7.4 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 RKP02394.1 - 0.11 12.6 0.0 0.68 10.1 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 RKP02394.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd2 PF05786.14 RKP02394.1 - 0.55 8.8 5.6 0.76 8.4 5.6 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 EPL1 PF10513.9 RKP02395.1 - 1.2e-14 55.0 0.1 1.2e-14 55.0 0.1 4.7 4 0 0 4 4 4 2 Enhancer of polycomb-like SUI1 PF01253.22 RKP02396.1 - 2.5e-19 69.5 0.4 4.1e-19 68.9 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 PKI PF02827.16 RKP02396.1 - 0.26 11.5 1.4 0.63 10.3 1.4 1.6 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Ribosomal_S17e PF00833.18 RKP02397.1 - 1.4e-60 202.6 0.2 1.6e-60 202.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Phage-MuB_C PF09077.11 RKP02397.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Mu B transposition protein, C terminal IpaB_EvcA PF03278.13 RKP02397.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 IpaB/EvcA family Pro_isomerase PF00160.21 RKP02398.1 - 1.7e-26 93.4 0.0 3.2e-26 92.5 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 RKP02398.1 - 1.2e-13 50.7 0.0 1.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKP02398.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UBP PF02148.19 RKP02399.1 - 2.6e-10 40.5 1.4 4.7e-10 39.7 1.4 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 RKP02399.1 - 2.2e-06 27.4 0.0 0.00028 20.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF674 PF05056.12 RKP02399.1 - 0.28 10.0 0.0 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) zf-CXXC PF02008.20 RKP02399.1 - 0.32 11.1 2.5 0.52 10.4 2.5 1.2 1 0 0 1 1 1 0 CXXC zinc finger domain DUF846 PF05832.12 RKP02400.1 - 2e-53 180.2 11.2 2.2e-53 180.0 11.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Xpo1 PF08389.12 RKP02401.1 - 6.3e-24 84.7 0.8 5e-22 78.6 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 RKP02401.1 - 0.0001 22.1 0.1 0.001 18.9 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF896 PF05979.12 RKP02401.1 - 0.0014 18.4 0.1 0.0051 16.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF896) DUF3361 PF11841.8 RKP02401.1 - 0.1 12.5 0.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) La PF05383.17 RKP02402.1 - 2.4e-23 82.0 0.0 4.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 RKP02402.1 - 0.00014 21.6 0.1 0.0012 18.6 0.1 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP02402.1 - 0.022 14.9 0.0 0.61 10.2 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif SPATA3 PF15662.5 RKP02402.1 - 0.2 12.3 7.4 0.31 11.6 6.5 1.7 1 1 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF243 PF03103.17 RKP02402.1 - 1.8 8.9 5.0 2.2 8.7 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF243) SIR2 PF02146.17 RKP02404.1 - 1.9e-64 216.9 0.0 2.3e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RKP02404.1 - 0.00066 19.4 0.1 0.66 9.7 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 RKP02404.1 - 0.007 16.2 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Romo1 PF10247.9 RKP02405.1 - 8.7e-19 67.7 6.4 1.1e-18 67.3 6.4 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 IDO PF01231.18 RKP02406.1 - 9.8e-108 360.7 0.0 2.4e-107 359.5 0.0 1.5 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase SH3_9 PF14604.6 RKP02407.1 - 7.1e-08 32.2 0.1 1.4e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 RKP02407.1 - 1.7e-05 24.8 0.1 3.1e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 RKP02407.1 - 4.5e-05 23.0 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKP02407.1 - 0.0072 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 RKP02407.1 - 0.023 15.1 0.1 0.037 14.5 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNARE_assoc PF09335.11 RKP02408.1 - 6.5e-08 33.1 2.2 6.5e-08 33.1 2.2 3.8 3 1 1 4 4 4 1 SNARE associated Golgi protein Dynein_light PF01221.18 RKP02409.1 - 1.3e-41 140.8 0.8 1.4e-41 140.6 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Galactosyl_T PF01762.21 RKP02410.1 - 1e-10 41.8 0.1 1.8e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 Galactosyltransferase DUF2612 PF11041.8 RKP02410.1 - 0.03 14.2 0.1 0.068 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2612) Fringe PF02434.16 RKP02410.1 - 0.13 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Fringe-like DUF4042 PF13251.6 RKP02411.1 - 4.6e-05 23.2 1.4 0.54 9.9 0.1 4.4 4 1 0 4 4 4 2 Domain of unknown function (DUF4042) AC_N PF16214.5 RKP02411.1 - 0.1 11.7 0.7 0.34 10.0 0.7 1.9 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CPBP PF02517.16 RKP02412.1 - 1.8e-17 63.4 6.1 1.8e-17 63.4 6.1 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Metallophos PF00149.28 RKP02413.1 - 4.8e-39 135.0 0.2 6.4e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKP02413.1 - 0.0002 21.8 0.7 0.00041 20.7 0.7 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 RKP02413.1 - 0.12 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain FERM_f0 PF16511.5 RKP02415.1 - 0.00012 22.4 0.0 0.14 12.5 0.0 2.7 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM PI3K_rbd PF00794.18 RKP02415.1 - 0.0013 18.9 0.0 0.079 13.1 0.0 3.0 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain YukD PF08817.10 RKP02415.1 - 0.068 13.9 0.0 2.2 9.0 0.0 3.1 4 0 0 4 4 4 0 WXG100 protein secretion system (Wss), protein YukD RasGEF PF00617.19 RKP02416.1 - 2.9e-49 167.7 0.0 3.5e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain GHMP_kinases_N PF00288.26 RKP02417.1 - 2.8e-11 43.5 0.9 2.8e-11 43.5 0.9 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RKP02417.1 - 1.3e-08 35.1 0.2 1.3e-08 35.1 0.2 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 RKP02417.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Galactokinase galactose-binding signature FRG1 PF06229.12 RKP02417.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 FRG1-like domain RhoGEF PF00621.20 RKP02418.1 - 9.7e-33 113.9 0.0 1.4e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FANCI_S4 PF14678.6 RKP02418.1 - 4.2e-07 29.4 0.0 6.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_S1 PF14675.6 RKP02418.1 - 0.0003 20.4 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 FANCI solenoid 1 DUF4611 PF15387.6 RKP02418.1 - 0.22 11.8 0.0 0.22 11.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 RKP02418.1 - 0.26 9.4 1.1 18 3.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi RabGAP-TBC PF00566.18 RKP02419.1 - 2.4e-52 177.7 0.0 3.5e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mto2_bdg PF12808.7 RKP02419.1 - 0.15 12.4 1.6 1.6 9.1 0.6 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Antimicrobial14 PF08109.11 RKP02419.1 - 0.21 11.6 0.1 0.57 10.3 0.0 1.7 2 0 0 2 2 2 0 Lactocin 705 family YL1 PF05764.13 RKP02420.1 - 0.0049 17.0 8.3 0.0049 17.0 8.3 1.6 2 0 0 2 2 2 1 YL1 nuclear protein RNA_pol_3_Rpc31 PF11705.8 RKP02420.1 - 0.076 13.3 10.4 0.2 11.9 10.4 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 RKP02420.1 - 0.56 9.6 7.3 0.91 8.9 7.3 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 RKP02420.1 - 3.6 5.6 17.5 6 4.8 17.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 RKP02420.1 - 5.4 6.2 11.3 10 5.3 11.3 1.4 1 0 0 1 1 1 0 NOA36 protein DUF5089 PF17002.5 RKP02421.1 - 5.6e-06 26.4 8.8 0.00033 20.6 8.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 RKP02421.1 - 0.029 14.6 6.0 1.8 8.9 0.5 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Pox_H7 PF04787.12 RKP02421.1 - 0.087 13.3 0.2 0.16 12.5 0.2 1.4 1 0 0 1 1 1 0 Late protein H7 TMF_TATA_bd PF12325.8 RKP02421.1 - 0.51 10.6 15.0 0.15 12.3 2.9 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding MtrG PF04210.13 RKP02421.1 - 1.2 9.0 5.2 5.4 7.0 0.1 2.9 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Efg1 PF10153.9 RKP02421.1 - 2 8.8 7.7 5 7.5 5.7 2.4 1 1 1 2 2 2 0 rRNA-processing protein Efg1 Snapin_Pallidin PF14712.6 RKP02421.1 - 3.8 8.0 13.2 0.85 10.1 0.9 2.5 3 0 0 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.12 RKP02421.1 - 4.4 7.8 5.4 12 6.5 0.5 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KH_1 PF00013.29 RKP02422.1 - 4.6e-42 141.7 7.6 4.4e-15 55.2 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RKP02422.1 - 1.9e-15 56.4 4.9 0.0002 21.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RKP02422.1 - 1.8e-08 34.1 1.8 0.15 12.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 RKP02422.1 - 0.0047 17.0 7.8 1 9.5 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 RKP02422.1 - 0.12 12.4 0.0 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 KH-like RNA-binding domain DUF3739 PF12545.8 RKP02423.1 - 5.6 7.5 8.8 0.29 11.6 1.1 2.8 3 1 1 4 4 4 0 Filamentous haemagglutinin family outer membrane protein SIS PF01380.22 RKP02425.1 - 2e-58 195.9 0.2 8.1e-32 109.8 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 RKP02425.1 - 1.3e-16 61.0 0.0 2.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RKP02425.1 - 1.2e-12 47.8 0.0 3.3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RKP02425.1 - 0.00012 21.1 0.1 0.0002 20.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RKP02425.1 - 0.079 13.0 0.0 0.34 10.9 0.0 2.1 1 1 1 2 2 2 0 SIS domain Peroxin-13_N PF04088.13 RKP02426.1 - 3.2e-33 115.0 1.5 4.8e-33 114.5 1.5 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 RKP02426.1 - 2.5e-09 36.8 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP02426.1 - 1e-07 31.4 0.0 0.0012 18.4 0.0 2.6 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 RKP02426.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Metallophos PF00149.28 RKP02427.1 - 5.1e-38 131.6 0.0 7.9e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 RKP02427.1 - 0.0013 19.0 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region DUF5378 PF17349.2 RKP02427.1 - 0.056 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Arm PF00514.23 RKP02428.1 - 0.0024 17.8 3.5 0.0069 16.4 1.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RKP02428.1 - 0.76 10.2 4.3 0.84 10.1 0.6 3.3 2 0 0 2 2 2 0 HEAT repeat DUF3446 PF11928.8 RKP02428.1 - 10 6.5 14.2 27 5.2 0.3 4.7 3 1 1 4 4 4 0 Early growth response N-terminal domain LIM PF00412.22 RKP02429.1 - 7e-16 58.2 23.9 2.8e-07 30.7 2.9 5.0 4 2 0 4 4 4 3 LIM domain Mut7-C PF01927.16 RKP02429.1 - 0.092 12.8 13.9 0.7 10.0 0.1 3.8 2 1 1 3 3 3 0 Mut7-C RNAse domain DUF2614 PF11023.8 RKP02429.1 - 2.6 8.2 5.2 0.82 9.8 0.1 2.7 3 0 0 3 3 3 0 Zinc-ribbon containing domain FSA_C PF10479.9 RKP02429.1 - 8.5 4.4 6.6 12 3.9 6.6 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ABC_membrane PF00664.23 RKP02430.1 - 5.9e-63 213.1 17.3 2.7e-35 122.4 1.1 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKP02430.1 - 5.1e-46 156.6 0.0 3e-25 89.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKP02430.1 - 3.1e-08 33.3 0.3 0.0092 15.4 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RKP02430.1 - 1.8e-06 27.6 0.1 0.033 13.9 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 RKP02430.1 - 2.3e-05 25.0 0.0 0.0086 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 RKP02430.1 - 4.9e-05 23.5 0.1 0.33 11.0 0.0 2.8 3 0 0 3 3 3 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 RKP02430.1 - 8.2e-05 22.6 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 RKP02430.1 - 0.00018 21.2 0.0 0.075 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 RKP02430.1 - 0.00022 21.3 0.0 0.47 10.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 RKP02430.1 - 0.00029 20.8 0.0 3.5 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 RKP02430.1 - 0.00029 20.0 0.0 0.75 8.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 RKP02430.1 - 0.001 19.5 0.6 2.2 8.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 RKP02430.1 - 0.0016 18.7 0.0 1.9 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 RKP02430.1 - 0.003 16.6 0.1 1.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 RKP02430.1 - 0.0038 16.5 0.0 1 8.6 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin FtsK_SpoIIIE PF01580.18 RKP02430.1 - 0.0059 16.0 0.1 0.77 9.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family CbiA PF01656.23 RKP02430.1 - 0.0083 16.2 0.0 8 6.5 0.0 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 RKP02430.1 - 0.014 15.1 0.1 3.1 7.5 0.0 3.1 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 RKP02430.1 - 0.026 14.7 0.0 2.6 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 RKP02430.1 - 0.027 14.5 0.3 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 RKP02430.1 - 0.034 14.4 0.1 1.7 9.0 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2917 PF11142.8 RKP02430.1 - 0.099 12.1 0.3 0.37 10.2 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) AAA_30 PF13604.6 RKP02430.1 - 0.1 12.3 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKP02430.1 - 0.12 12.1 0.1 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 RKP02430.1 - 0.17 10.8 0.2 0.87 8.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.13 RKP02430.1 - 0.2 10.8 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_membrane PF00664.23 RKP02431.1 - 3.9e-38 131.7 5.7 5e-38 131.3 5.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKP02431.1 - 7.5e-34 117.2 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RKP02431.1 - 6.7e-07 29.0 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 RKP02431.1 - 4.2e-05 23.8 0.1 0.00027 21.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP02431.1 - 7.2e-05 23.2 0.0 0.00019 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RKP02431.1 - 0.00085 19.0 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 RKP02431.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 RKP02431.1 - 0.0022 17.8 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 RKP02431.1 - 0.0029 16.7 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF87 PF01935.17 RKP02431.1 - 0.0031 17.6 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 RKP02431.1 - 0.0033 17.5 0.0 0.0094 16.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 RKP02431.1 - 0.0068 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RKP02431.1 - 0.0081 16.6 0.0 0.79 10.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKP02431.1 - 0.014 15.4 0.0 0.6 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 RKP02431.1 - 0.02 14.6 0.2 0.45 10.2 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 RKP02431.1 - 0.029 14.1 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 RKP02431.1 - 0.043 12.7 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.18 RKP02431.1 - 0.047 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AFG1_ATPase PF03969.16 RKP02431.1 - 0.095 11.6 0.0 0.5 9.2 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase TniB PF05621.11 RKP02431.1 - 0.11 11.9 0.1 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ApoB100_C PF12491.8 RKP02431.1 - 0.12 12.4 0.1 0.82 9.7 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal RsgA_GTPase PF03193.16 RKP02431.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 RKP02431.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase Peptidase_C14 PF00656.22 RKP02432.1 - 2.4e-48 165.3 0.0 3.9e-48 164.6 0.0 1.3 1 1 0 1 1 1 1 Caspase domain DUF1748 PF08520.10 RKP02435.1 - 7.6e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) NTPase_1 PF03266.15 RKP02435.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 NTPase DUF3703 PF12487.8 RKP02436.1 - 0.15 11.9 0.4 0.52 10.2 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) UDPGT PF00201.18 RKP02437.1 - 8.6e-11 41.3 0.0 1.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 RKP02437.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CcdB PF01845.17 RKP02438.1 - 3.1 8.1 6.3 1.2 9.4 0.1 3.6 3 0 0 3 3 3 0 CcdB protein DSPc PF00782.20 RKP02439.1 - 1.7e-24 86.1 0.0 2.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 RKP02439.1 - 0.016 15.8 0.0 0.51 10.9 0.0 2.9 3 0 0 3 3 3 0 Rhodanese-like domain PTPlike_phytase PF14566.6 RKP02439.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Pkinase PF00069.25 RKP02440.1 - 1.7e-35 122.7 0.0 6.9e-35 120.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02440.1 - 6.7e-13 48.5 0.0 1.5e-11 44.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKP02440.1 - 0.0004 20.4 0.0 0.0004 20.4 0.0 2.9 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP02440.1 - 0.003 16.9 0.2 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKP02440.1 - 0.15 10.8 0.7 0.28 9.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase ADK PF00406.22 RKP02441.1 - 2.1e-23 83.1 0.0 7.2e-11 42.4 0.0 2.6 2 1 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 RKP02441.1 - 1.5e-13 51.4 0.0 3e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RKP02441.1 - 2.5e-12 47.2 2.1 4.7e-11 43.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RKP02441.1 - 5.3e-07 30.2 0.0 5.7e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP02441.1 - 2.5e-05 24.7 1.9 3.4e-05 24.3 0.9 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 RKP02441.1 - 0.00013 22.4 0.0 0.0005 20.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RKP02441.1 - 0.0048 16.7 0.1 0.0099 15.6 0.1 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 RKP02441.1 - 0.0051 16.1 0.1 0.0083 15.4 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 RKP02441.1 - 0.0067 16.4 0.1 0.012 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 RKP02441.1 - 0.01 15.7 0.5 0.05 13.5 0.5 2.0 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 RKP02441.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RKP02441.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 RKP02441.1 - 0.014 15.0 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.6 RKP02441.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RKP02441.1 - 0.023 14.3 0.4 0.076 12.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RKP02441.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 RKP02441.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 RKP02441.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 RKP02441.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 RKP02441.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain dNK PF01712.19 RKP02441.1 - 0.17 11.7 0.0 0.84 9.5 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase Pkinase PF00069.25 RKP02442.1 - 2.5e-61 207.4 0.0 4.8e-41 140.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02442.1 - 4.1e-25 88.6 0.0 2.6e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 RKP02442.1 - 0.00087 18.3 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKP02442.1 - 0.0014 18.0 0.1 0.029 13.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 RKP02442.1 - 0.0021 17.4 0.1 0.0059 16.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP02442.1 - 0.014 15.4 5.6 0.21 11.5 0.3 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 RKP02442.1 - 0.04 13.5 0.1 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 RKP02442.1 - 0.092 12.4 0.0 9.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1860 PF08949.10 RKP02442.1 - 0.16 11.7 0.8 0.35 10.6 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Seadorna_VP7 PF07387.11 RKP02442.1 - 0.25 10.3 0.1 0.4 9.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cytochrom_B558a PF05038.13 RKP02443.1 - 4.5e-05 23.1 4.3 0.027 14.0 0.3 2.1 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit DUF202 PF02656.15 RKP02443.1 - 7.2 7.1 12.0 0.52 10.8 2.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ThiF PF00899.21 RKP02444.1 - 7.4e-18 64.8 0.1 9.1e-17 61.2 0.1 2.1 1 1 0 1 1 1 1 ThiF family STI1 PF17830.1 RKP02445.1 - 3.9e-07 29.9 0.4 0.00065 19.6 0.1 2.3 2 0 0 2 2 2 2 STI1 domain Nif11 PF07862.11 RKP02445.1 - 0.0067 16.7 5.4 1.5 9.2 0.1 2.9 2 1 0 2 2 2 2 Nif11 domain DUF1194 PF06707.11 RKP02445.1 - 0.035 13.3 0.1 0.035 13.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1194) AJAP1_PANP_C PF15298.6 RKP02445.1 - 5.9 7.1 9.3 16 5.6 1.8 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus GCV_H PF01597.19 RKP02446.1 - 1.4e-38 131.5 0.1 1.9e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 RKP02446.1 - 0.022 14.6 0.3 0.034 14.0 0.3 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.6 RKP02446.1 - 0.038 13.9 0.4 0.057 13.4 0.4 1.4 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF1771 PF08590.10 RKP02447.1 - 6.3e-07 29.7 0.1 6.3e-07 29.7 0.1 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 RKP02447.1 - 2.5e-06 27.3 4.1 2.5e-06 27.3 4.1 3.3 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 RKP02447.1 - 0.00017 21.4 3.1 0.00017 21.4 3.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RKP02447.1 - 0.0006 19.6 2.5 0.0006 19.6 2.5 2.9 3 1 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 RKP02447.1 - 0.016 15.9 8.8 0.028 15.1 3.0 2.5 1 1 1 2 2 2 0 Torus domain 17kDa_Anti_2 PF16998.5 RKP02447.1 - 0.02 14.8 1.4 0.074 13.0 0.9 2.3 1 1 1 2 2 2 0 17 kDa outer membrane surface antigen zf-CCCH_3 PF15663.5 RKP02447.1 - 0.03 14.5 6.8 0.076 13.2 0.3 2.3 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 RKP02447.1 - 0.069 13.6 12.4 1 9.9 2.3 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Sedlin_N PF04628.13 RKP02449.1 - 5e-35 120.5 0.0 5.7e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 RKP02449.1 - 0.0014 18.6 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family G-patch PF01585.23 RKP02450.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 G-patch domain FAP206 PF12018.8 RKP02452.1 - 1.7e-44 152.4 0.0 5.6e-44 150.7 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function Herpes_UL24 PF01646.16 RKP02452.1 - 0.0095 15.9 0.5 0.07 13.1 0.4 2.2 2 0 0 2 2 2 1 Herpes virus proteins UL24 and UL76 PilJ PF13675.6 RKP02452.1 - 0.17 12.0 1.6 3.7 7.6 0.3 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MFS_1 PF07690.16 RKP02453.1 - 2.1e-40 138.8 52.7 2.1e-40 138.8 52.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RKP02453.1 - 4.7e-05 22.0 8.5 4.7e-05 22.0 8.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ost4 PF10215.9 RKP02453.1 - 3.1 7.7 5.5 14 5.6 1.3 3.2 2 0 0 2 2 2 0 Oligosaccaryltransferase PX PF00787.24 RKP02455.1 - 1.9e-20 72.9 0.1 4.2e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 RKP02455.1 - 2.6e-11 43.5 6.5 2.4e-05 24.0 0.7 2.2 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.11 RKP02455.1 - 0.06 12.7 1.0 0.17 11.3 1.0 1.7 1 0 0 1 1 1 0 FAM92 protein ABC_tran_CTD PF16326.5 RKP02455.1 - 6.2 7.2 7.0 2 8.7 0.7 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain Pkinase PF00069.25 RKP02456.1 - 1.7e-19 70.2 0.0 1.8e-12 47.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02456.1 - 1.2e-07 31.3 0.0 2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP02456.1 - 0.00084 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKP02456.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1180 PF06679.12 RKP02457.1 - 0.0077 16.7 1.7 0.0077 16.7 1.7 6.9 3 2 2 5 5 5 1 Protein of unknown function (DUF1180) PMP1_2 PF08114.11 RKP02457.1 - 0.071 12.9 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Pkinase PF00069.25 RKP02459.1 - 3.2e-72 243.1 0.0 3.7e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02459.1 - 1e-54 185.6 0.0 1.3e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02459.1 - 1.7e-06 27.6 0.0 4.2e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKP02459.1 - 0.006 15.4 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKP02459.1 - 0.0066 16.4 0.1 0.033 14.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RKP02459.1 - 0.044 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Fz PF01392.22 RKP02460.1 - 0.04 14.5 0.2 0.12 13.0 0.0 1.8 2 0 0 2 2 2 0 Fz domain MFS_1 PF07690.16 RKP02461.1 - 2.8e-12 46.2 33.9 2.8e-12 46.2 33.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 RKP02461.1 - 1.2e-08 34.8 17.7 7.1e-08 32.3 17.7 2.1 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 TPH PF13868.6 RKP02463.1 - 2.8e-21 75.4 119.7 2.8e-21 75.4 119.7 2.2 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain SET PF00856.28 RKP02465.1 - 5.1e-16 59.5 0.0 6.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 SET domain CIMR PF00878.18 RKP02465.1 - 0.037 14.1 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat TPR_1 PF00515.28 RKP02466.1 - 0.00013 21.7 0.6 3.7 7.5 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKP02466.1 - 0.00041 20.9 1.2 0.00041 20.9 1.2 12.9 12 2 3 15 15 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKP02466.1 - 0.0012 19.4 1.2 0.0047 17.4 0.6 12.5 10 3 3 13 13 13 4 Tetratricopeptide repeat TPR_2 PF07719.17 RKP02466.1 - 0.042 14.0 34.2 0.24 11.6 0.1 8.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.8 RKP02467.1 - 0.062 13.3 2.6 0.16 12.0 2.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Med21 PF11221.8 RKP02467.1 - 0.57 10.4 4.3 1.2 9.4 0.3 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AAA PF00004.29 RKP02468.1 - 6.4e-88 291.9 0.0 1e-47 161.9 0.0 2.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKP02468.1 - 3.2e-20 71.6 4.3 7.4e-12 44.9 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 RKP02468.1 - 4.1e-13 50.1 8.6 0.00047 20.6 0.3 5.5 3 2 0 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 RKP02468.1 - 6.8e-13 48.7 0.0 3.2e-05 23.7 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RKP02468.1 - 1.7e-10 41.0 0.2 0.0012 18.8 0.0 4.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP02468.1 - 6.9e-10 39.3 2.6 0.01 16.1 0.0 5.0 3 2 2 5 5 5 2 AAA domain AAA_33 PF13671.6 RKP02468.1 - 9.2e-10 38.8 0.0 0.0017 18.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 RKP02468.1 - 1.5e-08 35.3 0.0 0.017 15.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.14 RKP02468.1 - 2.4e-08 34.3 0.0 7.4e-05 22.9 0.0 3.1 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 RKP02468.1 - 3.1e-08 34.0 0.0 0.0051 17.2 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 RKP02468.1 - 1e-07 32.1 0.0 0.0023 17.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 RKP02468.1 - 3.2e-07 30.3 0.1 0.031 14.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 RKP02468.1 - 3.4e-07 30.4 0.0 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 RKP02468.1 - 6.7e-07 28.8 0.1 0.015 14.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 RKP02468.1 - 8.6e-07 28.5 1.1 0.017 14.5 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 RKP02468.1 - 8.8e-07 29.3 0.1 0.075 13.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 RKP02468.1 - 1.7e-06 28.6 0.0 0.048 14.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 RKP02468.1 - 2.3e-06 27.6 0.0 0.057 13.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 RKP02468.1 - 3.3e-06 26.6 0.0 0.035 13.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain NACHT PF05729.12 RKP02468.1 - 4.3e-06 26.7 0.0 0.13 12.2 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_25 PF13481.6 RKP02468.1 - 7.1e-06 25.7 1.3 0.14 11.7 0.1 4.0 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 RKP02468.1 - 8.9e-06 25.5 0.0 0.069 12.9 0.0 3.2 4 0 0 4 4 3 2 Sigma-54 interaction domain AAA_17 PF13207.6 RKP02468.1 - 1.4e-05 25.5 0.2 0.29 11.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 RKP02468.1 - 1.7e-05 24.7 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 RKP02468.1 - 0.00011 22.3 0.9 0.2 11.6 0.0 4.0 4 1 1 5 5 5 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 RKP02468.1 - 0.00014 21.2 0.0 0.29 10.3 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain DUF815 PF05673.13 RKP02468.1 - 0.00028 20.1 0.0 0.75 8.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 RKP02468.1 - 0.00034 20.2 0.0 0.26 10.8 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_11 PF13086.6 RKP02468.1 - 0.00056 19.8 0.0 0.83 9.4 0.1 2.8 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 RKP02468.1 - 0.00072 19.7 0.1 1.8 8.7 0.0 3.3 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 RKP02468.1 - 0.0012 18.6 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 RKP02468.1 - 0.0014 18.8 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase ATPase PF06745.13 RKP02468.1 - 0.0015 17.9 0.3 0.64 9.3 0.0 2.7 3 0 0 3 3 3 1 KaiC Cytidylate_kin2 PF13189.6 RKP02468.1 - 0.0019 18.4 0.1 2 8.5 0.0 2.5 3 0 0 3 3 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.17 RKP02468.1 - 0.0031 16.7 0.0 0.92 8.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PhoH PF02562.16 RKP02468.1 - 0.0038 16.7 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 RKP02468.1 - 0.0088 16.4 0.2 7.2 6.9 0.1 3.2 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 RKP02468.1 - 0.0088 14.9 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_3 PF07726.11 RKP02468.1 - 0.01 15.7 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 RKP02468.1 - 0.014 15.5 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Torsin AFG1_ATPase PF03969.16 RKP02468.1 - 0.031 13.2 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.9 RKP02468.1 - 0.039 13.2 0.6 1.9 7.6 0.0 2.8 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 RKP02468.1 - 0.057 13.2 3.0 1.4 8.6 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase UPF0167 PF03691.14 RKP02468.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) AAA_29 PF13555.6 RKP02468.1 - 0.11 12.2 0.0 9.2 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RKP02468.1 - 0.13 12.0 1.4 11 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 RKP02468.1 - 0.22 11.3 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 RKP02468.1 - 0.37 11.3 1.3 45 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 RKP02470.1 - 5.8e-59 199.6 0.0 6.7e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02470.1 - 1.3e-31 109.9 0.0 1.5e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02470.1 - 1.9e-05 24.1 0.0 3.2e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP02470.1 - 0.00012 21.0 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 RKP02470.1 - 0.001 18.7 0.1 0.7 9.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 RKP02470.1 - 0.0014 17.7 0.1 0.0018 17.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Phlebovirus_G1 PF07243.11 RKP02470.1 - 0.0044 15.5 0.1 0.0065 14.9 0.1 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G1 Seadorna_VP7 PF07387.11 RKP02470.1 - 0.0078 15.3 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Aldedh PF00171.22 RKP02471.1 - 3.6e-165 550.0 0.0 4e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 RKP02471.1 - 0.0014 18.1 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Gpi16 PF04113.14 RKP02472.1 - 8.9e-145 483.3 0.0 2.4e-143 478.5 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Ribonuc_L-PSP PF01042.21 RKP02473.1 - 1e-27 96.6 0.0 1.4e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP CTP_transf_like PF01467.26 RKP02474.1 - 3.9e-05 23.9 0.1 0.00015 22.0 0.1 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like RasGAP PF00616.19 RKP02475.1 - 7.8e-21 74.7 0.0 3e-13 50.0 0.0 3.0 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase TPX2 PF06886.11 RKP02477.1 - 4.3e-07 30.1 6.6 4.3e-07 30.1 6.6 3.5 4 0 0 4 4 4 1 Targeting protein for Xklp2 (TPX2) TPX2_importin PF12214.8 RKP02477.1 - 1.3e-05 25.4 0.9 1.3e-05 25.4 0.9 6.4 4 2 2 6 6 6 3 Cell cycle regulated microtubule associated protein RabGAP-TBC PF00566.18 RKP02478.1 - 1.7e-35 122.6 0.0 2.4e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DJ-1_PfpI PF01965.24 RKP02479.1 - 2.4e-15 56.7 0.0 9.7e-13 48.2 0.0 2.9 1 1 0 1 1 1 1 DJ-1/PfpI family zf-RING_2 PF13639.6 RKP02480.1 - 9.4e-05 22.7 4.6 9.4e-05 22.7 4.6 2.3 2 0 0 2 2 2 1 Ring finger domain Apolipoprotein PF01442.18 RKP02481.1 - 3.9e-05 23.6 146.2 0.00013 22.0 23.6 7.2 1 1 5 7 7 7 3 Apolipoprotein A1/A4/E domain HSP20 PF00011.21 RKP02481.1 - 0.00012 22.2 0.1 0.0003 20.9 0.1 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF883 PF05957.13 RKP02481.1 - 0.00012 22.6 210.9 0.063 13.9 4.3 16.1 1 1 14 16 16 16 9 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 RKP02481.1 - 0.12 12.9 160.2 1.2 9.8 0.9 16.4 3 3 7 10 10 10 0 YtxH-like protein Thymidylat_synt PF00303.19 RKP02482.1 - 1.5e-100 335.7 0.0 1.9e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase Arfaptin PF06456.13 RKP02483.1 - 1e-19 71.0 6.2 2e-19 70.1 6.2 1.4 1 1 0 1 1 1 1 Arfaptin-like domain MMR_HSR1 PF01926.23 RKP02484.1 - 9.2e-15 54.7 0.5 3e-14 53.0 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP02484.1 - 8e-06 25.5 0.1 1.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RKP02484.1 - 6.1e-05 23.0 0.0 0.00065 19.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 RKP02484.1 - 0.012 14.9 0.1 0.038 13.3 0.1 1.7 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 RKP02484.1 - 0.067 12.7 0.2 0.29 10.7 0.1 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 RKP02484.1 - 0.09 13.3 0.5 0.17 12.5 0.5 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 RKP02484.1 - 0.14 12.2 1.1 5 7.1 0.1 2.5 2 1 0 3 3 3 0 Dynamin family IIGP PF05049.13 RKP02484.1 - 0.22 10.5 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Exo84_C PF16528.5 RKP02485.1 - 3.8e-22 79.1 0.2 5e-15 55.9 0.0 3.4 3 0 0 3 3 3 3 Exocyst component 84 C-terminal Vps51 PF08700.11 RKP02485.1 - 1.9e-13 50.3 0.0 6.1e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 RKP02485.1 - 0.012 15.7 0.2 0.041 14.0 0.2 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ENTH PF01417.20 RKP02486.1 - 3.7e-46 156.2 0.1 7.8e-46 155.2 0.1 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 RKP02486.1 - 0.00043 20.0 10.2 0.17 11.9 2.3 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 RKP02486.1 - 0.0081 15.2 0.0 0.0081 15.2 0.0 2.2 2 1 0 2 2 2 1 ANTH domain TFIIA PF03153.13 RKP02486.1 - 0.68 9.9 31.0 1.1 9.2 31.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNRNP27 PF08648.12 RKP02487.1 - 1.4e-24 85.9 0.1 1.6e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins AMP-binding PF00501.28 RKP02488.1 - 4.3e-85 285.9 0.0 5.9e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKP02488.1 - 0.00067 20.6 0.0 0.0025 18.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 RKP02489.1 - 9.8e-74 248.0 0.0 1.1e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02489.1 - 1.2e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02489.1 - 0.00079 18.8 1.9 0.72 9.1 0.0 3.3 3 1 1 4 4 4 2 Kinase-like Pkinase_fungal PF17667.1 RKP02489.1 - 0.057 12.2 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase MRP-L28 PF09812.9 RKP02490.1 - 9.8e-06 25.8 0.1 1.6e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RA PF00788.23 RKP02491.1 - 1.8e-09 38.1 0.0 3.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 RKP02491.1 - 6.5e-07 28.9 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP02491.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain FERM_N PF09379.10 RKP02491.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FERM N-terminal domain Par3_HAL_N_term PF12053.8 RKP02491.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Thioredoxin PF00085.20 RKP02493.1 - 5e-28 97.1 0.4 5.3e-28 97.0 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 RKP02493.1 - 0.00027 21.2 0.0 0.00048 20.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 RKP02493.1 - 0.00035 20.5 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 RKP02493.1 - 0.00088 18.3 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 RKP02493.1 - 0.0029 18.0 0.1 0.013 15.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 RKP02493.1 - 0.0065 15.9 0.0 0.0071 15.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 RKP02493.1 - 0.013 15.2 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Redoxin APG5 PF04106.12 RKP02494.1 - 5.5e-30 104.6 0.0 1.2e-28 100.3 0.0 2.6 1 1 0 1 1 1 1 Autophagy protein Apg5 HHH_3 PF12836.7 RKP02494.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif CBFD_NFYB_HMF PF00808.23 RKP02495.1 - 2.4e-11 43.7 0.2 3e-11 43.5 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_2 PF12796.7 RKP02496.1 - 1.7e-09 38.1 1.6 0.0046 17.5 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) VPS9 PF02204.18 RKP02496.1 - 2.4e-08 34.1 0.0 2.8e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.6 RKP02496.1 - 9.6e-08 32.4 4.6 0.15 12.6 0.1 5.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP02496.1 - 3.2e-05 24.0 3.8 49 5.0 0.0 7.4 7 0 0 7 7 7 0 Ankyrin repeat TPR_19 PF14559.6 RKP02497.1 - 9.5e-26 90.1 37.4 0.00046 20.6 0.3 12.0 6 4 4 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 RKP02497.1 - 2.3e-15 55.4 36.7 0.023 14.8 1.1 13.0 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 RKP02497.1 - 5.3e-11 41.8 22.7 0.047 13.9 0.0 11.0 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKP02497.1 - 7.1e-11 42.0 55.2 0.001 19.7 0.9 12.4 9 4 5 14 14 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 RKP02497.1 - 3.5e-10 40.0 40.9 0.00072 19.8 3.0 10.6 8 4 2 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKP02497.1 - 3.2e-09 37.3 37.3 0.00012 22.6 0.6 8.0 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKP02497.1 - 6.9e-08 32.1 11.4 0.021 14.5 0.0 7.2 9 1 0 9 9 8 3 TPR repeat TPR_17 PF13431.6 RKP02497.1 - 3.8e-07 30.0 28.3 0.71 10.4 0.0 12.0 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP02497.1 - 3.3e-05 23.9 36.2 0.0093 16.1 0.4 8.9 5 3 3 8 8 8 2 Tetratricopeptide repeat Coatomer_E PF04733.14 RKP02497.1 - 0.00014 21.3 3.6 0.029 13.8 1.0 3.6 4 0 0 4 4 4 1 Coatomer epsilon subunit TPR_1 PF00515.28 RKP02497.1 - 0.00056 19.6 39.0 0.13 12.1 0.2 10.0 12 1 0 12 12 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP02497.1 - 0.00086 19.5 20.1 0.66 10.2 0.1 6.9 4 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 RKP02497.1 - 0.0062 16.6 0.3 0.082 13.0 0.1 2.9 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 RKP02497.1 - 0.06 13.4 3.2 1.9 8.6 0.0 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 RKP02497.1 - 0.064 13.9 33.3 2.2 9.1 0.2 10.7 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKP02497.1 - 0.25 11.5 21.2 4 7.7 0.1 8.2 11 0 0 11 11 10 0 Tetratricopeptide repeat HA2 PF04408.23 RKP02498.1 - 3.3e-19 69.2 0.0 7.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RKP02498.1 - 4.8e-15 55.9 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKP02498.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RKP02498.1 - 0.00043 20.6 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKP02498.1 - 0.00069 20.0 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 RKP02498.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 RKP02498.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 RKP02498.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 RKP02498.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKP02498.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 RKP02498.1 - 0.063 12.6 0.1 0.17 11.1 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 RKP02498.1 - 0.067 13.6 0.2 0.25 11.7 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 RKP02498.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 RKP02498.1 - 0.14 11.8 0.1 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase dCMP_cyt_deam_1 PF00383.23 RKP02501.1 - 1.1e-18 67.0 0.0 1.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RKP02501.1 - 3.4e-15 56.0 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 RKP02501.1 - 5.7e-05 23.2 2.7 0.0009 19.3 2.7 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC4_like PF18774.1 RKP02501.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 RKP02501.1 - 0.055 13.6 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 PDZ_1 PF12812.7 RKP02502.1 - 1.1e-27 95.9 0.0 4e-22 78.0 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 RKP02502.1 - 5.9e-19 69.4 2.1 1.3e-17 65.1 0.1 2.8 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 RKP02502.1 - 9.1e-11 41.9 0.0 0.0098 16.2 0.0 4.5 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 RKP02502.1 - 2.1e-09 37.1 0.1 5.1e-05 23.0 0.1 3.8 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 RKP02502.1 - 2.3e-06 27.9 0.0 0.036 14.4 0.0 3.2 3 0 0 3 3 3 2 PDZ domain Peptidase_S46 PF10459.9 RKP02502.1 - 0.00086 18.1 0.3 0.0065 15.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase S46 Trypsin PF00089.26 RKP02502.1 - 0.0032 17.3 0.0 0.009 15.8 0.0 1.7 2 0 0 2 2 2 1 Trypsin DUF31 PF01732.16 RKP02502.1 - 0.027 14.0 0.2 0.042 13.4 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) CTD_bind PF04818.13 RKP02503.1 - 0.1 13.4 0.0 0.32 11.8 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Fructosamin_kin PF03881.14 RKP02504.1 - 0.00044 19.5 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase YdjM PF04307.14 RKP02504.1 - 0.047 13.0 0.2 0.052 12.9 0.2 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Las1 PF04031.13 RKP02506.1 - 1.1e-42 145.8 0.4 1.1e-42 145.8 0.4 2.7 3 0 0 3 3 3 2 Las1-like PIG-U PF06728.13 RKP02507.1 - 1.1e-76 258.4 17.6 1.2e-76 258.2 17.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 RKP02507.1 - 0.14 11.9 9.0 0.65 9.7 9.0 1.9 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain DUF4378 PF14309.6 RKP02508.1 - 0.18 12.2 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Tmemb_cc2 PF10267.9 RKP02508.1 - 1.1 8.3 2.9 2.2 7.3 0.3 2.6 3 0 0 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein DUF5082 PF16888.5 RKP02508.1 - 5.9 7.2 4.7 46 4.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Mito_carr PF00153.27 RKP02509.1 - 1.6e-54 181.8 5.9 8.3e-18 64.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 RKP02509.1 - 0.0024 17.9 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 2 PrcB C-terminal Pox_A14 PF05767.12 RKP02509.1 - 0.1 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MtrF PF09472.10 RKP02509.1 - 1.1 8.7 0.0 1.1 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) UBX PF00789.20 RKP02510.1 - 1.6e-13 50.6 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 RKP02510.1 - 2.7e-06 27.1 0.1 5.5e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain Maf PF02545.14 RKP02511.1 - 1.5e-25 90.0 0.0 1.7e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein TMEM223 PF14640.6 RKP02512.1 - 4e-14 53.1 0.0 5.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 TMEM70 PF06979.12 RKP02512.1 - 0.00046 20.6 0.1 0.0013 19.1 0.0 1.8 1 1 1 2 2 2 1 Assembly, mitochondrial proton-transport ATP synth complex Rad21_Rec8_N PF04825.13 RKP02513.1 - 2.5e-38 130.6 0.0 4.1e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RKP02513.1 - 8.4e-05 21.8 0.2 0.0002 20.6 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Glyco_transf_41 PF13844.6 RKP02514.1 - 2.6e-54 184.4 0.0 3.5e-50 170.8 0.0 3.6 4 0 0 4 4 4 3 Glycosyl transferase family 41 NMT_C PF02799.15 RKP02515.1 - 1.5e-68 230.4 0.0 2.1e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 RKP02515.1 - 2.5e-68 228.9 0.0 3.6e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Porin_3 PF01459.22 RKP02516.1 - 7.3e-43 147.0 0.0 1e-30 107.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic porin eIF2A PF08662.11 RKP02517.1 - 4.6e-37 127.8 5.0 9.4e-35 120.3 1.1 4.2 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 RKP02517.1 - 2.6e-05 24.0 0.0 8.5e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 RKP02517.1 - 0.003 15.7 0.7 0.49 8.3 0.0 2.8 1 1 1 2 2 2 2 IKI3 family WD40 PF00400.32 RKP02517.1 - 0.009 16.9 9.9 2.7 9.0 0.1 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat BTAD PF03704.17 RKP02518.1 - 1.7 9.1 7.3 0.11 12.9 1.5 1.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain PNK3P PF08645.11 RKP02519.1 - 1.4e-45 154.9 0.0 1.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 RKP02519.1 - 6e-14 52.4 0.0 1.2e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydrolase_6 PF13344.6 RKP02519.1 - 0.0024 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase AAA_30 PF13604.6 RKP02519.1 - 0.0078 15.9 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKP02519.1 - 0.0095 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI HAD PF12710.7 RKP02519.1 - 0.039 14.4 0.9 6.3 7.2 0.3 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase AAA_22 PF13401.6 RKP02519.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKP02519.1 - 0.053 12.9 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 RKP02519.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Hydrolase PF00702.26 RKP02519.1 - 0.14 12.5 0.2 3.6 7.8 0.2 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase T2SSE PF00437.20 RKP02519.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 RKP02519.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.10 RKP02519.1 - 0.29 10.5 0.0 0.43 10.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MBOAT PF03062.19 RKP02520.1 - 4.9e-34 118.2 22.1 4.9e-34 118.2 22.1 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DHHC PF01529.20 RKP02521.1 - 5.8e-34 117.1 1.0 5.8e-34 117.1 1.0 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Neurensin PF14927.6 RKP02521.1 - 0.25 11.1 0.9 0.68 9.6 0.0 2.2 2 1 0 2 2 2 0 Neurensin DZR PF12773.7 RKP02521.1 - 1.1 9.4 6.6 1.9 8.6 6.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Imm5 PF14423.6 RKP02521.1 - 2.1 8.5 3.8 4 7.6 3.8 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 NCE101 PF11654.8 RKP02521.1 - 8.1 6.2 5.3 1.7 8.4 0.2 2.3 2 0 0 2 2 2 0 Non-classical export protein 1 ERCC3_RAD25_C PF16203.5 RKP02522.1 - 1.8e-100 335.2 0.0 3.1e-100 334.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 RKP02522.1 - 2.3e-32 111.8 0.2 5.2e-32 110.7 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP02522.1 - 4.2e-16 59.4 0.0 6.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKP02522.1 - 3.6e-11 43.4 0.2 2e-10 41.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 RKP02522.1 - 4e-08 32.4 0.0 5.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 RKP02522.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5309 PF17236.2 RKP02522.1 - 0.12 11.7 0.1 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5309) Sec3_C PF09763.9 RKP02523.1 - 1.8e-109 367.1 0.0 2.3e-109 366.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.12 RKP02523.1 - 1e-05 24.5 0.4 2.1e-05 23.5 0.4 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3-PIP2_bind PF15277.6 RKP02523.1 - 1.5e-05 25.0 0.0 3.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH SKA2 PF16740.5 RKP02523.1 - 0.45 10.3 4.2 25 4.7 0.0 3.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Arm PF00514.23 RKP02524.1 - 2.1e-29 100.6 21.4 1.1e-05 25.3 1.0 8.9 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RKP02524.1 - 1.4e-23 81.0 10.3 0.002 18.2 0.0 7.8 7 0 0 7 7 7 6 HEAT repeat HEAT_2 PF13646.6 RKP02524.1 - 2e-18 66.6 20.7 3.7e-05 24.0 0.9 5.8 3 1 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 RKP02524.1 - 2.4e-16 59.8 24.3 2.8e-05 24.5 1.0 6.6 4 1 2 6 6 6 5 HEAT-like repeat Cnd1 PF12717.7 RKP02524.1 - 2.8e-14 53.5 3.2 6e-06 26.4 0.1 4.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKP02524.1 - 1.1e-08 34.1 7.6 0.00012 20.8 1.2 3.6 2 1 0 3 3 3 3 Adaptin N terminal region RICTOR_V PF14668.6 RKP02524.1 - 4.7e-06 26.7 1.9 0.091 13.0 0.0 4.3 5 0 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 CLASP_N PF12348.8 RKP02524.1 - 0.00046 19.8 2.1 0.0093 15.6 0.2 3.0 1 1 2 3 3 3 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 RKP02524.1 - 0.0074 16.9 0.5 1.3 9.6 0.0 4.2 3 1 3 6 6 6 1 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.9 RKP02524.1 - 0.009 14.6 7.1 0.47 8.9 0.9 3.3 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit Mo25 PF08569.11 RKP02524.1 - 0.05 13.0 0.1 1 8.7 0.1 2.3 1 1 1 2 2 2 0 Mo25-like U3snoRNP10 PF12397.8 RKP02524.1 - 0.064 13.6 4.1 15 6.0 0.1 3.9 3 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 10 HEAT_PBS PF03130.16 RKP02524.1 - 0.065 13.9 0.2 0.065 13.9 0.2 7.5 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat API5 PF05918.11 RKP02524.1 - 0.067 12.0 0.8 0.26 10.1 0.5 1.9 1 1 1 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DUF3731 PF12531.8 RKP02524.1 - 0.096 12.5 6.5 2.7 7.7 0.2 3.3 3 1 0 3 3 3 0 DNA-K related protein TAF6_C PF07571.13 RKP02524.1 - 0.25 11.7 2.3 11 6.4 0.0 4.1 3 1 2 5 5 5 0 TAF6 C-terminal HEAT repeat domain HSP20 PF00011.21 RKP02525.1 - 0.00034 20.7 0.0 0.0014 18.7 0.0 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RKP02525.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Ran_BP1 PF00638.18 RKP02526.1 - 2.5e-12 47.1 0.0 4.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain PI3_PI4_kinase PF00454.27 RKP02527.1 - 1.3e-45 156.2 0.0 1.6e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 RKP02527.1 - 1.3e-14 53.7 0.0 2.5e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 FATC domain RIIa PF02197.17 RKP02528.1 - 0.0013 18.3 0.2 0.0023 17.6 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Caleosin PF05042.13 RKP02528.1 - 0.053 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Caleosin related protein TMEM234 PF10639.9 RKP02529.1 - 4.6e-35 120.1 1.2 5.2e-35 120.0 1.2 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 RKP02529.1 - 6.8e-08 32.8 5.4 1.1e-05 25.6 5.0 2.0 1 1 1 2 2 2 2 EamA-like transporter family CH PF00307.31 RKP02530.1 - 0.00092 19.4 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain HC2 PF07382.11 RKP02530.1 - 0.0018 18.4 81.4 0.0018 18.4 81.4 6.1 3 1 3 6 6 6 3 Histone H1-like nucleoprotein HC2 NUDIX PF00293.28 RKP02531.1 - 1.8e-12 47.4 0.0 2.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 RKP02531.1 - 0.00085 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) LCM PF04072.14 RKP02532.1 - 2.8e-29 102.4 0.0 1.8e-28 99.8 0.0 2.0 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase ATP-synt_ab_Xtn PF16886.5 RKP02532.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension PH PF00169.29 RKP02533.1 - 2.8e-38 130.6 3.9 2.7e-21 76.0 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 RKP02533.1 - 5.5e-08 33.2 22.5 3.2e-05 24.3 6.5 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 RKP02533.1 - 1.2e-07 32.1 5.0 0.0011 19.4 1.4 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 RKP02533.1 - 1.5e-05 25.1 0.7 6.5e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 RKP02533.1 - 8.4e-05 22.8 2.4 0.0011 19.2 0.7 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Myosin_TH1 PF06017.13 RKP02533.1 - 0.00039 20.1 0.1 0.037 13.7 0.0 2.1 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding PH_6 PF15406.6 RKP02533.1 - 0.0042 17.4 0.1 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 RKP02533.1 - 0.0044 16.8 0.3 1 9.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 RKP02533.1 - 0.038 13.8 0.8 0.081 12.8 0.1 1.8 2 0 0 2 2 2 0 PH domain PH_2 PF08458.10 RKP02533.1 - 0.092 13.1 0.9 0.75 10.2 0.0 2.1 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_15 PF17339.2 RKP02533.1 - 0.17 11.8 3.6 1.8 8.5 0.4 2.2 2 0 0 2 2 2 0 PH domain PH_4 PF15404.6 RKP02533.1 - 0.37 10.5 2.7 9 6.0 0.1 3.3 3 1 1 4 4 4 0 Pleckstrin homology domain DNA_pol3_delta2 PF13177.6 RKP02534.1 - 2.6e-13 50.1 0.0 4.5e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 RKP02534.1 - 1.1e-06 29.1 0.0 2.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP02534.1 - 0.00054 20.4 0.6 0.0017 18.8 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 RKP02534.1 - 0.0014 19.0 0.0 0.0045 17.4 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 RKP02534.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 RKP02534.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phyto-Amp PF15438.6 RKP02534.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma AAA_assoc_2 PF16193.5 RKP02534.1 - 0.019 15.3 0.2 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA C-terminal domain AAA_24 PF13479.6 RKP02534.1 - 0.025 14.3 0.2 0.12 12.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RKP02534.1 - 0.043 13.2 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RKP02534.1 - 0.048 13.9 0.4 0.33 11.2 0.3 2.3 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 RKP02534.1 - 0.12 12.1 0.0 3.2 7.5 0.0 2.7 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Asp PF00026.23 RKP02535.1 - 3.7e-54 184.3 7.9 7.8e-54 183.2 7.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKP02535.1 - 9.8e-12 45.5 4.9 7.4e-06 26.3 0.4 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RKP02535.1 - 7e-07 29.8 1.5 0.0011 19.5 0.3 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RKP02535.1 - 0.00044 20.8 3.5 0.039 14.5 0.0 2.8 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 RKP02535.1 - 0.01 15.6 0.1 0.05 13.4 0.1 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 RKP02536.1 - 2.7e-45 155.1 0.3 7.4e-42 143.9 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKP02536.1 - 2.2e-11 44.3 2.5 2.1e-05 24.8 0.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 RKP02536.1 - 0.0014 19.1 0.8 0.051 14.1 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 RKP02536.1 - 0.0038 17.8 6.0 0.26 11.9 0.1 3.7 3 1 0 3 3 3 2 Aspartyl protease WD40 PF00400.32 RKP02537.1 - 3.1e-13 50.0 6.3 0.00032 21.4 0.0 6.3 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02537.1 - 8.4e-07 29.2 0.0 0.33 11.3 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RKP02537.1 - 0.015 15.8 0.1 11 6.6 0.1 3.6 3 0 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.6 RKP02537.1 - 0.017 14.7 0.0 1.3 8.6 0.0 3.1 3 1 0 4 4 4 0 PQQ-like domain DUF1989 PF09347.10 RKP02537.1 - 0.052 13.2 1.8 2.9 7.5 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1989) PALB2_WD40 PF16756.5 RKP02537.1 - 0.099 11.5 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain FMO-like PF00743.19 RKP02538.1 - 3.2e-42 144.7 0.0 9.9e-24 83.6 0.0 3.8 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 RKP02538.1 - 4.5e-19 68.8 0.0 5.8e-10 38.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 RKP02538.1 - 3.4e-14 52.8 0.0 8.3e-12 44.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RKP02538.1 - 1.4e-08 34.3 0.3 3.5e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 RKP02538.1 - 9.7e-06 25.7 2.2 2.6e-05 24.4 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RKP02538.1 - 1.4e-05 25.6 0.1 0.09 13.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RKP02538.1 - 7.9e-05 22.2 1.4 0.0003 20.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 RKP02538.1 - 8.8e-05 22.2 2.9 0.0042 16.7 0.0 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 RKP02538.1 - 0.00027 20.3 0.1 0.031 13.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 RKP02538.1 - 0.00054 18.8 0.7 0.0029 16.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 RKP02538.1 - 0.00059 19.0 0.0 0.00059 19.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 RKP02538.1 - 0.0018 17.6 0.0 0.0051 16.2 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 RKP02538.1 - 0.0021 17.4 0.4 0.097 12.0 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 RKP02538.1 - 0.0034 17.4 1.0 1.5 8.8 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 RKP02538.1 - 0.011 15.0 0.4 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 RKP02538.1 - 0.043 12.9 0.6 0.043 12.9 0.6 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RKP02538.1 - 0.072 12.1 0.0 0.79 8.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GlnE PF03710.15 RKP02538.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase NAD_binding_7 PF13241.6 RKP02538.1 - 0.19 12.2 0.2 7.4 7.1 0.2 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Isy1 PF06246.12 RKP02539.1 - 4.3e-66 223.1 3.8 6e-66 222.6 3.8 1.2 1 0 0 1 1 1 1 Isy1-like splicing family Anoctamin PF04547.12 RKP02540.1 - 1.8e-83 280.9 0.4 2e-83 280.7 0.4 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel UCH PF00443.29 RKP02541.1 - 6.6e-48 163.4 0.0 8.2e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP02541.1 - 2.8e-15 56.7 0.3 5.5e-15 55.8 0.3 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RKP02541.1 - 3.9e-09 36.7 8.4 3.9e-09 36.7 8.4 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Mut7-C PF01927.16 RKP02541.1 - 0.0054 16.8 0.3 0.0054 16.8 0.3 2.4 3 0 0 3 3 3 1 Mut7-C RNAse domain zf-UBP_var PF17807.1 RKP02541.1 - 0.74 9.6 4.4 0.52 10.1 1.8 2.2 2 0 0 2 2 2 0 Variant UBP zinc finger Herpes_gE PF02480.16 RKP02542.1 - 0.011 14.5 0.0 0.011 14.5 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E PMP1_2 PF08114.11 RKP02542.1 - 0.21 11.4 3.2 0.44 10.3 3.2 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Macoilin PF09726.9 RKP02542.1 - 1.2 7.6 10.8 1.5 7.3 10.8 1.1 1 0 0 1 1 1 0 Macoilin family TUTF7_u4 PF16631.5 RKP02542.1 - 6.2 7.5 8.4 1 10.1 4.3 1.8 2 0 0 2 2 2 0 Unstructured region 4 on terminal uridylyltransferase 7 FAM72 PF14976.6 RKP02543.1 - 5.2e-49 166.1 4.1 6.2e-49 165.9 4.1 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 RKP02543.1 - 0.086 13.1 7.4 0.13 12.5 7.4 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.25 RKP02544.1 - 1.6e-29 103.1 0.0 3.8e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain WW PF00397.26 RKP02544.1 - 1.1e-10 41.4 1.4 0.00028 20.9 0.3 2.5 2 0 0 2 2 2 2 WW domain p25-alpha PF05517.12 RKP02545.1 - 2.4e-51 173.9 1.4 5.6e-40 137.0 0.0 2.3 2 0 0 2 2 2 2 p25-alpha GST_N PF02798.20 RKP02546.1 - 1.5e-17 63.7 0.0 3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 RKP02546.1 - 1e-11 44.9 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RKP02546.1 - 3.2e-11 43.5 0.0 5.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 RKP02546.1 - 1.4e-10 41.2 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RKP02546.1 - 3e-08 33.9 0.0 6.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RKP02546.1 - 3.7e-08 33.3 0.0 6.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1356 PF07092.12 RKP02547.1 - 0.00027 20.3 0.0 0.0004 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DUF3598 PF12204.8 RKP02548.1 - 0.00048 19.7 0.4 0.00078 19.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3598) UPF0126 PF03458.13 RKP02548.1 - 0.17 11.8 2.1 0.77 9.7 0.1 2.3 2 0 0 2 2 2 0 UPF0126 domain CBM_21 PF03370.13 RKP02549.1 - 1.8e-13 50.6 0.0 2.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 RKP02549.1 - 0.00071 20.1 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) SH3_1 PF00018.28 RKP02550.1 - 2.3e-06 27.1 0.0 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RKP02550.1 - 0.0042 16.9 0.1 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 RKP02550.1 - 0.12 12.1 0.1 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain SUIM_assoc PF16619.5 RKP02550.1 - 0.22 11.6 4.2 0.51 10.4 4.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_M28 PF04389.17 RKP02551.1 - 3.3e-36 124.8 0.0 4.8e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 RKP02551.1 - 1.2e-05 25.3 0.1 2.4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 RKP02551.1 - 0.00019 21.2 0.0 0.00042 20.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Ras PF00071.22 RKP02552.1 - 1.7e-50 170.8 0.0 1.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP02552.1 - 3.5e-18 65.9 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP02552.1 - 4.7e-11 42.4 0.0 5.1e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKP02552.1 - 1.3e-08 34.6 0.2 5.1e-08 32.7 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKP02552.1 - 4.5e-05 23.4 1.9 0.02 14.8 0.1 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RKP02552.1 - 8.4e-05 22.6 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RKP02552.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Sacchrp_dh_NADP PF03435.18 RKP02552.1 - 0.6 10.4 2.8 8.6 6.6 0.2 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Aminotran_1_2 PF00155.21 RKP02553.1 - 1.1e-87 294.5 0.0 1.3e-87 294.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HATPase_c_3 PF13589.6 RKP02555.1 - 0.00087 19.1 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L29 PF00831.23 RKP02556.1 - 9e-18 64.0 1.6 9e-18 64.0 1.6 1.7 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 RKP02556.1 - 0.00099 19.5 1.4 0.00099 19.5 1.4 1.5 2 0 0 2 2 2 1 Snapin/Pallidin Spc7 PF08317.11 RKP02556.1 - 0.057 12.3 1.1 0.078 11.9 1.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3860 PF12976.7 RKP02556.1 - 0.11 12.6 0.7 0.52 10.4 0.2 1.9 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) PQ-loop PF04193.14 RKP02557.1 - 8.7e-33 111.9 6.6 1.8e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 RKP02557.1 - 0.0027 17.7 1.0 0.01 15.9 0.1 2.2 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange TPR_19 PF14559.6 RKP02558.1 - 6.8e-07 29.7 15.2 0.014 15.9 0.0 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat C2 PF00168.30 RKP02558.1 - 0.00028 21.1 0.0 0.0021 18.3 0.0 2.2 2 0 0 2 2 2 1 C2 domain ANAPC3 PF12895.7 RKP02558.1 - 0.0023 18.1 8.7 0.14 12.4 1.4 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKP02558.1 - 0.0027 18.4 15.5 1.5 9.9 0.7 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKP02558.1 - 0.0028 17.6 11.2 0.76 10.0 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKP02558.1 - 0.01 16.2 2.9 0.34 11.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02558.1 - 0.081 12.8 2.6 22 5.1 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 RKP02558.1 - 0.085 13.0 6.6 3.3 7.9 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Rtt106 PF08512.12 RKP02559.1 - 1.5e-20 73.4 0.0 2.1e-19 69.7 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 RKP02559.1 - 2.8e-20 72.0 0.0 6.4e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 RKP02559.1 - 4e-15 56.0 0.0 1.2e-11 44.8 0.0 2.6 2 1 0 2 2 2 2 POB3-like N-terminal PH domain YL1 PF05764.13 RKP02559.1 - 1.6 8.8 8.5 2.2 8.3 8.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Beach PF02138.18 RKP02560.1 - 3.1e-122 407.3 0.0 5.3e-122 406.5 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RKP02560.1 - 7.6e-18 64.5 0.0 1.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 RKP02560.1 - 3.2e-15 56.1 0.0 6.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 RKP02560.1 - 6.9e-10 39.3 1.1 1.2e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 RKP02560.1 - 3.1e-08 33.2 3.5 1.4e-07 31.1 3.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 RKP02560.1 - 2.1e-06 28.3 4.4 0.62 11.0 0.3 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1088 PF06469.11 RKP02560.1 - 0.067 12.9 1.0 0.16 11.7 1.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) WD40 PF00400.32 RKP02562.1 - 5.2e-07 30.3 3.0 0.17 12.8 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02562.1 - 0.084 13.2 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PPP1R32 PF15691.5 RKP02563.1 - 0.0013 17.9 0.3 0.027 13.6 0.2 2.5 3 0 0 3 3 3 2 Protein phosphatase 1 regulatory subunit 32 MOR2-PAG1_N PF14222.6 RKP02564.1 - 5.7e-68 230.2 0.2 2e-59 202.0 0.3 2.3 2 0 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 RKP02564.1 - 2.9e-09 37.2 0.1 2.9e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Cell morphogenesis C-terminal HEAT_2 PF13646.6 RKP02564.1 - 0.0064 16.9 0.2 0.063 13.7 0.2 2.8 1 0 0 1 1 1 1 HEAT repeats MOR2-PAG1_mid PF14228.6 RKP02564.1 - 0.015 13.0 0.6 0.066 10.8 0.3 1.9 2 0 0 2 2 2 0 Cell morphogenesis central region MAP65_ASE1 PF03999.12 RKP02566.1 - 0.0018 17.1 0.1 0.0018 17.1 0.1 2.2 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Bd3614-deam PF14439.6 RKP02567.1 - 1.1 9.4 5.9 4 7.5 1.2 2.9 3 0 0 3 3 3 0 Bd3614-like deaminase Bromodomain PF00439.25 RKP02568.1 - 9.4e-21 73.7 0.0 1e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Bromodomain UPF0016 PF01169.19 RKP02569.1 - 1.7e-36 124.4 26.3 4.2e-18 65.4 10.7 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 RKP02569.1 - 3e-05 23.8 12.5 0.00013 21.7 0.1 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE MaoC_dehydratas PF01575.19 RKP02569.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 MaoC like domain HEAT PF02985.22 RKP02570.1 - 2.8e-17 61.3 13.4 0.00056 19.9 0.0 9.2 10 0 0 10 10 8 3 HEAT repeat HEAT_EZ PF13513.6 RKP02570.1 - 1.1e-15 57.7 12.9 6.9e-13 48.8 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat IBN_N PF03810.19 RKP02570.1 - 1.3e-11 44.2 0.6 3.2e-10 39.8 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 RKP02570.1 - 1.4e-08 35.0 15.4 4.5e-05 23.8 0.0 7.2 4 2 4 8 8 8 3 HEAT repeats IFRD PF05004.13 RKP02570.1 - 2.1e-05 23.8 2.9 0.47 9.5 0.5 4.4 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 RKP02570.1 - 3.1e-05 22.7 0.0 0.00021 20.0 0.0 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.7 RKP02570.1 - 0.00065 19.0 0.4 0.0023 17.2 0.1 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 RKP02570.1 - 0.00084 19.3 4.5 0.0087 16.1 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 RKP02570.1 - 0.0012 17.4 0.4 0.056 11.9 0.0 2.8 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit MMS19_C PF12460.8 RKP02570.1 - 0.0098 15.0 4.4 2.9 6.9 1.2 3.6 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal MOR2-PAG1_C PF14225.6 RKP02570.1 - 0.046 13.6 0.4 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Cell morphogenesis C-terminal CLASP_N PF12348.8 RKP02570.1 - 0.049 13.2 0.3 6.3 6.3 0.0 4.2 3 3 2 5 5 5 0 CLASP N terminal Xpo1 PF08389.12 RKP02570.1 - 0.054 13.5 0.6 3.2 7.8 0.1 3.6 3 1 0 4 4 4 0 Exportin 1-like protein FAT PF02259.23 RKP02571.1 - 2.7e-116 388.6 1.4 2.7e-116 388.6 1.4 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 RKP02571.1 - 1.3e-76 257.7 0.1 2.8e-76 256.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 RKP02571.1 - 8.9e-58 194.7 6.0 3.9e-56 189.4 0.1 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 RKP02571.1 - 4e-44 149.0 2.9 5.9e-44 148.5 0.5 2.7 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 RKP02571.1 - 1.7e-15 56.5 1.7 5.3e-15 54.9 1.7 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 RKP02571.1 - 1.1e-08 34.6 17.8 0.1 12.9 0.0 11.0 12 0 0 12 12 10 1 HEAT repeat Dopey_N PF04118.14 RKP02571.1 - 0.0003 20.0 1.7 0.00086 18.5 1.7 1.7 1 0 0 1 1 1 1 Dopey, N-terminal Sec7_N PF12783.7 RKP02571.1 - 0.004 17.1 5.5 0.18 11.7 0.0 3.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd1 PF12717.7 RKP02571.1 - 0.02 14.9 8.0 2.8 8.0 0.5 5.5 4 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RKP02571.1 - 0.032 14.8 0.0 0.032 14.8 0.0 9.1 8 1 1 9 9 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 RKP02571.1 - 0.04 14.5 3.0 91 3.7 0.0 6.0 5 2 1 6 6 6 0 Vacuolar 14 Fab1-binding region HU-CCDC81_euk_2 PF18289.1 RKP02571.1 - 0.1 12.7 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 Vitellogenin_N PF01347.22 RKP02571.1 - 0.15 10.5 0.0 5.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Lipoprotein amino terminal region UMP1 PF05348.11 RKP02571.1 - 0.17 12.1 0.0 9.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 ANAPC3 PF12895.7 RKP02571.1 - 0.17 12.1 6.4 2.7 8.3 0.2 3.9 4 0 0 4 4 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RIX1 PF08167.12 RKP02571.1 - 0.19 11.5 4.1 37 4.0 0.0 4.7 5 1 0 5 5 4 0 rRNA processing/ribosome biogenesis Baculo_PEP_C PF04513.12 RKP02571.1 - 0.19 11.7 0.0 0.19 11.7 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1180 PF06679.12 RKP02571.1 - 5.6 7.4 7.9 13 6.1 7.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF572 PF04502.13 RKP02572.1 - 1.6e-57 195.7 0.0 2.7e-57 194.9 0.0 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) MCR PF18509.1 RKP02572.1 - 0.051 13.2 0.3 0.12 11.9 0.3 1.6 1 0 0 1 1 1 0 Magnetochrome domain SART-1 PF03343.13 RKP02572.1 - 2.4 6.6 6.2 4.1 5.8 6.2 1.3 1 0 0 1 1 1 0 SART-1 family Adaptin_N PF01602.20 RKP02573.1 - 2.8e-106 356.2 6.9 3.1e-106 356.0 6.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKP02573.1 - 6.5e-46 156.3 1.8 7.3e-44 149.7 0.4 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP02573.1 - 4.1e-15 56.0 14.3 7.6e-07 29.4 0.2 5.4 3 3 2 5 5 5 4 HEAT repeats HEAT PF02985.22 RKP02573.1 - 3.6e-08 33.0 7.0 1.1 9.7 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat RTP1_C1 PF10363.9 RKP02573.1 - 6.4e-06 26.3 4.5 0.0013 18.9 0.4 4.1 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 RKP02573.1 - 0.00057 19.8 7.1 0.13 12.3 0.2 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 RKP02573.1 - 0.0011 19.1 1.4 2 8.6 0.1 3.6 3 1 0 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.13 RKP02573.1 - 0.016 14.7 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Armadillo-like Atx10homo_assoc PF09759.9 RKP02573.1 - 0.042 13.9 0.1 1.8 8.7 0.0 3.3 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 RKP02573.1 - 0.14 12.7 10.1 5.4 7.6 0.5 5.4 4 1 1 5 5 5 0 HEAT-like repeat NPR3 PF03666.13 RKP02574.1 - 5.4e-67 226.6 0.0 2.5e-65 221.1 0.0 2.7 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 RKP02574.1 - 0.11 11.3 0.0 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Nitrogen permease regulator 2 Ax_dynein_light PF10211.9 RKP02575.1 - 7.6e-07 29.3 8.5 7.6e-07 29.3 8.5 2.1 2 0 0 2 2 2 1 Axonemal dynein light chain TSNAXIP1_N PF15739.5 RKP02575.1 - 0.00089 19.6 4.5 0.0024 18.2 0.9 3.2 2 1 1 3 3 3 1 Translin-associated factor X-interacting N-terminus Spc7 PF08317.11 RKP02575.1 - 0.0017 17.3 6.4 0.0017 17.3 6.4 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Taxilin PF09728.9 RKP02575.1 - 0.0021 17.3 7.1 0.0053 16.0 7.1 1.6 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Crystall_4 PF17945.1 RKP02575.1 - 0.0034 17.8 0.0 0.024 15.1 0.0 2.3 2 0 0 2 2 2 1 Beta/Gamma crystallin Sec7 PF01369.20 RKP02575.1 - 0.0095 15.6 0.0 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 Sec7 domain DUF5304 PF17230.2 RKP02575.1 - 0.059 13.6 7.3 3.3 7.9 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5304) Utp12 PF04003.12 RKP02575.1 - 0.12 12.7 4.1 0.69 10.2 0.0 3.5 3 2 0 3 3 3 0 Dip2/Utp12 Family ISG65-75 PF11727.8 RKP02575.1 - 0.85 8.8 5.7 0.72 9.0 3.9 1.8 2 0 0 2 2 2 0 Invariant surface glycoprotein TMF_TATA_bd PF12325.8 RKP02575.1 - 0.95 9.7 16.6 0.048 13.9 3.3 3.8 3 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 RKP02575.1 - 0.97 9.5 5.8 9.4 6.3 0.5 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 RKP02575.1 - 2.6 7.9 6.2 4.3 7.2 2.7 2.6 2 0 0 2 2 2 0 Sec34-like family GAT PF03127.14 RKP02575.1 - 7.1 7.0 7.0 56 4.1 3.3 4.0 3 1 0 3 3 3 0 GAT domain SOR_SNZ PF01680.17 RKP02576.1 - 8.5e-105 349.1 2.3 1.1e-104 348.7 2.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 RKP02576.1 - 4.9e-07 29.3 6.2 2e-05 24.0 1.9 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 RKP02576.1 - 0.0001 21.5 1.0 0.13 11.3 0.1 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 RKP02576.1 - 0.0042 16.6 0.1 0.32 10.4 0.1 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 RKP02576.1 - 0.01 15.1 1.6 0.12 11.6 0.1 2.7 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 RKP02576.1 - 0.027 13.6 0.1 0.6 9.2 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 RKP02576.1 - 0.083 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 RKP02576.1 - 0.19 11.1 5.0 0.82 9.0 0.8 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase AA_permease_2 PF13520.6 RKP02577.1 - 5.4e-74 249.5 41.9 6.2e-74 249.3 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RKP02577.1 - 2.1e-30 105.8 33.9 2.7e-30 105.4 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 RKP02580.1 - 2.8e-71 240.0 0.0 3.3e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02580.1 - 1.8e-35 122.5 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP02580.1 - 0.00017 21.0 0.5 0.00028 20.3 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP02580.1 - 0.00037 19.6 0.1 0.00055 19.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKP02580.1 - 0.00098 19.1 0.6 0.013 15.4 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP02580.1 - 0.079 12.3 0.1 0.87 8.8 0.0 2.1 1 1 1 2 2 2 0 Kinase-like Pkinase PF00069.25 RKP02581.1 - 2.2e-71 240.3 0.0 2.6e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02581.1 - 1.3e-33 116.4 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP02581.1 - 0.0098 15.3 0.2 0.017 14.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP02581.1 - 0.021 13.8 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RKP02581.1 - 0.024 14.6 0.7 0.27 11.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family 5_nucleotid_C PF02872.18 RKP02582.1 - 4.3e-37 127.7 0.0 6.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 RKP02582.1 - 5.1e-05 23.9 0.0 8.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Imm35 PF15567.6 RKP02582.1 - 0.072 13.3 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 35 Chitin_synth_2 PF03142.15 RKP02583.1 - 1.2e-14 53.9 0.0 1.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase CAP_N PF01213.19 RKP02583.1 - 6.7 6.1 5.3 32 3.8 2.1 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TFIID-18kDa PF02269.16 RKP02584.1 - 1.1e-25 89.4 1.0 2.1e-23 82.2 0.0 2.7 2 1 1 3 3 3 2 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 RKP02584.1 - 1.9e-05 24.7 0.1 4.2e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 RKP02584.1 - 0.0011 19.1 0.6 0.3 11.4 0.1 3.1 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GCIP PF13324.6 RKP02584.1 - 0.062 12.9 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Hexose_dehydrat PF03559.14 RKP02584.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase Pkinase PF00069.25 RKP02585.1 - 8.2e-56 189.3 0.0 7e-40 137.0 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02585.1 - 8.1e-24 84.3 0.0 2e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02585.1 - 5e-07 29.3 0.0 1.1e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP02585.1 - 9.1e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKP02585.1 - 0.00073 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKP02585.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family VWA_2 PF13519.6 RKP02586.1 - 5.9e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 RKP02586.1 - 0.18 12.0 0.0 0.58 10.4 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Nsp1_C PF05064.13 RKP02587.1 - 1.2e-24 86.3 2.3 1.2e-24 86.3 2.3 2.1 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 RKP02587.1 - 7.2e-15 55.6 66.2 2.4e-09 37.9 21.3 4.9 1 1 3 4 4 4 3 Nucleoporin FG repeat region DUF4600 PF15372.6 RKP02587.1 - 0.03 14.7 0.3 6.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) EcsC PF12787.7 RKP02587.1 - 0.038 13.7 0.8 0.13 11.9 0.8 2.0 1 0 0 1 1 1 0 EcsC protein family Med30 PF11315.8 RKP02587.1 - 0.074 13.3 0.7 0.23 11.7 0.8 1.7 1 1 0 1 1 1 0 Mediator complex subunit 30 HTH_37 PF13744.6 RKP02587.1 - 0.11 12.5 0.4 0.37 10.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Allexi_40kDa PF05549.11 RKP02587.1 - 0.12 11.9 4.5 0.29 10.6 0.4 3.0 3 0 0 3 3 3 0 Allexivirus 40kDa protein BNR_3 PF13859.6 RKP02587.1 - 0.13 11.5 0.6 0.18 11.0 0.6 1.2 1 0 0 1 1 1 0 BNR repeat-like domain BLOC1_2 PF10046.9 RKP02587.1 - 0.25 11.7 9.2 6.2 7.2 1.2 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 RKP02587.1 - 0.5 10.6 11.4 5.3 7.4 1.9 3.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 RKP02587.1 - 0.85 9.7 9.1 2.6 8.1 2.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4254 PF14063.6 RKP02587.1 - 1.1 9.1 5.3 1.8 8.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) eIF3_N PF09440.10 RKP02587.1 - 3.1 8.2 6.3 0.44 11.0 1.7 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain UPF0242 PF06785.11 RKP02587.1 - 3.5 7.7 6.9 0.75 9.9 1.9 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TFIIA PF03153.13 RKP02587.1 - 3.9 7.4 16.2 4.8 7.1 15.6 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IMD PF08397.11 RKP02588.1 - 0.011 15.2 5.7 0.024 14.0 0.2 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain Phage_TAC_4 PF08748.11 RKP02588.1 - 0.096 13.0 0.3 0.096 13.0 0.3 1.5 2 0 0 2 2 2 0 Phage tail assembly chaperone Mon2_C PF16206.5 RKP02589.1 - 1.2e-51 175.9 0.0 1.1e-27 96.6 0.0 4.3 4 0 0 4 4 4 4 C-terminal region of Mon2 protein Sec7_N PF12783.7 RKP02589.1 - 3.6e-45 153.7 0.4 1.4e-44 151.8 0.4 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 RKP02589.1 - 5.7e-41 140.1 0.0 2e-39 135.1 0.0 3.1 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 RKP02589.1 - 0.063 13.1 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Dscam_C PF12355.8 RKP02589.1 - 3 8.8 8.2 1.4 9.9 1.2 3.1 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal GIY-YIG PF01541.24 RKP02590.1 - 1.8e-10 41.0 0.0 2.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 RKP02590.1 - 0.0089 16.2 0.8 0.019 15.1 0.2 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RKP02590.1 - 0.2 11.9 1.8 0.63 10.3 1.9 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Isochorismatase PF00857.20 RKP02591.1 - 4.5e-25 88.8 0.2 6e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 Isochorismatase family Glyco_transf_4 PF13439.6 RKP02591.1 - 0.0012 18.9 0.0 0.1 12.6 0.0 2.7 2 1 1 3 3 3 1 Glycosyltransferase Family 4 LAG1-DNAbind PF09271.11 RKP02592.1 - 1.5e-15 58.1 0.0 2.9e-14 54.0 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 RKP02592.1 - 2.7e-12 47.2 0.0 5.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain SNARE PF05739.19 RKP02593.1 - 3.9e-10 39.6 0.2 1.5e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 RKP02593.1 - 0.00037 20.2 2.2 0.00059 19.6 2.2 1.3 1 0 0 1 1 1 1 Syntaxin AAA_PrkA PF08298.11 RKP02593.1 - 0.0061 15.5 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain DUF1043 PF06295.12 RKP02593.1 - 0.034 14.2 2.3 0.036 14.1 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DMSP_lyase PF16867.5 RKP02593.1 - 0.11 12.1 0.6 0.14 11.8 0.6 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Tubulin PF00091.25 RKP02594.1 - 1.5e-69 234.1 0.0 2.3e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RKP02594.1 - 2.5e-41 140.8 0.3 6.9e-41 139.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RKP02594.1 - 2.5e-05 24.5 0.0 6.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RKP02594.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Phosphodiest PF01663.22 RKP02595.1 - 1.6e-10 41.2 2.0 2.4e-10 40.5 1.0 1.5 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RKP02595.1 - 0.0038 16.7 0.2 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 Sulfatase hNIFK_binding PF12196.8 RKP02595.1 - 0.26 10.8 1.8 5.4 6.6 0.7 2.6 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Ribosomal_S3_C PF00189.20 RKP02596.1 - 0.0081 16.6 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Rad51 PF08423.11 RKP02597.1 - 3e-15 56.2 1.4 7.4e-15 54.9 0.2 1.8 1 1 1 2 2 2 1 Rad51 HHH_5 PF14520.6 RKP02597.1 - 4.5e-05 24.0 0.8 8e-05 23.2 0.8 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain NRD1_2 PF01995.16 RKP02597.1 - 0.00067 19.0 0.2 0.0009 18.6 0.2 1.1 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 HlyD_D4 PF16572.5 RKP02597.1 - 0.12 12.2 0.6 1.9 8.4 0.1 2.3 1 1 1 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB Utp12 PF04003.12 RKP02598.1 - 0.21 11.9 1.1 0.78 10.1 0.5 2.3 2 1 0 2 2 2 0 Dip2/Utp12 Family AMP-binding PF00501.28 RKP02599.1 - 5.1e-33 114.3 0.1 1.7e-31 109.3 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 RKP02599.1 - 4.6e-28 98.1 0.0 7.5e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 RKP02599.1 - 0.0052 16.3 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RKP02599.1 - 0.11 12.4 1.2 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RKP02599.1 - 0.24 10.7 0.3 0.55 9.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CX9C PF16860.5 RKP02600.1 - 8.7e-06 25.6 0.9 0.041 13.9 0.1 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 RKP02600.1 - 0.00048 20.3 0.7 0.0017 18.6 0.7 1.7 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) CHCH PF06747.13 RKP02600.1 - 0.0069 16.5 0.6 0.16 12.1 0.1 2.0 2 0 0 2 2 2 1 CHCH domain Ndufs5 PF10200.9 RKP02600.1 - 0.014 15.6 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 RKP02600.1 - 0.021 14.8 1.6 0.52 10.4 0.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 RKP02600.1 - 0.039 14.2 0.4 0.048 13.9 0.4 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Lactamase_B PF00753.27 RKP02601.1 - 1.2e-07 31.9 3.3 1.5e-06 28.4 0.1 3.5 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RKP02601.1 - 0.00028 20.5 0.5 0.0013 18.3 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SUIM_assoc PF16619.5 RKP02601.1 - 0.046 13.8 9.7 0.12 12.5 9.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 RKP02601.1 - 0.2 11.2 11.1 0.31 10.6 11.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF702 PF05142.12 RKP02601.1 - 0.24 11.9 4.3 0.56 10.7 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.13 RKP02601.1 - 0.26 11.3 8.2 0.56 10.1 8.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phage_Coat_B PF05356.11 RKP02602.1 - 0.016 15.1 0.4 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 Phage Coat protein B TPPK_C PF12555.8 RKP02602.1 - 3 8.0 9.0 0.21 11.7 1.3 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal FHA PF00498.26 RKP02603.1 - 6.6e-12 45.6 0.0 1.3e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RKP02603.1 - 0.0019 18.5 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4793 PF16041.5 RKP02604.1 - 4.9e-05 23.4 0.0 9.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) KRTAP PF11759.8 RKP02604.1 - 0.02 15.4 17.2 0.073 13.6 17.2 1.9 1 0 0 1 1 1 0 Keratin-associated matrix Chordopox_A13L PF05961.11 RKP02604.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CLTH PF10607.9 RKP02605.1 - 2.1e-19 69.9 0.0 4.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 RKP02605.1 - 5.2e-05 23.2 0.1 9.6e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Pex19 PF04614.12 RKP02605.1 - 0.038 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Pex19 protein family zf-C3HC4_4 PF15227.6 RKP02605.1 - 0.045 13.9 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CAP_N PF01213.19 RKP02605.1 - 0.064 12.7 0.7 0.11 12.0 0.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RasGEF PF00617.19 RKP02606.1 - 4.1e-50 170.4 0.0 5.8e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RKP02606.1 - 1.4e-19 70.3 0.0 2.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif CENP-B_dimeris PF09026.10 RKP02607.1 - 0.0092 16.3 6.4 0.0092 16.3 6.4 3.3 3 0 0 3 3 3 2 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RKP02607.1 - 0.01 15.6 4.5 0.01 15.6 4.5 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 RKP02607.1 - 0.018 14.5 17.1 0.13 11.7 5.4 2.2 2 0 0 2 2 2 0 SDA1 RRN3 PF05327.11 RKP02607.1 - 0.15 10.6 10.7 1.8 7.0 9.3 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 AF-4 PF05110.13 RKP02607.1 - 0.26 9.3 11.8 0.48 8.5 11.8 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM176 PF14851.6 RKP02607.1 - 0.87 9.2 13.9 8.2 6.1 2.5 3.4 3 0 0 3 3 3 0 FAM176 family Myc_N PF01056.18 RKP02607.1 - 3.8 7.3 16.9 0.11 12.4 0.7 3.1 2 1 1 3 3 3 0 Myc amino-terminal region RNA_polI_A34 PF08208.11 RKP02608.1 - 2.8e-18 66.8 0.9 1.2e-17 64.7 0.9 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 SMC_Nse1 PF07574.13 RKP02609.1 - 6.1e-16 58.9 0.0 6.2e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex C1_1 PF00130.22 RKP02609.1 - 0.98 9.4 12.3 0.2 11.6 8.6 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ACT_5 PF13710.6 RKP02611.1 - 0.67 9.8 6.0 0.39 10.6 0.6 3.3 4 0 0 4 4 4 0 ACT domain Seipin PF06775.14 RKP02612.1 - 7.1e-45 153.5 0.0 1.5e-44 152.5 0.0 1.5 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF2628 PF10947.8 RKP02612.1 - 0.00051 20.3 0.8 0.0013 19.0 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) HemY_N PF07219.13 RKP02612.1 - 3.8 7.7 9.5 59 3.9 9.5 2.6 1 1 0 1 1 1 0 HemY protein N-terminus FAD-oxidase_C PF02913.19 RKP02613.1 - 3.2e-54 184.2 0.0 4.6e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 RKP02613.1 - 3.8e-35 120.6 3.5 7.5e-35 119.7 3.5 1.4 1 0 0 1 1 1 1 FAD binding domain ATG11 PF10377.9 RKP02614.1 - 5.4e-11 42.7 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.12 RKP02614.1 - 7.6e-06 25.3 0.1 7.6e-06 25.3 0.1 2.3 3 1 0 3 3 3 1 Autophagy protein Apg17 PKcGMP_CC PF16808.5 RKP02614.1 - 0.0097 15.7 0.3 0.03 14.2 0.3 1.8 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_L29 PF00831.23 RKP02614.1 - 0.065 13.2 0.3 0.4 10.7 0.7 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein GAS PF13851.6 RKP02614.1 - 0.084 12.2 1.7 0.72 9.2 0.3 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CC2-LZ PF16516.5 RKP02614.1 - 0.37 11.2 2.2 27 5.2 0.4 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 RKP02614.1 - 0.4 9.5 3.0 1.5 7.7 0.4 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 RKP02614.1 - 1.8 9.2 15.9 11 6.7 2.9 5.5 6 0 0 6 6 6 0 SlyX Lebercilin PF15619.6 RKP02614.1 - 1.9 8.1 9.1 0.77 9.4 1.8 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 RKP02614.1 - 2.5 8.4 6.1 3.3 7.9 0.6 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.6 RKP02614.1 - 8.2 6.6 12.4 6 7.0 0.7 3.4 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit OPT PF03169.15 RKP02615.1 - 3.3e-122 409.2 51.3 3.8e-122 409.0 51.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MerE PF05052.12 RKP02615.1 - 3.1 7.8 7.7 1 9.4 3.6 2.3 2 0 0 2 2 2 0 MerE protein DUF995 PF06191.12 RKP02616.1 - 6.8 6.4 5.7 15 5.2 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF995) CUE PF02845.16 RKP02617.1 - 8e-10 38.2 0.0 1.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 RKP02617.1 - 0.0041 16.7 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 DMRTA motif Ribosomal_L2_C PF03947.18 RKP02618.1 - 2.4e-48 163.5 2.9 3.5e-48 163.0 2.9 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RKP02618.1 - 8e-15 54.6 0.0 2.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TT_ORF2a PF08197.11 RKP02618.1 - 0.014 15.3 0.9 0.037 14.0 0.9 1.7 1 0 0 1 1 1 0 pORF2a truncated protein RCC1 PF00415.18 RKP02619.1 - 1.5e-38 131.1 13.6 6.5e-10 39.5 0.0 6.8 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKP02619.1 - 6.1e-24 83.3 21.9 3.9e-06 26.5 0.1 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Guanylate_cyc PF00211.20 RKP02621.1 - 1.3e-16 60.8 0.1 4.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain zf-C2HC_2 PF13913.6 RKP02622.1 - 3.8e-19 68.1 6.5 4e-09 36.2 0.1 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 RKP02622.1 - 0.00077 19.8 3.7 0.58 10.7 0.2 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02622.1 - 0.17 12.8 5.8 8.8 7.5 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 RKP02622.1 - 0.72 10.0 3.4 18 5.6 0.4 2.2 2 0 0 2 2 2 0 FYVE zinc finger Sgf11 PF08209.11 RKP02622.1 - 1.1 8.9 5.6 0.55 9.8 1.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_11 PF16622.5 RKP02622.1 - 4.3 7.2 6.0 3 7.7 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type Memo PF01875.17 RKP02623.1 - 1.6e-67 227.6 0.0 1.8e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DnaJ_C PF01556.18 RKP02626.1 - 4.3e-37 127.5 0.0 5.8e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKP02626.1 - 2.4e-26 91.6 1.9 3.5e-26 91.1 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RKP02626.1 - 9.6e-15 54.7 14.2 1.8e-14 53.9 14.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 RKP02626.1 - 7.3e-06 26.0 5.5 0.0018 18.3 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 RKP02626.1 - 0.0014 18.6 11.7 0.017 15.1 1.8 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 RKP02626.1 - 0.084 13.4 4.5 0.19 12.2 4.5 1.6 1 1 0 1 1 1 0 Cytochrome c3 DZR PF12773.7 RKP02626.1 - 0.2 11.7 9.0 0.75 9.9 9.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 RKP02626.1 - 0.3 10.8 7.1 3.1 7.4 0.9 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF5351 PF17302.2 RKP02626.1 - 3.3 8.0 18.6 5 7.4 0.3 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Formyl_trans_N PF00551.19 RKP02627.1 - 9.1e-41 139.6 0.0 2.8e-40 138.0 0.0 1.8 1 1 0 1 1 1 1 Formyl transferase BTB PF00651.31 RKP02628.1 - 5.7e-05 23.3 0.0 0.0039 17.4 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain YL1 PF05764.13 RKP02628.1 - 0.052 13.7 2.7 0.13 12.4 2.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein PRK PF00485.18 RKP02629.1 - 7.7e-37 127.0 0.0 8.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 RKP02629.1 - 0.0015 18.2 1.7 0.48 10.1 0.2 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase Spore_II_R PF09551.10 RKP02629.1 - 0.12 12.9 0.1 0.29 11.6 0.0 1.6 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Tom37 PF10568.9 RKP02630.1 - 3.4e-24 85.5 0.0 4.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 RKP02630.1 - 1.6e-21 76.9 0.0 2.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 RKP02630.1 - 4.8e-11 42.3 0.0 9.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 RKP02630.1 - 7.1e-06 26.0 1.5 1.2e-05 25.2 0.7 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RKP02630.1 - 0.0027 18.1 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lectin_leg-like PF03388.13 RKP02631.1 - 2.4e-41 141.6 0.0 2.8e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 RKP02631.1 - 0.0084 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin DUF155 PF02582.14 RKP02632.1 - 6.2e-53 179.5 0.0 8.2e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3377 PF11857.8 RKP02632.1 - 0.034 14.1 2.0 0.062 13.2 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ribosomal_S9 PF00380.19 RKP02633.1 - 1.7e-34 118.9 0.7 2.2e-34 118.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RRM_1 PF00076.22 RKP02634.1 - 1.1e-12 47.5 0.0 1.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 RKP02634.1 - 1.7e-08 34.1 2.4 2.9e-08 33.4 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 RKP02634.1 - 0.00035 20.2 1.9 0.0007 19.2 1.9 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 RKP02634.1 - 0.0012 18.6 1.4 0.0022 17.8 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RKP02634.1 - 0.016 15.2 0.7 0.026 14.5 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_3 PF08777.11 RKP02634.1 - 0.017 15.2 0.2 0.025 14.6 0.2 1.2 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 RKP02634.1 - 0.036 14.1 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RKP02634.1 - 0.11 12.7 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif DUF1242 PF06842.12 RKP02635.1 - 3.7e-20 71.4 1.5 4.8e-20 71.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) CCDC32 PF14989.6 RKP02636.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing 32 SRA1 PF07304.11 RKP02637.1 - 8.7e-12 45.0 0.0 8.7e-12 45.0 0.0 3.6 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 RKP02637.1 - 2.7e-09 37.5 10.2 0.035 15.0 0.5 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat CDP-OH_P_transf PF01066.21 RKP02638.1 - 2.6e-14 53.7 0.9 2.6e-14 53.7 0.9 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase LRR_RI_capping PF18779.1 RKP02639.1 - 0.09 12.4 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat PseudoU_synth_2 PF00849.22 RKP02641.1 - 6.4e-23 81.6 0.0 1.1e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Pterin_4a PF01329.19 RKP02641.1 - 0.067 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase PhoLip_ATPase_C PF16212.5 RKP02642.1 - 5e-77 259.0 19.5 5e-77 259.0 19.5 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKP02642.1 - 2.1e-21 75.4 6.3 5.7e-21 74.0 6.