# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PHtD_u1 PF16645.5 EGF75801.1 - 0.023 15.1 0.6 0.053 13.9 0.6 1.7 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein Fucose_iso_N2 PF07882.12 EGF75801.1 - 0.24 11.0 1.7 0.4 10.2 1.7 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain FCD PF07729.12 EGF75804.1 - 4e-26 91.9 0.1 5.1e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EGF75804.1 - 5e-06 26.1 0.6 3.1e-05 23.5 0.1 2.5 2 1 1 3 3 3 1 Bacterial regulatory proteins, gntR family DUF1966 PF09260.11 EGF75804.1 - 0.029 14.6 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) DUF2018 PF09442.10 EGF75804.1 - 0.047 14.7 3.6 0.05 14.6 0.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) Fe_dep_repress PF01325.19 EGF75804.1 - 0.048 13.9 0.9 0.21 11.8 0.1 2.4 2 1 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain DUF3750 PF12570.8 EGF75804.1 - 0.092 13.4 0.0 0.15 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3750) HTH_46 PF15977.5 EGF75804.1 - 0.36 10.9 2.3 0.7 9.9 0.1 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding TctC PF03401.14 EGF75805.1 - 1.9e-28 99.3 0.0 2.8e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor DUF1932 PF09130.11 EGF75805.1 - 1.5e-13 50.5 0.0 3.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 EGF75805.1 - 2.5e-06 27.8 0.1 9.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGF75805.1 - 0.00066 20.2 0.9 0.0039 17.7 0.4 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGF75805.1 - 0.015 15.4 0.1 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Nucleic_acid_bd PF13820.6 EGF75805.1 - 0.051 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Putative nucleic acid-binding region PDH PF02153.17 EGF75805.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase TctA PF01970.16 EGF75806.1 - 3.3e-23 82.1 3.8 3.8e-23 81.9 3.8 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family DUF5325 PF17259.2 EGF75806.1 - 1.5 8.7 4.5 0.3 11.0 0.3 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5325) Peptidase_S41 PF03572.18 EGF75807.1 - 1.8e-13 50.4 0.0 3.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_4 PF17816.1 EGF75807.1 - 0.064 13.6 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 PDZ domain DNA_pol3_beta_2 PF02767.16 EGF75807.1 - 0.11 12.7 0.2 0.76 10.0 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain PDZ PF00595.24 EGF75807.1 - 0.17 12.3 0.0 0.77 10.2 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 EGF75808.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 PDZ domain FtsX PF02687.21 EGF75809.1 - 6.8e-12 45.7 10.4 1.4e-09 38.3 1.3 6.0 5 1 1 6 6 6 2 FtsX-like permease family T6SS_VipA PF05591.12 EGF75809.1 - 0.074 12.9 0.2 0.24 11.2 0.2 1.8 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 TetR_N PF00440.23 EGF75810.1 - 1.2e-07 31.4 0.0 2.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_40 PF14493.6 EGF75810.1 - 0.015 15.7 0.5 1.2 9.7 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Chitin_bind_1 PF00187.19 EGF75811.1 - 0.25 11.9 6.1 0.41 11.2 6.0 1.5 1 1 0 1 1 1 0 Chitin recognition protein Tyrosinase PF00264.20 EGF75812.1 - 2e-35 123.1 7.1 2.4e-18 67.2 0.2 2.1 1 1 1 2 2 2 2 Common central domain of tyrosinase Band_7_1 PF13421.6 EGF75813.1 - 3.1e-46 157.7 0.2 4.4e-46 157.3 0.2 1.1 1 0 0 1 1 1 1 SPFH domain-Band 7 family zf-ribbon_3 PF13248.6 EGF75813.1 - 1.4e-07 30.7 5.8 2.4e-07 29.9 5.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EGF75813.1 - 6.8e-05 22.4 9.4 0.00015 21.4 9.4 1.6 1 1 0 1 1 1 1 zinc-ribbon domain Band_7 PF01145.25 EGF75813.1 - 0.00019 21.5 0.4 0.00035 20.6 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family DZR PF12773.7 EGF75813.1 - 0.00028 20.9 2.8 0.00047 20.1 2.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGF75813.1 - 0.01 16.6 1.9 0.018 15.8 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon family zinc-ribbons_6 PF07191.12 EGF75813.1 - 0.011 15.6 1.6 0.018 15.0 1.6 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-NADH-PPase PF09297.11 EGF75813.1 - 0.017 14.8 2.1 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EGF75813.1 - 0.033 14.1 5.5 1.4 8.9 0.4 2.3 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 EGF75813.1 - 0.12 11.9 3.1 0.28 10.7 3.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1272 PF06906.11 EGF75813.1 - 0.13 12.3 3.5 0.24 11.5 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Ribosomal_L32p PF01783.23 EGF75813.1 - 0.25 11.6 2.0 0.53 10.6 2.0 1.6 1 1 0 1 1 1 0 Ribosomal L32p protein family zf-FPG_IleRS PF06827.14 EGF75813.1 - 0.3 11.0 1.8 8.9 6.3 0.3 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS GFA PF04828.14 EGF75813.1 - 0.56 10.6 3.9 2.1 8.7 0.3 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.10 EGF75813.1 - 0.6 10.3 4.5 3.4 7.8 0.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.14 EGF75813.1 - 0.72 9.9 2.5 9 6.4 0.5 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-ISL3 PF14690.6 EGF75813.1 - 2.7 8.7 6.3 13 6.6 0.4 2.4 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 NOB1_Zn_bind PF08772.11 EGF75813.1 - 3 8.1 8.6 12 6.1 1.1 2.7 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF1610 PF07754.11 EGF75813.1 - 4.2 7.4 13.1 4.4 7.4 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) YtzH PF14165.6 EGF75814.1 - 1.6e-31 108.5 3.1 1.9e-31 108.3 3.1 1.0 1 0 0 1 1 1 1 YtzH-like protein MetOD2 PF18548.1 EGF75814.1 - 0.05 13.7 0.4 1.5 8.9 0.1 2.0 1 1 1 2 2 2 0 Metanogen output domain 2 DUF5069 PF16798.5 EGF75814.1 - 0.064 13.5 0.0 0.072 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) MRP-S27 PF10037.9 EGF75814.1 - 0.072 11.9 0.1 0.087 11.7 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Methyltransf_4 PF02390.17 EGF75815.1 - 1.4e-47 161.4 0.0 1.7e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EGF75815.1 - 2.1e-07 30.9 0.1 3.1e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF75815.1 - 1.1e-06 29.2 0.0 1.7e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF75815.1 - 5.3e-06 27.1 0.0 1.1e-05 26.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF75815.1 - 0.0009 19.8 0.0 0.0014 19.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGF75815.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGF75815.1 - 0.003 17.4 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TssO PF17561.2 EGF75815.1 - 0.0031 17.6 0.4 0.0049 17.0 0.1 1.4 2 0 0 2 2 2 1 Type VI secretion system, TssO MTS PF05175.14 EGF75815.1 - 0.0033 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 EGF75815.1 - 0.0035 16.4 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.18 EGF75815.1 - 0.032 13.9 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.19 EGF75815.1 - 0.078 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Transp_cyt_pur PF02133.15 EGF75816.1 - 1.7e-05 23.8 8.5 2.8e-05 23.1 8.4 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3093 PF11292.8 EGF75816.1 - 0.17 12.1 8.8 7.3 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) SLATT_4 PF18186.1 EGF75816.1 - 0.19 11.4 1.1 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 DHHC PF01529.20 EGF75816.1 - 1.9 8.6 7.1 0.56 10.3 1.8 2.5 1 1 2 3 3 3 0 DHHC palmitoyltransferase B12D PF06522.11 EGF75816.1 - 2.7 7.8 5.6 1.6 8.5 0.3 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2516 PF10724.9 EGF75816.1 - 7.9 6.8 11.7 0.21 11.9 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) Glyoxalase PF00903.25 EGF75817.1 - 4.4e-06 26.9 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGF75817.1 - 1.7e-05 24.8 0.2 4.6e-05 23.3 0.2 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Acetyltransf_10 PF13673.7 EGF75817.1 - 0.071 13.0 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Hpr_kinase_C PF07475.12 EGF75818.1 - 7.4e-61 204.6 1.6 1.5e-60 203.6 0.1 2.1 2 1 1 3 3 3 1 HPr Serine kinase C-terminal domain Hpr_kinase_N PF02603.16 EGF75818.1 - 1.5e-37 128.4 0.0 2.4e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 HPr Serine kinase N terminus PhnA PF03831.14 EGF75818.1 - 1.2e-31 108.3 5.3 3e-31 107.1 5.3 1.7 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 EGF75818.1 - 3.7e-16 58.8 5.2 6.6e-16 58.0 5.2 1.4 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 EGF75818.1 - 0.0088 15.5 2.1 0.022 14.3 2.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 EGF75818.1 - 0.04 13.9 0.4 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DRTGG PF07085.12 EGF75818.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 DRTGG domain Prok-RING_1 PF14446.6 EGF75818.1 - 0.14 12.1 0.2 0.31 11.0 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.6 EGF75818.1 - 0.28 11.2 1.6 1.3 9.0 1.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Peptidase_S15 PF02129.18 EGF75819.1 - 1.7e-60 204.9 0.1 2.4e-60 204.4 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EGF75819.1 - 2.6e-47 161.7 0.0 5e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF3231 PF11553.8 EGF75819.1 - 9.2e-36 123.0 0.0 1.4e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) Peptidase_S9 PF00326.21 EGF75819.1 - 0.0096 15.4 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2383 PF09537.10 EGF75819.1 - 0.021 15.1 0.0 0.063 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) BPD_transp_1 PF00528.22 EGF75820.1 - 2.3e-23 82.9 17.2 2.7e-23 82.7 17.2 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF1700 PF08006.11 EGF75820.1 - 8.5 5.9 8.3 6.7 6.2 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) OpuAC PF04069.12 EGF75821.1 - 1.9e-26 93.2 0.0 2.1e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system DUF608 PF04685.13 EGF75821.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Aldose_epim PF01263.20 EGF75822.1 - 2.3e-48 165.1 0.0 3.3e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase PTS_EIIA_2 PF00359.22 EGF75822.1 - 9.4e-24 84.0 3.6 1e-11 45.0 0.1 3.6 2 1 2 4 4 4 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PRD PF00874.20 EGF75822.1 - 7.9e-22 77.4 8.6 8.1e-18 64.5 1.3 3.1 2 0 0 2 2 2 2 PRD domain Mga PF05043.13 EGF75822.1 - 1.3e-07 32.1 1.8 4.9e-06 27.0 0.4 3.7 2 1 1 3 3 3 1 Mga helix-turn-helix domain HTH_11 PF08279.12 EGF75822.1 - 0.015 15.3 0.0 0.045 13.7 0.0 1.9 1 0 0 1 1 1 0 HTH domain PuR_N PF09182.10 EGF75822.1 - 0.037 14.0 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal DUF3124 PF11322.8 EGF75822.1 - 0.086 13.0 0.0 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) Sigma70_r2 PF04542.14 EGF75823.1 - 3.5e-11 42.7 0.1 6.1e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 UPF0122 PF04297.14 EGF75823.1 - 2.1e-09 37.5 0.0 5.5e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.16 EGF75823.1 - 3.9e-08 32.7 0.0 8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EGF75823.1 - 3.1e-07 30.0 0.0 5.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 DUF1804 PF08822.11 EGF75823.1 - 0.0015 18.6 0.3 0.0027 17.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) GerE PF00196.19 EGF75823.1 - 0.0028 17.2 0.2 0.0052 16.3 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 EGF75823.1 - 0.02 15.0 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EGF75823.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Glyco_hydro_92N PF17678.1 EGF75824.1 - 1.6e-41 142.8 5.2 2.9e-41 141.9 5.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_92 PF07971.12 EGF75824.1 - 6.4e-33 114.4 0.4 1.4e-32 113.3 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 F5_F8_type_C PF00754.25 EGF75824.1 - 6.4e-08 32.8 1.5 2.6e-07 30.8 1.5 2.1 1 0 0 1 1 1 1 F5/8 type C domain LytR_cpsA_psr PF03816.14 EGF75825.1 - 7.8e-48 162.5 0.1 1.1e-47 162.1 0.1 1.2 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain Glyco_trans_2_3 PF13632.6 EGF75826.1 - 9.6e-19 68.1 1.8 9.6e-19 68.1 1.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGF75826.1 - 2.5e-17 63.2 0.0 6.1e-16 58.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGF75826.1 - 8.5e-12 45.4 0.0 1.8e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF75826.1 - 6.3e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGF75826.1 - 3.6e-07 29.9 0.5 0.00016 21.2 0.2 2.3 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 EGF75826.1 - 0.0013 17.4 8.5 0.013 14.2 6.0 2.2 2 0 0 2 2 2 2 Chitin synthase AAA_16 PF13191.6 EGF75827.1 - 3.1e-43 148.1 0.0 9e-43 146.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 EGF75827.1 - 4.8e-30 104.8 1.9 1e-29 103.7 1.9 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF75827.1 - 1.7e-21 76.7 0.2 3.1e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF75827.1 - 1.6e-07 30.9 0.1 2.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Trans_reg_C PF00486.28 EGF75827.1 - 3.7e-06 26.9 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal ATPase_2 PF01637.18 EGF75827.1 - 1.4e-05 25.2 0.1 0.00013 22.0 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EGF75827.1 - 0.00059 19.8 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGF75827.1 - 0.00077 19.7 0.0 0.0039 17.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGF75827.1 - 0.0016 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.15 EGF75827.1 - 0.011 15.7 0.2 0.046 13.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 EGF75827.1 - 0.013 15.9 0.1 0.17 12.3 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGF75827.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 EGF75827.1 - 0.025 14.5 0.7 0.07 13.0 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EGF75827.1 - 0.037 14.1 0.7 0.44 10.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain TPR_2 PF07719.17 EGF75827.1 - 0.039 14.1 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2791 PF10923.8 EGF75827.1 - 0.047 12.5 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_7 PF12775.7 EGF75827.1 - 0.072 12.6 0.1 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGF75827.1 - 0.08 13.3 0.0 0.32 11.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGF75827.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 EGF75827.1 - 0.13 12.5 0.4 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.6 EGF75827.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain CN_hydrolase PF00795.22 EGF75828.1 - 4.3e-32 111.5 0.0 3.5e-31 108.5 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGF75828.1 - 1.1e-21 77.1 0.0 3.9e-21 75.3 0.0 1.8 1 1 0 1 1 1 1 NAD synthase LSM PF01423.22 EGF75829.1 - 5.3e-17 61.3 0.1 5.6e-17 61.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain RNase_3_N PF18497.1 EGF75830.1 - 0.0012 19.0 0.7 1 9.6 0.2 2.2 2 0 0 2 2 2 1 Ribonuclease III N-terminal domain PEP-utilisers_N PF05524.13 EGF75830.1 - 0.0027 17.8 4.7 1.4 9.1 0.1 2.9 2 1 1 3 3 3 2 PEP-utilising enzyme, N-terminal DHR10 PF18595.1 EGF75830.1 - 0.0032 17.5 14.6 0.067 13.3 1.8 2.7 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain YabA PF06156.13 EGF75830.1 - 0.0038 17.8 13.5 0.15 12.7 1.4 2.8 2 1 1 3 3 3 2 Initiation control protein YabA Phycobilisome PF00502.19 EGF75830.1 - 0.0061 16.5 1.1 1.3 9.0 0.2 2.1 2 0 0 2 2 2 1 Phycobilisome protein APG6_N PF17675.1 EGF75830.1 - 0.0078 16.8 18.2 0.1 13.1 7.6 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region Ntox28 PF15605.6 EGF75830.1 - 0.0092 16.2 9.2 0.51 10.6 0.8 2.5 2 1 0 2 2 2 2 Bacterial toxin 28 DUF4164 PF13747.6 EGF75830.1 - 0.011 16.0 7.4 0.82 10.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.19 EGF75830.1 - 0.012 13.6 4.4 0.015 13.3 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 EGF75830.1 - 0.012 15.8 6.5 0.26 11.5 0.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Gag_p30 PF02093.16 EGF75830.1 - 0.017 14.7 1.3 4 6.9 0.1 2.1 2 0 0 2 2 2 0 Gag P30 core shell protein Snapin_Pallidin PF14712.6 EGF75830.1 - 0.018 15.4 12.0 0.3 11.5 1.0 2.6 3 0 0 3 3 2 0 Snapin/Pallidin DUF4062 PF13271.6 EGF75830.1 - 0.042 14.2 0.0 12 6.4 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4062) DUF4407 PF14362.6 EGF75830.1 - 0.045 13.1 14.0 0.1 11.9 13.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SLATT_4 PF18186.1 EGF75830.1 - 0.048 13.3 6.2 1.6 8.4 0.8 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 ABC_tran_CTD PF16326.5 EGF75830.1 - 0.052 13.8 5.0 4 7.8 0.4 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 EGF75830.1 - 0.053 13.6 15.6 0.91 9.6 4.7 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus IL10 PF00726.17 EGF75830.1 - 0.064 12.8 5.6 12 5.4 0.2 3.4 1 1 2 3 3 3 0 Interleukin 10 RMI1_C PF16099.5 EGF75830.1 - 0.07 13.0 10.2 0.64 9.8 0.4 2.4 3 0 0 3 3 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold COG2 PF06148.11 EGF75830.1 - 0.1 12.7 2.9 4.9 7.2 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MCU PF04678.13 EGF75830.1 - 0.13 12.3 8.5 1.6 8.8 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Phage_GPO PF05929.11 EGF75830.1 - 0.16 11.5 14.5 1.1 8.9 2.7 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase BLOC1_2 PF10046.9 EGF75830.1 - 0.17 12.2 7.2 2.8 8.3 0.4 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CcdB PF01845.17 EGF75830.1 - 0.17 12.1 2.0 19 5.6 0.0 2.7 3 0 0 3 3 2 0 CcdB protein JIP_LZII PF16471.5 EGF75830.1 - 0.22 11.7 6.5 5.2 7.3 0.1 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Bcr-Abl_Oligo PF09036.10 EGF75830.1 - 0.23 11.5 2.2 16 5.6 0.1 2.5 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DotU PF09850.9 EGF75830.1 - 0.5 10.1 1.9 20 4.8 0.0 2.4 3 0 0 3 3 2 0 Type VI secretion system protein DotU DASH_Spc19 PF08287.11 EGF75830.1 - 0.55 10.1 20.4 1.8 8.4 5.4 2.3 1 1 1 2 2 2 0 Spc19 DivIVA PF05103.13 EGF75830.1 - 0.59 10.2 6.7 9.4 6.3 1.6 2.6 2 1 0 2 2 2 0 DivIVA protein DivIC PF04977.15 EGF75830.1 - 0.76 9.6 18.9 0.57 10.0 1.9 3.0 3 0 0 3 3 3 0 Septum formation initiator CD99L2 PF12301.8 EGF75830.1 - 1 9.7 20.1 5.3 7.3 1.4 2.9 1 1 2 3 3 3 0 CD99 antigen like protein 2 FliJ PF02050.16 EGF75830.1 - 1.1 9.5 12.1 3.6 7.8 1.1 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein IFT57 PF10498.9 EGF75830.1 - 1.1 8.2 11.4 2.4 7.0 2.8 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 EGF75830.1 - 1.2 9.2 17.2 13 5.9 6.2 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 EGF75830.1 - 1.3 7.1 17.8 3.3 5.7 17.9 1.6 1 1 0 1 1 1 0 HOOK protein Sulfatase_C PF14707.6 EGF75830.1 - 1.6 9.5 4.0 3.3 8.5 0.8 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Spc7 PF08317.11 EGF75830.1 - 1.7 7.5 15.8 0.26 10.1 11.9 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EGF75830.1 - 1.7 9.1 7.3 11 6.6 0.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EGF75830.1 - 1.8 8.8 17.3 2.3 8.5 2.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 EGF75830.1 - 1.9 7.3 6.5 2.7 6.8 6.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4446 PF14584.6 EGF75830.1 - 1.9 8.5 7.3 8.9 6.3 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) H-kinase_dim PF02895.14 EGF75830.1 - 2.4 8.6 6.6 75 3.8 6.1 2.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Fez1 PF06818.15 EGF75830.1 - 2.5 8.5 16.0 6.9 7.1 15.9 1.7 1 1 0 1 1 1 0 Fez1 tRNA-synt_1g PF09334.11 EGF75830.1 - 2.5 6.7 5.1 9.9 4.8 0.4 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (M) Med9 PF07544.13 EGF75830.1 - 4.5 7.4 15.1 1.8 8.7 0.9 2.8 3 1 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 PRKG1_interact PF15898.5 EGF75830.1 - 5.3 8.0 20.4 0.83 10.6 9.3 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain G-patch_2 PF12656.7 EGF75830.1 - 7.1 6.8 9.2 18 5.5 0.5 3.3 3 0 0 3 3 3 0 G-patch domain DUF2203 PF09969.9 EGF75830.1 - 9 7.0 12.1 8.6 7.1 1.0 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) CENP-Q PF13094.6 EGF75832.1 - 0.85 9.8 11.8 0.86 9.8 10.9 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribonuc_P_40 PF08584.11 EGF75832.1 - 0.87 8.8 6.8 0.072 12.4 0.6 1.9 1 1 1 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit zf-C4H2 PF10146.9 EGF75832.1 - 1.9 8.7 9.9 2 8.7 8.9 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein LMBR1 PF04791.16 EGF75832.1 - 6.6 5.5 7.9 7.7 5.3 7.9 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein Urease_beta PF00699.20 EGF75834.1 - 4.5e-44 148.4 0.1 1.4e-42 143.7 0.0 2.1 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EGF75834.1 - 2.8e-40 136.6 0.3 8.2e-40 135.1 0.1 1.9 3 0 0 3 3 3 1 Urease, gamma subunit Amidohydro_1 PF01979.20 EGF75835.1 - 1.7e-75 254.5 1.9 2.5e-75 254.0 1.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGF75835.1 - 4.1e-51 172.4 5.5 9.4e-51 171.2 5.5 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 EGF75835.1 - 2.9e-10 40.2 6.2 2.8e-07 30.4 0.8 2.9 1 1 1 2 2 2 2 Amidohydrolase family PLDc_2 PF13091.6 EGF75835.1 - 0.099 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain UreF PF01730.16 EGF75836.1 - 2.2e-28 99.5 0.0 2.9e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 UreF UreE_N PF02814.15 EGF75836.1 - 3.5e-11 42.5 0.2 6.9e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain UreE_C PF05194.12 EGF75836.1 - 8e-07 29.5 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain UT PF03253.14 EGF75837.1 - 7.6e-33 113.9 13.5 8.9e-33 113.7 13.5 1.0 1 0 0 1 1 1 1 Urea transporter Clc-like PF07062.12 EGF75837.1 - 0.044 13.2 3.8 0.074 12.5 3.8 1.3 1 0 0 1 1 1 0 Clc-like MmgE_PrpD PF03972.14 EGF75838.1 - 1.2e-58 198.7 0.0 1.4e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF4197 PF13852.6 EGF75838.1 - 0.12 12.1 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4197) cIII PF08134.11 EGF75838.1 - 0.16 11.7 0.0 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 cIII protein family MmgE_PrpD PF03972.14 EGF75839.1 - 7.3e-141 469.7 1.1 8.6e-141 469.4 1.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Fumerase PF05681.14 EGF75840.1 - 1.3e-93 313.3 0.4 1.5e-93 313.2 0.4 1.0 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) BppU_IgG PF18667.1 EGF75840.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Baseplate upper protein immunoglobulin like domain Fumerase_C PF05683.12 EGF75841.1 - 5e-45 153.3 0.1 5.7e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Fumarase C-terminus Esterase PF00756.20 EGF75842.1 - 2.3e-21 76.6 0.7 2.6e-20 73.1 0.7 2.0 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGF75842.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGF75842.1 - 0.0011 18.5 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EGF75842.1 - 0.0052 16.6 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EGF75842.1 - 0.021 14.5 0.1 0.66 9.6 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 EGF75842.1 - 0.029 13.9 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Peripla_BP_3 PF13377.6 EGF75843.1 - 8.4e-37 127.1 0.0 3.4e-36 125.1 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EGF75843.1 - 4.4e-27 95.2 0.0 5.5e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EGF75843.1 - 4.5e-19 68.0 0.4 9e-19 67.0 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EGF75843.1 - 3e-18 66.4 0.1 3.1e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_10 PF04967.12 EGF75843.1 - 0.078 12.8 0.4 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain GFO_IDH_MocA PF01408.22 EGF75844.1 - 6e-21 75.5 0.5 9.7e-21 74.8 0.5 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGF75844.1 - 9.8e-07 28.8 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EGF75844.1 - 9.8e-05 23.0 0.2 0.00019 22.0 0.2 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGF75844.1 - 0.08 13.5 0.1 0.19 12.3 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BPD_transp_1 PF00528.22 EGF75845.1 - 7.4e-22 78.0 16.8 8.8e-22 77.7 16.8 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Cu-oxidase_2 PF07731.14 EGF75846.1 - 1.7e-21 76.4 0.1 3.1e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGF75846.1 - 7.3e-07 29.2 0.0 3.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGF75846.1 - 0.012 15.8 0.0 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Multicopper oxidase Aldedh PF00171.22 EGF75847.1 - 1.2e-184 614.2 0.2 1.3e-184 614.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGF75847.1 - 0.0002 20.5 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF2274 PF10038.9 EGF75847.1 - 0.059 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) PTS_EIIA_2 PF00359.22 EGF75848.1 - 2.2e-15 56.8 0.3 1.5e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 EGF75848.1 - 5.1e-10 39.9 0.4 4.1e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 PTS system, Lactose/Cellobiose specific IIB subunit PRD PF00874.20 EGF75848.1 - 0.016 15.5 3.3 0.13 12.5 0.0 3.3 4 0 0 4 4 4 0 PRD domain Phage_TAC_12 PF12363.8 EGF75848.1 - 0.092 13.2 0.9 0.6 10.5 0.1 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC EIIC-GAT PF03611.14 EGF75849.1 - 3.2e-149 497.3 44.7 3.2e-149 497.3 44.7 1.5 2 0 0 2 2 2 1 PTS system sugar-specific permease component Transketolase_N PF00456.21 EGF75850.1 - 1.7e-147 490.7 0.0 2e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 EGF75850.1 - 8e-08 31.8 0.0 0.0026 17.0 0.0 2.5 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EGF75850.1 - 4.2e-06 25.9 0.0 6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGF75850.1 - 0.00026 20.8 0.1 0.01 15.6 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TAXi_C PF14541.6 EGF75851.1 - 0.065 13.0 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 EGF75851.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Gly_kinase PF02595.15 EGF75852.1 - 8.5e-122 406.7 5.9 1.1e-121 406.4 5.9 1.0 1 0 0 1 1 1 1 Glycerate kinase family AP_endonuc_2 PF01261.24 EGF75853.1 - 1.9e-16 60.1 0.3 3e-16 59.5 0.3 1.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel 2-Hacid_dh_C PF02826.19 EGF75854.1 - 1.2e-47 161.5 0.0 1.5e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGF75854.1 - 0.0067 16.1 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain UDPG_MGDP_dh_C PF03720.15 EGF75854.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AP_endonuc_2 PF01261.24 EGF75855.1 - 2.1e-14 53.4 0.1 7e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel UxuA PF03786.13 EGF75855.1 - 0.0011 17.9 0.0 0.0014 17.5 0.0 1.0 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) ATPase_2 PF01637.18 EGF75856.1 - 4.3e-07 30.1 0.1 6.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGF75856.1 - 0.0045 17.3 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGF75856.1 - 0.041 13.9 0.1 0.18 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGF75856.1 - 0.045 14.3 0.0 0.1 13.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter W2 PF02020.18 EGF75856.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon AFG1_ATPase PF03969.16 EGF75856.1 - 0.072 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase RNA_helicase PF00910.22 EGF75856.1 - 0.078 13.4 0.1 0.42 11.0 0.0 2.4 2 1 0 2 2 2 0 RNA helicase G10 PF01125.17 EGF75857.1 - 1e-56 190.8 2.2 1.1e-56 190.6 2.2 1.0 1 0 0 1 1 1 1 G10 protein DUF4201 PF13870.6 EGF75858.1 - 9.8e-30 103.6 14.7 9.8e-30 103.6 14.7 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) GMC_oxred_C PF05199.13 EGF75860.1 - 1.2e-17 64.7 0.9 5.1e-17 62.7 0.9 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGF75860.1 - 1.3e-09 37.9 0.0 9.5e-09 35.0 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGF75860.1 - 0.022 13.9 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EGF75860.1 - 0.15 12.1 0.1 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding YojJ PF10372.9 EGF75861.1 - 4e-27 94.1 0.1 6.2e-27 93.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus DisA_N PF02457.16 EGF75861.1 - 3.3e-08 33.1 0.0 5.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding Herpes_UL36 PF03586.13 EGF75861.1 - 0.097 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein HTH_1 PF00126.27 EGF75862.1 - 5.3e-18 64.7 0.0 1.2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Mga PF05043.13 EGF75862.1 - 0.01 16.4 0.4 0.11 13.1 0.1 2.4 2 1 0 2 2 2 0 Mga helix-turn-helix domain DUF1456 PF07308.13 EGF75863.1 - 4.7e-46 155.0 1.7 4e-28 97.5 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) B5 PF03484.15 EGF75863.1 - 0.069 13.5 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetase B5 domain PTS_EIIA_1 PF00358.20 EGF75865.1 - 1.1e-49 167.5 1.9 1.8e-49 166.7 1.9 1.4 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS_EIIC PF02378.18 EGF75865.1 - 3.4e-22 78.9 38.2 3.4e-22 78.9 38.2 1.5 1 1 0 1 1 1 1 Phosphotransferase system, EIIC Biotin_lipoyl_2 PF13533.6 EGF75865.1 - 0.0042 16.9 3.4 0.042 13.7 0.4 3.1 3 0 0 3 3 3 1 Biotin-lipoyl like ATPase PF06745.13 EGF75866.1 - 0.1 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 KaiC FMN_red PF03358.15 EGF75867.1 - 5.1e-16 58.8 0.0 6.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase YjcZ_2 PF09680.10 EGF75867.1 - 6.8e-11 41.6 10.2 6.8e-11 41.6 10.2 2.4 2 0 0 2 2 2 1 Family of unknown function Flavodoxin_2 PF02525.17 EGF75867.1 - 5.8e-05 22.9 0.0 9.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Phage_Gp23 PF10669.9 EGF75867.1 - 0.057 13.7 0.7 0.3 11.4 0.5 2.0 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) AAA PF00004.29 EGF75868.1 - 2.1e-23 83.2 0.0 6.6e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGF75868.1 - 1.3e-06 28.5 0.1 1.4e-05 25.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF75868.1 - 4.3e-05 23.9 0.1 0.0048 17.3 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGF75868.1 - 0.00097 19.5 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EGF75868.1 - 0.0046 17.2 0.3 0.062 13.6 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EGF75868.1 - 0.0067 16.2 0.5 0.079 12.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain DNA_pol3_delta2 PF13177.6 EGF75868.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 EGF75868.1 - 0.0097 15.7 0.1 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Hexokinase_1 PF00349.21 EGF75868.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Mg_chelatase PF01078.21 EGF75868.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGF75868.1 - 0.018 14.9 0.1 0.061 13.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_17 PF13207.6 EGF75868.1 - 0.027 14.9 0.7 9.4 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGF75868.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGF75868.1 - 0.032 13.8 0.3 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGF75868.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EGF75868.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGF75868.1 - 0.064 12.4 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EGF75868.1 - 0.068 12.3 0.2 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EGF75868.1 - 0.072 12.4 1.0 0.29 10.5 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_29 PF13555.6 EGF75868.1 - 0.077 12.8 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_UL92 PF03048.14 EGF75868.1 - 0.081 12.7 0.7 13 5.5 0.0 2.3 2 0 0 2 2 2 0 UL92 family Sigma54_activ_2 PF14532.6 EGF75868.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 EGF75868.1 - 0.11 12.6 0.3 0.75 9.9 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Bac_DnaA PF00308.18 EGF75868.1 - 0.14 12.0 1.7 1.3 8.8 0.0 2.9 1 1 1 2 2 2 0 Bacterial dnaA protein RNase_J_C PF17770.1 EGF75868.1 - 0.27 12.3 2.2 10 7.3 0.0 3.5 4 0 0 4 4 3 0 Ribonuclease J C-terminal domain ATPase_2 PF01637.18 EGF75868.1 - 1.6 8.6 7.4 2.2 8.1 0.1 2.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Aminotran_1_2 PF00155.21 EGF75869.1 - 3.8e-64 217.1 0.0 4.3e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGF75869.1 - 4.1e-10 39.2 0.0 1.1e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGF75869.1 - 5.9e-07 29.1 0.0 8.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 EGF75869.1 - 0.0035 16.3 0.0 0.058 12.3 0.0 2.1 1 1 1 2 2 2 1 Allinase Cys_Met_Meta_PP PF01053.20 EGF75869.1 - 0.004 15.7 0.0 0.0075 14.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pur_ac_phosph_N PF16656.5 EGF75870.1 - 1.5e-16 60.7 1.5 5.5e-16 58.9 0.6 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGF75870.1 - 4.5e-15 56.7 0.6 9.1e-15 55.7 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD_N PF16655.5 EGF75870.1 - 0.0004 20.8 0.1 0.00089 19.7 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain LysM PF01476.20 EGF75871.1 - 5.1e-44 148.1 1.9 5.9e-14 51.8 0.1 3.5 3 0 0 3 3 3 3 LysM domain Glyco_hydro_18 PF00704.28 EGF75871.1 - 3e-23 83.0 0.1 4.1e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GFO_IDH_MocA PF01408.22 EGF75872.1 - 1.3e-33 116.4 0.7 2.1e-33 115.7 0.7 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGF75872.1 - 7.3e-09 36.3 0.3 1.3e-08 35.4 0.3 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 EGF75872.1 - 7.3e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_trans_4_2 PF13477.6 EGF75872.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Semialdhyde_dh PF01118.24 EGF75872.1 - 0.0048 17.3 0.2 0.011 16.1 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGF75872.1 - 0.006 16.8 0.4 0.012 15.9 0.4 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGF75872.1 - 0.034 14.6 0.3 0.066 13.7 0.3 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EGF75872.1 - 0.054 14.1 0.4 0.14 12.7 0.2 1.8 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HMGL-like PF00682.19 EGF75872.1 - 0.068 12.7 0.5 0.13 11.7 0.5 1.4 1 1 0 1 1 1 0 HMGL-like HAD_2 PF13419.6 EGF75873.1 - 3.5e-12 46.8 2.0 2.2e-11 44.1 0.3 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGF75873.1 - 0.0045 17.0 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGF75873.1 - 0.0065 16.8 0.0 0.01 16.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lar_N PF09861.9 EGF75874.1 - 1.7e-08 33.9 0.3 3.2e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Lactate racemase N-terminal domain DUF2391 PF09622.10 EGF75874.1 - 0.087 12.1 0.1 0.63 9.3 0.1 2.0 1 1 0 1 1 1 0 Putative integral membrane protein (DUF2391) GntR PF00392.21 EGF75875.1 - 7.7e-13 47.9 0.1 1.2e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Phage_rep_O PF04492.13 EGF75875.1 - 0.024 15.2 0.5 0.2 12.3 0.0 2.3 2 1 1 3 3 3 0 Bacteriophage replication protein O HTH_57 PF18679.1 EGF75875.1 - 0.047 14.0 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 ThcOx helix turn helix domain HTH_24 PF13412.6 EGF75875.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGF75875.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 EGF75875.1 - 0.11 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ADH_N PF08240.12 EGF75876.1 - 3.6e-34 116.9 0.6 5.6e-34 116.3 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGF75876.1 - 2.9e-30 104.9 0.2 4.4e-30 104.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGF75876.1 - 1e-08 34.9 0.3 1.6e-08 34.3 0.3 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGF75876.1 - 1e-06 29.8 0.1 1.8e-06 29.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EPSP_synthase PF00275.20 EGF75876.1 - 0.056 12.1 0.9 0.097 11.3 0.1 1.7 2 0 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Methyltransf_25 PF13649.6 EGF75876.1 - 0.099 13.4 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain LysR_substrate PF03466.20 EGF75877.1 - 5.3e-32 110.9 0.0 5.9e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain PBP_like_2 PF12849.7 EGF75877.1 - 0.0038 16.9 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 2 PBP superfamily domain IBN_N PF03810.19 EGF75877.1 - 0.022 14.7 0.7 0.72 9.8 0.0 2.6 3 0 0 3 3 3 0 Importin-beta N-terminal domain DivIC PF04977.15 EGF75878.1 - 0.00074 19.2 0.6 0.00074 19.2 0.6 2.7 1 1 1 2 2 1 1 Septum formation initiator V_ATPase_I PF01496.19 EGF75878.1 - 0.0014 16.7 7.3 0.0017 16.4 7.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Slp PF03843.13 EGF75878.1 - 0.0048 16.3 0.4 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Outer membrane lipoprotein Slp family UPF0242 PF06785.11 EGF75878.1 - 0.014 15.5 15.5 0.02 15.0 15.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ABC2_membrane_3 PF12698.7 EGF75878.1 - 0.023 13.8 1.1 0.034 13.2 1.1 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4446 PF14584.6 EGF75878.1 - 0.027 14.5 2.5 0.027 14.5 2.5 2.2 1 1 1 2 2 1 0 Protein of unknown function (DUF4446) DDHD PF02862.17 EGF75878.1 - 0.032 14.4 1.6 0.036 14.2 1.6 1.2 1 0 0 1 1 1 0 DDHD domain Baculo_11_kDa PF06143.11 EGF75878.1 - 0.034 13.7 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family SID-1_RNA_chan PF13965.6 EGF75878.1 - 0.035 12.5 3.0 0.045 12.2 3.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM209 PF15206.6 EGF75878.1 - 0.058 13.2 0.5 0.058 13.2 0.5 2.0 2 0 0 2 2 2 0 FAM209 family Synaptobrevin PF00957.21 EGF75878.1 - 0.059 13.2 0.8 0.059 13.2 0.8 2.4 2 0 0 2 2 2 0 Synaptobrevin Fez1 PF06818.15 EGF75878.1 - 0.073 13.5 19.7 0.099 13.1 19.7 1.1 1 0 0 1 1 1 0 Fez1 FapA PF03961.13 EGF75878.1 - 0.078 11.6 13.5 0.11 11.1 13.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Neur_chan_memb PF02932.16 EGF75878.1 - 0.087 12.9 1.7 0.12 12.4 1.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4969 PF16339.5 EGF75878.1 - 0.099 13.0 2.1 0.19 12.1 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) SAPS PF04499.15 EGF75878.1 - 0.12 11.1 10.4 0.15 10.8 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2152 PF10222.9 EGF75878.1 - 0.12 10.6 0.2 0.2 10.0 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) AAA_13 PF13166.6 EGF75878.1 - 0.14 10.8 15.3 0.18 10.4 15.3 1.1 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 EGF75878.1 - 0.14 12.4 7.1 0.18 12.1 7.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 EGF75878.1 - 0.29 10.3 2.3 0.45 9.7 2.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 EGF75878.1 - 0.35 8.9 8.3 0.43 8.6 8.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ALMT PF11744.8 EGF75878.1 - 0.42 9.4 6.6 0.51 9.1 6.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter RR_TM4-6 PF06459.12 EGF75878.1 - 0.46 10.3 19.7 0.64 9.8 19.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GNT-I PF03071.15 EGF75878.1 - 0.53 9.0 5.3 0.41 9.4 4.1 1.3 1 1 0 1 1 1 0 GNT-I family CCDC53 PF10152.9 EGF75878.1 - 0.56 10.6 11.1 0.75 10.2 11.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TP53IP5 PF15331.6 EGF75878.1 - 0.67 10.1 8.2 0.9 9.6 8.2 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Conotoxin PF02950.17 EGF75878.1 - 0.98 10.5 13.2 2.9e+02 2.6 13.2 2.6 1 1 0 1 1 1 0 Conotoxin DUF2254 PF10011.9 EGF75878.1 - 0.98 8.2 7.2 10 4.8 7.3 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) tRNA_anti-like PF12869.7 EGF75878.1 - 1.3 8.6 13.1 36 3.9 13.1 2.8 1 1 0 1 1 1 0 tRNA_anti-like DUF913 PF06025.12 EGF75878.1 - 1.9 7.4 5.3 2.5 7.0 5.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Golgin_A5 PF09787.9 EGF75878.1 - 4.8 6.6 18.6 6.7 6.1 18.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 SIT PF15330.6 EGF75878.1 - 9.8 6.7 7.5 73 3.8 7.7 2.0 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Pectate_lyase_3 PF12708.7 EGF75880.1 - 0.0069 16.3 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 Pectate lyase superfamily protein Cdh1_DBD_1 PF18196.1 EGF75880.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 FAD_binding_2 PF00890.24 EGF75881.1 - 2.3e-46 158.7 0.0 9.8e-46 156.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGF75881.1 - 3.9e-08 33.1 3.6 3.4e-06 26.7 0.3 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGF75881.1 - 1.5e-07 30.5 1.5 0.00014 20.8 0.0 2.9 2 1 0 3 3 3 2 HI0933-like protein DAO PF01266.24 EGF75881.1 - 6.5e-06 26.0 0.6 0.00015 21.5 0.4 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGF75881.1 - 7.3e-06 26.5 1.8 0.17 12.5 0.2 3.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGF75881.1 - 2.8e-05 23.5 1.1 0.0016 17.7 0.8 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGF75881.1 - 0.00065 19.1 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EGF75881.1 - 0.0014 17.9 0.1 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EGF75881.1 - 0.0018 17.7 0.1 0.038 13.3 0.0 2.2 1 1 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 EGF75881.1 - 0.0028 16.8 7.0 0.2 10.7 0.0 3.2 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGF75881.1 - 0.027 14.7 0.4 0.099 12.9 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain WDCP PF15390.6 EGF75882.1 - 0.0031 16.0 8.4 0.0042 15.5 8.4 1.2 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family YjcZ PF13990.6 EGF75882.1 - 0.081 12.3 0.6 0.15 11.4 0.6 1.4 1 0 0 1 1 1 0 YjcZ-like protein Uds1 PF15456.6 EGF75882.1 - 3.6 7.8 6.2 12 6.0 0.3 2.9 1 1 0 2 2 2 0 Up-regulated During Septation Aminotran_5 PF00266.19 EGF75883.1 - 2.8e-33 115.4 0.0 5.2e-33 114.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M29 PF02073.15 EGF75883.1 - 8.6e-08 31.4 0.0 1.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Cys_Met_Meta_PP PF01053.20 EGF75883.1 - 0.00037 19.2 0.1 0.00053 18.6 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SDF PF00375.18 EGF75884.1 - 1.1e-68 232.0 43.4 3.3e-59 200.9 31.6 2.2 1 1 1 2 2 2 2 Sodium:dicarboxylate symporter family Peptidase_C39_2 PF13529.6 EGF75885.1 - 1.3e-29 103.7 0.2 3.3e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 EGF75885.1 - 5.7e-05 22.9 0.1 0.23 11.2 0.0 2.9 3 0 0 3 3 3 2 Peptidase C39 family SpaA PF17802.1 EGF75885.1 - 9.6e-05 22.6 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Prealbumin-like fold domain Peptidase_C10 PF01640.17 EGF75885.1 - 0.012 16.0 0.1 1.2 9.4 0.0 2.4 1 1 1 2 2 2 0 Peptidase C10 family Peptidase_C70 PF12385.8 EGF75885.1 - 0.015 15.3 0.0 1.4 8.9 0.0 3.0 1 1 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Lactamase_B PF00753.27 EGF75887.1 - 5.8e-15 55.8 0.1 1.4e-14 54.6 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HHH_3 PF12836.7 EGF75887.1 - 3.5e-10 40.0 0.0 6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Lactamase_B_2 PF12706.7 EGF75887.1 - 2.4e-07 30.5 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EGF75887.1 - 8.4e-05 22.1 0.1 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain HHH PF00633.23 EGF75887.1 - 0.0027 17.5 0.0 0.78 9.7 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif PsbU PF06514.11 EGF75887.1 - 0.028 14.4 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_5 PF14520.6 EGF75887.1 - 0.04 14.5 0.3 2.5 8.7 0.1 2.5 1 1 2 3 3 3 0 Helix-hairpin-helix domain DUF1869 PF08956.10 EGF75887.1 - 0.059 13.3 0.3 1 9.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) CPSF100_C PF13299.6 EGF75887.1 - 1.7 8.8 4.8 5.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal tRNA_edit PF04073.15 EGF75888.1 - 3.1e-26 91.9 0.0 4.5e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain YdjM PF04307.14 EGF75888.1 - 3.4e-13 49.3 1.6 6.3e-13 48.4 1.6 1.5 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase HMGL-like PF00682.19 EGF75889.1 - 4.8e-50 170.6 0.0 5.5e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Peptidase_S28 PF05577.12 EGF75890.1 - 0.23 10.2 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 SNF2_N PF00176.23 EGF75891.1 - 7.2e-15 54.5 0.1 2.2e-13 49.7 0.1 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF75891.1 - 9.6e-14 51.7 0.1 3.7e-13 49.8 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF75891.1 - 9.7e-08 32.2 0.8 7.8e-07 29.2 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1998 PF09369.10 EGF75891.1 - 1.6e-07 32.0 0.1 6.7e-07 30.0 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) DEAD PF00270.29 EGF75891.1 - 2.5e-05 24.1 1.0 0.00036 20.3 0.0 3.0 3 1 0 3 3 3 1 DEAD/DEAH box helicase UPF0149 PF03695.13 EGF75891.1 - 0.034 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) TarH PF02203.15 EGF75891.1 - 0.053 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue Ground-like PF04155.18 EGF75891.1 - 0.17 12.6 2.4 0.3 11.8 0.1 2.8 3 0 0 3 3 3 0 Ground-like domain CbiA PF01656.23 EGF75891.1 - 1.2 9.3 2.9 24 5.0 0.1 3.6 4 1 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4404 PF14357.6 EGF75891.1 - 1.4 9.6 4.2 1 10.1 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) ACP_syn_III_C PF08541.10 EGF75893.1 - 3.4e-21 75.2 0.0 3.2e-19 68.9 0.0 2.9 3 1 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGF75893.1 - 4.3e-16 58.5 0.1 7.5e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 EGF75893.1 - 0.00085 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Thiolase_C PF02803.18 EGF75893.1 - 0.071 12.8 0.1 2 8.1 0.0 2.3 2 1 0 2 2 2 0 Thiolase, C-terminal domain DUF2184 PF09950.9 EGF75893.1 - 0.12 11.8 0.1 0.39 10.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) EamA PF00892.20 EGF75894.1 - 1.9e-21 76.6 18.0 6.4e-12 45.8 5.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family MASE4 PF17158.4 EGF75894.1 - 0.01 15.1 7.9 0.063 12.5 3.0 2.4 1 1 1 2 2 2 0 Membrane-associated sensor, integral membrane domain Mg_trans_NIPA PF05653.14 EGF75894.1 - 0.071 12.2 9.1 0.1 11.7 6.1 2.3 1 1 1 2 2 2 0 Magnesium transporter NIPA DUF5518 PF17647.1 EGF75894.1 - 0.2 11.8 11.8 2.1 8.5 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) DUF5090 PF17009.5 EGF75894.1 - 0.22 11.5 7.6 0.31 11.0 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Wzy_C PF04932.15 EGF75894.1 - 0.22 11.1 13.0 1.8e+02 1.7 13.0 2.6 1 1 0 1 1 1 0 O-Antigen ligase DUF4203 PF13886.6 EGF75894.1 - 0.49 10.0 15.7 0.83 9.3 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) LRR19-TM PF15176.6 EGF75894.1 - 0.92 9.5 3.2 0.65 10.0 0.2 2.3 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain TctB PF07331.11 EGF75894.1 - 2.6 8.3 15.9 5.4 7.3 15.9 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3487 PF11990.8 EGF75894.1 - 6.6 6.6 13.0 2.9 7.8 0.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3487) Aldedh PF00171.22 EGF75895.1 - 1.1e-166 555.0 0.1 1.2e-166 554.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 EGF75895.1 - 0.093 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated LuxC PF05893.14 EGF75895.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF779 PF05610.11 EGF75896.1 - 5.1e-41 138.8 0.1 6e-41 138.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF779) Asp PF00026.23 EGF75897.1 - 8.9e-13 48.3 0.0 4.1e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF75897.1 - 0.033 14.0 0.0 0.085 12.6 0.0 1.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal UPF0449 PF15136.6 EGF75898.1 - 0.012 16.1 0.5 0.018 15.5 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 CC2-LZ PF16516.5 EGF75898.1 - 0.017 15.5 1.8 0.027 14.8 1.8 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4533 PF15047.6 EGF75899.1 - 0.023 14.3 0.7 0.036 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) FliD_C PF07195.12 EGF75899.1 - 0.03 13.7 0.5 0.049 13.1 0.5 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlxA PF14282.6 EGF75899.1 - 0.041 13.9 3.0 0.077 13.0 3.0 1.4 1 0 0 1 1 1 0 FlxA-like protein Cnl2_NKP2 PF09447.10 EGF75899.1 - 0.065 13.4 0.4 0.21 11.7 0.2 1.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Prefoldin PF02996.17 EGF75899.1 - 0.098 12.6 2.3 1.4 8.8 1.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit B277 PF17623.2 EGF75899.1 - 0.12 11.5 0.7 0.18 10.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function Glycoprot_B_PH2 PF17417.2 EGF75899.1 - 0.12 12.7 2.2 7.6 7.0 0.2 2.1 1 1 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain DUF4106 PF13388.6 EGF75899.1 - 0.29 10.3 3.1 0.39 9.9 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) LRR_10 PF18805.1 EGF75902.1 - 0.27 10.9 2.2 0.6 9.8 2.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat CopD PF05425.13 EGF75903.1 - 1.6e-07 31.7 1.2 1.6e-07 31.7 1.2 2.4 2 1 1 3 3 3 1 Copper resistance protein D BCCT PF02028.17 EGF75904.1 - 1.5e-188 627.2 45.5 1.5e-188 627.2 45.5 1.4 2 0 0 2 2 2 1 BCCT, betaine/carnitine/choline family transporter XPC-binding PF09280.11 EGF75907.1 - 0.13 12.1 0.2 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 XPC-binding domain EamA PF00892.20 EGF75910.1 - 1.5e-13 51.1 50.9 3.8e-09 36.8 21.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLAC1 PF03595.17 EGF75910.1 - 0.032 13.5 38.1 0.047 13.0 37.4 1.7 1 1 0 1 1 1 0 Voltage-dependent anion channel DMT_6 PF04342.12 EGF75910.1 - 1.3 9.3 11.3 0.14 12.4 0.6 3.4 2 1 1 3 3 3 0 Putative member of DMT superfamily (DUF486) DPM3 PF08285.11 EGF75910.1 - 2.1 8.6 5.8 8.6 6.6 1.2 2.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) GerE PF00196.19 EGF75911.1 - 6.3e-16 57.7 0.6 9.3e-16 57.1 0.6 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EGF75911.1 - 8.4e-07 28.6 0.1 1.4e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EGF75911.1 - 4.1e-06 26.2 0.0 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 EGF75911.1 - 0.0021 17.8 0.2 0.0036 17.1 0.2 1.4 1 0 0 1 1 1 1 HTH DNA binding domain FaeA PF04703.12 EGF75911.1 - 0.0073 16.7 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 FaeA-like protein DUF134 PF02001.16 EGF75911.1 - 0.016 15.8 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_Mga PF08280.11 EGF75911.1 - 0.052 13.6 0.6 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_ECF PF07638.11 EGF75911.1 - 0.065 13.1 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor GAF_2 PF13185.6 EGF75911.1 - 0.067 13.5 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 GAF domain HTH_29 PF13551.6 EGF75911.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF4015 PF13200.6 EGF75912.1 - 3.5e-92 308.8 3.1 3.8e-92 308.7 3.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain DIT1_PvcA PF05141.12 EGF75912.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF5342 PF17277.2 EGF75913.1 - 2.1e-05 24.8 3.6 0.068 13.5 0.2 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5342) Lsr2 PF11774.8 EGF75913.1 - 0.077 13.1 0.3 3.2 7.9 0.0 2.3 2 1 0 2 2 2 0 Lsr2 cobW PF02492.19 EGF75914.1 - 6.3e-40 136.6 0.0 7.5e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGF75914.1 - 0.0013 17.7 0.1 0.1 11.6 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EGF75914.1 - 0.011 15.3 0.3 0.13 11.8 0.1 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.12 EGF75914.1 - 0.022 14.1 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 EGF75914.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 EGF75914.1 - 0.063 12.5 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 EGF75914.1 - 0.069 13.7 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MobB PF03205.14 EGF75914.1 - 0.13 12.2 0.1 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EGF75914.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 EGF75914.1 - 0.14 11.1 0.0 0.53 9.1 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain AAA_23 PF13476.6 EGF75914.1 - 0.14 12.7 0.1 0.22 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain UreF PF01730.16 EGF75915.1 - 6.9e-32 110.8 0.0 8.2e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 UreF Amidohydro_1 PF01979.20 EGF75916.1 - 8.1e-23 81.3 0.1 9.8e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGF75916.1 - 1.9e-07 31.0 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Transp_cyt_pur PF02133.15 EGF75917.1 - 1.2e-15 57.2 34.6 1.7e-12 46.9 33.4 2.3 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L11_N PF03946.14 EGF75917.1 - 0.016 15.0 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain DUF917 PF06032.12 EGF75918.1 - 3.2e-135 450.5 0.3 3.6e-135 450.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) DUF2666 PF10869.8 EGF75918.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Hydantoinase_A PF01968.18 EGF75919.1 - 1.2e-37 129.8 3.2 6e-35 120.9 1.3 2.4 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGF75919.1 - 2e-24 86.3 1.2 2e-21 76.5 0.2 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.11 EGF75919.1 - 0.002 17.4 0.1 1.6 7.9 0.0 2.5 2 0 0 2 2 2 2 StbA protein MutL PF13941.6 EGF75919.1 - 0.01 14.4 0.1 0.027 13.1 0.1 1.6 2 0 0 2 2 2 0 MutL protein GA-like PF17573.2 EGF75919.1 - 0.39 10.7 3.1 1.8 8.6 0.5 2.4 2 0 0 2 2 2 0 GA-like domain MMR_HSR1 PF01926.23 EGF75920.1 - 1.2e-06 28.5 0.1 3.6e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGF75920.1 - 3.8e-06 27.1 2.7 3.1e-05 24.1 2.7 2.2 1 1 0 1 1 1 1 Dynamin family TPR_8 PF13181.6 EGF75920.1 - 3.1e-05 23.9 0.9 0.013 15.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF75920.1 - 4e-05 23.4 0.8 0.57 10.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF75920.1 - 0.00018 21.1 0.1 0.0069 16.0 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 EGF75920.1 - 0.00026 20.7 1.7 0.12 12.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.6 EGF75920.1 - 0.00064 19.2 1.9 0.49 9.8 0.1 2.5 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 EGF75920.1 - 0.0052 17.5 0.0 0.38 11.7 0.0 3.6 4 1 0 4 4 3 1 Tetratricopeptide repeat Septin PF00735.18 EGF75920.1 - 0.023 14.0 0.1 0.048 12.9 0.1 1.6 1 0 0 1 1 1 0 Septin Roc PF08477.13 EGF75920.1 - 0.078 13.2 0.5 0.54 10.5 0.1 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGF75920.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_luciferase PF00296.20 EGF75921.1 - 5.2e-63 213.4 0.0 6.6e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SBP_bac_5 PF00496.22 EGF75922.1 - 1.6e-10 40.5 0.3 2.1e-10 40.1 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BssC_TutF PF08201.11 EGF75922.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 BssC/TutF protein Golgin_A5 PF09787.9 EGF75923.1 - 0.0097 15.4 2.0 0.012 15.1 2.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 FAD_oxidored PF12831.7 EGF75925.1 - 9.9e-108 361.3 0.0 1.1e-107 361.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGF75925.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGF75925.1 - 3.9e-06 26.2 7.5 1.7e-05 24.1 3.9 2.1 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGF75925.1 - 7e-06 26.2 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGF75925.1 - 2e-05 24.0 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGF75925.1 - 0.00017 21.0 0.1 0.092 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGF75925.1 - 0.00078 18.3 4.9 0.0017 17.2 1.3 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EGF75925.1 - 0.00078 18.6 2.1 0.00078 18.6 2.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 EGF75925.1 - 0.0013 18.4 3.7 0.075 12.6 4.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGF75925.1 - 0.0075 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EGF75925.1 - 0.01 14.9 0.2 0.021 13.9 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EGF75925.1 - 0.061 13.9 3.4 0.99 10.0 0.7 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EGF75925.1 - 0.22 10.0 0.7 0.52 8.8 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GFO_IDH_MocA PF01408.22 EGF75926.1 - 3.5e-25 89.2 0.5 8e-25 88.0 0.5 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGF75926.1 - 5.4e-08 32.8 0.1 1.6e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4436 PF14494.6 EGF75926.1 - 0.017 14.4 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Transposase_22 PF02994.14 EGF75926.1 - 0.037 14.2 0.1 0.079 13.1 0.1 1.6 1 0 0 1 1 1 0 L1 transposable element RBD-like domain Semialdhyde_dh PF01118.24 EGF75926.1 - 0.092 13.2 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SBP_bac_5 PF00496.22 EGF75927.1 - 7.3e-71 239.1 4.7 1e-70 238.7 4.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle gp37_C PF12604.8 EGF75927.1 - 0.069 12.8 0.8 0.15 11.8 0.8 1.5 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal Lipase_GDSL_3 PF14606.6 EGF75928.1 - 1.2e-44 152.6 0.0 1.7e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GxDLY PF14607.6 EGF75928.1 - 8.5e-40 135.9 0.0 1.2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 N-terminus of Esterase_SGNH_hydro-type Lipase_GDSL_2 PF13472.6 EGF75928.1 - 9.8e-10 39.1 0.0 2.9e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGF75928.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Endonuclease_1 PF04231.13 EGF75929.1 - 2.8e-47 161.3 0.4 4.9e-47 160.6 0.4 1.4 1 0 0 1 1 1 1 Endonuclease I Big_9 PF17963.1 EGF75929.1 - 0.016 16.0 6.9 0.032 15.0 4.9 2.5 2 0 0 2 2 2 0 Bacterial Ig domain Cadherin_4 PF17803.1 EGF75929.1 - 1.2 9.8 7.4 0.56 10.9 3.5 2.6 2 1 0 2 2 2 0 Bacterial cadherin-like domain Epimerase PF01370.21 EGF75930.1 - 1.7e-57 194.6 0.1 1.9e-57 194.5 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF75930.1 - 3e-48 164.9 0.4 3.5e-48 164.7 0.4 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGF75930.1 - 3.9e-23 81.8 0.5 4.9e-23 81.5 0.5 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGF75930.1 - 2.1e-20 73.0 1.2 1.4e-19 70.3 1.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGF75930.1 - 2e-18 66.5 0.1 2.4e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGF75930.1 - 4.1e-15 55.7 0.1 4.4e-10 39.2 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGF75930.1 - 2.2e-09 37.5 0.0 3.4e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGF75930.1 - 1.5e-05 24.7 0.7 2.7e-05 23.9 0.7 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGF75930.1 - 0.0093 15.4 0.1 0.028 13.9 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF75930.1 - 0.047 13.6 0.0 0.49 10.3 0.0 2.1 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 EGF75930.1 - 0.077 13.3 0.1 0.11 12.7 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EGF75930.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.20 EGF75931.1 - 1.7e-15 57.0 0.0 2.5e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF75931.1 - 8.8e-15 55.3 0.0 1.2e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGF75931.1 - 0.00012 22.2 0.0 0.058 13.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EGF75931.1 - 0.00049 20.4 0.0 2.7 8.5 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGF75932.1 - 4.4e-18 65.5 0.0 2.7e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3880 PF12996.7 EGF75932.1 - 7.2e-09 35.6 1.9 2e-07 31.0 0.1 3.3 3 0 0 3 3 3 1 DUF based on E. rectale Gene description (DUF3880) Glycos_transf_1 PF00534.20 EGF75932.1 - 0.00012 21.7 0.0 0.00069 19.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF75932.1 - 0.00014 22.3 0.0 0.0004 20.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF4091 PF13320.6 EGF75932.1 - 0.051 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) IFRD PF05004.13 EGF75932.1 - 0.09 11.9 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) ABC_tran PF00005.27 EGF75933.1 - 4.2e-19 69.4 0.4 1.7e-18 67.4 0.4 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF75933.1 - 1.2e-05 25.2 5.0 0.057 13.2 2.0 3.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Bac_rhamnosid6H PF17389.2 EGF75933.1 - 0.026 13.8 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MMR_HSR1 PF01926.23 EGF75933.1 - 0.035 14.2 1.0 0.13 12.4 0.6 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGF75933.1 - 0.076 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGF75933.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGF75933.1 - 0.34 10.3 1.9 0.67 9.3 0.8 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGF75933.1 - 0.41 10.6 2.8 0.23 11.4 0.2 1.9 3 0 0 3 3 3 0 RsgA GTPase p450 PF00067.22 EGF75934.1 - 6.2e-42 143.9 0.2 7.7e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 DeoRC PF00455.22 EGF75936.1 - 9.3e-43 145.9 0.7 1.4e-42 145.3 0.7 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EGF75936.1 - 1.6e-10 40.5 0.0 3.7e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EGF75936.1 - 0.0014 18.5 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 HTH domain Put_DNA-bind_N PF06971.13 EGF75936.1 - 0.05 13.6 0.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus MatE PF01554.18 EGF75937.1 - 1.1e-35 122.7 46.0 1.2e-19 70.5 18.6 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGF75937.1 - 0.00056 20.0 23.8 0.00056 20.0 23.8 4.5 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Metallophos PF00149.28 EGF75938.1 - 4.3e-17 63.3 1.5 5.6e-17 62.9 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amidohydro_2 PF04909.14 EGF75938.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase ComA PF02679.15 EGF75938.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) RNAse_A_bac PF18431.1 EGF75938.1 - 0.12 13.4 0.0 0.19 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain SBP_bac_1 PF01547.25 EGF75939.1 - 1.4e-05 25.2 0.6 0.00035 20.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein CHASE8 PF17152.4 EGF75939.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain Cupin_2 PF07883.11 EGF75940.1 - 1.6e-12 46.9 0.0 2.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EGF75940.1 - 0.00048 20.1 0.0 0.00059 19.8 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EGF75940.1 - 0.0074 16.2 0.0 0.056 13.4 0.0 2.2 1 1 2 3 3 3 1 AraC-like ligand binding domain TetR_N PF00440.23 EGF75941.1 - 1.5e-06 27.9 0.2 5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_8 PF14278.6 EGF75941.1 - 3.3e-05 23.9 0.7 8.8e-05 22.6 0.1 1.9 1 1 1 2 2 2 1 Transcriptional regulator C-terminal region Glutaminase PF04960.15 EGF75941.1 - 0.032 13.4 0.2 0.08 12.1 0.2 1.5 1 1 0 1 1 1 0 Glutaminase ydhR PF08803.11 EGF75942.1 - 1.9e-41 139.9 0.1 2.1e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR FMN_red PF03358.15 EGF75943.1 - 6.1e-32 110.5 0.0 7.8e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGF75943.1 - 4.5e-06 26.5 0.0 5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold ACR_tran PF00873.19 EGF75944.1 - 1.1e-204 682.2 38.1 1.2e-204 682.0 38.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EGF75944.1 - 1.2e-10 40.9 22.5 6e-07 28.7 5.0 2.6 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 EGF75944.1 - 6.3e-10 38.8 31.1 6.6e-05 22.4 10.1 2.6 2 0 0 2 2 2 2 Protein export membrane protein SRP54_N PF02881.19 EGF75944.1 - 1.9 8.7 5.4 6.2 7.1 0.1 3.6 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain Lipase_3 PF01764.25 EGF75946.1 - 9.6e-27 93.6 0.0 1.8e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGF75946.1 - 5.3e-06 26.1 0.0 0.0051 16.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) PDH_E1_M PF17831.1 EGF75946.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Pyruvate dehydrogenase E1 component middle domain Lipase_3 PF01764.25 EGF75947.1 - 1.6e-29 102.6 0.0 2.1e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 EGF75947.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 EGF75947.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 EGF75947.1 - 0.062 12.8 0.1 0.094 12.2 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Aldo_ket_red PF00248.21 EGF75948.1 - 1e-49 169.3 0.0 5.1e-40 137.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family KaiA PF07688.12 EGF75948.1 - 0.089 13.0 0.4 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 KaiA C-terminal domain DUF1798 PF08807.10 EGF75948.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF3642 PF12182.8 EGF75948.1 - 0.2 12.0 1.5 0.62 10.4 0.1 2.6 2 2 2 4 4 4 0 Bacterial lipoprotein OPT PF03169.15 EGF75950.1 - 6.8e-82 276.0 35.3 7.6e-82 275.9 35.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NUDE_C PF04880.13 EGF75951.1 - 1.2 9.6 4.4 2.9 8.4 4.4 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Amidohydro_2 PF04909.14 EGF75952.1 - 6e-28 98.5 0.0 1.3e-27 97.4 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase DnaT PF17948.1 EGF75952.1 - 0.026 14.2 1.2 0.052 13.2 1.2 1.5 1 0 0 1 1 1 0 DnaT DNA-binding domain Thioredoxin_9 PF14595.6 EGF75953.1 - 1.2e-39 135.0 1.0 1.5e-39 134.7 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 EGF75953.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin TIP49 PF06068.13 EGF75953.1 - 0.16 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Aldedh PF00171.22 EGF75954.1 - 2.7e-30 105.3 0.0 3e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3813 PF12758.7 EGF75954.1 - 0.053 13.9 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) PRK PF00485.18 EGF75955.1 - 4.6e-10 39.6 0.1 0.00069 19.4 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGF75955.1 - 2.7e-08 34.4 0.0 3.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGF75955.1 - 4.3e-05 23.3 0.0 0.06 13.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase APS_kinase PF01583.20 EGF75955.1 - 5.7e-05 23.1 0.0 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EGF75955.1 - 0.00036 19.9 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 EGF75955.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EGF75955.1 - 0.0019 18.5 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGF75955.1 - 0.0043 17.1 0.0 0.0066 16.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 EGF75955.1 - 0.006 16.5 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_16 PF13191.6 EGF75955.1 - 0.007 16.8 0.0 0.008 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EGF75955.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGF75955.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 EGF75955.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_24 PF13479.6 EGF75955.1 - 0.024 14.3 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGF75955.1 - 0.029 14.8 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 EGF75955.1 - 0.029 14.0 0.1 4.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase KAP_NTPase PF07693.14 EGF75955.1 - 0.034 13.4 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 EGF75955.1 - 0.063 13.3 0.1 0.15 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EGF75955.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 EGF75955.1 - 0.071 12.3 0.1 0.15 11.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EGF75955.1 - 0.097 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Peptidase_M42 PF05343.14 EGF75957.1 - 2.1e-62 210.8 0.6 2.2e-45 154.9 0.3 2.0 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EGF75957.1 - 1.8e-05 24.6 0.2 0.012 15.4 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Catalase PF00199.19 EGF75958.1 - 3.3e-184 612.4 2.2 4.6e-184 611.9 2.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGF75958.1 - 1.3e-21 76.6 0.1 3.2e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EGF75958.1 - 2.8e-18 66.0 0.0 2.9e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EGF75958.1 - 2.4e-07 30.7 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 EGF75959.1 - 6.3e-37 127.3 55.0 6.3e-37 127.3 55.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIISA_toxin PF14171.6 EGF75959.1 - 0.065 12.9 1.4 0.15 11.7 1.4 1.5 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system UvdE PF03851.14 EGF75960.1 - 4.4e-61 206.6 2.2 4.8e-61 206.4 2.2 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE UvdE PF03851.14 EGF75961.1 - 6.6e-90 301.1 4.8 7.8e-90 300.8 4.8 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 EGF75961.1 - 0.0029 17.1 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TaqI_C PF12950.7 EGF75961.1 - 0.032 14.3 1.2 0.093 12.8 0.2 2.2 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Rhodanese PF00581.20 EGF75962.1 - 6.5e-23 81.3 0.1 1.3e-16 61.0 0.1 2.6 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 EGF75962.1 - 5.7e-07 29.7 0.2 1.2e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DSPc PF00782.20 EGF75962.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF75962.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hydrolase_3 PF08282.12 EGF75963.1 - 1.3e-61 208.5 5.9 1.3e-61 208.5 5.9 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DeoRC PF00455.22 EGF75963.1 - 2.5e-32 112.1 1.3 4.5e-32 111.2 0.5 1.8 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EGF75963.1 - 1.9e-15 56.4 1.0 3.5e-15 55.5 0.2 2.0 2 0 0 2 2 1 1 DeoR-like helix-turn-helix domain S6PP PF05116.13 EGF75963.1 - 1.6e-11 44.2 0.5 9.3e-07 28.6 0.1 2.7 3 1 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase HTH_11 PF08279.12 EGF75963.1 - 4.9e-08 32.8 0.4 1.3e-07 31.5 0.4 1.7 1 0 0 1 1 1 1 HTH domain Hydrolase PF00702.26 EGF75963.1 - 1.3e-06 28.9 0.1 0.00064 20.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HTH_23 PF13384.6 EGF75963.1 - 0.0002 21.0 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HAD PF12710.7 EGF75963.1 - 0.00025 21.5 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GntR PF00392.21 EGF75963.1 - 0.00036 20.1 0.0 0.00084 18.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EGF75963.1 - 0.002 17.7 0.4 0.006 16.1 0.4 1.9 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 EGF75963.1 - 0.0069 16.5 0.2 0.022 14.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 EGF75963.1 - 0.0092 16.2 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EGF75963.1 - 0.0094 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 EGF75963.1 - 0.01 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EGF75963.1 - 0.014 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 MarR family DUF977 PF06163.11 EGF75963.1 - 0.019 14.9 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) SpoIIID PF12116.8 EGF75963.1 - 0.034 14.2 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_AsnC-type PF13404.6 EGF75963.1 - 0.039 13.8 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 EGF75963.1 - 0.096 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Mga PF05043.13 EGF75963.1 - 0.098 13.3 0.1 0.098 13.3 0.1 3.6 4 1 1 5 5 3 0 Mga helix-turn-helix domain MMR_HSR1 PF01926.23 EGF75964.1 - 9.6e-16 57.9 0.6 5.3e-15 55.5 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGF75964.1 - 2.1e-13 50.7 1.4 1.9e-07 31.3 0.1 2.6 3 0 0 3 3 3 2 Dynamin family FeoB_N PF02421.18 EGF75964.1 - 6.7e-09 35.5 0.2 1.6e-08 34.2 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGF75964.1 - 7.4e-07 28.9 0.4 6.3e-05 22.6 0.1 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF75964.1 - 5.2e-06 26.5 2.4 0.00019 21.4 0.1 2.7 2 1 0 2 2 2 1 RsgA GTPase DUF697 PF05128.12 EGF75964.1 - 5.2e-06 26.3 0.3 1.7e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF697) MMR_HSR1_Xtn PF16897.5 EGF75964.1 - 0.00012 22.1 0.7 0.00023 21.1 0.7 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AIG1 PF04548.16 EGF75964.1 - 0.0032 16.8 0.4 0.0088 15.4 0.4 1.9 1 1 0 1 1 1 1 AIG1 family Roc PF08477.13 EGF75964.1 - 0.022 15.0 0.0 0.19 11.9 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MnmE_helical PF12631.7 EGF75964.1 - 0.03 14.5 0.1 0.042 14.0 0.1 1.3 1 0 0 1 1 1 0 MnmE helical domain Ras PF00071.22 EGF75964.1 - 0.06 12.9 0.1 0.29 10.7 0.1 2.0 1 1 0 1 1 1 0 Ras family TPR_7 PF13176.6 EGF75965.1 - 0.00051 19.9 0.4 0.49 10.5 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF75965.1 - 0.001 19.1 0.3 0.56 10.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF75965.1 - 0.01 16.1 0.1 0.22 12.0 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF75965.1 - 0.078 13.1 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RTA1 PF04479.13 EGF75966.1 - 0.014 15.0 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 RTA1 like protein BTP PF05232.12 EGF75966.1 - 0.041 13.9 2.0 3.5 7.8 0.8 2.2 2 0 0 2 2 2 0 Chlorhexidine efflux transporter zf-LITAF-like PF10601.9 EGF75967.1 - 5.8e-06 26.5 15.2 1.4e-05 25.3 14.9 1.9 1 1 0 1 1 1 1 LITAF-like zinc ribbon domain AhpC-TSA PF00578.21 EGF75968.1 - 6.2e-31 106.9 0.0 7.9e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGF75968.1 - 3.3e-13 49.6 0.0 4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGF75968.1 - 5e-11 42.3 0.1 1e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF1616 PF07760.11 EGF75970.1 - 0.063 12.7 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) FMN_red PF03358.15 EGF75971.1 - 6.7e-25 87.6 0.0 8.3e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGF75971.1 - 4.4e-06 26.5 0.0 5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold YqcI_YcgG PF08892.11 EGF75972.1 - 2.7e-67 226.7 0.1 3.2e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 YqcI/YcgG family DUF1415 PF07209.12 EGF75972.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) TauE PF01925.19 EGF75973.1 - 1.8e-40 139.1 21.2 2.4e-40 138.6 21.2 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE 5_nucleotid_C PF02872.18 EGF75973.1 - 5.9e-09 36.3 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGF75973.1 - 2.3e-06 28.3 2.4 3.8e-06 27.5 2.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EGF75973.1 - 0.0062 16.0 0.2 0.041 13.3 0.2 2.2 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Rsm22 PF09243.10 EGF75973.1 - 0.08 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DUF3533 PF12051.8 EGF75973.1 - 3.6 6.4 8.5 6.2 5.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Glyco_tranf_2_2 PF10111.9 EGF75974.1 - 3.6e-11 43.1 0.1 7.4e-07 28.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGF75974.1 - 7.4e-11 42.1 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 EGF75974.1 - 1.4e-07 31.0 0.4 3.8e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 EGF75974.1 - 4.5e-05 23.5 0.0 0.11 12.3 0.0 2.3 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_49 PF13896.6 EGF75974.1 - 0.00057 19.3 0.4 0.016 14.6 0.4 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_trans_2_3 PF13632.6 EGF75974.1 - 0.088 12.7 0.1 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGF75975.1 - 2.7e-10 40.3 0.3 3.5e-10 40.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGF75975.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGF75976.1 - 1.5e-08 34.6 0.4 2.4e-08 34.0 0.3 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGF75976.1 - 0.00086 19.3 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.16 EGF75976.1 - 0.005 16.3 0.3 0.0074 15.8 0.3 1.4 1 0 0 1 1 1 1 Fringe-like CsgA PF17334.2 EGF75976.1 - 0.13 13.1 0.6 0.13 13.1 0.6 2.3 2 2 0 2 2 2 0 Minor curli fiber component A Epimerase PF01370.21 EGF75977.1 - 6.9e-55 186.1 0.0 8.2e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF75977.1 - 5.8e-54 183.7 0.0 7.7e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGF75977.1 - 3.1e-21 75.6 0.0 4.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGF75977.1 - 1.6e-19 70.1 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGF75977.1 - 1.8e-16 60.1 0.0 1.4e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGF75977.1 - 1.6e-06 27.7 0.0 3.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EGF75977.1 - 3.8e-06 26.9 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGF75977.1 - 6e-06 25.6 0.3 1.9e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGF75977.1 - 0.00016 21.6 0.0 0.00032 20.7 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EGF75977.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Methyltransf_31 PF13847.6 EGF75977.1 - 0.0086 15.9 0.0 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 EGF75977.1 - 0.037 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.6 EGF75977.1 - 0.08 13.7 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.15 EGF75978.1 - 1.1e-23 83.7 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGF75978.1 - 4.4e-07 29.8 0.1 1.3e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Flavodoxin-like fold PLDc_2 PF13091.6 EGF75978.1 - 0.12 12.2 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 PLD-like domain Flavodoxin_2 PF02525.17 EGF75979.1 - 7.4e-38 130.2 0.1 9e-38 130.0 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EGF75979.1 - 3.6e-09 36.5 0.0 5.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Thioredoxin_4 PF13462.6 EGF75980.1 - 2.5e-38 131.9 0.0 3e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DsbD PF02683.15 EGF75980.1 - 1.9e-14 54.0 2.8 2.6e-14 53.6 2.8 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DSBA PF01323.20 EGF75980.1 - 8.2e-08 32.2 0.3 1.5e-05 24.9 0.3 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 EGF75980.1 - 2.2e-06 27.5 0.2 3e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_12 PF18400.1 EGF75980.1 - 0.0083 16.0 0.2 0.021 14.7 0.2 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain DsbD_2 PF13386.6 EGF75980.1 - 0.048 13.6 3.0 0.073 13.0 3.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Thioredoxin PF00085.20 EGF75980.1 - 0.073 13.1 0.2 7.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 EGF75980.1 - 0.12 12.9 1.2 0.87 10.1 1.2 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGF75980.1 - 0.14 12.3 0.3 0.8 9.8 0.2 2.1 2 0 0 2 2 2 0 Thioredoxin domain Rubredoxin_2 PF18073.1 EGF75980.1 - 0.54 10.0 2.2 0.96 9.2 2.2 1.3 1 0 0 1 1 1 0 Rubredoxin metal binding domain AhpC-TSA PF00578.21 EGF75981.1 - 1.4e-23 83.1 0.0 6.8e-22 77.7 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGF75981.1 - 6.9e-19 68.0 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGF75981.1 - 4.2e-13 49.4 0.0 1.7e-10 41.1 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 EGF75981.1 - 2.5e-08 33.8 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGF75981.1 - 0.0001 22.7 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EGF75981.1 - 0.00036 20.4 0.0 0.00053 19.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein GSHPx PF00255.19 EGF75981.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase SCO1-SenC PF02630.14 EGF75981.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC ABC_tran PF00005.27 EGF75982.1 - 3.4e-33 115.1 0.0 7e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGF75982.1 - 2.4e-08 33.7 0.1 6e-08 32.4 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF75982.1 - 3e-08 33.8 0.1 0.00013 21.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 EGF75982.1 - 9.8e-06 26.3 0.1 3.1e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 MalK OB fold domain RsgA_GTPase PF03193.16 EGF75982.1 - 1.4e-05 25.0 0.2 3.1e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF75982.1 - 0.00039 20.1 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TOBE_2 PF08402.10 EGF75982.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 TOBE domain AAA_22 PF13401.6 EGF75982.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF75982.1 - 0.0024 18.3 0.3 0.0049 17.3 0.1 1.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_23 PF13476.6 EGF75982.1 - 0.0029 18.1 1.7 0.0043 17.6 0.0 2.1 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 EGF75982.1 - 0.013 14.6 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 EGF75982.1 - 0.015 14.5 0.0 0.034 13.3 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase AAA_15 PF13175.6 EGF75982.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGF75982.1 - 0.022 14.4 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGF75982.1 - 0.023 14.9 0.2 0.06 13.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EGF75982.1 - 0.031 13.7 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EGF75982.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGF75982.1 - 0.037 13.9 0.1 0.15 11.9 0.0 2.0 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 EGF75982.1 - 0.074 13.6 0.1 0.27 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGF75982.1 - 0.075 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGF75982.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EGF75982.1 - 0.11 12.1 0.5 0.36 10.4 0.1 2.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 EGF75982.1 - 0.12 11.7 0.3 8.5 5.6 0.2 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MMR_HSR1 PF01926.23 EGF75982.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase BPD_transp_1 PF00528.22 EGF75983.1 - 1e-14 54.7 9.1 1e-14 54.7 9.1 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 EGF75984.1 - 2e-48 165.7 6.1 3.4e-48 164.9 6.1 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EGF75984.1 - 5.3e-28 98.9 5.2 7.5e-28 98.4 5.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EGF75984.1 - 9.6e-05 22.2 0.0 0.00061 19.6 0.0 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein GDPD PF03009.17 EGF75985.1 - 1.6e-70 237.8 5.5 1.7e-35 123.0 0.0 2.9 3 0 0 3 3 3 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EGF75985.1 - 0.00067 19.3 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain Metallophos PF00149.28 EGF75986.1 - 5.4e-14 53.2 0.8 1.4e-13 51.9 0.5 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase GATase_7 PF13537.6 EGF75986.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGF75986.1 - 6.8e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Metallophos_2 PF12850.7 EGF75986.1 - 1.1e-05 25.7 0.0 3.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF3700 PF12481.8 EGF75986.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein NAD_binding_3 PF03447.16 EGF75987.1 - 3.7e-05 24.4 0.1 7.6e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EGF75987.1 - 0.036 14.2 1.7 0.067 13.3 0.6 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus SAF PF08666.12 EGF75987.1 - 0.1 13.3 0.3 0.24 12.1 0.3 1.6 1 0 0 1 1 1 0 SAF domain GTP_EFTU_D4 PF14578.6 EGF75987.1 - 0.13 12.2 3.5 0.91 9.5 0.8 2.6 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Sacchrp_dh_NADP PF03435.18 EGF75987.1 - 0.58 10.4 2.8 18 5.6 2.8 2.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGF75988.1 - 2.5e-31 109.0 0.0 3.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF75988.1 - 2.1e-17 63.5 0.0 3.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGF75988.1 - 1.1e-12 47.7 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGF75988.1 - 2.4e-08 34.1 0.0 3.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGF75988.1 - 3.5e-08 32.8 0.0 5.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF75988.1 - 0.00019 20.7 0.4 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGF75988.1 - 0.0035 16.5 0.4 0.067 12.3 0.3 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGF75988.1 - 0.0054 16.3 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGF75988.1 - 0.0092 15.5 0.2 0.06 12.8 0.1 2.5 2 2 0 2 2 2 1 short chain dehydrogenase dTDP_sugar_isom PF00908.17 EGF75990.1 - 2.9e-75 251.6 0.0 3.3e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase NTP_transferase PF00483.23 EGF75991.1 - 6.4e-68 229.0 0.0 8.2e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGF75991.1 - 2.3e-09 37.8 0.0 2.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGF75991.1 - 0.0035 17.1 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase AHSA1 PF08327.11 EGF75992.1 - 1.1e-07 32.1 0.1 1.8e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EGF75992.1 - 0.035 14.4 0.4 0.12 12.7 0.4 1.9 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABC_tran PF00005.27 EGF75993.1 - 2.4e-30 105.8 0.0 3.1e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF75993.1 - 1.9e-12 47.6 0.5 1.5e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGF75993.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EGF75993.1 - 0.0006 19.6 1.7 0.0017 18.2 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EGF75993.1 - 0.0006 19.8 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase PF06745.13 EGF75993.1 - 0.0015 17.9 0.2 0.028 13.8 0.2 2.1 1 1 0 1 1 1 1 KaiC AAA_29 PF13555.6 EGF75993.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 EGF75993.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF75993.1 - 0.0059 17.0 0.0 0.0071 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGF75993.1 - 0.011 16.3 0.1 0.018 15.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGF75993.1 - 0.013 16.0 0.4 0.039 14.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGF75993.1 - 0.017 15.4 0.1 0.035 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGF75993.1 - 0.039 13.9 0.0 1.3 8.9 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EGF75993.1 - 0.044 13.9 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF75993.1 - 0.053 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF75993.1 - 0.057 13.8 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGF75993.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EGF75993.1 - 0.085 13.0 0.1 0.19 11.8 0.1 1.8 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGF75993.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGF75993.1 - 0.12 12.5 0.1 0.28 11.2 0.1 1.6 1 1 0 1 1 1 0 Dynamin family NB-ARC PF00931.22 EGF75993.1 - 0.12 11.6 0.8 1.2 8.3 0.2 2.8 2 2 2 4 4 4 0 NB-ARC domain Cytidylate_kin PF02224.18 EGF75993.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 EGF75993.1 - 0.16 11.7 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC2_membrane_3 PF12698.7 EGF75994.1 - 1.3e-38 133.1 12.1 1.7e-38 132.6 12.1 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EGF75994.1 - 1.1e-29 103.4 21.0 1.1e-29 103.4 21.0 2.2 3 0 0 3 3 3 1 ABC-2 type transporter TetR_N PF00440.23 EGF75994.1 - 1e-18 66.9 0.6 1.6e-18 66.2 0.6 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family ABC2_membrane_2 PF12679.7 EGF75994.1 - 2.4e-15 56.6 4.4 2.9e-15 56.3 3.3 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein TetR_C_7 PF14246.6 EGF75994.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_11 PF16859.5 EGF75994.1 - 9.1e-05 22.7 0.0 0.00018 21.8 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 EGF75994.1 - 0.021 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_10 PF16295.5 EGF75994.1 - 0.023 15.0 0.5 0.08 13.2 0.5 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HrcA_DNA-bdg PF03444.15 EGF75994.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_40 PF14493.6 EGF75994.1 - 0.12 12.8 0.6 0.88 10.1 0.1 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain Tetraspanin PF00335.20 EGF75994.1 - 0.4 10.3 5.2 0.53 9.9 4.4 1.6 2 0 0 2 2 2 0 Tetraspanin family ABC2_membrane_4 PF12730.7 EGF75994.1 - 1.7 8.5 20.3 0.26 11.2 14.8 2.4 3 1 0 3 3 3 0 ABC-2 family transporter protein TipAS PF07739.13 EGF75995.1 - 1.2e-35 122.6 2.4 1.2e-35 122.6 2.4 1.9 2 1 0 2 2 2 1 TipAS antibiotic-recognition domain MerR_1 PF13411.6 EGF75995.1 - 2.5e-14 53.1 0.4 5.2e-14 52.1 0.4 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EGF75995.1 - 5e-12 45.4 0.3 8.2e-12 44.7 0.3 1.4 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 EGF75995.1 - 2.2e-06 28.1 0.5 0.00042 20.8 0.1 2.4 2 0 0 2 2 2 1 MerR, DNA binding DUF1048 PF06304.11 EGF75995.1 - 0.064 13.7 1.7 11 6.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1048) DUF496 PF04363.12 EGF75995.1 - 0.17 11.9 2.5 0.16 12.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF496) DUF1910 PF08928.10 EGF75995.1 - 0.31 11.0 3.1 1.2 9.1 3.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) DUF2408 PF10303.9 EGF75995.1 - 0.51 10.9 3.8 2.2 8.9 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TMP-TENI PF02581.17 EGF75996.1 - 6.2e-55 185.3 0.0 6.9e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase DHO_dh PF01180.21 EGF75996.1 - 0.0032 16.7 0.6 0.0081 15.4 0.2 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 EGF75996.1 - 0.0039 16.5 1.7 0.014 14.7 0.3 2.3 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGF75996.1 - 0.05 12.7 0.3 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) HK PF02110.15 EGF75997.1 - 6.5e-79 264.8 6.7 2.1e-78 263.1 3.4 2.0 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EGF75997.1 - 8e-31 107.3 3.2 1.1e-21 77.3 0.0 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EGF75997.1 - 1.2e-08 34.7 2.6 1.9e-08 34.1 2.1 1.4 1 1 0 1 1 1 1 Carbohydrate kinase CAP PF00188.26 EGF75998.1 - 6.2e-11 43.2 0.7 4.8e-10 40.4 0.7 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EGF75999.1 - 3.8e-10 40.7 2.5 7.2e-10 39.8 0.1 2.6 2 2 0 2 2 2 1 Cysteine-rich secretory protein family LAP1C PF05609.12 EGF75999.1 - 0.37 9.8 14.1 0.44 9.6 14.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 EGF75999.1 - 1.8 6.8 26.2 2.2 6.5 26.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 EGF75999.1 - 4.5 7.8 11.8 6.5 7.3 11.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2151 PF10221.9 EGF75999.1 - 8 4.9 17.8 10 4.6 17.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CAP PF00188.26 EGF76000.1 - 1.2e-19 71.4 2.2 1.4e-19 71.2 2.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DnaJ-X PF14308.6 EGF76002.1 - 0.059 12.8 0.1 0.49 9.8 0.3 2.0 2 0 0 2 2 2 0 X-domain of DnaJ-containing AAA_11 PF13086.6 EGF76003.1 - 0.0096 15.7 0.5 0.017 14.9 0.5 1.4 1 0 0 1 1 1 1 AAA domain DUF4820 PF16091.5 EGF76003.1 - 0.031 13.6 0.1 0.031 13.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) PSII_Pbs27 PF13326.6 EGF76003.1 - 0.095 13.0 2.8 0.28 11.5 0.4 2.5 2 1 0 2 2 2 0 Photosystem II Pbs27 Ntox15 PF15604.6 EGF76003.1 - 0.28 11.3 2.2 14 5.8 0.1 2.4 2 1 0 2 2 2 0 Novel toxin 15 DUF573 PF04504.14 EGF76003.1 - 0.76 10.5 8.1 25 5.6 4.5 3.5 2 2 1 3 3 3 0 Protein of unknown function, DUF573 G3P_antiterm PF04309.12 EGF76004.1 - 5.5e-31 107.3 0.0 2.1e-29 102.2 0.0 1.9 1 1 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator adh_short_C2 PF13561.6 EGF76005.1 - 1.3e-54 185.3 2.1 1.6e-54 185.0 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF76005.1 - 1.8e-51 174.4 3.0 2.1e-51 174.2 3.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF76005.1 - 4.9e-10 39.6 1.3 6.3e-10 39.2 1.3 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGF76005.1 - 3.8e-07 29.8 0.1 4.8e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NanE PF04131.14 EGF76005.1 - 0.049 12.8 0.4 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase 2-Hacid_dh_C PF02826.19 EGF76006.1 - 4.7e-56 189.0 0.0 5.8e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGF76006.1 - 2.7e-13 49.7 0.0 6.1e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EGF76006.1 - 0.0048 17.0 1.1 0.01 15.9 1.2 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short_C2 PF13561.6 EGF76007.1 - 3.5e-68 229.7 4.4 4.2e-68 229.4 4.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF76007.1 - 4.7e-54 182.8 4.2 5.6e-54 182.6 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF76007.1 - 2.3e-09 37.4 1.2 4.4e-09 36.5 1.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF76007.1 - 6.9e-07 29.0 0.2 1.5e-06 27.9 0.3 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF76007.1 - 6.3e-06 25.4 1.3 8e-06 25.0 1.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGF76007.1 - 0.0012 18.0 0.3 0.0017 17.5 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N PF00107.26 EGF76007.1 - 0.0014 18.6 0.5 0.0028 17.6 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EGF76007.1 - 0.0019 17.5 0.5 0.04 13.2 0.1 2.4 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGF76007.1 - 0.009 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EGF76007.1 - 0.046 13.3 0.5 0.072 12.6 0.5 1.3 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EGF76007.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Dak1 PF02733.17 EGF76008.1 - 1.9e-113 378.5 0.5 2.1e-113 378.3 0.5 1.0 1 0 0 1 1 1 1 Dak1 domain BsuPI PF12690.7 EGF76009.1 - 7.3e-26 90.1 0.2 1.1e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 Intracellular proteinase inhibitor DUF3324 PF11797.8 EGF76009.1 - 0.002 18.1 0.0 0.0061 16.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function C-terminal (DUF3324) SBD PF17882.1 EGF76009.1 - 0.03 14.1 0.1 0.047 13.5 0.1 1.4 1 1 0 1 1 1 0 OAA-family lectin sugar binding domain Y_Y_Y PF07495.13 EGF76009.1 - 0.042 13.8 0.4 0.16 11.9 0.4 2.1 1 1 0 1 1 1 0 Y_Y_Y domain Wzt_C PF14524.6 EGF76009.1 - 0.047 13.7 0.1 0.13 12.3 0.1 1.8 1 1 1 2 2 2 0 Wzt C-terminal domain FctA PF12892.7 EGF76009.1 - 3.7 8.4 11.3 12 6.8 11.3 2.0 1 1 0 1 1 1 0 Spy0128-like isopeptide containing domain Peptidase_S8 PF00082.22 EGF76010.1 - 5.1e-57 193.4 0.9 8.3e-57 192.7 0.9 1.3 1 0 0 1 1 1 1 Subtilase family CW_binding_2 PF04122.12 EGF76010.1 - 3.6e-53 178.1 7.5 3.7e-17 62.7 0.1 3.7 3 0 0 3 3 3 3 Putative cell wall binding repeat 2 Inhibitor_I9 PF05922.16 EGF76010.1 - 4.3e-07 30.5 1.9 1.2e-06 29.0 1.9 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EGF76011.1 - 8.4e-54 182.8 4.9 8.4e-54 182.8 4.9 1.7 2 0 0 2 2 2 1 Subtilase family CW_binding_2 PF04122.12 EGF76011.1 - 2e-47 159.7 10.5 4.8e-16 59.2 0.1 4.1 4 0 0 4 4 4 3 Putative cell wall binding repeat 2 Inhibitor_I9 PF05922.16 EGF76011.1 - 0.00024 21.7 2.1 0.00059 20.5 2.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1213 PF06740.12 EGF76011.1 - 0.1 13.2 1.1 0.3 11.7 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) DUF4969 PF16339.5 EGF76011.1 - 0.62 10.4 2.4 5.4 7.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Attacin_N PF03768.15 EGF76011.1 - 1.7 8.9 7.2 1.7 8.8 0.4 4.0 5 0 0 5 5 5 0 Attacin, N-terminal region DUF2207 PF09972.9 EGF76012.1 - 4.3 6.0 4.6 4.7 5.9 4.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FGGY_N PF00370.21 EGF76013.1 - 6.8e-63 212.5 0.1 8.9e-63 212.1 0.1 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGF76013.1 - 9.9e-30 103.7 0.0 1.4e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EGF76013.1 - 4.9e-07 29.5 0.0 0.00015 21.3 0.0 2.3 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family SEF14_adhesin PF06443.11 EGF76013.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 SEF14-like adhesin SplA PF11132.8 EGF76013.1 - 0.056 13.2 0.1 0.22 11.3 0.2 1.9 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) adh_short_C2 PF13561.6 EGF76014.1 - 2.5e-39 135.2 0.0 3.9e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF76014.1 - 3.2e-31 108.3 0.0 5.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Lar_N PF09861.9 EGF76014.1 - 2e-08 33.7 1.0 2e-08 33.7 1.0 1.8 2 0 0 2 2 2 1 Lactate racemase N-terminal domain DUF362 PF04015.12 EGF76014.1 - 7.7e-05 23.0 0.1 0.00015 22.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF362) GFO_IDH_MocA PF01408.22 EGF76015.1 - 0.011 16.6 0.0 0.012 16.5 0.0 1.0 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AP_endonuc_2 PF01261.24 EGF76016.1 - 1.2e-16 60.8 0.1 7.1e-16 58.3 0.1 1.9 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel ComA PF02679.15 EGF76016.1 - 0.048 13.1 0.2 7.6 5.9 0.1 2.9 2 1 1 3 3 3 0 (2R)-phospho-3-sulfolactate synthase (ComA) GFO_IDH_MocA PF01408.22 EGF76017.1 - 1.3e-22 80.9 0.1 7e-22 78.5 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGF76017.1 - 2.2e-07 30.9 0.1 4.1e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 EGF76017.1 - 0.0015 18.8 0.2 0.023 14.9 0.2 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGF76017.1 - 0.0029 18.0 0.0 0.0057 17.1 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EGF76017.1 - 0.011 16.4 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain PglD_N PF17836.1 EGF76017.1 - 0.14 12.8 0.5 0.43 11.2 0.0 2.1 3 0 0 3 3 3 0 PglD N-terminal domain GFO_IDH_MocA_C PF02894.17 EGF76018.1 - 2.5e-12 46.8 0.2 8.5e-12 45.1 0.2 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EGF76018.1 - 2e-11 44.8 0.0 3.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGF76018.1 - 0.0095 16.6 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain FHIPEP PF00771.20 EGF76021.1 - 0.0085 14.6 0.1 0.0085 14.6 0.1 1.1 1 0 0 1 1 1 1 FHIPEP family LEAP-2 PF07359.11 EGF76021.1 - 0.022 14.6 0.1 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) COX16 PF14138.6 EGF76021.1 - 0.027 15.0 0.2 1.1 9.9 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 AIRC PF00731.20 EGF76021.1 - 0.032 13.8 0.1 0.051 13.1 0.1 1.4 1 1 0 1 1 1 0 AIR carboxylase Ntox23 PF15528.6 EGF76021.1 - 0.049 13.8 0.6 0.07 13.3 0.6 1.2 1 0 0 1 1 1 0 Bacterial toxin 23 Borrelia_rep PF03183.13 EGF76021.1 - 0.082 12.9 0.2 0.082 12.9 0.2 1.9 2 0 0 2 2 2 0 Borrelia repeat protein EIIBC-GUT_N PF03612.14 EGF76021.1 - 0.24 11.1 3.9 0.17 11.6 2.5 1.4 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Conotoxin PF02950.17 EGF76021.1 - 1 10.4 4.1 4.9 8.2 1.3 2.1 2 0 0 2 2 2 0 Conotoxin DUF3481 PF11980.8 EGF76022.1 - 0.035 13.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein APG6_N PF17675.1 EGF76022.1 - 7.3 7.1 12.3 3.6 8.1 1.1 2.4 3 0 0 3 3 3 0 Apg6 coiled-coil region DASH_Spc34 PF08657.10 EGF76023.1 - 0.0056 16.5 1.3 0.0075 16.1 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Cep57_CLD PF14073.6 EGF76023.1 - 0.034 14.2 12.2 0.44 10.6 1.9 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Lectin_N PF03954.14 EGF76023.1 - 0.39 10.4 3.5 0.88 9.3 3.4 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain FapA PF03961.13 EGF76023.1 - 0.47 9.0 4.4 0.59 8.7 4.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Spc34 PF08657.10 EGF76024.1 - 0.0026 17.6 1.3 0.0038 17.1 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Jnk-SapK_ap_N PF09744.9 EGF76024.1 - 0.05 13.8 3.4 0.083 13.1 3.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4404 PF14357.6 EGF76024.1 - 0.2 12.3 1.8 0.45 11.2 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) MAD PF05557.13 EGF76025.1 - 0.0057 15.1 6.9 0.0094 14.4 6.9 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.9 EGF76025.1 - 0.0072 16.6 9.2 0.013 15.8 9.2 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EGF76025.1 - 0.05 14.1 6.7 0.037 14.5 5.2 1.5 2 0 0 2 2 2 0 Fez1 Cep57_CLD PF14073.6 EGF76025.1 - 0.083 12.9 13.7 1 9.4 2.3 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Pil1 PF13805.6 EGF76025.1 - 0.15 11.5 3.8 0.28 10.6 3.8 1.4 1 0 0 1 1 1 0 Eisosome component PIL1 DUF1664 PF07889.12 EGF76025.1 - 0.2 11.7 2.4 0.39 10.8 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EGF76025.1 - 0.46 10.9 6.6 1.3 9.5 0.2 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EGF76025.1 - 2.2 7.4 8.8 3.1 7.0 8.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EGF76025.1 - 5.3 5.5 7.9 7.4 5.0 7.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A P68HR PF08061.11 EGF76025.1 - 8.2 6.7 7.5 22 5.3 0.6 2.3 2 0 0 2 2 2 0 P68HR (NUC004) repeat HTH_18 PF12833.7 EGF76026.1 - 6.1e-18 64.9 0.2 2e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EGF76026.1 - 4.3e-12 45.8 5.0 8.1e-07 29.0 0.1 3.3 4 0 0 4 4 4 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_24 PF13412.6 EGF76026.1 - 0.032 13.8 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.16 EGF76027.1 - 7.4e-51 173.1 40.6 7.4e-51 173.1 40.6 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF76027.1 - 2.6e-14 53.0 36.1 2.3e-11 43.2 11.7 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Glycophorin_A PF01102.18 EGF76027.1 - 0.42 10.9 4.5 5.1 7.4 0.4 2.8 2 1 0 2 2 2 0 Glycophorin A YfhO PF09586.10 EGF76027.1 - 0.8 7.9 9.8 0.11 10.8 5.6 1.6 1 1 1 2 2 2 0 Bacterial membrane protein YfhO PUCC PF03209.15 EGF76027.1 - 1.7 7.6 44.3 0.079 11.9 25.2 2.6 1 1 1 2 2 2 0 PUCC protein UL42 PF17638.2 EGF76027.1 - 1.7 8.6 12.0 0.63 10.0 0.4 3.5 2 1 1 3 3 3 0 HCMV UL42 Peptidase_M20 PF01546.28 EGF76028.1 - 8.6e-30 104.0 0.2 1.1e-29 103.6 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGF76028.1 - 1.2e-07 31.7 0.0 4.3e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Abhydrolase_1 PF00561.20 EGF76029.1 - 1.5e-22 80.5 0.1 9.4e-22 77.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF76029.1 - 4.5e-11 43.8 0.0 5.9e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF76029.1 - 1.8e-09 37.3 0.0 1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EGF76029.1 - 2.5e-05 24.0 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGF76029.1 - 0.00011 21.8 0.0 0.0087 15.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EGF76029.1 - 0.00015 21.8 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 EGF76029.1 - 0.00029 21.0 0.0 0.00052 20.2 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGF76029.1 - 0.0014 18.4 0.3 0.015 15.1 0.3 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 EGF76029.1 - 0.0054 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGF76029.1 - 0.0099 15.6 0.0 0.056 13.1 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Palm_thioest PF02089.15 EGF76029.1 - 0.011 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_S15 PF02129.18 EGF76029.1 - 0.03 13.9 0.1 0.084 12.4 0.1 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EGF76029.1 - 0.05 13.4 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.11 EGF76029.1 - 0.092 12.6 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal P22_Cro PF14549.6 EGF76029.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Ndr PF03096.14 EGF76029.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family Oxidored_FMN PF00724.20 EGF76030.1 - 1.1e-79 268.2 0.0 1.4e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EGF76030.1 - 0.047 13.1 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF4246 PF14033.6 EGF76032.1 - 2.7e-28 99.3 0.1 3.7e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) NTS PF15447.6 EGF76032.1 - 0.12 12.9 0.0 14 6.3 0.0 2.3 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 BpuSI_N PF15516.6 EGF76032.1 - 0.15 12.0 0.3 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 BpuSI N-terminal domain LRR_4 PF12799.7 EGF76033.1 - 1e-16 60.8 10.8 2.6e-08 34.0 0.6 5.0 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF76033.1 - 2.5e-11 43.2 12.7 4.5e-07 29.5 1.9 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 EGF76033.1 - 1.7e-08 34.2 1.7 9.5e-07 28.5 0.1 2.9 2 1 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 EGF76033.1 - 8e-05 22.4 1.5 1.5 9.1 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 EGF76033.1 - 0.00035 20.7 4.3 10 7.1 0.1 5.3 4 0 0 4 4 4 2 Leucine Rich Repeat MDMPI_C PF07398.11 EGF76034.1 - 0.036 14.9 0.5 0.05 14.5 0.5 1.2 1 0 0 1 1 1 0 MDMPI C-terminal domain Fungus-induced PF10917.8 EGF76034.1 - 0.098 13.0 3.2 0.099 13.0 0.0 2.3 2 1 1 3 3 3 0 Fungus-induced protein YjbE PF11106.8 EGF76034.1 - 0.55 10.5 7.8 0.31 11.3 3.4 2.0 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Tyrosinase PF00264.20 EGF76035.1 - 1.4e-34 120.3 2.6 7.1e-33 114.8 2.6 2.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Fungus-induced PF10917.8 EGF76036.1 - 0.019 15.3 0.8 0.12 12.7 0.8 2.1 1 1 0 1 1 1 0 Fungus-induced protein MDMPI_C PF07398.11 EGF76037.1 - 0.036 14.9 0.5 0.05 14.5 0.5 1.2 1 0 0 1 1 1 0 MDMPI C-terminal domain Fungus-induced PF10917.8 EGF76037.1 - 0.098 13.0 3.2 0.099 13.0 0.0 2.3 2 1 1 3 3 3 0 Fungus-induced protein YjbE PF11106.8 EGF76037.1 - 0.55 10.5 7.8 0.31 11.3 3.4 2.0 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Peptidase_M18 PF02127.15 EGF76038.1 - 5.1e-167 556.0 0.0 5.8e-167 555.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGF76038.1 - 0.00026 20.1 0.1 0.088 11.8 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Helicase_C PF00271.31 EGF76039.1 - 2.8e-07 30.9 0.1 1e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGF76040.1 - 0.0048 17.6 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) RPA_interact_M PF14767.6 EGF76040.1 - 0.025 15.2 0.5 2.1 9.0 0.0 2.7 2 1 0 2 2 2 0 Replication protein A interacting middle DnaB_2 PF07261.11 EGF76041.1 - 3.6e-14 52.3 0.0 8e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Replication initiation and membrane attachment HTH_36 PF13730.6 EGF76041.1 - 0.035 14.0 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DnaB_C PF03796.15 EGF76042.1 - 1.8e-89 299.4 0.0 3.8e-89 298.4 0.0 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DnaB PF00772.21 EGF76042.1 - 2.3e-19 69.4 0.7 4.8e-19 68.4 0.3 1.8 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 EGF76042.1 - 1.4e-09 37.8 0.0 2.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGF76042.1 - 0.00038 19.9 0.8 0.00081 18.8 0.0 1.9 2 1 0 2 2 2 1 KaiC Rubrerythrin PF02915.17 EGF76042.1 - 0.93 9.9 4.6 3 8.3 0.5 2.5 1 1 1 2 2 2 0 Rubrerythrin DUF5571 PF17732.1 EGF76043.1 - 0.022 14.2 0.2 0.027 13.9 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5571) AAA_5 PF07728.14 EGF76044.1 - 4.3e-24 85.1 0.1 1.6e-23 83.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGF76044.1 - 9.1e-06 26.1 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF76044.1 - 0.00025 20.6 0.4 0.0013 18.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region PhoH PF02562.16 EGF76044.1 - 0.00041 19.9 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_14 PF13173.6 EGF76044.1 - 0.0011 19.0 1.7 0.0028 17.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGF76044.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGF76044.1 - 0.0035 17.2 0.0 0.052 13.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGF76044.1 - 0.0041 16.7 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF76044.1 - 0.005 17.1 0.0 0.016 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGF76044.1 - 0.014 15.4 0.2 0.055 13.5 0.1 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EGF76044.1 - 0.018 14.5 0.0 0.039 13.3 0.0 1.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PrgU PF09627.10 EGF76044.1 - 0.032 14.2 0.1 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 PrgU-like protein NACHT PF05729.12 EGF76044.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGF76044.1 - 0.089 13.2 0.7 0.28 11.6 0.0 2.2 3 0 0 3 3 2 0 RNA helicase AAA_19 PF13245.6 EGF76044.1 - 0.12 12.7 0.1 0.58 10.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGF76044.1 - 0.16 12.4 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EGF76044.1 - 0.26 11.0 0.0 0.51 10.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kelch_3 PF13415.6 EGF76045.1 - 0.024 14.9 5.5 5 7.5 0.2 4.4 4 1 0 4 4 4 0 Galactose oxidase, central domain VCBS PF13517.6 EGF76045.1 - 0.17 12.5 8.6 0.44 11.2 0.7 4.1 3 2 2 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella ADH_zinc_N PF00107.26 EGF76047.1 - 1.9e-19 69.9 0.2 3.2e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGF76047.1 - 6.7e-17 61.3 2.4 4.3e-16 58.7 2.3 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGF76047.1 - 1.2e-08 36.1 0.0 2.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGF76047.1 - 0.00042 19.7 0.8 0.00086 18.7 0.4 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGF76047.1 - 0.0013 18.0 1.4 0.0024 17.2 1.4 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Arc_PepC PF06819.11 EGF76047.1 - 0.0054 16.9 0.2 1.6 8.9 0.1 2.6 2 0 0 2 2 2 1 Archaeal Peptidase A24 C-terminal Domain NAD_binding_2 PF03446.15 EGF76047.1 - 0.0062 16.7 1.5 0.014 15.6 0.3 2.3 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glu_dehyd_C PF16912.5 EGF76047.1 - 0.014 14.9 0.8 0.022 14.3 0.8 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF2855 PF11017.8 EGF76047.1 - 0.017 14.9 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Met_10 PF02475.16 EGF76047.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein F420_oxidored PF03807.17 EGF76047.1 - 0.034 14.7 0.9 0.034 14.7 0.9 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent N6_Mtase PF02384.16 EGF76048.1 - 2.3e-47 161.8 0.1 2.7e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 N-6 DNA Methylase MTS PF05175.14 EGF76048.1 - 0.00051 19.6 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EGF76048.1 - 0.048 13.3 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 EGF76048.1 - 0.057 13.1 1.0 0.2 11.3 1.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Response_reg PF00072.24 EGF76049.1 - 0.0059 16.8 0.0 0.0094 16.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Polysacc_deac_1 PF01522.21 EGF76050.1 - 9.2e-29 99.9 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EGF76050.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase MerR_1 PF13411.6 EGF76051.1 - 2.1e-18 66.1 0.6 4e-18 65.3 0.6 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 EGF76051.1 - 4.9e-14 51.8 0.0 1.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 EGF76051.1 - 0.00058 20.0 0.3 0.0014 18.8 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EGF76051.1 - 0.0032 17.5 0.1 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 EGF76051.1 - 0.0055 16.5 1.1 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 EGF76051.1 - 0.008 16.3 0.4 0.029 14.5 0.3 2.1 1 1 2 3 3 3 1 Helix-turn-helix of insertion element transposase IZUMO PF15005.6 EGF76051.1 - 0.011 16.2 0.4 3.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated HTH_Tnp_1 PF01527.20 EGF76051.1 - 0.023 15.0 1.2 0.03 14.6 0.1 1.7 2 0 0 2 2 2 0 Transposase DUF1836 PF08876.11 EGF76051.1 - 0.033 14.2 0.0 0.061 13.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1836) VRP1 PF03538.14 EGF76051.1 - 0.035 13.5 0.2 0.044 13.2 0.2 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein RelE PF06296.12 EGF76051.1 - 0.056 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system CENP-B_N PF04218.13 EGF76051.1 - 0.066 12.9 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain MGS PF02142.22 EGF76051.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 MGS-like domain Apolipoprotein PF01442.18 EGF76052.1 - 0.0094 15.8 5.4 0.013 15.4 5.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4364 PF14277.6 EGF76052.1 - 0.11 12.3 7.2 0.21 11.3 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) YtxH PF12732.7 EGF76052.1 - 0.75 10.4 13.4 5.1e+02 1.3 13.0 2.8 1 1 0 1 1 1 0 YtxH-like protein ALMT PF11744.8 EGF76052.1 - 9.8 4.9 11.8 13 4.5 11.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Gas_vesicle PF00741.18 EGF76053.1 - 1.5e-16 60.3 5.9 1.9e-16 59.9 5.9 1.2 1 0 0 1 1 1 1 Gas vesicle protein UTRA PF07702.13 EGF76053.1 - 0.055 13.3 0.1 0.065 13.1 0.1 1.1 1 0 0 1 1 1 0 UTRA domain TENA_THI-4 PF03070.16 EGF76053.1 - 0.18 11.6 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 TENA/THI-4/PQQC family GvpO PF05800.11 EGF76054.1 - 5.3e-08 32.7 0.1 6.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpO DUF2185 PF09951.9 EGF76054.1 - 0.0052 16.6 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) DUF1654 PF07867.11 EGF76054.1 - 0.019 14.7 0.2 0.029 14.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Cir_Bir_Yir PF06022.11 EGF76054.1 - 0.078 12.5 0.6 0.092 12.2 0.6 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir AAA_5 PF07728.14 EGF76055.1 - 3e-20 72.6 0.0 2.3e-19 69.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGF76055.1 - 4.5e-08 33.0 0.0 1.7e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGF76055.1 - 8.6e-05 23.0 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF76055.1 - 0.00079 19.8 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGF76055.1 - 0.0036 17.1 0.0 0.036 13.8 0.0 2.1 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF76055.1 - 0.0041 17.4 0.0 0.0091 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGF76055.1 - 0.0047 17.1 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGF76055.1 - 0.0078 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGF76055.1 - 0.012 16.1 0.1 0.032 14.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 EGF76055.1 - 0.019 14.7 0.0 0.053 13.2 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EGF76055.1 - 0.026 14.4 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EGF76055.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EGF76055.1 - 0.035 13.8 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGF76055.1 - 0.039 13.9 0.1 0.075 12.9 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGF76055.1 - 0.043 14.2 0.0 0.21 12.0 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EGF76055.1 - 0.046 13.8 0.0 0.097 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain CbbQ_C PF08406.10 EGF76055.1 - 0.048 13.9 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal NTPase_1 PF03266.15 EGF76055.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EGF76055.1 - 0.073 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGF76055.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF76055.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1320 PF07030.12 EGF76055.1 - 0.13 12.4 0.5 3.5 7.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1320) DXP_synthase_N PF13292.6 EGF76055.1 - 0.14 11.3 0.0 0.65 9.1 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase GvpL_GvpF PF06386.11 EGF76056.1 - 1.7e-97 326.1 0.2 2.9e-48 164.9 0.2 2.1 2 0 0 2 2 2 2 Gas vesicle synthesis protein GvpL/GvpF GvpG PF05120.12 EGF76056.1 - 1.9e-08 34.2 6.2 1.9e-08 34.2 6.2 2.6 2 0 0 2 2 2 1 Gas vesicle protein G CdvA PF18822.1 EGF76056.1 - 8.8 6.2 20.7 0.077 12.8 9.0 3.3 3 1 0 3 3 3 0 CdvA-like coiled-coil domain GvpK PF05121.12 EGF76057.1 - 9.2e-34 115.3 6.6 1.1e-33 115.1 6.6 1.1 1 0 0 1 1 1 1 Gas vesicle protein K Gas_vesicle PF00741.18 EGF76058.1 - 4.2e-16 58.8 10.0 5.9e-16 58.3 10.0 1.2 1 0 0 1 1 1 1 Gas vesicle protein TSA PF03249.13 EGF76058.1 - 0.023 13.5 0.1 0.024 13.5 0.1 1.0 1 0 0 1 1 1 0 Type specific antigen KIAA1430 PF13879.6 EGF76058.1 - 0.027 15.2 1.0 0.028 15.2 1.0 1.2 1 1 0 1 1 1 0 KIAA1430 homologue YtxH PF12732.7 EGF76059.1 - 3.4e-17 62.7 1.6 3.4e-17 62.7 1.6 2.3 3 0 0 3 3 3 1 YtxH-like protein LEA_4 PF02987.16 EGF76059.1 - 7.7e-09 35.5 6.1 2.4e-08 33.9 6.1 1.9 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2407_C PF13373.6 EGF76059.1 - 0.39 10.9 0.1 0.39 10.9 0.1 2.6 1 1 2 3 3 3 0 DUF2407 C-terminal domain PPP4R2 PF09184.11 EGF76059.1 - 3.3 7.2 21.2 3.9 7.0 21.2 1.1 1 0 0 1 1 1 0 PPP4R2 Macoilin PF09726.9 EGF76059.1 - 8 4.9 20.1 8.6 4.8 20.1 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 EGF76059.1 - 8.5 3.4 15.2 8.4 3.4 15.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TetR_N PF00440.23 EGF76060.1 - 1.9e-15 56.3 0.1 3.1e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_3 PF01381.22 EGF76060.1 - 0.0024 17.9 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_11 PF08279.12 EGF76060.1 - 0.0031 17.4 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_Tnp_1_2 PF13022.6 EGF76060.1 - 0.0039 17.3 1.5 0.0049 17.0 0.8 1.7 2 1 0 2 2 2 1 Helix-turn-helix of insertion element transposase HTH_22 PF13309.6 EGF76060.1 - 0.008 16.2 0.0 0.026 14.6 0.1 1.9 2 0 0 2 2 2 1 HTH domain HTH_40 PF14493.6 EGF76060.1 - 0.0093 16.4 0.1 0.02 15.3 0.1 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_6 PF01418.17 EGF76060.1 - 0.041 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_7 PF02796.15 EGF76060.1 - 0.067 13.3 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EGF76060.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain TnsD PF15978.5 EGF76060.1 - 0.12 11.3 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Terminase_5 PF06056.12 EGF76060.1 - 0.14 12.1 0.1 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) ABC2_membrane PF01061.24 EGF76061.1 - 0.0018 17.7 39.8 0.016 14.7 8.4 3.2 2 1 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EGF76061.1 - 0.002 17.4 9.7 0.002 17.4 9.7 3.6 2 1 0 2 2 2 1 ABC-2 family transporter protein Phage_holin_2_3 PF16080.5 EGF76061.1 - 0.099 12.4 0.9 0.92 9.3 0.0 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 ABC_tran PF00005.27 EGF76062.1 - 5.4e-26 91.7 0.0 1.1e-25 90.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF76062.1 - 3.6e-14 53.3 0.0 3.4e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EGF76062.1 - 1.2e-06 29.1 0.0 2.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 EGF76062.1 - 0.00036 21.1 0.1 0.00053 20.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGF76062.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGF76062.1 - 0.0019 17.9 0.1 0.0051 16.5 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGF76062.1 - 0.043 13.2 0.1 2 7.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 EGF76062.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF76062.1 - 0.086 12.6 0.3 0.38 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGF76062.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Aminotran_5 PF00266.19 EGF76063.1 - 5.3e-13 48.7 0.0 7.2e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Malate_synthase PF01274.22 EGF76064.1 - 1.5e-167 558.0 2.3 1.8e-167 557.8 2.3 1.0 1 0 0 1 1 1 1 Malate synthase HTH_11 PF08279.12 EGF76064.1 - 0.097 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain CCG PF02754.16 EGF76065.1 - 2e-29 101.6 1.0 2.1e-13 50.3 0.7 2.6 2 0 0 2 2 2 2 Cysteine-rich domain FAD_binding_4 PF01565.23 EGF76065.1 - 1.3e-28 99.5 0.5 6.6e-28 97.2 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain Fer4_8 PF13183.6 EGF76065.1 - 2.3e-11 44.0 5.8 4.9e-11 42.9 5.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EGF76065.1 - 2.4e-11 44.0 6.0 5.7e-11 42.8 6.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGF76065.1 - 1.7e-08 34.9 7.9 4.4e-08 33.6 7.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGF76065.1 - 4.3e-08 33.2 7.4 9.3e-08 32.1 7.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGF76065.1 - 6.2e-08 32.7 4.1 0.0056 16.8 0.6 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EGF76065.1 - 9.5e-06 25.2 12.8 0.0027 17.4 2.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGF76065.1 - 5.6e-05 23.0 13.8 0.026 14.6 2.4 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EGF76065.1 - 0.00011 23.1 7.3 0.00036 21.4 7.3 2.0 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 EGF76065.1 - 0.00014 21.8 16.6 0.044 13.9 4.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGF76065.1 - 0.0002 21.6 11.1 0.094 13.3 2.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 EGF76065.1 - 0.0067 16.6 8.3 0.57 10.4 1.1 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EGF76065.1 - 0.19 12.7 18.2 0.88 10.7 6.2 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EGF76065.1 - 1.3 9.9 7.0 6.7 7.6 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 EGF76065.1 - 1.6 8.5 4.7 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 EGF76065.1 - 1.7 8.8 13.7 52 4.1 13.7 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain FAD-oxidase_C PF02913.19 EGF76066.1 - 3.2e-59 200.6 0.0 4.4e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGF76066.1 - 1.9e-37 128.1 0.5 5.1e-37 126.7 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain LysR_substrate PF03466.20 EGF76067.1 - 6.3e-44 149.9 0.0 7.3e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EGF76067.1 - 1.5e-21 76.1 0.0 2.7e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EGF76067.1 - 0.044 13.6 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain MarR PF01047.22 EGF76067.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 MarR family Clat_adaptor_s PF01217.20 EGF76068.1 - 1.2e-46 158.2 0.1 1.3e-46 158.0 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NAM-associated PF14303.6 EGF76069.1 - 0.0069 17.1 3.4 0.49 11.1 0.2 2.1 2 0 0 2 2 2 2 No apical meristem-associated C-terminal domain tRNA_bind_3 PF17176.4 EGF76069.1 - 0.015 15.6 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 tRNA-binding domain NAGLU_C PF12972.7 EGF76069.1 - 0.015 14.8 0.5 0.022 14.3 0.5 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain RNA_polI_A34 PF08208.11 EGF76069.1 - 0.025 14.7 0.3 0.025 14.7 0.3 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-C4H2 PF10146.9 EGF76069.1 - 0.055 13.8 1.4 0.078 13.3 1.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein FapA PF03961.13 EGF76069.1 - 0.35 9.4 2.2 0.43 9.1 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Transposase_24 PF03004.14 EGF76069.1 - 3.4 7.8 7.7 7.6 6.6 0.7 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF2408 PF10303.9 EGF76069.1 - 3.5 8.2 8.0 24 5.5 8.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Asp PF00026.23 EGF76070.1 - 4.5e-08 32.9 0.2 6.1e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF742 PF05331.11 EGF76070.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) WD40 PF00400.32 EGF76071.1 - 4e-17 62.3 2.2 0.00011 22.9 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76071.1 - 3.2e-11 43.4 0.1 0.061 13.6 0.0 4.1 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF76071.1 - 0.00028 20.0 0.0 2.3 7.1 0.0 3.2 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF76071.1 - 0.00063 18.5 0.2 0.04 12.6 0.0 2.8 1 1 1 3 3 3 1 Nucleoporin Nup120/160 PH_11 PF15413.6 EGF76071.1 - 1.2 9.6 3.6 0.43 11.0 0.2 2.1 2 1 1 3 3 3 0 Pleckstrin homology domain MORN PF02493.20 EGF76072.1 - 4.4e-10 38.8 8.1 1e-05 25.1 2.8 3.7 4 0 0 4 4 4 2 MORN repeat Sen15 PF09631.10 EGF76072.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Sen15 protein DUF4246 PF14033.6 EGF76075.1 - 7.4e-30 104.5 0.0 9e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4407 PF14362.6 EGF76076.1 - 0.16 11.3 7.2 0.17 11.2 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EGF76076.1 - 1.4 8.6 10.1 1.6 8.5 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FANCAA PF15146.6 EGF76076.1 - 3.9 6.5 8.3 4.8 6.2 8.3 1.1 1 0 0 1 1 1 0 Fanconi anemia-associated Atg14 PF10186.9 EGF76076.1 - 8.6 5.3 11.8 11 5.0 11.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FTP PF07504.13 EGF76078.1 - 1.7e-05 24.5 1.3 4.2e-05 23.3 1.3 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Lyx_isomer PF07385.12 EGF76078.1 - 0.027 13.7 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 D-lyxose isomerase DUF3752 PF12572.8 EGF76079.1 - 0.0012 19.3 0.3 0.0012 19.3 0.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) YchF-GTPase_C PF06071.13 EGF76081.1 - 3.4e-37 126.5 0.2 7.3e-37 125.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGF76081.1 - 1.1e-21 77.0 0.0 4.9e-21 74.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF76081.1 - 1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF76081.1 - 0.0055 16.8 0.0 3.2 7.8 0.3 2.5 1 1 1 2 2 2 2 Dynamin family Cupin_2 PF07883.11 EGF76081.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain TGS PF02824.21 EGF76081.1 - 0.018 15.1 0.0 0.052 13.6 0.0 1.7 1 1 0 1 1 1 0 TGS domain Roc PF08477.13 EGF76081.1 - 0.074 13.3 0.0 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF5509 PF17625.2 EGF76082.1 - 0.039 13.1 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5509) Polysacc_synt_2 PF02719.15 EGF76083.1 - 4.7e-127 423.1 2.2 3e-126 420.5 0.4 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGF76083.1 - 3.9e-23 82.2 0.0 3.4e-22 79.1 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family CoA_binding_3 PF13727.6 EGF76083.1 - 3.7e-18 66.1 0.4 1.6e-17 64.1 0.1 2.1 2 0 0 2 2 2 1 CoA-binding domain RmlD_sub_bind PF04321.17 EGF76083.1 - 3.5e-15 55.9 0.1 9.6e-14 51.2 0.1 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGF76083.1 - 4e-15 56.0 0.0 3.5e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGF76083.1 - 1.9e-12 46.8 0.5 5.4e-12 45.3 0.3 1.8 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF76083.1 - 1.2e-08 34.5 0.1 6.8e-05 22.2 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein PglD_N PF17836.1 EGF76083.1 - 1.5e-06 28.7 0.1 0.00032 21.3 0.1 2.9 2 0 0 2 2 2 1 PglD N-terminal domain NAD_binding_10 PF13460.6 EGF76083.1 - 1.2e-05 25.3 1.2 0.0004 20.3 0.5 3.3 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EGF76083.1 - 0.00012 22.0 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGF76083.1 - 0.00085 18.8 0.1 0.0023 17.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Shikimate_DH PF01488.20 EGF76083.1 - 0.0016 18.5 0.0 0.52 10.4 0.0 3.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 EGF76083.1 - 0.0023 17.2 0.2 0.0087 15.3 0.2 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 EGF76083.1 - 0.003 18.4 0.1 0.01 16.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 EGF76083.1 - 0.0087 16.3 0.3 0.089 13.1 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain ThiF PF00899.21 EGF76083.1 - 0.031 13.6 0.1 1.4 8.2 0.0 2.5 2 0 0 2 2 2 0 ThiF family DAO PF01266.24 EGF76083.1 - 0.12 11.9 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Semialdhyde_dh PF01118.24 EGF76083.1 - 0.16 12.4 0.5 5.6 7.4 0.0 2.8 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DegT_DnrJ_EryC1 PF01041.17 EGF76084.1 - 1.9e-99 333.4 0.0 2.1e-99 333.3 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGF76084.1 - 0.0094 14.5 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGF76084.1 - 0.013 14.8 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AUDH_Cupin PF18637.1 EGF76084.1 - 0.021 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain Aminotran_5 PF00266.19 EGF76084.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class-V Acetyltransf_3 PF13302.7 EGF76085.1 - 1.6e-18 67.7 0.0 3.7e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGF76085.1 - 4.4e-13 49.6 0.1 9e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glycos_transf_1 PF00534.20 EGF76085.1 - 2.9e-12 46.5 0.0 5.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Acetyltransf_1 PF00583.25 EGF76085.1 - 2.2e-11 44.0 0.0 4.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_trans_1_2 PF13524.6 EGF76085.1 - 9.2e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EGF76085.1 - 4.3e-05 23.6 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Acetyltransf_10 PF13673.7 EGF76085.1 - 6e-05 23.0 0.3 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGF76085.1 - 0.00018 21.2 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_trans_1_4 PF13692.6 EGF76085.1 - 0.00018 21.9 0.0 0.00045 20.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Acetyltransf_7 PF13508.7 EGF76085.1 - 0.0038 17.6 0.1 0.0083 16.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF76085.1 - 0.008 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Glyco_transf_4 PF13439.6 EGF76085.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Polysacc_synt_2 PF02719.15 EGF76086.1 - 3.3e-105 351.4 0.1 4e-105 351.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGF76086.1 - 6.5e-25 88.0 0.0 8.1e-24 84.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_syn_2C PF08485.10 EGF76086.1 - 1.8e-22 78.8 4.4 4.1e-22 77.6 4.4 1.7 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein C-terminal 3Beta_HSD PF01073.19 EGF76086.1 - 1.7e-19 69.9 0.2 3.4e-19 68.9 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGF76086.1 - 7.2e-18 65.1 0.0 4.5e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGF76086.1 - 3.4e-12 46.6 0.0 5.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGF76086.1 - 7.3e-08 31.8 0.0 2.7e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGF76086.1 - 4.1e-07 29.4 0.1 3.5e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EGF76086.1 - 1.3e-05 24.9 0.1 2.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGF76086.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 EGF76086.1 - 0.00025 21.6 0.0 0.017 15.7 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGF76086.1 - 0.00029 20.9 0.2 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 EGF76086.1 - 0.00057 19.9 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 EGF76086.1 - 0.0052 16.8 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EGF76086.1 - 0.089 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF5300 PF17224.3 EGF76086.1 - 0.1 12.9 0.1 6 7.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5300) Epimerase PF01370.21 EGF76087.1 - 6.9e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GPI PF06560.11 EGF76087.1 - 2.3e-05 23.8 0.1 3.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 EGF76087.1 - 0.00014 21.5 0.1 0.00027 20.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain PurA PF04845.13 EGF76087.1 - 0.00064 19.1 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 PurA ssDNA and RNA-binding protein NAD_binding_4 PF07993.12 EGF76087.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Cupin_1 PF00190.22 EGF76087.1 - 0.005 16.5 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 Cupin GDP_Man_Dehyd PF16363.5 EGF76087.1 - 0.0074 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase MannoseP_isomer PF01050.18 EGF76087.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase FdtA PF05523.11 EGF76087.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal Epimerase_2 PF02350.19 EGF76088.1 - 6.4e-90 301.5 0.1 7.3e-90 301.3 0.1 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_28 PF03033.20 EGF76088.1 - 1.4e-05 25.1 0.0 0.00089 19.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain DUF2179 PF10035.9 EGF76088.1 - 0.091 12.5 0.5 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Glycos_transf_1 PF00534.20 EGF76089.1 - 2.9e-20 72.5 0.4 7.2e-20 71.2 0.2 1.7 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF76089.1 - 1.1e-16 61.5 0.0 1.9e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGF76089.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_34 PF13872.6 EGF76090.1 - 0.0035 16.3 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF2642 PF10842.8 EGF76092.1 - 0.0041 16.9 0.6 3.1 7.7 0.1 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2642) CMD PF02627.20 EGF76093.1 - 2.4e-16 59.5 0.0 3.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family OpuAC PF04069.12 EGF76094.1 - 5.4e-55 186.8 0.2 6.8e-55 186.4 0.2 1.1 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system LysR_substrate PF03466.20 EGF76095.1 - 2.6e-35 121.7 0.0 3.1e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EGF76095.1 - 0.00018 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family FliO PF04347.13 EGF76095.1 - 0.047 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO adh_short_C2 PF13561.6 EGF76096.1 - 3.8e-51 173.9 0.0 4.9e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF76096.1 - 5.8e-40 136.8 0.0 7.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF76096.1 - 2e-05 24.6 0.0 2.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 KR domain N-Term_TEN PF11474.8 EGF76096.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Acetyltransf_3 PF13302.7 EGF76097.1 - 2.6e-27 96.2 0.0 3.1e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF76097.1 - 3.2e-12 46.7 0.0 4.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EGF76097.1 - 4e-07 30.3 0.0 4.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGF76097.1 - 0.0017 18.0 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGF76097.1 - 0.005 16.8 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SBP_bac_5 PF00496.22 EGF76097.1 - 0.016 14.2 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3050 PF11251.8 EGF76097.1 - 0.058 13.0 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Acetyltransf_7 PF13508.7 EGF76097.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Transgly PF00912.22 EGF76098.1 - 2e-60 203.3 0.4 3.2e-60 202.6 0.4 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 EGF76098.1 - 2.4e-47 161.6 9.2 1e-46 159.6 9.2 2.1 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain DUF2157 PF09925.9 EGF76098.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Apt1 PF10351.9 EGF76099.1 - 0.077 11.8 11.0 0.093 11.6 11.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain N_BRCA1_IG PF16158.5 EGF76099.1 - 0.081 13.7 2.7 0.13 13.0 2.7 1.2 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene CDC45 PF02724.14 EGF76099.1 - 2.5 6.3 10.8 2.9 6.1 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGF76099.1 - 4.6 5.3 10.2 5 5.2 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family Polysacc_deac_1 PF01522.21 EGF76100.1 - 1.3e-28 99.4 0.0 1.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase UBA_6 PF18039.1 EGF76100.1 - 0.023 14.6 0.1 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain Glyco_hydro_57 PF03065.15 EGF76100.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF4317 PF14199.6 EGF76105.1 - 2.4e-93 313.3 14.1 2.7e-93 313.1 14.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4317) Metallophos PF00149.28 EGF76107.1 - 2.4e-14 54.3 4.7 3.2e-14 53.9 4.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGF76107.1 - 1.9e-07 31.4 1.3 4.3e-07 30.3 1.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L7Ae PF01248.26 EGF76107.1 - 0.092 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PP_kinase_C_1 PF17941.1 EGF76108.1 - 1.1e-74 249.5 0.1 2.6e-74 248.3 0.1 1.6 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 EGF76108.1 - 1.9e-69 232.6 0.1 1e-68 230.2 0.1 2.2 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 EGF76108.1 - 6.6e-68 228.3 3.0 1.4e-67 227.2 3.0 1.6 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PLDc_2 PF13091.6 EGF76108.1 - 2.4e-12 46.9 0.3 1.4e-06 28.2 0.1 3.0 2 1 0 2 2 2 2 PLD-like domain PP_kinase_N PF13089.6 EGF76108.1 - 2.9e-09 37.2 0.3 1e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 Polyphosphate kinase N-terminal domain Fip1 PF05182.13 EGF76108.1 - 0.058 12.9 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Fip1 motif Ppx-GppA PF02541.16 EGF76109.1 - 1.3e-55 188.8 0.0 1.8e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family MreB_Mbl PF06723.13 EGF76109.1 - 0.0089 14.9 0.1 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein IFN-gamma PF00714.17 EGF76109.1 - 0.011 15.5 0.2 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Interferon gamma sCache_like PF16736.5 EGF76109.1 - 0.027 14.5 1.3 0.079 13.0 1.3 1.8 1 0 0 1 1 1 0 Single Cache-like FtsA PF14450.6 EGF76109.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Cell division protein FtsA Arrestin_C PF02752.22 EGF76110.1 - 2.2e-12 47.6 1.4 4e-09 37.0 0.5 3.4 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGF76110.1 - 5.1e-08 33.1 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ArfGap PF01412.18 EGF76111.1 - 3.8e-33 114.0 0.0 8.7e-33 112.9 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Evr1_Alr PF04777.13 EGF76112.1 - 2.8e-30 104.7 1.3 3.7e-30 104.4 1.3 1.1 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC4 PF18775.1 EGF76112.1 - 0.29 11.3 1.9 0.35 11.1 1.0 1.6 1 1 1 2 2 2 0 APOBEC4 Mss4 PF04421.13 EGF76113.1 - 3.1e-15 56.1 0.0 5.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein LysR_substrate PF03466.20 EGF76114.1 - 2e-33 115.5 0.0 2.4e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EGF76114.1 - 9.7e-18 63.9 0.0 1.8e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_3 PF01381.22 EGF76114.1 - 0.048 13.7 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_30 PF13556.6 EGF76114.1 - 0.048 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Acetyltransf_19 PF18015.1 EGF76115.1 - 0.18 12.0 1.4 11 6.3 0.0 2.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain TPR_19 PF14559.6 EGF76115.1 - 0.39 11.3 1.9 2.1 8.9 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2220 PF09983.9 EGF76116.1 - 4.2e-10 39.3 0.2 1.2e-09 37.8 0.2 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DnaB_C PF03796.15 EGF76117.1 - 1.3e-62 211.5 3.4 4.2e-42 144.2 1.1 2.3 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain AAA_25 PF13481.6 EGF76117.1 - 1.4e-06 28.0 0.0 5.5e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain DnaB PF00772.21 EGF76117.1 - 1.8e-06 28.0 0.0 5.6e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain ATPase PF06745.13 EGF76117.1 - 0.00066 19.1 0.0 0.0013 18.1 0.0 1.6 1 1 0 1 1 1 1 KaiC KTI12 PF08433.10 EGF76117.1 - 0.0034 16.9 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 EGF76117.1 - 0.048 13.9 0.6 0.18 12.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGF76117.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Imm8 PF15586.6 EGF76117.1 - 0.13 12.3 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 8 FliG_N PF14842.6 EGF76118.1 - 0.013 16.0 2.5 0.43 11.1 0.4 2.1 2 0 0 2 2 2 0 FliG N-terminal domain DnaB_2 PF07261.11 EGF76119.1 - 3.9e-12 45.8 1.1 6e-12 45.1 1.1 1.3 1 0 0 1 1 1 1 Replication initiation and membrane attachment adh_short_C2 PF13561.6 EGF76120.1 - 2.5e-56 190.9 2.0 3.5e-56 190.4 2.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF76120.1 - 1.1e-55 188.2 1.4 1.4e-55 187.8 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF76120.1 - 0.00017 21.6 0.6 0.0005 20.0 0.6 1.8 1 1 0 1 1 1 1 KR domain RuBisCO_large PF00016.20 EGF76120.1 - 0.042 13.1 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Epimerase PF01370.21 EGF76120.1 - 0.12 11.8 0.3 0.3 10.5 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lipocalin_5 PF13924.6 EGF76121.1 - 4e-20 72.1 0.0 4.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain DUF4246 PF14033.6 EGF76122.1 - 2.6e-58 198.3 0.0 4e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RP-C_C PF11800.8 EGF76123.1 - 0.025 14.7 3.2 0.058 13.5 3.2 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region WD40_4 PF16300.5 EGF76126.1 - 2.3e-31 107.4 0.7 2.4e-14 53.0 0.1 2.8 3 0 0 3 3 3 2 Type of WD40 repeat DUF1899 PF08953.11 EGF76126.1 - 3.8e-08 33.1 0.0 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EGF76126.1 - 0.00091 20.0 0.1 2.5 9.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76126.1 - 0.0015 18.8 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Trypsin_2 PF13365.6 EGF76128.1 - 0.00013 22.9 0.1 0.00023 22.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain CCDC106 PF15794.5 EGF76128.1 - 0.0081 15.9 6.6 0.011 15.5 6.6 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 DUF1090 PF06476.12 EGF76128.1 - 0.013 15.6 5.5 0.02 15.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) FliJ PF02050.16 EGF76128.1 - 0.086 13.1 4.2 0.17 12.1 4.2 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Phage_GP20 PF06810.11 EGF76128.1 - 0.2 11.4 5.5 0.41 10.4 5.5 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF737 PF05300.11 EGF76128.1 - 0.22 11.8 5.9 0.35 11.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) V_ATPase_I PF01496.19 EGF76128.1 - 0.36 8.7 1.9 0.4 8.5 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Trypsin PF00089.26 EGF76128.1 - 0.64 9.8 3.1 1.2 8.9 3.0 1.6 1 1 0 1 1 1 0 Trypsin OmpH PF03938.14 EGF76128.1 - 1.5 9.1 8.2 2.1 8.7 8.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) WD40_4 PF16300.5 EGF76129.1 - 1.3e-14 53.8 0.1 3.5e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Type of WD40 repeat DUF1899 PF08953.11 EGF76129.1 - 5.3e-08 32.6 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 EGF76129.1 - 3.8e-07 30.3 0.1 0.19 12.0 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF76129.1 - 0.00018 22.2 2.2 3.6 8.6 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.20 EGF76130.1 - 1.7e-65 221.0 0.0 4.5e-65 219.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGF76130.1 - 0.17 11.0 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Calreticulin PF00262.18 EGF76131.1 - 8.6e-161 534.8 5.5 1.2e-160 534.4 5.5 1.2 1 0 0 1 1 1 1 Calreticulin family FAM176 PF14851.6 EGF76131.1 - 0.021 14.5 0.8 0.044 13.4 0.8 1.5 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 EGF76131.1 - 0.034 13.9 0.3 0.054 13.2 0.3 1.3 1 0 0 1 1 1 0 Connexin FHIPEP PF00771.20 EGF76131.1 - 0.049 12.1 0.1 0.071 11.6 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family Conotoxin PF02950.17 EGF76131.1 - 0.12 13.5 0.0 0.26 12.4 0.0 1.5 1 0 0 1 1 1 0 Conotoxin Folate_carrier PF01770.18 EGF76131.1 - 0.23 10.1 0.2 0.32 9.7 0.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier TRAP_alpha PF03896.16 EGF76131.1 - 0.27 10.4 2.7 0.48 9.6 2.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit G0-G1_switch_2 PF15103.6 EGF76131.1 - 1.3 9.5 4.7 0.2 12.1 0.9 1.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 Adeno_terminal PF02459.15 EGF76131.1 - 1.3 7.3 4.4 1.9 6.8 4.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein IlvC PF01450.19 EGF76132.1 - 0.05 13.9 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain RPN1_C PF18051.1 EGF76133.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal TetR_N PF00440.23 EGF76134.1 - 1.8e-13 50.1 0.1 4e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Glyoxalase PF00903.25 EGF76134.1 - 1.3e-06 28.6 0.0 3.5e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGF76134.1 - 0.0032 17.4 2.0 0.061 13.3 0.1 2.6 2 0 0 2 2 2 1 Glyoxalase-like domain HTH_40 PF14493.6 EGF76134.1 - 0.042 14.3 2.2 0.25 11.8 0.1 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain LytR_cpsA_psr PF03816.14 EGF76134.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain DHHA1 PF02272.19 EGF76134.1 - 0.14 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 DHHA1 domain ASCH PF04266.14 EGF76135.1 - 0.002 18.7 0.2 0.0061 17.1 0.2 1.7 1 1 0 1 1 1 1 ASCH domain PepSY PF03413.19 EGF76136.1 - 1.6e-24 86.2 10.7 4.5e-12 46.3 2.2 2.4 2 0 0 2 2 2 2 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 EGF76136.1 - 3.1e-07 30.3 17.2 0.0042 17.1 2.6 3.3 2 1 0 2 2 2 2 Peptidase propeptide and YPEB domain DUF2369 PF10179.9 EGF76136.1 - 6.3e-05 23.3 1.4 0.26 11.7 0.1 2.7 2 2 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) FlgD_ig PF13860.6 EGF76136.1 - 0.0054 16.6 10.7 0.16 11.9 1.6 2.8 2 1 0 2 2 2 2 FlgD Ig-like domain Big_10 PF17964.1 EGF76136.1 - 0.0062 16.5 17.3 0.59 10.1 1.6 4.1 1 1 3 4 4 4 2 Bacterial Ig domain TonB_C PF03544.14 EGF76136.1 - 0.011 16.2 3.3 1.2 9.7 0.3 2.5 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal UPF0158 PF03682.13 EGF76136.1 - 0.036 14.1 6.9 0.28 11.2 0.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) DUF4833 PF16117.5 EGF76136.1 - 0.041 13.9 0.1 1.8 8.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4833) PilA4 PF18682.1 EGF76136.1 - 0.11 12.9 2.9 9.1 6.7 0.2 2.4 2 0 0 2 2 2 0 Pilin A4 NADH_Oxid_Nqo15 PF11497.8 EGF76136.1 - 0.16 12.0 0.0 14 5.8 0.0 2.6 2 1 1 3 3 3 0 NADH-quinone oxidoreductase chain 15 Mucin_bdg PF03272.13 EGF76136.1 - 0.16 12.0 4.4 4.5 7.3 0.5 2.3 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module DUF4292 PF14125.6 EGF76136.1 - 0.16 11.6 2.3 5.6 6.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4292) PRC PF05239.16 EGF76136.1 - 1 9.5 14.7 15 5.8 0.3 4.2 2 2 2 4 4 4 0 PRC-barrel domain Gmad2 PF10648.9 EGF76136.1 - 1.3 9.3 8.6 8.6 6.7 0.1 3.4 3 1 0 3 3 2 0 Immunoglobulin-like domain of bacterial spore germination Tudor_RapA PF18337.1 EGF76136.1 - 1.4 9.1 6.9 3 8.1 0.5 3.3 2 2 1 3 3 3 0 RapA N-terminal Tudor like domain SMN PF06003.12 EGF76136.1 - 5.2 6.2 6.1 2 7.6 2.9 1.7 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) SWM_repeat PF13753.6 EGF76136.1 - 9 6.5 10.0 2.6 8.2 1.0 3.1 2 2 2 4 4 4 0 Putative flagellar system-associated repeat HATPase_c PF02518.26 EGF76137.1 - 4.7e-25 88.3 0.8 9.4e-25 87.3 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ArlS_N PF18719.1 EGF76137.1 - 8e-21 74.6 5.3 8e-21 74.6 5.3 2.8 2 1 0 3 3 3 1 ArlS sensor domain HisKA PF00512.25 EGF76137.1 - 7.3e-15 54.8 1.5 1.5e-14 53.8 0.5 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EGF76137.1 - 1.5e-10 41.3 0.0 3.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 EGF76137.1 - 2e-07 30.9 0.5 5.2e-07 29.6 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EGF76137.1 - 0.00011 22.0 0.4 0.00011 22.0 0.4 3.1 4 1 0 4 4 4 1 GHKL domain DUF4064 PF13273.6 EGF76137.1 - 0.0079 16.5 1.3 0.32 11.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) SNARE PF05739.19 EGF76137.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.5 2 0 0 2 2 2 0 SNARE domain Mqo PF06039.15 EGF76138.1 - 4.6e-234 777.4 0.0 5.2e-234 777.3 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 EGF76138.1 - 0.0047 15.7 0.0 0.011 14.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein DUF364 PF04016.12 EGF76138.1 - 0.016 14.8 0.0 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative heavy-metal chelation Pyr_redox_2 PF07992.14 EGF76138.1 - 0.054 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGF76138.1 - 0.071 12.2 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PepSY_2 PF13670.6 EGF76138.1 - 0.14 12.2 0.2 0.38 10.8 0.2 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2914 PF11141.8 EGF76138.1 - 0.14 11.9 0.1 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) Pyr_redox PF00070.27 EGF76138.1 - 0.16 12.6 0.0 1.8 9.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1963 PF09234.10 EGF76139.1 - 8.7e-67 225.7 1.4 1e-66 225.5 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) MFS_1 PF07690.16 EGF76140.1 - 1.2e-39 136.3 50.2 4.9e-18 65.2 12.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF76140.1 - 0.00035 19.6 12.4 0.00035 19.6 12.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 EGF76140.1 - 0.071 11.5 12.4 0.13 10.6 12.0 1.8 1 1 0 1 1 1 0 Transmembrane secretion effector Cation_efflux PF01545.21 EGF76142.1 - 9.5e-10 38.5 0.1 1.1e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGF76142.1 - 2.7e-05 24.2 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter cobW PF02492.19 EGF76143.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_CTD PF16326.5 EGF76144.1 - 0.062 13.6 0.2 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain TMPIT PF07851.13 EGF76144.1 - 0.12 11.6 0.3 0.16 11.2 0.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Uso1_p115_C PF04871.13 EGF76144.1 - 0.17 12.3 0.8 0.9 9.9 0.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tup_N PF08581.10 EGF76145.1 - 0.33 11.3 3.3 0.37 11.1 0.9 2.0 1 1 1 2 2 2 0 Tup N-terminal Med21 PF11221.8 EGF76145.1 - 1.7 8.9 5.3 4.2 7.6 5.3 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex NMT1 PF09084.11 EGF76146.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like CCDC106 PF15794.5 EGF76150.1 - 0.00066 19.5 9.6 0.00066 19.5 9.6 1.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 CCDC53 PF10152.9 EGF76150.1 - 0.14 12.5 5.6 9.8 6.6 3.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex GEMIN8 PF15348.6 EGF76150.1 - 0.86 9.9 10.4 0.12 12.6 6.7 1.5 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 RP-C_C PF11800.8 EGF76150.1 - 6.5 6.8 9.6 0.55 10.3 5.1 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Asp PF00026.23 EGF76151.1 - 1.6e-12 47.5 0.3 5.3e-12 45.8 0.3 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76151.1 - 0.0011 18.8 0.0 0.0088 15.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF742 PF05331.11 EGF76151.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Rsbr_N PF08678.10 EGF76152.1 - 0.0086 16.2 0.6 0.029 14.5 0.2 2.0 1 1 1 2 2 2 1 Rsbr N terminal PA26 PF04636.13 EGF76152.1 - 0.025 13.5 0.6 0.028 13.3 0.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PI3K_P85_iSH2 PF16454.5 EGF76152.1 - 0.04 13.5 6.6 0.092 12.3 6.6 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LAMTOR PF15454.6 EGF76152.1 - 0.2 12.3 6.0 3.2 8.4 0.2 2.8 1 1 2 3 3 3 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Uteroglobin PF01099.17 EGF76152.1 - 0.3 11.5 3.5 16 5.9 0.0 2.7 3 0 0 3 3 3 0 Uteroglobin family DUF4246 PF14033.6 EGF76153.1 - 1.9e-29 103.1 0.1 2.7e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Sigma70_ner PF04546.13 EGF76155.1 - 0.011 15.6 0.9 0.016 15.1 0.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cytochrom_B562 PF07361.11 EGF76155.1 - 0.15 12.7 3.1 0.15 12.7 0.4 2.1 2 0 0 2 2 2 0 Cytochrome b562 DUF4558 PF15104.6 EGF76155.1 - 4.1 7.5 8.6 0.21 11.7 1.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4558) MogR_DNAbind PF12181.8 EGF76156.1 - 0.011 15.6 3.0 0.15 12.0 1.0 2.1 2 0 0 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) TnpV PF14198.6 EGF76156.1 - 0.02 14.9 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Transposon-encoded protein TnpV FTA4 PF13093.6 EGF76156.1 - 0.027 14.4 0.1 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SR-25 PF10500.9 EGF76156.1 - 0.077 12.6 3.9 0.11 12.1 3.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ly49 PF08391.10 EGF76157.1 - 0.00018 21.8 0.1 0.00032 21.0 0.1 1.3 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region PAH PF02671.21 EGF76157.1 - 0.017 15.2 0.2 0.052 13.7 0.0 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat Com_YlbF PF06133.11 EGF76157.1 - 0.15 12.7 1.8 0.59 10.8 1.7 1.8 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA PSP1 PF04468.12 EGF76158.1 - 0.027 14.7 0.0 0.029 14.6 0.0 1.1 1 0 0 1 1 1 0 PSP1 C-terminal conserved region PI31_Prot_N PF11566.8 EGF76159.1 - 2.2e-35 121.9 0.1 2.8e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGF76159.1 - 1.1e-14 55.4 16.2 1.1e-14 55.4 16.2 2.2 3 0 0 3 3 3 1 PI31 proteasome regulator Dynamitin PF04912.14 EGF76160.1 - 0.017 14.5 0.3 0.022 14.1 0.3 1.1 1 0 0 1 1 1 0 Dynamitin RMI1_C PF16099.5 EGF76160.1 - 0.056 13.3 0.1 0.88 9.4 0.0 2.0 2 0 0 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold CC2-LZ PF16516.5 EGF76160.1 - 0.081 13.3 2.4 0.21 12.0 0.5 2.0 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator WaaY PF06176.11 EGF76161.1 - 0.00038 20.1 0.3 1 8.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide core biosynthesis protein (WaaY) fragilysinNterm PF16376.5 EGF76161.1 - 0.005 16.6 1.7 3.3 7.4 0.1 3.0 2 2 0 2 2 2 2 N-terminal domain of fragilysin Peptidase_C57 PF03290.13 EGF76161.1 - 0.01 14.6 0.0 3.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase DUF4011 PF13195.6 EGF76161.1 - 0.025 14.5 0.0 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) BiPBP_C PF06832.12 EGF76161.1 - 0.04 14.0 0.0 23 5.1 0.0 3.2 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family DUF4590 PF15257.6 EGF76161.1 - 0.064 13.2 1.7 9.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4590) FlbT PF07378.11 EGF76161.1 - 0.078 13.1 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FlbT DUF4702 PF15774.5 EGF76161.1 - 0.13 11.2 0.0 16 4.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4702) MxiM PF11441.8 EGF76161.1 - 0.13 12.5 7.6 2.3 8.6 0.1 3.2 4 0 0 4 4 4 0 Pilot protein MxiM CS PF04969.16 EGF76161.1 - 0.39 11.8 2.7 37 5.4 0.2 3.0 2 0 0 2 2 2 0 CS domain Peptidase_S41 PF03572.18 EGF76162.1 - 6.9e-12 45.2 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PPR_1 PF12854.7 EGF76162.1 - 0.23 11.2 0.4 0.43 10.3 0.4 1.4 1 0 0 1 1 1 0 PPR repeat Abhydrolase_1 PF00561.20 EGF76163.1 - 6.7e-24 84.9 0.0 9.3e-20 71.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF76163.1 - 2.3e-16 61.1 0.4 4.6e-16 60.1 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF76163.1 - 5.8e-13 48.7 0.0 1e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGF76163.1 - 1.6e-05 24.9 0.0 3.7e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EGF76163.1 - 5.4e-05 23.0 0.0 9.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 EGF76163.1 - 0.00026 19.8 0.0 0.00045 19.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 EGF76163.1 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 EGF76163.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 EGF76163.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 EGF76163.1 - 0.019 13.9 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EGF76163.1 - 0.026 14.3 0.0 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGF76163.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family VASt PF16016.5 EGF76164.1 - 6.5e-20 72.1 0.4 2e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain Sod_Fe_C PF02777.18 EGF76165.1 - 1.4e-33 115.1 0.4 2.5e-33 114.3 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGF76165.1 - 7.8e-24 84.0 0.4 1.9e-23 82.7 0.4 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain 2OG-FeII_Oxy_2 PF13532.6 EGF76166.1 - 2.7e-11 44.0 0.0 7e-11 42.7 0.0 1.5 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 EGF76167.1 - 0.0025 18.6 9.7 0.067 14.1 0.6 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PdaC PF13739.6 EGF76169.1 - 0.08 13.9 2.4 14 6.7 0.4 2.7 2 1 0 2 2 2 0 Deacetylase PdaC CKAP2_C PF15297.6 EGF76169.1 - 0.22 10.6 0.1 0.34 9.9 0.1 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Sigma70_ner PF04546.13 EGF76169.1 - 4.1 7.2 4.7 14 5.5 0.0 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region Sod_Fe_C PF02777.18 EGF76170.1 - 1.3e-32 111.9 0.4 2.3e-32 111.2 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGF76170.1 - 8.4e-24 83.9 0.4 1.9e-23 82.7 0.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain 2OG-FeII_Oxy_2 PF13532.6 EGF76171.1 - 1.1e-11 45.3 0.0 3e-11 43.9 0.0 1.6 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EGF76172.1 - 4.3e-41 141.0 0.0 3.4e-25 88.9 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76172.1 - 1.9e-19 70.0 0.0 8.8e-11 41.6 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase NAD_binding_9 PF13454.6 EGF76172.1 - 0.16 11.9 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pox_A_type_inc PF04508.12 EGF76172.1 - 0.17 11.7 1.6 0.6 10.1 1.6 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Aa_trans PF01490.18 EGF76173.1 - 1.4e-09 37.2 2.2 2e-09 36.7 2.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGF76173.1 - 0.029 13.4 1.9 0.042 12.9 1.9 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family GTP-bdg_M PF16360.5 EGF76174.1 - 0.32 11.6 0.2 0.32 11.6 0.2 2.3 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region Ndc1_Nup PF09531.10 EGF76174.1 - 1.6 7.3 8.2 2.1 7.0 8.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 EGF76174.1 - 2.2 6.3 7.0 2.7 6.0 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3368 PF11848.8 EGF76175.1 - 0.075 12.8 0.4 0.37 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) DUF2811 PF10929.8 EGF76175.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) SlyX PF04102.12 EGF76175.1 - 0.14 12.8 0.6 1.9 9.2 0.2 2.2 1 1 0 2 2 2 0 SlyX HR1 PF02185.16 EGF76175.1 - 1.4 9.1 4.9 22 5.3 4.9 2.2 1 1 0 1 1 1 0 Hr1 repeat WH2 PF02205.20 EGF76176.1 - 2.8e-07 30.1 0.0 8.9e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 WH2 motif AKNA PF12443.8 EGF76176.1 - 2.9e-05 24.7 0.1 1.8 9.3 0.0 4.7 5 0 0 5 5 5 3 AT-hook-containing transcription factor DUF2315 PF10231.9 EGF76177.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Apoptogenic protein 1 Alk_phosphatase PF00245.20 EGF76178.1 - 4.2e-47 161.0 1.0 4.7e-47 160.9 1.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGF76178.1 - 4.6e-07 29.4 0.9 2.1e-06 27.3 0.9 1.9 1 1 0 1 1 1 1 Metalloenzyme superfamily FAD_binding_4 PF01565.23 EGF76178.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Bac_luciferase PF00296.20 EGF76179.1 - 5.2e-27 95.1 0.3 8.3e-27 94.4 0.3 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Elong-fact-P_C PF09285.11 EGF76179.1 - 0.086 12.6 0.4 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor P, C-terminal Molybdopterin PF00384.22 EGF76180.1 - 8.3e-40 137.0 0.0 1.2e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase FdhD-NarQ PF02634.15 EGF76180.1 - 7.3e-38 130.6 0.1 1.4e-37 129.7 0.1 1.4 1 0 0 1 1 1 1 FdhD/NarQ family Mob_synth_C PF06463.13 EGF76180.1 - 8.8e-38 129.1 0.2 2.2e-37 127.8 0.0 1.9 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C MFS_1 PF07690.16 EGF76180.1 - 1.8e-32 112.7 31.3 2.5e-32 112.2 31.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Radical_SAM PF04055.21 EGF76180.1 - 3.4e-31 108.9 0.0 8.8e-31 107.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Molydop_binding PF01568.21 EGF76180.1 - 1.5e-09 37.9 0.0 9.6e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Fer4_12 PF13353.6 EGF76180.1 - 4.6e-09 36.7 0.0 1.8e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGF76180.1 - 2e-06 27.9 0.0 7.8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Sugar_tr PF00083.24 EGF76180.1 - 0.0021 17.0 26.7 0.0033 16.4 1.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter ThiF PF00899.21 EGF76181.1 - 3.1e-53 180.6 0.0 4e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGF76181.1 - 2.2e-05 24.6 0.8 0.00018 21.6 0.1 2.5 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGF76181.1 - 4.7e-05 23.8 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EGF76181.1 - 0.0011 19.3 0.6 0.01 16.1 0.4 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGF76181.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MoeA_N PF03453.17 EGF76182.1 - 7.6e-35 120.0 0.0 9.4e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) DUF4037 PF13228.6 EGF76182.1 - 0.0074 17.1 0.0 0.011 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4037) MoaE PF02391.17 EGF76183.1 - 5.5e-36 123.3 0.4 6.8e-36 123.0 0.4 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 EGF76184.1 - 5.9e-16 58.9 0.1 6.5e-16 58.7 0.1 1.0 1 0 0 1 1 1 1 ThiS family SBP_bac_11 PF13531.6 EGF76185.1 - 5.4e-49 167.0 0.1 6.1e-49 166.8 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EGF76185.1 - 3.9e-18 66.4 2.9 2.6e-16 60.5 2.9 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 EGF76185.1 - 9e-06 25.6 1.1 0.0035 17.0 0.0 2.1 1 1 1 2 2 2 2 PBP superfamily domain BPD_transp_1 PF00528.22 EGF76186.1 - 1.9e-17 63.6 12.3 2e-17 63.5 12.3 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Pirin PF02678.16 EGF76187.1 - 1.7e-12 47.2 0.1 9.9e-12 44.8 0.1 2.0 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 EGF76187.1 - 0.0002 21.5 0.0 0.00033 20.8 0.0 1.3 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain GerA PF03323.13 EGF76188.1 - 4.7e-162 539.7 5.7 5.2e-162 539.5 5.7 1.0 1 0 0 1 1 1 1 Bacillus/Clostridium GerA spore germination protein Spore_permease PF03845.13 EGF76189.1 - 2.2e-63 214.0 34.9 2.2e-63 214.0 34.9 1.6 1 1 0 1 1 1 1 Spore germination protein ADH_N PF08240.12 EGF76190.1 - 5.7e-26 90.5 1.3 3.6e-25 88.0 1.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGF76190.1 - 2.2e-10 40.6 0.9 1.8e-09 37.7 0.1 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGF76190.1 - 9.1e-08 31.7 0.7 2.1e-07 30.5 0.3 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 EGF76190.1 - 0.0016 17.9 0.2 0.0032 16.9 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme FAD_binding_2 PF00890.24 EGF76190.1 - 0.0026 16.9 0.2 0.0036 16.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EGF76190.1 - 0.012 14.9 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EGF76190.1 - 0.038 13.2 4.7 1.1 8.4 0.8 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF76190.1 - 0.041 13.2 2.5 0.07 12.5 2.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EGF76190.1 - 0.052 12.9 0.1 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EGF76190.1 - 0.084 12.1 0.5 0.15 11.3 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MoaC PF01967.21 EGF76191.1 - 3.7e-54 182.5 2.5 4.2e-54 182.3 2.5 1.0 1 0 0 1 1 1 1 MoaC family DUF2258 PF10015.9 EGF76191.1 - 0.00068 19.7 0.5 0.0012 18.9 0.5 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2258) GAPT PF11770.8 EGF76191.1 - 0.06 13.2 0.3 0.39 10.6 0.3 2.1 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Aldo_ket_red PF00248.21 EGF76192.1 - 1.5e-54 185.2 0.3 1.7e-54 185.0 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short_C2 PF13561.6 EGF76193.1 - 1.3e-67 227.8 0.4 1.5e-67 227.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF76193.1 - 2e-57 193.8 1.7 2.5e-57 193.5 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF76193.1 - 1.4e-08 34.9 0.6 2.9e-08 33.8 0.5 1.6 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EGF76193.1 - 0.024 14.7 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AraC_N PF06719.13 EGF76194.1 - 3.2e-38 130.7 0.1 5.5e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 EGF76194.1 - 1.1e-19 70.5 0.5 2.5e-19 69.3 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EGF76194.1 - 5.7e-11 42.2 0.4 5e-06 26.5 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cys_Met_Meta_PP PF01053.20 EGF76195.1 - 2.3e-141 470.8 0.0 2.6e-141 470.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGF76195.1 - 1.5e-11 44.3 0.1 2.5e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGF76195.1 - 2.7e-08 33.4 0.0 3.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGF76195.1 - 3.7e-06 26.1 0.1 6.6e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EGF76195.1 - 9.9e-05 21.0 0.0 0.00018 20.2 0.0 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase CMD PF02627.20 EGF76196.1 - 1.3e-42 143.7 1.9 5.4e-21 74.5 0.2 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Thioredoxin_2 PF13098.6 EGF76196.1 - 0.00024 21.5 0.1 0.75 10.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain DUF4253 PF14062.6 EGF76196.1 - 0.00054 20.1 0.1 1 9.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4253) Redoxin PF08534.10 EGF76196.1 - 0.0025 17.5 0.1 0.96 9.2 0.0 2.2 2 0 0 2 2 2 2 Redoxin zf-RING_9 PF13901.6 EGF76196.1 - 0.0044 17.0 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon DUF5371 PF17341.2 EGF76196.1 - 0.0055 16.9 1.0 3.5 7.9 0.2 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5371) Ser_hydrolase PF06821.13 EGF76196.1 - 0.021 14.7 2.6 3.6 7.4 0.5 2.1 2 0 0 2 2 2 0 Serine hydrolase NhaB PF06450.12 EGF76196.1 - 0.12 11.2 0.0 2.3 7.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial Na+/H+ antiporter B (NhaB) SGTA_dimer PF16546.5 EGF76196.1 - 0.3 10.9 3.4 2.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Homodimerisation domain of SGTA Glutaredoxin PF00462.24 EGF76196.1 - 0.37 11.0 2.0 26 5.1 0.2 2.6 2 0 0 2 2 2 0 Glutaredoxin Thiolase_N PF00108.23 EGF76197.1 - 8.9e-74 248.1 0.1 4.5e-73 245.8 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF76197.1 - 2.3e-44 150.0 0.3 4.2e-44 149.2 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGF76197.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain SSF PF00474.17 EGF76198.1 - 7.9e-42 143.5 27.7 4.1e-40 137.9 21.3 2.1 1 1 1 2 2 2 2 Sodium:solute symporter family AMP-binding PF00501.28 EGF76199.1 - 1.4e-44 152.4 0.0 1.9e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF76199.1 - 3.9e-09 37.3 0.1 1.1e-08 35.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGF76199.1 - 8.1e-08 32.1 1.1 1.8e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus TK PF00265.18 EGF76199.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Pyr_redox_2 PF07992.14 EGF76200.1 - 4.7e-34 118.0 0.0 7.3e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sigma70_r4_2 PF08281.12 EGF76200.1 - 4.4e-10 39.1 1.2 9.7e-10 38.0 0.3 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EGF76200.1 - 8.4e-08 31.9 0.1 1.7e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Pyr_redox PF00070.27 EGF76200.1 - 0.0016 18.9 0.4 0.06 13.9 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGF76200.1 - 0.0055 16.7 1.2 4.5 7.2 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Sigma70_r4 PF04545.16 EGF76200.1 - 0.026 14.1 0.1 0.057 12.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 SnoaL_2 PF12680.7 EGF76200.1 - 0.059 14.0 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain NAD_binding_10 PF13460.6 EGF76201.1 - 4.1e-18 65.9 0.0 6.5e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGF76201.1 - 3.5e-07 30.0 0.2 1.1e-06 28.4 0.3 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EGF76201.1 - 0.00029 20.4 0.1 0.00041 19.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGF76201.1 - 0.014 15.7 0.2 0.023 15.0 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EGF76201.1 - 0.024 14.8 0.3 0.041 14.0 0.3 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PALP PF00291.25 EGF76201.1 - 0.03 13.7 0.1 0.034 13.6 0.1 1.3 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GDP_Man_Dehyd PF16363.5 EGF76201.1 - 0.036 13.5 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGF76201.1 - 0.036 13.2 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EGF76201.1 - 0.14 12.6 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Atu4866 PF11512.8 EGF76202.1 - 4.7e-40 135.8 2.1 7.6e-40 135.2 2.1 1.3 1 0 0 1 1 1 1 Agrobacterium tumefaciens protein Atu4866 Meth_synt_2 PF01717.18 EGF76203.1 - 1.6e-21 77.0 0.0 1.9e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain URO-D PF01208.17 EGF76203.1 - 0.00054 19.2 0.0 0.00098 18.4 0.0 1.4 1 1 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Meth_synt_1 PF08267.12 EGF76203.1 - 0.019 14.5 0.1 1.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain ChaB PF06150.12 EGF76204.1 - 2.2e-21 76.2 2.5 2.5e-21 76.0 2.5 1.1 1 0 0 1 1 1 1 ChaB Tricorn_C1 PF14684.6 EGF76204.1 - 0.077 13.1 0.3 0.088 12.9 0.3 1.2 1 0 0 1 1 1 0 Tricorn protease C1 domain Spore_III_AB PF09548.10 EGF76204.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PGDH_C PF16896.5 EGF76205.1 - 0.025 14.5 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphogluconate dehydrogenase (decarboxylating) C-term DUF1657 PF07870.11 EGF76205.1 - 0.028 14.3 0.3 4.4 7.3 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) Alpha-mann_mid PF09261.11 EGF76205.1 - 0.065 13.4 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Alpha mannosidase middle domain EZH2_WD-Binding PF11616.8 EGF76205.1 - 0.068 13.3 1.2 16 5.7 0.1 2.6 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Get5_bdg PF16843.5 EGF76205.1 - 0.14 11.7 1.2 1.1 8.9 0.0 2.9 4 1 1 5 5 5 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Asp PF00026.23 EGF76206.1 - 9.6e-13 48.2 0.0 2.4e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76206.1 - 4.3e-05 23.3 0.1 0.00014 21.6 0.1 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DnaJ-X PF14308.6 EGF76207.1 - 2.4e-31 108.9 2.2 9.3e-30 103.6 2.2 2.3 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF76207.1 - 2.5e-23 81.9 1.0 7e-23 80.5 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain ING PF12998.7 EGF76207.1 - 0.082 13.5 0.3 0.46 11.1 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SMAP PF15477.6 EGF76207.1 - 0.29 12.1 2.9 0.42 11.6 0.2 2.5 3 0 0 3 3 3 0 Small acidic protein family MetOD2 PF18548.1 EGF76208.1 - 0.041 14.0 1.2 0.13 12.4 1.0 2.0 1 1 0 1 1 1 0 Metanogen output domain 2 TMF_DNA_bd PF12329.8 EGF76208.1 - 1.7 8.7 6.2 0.65 10.0 0.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CNDH2_M PF16869.5 EGF76210.1 - 0.014 16.1 2.0 0.014 16.1 2.0 2.5 2 1 1 3 3 3 0 PF16858 Terminase_4 PF05119.12 EGF76210.1 - 0.031 14.7 0.6 0.11 12.9 0.8 1.8 2 0 0 2 2 2 0 Phage terminase, small subunit FapA PF03961.13 EGF76210.1 - 1.3 7.5 4.1 1.7 7.2 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cmyb_C PF09316.10 EGF76211.1 - 0.041 13.6 0.4 0.041 13.6 0.4 2.2 2 2 0 2 2 2 0 C-myb, C-terminal DUF2201_N PF13203.6 EGF76211.1 - 3.8 7.0 7.4 6.2 6.3 7.1 1.7 1 1 1 2 2 2 0 Putative metallopeptidase domain SPOUT_MTase PF02590.17 EGF76213.1 - 3.4e-59 199.3 1.9 3.7e-59 199.1 1.9 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase DoxX_2 PF13564.6 EGF76214.1 - 9.5e-23 80.3 6.0 1.3e-22 79.9 6.0 1.2 1 0 0 1 1 1 1 DoxX-like family MARVEL PF01284.23 EGF76214.1 - 0.025 14.6 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Membrane-associating domain GAPT PF11770.8 EGF76214.1 - 0.052 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Peptidase_U4 PF03419.13 EGF76214.1 - 0.15 11.3 3.3 0.22 10.8 3.3 1.3 1 1 0 1 1 1 0 Sporulation factor SpoIIGA YrhC PF14143.6 EGF76214.1 - 0.29 11.3 2.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 YrhC-like protein DoxX PF07681.12 EGF76214.1 - 0.76 10.4 11.9 0.064 13.8 6.5 2.0 2 1 0 2 2 2 0 DoxX Peptidase_M20 PF01546.28 EGF76215.1 - 2e-36 125.7 0.1 2.5e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGF76215.1 - 1.4e-21 76.4 0.0 2.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGF76215.1 - 0.00018 21.2 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGF76215.1 - 0.0035 16.4 0.1 0.071 12.1 0.1 2.7 2 1 1 3 3 3 1 M42 glutamyl aminopeptidase Acyltransf_C PF16076.5 EGF76215.1 - 0.08 13.1 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Acyltransferase C-terminus Glyco_hydro_3_C PF01915.22 EGF76216.1 - 3.1e-43 148.1 0.0 6.9e-43 147.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGF76216.1 - 3e-42 145.1 0.0 5.1e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGF76216.1 - 2.1e-16 59.8 0.0 4.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF2381 PF09544.10 EGF76216.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Beta_helix PF13229.6 EGF76217.1 - 3.7e-12 46.4 12.0 4.4e-11 42.9 11.3 2.3 1 1 0 1 1 1 1 Right handed beta helix region DUF1565 PF07602.11 EGF76217.1 - 4.7e-10 39.2 2.3 7.3e-10 38.6 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1565) NosD PF05048.13 EGF76217.1 - 9.6e-07 28.3 8.5 3.9e-05 23.0 8.6 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Virulence_RhuM PF13310.6 EGF76217.1 - 0.037 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Virulence protein RhuM family Ada_Zn_binding PF02805.16 EGF76218.1 - 2.4e-29 101.2 2.0 4.2e-29 100.4 2.0 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 EGF76218.1 - 3.4e-23 81.7 0.0 5.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EGF76218.1 - 8.7e-23 79.9 0.2 6.4e-12 45.2 0.0 2.6 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family Rrf2 PF02082.20 EGF76218.1 - 0.02 15.2 0.0 0.054 13.8 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator DNA_binding_1 PF01035.20 EGF76219.1 - 4.1e-30 103.7 0.0 5.4e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 EGF76219.1 - 5.2e-05 24.0 0.0 0.00047 20.9 0.0 2.3 1 1 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain HTH_18 PF12833.7 EGF76223.1 - 6.6e-19 68.0 0.3 1.6e-18 66.8 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EGF76223.1 - 2.6e-10 40.1 0.3 6.6e-06 26.1 0.2 3.2 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family TM_PBP2_N PF16296.5 EGF76223.1 - 0.013 15.6 0.2 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 N-terminal of TM subunit in PBP-dependent ABC transporters DUF3549 PF12069.8 EGF76223.1 - 0.029 13.4 0.1 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF1761 PF08570.10 EGF76224.1 - 8.3e-34 116.5 11.4 9.4e-34 116.4 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) DUF4149 PF13664.6 EGF76224.1 - 0.017 15.4 3.8 0.018 15.4 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) ABC2_membrane_5 PF13346.6 EGF76224.1 - 0.25 10.9 9.5 0.34 10.4 9.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3792 PF12670.7 EGF76224.1 - 4.4 7.5 18.5 11 6.2 14.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) SRA PF18491.1 EGF76225.1 - 4.1e-39 133.9 3.8 9.3e-39 132.7 3.8 1.6 1 0 0 1 1 1 1 SET and RING associated domain HTH_AraC PF00165.23 EGF76225.1 - 0.035 14.2 0.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Cyc-maltodext_C PF10438.9 EGF76225.1 - 0.038 14.1 0.5 0.19 11.8 1.4 1.8 2 1 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain CENP-N PF05238.13 EGF76227.1 - 0.00086 18.7 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Tudor_4 PF18358.1 EGF76227.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain DUF2207 PF09972.9 EGF76230.1 - 2.9e-29 102.2 7.1 2.9e-16 59.3 1.1 2.1 1 1 0 2 2 2 2 Predicted membrane protein (DUF2207) Wzy_C PF04932.15 EGF76230.1 - 0.075 12.7 0.9 0.16 11.6 0.4 1.8 2 0 0 2 2 2 0 O-Antigen ligase LprI PF07007.12 EGF76231.1 - 7.2e-11 42.7 0.9 1.1e-10 42.1 0.1 1.7 2 0 0 2 2 2 1 Lysozyme inhibitor LprI Presenilin PF01080.17 EGF76231.1 - 0.25 10.1 11.8 0.27 10.0 11.8 1.3 1 0 0 1 1 1 0 Presenilin DUF4969 PF16339.5 EGF76231.1 - 0.51 10.7 0.1 0.51 10.7 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4969) DUF1180 PF06679.12 EGF76231.1 - 0.94 9.9 7.7 2.5 8.5 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SpoIIIAH PF12685.7 EGF76231.1 - 0.98 9.2 26.2 5.8 6.7 26.2 1.9 1 1 0 1 1 1 0 SpoIIIAH-like protein Neur_chan_memb PF02932.16 EGF76231.1 - 1 9.4 3.0 1.6 8.7 3.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGF76231.1 - 1.5 8.0 5.0 1.6 7.9 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 EGF76231.1 - 2 6.6 16.0 3.1 6.0 16.0 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Menin PF05053.13 EGF76231.1 - 3.2 6.0 11.3 3.6 5.8 11.3 1.2 1 0 0 1 1 1 0 Menin G_glu_transpept PF01019.21 EGF76232.1 - 1.7e-171 571.5 0.0 1.9e-171 571.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UreE_N PF02814.15 EGF76232.1 - 0.082 12.5 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain DUF839 PF05787.13 EGF76233.1 - 1.9e-20 73.5 3.1 2.7e-20 73.0 3.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) DNA_methylase PF00145.17 EGF76234.1 - 8.3e-72 242.3 0.5 8.5e-70 235.7 0.5 2.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Striatin PF08232.12 EGF76235.1 - 0.0038 17.8 0.1 0.071 13.7 0.1 2.1 1 1 0 1 1 1 1 Striatin family Ribonuclease_3 PF00636.26 EGF76236.1 - 2e-19 70.2 0.2 6.6e-19 68.5 0.0 2.0 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF76236.1 - 1.4e-11 44.7 0.0 1.9e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like DUF4812 PF16071.5 EGF76240.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) GPS2_interact PF15784.5 EGF76243.1 - 0.021 15.3 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Keratin_2_head PF16208.5 EGF76243.1 - 0.099 12.8 14.9 0.31 11.2 11.5 2.4 2 0 0 2 2 2 0 Keratin type II head DASH_Dad2 PF08654.10 EGF76243.1 - 0.1 13.0 3.2 0.21 12.0 0.2 2.7 3 1 0 3 3 3 0 DASH complex subunit Dad2 Serglycin PF04360.12 EGF76243.1 - 0.1 12.5 4.6 2 8.3 0.1 2.7 2 0 0 2 2 2 0 Serglycin KRTAP PF11759.8 EGF76243.1 - 0.13 12.9 22.1 0.23 12.0 17.1 2.4 2 0 0 2 2 2 0 Keratin-associated matrix DUF1275 PF06912.11 EGF76244.1 - 1.8e-26 93.3 14.1 2.4e-26 92.9 14.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EGF76244.1 - 0.082 12.8 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 PIG-P DUF3792 PF12670.7 EGF76244.1 - 5.1 7.3 11.1 4.6 7.4 8.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) AAA_14 PF13173.6 EGF76249.1 - 0.00029 20.9 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF4478 PF14793.6 EGF76249.1 - 0.17 11.8 0.2 5.3 7.0 0.1 2.9 3 0 0 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Glyco_hydro_18 PF00704.28 EGF76252.1 - 4.5e-12 46.3 1.8 6.4e-12 45.8 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S49 PF01343.18 EGF76252.1 - 0.068 13.1 0.3 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 ERCC4 PF02732.15 EGF76253.1 - 7.1e-21 75.0 0.0 1.8e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain DUF4661 PF15576.6 EGF76253.1 - 0.13 12.2 1.5 0.26 11.2 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Cyclin PF08613.11 EGF76254.1 - 2.9e-06 27.7 0.8 8.1e-05 23.0 0.8 2.3 1 1 0 1 1 1 1 Cyclin PX PF00787.24 EGF76255.1 - 3.6e-09 36.6 3.5 9.9e-09 35.2 3.5 1.8 1 0 0 1 1 1 1 PX domain Ssu72 PF04722.13 EGF76256.1 - 1.7e-77 259.3 0.0 2e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein 6PF2K PF01591.18 EGF76257.1 - 1.4e-68 230.5 0.0 1.9e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGF76257.1 - 9.1e-30 103.8 0.0 2.7e-23 82.7 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGF76257.1 - 0.00033 20.8 0.0 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Hexapep PF00132.24 EGF76258.1 - 1.7e-07 30.7 14.9 7.1e-06 25.5 1.0 4.2 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGF76258.1 - 0.015 15.1 0.4 0.015 15.1 0.4 3.5 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGF76258.1 - 0.16 10.9 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 L-fucokinase TFIIE_alpha PF02002.17 EGF76259.1 - 3.4e-11 42.9 5.3 1.5e-10 40.9 5.3 2.0 1 1 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 EGF76259.1 - 0.014 15.5 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 EGF76259.1 - 0.29 11.6 0.1 0.29 11.6 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.25 EGF76260.1 - 2.4e-44 151.7 0.0 3.6e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76260.1 - 1.1e-28 100.3 0.0 1.7e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF76260.1 - 0.00015 21.8 0.1 0.028 14.