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RKP02642.1 - 1.7e-10 40.8 0.0 5.8e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RKP02642.1 - 7.1e-09 36.2 5.8 4.9e-05 23.7 2.8 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RKP02642.1 - 4.6e-07 29.5 0.3 4.2e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RKP02642.1 - 0.0011 18.8 0.4 0.0041 16.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_12 PF13087.6 RKP02643.1 - 6.3e-58 195.7 0.0 9.5e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.10 RKP02643.1 - 3.9e-55 186.0 0.0 9.9e-55 184.7 0.0 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 RKP02643.1 - 5e-44 151.0 0.5 8.3e-28 97.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 RKP02643.1 - 2.2e-22 79.1 0.0 1.3e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 RKP02643.1 - 2.1e-13 50.4 0.2 1.7e-12 47.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RKP02643.1 - 1.1e-08 35.5 0.0 2.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RKP02643.1 - 0.034 13.5 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 RKP02643.1 - 0.043 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 RKP02643.1 - 0.057 12.7 0.1 0.057 12.7 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 RKP02643.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Helicase PhoH PF02562.16 RKP02643.1 - 0.16 11.4 0.0 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.7 RKP02643.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Cwf_Cwc_15 PF04889.12 RKP02643.1 - 1 9.1 6.6 2.2 7.9 6.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 RKP02643.1 - 3 7.7 5.4 6.1 6.7 5.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RKP02643.1 - 9.3 4.2 5.5 14 3.6 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glyco_trans_1_4 PF13692.6 RKP02644.1 - 9.6e-08 32.5 0.0 2.8e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RKP02644.1 - 8.4e-06 25.9 0.8 4.2e-05 23.6 0.8 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RKP02644.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 SBDS PF01172.18 RKP02645.1 - 8.9e-34 115.4 1.5 1.6e-33 114.7 1.5 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 RKP02645.1 - 3.2e-31 107.7 1.0 4.3e-31 107.3 0.3 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain 2-Hacid_dh_C PF02826.19 RKP02645.1 - 0.0011 18.3 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M57 PF12388.8 RKP02645.1 - 0.16 11.5 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase HMMR_C PF15908.5 RKP02645.1 - 0.2 11.9 4.0 0.17 12.1 1.8 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal EXS PF03124.14 RKP02646.1 - 8.9e-59 199.5 0.0 4.5e-28 98.5 0.0 2.8 2 1 0 2 2 2 2 EXS family DinB_2 PF12867.7 RKP02646.1 - 4 8.0 8.4 0.22 12.0 0.4 2.6 2 1 0 2 2 2 0 DinB superfamily HMGL-like PF00682.19 RKP02647.1 - 2.7e-92 309.1 0.4 3.6e-92 308.7 0.4 1.1 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 RKP02647.1 - 3e-21 75.7 0.0 5.2e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Peptidase_A22B PF04258.13 RKP02648.1 - 4.7e-78 262.6 6.8 7.8e-78 261.9 6.8 1.3 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 RKP02648.1 - 3.3e-08 33.3 7.9 7.9e-08 32.1 7.9 1.6 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease IspA PF04279.15 RKP02648.1 - 0.0094 16.1 2.1 1.5 9.0 0.1 2.2 2 0 0 2 2 2 2 Intracellular septation protein A Presenilin PF01080.17 RKP02648.1 - 0.015 14.1 1.7 0.015 14.1 1.7 2.5 2 1 0 2 2 2 0 Presenilin Spt20 PF12090.8 RKP02649.1 - 0.025 14.2 22.9 0.41 10.2 13.2 2.3 2 0 0 2 2 2 0 Spt20 family Calc_CGRP_IAPP PF00214.19 RKP02649.1 - 0.34 11.3 6.8 0.033 14.5 1.5 2.1 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Ndc1_Nup PF09531.10 RKP02649.1 - 2.2 6.9 19.8 0.63 8.7 8.2 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup HIM1 PF08732.10 RKP02650.1 - 3.3e-06 26.7 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 RKP02650.1 - 8e-06 25.9 1.0 1.1e-05 25.4 0.2 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 RKP02650.1 - 7.6e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RKP02650.1 - 0.0046 16.6 0.3 1.3 8.5 0.2 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 RKP02650.1 - 0.047 13.6 0.2 0.096 12.6 0.0 1.7 2 0 0 2 2 2 0 KR domain Mannosyl_trans PF05007.13 RKP02651.1 - 1.2e-70 238.3 11.6 2.1e-70 237.6 11.6 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 RKP02651.1 - 1.3e-12 47.5 3.5 1.3e-12 47.5 3.5 2.6 2 1 1 3 3 3 1 GPI transamidase subunit PIG-U DnaJ PF00226.31 RKP02652.1 - 1.1e-16 60.7 0.1 2.4e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3950 PF13132.6 RKP02652.1 - 3 7.7 4.7 24 4.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) cNMP_binding PF00027.29 RKP02653.1 - 7.7e-19 67.6 0.1 3.4e-11 43.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Hydrolase_4 PF12146.8 RKP02656.1 - 1.4e-10 40.8 0.4 3.4e-07 29.8 0.5 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKP02656.1 - 2.6e-08 33.9 0.2 6.2e-05 22.8 0.9 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RKP02656.1 - 1.3e-05 26.0 8.6 2.2e-05 25.2 8.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 RKP02656.1 - 0.0081 15.2 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 RKP02656.1 - 0.011 14.4 0.2 0.029 13.0 0.1 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 RKP02656.1 - 0.028 14.4 0.0 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 RKP02656.1 - 0.067 13.0 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LIP PF03583.14 RKP02656.1 - 0.073 12.4 0.0 7.5 5.8 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.18 RKP02656.1 - 0.089 12.3 0.0 0.8 9.2 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family MRF_C1 PF13887.6 RKP02657.1 - 0.17 11.1 0.3 3.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Phage_term_smal PF05944.12 RKP02657.1 - 0.17 11.9 2.3 0.19 11.7 0.5 1.8 2 0 0 2 2 2 0 Phage small terminase subunit WD40 PF00400.32 RKP02659.1 - 6.2e-44 147.1 15.6 3e-06 27.9 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 RKP02659.1 - 2e-07 30.8 2.3 5e-07 29.5 2.3 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 RKP02659.1 - 3.4e-06 27.3 4.4 2.3 8.6 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP02659.1 - 1.1e-05 24.3 5.4 0.44 9.1 0.0 4.8 4 1 0 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RKP02659.1 - 5.6e-05 22.6 0.0 0.11 11.8 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 RKP02659.1 - 6.7e-05 22.6 4.5 0.0063 16.1 1.7 2.9 1 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 RKP02659.1 - 0.0075 16.7 2.8 4.4 7.9 0.0 4.8 7 0 0 7 7 5 1 PQQ-like domain DUF1513 PF07433.11 RKP02659.1 - 0.013 14.6 0.0 0.15 11.1 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) F-box PF00646.33 RKP02659.1 - 0.022 14.6 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 F-box domain DUF5046 PF16465.5 RKP02659.1 - 0.024 14.1 0.0 8.7 5.7 0.0 3.4 1 1 1 4 4 4 0 Domain of unknown function (DUF5046) PQQ PF01011.21 RKP02659.1 - 0.036 14.0 0.5 8.9 6.4 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat PALB2_WD40 PF16756.5 RKP02659.1 - 0.078 11.9 0.2 3.3 6.6 0.0 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 RKP02659.1 - 0.087 12.5 0.0 9.6 5.8 0.0 3.0 3 0 0 3 3 3 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 RKP02659.1 - 0.17 10.8 0.2 24 3.7 0.0 3.4 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YEATS PF03366.16 RKP02660.1 - 3.7e-32 110.1 0.8 4.9e-32 109.7 0.8 1.2 1 0 0 1 1 1 1 YEATS family IMS PF00817.20 RKP02661.1 - 6.5e-40 136.6 0.3 1.4e-39 135.5 0.3 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RKP02661.1 - 1.5e-13 51.4 0.0 4.6e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 RKP02661.1 - 1.6e-07 31.6 1.4 2.1e-07 31.3 0.1 1.8 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain BRCT PF00533.26 RKP02661.1 - 6.4e-07 29.7 0.0 1.9e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain UBM PF14377.6 RKP02661.1 - 2.5e-06 26.7 0.8 0.0024 17.3 0.4 3.8 3 0 0 3 3 3 1 Ubiquitin binding region IMS_HHH PF11798.8 RKP02661.1 - 0.00049 20.3 0.0 0.0072 16.6 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 RKP02661.1 - 0.0018 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 RKP02661.1 - 0.0095 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF1805 PF08827.11 RKP02661.1 - 0.087 13.2 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) EF-hand_6 PF13405.6 RKP02662.1 - 1.4e-08 33.9 0.1 0.0017 18.1 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 RKP02662.1 - 4.3e-08 33.5 0.0 0.0027 18.1 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 RKP02662.1 - 1.1e-05 24.6 0.1 0.0098 15.4 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 RKP02662.1 - 0.018 14.5 0.0 19 4.9 0.0 3.5 4 0 0 4 4 4 0 EF hand EF-hand_8 PF13833.6 RKP02662.1 - 0.025 14.4 0.1 17 5.4 0.0 3.4 3 1 1 4 4 4 0 EF-hand domain pair PG_binding_1 PF01471.18 RKP02662.1 - 0.051 13.8 0.1 0.38 11.0 0.0 2.3 2 1 0 2 2 2 0 Putative peptidoglycan binding domain WD40 PF00400.32 RKP02665.1 - 1.2e-27 95.5 18.3 2.7e-05 24.9 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02665.1 - 3.8e-12 46.3 0.3 0.039 14.3 0.0 4.7 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain RIO1 PF01163.22 RKP02666.1 - 5.7e-66 221.7 0.0 5.7e-66 221.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 RKP02666.1 - 0.00017 21.6 0.1 0.0045 16.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family CDC45 PF02724.14 RKP02666.1 - 0.0048 15.3 2.1 0.0054 15.1 2.1 1.2 1 0 0 1 1 1 1 CDC45-like protein Kdo PF06293.14 RKP02666.1 - 0.0086 15.4 0.3 2.6 7.4 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SEEEED PF14797.6 RKP02666.1 - 0.19 11.9 12.9 0.29 11.3 12.9 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Cys_Met_Meta_PP PF01053.20 RKP02667.1 - 4.8e-121 403.9 0.0 5.6e-121 403.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RKP02667.1 - 0.00019 20.8 0.0 0.001 18.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Striatin PF08232.12 RKP02668.1 - 8.4e-39 133.6 0.0 1.3e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 RKP02668.1 - 8.5e-20 70.7 11.9 0.00096 19.9 0.2 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat HTH_53 PF18606.1 RKP02668.1 - 0.00011 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Zap helix turn helix N-terminal domain NUDE_C PF04880.13 RKP02668.1 - 0.58 10.6 3.2 13 6.2 0.0 2.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Esterase PF00756.20 RKP02669.1 - 3.9e-47 161.0 0.0 4.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 RKP02669.1 - 2.8e-09 36.8 1.0 1.4e-08 34.5 1.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 RKP02669.1 - 0.00052 19.4 0.1 0.0016 17.8 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 RKP02669.1 - 0.00094 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 RKP02669.1 - 0.0037 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 RKP02669.1 - 0.0056 15.7 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.25 RKP02669.1 - 0.017 15.0 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 RKP02669.1 - 1.3 9.5 9.5 1.7 9.2 8.7 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family RRM_1 PF00076.22 RKP02670.1 - 0.00044 20.0 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP PF00188.26 RKP02671.1 - 1.2e-14 55.2 0.1 3e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Ribosomal_L1 PF00687.21 RKP02673.1 - 6.9e-19 68.4 0.0 9.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-Tim10_DDP PF02953.15 RKP02674.1 - 3.2e-20 71.5 0.9 3.7e-20 71.3 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Myb_DNA-bind_5 PF13873.6 RKP02674.1 - 0.055 13.6 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Na_H_Exchanger PF00999.21 RKP02675.1 - 3.1e-14 52.6 24.6 8.1e-07 28.2 3.4 3.3 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family DUF3613 PF12266.8 RKP02676.1 - 0.5 10.2 4.9 1.2 8.9 0.4 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3613) DUF2431 PF10354.9 RKP02677.1 - 9.9e-23 81.2 0.0 1.4e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2 PF00096.26 RKP02677.1 - 0.0001 22.5 18.2 0.23 12.0 0.1 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RKP02677.1 - 0.00021 21.5 5.3 0.076 13.3 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RKP02677.1 - 0.0011 19.7 23.1 0.21 12.5 0.5 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 RKP02677.1 - 0.017 15.4 3.7 0.17 12.1 0.1 3.4 3 1 0 3 3 3 0 zinc-ribbon zf-met PF12874.7 RKP02677.1 - 0.034 14.6 7.3 13 6.3 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 RKP02677.1 - 0.062 14.0 4.8 0.087 13.5 0.1 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 RKP02677.1 - 0.09 12.4 6.6 9.5 5.9 0.1 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 RKP02677.1 - 0.11 12.1 0.6 16 5.1 0.0 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.7 RKP02677.1 - 0.38 10.8 4.6 7.8 6.6 0.2 2.9 2 2 0 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 RKP02677.1 - 1 9.8 4.7 10 6.5 0.2 3.2 4 0 0 4 4 4 0 C1 domain Zn-ribbon_8 PF09723.10 RKP02677.1 - 1.1 9.4 7.4 3.7 7.7 0.0 4.0 4 0 0 4 4 4 0 Zinc ribbon domain Desulfoferrod_N PF06397.12 RKP02677.1 - 1.5 8.5 3.5 2.2 8.0 1.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2256 PF10013.9 RKP02677.1 - 3.6 7.8 4.5 7 6.9 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) LIM PF00412.22 RKP02677.1 - 4.6 7.6 6.9 27 5.1 0.0 3.6 4 0 0 4 4 4 0 LIM domain Radical_SAM PF04055.21 RKP02678.1 - 1.1e-11 45.4 0.0 1.7e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 RKP02678.1 - 0.0094 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Trypan_PARP PF05887.11 RKP02679.1 - 0.049 13.6 5.2 0.11 12.5 5.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_LMP1 PF05297.11 RKP02679.1 - 0.14 11.3 4.0 0.25 10.5 4.0 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pkinase PF00069.25 RKP02680.1 - 6.3e-56 189.7 0.0 7e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02680.1 - 2.1e-46 158.3 0.0 2.6e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02680.1 - 6.6e-06 25.6 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP02680.1 - 8.7e-06 24.8 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKP02680.1 - 0.0082 15.5 0.1 0.077 12.3 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RKP02680.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 RKP02680.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF515 PF04415.12 RKP02682.1 - 2.4 6.4 7.0 2.1 6.6 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) YabA PF06156.13 RKP02684.1 - 2 9.1 29.3 0.43 11.2 1.1 5.1 4 1 2 6 6 6 0 Initiation control protein YabA Pkinase PF00069.25 RKP02686.1 - 5.6e-70 235.7 0.0 7e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02686.1 - 1.8e-45 155.3 0.0 2.5e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 RKP02686.1 - 1.4e-20 73.4 0.0 3.3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 RKP02686.1 - 5.3e-08 32.5 0.0 1.1e-07 31.4 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKP02686.1 - 6e-07 28.6 0.0 1.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKP02686.1 - 0.04 13.8 0.1 0.61 10.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1513 PF07433.11 RKP02686.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Kdo PF06293.14 RKP02686.1 - 0.13 11.6 0.3 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family IGPD PF00475.18 RKP02687.1 - 1.4e-62 210.3 1.4 1.6e-62 210.0 1.4 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SGP PF17228.2 RKP02688.1 - 0.00037 21.3 9.2 0.00084 20.1 9.2 1.5 1 0 0 1 1 1 1 Sulphur globule protein KRTAP PF11759.8 RKP02688.1 - 0.00037 21.0 17.0 0.00095 19.7 17.0 1.7 1 0 0 1 1 1 1 Keratin-associated matrix MarC PF01914.17 RKP02688.1 - 0.16 11.4 0.5 0.23 10.8 0.5 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein EB PF01683.18 RKP02688.1 - 1.3 9.4 5.0 6.3 7.2 5.0 2.2 1 1 0 1 1 1 0 EB module Complex1_LYR_1 PF13232.6 RKP02689.1 - 0.058 14.0 0.1 0.15 12.6 0.1 1.8 1 0 0 1 1 1 0 Complex1_LYR-like Vasculin PF15337.6 RKP02689.1 - 0.12 13.2 0.1 0.25 12.2 0.1 1.5 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 MTBP_C PF14920.6 RKP02689.1 - 8.6 6.0 16.8 42 3.8 7.6 3.6 3 0 0 3 3 3 0 MDM2-binding CHASE3 PF05227.13 RKP02689.1 - 8.6 6.3 15.2 6.1 6.8 0.4 2.5 2 0 0 2 2 2 0 CHASE3 domain Enolase_C PF00113.22 RKP02690.1 - 1.1e-154 514.0 0.1 1.4e-154 513.7 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 RKP02690.1 - 2.6e-56 189.4 0.1 4.2e-56 188.7 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 RKP02690.1 - 1.1e-07 31.7 0.0 2.7e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 RKP02690.1 - 0.012 14.7 0.1 0.026 13.7 0.1 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus GATA PF00320.27 RKP02691.1 - 3.2e-09 36.3 2.4 6e-09 35.4 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-CCCH_4 PF18044.1 RKP02691.1 - 0.00017 21.3 3.8 0.00032 20.4 3.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 RKP02691.1 - 0.0066 16.5 5.1 0.012 15.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RKP02691.1 - 0.022 14.7 2.2 0.045 13.7 2.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RKP02691.1 - 0.24 12.1 0.1 0.24 12.1 0.1 1.8 2 0 0 2 2 2 0 Torus domain SARAF PF06682.12 RKP02692.1 - 2.6e-26 93.1 0.0 5e-13 49.4 0.0 3.1 3 0 0 3 3 3 3 SOCE-associated regulatory factor of calcium homoeostasis NOC3p PF07540.11 RKP02694.1 - 7.3e-22 77.6 0.7 2.7e-21 75.8 0.0 2.4 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 RKP02694.1 - 2.8e-21 76.3 0.4 1.9e-20 73.6 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family LPD30 PF18850.1 RKP02694.1 - 0.021 14.6 0.7 0.044 13.5 0.3 1.7 1 1 1 2 2 2 0 Large polyvalent protein associated domain 30 RIX1 PF08167.12 RKP02694.1 - 0.059 13.1 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Phage_Gp23 PF10669.9 RKP02694.1 - 1.8 8.9 6.4 1.6 9.0 4.3 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) GTP_cyclohydroI PF01227.22 RKP02696.1 - 1.1e-72 243.2 0.1 1.3e-72 242.9 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 RKP02696.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein Tubulin-binding PF00418.19 RKP02697.1 - 6.4e-37 125.2 9.8 1.9e-10 40.5 0.1 4.2 4 0 0 4 4 4 4 Tau and MAP protein, tubulin-binding repeat Pneumo_att_G PF05539.11 RKP02697.1 - 0.28 10.8 7.3 0.39 10.3 7.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G C2 PF00168.30 RKP02698.1 - 3.1e-37 127.0 0.0 1.7e-16 60.3 0.0 3.5 3 0 0 3 3 3 3 C2 domain SMP_LBD PF17047.5 RKP02698.1 - 0.0066 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DUF2383 PF09537.10 RKP02698.1 - 0.17 12.3 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Ric8 PF10165.9 RKP02699.1 - 5.4e-74 249.9 0.0 3.2e-73 247.4 0.0 1.8 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn XAP5 PF04921.14 RKP02699.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator PITH PF06201.13 RKP02700.1 - 9e-30 103.9 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sel1 PF08238.12 RKP02701.1 - 2.2e-33 113.9 26.9 4.2e-08 33.6 0.1 6.2 6 0 0 6 6 6 6 Sel1 repeat Ufd2P_core PF10408.9 RKP02703.1 - 2.3e-170 568.3 0.0 2.9e-170 568.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 RKP02703.1 - 1.2e-24 86.2 0.5 3.2e-24 84.9 0.5 1.8 1 0 0 1 1 1 1 U-box domain Abhydrolase_9_N PF15420.6 RKP02703.1 - 2.8 7.9 8.6 13 5.7 0.7 2.4 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus PAS PF00989.25 RKP02704.1 - 7.5e-05 22.7 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 RKP02704.1 - 0.00017 21.7 7.1 0.00034 20.7 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MLTR_LBD PF17765.1 RKP02704.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain PAS_8 PF13188.7 RKP02704.1 - 0.074 13.1 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 PAS domain DUF1126 PF06565.12 RKP02706.1 - 3e-86 284.1 0.0 2.6e-31 107.5 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain E1_dh PF00676.20 RKP02707.1 - 2.6e-108 361.5 0.1 3.2e-108 361.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RKP02707.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Asp PF00026.23 RKP02708.1 - 2.6e-66 224.2 0.1 2.9e-66 224.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKP02708.1 - 1.1e-13 51.9 0.3 5.4e-11 43.0 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RKP02708.1 - 8.6e-07 28.9 0.1 2.5e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RasGEF PF00617.19 RKP02709.1 - 3.5e-55 186.9 0.0 6.1e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RKP02709.1 - 2.2e-21 76.1 0.0 4.7e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF2000 PF09391.10 RKP02709.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Stevor PF17410.2 RKP02710.1 - 0.0079 15.8 0.0 0.0079 15.8 0.0 2.2 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame TPR_2 PF07719.17 RKP02711.1 - 1.1e-10 40.8 6.9 0.00062 19.7 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 RKP02711.1 - 6.6e-10 39.1 7.7 2e-05 24.8 4.7 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02711.1 - 9.1e-10 37.9 2.5 0.0009 19.0 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKP02711.1 - 1.7e-07 30.9 0.0 0.092 13.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKP02711.1 - 2.2e-07 31.3 3.9 0.0003 21.2 0.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKP02711.1 - 5.9e-07 30.0 13.2 0.0001 22.9 0.6 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP02711.1 - 3.6e-06 27.1 1.0 0.0015 18.8 0.7 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKP02711.1 - 6.1e-06 26.6 8.9 0.58 11.1 0.2 4.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKP02711.1 - 3.2e-05 23.5 0.2 0.66 9.7 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 RKP02711.1 - 5.4e-05 22.9 1.3 3.4 7.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKP02711.1 - 0.00022 21.7 2.7 0.16 12.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKP02711.1 - 0.00024 20.4 0.9 0.0039 16.4 0.7 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKP02711.1 - 0.00063 19.8 1.3 0.00063 19.8 1.3 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 RKP02711.1 - 0.0068 16.7 0.6 0.58 10.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RKP02711.1 - 0.011 15.1 2.6 0.059 12.7 0.3 2.3 1 1 1 2 2 2 0 MalT-like TPR region RPN7 PF10602.9 RKP02711.1 - 0.023 14.4 0.0 2.4 7.9 0.0 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Phage_min_cap2 PF06152.11 RKP02711.1 - 0.19 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 TPR_20 PF14561.6 RKP02711.1 - 0.87 10.0 7.2 0.87 10.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 RKP02711.1 - 0.88 10.0 11.8 0.086 13.3 4.2 2.7 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 RKP02711.1 - 2.7 8.0 11.5 2.2 8.3 0.9 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_26 PF02156.15 RKP02712.1 - 8.2e-06 25.5 0.4 0.0076 15.7 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 RKP02712.1 - 0.1 12.1 0.7 0.2 11.2 0.7 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 RKP02712.1 - 0.15 11.7 0.3 0.31 10.7 0.3 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 RKP02712.1 - 0.22 11.5 1.1 0.52 10.4 1.1 1.7 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 RKP02713.1 - 9.1e-67 225.2 0.0 2.5e-62 210.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02713.1 - 3.2e-35 121.7 0.0 1e-32 113.4 0.0 2.0 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RKP02713.1 - 5.4e-05 23.2 0.4 0.0029 17.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RKP02713.1 - 0.0039 16.6 0.4 0.0054 16.1 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP02713.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RKP02713.1 - 0.019 13.9 0.3 0.027 13.4 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 RKP02713.1 - 0.036 13.6 0.3 0.067 12.8 0.3 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase K_channel_TID PF07941.11 RKP02713.1 - 0.14 12.6 6.5 0.23 11.9 6.5 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RIO1 PF01163.22 RKP02713.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Tim17 PF02466.19 RKP02714.1 - 2.9e-15 56.6 3.7 5.9e-15 55.6 3.7 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family XFP_N PF09364.10 RKP02715.1 - 3.7e-50 170.8 0.0 2.2e-46 158.4 0.0 3.0 2 1 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.10 RKP02715.1 - 1.6e-41 142.0 0.0 3.3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 RKP02715.1 - 5.1e-06 26.3 0.0 0.002 17.9 0.0 2.9 1 1 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase DHR-2 PF06920.13 RKP02715.1 - 0.13 10.9 0.2 0.2 10.3 0.2 1.1 1 0 0 1 1 1 0 Dock homology region 2 Spt20 PF12090.8 RKP02715.1 - 5.9 6.4 7.5 9.4 5.8 7.5 1.2 1 0 0 1 1 1 0 Spt20 family PNP_UDP_1 PF01048.20 RKP02716.1 - 1.3e-19 70.4 5.3 2.3e-19 69.6 5.3 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF2040 PF09745.9 RKP02717.1 - 5.5e-28 97.5 2.4 1.4e-27 96.1 2.4 1.7 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Connexin40_C PF16791.5 RKP02717.1 - 0.039 15.2 0.0 0.12 13.7 0.0 1.9 2 0 0 2 2 2 0 Connexin 40 C-terminal domain SARAF PF06682.12 RKP02717.1 - 1.1 8.9 4.2 1.2 8.7 0.3 2.4 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Sec1 PF00995.23 RKP02718.1 - 6e-124 415.4 0.0 7.3e-124 415.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family NAD_kinase PF01513.21 RKP02719.1 - 4.8e-58 196.7 0.0 6.3e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RKP02719.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain WD40 PF00400.32 RKP02721.1 - 5.9e-41 137.7 25.5 1.8e-06 28.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02721.1 - 2.3e-07 31.0 1.8 0.66 10.3 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP02721.1 - 1.5e-06 27.2 10.8 0.16 10.5 0.2 5.8 4 2 1 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RKP02721.1 - 2.6e-06 27.0 0.0 0.0035 16.7 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain DUF5046 PF16465.5 RKP02721.1 - 6e-05 22.6 0.1 0.29 10.5 0.0 3.1 1 1 1 3 3 3 1 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 RKP02721.1 - 0.0072 15.3 2.2 7.4 5.4 0.0 3.9 2 2 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 RKP02721.1 - 0.017 14.7 2.0 0.75 9.3 0.1 3.0 1 1 2 3 3 3 0 PQQ-like domain PQQ PF01011.21 RKP02721.1 - 0.03 14.2 0.0 28 4.9 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Ras PF00071.22 RKP02722.1 - 0.0093 15.6 0.0 0.078 12.6 0.0 2.0 2 0 0 2 2 2 1 Ras family DLEU7 PF15760.5 RKP02722.1 - 5.1 6.5 6.1 10 5.5 6.1 1.5 1 0 0 1 1 1 0 Leukemia-associated protein 7 Elong_Iki1 PF10483.9 RKP02723.1 - 1.3e-14 54.4 0.0 8.8e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Elongator subunit Iki1 PPI_Ypi1 PF07491.11 RKP02724.1 - 2.5e-21 75.3 4.8 7.2e-21 73.8 4.8 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.9 RKP02724.1 - 0.00057 19.6 6.5 0.00076 19.2 6.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4739 PF15893.5 RKP02724.1 - 0.0034 17.0 0.5 0.0046 16.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4739) AF-4 PF05110.13 RKP02724.1 - 0.021 13.0 4.1 0.023 12.8 4.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PGA2 PF07543.12 RKP02724.1 - 0.3 11.0 2.9 0.48 10.4 2.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 CCDC106 PF15794.5 RKP02724.1 - 2.3 7.9 6.1 3 7.5 6.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Herpes_DNAp_acc PF04929.12 RKP02724.1 - 3.7 6.4 4.8 4.6 6.1 4.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor adh_short PF00106.25 RKP02725.1 - 6e-78 260.8 17.2 1.1e-40 139.2 4.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 RKP02725.1 - 5.5e-62 209.4 18.1 3e-33 115.3 5.9 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 RKP02725.1 - 1.4e-32 111.9 0.0 3.4e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 RKP02725.1 - 3.7e-32 111.7 14.2 2.1e-16 60.3 3.0 2.2 2 0 0 2 2 2 2 KR domain SCP2 PF02036.17 RKP02725.1 - 6.7e-21 74.7 0.1 1.4e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family MaoC_dehydrat_N PF13452.6 RKP02725.1 - 1.4e-05 25.2 0.0 0.00031 20.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 RKP02725.1 - 0.0011 18.3 6.2 0.2 11.0 0.7 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Alkyl_sulf_C PF14864.6 RKP02725.1 - 0.0016 18.7 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal PglL_A PF15864.5 RKP02725.1 - 0.19 11.5 5.9 5.7 6.8 0.3 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase Pkinase PF00069.25 RKP02726.1 - 2.2e-47 161.6 0.0 2.5e-33 115.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02726.1 - 2e-20 73.2 0.0 2e-19 69.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP02726.1 - 8.8e-06 25.2 0.3 1.8e-05 24.2 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP02726.1 - 0.0034 17.3 0.7 0.0058 16.6 0.7 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP02726.1 - 0.005 16.2 0.1 0.0085 15.4 0.1 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RKP02726.1 - 0.028 14.0 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RKP02726.1 - 0.042 12.6 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 RKP02726.1 - 0.18 10.7 0.1 0.65 8.9 0.2 1.7 2 0 0 2 2 2 0 Haspin like kinase domain zf-MIZ PF02891.20 RKP02726.1 - 0.22 11.3 0.4 0.44 10.3 0.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Adaptin_N PF01602.20 RKP02728.1 - 1.5e-75 254.7 0.2 1.9e-75 254.5 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKP02728.1 - 4.9e-11 42.9 2.5 3.5e-08 33.6 0.1 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP02728.1 - 2.5e-06 27.8 10.9 0.0025 18.2 0.0 5.1 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 RKP02728.1 - 0.00011 22.2 10.8 0.3 11.5 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat TAF6_C PF07571.13 RKP02728.1 - 0.01 16.1 0.9 0.61 10.4 0.0 3.4 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain Cohesin_HEAT PF12765.7 RKP02728.1 - 0.035 14.4 0.7 1.2 9.5 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Proteasom_PSMB PF10508.9 RKP02728.1 - 0.056 11.9 1.7 1 7.8 0.3 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 RKP02728.1 - 0.081 13.5 6.9 0.37 11.3 0.3 4.4 5 0 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 RKP02728.1 - 0.53 10.4 2.5 64 3.8 0.0 4.7 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat LRR_4 PF12799.7 RKP02729.1 - 1.7e-15 56.8 5.3 1.9e-07 31.3 1.1 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP02729.1 - 1.4e-11 43.9 26.9 1.5e-06 27.8 3.7 4.1 2 2 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 RKP02729.1 - 2.9e-05 23.6 0.0 0.0061 16.1 0.1 2.5 2 0 0 2 2 2 2 Leucine-rich repeat MAD PF05557.13 RKP02730.1 - 0.033 12.6 25.5 0.046 12.1 25.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ATG16 PF08614.11 RKP02730.1 - 7.4 6.8 39.7 26 5.0 7.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RGS PF00615.19 RKP02733.1 - 0.00058 20.1 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain 7tm_3 PF00003.22 RKP02733.1 - 0.0072 16.1 3.8 0.0072 16.1 3.8 2.3 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Ribosomal_L5_C PF00673.21 RKP02735.1 - 5.7e-18 64.9 0.0 9.6e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus LCAT PF02450.15 RKP02736.1 - 9.6e-69 232.4 0.0 1.4e-68 231.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 RKP02736.1 - 0.23 12.1 8.1 0.53 10.9 7.3 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family CN_hydrolase PF00795.22 RKP02737.1 - 6.3e-17 61.8 0.1 8.1e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Synaptobrevin PF00957.21 RKP02738.1 - 7.3e-20 70.6 0.6 7.6e-20 70.5 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF3913 PF13052.6 RKP02738.1 - 0.044 14.0 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) RL10P_insert PF17777.1 RKP02739.1 - 1.9e-20 72.6 0.0 4.2e-20 71.5 0.0 1.5 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RKP02739.1 - 6.4e-18 64.7 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Nucleo_P87 PF07267.11 RKP02740.1 - 0.21 10.4 5.2 0.27 10.1 5.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.12 RKP02740.1 - 2.5 6.6 16.1 0.013 14.2 6.1 1.8 1 1 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 RKP02741.1 - 5.9e-80 269.0 11.3 9.4e-41 139.9 5.2 2.0 1 1 1 2 2 2 2 Presenilin SPP PF06550.11 RKP02741.1 - 0.00032 20.3 0.1 0.00032 20.3 0.1 2.1 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Peptidase_A22B PF04258.13 RKP02741.1 - 0.14 11.6 12.8 0.71 9.3 2.6 2.7 2 1 0 2 2 2 0 Signal peptide peptidase Arm PF00514.23 RKP02742.1 - 1.1e-09 38.0 3.5 0.0059 16.6 0.1 4.0 3 1 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 RKP02742.1 - 6.1e-07 29.8 10.5 0.00018 21.9 0.4 4.3 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 RKP02742.1 - 1.2e-06 28.8 5.7 1.2e-06 28.8 5.7 4.0 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.22 RKP02742.1 - 6.2e-05 22.9 11.1 0.093 13.0 0.1 5.5 6 1 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 RKP02742.1 - 0.0071 16.4 0.8 0.039 14.0 0.6 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKP02742.1 - 0.025 13.2 4.1 0.21 10.1 4.1 2.3 1 1 0 1 1 1 0 Adaptin N terminal region DUF383 PF04063.14 RKP02742.1 - 0.19 11.4 0.5 1.6 8.3 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF383) DUF3636 PF12331.8 RKP02742.1 - 3.3 7.5 6.8 7.4 6.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3636) HEAT_PBS PF03130.16 RKP02742.1 - 9.5 7.2 8.4 59 4.8 0.7 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat PDZ_1 PF12812.7 RKP02743.1 - 1.1e-44 150.3 0.0 1.6e-31 108.1 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 RKP02743.1 - 9.4e-19 68.8 0.0 7.2e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 RKP02743.1 - 1.2e-11 44.7 0.3 6.8e-05 23.1 0.0 4.0 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 RKP02743.1 - 1.1e-08 34.8 0.2 0.00016 21.4 0.1 4.4 5 0 0 5 5 5 2 PDZ domain PDZ PF00595.24 RKP02743.1 - 2.1e-08 34.4 0.0 0.00017 21.9 0.1 3.6 3 0 0 3 3 3 2 PDZ domain Hydrolase_4 PF12146.8 RKP02744.1 - 5.4e-57 192.8 0.3 6.1e-57 192.6 0.3 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKP02744.1 - 7.5e-21 74.9 0.3 7.5e-16 58.5 0.3 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RKP02744.1 - 2.5e-12 47.9 5.2 3.2e-12 47.6 5.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RKP02744.1 - 1.1e-05 25.0 0.1 0.077 12.5 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RKP02744.1 - 2.1e-05 24.3 0.1 3.1e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 RKP02744.1 - 0.00038 19.2 0.9 0.042 12.5 0.9 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 RKP02744.1 - 0.0038 17.4 0.2 0.0051 16.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 RKP02744.1 - 0.019 14.6 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 RKP02744.1 - 0.025 14.4 0.1 2.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 RKP02744.1 - 0.037 12.8 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DLH PF01738.18 RKP02744.1 - 0.16 11.5 0.0 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 RKP02744.1 - 0.28 10.6 3.7 1.1 8.7 1.7 2.1 1 1 0 2 2 2 0 Esterase PHB depolymerase Peptidase_C97 PF05903.14 RKP02745.1 - 8.6e-35 119.8 0.0 9.5e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 RKP02745.1 - 0.0083 16.4 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DnaJ PF00226.31 RKP02746.1 - 3.5e-13 49.5 0.2 6.1e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain tRNA_int_endo PF01974.17 RKP02747.1 - 9e-16 57.7 0.1 1.8e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SR-25 PF10500.9 RKP02748.1 - 0.076 12.6 10.6 0.12 11.9 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 RKP02748.1 - 0.52 11.0 7.2 1.3 9.8 7.2 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Sld5 PF05916.11 RKP02749.1 - 0.015 15.8 0.0 0.038 14.5 0.0 1.7 2 0 0 2 2 2 0 GINS complex protein Acyl-CoA_dh_N PF02771.16 RKP02750.1 - 2.2e-28 99.2 0.1 5.2e-28 98.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 RKP02750.1 - 1e-27 97.2 0.6 2.4e-27 96.0 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKP02750.1 - 1.8e-20 72.9 0.0 3.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKP02750.1 - 9.6e-06 25.9 0.7 9.6e-06 25.9 0.7 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cation_efflux PF01545.21 RKP02751.1 - 1.3e-42 145.8 13.5 7.9e-42 143.2 13.5 1.9 1 1 0 1 1 1 1 Cation efflux family CKS PF01111.19 RKP02752.1 - 3.2e-33 113.8 0.2 4e-33 113.5 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit INSC_LBD PF16748.5 RKP02752.1 - 0.0045 16.4 0.1 0.0072 15.8 0.1 1.3 1 0 0 1 1 1 1 Inscuteable LGN-binding domain Apt1 PF10351.9 RKP02753.1 - 4.7e-83 279.7 0.3 8.2e-63 212.9 0.0 3.5 4 0 0 4 4 4 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 RKP02753.1 - 1.5e-30 106.4 0.0 3.4e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_WPPW PF10359.9 RKP02753.1 - 2e-19 69.9 0.0 4.3e-18 65.4 0.0 2.6 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 RKP02753.1 - 2.4e-18 66.6 0.0 7.5e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) ATP-synt_10 PF05176.14 RKP02754.1 - 9.5e-34 116.8 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein ATG13 PF10033.9 RKP02755.1 - 5.8e-32 111.3 0.0 1.1e-31 110.4 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 Ribosomal_L34 PF00468.17 RKP02756.1 - 8.6e-18 64.0 4.8 9.6e-18 63.9 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 Methyltransf_2 PF00891.18 RKP02757.1 - 1.3e-27 96.5 0.0 1.8e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 RKP02757.1 - 1.8e-09 37.4 0.1 7.9e-09 35.4 0.1 2.0 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_25 PF13649.6 RKP02757.1 - 0.0075 17.0 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.25 RKP02758.1 - 2.3e-74 250.1 0.0 2.6e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02758.1 - 1.7e-46 158.6 0.0 1.9e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP02758.1 - 7.2e-08 31.6 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 RKP02758.1 - 7.1e-06 25.7 0.1 0.00011 21.8 0.0 2.2 2 1 1 3 3 3 1 RIO1 family Kinase-like PF14531.6 RKP02758.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP02758.1 - 0.0024 17.8 0.3 0.017 15.0 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP02758.1 - 0.028 13.4 0.4 0.036 13.0 0.4 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 RKP02758.1 - 0.071 12.4 0.0 0.071 12.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP-Tp47_a PF14889.6 RKP02758.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a UCH PF00443.29 RKP02759.1 - 8.8e-38 130.3 0.0 5.5e-37 127.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 RKP02759.1 - 1.6e-27 95.6 16.5 8.1e-21 74.1 3.6 2.9 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 RKP02759.1 - 5.7e-26 90.1 1.5 3.2e-24 84.5 0.2 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 RKP02759.1 - 9.5e-20 70.1 2.0 1.2e-09 37.8 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 RKP02759.1 - 1.3e-12 48.0 0.0 2.8e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Phage_holin_2_4 PF16082.5 RKP02760.1 - 0.0087 15.8 2.8 1 9.1 0.3 3.1 2 0 0 2 2 2 2 Bacteriophage holin family, superfamily II-like SH3_9 PF14604.6 RKP02760.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 RKP02760.1 - 0.044 13.4 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 RKP02760.1 - 0.045 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain HMG_box PF00505.19 RKP02761.1 - 2.8e-12 46.9 0.1 3.1e-12 46.7 0.1 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box CHDNT PF08073.12 RKP02761.1 - 0.003 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain MATalpha_HMGbox PF04769.12 RKP02761.1 - 0.034 13.5 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box zf-CCHC PF00098.23 RKP02762.1 - 5e-05 23.2 4.1 8.1e-05 22.5 4.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RKP02762.1 - 0.045 13.6 4.6 0.069 13.0 4.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 RKP02762.1 - 0.095 12.4 4.2 0.19 11.5 4.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 RKP02762.1 - 0.19 12.1 1.4 0.23 11.9 1.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Gelsolin PF00626.22 RKP02763.1 - 2e-16 59.7 0.0 1.4e-06 28.1 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat VHP PF02209.19 RKP02763.1 - 6.1e-05 23.0 0.2 0.00011 22.2 0.2 1.4 1 0 0 1 1 1 1 Villin headpiece domain FAA_hydrolase PF01557.18 RKP02765.1 - 5.6e-51 173.3 0.0 7.9e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 RKP02765.1 - 6.8e-19 68.0 0.0 1.5e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal UDG PF03167.19 RKP02766.1 - 1e-14 54.8 0.8 2.5e-14 53.6 0.0 2.0 3 0 0 3 3 3 1 Uracil DNA glycosylase superfamily DUF3080 PF11279.8 RKP02767.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Nuc_sug_transp PF04142.15 RKP02768.1 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 RKP02768.1 - 0.44 10.7 24.6 0.91 9.7 6.2 3.2 2 1 0 2 2 2 0 EamA-like transporter family DUF1752 PF08550.10 RKP02769.1 - 6.4e-09 35.5 0.2 1.3e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CENP-C_C PF11699.8 RKP02770.1 - 9.5e-26 89.8 0.1 1.4e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 RKP02770.1 - 4.3e-05 23.1 0.0 7.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DMSP_lyase PF16867.5 RKP02770.1 - 0.12 12.1 0.4 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase YL1_C PF08265.11 RKP02771.1 - 1.5e-12 47.0 4.1 2.8e-12 46.1 4.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain TFIID_20kDa PF03847.13 RKP02772.1 - 1.1e-11 45.1 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A EamA PF00892.20 RKP02773.1 - 2.5e-12 47.1 22.7 1e-06 29.0 11.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 RKP02773.1 - 3.7e-07 29.6 0.1 6.7e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 RKP02773.1 - 6.9e-06 25.6 3.7 0.02 14.2 0.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 RKP02773.1 - 8.1e-05 21.9 0.0 9.9e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 RKP02773.1 - 0.0027 16.7 1.9 0.043 12.8 0.3 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TMEMspv1-c74-12 PF11044.8 RKP02773.1 - 2 8.5 3.6 0.91 9.6 0.2 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein EF-hand_7 PF13499.6 RKP02774.1 - 7e-08 32.8 0.4 9.2e-08 32.4 0.4 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RKP02774.1 - 6.2e-06 25.5 4.0 0.0019 17.6 0.4 2.6 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 RKP02774.1 - 2.6e-05 23.4 4.4 0.0081 15.6 0.1 2.6 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 RKP02774.1 - 4.4e-05 23.1 3.9 0.06 13.3 1.2 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 RKP02774.1 - 0.0014 18.5 1.3 0.0017 18.2 0.0 1.9 2 1 0 2 2 2 1 EF-hand domain pair DUF2729 PF10870.8 RKP02774.1 - 0.055 13.3 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) zf-AN1 PF01428.16 RKP02775.1 - 2.9e-19 68.9 24.7 6.3e-10 39.1 7.2 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 RKP02775.1 - 0.0098 16.2 11.7 0.029 14.7 0.6 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.21 RKP02775.1 - 0.88 9.8 21.1 1.4 9.2 7.3 2.9 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_L35p PF01632.19 RKP02776.1 - 2.8e-09 37.4 5.8 4.6e-09 36.7 5.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 AAA_6 PF12774.7 RKP02777.1 - 3.1e-133 443.8 0.1 2.4e-104 348.9 0.0 3.8 4 0 0 4 4 4 3 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RKP02777.1 - 1.1e-108 364.4 1.4 1.1e-108 364.4 1.4 2.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RKP02777.1 - 2.4e-108 362.8 0.5 2.4e-108 362.8 0.5 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 RKP02777.1 - 3.6e-70 235.5 5.3 5.1e-70 235.0 0.0 3.4 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 RKP02777.1 - 1.2e-65 221.4 0.0 4.1e-65 219.7 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 RKP02777.1 - 6.1e-45 153.7 3.2 1.2e-44 152.8 3.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 RKP02777.1 - 2.3e-43 147.8 0.0 1.7e-36 125.4 0.0 5.0 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 RKP02777.1 - 3e-38 130.9 0.0 1.9e-14 53.8 0.0 6.3 7 1 0 7 7 4 4 AAA domain (dynein-related subfamily) Dynein_C PF18199.1 RKP02777.1 - 1.3e-34 119.9 0.0 4.6e-34 118.0 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 RKP02777.1 - 1e-28 100.2 0.0 2.3e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKP02777.1 - 3.7e-22 78.7 0.0 3.7e-21 75.4 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 RKP02777.1 - 1.6e-15 57.6 2.0 0.00097 19.4 0.0 6.2 6 0 0 6 6 5 2 AAA domain AAA PF00004.29 RKP02777.1 - 7.4e-15 55.5 0.0 0.00056 20.3 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 RKP02777.1 - 2.6e-09 37.3 0.0 7.6e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RKP02777.1 - 4.5e-09 36.9 16.5 0.12 12.8 0.1 9.6 8 2 0 10 10 6 2 AAA ATPase domain AAA_18 PF13238.6 RKP02777.1 - 1.6e-08 35.2 0.0 0.65 10.5 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 RKP02777.1 - 1.4e-07 31.8 12.1 0.11 12.6 0.0 7.5 7 1 0 8 8 6 3 AAA domain T2SSE PF00437.20 RKP02777.1 - 6.6e-06 25.4 0.0 0.005 15.9 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 RKP02777.1 - 8e-06 26.0 0.0 6.6e-05 23.1 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain Rad17 PF03215.15 RKP02777.1 - 9.5e-06 25.7 0.1 0.36 10.7 0.0 4.0 4 0 0 4 4 4 1 Rad17 P-loop domain IstB_IS21 PF01695.17 RKP02777.1 - 3.1e-05 23.8 0.2 0.32 10.7 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 RKP02777.1 - 4e-05 24.0 0.6 0.4 11.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 RKP02777.1 - 6.6e-05 23.0 0.0 0.95 9.5 0.0 4.3 5 0 0 5 5 3 1 AAA domain AAA_29 PF13555.6 RKP02777.1 - 0.00013 21.7 0.2 1.1 9.1 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 RKP02777.1 - 0.00017 21.9 0.0 1.5 9.2 0.0 4.5 4 0 0 4 4 4 1 RNA helicase BRE1 PF08647.11 RKP02777.1 - 0.00022 21.2 1.1 0.00022 21.2 1.1 4.2 4 1 0 5 5 3 1 BRE1 E3 ubiquitin ligase ABC_tran PF00005.27 RKP02777.1 - 0.0003 21.3 3.0 1.5 9.4 0.1 4.3 4 0 0 4 4 3 1 ABC transporter FtsK_SpoIIIE PF01580.18 RKP02777.1 - 0.00039 19.9 0.0 1 8.6 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_28 PF13521.6 RKP02777.1 - 0.00067 19.9 0.0 17 5.6 0.0 5.0 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 RKP02777.1 - 0.0007 19.0 3.7 2.6 7.4 0.0 3.9 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 RKP02777.1 - 0.0008 19.4 0.0 2.9 7.8 0.0 3.8 3 0 0 3 3 3 1 RsgA GTPase PspA_IM30 PF04012.12 RKP02777.1 - 0.00092 18.8 2.7 0.00092 18.8 2.7 4.4 4 0 0 4 4 2 1 PspA/IM30 family AAA_24 PF13479.6 RKP02777.1 - 0.003 17.3 0.4 61 3.2 0.0 4.6 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 RKP02777.1 - 0.0062 16.5 0.9 7.2 6.6 0.0 4.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 RKP02777.1 - 0.027 14.2 0.1 1.2 8.8 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Guanylate_kin PF00625.21 RKP02777.1 - 0.029 14.1 0.0 9.9 5.8 0.0 3.0 2 0 0 2 2 2 0 Guanylate kinase AAA_25 PF13481.6 RKP02777.1 - 0.034 13.7 9.6 0.1 12.1 0.0 5.3 5 0 0 5 5 5 0 AAA domain NACHT PF05729.12 RKP02777.1 - 0.076 12.9 2.5 45 3.9 0.1 4.5 4 0 0 4 4 3 0 NACHT domain DUF1664 PF07889.12 RKP02777.1 - 0.2 11.7 16.0 2.4 8.2 0.2 5.9 5 1 1 6 6 5 0 Protein of unknown function (DUF1664) XhlA PF10779.9 RKP02777.1 - 3.2 8.0 4.2 6 7.2 0.4 3.4 3 0 0 3 3 2 0 Haemolysin XhlA AAA_11 PF13086.6 RKP02777.1 - 6.7 6.4 8.8 2.9 7.6 0.0 4.4 5 0 0 5 5 4 0 AAA domain AAA_23 PF13476.6 RKP02777.1 - 7.9 6.9 9.2 20 5.6 0.0 5.0 5 0 0 5 5 4 0 AAA domain MbeB_N PF04837.12 RKP02777.1 - 9.5 6.6 8.1 4.3 7.7 0.1 4.1 4 0 0 4 4 3 0 MbeB-like, N-term conserved region E1-E2_ATPase PF00122.20 RKP02778.1 - 5.6e-19 68.4 0.3 2.7e-18 66.2 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RKP02778.1 - 3.4e-13 50.4 2.7 7.2e-05 23.2 0.0 3.9 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP02778.1 - 0.0007 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) NADPH_Ox PF08414.10 RKP02778.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase S6PP PF05116.13 RKP02778.1 - 0.15 11.6 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 RKP02778.1 - 0.16 11.7 0.2 0.35 10.6 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3970 PF13113.6 RKP02778.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) AMMECR1 PF01871.17 RKP02779.1 - 8.6e-45 152.3 0.0 9.9e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Cnn_1N PF07989.11 RKP02780.1 - 5.2e-11 42.5 1.6 5.2e-11 42.5 1.6 14.0 9 5 4 14 14 14 3 Centrosomin N-terminal motif 1 YabA PF06156.13 RKP02780.1 - 0.012 16.2 2.8 0.012 16.2 2.8 13.6 6 4 8 14 14 14 0 Initiation control protein YabA Snf7 PF03357.21 RKP02781.1 - 1.2e-32 112.9 11.5 1.4e-32 112.7 11.5 1.0 1 0 0 1 1 1 1 Snf7 AAA PF00004.29 RKP02782.1 - 6.4e-32 110.8 0.0 1.8e-31 109.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKP02782.1 - 9.2e-09 35.0 1.5 1.5e-08 34.3 0.4 1.9 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 RKP02782.1 - 2.1e-06 27.6 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKP02782.1 - 0.00011 22.5 0.2 0.011 16.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 RKP02782.1 - 0.0006 19.1 0.0 0.00089 18.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 RKP02782.1 - 0.00073 19.6 0.0 0.0026 17.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKP02782.1 - 0.0012 19.2 1.4 0.0065 16.9 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 RKP02782.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 RKP02782.1 - 0.0024 17.9 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP02782.1 - 0.0031 18.0 0.0 0.0067 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RKP02782.1 - 0.0039 16.9 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKP02782.1 - 0.0048 16.3 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKP02782.1 - 0.0098 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 RKP02782.1 - 0.018 14.4 0.1 0.55 9.5 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 RKP02782.1 - 0.021 15.2 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 RKP02782.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RKP02782.1 - 0.035 13.7 0.3 0.21 11.2 0.2 2.2 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 RKP02782.1 - 0.05 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 RKP02782.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 RKP02782.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 RKP02782.1 - 0.074 12.8 0.0 0.72 9.5 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.11 RKP02782.1 - 0.16 11.8 0.2 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 RKP02782.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 RKP02782.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UQ_con PF00179.26 RKP02783.1 - 5.8e-51 171.8 0.0 6.6e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKP02783.1 - 5e-05 23.0 0.0 6.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RKP02783.1 - 0.07 13.4 0.0 0.098 12.9 0.0 1.3 1 1 0 1 1 1 0 RWD domain Adeno_E3_14_5 PF04834.12 RKP02783.1 - 0.12 12.9 0.1 0.3 11.6 0.1 1.6 1 1 1 2 2 2 0 Early E3 14.5 kDa protein Kinesin PF00225.23 RKP02784.1 - 5.6e-92 308.2 0.0 6.1e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP02784.1 - 1.4e-24 86.8 0.0 2.4e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 RKP02784.1 - 0.19 10.9 0.4 0.34 10.0 0.4 1.3 1 0 0 1 1 1 0 PIF1-like helicase DnaJ-X PF14308.6 RKP02785.1 - 8.9e-46 156.0 0.1 1.1e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 RKP02785.1 - 4.9e-25 87.4 0.3 1e-24 86.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Lactamase_B_2 PF12706.7 RKP02786.1 - 2.4e-25 89.2 0.1 2.9e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 RKP02786.1 - 8.3e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily HECT PF00632.25 RKP02787.1 - 7.9e-52 176.7 0.0 8.9e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4618 PF15397.6 RKP02788.1 - 4.5 6.6 11.7 0.33 10.3 2.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Hydrophobin PF01185.18 RKP02789.1 - 1e-07 32.5 10.9 3.1e-07 30.9 6.0 3.3 2 1 0 2 2 2 1 Fungal hydrophobin zf-C2H2 PF00096.26 RKP02791.1 - 8.6e-06 25.9 6.4 0.0048 17.3 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02791.1 - 0.0047 17.6 6.6 0.51 11.3 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP02791.1 - 0.11 12.9 1.0 0.11 12.9 1.0 3.0 3 1 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 RKP02791.1 - 0.22 12.2 1.9 13 6.5 0.1 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain TPR_2 PF07719.17 RKP02792.1 - 0.006 16.6 0.1 11 6.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02792.1 - 0.027 14.3 0.0 61 3.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat 3-HAO PF06052.12 RKP02793.1 - 5.9e-65 217.5 0.0 7e-65 217.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Nudix_N_2 PF14803.6 RKP02793.1 - 0.002 18.0 1.9 0.98 9.4 0.1 2.5 2 0 0 2 2 2 2 Nudix N-terminal Cupin_2 PF07883.11 RKP02793.1 - 0.003 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 RKP02793.1 - 0.0038 17.2 1.2 0.0072 16.3 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 RKP02793.1 - 0.01 15.9 0.6 0.04 14.0 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RKP02793.1 - 0.034 14.1 1.8 7.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RanBP PF00641.18 RKP02793.1 - 0.035 13.4 3.3 0.63 9.4 0.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 RKP02793.1 - 0.095 12.1 2.8 5.9 6.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 RKP02793.1 - 0.27 10.9 3.3 0.24 11.0 0.9 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RRP7 PF12923.7 RKP02794.1 - 9.9e-17 61.2 0.0 2.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain PKcGMP_CC PF16808.5 RKP02797.1 - 0.021 14.7 9.6 0.2 11.5 0.0 5.1 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM72 PF14976.6 RKP02798.1 - 1.6e-45 154.8 2.7 1.8e-45 154.6 2.7 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 RKP02798.1 - 0.23 11.7 6.3 0.98 9.7 6.3 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Lebercilin PF15619.6 RKP02799.1 - 3.9e-09 36.5 7.1 6e-09 35.8 7.1 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 RKP02799.1 - 0.011 16.0 0.4 0.024 14.9 0.2 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 RKP02799.1 - 0.059 13.5 2.1 0.33 11.1 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 RKP02799.1 - 0.11 12.9 3.6 0.073 13.5 1.6 1.7 1 1 0 1 1 1 0 Cell division protein ZapB SOGA PF11365.8 RKP02799.1 - 1.2 10.3 5.9 2.6 9.2 3.2 2.6 2 1 0 2 2 2 0 Protein SOGA YabA PF06156.13 RKP02799.1 - 1.8 9.2 3.2 22 5.7 3.2 2.1 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 RKP02799.1 - 2.1 8.2 7.6 0.12 12.1 1.1 2.0 2 0 0 2 2 2 0 Septum formation initiator MBOAT PF03062.19 RKP02800.1 - 1.6e-26 93.5 2.5 6.4e-26 91.5 2.4 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family zf-C3HC4_2 PF13923.6 RKP02801.1 - 4.7e-08 32.8 13.7 4.7e-08 32.8 13.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP02801.1 - 5.8e-08 32.5 14.4 1.1e-07 31.6 14.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 RKP02801.1 - 6.2e-08 32.4 1.5 6.2e-08 32.4 1.5 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 RKP02801.1 - 8.6e-08 32.0 13.7 1.5e-07 31.3 13.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RKP02801.1 - 1.4e-07 31.2 9.1 2.4e-07 30.5 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP02801.1 - 2.4e-07 30.6 8.7 2.4e-07 30.6 8.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RKP02801.1 - 1.9e-06 28.1 13.0 4e-06 27.0 13.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 RKP02801.1 - 8.5e-06 25.8 10.8 3.3e-05 24.0 11.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 RKP02801.1 - 1.3e-05 25.1 3.0 2.8e-05 24.0 3.0 1.6 1 0 0 1 1 1 1 Zinc finger domain Prok-RING_4 PF14447.6 RKP02801.1 - 0.00026 20.8 10.0 0.00048 19.9 10.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 RKP02801.1 - 0.0039 17.4 10.0 0.03 14.6 10.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 RKP02801.1 - 0.0059 16.4 9.1 0.011 15.6 9.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_4 PF18044.1 RKP02801.1 - 0.0094 15.7 2.2 0.0094 15.7 2.2 1.9 2 0 0 2 2 1 1 CCCH-type zinc finger zf-RING_10 PF16685.5 RKP02801.1 - 0.024 14.7 7.0 0.024 14.7 7.0 1.6 2 0 0 2 2 1 0 zinc RING finger of MSL2 zf-CCCH_2 PF14608.6 RKP02801.1 - 0.037 14.5 3.0 0.13 12.8 3.0 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-RING_6 PF14835.6 RKP02801.1 - 0.037 13.9 7.3 0.079 12.8 7.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rtf2 PF04641.12 RKP02801.1 - 0.13 11.6 2.1 0.19 11.0 2.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Siva PF05458.12 RKP02801.1 - 0.2 11.3 6.3 0.28 10.9 6.3 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-P11 PF03854.14 RKP02801.1 - 0.23 11.2 9.1 0.93 9.2 9.1 1.9 1 1 0 1 1 1 0 P-11 zinc finger MOZ_SAS PF01853.18 RKP02802.1 - 1.4e-26 93.2 0.0 1.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RKP02802.1 - 4.3e-10 39.0 0.3 6.7e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 RKP02802.1 - 0.00036 20.9 0.0 0.00067 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKP02802.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family WD40 PF00400.32 RKP02803.1 - 3e-18 65.8 2.6 0.00018 22.2 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02803.1 - 4.9e-06 26.8 0.0 0.091 13.1 0.0 3.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP02803.1 - 0.00011 21.0 0.0 0.28 9.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKP02803.1 - 0.002 17.2 0.3 1.7 7.5 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 RKP02803.1 - 0.11 11.6 0.2 0.95 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) SPRY PF00622.28 RKP02804.1 - 6.4e-25 87.6 0.1 9.4e-25 87.1 0.1 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 RKP02804.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RKP02804.1 - 1.3 9.0 5.5 0.31 11.1 1.1 2.2 2 0 0 2 2 2 0 LisH cwf21 PF08312.12 RKP02805.1 - 2e-09 37.5 3.1 4e-09 36.5 3.1 1.5 1 0 0 1 1 1 1 cwf21 domain RNA_pol_3_Rpc31 PF11705.8 RKP02806.1 - 6.7e-18 65.8 0.5 1.1e-17 65.0 0.5 1.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 RKP02806.1 - 8.3 5.9 6.7 6.6 6.2 5.5 1.4 2 0 0 2 2 2 0 PPP4R2 zf-RING_2 PF13639.6 RKP02807.1 - 2.9e-11 43.5 7.5 5.2e-11 42.7 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RKP02807.1 - 2.5e-10 39.9 1.9 5.4e-10 38.8 1.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RKP02807.1 - 3.2e-07 30.1 6.0 5.8e-07 29.3 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP02807.1 - 4.9e-06 26.3 5.0 8.3e-06 25.6 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RKP02807.1 - 3.2e-05 24.1 4.7 8.3e-05 22.8 4.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 RKP02807.1 - 5.5e-05 23.1 1.2 0.00014 21.8 0.1 2.3 2 0 0 2 2 2 1 PA domain zf-RING_5 PF14634.6 RKP02807.1 - 7.3e-05 22.6 3.8 0.00013 21.9 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKP02807.1 - 0.0012 18.8 2.4 0.0019 18.2 0.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 RKP02807.1 - 0.049 13.7 3.5 0.1 12.6 3.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RKP02807.1 - 0.1 12.4 8.3 0.19 11.6 8.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKP02807.1 - 0.58 10.1 8.4 1.1 9.2 8.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 RKP02807.1 - 0.59 10.3 6.7 1.2 9.3 6.7 1.6 1 0 0 1 1 1 0 RING-variant domain HbrB PF08539.11 RKP02808.1 - 1.6e-29 103.1 0.0 7.8e-29 100.8 0.0 1.9 1 1 0 1 1 1 1 HbrB-like DUF896 PF05979.12 RKP02808.1 - 0.026 14.4 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Cyclin PF08613.11 RKP02809.1 - 2.3e-09 37.8 0.0 2.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin PF08613.11 RKP02810.1 - 2.2e-20 73.7 0.1 2.4e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 Cyclin zf-C2H2_aberr PF17017.5 RKP02811.1 - 0.25 11.5 0.0 0.38 10.9 0.0 1.1 1 0 0 1 1 1 0 Aberrant zinc-finger PNGaseA PF12222.8 RKP02812.1 - 1.8e-59 201.7 0.2 2.4e-32 112.3 0.0 2.3 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A TPR_2 PF07719.17 RKP02813.1 - 1.1e-18 65.8 6.6 0.00034 20.5 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 RKP02813.1 - 3.7e-12 46.0 9.4 0.19 12.6 0.0 7.7 4 1 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 RKP02813.1 - 1.8e-11 43.6 0.0 0.00096 19.4 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP02813.1 - 1.3e-10 40.6 0.6 0.018 14.9 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP02813.1 - 2.6e-09 36.6 0.3 0.11 12.8 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKP02813.1 - 4.2e-09 36.8 0.6 0.002 18.6 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKP02813.1 - 4.5e-08 33.6 7.8 0.017 15.8 0.7 5.8 6 1 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP02813.1 - 3.3e-07 30.4 0.5 0.059 13.6 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RKP02813.1 - 2.3e-06 27.2 0.0 0.24 11.1 0.0 4.0 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 RKP02813.1 - 6.2e-06 26.4 16.8 0.025 14.9 0.0 6.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKP02813.1 - 0.00035 20.4 11.1 0.0092 15.9 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKP02813.1 - 0.00063 19.1 3.6 0.00063 19.1 3.6 4.5 3 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKP02813.1 - 0.0034 17.9 5.8 18 6.2 0.0 6.3 7 1 0 7 7 5 0 Tetratricopeptide repeat RPN7 PF10602.9 RKP02813.1 - 0.0061 16.3 0.4 0.13 12.0 0.2 3.2 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 RKP02813.1 - 0.0085 16.2 9.4 0.16 12.1 3.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKP02813.1 - 0.1 12.7 0.4 37 4.5 0.0 3.8 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RKP02813.1 - 0.29 11.1 14.4 1.4 8.9 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.17 RKP02813.1 - 3.9 7.9 15.5 16 5.9 0.0 5.6 4 1 2 6 6 6 0 Bacterial transcriptional activator domain DFP PF04127.15 RKP02814.1 - 1.3e-19 70.8 0.0 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Glyco_hydro_cc PF11790.8 RKP02815.1 - 5.4e-60 202.9 1.4 7e-60 202.6 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SOG2 PF10428.9 RKP02815.1 - 5.1 6.2 20.6 6.9 5.7 20.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_4 PF12799.7 RKP02816.1 - 0.002 18.5 4.1 35 5.0 0.0 5.6 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RKP02816.1 - 0.015 15.3 12.6 0.26 11.5 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich repeat SAM_Ste50p PF09235.10 RKP02816.1 - 0.024 14.9 0.2 5.3 7.4 0.0 3.3 3 0 0 3 3 3 0 Ste50p, sterile alpha motif TF_Zn_Ribbon PF08271.12 RKP02816.1 - 0.1 12.1 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Nas2_N PF18265.1 RKP02817.1 - 0.014 15.3 0.5 0.014 15.3 0.5 5.9 5 3 2 7 7 7 0 Nas2 N_terminal domain MLD PF11647.8 RKP02817.1 - 4.2 7.7 6.9 12 6.3 1.0 3.8 3 0 0 3 3 3 0 Membrane Localization Domain Acatn PF13000.7 RKP02818.1 - 3.3e-160 534.2 16.3 1.1e-85 288.3 14.2 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 SSB PF00436.25 RKP02820.1 - 3e-06 27.2 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 RKP02820.1 - 0.063 13.3 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain COX5A PF02284.16 RKP02821.1 - 4.1e-26 91.0 0.1 4.9e-26 90.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Sel_put PF04328.13 RKP02821.1 - 0.01 15.8 0.3 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Selenoprotein, putative Ku_PK_bind PF08785.11 RKP02821.1 - 0.14 12.3 0.0 2.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Ku C terminal domain like Hydrophobin PF01185.18 RKP02823.1 - 8e-06 26.4 8.8 1.9e-05 25.2 8.8 1.6 1 1 1 2 2 2 2 Fungal hydrophobin DnaJ PF00226.31 RKP02824.1 - 4.9e-18 65.0 0.3 7.4e-18 64.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 RKP02824.1 - 0.016 15.5 0.1 0.022 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 RKP02824.1 - 0.16 12.0 7.7 0.28 11.2 7.7 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 RKP02824.1 - 0.3 11.4 2.1 0.49 10.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Asn_synthase PF00733.21 RKP02825.1 - 2.9e-90 303.5 2.0 1.7e-56 192.4 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 RKP02825.1 - 9.6e-38 128.9 0.0 1.7e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 RKP02825.1 - 8.1e-28 97.3 0.0 1.8e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 RKP02825.1 - 2.5e-07 30.4 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 RKP02825.1 - 0.048 12.8 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD synthase ABC_membrane PF00664.23 RKP02826.1 - 2.9e-55 187.9 11.3 3.8e-55 187.5 11.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKP02826.1 - 3.2e-30 105.4 0.0 1e-29 103.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RKP02826.1 - 0.00027 20.4 0.9 0.014 14.8 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 RKP02826.1 - 0.00048 19.5 0.0 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 RKP02826.1 - 0.0028 18.1 0.0 0.0083 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKP02826.1 - 0.03 14.6 0.0 0.17 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 RKP02826.1 - 0.042 13.6 0.0 0.098 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 RKP02826.1 - 0.061 13.1 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 RKP02826.1 - 0.062 13.2 0.6 0.18 11.7 0.0 2.1 3 0 0 3 3 3 0 Adenylylsulphate kinase NB-ARC PF00931.22 RKP02826.1 - 0.084 12.1 0.0 7.6 5.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 RKP02826.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 RKP02827.1 - 3.6e-32 111.7 0.0 6.8e-19 68.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 RKP02827.1 - 8.1e-08 31.9 0.0 0.0029 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RKP02827.1 - 5.4e-07 30.0 1.8 0.051 13.9 0.7 4.1 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 RKP02827.1 - 8e-07 29.6 16.1 0.0046 17.3 0.4 4.6 3 2 0 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.6 RKP02827.1 - 1.1e-06 28.7 1.0 1.5e-05 25.1 0.1 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 RKP02827.1 - 2.6e-05 24.8 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 RKP02827.1 - 8.5e-05 22.5 0.0 0.52 10.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RKP02827.1 - 0.00013 21.5 0.0 1 8.8 0.0 3.3 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 RKP02827.1 - 0.00021 21.0 0.2 0.2 11.3 0.1 3.4 3 1 0 3 3 3 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 RKP02827.1 - 0.00024 21.0 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 RKP02827.1 - 0.00026 21.3 0.2 2.7 8.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 RKP02827.1 - 0.00028 20.9 0.1 0.99 9.3 0.0 2.9 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 RKP02827.1 - 0.00062 18.9 0.7 0.12 11.4 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 RKP02827.1 - 0.0012 18.6 7.9 2.8 7.6 0.1 4.5 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 RKP02827.1 - 0.0016 18.2 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RKP02827.1 - 0.0019 18.4 7.2 0.18 12.0 0.0 3.6 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 RKP02827.1 - 0.0019 18.7 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 RKP02827.1 - 0.0023 17.9 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain cobW PF02492.19 RKP02827.1 - 0.0024 17.5 0.2 0.27 10.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 RKP02827.1 - 0.01 15.8 0.7 6 6.9 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 RKP02827.1 - 0.011 15.7 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 RKP02827.1 - 0.012 15.0 0.0 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RKP02827.1 - 0.03 14.3 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RKP02827.1 - 0.031 14.7 0.0 9 6.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 RKP02827.1 - 0.053 12.8 0.2 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 RKP02827.1 - 0.059 13.8 0.1 2.1 8.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 RKP02827.1 - 0.07 12.5 0.0 10 5.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 RKP02827.1 - 0.1 12.6 0.0 20 5.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF4611 PF15387.6 RKP02827.1 - 0.14 12.4 2.2 13 6.1 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) eRF1_2 PF03464.15 RKP02828.1 - 3.6e-45 153.5 0.0 5.8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RKP02828.1 - 4.8e-38 130.1 0.1 9e-38 129.2 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 RKP02828.1 - 2.5e-19 69.5 0.0 4.2e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 RKP02828.1 - 1.2e-08 35.3 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 RKP02828.1 - 2.4e-08 34.4 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF5643 PF18705.1 RKP02828.1 - 0.0043 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5643) Aa_trans PF01490.18 RKP02829.1 - 4.7e-65 219.9 3.5 2.7e-64 217.4 3.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RKP02829.1 - 0.00052 19.2 6.5 0.00052 19.2 6.5 2.4 1 1 0 2 2 2 2 Tryptophan/tyrosine permease family GWT1 PF06423.12 RKP02829.1 - 0.009 16.1 0.5 0.051 13.7 0.1 2.2 1 1 1 2 2 2 1 GWT1 FAR1 PF03101.15 RKP02830.1 - 0.0013 19.4 0.4 0.003 18.2 0.4 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain SNF2_N PF00176.23 RKP02831.1 - 1.7e-67 227.6 0.0 2.2e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKP02831.1 - 2.8e-12 47.0 0.0 1.1e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 RKP02831.1 - 0.0022 17.9 10.1 0.0044 17.0 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 RKP02831.1 - 0.089 12.8 9.0 0.19 11.8 9.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger IBR PF01485.21 RKP02831.1 - 0.38 11.0 4.9 0.76 10.0 4.9 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 RKP02831.1 - 0.39 10.6 8.8 0.94 9.4 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKP02831.1 - 0.96 9.8 10.9 1.9 8.9 10.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 RKP02831.1 - 5.3 7.0 9.5 13 5.7 9.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKP02831.1 - 8.9 6.3 12.6 0.32 10.9 5.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Hydrophobin PF01185.18 RKP02832.1 - 6.6e-11 42.7 9.9 8.3e-11 42.4 9.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ecm33 PF12454.8 RKP02832.1 - 1.7 8.8 7.4 2.8 8.1 0.6 2.4 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Vac14_Fab1_bd PF12755.7 RKP02833.1 - 5.1e-11 43.0 0.3 4.2e-05 24.1 0.1 3.9 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RKP02833.1 - 6.4e-07 29.7 19.1 0.053 14.0 0.0 7.0 7 0 0 7 7 6 2 HEAT-like repeat HEAT PF02985.22 RKP02833.1 - 1.4e-05 25.0 9.2 0.57 10.6 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat ParcG PF10274.9 RKP02833.1 - 5.6e-05 23.3 0.7 0.24 11.5 0.1 3.6 3 1 1 4 4 4 2 Parkin co-regulated protein CLASP_N PF12348.8 RKP02833.1 - 0.00043 19.9 2.6 0.05 13.2 0.4 2.6 2 1 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 RKP02833.1 - 0.00072 19.6 0.1 0.074 13.1 0.1 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKP02833.1 - 0.015 13.9 8.0 0.82 8.2 0.8 3.3 3 1 0 4 4 4 0 Adaptin N terminal region HEAT_2 PF13646.6 RKP02833.1 - 0.02 15.3 24.5 0.2 12.1 0.7 6.3 5 2 2 7 7 7 0 HEAT repeats DRIM PF07539.12 RKP02833.1 - 0.023 13.0 1.7 0.098 10.9 0.3 2.5 2 1 0 2 2 2 0 Down-regulated in metastasis DUF3385 PF11865.8 RKP02833.1 - 0.037 13.9 0.1 8.1 6.3 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) IFRD PF05004.13 RKP02833.1 - 0.041 13.0 1.8 6.6 5.7 0.0 3.4 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Apolipoprotein PF01442.18 RKP02833.1 - 0.092 12.6 0.2 0.79 9.6 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CT_C_D PF02682.16 RKP02833.1 - 0.1 12.3 0.3 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Arm PF00514.23 RKP02833.1 - 0.18 11.9 10.3 3.4 7.8 0.2 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RTC4 PF14474.6 RKP02834.1 - 1.3e-13 51.2 0.0 3e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain FYDLN_acid PF09538.10 RKP02834.1 - 0.0052 17.4 4.5 0.006 17.3 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-WRNIP1_ubi PF18279.1 RKP02834.1 - 0.066 13.9 0.3 0.17 12.6 0.3 1.7 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF3391 PF11871.8 RKP02834.1 - 4.7 7.7 7.0 0.96 10.0 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) WD40 PF00400.32 RKP02835.1 - 6.9e-09 36.2 3.0 0.37 11.8 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02835.1 - 0.00047 20.4 0.0 1.6 9.1 0.0 3.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Vps39_2 PF10367.9 RKP02836.1 - 2.3e-12 47.3 0.0 5.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 HGTP_anticodon2 PF12745.7 RKP02836.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs PTCB-BRCT PF12738.7 RKP02837.1 - 8.9e-40 134.5 2.1 8.4e-16 57.7 0.0 6.8 6 1 0 6 6 6 4 twin BRCT domain BRCT PF00533.26 RKP02837.1 - 1e-39 134.8 0.0 1.8e-11 44.3 0.0 6.9 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RKP02837.1 - 6.2e-18 65.0 0.0 0.0054 17.1 0.0 7.4 7 0 0 7 7 7 6 BRCT domain, a BRCA1 C-terminus domain WD40 PF00400.32 RKP02838.1 - 9.7e-32 108.5 22.4 2.1e-08 34.7 1.7 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02838.1 - 8.4e-07 29.2 0.1 0.012 15.9 0.1 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP02838.1 - 2e-06 26.7 2.6 0.13 10.8 0.7 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 RKP02838.1 - 5.6e-06 25.9 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 RKP02838.1 - 0.0013 17.7 0.1 1.9 7.3 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MWFE PF15879.5 RKP02839.1 - 7.3e-17 61.3 0.2 9.3e-17 61.0 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit RPN6_N PF18055.1 RKP02840.1 - 1.9e-20 73.3 1.0 1.9e-20 73.3 1.0 2.4 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 RKP02840.1 - 1.5e-17 64.1 0.0 7.7e-17 61.7 0.0 2.3 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 RKP02840.1 - 8e-15 54.3 1.8 1.8e-14 53.1 1.8 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 RKP02840.1 - 0.012 15.0 3.2 0.012 15.0 3.2 1.7 2 0 0 2 2 2 0 MalT-like TPR region RPN7 PF10602.9 RKP02840.1 - 0.036 13.8 0.9 0.46 10.2 0.2 2.6 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 RKP02840.1 - 0.044 14.1 11.1 0.061 13.6 1.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2153 PF09921.9 RKP02840.1 - 0.058 13.2 0.1 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_16 PF13432.6 RKP02840.1 - 0.33 11.6 3.0 0.55 10.9 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S6 PF01250.17 RKP02841.1 - 1.9e-13 50.5 0.0 2.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Svf1_C PF17187.4 RKP02841.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain tRNA-synt_1d PF00750.19 RKP02842.1 - 1e-92 310.8 1.0 1.3e-92 310.5 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 RKP02842.1 - 3.6e-21 75.5 0.1 7.1e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 RKP02842.1 - 0.029 15.0 0.0 0.12 13.0 0.0 2.1 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain Ntox1 PF15500.6 RKP02842.1 - 1.6 9.1 5.9 0.26 11.7 0.4 2.2 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Ribosomal_L35Ae PF01247.18 RKP02843.1 - 3.6e-39 132.8 0.1 4.3e-39 132.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 RKP02843.1 - 0.037 14.2 0.0 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain UDG PF03167.19 RKP02844.1 - 3.6e-18 66.0 0.0 5.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily C2-C2_1 PF11618.8 RKP02845.1 - 0.0012 19.0 0.0 0.0033 17.5 0.0 1.8 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 Peptidase_M22 PF00814.25 RKP02846.1 - 2.8e-84 283.0 0.0 3.3e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 RKP02846.1 - 0.096 12.3 0.0 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Aquarius_N PF16399.5 RKP02847.1 - 1.2e-46 159.3 0.0 4.4e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 RKP02847.1 - 1.2e-21 77.7 0.0 8.7e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 RKP02847.1 - 1.3e-16 60.8 0.0 2.5e-16 59.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKP02847.1 - 1.4e-08 35.2 0.1 1e-07 32.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP02847.1 - 3.7e-07 30.1 7.0 0.0013 18.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 RKP02847.1 - 0.012 16.0 0.6 0.012 16.0 0.6 3.8 4 1 0 4 4 4 0 AAA ATPase domain AAA PF00004.29 RKP02847.1 - 0.045 14.2 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKP02847.1 - 0.13 12.5 0.0 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AA_permease_2 PF13520.6 RKP02848.1 - 4.6e-75 253.1 31.8 5.5e-75 252.8 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RKP02848.1 - 5.4e-29 101.1 25.5 6.1e-29 100.9 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 RKP02849.1 - 8.5e-10 38.4 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02849.1 - 0.025 13.9 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Abhydrolase_3 PF07859.13 RKP02850.1 - 3.7e-32 111.9 0.0 2.6e-23 83.0 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold RRS1 PF04939.12 RKP02852.1 - 3.5e-42 144.0 0.0 3.5e-42 144.0 0.0 2.0 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) bZIP_2 PF07716.15 RKP02853.1 - 1.3e-08 34.8 15.5 3.1e-08 33.6 15.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Period_C PF12114.8 RKP02853.1 - 2.2 7.8 4.1 5.2 6.6 4.1 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region bZIP_1 PF00170.21 RKP02853.1 - 3.5 7.8 12.3 7.4 6.7 12.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor Brix PF04427.18 RKP02854.1 - 4.4e-32 111.8 0.1 5.8e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF4456 PF14644.6 RKP02856.1 - 0.52 10.0 0.0 0.52 10.0 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4456) Cytochrom_B562 PF07361.11 RKP02856.1 - 5.4 7.7 15.1 1.2 9.9 2.1 4.9 4 1 0 4 4 4 0 Cytochrome b562 Ribosomal_L14e PF01929.17 RKP02857.1 - 8.9e-21 74.2 5.9 1.3e-20 73.6 5.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 RKP02857.1 - 0.038 13.9 0.4 0.067 13.2 0.4 1.4 1 0 0 1 1 1 0 KOW motif Sad1_UNC PF07738.13 RKP02857.1 - 0.062 13.3 0.1 0.084 12.9 0.1 1.1 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Ribosomal_L5e PF17144.4 RKP02858.1 - 7.1e-83 276.5 0.4 7.1e-83 276.5 0.4 1.9 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 RKP02858.1 - 8.8e-33 113.1 1.4 8.8e-33 113.1 1.4 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Lsr2 PF11774.8 RKP02858.1 - 0.057 13.6 0.2 0.057 13.6 0.2 1.8 2 0 0 2 2 2 0 Lsr2 Mito_carr PF00153.27 RKP02859.1 - 4.3e-64 212.5 5.8 1.8e-21 75.8 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2722 PF10846.8 RKP02860.1 - 0.0009 18.3 1.8 0.0009 18.3 1.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 RKP02860.1 - 0.068 12.8 12.3 0.11 12.1 12.3 1.2 1 0 0 1 1 1 0 Spt20 family CNOT1_HEAT PF16418.5 RKP02860.1 - 0.14 12.2 1.6 0.25 11.4 1.6 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Inj_translocase PF16928.5 RKP02860.1 - 3.3 7.1 12.4 5.8 6.3 12.4 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome ComC PF03047.14 RKP02861.1 - 0.048 13.5 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 COMC family CcmB PF03379.13 RKP02861.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 CcmB protein JAB PF01398.21 RKP02862.1 - 1.8e-33 115.0 0.0 3.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RKP02862.1 - 4.6e-12 46.3 0.5 7.9e-12 45.6 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 RKP02862.1 - 4e-07 29.8 0.0 7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 RKP02862.1 - 0.039 14.0 0.1 0.09 12.8 0.0 1.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_L29e PF01779.17 RKP02863.1 - 4.4e-19 68.5 9.2 7.3e-19 67.8 9.2 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family AAA PF00004.29 RKP02864.1 - 1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP02864.1 - 2.6e-08 34.5 0.3 1.2e-07 32.3 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKP02864.1 - 4.8e-07 30.1 0.0 1.2e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RKP02864.1 - 6.5e-06 26.2 0.0 4.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RKP02864.1 - 8.9e-06 25.4 1.9 0.022 14.4 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 RKP02864.1 - 1.1e-05 26.0 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RKP02864.1 - 6.4e-05 22.9 0.0 0.00021 21.3 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 RKP02864.1 - 0.00011 21.9 0.1 0.00018 21.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKP02864.1 - 0.0006 20.0 0.1 0.0011 19.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 RKP02864.1 - 0.00068 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 RKP02864.1 - 0.00076 19.3 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 RKP02864.1 - 0.00087 19.2 0.1 0.0021 17.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 RKP02864.1 - 0.0018 18.5 0.1 0.0053 17.0 0.1 1.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 RKP02864.1 - 0.0024 18.3 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 RKP02864.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 RKP02864.1 - 0.0038 17.3 0.0 0.008 16.3 0.0 1.5 1 1 1 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RKP02864.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 RKP02864.1 - 0.0046 16.7 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase Mg_chelatase PF01078.21 RKP02864.1 - 0.0068 15.8 0.4 0.031 13.6 0.0 2.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RKP02864.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 RKP02864.1 - 0.012 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RKP02864.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RKP02864.1 - 0.024 14.4 0.0 0.057 13.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RKP02864.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 RKP02864.1 - 0.037 14.4 0.3 0.12 12.7 0.1 1.8 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 RKP02864.1 - 0.042 13.6 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 RKP02864.1 - 0.054 14.0 0.0 0.082 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 RKP02864.1 - 0.06 12.6 0.0 2.4 7.3 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.13 RKP02864.1 - 0.065 12.4 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 RKP02864.1 - 0.065 13.1 0.0 11 5.8 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 RKP02864.1 - 0.072 12.4 0.1 2.1 7.6 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.17 RKP02864.1 - 0.079 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.23 RKP02864.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 RKP02864.1 - 0.14 12.0 0.0 0.6 10.0 0.0 1.8 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 RKP02864.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 RKP02864.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_C PF03796.15 RKP02864.1 - 0.21 10.9 0.0 1 8.6 0.0 1.7 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain RsgA_GTPase PF03193.16 RKP02864.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 RKP02864.1 - 0.32 10.2 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 RKP02864.1 - 0.38 9.3 0.0 0.47 9.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain TPPK_C PF12555.8 RKP02865.1 - 0.18 11.9 0.3 0.36 10.9 0.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Pup PF05639.11 RKP02866.1 - 0.69 10.9 4.1 33 5.5 1.6 3.0 2 0 0 2 2 2 0 Pup-like protein CLTH PF10607.9 RKP02867.1 - 3.7e-31 108.0 0.1 5.2e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 RKP02867.1 - 0.0022 18.0 0.5 0.043 13.9 0.0 3.0 2 1 0 2 2 2 1 RING-type zinc-finger U-box PF04564.15 RKP02867.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 U-box domain Glyco_trans_4_5 PF16994.5 RKP02867.1 - 0.064 12.9 0.5 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl-transferase family 4 UvdE PF03851.14 RKP02868.1 - 3.5e-77 259.3 0.0 4.2e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE CLTH PF10607.9 RKP02869.1 - 1.8e-35 122.0 0.0 2.3e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RKP02869.1 - 3.8e-09 36.2 0.3 1e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 LisH TPR_14 PF13428.6 RKP02869.1 - 0.1 13.4 1.4 3.8 8.6 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Dpy-30 PF05186.13 RKP02870.1 - 0.00023 20.8 0.2 0.004 16.8 0.2 2.3 2 0 0 2 2 2 1 Dpy-30 motif UPF0113_N PF17833.1 RKP02871.1 - 3.8e-28 97.9 0.0 5.7e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 RKP02871.1 - 3.1e-24 85.0 0.0 4.9e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 RKP02871.1 - 0.038 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Ribosomal_L27A PF00828.19 RKP02872.1 - 7.2e-18 65.5 0.0 1e-17 65.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A WD40 PF00400.32 RKP02873.1 - 1.1e-08 35.5 0.0 0.0022 18.8 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02873.1 - 9.7e-08 32.2 0.0 0.0037 17.5 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Mur_ligase_C PF02875.21 RKP02874.1 - 0.064 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Sec2p PF06428.11 RKP02875.1 - 3e-10 39.9 2.5 5.2e-10 39.2 2.5 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p HALZ PF02183.18 RKP02875.1 - 0.13 12.5 1.7 0.24 11.7 1.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Glyco_hydro_18 PF00704.28 RKP02876.1 - 7.8e-09 35.7 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CDC50 PF03381.15 RKP02877.1 - 1.1e-60 205.6 0.0 1.3e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Arteri_Gl PF00951.18 RKP02877.1 - 0.098 12.5 0.4 0.73 9.6 0.1 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Metallophos PF00149.28 RKP02878.1 - 5.6e-12 46.6 0.7 7.9e-12 46.1 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Haspin_kinase PF12330.8 RKP02879.1 - 6.3e-30 104.3 0.0 7.3e-29 100.8 0.0 2.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKP02879.1 - 0.19 11.6 15.9 0.14 12.0 0.2 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family Clat_adaptor_s PF01217.20 RKP02880.1 - 5.1e-33 114.0 0.2 1.2e-27 96.6 0.1 2.0 1 1 1 2 2 2 2 Clathrin adaptor complex small chain Glyco_hydro_76 PF03663.14 RKP02881.1 - 2.8e-54 185.0 15.8 3.6e-54 184.7 15.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MORN PF02493.20 RKP02882.1 - 1.3e-06 28.0 4.3 0.11 12.5 0.9 3.5 3 0 0 3 3 3 3 MORN repeat AAA_18 PF13238.6 RKP02883.1 - 6.1e-21 75.3 0.0 9.6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKP02883.1 - 6.6e-06 26.5 0.9 3.4e-05 24.1 0.2 2.2 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 RKP02883.1 - 1.4e-05 25.5 0.0 3.3e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 RKP02883.1 - 0.00038 20.9 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP02883.1 - 0.00096 19.6 0.2 0.0015 19.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RKP02883.1 - 0.0032 17.6 0.1 0.0058 16.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKP02883.1 - 0.0066 16.7 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RKP02883.1 - 0.0078 16.2 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 RKP02883.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ADK PF00406.22 RKP02883.1 - 0.0088 16.2 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_29 PF13555.6 RKP02883.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 RKP02883.1 - 0.011 15.5 0.2 0.039 13.7 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 RKP02883.1 - 0.012 15.4 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RKP02883.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 RKP02883.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 RKP02883.1 - 0.014 15.3 0.2 0.024 14.6 0.2 1.4 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 RKP02883.1 - 0.024 13.7 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 RKP02883.1 - 0.03 13.9 1.8 0.087 12.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RKP02883.1 - 0.047 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_19 PF13245.6 RKP02883.1 - 0.053 13.9 0.1 0.094 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKP02883.1 - 0.06 13.7 0.0 0.097 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 RKP02883.1 - 0.074 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 RKP02883.1 - 0.089 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 RKP02883.1 - 0.19 11.1 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 RKP02883.1 - 0.2 11.5 0.4 0.41 10.5 0.4 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RKP02883.1 - 0.26 11.8 0.2 0.35 11.3 0.2 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_M41 PF01434.18 RKP02884.1 - 2.9e-64 216.5 0.0 4.1e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RKP02884.1 - 2.5e-43 147.7 0.0 4.6e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKP02884.1 - 1.8e-11 43.6 0.2 4e-11 42.5 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 RKP02884.1 - 8.2e-09 35.8 0.0 1.8e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 RKP02884.1 - 0.002 18.1 0.0 0.011 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKP02884.1 - 0.0022 17.7 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RKP02884.1 - 0.0036 16.6 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 RKP02884.1 - 0.0056 17.0 0.2 0.6 10.4 0.2 3.0 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 RKP02884.1 - 0.0067 16.5 0.0 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RKP02884.1 - 0.011 16.2 4.0 0.084 13.3 0.4 3.5 3 1 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.6 RKP02884.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RKP02884.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKP02884.1 - 0.087 12.2 0.5 0.36 10.2 0.2 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKP02884.1 - 0.1 12.7 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 RKP02884.1 - 0.19 11.7 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RKP02884.1 - 0.24 11.6 1.9 0.86 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain ASH PF15780.5 RKP02885.1 - 5.2e-12 45.8 0.0 0.0058 16.8 0.0 7.2 7 1 1 8 8 8 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ATG22 PF11700.8 RKP02887.1 - 3.5e-73 246.9 22.7 4.2e-73 246.6 22.7 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like bZIP_2 PF07716.15 RKP02888.1 - 2.2e-05 24.5 19.6 2.2e-05 24.4 14.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 RKP02888.1 - 6e-05 23.1 11.8 6e-05 23.1 11.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 RKP02888.1 - 0.0066 16.7 0.2 0.014 15.7 0.2 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family Shugoshin_N PF07558.11 RKP02888.1 - 0.029 14.2 0.3 0.072 13.0 0.3 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Snf7 PF03357.21 RKP02889.1 - 2.2e-44 151.1 22.9 2.2e-44 151.1 22.9 1.3 2 0 0 2 2 2 1 Snf7 Thioredoxin_7 PF13899.6 RKP02889.1 - 0.013 15.6 1.0 0.032 14.4 1.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like tRNA-synt_2 PF00152.20 RKP02889.1 - 0.27 10.3 2.4 0.15 11.1 0.3 1.7 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) YlqD PF11068.8 RKP02889.1 - 2.6 8.4 16.1 4.9 7.5 10.6 2.3 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.11 RKP02889.1 - 6 7.2 14.9 1 9.6 1.4 2.6 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 ACOX PF01756.19 RKP02890.1 - 1.3e-36 125.8 0.0 2.3e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 RKP02890.1 - 1.4e-26 93.5 0.6 2.5e-26 92.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RKP02890.1 - 1.3e-12 47.8 0.0 3.5e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RKP02890.1 - 0.0086 16.3 0.1 0.0086 16.3 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Curto_V2 PF07325.11 RKP02890.1 - 0.23 11.3 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 Curtovirus V2 protein Mito_carr PF00153.27 RKP02891.1 - 5.3e-63 209.0 0.1 1.3e-26 92.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RA PF00788.23 RKP02893.1 - 0.18 12.5 0.0 33 5.2 0.0 2.5 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain RMI1_N PF08585.12 RKP02894.1 - 1.1e-23 84.2 0.0 1.8e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 RecQ mediated genome instability protein TMEM70 PF06979.12 RKP02897.1 - 0.0077 16.6 1.7 0.31 11.5 0.1 2.2 2 0 0 2 2 2 2 Assembly, mitochondrial proton-transport ATP synth complex Adeno_E1A PF02703.14 RKP02897.1 - 0.019 14.6 0.3 0.033 13.8 0.3 1.3 1 0 0 1 1 1 0 Early E1A protein Sugar_tr PF00083.24 RKP02898.1 - 4.2e-32 111.6 32.1 1e-16 60.9 10.