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF76260.1 - 0.025 13.6 0.1 0.025 13.6 0.1 2.1 2 1 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 EGF76260.1 - 0.055 12.8 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Cyt-b5 PF00173.28 EGF76261.1 - 1e-12 48.0 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M1 PF01433.20 EGF76262.1 - 8.1e-85 283.8 1.4 1.2e-84 283.2 0.6 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGF76262.1 - 2.7e-57 194.7 1.1 2.7e-57 194.7 1.1 2.4 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGF76262.1 - 8.9e-51 172.7 2.9 2.2e-50 171.4 2.9 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EGF76262.1 - 0.00015 21.7 0.2 0.00032 20.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF4695 PF15766.5 EGF76262.1 - 0.012 15.8 0.7 0.031 14.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF3458 PF11940.8 EGF76262.1 - 0.098 13.1 0.3 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold RhoGAP PF00620.27 EGF76263.1 - 0.0093 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain RasGAP PF00616.19 EGF76263.1 - 0.2 11.4 2.5 0.51 10.0 2.5 1.7 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase CGI-121 PF08617.10 EGF76264.1 - 3e-26 92.5 0.9 3.8e-26 92.1 0.9 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AMA-1 PF02430.15 EGF76264.1 - 0.064 12.2 0.1 0.076 12.0 0.1 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 SKA1 PF07160.12 EGF76265.1 - 9.6e-68 228.6 0.1 1.1e-67 228.3 0.1 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF5082 PF16888.5 EGF76265.1 - 0.84 9.9 4.2 1.3 9.3 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Rod_C PF10493.9 EGF76266.1 - 3.3e-32 111.6 12.9 1.1e-31 109.9 12.9 1.8 1 0 0 1 1 1 1 Rough deal protein C-terminal region CPSF_A PF03178.15 EGF76266.1 - 0.0095 15.3 0.1 0.025 13.9 0.1 1.7 1 0 0 1 1 1 1 CPSF A subunit region SCP2 PF02036.17 EGF76267.1 - 7.9e-07 29.5 0.0 1.3e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 SCP-2 sterol transfer family PPR_3 PF13812.6 EGF76268.1 - 0.015 15.3 0.1 1.9 8.6 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain ATP13 PF12921.7 EGF76268.1 - 0.027 14.3 3.8 0.2 11.5 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ATPase expression PPR_2 PF13041.6 EGF76268.1 - 0.056 13.7 0.1 6.4 7.1 0.0 3.8 5 0 0 5 5 5 0 PPR repeat family PPR PF01535.20 EGF76268.1 - 0.072 13.4 0.0 51 4.4 0.0 4.1 5 0 0 5 5 5 0 PPR repeat DUF1765 PF08578.10 EGF76268.1 - 0.1 13.1 1.4 0.39 11.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) Pkinase PF00069.25 EGF76269.1 - 7.1e-66 222.3 0.0 1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76269.1 - 4.9e-32 111.2 0.0 6.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF76269.1 - 6.1e-06 25.4 0.3 1.1e-05 24.5 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGF76269.1 - 0.00023 20.6 0.1 0.00037 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF76269.1 - 0.00069 19.6 0.3 0.045 13.7 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF76269.1 - 0.00075 18.4 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 EGF76270.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTP_transferase PF00483.23 EGF76271.1 - 3.3e-31 108.8 0.0 4.6e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGF76271.1 - 9.2e-12 44.2 11.7 1.8e-07 30.6 0.2 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGF76271.1 - 0.00029 21.2 0.0 0.00068 20.0 0.0 1.6 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EGF76271.1 - 0.0037 15.5 0.0 0.0086 14.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGF76271.1 - 0.053 13.3 6.6 0.47 10.2 0.1 3.7 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase LCCL PF03815.19 EGF76272.1 - 0.061 13.4 0.2 0.078 13.1 0.2 1.2 1 0 0 1 1 1 0 LCCL domain Pyr_redox_2 PF07992.14 EGF76274.1 - 1.4e-51 175.5 3.0 1.8e-51 175.2 3.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGF76274.1 - 1.1e-16 60.6 0.0 2.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EGF76274.1 - 1.7e-15 57.3 4.8 8.1e-09 35.9 0.2 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGF76274.1 - 3.9e-09 36.2 2.1 2.8e-06 26.8 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EGF76274.1 - 1.3e-08 34.6 0.1 1e-07 31.8 0.0 2.4 2 1 1 3 3 3 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 EGF76274.1 - 5.3e-08 33.3 0.0 1.4e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.14 EGF76274.1 - 1.2e-05 24.3 0.2 0.091 11.4 0.2 2.6 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 EGF76274.1 - 2.3e-05 24.1 5.5 0.064 12.8 0.0 4.4 6 0 0 6 6 6 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGF76274.1 - 0.00015 21.8 1.2 0.91 9.5 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGF76274.1 - 0.00023 20.4 6.1 0.0014 17.7 0.3 3.0 4 0 0 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 EGF76274.1 - 0.00039 20.6 2.7 0.0018 18.4 0.3 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGF76274.1 - 0.00045 19.6 0.5 0.058 12.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 EGF76274.1 - 0.017 15.6 0.7 0.65 10.5 0.1 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 EGF76274.1 - 0.5 9.6 4.3 2.4 7.3 0.1 2.8 3 0 0 3 3 3 0 Thi4 family MORN PF02493.20 EGF76275.1 - 2.4e-28 96.3 34.3 1.2e-05 24.9 1.1 7.3 7 0 0 7 7 7 7 MORN repeat DUF3048_C PF17479.2 EGF76275.1 - 0.038 14.4 12.5 1.5 9.2 0.3 4.5 2 2 4 6 6 6 0 Protein of unknown function (DUF3048) C-terminal domain Ribosomal_L30 PF00327.20 EGF76276.1 - 8.1e-11 41.6 0.3 9e-11 41.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PP28 PF10252.9 EGF76277.1 - 1.5e-25 89.4 12.5 2.5e-25 88.7 12.5 1.3 1 0 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 SVIP PF15811.5 EGF76278.1 - 0.0029 18.0 2.9 0.0049 17.3 2.9 1.4 1 1 0 1 1 1 1 Small VCP/p97-interacting protein EF-1_beta_acid PF10587.9 EGF76278.1 - 0.089 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region LRR_9 PF14580.6 EGF76279.1 - 7.5e-15 54.9 1.4 7.5e-15 54.9 1.4 2.9 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 EGF76279.1 - 6.2e-13 48.7 24.6 6.3e-08 32.8 2.4 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF76279.1 - 1.9e-12 46.8 17.9 1.8e-09 37.2 5.9 4.5 3 2 2 5 5 5 4 Leucine rich repeat sCache_like PF16736.5 EGF76279.1 - 0.1 12.7 0.3 0.1 12.7 0.3 2.9 3 1 0 3 3 3 0 Single Cache-like GUCT PF08152.12 EGF76279.1 - 2.7 8.3 6.9 22 5.5 0.2 3.4 4 0 0 4 4 4 0 GUCT (NUC152) domain DSS1_SEM1 PF05160.13 EGF76280.1 - 7.9e-15 54.7 16.1 1e-14 54.3 16.1 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family EF-hand_7 PF13499.6 EGF76281.1 - 5.1e-08 33.2 2.2 7.5e-08 32.7 2.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGF76281.1 - 7e-06 25.8 1.9 0.049 13.5 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF76281.1 - 8.7e-06 24.9 2.0 0.00081 18.8 0.3 2.4 2 0 0 2 2 2 2 EF hand EF_assoc_2 PF08356.12 EGF76281.1 - 5.3e-05 23.1 0.2 9.1e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.6 EGF76281.1 - 0.00011 21.8 1.2 0.0064 16.3 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF_assoc_1 PF08355.12 EGF76281.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 EF hand associated EF-hand_5 PF13202.6 EGF76281.1 - 0.0076 15.7 0.7 0.024 14.1 0.7 1.8 1 0 0 1 1 1 1 EF hand Skp1 PF01466.19 EGF76281.1 - 0.066 13.3 0.3 0.23 11.6 0.1 2.1 1 1 1 2 2 2 0 Skp1 family, dimerisation domain ABC_transp_aux PF09822.9 EGF76281.1 - 0.072 12.5 0.1 0.073 12.5 0.1 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system CD34_antigen PF06365.12 EGF76282.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 CD34/Podocalyxin family MIP PF00230.20 EGF76283.1 - 1.7e-36 126.0 9.4 8.2e-36 123.8 9.4 1.9 1 1 0 1 1 1 1 Major intrinsic protein Mis12 PF05859.12 EGF76283.1 - 4e-23 82.0 0.3 7.9e-23 81.0 0.3 1.5 1 0 0 1 1 1 1 Mis12 protein PspC PF04024.12 EGF76283.1 - 0.05 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 PspC domain AA_kinase PF00696.28 EGF76284.1 - 1.1e-38 133.2 0.0 1.6e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EGF76284.1 - 3.3e-13 49.2 1.1 2.3e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EGF76284.1 - 1.2e-10 41.0 0.6 6.4e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 ACT domain COMPASS-Shg1 PF05205.12 EGF76284.1 - 0.086 13.6 0.1 0.24 12.1 0.1 1.8 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3631 PF12307.8 EGF76284.1 - 0.11 12.7 0.0 0.73 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3631) Peroxin-13_N PF04088.13 EGF76285.1 - 2.6e-38 131.6 7.4 2.8e-37 128.2 7.4 2.0 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 EGF76285.1 - 1.7e-09 37.2 0.1 1.3e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGF76285.1 - 3.9e-08 32.9 0.0 1.1e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EGF76285.1 - 2.6e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.14 EGF76285.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region BK_channel_a PF03493.18 EGF76286.1 - 3.6e-20 72.0 0.0 4.5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit MoaC PF01967.21 EGF76287.1 - 3.8e-51 172.7 7.4 6.9e-51 171.9 7.4 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EGF76287.1 - 7.2e-38 129.4 0.0 1.5e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGF76287.1 - 6.6e-28 98.2 0.0 1.1e-27 97.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGF76287.1 - 1e-06 29.1 0.0 2.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGF76287.1 - 0.00026 21.1 0.1 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Dockerin_1 PF00404.18 EGF76287.1 - 0.033 14.4 0.3 4.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Dockerin type I domain Pkinase PF00069.25 EGF76288.1 - 4.5e-48 163.9 0.0 3.1e-43 148.0 0.0 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76288.1 - 3.1e-18 66.0 0.0 5.1e-13 48.9 0.1 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGF76288.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF76288.1 - 0.024 13.9 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RLI PF04068.15 EGF76289.1 - 0.05 13.4 3.5 0.098 12.5 3.5 1.5 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI Importin_rep PF18773.1 EGF76290.1 - 1.5e-10 40.6 0.2 4.4e-10 39.1 0.2 1.9 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 EGF76290.1 - 8.7e-07 28.9 2.9 1.2e-06 28.4 0.1 2.9 3 0 0 3 3 3 1 Importin 13 repeat HEAT_2 PF13646.6 EGF76290.1 - 5.7e-06 26.6 0.0 0.063 13.7 0.0 3.8 2 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 EGF76290.1 - 0.0036 17.4 2.7 18 5.4 0.0 4.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 EGF76290.1 - 0.095 12.8 0.2 0.095 12.8 0.2 4.7 3 3 1 5 5 5 0 Exportin 1-like protein HEAT PF02985.22 EGF76290.1 - 0.099 13.0 0.8 7.8 7.0 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat PIP49_C PF12260.8 EGF76290.1 - 7.6 6.1 9.7 0.13 11.8 0.7 2.5 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Metallophos PF00149.28 EGF76291.1 - 1.5e-16 61.6 4.7 1.9e-16 61.2 4.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGF76291.1 - 1.5e-05 25.2 0.0 0.00028 21.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SPA PF08616.10 EGF76293.1 - 1.4e-28 99.1 0.0 3.6e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EGF76293.1 - 1.9e-13 51.0 0.0 5.6e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EGF76293.1 - 2.2e-06 26.6 0.0 0.068 11.9 0.0 3.1 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 EGF76293.1 - 4e-06 26.6 0.0 0.001 18.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) TIP120 PF08623.10 EGF76293.1 - 0.042 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) ANAPC4_WD40 PF12894.7 EGF76294.1 - 1.6e-06 28.3 0.0 0.0043 17.3 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF76294.1 - 3.5e-06 27.7 0.2 0.0032 18.3 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGF76294.1 - 0.013 14.5 0.6 0.16 10.9 0.1 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IQ PF00612.27 EGF76295.1 - 0.3 11.0 0.9 0.75 9.8 0.9 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif ERp29 PF07749.12 EGF76295.1 - 1.7 9.6 5.1 1.6 9.7 0.0 3.2 2 1 2 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain Lactamase_B PF00753.27 EGF76296.1 - 2.3e-12 47.3 0.5 8e-06 26.0 0.4 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily TPR_1 PF00515.28 EGF76296.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76296.1 - 0.067 13.4 0.1 0.32 11.3 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FHA PF00498.26 EGF76297.1 - 2.4e-10 40.6 0.3 7.1e-10 39.1 0.3 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGF76297.1 - 0.0086 16.4 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PMSR PF01625.21 EGF76298.1 - 1.2e-59 200.9 0.8 1.5e-59 200.6 0.8 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PDZ PF00595.24 EGF76299.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 PDZ domain Dynein_light PF01221.18 EGF76301.1 - 0.19 12.1 1.2 0.41 11.0 1.2 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 WDCP PF15390.6 EGF76302.1 - 0.24 9.7 3.0 0.33 9.3 3.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4558 PF15104.6 EGF76302.1 - 0.76 9.9 4.6 12 6.1 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4558) AAA_29 PF13555.6 EGF76303.1 - 0.17 11.7 0.1 28 4.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Asp PF00026.23 EGF76304.1 - 4.3e-12 46.1 0.0 1.5e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76304.1 - 0.0011 18.8 0.0 0.0058 16.4 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF76304.1 - 0.052 14.1 0.0 16 6.1 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Tom22 PF04281.13 EGF76305.1 - 7.3 6.4 7.6 0.29 10.9 1.3 1.9 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 WDCP PF15390.6 EGF76306.1 - 2.1 6.7 12.4 7.6 4.8 12.2 1.7 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MRI PF15325.6 EGF76306.1 - 2.5 9.2 10.4 0.64 11.1 4.9 2.5 1 1 1 2 2 2 0 Modulator of retrovirus infection Hid1 PF12722.7 EGF76306.1 - 3.5 5.6 13.2 2.9 5.9 12.4 1.3 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 EGF76306.1 - 7.6 5.1 12.1 9 4.9 12.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Asp PF00026.23 EGF76308.1 - 4e-14 52.8 1.7 6.9e-13 48.7 1.7 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76308.1 - 2.7e-05 24.0 0.0 0.00027 20.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Thr_synth_N PF14821.6 EGF76310.1 - 1.4e-28 98.9 0.0 6.3e-28 96.8 0.0 2.3 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EGF76310.1 - 1.7e-15 57.2 0.0 4.7e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BCAS3 PF12490.8 EGF76311.1 - 0.015 14.8 0.9 0.064 12.8 0.9 2.0 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 3 Velvet PF11754.8 EGF76312.1 - 1.2e-56 192.4 5.8 1.2e-56 192.4 5.8 2.6 2 1 0 2 2 2 1 Velvet factor DUF5600 PF18150.1 EGF76313.1 - 1.9e-36 124.9 0.9 3.5e-36 124.0 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 EGF76313.1 - 4.9e-14 52.7 0.0 1.4e-12 48.0 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.7 EGF76313.1 - 2.8e-11 43.3 0.0 1.7e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.23 EGF76313.1 - 8.5e-10 38.7 0.0 2.1e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 EGF76313.1 - 1.5e-06 28.0 0.0 3.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein EF-hand_1 PF00036.32 EGF76313.1 - 0.00099 18.5 0.0 0.0045 16.4 0.0 2.1 2 0 0 2 2 2 1 EF hand RsgA_GTPase PF03193.16 EGF76313.1 - 0.0015 18.5 0.1 0.76 9.7 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EGF76313.1 - 0.0018 17.8 0.0 0.0076 15.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EGF76313.1 - 0.0028 17.9 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 EGF76313.1 - 0.078 12.9 0.0 0.38 10.8 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain TsaE PF02367.17 EGF76313.1 - 0.094 12.7 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 EGF76313.1 - 0.099 12.2 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EGF76313.1 - 0.13 11.6 0.1 5.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AIG1 PF04548.16 EGF76313.1 - 0.15 11.4 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 AIG1 family DUF4272 PF14094.6 EGF76313.1 - 0.17 11.1 0.3 1.6 8.0 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4272) PduV-EutP PF10662.9 EGF76313.1 - 0.19 11.5 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M22 PF00814.25 EGF76316.1 - 2.2e-86 289.9 0.0 2.6e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGF76316.1 - 0.00092 19.0 0.0 0.048 13.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus LMBR1 PF04791.16 EGF76317.1 - 8.5e-12 44.8 24.4 9.4e-12 44.6 19.1 2.7 2 1 0 2 2 2 1 LMBR1-like membrane protein tRNA-synt_1g PF09334.11 EGF76318.1 - 1e-99 333.9 2.5 2.4e-98 329.4 2.5 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGF76318.1 - 1.2e-20 73.4 2.4 9.4e-10 37.4 0.3 3.2 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGF76318.1 - 3.3e-11 43.1 0.0 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EGF76318.1 - 0.0034 17.4 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 EGF76318.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) Peptidase_S41 PF03572.18 EGF76319.1 - 5.6e-15 55.3 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Peptidase_S41 PF03572.18 EGF76320.1 - 2e-16 60.0 0.0 3.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Peptidase_S41 PF03572.18 EGF76321.1 - 1.8e-16 60.2 0.0 3.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PIP5K PF01504.18 EGF76322.1 - 6.4e-47 160.1 0.0 1.4e-45 155.7 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Ras PF00071.22 EGF76323.1 - 9.2e-23 80.6 0.0 1e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF76323.1 - 8e-06 26.1 0.0 1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DAGAT PF03982.13 EGF76324.1 - 4.7e-108 360.6 0.0 5.7e-108 360.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4018 PF13210.6 EGF76324.1 - 0.029 14.1 0.6 0.061 13.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Pex24p PF06398.11 EGF76324.1 - 0.21 10.5 2.1 0.35 9.8 2.1 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PIN_4 PF13638.6 EGF76325.1 - 6.1e-18 65.4 3.4 8.9e-18 64.8 0.0 2.4 1 1 1 2 2 2 1 PIN domain KTI12 PF08433.10 EGF76326.1 - 2.5e-80 269.9 0.0 2.8e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGF76326.1 - 0.00033 20.8 0.0 0.00083 19.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EGF76326.1 - 0.07 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA PF00004.29 EGF76326.1 - 0.072 13.5 0.1 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GrpE PF01025.19 EGF76328.1 - 0.0054 16.4 0.9 0.0076 15.9 0.9 1.2 1 0 0 1 1 1 1 GrpE CRT10 PF08728.10 EGF76328.1 - 0.014 13.6 0.0 0.016 13.4 0.0 1.0 1 0 0 1 1 1 0 CRT10 NOG1_N PF17835.1 EGF76328.1 - 0.023 14.7 0.4 0.029 14.4 0.4 1.1 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Syntaxin-6_N PF09177.11 EGF76328.1 - 0.073 13.6 1.7 0.1 13.2 1.7 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal GCV_T_C PF08669.11 EGF76328.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain RhoGEF PF00621.20 EGF76329.1 - 1.7e-12 48.0 6.6 1.7e-12 48.0 6.6 3.0 3 0 0 3 3 3 1 RhoGEF domain RhoGAP PF00620.27 EGF76329.1 - 4.2e-12 46.2 0.2 1.7e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain ChAPs PF09295.10 EGF76330.1 - 1.6e-127 425.8 0.0 2.5e-127 425.2 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EGF76330.1 - 1.7e-06 28.5 4.4 0.0064 17.0 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF76330.1 - 0.0084 16.9 11.9 4.1 8.5 0.2 5.9 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76330.1 - 0.0087 16.2 11.1 0.69 10.3 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF76330.1 - 0.04 14.1 0.2 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76330.1 - 0.25 11.6 10.1 10 6.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF76330.1 - 4.2 8.1 7.3 1.7 9.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 EGF76332.1 - 2.5e-52 177.9 0.0 4e-52 177.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76332.1 - 2.3e-32 112.3 0.0 3.6e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF76332.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like DUF3725 PF12523.8 EGF76332.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) Staphylokinase PF02821.16 EGF76332.1 - 0.12 12.8 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family Nsp1_C PF05064.13 EGF76333.1 - 2.1 8.2 14.5 0.033 14.0 3.5 3.0 1 1 0 2 2 2 0 Nsp1-like C-terminal region Tam41_Mmp37 PF09139.11 EGF76334.1 - 1.5e-110 369.7 0.1 1.8e-110 369.4 0.1 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Myb_DNA-binding PF00249.31 EGF76335.1 - 4.8e-15 55.5 0.0 8.9e-07 29.0 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF76335.1 - 3.3e-13 49.7 0.0 2e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_transf_8C PF08437.10 EGF76335.1 - 0.033 14.3 0.7 0.11 12.7 0.7 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Peripla_BP_7 PF18610.1 EGF76335.1 - 0.048 13.8 0.8 0.25 11.5 0.6 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain Peptidase_S41 PF03572.18 EGF76336.1 - 6.4e-11 42.1 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 HTH_Tnp_1_2 PF13022.6 EGF76336.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase DUF2046 PF09755.9 EGF76337.1 - 1.2e-27 96.9 22.5 1.2e-27 96.9 22.5 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) PIN_8 PF18476.1 EGF76337.1 - 0.23 11.3 5.5 0.18 11.6 3.8 1.7 1 1 0 1 1 1 0 PIN like domain FAM76 PF16046.5 EGF76337.1 - 1.1 8.5 18.8 0.0097 15.3 7.3 2.4 1 1 2 3 3 3 0 FAM76 protein LCIB_C_CA PF18599.1 EGF76337.1 - 1.2 8.4 5.6 2.2 7.5 5.0 1.7 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases ABC_tran PF00005.27 EGF76338.1 - 1.2e-55 187.7 1.1 1.7e-33 116.0 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGF76338.1 - 2.9e-49 168.2 23.0 1.1e-24 87.5 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGF76338.1 - 3.4e-09 36.5 5.4 0.00045 19.7 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF76338.1 - 2.5e-08 34.0 0.1 0.0039 17.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGF76338.1 - 7.3e-07 29.7 1.2 0.023 15.1 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGF76338.1 - 1.5e-06 27.9 1.9 0.044 13.5 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF76338.1 - 9.6e-06 25.6 0.2 0.11 12.3 0.0 3.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EGF76338.1 - 9.6e-06 25.8 0.8 0.026 14.6 0.2 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 EGF76338.1 - 1.2e-05 25.4 0.8 0.011 15.8 0.2 2.6 2 0 0 2 2 2 2 Dynamin family TrwB_AAD_bind PF10412.9 EGF76338.1 - 0.00014 20.9 0.4 0.44 9.4 0.1 2.5 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EGF76338.1 - 0.00026 21.3 1.7 1.2 9.4 0.5 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGF76338.1 - 0.00049 20.0 0.8 0.23 11.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGF76338.1 - 0.00069 20.2 0.6 1.3 9.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGF76338.1 - 0.00099 18.2 0.1 0.029 13.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF815 PF05673.13 EGF76338.1 - 0.001 18.3 0.4 1.4 8.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGF76338.1 - 0.0016 18.0 0.2 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 EGF76338.1 - 0.0018 18.5 0.3 1.9 8.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EGF76338.1 - 0.0022 17.7 1.0 1.1 8.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 EGF76338.1 - 0.0035 16.9 1.2 2 8.0 0.2 3.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EGF76338.1 - 0.0038 16.6 0.3 0.77 9.1 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.27 EGF76338.1 - 0.0069 15.9 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 EGF76338.1 - 0.0071 15.8 0.3 1.1 8.6 0.1 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein NACHT PF05729.12 EGF76338.1 - 0.012 15.5 3.2 3.8 7.4 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.6 EGF76338.1 - 0.02 14.7 0.2 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 EGF76338.1 - 0.028 14.1 0.1 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 EGF76338.1 - 0.03 14.2 1.4 1 9.2 0.2 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EGF76338.1 - 0.039 13.7 0.3 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EGF76338.1 - 0.053 14.1 0.0 8.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGF76338.1 - 0.06 13.1 0.5 5.4 6.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EGF76338.1 - 0.06 12.3 0.6 1.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGF76338.1 - 0.08 12.5 1.4 7.6 6.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGF76338.1 - 0.098 11.8 1.0 2.8 7.1 0.1 2.4 3 0 0 3 3 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 EGF76338.1 - 0.1 12.5 0.1 13 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EGF76338.1 - 0.12 12.8 0.1 28 5.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 EGF76338.1 - 0.13 12.1 0.8 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 NTPase IIGP PF05049.13 EGF76338.1 - 0.18 10.9 0.6 2.3 7.2 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 EGF76338.1 - 0.19 11.5 0.2 8.4 6.0 0.1 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Phi_1 PF04674.12 EGF76339.1 - 1.3e-37 129.7 0.6 2.6e-37 128.6 0.6 1.6 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region Ice_nucleation PF00818.17 EGF76339.1 - 0.78 9.9 4.0 3.9 7.7 4.0 2.3 1 0 0 1 1 1 0 Ice nucleation protein repeat CRAL_TRIO PF00650.20 EGF76340.1 - 1.9e-30 105.7 0.2 5.3e-29 101.0 0.1 2.3 2 0 0 2 2 2 1 CRAL/TRIO domain VATC PF18716.1 EGF76340.1 - 0.12 12.2 1.1 0.35 10.7 0.3 2.0 2 0 0 2 2 2 0 Vms1-associating treble clef domain Spore_GerAC PF05504.11 EGF76341.1 - 0.031 14.5 2.5 0.064 13.5 0.6 2.1 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal FliG_N PF14842.6 EGF76341.1 - 0.23 12.0 2.5 0.48 11.0 2.2 1.6 1 1 1 2 2 2 0 FliG N-terminal domain MOZ_SAS PF01853.18 EGF76345.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.0 1 0 0 1 1 1 0 MOZ/SAS family PAG PF15347.6 EGF76346.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Prok-RING_4 PF14447.6 EGF76347.1 - 0.35 10.8 2.1 0.61 10.0 0.0 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Baculo_PEP_N PF04512.12 EGF76348.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Ribonuclease_3 PF00636.26 EGF76349.1 - 6.1e-19 68.6 0.1 1.9e-18 67.0 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF76349.1 - 2.7e-11 43.7 0.0 5.1e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Asp PF00026.23 EGF76352.1 - 6.4e-12 45.5 0.0 1.5e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76352.1 - 0.0021 17.9 0.0 0.02 14.6 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HNH_2 PF13391.6 EGF76353.1 - 5.2e-06 26.5 0.2 0.00051 20.1 0.0 2.8 2 0 0 2 2 2 2 HNH endonuclease Zip PF02535.22 EGF76355.1 - 0.94 8.6 5.3 1.6 7.9 5.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter BRE1 PF08647.11 EGF76355.1 - 1.3 9.2 13.2 0.095 12.8 0.8 3.4 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Neur_chan_memb PF02932.16 EGF76355.1 - 4.5 7.2 10.6 1.6 8.7 6.2 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 EGF76355.1 - 5.6 6.7 9.4 0.52 10.1 4.3 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Mac PF12464.8 EGF76356.1 - 0.064 13.5 1.1 0.19 12.0 1.1 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase gag_pre-integrs PF13976.6 EGF76357.1 - 1.9e-07 30.8 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 EGF76357.1 - 0.00037 20.1 0.3 0.0008 19.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 EGF76357.1 - 0.081 12.6 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF76357.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Vac17 PF17321.2 EGF76357.1 - 0.11 12.0 0.9 0.97 8.8 0.7 2.1 2 0 0 2 2 2 0 Vacuole-related protein 17 PPR_2 PF13041.6 EGF76360.1 - 6.2e-06 26.3 0.1 0.075 13.2 0.0 2.9 2 1 0 2 2 2 2 PPR repeat family PPR PF01535.20 EGF76360.1 - 0.0084 16.3 0.0 1.6 9.2 0.0 4.0 4 0 0 4 4 4 1 PPR repeat Fungus-induced PF10917.8 EGF76361.1 - 0.048 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Fungus-induced protein Fungus-induced PF10917.8 EGF76362.1 - 0.028 14.7 1.6 0.11 12.9 0.0 2.4 1 1 1 2 2 2 0 Fungus-induced protein PAF-AH_p_II PF03403.13 EGF76363.1 - 2.6e-41 141.4 0.0 3.2e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 EGF76363.1 - 0.00065 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EGF76363.1 - 0.0058 15.6 0.0 0.062 12.2 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGF76363.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Nup160 PF11715.8 EGF76364.1 - 1.7e-26 93.0 1.3 1.1e-17 64.0 0.1 3.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HMG_box PF00505.19 EGF76365.1 - 2e-16 60.1 0.0 2.2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF76365.1 - 2.3e-08 34.5 0.0 2.7e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 HMG-box domain NAD_Gly3P_dh_C PF07479.14 EGF76366.1 - 1.7e-51 174.2 0.8 2.7e-51 173.6 0.8 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EGF76366.1 - 2.1e-36 125.3 0.0 3.5e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EGF76366.1 - 2.8e-08 33.5 0.1 4.5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EGF76366.1 - 1.1e-06 29.1 0.1 5.2e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 EGF76366.1 - 3.2e-05 24.4 0.1 0.002 18.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EGF76366.1 - 3.6e-05 24.0 0.1 0.00012 22.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGF76366.1 - 0.00033 20.7 0.1 0.0018 18.3 0.0 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EGF76366.1 - 0.00036 20.1 0.1 0.0018 17.9 0.1 2.0 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EGF76366.1 - 0.00072 20.0 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EGF76366.1 - 0.00078 18.8 0.0 0.002 17.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EGF76366.1 - 0.0061 16.8 0.3 0.052 13.8 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.6 EGF76366.1 - 0.0064 15.8 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGF76366.1 - 0.0083 15.7 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1495 PF07381.11 EGF76366.1 - 0.022 14.6 0.0 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) PDH PF02153.17 EGF76366.1 - 0.048 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_binding_8 PF13450.6 EGF76366.1 - 0.053 13.7 0.1 0.39 11.0 0.0 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Peptidase_C15 PF01470.17 EGF76366.1 - 0.11 12.6 0.2 0.81 9.8 0.0 2.0 2 0 0 2 2 2 0 Pyroglutamyl peptidase EF-hand_1 PF00036.32 EGF76367.1 - 3e-31 104.6 18.8 3.2e-09 35.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGF76367.1 - 2.8e-29 101.3 10.7 1.4e-15 57.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGF76367.1 - 1.9e-25 86.6 9.6 2.7e-09 36.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGF76367.1 - 4.7e-25 87.2 11.5 3.3e-12 46.1 1.2 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGF76367.1 - 1.2e-15 57.6 0.3 1.6e-07 31.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGF76367.1 - 1.2e-13 49.9 19.1 8.2e-06 25.1 0.2 4.6 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 EGF76367.1 - 3.5e-05 23.7 7.9 0.13 12.2 1.2 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Sigma54_CBD PF04963.13 EGF76367.1 - 0.00061 19.7 1.8 0.0008 19.3 1.8 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain SPARC_Ca_bdg PF10591.9 EGF76367.1 - 0.0011 19.3 5.0 0.023 15.0 0.3 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EGF76367.1 - 0.0018 18.6 6.3 0.26 11.6 0.3 3.1 1 1 2 3 3 3 2 EF-hand domain SpaA PF17802.1 EGF76367.1 - 0.016 15.5 2.3 0.57 10.5 0.3 2.4 2 1 0 2 2 2 0 Prealbumin-like fold domain Dockerin_1 PF00404.18 EGF76367.1 - 0.018 15.2 1.5 0.053 13.7 0.2 2.2 2 1 1 3 3 3 0 Dockerin type I domain SUB1_ProdP9 PF18213.1 EGF76367.1 - 0.028 14.3 0.7 0.052 13.4 0.5 1.6 1 1 0 1 1 1 0 SUB1 protease Prodomain ProdP9 EF-hand_11 PF08976.11 EGF76367.1 - 0.028 15.3 0.3 0.81 10.6 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 EGF76367.1 - 0.048 13.4 7.5 1 9.2 3.0 2.1 1 1 1 2 2 2 0 SurA N-terminal domain Acetyltransf_11 PF13720.6 EGF76367.1 - 0.11 13.0 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Caleosin PF05042.13 EGF76367.1 - 0.21 11.5 1.2 7.9 6.4 0.0 3.2 1 1 3 4 4 4 0 Caleosin related protein DUF3349 PF11829.8 EGF76367.1 - 0.22 12.3 1.8 33 5.3 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) Gp-FAR-1 PF05823.12 EGF76367.1 - 0.37 11.1 7.9 2.1 8.7 0.2 3.2 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SurA_N_2 PF13623.6 EGF76367.1 - 0.45 10.4 9.0 2 8.3 0.3 2.7 1 1 1 2 2 2 0 SurA N-terminal domain DUF2722 PF10846.8 EGF76367.1 - 0.91 8.4 10.9 0.89 8.4 10.9 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) SRI PF08236.11 EGF76367.1 - 3.4 7.9 9.6 1.1 9.4 0.1 3.5 3 1 1 4 4 4 0 SRI (Set2 Rpb1 interacting) domain LETM1 PF07766.13 EGF76367.1 - 5.6 6.2 8.6 0.6 9.4 1.1 2.5 1 1 1 2 2 2 0 LETM1-like protein GRAM PF02893.20 EGF76368.1 - 6.5e-13 48.6 0.1 1.6e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 GRAM domain Chordopox_A13L PF05961.11 EGF76368.1 - 0.015 15.5 0.1 0.049 13.9 0.1 1.9 1 0 0 1 1 1 0 Chordopoxvirus A13L protein WRW PF10206.9 EGF76368.1 - 0.072 13.5 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f IBN_N PF03810.19 EGF76368.1 - 0.092 12.7 1.1 9.2 6.3 0.1 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain Adeno_E3B PF03376.14 EGF76368.1 - 0.13 12.5 0.5 0.29 11.4 0.5 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein DUF2730 PF10805.8 EGF76368.1 - 0.13 12.3 1.1 0.54 10.4 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4834 PF16118.5 EGF76368.1 - 0.2 12.6 3.5 0.27 12.2 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 EGF76368.1 - 2.6 6.4 12.0 0.059 11.8 4.8 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Vac7 PF12751.7 EGF76369.1 - 6.3e-12 45.6 1.3 1.1e-11 44.8 1.3 1.4 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 GP17 PF17420.2 EGF76369.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 ELFV_dehydrog PF00208.21 EGF76371.1 - 1.1e-59 202.1 0.0 1.6e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EGF76371.1 - 2.7e-22 78.3 0.0 1.2e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EGF76371.1 - 0.072 13.0 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FB_lectin PF07367.11 EGF76373.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Fungal fruit body lectin Polysacc_deac_1 PF01522.21 EGF76374.1 - 1.1e-32 112.6 0.1 2.6e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 EGF76374.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 EGF76374.1 - 0.0059 15.8 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 TMEM52 PF14979.6 EGF76374.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 zf-RING_2 PF13639.6 EGF76376.1 - 1.5e-08 34.8 6.4 2.4e-08 34.2 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGF76376.1 - 9.1e-06 25.6 2.2 1.6e-05 24.9 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGF76376.1 - 1.5e-05 25.2 8.4 3.7e-05 23.9 8.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF76376.1 - 3.3e-05 23.7 7.5 5.1e-05 23.1 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGF76376.1 - 3.9e-05 23.7 8.3 0.00021 21.4 8.3 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EGF76376.1 - 0.00041 20.4 6.4 0.00072 19.6 6.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 EGF76376.1 - 0.0089 16.3 7.1 0.026 14.8 7.1 1.8 1 1 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.6 EGF76376.1 - 0.0092 15.8 5.4 0.025 14.4 5.4 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGF76376.1 - 0.018 14.6 5.1 0.037 13.6 5.1 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGF76376.1 - 0.022 14.6 10.0 0.081 12.8 10.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EGF76376.1 - 0.027 14.4 3.2 0.027 14.4 3.2 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EGF76376.1 - 0.085 12.8 8.0 0.08 12.8 6.7 1.7 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.6 EGF76376.1 - 0.12 12.3 8.5 1.4 8.8 8.4 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 EGF76376.1 - 0.16 12.0 6.7 0.4 10.6 6.7 1.7 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 EGF76376.1 - 0.56 10.4 5.4 0.41 10.8 3.2 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C2H2_aberr PF17017.5 EGF76377.1 - 6.3e-09 36.2 1.4 1.5e-08 35.0 1.4 1.6 1 0 0 1 1 1 1 Aberrant zinc-finger Peptidase_S8 PF00082.22 EGF76378.1 - 3.2e-78 263.0 0.9 5.6e-78 262.2 0.9 1.4 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 EGF76378.1 - 1.4e-59 200.8 0.0 2.3e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Tripeptidyl peptidase II CTC1 PF15489.6 EGF76379.1 - 4.3e-19 67.7 6.3 1e-11 43.2 1.3 3.0 3 0 0 3 3 3 3 CST, telomere maintenance, complex subunit CTC1 CTC1_2 PF15491.6 EGF76379.1 - 0.0017 17.7 0.0 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 CST, telomere maintenance, complex subunit CTC1 DUF5607 PF18355.1 EGF76380.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Chorion_2 PF03964.15 EGF76380.1 - 0.24 12.3 0.1 0.77 10.6 0.2 1.7 2 0 0 2 2 2 0 Chorion family 2 SAM_2 PF07647.17 EGF76381.1 - 0.0057 16.8 0.3 0.013 15.6 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2408 PF10303.9 EGF76383.1 - 0.081 13.5 5.3 0.15 12.6 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) CREPT PF16566.5 EGF76383.1 - 0.22 11.7 6.4 0.11 12.6 0.9 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour eIF-1a PF01176.19 EGF76385.1 - 8.9e-18 63.9 0.0 1.3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 adh_short PF00106.25 EGF76386.1 - 9.5e-27 93.7 0.5 3.3e-12 46.3 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF76386.1 - 5.4e-13 49.1 0.6 3e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF76386.1 - 0.00017 21.5 2.3 0.004 17.1 0.2 2.4 1 1 1 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EGF76386.1 - 0.00043 19.6 0.1 0.00072 18.9 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 EGF76386.1 - 0.15 11.9 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YojJ PF10372.9 EGF76387.1 - 0.04 14.0 0.4 0.19 11.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF1194 PF06707.11 EGF76387.1 - 0.089 12.0 0.2 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) Zip PF02535.22 EGF76388.1 - 6.5e-48 163.7 28.5 6.5e-48 163.7 28.5 2.3 2 1 0 2 2 2 1 ZIP Zinc transporter Asp PF00026.23 EGF76390.1 - 5.3e-15 55.6 0.4 7.5e-14 51.9 0.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76390.1 - 0.00071 19.4 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal DUF87 PF01935.17 EGF76391.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain HBB PF06777.11 EGF76392.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain Tir_receptor_C PF07489.11 EGF76393.1 - 0.031 14.3 1.1 0.046 13.7 1.1 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF1505 PF07403.11 EGF76393.1 - 0.1 12.8 1.9 0.27 11.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) SSTK-IP PF15836.5 EGF76395.1 - 0.37 10.9 6.8 0.51 10.5 0.4 2.3 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein KRTAP PF11759.8 EGF76396.1 - 0.023 15.2 20.0 0.14 12.7 13.5 2.4 2 0 0 2 2 2 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGF76396.1 - 0.056 13.6 15.7 0.5 10.5 9.1 2.4 2 0 0 2 2 2 0 Keratin type II head GPS2_interact PF15784.5 EGF76396.1 - 0.11 13.0 0.2 0.22 12.0 0.2 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Serglycin PF04360.12 EGF76396.1 - 0.24 11.4 6.8 3 7.8 0.7 2.5 2 0 0 2 2 2 0 Serglycin DASH_Dad2 PF08654.10 EGF76396.1 - 0.56 10.7 2.3 1.9 9.0 0.4 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad2 WXG100 PF06013.12 EGF76396.1 - 1 9.7 4.1 10 6.4 0.4 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF1275 PF06912.11 EGF76397.1 - 4.2e-29 101.9 20.0 5.1e-29 101.6 20.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EGF76397.1 - 0.052 13.5 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 PIG-P DUF5105 PF17118.5 EGF76398.1 - 0.064 13.0 1.1 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) AAA_14 PF13173.6 EGF76400.1 - 0.00025 21.1 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Spc7 PF08317.11 EGF76403.1 - 0.017 14.0 0.9 0.023 13.6 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4600 PF15372.6 EGF76403.1 - 0.017 15.5 0.7 0.32 11.4 0.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) GAS PF13851.6 EGF76403.1 - 0.036 13.4 1.8 0.062 12.6 1.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 EGF76403.1 - 0.21 10.8 0.5 0.27 10.4 0.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein SCP-1 PF05483.12 EGF76403.1 - 0.46 8.4 5.0 0.57 8.1 5.0 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) TMF_DNA_bd PF12329.8 EGF76403.1 - 1.2 9.2 6.3 1.2 9.2 1.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Asp PF00026.23 EGF76405.1 - 4.7e-14 52.5 0.0 7.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76405.1 - 1.5e-06 28.1 0.3 1.3e-05 25.0 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF3490 PF11995.8 EGF76406.1 - 2.6 7.9 5.9 4.2 7.2 0.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3490) Peptidase_S41 PF03572.18 EGF76407.1 - 6e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 MxiM PF11441.8 EGF76407.1 - 0.0094 16.2 0.1 0.025 14.9 0.1 1.7 1 0 0 1 1 1 1 Pilot protein MxiM PilN PF05137.13 EGF76407.1 - 0.15 12.2 0.1 0.89 9.7 0.1 2.2 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) PPR_1 PF12854.7 EGF76407.1 - 1.9 8.3 3.8 0.43 10.3 0.4 1.7 2 0 0 2 2 2 0 PPR repeat RecG_wedge PF17191.4 EGF76408.1 - 0.021 14.4 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 RecG wedge domain Helicase_PWI PF18149.1 EGF76408.1 - 0.046 13.9 3.7 0.084 13.1 3.7 1.4 1 0 0 1 1 1 0 N-terminal helicase PWI domain SRC-1 PF08832.10 EGF76408.1 - 0.42 11.7 0.2 0.42 11.7 0.2 2.4 2 0 0 2 2 2 0 Steroid receptor coactivator Hrs_helical PF12210.8 EGF76408.1 - 0.44 11.1 7.2 0.17 12.4 4.3 1.8 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CCDC106 PF15794.5 EGF76408.1 - 7.7 6.2 17.2 0.12 12.0 3.8 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 DUF4246 PF14033.6 EGF76409.1 - 9.7e-29 100.8 0.1 1.2e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EGF76409.1 - 0.04 14.3 0.0 3.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase DUF501 PF04417.12 EGF76410.1 - 0.092 12.6 2.4 1.3 8.8 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Prominin PF05478.11 EGF76410.1 - 0.21 9.5 0.4 0.26 9.2 0.4 1.0 1 0 0 1 1 1 0 Prominin Senescence PF06911.12 EGF76411.1 - 2.5 8.4 11.5 1.7 8.9 2.6 2.7 3 0 0 3 3 3 0 Senescence-associated protein GrpE PF01025.19 EGF76411.1 - 6.4 6.4 11.6 1.3 8.7 7.3 1.9 2 0 0 2 2 2 0 GrpE Asp PF00026.23 EGF76412.1 - 0.0021 17.6 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76412.1 - 0.0085 15.9 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 EGF76413.1 - 1.9e-06 27.5 0.1 3.6e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Codanin-1_C PF15296.6 EGF76415.1 - 0.91 9.6 6.2 12 6.0 3.4 3.6 2 0 0 2 2 2 0 Codanin-1 C-terminus Ponericin PF07442.11 EGF76416.1 - 0.2 11.7 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Ponericin LRR_4 PF12799.7 EGF76417.1 - 1.2e-06 28.8 9.5 0.04 14.4 0.9 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGF76417.1 - 0.00011 21.9 5.9 4 7.7 0.0 6.5 7 0 0 7 7 7 2 Leucine Rich repeat SAM_Ste50p PF09235.10 EGF76417.1 - 0.88 9.9 3.4 7.9 6.8 0.0 3.2 1 1 2 3 3 3 0 Ste50p, sterile alpha motif Rad60-SLD_2 PF13881.6 EGF76418.1 - 6.8e-15 55.1 0.0 7.4e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGF76418.1 - 0.0021 17.8 0.0 0.0065 16.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DED PF01335.21 EGF76419.1 - 6 7.3 8.6 22 5.4 0.3 3.5 3 1 0 4 4 4 0 Death effector domain MDMPI_C PF07398.11 EGF76420.1 - 0.036 14.9 0.5 0.05 14.5 0.5 1.2 1 0 0 1 1 1 0 MDMPI C-terminal domain Fungus-induced PF10917.8 EGF76420.1 - 0.098 13.0 3.2 0.099 13.0 0.0 2.3 2 1 1 3 3 3 0 Fungus-induced protein YjbE PF11106.8 EGF76420.1 - 0.55 10.5 7.8 0.31 11.3 3.4 2.0 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Fungus-induced PF10917.8 EGF76421.1 - 0.013 15.8 1.0 0.092 13.1 0.0 2.2 1 1 1 2 2 2 0 Fungus-induced protein HEAT_2 PF13646.6 EGF76422.1 - 0.036 14.4 0.2 3 8.3 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats PAF-AH_p_II PF03403.13 EGF76423.1 - 3.3e-65 220.0 0.0 4.3e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGF76423.1 - 3.5e-09 36.0 0.0 3.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGF76423.1 - 1.2e-05 24.8 0.0 0.058 12.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EGF76423.1 - 2.3e-05 23.6 0.1 0.0003 19.9 0.1 2.0 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S9 PF00326.21 EGF76423.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGF76423.1 - 0.0031 17.1 0.0 0.0071 15.9 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EGF76423.1 - 0.043 13.6 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EGF76423.1 - 0.075 13.6 0.2 0.26 11.8 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Gtr1_RagA PF04670.12 EGF76424.1 - 6.7e-100 333.2 0.3 8e-100 333.0 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EGF76424.1 - 9.3e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF76424.1 - 1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF76424.1 - 1.2e-06 28.1 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF76424.1 - 0.00056 19.5 0.0 0.0009 18.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ILEI PF15711.5 EGF76424.1 - 0.066 13.7 0.1 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 Interleukin-like EMT inducer DUF1202 PF06717.11 EGF76424.1 - 0.23 10.8 0.7 0.36 10.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) UQ_con PF00179.26 EGF76425.1 - 1.7e-49 167.1 0.0 1.9e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGF76425.1 - 0.074 13.3 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain ABC_tran PF00005.27 EGF76426.1 - 2.4e-48 164.1 0.3 8.2e-31 107.3 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGF76426.1 - 6.7e-39 134.2 29.7 4.7e-27 95.3 14.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGF76426.1 - 1.7e-12 47.3 4.8 0.0025 17.3 0.8 4.4 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF76426.1 - 4.3e-07 30.0 0.3 0.02 15.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGF76426.1 - 1.3e-06 28.9 0.1 0.014 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGF76426.1 - 7.8e-06 25.5 0.8 0.15 11.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF76426.1 - 9.7e-05 22.3 5.6 0.062 13.1 0.5 4.2 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 EGF76426.1 - 0.00012 21.5 0.3 0.23 10.8 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.22 EGF76426.1 - 0.00018 21.9 0.4 1.8 9.0 0.0 3.3 3 0 0 3 3 3 2 RNA helicase NB-ARC PF00931.22 EGF76426.1 - 0.00066 18.9 0.3 0.3 10.2 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EGF76426.1 - 0.00072 19.8 0.2 0.64 10.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 EGF76426.1 - 0.0012 19.0 12.0 0.0049 17.0 0.2 3.4 2 1 1 3 3 3 1 Helicase HerA, central domain ATP_bind_1 PF03029.17 EGF76426.1 - 0.0018 18.1 1.3 0.61 9.8 0.1 2.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGF76426.1 - 0.002 17.7 0.1 0.91 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGF76426.1 - 0.0026 17.7 0.4 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Ploopntkinase3 PF18751.1 EGF76426.1 - 0.0036 17.2 0.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 EGF76426.1 - 0.0047 16.7 3.2 0.19 11.5 0.1 3.0 3 1 0 3 3 2 1 AAA domain AAA_25 PF13481.6 EGF76426.1 - 0.0057 16.3 0.0 3.6 7.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain TrwB_AAD_bind PF10412.9 EGF76426.1 - 0.0057 15.6 0.3 2.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EGF76426.1 - 0.0094 15.6 0.3 4.7 6.8 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EGF76426.1 - 0.012 14.7 0.1 2.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EGF76426.1 - 0.013 15.5 2.4 1.8 8.4 0.1 3.1 3 0 0 3 3 3 0 NACHT domain Dynamin_N PF00350.23 EGF76426.1 - 0.014 15.5 9.4 0.12 12.4 0.8 3.4 3 0 0 3 3 3 0 Dynamin family Zeta_toxin PF06414.12 EGF76426.1 - 0.014 14.6 0.3 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EGF76426.1 - 0.026 14.2 0.1 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGF76426.1 - 0.028 14.6 0.3 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EGF76426.1 - 0.063 13.8 1.8 3.6 8.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.12 EGF76426.1 - 0.069 12.6 0.3 4.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DUF815 PF05673.13 EGF76426.1 - 0.071 12.3 0.4 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 EGF76426.1 - 0.083 12.4 0.1 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGF76426.1 - 0.17 12.0 0.4 14 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EGF76426.1 - 0.18 11.7 0.3 9.7 6.1 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EGF76426.1 - 0.2 12.2 0.4 18 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGF76426.1 - 0.24 11.1 3.5 10 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain PMP1_2 PF08114.11 EGF76426.1 - 0.25 11.1 7.4 0.018 14.8 1.4 2.3 2 0 0 2 2 1 0 ATPase proteolipid family Peptidase_S9_N PF02897.15 EGF76427.1 - 1.1e-112 376.9 1.4 1.4e-112 376.6 1.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGF76427.1 - 2.9e-59 200.1 0.4 5.5e-59 199.2 0.4 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGF76427.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DER1 PF04511.15 EGF76428.1 - 4.5e-43 147.4 11.6 5.3e-43 147.2 11.6 1.0 1 0 0 1 1 1 1 Der1-like family DUF4436 PF14494.6 EGF76430.1 - 1.9e-30 106.0 2.0 2.8e-30 105.5 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) ABC2_membrane_5 PF13346.6 EGF76430.1 - 0.0024 17.5 3.3 0.006 16.2 3.3 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_6 PF12774.7 EGF76431.1 - 4.1e-127 423.7 1.0 5.9e-126 419.9 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF76431.1 - 2.1e-99 333.3 9.3 2.1e-99 333.3 9.3 4.7 6 0 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGF76431.1 - 2.8e-72 242.4 3.6 2.8e-72 242.4 3.6 2.8 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGF76431.1 - 4.1e-37 127.9 1.9 8.5e-34 117.1 0.0 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 EGF76431.1 - 2.8e-36 124.2 0.0 1.1e-34 119.0 0.0 3.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain DHC_N1 PF08385.12 EGF76431.1 - 5e-35 121.2 3.2 5e-35 121.2 3.2 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_lid_11 PF18198.1 EGF76431.1 - 7.2e-33 113.7 0.0 2.1e-32 112.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGF76431.1 - 2.5e-32 111.8 0.0 3.1e-20 72.6 0.0 4.5 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) Dynein_C PF18199.1 EGF76431.1 - 1.9e-30 106.1 0.3 1.9e-30 106.1 0.3 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGF76431.1 - 1.4e-28 99.7 0.2 7.4e-24 84.3 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 EGF76431.1 - 1e-25 90.5 5.5 2.5e-25 89.2 5.5 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 EGF76431.1 - 2.7e-10 40.9 0.0 0.0029 18.0 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGF76431.1 - 3e-09 37.2 0.7 0.044 14.1 0.0 5.4 4 0 0 4 4 4 2 AAA domain ABC_tran PF00005.27 EGF76431.1 - 1.1e-06 29.2 0.8 0.015 15.8 0.0 4.4 4 0 0 4 4 3 2 ABC transporter AAA PF00004.29 EGF76431.1 - 6.3e-06 26.6 0.9 0.66 10.4 0.0 5.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGF76431.1 - 1.8e-05 24.5 0.1 0.031 14.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EGF76431.1 - 8.9e-05 22.4 6.8 0.0059 16.5 0.0 3.9 4 0 0 4 4 2 2 RsgA GTPase AAA_24 PF13479.6 EGF76431.1 - 0.00034 20.4 0.3 0.25 11.0 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.6 EGF76431.1 - 0.00043 20.8 0.0 0.22 12.1 0.0 3.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGF76431.1 - 0.00093 18.9 0.0 0.14 11.9 0.0 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EGF76431.1 - 0.0012 18.5 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Guanylate_kin PF00625.21 EGF76431.1 - 0.0015 18.3 0.2 0.13 12.0 0.0 3.0 2 0 0 2 2 2 1 Guanylate kinase AAA_28 PF13521.6 EGF76431.1 - 0.0022 18.2 0.0 0.16 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 EGF76431.1 - 0.0026 17.0 0.2 2.8 7.0 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF815) TMF_DNA_bd PF12329.8 EGF76431.1 - 0.0058 16.6 1.4 0.0058 16.6 1.4 6.9 5 1 1 6 6 3 1 TATA element modulatory factor 1 DNA binding AAA_33 PF13671.6 EGF76431.1 - 0.013 15.7 4.8 0.26 11.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 EGF76431.1 - 0.017 14.7 0.0 2.6 7.6 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGF76431.1 - 0.025 13.8 0.0 1.5 8.0 0.0 3.0 2 0 0 2 2 2 0 Zeta toxin FlaC_arch PF05377.11 EGF76431.1 - 0.03 14.7 2.2 0.55 10.7 0.0 4.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) AAA_lid_1 PF17857.1 EGF76431.1 - 0.05 13.8 0.2 0.3 11.3 0.2 2.4 1 0 0 1 1 1 0 AAA+ lid domain RNA_helicase PF00910.22 EGF76431.1 - 0.072 13.5 0.1 3.9 7.9 0.0 3.3 3 0 0 3 3 2 0 RNA helicase Mg_chelatase PF01078.21 EGF76431.1 - 0.079 12.3 0.1 9.6 5.5 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EGF76431.1 - 0.77 10.2 0.0 0.77 10.2 0.0 7.5 7 2 0 7 7 6 0 AAA domain Cytidylate_kin PF02224.18 EGF76431.1 - 3.3 7.4 5.9 7.3 6.3 0.0 3.7 4 0 0 4 4 3 0 Cytidylate kinase MbeB_N PF04837.12 EGF76431.1 - 5 7.5 10.1 9 6.7 1.4 4.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region DNApol_Exo PF18136.1 EGF76432.1 - 1e-88 297.2 0.0 1.5e-88 296.6 0.0 1.2 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EGF76432.1 - 6.6e-47 160.4 0.0 1e-46 159.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EGF76432.1 - 0.0078 15.9 0.0 0.17 11.6 0.0 2.6 1 1 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 EGF76433.1 - 3e-53 180.9 0.0 3.9e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76433.1 - 1.9e-22 79.8 0.0 2.6e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGF76433.1 - 0.0083 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGF76433.1 - 0.0095 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fmp27_WPPW PF10359.9 EGF76433.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PCI PF01399.27 EGF76434.1 - 1.5e-05 25.5 0.6 4.8e-05 23.8 0.3 2.0 2 0 0 2 2 2 1 PCI domain Spike_rec_bind PF09408.10 EGF76434.1 - 0.026 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Spike receptor binding domain Cyclin_N PF00134.23 EGF76435.1 - 2.6e-07 30.4 0.1 8.9e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGF76435.1 - 0.00042 20.7 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 EGF76435.1 - 0.0012 18.8 0.1 0.0098 15.9 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EGF76435.1 - 0.0019 18.3 0.1 0.17 11.9 0.0 2.3 2 1 0 2 2 2 2 Cyclin, C-terminal domain CREPT PF16566.5 EGF76436.1 - 0.013 15.7 0.6 0.023 14.9 0.6 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Stevor PF17410.2 EGF76436.1 - 0.016 14.7 0.3 0.028 14.0 0.3 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2408 PF10303.9 EGF76436.1 - 0.026 15.1 1.4 0.052 14.1 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Tom37_C PF11801.8 EGF76436.1 - 0.046 13.7 0.3 0.072 13.1 0.3 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain POP1 PF06978.11 EGF76437.1 - 0.032 14.2 0.4 0.041 13.9 0.4 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 FlaC_arch PF05377.11 EGF76437.1 - 0.26 11.7 0.2 0.26 11.7 0.2 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pyr_redox_2 PF07992.14 EGF76438.1 - 2.9e-60 204.0 1.1 3.9e-60 203.6 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGF76438.1 - 3.9e-32 110.8 0.5 3e-31 107.9 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGF76438.1 - 1.5e-17 63.9 3.6 3.5e-15 56.3 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGF76438.1 - 6.3e-12 45.4 4.4 7.1e-12 45.2 2.6 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF76438.1 - 4.9e-05 22.9 0.1 6.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EGF76438.1 - 0.00016 21.1 0.3 0.018 14.4 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGF76438.1 - 0.00019 20.8 3.0 0.23 10.7 0.9 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGF76438.1 - 0.00068 19.6 2.7 0.0065 16.4 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EGF76438.1 - 0.0012 18.1 0.0 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EGF76438.1 - 0.0014 17.8 7.3 0.029 13.4 4.5 3.1 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EGF76438.1 - 0.0035 17.7 0.4 3.3 8.2 0.0 3.1 3 1 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EGF76438.1 - 0.0036 16.4 2.1 0.0076 15.4 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain LktC PF06261.11 EGF76438.1 - 0.038 13.9 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC HI0933_like PF03486.14 EGF76438.1 - 0.055 12.2 5.0 0.061 12.0 0.5 2.5 3 1 0 3 3 3 0 HI0933-like protein XdhC_C PF13478.6 EGF76438.1 - 0.064 13.8 0.1 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 EGF76438.1 - 0.11 12.7 5.0 0.062 13.5 1.5 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AAA_19 PF13245.6 EGF76438.1 - 0.13 12.6 0.0 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thi4 PF01946.17 EGF76438.1 - 0.18 11.0 1.3 0.26 10.5 0.3 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EGF76438.1 - 0.18 11.0 0.9 13 4.9 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain MeaB PF03308.16 EGF76439.1 - 0.0097 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGF76439.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RHSP PF07999.11 EGF76439.1 - 0.034 13.0 0.1 0.49 9.1 0.0 2.2 2 1 0 2 2 2 0 Retrotransposon hot spot protein ATPase PF06745.13 EGF76439.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EGF76439.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NMT1 PF09084.11 EGF76442.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like IFT57 PF10498.9 EGF76443.1 - 0.022 13.8 0.7 0.028 13.4 0.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3584 PF12128.8 EGF76443.1 - 0.038 11.5 0.8 0.047 11.2 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med21 PF11221.8 EGF76443.1 - 1.1 9.5 5.3 4.7 7.5 5.3 1.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex IstB_IS21 PF01695.17 EGF76444.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Actin PF00022.19 EGF76446.1 - 4e-115 384.7 0.0 3.5e-114 381.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGF76446.1 - 0.031 13.1 0.0 0.11 11.3 0.0 1.7 1 1 0 1 1 1 0 MreB/Mbl protein Nop53 PF07767.11 EGF76447.1 - 1.5e-67 228.7 18.1 1.8e-67 228.5 18.1 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 EGF76447.1 - 1.9 6.7 20.8 0.67 8.2 18.4 1.4 1 1 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 EGF76448.1 - 2.8e-07 30.8 0.8 0.0077 16.6 0.0 3.2 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGF76448.1 - 3.4e-07 30.0 0.2 9.9e-07 28.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGF76448.1 - 6.2e-07 29.0 3.4 0.00029 20.6 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EGF76448.1 - 0.0025 18.1 0.7 16 6.5 0.0 4.5 4 1 0 4 4 4 1 Leucine Rich Repeat F-box_4 PF15966.5 EGF76448.1 - 0.011 15.6 1.8 0.011 15.6 0.1 2.0 2 0 0 2 2 2 0 F-box F-box PF00646.33 EGF76448.1 - 0.037 13.9 0.3 0.037 13.9 0.3 2.3 2 0 0 2 2 2 0 F-box domain PGM_PMM_I PF02878.16 EGF76449.1 - 4.5e-19 68.5 0.3 1.9e-09 37.4 0.1 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGF76449.1 - 7.2e-09 35.7 0.0 9.8e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EGF76449.1 - 0.00051 20.2 0.3 0.0011 19.2 0.3 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGF76449.1 - 0.047 14.3 4.3 3.3 8.4 0.8 4.5 4 1 0 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II TBCC PF07986.12 EGF76451.1 - 2e-12 46.9 6.3 1.3e-10 41.0 2.7 3.5 3 1 0 3 3 3 2 Tubulin binding cofactor C CAP_C PF08603.11 EGF76451.1 - 9.6e-05 22.0 1.0 0.00021 20.9 1.0 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal NUDIX PF00293.28 EGF76452.1 - 6.5e-07 29.4 0.0 1.9e-05 24.7 0.0 2.5 1 1 0 1 1 1 1 NUDIX domain Ku PF02735.16 EGF76454.1 - 2.1e-35 122.3 0.0 3.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGF76454.1 - 1.1e-28 100.6 0.2 2.4e-28 99.4 0.1 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGF76454.1 - 6e-10 39.7 0.0 1.3e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm TauD PF02668.16 EGF76455.1 - 7.4e-47 160.4 0.2 9.6e-47 160.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGF76455.1 - 2.4e-07 31.3 0.1 1.1e-06 29.2 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGF76455.1 - 3.3e-06 26.4 0.0 1.4e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 CsiD NUFIP1 PF10453.9 EGF76457.1 - 4.9e-13 48.7 6.0 4.9e-13 48.7 6.0 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RTX_C PF08339.10 EGF76457.1 - 0.36 10.9 12.5 0.25 11.4 5.2 2.4 2 0 0 2 2 2 0 RTX C-terminal domain zf-CCCH_4 PF18044.1 EGF76457.1 - 1.1 9.1 6.2 1.9 8.4 6.2 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger DAP3 PF10236.9 EGF76458.1 - 5.2e-38 131.0 0.1 1e-37 130.0 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EGF76458.1 - 0.0055 17.1 0.0 0.014 15.8 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGF76458.1 - 0.092 12.8 0.1 0.97 9.5 0.0 2.7 1 1 0 1 1 1 0 AAA domain Homeobox_KN PF05920.11 EGF76459.1 - 4.6e-11 42.4 0.3 1e-10 41.3 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGF76459.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain Big_3_3 PF13750.6 EGF76459.1 - 0.051 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Vta1 PF04652.16 EGF76460.1 - 1.3e-49 167.8 5.3 1.4e-49 167.8 3.5 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EGF76460.1 - 2.8e-17 62.1 1.0 8.6e-17 60.6 1.0 1.9 1 0 0 1 1 1 1 Vta1 C-terminal domain Peptidase_C48 PF02902.19 EGF76461.1 - 3.3e-46 157.8 1.5 4.1e-46 157.6 1.5 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 EGF76461.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 1 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Nucleoporin_N PF08801.11 EGF76462.1 - 2e-52 178.4 0.2 3.5e-52 177.6 0.2 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGF76462.1 - 4.4e-30 105.0 5.9 1e-29 103.8 5.8 1.6 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF3591 PF12157.8 EGF76463.1 - 2.4e-162 540.6 0.1 3.2e-162 540.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 EGF76463.1 - 2.6e-13 49.8 0.1 1.4e-12 47.5 0.1 2.4 2 0 0 2 2 2 1 Bromodomain TBP-binding PF09247.11 EGF76463.1 - 2.4e-07 30.9 0.1 6.9e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 TATA box-binding protein binding TFIIF_beta PF02270.15 EGF76463.1 - 0.065 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain TPR_2 PF07719.17 EGF76464.1 - 1.1e-10 40.8 0.0 2.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF76464.1 - 1.6e-09 37.1 0.1 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76464.1 - 1.1e-07 31.4 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF76464.1 - 8.6e-07 29.1 0.0 1.8e-06 28.1 0.0 1.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGF76464.1 - 1.7e-06 27.6 0.2 0.00059 19.5 0.0 2.2 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 EGF76464.1 - 2.8e-06 27.7 0.0 4.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF76464.1 - 1.5e-05 25.4 0.0 0.016 16.0 0.0 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76464.1 - 0.00047 20.0 0.0 0.97 9.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF76464.1 - 0.0036 17.6 0.4 0.35 11.3 0.1 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF76464.1 - 0.0094 16.2 0.0 0.059 13.7 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat PaRep2b PF07775.11 EGF76464.1 - 0.025 13.1 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 PaRep2b protein TPR_20 PF14561.6 EGF76464.1 - 0.039 14.3 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGF76464.1 - 0.04 13.9 0.0 0.087 12.8 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SesA PF17107.5 EGF76465.1 - 0.24 11.6 11.0 0.021 15.0 5.0 2.3 2 2 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FlaC_arch PF05377.11 EGF76465.1 - 1.2 9.6 4.5 27 5.2 0.6 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_L50 PF10501.9 EGF76466.1 - 6.8e-05 23.0 0.1 9.4e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S CBF PF03914.17 EGF76467.1 - 1.2e-32 113.2 1.2 2.9e-32 112.0 0.2 2.1 2 0 0 2 2 2 1 CBF/Mak21 family Fip1 PF05182.13 EGF76468.1 - 1e-24 85.8 4.2 2.2e-24 84.7 4.2 1.6 1 0 0 1 1 1 1 Fip1 motif GCIP PF13324.6 EGF76470.1 - 2.6e-20 73.1 3.2 2.6e-20 73.1 3.2 1.9 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting UCH PF00443.29 EGF76471.1 - 2.6e-49 168.0 0.3 5e-49 167.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF76471.1 - 3.3e-25 89.4 1.3 3.3e-25 89.4 1.3 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_68 PF02435.16 EGF76471.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Levansucrase/Invertase Pkinase PF00069.25 EGF76472.1 - 1.8e-62 211.1 0.0 2.3e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76472.1 - 6.4e-45 153.5 0.0 8.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF76472.1 - 0.00056 18.8 0.0 0.00068 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF76472.1 - 0.00085 18.7 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGF76472.1 - 0.0055 15.8 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGF76472.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KLRAQ PF10205.9 EGF76473.1 - 9.9e-05 22.5 2.7 9.9e-05 22.5 2.7 2.2 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein Activator_LAG-3 PF11498.8 EGF76473.1 - 7.3 5.4 8.2 9.7 5.0 8.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1992 PF09350.10 EGF76475.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) Peptidase_C97 PF05903.14 EGF76478.1 - 0.00038 20.3 0.0 0.0008 19.3 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain Nucleoporin_C PF03177.14 EGF76480.1 - 1.4e-52 179.2 11.6 1.3e-36 126.6 4.5 2.1 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EGF76480.1 - 1.1e-11 44.2 0.0 2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Nup133 N terminal like Ribosomal_L37 PF08561.10 EGF76481.1 - 3.4e-20 72.7 1.4 6.5e-20 71.9 1.4 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 PIG-P PF08510.12 EGF76482.1 - 2.4e-36 124.3 1.2 2.9e-36 124.0 1.2 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EGF76482.1 - 0.00055 20.2 4.1 0.00092 19.5 4.1 1.3 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) RRM_1 PF00076.22 EGF76483.1 - 8e-16 57.6 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.18 EGF76484.1 - 1e-80 269.7 0.4 1.3e-80 269.3 0.4 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGF76484.1 - 8.6e-21 73.3 3.7 8.6e-21 73.3 3.7 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGF76484.1 - 0.019 15.4 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ANAPC3 PF12895.7 EGF76485.1 - 1.6e-17 63.5 16.6 5.1e-07 29.8 0.1 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGF76485.1 - 9.1e-15 54.9 0.7 4e-05 24.0 0.1 5.6 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76485.1 - 3.3e-09 36.2 16.0 0.24 11.6 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGF76485.1 - 3e-07 30.6 3.6 3.6 8.4 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF76485.1 - 6.3e-05 22.6 14.3 0.97 9.4 0.1 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF76485.1 - 0.0001 22.5 9.1 1.2 9.5 0.1 6.1 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF76485.1 - 0.00032 21.3 0.0 0.53 11.0 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF76485.1 - 0.00033 21.2 0.3 13 6.9 0.0 5.8 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF76485.1 - 0.00033 20.7 0.0 1.3 9.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76485.1 - 0.00046 20.0 3.7 0.14 12.2 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76485.1 - 0.02 15.0 12.9 6 7.3 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 EGF76485.1 - 0.049 13.9 1.1 7 7.1 0.0 4.7 5 0 0 5 5 4 0 PPR repeat TPR_17 PF13431.6 EGF76485.1 - 0.85 10.1 4.3 15 6.3 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Topoisom_bac PF01131.20 EGF76486.1 - 9.5e-106 354.2 0.0 1.2e-105 354.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGF76486.1 - 4.1e-17 62.3 0.0 8.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain PP-binding PF00550.25 EGF76487.1 - 1.3e-12 47.9 1.1 1.5e-12 47.7 1.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site TFA2_Winged_2 PF18121.1 EGF76488.1 - 7.7e-19 67.1 0.4 2.2e-18 65.7 0.2 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EGF76488.1 - 1.5e-09 38.0 0.8 9.1e-09 35.5 0.0 2.4 2 1 1 3 3 3 1 TFIIE beta subunit core domain DUF1919 PF08942.10 EGF76488.1 - 0.04 13.4 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) Ribosomal_S19e PF01090.19 EGF76489.1 - 4.4e-56 188.4 0.0 5e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SIL1 PF16782.5 EGF76490.1 - 7e-07 28.8 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 EGF76490.1 - 0.012 16.0 0.1 0.042 14.2 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats Arm PF00514.23 EGF76490.1 - 0.12 12.5 0.1 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PET117 PF15786.5 EGF76491.1 - 1.3e-22 79.8 0.3 1.6e-22 79.5 0.3 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial PNP_UDP_1 PF01048.20 EGF76492.1 - 4.9e-30 104.5 0.1 6e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily ribosomal_L24 PF17136.4 EGF76493.1 - 3.8e-11 43.2 0.0 6.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EGF76493.1 - 0.0098 15.8 4.1 0.025 14.6 4.1 1.7 1 1 0 1 1 1 1 KOW motif RRM_1 PF00076.22 EGF76494.1 - 6.9e-29 99.5 0.9 5.6e-14 51.7 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF76494.1 - 1.4e-05 24.8 0.0 0.068 13.0 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGF76494.1 - 0.012 15.7 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Transformer PF06495.11 EGF76494.1 - 0.039 14.1 20.6 0.066 13.3 20.6 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein Nup35_RRM_2 PF14605.6 EGF76494.1 - 0.079 13.0 0.1 0.99 9.5 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3824 PF12868.7 EGF76494.1 - 0.64 10.7 11.8 0.079 13.6 7.3 1.7 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) SH3_1 PF00018.28 EGF76495.1 - 5.2e-19 67.6 0.5 1.2e-08 34.4 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SAM_2 PF07647.17 EGF76495.1 - 5.6e-15 55.2 0.1 1.2e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EGF76495.1 - 6e-12 45.2 0.1 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.30 EGF76495.1 - 5.7e-11 42.7 0.2 1.3e-10 41.6 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EGF76495.1 - 2.6e-10 39.8 0.2 1.5e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 EGF76495.1 - 1.4e-09 38.4 0.1 1.3e-08 35.3 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EGF76495.1 - 0.003 17.5 0.4 0.0099 15.8 0.4 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) VHP PF02209.19 EGF76495.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Villin headpiece domain SlyX PF04102.12 EGF76495.1 - 0.073 13.7 0.3 0.23 12.1 0.3 1.9 1 0 0 1 1 1 0 SlyX SH3_10 PF17902.1 EGF76495.1 - 0.096 12.8 0.0 0.54 10.4 0.0 2.3 1 0 0 1 1 1 0 SH3 domain Pkinase PF00069.25 EGF76496.1 - 6.9e-56 189.5 0.4 1.1e-55 188.9 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76496.1 - 8.6e-42 143.2 0.1 1.2e-41 142.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 EGF76496.1 - 0.00044 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 EGF76496.1 - 0.031 13.1 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase GH114_assoc PF14741.6 EGF76496.1 - 0.052 13.8 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain DUF3450 PF11932.8 EGF76497.1 - 0.042 13.2 13.4 0.021 14.2 10.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Leu_zip PF15294.6 EGF76497.1 - 0.28 10.6 16.5 0.45 10.0 16.5 1.3 1 0 0 1 1 1 0 Leucine zipper DUF262 PF03235.14 EGF76497.1 - 2.9 8.0 12.6 0.54 10.4 8.8 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF262 V_ATPase_I PF01496.19 EGF76497.1 - 5.8 4.7 10.8 6.2 4.6 10.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.13 EGF76497.1 - 7.5 6.5 11.7 3.7 7.5 2.7 3.0 2 1 0 2 2 2 0 Sec20 RNA_pol_Rpb1_5 PF04998.17 EGF76498.1 - 9.2e-81 271.2 0.5 1.5e-80 270.4 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EGF76498.1 - 1.1e-80 271.3 1.2 1.9e-80 270.5 1.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGF76498.1 - 2.9e-75 252.1 0.0 5.7e-75 251.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGF76498.1 - 8.9e-39 132.9 0.0 4.8e-38 130.6 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGF76498.1 - 1.5e-31 108.6 0.5 6e-31 106.6 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 EGF76498.1 - 0.18 12.1 3.1 0.64 10.4 3.1 2.0 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HEAT PF02985.22 EGF76499.1 - 5.4e-08 32.4 0.0 0.026 14.7 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EGF76499.1 - 2.6e-05 24.5 0.0 4.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 EGF76499.1 - 6.4e-05 23.1 0.1 9.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EGF76499.1 - 0.00047 19.4 0.2 0.00055 19.2 0.2 1.1 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 EGF76499.1 - 0.016 15.5 0.1 5.4 7.4 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 EGF76499.1 - 0.023 13.3 0.2 0.029 13.0 0.2 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGF76499.1 - 0.024 15.2 0.2 0.063 13.9 0.1 1.7 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGF76499.1 - 0.13 12.8 0.0 0.7 10.5 0.0 2.1 2 0 0 2 2 2 0 HEAT-like repeat SBF_like PF13593.6 EGF76501.1 - 1.2e-63 215.4 21.7 1.4e-63 215.1 21.7 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) WD40 PF00400.32 EGF76502.1 - 1.2e-35 120.9 26.3 1.9e-07 31.6 0.5 8.2 7 1 1 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76502.1 - 2.3e-18 66.3 0.8 0.0013 19.0 0.0 5.9 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF76502.1 - 9.3e-12 44.9 0.0 0.0029 17.0 0.0 3.7 3 1 1 4 4 4 3 WD40-like domain eIF2A PF08662.11 EGF76502.1 - 7.2e-08 32.5 0.0 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 EGF76502.1 - 5.1e-06 26.8 6.0 0.66 10.5 0.1 5.6 6 0 0 6 6 6 2 PQQ-like domain Ge1_WD40 PF16529.5 EGF76502.1 - 0.00011 21.3 2.0 0.82 8.6 0.1 3.7 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EGF76502.1 - 0.0052 16.4 0.1 0.067 12.8 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.12 EGF76502.1 - 0.068 13.1 1.2 50 4.0 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Plus-3 PF03126.18 EGF76503.1 - 1.3e-29 102.8 0.0 4.5e-29 101.2 0.0 2.0 1 0 0 1 1 1 1 Plus-3 domain ChapFlgA PF13144.6 EGF76503.1 - 0.075 13.1 1.2 0.17 11.9 1.2 1.6 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation TRM PF02005.16 EGF76504.1 - 7e-118 394.1 0.0 8.5e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EGF76504.1 - 1.5e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EGF76504.1 - 0.0054 16.4 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 EGF76504.1 - 0.18 11.2 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA-synt_2 PF00152.20 EGF76505.1 - 9.3e-79 264.7 0.1 1.2e-78 264.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGF76505.1 - 5.5e-08 32.7 0.1 1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ABC_membrane_2 PF06472.15 EGF76506.1 - 9.1e-93 310.5 2.0 1.2e-92 310.1 2.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGF76506.1 - 8.7e-15 55.4 0.0 1.8e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF76506.1 - 2.4e-05 24.3 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF76506.1 - 0.00046 20.7 0.1 0.0055 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGF76506.1 - 0.0027 17.4 0.2 0.009 15.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGF76506.1 - 0.014 14.8 0.0 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 EGF76506.1 - 0.028 13.8 0.1 0.89 8.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_27 PF13514.6 EGF76506.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EGF76506.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AIM24 PF01987.17 EGF76507.1 - 4.2e-42 144.2 0.8 5.2e-42 143.9 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF1295 PF06966.12 EGF76508.1 - 2.3e-50 171.3 4.5 3.1e-50 170.9 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGF76508.1 - 4.7e-05 23.4 0.7 4.7e-05 23.4 0.7 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGF76508.1 - 0.0051 17.2 0.5 0.0051 17.2 0.5 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EGF76508.1 - 0.0063 16.9 0.0 0.0063 16.9 0.0 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MutS_V PF00488.21 EGF76509.1 - 4e-83 278.1 0.3 8.2e-83 277.1 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGF76509.1 - 4.2e-34 118.4 0.7 4.2e-34 118.4 0.7 2.4 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 EGF76509.1 - 1.6e-16 60.4 0.5 3.8e-16 59.2 0.5 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGF76509.1 - 3.4e-16 59.8 0.2 5.5e-15 55.9 0.0 2.7 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 EGF76509.1 - 1.9e-11 44.2 0.0 4.6e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 EGF76509.1 - 0.059 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4246 PF14033.6 EGF76510.1 - 5.3e-84 282.9 0.6 5.9e-84 282.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Opacity PF02462.15 EGF76510.1 - 0.069 13.3 0.1 5.7 7.1 0.0 2.1 1 1 1 2 2 2 0 Opacity family porin protein BMFP PF04380.13 EGF76511.1 - 0.021 15.3 1.4 0.54 10.8 0.3 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity DUF5089 PF17002.5 EGF76511.1 - 0.023 14.6 0.7 0.035 14.0 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) DUF1664 PF07889.12 EGF76511.1 - 0.07 13.2 0.2 0.17 11.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) INT_SG_DDX_CT_C PF15300.6 EGF76511.1 - 0.089 12.6 0.9 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus zf-BED PF02892.15 EGF76513.1 - 2.4e-05 24.3 0.0 4.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 BED zinc finger UxaC PF02614.14 EGF76513.1 - 0.0052 15.7 0.0 0.0063 15.4 0.0 1.3 1 0 0 1 1 1 1 Glucuronate isomerase Dimer_Tnp_hAT PF05699.14 EGF76514.1 - 3.1e-19 68.6 0.2 3.3e-19 68.5 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ras PF00071.22 EGF76515.1 - 3.1e-54 182.9 0.0 3.6e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF76515.1 - 3.5e-21 75.6 0.0 5.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF76515.1 - 1e-07 31.6 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF76515.1 - 0.0029 17.2 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGF76515.1 - 0.14 11.9 0.4 3.8 7.3 0.0 2.9 2 2 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L21e PF01157.18 EGF76516.1 - 1.9e-45 152.8 3.8 1.9e-45 152.8 3.8 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e PRKCSH PF07915.13 EGF76517.1 - 1e-08 36.0 1.0 1e-08 36.0 1.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGF76517.1 - 0.0099 15.6 0.4 0.023 14.4 0.4 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CENP-F_leu_zip PF10473.9 EGF76519.1 - 0.028 14.4 42.1 0.038 14.0 13.4 4.4 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 EGF76519.1 - 0.076 10.9 22.0 0.062 11.2 9.8 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM184 PF15665.5 EGF76519.1 - 0.49 10.1 33.8 0.011 15.5 18.3 2.6 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Laminin_II PF06009.12 EGF76519.1 - 1.2 9.1 24.8 0.16 11.9 8.6 3.9 3 1 1 4 4 4 0 Laminin Domain II BORCS6 PF10157.9 EGF76519.1 - 1.2 9.3 9.2 0.64 10.2 0.6 3.5 3 1 1 4 4 4 0 BLOC-1-related complex sub-unit 6 DUF4407 PF14362.6 EGF76519.1 - 2.1 7.6 18.3 0.097 12.0 3.4 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Pantoate_ligase PF02569.15 EGF76519.1 - 2.9 7.0 8.2 0.28 10.4 1.3 2.2 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase DUF948 PF06103.11 EGF76519.1 - 3.3 8.0 17.2 1.2 9.4 4.0 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HIP1_clath_bdg PF16515.5 EGF76519.1 - 4.8 7.9 33.3 4.4 8.0 7.3 4.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF489 PF04356.12 EGF76519.1 - 5.2 7.0 14.5 2.4 8.1 1.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF489) POT1PC PF16686.5 EGF76520.1 - 1.6e-09 37.8 0.1 0.00046 20.1 0.0 2.5 2 0 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EGF76520.1 - 3.2e-07 30.3 0.0 6.4e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 NPV_P10 PF05531.12 EGF76520.1 - 0.11 13.0 0.2 0.31 11.5 0.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein zinc_ribbon_5 PF13719.6 EGF76520.1 - 0.11 12.2 0.6 0.23 11.2 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Opy2 PF09463.10 EGF76520.1 - 0.63 10.4 5.7 6.6 7.1 0.0 2.9 3 0 0 3 3 3 0 Opy2 protein PhnA_Zn_Ribbon PF08274.12 EGF76520.1 - 1.6 8.7 4.0 3.2 7.8 4.0 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon MMS19_N PF14500.6 EGF76522.1 - 1e-80 271.1 9.2 6.2e-74 248.9 0.2 4.3 3 1 1 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EGF76522.1 - 9e-61 206.3 23.7 2.7e-56 191.5 20.2 3.4 2 2 0 2 2 2 2 RNAPII transcription regulator C-terminal DUF3437 PF11919.8 EGF76522.1 - 0.00095 19.0 0.9 4.7 7.2 0.1 4.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3437) HEAT PF02985.22 EGF76522.1 - 0.00096 19.2 6.1 15 6.2 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat ParcG PF10274.9 EGF76522.1 - 0.0015 18.7 0.5 0.0015 18.7 0.5 3.3 4 0 0 4 4 4 1 Parkin co-regulated protein HEAT_2 PF13646.6 EGF76522.1 - 0.0031 17.9 3.9 0.74 10.2 0.0 4.8 5 0 0 5 5 5 1 HEAT repeats RTP1_C1 PF10363.9 EGF76522.1 - 0.0046 17.1 7.7 0.63 10.2 0.2 4.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EGF76522.1 - 0.013 15.6 8.0 0.64 10.1 0.3 4.9 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 EGF76522.1 - 0.29 10.4 12.5 0.24 10.7 1.1 3.9 4 0 0 4 4 4 0 V-ATPase subunit H SH3_9 PF14604.6 EGF76523.1 - 8.6e-28 95.9 2.4 8.2e-13 48.0 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGF76523.1 - 1.2e-24 85.6 0.5 1e-11 44.3 0.1 2.6 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 EGF76523.1 - 3.9e-21 75.1 0.0 1.3e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EGF76523.1 - 4.5e-20 71.1 0.1 1.1e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain AAA_23 PF13476.6 EGF76523.1 - 0.25 11.8 11.6 0.44 11.0 11.6 1.4 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EGF76523.1 - 0.41 10.2 12.2 0.57 9.7 12.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 EGF76523.1 - 0.55 7.7 32.4 0.75 7.2 32.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TFIIA PF03153.13 EGF76523.1 - 4 7.3 32.0 6.9 6.5 32.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S26 PF14943.6 EGF76523.1 - 7.2 6.5 29.7 15 5.5 29.7 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 THF_DHG_CYH PF00763.23 EGF76524.1 - 6.3e-28 97.4 0.0 1.1e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGF76524.1 - 2.5e-12 46.4 0.0 3.6e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 EGF76524.1 - 0.022 14.9 0.1 0.093 12.8 0.0 2.0 2 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Brix PF04427.18 EGF76525.1 - 1.1e-38 133.3 0.0 1.5e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ribosomal_L7Ae PF01248.26 EGF76526.1 - 6.3e-26 89.9 1.8 8e-26 89.6 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RCC1 PF00415.18 EGF76527.1 - 3e-15 56.6 2.0 3.2e-06 27.7 0.1 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF76527.1 - 4.8e-15 54.9 12.4 4e-09 36.0 0.7 4.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat dUTPase PF00692.19 EGF76528.1 - 9.3e-46 154.7 0.0 1.1e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 dUTPase CoaE PF01121.20 EGF76529.1 - 2.4e-57 193.5 0.0 2.8e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGF76529.1 - 0.009 16.6 2.9 0.21 12.2 2.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGF76529.1 - 0.013 15.7 0.4 0.53 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain MICSWaP PF17018.5 EGF76530.1 - 0.093 12.3 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Spore wall protein Fzo_mitofusin PF04799.13 EGF76530.1 - 0.45 10.1 4.6 0.18 11.4 1.1 1.8 1 1 1 2 2 2 0 fzo-like conserved region Ribosomal_S18 PF01084.20 EGF76530.1 - 0.48 10.7 0.1 0.48 10.7 0.1 2.6 3 0 0 3 3 3 0 Ribosomal protein S18 XhlA PF10779.9 EGF76530.1 - 1.2 9.4 4.3 4.3 7.6 0.7 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Dmrt1 PF12374.8 EGF76530.1 - 1.9 9.0 8.4 2.2 8.8 7.6 1.5 1 1 0 1 1 1 0 Double-sex mab3 related transcription factor 1 SIL1 PF16782.5 EGF76531.1 - 0.00066 19.0 3.6 0.00074 18.8 3.6 1.0 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Symplekin_C PF12295.8 EGF76531.1 - 0.017 15.2 0.2 0.035 14.2 0.0 1.6 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal AFP_2 PF18815.1 EGF76531.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 Bacterial antifreeze protein repeat DUF4246 PF14033.6 EGF76533.1 - 5.4e-29 101.6 0.1 6.9e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) AAA_34 PF13872.6 EGF76534.1 - 0.00081 18.4 0.0 0.00083 18.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Hormone_6 PF00236.18 EGF76535.1 - 0.55 10.3 4.6 0.13 12.3 0.8 1.9 2 0 0 2 2 2 0 Glycoprotein hormone Hormone_6 PF00236.18 EGF76537.1 - 0.64 10.0 4.5 0.17 11.9 0.8 1.9 2 0 0 2 2 2 0 Glycoprotein hormone ABC_tran PF00005.27 EGF76539.1 - 1.7e-27 96.6 0.0 7.2e-27 94.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGF76539.1 - 3e-12 47.0 0.6 1.4e-08 34.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF76539.1 - 0.00019 22.0 0.5 0.0012 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGF76539.1 - 0.0009 19.0 0.1 0.13 11.9 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGF76539.1 - 0.0028 17.6 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF76539.1 - 0.0037 17.0 0.1 0.0077 16.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGF76539.1 - 0.0053 16.2 0.9 0.41 10.1 0.1 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF76539.1 - 0.01 16.2 0.1 0.17 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RRM_Rrp7 PF17799.1 EGF76539.1 - 0.03 14.1 0.7 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DCX PF03607.17 EGF76539.1 - 0.033 14.3 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Doublecortin AAA_13 PF13166.6 EGF76539.1 - 0.061 12.0 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DED PF01335.21 EGF76539.1 - 0.065 13.5 1.4 0.11 12.8 0.3 2.0 2 0 0 2 2 1 0 Death effector domain DLIC PF05783.11 EGF76539.1 - 0.072 11.9 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 EGF76539.1 - 0.14 12.1 0.1 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Asp PF00026.23 EGF76541.1 - 9.9e-14 51.5 0.1 1.5e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76541.1 - 6.4e-06 26.0 0.1 1.7e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal WDCP PF15390.6 EGF76543.1 - 0.1 11.0 4.5 0.14 10.6 4.5 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Ndc1_Nup PF09531.10 EGF76543.1 - 0.57 8.8 10.7 0.63 8.7 10.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MciZ PF13072.6 EGF76543.1 - 0.9 9.4 3.9 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ SAP PF02037.27 EGF76543.1 - 1 9.2 5.0 12 5.8 0.0 3.4 3 0 0 3 3 3 0 SAP domain Hid1 PF12722.7 EGF76543.1 - 7 4.6 8.5 9.6 4.2 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOC3p PF07540.11 EGF76545.1 - 0.076 13.5 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein Sec2p PF06428.11 EGF76545.1 - 0.47 10.4 3.3 7.3 6.6 0.1 2.4 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF76545.1 - 0.65 10.2 4.7 1.5 9.0 0.3 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Dimer_Tnp_hAT PF05699.14 EGF76546.1 - 6.1e-17 61.2 0.1 6.6e-17 61.1 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RNase_H2_suC PF08615.11 EGF76548.1 - 4.1e-17 62.7 0.3 2.6e-12 47.1 0.0 2.0 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LBP_C PF17386.2 EGF76548.1 - 0.078 12.9 0.2 0.22 11.5 0.2 1.7 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain WD40 PF00400.32 EGF76549.1 - 8.8e-37 124.5 25.0 3.4e-07 30.9 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EGF76549.1 - 0.0017 17.1 0.3 0.26 9.9 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 TPR_1 PF00515.28 EGF76550.1 - 8.7e-42 139.3 7.9 1.1e-06 28.2 0.1 14.5 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76550.1 - 1.1e-34 115.8 17.3 0.00072 19.5 0.2 15.5 16 0 0 16 16 14 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76550.1 - 4.1e-27 92.1 13.8 0.0051 16.9 0.0 13.4 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGF76550.1 - 7.7e-25 85.5 13.9 0.061 13.7 0.0 15.0 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF76550.1 - 3e-23 81.9 25.5 0.0007 19.8 0.0 12.4 11 3 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGF76550.1 - 1.7e-21 75.6 13.6 9.3e-05 22.0 0.9 12.5 12 2 4 16 16 15 5 TPR repeat TPR_19 PF14559.6 EGF76550.1 - 1.5e-18 67.1 15.1 0.00039 20.9 1.7 10.1 8 1 1 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGF76550.1 - 2.4e-16 60.1 16.7 1.8e-05 25.3 2.0 8.8 8 2 2 10 10 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGF76550.1 - 4.9e-16 58.1 24.0 0.096 13.6 0.9 14.3 13 3 3 16 16 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76550.1 - 2.1e-12 46.1 6.2 0.95 9.6 0.0 9.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGF76550.1 - 9.3e-12 44.9 0.5 0.0001 22.4 0.0 6.4 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF76550.1 - 2.2e-09 37.4 25.3 0.00011 22.4 0.1 8.7 9 1 1 10 10 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGF76550.1 - 2.5e-05 24.6 22.0 6.2 7.7 0.5 11.9 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF76550.1 - 0.0011 18.8 15.5 6.6 6.7 0.0 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_22 PF18833.1 EGF76550.1 - 0.0012 18.9 0.4 0.011 15.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGF76550.1 - 0.0015 18.9 4.9 18 5.7 0.0 5.4 4 1 1 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF76550.1 - 0.0016 18.5 0.1 0.7 10.0 0.3 3.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EGF76550.1 - 0.015 15.9 3.2 30 5.6 0.1 6.1 6 0 0 6 6 4 0 Tetratricopeptide repeat PknG_TPR PF16918.5 EGF76550.1 - 0.031 13.0 1.6 0.15 10.7 0.0 2.7 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat ChAPs PF09295.10 EGF76550.1 - 0.04 12.9 8.4 0.048 12.7 0.0 3.9 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM20_plant PF06552.12 EGF76550.1 - 0.055 13.2 0.3 6.6 6.4 0.0 3.8 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.9 EGF76550.1 - 0.059 12.8 0.1 39 3.8 0.0 4.3 4 0 0 4 4 4 0 SHNi-TPR TPR_21 PF09976.9 EGF76550.1 - 0.079 12.7 6.1 1.3 8.7 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain HEPN_AbiV PF18728.1 EGF76550.1 - 0.085 13.0 2.6 0.41 10.8 0.1 2.9 3 0 0 3 3 2 0 AbiV DUF3856 PF12968.7 EGF76550.1 - 0.1 12.7 1.2 37 4.4 0.0 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) HEPN PF05168.14 EGF76550.1 - 0.13 12.4 1.3 1 9.5 0.1 3.2 3 0 0 3 3 2 0 HEPN domain DUF1963 PF09234.10 EGF76550.1 - 0.19 12.2 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1963) SNAP PF14938.6 EGF76550.1 - 2.3 7.6 10.1 0.62 9.4 2.0 4.0 5 0 0 5 5 5 0 Soluble NSF attachment protein, SNAP Aldo_ket_red PF00248.21 EGF76551.1 - 3.6e-33 115.0 0.0 2.7e-32 112.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family NdhM PF10664.9 EGF76551.1 - 0.12 12.7 0.4 0.82 10.0 0.4 2.3 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M WD40 PF00400.32 EGF76552.1 - 4.4e-11 43.1 3.2 0.11 13.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Carm_PH PF17888.1 EGF76552.1 - 0.031 14.6 0.1 1.1 9.6 0.1 3.1 2 1 1 3 3 3 0 Carmil pleckstrin homology domain SBP56 PF05694.11 EGF76552.1 - 0.057 12.2 0.6 0.18 10.6 0.2 1.9 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) SGL PF08450.12 EGF76552.1 - 0.072 12.7 0.3 12 5.3 0.1 2.4 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF2185 PF09951.9 EGF76552.1 - 0.082 12.7 0.3 0.39 10.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) Utp14 PF04615.13 EGF76553.1 - 2.5 6.6 33.3 3.8 6.0 33.3 1.2 1 0 0 1 1 1 0 Utp14 protein RRM_1 PF00076.22 EGF76554.1 - 9.9e-09 34.9 0.0 2.4e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF76554.1 - 2.9e-06 27.3 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Vezatin PF12632.7 EGF76555.1 - 1.8e-06 27.6 0.5 1.8e-06 27.6 0.5 2.4 1 1 1 2 2 2 1 Mysoin-binding motif of peroxisomes Complex1_49kDa PF00346.19 EGF76555.1 - 0.33 10.0 2.2 2.6 7.1 1.0 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit BCS1_N PF08740.11 EGF76556.1 - 1.1e-46 159.2 0.1 1.5e-46 158.7 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGF76556.1 - 7.9e-21 74.9 0.0 1.6e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGF76556.1 - 0.00088 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGF76556.1 - 0.0046 17.1 0.1 0.016 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGF76556.1 - 0.0046 17.4 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGF76556.1 - 0.011 15.3 0.0 0.091 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGF76556.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGF76556.1 - 0.029 14.1 0.0 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGF76556.1 - 0.032 14.7 0.1 0.065 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF76556.1 - 0.037 14.4 0.0 0.098 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EGF76556.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 EGF76556.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF76556.1 - 0.11 12.7 0.1 0.61 10.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EGF76556.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PXA PF02194.15 EGF76557.1 - 7.1e-47 159.7 0.6 1.4e-46 158.8 0.6 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EGF76557.1 - 3.6e-15 56.5 0.0 9.9e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PCNA_N PF00705.18 EGF76558.1 - 7.3e-53 177.6 1.5 1.3e-52 176.9 0.8 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGF76558.1 - 1.5e-52 177.1 0.2 2.5e-52 176.4 0.2 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EGF76558.1 - 1.2e-06 28.2 0.3 1.8e-06 27.6 0.3 1.3 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 EGF76558.1 - 0.00019 20.7 0.7 0.0032 16.6 0.1 2.3 2 1 0 2 2 2 1 Hus1-like protein DNA_pol3_beta PF00712.19 EGF76558.1 - 0.035 14.2 0.1 8.1 6.6 0.0 2.8 2 1 1 3 3 3 0 DNA polymerase III beta subunit, N-terminal domain Topo_Zn_Ribbon PF08272.11 EGF76560.1 - 2.6e-14 52.6 12.7 0.94 9.2 0.1 6.6 6 0 0 6 6 6 6 Topoisomerase I zinc-ribbon-like Lipase_3 PF01764.25 EGF76560.1 - 1e-10 41.7 8.6 5.4 6.9 0.0 6.7 6 0 0 6 6 6 6 Lipase (class 3) DUF1706 PF08020.11 EGF76560.1 - 1.1e-09 38.5 1.0 14 5.5 0.0 6.4 6 0 0 6 6 6 6 Protein of unknown function (DUF1706) TPR_22 PF18833.1 EGF76560.1 - 0.00022 21.3 17.9 21 5.3 0.1 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat DUF4964 PF16334.5 EGF76560.1 - 0.00025 20.5 6.5 74 3.0 0.0 6.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4964) Phage_fiber_C PF06820.12 EGF76560.1 - 0.00078 19.7 2.8 2.4e+02 2.1 0.0 6.2 6 0 0 6 6 6 0 Putative prophage tail fibre C-terminus Pox_A14 PF05767.12 EGF76560.1 - 0.29 11.3 19.0 3.7 7.8 0.1 7.3 7 0 0 7 7 7 0 Poxvirus virion envelope protein A14 B9-C2 PF07162.11 EGF76561.1 - 3.1e-36 125.1 0.1 5.9e-36 124.2 0.1 1.4 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein Homeodomain PF00046.29 EGF76562.1 - 0.0032 17.3 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain EF-hand_7 PF13499.6 EGF76563.1 - 3e-14 53.2 0.5 3.8e-07 30.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGF76563.1 - 4.4e-10 39.7 0.1 9.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EGF76563.1 - 2.2e-08 33.4 0.0 0.003 17.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGF76563.1 - 8.7e-07 28.1 0.4 0.033 13.7 0.0 3.2 4 0 0 4 4 4 2 EF hand RRM_1 PF00076.22 EGF76564.1 - 3.1e-25 87.8 0.3 1e-16 60.5 0.0 4.3 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF76564.1 - 1.7e-07 31.3 0.1 0.015 15.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif HOIP-UBA PF16678.5 EGF76564.1 - 0.11 12.4 0.7 0.94 9.5 0.2 2.3 2 0 0 2 2 2 0 HOIP UBA domain pair Ras PF00071.22 EGF76565.1 - 5.4e-37 126.9 0.2 6.7e-37 126.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF76565.1 - 2.2e-19 69.9 0.2 5.1e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF76565.1 - 6.2e-07 29.0 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EGF76565.1 - 0.0053 17.2 0.1 0.013 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EGF76565.1 - 0.033 13.6 0.0 0.071 12.5 0.0 1.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EGF76565.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 EGF76565.1 - 0.045 13.5 0.0 0.16 11.7 0.0 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EGF76565.1 - 0.052 13.6 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cir_N PF10197.9 EGF76566.1 - 0.00018 21.6 6.1 0.00018 21.6 6.1 4.6 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR ICL PF00463.21 EGF76567.1 - 3.5e-263 873.9 0.2 4e-263 873.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGF76567.1 - 3.4e-09 36.5 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase FAD_binding_3 PF01494.19 EGF76568.1 - 1.4e-22 80.5 0.0 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGF76568.1 - 5.9e-06 26.1 0.3 9.6e-05 22.1 0.1 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGF76568.1 - 0.00035 19.9 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGF76568.1 - 0.0011 19.1 0.3 0.0036 17.5 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGF76568.1 - 0.0013 17.9 1.6 0.0073 15.4 1.6 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGF76568.1 - 0.0016 17.4 0.1 1.1 8.0 0.1 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EGF76568.1 - 0.002 17.2 1.2 5 6.1 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 EGF76568.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Hpt PF01627.23 EGF76568.1 - 0.011 15.9 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 Hpt domain Thi4 PF01946.17 EGF76568.1 - 0.012 14.8 0.1 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EGF76568.1 - 0.17 11.8 0.1 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGF76568.1 - 0.19 11.1 0.5 0.35 10.2 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Septin PF00735.18 EGF76569.1 - 1.2e-72 244.5 0.0 1.4e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Septin Kinesin PF00225.23 EGF76571.1 - 1.3e-95 320.2 1.6 1.4e-95 320.0 1.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF76571.1 - 1.5e-16 60.6 0.1 7e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding RhoGAP PF00620.27 EGF76574.1 - 5.7e-30 104.2 0.2 1.2e-29 103.1 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EGF76574.1 - 2.8e-27 94.7 42.8 2.4e-11 43.7 7.4 4.5 4 0 0 4 4 4 4 LIM domain Yippee-Mis18 PF03226.14 EGF76574.1 - 9.9 6.4 16.8 5.4 7.3 6.4 3.4 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Clathrin PF00637.20 EGF76575.1 - 2.9e-08 33.7 4.1 0.012 15.4 0.1 4.5 2 2 1 3 3 3 3 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 EGF76575.1 - 3.3e-08 33.7 2.7 0.00019 21.6 0.2 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EGF76575.1 - 1.3e-06 28.0 10.5 4.9 7.5 0.2 9.7 10 1 1 11 11 10 1 Tetratricopeptide repeat WD40 PF00400.32 EGF76575.1 - 2.7e-05 24.8 0.2 0.053 14.4 0.0 4.7 3 0 0 3 3 3 1 WD domain, G-beta repeat TPR_12 PF13424.6 EGF76575.1 - 5.7e-05 23.3 9.0 3.9 7.8 0.0 7.3 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF76575.1 - 0.0001 22.9 1.9 0.18 12.5 0.1 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF76575.1 - 0.00011 22.8 0.1 87 4.3 0.0 7.4 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF76575.1 - 0.00086 19.5 0.1 30 5.3 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76575.1 - 0.0023 17.9 10.8 11 6.3 0.0 7.9 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF76575.1 - 0.0052 17.3 5.6 43 4.7 0.0 6.7 7 2 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 EGF76575.1 - 0.033 14.3 7.9 1.3 9.1 0.1 4.3 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 EGF76575.1 - 0.051 13.8 8.3 48 4.5 0.0 7.4 8 0 0 8 8 7 0 PPR repeat ANAPC3 PF12895.7 EGF76575.1 - 0.054 13.7 9.4 8.7 6.7 0.5 6.4 3 1 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGF76575.1 - 0.33 11.3 14.1 9 6.8 0.0 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF76575.1 - 0.48 11.2 5.0 36 5.3 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF76575.1 - 5.8 6.9 18.2 2.5 8.1 0.4 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Formyl_trans_N PF00551.19 EGF76576.1 - 9.8e-26 90.6 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGF76576.1 - 1.6e-11 44.3 0.0 4.7e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain Peptidase_M36 PF02128.15 EGF76577.1 - 8.8e-135 449.6 1.4 8.8e-135 449.6 1.4 1.6 2 0 0 2 2 2 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF76577.1 - 7.2e-09 35.3 1.9 1.7e-08 34.1 1.6 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EGF76577.1 - 0.041 14.4 0.3 0.089 13.4 0.3 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Mucin PF01456.17 EGF76577.1 - 0.38 10.8 29.3 1.1 9.2 29.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 EGF76577.1 - 5.6 5.0 12.9 7.6 4.5 12.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3888 PF13027.6 EGF76579.1 - 0.0079 16.6 1.0 0.04 14.3 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3888) zf-RING_7 PF02591.15 EGF76579.1 - 0.15 12.2 0.0 0.98 9.7 0.0 2.1 2 0 0 2 2 2 0 C4-type zinc ribbon domain Peptidase_C97 PF05903.14 EGF76580.1 - 0.00052 19.9 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain SieB PF14163.6 EGF76581.1 - 0.17 11.4 12.2 0.1 12.1 8.8 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B MHB PF16525.5 EGF76581.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.5 4 0 0 4 4 4 0 Haemophore, haem-binding PX PF00787.24 EGF76582.1 - 1.9e-23 82.6 0.2 2.3e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 PX domain Ras PF00071.22 EGF76583.1 - 3.6e-53 179.5 0.0 4.2e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF76583.1 - 7.9e-21 74.5 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF76583.1 - 4.5e-07 29.5 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Utp21 PF04192.12 EGF76584.1 - 1.3e-52 178.6 0.1 2.2e-52 177.9 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EGF76584.1 - 2.4e-17 63.0 0.2 6.7e-06 26.3 0.0 6.3 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF76584.1 - 1.9e-15 57.0 27.2 1e-06 29.3 1.2 9.3 12 0 0 12 12 12 4 WD domain, G-beta repeat Nup160 PF11715.8 EGF76584.1 - 2.1e-05 23.4 7.9 0.047 12.3 0.0 4.7 3 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF76584.1 - 0.0011 18.0 1.6 0.076 12.0 0.1 3.5 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGF76584.1 - 0.0029 16.4 0.7 2 7.0 0.1 3.3 2 1 2 4 4 4 2 Nup133 N terminal like WD40_like PF17005.5 EGF76584.1 - 0.043 13.1 1.9 0.99 8.7 0.1 3.1 2 2 0 2 2 2 0 WD40-like domain DUF1513 PF07433.11 EGF76584.1 - 0.067 12.3 0.0 48 2.9 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1513) RAB3GAP2_N PF14655.6 EGF76584.1 - 0.095 11.9 1.1 13 4.9 0.0 3.7 4 1 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Clat_adaptor_s PF01217.20 EGF76585.1 - 9e-44 148.9 3.8 1.1e-43 148.6 3.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1460 PF07313.12 EGF76585.1 - 0.069 12.5 0.1 0.074 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) ERCC4 PF02732.15 EGF76586.1 - 5.5e-20 72.1 0.0 1.4e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EGF76586.1 - 0.0082 16.5 1.0 0.18 12.2 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain Ribosomal_L16 PF00252.18 EGF76587.1 - 2.9e-39 134.1 0.5 3.2e-39 134.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Glyco_hydro_36 PF17167.4 EGF76587.1 - 0.13 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF4471 PF14740.6 EGF76589.1 - 6.7e-86 288.3 9.2 4.5e-84 282.3 9.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 EGF76589.1 - 5.3e-27 93.9 0.1 1.1e-26 92.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) CbbQ_C PF08406.10 EGF76589.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal Mt_ATP-synt_B PF05405.14 EGF76591.1 - 5.1e-40 136.8 1.3 6.4e-40 136.4 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Alg14 PF08660.11 EGF76592.1 - 2.4e-60 203.4 0.1 2.7e-60 203.3 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Cnd3 PF12719.7 EGF76593.1 - 1.2e-49 169.1 5.6 1.2e-49 169.1 5.6 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 EGF76593.1 - 1.1e-05 25.6 8.4 0.11 12.6 0.1 4.9 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EGF76593.1 - 0.0008 19.4 0.0 3.5 7.8 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGF76593.1 - 0.0011 19.4 3.0 0.025 15.0 0.2 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EGF76593.1 - 0.0019 18.3 8.4 1.2 9.6 0.1 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGF76593.1 - 0.019 15.5 2.8 3.9 8.1 0.2 4.1 2 1 2 4 4 4 0 HEAT-like repeat TPR_5 PF12688.7 EGF76593.1 - 0.069 13.4 3.6 2.4 8.4 0.3 3.0 3 0 0 3 3 3 0 Tetratrico peptide repeat Dpy-30 PF05186.13 EGF76594.1 - 3.7e-16 58.5 0.0 4.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif LSM PF01423.22 EGF76595.1 - 9.2e-16 57.3 0.0 1.1e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.13 EGF76595.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin RINGv PF12906.7 EGF76596.1 - 6.7e-10 38.9 9.0 1.6e-09 37.7 9.0 1.7 1 0 0 1 1 1 1 RING-variant domain TctB PF07331.11 EGF76596.1 - 3.2 8.0 8.0 17 5.6 8.0 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family WD40 PF00400.32 EGF76597.1 - 1.2e-30 105.1 19.3 4.2e-05 24.2 0.0 10.7 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76597.1 - 1e-07 32.1 0.1 0.0002 21.6 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EGF76597.1 - 0.0009 19.7 0.8 0.0034 17.8 0.8 2.1 1 0 0 1 1 1 1 EF-hand domain pair Nup160 PF11715.8 EGF76597.1 - 0.0015 17.3 3.9 0.55 8.8 0.0 4.4 4 1 1 5 5 5 1 Nucleoporin Nup120/160 EF-hand_1 PF00036.32 EGF76597.1 - 0.014 14.9 0.1 0.042 13.4 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGF76597.1 - 0.037 14.0 0.5 0.24 11.4 0.2 2.7 2 1 0 2 2 2 0 EF-hand domain LigD_N PF13298.6 EGF76597.1 - 0.059 13.7 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) EF-hand_8 PF13833.6 EGF76597.1 - 0.092 12.6 3.2 0.08 12.8 0.6 2.4 2 0 0 2 2 2 0 EF-hand domain pair NinE PF05322.11 EGF76598.1 - 0.13 12.2 0.3 0.4 10.6 0.3 1.7 1 0 0 1 1 1 0 NINE Protein Ripply PF14998.6 EGF76598.1 - 0.51 11.0 3.3 3.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Transcription Regulator Cullin PF00888.22 EGF76599.1 - 5.8e-24 84.7 1.4 9e-24 84.0 0.1 1.8 2 0 0 2 2 2 1 Cullin family TERT_thumb PF17984.1 EGF76599.1 - 0.059 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Telomerase reverse transcriptase thumb DNA binding domain Moulting_cycle PF04870.16 EGF76599.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Moulting cycle Mito_carr PF00153.27 EGF76601.1 - 7.2e-63 208.5 0.5 4.9e-24 84.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PEP-CTERM PF07589.11 EGF76601.1 - 0.2 11.8 0.8 0.65 10.2 0.8 1.9 1 0 0 1 1 1 0 PEP-CTERM motif AAA_22 PF13401.6 EGF76602.1 - 0.041 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGF76602.1 - 0.091 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 EGF76602.1 - 0.12 12.8 0.0 1.3 9.4 0.0 2.7 2 1 0 2 2 2 0 RNA helicase Death_2 PF14786.6 EGF76603.1 - 0.87 9.5 3.2 0.5 10.3 0.1 2.1 2 1 0 2 2 2 0 Tube Death domain AAA_29 PF13555.6 EGF76604.1 - 0.19 11.5 0.2 25 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain IFT57 PF10498.9 EGF76605.1 - 0.061 12.3 0.9 0.078 11.9 0.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tup_N PF08581.10 EGF76605.1 - 0.39 11.1 3.1 0.48 10.8 1.1 2.0 1 1 1 2 2 2 0 Tup N-terminal Med21 PF11221.8 EGF76605.1 - 2.7 8.3 5.3 6.1 7.1 5.3 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex NMT1 PF09084.11 EGF76606.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like RHSP PF07999.11 EGF76607.1 - 0.0035 16.2 0.1 0.49 9.2 0.0 2.3 2 1 0 2 2 2 2 Retrotransposon hot spot protein MeaB PF03308.16 EGF76607.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGF76607.1 - 0.024 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EGF76607.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EGF76607.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC SF3b10 PF07189.11 EGF76608.1 - 7.3e-35 118.9 0.0 8e-35 118.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) S4 PF01479.25 EGF76609.1 - 4.1e-13 48.8 0.8 4.1e-13 48.8 0.8 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EGF76609.1 - 0.00033 21.5 0.2 0.0011 19.8 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain FAD_binding_1 PF00667.20 EGF76610.1 - 1e-38 133.1 0.0 1.6e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGF76610.1 - 2.3e-32 112.2 0.0 5.2e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGF76610.1 - 6.5e-10 39.6 0.0 1.4e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGF76610.1 - 0.003 17.8 0.0 2 8.7 0.0 2.6 1 1 1 2 2 2 2 Flavodoxin domain DUF563 PF04577.14 EGF76611.1 - 1.3e-20 74.4 0.0 2.3e-20 73.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) COMP PF11598.8 EGF76611.1 - 0.053 14.0 0.2 0.14 12.6 0.2 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein His_Phos_1 PF00300.22 EGF76612.1 - 2.7e-42 144.7 0.0 3.5e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ALG11_N PF15924.5 EGF76613.1 - 1.8e-81 273.2 1.2 2.4e-81 272.7 1.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGF76613.1 - 1.3e-26 93.1 0.0 2.3e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF76613.1 - 6.3e-12 46.1 0.0 1.5e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 OSCP PF00213.18 EGF76614.1 - 4e-43 147.5 1.8 4.7e-43 147.3 1.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit BTB PF00651.31 EGF76615.1 - 3.7e-07 30.4 0.0 8.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain APG6_N PF17675.1 EGF76616.1 - 0.011 16.3 21.5 0.011 16.3 21.5 5.0 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF1192 PF06698.11 EGF76616.1 - 0.9 9.6 0.0 0.9 9.6 0.0 5.9 4 1 2 6 6 6 0 Protein of unknown function (DUF1192) Golgin_A5 PF09787.9 EGF76616.1 - 1.3 8.4 70.2 3.1 7.2 9.7 5.0 1 1 5 6 6 6 0 Golgin subfamily A member 5 DUF2333 PF10095.9 EGF76616.1 - 4.9 6.1 11.9 0.13 11.2 0.8 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) PHD PF00628.29 EGF76617.1 - 2e-06 27.6 5.0 3.7e-06 26.7 5.0 1.4 1 0 0 1 1 1 1 PHD-finger Bromo_TP PF07524.13 EGF76617.1 - 0.081 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Bromodomain associated zf-RING_2 PF13639.6 EGF76617.1 - 0.47 10.8 5.7 0.88 10.0 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 EGF76617.1 - 0.65 9.8 6.1 1.4 8.7 6.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger Asp PF00026.23 EGF76618.1 - 5.5e-54 183.7 2.4 7e-54 183.4 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF76618.1 - 1.4e-07 31.9 4.2 4.5e-06 27.0 1.9 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGF76618.1 - 0.0075 16.9 0.1 2.3 8.9 0.0 3.1 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 EGF76618.1 - 0.0082 15.9 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF76618.1 - 0.075 13.6 0.0 13 6.4 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Aldedh PF00171.22 EGF76619.1 - 2.4e-95 319.8 0.0 3e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_A_bac PF01000.26 EGF76620.1 - 2.3e-27 95.6 0.0 3.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGF76620.1 - 4e-21 74.2 0.0 5.9e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Med12 PF09497.10 EGF76621.1 - 2.5e-15 56.5 0.0 1e-14 54.6 0.0 2.2 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 PCI PF01399.27 EGF76622.1 - 1.2e-20 73.9 1.4 1.5e-19 70.4 0.0 2.9 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EGF76622.1 - 9.8e-18 64.0 4.0 3.2e-17 62.3 4.0 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain TPR_19 PF14559.6 EGF76622.1 - 0.0041 17.6 1.6 2.3 8.8 0.1 3.6 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF1922 PF09082.10 EGF76622.1 - 0.13 12.5 0.3 0.46 10.8 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Claudin_3 PF06653.11 EGF76623.1 - 1.2 9.0 17.9 0.17 11.8 3.6 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Pkinase PF00069.25 EGF76624.1 - 2.4e-68 230.3 0.4 3.1e-68 230.0 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76624.1 - 1.2e-36 126.3 0.4 1.6e-36 126.0 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF76624.1 - 5.2e-08 32.1 0.1 8.8e-08 31.3 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF76624.1 - 1.2e-06 28.1 0.1 2.4e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF76624.1 - 0.0005 19.5 0.2 0.0014 18.1 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF76624.1 - 0.0012 18.5 0.3 0.0021 17.7 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGF76624.1 - 0.13 12.2 0.1 0.41 10.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lipase_GDSL_2 PF13472.6 EGF76625.1 - 8.8e-19 68.6 0.1 2e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGF76625.1 - 1.5e-14 54.5 0.0 1.8e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sel1 PF08238.12 EGF76626.1 - 2.3e-15 56.7 15.9 1.4e-05 25.6 0.1 6.4 7 0 0 7 7 7 3 Sel1 repeat PhoU PF01895.19 EGF76626.1 - 0.0091 16.4 0.9 0.021 15.3 0.9 1.6 1 0 0 1 1 1 1 PhoU domain Rootletin PF15035.6 EGF76626.1 - 0.061 13.4 2.4 0.1 12.6 2.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TolA_bind_tri PF16331.5 EGF76626.1 - 0.12 12.5 0.8 0.27 11.3 0.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 EGF76626.1 - 0.19 12.2 2.2 0.36 11.3 2.2 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DUF2330 PF10092.9 EGF76627.1 - 0.17 10.9 0.1 1.6 7.7 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) DUF2357 PF09823.9 EGF76630.1 - 0.053 12.8 0.3 0.066 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) ING PF12998.7 EGF76630.1 - 1.1 9.9 5.6 1.3 9.6 0.4 2.4 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PAG PF15347.6 EGF76632.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Asp PF00026.23 EGF76633.1 - 9.2e-14 51.6 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76633.1 - 0.0015 18.3 0.1 0.013 15.2 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Diacid_rec PF05651.13 EGF76633.1 - 0.13 12.0 0.1 0.33 10.6 0.1 1.6 2 0 0 2 2 2 0 Putative sugar diacid recognition HNH_2 PF13391.6 EGF76634.1 - 6.3e-06 26.2 0.1 0.00032 20.8 0.0 2.8 2 0 0 2 2 2 2 HNH endonuclease Arm-DNA-bind_4 PF14657.6 EGF76635.1 - 0.036 13.8 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain DUF1283 PF06932.11 EGF76635.1 - 0.085 13.1 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Asp PF00026.23 EGF76636.1 - 9.6e-07 28.5 0.2 1.3e-06 28.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease U3_assoc_6 PF08640.11 EGF76637.1 - 0.083 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 YlbD_coat PF14071.6 EGF76638.1 - 1 9.7 10.4 0.093 13.0 4.6 2.1 1 1 1 2 2 2 0 Putative coat protein PTCRA PF15028.6 EGF76639.1 - 0.025 14.3 0.8 0.037 13.7 0.8 1.3 1 0 0 1 1 1 0 Pre-T-cell antigen receptor SPT2 PF08243.11 EGF76640.1 - 1.3e-22 80.4 3.6 1.3e-22 80.4 3.6 1.4 2 0 0 2 2 2 1 SPT2 chromatin protein Imm-NTF2 PF15655.6 EGF76640.1 - 0.066 13.5 0.2 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 NTF2 fold immunity protein Sld5 PF05916.11 EGF76641.1 - 0.00024 21.5 0.0 0.00036 20.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 EGF76641.1 - 0.034 14.4 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus zf-RING_4 PF14570.6 EGF76642.1 - 4.1e-22 77.7 12.4 8.2e-22 76.7 12.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGF76642.1 - 1.8e-07 30.9 7.2 4.2e-07 29.7 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EGF76642.1 - 3.6e-07 29.9 0.0 2.1e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 EGF76642.1 - 8.9e-06 25.5 8.1 0.002 17.9 6.1 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGF76642.1 - 8.4e-05 22.8 10.5 8.4e-05 22.8 10.5 1.9 2 0 0 2 2 2 1 Ring finger domain Nup35_RRM PF05172.13 EGF76642.1 - 0.00028 20.8 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGF76642.1 - 0.00032 20.6 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 EGF76642.1 - 0.0012 18.8 5.6 0.0025 17.8 5.6 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EGF76642.1 - 0.0027 17.8 3.1 0.0069 16.5 3.1 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Rtf2 PF04641.12 EGF76642.1 - 0.012 14.9 1.6 0.018 14.5 1.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 EGF76642.1 - 0.055 13.4 11.6 0.12 12.2 11.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF76642.1 - 3.9 7.6 12.6 0.6 10.2 5.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger FYVE_2 PF02318.16 EGF76642.1 - 5.3 7.3 7.4 2.4 8.4 3.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 EGF76642.1 - 9.3 6.2 17.6 0.23 11.3 10.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pro_isomerase PF00160.21 EGF76644.1 - 1.8e-49 168.0 0.0 2.9e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EGF76644.1 - 0.025 14.7 1.7 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76644.1 - 0.49 10.7 1.7 4.1 7.8 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF76644.1 - 0.63 10.8 2.6 11 6.9 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_64 PF09258.10 EGF76645.1 - 3.1e-60 203.5 0.3 3.6e-60 203.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 EGF76645.1 - 0.031 14.2 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Tudor_2 PF18104.1 EGF76646.1 - 4.7e-06 26.2 0.1 9.1e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Robl_LC7 PF03259.17 EGF76647.1 - 1.3e-15 56.9 0.0 1.6e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DNA_gyraseA_C PF03989.13 EGF76647.1 - 0.049 13.1 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Rtf2 PF04641.12 EGF76650.1 - 1.6e-71 240.7 5.8 2e-71 240.4 5.8 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF2685 PF10886.8 EGF76650.1 - 0.058 13.6 0.2 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) NinG PF05766.12 EGF76650.1 - 0.094 12.6 4.9 0.18 11.7 4.9 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein zf-Nse PF11789.8 EGF76650.1 - 0.16 11.8 1.7 12 5.9 0.0 2.9 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit TRAPPC9-Trs120 PF08626.11 EGF76651.1 - 6.3e-159 530.7 0.0 6.6e-101 338.5 0.0 3.1 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_hydro_18 PF00704.28 EGF76651.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 CNOT11 PF10155.9 EGF76652.1 - 4.6e-40 136.7 3.6 8.8e-40 135.7 3.6 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 DnaA_N PF11638.8 EGF76652.1 - 0.017 14.9 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 DnaA N-terminal domain MFS_1 PF07690.16 EGF76654.1 - 1.5e-27 96.5 14.8 1.5e-27 96.5 14.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ANAPC4_WD40 PF12894.7 EGF76654.1 - 7.7e-08 32.5 0.0 0.84 10.0 0.0 4.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF76654.1 - 1e-05 26.2 2.9 0.026 15.4 0.1 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat eIF2A PF08662.11 EGF76654.1 - 0.00027 20.9 0.0 0.07 13.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MFS_1_like PF12832.7 EGF76654.1 - 0.00037 19.5 8.9 0.037 12.9 0.5 2.9 1 1 1 2 2 2 2 MFS_1 like family ATG22 PF11700.8 EGF76654.1 - 0.029 13.0 10.4 0.0084 14.8 1.8 2.4 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like MFS_3 PF05977.13 EGF76654.1 - 0.079 11.3 11.0 0.26 9.6 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 EGF76654.1 - 0.11 11.3 20.9 4 6.2 20.9 2.3 1 1 0 1 1 1 0 Sugar (and other) transporter Peptidase_M36 PF02128.15 EGF76655.1 - 8.6e-162 538.5 3.7 1.1e-161 538.2 3.7 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF76655.1 - 7.4e-06 25.7 1.9 8.9e-06 25.4 0.8 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGF76655.1 - 0.012 15.5 0.2 0.041 13.8 0.0 1.9 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain DUF3339 PF11820.8 EGF76655.1 - 0.19 11.9 0.2 0.37 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3339) Ecm29 PF13001.7 EGF76657.1 - 2.8e-135 451.8 2.2 8.8e-132 440.3 0.5 3.4 3 0 0 3 3 3 2 Proteasome stabiliser HEAT_2 PF13646.6 EGF76657.1 - 1.9e-12 47.4 2.3 0.77 10.2 0.0 10.9 10 1 2 12 12 12 2 HEAT repeats HEAT PF02985.22 EGF76657.1 - 5.7e-12 44.8 4.6 0.91 10.0 0.0 10.9 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.6 EGF76657.1 - 3.4e-10 40.2 1.1 2.4 8.7 0.0 8.1 7 0 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGF76657.1 - 6.4e-07 29.9 0.1 0.052 14.1 0.0 5.1 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EGF76657.1 - 1.2e-05 24.6 2.5 0.56 9.3 0.1 5.2 6 0 0 6 6 6 2 Interferon-related developmental regulator (IFRD) F-box-like PF12937.7 EGF76657.1 - 6.1e-05 22.8 0.0 0.0002 21.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like Cnd1 PF12717.7 EGF76657.1 - 0.19 11.8 4.8 3.9 7.5 0.0 4.9 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 FlgT_M PF16539.5 EGF76658.1 - 0.12 12.5 1.1 2.9 8.0 0.3 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain FRG1 PF06229.12 EGF76659.1 - 5.9e-20 71.8 2.1 5.9e-20 71.8 2.1 2.4 2 1 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 EGF76659.1 - 1.8e-06 28.2 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Fascin domain PTPS PF01242.19 EGF76660.1 - 2.3e-33 114.8 0.1 2.6e-33 114.6 0.1 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase V-ATPase_H_N PF03224.14 EGF76661.1 - 2.6e-55 187.9 7.0 2.6e-55 187.9 7.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGF76661.1 - 6.3e-44 148.8 3.8 2.5e-42 143.7 0.1 3.2 3 1 1 4 4 4 1 V-ATPase subunit H Arm_2 PF04826.13 EGF76661.1 - 0.0064 16.0 0.1 0.0064 16.0 0.1 2.1 2 1 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 EGF76661.1 - 0.017 15.5 0.1 0.26 11.7 0.0 2.7 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.22 EGF76661.1 - 0.11 12.8 0.0 0.65 10.4 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat HMG-CoA_red PF00368.18 EGF76662.1 - 4.3e-94 315.5 0.1 6.2e-94 315.0 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Arf PF00025.21 EGF76663.1 - 1.3e-50 171.2 0.0 1.5e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF76663.1 - 5.1e-12 46.1 0.0 7.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGF76663.1 - 7.5e-12 45.1 1.8 9.3e-08 31.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGF76663.1 - 7.4e-11 41.9 0.0 8.6e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGF76663.1 - 1.3e-07 31.6 0.0 2.5e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGF76663.1 - 1.3e-06 27.9 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGF76663.1 - 7.3e-05 22.2 0.0 9.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGF76663.1 - 0.00012 21.7 0.0 0.00037 20.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 EGF76663.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 EGF76663.1 - 0.036 13.6 1.3 0.49 9.9 0.5 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF76663.1 - 0.11 12.5 0.2 6 6.9 0.0 2.2 1 1 1 2 2 2 0 Dynamin family DUF2025 PF09634.10 EGF76663.1 - 0.11 12.5 0.1 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) DUF4804 PF16062.5 EGF76663.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) SAM_PNT PF02198.16 EGF76663.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Condensation PF00668.20 EGF76664.1 - 1.9e-29 102.7 0.0 2.6e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 EGF76665.1 - 2.4e-43 148.3 0.1 2.8e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme zf-LITAF-like PF10601.9 EGF76666.1 - 4.9e-17 61.9 12.1 6.8e-17 61.5 12.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Kelch_4 PF13418.6 EGF76667.1 - 0.00036 20.5 0.2 0.33 11.0 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGF76667.1 - 0.001 19.0 2.2 0.44 10.6 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGF76667.1 - 0.15 12.0 1.0 0.6 10.2 0.3 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 EGF76668.1 - 8.2e-18 64.2 11.5 4.8e-10 39.3 0.1 5.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF76668.1 - 6.7e-15 54.8 13.4 0.0037 17.5 0.3 6.0 3 1 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EGF76668.1 - 9.9e-15 54.1 7.7 0.0005 20.0 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGF76668.1 - 6.8e-11 41.6 6.3 0.00037 20.0 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EGF76668.1 - 5.8e-10 39.2 12.1 0.0036 17.5 0.1 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGF76668.1 - 4.7e-05 23.2 12.3 1.8 8.7 0.3 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 EGF76669.1 - 1.2e-22 79.6 9.5 2.3e-11 43.5 0.1 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF76669.1 - 9.8e-16 57.4 6.2 6.4e-05 23.1 0.1 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EGF76669.1 - 1.1e-14 54.2 4.6 7.9e-05 22.8 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGF76669.1 - 6.9e-12 45.1 2.6 0.00038 20.4 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGF76669.1 - 2.5e-11 43.0 0.6 0.0036 16.8 0.1 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EGF76669.1 - 5.7e-09 35.6 5.8 0.0011 18.8 0.2 4.6 4 0 0 4 4 4 3 Kelch motif Tubulin PF00091.25 EGF76672.1 - 4.4e-49 167.4 0.0 7.4e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF76672.1 - 2.4e-20 73.0 0.0 6.3e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 EGF76672.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Sulfate_transp PF00916.20 EGF76674.1 - 4.8e-46 157.2 27.9 7.3e-46 156.6 27.9 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EGF76674.1 - 3.5e-17 62.3 0.0 6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EGF76674.1 - 1.2e-07 31.3 0.1 2.7e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 STAS domain Asp PF00026.23 EGF76675.1 - 5.2e-08 32.7 0.9 2.5e-07 30.4 0.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76675.1 - 4.5e-05 23.3 0.0 0.00029 20.7 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF76675.1 - 0.026 15.2 0.3 0.32 11.7 0.2 2.4 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 EGF76675.1 - 0.031 14.8 0.0 0.24 12.0 0.2 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Dynactin_p22 PF07426.11 EGF76676.1 - 0.026 14.4 0.5 0.052 13.4 0.5 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 DivIC PF04977.15 EGF76678.1 - 4.6e-05 23.1 2.0 7.7e-05 22.4 2.0 1.4 1 0 0 1 1 1 1 Septum formation initiator Cast PF10174.9 EGF76678.1 - 0.00011 20.7 1.2 0.00013 20.3 1.2 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Macoilin PF09726.9 EGF76678.1 - 0.00017 20.3 1.1 0.00022 20.0 1.1 1.1 1 0 0 1 1 1 1 Macoilin family DUF2383 PF09537.10 EGF76678.1 - 0.0019 18.5 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) MAD PF05557.13 EGF76678.1 - 0.0029 16.1 0.4 0.0032 15.9 0.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF812 PF05667.11 EGF76678.1 - 0.0044 16.0 0.8 0.0053 15.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) V-SNARE PF05008.15 EGF76678.1 - 0.0067 16.8 3.0 0.014 15.7 3.0 1.5 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus YabA PF06156.13 EGF76678.1 - 0.0092 16.6 0.6 0.17 12.5 0.0 2.2 1 1 1 2 2 2 1 Initiation control protein YabA MIF4G_like_2 PF09090.11 EGF76678.1 - 0.011 15.3 0.6 0.017 14.6 0.6 1.3 1 0 0 1 1 1 0 MIF4G like DUF1664 PF07889.12 EGF76678.1 - 0.014 15.5 0.9 0.022 14.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Vps54 PF07928.12 EGF76678.1 - 0.018 15.5 0.5 0.048 14.1 0.5 1.8 1 0 0 1 1 1 0 Vps54-like protein ATG16 PF08614.11 EGF76678.1 - 0.021 15.1 1.6 0.021 15.1 1.6 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EGF76678.1 - 0.021 14.9 0.1 0.038 14.1 0.1 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF4201 PF13870.6 EGF76678.1 - 0.026 14.3 8.5 0.073 12.8 8.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 EGF76678.1 - 0.026 13.4 2.4 0.036 12.9 2.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HAP1_N PF04849.13 EGF76678.1 - 0.026 13.7 3.5 0.034 13.3 3.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region NAM-associated PF14303.6 EGF76678.1 - 0.031 15.0 1.2 0.047 14.4 1.2 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain KxDL PF10241.9 EGF76678.1 - 0.038 14.3 2.5 0.14 12.5 2.3 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein BST2 PF16716.5 EGF76678.1 - 0.048 14.2 1.4 0.048 14.2 1.4 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FliJ PF02050.16 EGF76678.1 - 0.048 13.9 0.6 0.076 13.2 0.6 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein CortBP2 PF09727.9 EGF76678.1 - 0.049 13.5 4.0 0.15 11.9 3.7 1.7 1 1 1 2 2 2 0 Cortactin-binding protein-2 DUF3349 PF11829.8 EGF76678.1 - 0.059 14.2 0.1 0.11 13.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) TMPIT PF07851.13 EGF76678.1 - 0.059 12.6 1.7 0.08 12.2 1.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CRPV_capsid PF08762.10 EGF76678.1 - 0.07 12.8 1.1 0.11 12.2 1.1 1.3 1 0 0 1 1 1 0 CRPV capsid protein like SlyX PF04102.12 EGF76678.1 - 0.07 13.8 0.9 0.31 11.7 0.3 2.1 1 1 1 2 2 2 0 SlyX APG6_N PF17675.1 EGF76678.1 - 0.084 13.4 2.0 0.12 12.9 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 EGF76678.1 - 0.099 12.9 0.4 0.17 12.2 0.4 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain FAM76 PF16046.5 EGF76678.1 - 0.12 11.7 3.1 0.16 11.3 3.1 1.1 1 0 0 1 1 1 0 FAM76 protein ParE_toxin PF05016.15 EGF76678.1 - 0.12 13.0 0.3 0.19 12.4 0.1 1.5 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Fib_alpha PF08702.10 EGF76678.1 - 0.18 12.0 4.4 0.27 11.4 3.8 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 EGF76678.1 - 0.21 11.8 4.7 0.29 11.3 4.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Sporozoite_P67 PF05642.11 EGF76678.1 - 1.3 7.1 10.7 1.8 6.6 10.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 EGF76678.1 - 1.7 6.7 14.2 2.1 6.5 14.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CHCH PF06747.13 EGF76681.1 - 4.9e-08 32.9 2.7 1.2e-07 31.6 2.7 1.7 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EGF76681.1 - 0.1 13.1 1.0 0.16 12.4 1.0 1.4 1 0 0 1 1 1 0 GCK domain MIF4G PF02854.19 EGF76682.1 - 1.6e-50 171.7 2.7 4e-21 75.6 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EGF76682.1 - 1.5e-34 119.7 5.8 1.5e-34 119.7 5.8 2.0 2 0 0 2 2 2 1 Up-frameshift suppressor 2 TRAP_alpha PF03896.16 EGF76682.1 - 0.0078 15.5 9.5 0.077 12.2 0.1 2.4 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit Mito_carr PF00153.27 EGF76683.1 - 3e-30 104.0 6.0 3.2e-14 52.6 0.5 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PAC4 PF16093.5 EGF76684.1 - 1.1e-16 60.8 0.2 1.1e-16 60.8 0.2 1.6 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 HMG_box PF00505.19 EGF76685.1 - 1.1e-13 51.4 0.4 2.4e-13 50.3 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF76685.1 - 0.0027 18.3 0.8 0.0075 16.8 0.8 1.7 1 0 0 1 1 1 1 HMG-box domain RRM_1 PF00076.22 EGF76686.1 - 2.4e-16 59.3 0.0 3.9e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF76686.1 - 1e-06 28.3 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5603 PF18231.1 EGF76686.1 - 0.076 13.3 0.0 0.099 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5603) RRM_occluded PF16842.5 EGF76686.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Peptidase_S41 PF03572.18 EGF76687.1 - 7.6e-14 51.6 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 ATG2_CAD PF13329.6 EGF76687.1 - 0.095 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif PDZ_4 PF17816.1 EGF76687.1 - 0.099 13.1 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 PDZ domain DNA_pol3_beta_2 PF02767.16 EGF76687.1 - 0.1 12.8 1.2 0.39 10.9 0.1 2.3 3 0 0 3 3 3 0 DNA polymerase III beta subunit, central domain RPN7 PF10602.9 EGF76688.1 - 1.6e-49 168.0 0.0 3e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGF76688.1 - 1.8e-16 60.5 0.3 5.6e-16 59.0 0.3 1.9 1 0 0 1 1 1 1 PCI domain Vps16_N PF04841.13 EGF76689.1 - 9.9e-100 334.1 0.0 1.4e-99 333.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EGF76689.1 - 7e-64 215.9 1.4 1.2e-63 215.2 1.4 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EGF76689.1 - 0.088 13.1 0.1 5.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cpn10 PF00166.21 EGF76690.1 - 1.5e-25 89.0 0.0 1.7e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit WD40 PF00400.32 EGF76691.1 - 2.6e-26 91.4 15.6 4.8e-05 24.0 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 EGF76691.1 - 1.2e-12 47.3 13.5 0.0003 19.6 0.0 6.0 2 1 5 7 7 7 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGF76691.1 - 2.6e-05 24.4 2.7 0.75 10.1 0.0 4.7 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGF76691.1 - 6.5e-05 22.6 0.5 0.00022 20.9 0.4 2.1 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 EGF76691.1 - 0.00024 21.5 0.0 27 5.4 0.0 4.5 3 1 1 4 4 4 0 PQQ-like domain WD40_like PF17005.5 EGF76691.1 - 0.0075 15.6 0.5 0.13 11.6 0.2 2.2 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EGF76691.1 - 0.0089 15.0 1.3 0.47 9.4 0.1 2.8 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HisG PF01634.18 EGF76692.1 - 4.8e-52 176.1 0.1 6.9e-52 175.6 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGF76692.1 - 3.6e-25 87.9 0.0 9.1e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EGF76692.1 - 0.00016 21.7 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Zn_clus PF00172.18 EGF76693.1 - 5.7e-06 26.4 8.8 1e-05 25.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EGF76694.1 - 6.6e-18 64.8 8.9 4.8e-06 27.2 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76694.1 - 9.7e-08 32.2 0.2 0.19 12.0 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGF76694.1 - 0.017 15.2 0.2 3.2 7.9 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PCI PF01399.27 EGF76695.1 - 1.2e-10 41.8 0.0 2.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain NBD_C PF17042.5 EGF76695.1 - 0.013 16.0 0.3 0.029 14.9 0.3 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain HA2 PF04408.23 EGF76696.1 - 4.9e-21 75.1 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGF76696.1 - 9.3e-19 67.8 0.4 7.9e-17 61.6 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGF76696.1 - 2.4e-12 47.0 0.0 6.1e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGF76696.1 - 1.4e-07 31.5 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF76696.1 - 2.2e-05 24.8 0.2 7.6e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGF76696.1 - 0.044 14.3 0.0 0.55 10.8 0.0 2.6 3 0 0 3 3 3 0 ABC transporter ATPase PF06745.13 EGF76696.1 - 0.086 12.2 0.3 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_34 PF13872.6 EGF76696.1 - 0.093 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-SNAP50_C PF12251.8 EGF76698.1 - 3.3e-51 173.8 0.3 4.6e-51 173.3 0.3 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal TIMELESS PF04821.14 EGF76699.1 - 6.4e-62 209.3 1.2 6.4e-62 209.3 1.2 2.3 2 0 0 2 2 2 2 Timeless protein Gtr1_RagA PF04670.12 EGF76699.1 - 0.048 13.0 0.2 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ETC_C1_NDUFA5 PF04716.14 EGF76700.1 - 8.8e-28 95.9 0.5 1.3e-27 95.4 0.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Mu-like_Pro PF10123.9 EGF76700.1 - 0.012 15.2 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein C-C_Bond_Lyase PF15617.6 EGF76701.1 - 0.19 10.8 0.0 0.21 10.7 0.0 1.0 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Peptidase_S9_N PF02897.15 EGF76702.1 - 5.4e-44 150.6 2.2 9.7e-44 149.8 2.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGF76702.1 - 1.7e-38 132.3 0.0 3.1e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AAA_18 PF13238.6 EGF76702.1 - 0.00045 20.8 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGF76702.1 - 0.0078 16.0 0.0 0.031 14.0 0.0 1.9 1 1 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 EGF76702.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGF76702.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pkinase PF00069.25 EGF76705.1 - 2.5e-23 82.8 0.0 5.8e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76705.1 - 4.1e-12 45.9 0.0 3.8e-10 39.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF76705.1 - 0.038 13.3 0.1 0.89 8.8 0.0 2.5 2 1 0 2 2 2 0 Kinase-like Pox_A_type_inc PF04508.12 EGF76705.1 - 0.086 12.7 1.6 0.21 11.5 1.6 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Aa_trans PF01490.18 EGF76706.1 - 7e-64 216.0 26.7 8.5e-64 215.8 26.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 EGF76707.1 - 2e-06 28.3 0.0 3.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGF76707.1 - 4.1e-05 23.1 0.0 5.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGF76707.1 - 0.0056 15.5 0.0 0.0064 15.3 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EGF76707.1 - 0.017 15.4 0.5 0.13 12.5 0.5 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EGF76708.1 - 4.9e-33 114.6 0.1 2.6e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EGF76708.1 - 2.3e-24 86.5 12.2 2.5e-24 86.4 11.6 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGF76708.1 - 8e-09 35.3 0.0 3.9e-05 23.2 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF76708.1 - 0.0008 19.3 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF76708.1 - 0.0015 18.2 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGF76708.1 - 0.0029 17.9 0.1 0.035 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGF76708.1 - 0.0032 17.2 0.2 0.04 13.7 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase SbcCD_C PF13558.6 EGF76708.1 - 0.0039 17.4 0.2 0.032 14.4 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EGF76708.1 - 0.011 16.1 0.1 0.029 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EGF76708.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGF76708.1 - 0.028 14.4 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGF76708.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGF76708.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 EGF76708.1 - 0.067 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 EGF76708.1 - 0.087 12.4 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGF76708.1 - 0.09 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 EGF76708.1 - 0.12 12.8 0.1 8.1 6.9 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGF76708.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Yos1 PF08571.10 EGF76709.1 - 6.4e-32 109.7 2.3 7.2e-32 109.5 2.3 1.0 1 0 0 1 1 1 1 Yos1-like ParcG PF10274.9 EGF76711.1 - 1.3e-82 276.4 0.0 1.6e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGF76711.1 - 0.005 16.5 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Svs_4_5_6 PF17381.2 EGF76711.1 - 0.12 13.4 0.0 0.17 12.9 0.0 1.3 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 Asp PF00026.23 EGF76712.1 - 4.6e-08 32.8 0.0 1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76712.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF76712.1 - 0.05 14.2 0.0 1 10.1 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease Usp PF00582.26 EGF76713.1 - 2.7e-24 86.3 0.1 3.2e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4246 PF14033.6 EGF76716.1 - 1.3e-28 100.3 0.0 1.7e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4444 PF14563.6 EGF76719.1 - 7.8 6.3 8.4 58 3.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4444) Trm112p PF03966.16 EGF76720.1 - 0.06 13.9 0.0 0.093 13.3 0.0 1.5 1 1 0 1 1 1 0 Trm112p-like protein AAA_14 PF13173.6 EGF76722.1 - 0.00021 21.3 0.0 0.93 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF4478 PF14793.6 EGF76722.1 - 0.02 14.8 0.5 0.53 10.2 0.1 2.8 3 0 0 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF5105 PF17118.5 EGF76724.1 - 0.039 13.7 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) DUF1275 PF06912.11 EGF76725.1 - 1.7e-24 86.9 17.8 4e-16 59.5 2.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1275) GPS2_interact PF15784.5 EGF76726.1 - 0.016 15.6 0.2 0.034 14.6 0.2 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DASH_Dad2 PF08654.10 EGF76726.1 - 0.2 12.1 3.5 0.42 11.1 0.8 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad2 WXG100 PF06013.12 EGF76726.1 - 0.22 11.8 3.3 3.3 8.0 0.3 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Keratin_2_head PF16208.5 EGF76726.1 - 0.28 11.3 15.3 0.43 10.7 11.1 2.4 2 0 0 2 2 2 0 Keratin type II head TLE_N PF03920.15 EGF76726.1 - 0.53 10.4 3.0 19 5.3 0.1 2.2 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain KRTAP PF11759.8 EGF76726.1 - 0.62 10.6 22.6 0.39 11.3 16.8 2.3 2 0 0 2 2 2 0 Keratin-associated matrix SSTK-IP PF15836.5 EGF76727.1 - 0.22 11.6 6.2 0.47 10.6 0.3 2.2 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Tom22 PF04281.13 EGF76729.1 - 3.9 7.3 6.8 1.1 9.0 2.2 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Sec2p PF06428.11 EGF76731.1 - 0.15 12.0 3.1 7.4 6.6 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF76731.1 - 0.79 9.9 5.0 19 5.4 5.1 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EGF76733.1 - 0.13 12.7 0.2 2.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MF_alpha_N PF05436.11 EGF76733.1 - 0.25 11.3 1.1 0.44 10.5 1.1 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Fib_alpha PF08702.10 EGF76733.1 - 0.26 11.5 4.4 0.51 10.5 0.4 2.3 1 1 1 2 2 1 0 Fibrinogen alpha/beta chain family TILa PF12714.7 EGF76735.1 - 0.044 13.8 4.0 1.1 9.3 0.4 2.1 2 0 0 2 2 2 0 TILa domain Hid1 PF12722.7 EGF76736.1 - 0.92 7.6 10.0 1.4 7.0 10.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XRCC4 PF06632.12 EGF76736.1 - 5.8 5.7 8.7 2.8 6.7 6.4 1.6 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CAML PF14963.6 EGF76736.1 - 9.2 6.3 7.3 1.3 9.1 3.4 1.6 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Erp_C PF06780.11 EGF76737.1 - 0.0032 17.5 0.6 0.0049 16.9 0.6 1.3 1 0 0 1 1 1 1 Erp protein C-terminus Spc7 PF08317.11 EGF76737.1 - 0.017 14.0 1.5 0.026 13.4 1.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MetOD2 PF18548.1 EGF76737.1 - 0.022 14.9 2.0 0.067 13.3 1.8 1.9 1 1 0 1 1 1 0 Metanogen output domain 2 TMF_DNA_bd PF12329.8 EGF76737.1 - 1.2 9.2 7.4 0.59 10.2 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_22 PF13401.6 EGF76740.1 - 0.031 14.6 0.0 0.098 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhetRS_B1 PF18262.1 EGF76742.1 - 0.043 14.0 0.4 0.63 10.3 0.1 2.4 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain FAM76 PF16046.5 EGF76742.1 - 0.14 11.5 10.2 0.2 11.0 10.2 1.2 1 0 0 1 1 1 0 FAM76 protein Uds1 PF15456.6 EGF76742.1 - 5.1 7.3 7.3 1 9.5 0.3 2.4 2 1 0 2 2 2 0 Up-regulated During Septation PCI PF01399.27 EGF76743.1 - 0.65 10.5 3.1 1.2 9.6 3.1 1.5 1 1 0 1 1 1 0 PCI domain Piwi PF02171.17 EGF76744.1 - 5.5e-83 278.7 0.1 8e-83 278.1 0.1 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EGF76744.1 - 2.1e-16 59.3 0.0 5.9e-16 57.9 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EGF76744.1 - 3.1e-13 49.8 0.0 8.3e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 EGF76744.1 - 1.3e-12 48.5 0.0 3.7e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 EGF76744.1 - 6.3e-09 35.8 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGF76744.1 - 0.024 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 Mid domain of argonaute FoP_duplication PF13865.6 EGF76744.1 - 3.7 8.1 8.1 9.3 6.9 8.1 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Chitin_synth_2 PF03142.15 EGF76745.1 - 6.7e-230 764.2 1.5 8e-230 763.9 1.5 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGF76745.1 - 4e-13 49.8 0.1 1.2e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF76745.1 - 4.3e-13 49.6 11.4 2e-12 47.4 11.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGF76745.1 - 4.2e-07 29.6 0.0 2.8e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF76745.1 - 0.00021 21.1 0.0 0.029 14.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 KH_1 PF00013.29 EGF76748.1 - 2.2e-83 274.0 18.7 2.3e-10 40.1 0.7 13.6 13 1 0 13 13 13 11 KH domain KH_2 PF07650.17 EGF76748.1 - 1e-08 34.9 12.3 0.45 10.4 0.0 7.5 6 1 1 7 7 7 4 KH domain SLS PF14611.6 EGF76748.1 - 0.00012 22.0 20.6 0.049 13.5 0.8 6.5 4 2 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator RRP7 PF12923.7 EGF76748.1 - 0.0036 17.4 2.8 0.55 10.4 0.4 2.9 2 0 0 2 2 2 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain KH_4 PF13083.6 EGF76748.1 - 0.022 14.6 4.2 37 4.3 0.1 5.5 4 0 0 4 4 4 0 KH domain DUF2067 PF09840.9 EGF76748.1 - 0.062 12.9 0.7 3.6 7.1 0.0 3.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) Terminase_4 PF05119.12 EGF76748.1 - 0.14 12.6 0.1 1.7 9.1 0.0 3.0 2 0 0 2 2 2 0 Phage terminase, small subunit zf-C2H2_2 PF12756.7 EGF76749.1 - 7.1e-33 113.0 24.6 2e-27 95.5 4.3 3.6 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGF76749.1 - 1.8e-07 31.3 4.2 1.2e-05 25.5 1.8 4.1 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF76749.1 - 6.9e-06 26.3 3.5 6.9e-06 26.3 3.5 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGF76749.1 - 2.9e-05 24.3 5.9 0.089 13.3 1.0 3.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGF76749.1 - 0.0082 16.1 11.7 0.26 11.3 0.1 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGF76749.1 - 0.063 14.1 0.3 0.063 14.1 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger YjbH PF06082.11 EGF76749.1 - 0.21 10.4 2.4 0.34 9.7 2.4 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Gp-FAR-1 PF05823.12 EGF76749.1 - 0.21 11.9 4.2 0.54 10.6 1.3 2.2 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Lar_restr_allev PF14354.6 EGF76749.1 - 1.7 9.1 7.1 26 5.3 0.0 3.6 4 0 0 4 4 4 0 Restriction alleviation protein Lar Cofilin_ADF PF00241.20 EGF76750.1 - 1.4e-33 115.3 0.0 1.5e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Plk4_PB1 PF18190.1 EGF76750.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 Clr2 PF10383.9 EGF76751.1 - 0.006 17.4 0.0 0.26 12.0 0.0 3.2 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 IQ PF00612.27 EGF76752.1 - 7.2e-16 56.4 18.2 1.5e-05 24.3 2.4 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif BRE1 PF08647.11 EGF76753.1 - 8.9e-07 28.9 39.3 9.4e-07 28.8 12.8 4.0 3 2 1 4 4 4 2 BRE1 E3 ubiquitin ligase Choline_kinase PF01633.20 EGF76753.1 - 0.19 11.3 8.7 0.12 12.0 0.7 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase DASH_Duo1 PF08651.10 EGF76753.1 - 1.9 8.4 12.1 1.1 9.0 2.5 3.6 3 1 0 3 3 3 0 DASH complex subunit Duo1 V_ATPase_I PF01496.19 EGF76753.1 - 4.8 5.0 28.4 0.12 10.2 11.4 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.11 EGF76753.1 - 8.2 7.1 15.5 0.28 11.7 2.8 3.4 3 1 1 4 4 4 0 Syntaxin 6, N-terminal GST_N PF02798.20 EGF76754.1 - 1.2e-15 57.6 0.0 2.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGF76754.1 - 1.1e-14 54.6 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGF76754.1 - 2.2e-11 43.9 0.0 4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF76754.1 - 1.5e-08 34.7 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGF76754.1 - 6e-07 29.6 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGF76754.1 - 8.5e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATG22 PF11700.8 EGF76755.1 - 4.4e-84 282.8 18.2 8.7e-84 281.8 18.2 1.5 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4131 PF13567.6 EGF76755.1 - 0.26 10.9 0.0 0.26 10.9 0.0 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) CDC45 PF02724.14 EGF76756.1 - 2.1e-191 637.5 0.0 2.4e-191 637.3 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein IFT57 PF10498.9 EGF76756.1 - 0.33 9.9 4.1 0.5 9.3 4.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PX PF00787.24 EGF76758.1 - 6.3e-10 39.0 0.0 8.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 PX domain SIR2 PF02146.17 EGF76759.1 - 1.6e-33 116.1 0.0 1.7e-31 109.5 0.0 2.1 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGF76759.1 - 0.078 12.7 0.1 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain LRR_4 PF12799.7 EGF76760.1 - 5e-06 26.8 6.7 9.4e-05 22.7 0.5 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF76760.1 - 2.4e-05 24.0 7.4 0.00011 21.9 1.1 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 EGF76760.1 - 0.00062 20.0 8.0 1.8 9.4 0.3 4.5 5 0 0 5 5 5 2 Leucine Rich Repeat RIFIN PF02009.16 EGF76760.1 - 0.0046 16.9 0.0 0.0067 16.4 0.0 1.1 1 0 0 1 1 1 1 Rifin Adeno_E3_CR2 PF02439.15 EGF76760.1 - 0.27 11.0 5.0 0.56 10.0 5.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Acetyltransf_10 PF13673.7 EGF76761.1 - 1.5e-08 34.6 0.0 4.7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF76761.1 - 2e-05 24.9 0.0 2.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF76761.1 - 2.4e-05 24.5 0.0 3.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGF76761.1 - 0.00053 19.9 0.0 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein HSP20 PF00011.21 EGF76762.1 - 1.8e-09 37.6 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGF76762.1 - 2.3e-05 23.9 0.0 4.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA PIN7 PF18475.1 EGF76762.1 - 0.018 15.7 0.0 0.052 14.2 0.0 1.7 1 0 0 1 1 1 0 PIN domain Apc15p PF05841.11 EGF76762.1 - 7.7 7.3 6.9 10 7.0 0.0 2.3 1 1 1 2 2 2 0 Apc15p protein Pro_isomerase PF00160.21 EGF76763.1 - 2e-49 167.9 0.0 4.3e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGF76763.1 - 7.7e-08 32.9 0.4 1.3 10.0 0.0 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.11 EGF76763.1 - 0.0032 17.4 0.1 3.1 7.6 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A BAG PF02179.16 EGF76764.1 - 8.2e-13 48.6 0.1 1.3e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 BAG domain DUF1674 PF07896.12 EGF76765.1 - 1.6e-22 79.7 2.8 3.1e-22 78.8 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) MRP-L47 PF06984.13 EGF76766.1 - 5.9e-26 90.4 1.0 1.2e-25 89.5 1.0 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EGF76766.1 - 0.058 13.4 1.4 1.4 9.0 0.3 3.0 2 1 0 2 2 2 0 Ribosomal L29 protein RFXA_RFXANK_bdg PF15289.6 EGF76766.1 - 0.77 10.1 10.1 4 7.8 3.6 2.6 2 1 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Nuf2 PF03800.14 EGF76767.1 - 8.3e-39 132.9 0.0 8.3e-39 132.9 0.0 2.2 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EGF76767.1 - 2.2e-23 82.5 22.7 2.2e-23 82.5 22.7 4.0 1 1 3 4 4 4 2 Designed helical repeat protein 10 domain ATG16 PF08614.11 EGF76767.1 - 0.085 13.1 46.6 2.4 8.3 16.0 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EGF76767.1 - 1 8.2 46.2 2.8 6.7 28.3 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EGF76767.1 - 3.5 6.9 50.1 2.1 7.6 23.1 3.4 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EGF76768.1 - 0.0034 17.0 5.0 0.0043 16.7 5.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein FAM76 PF16046.5 EGF76768.1 - 0.004 16.6 0.2 0.0047 16.3 0.2 1.1 1 0 0 1 1 1 1 FAM76 protein Atg14 PF10186.9 EGF76768.1 - 0.0085 15.2 3.6 0.011 14.8 3.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 KELK PF15796.5 EGF76768.1 - 0.011 16.2 5.8 0.016 15.7 5.8 1.2 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3584 PF12128.8 EGF76768.1 - 0.015 12.9 1.6 0.018 12.6 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mod_r PF07200.13 EGF76768.1 - 0.016 15.4 2.7 0.021 14.9 2.7 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FliJ PF02050.16 EGF76768.1 - 0.042 14.1 3.6 0.046 13.9 1.8 1.8 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4201 PF13870.6 EGF76768.1 - 0.056 13.2 8.8 0.073 12.8 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4618 PF15397.6 EGF76768.1 - 0.064 12.7 4.4 0.16 11.4 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TMPIT PF07851.13 EGF76768.1 - 0.086 12.1 1.4 0.11 11.7 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DHR10 PF18595.1 EGF76768.1 - 0.096 12.7 6.7 0.24 11.4 6.2 1.8 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain UPF0242 PF06785.11 EGF76768.1 - 0.15 12.1 2.3 0.22 11.6 2.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EGF76768.1 - 0.22 12.2 3.3 0.54 10.9 0.6 2.2 1 1 1 2 2 2 0 SlyX Fib_alpha PF08702.10 EGF76768.1 - 0.38 10.9 3.2 0.38 11.0 0.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 EGF76768.1 - 0.44 10.6 7.8 1 9.4 3.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EGF76768.1 - 0.71 9.9 3.9 3.4 7.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EGF76768.1 - 0.81 9.5 5.5 0.77 9.6 0.6 2.1 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 EGF76768.1 - 1.7 8.9 8.1 1.7 8.9 2.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EGF76768.1 - 3.5 8.2 7.2 18 5.9 7.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB DUF16 PF01519.16 EGF76769.1 - 0.0009 19.7 1.2 0.0013 19.1 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF16 Atg14 PF10186.9 EGF76769.1 - 0.0013 17.9 4.3 0.0018 17.4 4.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EGF76769.1 - 0.0017 18.5 6.6 0.0024 18.0 6.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 EGF76769.1 - 0.002 17.1 0.2 0.0023 16.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AKNA PF12443.8 EGF76769.1 - 0.0027 18.3 1.1 0.0027 18.3 1.1 2.4 2 1 1 3 3 2 1 AT-hook-containing transcription factor CorA PF01544.18 EGF76769.1 - 0.0085 15.4 1.3 0.011 15.1 1.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SlyX PF04102.12 EGF76769.1 - 0.0087 16.7 2.2 0.29 11.8 0.1 2.3 1 1 1 2 2 2 1 SlyX FAM76 PF16046.5 EGF76769.1 - 0.0094 15.3 0.5 0.011 15.1 0.5 1.2 1 0 0 1 1 1 1 FAM76 protein DUF4201 PF13870.6 EGF76769.1 - 0.015 15.1 6.9 0.028 14.2 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Filament PF00038.21 EGF76769.1 - 0.017 14.7 3.3 0.021 14.4 3.3 1.1 1 0 0 1 1 1 0 Intermediate filament protein FliJ PF02050.16 EGF76769.1 - 0.019 15.2 3.4 0.19 12.0 0.2 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4618 PF15397.6 EGF76769.1 - 0.021 14.3 0.8 0.021 14.3 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EGF76769.1 - 0.026 14.9 3.8 0.026 14.9 3.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Phage_HK97_TLTM PF06120.11 EGF76769.1 - 0.034 13.3 1.2 0.045 12.9 1.2 1.1 1 0 0 1 1 1 0 Tail length tape measure protein VPS38 PF17649.1 EGF76769.1 - 0.039 12.8 1.4 0.048 12.5 1.4 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 APG6_N PF17675.1 EGF76769.1 - 0.045 14.3 2.6 0.062 13.8 2.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3558 PF12079.8 EGF76769.1 - 0.046 13.7 0.4 0.071 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Exonuc_VII_L PF02601.15 EGF76769.1 - 0.048 13.2 0.4 0.051 13.1 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF773 PF05600.12 EGF76769.1 - 0.051 12.3 3.2 0.067 11.9 3.2 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 TcdB_N PF12918.7 EGF76769.1 - 0.051 13.9 1.5 0.11 12.8 1.5 1.7 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain TMPIT PF07851.13 EGF76769.1 - 0.061 12.6 1.9 0.088 12.0 1.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein EzrA PF06160.12 EGF76769.1 - 0.061 11.5 3.8 0.077 11.2 3.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HAP1_N PF04849.13 EGF76769.1 - 0.067 12.4 2.9 0.089 12.0 2.9 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 EGF76769.1 - 0.068 12.0 3.3 0.1 11.5 3.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Med12 PF09497.10 EGF76769.1 - 0.093 13.0 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Transcription mediator complex subunit Med12 IFN-gamma PF00714.17 EGF76769.1 - 0.11 12.4 0.2 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Interferon gamma FlaC_arch PF05377.11 EGF76769.1 - 0.14 12.6 0.7 0.14 12.6 0.7 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) USP8_interact PF08941.10 EGF76769.1 - 0.15 11.9 1.1 0.25 11.1 0.9 1.4 1 1 1 2 2 2 0 USP8 interacting YabA PF06156.13 EGF76769.1 - 0.2 12.3 2.8 1.1 9.9 0.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 EGF76769.1 - 0.23 11.3 2.0 0.31 10.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EGF76769.1 - 0.29 11.2 7.9 0.078 13.1 2.6 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EGF76769.1 - 0.31 10.8 6.8 0.076 12.8 1.4 2.1 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 EGF76769.1 - 0.35 11.2 3.9 0.21 11.9 0.8 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 P4Ha_N PF08336.11 EGF76769.1 - 0.7 9.9 4.7 4.7 7.2 4.6 1.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KxDL PF10241.9 EGF76769.1 - 0.81 10.0 4.3 0.65 10.3 1.7 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein ATG16 PF08614.11 EGF76769.1 - 0.89 9.7 9.5 0.065 13.5 1.5 2.2 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 EGF76769.1 - 1 9.6 6.8 2.6 8.3 4.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DHR10 PF18595.1 EGF76769.1 - 1.5 8.9 8.3 0.76 9.9 2.7 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 EGF76769.1 - 2.2 8.3 9.2 0.79 9.8 4.9 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 EGF76770.1 - 0.0019 17.9 6.8 0.0025 17.6 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Arm-DNA-bind_5 PF17293.2 EGF76770.1 - 0.0026 18.1 2.3 0.0029 18.0 0.7 1.8 1 1 1 2 2 2 1 Arm DNA-binding domain VPS38 PF17649.1 EGF76770.1 - 0.016 14.1 2.1 0.02 13.8 2.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DUF773 PF05600.12 EGF76770.1 - 0.017 13.9 2.1 0.022 13.5 2.1 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF3584 PF12128.8 EGF76770.1 - 0.017 12.7 1.5 0.021 12.4 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 EGF76770.1 - 0.034 14.7 1.0 0.046 14.3 1.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF16 PF01519.16 EGF76770.1 - 0.034 14.6 0.6 0.049 14.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 HAP1_N PF04849.13 EGF76770.1 - 0.037 13.2 1.1 0.049 12.8 1.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Atg14 PF10186.9 EGF76770.1 - 0.041 13.0 4.2 0.054 12.6 4.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 EGF76770.1 - 0.081 12.2 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 EGF76770.1 - 0.086 10.8 1.0 0.11 10.4 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med12 PF09497.10 EGF76770.1 - 0.089 13.1 0.1 1.6 9.1 0.0 2.4 2 1 0 2 2 2 0 Transcription mediator complex subunit Med12 FliJ PF02050.16 EGF76770.1 - 0.095 12.9 3.7 0.82 9.9 0.3 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein TMF_TATA_bd PF12325.8 EGF76770.1 - 0.097 12.9 4.8 4.3 7.6 4.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 EGF76770.1 - 0.15 11.3 1.2 0.22 10.7 1.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 EGF76770.1 - 0.16 12.1 6.0 0.22 11.6 6.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 EGF76770.1 - 0.21 11.6 6.1 0.27 11.3 1.3 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 EGF76770.1 - 0.28 11.8 2.1 11 6.7 0.1 2.3 1 1 1 2 2 2 0 SlyX YabA PF06156.13 EGF76770.1 - 0.35 11.5 2.1 1.2 9.8 0.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA FliD_N PF02465.18 EGF76770.1 - 0.73 10.6 10.1 0.42 11.3 2.5 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.15 EGF76770.1 - 0.81 9.5 5.5 0.35 10.7 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 EGF76770.1 - 0.87 9.6 7.7 0.42 10.7 3.9 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 EGF76770.1 - 1.5 9.2 6.1 4.5 7.7 6.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 EGF76771.1 - 0.0002 21.9 8.8 0.00027 21.5 8.8 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region PHM7_cyt PF14703.6 EGF76771.1 - 0.022 15.0 4.9 0.022 15.0 4.9 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CDPS PF16715.5 EGF76771.1 - 0.042 13.5 0.5 0.059 13.0 0.5 1.3 1 0 0 1 1 1 0 Cyclodipeptide synthase Muted PF14942.6 EGF76771.1 - 0.15 12.4 10.0 0.081 13.3 6.4 1.9 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ADIP PF11559.8 EGF76771.1 - 0.21 11.6 14.3 0.41 10.7 9.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Vfa1 PF08432.10 EGF76771.1 - 0.56 10.5 20.9 0.1 13.0 10.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MIF4G_like_2 PF09090.11 EGF76771.1 - 2.3 7.6 8.3 0.44 10.0 4.9 1.4 2 0 0 2 2 2 0 MIF4G like DASH_Spc19 PF08287.11 EGF76771.1 - 3.2 7.6 15.2 0.31 10.9 8.0 2.1 2 0 0 2 2 2 0 Spc19 YabA PF06156.13 EGF76771.1 - 3.3 8.4 11.6 0.25 12.0 6.7 1.6 2 0 0 2 2 2 0 Initiation control protein YabA Ax_dynein_light PF10211.9 EGF76771.1 - 5.5 6.9 14.5 1.4 8.8 10.3 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain DUF773 PF05600.12 EGF76772.1 - 0.006 15.4 2.6 0.006 15.4 2.6 1.4 2 0 0 2 2 2 1 CDK5 regulatory subunit-associated protein 3 ORC6 PF05460.13 EGF76772.1 - 3.4 6.8 9.1 0.15 11.3 2.4 1.7 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Npa1 PF11707.8 EGF76773.1 - 0.0019 17.7 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal PPR PF01535.20 EGF76773.1 - 0.0045 17.2 3.6 15 6.1 0.0 6.3 7 0 0 7 7 7 1 PPR repeat SPOB_a PF14689.6 EGF76773.1 - 0.022 14.4 2.2 35 4.2 0.0 4.8 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain PPR_2 PF13041.6 EGF76773.1 - 0.058 13.6 0.1 59 4.0 0.0 4.1 3 1 1 4 4 4 0 PPR repeat family DUF1084 PF06454.11 EGF76774.1 - 0.00027 20.4 12.7 0.00044 19.7 12.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.13 EGF76774.1 - 0.058 13.8 7.3 0.15 12.4 7.3 1.7 1 0 0 1 1 1 0 EGF-like domain UPF0223 PF05256.12 EGF76775.1 - 0.065 13.6 3.7 0.35 11.3 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) DUF4407 PF14362.6 EGF76775.1 - 0.25 10.7 1.1 0.27 10.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EGF76775.1 - 1.1 9.6 6.5 1.7 9.0 6.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) mRNA_cap_enzyme PF01331.19 EGF76776.1 - 0.0032 17.3 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DUF4771 PF15995.5 EGF76776.1 - 0.095 13.0 1.1 0.26 11.5 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4771) DUF4820 PF16091.5 EGF76776.1 - 0.33 10.3 3.0 0.17 11.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Dynein_light PF01221.18 EGF76776.1 - 0.47 10.8 2.5 6.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Dynein light chain type 1 Pkinase PF00069.25 EGF76777.1 - 2.4e-29 102.5 0.0 7.1e-15 55.1 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76777.1 - 1.3e-15 57.4 0.0 1.2e-08 34.5 0.0 4.5 4 1 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.6 EGF76777.1 - 0.11 11.8 0.0 9.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RNase_H PF00075.24 EGF76779.1 - 1.7e-38 132.0 0.1 2.4e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGF76779.1 - 0.0034 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Herpes_UL25 PF01499.16 EGF76779.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family PPR_2 PF13041.6 EGF76780.1 - 3.5e-48 161.6 12.6 4.1e-11 42.9 0.6 10.8 6 3 5 11 11 11 9 PPR repeat family PPR PF01535.20 EGF76780.1 - 1.7e-29 100.0 13.1 5.1e-05 23.3 0.1 11.8 12 0 0 12 12 12 7 PPR repeat PPR_3 PF13812.6 EGF76780.1 - 3.6e-28 97.4 5.2 7.2e-06 26.0 0.6 8.7 7 2 2 9 9 9 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF76780.1 - 2e-22 78.6 4.3 0.0085 15.8 0.1 9.8 10 0 0 10 10 10 7 PPR repeat PPR_long PF17177.4 EGF76780.1 - 1.2e-15 57.5 0.2 2.3e-06 27.1 0.1 5.7 4 1 0 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_10 PF13374.6 EGF76780.1 - 6.9e-05 22.6 6.5 0.83 9.6 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat RPM2 PF08579.11 EGF76780.1 - 0.00011 22.5 4.8 0.44 10.9 0.6 5.2 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 EGF76780.1 - 0.0012 19.5 0.0 1.1e+02 4.1 0.0 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF76780.1 - 0.0033 17.9 0.0 0.52 10.9 0.0 3.5 5 0 0 5 5 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76780.1 - 0.0049 16.9 5.0 17 5.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EGF76780.1 - 0.041 14.3 1.2 1.8e+02 2.5 0.0 4.8 5 0 0 5 5 5 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 EGF76780.1 - 0.14 12.5 3.3 64 4.0 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF76780.1 - 0.61 10.0 5.0 85 3.2 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76780.1 - 0.72 10.0 9.4 6 7.1 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Pkinase PF00069.25 EGF76781.1 - 2.2e-40 138.7 0.0 2.4e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76781.1 - 1.1e-20 74.1 0.0 1.3e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF76781.1 - 0.00029 20.2 0.0 0.00047 19.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF76781.1 - 0.0045 15.8 0.0 0.0054 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF76781.1 - 0.006 16.5 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF76781.1 - 0.092 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EGF76781.1 - 0.1 12.0 0.4 0.19 11.0 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF76781.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DivIC PF04977.15 EGF76782.1 - 0.014 15.1 3.9 0.48 10.2 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator GM_CSF PF01109.17 EGF76782.1 - 0.021 14.9 0.6 7.2 6.8 0.1 2.4 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor YabA PF06156.13 EGF76782.1 - 0.04 14.6 2.7 0.81 10.4 0.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 EGF76782.1 - 0.048 14.3 1.7 0.1 13.2 1.6 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Arfaptin PF06456.13 EGF76782.1 - 0.08 12.5 2.4 0.46 10.0 0.1 2.0 1 1 1 2 2 2 0 Arfaptin-like domain Atg14 PF10186.9 EGF76782.1 - 0.097 11.7 2.0 0.13 11.3 2.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 EGF76782.1 - 0.12 12.8 1.7 0.86 10.0 0.2 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper BRE1 PF08647.11 EGF76782.1 - 0.25 11.5 6.1 0.31 11.2 4.6 1.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TSC22 PF01166.18 EGF76782.1 - 0.38 11.1 2.0 9.1 6.7 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 EGF76782.1 - 0.44 10.8 5.0 2.6 8.3 1.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EGF76782.1 - 0.45 9.8 6.6 1.3 8.4 6.6 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3446 PF11928.8 EGF76782.1 - 1.7 9.0 9.1 2 8.8 7.5 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain bZIP_1 PF00170.21 EGF76782.1 - 4.6 7.4 6.9 16 5.7 0.8 2.5 2 1 0 2 2 2 0 bZIP transcription factor DUF4246 PF14033.6 EGF76784.1 - 1.5e-29 103.4 0.0 2.2e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) P21-Arc PF04062.14 EGF76784.1 - 0.046 13.8 0.1 0.059 13.4 0.1 1.1 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit PMC2NT PF08066.12 EGF76786.1 - 0.038 14.7 1.2 0.39 11.4 0.2 2.8 1 1 1 2 2 2 0 PMC2NT (NUC016) domain EpuA PF11772.8 EGF76786.1 - 2.6 7.8 3.6 22 4.8 0.1 3.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase subunit beta CLASP_N PF12348.8 EGF76787.1 - 1.3e-49 168.9 1.4 2.1e-49 168.1 0.8 1.7 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EGF76787.1 - 0.026 14.7 0.4 17 6.0 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat ABC_tran PF00005.27 EGF76788.1 - 1.4e-53 181.0 0.3 2.8e-32 112.1 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGF76788.1 - 1.7e-42 145.9 39.8 1.1e-27 97.4 19.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGF76788.1 - 8e-09 35.3 9.3 0.003 17.0 0.7 4.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF76788.1 - 2.5e-06 27.5 3.3 0.035 14.2 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGF76788.1 - 6.5e-06 25.8 1.6 0.058 13.1 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF76788.1 - 4.8e-05 23.3 4.7 0.11 12.2 0.0 3.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EGF76788.1 - 5.3e-05 23.4 4.3 0.0021 18.2 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EGF76788.1 - 0.00074 18.9 0.2 0.81 9.0 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EGF76788.1 - 0.0016 18.3 0.0 0.9 9.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGF76788.1 - 0.0019 18.3 5.8 0.045 13.8 2.7 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 EGF76788.1 - 0.0071 15.7 0.7 0.57 9.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EGF76788.1 - 0.014 15.1 0.5 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGF76788.1 - 0.02 15.2 0.2 2.3 8.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EGF76788.1 - 0.024 14.2 0.3 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EGF76788.1 - 0.024 14.6 0.6 9.5 6.1 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 EGF76788.1 - 0.031 14.5 0.3 10 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EGF76788.1 - 0.035 13.7 0.0 8.9 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGF76788.1 - 0.036 13.6 1.0 6 6.4 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGF76788.1 - 0.038 14.4 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGF76788.1 - 0.042 14.3 0.3 2 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGF76788.1 - 0.044 13.6 3.5 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 EGF76788.1 - 0.059 13.3 0.4 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 T2SSE PF00437.20 EGF76788.1 - 0.059 12.4 0.3 3.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 EGF76788.1 - 0.076 12.7 0.2 4 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 EGF76788.1 - 0.081 11.9 1.1 4.7 6.1 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 EGF76788.1 - 0.21 10.6 1.5 1.8 7.6 0.2 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DEAD PF00270.29 EGF76788.1 - 0.24 11.1 2.6 1.5 8.6 0.5 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 EGF76788.1 - 0.25 10.2 1.0 3.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EGF76788.1 - 0.76 10.1 6.3 17 5.7 0.7 3.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGF76788.1 - 2.3 8.4 3.7 19 5.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain IFT46_B_C PF12317.8 EGF76789.1 - 5.7e-79 264.8 0.7 7.9e-79 264.3 0.7 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal NAPRTase PF04095.16 EGF76790.1 - 8.2e-38 130.4 0.0 1.2e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 EGF76790.1 - 1e-16 61.2 0.2 2.5e-16 59.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) NAPRTase_N PF17767.1 EGF76790.1 - 0.024 15.0 0.3 0.049 14.0 0.3 1.6 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Prefoldin_2 PF01920.20 EGF76791.1 - 8.6e-06 25.7 0.3 1.8e-05 24.7 0.2 1.6 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EGF76791.1 - 0.00042 20.2 0.2 0.00078 19.4 0.1 1.5 1 1 0 1 1 1 1 Prefoldin subunit SCAB_CC PF16712.5 EGF76791.1 - 0.026 14.4 0.2 0.038 13.8 0.1 1.3 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Fer4_12 PF13353.6 EGF76791.1 - 0.049 13.9 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Bcr-Abl_Oligo PF09036.10 EGF76791.1 - 0.067 13.2 1.3 0.16 12.0 0.1 2.1 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Mito_carr PF00153.27 EGF76792.1 - 3.7e-54 180.6 4.1 1.6e-18 66.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein PUL PF08324.11 EGF76793.1 - 8.2e-53 179.4 5.8 1.1e-52 179.0 5.8 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGF76793.1 - 1.1e-42 144.8 0.5 2.3e-42 143.8 0.5 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGF76793.1 - 8.6e-34 115.0 16.0 4.5e-06 27.3 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGF76793.1 - 3.9e-06 26.8 0.1 0.0035 17.4 0.0 3.6 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PDH PF02153.17 EGF76794.1 - 1.2e-19 70.4 0.1 1.8e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EGF76794.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cpn60_TCP1 PF00118.24 EGF76795.1 - 4.8e-87 292.6 3.4 1.5e-86 291.0 3.4 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FAD-oxidase_C PF02913.19 EGF76796.1 - 1.1e-59 202.1 0.0 1.7e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGF76796.1 - 1.8e-36 124.9 0.6 3.5e-36 124.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain DUF2750 PF11042.8 EGF76796.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) Chitin_synth_1 PF01644.17 EGF76797.1 - 9e-72 240.4 1.4 1.4e-71 239.7 1.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EGF76797.1 - 2.8e-24 85.6 1.4 4.2e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 EGF76797.1 - 3.8e-22 78.0 0.0 8.5e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EGF76797.1 - 1.2e-06 28.5 13.8 1.7e-06 28.1 10.7 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF76797.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CPSase_L_D2 PF02786.17 EGF76798.1 - 4.7e-76 255.0 0.0 7.5e-76 254.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGF76798.1 - 9.8e-46 154.8 0.1 9.1e-45 151.7 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGF76798.1 - 1.9e-35 121.2 0.0 3.6e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGF76798.1 - 1.7e-17 63.0 2.7 4e-17 61.8 1.8 2.1 3 0 0 3 3 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGF76798.1 - 8.5e-12 45.0 0.1 4.7e-11 42.6 0.1 2.1 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGF76798.1 - 6.9e-09 35.5 0.1 2.6e-08 33.7 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGF76798.1 - 4.8e-07 29.5 0.4 0.0017 18.1 0.0 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EGF76798.1 - 1e-05 25.7 0.2 3.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EGF76798.1 - 7.5e-05 22.6 0.1 0.00043 20.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 EGF76798.1 - 0.0014 19.3 0.0 4.1 8.1 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EGF76798.1 - 0.0033 16.7 0.0 1.8 7.7 0.0 2.7 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 EGF76798.1 - 0.0044 16.6 0.0 0.025 14.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.11 EGF76798.1 - 0.031 13.7 0.2 0.058 12.8 0.2 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 EGF76798.1 - 0.031 14.2 0.1 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 EGF76798.1 - 0.047 12.9 0.1 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Solute_trans_a PF03619.16 EGF76799.1 - 9.8e-80 267.9 22.8 1.2e-79 267.6 22.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TPR_12 PF13424.6 EGF76800.1 - 5e-07 29.9 2.7 0.00017 21.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF76800.1 - 8.4e-06 25.4 2.3 0.11 12.4 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGF76800.1 - 0.00021 21.7 1.2 0.056 14.1 0.4 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76800.1 - 0.00023 21.0 2.6 0.026 14.6 0.5 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Nairovirus_M PF07948.11 EGF76800.1 - 0.04 12.2 0.3 0.072 11.3 0.3 1.3 1 0 0 1 1 1 0 Nairovirus M polyprotein-like TPR_7 PF13176.6 EGF76800.1 - 0.045 13.8 0.3 0.35 11.0 0.3 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF76800.1 - 0.048 14.5 0.1 13 6.9 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PfUIS3 PF11567.8 EGF76800.1 - 0.11 12.9 1.3 24 5.3 0.2 3.0 3 0 0 3 3 3 0 Plasmodium falciparum UIS3 membrane protein TPR_8 PF13181.6 EGF76800.1 - 1.2 9.5 5.9 0.54 10.6 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3719 PF12516.8 EGF76802.1 - 1.4e-07 31.1 0.0 5e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) CAGE1 PF15066.6 EGF76802.1 - 0.13 10.9 2.3 0.12 11.1 0.4 1.7 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family Rad51 PF08423.11 EGF76803.1 - 3e-13 49.6 0.3 3.1e-13 49.6 0.3 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGF76803.1 - 6.5e-07 29.1 0.1 6.5e-07 29.1 0.1 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EGF76803.