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 RKP02898.1 - 1.1e-26 93.6 40.4 3.7e-20 72.2 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CK_II_beta PF01214.18 RKP02900.1 - 1.2e-73 246.9 0.0 1.3e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HscB_4_cys PF18256.1 RKP02900.1 - 0.49 10.3 6.1 3.9 7.4 0.1 3.0 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Tetraspanin PF00335.20 RKP02901.1 - 5.1e-12 46.0 10.3 9e-12 45.2 10.3 1.3 1 1 0 1 1 1 1 Tetraspanin family MRAP PF15183.6 RKP02901.1 - 1.1 9.2 3.1 3.6 7.6 0.0 2.8 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family Tyrosinase PF00264.20 RKP02902.1 - 5.8e-37 128.1 8.6 1.7e-36 126.6 8.6 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase TAL_FSA PF00923.19 RKP02903.1 - 1.4e-102 342.9 0.4 1.6e-102 342.8 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase STAT_alpha PF01017.20 RKP02904.1 - 0.093 12.6 0.7 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain RTP1_C1 PF10363.9 RKP02905.1 - 6.3e-24 84.3 0.0 8.6e-23 80.7 0.0 2.8 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 SH3_1 PF00018.28 RKP02906.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SH3 domain TssR PF17643.1 RKP02906.1 - 0.083 10.8 0.0 0.097 10.6 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssR ANATO PF01821.18 RKP02907.1 - 0.32 11.9 2.8 0.73 10.7 2.8 1.6 1 0 0 1 1 1 0 Anaphylotoxin-like domain DMT_YdcZ PF04657.13 RKP02909.1 - 0.0002 21.7 0.6 0.00049 20.4 0.6 1.6 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ RGS PF00615.19 RKP02909.1 - 0.085 13.1 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain MIG-14_Wnt-bd PF06664.12 RKP02909.1 - 2.4 7.3 10.0 0.046 12.9 2.7 1.7 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion PDCD2_C PF04194.13 RKP02910.1 - 6.5e-25 88.2 0.6 1.8e-22 80.3 0.3 2.9 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Synaptobrevin PF00957.21 RKP02911.1 - 3.4e-21 74.8 1.0 3.7e-21 74.7 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 RKP02911.1 - 0.079 12.5 0.4 0.093 12.3 0.4 1.0 1 0 0 1 1 1 0 fzo-like conserved region CelTOS PF18659.1 RKP02911.1 - 0.089 13.2 0.1 0.096 13.1 0.1 1.1 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Metallophos PF00149.28 RKP02913.1 - 1.2e-36 127.1 0.1 1.6e-36 126.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 RKP02913.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ribosomal_S17 PF00366.20 RKP02914.1 - 8.3e-28 96.3 0.9 1.8e-27 95.2 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 RKP02914.1 - 2.8e-24 85.3 0.5 2.8e-24 85.3 0.5 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal EMC1_C PF07774.13 RKP02915.1 - 5.8e-49 166.7 0.0 1.2e-48 165.6 0.0 1.4 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal TAFII28 PF04719.14 RKP02916.1 - 3.7e-27 94.2 0.0 5.8e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 RKP02916.1 - 0.0046 17.2 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-B_dimeris PF09026.10 RKP02916.1 - 1.6 9.2 9.1 1.5 9.3 2.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 RKP02917.1 - 5.7e-66 222.6 0.0 6.4e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02917.1 - 3.3e-42 144.6 0.0 3.7e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02917.1 - 3.4e-08 33.1 0.0 7.9e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RKP02917.1 - 0.0012 18.8 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKP02917.1 - 0.0034 16.2 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKP02917.1 - 0.0043 16.4 0.0 0.039 13.3 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dsl1_N PF11988.8 RKP02917.1 - 0.04 12.9 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal GLTP PF08718.11 RKP02918.1 - 6.1e-46 156.4 0.0 7.5e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DXP_reductoisom PF02670.16 RKP02918.1 - 0.043 14.5 0.1 0.065 14.0 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Rap_GAP PF02145.15 RKP02919.1 - 8.7e-10 38.4 0.0 5.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Rap/ran-GAP DUF3774 PF12609.8 RKP02919.1 - 4.9 8.2 7.0 1.4 10.0 1.0 2.8 2 0 0 2 2 2 0 Wound-induced protein Chitin_synth_1 PF01644.17 RKP02920.1 - 1.6e-74 249.3 0.0 2.3e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 RKP02920.1 - 3.9e-27 94.0 0.1 1e-26 92.7 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 RKP02920.1 - 1.7e-24 86.3 2.3 2.6e-19 69.2 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 RKP02920.1 - 2.5e-08 34.1 0.8 2.5e-08 34.1 0.8 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 LRR19-TM PF15176.6 RKP02920.1 - 0.043 13.8 0.8 0.13 12.2 0.8 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain UPF0114 PF03350.16 RKP02920.1 - 0.84 9.9 3.5 2.7 8.2 3.5 1.9 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Phage_holin_3_6 PF07332.11 RKP02921.1 - 0.031 14.3 1.5 0.031 14.3 1.5 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III V-ATPase_G_2 PF16999.5 RKP02921.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF2207 PF09972.9 RKP02921.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_16 PF00722.21 RKP02922.1 - 4.7e-28 97.8 0.1 7.8e-28 97.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase PF00069.25 RKP02923.1 - 5.5e-42 143.9 0.0 1.3e-41 142.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02923.1 - 9e-27 94.0 0.0 2.3e-26 92.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02923.1 - 9.7e-11 41.5 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKP02923.1 - 0.0083 16.1 0.0 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1356 PF07092.12 RKP02923.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Kdo PF06293.14 RKP02923.1 - 0.033 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.20 RKP02924.1 - 4.8e-44 150.8 17.1 7.1e-28 97.9 6.8 2.0 2 0 0 2 2 2 2 Major intrinsic protein zf-C2H2_4 PF13894.6 RKP02925.1 - 0.18 12.8 4.5 2.2 9.3 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger CHCH PF06747.13 RKP02926.1 - 3.7e-07 30.1 5.7 5.9e-07 29.5 5.7 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 RKP02926.1 - 0.0081 16.2 3.3 0.041 13.9 0.6 2.1 1 1 2 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 RKP02926.1 - 0.014 15.4 0.4 0.97 9.5 0.1 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Y_phosphatase2 PF03162.13 RKP02927.1 - 7.1e-36 123.3 0.0 7.9e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKP02927.1 - 0.0059 16.6 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family NitrOD2 PF18550.1 RKP02927.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.5 2 0 0 2 2 2 0 Nitrososphaera output domain 2 Pantoate_transf PF02548.15 RKP02928.1 - 2.7e-102 341.6 0.4 3e-102 341.4 0.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 RKP02928.1 - 0.00048 19.6 0.1 0.00078 19.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase stn_TNFRSF12A PF12191.8 RKP02929.1 - 0.052 13.8 0.3 0.2 11.9 0.3 2.0 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain vATP-synt_AC39 PF01992.16 RKP02930.1 - 8.6e-113 377.2 0.2 9.7e-113 377.1 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit ChAPs PF09295.10 RKP02931.1 - 2.9e-128 428.3 0.0 5e-128 427.5 0.0 1.4 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 RKP02931.1 - 6.9e-05 23.3 0.2 0.71 10.4 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat SUIM_assoc PF16619.5 RKP02931.1 - 0.06 13.4 11.5 0.082 13.0 4.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3827 PF12877.7 RKP02931.1 - 0.11 10.8 7.0 0.16 10.3 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Hid1 PF12722.7 RKP02931.1 - 0.19 9.8 3.3 0.27 9.3 3.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CiPC PF15800.5 RKP02931.1 - 0.32 10.7 10.9 0.5 10.0 10.9 1.2 1 0 0 1 1 1 0 Clock interacting protein circadian SRP-alpha_N PF04086.13 RKP02931.1 - 0.57 10.1 4.8 0.83 9.5 4.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mis12 PF05859.12 RKP02932.1 - 5.5e-24 84.8 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DivIC PF04977.15 RKP02932.1 - 0.0062 16.3 2.2 0.011 15.4 2.2 1.3 1 0 0 1 1 1 1 Septum formation initiator ADIP PF11559.8 RKP02932.1 - 0.1 12.7 0.8 0.21 11.6 0.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 RKP02932.1 - 2.7 7.2 7.7 0.27 10.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cwf_Cwc_15 PF04889.12 RKP02932.1 - 2.7 7.7 7.2 0.48 10.1 3.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ras PF00071.22 RKP02933.1 - 3.8e-47 159.9 0.0 4.5e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP02933.1 - 4.5e-27 94.7 0.0 9.8e-27 93.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP02933.1 - 2.7e-08 33.5 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 RKP02933.1 - 4.4e-05 23.8 0.1 0.00033 21.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 RKP02933.1 - 0.0071 15.5 0.2 0.99 8.5 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Pox_A32 PF04665.12 RKP02933.1 - 0.024 14.1 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.23 RKP02933.1 - 0.034 14.2 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 RKP02933.1 - 0.046 13.2 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RKP02933.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 RKP02933.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgoMid PF16487.5 RKP02933.1 - 0.065 13.5 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 RKP02933.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RKP02933.1 - 0.1 12.5 0.1 9.6 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 RKP02933.1 - 0.13 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RKP02933.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 RKP02933.1 - 0.16 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RKP02933.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Ribosomal_S25 PF03297.15 RKP02934.1 - 8.1e-34 115.9 0.9 8.9e-34 115.7 0.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 RKP02934.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain HTH_24 PF13412.6 RKP02934.1 - 0.013 15.1 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DDRGK PF09756.9 RKP02934.1 - 0.013 15.1 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 DDRGK domain MarR_2 PF12802.7 RKP02934.1 - 0.034 14.0 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 MarR family GntR PF00392.21 RKP02934.1 - 0.055 13.1 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 RKP02934.1 - 0.086 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 HTH domain TRAM_2 PF18693.1 RKP02934.1 - 0.092 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 TRAM domain EAP30 PF04157.16 RKP02934.1 - 0.099 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 RKP02934.1 - 0.1 12.2 1.7 0.14 11.7 1.4 1.5 1 1 0 1 1 1 0 CodY helix-turn-helix domain PAPA-1 PF04795.12 RKP02935.1 - 3.4e-14 53.4 1.6 3.4e-14 53.4 1.6 5.0 2 1 2 4 4 4 1 PAPA-1-like conserved region RGS PF00615.19 RKP02936.1 - 0.0017 18.6 0.1 0.002 18.4 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pyr_redox_2 PF07992.14 RKP02937.1 - 4.6e-44 150.8 1.3 5.5e-44 150.6 1.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKP02937.1 - 1.7e-16 60.5 1.3 6.7e-14 52.2 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKP02937.1 - 2.8e-14 53.1 0.1 3.7e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RKP02937.1 - 3.1e-05 23.3 0.0 0.00033 19.9 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 RKP02937.1 - 0.00042 20.7 0.1 0.01 16.3 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 RKP02937.1 - 0.0021 17.4 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 RKP02937.1 - 0.019 14.3 0.5 0.084 12.2 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RKP02937.1 - 0.021 15.1 1.0 0.68 10.2 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain SIP PF04954.13 RKP02937.1 - 0.052 14.1 0.1 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting protein HI0933_like PF03486.14 RKP02937.1 - 0.12 11.0 0.8 14 4.2 0.1 2.8 2 1 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 RKP02937.1 - 0.13 11.3 5.2 1.8 7.6 0.7 3.2 3 1 1 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RKP02937.1 - 0.25 10.4 7.8 0.32 10.0 0.4 3.6 2 2 1 4 4 4 0 FAD binding domain zf-C2H2 PF00096.26 RKP02938.1 - 1.4e-13 50.5 15.9 0.00033 20.9 5.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP02938.1 - 2.8e-11 43.2 12.9 0.0004 21.0 3.2 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP02938.1 - 1e-08 35.2 12.0 8.1e-05 22.9 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RKP02938.1 - 4.3e-06 26.6 7.5 0.057 13.4 0.0 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKP02938.1 - 1e-05 25.6 0.4 0.021 15.1 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RKP02938.1 - 0.0017 18.0 15.9 0.1 12.4 0.3 3.9 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 RKP02938.1 - 0.0036 17.6 1.9 3.2 8.2 0.8 2.9 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RKP02938.1 - 0.024 15.1 3.2 0.099 13.1 2.4 2.3 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 RKP02938.1 - 0.074 13.5 1.8 12 6.4 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 RKP02938.1 - 0.11 12.8 2.6 0.77 10.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon zf-Dof PF02701.15 RKP02938.1 - 0.41 10.8 5.0 1.3 9.2 4.8 1.9 1 1 0 1 1 1 0 Dof domain, zinc finger zf-C2H2_11 PF16622.5 RKP02938.1 - 0.54 10.1 12.2 1.8 8.4 0.7 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type RSN1_7TM PF02714.15 RKP02939.1 - 1.3e-63 214.9 16.1 1.3e-63 214.9 16.1 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 RKP02939.1 - 4.8e-23 81.6 7.5 4.8e-23 81.6 7.5 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RKP02939.1 - 2.6e-12 47.3 0.0 5e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF2755 PF10954.8 RKP02939.1 - 0.01 15.7 1.7 0.064 13.2 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DUF1358 PF07096.11 RKP02939.1 - 0.13 12.3 0.9 0.26 11.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) Methyltransf_31 PF13847.6 RKP02941.1 - 2.1e-08 34.1 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RKP02941.1 - 9.2e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 RKP02941.1 - 3.7e-05 24.3 0.0 8.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKP02941.1 - 8.7e-05 22.1 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 RKP02941.1 - 0.00027 20.6 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 RKP02941.1 - 0.00054 19.5 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 RKP02941.1 - 0.001 18.4 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Cons_hypoth95 PF03602.15 RKP02941.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 RKP02941.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 RKP02941.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 RKP02941.1 - 0.037 14.7 0.4 0.11 13.2 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain AviRa PF11599.8 RKP02941.1 - 0.083 12.3 0.0 0.44 10.0 0.0 1.8 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Pkinase PF00069.25 RKP02942.1 - 1.8e-73 247.2 0.0 2.1e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02942.1 - 1.8e-38 132.3 0.0 2.2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02942.1 - 0.00018 20.9 0.1 0.00058 19.3 0.0 1.8 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 RKP02942.1 - 0.043 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 RKP02942.1 - 0.091 12.7 0.0 0.58 10.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RKP02942.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_J PF04911.12 RKP02943.1 - 4.1e-06 26.3 1.6 5.1e-06 26.0 1.2 1.4 1 1 0 1 1 1 1 ATP synthase j chain ORC5_C PF14630.6 RKP02944.1 - 9.2e-48 163.2 0.0 1.3e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 RKP02944.1 - 7.6e-08 32.9 0.0 2.8e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP02944.1 - 0.00024 21.4 0.0 0.003 17.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RKP02944.1 - 0.00042 20.3 0.0 0.00058 19.8 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 RKP02944.1 - 0.024 15.2 0.0 0.039 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKP02944.1 - 0.059 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 RKP02944.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1543 PF07566.12 RKP02945.1 - 0.14 11.9 0.8 0.37 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) UBA PF00627.31 RKP02946.1 - 7.8e-27 92.8 4.5 1.1e-12 47.6 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 RKP02946.1 - 2e-20 72.3 10.2 2e-20 72.3 10.2 1.7 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 RKP02946.1 - 1.2e-17 63.5 0.1 1.9e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RKP02946.1 - 8.1e-07 28.8 0.2 8.1e-07 28.8 0.2 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 RKP02946.1 - 5.1e-05 23.8 0.3 0.00022 21.7 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RKP02946.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like SUIM_assoc PF16619.5 RKP02946.1 - 0.0017 18.4 1.9 0.0054 16.8 1.9 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 RKP02946.1 - 0.58 9.7 10.0 1.2 8.7 10.0 1.5 1 0 0 1 1 1 0 Spt20 family Ubiquitin_4 PF18036.1 RKP02946.1 - 3.9 7.6 5.9 5.5 7.1 0.1 2.6 2 1 1 3 3 3 0 Ubiquitin-like domain WD40 PF00400.32 RKP02947.1 - 3.5e-39 132.1 18.4 7.7e-06 26.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP02947.1 - 2e-16 60.0 0.0 0.0019 18.5 0.1 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKP02947.1 - 4.7e-05 23.3 0.0 0.18 11.7 0.0 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 RKP02947.1 - 7.5e-05 22.2 0.0 0.00034 20.0 0.0 2.0 1 1 1 2 2 2 1 WD40-like domain Nup160 PF11715.8 RKP02947.1 - 0.016 13.9 0.1 0.89 8.1 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 RKP02947.1 - 0.098 11.2 0.0 0.25 9.9 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3275 PF11679.8 RKP02949.1 - 7.8 6.4 9.2 4.6 7.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Profilin PF00235.19 RKP02950.1 - 3.2e-24 85.6 0.0 3.5e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Bromodomain PF00439.25 RKP02951.1 - 1.4e-13 50.7 0.0 2.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain GATA PF00320.27 RKP02951.1 - 2.6e-12 46.1 4.0 6.9e-12 44.8 4.0 1.8 1 0 0 1 1 1 1 GATA zinc finger BET PF17035.5 RKP02951.1 - 2.1e-08 34.2 0.0 0.00091 19.4 0.0 2.3 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation Sel1 PF08238.12 RKP02951.1 - 1.2e-05 25.8 3.5 0.094 13.4 0.0 3.5 3 0 0 3 3 3 2 Sel1 repeat DUF1682 PF07946.14 RKP02952.1 - 8.3e-28 97.5 0.0 5.8e-22 78.3 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1682) Osteopontin PF00865.18 RKP02952.1 - 0.0032 17.0 14.4 0.0032 17.0 14.4 2.1 2 0 0 2 2 2 1 Osteopontin Cwf_Cwc_15 PF04889.12 RKP02952.1 - 0.065 13.0 18.4 0.34 10.6 1.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 RKP02952.1 - 0.1 13.1 4.5 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) SpoIIIAH PF12685.7 RKP02952.1 - 0.73 9.6 4.9 4.2 7.1 0.3 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Apt1 PF10351.9 RKP02952.1 - 1.6 7.5 10.2 0.2 10.5 0.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain TFIIA PF03153.13 RKP02952.1 - 4.6 7.1 16.9 6.2 6.7 1.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 RKP02953.1 - 4.1e-18 65.0 1.1 6.8e-18 64.3 1.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 RKP02953.1 - 0.065 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain YdaS_antitoxin PF15943.5 RKP02953.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT ASFV_J13L PF05568.11 RKP02954.1 - 0.00025 20.8 7.1 0.074 12.8 1.5 3.0 1 1 1 2 2 2 2 African swine fever virus J13L protein APG12 PF04110.13 RKP02956.1 - 1.8e-28 98.8 0.0 2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 RKP02956.1 - 0.0039 17.4 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pkinase PF00069.25 RKP02957.1 - 3.9e-34 118.2 0.0 5.6e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02957.1 - 6.7e-26 91.1 0.0 3.6e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKP02957.1 - 1.5e-09 37.6 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP02957.1 - 0.0047 16.3 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP02957.1 - 0.084 12.8 0.1 0.084 12.8 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.29 RKP02958.1 - 3.4e-45 153.7 0.1 1.4e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKP02958.1 - 1.3e-09 38.2 0.1 3.3e-09 36.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 RKP02958.1 - 3e-09 36.7 0.1 2.5e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RKP02958.1 - 3.8e-08 33.0 0.1 1e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RKP02958.1 - 4.7e-08 33.3 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 RKP02958.1 - 7.7e-08 32.9 0.3 2e-05 25.1 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 RKP02958.1 - 8.4e-06 25.1 0.2 2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 RKP02958.1 - 6.2e-05 23.3 1.5 0.011 16.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 RKP02958.1 - 0.00028 21.4 0.0 0.0011 19.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 RKP02958.1 - 0.00033 20.6 0.1 0.025 14.5 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 RKP02958.1 - 0.00034 20.4 0.0 0.00095 18.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 RKP02958.1 - 0.00038 20.7 0.0 0.00081 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RKP02958.1 - 0.00055 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 RKP02958.1 - 0.00097 19.2 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 RKP02958.1 - 0.0024 17.4 0.1 0.015 14.8 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 RKP02958.1 - 0.0026 17.5 0.1 0.0061 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RKP02958.1 - 0.0044 16.8 0.2 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 RKP02958.1 - 0.0049 17.0 0.0 0.015 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 RKP02958.1 - 0.0054 16.7 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 NTPase TniB PF05621.11 RKP02958.1 - 0.0073 15.7 0.0 0.61 9.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 RKP02958.1 - 0.0075 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RKP02958.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RKP02958.1 - 0.0092 15.9 0.1 0.071 13.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 RKP02958.1 - 0.011 15.3 0.8 0.037 13.6 0.3 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKP02958.1 - 0.019 14.7 0.1 0.045 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 RKP02958.1 - 0.02 14.2 0.9 0.48 9.7 0.0 2.5 3 0 0 3 3 3 0 KaiC TIP49 PF06068.13 RKP02958.1 - 0.021 14.0 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Clathrin PF00637.20 RKP02958.1 - 0.026 14.4 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Region in Clathrin and VPS AAA_11 PF13086.6 RKP02958.1 - 0.036 13.8 0.1 0.082 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 RKP02958.1 - 0.037 14.4 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 RKP02958.1 - 0.048 13.4 0.2 1.2 8.9 0.0 2.7 3 1 0 3 3 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 RKP02958.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein SPACA9 PF15120.6 RKP02958.1 - 0.054 13.3 0.3 6.2 6.6 0.1 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 ATPase_2 PF01637.18 RKP02958.1 - 0.088 12.7 0.5 0.51 10.2 0.1 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 RKP02958.1 - 0.092 13.3 0.1 0.42 11.1 0.0 2.4 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.17 RKP02958.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 RKP02958.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 RKP02959.1 - 4.7e-06 26.2 0.0 6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RKP02959.1 - 4.9e-05 23.5 0.0 0.00021 21.5 0.0 1.8 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 RKP02959.1 - 6e-05 23.0 0.0 7.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 RKP02959.1 - 0.069 11.8 0.0 0.083 11.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.9 RKP02960.1 - 1.6e-38 132.1 0.1 2.4e-38 131.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RKP02960.1 - 4.4e-12 46.5 0.0 9.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RKP02960.1 - 1.8e-06 27.8 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PseudoU_synth_1 PF01416.20 RKP02960.1 - 0.12 12.8 0.1 2 8.9 0.1 2.4 1 1 0 1 1 1 0 tRNA pseudouridine synthase Tfb4 PF03850.14 RKP02961.1 - 7.6e-78 261.8 5.4 8.8e-60 202.5 2.8 2.0 1 1 0 2 2 2 2 Transcription factor Tfb4 Adap_comp_sub PF00928.21 RKP02962.1 - 2.6e-12 46.7 0.0 4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 RKP02962.1 - 0.00013 22.0 0.2 0.00023 21.1 0.1 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Coilin_N PF15862.5 RKP02962.1 - 1.4 8.7 5.0 3.7 7.3 0.4 2.2 2 0 0 2 2 2 0 Coilin N-terminus TFIIA PF03153.13 RKP02962.1 - 1.6 8.6 8.6 0.21 11.5 3.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 RKP02962.1 - 3.4 7.8 16.4 0.19 11.8 5.2 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Borrelia_P83 PF05262.11 RKP02962.1 - 9.8 4.5 8.7 0.1 11.1 0.5 1.6 2 0 0 2 2 2 0 Borrelia P83/100 protein Sfi1 PF08457.10 RKP02964.1 - 0.0061 15.2 238.8 0.034 12.7 18.4 8.7 2 2 5 7 7 7 5 Sfi1 spindle body protein MCM PF00493.23 RKP02965.1 - 1.2e-105 351.5 0.4 1.7e-105 351.1 0.4 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RKP02965.1 - 9.1e-38 129.0 0.4 2.5e-35 121.1 0.0 2.5 2 0 0 2 2 2 2 MCM OB domain MCM_lid PF17855.1 RKP02965.1 - 1.4e-22 79.9 0.6 3.9e-22 78.5 0.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 RKP02965.1 - 2.6e-17 63.0 0.0 6.6e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 RKP02965.1 - 6.6e-17 62.0 0.0 1.6e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RKP02965.1 - 9.6e-10 38.2 0.1 1.5e-07 31.0 0.0 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RKP02965.1 - 1.4e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKP02965.1 - 2.1e-05 24.5 0.0 5.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 RKP02965.1 - 0.00011 21.9 0.1 0.00024 20.8 0.1 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain zf-piccolo PF05715.13 RKP02965.1 - 0.016 15.4 0.2 0.029 14.5 0.2 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger RRM_1 PF00076.22 RKP02966.1 - 1.9e-28 98.1 0.9 4.8e-08 32.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKP02966.1 - 1.6e-08 34.3 0.0 0.044 13.6 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 RKP02966.1 - 3.4e-07 30.3 0.0 0.17 12.0 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 RKP02966.1 - 0.011 15.7 0.1 6.5 6.8 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Phage_T4_Ndd PF06591.11 RKP02966.1 - 0.11 12.3 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) RRM_3 PF08777.11 RKP02966.1 - 0.21 11.6 0.1 31 4.7 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif tRNA-synt_2 PF00152.20 RKP02967.1 - 9e-89 297.6 0.0 1.2e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RKP02967.1 - 6.6e-10 38.8 0.0 1.1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 RKP02967.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Cpn60_TCP1 PF00118.24 RKP02968.1 - 2.8e-150 501.2 12.9 3.2e-150 501.0 12.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 RKP02968.1 - 0.17 11.8 10.2 0.029 14.3 5.8 2.0 2 1 0 2 2 2 0 MftR C-terminal domain CHD5 PF04420.14 RKP02969.1 - 5.3e-21 75.1 0.0 6.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 CHD5-like protein MMPL PF03176.15 RKP02969.1 - 0.033 13.1 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 MMPL family ParcG PF10274.9 RKP02971.1 - 4e-19 69.5 0.0 5.4e-18 65.8 0.0 2.2 1 1 0 1 1 1 1 Parkin co-regulated protein Tic22 PF04278.12 RKP02971.1 - 0.067 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Tic22-like family MMS19_C PF12460.8 RKP02971.1 - 0.076 12.1 0.2 0.12 11.4 0.2 1.3 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal Pkinase PF00069.25 RKP02972.1 - 3.8e-54 183.8 0.0 4.8e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02972.1 - 9.3e-42 143.1 0.0 1.2e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP02972.1 - 0.00026 19.9 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RKP02972.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RKP02972.1 - 0.3 11.0 4.4 1.3 8.9 0.9 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.29 RKP02973.1 - 1.1e-31 109.9 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP02973.1 - 1.9e-07 31.6 0.8 2e-06 28.3 0.8 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 RKP02973.1 - 2.4e-06 27.9 0.2 6.2e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RKP02973.1 - 9.4e-06 25.7 0.3 0.00097 19.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP02973.1 - 1.8e-05 25.1 0.3 0.00061 20.1 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 RKP02973.1 - 2.3e-05 24.6 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP02973.1 - 0.0003 21.3 0.0 0.00051 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RKP02973.1 - 0.00049 20.1 0.0 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 RKP02973.1 - 0.00055 19.9 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 RKP02973.1 - 0.00095 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase TIP49 PF06068.13 RKP02973.1 - 0.00096 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 RKP02973.1 - 0.001 18.8 1.2 0.0033 17.2 1.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RKP02973.1 - 0.0011 19.0 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RKP02973.1 - 0.0015 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 RKP02973.1 - 0.0031 17.1 0.7 0.014 15.0 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_6 PF12774.7 RKP02973.1 - 0.0037 16.3 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DUF815 PF05673.13 RKP02973.1 - 0.0039 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 RKP02973.1 - 0.0074 16.8 0.1 0.038 14.5 0.0 1.8 1 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 RKP02973.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 RKP02973.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 RKP02973.1 - 0.013 15.2 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain IPT PF01745.16 RKP02973.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase Rad17 PF03215.15 RKP02973.1 - 0.023 14.6 0.0 0.052 13.5 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 RKP02973.1 - 0.023 14.5 0.0 0.024 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RKP02973.1 - 0.037 13.4 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 RKP02973.1 - 0.042 14.2 0.1 0.083 13.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 RKP02973.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 RKP02973.1 - 0.051 13.0 0.0 0.65 9.4 0.0 2.6 2 1 1 3 3 3 0 Bacterial TniB protein AAA_23 PF13476.6 RKP02973.1 - 0.057 13.9 0.0 0.075 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKP02973.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 KaiC T2SSE PF00437.20 RKP02973.1 - 0.077 12.0 0.2 0.13 11.3 0.0 1.5 2 0 0 2 2 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 RKP02973.1 - 0.096 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 RKP02973.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 RKP02973.1 - 0.13 12.1 0.0 1.1 9.1 0.1 2.1 1 1 0 2 2 2 0 NTPase PhoH PF02562.16 RKP02973.1 - 0.16 11.4 0.6 0.28 10.6 0.2 1.5 2 0 0 2 2 1 0 PhoH-like protein cobW PF02492.19 RKP02973.1 - 0.18 11.3 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 RKP02973.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_8 PF12780.7 RKP02973.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_2 PF07724.14 RKP02973.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) dNK PF01712.19 RKP02973.1 - 0.22 11.3 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase PduV-EutP PF10662.9 RKP02973.1 - 0.27 11.0 0.0 0.41 10.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 RKP02973.1 - 0.3 10.3 0.0 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RRM_1 PF00076.22 RKP02974.1 - 9.6e-30 102.2 0.0 2.1e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 RKP02974.1 - 2.3e-21 74.2 0.0 0.00049 19.6 0.0 5.9 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 RKP02974.1 - 0.0035 17.2 0.0 0.59 10.0 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cofilin_ADF PF00241.20 RKP02976.1 - 2.6e-19 69.2 0.0 3.8e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein ECH_1 PF00378.20 RKP02977.1 - 7.3e-34 117.2 0.0 1.4e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKP02977.1 - 8.1e-11 42.0 0.0 1.6e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chitin_synth_2 PF03142.15 RKP02978.1 - 2.5e-222 739.2 0.2 1.2e-221 737.0 0.8 1.8 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 RKP02978.1 - 1.8e-66 224.7 0.0 1.4e-65 221.8 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 RKP02978.1 - 3.6e-12 46.2 1.5 5.8e-08 32.8 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 RKP02978.1 - 1.8e-11 43.8 0.0 1.5e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 RKP02978.1 - 7.1e-10 39.1 2.1 1.7e-09 37.9 2.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKP02978.1 - 2.2e-08 34.3 0.0 1.1e-07 32.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RKP02978.1 - 0.0004 20.2 0.0 0.049 13.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RKP02978.1 - 0.014 14.9 0.0 0.041 13.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 AAA_5 PF07728.14 RKP02979.1 - 8.5e-118 388.6 0.0 3.1e-26 92.0 0.0 9.5 7 2 1 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 RKP02979.1 - 1.5e-41 140.8 1.0 6.9e-12 45.5 0.4 5.5 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 RKP02979.1 - 3.9e-28 97.6 1.1 1.1e-26 93.0 0.2 3.3 3 0 0 3 3 3 1 Midasin AAA lid domain AAA_16 PF13191.6 RKP02979.1 - 2.1e-27 96.6 6.8 0.0014 19.0 0.0 7.8 7 1 0 7 7 6 6 AAA ATPase domain AAA_7 PF12775.7 RKP02979.1 - 6.4e-27 94.2 3.1 7.9e-06 25.5 0.4 6.7 7 0 0 7 7 6 5 P-loop containing dynein motor region AAA PF00004.29 RKP02979.1 - 1.5e-26 93.4 0.0 0.00032 21.1 0.0 6.8 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 RKP02979.1 - 3.6e-25 88.3 0.0 7.6e-09 35.5 0.0 8.9 8 2 1 9 9 8 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKP02979.1 - 9.3e-22 77.8 0.1 0.024 14.9 0.0 7.0 6 1 0 6 6 6 5 AAA domain Dynein_heavy PF03028.15 RKP02979.1 - 3.5e-20 72.3 0.0 1.3e-05 25.3 0.0 6.4 6 0 0 6 6 5 2 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 RKP02979.1 - 1.8e-19 70.1 0.3 0.0065 16.2 0.1 6.5 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_6 PF12774.7 RKP02979.1 - 7.3e-19 67.9 0.1 0.00022 20.3 0.1 8.3 10 0 0 10 10 9 3 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 RKP02979.1 - 1.3e-17 64.6 0.0 0.18 12.4 0.0 6.7 6 0 0 6 6 6 3 AAA domain TsaE PF02367.17 RKP02979.1 - 2.9e-16 59.6 1.8 0.0097 15.9 0.1 6.4 6 0 0 6 6 6 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 RKP02979.1 - 4.4e-16 59.6 0.2 0.15 12.6 0.0 6.3 6 0 0 6 6 6 4 ABC transporter Sigma54_activ_2 PF14532.6 RKP02979.1 - 2e-15 57.1 0.1 0.001 19.2 0.0 6.1 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_30 PF13604.6 RKP02979.1 - 1.1e-14 54.6 2.2 0.17 11.6 0.0 6.9 6 1 1 7 7 6 4 AAA domain AAA_33 PF13671.6 RKP02979.1 - 1.5e-14 54.4 0.2 0.11 12.7 0.0 6.6 6 0 0 6 6 6 2 AAA domain AAA_29 PF13555.6 RKP02979.1 - 4e-14 52.1 0.2 0.18 11.5 0.0 6.6 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_14 PF13173.6 RKP02979.1 - 1.4e-13 51.1 0.0 0.049 13.7 0.0 6.8 6 1 1 7 7 7 2 AAA domain RNA_helicase PF00910.22 RKP02979.1 - 2.9e-13 50.1 0.7 0.48 10.8 0.0 6.4 6 0 0 6 6 6 1 RNA helicase DUF815 PF05673.13 RKP02979.1 - 6.4e-12 45.2 0.7 0.065 12.4 0.0 6.0 6 0 0 6 6 6 3 Protein of unknown function (DUF815) NACHT PF05729.12 RKP02979.1 - 8.4e-12 45.3 6.4 0.47 10.4 0.0 6.6 6 0 0 6 6 6 3 NACHT domain RsgA_GTPase PF03193.16 RKP02979.1 - 1.3e-11 44.7 0.2 0.31 10.9 0.1 6.3 6 0 0 6 6 6 3 RsgA GTPase IstB_IS21 PF01695.17 RKP02979.1 - 1.4e-11 44.4 1.4 0.3 10.8 0.0 6.3 6 0 0 6 6 6 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKP02979.1 - 7.5e-11 41.8 6.0 1.5 8.2 0.0 8.4 8 1 1 9 9 9 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 RKP02979.1 - 8e-11 42.5 3.9 0.089 13.1 0.0 6.6 6 0 0 6 6 6 2 AAA domain T2SSE PF00437.20 RKP02979.1 - 1.7e-10 40.4 0.1 0.072 12.1 0.1 6.0 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_25 PF13481.6 RKP02979.1 - 2.1e-10 40.5 3.2 0.94 9.0 0.0 6.4 6 0 0 6 6 6 1 AAA domain Zeta_toxin PF06414.12 RKP02979.1 - 2.4e-10 40.0 1.2 1.2 8.4 0.0 6.5 6 0 0 6 6 6 1 Zeta toxin AAA_28 PF13521.6 RKP02979.1 - 3e-10 40.6 6.8 1.9 8.7 0.0 6.5 6 0 0 6 6 6 1 AAA domain Rad17 PF03215.15 RKP02979.1 - 6.9e-10 39.2 0.5 0.49 10.3 0.0 6.2 6 0 0 6 6 6 1 Rad17 P-loop domain RuvB_N PF05496.12 RKP02979.1 - 9.2e-10 38.5 2.2 1 9.1 0.0 6.6 7 0 0 7 7 6 2 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 RKP02979.1 - 1.1e-08 35.3 0.1 0.06 13.1 0.0 5.4 5 0 0 5 5 5 1 AAA domain AAA_24 PF13479.6 RKP02979.1 - 1.7e-08 34.4 0.6 0.078 12.7 0.0 6.3 7 0 0 7 7 6 1 AAA domain AAA_23 PF13476.6 RKP02979.1 - 2.3e-07 31.5 0.2 8.4 6.8 0.0 5.6 5 0 0 5 5 5 0 AAA domain TniB PF05621.11 RKP02979.1 - 4.5e-07 29.5 0.0 0.32 10.4 0.0 6.2 7 0 0 7 7 6 1 Bacterial TniB protein cobW PF02492.19 RKP02979.1 - 1.9e-06 27.6 4.1 5.5 6.5 0.0 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 RKP02979.1 - 2.3e-06 27.8 2.7 5.3 7.3 0.1 6.1 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 RKP02979.1 - 2.7e-06 27.5 2.2 1.7 8.6 0.1 5.4 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 RKP02979.1 - 3.5e-06 26.8 4.9 0.89 9.3 0.1 5.3 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 RKP02979.1 - 7.1e-06 26.0 0.4 11 5.9 0.0 6.0 7 0 0 7 7 5 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 RKP02979.1 - 1e-05 25.5 10.0 1.4 8.8 0.0 5.8 6 0 0 6 6 5 1 NTPase AAA_9 PF12781.7 RKP02979.1 - 1.5e-05 24.2 0.0 0.33 10.0 0.0 4.8 5 0 0 5 5 5 1 ATP-binding dynein motor region SRP54 PF00448.22 RKP02979.1 - 2e-05 24.3 11.7 0.073 12.7 0.5 6.3 7 0 0 7 7 6 1 SRP54-type protein, GTPase domain DEAD PF00270.29 RKP02979.1 - 2.6e-05 24.1 0.5 5.1 6.8 0.1 4.9 5 0 0 5 5 5 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 RKP02979.1 - 3.9e-05 23.5 0.0 2.2 8.0 0.0 5.0 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 RKP02979.1 - 5.4e-05 23.3 0.0 15 5.7 0.0 5.3 5 0 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 RKP02979.1 - 6.1e-05 23.1 0.5 17 5.5 0.0 5.6 6 0 0 6 6 5 0 50S ribosome-binding GTPase IPT PF01745.16 RKP02979.1 - 7.8e-05 22.2 1.2 0.1 12.0 0.0 3.5 4 0 0 4 4 2 1 Isopentenyl transferase FtsK_SpoIIIE PF01580.18 RKP02979.1 - 8.2e-05 22.1 3.4 0.27 10.5 0.0 4.5 5 0 0 5 5 4 1 FtsK/SpoIIIE family ATPase_2 PF01637.18 RKP02979.1 - 8.7e-05 22.5 0.0 4 7.3 0.0 5.1 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea AAA_8 PF12780.7 RKP02979.1 - 0.00025 20.5 0.1 0.99 8.7 0.0 4.3 5 1 0 5 5 4 1 P-loop containing dynein motor region D4 ATP_bind_1 PF03029.17 RKP02979.1 - 0.00038 20.3 6.8 4.3 7.0 0.1 5.4 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein TIP49 PF06068.13 RKP02979.1 - 0.00041 19.6 3.5 3.3 6.8 0.0 5.0 6 0 0 6 6 6 0 TIP49 P-loop domain ATPase PF06745.13 RKP02979.1 - 0.00045 19.6 0.4 1.6 8.0 0.0 5.0 6 0 0 6 6 5 1 KaiC DAP3 PF10236.9 RKP02979.1 - 0.00056 19.2 0.3 1.2 8.2 0.0 4.5 5 0 0 5 5 5 1 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 RKP02979.1 - 0.00059 19.0 0.1 2.9 6.9 0.0 4.6 5 0 0 5 5 5 0 MCM P-loop domain dNK PF01712.19 RKP02979.1 - 0.00067 19.6 3.1 38 4.1 0.0 5.4 6 0 0 6 6 5 0 Deoxynucleoside kinase AAA_2 PF07724.14 RKP02979.1 - 0.00072 19.7 0.1 18 5.4 0.0 5.8 7 1 0 7 7 5 0 AAA domain (Cdc48 subfamily) Hpr_kinase_C PF07475.12 RKP02979.1 - 0.0025 17.3 0.3 1.3 8.5 0.0 4.3 5 0 0 5 5 4 1 HPr Serine kinase C-terminal domain SRPRB PF09439.10 RKP02979.1 - 0.0031 17.0 1.7 38 3.6 0.1 5.1 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RKP02979.1 - 0.0058 15.8 0.6 0.29 10.2 0.1 3.1 4 0 0 4 4 2 1 G-protein alpha subunit Peptidase_S41 PF03572.18 RKP02979.1 - 0.0062 16.1 0.0 0.51 9.9 0.0 2.4 2 0 0 2 2 2 1 Peptidase family S41 ATP-synt_ab PF00006.25 RKP02979.1 - 0.0066 16.1 0.0 4.2 7.0 0.0 3.9 5 0 0 5 5 4 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 RKP02979.1 - 0.013 15.3 0.6 8.9 6.0 0.0 4.1 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 RKP02979.1 - 0.017 14.6 4.7 7 6.1 0.0 4.8 6 0 0 6 6 4 0 PhoH-like protein Septin PF00735.18 RKP02979.1 - 0.041 13.2 1.8 13 5.0 0.1 4.0 5 0 0 5 5 4 0 Septin Rad51 PF08423.11 RKP02979.1 - 0.047 13.0 2.8 0.057 12.7 0.0 2.5 3 0 0 3 3 2 0 Rad51 DUF927 PF06048.11 RKP02979.1 - 0.062 12.9 0.1 4 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF927) SMC_N PF02463.19 RKP02979.1 - 0.066 12.6 0.0 3.9 6.9 0.0 3.1 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain DUF2075 PF09848.9 RKP02979.1 - 0.086 12.1 1.0 25 4.0 0.0 4.2 5 0 0 5 5 4 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 RKP02979.1 - 0.089 12.6 1.0 36 4.1 0.0 4.4 5 0 0 5 5 4 0 Bacterial dnaA protein UvrD-helicase PF00580.21 RKP02979.1 - 0.091 12.3 0.2 24 4.3 0.0 3.3 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Cytidylate_kin PF02224.18 RKP02979.1 - 0.11 12.2 5.5 29 4.3 0.0 5.3 6 0 0 6 6 5 0 Cytidylate kinase DUF87 PF01935.17 RKP02979.1 - 0.11 12.5 2.2 5.5 7.0 0.0 4.1 5 0 0 5 5 3 0 Helicase HerA, central domain Parvo_NS1 PF01057.17 RKP02979.1 - 0.12 11.4 0.1 12 4.9 0.0 3.1 4 0 0 4 4 3 0 Parvovirus non-structural protein NS1 TrwB_AAD_bind PF10412.9 RKP02979.1 - 0.13 11.1 3.6 4.1 6.2 0.2 4.2 5 0 0 5 5 5 0 Type IV secretion-system coupling protein DNA-binding domain Guanylate_kin PF00625.21 RKP02979.1 - 0.15 11.8 0.1 30 4.2 0.0 3.5 3 0 0 3 3 3 0 Guanylate kinase Microtub_bd PF16796.5 RKP02979.1 - 0.16 11.9 0.0 7.2 6.5 0.1 3.1 3 0 0 3 3 3 0 Microtubule binding Thymidylate_kin PF02223.17 RKP02979.1 - 1.5 8.5 2.9 46 3.6 0.0 4.2 5 0 0 5 5 4 0 Thymidylate kinase AAA_17 PF13207.6 RKP02979.1 - 3.1 8.2 9.8 20 5.6 0.0 5.2 6 0 0 6 6 4 0 AAA domain BPL_N PF09825.9 RKP02980.1 - 5.9e-59 200.0 0.0 9e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 RKP02980.1 - 4.7e-20 71.8 0.0 8.4e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 RKP02980.1 - 2.7e-07 30.4 0.1 5.3e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain zf-rbx1 PF12678.7 RKP02981.1 - 2.2e-12 47.1 4.1 4.2e-12 46.2 4.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RKP02981.1 - 3.7e-11 43.2 4.6 6.9e-11 42.3 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 RKP02981.1 - 1.5e-07 31.3 2.1 2.9e-07 30.4 2.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RKP02981.1 - 7.6e-07 28.9 4.7 7.6e-07 28.9 4.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 RKP02981.1 - 1.6e-05 24.9 3.1 4.8e-05 23.3 3.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 RKP02981.1 - 0.00022 21.1 3.6 0.00045 20.1 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RKP02981.1 - 0.00023 20.9 9.6 0.00057 19.7 9.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKP02981.1 - 0.0006 19.6 6.8 0.0058 16.5 7.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKP02981.1 - 0.0012 18.5 2.9 0.0031 17.2 2.9 1.7 1 1 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 RKP02981.1 - 0.0023 17.8 3.3 0.0049 16.7 3.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RKP02981.1 - 0.0056 16.3 2.8 0.0056 16.3 2.8 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 RKP02981.1 - 0.017 15.3 1.0 0.017 15.3 1.0 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 RKP02981.1 - 0.029 14.5 1.6 0.067 13.4 1.6 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 RKP02981.1 - 0.12 12.7 2.0 0.25 11.7 2.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 RKP02981.1 - 0.41 10.6 2.0 0.84 9.6 2.0 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon AAA_6 PF12774.7 RKP02984.1 - 3.6e-157 522.5 0.0 4.4e-155 515.6 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKP02984.1 - 1.5e-134 449.1 0.8 5.7e-134 447.2 0.8 2.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKP02984.1 - 1.3e-109 366.2 0.0 3.8e-109 364.6 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKP02984.1 - 5.5e-100 334.0 3.4 2.1e-99 332.1 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKP02984.1 - 2.3e-83 278.7 0.8 2.3e-83 278.7 0.8 3.5 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKP02984.1 - 3.4e-71 238.5 0.1 1.3e-68 230.0 0.0 3.4 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKP02984.1 - 2.1e-54 183.8 0.0 6.2e-54 182.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RKP02984.1 - 2e-48 165.2 7.6 4.1e-48 164.2 7.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RKP02984.1 - 2.2e-44 150.3 0.1 1.6e-43 147.6 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKP02984.1 - 1.1e-22 80.5 0.0 4.1e-07 30.1 0.0 6.8 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKP02984.1 - 1.6e-19 70.3 0.0 5.4e-18 65.3 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKP02984.1 - 1.3e-13 51.0 0.0 5.1e-13 49.1 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 RKP02984.1 - 1.1e-09 38.9 0.5 0.0018 18.7 0.0 4.8 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP02984.1 - 1.5e-07 31.9 0.0 0.099 13.0 0.0 5.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 RKP02984.1 - 6.1e-07 29.8 8.5 0.00027 21.2 0.0 6.2 7 0 0 7 7 6 1 AAA domain T2SSE PF00437.20 RKP02984.1 - 0.00092 18.3 0.4 0.008 15.3 0.1 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein DHR10 PF18595.1 RKP02984.1 - 0.0023 18.0 5.4 0.0023 18.0 5.4 4.1 4 0 0 4 4 2 1 Designed helical repeat protein 10 domain RNA_helicase PF00910.22 RKP02984.1 - 0.0055 17.1 0.1 4.3 7.8 0.0 4.0 4 0 0 4 4 4 1 RNA helicase DUF815 PF05673.13 RKP02984.1 - 0.0056 15.9 0.0 0.3 10.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 RKP02984.1 - 0.014 15.7 2.3 0.89 9.9 0.0 3.6 4 0 0 4 4 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RKP02984.1 - 0.015 14.6 0.8 1.2 8.5 0.0 3.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.6 RKP02984.1 - 0.017 14.8 6.2 0.73 9.5 0.2 3.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 RKP02984.1 - 0.15 11.8 0.1 21 4.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 RKP02984.1 - 0.15 11.8 0.9 0.9 9.3 0.1 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain PEARLI-4 PF05278.12 RKP02984.1 - 0.18 11.4 5.5 0.52 9.8 5.5 1.8 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Mg_chelatase PF01078.21 RKP02984.1 - 0.2 11.0 3.5 22 4.3 0.0 3.9 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI Sec34 PF04136.15 RKP02984.1 - 0.59 10.0 9.0 17 5.2 1.1 4.4 3 1 1 4 4 3 0 Sec34-like family DivIC PF04977.15 RKP02984.1 - 0.61 9.9 6.3 0.71 9.7 1.4 3.2 2 0 0 2 2 2 0 Septum formation initiator Vps5 PF09325.10 RKP02984.1 - 9.5 5.7 10.1 5.2 6.5 3.6 2.6 2 0 0 2 2 2 0 Vps5 C terminal like DUF4477 PF14780.6 RKP02985.1 - 8.4e-14 51.6 0.3 2.3e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) FTHFS PF01268.19 RKP02986.1 - 2.1e-255 848.2 0.4 3.2e-255 847.6 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 RKP02986.1 - 1.6e-65 219.3 1.1 1.6e-65 219.3 1.1 2.4 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 RKP02986.1 - 1.1e-36 125.7 0.2 2.6e-36 124.4 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Pkinase PF00069.25 RKP02987.1 - 3.9e-63 213.3 0.0 4.9e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02987.1 - 4.6e-39 134.3 0.0 5.9e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP02987.1 - 9.2e-06 25.2 0.0 2.8e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 RKP02987.1 - 0.0058 16.6 0.5 0.19 11.6 0.4 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP02987.1 - 0.015 14.2 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 RKP02987.1 - 0.028 13.5 0.1 0.069 12.2 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 RKP02987.1 - 0.035 12.9 0.0 0.068 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase CDC27 PF09507.10 RKP02988.1 - 1.6e-26 93.7 24.4 1.2e-24 87.5 24.4 2.2 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 ZZ PF00569.17 RKP02990.1 - 6.5e-12 45.1 8.1 1.4e-11 44.0 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 RKP02990.1 - 1.1e-10 41.7 0.1 3.3e-10 40.1 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 RKP02990.1 - 4.6e-09 36.3 0.0 1.5e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKP02990.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain C1_2 PF03107.16 RKP02990.1 - 0.087 13.1 8.1 0.17 12.3 8.1 1.5 1 0 0 1 1 1 0 C1 domain DUF4200 PF13863.6 RKP02991.1 - 3.8e-33 114.4 20.5 3.8e-33 114.4 20.5 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) DUF5082 PF16888.5 RKP02991.1 - 0.049 13.9 0.2 0.049 13.9 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) TP_methylase PF00590.20 RKP02991.1 - 0.09 12.7 0.1 0.09 12.7 0.1 2.4 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Baculo_PEP_C PF04513.12 RKP02991.1 - 0.15 12.1 10.0 3.1 7.8 5.4 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 RKP02991.1 - 5.8 7.5 28.7 1.1 9.7 3.0 3.7 2 2 1 3 3 3 0 Protein of unknown function DUF16 TFIIS_C PF01096.18 RKP02992.1 - 2e-16 59.5 0.9 2e-16 59.5 0.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 RKP02992.1 - 4.2e-06 26.5 6.5 0.0001 22.1 1.0 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 RKP02992.1 - 0.0067 16.4 0.8 0.0067 16.4 0.8 2.8 3 0 0 3 3 3 1 Ogr/Delta-like zinc finger DZR PF12773.7 RKP02992.1 - 0.0097 15.9 12.1 0.17 11.9 1.4 2.9 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 RKP02992.1 - 0.022 14.3 0.6 0.022 14.3 0.6 2.9 2 2 0 2 2 2 0 TFIIB zinc-binding Baculo_LEF5_C PF11792.8 RKP02992.1 - 0.023 14.4 0.1 0.086 12.5 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Trm112p PF03966.16 RKP02992.1 - 0.026 15.1 0.5 0.21 12.2 0.5 2.5 1 1 0 1 1 1 0 Trm112p-like protein Lar_restr_allev PF14354.6 RKP02992.1 - 0.033 14.6 0.8 0.033 14.6 0.8 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar eIF-5_eIF-2B PF01873.17 RKP02992.1 - 0.053 13.4 0.8 0.053 13.4 0.8 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DNA_RNApol_7kD PF03604.13 RKP02992.1 - 0.11 12.2 8.1 9.1 6.1 0.1 3.9 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit MqsA_antitoxin PF15731.5 RKP02992.1 - 0.14 12.3 1.0 0.29 11.2 0.3 1.8 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Elf1 PF05129.13 RKP02992.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_S27e PF01667.17 RKP02992.1 - 0.18 11.6 20.2 1 9.1 2.9 3.9 2 2 1 3 3 3 0 Ribosomal protein S27 Mu-like_Com PF10122.9 RKP02992.1 - 0.18 11.3 9.4 1 8.9 0.2 3.6 3 1 1 4 4 4 0 Mu-like prophage protein Com GFA PF04828.14 RKP02992.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.13 RKP02992.1 - 0.24 11.2 12.6 0.38 10.5 0.2 3.0 2 1 0 2 2 2 0 CSL zinc finger HypA PF01155.19 RKP02992.1 - 0.24 11.4 11.1 0.86 9.7 1.8 3.0 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 RKP02992.1 - 0.38 10.7 16.3 1.8 8.6 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_7 PF02591.15 RKP02992.1 - 0.4 10.9 7.1 7.4 6.9 0.1 3.7 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-HYPF PF07503.12 RKP02992.1 - 0.69 9.7 0.1 0.69 9.7 0.1 3.4 4 0 0 4 4 3 0 HypF finger zinc_ribbon_2 PF13240.6 RKP02992.1 - 0.92 9.3 16.8 1.4 8.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain DUF35_N PF12172.8 RKP02992.1 - 0.92 9.4 10.1 16 5.5 0.0 3.8 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.6 RKP02992.1 - 0.94 9.0 17.6 0.56 9.7 0.8 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 RKP02992.1 - 1.5 8.9 10.4 4.9 7.2 0.9 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_3 PF13878.6 RKP02992.1 - 1.7 8.6 12.0 1.6 8.6 0.1 3.9 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO OrfB_Zn_ribbon PF07282.11 RKP02992.1 - 2.4 8.2 8.4 3.6 7.6 0.2 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.6 RKP02992.1 - 2.5 8.8 10.0 3.4 8.4 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 RKP02992.1 - 2.5 8.3 16.5 1.8 8.7 0.1 4.0 3 1 1 4 4 3 0 Zinc ribbon domain zf_UBZ PF18439.1 RKP02992.1 - 5.7 6.6 14.5 7.8 6.2 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 RKP02992.1 - 9.8 6.0 10.7 2 8.2 0.5 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type SET PF00856.28 RKP02993.1 - 2.2e-10 41.2 0.1 3.9e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 SET domain MAPKK1_Int PF08923.10 RKP02995.1 - 4.4e-08 33.0 0.0 7.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Spt20 PF12090.8 RKP02996.1 - 3.3e-06 26.9 54.8 3.8e-05 23.4 0.0 5.7 4 1 0 4 4 4 3 Spt20 family Gti1_Pac2 PF09729.9 RKP02996.1 - 0.79 9.8 4.3 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Pkinase PF00069.25 RKP02997.1 - 1.8e-36 125.9 0.0 5e-36 124.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP02997.1 - 3e-18 66.0 0.0 5.7e-18 65.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP02997.1 - 0.013 14.3 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 RKP02997.1 - 0.33 9.9 0.0 0.46 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Rgp1 PF08737.10 RKP02998.1 - 8.2e-55 186.6 0.0 4.3e-27 95.4 0.0 2.7 3 0 0 3 3 3 2 Rgp1 Arrestin_N PF00339.29 RKP02998.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain NOA36 PF06524.12 RKP02998.1 - 0.075 12.3 0.4 0.11 11.8 0.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3246 PF11596.8 RKP02998.1 - 0.077 12.4 1.1 0.17 11.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 RKP02998.1 - 4 7.1 6.9 6.7 6.4 6.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Endosulfine PF04667.17 RKP02999.1 - 1.6e-18 66.6 0.6 2.4e-18 66.0 0.4 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Mo25 PF08569.11 RKP03002.1 - 2.5e-137 457.6 8.9 2.8e-137 457.5 8.9 1.0 1 0 0 1 1 1 1 Mo25-like Hus1 PF04005.12 RKP03004.1 - 1.1e-36 126.5 0.0 1.2e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein ATG_C PF09333.11 RKP03004.1 - 0.051 13.9 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Snf7 PF03357.21 RKP03005.1 - 1.1 8.9 9.6 0.34 10.5 3.6 2.4 2 1 0 2 2 2 0 Snf7 ERM PF00769.19 RKP03005.1 - 2.1 8.1 8.4 3.4 7.4 8.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FHA PF00498.26 RKP03006.1 - 3.5e-16 59.3 0.0 5.3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 RKP03006.1 - 9.5e-13 47.6 9.1 1.8e-12 46.7 9.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 RKP03006.1 - 3.5e-09 36.9 9.1 5.2e-09 36.3 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RKP03006.1 - 2e-05 24.4 8.8 3e-05 23.8 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 RKP03006.1 - 5.3e-05 23.5 0.0 8.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 RKP03006.1 - 0.00017 21.5 11.1 0.00027 20.9 11.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RKP03006.1 - 0.00031 20.7 4.1 0.00049 20.1 4.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RKP03006.1 - 0.00074 19.5 9.5 0.0013 18.7 9.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 RKP03006.1 - 0.00079 19.3 5.7 0.0012 18.7 5.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 RKP03006.1 - 0.00082 19.6 7.7 0.0016 18.7 7.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RKP03006.1 - 0.0014 18.4 11.1 0.0024 17.7 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zip PF02535.22 RKP03007.1 - 1.1e-27 97.1 0.7 2e-27 96.3 0.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter LRR_8 PF13855.6 RKP03007.1 - 1.2e-14 53.8 0.1 3.6e-08 33.0 0.0 2.6 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RKP03007.1 - 2.2e-08 34.2 0.0 0.011 16.2 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP03007.1 - 0.0046 17.3 0.0 15 6.6 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 RKP03007.1 - 0.14 12.3 5.1 4.2 7.7 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Cwf_Cwc_15 PF04889.12 RKP03007.1 - 1.3 8.7 8.5 0.46 10.2 0.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PLDc_2 PF13091.6 RKP03009.1 - 3.7e-16 59.2 0.0 3.2e-05 23.8 0.0 3.9 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.22 RKP03009.1 - 3.7e-13 49.1 0.7 1.7e-06 28.0 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif RabGAP-TBC PF00566.18 RKP03010.1 - 1.5e-20 73.8 0.0 2.8e-20 72.9 0.0 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RskA PF10099.9 RKP03010.1 - 0.00063 20.1 13.2 0.00063 20.1 13.2 5.4 3 2 2 5 5 5 1 Anti-sigma-K factor rskA RraA-like PF03737.15 RKP03011.1 - 5.6e-24 85.0 0.1 7.7e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Tyr-DNA_phospho PF06087.12 RKP03012.1 - 2.8e-105 352.7 0.0 3.6e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase CPP1-like PF11833.8 RKP03013.1 - 4.4 6.9 6.8 0.35 10.5 1.6 1.9 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4667 PF15700.5 RKP03014.1 - 0.00015 22.0 2.6 0.00034 20.8 2.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SR-25 PF10500.9 RKP03014.1 - 0.8 9.3 18.6 1.6 8.3 18.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 RKP03014.1 - 2.4 8.0 6.5 3.4 7.5 6.5 1.2 1 0 0 1 1 1 0 SPX domain Spt5-NGN PF03439.13 RKP03015.1 - 6.8e-24 83.6 0.1 1.3e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 RKP03015.1 - 5.7e-10 40.1 14.6 5.7e-10 40.1 14.6 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 RKP03015.1 - 1.6e-05 25.4 27.0 1.6e-05 25.4 27.0 3.5 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 RKP03015.1 - 2.8e-05 23.9 11.1 0.00098 19.0 2.8 4.5 5 0 0 5 5 5 2 KOW motif PGA2 PF07543.12 RKP03015.1 - 4.3 7.3 26.7 0.46 10.5 21.9 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 2-oxoacid_dh PF00198.23 RKP03016.1 - 2.7e-80 269.2 0.0 3.6e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RKP03016.1 - 6.7e-17 61.1 0.2 1.8e-16 59.7 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RKP03016.1 - 7.4e-15 55.0 1.0 2.7e-14 53.2 1.0 2.1 1 0 0 1 1 1 1 e3 binding domain Apt1 PF10351.9 RKP03016.1 - 0.16 10.8 0.9 0.17 10.7 0.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF908 PF06012.12 RKP03016.1 - 0.8 9.1 8.7 1.2 8.5 8.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MAGE_N PF12440.8 RKP03016.1 - 0.97 10.1 24.5 2.5 8.8 3.5 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal CCDC106 PF15794.5 RKP03016.1 - 1 9.0 3.2 1.7 8.3 3.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ndc1_Nup PF09531.10 RKP03016.1 - 3.5 6.2 4.9 5.6 5.5 4.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1805 PF08827.11 RKP03017.1 - 0.035 14.4 0.6 0.084 13.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RE_AspBHI_N PF18062.1 RKP03017.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal Perilipin PF03036.16 RKP03017.1 - 0.16 11.0 1.4 0.23 10.4 1.4 1.1 1 0 0 1 1 1 0 Perilipin family AMP-binding PF00501.28 RKP03018.1 - 4.9e-80 269.2 0.0 6.3e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKP03018.1 - 1.2e-14 55.0 0.8 8.6e-14 52.3 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abp2 PF09441.10 RKP03019.1 - 0.00022 21.3 0.1 0.00022 21.3 0.1 2.1 2 0 0 2 2 2 1 ARS binding protein 2 Tub PF01167.18 RKP03020.1 - 2.3e-38 132.3 0.0 2.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 RKP03020.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF2533 PF10752.9 RKP03020.1 - 0.16 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Skp1 PF01466.19 RKP03021.1 - 1.1e-27 95.8 1.0 2e-27 95.1 1.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RKP03021.1 - 1.6e-23 82.6 0.1 4.3e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.6 RKP03021.1 - 0.028 14.7 0.4 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Lung_7-TM_R PF06814.13 RKP03022.1 - 1.3e-49 169.0 13.1 1.5e-49 168.9 13.1 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor E1-E2_ATPase PF00122.20 RKP03023.1 - 2.6e-46 157.4 7.7 2.6e-46 157.4 7.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RKP03023.1 - 2.8e-35 121.7 6.1 2.8e-35 121.7 6.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RKP03023.1 - 1.8e-24 87.2 1.0 1.6e-23 84.1 1.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP03023.1 - 1.4e-15 57.2 0.0 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RKP03023.1 - 1.4e-13 50.3 0.0 3.6e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKP03023.1 - 2e-06 27.7 1.6 0.00011 22.1 1.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RKP03023.1 - 0.015 15.8 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 RKP03023.1 - 0.27 10.0 0.0 0.27 10.0 0.0 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) PilX_N PF14341.6 RKP03023.1 - 0.86 9.6 3.6 22 5.1 0.9 3.5 2 0 0 2 2 2 0 PilX N-terminal Acetyltransf_1 PF00583.25 RKP03024.1 - 7.9e-18 64.8 0.0 9.5e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKP03024.1 - 8e-11 42.2 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKP03024.1 - 1.6e-10 40.8 0.1 2.5e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RKP03024.1 - 1.9e-10 40.8 0.0 2.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RKP03024.1 - 6e-08 32.8 0.0 7.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RKP03024.1 - 5.4e-06 26.2 0.0 7.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RKP03024.1 - 6.5e-06 26.9 0.0 7.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 RKP03024.1 - 0.0008 19.6 0.1 0.0012 19.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RKP03024.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RKP03024.1 - 0.028 14.5 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RRM_1 PF00076.22 RKP03025.1 - 9.6e-21 73.4 0.0 7.4e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKP03025.1 - 7.6e-09 35.2 0.0 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKP03025.1 - 0.0093 15.8 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4440 PF14534.6 RKP03025.1 - 0.012 16.0 0.0 0.61 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Pex2_Pex12 PF04757.14 RKP03026.1 - 1.2e-25 90.5 0.5 1.5e-25 90.2 0.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RKP03026.1 - 0.00041 20.2 0.4 0.00061 19.6 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP03026.1 - 0.00078 19.2 3.9 0.002 17.9 3.7 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKP03026.1 - 0.0037 17.6 1.1 0.0072 16.6 1.1 1.5 1 0 0 1 1 1 1 Ring finger domain DZR PF12773.7 RKP03026.1 - 0.0068 16.4 0.6 0.012 15.6 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4 PF00097.25 RKP03026.1 - 0.02 14.7 0.5 0.034 14.0 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKP03026.1 - 0.096 12.9 2.1 0.21 11.8 2.1 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Lar_restr_allev PF14354.6 RKP03026.1 - 0.21 12.0 1.7 0.39 11.1 1.7 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-RING_UBOX PF13445.6 RKP03026.1 - 0.35 10.9 4.3 0.61 10.2 4.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Motile_Sperm PF00635.26 RKP03027.1 - 2.6e-16 59.4 0.0 4.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF4366 PF14283.6 RKP03027.1 - 0.26 11.3 0.0 0.26 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Mog1 PF04603.12 RKP03028.1 - 3.5e-32 111.6 0.0 4.7e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Evr1_Alr PF04777.13 RKP03029.1 - 2.8e-26 91.9 0.1 3.1e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Erv1 / Alr family SNAD4 PF18750.1 RKP03029.1 - 0.041 14.0 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 RKP03029.1 - 0.079 13.2 0.1 0.16 12.2 0.0 1.6 1 1 1 2 2 2 0 APOBEC1 THF_DHG_CYH PF00763.23 RKP03030.1 - 5.2e-20 71.8 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 RKP03030.1 - 5.4e-14 51.8 0.1 1.1e-10 41.1 0.0 3.0 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1368 PF07112.11 RKP03030.1 - 0.075 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) MMS19_N PF14500.6 RKP03031.1 - 1.1e-67 228.3 0.0 3.5e-66 223.5 0.0 2.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 RKP03031.1 - 2.9e-44 151.9 0.3 9.7e-44 150.1 0.0 2.1 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 RKP03031.1 - 0.0015 19.0 1.2 0.0015 19.0 1.2 6.9 5 2 1 6 6 6 1 HEAT-like repeat MaAIMP_sms PF16951.5 RKP03031.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit Brix PF04427.18 RKP03032.1 - 2.8e-28 99.4 0.0 3.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Paf1 PF03985.13 RKP03032.1 - 0.018 14.1 4.3 0.029 13.4 4.3 1.2 1 0 0 1 1 1 0 Paf1 SH3_9 PF14604.6 RKP03033.1 - 2e-28 98.0 3.4 2.3e-13 49.8 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 RKP03033.1 - 3.1e-27 93.9 1.2 1.5e-13 50.1 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 RKP03033.1 - 1.2e-21 76.2 0.0 2.4e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 RKP03033.1 - 4.4e-19 68.5 0.0 8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.9 RKP03033.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme TFIIA PF03153.13 RKP03033.1 - 0.2 11.6 20.3 0.29 11.1 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1752 PF08550.10 RKP03034.1 - 0.18 11.7 3.2 0.62 10.0 3.2 2.0 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Nipped-B_C PF12830.7 RKP03035.1 - 9.2e-33 113.8 0.0 3.4e-32 111.9 0.0 2.1 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 RKP03035.1 - 1.2e-06 28.7 7.5 1.9e-06 28.1 1.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 RKP03035.1 - 3.3e-05 23.2 0.7 0.0052 16.0 0.1 2.8 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 RKP03035.1 - 0.0081 14.8 1.3 0.048 12.2 0.1 2.6 3 0 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 RKP03035.1 - 0.035 14.1 0.3 21 5.1 0.1 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RKP03035.1 - 0.045 14.0 15.3 13 6.4 0.0 6.9 7 0 0 7 7 7 0 HEAT repeat HEAT_2 PF13646.6 RKP03035.1 - 0.16 12.3 7.9 3 8.3 0.3 5.3 5 0 0 5 5 5 0 HEAT repeats FTP PF07504.13 RKP03035.1 - 0.2 11.5 0.1 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif DAGK_cat PF00781.24 RKP03036.1 - 1.4e-24 86.1 0.0 2.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LRR_4 PF12799.7 RKP03037.1 - 7.6e-12 45.3 0.0 0.00011 22.5 0.1 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP03037.1 - 1.7e-06 27.7 2.6 0.00036 20.2 0.2 4.3 5 1 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.6 RKP03037.1 - 0.00013 21.8 0.1 6.7 7.0 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 RKP03037.1 - 0.0011 19.2 0.1 1.1e+02 3.9 0.1 5.5 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 RKP03037.1 - 0.0024 17.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Leucine-rich repeat PHD PF00628.29 RKP03038.1 - 1.1e-08 34.8 3.5 1.1e-08 34.8 3.5 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 RKP03038.1 - 3.8e-05 23.1 2.2 8.1e-05 22.1 2.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 RKP03038.1 - 6.2e-05 22.8 2.0 0.00016 21.5 2.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Linker_histone PF00538.19 RKP03038.1 - 0.0032 17.8 0.0 0.0059 16.9 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family zf-PHD-like PF15446.6 RKP03038.1 - 0.32 10.6 0.5 0.63 9.7 0.5 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 RKP03038.1 - 1.1 9.2 5.3 0.12 12.3 0.4 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps51 PF08700.11 RKP03039.1 - 2.2e-11 43.7 0.0 5.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 DUF1179 PF06678.11 RKP03040.1 - 0.21 11.6 1.0 0.79 9.7 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Utp14 PF04615.13 RKP03041.1 - 1.5e-131 440.5 32.2 1.5e-131 440.5 32.2 2.9 1 1 1 3 3 3 1 Utp14 protein SET PF00856.28 RKP03042.1 - 4.4e-09 36.9 0.1 1.2e-08 35.5 0.2 1.6 1 1 1 2 2 2 1 SET domain LMBR1 PF04791.16 RKP03043.1 - 3.7e-89 300.0 5.4 4.9e-89 299.6 5.4 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein MCU PF04678.13 RKP03044.1 - 8.8e-35 120.4 0.4 1.4e-34 119.7 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2244 PF10003.9 RKP03044.1 - 0.0043 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) DUF1640 PF07798.11 RKP03045.1 - 3.5e-35 121.6 4.9 3.9e-35 121.5 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) JAKMIP_CC3 PF16034.5 RKP03045.1 - 0.062 13.2 2.3 0.086 12.8 2.3 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF1045 PF06299.12 RKP03045.1 - 0.078 12.9 4.7 0.081 12.9 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1045) Lectin_N PF03954.14 RKP03045.1 - 0.1 12.4 0.7 1.8 8.3 0.1 2.3 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF883 PF05957.13 RKP03045.1 - 3.1 8.5 12.2 0.63 10.7 6.2 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) CoA_binding PF02629.19 RKP03046.1 - 3.9e-31 107.6 0.8 1.7e-30 105.5 0.8 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 RKP03046.1 - 1.1e-23 83.7 0.1 2.1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 RKP03046.1 - 3.1e-09 36.8 0.0 7.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 RKP03046.1 - 4.4e-05 24.0 0.3 0.0002 21.8 0.1 2.2 4 0 0 4 4 4 1 CoA binding domain Glyco_trans_1_4 PF13692.6 RKP03046.1 - 0.00063 20.2 0.7 1.4 9.4 0.2 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 GDC-P PF02347.16 RKP03047.1 - 8.5e-186 617.9 0.0 2.2e-178 593.5 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 RKP03047.1 - 0.00025 20.4 0.2 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Beta-eliminating lyase BCNT PF07572.12 RKP03048.1 - 2.1e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development YL1 PF05764.13 RKP03048.1 - 0.0077 16.4 1.0 0.0077 16.4 1.0 1.8 2 0 0 2 2 2 1 YL1 nuclear protein Nop14 PF04147.12 RKP03048.1 - 4.3 5.4 8.1 5.9 5.0 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4203 PF13886.6 RKP03049.1 - 2.8e-38 131.6 35.0 4.5e-38 131.0 35.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) RasGEF PF00617.19 RKP03050.1 - 7.1e-44 150.1 0.0 9.8e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain DUF4936 PF16290.5 RKP03050.1 - 0.037 14.7 0.4 0.19 12.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4936) RhoGEF PF00621.20 RKP03051.1 - 1.1e-42 146.3 7.4 1.1e-42 146.3 0.0 2.3 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.28 RKP03051.1 - 9.1e-20 70.0 0.2 3.3e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 RKP03051.1 - 1e-19 70.1 0.2 1.7e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 RKP03051.1 - 3.3e-19 68.7 0.0 5.8e-14 51.9 0.0 3.0 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 RKP03051.1 - 3.6e-17 62.6 0.7 6e-16 58.6 0.0 2.4 2 0 0 2 2 1 1 Pleckstrin homology domain SH3_2 PF07653.17 RKP03051.1 - 5.1e-10 38.9 0.0 2.5e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain TFIIA PF03153.13 RKP03051.1 - 0.0035 17.4 30.4 0.0035 17.4 30.4 5.1 3 1 2 5 5 2 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 RKP03051.1 - 0.0058 16.8 6.0 0.012 15.8 4.2 2.4 2 0 0 2 2 2 1 DDHD domain TERB2 PF15101.6 RKP03051.1 - 0.03 14.4 14.7 0.076 13.1 14.7 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SH3_3 PF08239.11 RKP03051.1 - 0.036 14.4 0.5 8 6.8 0.1 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain SpoIIP PF07454.11 RKP03051.1 - 0.065 12.7 8.6 0.13 11.7 8.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4471 PF14740.6 RKP03051.1 - 0.065 12.5 5.1 0.12 11.6 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) EF-hand_6 PF13405.6 RKP03051.1 - 0.065 13.2 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Serinc PF03348.15 RKP03051.1 - 0.17 10.8 3.5 0.26 10.2 3.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) EPL1 PF10513.9 RKP03051.1 - 0.19 12.1 9.3 0.44 10.9 9.3 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4746 PF15928.5 RKP03051.1 - 0.23 10.9 6.9 0.45 9.9 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EF-hand_7 PF13499.6 RKP03051.1 - 0.24 11.9 0.0 0.58 10.6 0.0 1.7 1 1 0 1 1 1 0 EF-hand domain pair Presenilin PF01080.17 RKP03051.1 - 1.2 7.8 15.2 2.5 6.8 15.2 1.4 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 RKP03051.1 - 1.3 8.6 43.4 3.1 7.3 43.4 1.6 1 0 0 1 1 1 0 Spt20 family SLC12 PF03522.15 RKP03051.1 - 1.6 7.7 10.5 2.6 7.0 10.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 RKP03051.1 - 1.6 8.9 9.1 5.5 7.1 9.1 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EMC3_TMCO1 PF01956.16 RKP03051.1 - 1.7 8.4 9.6 1.3 8.8 7.3 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AAA_23 PF13476.6 RKP03051.1 - 2.9 8.4 13.2 18 5.8 14.0 1.8 2 0 0 2 2 2 0 AAA domain Hid1 PF12722.7 RKP03051.1 - 2.9 5.9 12.2 4.9 5.1 12.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLN3 PF02487.17 RKP03051.1 - 3.8 6.5 8.9 7.5 5.5 8.9 1.4 1 0 0 1 1 1 0 CLN3 protein RR_TM4-6 PF06459.12 RKP03051.1 - 4.1 7.1 12.1 9.4 6.0 12.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NEMP PF10225.9 RKP03051.1 - 4.2 6.9 7.1 8.3 6.0 7.1 1.4 1 0 0 1 1 1 0 NEMP family Paf1 PF03985.13 RKP03051.1 - 5.3 5.9 15.0 9.7 5.1 15.0 1.3 1 0 0 1 1 1 0 Paf1 Paramyxo_ncap PF00973.19 RKP03051.1 - 6.5 5.6 5.8 12 4.7 5.8 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3402 PF11882.8 RKP03051.1 - 6.9 5.7 16.0 12 4.9 16.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Connexin PF00029.19 RKP03051.1 - 7.4 6.3 11.9 12 5.5 11.9 1.2 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 RKP03051.1 - 7.4 5.4 19.5 12 4.7 19.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EOS1 PF12326.8 RKP03051.1 - 8 6.4 8.2 22 4.9 8.2 1.7 1 0 0 1 1 1 0 N-glycosylation protein ORC_WH_C PF18137.1 RKP03051.1 - 9 6.4 15.3 23 5.0 15.3 1.6 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal TMF_DNA_bd PF12329.8 RKP03052.1 - 0.0028 17.6 0.1 0.0046 16.9 0.1 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 RKP03052.1 - 0.076 13.5 1.2 0.14 12.7 1.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2959 PF11172.8 RKP03052.1 - 0.08 13.1 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Spc29 PF17082.5 RKP03052.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 Striatin PF08232.12 RKP03052.1 - 0.11 13.1 0.4 0.31 11.6 0.4 1.8 1 0 0 1 1 1 0 Striatin family SOAR PF16533.5 RKP03052.1 - 0.14 12.2 2.5 0.34 10.9 0.4 2.2 1 1 1 2 2 2 0 STIM1 Orai1-activating region HAUS-augmin3 PF14932.6 RKP03052.1 - 0.39 10.2 1.4 0.56 9.7 1.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Med21 PF11221.8 RKP03052.1 - 0.71 10.1 0.0 0.71 10.1 0.0 3.0 3 1 0 3 3 3 0 Subunit 21 of Mediator complex Thg1 PF04446.12 RKP03053.1 - 2.1e-28 98.9 0.0 2.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase bZIP_1 PF00170.21 RKP03055.1 - 5.2e-07 29.7 3.4 8.7e-07 29.0 3.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor CDH-cyt PF16010.5 RKP03056.1 - 3e-11 43.4 0.7 4.6e-11 42.7 0.7 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 RKP03056.1 - 7.1e-09 35.9 10.7 7.1e-09 35.9 10.7 2.2 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 RKP03056.1 - 8.6e-09 35.7 0.2 1.5e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 DOMON domain DUF3169 PF11368.8 RKP03056.1 - 0.59 9.6 9.0 0.072 12.6 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2427 PF10348.9 RKP03056.1 - 2.9 7.7 14.3 5.1 7.0 9.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4271 PF14093.6 RKP03056.1 - 3.6 7.4 8.9 2.8 7.8 6.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) YqaJ PF09588.10 RKP03057.1 - 5.3e-18 65.6 0.0 1.1e-16 61.4 0.0 2.3 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain TruD PF01142.18 RKP03058.1 - 4.1e-56 190.6 0.0 4.6e-54 183.8 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF1126 PF06565.12 RKP03059.1 - 3.8e-57 190.6 0.0 2.1e-24 85.4 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain TCTP PF00838.17 RKP03062.1 - 1.2e-71 240.4 4.4 1.3e-71 240.3 4.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF1512 PF07431.12 RKP03062.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) PseudoU_synth_1 PF01416.20 RKP03063.1 - 0.003 18.0 0.0 0.012 16.1 0.0 2.1 1 1 0 1 1 1 1 tRNA pseudouridine synthase DUF4680 PF15730.5 RKP03063.1 - 2.4 8.5 6.4 11 6.3 6.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) zf-C3HC4_2 PF13923.6 RKP03064.1 - 4.8e-08 32.7 15.9 8.7e-08 31.9 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKP03064.1 - 4.3e-06 27.0 15.6 8.1e-06 26.1 15.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RKP03064.1 - 4.7e-06 26.4 15.9 8.7e-06 25.5 15.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP03064.1 - 1.1e-05 25.3 14.4 3.3e-05 23.8 14.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RKP03064.1 - 6.4e-05 22.7 13.1 0.00013 21.8 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP03064.1 - 0.00063 19.7 15.3 0.0013 18.7 15.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 RKP03064.1 - 0.00091 19.1 9.0 0.0016 18.3 9.0 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 RKP03064.1 - 0.015 15.5 11.7 0.038 14.3 11.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 RKP03064.1 - 0.021 15.0 16.3 0.021 15.0 16.3 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF2778 PF10908.8 RKP03064.1 - 0.15 12.3 0.6 0.28 11.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) Prok-RING_4 PF14447.6 RKP03064.1 - 0.26 11.2 12.8 0.68 9.8 12.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 RKP03064.1 - 1.9 8.7 10.0 3.4 7.9 10.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Cofilin_ADF PF00241.20 RKP03066.1 - 5.4e-17 61.7 0.0 9.5e-17 60.9 0.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lar_N PF09861.9 RKP03066.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Methyltr_RsmB-F PF01189.17 RKP03067.1 - 3.3e-70 235.8 0.0 5.7e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 RKP03067.1 - 7.8e-12 45.5 0.0 1.6e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 RKP03067.1 - 0.00022 21.4 0.1 0.00042 20.5 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 RKP03067.1 - 0.0022 17.8 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DDHD PF02862.17 RKP03067.1 - 0.21 11.7 2.5 0.4 10.8 2.5 1.5 1 0 0 1 1 1 0 DDHD domain TRAPPC-Trs85 PF12739.7 RKP03067.1 - 1.6 7.6 8.3 3.3 6.6 8.3 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Presenilin PF01080.17 RKP03067.1 - 1.8 7.2 11.5 2.5 6.8 11.5 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 RKP03067.1 - 6.6 5.1 6.5 9.4 4.6 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 NDK PF00334.19 RKP03068.1 - 5.9e-38 129.9 0.0 6.5e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase BAR PF03114.18 RKP03069.1 - 6.9e-46 156.8 11.3 7.7e-46 156.7 11.3 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RKP03069.1 - 2.7e-07 30.6 7.4 3.4e-07 30.2 7.4 1.3 1 1 0 1 1 1 1 BAR domain of APPL family Syntaxin_2 PF14523.6 RKP03069.1 - 0.03 14.7 6.0 0.49 10.8 3.3 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Tn7_Tnp_TnsA_C PF08721.11 RKP03069.1 - 0.88 10.3 3.9 1.9 9.2 0.3 2.7 2 1 2 4 4 4 0 TnsA endonuclease C terminal FeoB_Cyto PF17910.1 RKP03069.1 - 1.7 9.2 7.0 1.6 9.3 5.0 2.0 1 1 1 2 2 2 0 FeoB cytosolic helical domain Sensor PF13796.6 RKP03070.1 - 0.014 15.4 12.1 0.062 13.4 12.1 2.0 1 0 0 1 1 1 0 Putative sensor Phage_holin_3_6 PF07332.11 RKP03070.1 - 2.5 8.2 9.9 6.1 6.9 9.9 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 RKP03072.1 - 8.7e-20 70.7 8.9 0.0012 19.6 0.3 6.0 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03072.1 - 2.6e-09 37.2 0.4 0.0085 16.4 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP03072.1 - 0.00077 18.5 0.0 2.2 7.1 0.0 3.3 2 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L6 PF00347.23 RKP03073.1 - 3.3e-12 46.9 0.0 0.00013 22.6 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L6 Shadoo PF14999.6 RKP03073.1 - 0.0066 16.5 3.0 0.012 15.7 3.0 1.5 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective SRF-TF PF00319.18 RKP03074.1 - 7.2e-20 70.2 0.0 9.6e-20 69.8 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tmemb_14 PF03647.13 RKP03075.1 - 0.0018 19.0 0.2 0.0037 18.0 0.2 1.5 1 0 0 1 1 1 1 Transmembrane proteins 14C ABC_membrane PF00664.23 RKP03075.1 - 0.011 15.5 3.2 0.017 14.8 3.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Trypan_PARP PF05887.11 RKP03075.1 - 0.27 11.2 11.3 0.53 10.3 11.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tom5 PF10642.9 RKP03075.1 - 4.2 7.5 8.4 0.41 10.7 0.3 3.1 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase Cation_efflux PF01545.21 RKP03076.1 - 6.2e-44 150.1 12.9 7.4e-44 149.9 12.9 1.1 1 0 0 1 1 1 1 Cation efflux family CBP_BcsR PF10945.8 RKP03076.1 - 0.1 12.1 0.6 30 4.2 0.1 3.3 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR Adenylsucc_synt PF00709.21 RKP03077.1 - 4.3e-173 576.1 0.0 4.9e-173 575.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase SPC25 PF06703.11 RKP03078.1 - 3.9e-22 78.8 0.1 4.7e-21 75.3 0.1 2.0 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) SNF5 PF04855.12 RKP03080.1 - 8.8e-23 81.3 0.1 8.8e-23 81.3 0.1 1.0 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 RPAP3_C PF13877.6 RKP03081.1 - 2.7e-13 50.2 0.0 5.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 RKP03081.1 - 4.2e-11 42.1 0.4 0.00059 19.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03081.1 - 6.6e-11 41.6 0.0 3.9e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKP03081.1 - 1.5e-08 35.1 14.7 2.8e-08 34.3 0.2 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP03081.1 - 3.3e-07 30.4 9.0 0.00054 20.1 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03081.1 - 0.00011 21.8 0.0 0.0046 16.6 0.0 3.0 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 RKP03081.1 - 0.00036 21.0 3.7 0.0073 16.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP03081.1 - 0.001 18.9 0.5 0.023 14.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03081.1 - 0.0012 18.9 0.0 0.045 14.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03081.1 - 0.0046 17.5 1.3 13 6.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP03081.1 - 0.023 14.9 0.5 0.052 13.8 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKP03081.1 - 0.043 14.6 7.4 2.3 9.3 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03081.1 - 0.079 13.4 3.0 1.3 9.6 0.1 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat ATE_C PF04377.15 RKP03082.1 - 4.6e-47 160.0 0.8 6.4e-47 159.5 0.8 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 RKP03082.1 - 3.1e-24 85.2 3.6 6e-24 84.2 2.3 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Vps26 PF03643.15 RKP03083.1 - 6.5e-111 369.7 1.0 7.9e-111 369.5 1.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 RKP03083.1 - 0.02 15.0 0.1 0.21 11.7 0.0 2.2 1 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Actin PF00022.19 RKP03084.1 - 1.9e-08 33.3 0.0 1.7e-06 26.9 0.0 2.0 1 1 1 2 2 2 2 Actin Coilin_N PF15862.5 RKP03085.1 - 0.0016 18.3 6.8 0.0016 18.3 6.8 1.1 1 0 0 1 1 1 1 Coilin N-terminus CPSF100_C PF13299.6 RKP03085.1 - 0.019 15.2 4.1 0.017 15.3 4.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 RKP03085.1 - 0.02 14.9 31.1 0.021 14.9 31.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 RKP03085.1 - 0.068 13.1 12.0 0.076 13.0 12.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 RKP03085.1 - 0.11 12.6 8.5 0.11 12.6 8.5 1.1 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 RKP03085.1 - 0.17 11.9 5.7 0.15 12.1 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TERB2 PF15101.6 RKP03085.1 - 0.51 10.3 18.0 0.57 10.2 18.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SID-1_RNA_chan PF13965.6 RKP03085.1 - 0.57 8.5 1.5 0.49 8.7 1.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4407 PF14362.6 RKP03085.1 - 1.9 7.7 20.0 2.4 7.4 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpoIIP PF07454.11 RKP03085.1 - 2.7 7.4 14.9 2.9 7.3 14.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 RKP03085.1 - 3 6.5 18.6 3.2 6.4 18.6 1.0 1 0 0 1 1 1 0 Presenilin DUF775 PF05603.12 RKP03085.1 - 6.1 6.3 14.4 7.5 6.0 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Connexin PF00029.19 RKP03085.1 - 6.3 6.5 11.6 7.3 6.3 11.6 1.1 1 0 0 1 1 1 0 Connexin EOS1 PF12326.8 RKP03085.1 - 6.8 6.6 9.5 7.7 6.4 9.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein PAT1 PF09770.9 RKP03085.1 - 7.9 4.6 24.7 8.4 4.5 24.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 RKP03085.1 - 8 6.4 12.2 9 6.2 12.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Activator_LAG-3 PF11498.8 RKP03085.1 - 8.3 5.3 39.9 9 5.1 39.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RR_TM4-6 PF06459.12 RKP03085.1 - 8.6 6.1 16.6 9.6 5.9 16.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 RKP03086.1 - 8.5e-43 146.6 0.0 9.5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03086.1 - 2e-27 96.1 0.0 2.1e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP03086.1 - 1.1e-06 28.1 0.0 2.6e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RKP03086.1 - 0.0047 16.9 0.1 0.05 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RKP03086.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Svf1_C PF17187.4 RKP03087.1 - 4.3e-34 117.7 0.0 6.3e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Myco_19_kDa PF05481.12 RKP03087.1 - 0.19 12.0 0.9 3.4 8.0 0.0 3.0 2 1 2 4 4 4 0 Mycobacterium 19 kDa lipoprotein antigen Sec23_trunk PF04811.15 RKP03088.1 - 2.4e-70 236.9 0.8 3.9e-70 236.2 0.2 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 RKP03088.1 - 3e-26 91.2 0.1 1.4e-25 89.1 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RKP03088.1 - 5e-16 59.2 0.1 9.4e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 RKP03088.1 - 6.9e-16 58.0 4.9 6.9e-16 58.0 4.9 1.7 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 RKP03088.1 - 1.5e-07 31.2 0.0 3.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 RKP03088.1 - 0.012 15.0 0.4 0.031 13.7 0.4 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 RKP03088.1 - 0.093 13.4 0.6 6.3 7.5 0.3 3.0 3 0 0 3 3 3 0 von Willebrand factor type A domain LRR_8 PF13855.6 RKP03089.1 - 0.0029 17.3 3.1 1.3 8.9 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat DivIC PF04977.15 RKP03089.1 - 8.9 6.2 13.7 0.21 11.4 4.8 2.8 3 0 0 3 3 3 0 Septum formation initiator SH3_1 PF00018.28 RKP03090.1 - 4.6e-06 26.1 0.0 8.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP03090.1 - 0.00036 20.3 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP03090.1 - 0.00042 19.9 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Inositol_P PF00459.25 RKP03091.1 - 1.3e-49 169.2 0.9 1.7e-49 168.8 0.9 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Methyltr_RsmB-F PF01189.17 RKP03092.1 - 3.7e-21 75.7 0.0 5.3e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RKP03092.1 - 0.00027 21.1 0.0 0.0097 16.0 0.0 2.7 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 RKP03092.1 - 0.0096 16.6 0.0 0.93 10.2 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKP03092.1 - 0.0096 15.7 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 RKP03092.1 - 0.027 14.3 0.0 0.76 9.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 RKP03094.1 - 6.8e-76 255.1 0.0 8e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03094.1 - 4.8e-31 108.0 0.0 6.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP03094.1 - 0.00041 19.8 0.0 0.0013 18.1 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKP03094.1 - 0.0029 16.6 0.1 0.66 8.9 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 RKP03094.1 - 0.0033 16.8 0.1 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP03094.1 - 0.018 14.9 3.3 0.069 13.1 0.1 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 RKP03094.1 - 0.028 13.5 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 RKP03094.1 - 0.086 12.5 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 RKP03095.1 - 1.3e-11 44.1 0.0 4.5e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAP7 PF05672.11 RKP03095.1 - 0.017 14.8 19.2 0.032 13.9 19.2 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family WD40 PF00400.32 RKP03096.1 - 2.6e-34 116.7 19.9 0.0021 18.9 0.3 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat Nucleoporin_N PF08801.11 RKP03096.1 - 6.8e-07 28.4 0.1 0.00051 18.9 0.0 3.0 2 1 0 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.6 RKP03096.1 - 0.00073 19.6 0.0 0.06 13.4 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region AsnC_trans_reg PF01037.21 RKP03096.1 - 0.0018 18.2 0.0 1.7 8.6 0.0 2.8 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain FIST PF08495.10 RKP03097.1 - 0.0041 17.2 0.0 0.0073 16.3 0.0 1.5 1 1 0 1 1 1 1 FIST N domain Rpr2 PF04032.16 RKP03098.1 - 0.006 16.8 1.8 0.027 14.8 1.8 2.3 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CAP_N PF01213.19 RKP03098.1 - 0.46 9.9 3.6 0.71 9.3 3.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.6 RKP03098.1 - 3.5 6.5 4.7 5.8 5.8 4.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 KH_1 PF00013.29 RKP03100.1 - 1.8e-65 216.7 0.5 1e-10 41.2 0.0 12.2 11 1 0 11 11 11 8 KH domain KH_2 PF07650.17 RKP03100.1 - 1.7e-06 27.8 1.0 4.9 7.0 0.1 5.8 6 0 0 6 6 6 3 KH domain YjbH PF06082.11 RKP03100.1 - 0.04 12.7 1.5 0.07 11.9 1.5 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH KH_4 PF13083.6 RKP03100.1 - 0.77 9.7 3.3 33 4.4 0.2 3.9 4 0 0 4 4 4 0 KH domain SPT2 PF08243.11 RKP03101.1 - 1.1e-11 45.2 23.2 1.1e-11 45.2 23.2 3.9 3 2 1 4 4 4 1 SPT2 chromatin protein Pkinase PF00069.25 RKP03102.1 - 8e-12 45.1 0.0 2.9e-10 40.0 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03102.1 - 3.1e-05 23.4 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Zn_clus PF00172.18 RKP03103.1 - 6.8e-06 26.1 5.7 6.8e-06 26.1 5.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ESR1_C PF12743.7 RKP03103.1 - 1.4 8.8 20.9 0.18 11.6 0.3 4.8 3 0 0 3 3 3 0 Oestrogen-type nuclear receptor final C-terminal MAPEG PF01124.18 RKP03104.1 - 5.4e-07 29.6 4.6 6.6e-07 29.3 4.6 1.2 1 0 0 1 1 1 1 MAPEG family Scramblase PF03803.15 RKP03105.1 - 2e-50 171.1 0.0 2.3e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Scramblase LOR PF04525.12 RKP03105.1 - 0.0087 15.7 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 LURP-one-related Coatomer_E PF04733.14 RKP03106.1 - 7.1e-20 71.6 4.8 8.5e-19 68.0 4.0 2.2 1 1 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 RKP03106.1 - 4.1 7.7 6.7 7.2 6.9 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1996 PF09362.10 RKP03107.1 - 1.2e-56 192.3 0.3 1.8e-56 191.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gp_dh_C PF02800.20 RKP03108.1 - 1.3e-67 226.3 0.0 2.1e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 RKP03108.1 - 2.2e-38 130.6 0.1 6.2e-38 129.2 0.1 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 RKP03108.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mob1_phocein PF03637.17 RKP03109.1 - 1.2e-26 93.8 0.0 8.8e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 Mob1/phocein family zf-RING_12 PF17976.1 RKP03109.1 - 0.099 12.9 0.2 0.23 11.7 0.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Methyltransf_25 PF13649.6 RKP03110.1 - 5.7e-11 43.0 0.0 1.2e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RKP03110.1 - 2.4e-09 37.0 0.0 3.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RKP03110.1 - 5.5e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKP03110.1 - 1.8e-08 34.9 0.0 4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP03110.1 - 3.3e-08 33.6 0.0 5e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RKP03110.1 - 6.9e-06 25.2 0.2 9.6e-06 24.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 RKP03110.1 - 0.00071 19.0 0.1 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 RKP03110.1 - 0.00085 20.0 0.0 0.0022 18.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKP03110.1 - 0.0022 17.6 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 RKP03110.1 - 0.003 16.9 0.1 0.0056 16.1 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 RKP03110.1 - 0.0075 16.2 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 RKP03110.1 - 0.0099 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 RKP03110.