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGF76803.1 - 0.018 14.4 0.1 0.019 14.3 0.1 1.0 1 0 0 1 1 1 0 KaiC PDEase_I PF00233.19 EGF76804.1 - 6.8e-71 238.7 7.0 4.6e-70 236.0 7.0 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF1676 PF07898.13 EGF76804.1 - 0.035 14.1 0.5 0.071 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF987 PF06174.11 EGF76806.1 - 0.14 12.1 0.3 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF987) DUF3888 PF13027.6 EGF76808.1 - 0.015 15.7 0.8 0.015 15.7 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3888) RNase_H_2 PF13482.6 EGF76808.1 - 0.029 14.3 5.8 0.035 14.1 1.1 2.7 2 1 1 3 3 3 0 RNase_H superfamily BTB_3 PF16017.5 EGF76808.1 - 0.033 14.3 0.1 0.07 13.2 0.1 1.7 1 1 0 1 1 1 0 BTB/POZ domain zf-RING_7 PF02591.15 EGF76808.1 - 0.08 13.1 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain CBM49 PF09478.10 EGF76810.1 - 0.03 14.6 3.6 9.9 6.6 0.5 3.5 3 0 0 3 3 3 0 Carbohydrate binding domain CBM49 UBA PF00627.31 EGF76811.1 - 4.2e-09 36.1 0.0 4.2e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 EGF76811.1 - 1.1e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 EGF76811.1 - 0.0025 17.7 33.3 0.0092 15.9 10.9 4.2 3 1 1 4 4 4 2 STI1 domain RPN13_C PF16550.5 EGF76811.1 - 0.019 15.1 0.3 0.035 14.3 0.3 1.4 1 0 0 1 1 1 0 UCH-binding domain CytochromB561_N PF09786.9 EGF76812.1 - 4.1e-32 111.9 2.4 3.5e-31 108.9 2.4 2.2 1 1 0 1 1 1 1 Cytochrome B561, N terminal Amelogenin PF02948.15 EGF76812.1 - 0.028 15.1 0.2 0.071 13.8 0.2 1.6 1 0 0 1 1 1 0 Amelogenin ThrE PF06738.12 EGF76812.1 - 0.13 11.6 0.7 0.25 10.7 0.7 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter PDEase_I PF00233.19 EGF76813.1 - 2.8e-80 269.5 0.4 8.4e-80 267.9 0.0 1.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Ras PF00071.22 EGF76814.1 - 2e-57 193.3 0.0 2.4e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF76814.1 - 2.5e-35 121.3 0.0 3.5e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF76814.1 - 2.3e-14 53.2 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF76814.1 - 4e-05 23.7 0.0 6.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF76814.1 - 0.00041 19.8 0.0 0.00056 19.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGF76814.1 - 0.00077 19.9 0.0 0.0011 19.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGF76814.1 - 0.0028 17.6 0.2 0.84 9.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGF76814.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DivIC PF04977.15 EGF76815.1 - 0.003 17.3 6.2 0.02 14.7 6.0 2.0 1 1 1 2 2 2 1 Septum formation initiator PDCD2_C PF04194.13 EGF76815.1 - 0.0038 17.3 0.1 0.006 16.7 0.1 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain TMF_DNA_bd PF12329.8 EGF76815.1 - 0.0059 16.6 7.6 1.1 9.3 0.0 2.5 1 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF2353 PF09789.9 EGF76815.1 - 0.02 14.3 4.2 0.028 13.8 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 EGF76815.1 - 0.023 13.6 4.5 0.038 12.9 4.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 EGF76815.1 - 0.029 14.8 1.2 0.17 12.3 0.2 2.2 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Golgin_A5 PF09787.9 EGF76815.1 - 0.031 13.8 4.6 0.042 13.3 4.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.12 EGF76815.1 - 0.048 13.7 1.6 7.2 6.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) VPS38 PF17649.1 EGF76815.1 - 0.061 12.2 0.8 0.079 11.8 0.8 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 TMPIT PF07851.13 EGF76815.1 - 0.076 12.2 0.9 0.11 11.8 0.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 EGF76815.1 - 0.11 12.8 5.8 3.4 8.0 2.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BAR_2 PF10455.9 EGF76815.1 - 0.29 10.2 5.9 0.95 8.5 5.9 1.8 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Mod_r PF07200.13 EGF76815.1 - 0.75 9.9 7.7 4.3 7.4 7.7 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein BBP1_C PF15272.6 EGF76815.1 - 0.79 9.5 8.4 2 8.2 8.4 1.8 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF3446 PF11928.8 EGF76815.1 - 1 9.7 10.5 0.37 11.1 7.9 1.5 2 0 0 2 2 1 0 Early growth response N-terminal domain Atg14 PF10186.9 EGF76815.1 - 1.3 8.0 6.1 1.4 7.9 3.7 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31_Bap29_C PF18035.1 EGF76815.1 - 8.5 6.5 9.5 9.4 6.3 4.5 2.3 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cast PF10174.9 EGF76816.1 - 0.00041 18.7 0.4 0.00053 18.4 0.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.9 EGF76816.1 - 0.0019 17.4 1.8 0.0025 16.9 1.8 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin PF00261.20 EGF76816.1 - 0.0028 17.1 4.1 0.044 13.1 0.1 2.0 1 1 1 2 2 2 1 Tropomyosin CENP-F_leu_zip PF10473.9 EGF76816.1 - 0.0035 17.4 3.5 0.0035 17.4 3.5 1.5 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EGF76816.1 - 0.0058 15.6 2.8 0.0081 15.1 2.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.6 EGF76816.1 - 0.0058 16.4 6.1 0.015 15.0 6.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) HAP1_N PF04849.13 EGF76816.1 - 0.0089 15.3 1.4 0.012 14.8 1.4 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region CENP-K PF11802.8 EGF76816.1 - 0.0091 15.6 4.1 0.012 15.2 4.1 1.2 1 0 0 1 1 1 1 Centromere-associated protein K Exonuc_VII_L PF02601.15 EGF76816.1 - 0.0099 15.5 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 EGF76816.1 - 0.01 16.4 3.9 0.019 15.6 2.7 2.1 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0242 PF06785.11 EGF76816.1 - 0.019 15.1 0.8 0.035 14.2 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lzipper-MIP1 PF14389.6 EGF76816.1 - 0.029 14.7 0.3 7.3 7.0 0.0 2.8 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 EGF76816.1 - 0.033 13.9 1.3 0.033 13.9 1.3 2.0 2 1 0 2 2 2 0 Septum formation initiator ADIP PF11559.8 EGF76816.1 - 0.035 14.2 5.5 0.068 13.3 5.5 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding YkyA PF10368.9 EGF76816.1 - 0.035 13.8 1.8 0.051 13.2 1.8 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Filament PF00038.21 EGF76816.1 - 0.037 13.6 1.5 0.055 13.0 1.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein GAS PF13851.6 EGF76816.1 - 0.065 12.6 5.7 0.14 11.5 5.7 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EGF76816.1 - 0.075 13.2 3.3 1.2 9.4 0.7 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HBM PF16591.5 EGF76816.1 - 0.079 12.4 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain Fungal_trans_2 PF11951.8 EGF76816.1 - 0.08 11.7 1.3 0.15 10.8 1.2 1.5 1 1 1 2 2 2 0 Fungal specific transcription factor domain TMPIT PF07851.13 EGF76816.1 - 0.086 12.1 3.5 0.089 12.0 2.7 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EGF76816.1 - 0.1 12.6 0.8 0.23 11.5 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EGF76816.1 - 0.12 13.0 0.6 4.3 8.0 0.1 2.5 1 1 1 2 2 2 0 SlyX TPR_MLP1_2 PF07926.12 EGF76816.1 - 0.12 12.4 4.5 0.24 11.5 1.0 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.12 EGF76816.1 - 0.23 11.8 2.6 1 9.7 1.8 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF724 PF05266.14 EGF76816.1 - 0.25 11.1 3.8 0.39 10.5 3.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 EGF76816.1 - 0.36 11.1 2.5 1.4 9.3 0.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 EGF76816.1 - 0.4 11.2 3.0 0.65 10.5 3.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EGF76816.1 - 0.53 10.5 3.9 2.3 8.5 0.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HMMR_C PF15908.5 EGF76816.1 - 0.68 10.2 8.8 4.5 7.5 0.8 3.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal KxDL PF10241.9 EGF76816.1 - 0.73 10.1 4.0 2.2 8.6 0.7 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein FliD_N PF02465.18 EGF76816.1 - 1.3 9.8 8.4 0.98 10.2 0.7 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BST2 PF16716.5 EGF76816.1 - 1.3 9.6 4.2 1.4 9.5 0.9 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF4200 PF13863.6 EGF76816.1 - 2.1 8.8 6.5 8.9 6.7 6.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) JAKMIP_CC3 PF16034.5 EGF76816.1 - 8.6 6.3 8.0 0.13 12.2 0.6 1.7 2 1 0 2 2 1 0 JAKMIP CC3 domain Ribosomal_S11 PF00411.19 EGF76818.1 - 1.5e-24 86.5 0.2 1.7e-24 86.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DUF1242 PF06842.12 EGF76819.1 - 4.4e-19 68.0 2.1 6.4e-19 67.5 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) SF3b10 PF07189.11 EGF76821.1 - 0.038 14.1 0.7 0.062 13.4 0.0 1.6 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) DUF600 PF04634.12 EGF76821.1 - 0.058 13.4 3.1 0.072 13.1 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF600 DUF1676 PF07898.13 EGF76821.1 - 0.069 13.2 0.5 0.13 12.2 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Toxin_YhaV PF11663.8 EGF76821.1 - 0.084 12.9 2.2 0.14 12.2 2.2 1.4 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Asp PF00026.23 EGF76822.1 - 4.7e-14 52.5 0.1 7.9e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF76822.1 - 0.00027 20.7 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Baculo_p33 PF05214.12 EGF76822.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Baculovirus P33 Golgin_A5 PF09787.9 EGF76823.1 - 0.0097 15.4 2.0 0.012 15.1 2.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Peptidase_M36 PF02128.15 EGF76824.1 - 3.6e-79 266.6 0.4 3.9e-79 266.5 0.4 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 EGF76824.1 - 0.14 11.8 0.4 0.14 11.8 0.4 1.6 1 1 0 1 1 1 0 Peptidase M50B-like MR_MLE_N PF02746.16 EGF76824.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ribonuclease_3 PF00636.26 EGF76825.1 - 9.4e-19 68.0 0.0 2.4e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF76825.1 - 1.1e-10 41.7 0.0 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Sporozoite_P67 PF05642.11 EGF76826.1 - 0.0063 14.7 7.3 0.04 12.0 0.2 2.1 2 0 0 2 2 2 2 Sporozoite P67 surface antigen DUF4600 PF15372.6 EGF76826.1 - 0.0092 16.4 2.4 0.12 12.8 2.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4600) S-antigen PF05756.11 EGF76826.1 - 0.15 12.4 1.2 0.36 11.2 1.2 1.7 1 0 0 1 1 1 0 S-antigen protein Presenilin PF01080.17 EGF76826.1 - 0.15 10.8 5.2 0.054 12.3 2.1 1.7 2 0 0 2 2 2 0 Presenilin Syja_N PF02383.18 EGF76828.1 - 6.7e-53 180.1 0.2 9.5e-53 179.6 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain Chitin_synth_1 PF01644.17 EGF76829.1 - 1.3e-71 239.8 0.0 2e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGF76829.1 - 4.7e-27 93.8 0.0 1.7e-26 92.0 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGF76829.1 - 1.2e-21 77.0 0.0 3.1e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGF76829.1 - 1.2e-06 28.6 0.6 2.8e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 ETF_QO PF05187.13 EGF76830.1 - 8.7e-46 154.4 0.0 1.4e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 EGF76830.1 - 1.7e-07 30.7 1.2 0.0015 17.7 2.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGF76830.1 - 5.4e-07 29.5 0.3 0.00023 20.8 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGF76830.1 - 2.6e-06 27.6 0.1 1.1e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGF76830.1 - 0.0001 21.6 0.1 0.00095 18.5 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EGF76830.1 - 0.00018 21.5 0.4 0.00095 19.2 0.4 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGF76830.1 - 0.00022 20.5 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGF76830.1 - 0.0005 18.9 1.0 0.00075 18.3 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGF76830.1 - 0.0011 18.4 0.3 0.0016 17.7 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGF76830.1 - 0.0014 17.9 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 EGF76830.1 - 0.0019 18.7 0.8 0.0046 17.5 0.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.7 EGF76830.1 - 0.011 15.2 0.2 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGF76830.1 - 0.063 12.3 0.6 0.093 11.8 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EGF76830.1 - 0.083 13.5 0.2 12 6.5 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGF76830.1 - 0.085 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_10 PF13237.6 EGF76830.1 - 0.18 11.9 1.6 0.58 10.3 1.7 1.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain LOH1CR12 PF10158.9 EGF76831.1 - 0.0022 18.0 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Tumour suppressor protein RhoGAP PF00620.27 EGF76832.1 - 8.9e-12 45.1 0.0 2.7e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGF76832.1 - 3e-09 37.0 0.1 3.5e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 EGF76832.1 - 0.00069 19.6 0.0 0.0021 18.1 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4168 PF13767.6 EGF76832.1 - 3.9 8.7 5.4 38 5.5 1.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4168) HgmA PF04209.13 EGF76833.1 - 1.9e-210 699.0 0.0 2.2e-210 698.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase SNARE PF05739.19 EGF76834.1 - 1.4e-05 25.0 1.7 1.4e-05 25.0 1.7 1.8 2 0 0 2 2 1 1 SNARE domain Sec20 PF03908.13 EGF76834.1 - 3.9e-05 23.5 3.7 0.00046 20.1 1.9 2.3 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.15 EGF76834.1 - 0.00043 20.6 2.5 0.0052 17.1 0.1 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGF76834.1 - 0.0015 18.8 3.8 0.0015 18.8 3.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.18 EGF76834.1 - 0.0051 15.1 0.6 0.0074 14.6 0.6 1.2 1 0 0 1 1 1 1 Fusion glycoprotein F0 Otopetrin PF03189.13 EGF76834.1 - 0.018 13.9 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Otopetrin Hum_adeno_E3A PF05393.11 EGF76834.1 - 0.047 13.7 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Imm17 PF15562.6 EGF76834.1 - 0.055 13.3 2.7 0.099 12.5 2.7 1.4 1 0 0 1 1 1 0 Immunity protein 17 Synaptobrevin PF00957.21 EGF76834.1 - 0.096 12.5 7.5 0.036 13.8 4.3 1.9 2 0 0 2 2 2 0 Synaptobrevin Rx_N PF18052.1 EGF76834.1 - 0.14 12.5 1.5 1 9.7 0.1 2.5 2 1 1 3 3 3 0 Rx N-terminal domain SpecificRecomb PF10136.9 EGF76834.1 - 0.28 9.4 3.4 0.11 10.8 0.9 1.5 2 0 0 2 2 2 0 Site-specific recombinase Prominin PF05478.11 EGF76834.1 - 0.35 8.8 6.1 0.17 9.8 3.7 1.6 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 EGF76834.1 - 1.2 9.2 9.0 4.7 7.3 6.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 EGF76834.1 - 6.4 7.0 7.9 1.2 9.4 3.9 1.8 2 1 0 2 2 2 0 Zinc finger-containing protein HisKA_3 PF07730.13 EGF76834.1 - 8.1 7.0 8.1 3.2 8.3 0.7 3.2 2 2 2 4 4 4 0 Histidine kinase CS PF04969.16 EGF76835.1 - 4e-13 50.2 0.0 1.6e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 CS domain GARS_A PF01071.19 EGF76836.1 - 5.9e-80 267.6 0.0 9.7e-80 266.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGF76836.1 - 2.3e-37 128.5 0.0 6.2e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EGF76836.1 - 2.1e-36 124.6 0.2 8.1e-36 122.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EGF76836.1 - 7.3e-29 99.9 0.1 1.7e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGF76836.1 - 1.9e-13 50.9 1.6 5e-13 49.5 0.6 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 EGF76836.1 - 0.0023 18.0 0.0 0.0083 16.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CBP4 PF07960.11 EGF76837.1 - 0.0088 15.9 0.0 0.0097 15.8 0.0 1.1 1 0 0 1 1 1 1 CBP4 Diphthami_syn_2 PF01902.17 EGF76838.1 - 5.6e-43 147.0 0.1 1.7e-42 145.4 0.1 1.6 1 1 0 1 1 1 1 Diphthamide synthase WD40 PF00400.32 EGF76839.1 - 1.1e-39 133.6 18.8 2.2e-06 28.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76839.1 - 4.6e-16 58.9 0.0 0.017 15.4 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF76839.1 - 0.00015 21.2 0.0 0.0011 18.4 0.0 2.7 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 EGF76839.1 - 0.00018 21.5 0.0 0.29 11.0 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGF76839.1 - 0.027 13.1 0.6 1.7 7.2 0.1 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGF76839.1 - 0.093 12.3 0.0 9.6 5.7 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Ge1_WD40 PF16529.5 EGF76839.1 - 0.1 11.6 0.7 37 3.1 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 EGF76840.1 - 9.1e-80 267.8 0.0 1.2e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76840.1 - 1.4e-36 126.1 0.0 1.8e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF76840.1 - 4.7e-06 26.1 0.0 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF76840.1 - 1.1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF76840.1 - 8.9e-05 21.4 0.7 0.00066 18.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGF76840.1 - 0.0057 16.3 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGF76840.1 - 0.0065 16.1 0.0 0.04 13.6 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGF76840.1 - 0.095 12.6 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ECM1 PF05782.11 EGF76840.1 - 0.98 8.3 8.5 1.3 7.9 8.5 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Abhydrolase_1 PF00561.20 EGF76841.1 - 2.2e-05 24.2 0.2 0.0001 22.1 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF76841.1 - 9.8e-05 21.7 0.0 0.0023 17.3 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGF76841.1 - 0.00011 22.0 0.1 0.00026 20.7 0.1 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGF76841.1 - 0.00012 22.8 0.5 0.0058 17.3 0.2 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EGF76841.1 - 0.0032 17.1 0.1 0.0071 16.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase PhoPQ_related PF10142.9 EGF76841.1 - 0.0039 15.9 0.0 0.0056 15.4 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein LIP PF03583.14 EGF76841.1 - 0.0048 16.3 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EGF76841.1 - 0.0056 16.2 0.1 0.035 13.6 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Cutinase PF01083.22 EGF76841.1 - 0.18 11.8 2.6 0.82 9.6 1.2 2.2 2 1 0 2 2 2 0 Cutinase WD40 PF00400.32 EGF76842.1 - 4.1e-20 71.7 20.9 0.00084 20.1 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76842.1 - 0.0053 17.0 1.0 0.34 11.2 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Chalcone_N PF18232.1 EGF76842.1 - 0.036 14.5 0.5 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Chalcone isomerase N-terminal domain Nup160 PF11715.8 EGF76842.1 - 0.074 11.7 2.4 1.9 7.0 0.1 3.3 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Tim17 PF02466.19 EGF76843.1 - 1.4e-26 93.1 4.9 1.6e-26 92.9 4.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 EGF76843.1 - 0.0055 15.9 0.3 0.007 15.5 0.3 1.1 1 0 0 1 1 1 1 Gammaproteobacterial serine protease DUF2156 PF09924.9 EGF76843.1 - 0.044 12.8 0.1 0.05 12.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DUF155 PF02582.14 EGF76844.1 - 4.6e-54 183.2 0.3 6.9e-54 182.6 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AOC_like PF18678.1 EGF76844.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain FIT1_2 PF17357.2 EGF76844.1 - 0.23 11.6 2.6 0.56 10.3 2.6 1.6 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 CAF1C_H4-bd PF12265.8 EGF76845.1 - 8.9e-29 99.6 0.6 2.1e-28 98.4 0.2 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGF76845.1 - 3e-22 78.5 9.3 2.6e-05 24.9 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76845.1 - 5e-06 26.7 0.4 0.0018 18.6 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF76845.1 - 0.0027 17.6 0.3 0.016 15.1 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF2431 PF10354.9 EGF76846.1 - 3.5e-52 177.1 0.0 4.1e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltr_RsmB-F PF01189.17 EGF76846.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PPR PF01535.20 EGF76847.1 - 1.4e-06 28.1 0.5 4.5 7.7 0.0 6.1 8 0 0 8 8 8 2 PPR repeat PPR_2 PF13041.6 EGF76847.1 - 1.5e-05 25.1 1.5 0.63 10.3 0.0 5.5 5 1 1 6 6 6 3 PPR repeat family DnaJ PF00226.31 EGF76848.1 - 8.6e-14 51.4 0.5 1.2e-13 51.0 0.5 1.2 1 0 0 1 1 1 1 DnaJ domain SIT PF15330.6 EGF76848.1 - 0.034 14.6 0.1 0.05 14.1 0.1 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT STIL_N PF15253.6 EGF76849.1 - 5.9e-20 71.6 1.1 8.9e-18 64.4 1.1 2.7 1 1 0 1 1 1 1 SCL-interrupting locus protein N-terminus Abhydrolase_3 PF07859.13 EGF76850.1 - 4.5e-37 128.0 0.0 6e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGF76850.1 - 1.2e-12 47.4 0.0 1.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGF76850.1 - 0.11 11.3 0.0 0.43 9.4 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family DUF4515 PF14988.6 EGF76851.1 - 2.4e-06 27.5 34.5 2.4e-06 27.5 34.5 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4515) DUF4618 PF15397.6 EGF76851.1 - 0.00051 19.5 36.0 0.00092 18.7 36.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) ATP-synt_E PF05680.12 EGF76852.1 - 1.3e-11 44.6 0.2 2e-11 44.1 0.1 1.3 1 1 0 1 1 1 1 ATP synthase E chain CNOT1_HEAT_N PF16419.5 EGF76853.1 - 0.0035 17.1 0.1 0.0053 16.5 0.1 1.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat WD40 PF00400.32 EGF76854.1 - 4.1e-70 230.0 24.4 1.1e-11 45.1 0.3 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76854.1 - 3.5e-29 100.9 3.4 4.9e-05 23.5 0.0 6.1 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF76854.1 - 5e-09 35.3 4.7 0.032 12.9 0.1 5.2 2 2 4 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EGF76854.1 - 2.2e-07 30.9 0.1 0.29 11.0 0.0 3.9 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGF76854.1 - 2.4e-07 30.0 0.0 0.053 12.5 0.0 3.6 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGF76854.1 - 1.3e-05 24.7 2.8 0.073 12.4 0.0 4.3 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal FAD_binding_9 PF08021.11 EGF76854.1 - 0.00018 21.7 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 EGF76854.1 - 0.00024 20.6 0.0 0.77 9.0 0.0 3.9 3 2 2 5 5 5 1 WD40-like domain Cytochrom_D1 PF02239.16 EGF76854.1 - 0.00053 18.6 0.1 0.13 10.8 0.1 3.4 3 1 1 4 4 4 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EGF76854.1 - 0.0025 16.6 1.2 0.82 8.3 0.1 3.2 2 2 1 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 EGF76854.1 - 0.0068 14.8 0.0 2.6 6.3 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ret2_MD PF18528.1 EGF76854.1 - 0.0091 16.3 0.0 12 6.4 0.0 3.1 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain TRAP-delta PF05404.12 EGF76854.1 - 0.072 12.6 0.0 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Coatomer_WDAD PF04053.14 EGF76854.1 - 0.086 11.9 0.0 1.3 8.0 0.0 2.6 2 2 0 3 3 3 0 Coatomer WD associated region Proteasome_A_N PF10584.9 EGF76854.1 - 0.11 12.2 7.0 2.1 8.1 0.1 3.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature IKI3 PF04762.12 EGF76854.1 - 0.12 10.4 1.1 3 5.7 1.1 2.6 1 1 0 1 1 1 0 IKI3 family DUF5122 PF17164.4 EGF76854.1 - 0.94 9.8 3.2 28 5.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller PD40 PF07676.12 EGF76854.1 - 1.4 9.0 8.4 7 6.7 0.1 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Telomere_reg-2 PF10193.9 EGF76855.1 - 7e-16 58.6 0.2 4.4e-15 56.0 0.0 2.4 2 0 0 2 2 2 1 Telomere length regulation protein Proteasome PF00227.26 EGF76856.1 - 2.3e-48 164.2 0.4 2.8e-48 164.0 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-RRN7 PF11781.8 EGF76857.1 - 8.9e-05 22.1 1.1 0.00019 21.0 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 LSM PF01423.22 EGF76858.1 - 4.6e-20 71.1 0.0 5e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF76858.1 - 2.4e-05 24.4 0.0 2.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGF76858.1 - 0.016 15.3 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain Autophagy_N PF03986.13 EGF76860.1 - 8.4e-43 145.6 0.1 1.5e-42 144.8 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGF76860.1 - 1.6e-19 70.2 1.3 3.1e-19 69.3 1.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGF76860.1 - 8.4e-12 44.4 0.8 2.1e-11 43.1 0.8 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CDC50 PF03381.15 EGF76862.1 - 1.5e-88 297.0 0.2 1.8e-88 296.7 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pkinase PF00069.25 EGF76864.1 - 4.1e-52 177.2 4.7 5.4e-52 176.8 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76864.1 - 2.3e-32 112.3 0.0 5.7e-30 104.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF76864.1 - 3e-06 26.8 0.0 9.3e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF76864.1 - 0.0084 14.9 1.9 0.31 9.8 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EGF76864.1 - 0.01 15.8 0.0 2.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PUF PF00806.19 EGF76865.1 - 6.8e-44 145.1 12.5 9.1e-08 31.4 0.2 7.9 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 EGF76865.1 - 5.8e-05 23.5 1.1 0.29 11.5 0.2 3.9 2 2 1 3 3 3 2 CPL (NUC119) domain IQ PF00612.27 EGF76865.1 - 0.017 14.8 0.1 0.04 13.7 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif CCDC92 PF14916.6 EGF76865.1 - 0.3 10.9 3.5 12 5.7 2.5 3.0 2 1 0 2 2 2 0 Coiled-coil domain of unknown function CTP_transf_1 PF01148.20 EGF76866.1 - 2.2e-80 270.2 22.5 2.8e-80 269.9 22.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF1240 PF06836.12 EGF76866.1 - 1.2 9.7 12.2 0.33 11.5 1.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1240) PhoLip_ATPase_C PF16212.5 EGF76868.1 - 7.4e-74 248.6 34.6 7.4e-74 248.6 34.6 2.6 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGF76868.1 - 2.1e-21 75.4 3.6 2.8e-20 71.7 1.4 2.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGF76868.1 - 9.1e-14 51.3 0.0 3.1e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGF76868.1 - 1.6e-10 41.6 0.2 1.9e-05 25.0 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGF76868.1 - 4e-10 39.5 2.0 1.8e-09 37.4 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGF76868.1 - 0.0005 19.9 0.1 0.002 17.9 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YafO_toxin PF13957.6 EGF76868.1 - 0.022 14.8 0.9 0.34 11.0 0.0 2.4 2 0 0 2 2 2 0 Toxin YafO, type II toxin-antitoxin system tRNA-synt_1e PF01406.19 EGF76869.1 - 8.4e-126 419.4 0.5 8.4e-126 419.4 0.5 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGF76869.1 - 2.8e-06 26.3 0.1 9.6e-05 21.3 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGF76869.1 - 0.0016 16.8 0.0 0.0041 15.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 EGF76869.1 - 0.01 16.3 0.0 0.04 14.4 0.0 2.0 1 0 0 1 1 1 0 DALR domain tRNA-synt_1c PF00749.21 EGF76869.1 - 0.029 13.3 1.3 0.6 9.0 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 EGF76869.1 - 0.057 12.3 0.6 0.69 8.8 0.1 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (K) Aminotran_3 PF00202.21 EGF76870.1 - 2.6e-45 154.8 0.1 2.3e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EGF76870.1 - 1.8e-14 54.0 0.0 1.5e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain BATS PF06968.13 EGF76871.1 - 1.7e-19 69.7 0.0 5.2e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGF76871.1 - 2.1e-14 54.2 0.1 3.1e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily AMP-binding PF00501.28 EGF76873.1 - 3.3e-103 345.5 0.0 4.3e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF76873.1 - 3.6e-16 59.9 1.5 6e-16 59.2 0.3 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA_2 PF07724.14 EGF76873.1 - 0.082 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DWNN PF08783.11 EGF76874.1 - 1.5e-31 108.5 0.1 4.8e-31 106.9 0.1 1.9 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 EGF76874.1 - 1.1e-06 28.4 4.9 1.1e-06 28.4 4.9 2.6 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC PF00098.23 EGF76874.1 - 0.0005 20.0 2.2 0.0017 18.4 2.2 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EGF76874.1 - 0.004 17.0 11.9 0.004 17.0 11.9 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF76874.1 - 0.005 16.7 7.3 0.005 16.7 7.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF76874.1 - 0.0063 16.8 9.3 0.0063 16.8 9.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGF76874.1 - 0.016 15.1 8.3 0.016 15.1 8.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF76874.1 - 0.22 11.4 10.9 0.47 10.4 10.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGF76874.1 - 0.26 11.5 11.4 0.56 10.4 11.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGF76874.1 - 0.56 10.3 7.8 1.2 9.2 7.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger MBF1 PF08523.10 EGF76875.1 - 1.3e-18 67.2 1.9 1.3e-18 67.2 1.9 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGF76875.1 - 2.3e-10 40.4 0.0 4.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EGF76875.1 - 0.00013 22.3 0.0 0.00053 20.3 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 EGF76875.1 - 0.05 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RRM_3 PF08777.11 EGF76877.1 - 3.2e-10 40.0 0.8 1.7e-09 37.7 0.2 2.3 2 0 0 2 2 2 1 RNA binding motif La PF05383.17 EGF76877.1 - 0.00048 20.1 0.4 0.0025 17.9 0.0 2.5 2 1 0 2 2 2 1 La domain RRM_1 PF00076.22 EGF76877.1 - 0.026 14.4 1.2 7 6.6 0.1 2.9 2 2 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WLM PF08325.10 EGF76878.1 - 5.5e-56 189.7 0.7 7.3e-56 189.3 0.7 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EGF76878.1 - 0.00049 20.2 0.1 0.001 19.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 EGF76878.1 - 2.1 7.7 10.8 0.082 12.2 4.5 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF1769 PF08588.10 EGF76879.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Beta-Casp PF10996.8 EGF76880.1 - 7.5e-25 87.4 0.0 1.4e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EGF76880.1 - 1.6e-18 66.8 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EGF76880.1 - 1.1e-16 60.5 0.0 2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGF76880.1 - 5.5e-11 42.8 0.1 1.5e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGF76880.1 - 2.4e-09 37.0 0.4 9.1e-09 35.1 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF76880.1 - 0.00089 19.2 0.0 0.0024 17.8 0.0 1.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Spt4 PF06093.13 EGF76881.1 - 6.4e-29 99.9 0.4 7.7e-29 99.6 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TPR_1 PF00515.28 EGF76882.1 - 3.4e-08 33.0 1.2 0.0045 16.8 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76882.1 - 2.3e-06 27.3 0.2 0.01 15.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF76882.1 - 0.0021 17.7 0.1 0.011 15.4 0.1 2.3 3 0 0 3 3 3 1 TPR repeat RET_CLD1 PF17756.1 EGF76882.1 - 0.0034 17.6 0.8 0.0089 16.3 0.8 1.7 1 0 0 1 1 1 1 RET Cadherin like domain 1 TPR_12 PF13424.6 EGF76882.1 - 0.0082 16.4 1.0 2 8.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76882.1 - 0.04 13.9 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76882.1 - 0.065 13.5 0.5 1.1 9.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.15 EGF76882.1 - 0.2 11.8 0.2 0.38 10.9 0.2 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Urb2 PF10441.9 EGF76882.1 - 2.1 8.2 6.9 1.7 8.5 4.5 2.0 2 0 0 2 2 2 0 Urb2/Npa2 family NADH-u_ox-rdase PF10785.9 EGF76883.1 - 6.5e-09 36.4 0.1 7.6e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit WD40 PF00400.32 EGF76884.1 - 3.3e-18 65.7 7.8 5.9e-06 26.9 0.3 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EGF76884.1 - 2.3e-08 33.5 8.6 6.6e-08 32.1 8.6 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 EGF76884.1 - 5.1e-08 33.1 0.1 0.0022 18.3 0.1 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 EGF76884.1 - 7.4e-05 23.0 4.5 7.4e-05 23.0 4.5 2.9 2 0 0 2 2 2 1 Ring finger domain Ge1_WD40 PF16529.5 EGF76884.1 - 0.021 13.8 0.4 1.2 8.0 0.0 2.7 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rep_fac-A_C PF08646.10 EGF76884.1 - 0.69 9.6 3.0 1 9.1 1.8 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain zf-ANAPC11 PF12861.7 EGF76884.1 - 1.1 9.3 8.2 6.2 6.9 8.2 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EGF76884.1 - 6.9 6.9 12.3 7.7 6.8 7.2 3.1 1 1 3 4 4 4 0 FANCL C-terminal domain TPR_2 PF07719.17 EGF76885.1 - 0.0037 17.3 0.3 6.3 7.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76885.1 - 0.023 14.9 2.5 0.11 12.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF76885.1 - 0.069 13.7 3.2 1.9 9.0 0.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF76885.1 - 0.16 11.8 0.2 33 4.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 EGF76886.1 - 1.6e-13 50.3 8.7 2.7e-13 49.6 8.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGF76886.1 - 1.5e-11 44.0 7.4 2.4e-11 43.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF76886.1 - 2.4e-05 24.5 10.0 4.8e-05 23.6 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGF76886.1 - 0.0008 19.3 9.0 0.0019 18.1 9.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGF76886.1 - 0.017 15.0 8.7 0.033 14.0 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GluR_Homer-bdg PF10606.9 EGF76886.1 - 0.076 13.2 0.3 0.076 13.2 0.3 2.0 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor zf-RING_4 PF14570.6 EGF76886.1 - 0.11 12.3 3.7 0.2 11.5 3.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RecR PF02132.15 EGF76886.1 - 0.58 9.8 10.7 0.15 11.7 5.7 2.4 2 0 0 2 2 2 0 RecR protein zf-RING_UBOX PF13445.6 EGF76886.1 - 3.3 7.8 10.7 5.9 7.0 5.5 2.7 2 0 0 2 2 2 0 RING-type zinc-finger UQ_con PF00179.26 EGF76887.1 - 4.1e-46 156.1 0.0 4.6e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGF76887.1 - 2e-05 24.3 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGF76887.1 - 0.17 12.2 0.6 0.3 11.4 0.5 1.5 1 1 0 1 1 1 0 RWD domain ECH_1 PF00378.20 EGF76888.1 - 4.1e-59 199.9 0.0 4.7e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF76888.1 - 6.5e-30 104.8 0.0 6.4e-28 98.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AA_kinase PF00696.28 EGF76889.1 - 1.6e-37 129.4 1.5 2.5e-37 128.8 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EGF76889.1 - 9.9e-17 60.7 0.8 3.6e-16 58.9 0.8 2.0 1 0 0 1 1 1 1 PUA domain zf-MYND PF01753.18 EGF76890.1 - 0.00016 21.7 25.1 0.00055 20.0 25.1 1.9 1 1 0 1 1 1 1 MYND finger Mito_carr PF00153.27 EGF76891.1 - 2.5e-13 49.7 0.0 0.024 14.5 0.0 4.5 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF4719 PF15843.5 EGF76891.1 - 0.09 12.9 2.0 9.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) SYS1 PF09801.9 EGF76892.1 - 4.4e-42 143.6 5.7 5.1e-42 143.4 5.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF4229 PF14012.6 EGF76892.1 - 0.46 10.6 10.2 2.4 8.3 2.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) PI3Ka PF00613.20 EGF76893.1 - 6.9e-60 201.6 1.5 1.1e-59 200.9 1.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGF76893.1 - 2.6e-49 168.3 0.4 5.9e-32 111.4 0.1 2.5 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGF76893.1 - 4.8e-35 120.5 0.0 9.1e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 EGF76893.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Ubiq_cyt_C_chap PF03981.12 EGF76894.1 - 1.9e-32 112.3 0.0 3e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone SIKE PF05769.11 EGF76895.1 - 3.3e-15 56.5 15.8 4.3e-15 56.1 15.8 1.1 1 0 0 1 1 1 1 SIKE family FAM184 PF15665.5 EGF76895.1 - 0.0048 16.7 12.7 0.0065 16.3 12.7 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Prominin PF05478.11 EGF76895.1 - 0.02 12.9 7.5 0.025 12.6 7.5 1.1 1 0 0 1 1 1 0 Prominin KxDL PF10241.9 EGF76895.1 - 0.05 13.9 2.9 0.05 13.9 2.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein ZapB PF06005.12 EGF76895.1 - 0.6 10.6 21.5 1.5 9.3 11.6 2.9 2 1 1 3 3 3 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 EGF76895.1 - 0.88 9.1 9.0 1.1 8.7 9.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PikAIV_N PF18605.1 EGF76895.1 - 3 7.5 13.2 0.85 9.3 3.2 3.4 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain YabA PF06156.13 EGF76895.1 - 4.8 7.9 16.4 5.6 7.7 4.0 3.1 1 1 2 3 3 3 0 Initiation control protein YabA TSNAXIP1_N PF15739.5 EGF76895.1 - 5.5 7.4 13.3 0.61 10.5 5.8 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DBR1 PF05011.13 EGF76896.1 - 1e-20 74.6 0.1 1.6e-20 74.0 0.1 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGF76896.1 - 7.2e-09 36.4 1.4 1.1e-08 35.9 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EGF76896.1 - 0.00031 20.2 0.0 0.00069 19.0 0.0 1.5 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Metallophos_2 PF12850.7 EGF76896.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Dickkopf_N PF04706.12 EGF76897.1 - 0.31 11.6 6.6 0.69 10.4 6.6 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Rap_GAP PF02145.15 EGF76898.1 - 8.3e-16 58.1 0.0 4.1e-08 33.0 0.0 3.0 3 0 0 3 3 3 2 Rap/ran-GAP IF4E PF01652.18 EGF76899.1 - 7.3e-53 178.6 0.1 8.7e-53 178.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RabGAP-TBC PF00566.18 EGF76900.1 - 3.2e-29 102.2 3.4 2.1e-13 50.4 0.0 4.2 3 1 0 3 3 3 3 Rab-GTPase-TBC domain Peptidase_M85 PF13678.6 EGF76901.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease CAF1A PF12253.8 EGF76902.1 - 1.4e-23 82.9 7.3 1.4e-23 82.9 7.3 3.1 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.11 EGF76902.1 - 0.69 8.3 26.5 1.1 7.6 26.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 EGF76902.1 - 2.6 7.3 10.9 5.8 6.2 10.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EGF76902.1 - 8.6 5.0 13.9 20 3.8 13.9 1.5 1 0 0 1 1 1 0 Presenilin Exo_endo_phos PF03372.23 EGF76903.1 - 0.0072 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CCDC14 PF15254.6 EGF76903.1 - 0.056 12.1 4.4 0.086 11.5 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 WD40 PF00400.32 EGF76904.1 - 0.015 16.2 0.2 18 6.4 0.1 3.9 2 0 0 2 2 2 0 WD domain, G-beta repeat GRP PF07172.11 EGF76905.1 - 0.00022 21.9 3.3 0.00025 21.7 3.3 1.1 1 0 0 1 1 1 1 Glycine rich protein family Keratin_2_head PF16208.5 EGF76905.1 - 0.022 14.9 9.0 0.027 14.6 9.0 1.2 1 0 0 1 1 1 0 Keratin type II head AMP-binding PF00501.28 EGF76906.1 - 8.6e-81 271.7 0.0 1.2e-80 271.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 EGF76907.1 - 2.4e-68 224.4 35.9 4.4e-08 33.7 0.2 12.4 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 EGF76907.1 - 5.1e-43 146.4 2.4 1.1e-42 145.4 2.4 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGF76907.1 - 3.5e-20 72.1 7.5 0.014 15.7 0.0 9.1 2 2 8 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGF76907.1 - 3.2e-11 42.6 11.0 0.00061 18.6 0.2 5.5 3 2 1 4 4 4 3 Nup133 N terminal like WD40_like PF17005.5 EGF76907.1 - 8.3e-07 28.6 12.3 0.0037 16.6 3.0 4.4 3 2 3 6 6 6 3 WD40-like domain NUP214 PF16755.5 EGF76907.1 - 1.2e-05 24.7 4.8 1.4e-05 24.5 0.4 2.5 2 1 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Cytochrom_D1 PF02239.16 EGF76907.1 - 1.8e-05 23.4 0.1 6.2e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 EGF76907.1 - 0.00022 20.0 11.4 1.3 7.6 2.3 5.4 4 3 1 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF76907.1 - 0.0013 17.8 12.7 3.5 6.5 0.2 6.6 2 2 5 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Fusion_gly_K PF01621.17 EGF76907.1 - 0.06 12.4 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Cell fusion glycoprotein K Myosin-VI_CBD PF16521.5 EGF76907.1 - 0.072 13.1 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Myosin VI cargo binding domain Utp12 PF04003.12 EGF76907.1 - 0.12 12.7 0.9 0.27 11.6 0.9 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family BRCT_3 PF18428.1 EGF76909.1 - 7.4e-14 51.7 1.7 2.8e-10 40.2 0.9 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGF76909.1 - 2.2e-12 47.2 0.1 4.2e-09 36.7 0.1 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGF76909.1 - 1e-09 38.6 0.1 0.0016 18.7 0.1 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGF76909.1 - 2.1e-05 24.3 0.1 0.0006 19.6 0.0 2.8 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Rad9_Rad53_bind PF08605.10 EGF76909.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 EGF76909.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain p450 PF00067.22 EGF76910.1 - 6.6e-25 87.8 0.5 1.1e-24 87.1 0.5 1.3 1 1 0 1 1 1 1 Cytochrome P450 Holin_9 PF16936.5 EGF76910.1 - 0.032 14.4 0.6 0.059 13.5 0.6 1.4 1 0 0 1 1 1 0 Putative holin Adap_comp_sub PF00928.21 EGF76913.1 - 8e-85 284.4 0.5 1e-84 284.1 0.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGF76913.1 - 0.00053 19.9 0.3 0.00098 19.1 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TAA-Trp-ring PF15401.6 EGF76913.1 - 0.15 12.6 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin ADK PF00406.22 EGF76914.1 - 7.4e-57 191.7 0.0 8.8e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGF76914.1 - 9.9e-19 68.1 0.0 1.4e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGF76914.1 - 3.5e-17 62.1 0.0 1.7e-16 59.9 0.0 2.2 3 0 0 3 3 3 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGF76914.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain 2OG-FeII_Oxy_2 PF13532.6 EGF76915.1 - 1e-33 117.2 0.5 2e-33 116.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 EGF76916.1 - 9.8e-19 67.4 9.9 1.9e-05 25.3 0.4 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76916.1 - 0.00096 19.4 0.1 0.1 12.9 0.0 3.3 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SoxE PF06525.11 EGF76918.1 - 0.0046 16.4 0.3 0.0067 15.9 0.3 1.2 1 0 0 1 1 1 1 Sulfocyanin (SoxE) domain Copper-bind PF00127.20 EGF76918.1 - 0.0092 16.4 0.1 0.013 16.0 0.1 1.2 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family FAP PF07174.11 EGF76918.1 - 9.7 5.5 30.5 11 5.3 30.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Forkhead_N PF08430.12 EGF76919.1 - 4.2 8.0 30.1 1 10.0 25.3 2.1 2 0 0 2 2 2 0 Forkhead N-terminal region Keratin_2_head PF16208.5 EGF76919.1 - 4.3 7.5 38.6 1.2e+02 2.7 38.6 2.2 1 1 0 1 1 1 0 Keratin type II head CENP-H PF05837.12 EGF76920.1 - 0.00038 20.9 9.5 0.00038 20.9 9.5 1.6 2 0 0 2 2 2 1 Centromere protein H (CENP-H) TMPIT PF07851.13 EGF76920.1 - 0.005 16.1 7.0 0.0089 15.3 7.0 1.3 1 0 0 1 1 1 1 TMPIT-like protein COG2 PF06148.11 EGF76920.1 - 0.0066 16.5 0.6 0.0066 16.5 0.6 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Ku_PK_bind PF08785.11 EGF76920.1 - 0.0082 16.3 0.4 0.016 15.3 0.4 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Colicin PF01024.19 EGF76920.1 - 0.025 14.5 0.8 0.037 13.9 0.8 1.3 1 0 0 1 1 1 0 Colicin pore forming domain EutB PF06751.11 EGF76920.1 - 0.028 13.3 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) FapA PF03961.13 EGF76920.1 - 0.092 11.3 5.0 0.12 11.0 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Neur_chan_memb PF02932.16 EGF76920.1 - 2.5 8.1 7.5 0.39 10.7 1.8 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Halogen_Hydrol PF10112.9 EGF76920.1 - 5.2 7.1 9.5 7.5 6.5 0.4 2.2 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Dynactin_p22 PF07426.11 EGF76921.1 - 0.15 11.9 2.5 0.62 9.9 0.1 2.5 2 1 1 3 3 3 0 Dynactin subunit p22 Pkinase PF00069.25 EGF76922.1 - 5.5e-12 45.6 0.0 2e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF76922.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family HSDR_N PF04313.14 EGF76922.1 - 0.00061 19.8 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.22 EGF76922.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EGF76922.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF76922.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF76922.1 - 0.018 13.8 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGF76922.1 - 0.018 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_Tyr PF07714.17 EGF76922.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF76922.1 - 0.034 13.7 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF76922.1 - 0.16 11.9 0.5 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DnaJ-X PF14308.6 EGF76923.1 - 2.8e-36 125.0 0.0 1.1e-35 123.0 0.0 1.9 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF76923.1 - 4.6e-23 81.1 1.0 1e-22 80.0 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain MetOD2 PF18548.1 EGF76924.1 - 0.02 15.0 1.3 0.044 13.9 1.3 1.7 1 0 0 1 1 1 0 Metanogen output domain 2 Erp_C PF06780.11 EGF76924.1 - 0.02 14.9 1.9 0.033 14.2 1.9 1.3 1 0 0 1 1 1 0 Erp protein C-terminus Spc7 PF08317.11 EGF76924.1 - 0.054 12.4 1.7 0.081 11.8 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Scaffolding_pro PF11418.8 EGF76924.1 - 0.075 13.6 0.1 0.92 10.1 0.0 2.2 2 0 0 2 2 2 0 Phi29 scaffolding protein Cast PF10174.9 EGF76925.1 - 0.0025 16.2 2.7 0.0036 15.6 2.7 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.6 EGF76925.1 - 0.0044 16.8 8.9 0.0064 16.3 8.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Phage_HK97_TLTM PF06120.11 EGF76925.1 - 0.0051 16.0 1.4 0.0066 15.7 1.4 1.2 1 0 0 1 1 1 1 Tail length tape measure protein APG17 PF04108.12 EGF76925.1 - 0.0081 15.3 0.2 0.0094 15.1 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 HAP1_N PF04849.13 EGF76925.1 - 0.012 14.8 3.6 0.017 14.4 3.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FAM76 PF16046.5 EGF76925.1 - 0.015 14.6 1.6 0.019 14.3 1.6 1.2 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 EGF76925.1 - 0.029 13.3 4.7 0.039 12.8 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EGF76925.1 - 0.079 13.6 3.4 0.11 13.1 2.7 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LPP PF04728.13 EGF76925.1 - 0.12 12.7 0.7 0.41 11.1 0.4 1.9 1 1 1 2 2 2 0 Lipoprotein leucine-zipper FliD_N PF02465.18 EGF76925.1 - 0.16 12.7 10.5 0.16 12.7 1.6 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4806 PF16064.5 EGF76925.1 - 0.18 12.1 1.0 1.3 9.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) DivIC PF04977.15 EGF76925.1 - 0.23 11.2 0.7 0.5 10.2 0.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF16 PF01519.16 EGF76925.1 - 0.32 11.5 2.7 1.9 9.1 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4315 PF14193.6 EGF76925.1 - 0.39 10.8 3.7 0.87 9.6 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) TMPIT PF07851.13 EGF76925.1 - 0.55 9.4 2.6 0.79 8.9 2.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 EGF76925.1 - 1.2 9.2 10.4 0.93 9.5 5.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.22 EGF76931.1 - 4.2e-19 68.1 0.1 1.4e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KAR9 PF08580.10 EGF76931.1 - 2.6 6.5 9.0 3.3 6.1 9.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 LRR_4 PF12799.7 EGF76932.1 - 6.1e-09 36.0 3.5 0.0019 18.5 0.0 4.0 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF76932.1 - 0.0097 15.7 2.9 0.044 13.5 0.1 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRRNT PF01462.18 EGF76932.1 - 0.15 11.7 1.0 1.6 8.5 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 EGF76932.1 - 0.2 12.3 4.6 36 5.5 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat DIOX_N PF14226.6 EGF76933.1 - 1.7e-26 93.3 0.0 2.6e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGF76933.1 - 3.2e-20 72.5 0.0 6.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MCM PF00493.23 EGF76934.1 - 1.8e-78 262.7 0.0 2.9e-78 262.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF76934.1 - 1.4e-18 67.0 1.0 1.4e-18 67.0 1.0 1.7 1 1 1 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EGF76934.1 - 1.6e-17 63.6 0.5 3.1e-17 62.8 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGF76934.1 - 6.2e-08 32.3 0.0 0.00076 18.9 0.0 3.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGF76934.1 - 1.1e-07 31.9 0.0 4.6e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGF76934.1 - 0.00072 19.8 0.1 0.25 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGF76934.1 - 0.0012 19.2 0.2 0.076 13.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 EGF76934.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGF76934.1 - 0.0033 17.2 0.0 0.4 10.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGF76934.1 - 0.022 15.1 0.2 3.2 8.2 0.0 3.3 3 1 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 EGF76934.1 - 0.025 14.3 0.0 0.48 10.1 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 EGF76934.1 - 0.078 13.1 0.6 3 8.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 EGF76934.1 - 0.082 13.3 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF76934.1 - 0.13 12.8 0.0 1 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EGF76934.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Pkinase PF00069.25 EGF76935.1 - 3.6e-62 210.1 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF76935.1 - 1.5e-22 80.2 0.0 2.2e-22 79.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF76935.1 - 0.00023 20.6 0.0 0.00058 19.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGF76935.1 - 0.0069 16.3 0.2 0.069 13.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EGF76935.1 - 0.044 14.0 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Choline_kinase PF01633.20 EGF76935.1 - 0.091 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EGF76935.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGF76935.1 - 0.21 10.9 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NMT_C PF02799.15 EGF76936.1 - 4.1e-78 261.7 0.1 8.9e-78 260.6 0.1 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGF76936.1 - 1.6e-76 255.6 0.0 3.8e-76 254.3 0.0 1.7 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EGF76936.1 - 0.0001 22.4 0.0 0.00065 19.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF76936.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF76936.1 - 0.026 14.5 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ALIX_LYPXL_bnd PF13949.6 EGF76936.1 - 0.04 13.2 2.2 0.064 12.5 2.2 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Acetyltransf_7 PF13508.7 EGF76936.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 EGF76937.1 - 3e-09 36.3 0.2 6.9e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Glyco_transf_41 PF13844.6 EGF76939.1 - 1.3e-52 178.8 0.3 6.9e-49 166.6 0.0 2.5 2 1 1 3 3 3 2 Glycosyl transferase family 41 Promethin PF16015.5 EGF76940.1 - 9e-09 35.2 10.7 9e-09 35.2 10.7 1.7 2 0 0 2 2 2 1 Promethin Phage_holin_3_6 PF07332.11 EGF76940.1 - 0.013 15.5 6.6 0.029 14.4 6.6 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2749 PF10907.8 EGF76940.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) RCC1 PF00415.18 EGF76941.1 - 4.2e-75 248.2 10.4 3.2e-12 46.9 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF76941.1 - 6.6e-32 108.6 32.9 2.1e-05 24.2 0.2 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EGF76941.1 - 0.038 13.7 0.0 11 5.7 0.0 3.2 3 0 0 3 3 3 0 TUP1-like enhancer of split SUZ PF12752.7 EGF76942.1 - 1.3e-08 35.5 1.6 1.8e-08 35.0 0.1 1.9 2 0 0 2 2 2 1 SUZ domain SRP54 PF00448.22 EGF76943.1 - 4.7e-51 173.2 0.1 1e-50 172.1 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EGF76943.1 - 6e-47 161.0 6.2 9.3e-47 160.3 6.2 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EGF76943.1 - 8.3e-09 35.6 0.1 4.1e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EGF76943.1 - 7.1e-06 25.2 0.0 1.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGF76943.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF76943.1 - 0.0041 16.8 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGF76943.1 - 0.008 16.2 0.0 0.071 13.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase CbiA PF01656.23 EGF76943.1 - 0.01 15.9 0.0 0.032 14.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EGF76943.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 EGF76943.1 - 0.02 14.8 0.1 0.85 9.5 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGF76943.1 - 0.047 14.2 2.3 0.5 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 EGF76943.1 - 0.058 12.6 0.2 0.72 9.0 0.0 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_17 PF13207.6 EGF76943.1 - 0.078 13.4 0.0 0.49 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGF76943.1 - 0.11 12.9 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PX PF00787.24 EGF76944.1 - 1.2e-20 73.6 0.1 3.4e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 PX domain PXA PF02194.15 EGF76944.1 - 3.3e-06 27.2 4.4 8.3e-06 25.9 0.3 3.5 3 1 0 3 3 3 1 PXA domain RGS PF00615.19 EGF76944.1 - 6.7e-05 23.1 0.0 0.00031 21.0 0.0 2.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Nexin_C PF08628.12 EGF76944.1 - 0.00012 22.6 0.1 0.00076 20.0 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal CHIP_TPR_N PF18391.1 EGF76944.1 - 0.26 12.1 4.1 1.3 9.9 0.0 3.6 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain SH3_1 PF00018.28 EGF76945.1 - 1.6e-08 34.1 0.1 2.7e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF76945.1 - 6.3e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGF76945.1 - 8.6e-06 25.5 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BssC_TutF PF08201.11 EGF76945.1 - 0.089 12.8 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 BssC/TutF protein RE_NgoPII PF09521.10 EGF76945.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease DUF2244 PF10003.9 EGF76945.1 - 3.3 7.4 12.3 0.17 11.5 5.0 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) BUD22 PF09073.10 EGF76946.1 - 3.4e-44 151.9 41.0 2.1e-36 126.2 24.2 2.1 2 0 0 2 2 2 2 BUD22 Synapsin_N PF10581.9 EGF76946.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Synapsin N-terminal VPS28 PF03997.12 EGF76948.1 - 7.8e-74 247.4 0.6 8.9e-74 247.3 0.6 1.0 1 0 0 1 1 1 1 VPS28 protein RFC1 PF08519.12 EGF76948.1 - 0.086 13.0 0.0 0.69 10.1 0.0 2.1 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain ATP-synt_D PF01813.17 EGF76949.1 - 3.6e-73 245.6 3.3 4.4e-73 245.3 3.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D IDEAL PF08858.10 EGF76949.1 - 5.6 6.8 7.1 14 5.6 2.5 2.5 2 0 0 2 2 2 0 IDEAL domain WD40 PF00400.32 EGF76950.1 - 8.6e-13 48.6 0.0 0.23 12.4 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76950.1 - 4.1e-08 33.4 0.0 0.63 10.4 0.0 5.7 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGF76950.1 - 4.8e-05 23.2 0.0 7.2 6.7 0.1 4.1 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGF76950.1 - 6.8e-05 21.6 0.4 0.0013 17.4 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGF76950.1 - 0.0053 15.8 0.3 1.3 7.9 0.0 3.7 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 EGF76950.1 - 0.014 13.8 0.0 0.076 11.4 0.0 2.1 2 1 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Spermine_synth PF01564.17 EGF76951.1 - 7.3e-69 230.9 0.0 2.6e-68 229.2 0.0 1.9 3 0 0 3 3 3 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGF76951.1 - 1.2e-21 76.3 0.2 2e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGF76951.1 - 6.7e-05 23.5 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.14 EGF76951.1 - 0.0026 17.0 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.12 EGF76951.1 - 0.0027 18.4 0.0 0.0075 17.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGF76951.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EGF76951.1 - 0.04 13.2 0.6 0.17 11.1 0.3 1.9 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EGF76951.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Gly_transf_sug PF04488.15 EGF76952.1 - 1.2e-15 57.9 0.1 2.6e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gly_transf_sug PF04488.15 EGF76953.1 - 2.7e-16 60.0 0.1 5.1e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif EMP70 PF02990.16 EGF76954.1 - 1.5e-208 693.7 10.7 2.2e-208 693.2 10.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Ribosomal_S3Ae PF01015.18 EGF76955.1 - 1.6e-89 298.8 7.4 1.9e-89 298.6 7.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EGF76955.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Zip PF02535.22 EGF76956.1 - 6.9e-29 101.1 7.9 6.9e-29 101.1 7.9 2.1 1 1 1 2 2 2 1 ZIP Zinc transporter Plasmid_stab_B PF10784.9 EGF76956.1 - 0.024 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein Band_3_cyto PF07565.13 EGF76956.1 - 0.76 9.5 3.6 1.2 8.9 3.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Nckap1 PF09735.9 EGF76957.1 - 1.1e-166 556.9 15.0 1.5e-166 556.4 15.0 1.2 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Mnd1 PF03962.15 EGF76958.1 - 6.9e-28 96.7 0.1 1.2e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGF76958.1 - 0.0016 18.5 0.6 0.0051 16.9 0.2 2.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain CagE_TrbE_VirB PF03135.14 EGF76958.1 - 0.046 13.8 0.1 0.17 12.0 0.0 1.9 1 1 1 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system Ring_hydroxyl_B PF00866.18 EGF76958.1 - 0.047 13.8 0.2 0.068 13.3 0.2 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Penicillinase_R PF03965.16 EGF76958.1 - 0.052 13.9 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 Penicillinase repressor DUF3361 PF11841.8 EGF76958.1 - 0.053 13.5 0.8 0.07 13.1 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) LXG PF04740.12 EGF76959.1 - 0.00059 19.6 1.3 0.00076 19.2 1.3 1.0 1 0 0 1 1 1 1 LXG domain of WXG superfamily APG17 PF04108.12 EGF76959.1 - 0.007 15.5 1.3 0.0089 15.2 1.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF684 PF05075.14 EGF76959.1 - 0.06 12.3 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF684) DUF2207 PF09972.9 EGF76959.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 EGF76959.1 - 0.2 11.6 1.7 0.81 9.7 0.6 2.3 2 1 0 2 2 2 0 SNARE domain OAD_gamma PF04277.13 EGF76959.1 - 0.83 10.3 3.7 1.8 9.2 3.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SBDS_C PF09377.10 EGF76960.1 - 3.7e-38 130.1 0.9 3.7e-38 130.1 0.9 1.9 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 EGF76960.1 - 5.8e-34 116.0 1.9 1.2e-33 115.1 1.9 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TM_PBP2_N PF16296.5 EGF76960.1 - 0.009 16.1 0.9 4.9 7.4 0.0 3.2 2 1 1 3 3 3 2 N-terminal of TM subunit in PBP-dependent ABC transporters SLS PF14611.6 EGF76960.1 - 0.035 13.9 3.1 0.42 10.4 0.2 2.2 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Dopey_N PF04118.14 EGF76962.1 - 2.7e-99 332.2 0.1 2.7e-99 332.2 0.1 3.1 3 0 0 3 3 3 1 Dopey, N-terminal HEAT_EZ PF13513.6 EGF76962.1 - 0.66 10.5 2.4 2.3 8.8 0.1 3.0 3 0 0 3 3 3 0 HEAT-like repeat Prenyltrans PF00432.21 EGF76963.1 - 1.5e-45 152.6 9.6 1.1e-09 37.8 0.1 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGF76963.1 - 0.00016 20.9 0.1 0.53 9.3 0.0 2.7 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGF76963.1 - 0.00082 18.6 0.2 0.21 10.6 0.0 2.9 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain TPR_1 PF00515.28 EGF76964.1 - 8.8e-27 91.8 10.4 0.0031 17.3 0.1 13.5 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGF76964.1 - 1.4e-26 90.4 14.1 0.031 14.4 0.0 13.9 15 0 0 15 15 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGF76964.1 - 8.2e-23 78.7 6.7 0.17 12.2 0.0 13.5 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGF76964.1 - 9.3e-23 80.5 26.9 0.0014 19.1 0.3 10.2 8 2 1 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGF76964.1 - 9.2e-17 60.5 25.3 0.005 16.5 0.2 11.5 8 4 3 11 11 11 5 TPR repeat TPR_14 PF13428.6 EGF76964.1 - 5.1e-16 58.0 22.3 0.33 11.9 0.0 12.8 10 2 4 14 14 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF76964.1 - 1.3e-14 54.2 16.4 0.19 12.1 0.0 10.2 10 2 3 13 13 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGF76964.1 - 2.6e-11 44.0 13.2 0.059 14.0 0.5 9.2 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGF76964.1 - 6.9e-08 32.6 20.2 0.26 12.0 0.1 11.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF76964.1 - 3.2e-07 30.3 21.4 4.6 7.8 0.2 10.6 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF76964.1 - 6e-07 29.1 6.3 8.1 6.7 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF76964.1 - 0.0087 16.2 4.1 3.1 8.0 0.0 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF2225 PF09986.9 EGF76964.1 - 0.0094 15.7 0.1 0.2 11.3 0.0 2.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF2989 PF11207.8 EGF76964.1 - 0.075 12.8 0.0 0.075 12.8 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF2989) Acetyltransf_13 PF13880.6 EGF76965.1 - 1.9e-24 85.4 0.0 3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EGF76965.1 - 2.6e-15 55.9 2.2 5.2e-15 55.0 2.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EGF76965.1 - 0.0072 16.7 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF76965.1 - 0.021 15.1 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF76965.1 - 0.042 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tfb2 PF03849.14 EGF76966.1 - 3.5e-138 460.4 0.1 4.1e-138 460.2 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGF76966.1 - 2.4e-24 85.5 0.4 4.8e-24 84.6 0.4 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGF76966.1 - 0.00031 20.9 0.0 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IPP-2 PF04979.14 EGF76967.1 - 3.6e-22 79.5 0.9 3.6e-22 79.5 0.9 2.1 3 0 0 3 3 3 1 Protein phosphatase inhibitor 2 (IPP-2) GAGA PF09237.11 EGF76967.1 - 0.072 12.9 0.2 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 GAGA factor GGACT PF06094.12 EGF76968.1 - 8.8e-19 68.3 0.1 1.1e-18 67.9 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Thg1 PF04446.12 EGF76968.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 2 0 0 2 2 2 0 tRNAHis guanylyltransferase Taxilin PF09728.9 EGF76969.1 - 6.2e-48 163.6 35.7 6.2e-48 163.6 35.7 2.1 2 0 0 2 2 2 1 Myosin-like coiled-coil protein Integrin_B_tail PF07965.12 EGF76969.1 - 0.1 13.1 5.7 6.5 7.3 5.7 3.0 1 1 0 1 1 1 0 Integrin beta tail domain Fez1 PF06818.15 EGF76969.1 - 0.72 10.3 33.1 0.096 13.1 24.4 2.9 1 1 1 2 2 2 0 Fez1 WXG100 PF06013.12 EGF76969.1 - 1.8 8.8 10.3 9.6 6.5 0.4 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF4201 PF13870.6 EGF76969.1 - 4.1 7.1 35.8 0.057 13.1 21.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) GIT_CC PF16559.5 EGF76969.1 - 4.2 7.3 14.5 1.3 8.9 1.2 3.7 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 EGF76969.1 - 4.9 7.2 13.3 0.065 13.3 2.9 2.9 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) WD40 PF00400.32 EGF76970.1 - 2.7e-42 142.0 36.2 1.3e-05 25.9 0.8 12.8 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF76970.1 - 0.00028 21.1 7.4 1.2 9.5 0.0 6.6 6 2 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF76970.1 - 0.0011 18.9 0.4 8.4 6.2 0.1 4.1 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGF76970.1 - 0.0078 15.6 0.0 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 EGF76970.1 - 0.021 14.8 0.0 42 4.2 0.0 4.6 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region TFIIIC_delta PF12657.7 EGF76970.1 - 0.033 14.1 2.3 0.23 11.4 0.0 3.2 3 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term CBM_19 PF03427.13 EGF76970.1 - 0.037 14.0 0.2 1.1 9.3 0.2 2.9 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) zf-Tim10_DDP PF02953.15 EGF76971.1 - 4.4e-15 55.1 0.7 4.7e-15 55.0 0.7 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FTHFS PF01268.19 EGF76972.1 - 1.1e-256 852.4 0.2 1.1e-256 852.4 0.2 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EGF76972.1 - 1.4e-66 222.7 4.9 1.4e-66 222.7 4.9 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGF76972.1 - 3.6e-39 133.6 0.1 7.7e-39 132.6 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 EGF76972.1 - 0.48 10.5 4.4 8.4 6.4 1.0 3.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BSD PF03909.17 EGF76973.1 - 3.6e-14 52.5 3.4 4e-14 52.4 1.6 2.1 2 0 0 2 2 2 1 BSD domain Rad60-SLD PF11976.8 EGF76973.1 - 9.5e-08 31.8 0.1 0.0058 16.4 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Proteasome PF00227.26 EGF76974.1 - 7.5e-32 110.3 0.0 9.4e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Nefa_Nip30_N PF10187.9 EGF76975.1 - 3.8e-18 65.8 8.1 6.1e-18 65.1 8.1 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Gaa1 PF04114.14 EGF76976.1 - 2.9e-127 425.7 7.2 3.4e-127 425.5 7.2 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component AlaDh_PNT_N PF05222.15 EGF76978.1 - 4.3e-24 85.3 0.0 6.5e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGF76978.1 - 0.0015 17.9 0.1 0.0036 16.6 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain RasGAP PF00616.19 EGF76980.1 - 9.1e-30 103.9 0.0 8.7e-28 97.5 0.0 3.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGF76980.1 - 2e-26 92.2 0.2 4.1e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain LIM PF00412.22 EGF76980.1 - 1.9e-20 72.8 45.1 5.8e-09 36.1 3.5 4.7 5 0 0 5 5 5 3 LIM domain C1_1 PF00130.22 EGF76980.1 - 0.00038 20.3 8.9 0.00038 20.3 8.9 5.1 3 1 1 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) MTP18 PF10558.9 EGF76981.1 - 1.5e-53 181.3 2.9 5e-27 94.9 0.5 2.0 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Scramblase PF03803.15 EGF76983.1 - 1.3e-45 155.4 0.0 1.6e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Scramblase LOR PF04525.12 EGF76983.1 - 0.0066 16.1 0.1 0.74 9.4 0.1 2.8 1 1 2 3 3 3 1 LURP-one-related HAD PF12710.7 EGF76984.1 - 5.5e-15 56.3 0.1 8.9e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGF76984.1 - 1.8e-07 30.8 0.1 4.8e-05 22.9 0.1 2.1 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 EGF76984.1 - 0.00022 20.8 0.1 0.00044 19.8 0.0 1.4 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF4931 PF16285.5 EGF76984.1 - 0.082 12.2 0.0 0.41 9.9 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4931) Hydrolase PF00702.26 EGF76984.1 - 0.19 12.0 2.4 4.9 7.4 0.1 2.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CENP-C_C PF11699.8 EGF76985.1 - 2.6e-26 91.7 0.0 4.7e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 EGF76985.1 - 2.3e-06 28.3 2.4 2.3e-06 28.3 2.4 4.5 4 1 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EGF76985.1 - 0.0028 17.3 0.0 0.0075 16.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGF76985.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain Guanylate_kin PF00625.21 EGF76986.1 - 6.6e-46 156.3 0.4 1.2e-41 142.4 0.0 2.8 2 1 1 3 3 3 2 Guanylate kinase LRR_4 PF12799.7 EGF76986.1 - 1.2e-25 89.1 21.5 4.1e-05 23.9 2.5 5.9 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF76986.1 - 9.5e-15 54.1 19.8 2.4e-05 24.0 0.8 5.4 2 1 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 EGF76986.1 - 2e-08 34.0 9.8 0.00012 21.6 1.6 3.0 1 1 1 2 2 2 2 Leucine-rich repeat AAA_18 PF13238.6 EGF76986.1 - 3.8e-06 27.5 0.0 0.00016 22.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain LRR_6 PF13516.6 EGF76986.1 - 2.2e-05 24.2 19.6 6.1 7.2 0.0 8.5 9 0 0 9 9 9 2 Leucine Rich repeat AAA_33 PF13671.6 EGF76986.1 - 0.00073 19.7 0.0 0.011 15.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain LRR_1 PF00560.33 EGF76986.1 - 0.00084 19.6 17.1 19 6.3 0.0 8.0 8 0 0 8 8 8 0 Leucine Rich Repeat Rad17 PF03215.15 EGF76986.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EGF76986.1 - 0.064 13.4 1.1 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain BING4CT PF08149.11 EGF76986.1 - 0.11 12.3 0.5 20 5.0 0.0 2.7 3 0 0 3 3 3 0 BING4CT (NUC141) domain Glyco_transf_21 PF13506.6 EGF76987.1 - 6e-39 133.3 0.0 8.9e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGF76987.1 - 2.2e-24 86.6 0.0 3.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF76987.1 - 1.4e-13 51.2 3.4 2.2e-13 50.6 3.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGF76987.1 - 2.6e-07 30.6 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ribosomal_L32e PF01655.18 EGF76989.1 - 3.1e-51 172.3 0.8 3.6e-51 172.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Lipase_GDSL_2 PF13472.6 EGF76990.1 - 7.8e-12 45.9 0.0 1.1e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGF76990.1 - 0.00019 21.5 0.0 0.0012 18.9 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TetR_C_17 PF17922.1 EGF76990.1 - 0.17 12.0 0.3 0.46 10.6 0.2 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YjeF_N PF03853.15 EGF76991.1 - 2.8e-36 125.0 0.0 3.4e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HIT PF01230.23 EGF76992.1 - 1.7e-23 83.2 0.6 2e-23 83.0 0.6 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGF76992.1 - 1.5e-06 28.6 0.4 1.8e-06 28.4 0.4 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGF76992.1 - 0.065 13.1 0.2 0.089 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EGF76992.1 - 0.077 12.7 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF1280 PF06918.14 EGF76992.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DUF202 PF02656.15 EGF76993.1 - 4.5e-16 59.0 2.9 6.1e-16 58.6 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4064 PF13273.6 EGF76993.1 - 0.043 14.1 7.3 0.08 13.2 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4231 PF14015.6 EGF76993.1 - 0.37 11.3 2.9 0.97 9.9 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) PPR_2 PF13041.6 EGF76994.1 - 0.0012 19.0 3.3 2 8.7 0.1 4.3 4 1 1 5 5 5 2 PPR repeat family FERM_N PF09379.10 EGF76994.1 - 0.16 12.0 0.1 0.45 10.5 0.1 1.8 1 0 0 1 1 1 0 FERM N-terminal domain ECH_1 PF00378.20 EGF76995.1 - 4.1e-59 199.9 0.0 4.7e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF76995.1 - 6.5e-30 104.8 0.0 6.4e-28 98.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CTU2 PF10288.9 EGF76996.1 - 3.4e-15 56.3 5.6 1.1e-14 54.6 5.6 2.0 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 EGF76996.1 - 0.00023 21.0 0.0 0.038 13.7 0.0 2.3 1 1 1 2 2 2 2 PP-loop family Pet191_N PF10203.9 EGF76997.1 - 4.4e-14 52.5 1.4 5.6e-07 29.8 0.4 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 AstE_AspA PF04952.14 EGF76998.1 - 5.7e-38 130.6 0.0 8.3e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.11 EGF76998.1 - 2.2e-21 76.7 0.0 1.8e-18 67.1 0.0 2.7 2 1 0 2 2 2 2 HutD Cupin_3 PF05899.12 EGF76998.1 - 0.019 14.7 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) FRB_dom PF08771.11 EGF76999.1 - 0.071 13.5 3.1 1.5 9.3 0.2 2.8 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain ADK PF00406.22 EGF77000.1 - 9.6e-189 619.8 0.0 1e-48 165.3 0.0 4.1 4 0 0 4 4 4 4 Adenylate kinase AAA_17 PF13207.6 EGF77000.1 - 4.6e-133 438.3 0.3 2e-34 119.0 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_18 PF13238.6 EGF77000.1 - 8.2e-42 142.8 0.0 9.1e-11 42.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_33 PF13671.6 EGF77000.1 - 6.8e-25 87.9 0.0 0.00013 22.2 0.0 6.2 4 2 0 4 4 4 4 AAA domain Zeta_toxin PF06414.12 EGF77000.1 - 2.2e-11 43.4 0.0 0.003 16.9 0.0 4.4 4 0 0 4 4 4 2 Zeta toxin Ploopntkinase3 PF18751.1 EGF77000.1 - 2.4e-11 43.9 0.1 0.055 13.4 0.0 4.4 4 0 0 4 4 4 3 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 EGF77000.1 - 5.1e-11 43.1 0.5 0.29 11.5 0.0 4.5 4 0 0 4 4 4 3 AAA domain Thymidylate_kin PF02223.17 EGF77000.1 - 2e-10 40.7 8.9 1.3 8.7 0.1 6.8 7 0 0 7 7 7 3 Thymidylate kinase Cytidylate_kin PF02224.18 EGF77000.1 - 4e-10 39.8 0.1 0.53 10.0 0.0 4.5 4 0 0 4 4 4 3 Cytidylate kinase AAA PF00004.29 EGF77000.1 - 2.1e-07 31.4 3.8 0.25 11.8 0.0 5.2 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF77000.1 - 5.5e-07 29.9 1.5 4 7.7 0.0 4.8 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.6 EGF77000.1 - 6.8e-06 26.6 0.2 6.4 7.1 0.0 4.5 4 0 0 4 4 4 0 AAA ATPase domain AAA_28 PF13521.6 EGF77000.1 - 7.9e-06 26.2 2.0 5.1 7.3 0.0 4.7 5 0 0 5 5 4 0 AAA domain NTPase_1 PF03266.15 EGF77000.1 - 3.9e-05 23.6 3.6 0.89 9.4 0.0 4.5 4 0 0 4 4 4 1 NTPase NB-ARC PF00931.22 EGF77000.1 - 4.4e-05 22.8 0.3 0.32 10.2 0.0 4.1 4 0 0 4 4 4 1 NB-ARC domain ABC_tran PF00005.27 EGF77000.1 - 7.4e-05 23.3 1.2 2.3 8.8 0.0 4.3 4 0 0 4 4 4 1 ABC transporter Hydin_ADK PF17213.3 EGF77000.1 - 0.00021 21.6 0.0 1.3 9.3 0.0 4.3 5 0 0 5 5 4 1 Hydin Adenylate kinase-like domain ATP_bind_1 PF03029.17 EGF77000.1 - 0.00064 19.6 6.4 7.3 6.3 0.0 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 EGF77000.1 - 0.00086 19.1 0.4 2.9 7.6 0.0 3.7 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EGF77000.1 - 0.0015 17.9 2.6 8 5.6 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGF77000.1 - 0.0016 18.2 0.1 25 4.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 EGF77000.1 - 0.0017 18.1 0.8 23 4.8 0.0 4.3 4 0 0 4 4 4 0 P-loop containing region of AAA domain CobU PF02283.16 EGF77000.1 - 0.0018 17.9 0.1 11 5.5 0.0 4.2 4 0 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Viral_helicase1 PF01443.18 EGF77000.1 - 0.0019 18.0 3.9 10 5.7 0.0 4.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 EGF77000.1 - 0.003 17.2 0.5 38 3.8 0.0 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EGF77000.1 - 0.003 17.9 1.4 29 5.1 0.0 4.6 4 1 0 4 4 4 0 RNA helicase T2SSE PF00437.20 EGF77000.1 - 0.0035 16.4 0.0 19 4.2 0.0 4.1 4 0 0 4 4 4 0 Type II/IV secretion system protein DUF5582 PF17819.1 EGF77000.1 - 0.0044 17.5 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5582) NACHT PF05729.12 EGF77000.1 - 0.0046 16.9 7.0 2 8.3 0.0 4.9 5 0 0 5 5 4 1 NACHT domain KTI12 PF08433.10 EGF77000.1 - 0.011 15.2 1.2 22 4.4 0.0 4.0 4 0 0 4 4 4 0 Chromatin associated protein KTI12 ATPase PF06745.13 EGF77000.1 - 0.019 14.3 3.0 27 4.0 0.1 4.4 4 1 0 4 4 4 0 KaiC TIP49 PF06068.13 EGF77000.1 - 0.035 13.3 0.0 7.2 5.7 0.0 2.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 EGF77000.1 - 0.049 13.3 0.9 54 3.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 EGF77000.1 - 0.076 12.0 1.9 33 3.3 0.0 3.8 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB dNK PF01712.19 EGF77000.1 - 0.11 12.3 6.8 6.4 6.6 0.0 4.6 7 0 0 7 7 4 0 Deoxynucleoside kinase Thermopsin PF05317.11 EGF77000.1 - 0.12 11.8 0.0 83 2.5 0.0 3.5 4 0 0 4 4 4 0 Thermopsin PduV-EutP PF10662.9 EGF77000.1 - 0.37 10.5 1.5 49 3.6 0.0 3.8 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation Sec5 PF15469.6 EGF77001.1 - 2.4e-54 184.0 0.6 5.8e-53 179.5 0.0 3.0 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 EGF77001.1 - 0.0019 18.3 0.5 0.0061 16.6 0.1 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Yopt PF09467.10 EGF77001.1 - 0.016 15.2 0.1 0.067 13.3 0.1 2.0 1 0 0 1 1 1 0 Hypothetical protein Yopt Voldacs PF03517.13 EGF77002.1 - 9.8e-33 113.2 0.4 1.9e-32 112.3 0.4 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Flavoprotein PF02441.19 EGF77003.1 - 5.1e-53 179.1 0.6 5.7e-53 178.9 0.6 1.0 1 0 0 1 1 1 1 Flavoprotein vATP-synt_AC39 PF01992.16 EGF77004.1 - 1.9e-116 389.3 0.9 2.1e-116 389.1 0.9 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Xpo1 PF08389.12 EGF77005.1 - 1.4e-12 47.9 0.3 1.4e-12 47.9 0.3 5.6 5 2 1 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 EGF77005.1 - 0.023 14.6 0.7 0.078 12.9 0.7 2.0 1 0 0 1 1 1 0 Importin-beta N-terminal domain DUF484 PF04340.12 EGF77005.1 - 0.025 14.3 1.4 0.15 11.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DUF3385 PF11865.8 EGF77005.1 - 0.7 9.8 6.4 2.4 8.1 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Cpn60_TCP1 PF00118.24 EGF77006.1 - 1.1e-156 522.3 19.5 1.3e-156 522.1 19.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EGF77006.1 - 0.014 14.9 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Telomere recombination SCAB_CC PF16712.5 EGF77006.1 - 0.35 10.7 3.8 0.13 12.1 0.5 1.9 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein ParA PF10609.9 EGF77008.1 - 1.7e-98 329.0 2.4 2.1e-98 328.7 2.4 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGF77008.1 - 6.5e-13 48.9 0.1 1.3e-12 47.9 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGF77008.1 - 9.2e-12 45.2 2.8 8e-10 38.9 2.8 2.3 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EGF77008.1 - 4.5e-11 42.5 0.0 6.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 EGF77008.1 - 3.6e-09 36.4 0.2 2.9e-05 23.7 0.1 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EGF77008.1 - 4.6e-07 29.3 1.2 6.6e-05 22.2 0.5 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase VirC1 PF07015.11 EGF77008.1 - 0.00011 21.6 0.1 0.00026 20.4 0.1 1.6 2 0 0 2 2 2 1 VirC1 protein MeaB PF03308.16 EGF77008.1 - 0.0032 16.5 0.2 0.0052 15.8 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EGF77008.1 - 0.011 15.3 0.4 0.046 13.2 0.1 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EGF77008.1 - 0.025 14.2 2.0 0.031 13.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain DUF5305 PF17231.2 EGF77008.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) FTHFS PF01268.19 EGF77008.1 - 0.13 10.4 0.1 0.19 9.9 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase SRP54 PF00448.22 EGF77008.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf_C2H2_10 PF18414.1 EGF77008.1 - 1.6 8.4 4.7 3.1 7.4 4.7 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger DUF4564 PF15169.6 EGF77009.1 - 2.3e-07 30.7 0.1 6e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4564) DUF2484 PF10658.9 EGF77009.1 - 0.029 14.7 0.2 0.047 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) DUF3336 PF11815.8 EGF77010.1 - 1.5e-35 121.9 3.5 3.7e-35 120.6 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGF77010.1 - 4.7e-18 66.1 0.0 1.6e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase PHD_like PF12910.7 EGF77010.1 - 0.028 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system RRM_1 PF00076.22 EGF77011.1 - 3.8e-19 68.3 0.0 5.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF77011.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EGF77011.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EGF77011.1 - 0.031 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain Syja_N PF02383.18 EGF77012.1 - 5.4e-53 180.4 0.2 7.7e-53 179.9 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain HLH PF00010.26 EGF77013.1 - 4.4e-13 49.0 0.3 8.5e-13 48.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.12 EGF77013.1 - 0.011 15.5 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein DEAD PF00270.29 EGF77014.1 - 6.9e-52 175.7 0.0 3.7e-50 170.1 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF77014.1 - 9.3e-28 96.8 0.0 1.2e-26 93.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF77014.1 - 0.0039 17.2 0.0 0.026 14.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1003 PF06210.11 EGF77015.1 - 8.5e-31 106.1 0.0 1.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) Glyco_hydro_18 PF00704.28 EGF77016.1 - 5.9e-11 42.7 1.5 8.9e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 EGF77017.1 - 7.5e-11 42.3 1.8 9.2e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 PLU-1 PF08429.11 EGF77019.1 - 1.7e-56 191.9 4.4 9.2e-56 189.4 4.1 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 EGF77019.1 - 3.3e-42 143.5 1.8 1e-41 141.9 1.8 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EGF77019.1 - 2.1e-23 82.0 61.3 2.1e-10 40.3 7.3 5.5 6 0 0 6 6 6 3 PHD-finger ARID PF01388.21 EGF77019.1 - 9.9e-22 77.4 0.1 2.6e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EGF77019.1 - 2.7e-14 52.8 0.1 6e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EGF77019.1 - 9.7e-14 51.5 12.6 9.7e-14 51.5 12.6 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.6 EGF77019.1 - 2.2e-05 23.9 1.8 2.2e-05 23.9 1.8 4.2 4 0 0 4 4 4 3 PHD-finger C1_2 PF03107.16 EGF77019.1 - 0.0095 16.2 1.7 0.0095 16.2 1.7 5.6 6 0 0 6 6 6 1 C1 domain C1_1 PF00130.22 EGF77019.1 - 0.12 12.2 43.7 0.023 14.6 4.1 5.0 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 EGF77019.1 - 2.8 8.1 30.0 2.2 8.4 5.5 4.2 3 1 0 3 3 3 0 PHD-finger Scs3p PF10261.9 EGF77020.1 - 1.1e-33 116.8 21.5 4.6e-32 111.5 21.5 2.1 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 EGF77020.1 - 0.57 9.9 12.7 1.7 8.4 12.7 2.0 1 1 0 1 1 1 0 PAP2 superfamily ARL6IP6 PF15062.6 EGF77021.1 - 0.087 13.0 0.7 0.15 12.2 0.2 1.7 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix USP7_ICP0_bdg PF12436.8 EGF77022.1 - 6.2e-69 232.0 0.0 7.5e-67 225.1 0.0 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGF77022.1 - 3.5e-56 190.2 0.4 5.6e-54 183.0 0.0 2.9 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGF77022.1 - 4.5e-46 157.4 0.1 7.2e-46 156.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF77022.1 - 2.6e-18 66.7 0.0 2.6e-17 63.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RGS12_usC PF16612.5 EGF77022.1 - 0.091 13.2 0.6 3 8.3 0.3 2.3 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 ubiquitin PF00240.23 EGF77022.1 - 0.17 11.7 0.0 1 9.1 0.0 2.4 1 0 0 1 1 1 0 Ubiquitin family OFCC1 PF15680.5 EGF77023.1 - 0.2 12.2 5.4 1.7 9.2 1.8 2.6 1 1 0 2 2 2 0 Orofacial cleft 1 candidate gene 1 protein PUF PF00806.19 EGF77024.1 - 3e-24 83.3 0.0 6e-06 25.7 0.0 7.9 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Mt_ATP-synt_D PF05873.12 EGF77025.1 - 3.6e-18 65.9 5.8 4.8e-18 65.5 5.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TFA2_Winged_2 PF18121.1 EGF77025.1 - 0.0065 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 AcetDehyd-dimer PF09290.11 EGF77025.1 - 0.021 15.0 0.8 0.38 10.9 0.7 2.1 1 1 1 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Calici_coat_C PF08435.11 EGF77025.1 - 0.027 14.0 0.1 0.037 13.6 0.1 1.2 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal MCRS_N PF13325.6 EGF77025.1 - 0.044 13.8 2.2 0.091 12.8 0.9 1.8 1 1 1 2 2 2 0 N-terminal region of micro-spherule protein ESP PF16590.5 EGF77025.1 - 0.065 13.5 0.5 0.15 12.4 0.5 1.6 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Crinivirus_P26 PF07416.11 EGF77025.1 - 0.076 12.7 0.2 0.098 12.4 0.2 1.1 1 0 0 1 1 1 0 Crinivirus P26 protein Spectrin PF00435.21 EGF77025.1 - 0.084 13.4 3.9 0.42 11.1 2.2 2.0 1 1 1 2 2 2 0 Spectrin repeat Cyc-maltodext_C PF10438.9 EGF77025.1 - 0.11 12.6 0.6 0.21 11.7 0.3 1.7 1 1 1 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain GNT-I PF03071.15 EGF77025.1 - 0.14 10.9 2.2 0.17 10.7 2.2 1.1 1 0 0 1 1 1 0 GNT-I family Vac_ImportDeg PF09783.9 EGF77026.1 - 1.2e-47 161.8 1.4 1.3e-47 161.6 1.4 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein HicA_toxin PF07927.12 EGF77026.1 - 0.12 12.4 0.3 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, FAT PF02259.23 EGF77027.1 - 5.7e-111 371.1 1.0 1.5e-110 369.7 0.1 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGF77027.1 - 2.7e-72 243.6 0.1 6.6e-72 242.3 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGF77027.1 - 3.4e-59 199.4 1.4 3.3e-55 186.4 0.1 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGF77027.1 - 5.7e-45 151.8 0.3 2.9e-44 149.5 0.3 2.4 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 EGF77027.1 - 2.1e-15 56.2 0.2 2.1e-15 56.2 0.2 2.7 3 0 0 3 3 2 1 FATC domain HEAT_2 PF13646.6 EGF77027.1 - 2.4e-12 47.1 18.1 0.0014 19.0 0.0 8.5 7 1 1 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 EGF77027.1 - 7.5e-08 32.7 28.7 1.2 9.8 0.4 12.1 11 2 3 14 14 14 4 HEAT-like repeat HEAT PF02985.22 EGF77027.1 - 1.8e-05 24.6 27.6 3.5 8.1 0.0 12.4 13 0 0 13 13 13 1 HEAT repeat IFRD PF05004.13 EGF77027.1 - 0.00066 18.9 9.9 0.42 9.7 0.0 5.2 3 1 2 5 5 5 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 EGF77027.1 - 0.002 18.2 10.9 1.8 8.6 0.1 6.0 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 EGF77027.1 - 0.0071 16.8 0.0 0.43 11.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Sec7_N PF12783.7 EGF77027.1 - 0.016 15.1 12.1 0.26 11.2 0.0 5.2 3 2 2 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.6 EGF77027.1 - 0.051 13.6 0.2 15 5.8 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF77027.1 - 0.056 14.1 0.1 0.29 11.8 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Tti2 PF10521.9 EGF77027.1 - 0.093 12.2 5.3 15 5.0 0.0 4.0 2 1 1 3 3 3 0 Tti2 family GTP_EFTU PF00009.27 EGF77030.1 - 6.4e-58 195.5 0.2 8.5e-58 195.1 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGF77030.1 - 1.2e-28 99.6 0.1 3.2e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGF77030.1 - 2.1e-16 60.0 0.9 5.1e-16 58.8 0.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF77030.1 - 1.6e-05 24.9 0.0 8.6e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF77030.1 - 0.0037 17.2 0.2 0.0095 15.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EGF77030.1 - 0.0073 15.9 0.1 0.0073 15.9 0.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EGF77030.1 - 0.026 14.3 0.4 6.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation LRR_9 PF14580.6 EGF77031.1 - 2.6e-55 186.6 1.8 3.9e-55 186.0 1.8 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EGF77031.1 - 1.2e-10 41.0 17.6 2.4e-09 36.8 5.0 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGF77031.1 - 1.1e-08 35.2 15.3 0.00026 21.3 3.3 3.5 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF77031.1 - 0.0086 16.5 7.2 2 9.3 1.0 4.2 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 EGF77031.1 - 0.11 12.6 5.2 8.4 6.7 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_2 PF07723.13 EGF77031.1 - 3.5 8.4 5.4 3.1 8.6 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat GRP PF07172.11 EGF77032.1 - 0.00033 21.3 1.8 0.0004 21.0 1.8 1.1 1 0 0 1 1 1 1 Glycine rich protein family Glyco_hydro_85 PF03644.13 EGF77033.1 - 2.4e-65 221.0 2.7 7.4e-65 219.3 2.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 85 EBP PF05241.12 EGF77034.1 - 1.3e-44 151.8 6.6 1.8e-44 151.3 6.6 1.2 1 0 0 1 1 1 1 Emopamil binding protein Cnd3 PF12719.7 EGF77034.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain AAA PF00004.29 EGF77036.1 - 0.076 13.4 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NMT1 PF09084.11 EGF77036.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Peptidase_M36 PF02128.15 EGF77038.1 - 1.6e-77 261.2 0.2 1.8e-77 261.0 0.2 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) MR_MLE_N PF02746.16 EGF77038.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1505 PF07403.11 EGF77039.1 - 0.38 11.0 3.9 0.74 10.0 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1505) DUF4692 PF15763.5 EGF77039.1 - 7.3 7.0 9.0 0.81 10.1 4.5 1.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Asp PF00026.23 EGF77041.1 - 6.2e-09 35.7 0.0 9.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77041.1 - 9.3e-06 25.5 0.1 3.2e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PAG PF15347.6 EGF77044.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched AP3D1 PF06375.11 EGF77046.1 - 0.0092 16.2 4.6 0.0092 16.2 4.6 2.0 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 Spc7 PF08317.11 EGF77046.1 - 0.029 13.3 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PBP1_TM PF14812.6 EGF77046.1 - 0.36 11.2 7.3 0.86 10.0 7.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Retrotran_gag_2 PF14223.6 EGF77047.1 - 0.0015 18.2 1.1 0.0026 17.4 1.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 EGF77047.1 - 0.013 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain Arm-DNA-bind_4 PF14657.6 EGF77049.1 - 0.032 14.0 0.1 0.077 12.8 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain DUF1283 PF06932.11 EGF77049.1 - 0.044 14.0 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) DUF3422 PF11902.8 EGF77049.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF4246 PF14033.6 EGF77051.1 - 1.9e-80 271.2 0.2 2.1e-80 271.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Transposase_24 PF03004.14 EGF77052.1 - 0.0036 17.4 0.3 0.0036 17.4 0.3 2.1 2 0 0 2 2 2 1 Plant transposase (Ptta/En/Spm family) MF_alpha_N PF05436.11 EGF77052.1 - 0.0062 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus DUF3450 PF11932.8 EGF77052.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Chromo_shadow PF01393.19 EGF77053.1 - 1.3e-20 73.2 2.6 3.5e-18 65.4 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGF77053.1 - 4.4e-11 42.5 0.7 4.4e-11 42.5 0.7 2.5 3 1 1 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain PPL5 PF18168.1 EGF77053.1 - 0.71 9.1 5.1 0.62 9.3 3.9 1.6 1 1 1 2 2 2 0 Prim-pol family 5 DUF648 PF04890.13 EGF77054.1 - 0.021 14.6 0.3 0.021 14.6 0.3 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF648) Pox_A11 PF05061.13 EGF77054.1 - 0.068 12.4 0.1 0.082 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF5323 PF17257.2 EGF77054.1 - 0.56 10.1 4.5 1.3 8.9 4.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5323) Cyclin PF08613.11 EGF77054.1 - 1.2 9.4 6.3 14 6.0 2.0 2.8 1 1 1 2 2 2 0 Cyclin DUF4834 PF16118.5 EGF77054.1 - 3.3 8.7 10.5 0.6 11.1 2.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 EGF77055.1 - 4.1e-63 213.2 0.1 5e-63 212.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77055.1 - 1.4e-18 67.1 0.0 2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF77055.1 - 2.8e-06 27.5 0.1 2.1e-05 24.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF77055.1 - 0.0041 16.0 0.1 0.013 14.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGF77055.1 - 0.0051 16.2 0.0 0.0092 15.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF77055.1 - 0.013 14.9 0.2 0.022 14.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF77055.1 - 0.031 13.8 0.1 0.031 13.8 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DnaJ PF00226.31 EGF77056.1 - 1.4e-23 82.8 0.3 4.8e-23 81.1 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EGF77056.1 - 2.9e-09 37.0 1.3 1.4e-08 34.8 1.3 2.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGF77056.1 - 2.2e-05 24.9 2.2 0.12 13.3 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF77056.1 - 6.1e-05 23.3 4.8 0.043 14.3 0.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 EGF77056.1 - 9.7e-05 22.6 1.4 9.7e-05 22.6 1.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGF77056.1 - 0.00042 20.6 13.8 0.011 16.1 0.5 4.0 4 1 1 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.19 EGF77056.1 - 0.0035 17.7 0.4 0.14 12.5 0.4 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Glyco_tranf_2_4 PF13704.6 EGF77056.1 - 0.0036 17.8 1.5 0.017 15.7 0.7 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 dCMP_cyt_deam_1 PF00383.23 EGF77056.1 - 0.016 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region STI1 PF17830.1 EGF77056.1 - 0.032 14.2 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 STI1 domain Chitin_synth_2 PF03142.15 EGF77057.1 - 3.5e-30 105.1 5.8 3.5e-30 105.1 5.8 3.0 3 0 0 3 3 3 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGF77057.1 - 4.3e-18 65.9 6.8 4.3e-18 65.9 6.8 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF77057.1 - 1.1e-10 41.8 0.0 2.7e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF77057.1 - 1.3e-05 24.7 0.0 6.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF77057.1 - 8.6e-05 22.4 0.0 0.0014 18.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Thioredoxin PF00085.20 EGF77060.1 - 0.00069 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin PT PF04886.12 EGF77061.1 - 0.0024 17.4 0.9 0.0024 17.4 0.9 1.7 2 0 0 2 2 2 1 PT repeat PIG-Y PF15159.6 EGF77061.1 - 0.019 15.9 1.0 0.037 15.0 1.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y SOG2 PF10428.9 EGF77062.1 - 1 8.5 7.1 1.1 8.4 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Toxin_7 PF05980.12 EGF77062.1 - 1.7 8.9 6.6 5.8 7.2 1.0 2.5 2 0 0 2 2 2 0 Toxin 7 Toxin_12 PF07740.12 EGF77062.1 - 5 7.9 6.2 0.71 10.6 0.6 2.3 2 1 0 2 2 2 0 Ion channel inhibitory toxin IGFBP PF00219.18 EGF77062.1 - 9.9 6.9 10.0 1.1e+02 3.5 1.9 2.4 1 1 1 2 2 2 0 Insulin-like growth factor binding protein bZIP_1 PF00170.21 EGF77063.1 - 3.9e-08 33.3 7.0 7.5e-08 32.4 7.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGF77063.1 - 5e-05 23.3 7.2 0.0001 22.3 7.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper ASD2 PF08687.11 EGF77063.1 - 0.066 12.8 7.8 0.03 13.9 4.7 1.9 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 RuvC_1 PF18516.1 EGF77063.1 - 0.079 12.1 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 RuvC nuclease domain SBP_bac_8 PF13416.6 EGF77065.1 - 4.3e-09 36.6 0.6 6.3e-09 36.1 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EGF77065.1 - 0.00054 20.0 0.1 0.001 19.1 0.1 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Phage_ABA_S PF18066.1 EGF77065.1 - 0.027 15.2 0.0 0.11 13.2 0.0 2.0 2 0 0 2 2 2 0 Phage ABA sandwich domain Ribonuc_2-5A PF06479.12 EGF77066.1 - 9.7e-39 132.4 0.0 1.3e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EGF77066.1 - 2.8e-24 85.9 0.0 4.2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77066.1 - 1.5e-12 47.3 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77066.1 - 0.035 12.9 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sec10 PF07393.11 EGF77067.1 - 5.5e-170 567.2 10.3 7.4e-170 566.8 10.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 tRNA-synt_1b PF00579.25 EGF77068.1 - 6.4e-72 242.3 0.0 8.1e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 EGF77068.1 - 2.5e-28 98.0 0.1 5.8e-28 96.8 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain NAD_binding_7 PF13241.6 EGF77068.1 - 0.13 12.7 0.0 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding COG7 PF10191.9 EGF77069.1 - 1.5e-60 205.3 25.8 6.4e-58 196.7 18.2 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) CPDase PF07823.11 EGF77069.1 - 0.046 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein eIF-5_eIF-2B PF01873.17 EGF77070.1 - 7.4e-41 138.7 0.1 1.8e-40 137.4 0.0 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 EGF77070.1 - 1.2e-21 76.6 1.0 3e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HEAT_2 PF13646.6 EGF77070.1 - 0.066 13.6 3.7 3.7 8.0 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats DUF3797 PF12677.7 EGF77070.1 - 0.087 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Peptidase_Mx1 PF15890.5 EGF77072.1 - 0.0076 15.7 0.3 0.014 14.8 0.3 1.6 1 1 0 1 1 1 1 Putative zinc-binding metallo-peptidase HARP PF07443.13 EGF77073.1 - 0.13 11.9 1.5 0.35 10.5 1.1 2.0 1 1 0 1 1 1 0 HepA-related protein (HARP) Na_H_Exchanger PF00999.21 EGF77075.1 - 4.4e-61 206.8 41.9 5.7e-61 206.4 41.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-C2H2 PF00096.26 EGF77077.1 - 0.002 18.5 0.7 0.0045 17.4 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type SANTA PF09133.10 EGF77078.1 - 0.0056 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 SANTA (SANT Associated) Homeodomain PF00046.29 EGF77079.1 - 8.8e-11 41.5 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGF77079.1 - 0.0012 18.7 0.1 0.0026 17.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain C1-set PF07654.15 EGF77079.1 - 0.079 13.4 0.1 0.14 12.5 0.1 1.6 1 1 0 1 1 1 0 Immunoglobulin C1-set domain WbqC PF08889.11 EGF77079.1 - 0.088 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 WbqC-like protein family zf-ANAPC11 PF12861.7 EGF77080.1 - 9.4e-20 70.5 8.9 1.2e-19 70.2 8.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGF77080.1 - 1.4e-12 47.7 13.2 4.8e-12 46.0 13.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGF77080.1 - 5.6e-07 29.8 13.1 8.3e-07 29.2 13.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGF77080.1 - 0.00072 19.4 13.6 0.0032 17.3 13.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF77080.1 - 0.00093 18.9 15.5 0.0014 18.3 15.5 1.2 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGF77080.1 - 0.0029 17.2 12.5 0.0029 17.2 12.5 1.9 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EGF77080.1 - 0.024 14.7 4.9 0.035 14.2 4.9 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_UBOX PF13445.6 EGF77080.1 - 0.027 14.5 14.6 0.04 13.9 14.6 1.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGF77080.1 - 0.042 13.7 17.1 1.1 9.1 17.1 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF77080.1 - 0.16 12.0 13.3 0.44 10.5 13.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 EGF77080.1 - 1.3 9.2 12.8 10 6.4 12.8 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGF77080.1 - 2.6 8.4 13.1 18 5.7 13.1 2.3 1 1 0 1 1 1 0 RING-like domain PGI PF00342.19 EGF77081.1 - 4.3e-242 803.9 1.5 4.9e-242 803.8 1.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MAF_flag10 PF01973.18 EGF77081.1 - 0.097 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 Peptidase_C23 PF05379.11 EGF77084.1 - 0.038 14.1 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 Carlavirus endopeptidase zf-C3HC4_3 PF13920.6 EGF77085.1 - 0.00056 19.7 8.9 0.0016 18.3 8.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF77085.1 - 0.00095 19.4 10.7 0.0024 18.2 10.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGF77085.1 - 0.24 11.3 7.7 0.79 9.6 7.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF77085.1 - 1.3 9.0 7.8 2.5 8.1 7.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EGF77085.1 - 4.9 7.1 15.7 51 3.8 0.5 3.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 HA2 PF04408.23 EGF77086.1 - 1.1e-20 73.9 0.0 2.7e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGF77086.1 - 1.7e-11 44.4 0.0 3.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGF77086.1 - 9.5e-08 32.0 0.1 2.4e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF77086.1 - 0.00013 22.3 0.2 0.00039 20.7 0.2 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGF77086.1 - 0.00021 20.4 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 EGF77086.1 - 0.0063 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_30 PF13604.6 EGF77086.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGF77086.1 - 0.013 15.8 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGF77086.1 - 0.025 14.1 0.1 0.13 11.7 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein DUF2075 PF09848.9 EGF77086.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EGF77086.1 - 0.071 13.3 0.9 0.26 11.5 0.1 2.5 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 EGF77086.1 - 0.11 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 EGF77087.1 - 8e-78 261.4 0.0 9.7e-78 261.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77087.1 - 1.3e-45 155.8 0.0 1.6e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77087.1 - 1.7e-07 30.9 0.0 3.4e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF77087.1 - 0.0001 22.0 0.6 0.00016 21.3 0.6 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGF77087.1 - 0.00049 20.1 0.0 0.93 9.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGF77087.1 - 0.002 17.5 0.5 0.0039 16.6 0.5 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF77087.1 - 0.011 14.6 0.4 0.026 13.5 0.4 1.6 1 1 0 1 1 1 0 Haspin like kinase domain KA1 PF02149.19 EGF77088.1 - 7.9e-19 67.2 0.0 1.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 EAF PF09816.9 EGF77089.1 - 1e-15 58.0 0.0 2.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor SLM4 PF16818.5 EGF77090.1 - 0.026 14.5 1.7 5.5 6.9 0.3 2.8 2 0 0 2 2 2 0 Protein SLM4 DUF2935 PF11155.8 EGF77090.1 - 0.11 12.8 0.1 0.41 11.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Nodulin-like PF06813.13 EGF77091.1 - 6.3e-17 61.9 13.1 6.3e-17 61.9 13.1 2.2 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.16 EGF77091.1 - 2.4e-16 59.6 34.0 2.4e-16 59.6 34.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily NDT80_PhoG PF05224.12 EGF77093.1 - 4.9e-28 98.6 0.0 1.2e-27 97.3 0.0 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GDP_Man_Dehyd PF16363.5 EGF77094.1 - 3.8e-54 184.3 0.0 1e-53 182.9 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGF77094.1 - 7.5e-53 179.5 0.0 9.8e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF77094.1 - 3.3e-18 65.7 0.0 6.6e-18 64.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGF77094.1 - 1.5e-15 57.1 0.0 9.4e-15 54.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGF77094.1 - 5.9e-15 55.1 0.0 8.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGF77094.1 - 3.8e-10 40.0 0.0 6.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGF77094.1 - 3.1e-09 36.8 0.0 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 EGF77094.1 - 8.2e-06 25.2 0.0 0.0024 17.1 0.0 2.8 1 1 1 2 2 2 2 Male sterility protein KR PF08659.10 EGF77094.1 - 0.0026 17.7 0.2 0.068 13.1 0.2 2.7 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 EGF77094.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_17 PF12692.7 EGF77094.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DapB_N PF01113.20 EGF77094.1 - 0.041 14.0 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.6 EGF77095.1 - 2.9e-44 151.4 0.7 4.3e-44 150.8 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF77095.1 - 1.3e-42 145.5 2.6 2.1e-42 144.8 2.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF77095.1 - 9.5e-08 32.2 0.2 1.7e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF77095.1 - 6.1e-05 22.6 0.4 0.0014 18.1 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EGF77095.1 - 0.023 14.7 0.3 0.05 13.7 0.3 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EGF77095.1 - 0.058 12.7 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EGF77095.1 - 0.11 11.9 0.1 8.8 5.6 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 EGF77095.1 - 0.15 12.5 0.2 0.55 10.7 0.4 1.7 2 1 0 2 2 2 0 Putative NAD(P)-binding UCH PF00443.29 EGF77096.1 - 2.5e-45 155.0 0.3 3.9e-45 154.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGF77096.1 - 2.9e-14 53.1 3.3 7.6e-14 51.8 3.3 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGF77096.1 - 2.7e-08 33.8 11.6 0.0018 17.9 0.1 3.8 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.16 EGF77097.1 - 2.1e-09 36.9 0.0 3.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EGF77097.1 - 3.5e-06 26.5 2.3 5.4e-06 25.9 2.3 1.3 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 EGF77097.1 - 0.0016 18.5 0.3 0.0027 17.7 0.3 1.3 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 ADK PF00406.22 EGF77099.1 - 1.4e-24 86.9 0.0 1.6e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGF77099.1 - 8.3e-07 29.5 0.0 1.8e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain WD40 PF00400.32 EGF77100.1 - 1.1e-20 73.6 12.3 3.9e-08 33.8 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77100.1 - 2.4e-07 30.9 0.2 0.014 15.7 0.1 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGF77100.1 - 0.00014 21.1 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.8 EGF77100.1 - 0.00052 18.8 1.1 0.0012 17.6 0.1 1.9 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGF77100.1 - 0.0014 17.4 0.9 0.0088 14.8 0.2 2.3 1 1 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.6 EGF77100.1 - 0.0081 16.2 0.1 0.11 12.6 0.0 2.4 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Acyl-CoA_dh_1 PF00441.24 EGF77101.1 - 4e-36 124.5 0.3 7.5e-36 123.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EGF77101.1 - 9.3e-19 67.3 0.0 2.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EGF77101.1 - 1.3e-18 67.0 0.1 2.2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGF77101.1 - 2.5e-13 50.6 0.0 7e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF77101.1 - 4.2e-06 27.1 0.0 7.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fimbrial_K88 PF02432.15 EGF77101.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 1 Fimbrial, major and minor subunit SPICE PF15678.5 EGF77101.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression LRR_6 PF13516.6 EGF77102.1 - 4e-12 45.2 12.2 0.001 19.0 1.6 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 EGF77102.1 - 0.006 16.3 9.6 0.17 11.7 0.3 4.0 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EGF77102.1 - 0.41 11.4 8.6 29 5.7 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat Peptidase_M36 PF02128.15 EGF77103.1 - 4.2e-66 223.6 0.5 4.7e-66 223.4 0.5 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) DUF4558 PF15104.6 EGF77104.1 - 5.2 7.2 10.4 0.47 10.5 1.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4558) Pkinase_Tyr PF07714.17 EGF77105.1 - 1.4e-24 86.8 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGF77105.1 - 1.3e-17 64.1 0.0 2.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGF77105.1 - 0.024 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ABC_tran_CTD PF16326.5 EGF77106.1 - 1.3 9.3 7.5 0.41 10.9 0.3 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF5126 PF17166.4 EGF77107.1 - 0.14 12.1 1.7 0.46 10.4 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5126) Peptidase_M36 PF02128.15 EGF77108.1 - 7.5e-137 456.4 0.5 8.5e-137 456.2 0.5 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 EGF77108.1 - 0.1 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like APG6_N PF17675.1 EGF77109.1 - 3.8e-06 27.5 22.2 0.00014 22.4 5.3 2.3 2 0 0 2 2 2 2 Apg6 coiled-coil region V_ATPase_I PF01496.19 EGF77109.1 - 0.0055 14.7 14.6 0.0082 14.1 3.7 2.1 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF4062 PF13271.6 EGF77109.1 - 0.03 14.7 0.6 22 5.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) PEP-utilisers_N PF05524.13 EGF77109.1 - 0.052 13.7 13.7 1.3 9.2 0.1 3.3 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal BBS1 PF14779.6 EGF77109.1 - 0.26 10.7 5.4 0.16 11.4 0.4 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Flg_hook PF02120.16 EGF77109.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.9 3 1 1 4 4 4 0 Flagellar hook-length control protein FliK COG2 PF06148.11 EGF77109.1 - 0.48 10.5 8.8 1 9.4 0.8 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RMI1_C PF16099.5 EGF77109.1 - 1 9.2 10.2 0.64 9.8 0.8 3.2 3 0 0 3 3 3 0 Recq-mediated genome instability protein 1, C-terminal OB-fold JIP_LZII PF16471.5 EGF77109.1 - 1 9.6 15.5 2 8.6 0.3 4.1 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II IL10 PF00726.17 EGF77109.1 - 1.4 8.4 4.2 6.1 6.3 0.2 3.3 2 2 3 5 5 5 0 Interleukin 10 TarH PF02203.15 EGF77109.1 - 1.7 8.5 15.1 4.5 7.1 5.7 3.2 2 1 1 3 3 3 0 Tar ligand binding domain homologue CLTH PF10607.9 EGF77109.1 - 2.5 8.0 6.7 0.98 9.3 0.3 2.8 2 1 0 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain YtxH PF12732.7 EGF77109.1 - 5.2 7.7 16.6 0.89 10.1 4.0 3.3 2 1 0 2 2 2 0 YtxH-like protein YabA PF06156.13 EGF77109.1 - 5.8 7.6 20.1 0.34 11.6 2.5 3.7 1 1 2 3 3 3 0 Initiation control protein YabA SLATT_4 PF18186.1 EGF77109.1 - 6.7 6.3 8.0 9.6 5.8 0.2 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 PHM7_cyt PF14703.6 EGF77109.1 - 7.3 6.8 16.9 0.17 12.1 0.6 3.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4246 PF14033.6 EGF77110.1 - 8.7e-81 272.3 0.1 9.7e-81 272.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) WD40 PF00400.32 EGF77111.1 - 5.8e-17 61.8 14.0 1.1e-06 29.2 0.2 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77111.1 - 9e-08 32.3 0.1 0.0032 17.7 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Aminotran_1_2 PF00155.21 EGF77112.1 - 1.7e-57 195.3 0.0 2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGF77112.1 - 1.7e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EGF77112.1 - 0.0003 19.6 0.0 0.00097 18.0 0.0 1.7 1 1 1 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 EGF77112.1 - 0.00066 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGF77112.1 - 0.0069 15.0 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGF77112.1 - 0.0096 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V TetR_C_14 PF17754.1 EGF77112.1 - 0.097 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 MftR C-terminal domain CTP_transf_like PF01467.26 EGF77113.1 - 6.6e-05 23.1 0.0 0.047 13.9 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase-like Hist_deacetyl PF00850.19 EGF77114.1 - 9.8e-75 251.9 0.5 1.1e-74 251.7 0.5 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Vac14_Fig4_bd PF11916.8 EGF77115.1 - 2.8e-81 271.5 4.8 6.3e-81 270.3 4.8 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGF77115.1 - 1.1e-43 147.8 0.6 5.9e-38 129.4 0.0 4.2 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGF77115.1 - 1.3e-14 53.0 0.9 0.002 18.2 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 EGF77115.1 - 4.4e-08 33.3 6.0 0.0067 16.5 0.8 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF77115.1 - 4.9e-08 33.2 1.7 0.29 11.5 0.0 5.3 5 0 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 EGF77115.1 - 7e-07 29.6 0.6 0.011 16.2 0.0 4.1 5 0 0 5 5 5 2 HEAT-like repeat Arm PF00514.23 EGF77115.1 - 0.002 18.1 0.1 10 6.3 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 EGF77115.1 - 0.0068 15.6 2.4 1.3 8.0 0.1 3.1 3 0 0 3 3 3 2 Dopey, N-terminal MMS19_C PF12460.8 EGF77115.1 - 0.013 14.6 4.0 0.15 11.2 0.0 3.6 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal ThylakoidFormat PF11264.8 EGF77115.1 - 0.033 13.9 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Thylakoid formation protein Pab87_oct PF13969.6 EGF77119.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Pab87 octamerisation domain DUF1221 PF06760.11 EGF77119.1 - 0.2 11.1 5.7 0.29 10.6 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) DUF4246 PF14033.6 EGF77122.1 - 9.4e-30 104.1 0.0 1.2e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Epiglycanin_TR PF05647.11 EGF77123.1 - 0.25 11.3 17.4 0.43 10.5 17.4 1.4 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like CHD5 PF04420.14 EGF77123.1 - 0.71 9.7 2.3 0.79 9.6 0.6 1.9 1 1 1 2 2 2 0 CHD5-like protein DUF2642 PF10842.8 EGF77124.1 - 0.14 12.0 2.1 8.3 6.3 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2642) Peptidase_S41 PF03572.18 EGF77125.1 - 4e-12 46.0 0.0 8.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 AAA_16 PF13191.6 EGF77127.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 EGF77127.1 - 0.093 12.5 0.0 0.73 9.5 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SCAMP PF04144.13 EGF77128.1 - 5.4e-47 160.3 15.2 6.4e-47 160.1 15.2 1.1 1 0 0 1 1 1 1 SCAMP family SPOC PF07744.13 EGF77129.1 - 2.5e-07 30.7 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 SPOC domain RRM_1 PF00076.22 EGF77129.1 - 9.4e-07 28.6 0.1 0.0015 18.3 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4246 PF14033.6 EGF77130.1 - 1.9e-80 271.2 1.0 2.1e-80 271.0 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF1221 PF06760.11 EGF77131.1 - 0.062 12.8 4.5 0.09 12.3 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Collagen_bind_2 PF12904.7 EGF77131.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Endonuclease_NS PF01223.23 EGF77133.1 - 1.4e-44 152.6 0.1 1.9e-44 152.2 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Uso1_p115_head PF04869.14 EGF77134.1 - 4.5e-82 275.7 0.0 4.5e-82 275.7 0.0 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EGF77134.1 - 1.7e-08 34.9 13.8 2.8e-08 34.2 13.8 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 EGF77134.1 - 2.9e-07 30.3 0.3 2.9e-07 30.3 0.3 2.5 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor Cortex-I_coil PF09304.10 EGF77134.1 - 0.037 14.3 6.6 0.11 12.8 6.6 1.8 1 0 0 1 1 1 0 Cortexillin I, coiled coil CC2-LZ PF16516.5 EGF77134.1 - 0.16 12.3 9.6 0.43 11.0 9.6 1.7 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ABC_tran_CTD PF16326.5 EGF77134.1 - 0.33 11.2 7.2 0.25 11.6 5.2 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain APG6_N PF17675.1 EGF77134.1 - 0.4 11.2 13.0 0.99 9.9 13.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 EGF77134.1 - 0.49 10.9 14.7 1.8 9.1 5.4 2.9 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 EGF77134.1 - 0.61 10.7 7.9 2.5 8.8 7.1 2.4 1 1 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 EGF77134.1 - 1 9.4 14.5 0.1 12.6 6.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ABC_tran_Xtn PF12848.7 EGF77134.1 - 2.1 8.4 5.1 5.8 7.0 5.1 1.8 1 0 0 1 1 1 0 ABC transporter DUF4407 PF14362.6 EGF77134.1 - 4.7 6.5 6.9 7.9 5.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aminotran_3 PF00202.21 EGF77135.1 - 8.6e-120 400.1 0.0 1.1e-119 399.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGF77135.1 - 0.00032 20.0 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RNA_polI_A34 PF08208.11 EGF77136.1 - 3e-11 43.8 1.3 4.1e-11 43.4 1.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 polyprenyl_synt PF00348.17 EGF77137.1 - 6.9e-58 195.7 0.1 8.2e-58 195.5 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1456 PF07308.13 EGF77137.1 - 0.029 14.7 0.3 0.077 13.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) FTP PF07504.13 EGF77139.1 - 9.3e-13 47.8 0.2 2.4e-12 46.5 0.2 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M36 PF02128.15 EGF77140.1 - 5.8e-105 351.5 1.1 6.4e-105 351.3 1.1 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) MR_MLE_N PF02746.16 EGF77140.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain E1-E2_ATPase PF00122.20 EGF77142.1 - 1.6e-23 83.1 0.2 1.6e-23 83.1 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGF77142.1 - 1.2e-12 48.6 0.2 1.5e-06 28.6 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF77142.1 - 7.6e-05 22.3 0.0 0.00022 20.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGF77142.1 - 0.026 14.6 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) S6PP PF05116.13 EGF77142.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Peptidase_M36 PF02128.15 EGF77143.1 - 6.2e-74 249.4 0.6 7.2e-74 249.2 0.6 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 EGF77143.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase M50B-like MR_MLE_N PF02746.16 EGF77143.1 - 0.16 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Asp PF00026.23 EGF77144.1 - 2e-12 47.2 0.1 3.2e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77144.1 - 6.5e-08 32.5 0.1 6.5e-07 29.3 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF77144.1 - 0.11 13.0 0.0 24 5.6 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PGDH_C PF16896.5 EGF77145.1 - 0.19 11.7 0.3 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Phosphogluconate dehydrogenase (decarboxylating) C-term Fzo_mitofusin PF04799.13 EGF77145.1 - 0.3 10.6 1.8 1.1 8.8 0.9 2.2 1 1 1 2 2 2 0 fzo-like conserved region ADIP PF11559.8 EGF77145.1 - 0.75 9.9 5.2 1.5 8.9 5.2 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding IstB_IS21 PF01695.17 EGF77146.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NOC3p PF07540.11 EGF77147.1 - 0.17 12.3 0.2 0.17 12.3 0.2 1.7 2 1 0 2 2 2 0 Nucleolar complex-associated protein NOC3p PF07540.11 EGF77149.1 - 0.08 13.4 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein Sec2p PF06428.11 EGF77149.1 - 0.24 11.4 2.5 7.3 6.6 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF77149.1 - 0.8 9.9 4.9 1.5 9.0 0.3 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IstB_IS21 PF01695.17 EGF77150.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein WDCP PF15390.6 EGF77151.1 - 0.056 11.8 5.2 0.079 11.3 5.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family RecG_N PF17190.4 EGF77151.1 - 0.088 13.5 0.4 0.2 12.4 0.4 1.5 1 0 0 1 1 1 0 RecG N-terminal helical domain Dynactin_p22 PF07426.11 EGF77151.1 - 0.096 12.5 1.1 0.17 11.7 1.1 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 Histone_HNS PF00816.21 EGF77151.1 - 0.15 12.9 2.1 20 6.1 0.0 3.2 3 0 0 3 3 3 0 H-NS histone family LCIB_C_CA PF18599.1 EGF77152.1 - 0.48 9.7 1.8 0.92 8.8 0.0 1.9 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FAM176 PF14851.6 EGF77152.1 - 0.77 9.4 3.6 0.7 9.6 1.3 1.9 2 0 0 2 2 2 0 FAM176 family Pox_RNA_Pol_19 PF05320.12 EGF77152.1 - 4 7.4 12.1 3.1 7.7 8.8 2.4 2 1 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit AAA PF00004.29 EGF77153.1 - 5.9e-07 30.0 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF77153.1 - 0.0005 19.6 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGF77153.1 - 0.0048 17.4 0.0 0.0098 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF77153.1 - 0.0053 16.5 0.2 0.015 15.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF77153.1 - 0.0068 16.8 0.0 0.028 14.8 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGF77153.1 - 0.0099 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRTase_1 PF11202.8 EGF77153.1 - 0.01 15.1 0.0 0.031 13.5 0.0 1.8 3 0 0 3 3 3 0 Phosphoribosyl transferase (PRTase) RNA_helicase PF00910.22 EGF77153.1 - 0.031 14.7 0.2 0.18 12.2 0.0 2.3 1 1 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 EGF77153.1 - 0.057 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGF77153.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TK PF00265.18 EGF77153.1 - 0.062 13.2 0.0 0.16 11.8 0.0 1.7 1 1 1 2 2 2 0 Thymidine kinase AAA_5 PF07728.14 EGF77153.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGF77153.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ISP1_C PF18161.1 EGF77154.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 ISP1 C-terminal TPR_MLP1_2 PF07926.12 EGF77155.1 - 0.0022 18.0 2.0 0.0035 17.4 2.0 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein SH3BP5 PF05276.14 EGF77155.1 - 0.27 11.0 5.6 0.39 10.5 5.6 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DivIC PF04977.15 EGF77155.1 - 0.37 10.6 6.0 6.1 6.7 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator TMPIT PF07851.13 EGF77155.1 - 0.38 10.0 3.2 0.57 9.4 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 EGF77155.1 - 1.2 9.2 12.7 0.43 10.6 4.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MetOD2 PF18548.1 EGF77155.1 - 5.7 7.1 8.0 0.66 10.1 3.9 1.6 2 0 0 2 2 2 0 Metanogen output domain 2 Ndc1_Nup PF09531.10 EGF77156.1 - 0.56 8.8 12.7 0.69 8.5 12.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TP53IP5 PF15331.6 EGF77156.1 - 0.97 9.5 6.7 0.62 10.2 5.1 1.5 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Asp PF00026.23 EGF77157.1 - 1e-12 48.2 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77157.1 - 1.8e-05 24.5 0.1 0.0001 22.1 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF742 PF05331.11 EGF77157.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) ID PF18543.1 EGF77157.1 - 0.12 12.4 0.5 1 9.4 0.1 2.5 2 0 0 2 2 2 0 Intracellular delivery domain TAXi_C PF14541.6 EGF77158.1 - 6.3e-05 22.8 0.3 0.03 14.1 0.1 2.2 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp PF00026.23 EGF77158.1 - 0.0021 17.5 0.2 0.016 14.7 0.1 1.8 1 1 1 2 2 2 1 Eukaryotic aspartyl protease DUF2009 PF09418.10 EGF77159.1 - 1.3e-218 726.6 0.1 1.5e-218 726.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) APH PF01636.23 EGF77160.1 - 6.4e-05 23.0 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGF77160.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EGF77160.1 - 0.14 11.4 0.0 0.67 9.2 0.0 1.9 1 1 0 1 1 1 0 Ecdysteroid kinase Polysacc_deac_1 PF01522.21 EGF77161.1 - 7.5e-32 109.8 0.0 1.3e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase RNB PF00773.19 EGF77162.1 - 0.031 13.6 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 RNB domain DUF4106 PF13388.6 EGF77163.1 - 0.086 12.1 4.9 0.032 13.5 2.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) K-box PF01486.17 EGF77164.1 - 0.031 14.4 0.2 0.082 13.1 0.0 1.8 1 1 0 1 1 1 0 K-box region PAH PF02671.21 EGF77164.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Paired amphipathic helix repeat Com_YlbF PF06133.11 EGF77164.1 - 0.21 12.2 1.8 1.4 9.6 1.8 1.9 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA PRIMA1 PF16101.5 EGF77166.1 - 0.059 13.4 7.4 0.12 12.4 7.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGF77166.1 - 3.9 6.9 5.4 9.1 5.7 5.4 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC1 PF03109.16 EGF77167.1 - 4.7e-29 101.0 0.0 2.2e-28 98.8 0.0 2.0 1 1 1 2 2 2 1 ABC1 family RIO1 PF01163.22 EGF77167.1 - 8.2e-06 25.5 0.2 4.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGF77167.1 - 0.002 18.1 0.1 0.9 9.4 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.11 EGF77167.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 EGF77167.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EGF77168.1 - 3.6e-66 223.2 0.0 4.1e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77168.1 - 4.3e-49 167.1 0.0 5.2e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77168.1 - 8.9e-09 34.6 0.0 1.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF77168.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF77168.1 - 0.00035 19.6 0.0 0.00059 18.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGF77168.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.5 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EGF77168.1 - 0.032 14.2 0.0 0.093 12.6 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family KIND PF16474.5 EGF77168.1 - 0.056 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Ribosomal_L5_C PF00673.21 EGF77169.1 - 5.9e-18 64.8 0.0 9.5e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus SCA7 PF08313.12 EGF77170.1 - 0.075 12.9 0.1 0.075 12.9 0.1 1.9 2 0 0 2 2 2 0 SCA7, zinc-binding domain Toxin_24 PF08094.11 EGF77170.1 - 0.14 12.0 2.9 0.65 9.9 1.3 2.4 2 0 0 2 2 2 0 Conotoxin TVIIA/GS family EB PF01683.18 EGF77170.1 - 0.28 11.5 6.0 2.4 8.5 2.6 2.2 1 1 1 2 2 2 0 EB module CBM_1 PF00734.18 EGF77170.1 - 1.1 9.3 5.4 11 6.1 0.8 2.7 2 0 0 2 2 2 0 Fungal cellulose binding domain IGFBP PF00219.18 EGF77170.1 - 1.1 9.9 7.0 6.1 7.6 0.7 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein Toxin_7 PF05980.12 EGF77170.1 - 1.3 9.3 6.9 7.5 6.9 1.5 2.4 2 0 0 2 2 2 0 Toxin 7 DEC-1_N PF04625.13 EGF77170.1 - 8.1 5.3 8.0 13 4.6 8.0 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PIG-Y PF15159.6 EGF77171.1 - 0.019 15.9 1.0 0.036 15.0 1.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PAH PF02671.21 EGF77172.1 - 2.6e-12 46.7 2.7 2.3e-08 34.0 0.5 2.5 2 0 0 2 2 2 2 Paired amphipathic helix repeat CCM2_C PF16545.5 EGF77172.1 - 0.052 14.1 0.0 0.41 11.2 0.0 2.3 2 1 0 2 2 2 0 Cerebral cavernous malformation protein, harmonin-homology Secretin_N_2 PF07655.13 EGF77172.1 - 1.1 9.9 9.7 0.4 11.2 0.7 3.3 3 0 0 3 3 3 0 Secretin N-terminal domain DUF4460 PF14687.6 EGF77173.1 - 3.2e-12 46.5 0.3 1.1e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) RhoGAP PF00620.27 EGF77175.1 - 0.0026 17.6 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Sec66 PF09802.9 EGF77176.1 - 1.7e-23 83.2 5.1 4.3e-23 81.8 5.1 1.7 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF2220 PF09983.9 EGF77176.1 - 7.6 5.9 9.1 18 4.6 9.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) UBA PF00627.31 EGF77177.1 - 2.1e-10 40.3 1.4 5.6e-10 38.9 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 EGF77177.1 - 3.9e-07 29.7 0.1 8.3e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease PF09668.10 EGF77177.1 - 6e-06 26.1 0.7 0.0088 15.8 0.1 2.5 1 1 1 2 2 2 2 Aspartyl protease UBA_4 PF14555.6 EGF77177.1 - 0.002 17.9 0.1 0.0055 16.5 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain Rad60-SLD PF11976.8 EGF77177.1 - 0.0034 17.2 0.1 0.0067 16.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cytochrom_NNT PF03264.14 EGF77177.1 - 0.15 11.7 0.2 0.26 11.0 0.2 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region UcrQ PF02939.16 EGF77178.1 - 2.4e-22 78.6 0.4 2.8e-22 78.4 0.4 1.0 1 0 0 1 1 1 1 UcrQ family AAA PF00004.29 EGF77179.1 - 5.1e-43 146.7 0.0 1.6e-42 145.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF77179.1 - 3.8e-12 45.8 0.1 8.9e-12 44.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGF77179.1 - 4.9e-07 29.6 0.8 1.3e-06 28.2 0.8 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGF77179.1 - 1.8e-06 28.0 0.0 1.2e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF77179.1 - 3.8e-06 27.4 0.1 5.9e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EGF77179.1 - 4.9e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGF77179.1 - 9.8e-05 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF77179.1 - 0.00012 22.3 0.0 0.0084 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EGF77179.1 - 0.00066 20.2 0.1 0.022 15.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 EGF77179.1 - 0.001 18.4 0.0 0.0027 17.0 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGF77179.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGF77179.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGF77179.1 - 0.0064 16.4 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGF77179.1 - 0.0077 15.6 0.3 0.019 14.3 0.1 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGF77179.1 - 0.0097 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGF77179.1 - 0.014 14.8 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 EGF77179.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGF77179.1 - 0.019 14.3 0.1 0.053 12.9 0.0 1.8 1 1 0 1 1 1 0 KaiC DUF815 PF05673.13 EGF77179.1 - 0.023 13.9 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGF77179.1 - 0.027 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4618 PF15397.6 EGF77179.1 - 0.034 13.6 1.2 0.049 13.1 0.3 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4618) AAA_13 PF13166.6 EGF77179.1 - 0.034 12.8 0.0 1.5 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGF77179.1 - 0.035 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGF77179.1 - 0.037 14.4 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGF77179.1 - 0.038 13.7 0.0 0.07 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGF77179.1 - 0.051 12.8 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 EGF77179.1 - 0.052 13.6 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGF77179.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RILP PF11461.8 EGF77179.1 - 0.061 13.5 1.8 0.14 12.4 1.8 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein AAA_25 PF13481.6 EGF77179.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGF77179.1 - 0.072 12.9 0.1 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 EGF77179.1 - 0.078 13.2 1.9 0.14 12.4 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2072 PF09845.9 EGF77179.1 - 0.089 13.1 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein APG6_N PF17675.1 EGF77179.1 - 0.12 12.9 0.6 0.28 11.7 0.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_19 PF13245.6 EGF77179.1 - 0.12 12.7 0.7 0.64 10.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain PrmA PF06325.13 EGF77180.1 - 1.3e-10 41.2 4.0 1.6e-10 40.9 3.6 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGF77180.1 - 2.9e-10 40.7 0.4 1.2e-09 38.8 0.1 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF77180.1 - 1.8e-09 37.6 0.2 2.6e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF77180.1 - 8.6e-08 32.7 0.0 2.6e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF77180.1 - 3.7e-06 26.6 0.4 7e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGF77180.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGF77180.1 - 0.00021 21.2 0.1 0.00037 20.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF77180.1 - 0.00031 21.4 0.0 0.00075 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGF77180.1 - 0.0019 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EGF77180.1 - 0.0035 17.5 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 EGF77180.1 - 0.0043 16.5 1.1 0.012 15.0 0.3 2.0 2 1 0 2 2 2 1 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EGF77180.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EGF77180.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 EGF77180.1 - 0.078 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Profilin PF00235.19 EGF77181.1 - 3e-50 169.7 0.1 3.4e-50 169.6 0.1 1.0 1 0 0 1 1 1 1 Profilin Mo25 PF08569.11 EGF77182.1 - 1.8e-135 451.6 12.9 2e-135 451.4 12.9 1.0 1 0 0 1 1 1 1 Mo25-like Velvet PF11754.8 EGF77183.1 - 1.2e-39 136.8 1.6 2.2e-26 93.4 0.0 3.0 2 1 1 3 3 3 2 Velvet factor Citrate_synt PF00285.21 EGF77185.1 - 4.5e-137 456.9 0.0 5.8e-137 456.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain TFIIS_M PF07500.14 EGF77186.1 - 3.4e-15 56.5 0.2 7e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EGF77186.1 - 1.9e-14 53.8 0.0 3.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 SPOC domain MutS_V PF00488.21 EGF77187.1 - 4.2e-46 157.4 0.3 6e-45 153.6 0.3 2.4 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGF77187.1 - 3.1e-23 83.0 2.3 5.7e-23 82.1 1.0 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGF77187.1 - 0.0018 18.6 0.1 0.0045 17.3 0.0 1.8 2 0 0 2 2 2 1 MutS family domain IV DUF4828 PF16110.5 EGF77187.1 - 0.022 15.2 0.2 2.4 8.7 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4828) AAA_29 PF13555.6 EGF77187.1 - 0.17 11.6 0.2 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTP_transferase PF00483.23 EGF77188.1 - 3.6e-53 180.7 0.0 4.5e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGF77188.1 - 1.2e-11 43.9 6.6 2.7e-09 36.4 1.9 3.3 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGF77188.1 - 3.1e-10 40.6 0.0 3.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGF77188.1 - 2e-06 27.4 5.4 2.2e-06 27.3 1.7 2.8 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF257 PF03192.13 EGF77188.1 - 0.045 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 DUF4954 PF16314.5 EGF77188.1 - 0.11 10.6 0.1 0.16 10.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EGF77188.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.12 EGF77188.1 - 0.14 11.0 0.1 1.4 7.8 0.1 2.4 2 1 0 2 2 2 0 L-fucokinase IspD PF01128.19 EGF77188.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NIF PF03031.18 EGF77189.1 - 5e-54 182.3 0.2 5.8e-54 182.1 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Noc2 PF03715.13 EGF77189.1 - 0.0017 17.7 0.0 0.0021 17.4 0.0 1.0 1 0 0 1 1 1 1 Noc2p family DUF705 PF05152.12 EGF77189.1 - 0.0037 16.8 0.3 0.0047 16.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) OrfB_Zn_ribbon PF07282.11 EGF77191.1 - 0.28 11.1 1.8 1.8 8.5 1.4 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain WD40 PF00400.32 EGF77192.1 - 2.2e-05 25.1 22.5 0.00046 21.0 1.3 6.1 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EGF77192.1 - 0.015 15.8 0.2 4.1 8.0 0.0 3.6 3 1 1 4 4 4 0 PQQ-like domain TB2_DP1_HVA22 PF03134.19 EGF77194.1 - 1.5e-18 66.5 0.8 2.5e-18 65.8 0.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SH3_9 PF14604.6 EGF77195.1 - 1.9e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain WSC PF01822.19 EGF77195.1 - 0.00016 21.8 5.9 0.00025 21.2 5.9 1.3 1 0 0 1 1 1 1 WSC domain Adeno_E3_CR2 PF02439.15 EGF77195.1 - 0.00028 20.6 3.9 0.00048 19.8 3.9 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SH3_1 PF00018.28 EGF77195.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Glycophorin_A PF01102.18 EGF77195.1 - 0.02 15.1 0.2 0.038 14.2 0.2 1.4 1 0 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 EGF77195.1 - 0.039 13.9 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 EGF77195.1 - 0.049 13.6 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin RIFIN PF02009.16 EGF77195.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 EGF77195.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 EGF77195.1 - 0.15 13.0 0.1 0.31 12.0 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 EGF77195.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) BatA PF07584.11 EGF77195.1 - 0.76 10.2 6.2 0.45 10.9 0.2 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Syndecan PF01034.20 EGF77195.1 - 2.4 8.1 4.7 3.1 7.8 1.9 2.1 2 0 0 2 2 2 0 Syndecan domain Exo_endo_phos PF03372.23 EGF77197.1 - 2.2e-19 69.9 0.0 3.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 EGF77198.1 - 4.5e-38 130.7 0.0 7.5e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF77198.1 - 8e-11 41.6 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EGF77198.1 - 4.2e-06 26.8 0.0 8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGF77198.1 - 7.6e-06 25.8 0.0 2e-05 24.4 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGF77198.1 - 7.7e-06 26.4 0.3 0.00054 20.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGF77198.1 - 9.6e-06 26.2 0.0 2.4e-05 24.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EGF77198.1 - 4.3e-05 23.8 0.5 0.0027 18.0 0.3 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF77198.1 - 4.8e-05 23.5 0.0 7.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGF77198.1 - 6.7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGF77198.1 - 8.7e-05 22.5 0.2 0.00081 19.4 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGF77198.1 - 0.00044 20.6 0.0 0.0024 18.3 0.0 2.2 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 EGF77198.1 - 0.00051 19.5 0.1 2.3 7.6 0.0 3.1 2 1 1 3 3 3 2 Bacterial TniB protein Mg_chelatase PF01078.21 EGF77198.1 - 0.00085 18.8 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EGF77198.1 - 0.0009 19.2 0.0 0.003 17.5 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EGF77198.1 - 0.0017 18.0 0.1 0.12 11.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGF77198.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 EGF77198.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF77198.1 - 0.0032 17.2 0.0 0.006 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 EGF77198.1 - 0.0054 16.6 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.12 EGF77198.1 - 0.0073 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGF77198.1 - 0.0078 16.2 0.1 0.092 12.6 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea ATPase PF06745.13 EGF77198.1 - 0.0084 15.5 0.2 1.8 7.8 0.0 2.7 1 1 1 2 2 2 1 KaiC DUF815 PF05673.13 EGF77198.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 EGF77198.1 - 0.0088 15.7 0.0 0.75 9.5 0.0 3.0 3 0 0 3 3 3 1 Guanylate kinase TIP49 PF06068.13 EGF77198.1 - 0.01 15.1 0.1 0.035 13.3 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain ABC_tran PF00005.27 EGF77198.1 - 0.011 16.2 0.0 0.051 14.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 EGF77198.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EGF77198.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EGF77198.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CPT PF07931.12 EGF77198.1 - 0.016 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EGF77198.1 - 0.03 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EGF77198.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EGF77198.1 - 0.069 13.6 0.3 0.27 11.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGF77198.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGF77198.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 EGF77198.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_21 PF13304.6 EGF77198.1 - 0.089 12.6 0.1 5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system COesterase PF00135.28 EGF77199.1 - 8.3e-94 315.3 0.0 1.3e-92 311.3 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGF77199.1 - 6.1e-05 23.0 0.1 0.00029 20.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-AN1 PF01428.16 EGF77200.1 - 4.8e-20 71.4 26.3 1.1e-10 41.5 6.4 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger DUF4428 PF14471.6 EGF77200.1 - 0.5 10.3 9.2 3.1 7.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) A2L_zn_ribbon PF08792.10 EGF77200.1 - 0.64 9.8 0.1 0.64 9.8 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Pkinase PF00069.25 EGF77201.1 - 5.7e-74 248.8 0.0 7.8e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77201.1 - 1.7e-45 155.3 0.0 2.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77201.1 - 7.1e-09 35.4 0.0 4.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGF77201.1 - 0.0034 16.9 0.1 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 EGF77201.1 - 0.0055 16.3 0.2 0.039 13.5 0.0 2.3 2 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EGF77201.1 - 0.0081 15.0 0.1 0.012 14.4 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGF77201.1 - 0.0091 15.6 0.1 0.095 12.3 0.0 2.2 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGF77201.1 - 0.01 15.2 0.2 0.023 14.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF77201.1 - 0.091 12.7 0.4 0.65 9.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kelch_5 PF13854.6 EGF77202.1 - 2.5e-26 91.2 0.2 2e-05 24.4 0.0 5.5 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EGF77202.1 - 1.7e-23 82.4 2.8 1e-07 31.8 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF77202.1 - 1.4e-22 79.1 2.1 4.7e-06 26.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 EGF77202.1 - 4.4e-17 61.4 4.1 3.8e-05 23.2 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EGF77202.1 - 1.3e-16 60.4 9.0 0.00056 20.1 0.0 5.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGF77202.1 - 4.4e-15 55.0 6.2 0.00098 19.0 0.0 5.8 5 1 0 5 5 5 3 Kelch motif DNA_pol3_chi PF04364.13 EGF77202.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC ADH_zinc_N PF00107.26 EGF77203.1 - 2.9e-28 98.5 0.2 4.7e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGF77203.1 - 3.2e-20 73.5 0.0 7.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGF77203.1 - 1.7e-05 24.6 0.0 3.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NMO PF03060.15 EGF77203.1 - 0.0039 16.6 0.1 0.0058 16.1 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DUF2855 PF11017.8 EGF77203.1 - 0.055 13.2 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) PA PF02225.22 EGF77203.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 PA domain ADH_N_2 PF16884.5 EGF77203.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PWI PF01480.17 EGF77204.1 - 4.7e-09 36.4 2.3 8.3e-09 35.6 0.9 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 EGF77204.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 EGF77205.1 - 1.6e-09 37.7 19.9 0.0018 18.7 0.3 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF77205.1 - 4.7e-06 26.8 14.5 2.4e-05 24.5 0.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF77205.1 - 4.5e-05 23.9 22.3 0.0016 19.1 0.3 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF77205.1 - 0.00018 21.7 3.3 0.29 11.5 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGF77205.1 - 0.00032 20.6 9.6 0.012 15.6 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGF77205.1 - 0.0084 16.0 0.5 0.0084 16.0 0.5 2.0 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 EGF77205.1 - 0.042 14.2 2.1 3.3 8.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGF77205.1 - 0.06 13.7 3.1 1.9 8.9 0.0 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 EGF77205.1 - 0.6 9.9 13.2 0.61 9.9 1.7 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HECT PF00632.25 EGF77206.1 - 3.4e-95 319.1 0.0 4.5e-95 318.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EGF77206.1 - 5.6e-34 115.9 15.6 1e-11 44.7 0.7 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EGF77206.1 - 7.2e-20 71.2 0.3 2.4e-18 66.3 0.2 2.5 1 1 1 2 2 2 1 C2 domain ParBc_2 PF08857.11 EGF77206.1 - 0.033 14.3 0.1 0.7 10.0 0.0 2.9 3 1 0 3 3 3 0 Putative ParB-like nuclease Mito_carr PF00153.27 EGF77207.1 - 1.5e-14 53.6 6.3 3.6e-07 30.0 0.5 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EGF77207.1 - 0.17 12.3 7.0 0.37 11.2 0.2 2.8 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RsbU_N PF08673.10 EGF77207.1 - 0.2 11.7 0.4 0.45 10.6 0.4 1.5 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Pkinase PF00069.25 EGF77208.1 - 5.1e-42 144.1 0.6 8.1e-28 97.5 0.1 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77208.1 - 6.3e-25 87.9 0.1 2.9e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF77208.1 - 2.4e-07 30.1 0.1 2.4e-07 30.1 0.1 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGF77208.1 - 0.00017 21.0 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGF77208.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF77208.1 - 0.01 14.6 0.8 0.01 14.6 0.8 1.4 1 1 0 1 1 1 0 Fungal protein kinase DUF4854 PF16146.5 EGF77208.1 - 0.056 13.8 0.1 0.14 12.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) APH PF01636.23 EGF77208.1 - 0.073 13.0 0.9 0.22 11.4 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family ISN1 PF06437.11 EGF77209.1 - 1.5e-116 389.7 0.0 1.9e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Arrestin_N PF00339.29 EGF77210.1 - 1.3e-19 70.7 0.0 2.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGF77210.1 - 3.1e-10 40.6 0.1 1.2e-07 32.3 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 EGF77210.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like AAA PF00004.29 EGF77211.1 - 5.6e-55 185.4 0.0 7e-39 133.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF77211.1 - 8.6e-10 38.3 0.4 3.5e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 EGF77211.1 - 1.2e-09 38.6 0.0 0.00085 19.6 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EGF77211.1 - 9.7e-09 35.6 0.0 1.6e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGF77211.1 - 1.5e-08 35.2 0.0 0.01 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EGF77211.1 - 2.1e-07 30.8 0.2 0.022 14.5 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGF77211.1 - 2.5e-07 30.2 0.1 0.0069 15.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 EGF77211.1 - 2.5e-07 30.8 0.0 0.00058 19.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGF77211.1 - 1.3e-06 28.2 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 EGF77211.1 - 1.5e-06 28.1 0.1 0.0018 18.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 EGF77211.1 - 6.4e-06 26.2 0.1 0.1 12.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGF77211.1 - 6.9e-06 26.4 0.0 0.06 13.7 0.0 3.3 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.21 EGF77211.1 - 1.3e-05 24.7 0.4 0.0086 15.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGF77211.1 - 3.1e-05 24.2 0.1 0.18 11.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 EGF77211.1 - 4.1e-05 24.1 0.0 0.012 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGF77211.1 - 5.3e-05 23.0 0.0 0.41 10.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EGF77211.1 - 7e-05 22.8 0.4 14 5.5 0.0 4.2 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGF77211.1 - 7.3e-05 22.7 1.1 0.28 11.1 0.1 3.7 4 0 0 4 4 4 1 NACHT domain AAA_7 PF12775.7 EGF77211.1 - 0.00014 21.4 0.2 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ResIII PF04851.15 EGF77211.1 - 0.00043 20.3 0.0 0.9 9.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EGF77211.1 - 0.00047 19.4 0.3 0.65 9.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.16 EGF77211.1 - 0.00052 19.5 0.1 0.66 9.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 EGF77211.1 - 0.00082 19.0 2.1 1.8 8.1 0.0 3.5 2 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EGF77211.1 - 0.00092 19.7 0.2 1.7 9.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 EGF77211.1 - 0.0013 18.5 0.0 1.2 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EGF77211.1 - 0.0072 15.6 0.0 0.39 10.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin CDC48_2 PF02933.17 EGF77211.1 - 0.0072 16.1 0.4 0.14 11.9 0.0 2.8 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 CDC48_N PF02359.18 EGF77211.1 - 0.0082 16.3 0.0 0.074 13.2 0.0 2.6 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain DUF2075 PF09848.9 EGF77211.1 - 0.0094 15.2 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EGF77211.1 - 0.011 15.1 0.0 0.52 9.6 0.0 2.7 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 EGF77211.1 - 0.012 14.8 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EGF77211.1 - 0.012 15.9 0.0 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGF77211.1 - 0.014 14.5 0.1 1.6 7.7 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 EGF77211.1 - 0.015 15.1 0.0 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EGF77211.1 - 0.019 14.2 0.4 3.8 6.6 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 IPT PF01745.16 EGF77211.1 - 0.022 14.2 0.1 0.57 9.5 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DEAD PF00270.29 EGF77211.1 - 0.028 14.2 1.3 5.6 6.7 0.2 3.6 2 2 1 4 4 4 0 DEAD/DEAH box helicase AAA_3 PF07726.11 EGF77211.1 - 0.036 13.9 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EGF77211.1 - 0.041 14.0 0.1 13 5.9 0.0 3.2 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGF77211.1 - 0.05 13.9 0.3 1.5 9.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGF77211.1 - 0.29 11.6 0.8 1.3 9.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain Acyl-CoA_dh_1 PF00441.24 EGF77212.1 - 4e-36 124.5 0.3 7.5e-36 123.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF77212.1 - 1.7e-19 69.8 0.1 2.9e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EGF77212.1 - 8.6e-19 67.5 0.0 2.4e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGF77212.1 - 4.1e-14 53.2 0.0 1.1e-13 51.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF77212.1 - 4.2e-06 27.1 0.0 7.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fimbrial_K88 PF02432.15 EGF77212.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit SPICE PF15678.5 EGF77212.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression SET PF00856.28 EGF77213.1 - 7.7e-14 52.4 0.8 7.7e-14 52.4 0.8 3.8 3 2 0 3 3 3 1 SET domain Cupin_8 PF13621.6 EGF77214.1 - 2.6e-37 128.9 0.0 4.4e-37 128.2 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGF77214.1 - 0.024 15.0 0.0 0.08 13.4 0.0 1.9 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGF77214.1 - 0.048 13.1 0.4 2.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Cupin superfamily protein CK2S PF15011.6 EGF77215.1 - 7.4e-08 32.4 1.6 0.0014 18.5 0.1 2.7 2 1 0 2 2 2 2 Casein Kinase 2 substrate FAA_hydro_N_2 PF18288.1 EGF77215.1 - 0.03 14.8 0.2 6.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 TPT PF03151.16 EGF77216.1 - 6.7e-38 130.7 21.4 8.8e-38 130.3 21.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family ArfGap PF01412.18 EGF77216.1 - 2.1e-27 95.5 0.1 2.1e-27 95.5 0.1 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UAA PF08449.11 EGF77216.1 - 2.2e-10 40.2 23.1 2.9e-10 39.8 23.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGF77216.1 - 3.2e-07 30.6 34.0 0.00079 19.6 12.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family EF-hand_1 PF00036.32 EGF77217.1 - 3.9e-20 69.8 7.0 5.5e-05 22.4 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGF77217.1 - 2.5e-19 67.5 7.6 9.2e-05 22.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGF77217.1 - 2.2e-14 53.7 4.8 2.1e-08 34.5 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGF77217.1 - 1.8e-12 46.2 2.8 0.0028 17.1 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGF77217.1 - 8.8e-08 31.9 5.8 0.00049 19.9 0.5 3.9 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGF77217.1 - 0.0019 18.5 2.3 0.039 14.3 0.1 2.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGF77217.1 - 0.0036 17.2 3.2 0.072 13.1 0.4 2.8 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Acetyltransf_11 PF13720.6 EGF77217.1 - 0.055 13.9 0.1 6.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_9 PF14658.6 EGF77217.1 - 0.074 13.4 0.1 2 8.8 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Ferrochelatase PF00762.19 EGF77218.1 - 6.2e-112 373.8 0.0 7.2e-112 373.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EGF77218.1 - 0.0043 17.3 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 CbiX SPRY PF00622.28 EGF77219.1 - 9e-17 61.3 0.7 1.7e-16 60.4 0.7 1.5 1 0 0 1 1 1 1 SPRY domain Arm PF00514.23 EGF77219.1 - 2e-05 24.4 3.2 0.25 11.4 0.0 6.3 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGF77219.1 - 0.062 12.8 12.0 0.045 13.2 5.3 3.1 2 1 1 3 3 3 0 Armadillo-like SIL1 PF16782.5 EGF77219.1 - 0.69 9.1 3.0 0.6 9.3 0.6 2.0 1 1 1 2 2 2 0 Nucleotide exchange factor SIL1 Cpn60_TCP1 PF00118.24 EGF77220.1 - 1.7e-145 485.4 10.3 2e-145 485.2 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EGF77220.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF4246 PF14033.6 EGF77221.1 - 1.6e-29 103.3 0.0 2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) SKA2 PF16740.5 EGF77222.1 - 0.00027 20.7 2.4 0.023 14.5 2.0 2.5 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 Uso1_p115_C PF04871.13 EGF77222.1 - 0.0012 19.2 6.0 0.0012 19.2 6.0 1.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region PIN_8 PF18476.1 EGF77222.1 - 0.0031 17.4 1.3 0.004 17.0 1.3 1.2 1 0 0 1 1 1 1 PIN like domain PI3K_P85_iSH2 PF16454.5 EGF77222.1 - 0.0035 16.9 4.5 0.037 13.6 0.0 2.1 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMPIT PF07851.13 EGF77222.1 - 0.006 15.9 0.4 0.0077 15.5 0.4 1.1 1 0 0 1 1 1 1 TMPIT-like protein Laminin_II PF06009.12 EGF77222.1 - 0.012 15.6 1.3 0.018 15.1 1.3 1.3 1 0 0 1 1 1 0 Laminin Domain II FH2 PF02181.23 EGF77222.1 - 0.021 14.0 2.6 0.028 13.6 2.6 1.2 1 1 0 1 1 1 0 Formin Homology 2 Domain MAD PF05557.13 EGF77222.1 - 0.023 13.1 5.1 0.028 12.8 5.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Ribosomal_S2 PF00318.20 EGF77222.1 - 0.023 14.0 0.2 0.029 13.6 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 IFT57 PF10498.9 EGF77222.1 - 0.023 13.7 2.9 0.031 13.2 2.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF5082 PF16888.5 EGF77222.1 - 0.057 13.7 8.2 0.84 9.9 6.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4709 PF15821.5 EGF77222.1 - 0.067 13.5 2.1 9.2 6.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) LPP PF04728.13 EGF77222.1 - 0.068 13.6 2.0 26 5.3 0.0 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Rb_C PF08934.10 EGF77222.1 - 0.074 12.8 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Rb C-terminal domain Tektin PF03148.14 EGF77222.1 - 0.076 11.8 7.0 0.19 10.4 3.2 2.0 1 1 1 2 2 2 0 Tektin family WXG100 PF06013.12 EGF77222.1 - 0.093 13.0 0.1 0.17 12.1 0.1 1.5 1 1 0 1 1 1 0 Proteins of 100 residues with WXG GNAT_acetyltr_2 PF13718.6 EGF77222.1 - 0.093 12.1 0.3 0.13 11.6 0.3 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Fib_alpha PF08702.10 EGF77222.1 - 0.14 12.3 2.6 4.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EGF77222.1 - 0.3 11.5 5.7 40 4.7 4.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EGF77222.1 - 0.4 10.7 3.4 1.9 8.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EGF77222.1 - 0.49 10.9 9.8 2.1 8.8 2.9 2.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF4200 PF13863.6 EGF77222.1 - 0.6 10.5 9.3 0.44 11.0 3.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Swi5 PF07061.11 EGF77222.1 - 0.98 9.6 7.6 1.8 8.7 3.0 3.0 2 1 2 4 4 4 0 Swi5 Seryl_tRNA_N PF02403.22 EGF77222.1 - 1.5 9.1 8.4 12 6.2 7.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MYO10_CC PF16735.5 EGF77222.1 - 2 8.6 12.9 4.6 7.4 2.7 2.4 1 1 1 2 2 2 0 Unconventional myosin-X coiled coil domain DivIC PF04977.15 EGF77222.1 - 4.9 7.0 8.0 6.2 6.7 2.5 2.9 2 1 1 3 3 3 0 Septum formation initiator TFIID_20kDa PF03847.13 EGF77223.1 - 3.5e-23 81.9 3.3 6e-23 81.1 3.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EGF77223.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGF77223.1 - 0.016 15.3 0.8 0.024 14.7 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit AAA PF00004.29 EGF77225.1 - 2.4e-95 316.0 0.0 1e-46 158.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF77225.1 - 2.6e-24 84.8 4.3 2.4e-12 46.4 0.4 3.1 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 EGF77225.1 - 1.9e-16 60.0 0.4 4.7e-16 58.7 0.4 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGF77225.1 - 1.3e-13 51.0 0.0 2.4e-05 24.1 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGF77225.1 - 2.5e-12 47.2 0.0 5.4e-07 29.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGF77225.1 - 1.5e-11 44.7 0.0 6.8e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGF77225.1 - 6.9e-11 42.8 0.2 0.0024 18.3 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 EGF77225.1 - 1.2e-10 41.5 0.1 3.9e-05 23.7 0.1 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 EGF77225.1 - 4.4e-09 36.0 0.0 9.3e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EGF77225.1 - 5.3e-09 36.5 0.1 0.026 14.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGF77225.1 - 1.8e-08 34.0 0.1 0.002 17.4 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 EGF77225.1 - 1.6e-07 31.2 0.1 2.6e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 EGF77225.1 - 3.2e-07 29.9 0.2 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGF77225.1 - 3.9e-07 30.7 0.0 0.036 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGF77225.1 - 7.7e-07 29.5 0.0 0.0059 17.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGF77225.1 - 1.3e-06 28.5 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EGF77225.1 - 1.4e-06 28.9 0.0 0.0076 16.8 0.0 3.5 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 EGF77225.1 - 2.3e-06 27.5 0.0 0.062 13.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 EGF77225.1 - 6e-06 26.0 0.9 1.4 8.4 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_17 PF13207.6 EGF77225.1 - 6.8e-06 26.5 0.2 0.43 11.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EGF77225.1 - 9.2e-06 26.0 0.0 0.17 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EGF77225.1 - 1.4e-05 24.7 0.0 0.064 12.8 0.0 3.0 3 1 0 3 3 2 2 P-loop containing dynein motor region ATPase PF06745.13 EGF77225.1 - 7.6e-05 22.2 0.2 2.2 7.6 0.0 3.5 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.18 EGF77225.1 - 8.8e-05 22.4 0.0 0.0074 16.1 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EGF77225.1 - 8.9e-05 22.2 0.0 0.59 9.8 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EGF77225.1 - 0.0001 21.5 0.1 0.033 13.3 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 EGF77225.1 - 0.00013 21.2 0.0 0.029 13.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EGF77225.1 - 0.00014 21.8 0.0 0.68 9.7 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 EGF77225.1 - 0.00024 20.9 0.0 0.71 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EGF77225.1 - 0.00028 20.9 0.1 0.26 11.2 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGF77225.1 - 0.00032 20.0 0.0 0.53 9.5 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 EGF77225.1 - 0.00046 20.2 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EGF77225.1 - 0.00072 19.1 0.2 1.3 8.4 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 EGF77225.1 - 0.00088 19.1 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGF77225.1 - 0.001 19.1 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EGF77225.1 - 0.0015 17.8 0.0 0.18 11.0 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.6 EGF77225.1 - 0.0023 18.1 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 EGF77225.1 - 0.0024 17.7 0.5 1.7 8.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EGF77225.1 - 0.0027 17.6 0.2 0.3 11.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain DUF2075 PF09848.9 EGF77225.1 - 0.0029 16.9 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 EGF77225.1 - 0.0043 17.0 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 EGF77225.1 - 0.017 15.5 2.1 7.7 6.8 0.2 3.3 3 1 1 4 4 2 0 AAA domain Cytidylate_kin2 PF13189.6 EGF77225.1 - 0.019 15.1 0.1 1.6 8.8 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase-like family SRPRB PF09439.10 EGF77225.1 - 0.024 14.1 0.4 27 4.1 0.2 3.9 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 EGF77225.1 - 0.032 14.1 0.4 5.6 6.9 0.0 3.5 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 EGF77225.1 - 0.04 13.6 0.1 7.1 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGF77225.1 - 0.04 13.6 0.0 8.7 6.0 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 EGF77225.1 - 0.057 13.5 0.1 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 EGF77225.1 - 0.15 11.8 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M36 PF02128.15 EGF77226.1 - 3.3e-81 273.3 0.2 3.7e-81 273.2 0.2 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 EGF77226.1 - 0.1 12.2 0.2 0.1 12.2 0.2 1.5 2 0 0 2 2 2 0 Peptidase M50B-like MR_MLE_N PF02746.16 EGF77226.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain APG6_N PF17675.1 EGF77228.1 - 2.1e-06 28.3 22.7 7.7e-05 23.2 5.7 2.3 2 0 0 2 2 2 2 Apg6 coiled-coil region V_ATPase_I PF01496.19 EGF77228.1 - 0.0049 14.9 15.1 0.0083 14.1 4.3 2.1 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF4062 PF13271.6 EGF77228.1 - 0.03 14.7 0.6 22 5.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) PEP-utilisers_N PF05524.13 EGF77228.1 - 0.054 13.7 14.0 1.2 9.3 0.1 3.3 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal Flg_hook PF02120.16 EGF77228.1 - 0.31 11.0 0.1 0.31 11.0 0.1 3.0 3 1 0 3 3 3 0 Flagellar hook-length control protein FliK COG2 PF06148.11 EGF77228.1 - 0.6 10.2 9.2 1.1 9.3 0.9 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RMI1_C PF16099.5 EGF77228.1 - 1.1 9.1 10.5 0.62 9.9 1.0 3.2 3 0 0 3 3 3 0 Recq-mediated genome instability protein 1, C-terminal OB-fold JIP_LZII PF16471.5 EGF77228.1 - 1.2 9.4 15.8 1.9 8.7 0.3 4.1 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II IL10 PF00726.17 EGF77228.1 - 1.4 8.4 5.2 6.2 6.3 0.2 3.4 2 2 3 5 5 5 0 Interleukin 10 TarH PF02203.15 EGF77228.1 - 1.6 8.7 15.0 4.5 7.1 5.7 3.2 2 1 1 3 3 3 0 Tar ligand binding domain homologue BBS1 PF14779.6 EGF77228.1 - 1.6 8.1 5.8 0.16 11.4 0.4 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 SLATT_4 PF18186.1 EGF77228.1 - 3.9 7.1 8.2 5.1 6.7 0.3 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 Prominin PF05478.11 EGF77228.1 - 4.3 5.2 5.8 3 5.7 0.7 2.0 2 0 0 2 2 2 0 Prominin YabA PF06156.13 EGF77228.1 - 7.1 7.3 20.8 0.33 11.6 2.9 3.7 1 1 2 3 3 3 0 Initiation control protein YabA YtxH PF12732.7 EGF77228.1 - 9.1 6.9 17.9 0.89 10.1 4.0 3.4 2 1 0 2 2 2 0 YtxH-like protein Cofac_haem_bdg PF04187.13 EGF77229.1 - 0.0057 16.7 2.1 0.032 14.2 0.1 2.3 1 1 1 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN Spem1 PF15670.5 EGF77229.1 - 0.024 14.2 7.4 0.048 13.2 0.5 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 Inhibitor_I71 PF12628.7 EGF77229.1 - 0.091 12.6 5.5 0.18 11.7 0.8 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Lir1 PF07207.11 EGF77229.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.2 2 0 0 2 2 2 0 Light regulated protein Lir1 4HB_MCP_1 PF12729.7 EGF77229.1 - 0.35 10.4 6.5 0.54 9.8 4.8 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction kleA_kleC PF17383.2 EGF77229.1 - 1 9.8 3.0 0.5 10.7 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A APG6_N PF17675.1 EGF77229.1 - 1.8 9.1 13.0 6.9 7.2 9.9 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 EGF77229.1 - 2.7 7.2 7.0 2 7.6 5.3 1.5 2 0 0 2 2 2 0 TMPIT-like protein Peptidase_M36 PF02128.15 EGF77230.1 - 7.5e-137 456.4 0.5 8.5e-137 456.2 0.5 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 EGF77230.1 - 0.1 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like DUF1539 PF07560.11 EGF77231.1 - 0.018 15.1 7.5 13 5.9 4.5 3.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) Rgp1 PF08737.10 EGF77231.1 - 0.88 8.7 8.8 1.7 7.7 8.8 1.5 1 1 0 1 1 1 0 Rgp1 Glyco_trans_2_3 PF13632.6 EGF77232.1 - 5.3e-23 82.0 2.3 5.3e-23 82.0 2.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF77232.1 - 3.7e-14 53.2 0.0 5.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF77232.1 - 0.068 12.6 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 Herpes_glycop PF01528.16 EGF77232.1 - 0.33 9.8 3.5 0.55 9.0 3.5 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Syndecan PF01034.20 EGF77234.1 - 3.6 7.6 6.6 12 5.9 0.1 2.8 2 0 0 2 2 2 0 Syndecan domain HisKA_7TM PF16927.5 EGF77235.1 - 0.0049 16.9 19.6 0.0071 16.4 19.6 1.2 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase TIP120 PF08623.10 EGF77236.1 - 1.4e-49 168.1 8.2 5.6e-49 166.2 0.4 4.6 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EGF77236.1 - 2.2e-15 55.4 6.7 4.4 7.8 0.1 11.1 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 EGF77236.1 - 5.4e-14 52.4 1.7 1.6 9.1 0.1 9.0 8 2 1 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 EGF77236.1 - 5.6e-10 39.5 6.8 7.7 7.1 0.1 10.2 11 1 1 12 12 11 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGF77236.1 - 7.6e-10 39.3 2.1 0.075 13.6 0.0 6.5 8 0 0 8 8 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EGF77236.1 - 2.4e-08 33.5 23.5 0.0013 18.0 0.0 7.8 6 2 2 9 9 9 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 EGF77236.1 - 1.2e-06 27.4 22.8 0.0068 15.0 0.7 6.2 5 2 0 6 6 6 4 Adaptin N terminal region TAF6_C PF07571.13 EGF77236.1 - 7.5e-06 26.2 2.5 0.054 13.8 0.0 5.6 4 2 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 EGF77236.1 - 0.00049 20.2 15.4 3.4 7.7 0.0 6.5 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 EGF77236.1 - 0.05 13.3 5.7 19 4.9 0.0 5.9 6 2 0 6 6 6 0 Domain of unknown function (DUF4042) RRN3 PF05327.11 EGF77236.1 - 0.051 12.1 12.0 0.049 12.2 4.4 3.1 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 V-ATPase_H_C PF11698.8 EGF77236.1 - 0.068 13.3 0.4 26 4.9 0.0 4.5 4 0 0 4 4 4 0 V-ATPase subunit H Arg_decarbox_C PF17944.1 EGF77236.1 - 0.11 13.1 1.6 9.1 6.9 0.0 3.5 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension FAM176 PF14851.6 EGF77236.1 - 1.2 8.8 3.5 2.7 7.7 3.5 1.5 1 0 0 1 1 1 0 FAM176 family TAN PF11640.8 EGF77236.1 - 4 7.6 7.3 83 3.3 0.0 4.8 4 2 0 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF2457 PF10446.9 EGF77236.1 - 5.2 6.1 13.8 8 5.5 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kinesin PF00225.23 EGF77237.1 - 1.3e-99 333.3 2.7 1.3e-99 333.3 2.7 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGF77237.1 - 1.7e-25 89.7 0.0 7.2e-25 87.7 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 EGF77237.1 - 0.0014 18.4 0.1 0.29 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arg_decarbox_C PF17944.1 EGF77237.1 - 0.058 14.0 5.5 0.51 10.9 0.1 3.5 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Flu_NS2 PF00601.19 EGF77237.1 - 0.15 12.4 1.5 0.56 10.5 1.5 2.1 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) AIP3 PF03915.13 EGF77237.1 - 0.5 9.4 17.2 0.12 11.4 2.6 2.7 2 1 0 3 3 3 0 Actin interacting protein 3 zf-C4H2 PF10146.9 EGF77237.1 - 0.62 10.3 10.3 0.67 10.2 5.0 2.7 2 0 0 2 2 2 0 Zinc finger-containing protein Med9 PF07544.13 EGF77237.1 - 5.2 7.2 7.5 1.2 9.3 3.4 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ebp2 PF05890.12 EGF77238.1 - 2.6e-66 223.9 24.2 2.6e-66 223.9 24.2 2.5 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Sclerostin PF05463.11 EGF77240.1 - 0.027 14.2 0.0 1.2 8.8 0.0 2.1 1 1 0 2 2 2 0 Sclerostin (SOST) Ank_2 PF12796.7 EGF77241.1 - 1e-14 54.9 0.3 7.4e-05 23.3 0.0 4.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF77241.1 - 8e-08 32.7 5.3 0.019 15.6 0.0 6.2 4 3 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF77241.1 - 1.2e-06 28.3 2.2 7.5 7.5 0.0 7.6 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 EGF77241.1 - 0.0031 17.8 4.0 41 4.6 0.1 5.8 6 1 1 7 7 7 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGF77241.1 - 0.0046 16.9 0.1 0.9 9.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ank PF00023.30 EGF77241.1 - 0.085 13.3 2.9 85 3.8 0.1 5.0 2 2 2 4 4 4 0 Ankyrin repeat DUF5316 PF17247.2 EGF77242.1 - 0.37 10.8 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5316) DUF599 PF04654.12 EGF77243.1 - 1e-54 185.2 14.0 1.2e-54 185.0 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 dCMP_cyt_deam_1 PF00383.23 EGF77244.1 - 4.1e-26 90.8 2.7 6.3e-26 90.2 2.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGF77244.1 - 3.6e-13 49.5 0.2 6.2e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGF77244.1 - 0.0019 18.3 0.8 0.0039 17.3 0.8 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EGF77244.1 - 0.0053 16.7 0.8 0.0084 16.0 0.8 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain AAA_18 PF13238.6 EGF77244.1 - 0.0094 16.5 0.0 0.04 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain NAD1 PF18778.1 EGF77244.1 - 0.023 14.8 1.6 0.044 13.9 1.6 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 EGF77244.1 - 0.054 13.6 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 EGF77244.1 - 0.057 13.4 1.1 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase UL42 PF17638.2 EGF77245.1 - 0.028 14.4 1.6 0.19 11.7 0.0 2.8 3 0 0 3 3 3 0 HCMV UL42 RIC3 PF15361.6 EGF77245.1 - 0.082 13.3 0.0 16 5.9 0.0 2.7 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF5486 PF17588.2 EGF77245.1 - 0.16 11.8 1.4 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Tap-RNA_bind PF09162.10 EGF77245.1 - 0.2 11.5 1.7 3.4 7.6 0.0 3.1 3 0 0 3 3 3 0 Tap, RNA-binding Mac PF12464.8 EGF77246.1 - 0.3 11.3 3.5 0.19 12.0 1.1 1.9 2 0 0 2 2 2 0 Maltose acetyltransferase ArsA_HSP20 PF17886.1 EGF77249.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA ABC_membrane PF00664.23 EGF77250.1 - 2e-37 129.4 13.1 2.6e-37 129.0 13.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGF77250.1 - 2.1e-33 115.7 0.0 3.8e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGF77250.1 - 8.7e-09 35.1 0.5 6.4e-07 29.0 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF77250.1 - 0.0017 18.8 0.2 0.0048 17.3 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGF77250.1 - 0.0037 17.6 0.4 0.035 14.4 0.4 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF77250.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF77250.1 - 0.014 15.1 0.4 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGF77250.1 - 0.023 14.9 0.2 0.47 10.7 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGF77250.1 - 0.041 14.3 0.1 0.85 10.1 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EGF77250.1 - 0.046 13.4 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 EGF77250.1 - 0.053 13.8 0.2 0.64 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 EGF77250.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_21 PF13304.6 EGF77250.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Guanylate_kin PF00625.21 EGF77250.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase PHD PF00628.29 EGF77251.1 - 2.6e-13 49.6 9.0 3.1e-13 49.4 9.0 1.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGF77251.1 - 0.00038 20.0 3.6 0.00038 20.0 3.6 1.7 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 EGF77251.1 - 0.00097 19.2 6.1 0.0011 19.0 6.1 1.2 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 EGF77251.1 - 0.0051 17.1 4.5 0.012 15.9 4.7 1.5 1 1 1 2 2 2 1 Ring finger domain zf-RING_9 PF13901.6 EGF77251.1 - 0.073 13.0 5.1 0.11 12.5 5.1 1.3 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-CW PF07496.15 EGF77251.1 - 0.11 12.5 6.7 0.47 10.5 6.7 2.0 1 1 0 1 1 1 0 CW-type Zinc Finger Flavi_propep PF01570.17 EGF77251.1 - 0.16 12.0 4.0 0.17 11.9 4.0 1.2 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide DUF3716 PF12511.8 EGF77251.1 - 0.16 12.0 5.2 0.18 11.8 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) C1_1 PF00130.22 EGF77251.1 - 1 9.3 8.1 0.099 12.6 1.7 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OTU PF02338.19 EGF77252.1 - 2e-28 99.4 1.3 6.6e-28 97.8 0.1 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGF77252.1 - 4.8e-07 29.5 1.1 0.00017 21.1 0.0 2.7 2 1 1 3 3 3 2 Peptidase C65 Otubain Microtub_bind PF13931.6 EGF77252.1 - 0.0026 18.1 3.6 0.0041 17.5 3.6 1.2 1 0 0 1 1 1 1 Kinesin-associated microtubule-binding Band_3_cyto PF07565.13 EGF77252.1 - 0.98 9.2 5.6 1.4 8.6 5.2 1.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt4 PF06093.13 EGF77253.1 - 0.093 12.8 0.0 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger Mac PF12464.8 EGF77253.1 - 0.41 10.9 3.8 0.19 12.0 1.1 1.8 2 0 0 2 2 2 0 Maltose acetyltransferase DUF1221 PF06760.11 EGF77254.1 - 0.082 12.4 4.9 0.12 11.8 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) ALMT PF11744.8 EGF77254.1 - 0.54 9.0 3.9 0.59 8.9 3.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4246 PF14033.6 EGF77255.1 - 1e-81 275.4 0.0 3.5e-59 201.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) Arm PF00514.23 EGF77255.1 - 0.00031 20.7 0.1 0.0051 16.8 0.0 2.6 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EGF77255.1 - 0.073 12.5 0.2 0.36 10.2 0.1 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Peptidase_M36 PF02128.15 EGF77256.1 - 1.9e-142 474.8 5.8 2.5e-142 474.5 5.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF77256.1 - 4.4e-08 32.8 2.0 1e-07 31.6 2.0 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGF77256.1 - 0.032 14.1 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain PepSY PF03413.19 EGF77256.1 - 0.082 13.5 0.2 0.17 12.5 0.2 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF1977 PF09320.11 EGF77257.1 - 5e-24 84.6 0.6 5e-24 84.6 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EGF77257.1 - 1.4e-22 79.6 0.0 2.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RAP1 PF07218.11 EGF77257.1 - 1.1 7.4 3.8 1.5 7.0 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DEC-1_N PF04625.13 EGF77258.1 - 0.18 10.8 1.4 0.22 10.5 1.4 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GIDA PF01134.22 EGF77259.1 - 0.078 12.1 0.7 0.11 11.6 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fes1 PF08609.10 EGF77259.1 - 0.96 10.4 5.7 0.3 12.0 2.0 2.0 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 PSII_Pbs27 PF13326.6 EGF77259.1 - 2.4 8.5 6.5 1.9 8.8 3.8 2.2 2 2 0 2 2 2 0 Photosystem II Pbs27 DUF4407 PF14362.6 EGF77260.1 - 0.11 11.9 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Flu_B_M2 PF04772.12 EGF77261.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) DUF2203 PF09969.9 EGF77262.1 - 4.1e-07 30.7 19.8 0.025 15.3 0.3 5.2 4 2 2 6 6 6 3 Uncharacterized conserved protein (DUF2203) HTH_Tnp_Mu_1 PF02316.16 EGF77262.1 - 0.0023 18.1 13.9 2.6 8.2 0.0 4.8 6 0 0 6 6 6 3 Mu DNA-binding domain 2H-phosphodiest PF08975.10 EGF77262.1 - 0.018 15.0 1.5 46 4.0 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1868) DcrB PF08786.11 EGF77262.1 - 0.026 14.6 4.0 30 4.7 0.1 3.8 3 0 0 3 3 3 0 DcrB PhoR PF11808.8 EGF77262.1 - 0.075 13.4 1.3 2.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR DD_K PF12121.8 EGF77262.1 - 0.19 11.8 11.2 0.52 10.5 0.3 2.9 3 0 0 3 3 3 0 Dermaseptin Iron_permease PF04120.12 EGF77262.1 - 0.21 11.4 1.0 1.4e+02 2.2 0.0 3.9 3 0 0 3 3 3 0 Low affinity iron permease Serine_rich PF08824.10 EGF77262.1 - 0.33 10.9 5.8 35 4.4 0.0 3.7 3 0 0 3 3 3 0 Serine rich protein interaction domain FmdE PF02663.14 EGF77262.1 - 3.9 7.5 17.1 10 6.2 0.4 4.3 4 0 0 4 4 4 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF3450 PF11932.8 EGF77265.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Transposase_24 PF03004.14 EGF77265.1 - 0.011 15.9 0.9 0.011 15.9 0.9 2.3 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) MF_alpha_N PF05436.11 EGF77265.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF4246 PF14033.6 EGF77266.1 - 1.6e-84 284.7 0.2 2e-84 284.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) TRAM_LAG1_CLN8 PF03798.16 EGF77270.1 - 0.0017 18.2 23.2 0.0026 17.5 23.2 1.3 1 0 0 1 1 1 1 TLC domain Mpv17_PMP22 PF04117.12 EGF77271.1 - 2.7e-24 85.1 0.1 4.2e-24 84.5 0.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family CCDC50_N PF15295.6 EGF77272.1 - 0.0076 16.4 8.7 0.052 13.7 8.5 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus SNF2_N PF00176.23 EGF77273.1 - 3e-66 223.6 0.0 5.4e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF77273.1 - 1.3e-20 73.8 0.0 3.8e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EGF77273.1 - 1.8e-07 30.8 10.8 6.1e-07 29.2 10.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF77273.1 - 2.2e-07 30.8 7.5 8.4e-07 28.9 7.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGF77273.1 - 3.7e-07 29.9 10.4 7.4e-07 28.9 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF77273.1 - 4.6e-07 30.1 10.9 1.2e-06 28.7 10.3 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGF77273.1 - 1.1e-06 28.4 7.7 1.1e-06 28.4 7.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGF77273.1 - 2.6e-06 27.5 12.9 2.6e-06 27.5 12.9 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.15 EGF77273.1 - 2.7e-06 27.5 0.0 9.2e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-Nse PF11789.8 EGF77273.1 - 0.00015 21.5 5.1 0.00034 20.4 5.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EGF77273.1 - 0.00022 21.1 9.5 0.00046 20.1 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 EGF77273.1 - 0.00064 19.5 0.0 0.011 15.5 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-MIZ PF02891.20 EGF77273.1 - 0.0014 18.4 6.3 0.0029 17.3 6.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_6 PF14835.6 EGF77273.1 - 0.014 15.3 4.6 0.031 14.1 4.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rtf2 PF04641.12 EGF77273.1 - 0.052 12.9 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.7 EGF77273.1 - 0.061 13.6 6.1 0.18 12.1 6.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGF77273.1 - 0.064 13.1 11.4 0.36 10.7 11.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ERCC3_RAD25_C PF16203.5 EGF77273.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-ANAPC11 PF12861.7 EGF77273.1 - 0.12 12.5 3.7 0.26 11.4 3.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger 7tm_6 PF02949.20 EGF77273.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor zf-RING_10 PF16685.5 EGF77273.1 - 0.24 11.6 7.0 0.7 10.1 7.0 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 EGF77273.1 - 1.3 9.2 5.6 3.6 7.8 5.6 1.8 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_11 PF17123.5 EGF77273.1 - 2.6 7.9 9.8 3.1 7.6 8.0 2.2 2 0 0 2 2 1 0 RING-like zinc finger DsbC_N PF10411.9 EGF77275.1 - 0.034 13.6 0.5 48 3.5 0.0 3.8 3 2 1 4 4 4 0 Disulfide bond isomerase protein N-terminus DUF4588 PF15251.6 EGF77275.1 - 0.16 11.7 7.1 1.5 8.5 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4588) Metallophos PF00149.28 EGF77276.1 - 4.5e-08 33.8 3.6 5e-07 30.4 2.7 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Homeodomain PF00046.29 EGF77277.1 - 2.6e-14 52.8 3.2 6.3e-14 51.6 3.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGF77277.1 - 0.023 14.6 1.0 0.057 13.3 0.2 2.1 2 0 0 2 2 2 0 Homeobox KN domain Mpv17_PMP22 PF04117.12 EGF77278.1 - 1.7e-11 44.2 4.9 1.9e-11 44.0 1.9 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF1275 PF06912.11 EGF77278.1 - 0.0065 16.4 6.5 0.01 15.8 6.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) Peptidase_M48_N PF16491.5 EGF77279.1 - 2.4e-60 203.6 9.2 2.4e-60 203.6 9.2 2.7 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGF77279.1 - 8.1e-45 153.0 0.0 1.2e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 HupE_UreJ PF04955.12 EGF77279.1 - 0.052 13.0 0.2 0.095 12.2 0.2 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Peptidase_M56 PF05569.11 EGF77279.1 - 0.09 11.9 3.6 0.16 11.1 2.9 1.7 1 1 1 2 2 2 0 BlaR1 peptidase M56 Aldedh PF00171.22 EGF77282.1 - 1.4e-123 412.9 0.2 1.5e-123 412.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGF77282.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) adh_short PF00106.25 EGF77283.1 - 1.1e-27 96.7 0.9 1.3e-20 73.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF77283.1 - 1.1e-18 67.6 0.1 2.4e-12 46.9 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF77283.1 - 0.00037 20.4 0.3 0.00062 19.7 0.3 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EGF77283.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-H2C2_2 PF13465.6 EGF77284.1 - 5.3e-08 32.9 6.8 2.5e-07 30.8 0.4 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF77284.1 - 7.1e-07 29.5 9.0 9.4e-05 22.9 4.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF77284.1 - 1e-05 25.7 10.6 0.00086 19.6 5.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 EGF77284.1 - 0.00077 19.8 5.8 0.0012 19.1 1.3 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGF77284.1 - 0.09 12.8 1.5 0.09 12.8 1.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 EGF77284.1 - 2.3 8.7 5.5 0.33 11.4 0.8 1.8 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger adh_short_C2 PF13561.6 EGF77285.1 - 0.00057 19.5 0.0 0.00069 19.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TTL PF03133.15 EGF77287.1 - 1.3e-84 283.9 1.6 4e-83 279.0 1.6 2.