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 RKP03110.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase RhoGAP PF00620.27 RKP03111.1 - 3.1e-35 121.3 0.0 3.9e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Erythro-docking PF09277.11 RKP03111.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking Peptidase_M28 PF04389.17 RKP03112.1 - 1.2e-30 106.7 0.1 1.6e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 dCMP_cyt_deam_1 PF00383.23 RKP03113.1 - 3.3e-05 23.7 0.0 0.0001 22.1 0.0 1.8 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RKP03113.1 - 6.7e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Transglut_core PF01841.19 RKP03113.1 - 0.0061 17.0 0.4 0.014 15.9 0.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily HLH PF00010.26 RKP03114.1 - 1.1e-17 63.7 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDHD PF02862.17 RKP03114.1 - 0.0028 17.9 4.3 0.0059 16.8 4.3 1.5 1 0 0 1 1 1 1 DDHD domain PPL5 PF18168.1 RKP03114.1 - 0.068 12.5 6.0 0.12 11.7 6.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Activator_LAG-3 PF11498.8 RKP03114.1 - 0.16 10.9 40.4 0.45 9.4 40.4 1.8 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.16 RKP03114.1 - 0.19 11.8 6.5 0.4 10.7 6.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bud13 PF09736.9 RKP03114.1 - 0.35 11.3 14.2 1 9.8 14.2 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF3464 PF11947.8 RKP03114.1 - 0.41 10.4 8.1 0.86 9.4 8.1 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Zip PF02535.22 RKP03114.1 - 0.5 9.5 12.5 0.49 9.6 6.5 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 RKP03114.1 - 0.56 8.5 9.4 0.79 8.0 9.4 1.1 1 0 0 1 1 1 0 Smg8_Smg9 eIF-3_zeta PF05091.12 RKP03114.1 - 0.7 8.8 16.7 1 8.3 16.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 RKP03114.1 - 0.79 9.1 13.3 1.3 8.5 13.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Suf PF05843.14 RKP03114.1 - 0.86 9.5 16.2 1.9 8.4 16.2 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EPL1 PF10513.9 RKP03114.1 - 0.98 9.8 13.5 2.4 8.5 13.5 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Rrn6 PF10214.9 RKP03114.1 - 1.1 7.7 13.4 2.3 6.6 13.4 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Endostatin PF06482.11 RKP03114.1 - 1.5 8.2 14.0 3 7.2 14.0 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GREB1 PF15782.5 RKP03114.1 - 1.8 5.6 14.7 2.4 5.1 14.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 RKP03114.1 - 1.9 7.8 4.1 3.2 7.1 4.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MMR1 PF08505.10 RKP03114.1 - 2.5 8.3 16.8 5.7 7.2 16.8 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 RKP03114.1 - 2.7 6.7 18.4 4.5 5.9 18.4 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 RKP03114.1 - 2.7 6.7 11.4 5.4 5.7 11.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 RKP03114.1 - 2.7 6.8 13.7 4.1 6.2 13.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCU PF04678.13 RKP03114.1 - 2.8 8.0 7.4 6 6.9 7.4 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter RR_TM4-6 PF06459.12 RKP03114.1 - 2.8 7.7 14.7 5.2 6.8 14.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 RKP03114.1 - 3.5 5.8 28.1 5.7 5.1 28.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 RKP03114.1 - 4.2 7.4 21.5 7.3 6.6 21.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF913 PF06025.12 RKP03114.1 - 4.5 6.2 8.7 9.2 5.1 8.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2722 PF10846.8 RKP03114.1 - 4.6 6.1 34.0 9 5.1 34.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2464 PF10240.9 RKP03114.1 - 4.6 6.7 7.7 8.5 5.9 7.7 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 CCSAP PF15748.5 RKP03114.1 - 5.4 7.1 21.3 16 5.6 21.3 1.7 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Spt20 PF12090.8 RKP03114.1 - 6.2 6.4 46.6 10 5.6 46.6 1.2 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 RKP03114.1 - 7.4 6.7 14.0 19 5.4 14.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 RKP03114.1 - 7.8 5.5 12.4 19 4.2 12.4 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Connexin PF00029.19 RKP03114.1 - 7.9 6.2 13.1 14 5.4 13.1 1.3 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 RKP03114.1 - 8.3 6.1 8.8 17 5.1 8.8 1.4 1 0 0 1 1 1 0 FAM176 family DUF4820 PF16091.5 RKP03114.1 - 8.4 5.7 12.0 17 4.7 12.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) EOS1 PF12326.8 RKP03114.1 - 8.6 6.3 6.9 16 5.4 6.9 1.3 1 0 0 1 1 1 0 N-glycosylation protein zf-MYND PF01753.18 RKP03115.1 - 0.0014 18.7 6.4 0.0026 17.8 6.4 1.5 1 0 0 1 1 1 1 MYND finger YpzG PF14139.6 RKP03115.1 - 0.095 12.9 0.2 0.25 11.6 0.2 1.7 1 0 0 1 1 1 0 YpzG-like protein DUF1996 PF09362.10 RKP03116.1 - 1.7e-56 191.9 0.4 2.1e-56 191.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MerR-DNA-bind PF09278.11 RKP03117.1 - 0.0062 17.0 0.3 0.011 16.3 0.3 1.3 1 0 0 1 1 1 1 MerR, DNA binding MIF4G PF02854.19 RKP03118.1 - 3.6e-36 124.8 0.4 6.3e-36 124.0 0.4 1.4 1 1 0 1 1 1 1 MIF4G domain BAF PF02961.14 RKP03118.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Barrier to autointegration factor Uteroglobin PF01099.17 RKP03118.1 - 0.18 12.2 1.0 3.6 8.0 0.4 2.5 2 0 0 2 2 2 0 Uteroglobin family HMG-CoA_red PF00368.18 RKP03120.1 - 5.7e-94 315.1 1.6 9e-94 314.5 1.6 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase BCDHK_Adom3 PF10436.9 RKP03121.1 - 1.4e-36 125.8 0.0 2.9e-36 124.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RKP03121.1 - 0.00014 22.3 0.0 0.00067 20.1 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_1 PF00013.29 RKP03122.1 - 0.00021 21.0 0.7 0.0004 20.1 0.7 1.4 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 RKP03122.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Krr1 KH1 domain RRM_1 PF00076.22 RKP03123.1 - 0.046 13.5 0.0 0.59 10.0 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 RKP03124.1 - 0.0025 17.8 13.1 1.9 8.8 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03124.1 - 0.016 15.5 10.7 4.9 7.5 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03124.1 - 0.04 14.3 0.1 24 5.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03124.1 - 0.17 11.8 1.1 3.7 7.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DAO PF01266.24 RKP03125.1 - 1.8e-18 67.3 0.4 2.4e-18 66.8 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 RKP03125.1 - 4.5e-12 45.7 0.0 1.2e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAT PF02259.23 RKP03126.1 - 1e-62 212.4 3.1 1e-62 212.4 3.1 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 RKP03126.1 - 5.3e-29 101.8 0.2 9.7e-29 100.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FMN_red PF03358.15 RKP03127.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 RKP03127.1 - 0.031 14.5 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 Flavodoxin Mpv17_PMP22 PF04117.12 RKP03128.1 - 1e-17 64.1 2.8 2.2e-17 63.0 2.8 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-HC5HC2H_2 PF13832.6 RKP03129.1 - 1.2e-32 112.3 8.0 1.2e-32 112.3 8.0 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 RKP03129.1 - 5.9e-21 74.5 6.1 5.9e-21 74.5 6.1 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 RKP03129.1 - 1.4e-15 56.5 2.5 1.4e-15 56.5 2.5 3.0 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 RKP03129.1 - 5.2e-12 46.4 0.0 6.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD PF00628.29 RKP03129.1 - 5.8e-10 38.9 8.8 5.8e-10 38.9 8.8 3.1 4 0 0 4 4 4 2 PHD-finger zf-PHD-like PF15446.6 RKP03129.1 - 0.0022 17.6 2.5 0.0022 17.6 2.5 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 RKP03129.1 - 0.0075 16.1 1.2 0.0075 16.1 1.2 3.2 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CEBP_ZZ PF16366.5 RKP03129.1 - 8.4 6.7 27.2 4.2 7.7 9.9 3.4 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain UAA PF08449.11 RKP03130.1 - 1.5e-75 254.2 1.9 2.1e-75 253.7 1.9 1.1 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 RKP03130.1 - 0.24 10.3 4.2 0.1 11.5 0.5 1.9 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like RskA PF10099.9 RKP03130.1 - 0.45 10.8 6.4 4.8 7.4 3.8 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Tetraspanin PF00335.20 RKP03130.1 - 5.7 6.6 7.0 0.27 10.9 0.2 2.2 2 1 0 2 2 2 0 Tetraspanin family Actin PF00022.19 RKP03131.1 - 2.6e-23 82.3 0.1 1e-22 80.4 0.1 1.7 1 1 0 1 1 1 1 Actin Ribosomal_S5_C PF03719.15 RKP03132.1 - 2.2e-21 75.1 0.1 3.1e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 RKP03132.1 - 5.8e-16 58.2 0.2 1e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF2045 PF09741.9 RKP03133.1 - 3e-35 121.7 0.0 1.6e-34 119.3 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) RRM_1 PF00076.22 RKP03134.1 - 4e-45 151.5 0.0 5.3e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03134.1 - 0.00017 21.6 0.0 0.04 14.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 RKP03134.1 - 0.00024 20.7 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 RKP03134.1 - 0.0018 18.2 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_occluded PF16842.5 RKP03134.1 - 0.021 14.7 0.0 2.8 7.9 0.0 2.5 2 1 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 RKP03134.1 - 0.11 12.6 0.0 20 5.3 0.0 2.4 2 1 0 2 2 2 0 RNA binding motif Kinesin PF00225.23 RKP03135.1 - 3.2e-95 318.9 0.0 3.6e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP03135.1 - 3.7e-19 69.2 0.0 2.6e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 RKP03135.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein ALAD PF00490.21 RKP03136.1 - 7.4e-118 393.3 0.0 8.9e-118 393.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Biopterin_H PF00351.21 RKP03137.1 - 1.5e-160 533.7 0.0 1.8e-160 533.4 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 RKP03137.1 - 4.9e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 RKP03137.1 - 0.0045 17.5 0.0 0.0091 16.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain BAG PF02179.16 RKP03138.1 - 1.4e-12 47.9 0.0 4.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 BAG domain Hydant_A_N PF05378.13 RKP03138.1 - 0.01 15.5 0.2 0.015 15.0 0.2 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region ubiquitin PF00240.23 RKP03138.1 - 0.1 12.3 0.0 14 5.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Hydrolase_3 PF08282.12 RKP03139.1 - 4.2e-34 118.4 0.0 1.2e-26 94.0 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 RKP03139.1 - 3.1e-11 43.3 0.0 4.8e-08 32.8 0.0 2.9 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 RKP03139.1 - 3.6e-05 24.1 0.8 0.001 19.4 0.8 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 RKP03139.1 - 0.00011 22.7 0.0 0.03 14.7 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase zf-C2H2 PF00096.26 RKP03141.1 - 3.3e-13 49.3 3.7 2e-06 27.9 0.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP03141.1 - 9.9e-11 41.5 2.5 2.4e-05 24.8 0.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 RKP03141.1 - 1.4e-08 34.8 0.7 0.0012 19.2 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 RKP03141.1 - 6.1e-08 32.8 3.8 2.2e-06 27.9 0.2 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RKP03141.1 - 1.1e-05 25.6 0.1 0.041 14.2 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP03141.1 - 0.00055 19.9 2.9 0.026 14.5 0.3 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-MYST PF17772.1 RKP03141.1 - 0.0064 16.1 0.3 0.14 11.8 0.1 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain zf-Di19 PF05605.12 RKP03141.1 - 0.0091 16.3 0.1 1 9.7 0.0 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 RKP03141.1 - 0.018 15.4 0.4 2.8 8.3 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 RKP03141.1 - 0.024 14.5 0.9 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 RKP03141.1 - 0.036 14.8 0.2 2.6 8.7 0.0 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 RKP03141.1 - 0.074 12.8 2.5 0.35 10.7 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 RKP03141.1 - 0.082 12.5 0.9 3 7.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 RKP03141.1 - 0.091 12.7 0.1 0.091 12.7 0.1 2.4 3 1 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RKP03141.1 - 0.11 12.6 1.9 0.54 10.4 1.8 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 RKP03141.1 - 0.61 10.0 5.5 8.2 6.4 4.7 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Myosin_head PF00063.21 RKP03142.1 - 7.1e-222 738.4 1.8 4.5e-218 725.8 1.8 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 RKP03142.1 - 8.7e-37 125.9 0.4 3.7e-18 66.0 0.0 3.2 3 0 0 3 3 3 2 MyTH4 domain FERM_M PF00373.18 RKP03142.1 - 9.1e-30 103.5 0.5 1.3e-14 54.6 0.0 3.5 3 0 0 3 3 3 2 FERM central domain RA PF00788.23 RKP03142.1 - 9.6e-10 39.0 0.0 0.0001 22.9 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 RKP03142.1 - 0.0097 15.8 0.0 5.9 6.9 0.0 2.5 2 0 0 2 2 2 2 FERM N-terminal domain AAA_16 PF13191.6 RKP03142.1 - 0.072 13.5 0.1 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain IQ PF00612.27 RKP03142.1 - 2.3 8.2 10.2 7.2 6.7 5.2 3.0 2 0 0 2 2 2 0 IQ calmodulin-binding motif SNAP PF14938.6 RKP03143.1 - 3.4e-101 338.4 14.0 3.8e-101 338.2 14.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 RKP03143.1 - 3.2e-05 24.1 13.7 0.0027 17.9 0.7 4.0 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03143.1 - 0.002 18.2 6.5 29 5.2 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 RKP03143.1 - 0.0022 17.2 3.1 0.0034 16.5 0.5 2.1 1 1 0 2 2 2 1 Spatacsin C-terminus TPR_MalT PF17874.1 RKP03143.1 - 0.0034 16.8 5.1 0.0081 15.6 4.7 1.7 1 1 1 2 2 2 1 MalT-like TPR region RPN7 PF10602.9 RKP03143.1 - 0.0035 17.1 1.8 0.0057 16.4 0.8 1.9 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 RKP03143.1 - 0.004 17.1 11.6 4.5 7.5 0.0 6.6 5 2 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKP03143.1 - 0.016 15.9 19.0 1.2 10.1 0.1 6.2 3 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03143.1 - 0.021 14.5 8.5 46 3.8 0.7 6.2 6 2 1 7 7 7 0 TPR repeat DHR-2 PF06920.13 RKP03143.1 - 0.098 11.3 0.1 0.18 10.4 0.1 1.4 1 1 0 1 1 1 0 Dock homology region 2 DUF4375 PF14300.6 RKP03143.1 - 0.1 12.9 0.8 8.8 6.6 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4375) TPR_1 PF00515.28 RKP03143.1 - 0.15 12.0 11.7 34 4.5 0.0 6.3 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03143.1 - 0.42 11.4 20.6 3 8.7 0.1 6.8 4 2 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP03143.1 - 1.4 9.2 4.9 23 5.3 0.1 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 RKP03143.1 - 1.4 9.2 23.8 11 6.4 0.0 7.5 5 2 3 9 9 8 0 Tetratricopeptide repeat DUF202 PF02656.15 RKP03144.1 - 1.5e-15 57.4 4.9 1.5e-15 57.4 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3278 PF11683.8 RKP03144.1 - 0.08 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) SNF2_N PF00176.23 RKP03145.1 - 5.3e-66 222.7 0.0 7.4e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKP03145.1 - 1.6e-19 70.3 0.0 3.5e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP03145.1 - 6.1e-06 26.3 0.0 6.5e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 RKP03145.1 - 0.00015 21.1 0.0 0.00053 19.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.6 RKP03145.1 - 0.012 15.4 0.0 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.6 RKP03146.1 - 5.9e-05 23.2 0.0 0.0077 16.4 0.0 2.6 2 0 0 2 2 2 2 PPR repeat family ECH_1 PF00378.20 RKP03147.1 - 9.4e-58 195.5 0.2 1.1e-57 195.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKP03147.1 - 1.6e-31 110.1 1.3 5.5e-29 101.7 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SIR2 PF02146.17 RKP03149.1 - 1.6e-48 165.0 0.0 6.8e-48 162.9 0.0 1.8 1 1 0 1 1 1 1 Sir2 family zf-RING_7 PF02591.15 RKP03149.1 - 0.017 15.3 0.1 0.05 13.8 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain DUF3421 PF11901.8 RKP03150.1 - 6.4e-19 68.0 0.2 7.6e-19 67.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) CsbD PF05532.12 RKP03153.1 - 5.1e-07 29.5 0.1 6.8e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 CsbD-like PaaB PF06243.11 RKP03153.1 - 0.13 12.5 0.3 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 Phenylacetic acid degradation B dCache_1 PF02743.18 RKP03155.1 - 1.4e-10 41.4 8.2 2.3e-10 40.7 4.6 2.6 1 1 1 2 2 2 1 Cache domain Golgin_A5 PF09787.9 RKP03156.1 - 0.0041 16.6 19.0 0.0055 16.2 19.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 RKP03156.1 - 0.0059 16.2 16.9 0.0082 15.7 16.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc7 PF08317.11 RKP03156.1 - 0.0087 15.0 26.2 0.0067 15.4 24.2 1.7 1 1 1 2 2 2 2 Spc7 kinetochore protein MAD PF05557.13 RKP03156.1 - 0.0093 14.4 21.6 0.011 14.1 21.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Atg14 PF10186.9 RKP03156.1 - 0.079 12.0 26.9 0.13 11.3 26.9 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec20 PF03908.13 RKP03156.1 - 0.11 12.4 12.9 0.52 10.3 6.2 2.3 1 1 1 2 2 2 0 Sec20 AIP3 PF03915.13 RKP03156.1 - 0.19 10.8 21.9 0.28 10.2 21.9 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 RKP03156.1 - 0.19 11.8 36.5 0.081 13.0 13.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 RKP03156.1 - 0.2 12.0 28.4 0.23 11.8 23.1 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fez1 PF06818.15 RKP03156.1 - 0.34 11.3 24.8 0.27 11.6 22.6 1.8 1 1 1 2 2 2 0 Fez1 DUF4201 PF13870.6 RKP03156.1 - 0.39 10.4 19.6 0.44 10.3 17.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 RKP03156.1 - 1.1 9.8 14.3 0.83 10.2 10.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATG16 PF08614.11 RKP03156.1 - 1.4 9.1 37.2 0.32 11.2 33.7 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec8_exocyst PF04048.14 RKP03156.1 - 1.7 8.5 25.2 2.2e+02 1.7 4.7 3.5 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain JIP_LZII PF16471.5 RKP03156.1 - 2.1 8.6 11.9 23 5.2 2.1 2.8 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II UPF0449 PF15136.6 RKP03156.1 - 2.1 8.9 20.7 52 4.4 2.6 3.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF4695 PF15766.5 RKP03156.1 - 2.1 8.6 19.5 23 5.3 0.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) HIP1_clath_bdg PF16515.5 RKP03156.1 - 2.3 8.9 28.5 1.6e+03 -0.3 28.5 2.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 RKP03156.1 - 2.3 8.3 27.8 5.3 7.1 6.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 RKP03156.1 - 2.4 8.2 17.4 3.4 7.7 17.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 RKP03156.1 - 3.2 5.6 14.5 4 5.2 14.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 RKP03156.1 - 3.9 6.8 26.6 9.1 5.6 19.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TBCA PF02970.16 RKP03156.1 - 4.6 7.7 20.4 1.3 9.4 10.5 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A Prominin PF05478.11 RKP03156.1 - 6.3 4.6 10.3 8.2 4.2 10.3 1.3 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.8 RKP03156.1 - 6.5 6.0 29.2 3.9 6.7 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Peptidase_S10 PF00450.22 RKP03158.1 - 3.3e-103 346.3 0.0 3.7e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase 4HBT PF03061.22 RKP03160.1 - 1.4e-06 28.6 0.0 0.037 14.4 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily GMP_synt_C PF00958.22 RKP03161.1 - 6.5e-46 154.3 0.0 1.4e-45 153.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 RKP03161.1 - 5.5e-37 127.4 0.0 1.1e-36 126.4 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 RKP03161.1 - 1.6e-08 33.9 0.0 3.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 RKP03161.1 - 4.6e-08 33.1 0.1 1.6e-07 31.3 0.0 1.9 2 1 0 2 2 2 1 Peptidase C26 tRNA_Me_trans PF03054.16 RKP03161.1 - 0.0013 17.6 0.1 0.0025 16.7 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 RKP03161.1 - 0.0049 16.4 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 RKP03161.1 - 0.0083 15.5 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 RKP03161.1 - 0.025 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 RKP03161.1 - 0.027 14.1 0.2 0.056 13.0 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 RKP03165.1 - 9.5e-14 51.7 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 THUMP domain Lir1 PF07207.11 RKP03165.1 - 0.07 13.4 0.8 0.15 12.3 0.6 1.8 1 1 0 1 1 1 0 Light regulated protein Lir1 JIP_LZII PF16471.5 RKP03166.1 - 3.7 7.8 8.2 5.1 7.3 0.7 3.4 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Pkinase PF00069.25 RKP03167.1 - 4.2e-66 223.0 0.0 4.8e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03167.1 - 1.5e-40 139.1 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RKP03167.1 - 0.00098 18.8 0.2 0.0016 18.1 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RKP03167.1 - 0.0013 18.2 1.6 0.0018 17.7 1.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKP03167.1 - 0.0025 16.7 0.2 0.0037 16.1 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RKP03167.1 - 0.011 14.8 0.5 0.022 13.7 0.5 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RKP03167.1 - 0.025 14.5 1.2 1.5 8.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP03167.1 - 0.038 13.3 2.5 0.34 10.2 0.2 2.7 2 1 0 2 2 2 0 Kinase-like DUF2855 PF11017.8 RKP03168.1 - 0.12 12.1 1.2 0.19 11.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) CDC73_C PF05179.14 RKP03169.1 - 4.1e-49 166.3 0.2 5.5e-49 165.9 0.2 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 RKP03169.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal Nop PF01798.18 RKP03170.1 - 3e-77 259.2 0.0 3e-77 259.2 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RKP03170.1 - 6.6e-14 52.0 0.0 6.6e-14 52.0 0.0 2.4 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DAG_kinase_N PF14513.6 RKP03170.1 - 0.098 12.9 7.8 2 8.6 5.5 2.9 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus RR_TM4-6 PF06459.12 RKP03170.1 - 1 9.2 17.4 1.7 8.4 17.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 RKP03170.1 - 2.4 6.4 17.8 3.2 5.9 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 RKP03170.1 - 6.7 6.8 8.8 12 6.0 8.8 1.4 1 0 0 1 1 1 0 DDHD domain MMR_HSR1 PF01926.23 RKP03171.1 - 5.7e-16 58.6 0.1 1.2e-14 54.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKP03171.1 - 1.1e-09 38.4 0.0 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 RKP03171.1 - 4e-07 29.7 0.1 3.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF2681 PF10883.8 RKP03171.1 - 0.0021 18.4 0.5 0.0038 17.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Dynamin_N PF00350.23 RKP03171.1 - 0.038 14.0 1.5 0.17 12.0 0.0 2.4 3 0 0 3 3 3 0 Dynamin family AIG1 PF04548.16 RKP03171.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family CDC45 PF02724.14 RKP03171.1 - 2.4 6.3 6.6 3.6 5.8 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein UCH PF00443.29 RKP03172.1 - 2.1e-36 125.8 0.0 3.6e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP03172.1 - 3e-05 23.8 0.0 0.00079 19.1 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S2 PF00318.20 RKP03173.1 - 6.5e-24 84.4 0.8 3.3e-13 49.4 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 RKP03173.1 - 1.4e-06 29.5 19.4 3.3e-06 28.4 19.4 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus CHCH PF06747.13 RKP03174.1 - 4.2e-05 23.5 1.4 0.042 14.0 0.1 2.1 2 0 0 2 2 2 2 CHCH domain COX6B PF02297.17 RKP03174.1 - 0.00044 20.4 0.1 0.00052 20.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.13 RKP03174.1 - 0.00065 20.0 0.1 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 RKP03174.1 - 0.0012 18.8 0.1 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CxC7 PF18866.1 RKP03174.1 - 0.0098 16.0 0.1 0.072 13.2 0.0 1.9 2 0 0 2 2 2 1 CxC7 like cysteine cluster associated with KDZ transposases DUF3128 PF11326.8 RKP03174.1 - 0.038 14.4 1.0 3.4 8.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) CX9C PF16860.5 RKP03174.1 - 0.06 13.4 0.4 0.39 10.8 0.1 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-CHCC PF10276.9 RKP03175.1 - 1.4e-17 63.4 1.5 2.1e-17 62.9 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain DUF5324 PF17258.2 RKP03175.1 - 0.02 14.6 0.8 0.022 14.4 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5324) EnY2 PF10163.9 RKP03176.1 - 1.5e-21 76.5 0.5 1.8e-21 76.2 0.5 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 CobW_C PF07683.14 RKP03176.1 - 0.019 14.9 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain DUF892 PF05974.12 RKP03176.1 - 0.075 13.1 0.6 0.091 12.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) MitMem_reg PF13012.6 RKP03177.1 - 2.6e-37 127.7 1.1 4.4e-37 126.9 1.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 RKP03177.1 - 2.5e-32 111.3 0.0 4.9e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Eaf7 PF07904.13 RKP03178.1 - 5.3e-10 39.6 0.0 5.3e-10 39.6 0.0 2.8 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Inv-AAD PF18785.1 RKP03179.1 - 1e-31 109.5 0.0 1.4e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 RKP03179.1 - 1.1e-17 63.7 0.3 1.4e-17 63.4 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RKP03179.1 - 2.3e-07 30.6 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 RKP03179.1 - 0.0008 19.3 0.0 0.0009 19.2 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 RKP03179.1 - 0.033 14.3 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 WD40 PF00400.32 RKP03180.1 - 1.5e-17 63.6 9.5 0.018 15.9 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03180.1 - 1.1e-14 54.5 0.1 0.033 14.5 0.2 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RKP03180.1 - 0.006 15.0 0.0 0.058 11.7 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 RKP03180.1 - 0.01 14.4 0.1 0.07 11.7 0.0 2.0 1 1 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 RKP03180.1 - 0.023 13.7 2.4 0.038 12.9 0.4 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 RKP03180.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 WD40-like domain VID27 PF08553.10 RKP03180.1 - 0.21 10.6 0.2 1.4 7.9 0.1 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 RKP03180.1 - 5.1 7.7 8.8 11 6.6 0.0 4.7 4 1 0 4 4 4 0 PQQ-like domain Sec39 PF08314.11 RKP03181.1 - 6.5e-11 41.4 0.0 0.00012 20.7 0.0 2.4 2 0 0 2 2 2 2 Secretory pathway protein Sec39 UBA PF00627.31 RKP03181.1 - 0.11 12.4 0.4 6.6 6.8 0.1 3.1 2 0 0 2 2 2 0 UBA/TS-N domain ANAPC4_WD40 PF12894.7 RKP03181.1 - 0.14 12.5 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 RKP03181.1 - 0.14 11.4 0.0 0.4 10.0 0.0 1.7 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Nbas_N PF15492.6 RKP03182.1 - 0.051 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Clr2 PF10383.9 RKP03182.1 - 0.14 13.0 1.1 1.9 9.3 0.1 2.6 1 1 0 2 2 2 0 Transcription-silencing protein Clr2 FAM183 PF14886.6 RKP03184.1 - 0.019 15.7 0.0 0.14 12.9 0.1 2.2 2 0 0 2 2 2 0 FAM183A and FAM183B related GFO_IDH_MocA PF01408.22 RKP03185.1 - 3.1e-11 44.1 0.7 2.1e-10 41.4 0.2 2.6 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold WD40 PF00400.32 RKP03186.1 - 2.7e-16 59.7 7.8 6.9e-05 23.6 0.4 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03186.1 - 2e-06 28.0 0.0 0.077 13.3 0.0 4.4 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain COX15-CtaA PF02628.15 RKP03187.1 - 1.2e-101 340.1 10.8 1.4e-101 339.9 10.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RRM_1 PF00076.22 RKP03188.1 - 1.8e-13 50.1 0.1 2.6e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RKP03188.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 RKP03188.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03188.1 - 0.12 12.5 0.3 0.3 11.2 0.1 1.7 2 1 0 2 2 2 0 RNA recognition motif Spo7_2_N PF15407.6 RKP03188.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Sporulation protein family 7 HSF_DNA-bind PF00447.17 RKP03189.1 - 6.9e-26 90.7 0.1 1.1e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3450 PF11932.8 RKP03189.1 - 1.6 8.0 6.8 0.14 11.4 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cyt-b5 PF00173.28 RKP03190.1 - 5e-21 74.6 0.0 5.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vps54 PF07928.12 RKP03191.1 - 9.3e-38 129.7 3.1 9.8e-38 129.6 0.1 2.6 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 RKP03191.1 - 2.8e-08 33.4 0.6 2.3e-07 30.4 0.1 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex SUIM_assoc PF16619.5 RKP03191.1 - 0.0069 16.4 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Zw10 PF06248.13 RKP03191.1 - 0.016 13.8 0.1 0.027 13.1 0.1 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Nro1 PF12753.7 RKP03192.1 - 0.067 12.1 0.5 0.1 11.5 0.5 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 NAD_binding_1 PF00175.21 RKP03193.1 - 2.2e-25 89.4 0.0 3.1e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RKP03193.1 - 1.8e-20 73.1 0.0 3.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RKP03193.1 - 2.9e-05 24.2 0.2 0.0024 18.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF1659 PF07872.11 RKP03193.1 - 0.039 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Actin PF00022.19 RKP03194.1 - 5.6e-85 285.4 0.0 1.8e-83 280.4 0.0 2.0 1 1 0 1 1 1 1 Actin PPR PF01535.20 RKP03195.1 - 3.3e-05 23.8 0.0 1.9 8.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_2 PF13041.6 RKP03195.1 - 0.00061 19.9 0.0 0.011 15.9 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family FSIP1 PF15554.6 RKP03196.1 - 0.00079 18.6 0.3 0.14 11.2 0.0 3.0 3 0 0 3 3 3 3 FSIP1 family adh_short PF00106.25 RKP03197.1 - 8.3e-11 41.7 1.0 2.6e-10 40.1 1.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKP03197.1 - 1.4e-08 34.6 1.0 3.1e-08 33.5 1.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 RKP03197.1 - 9.1e-05 22.0 0.1 0.00031 20.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Spo7 PF03907.13 RKP03198.1 - 0.00033 20.2 0.4 0.17 11.3 0.1 2.2 2 0 0 2 2 2 2 Spo7-like protein ZapC PF07126.12 RKP03198.1 - 0.0026 17.4 0.3 0.004 16.8 0.3 1.2 1 0 0 1 1 1 1 Cell-division protein ZapC Tmemb_18A PF09771.9 RKP03198.1 - 0.13 12.7 0.2 3.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 DSPc PF00782.20 RKP03199.1 - 0.00086 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKP03199.1 - 0.0064 16.1 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-U1 PF06220.12 RKP03201.1 - 3.2e-07 30.0 0.6 5.2e-07 29.3 0.6 1.4 1 0 0 1 1 1 1 U1 zinc finger CTU2 PF10288.9 RKP03201.1 - 0.19 11.9 1.4 0.34 11.2 1.4 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Nucleoporin_FG PF13634.6 RKP03202.1 - 2.4e-33 114.8 114.5 6.8e-11 42.9 25.0 6.6 2 2 4 6 6 6 5 Nucleoporin FG repeat region DUF4763 PF15960.5 RKP03202.1 - 0.13 11.6 5.1 0.045 13.1 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 RKP03202.1 - 0.24 11.5 1.3 0.63 10.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HALZ PF02183.18 RKP03202.1 - 0.26 11.6 0.1 0.26 11.6 0.1 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper LTXXQ PF07813.12 RKP03202.1 - 0.26 12.0 2.0 0.52 11.1 2.0 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein RNA_pol_A_CTD PF03118.15 RKP03202.1 - 0.27 11.0 0.5 5.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain CCDC-167 PF15188.6 RKP03202.1 - 0.57 10.6 1.6 40 4.6 1.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 LMBR1 PF04791.16 RKP03203.1 - 2.6e-09 36.5 15.7 2.9e-09 36.4 8.3 2.4 3 0 0 3 3 3 2 LMBR1-like membrane protein DUF716 PF04819.12 RKP03203.1 - 0.074 12.7 3.8 0.17 11.5 3.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF716) JAB PF01398.21 RKP03204.1 - 3e-09 36.9 0.0 9.5e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RKP03204.1 - 3.9e-09 36.9 0.0 7.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UCH_1 PF13423.6 RKP03205.1 - 1.4e-58 199.0 0.0 3.7e-58 197.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 RKP03205.1 - 5.8e-20 72.5 0.0 9.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 RKP03205.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hen1_Lam_C PF18441.1 RKP03205.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain DnaJ PF00226.31 RKP03206.1 - 7e-22 77.3 0.5 1.3e-21 76.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 RKP03206.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKP03206.1 - 0.03 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type SRR PF07709.11 RKP03206.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Seven Residue Repeat zf-C2H2 PF00096.26 RKP03206.1 - 0.22 12.0 0.2 0.5 10.9 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Mannosyl_trans3 PF11051.8 RKP03207.1 - 2.5e-47 161.5 0.0 1.2e-46 159.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Sulfate_transp PF00916.20 RKP03208.1 - 7.5e-79 265.2 16.8 1e-78 264.8 16.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 RKP03208.1 - 4.4e-15 55.3 0.0 7.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 RKP03208.1 - 0.017 15.5 0.0 0.085 13.2 0.0 2.2 2 0 0 2 2 2 0 STAS domain RRM_1 PF00076.22 RKP03209.1 - 1e-13 50.8 0.0 1.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 RKP03209.1 - 4.6e-09 36.7 2.8 7.3e-09 36.1 2.8 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Exonuc_VII_L PF02601.15 RKP03210.1 - 0.16 11.5 12.3 0.49 9.9 3.8 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit CwfJ_C_1 PF04677.15 RKP03212.1 - 2.4e-10 40.3 0.0 6.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 RKP03212.1 - 4.8e-08 33.8 0.0 3.2e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 RKP03212.1 - 0.11 13.3 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 HIT domain Macoilin PF09726.9 RKP03212.1 - 0.18 10.3 12.0 0.27 9.7 12.0 1.2 1 0 0 1 1 1 0 Macoilin family Metallophos PF00149.28 RKP03213.1 - 1.8e-33 116.7 0.1 2.4e-33 116.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DPM2 PF07297.12 RKP03214.1 - 0.011 16.0 0.6 0.6 10.5 0.1 2.2 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) LapA_dom PF06305.11 RKP03214.1 - 3 7.7 5.2 3 7.7 0.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EAP30 PF04157.16 RKP03215.1 - 5.9e-67 225.4 0.0 6.6e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family EutK_C PF16365.5 RKP03215.1 - 0.0032 17.5 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilization protein EutK C-terminus CCDC24 PF15669.5 RKP03216.1 - 0.04 13.8 1.4 1.4 8.8 0.7 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family XRN_M PF17846.1 RKP03216.1 - 0.049 12.6 0.6 1.1 8.2 0.7 2.2 2 0 0 2 2 2 0 Xrn1 helical domain FKS1_dom1 PF14288.6 RKP03216.1 - 0.052 13.9 0.3 4.5 7.6 0.1 2.6 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 GATase_2 PF00310.21 RKP03217.1 - 1.9e-171 570.5 0.0 2.5e-171 570.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 RKP03217.1 - 3.2e-152 506.9 0.0 5.8e-151 502.8 0.0 2.6 3 0 0 3 3 3 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 RKP03217.1 - 2.8e-108 361.6 0.0 9.2e-108 359.9 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 RKP03217.1 - 1.2e-83 279.4 0.0 2.1e-83 278.6 0.0 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 RKP03217.1 - 7e-23 81.3 0.2 9.9e-22 77.5 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 RKP03217.1 - 4.1e-20 71.6 0.1 7.2e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 RKP03217.1 - 7e-08 32.6 0.0 2.7e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RKP03217.1 - 7.5e-06 26.4 1.0 0.0079 16.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 RKP03217.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 RKP03217.1 - 0.00015 20.6 0.1 0.00015 20.6 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 RKP03217.1 - 0.00016 22.1 0.1 0.21 12.1 0.2 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 RKP03217.1 - 0.00022 20.7 0.2 0.00045 19.7 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 RKP03217.1 - 0.00029 20.6 2.6 0.013 15.1 0.1 3.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 RKP03217.1 - 0.00031 20.8 0.1 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 RKP03217.1 - 0.00047 19.5 0.1 0.00085 18.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 RKP03217.1 - 0.00076 18.8 0.7 0.097 11.9 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 RKP03217.1 - 0.00097 18.3 2.4 0.0011 18.2 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 RKP03217.1 - 0.001 18.4 0.4 0.064 12.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 RKP03217.1 - 0.0019 17.6 0.0 0.038 13.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 RKP03217.1 - 0.054 13.6 0.6 4.3 7.4 0.1 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.17 RKP03217.1 - 0.058 12.6 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 RKP03217.1 - 0.093 12.7 0.3 0.49 10.4 0.0 2.5 2 1 0 2 2 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 RKP03217.1 - 0.11 12.3 0.3 0.25 11.2 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 RKP03217.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pirin PF02678.16 RKP03217.1 - 0.13 12.3 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 1 0 Pirin GIDA PF01134.22 RKP03217.1 - 1.8 7.6 6.0 0.18 10.9 0.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1509 PF07420.11 RKP03218.1 - 0.096 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Ssu72 PF04722.13 RKP03221.1 - 1.5e-80 269.3 0.0 1.6e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GMC_oxred_N PF00732.19 RKP03222.1 - 2.3e-65 220.9 0.0 1e-64 218.8 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 RKP03222.1 - 1.1e-36 126.6 0.3 2e-36 125.7 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 RKP03222.1 - 1.8e-05 24.0 0.1 3.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 RKP03222.1 - 3.1e-05 24.1 0.1 7.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 RKP03222.1 - 0.00018 21.2 0.1 0.00057 19.6 0.1 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 RKP03222.1 - 0.0024 17.2 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 RKP03222.1 - 0.005 16.0 0.2 0.011 14.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 RKP03222.1 - 0.027 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 RKP03222.1 - 0.037 12.7 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 RKP03222.1 - 0.045 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transglut_core PF01841.19 RKP03222.1 - 0.057 13.9 0.1 3.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase-like superfamily Thi4 PF01946.17 RKP03222.1 - 0.18 11.0 0.0 0.39 9.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 RKP03222.1 - 0.19 10.6 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase PITH PF06201.13 RKP03223.1 - 1e-32 113.5 0.0 1.4e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 RKP03223.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin RasGEF PF00617.19 RKP03224.1 - 2.1e-51 174.6 0.0 3.2e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 RKP03224.1 - 9.4e-09 35.5 0.0 4.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Metallophos_2 PF12850.7 RKP03226.1 - 3.2e-21 76.2 0.0 3.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 RKP03226.1 - 0.059 13.9 3.5 0.71 10.3 3.5 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF3224 PF11528.8 RKP03226.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) PCI PF01399.27 RKP03227.1 - 1.5e-16 60.8 0.0 3.9e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 RKP03227.1 - 2.5e-12 46.7 1.5 2.5e-12 46.7 1.5 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Death PF00531.22 RKP03227.1 - 0.05 13.8 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 Death domain DUF1308 PF07000.11 RKP03228.1 - 0.00013 22.0 0.1 0.0024 17.9 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1308) NUDE_C PF04880.13 RKP03228.1 - 0.00094 19.7 8.4 0.014 15.9 5.8 3.1 2 0 0 2 2 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 RKP03228.1 - 0.25 11.8 0.6 0.61 10.6 0.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Ribosomal_L36e PF01158.18 RKP03229.1 - 1.2e-35 121.6 7.1 1.4e-35 121.4 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2207 PF09972.9 RKP03229.1 - 0.03 13.1 0.2 0.032 13.0 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PGAP1 PF07819.13 RKP03231.1 - 0.00067 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 RKP03231.1 - 0.0012 18.1 0.0 0.0032 16.8 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 RKP03231.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 RKP03231.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Pkinase PF00069.25 RKP03232.1 - 1.3e-55 188.6 0.0 1.3e-55 188.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03232.1 - 2.9e-40 138.2 1.6 6.4e-40 137.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase OSR1_C PF12202.8 RKP03232.1 - 0.00016 21.8 0.1 0.00071 19.7 0.1 2.1 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain Med15 PF09606.10 RKP03232.1 - 0.012 14.3 6.2 0.015 14.0 6.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GH114_assoc PF14741.6 RKP03232.1 - 0.036 14.3 0.3 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain Mit_KHE1 PF10173.9 RKP03232.1 - 0.062 13.4 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related UPF0560 PF10577.9 RKP03232.1 - 0.11 11.0 5.5 0.16 10.5 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PIG-P PF08510.12 RKP03233.1 - 5.9e-18 64.9 5.4 1.2e-17 63.9 5.4 1.5 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.12 RKP03233.1 - 0.0056 16.9 0.6 0.0056 16.9 0.6 1.6 2 0 0 2 2 2 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4774 PF15999.5 RKP03233.1 - 0.084 12.7 9.9 0.23 11.3 9.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4774) PUF PF00806.19 RKP03234.1 - 1.1e-20 72.1 0.0 0.0045 16.6 0.0 7.3 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat RRF PF01765.19 RKP03235.1 - 9.2e-29 100.5 2.1 1.2e-28 100.1 2.1 1.1 1 0 0 1 1 1 1 Ribosome recycling factor UreE_C PF05194.12 RKP03235.1 - 0.24 11.9 4.6 0.19 12.2 1.6 2.4 3 1 0 3 3 3 0 UreE urease accessory protein, C-terminal domain TIP49 PF06068.13 RKP03236.1 - 9.6e-159 528.2 1.1 1.6e-158 527.5 1.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RKP03236.1 - 2.7e-27 94.7 1.1 7e-27 93.4 1.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 RKP03236.1 - 2.2e-09 37.2 2.7 1.7e-05 24.6 0.3 3.1 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 RKP03236.1 - 9.6e-08 32.5 4.6 2.2e-05 24.9 0.3 3.3 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 RKP03236.1 - 2.7e-06 26.9 1.0 5.3e-06 26.0 1.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 RKP03236.1 - 9.9e-06 25.6 0.2 0.0074 16.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RKP03236.1 - 9.9e-05 21.8 2.9 0.0023 17.4 1.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RKP03236.1 - 0.00048 20.5 0.6 0.0018 18.7 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 RKP03236.1 - 0.00065 19.3 0.1 0.0016 18.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 RKP03236.1 - 0.00071 19.3 0.6 0.56 9.9 0.4 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 RKP03236.1 - 0.00079 19.8 9.1 0.003 17.9 4.4 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKP03236.1 - 0.0023 18.2 0.6 0.79 10.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 RKP03236.1 - 0.023 14.9 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 RKP03236.1 - 0.031 13.5 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 RKP03236.1 - 0.031 14.3 0.9 0.072 13.1 0.2 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RKP03236.1 - 0.035 13.4 1.7 0.048 12.9 0.5 1.8 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 RKP03236.1 - 0.036 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 RKP03236.1 - 0.039 14.2 1.5 0.078 13.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 RKP03236.1 - 0.042 14.3 1.6 0.15 12.5 1.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 RKP03236.1 - 0.061 12.8 0.4 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_S13 PF00416.22 RKP03236.1 - 0.11 12.9 5.5 0.82 10.1 0.6 3.3 3 0 0 3 3 3 0 Ribosomal protein S13/S18 PIF1 PF05970.14 RKP03236.1 - 0.12 11.5 0.8 8.6 5.4 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.17 RKP03236.1 - 0.14 11.2 0.2 0.37 9.9 0.1 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 RKP03236.1 - 1.2 8.9 5.3 0.55 10.0 1.2 2.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 RKP03236.1 - 1.3 9.0 6.4 3.7 7.5 2.4 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Clat_adaptor_s PF01217.20 RKP03237.1 - 5.5e-52 175.5 1.9 6.6e-52 175.2 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1460 PF07313.12 RKP03237.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) zf-CHY PF05495.12 RKP03238.1 - 1.5e-14 54.2 11.3 3.5e-14 53.0 11.3 1.6 1 1 0 1 1 1 1 CHY zinc finger Zn_ribbon_SprT PF17283.2 RKP03238.1 - 0.00073 19.4 1.4 0.065 13.2 0.1 2.6 2 0 0 2 2 2 1 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RKP03238.1 - 0.0016 18.3 9.4 0.71 9.9 7.3 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 RKP03238.1 - 0.0071 16.4 3.0 0.0071 16.4 3.0 2.5 2 1 0 2 2 2 1 Zinc ribbon domain Cys_rich_KTR PF14205.6 RKP03238.1 - 0.0074 16.1 9.0 0.22 11.3 0.0 2.9 2 1 1 3 3 3 2 Cysteine-rich KTR zf_UBZ PF18439.1 RKP03238.1 - 0.0081 15.7 6.0 2.1 8.0 0.2 3.4 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger NOB1_Zn_bind PF08772.11 RKP03238.1 - 0.009 16.2 1.1 0.009 16.2 1.1 1.9 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-UDP PF14569.6 RKP03238.1 - 0.016 15.3 4.2 0.016 15.3 4.2 1.8 1 1 1 2 2 2 0 Zinc-binding RING-finger SIR2 PF02146.17 RKP03238.1 - 0.036 14.0 2.3 0.049 13.6 2.3 1.2 1 0 0 1 1 1 0 Sir2 family HypA PF01155.19 RKP03238.1 - 0.054 13.5 1.1 0.054 13.5 1.1 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 RKP03238.1 - 0.097 12.9 12.1 16 5.8 12.3 3.0 1 1 1 2 2 2 0 TFIIH C1-like domain RNA_POL_M_15KD PF02150.16 RKP03238.1 - 0.21 11.5 6.9 4.4 7.3 0.1 3.1 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 RKP03238.1 - 0.31 10.9 8.2 2.8 7.9 0.9 3.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 RKP03238.1 - 0.39 10.7 15.5 1 9.4 0.0 3.7 3 1 1 4 4 4 0 zinc-ribbon domain DUF3797 PF12677.7 RKP03238.1 - 1.2 9.0 6.2 3 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Evr1_Alr PF04777.13 RKP03238.1 - 1.6 9.3 6.5 9.1 6.8 6.5 2.0 1 1 0 1 1 1 0 Erv1 / Alr family Zn_Tnp_IS91 PF14319.6 RKP03238.1 - 3.4 7.8 11.8 0.51 10.4 1.3 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-DNL PF05180.12 RKP03238.1 - 4.4 7.3 9.1 8.7 6.4 0.3 3.1 3 0 0 3 3 3 0 DNL zinc finger zinc_ribbon_9 PF14369.6 RKP03238.1 - 8.4 6.7 12.3 2.6 8.4 3.6 2.7 1 1 2 3 3 3 0 zinc-ribbon zf-C2H2_4 PF13894.6 RKP03238.1 - 9.8 7.3 15.1 7.9 7.6 0.5 3.9 3 1 0 3 3 3 0 C2H2-type zinc finger Rrp15p PF07890.12 RKP03239.1 - 7.1e-19 68.5 1.0 7.1e-19 68.5 1.0 4.0 3 2 1 4 4 4 1 Rrp15p CM_2 PF01817.21 RKP03239.1 - 0.061 13.7 0.5 0.061 13.7 0.5 2.6 2 1 0 2 2 2 0 Chorismate mutase type II BUD22 PF09073.10 RKP03239.1 - 0.64 9.3 34.9 0.87 8.9 26.1 2.2 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 RKP03239.1 - 7.2 5.9 28.4 0.5 9.7 17.8 2.2 2 0 0 2 2 2 0 SDA1 NAD_binding_1 PF00175.21 RKP03240.1 - 1.4e-30 106.1 0.0 2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RKP03240.1 - 1.3e-29 102.4 0.0 2e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RKP03240.1 - 3.3e-06 27.3 0.0 0.00018 21.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 RKP03240.1 - 0.0069 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain CAF1 PF04857.20 RKP03241.1 - 4.9e-18 65.4 3.6 1.2e-08 34.5 0.0 3.4 3 1 0 3 3 3 2 CAF1 family ribonuclease FAM75 PF14650.6 RKP03241.1 - 0.83 9.1 5.3 1.1 8.7 5.3 1.1 1 0 0 1 1 1 0 FAM75 family MRP-S26 PF14943.6 RKP03242.1 - 0.0063 16.5 5.9 0.063 13.2 0.2 2.2 2 0 0 2 2 2 2 Mitochondrial ribosome subunit S26 Band_7 PF01145.25 RKP03244.1 - 2.4e-09 37.5 0.3 3.2e-09 37.0 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2993 PF11209.8 RKP03244.1 - 0.018 15.3 0.4 0.028 14.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) LRR_4 PF12799.7 RKP03245.1 - 1.9e-20 72.6 16.7 6.8e-06 26.3 0.1 5.3 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP03245.1 - 4.5e-15 55.2 16.4 2.1e-06 27.4 0.5 5.5 1 1 6 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 RKP03245.1 - 4.1e-12 45.9 2.9 1.7e-08 34.2 0.3 2.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RKP03245.1 - 2.9e-11 42.5 4.6 0.52 10.5 0.1 6.6 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 RKP03245.1 - 0.18 12.5 10.8 1.5e+02 3.5 0.3 7.0 5 3 1 6 6 6 0 Leucine Rich Repeat ZZ PF00569.17 RKP03246.1 - 2.7e-08 33.5 2.9 4.5e-08 32.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 RKP03246.1 - 0.0085 16.3 0.4 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain His_Phos_1 PF00300.22 RKP03247.1 - 4.2e-38 131.0 3.6 4.2e-37 127.7 3.6 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 RKP03247.1 - 0.29 10.4 0.1 0.38 10.1 0.1 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) TPR_2 PF07719.17 RKP03248.1 - 1.2e-07 31.2 1.7 1.3e-05 25.0 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03248.1 - 1.4e-05 24.7 1.1 0.00013 21.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKP03248.1 - 0.00062 19.8 1.0 0.21 11.7 0.1 2.4 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 RKP03248.1 - 0.00062 19.8 1.2 0.027 14.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03248.1 - 0.0012 19.3 0.0 0.0012 19.3 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03248.1 - 0.0027 17.3 0.1 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 RKP03248.1 - 0.02 14.9 0.2 0.22 11.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 RKP03248.1 - 1.8 9.6 0.0 1.8 9.6 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat zinc_ribbon_9 PF14369.6 RKP03249.1 - 2.4 8.5 7.2 22 5.4 2.6 2.7 2 0 0 2 2 2 0 zinc-ribbon Arginosuc_synth PF00764.19 RKP03250.1 - 2.3e-153 511.1 0.0 2.7e-153 510.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 RKP03250.1 - 0.00058 19.4 0.0 0.0009 18.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Peripla_BP_6 PF13458.6 RKP03250.1 - 0.04 13.6 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein tRNA_Me_trans PF03054.16 RKP03250.1 - 0.044 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase ELMO_CED12 PF04727.13 RKP03251.1 - 1.1e-37 129.9 0.2 1.3e-37 129.6 0.2 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family COG5 PF10392.9 RKP03252.1 - 0.16 12.2 0.4 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 RKP03252.1 - 8.5 6.4 9.1 30 4.7 2.2 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4112 PF13430.6 RKP03253.1 - 1.5e-11 44.5 0.0 2.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ion_trans PF00520.31 RKP03254.1 - 4.9e-22 78.3 20.8 6.3e-22 78.0 20.8 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RKP03254.1 - 0.00019 21.3 6.9 0.00019 21.3 6.9 2.8 2 1 0 2 2 2 1 Ion channel Mucin PF01456.17 RKP03254.1 - 1 9.3 5.1 3.4 7.7 5.1 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Lyase_1 PF00206.20 RKP03255.1 - 1.4e-92 310.4 0.0 3.6e-92 309.1 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 RKP03255.1 - 3.3e-23 82.2 0.3 8.4e-23 80.9 0.3 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SAP30_Sin3_bdg PF13867.6 RKP03256.1 - 3.8e-08 33.5 0.1 5.8e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 SPX PF03105.19 RKP03256.1 - 3.5 7.4 8.5 5.5 6.8 8.5 1.2 1 0 0 1 1 1 0 SPX domain ThiF PF00899.21 RKP03257.1 - 3.2e-103 344.3 0.0 4.1e-70 235.9 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 RKP03257.1 - 1.1e-91 307.2 0.0 1.8e-91 306.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 RKP03257.1 - 2.7e-31 108.1 0.0 5.3e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 RKP03257.1 - 1.3e-27 95.8 0.4 2.6e-27 94.8 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 RKP03257.1 - 7.9e-26 90.0 0.9 3.2e-25 88.1 0.9 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Lant_dehydr_N PF04738.13 RKP03257.1 - 0.083 11.0 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus HORMA PF02301.18 RKP03259.1 - 4e-23 82.1 0.1 5.8e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 RKP03259.1 - 0.006 16.4 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial HORMA domain 2 Rota_NSP3 PF01665.16 RKP03259.1 - 0.025 13.7 0.2 0.034 13.3 0.2 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 ATG13 PF10033.9 RKP03259.1 - 0.063 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 DEAD PF00270.29 RKP03260.1 - 1.4e-15 57.5 0.0 3.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP03260.1 - 3.6e-11 43.4 0.1 7.3e-10 39.2 0.0 3.1 3 1 0 3 3 3 1 Helicase conserved C-terminal domain SH3_9 PF14604.6 RKP03261.1 - 2.8e-09 36.7 0.0 4.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP03261.1 - 7.7e-07 28.6 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Phage_holin_2_4 PF16082.5 RKP03261.1 - 0.042 13.6 0.7 0.1 12.3 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4483 PF14825.6 RKP03262.1 - 1.8e-20 73.3 0.1 3.8e-20 72.2 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) AAA_6 PF12774.7 RKP03263.1 - 1.2e-155 517.4 0.0 8.2e-155 514.7 0.0 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKP03263.1 - 9.2e-133 443.2 0.0 9.2e-133 443.2 0.0 2.5 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKP03263.1 - 6.1e-101 337.7 0.0 4.6e-99 331.5 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 RKP03263.1 - 1.5e-90 302.2 2.1 2.6e-90 301.4 1.0 2.1 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 RKP03263.1 - 1.4e-88 296.6 0.0 4.5e-88 294.9 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 RKP03263.1 - 1.2e-72 243.2 0.1 2.2e-66 222.8 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 RKP03263.1 - 6.4e-57 193.1 13.6 1.3e-56 192.2 13.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RKP03263.1 - 7.9e-52 175.4 0.0 1.3e-49 168.2 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKP03263.1 - 1.8e-39 134.5 0.0 1.4e-37 128.4 0.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKP03263.1 - 1.3e-24 86.8 0.0 9.6e-08 32.1 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 RKP03263.1 - 6.6e-16 58.4 0.0 2.1e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 RKP03263.1 - 2.8e-14 53.3 0.0 7.6e-13 48.7 0.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RKP03263.1 - 3.7e-13 50.2 0.1 0.0057 17.1 0.0 6.6 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.6 RKP03263.1 - 2.7e-11 43.9 0.0 0.0006 20.1 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 RKP03263.1 - 4.8e-09 36.7 0.1 0.096 13.1 0.0 4.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RKP03263.1 - 3.8e-07 30.0 0.1 0.36 10.5 0.0 4.2 4 0 0 4 4 3 2 AAA domain Sigma54_activat PF00158.26 RKP03263.1 - 5.1e-07 29.5 0.2 0.005 16.6 0.0 4.4 5 0 0 5 5 4 1 Sigma-54 interaction domain AAA_18 PF13238.6 RKP03263.1 - 1.8e-06 28.5 0.9 0.037 14.6 0.0 4.5 5 0 0 5 5 3 1 AAA domain AAA_19 PF13245.6 RKP03263.1 - 0.00015 22.1 0.1 16 5.8 0.0 4.4 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 RKP03263.1 - 0.00024 21.5 0.1 2 8.9 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.6 RKP03263.1 - 0.00024 21.3 0.4 1.7 8.8 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_14 PF13173.6 RKP03263.1 - 0.00041 20.4 0.0 1.1 9.3 0.0 3.8 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 RKP03263.1 - 0.00069 20.1 0.4 2.1 8.9 0.1 3.4 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.12 RKP03263.1 - 0.00078 19.4 1.4 9.6 6.1 0.0 4.5 4 0 0 4 4 4 0 NACHT domain AAA_29 PF13555.6 RKP03263.1 - 0.00091 18.9 0.2 2.2 8.1 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain HBM PF16591.5 RKP03263.1 - 0.001 18.5 2.6 0.001 18.5 2.6 3.8 4 0 0 4 4 3 1 Helical bimodular sensor domain NTPase_1 PF03266.15 RKP03263.1 - 0.0012 18.8 0.3 6 6.7 0.0 4.1 4 0 0 4 4 4 0 NTPase Sigma54_activ_2 PF14532.6 RKP03263.1 - 0.0013 18.9 0.4 12 6.0 0.0 4.2 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_24 PF13479.6 RKP03263.1 - 0.0022 17.7 0.3 15 5.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 RKP03263.1 - 0.0041 17.2 0.1 0.25 11.4 0.0 3.0 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 RKP03263.1 - 0.0069 16.3 0.0 4.9 7.0 0.1 3.3 3 0 0 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 RKP03263.1 - 0.023 13.9 0.1 1.1 8.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 RKP03263.1 - 0.024 14.0 2.2 2 7.7 0.0 3.3 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RKP03263.1 - 0.036 13.2 0.5 11 5.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF815) TsaE PF02367.17 RKP03263.1 - 0.043 13.8 1.8 4.2 7.4 0.0 3.9 5 0 0 5 5 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 RKP03263.1 - 0.069 12.8 5.0 3.9 7.0 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain STI1 PF17830.1 RKP03263.1 - 0.13 12.2 0.4 0.53 10.3 0.4 2.1 1 0 0 1 1 1 0 STI1 domain ATPase_2 PF01637.18 RKP03263.1 - 0.13 12.2 0.0 1.6 8.6 0.0 2.9 3 1 0 3 3 1 0 ATPase domain predominantly from Archaea Hpr_kinase_C PF07475.12 RKP03263.1 - 0.13 11.8 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Roc PF08477.13 RKP03263.1 - 0.14 12.4 0.1 36 4.6 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 RKP03263.1 - 0.78 9.3 5.8 3.1 7.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 RKP03263.1 - 1.7 8.4 4.5 4.5 7.0 0.0 3.5 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_2 PF07724.14 RKP03264.1 - 5.5e-38 130.8 0.0 8.8e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 RKP03264.1 - 6e-16 59.1 0.0 9.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 RKP03264.1 - 4.7e-09 36.2 0.3 1.1e-07 31.9 0.0 2.7 2 1 1 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 RKP03264.1 - 1.5e-07 31.8 0.3 3.8e-06 27.2 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 RKP03264.1 - 2.6e-07 30.7 0.0 1.1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 RKP03264.1 - 0.00033 20.1 0.2 0.047 13.1 0.1 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 RKP03264.1 - 0.00046 20.6 2.1 0.0012 19.3 0.7 2.3 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 RKP03264.1 - 0.00052 20.0 0.0 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain MCM PF00493.23 RKP03264.1 - 0.0015 17.7 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_30 PF13604.6 RKP03264.1 - 0.0026 17.5 0.2 0.0049 16.6 0.2 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RKP03264.1 - 0.0033 17.2 0.5 0.022 14.5 0.5 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 RKP03264.1 - 0.0036 16.4 0.1 0.0081 15.2 0.1 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 RKP03264.1 - 0.0056 16.4 0.5 0.36 10.5 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AIRS_C PF02769.22 RKP03264.1 - 0.006 16.7 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain DEAD PF00270.29 RKP03264.1 - 0.0065 16.2 1.4 2.5 7.8 0.1 3.1 2 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_14 PF13173.6 RKP03264.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 RKP03264.1 - 0.022 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2398 PF09661.10 RKP03264.1 - 0.03 13.6 0.2 0.085 12.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) AAA_7 PF12775.7 RKP03264.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 RKP03264.1 - 0.039 14.5 0.0 0.073 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RKP03264.1 - 0.046 13.5 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 RKP03264.1 - 0.052 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RKP03264.1 - 0.062 13.2 1.1 8.6 6.2 0.0 2.7 2 1 1 3 3 3 0 NTPase IstB_IS21 PF01695.17 RKP03264.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 RKP03264.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 RKP03264.1 - 0.11 12.2 0.1 0.43 10.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 RKP03264.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 RKP03264.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IPT PF01745.16 RKP03264.1 - 0.17 11.2 0.1 0.41 10.0 0.1 1.5 1 0 0 1 1 1 0 Isopentenyl transferase ATPase_2 PF01637.18 RKP03264.1 - 0.2 11.5 0.0 0.75 9.7 0.0 1.8 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 RKP03264.1 - 0.23 11.9 0.0 0.41 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sybindin PF04099.12 RKP03265.1 - 1.6e-23 83.2 0.0 1.9e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 RKP03265.1 - 0.002 18.3 0.2 0.0028 17.8 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region KaiA PF07688.12 RKP03265.1 - 0.06 13.5 0.1 0.086 13.0 0.1 1.2 1 0 0 1 1 1 0 KaiA C-terminal domain zf-Tim10_DDP PF02953.15 RKP03266.1 - 1e-19 69.9 3.2 1e-19 69.9 3.2 1.9 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Tam41_Mmp37 PF09139.11 RKP03266.1 - 0.041 13.3 0.3 0.043 13.3 0.3 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial CDC50 PF03381.15 RKP03269.1 - 2.4e-68 230.7 0.0 2.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sad1_UNC PF07738.13 RKP03270.1 - 2.3e-14 53.5 0.0 1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal HemY_N PF07219.13 RKP03270.1 - 0.016 15.4 0.0 0.016 15.4 0.0 4.8 5 1 0 5 5 5 0 HemY protein N-terminus DUF445 PF04286.12 RKP03270.1 - 0.061 13.1 6.3 0.081 12.7 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4834 PF16118.5 RKP03270.1 - 0.11 13.4 0.1 1.3 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Sec6 PF06046.13 RKP03270.1 - 0.29 9.5 1.9 0.54 8.5 1.9 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec6 DUF3819 PF12842.7 RKP03270.1 - 8.5 6.3 14.4 0.58 10.1 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) Mis14 PF08641.12 RKP03270.1 - 9.6 6.5 11.0 4.4 7.6 1.4 3.2 2 1 1 3 3 3 0 Kinetochore protein Mis14 like Ribosomal_S8 PF00410.19 RKP03271.1 - 4.2e-20 72.0 0.0 3.7e-19 68.9 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_60s PF00428.19 RKP03272.1 - 2e-23 82.8 8.3 2.5e-23 82.5 8.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein FTCD_C PF04961.12 RKP03272.1 - 0.7 9.6 5.4 0.8 9.4 2.4 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF3824 PF12868.7 RKP03272.1 - 2.9 8.6 4.8 3.9 8.1 4.8 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) ASH PF15780.5 RKP03273.1 - 1.9e-30 105.0 32.4 0.012 15.8 0.0 18.0 19 1 0 19 19 19 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RKP03273.1 - 3.5e-10 39.8 0.3 0.98 9.5 0.0 9.0 9 1 0 9 9 9 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 RKP03273.1 - 8.4e-06 25.9 0.9 28 4.9 0.0 7.3 7 0 0 7 7 7 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 RKP03273.1 - 0.00027 20.7 0.1 9.7 6.1 0.0 6.6 8 0 0 8 8 8 1 MSP (Major sperm protein) domain MYCBPAP PF14646.6 RKP03273.1 - 0.00046 19.2 0.7 6.1 5.7 0.0 5.3 7 0 0 7 7 7 1 MYCBP-associated protein family TMEM131_like PF12371.8 RKP03273.1 - 0.0016 18.6 12.4 43 4.5 0.0 9.5 11 0 0 11 11 11 0 Transmembrane protein 131-like CBFD_NFYB_HMF PF00808.23 RKP03274.1 - 6e-19 68.1 0.2 9.6e-19 67.4 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RKP03274.1 - 0.012 15.9 0.1 0.038 14.4 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 RKP03274.1 - 0.046 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TAFII28 PF04719.14 RKP03274.1 - 0.098 12.8 0.1 0.25 11.4 0.1 1.8 1 1 0 1 1 1 0 hTAFII28-like protein conserved region HTH_IclR PF09339.10 RKP03274.1 - 0.14 12.0 0.0 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Coatomer_WDAD PF04053.14 RKP03275.1 - 2.6e-105 353.0 0.0 5e-105 352.1 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 RKP03275.1 - 5.1e-97 325.2 0.0 7.8e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 RKP03275.1 - 7.7e-44 146.8 14.7 3.2e-08 34.1 0.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03275.1 - 1.6e-10 41.2 1.5 0.0033 17.7 0.0 4.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP03275.1 - 0.013 14.2 3.4 2.2 6.9 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 ENTH PF01417.20 RKP03275.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 ENTH domain T4_Rnl2_C PF18043.1 RKP03275.1 - 0.18 11.9 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal Prok-RING_1 PF14446.6 RKP03275.1 - 0.38 10.7 1.9 0.41 10.6 0.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHM7_ext PF12621.8 RKP03276.1 - 0.025 14.7 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter IFT46_B_C PF12317.8 RKP03278.1 - 3.6e-66 222.9 0.0 4.5e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal ACC_epsilon PF13822.6 RKP03278.1 - 3 8.6 7.0 7.9 7.2 0.8 3.4 2 1 1 3 3 3 0 Acyl-CoA carboxylase epsilon subunit AAA PF00004.29 RKP03279.1 - 1e-39 136.0 0.0 1.3e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKP03279.1 - 0.00014 22.3 0.6 0.0027 18.1 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP03279.1 - 0.0027 18.0 0.5 0.055 13.7 0.4 2.1 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 RKP03279.1 - 0.0048 16.1 0.0 0.0067 15.7 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 RKP03279.1 - 0.0067 16.4 0.0 0.0087 16.1 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 RKP03279.1 - 0.0072 15.9 0.6 2.1 7.9 0.3 2.1 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.22 RKP03279.1 - 0.03 14.7 0.0 0.064 13.6 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 RKP03279.1 - 0.034 14.2 0.1 0.089 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RKP03279.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IPT PF01745.16 RKP03279.1 - 0.053 12.9 0.1 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 Isopentenyl transferase RuvB_N PF05496.12 RKP03279.1 - 0.061 13.1 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 RKP03279.1 - 0.069 13.1 0.1 5.6 6.9 0.2 2.1 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 RKP03279.1 - 0.13 12.7 0.2 0.28 11.6 0.2 1.6 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 RKP03279.1 - 0.14 12.7 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 RKP03279.1 - 0.14 11.5 0.0 10 5.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 RKP03279.1 - 0.16 12.2 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RKP03279.1 - 0.17 12.0 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RKP03279.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 RKP03279.1 - 0.25 10.7 0.0 0.51 9.6 0.0 1.4 2 0 0 2 2 2 0 KaiC Mito_carr PF00153.27 RKP03280.1 - 2.5e-27 94.6 5.6 1.3e-13 50.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Glycos_transf_2 PF00535.26 RKP03281.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 CLASP_N PF12348.8 RKP03282.1 - 2.4e-30 105.8 0.0 3.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 RKP03282.1 - 0.00064 20.1 14.6 0.0021 18.4 2.7 4.7 3 2 1 4 4 4 2 HEAT repeats CHCH PF06747.13 RKP03283.1 - 2.7e-06 27.4 3.6 5.6e-06 26.3 3.6 1.6 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 RKP03283.1 - 0.0038 17.6 1.2 0.0048 17.3 1.2 1.2 1 0 0 1 1 1 1 GCK domain Voldacs PF03517.13 RKP03283.1 - 0.0071 16.5 1.2 0.008 16.3 1.2 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling TPH PF13868.6 RKP03284.1 - 0.0009 17.8 88.7 0.0009 17.8 88.7 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain HSP90 PF00183.18 RKP03285.1 - 2.4e-159 531.6 0.1 3.3e-159 531.1 0.1 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 RKP03285.1 - 1.7e-10 41.4 0.0 3.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RKP03285.1 - 1.7e-10 40.9 0.0 4.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 RKP03286.1 - 2.1e-31 107.5 14.3 6.4e-07 30.0 0.2 10.9 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03286.1 - 2.5e-12 46.9 0.0 0.00089 19.5 0.0 5.8 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP03286.1 - 0.0033 16.4 0.4 5.5 5.8 0.0 3.6 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RKP03286.1 - 0.042 13.2 0.0 4.7 6.4 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Nbas_N PF15492.6 RKP03286.1 - 0.051 12.9 0.2 0.22 10.8 0.1 2.1 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 RKP03286.1 - 0.28 11.2 2.2 0.6 10.1 0.1 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat tRNA-synt_2d PF01409.20 RKP03287.1 - 2.1e-89 299.3 0.0 2.6e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 RKP03287.1 - 2e-09 37.2 0.0 1.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 RKP03287.1 - 2e-09 37.6 0.1 4.8e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA-synt_2b PF00587.25 RKP03287.1 - 0.00061 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 RKP03287.1 - 0.0024 17.0 0.2 0.018 14.1 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) TAP42 PF04177.12 RKP03288.1 - 6.1e-78 262.1 3.3 6.9e-78 262.0 3.3 1.0 1 0 0 1 1 1 1 TAP42-like family Adaptin_binding PF10199.9 RKP03288.1 - 0.17 12.5 1.7 0.3 11.7 1.7 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Dus PF01207.17 RKP03290.1 - 1.6e-48 165.4 0.0 1.2e-41 142.8 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 RKP03290.1 - 0.00065 19.2 0.1 0.0014 18.2 0.1 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF5419 PF17441.2 RKP03290.1 - 0.047 13.8 0.4 0.13 12.3 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5419) Ras PF00071.22 RKP03291.1 - 1.4e-34 119.0 0.3 1.8e-34 118.7 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP03291.1 - 2.4e-25 89.1 0.1 4.1e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP03291.1 - 7.3e-08 32.1 0.1 9.5e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKP03291.1 - 3.1e-07 30.0 0.2 4e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 RKP03291.1 - 0.00093 18.8 0.1 0.0036 16.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DLIC PF05783.11 RKP03291.1 - 0.0093 14.8 0.3 2.4 6.9 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 RKP03291.1 - 0.02 14.3 0.0 2.3 7.6 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein G-alpha PF00503.20 RKP03291.1 - 0.054 12.6 1.1 0.11 11.6 0.3 2.0 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 RKP03291.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_L5 PF00281.19 RKP03293.1 - 7.5e-21 74.2 0.0 4.8e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 RKP03293.1 - 4.4e-20 71.6 0.0 6.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HMGL-like PF00682.19 RKP03294.1 - 5e-59 200.0 0.0 5.8e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Aldolase_II PF00596.21 RKP03294.1 - 0.023 14.7 0.8 0.039 13.9 0.8 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain fn3_2 PF16893.5 RKP03295.1 - 5.3e-25 87.4 0.0 9.4e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 RKP03295.1 - 4.8e-24 84.0 0.1 7.6e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 RKP03295.1 - 7.9e-18 64.2 0.0 1.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 RKP03295.1 - 1.8e-11 44.3 0.0 2.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 RKP03295.1 - 2e-06 28.1 0.0 6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 RKP03295.1 - 4.6e-05 23.6 0.0 9.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 RKP03295.1 - 0.00079 19.8 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain TIG PF01833.24 RKP03295.1 - 0.16 12.1 0.6 3.6 7.7 0.0 3.0 2 1 1 3 3 3 0 IPT/TIG domain RabGAP-TBC PF00566.18 RKP03296.1 - 2.2e-39 135.3 0.0 3.2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 RKP03296.1 - 1.4e-05 24.6 0.9 5.1e-05 22.9 0.9 2.0 1 0 0 1 1 1 1 EF-hand domain GRAM PF02893.20 RKP03296.1 - 0.00013 21.8 0.0 0.9 9.4 0.0 3.4 3 1 0 3 3 3 2 GRAM domain EF-hand_1 PF00036.32 RKP03296.1 - 0.0015 17.9 0.5 0.0015 17.9 0.5 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RKP03296.1 - 0.0031 17.9 0.0 0.0079 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair RRM_1 PF00076.22 RKP03297.1 - 1.2e-19 69.9 0.0 3.2e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKP03297.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 RKP03297.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 RKP03297.1 - 0.24 11.3 0.0 1.9 8.4 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif CN_hydrolase PF00795.22 RKP03298.1 - 5.8e-13 48.8 0.0 1.2e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase CHCH PF06747.13 RKP03299.1 - 2.1e-05 24.5 5.7 2.1e-05 24.5 5.7 2.5 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 RKP03299.1 - 0.015 15.3 11.6 0.072 13.1 3.8 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 RKP03299.1 - 0.05 13.9 11.9 1.7 9.0 0.3 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 RKP03299.1 - 1.1 9.4 14.7 1.4 9.0 0.4 3.1 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 RKP03299.1 - 1.2 9.5 15.2 0.34 11.2 6.2 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 RKP03299.1 - 4.2 7.8 12.5 2.5 8.5 6.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) DUF3306 PF11748.8 RKP03301.1 - 0.34 11.8 0.1 0.34 11.8 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3306) SDA1 PF05285.12 RKP03303.1 - 3.8e-05 23.3 15.5 5.9e-05 22.7 15.5 1.2 1 0 0 1 1 1 1 SDA1 Myb_DNA-binding PF00249.31 RKP03303.1 - 0.0043 17.2 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nop14 PF04147.12 RKP03303.1 - 0.024 12.9 21.0 0.036 12.3 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RKP03303.1 - 0.076 12.4 21.5 0.17 11.2 21.5 1.6 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 RKP03303.1 - 0.19 10.3 12.7 0.28 9.7 12.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Serglycin PF04360.12 RKP03303.1 - 0.83 9.6 6.4 1.8 8.5 6.4 1.5 1 0 0 1 1 1 0 Serglycin PPP4R2 PF09184.11 RKP03303.1 - 9.8 5.7 22.2 17 4.9 22.2 1.2 1 0 0 1 1 1 0 PPP4R2 YL1 PF05764.13 RKP03303.1 - 9.8 6.2 18.3 22 5.0 18.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Proteasome PF00227.26 RKP03304.1 - 4.3e-49 166.6 0.1 4.8e-49 166.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Aminotran_3 PF00202.21 RKP03304.1 - 0.056 12.1 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Flavodoxin_1 PF00258.25 RKP03304.1 - 0.085 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin WD40 PF00400.32 RKP03305.1 - 9.8e-08 32.6 0.9 0.11 13.4 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03305.1 - 0.00059 20.1 0.9 0.89 9.9 0.0 4.2 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2057 PF09829.9 RKP03305.1 - 0.36 11.0 1.3 0.6 10.2 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) WD40 PF00400.32 RKP03307.1 - 4.9e-08 33.5 1.7 0.017 16.0 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03307.1 - 0.18 12.1 0.0 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Selenoprotein_S PF06936.11 RKP03307.1 - 1.8 8.3 6.0 26 4.5 2.6 2.7 2 0 0 2 2 2 0 Selenoprotein S (SelS) LRR_6 PF13516.6 RKP03308.1 - 3.8e-08 32.8 8.2 0.41 10.8 0.2 6.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 RKP03308.1 - 0.00078 19.8 1.1 2.8 8.5 0.1 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) VP40 PF07447.12 RKP03308.1 - 0.051 12.7 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Matrix protein VP40 LRR_8 PF13855.6 RKP03308.1 - 0.2 11.4 1.5 14 5.5 0.0 3.6 3 1 0 3 3 3 0 Leucine rich repeat Ribosomal_S13_N PF08069.12 RKP03309.1 - 2.6e-29 101.1 0.9 5.3e-29 100.0 0.9 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 RKP03309.1 - 2.5e-14 53.2 0.1 3.5e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 RKP03309.1 - 0.0062 16.5 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 'Paired box' domain DEAD PF00270.29 RKP03311.1 - 1.8e-43 148.3 0.0 6e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP03311.1 - 5.1e-29 100.8 0.0 1.4e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 RKP03311.1 - 4.2e-14 52.6 0.0 1.4e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 RKP03311.1 - 0.029 13.7 0.0 0.029 13.7 0.0 2.7 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 RKP03311.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DHHC PF01529.20 RKP03312.1 - 1.7e-33 115.6 11.6 2.7e-33 114.9 11.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase TarH PF02203.15 RKP03312.1 - 0.21 11.5 1.2 0.35 10.8 1.2 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue PRA1 PF03208.19 RKP03312.1 - 0.91 9.1 7.5 1.8 8.2 7.5 1.4 1 0 0 1 1 1 0 PRA1 family protein Pkinase PF00069.25 RKP03313.1 - 6.7e-56 189.6 0.0 7.7e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03313.1 - 1.2e-44 152.5 0.0 1.6e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP03313.1 - 0.00072 18.4 0.0 0.00097 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 RKP03313.1 - 0.0024 17.3 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKP03313.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Peptidase_C2 PF00648.21 RKP03315.1 - 5.1e-22 78.3 0.0 2.7e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 RKP03315.1 - 6.6e-05 23.2 0.0 0.00015 22.0 0.0 1.6 1 1 0 1 1 1 1 Calpain large subunit, domain III UCH PF00443.29 RKP03316.1 - 8.6e-44 150.0 0.0 1.1e-43 149.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP03316.1 - 4.6e-08 33.0 0.0 0.00031 20.4 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CS PF04969.16 RKP03316.1 - 0.00012 23.1 0.0 0.00021 22.3 0.0 1.4 1 0 0 1 1 1 1 CS domain WD40 PF00400.32 RKP03317.1 - 0.00017 22.3 7.7 11 7.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03317.1 - 0.00077 19.7 0.0 0.35 11.2 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 RKP03317.1 - 0.0029 17.6 9.1 0.0066 16.5 9.1 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 OmpH PF03938.14 RKP03317.1 - 1.4 9.3 11.3 2.6 8.4 11.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Siah-Interact_N PF09032.11 RKP03317.1 - 1.6 9.1 7.0 4 7.8 7.0 1.7 1 0 0 1 1 1 0 Siah interacting protein, N terminal Spt20 PF12090.8 RKP03317.1 - 4.6 6.8 9.2 7.2 6.1 9.2 1.2 1 0 0 1 1 1 0 Spt20 family API5 PF05918.11 RKP03317.1 - 6.9 5.4 6.2 9.7 4.9 6.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NRIP1_repr_3 PF15689.5 RKP03318.1 - 0.2 12.0 1.3 0.42 10.9 0.4 2.1 1 1 1 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Host_attach PF10116.9 RKP03318.1 - 0.57 10.7 4.7 0.32 11.5 2.1 1.9 1 1 1 2 2 2 0 Protein required for attachment to host cells TFIIA PF03153.13 RKP03319.1 - 7.9 6.4 8.5 10 6.0 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PXA PF02194.15 RKP03320.1 - 1.8e-25 90.0 0.3 5.5e-25 88.4 0.3 1.9 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 RKP03320.1 - 1.7e-19 70.4 0.3 5.2e-19 68.9 0.3 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal C2 PF00168.30 RKP03320.1 - 2.8e-09 37.2 0.0 7.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain PX PF00787.24 RKP03320.1 - 7.9e-07 29.1 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 RKP03320.1 - 0.0016 18.7 0.0 0.13 12.6 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain LIAS_N PF16881.5 RKP03321.1 - 3.6e-22 78.8 0.1 1.1e-21 77.3 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 RKP03321.1 - 5.2e-12 46.4 0.1 9.4e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Propep_M14 PF02244.16 RKP03321.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide DUF3306 PF11748.8 RKP03321.1 - 1 10.2 8.6 0.26 12.2 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) TetR_C_24 PF17932.1 RKP03322.1 - 0.32 11.3 1.6 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HlyIII PF03006.20 RKP03323.1 - 4.6e-54 183.5 16.8 5.9e-54 183.2 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4220 PF13968.6 RKP03323.1 - 0.092 12.1 0.9 0.14 11.5 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Nucleopor_Nup85 PF07575.13 RKP03323.1 - 0.26 9.8 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin DUF962 PF06127.11 RKP03323.1 - 0.57 10.3 3.7 1.3 9.1 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Cyclin PF08613.11 RKP03324.1 - 0.39 11.1 6.2 5 7.5 6.2 2.8 1 1 0 1 1 1 0 Cyclin Spt20 PF12090.8 RKP03324.1 - 1.4 8.5 19.6 0.39 10.3 15.4 2.0 2 0 0 2 2 2 0 Spt20 family Pyridoxal_deC PF00282.19 RKP03325.1 - 1.4e-62 211.6 0.0 1.8e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4641 PF15483.6 RKP03325.1 - 0.035 13.2 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Hydrophobin PF01185.18 RKP03326.1 - 0.00011 22.8 7.4 0.00021 21.9 7.3 1.5 1 1 0 1 1 1 1 Fungal hydrophobin Syja_N PF02383.18 RKP03327.1 - 1.8e-76 257.5 0.0 2.4e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Mito_carr PF00153.27 RKP03328.1 - 2.1e-71 235.9 0.1 2.2e-25 88.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 RKP03328.1 - 2.5e-17 61.1 1.0 0.00024 20.4 0.0 5.5 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 RKP03328.1 - 2.7e-15 56.5 0.8 0.00029 21.2 0.0 4.2 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RKP03328.1 - 1.4e-14 52.7 1.4 0.0023 17.7 0.2 5.8 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 RKP03328.1 - 2.5e-13 49.7 3.3 0.0081 16.0 0.0 5.8 5 1 0 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 RKP03328.1 - 0.00016 21.0 0.2 0.76 9.4 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RKP03328.1 - 0.007 16.7 0.1 14 6.1 0.0 3.5 2 1 0 2 2 2 2 EF-hand domain Dynein_attach_N PF15867.5 RKP03328.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus P30 PF07390.11 RKP03328.1 - 0.21 11.7 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Mycoplasma P30 protein TMF_TATA_bd PF12325.8 RKP03329.1 - 8.4e-19 67.9 6.2 8.4e-19 67.9 6.2 6.5 3 2 3 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 RKP03329.1 - 1.3e-13 50.8 7.8 1.3e-13 50.8 7.8 6.8 6 1 2 8 8 8 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 RKP03329.1 - 0.0031 17.8 4.7 0.0031 17.8 4.7 5.4 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 RKP03329.1 - 0.014 15.2 0.0 4.3 7.3 0.0 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.21 RKP03329.1 - 0.039 14.1 0.6 0.039 14.1 0.6 3.2 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 RKP03329.1 - 3 8.2 7.8 23 5.4 0.7 4.4 4 0 0 4 4 4 0 TSC-22/dip/bun family Nup88 PF10168.9 RKP03329.1 - 7.7 4.2 26.0 2.9 5.6 0.4 2.3 2 0 0 2 2 2 0 Nuclear pore component Fungal_TACC PF12709.7 RKP03329.1 - 8.7 6.9 13.4 3.5 8.1 2.1 4.2 3 1 0 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins LSM PF01423.22 RKP03330.1 - 1e-21 76.4 0.0 1.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKP03330.1 - 0.0015 18.6 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain HSA PF07529.13 RKP03332.1 - 2.1e-07 31.2 0.4 2.1e-07 31.2 0.4 3.6 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 RKP03332.1 - 0.00092 19.4 0.4 0.0017 18.5 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2722 PF10846.8 RKP03332.1 - 0.0034 16.4 13.1 0.0034 16.4 13.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Myb_DNA-binding PF00249.31 RKP03332.1 - 0.0095 16.1 0.4 0.022 15.0 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Septin PF00735.18 RKP03333.1 - 6.6e-108 360.3 0.0 9.1e-108 359.8 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RKP03333.1 - 2.2e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKP03333.1 - 1.1e-05 25.1 0.0 0.00039 20.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKP03333.1 - 4.1e-05 23.5 0.2 0.00054 19.9 0.2 2.4 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 RKP03333.1 - 4.8e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Pox_A32 PF04665.12 RKP03333.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 RKP03333.1 - 0.00016 21.9 0.0 0.00047 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 RKP03333.1 - 0.00046 19.6 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 RKP03333.1 - 0.0018 18.7 1.3 0.008 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 RKP03333.1 - 0.0029 17.8 0.1 0.0087 16.3 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 RKP03333.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.6 RKP03333.1 - 0.011 15.3 1.7 0.11 12.1 0.1 3.1 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RKP03333.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 RKP03333.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RKP03333.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 RKP03333.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RKP03333.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 RKP03333.1 - 0.082 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 RKP03333.1 - 0.1 12.3 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 RKP03333.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 RKP03333.1 - 0.18 11.5 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RKP03333.1 - 0.37 10.8 3.5 4.7 7.2 0.1 2.7 2 1 1 3 3 2 0 Dynamin family 14-3-3 PF00244.20 RKP03334.1 - 5.6e-108 359.6 5.8 6.6e-108 359.3 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 RKP03334.1 - 0.34 9.3 3.8 0.58 8.5 3.8 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 PQ-loop PF04193.14 RKP03335.1 - 4.1e-07 29.7 4.4 0.00027 20.6 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat KleE PF17394.2 RKP03336.1 - 0.13 12.4 1.6 0.14 12.4 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Pga1 PF10333.9 RKP03336.1 - 0.26 11.1 0.1 0.89 9.4 0.0 1.7 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator UQ_con PF00179.26 RKP03337.1 - 3.2e-40 137.0 0.0 4e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 RKP03337.1 - 5.7e-10 38.9 0.2 1.3e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 RKP03337.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CUE PF02845.16 RKP03337.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 CUE domain Heme_oxygenase PF01126.20 RKP03338.1 - 6.4e-30 104.5 6.1 1.1e-19 71.0 0.2 2.9 3 0 0 3 3 3 2 Heme oxygenase TetR_C_28 PF17937.1 RKP03338.1 - 3.3 8.2 20.9 0.052 14.0 6.5 3.7 3 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain WD40 PF00400.32 RKP03339.1 - 1.2e-12 48.1 4.7 0.098 13.6 0.2 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03339.1 - 0.0015 18.8 0.2 2.5 8.5 0.1 3.8 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ASH PF15780.5 RKP03340.1 - 1.6e-05 25.0 0.0 1 9.6 0.1 5.2 8 0 0 8 8 8 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 RKP03340.1 - 0.00012 22.2 0.0 0.0016 18.5 0.0 2.9 3 0 0 3 3 3 1 Flagellar-associated PapD-like NIF3 PF01784.18 RKP03341.1 - 7.7e-69 232.0 0.0 9.4e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RasGAP PF00616.19 RKP03342.1 - 4.6e-50 170.2 0.2 1.6e-49 168.5 0.2 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 RKP03342.1 - 1.5e-42 145.0 5.1 1.5e-42 145.0 5.1 2.8 2 1 1 3 3 3 1 RasGAP C-terminus CH PF00307.31 RKP03342.1 - 4.8e-15 55.7 0.0 1.4e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 RKP03342.1 - 1.5e-07 30.6 25.8 0.001 18.7 1.9 5.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif Spore_III_AB PF09548.10 RKP03342.1 - 0.035 14.2 6.7 4.1 7.5 0.0 4.1 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) PDE4_UCR PF18100.1 RKP03342.1 - 3.8 8.2 5.5 4.3 8.0 2.6 2.7 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) TRAUB PF08164.12 RKP03343.1 - 3.6e-26 91.5 0.2 3.6e-26 91.5 0.2 2.2 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 RKP03343.1 - 2.6e-10 41.1 0.4 2.6e-10 41.1 0.4 2.9 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor SH3_9 PF14604.6 RKP03345.1 - 5.3e-06 26.2 0.0 8.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAN_1 PF00024.26 RKP03345.1 - 0.00023 21.1 2.3 0.24 11.4 0.1 3.1 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 RKP03345.1 - 0.00062 19.6 11.3 0.0082 16.0 0.5 3.2 3 0 0 3 3 3 2 PAN domain SH3_1 PF00018.28 RKP03345.1 - 0.0018 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Amnionless PF14828.6 RKP03345.1 - 0.048 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 RKP03345.1 - 0.18 12.7 0.0 0.38 11.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ABC_membrane_2 PF06472.15 RKP03347.1 - 1.4e-98 329.6 3.0 1.8e-98 329.2 3.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RKP03347.1 - 9.8e-17 61.8 0.0 2.7e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 RKP03347.1 - 0.0011 19.6 0.1 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 RKP03347.1 - 0.0012 18.7 0.0 0.0066 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 RKP03347.1 - 0.0019 18.0 0.1 0.026 14.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 RKP03347.1 - 0.0058 16.1 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Cyto_heme_lyase PF01265.17 RKP03347.1 - 0.0068 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase AAA_29 PF13555.6 RKP03347.1 - 0.0082 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbmA_BacA PF05992.12 RKP03347.1 - 0.022 14.2 0.2 0.032 13.7 0.2 1.3 1 0 0 1 1 1 0 SbmA/BacA-like family AAA_27 PF13514.6 RKP03347.1 - 0.11 12.1 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.6 RKP03347.1 - 0.11 12.9 0.3 0.33 11.4 0.3 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 RKP03347.1 - 0.36 10.6 1.6 1 9.2 1.6 1.7 1 0 0 1 1 1 0 Septum formation initiator Mpp10 PF04006.12 RKP03348.1 - 7.7e-109 364.9 50.3 3.1e-107 359.6 50.3 2.3 1 1 0 1 1 1 1 Mpp10 protein DUF1382 PF07131.11 RKP03348.1 - 0.069 13.2 1.4 19 5.3 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) YabA PF06156.13 RKP03348.1 - 0.63 10.7 2.2 8.6 7.1 0.0 3.5 3 1 0 3 3 3 0 Initiation control protein YabA DIOX_N PF14226.6 RKP03349.1 - 4.8e-06 27.3 0.0 8.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RKP03349.1 - 0.00031 21.2 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PseudoU_synth_1 PF01416.20 RKP03350.1 - 2.8e-13 50.3 0.0 3.9e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase ADH_zinc_N PF00107.26 RKP03351.1 - 2.2e-17 63.3 3.3 2.2e-17 63.3 3.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 RKP03351.1 - 5.6e-16 59.8 0.8 1.2e-15 58.8 0.4 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 RKP03351.1 - 1.7e-10 40.7 0.0 3.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 RKP03351.1 - 0.0024 17.3 2.7 0.0024 17.3 2.7 1.8 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N_2 PF16884.5 RKP03351.1 - 0.0032 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase CUE PF02845.16 RKP03353.1 - 3.9e-08 32.8 0.0 6.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 RKP03353.1 - 0.0029 17.2 4.4 0.0045 16.6 4.4 1.3 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) EamA PF00892.20 RKP03354.1 - 2.9e-11 43.7 34.5 5.9e-07 29.7 6.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 RKP03354.1 - 0.0062 16.6 0.5 0.0062 16.6 0.5 2.6 3 0 0 3 3 3 1 Putative transmembrane family 234 GpcrRhopsn4 PF10192.9 RKP03354.1 - 0.021 14.2 0.8 0.021 14.2 0.8 2.6 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain zf-RING_2 PF13639.6 RKP03355.1 - 1.8e-08 34.6 2.5 2.8e-08 34.0 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RKP03355.1 - 8.3e-06 26.0 1.8 1.5e-05 25.2 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 RKP03355.1 - 0.00039 20.2 3.1 0.00063 19.5 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKP03355.1 - 0.00045 19.9 0.7 0.00078 19.1 0.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RKP03355.1 - 0.00061 19.6 2.0 0.0009 19.1 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP03355.1 - 0.0018 18.2 1.9 0.0027 17.6 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RKP03355.1 - 0.0018 18.3 0.9 0.0031 17.5 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RKP03355.1 - 0.0083 16.0 1.5 0.012 15.4 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 RKP03355.1 - 0.026 14.6 0.6 0.038 14.1 0.6 1.2 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 RKP03355.1 - 0.028 14.0 1.7 0.057 13.1 1.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 RKP03355.1 - 0.067 13.1 2.1 0.12 12.3 2.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF5437 PF17505.2 RKP03355.1 - 0.11 12.5 0.3 0.27 11.3 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5437) zf-Di19 PF05605.12 RKP03355.1 - 0.12 12.7 0.5 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.6 RKP03355.1 - 0.14 12.1 3.0 0.31 11.0 0.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF2614 PF11023.8 RKP03355.1 - 0.19 11.9 3.7 3.4 7.8 0.1 3.2 1 1 2 3 3 3 0 Zinc-ribbon containing domain DUF3797 PF12677.7 RKP03355.1 - 0.25 11.3 1.8 0.4 10.6 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) FANCL_C PF11793.8 RKP03355.1 - 0.35 11.1 3.7 11 6.2 3.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 RKP03355.1 - 0.47 10.4 2.5 0.87 9.5 2.5 1.5 1 1 0 1 1 1 0 PHD-finger C2-C2_1 PF11618.8 RKP03356.1 - 2.6e-05 24.3 0.0 0.016 15.3 0.0 2.7 2 0 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 Arg_repressor PF01316.21 RKP03356.1 - 0.095 12.5 0.9 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain TFIIE-A_C PF11521.8 RKP03356.1 - 9.2 6.6 11.9 11 6.4 4.9 3.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha CPSase_L_D2 PF02786.17 RKP03357.1 - 3.5e-72 242.3 0.0 5.1e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RKP03357.1 - 1.5e-46 157.5 0.7 9.9e-46 154.8 0.1 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RKP03357.1 - 3.3e-37 126.9 0.1 4.7e-36 123.2 0.0 2.7 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RKP03357.1 - 5.8e-17 61.3 0.1 1.7e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 RKP03357.1 - 2e-11 43.9 0.0 3.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 RKP03357.1 - 4.7e-09 35.9 0.1 6.4e-06 25.9 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 RKP03357.1 - 5.8e-05 23.7 0.1 0.38 11.5 0.0 3.3 3 0 0 3 3 2 2 HlyD family secretion protein PTS_EIIA_1 PF00358.20 RKP03357.1 - 0.0021 17.8 0.1 0.0075 16.0 0.0 1.9 1 1 1 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 RKP03357.1 - 0.0023 17.9 0.6 0.018 15.0 0.5 2.6 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain RimK PF08443.11 RKP03357.1 - 0.0023 17.5 0.0 0.0096 15.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 RKP03357.1 - 0.0026 17.0 0.1 0.074 12.3 0.0 2.6 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 RKP03357.1 - 0.0088 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 RKP03357.1 - 0.017 14.4 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 RKP03357.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 RKP03357.1 - 0.029 13.8 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PYNP_C PF07831.13 RKP03357.1 - 0.054 13.2 0.2 0.56 9.9 0.0 2.7 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.19 RKP03357.1 - 0.078 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DEAD_2 PF06733.15 RKP03358.1 - 4.5e-56 189.2 0.0 7.3e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 RKP03358.1 - 4.3e-46 157.0 4.4 3.5e-41 141.0 1.2 2.3 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 RKP03358.1 - 9.1e-44 149.6 0.0 3.6e-43 147.7 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 RKP03358.1 - 5.4e-05 23.3 0.0 0.0037 17.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 RKP03358.1 - 0.0032 16.3 0.0 0.02 13.7 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 RKP03358.1 - 0.0065 16.3 0.0 0.79 9.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 RKP03358.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain YtxC PF08812.11 RKP03358.1 - 0.16 11.5 0.3 0.68 9.5 0.1 2.0 2 0 0 2 2 2 0 YtxC-like family MDM10 PF12519.8 RKP03359.1 - 1.7e-37 129.4 0.0 8.5e-26 90.8 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial distribution and morphology protein 10 LETM1 PF07766.13 RKP03360.1 - 1.4e-100 336.1 1.5 2.8e-100 335.1 1.5 1.5 1 0 0 1 1 1 1 LETM1-like protein EF-hand_8 PF13833.6 RKP03360.1 - 1.4e-05 24.9 0.0 3.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 RKP03360.1 - 1.7e-05 25.2 0.0 5.7e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair SAP PF02037.27 RKP03360.1 - 0.0054 16.4 0.0 0.067 13.0 0.0 3.0 3 0 0 3 3 3 1 SAP domain EF-hand_6 PF13405.6 RKP03360.1 - 0.038 13.9 0.0 6.2 7.0 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain AnfO_nitrog PF09582.10 RKP03360.1 - 0.038 13.3 0.6 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) EF-hand_1 PF00036.32 RKP03360.1 - 0.054 13.1 0.0 2 8.1 0.0 2.9 2 0 0 2 2 2 0 EF hand DIT1_PvcA PF05141.12 RKP03361.1 - 1.5e-62 211.6 0.0 6.5e-62 209.5 0.0 1.8 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 RKP03361.1 - 3e-21 76.4 0.3 1.9e-19 70.5 0.3 2.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.32 RKP03362.1 - 1e-12 48.3 14.7 0.0006 20.6 0.5 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03362.1 - 7.1e-08 32.6 0.2 0.0067 16.7 0.0 4.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.23 RKP03363.1 - 7.4e-94 314.4 0.0 8.5e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP03363.1 - 1.7e-16 60.5 0.0 2.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 RKP03363.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Response_reg PF00072.24 RKP03364.1 - 3.4e-23 82.0 0.0 6.2e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 RKP03364.1 - 6.7e-22 78.1 0.1 1.4e-20 73.9 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 RKP03364.1 - 4.3e-17 62.7 0.0 3.6e-16 59.7 0.0 2.8 1 1 0 1 1 1 1 GAF domain HisKA PF00512.25 RKP03364.1 - 0.00024 21.1 0.5 0.0025 17.8 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 RKP03364.1 - 0.0014 19.3 0.0 0.0073 16.9 0.0 2.4 1 0 0 1 1 1 1 GAF domain Atg14 PF10186.9 RKP03364.1 - 0.98 8.4 4.1 1.8 7.6 4.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 RKP03364.1 - 6.6 7.4 11.7 4.8 7.8 7.0 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GSHPx PF00255.19 RKP03365.1 - 3.2e-35 120.0 0.1 4e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RKP03365.1 - 1.7e-08 34.4 0.1 3.2e-07 30.3 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKP03365.1 - 9.4e-06 25.4 0.1 5.1e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Redoxin NDUF_B8 PF05821.11 RKP03365.1 - 0.064 13.1 0.1 0.064 13.1 0.1 1.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DnaJ_C PF01556.18 RKP03366.1 - 5e-35 120.8 0.1 6.9e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKP03366.1 - 6.3e-24 83.9 4.3 9.5e-24 83.3 4.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4201 PF13870.6 RKP03367.1 - 1.8e-26 92.9 14.9 1.8e-26 92.9 14.9 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) TetR_C_19 PF17924.1 RKP03367.1 - 0.048 14.2 2.3 2.1 8.9 0.7 2.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FAM76 PF16046.5 RKP03367.1 - 9.3 5.5 17.0 17 4.7 17.0 1.6 1 1 0 1 1 1 0 FAM76 protein Dynein_light PF01221.18 RKP03368.1 - 2.4e-25 88.7 0.0 3e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 PCI PF01399.27 RKP03369.1 - 0.00017 22.1 0.0 0.0024 18.4 0.0 2.8 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 RKP03369.1 - 0.074 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix GPP34 PF05719.11 RKP03370.1 - 2.1e-61 207.5 1.0 2.7e-61 207.2 1.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Semialdhyde_dhC PF02774.18 RKP03371.1 - 3.4e-36 125.0 0.0 7e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 RKP03371.1 - 3.1e-29 101.9 0.1 4.7e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 RKP03371.1 - 0.0012 19.0 0.1 0.0021 18.2 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 RKP03371.1 - 0.071 13.8 0.0 0.35 11.6 0.0 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF4490 PF14892.6 RKP03372.1 - 1.9e-15 56.8 0.1 1.9e-15 56.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) zf-C2H2 PF00096.26 RKP03374.1 - 1e-12 47.7 19.5 5.5e-05 23.4 4.6 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKP03374.1 - 2.7e-12 46.5 11.8 1.9e-06 28.0 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKP03374.1 - 5e-10 39.3 17.1 0.00024 21.7 3.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKP03374.1 - 4.1e-05 23.3 11.5 0.0041 16.8 0.9 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type DZR PF12773.7 RKP03374.1 - 0.00036 20.5 0.6 0.00046 20.1 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-LITAF-like PF10601.9 RKP03374.1 - 0.00095 19.4 4.1 0.21 11.9 0.5 2.1 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain zf-C2H2_6 PF13912.6 RKP03374.1 - 0.001 19.0 11.0 0.15 12.1 1.3 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 RKP03374.1 - 0.0011 19.0 3.5 0.014 15.5 3.6 2.1 1 1 1 2 2 2 2 Zinc ribbon domain HalOD2 PF18547.1 RKP03374.1 - 0.0027 17.6 2.3 0.48 10.4 0.2 2.2 2 0 0 2 2 2 2 Halobacterial output domain 2 zinc_ribbon_4 PF13717.6 RKP03374.1 - 0.0028 17.5 2.0 1 9.3 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_9 PF14369.6 RKP03374.1 - 0.003 17.8 3.7 0.19 12.0 0.3 2.3 2 0 0 2 2 2 1 zinc-ribbon zf-trcl PF13451.6 RKP03374.1 - 0.0053 16.6 3.3 0.016 15.1 3.3 1.8 1 1 0 1 1 1 1 Probable zinc-ribbon domain HypA PF01155.19 RKP03374.1 - 0.0076 16.3 0.2 0.0085 16.1 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_3 PF13878.6 RKP03374.1 - 0.01 15.6 5.0 0.15 11.9 0.1 2.3 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_jaz PF12171.8 RKP03374.1 - 0.011 16.0 8.5 1.9 8.9 0.3 3.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-ISL3 PF14690.6 RKP03374.1 - 0.014 16.1 6.8 0.29 11.8 1.3 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_9 PF16293.5 RKP03374.1 - 0.016 15.1 2.1 7.2 6.5 0.1 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) TFIIS_C PF01096.18 RKP03374.1 - 0.019 14.8 2.3 0.72 9.8 0.3 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_2 PF12756.7 RKP03374.1 - 0.025 14.9 7.9 1.8 8.9 3.5 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 RKP03374.1 - 0.046 14.5 1.3 0.053 14.3 1.3 1.3 1 0 0 1 1 1 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 RKP03374.1 - 0.054 13.0 0.6 3.9 7.1 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding PADR1 PF08063.12 RKP03374.1 - 0.089 12.6 1.4 7.6 6.4 0.1 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain DUF2072 PF09845.9 RKP03374.1 - 0.09 13.0 5.7 0.54 10.5 0.8 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein zf-RING_7 PF02591.15 RKP03374.1 - 0.096 12.9 1.1 6.6 7.0 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-met PF12874.7 RKP03374.1 - 0.16 12.4 0.3 0.16 12.4 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-LYAR PF08790.11 RKP03374.1 - 0.16 11.9 5.5 1.9 8.5 0.4 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Elf1 PF05129.13 RKP03374.1 - 0.25 11.4 0.4 0.25 11.4 0.4 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.19 RKP03374.1 - 0.3 11.2 3.9 7.4 6.7 3.7 2.1 1 1 0 1 1 1 0 Ribosomal L37ae protein family Pox_A3L PF05288.11 RKP03374.1 - 0.52 10.3 4.8 5.4 7.1 0.4 2.2 1 1 1 2 2 2 0 Poxvirus A3L Protein Zn_ribbon_SprT PF17283.2 RKP03374.1 - 0.64 10.0 7.4 2.4 8.1 7.3 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain OrfB_Zn_ribbon PF07282.11 RKP03374.1 - 0.79 9.7 4.9 12 5.9 0.6 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 RKP03374.1 - 1.4 8.7 8.0 2.3 8.0 1.0 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF983 PF06170.12 RKP03374.1 - 1.5 9.2 2.9 28 5.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zinc_ribbon_5 PF13719.6 RKP03374.1 - 2.4 8.0 5.3 12 5.7 0.4 2.7 2 1 1 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 RKP03374.1 - 2.5 8.2 8.0 6.9 6.7 1.5 2.2 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 RKP03374.1 - 2.7 8.5 11.6 5.8 7.4 4.6 2.9 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger MARVEL PF01284.23 RKP03375.1 - 0.0033 17.5 3.5 0.0051 16.8 3.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain Bac_rhodopsin PF01036.18 RKP03375.1 - 0.66 9.5 6.1 0.99 8.9 6.1 1.2 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein RabGAP-TBC PF00566.18 RKP03376.1 - 1.3e-32 113.2 3.1 8.3e-30 104.0 0.0 2.8 2 1 0 2 2 2 2 Rab-GTPase-TBC domain IMPDH PF00478.25 RKP03377.1 - 2.9e-131 437.6 1.8 3.5e-131 437.3 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 RKP03377.1 - 1e-12 48.1 0.7 1.5e-08 34.4 1.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase CBS PF00571.28 RKP03377.1 - 1e-12 48.3 0.2 1.8e-07 31.5 0.1 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 RKP03377.1 - 1.5e-08 34.0 3.3 2.9e-08 33.1 3.3 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 RKP03377.1 - 2.7e-05 23.7 1.7 8.9e-05 22.1 1.7 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 RKP03377.1 - 3.6e-05 23.2 1.2 9.3e-05 21.8 0.6 1.9 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 RKP03377.1 - 0.0035 16.6 0.2 0.0097 15.1 0.2 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF561 PF04481.12 RKP03377.1 - 0.027 13.7 2.3 0.16 11.1 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF561) Dus PF01207.17 RKP03377.1 - 0.058 12.5 0.1 0.099 11.7 0.1 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) IGPS PF00218.21 RKP03377.1 - 0.13 11.4 0.1 7.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 RKP03377.1 - 0.15 11.4 0.6 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 RKP03377.1 - 0.62 9.2 3.1 0.34 10.1 0.6 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase GRIM-19 PF06212.12 RKP03378.1 - 1.4e-27 96.2 0.1 5e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 GRIM-19 protein VWA_2 PF13519.6 RKP03379.1 - 1.7e-06 28.6 0.0 4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PI31_Prot_C PF08577.11 RKP03380.1 - 2.5e-12 47.8 10.3 2.5e-12 47.8 10.3 4.0 2 2 2 4 4 4 1 PI31 proteasome regulator PI31_Prot_N PF11566.8 RKP03380.1 - 2.3e-08 34.0 0.0 5.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal Glyco_tran_28_C PF04101.16 RKP03381.1 - 5.4e-23 81.8 0.0 7.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Amdase PF17645.1 RKP03381.1 - 0.016 14.8 0.5 0.022 14.4 0.5 1.3 1 0 0 1 1 1 0 Arylmalonate decarboxylase Glyco_trans_1_3 PF13528.6 RKP03381.1 - 0.045 13.0 0.1 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 UDPGT PF00201.18 RKP03381.1 - 0.12 11.1 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase TPR_12 PF13424.6 RKP03382.1 - 0.0091 16.3 2.7 10 6.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat FliJ PF02050.16 RKP03382.1 - 0.012 15.9 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein TPR_7 PF13176.6 RKP03382.1 - 0.049 13.7 0.5 23 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP03382.1 - 0.21 11.5 2.3 1 9.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03382.1 - 2.2 8.9 9.7 2.6 8.6 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat PGP_phosphatase PF09419.10 RKP03383.1 - 8.6e-37 126.3 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 RKP03383.1 - 2.3e-07 30.8 0.1 4.8e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Glyco_transf_5 PF08323.11 RKP03383.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain HAD_2 PF13419.6 RKP03383.1 - 0.095 12.8 0.2 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKP03383.1 - 0.17 12.1 0.0 0.57 10.4 0.0 1.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L19 PF01245.20 RKP03384.1 - 6.8e-09 35.6 0.0 9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Epimerase PF01370.21 RKP03385.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RKP03385.1 - 1.4e-13 50.6 0.1 2.3e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 RKP03385.1 - 1.7e-11 43.7 0.0 5.3e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 RKP03385.1 - 7e-09 35.5 0.0 2.2e-08 33.9 0.0 1.7 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 RKP03385.1 - 1.2e-07 31.9 0.0 2.9e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 RKP03385.1 - 3.5e-05 23.1 1.0 0.0031 16.7 1.0 2.9 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 RKP03385.1 - 0.017 15.4 0.0 0.061 13.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4394 PF14339.6 RKP03385.1 - 0.094 12.1 0.0 0.21 10.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) eIF-3c_N PF05470.12 RKP03386.1 - 3.2e-146 488.1 0.7 4.1e-146 487.7 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 RKP03386.1 - 7.8e-12 45.6 0.2 8e-10 39.2 0.0 2.9 2 0 0 2 2 2 1 PCI domain T3SS_needle_E PF08988.10 RKP03386.1 - 0.076 13.2 0.7 15 5.9 0.0 3.7 4 0 0 4 4 4 0 Type III secretion system, cytoplasmic E component of needle Sigma70_ner PF04546.13 RKP03386.1 - 0.15 11.9 6.6 1.8 8.4 0.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3402 PF11882.8 RKP03386.1 - 0.58 9.2 3.3 0.65 9.0 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Peptidase_M28 PF04389.17 RKP03387.1 - 3.7e-29 101.8 0.0 5.4e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 RKP03387.1 - 2e-08 34.2 0.0 1.1e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Aa_trans PF01490.18 RKP03388.1 - 0.013 14.2 10.2 0.038 12.7 1.5 2.2 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein Pkinase PF00069.25 RKP03389.1 - 3.9e-17 62.5 0.0 1.2e-06 28.1 0.0 3.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03389.1 - 8e-06 25.3 0.0 0.0024 17.2 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Synaptobrevin PF00957.21 RKP03391.1 - 3.4e-13 49.2 0.2 6.4e-13 48.3 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 RKP03391.1 - 7.7e-13 48.3 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Autophagy_N PF03986.13 RKP03391.1 - 0.099 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RAMP4 PF06624.12 RKP03392.1 - 3.6e-06 26.9 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Complex1_LYR PF05347.15 RKP03394.1 - 1.9e-11 43.8 1.2 3.4e-11 43.0 1.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Med1 PF10744.9 RKP03394.1 - 7.4e-07 28.6 0.0 6.3e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Complex1_LYR_2 PF13233.6 RKP03394.1 - 0.0053 17.5 0.9 0.011 16.4 0.9 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF2742 PF10888.8 RKP03394.1 - 0.18 12.1 5.6 0.053 13.8 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) SMC_N PF02463.19 RKP03395.1 - 3e-19 69.4 0.0 1.4e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RKP03395.1 - 4.8e-19 69.6 0.0 1.1e-17 65.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 RKP03395.1 - 9.2e-07 28.9 0.0 2.2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RKP03395.1 - 3.2e-05 23.6 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 RKP03395.1 - 0.00024 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 RKP03395.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 4.8 6 2 2 9 9 9 2 AAA domain ABC_tran PF00005.27 RKP03395.1 - 0.0049 17.4 3.0 0.042 14.4 0.0 3.4 2 1 0 3 3 3 1 ABC transporter DUF1843 PF08898.10 RKP03395.1 - 0.018 15.5 2.3 0.068 13.7 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) AAA PF00004.29 RKP03395.1 - 0.15 12.5 4.3 0.48 10.8 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKP03395.1 - 0.15 12.0 2.5 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Transglut_core PF01841.19 RKP03395.1 - 0.19 12.2 3.7 0.57 10.7 0.1 3.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily Bcr-Abl_Oligo PF09036.10 RKP03395.1 - 0.73 9.9 3.6 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain AAA_22 PF13401.6 RKP03395.1 - 0.75 10.1 4.9 3 8.1 0.3 3.9 3 1 0 3 3 3 0 AAA domain zf-C4H2 PF10146.9 RKP03396.1 - 2e-09 38.1 0.0 2.6e-09 37.7 0.0 1.2 1 1 0 1 1 1 1 Zinc finger-containing protein APH PF01636.23 RKP03396.1 - 2.8 7.8 12.0 0.74 9.7 9.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family HSCB_C PF07743.13 RKP03396.1 - 4 8.0 6.6 4.1 8.0 1.9 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain BolA PF01722.18 RKP03397.1 - 1.7e-28 98.7 0.1 2.1e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein U1snRNP70_N PF12220.8 RKP03398.1 - 1.1e-18 67.6 0.0 3.8e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 RKP03398.1 - 1.1e-13 50.8 0.0 3.1e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03398.1 - 0.21 11.8 0.0 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif Spc7 PF08317.11 RKP03399.1 - 9.2e-30 103.6 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4407 PF14362.6 RKP03399.1 - 0.04 13.3 12.2 0.08 12.3 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Treacle PF03546.14 RKP03401.1 - 0.0039 16.1 3.1 0.0054 15.6 3.1 1.1 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle Pro_isomerase PF00160.21 RKP03402.1 - 1.3e-44 152.3 0.0 1.4e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transp_inhibit PF18791.1 RKP03403.1 - 0.41 10.2 2.1 0.9 9.1 2.1 1.5 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Helicase_C PF00271.31 RKP03404.1 - 4.2e-17 62.5 0.0 1.7e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKP03404.1 - 1.3e-14 54.4 0.0 2.3e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 RKP03404.1 - 1.1e-07 32.5 0.3 4.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 RecQ zinc-binding AAA PF00004.29 RKP03405.1 - 3.8e-63 211.8 0.0 2.1e-43 147.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKP03405.1 - 3.3e-14 52.4 10.3 3.5e-11 42.7 0.4 3.1 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 RKP03405.1 - 1.8e-08 34.3 0.0 0.00014 21.7 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RKP03405.1 - 1.8e-08 34.9 9.8 0.0014 19.1 0.0 4.5 2 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 RKP03405.1 - 5e-08 33.0 0.0 0.00062 19.8 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RKP03405.1 - 2.2e-07 31.1 0.0 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RKP03405.1 - 1e-05 25.7 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RKP03405.1 - 1.1e-05 25.8 0.0 0.14 12.4 0.0 3.4 2 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 RKP03405.1 - 5.1e-05 23.6 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 RKP03405.1 - 0.0001 22.1 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 RKP03405.1 - 0.00019 21.4 0.1 0.59 10.0 0.0 3.7 3 1 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 RKP03405.1 - 0.0004 19.8 0.2 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RKP03405.1 - 0.00049 19.4 0.0 0.0067 15.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 RKP03405.1 - 0.0022 17.6 0.9 2.8 7.5 0.1 3.3 3 1 1 4 4 4 2 AAA domain AAA_7 PF12775.7 RKP03405.1 - 0.0028 17.2 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 RKP03405.1 - 0.0031 17.4 0.0 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 RKP03405.1 - 0.0067 16.4 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RKP03405.1 - 0.0081 16.4 0.0 0.77 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 RKP03405.1 - 0.0098 15.6 0.0 1.3 8.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 RKP03405.1 - 0.018 15.1 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKP03405.1 - 0.02 14.6 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 RKP03405.1 - 0.029 14.5 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 RKP03405.1 - 0.032 13.1 0.0 0.5 9.2 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_3 PF07726.11 RKP03405.1 - 0.082 12.8 0.0 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hpr_kinase_C PF07475.12 RKP03405.1 - 0.13 11.8 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 RKP03405.1 - 0.15 12.6 0.0 31 5.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.9 RKP03405.1 - 0.17 11.0 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 BRO1 PF03097.18 RKP03406.1 - 5.8e-96 321.6 0.0 1.4e-94 317.1 0.0 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 RKP03406.1 - 9.3e-67 225.4 11.1 1.4e-66 224.8 11.1 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV TPR_1 PF00515.28 RKP03406.1 - 0.1 12.4 1.6 2.9 7.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD-SLDH PF12318.8 RKP03406.1 - 6 6.9 10.1 1.2 9.2 1.5 3.6 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase MoCF_biosynth PF00994.24 RKP03407.1 - 5e-18 65.1 0.0 8.2e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain MCM2_N PF12619.8 RKP03408.1 - 0.0085 16.4 3.4 0.013 15.8 3.4 1.2 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 EIF_2_alpha PF07541.12 RKP03409.1 - 1.1e-38 131.9 0.1 2.9e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 RKP03409.1 - 3.6e-14 52.8 0.6 7.4e-14 51.8 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 RKP03409.1 - 0.0033 16.8 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Helicase_C PF00271.31 RKP03410.1 - 2.4e-12 47.2 0.0 4.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKP03410.1 - 0.016 15.0 0.0 0.072 12.8 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 RKP03410.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 RKP03410.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TK PF00265.18 RKP03410.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Response_reg PF00072.24 RKP03411.1 - 1.9e-21 76.3 0.2 4.3e-21 75.2 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain NYD-SP28_assoc PF14775.6 RKP03412.1 - 1.3e-17 63.7 1.7 1.3e-17 63.7 1.7 4.6 4 1 1 5 5 5 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 RKP03412.1 - 1.7e-17 63.3 12.5 1.7e-17 63.3 12.5 5.9 3 1 4 7 7 7 2 Sperm tail Glyco_hydr_30_2 PF14587.6 RKP03413.1 - 1e-23 84.6 3.1 3.5e-20 72.9 1.7 2.3 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 RKP03413.1 - 0.0045 17.2 0.4 0.011 16.0 0.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain AAA PF00004.29 RKP03414.1 - 1.2e-41 142.2 0.0 2.4e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RKP03414.1 - 1.8e-18 66.3 0.1 3.4e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RKP03414.1 - 1.1e-08 34.7 0.3 2.6e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKP03414.1 - 1.1e-05 25.4 0.1 8.7e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RKP03414.1 - 5e-05 23.5 0.8 0.00017 21.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RKP03414.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RKP03414.1 - 0.0001 22.7 0.4 0.015 15.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKP03414.1 - 0.00035 20.8 0.9 0.091 13.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 RKP03414.1 - 0.0027 17.2 0.0 0.035 13.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 RKP03414.1 - 0.014 15.2 0.3 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RKP03414.1 - 0.018 14.4 0.1 0.044 13.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKP03414.1 - 0.019 15.1 0.0 0.064 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain JIP_LZII PF16471.5 RKP03414.1 - 0.019 15.1 3.7 0.067 13.4 3.7 1.9 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II IstB_IS21 PF01695.17 RKP03414.1 - 0.026 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 RKP03414.1 - 0.037 13.2 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 RKP03414.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RKP03414.1 - 0.051 13.3 0.1 0.2 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKP03414.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Tocopherol_cycl PF14249.6 RKP03415.1 - 1.8e-12 47.1 0.0 0.0028 16.8 0.0 3.7 3 1 0 3 3 3 3 Tocopherol cyclase KIAA1430 PF13879.6 RKP03416.1 - 2.7e-09 37.7 1.8 9.4e-05 23.1 0.0 3.0 1 1 2 3 3 3 3 KIAA1430 homologue ASD2 PF08687.11 RKP03416.1 - 0.0082 15.7 1.6 0.013 15.0 1.6 1.3 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Prenyltrans PF00432.21 RKP03417.1 - 3.4e-49 164.3 12.5 6.4e-11 41.8 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 RKP03417.1 - 0.11 11.6 0.0 16 4.5 0.0 3.4 2 2 1 4 4 4 0 Squalene-hopene cyclase N-terminal domain MARVEL PF01284.23 RKP03418.1 - 4.2e-07 30.1 8.7 0.00033 20.7 3.7 2.3 2 0 0 2 2 2 2 Membrane-associating domain zf-C2H2 PF00096.26 RKP03419.1 - 2.3e-13 49.8 18.7 0.00027 21.2 5.7 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP03419.1 - 3.1e-08 33.8 17.6 0.014 16.2 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP03419.1 - 2.3e-05 24.6 6.7 0.0024 18.2 0.9 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf_UBZ PF18439.1 RKP03419.1 - 0.0021 17.6 2.7 0.33 10.6 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 RKP03419.1 - 0.0044 16.6 3.3 0.14 11.8 0.6 2.4 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain TFIIS_C PF01096.18 RKP03419.1 - 0.014 15.2 3.2 1.6 8.6 0.7 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-met PF12874.7 RKP03419.1 - 0.019 15.3 2.1 0.52 10.8 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RKP03419.1 - 0.039 13.7 4.8 0.039 13.7 4.8 3.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.6 RKP03419.1 - 0.059 13.3 6.0 0.43 10.5 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 RKP03419.1 - 0.071 13.1 0.6 0.079 13.0 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 RKP03419.1 - 0.076 12.9 3.0 4.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain CpXC PF14353.6 RKP03419.1 - 0.12 12.5 2.0 6.2 6.9 0.2 2.3 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_13 PF09855.9 RKP03419.1 - 0.15 12.3 1.9 13 6.1 0.5 2.4 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.10 RKP03419.1 - 0.15 12.2 4.7 4.6 7.4 3.8 2.7 1 1 1 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 RKP03419.1 - 0.16 12.0 0.5 0.16 12.0 0.5 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.8 RKP03419.1 - 0.3 11.4 6.1 7.1 7.0 0.8 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP03419.1 - 0.32 11.0 8.7 5.4 7.1 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 RKP03419.1 - 0.49 10.3 9.9 4.6 7.2 2.2 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 RKP03419.1 - 0.58 10.3 6.4 1.8 8.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) NAD_binding_2 PF03446.15 RKP03420.1 - 3.2e-38 131.4 0.7 5.3e-38 130.7 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 RKP03420.1 - 1.3e-29 102.9 0.0 2.9e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 RKP03420.1 - 0.0071 16.6 0.3 0.38 11.0 0.3 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 RKP03420.1 - 0.043 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RKP03420.1 - 0.064 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TRAM_LAG1_CLN8 PF03798.16 RKP03421.1 - 1.2e-35 123.1 15.0 1.3e-35 122.9 15.0 1.0 1 0 0 1 1 1 1 TLC domain B9-C2 PF07162.11 RKP03422.1 - 2.7e-29 102.5 0.1 1.5e-16 61.1 0.1 2.0 1 1 1 2 2 2 2 Ciliary basal body-associated, B9 protein Acetyltransf_17 PF17668.1 RKP03422.1 - 0.037 14.8 0.0 0.047 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.20 RKP03423.1 - 2.2e-151 505.1 0.8 3.4e-151 504.4 0.0 1.7 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 RKP03423.1 - 1.7e-06 27.1 0.0 2e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Med18 PF09637.10 RKP03424.1 - 2.3e-17 63.7 0.0 8e-14 52.1 0.0 2.6 1 1 1 2 2 2 2 Med18 protein Arrestin_N PF00339.29 RKP03425.1 - 2.1e-11 44.1 0.0 4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RKP03425.1 - 0.0028 18.1 0.0 0.026 15.0 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RKP03425.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Rgp1 CRM1_C PF08767.11 RKP03426.1 - 5.5e-129 429.9 10.5 5.6e-129 429.9 1.4 3.1 3 0 0 3 3 3 2 CRM1 C terminal Xpo1 PF08389.12 RKP03426.1 - 1.8e-41 141.6 5.6 1.8e-41 141.6 5.6 3.9 5 1 1 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 RKP03426.1 - 8.9e-29 98.9 2.6 2.6e-28 97.4 2.6 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 RKP03426.1 - 7.9e-27 93.1 1.8 7.9e-27 93.1 1.8 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 RKP03426.1 - 5.5e-19 67.4 0.9 1.3e-18 66.1 0.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 RKP03426.1 - 3e-13 49.5 0.2 1e-12 47.8 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain MMS19_C PF12460.8 RKP03426.1 - 0.0062 15.7 6.1 0.28 10.3 0.1 3.8 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 RKP03426.1 - 0.043 13.7 6.9 4.5 7.2 0.0 4.4 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) PEX11 PF05648.14 RKP03426.1 - 0.12 11.8 0.2 0.23 10.9 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) UCH PF00443.29 RKP03426.1 - 0.24 10.9 0.4 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Prolamin_like PF05617.11 RKP03426.1 - 0.55 10.4 2.2 20 5.5 0.1 3.4 3 0 0 3 3 3 0 Prolamin-like ATP-synt PF00231.19 RKP03427.1 - 2.9e-72 243.7 11.9 3.3e-72 243.6 11.9 1.0 1 0 0 1 1 1 1 ATP synthase INCENP_ARK-bind PF03941.15 RKP03427.1 - 0.0028 17.5 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Cactin_mid PF10312.9 RKP03427.1 - 0.0067 16.2 1.4 0.0075 16.0 0.2 1.7 2 0 0 2 2 2 1 Conserved mid region of cactin TPR_2 PF07719.17 RKP03429.1 - 1.2e-38 128.1 18.8 5.7e-05 22.9 0.5 11.7 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03429.1 - 2.4e-34 115.7 22.9 4.2e-07 29.5 1.3 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03429.1 - 3.3e-23 79.9 11.7 0.011 15.9 0.2 11.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03429.1 - 5.3e-23 81.3 26.0 0.00019 21.9 5.0 7.8 6 2 2 9 9 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 RKP03429.1 - 1.6e-20 73.5 30.5 4.9e-08 33.5 0.9 7.9 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03429.1 - 1.1e-18 66.6 23.6 4.2e-06 26.3 2.4 8.6 6 2 3 9 9 8 4 TPR repeat TPR_12 PF13424.6 RKP03429.1 - 5.5e-18 65.0 38.9 1.3e-06 28.6 1.8 9.5 5 4 5 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 RKP03429.1 - 2e-17 62.4 29.5 0.26 12.2 0.1 11.7 7 2 4 12 12 11 6 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03429.1 - 1.1e-13 50.8 27.9 0.034 14.8 0.1 11.8 12 0 0 12 12 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP03429.1 - 1.1e-13 51.2 23.9 2.2e-06 27.8 5.4 6.4 5 4 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RKP03429.1 - 2.3e-12 46.0 31.8 0.0095 15.9 0.1 11.0 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03429.1 - 3e-08 33.5 24.2 0.0051 17.1 0.0 7.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 RKP03429.1 - 1.8e-06 27.6 24.3 0.18 11.7 0.0 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat BTAD PF03704.17 RKP03429.1 - 2.1e-06 28.2 11.3 0.039 14.4 0.5 5.0 3 1 1 4 4 4 2 Bacterial transcriptional activator domain TPR_9 PF13371.6 RKP03429.1 - 3.5e-05 23.8 10.0 0.17 12.0 0.8 6.0 2 2 5 7 7 7 2 Tetratricopeptide repeat DUF2225 PF09986.9 RKP03429.1 - 0.00019 21.3 1.6 0.58 9.8 0.2 3.5 2 2 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 RKP03429.1 - 0.00045 20.0 22.2 1.4 8.6 0.1 7.3 4 3 1 6 6 6 2 26S proteasome subunit RPN7 Coatomer_E PF04733.14 RKP03429.1 - 0.005 16.3 0.9 0.022 14.2 0.1 2.5 2 1 0 2 2 2 1 Coatomer epsilon subunit DUF4810 PF16068.5 RKP03429.1 - 0.0067 16.9 1.8 13 6.4 0.0 5.5 6 1 1 7 7 5 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 RKP03429.1 - 0.013 15.8 13.3 0.025 14.9 0.7 5.2 2 2 3 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RKP03429.1 - 0.021 14.3 0.0 6.3 6.3 0.0 3.5 4 0 0 4 4 4 0 SHNi-TPR NARP1 PF12569.8 RKP03429.1 - 0.038 12.9 9.8 0.38 9.6 0.0 3.7 3 1 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 RKP03429.1 - 0.56 11.0 12.4 13 6.7 0.1 7.5 11 0 0 11 11 5 0 Tetratricopeptide repeat MIT PF04212.18 RKP03429.1 - 1.3 9.2 23.5 33 4.6 0.1 7.7 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 RKP03429.1 - 2.1 9.1 8.4 16 6.4 0.1 5.5 6 0 0 6 6 5 0 Sel1 repeat TPR_1 PF00515.28 RKP03430.1 - 1.8e-14 52.8 5.4 3.2e-07 29.9 0.5 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03430.1 - 2.2e-12 46.1 4.1 1.6e-06 27.8 0.2 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03430.1 - 4.3e-10 39.1 6.7 1e-09 37.9 2.7 2.2 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 RKP03430.1 - 3.7e-07 30.4 0.6 0.00039 21.0 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03430.1 - 1.3e-06 28.1 2.6 0.024 14.8 0.4 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKP03430.1 - 1.5e-06 28.8 2.7 2.4e-06 28.1 2.7 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03430.1 - 8.8e-06 25.8 6.3 0.00029 21.0 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03430.1 - 4.3e-05 23.7 2.4 0.00016 21.9 2.4 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKP03430.1 - 0.00023 21.0 1.0 0.13 12.3 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03430.1 - 0.00069 20.1 2.3 0.0016 18.9 2.3 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKP03430.1 - 0.0073 15.6 0.1 0.0075 15.5 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 RKP03430.1 - 0.011 15.6 4.3 0.18 11.7 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat L31 PF09784.9 RKP03431.1 - 6.9e-15 55.3 0.4 8.1e-15 55.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Chorismate_synt PF01264.21 RKP03432.1 - 4.2e-135 449.7 0.0 4.8e-135 449.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase RRM_1 PF00076.22 RKP03433.1 - 1e-21 76.5 0.0 1.2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LsmAD PF06741.13 RKP03434.1 - 1.5e-24 86.3 4.3 3.4e-24 85.2 4.3 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 RKP03434.1 - 2.9e-19 69.0 0.0 5.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Carn_acyltransf PF00755.20 RKP03435.1 - 5.3e-165 550.4 0.0 5.9e-165 550.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CRAL_TRIO PF00650.20 RKP03436.1 - 6.1e-38 130.0 0.0 1.1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 RKP03436.1 - 2.5e-10 40.4 0.0 4.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 RKP03436.1 - 7.2e-07 29.5 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-NOSIP PF15906.5 RKP03436.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_1 PF00515.28 RKP03437.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKP03437.1 - 0.0045 17.1 7.0 0.0045 17.1 7.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03437.1 - 0.0077 16.4 1.8 0.05 13.8 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03437.1 - 0.011 16.1 0.2 0.011 16.1 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP03437.1 - 0.021 14.7 0.9 0.021 14.7 0.9 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03437.1 - 0.037 14.3 4.9 0.037 14.3 4.9 2.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03437.1 - 0.044 13.9 0.6 0.044 13.9 0.6 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03437.1 - 0.06 13.0 7.1 0.23 11.2 2.5 2.9 2 1 1 3 3 3 0 TPR repeat NARP1 PF12569.8 RKP03437.1 - 0.17 10.8 0.9 0.39 9.6 0.4 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Hexokinase_2 PF03727.16 RKP03438.1 - 2.9e-83 279.0 0.0 3.8e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RKP03438.1 - 8.4e-67 224.9 0.1 1.8e-66 223.9 0.0 1.5 2 0 0 2 2 2 1 Hexokinase ArfGap PF01412.18 RKP03439.1 - 2e-32 111.7 0.1 6.6e-32 110.0 0.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RKP03439.1 - 3.7e-16 59.6 12.1 6.1e-16 58.8 12.1 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 RKP03439.1 - 1e-07 32.4 0.0 2.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Y_phosphatase2 PF03162.13 RKP03440.1 - 7.8e-55 184.9 0.0 8.9e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKP03440.1 - 0.00024 21.1 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKP03440.1 - 0.036 13.6 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MT PF12777.7 RKP03442.1 - 2.2e-160 533.4 14.1 2.6e-160 533.1 12.1 2.2 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 RKP03442.1 - 3.2e-160 534.5 0.9 9.9e-158 526.3 0.1 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RKP03442.1 - 6.5e-155 515.0 0.4 3.2e-152 506.2 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKP03442.1 - 2.3e-123 412.2 3.3 2.3e-123 412.2 3.3 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKP03442.1 - 2.8e-98 329.0 1.7 5.1e-98 328.1 0.1 2.5 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKP03442.1 - 1.5e-97 326.0 0.1 2.6e-96 321.9 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKP03442.1 - 2e-83 278.8 0.7 2e-83 278.8 0.7 2.1 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKP03442.1 - 2.3e-73 245.6 0.1 2.9e-66 222.4 0.0 3.9 4 0 0 4 4 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKP03442.1 - 1.1e-51 174.9 0.0 1.3e-49 168.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKP03442.1 - 1.1e-37 128.7 0.0 3.5e-36 123.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RKP03442.1 - 1.7e-36 124.4 0.3 9.1e-36 122.1 0.3 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKP03442.1 - 9.1e-26 90.5 0.0 7e-14 52.0 0.0 6.3 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKP03442.1 - 1.7e-21 76.7 0.1 5.3e-21 75.1 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RKP03442.1 - 1.3e-10 41.9 2.4 0.0048 17.3 0.0 6.3 6 1 1 7 7 5 2 AAA ATPase domain AAA_22 PF13401.6 RKP03442.1 - 1.3e-07 32.0 0.0 0.36 11.1 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 RKP03442.1 - 3.7e-06 27.4 0.2 0.028 14.8 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RKP03442.1 - 5.6e-06 26.2 0.0 4.5 6.9 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 RKP03442.1 - 0.0006 20.4 0.9 0.48 11.0 0.0 4.3 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 RKP03442.1 - 0.00089 19.0 0.0 2.2 7.9 0.0 3.9 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_19 PF13245.6 RKP03442.1 - 0.0011 19.3 4.2 3.9 7.8 0.0 4.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 RKP03442.1 - 0.0021 18.4 0.1 17 5.8 0.1 3.9 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 RKP03442.1 - 0.0029 18.1 1.0 2.3 8.7 0.0 4.3 4 0 0 4 4 3 1 ABC transporter Sigma54_activ_2 PF14532.6 RKP03442.1 - 0.0031 17.6 0.1 4.2 7.5 0.0 3.6 3 0 0 3 3 2 1 Sigma-54 interaction domain NACHT PF05729.12 RKP03442.1 - 0.0073 16.2 0.1 0.94 9.4 0.0 3.5 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 RKP03442.1 - 0.011 15.8 0.9 7.5 6.6 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 RKP03442.1 - 0.027 13.7 0.0 0.61 9.2 0.0 2.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_29 PF13555.6 RKP03442.1 - 0.031 14.0 0.3 15 5.4 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 RKP03442.1 - 0.033 14.3 0.2 61 3.8 0.0 4.3 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 RKP03442.1 - 0.04 13.9 0.5 2.9 7.8 0.0 3.8 4 0 0 4 4 3 0 Rad17 P-loop domain Mg_chelatase PF01078.21 RKP03442.1 - 0.048 13.0 0.1 13 5.1 0.0 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RKP03442.1 - 0.068 12.3 0.0 33 3.5 0.0 3.8 4 0 0 4 4 3 0 Protein of unknown function (DUF815) CbiA PF01656.23 RKP03442.1 - 0.16 12.0 0.0 8.6 6.4 0.0 3.3 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RTA1 PF04479.13 RKP03442.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RTA1 like protein IFT46_B_C PF12317.8 RKP03442.1 - 1.1 8.9 7.6 2.9 7.6 1.9 2.8 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal GreA_GreB_N PF03449.15 RKP03442.1 - 3.3 7.9 7.1 0.53 10.5 0.7 3.2 2 0 0 2 2 1 0 Transcription elongation factor, N-terminal Ax_dynein_light PF10211.9 RKP03443.1 - 7.2e-80 267.4 13.9 8.3e-80 267.2 13.9 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Collectrin PF16959.5 RKP03443.1 - 0.011 15.5 0.2 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 Renal amino acid transporter YlbD_coat PF14071.6 RKP03443.1 - 0.32 11.3 2.9 1.4 9.2 0.4 2.2 2 0 0 2 2 2 0 Putative coat protein PRKG1_interact PF15898.5 RKP03443.1 - 0.82 10.6 9.7 0.35 11.8 6.1 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 RKP03443.1 - 1.6 9.0 5.5 1.1 9.5 3.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2570 PF10828.8 RKP03443.1 - 1.9 8.4 8.3 0.23 11.3 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) MORN PF02493.20 RKP03444.1 - 1.3e-36 122.3 24.4 9.4e-09 34.7 2.5 6.4 6 0 0 6 6 6 6 MORN repeat Rib PF08428.10 RKP03444.1 - 0.035 14.1 0.1 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Rib/alpha-like repeat RhoGEF PF00621.20 RKP03445.1 - 2e-29 103.1 3.1 4.4e-29 102.0 3.1 1.6 1 0 0 1 1 1 1 RhoGEF domain RA PF00788.23 RKP03445.1 - 3.7e-07 30.7 0.1 7.9e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain HR1 PF02185.16 RKP03445.1 - 6.2e-07 29.4 5.3 3e-06 27.3 2.5 2.8 2 0 0 2 2 2 1 Hr1 repeat C1_1 PF00130.22 RKP03445.1 - 0.0013 18.5 9.4 0.0025 17.7 9.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 RKP03445.1 - 0.0038 17.7 0.0 0.019 15.5 0.0 2.2 1 0 0 1 1 1 1 PH domain JAKMIP_CC3 PF16034.5 RKP03445.1 - 0.036 14.0 0.2 0.24 11.3 0.2 2.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Uds1 PF15456.6 RKP03445.1 - 0.24 11.6 6.4 0.13 12.4 2.5 2.5 2 0 0 2 2 2 0 Up-regulated During Septation CpxA_peri PF16527.5 RKP03445.1 - 9.4 6.6 5.7 7.5 6.9 0.6 2.9 3 0 0 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain Yae1_N PF09811.9 RKP03446.1 - 1.7e-09 37.2 0.8 2.3e-09 36.8 0.8 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ribosomal_S11 PF00411.19 RKP03447.1 - 2.3e-47 160.0 1.3 2.8e-47 159.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 RKP03447.1 - 0.022 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 RKP03447.1 - 0.032 13.5 0.1 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme OTU PF02338.19 RKP03449.1 - 4.3e-05 24.0 0.0 7.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-H2C2_2 PF13465.6 RKP03450.1 - 5.8e-11 42.3 14.6 1.2e-05 25.5 2.9 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKP03450.1 - 8.5e-11 41.7 19.9 0.00043 20.6 4.8 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP03450.1 - 5.4e-08 33.0 19.4 0.0011 19.6 4.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-LYAR PF08790.11 RKP03450.1 - 0.0069 16.3 6.0 0.015 15.2 0.2 2.9 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 RKP03450.1 - 0.017 15.6 7.9 0.72 10.3 0.7 2.9 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 RKP03450.1 - 0.034 14.4 4.6 0.39 11.0 4.6 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_6 PF13912.6 RKP03450.1 - 0.052 13.6 12.2 0.11 12.6 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKP03450.1 - 0.067 13.5 2.0 0.39 11.1 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RKP03450.1 - 0.11 12.1 1.9 13 5.5 0.8 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 RKP03450.1 - 0.13 12.9 1.4 2.6 8.8 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-H2C2_5 PF13909.6 RKP03450.1 - 0.38 10.6 14.7 4.5 7.1 6.8 3.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 RKP03450.1 - 0.88 9.9 9.3 0.074 13.4 2.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 RKP03450.1 - 1.4 9.0 11.7 0.73 9.9 9.4 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf_C2H2_ZHX PF18387.1 RKP03450.1 - 2.3 7.9 7.4 4.3 7.1 2.9 2.5 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 RKP03450.1 - 3.4 8.0 13.9 1.2 9.5 0.5 3.2 3 0 0 3 3 3 0 zinc-ribbon PigN PF04987.14 RKP03451.1 - 2.3e-115 386.1 24.9 3e-115 385.7 24.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RKP03451.1 - 1.3e-13 51.3 2.0 9.4e-13 48.5 2.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RKP03451.1 - 1.9e-06 27.5 0.2 4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RKP03451.1 - 0.00022 20.7 0.1 0.00038 19.9 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily THOC7 PF05615.13 RKP03452.1 - 8.9e-14 51.9 9.3 8.9e-14 51.9 9.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 TAP42 PF04177.12 RKP03452.1 - 0.03 13.5 10.0 0.04 13.1 10.0 1.2 1 0 0 1 1 1 0 TAP42-like family DUF3037 PF11236.8 RKP03452.1 - 0.33 11.4 5.8 0.18 12.2 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DMAP_binding PF06464.11 RKP03452.1 - 1.1 10.2 7.8 0.13 13.1 3.2 1.9 2 1 0 2 2 2 0 DMAP1-binding Domain EMP70 PF02990.16 RKP03453.1 - 1.9e-184 614.2 6.9 1.9e-184 614.2 6.9 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Phage_holin_3_6 PF07332.11 RKP03453.1 - 0.14 12.2 0.0 0.14 12.2 0.0 5.2 3 2 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 RKP03454.1 - 1.8e-07 31.7 3.2 0.055 14.4 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03454.1 - 2.5e-05 24.5 0.0 0.84 10.0 0.0 4.5 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain V-ATPase_G PF03179.15 RKP03454.1 - 0.049 14.2 0.0 0.098 13.2 0.0 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CSD PF00313.22 RKP03455.1 - 2.9e-18 65.5 0.1 4.6e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RKP03455.1 - 0.17 11.6 0.1 0.46 10.2 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain cobW PF02492.19 RKP03456.1 - 4.9e-45 153.3 0.0 5.7e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RKP03456.1 - 0.0026 17.7 0.1 0.011 15.6 0.1 1.9 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 RKP03456.1 - 0.0036 17.4 0.0 0.0051 16.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RKP03456.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 RKP03456.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKP03456.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 RKP03456.1 - 0.025 13.5 0.2 0.035 13.0 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 RKP03456.1 - 0.035 14.3 0.1 0.06 13.6 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RKP03456.1 - 0.036 14.1 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RKP03456.1 - 0.07 13.4 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKP03456.1 - 0.073 12.8 0.2 0.16 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 RKP03456.1 - 0.084 12.8 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 RKP03456.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 RKP03456.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain CactinC_cactus PF09732.9 RKP03459.1 - 2.9e-55 185.6 7.1 4.5e-55 184.9 7.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 RKP03459.1 - 7e-19 68.3 0.1 7e-19 68.3 0.1 1.8 2 0 0 2 2 2 1 Conserved mid region of cactin WRW PF10206.9 RKP03459.1 - 0.088 13.2 1.1 20 5.6 0.2 2.6 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Peptidase_S9_N PF02897.15 RKP03460.1 - 1.3e-66 225.1 0.4 1.6e-66 224.8 0.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RKP03460.1 - 4.9e-54 183.0 0.0 7.4e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 RKP03460.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 RKP03460.1 - 0.0016 18.4 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKP03460.1 - 0.0018 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EMP24_GP25L PF01105.24 RKP03461.1 - 7.4e-40 136.8 0.0 8.6e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RIBIOP_C PF04950.12 RKP03462.1 - 5.8e-98 327.9 0.0 9.9e-98 327.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 RKP03462.1 - 6.3e-16 58.2 0.2 7.4e-15 54.8 0.0 2.7 2 1 0 2 2 2 1 AARP2CN (NUC121) domain Complex1_LYR PF05347.15 RKP03463.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ndc1_Nup PF09531.10 RKP03463.1 - 2.6 6.6 4.5 3 6.4 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Forkhead PF00250.18 RKP03464.1 - 3.4e-27 94.5 1.3 2.9e-13 49.9 0.0 2.8 2 0 0 2 2 2 2 Forkhead domain Exonuc_VII_L PF02601.15 RKP03464.1 - 0.99 8.9 31.8 0.92 9.0 4.5 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4813 PF16072.5 RKP03465.1 - 3.7 7.1 29.1 4.6 6.8 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) COX5B PF01215.19 RKP03467.1 - 5.6e-25 87.5 0.0 6.1e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 RKP03467.1 - 0.014 15.1 0.7 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-CHCC PF10276.9 RKP03467.1 - 0.016 15.2 1.6 0.027 14.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger domain Cys_rich_CPXG PF14255.6 RKP03467.1 - 0.14 12.1 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG Nsp1_C PF05064.13 RKP03468.1 - 0.0022 17.8 0.8 0.004 16.9 0.8 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF5595 PF18077.1 RKP03468.1 - 0.28 11.3 0.3 0.49 10.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) SlyX PF04102.12 RKP03468.1 - 0.68 10.6 6.0 0.62 10.7 4.0 2.0 2 0 0 2 2 2 0 SlyX CX9C PF16860.5 RKP03469.1 - 1.5e-14 53.7 8.3 2.1e-08 34.1 1.1 2.0 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 RKP03469.1 - 3.8e-09 36.5 2.4 0.00096 19.2 0.0 3.1 2 1 1 3 3 3 3 CHCH domain Cmc1 PF08583.10 RKP03469.1 - 1e-08 35.1 6.6 0.00012 22.0 0.6 2.5 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 RKP03469.1 - 3.9e-05 23.9 6.8 0.061 13.7 1.3 3.1 2 1 1 3 3 3 3 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 RKP03469.1 - 0.0002 21.5 6.9 0.031 14.5 0.8 2.6 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein TPR_14 PF13428.6 RKP03469.1 - 0.00046 20.8 0.1 0.53 11.2 0.0 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03469.1 - 0.0034 17.2 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat MTCP1 PF08991.10 RKP03469.1 - 0.0098 16.1 8.1 0.1 12.8 4.3 2.7 1 1 1 2 2 2 1 Mature-T-Cell Proliferation I type GCK PF07802.11 RKP03469.1 - 0.012 16.0 4.4 2.6 8.5 0.3 2.6 1 1 1 2 2 2 0 GCK domain UPF0203 PF05254.12 RKP03469.1 - 0.015 15.5 4.8 1.6 9.1 3.1 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.13 RKP03469.1 - 0.03 14.0 6.5 0.73 9.6 0.5 2.5 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 RKP03469.1 - 0.033 14.4 7.2 1.1 9.6 2.0 2.7 1 1 2 3 3 3 0 Cytochrome oxidase c subunit VIb APP_E2 PF12925.7 RKP03469.1 - 0.061 13.0 0.0 1.6 8.4 0.0 2.0 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein TPR_2 PF07719.17 RKP03469.1 - 0.08 13.1 0.2 8.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03469.1 - 0.095 12.4 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 TPR repeat Pet191_N PF10203.9 RKP03469.1 - 0.1 12.9 9.4 1.6 9.0 5.6 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 tRNA-synt_1b PF00579.25 RKP03470.1 - 9.2e-70 235.3 0.0 1.2e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) IGF2_C PF08365.11 RKP03470.1 - 0.55 10.3 2.1 0.96 9.5 0.1 2.4 3 0 0 3 3 3 0 Insulin-like growth factor II E-peptide NOA36 PF06524.12 RKP03471.1 - 1.5 8.1 31.2 1.5 8.1 31.2 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 RKP03471.1 - 1.5 7.9 36.9 1.5 7.9 36.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 RKP03471.1 - 2 6.6 19.9 2 6.6 19.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 RKP03471.1 - 8.2 4.4 33.0 8.5 4.3 33.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Cyt-b5 PF00173.28 RKP03472.1 - 4.4e-05 23.5 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NDUFA12 PF05071.16 RKP03472.1 - 0.14 13.1 0.1 0.37 11.7 0.0 1.7 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Zip PF02535.22 RKP03473.1 - 2 7.6 15.8 3.3 6.8 15.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 RKP03473.1 - 2.8 7.3 25.8 5.9 6.2 25.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cluap1 PF10234.9 RKP03474.1 - 3.6e-63 213.5 0.0 5.2e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 TFIIA PF03153.13 RKP03474.1 - 0.00034 20.7 8.3 0.00034 20.7 8.3 3.0 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit Fez1 PF06818.15 RKP03474.1 - 0.0041 17.6 7.9 0.0067 16.9 7.9 1.3 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 RKP03474.1 - 0.099 11.5 9.3 0.014 14.3 1.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Aminopep PF10023.9 RKP03474.1 - 0.18 11.1 5.6 0.28 10.5 5.6 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Atg14 PF10186.9 RKP03474.1 - 0.18 10.8 3.2 0.28 10.2 3.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 RKP03474.1 - 0.21 10.1 8.8 0.45 9.0 8.8 1.5 1 1 0 1 1 1 0 Macoilin family Lebercilin PF15619.6 RKP03474.1 - 0.35 10.5 9.0 0.71 9.5 9.0 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 RKP03474.1 - 0.82 9.9 7.0 0.072 13.3 0.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 RKP03474.1 - 0.94 8.7 4.3 3.8 6.7 0.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein Tho2 PF11262.8 RKP03474.1 - 1.3 8.2 2.9 0.78 8.9 0.1 1.7 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ABC_tran_CTD PF16326.5 RKP03474.1 - 1.3 9.3 9.9 3.6 7.9 1.3 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain APG6_N PF17675.1 RKP03474.1 - 3 8.4 13.9 0.15 12.6 1.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region CLZ PF16526.5 RKP03474.1 - 4.8 7.6 6.8 14 6.1 1.6 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SH2_2 PF14633.6 RKP03475.1 - 3.5e-58 196.6 0.0 3.5e-58 196.6 0.0 2.2 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 RKP03475.1 - 1e-18 67.5 0.0 2.3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 RKP03475.1 - 5.4e-18 65.2 0.0 1.2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 RKP03475.1 - 2.3e-10 40.9 31.0 2.3e-10 40.9 31.0 5.0 4 1 1 5 5 5 2 Acidic N-terminal SPT6 HTH_44 PF14641.6 RKP03475.1 - 1.9e-09 38.0 0.1 1.2e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 DUF3432 PF11914.8 RKP03477.1 - 0.0028 17.8 9.3 0.0028 17.8 9.3 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3432) Peptidase_C24 PF03510.14 RKP03477.1 - 0.78 10.3 3.1 6.4 7.3 0.3 2.9 1 1 3 4 4 4 0 2C endopeptidase (C24) cysteine protease family Retinin_C PF04527.12 RKP03477.1 - 1.1 9.6 4.8 16 5.9 4.8 2.7 1 1 0 1 1 1 0 Drosophila Retinin like protein PhoLip_ATPase_C PF16212.5 RKP03478.1 - 1.9e-70 237.4 20.2 1.9e-70 237.4 20.2 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKP03478.1 - 4.4e-24 84.0 1.0 9.8e-24 82.8 0.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RKP03478.1 - 2.1e-11 44.5 0.1 5.7e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP03478.1 - 2e-07 31.0 0.0 1e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RKP03478.1 - 0.0023 17.5 0.0 0.0023 17.5 0.0 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RKP03478.1 - 0.011 15.5 0.2 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 RKP03479.1 - 7.9e-77 258.2 0.0 9.1e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03479.1 - 3.4e-39 134.7 0.0 4e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP03479.1 - 6.4e-09 35.5 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RKP03479.1 - 9.6e-06 25.3 0.2 1.5e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RKP03479.1 - 0.0014 17.6 0.5 0.0019 17.2 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP03479.1 - 0.013 14.8 4.1 0.097 12.0 4.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP03479.1 - 0.089 12.7 0.5 0.23 11.4 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA_11 PF13086.6 RKP03480.1 - 2.1e-58 198.2 0.4 5.2e-58 196.9 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RKP03480.1 - 1.4e-54 184.7 0.0 2e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP03480.1 - 6.6e-14 52.1 1.4 1.1e-07 31.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 RKP03480.1 - 4.9e-10 39.9 0.0 1.1e-08 35.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RKP03480.1 - 1e-09 38.5 0.0 0.0067 16.2 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 RKP03480.1 - 6.6e-06 26.4 0.1 0.0005 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RKP03480.1 - 1.8e-05 24.8 0.0 0.00017 21.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RKP03480.1 - 4.5e-05 23.9 0.3 0.00019 21.9 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 RKP03480.1 - 0.0002 21.8 0.1 0.0025 18.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 RKP03480.1 - 0.00048 19.2 0.0 0.00099 18.1 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 RKP03480.1 - 0.00097 18.4 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 RKP03480.1 - 0.0012 18.8 2.7 0.0025 17.7 0.0 2.5 2 1 0 2 2 2 1 Helicase NTPase_1 PF03266.15 RKP03480.1 - 0.0016 18.4 0.1 0.89 9.4 0.0 2.5 2 0 0 2 2 2 1 NTPase PhoH PF02562.16 RKP03480.1 - 0.0028 17.1 0.0 0.095 12.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 RKP03480.1 - 0.0034 16.7 1.5 0.078 12.2 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 RKP03480.1 - 0.0065 16.2 0.2 0.24 11.1 0.0 3.1 4 0 0 4 4 3 1 IstB-like ATP binding protein SRP54 PF00448.22 RKP03480.1 - 0.0093 15.6 0.0 0.099 12.3 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 RKP03480.1 - 0.0098 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKP03480.1 - 0.012 15.6 0.0 0.044 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RKP03480.1 - 0.013 15.1 0.9 0.29 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 RKP03480.1 - 0.017 14.9 0.2 0.2 11.4 0.2 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 RKP03480.1 - 0.022 15.1 0.0 0.06 13.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 RKP03480.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 RKP03480.1 - 0.032 13.2 0.1 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 RKP03480.1 - 0.033 13.3 0.0 0.08 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 RKP03480.1 - 0.036 14.2 0.6 0.21 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 RKP03480.1 - 0.038 14.0 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 RKP03480.1 - 0.048 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 RKP03480.1 - 0.055 13.2 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 RKP03480.1 - 0.06 13.3 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 1 0 Flavivirus DEAD domain AAA_18 PF13238.6 RKP03480.1 - 0.072 13.6 0.0 0.3 11.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 RKP03480.1 - 0.09 12.5 0.0 0.38 10.5 0.0 2.0 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain UvrD-helicase PF00580.21 RKP03480.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 RKP03480.1 - 0.11 12.3 0.2 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Rad17 PF03215.15 RKP03480.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_31 PF13614.6 RKP03480.1 - 0.2 11.6 0.0 0.73 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mob1_phocein PF03637.17 RKP03481.1 - 6.8e-66 221.5 1.4 7.9e-66 221.2 1.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family zf-HIT PF04438.16 RKP03482.1 - 8.6e-07 28.7 10.9 1.2e-06 28.2 10.9 1.2 1 0 0 1 1 1 1 HIT zinc finger RNA_pol_Rpb8 PF03870.15 RKP03483.1 - 6.3e-50 169.0 0.5 7.1e-50 168.8 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 RKP03483.1 - 3.3e-06 27.1 1.5 0.0011 19.0 0.2 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Carboxyl_trans PF01039.22 RKP03484.1 - 8.9e-115 384.1 0.0 1.1e-114 383.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 RKP03484.1 - 1.9e-74 251.2 0.0 3.5e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 RKP03484.1 - 1.2e-50 172.0 0.0 2.2e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 RKP03484.1 - 1.3e-23 83.6 0.0 4.5e-23 81.9 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 RKP03484.1 - 2.5e-22 79.0 0.0 1e-20 73.9 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 RKP03484.1 - 8.5e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme MHYT PF03707.16 RKP03485.1 - 1.7e-17 63.3 24.9 4e-08 33.3 5.3 5.0 4 1 0 4 4 4 4 Bacterial signalling protein N terminal repeat TPR_2 PF07719.17 RKP03487.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03487.1 - 0.082 12.6 0.2 0.22 11.2 0.1 1.8 1 1 1 2 2 2 0 TPR repeat TPR_1 PF00515.28 RKP03487.1 - 0.093 12.6 1.2 0.3 11.0 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKP03487.1 - 0.12 12.4 0.3 0.21 11.7 0.3 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Branch PF02485.21 RKP03490.1 - 4e-17 62.5 0.4 2.7e-16 59.9 0.1 2.0 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Nucleotid_trans PF03407.16 RKP03490.1 - 2.4e-16 60.4 0.0 4.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Branch PF02485.21 RKP03491.1 - 7.3e-20 71.5 0.2 6.8e-19 68.3 0.2 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Cullin PF00888.22 RKP03492.1 - 1e-135 453.8 0.0 1.4e-135 453.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 RKP03492.1 - 2e-25 88.6 5.6 4.7e-25 87.4 5.6 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 RKP03492.1 - 0.016 15.6 1.0 0.036 14.4 0.2 2.0 2 0 0 2 2 2 0 Penicillinase repressor Roc PF08477.13 RKP03493.1 - 2.5e-12 47.1 0.0 4.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RKP03493.1 - 3.4e-12 46.3 0.0 5.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF3915 PF13054.6 RKP03493.1 - 0.2 11.6 2.3 0.33 10.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RSB_motif PF16294.5 RKP03493.1 - 0.54 10.5 4.3 1.1 9.6 4.3 1.4 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 RKP03494.1 - 5e-19 67.9 0.0 4.1e-16 58.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03494.1 - 0.0011 19.0 0.0 0.0051 16.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 RKP03494.1 - 0.038 13.8 0.0 7.5 6.3 0.0 3.0 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain Hydin_ADK PF17213.3 RKP03494.1 - 8.2 6.7 12.1 15 5.8 12.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Sds3 PF08598.11 RKP03495.1 - 2.2e-06 27.8 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Sds3-like DKCLD PF08068.12 RKP03496.1 - 1.1e-30 105.4 1.3 9.8e-30 102.4 0.8 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 RKP03496.1 - 2.1e-23 82.2 1.0 4e-23 81.3 1.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 RKP03496.1 - 2.1e-22 80.1 0.2 2e-19 70.4 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 RKP03496.1 - 3.1e-19 68.7 1.1 3.1e-19 68.7 1.1 2.2 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 RKP03496.1 - 0.055 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain GAGA_bind PF06217.12 RKP03496.1 - 0.47 10.7 14.4 0.7 10.1 14.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 RKP03496.1 - 1.7 8.7 8.1 2.7 8.1 8.1 1.4 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 RKP03496.1 - 3.1 6.5 12.0 4 6.1 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 RKP03496.1 - 8 6.2 25.9 11 5.7 25.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mit_KHE1 PF10173.9 RKP03497.1 - 1e-13 51.8 0.8 1.8e-13 51.0 0.8 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pkinase PF00069.25 RKP03499.1 - 5.3e-62 209.6 0.0 6.1e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03499.1 - 4.7e-47 160.4 0.0 5.5e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP03499.1 - 0.00029 20.3 0.0 0.0054 16.1 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 RKP03499.1 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKP03499.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RKP03499.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RKP03499.1 - 0.033 14.1 0.1 3 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cytidylate_kin PF02224.18 RKP03501.1 - 5.6e-52 176.5 0.0 9.7e-52 175.8 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 RKP03501.1 - 0.0022 18.2 0.6 0.0083 16.3 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RKP03501.1 - 0.013 15.9 0.1 0.1 13.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 RKP03501.1 - 0.019 15.1 0.2 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_18 PF13238.6 RKP03501.1 - 0.11 13.1 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain GrpB PF04229.14 RKP03501.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 GrpB protein AAA_6 PF12774.7 RKP03501.1 - 0.23 10.4 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region zf-C2H2_4 PF13894.6 RKP03502.1 - 3.2e-07 30.6 3.6 0.0051 17.6 0.5 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP03502.1 - 1.2e-06 28.7 0.3 0.0023 18.3 0.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 RKP03502.1 - 0.011 15.7 0.2 0.011 15.7 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Band_7 PF01145.25 RKP03503.1 - 3.2e-22 79.4 3.4 4.4e-22 78.9 3.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 RKP03503.1 - 0.02 15.1 0.5 0.034 14.3 0.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 TFIIF_alpha PF05793.12 RKP03504.1 - 5.7e-11 41.7 40.4 5.7e-11 41.7 40.4 3.7 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cpn10 PF00166.21 RKP03505.1 - 5.3e-27 93.7 0.0 5.8e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MMM1 PF10296.9 RKP03506.1 - 6.5e-41 140.5 0.0 3.1e-35 121.8 0.0 3.3 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 GHMP_kinases_N PF00288.26 RKP03507.1 - 7.7e-10 38.9 0.7 1.7e-09 37.8 0.7 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RKP03507.1 - 0.0028 18.0 0.0 0.0075 16.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Pkinase PF00069.25 RKP03509.1 - 1.6e-33 116.2 0.0 1.7e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03509.1 - 9.8e-20 70.9 0.0 1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKP03509.1 - 0.0069 16.3 0.4 0.015 15.2 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP03509.1 - 0.042 13.2 0.0 0.057 12.7 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RKP03509.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ferric_reduct PF01794.19 RKP03510.1 - 5.9e-20 71.7 13.7 5.9e-20 71.7 13.7 2.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RKP03510.1 - 6.7e-14 51.9 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 RKP03510.1 - 1.6e-08 34.8 0.0 2.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 RKP03510.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Luteo_PO PF04662.13 RKP03510.1 - 0.5 10.0 2.1 7.5 6.2 2.1 2.2 1 1 0 1 1 1 0 Luteovirus P0 protein DUF5090 PF17009.5 RKP03510.1 - 3.8 7.4 6.2 8.1 6.4 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Macoilin PF09726.9 RKP03511.1 - 6.5 5.2 6.4 8 4.9 6.4 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_M16_M PF16187.5 RKP03512.1 - 4.9e-59 199.9 0.0 7.6e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 RKP03512.1 - 2e-38 131.7 0.0 4e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RKP03512.1 - 7.6e-28 97.8 0.0 7e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Clr2_transil PF16761.5 RKP03512.1 - 0.022 15.6 0.0 12 6.8 0.0 3.4 3 0 0 3 3 3 0 Transcription-silencing protein, cryptic loci regulator Clr2 Spb1_C PF07780.12 RKP03513.1 - 3.5e-61 206.5 12.6 3.5e-61 206.5 12.6 2.8 2 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 RKP03513.1 - 2.9e-54 183.9 0.0 5.3e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 RKP03513.1 - 1.2e-34 119.5 0.4 1.2e-34 119.5 0.4 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 RKP03513.1 - 0.065 13.1 0.0 0.32 10.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain EF1_GNE PF00736.19 RKP03514.1 - 6.5e-34 116.0 1.2 6.5e-34 116.0 1.2 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 RKP03514.1 - 1.6e-15 57.2 4.8 1.6e-15 57.2 4.8 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 RKP03514.1 - 0.00074 19.3 1.2 0.001 18.9 1.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GST_C_3 PF14497.6 RKP03514.1 - 0.01 16.0 0.2 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RKP03514.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 RKP03514.1 - 0.034 14.7 2.2 0.054 14.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) NOP5NT PF08156.13 RKP03514.1 - 0.076 13.4 0.1 0.37 11.2 0.1 2.2 1 1 0 1 1 1 0 NOP5NT (NUC127) domain YL1 PF05764.13 RKP03514.1 - 0.17 11.9 6.6 0.22 11.6 6.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein FYRC PF05965.14 RKP03515.1 - 1.5e-11 44.3 0.0 3.7e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 RKP03515.1 - 4.2e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus LST1 PF05083.13 RKP03515.1 - 0.042 14.1 0.9 0.076 13.3 0.5 1.7 1 1 0 1 1 1 0 LST-1 protein Suf PF05843.14 RKP03515.1 - 0.18 11.7 2.9 0.27 11.2 2.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3c_N PF05470.12 RKP03515.1 - 1.1 7.5 2.8 1.5 7.0 2.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GREB1 PF15782.5 RKP03515.1 - 5.9 3.9 8.3 7.4 3.5 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ank_2 PF12796.7 RKP03516.1 - 6.5e-05 23.5 0.2 0.00011 22.7 0.2 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKP03516.1 - 0.00012 22.2 2.5 0.0012 19.1 0.2 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 RKP03516.1 - 0.00034 20.9 0.1 0.00034 20.9 0.1 2.2 2 1 1 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 RKP03516.1 - 0.0013 19.0 0.3 0.011 16.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 RKP03516.1 - 0.076 13.6 0.3 0.42 11.3 0.3 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) VPS13 PF16908.5 RKP03518.1 - 1.1e-68 231.5 0.1 2.8e-64 217.2 0.0 4.2 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 RKP03518.1 - 3e-68 229.1 5.6 2.7e-64 216.2 0.8 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 RKP03518.1 - 8.9e-58 195.8 0.0 3e-55 187.5 0.0 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 RKP03518.1 - 2e-40 138.7 0.3 1.9e-37 128.9 0.1 3.3 3 0 0 3 3 3 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 RKP03518.1 - 4.9e-37 126.6 0.2 1.5e-36 125.0 0.2 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 RKP03518.1 - 2.2e-09 37.5 0.0 2.1e-08 34.4 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 RKP03518.1 - 1.2e-06 27.7 0.3 1.2e-06 27.7 0.3 2.6 2 1 1 3 3 3 1 Golgi-body localisation protein domain ANAPC4 PF12896.7 RKP03519.1 - 0.004 16.7 0.1 0.014 14.9 0.0 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 HSP20 PF00011.21 RKP03520.1 - 5.4e-09 36.1 0.0 9.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RKP03520.1 - 6.9e-06 25.5 0.1 3.6e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Phage_holin_2_4 PF16082.5 RKP03521.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ras PF00071.22 RKP03522.1 - 3e-59 199.2 0.4 3.7e-59 198.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKP03522.1 - 5.9e-34 116.9 0.2 9.4e-34 116.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKP03522.1 - 1.9e-12 47.0 0.1 2.6e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKP03522.1 - 4.9e-07 29.8 0.1 9.4e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP03522.1 - 0.017 14.7 0.0 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.27 RKP03522.1 - 0.017 14.6 0.1 0.1 12.2 0.1 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 RKP03522.1 - 0.019 14.4 0.1 0.041 13.3 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKP03522.1 - 0.031 13.6 0.0 0.043 13.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_32 PF13654.6 RKP03522.1 - 0.04 12.7 0.0 0.067 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RKP03522.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 RKP03522.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Serglycin PF04360.12 RKP03523.1 - 0.16 11.9 1.0 0.39 10.6 1.0 1.6 1 0 0 1 1 1 0 Serglycin TPR_2 PF07719.17 RKP03524.1 - 0.023 14.8 0.6 0.44 10.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03524.1 - 0.031 14.6 0.1 0.51 10.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03524.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP03524.1 - 0.13 12.2 0.6 1 9.3 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S8 PF00082.22 RKP03525.1 - 5.3e-38 131.0 3.1 6.6e-38 130.7 3.1 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 RKP03525.1 - 3.5e-23 81.4 0.3 6.8e-23 80.5 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 RKP03525.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family SRP_TPR_like PF17004.5 RKP03526.1 - 2.7e-06 27.4 0.0 8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 RKP03526.1 - 0.0026 18.1 6.2 0.0063 16.9 6.2 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_7 PF13176.6 RKP03526.1 - 0.052 13.6 0.1 0.052 13.6 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03526.1 - 0.16 12.3 0.1 0.16 12.3 0.1 5.5 7 2 0 7 7 7 0 Tetratricopeptide repeat DUF2383 PF09537.10 RKP03526.1 - 0.37 11.1 1.4 10 6.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) TPR_16 PF13432.6 RKP03526.1 - 0.39 11.4 30.9 0.42 11.3 1.2 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03526.1 - 0.97 10.0 18.4 0.22 12.1 0.3 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat YfdX PF10938.8 RKP03526.1 - 2 8.3 8.3 7.9 6.4 0.1 2.9 2 0 0 2 2 2 0 YfdX protein TPR_10 PF13374.6 RKP03526.1 - 5.2 7.1 11.4 0.33 10.9 0.9 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 RKP03528.1 - 1.5e-11 44.3 12.6 0.04 14.3 0.0 6.1 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP03528.1 - 1.5e-06 27.9 18.8 0.45 10.3 3.6 5.6 3 1 2 6 6 6 5 Leucine rich repeat Ribosomal_L14 PF00238.19 RKP03529.1 - 4e-44 149.6 1.2 4.4e-44 149.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e CS PF04969.16 RKP03530.1 - 2.1e-19 70.3 0.3 4.4e-19 69.3 0.1 1.7 2 0 0 2 2 2 1 CS domain PAP2 PF01569.21 RKP03531.1 - 2.9e-27 95.1 4.4 2.9e-27 95.1 4.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 RKP03531.1 - 0.0085 16.6 0.7 0.0085 16.6 0.7 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF805 PF05656.14 RKP03531.1 - 0.019 15.4 7.8 0.25 11.7 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PAP2_3 PF14378.6 RKP03531.1 - 2.7 7.6 14.9 1.4 8.6 9.9 2.7 1 1 0 2 2 2 0 PAP2 superfamily zf-Tim10_DDP PF02953.15 RKP03532.1 - 2.1e-17 62.5 2.1 2.5e-17 62.3 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 RKP03532.1 - 0.016 14.9 1.0 0.02 14.6 1.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Methyltransf_28 PF02636.17 RKP03533.1 - 1.3e-35 123.3 0.0 2.1e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 RKP03533.1 - 0.055 14.2 0.0 0.18 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTHFR PF02219.17 RKP03534.1 - 3.6e-118 394.1 0.0 5.1e-118 393.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase 2Fe-2S_thioredx PF01257.19 RKP03535.1 - 8.8e-59 197.5 0.1 1e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin VCBS PF13517.6 RKP03536.1 - 4.5e-24 84.8 5.6 2.1e-08 34.6 0.0 5.3 5 0 0 5 5 5 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 RKP03536.1 - 1.1e-06 28.1 1.0 0.63 9.4 0.0 4.3 3 1 1 4 4 4 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 RKP03536.1 - 6e-05 23.1 10.6 4.9 7.4 0.0 6.1 6 0 0 6 6 6 3 FG-GAP repeat PliI PF16743.5 RKP03536.1 - 0.014 15.2 0.8 1.1e+02 2.5 0.0 5.1 6 0 0 6 6 6 0 Periplasmic lysozyme inhibitor of I-type lysozyme ABC_membrane PF00664.23 RKP03537.1 - 3.7e-37 128.5 8.5 4.6e-37 128.1 8.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKP03537.1 - 1.4e-33 116.3 0.0 2.9e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RKP03537.1 - 0.002 18.5 0.1 0.0052 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 RKP03537.1 - 0.0022 17.9 0.1 0.074 12.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Cytidylate_kin PF02224.18 RKP03537.1 - 0.0027 17.5 0.3 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase SMC_N PF02463.19 RKP03537.1 - 0.014 14.8 0.0 2.4 7.5 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 RKP03537.1 - 0.014 15.4 0.0 0.068 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKP03537.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 RKP03537.1 - 0.022 14.5 0.1 0.059 13.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 RKP03537.1 - 0.027 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 RKP03537.1 - 0.039 13.7 0.0 0.2 11.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 RKP03537.1 - 0.044 14.3 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ribonuc_red_sm PF00268.21 RKP03537.1 - 0.047 13.1 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain MMR_HSR1 PF01926.23 RKP03537.1 - 0.059 13.5 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 RKP03537.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 RKP03537.1 - 0.12 12.5 0.0 0.49 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 RKP03537.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 RKP03537.1 - 0.15 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 RKP03537.1 - 6 6.4 10.9 9.7 5.7 10.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_16 PF10294.9 RKP03539.1 - 1.4e-11 44.4 0.0 2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RKP03539.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 RKP03539.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G ADH_zinc_N PF00107.26 RKP03539.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Tmemb_14 PF03647.13 RKP03540.1 - 1.8e-22 79.9 8.4 2e-22 79.7 8.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 RKP03540.1 - 4.7e-05 23.6 2.7 4.7e-05 23.6 2.7 1.5 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 Gram_pos_anchor PF00746.21 RKP03540.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.5 4 0 0 4 4 4 0 LPXTG cell wall anchor motif DAO PF01266.24 RKP03541.1 - 8.6e-50 170.3 0.1 1.4e-49 169.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 RKP03541.1 - 7.2e-45 151.9 0.1 1.3e-44 151.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 RKP03541.1 - 2.3e-05 23.9 0.6 4.4e-05 23.0 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RKP03541.1 - 0.00013 21.2 4.0 0.00041 19.5 0.8 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 RKP03541.1 - 0.00029 21.0 0.3 0.001 19.2 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RKP03541.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 RKP03541.1 - 0.003 18.0 0.1 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair HI0933_like PF03486.14 RKP03541.1 - 0.014 14.1 0.5 0.023 13.4 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 RKP03541.1 - 0.02 14.0 0.4 0.26 10.3 0.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A EF-hand_6 PF13405.6 RKP03541.1 - 0.027 14.4 0.1 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 RKP03541.1 - 0.027 14.0 0.7 0.46 10.2 0.0 3.0 3 0 0 3 3 3 0 EF hand FAD_binding_3 PF01494.19 RKP03541.1 - 0.067 12.4 0.2 0.48 9.6 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 RKP03541.1 - 0.08 12.2 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKP03541.1 - 0.08 13.5 0.4 0.28 11.8 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RKP03541.1 - 0.15 11.3 0.2 0.29 10.3 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.25 RKP03542.1 - 1.4e-43 149.2 0.0 1.5e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03542.1 - 3.2e-15 56.1 0.0 4.1e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP03542.1 - 4e-05 23.1 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP03542.1 - 0.00036 20.0 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CIA30 PF08547.12 RKP03543.1 - 4e-37 127.7 0.0 4.9e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 RKP03543.1 - 0.00083 19.4 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain NGP1NT PF08153.12 RKP03544.1 - 2.1e-48 163.8 0.1 3e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 RKP03544.1 - 3.9e-18 65.6 0.0 3.3e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 RKP03544.1 - 1.2e-06 28.1 0.0 3.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RKP03544.1 - 8.4e-06 25.8 0.0 2.2e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 RKP03544.1 - 1.6e-05 24.5 0.1 0.031 13.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 RKP03544.1 - 0.0088 16.1 0.3 2.2 8.3 0.1 3.5 3 1 1 4 4 4 1 Dynamin family Roc PF08477.13 RKP03544.1 - 0.044 14.0 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 RKP03544.1 - 0.099 12.2 0.0 1.8 8.1 0.0 2.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DnaJ PF00226.31 RKP03545.1 - 1.7e-19 69.7 2.5 1.9e-19 69.6 0.6 2.1 3 0 0 3 3 2 1 DnaJ domain TPR_2 PF07719.17 RKP03545.1 - 5e-15 54.3 7.9 0.043 13.9 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03545.1 - 9e-12 44.3 0.0 1.5 8.8 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 RKP03545.1 - 1e-10 42.0 16.8 6.8e-05 23.4 0.0 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03545.1 - 1.9e-10 40.1 0.3 0.096 12.9 0.1 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP03545.1 - 5.2e-10 39.3 9.4 1.5e-05 25.0 0.1 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 RKP03545.1 - 1.1e-09 37.8 0.0 0.00039 20.0 0.0 4.3 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 RKP03545.1 - 3.4e-09 36.8 21.6 0.017 15.9 0.2 6.5 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03545.1 - 3.4e-09 37.1 10.6 0.46 11.0 1.8 5.3 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03545.1 - 3.9e-07 30.3 17.2 0.0094 16.2 0.7 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03545.1 - 2.2e-06 27.7 0.0 0.12 12.8 0.0 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 RKP03545.1 - 0.012 15.9 9.7 0.15 12.4 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 RKP03545.1 - 0.036 13.8 12.3 0.23 11.1 0.1 4.2 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF627 PF04781.12 RKP03545.1 - 0.043 13.8 1.3 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.6 RKP03545.1 - 0.046 13.8 0.0 8.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 RKP03545.1 - 0.069 13.8 20.7 0.21 12.3 0.4 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DHC_N2 PF08393.13 RKP03545.1 - 0.076 12.1 0.0 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Alkyl_sulf_dimr PF14863.6 RKP03545.1 - 0.096 13.1 5.3 3.3 8.2 0.2 3.0 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation DUF5113 PF17140.4 RKP03545.1 - 0.18 11.6 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_7 PF13176.6 RKP03545.1 - 0.3 11.2 6.7 34 4.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03545.1 - 1 10.2 9.6 32 5.4 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP03545.1 - 1 9.6 6.1 3.5 7.9 0.0 3.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Pirin PF02678.16 RKP03546.1 - 2.5e-26 91.8 0.0 4.2e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 RKP03546.1 - 9.5e-26 90.2 0.0 3.3e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 RKP03546.1 - 0.0013 18.4 0.2 0.25 11.1 0.3 2.6 3 0 0 3 3 3 2 Cupin domain Bromo_TP PF07524.13 RKP03547.1 - 8.4e-11 41.7 0.0 2.3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated PHD PF00628.29 RKP03547.1 - 4e-09 36.2 7.0 6.4e-09 35.6 7.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKP03547.1 - 1.3e-05 24.6 1.6 2e-05 24.0 1.6 1.3 1 0 0 1 1 1 1 PHD-finger Bromo_TP_like PF17027.5 RKP03547.1 - 0.049 13.8 0.1 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Histone-fold protein Pet191_N PF10203.9 RKP03548.1 - 4e-17 62.3 2.1 4.8e-17 62.0 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Ndufs5 PF10200.9 RKP03548.1 - 0.17 12.2 0.9 0.66 10.3 0.2 1.9 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa IL11 PF07400.11 RKP03549.1 - 0.019 14.6 1.1 0.073 12.7 0.1 2.2 2 0 0 2 2 2 0 Interleukin 11 PRIMA1 PF16101.5 RKP03549.1 - 0.31 11.1 6.7 1.2 9.2 6.7 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 RKP03549.1 - 0.78 9.8 4.9 0.18 11.9 1.1 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DSHCT PF08148.12 RKP03550.1 - 1.9e-52 177.2 0.4 3.8e-52 176.3 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 RKP03550.1 - 1.3e-42 146.6 0.0 2.1e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 RKP03550.1 - 6.1e-19 68.5 0.0 3.5e-18 66.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP03550.1 - 4.1e-07 30.3 0.0 5.2e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP03550.1 - 0.00033 20.7 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RKP03550.1 - 0.053 13.8 0.0 0.36 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 RKP03550.1 - 0.086 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rtf2 PF04641.12 RKP03551.1 - 5.1e-38 130.9 0.0 7.1e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 RKP03551.1 - 0.16 11.8 0.9 0.52 10.2 0.0 2.2 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit SIR2 PF02146.17 RKP03552.1 - 1.2e-31 110.0 0.0 1.7e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 RKP03552.1 - 0.02 14.6 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain BRE1 PF08647.11 RKP03553.1 - 4.4e-06 26.7 9.6 4.4e-06 26.7 9.6 4.1 2 2 1 3 3 3 1 BRE1 E3 ubiquitin ligase DMPK_coil PF08826.10 RKP03553.1 - 0.036 14.2 1.3 0.036 14.2 1.3 5.1 5 1 0 5 5 5 0 DMPK coiled coil domain like DUF1192 PF06698.11 RKP03553.1 - 1.1 9.3 9.4 1.7 8.8 0.7 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) DUF948 PF06103.11 RKP03553.1 - 1.4 9.2 12.9 0.44 10.8 0.4 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 RKP03553.1 - 2.7 8.5 6.3 1.8 9.1 0.4 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 RKP03553.1 - 6.4 6.6 29.7 2.2 8.1 6.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) ADIP PF11559.8 RKP03553.1 - 9.3 6.3 36.8 0.42 10.7 9.3 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ThrE PF06738.12 RKP03554.1 - 5.4e-36 124.2 15.6 1.4e-21 76.9 2.6 3.3 3 0 0 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 RKP03554.1 - 5.3e-05 23.4 2.3 5.3e-05 23.4 2.3 3.9 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE STE3 PF02076.15 RKP03555.1 - 7e-13 48.4 10.6 1.4e-10 40.9 5.3 2.4 2 1 0 2 2 2 2 Pheromone A receptor COX14 PF14880.6 RKP03555.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.4 3 0 0 3 3 3 0 Cytochrome oxidase c assembly FtsX PF02687.21 RKP03555.1 - 3.3 8.2 13.9 3.3 8.2 3.4 3.4 3 0 0 3 3 3 0 FtsX-like permease family Mito_carr PF00153.27 RKP03556.1 - 1.2e-60 201.5 3.7 1.1e-19 70.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3123 PF11321.8 RKP03556.1 - 0.055 14.1 0.6 0.1 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) CS PF04969.16 RKP03557.1 - 2.8e-06 28.2 0.0 3.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 RKP03557.1 - 0.015 15.9 17.9 0.026 15.2 17.9 1.4 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.11 RKP03557.1 - 0.1 10.6 2.6 0.12 10.4 2.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MPC PF03650.13 RKP03559.1 - 3e-30 104.6 0.2 3.1e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Kelch_5 PF13854.6 RKP03560.1 - 4.2e-36 122.4 10.6 3.6e-06 26.8 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 RKP03560.1 - 9.4e-34 115.2 12.4 2.9e-09 36.8 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 RKP03560.1 - 3.2e-32 109.9 6.7 6.7e-07 28.8 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 RKP03560.1 - 3.3e-29 100.6 18.4 5.7e-08 32.8 0.0 7.3 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 RKP03560.1 - 1.9e-23 81.9 14.1 1.8e-06 28.0 0.0 6.2 3 2 3 6 6 6 5 Kelch motif Kelch_2 PF07646.15 RKP03560.1 - 3.8e-22 77.3 7.1 0.0004 20.2 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Zw10 PF06248.13 RKP03562.1 - 0.063 11.8 0.0 0.082 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF4210 PF13915.6 RKP03563.1 - 2.7e-27 95.2 0.1 5.8e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 RKP03563.1 - 2.2e-08 34.1 0.0 5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis Laminin_EGF PF00053.24 RKP03564.1 - 0.019 15.1 10.2 0.019 15.1 10.2 4.6 2 2 1 3 3 3 0 Laminin EGF domain Ribosomal_L34e PF01199.18 RKP03565.1 - 1.1e-40 137.8 3.8 1.6e-40 137.3 3.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FKBP_C PF00254.28 RKP03566.1 - 5.6e-31 106.7 0.0 7.1e-31 106.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ATP_sub_h PF10775.9 RKP03567.1 - 6.5e-10 38.9 1.0 1e-09 38.2 1.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h EMP70 PF02990.16 RKP03568.1 - 1.3e-149 499.2 0.4 1.6e-149 498.9 0.4 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 FeS_assembly_P PF01883.19 RKP03570.1 - 3.2e-16 59.3 0.1 5.4e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CDC50 PF03381.15 RKP03571.1 - 1.8e-87 293.4 0.0 2.2e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pyr_redox_2 PF07992.14 RKP03572.1 - 9.5e-26 90.7 0.0 3.3e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKP03572.1 - 3.1e-16 59.7 0.0 2.6e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RKP03572.1 - 0.00031 19.7 0.0 0.00058 18.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 RKP03572.1 - 0.0071 15.4 0.3 0.91 8.5 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 RKP03572.1 - 0.0072 16.5 2.1 0.068 13.4 0.1 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 RKP03572.1 - 0.013 14.6 0.0 0.56 9.3 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 RKP03572.1 - 0.031 13.5 0.0 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PQ-loop PF04193.14 RKP03572.1 - 0.047 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 PQ loop repeat HI0933_like PF03486.14 RKP03572.1 - 0.089 11.5 0.1 0.22 10.2 0.1 1.7 1 0 0 1 1 1 0 HI0933-like protein RGS PF00615.19 RKP03572.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain Robl_LC7 PF03259.17 RKP03574.1 - 3e-15 55.7 0.0 3.2e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DNA_gyraseA_C PF03989.13 RKP03574.1 - 0.1 12.1 0.0 16 5.1 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Pkinase PF00069.25 RKP03575.1 - 6.1e-64 215.9 0.0 7e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03575.1 - 7.4e-30 104.1 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP03575.1 - 1.5e-06 27.8 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKP03575.1 - 0.028 13.2 0.0 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 RKP03575.1 - 0.09 11.7 0.0 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain CSN8_PSD8_EIF3K PF10075.9 RKP03576.1 - 6.4e-15 55.4 0.1 9.3e-14 51.6 0.1 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Pribosyltran PF00156.27 RKP03577.1 - 2.6e-14 53.1 0.1 3.9e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SAYSvFN PF10260.9 RKP03578.1 - 7e-12 45.1 1.8 4.1e-11 42.6 1.8 1.9 1 1 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Chs7 PF12271.8 RKP03579.1 - 2.7e-113 378.1 20.5 3.2e-113 377.9 20.