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGF77287.1 - 1.3e-05 24.6 0.0 0.018 14.3 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp Complex1_LYR PF05347.15 EGF77288.1 - 1.8e-05 24.7 3.9 2.9e-05 24.0 3.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ComFB PF10719.9 EGF77288.1 - 0.011 15.9 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 0 Late competence development protein ComFB Complex1_LYR_1 PF13232.6 EGF77288.1 - 0.03 14.9 1.5 0.043 14.4 1.5 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EGF77288.1 - 0.099 13.4 2.1 0.14 13.0 2.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like MIF4G PF02854.19 EGF77288.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 MIF4G domain HMA PF00403.26 EGF77289.1 - 6.5e-10 39.3 0.2 7.1e-10 39.2 0.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain WD40 PF00400.32 EGF77290.1 - 3.6e-37 125.7 25.3 2.9e-05 24.7 0.3 11.4 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77290.1 - 2.5e-12 46.9 0.0 0.00048 20.4 0.0 7.2 5 2 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF77290.1 - 0.0096 14.9 0.1 6.7 5.6 0.0 3.2 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein HNH_2 PF13391.6 EGF77291.1 - 9.2e-05 22.5 0.1 0.00027 21.0 0.1 2.0 1 1 0 1 1 1 1 HNH endonuclease Paired_CXXCH_1 PF09699.10 EGF77291.1 - 0.16 11.7 4.4 2 8.2 0.3 2.7 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 EGF77291.1 - 0.25 11.3 2.3 4.1 7.5 0.1 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Pro_Al_protease PF02983.14 EGF77291.1 - 1.4 9.0 3.7 3 8.0 3.7 1.5 1 0 0 1 1 1 0 Alpha-lytic protease prodomain GntR PF00392.21 EGF77292.1 - 0.15 11.7 0.1 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family GyrB_insert PF18053.1 EGF77292.1 - 0.16 11.9 0.0 0.8 9.6 0.0 1.9 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain HMG_CoA_synt_N PF01154.17 EGF77294.1 - 2.5e-94 314.0 1.1 4e-94 313.4 1.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGF77294.1 - 2.7e-93 312.6 1.5 3.5e-93 312.3 1.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal adh_short PF00106.25 EGF77295.1 - 2.3e-40 138.2 0.1 2.7e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF77295.1 - 4.1e-28 98.5 0.4 4.6e-28 98.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF77295.1 - 3e-11 43.5 0.1 4.8e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF77295.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sin3a_C PF16879.5 EGF77296.1 - 6.1e-65 219.8 2.6 6.1e-65 219.8 2.6 2.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EGF77296.1 - 1.7e-48 162.5 7.8 1.9e-18 66.3 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGF77296.1 - 3.4e-35 120.0 0.1 1.1e-34 118.4 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Flavokinase PF01687.17 EGF77297.1 - 7.4e-33 113.2 0.0 9.1e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Meth_synt_2 PF01717.18 EGF77298.1 - 1.1e-153 511.2 0.0 2.1e-146 487.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGF77298.1 - 2.4e-113 378.8 0.0 1e-105 353.7 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGF77298.1 - 0.016 14.4 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) CNH PF00780.22 EGF77299.1 - 1.1e-46 159.7 0.0 8.4e-46 156.8 0.0 2.1 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGF77299.1 - 1.9e-29 103.2 0.3 2.1e-26 93.3 0.3 2.5 1 1 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EGF77299.1 - 2.2e-12 47.3 0.0 4.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 EGF77299.1 - 0.15 12.3 0.1 0.76 10.0 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PAPS_reduct PF01507.19 EGF77300.1 - 2.3e-27 96.1 0.0 2.9e-19 69.8 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Sld5 PF05916.11 EGF77301.1 - 1.8e-21 76.6 0.0 2.4e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein DUF2428 PF10350.9 EGF77302.1 - 4.7e-64 216.3 0.6 4.7e-64 216.3 0.6 2.2 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) AAA PF00004.29 EGF77303.1 - 2.9e-18 66.6 0.0 5.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGF77303.1 - 2.8e-14 53.2 0.0 1e-11 44.9 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGF77303.1 - 3.5e-12 46.6 0.1 7.5e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.12 EGF77303.1 - 2.5e-07 30.6 0.1 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGF77303.1 - 2.6e-07 31.2 0.1 9.9e-05 22.8 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGF77303.1 - 2.5e-06 27.8 0.1 0.00041 20.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGF77303.1 - 9.8e-06 25.6 0.1 3.9e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGF77303.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF77303.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 EGF77303.1 - 1.6e-05 24.8 0.1 3.6e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGF77303.1 - 6e-05 23.0 0.0 0.00016 21.6 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EGF77303.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGF77303.1 - 0.0002 21.7 0.0 0.00074 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGF77303.1 - 0.0003 20.3 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGF77303.1 - 0.00033 19.9 0.0 0.00049 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 EGF77303.1 - 0.00076 19.8 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 EGF77303.1 - 0.0014 18.7 0.0 0.018 15.0 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EGF77303.1 - 0.0019 18.7 0.0 0.0031 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF77303.1 - 0.0024 18.4 0.0 0.0052 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGF77303.1 - 0.003 17.4 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGF77303.1 - 0.0036 16.6 0.2 0.054 12.7 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 EGF77303.1 - 0.0044 16.3 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain DEAD PF00270.29 EGF77303.1 - 0.0048 16.7 0.4 0.12 12.1 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase NACHT PF05729.12 EGF77303.1 - 0.01 15.8 0.1 6.9 6.6 0.0 2.9 2 1 0 2 2 2 0 NACHT domain TniB PF05621.11 EGF77303.1 - 0.011 15.2 0.0 0.16 11.4 0.0 2.4 3 0 0 3 3 2 0 Bacterial TniB protein AAA_25 PF13481.6 EGF77303.1 - 0.016 14.8 0.0 0.041 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF77303.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGF77303.1 - 0.023 15.2 0.0 0.08 13.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 EGF77303.1 - 0.026 14.0 0.0 0.53 9.7 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein IstB_IS21 PF01695.17 EGF77303.1 - 0.026 14.2 0.0 0.057 13.2 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 EGF77303.1 - 0.04 13.0 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain RNA_helicase PF00910.22 EGF77303.1 - 0.046 14.1 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EGF77303.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EGF77303.1 - 0.064 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGF77303.1 - 0.088 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGF77303.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Bot1p PF12298.8 EGF77304.1 - 4.6e-25 88.8 0.1 4.6e-25 88.8 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein zf-NOSIP PF15906.5 EGF77306.1 - 1.3e-14 54.1 0.7 2.7e-14 53.0 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein FlgN PF05130.12 EGF77306.1 - 0.4 11.2 3.5 4 7.9 0.5 2.2 2 0 0 2 2 2 0 FlgN protein zf-RING_2 PF13639.6 EGF77306.1 - 0.74 10.2 21.1 1.4 9.4 3.6 2.4 2 0 0 2 2 2 0 Ring finger domain Sec3_C PF09763.9 EGF77307.1 - 7.1e-150 500.7 7.4 1.2e-149 499.9 7.4 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec3 Vps52 PF04129.12 EGF77307.1 - 5.6e-06 25.4 7.5 5.6e-06 25.4 7.5 2.6 2 2 0 3 3 3 1 Vps52 / Sac2 family Sec3-PIP2_bind PF15277.6 EGF77307.1 - 4.2e-05 23.6 0.4 0.00013 22.0 0.4 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF3450 PF11932.8 EGF77307.1 - 0.018 14.4 1.9 0.045 13.0 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RNA_pol_Rpb1_5 PF04998.17 EGF77307.1 - 0.15 11.5 0.6 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Arm PF00514.23 EGF77308.1 - 5.8e-33 111.9 19.1 3.3e-07 30.1 0.0 9.8 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGF77308.1 - 5.3e-21 72.9 7.9 0.017 15.3 0.0 7.7 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 EGF77308.1 - 2.1e-17 63.3 10.3 0.0004 20.7 0.6 5.3 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 EGF77308.1 - 1.4e-14 54.2 18.0 0.00035 21.0 0.5 6.5 5 2 3 8 8 8 5 HEAT-like repeat Cnd1 PF12717.7 EGF77308.1 - 1.5e-13 51.1 0.1 0.0014 18.7 0.0 4.0 1 1 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGF77308.1 - 1.7e-08 33.5 1.6 0.00031 19.4 0.2 3.7 2 1 1 3 3 3 2 Adaptin N terminal region CHASE6_C PF17150.4 EGF77308.1 - 5.4e-06 27.0 0.4 1.5 9.6 0.1 5.6 5 1 1 6 6 5 1 C-terminal domain of two-partite extracellular sensor domain Proteasom_PSMB PF10508.9 EGF77308.1 - 1.8e-05 23.5 0.7 0.00073 18.2 0.1 2.5 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.8 EGF77308.1 - 3.6e-05 23.5 0.2 0.19 11.2 0.0 3.1 2 1 1 3 3 3 2 CLASP N terminal Arm_2 PF04826.13 EGF77308.1 - 7.5e-05 22.3 0.3 7.2 6.0 0.1 4.4 1 1 4 5 5 5 1 Armadillo-like DNA_alkylation PF08713.11 EGF77308.1 - 0.00016 21.5 0.0 3.4 7.3 0.0 4.5 2 1 2 5 5 5 1 DNA alkylation repair enzyme RICTOR_V PF14668.6 EGF77308.1 - 0.00035 20.7 0.2 0.23 11.7 0.0 3.9 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Rcd1 PF04078.13 EGF77308.1 - 0.00036 19.9 0.0 0.92 8.8 0.0 2.5 2 0 0 2 2 2 2 Cell differentiation family, Rcd1-like HEAT_PBS PF03130.16 EGF77308.1 - 0.00097 19.6 13.7 1.1 10.2 0.0 6.2 6 1 0 6 6 5 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGF77308.1 - 0.017 15.7 0.0 0.53 10.9 0.0 3.0 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Mo25 PF08569.11 EGF77308.1 - 0.023 14.1 0.0 3.6 6.9 0.0 2.6 1 1 1 2 2 2 0 Mo25-like DUF3731 PF12531.8 EGF77308.1 - 0.038 13.8 0.6 12 5.6 0.0 3.3 3 1 0 3 3 3 0 DNA-K related protein HEAT_UF PF18817.1 EGF77308.1 - 0.057 13.7 0.2 0.6 10.4 0.0 2.9 3 0 0 3 3 1 0 Repeat of uncharacterized protein PH0542 RTP1_C1 PF10363.9 EGF77308.1 - 0.06 13.5 0.2 0.7 10.1 0.0 2.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 API5 PF05918.11 EGF77308.1 - 0.064 12.1 0.0 14 4.3 0.2 2.9 1 1 2 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Gcn1_N PF12074.8 EGF77308.1 - 0.089 12.1 1.8 3.4 6.9 0.3 3.3 1 1 2 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal V-ATPase_H_C PF11698.8 EGF77308.1 - 0.1 12.7 0.0 12 6.0 0.0 3.6 3 1 1 4 4 4 0 V-ATPase subunit H RRM_1 PF00076.22 EGF77309.1 - 4.5e-16 58.4 0.1 6.2e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGF77309.1 - 5.7e-09 35.6 2.9 9.5e-09 34.9 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGF77309.1 - 0.00033 20.5 0.1 0.00054 19.9 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Nup35_RRM_2 PF14605.6 EGF77309.1 - 0.0018 18.2 0.0 0.0049 16.8 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCHC_5 PF14787.6 EGF77309.1 - 0.0043 16.7 2.5 0.0089 15.7 2.5 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EGF77309.1 - 0.0096 15.7 1.9 0.017 15.0 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_3 PF08777.11 EGF77309.1 - 0.015 15.3 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif RRM_7 PF16367.5 EGF77309.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Ribul_P_3_epim PF00834.19 EGF77310.1 - 1.2e-70 237.0 0.1 1.3e-70 236.8 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 EGF77310.1 - 0.00084 18.7 0.2 0.0021 17.4 0.1 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase PEP_hydrolase PF09370.10 EGF77310.1 - 0.097 11.9 0.6 0.67 9.1 0.0 2.4 2 1 1 3 3 3 0 Phosphoenolpyruvate hydrolase-like QRPTase_C PF01729.19 EGF77310.1 - 0.14 11.9 0.1 0.39 10.5 0.0 1.9 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PB1 PF00564.24 EGF77311.1 - 0.019 14.9 0.1 0.081 12.9 0.0 2.1 1 1 0 1 1 1 0 PB1 domain Alpha_kinase PF02816.18 EGF77318.1 - 6.3e-46 156.8 0.3 7.5e-46 156.6 0.3 1.1 1 0 0 1 1 1 1 Alpha-kinase family Pkinase PF00069.25 EGF77319.1 - 1.5e-76 257.3 0.1 2.7e-76 256.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77319.1 - 1.2e-51 175.5 0.0 2.3e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGF77319.1 - 1.5e-21 76.5 0.2 4.9e-21 74.8 0.2 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 EGF77319.1 - 1.8e-12 47.7 0.4 3.7e-12 46.7 0.4 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EGF77319.1 - 2.7e-09 36.8 0.0 6.5e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF77319.1 - 1.5e-06 27.3 1.6 9e-06 24.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Cut8 PF08559.10 EGF77319.1 - 0.013 15.2 3.0 0.028 14.0 3.0 1.6 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Seadorna_VP7 PF07387.11 EGF77319.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGF77319.1 - 0.015 15.2 0.0 0.1 12.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF77319.1 - 0.046 12.7 7.3 0.21 10.5 7.3 1.9 1 1 0 1 1 1 0 Haspin like kinase domain PH_11 PF15413.6 EGF77319.1 - 2.2 8.8 6.0 8.3 6.9 0.9 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain BolA PF01722.18 EGF77320.1 - 5.5e-11 42.6 0.0 1.9e-10 40.9 0.0 1.7 1 1 1 2 2 2 1 BolA-like protein Elong_Iki1 PF10483.9 EGF77321.1 - 4.1e-17 62.6 4.8 7e-11 42.2 0.0 2.0 1 1 1 2 2 2 2 Elongator subunit Iki1 WD40 PF00400.32 EGF77322.1 - 1.4e-24 85.9 2.6 9.8e-06 26.2 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77322.1 - 9.2e-10 38.7 0.0 0.049 13.9 0.0 5.5 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGF77322.1 - 0.00031 19.4 0.0 0.0056 15.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGF77322.1 - 0.01 14.8 0.0 1.5 7.8 0.0 3.0 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RhoGAP PF00620.27 EGF77323.1 - 5.9e-11 42.4 0.0 8.9e-07 28.9 0.0 2.6 2 1 0 2 2 2 2 RhoGAP domain NDUF_B12 PF08122.12 EGF77323.1 - 7.5e-11 41.9 0.1 1.8e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Exo_endo_phos PF03372.23 EGF77323.1 - 4.7e-10 39.4 0.0 2.1e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family INPP5B_PH PF16776.5 EGF77323.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain RMI1_N PF08585.12 EGF77324.1 - 3.3e-21 76.1 1.4 4.5e-21 75.6 0.1 1.9 2 0 0 2 2 2 1 RecQ mediated genome instability protein RMI1_C PF16099.5 EGF77324.1 - 1.1e-08 35.0 0.0 2.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold EF-hand_4 PF12763.7 EGF77325.1 - 0.29 11.1 2.9 6.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand UMPH-1 PF05822.12 EGF77326.1 - 9.6e-81 270.9 1.9 1.2e-80 270.6 1.9 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 EGF77326.1 - 4.3e-08 33.8 0.4 1.6e-07 31.9 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EGF77326.1 - 0.0038 17.0 1.5 0.5 10.1 0.0 2.9 4 0 0 4 4 4 2 NLI interacting factor-like phosphatase Meckelin PF09773.9 EGF77326.1 - 0.061 11.4 0.0 0.08 11.0 0.0 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) UVR PF02151.19 EGF77327.1 - 3.3e-05 23.5 3.4 0.16 11.8 0.3 3.2 3 0 0 3 3 3 2 UvrB/uvrC motif DUF1086 PF06461.11 EGF77327.1 - 0.0041 17.0 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) zf_UBZ PF18439.1 EGF77327.1 - 0.015 14.9 0.9 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 EGF77327.1 - 1.7 8.7 6.9 1.2 9.2 3.9 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 EGF77327.1 - 1.9 8.9 6.5 2 8.8 3.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GMP_PDE_delta PF05351.11 EGF77328.1 - 8.4e-25 87.7 0.0 9.5e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit zf-MYND PF01753.18 EGF77329.1 - 3.7e-10 39.7 14.5 3.7e-10 39.7 14.5 2.0 2 0 0 2 2 2 1 MYND finger SET PF00856.28 EGF77329.1 - 0.00015 22.2 0.2 0.00041 20.8 0.2 1.8 1 1 0 1 1 1 1 SET domain AdoMet_dc PF02675.15 EGF77329.1 - 0.075 13.3 0.2 0.84 9.9 0.2 2.4 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase zf-C6H2 PF15801.5 EGF77329.1 - 0.11 12.8 8.7 0.43 10.9 8.7 2.0 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SH3_9 PF14604.6 EGF77330.1 - 2.2e-06 27.4 0.0 5.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF77330.1 - 0.0031 17.1 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain WD40 PF00400.32 EGF77331.1 - 1.5e-14 54.1 4.4 0.0034 18.2 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77331.1 - 1.4e-05 25.3 0.4 0.019 15.3 0.1 4.6 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF77331.1 - 0.0015 17.2 0.6 0.15 10.6 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGF77331.1 - 0.013 16.0 0.0 34 5.1 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Band_7 PF01145.25 EGF77333.1 - 7.1e-26 91.3 2.1 9.3e-26 90.9 2.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGF77333.1 - 0.13 12.0 0.3 0.21 11.3 0.3 1.4 1 1 0 1 1 1 0 SPFH domain-Band 7 family DHC_N1 PF08385.12 EGF77334.1 - 1.4e-178 595.0 9.0 9.5e-177 589.0 3.5 2.9 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 MT PF12777.7 EGF77334.1 - 5.8e-157 522.1 20.4 2.4e-156 520.1 15.8 3.0 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 EGF77334.1 - 3.3e-156 519.3 0.1 8.4e-154 511.4 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF77334.1 - 8.4e-129 430.1 11.2 8.4e-129 430.1 11.2 3.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGF77334.1 - 7e-99 330.9 0.1 3e-98 328.8 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGF77334.1 - 2.6e-98 328.5 0.0 1.7e-97 325.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGF77334.1 - 8.2e-84 280.1 0.1 2.5e-83 278.6 0.1 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF77334.1 - 1.4e-74 249.6 0.5 6.1e-68 227.9 0.0 3.7 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF77334.1 - 2.7e-56 189.9 0.1 4.1e-52 176.3 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGF77334.1 - 4e-40 136.0 0.9 4e-40 136.0 0.9 2.8 2 0 0 2 2 1 1 AAA+ lid domain Dynein_heavy PF03028.15 EGF77334.1 - 3.6e-37 127.1 0.1 3.3e-36 124.0 0.0 2.9 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGF77334.1 - 6.8e-25 87.7 0.0 1.1e-12 48.2 0.0 5.9 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGF77334.1 - 3.4e-23 82.1 0.9 1.6e-22 80.0 0.9 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EGF77334.1 - 1.6e-08 35.2 0.0 0.029 14.7 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGF77334.1 - 5.5e-07 29.9 0.0 0.75 10.1 0.0 4.4 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 EGF77334.1 - 1.1e-06 29.1 0.7 0.27 11.7 0.0 5.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGF77334.1 - 0.00025 21.4 0.5 8.9 6.6 0.0 4.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGF77334.1 - 0.00045 20.8 1.2 2.1 8.9 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 EGF77334.1 - 0.00088 19.0 0.2 24 4.6 0.3 4.1 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EGF77334.1 - 0.0011 19.3 0.1 8.6 6.8 0.0 4.0 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 EGF77334.1 - 0.0016 19.0 2.2 0.67 10.5 0.0 4.2 4 0 0 4 4 3 1 ABC transporter Sigma54_activ_2 PF14532.6 EGF77334.1 - 0.0044 17.1 0.0 2.7 8.1 0.0 3.2 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.15 EGF77334.1 - 0.0046 16.9 0.0 14 5.5 0.0 4.1 3 0 0 3 3 3 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGF77334.1 - 0.0054 16.7 0.0 1.6 8.6 0.0 3.8 3 0 0 3 3 3 1 RsgA GTPase AAA_14 PF13173.6 EGF77334.1 - 0.0071 16.4 0.0 1.3 9.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EGF77334.1 - 0.0083 15.8 0.0 3.7 7.2 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF815 PF05673.13 EGF77334.1 - 0.011 14.9 0.0 5.8 6.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 EGF77334.1 - 0.015 14.9 0.1 0.51 9.9 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 EGF77334.1 - 0.022 15.0 0.0 14 5.9 0.0 3.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGF77334.1 - 0.025 14.3 0.2 27 4.6 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGF77334.1 - 0.061 12.7 0.3 25 4.2 0.0 3.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGF77334.1 - 0.084 12.9 0.4 12 6.0 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EGF77334.1 - 0.23 11.2 1.4 4.1 7.1 0.0 3.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EGF77334.1 - 0.36 10.7 4.2 0.73 9.7 0.0 3.5 4 0 0 4 4 4 0 NACHT domain SH3_9 PF14604.6 EGF77335.1 - 7e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF77335.1 - 8.5e-08 31.7 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF77336.1 - 2.2e-07 30.6 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF77336.1 - 1.2e-06 28.0 0.1 2e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_1 PF00018.28 EGF77337.1 - 2.5e-06 27.0 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF77337.1 - 8.6e-06 25.5 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GTP_EFTU PF00009.27 EGF77338.1 - 1.3e-49 168.4 0.0 2.2e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGF77338.1 - 3.4e-14 52.7 0.0 8.5e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGF77338.1 - 7.7e-06 26.2 1.2 2e-05 24.9 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF77338.1 - 1.8e-05 24.8 0.0 5.5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF77338.1 - 0.00038 20.0 0.1 0.0024 17.4 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF77338.1 - 0.019 14.9 0.2 0.67 9.8 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 EGF77338.1 - 0.033 13.5 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 EGF77338.1 - 0.11 11.9 0.4 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PPR_2 PF13041.6 EGF77340.1 - 0.0023 18.1 0.3 4.1 7.7 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family ATP-synt_Eps PF04627.13 EGF77341.1 - 1e-17 63.8 0.9 1.3e-17 63.5 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Tyrosinase PF00264.20 EGF77342.1 - 7e-43 147.5 11.4 3.8e-42 145.1 6.0 3.0 2 1 0 2 2 2 1 Common central domain of tyrosinase Mito_carr PF00153.27 EGF77343.1 - 3.2e-67 222.5 4.2 4.1e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGF77343.1 - 0.066 13.4 0.4 16 5.8 0.1 3.3 2 1 1 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase ABC_trans_CmpB PF06541.11 EGF77343.1 - 0.3 11.3 3.3 0.13 12.5 0.7 1.6 2 0 0 2 2 2 0 Putative ABC-transporter type IV Cys_Met_Meta_PP PF01053.20 EGF77344.1 - 2.3e-33 115.3 0.0 1.8e-32 112.3 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGF77344.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II EamA PF00892.20 EGF77346.1 - 4.6e-06 26.9 10.4 2.4e-05 24.5 10.4 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EGF77346.1 - 0.0011 19.0 1.5 0.0014 18.6 1.2 1.4 1 1 0 1 1 1 1 Putative transmembrane family 234 Apq12 PF12716.7 EGF77346.1 - 2.7 8.0 7.2 0.2 11.6 1.0 2.2 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis SQS_PSY PF00494.19 EGF77347.1 - 1.7e-36 126.1 0.0 2.1e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase EF-hand_1 PF00036.32 EGF77348.1 - 7.9e-19 65.7 9.6 5.4e-07 28.7 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EGF77348.1 - 6.6e-17 61.7 1.0 1.1e-08 35.4 0.5 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGF77348.1 - 6.6e-16 56.8 6.6 5.2e-06 26.0 0.1 4.9 5 1 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 EGF77348.1 - 3.3e-10 39.0 2.8 4.7e-05 22.7 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGF77348.1 - 2.1e-09 37.1 8.9 2.2e-06 27.4 0.4 3.7 2 1 2 4 4 4 3 EF-hand domain pair DUF1456 PF07308.13 EGF77348.1 - 0.012 16.0 0.3 2.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Dockerin_1 PF00404.18 EGF77348.1 - 0.016 15.4 0.3 0.099 12.8 0.1 2.1 2 1 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 EGF77348.1 - 0.094 12.6 0.0 2 8.3 0.0 2.3 1 1 0 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.7 EGF77348.1 - 0.24 11.4 3.8 7.4 6.6 0.3 3.1 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand CBS PF00571.28 EGF77349.1 - 1.5e-22 79.8 13.8 9e-06 26.1 0.1 5.2 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 EGF77349.1 - 8.5e-06 25.6 0.4 2.4e-05 24.2 0.4 1.7 1 0 0 1 1 1 1 PB1 domain DUF4154 PF13689.6 EGF77349.1 - 0.081 13.2 0.3 21 5.3 0.1 2.5 2 0 0 2 2 2 0 YfiR/HmsC-like HLH PF00010.26 EGF77350.1 - 4.6e-13 48.9 0.6 8.5e-13 48.0 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ada_Zn_binding PF02805.16 EGF77350.1 - 0.057 13.4 2.1 0.062 13.3 0.2 2.0 2 0 0 2 2 2 0 Metal binding domain of Ada ALG3 PF05208.13 EGF77352.1 - 1.1e-137 459.3 23.5 1.4e-137 459.0 23.5 1.1 1 0 0 1 1 1 1 ALG3 protein DUF4733 PF15878.5 EGF77352.1 - 0.022 15.2 0.1 0.13 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4733) FUN14 PF04930.15 EGF77352.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 FUN14 family CAP_N PF01213.19 EGF77353.1 - 2.8e-102 342.4 2.2 3.5e-102 342.1 2.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGF77353.1 - 1.6e-61 206.5 2.5 2.4e-61 206.0 2.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGF77353.1 - 0.00013 21.7 0.6 0.00026 20.7 0.6 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C WH2 PF02205.20 EGF77353.1 - 0.021 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 WH2 motif ALIX_LYPXL_bnd PF13949.6 EGF77353.1 - 0.067 12.5 0.5 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PPR_2 PF13041.6 EGF77354.1 - 5.5e-12 45.7 0.2 0.041 14.1 0.0 6.9 6 2 1 7 7 7 3 PPR repeat family PPR PF01535.20 EGF77354.1 - 2.3e-09 36.9 4.8 0.42 11.0 0.0 7.7 8 0 0 8 8 8 1 PPR repeat PPR_3 PF13812.6 EGF77354.1 - 8.9e-07 28.9 2.8 0.033 14.3 0.0 5.4 4 1 2 6 6 6 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGF77354.1 - 0.00057 19.3 0.0 3.4 7.0 0.0 3.3 3 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGF77354.1 - 0.026 14.2 0.3 5.7 6.7 0.0 4.2 5 0 0 5 5 5 0 PPR repeat TPR_1 PF00515.28 EGF77354.1 - 0.037 13.8 0.0 6.7 6.7 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF77354.1 - 0.063 13.4 0.0 21 5.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Exog_C PF18026.1 EGF77354.1 - 0.12 12.5 0.0 0.51 10.4 0.0 2.1 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain TPR_MalT PF17874.1 EGF77354.1 - 0.16 11.3 1.4 1.8 7.8 0.0 2.7 2 1 1 3 3 3 0 MalT-like TPR region MTS PF05175.14 EGF77355.1 - 4.7e-09 36.0 0.1 6.6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGF77355.1 - 9.1e-08 31.8 0.5 1.2e-07 31.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EGF77355.1 - 1.6e-05 24.6 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EGF77355.1 - 2.6e-05 24.9 0.1 5.8e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGF77355.1 - 8.4e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EGF77355.1 - 0.0038 17.0 0.5 0.0057 16.4 0.5 1.3 1 1 0 1 1 1 1 Methyltransferase domain Pfg27 PF09216.10 EGF77355.1 - 0.014 15.2 0.4 0.022 14.6 0.4 1.3 1 0 0 1 1 1 0 Pfg27 Methyltransf_11 PF08241.12 EGF77355.1 - 0.014 16.0 0.1 0.033 14.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EGF77355.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Phosphodiest PF01663.22 EGF77356.1 - 5.1e-85 286.2 0.5 5.9e-85 286.0 0.5 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 EGF77356.1 - 0.017 15.2 0.1 0.076 13.1 0.1 1.9 2 0 0 2 2 2 0 PglZ domain Sulfatase PF00884.23 EGF77356.1 - 0.021 14.2 0.3 0.69 9.3 0.3 2.4 1 1 0 1 1 1 0 Sulfatase zf-RING_2 PF13639.6 EGF77357.1 - 4.4e-13 49.3 8.8 1.1e-12 48.1 8.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGF77357.1 - 1.9e-08 34.0 2.9 1.9e-08 34.0 2.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF77357.1 - 2e-08 33.9 9.4 5e-08 32.7 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF77357.1 - 2.3e-05 24.6 13.6 2.7e-05 24.4 11.4 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGF77357.1 - 0.00013 21.7 9.0 0.00013 21.7 9.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGF77357.1 - 0.0002 21.2 12.0 0.00043 20.1 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF77357.1 - 0.0015 18.5 5.7 0.0038 17.2 5.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGF77357.1 - 0.0047 16.9 11.2 0.01 15.8 11.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain NOG1_N PF17835.1 EGF77357.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 NOG1 N-terminal helical domain PRA1 PF03208.19 EGF77358.1 - 4.2e-35 120.5 1.2 4.8e-35 120.3 1.2 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF5325 PF17259.2 EGF77358.1 - 3.8 7.5 6.5 0.69 9.8 1.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5325) 2TM PF13239.6 EGF77358.1 - 7.5 6.9 11.7 1.3 9.4 1.6 2.3 2 0 0 2 2 2 0 2TM domain DEAD PF00270.29 EGF77359.1 - 4.6e-46 156.8 0.0 3.6e-45 153.9 0.0 2.5 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF77359.1 - 6.3e-29 100.6 0.0 6.8e-28 97.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF77359.1 - 2.8e-06 27.5 0.0 3.3e-05 24.0 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 EGF77359.1 - 0.0058 16.7 2.2 0.011 15.8 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle PRAI PF00697.22 EGF77359.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CxC3 PF18804.1 EGF77359.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases zf-CCHC_4 PF14392.6 EGF77359.1 - 0.21 11.4 0.6 0.52 10.1 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGF77359.1 - 0.46 10.3 1.6 0.9 9.3 1.6 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger MSA-2c PF12238.8 EGF77360.1 - 1.9 8.4 9.7 0.16 11.9 4.4 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF4246 PF14033.6 EGF77362.1 - 2.9e-93 313.5 0.0 4.3e-93 312.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF5578 PF17741.1 EGF77362.1 - 0.12 11.8 0.1 0.36 10.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5578) Tup_N PF08581.10 EGF77363.1 - 0.0036 17.6 10.5 0.0073 16.6 7.8 2.3 2 0 0 2 2 2 1 Tup N-terminal DUF2959 PF11172.8 EGF77363.1 - 0.049 13.8 5.4 0.097 12.8 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Phage_pRha PF09669.10 EGF77363.1 - 0.052 14.1 0.9 0.13 12.9 0.9 1.6 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Com_YlbF PF06133.11 EGF77363.1 - 0.13 12.9 10.2 0.19 12.3 8.1 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF5344 PF17279.2 EGF77363.1 - 0.18 12.4 12.0 1 10.0 0.3 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5344) CENP-H PF05837.12 EGF77363.1 - 0.24 11.8 10.2 0.15 12.5 8.2 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PHM7_cyt PF14703.6 EGF77363.1 - 0.54 10.5 8.5 0.72 10.1 7.4 1.7 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ExsD PF16806.5 EGF77363.1 - 0.72 9.7 5.6 1.3 8.9 5.6 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD OmpH PF03938.14 EGF77363.1 - 1.2 9.4 10.5 2.2 8.6 10.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PRC2_HTH_1 PF18118.1 EGF77363.1 - 2.9 8.8 7.0 10 7.0 0.1 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain adh_short PF00106.25 EGF77364.1 - 1.3e-54 184.7 0.7 1.9e-54 184.1 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF77364.1 - 2.2e-43 148.5 0.2 2.8e-43 148.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF77364.1 - 4.2e-17 62.6 0.1 5.6e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGF77364.1 - 2.4e-07 30.2 0.4 3.5e-07 29.7 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGF77364.1 - 0.00071 19.1 0.2 0.0029 17.1 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Helicase_RecD PF05127.14 EGF77364.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Helicase DUF1776 PF08643.10 EGF77364.1 - 0.036 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_M20 PF01546.28 EGF77365.1 - 2.5e-33 115.5 0.0 3.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGF77365.1 - 1e-11 44.7 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGF77365.1 - 0.0013 18.4 0.0 0.05 13.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 IstB_IS21 PF01695.17 EGF77367.1 - 0.032 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cse1 PF08506.10 EGF77368.1 - 1.7e-133 445.0 1.5 2.6e-133 444.4 1.5 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EGF77368.1 - 1.3e-118 396.3 1.0 3.7e-118 394.8 1.0 1.8 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGF77368.1 - 9.3e-16 57.5 0.2 4e-14 52.3 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 EGF77368.1 - 0.016 15.4 0.1 18 5.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat FIST PF08495.10 EGF77368.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 FIST N domain Xpo1 PF08389.12 EGF77368.1 - 0.29 11.2 7.5 0.55 10.3 0.0 4.4 6 0 0 6 6 6 0 Exportin 1-like protein Kinesin PF00225.23 EGF77370.1 - 1.2e-106 356.5 1.9 1.3e-106 356.3 1.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF77370.1 - 1e-26 93.7 0.1 1.8e-26 92.9 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding DUF2118 PF09891.9 EGF77370.1 - 0.003 17.5 0.4 0.025 14.5 0.1 2.6 2 1 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2118) Gti1_Pac2 PF09729.9 EGF77371.1 - 3.5e-39 134.8 6.1 2.2e-33 115.8 0.0 2.8 2 2 1 3 3 3 2 Gti1/Pac2 family FA_desaturase PF00487.24 EGF77372.1 - 3.6e-29 102.4 19.8 5.9e-29 101.7 19.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGF77372.1 - 9.3e-10 38.8 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Sensor PF13796.6 EGF77372.1 - 0.053 13.6 0.1 0.053 13.6 0.1 1.7 2 0 0 2 2 2 0 Putative sensor AAA_18 PF13238.6 EGF77373.1 - 1.7e-28 99.8 0.1 3.2e-28 98.9 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 EGF77373.1 - 1.2e-08 35.5 0.3 5.7e-08 33.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EGF77373.1 - 2.1e-05 24.8 0.1 4e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGF77373.1 - 3e-05 23.2 0.1 4.6e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ADK PF00406.22 EGF77373.1 - 0.00011 22.4 0.5 0.0092 16.1 0.1 2.4 1 1 1 2 2 2 1 Adenylate kinase AAA PF00004.29 EGF77373.1 - 0.0007 20.0 1.7 0.0011 19.3 0.4 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGF77373.1 - 0.00083 19.2 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF77373.1 - 0.0024 18.0 0.2 0.11 12.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 EGF77373.1 - 0.0027 17.1 0.6 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 KaiC ResIII PF04851.15 EGF77373.1 - 0.0055 16.7 0.1 0.012 15.6 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EGF77373.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SKI PF01202.22 EGF77373.1 - 0.012 15.7 0.2 0.02 15.0 0.2 1.4 1 1 0 1 1 1 0 Shikimate kinase FtsK_SpoIIIE PF01580.18 EGF77373.1 - 0.017 14.5 0.2 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EGF77373.1 - 0.024 14.9 0.5 0.063 13.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGF77373.1 - 0.027 14.2 0.2 0.12 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGF77373.1 - 0.028 13.7 0.1 0.1 11.9 0.0 2.0 2 1 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 EGF77373.1 - 0.033 13.9 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGF77373.1 - 0.056 13.8 3.8 0.099 13.0 3.8 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EGF77373.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGF77373.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGF77373.1 - 0.082 12.9 0.2 0.16 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGF77373.1 - 0.085 12.4 0.4 0.29 10.7 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EGF77373.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGF77373.1 - 0.14 11.9 0.8 0.2 11.4 0.1 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 EGF77373.1 - 0.18 11.7 2.4 1.8 8.4 0.1 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 EGF77373.1 - 0.29 11.0 3.9 0.15 12.0 1.3 1.8 1 1 1 2 2 2 0 NTPase CAF1C_H4-bd PF12265.8 EGF77374.1 - 2e-18 66.4 0.2 7.3e-17 61.4 0.0 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGF77374.1 - 1.3e-14 54.3 17.1 9.2e-08 32.6 0.8 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77374.1 - 1.4e-07 31.7 1.8 0.0066 16.7 0.1 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain UBA_4 PF14555.6 EGF77375.1 - 0.03 14.1 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain LysM PF01476.20 EGF77375.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 LysM domain RNase_H PF00075.24 EGF77377.1 - 1.4e-18 67.5 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 RNase H N1221 PF07923.13 EGF77379.1 - 1.8e-51 175.1 4.9 3.8e-51 174.0 4.1 1.9 2 0 0 2 2 2 1 N1221-like protein DUF3402 PF11882.8 EGF77379.1 - 1.9e-18 66.8 0.0 3.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) DUF1205 PF06722.12 EGF77379.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) DUF3402 PF11882.8 EGF77380.1 - 4.4e-38 131.6 0.1 5.4e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) Dimer_Tnp_hAT PF05699.14 EGF77381.1 - 5.3e-19 67.8 0.1 5.7e-19 67.7 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ABC_membrane PF00664.23 EGF77382.1 - 1.1e-55 189.2 39.5 5.9e-39 134.4 15.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF77382.1 - 3.1e-48 163.8 1.2 6.9e-29 101.1 0.1 3.2 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGF77382.1 - 2.9e-10 40.0 7.8 0.027 13.9 0.1 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGF77382.1 - 1.1e-05 25.0 2.5 0.072 12.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF77382.1 - 1.3e-05 25.3 0.8 0.053 13.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGF77382.1 - 4.3e-05 23.5 0.2 0.57 9.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGF77382.1 - 0.00011 22.6 0.1 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGF77382.1 - 0.00049 20.1 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EGF77382.1 - 0.00066 18.8 0.3 0.46 9.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 EGF77382.1 - 0.00086 19.5 1.9 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 EGF77382.1 - 0.0023 17.2 0.4 0.28 10.3 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EGF77382.1 - 0.0028 17.6 0.3 2.5 8.0 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.6 EGF77382.1 - 0.0045 15.7 0.2 0.0084 14.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EGF77382.1 - 0.0045 16.4 0.5 0.66 9.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 EGF77382.1 - 0.0052 16.3 0.3 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 EGF77382.1 - 0.0056 16.7 2.4 0.47 10.5 0.3 2.5 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 EGF77382.1 - 0.0087 15.9 0.4 2.2 8.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGF77382.1 - 0.0097 15.6 0.4 3.9 7.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGF77382.1 - 0.011 16.3 2.2 3.8 7.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGF77382.1 - 0.017 15.4 5.4 1.1 9.6 0.5 3.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF77382.1 - 0.031 14.7 0.2 2 8.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 EGF77382.1 - 0.043 13.4 1.0 8 6.0 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EGF77382.1 - 0.053 13.1 0.2 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGF77382.1 - 0.056 13.2 0.2 7.4 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGF77382.1 - 0.085 12.9 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGF77382.1 - 0.11 12.7 0.8 18 5.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGF77382.1 - 0.13 12.2 1.7 14 5.6 0.1 3.2 3 0 0 3 3 3 0 NTPase DUF334 PF03904.13 EGF77382.1 - 0.14 11.6 7.4 3.8 7.0 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) S_4TM PF18159.1 EGF77382.1 - 0.8 8.9 10.5 0.027 13.8 1.3 2.5 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain RseC_MucC PF04246.12 EGF77382.1 - 8.3 6.4 9.6 14 5.6 1.5 3.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC WD40 PF00400.32 EGF77383.1 - 4.5e-41 138.1 14.4 6.7e-07 29.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77383.1 - 3.3e-14 53.0 0.6 0.0026 18.0 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF77383.1 - 6.5e-07 29.0 0.7 0.0021 17.4 0.0 2.6 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 EGF77383.1 - 5.5e-06 26.1 0.2 0.14 11.7 0.2 2.6 1 1 1 2 2 2 2 PQQ-like domain DUF5046 PF16465.5 EGF77383.1 - 1.1e-05 25.0 0.1 0.017 14.5 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) PQQ PF01011.21 EGF77383.1 - 4.8e-05 23.1 0.0 0.12 12.3 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat Ge1_WD40 PF16529.5 EGF77383.1 - 6e-05 22.2 0.2 0.38 9.7 0.0 4.0 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EGF77383.1 - 0.0012 18.9 0.2 3.3 7.8 0.0 3.8 3 2 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EGF77383.1 - 0.0095 14.6 4.0 1.2 7.7 0.0 4.2 1 1 4 5 5 5 1 Nucleoporin Nup120/160 Frtz PF11768.8 EGF77383.1 - 0.049 11.9 0.3 12 4.0 0.0 3.1 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 EGF77383.1 - 0.069 12.2 0.0 0.19 10.7 0.0 1.7 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain 5_nucleotid_C PF02872.18 EGF77384.1 - 8.2e-32 110.6 0.0 1.6e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGF77384.1 - 2.9e-12 47.5 0.2 4.5e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4407 PF14362.6 EGF77385.1 - 1.3 8.4 17.5 3.3 7.0 17.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Alpha-mann_mid PF09261.11 EGF77386.1 - 0.049 13.8 0.2 0.09 12.9 0.2 1.4 1 0 0 1 1 1 0 Alpha mannosidase middle domain Get5_bdg PF16843.5 EGF77386.1 - 0.075 12.5 0.4 0.83 9.2 0.0 2.7 3 1 1 4 4 4 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein DUF2524 PF10732.9 EGF77386.1 - 0.18 12.1 1.9 0.9 9.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Asp PF00026.23 EGF77387.1 - 1e-12 48.2 0.0 2.2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77387.1 - 1.9e-05 24.5 0.1 4.9e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal USP7_C2 PF14533.6 EGF77388.1 - 0.052 13.2 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Tom22 PF04281.13 EGF77388.1 - 1.5 8.6 4.2 0.58 9.9 1.4 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Pkinase PF00069.25 EGF77389.1 - 5.1e-12 45.7 0.0 1.9e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF77389.1 - 6.4e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF77389.1 - 0.0037 16.9 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF77389.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF77389.1 - 0.0079 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EGF77389.1 - 0.013 14.3 0.5 0.021 13.6 0.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF77389.1 - 0.015 14.6 0.1 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase FTA2 PF13095.6 EGF77389.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGF77389.1 - 0.059 12.9 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF77389.1 - 0.15 12.0 0.5 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DnaJ-X PF14308.6 EGF77390.1 - 2.5e-31 108.8 2.1 9.9e-30 103.6 2.1 2.3 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF77390.1 - 9.6e-24 83.3 0.9 2.4e-23 82.0 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain ING PF12998.7 EGF77390.1 - 0.16 12.6 1.4 0.46 11.1 0.1 2.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding SMAP PF15477.6 EGF77390.1 - 0.42 11.6 0.2 0.42 11.6 0.2 2.4 3 0 0 3 3 3 0 Small acidic protein family MetOD2 PF18548.1 EGF77391.1 - 0.021 14.9 1.0 0.048 13.8 1.0 1.7 1 0 0 1 1 1 0 Metanogen output domain 2 Erp_C PF06780.11 EGF77391.1 - 0.067 13.2 1.6 0.11 12.5 1.6 1.3 1 0 0 1 1 1 0 Erp protein C-terminus Scaffolding_pro PF11418.8 EGF77391.1 - 0.081 13.5 0.1 1 9.9 0.0 2.2 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4201 PF13870.6 EGF77392.1 - 0.0011 18.7 9.2 0.0016 18.2 9.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Cast PF10174.9 EGF77392.1 - 0.0016 16.8 2.9 0.0021 16.4 2.9 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Sporozoite_P67 PF05642.11 EGF77392.1 - 0.0031 15.7 1.8 0.0037 15.4 1.8 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen APG17 PF04108.12 EGF77392.1 - 0.0058 15.8 0.2 0.0066 15.6 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Phage_HK97_TLTM PF06120.11 EGF77392.1 - 0.0061 15.8 1.5 0.0081 15.4 1.5 1.2 1 0 0 1 1 1 1 Tail length tape measure protein HAP1_N PF04849.13 EGF77392.1 - 0.0088 15.3 3.6 0.012 14.8 3.6 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region FAM76 PF16046.5 EGF77392.1 - 0.009 15.4 2.9 0.012 15.0 2.9 1.2 1 0 0 1 1 1 1 FAM76 protein Macoilin PF09726.9 EGF77392.1 - 0.01 14.4 3.1 0.013 14.0 3.1 1.1 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 EGF77392.1 - 0.029 13.3 4.8 0.039 12.8 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EGF77392.1 - 0.1 13.2 2.9 0.14 12.8 2.3 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Calc_CGRP_IAPP PF00214.19 EGF77392.1 - 0.1 12.9 0.2 0.1 12.9 0.2 1.9 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family DivIC PF04977.15 EGF77392.1 - 0.11 12.3 0.9 0.21 11.4 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF1664 PF07889.12 EGF77392.1 - 0.14 12.2 1.5 0.22 11.5 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EGF77392.1 - 0.24 11.9 2.8 2.1 8.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 FliD_N PF02465.18 EGF77392.1 - 0.33 11.7 13.8 0.12 13.0 1.4 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.13 EGF77392.1 - 0.38 9.9 2.5 0.55 9.4 2.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 EGF77392.1 - 0.51 10.4 10.1 0.39 10.8 5.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4315 PF14193.6 EGF77392.1 - 0.54 10.3 4.5 1.2 9.2 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Arf PF00025.21 EGF77394.1 - 1.8e-18 66.6 0.0 2.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF77394.1 - 2.4e-06 27.8 0.0 0.00018 21.7 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGF77394.1 - 4.9e-05 23.4 0.0 5.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGF77394.1 - 0.042 13.5 0.0 0.22 11.1 0.0 1.9 1 1 0 1 1 1 0 Ras family DUF5027 PF16430.5 EGF77394.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5027) AAA PF00004.29 EGF77395.1 - 5.9e-13 49.4 0.0 1.9e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGF77395.1 - 8.7e-07 29.0 0.0 2.4e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGF77395.1 - 4.2e-06 26.8 0.0 1.5e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF77395.1 - 8.3e-06 26.1 0.4 0.00019 21.7 0.0 3.2 2 1 0 2 2 1 1 AAA domain Rad17 PF03215.15 EGF77395.1 - 2.3e-05 24.4 2.9 0.00012 22.1 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain RuvB_N PF05496.12 EGF77395.1 - 3.1e-05 23.8 0.0 0.0001 22.1 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGF77395.1 - 0.00022 21.4 0.0 0.00099 19.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF77395.1 - 0.00031 21.2 0.0 0.0069 16.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGF77395.1 - 0.0037 17.6 0.0 0.015 15.7 0.0 2.1 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EGF77395.1 - 0.0042 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EGF77395.1 - 0.0059 15.8 0.0 0.017 14.3 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.17 EGF77395.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 EGF77395.1 - 0.0076 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EGF77395.1 - 0.015 14.4 0.1 1.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 EGF77395.1 - 0.019 15.5 0.0 0.061 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF826 PF05696.11 EGF77395.1 - 0.033 14.3 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Zeta_toxin PF06414.12 EGF77395.1 - 0.043 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EGF77395.1 - 0.079 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EGF77395.1 - 0.11 12.4 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EGF77395.1 - 0.11 12.4 2.0 0.31 10.9 0.0 2.5 2 1 1 3 3 3 0 NTPase AAA_17 PF13207.6 EGF77395.1 - 0.12 12.9 0.9 0.67 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGF77395.1 - 0.14 11.7 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain KxDL PF10241.9 EGF77396.1 - 5.8e-18 64.9 1.0 6.8e-18 64.7 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein AAA-ATPase_like PF09820.9 EGF77396.1 - 0.046 13.1 0.1 0.052 13.0 0.1 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase FAM209 PF15206.6 EGF77396.1 - 0.055 13.3 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 FAM209 family MRP-S23 PF10484.9 EGF77396.1 - 0.065 13.5 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 Bud13 PF09736.9 EGF77397.1 - 6.3e-45 153.1 8.4 6.3e-45 153.1 8.4 2.7 3 2 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex RicinB_lectin_2 PF14200.6 EGF77399.1 - 1.6e-30 105.6 5.6 2.3e-15 57.1 0.2 3.9 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Glyco_hydr_30_2 PF14587.6 EGF77399.1 - 1.1e-26 94.4 2.5 5.1e-19 69.1 0.3 3.5 2 1 1 3 3 3 3 O-Glycosyl hydrolase family 30 Ricin_B_lectin PF00652.22 EGF77399.1 - 1.7e-08 34.8 1.2 1.7e-08 34.8 1.2 2.8 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Glyco_hydro_59 PF02057.15 EGF77399.1 - 1.9e-07 30.6 1.4 1.5e-05 24.4 3.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EGF77399.1 - 0.0076 16.4 0.2 0.019 15.2 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain SPA PF08616.10 EGF77400.1 - 2.4e-08 33.9 0.0 5.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis FMN_dh PF01070.18 EGF77401.1 - 2.4e-116 388.6 0.0 3e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGF77401.1 - 6.5e-22 77.5 0.0 1.4e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGF77401.1 - 3.3e-07 29.8 0.0 5.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGF77401.1 - 0.00061 18.9 0.0 0.0012 17.9 0.0 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGF77401.1 - 0.0066 15.9 0.2 0.01 15.3 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase GLYCAM-1 PF05242.11 EGF77402.1 - 0.12 12.5 4.7 0.39 10.8 4.7 1.8 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Trm112p PF03966.16 EGF77404.1 - 3.1e-12 46.9 0.0 3.6e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-primase PF09329.11 EGF77407.1 - 8.3e-13 47.9 2.4 5.5e-12 45.3 1.5 2.5 2 0 0 2 2 2 1 Primase zinc finger Arm PF00514.23 EGF77408.1 - 2e-55 183.3 24.4 9.5e-05 22.3 0.1 13.7 13 0 0 13 13 13 13 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGF77408.1 - 3e-17 62.8 16.9 0.00018 21.8 0.0 8.2 4 3 7 11 11 10 6 HEAT repeats Adaptin_N PF01602.20 EGF77408.1 - 2.7e-09 36.1 4.7 0.0023 16.6 2.7 4.0 2 2 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EGF77408.1 - 4.6e-09 36.1 5.7 0.0011 18.5 0.0 5.7 3 2 4 7 7 7 2 Armadillo-like V-ATPase_H_C PF11698.8 EGF77408.1 - 2.5e-08 34.0 4.5 0.14 12.3 0.0 6.9 2 1 5 8 8 8 1 V-ATPase subunit H HEAT PF02985.22 EGF77408.1 - 5.4e-08 32.4 14.1 0.33 11.3 0.1 8.3 9 0 0 9 9 8 3 HEAT repeat HEAT_EZ PF13513.6 EGF77408.1 - 1.3e-07 32.0 11.0 0.003 18.0 0.3 8.7 8 1 1 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 EGF77408.1 - 5e-07 29.9 5.7 0.099 12.7 0.0 5.0 4 2 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 EGF77408.1 - 3.4e-06 25.5 1.6 0.13 10.4 1.9 4.0 2 1 1 3 3 3 3 Kinesin-associated protein (KAP) Pes-10 PF07149.11 EGF77408.1 - 0.0023 17.0 0.5 0.016 14.3 0.5 2.3 2 0 0 2 2 2 1 Pes-10 DUF727 PF05303.12 EGF77408.1 - 0.0037 17.3 0.1 0.027 14.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF727) WAPL PF07814.13 EGF77408.1 - 0.0074 15.1 3.6 0.73 8.5 0.1 4.1 4 1 0 4 4 4 1 Wings apart-like protein regulation of heterochromatin UPF0147 PF03685.13 EGF77408.1 - 0.021 14.9 0.3 0.58 10.3 0.0 3.6 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0147) RasGEF_N_2 PF14663.6 EGF77408.1 - 0.033 14.6 7.4 24 5.4 0.8 5.9 5 2 2 7 7 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.9 EGF77408.1 - 0.038 14.0 0.5 5.1 7.2 0.1 4.6 5 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain RICTOR_N PF14664.6 EGF77408.1 - 0.047 12.7 4.3 0.67 8.9 0.3 3.6 2 2 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term V-ATPase_H_N PF03224.14 EGF77408.1 - 0.069 12.4 2.7 6.7 5.9 0.2 4.0 3 1 1 4 4 4 0 V-ATPase subunit H DUF1655 PF07868.11 EGF77408.1 - 0.2 11.7 0.2 0.52 10.4 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1655) adh_short_C2 PF13561.6 EGF77409.1 - 0.00012 21.7 0.3 0.0017 18.0 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase HNH_2 PF13391.6 EGF77410.1 - 8.2e-05 22.7 0.7 0.00028 21.0 0.1 2.4 2 1 0 2 2 2 1 HNH endonuclease Cytochrome_C7 PF14522.6 EGF77410.1 - 0.066 13.2 1.8 2.1 8.4 0.2 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF77410.1 - 0.072 12.8 4.6 1.4 8.8 0.3 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Pro_Al_protease PF02983.14 EGF77410.1 - 0.88 9.7 3.7 2 8.6 3.7 1.5 1 0 0 1 1 1 0 Alpha-lytic protease prodomain p450 PF00067.22 EGF77411.1 - 2.4e-77 260.7 0.1 2.9e-77 260.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ANAPC_CDC26 PF10471.9 EGF77413.1 - 8.4e-08 32.9 4.6 8.4e-08 32.9 4.6 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 His_Phos_2 PF00328.22 EGF77414.1 - 2.7e-20 73.1 0.0 2.2e-13 50.4 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) NAD_binding_6 PF08030.12 EGF77415.1 - 2.2e-13 50.6 0.0 3.5e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGF77415.1 - 5.2e-13 49.2 8.5 5.2e-13 49.2 8.5 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGF77415.1 - 1.8e-08 34.4 0.1 4.4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EGF77415.1 - 6.2e-06 26.8 0.0 0.00016 22.3 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Pam17 PF08566.10 EGF77415.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Use1 PF09753.9 EGF77416.1 - 3.8e-14 53.0 7.6 6.2e-14 52.3 7.6 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Baculo_11_kDa PF06143.11 EGF77416.1 - 0.11 12.1 0.2 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family CNH PF00780.22 EGF77417.1 - 3.3e-65 220.4 0.0 7.4e-65 219.3 0.0 1.5 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGF77417.1 - 1.4e-39 136.2 0.8 6.2e-39 134.1 0.9 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 EGF77417.1 - 3.2e-22 79.1 0.0 6.7e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 EGF77417.1 - 6.1e-12 45.4 0.0 1.6e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 EGF77417.1 - 0.00028 21.4 0.0 0.00097 19.6 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EGF77417.1 - 0.00077 19.3 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 EGF77417.1 - 0.0023 17.7 0.0 0.0079 16.0 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain COX7C PF02935.16 EGF77418.1 - 0.00077 19.7 3.0 0.0011 19.2 3.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc FAM176 PF14851.6 EGF77419.1 - 0.045 13.4 1.0 0.27 10.9 0.7 2.2 2 0 0 2 2 2 0 FAM176 family TRP PF06011.12 EGF77419.1 - 0.075 11.8 21.0 0.033 12.9 17.8 2.0 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel FPRL1_inhibitor PF16104.5 EGF77419.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein TMEM154 PF15102.6 EGF77419.1 - 4.2 7.3 10.5 7.4 6.5 3.3 3.0 2 0 0 2 2 2 0 TMEM154 protein family Calreticulin PF00262.18 EGF77420.1 - 6.8e-79 265.4 12.8 5e-59 200.0 2.4 2.1 1 1 1 2 2 2 2 Calreticulin family SpoIIE PF07228.12 EGF77421.1 - 3.6e-15 56.4 0.0 4.7e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGF77421.1 - 2.8e-10 40.3 0.0 4.2e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGF77421.1 - 6.9e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C AAA PF00004.29 EGF77422.1 - 8.8e-37 126.5 0.0 1.2e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF77422.1 - 1.6e-06 28.6 0.2 0.0002 21.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGF77422.1 - 5.9e-06 26.1 0.0 1.2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EGF77422.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EGF77422.1 - 3e-05 24.6 0.0 4.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGF77422.1 - 3.9e-05 23.7 0.1 0.00022 21.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGF77422.1 - 6.2e-05 22.4 0.0 9.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EGF77422.1 - 0.00011 22.3 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGF77422.1 - 0.00012 22.4 0.1 0.021 15.1 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_33 PF13671.6 EGF77422.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGF77422.1 - 0.00037 20.2 0.1 0.0081 15.9 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 EGF77422.1 - 0.00083 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGF77422.1 - 0.001 19.5 0.0 0.0015 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF77422.1 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGF77422.1 - 0.0031 17.2 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 EGF77422.1 - 0.0044 17.1 0.0 0.017 15.3 0.0 1.8 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 EGF77422.1 - 0.0053 16.3 0.0 0.011 15.2 0.0 1.7 2 1 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGF77422.1 - 0.0054 16.1 0.2 0.013 14.9 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGF77422.1 - 0.0075 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TsaE PF02367.17 EGF77422.1 - 0.028 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGF77422.1 - 0.029 14.2 0.0 0.037 13.9 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGF77422.1 - 0.03 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EGF77422.1 - 0.036 14.0 0.1 2 8.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EGF77422.1 - 0.038 14.4 0.0 0.048 14.0 0.0 1.4 1 1 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 EGF77422.1 - 0.046 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IPT PF01745.16 EGF77422.1 - 0.048 13.1 0.0 0.091 12.1 0.0 1.5 1 1 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.16 EGF77422.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EGF77422.1 - 0.073 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 EGF77422.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGF77422.1 - 0.14 12.5 0.2 0.27 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGF77422.1 - 0.19 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain GtrA PF04138.14 EGF77423.1 - 0.11 12.7 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 GtrA-like protein DUF2428 PF10350.9 EGF77424.1 - 2.9e-09 36.6 0.9 7.2e-09 35.3 0.9 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) WD40 PF00400.32 EGF77425.1 - 1.5e-51 171.2 15.5 1e-09 38.8 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EGF77425.1 - 1.9e-42 144.6 1.1 3.3e-42 143.8 1.1 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EGF77425.1 - 2.4e-14 53.4 0.0 0.029 14.7 0.0 6.0 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF77425.1 - 3.5e-05 23.3 0.0 1.2 8.4 0.0 4.3 3 1 2 5 5 5 1 WD40-like domain Nup160 PF11715.8 EGF77425.1 - 0.0011 17.7 1.7 0.11 11.1 0.0 3.1 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF77425.1 - 0.0059 15.6 0.1 2.9 6.8 0.0 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 EGF77425.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 LisH RabGAP-TBC PF00566.18 EGF77426.1 - 1e-47 162.6 0.0 2.6e-47 161.3 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 EGF77426.1 - 1.3e-15 57.3 1.8 1e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_6 PF13405.6 EGF77426.1 - 3.1e-06 26.7 1.2 1.1 9.4 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGF77426.1 - 0.0021 18.5 8.2 0.6 10.6 0.4 4.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF77426.1 - 0.036 13.6 9.1 0.68 9.6 0.0 4.2 3 0 0 3 3 3 0 EF hand NPA PF16469.5 EGF77426.1 - 0.69 10.5 4.4 1.4 9.5 3.5 2.1 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 EF-hand_8 PF13833.6 EGF77426.1 - 5.4 6.9 7.5 0.95 9.4 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain pair CLAMP PF14769.6 EGF77427.1 - 9.7e-24 83.7 4.5 1.7e-23 82.9 4.5 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Ribosomal_L19e PF01280.20 EGF77428.1 - 2e-61 206.3 8.0 2e-61 206.3 8.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Lant_dehydr_C PF14028.6 EGF77428.1 - 0.0023 17.6 0.5 0.0023 17.6 0.5 1.8 1 1 1 2 2 2 1 Lantibiotic biosynthesis dehydratase C-term B-block_TFIIIC PF04182.12 EGF77428.1 - 0.029 14.5 0.1 4.3 7.6 0.1 2.6 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC WD40 PF00400.32 EGF77429.1 - 3.8e-21 75.0 22.9 1.5e-07 31.9 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77429.1 - 2.9e-07 30.7 0.7 0.5 10.7 0.0 5.5 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EGF77429.1 - 1.1e-05 25.2 0.1 2.5e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF77429.1 - 7.4e-05 22.5 0.0 0.0002 21.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain KTSC PF13619.6 EGF77429.1 - 0.015 15.1 0.3 0.35 10.7 0.1 2.5 2 0 0 2 2 2 0 KTSC domain PSP1 PF04468.12 EGF77429.1 - 0.042 14.1 2.6 0.22 11.8 0.1 2.4 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Yop-YscD_cpl PF16697.5 EGF77429.1 - 0.11 12.8 0.1 0.98 9.8 0.0 2.2 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Ribosomal_S13 PF00416.22 EGF77430.1 - 1.4e-56 190.4 4.9 1.6e-56 190.2 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 EGF77430.1 - 0.063 13.5 0.1 0.19 12.0 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif H2TH PF06831.14 EGF77430.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain PP28 PF10252.9 EGF77430.1 - 0.23 12.0 1.4 0.45 11.0 1.4 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 ERCC3_RAD25_C PF16203.5 EGF77431.1 - 2.5e-117 390.5 0.5 3.7e-117 389.9 0.5 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGF77431.1 - 1e-34 119.4 0.0 2.5e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF77431.1 - 1.1e-12 48.3 0.0 2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF77431.1 - 2.2e-10 40.9 0.1 4.6e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGF77431.1 - 6.5e-06 25.1 0.0 9.3e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF918 PF06033.11 EGF77433.1 - 0.0041 17.1 0.1 0.0079 16.2 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) Peptidase_C97 PF05903.14 EGF77437.1 - 0.0004 20.2 0.0 0.00083 19.2 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain RRT14 PF17075.5 EGF77437.1 - 0.031 14.4 0.6 0.052 13.7 0.6 1.3 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 LRR_8 PF13855.6 EGF77438.1 - 3.4e-07 29.9 1.4 6.1e-07 29.1 1.4 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGF77438.1 - 0.00015 22.1 1.6 0.00022 21.5 0.7 1.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF77438.1 - 0.22 12.2 3.2 5.2 8.0 0.2 2.9 3 1 0 3 3 3 0 Leucine Rich Repeat PUF PF00806.19 EGF77439.1 - 1.4e-70 229.1 7.6 2.2e-08 33.4 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 EGF77439.1 - 0.0045 16.8 0.8 7.1 6.5 0.0 4.8 5 1 1 6 6 6 1 Single Cache domain 2 CLPTM1 PF05602.12 EGF77440.1 - 6.6e-126 420.8 7.7 8.6e-126 420.4 7.7 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGF77440.1 - 0.00013 21.7 0.4 0.29 10.9 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EGF77440.1 - 0.015 15.3 0.2 0.015 15.3 0.2 3.0 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF1097 PF06496.11 EGF77440.1 - 0.025 14.7 1.0 0.062 13.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) DUF1761 PF08570.10 EGF77440.1 - 0.099 12.9 4.2 0.27 11.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) MlaE PF02405.16 EGF77440.1 - 0.22 11.2 2.2 0.44 10.2 0.5 2.0 2 0 0 2 2 2 0 Permease MlaE DHFR_1 PF00186.19 EGF77441.1 - 4.1e-27 94.9 0.0 9.4e-17 61.2 0.0 2.8 2 1 0 2 2 2 2 Dihydrofolate reductase Ost5 PF05251.12 EGF77442.1 - 1.2e-22 79.9 8.1 2.2e-22 79.1 8.1 1.4 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 TRSP PF12500.8 EGF77442.1 - 0.21 11.5 0.0 0.71 9.8 0.0 1.7 2 0 0 2 2 2 0 TRSP domain C terminus to PRTase_2 RNA_pol_Rpb6 PF01192.22 EGF77443.1 - 1.9e-16 59.7 0.0 2.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-CCCH_2 PF14608.6 EGF77444.1 - 0.00081 19.8 20.7 0.0026 18.1 4.9 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 EGF77444.1 - 0.26 11.4 6.5 4 7.6 0.4 2.8 2 0 0 2 2 2 0 Zinc finger domain CHCH PF06747.13 EGF77445.1 - 0.005 17.0 6.0 0.014 15.5 6.1 1.7 1 1 1 2 2 2 2 CHCH domain CX9C PF16860.5 EGF77445.1 - 0.082 12.9 3.0 3.3 7.8 0.5 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1482 PF07358.11 EGF77445.1 - 0.12 12.3 1.8 3.4 7.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1482) Methyltransf_31 PF13847.6 EGF77446.1 - 5e-07 29.6 0.0 3e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF77446.1 - 1e-06 28.4 0.0 0.0039 16.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 EGF77446.1 - 3.1e-05 24.6 0.1 0.00034 21.3 0.1 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF77446.1 - 0.0043 17.8 0.1 0.065 14.0 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 EGF77446.1 - 0.0093 16.5 0.1 0.034 14.7 0.0 2.0 2 0 0 2 2 2 1 PrmC N-terminal domain Ubie_methyltran PF01209.18 EGF77446.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Eco57I PF07669.11 EGF77446.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase PrmA PF06325.13 EGF77446.1 - 0.16 11.4 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pantoate_transf PF02548.15 EGF77447.1 - 1.6e-107 358.7 0.1 2e-107 358.4 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGF77447.1 - 6.3e-06 25.8 0.0 9.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase YceG PF02618.16 EGF77447.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 YceG-like family LKAAEAR PF15478.6 EGF77448.1 - 2.7e-08 34.2 3.4 2.7e-08 34.2 3.4 2.0 2 1 0 2 2 2 1 Family of unknown function with LKAAEAR motif CHCH PF06747.13 EGF77449.1 - 0.0066 16.6 6.1 0.018 15.2 6.2 1.6 1 1 1 2 2 2 2 CHCH domain DUF1482 PF07358.11 EGF77449.1 - 0.12 12.3 1.3 3.7 7.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1482) Ribonuc_L-PSP PF01042.21 EGF77450.1 - 7e-45 151.9 0.3 7.8e-45 151.8 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 EGF77450.1 - 0.077 13.1 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease SH3_9 PF14604.6 EGF77451.1 - 8.9e-09 35.1 0.0 2.3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGF77451.1 - 6.7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 EGF77451.1 - 0.00085 18.8 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 EGF77451.1 - 0.0012 19.0 0.2 0.0022 18.1 0.2 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EGF77451.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 EGF77451.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EGF77451.1 - 0.021 14.6 0.4 0.042 13.6 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Amnionless PF14828.6 EGF77451.1 - 0.027 13.3 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Amnionless Sigma_reg_N PF13800.6 EGF77451.1 - 0.04 14.2 0.1 0.073 13.4 0.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SKG6 PF08693.10 EGF77451.1 - 0.1 12.0 3.1 0.27 10.7 3.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF508 PF04370.12 EGF77451.1 - 2.8 7.7 7.8 5.3 6.8 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF508) FMN_red PF03358.15 EGF77452.1 - 2.9e-08 33.6 0.0 4.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Tyrosinase PF00264.20 EGF77453.1 - 1.1e-35 124.0 3.7 3e-35 122.5 3.7 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 EGF77453.1 - 0.02 15.5 0.2 0.059 14.0 0.0 1.8 2 0 0 2 2 2 0 HMG-box domain Fungal_trans PF04082.18 EGF77454.1 - 1.4e-20 73.5 1.0 2e-20 73.0 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF77454.1 - 5.9e-06 26.3 13.5 5.9e-06 26.3 13.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EGF77455.1 - 4.5e-07 29.9 10.4 8.6e-07 29.0 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGF77455.1 - 1e-06 28.0 0.3 2.5e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4983 PF16356.5 EGF77455.1 - 0.13 13.1 0.1 0.51 11.2 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4983) Zn_clus PF00172.18 EGF77456.1 - 4.2e-08 33.2 11.4 7.2e-08 32.4 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sas10_Utp3 PF04000.15 EGF77457.1 - 5.8e-10 39.7 1.8 1.6e-09 38.3 1.8 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Nif11 PF07862.11 EGF77457.1 - 0.073 13.4 1.0 8.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Nif11 domain HLH PF00010.26 EGF77458.1 - 4.6e-13 48.9 0.6 8.3e-13 48.1 0.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ada_Zn_binding PF02805.16 EGF77458.1 - 0.027 14.5 1.5 0.041 13.9 0.1 2.0 2 0 0 2 2 2 0 Metal binding domain of Ada CAF1 PF04857.20 EGF77459.1 - 9.4e-83 278.0 0.5 1.3e-82 277.5 0.5 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 EGF77459.1 - 1.4e-13 50.7 0.4 6.5e-12 45.3 0.0 3.1 3 0 0 3 3 3 1 RNA binding domain NCBP3 PF10309.9 EGF77459.1 - 0.0091 15.8 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DUF327 PF03885.13 EGF77459.1 - 0.0094 15.9 0.4 0.027 14.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF327) DNA_pol_A_exo1 PF01612.20 EGF77459.1 - 0.046 13.4 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 3'-5' exonuclease MFS_1 PF07690.16 EGF77460.1 - 9.8e-08 31.3 15.3 1.3e-07 30.9 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGF77460.1 - 1.2e-07 30.6 16.3 1.6e-06 26.9 6.9 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein SPP PF06550.11 EGF77460.1 - 0.0083 15.6 5.5 0.011 15.3 5.5 1.2 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease DUF2269 PF10027.9 EGF77460.1 - 0.47 10.5 8.8 0.055 13.5 3.1 2.2 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF2530 PF10745.9 EGF77460.1 - 2.2 8.6 5.6 0.76 10.1 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Pkinase PF00069.25 EGF77461.1 - 2.1e-68 230.6 0.0 2.6e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77461.1 - 1.9e-33 115.8 0.0 2.6e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77461.1 - 0.0021 17.4 0.0 0.0034 16.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF77461.1 - 0.041 12.8 0.4 0.068 12.1 0.4 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Apt1 PF10351.9 EGF77461.1 - 0.28 10.0 4.7 0.37 9.6 4.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 EGF77461.1 - 1.2 7.4 4.2 1.7 6.9 4.2 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EGF77461.1 - 3.6 6.0 7.6 4.5 5.7 7.6 1.1 1 0 0 1 1 1 0 Macoilin family Chitin_synth_2 PF03142.15 EGF77462.1 - 2.2e-206 686.6 0.8 2.5e-206 686.4 0.8 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGF77462.1 - 5.5e-10 39.5 5.1 1.7e-09 37.9 5.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF77462.1 - 2.5e-09 37.4 0.0 1.4e-08 34.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGF77462.1 - 0.00044 20.1 0.0 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGF77462.1 - 0.045 13.2 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 TssN PF17555.2 EGF77462.1 - 1.2 8.5 14.6 0.42 9.9 8.6 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF1600 PF07667.11 EGF77462.1 - 1.2 9.4 6.9 1 9.5 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) SAP18 PF06487.12 EGF77463.1 - 1.3e-26 93.5 0.0 3.2e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Ribosomal_L3 PF00297.22 EGF77463.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L3 BNIP2 PF12496.8 EGF77463.1 - 0.17 12.3 3.7 0.29 11.6 3.7 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CAF1 PF04857.20 EGF77464.1 - 1e-59 202.3 0.0 6.3e-29 101.2 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease GCP_C_terminal PF04130.13 EGF77465.1 - 1.2e-21 77.5 4.1 2.8e-21 76.3 2.6 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGF77465.1 - 2.8e-15 56.7 2.9 5.3e-15 55.8 2.6 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal hDGE_amylase PF14701.6 EGF77466.1 - 7.9e-158 526.1 1.0 1e-157 525.8 1.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGF77466.1 - 2.6e-103 345.9 0.0 4.2e-103 345.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGF77466.1 - 1.4e-67 228.0 0.0 2.2e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Fungal_trans PF04082.18 EGF77467.1 - 1.8e-22 79.6 1.5 3.2e-22 78.8 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF77467.1 - 3.2e-10 40.0 8.9 8.5e-10 38.6 8.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MciZ PF13072.6 EGF77467.1 - 0.17 11.7 0.2 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ Fungal_trans PF04082.18 EGF77468.1 - 3.5e-15 55.8 0.7 3.5e-15 55.8 0.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF77468.1 - 4.6e-07 29.8 14.2 1.2e-06 28.5 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2268 PF10026.9 EGF77468.1 - 0.087 12.4 0.5 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CH_2 PF06294.11 EGF77469.1 - 1.1e-33 115.2 0.0 2.6e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGF77469.1 - 1.1e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain 4PPT_N PF17837.1 EGF77470.1 - 0.062 13.4 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain SAGA-Tad1 PF12767.7 EGF77475.1 - 6.7e-32 111.1 0.0 4.1e-31 108.5 0.0 2.0 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Chitin_bind_1 PF00187.19 EGF77476.1 - 2.3e-85 280.8 371.8 2.2e-07 31.2 19.1 15.5 15 0 0 15 15 15 15 Chitin recognition protein SET PF00856.28 EGF77477.1 - 2.5e-20 73.6 0.3 1.3e-19 71.2 0.3 2.0 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 EGF77477.1 - 0.08 13.6 9.2 0.086 13.5 7.5 1.8 2 0 0 2 2 2 0 Pre-SET motif Chitin_synth_2 PF03142.15 EGF77478.1 - 4.4e-250 830.8 0.0 5.2e-250 830.5 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGF77478.1 - 7.8e-14 52.1 0.0 3.6e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF77478.1 - 2.1e-12 47.4 11.1 1.2e-11 44.9 11.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGF77478.1 - 1.1e-05 24.9 0.2 0.0063 16.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF77478.1 - 0.0011 18.8 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Fungal_trans PF04082.18 EGF77479.1 - 5.6e-19 68.2 0.8 1.1e-18 67.2 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF77479.1 - 5.4e-09 36.0 4.7 9.5e-09 35.2 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 5_nucleotid_C PF02872.18 EGF77480.1 - 7.5e-39 133.5 0.1 1.3e-38 132.7 0.1 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGF77480.1 - 6.1e-10 39.9 0.1 1.2e-09 39.0 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Chitin_synth_2 PF03142.15 EGF77481.1 - 6.7e-233 774.1 1.3 9.7e-233 773.5 1.3 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGF77481.1 - 2.1e-12 47.4 0.1 4.6e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF77481.1 - 3.3e-12 46.7 10.4 3.3e-12 46.7 10.4 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGF77481.1 - 2.7e-06 27.0 0.0 1.1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF77481.1 - 0.0023 17.8 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 IstB_IS21 PF01695.17 EGF77482.1 - 0.029 14.1 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4246 PF14033.6 EGF77483.1 - 1.9e-93 314.1 0.0 2.9e-93 313.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) ATG16 PF08614.11 EGF77485.1 - 2.1 8.6 5.2 13 6.0 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MSA-2c PF12238.8 EGF77485.1 - 2.4 8.1 9.6 0.18 11.8 4.2 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c zf-RING_2 PF13639.6 EGF77486.1 - 5.6e-09 36.2 4.9 1.1e-08 35.2 4.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF77486.1 - 1.4e-05 24.8 4.6 2.9e-05 23.8 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF77486.1 - 0.00011 21.9 4.0 0.00011 21.9 4.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF77486.1 - 0.00011 21.9 4.2 0.00023 21.0 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF77486.1 - 0.00028 21.1 6.3 0.0014 18.9 6.3 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EGF77486.1 - 0.0047 16.5 2.9 0.009 15.6 2.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 EGF77486.1 - 0.087 12.7 5.6 0.19 11.7 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 EGF77486.1 - 0.099 12.6 3.3 0.18 11.8 3.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF77486.1 - 0.56 10.3 8.0 0.15 12.1 4.6 1.8 2 0 0 2 2 2 0 RING-type zinc-finger CCDC50_N PF15295.6 EGF77486.1 - 1.1 9.5 7.4 1.8 8.7 7.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus FANCL_C PF11793.8 EGF77486.1 - 1.4 9.2 3.7 3 8.1 3.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGF77486.1 - 2.4 8.5 5.1 3.5 8.0 3.5 2.0 2 0 0 2 2 2 0 RING-like domain Gly_transf_sug PF04488.15 EGF77487.1 - 2e-15 57.2 0.2 5.4e-15 55.8 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EGF77487.1 - 0.031 13.6 0.3 0.046 13.0 0.3 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain UPRTase PF14681.6 EGF77487.1 - 0.039 13.4 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Caps_synth PF05704.12 EGF77487.1 - 0.055 12.8 1.0 5.2 6.4 0.0 2.6 3 0 0 3 3 3 0 Capsular polysaccharide synthesis protein DUF3021 PF11457.8 EGF77487.1 - 0.2 12.0 2.5 0.43 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) zf-CCCH_2 PF14608.6 EGF77488.1 - 2e-13 50.2 53.9 0.0002 21.7 6.2 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGF77488.1 - 5.8 7.2 12.1 31 4.8 1.3 4.4 3 1 1 4 4 4 0 Zinc-finger containing family PhzC-PhzF PF02567.16 EGF77490.1 - 7.3e-65 219.2 0.1 8.2e-65 219.1 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pantoate_transf PF02548.15 EGF77491.1 - 6.8e-102 340.3 0.1 8.4e-102 340.0 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGF77491.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase YceG PF02618.16 EGF77491.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 YceG-like family Lipase_3 PF01764.25 EGF77492.1 - 1.1e-38 132.3 0.0 2.2e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 EGF77492.1 - 1.3e-05 25.2 1.3 3.3e-05 23.9 0.2 2.0 1 1 1 2 2 2 1 Cutinase Hydrolase_4 PF12146.8 EGF77492.1 - 0.00061 19.1 0.1 0.0013 18.0 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EGF77492.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 EGF77492.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 EGF77492.1 - 0.023 15.3 0.0 0.031 14.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EGF77492.1 - 0.034 13.7 0.0 0.089 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EGF77492.1 - 0.05 13.4 0.2 1.4 8.7 0.0 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase family HLH PF00010.26 EGF77493.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Zn_clus PF00172.18 EGF77494.1 - 7.2e-11 42.0 11.8 9.2e-11 41.7 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAF1_subA PF14929.6 EGF77495.1 - 0.0029 17.1 0.3 0.0032 16.9 0.3 1.0 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A DnaJ PF00226.31 EGF77496.1 - 1.9e-23 82.4 1.0 4e-23 81.3 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain TetR_C_17 PF17922.1 EGF77496.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 EGF77497.1 - 5.4e-12 45.6 0.0 2e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF77497.1 - 7.2e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF77497.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF77497.1 - 0.0082 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF77497.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF77497.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF77497.1 - 0.021 13.6 0.4 0.029 13.2 0.4 1.3 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF77497.1 - 0.025 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF77497.1 - 0.081 12.4 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF77497.1 - 0.18 11.7 0.2 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins HNH_2 PF13391.6 EGF77498.1 - 2.5e-05 24.3 0.1 0.00067 19.7 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease DASH_Duo1 PF08651.10 EGF77498.1 - 0.11 12.2 1.5 0.28 11.0 1.5 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 Paired_CXXCH_1 PF09699.10 EGF77498.1 - 0.51 10.1 2.4 5.7 6.8 0.2 2.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) RNA_pol_Rpb1_2 PF00623.20 EGF77499.1 - 2.4e-10 40.9 0.0 4.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 DUF4246 PF14033.6 EGF77501.1 - 6.6e-84 282.6 0.3 8.3e-84 282.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Adaptin_N PF01602.20 EGF77502.1 - 0.0042 15.7 0.1 0.0062 15.2 0.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region AAA_16 PF13191.6 EGF77503.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EGF77503.1 - 0.059 13.7 0.2 0.37 11.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain HNH_2 PF13391.6 EGF77504.1 - 2e-05 24.7 0.2 0.00055 20.0 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease Cytochrome_C7 PF14522.6 EGF77504.1 - 0.28 11.2 2.3 4.2 7.4 0.4 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF77504.1 - 1.1 9.0 4.8 5.6 6.8 0.2 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF2437 PF10370.9 EGF77505.1 - 0.2 12.6 0.0 0.28 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) DUF2564 PF10819.8 EGF77507.1 - 0.29 11.5 2.3 0.37 11.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Mito_carr PF00153.27 EGF77508.1 - 4.6e-48 161.1 0.1 2.1e-21 75.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF77508.1 - 0.13 11.4 0.3 0.93 8.6 0.0 2.0 1 1 1 2 2 2 0 Gammaproteobacterial serine protease ATP_bind_1 PF03029.17 EGF77509.1 - 2e-77 260.2 1.0 2.9e-77 259.7 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGF77509.1 - 7.3e-09 35.4 0.0 9.1e-08 31.9 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGF77509.1 - 1.2e-05 24.9 0.1 0.00057 19.4 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B cobW PF02492.19 EGF77509.1 - 0.00022 20.9 0.1 0.0021 17.7 0.1 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGF77509.1 - 0.00041 20.4 0.0 0.0037 17.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EGF77509.1 - 0.00042 20.3 0.1 0.00079 19.4 0.0 1.6 2 0 0 2 2 1 1 NACHT domain AAA_30 PF13604.6 EGF77509.1 - 0.00084 19.1 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF77509.1 - 0.00094 19.1 0.0 3.5 7.5 0.0 3.3 3 1 0 3 3 3 2 RsgA GTPase CbiA PF01656.23 EGF77509.1 - 0.0017 18.4 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EGF77509.1 - 0.0021 17.1 0.0 0.71 8.8 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 EGF77509.1 - 0.0028 17.4 0.2 0.14 11.9 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGF77509.1 - 0.0028 18.1 0.0 0.0062 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 EGF77509.1 - 0.0032 17.0 0.4 0.99 8.8 0.0 3.2 3 1 0 3 3 3 1 ADP-ribosylation factor family NB-ARC PF00931.22 EGF77509.1 - 0.0041 16.3 0.0 0.0099 15.1 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 EGF77509.1 - 0.0055 17.0 0.1 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 EGF77509.1 - 0.0056 16.3 0.0 0.74 9.4 0.0 2.7 2 1 0 2 2 2 1 Ras family AAA_19 PF13245.6 EGF77509.1 - 0.0057 17.0 0.1 0.016 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF77509.1 - 0.0061 16.7 0.1 0.017 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGF77509.1 - 0.01 15.5 0.1 0.085 12.5 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EGF77509.1 - 0.011 15.7 0.3 0.29 11.0 0.1 2.4 3 0 0 3 3 2 0 NTPase AAA_23 PF13476.6 EGF77509.1 - 0.012 16.1 0.2 3.5 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGF77509.1 - 0.05 13.8 0.0 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGF77509.1 - 0.05 13.3 0.4 0.23 11.1 0.4 2.2 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 EGF77509.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 EGF77509.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EGF77509.1 - 0.12 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EGF77509.1 - 0.12 12.9 0.2 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EGF77509.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase FAM178 PF14816.6 EGF77509.1 - 2.3 7.1 5.6 3.7 6.4 5.6 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 Pkinase PF00069.25 EGF77511.1 - 2.3e-72 243.5 0.0 3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77511.1 - 1.7e-36 125.8 0.0 2.6e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77511.1 - 0.0021 17.4 0.0 0.0049 16.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF77511.1 - 3.3 6.5 4.9 0.99 8.3 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 EGF77512.1 - 4.9e-51 173.6 0.0 5.3e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77512.1 - 8.9e-40 136.6 0.0 1.1e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77512.1 - 0.00036 19.4 0.0 0.00047 19.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF77512.1 - 0.039 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGF77512.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dabb PF07876.12 EGF77513.1 - 3.5e-18 66.0 0.0 3.9e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain SH3_9 PF14604.6 EGF77515.1 - 1.6e-07 31.1 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF77515.1 - 0.00041 19.9 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Stevor PF17410.2 EGF77515.1 - 0.015 14.9 0.3 0.043 13.3 0.1 1.8 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame APG6_N PF17675.1 EGF77515.1 - 0.26 11.8 14.5 0.56 10.7 14.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region EphA2_TM PF14575.6 EGF77515.1 - 0.78 10.7 2.4 1 10.3 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CDC24 PF06395.11 EGF77516.1 - 5.4e-25 87.5 0.1 1.1e-24 86.5 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 EGF77516.1 - 2.2e-20 73.2 0.1 4.4e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 EGF77516.1 - 9.5e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain RhoGEF PF00621.20 EGF77516.1 - 5.8e-09 36.4 1.6 1.2e-08 35.4 1.6 1.6 1 0 0 1 1 1 1 RhoGEF domain CwfJ_C_1 PF04677.15 EGF77518.1 - 3.2e-23 81.9 1.3 1.1e-22 80.2 1.3 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 EGF77518.1 - 6.4e-17 61.0 18.2 4.4e-10 39.2 5.8 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 EGF77518.1 - 1.2e-08 34.6 10.5 8.7e-05 22.4 2.4 2.7 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 EGF77518.1 - 1.6e-06 28.9 0.0 4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 EGF77518.1 - 0.037 14.7 0.6 0.11 13.2 0.4 2.0 2 0 0 2 2 2 0 HIT domain zf-CCHC_5 PF14787.6 EGF77518.1 - 0.057 13.1 2.0 0.14 11.9 2.0 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Zn_ribbon_SprT PF17283.2 EGF77518.1 - 0.45 10.5 5.1 5.7 6.9 1.6 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-CCHC_4 PF14392.6 EGF77518.1 - 2.4 8.0 7.4 0.24 11.2 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGF77518.1 - 3.5 7.7 12.2 1.3 9.1 2.6 3.0 3 0 0 3 3 3 0 Zinc knuckle CorA PF01544.18 EGF77519.1 - 2e-47 161.9 1.5 2.4e-47 161.7 1.5 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Dehydratase_hem PF13816.6 EGF77519.1 - 0.045 13.2 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase 5_nucleotid_C PF02872.18 EGF77520.1 - 6.6e-32 110.9 0.0 1.3e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGF77520.1 - 4.8e-12 46.8 0.2 7.3e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M36 PF02128.15 EGF77521.1 - 4.8e-119 397.8 3.4 1e-61 209.2 0.3 2.1 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF77521.1 - 7.7e-10 38.4 1.8 1.8e-09 37.3 1.8 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EGF77521.1 - 0.0011 19.5 0.2 0.0022 18.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain CNDH2_M PF16869.5 EGF77522.1 - 0.014 16.1 2.0 0.014 16.1 2.0 2.3 2 1 1 3 3 3 0 PF16858 Terminase_4 PF05119.12 EGF77522.1 - 0.031 14.7 0.6 0.11 12.9 0.8 1.8 2 0 0 2 2 2 0 Phage terminase, small subunit FapA PF03961.13 EGF77522.1 - 1.3 7.5 4.1 1.7 7.2 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cmyb_C PF09316.10 EGF77523.1 - 0.041 13.6 0.4 0.041 13.6 0.4 2.2 2 2 0 2 2 2 0 C-myb, C-terminal DUF2201_N PF13203.6 EGF77523.1 - 3.2 7.3 6.8 2.3 7.7 4.9 1.6 1 1 0 1 1 1 0 Putative metallopeptidase domain SRAP PF02586.14 EGF77524.