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone ATG27 PF09451.10 RKP03579.1 - 0.16 11.8 0.3 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Phage_holin_2_2 PF10746.9 RKP03579.1 - 0.18 11.5 1.1 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II CN_hydrolase PF00795.22 RKP03580.1 - 3.9e-61 206.7 0.4 4.4e-61 206.5 0.4 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP11 PF06644.11 RKP03581.1 - 5.4e-54 183.8 0.0 6.2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Phage_sheath_1 PF04984.14 RKP03581.1 - 0.15 11.9 1.5 1.6 8.6 0.3 2.2 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain SelR PF01641.18 RKP03582.1 - 6.9e-49 165.0 0.0 7.9e-49 164.8 0.0 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.14 RKP03582.1 - 0.028 14.7 0.2 0.28 11.5 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ADD_ATRX PF17981.1 RKP03582.1 - 0.13 12.2 0.3 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 Cysteine Rich ADD domain DZR PF12773.7 RKP03582.1 - 0.59 10.2 4.0 7.8 6.6 0.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.14 RKP03583.1 - 1.6e-13 50.8 1.9 1.9e-13 50.5 1.9 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 RKP03583.1 - 0.023 14.9 0.8 0.036 14.3 0.8 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Guanylate_kin PF00625.21 RKP03585.1 - 1.2e-54 184.8 0.0 1.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 RKP03585.1 - 2e-08 34.5 0.1 1.5e-07 31.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKP03585.1 - 9.7e-06 25.9 0.0 1.8e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP03585.1 - 6.5e-05 23.5 0.3 0.00029 21.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 RKP03585.1 - 8.4e-05 22.6 0.0 0.00027 21.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RKP03585.1 - 9.2e-05 22.9 0.2 0.00017 22.0 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 RKP03585.1 - 0.00061 20.3 0.0 0.0013 19.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 RKP03585.1 - 0.0017 18.7 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 RKP03585.1 - 0.0033 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RKP03585.1 - 0.0047 16.8 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 RKP03585.1 - 0.005 17.1 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 RKP03585.1 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 RKP03585.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 RKP03585.1 - 0.014 15.9 0.0 0.035 14.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 RKP03585.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Rad17 PF03215.15 RKP03585.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_21 PF13304.6 RKP03585.1 - 0.025 14.4 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system KTI12 PF08433.10 RKP03585.1 - 0.031 13.7 0.0 0.064 12.7 0.0 1.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.19 RKP03585.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RKP03585.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RKP03585.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RKP03585.1 - 0.045 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RKP03585.1 - 0.046 13.3 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 RKP03585.1 - 0.061 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 RKP03585.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 RKP03585.1 - 0.076 12.1 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 RKP03585.1 - 0.082 12.9 0.0 0.35 10.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 RKP03585.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 RKP03585.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase NTPase_1 PF03266.15 RKP03585.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 RKP03585.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 RKP03585.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 RKP03585.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.18 RKP03585.1 - 0.13 11.6 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 RKP03585.1 - 0.16 12.4 0.0 0.6 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 RKP03585.1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FA_desaturase PF00487.24 RKP03587.1 - 4.9e-24 85.5 16.4 8.9e-24 84.7 16.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 RKP03587.1 - 6.6e-09 35.1 0.1 1.5e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF1335 PF07056.11 RKP03587.1 - 0.082 13.0 0.2 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) SLT PF01464.20 RKP03587.1 - 0.18 11.4 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain PP2C PF00481.21 RKP03588.1 - 1.5e-29 103.5 0.0 1.7e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L37ae PF01780.19 RKP03590.1 - 2e-41 140.0 12.1 2.2e-41 139.8 12.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 RKP03590.1 - 0.0019 18.1 2.4 0.0032 17.4 2.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 RKP03590.1 - 0.02 14.9 0.9 0.028 14.5 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-RING_13 PF17977.1 RKP03590.1 - 0.028 14.6 2.8 0.039 14.1 2.8 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Elf1 PF05129.13 RKP03590.1 - 0.03 14.3 2.6 0.044 13.8 2.6 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2175 PF09943.9 RKP03590.1 - 0.12 12.7 2.7 9.8 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) YyzF PF14116.6 RKP03590.1 - 0.14 12.2 1.6 0.34 11.0 0.3 1.9 2 0 0 2 2 2 0 YyzF-like protein C1_2 PF03107.16 RKP03590.1 - 0.3 11.5 2.7 1.9 8.9 2.9 1.9 1 1 1 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.10 RKP03590.1 - 0.57 10.3 2.9 1.6 8.9 2.9 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.15 RKP03590.1 - 0.64 10.1 9.0 3.9 7.6 3.0 2.3 1 1 1 2 2 2 0 BED zinc finger zf-Sec23_Sec24 PF04810.15 RKP03590.1 - 1.6 8.8 4.9 7.2 6.7 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 RKP03590.1 - 4.9 7.8 12.0 5.6 7.6 0.8 2.9 2 1 1 3 3 3 0 Zinc-finger double domain DUF4381 PF14316.6 RKP03591.1 - 0.04 14.1 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sugar_tr PF00083.24 RKP03592.1 - 2.9e-93 313.2 27.6 3.3e-93 313.0 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RKP03592.1 - 1.7e-20 73.3 57.6 9.6e-16 57.6 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_C PF00137.21 RKP03592.1 - 4.2 7.8 18.1 0.57 10.6 1.8 4.0 4 1 0 4 4 4 0 ATP synthase subunit C Fis1_TPR_C PF14853.6 RKP03593.1 - 6.9e-23 80.5 1.5 1e-22 79.9 1.5 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 RKP03593.1 - 3.1e-15 55.5 0.0 4.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 RKP03593.1 - 0.00028 21.3 0.1 0.00046 20.6 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03593.1 - 0.0055 16.7 1.5 0.0055 16.7 1.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03593.1 - 0.037 14.7 2.4 0.11 13.2 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP03593.1 - 0.05 13.8 0.1 0.083 13.1 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RKP03593.1 - 0.093 13.0 1.8 0.22 11.8 1.6 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKP03593.1 - 0.11 12.6 1.8 0.15 12.2 0.8 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03593.1 - 0.24 11.3 2.6 0.37 10.7 1.7 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKP03593.1 - 0.5 10.3 3.4 0.53 10.2 1.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SAICAR_synt PF01259.18 RKP03594.1 - 3.1e-97 325.1 0.0 3.7e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Spec3 PF15795.5 RKP03594.1 - 0.028 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein DUF1192 PF06698.11 RKP03594.1 - 0.046 13.8 1.3 0.086 12.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Methyltransf_12 PF08242.12 RKP03595.1 - 0.0089 16.8 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP03595.1 - 0.048 14.4 0.0 0.062 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 RKP03595.1 - 0.064 13.1 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.20 RKP03596.1 - 2e-90 303.8 0.1 5.6e-69 233.1 0.0 2.0 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 RKP03596.1 - 3.4e-17 62.9 0.2 7.6e-16 58.6 0.3 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP03596.1 - 5.9e-05 23.4 0.9 5.9e-05 23.4 0.9 5.3 4 2 2 6 6 6 1 HEAT repeats Arm PF00514.23 RKP03596.1 - 0.67 10.1 2.9 6.6 6.9 0.0 3.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RKP03596.1 - 4.3 7.9 12.5 5.7 7.5 0.1 5.9 7 0 0 7 7 7 0 HEAT repeat RasGEF PF00617.19 RKP03597.1 - 1.5e-29 103.5 0.0 3.9e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 RKP03597.1 - 0.14 12.5 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 RasGEF N-terminal motif Atg14 PF10186.9 RKP03599.1 - 5.9e-07 28.9 3.3 2.8e-06 26.6 3.3 1.8 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 RKP03599.1 - 8.2 5.7 13.6 8.4 5.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-H2C2_2 PF13465.6 RKP03601.1 - 1.1e-15 57.3 6.9 7.4e-09 35.6 1.1 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKP03601.1 - 1.2e-14 53.8 15.2 1.3e-05 25.4 0.6 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP03601.1 - 3.8e-10 39.7 12.8 0.0008 20.0 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 RKP03601.1 - 2.9e-07 30.7 2.9 0.069 13.6 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 RKP03601.1 - 3.7e-07 30.3 0.9 0.056 13.7 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKP03601.1 - 1.2e-05 25.2 6.4 0.034 14.1 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 RKP03601.1 - 0.00057 19.4 0.3 0.23 11.1 0.1 2.2 1 1 1 2 2 2 2 MYST family zinc finger domain zf-BED PF02892.15 RKP03601.1 - 0.0055 16.7 1.9 0.49 10.5 0.5 2.6 1 1 2 3 3 3 1 BED zinc finger zf_UBZ PF18439.1 RKP03601.1 - 0.0096 15.5 0.8 0.024 14.2 0.1 2.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-CHY PF05495.12 RKP03601.1 - 0.011 16.2 1.7 0.02 15.4 1.7 1.5 1 1 0 1 1 1 0 CHY zinc finger zf-LYAR PF08790.11 RKP03601.1 - 0.013 15.4 5.7 5.6 7.0 0.1 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn_Tnp_IS1595 PF12760.7 RKP03601.1 - 0.021 14.8 3.0 0.52 10.3 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 RKP03601.1 - 0.031 14.5 1.8 0.18 12.1 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon zf-Di19 PF05605.12 RKP03601.1 - 0.042 14.1 3.5 0.052 13.9 2.5 1.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding C1_4 PF07975.12 RKP03601.1 - 0.053 13.8 2.5 0.81 10.0 1.8 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-Sec23_Sec24 PF04810.15 RKP03601.1 - 0.054 13.5 1.0 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger GAGA PF09237.11 RKP03601.1 - 0.065 13.0 1.6 5.1 7.0 0.2 2.3 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.7 RKP03601.1 - 0.072 13.4 1.6 5.6 7.4 0.3 2.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 RKP03601.1 - 0.29 11.6 7.8 27 5.3 8.1 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 RKP03601.1 - 0.35 10.6 4.9 0.75 9.5 0.1 2.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain C5HCH PF17982.1 RKP03601.1 - 0.43 10.8 5.1 1.2 9.4 4.9 1.8 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-AN1 PF01428.16 RKP03601.1 - 1.4 9.1 7.0 6.1 7.1 1.2 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_11 PF16622.5 RKP03601.1 - 1.6 8.6 7.5 9 6.2 0.1 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Vac7 PF12751.7 RKP03602.1 - 0.07 12.6 0.6 0.13 11.7 0.6 1.4 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 HATPase_c PF02518.26 RKP03603.1 - 8.2e-20 71.4 0.0 1.2e-15 57.9 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 RKP03603.1 - 5.1e-18 64.9 0.0 1.4e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 RKP03603.1 - 6.4e-16 58.4 0.5 1.6e-15 57.2 0.5 1.7 1 0 0 1 1 1 1 PAS fold Response_reg PF00072.24 RKP03603.1 - 5.6e-14 52.3 0.6 3.9e-10 39.9 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain PAS_9 PF13426.7 RKP03603.1 - 2.7e-09 37.2 0.0 2.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 RKP03603.1 - 3.3e-05 24.1 2.5 0.00047 20.4 0.6 3.1 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 RKP03603.1 - 0.00032 20.5 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 RKP03603.1 - 0.0025 17.8 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold UPRTase PF14681.6 RKP03604.1 - 1.1e-65 220.9 0.1 1.9e-65 220.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 RKP03604.1 - 6.6e-56 189.2 0.0 9.8e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 RKP03604.1 - 6.1e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 RKP03604.1 - 0.00034 21.2 0.0 0.00061 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 RKP03604.1 - 0.00061 19.5 0.0 0.26 11.0 0.0 3.1 3 0 0 3 3 3 2 Dephospho-CoA kinase AAA_17 PF13207.6 RKP03604.1 - 0.0019 18.6 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 RKP03604.1 - 0.0041 17.3 0.0 0.014 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RKP03604.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 RKP03604.1 - 0.09 12.5 0.1 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase Rer1 PF03248.13 RKP03606.1 - 6e-75 250.7 3.7 6.8e-75 250.5 3.7 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 RKP03606.1 - 0.037 13.6 0.4 0.037 13.6 0.4 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF4131 PF13567.6 RKP03606.1 - 0.067 12.8 7.0 1.6 8.3 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ThiF PF00899.21 RKP03607.1 - 2.6e-41 141.6 0.2 3.7e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 RKP03607.1 - 0.00018 21.8 2.7 0.00073 19.8 2.5 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 RKP03607.1 - 0.0014 18.0 0.3 0.0022 17.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 RKP03607.1 - 0.011 15.9 0.5 0.034 14.4 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain GST_N_2 PF13409.6 RKP03607.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ApbA PF02558.16 RKP03607.1 - 0.025 14.2 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 RKP03607.1 - 0.026 14.6 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RKP03607.1 - 0.035 13.4 0.5 0.055 12.8 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 RKP03607.1 - 0.054 13.1 0.2 0.095 12.3 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 RKP03607.1 - 0.057 13.0 0.4 0.095 12.3 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 RKP03607.1 - 0.064 13.3 0.2 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AA_kinase PF00696.28 RKP03607.1 - 0.096 12.3 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Amino acid kinase family 3HCDH_N PF02737.18 RKP03607.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 RKP03607.1 - 0.19 10.8 0.5 0.26 10.3 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A EF-hand_7 PF13499.6 RKP03608.1 - 3.9e-09 36.8 1.2 0.12 12.8 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 RKP03608.1 - 2.3e-07 30.2 0.9 0.089 12.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RKP03608.1 - 0.00014 21.2 0.0 0.75 9.5 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_13 PF17958.1 RKP03608.1 - 0.028 14.2 0.1 0.68 9.8 0.1 3.1 3 1 1 4 4 4 0 EF-hand domain EF-hand_5 PF13202.6 RKP03608.1 - 0.098 12.2 0.0 0.73 9.4 0.0 2.5 3 0 0 3 3 3 0 EF hand Ldh_1_N PF00056.23 RKP03609.1 - 9.2e-45 152.2 0.1 1.5e-44 151.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 RKP03609.1 - 3.8e-39 134.3 0.0 7.1e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ArfGap PF01412.18 RKP03610.1 - 3.1e-25 88.5 0.1 3.3e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf cwf18 PF08315.12 RKP03611.1 - 8.4e-12 45.9 10.8 2.2e-11 44.6 10.8 1.6 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor AKAP2_C PF15304.6 RKP03611.1 - 0.19 11.0 6.0 0.22 10.8 6.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus IF-2B PF01008.17 RKP03612.1 - 5.4e-63 212.8 0.0 6.2e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GATase_6 PF13522.6 RKP03613.1 - 1.2e-14 54.6 0.0 3.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RKP03613.1 - 1.4e-11 44.3 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 RKP03613.1 - 7.8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 RKP03613.1 - 0.0057 15.6 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II WD40 PF00400.32 RKP03614.1 - 5.8e-20 71.3 13.3 0.0032 18.3 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03614.1 - 9e-08 32.3 5.5 0.027 14.7 0.3 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 RKP03614.1 - 0.0018 18.5 1.0 19 5.7 0.1 4.8 5 0 0 5 5 5 1 Kelch motif IKI3 PF04762.12 RKP03614.1 - 0.0033 15.5 0.2 0.1 10.5 0.0 2.0 2 0 0 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 RKP03614.1 - 0.0037 16.3 0.1 0.25 10.3 0.0 3.0 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein VCBS PF13517.6 RKP03614.1 - 0.094 13.3 0.3 65 4.2 0.0 3.6 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glucosamine_iso PF01182.20 RKP03616.1 - 3.3e-63 213.6 0.0 3.8e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF459 PF04311.13 RKP03616.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Bap31_Bap29_C PF18035.1 RKP03616.1 - 0.042 13.8 0.1 0.074 13.1 0.1 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ribosomal_L18A PF01775.17 RKP03617.1 - 5.4e-53 178.2 0.6 6.6e-53 177.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PSP1 PF04468.12 RKP03618.1 - 9.3e-34 115.6 3.2 1.5e-33 114.9 3.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Methyltransf_5 PF01795.19 RKP03619.1 - 1.1e-58 199.2 0.0 3e-28 99.2 0.0 3.6 3 1 0 3 3 3 3 MraW methylase family Methyltransf_25 PF13649.6 RKP03619.1 - 0.084 13.6 0.0 0.33 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain APG6_N PF17675.1 RKP03620.1 - 0.19 12.2 15.3 2.5 8.6 4.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 RKP03620.1 - 1.4 9.4 10.3 0.65 10.4 1.3 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FlgN PF05130.12 RKP03620.1 - 2.2 8.8 8.4 5.9 7.4 7.9 2.1 1 1 0 1 1 1 0 FlgN protein V-ATPase_G PF03179.15 RKP03621.1 - 3e-23 82.4 14.9 3.7e-23 82.1 14.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit NIF PF03031.18 RKP03621.1 - 0.0077 16.0 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PE PF00934.20 RKP03621.1 - 0.013 15.8 4.2 0.024 15.0 4.2 1.3 1 0 0 1 1 1 0 PE family SKI PF01202.22 RKP03622.1 - 5.6e-07 29.8 0.0 1.3e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 RKP03622.1 - 3.7e-06 27.1 0.0 7.3e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP03622.1 - 1.6e-05 25.5 0.0 9.8e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKP03622.1 - 3.1e-05 24.3 0.0 4.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 RKP03622.1 - 0.00082 19.3 0.0 0.0019 18.1 0.0 1.8 1 1 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.27 RKP03622.1 - 0.002 18.6 0.0 0.0024 18.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RKP03622.1 - 0.01 16.2 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 RKP03622.1 - 0.012 15.9 0.1 0.036 14.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 RKP03622.1 - 0.042 13.4 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_14 PF13173.6 RKP03622.1 - 0.043 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKP03622.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 RKP03622.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 RKP03622.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 RKP03622.1 - 0.14 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PRK PF00485.18 RKP03622.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.17 RKP03622.1 - 0.17 11.5 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Ribosomal_L3 PF00297.22 RKP03623.1 - 6.9e-177 588.0 9.1 7.9e-177 587.8 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 tRNA-synt_2d PF01409.20 RKP03624.1 - 9.7e-47 159.5 0.4 1.9e-24 86.5 0.1 2.8 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 RKP03624.1 - 4.3e-22 78.3 0.0 8.5e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Exonuc_X-T_C PF08411.10 RKP03624.1 - 0.23 10.5 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Exonuclease C-terminal GrpE PF01025.19 RKP03625.1 - 3.7e-50 169.8 0.2 4.7e-50 169.5 0.2 1.1 1 0 0 1 1 1 1 GrpE DUF4407 PF14362.6 RKP03625.1 - 0.032 13.6 2.9 0.042 13.2 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp PF00026.23 RKP03626.1 - 3.3e-54 184.4 0.0 4.9e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKP03626.1 - 5.7e-06 26.7 0.0 0.032 14.5 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RKP03626.1 - 0.00067 20.2 0.2 0.082 13.6 0.0 3.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 RKP03626.1 - 0.019 14.7 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PRP38 PF03371.15 RKP03627.1 - 7.3e-46 156.2 0.0 8.2e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 PRP38 family LRR_9 PF14580.6 RKP03628.1 - 8.4e-17 61.2 2.8 1.3e-16 60.6 2.8 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RKP03628.1 - 6.4e-09 35.9 10.8 0.11 12.9 0.1 4.0 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKP03628.1 - 1.6e-05 24.6 9.7 0.00017 21.3 3.6 3.7 2 1 3 5 5 5 3 Leucine rich repeat Alpha_GJ PF03229.13 RKP03628.1 - 0.9 10.1 4.4 1.4 9.5 4.4 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J LRR_6 PF13516.6 RKP03628.1 - 2.3 8.5 3.8 68 3.9 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat GCV_T PF01571.21 RKP03629.1 - 4.6e-83 278.5 0.8 5.6e-83 278.2 0.8 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 RKP03629.1 - 1.2e-19 70.0 0.1 3.6e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 RKP03629.1 - 0.006 16.8 0.4 0.037 14.2 0.0 2.2 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family SEEEED PF14797.6 RKP03630.1 - 0.25 11.5 7.6 0.49 10.6 7.6 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Cwf_Cwc_15 PF04889.12 RKP03630.1 - 0.78 9.4 3.2 1.5 8.5 3.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DHHC PF01529.20 RKP03631.1 - 1.8e-39 134.9 0.9 2.1e-38 131.4 0.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ni_hydr_CYTB PF01292.20 RKP03631.1 - 0.0018 17.9 1.3 0.0018 17.9 1.3 2.2 2 0 0 2 2 2 2 Prokaryotic cytochrome b561 PTN13_u3 PF16599.5 RKP03632.1 - 0.034 14.2 0.4 0.063 13.3 0.4 1.3 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ Peptidase_S24 PF00717.23 RKP03633.1 - 2.8e-09 36.8 0.0 5.3e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Serglycin PF04360.12 RKP03634.1 - 0.013 15.4 0.7 0.013 15.4 0.7 2.3 2 0 0 2 2 2 0 Serglycin Chorismate_bind PF00425.18 RKP03635.1 - 8.3e-100 333.6 0.0 2.6e-99 332.0 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 RKP03635.1 - 7.7e-32 110.4 0.7 1.4e-26 93.4 0.1 3.9 2 2 0 2 2 2 2 Anthranilate synthase component I, N terminal region PDH PF02153.17 RKP03635.1 - 0.12 11.3 0.0 0.3 10.0 0.1 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase PseudoU_synth_1 PF01416.20 RKP03636.1 - 2.3e-22 79.5 0.0 4.6e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DEAD PF00270.29 RKP03637.1 - 2.7e-43 147.8 0.0 4.4e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP03637.1 - 9.7e-29 100.0 0.0 2.6e-28 98.6 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP03637.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Pyr_redox_2 PF07992.14 RKP03639.1 - 3.7e-10 39.5 0.0 1.1e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RKP03639.1 - 1.4e-06 28.4 0.0 3.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 RKP03639.1 - 2.3e-05 24.5 0.1 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 RKP03639.1 - 2.8e-05 23.5 0.2 0.0036 16.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 RKP03639.1 - 0.0025 18.3 0.0 1.6 9.3 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKP03639.1 - 0.0028 17.0 0.1 0.3 10.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 RKP03639.1 - 0.023 13.6 0.0 0.049 12.5 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 RKP03639.1 - 0.024 13.3 0.0 0.047 12.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 RKP03639.1 - 0.036 13.3 0.3 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Dpy-30 PF05186.13 RKP03640.1 - 0.0023 17.6 0.1 0.005 16.5 0.1 1.6 1 1 0 1 1 1 1 Dpy-30 motif HALZ PF02183.18 RKP03640.1 - 0.019 15.1 1.8 0.04 14.1 1.8 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 RKP03640.1 - 0.037 14.2 2.1 0.038 14.2 0.2 2.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 BMFP PF04380.13 RKP03640.1 - 0.068 13.7 3.3 0.22 12.0 3.5 1.7 2 0 0 2 2 2 0 Membrane fusogenic activity WD40_alt PF14077.6 RKP03640.1 - 0.074 12.9 0.8 0.5 10.3 0.8 2.2 1 1 0 1 1 1 0 Alternative WD40 repeat motif Seadorna_VP6 PF07407.11 RKP03640.1 - 0.1 11.5 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF2315 PF10231.9 RKP03641.1 - 5.9e-08 32.8 0.0 2.7e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Apoptogenic protein 1 KCNQC3-Ank-G_bd PF11956.8 RKP03641.1 - 0.03 14.6 0.5 0.085 13.1 0.5 1.8 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 MutS_V PF00488.21 RKP03643.1 - 8.4e-56 189.0 0.0 2e-55 187.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKP03643.1 - 4.3e-24 85.8 2.3 1e-23 84.6 2.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 RKP03643.1 - 6.5e-12 45.9 0.1 2.1e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 RKP03643.1 - 1.6e-08 34.8 0.2 2.8e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 RKP03643.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 RKP03643.1 - 0.084 12.5 0.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RKP03643.1 - 0.13 12.8 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain JAB PF01398.21 RKP03644.1 - 1.8e-07 31.1 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Nic96 PF04097.14 RKP03645.1 - 1.8e-88 297.6 0.0 2.5e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_7 PF13176.6 RKP03645.1 - 0.12 12.5 0.1 36 4.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4542 PF15075.6 RKP03645.1 - 0.2 12.0 0.0 21 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Methyltransf_16 PF10294.9 RKP03646.1 - 1.7e-11 44.2 0.1 3.7e-11 43.1 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_12 PF08242.12 RKP03646.1 - 0.0019 18.9 0.0 0.0038 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP03646.1 - 0.095 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RKP03646.1 - 0.25 11.1 0.1 0.39 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_23 PF13476.6 RKP03647.1 - 8.7e-15 55.8 0.0 1.4e-14 55.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 RKP03647.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RKP03647.1 - 9.1e-06 25.6 0.8 4.1e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 RKP03647.1 - 0.0011 17.8 0.8 0.67 8.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RKP03647.1 - 0.0026 17.5 0.0 0.0066 16.2 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Atg14 PF10186.9 RKP03647.1 - 0.019 14.1 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_27 PF13514.6 RKP03647.1 - 0.03 13.9 0.5 0.18 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RKP03647.1 - 0.038 13.3 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RKP03647.1 - 0.058 13.9 2.1 1.2 9.7 0.8 2.4 2 1 0 2 2 2 0 ABC transporter ABC_tran_Xtn PF12848.7 RKP03647.1 - 0.087 12.9 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 ABC transporter DivIC PF04977.15 RKP03647.1 - 0.097 12.5 0.7 0.2 11.5 0.4 1.7 1 1 0 1 1 1 0 Septum formation initiator AAA_21 PF13304.6 RKP03647.1 - 0.56 10.0 4.8 0.48 10.2 2.6 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Proteasome PF00227.26 RKP03648.1 - 3.3e-58 196.3 0.0 4.6e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKP03648.1 - 1.1e-09 37.8 0.3 3.6e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HMG_box PF00505.19 RKP03649.1 - 3.2e-16 59.5 0.1 5.8e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKP03649.1 - 1.5e-08 35.1 0.1 3.1e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Ank_4 PF13637.6 RKP03650.1 - 1.9e-07 31.5 0.1 0.22 12.1 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKP03650.1 - 5.5e-06 26.9 0.0 0.066 13.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKP03650.1 - 0.0003 21.0 0.6 37 5.4 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 RKP03650.1 - 0.0034 17.7 0.2 18 5.8 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeats (many copies) DUF4832 PF16116.5 RKP03651.1 - 0.015 15.2 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) DUF4874 PF16173.5 RKP03651.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Mito_carr PF00153.27 RKP03652.1 - 2.1e-51 171.8 2.2 6.7e-19 67.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 RKP03652.1 - 0.054 13.6 0.1 2.7 8.2 0.1 2.6 2 0 0 2 2 2 0 PrcB C-terminal Fungal_trans PF04082.18 RKP03653.1 - 2.1e-11 43.4 0.0 4.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 RKP03653.1 - 1.1e-05 25.4 6.4 1.8e-05 24.8 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PT-TG PF14449.6 RKP03653.1 - 0.14 12.1 0.0 0.52 10.2 0.0 2.0 1 0 0 1 1 1 0 Pre-toxin TG SRP19 PF01922.17 RKP03655.1 - 1.4e-19 70.8 0.0 2.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Regnase_1_C PF18561.1 RKP03655.1 - 0.16 11.7 0.7 0.5 10.2 0.7 1.8 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Nup54 PF13874.6 RKP03656.1 - 5.7e-31 107.5 3.2 5.7e-31 107.5 3.2 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF2722 PF10846.8 RKP03656.1 - 4.7e-05 22.5 7.7 6.2e-05 22.1 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Nucleoporin_FG PF13634.6 RKP03656.1 - 0.018 15.8 38.2 13 6.7 38.2 2.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region Suf PF05843.14 RKP03656.1 - 0.072 13.1 6.3 0.13 12.2 6.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 RKP03656.1 - 0.11 12.1 21.8 0.17 11.4 21.8 1.2 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 RKP03656.1 - 0.18 11.6 17.2 1.4 8.7 9.9 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF4770 PF15994.5 RKP03656.1 - 0.32 11.2 6.4 0.64 10.2 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Presenilin PF01080.17 RKP03656.1 - 0.44 9.3 0.9 0.54 9.0 0.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 RKP03656.1 - 5.6 6.2 11.9 0.43 9.9 1.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 RKP03656.1 - 9.9 6.0 25.6 13 5.6 25.2 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PXA PF02194.15 RKP03657.1 - 1.3e-34 119.8 0.0 1.3e-34 119.8 0.0 2.4 2 0 0 2 2 1 1 PXA domain SRF-TF PF00319.18 RKP03657.1 - 6e-23 80.1 0.1 9.8e-23 79.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Nexin_C PF08628.12 RKP03657.1 - 6.5e-06 26.7 0.1 0.0012 19.4 0.0 3.2 2 1 0 2 2 1 1 Sorting nexin C terminal DDHD PF02862.17 RKP03657.1 - 0.22 11.7 10.8 0.18 11.9 7.9 2.1 2 0 0 2 2 2 0 DDHD domain eIF-3_zeta PF05091.12 RKP03657.1 - 0.25 10.3 26.1 0.38 9.7 26.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Plasmodium_Vir PF05795.11 RKP03657.1 - 0.52 9.7 11.6 0.85 9.0 6.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein BNIP2 PF12496.8 RKP03657.1 - 0.61 10.5 7.6 1.3 9.4 7.6 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ALMT PF11744.8 RKP03657.1 - 1.3 7.8 9.1 2.2 7.0 9.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Tim54 PF11711.8 RKP03657.1 - 1.5 7.6 14.8 2.4 6.9 14.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EMC3_TMCO1 PF01956.16 RKP03657.1 - 1.9 8.2 10.8 3.7 7.3 10.8 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PAT1 PF09770.9 RKP03657.1 - 4.4 5.4 36.1 8 4.6 36.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.11 RKP03657.1 - 5.3 5.4 19.1 8.1 4.8 19.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.11 RKP03657.1 - 5.3 6.3 28.9 9.5 5.5 28.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SHMT PF00464.19 RKP03658.1 - 4.2e-192 638.1 0.0 4.9e-192 637.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF4142 PF13628.6 RKP03658.1 - 0.14 12.4 3.8 8.3 6.7 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) CBM_48 PF02922.18 RKP03660.1 - 6.6e-19 68.1 0.0 2.4e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 RKP03660.1 - 1.2e-15 58.0 0.1 4.3e-09 36.4 0.1 2.8 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Ribosomal_L11_N PF03946.14 RKP03662.1 - 7.7e-21 73.7 0.4 1.1e-20 73.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 RKP03662.1 - 3.5e-14 53.1 0.1 8.2e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IL7 PF01415.16 RKP03662.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin 7/9 family MFS_1 PF07690.16 RKP03663.1 - 1.7e-37 129.2 32.7 2.2e-37 128.8 32.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RKP03663.1 - 0.00048 19.1 4.4 0.00048 19.1 4.4 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 RKP03663.1 - 0.0016 17.8 25.2 0.0054 16.1 1.0 2.1 1 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 RKP03663.1 - 0.0016 16.9 0.8 0.003 16.1 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 RKP03663.1 - 0.0047 15.8 11.1 0.23 10.3 0.1 2.4 2 1 0 2 2 2 2 MFS_1 like family Lactamase_B_2 PF12706.7 RKP03664.1 - 9.5e-38 129.7 0.5 1.2e-37 129.4 0.5 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RKP03664.1 - 1.6e-17 63.9 0.0 2.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Thioredoxin PF00085.20 RKP03665.1 - 6.2e-44 148.2 0.0 7.5e-24 83.7 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 RKP03665.1 - 3.8e-11 43.7 0.0 6.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 RKP03665.1 - 1.1e-10 42.0 0.0 4.4e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 RKP03665.1 - 1.1e-09 38.3 0.0 8.3e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 RKP03665.1 - 9.4e-09 35.0 0.0 0.00074 19.0 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 RKP03665.1 - 1e-06 28.9 0.0 0.012 15.9 0.0 2.8 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 RKP03665.1 - 3e-06 27.1 0.0 0.0063 16.4 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 RKP03665.1 - 3.1e-06 27.0 0.0 0.0083 15.8 0.0 2.2 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 RKP03665.1 - 0.00066 19.9 0.1 0.23 11.7 0.0 2.6 2 1 0 2 2 2 1 Glutaredoxin TraF PF13728.6 RKP03665.1 - 0.014 15.3 0.0 0.61 9.9 0.0 2.4 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 RKP03665.1 - 0.028 14.2 0.2 0.99 9.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin F-box-like PF12937.7 RKP03666.1 - 3.5e-05 23.6 0.5 8.6e-05 22.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RKP03666.1 - 0.0062 16.4 1.0 0.012 15.5 1.0 1.4 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 RKP03666.1 - 0.49 10.4 7.6 4.9 7.3 0.5 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Abhydrolase_1 PF00561.20 RKP03668.1 - 6.6e-26 91.5 0.5 5.1e-25 88.6 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RKP03668.1 - 1.2e-20 75.0 8.9 1.5e-20 74.8 8.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RKP03668.1 - 3.1e-13 49.6 0.8 5.4e-13 48.8 0.8 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 RKP03668.1 - 3.6e-07 30.5 0.0 4.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 RKP03668.1 - 1.1e-06 28.6 0.2 0.0047 16.7 0.2 2.2 1 1 0 2 2 2 2 PGAP1-like protein Palm_thioest PF02089.15 RKP03668.1 - 6.2e-05 23.0 0.0 7.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 RKP03668.1 - 0.0011 18.7 0.3 0.0023 17.6 0.1 1.6 2 0 0 2 2 2 1 Putative esterase DUF676 PF05057.14 RKP03668.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.11 RKP03668.1 - 0.0066 15.5 0.1 0.0097 14.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase DUF915 PF06028.11 RKP03668.1 - 0.016 14.6 0.1 0.3 10.4 0.1 2.4 2 1 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 RKP03668.1 - 0.02 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 RKP03668.1 - 0.041 12.6 0.0 0.1 11.3 0.0 1.7 1 1 0 1 1 1 0 Ndr family Peptidase_C48 PF02902.19 RKP03669.1 - 4.4e-35 121.5 0.0 6.4e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NMD3 PF04981.13 RKP03669.1 - 0.0014 18.2 0.2 0.0023 17.4 0.2 1.2 1 0 0 1 1 1 1 NMD3 family ATG_C PF09333.11 RKP03669.1 - 0.3 11.5 2.2 1.4 9.3 2.2 2.2 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain LZ3wCH PF18517.1 RKP03670.1 - 9.4e-09 35.2 0.4 2.5e-08 33.9 0.4 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Type2_restr_D3 PF16902.5 RKP03670.1 - 0.075 13.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain bZIP_1 PF00170.21 RKP03670.1 - 0.3 11.2 3.1 23 5.1 1.2 3.0 1 1 2 3 3 3 0 bZIP transcription factor ADIP PF11559.8 RKP03672.1 - 0.0063 16.6 0.8 0.0063 16.6 0.8 1.8 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 RKP03672.1 - 0.12 12.4 4.9 0.23 11.5 4.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 RKP03672.1 - 0.88 10.0 6.2 0.67 10.4 4.1 1.7 2 0 0 2 2 2 0 Fez1 Pkinase PF00069.25 RKP03673.1 - 3.9e-65 219.8 0.0 4.4e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03673.1 - 1.2e-45 155.8 0.0 1.5e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP03673.1 - 1.4e-08 33.9 0.0 1.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKP03673.1 - 2.6e-08 33.5 0.0 8.4e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKP03673.1 - 2.6e-05 23.4 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RKP03673.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RKP03673.1 - 0.054 13.4 0.0 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIS_M PF07500.14 RKP03674.1 - 5e-25 88.2 4.2 5e-25 88.2 4.2 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 RKP03674.1 - 1.7e-19 69.4 6.8 2.8e-19 68.7 6.8 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 RKP03674.1 - 4e-10 39.5 1.2 6.6e-10 38.9 0.3 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RPA_interact_N PF14766.6 RKP03674.1 - 0.064 12.9 2.6 1.2 8.8 0.0 3.2 3 0 0 3 3 3 0 Replication protein A interacting N-terminal zf-DNL PF05180.12 RKP03674.1 - 0.12 12.3 2.0 0.24 11.4 2.0 1.4 1 0 0 1 1 1 0 DNL zinc finger RNase_PH_C PF03725.15 RKP03675.1 - 8.2e-13 48.2 0.0 4.1e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 RKP03675.1 - 7.3e-12 45.9 0.0 1.4e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ERO1 PF04137.15 RKP03676.1 - 3e-117 391.8 0.0 3.7e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) NTP_transferase PF00483.23 RKP03677.1 - 3.6e-47 161.0 0.0 4.7e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKP03677.1 - 7.4e-12 45.9 0.0 1.3e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 RKP03677.1 - 1.6e-10 40.3 6.1 3.7e-07 29.6 0.4 4.2 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 RKP03677.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 RKP03677.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Hexapep_2 PF14602.6 RKP03677.1 - 1.5 8.6 5.4 1.2 9.0 0.1 3.2 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase SNO PF01174.19 RKP03678.1 - 6e-49 166.5 0.0 6.9e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 RKP03678.1 - 7.1e-09 35.5 0.0 8.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 RKP03678.1 - 3.6e-06 26.8 0.0 5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 RKP03678.1 - 0.00087 19.1 0.0 0.0029 17.4 0.0 1.7 1 1 1 2 2 2 1 DJ-1/PfpI family OpgC_C PF10129.9 RKP03679.1 - 0.0049 15.8 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 OpgC protein SR-25 PF10500.9 RKP03679.1 - 4.2 6.9 12.1 10 5.7 12.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SDA1 PF05285.12 RKP03680.1 - 0.00025 20.6 11.2 0.00047 19.7 11.2 1.3 1 0 0 1 1 1 1 SDA1 Abhydrolase_1 PF00561.20 RKP03680.1 - 0.021 14.5 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold RNA12 PF10443.9 RKP03681.1 - 6.9e-94 315.1 0.0 1.9e-58 198.3 0.0 2.1 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 RKP03681.1 - 9.7e-08 32.2 0.0 1.2e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 RKP03681.1 - 5.4e-06 26.1 0.0 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 RKP03681.1 - 0.0013 19.1 0.0 0.0042 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RKP03681.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RKP03681.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAGAT PF03982.13 RKP03682.1 - 3.8e-100 334.6 0.0 4.7e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CotJB PF12652.7 RKP03682.1 - 0.034 14.3 0.5 0.034 14.3 0.5 2.1 3 0 0 3 3 3 0 CotJB protein CH PF00307.31 RKP03686.1 - 6.4e-31 106.8 0.0 2.4e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain RsfS PF02410.15 RKP03687.1 - 3.8e-18 65.7 0.1 9.6e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Tetraspanin PF00335.20 RKP03689.1 - 0.021 14.5 0.1 0.035 13.8 0.1 1.4 1 1 0 1 1 1 0 Tetraspanin family Zip PF02535.22 RKP03689.1 - 0.065 12.5 5.2 2.3 7.3 5.8 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Frag1 PF10277.9 RKP03689.1 - 1.2 8.6 5.5 0.13 11.8 1.3 1.4 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family SUR7 PF06687.12 RKP03689.1 - 1.5 8.4 5.6 7.2 6.2 5.8 1.7 1 1 0 1 1 1 0 SUR7/PalI family Methyltransf_23 PF13489.6 RKP03690.1 - 3.5e-05 23.7 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP03690.1 - 0.00099 19.8 0.0 0.0042 17.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKP03690.1 - 0.0039 17.0 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKP03690.1 - 0.0047 17.6 0.1 0.072 13.8 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKP03690.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 RKP03690.1 - 0.034 14.8 0.0 0.53 11.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Prenyltrans PF00432.21 RKP03691.1 - 1.6e-15 56.5 1.6 9e-06 25.3 0.0 5.5 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat RICTOR_N PF14664.6 RKP03691.1 - 0.25 10.3 0.0 0.35 9.8 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term ALS_ss_C PF10369.9 RKP03693.1 - 5.3e-20 71.4 0.0 1.3e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.25 RKP03693.1 - 3.5e-13 49.1 0.1 6.3e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 RKP03693.1 - 8e-09 35.2 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 ACT domain LytR_C PF13399.6 RKP03693.1 - 0.018 16.0 0.2 0.078 14.0 0.0 2.0 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator ACT_7 PF13840.6 RKP03693.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 ACT domain Ribosomal_60s PF00428.19 RKP03693.1 - 1.9 9.1 5.8 17 6.1 1.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein IlvN PF07991.12 RKP03695.1 - 7.4e-44 149.2 0.1 1.3e-43 148.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 RKP03695.1 - 1.8e-40 138.6 0.0 3.1e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain G_glu_transpept PF01019.21 RKP03696.1 - 5.6e-151 503.8 0.0 6.4e-151 503.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PHP PF02811.19 RKP03697.1 - 2.6e-08 34.3 0.0 4.2e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 PHP domain COX4 PF02936.14 RKP03698.1 - 9.2e-24 84.0 0.1 1.1e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF4720 PF15846.5 RKP03698.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) SAM_2 PF07647.17 RKP03699.1 - 1.3e-06 28.4 0.0 3.3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RKP03699.1 - 0.0021 18.5 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) VWA PF00092.28 RKP03699.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Gryzun PF07919.12 RKP03700.1 - 1.6e-07 30.5 0.6 2.5e-07 29.9 0.6 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 RKP03700.1 - 0.0046 16.6 15.4 0.089 12.4 2.5 3.5 4 0 0 4 4 4 2 Foie gras liver health family 1 TRAPPC10 PF12584.8 RKP03700.1 - 0.071 12.8 0.1 0.45 10.2 0.0 2.1 2 1 0 3 3 3 0 Trafficking protein particle complex subunit 10, TRAPPC10 MscS_porin PF12795.7 RKP03701.1 - 0.003 17.2 4.5 0.003 17.2 4.5 1.6 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain Filament PF00038.21 RKP03701.1 - 0.013 15.1 5.3 0.021 14.5 5.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein BRE1 PF08647.11 RKP03701.1 - 0.023 14.8 2.2 0.045 13.8 1.7 1.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 RKP03701.1 - 0.028 14.5 5.2 0.043 13.9 5.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2383 PF09537.10 RKP03701.1 - 0.076 13.4 1.1 0.44 10.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) CEP209_CC5 PF16574.5 RKP03701.1 - 0.085 13.0 2.0 0.091 12.9 0.4 1.8 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 HMMR_N PF15905.5 RKP03701.1 - 0.11 12.0 4.5 0.17 11.3 4.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ABC_tran_CTD PF16326.5 RKP03701.1 - 0.17 12.1 0.8 0.37 11.1 0.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Sec20 PF03908.13 RKP03701.1 - 0.22 11.5 0.8 0.5 10.3 0.8 1.6 1 0 0 1 1 1 0 Sec20 Syntaxin_2 PF14523.6 RKP03701.1 - 0.27 11.6 1.8 0.54 10.6 1.8 1.4 1 0 0 1 1 1 0 Syntaxin-like protein Fib_alpha PF08702.10 RKP03701.1 - 0.92 9.7 3.3 0.89 9.7 0.3 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 RKP03701.1 - 3.9 8.2 11.1 1.1 9.9 2.8 2.9 1 1 1 2 2 2 0 SlyX Pex16 PF08610.10 RKP03702.1 - 7.9e-74 248.7 0.0 9.2e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) PLRV_ORF5 PF01690.17 RKP03703.1 - 0.37 9.5 2.1 0.65 8.6 2.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Cas1_AcylT PF07779.12 RKP03704.1 - 1.1e-101 341.1 17.3 1.4e-101 340.7 17.3 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Abhydrolase_6 PF12697.7 RKP03705.1 - 1.1e-09 39.2 4.1 1.1e-09 39.2 4.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 RKP03705.1 - 0.03 14.0 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 RKP03705.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Rod_C PF10493.9 RKP03706.1 - 1e-26 93.5 0.5 2.2e-26 92.4 0.5 1.5 1 0 0 1 1 1 1 Rough deal protein C-terminal region S8_pro-domain PF16470.5 RKP03706.1 - 3.5 8.5 4.8 5.7 7.8 1.3 2.6 2 0 0 2 2 2 0 Peptidase S8 pro-domain NigD_N PF12667.7 RKP03707.1 - 0.0038 17.3 0.2 1.6 8.9 0.5 2.6 2 0 0 2 2 2 2 NigD-like N-terminal OB domain TPR_19 PF14559.6 RKP03709.1 - 1.3e-07 32.0 8.1 0.00014 22.3 0.3 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKP03709.1 - 5e-05 23.4 4.8 0.0013 18.8 2.3 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03709.1 - 6.4e-05 22.8 2.1 2.7 8.3 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03709.1 - 8.8e-05 22.4 1.4 3.9 7.9 0.0 5.5 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RKP03709.1 - 0.0001 21.8 4.7 0.00021 20.8 4.7 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 RKP03709.1 - 0.0027 17.9 0.7 15 6.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 RKP03709.1 - 0.0082 16.9 9.2 0.44 11.5 0.2 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKP03709.1 - 0.0085 16.7 0.3 0.0085 16.7 0.3 3.5 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03709.1 - 0.016 15.8 1.1 44 5.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKP03709.1 - 0.018 15.3 1.0 12 6.3 0.3 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RKP03709.1 - 0.041 13.9 4.3 2.7 8.2 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKP03709.1 - 0.046 14.0 10.7 0.25 11.7 1.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKP03709.1 - 0.13 12.2 0.7 10 6.2 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKP03709.1 - 0.18 12.5 10.0 0.65 10.8 1.5 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 RKP03711.1 - 3.2e-12 46.5 0.1 5e-11 42.7 0.1 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 RKP03711.1 - 0.0035 17.3 1.9 0.0035 17.3 1.9 1.7 2 0 0 2 2 2 1 Zinc-finger VPS11_C PF12451.8 RKP03711.1 - 0.018 15.3 0.1 0.047 13.9 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal TPR_11 PF13414.6 RKP03711.1 - 0.17 11.6 0.6 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 TPR repeat zf-rbx1 PF12678.7 RKP03711.1 - 0.24 11.7 0.4 0.64 10.4 0.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKP03711.1 - 3.6 7.6 4.3 13 5.8 4.3 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 RKP03711.1 - 3.7 8.0 5.4 0.52 10.7 0.6 2.0 2 0 0 2 2 2 0 Ring finger domain NIF PF03031.18 RKP03712.1 - 2.8e-20 72.7 0.0 4.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acetyltransf_10 PF13673.7 RKP03713.1 - 9.8e-08 32.0 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKP03713.1 - 6.4e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKP03713.1 - 0.033 14.4 0.0 0.086 13.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family PHD PF00628.29 RKP03713.1 - 0.22 11.4 1.0 0.53 10.2 1.0 1.6 1 0 0 1 1 1 0 PHD-finger MAD PF05557.13 RKP03714.1 - 6.5e-36 124.0 23.8 2.2e-29 102.4 0.0 3.5 3 1 0 3 3 3 3 Mitotic checkpoint protein Fez1 PF06818.15 RKP03714.1 - 0.00091 19.7 0.8 0.00091 19.7 0.8 5.3 3 3 1 4 4 4 1 Fez1 AviRa PF11599.8 RKP03714.1 - 0.0032 16.9 1.3 0.0032 16.9 1.3 2.6 3 0 0 3 3 3 1 RRNA methyltransferase AviRa bZIP_1 PF00170.21 RKP03714.1 - 0.0037 17.3 1.3 0.0037 17.3 1.3 5.0 6 0 0 6 6 6 1 bZIP transcription factor Zip PF02535.22 RKP03714.1 - 0.11 11.7 0.2 0.35 10.0 0.2 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter GPHR_N PF12537.8 RKP03714.1 - 0.44 10.7 11.4 1.6 8.9 0.0 4.5 5 0 0 5 5 5 0 The Golgi pH Regulator (GPHR) Family N-terminal KRTAP PF11759.8 RKP03714.1 - 0.74 10.4 3.4 1.6 9.3 3.4 1.5 1 0 0 1 1 1 0 Keratin-associated matrix Herpes_IE68 PF02479.16 RKP03714.1 - 8 6.1 7.8 1 9.0 0.2 3.4 3 0 0 3 3 3 0 Herpesvirus immediate early protein WD40 PF00400.32 RKP03715.1 - 1.5e-38 130.1 15.8 5.6e-08 33.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03715.1 - 1.1e-05 25.6 0.4 0.74 10.1 0.1 4.6 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP03715.1 - 1.8e-05 23.6 3.6 0.22 10.2 0.0 3.8 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RKP03715.1 - 0.0041 15.9 0.0 13 4.4 0.0 3.8 1 1 3 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 RKP03715.1 - 0.0084 14.7 0.0 0.94 7.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 RKP03715.1 - 0.11 13.0 0.1 6.9 7.3 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain MOZ_SAS PF01853.18 RKP03716.1 - 2.3e-82 275.0 0.2 3e-82 274.6 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RKP03716.1 - 2.6e-20 71.8 2.2 5.4e-20 70.8 2.2 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 RKP03716.1 - 0.0023 18.3 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2314 PF10077.9 RKP03716.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) Acetyltransf_1 PF00583.25 RKP03716.1 - 0.13 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Asparaginase PF00710.20 RKP03717.1 - 1.1e-56 191.4 0.0 2.5e-56 190.2 0.0 1.6 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 RKP03717.1 - 4.5e-30 104.2 0.0 9.4e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 RKP03717.1 - 1.3e-12 48.1 0.2 3.4e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKP03717.1 - 2.5e-08 34.3 0.5 1.7e-07 31.6 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RKP03717.1 - 4.1e-08 33.3 2.2 4.4e-07 30.1 0.4 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 RKP03717.1 - 1.6e-06 28.3 0.6 1.4e-05 25.2 0.2 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKP03717.1 - 1.6e-06 28.0 0.3 1.9e-05 24.7 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat zf-DNL PF05180.12 RKP03717.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 DNL zinc finger Vps35 PF03635.17 RKP03718.1 - 5.3e-137 458.3 0.0 8.7e-64 216.3 0.0 6.4 6 1 0 6 6 6 5 Vacuolar protein sorting-associated protein 35 NifU_N PF01592.16 RKP03719.1 - 2.6e-48 163.4 0.1 3.6e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain UPF0020 PF01170.18 RKP03721.1 - 4.5e-08 33.0 0.1 0.0046 16.7 0.1 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 RKP03721.1 - 0.00058 19.6 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_15 PF09445.10 RKP03721.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Exo70 PF03081.15 RKP03722.1 - 2.5e-64 217.7 0.6 7e-62 209.6 0.0 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Sec34 PF04136.15 RKP03722.1 - 0.0023 17.9 0.6 0.0057 16.5 0.4 1.8 2 0 0 2 2 2 1 Sec34-like family Sec3_C PF09763.9 RKP03722.1 - 0.015 13.8 5.8 0.083 11.3 4.5 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec3 SSP160 PF06933.11 RKP03722.1 - 0.019 13.2 5.5 0.028 12.7 5.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4248 PF14053.6 RKP03722.1 - 0.1 12.7 0.4 24 5.0 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) RasGAP PF00616.19 RKP03723.1 - 1.1e-58 198.3 0.0 3.1e-58 196.9 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 RKP03723.1 - 9.9e-25 87.3 0.7 2.5e-24 86.0 0.7 1.7 1 0 0 1 1 1 1 RasGAP C-terminus Herpes_UL14 PF03580.14 RKP03723.1 - 0.023 14.9 0.6 0.096 12.9 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL14-like protein PMSR PF01625.21 RKP03723.1 - 0.039 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Sec5 PF15469.6 RKP03723.1 - 0.058 13.2 0.3 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 bZIP_1 PF00170.21 RKP03723.1 - 0.096 12.8 0.6 0.38 10.9 0.6 2.1 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 RKP03723.1 - 0.37 11.4 5.1 5.6 7.7 0.5 2.9 2 0 0 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 RKP03723.1 - 0.4 10.8 10.2 2.2 8.4 1.8 2.5 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 RKP03723.1 - 0.7 8.7 7.6 4.5 6.0 1.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 RKP03723.1 - 1.2 9.2 7.9 0.84 9.7 1.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 RKP03723.1 - 2.4 7.6 6.9 1 8.8 0.8 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal BRE1 PF08647.11 RKP03723.1 - 8.1 6.6 10.0 16 5.7 1.0 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase NAD_binding_5 PF07994.12 RKP03725.1 - 1.3e-117 392.8 0.0 3.6e-117 391.3 0.0 1.6 1 1 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 RKP03725.1 - 1.2e-39 134.9 0.0 2.1e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase TRAP_alpha PF03896.16 RKP03726.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_1 PF00076.22 RKP03728.1 - 7.1e-10 38.6 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03728.1 - 0.00069 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif NUC153 PF08159.12 RKP03729.1 - 2.7e-09 36.7 3.0 5.7e-09 35.6 3.0 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 RKP03729.1 - 0.002 18.4 0.0 0.018 15.4 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKP03729.1 - 0.013 16.4 0.0 1.6 9.7 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DSPc PF00782.20 RKP03730.1 - 0.00011 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKP03730.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pescadillo_N PF06732.11 RKP03731.1 - 5.7e-102 340.9 0.1 1.4e-101 339.7 0.1 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 RKP03731.1 - 4.6e-12 46.2 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RKP03731.1 - 0.00022 21.5 0.0 0.0015 18.9 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Mito_carr PF00153.27 RKP03732.1 - 1.4e-29 101.9 7.7 9.2e-19 67.2 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Iso_dh PF00180.20 RKP03733.1 - 3.1e-101 339.0 0.0 3.4e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-RING_2 PF13639.6 RKP03735.1 - 9.4e-13 48.3 4.2 1.4e-12 47.7 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKP03735.1 - 1e-09 38.0 4.2 1.6e-09 37.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKP03735.1 - 8.6e-09 35.0 1.4 1.5e-08 34.2 1.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 RKP03735.1 - 8.9e-09 35.5 2.3 1.8e-08 34.5 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 RKP03735.1 - 2.6e-07 30.4 3.2 3.9e-07 29.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP03735.1 - 1.6e-05 24.8 2.9 2.4e-05 24.2 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RKP03735.1 - 0.00011 22.0 2.9 0.00017 21.4 2.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKP03735.1 - 0.00024 20.9 2.0 0.0004 20.2 2.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 RKP03735.1 - 0.00076 19.5 0.8 0.0014 18.7 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 RKP03735.1 - 0.0048 17.0 4.1 0.0081 16.3 4.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.6 RKP03735.1 - 0.0065 16.5 3.5 0.012 15.6 3.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 RKP03735.1 - 0.01 15.4 3.2 0.017 14.8 3.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 RKP03735.1 - 0.13 12.1 4.1 0.22 11.5 4.1 1.3 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 RKP03735.1 - 0.15 12.2 4.0 0.37 11.0 4.0 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 RKP03735.1 - 1.2 9.0 4.4 2.1 8.2 4.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CLAMP PF14769.6 RKP03737.1 - 1.6e-20 73.4 0.5 2.9e-20 72.6 0.5 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 DUF3867 PF12983.7 RKP03737.1 - 0.04 14.0 0.3 0.085 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) DUF1359 PF07097.11 RKP03737.1 - 0.077 13.2 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) ECH_1 PF00378.20 RKP03739.1 - 1.3e-19 70.5 0.2 1.8e-19 70.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKP03739.1 - 3e-09 36.8 0.3 3.9e-09 36.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Flu_PA PF00603.17 RKP03739.1 - 0.015 13.5 0.0 0.019 13.1 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA MreC PF04085.14 RKP03739.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 rod shape-determining protein MreC WD40 PF00400.32 RKP03740.1 - 6.5e-61 200.9 22.7 1.8e-09 38.0 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03740.1 - 8.3e-24 83.7 0.0 0.0014 18.9 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKP03740.1 - 4.9e-12 46.1 0.0 4.5e-06 26.7 0.0 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RKP03740.1 - 2.3e-09 36.4 6.9 0.026 13.2 0.1 5.0 2 2 3 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 RKP03740.1 - 8.7e-07 28.6 0.0 0.0005 19.5 0.0 3.6 1 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 RKP03740.1 - 1.3e-06 27.6 1.0 0.032 13.2 0.0 4.3 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RKP03740.1 - 4.5e-06 25.3 0.0 0.0027 16.1 0.0 2.9 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 RKP03740.1 - 4.7e-05 22.5 0.0 0.57 9.1 0.0 3.4 1 1 3 4 4 4 3 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 RKP03740.1 - 0.0013 17.9 0.0 0.39 9.7 0.0 2.8 1 1 2 3 3 3 2 VID27 C-terminal WD40-like domain PD40 PF07676.12 RKP03740.1 - 0.0077 16.1 0.4 2.3 8.2 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 RKP03740.1 - 0.012 14.1 0.0 2.9 6.3 0.0 2.8 1 1 3 4 4 4 0 Cytochrome D1 heme domain Ribosomal_L21e PF01157.18 RKP03741.1 - 2.1e-46 155.9 4.5 3.3e-46 155.3 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e S4 PF01479.25 RKP03742.1 - 1.3e-12 47.2 0.9 1.3e-12 47.2 0.9 2.8 4 0 0 4 4 4 1 S4 domain SAM_2 PF07647.17 RKP03743.1 - 8e-15 54.7 0.0 1.9e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 RKP03743.1 - 2.8e-12 46.9 0.0 5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 RKP03743.1 - 3e-12 45.9 0.0 4.5e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 RKP03743.1 - 3.2e-09 36.5 0.2 0.00087 19.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 RKP03743.1 - 9.5e-09 35.8 0.0 1.6e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.17 RKP03743.1 - 4.3e-07 29.5 0.1 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 RKP03743.1 - 3.9e-05 23.8 0.2 0.0085 16.4 0.1 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain SAM_4 PF18017.1 RKP03743.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) P66_CC PF16563.5 RKP03743.1 - 0.067 12.8 1.8 0.12 12.0 1.8 1.4 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Allexi_40kDa PF05549.11 RKP03743.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein SH3_4 PF06347.13 RKP03743.1 - 0.39 10.6 2.5 0.71 9.7 0.1 2.9 2 0 0 2 2 2 0 Bacterial SH3 domain WD40 PF00400.32 RKP03744.1 - 2.4e-18 66.1 14.1 8e-05 23.3 0.2 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03744.1 - 6.6e-07 29.5 0.0 1.9 8.8 0.0 5.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP03744.1 - 0.0035 16.4 0.0 0.025 13.6 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyoxal_oxid_N PF07250.11 RKP03746.1 - 7.4e-28 97.4 0.0 2.8e-26 92.2 0.0 2.8 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 RKP03746.1 - 2.8e-20 72.4 0.3 6.7e-20 71.2 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Trefoil PF00088.18 RKP03746.1 - 5.1e-08 32.7 3.0 9.5e-08 31.8 3.0 1.5 1 0 0 1 1 1 1 Trefoil (P-type) domain Kelch_4 PF13418.6 RKP03746.1 - 0.0064 16.5 0.4 18 5.5 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 RKP03746.1 - 0.013 15.4 0.3 18 5.5 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Glyco_transf_5 PF08323.11 RKP03747.1 - 2.8e-14 53.4 0.0 5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.24 RKP03747.1 - 6.2e-14 52.3 0.0 6.3e-13 49.0 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 RKP03747.1 - 4.7e-06 26.3 0.0 8.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 RKP03747.1 - 0.0038 17.2 0.1 0.011 15.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ASFV_J13L PF05568.11 RKP03748.1 - 1.4 8.6 8.3 2.2 8.0 8.3 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein MutS_III PF05192.18 RKP03749.1 - 0.054 13.7 9.9 0.084 13.1 9.0 1.7 1 1 0 1 1 1 0 MutS domain III OmpH PF03938.14 RKP03749.1 - 0.064 13.6 0.2 0.064 13.6 0.2 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1515 PF07439.11 RKP03749.1 - 0.43 10.6 1.9 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Syntaxin PF00804.25 RKP03749.1 - 1.8 8.2 7.2 0.36 10.5 1.8 2.2 1 1 0 2 2 2 0 Syntaxin FadA PF09403.10 RKP03749.1 - 2.8 8.5 5.4 2.5 8.6 1.2 2.8 1 1 1 2 2 2 0 Adhesion protein FadA AAA_13 PF13166.6 RKP03749.1 - 2.8 6.5 6.0 1.8 7.1 3.5 1.8 1 1 0 1 1 1 0 AAA domain AIP3 PF03915.13 RKP03749.1 - 4.2 6.4 9.8 0.65 9.0 0.9 2.2 1 1 1 2 2 2 0 Actin interacting protein 3 R3H PF01424.22 RKP03750.1 - 1.4e-09 37.8 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 R3H domain PLDc_2 PF13091.6 RKP03751.1 - 7.3e-12 45.3 0.0 2.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 RKP03751.1 - 4.8e-06 26.5 0.0 0.033 14.4 0.0 2.6 2 1 0 2 2 2 2 Phospholipase D Active site motif HOOK PF05622.12 RKP03752.1 - 3.5e-38 131.3 54.6 4.2e-18 64.9 43.7 4.7 3 2 0 3 3 3 3 HOOK protein JIP_LZII PF16471.5 RKP03752.1 - 0.047 13.9 0.4 0.047 13.9 0.4 7.9 7 1 2 9 9 9 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 RKP03752.1 - 0.12 12.6 84.0 1.4 9.1 3.3 6.1 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 RKP03752.1 - 0.28 11.4 27.2 0.2 11.9 8.1 4.8 2 2 2 5 5 5 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 RKP03752.1 - 2.7 8.4 60.6 10 6.5 16.9 4.6 2 2 2 4 4 4 0 Fez1 V_ATPase_I PF01496.19 RKP03752.1 - 2.7 5.8 25.1 1.8 6.4 16.9 3.2 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 RKP03752.1 - 6 7.4 77.9 0.98 9.9 7.2 5.9 2 2 3 5 5 5 0 Apg6 coiled-coil region Ins_P5_2-kin PF06090.12 RKP03753.1 - 9.7e-15 54.8 0.0 4.2e-14 52.7 0.0 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase TilS PF09179.11 RKP03753.1 - 2.5 8.6 9.5 0.13 12.8 1.1 3.0 2 0 0 2 2 2 0 TilS substrate binding domain Thg1 PF04446.12 RKP03755.1 - 4.9e-48 162.3 0.0 7.2e-48 161.7 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 RKP03755.1 - 1.2e-36 125.5 0.1 1.7e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain DNA_ligase_A_M PF01068.21 RKP03756.1 - 4.1e-60 202.9 0.0 6.8e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 RKP03756.1 - 1.7e-43 148.9 0.0 3e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 RKP03756.1 - 6.4e-27 94.1 0.0 2.1e-25 89.2 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region MFS_1 PF07690.16 RKP03757.1 - 5.8e-20 71.5 34.0 5.8e-20 71.5 34.0 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RKP03757.1 - 0.00016 20.7 4.7 0.00016 20.7 4.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 RKP03757.1 - 0.00022 20.2 1.2 0.011 14.7 0.2 2.6 3 0 0 3 3 3 2 MFS_1 like family DDDD PF10161.9 RKP03758.1 - 0.038 13.8 0.2 0.068 12.9 0.2 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein DNA_pol_phi PF04931.13 RKP03759.1 - 2e-36 125.4 16.6 4.6e-26 91.2 14.7 5.3 3 1 2 5 5 5 3 DNA polymerase phi TraC_F_IV PF11130.8 RKP03759.1 - 0.067 12.8 4.0 0.24 10.9 0.1 3.1 3 0 0 3 3 3 0 F pilus assembly Type-IV secretion system for plasmid transfer Ribosomal_L1 PF00687.21 RKP03760.1 - 4.6e-07 29.8 1.9 1.4e-06 28.2 0.1 2.7 1 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Mob1_phocein PF03637.17 RKP03761.1 - 3.8e-83 277.6 0.0 4.5e-83 277.4 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol_L_2 PF13656.6 RKP03762.1 - 7.2e-31 105.8 0.0 8.6e-31 105.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RKP03762.1 - 3e-14 52.2 0.0 4.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PIH1 PF08190.12 RKP03763.1 - 3.2e-43 147.1 0.5 5.5e-43 146.3 0.1 1.6 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RKP03763.1 - 6.8e-14 52.1 0.0 1.8e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain KRTAP PF11759.8 RKP03763.1 - 0.47 11.0 22.3 0.81 10.3 22.3 1.3 1 0 0 1 1 1 0 Keratin-associated matrix OPT PF03169.15 RKP03764.1 - 4.5e-135 451.7 55.2 5.2e-135 451.5 55.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MIP PF00230.20 RKP03765.1 - 8.3e-40 136.9 18.3 1e-39 136.6 18.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAS_9 PF13426.7 RKP03767.1 - 1.2e-15 57.6 0.0 1.5e-12 47.7 0.0 3.1 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 RKP03767.1 - 1.6e-06 28.1 0.0 0.073 13.1 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.12 RKP03767.1 - 1.8e-05 24.9 0.0 0.1 12.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 RKP03767.1 - 0.0032 17.7 10.1 1.7 8.9 0.0 5.0 4 2 0 4 4 4 3 PAS fold PAS_8 PF13188.7 RKP03767.1 - 0.009 16.0 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 1 PAS domain Dicty_REP PF05086.12 RKP03767.1 - 0.15 10.0 0.3 0.24 9.3 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chitin_synth_2 PF03142.15 RKP03768.1 - 2.1e-232 772.4 0.0 3.7e-232 771.6 0.0 1.3 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 RKP03768.1 - 4.3e-12 46.4 0.0 4.1e-11 43.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RKP03768.1 - 8.9e-12 45.3 4.1 4.8e-11 42.9 4.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 RKP03768.1 - 0.0075 15.8 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 RKP03768.1 - 0.015 15.1 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 GDI PF00996.18 RKP03769.1 - 6.2e-218 723.6 0.0 7.5e-218 723.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor ubiquitin PF00240.23 RKP03770.1 - 5.7e-175 567.4 34.6 1.5e-33 114.4 0.9 6.0 5 1 1 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 RKP03770.1 - 2.3e-79 261.2 32.8 3e-15 55.8 1.0 6.0 5 1 1 6 6 6 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RKP03770.1 - 5.8e-30 103.6 19.2 3.1e-05 24.4 0.7 7.5 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 RKP03770.1 - 1.1e-19 70.1 9.3 0.025 14.5 0.1 5.3 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 RKP03770.1 - 2.4e-18 66.6 4.9 0.087 13.4 0.1 5.5 1 1 1 5 5 5 5 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 RKP03770.1 - 3.1e-18 65.9 7.0 0.083 13.0 0.0 6.5 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 RKP03770.1 - 4.1e-17 62.3 15.9 0.041 14.2 0.1 5.2 5 0 0 5 5 5 5 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 RKP03770.1 - 5e-12 46.0 1.8 1.2 8.9 0.0 5.2 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 RKP03770.1 - 3.3e-08 33.4 35.5 5 7.2 2.2 10.7 9 1 0 9 9 9 1 Ubiquitin-like domain DUF3861 PF12977.7 RKP03770.1 - 1.2e-07 31.8 7.1 11 6.3 0.0 5.3 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Methyltrans_RNA PF04452.14 RKP03770.1 - 3.3e-07 29.9 2.3 4 6.7 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase DUF2870 PF11069.8 RKP03770.1 - 5.4e-07 29.9 0.0 42 4.6 0.0 5.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 RKP03770.1 - 1.1e-06 28.6 0.1 48 4.1 0.0 5.7 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF493 PF04359.14 RKP03770.1 - 2e-06 28.3 0.3 62 4.3 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF493) Big_7 PF17957.1 RKP03770.1 - 7e-06 26.7 0.3 92 3.9 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain Big_3_3 PF13750.6 RKP03770.1 - 8.4e-06 25.5 0.2 44 3.7 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF1940 PF09155.10 RKP03770.1 - 5.3e-05 23.4 8.7 26 4.9 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1940) Raf1_HTH PF18579.1 RKP03770.1 - 5.4e-05 22.8 3.2 52 3.6 0.0 5.2 5 0 0 5 5 5 0 Rubisco accumulation factor 1 helix turn helix domain UDP-g_GGTase PF06427.11 RKP03770.1 - 6.5e-05 23.0 9.6 11 6.2 0.1 5.1 6 0 0 6 6 5 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 RKP03770.1 - 6.9e-05 22.6 9.9 21 5.0 0.1 5.3 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 RKP03770.1 - 0.00019 21.5 0.0 1.3e+02 2.8 0.0 6.3 6 0 0 6 6 6 0 ORF11CD3 domain DUF969 PF06149.12 RKP03770.1 - 0.0002 20.8 0.1 34 3.8 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 RKP03770.1 - 0.00062 20.3 4.0 1.2e+02 3.4 0.0 5.2 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 RKP03770.1 - 0.00065 18.7 0.0 27 3.5 0.0 4.1 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 RKP03770.1 - 0.04 14.0 9.8 98 3.2 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 RKP03770.1 - 0.25 11.5 36.0 8.5 6.7 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif PI3K_p85B PF02192.16 RKP03770.1 - 0.31 10.8 15.8 51 3.7 0.1 5.3 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Myosin_N PF02736.19 RKP03770.1 - 0.46 10.4 9.4 1.5e+02 2.3 0.0 5.9 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 RKP03770.1 - 4.7 6.9 6.2 3.2e+02 1.0 0.0 4.6 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Phage_sheath_1N PF17481.2 RKP03770.1 - 5.2 7.6 12.7 1.2e+02 3.2 1.3 4.8 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain IFT81_CH PF18383.1 RKP03771.1 - 0.00033 20.9 0.0 0.00083 19.6 0.0 1.6 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain FapA PF03961.13 RKP03771.1 - 0.009 14.7 0.4 2.8 6.4 0.0 2.9 3 0 0 3 3 3 2 Flagellar Assembly Protein A DUF1664 PF07889.12 RKP03771.1 - 0.012 15.6 5.8 0.22 11.5 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 RKP03771.1 - 0.016 15.7 8.9 0.031 14.7 1.7 4.1 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 RKP03771.1 - 0.45 10.5 14.6 2.5 8.1 0.1 3.8 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 RKP03771.1 - 0.93 9.1 6.9 3.6 7.1 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) HALZ PF02183.18 RKP03771.1 - 1.7 9.0 7.8 1.2 9.4 0.3 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3958 PF13125.6 RKP03771.1 - 5.5 7.2 11.9 7.4 6.8 1.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) CENP-F_leu_zip PF10473.9 RKP03771.1 - 7.6 6.6 16.3 1.1 9.3 0.0 4.1 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 RKP03771.1 - 7.6 6.9 9.7 15 6.0 0.7 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 S4 PF01479.25 RKP03772.1 - 2.2e-10 40.1 0.1 3.3e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 RKP03772.1 - 0.049 13.5 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 S4 domain Maf PF02545.14 RKP03774.1 - 5.8e-50 169.4 0.1 7.1e-50 169.1 0.1 1.1 1 0 0 1 1 1 1 Maf-like protein FGGY_C PF02782.16 RKP03774.1 - 0.042 13.6 4.2 0.051 13.3 2.7 1.8 1 1 1 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PFK PF00365.20 RKP03775.1 - 4.8e-180 597.0 0.0 1.2e-92 310.3 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 RKP03775.1 - 0.052 13.2 0.2 0.18 11.4 0.2 2.0 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Nop14 PF04147.12 RKP03778.1 - 0.0068 14.7 36.9 0.0083 14.4 36.9 1.1 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.18 RKP03778.1 - 2.8 7.7 23.3 0.025 14.5 2.8 2.2 1 1 1 2 2 2 0 Myc amino-terminal region Tad PF13400.6 RKP03779.1 - 0.0059 16.9 6.0 0.019 15.3 6.0 1.9 1 0 0 1 1 1 1 Putative Flp pilus-assembly TadE/G-like Dynamitin PF04912.14 RKP03780.1 - 4e-38 131.8 2.1 1.2e-24 87.4 1.5 2.5 3 0 0 3 3 3 2 Dynamitin Spc7 PF08317.11 RKP03780.1 - 0.064 12.1 4.5 0.37 9.6 0.5 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein COMMD1_N PF17221.3 RKP03780.1 - 0.22 11.9 1.5 0.76 10.1 1.5 1.9 1 0 0 1 1 1 0 COMMD1 N-terminal domain DUF1690 PF07956.11 RKP03780.1 - 0.79 10.1 7.5 0.77 10.2 0.2 3.0 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) FliD_N PF02465.18 RKP03780.1 - 0.87 10.3 12.5 0.28 11.9 6.3 3.0 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BST2 PF16716.5 RKP03780.1 - 2.4 8.8 9.9 1.7 9.3 1.0 3.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 RKP03780.1 - 2.4 8.7 5.5 3.4 8.2 2.2 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Sporozoite_P67 PF05642.11 RKP03780.1 - 4.7 5.2 13.3 37 2.2 13.3 2.2 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Acetyltransf_1 PF00583.25 RKP03781.1 - 0.0019 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Catalase PF00199.19 RKP03782.1 - 4.2e-177 589.0 0.1 5.4e-177 588.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RKP03782.1 - 1.6e-19 69.9 0.0 2.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 RKP03782.1 - 1.6e-12 47.3 0.0 2.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 RKP03782.1 - 7.6e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family AAA_12 PF13087.6 RKP03783.1 - 3.5e-34 118.2 0.0 5.9e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKP03783.1 - 3e-24 86.2 0.1 5.5e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKP03783.1 - 1.2e-10 41.9 0.2 1.1e-08 35.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RKP03783.1 - 6.5e-06 26.0 0.1 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RKP03783.1 - 0.00079 19.2 1.0 0.013 15.2 0.0 3.2 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 RKP03783.1 - 0.0027 17.0 0.4 1.1 8.5 0.2 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 RKP03783.1 - 0.043 13.3 0.2 0.13 11.8 0.0 1.9 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 RKP03783.1 - 0.054 13.8 0.7 0.9 9.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 RKP03783.1 - 0.53 10.6 3.1 4.2 7.7 0.2 3.2 3 1 0 3 3 3 0 AAA ATPase domain RRM_1 PF00076.22 RKP03784.1 - 6.6e-37 125.2 1.4 4.2e-18 64.9 0.2 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03784.1 - 7.8e-05 22.7 0.0 0.037 14.1 0.0 3.1 2 2 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 RKP03784.1 - 0.014 15.1 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain NTP_transferase PF00483.23 RKP03784.1 - 0.014 15.0 0.2 0.047 13.3 0.1 1.7 2 0 0 2 2 2 0 Nucleotidyl transferase PHM7_cyt PF14703.6 RKP03784.1 - 0.031 14.5 0.3 2.1 8.5 0.0 2.9 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4078 PF13300.6 RKP03784.1 - 0.043 14.1 0.7 8.8 6.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) DUF3306 PF11748.8 RKP03784.1 - 0.048 14.5 1.6 0.048 14.5 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Bap31 PF05529.12 RKP03785.1 - 2.3e-13 50.2 0.3 3.1e-13 49.8 0.3 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Sec62 PF03839.16 RKP03786.1 - 2.5e-46 157.9 0.1 3.4e-46 157.5 0.1 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 RKP03786.1 - 0.054 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Tudor_4 PF18358.1 RKP03786.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain DUF3413 PF11893.8 RKP03786.1 - 2.5 7.2 7.0 3.5 6.7 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) PRRSV_2b PF07069.11 RKP03786.1 - 4.6 7.8 6.4 1.4 9.5 3.1 1.8 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Upf2 PF04050.14 RKP03787.1 - 6.3e-10 39.9 0.1 7.6e-09 36.4 0.1 2.5 1 1 0 1 1 1 1 Up-frameshift suppressor 2 tRNA_int_endo PF01974.17 RKP03787.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MIF4G PF02854.19 RKP03787.1 - 0.25 11.0 0.0 0.63 9.6 0.0 1.6 1 0 0 1 1 1 0 MIF4G domain RseA_C PF03873.13 RKP03787.1 - 8.8 6.7 8.1 7.4 6.9 1.3 2.8 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain ATG_C PF09333.11 RKP03788.1 - 5.3e-28 97.2 0.3 1.3e-26 92.8 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Harakiri PF15196.6 RKP03788.1 - 0.08 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Activator of apoptosis harakiri HIG_1_N PF04588.13 RKP03790.1 - 3.9e-07 30.2 0.5 5.9e-07 29.6 0.5 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region COX7a PF02238.15 RKP03790.1 - 0.42 11.1 0.3 0.42 11.1 0.3 2.0 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VII Saf_2TM PF18303.1 RKP03791.1 - 6.2 6.4 10.1 11 5.6 1.9 2.5 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Vps16_N PF04841.13 RKP03792.1 - 4e-49 167.5 0.0 6.8e-34 117.3 0.0 3.0 2 1 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 RKP03792.1 - 1.9e-06 27.1 0.2 0.00084 18.5 0.4 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 RKP03792.1 - 0.017 15.4 0.0 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RPN7 PF10602.9 RKP03793.1 - 4.4e-25 88.4 0.0 6.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 RKP03793.1 - 7.3e-13 48.9 0.0 3.5e-12 46.8 0.0 2.2 3 0 0 3 3 3 1 PCI domain CENP-Q PF13094.6 RKP03793.1 - 0.11 12.7 0.9 0.23 11.6 0.9 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RP-C PF03428.13 RKP03793.1 - 0.22 11.2 0.1 0.22 11.2 0.1 2.8 3 2 2 5 5 5 0 Replication protein C N-terminal domain PFU PF09070.11 RKP03794.1 - 8.5e-42 142.0 0.0 1.5e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 RKP03794.1 - 6.2e-40 134.5 6.8 7e-06 26.7 0.0 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 RKP03794.1 - 0.0055 16.7 0.0 13 5.9 0.0 4.1 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 RKP03794.1 - 0.63 10.6 0.1 0.63 10.6 0.1 4.3 3 1 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 RKP03795.1 - 1.1e-19 70.3 19.6 0.001 19.8 0.2 8.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Bromodomain PF00439.25 RKP03795.1 - 1.6e-12 47.3 0.0 2.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 RKP03795.1 - 0.00012 22.3 0.2 34 4.8 0.0 5.2 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKP03795.1 - 0.0043 16.0 0.2 10 5.0 0.1 4.3 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKP03795.1 - 0.012 14.3 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DBR1 PF05011.13 RKP03796.1 - 6.3e-12 46.1 0.0 9.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 RKP03796.1 - 3.2e-05 24.5 0.0 4.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PepSY_2 PF13670.6 RKP03796.1 - 0.78 9.8 3.9 1.6 8.8 3.9 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ADK PF00406.22 RKP03797.1 - 7.7e-48 162.4 0.1 8.9e-48 162.2 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RKP03797.1 - 4.3e-34 117.9 0.1 5.3e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP03797.1 - 3.2e-08 34.2 0.0 4.6e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKP03797.1 - 4.5e-07 30.1 0.0 8.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 RKP03797.1 - 0.0088 15.7 0.2 0.74 9.5 0.2 2.1 1 1 0 1 1 1 1 Thymidylate kinase CoaE PF01121.20 RKP03797.1 - 0.062 13.0 0.2 10 5.7 0.1 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_28 PF13521.6 RKP03797.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 RKP03797.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.6 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain zf-B_box PF00643.24 RKP03798.1 - 1.4e-15 57.1 12.9 3.2e-09 36.8 1.1 2.3 2 0 0 2 2 2 2 B-box zinc finger PriC PF07445.12 RKP03798.1 - 0.033 14.1 2.6 0.079 12.9 2.5 1.5 1 1 0 1 1 1 0 Primosomal replication protein priC OTCace PF00185.24 RKP03799.1 - 5.7e-40 137.0 0.0 7.9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 RKP03799.1 - 2.5e-38 131.4 0.0 4.5e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain XdhC_CoxI PF02625.16 RKP03799.1 - 0.024 14.8 1.9 1.5 9.0 0.0 2.8 1 1 1 2 2 2 0 XdhC and CoxI family OCD_Mu_crystall PF02423.15 RKP03799.1 - 0.036 13.0 0.1 0.058 12.3 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Peptidase_M43 PF05572.13 RKP03801.1 - 1.1e-16 61.0 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 RKP03801.1 - 0.00074 19.7 0.1 0.00083 19.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 RKP03801.1 - 0.0026 17.9 0.1 0.006 16.7 0.1 1.6 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_3 PF13582.6 RKP03801.1 - 0.024 15.1 0.1 0.043 14.3 0.1 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RKP03801.1 - 0.057 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RKP03801.1 - 0.064 13.1 0.2 0.087 12.7 0.2 1.4 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 RKP03801.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 RKP03801.1 - 0.18 11.4 0.0 0.83 9.2 0.0 1.9 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) GIT_SHD PF08518.11 RKP03803.1 - 2.8e-21 74.8 1.1 3.6e-10 39.3 0.3 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF572 PF04502.13 RKP03803.1 - 0.45 10.1 48.1 0.28 10.8 11.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Mem_trans PF03547.18 RKP03803.1 - 3.3 6.0 7.0 0.096 11.1 0.4 1.7 2 0 0 2 2 2 0 Membrane transport protein Chitin_synth_2 PF03142.15 RKP03804.1 - 4e-218 725.3 0.2 5.9e-218 724.7 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 RKP03804.1 - 1.6e-48 165.4 0.0 5e-42 144.0 0.0 2.7 3 0 0 3 3 3 2 Myosin head (motor domain) DEK_C PF08766.11 RKP03804.1 - 3.5e-15 55.6 0.0 1e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 RKP03804.1 - 2.9e-12 46.9 1.7 6.2e-12 45.8 1.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKP03804.1 - 1.5e-10 41.4 0.0 1.6e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RKP03804.1 - 9.3e-05 22.3 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RKP03804.1 - 0.011 15.3 0.0 0.25 10.8 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 21 PRP1_N PF06424.12 RKP03805.1 - 1.7e-34 119.4 0.3 3e-34 118.5 0.3 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 RKP03805.1 - 4.7e-13 48.8 112.4 0.0021 18.7 0.6 16.9 5 3 12 18 18 16 10 Tetratricopeptide repeat TPR_19 PF14559.6 RKP03805.1 - 1.8e-10 41.2 70.2 3.9e-05 24.1 0.3 10.8 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 RKP03805.1 - 1.1e-06 29.2 5.4 1.1e-06 29.2 5.4 10.6 8 2 2 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03805.1 - 3.6e-06 27.0 4.3 0.97 10.0 0.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03805.1 - 1.1e-05 25.2 13.1 6.9 7.0 0.1 9.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKP03805.1 - 0.00094 19.2 0.0 13 6.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_long PF17177.4 RKP03805.1 - 0.01 15.2 0.7 0.6 9.4 0.1 2.8 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP NARP1 PF12569.8 RKP03805.1 - 0.032 13.2 5.0 3.3 6.5 0.1 3.7 5 0 0 5 5 5 0 NMDA receptor-regulated protein 1 baeRF_family12 PF18856.1 RKP03805.1 - 0.048 14.2 1.6 0.11 13.1 1.6 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 TPR_7 PF13176.6 RKP03805.1 - 2.3 8.5 6.4 61 4.0 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Dehydrin PF00257.19 RKP03805.1 - 3 8.4 9.2 0.16 12.5 2.7 2.2 2 0 0 2 2 2 0 Dehydrin UCH PF00443.29 RKP03806.1 - 3.9e-46 157.6 0.0 5.2e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 RKP03806.1 - 9.8e-28 97.1 0.0 2e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 RKP03806.1 - 8.7e-23 81.4 0.0 5.5e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_19 PF14559.6 RKP03807.1 - 1.8e-18 66.8 12.8 0.0044 17.5 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 RKP03807.1 - 5e-17 61.2 60.7 3.9e-05 24.1 0.2 14.3 5 4 11 16 16 16 6 Tetratricopeptide repeat HAT PF02184.16 RKP03807.1 - 5.8e-15 55.0 50.5 0.00028 20.8 0.8 12.4 11 2 0 11 11 10 4 HAT (Half-A-TPR) repeat Suf PF05843.14 RKP03807.1 - 1.7e-13 51.2 1.4 0.0019 18.3 0.0 5.5 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 RKP03807.1 - 1.6e-07 31.3 11.2 0.059 13.4 0.8 7.2 6 3 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 RKP03807.1 - 8.5e-07 28.5 25.8 0.0098 15.1 2.6 5.5 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03807.1 - 1.1e-06 28.2 13.3 13 6.2 0.0 9.8 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKP03807.1 - 5.5e-05 23.5 18.7 1.2 9.9 0.1 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 RKP03807.1 - 0.00027 21.0 4.2 1.1 9.3 0.0 5.1 4 2 2 6 6 6 1 U3 small nucleolar RNA-associated protein 6 MIT PF04212.18 RKP03807.1 - 0.00097 19.2 3.0 0.81 9.8 0.0 4.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 RKP03807.1 - 0.0013 18.6 15.4 0.71 10.0 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 RKP03807.1 - 0.0061 16.9 2.8 4.2 8.0 0.0 6.2 8 0 0 8 8 7 1 Tetratricopeptide repeat Babuvirus_MP PF07234.11 RKP03807.1 - 0.021 15.0 1.1 1.2 9.3 0.1 3.3 2 1 1 3 3 3 0 Movement and RNA silencing protein TPR_5 PF12688.7 RKP03807.1 - 0.19 11.9 3.5 8.7 6.6 0.0 4.6 5 1 0 5 5 5 0 Tetratrico peptide repeat M16C_assoc PF08367.11 RKP03808.1 - 1.3e-41 142.4 0.0 2.1e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 RKP03808.1 - 1.2e-27 97.1 0.0 3.4e-20 72.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RKP03808.1 - 0.001 19.1 0.0 0.0043 17.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) ATP-synt_Z PF16594.5 RKP03808.1 - 0.29 10.7 1.0 0.66 9.5 1.0 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated PPR_2 PF13041.6 RKP03809.1 - 4.1e-18 65.3 0.0 1.2e-09 38.2 0.0 4.0 3 1 1 4 4 4 2 PPR repeat family PPR PF01535.20 RKP03809.1 - 7.3e-16 57.2 1.0 3.4e-06 26.9 0.0 5.7 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 RKP03809.1 - 4.4e-14 51.9 0.0 9.6e-06 25.2 0.0 4.7 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 RKP03809.1 - 9.7e-14 51.2 0.0 0.00081 19.4 0.0 3.7 3 0 0 3 3 3 3 Pentatricopeptide repeat domain TPR_19 PF14559.6 RKP03809.1 - 1.9e-09 37.9 0.8 0.0084 16.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR_long PF17177.4 RKP03809.1 - 8.7e-08 31.8 0.1 0.00052 19.4 0.0 2.5 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 RKP03809.1 - 0.00065 20.3 12.3 18 6.5 0.0 7.9 6 2 3 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKP03809.1 - 0.087 12.0 1.8 1.4 8.1 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP13 PF12921.7 RKP03809.1 - 0.15 11.9 0.0 17 5.3 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ATPase expression SNAP PF14938.6 RKP03810.1 - 3e-27 95.8 13.2 3.7e-27 95.5 13.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP YfdX PF10938.8 RKP03810.1 - 0.04 13.8 0.2 0.04 13.8 0.2 2.3 2 0 0 2 2 2 0 YfdX protein SnoaL_2 PF12680.7 RKP03810.1 - 2.7 8.7 6.0 1 10.0 0.3 2.8 2 1 0 2 2 2 0 SnoaL-like domain TPR_12 PF13424.6 RKP03810.1 - 6.8 7.1 23.3 0.38 11.1 6.6 4.4 2 2 2 4 4 4 0 Tetratricopeptide repeat NSF PF02071.20 RKP03810.1 - 9.1 7.6 24.4 9.8 7.5 0.1 6.9 6 2 2 8 8 8 0 Aromatic-di-Alanine (AdAR) repeat CorA PF01544.18 RKP03811.1 - 1.2e-13 51.0 6.2 1.1e-08 34.8 0.0 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Mito_carr PF00153.27 RKP03812.1 - 2.2e-51 171.7 0.5 5e-16 58.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Mg_trans_NIPA PF05653.14 RKP03813.1 - 9.3e-106 353.2 15.3 1.1e-105 353.0 15.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 RKP03813.1 - 0.00034 20.8 6.8 0.00034 20.8 6.8 3.6 3 1 0 3 3 3 2 EamA-like transporter family DUF2304 PF10066.9 RKP03813.1 - 0.044 14.0 1.2 0.044 14.0 1.2 3.5 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2304) SLATT_1 PF18181.1 RKP03813.1 - 0.083 12.8 0.7 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Pan3_PK PF18101.1 RKP03814.1 - 1.3e-56 190.4 0.0 2.2e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 RKP03814.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03814.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 RKP03815.1 - 3e-07 30.1 0.0 7.3e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 RKP03815.1 - 0.00043 20.6 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 RKP03815.1 - 0.15 12.1 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UbiA PF01040.18 RKP03816.1 - 6.6e-57 192.7 29.0 8.6e-57 192.3 29.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1129 PF06570.11 RKP03816.1 - 2.2 7.7 5.9 0.34 10.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Met_10 PF02475.16 RKP03817.1 - 5.3e-60 202.6 0.0 7.5e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 RKP03817.1 - 0.0021 17.3 0.0 0.0044 16.2 0.0 1.4 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase CTNNBL PF08216.11 RKP03818.1 - 1.7e-24 86.0 0.0 4.1e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Pkinase PF00069.25 RKP03819.1 - 3e-17 62.8 0.0 3.5e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03819.1 - 4.3e-07 29.5 0.0 7.3e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP03819.1 - 0.0068 15.2 0.0 0.012 14.4 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase DUF4096 PF13340.6 RKP03819.1 - 0.068 13.4 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) PT PF04886.12 RKP03820.1 - 0.94 9.1 10.0 2.5 7.7 10.0 1.7 1 0 0 1 1 1 0 PT repeat EMP24_GP25L PF01105.24 RKP03821.1 - 5.2e-36 124.3 0.0 5.8e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SEP PF08059.13 RKP03822.1 - 2.3e-25 88.9 0.0 5e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 RKP03822.1 - 4.7e-15 55.5 0.0 7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain V-SNARE PF05008.15 RKP03823.1 - 6.7e-13 48.8 0.2 1.6e-12 47.6 0.2 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 RKP03823.1 - 1.5e-12 47.6 2.5 6.2e-12 45.6 1.8 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF4407 PF14362.6 RKP03823.1 - 1.2e-08 34.7 2.6 2.7e-08 33.6 2.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Sec20 PF03908.13 RKP03823.1 - 3.8e-06 26.7 0.7 1.1e-05 25.3 0.2 2.1 2 1 0 2 2 2 1 Sec20 Spc7 PF08317.11 RKP03823.1 - 0.0019 17.1 2.5 0.052 12.4 0.2 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein CARMIL_C PF16000.5 RKP03823.1 - 0.01 15.5 2.3 0.02 14.5 2.3 1.5 1 1 0 1 1 1 0 CARMIL C-terminus Fusion_gly PF00523.18 RKP03823.1 - 0.035 12.4 0.2 0.47 8.6 0.2 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 SNARE PF05739.19 RKP03823.1 - 0.048 13.6 3.3 0.048 13.6 3.3 2.9 3 0 0 3 3 3 0 SNARE domain ApoLp-III PF07464.11 RKP03823.1 - 0.11 12.6 0.3 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TMEM156 PF15106.6 RKP03823.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 TMEM156 protein family Baculo_PEP_C PF04513.12 RKP03823.1 - 0.25 11.4 2.3 1.4 9.0 0.1 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4763 PF15960.5 RKP03823.1 - 0.78 9.0 3.1 8.8 5.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ArgJ PF01960.18 RKP03824.1 - 7e-146 485.8 8.2 7.9e-146 485.6 8.2 1.0 1 0 0 1 1 1 1 ArgJ family AD PF09793.9 RKP03825.1 - 2.4e-18 66.0 0.0 4.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain LSM14 PF12701.7 RKP03825.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain ARID PF01388.21 RKP03826.1 - 4e-15 56.3 0.0 4e-15 56.3 0.0 2.4 2 1 0 2 2 1 1 ARID/BRIGHT DNA binding domain TFIIA PF03153.13 RKP03826.1 - 0.0002 21.5 45.5 0.00038 20.6 45.5 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 RKP03826.1 - 0.018 14.6 17.8 0.033 13.7 17.8 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 RKP03826.1 - 0.021 13.8 6.8 0.035 13.1 6.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Velvet PF11754.8 RKP03826.1 - 0.036 14.0 14.7 0.11 12.4 14.7 1.8 1 0 0 1 1 1 0 Velvet factor PAT1 PF09770.9 RKP03826.1 - 0.24 9.6 42.0 0.35 9.1 42.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.7 RKP03826.1 - 0.32 10.7 19.4 0.56 9.9 19.4 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit eIF3_subunit PF08597.10 RKP03826.1 - 0.35 10.7 18.3 0.65 9.9 18.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PTPRCAP PF15713.5 RKP03826.1 - 0.41 10.9 19.4 0.91 9.8 19.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PIP5K PF01504.18 RKP03826.1 - 0.42 9.8 14.8 0.75 9.0 14.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CSG2 PF16965.5 RKP03826.1 - 0.43 9.5 10.4 0.7 8.8 10.4 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator RR_TM4-6 PF06459.12 RKP03826.1 - 0.43 10.3 23.4 0.69 9.7 23.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 RKP03826.1 - 0.49 9.8 9.5 1 8.7 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 RKP03826.1 - 0.64 9.0 22.3 0.96 8.4 22.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SWI-SNF_Ssr4 PF08549.10 RKP03826.1 - 0.72 8.4 22.9 1.3 7.6 22.9 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Zip PF02535.22 RKP03826.1 - 0.76 8.9 5.9 1.4 8.0 5.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FliP PF00813.20 RKP03826.1 - 1.4 8.8 11.9 2.7 7.8 11.9 1.4 1 0 0 1 1 1 0 FliP family Mem_trans PF03547.18 RKP03826.1 - 1.5 7.2 4.4 2.5 6.4 4.4 1.3 1 0 0 1 1 1 0 Membrane transport protein CemA PF03040.14 RKP03826.1 - 1.6 8.6 8.7 22 4.9 10.7 1.7 2 0 0 2 2 2 0 CemA family FAM60A PF15396.6 RKP03826.1 - 1.7 8.6 15.5 3 7.8 15.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 RKP03826.1 - 1.8 7.3 18.1 2.7 6.7 18.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Rrn6 PF10214.9 RKP03826.1 - 1.8 6.9 24.5 2.9 6.3 24.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LAP1C PF05609.12 RKP03826.1 - 2.3 7.2 21.3 3.5 6.6 21.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S15 PF02129.18 RKP03826.1 - 2.4 7.7 14.0 4.9 6.7 14.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Presenilin PF01080.17 RKP03826.1 - 2.9 6.6 30.0 4.3 6.0 30.0 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 RKP03826.1 - 3.3 6.5 15.4 4.9 6.0 15.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BORG_CEP PF14957.6 RKP03826.1 - 3.5 8.8 18.6 8.9 7.5 18.6 1.6 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 RKP03826.1 - 3.8 6.2 18.9 5.9 5.6 18.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pannexin_like PF12534.8 RKP03826.1 - 4.3 6.3 18.1 6.3 5.8 18.1 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF5427 PF10310.9 RKP03826.1 - 4.7 6.1 27.4 7 5.5 27.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CPSF100_C PF13299.6 RKP03826.1 - 5.3 7.2 16.3 12 6.0 16.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ATG7_N PF16420.5 RKP03826.1 - 6.8 6.2 12.3 11 5.6 12.3 1.2 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus CCSAP PF15748.5 RKP03826.1 - 6.9 6.8 28.3 13 5.9 28.3 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated LMBR1 PF04791.16 RKP03826.1 - 8.5 5.2 11.3 12 4.6 11.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 RKP03826.1 - 8.8 5.8 24.5 14 5.1 24.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cyclin PF08613.11 RKP03827.1 - 0.032 14.6 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin Ribosomal_S28e PF01200.18 RKP03828.1 - 1.1e-29 102.2 3.8 1.3e-29 102.0 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Snf7 PF03357.21 RKP03829.1 - 1e-45 155.4 17.3 1e-45 155.4 17.3 1.6 2 0 0 2 2 2 1 Snf7 Fe_dep_repr_C PF02742.15 RKP03829.1 - 0.043 13.9 0.8 0.076 13.1 0.1 2.0 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain MscS_TM PF12794.7 RKP03829.1 - 0.65 8.8 2.0 1.1 8.1 2.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RmlD_sub_bind PF04321.17 RKP03831.1 - 2.4e-54 184.4 2.7 3.8e-54 183.7 2.7 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 RKP03831.1 - 3.6e-21 75.7 0.0 7.6e-21 74.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RKP03831.1 - 5.7e-12 45.7 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RKP03831.1 - 3e-10 39.7 0.1 1.5e-09 37.4 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 RKP03831.1 - 2.5e-05 23.6 0.0 6.5e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Serinc PF03348.15 RKP03832.1 - 1.6e-131 439.2 0.1 1.8e-131 439.0 0.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Pkinase PF00069.25 RKP03834.1 - 1e-69 234.8 0.0 1.5e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03834.1 - 2.5e-30 105.6 0.0 3.4e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 RKP03834.1 - 5.1e-13 49.5 3.4 1.3e-12 48.2 3.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 RKP03834.1 - 4.9e-07 29.4 0.2 4.5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 RKP03834.1 - 4.5e-06 26.9 0.3 0.0001 22.6 0.1 2.8 3 0 0 3 3 3 1 C2 domain Haspin_kinase PF12330.8 RKP03834.1 - 0.00029 19.9 0.1 0.00041 19.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 RKP03834.1 - 0.0028 17.3 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKP03834.1 - 0.01 15.8 0.1 0.051 13.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 RKP03836.1 - 7.8e-37 127.8 0.1 1.2e-36 127.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKP03836.1 - 3.6e-16 59.3 0.1 6.1e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Elong-fact-P_C PF09285.11 RKP03837.1 - 6.8e-14 51.3 0.1 2.4e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 RKP03837.1 - 1.9e-09 37.4 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 RKP03837.1 - 1.7e-07 31.2 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF2149 PF09919.9 RKP03837.1 - 0.051 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) ABC_tran PF00005.27 RKP03838.1 - 2.3e-26 93.0 0.0 3.4e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RKP03838.1 - 5.8e-08 32.9 0.3 0.00018 21.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 RKP03838.1 - 0.0024 17.8 0.0 0.0051 16.8 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain SMC_N PF02463.19 RKP03838.1 - 0.0028 17.1 0.3 0.037 13.5 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RKP03838.1 - 0.0088 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 RKP03838.1 - 0.015 15.0 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 RKP03838.1 - 0.035 14.5 0.2 0.068 13.6 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 RKP03838.1 - 0.053 14.0 0.5 1.1 9.7 0.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 RKP03838.1 - 0.12 12.6 0.4 2.3 8.5 0.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit GLTSCR1 PF15249.6 RKP03839.1 - 0.053 14.0 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein Beach PF02138.18 RKP03840.1 - 2e-121 404.6 0.1 3.2e-121 403.9 0.1 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 RKP03840.1 - 2.2e-12 46.9 0.5 5.2e-12 45.7 0.1 1.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 RKP03840.1 - 4.9e-09 36.5 0.1 1.3e-08 35.1 0.1 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.21 RKP03840.1 - 2e-05 24.6 10.9 5.2e-05 23.3 10.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF4704 PF15787.5 RKP03840.1 - 0.0026 17.1 2.0 0.0026 17.1 2.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4704) WD40 PF00400.32 RKP03840.1 - 0.013 16.4 2.6 24 6.0 0.3 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF3361 PF11841.8 RKP03840.1 - 6.9 6.6 9.6 16 5.4 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DUF4834 PF16118.5 RKP03841.1 - 0.52 11.3 1.9 0.76 10.8 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 RKP03841.1 - 1.9 8.0 7.2 2.8 7.5 7.2 1.2 1 0 0 1 1 1 0 Spt20 family RA PF00788.23 RKP03842.1 - 4.9e-05 23.9 0.0 8.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain His_biosynth PF00977.21 RKP03843.1 - 1.3e-43 149.1 0.5 2.7e-42 144.8 0.5 2.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 RKP03843.1 - 1.2e-19 70.9 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 RKP03843.1 - 8.5e-08 32.0 0.0 2.1e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 RKP03843.1 - 2.6e-06 27.4 0.0 5.5e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family TMP-TENI PF02581.17 RKP03843.1 - 0.0035 16.7 0.1 1.1 8.6 0.0 3.3 3 0 0 3 3 3 1 Thiamine monophosphate synthase Peptidase_C26 PF07722.13 RKP03843.1 - 0.035 13.9 0.1 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase C26 Peptidase_U32_C PF16325.5 RKP03844.1 - 1.3 9.3 4.0 11 6.3 0.1 3.4 3 0 0 3 3 3 0 Peptidase family U32 C-terminal domain ZnuA PF01297.17 RKP03844.1 - 1.8 7.9 21.9 0.81 9.0 7.0 2.6 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic WD40 PF00400.32 RKP03845.1 - 6.2e-10 39.5 6.4 0.00014 22.6 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03845.1 - 4.5e-05 23.7 0.0 0.09 13.1 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 RKP03845.1 - 0.022 13.4 0.0 0.087 11.4 0.0 1.8 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_2 PF13360.6 RKP03845.1 - 0.027 14.1 0.1 0.15 11.7 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.8 RKP03845.1 - 0.061 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RKP03845.1 - 0.12 11.1 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Sec63 PF02889.16 RKP03846.1 - 5.6e-25 88.0 0.0 1.2e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 RKP03846.1 - 3.3e-18 65.6 0.2 3.3e-18 65.6 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain AAA PF00004.29 RKP03847.1 - 5.9e-55 185.3 0.0 4.5e-40 137.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 RKP03847.1 - 8.3e-11 42.3 0.0 9.3e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 RKP03847.1 - 5.7e-10 38.9 0.1 1.1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RKP03847.1 - 1.8e-09 38.0 0.0 0.00018 21.8 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 RKP03847.1 - 4.2e-08 33.8 0.1 0.0046 17.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 RKP03847.1 - 5.6e-07 29.1 0.1 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 RKP03847.1 - 2.1e-06 27.8 0.0 0.001 19.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 RKP03847.1 - 2.4e-06 27.4 0.1 0.0068 16.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 RKP03847.1 - 2.6e-06 27.5 0.0 0.049 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 RKP03847.1 - 3e-06 27.1 0.4 0.036 13.8 0.1 3.1 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 RKP03847.1 - 1.1e-05 25.7 0.0 0.041 14.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 RKP03847.1 - 1.5e-05 25.3 0.0 0.039 14.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 RKP03847.1 - 3.1e-05 24.0 0.3 5.9 6.7 0.0 4.1 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea TsaE PF02367.17 RKP03847.1 - 9e-05 22.5 0.0 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 RKP03847.1 - 9.8e-05 21.8 0.4 0.0085 15.5 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 RKP03847.1 - 0.00011 21.9 0.5 0.0014 18.3 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 RKP03847.1 - 0.00035 21.1 0.0 0.027 15.0 0.0 2.8 2 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 RKP03847.1 - 0.00041 20.1 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 RKP03847.1 - 0.0005 19.5 0.9 0.0057 16.0 0.1 2.6 2 1 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 RKP03847.1 - 0.00051 19.8 0.1 0.69 9.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 RKP03847.1 - 0.00052 19.6 0.1 0.024 14.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 RKP03847.1 - 0.00082 18.8 0.1 0.24 10.8 0.0 3.2 2 1 0 3 3 3 1 Bacterial TniB protein Parvo_NS1 PF01057.17 RKP03847.1 - 0.00099 18.3 0.0 0.8 8.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NACHT PF05729.12 RKP03847.1 - 0.0016 18.4 1.6 5.4 6.9 0.0 3.6 3 1 1 4 4 3 0 NACHT domain CDC48_N PF02359.18 RKP03847.1 - 0.0019 18.3 0.0 0.006 16.7 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.6 RKP03847.1 - 0.0021 17.6 3.1 1.5 8.3 0.0 3.8 2 2 1 4 4 4 1 AAA domain ABC_tran PF00005.27 RKP03847.1 - 0.0028 18.2 0.8 0.31 11.6 0.1 2.9 3 0 0 3 3 3 1 ABC transporter CPT PF07931.12 RKP03847.1 - 0.003 17.4 0.0 0.054 13.3 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 RKP03847.1 - 0.013 14.7 0.1 2.9 7.0 0.1 2.7 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 RKP03847.1 - 0.017 14.6 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 RKP03847.1 - 0.031 14.5 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 RKP03847.1 - 0.034 13.3 0.1 7 5.7 0.0 2.8 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.6 RKP03847.1 - 0.09 12.6 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 RKP03847.1 - 0.091 12.5 0.1 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 RKP03847.1 - 0.11 12.2 1.0 0.62 9.8 0.0 2.6 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 RKP03847.1 - 0.13 12.6 0.2 0.99 9.7 0.0 2.5 4 0 0 4 4 2 0 AAA domain WD40 PF00400.32 RKP03848.1 - 3.8e-10 40.2 16.1 0.4 11.6 0.1 9.3 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP03848.1 - 1.8e-05 24.9 0.0 0.009 16.3 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP03848.1 - 0.005 15.6 0.0 1.9 7.0 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 RKP03848.1 - 0.11 13.0 1.7 0.68 10.4 0.0 3.2 5 0 0 5 5 5 0 EF-hand domain pair Aminotran_4 PF01063.19 RKP03849.1 - 5.9e-28 98.2 0.0 7.2e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV HATPase_c PF02518.26 RKP03850.1 - 6e-23 81.5 0.0 1.3e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 RKP03850.1 - 1.1e-22 80.2 0.1 2.6e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 RKP03850.1 - 5e-06 26.5 0.1 5e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 RKP03850.1 - 0.0021 18.7 0.1 0.047 14.3 0.0 3.3 2 1 0 2 2 2 1 GAF domain Casc1_N PF15927.5 RKP03852.1 - 1.5e-13 50.9 10.7 2.4e-13 50.3 10.7 1.3 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus tRNA-synt_1 PF00133.22 RKP03853.1 - 2.7e-33 115.1 0.1 3.3e-21 75.2 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RKP03853.1 - 2.3e-18 66.1 0.0 1.6e-07 30.4 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RKP03853.1 - 6.6e-12 45.6 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RKP03853.1 - 1.1e-10 41.4 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RKP03853.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF413 PF04219.12 RKP03853.1 - 0.033 14.2 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF DEP PF00610.21 RKP03854.1 - 1.5e-05 25.0 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 RKP03854.1 - 0.00014 22.1 0.0 0.0005 20.3 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.27 RKP03854.1 - 0.00099 19.0 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RRM_1 PF00076.22 RKP03855.1 - 4.1e-09 36.1 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP03855.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 RKP03855.1 - 0.26 11.2 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif CTD_bind PF04818.13 RKP03856.1 - 1.6e-05 25.6 0.0 3.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. M11L PF11099.8 RKP03856.1 - 0.033 14.5 0.5 0.069 13.4 0.5 1.6 1 1 0 1 1 1 0 Apoptosis regulator M11L like TetR_C_20 PF17925.1 RKP03856.1 - 0.28 11.5 6.5 2.1 8.7 0.2 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1631 PF07793.11 RKP03856.1 - 0.3 9.4 11.2 0.049 12.1 7.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Herpes_UL32 PF06070.11 RKP03856.1 - 6.5 4.4 11.2 8.6 4.0 11.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Aph-1 PF06105.12 RKP03858.1 - 1.3e-50 171.9 17.1 1.6e-50 171.7 17.1 1.0 1 0 0 1 1 1 1 Aph-1 protein V-SNARE_C PF12352.8 RKP03860.1 - 5.4e-08 33.0 1.3 5.4e-08 33.0 1.3 2.6 3 2 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RKP03860.1 - 5.2e-05 23.1 2.2 5.2e-05 23.1 2.2 2.1 2 0 0 2 2 2 1 Sec20 DUF5089 PF17002.5 RKP03860.1 - 0.017 15.0 4.0 0.017 15.0 4.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) GATase PF00117.28 RKP03860.1 - 0.053 13.3 0.1 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 Glutamine amidotransferase class-I Fusion_gly PF00523.18 RKP03860.1 - 0.077 11.2 5.0 0.051 11.8 1.8 1.9 2 0 0 2 2 2 0 Fusion glycoprotein F0 ING PF12998.7 RKP03860.1 - 2.2 8.9 8.7 3.3 8.3 0.6 3.2 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding SH3_9 PF14604.6 RKP03861.1 - 2.8e-05 23.9 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP03861.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain LAP1C PF05609.12 RKP03861.1 - 0.0052 15.9 1.7 0.0074 15.4 1.7 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) SH3_2 PF07653.17 RKP03861.1 - 0.031 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Amnionless PF14828.6 RKP03861.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4381 PF14316.6 RKP03861.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Apt1 PF10351.9 RKP03861.1 - 2.6 6.8 6.5 3.7 6.3 6.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 RKP03863.1 - 2.8e-17 63.2 23.2 2.8e-17 63.2 23.2 3.9 4 1 0 4 4 4 1 BUD22 eIF-5a PF01287.20 RKP03864.1 - 6.5e-27 93.4 0.2 9.5e-27 92.9 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 RKP03864.1 - 0.0013 18.7 0.1 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EF-hand_4 PF12763.7 RKP03865.1 - 3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand TMF_TATA_bd PF12325.8 RKP03865.1 - 0.0059 16.8 0.3 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF3391 PF11871.8 RKP03866.1 - 4.6 7.8 11.8 2 8.9 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Dpy-30 PF05186.13 RKP03867.1 - 0.00021 20.9 0.9 0.22 11.2 0.1 2.4 2 0 0 2 2 2 2 Dpy-30 motif MMPL PF03176.15 RKP03867.1 - 4 6.3 9.5 5 6.0 9.5 1.2 1 0 0 1 1 1 0 MMPL family MITF_TFEB_C_3_N PF15951.5 RKP03867.1 - 6.2 7.4 10.1 0.62 10.7 4.6 2.0 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus ETF PF01012.21 RKP03869.1 - 4.2e-41 140.8 10.4 6.6e-41 140.2 10.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 RKP03869.1 - 1.4e-35 121.2 1.4 3.7e-35 119.8 1.4 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ESCRT-II PF05871.12 RKP03870.1 - 1.2e-43 148.7 0.0 1.7e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit dsDNA_bind PF01984.20 RKP03870.1 - 0.15 12.3 0.9 0.7 10.2 0.9 1.9 1 1 0 1 1 1 0 Double-stranded DNA-binding domain TilS PF09179.11 RKP03870.1 - 2.3 8.8 6.5 17 6.0 1.7 3.1 2 1 1 3 3 3 0 TilS substrate binding domain Methyltransf_PK PF05891.12 RKP03871.1 - 1.1e-69 234.4 0.0 1.2e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 RKP03871.1 - 5.1e-10 39.9 0.0 1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKP03871.1 - 1.1e-08 35.7 0.0 2.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKP03871.1 - 1.6e-08 35.1 0.0 2.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKP03871.1 - 4.1e-07 30.0 0.0 7.9e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 RKP03871.1 - 2.8e-05 23.5 0.0 4.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 RKP03871.1 - 0.16 11.5 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain CLP1_P PF16575.5 RKP03872.1 - 8.3e-41 139.9 0.0 7.7e-38 130.2 0.0 2.2 1 1 1 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 RKP03872.1 - 1.1e-23 83.9 0.0 2.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 RKP03872.1 - 1.9e-14 53.6 1.9 1.1e-07 31.9 0.0 2.6 1 1 1 2 2 2 2 N-terminal beta-sandwich domain of polyadenylation factor PduV-EutP PF10662.9 RKP03872.1 - 3.2e-05 23.7 0.0 0.0067 16.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 RKP03872.1 - 0.0002 21.3 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 RKP03872.1 - 0.005 16.9 0.0 0.027 14.6 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RKP03872.1 - 0.012 16.2 0.0 0.46 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 RKP03872.1 - 0.028 13.9 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 RKP03872.1 - 0.03 14.7 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 RKP03872.1 - 0.04 13.6 0.0 0.19 11.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 RKP03872.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 RKP03872.1 - 0.069 13.4 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 RKP03872.1 - 0.1 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 RKP03872.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 RKP03873.1 - 5e-26 91.6 0.0 8.9e-26 90.8 0.0 1.4 1 1 0 1 1 1 1 Septin SH3_9 PF14604.6 RKP03873.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKP03873.1 - 4.6e-09 35.7 0.0 7.4e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain GTP_EFTU PF00009.27 RKP03873.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKP03873.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RKP03873.1 - 0.0098 16.3 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 RKP03873.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Hema_stalk PF08720.10 RKP03873.1 - 0.082 12.6 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk RsgA_GTPase PF03193.16 RKP03873.1 - 0.17 11.8 0.1 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Aminotran_5 PF00266.19 RKP03874.1 - 5.9e-17 61.7 0.0 1.2e-16 60.6 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RKP03874.1 - 0.077 12.3 1.2 0.11 11.7 1.2 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glycos_transf_2 PF00535.26 RKP03875.1 - 1.4e-18 67.2 0.0 1.2e-17 64.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RKP03875.1 - 2.1e-05 24.5 0.2 0.57 10.0 0.1 3.4 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Ysc84 PF04366.12 RKP03876.1 - 3e-33 114.3 0.1 7.9e-33 112.9 0.0 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_1 PF00018.28 RKP03876.1 - 8.6e-15 54.1 0.0 1.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKP03876.1 - 7.1e-12 44.8 0.0 1.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 RKP03876.1 - 3.4e-11 42.8 0.2 5.7e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain RNA_pol_Rpb2_6 PF00562.28 RKP03877.1 - 2e-120 402.5 0.3 2.8e-120 402.0 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RKP03877.1 - 3.8e-50 170.2 0.0 5.6e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 RKP03877.1 - 1e-29 102.7 0.1 2.3e-29 101.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 RKP03877.1 - 4.3e-24 84.6 1.6 1.2e-23 83.2 1.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 RKP03877.1 - 2.3e-20 72.5 0.0 5.2e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 RKP03877.1 - 3.9e-17 62.5 0.0 7.7e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 RKP03877.1 - 6.2e-10 39.5 0.2 1.5e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rubredoxin_2 PF18073.1 RKP03877.1 - 4 7.3 7.0 11 5.8 7.0 1.8 1 0 0 1 1 1 0 Rubredoxin metal binding domain Pkinase PF00069.25 RKP03878.1 - 1.4e-71 240.9 0.0 1.6e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03878.1 - 1.8e-35 122.5 0.0 2.9e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKP03878.1 - 0.0037 16.7 0.1 0.0073 15.7 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP03878.1 - 0.0039 17.2 0.0 0.091 12.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2322 PF10084.9 RKP03878.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) NADH_B2 PF14813.6 RKP03879.1 - 0.00038 20.2 0.1 0.00049 19.8 0.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Med10 PF09748.9 RKP03880.1 - 5.7e-28 97.3 0.0 6.3e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex HTH_31 PF13560.6 RKP03880.1 - 0.027 14.8 0.1 0.052 13.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Aminotran_1_2 PF00155.21 RKP03882.1 - 1.3e-32 113.4 0.0 1.8e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RKP03882.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase L51_S25_CI-B8 PF05047.16 RKP03883.1 - 3.5e-06 26.8 0.0 7.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SH3_2 PF07653.17 RKP03884.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain PAT1 PF09770.9 RKP03884.1 - 3.3 5.9 12.0 4.1 5.5 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 RKP03884.1 - 3.9 7.4 15.7 5.9 6.8 15.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 RKP03885.1 - 1.3e-47 161.9 0.0 2.4e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP03885.1 - 8.1e-25 87.3 0.0 1.2e-23 83.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RKP03885.1 - 1e-15 57.7 0.1 2e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RKP03885.1 - 6.5e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKP03885.1 - 9.2e-05 21.8 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase YEATS PF03366.16 RKP03886.1 - 2.6e-12 46.5 0.0 4.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family SDA1 PF05285.12 RKP03886.1 - 2 7.7 11.2 2.8 7.3 11.2 1.2 1 0 0 1 1 1 0 SDA1 Rtt106 PF08512.12 RKP03887.1 - 9.4e-15 54.8 0.0 3.7e-14 52.9 0.0 1.9 2 1 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 RKP03887.1 - 0.063 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain RRM_1 PF00076.22 RKP03889.1 - 1.4e-13 50.4 0.0 4.9e-11 42.3 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DsbD PF02683.15 RKP03889.1 - 0.013 15.4 0.2 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Peptidase_S41 PF03572.18 RKP03889.1 - 0.21 11.2 0.6 0.45 10.1 0.6 1.5 1 0 0 1 1 1 0 Peptidase family S41 FHA PF00498.26 RKP03890.1 - 1.5e-16 60.5 0.0 3.7e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RKP03890.1 - 0.00014 22.1 0.2 0.0011 19.2 0.0 2.5 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain HALZ PF02183.18 RKP03890.1 - 0.12 12.6 3.9 0.3 11.3 3.9 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper FAM217 PF15344.6 RKP03890.1 - 0.4 10.6 3.8 1.2 9.1 3.8 1.7 1 0 0 1 1 1 0 FAM217 family Filament PF00038.21 RKP03890.1 - 1.3 8.5 11.2 0.13 11.8 2.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein Proteasome PF00227.26 RKP03892.1 - 8.5e-43 146.0 0.0 9.7e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4908 PF16252.5 RKP03892.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) NAC PF01849.18 RKP03893.1 - 5.8e-08 32.6 0.5 9.9e-08 31.9 0.5 1.5 1 0 0 1 1 1 1 NAC domain Acyl-CoA_dh_1 PF00441.24 RKP03894.1 - 5.4e-42 143.5 0.2 1.1e-41 142.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RKP03894.1 - 6e-36 123.5 0.0 1e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RKP03894.1 - 7.3e-24 83.8 0.0 1.4e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKP03894.1 - 7.2e-14 52.2 0.2 7.2e-14 52.2 0.2 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pex24p PF06398.11 RKP03897.1 - 6.5e-16 58.3 0.0 8.9e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Wzy_C_2 PF11846.8 RKP03897.1 - 0.078 12.9 2.0 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal UFD1 PF03152.14 RKP03898.1 - 1.1e-71 239.9 0.0 1.2e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 IMS PF00817.20 RKP03899.1 - 9.3e-41 139.3 0.0 2.4e-40 138.0 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family Porphobil_deam PF01379.20 RKP03900.1 - 2e-76 256.1 0.0 2.8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 RKP03900.1 - 2.8e-11 43.6 0.0 7.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Cyclin_N PF00134.23 RKP03901.1 - 2.5e-30 104.8 0.0 5.4e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RKP03901.1 - 3.6e-06 27.0 2.7 3.6e-06 27.0 2.7 4.0 4 1 1 5 5 5 1 Cyclin, C-terminal domain SUIM_assoc PF16619.5 RKP03901.1 - 5.8 7.1 65.2 1.2 9.3 9.8 6.2 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 RasGAP PF00616.19 RKP03902.1 - 8.3e-27 94.3 0.0 1e-16 61.3 0.0 2.4 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 RKP03902.1 - 2.1e-09 37.7 0.1 5.5e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 RKP03902.1 - 0.00081 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain MOR2-PAG1_C PF14225.6 RKP03902.1 - 0.021 14.7 0.5 0.1 12.5 0.0 2.4 2 0 0 2 2 2 0 Cell morphogenesis C-terminal TrmO_C PF18389.1 RKP03903.1 - 1 9.5 3.3 0.52 10.5 0.2 2.0 2 0 0 2 2 2 0 TrmO C-terminal domain DUF1279 PF06916.13 RKP03904.1 - 3.5e-08 33.9 0.0 4.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Glyco_transf_4 PF13439.6 RKP03905.1 - 0.089 12.8 4.7 0.16 12.0 0.3 2.7 3 0 0 3 3 3 0 Glycosyltransferase Family 4 FH2 PF02181.23 RKP03906.1 - 1.1e-46 159.7 0.0 2.2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain DEAD PF00270.29 RKP03907.1 - 1.4e-46 158.5 0.0 3.2e-46 157.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP03907.1 - 9.5e-25 87.1 0.0 4.7e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RKP03907.1 - 1.1e-14 54.4 0.1 3.4e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RKP03907.1 - 1.5e-06 28.3 0.0 2.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-PARP PF00645.18 RKP03910.1 - 4.1e-14 53.2 0.0 7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Glyco_hydro_18 PF00704.28 RKP03911.1 - 2e-56 192.0 0.0 2.3e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CoA_trans PF01144.23 RKP03912.1 - 1.6e-102 341.5 1.7 1.9e-68 230.1 0.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase DUF4579 PF15158.6 RKP03915.1 - 0.059 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) UreE_C PF05194.12 RKP03915.1 - 0.086 13.3 7.6 0.26 11.8 7.6 1.8 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain SelP_N PF04592.14 RKP03915.1 - 0.65 9.4 5.6 0.91 8.9 5.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2796 PF10986.8 RKP03915.1 - 5.1 7.0 9.7 7.8 6.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) ATP_bind_1 PF03029.17 RKP03916.1 - 1.6e-77 260.5 0.7 2e-77 260.3 0.2 1.4 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 RKP03916.1 - 4.7e-06 27.1 0.0 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 RKP03916.1 - 1.4e-05 25.2 0.0 0.00017 21.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKP03916.1 - 1.4e-05 24.7 0.1 9.3e-05 22.0 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 RKP03916.1 - 4.4e-05 22.6 0.1 0.0068 15.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RKP03916.1 - 0.00015 21.5 0.2 0.64 9.6 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 RKP03916.1 - 0.00017 21.5 0.0 0.00066 19.6 0.0 1.9 1 1 0 1 1 1 1 NTPase FeoB_N PF02421.18 RKP03916.1 - 0.00037 20.0 0.0 0.0056 16.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF87 PF01935.17 RKP03916.1 - 0.0011 19.1 0.1 0.0031 17.7 0.0 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 RKP03916.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 RKP03916.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.14 RKP03916.1 - 0.0018 17.6 0.0 0.0072 15.6 0.0 1.8 1 1 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.6 RKP03916.1 - 0.0018 18.8 0.0 0.008 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RKP03916.1 - 0.0022 17.2 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 RKP03916.1 - 0.003 17.7 1.6 0.0038 17.4 0.2 2.2 2 1 0 2 2 1 1 AAA domain MipZ PF09140.11 RKP03916.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 RKP03916.1 - 0.0043 17.0 0.1 1.7 8.5 0.1 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 RKP03916.1 - 0.0066 16.2 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKP03916.1 - 0.0067 16.0 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 RKP03916.1 - 0.0073 16.0 0.1 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 RKP03916.1 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 RKP03916.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 RKP03916.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_31 PF13614.6 RKP03916.1 - 0.022 14.7 0.2 1.4 8.8 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RKP03916.1 - 0.04 13.9 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RKP03916.1 - 0.04 14.3 0.1 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 RKP03916.1 - 0.054 13.2 0.6 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain CLP1_P PF16575.5 RKP03916.1 - 0.056 13.2 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 RKP03916.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 RKP03916.1 - 0.066 12.4 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Viral_helicase1 PF01443.18 RKP03916.1 - 0.066 12.9 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 RKP03916.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 RKP03916.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 RKP03916.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain ParA PF10609.9 RKP03916.1 - 0.19 11.1 3.2 2.1 7.7 0.1 2.7 3 0 0 3 3 3 0 NUBPL iron-transfer P-loop NTPase UCH PF00443.29 RKP03917.1 - 1.7e-50 171.9 0.0 2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKP03917.1 - 2.7e-23 83.1 0.0 1.8e-15 57.4 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 RKP03917.1 - 0.024 14.1 2.3 20 4.5 0.0 3.2 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase IBR PF01485.21 RKP03917.1 - 0.087 13.1 1.0 7.2 6.9 0.3 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 RKP03918.1 - 2e-68 230.7 0.0 2.8e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03918.1 - 2.9e-49 167.7 0.0 4.7e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP03918.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4704 PF15787.5 RKP03918.1 - 0.35 10.1 4.0 1.3 8.2 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4704) bZIP_1 PF00170.21 RKP03919.1 - 2.1e-05 24.5 7.6 3.6e-05 23.8 1.9 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 RKP03919.1 - 0.014 15.5 3.5 0.014 15.5 3.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 RKP03919.1 - 0.88 10.1 3.8 1.6 9.2 3.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Serglycin PF04360.12 RKP03919.1 - 0.9 9.5 7.7 2.2 8.2 7.7 1.7 1 0 0 1 1 1 0 Serglycin SIKE PF05769.11 RKP03919.1 - 3 7.7 5.5 1.4 8.8 2.2 1.8 2 0 0 2 2 2 0 SIKE family Plus-3 PF03126.18 RKP03920.1 - 4.3e-24 85.1 0.0 8.7e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain DUF733 PF05306.11 RKP03920.1 - 0.25 11.7 11.2 0.074 13.4 6.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF733) Sec34 PF04136.15 RKP03921.1 - 2.2e-34 118.5 0.0 3.1e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Sec34-like family DSPc PF00782.20 RKP03922.1 - 9.5e-11 41.6 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKP03922.1 - 9.9e-05 22.0 0.0 0.00029 20.5 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RKP03922.1 - 0.0023 18.1 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RKP03922.1 - 0.098 12.6 0.5 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.12 RKP03922.1 - 0.22 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF442 PF04273.13 RKP03922.1 - 0.29 11.2 0.0 0.29 11.2 0.0 3.1 4 0 0 4 4 4 0 Putative phosphatase (DUF442) Pep1_7 PF17232.2 RKP03922.1 - 0.33 11.4 1.4 0.4 11.2 0.2 1.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 ApbA_C PF08546.11 RKP03925.1 - 4.6e-26 91.5 0.0 1.1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 RKP03925.1 - 1.1e-25 90.0 0.0 1.8e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TBCC PF07986.12 RKP03926.1 - 5.8e-20 71.2 0.0 1.6e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 RKP03926.1 - 2.7e-05 24.6 0.0 4.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DASH_Hsk3 PF08227.11 RKP03926.1 - 0.81 10.1 4.4 0.46 10.9 0.6 2.6 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like C12orf66_like PF09404.10 RKP03927.1 - 2.4e-17 62.9 0.0 2e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 KICSTOR complex C12orf66 like Rotamase PF00639.21 RKP03928.1 - 5.8e-23 81.7 0.0 7.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RKP03928.1 - 7.7e-18 65.1 0.0 9.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 RKP03928.1 - 2.2e-06 27.7 0.6 7e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 RKP03928.1 - 4.6e-06 27.5 0.0 5.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain UDPGP PF01704.18 RKP03930.1 - 2.5e-192 639.1 0.0 2.8e-192 638.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_S24e PF01282.19 RKP03932.1 - 4.1e-29 100.4 0.0 9e-29 99.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S24e CEP44 PF15007.6 RKP03933.1 - 5e-40 136.6 0.0 7e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 DUF3417 PF11897.8 RKP03934.1 - 1.6 9.2 5.6 8.9 6.8 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) SchA_CurD PF04486.12 RKP03934.1 - 2.3 8.4 5.3 1.7 8.8 0.6 2.7 3 0 0 3 3 3 0 SchA/CurD like domain HycH PF07450.11 RKP03934.1 - 9.5 6.6 8.0 0.72 10.2 1.1 2.4 2 1 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH iPGM_N PF06415.13 RKP03935.1 - 3.9e-75 252.0 0.0 5.2e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 RKP03935.1 - 7.9e-73 244.9 0.0 9.1e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 RKP03935.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 RKP03935.1 - 0.00034 20.3 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Suf PF05843.14 RKP03936.1 - 5.2e-05 23.4 0.0 0.31 11.0 0.0 4.4 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_7 PF13176.6 RKP03936.1 - 0.052 13.6 1.4 1.3 9.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKP03936.1 - 0.33 11.2 0.1 0.33 11.2 0.1 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RKP03936.1 - 0.75 9.8 4.8 17 5.4 0.0 4.5 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 RKP03936.1 - 1.2 9.7 3.9 5.1 7.7 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 RKP03938.1 - 7e-13 48.4 5.8 1.2e-07 31.8 0.2 2.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKP03938.1 - 7.5e-10 38.7 14.5 0.00017 21.9 0.9 3.3 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP03938.1 - 1.2e-09 38.1 11.9 6.9e-05 23.4 0.5 3.3 2 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKP03938.1 - 3.2e-06 27.3 0.9 0.084 13.2 0.0 3.1 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 RKP03938.1 - 1.2e-05 25.0 4.7 0.024 14.5 0.2 3.0 2 1 1 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 RKP03938.1 - 7e-05 22.7 11.9 0.34 11.0 0.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 RKP03938.1 - 0.00013 21.7 2.9 0.14 12.1 0.5 2.2 1 1 1 2 2 2 2 Rad50 zinc hook motif zf-met PF12874.7 RKP03938.1 - 0.00024 21.4 2.3 0.2 12.1 0.0 3.3 2 1 1 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 RKP03938.1 - 0.00026 21.2 10.3 0.01 16.1 6.1 2.2 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 RKP03938.1 - 0.00037 20.3 3.9 0.41 10.5 1.1 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C2H2_3rep PF18868.1 RKP03938.1 - 0.003 18.2 8.4 0.23 12.1 1.5 2.1 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats Prok-RING_1 PF14446.6 RKP03938.1 - 0.0043 17.0 0.6 2.4 8.2 0.2 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 UBZ_FAAP20 PF15750.5 RKP03938.1 - 0.0069 16.3 0.7 3.3 7.7 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-binding zinc-finger zf-C2H2_2 PF12756.7 RKP03938.1 - 0.01 16.1 5.3 0.29 11.5 2.7 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 RKP03938.1 - 0.019 15.2 2.3 0.83 10.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon zf-C3HC4_3 PF13920.6 RKP03938.1 - 0.031 14.1 3.3 2.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 RKP03938.1 - 0.041 13.6 1.0 0.041 13.6 1.0 3.4 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Zn-C2H2_12 PF18112.1 RKP03938.1 - 0.054 14.0 6.0 0.68 10.5 0.1 3.0 3 1 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain TRAF6_Z2 PF18048.1 RKP03938.1 - 0.064 13.4 4.3 5.3 7.2 0.0 3.4 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_11 PF16622.5 RKP03938.1 - 0.078 12.8 0.9 0.078 12.8 0.9 2.6 3 1 0 3 3 3 0 zinc-finger C2H2-type DUF2225 PF09986.9 RKP03938.1 - 0.14 11.9 0.3 2.1 8.0 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_4 PF14570.6 RKP03938.1 - 0.18 11.6 3.6 6.9 6.6 0.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 RKP03938.1 - 0.24 11.4 5.8 10 6.1 0.0 2.3 2 0 0 2 2 2 0 zinc-RING finger domain GAGA PF09237.11 RKP03938.1 - 0.31 10.9 5.5 0.85 9.5 0.6 2.3 1 1 1 2 2 2 0 GAGA factor zf_ZIC PF18366.1 RKP03938.1 - 0.37 10.9 4.6 4.6 7.4 1.4 3.0 1 1 2 3 3 3 0 Zic proteins zinc finger domain HAMP PF00672.25 RKP03939.1 - 1.1e-46 157.0 32.3 7e-07 29.5 0.1 9.8 9 1 1 10 10 9 8 HAMP domain Response_reg PF00072.24 RKP03939.1 - 5.6e-25 87.7 0.0 1.2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 RKP03939.1 - 1.1e-23 83.9 0.0 4.6e-23 81.9 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Baculo_PEP_C PF04513.12 RKP03939.1 - 6.4e-12 45.7 18.9 0.1 12.6 0.1 7.7 2 1 6 8 8 7 5 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1759 PF03564.15 RKP03939.1 - 5.9e-07 29.5 0.2 8.3 6.3 0.0 6.3 6 0 0 6 6 6 2 Protein of unknown function (DUF1759) Zw10 PF06248.13 RKP03939.1 - 1.1e-05 24.2 0.1 5.7 5.4 0.0 5.1 2 2 1 5 5 5 1 Centromere/kinetochore Zw10 IL32 PF15225.6 RKP03939.1 - 0.00067 20.0 0.1 82 3.7 0.0 6.5 6 0 0 6 6 6 0 Interleukin 32 HisKA PF00512.25 RKP03939.1 - 0.0043 17.1 3.5 0.017 15.2 0.3 3.9 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain Integrin_beta PF00362.18 RKP03939.1 - 0.005 16.5 0.1 12 5.4 0.0 4.2 5 0 0 5 5 5 0 Integrin beta chain VWA domain Mer2 PF09074.10 RKP03939.1 - 0.014 15.2 1.0 0.14 11.9 0.1 2.9 3 0 0 3 3 3 0 Mer2 SoDot-IcmSS PF16848.5 RKP03939.1 - 0.02 14.9 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative DUF2397 PF09660.10 RKP03939.1 - 0.021 13.8 1.1 0.18 10.7 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2397) HATPase_c_3 PF13589.6 RKP03939.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Skp1_POZ PF03931.15 RKP03939.1 - 0.022 14.9 1.8 30 4.9 0.0 4.8 5 0 0 5 5 5 0 Skp1 family, tetramerisation domain ATG16 PF08614.11 RKP03939.1 - 0.079 13.2 0.8 0.52 10.5 0.8 2.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3829 PF12889.7 RKP03939.1 - 0.18 11.2 0.5 2e+02 1.3 0.0 4.5 5 1 0 5 5 5 0 Protein of unknown function (DUF3829) BORCS6 PF10157.9 RKP03939.1 - 1.3 9.3 16.4 55 4.0 0.0 7.3 6 2 1 7 7 7 0 BLOC-1-related complex sub-unit 6 COG2 PF06148.11 RKP03939.1 - 4.9 7.2 19.8 55 3.9 0.1 7.2 6 2 1 8 8 8 0 COG (conserved oligomeric Golgi) complex component, COG2 Rad21_Rec8_N PF04825.13 RKP03940.1 - 5.1e-24 84.6 0.0 8e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 RKP03940.1 - 4.7e-05 22.6 0.0 9.3e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Hexapep PF00132.24 RKP03941.1 - 5.2e-13 48.2 8.9 4.5e-06 26.2 2.1 4.8 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RKP03941.1 - 7.5e-05 22.4 6.8 0.049 13.4 0.6 4.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Cohesin_load PF10345.9 RKP03942.1 - 0.00094 17.7 0.0 0.57 8.6 0.0 2.1 2 0 0 2 2 2 2 Cohesin loading factor TPR_2 PF07719.17 RKP03942.1 - 0.064 13.4 3.0 0.6 10.4 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2076 PF09849.9 RKP03943.1 - 3.5e-07 30.6 26.7 2.3e-06 27.9 26.5 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 RKP03943.1 - 1.2e-05 25.3 8.1 1.6e-05 24.9 8.1 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 RKP03943.1 - 0.84 9.7 7.0 1.4 8.9 7.0 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HEAT PF02985.22 RKP03944.1 - 0.0001 22.3 6.8 3 8.4 0.1 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 RKP03944.1 - 0.00068 20.0 4.6 0.0091 16.4 0.2 4.5 4 2 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 RKP03944.1 - 0.0078 16.7 7.4 0.4 11.2 1.3 4.6 4 0 0 4 4 4 1 HEAT-like repeat CCAP PF11105.8 RKP03944.1 - 0.19 11.7 0.0 6.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Arthropod cardioacceleratory peptide 2a Adaptin_N PF01602.20 RKP03944.1 - 0.24 9.9 0.0 0.55 8.7 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region PC_rep PF01851.22 RKP03944.1 - 4.1 8.0 5.0 23 5.7 3.1 3.0 2 0 0 2 2 2 0 Proteasome/cyclosome repeat DUF2462 PF09495.10 RKP03945.1 - 2.7e-08 34.4 14.7 2.7e-08 34.4 14.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) eRF1_1 PF03463.15 RKP03946.1 - 1.8e-44 150.8 0.2 6.2e-44 149.1 0.4 1.8 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 RKP03946.1 - 1.3e-30 106.4 0.3 2.6e-30 105.4 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RKP03946.1 - 1.1e-23 83.8 0.1 5e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 eRF1 domain 3 ROK PF00480.20 RKP03946.1 - 0.045 13.2 0.1 7.8 5.9 0.0 2.2 1 1 1 2 2 2 0 ROK family HPTransfase PF10090.9 RKP03946.1 - 0.059 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain HA2 PF04408.23 RKP03947.1 - 1.7e-21 76.5 0.9 6.8e-21 74.6 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 RKP03947.1 - 3.8e-17 62.4 0.0 9.6e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 RKP03947.1 - 4e-13 49.7 0.0 8.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKP03947.1 - 2.7e-08 33.8 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RKP03947.1 - 0.00012 22.4 0.2 0.00042 20.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKP03947.1 - 0.00085 19.7 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKP03947.1 - 0.0018 18.0 0.0 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 RKP03947.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SSE PF00437.20 RKP03947.1 - 0.028 13.5 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 RKP03947.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 RKP03947.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 RKP03947.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 RKP03947.1 - 0.076 13.0 0.0 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 RKP03947.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 RKP03947.1 - 0.14 12.3 1.6 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RKP03947.1 - 0.18 12.3 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 RKP03947.1 - 0.25 11.2 0.7 1.6 8.6 0.2 2.2 2 0 0 2 2 2 0 NACHT domain DUF4201 PF13870.6 RKP03948.1 - 1.8 8.3 6.7 9.7 5.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) MCD PF05292.11 RKP03949.1 - 2.7e-65 220.5 0.0 4.6e-39 134.5 0.0 2.1 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain LRR_8 PF13855.6 RKP03950.1 - 6.8e-28 96.2 29.3 2.6e-10 39.9 3.4 3.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 RKP03950.1 - 6e-15 55.1 7.1 5e-06 26.8 1.7 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP03950.1 - 1.8e-05 24.6 5.8 4.4 8.2 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 RKP03950.1 - 0.0018 17.8 3.3 0.0056 16.2 2.8 1.9 1 1 1 2 2 2 1 Leucine-rich repeat zf-C2H2_2 PF12756.7 RKP03950.1 - 0.14 12.5 0.1 2.6 8.4 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ABC_membrane_2 PF06472.15 RKP03951.1 - 5.3e-34 117.9 0.7 5.7e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RKP03951.1 - 1.2e-18 68.0 0.0 2.4e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RKP03951.1 - 0.01 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 RKP03951.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 RKP03951.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 RKP03951.1 - 0.2 11.2 0.1 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 RKP03951.1 - 0.27 10.0 0.0 0.46 9.2 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Cyt-b5 PF00173.28 RKP03952.1 - 3.2e-14 52.8 0.1 4.3e-14 52.4 0.1 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Iwr1 PF08574.10 RKP03953.1 - 5.5e-10 40.1 2.7 5.5e-10 40.1 2.7 2.8 3 0 0 3 3 3 1 Transcription factor Iwr1 MMtag PF10159.9 RKP03954.1 - 3.9e-31 107.1 1.2 5.1e-31 106.8 1.2 1.1 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Hydrolase_4 PF12146.8 RKP03956.1 - 0.00099 18.4 0.0 0.01 15.1 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 RKP03956.1 - 0.0028 17.3 0.0 0.004 16.8 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Pantoate_ligase PF02569.15 RKP03957.1 - 2.4e-93 312.2 0.0 2.8e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase BPL_LplA_LipB PF03099.19 RKP03958.1 - 3.2e-09 36.8 0.0 5.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PX PF00787.24 RKP03959.1 - 3.3e-15 56.1 0.3 7.5e-15 54.9 0.3 1.7 1 0 0 1 1 1 1 PX domain PXA PF02194.15 RKP03959.1 - 9.6e-13 48.5 0.1 3.5e-12 46.7 0.1 2.0 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 RKP03959.1 - 9.4e-06 26.2 0.3 0.0021 18.6 0.0 3.1 2 0 0 2 2 2 1 Sorting nexin C terminal Kinesin PF00225.23 RKP03960.1 - 1.4e-107 359.5 0.8 2.9e-107 358.4 0.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKP03960.1 - 1.3e-22 80.4 0.3 3.3e-22 79.0 0.3 1.8 1 0 0 1 1 1 1 Microtubule binding HAP1_N PF04849.13 RKP03960.1 - 0.0024 17.2 13.3 0.0024 17.2 13.3 4.4 3 1 0 4 4 4 2 HAP1 N-terminal conserved region Bap31_Bap29_C PF18035.1 RKP03960.1 - 0.095 12.7 0.1 0.095 12.7 0.1 6.1 7 1 0 7 7 7 0 Bap31/Bap29 cytoplasmic coiled-coil domain DASH_Dam1 PF08653.10 RKP03960.1 - 1.3 8.9 8.5 18 5.2 0.2 5.0 5 0 0 5 5 5 0 DASH complex subunit Dam1 Cyclin PF08613.11 RKP03961.1 - 0.012 16.0 0.2 0.058 13.8 0.0 2.1 1 1 1 2 2 2 0 Cyclin Pkinase PF00069.25 RKP03963.1 - 4e-64 216.5 0.0 4.6e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03963.1 - 2.6e-49 167.8 0.0 3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP03963.1 - 2.1e-05 23.5 0.0 3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase TSCPD PF12637.7 RKP03963.1 - 0.0031 17.7 0.1 0.0072 16.5 0.1 1.6 1 0 0 1 1 1 1 TSCPD domain Kinase-like PF14531.6 RKP03963.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 RKP03963.1 - 0.091 11.7 0.1 1.4 7.8 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain CAP_N PF01213.19 RKP03964.1 - 6e-91 305.2 2.2 3.2e-89 299.6 2.2 2.2 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 RKP03964.1 - 1.5e-55 187.1 4.5 2.1e-55 186.7 4.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 RKP03964.1 - 0.016 14.9 2.4 0.14 11.9 0.4 2.2 1 1 2 3 3 3 0 Tubulin binding cofactor C zf-C2H2_9 PF16293.5 RKP03964.1 - 0.18 11.7 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) HSP20 PF00011.21 RKP03965.1 - 5.5e-09 36.1 0.1 5.8e-07 29.6 0.1 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 RKP03965.1 - 0.0062 17.5 0.0 0.011 16.8 0.0 1.5 1 1 0 1 1 1 1 CS domain hDGE_amylase PF14701.6 RKP03966.1 - 3.7e-139 464.6 0.0 5.3e-139 464.1 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 RKP03966.1 - 1.6e-98 330.1 0.0 2.6e-98 329.4 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 RKP03966.1 - 3.1e-36 125.4 0.0 5.8e-36 124.5 0.0 1.4 1 1 0 1 1 1 1 Central domain of human glycogen debranching enzyme DUF3402 PF11882.8 RKP03967.1 - 1.7e-58 198.9 0.0 7e-57 193.6 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 RKP03967.1 - 3e-37 128.4 0.0 1.9e-18 66.6 0.0 2.8 3 0 0 3 3 3 2 N1221-like protein zf-C3HC4 PF00097.25 RKP03968.1 - 2e-08 34.0 6.3 3.2e-08 33.3 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP03968.1 - 2.8e-08 33.6 6.4 5.3e-08 32.7 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 RKP03968.1 - 7.4e-08 32.1 7.2 1.3e-07 31.3 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP03968.1 - 1.5e-07 31.1 9.2 2.7e-07 30.3 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKP03968.1 - 1.9e-07 31.1 7.4 3.3e-07 30.4 7.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 RKP03968.1 - 8e-07 28.9 7.9 1.4e-06 28.2 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RKP03968.1 - 1.9e-06 28.1 10.5 3.4e-06 27.3 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RKP03968.1 - 0.00019 21.2 7.9 0.00047 19.9 7.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 RKP03968.1 - 0.0087 15.9 3.8 0.017 14.9 3.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 RKP03968.1 - 0.024 14.9 8.1 0.058 13.7 8.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 RKP03968.1 - 0.038 13.9 2.3 0.068 13.0 2.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 RKP03968.1 - 0.099 12.7 2.6 0.2 11.7 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 RKP03968.1 - 0.59 10.3 3.5 1.3 9.3 3.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 RKP03968.1 - 2.7 7.8 7.1 5.7 6.8 7.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Spectrin PF00435.21 RKP03968.1 - 3.1 8.3 10.1 4.6 7.8 5.0 2.4 2 0 0 2 2 2 0 Spectrin repeat TP6A_N PF04406.14 RKP03971.1 - 5.4e-17 61.5 0.1 9.2e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase MtrB PF05440.12 RKP03974.1 - 0.0025 18.2 0.2 0.076 13.4 0.0 2.2 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase subunit B ApoLp-III PF07464.11 RKP03974.1 - 1.8 8.7 11.4 0.06 13.4 3.1 2.3 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 RKP03974.1 - 2.7 7.9 19.6 2.7 7.8 0.9 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain FliS PF02561.14 RKP03974.1 - 3.3 8.0 9.7 8.5 6.7 0.9 2.9 2 1 1 3 3 3 0 Flagellar protein FliS Helicase_C PF00271.31 RKP03975.1 - 7.2e-26 90.7 0.0 1.3e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKP03975.1 - 6.4e-22 78.2 0.1 9.5e-21 74.3 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RKP03975.1 - 0.0085 16.1 0.0 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 RKP03976.1 - 2.4e-38 132.0 0.0 3.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP03976.1 - 2.8e-13 49.8 0.0 4.3e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 RKP03976.1 - 0.085 12.8 2.1 0.26 11.2 0.1 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family Globin PF00042.22 RKP03977.1 - 0.0073 16.9 0.0 0.022 15.3 0.0 1.7 1 1 0 1 1 1 1 Globin CBM_21 PF03370.13 RKP03978.1 - 3.8e-19 68.9 0.0 8.6e-19 67.8 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 RKP03978.1 - 9.1e-06 26.2 0.0 0.063 13.9 0.1 2.4 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) AF-4 PF05110.13 RKP03978.1 - 0.84 7.7 6.6 1.6 6.7 6.6 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.13 RKP03979.1 - 0.056 13.4 19.6 0.078 13.0 19.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4106 PF13388.6 RKP03979.1 - 0.37 10.0 22.7 0.55 9.4 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PNISR PF15996.5 RKP03979.1 - 0.48 10.7 14.8 0.029 14.7 9.3 1.7 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Neur_chan_memb PF02932.16 RKP03979.1 - 0.54 10.3 4.7 0.76 9.8 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 RKP03979.1 - 0.86 8.3 11.7 1.1 7.9 11.7 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 RKP03979.1 - 1.3 8.2 4.8 0.47 9.6 1.7 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 RKP03979.1 - 1.5 8.6 13.7 2.2 8.1 13.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.14 RKP03979.1 - 1.8 8.3 5.9 2.9 7.6 5.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TP53IP5 PF15331.6 RKP03979.1 - 2.2 8.4 5.0 3.8 7.6 5.0 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Lin-8 PF03353.15 RKP03979.1 - 2.5 7.6 14.0 3.2 7.2 14.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TERB2 PF15101.6 RKP03979.1 - 4.4 7.3 16.3 7.3 6.6 16.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 RKP03979.1 - 9.4 5.8 28.0 15 5.1 28.0 1.3 1 0 0 1 1 1 0 Spt20 family Perilipin PF03036.16 RKP03981.1 - 0.022 13.8 8.4 0.029 13.4 8.4 1.1 1 0 0 1 1 1 0 Perilipin family RAB3GAP2_N PF14655.6 RKP03981.1 - 2.9 7.1 5.7 3.8 6.7 5.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AMP-binding PF00501.28 RKP03982.1 - 1.5e-52 178.6 0.2 2.5e-52 177.9 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKP03982.1 - 0.0026 18.7 3.0 0.0036 18.2 1.4 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tim44 PF04280.15 RKP03983.1 - 1.5e-28 99.8 0.0 3.8e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DCP2 PF05026.13 RKP03984.1 - 9.2e-26 90.0 3.2 1.4e-25 89.5 3.2 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 RKP03984.1 - 5.9e-15 55.5 0.0 9.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 RKP03984.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain 2OG-Fe_Oxy_2 PF10014.9 RKP03984.1 - 0.16 11.7 0.1 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe dioxygenase Nop16 PF09420.10 RKP03985.1 - 6.1e-28 98.3 6.6 1.4e-25 90.5 6.6 2.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Nif11 PF07862.11 RKP03985.1 - 0.07 13.5 2.0 2.9 8.3 0.2 2.8 2 0 0 2 2 2 0 Nif11 domain Rhabdo_ncap PF00945.18 RKP03985.1 - 0.83 8.5 4.3 1.8 7.3 0.7 2.2 1 1 1 2 2 2 0 Rhabdovirus nucleocapsid protein Stm1_N PF09598.10 RKP03990.1 - 0.3 11.9 0.1 0.3 11.9 0.1 3.0 2 0 0 2 2 2 0 Stm1 Arm PF00514.23 RKP03990.1 - 10 6.4 13.2 35 4.6 0.1 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat NAD_binding_1 PF00175.21 RKP03991.1 - 1.6e-10 41.6 0.0 1.3e-06 29.0 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 RKP03991.1 - 0.01 16.0 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain SNF2_N PF00176.23 RKP03993.1 - 6.7e-60 202.7 0.0 1.4e-59 201.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 RKP03993.1 - 2.1e-46 159.1 1.6 2.1e-46 159.1 1.6 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) HEAT PF02985.22 RKP03993.1 - 1.2e-17 62.5 9.5 0.08 13.2 0.0 10.0 10 0 0 10 10 10 5 HEAT repeat Helicase_C PF00271.31 RKP03993.1 - 1.3e-16 61.0 0.0 3.4e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 RKP03993.1 - 5.9e-05 23.4 21.5 0.27 11.7 0.8 7.5 6 3 1 7 7 7 2 HEAT repeats TAF6_C PF07571.13 RKP03993.1 - 0.00085 19.6 0.3 7.6 6.9 0.0 5.2 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 RKP03993.1 - 0.00097 19.7 0.0 0.023 15.3 0.0 3.0 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 RKP03993.1 - 0.028 14.3 0.1 0.16 11.9 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 RKP03993.1 - 0.16 12.5 26.1 9.1 6.9 0.0 9.8 12 1 1 13 13 12 0 HEAT-like repeat UME PF08064.13 RKP03993.1 - 0.17 11.8 0.7 5.6 6.9 0.2 3.7 3 1 1 4 4 4 0 UME (NUC010) domain Adaptin_N PF01602.20 RKP03993.1 - 0.43 9.1 1.6 6.3 5.2 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region Pribosyl_synth PF14572.6 RKP03994.1 - 2e-41 142.1 0.5 1.2e-34 119.9 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 RKP03994.1 - 4.2e-40 136.3 0.0 2.2e-39 134.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 RKP03994.1 - 1.2e-11 44.4 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PEX11 PF05648.14 RKP03995.1 - 9.6e-47 159.3 0.0 1.1e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) G-patch PF01585.23 RKP03996.1 - 2.2e-09 37.0 0.3 4.3e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RKP03996.1 - 0.0025 17.9 0.2 0.0025 17.9 0.2 2.3 2 0 0 2 2 1 1 G-patch domain GAGA_bind PF06217.12 RKP03996.1 - 0.021 15.1 8.4 0.24 11.7 1.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 RKP03996.1 - 0.083 12.7 9.2 0.81 9.5 0.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Snf7 PF03357.21 RKP03996.1 - 0.098 12.2 12.7 0.033 13.8 7.0 2.6 3 0 0 3 3 3 0 Snf7 NAM-associated PF14303.6 RKP03996.1 - 0.1 13.3 23.0 0.089 13.5 5.1 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 RKP03996.1 - 0.46 10.1 28.4 0.59 9.7 9.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NARP1 PF12569.8 RKP03996.1 - 0.61 8.9 18.2 0.47 9.3 6.3 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF3439 PF11921.8 RKP03996.1 - 1.2 9.2 21.7 0.095 12.7 12.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) NST1 PF13945.6 RKP03996.1 - 2.5 8.2 16.8 1.3 9.1 6.9 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Vfa1 PF08432.10 RKP03996.1 - 2.7 8.3 17.9 5.2 7.4 4.7 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF719 PF05334.13 RKP03996.1 - 3 8.0 20.4 2.6 8.2 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF2052 PF09747.9 RKP03996.1 - 4.1 7.5 6.9 5.7 7.0 1.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AP3D1 PF06375.11 RKP03996.1 - 5.5 7.2 14.9 5.1 7.3 1.9 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF2229 PF09989.9 RKP03996.1 - 5.9 6.5 7.3 4.4 6.9 0.9 2.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) MRP-L47 PF06984.13 RKP03997.1 - 9.7e-25 86.5 0.1 1.3e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GspL_C PF12693.7 RKP03997.1 - 0.017 14.9 0.5 0.034 14.0 0.5 1.5 1 0 0 1 1 1 0 GspL periplasmic domain Acetyltransf_7 PF13508.7 RKP03998.1 - 2.4e-08 34.3 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKP03998.1 - 7.8e-07 29.1 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKP03998.1 - 1.4e-06 28.5 0.0 5.7e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 RKP03998.1 - 0.001 19.2 0.1 0.0024 18.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain eIF3_subunit PF08597.10 RKP03999.1 - 4.9e-46 157.6 20.2 5.5e-46 157.5 20.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SH3BGR PF04908.15 RKP03999.1 - 0.053 13.7 1.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein PBP1_TM PF14812.6 RKP03999.1 - 0.19 12.1 11.1 3.2 8.2 0.2 3.3 2 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal D5_N PF08706.11 RKP03999.1 - 1.8 8.8 5.4 0.87 9.8 1.9 2.0 2 0 0 2 2 2 0 D5 N terminal like Med6 PF04934.14 RKP04000.1 - 1.4e-33 115.5 0.0 1.7e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF4255 PF14065.6 RKP04000.1 - 0.05 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) Peptidase_M16 PF00675.20 RKP04001.1 - 3.6e-51 173.1 1.6 6.2e-51 172.3 1.6 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RKP04001.1 - 1.9e-36 125.8 0.0 4.6e-35 121.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain zf-HIT PF04438.16 RKP04002.1 - 5.5e-07 29.3 9.5 8.6e-07 28.7 9.5 1.3 1 0 0 1 1 1 1 HIT zinc finger Mu-like_Pro PF10123.9 RKP04002.1 - 0.0058 16.2 1.4 0.0072 15.9 1.4 1.1 1 0 0 1 1 1 1 Mu-like prophage I protein C1_2 PF03107.16 RKP04002.1 - 0.06 13.7 4.0 0.12 12.7 4.0 1.5 1 0 0 1 1 1 0 C1 domain Nif11 PF07862.11 RKP04002.1 - 0.21 11.9 0.5 0.21 11.9 0.5 2.1 2 0 0 2 2 2 0 Nif11 domain zf-MYND PF01753.18 RKP04002.1 - 0.31 11.2 13.6 0.71 10.0 13.6 1.6 1 0 0 1 1 1 0 MYND finger PolC_DP2 PF03833.13 RKP04002.1 - 0.54 8.1 2.2 0.71 7.7 2.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2012 PF09430.10 RKP04003.1 - 5.1e-29 100.9 0.0 6.8e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 RKP04003.1 - 0.00033 20.6 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 RKP04003.1 - 0.00037 20.7 0.1 0.00059 20.1 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 RKP04003.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II RNF220 PF15926.5 RKP04004.1 - 3.6e-23 82.5 0.3 5.8e-22 78.5 0.4 2.2 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 RKP04004.1 - 2.1e-10 40.3 8.5 2.1e-10 40.3 8.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKP04004.1 - 1.3e-05 25.0 6.4 1.3e-05 25.0 6.4 2.9 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 RKP04004.1 - 2.6e-05 24.0 13.2 6.2e-05 22.8 6.5 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RKP04004.1 - 3.2e-05 23.7 6.2 3.2e-05 23.7 6.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP04004.1 - 0.00055 19.7 7.1 0.00055 19.7 7.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP04004.1 - 0.0036 17.3 7.6 0.0036 17.3 7.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 RKP04004.1 - 0.021 15.2 9.4 0.021 15.2 9.4 2.7 3 0 0 3 3 3 0 Ring finger domain zf-ANAPC11 PF12861.7 RKP04004.1 - 0.18 11.9 5.9 0.1 12.7 2.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_12 PF18658.1 RKP04004.1 - 0.2 11.2 5.4 3.5 7.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RKP04004.1 - 0.61 10.6 5.9 0.67 10.5 2.9 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_10 PF16685.5 RKP04004.1 - 0.83 9.8 12.4 0.24 11.6 6.5 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 RKP04004.1 - 2.5 7.9 13.6 0.61 9.9 3.3 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 RKP04004.1 - 5.7 6.9 9.4 0.97 9.3 1.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf_UBZ PF18439.1 RKP04004.1 - 8.3 6.1 8.4 1.5 8.5 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger CDC45 PF02724.14 RKP04005.1 - 3.1e-170 567.6 1.1 3.6e-170 567.4 1.1 1.0 1 0 0 1 1 1 1 CDC45-like protein GCIP PF13324.6 RKP04005.1 - 6 6.4 6.6 11 5.5 6.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting zf-SNAP50_C PF12251.8 RKP04006.1 - 3.9e-35 121.4 0.0 6.1e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal TIMELESS PF04821.14 RKP04007.1 - 2.3e-22 79.6 0.7 2.5e-22 79.4 0.7 1.0 1 0 0 1 1 1 1 Timeless protein DRIM PF07539.12 RKP04007.1 - 0.015 13.6 0.1 0.018 13.4 0.1 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis GSH_synth_ATP PF03917.17 RKP04008.1 - 7.6e-110 367.2 0.0 8.7e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 RKP04008.1 - 2e-32 111.7 0.0 3.4e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase BHD_3 PF10405.9 RKP04009.1 - 2.8e-21 75.7 0.2 5.2e-21 74.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 RKP04009.1 - 9.6e-21 74.0 0.0 1.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 RKP04009.1 - 8.1e-15 55.5 0.7 2.8e-14 53.8 0.7 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 RKP04009.1 - 5e-14 51.9 0.0 5.5e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 RKP04009.1 - 0.0039 17.6 0.3 0.0039 17.6 0.3 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily zinc_ribbon_16 PF17034.5 RKP04010.1 - 2.4e-12 47.1 15.0 5.2e-11 42.8 7.9 2.7 3 0 0 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 RKP04010.1 - 0.0061 16.2 11.5 0.0061 16.2 11.5 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF5092 PF17010.5 RKP04011.1 - 2.6e-21 76.2 0.0 1.6e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5092) BatA PF07584.11 RKP04011.1 - 0.063 13.6 0.2 0.19 12.1 0.2 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Corona_nucleoca PF00937.18 RKP04014.1 - 3.1 6.8 4.2 4.4 6.2 2.5 1.9 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Peptidase_M24 PF00557.24 RKP04015.1 - 1.2e-51 175.4 0.0 1.9e-51 174.7 0.0 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RKP04015.1 - 4.7e-18 65.1 0.0 9.4e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 RKP04016.1 - 2.6e-54 184.1 0.1 3.5e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 RKP04016.1 - 2.7e-17 62.6 0.0 5e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain VanZ PF04892.12 RKP04017.1 - 7.6e-07 29.8 0.3 1e-06 29.4 0.3 1.1 1 0 0 1 1 1 1 VanZ like family CAF1 PF04857.20 RKP04018.1 - 3.3e-55 187.5 0.0 2.3e-27 96.0 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease zf_CCCH_4 PF18345.1 RKP04018.1 - 0.02 15.0 3.8 0.02 15.0 3.8 2.0 2 0 0 2 2 2 0 Zinc finger domain DNA_pol_A_exo1 PF01612.20 RKP04018.1 - 0.028 14.2 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease zf-CCCH PF00642.24 RKP04018.1 - 1.5 8.9 8.9 0.06 13.3 2.5 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBS PF00571.28 RKP04019.1 - 6e-19 68.2 11.3 0.00035 20.9 0.0 5.9 6 0 0 6 6 6 4 CBS domain ATPgrasp_N PF18130.1 RKP04019.1 - 0.12 12.9 4.3 19 5.9 0.0 3.5 3 0 0 3 3 3 0 ATP-grasp N-terminal domain ATPase PF06745.13 RKP04019.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiC Chitin_synth_2 PF03142.15 RKP04020.1 - 6.9e-231 767.4 0.0 1e-230 766.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 RKP04020.1 - 5.1e-98 329.1 0.0 8.4e-98 328.3 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 RKP04020.1 - 9.7e-16 57.4 0.0 2.4e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 RKP04020.1 - 2.1e-13 50.7 3.7 5.2e-13 49.3 3.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKP04020.1 - 1.2e-12 48.3 0.0 8.5e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RKP04020.1 - 1.4e-05 25.0 0.0 0.0037 17.1 0.0 3.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RKP04020.1 - 3.7e-05 23.3 0.0 0.00077 19.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 RKP04020.1 - 9.6e-05 22.5 0.3 0.56 10.4 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Nop25 PF09805.9 RKP04021.1 - 3.8e-09 37.1 11.6 1e-07 32.5 11.6 2.3 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) DNA_pol_phi PF04931.13 RKP04021.1 - 5.4 5.0 8.0 8.1 4.4 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bac_small_YrzI PF09501.10 RKP04021.1 - 6.2 7.0 5.1 11 6.2 5.1 1.4 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) MAT1 PF06391.13 RKP04022.1 - 2.3e-21 76.6 0.8 2.6e-21 76.4 0.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 RKP04022.1 - 5.9e-20 70.9 6.9 8.4e-20 70.4 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP04022.1 - 7.1e-06 25.8 8.7 1.4e-05 24.8 8.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP04022.1 - 7.6e-06 25.7 9.3 0.00015 21.5 10.8 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKP04022.1 - 9.6e-06 25.4 7.3 1.9e-05 24.4 7.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKP04022.1 - 1.3e-05 25.5 7.6 2e-05 24.9 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RKP04022.1 - 1.4e-05 24.9 8.2 0.00023 21.1 9.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 RKP04022.1 - 4.7e-05 23.1 5.3 0.00054 19.7 2.5 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 RKP04022.1 - 0.00069 19.6 9.5 0.0012 18.9 9.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RKP04022.1 - 0.0022 17.8 10.7 0.15 11.9 11.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DUF3797 PF12677.7 RKP04022.1 - 0.0085 16.0 0.8 0.0085 16.0 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3797) Zn_Tnp_IS1 PF03811.13 RKP04022.1 - 0.031 14.0 2.4 4.7 7.0 0.1 2.4 2 0 0 2 2 2 0 InsA N-terminal domain zf-RING_6 PF14835.6 RKP04022.1 - 0.64 9.9 4.4 5.5 6.9 1.5 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein HypA PF01155.19 RKP04022.1 - 1.1 9.3 4.4 10 6.2 4.9 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Opy2 PF09463.10 RKP04022.1 - 1.7 9.0 9.7 3.9 7.9 0.6 2.8 3 0 0 3 3 3 0 Opy2 protein GAGA PF09237.11 RKP04022.1 - 2.7 7.9 6.2 13 5.7 1.3 3.0 3 0 0 3 3 3 0 GAGA factor zf-C3HC4_4 PF15227.6 RKP04022.1 - 3.4 7.9 10.5 31 4.9 10.9 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RRN7 PF11781.8 RKP04022.1 - 3.5 7.4 6.6 19 5.1 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 NT-C2 PF10358.9 RKP04023.1 - 6.7e-25 87.5 0.0 8.2e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins IMS PF00817.20 RKP04024.1 - 2.2e-41 141.3 0.0 4e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RKP04024.1 - 8.6e-14 52.3 1.6 4.6e-13 49.9 0.6 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 RKP04024.1 - 0.00014 22.0 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif CK_II_beta PF01214.18 RKP04025.1 - 4.5e-67 225.4 0.0 5.3e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RRM_2 PF04059.12 RKP04027.1 - 4.6e-41 139.0 0.2 6.7e-41 138.4 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 BRAP2 PF07576.12 RKP04027.1 - 0.018 15.3 0.1 0.032 14.5 0.1 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 EIF4E-T PF10477.9 RKP04027.1 - 0.16 10.7 18.7 0.23 10.2 18.7 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RRM_1 PF00076.22 RKP04027.1 - 0.21 11.4 0.1 0.41 10.5 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPSF100_C PF13299.6 RKP04027.1 - 0.26 11.5 3.9 0.67 10.1 3.9 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 RKP04027.1 - 1.6 8.6 30.1 0.019 15.0 19.7 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 RKP04027.1 - 3.9 7.5 7.0 6.6 6.8 7.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4770 PF15994.5 RKP04027.1 - 4 7.6 12.3 6.7 6.9 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Borrelia_P83 PF05262.11 RKP04027.1 - 6.3 5.2 7.4 9.1 4.6 7.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Band_3_cyto PF07565.13 RKP04027.1 - 6.4 6.5 9.1 12 5.6 9.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TB2_DP1_HVA22 PF03134.19 RKP04028.1 - 5.8e-30 103.0 3.6 5.8e-30 103.0 3.6 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 RKP04028.1 - 0.16 12.2 3.5 2.8 8.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) HMMR_C PF15908.5 RKP04030.1 - 0.052 13.8 0.3 0.052 13.8 0.3 2.6 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal HALZ PF02183.18 RKP04030.1 - 3.7 7.9 7.0 41 4.5 0.0 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper Pkinase PF00069.25 RKP04031.1 - 2.1e-46 158.4 0.0 5.4e-46 157.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP04031.1 - 7.2e-19 68.1 0.0 2.7e-17 62.9 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 RKP04031.1 - 0.038 13.6 0.2 0.16 11.5 0.0 1.9 1 1 1 2 2 2 0 RIO1 family RNA_pol_A_bac PF01000.26 RKP04032.1 - 3.7e-33 114.2 0.0 9.9e-33 112.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 RKP04032.1 - 2.3e-17 62.2 0.0 3.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.29 RKP04033.1 - 4.7e-36 124.2 0.0 1.3e-34 119.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP04033.1 - 8.6e-31 106.6 0.0 1.7e-29 102.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP04033.1 - 0.00019 21.5 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 RKP04033.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain PIN_10 PF18478.1 RKP04033.1 - 0.058 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 PIN like domain UTP25 PF06862.12 RKP04033.1 - 0.069 11.9 1.0 0.32 9.7 0.1 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 RKP04033.1 - 0.095 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Terminase_6 PF03237.15 RKP04033.1 - 0.16 11.6 0.0 3.4 7.3 0.0 2.4 2 1 0 2 2 2 0 Terminase-like family CTP_transf_1 PF01148.20 RKP04034.1 - 7.6e-05 22.6 0.8 9.3e-05 22.3 0.8 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Clat_adaptor_s PF01217.20 RKP04035.1 - 3.7e-19 69.1 0.1 4.5e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Tim54 PF11711.8 RKP04036.1 - 6.5e-31 107.5 0.0 7.1e-30 104.0 0.0 2.5 1 1 1 2 2 2 1 Inner membrane protein import complex subunit Tim54 PEMT PF04191.13 RKP04037.1 - 1.9e-41 140.8 12.6 1.7e-27 95.9 1.0 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 RKP04037.1 - 0.031 14.8 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 SKICH domain DWNN PF08783.11 RKP04038.1 - 1.9e-27 95.4 0.2 3.3e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 RKP04038.1 - 7.1e-10 38.5 3.4 1.3e-09 37.7 3.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 RKP04038.1 - 0.00019 21.2 3.8 0.00019 21.2 3.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 RKP04038.1 - 0.0049 16.9 1.4 0.0087 16.1 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.6 RKP04038.1 - 0.01 16.2 4.1 0.01 16.2 4.1 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 RKP04038.1 - 0.018 14.9 4.5 0.018 14.9 4.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.6 RKP04038.1 - 0.075 13.0 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_3 PF13920.6 RKP04038.1 - 0.72 9.8 10.9 0.044 13.6 4.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP04038.1 - 2 8.5 9.6 0.24 11.5 4.9 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RKP04038.1 - 3.2 8.0 11.0 0.24 11.6 5.9 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.29 RKP04039.1 - 2.3e-08 33.8 6.9 4.2e-08 33.0 6.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKP04039.1 - 0.17 11.4 4.3 0.33 10.5 4.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 RKP04039.1 - 0.27 11.3 1.2 0.62 10.1 1.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Pyr_redox_2 PF07992.14 RKP04040.1 - 8e-48 163.2 0.0 9.4e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKP04040.1 - 1.2e-16 60.9 0.0 2.1e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKP04040.1 - 5.6e-15 55.7 0.0 5.7e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 RKP04040.1 - 0.00035 19.9 0.1 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 RKP04040.1 - 0.0034 17.8 0.1 0.31 11.5 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 RKP04040.1 - 0.0056 15.8 1.5 0.86 8.6 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 RKP04040.1 - 0.063 12.4 0.0 0.91 8.6 0.0 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 RKP04040.1 - 0.11 11.3 1.9 0.88 8.3 0.2 2.4 2 1 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 RKP04040.1 - 0.35 11.1 2.6 0.42 10.9 0.3 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF2890 PF11081.8 RKP04041.1 - 0.27 11.4 2.9 1.3 9.1 2.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) MFS_1 PF07690.16 RKP04043.1 - 4.4e-33 114.7 48.7 5e-24 84.9 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 RKP04043.1 - 6.8e-08 32.2 26.5 9.1e-08 31.8 26.5 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF5337 PF17272.2 RKP04043.1 - 0.2 11.5 6.2 5 7.0 2.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Pho88 PF10032.9 RKP04044.1 - 8.3e-52 175.1 0.1 9.1e-52 175.0 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ribosomal_L30 PF00327.20 RKP04045.1 - 2.2e-12 46.6 0.1 2.4e-12 46.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L7Ae PF01248.26 RKP04046.1 - 2.3e-20 72.1 0.4 4.1e-20 71.3 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PMSR PF01625.21 RKP04047.1 - 8.5e-60 201.4 0.5 9.9e-60 201.1 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GshA PF08886.11 RKP04047.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Glycos_transf_1 PF00534.20 RKP04048.1 - 2.8e-10 40.0 0.0 5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RKP04048.1 - 1.1e-08 35.6 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 RKP04048.1 - 7.8e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) TFIIE_alpha PF02002.17 RKP04050.1 - 4.7e-14 52.1 0.0 6.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 RKP04050.1 - 0.021 14.9 0.1 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF4788 PF16032.5 RKP04050.1 - 0.027 13.4 0.3 0.055 12.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4788) Podoplanin PF05808.11 RKP04051.1 - 0.18 11.9 7.8 0.29 11.2 7.8 1.4 1 1 0 1 1 1 0 Podoplanin MID_MedPIWI PF18296.1 RKP04051.1 - 0.65 9.7 5.7 0.79 9.5 5.7 1.1 1 0 0 1 1 1 0 MID domain of medPIWI Menin PF05053.13 RKP04051.1 - 3.7 5.8 7.8 4 5.7 7.8 1.0 1 0 0 1 1 1 0 Menin Epimerase PF01370.21 RKP04053.1 - 4.1e-42 144.3 0.0 5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RKP04053.1 - 6.5e-34 117.8 0.0 7.8e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 RKP04053.1 - 6.6e-11 42.4 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 RKP04053.1 - 1.5e-10 40.7 0.0 1.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RKP04053.1 - 1.3e-09 37.5 0.0 6.8e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RKP04053.1 - 7.5e-08 31.8 0.0 1.8e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 RKP04053.1 - 5.1e-07 29.8 0.0 8.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 RKP04053.1 - 0.0023 17.6 0.0 0.0041 16.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 RKP04053.1 - 0.0048 16.0 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 RKP04053.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase mRNA_cap_enzyme PF01331.19 RKP04054.1 - 1.6e-26 93.4 0.4 7.1e-15 55.4 0.1 2.2 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 RKP04054.1 - 4e-17 62.8 0.2 6.8e-17 62.1 0.2 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 RKP04054.1 - 9e-07 28.7 0.0 0.00037 20.2 0.0 2.5 1 1 0 2 2 2 2 ATP dependent DNA ligase domain HhH-GPD PF00730.25 RKP04055.1 - 6.2e-17 62.0 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RKP04055.1 - 6.8e-06 25.7 0.1 1.4e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 RKP04055.1 - 3.5e-05 24.0 7.4 3.5e-05 24.0 7.4 1.8 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III zf-RING_2 PF13639.6 RKP04056.1 - 8.2e-11 42.1 3.1 1.5e-10 41.2 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RKP04056.1 - 1.4e-08 34.3 1.4 2.7e-08 33.4 1.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 RKP04056.1 - 2.2e-08 33.8 1.1 3.6e-08 33.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP04056.1 - 1.4e-07 31.2 3.1 2.7e-07 30.3 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 RKP04056.1 - 5.1e-06 26.7 5.0 1.5e-05 25.2 5.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKP04056.1 - 2.3e-05 24.2 2.3 3.8e-05 23.6 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RKP04056.1 - 8.2e-05 22.6 0.8 0.00016 21.6 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 RKP04056.1 - 0.00027 20.9 1.0 0.00053 20.0 1.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 RKP04056.1 - 0.00087 19.4 1.8 0.0017 18.5 1.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RKP04056.1 - 0.0078 15.8 3.1 0.018 14.7 3.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 RKP04056.1 - 0.011 15.9 3.1 0.019 15.1 3.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 RKP04056.1 - 0.035 14.0 1.5 0.061 13.2 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2070 PF09843.9 RKP04056.1 - 0.31 9.3 5.3 0.43 8.8 5.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PHD PF00628.29 RKP04056.1 - 0.67 9.9 3.2 1.1 9.2 3.2 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 RKP04056.1 - 1.1 9.4 2.9 2.1 8.5 2.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RKP04056.1 - 2 8.3 4.9 1.6 8.7 2.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.32 RKP04057.1 - 1e-12 48.3 0.2 0.048 14.6 0.5 5.7 4 2 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP04057.1 - 0.0049 17.1 0.0 3.7 7.9 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FH2 PF02181.23 RKP04058.1 - 1.3e-49 169.3 5.0 1.3e-49 169.3 5.0 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 RKP04058.1 - 4e-15 56.0 0.0 8.3e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 RKP04058.1 - 0.00059 19.4 0.5 0.0018 17.9 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FUSC_2 PF13515.6 RKP04059.1 - 8.5e-17 61.5 16.0 8.5e-17 61.5 16.0 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 RKP04059.1 - 1.3e-08 34.1 8.9 1.3e-08 34.1 8.9 1.5 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 RKP04059.1 - 9.7e-06 25.6 2.6 1.6e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 DUF1118 PF06549.12 RKP04059.1 - 1.2 9.5 4.4 33 4.8 0.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1118) SecY PF00344.20 RKP04060.1 - 1.3e-72 244.7 9.9 1.9e-72 244.2 9.9 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 RKP04060.1 - 8.5e-19 67.1 2.0 1.2e-18 66.6 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p DEAD PF00270.29 RKP04061.1 - 6.6e-49 166.0 0.0 3.3e-48 163.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP04061.1 - 2.4e-32 111.5 0.0 6.7e-32 110.1 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKP04061.1 - 0.0019 18.3 0.0 0.0088 16.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKP04061.1 - 0.022 15.1 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain UTP25 PF06862.12 RKP04061.1 - 0.041 12.7 0.0 0.6 8.8 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 tRNA-synt_1 PF00133.22 RKP04062.1 - 3.3e-216 719.2 0.1 1.1e-215 717.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RKP04062.1 - 9.1e-21 74.4 1.1 1.8e-20 73.4 0.1 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RKP04062.1 - 1.4e-07 30.6 1.4 0.24 10.1 0.1 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) T-box PF00907.22 RKP04063.1 - 6.4e-45 153.7 0.0 9.4e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 T-box Methyltr_RsmB-F PF01189.17 RKP04065.1 - 2.2e-37 128.6 0.0 3.4e-36 124.8 0.0 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RKP04065.1 - 0.0044 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase HEAT PF02985.22 RKP04066.1 - 4.3e-10 39.0 0.3 0.081 13.2 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 RKP04066.1 - 2.6e-07 31.0 0.5 0.012 16.1 0.0 5.5 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 RKP04066.1 - 1.8e-06 28.1 0.1 1.2e-05 25.4 0.1 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 RKP04066.1 - 7.9e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Vac14_Fab1_bd PF12755.7 RKP04066.1 - 4.5e-05 24.0 0.0 0.23 12.0 0.0 2.9 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 RKP04066.1 - 0.00016 22.0 0.4 0.073 13.5 0.0 3.5 2 1 3 5 5 5 2 HEAT repeats CLASP_N PF12348.8 RKP04066.1 - 0.0043 16.7 0.0 1.5 8.3 0.0 3.0 2 1 1 3 3 3 1 CLASP N terminal DUF3458 PF11940.8 RKP04066.1 - 0.032 14.7 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold Pkinase_Tyr PF07714.17 RKP04066.1 - 0.034 13.4 0.0 0.25 10.6 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Adaptin_N PF01602.20 RKP04066.1 - 0.17 10.4 0.1 0.28 9.7 0.1 1.4 1 0 0 1 1 1 0 Adaptin N terminal region DUF4392 PF14336.6 RKP04066.1 - 1.2 8.5 3.6 2.7 7.3 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) ATG27 PF09451.10 RKP04067.1 - 2.6e-29 102.9 0.0 8.7e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 RKP04067.1 - 0.00073 18.7 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 RKP04067.1 - 0.12 12.4 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat AAA_13 PF13166.6 RKP04067.1 - 1.9 7.1 32.4 0.5 9.0 8.8 2.1 1 1 1 2 2 2 0 AAA domain HOOK PF05622.12 RKP04067.1 - 3.1 5.8 38.5 1.6 6.8 7.6 2.4 1 1 1 2 2 2 0 HOOK protein Sec63 PF02889.16 RKP04068.1 - 3.7e-93 311.4 0.0 2.5e-57 194.0 0.1 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 RKP04068.1 - 5.2e-52 176.2 0.0 2.1e-27 96.0 0.2 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 RKP04068.1 - 2.6e-26 92.7 0.0 3.5e-12 46.7 0.0 2.9 3 0 0 3 3 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKP04068.1 - 1.2e-14 54.6 0.0 2.3e-05 24.7 0.0 4.1 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 RKP04068.1 - 1.6e-07 31.6 1.3 0.0041 17.4 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 RKP04068.1 - 0.00019 21.0 4.6 0.34 10.5 0.1 3.5 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 RKP04068.1 - 0.00039 20.8 2.4 0.052 13.9 0.3 3.0 3 0 0 3 3 2 1 AAA domain Helicase_PWI PF18149.1 RKP04068.1 - 0.0046 17.1 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain PhoH PF02562.16 RKP04068.1 - 0.015 14.8 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 RKP04068.1 - 0.086 11.9 0.0 7.7 5.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 RKP04068.1 - 0.088 12.5 1.4 13 5.5 0.0 4.1 5 0 0 5 5 5 0 IstB-like ATP binding protein DUF4168 PF13767.6 RKP04068.1 - 0.14 13.3 0.2 5.5 8.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Fer2 PF00111.27 RKP04069.1 - 2.6e-12 46.5 0.1 3.7e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain EF_TS PF00889.19 RKP04070.1 - 1.7e-15 57.2 0.6 4.1e-13 49.4 1.1 3.4 1 1 1 2 2 2 1 Elongation factor TS Voltage_CLC PF00654.20 RKP04071.1 - 8e-91 304.9 32.5 8e-91 304.9 32.5 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 RKP04071.1 - 1.2e-05 25.7 0.0 3.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 CBS domain PTPS PF01242.19 RKP04073.1 - 8.6e-24 83.9 0.0 9.7e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Nuf2 PF03800.14 RKP04074.1 - 2.6e-39 134.5 0.1 1.7e-37 128.7 0.0 2.5 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 RKP04074.1 - 5.1e-11 42.7 15.6 5.1e-11 42.7 15.6 4.5 2 2 2 4 4 3 2 Designed helical repeat protein 10 domain DUF1664 PF07889.12 RKP04074.1 - 0.0085 16.1 17.9 0.03 14.4 1.2 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF1664) APG6_N PF17675.1 RKP04074.1 - 0.015 15.8 45.9 0.068 13.7 4.9 4.4 1 1 3 4 4 4 0 Apg6 coiled-coil region ApoO PF09769.9 RKP04074.1 - 0.028 14.4 5.4 0.16 11.9 0.4 3.4 3 0 0 3 3 3 0 Apolipoprotein O APG6 PF04111.12 RKP04074.1 - 0.079 12.9 1.6 6.4 6.7 0.1 2.3 1 1 0 2 2 2 0 Apg6 BARA domain Spc7 PF08317.11 RKP04074.1 - 0.14 11.0 37.8 0.024 13.5 7.8 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein FapA PF03961.13 RKP04074.1 - 0.18 10.4 17.7 0.73 8.4 0.1 3.3 1 1 1 3 3 3 0 Flagellar Assembly Protein A GAS PF13851.6 RKP04074.1 - 0.74 9.1 33.0 0.093 12.1 0.4 4.1 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 RKP04074.1 - 0.92 9.5 28.5 1.1 9.3 8.4 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 RKP04074.1 - 1 9.6 18.7 1.1 9.4 0.6 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.11 RKP04074.1 - 1.2 9.4 5.5 4 7.7 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1319) Med30 PF11315.8 RKP04074.1 - 2.9 8.1 17.6 0.39 10.9 0.6 3.8 1 1 3 4 4 4 0 Mediator complex subunit 30 Jnk-SapK_ap_N PF09744.9 RKP04074.1 - 3 8.1 33.2 5.7 7.2 8.5 3.7 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Lectin_N PF03954.14 RKP04074.1 - 7.2 6.4 19.6 3.3 7.4 0.5 4.1 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain ATG16 PF08614.11 RKP04074.1 - 8.2 6.6 52.6 4.1 7.6 14.1 3.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Occludin_ELL PF07303.13 RKP04074.1 - 8.9 7.1 13.2 0.5 11.1 0.7 4.1 1 1 2 4 4 4 0 Occludin homology domain DEAD PF00270.29 RKP04075.1 - 1.4e-48 164.9 0.0 5.1e-48 163.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKP04075.1 - 7.9e-28 97.0 0.0 2e-26 92.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WD40 PF00400.32 RKP04076.1 - 2.2e-07 31.4 3.2 0.75 10.8 0.1 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat HEAT_EZ PF13513.6 RKP04077.1 - 9.6e-26 89.8 20.3 6.1e-09 36.2 0.0 12.4 11 1 2 13 13 12 4 HEAT-like repeat HEAT PF02985.22 RKP04077.1 - 5.2e-20 69.8 20.2 0.0026 17.9 0.0 12.1 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.6 RKP04077.1 - 6.4e-17 61.7 5.7 0.0053 17.1 0.0 8.3 4 4 3 8 8 8 5 HEAT repeats Cnd1 PF12717.7 RKP04077.1 - 3.9e-12 46.5 6.1 7.4e-05 22.8 0.0 5.4 3 2 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 RKP04077.1 - 7.1e-11 42.6 0.4 0.098 13.3 0.2 6.2 4 1 4 8 8 7 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 RKP04077.1 - 1.8e-08 34.2 0.1 9.1e-08 31.9 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 RKP04077.1 - 2.7e-08 32.8 15.0 0.0012 17.4 0.1 5.3 3 2 1 4 4 4 3 Adaptin N terminal region Arm PF00514.23 RKP04077.1 - 8.3e-07 28.8 6.9 2.5 8.2 0.0 7.1 6 1 0 6 6 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 RKP04077.1 - 1.7e-05 24.5 0.8 3.2 7.2 0.0 5.4 6 1 1 7 7 7 1 CLASP N terminal DUF3437 PF11919.8 RKP04077.1 - 6.2e-05 22.8 0.9 8.2 6.4 0.0 4.8 5 0 0 5 5 3 1 Domain of unknown function (DUF3437) Nipped-B_C PF12830.7 RKP04077.1 - 0.0017 18.3 0.3 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Tti2 PF10521.9 RKP04077.1 - 0.011 15.3 0.0 1.6 8.2 0.0 3.7 4 0 0 4 4 4 0 Tti2 family ANAPC15 PF15243.6 RKP04077.1 - 0.013 15.9 1.0 0.03 14.7 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 ParcG PF10274.9 RKP04077.1 - 0.078 13.1 0.2 19 5.3 0.0 4.1 4 1 0 4 4 4 0 Parkin co-regulated protein Xpo1 PF08389.12 RKP04077.1 - 0.1 12.6 0.9 6.5 6.8 0.0 4.0 4 1 2 6 6 6 0 Exportin 1-like protein MMS19_N PF14500.6 RKP04077.1 - 0.11 12.0 1.2 11 5.5 0.3 3.5 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RasGEF_N_2 PF14663.6 RKP04077.1 - 0.12 12.8 1.1 9.3 6.7 0.1 4.1 4 1 1 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMS19_C PF12460.8 RKP04077.1 - 1.5 7.8 7.5 8.6 5.4 1.8 3.4 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal PQ-loop PF04193.14 RKP04078.1 - 1.2e-22 79.4 0.5 6.2e-11 41.9 0.0 2.5 2 1 0 2 2 2 2 PQ loop repeat tRNA-synt_His PF13393.6 RKP04079.1 - 4.7e-43 147.6 1.4 2.5e-42 145.2 0.0 2.0 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 RKP04079.1 - 1.7e-07 31.3 0.0 4.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 RKP04079.1 - 0.00079 19.4 0.0 0.0088 16.0 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 RKP04079.1 - 0.015 14.4 0.0 0.42 9.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) PDEase_I PF00233.19 RKP04080.1 - 1.7e-66 224.3 0.0 2e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MRP-S25 PF13741.6 RKP04081.1 - 4.1e-18 65.8 3.2 1.2e-12 47.9 0.2 2.5 2 0 0 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 RKP04081.1 - 0.0017 18.6 0.3 0.057 13.7 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal protein S23 Rxt3 PF08642.10 RKP04083.1 - 1.8e-20 74.0 0.0 4.8e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 RKP04083.1 - 0.028 14.5 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 LCCL domain Snapin_Pallidin PF14712.6 RKP04084.1 - 0.0003 21.1 0.8 0.1 13.0 0.8 2.1 1 1 0 1 1 1 1 Snapin/Pallidin DUF4140 PF13600.6 RKP04084.1 - 0.55 10.7 4.9 5.2 7.6 3.9 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 RKP04084.1 - 0.85 10.0 3.4 21 5.5 0.1 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FbpA PF05833.11 RKP04085.1 - 7.2e-38 130.5 0.2 5e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 RKP04085.1 - 1.8e-17 63.2 0.1 5.8e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 RKP04085.1 - 3.4e-10 40.5 0.1 6e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF1759 PF03564.15 RKP04085.1 - 0.16 11.9 0.2 0.29 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) SDA1 PF05285.12 RKP04086.1 - 0.27 10.6 4.8 0.51 9.7 4.8 1.4 1 0 0 1 1 1 0 SDA1 Rotamase_3 PF13616.6 RKP04087.1 - 2.1e-18 67.0 0.2 9.5e-18 64.8 0.2 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 RKP04087.1 - 2.4e-14 54.0 0.0 4.7e-14 53.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 RKP04087.1 - 0.00061 20.6 0.0 0.00082 20.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DAGK_acc PF00609.19 RKP04089.1 - 1.9e-13 51.0 0.0 2.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RKP04089.1 - 2.3e-13 49.9 0.0 4.4e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Septin PF00735.18 RKP04090.1 - 6.2e-102 340.7 0.0 7.5e-102 340.4 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RKP04090.1 - 3.6e-08 33.5 0.0 8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKP04090.1 - 0.00015 21.7 0.0 0.00048 20.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 RKP04090.1 - 0.00031 20.1 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 RKP04090.1 - 0.00034 20.1 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 RKP04090.1 - 0.00036 20.8 0.0 0.00085 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP04090.1 - 0.00049 20.5 0.2 0.00098 19.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 RKP04090.1 - 0.0038 16.4 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 RKP04090.1 - 0.006 16.1 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 RKP04090.1 - 0.0063 16.1 0.0 0.025 14.2 0.0 2.0 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.27 RKP04090.1 - 0.0063 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 RKP04090.1 - 0.011 15.8 0.4 1.7 8.7 0.2 2.3 1 1 1 2 2 2 0 Dynamin family NB-ARC PF00931.22 RKP04090.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 RKP04090.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 RKP04090.1 - 0.04 14.2 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 RKP04090.1 - 0.05 12.7 0.1 0.56 9.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein G-alpha PF00503.20 RKP04090.1 - 0.057 12.6 0.3 3.5 6.7 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 RKP04090.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Sdh5 PF03937.16 RKP04091.1 - 2.2e-28 98.0 0.2 2.8e-28 97.7 0.2 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Autophagy_N PF03986.13 RKP04092.1 - 1.5e-41 141.6 0.0 2.8e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 RKP04092.1 - 5.3e-20 71.7 0.9 9.8e-20 70.9 0.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 RKP04092.1 - 1.3e-15 56.5 1.9 3e-15 55.4 1.9 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal TFIID_20kDa PF03847.13 RKP04093.1 - 5.9e-15 55.5 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 RKP04093.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.3 3 0 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit Ank_5 PF13857.6 RKP04095.1 - 0.00075 19.8 0.4 0.0023 18.2 0.4 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 RKP04095.1 - 0.039 14.4 0.3 0.12 12.9 0.3 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 RKP04095.1 - 0.13 12.9 0.1 0.4 11.4 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat TMF_TATA_bd PF12325.8 RKP04096.1 - 0.003 17.8 9.2 0.003 17.8 9.2 9.6 6 2 4 11 11 11 3 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 RKP04096.1 - 0.0059 17.1 93.6 0.046 14.2 0.0 8.6 5 2 1 8 8 8 5 Fez1 CENP-F_leu_zip PF10473.9 RKP04096.1 - 0.11 12.5 85.7 0.013 15.5 4.3 9.0 5 1 4 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC92 PF14916.6 RKP04096.1 - 0.56 10.0 0.0 0.56 10.0 0.0 3.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Cyt-b5 PF00173.28 RKP04097.1 - 6.7e-19 67.8 0.0 1.4e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 RKP04097.1 - 2.2e-11 44.2 15.7 2.2e-11 44.2 15.7 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 RKP04097.1 - 0.021 15.0 0.1 0.038 14.2 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Glyco_hydro_35 PF01301.19 RKP04098.1 - 5e-09 36.2 0.0 5.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 ThiF PF00899.21 RKP04099.1 - 4.2e-63 213.0 0.1 5.2e-63 212.7 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 RKP04099.1 - 1.4e-07 31.7 0.0 4.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 RKP04099.1 - 0.013 15.5 0.0 0.05 13.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 RKP04099.1 - 0.03 14.9 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 RKP04099.1 - 0.037 14.5 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 RKP04099.1 - 0.069 13.4 0.4 0.38 11.0 0.4 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RasGEF PF00617.19 RKP04100.1 - 5.1e-13 49.6 0.0 5.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain Inhibitor_I10 PF12559.8 RKP04100.1 - 0.036 14.3 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine endopeptidase inhibitors NYD-SP28_assoc PF14775.6 RKP04102.1 - 0.0047 17.0 0.4 0.0061 16.6 0.4 1.2 1 0 0 1 1 1 1 Sperm tail C-terminal domain ETC_C1_NDUFA4 PF04800.12 RKP04103.1 - 4.1e-36 123.1 0.8 4.7e-36 122.9 0.8 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 RKP04103.1 - 0.042 14.0 0.1 0.092 12.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2280 PF10045.9 RKP04103.1 - 0.057 13.7 0.1 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Cu_amine_oxidN2 PF02727.16 RKP04103.1 - 0.14 12.4 0.1 0.42 10.9 0.0 1.8 2 1 0 2 2 2 0 Copper amine oxidase, N2 domain HEAT_2 PF13646.6 RKP04104.1 - 3e-33 114.1 0.5 2.5e-17 63.1 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 RKP04104.1 - 5e-28 94.9 0.3 6.2e-07 29.5 0.0 6.6 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.22 RKP04104.1 - 1.6e-14 52.8 0.7 0.016 15.4 0.0 5.1 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 RKP04104.1 - 1.2e-10 41.6 1.3 0.29 11.7 0.0 5.0 5 0 0 5 5 5 3 HEAT-like repeat Arm PF00514.23 RKP04104.1 - 1.1e-05 25.3 0.2 0.47 10.6 0.0 3.9 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 RKP04104.1 - 0.001 19.1 0.0 5.3 7.1 0.0 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 RKP04104.1 - 0.0022 18.3 0.2 1.2 9.5 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Vitellogenin_N PF01347.22 RKP04104.1 - 0.11 10.8 0.0 4.1 5.7 0.0 2.6 2 1 1 3 3 3 0 Lipoprotein amino terminal region Pex2_Pex12 PF04757.14 RKP04105.1 - 7e-21 74.9 9.2 1.6e-20 73.7 9.2 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 RKP04105.1 - 2.9e-05 23.9 5.2 4.7e-05 23.3 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RKP04105.1 - 6.6e-05 23.2 6.2 0.00011 22.4 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RKP04105.1 - 0.0001 22.1 6.3 0.00016 21.4 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKP04105.1 - 0.00011 22.0 6.7 0.00018 21.3 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKP04105.1 - 0.00051 20.0 5.8 0.001 19.0 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RKP04105.1 - 0.00073 19.3 5.9 0.0016 18.3 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKP04105.1 - 0.0011 19.1 7.7 0.0034 17.5 7.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 RKP04105.1 - 0.25 11.1 2.9 0.5 10.2 2.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 RKP04105.1 - 0.29 11.4 2.7 0.56 10.5 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Urm1 PF09138.11 RKP04106.1 - 3.9e-32 110.5 0.0 4.6e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 RKP04106.1 - 0.00026 21.5 0.0 0.00037 21.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family Gemini_AC4_5_2 PF08464.10 RKP04107.1 - 0.017 15.1 1.1 0.042 13.8 1.1 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region NOG1 PF06858.14 RKP04107.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Peptidase_M49 PF03571.15 RKP04108.1 - 1.2e-196 654.4 0.0 1.4e-196 654.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 PP28 PF10252.9 RKP04109.1 - 2e-20 73.0 14.6 3.2e-20 72.4 13.9 1.7 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 AF-4 PF05110.13 RKP04109.1 - 0.055 11.6 10.6 0.074 11.1 10.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop53 PF07767.11 RKP04109.1 - 7.2 5.9 18.3 7.4 5.8 18.1 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SCP2 PF02036.17 RKP04110.1 - 4.1e-05 24.0 0.0 5.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 SCP-2 sterol transfer family ARPC4 PF05856.12 RKP04111.1 - 1.9e-80 268.3 5.7 2.1e-80 268.2 5.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF4255 PF14065.6 RKP04111.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) GPS2_interact PF15784.5 RKP04111.1 - 0.076 13.5 0.9 14 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Barwin PF00967.17 RKP04112.1 - 0.07 13.0 0.5 0.24 11.3 0.4 1.9 1 1 0 1 1 1 0 Barwin family SWI-SNF_Ssr4 PF08549.10 RKP04112.1 - 0.26 9.9 7.9 0.34 9.5 7.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) NDK PF00334.19 RKP04113.1 - 8.6e-23 80.8 0.0 5.3e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase RRM_1 PF00076.22 RKP04114.1 - 1.9e-47 159.0 1.0 1e-21 76.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKP04114.1 - 3.4e-07 30.0 0.0 0.012 15.4 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 RKP04114.1 - 0.00016 21.6 0.0 4.5 7.4 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 RKP04114.1 - 0.002 18.2 0.1 1.7 8.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RBM39linker PF15519.6 RKP04114.1 - 0.028 15.5 0.1 0.1 13.7 0.1 1.9 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Coilin_N PF15862.5 RKP04115.1 - 0.00085 19.1 0.0 0.0066 16.3 0.0 2.5 2 1 0 2 2 2 1 Coilin N-terminus Macoilin PF09726.9 RKP04116.1 - 0.038 12.6 19.1 0.054 12.1 19.1 1.1 1 0 0 1 1 1 0 Macoilin family GreA_GreB_N PF03449.15 RKP04116.1 - 0.25 11.5 0.1 0.25 11.5 0.1 3.5 3 1 0 3 3 3 0 Transcription elongation factor, N-terminal Spc7 PF08317.11 RKP04116.1 - 0.41 9.5 27.0 0.091 11.6 20.5 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 RKP04116.1 - 0.42 10.7 17.8 0.72 9.9 4.5 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 RKP04116.1 - 0.61 10.1 25.6 1.4 9.0 15.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 RKP04116.1 - 0.76 9.3 24.2 0.11 12.0 10.9 2.7 2 1 1 3 3 3 0 Intermediate filament protein TLV_coat PF00429.19 RKP04116.1 - 0.97 8.0 3.8 1.5 7.4 3.8 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Jnk-SapK_ap_N PF09744.9 RKP04116.1 - 7.4 6.8 27.5 0.7 10.1 12.7 2.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 RKP04116.1 - 8.7 4.1 9.1 3.2 5.6 6.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Cyclin_N PF00134.23 RKP04117.1 - 2.6e-18 66.0 5.8 4.2e-16 58.8 2.9 2.7 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 RKP04117.1 - 0.0003 20.8 4.0 0.012 15.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat ExoD PF06055.12 RKP04117.1 - 0.089 12.2 0.7 0.32 10.3 0.0 1.9 1 1 1 2 2 2 0 Exopolysaccharide synthesis, ExoD HSF_DNA-bind PF00447.17 RKP04119.1 - 6.9e-19 68.3 0.1 7.7e-19 68.1 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 RKP04119.1 - 0.0031 17.9 0.0 0.0036 17.7 0.0 1.2 1 0 0 1 1 1 1 Ets-domain RTC PF01137.21 RKP04120.1 - 1.3e-47 161.9 0.0 1.5e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 RKP04120.1 - 5e-32 110.5 0.0 8.3e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pkinase PF00069.25 RKP04121.1 - 1e-71 241.4 0.0 1.1e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP04121.1 - 1.9e-39 135.5 0.0 2.3e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP04121.1 - 2e-06 27.4 0.0 4.1e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP04121.1 - 0.0007 19.0 0.1 0.0018 17.6 0.1 1.6 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP04121.1 - 0.0026 17.7 0.0 0.044 13.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKP04121.1 - 0.0033 16.4 0.1 0.0044 16.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain MFS_1 PF07690.16 RKP04123.1 - 3e-25 88.9 26.9 1.5e-15 57.0 3.4 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RKP04123.1 - 1.5e-06 27.4 12.1 0.0013 17.7 0.6 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 RKP04123.1 - 0.00089 18.2 3.0 0.013 14.4 0.6 2.3 2 0 0 2 2 2 2 MFS_1 like family Herpes_UL73 PF03554.13 RKP04123.1 - 0.11 12.5 1.0 35 4.5 1.6 2.7 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Mito_fiss_reg PF05308.11 RKP04124.1 - 0.016 15.3 2.9 0.02 15.0 0.9 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4140 PF13600.6 RKP04124.1 - 0.19 12.2 1.8 6.5 7.3 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LPP PF04728.13 RKP04124.1 - 0.74 10.3 5.4 9.9 6.6 0.1 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper WPP PF13943.6 RKP04124.1 - 1.1 9.7 3.8 5.1 7.6 0.5 2.5 2 0 0 2 2 2 0 WPP domain CAP_N PF01213.19 RKP04124.1 - 1.2 8.5 12.0 0.077 12.5 6.9 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 RKP04124.1 - 1.3 9.0 12.3 3.1 7.9 12.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SMN PF06003.12 RKP04124.1 - 2 7.6 7.5 3.7 6.7 7.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-C2H2 PF00096.26 RKP04126.1 - 8.5e-10 38.6 10.0 3.3e-05 24.1 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP04126.1 - 2.2e-06 28.0 7.0 0.01 16.6 0.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKP04126.1 - 1e-05 25.7 0.2 1e-05 25.7 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain DUF4729 PF15866.5 RKP04126.1 - 0.039 13.3 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) zf-C2H2_8 PF15909.5 RKP04126.1 - 0.068 13.5 0.2 0.17 12.2 0.2 1.6 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 RKP04126.1 - 2.6 8.6 5.3 16 6.0 0.5 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type DUF1754 PF08555.10 RKP04127.1 - 4.5e-09 37.0 0.5 4.5e-09 37.0 0.5 1.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) GATA PF00320.27 RKP04128.1 - 1.8e-10 40.2 8.0 3.3e-10 39.4 8.0 1.5 1 0 0 1 1 1 1 GATA zinc finger Sec7 PF01369.20 RKP04129.1 - 1e-36 126.3 0.0 1.5e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 RKP04129.1 - 6.5e-06 26.5 0.0 2.1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain ArfGap PF01412.18 RKP04130.1 - 0.02 14.9 4.8 1 9.5 1.9 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf MBOAT_2 PF13813.6 RKP04131.1 - 5.1e-13 49.1 4.8 1.3e-12 47.8 4.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family YIF1 PF03878.15 RKP04132.1 - 3.6e-76 255.8 1.2 4.3e-76 255.6 1.2 1.0 1 0 0 1 1 1 1 YIF1 Annexin PF00191.20 RKP04133.1 - 5.6e-78 257.0 0.2 1.7e-22 79.3 0.1 4.1 4 0 0 4 4 4 4 Annexin Homeodomain PF00046.29 RKP04134.1 - 1.3e-13 50.5 1.3 2.2e-13 49.8 1.3 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 RKP04134.1 - 0.0072 15.8 0.1 0.024 14.1 0.1 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 RKP04134.1 - 0.024 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Cytochrom_C_2 PF01322.20 RKP04134.1 - 0.13 13.2 0.5 0.24 12.3 0.5 1.3 1 0 0 1 1 1 0 Cytochrome C' PPR_2 PF13041.6 RKP04135.1 - 8.2e-05 22.7 0.3 0.0021 18.2 0.0 3.1 3 1 1 4 4 4 2 PPR repeat family PPR_long PF17177.4 RKP04135.1 - 0.001 18.5 0.4 0.0035 16.7 0.4 1.9 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 RKP04135.1 - 0.0083 16.3 0.0 0.13 12.5 0.0 3.1 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 RKP04135.1 - 0.068 13.3 0.0 0.5 10.5 0.0 2.4 1 1 1 2 2 2 0 Pentatricopeptide repeat domain DUF4597 PF15366.6 RKP04136.1 - 0.2 11.4 1.4 9.4 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Ank_4 PF13637.6 RKP04137.1 - 1.9e-17 63.3 2.0 1.3e-07 32.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RKP04137.1 - 1.4e-15 57.2 5.5 9.7e-12 44.9 0.5 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKP04137.1 - 5.5e-14 52.5 1.8 7.5e-10 39.3 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKP04137.1 - 2.3e-12 45.9 1.7 0.002 18.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 RKP04137.1 - 6.9e-11 42.1 5.1 0.00045 20.5 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 RKP04138.1 - 1.6e-15 55.6 0.2 0.0011 19.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 RKP04138.1 - 9.4e-15 55.0 0.2 4.7e-14 52.7 0.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RKP04138.1 - 1.8e-13 50.3 1.2 0.00043 20.6 0.2 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 RKP04138.1 - 1.7e-11 44.1 1.5 1.3e-06 28.5 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 RKP04138.1 - 2.4e-11 43.9 1.1 7.9e-08 32.7 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NUDIX PF00293.28 RKP04139.1 - 1.4e-08 34.9 0.3 2e-08 34.4 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain CAP PF00188.26 RKP04140.1 - 4.1e-15 56.7 0.1 5.3e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Abhydrolase_1 PF00561.20 RKP04141.1 - 5.1e-12 46.0 0.3 1e-11 45.0 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKP04141.1 - 5.1e-05 22.7 0.4 0.00072 18.9 0.4 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1713 PF08213.11 RKP04142.1 - 3.2e-08 33.3 16.5 5.9e-08 32.5 16.5 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) UPF0193 PF05250.11 RKP04143.1 - 1.2e-17 64.4 0.4 1.6e-17 64.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Ribosomal_60s PF00428.19 RKP04143.1 - 1.3 9.7 7.3 13 6.5 1.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.32 RKP04144.1 - 0.025 15.4 5.1 43 5.2 0.0 5.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Chorion_S16 PF05836.12 RKP04144.1 - 0.21 11.8 4.5 0.29 11.4 3.3 1.9 1 1 0 1 1 1 0 Chorion protein S16 Abhydrolase_1 PF00561.20 RKP04145.1 - 4.3e-26 92.1 0.0 3.4e-25 89.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKP04145.1 - 1.3e-19 70.4 0.0 1.2e-16 60.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 RKP04145.1 - 1e-17 65.5 10.0 1.2e-17 65.2 10.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RKP04145.1 - 0.00027 20.9 0.0 0.0024 17.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 RKP04145.1 - 0.00046 19.9 0.1 0.001 18.8 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Ser_hydrolase PF06821.13 RKP04145.1 - 0.00084 19.2 0.0 0.0035 17.2 0.0 2.0 3 0 0 3 3 3 1 Serine hydrolase Abhydrolase_8 PF06259.12 RKP04145.1 - 0.0023 17.6 0.1 0.025 14.2 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase Peptidase_S9 PF00326.21 RKP04145.1 - 0.004 16.6 0.1 1.2 8.6 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 RKP04145.1 - 0.0064 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Ndr family LIDHydrolase PF10230.9 RKP04145.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 RKP04145.1 - 0.03 14.4 0.4 0.18 11.9 0.4 2.1 1 1 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 RKP04145.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 RKP04145.1 - 0.047 13.6 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 RKP04145.1 - 0.098 12.4 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 RKP04145.1 - 0.15 11.8 0.0 0.67 9.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.11 RKP04145.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Rpn3_C PF08375.11 RKP04146.1 - 1.1e-24 86.7 0.5 2.6e-24 85.4 0.5 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 RKP04146.1 - 8e-21 74.5 0.0 3.1e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain WH2 PF02205.20 RKP04146.1 - 0.0038 17.0 0.1 0.62 10.0 0.0 2.5 2 0 0 2 2 2 2 WH2 motif Ribosomal_L18 PF17135.4 RKP04147.1 - 2.9e-84 281.1 3.4 3.2e-84 281.0 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 RKP04147.1 - 0.068 13.8 0.0 0.099 13.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF2415 PF10313.9 RKP04148.1 - 5e-11 42.3 0.1 5.3e-10 39.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 RKP04148.1 - 3.8e-05 23.9 0.0 0.4 11.0 0.0 3.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKP04148.1 - 6.4e-05 23.6 8.0 0.87 10.6 0.2 4.5 4 1 1 5 5 5 2 WD domain, G-beta repeat Lgl_C PF08596.10 RKP04148.1 - 0.016 14.0 0.0 0.073 11.8 0.0 1.8 1 1 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal PD40 PF07676.12 RKP04148.1 - 0.022 14.7 0.0 3.8 7.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 RKP04148.1 - 0.029 14.4 0.0 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region W2 PF02020.18 RKP04149.1 - 1.2e-15 57.3 0.1 3e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 RKP04149.1 - 4.1e-12 45.3 8.2 1.8e-06 27.4 3.2 3.2 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 RKP04149.1 - 1.6e-06 27.9 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKP04149.1 - 2.2e-05 24.9 0.6 0.0015 18.9 0.0 2.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 RKP04149.1 - 0.0059 16.3 2.7 0.057 13.2 1.3 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Peptidase_S9_N PF02897.15 RKP04150.1 - 2e-92 310.2 0.1 2.7e-92 309.7 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 RKP04150.1 - 6.2e-58 195.8 0.3 1.3e-57 194.7 0.3 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM65_1 PF18259.1 RKP04150.1 - 0.026 14.7 0.1 0.078 13.1 0.1 1.9 1 0 0 1 1 1 0 Carbohydrate binding module 65 domain 1 Esterase PF00756.20 RKP04150.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Pyr_redox_2 PF07992.14 RKP04151.1 - 5.9e-50 170.2 0.0 7.5e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 RKP04151.1 - 5e-31 107.2 0.1 9.1e-31 106.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 RKP04151.1 - 1.7e-18 66.9 0.1 1.2e-15 57.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKP04151.1 - 1.2e-14 54.3 0.6 3e-14 53.0 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RKP04151.1 - 1.2e-06 28.2 0.6 2.2e-06 27.3 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RKP04151.1 - 5.1e-05 22.5 1.9 0.0013 17.9 1.9 2.3 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RKP04151.1 - 0.00033 19.9 0.9 0.0086 15.2 0.4 3.0 4 0 0 4 4 4 1 FAD binding domain HI0933_like PF03486.14 RKP04151.1 - 0.0015 17.4 0.0 0.013 14.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 RKP04151.1 - 0.012 15.8 0.6 0.03 14.5 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 RKP04151.1 - 0.013 15.3 1.0 2.1 8.2 0.0 3.3 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 RKP04151.1 - 0.026 14.1 0.4 0.098 12.2 0.4 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 RKP04151.1 - 0.074 12.3 0.1 0.65 9.3 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pex24p PF06398.11 RKP04152.1 - 0.00062 18.9 6.9 0.0011 18.1 6.9 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Peptidase_M76 PF09768.9 RKP04153.1 - 2e-62 209.9 1.0 2.4e-62 209.7 1.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 RKP04153.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 0 SprT-like family Tox-MPTase2 PF15638.6 RKP04153.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 GRAM PF02893.20 RKP04154.1 - 9.1e-15 54.5 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 GRAM domain DUF3496 PF12001.8 RKP04155.1 - 0.091 13.1 0.2 5.6 7.4 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3496) DUF842 PF05811.13 RKP04155.1 - 0.13 11.9 0.0 2.1 8.1 0.0 2.9 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF842) DUF16 PF01519.16 RKP04155.1 - 0.14 12.7 2.5 27 5.3 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 RKP04155.1 - 0.71 10.5 5.2 2.2 8.9 0.1 3.7 5 0 0 5 5 5 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 RKP04155.1 - 1.2 9.4 6.0 88 3.3 0.0 4.8 6 0 0 6 6 6 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 RKP04155.1 - 2.2 7.8 14.9 2.3 7.8 0.1 5.2 6 0 0 6 6 6 0 fzo-like conserved region Allexi_40kDa PF05549.11 RKP04155.1 - 2.7 7.4 8.3 36 3.7 0.0 4.2 5 0 0 5 5 5 0 Allexivirus 40kDa protein COG2 PF06148.11 RKP04155.1 - 8.2 6.5 10.1 20 5.2 0.0 4.5 4 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Glyco_hydro_16 PF00722.21 RKP04156.1 - 1.2e-30 106.3 0.2 1.8e-30 105.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PQ-loop PF04193.14 RKP04158.1 - 1e-17 63.6 8.1 1.1e-08 34.7 0.2 3.3 2 1 1 3 3 3 3 PQ loop repeat Flavodoxin_1 PF00258.25 RKP04159.1 - 5.7e-31 107.7 0.0 9.8e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 RKP04159.1 - 1.5e-23 83.5 0.0 1.2e-22 80.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 RKP04159.1 - 1.1e-09 38.9 0.0 3e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CAP_N PF01213.19 RKP04159.1 - 1.1 8.6 7.9 2.7 7.4 7.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CYYR1 PF10873.8 RKP04159.1 - 3.4 8.1 5.8 7.4 7.0 5.8 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Peptidase_M50 PF02163.22 RKP04160.1 - 5.8e-13 48.7 4.1 1e-11 44.6 4.1 2.3 1 1 0 1 1 1 1 Peptidase family M50 DUF2721 PF11026.8 RKP04160.1 - 8.8 6.2 10.0 0.19 11.6 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PTH2 PF01981.16 RKP04161.1 - 1.5e-38 131.7 0.0 2.4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ABC_membrane PF00664.23 RKP04162.1 - 1.1e-99 333.5 35.4 6e-52 177.0 14.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKP04162.1 - 1.9e-69 232.5 0.0 4.7e-34 117.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKP04162.1 - 2.2e-11 43.6 0.4 0.009 15.5 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RKP04162.1 - 8.8e-08 32.3 0.0 0.0019 18.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKP04162.1 - 6.8e-07 28.9 0.4 0.034 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RKP04162.1 - 1.2e-06 29.0 4.8 0.016 15.6 0.0 3.7 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 RKP04162.1 - 1.9e-06 28.2 0.2 0.46 10.8 0.0 4.0 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 RKP04162.1 - 4.8e-06 26.6 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 RKP04162.1 - 8.4e-06 24.8 0.2 0.00043 19.2 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF87 PF01935.17 RKP04162.1 - 0.00014 22.0 0.2 0.041 14.0 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 RKP04162.1 - 0.00018 21.3 0.1 0.33 10.7 0.1 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RKP04162.1 - 0.0004 19.7 0.0 0.72 9.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 RKP04162.1 - 0.00064 19.5 0.0 0.44 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 RKP04162.1 - 0.00076 19.3 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 RKP04162.1 - 0.0025 17.3 0.0 0.67 9.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 RKP04162.1 - 0.0032 17.5 0.0 0.66 10.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 RKP04162.1 - 0.0043 17.0 0.0 5.9 6.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 RKP04162.1 - 0.0048 16.8 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 RKP04162.1 - 0.0049 17.4 0.0 4.8 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 RKP04162.1 - 0.011 15.9 0.1 3.4 7.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 RKP04162.1 - 0.011 15.3 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 RKP04162.1 - 0.013 16.1 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 RKP04162.1 - 0.013 15.7 5.2 7.4 6.9 0.2 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 RKP04162.1 - 0.028 14.4 2.0 5.3 6.9 0.3 3.2 3 1 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 RKP04162.1 - 0.065 13.7 0.2 1.2e+02 3.1 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 RKP04162.1 - 0.07 12.3 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 RKP04162.1 - 0.088 12.0 0.0 8.3 5.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) PRK PF00485.18 RKP04162.1 - 0.099 12.4 0.1 5 6.8 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family VHS PF00790.19 RKP04163.1 - 2.4e-28 98.8 0.1 3.6e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 RKP04163.1 - 2.1e-06 27.2 0.0 4.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP04163.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 RKP04163.1 - 0.025 14.5 3.9 0.025 14.5 3.9 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif Mito_fiss_reg PF05308.11 RKP04163.1 - 4 7.5 7.4 0.54 10.3 3.4 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator ADIP PF11559.8 RKP04164.1 - 8e-13 48.7 9.0 8e-13 48.7 9.0 2.6 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding ERM PF00769.19 RKP04164.1 - 0.0021 17.9 3.0 0.0021 17.9 3.0 3.1 5 0 0 5 5 5 2 Ezrin/radixin/moesin family LPP PF04728.13 RKP04164.1 - 0.34 11.3 3.5 1.5 9.2 3.5 2.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Fez1 PF06818.15 RKP04164.1 - 1.2 9.6 14.6 1 9.8 7.9 2.4 2 0 0 2 2 2 0 Fez1 Spc7 PF08317.11 RKP04164.1 - 1.8 7.3 16.3 0.21 10.5 7.1 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2379 PF09543.10 RKP04164.1 - 9.5 6.4 15.8 20 5.4 7.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) Exonuc_VII_L PF02601.15 RKP04164.1 - 9.8 5.6 19.2 6 6.3 9.3 2.4 2 1 0 2 2 2 0 Exonuclease VII, large subunit PHD PF00628.29 RKP04165.1 - 6.5e-10 38.8 6.9 1e-09 38.1 6.9 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 RKP04165.1 - 0.00016 21.5 2.8 0.00016 21.5 2.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 RKP04165.1 - 0.00052 19.5 2.7 0.00052 19.5 2.7 1.6 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 RKP04165.1 - 0.0021 17.9 2.0 0.0021 17.9 2.0 1.6 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 RKP04165.1 - 0.055 13.1 0.4 0.055 13.1 0.4 1.4 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_9 PF13901.6 RKP04165.1 - 0.34 10.8 4.2 0.44 10.5 4.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon JmjC PF02373.22 RKP04166.1 - 1.5e-41 141.4 0.8 2.4e-41 140.7 0.8 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 RKP04166.1 - 3e-13 49.4 6.9 6.4e-13 48.4 6.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKP04166.1 - 0.11 12.0 0.9 0.32 10.6 0.9 1.9 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 RKP04166.1 - 0.26 11.7 8.1 0.75 10.2 7.7 2.1 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 RKP04166.1 - 0.47 10.4 3.9 0.33 10.9 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 RKP04166.1 - 0.68 10.1 5.3 0.63 10.2 3.9 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 RKP04166.1 - 3.7 7.8 6.8 4.7 7.5 5.3 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain CAF1A PF12253.8 RKP04167.1 - 1.8e-18 66.5 1.3 1.8e-18 66.5 1.3 1.9 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Exo_endo_phos PF03372.23 RKP04169.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Scs3p PF10261.9 RKP04170.1 - 6.2e-40 137.3 5.7 9e-39 133.4 5.7 2.0 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 RKP04170.1 - 0.067 12.9 0.3 0.067 12.9 0.3 2.2 3 0 0 3 3 3 0 PAP2 superfamily Aldo_ket_red PF00248.21 RKP04171.1 - 4.2e-50 170.6 0.0 7e-50 169.9 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 RKP04172.1 - 1.8e-38 132.4 29.6 2.2e-38 132.1 29.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RKP04172.1 - 1.4e-14 53.8 9.1 1.4e-14 53.8 9.1 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 RKP04172.1 - 0.001 18.0 17.9 0.008 15.1 2.5 3.0 1 1 2 3 3 3 2 MFS_1 like family MFS_4 PF06779.14 RKP04172.1 - 0.0014 18.0 18.6 0.0021 17.4 1.0 2.6 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 RKP04172.1 - 0.011 14.2 1.4 0.02 13.3 1.4 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector DivIVA PF05103.13 RKP04173.1 - 0.0073 16.4 2.1 0.0073 16.4 2.1 2.0 2 0 0 2 2 2 1 DivIVA protein RXT2_N PF08595.11 RKP04173.1 - 0.01 15.9 0.2 0.044 13.8 0.2 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal CortBP2 PF09727.9 RKP04173.1 - 0.95 9.3 5.6 0.18 11.7 1.2 1.8 2 0 0 2 2 2 0 Cortactin-binding protein-2 Spc7 PF08317.11 RKP04173.1 - 2.1 7.1 5.7 2.6 6.8 1.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein NOA36 PF06524.12 RKP04173.1 - 2.3 7.4 12.6 5.5 6.2 12.6 1.5 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_21 PF13506.6 RKP04174.1 - 3.3e-36 124.3 0.0 5.6e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 RKP04174.1 - 2.9e-15 56.8 0.0 4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RKP04174.1 - 5.6e-09 36.2 9.2 1.5e-08 34.8 9.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 RKP04174.1 - 7e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 CTP_transf_1 PF01148.20 RKP04175.1 - 2.7e-69 233.9 15.0 3.5e-69 233.5 15.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SH3_9 PF14604.6 RKP04176.1 - 1.7e-44 149.5 2.7 1.4e-12 47.2 0.0 4.9 5 0 0 5 5 5 4 Variant SH3 domain SH3_1 PF00018.28 RKP04176.1 - 3.5e-43 145.0 0.0 1.1e-13 50.5 0.0 4.7 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 RKP04176.1 - 1.3e-25 88.9 0.0 2.5e-08 33.5 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain FCH PF00611.23 RKP04176.1 - 8.5e-09 35.6 1.3 1.8e-08 34.5 0.5 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4570 PF15134.6 RKP04176.1 - 0.012 15.6 6.8 0.044 13.8 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4570) DUF5599 PF18141.1 RKP04176.1 - 0.051 13.8 0.0 3 8.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5599) SH3_16 PF18348.1 RKP04176.1 - 0.11 12.3 0.9 4.1 7.3 0.0 3.5 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain Lipase_GDSL_2 PF13472.6 RKP04177.1 - 1.2e-11 45.4 0.9 1.9e-11 44.7 0.9 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF5063 PF16702.5 RKP04178.1 - 0.05 14.0 0.1 2.5 8.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) zinc_ribbon_10 PF10058.9 RKP04179.1 - 8.2e-14 51.1 0.0 1.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Serglycin PF04360.12 RKP04180.1 - 0.0044 17.0 0.3 0.0072 16.3 0.3 1.3 1 0 0 1 1 1 1 Serglycin TLD PF07534.16 RKP04181.1 - 2.3e-32 112.1 0.0 2.6e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 TLD LSM PF01423.22 RKP04182.1 - 3.4e-12 45.9 0.1 4.6e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain NTP_transferase PF00483.23 RKP04183.1 - 3.6e-31 108.6 0.0 4.9e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKP04183.1 - 5.6e-07 30.0 0.0 8.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 RKP04183.1 - 5.8e-06 25.8 5.6 1.6e-05 24.4 0.2 3.5 3 1 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RKP04183.1 - 0.0024 17.6 0.5 0.035 13.9 0.1 2.6 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase LRR_8 PF13855.6 RKP04184.1 - 7.4e-10 38.5 0.0 0.00038 20.2 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 RKP04184.1 - 5.3e-08 33.0 0.0 0.027 14.9 0.0 4.0 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKP04184.1 - 0.0081 16.6 0.0 19 6.3 0.0 4.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 RKP04184.1 - 0.07 13.2 1.2 1.1e+02 3.3 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Exo_endo_phos PF03372.23 RKP04185.1 - 7.2e-16 58.4 1.6 1e-14 54.6 1.6 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 RKP04187.1 - 8.3e-41 140.1 43.9 1.4e-40 139.3 43.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RKP04187.1 - 2.3e-14 53.2 9.5 2.3e-14 53.2 9.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 RKP04187.1 - 0.00071 18.5 2.7 0.024 13.5 2.2 2.2 1 1 1 2 2 2 2 MFS_1 like family Trehalase PF01204.18 RKP04189.1 - 7.9e-127 424.2 0.0 1.4e-126 423.3 0.0 1.4 1 1 0 1 1 1 1 Trehalase Glyco_hydro_92 PF07971.12 RKP04189.1 - 0.017 14.1 0.4 0.028 13.4 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 92 DUF4777 PF16007.5 RKP04189.1 - 0.15 12.3 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Pkinase PF00069.25 RKP04190.1 - 9.7e-33 113.6 0.0 1e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP04190.1 - 1.6e-15 57.1 0.0 1.7e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKP04190.1 - 0.00033 20.1 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKP04190.1 - 0.00058 19.3 0.0 0.0008 18.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKP04190.1 - 0.016 15.1 0.1 0.021 14.7 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 RKP04190.1 - 0.12 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RKP04190.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 RKP04190.1 - 0.16 10.9 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Mpv17_PMP22 PF04117.12 RKP04191.1 - 1.2e-16 60.7 0.4 1.2e-16 60.7 0.4 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Robl_LC7 PF03259.17 RKP04193.1 - 1e-26 92.5 0.0 1.1e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 RKP04193.1 - 0.00014 21.7 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 NTP_transferase PF00483.23 RKP04194.1 - 3.7e-51 174.1 0.0 4.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKP04194.1 - 2.2e-09 37.9 0.0 3e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 RKP04194.1 - 1.2e-08 34.3 0.8 4.9e-05 22.9 0.1 3.4 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RKP04194.1 - 0.069 12.9 0.4 1.7 8.4 0.2 2.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase EAF PF09816.9 RKP04195.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NOA36 PF06524.12 RKP04195.1 - 0.72 9.1 4.5 1.2 8.4 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein MSP1_C PF07462.11 RKP04195.1 - 2.3 6.8 20.6 0.053 12.2 2.8 2.3 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus AAA PF00004.29 RKP04196.1 - 1.1e-35 122.9 0.0 1.9e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKP04196.1 - 3.8e-13 49.0 0.0 8.2e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKP04196.1 - 2.1e-06 27.8 0.0 7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKP04196.1 - 2.3e-06 28.1 2.1 0.00016 22.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RKP04196.1 - 6.2e-06 26.5 0.8 0.0074 16.6 0.0 3.1 1 1 2 3 3 3 1 AAA domain RuvB_N PF05496.12 RKP04196.1 - 8.1e-06 25.7 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 RKP04196.1 - 2.4e-05 24.4 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKP04196.1 - 5e-05 23.9 0.0 0.00021 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 RKP04196.1 - 6.3e-05 23.3 0.0 0.0015 18.9 0.0 2.4 1 1 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 RKP04196.1 - 0.00011 22.3 0.1 0.00034 20.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 RKP04196.1 - 0.00032 20.3 0.4 0.028 14.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RKP04196.1 - 0.00079 18.9 0.2 0.0021 17.5 0.1 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RKP04196.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 RKP04196.1 - 0.002 18.1 0.1 0.013 15.4 0.0 2.1 1 1 0 2 2 2 1 NACHT domain Rad17 PF03215.15 RKP04196.1 - 0.0024 17.8 0.0 0.0064 16.4 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 RKP04196.1 - 0.0029 17.9 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 RKP04196.1 - 0.0032 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.6 RKP04196.1 - 0.0036 17.4 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain TniB PF05621.11 RKP04196.1 - 0.004 16.6 0.0 1.8 7.9 0.0 2.3 1 1 0 2 2 2 1 Bacterial TniB protein AAA_2 PF07724.14 RKP04196.1 - 0.0065 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 RKP04196.1 - 0.0073 15.8 0.0 0.025 14.1 0.0 1.9 1 1 1 2 2 2 1 P-loop containing dynein motor region CPT PF07931.12 RKP04196.1 - 0.0077 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 RKP04196.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 RKP04196.1 - 0.011 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 RKP04196.1 - 0.015 15.1 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RKP04196.1 - 0.024 15.1 0.0 0.053 14.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 RKP04196.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RKP04196.1 - 0.026 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.6 RKP04196.1 - 0.027 14.3 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 RKP04196.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 RKP04196.1 - 0.045 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 RKP04196.1 - 0.049 13.3 0.0 0.9 9.2 0.0 2.6 1 1 1 3 3 3 0 Guanylate kinase AAA_17 PF13207.6 RKP04196.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKP04196.1 - 0.058 12.5 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 RKP04196.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 RKP04196.1 - 0.12 11.7 0.1 1.1 8.5 0.0 2.1 1 1 1 2 2 2 0 KaiC tRNA_lig_kinase PF08303.11 RKP04196.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain Hydin_ADK PF17213.3 RKP04196.1 - 0.21 11.9 0.0 2.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Viral_helicase1 PF01443.18 RKP04196.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zf-ANAPC11 PF12861.7 RKP04197.1 - 1.5e-36 124.3 9.5 1.6e-36 124.2 9.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 RKP04197.1 - 7e-22 77.5 12.1 9.1e-22 77.1 12.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 RKP04197.1 - 2.2e-05 24.7 14.1 0.00044 20.5 14.3 2.2 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 RKP04197.1 - 0.0032 17.4 8.7 0.007 16.4 8.7 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RKP04197.1 - 0.013 15.4 11.9 0.048 13.5 11.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKP04197.1 - 0.013 15.3 6.2 0.013 15.3 6.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 RKP04197.1 - 0.071 12.7 18.1 0.21 11.2 14.9 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 RKP04197.1 - 0.073 13.0 10.7 0.65 10.0 11.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 RKP04197.1 - 0.22 11.4 7.9 0.43 10.4 3.6 2.3 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 RKP04197.1 - 0.97 9.8 11.1 3.5 8.0 11.1 2.0 1 1 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 RKP04197.1 - 1.2 9.0 15.1 17 5.3 15.1 2.3 1 1 0 1 1 1 0 RING-like zinc finger RINGv PF12906.7 RKP04197.1 - 6.2 7.0 13.8 44 4.3 11.6 2.4 1 1 1 2 2 2 0 RING-variant domain Sacchrp_dh_C PF16653.5 RKP04198.1 - 7.5e-84 281.9 0.0 1e-83 281.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 RKP04198.1 - 9.8e-22 77.6 0.7 1.7e-21 76.9 0.7 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 RKP04198.1 - 0.00012 22.2 0.1 0.00026 21.1 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 RKP04198.1 - 0.00019 21.4 0.7 0.00037 20.4 0.7 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 RKP04198.1 - 0.023 15.1 0.1 0.038 14.4 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 RKP04198.1 - 0.12 12.8 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NMD3 PF04981.13 RKP04199.1 - 9.3e-79 264.3 2.1 1.4e-78 263.8 2.1 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 RKP04199.1 - 0.035 14.1 6.7 1.1 9.3 0.4 2.9 2 1 0 2 2 2 0 Double zinc ribbon DUF1289 PF06945.13 RKP04199.1 - 0.069 13.0 0.3 16 5.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF35_N PF12172.8 RKP04199.1 - 7.4 6.6 8.9 41 4.2 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Guanylate_cyc PF00211.20 RKP04200.1 - 1.6e-39 135.5 0.0 2.7e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF_3 PF13492.6 RKP04200.1 - 2.2e-12 47.5 0.0 6.8e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 RKP04200.1 - 3.7e-12 46.7 0.0 1.5e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 RKP04200.1 - 1.4e-10 41.9 0.0 3.8e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 GAF domain FHA PF00498.26 RKP04200.1 - 6.4e-06 26.4 0.1 2e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 RKP04200.1 - 0.0079 16.5 0.0 0.056 13.8 0.0 2.2 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Glyco_trans_2_3 PF13632.6 RKP04202.1 - 1.5e-18 67.4 0.6 1.5e-18 67.4 0.6 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 RKP04202.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ribonuclease_3 PF00636.26 RKP04203.1 - 2.6e-20 73.0 0.0 2.3e-18 66.7 0.0 3.1 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 RKP04203.1 - 1e-14 54.8 0.2 1.6e-11 44.5 0.1 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 RKP04203.1 - 0.00053 20.6 0.0 0.0016 19.1 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif SR-25 PF10500.9 RKP04203.1 - 0.0022 17.7 10.3 0.0022 17.7 10.3 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SBE2 PF17076.5 RKP04203.1 - 3.3 5.8 5.2 4.6 5.4 5.2 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Ribonuclease_3 PF00636.26 RKP04204.1 - 1.9e-42 144.2 0.0 4.4e-21 75.5 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 RKP04204.1 - 3.7e-27 95.0 0.0 8.2e-11 42.2 0.0 4.0 4 0 0 4 4 4 3 Ribonuclease-III-like DEAD PF00270.29 RKP04204.1 - 5.3e-15 55.6 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RKP04204.1 - 6.4e-13 49.1 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKP04204.1 - 7.4e-12 45.6 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 RKP04204.1 - 0.00041 21.0 0.0 0.00093 19.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif SPA PF08616.10 RKP04206.1 - 1.5e-22 79.7 0.0 2.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 RKP04206.1 - 1.1e-11 45.3 3.0 2.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 RKP04206.1 - 2.2e-05 24.2 0.0 0.00014 21.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 RKP04206.1 - 0.00011 21.1 0.0 0.028 13.1 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 BUD22 PF09073.10 RKP04206.1 - 1.7 7.9 5.3 0.71 9.2 2.2 1.9 2 0 0 2 2 2 0 BUD22 ArsA_ATPase PF02374.15 RKP04207.1 - 3.5e-111 371.2 0.1 4.2e-111 371.0 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 RKP04207.1 - 1.6e-12 47.7 0.1 7.3e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 RKP04207.1 - 2.4e-10 40.5 0.0 5.6e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 RKP04207.1 - 4.5e-05 23.0 0.5 0.00067 19.2 0.0 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 RKP04207.1 - 5.9e-05 22.7 0.0 0.00017 21.2 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 RKP04207.1 - 0.0001 21.9 0.0 0.00027 20.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 RKP04207.1 - 0.0012 18.5 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 RKP04207.1 - 0.033 13.4 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 RKP04207.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 RKP04207.1 - 0.16 11.5 0.6 0.93 9.0 0.6 2.1 1 1 0 1 1 1 0 AAA domain Nkap_C PF06047.11 RKP04208.1 - 2.4e-45 152.8 3.3 5.9e-45 151.6 3.3 1.7 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Nop14 PF04147.12 RKP04209.1 - 1.6e-160 536.2 36.9 1.4e-157 526.5 36.9 3.0 1 1 0 1 1 1 1 Nop14-like family BSP_II PF05432.11 RKP04209.1 - 0.0011 18.8 11.0 0.0011 18.8 11.0 1.9 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 RKP04209.1 - 2.2 6.3 32.8 4.5 5.3 32.8 1.4 1 0 0 1 1 1 0 DNA polymerase phi Prefoldin PF02996.17 RKP04210.1 - 1.7e-12 47.3 0.1 2.8e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit DUF3138 PF11336.8 RKP04210.1 - 0.016 13.8 10.3 0.011 14.4 8.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) T3SSipB PF16535.5 RKP04210.1 - 1.9 9.0 10.0 0.29 11.6 6.0 1.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB TIP49 PF06068.13 RKP04211.1 - 7e-170 564.9 1.0 9.7e-170 564.4 1.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 RKP04211.1 - 9.4e-23 80.1 0.1 2.7e-22 78.6 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 RKP04211.1 - 2.6e-10 40.3 0.3 4.3e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 RKP04211.1 - 5.3e-10 39.8 0.1 2.8e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKP04211.1 - 7.6e-06 26.2 0.2 0.075 13.3 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RKP04211.1 - 7.9e-05 23.1 0.0 0.00073 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 RKP04211.1 - 9.7e-05 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKP04211.1 - 0.00011 22.5 0.1 0.00026 21.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RKP04211.1 - 0.0002 21.4 0.1 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 RKP04211.1 - 0.00046 20.7 0.0 0.0017 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 RKP04211.1 - 0.00099 18.9 0.1 0.65 9.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 RKP04211.1 - 0.0012 19.1 2.0 1 9.7 0.1 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 RKP04211.1 - 0.0033 16.8 0.2 0.015 14.6 0.1 2.0 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 RKP04211.1 - 0.0044 16.4 0.2 0.18 11.2 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKP04211.1 - 0.0074 16.5 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RKP04211.1 - 0.013 15.5 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 RKP04211.1 - 0.015 14.7 0.0 0.042 13.2 0.0 1.6 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 RKP04211.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 RKP04211.1 - 0.028 13.8 0.2 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 RKP04211.1 - 0.055 13.2 0.3 3.1 7.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKP04211.1 - 0.056 13.0 0.2 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region PIF1 PF05970.14 RKP04211.1 - 0.057 12.6 0.4 3.1 6.9 0.0 2.6 3 0 0 3 3 3 0 PIF1-like helicase NACHT PF05729.12 RKP04211.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 RKP04211.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) S-AdoMet_synt_C PF02773.16 RKP04211.1 - 0.087 12.8 0.1 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain TsaE PF02367.17 RKP04211.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zn_clus PF00172.18 RKP04212.1 - 1.6 8.9 17.2 0.056 13.6 10.9 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC158 PF15921.5 RKP04212.1 - 9.2 3.9 5.5 13 3.5 5.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 DNA_pol_A_exo1 PF01612.20 RKP04213.1 - 8.4e-48 162.4 4.2 1.2e-47 161.9 4.2 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 RKP04213.1 - 3.3e-12 46.2 0.0 6.4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 RKP04213.1 - 0.066 13.9 0.4 0.15 12.8 0.4 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain CLASP_N PF12348.8 RKP04214.1 - 3.9e-08 33.1 0.0 0.00051 19.7 0.0 2.6 2 1 0 3 3 3 2 CLASP N terminal NUC173 PF08161.12 RKP04214.1 - 0.00078 19.1 0.6 0.29 10.7 0.0 2.3 2 0 0 2 2 2 2 NUC173 domain DUF3446 PF11928.8 RKP04214.1 - 0.017 15.4 3.2 0.017 15.4 3.2 6.1 4 2 2 6 6 6 0 Early growth response N-terminal domain MoaC PF01967.21 RKP04214.1 - 0.15 12.1 1.0 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 MoaC family Steroid_dh PF02544.16 RKP04216.1 - 8.2e-33 113.5 0.4 1.3e-32 112.8 0.4 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 RKP04216.1 - 0.01 15.4 1.3 0.014 14.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PEMT PF04191.13 RKP04216.1 - 0.022 15.1 1.0 0.057 13.8 0.6 1.8 1 1 0 1 1 1 0 Phospholipid methyltransferase Suppressor_APC PF11414.8 RKP04217.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DEAD PF00270.29 RKP04218.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3235 PF11574.8 RKP04218.1 - 0.039 14.8 1.5 0.039 14.8 1.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3235) Sec7 PF01369.20 RKP04219.1 - 3.4e-62 209.4 0.3 5.5e-62 208.7 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain Homeodomain PF00046.29 RKP04219.1 - 9.9e-09 34.9 0.4 5.4e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Homeodomain Sec7_N PF12783.7 RKP04219.1 - 0.00018 21.4 0.7 0.0075 16.2 0.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal UPRTase PF14681.6 RKP04220.1 - 5.3e-78 261.2 0.0 6.3e-78 261.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 RKP04220.1 - 0.0026 17.3 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Lactamase_B_6 PF16661.5 RKP04221.1 - 2.2e-23 82.7 0.0 4.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 RKP04221.1 - 1.4e-22 80.1 0.0 2.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 RKP04221.1 - 4.4e-18 65.0 0.0 7.9e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 RKP04221.1 - 5.1e-13 49.5 0.5 1.7e-12 47.8 0.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 RKP04221.1 - 2.9e-08 33.5 2.1 8.3e-08 32.0 0.4 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 RKP04221.1 - 4.6e-05 23.4 0.0 0.00054 19.9 0.0 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Acetyltransf_1 PF00583.25 RKP04222.1 - 1.8e-06 28.2 0.0 3.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AF-4 PF05110.13 RKP04222.1 - 0.00018 19.8 5.8 0.00025 19.3 5.8 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Acetyltransf_7 PF13508.7 RKP04222.1 - 0.0009 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain XRN_N PF03159.18 RKP04222.1 - 0.0026 17.2 0.4 0.0039 16.7 0.4 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Acetyltransf_10 PF13673.7 RKP04222.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Totivirus_coat PF05518.11 RKP04222.1 - 0.036 12.1 3.9 0.057 11.5 3.9 1.3 1 0 0 1 1 1 0 Totivirus coat protein FR47 PF08445.10 RKP04222.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Complex1_51K PF01512.17 RKP04223.1 - 2.1e-48 164.0 0.0 3.6e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 RKP04223.1 - 3.4e-28 97.5 0.2 6.7e-28 96.6 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 RKP04223.1 - 3e-09 36.6 0.0 5.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 RKP04223.1 - 0.11 12.5 1.3 0.24 11.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) MOZART1 PF12554.8 RKP04225.1 - 8.1e-18 63.9 0.5 9e-18 63.8 0.5 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Spt4 PF06093.13 RKP04226.1 - 5.6e-28 96.9 0.2 6.8e-28 96.6 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DTW PF03942.15 RKP04227.1 - 1.7e-20 73.6 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 DTW domain Proteasome PF00227.26 RKP04228.1 - 6.9e-46 156.1 0.1 8.5e-46 155.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKP04228.1 - 1e-11 44.2 0.1 2.3e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sel1 PF08238.12 RKP04229.1 - 1e-10 41.9 13.7 3.2e-05 24.5 1.0 5.2 4 0 0 4 4 4 3 Sel1 repeat TPR_14 PF13428.6 RKP04229.1 - 0.0023 18.6 3.2 0.0023 18.6 3.2 5.3 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKP04229.1 - 0.0064 16.6 0.2 0.096 13.0 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ELYS PF13934.6 RKP04229.1 - 0.021 14.8 0.2 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Nuclear pore complex assembly GSH-S_N PF02951.14 RKP04229.1 - 0.028 14.5 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain TPR_6 PF13174.6 RKP04229.1 - 0.037 14.7 7.7 0.52 11.1 0.8 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKP04229.1 - 0.05 13.9 8.1 0.14 12.5 5.3 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKP04229.1 - 0.051 13.7 1.8 0.051 13.7 1.8 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKP04229.1 - 0.072 13.1 2.8 0.32 11.1 1.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Raptor_N PF14538.6 RKP04230.1 - 2.9e-63 212.2 0.0 4.7e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 RKP04230.1 - 0.00019 21.4 2.4 0.047 14.0 0.1 4.3 4 0 0 4 4 4 1 HEAT repeat Atx10homo_assoc PF09759.9 RKP04230.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 RKP04230.1 - 0.012 15.7 0.0 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKP04230.1 - 0.015 15.6 2.6 1.8 9.0 2.0 3.0 2 0 0 2 2 2 0 HEAT repeats WD40 PF00400.32 RKP04230.1 - 0.02 15.7 3.8 3.3 8.7 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat Arm PF00514.23 RKP04230.1 - 0.071 13.2 0.3 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SIR2 PF02146.17 RKP04231.1 - 2.1e-36 125.5 0.0 3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family SAGA-Tad1 PF12767.7 RKP04233.1 - 2e-18 67.0 0.0 8.7e-18 64.9 0.0 1.8 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Phage_tail_APC PF16778.5 RKP04233.1 - 0.035 14.0 1.4 0.3 11.0 0.5 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein CSTF_C PF14304.6 RKP04233.1 - 0.042 13.4 0.3 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Pkinase PF00069.25 RKP04234.1 - 1.7e-63 214.4 0.0 2e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKP04234.1 - 5.1e-36 124.3 0.0 6.5e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKP04234.1 - 3e-06 27.3 0.0 0.00055 19.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 RKP04234.1 - 8.5e-06 25.3 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKP04234.1 - 0.00025 20.1 0.0 0.00038 19.5 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKP04234.1 - 0.00038 19.9 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RKP04234.1 - 0.031 13.9 0.1 7.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RKP04234.1 - 0.2 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PDT PF00800.18 RKP04235.1 - 1.1e-53 181.7 0.0 1.5e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 RKP04235.1 - 3.8e-08 33.0 0.0 7.5e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain CHCH PF06747.13 RKP04236.1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.4 1 1 0 1 1 1 0 CHCH domain zf-C2HC5 PF06221.13 RKP04237.1 - 5.8e-14 51.8 6.0 9.8e-14 51.1 6.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type BAR_2 PF10455.9 RKP04238.1 - 1.8e-41 142.2 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 RKP04238.1 - 8.2e-23 81.3 1.3 2.7e-22 79.6 1.3 1.7 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RKP04238.1 - 3.6e-06 26.9 0.0 7.9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 RKP04238.1 - 1.4e-05 24.8 1.6 0.0032 17.1 0.1 2.3 1 1 1 2 2 2 2 Arfaptin-like domain Ribosom_S30AE_C PF16321.5 RKP04238.1 - 0.046 13.4 0.3 0.087 12.5 0.3 1.4 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus ParD_antitoxin PF03693.14 RKP04238.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DivIC PF04977.15 RKP04238.1 - 0.14 11.9 1.0 0.69 9.7 0.0 2.4 3 0 0 3 3 3 0 Septum formation initiator Epiglycanin_TR PF05647.11 RKP04238.1 - 2.1 8.3 4.8 9.6 6.2 1.2 2.3 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Methyltransf_16 PF10294.9 RKP04239.1 - 3.6e-09 36.6 0.0 7.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase zf-C2H2 PF00096.26 RKP04240.1 - 4.9e-08 33.0 16.1 0.0009 19.6 6.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKP04240.1 - 9.3e-05 22.9 13.5 0.0037 18.0 4.6 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKP04240.1 - 0.0025 17.6 2.9 0.0025 17.6 2.9 1.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 RKP04240.1 - 0.01 16.2 6.7 0.01 16.2 6.7 3.1 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 RKP04240.1 - 0.014 15.4 7.3 0.022 14.7 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Fer4_6 PF12837.7 RKP04240.1 - 0.03 14.4 0.4 0.03 14.4 0.4 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain QueC PF06508.13 RKP04240.1 - 0.33 10.4 2.8 0.34 10.4 2.6 1.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Taq-exonuc PF09281.10 RKP04241.1 - 0.0078 16.2 0.2 0.023 14.7 0.2 1.8 1 0 0 1 1 1 1 Taq polymerase, exonuclease EPL1 PF10513.9 RKP04241.1 - 0.15 12.4 1.2 0.33 11.3 1.2 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like EIF4E-T PF10477.9 RKP04241.1 - 6.4 5.5 12.6 11 4.7 12.6 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E BAR PF03114.18 RKP04242.1 - 1.9e-26 93.2 0.0 2.5e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 RKP04242.1 - 1e-14 53.9 0.0 1.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKP04242.1 - 7.6e-12 44.9 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKP04242.1 - 1.2e-07 31.2 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.11 RKP04242.1 - 0.027 13.9 0.7 0.043 13.2 0.7 1.2 1 0 0 1 1 1 0 FAM92 protein Med2 PF11214.8 RKP04242.1 - 0.15 12.2 1.5 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 Mad3_BUB1_I PF08311.12 RKP04243.1 - 2e-31 108.5 0.7 3.2e-31 107.9 0.7 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 CAP_N PF01213.19 RKP04243.1 - 0.0012 18.4 7.1 0.0012 18.4 7.1 4.6 6 1 0 6 6 6 1 Adenylate cyclase associated (CAP) N terminal Mad3_BUB1_I_2 PF17014.5 RKP04243.1 - 0.0053 16.9 0.1 0.0095 16.1 0.1 1.3 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein DUF4404 PF14357.6 RKP04243.1 - 0.085 13.5 0.4 0.32 11.6 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Pkinase PF00069.25 RKP04243.1 - 0.18 11.1 0.1 0.58 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Na_Ca_ex PF01699.24 RKP04244.1 - 1.3e-10 41.4 42.3 1.2e-07 31.8 13.5 3.6 4 0 0 4 4 3 2 Sodium/calcium exchanger protein YccF PF03733.13 RKP04244.1 - 5.8e-09 36.5 15.5 5.8e-09 36.5 15.5 4.3 5 0 0 5 5 2 1 Inner membrane component domain Sigma70_ner PF04546.13 RKP04244.1 - 0.098 12.5 10.1 0.15 11.9 10.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 RKP04244.1 - 0.42 8.8 13.8 0.58 8.3 13.8 1.0 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 RKP04244.1 - 0.65 8.2 4.4 0.93 7.7 4.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mpp10 PF04006.12 RKP04244.1 - 1 7.8 10.1 1.4 7.3 10.1 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 RKP04244.1 - 1.1 8.6 13.9 1.6 8.1 13.9 1.1 1 0 0 1 1 1 0 SDA1 GCIP PF13324.6 RKP04244.1 - 1.1 8.8 6.1 2.4 7.7 6.1 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Utp14 PF04615.13 RKP04244.1 - 2.4 6.7 7.5 3.2 6.2 7.5 1.0 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 RKP04244.1 - 4.6 5.2 24.4 6.5 4.7 24.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 RKP04244.1 - 7.9 4.6 13.2 11 4.1 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1104 PF06518.11 RKP04245.1 - 0.15 12.5 1.2 0.51 10.7 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) IMD PF08397.11 RKP04245.1 - 0.22 10.9 2.0 0.35 10.2 2.0 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Syntaxin_2 PF14523.6 RKP04247.1 - 3.1e-16 59.6 0.3 5.7e-15 55.5 0.0 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 RKP04247.1 - 4.2e-08 33.1 9.8 5.8e-08 32.7 9.8 1.3 1 1 0 1 1 1 1 Syntaxin AAA_13 PF13166.6 RKP04247.1 - 0.00043 19.1 3.0 0.00051 18.8 3.0 1.0 1 0 0 1 1 1 1 AAA domain End3 PF12761.7 RKP04247.1 - 0.003 17.8 3.3 0.0041 17.3 3.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.19 RKP04247.1 - 0.016 13.2 5.7 0.021 12.7 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4715 PF15835.5 RKP04247.1 - 0.033 14.3 5.0 0.05 13.7 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) NAP PF00956.18 RKP04247.1 - 0.14 11.3 1.6 0.2 10.8 1.6 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) FAM76 PF16046.5 RKP04247.1 - 0.24 10.7 2.4 0.28 10.5 2.4 1.2 1 0 0 1 1 1 0 FAM76 protein WD40 PF00400.32 RKP04248.1 - 5.2e-07 30.3 0.1 0.15 13.0 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat HSF_DNA-bind PF00447.17 RKP04249.1 - 5.2e-16 59.0 0.1 5.5e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding SWIRM-assoc_2 PF16496.5 RKP04250.1 - 4.8e-25 88.3 6.4 2.4e-17 62.9 11.1 3.1 2 2 0 2 2 2 2 SWIRM-associated domain at the N-terminal SWIRM-assoc_1 PF16495.5 RKP04250.1 - 0.0049 16.8 1.0 0.013 15.4 1.0 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 RKP04250.1 - 0.047 14.0 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 SWIRM domain LIG3_BRCT PF16759.5 RKP04250.1 - 0.23 11.8 0.1 0.49 10.7 0.1 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Phosphoprotein PF00922.17 RKP04250.1 - 0.82 9.2 4.6 1.5 8.3 4.6 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein IQ PF00612.27 RKP04251.1 - 8.5e-12 43.8 39.0 0.0025 17.5 0.1 8.6 8 0 0 8 8 8 6 IQ calmodulin-binding motif DUF2433 PF10360.9 RKP04251.1 - 0.095 12.8 0.2 0.26 11.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Ribosomal_S17 PF00366.20 RKP04252.1 - 1e-19 70.4 0.3 1.2e-19 70.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 VOMI PF03762.17 RKP04252.1 - 0.065 13.4 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) Bap31 PF05529.12 RKP04253.1 - 3.5e-27 94.9 6.1 4.4e-27 94.6 6.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region YniB PF14002.6 RKP04253.1 - 0.059 13.1 2.3 0.57 9.9 0.6 2.1 2 0 0 2 2 2 0 YniB-like protein DivIC PF04977.15 RKP04253.1 - 0.98 9.2 7.3 2.7 7.8 0.1 2.9 2 1 0 2 2 2 0 Septum formation initiator Bap31_Bap29_C PF18035.1 RKP04253.1 - 4.3 7.4 6.5 7.6 6.6 6.5 1.5 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Birna_VP4 PF01768.16 RKP04254.1 - 4.8 6.9 5.5 21 4.8 0.8 2.5 2 0 0 2 2 2 0 Birnavirus VP4 protein GST_C_6 PF17171.4 RKP04255.1 - 8.3e-10 38.3 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dscam_C PF12355.8 RKP04255.1 - 0.036 15.0 0.2 0.058 14.4 0.2 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Glyco_transf_21 PF13506.6 RKP04255.1 - 0.076 12.5 0.3 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Rft-1 PF04506.13 RKP04256.1 - 6.5e-94 315.5 0.0 1.1e-93 314.7 0.0 1.3 1 1 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.6 RKP04256.1 - 0.00055 20.0 9.6 0.00055 20.0 9.6 2.8 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain TPR_1 PF00515.28 RKP04257.1 - 1.1e-43 145.3 48.6 0.00031 20.4 0.1 23.4 25 0 0 25 25 25 14 Tetratricopeptide repeat TPR_2 PF07719.17 RKP04257.1 - 4.2e-41 135.8 72.0 0.012 15.6 0.3 23.2 25 0 0 25 25 24 13 Tetratricopeptide repeat TPR_11 PF13414.6 RKP04257.1 - 1.7e-33 114.0 19.1 0.0017 18.0 0.2 17.2 14 4 5 19 19 19 6 TPR repeat TPR_19 PF14559.6 RKP04257.1 - 8e-26 90.3 46.1 1.3e-05 25.6 0.0 14.1 9 4 8 17 17 16 7 Tetratricopeptide repeat TPR_16 PF13432.6 RKP04257.1 - 6e-25 87.6 120.7 0.00016 22.3 0.7 19.1 14 5 6 21 21 18 13 Tetratricopeptide repeat TPR_9 PF13371.6 RKP04257.1 - 2.4e-23 82.1 83.4 2.9e-05 24.1 1.3 17.9 8 4 12 21 21 21 9 Tetratricopeptide repeat TPR_8 PF13181.6 RKP04257.1 - 3.7e-22 76.6 25.5 0.043 14.0 0.2 16.4 19 0 0 19 19 17 5 Tetratricopeptide repeat TPR_17 PF13431.6 RKP04257.1 - 3.5e-21 74.0 29.4 0.029 14.7 0.1 15.4 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_14 PF13428.6 RKP04257.1 - 4.9e-13 48.7 86.9 0.022 15.5 0.1 19.2 12 6 9 21 21 19 6 Tetratricopeptide repeat TPR_12 PF13424.6 RKP04257.1 - 8.2e-13 48.5 70.8 0.001 19.3 1.4 13.9 12 3 2 14 14 14 6 Tetratricopeptide repeat TPR_7 PF13176.6 RKP04257.1 - 1.3e-09 37.4 29.3 0.016 15.2 0.1 12.0 12 0 0 12 12 12 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKP04257.1 - 0.00063 19.8 0.0 0.033 14.2 0.1 3.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 RKP04257.1 - 0.0008 19.6 32.0 0.0013 18.9 0.9 7.2 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 RKP04257.1 - 0.004 17.5 19.9 2.8 8.3 0.0 8.6 7 2 2 9 9 9 1 Tetratricopeptide repeat NARP1 PF12569.8 RKP04257.1 - 0.015 14.2 5.0 5.5 5.8 0.2 4.3 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 RKP04257.1 - 0.044 14.4 43.9 2.5 8.9 0.3 14.1 18 0 0 18 18 15 0 Tetratricopeptide repeat BTAD PF03704.17 RKP04257.1 - 1.5 9.2 33.9 0.1 13.0 2.6 7.1 6 2 1 7 7 7 0 Bacterial transcriptional activator domain Arm PF00514.23 RKP04258.1 - 0.0052 16.8 19.3 0.082 13.0 0.4 6.1 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 RKP04258.1 - 0.34 11.3 7.1 7.5 7.1 0.3 5.1 4 0 0 4 4 4 0 HEAT repeat Ribosomal_S3_C PF00189.20 RKP04259.1 - 1.4e-24 86.4 3.3 6.9e-24 84.2 0.8 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 RKP04259.1 - 2.5e-09 36.8 0.1 4.5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 KH domain UPF0180 PF03698.13 RKP04259.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) EF-hand_1 PF00036.32 RKP04260.1 - 1.7e-42 139.8 11.1 4.3e-10 38.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKP04260.1 - 1e-36 125.2 2.1 2.8e-19 69.3 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RKP04260.1 - 8.5e-33 112.0 10.7 3.8e-15 55.5 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RKP04260.1 - 5.8e-31 103.8 5.3 2.3e-09 36.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RKP04260.1 - 5.3e-28 95.3 7.7 1.6e-06 27.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RKP04260.1 - 1e-15 57.8 0.1 3.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RKP04260.1 - 1.4e-10 41.1 0.5 3.1e-05 23.9 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RKP04260.1 - 1.8e-08 34.7 0.0 0.00062 20.1 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 RKP04260.1 - 2.7e-06 28.2 0.0 0.00032 21.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 RKP04260.1 - 6.7e-05 22.8 0.0 0.19 11.8 0.0 2.9 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 RKP04260.1 - 0.00014 21.9 1.2 0.00036 20.6 0.1 2.2 3 1 0 3 3 2 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 RKP04260.1 - 0.00065 20.4 0.3 1.5 9.7 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF1103 PF06513.11 RKP04260.1 - 0.001 18.7 3.8 0.0012 18.5 3.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Dockerin_1 PF00404.18 RKP04260.1 - 0.0011 19.1 5.8 0.022 14.9 0.4 3.2 1 1 3 4 4 4 1 Dockerin type I domain Caleosin PF05042.13 RKP04260.1 - 0.0027 17.7 1.0 2.3 8.1 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 RKP04260.1 - 0.0051 16.8 0.7 2 8.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Poly_export PF02563.16 RKP04260.1 - 0.0079 16.4 0.1 0.61 10.4 0.0 2.8 1 1 1 3 3 3 1 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 RKP04260.1 - 0.0082 14.7 0.0 0.0082 14.7 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 RKP04260.1 - 0.0087 16.4 0.4 1.7 9.0 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF4497 PF14924.6 RKP04260.1 - 0.014 15.9 0.0 0.5 10.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) MotA_activ PF09114.10 RKP04260.1 - 0.02 15.0 0.5 0.35 11.0 0.1 2.4 1 1 0 2 2 2 0 Transcription factor MotA, activation domain EF-hand_14 PF17959.1 RKP04260.1 - 0.025 14.9 0.1 6.2 7.2 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF2267 PF10025.9 RKP04260.1 - 0.036 14.4 0.0 0.17 12.2 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) SurA_N_2 PF13623.6 RKP04260.1 - 0.1 12.4 0.6 0.46 10.3 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain TetR_C_7 PF14246.6 RKP04260.1 - 0.12 12.4 0.0 11 6.1 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 RKP04260.1 - 0.16 12.5 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain ketoacyl-synt PF00109.26 RKP04261.1 - 4.5e-47 160.8 9.8 2.4e-46 158.3 7.1 2.5 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 RKP04261.1 - 6.9e-28 97.0 1.1 1.2e-27 96.2 1.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 RKP04261.1 - 0.00035 20.0 0.1 0.00062 19.2 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Casein_kappa PF00997.18 RKP04263.1 - 0.17 11.9 1.2 0.2 11.7 1.2 1.2 1 0 0 1 1 1 0 Kappa casein AAA PF00004.29 RKP04266.1 - 2.3e-12 47.5 0.0 4.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 RKP04266.1 - 1.8e-07 31.3 0.0 1.2e-05 25.3 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 RKP04266.1 - 3.1e-06 27.0 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RKP04266.1 - 4.5e-05 23.5 0.0 0.00011 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 RKP04266.1 - 6.2e-05 22.4 0.2 0.00011 21.6 0.0 1.4 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 RKP04266.1 - 0.00015 21.8 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKP04266.1 - 0.00029 21.2 0.3 0.0035 17.7 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 RKP04266.1 - 0.00084 19.0 2.6 0.0023 17.5 0.1 2.5 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 RKP04266.1 - 0.0012 19.3 0.5 0.0021 18.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 RKP04266.1 - 0.0013 19.0 0.1 0.058 13.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 RKP04266.1 - 0.0022 18.1 3.5 0.0025 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RKP04266.1 - 0.0039 16.9 0.9 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 RKP04266.1 - 0.0071 16.6 0.6 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RKP04266.1 - 0.0099 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 RKP04266.1 - 0.014 15.8 0.2 0.038 14.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 RKP04266.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 RKP04266.1 - 0.017 15.1 0.1 0.08 12.9 0.0 2.0 1 1 1 2 2 2 0 NTPase AAA_17 PF13207.6 RKP04266.1 - 0.025 15.0 0.1 0.061 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKP04266.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DS PF01916.17 RKP04266.1 - 0.06 12.6 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Deoxyhypusine synthase DEAD PF00270.29 RKP04266.1 - 0.064 13.0 0.0 4.5 7.0 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase Polyoma_lg_T_C PF06431.11 RKP04266.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Mg_chelatase PF01078.21 RKP04266.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RKP04266.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 RKP04266.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 RKP04266.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain HSP20 PF00011.21 RKP04267.1 - 3.2e-10 40.1 0.2 1.9e-06 28.0 0.0 2.3 1 1 1 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.16 RKP04267.1 - 0.057 14.4 0.1 0.17 12.9 0.1 1.8 1 1 0 1 1 1 0 CS domain HSP20 PF00011.21 RKP04268.1 - 8.5e-09 35.5 0.0 1.1e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 RKP04268.1 - 0.033 15.2 0.0 0.048 14.7 0.0 1.3 1 1 0 1 1 1 0 CS domain HhH-GPD PF00730.25 RKP04269.1 - 2.1e-20 73.2 0.0 6.8e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RKP04269.1 - 0.00013 21.7 0.0 0.00036 20.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 RKP04269.1 - 0.13 12.6 3.6 0.41 11.0 3.6 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III SPA PF08616.10 RKP04270.1 - 2.5e-09 37.1 0.0 5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Bud13 PF09736.9 RKP04271.1 - 2.6e-32 112.2 0.1 5.7e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex DHHC PF01529.20 RKP04272.1 - 3.9e-26 91.7 4.9 3.9e-26 91.7 4.9 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase GLTT PF01744.20 RKP04272.1 - 0.062 13.1 1.2 0.17 11.7 0.2 2.3 2 0 0 2 2 2 0 GLTT repeat (6 copies) WD40 PF00400.32 RKP04273.1 - 2e-08 34.8 0.0 0.0059 17.4 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat RNA_pol_Rbc25 PF08292.12 RKP04274.1 - 2.2e-28 99.1 0.0 3.7e-27 95.1 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 RKP04274.1 - 1.3e-10 41.5 0.1 2.1e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FAD_binding_1 PF00667.20 RKP04275.1 - 1.1e-27 97.1 0.0 2.5e-27 95.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 RKP04275.1 - 5.6e-19 68.8 0.0 1.2e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 RKP04275.1 - 7.1e-08 33.1 0.0 1.6e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Lipase_3 PF01764.25 RKP04277.1 - 3.7e-13 49.6 0.0 9.9e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) CBP PF12192.8 RKP04277.1 - 0.031 14.5 4.8 0.17 12.1 4.8 2.3 1 0 0 1 1 1 0 Fungal calcium binding protein PBP1_TM PF14812.6 RKP04279.1 - 1.9 8.9 5.4 5.2 7.5 5.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hydrophobin PF01185.18 RKP04280.1 - 4.3e-07 30.5 11.8 6.2e-07 30.0 11.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin LRR_6 PF13516.6 RKP04281.1 - 4.4e-08 32.6 2.1 0.014 15.4 0.0 4.3 5 0 0 5 5 5 3 Leucine Rich repeat Endonuc-BsobI PF09194.10 RKP04281.1 - 0.033 13.4 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI SOBP PF15279.6 RKP04281.1 - 0.19 12.3 15.0 0.28 11.8 15.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DIOX_N PF14226.6 RKP04282.1 - 7.3e-28 97.7 0.0 1.1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RKP04282.1 - 6.1e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Foie-gras_1 PF11817.8 RKP04283.1 - 0.012 15.2 0.0 0.041 13.5 0.0 1.9 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_7 PF13176.6 RKP04283.1 - 0.028 14.4 0.0 0.15 12.2 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RKP04283.1 - 0.047 14.5 0.0 0.047 14.5 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKP04283.1 - 0.079 13.1 0.0 0.35 11.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Sod_Cu PF00080.20 RKP04284.1 - 2.6e-50 170.3 6.6 3e-50 170.1 6.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BppL_N PF18338.1 RKP04284.1 - 0.016 15.0 0.9 0.21 11.4 0.1 3.0 3 0 0 3 3 3 0 Lower baseplate protein N-terminal domain Big_3_5 PF16640.5 RKP04284.1 - 0.78 10.0 6.6 2.1 8.6 3.1 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) zf-U1 PF06220.12 RKP04285.1 - 5.1e-20 70.9 4.8 7.8e-20 70.4 4.8 1.3 1 0 0 1 1 1 1 U1 zinc finger PPR_2 PF13041.6 RKP04286.1 - 0.03 14.5 0.0 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family Peptidase_M16 PF00675.20 RKP04286.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) PPR_3 PF13812.6 RKP04286.1 - 0.15 12.1 0.0 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF5427 PF10310.9 RKP04288.1 - 8.8e-07 28.2 3.0 1.3e-06 27.7 3.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 RKP04288.1 - 2.9 6.5 5.0 4.5 5.8 5.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pam17 PF08566.10 RKP04290.1 - 1e-40 139.3 0.1 1.1e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Radical_SAM PF04055.21 RKP04290.1 - 0.17 12.2 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Radical SAM superfamily Pkinase PF00069.25 RKP04291.1 - 7.9e-48 163.1 0.0 4.8e-32 111.4 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RKP04291.1 - 1.2e-34 119.7 0.0 1.4e-32 113.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKP04291.1 - 0.0078 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKP04291.1 - 0.017 15.1 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2_aberr PF17017.5 RKP04292.1 - 0.0073 16.5 6.6 0.0083 16.3 1.2 2.1 2 0 0 2 2 2 1 Aberrant zinc-finger Toxin_8 PF07365.12 RKP04292.1 - 1 9.6 4.2 0.4 10.9 0.4 2.3 2 0 0 2 2 2 0 Alpha conotoxin precursor GTP_EFTU PF00009.27 RKP04293.1 - 2.2e-59 200.3 0.0 3.2e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 RKP04293.1 - 3.4e-13 49.4 0.0 8.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKP04293.1 - 8.7e-09 35.7 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 RKP04293.1 - 7.8e-07 29.1 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 RKP04293.1 - 5.8e-05 22.9 0.0 0.00034 20.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 RKP04293.1 - 0.0089 16.1 0.1 0.038 14.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DnaJ PF00226.31 RKP04294.1 - 5.8e-18 64.8 0.0 1.2e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DDE_1 PF03184.19 RKP04294.1 - 0.092 12.4 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Enkurin PF13864.6 RKP04295.1 - 6.5e-14 52.2 0.1 1.3e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Calmodulin-binding LSM PF01423.22 RKP04297.1 - 2.4e-15 55.9 0.1 2.9e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKP04297.1 - 1.3e-05 25.3 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain ADPRTs_Tse2 PF18648.1 RKP04297.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Fer2_3 PF13085.6 RKP04298.1 - 6e-33 113.1 0.0 9e-33 112.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 RKP04298.1 - 5.1e-10 39.7 3.6 5.1e-10 39.7 3.6 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 RKP04298.1 - 7.7e-07 29.1 2.8 7.7e-07 29.1 2.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 RKP04298.1 - 1.7e-06 28.4 10.3 3.6e-06 27.3 7.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 RKP04298.1 - 0.0079 16.1 0.3 0.0079 16.1 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 RKP04298.1 - 0.18 12.0 12.1 0.093 12.9 7.5 2.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 RKP04298.1 - 5.7 7.6 17.7 0.42 11.2 10.2 2.7 2 2 1 3 3 3 0 4Fe-4S dicluster domain SF1-HH PF16275.5 RKP04299.1 - 6.7e-30 103.7 0.4 6.7e-30 103.7 0.4 1.7 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 RKP04299.1 - 9.9e-07 28.6 5.9 0.003 17.5 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 RKP04299.1 - 1.6e-05 24.6 0.2 3e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 RKP04299.1 - 0.022 14.6 0.8 0.022 14.6 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 RKP04299.1 - 0.023 14.7 2.8 0.23 11.4 0.2 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 RKP04299.1 - 0.046 13.5 6.7 0.11 12.3 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 RKP04299.1 - 0.054 13.8 0.4 0.12 12.7 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Caudo_TAP PF02413.17 RKP04299.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Fringe PF02434.16 RKP04300.1 - 6.1e-13 48.8 0.0 9.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 RKP04300.1 - 6.8e-10 38.8 0.2 1.3e-09 37.8 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF604 PAN_4 PF14295.6 RKP04300.1 - 1e-08 34.9 0.8 1e-08 34.9 0.8 2.5 3 0 0 3 3 3 1 PAN domain Galactosyl_T PF01762.21 RKP04300.1 - 0.00025 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase PAN_1 PF00024.26 RKP04300.1 - 0.003 17.5 0.1 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 RKP04300.1 - 0.0056 16.8 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_3 PF08277.12 RKP04300.1 - 0.059 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain Ank_2 PF12796.7 RKP04301.1 - 0.00081 19.9 1.1 0.043 14.4 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 RKP04301.1 - 0.0032 17.8 0.2 0.0089 16.4 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeat Methyltransf_25 PF13649.6 RKP04301.1 - 0.015 16.0 0.6 0.053 14.2 0.0 2.3 4 0 0 4 4 4 0 Methyltransferase domain Ank_5 PF13857.6 RKP04301.1 - 0.022 15.1 0.4 0.081 13.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Thr_dehydrat_C PF00585.18 RKP04301.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Ank_3 PF13606.6 RKP04301.1 - 0.035 14.6 0.0 0.14 12.8 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 RKP04301.1 - 0.1 13.2 0.1 0.66 10.6 0.0 2.3 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Glycos_transf_4 PF00953.21 RKP04302.1 - 3.3e-34 118.2 14.1 6.3e-34 117.3 14.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 GAS PF13851.6 RKP04303.1 - 3 7.2 4.8 10 5.4 4.9 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FAM176 PF14851.6 RKP04303.1 - 3.5 7.3 7.6 0.7 9.6 1.6 2.5 2 0 0 2 2 2 0 FAM176 family Response_reg PF00072.24 RKP04304.1 - 1.9e-10 40.9 0.1 1.4e-05 25.2 0.0 3.2 3 0 0 3 3 3 2 Response regulator receiver domain BUD22 PF09073.10 RKP04304.1 - 0.18 11.1 3.5 0.36 10.1 3.5 1.4 1 0 0 1 1 1 0 BUD22 ANAPC4_WD40 PF12894.7 RKP04305.1 - 1.8e-13 50.6 0.0 0.025 14.9 0.0 5.3 5 1 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKP04305.1 - 1.9e-08 34.8 2.7 1.7 9.6 0.1 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.12 RKP04305.1 - 0.14 12.2 0.3 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SR-25 PF10500.9 RKP04306.1 - 0.0048 16.5 11.3 0.0048 16.5 11.3 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 RKP04306.1 - 0.14 11.9 4.1 0.32 10.7 4.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IMUP PF15761.5 RKP04306.1 - 8.3 7.2 18.5 2.3 8.9 11.4 3.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein Spindle_Spc25 PF08234.12 RKP04307.1 - 3.1e-23 81.7 0.0 5.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 SPARC_Ca_bdg PF10591.9 RKP04307.1 - 2.9 8.2 6.8 11 6.4 6.8 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Presenilin PF01080.17 RKP04307.1 - 7.9 5.1 6.3 10 4.8 6.3 1.1 1 0 0 1 1 1 0 Presenilin Telomere_reg-2 PF10193.9 RKP04308.1 - 2.7e-19 69.6 1.2 5.4e-19 68.6 1.2 1.6 1 0 0 1 1 1 1 Telomere length regulation protein Dopey_N PF04118.14 RKP04310.1 - 7.9e-91 304.4 0.0 1.3e-90 303.7 0.0 1.3 1 0 0 1 1 1 1 Dopey, N-terminal CENP-B_dimeris PF09026.10 RKP04310.1 - 2.5 8.5 9.6 6.5 7.2 9.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 RKP04310.1 - 8.7 6.0 8.1 18 5.0 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF155 PF02582.14 RKP04311.1 - 1.4e-56 191.4 0.1 2e-56 190.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PRANC PF09372.10 RKP04311.1 - 0.033 14.5 2.8 0.19 12.1 0.4 2.6 1 1 1 2 2 2 0 PRANC domain DUF434 PF04256.12 RKP04311.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Prenyltrans PF00432.21 RKP04312.1 - 6.9e-40 134.5 12.1 6.1e-08 32.3 0.0 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 RKP04312.1 - 0.067 12.3 0.0 37 3.3 0.0 3.1 2 1 1 3 3 3 0 Squalene-hopene cyclase C-terminal domain CAF1C_H4-bd PF12265.8 RKP04313.1 - 2e-26 92.0 0.5 4.5e-26 90.9 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 RKP04313.1 - 3.5e-25 87.8 8.3 6e-05 23.7 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP04313.1 - 0.0023 18.2 1.4 0.14 12.5 0.0 3.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKP04313.1 - 0.0055 16.6 0.4 0.04 13.8 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Rad60-SLD PF11976.8 RKP04314.1 - 1.7e-06 27.7 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Herpes_capsid PF06112.11 RKP04314.1 - 0.0092 16.1 1.4 0.0092 16.1 1.4 4.3 3 1 2 5 5 5 1 Gammaherpesvirus capsid protein PDZ_2 PF13180.6 RKP04314.1 - 0.012 15.9 0.1 0.055 13.8 0.1 2.1 1 0 0 1 1 1 0 PDZ domain ubiquitin PF00240.23 RKP04314.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family CDP-OH_P_transf PF01066.21 RKP04315.1 - 2e-10 41.3 3.0 2.5e-10 41.0 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RasGEF PF00617.19 RKP04316.1 - 1.6e-32 113.2 0.0 2.5e-32 112.5 0.0 1.3 2 0 0 2 2 2 1 RasGEF domain DUF2431 PF10354.9 RKP04317.1 - 1.5e-48 165.2 0.0 1.8e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ICMT PF04140.14 RKP04318.1 - 6e-20 71.5 0.4 1.4e-19 70.3 0.4 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 RKP04318.1 - 8.2e-07 29.4 0.2 8.2e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase Proteasom_Rpn13 PF04683.13 RKP04319.1 - 1.9e-20 73.2 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SET PF00856.28 RKP04320.1 - 8.4e-19 68.6 0.2 9e-18 65.2 0.2 2.0 1 1 0 1 1 1 1 SET domain AWS PF17907.1 RKP04320.1 - 4e-08 33.2 9.0 4e-08 33.2 9.0 1.7 2 0 0 2 2 2 1 AWS domain Nab2p_Zf1 PF18260.1 RKP04320.1 - 0.33 10.9 3.1 0.61 10.0 3.1 1.4 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Cupin_8 PF13621.6 RKP04321.1 - 4e-30 105.4 0.0 6.3e-30 104.7 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 RKP04321.1 - 0.12 11.8 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein Phage_holin_3_2 PF04550.12 RKP04323.1 - 0.00026 21.5 0.1 0.0044 17.5 0.0 2.1 1 1 1 2 2 2 1 Phage holin family 2 DUF4536 PF15055.6 RKP04323.1 - 0.0012 19.1 5.0 0.0062 16.7 5.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) SNARE PF05739.19 RKP04324.1 - 2.4e-11 43.4 0.9 4.4e-11 42.6 0.2 1.7 2 0 0 2 2 2 1 SNARE domain Tup_N PF08581.10 RKP04324.1 - 0.057 13.7 0.6 1.1 9.6 0.3 2.7 2 0 0 2 2 2 0 Tup N-terminal Syntaxin-5_N PF11416.8 RKP04324.1 - 0.18 11.1 2.6 0.38 10.0 0.3 2.7 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 RKP04324.1 - 1 9.0 4.6 5.8 6.5 0.1 3.2 2 1 0 3 3 3 0 Syntaxin BLOC1_2 PF10046.9 RKP04324.1 - 1.1 9.7 4.5 5 7.5 0.1 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 RKP04324.1 - 2.5 8.2 7.0 9.3 6.3 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.32 RKP04326.1 - 2e-19 69.6 0.2 4.5e-09 36.8 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP04326.1 - 3.9e-10 39.9 0.2 4.9e-06 26.7 0.0 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKP04326.1 - 0.0021 16.8 0.0 0.0039 15.9 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RKP04326.1 - 0.019 13.7 0.0 1.4 7.5 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like DUF4920 PF16267.5 RKP04326.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) WD40_like PF17005.5 RKP04326.1 - 0.044 13.1 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Frtz PF11768.8 RKP04326.1 - 0.062 11.6 0.0 0.11 10.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 RKP04326.1 - 0.087 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Med23 PF11573.8 RKP04326.1 - 0.15 9.7 0.0 0.18 9.4 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 Herpes_US9 PF06072.11 RKP04328.1 - 0.026 14.4 1.6 0.086 12.7 1.6 1.9 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SNase PF00565.17 RKP04329.1 - 1.6e-22 80.0 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue YjeF_N PF03853.15 RKP04331.1 - 2.7e-26 92.5 0.0 5.4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus Meth_synt_2 PF01717.18 RKP04332.1 - 1.5e-150 500.9 0.0 3.4e-143 476.8 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 RKP04332.1 - 8.1e-108 360.6 0.0 8.4e-101 337.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain GBP PF02263.19 RKP04334.1 - 0.0099 15.2 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Tropomyosin_1 PF12718.7 RKP04334.1 - 0.098 12.8 1.7 0.14 12.3 0.6 1.8 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.11 RKP04334.1 - 0.1 11.5 0.4 0.27 10.1 0.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein AXE1 PF05448.12 RKP04334.1 - 0.21 10.2 0.1 0.33 9.6 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) WD40 PF00400.32 RKP04335.1 - 4.1e-15 55.9 7.5 9.4e-05 23.1 0.1 8.2 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKP04335.1 - 7.2e-06 26.2 0.9 0.14 12.5 0.1 5.7 4 3 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKP04335.1 - 0.037 13.9 0.1 5.9 6.7 0.0 3.2 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A dCMP_cyt_deam_1 PF00383.23 RKP04336.1 - 2.2e-24 85.2 3.9 3.5e-24 84.6 3.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RKP04336.1 - 8.1e-11 41.8 0.3 1.8e-10 40.7 0.3 1.5 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 RKP04336.1 - 0.022 14.7 1.2 0.036 13.9 1.2 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain SNAD4 PF18750.1 RKP04336.1 - 0.093 12.9 0.4 0.17 12.0 0.4 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 EB1 PF03271.17 RKP04337.1 - 3.8e-12 46.3 0.0 7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 RKP04337.1 - 5.6e-06 26.5 0.2 9.4e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Ustilago_mating PF05722.12 RKP04337.1 - 0.093 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein ELFV_dehydrog PF00208.21 RKP04338.1 - 2.6e-52 178.0 0.0 4.1e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 RKP04338.1 - 3.9e-26 91.0 0.0 2.9e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 RKP04338.1 - 0.026 14.4 0.0 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glyco_hydro_114 PF03537.13 RKP04338.1 - 0.05 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Ank_2 PF12796.7 RKP04340.1 - 0.00028 21.4 0.1 0.001 19.6 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) RRM_1 PF00076.22 RKP04341.1 - 1.4e-13 50.4 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKP04341.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Ribosomal_L22e PF01776.17 RKP04342.1 - 4e-39 133.4 1.1 5e-39 133.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family ASD2 PF08687.11 RKP04343.1 - 0.078 12.5 1.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 CENP-F_leu_zip PF10473.9 RKP04343.1 - 0.18 11.9 2.2 0.45 10.5 0.3 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.13 RKP04343.1 - 0.38 10.8 2.3 1.5 9.0 2.3 1.9 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 RKP04343.1 - 0.68 10.6 0.0 0.68 10.6 0.0 5.9 5 1 1 6 6 6 0 SlyX DUF563 PF04577.14 RKP04344.1 - 1.1e-30 107.4 0.0 1.9e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Cofilin_ADF PF00241.20 RKP04345.1 - 8.9e-25 86.8 0.0 1.1e-12 47.8 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein RNase_PH PF01138.21 RKP04346.1 - 1.5e-19 70.8 0.1 2.7e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RKP04346.1 - 0.0022 18.0 0.0 0.0066 16.5 0.0 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MDM31_MDM32 PF08118.11 RKP04347.1 - 6.4e-134 447.5 0.0 7.2e-134 447.3 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4112 PF13430.6 RKP04349.1 - 1.9e-09 37.7 0.1 2.8e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) E1-E2_ATPase PF00122.20 RKP04350.1 - 3e-29 101.8 0.6 3e-29 101.8 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RKP04350.1 - 4.4e-17 63.1 0.0 2.6e-10 40.9 0.0 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKP04350.1 - 0.00046 20.2 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKP04350.1 - 0.017 14.9 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase COX16 PF14138.6 RKP04351.1 - 6.1e-08 33.1 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 YuzL PF14115.6 RKP04351.1 - 0.015 15.7 0.8 0.036 14.5 0.8 1.6 1 0 0 1 1 1 0 YuzL-like protein Trp_halogenase PF04820.14 RKP04351.1 - 0.05 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Herpes_capsid PF06112.11 RKP04351.1 - 7.4 6.6 11.9 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein FAM199X PF15814.5 RKP04351.1 - 8.6 5.3 6.2 14 4.6 6.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X ABC1 PF03109.16 RKP04352.1 - 1e-28 99.9 0.0 1.7e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 RKP04352.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_L13 PF00572.18 RKP04353.1 - 2.4e-07 31.0 0.3 3.9e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 SBDS PF01172.18 RKP04355.1 - 1.3e-07 31.6 0.0 2e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Hist_deacetyl PF00850.19 RKP04356.1 - 1.4e-78 264.5 0.0 1.8e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SGP PF17228.2 RKP04356.1 - 0.11 13.3 0.2 0.34 11.8 0.2 1.8 1 0 0 1 1 1 0 Sulphur globule protein DUF1769 PF08588.10 RKP04357.1 - 6.6e-13 48.6 0.1 1.2e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr1/GCA_003615045.1_Caupr1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr1/GCA_003615045.1_Caupr1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr1/GCA_003615045.1_Caupr1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr1/GCA_003615045.1_Caupr1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 17:01:56 2019 # [ok]