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 SOS response associated peptidase (SRAP) Asp PF00026.23 EGF77527.1 - 2.6e-14 53.4 0.0 4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77527.1 - 0.0009 19.0 0.1 0.0075 16.1 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Diacid_rec PF05651.13 EGF77527.1 - 0.12 12.0 0.1 0.32 10.7 0.1 1.6 2 0 0 2 2 2 0 Putative sugar diacid recognition Fe-ADH PF00465.19 EGF77528.1 - 0.16 10.7 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Zn_peptidase PF04228.13 EGF77529.1 - 0.038 13.5 1.5 0.061 12.8 1.0 1.5 1 1 0 1 1 1 0 Putative neutral zinc metallopeptidase BET PF17035.5 EGF77529.1 - 0.19 11.9 3.0 3.4 7.9 0.5 3.2 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation DUF1539 PF07560.11 EGF77529.1 - 0.94 9.6 12.0 9.4 6.3 0.3 3.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1539) DUF4246 PF14033.6 EGF77530.1 - 1.6e-79 268.2 0.3 2e-79 267.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Spc7 PF08317.11 EGF77531.1 - 0.011 14.6 0.1 0.011 14.6 0.1 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 EGF77531.1 - 0.058 13.2 0.5 0.23 11.2 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator SelA PF03841.13 EGF77531.1 - 0.065 12.2 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase U79_P34 PF03064.16 EGF77531.1 - 0.49 9.7 13.2 0.87 8.9 13.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 G-patch PF01585.23 EGF77533.1 - 2.1e-16 59.5 0.5 4.6e-16 58.4 0.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF77533.1 - 2.6e-09 37.0 0.3 1.3e-08 34.8 0.1 2.3 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 EGF77533.1 - 0.055 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 R3H domain Chromo_shadow PF01393.19 EGF77534.1 - 1.9e-20 72.7 2.8 3.5e-18 65.4 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGF77534.1 - 1.3e-11 44.2 0.5 1.3e-11 44.2 0.5 2.5 3 1 1 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain PPL5 PF18168.1 EGF77534.1 - 0.55 9.5 6.2 0.43 9.8 4.7 1.6 1 1 1 2 2 2 0 Prim-pol family 5 zf-C2H2 PF00096.26 EGF77536.1 - 1.9e-10 40.6 20.0 0.00016 21.9 2.0 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF77536.1 - 2e-09 37.5 16.0 0.0034 18.1 1.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF77536.1 - 5.7e-06 26.5 13.4 0.016 15.5 1.8 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF77536.1 - 1.4e-05 25.3 4.5 0.38 11.2 0.1 4.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EGF77536.1 - 1.5e-05 25.2 0.4 1.5e-05 25.2 0.4 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 EGF77536.1 - 0.013 15.8 5.5 0.013 15.8 5.5 3.5 3 1 1 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EGF77536.1 - 0.021 14.6 1.8 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EGF77536.1 - 0.069 13.2 7.3 1.6 8.8 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger BBP1_N PF15271.6 EGF77536.1 - 0.077 13.8 0.6 1.9 9.3 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein zf-H2C2_5 PF13909.6 EGF77536.1 - 0.15 11.8 5.8 5.2 6.9 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf_ZIC PF18366.1 EGF77536.1 - 0.17 12.0 1.0 0.49 10.5 0.7 2.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-LYAR PF08790.11 EGF77536.1 - 0.79 9.7 5.0 20 5.2 0.2 3.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn_ribbon_SprT PF17283.2 EGF77536.1 - 1.7 8.6 5.7 1.1 9.3 1.5 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Peptidase_S9 PF00326.21 EGF77537.1 - 4.5e-56 189.7 0.1 1e-55 188.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 EGF77537.1 - 6.9e-07 29.0 0.4 0.0029 17.5 0.1 3.1 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 EGF77537.1 - 3.7e-05 22.6 0.0 0.0092 14.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EGF77537.1 - 0.00071 19.3 0.0 0.0057 16.3 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EGF77537.1 - 0.0022 17.9 0.0 0.095 12.5 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGF77537.1 - 0.0037 17.0 2.5 10 5.7 0.0 3.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Aa_trans PF01490.18 EGF77538.1 - 2.2e-25 89.2 25.8 6.2e-23 81.2 25.8 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein TIM21 PF08294.11 EGF77538.1 - 0.0035 17.2 0.2 0.023 14.6 0.1 2.2 2 0 0 2 2 2 1 TIM21 MWFE PF15879.5 EGF77538.1 - 0.24 11.6 1.3 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit RRM_1 PF00076.22 EGF77539.1 - 1.6e-29 101.5 1.1 4.1e-17 61.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF77539.1 - 0.0014 18.7 0.6 1.1 9.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif HlyIII PF03006.20 EGF77541.1 - 7.5e-24 84.7 14.3 3.7e-19 69.3 7.5 2.3 1 1 1 2 2 2 2 Haemolysin-III related Dynamitin PF04912.14 EGF77542.1 - 5.6e-52 177.4 14.3 1.5e-50 172.6 14.3 2.0 1 1 0 1 1 1 1 Dynamitin BMFP PF04380.13 EGF77542.1 - 0.0078 16.7 0.4 0.6 10.6 0.0 3.2 3 0 0 3 3 3 1 Membrane fusogenic activity DUF3294 PF07957.11 EGF77542.1 - 0.041 13.6 0.9 0.23 11.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) USP19_linker PF16602.5 EGF77542.1 - 0.042 14.4 0.5 2.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase Pox_F11 PF04943.12 EGF77542.1 - 0.088 11.9 2.0 0.082 12.0 0.2 1.7 2 0 0 2 2 2 0 Poxvirus F11 protein DUF4047 PF13256.6 EGF77542.1 - 0.16 12.2 1.1 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF2203 PF09969.9 EGF77542.1 - 0.83 10.4 5.0 1.1 9.9 0.2 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 EGF77542.1 - 6.1 7.0 8.9 0.72 10.0 0.3 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Cyclin_N PF00134.23 EGF77543.1 - 1.1e-08 34.9 0.4 2.4e-08 33.8 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGF77543.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat SPRY PF00622.28 EGF77544.1 - 2.7e-16 59.8 2.6 1.5e-10 41.2 0.3 2.9 3 0 0 3 3 3 2 SPRY domain F-box_4 PF15966.5 EGF77544.1 - 0.0013 18.6 0.3 0.0043 16.9 0.3 1.9 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGF77544.1 - 0.011 15.6 0.4 0.023 14.6 0.4 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGF77544.1 - 0.043 13.7 0.2 0.093 12.6 0.2 1.5 1 0 0 1 1 1 0 F-box domain Phi_1 PF04674.12 EGF77545.1 - 1.3e-34 119.8 1.6 3.6e-34 118.3 1.6 1.9 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region BLOC1_2 PF10046.9 EGF77545.1 - 0.1 12.9 26.3 0.19 12.0 4.8 4.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ALIX_LYPXL_bnd PF13949.6 EGF77546.1 - 0.0023 17.3 0.1 0.0051 16.1 0.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MRP-S26 PF14943.6 EGF77546.1 - 0.0054 16.7 4.9 0.15 12.0 0.2 2.5 2 0 0 2 2 2 2 Mitochondrial ribosome subunit S26 DUF4140 PF13600.6 EGF77546.1 - 0.028 14.8 0.3 0.06 13.8 0.3 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SET PF00856.28 EGF77548.1 - 5.9e-09 36.5 0.0 1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Urm1 PF09138.11 EGF77549.1 - 2.7e-34 117.4 0.0 3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGF77549.1 - 1.8e-05 25.3 0.0 2.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family RsdA_SigD_bd PF16751.5 EGF77550.1 - 0.1 12.9 0.4 0.27 11.5 0.4 1.7 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Cwf_Cwc_15 PF04889.12 EGF77550.1 - 0.28 10.9 8.9 0.47 10.1 8.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hamartin PF04388.12 EGF77550.1 - 6 5.4 11.9 6.4 5.3 11.9 1.0 1 0 0 1 1 1 0 Hamartin protein RRM_1 PF00076.22 EGF77551.1 - 3e-23 81.4 0.1 6.8e-12 45.0 0.0 2.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF77551.1 - 1.8e-11 43.7 0.0 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF77551.1 - 3.3e-07 30.1 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif NOA36 PF06524.12 EGF77551.1 - 0.17 11.2 3.7 0.25 10.6 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein HD PF01966.22 EGF77553.1 - 0.092 13.0 0.6 0.41 10.9 0.6 2.1 1 1 0 1 1 1 0 HD domain Enkurin PF13864.6 EGF77553.1 - 0.67 10.4 6.7 1.1 9.7 0.1 3.4 3 0 0 3 3 3 0 Calmodulin-binding DUF21 PF01595.20 EGF77554.1 - 3.9e-31 108.1 0.2 5.6e-31 107.6 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGF77554.1 - 2.3e-07 31.2 1.4 0.023 15.1 0.1 3.4 3 0 0 3 3 3 3 CBS domain SpoIISA_toxin PF14171.6 EGF77554.1 - 0.13 12.0 0.0 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Abhydrolase_6 PF12697.7 EGF77555.1 - 1.7e-14 55.0 0.0 2.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGF77555.1 - 1.1e-13 51.5 0.0 3.1e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF77555.1 - 1.5e-08 34.2 0.0 2.8e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EGF77555.1 - 7.2e-07 28.2 0.0 8.8e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EGF77555.1 - 0.0052 16.9 0.0 0.0055 16.8 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 EGF77555.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.13 EGF77555.1 - 0.04 13.8 0.0 0.081 12.8 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 EGF77555.1 - 0.06 13.0 0.0 0.097 12.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Amidohydro_2 PF04909.14 EGF77557.1 - 2.4e-62 211.3 0.0 2.7e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.21 EGF77557.1 - 0.034 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Ras PF00071.22 EGF77558.1 - 5.4e-66 221.2 0.1 7.4e-66 220.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF77558.1 - 6.2e-35 120.0 0.0 1.1e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF77558.1 - 2.2e-14 53.3 0.1 2.9e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF77558.1 - 9e-06 25.3 0.1 3.1e-05 23.6 0.1 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGF77558.1 - 9e-05 21.9 0.1 0.00014 21.3 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGF77558.1 - 0.00018 21.5 0.4 0.28 11.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGF77558.1 - 0.00028 21.0 0.1 0.00076 19.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGF77558.1 - 0.0058 15.8 2.3 0.13 11.4 0.4 2.7 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 EGF77558.1 - 0.037 13.5 0.0 0.048 13.1 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EGF77558.1 - 0.048 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3963 PF13124.6 EGF77558.1 - 0.063 13.3 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_16 PF13191.6 EGF77558.1 - 0.072 13.5 0.0 0.099 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGF77558.1 - 0.083 13.2 0.1 0.49 10.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain CLP_protease PF00574.23 EGF77559.1 - 2.9e-73 245.7 0.2 4.7e-73 244.9 0.2 1.3 1 1 0 1 1 1 1 Clp protease HHH PF00633.23 EGF77560.1 - 0.00041 20.1 0.1 0.0011 18.7 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGF77560.1 - 0.078 13.6 0.2 0.46 11.1 0.1 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 EGF77560.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family ING PF12998.7 EGF77561.1 - 2.9e-16 59.9 0.9 4.2e-16 59.4 0.9 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGF77561.1 - 5.2e-06 26.3 7.3 9.5e-06 25.4 7.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGF77561.1 - 0.012 15.9 0.9 0.025 14.8 0.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C4pol PF14260.6 EGF77561.1 - 4 8.0 6.3 0.35 11.4 1.0 2.0 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF3919 PF13057.6 EGF77562.1 - 0.18 11.3 3.3 0.24 11.0 2.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) CC2-LZ PF16516.5 EGF77562.1 - 0.34 11.3 9.0 0.16 12.4 1.0 2.9 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Bcr-Abl_Oligo PF09036.10 EGF77562.1 - 0.39 10.8 5.3 0.75 9.8 0.3 2.8 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Fez1 PF06818.15 EGF77562.1 - 0.4 11.1 14.3 0.51 10.8 8.9 2.2 1 1 1 2 2 2 0 Fez1 Cortex-I_coil PF09304.10 EGF77562.1 - 0.45 10.8 12.8 0.14 12.4 7.7 2.6 1 1 0 2 2 2 0 Cortexillin I, coiled coil DivIVA PF05103.13 EGF77562.1 - 1.8 8.7 10.1 0.47 10.5 1.7 3.0 1 1 1 2 2 2 0 DivIVA protein YlqD PF11068.8 EGF77562.1 - 3.7 7.9 10.6 1.2 9.6 4.2 2.3 1 1 1 2 2 2 0 YlqD protein Fzo_mitofusin PF04799.13 EGF77562.1 - 5.2 6.6 14.8 0.12 11.9 4.8 2.4 2 1 1 3 3 3 0 fzo-like conserved region TBPIP PF07106.13 EGF77563.1 - 4.5e-19 68.1 1.4 1e-18 67.0 1.4 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 EGF77563.1 - 0.00027 21.0 0.6 0.00066 19.7 0.2 1.9 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 EGF77563.1 - 0.027 14.8 2.0 0.11 12.9 0.0 2.6 2 1 0 3 3 3 0 Penicillinase repressor Ipi1_N PF12333.8 EGF77564.1 - 7.7e-12 45.7 0.4 4.3e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation M11L PF11099.8 EGF77564.1 - 0.014 15.7 0.3 0.051 13.9 0.3 2.0 1 0 0 1 1 1 0 Apoptosis regulator M11L like Utp13 PF08625.11 EGF77564.1 - 0.05 13.5 0.1 0.25 11.2 0.1 2.3 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain DUF4061 PF13270.6 EGF77565.1 - 0.00014 22.1 1.3 0.00031 21.0 1.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4061) GH97_C PF14509.6 EGF77565.1 - 0.14 12.4 0.3 0.2 11.9 0.3 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Cpn60_TCP1 PF00118.24 EGF77566.1 - 3.1e-161 537.3 5.6 3.5e-161 537.2 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ASH PF15780.5 EGF77567.1 - 3.5e-07 30.3 0.0 17 5.7 0.0 7.5 7 0 0 7 7 7 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGF77567.1 - 1.1e-06 28.4 3.7 12 5.7 0.1 7.9 8 1 0 8 8 8 3 MSP (Major sperm protein) domain PapD-like PF14874.6 EGF77567.1 - 4.4e-06 26.8 0.1 0.00014 22.0 0.0 3.3 4 0 0 4 4 4 1 Flagellar-associated PapD-like Methyltransf_25 PF13649.6 EGF77568.1 - 8.2e-12 45.7 0.4 2.9e-11 43.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF77568.1 - 2.3e-10 40.4 0.5 5.1e-10 39.3 0.4 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGF77568.1 - 6.6e-10 38.9 0.1 1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGF77568.1 - 2.5e-09 37.6 0.1 2.7e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF77568.1 - 1.2e-08 35.0 0.1 9.9e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGF77568.1 - 3.4e-06 26.2 0.2 5.2e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGF77568.1 - 4.9e-05 22.7 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGF77568.1 - 0.00022 20.8 0.2 0.00034 20.2 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGF77568.1 - 0.00023 21.9 0.0 0.00047 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGF77568.1 - 0.00034 20.6 0.5 0.00058 19.8 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGF77568.1 - 0.0039 17.3 0.4 0.0097 16.0 0.3 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase PRMT5 PF05185.16 EGF77568.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 EGF77568.1 - 0.0093 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EGF77568.1 - 0.019 14.7 0.2 0.03 14.1 0.2 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 EGF77568.1 - 0.021 14.4 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PRMT5_C PF17286.2 EGF77568.1 - 0.062 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_24 PF13578.6 EGF77568.1 - 0.1 13.6 0.0 0.2 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Bap31 PF05529.12 EGF77569.1 - 2.2e-42 144.1 8.2 3.1e-42 143.6 8.2 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGF77569.1 - 1.4e-05 25.0 8.4 2.5e-05 24.2 8.4 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain CbtA PF09490.10 EGF77569.1 - 0.02 14.7 0.5 0.02 14.7 0.5 1.7 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) SieB PF14163.6 EGF77569.1 - 1.5 8.3 5.2 2 7.9 0.3 2.2 1 1 1 2 2 2 0 Super-infection exclusion protein B Tom37 PF10568.9 EGF77570.1 - 1.6e-26 93.0 0.0 3.9e-26 91.8 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EGF77570.1 - 1.7e-19 70.4 0.0 3.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGF77570.1 - 1.2e-12 47.4 0.1 2.4e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGF77570.1 - 5.7e-06 26.3 0.0 2.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGF77570.1 - 1.1e-05 25.5 0.2 3.9e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGF77570.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain UNC45-central PF11701.8 EGF77571.1 - 7e-19 68.3 26.6 2.1e-18 66.7 5.2 5.2 7 0 0 7 7 7 2 Myosin-binding striated muscle assembly central Arm PF00514.23 EGF77571.1 - 4.8e-13 48.6 7.7 0.0015 18.5 0.0 8.6 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGF77571.1 - 9.3e-09 35.6 10.3 0.00045 20.6 0.3 6.6 5 3 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF77571.1 - 0.03 14.9 11.1 0.36 11.5 0.1 5.3 5 2 1 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGF77571.1 - 0.04 14.4 6.7 73 4.0 0.1 6.9 8 1 1 9 9 9 0 HEAT-like repeat DIM1 PF02966.16 EGF77571.1 - 0.073 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Mitosis protein DIM1 FCH PF00611.23 EGF77571.1 - 0.11 12.9 0.0 0.62 10.4 0.0 2.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain CEP19 PF14933.6 EGF77571.1 - 0.42 10.9 2.5 1 9.7 1.4 2.2 1 1 1 2 2 2 0 CEP19-like protein RTTN_N PF14726.6 EGF77571.1 - 0.6 10.9 3.0 3 8.7 0.1 3.4 3 1 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Sec7_N PF12783.7 EGF77571.1 - 7.3 6.5 9.9 0.49 10.3 1.5 3.2 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RasGAP PF00616.19 EGF77572.1 - 4.6e-47 160.4 3.4 4.6e-47 160.4 3.4 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGF77572.1 - 3.2e-43 147.2 6.5 3.2e-43 147.2 6.5 3.3 3 0 0 3 3 3 1 RasGAP C-terminus CH PF00307.31 EGF77572.1 - 1.4e-16 60.6 0.1 9.1e-16 58.0 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 EGF77572.1 - 1.1e-10 40.3 14.3 0.0001 21.8 0.3 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 EGF77572.1 - 0.014 15.2 0.1 0.52 10.2 0.0 2.8 2 0 0 2 2 2 0 CAMSAP CH domain RsbU_N PF08673.10 EGF77572.1 - 0.81 9.8 5.6 3.8 7.7 0.2 3.8 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain Sybindin PF04099.12 EGF77573.1 - 1.2e-43 148.5 0.1 1.3e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGF77573.1 - 2.8e-07 30.7 0.0 2.8e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region bZIP_1 PF00170.21 EGF77574.1 - 4e-11 42.9 6.7 6.6e-11 42.1 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGF77574.1 - 1.1e-09 38.2 8.6 1.7e-09 37.6 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGF77574.1 - 9.6e-06 26.0 1.4 1.4e-05 25.5 1.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ASD2 PF08687.11 EGF77574.1 - 0.00025 20.7 3.4 0.0003 20.5 3.4 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 DUF4201 PF13870.6 EGF77574.1 - 0.00071 19.4 3.5 0.00099 18.9 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF2514 PF10721.9 EGF77574.1 - 0.0036 17.4 0.5 0.0053 16.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) DivIC PF04977.15 EGF77574.1 - 0.011 15.5 0.4 0.018 14.8 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 EGF77574.1 - 0.032 14.4 0.2 0.053 13.8 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper COX4_pro_2 PF07835.12 EGF77575.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV GCN5L1 PF06320.13 EGF77576.1 - 5.9e-26 90.9 0.9 5.9e-26 90.9 0.9 1.5 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Mod_r PF07200.13 EGF77576.1 - 0.012 15.7 0.3 0.012 15.7 0.3 1.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4606 PF15379.6 EGF77576.1 - 0.053 13.8 0.3 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Sec2p PF06428.11 EGF77576.1 - 0.83 9.7 6.9 0.059 13.4 1.6 1.9 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p WXG100 PF06013.12 EGF77576.1 - 1.1 9.5 6.1 0.67 10.2 0.3 2.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Mob1_phocein PF03637.17 EGF77577.1 - 2.4e-33 115.5 0.2 3.1e-33 115.2 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Ank_4 PF13637.6 EGF77578.1 - 2.7e-19 69.3 1.6 4.7e-11 43.0 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF77578.1 - 2.7e-11 43.9 0.1 4.6e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGF77578.1 - 1.1e-09 37.7 1.2 7.8e-07 28.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGF77578.1 - 4.9e-09 36.3 0.7 1.1e-08 35.1 0.4 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF77578.1 - 5.6e-08 32.9 0.1 2.3e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat HEAT PF02985.22 EGF77579.1 - 1.7e-40 133.5 32.3 0.002 18.2 0.1 13.3 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 EGF77579.1 - 4.9e-34 116.6 15.4 2.8e-08 34.0 0.0 8.5 1 1 10 11 11 11 9 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF77579.1 - 2.7e-13 50.3 3.1 0.0031 18.1 0.1 6.9 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGF77579.1 - 2.8e-12 46.8 14.1 0.12 13.0 0.1 9.1 9 2 1 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 EGF77579.1 - 5e-10 39.6 11.6 0.00028 21.0 0.1 5.1 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGF77579.1 - 9.5e-09 34.3 12.0 2.9e-08 32.7 2.8 3.3 1 1 1 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 EGF77579.1 - 4.3e-07 30.1 4.5 0.72 10.0 0.3 4.5 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGF77579.1 - 5.4e-07 29.4 5.5 0.014 15.0 0.2 4.1 2 1 2 4 4 4 2 CLASP N terminal DNA_alkylation PF08713.11 EGF77579.1 - 0.00026 20.8 0.0 0.14 11.9 0.0 3.9 1 1 1 4 4 4 1 DNA alkylation repair enzyme IFRD PF05004.13 EGF77579.1 - 0.0003 20.0 5.7 0.029 13.5 1.1 4.3 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 EGF77579.1 - 0.008 16.2 3.1 47 4.2 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DRIM PF07539.12 EGF77579.1 - 0.31 9.3 10.0 1.4 7.1 1.0 3.5 2 1 1 4 4 4 0 Down-regulated in metastasis Proteasom_PSMB PF10508.9 EGF77579.1 - 0.38 9.2 5.6 6 5.3 0.1 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Polysacc_syn_2C PF08485.10 EGF77580.1 - 0.00073 19.2 16.1 0.37 10.5 1.0 5.0 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein C-terminal EMP24_GP25L PF01105.24 EGF77581.1 - 6.5e-42 143.5 1.4 7.4e-42 143.3 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COMP PF11598.8 EGF77581.1 - 0.14 12.7 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein eIF-6 PF01912.18 EGF77582.1 - 2e-81 272.1 0.1 2.8e-81 271.6 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family Sad1_UNC PF07738.13 EGF77583.1 - 8.6e-30 103.4 0.0 1.9e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ribosomal_S17 PF00366.20 EGF77584.1 - 8.9e-24 83.4 1.2 1.1e-23 83.1 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 SH3_15 PF18346.1 EGF77584.1 - 0.1 12.9 0.5 1.5 9.2 0.0 2.3 2 1 0 2 2 2 0 Mind bomb SH3 repeat domain SWIRM-assoc_2 PF16496.5 EGF77585.1 - 2.5e-32 112.3 1.4 3.8e-32 111.7 1.4 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 EGF77585.1 - 1.8e-10 41.0 0.4 4.2e-10 39.8 0.4 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EGF77585.1 - 2.1e-10 40.6 0.0 5.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF77585.1 - 1.3e-05 25.3 0.0 4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 EGF77585.1 - 0.00023 21.1 1.0 0.0005 20.0 1.0 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 SANT_DAMP1_like PF16282.5 EGF77585.1 - 0.013 15.7 0.0 0.045 13.9 0.0 2.0 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 ZZ PF00569.17 EGF77585.1 - 0.02 14.7 3.2 0.046 13.5 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type BRCT_2 PF16589.5 EGF77585.1 - 0.021 15.2 0.1 0.11 12.9 0.1 2.1 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGF77585.1 - 0.039 14.2 0.2 9.4 6.6 0.0 2.4 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain NPP1 PF05630.11 EGF77585.1 - 0.051 13.7 0.3 0.12 12.5 0.3 1.7 1 1 0 1 1 1 0 Necrosis inducing protein (NPP1) SBD_N PF07005.11 EGF77585.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-binding N-terminal domain C1_2 PF03107.16 EGF77585.1 - 2.7 8.4 10.5 0.057 13.7 2.3 2.5 3 0 0 3 3 2 0 C1 domain RNase_PH PF01138.21 EGF77586.1 - 5.4e-23 81.9 0.1 1.2e-22 80.8 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGF77586.1 - 1.6e-14 53.7 0.0 3.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Prenyltrans PF00432.21 EGF77587.1 - 6.1e-20 70.7 5.6 3.7e-06 26.6 0.0 5.5 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat DUF5606 PF18347.1 EGF77587.1 - 0.091 13.0 0.4 0.16 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5606) DUF4246 PF14033.6 EGF77589.1 - 1.6e-61 208.8 0.2 1.8e-61 208.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Opacity PF02462.15 EGF77589.1 - 0.09 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Opacity family porin protein DUF3347 PF11827.8 EGF77590.1 - 0.073 13.3 4.3 0.1 12.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Tropomyosin_1 PF12718.7 EGF77591.1 - 0.0016 18.6 2.9 0.0022 18.1 2.9 1.1 1 0 0 1 1 1 1 Tropomyosin like SlyX PF04102.12 EGF77591.1 - 0.018 15.7 0.4 0.77 10.4 0.1 2.2 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 EGF77591.1 - 0.079 10.9 0.8 0.1 10.5 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.6 EGF77591.1 - 0.094 12.5 0.9 0.13 12.0 0.9 1.1 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 EGF77591.1 - 0.14 12.0 3.0 2.2 8.1 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator Phyto_Pns9_10 PF05878.11 EGF77591.1 - 0.14 11.2 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Prefoldin_2 PF01920.20 EGF77591.1 - 0.34 10.9 6.9 0.19 11.7 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit TMPIT PF07851.13 EGF77591.1 - 0.38 9.9 1.4 0.55 9.4 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sigma70_ner PF04546.13 EGF77593.1 - 0.024 14.5 6.9 0.032 14.1 6.9 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region GTP-bdg_M PF16360.5 EGF77593.1 - 1.1 10.0 7.6 7.3 7.3 0.6 2.3 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DDE_Tnp_4 PF13359.6 EGF77593.1 - 3.2 7.4 6.3 2.7 7.6 0.4 2.2 1 1 1 2 2 2 0 DDE superfamily endonuclease DUF4558 PF15104.6 EGF77593.1 - 4.8 7.3 11.5 0.24 11.5 4.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4558) Adaptin_N PF01602.20 EGF77595.1 - 5.7e-122 407.9 2.9 7.9e-122 407.5 2.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGF77595.1 - 3.1e-34 117.6 0.0 7.9e-34 116.2 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGF77595.1 - 9.3e-14 51.7 0.9 5.1e-13 49.3 0.4 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.6 EGF77595.1 - 0.013 15.8 1.0 1.8 9.0 0.1 4.2 4 1 1 5 5 5 0 HEAT repeats Coatomer_g_Cpla PF16381.5 EGF77595.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EGF77595.1 - 0.097 13.0 1.0 13 6.4 0.1 4.1 4 0 0 4 4 4 0 HEAT repeat 60KD_IMP PF02096.20 EGF77596.1 - 3.6e-18 66.0 9.0 4.5e-16 59.2 9.0 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein TetR_C_13 PF16925.5 EGF77596.1 - 0.055 13.4 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4781 PF16013.5 EGF77596.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF4598 PF15370.6 EGF77597.1 - 1.1e-14 54.8 0.3 1.1e-14 54.8 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Coatomer_E PF04733.14 EGF77598.1 - 1.6e-81 273.9 1.1 1.8e-81 273.7 1.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGF77598.1 - 7.1e-10 39.3 8.1 4.4e-05 23.9 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF77598.1 - 2.1e-08 34.3 0.3 0.0011 19.1 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGF77598.1 - 6.3e-06 25.9 1.4 0.3 11.3 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF77598.1 - 0.00019 21.6 0.1 0.54 10.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF77598.1 - 0.00021 21.9 4.6 1.2 10.1 0.0 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF77598.1 - 0.0011 19.2 0.0 3.7 8.1 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGF77598.1 - 0.0076 16.8 0.5 10 7.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF77598.1 - 0.0083 16.3 0.1 47 4.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGF77598.1 - 0.0099 15.5 0.1 5 6.9 0.2 2.7 2 0 0 2 2 2 1 TPR repeat PPR PF01535.20 EGF77598.1 - 0.011 15.9 0.5 17 5.9 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TPR_1 PF00515.28 EGF77598.1 - 0.013 15.3 1.1 0.75 9.7 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 EGF77598.1 - 0.022 14.7 0.4 0.049 13.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_16 PF13432.6 EGF77598.1 - 0.062 14.0 1.5 7.7 7.3 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGF77598.1 - 0.082 12.9 0.8 4.1 7.5 0.2 2.8 1 1 0 2 2 2 0 Putative TPR-like repeat YfdX PF10938.8 EGF77598.1 - 0.11 12.4 2.4 8.2 6.3 0.2 2.7 3 0 0 3 3 3 0 YfdX protein Avl9 PF09794.9 EGF77599.1 - 1.4e-93 313.6 0.1 2e-93 313.1 0.1 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EGF77599.1 - 0.00057 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 EGF77599.1 - 0.002 17.8 0.0 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Pro_isomerase PF00160.21 EGF77600.1 - 5e-42 143.9 0.0 5.6e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AMP-binding PF00501.28 EGF77601.1 - 6.6e-39 133.7 0.0 2.6e-38 131.7 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGF77601.1 - 8.5e-11 41.6 1.1 1.9e-10 40.5 1.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGF77601.1 - 0.036 15.1 0.0 0.11 13.5 0.0 1.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain CCDC53 PF10152.9 EGF77602.1 - 0.00015 22.2 0.0 0.00016 22.1 0.0 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex DUF1664 PF07889.12 EGF77602.1 - 0.037 14.1 0.0 0.039 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGF77602.1 - 0.046 14.0 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EGF77602.1 - 0.057 13.5 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EGF77602.1 - 0.13 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec15 PF04091.12 EGF77602.1 - 0.13 11.6 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF726 PF05277.12 EGF77603.1 - 0.013 14.4 0.0 0.017 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PWWP PF00855.17 EGF77604.1 - 1.6e-05 25.2 0.0 5.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 PWWP domain Amnionless PF14828.6 EGF77605.1 - 0.029 13.2 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Mito_carr PF00153.27 EGF77606.1 - 1.4e-60 201.3 5.2 1.6e-21 76.1 0.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF77606.1 - 0.017 14.3 0.0 4.1 6.5 0.0 2.6 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Myb_Cef PF11831.8 EGF77607.1 - 1.7e-40 139.1 0.8 1.7e-40 139.1 0.8 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGF77607.1 - 4.2e-23 81.3 4.0 5.3e-12 45.7 0.7 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF77607.1 - 7.8e-21 74.1 5.6 2e-13 50.4 2.8 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EGF77607.1 - 0.037 14.1 0.0 1.3 9.2 0.2 3.0 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LRR_4 PF12799.7 EGF77608.1 - 3.9e-15 55.7 13.6 0.00011 22.5 3.8 4.5 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF77608.1 - 3.4e-12 46.0 15.1 1.6e-05 24.6 8.5 4.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EGF77608.1 - 0.00023 20.7 2.9 0.0045 16.5 1.0 3.1 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 EGF77608.1 - 0.0074 16.3 13.6 1.7 8.9 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_2 PF07723.13 EGF77608.1 - 0.0086 16.7 0.2 4.9 8.0 0.0 3.2 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_1 PF00560.33 EGF77608.1 - 0.025 15.1 15.8 4.7 8.1 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich Repeat YukD PF08817.10 EGF77608.1 - 0.13 13.0 0.0 0.39 11.4 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD zf-C2H2 PF00096.26 EGF77609.1 - 5.9e-41 136.7 60.2 1.1e-05 25.6 1.4 10.2 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF77609.1 - 5.2e-22 76.6 55.6 0.0052 17.5 0.1 10.2 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF77609.1 - 3e-18 65.3 52.4 8e-07 29.2 1.2 9.5 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGF77609.1 - 4e-10 39.7 27.6 0.00099 19.3 0.0 7.7 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGF77609.1 - 2.5e-07 30.5 44.0 0.07 13.1 0.1 9.1 10 0 0 10 10 10 6 C2H2-type zinc finger zf-met PF12874.7 EGF77609.1 - 5.3e-07 29.8 24.4 0.047 14.1 0.1 8.0 8 0 0 8 8 7 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 EGF77609.1 - 7e-06 25.5 12.5 0.21 11.2 0.1 5.8 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 EGF77609.1 - 2e-05 24.8 35.2 0.15 12.4 8.6 5.2 1 1 4 5 5 5 4 C2H2-type zinc ribbon Rep_fac-A_C PF08646.10 EGF77609.1 - 0.00014 21.6 12.9 0.038 13.7 0.6 3.6 2 1 1 3 3 3 2 Replication factor-A C terminal domain zf_C2H2_ZHX PF18387.1 EGF77609.1 - 0.00049 19.7 16.0 0.067 12.8 1.2 5.4 2 1 2 4 4 4 3 Zinc-fingers and homeoboxes C2H2 finger domain TRAF6_Z2 PF18048.1 EGF77609.1 - 0.01 15.9 18.3 1.4 9.1 0.8 6.2 6 0 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_aberr PF17017.5 EGF77609.1 - 0.014 15.6 28.3 0.48 10.5 3.4 6.3 3 1 5 8 8 8 0 Aberrant zinc-finger zinc_ribbon_15 PF17032.5 EGF77609.1 - 1.4 9.7 20.0 9.5 7.1 0.4 4.3 3 1 1 4 4 4 0 zinc-ribbon family zf-C2H2_9 PF16293.5 EGF77609.1 - 7.8 6.4 25.9 0.56 10.1 0.4 7.2 7 1 2 9 9 9 0 C2H2 type zinc-finger (1 copy) SAE2 PF08573.10 EGF77610.1 - 1.5e-09 38.9 23.7 6.8e-06 27.2 3.3 3.9 3 2 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus WD40 PF00400.32 EGF77613.1 - 3e-16 59.5 10.8 4.7e-05 24.1 0.0 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77613.1 - 5.5e-07 29.8 0.0 0.079 13.3 0.0 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF77613.1 - 2.9e-05 23.5 0.0 0.00047 19.6 0.0 2.6 1 1 1 2 2 2 1 WD40-like domain N6-adenineMlase PF10237.9 EGF77614.1 - 5.5e-49 166.0 0.2 6.9e-49 165.7 0.2 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase CABS1 PF15367.6 EGF77614.1 - 0.0076 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Calcium-binding and spermatid-specific protein 1 Cons_hypoth95 PF03602.15 EGF77614.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ldh_1_C PF02866.18 EGF77615.1 - 3e-48 163.9 0.1 4.4e-48 163.4 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGF77615.1 - 6.1e-45 152.8 0.1 9e-45 152.2 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGF77615.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGF77615.1 - 0.11 12.9 0.4 0.33 11.4 0.0 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ubiquitin_2 PF14560.6 EGF77616.1 - 6.2e-25 87.5 0.1 2.4e-24 85.6 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin-like domain CAP_GLY PF01302.25 EGF77616.1 - 4.5e-23 81.0 2.1 8.4e-23 80.2 1.4 1.8 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 EGF77616.1 - 0.16 11.7 0.0 0.48 10.2 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin family PhoLip_ATPase_C PF16212.5 EGF77617.1 - 1.4e-64 218.3 24.1 1.4e-64 218.3 24.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGF77617.1 - 5.7e-15 54.8 2.2 1.5e-14 53.4 2.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGF77617.1 - 9e-12 45.7 0.2 9.1e-08 32.6 0.2 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGF77617.1 - 6.4e-11 42.2 0.0 1.2e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGF77617.1 - 2e-10 40.5 0.0 9.2e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGF77617.1 - 5.6e-05 23.0 0.3 0.00059 19.6 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PH PF00169.29 EGF77620.1 - 2.6e-07 31.1 1.4 6e-07 29.9 0.0 2.4 3 0 0 3 3 3 1 PH domain Kinesin PF00225.23 EGF77621.1 - 3.2e-120 401.0 0.1 3.2e-120 401.0 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGF77621.1 - 7.1e-24 84.4 0.0 7.1e-24 84.4 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding AAA_30 PF13604.6 EGF77621.1 - 0.0058 16.4 0.1 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGF77621.1 - 0.31 11.3 0.0 0.31 11.3 0.0 3.4 2 1 1 3 3 3 0 AAA domain Use1 PF09753.9 EGF77621.1 - 0.34 10.6 32.7 0.3 10.8 14.9 2.7 2 1 1 3 3 3 0 Membrane fusion protein Use1 Kinesin_assoc PF16183.5 EGF77621.1 - 1.2 9.2 23.1 0.32 11.1 16.7 2.9 3 1 0 3 3 3 0 Kinesin-associated IZUMO PF15005.6 EGF77621.1 - 1.4 9.4 16.4 0.26 11.8 12.4 1.8 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Ribosomal_L22 PF00237.19 EGF77622.1 - 5.3e-40 135.8 0.3 7.4e-40 135.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Lactamase_B_2 PF12706.7 EGF77623.1 - 1.6e-41 142.0 0.1 1.9e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF77623.1 - 8.9e-13 48.5 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGF77623.1 - 0.012 15.6 0.6 0.04 13.9 0.4 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Fcf2 PF08698.11 EGF77624.1 - 8.9e-39 131.8 0.3 8.9e-39 131.8 0.3 1.5 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing ORMDL PF04061.14 EGF77625.1 - 1.1e-54 183.9 5.7 1.2e-54 183.7 5.7 1.0 1 0 0 1 1 1 1 ORMDL family Myosin_head PF00063.21 EGF77626.1 - 1.3e-261 869.6 4.9 2.7e-261 868.6 4.9 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EGF77626.1 - 7.3e-29 100.1 3.1 1e-28 99.7 1.1 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 EGF77626.1 - 6e-16 56.7 46.2 1.9e-05 24.0 3.1 6.8 6 0 0 6 6 6 6 IQ calmodulin-binding motif DHR10 PF18595.1 EGF77626.1 - 0.0052 16.8 4.5 0.0052 16.8 4.5 2.8 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain DUF16 PF01519.16 EGF77626.1 - 0.019 15.5 13.0 0.04 14.4 2.8 3.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 HTH_Tnp_1 PF01527.20 EGF77626.1 - 0.028 14.7 3.6 3.7 7.9 0.3 3.5 3 0 0 3 3 3 0 Transposase AAA_22 PF13401.6 EGF77626.1 - 0.068 13.4 1.7 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 EGF77626.1 - 0.17 12.1 21.9 0.036 14.3 6.2 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding EDR1 PF14381.6 EGF77626.1 - 0.25 11.1 2.9 3.4 7.3 2.3 2.9 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 ATG16 PF08614.11 EGF77626.1 - 0.36 11.0 23.5 0.32 11.2 3.7 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fungal_trans_2 PF11951.8 EGF77626.1 - 0.45 9.3 5.9 1.3 7.7 3.3 2.5 2 1 1 3 3 3 0 Fungal specific transcription factor domain ZapB PF06005.12 EGF77626.1 - 0.62 10.5 21.4 3.1 8.3 8.8 3.8 3 0 0 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 EGF77626.1 - 0.89 9.6 11.2 5 7.2 5.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 EGF77626.1 - 2.2 8.4 6.4 23 5.1 0.2 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation YabA PF06156.13 EGF77626.1 - 2.4 8.8 14.5 0.38 11.4 2.4 3.4 2 1 1 3 3 2 0 Initiation control protein YabA Noelin-1 PF12308.8 EGF77626.1 - 4 7.5 6.9 6.6 6.8 0.4 3.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein Ribosomal_S14 PF00253.21 EGF77628.1 - 6.8e-22 77.0 0.8 2.2e-21 75.4 0.1 2.0 2 1 1 3 3 3 1 Ribosomal protein S14p/S29e DUF3194 PF11419.8 EGF77628.1 - 0.19 12.1 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Polysacc_deac_1 PF01522.21 EGF77629.1 - 3.3e-29 101.3 0.0 8e-29 100.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 EGF77630.1 - 6e-37 126.3 0.0 1.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Fasciclin PF02469.22 EGF77631.1 - 9e-44 148.8 0.1 8.3e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Abhydrolase_1 PF00561.20 EGF77632.1 - 4.2e-20 72.5 0.5 7.1e-15 55.3 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF77632.1 - 1.8e-18 68.0 0.0 2.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGF77632.1 - 9.3e-10 38.6 0.3 6.6e-06 26.0 0.3 2.3 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 EGF77632.1 - 4.8e-09 36.7 0.0 5.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EGF77632.1 - 2e-08 33.8 0.3 5.2e-08 32.4 0.3 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EGF77632.1 - 0.0092 14.9 0.1 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.20 EGF77632.1 - 0.012 15.3 0.1 0.063 12.9 0.2 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_3 PF07859.13 EGF77632.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EGF77632.1 - 0.017 14.1 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGF77632.1 - 0.05 12.6 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Palm_thioest PF02089.15 EGF77632.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Peptidase_C48 PF02902.19 EGF77633.1 - 6.1e-33 114.5 0.1 3.2e-17 63.1 0.1 2.8 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SHIPPO-rpt PF07004.12 EGF77634.1 - 2.7e-08 34.3 23.3 0.095 13.7 0.1 6.7 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat STE PF02200.16 EGF77635.1 - 4.6e-52 175.1 0.1 5.2e-52 174.9 0.1 1.0 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EGF77636.1 - 0.00049 20.4 4.8 0.0011 19.3 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGF77636.1 - 0.021 15.5 0.1 0.046 14.4 0.1 1.6 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EGF77636.1 - 0.058 14.3 3.9 0.14 13.1 3.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGF77636.1 - 0.1 13.2 0.9 0.29 11.8 0.9 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain AMP-binding PF00501.28 EGF77637.1 - 2.8e-91 306.2 0.0 3.6e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF77637.1 - 3.1e-17 63.3 0.2 6.3e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Bromodomain PF00439.25 EGF77638.1 - 1.2e-16 60.5 0.8 3e-16 59.3 0.8 1.6 1 0 0 1 1 1 1 Bromodomain Ank_2 PF12796.7 EGF77638.1 - 3.1e-08 34.1 0.0 5.7e-07 30.0 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF77638.1 - 4.3e-07 30.1 0.1 0.002 18.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF77638.1 - 4.5e-05 23.5 0.0 1.5 9.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGF77638.1 - 0.0012 19.3 0.0 0.021 15.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF77638.1 - 0.0028 18.1 1.3 2 9.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat DUF3614 PF12267.8 EGF77638.1 - 2.2 8.8 8.5 1.7 9.1 3.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) Pkinase PF00069.25 EGF77639.1 - 2.5e-41 141.8 0.0 8.7e-41 140.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77639.1 - 5e-19 68.6 0.0 1.5e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF77639.1 - 0.00086 19.3 0.0 0.0061 16.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF77639.1 - 0.016 14.5 0.0 0.067 12.5 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGF77639.1 - 0.086 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF77639.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_1b PF00579.25 EGF77640.1 - 4.6e-18 65.5 0.0 6.3e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Carboxyl_trans PF01039.22 EGF77641.1 - 3.2e-186 619.8 0.0 3.7e-186 619.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGF77641.1 - 0.0047 16.4 0.1 0.028 13.9 0.0 2.3 3 0 0 3 3 3 1 Malonate decarboxylase gamma subunit (MdcE) Peptidase_S9 PF00326.21 EGF77642.1 - 3.7e-35 121.3 0.0 5.3e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGF77642.1 - 9.2e-06 25.5 0.5 0.14 11.8 0.9 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF77642.1 - 2.6e-05 23.6 0.0 0.023 14.0 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EGF77642.1 - 0.0011 18.5 0.0 0.0043 16.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGF77642.1 - 0.0079 16.1 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.12 EGF77642.1 - 0.038 13.9 0.2 1.8 8.6 0.2 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat THOC7 PF05615.13 EGF77643.1 - 1.2e-24 87.1 6.5 1.2e-24 87.1 6.5 1.6 2 0 0 2 2 2 1 Tho complex subunit 7 D5_N PF08706.11 EGF77643.1 - 0.11 12.8 0.5 0.15 12.3 0.5 1.4 1 0 0 1 1 1 0 D5 N terminal like LUC7 PF03194.15 EGF77643.1 - 0.11 12.1 6.5 0.16 11.6 6.5 1.2 1 0 0 1 1 1 0 LUC7 N_terminus LRR_9 PF14580.6 EGF77644.1 - 2.7e-09 36.8 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGF77644.1 - 2.1e-07 31.2 0.3 6.9e-07 29.5 0.2 2.0 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF77644.1 - 2.1e-05 24.2 2.2 0.0044 16.8 0.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat Calcipressin PF04847.12 EGF77646.1 - 6.6e-24 84.7 0.0 8.4e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Acyltransferase PF01553.21 EGF77647.1 - 2.3e-08 33.7 0.0 1.2e-07 31.5 0.0 2.1 1 1 1 2 2 2 1 Acyltransferase Ribosomal_L38e PF01781.18 EGF77648.1 - 1.9e-34 117.6 5.2 2e-34 117.5 5.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Gar1 PF04410.14 EGF77649.1 - 1.3e-43 148.4 0.7 2.8e-43 147.3 0.0 1.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region MFMR_assoc PF16596.5 EGF77649.1 - 0.02 15.4 1.2 0.02 15.4 1.2 3.1 3 0 0 3 3 3 0 Disordered region downstream of MFMR IMD PF08397.11 EGF77649.1 - 0.18 11.1 3.1 0.29 10.5 3.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain PI3_PI4_kinase PF00454.27 EGF77650.1 - 1.7e-45 155.8 0.0 3.7e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 EGF77650.1 - 1.1e-38 133.3 1.0 4e-30 105.0 0.0 2.5 2 0 0 2 2 2 2 NUC194 domain FATC PF02260.20 EGF77650.1 - 1.4e-10 40.8 0.0 3.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EGF77650.1 - 3.9e-09 36.2 2.4 3e-08 33.3 0.2 2.8 3 0 0 3 3 3 1 FAT domain Formyl_trans_N PF00551.19 EGF77651.1 - 2.6e-50 170.7 0.2 3e-50 170.5 0.2 1.0 1 0 0 1 1 1 1 Formyl transferase HMA PF00403.26 EGF77652.1 - 2.4e-09 37.5 0.3 3.6e-09 36.9 0.3 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Spore_YhcN_YlaJ PF09580.10 EGF77652.1 - 0.043 13.9 0.2 0.069 13.2 0.2 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TFIIS_M PF07500.14 EGF77653.1 - 1.5e-25 89.9 0.4 1.5e-25 89.9 0.4 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGF77653.1 - 2.6e-18 65.6 9.8 2.6e-18 65.6 9.8 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGF77653.1 - 1.7e-12 47.1 0.8 5.5e-12 45.5 0.8 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ppx-GppA PF02541.16 EGF77653.1 - 0.0016 18.0 0.2 0.0016 18.0 0.2 2.0 2 0 0 2 2 2 1 Ppx/GppA phosphatase family DUF4124 PF13511.6 EGF77653.1 - 0.0033 17.7 0.1 0.0085 16.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) EVC2_like PF12297.8 EGF77653.1 - 0.0054 15.5 0.1 0.011 14.4 0.1 1.5 1 1 0 1 1 1 1 Ellis van Creveld protein 2 like protein DcpS PF05652.12 EGF77653.1 - 0.3 12.0 2.2 9.4 7.1 0.3 2.4 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal Peptidase_M24 PF00557.24 EGF77654.1 - 3.6e-49 167.3 0.0 4.5e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGF77654.1 - 1.2e-15 57.5 8.7 1.2e-15 57.5 8.7 1.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EGF77654.1 - 2.8e-05 23.9 5.6 2.8e-05 23.9 5.6 2.0 2 0 0 2 2 2 1 HIT zinc finger zf-MYND PF01753.18 EGF77654.1 - 3.9e-05 23.6 4.9 0.00013 21.9 4.9 2.0 1 0 0 1 1 1 1 MYND finger DZR PF12773.7 EGF77654.1 - 1.4 9.0 6.7 3.3 7.8 6.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF4187 PF13821.6 EGF77655.1 - 1e-17 63.6 1.7 2.3e-17 62.5 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EGF77655.1 - 3.5e-14 52.4 0.6 6.6e-14 51.5 0.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF77655.1 - 2.9e-06 27.3 0.1 6.5e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 G-patch domain CppA_C PF14507.6 EGF77655.1 - 0.086 13.6 0.1 0.19 12.5 0.1 1.5 1 0 0 1 1 1 0 CppA C-terminal zf-C2H2_4 PF13894.6 EGF77656.1 - 0.0028 18.4 1.0 2.6 9.1 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF77656.1 - 0.0037 17.6 5.2 0.92 10.1 0.1 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGF77656.1 - 0.0065 16.7 3.5 0.019 15.3 0.4 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGF77656.1 - 0.024 14.6 0.3 6.4 6.9 0.0 2.5 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 EGF77656.1 - 1.1 9.6 3.6 1.3 9.4 1.5 2.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pantoate_ligase PF02569.15 EGF77658.1 - 3.8e-102 341.1 0.1 4.3e-102 340.9 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase RRM_1 PF00076.22 EGF77659.1 - 0.00028 20.6 0.0 0.019 14.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4633 PF15464.6 EGF77659.1 - 0.9 9.7 5.6 9.5 6.4 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4633) Ribonuc_2-5A PF06479.12 EGF77660.1 - 4.8e-34 117.3 0.0 7.7e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EGF77660.1 - 1.3e-30 106.7 0.0 1.8e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77660.1 - 2.5e-19 69.6 0.0 3.5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77660.1 - 8e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF77660.1 - 0.0029 17.0 0.1 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGF77660.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 EGF77660.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_22 PF13401.6 EGF77661.1 - 0.0018 18.5 0.0 0.016 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain HNH_2 PF13391.6 EGF77662.1 - 2.8e-06 27.4 0.1 9.9e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease Baculo_DNA_bind PF04786.12 EGF77662.1 - 0.097 12.0 0.3 0.17 11.2 0.3 1.3 1 0 0 1 1 1 0 ssDNA binding protein HNH PF01844.23 EGF77662.1 - 0.19 12.0 2.2 1.8 8.8 2.2 2.5 1 1 0 1 1 1 0 HNH endonuclease Cytochrome_C7 PF14522.6 EGF77662.1 - 0.2 11.6 1.7 5.2 7.1 0.1 2.5 1 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF77662.1 - 1.1 9.0 4.9 5 7.0 0.2 2.7 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF2039 PF10217.9 EGF77663.1 - 4.7e-28 97.3 12.6 7.6e-28 96.7 12.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) PIN_2 PF10130.9 EGF77663.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 PIN domain PolC_DP2 PF03833.13 EGF77663.1 - 0.53 8.1 6.1 0.56 8.0 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Importin_rep_4 PF18808.1 EGF77663.1 - 1.8 8.9 5.2 3.3 8.0 5.2 1.4 1 0 0 1 1 1 0 Importin repeat Cript PF10235.9 EGF77663.1 - 6.3 7.5 16.7 17 6.1 16.3 2.1 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Ras PF00071.22 EGF77664.1 - 6.9e-38 129.8 0.4 1.8e-28 99.2 0.2 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGF77664.1 - 1.1e-24 86.9 0.1 2.3e-23 82.7 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF77664.1 - 1.9e-08 34.0 0.1 1.2e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family ATPase_2 PF01637.18 EGF77664.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EGF77664.1 - 0.00024 21.1 0.1 0.33 10.8 0.0 2.7 2 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 EGF77664.1 - 0.00028 20.3 0.1 0.00037 19.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGF77664.1 - 0.0032 17.9 0.0 0.0033 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EGF77664.1 - 0.0044 16.8 0.2 0.091 12.5 0.0 2.2 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGF77664.1 - 0.0047 16.5 0.2 0.0096 15.4 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region SRPRB PF09439.10 EGF77664.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGF77664.1 - 0.013 15.8 0.1 0.031 14.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGF77664.1 - 0.015 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGF77664.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGF77664.1 - 0.028 14.8 0.3 0.079 13.4 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EGF77664.1 - 0.049 13.7 0.0 0.089 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGF77664.1 - 0.055 13.6 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGF77664.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 EGF77664.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 EGF77664.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Cyclin_N PF00134.23 EGF77665.1 - 1.3e-17 63.7 0.1 3.9e-15 55.7 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF77665.1 - 1.9e-06 27.9 1.4 9.5e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 Cyclin, C-terminal domain TFIIB PF00382.19 EGF77665.1 - 0.075 13.1 0.2 0.81 9.8 0.1 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat RB_B PF01857.20 EGF77665.1 - 0.17 11.9 0.3 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Retinoblastoma-associated protein B domain Asp PF00026.23 EGF77666.1 - 4.1e-13 49.5 0.0 1.1e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77666.1 - 0.035 13.9 0.1 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Retrotran_gag_2 PF14223.6 EGF77668.1 - 5.6e-09 35.8 1.1 9.3e-09 35.1 1.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Asp PF00026.23 EGF77671.1 - 1.1e-12 48.1 0.1 2e-12 47.2 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77671.1 - 1.6e-05 24.7 0.4 9.8e-05 22.2 0.1 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Diacid_rec PF05651.13 EGF77671.1 - 0.053 13.2 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Putative sugar diacid recognition DUF1539 PF07560.11 EGF77673.1 - 0.011 15.8 3.4 3.7 7.6 1.6 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) Phage_TAC_12 PF12363.8 EGF77673.1 - 0.046 14.1 0.2 14 6.1 0.1 2.9 2 1 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Spt4 PF06093.13 EGF77673.1 - 0.14 12.3 0.2 21 5.3 0.0 3.2 4 0 0 4 4 4 0 Spt4/RpoE2 zinc finger DNA_mis_repair PF01119.19 EGF77673.1 - 0.2 11.3 1.2 1 9.1 1.2 2.1 1 1 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain DUF4692 PF15763.5 EGF77674.1 - 3.3 8.2 7.3 0.24 11.9 1.4 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Tom22 PF04281.13 EGF77674.1 - 8.4 6.2 9.5 0.23 11.3 2.4 2.0 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Asp PF00026.23 EGF77675.1 - 4.9e-16 59.0 0.1 7e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77675.1 - 1.5e-05 24.9 0.2 0.00013 21.7 0.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Ribosomal_S18 PF01084.20 EGF77676.1 - 0.06 13.6 0.3 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 MICSWaP PF17018.5 EGF77676.1 - 0.15 11.6 1.0 0.18 11.3 0.1 1.5 2 0 0 2 2 2 0 Spore wall protein FtsH_ext PF06480.15 EGF77676.1 - 0.43 10.9 4.6 0.35 11.2 2.4 1.9 2 0 0 2 2 2 0 FtsH Extracellular Fzo_mitofusin PF04799.13 EGF77676.1 - 0.62 9.6 5.1 0.2 11.2 1.0 1.9 1 1 1 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.10 EGF77676.1 - 1.1 9.4 6.6 0.7 10.1 4.7 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 EGF77676.1 - 2.3 8.5 5.5 4.3 7.6 0.7 2.2 2 0 0 2 2 2 0 Haemolysin XhlA V-ATPase_G_2 PF16999.5 EGF77678.1 - 0.0041 17.5 2.6 0.099 13.1 2.7 2.4 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit D5_N PF08706.11 EGF77678.1 - 0.047 13.9 0.6 0.1 12.9 0.6 1.6 1 0 0 1 1 1 0 D5 N terminal like zf-SAP30 PF13866.6 EGF77678.1 - 0.056 13.6 5.2 1.4 9.1 0.0 3.3 3 0 0 3 3 3 0 SAP30 zinc-finger DUF4709 PF15821.5 EGF77678.1 - 0.18 12.1 6.2 0.18 12.1 2.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Phage_Mu_Gam PF07352.12 EGF77678.1 - 0.21 11.5 4.7 0.84 9.5 1.3 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Nbl1_Borealin_N PF10444.9 EGF77678.1 - 0.22 11.2 4.2 0.38 10.4 1.7 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Cep57_MT_bd PF06657.13 EGF77679.1 - 0.084 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 RRM_1 PF00076.22 EGF77681.1 - 3e-23 81.4 0.1 6.8e-12 45.0 0.0 2.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF77681.1 - 1.8e-11 43.7 0.0 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF77681.1 - 3.3e-07 30.1 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif NOA36 PF06524.12 EGF77681.1 - 0.17 11.2 3.7 0.25 10.6 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein HA2 PF04408.23 EGF77682.1 - 1.9e-24 86.0 0.0 4.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGF77682.1 - 1.2e-18 67.2 0.1 3.9e-18 65.6 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGF77682.1 - 1.9e-11 44.3 0.0 4.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGF77682.1 - 8.9e-10 38.6 0.2 1.8e-09 37.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF77682.1 - 7e-08 32.8 0.1 1.9e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGF77682.1 - 3.8e-05 23.4 0.1 0.00011 21.9 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGF77682.1 - 0.00031 21.1 0.1 0.00065 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF77682.1 - 0.001 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGF77682.1 - 0.0021 18.1 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EGF77682.1 - 0.0036 17.3 0.1 0.0075 16.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 EGF77682.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EGF77682.1 - 0.024 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EGF77682.1 - 0.025 14.0 0.1 0.15 11.5 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein AAA_7 PF12775.7 EGF77682.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGF77682.1 - 0.05 13.6 0.0 0.43 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGF77682.1 - 0.061 13.8 0.0 0.31 11.6 0.0 2.1 1 1 0 2 2 2 0 ABC transporter cobW PF02492.19 EGF77682.1 - 0.09 12.4 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EGF77682.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGF77682.1 - 0.14 11.9 0.0 5.3 6.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Dor1 PF04124.12 EGF77683.1 - 4.5e-75 252.4 0.4 6e-75 252.0 0.4 1.2 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 EGF77683.1 - 4.3e-06 26.7 0.2 1.1e-05 25.4 0.1 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Vps54_N PF10475.9 EGF77683.1 - 6e-06 25.8 0.2 9.6e-06 25.1 0.2 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 EGF77683.1 - 0.0018 16.9 0.1 0.0028 16.3 0.1 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 EzrA PF06160.12 EGF77683.1 - 0.085 11.0 0.1 0.12 10.6 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GSIII_N PF12437.8 EGF77686.1 - 2e-62 209.6 0.1 3.1e-62 209.0 0.1 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EGF77686.1 - 6.8e-37 125.9 0.0 1.3e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EGF77686.1 - 7.5e-21 74.5 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain EI24 PF07264.11 EGF77687.1 - 0.00092 19.5 0.0 0.0018 18.5 0.0 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF5527 PF17665.1 EGF77687.1 - 0.15 11.6 0.3 0.48 10.0 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Claudin_2 PF13903.6 EGF77687.1 - 0.19 11.4 6.6 0.25 11.1 4.2 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 EGF77687.1 - 0.61 10.0 9.0 1 9.2 9.0 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3671 PF12420.8 EGF77687.1 - 0.75 9.9 9.0 2 8.5 1.0 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF3611 PF12263.8 EGF77687.1 - 3.9 7.4 10.7 0.12 12.2 2.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) F-box PF00646.33 EGF77688.1 - 9.4e-05 22.2 0.5 0.00019 21.2 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGF77688.1 - 0.051 13.5 0.5 0.11 12.4 0.5 1.6 1 0 0 1 1 1 0 F-box-like Citrate_bind PF16114.5 EGF77689.1 - 4.1e-91 303.3 0.0 7.8e-91 302.4 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EGF77689.1 - 1.1e-18 67.5 1.0 2.4e-16 59.8 0.0 3.1 2 1 1 3 3 3 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGF77689.1 - 4.1e-15 55.9 0.2 9e-15 54.8 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EGF77689.1 - 1e-11 45.4 0.0 3.8e-11 43.5 0.0 2.1 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EGF77689.1 - 1.7e-06 27.7 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EGF77689.1 - 0.0025 17.6 0.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain LRR_4 PF12799.7 EGF77690.1 - 6.2e-22 77.3 21.1 2.5e-05 24.5 0.5 6.5 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF77690.1 - 7.8e-21 73.6 40.8 7.8e-08 32.0 3.1 5.2 2 2 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 EGF77690.1 - 1.2e-13 50.9 3.8 4.1e-12 45.9 0.4 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EGF77690.1 - 0.023 14.7 17.3 5.9 7.2 0.0 7.7 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 EGF77690.1 - 1.2 10.0 21.1 1.3e+02 3.8 0.0 8.3 5 4 1 6 6 6 0 Leucine Rich Repeat DUF2205 PF10224.9 EGF77691.1 - 6.5e-06 26.1 2.6 9.9e-06 25.5 0.8 2.2 2 0 0 2 2 2 1 Short coiled-coil protein Pyrid_oxidase_2 PF13883.6 EGF77691.1 - 0.0098 15.9 1.2 0.0098 15.9 1.2 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Ly49 PF08391.10 EGF77691.1 - 5.9 7.3 6.0 7 7.0 2.0 2.3 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Band_7 PF01145.25 EGF77692.1 - 1.3e-14 54.6 0.1 1.7e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7 PF01145.25 EGF77693.1 - 2.5e-30 105.8 0.5 5.2e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EGF77693.1 - 1.3e-26 92.4 0.4 4.1e-26 90.8 0.4 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 EGF77693.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Pox_A11 PF05061.13 EGF77693.1 - 0.1 11.9 0.7 0.16 11.2 0.7 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DivIVA PF05103.13 EGF77693.1 - 3 7.9 7.7 6.4 6.9 7.7 1.5 1 0 0 1 1 1 0 DivIVA protein baeRF_family6 PF18848.1 EGF77694.1 - 0.12 12.8 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 6 Zn_clus PF00172.18 EGF77695.1 - 1.2e-05 25.3 9.6 2.8e-05 24.2 9.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGF77695.1 - 0.0021 17.1 0.0 0.0021 17.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lipase_3 PF01764.25 EGF77696.1 - 9.9e-34 116.2 0.0 1.6e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGF77696.1 - 0.0011 18.5 0.0 0.0043 16.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGF77696.1 - 0.016 15.8 0.0 0.031 14.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF77696.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4179 PF13786.6 EGF77696.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Chromo_shadow PF01393.19 EGF77697.1 - 1.7e-20 72.8 1.2 7.8e-17 61.1 0.2 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGF77697.1 - 1.5e-14 53.6 0.6 1.5e-14 53.6 0.6 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tim17 PF02466.19 EGF77699.1 - 1.1e-05 25.8 7.7 2.4e-05 24.7 7.7 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4131 PF13567.6 EGF77699.1 - 0.16 11.6 1.0 0.48 10.1 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ThrE_2 PF12821.7 EGF77699.1 - 0.48 10.6 3.7 0.71 10.0 3.7 1.4 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE WD40 PF00400.32 EGF77700.1 - 5.1e-44 147.4 33.3 9e-09 35.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77700.1 - 7.2e-16 58.3 6.9 1.2e-05 25.5 0.1 5.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF77700.1 - 1.5e-05 25.0 1.4 0.009 15.9 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGF77700.1 - 0.00043 18.4 6.0 0.053 11.5 0.2 2.3 1 1 0 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 EGF77700.1 - 0.0042 16.1 7.9 0.19 10.7 0.3 4.3 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2387 PF09526.10 EGF77700.1 - 9.2 6.5 7.6 34 4.7 0.1 3.8 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) LCE PF14672.6 EGF77701.1 - 1.6 9.4 16.7 0.07 13.7 9.7 2.2 2 0 0 2 2 2 0 Late cornified envelope Epimerase PF01370.21 EGF77702.1 - 1.1e-14 54.5 0.2 1.3e-13 51.0 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGF77702.1 - 3.5e-12 46.6 0.0 1.6e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EGF77702.1 - 1.7e-11 44.1 0.0 3.3e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EGF77702.1 - 1.8e-10 40.3 0.0 2.2e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGF77702.1 - 3.2e-10 39.6 0.0 1.1e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGF77702.1 - 0.00016 21.2 0.2 0.0018 17.8 0.1 2.4 2 1 1 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGF77702.1 - 0.0011 18.2 0.4 0.73 9.0 0.1 2.8 1 1 1 3 3 3 2 Male sterility protein adh_short PF00106.25 EGF77702.1 - 0.06 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pept_tRNA_hydro PF01195.19 EGF77703.1 - 6.6e-18 65.3 0.0 1.4e-17 64.2 0.0 1.5 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase HMG_box PF00505.19 EGF77704.1 - 4.5e-15 55.8 1.5 2.6e-13 50.2 1.5 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF77704.1 - 1.6e-10 41.4 0.6 2e-10 41.1 0.6 1.1 1 0 0 1 1 1 1 HMG-box domain MlaC PF05494.12 EGF77704.1 - 0.013 15.2 0.2 0.014 15.1 0.2 1.2 1 1 0 1 1 1 0 MlaC protein DUF3782 PF12644.7 EGF77704.1 - 0.035 14.3 0.2 0.046 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) AXE1 PF05448.12 EGF77704.1 - 0.05 12.3 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) GDP_Man_Dehyd PF16363.5 EGF77705.1 - 4e-58 197.4 0.0 1.5e-57 195.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGF77705.1 - 3.1e-47 161.0 0.0 3.9e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF77705.1 - 1.6e-12 47.0 0.0 2.2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGF77705.1 - 1.4e-10 40.8 0.2 6e-06 25.6 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGF77705.1 - 2.3e-10 40.1 0.1 6.1e-06 25.6 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EGF77705.1 - 7.4e-10 38.4 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EGF77705.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 EGF77705.1 - 0.19 11.6 0.0 0.47 10.3 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Pkinase PF00069.25 EGF77706.1 - 4.7e-67 226.1 0.0 5.3e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77706.1 - 7.1e-40 136.9 0.0 8.9e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77706.1 - 0.00052 18.9 0.0 0.00079 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGF77706.1 - 0.0059 15.7 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGF77706.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EGF77706.1 - 0.019 14.5 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGF77706.1 - 0.039 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF77706.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 EGF77708.1 - 6.7e-67 225.6 0.0 8.2e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77708.1 - 4.6e-27 94.9 0.0 8.1e-27 94.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77708.1 - 1.4e-06 27.9 0.0 0.00031 20.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EGF77708.1 - 0.0055 15.7 0.1 0.013 14.5 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF77708.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGF77708.1 - 0.034 13.5 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm7 PF15585.6 EGF77708.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 NIF3 PF01784.18 EGF77709.1 - 3.7e-64 216.7 0.0 4.6e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4777 PF16007.5 EGF77709.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Rft-1 PF04506.13 EGF77711.1 - 5.8e-105 352.0 29.7 6.7e-105 351.7 29.7 1.0 1 0 0 1 1 1 1 Rft protein Gp_dh_C PF02800.20 EGF77712.1 - 2.6e-67 225.3 0.1 3.6e-67 224.9 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGF77712.1 - 8.5e-37 125.6 0.1 2.4e-36 124.1 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DGCR6 PF07324.11 EGF77713.1 - 1.7e-07 31.1 2.8 4.2e-07 29.8 2.8 1.6 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 EGF77713.1 - 1.4e-05 24.8 2.6 2.5e-05 24.0 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) GEMIN8 PF15348.6 EGF77713.1 - 0.032 14.5 7.0 0.043 14.1 7.0 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 TFIIA PF03153.13 EGF77713.1 - 0.51 10.3 16.7 0.65 9.9 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_9 PF14580.6 EGF77714.1 - 4.2e-19 68.7 7.6 1.2e-16 60.7 6.6 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EGF77714.1 - 6e-17 61.5 47.7 9.5e-07 29.0 0.6 5.1 2 1 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF77714.1 - 1.9e-10 40.3 33.8 2.2e-06 27.3 1.4 4.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 EGF77714.1 - 0.022 14.8 0.1 0.022 14.8 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich repeat GIDA_assoc PF13932.6 EGF77714.1 - 0.039 14.2 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 GidA associated domain WD40 PF00400.32 EGF77715.1 - 7.4e-16 58.3 22.1 0.00056 20.7 1.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77715.1 - 0.00035 20.8 0.1 1.3 9.4 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGF77715.1 - 0.019 15.5 0.1 20 5.8 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain PALB2_WD40 PF16756.5 EGF77715.1 - 0.079 11.9 0.3 4.7 6.0 0.1 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain UQ_con PF00179.26 EGF77716.1 - 1.6e-44 150.9 0.0 2.1e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 EGF77716.1 - 1.2e-13 50.7 0.1 2e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 EGF77716.1 - 2.5e-05 24.0 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EGF77716.1 - 0.00023 20.9 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGF77716.1 - 0.025 14.9 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 RWD domain RibD_C PF01872.17 EGF77717.1 - 4.9e-31 108.1 0.0 5.5e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Ribosomal_S3_C PF00189.20 EGF77718.1 - 8.6e-25 87.1 0.4 3.5e-24 85.1 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGF77718.1 - 4.6e-13 48.8 0.4 8e-13 48.0 0.4 1.4 1 0 0 1 1 1 1 KH domain DUF1746 PF08508.10 EGF77719.1 - 9.9e-07 29.1 8.4 3.4e-06 27.4 8.4 1.8 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Mis14 PF08641.12 EGF77720.1 - 3.4e-08 33.9 6.9 6.8e-08 32.9 1.6 2.5 2 0 0 2 2 2 2 Kinetochore protein Mis14 like EPSP_synthase PF00275.20 EGF77721.1 - 1e-121 406.6 0.1 1.6e-121 406.0 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EGF77721.1 - 2.3e-98 328.5 0.0 4e-98 327.7 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EGF77721.1 - 3e-50 171.6 0.0 6.2e-50 170.6 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EGF77721.1 - 2.1e-30 106.0 0.0 2.8e-29 102.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EGF77721.1 - 1.2e-18 67.1 0.0 4.4e-18 65.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGF77721.1 - 3.9e-09 36.1 0.2 1.7e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EGF77721.1 - 2.9e-05 24.1 0.0 8.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 EGF77721.1 - 0.00043 20.1 2.4 0.0038 17.0 2.4 2.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Sacchrp_dh_NADP PF03435.18 EGF77721.1 - 0.0022 18.2 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 EGF77721.1 - 0.0075 16.7 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain OCD_Mu_crystall PF02423.15 EGF77721.1 - 0.011 14.7 0.1 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AAA PF00004.29 EGF77721.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF77721.1 - 0.07 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain HTH_37 PF13744.6 EGF77721.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DUF815 PF05673.13 EGF77721.1 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pkinase PF00069.25 EGF77722.1 - 1.3e-63 214.9 0.0 1.6e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77722.1 - 1.4e-30 106.5 0.0 1.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF77722.1 - 6.1e-05 22.1 0.1 8.2e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGF77722.1 - 0.00013 21.4 0.0 0.00027 20.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF77722.1 - 0.0091 15.9 0.1 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF77722.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGF77722.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Phosphorylase PF00343.20 EGF77723.1 - 0 1033.8 0.0 0 1033.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3417 PF11897.8 EGF77723.1 - 0.091 13.2 0.6 0.21 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF2870 PF11069.8 EGF77724.1 - 2e-43 146.7 3.9 3.2e-43 146.0 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) HSBP1 PF06825.12 EGF77725.1 - 7.5e-20 70.5 1.4 1.3e-19 69.8 1.4 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Erythro-docking PF09277.11 EGF77725.1 - 0.005 16.7 0.2 0.095 12.6 0.1 2.6 2 1 1 3 3 3 1 Erythronolide synthase, docking Baculo_PEP_C PF04513.12 EGF77725.1 - 0.025 14.6 0.1 0.029 14.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 EGF77725.1 - 0.067 13.1 1.0 0.64 9.9 1.0 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CLZ PF16526.5 EGF77725.1 - 0.075 13.4 1.9 0.1 13.0 1.4 1.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RhoGAP PF00620.27 EGF77726.1 - 4.7e-32 110.9 0.0 1.5e-31 109.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.17 EGF77726.1 - 1.4e-24 86.7 0.0 3e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.26 EGF77726.1 - 0.0007 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 WW domain IQ PF00612.27 EGF77727.1 - 8e-12 43.9 47.7 0.0018 17.9 0.1 8.6 8 0 0 8 8 8 6 IQ calmodulin-binding motif SPRY PF00622.28 EGF77727.1 - 0.00022 21.3 0.0 0.0006 19.9 0.0 1.7 2 0 0 2 2 2 1 SPRY domain Carn_acyltransf PF00755.20 EGF77729.1 - 3.5e-177 590.6 0.0 4e-177 590.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Urease_linker PF18473.1 EGF77729.1 - 0.13 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain Myosin_head PF00063.21 EGF77730.1 - 1.3e-224 747.3 1.5 2e-224 746.8 1.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGF77730.1 - 1e-43 149.2 2.0 1.8e-43 148.4 2.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 EGF77730.1 - 5.6e-18 64.5 0.1 1.1e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF77730.1 - 5.2e-17 61.2 0.0 9.5e-17 60.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF77730.1 - 2.7e-15 55.8 0.0 5.8e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 EGF77730.1 - 0.011 16.0 0.1 0.15 12.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain IQ PF00612.27 EGF77730.1 - 0.02 14.6 3.6 0.051 13.4 3.6 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Androgen_recep PF02166.16 EGF77730.1 - 0.029 13.2 4.4 0.047 12.5 4.4 1.3 1 0 0 1 1 1 0 Androgen receptor DLP_helical PF18709.1 EGF77730.1 - 0.041 13.1 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Dynamin-like helical domain AAA_16 PF13191.6 EGF77730.1 - 0.061 13.7 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TFIIA PF03153.13 EGF77730.1 - 1.7 8.6 12.3 3.2 7.7 12.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran PF00005.27 EGF77730.1 - 2.3 8.7 5.7 1.4 9.4 0.1 2.9 3 0 0 3 3 3 0 ABC transporter Sod_Fe_C PF02777.18 EGF77731.1 - 3e-38 130.1 0.2 5.2e-38 129.3 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGF77731.1 - 7.6e-33 112.8 2.1 1.8e-32 111.6 2.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain LRR_4 PF12799.7 EGF77732.1 - 1e-13 51.2 11.8 2.9e-08 33.9 0.5 4.5 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF77732.1 - 9.8e-09 34.9 2.4 1.3e-07 31.2 0.6 2.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 EGF77732.1 - 1.4e-08 34.4 4.1 4.6e-07 29.5 1.8 3.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 EGF77732.1 - 0.00011 22.0 1.5 1.6 8.9 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 EGF77732.1 - 0.0005 20.2 4.3 11 7.0 0.1 5.3 4 0 0 4 4 4 2 Leucine Rich Repeat Ala_racemase_N PF01168.20 EGF77736.1 - 4.2e-20 72.3 0.0 4.8e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.16 EGF77736.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase II Tfb5 PF06331.12 EGF77737.1 - 2.6e-20 72.2 1.4 2.8e-20 72.1 1.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Baculo_IE-1 PF05290.11 EGF77737.1 - 0.19 11.7 0.1 0.22 11.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) ubiquitin PF00240.23 EGF77738.1 - 3.9e-08 32.9 0.0 6.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 EGF77738.1 - 3e-06 27.1 19.0 1.9e-05 24.5 3.7 3.6 3 1 1 4 4 4 2 STI1 domain UBA PF00627.31 EGF77738.1 - 4.6e-06 26.4 1.0 1e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.9 EGF77738.1 - 0.0003 21.3 0.0 0.00057 20.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGF77738.1 - 0.084 13.0 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 EGF77738.1 - 4.4 7.1 18.6 1.1 9.0 1.8 3.8 2 1 1 3 3 3 0 XPC-binding domain RPA43_OB PF17875.1 EGF77739.1 - 1.5e-11 45.0 3.8 1.6e-10 41.7 0.0 2.9 2 1 1 3 3 3 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EGF77739.1 - 5.8e-10 39.4 0.2 2.1e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 F-box-like PF12937.7 EGF77740.1 - 2.6e-09 36.8 1.5 1.2e-08 34.7 1.5 2.2 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 EGF77740.1 - 3.5e-07 30.2 12.0 7.1e-07 29.2 12.0 1.6 1 0 0 1 1 1 1 MYND finger F-box PF00646.33 EGF77740.1 - 0.12 12.3 3.6 2.2 8.2 3.6 2.6 1 1 0 1 1 1 0 F-box domain CCDC14 PF15254.6 EGF77741.1 - 0.027 13.1 2.8 0.034 12.8 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 TUG-UBL1 PF11470.8 EGF77742.1 - 1.4e-18 66.8 0.3 3.2e-18 65.7 0.3 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 EGF77742.1 - 6.9e-09 35.8 0.0 7.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 UBX domain Cobl PF09469.10 EGF77742.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain COX7a PF02238.15 EGF77744.1 - 0.82 10.1 2.9 2.7 8.5 0.1 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII LRR_4 PF12799.7 EGF77745.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) CK_II_beta PF01214.18 EGF77746.1 - 9.8e-64 214.5 0.0 1.2e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4746 PF15928.5 EGF77746.1 - 0.05 13.0 0.1 0.072 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIF_beta PF02270.15 EGF77747.1 - 3.3e-23 81.6 0.0 5.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EGF77747.1 - 1.2e-21 77.9 0.3 2.2e-21 77.0 0.3 1.6 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 EGF77747.1 - 0.0034 18.2 0.7 0.0066 17.3 0.7 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Leo1 PF04004.13 EGF77747.1 - 0.0089 15.9 0.3 0.031 14.1 0.1 1.9 2 0 0 2 2 2 1 Leo1-like protein MRP-S26 PF14943.6 EGF77747.1 - 0.037 13.9 0.5 0.058 13.3 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 CdhD PF03599.16 EGF77747.1 - 0.065 11.9 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Cation_ATPase_C PF00689.21 EGF77750.1 - 1.3e-42 145.6 9.3 1.3e-42 145.6 9.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGF77750.1 - 3.4e-35 121.2 0.6 3.4e-35 121.2 0.6 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGF77750.1 - 2.3e-19 69.3 0.0 5.7e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGF77750.1 - 1.3e-16 61.5 0.1 8.5e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF77750.1 - 6.2e-06 25.8 0.0 6.9e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF77750.1 - 0.00068 19.4 0.4 0.006 16.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4173 PF13777.6 EGF77750.1 - 4.2 6.8 9.5 0.75 9.2 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) EMP24_GP25L PF01105.24 EGF77751.1 - 1.3e-38 132.7 0.4 1.5e-38 132.5 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3732 PF12532.8 EGF77751.1 - 0.029 13.9 0.1 0.043 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) SdrD_B PF17210.3 EGF77751.1 - 0.1 12.8 0.1 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 SdrD B-like domain SWIRM PF04433.17 EGF77752.1 - 7.9e-30 103.0 0.1 1.7e-29 102.0 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGF77752.1 - 3.1e-26 91.1 9.6 5.2e-26 90.4 9.6 1.4 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGF77752.1 - 1.4e-12 47.5 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF77752.1 - 2e-07 31.2 0.0 4.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGF77752.1 - 2.8e-05 23.8 5.2 5.3e-05 22.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EGF77752.1 - 0.0092 16.3 2.5 0.016 15.5 2.5 1.5 1 0 0 1 1 1 1 C1 domain DUF4764 PF15961.5 EGF77752.1 - 0.05 12.3 0.1 0.24 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) HypA PF01155.19 EGF77752.1 - 0.49 10.4 3.1 0.57 10.2 1.1 2.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Chordopox_RPO7 PF05864.12 EGF77752.1 - 1 9.7 4.8 0.17 12.1 0.8 1.8 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ASH PF15780.5 EGF77753.1 - 5.8e-19 68.1 13.8 0.00094 19.3 0.2 9.7 10 1 1 11 11 11 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EGF77753.1 - 6.7e-07 29.3 8.1 0.29 11.2 0.0 7.7 8 0 0 8 8 8 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 EGF77753.1 - 3e-06 27.3 1.3 3.1 8.0 0.0 6.5 6 0 0 6 6 6 2 Flagellar-associated PapD-like MYCBPAP PF14646.6 EGF77753.1 - 0.011 14.7 0.1 0.24 10.3 0.0 2.9 3 0 0 3 3 3 0 MYCBP-associated protein family fn3_5 PF06280.12 EGF77753.1 - 0.11 13.2 2.4 4.2 8.1 0.0 4.4 4 0 0 4 4 4 0 Fn3-like domain PH PF00169.29 EGF77754.1 - 0.027 15.0 0.1 0.068 13.7 0.0 1.7 2 0 0 2 2 2 0 PH domain DUF2423 PF10338.9 EGF77755.1 - 5.7e-14 52.1 3.4 5.7e-14 52.1 3.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Cullin PF00888.22 EGF77757.1 - 1.5e-184 615.1 8.6 1.5e-184 615.1 8.6 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGF77757.1 - 6.6e-27 93.3 4.1 1.9e-26 91.9 4.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EGF77757.1 - 0.033 14.5 2.4 0.1 13.0 0.2 2.8 3 0 0 3 3 3 0 Penicillinase repressor DUF1722 PF08349.11 EGF77757.1 - 0.5 10.7 5.6 0.84 9.9 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) DEAD PF00270.29 EGF77759.1 - 1.2e-38 132.6 0.0 2.5e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF77759.1 - 1.6e-25 89.6 0.2 1.5e-23 83.2 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF77759.1 - 2e-08 34.4 0.1 1.9e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGF77759.1 - 0.00017 20.9 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Thioredoxin PF00085.20 EGF77760.1 - 4.4e-63 209.7 0.0 4.8e-32 110.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGF77760.1 - 3.1e-21 76.1 0.1 1.1e-20 74.3 0.1 2.0 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EGF77760.1 - 1.2e-15 57.6 0.0 7.7e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGF77760.1 - 2.7e-13 50.3 0.3 5.4e-05 23.6 0.1 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EGF77760.1 - 2.5e-08 33.9 0.1 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EGF77760.1 - 9.8e-08 32.2 0.2 0.033 14.5 0.0 3.7 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EGF77760.1 - 1.1e-07 31.9 0.0 0.00034 20.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.6 EGF77760.1 - 3.2e-05 23.9 0.1 0.0019 18.1 0.1 2.9 1 1 1 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 EGF77760.1 - 6.4e-05 22.9 0.0 1.2 9.1 0.0 3.3 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EGF77760.1 - 8.2e-05 22.3 0.6 0.21 11.3 0.1 2.3 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 EGF77760.1 - 0.00042 20.2 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGF77760.1 - 0.0012 18.6 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin DDE_Tnp_1_2 PF13586.6 EGF77760.1 - 0.0015 18.8 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain Thioredoxin_4 PF13462.6 EGF77760.1 - 0.022 14.9 0.2 2.9 8.0 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin TPR_11 PF13414.6 EGF77761.1 - 7.2e-11 41.6 0.6 1.6e-05 24.5 0.1 2.9 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 EGF77761.1 - 5.6e-10 38.6 0.4 0.00058 19.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF77761.1 - 5.8e-09 36.5 0.2 1e-05 26.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF77761.1 - 6.5e-07 29.0 0.2 0.0046 17.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 EGF77761.1 - 7.6e-05 23.7 0.3 0.0012 19.8 0.0 3.1 2 1 0 2 2 2 1 CS domain TPR_17 PF13431.6 EGF77761.1 - 0.0002 21.5 2.8 0.027 14.8 0.2 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF77761.1 - 0.0013 19.1 2.1 0.12 12.8 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF77761.1 - 0.0015 19.1 1.5 1.3 10.1 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF77761.1 - 0.0025 17.9 0.0 1.2 9.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat BDHCT_assoc PF16204.5 EGF77761.1 - 0.0043 16.8 0.8 0.008 15.9 0.8 1.4 1 0 0 1 1 1 1 BDHCT-box associated domain on Bloom syndrome protein TPR_9 PF13371.6 EGF77761.1 - 0.0049 17.0 2.0 3.8 7.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat FYTT PF07078.11 EGF77761.1 - 0.11 11.8 3.8 0.068 12.5 1.7 1.6 2 0 0 2 2 2 0 Forty-two-three protein MatP PF06303.12 EGF77761.1 - 5.8 7.5 8.0 3.8 8.1 4.3 2.3 2 0 0 2 2 2 0 MatP N-terminal domain Pkinase PF00069.25 EGF77762.1 - 7.4e-59 199.3 0.0 9.9e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77762.1 - 1.3e-43 149.2 0.0 1.8e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77762.1 - 2.4e-07 30.4 0.0 5e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF77762.1 - 6e-07 28.6 0.0 1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF77762.1 - 0.0027 17.7 0.0 0.0054 16.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF77762.1 - 0.062 12.2 0.2 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 EGF77762.1 - 0.14 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Eaf7 PF07904.13 EGF77763.1 - 2.4e-18 66.4 0.1 5.4e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 TEA PF01285.18 EGF77763.1 - 0.021 14.9 0.1 0.07 13.2 0.0 1.9 2 0 0 2 2 2 0 TEA/ATTS domain HECT PF00632.25 EGF77764.1 - 1.1e-82 278.0 0.0 1.2e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) EI24 PF07264.11 EGF77765.1 - 7.4e-19 68.7 15.7 7.4e-19 68.7 15.7 1.8 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) UBX PF00789.20 EGF77766.1 - 1.8e-19 69.7 0.0 2e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 EGF77766.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain HalOD2 PF18547.1 EGF77766.1 - 0.099 12.6 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Halobacterial output domain 2 Borrelia_P83 PF05262.11 EGF77766.1 - 6.8 5.1 23.2 8.5 4.7 23.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LCD1 PF09798.9 EGF77766.1 - 9.6 4.6 12.9 12 4.3 12.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein 2-Hacid_dh_C PF02826.19 EGF77767.1 - 8.4e-39 132.8 0.0 1.2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGF77767.1 - 2.3e-06 27.3 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGF77767.1 - 9.8e-05 22.6 0.2 0.0004 20.6 0.1 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Tau95 PF09734.9 EGF77768.1 - 1.9e-33 116.2 1.0 5.2e-33 114.8 1.0 1.8 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EGF77768.1 - 1.3e-20 73.9 0.0 1.2e-19 70.8 0.0 2.5 1 1 0 1 1 1 1 Tau95 Triple barrel domain TFIIF_beta PF02270.15 EGF77768.1 - 0.0064 16.6 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Ubie_methyltran PF01209.18 EGF77769.1 - 4.2e-79 265.2 0.0 4.9e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGF77769.1 - 3.7e-16 59.6 0.0 1.2e-15 57.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF77769.1 - 6.2e-15 55.6 0.0 1.2e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF77769.1 - 2.4e-14 53.4 0.0 3.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF77769.1 - 1.3e-08 35.5 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF77769.1 - 3.5e-06 26.9 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EGF77769.1 - 0.0011 18.6 0.0 0.022 14.3 0.0 2.1 1 1 1 2 2 2 1 MraW methylase family Methyltransf_8 PF05148.15 EGF77769.1 - 0.0099 15.7 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EGF77769.1 - 0.034 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 EGF77769.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_28 PF02636.17 EGF77769.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CPSase_L_D2 PF02786.17 EGF77770.1 - 8.7e-79 263.9 0.2 1.5e-78 263.2 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGF77770.1 - 7.6e-44 148.8 0.2 2.8e-43 146.9 0.1 2.1 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGF77770.1 - 2.5e-33 114.4 0.0 2.6e-32 111.1 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 EGF77770.1 - 3.2e-31 108.3 0.0 1.1e-30 106.6 0.0 1.9 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 EGF77770.1 - 3.3e-15 55.7 3.3 8.7e-15 54.3 3.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGF77770.1 - 7.2e-09 35.5 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGF77770.1 - 2.3e-08 33.8 0.0 5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGF77770.1 - 0.00046 20.9 0.6 1.4 9.7 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 EGF77770.1 - 0.0015 18.6 0.1 0.0034 17.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGF77770.1 - 0.0039 17.0 0.1 0.0094 15.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EGF77770.1 - 0.016 14.7 1.1 0.61 9.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGF77770.1 - 0.022 14.6 4.9 0.68 9.8 0.1 2.9 2 1 1 3 3 3 0 Biotin-lipoyl like RnfC_N PF13375.6 EGF77770.1 - 0.034 14.1 2.8 0.04 13.9 0.3 2.5 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EGF77770.1 - 0.05 13.5 2.0 0.092 12.6 0.3 2.1 2 0 0 2 2 2 0 Glycine cleavage H-protein Meth_synt_2 PF01717.18 EGF77771.1 - 2.3e-153 510.2 0.0 4.2e-146 486.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGF77771.1 - 4.1e-113 378.0 0.0 1e-105 353.7 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGF77771.1 - 0.027 13.6 0.1 0.22 10.6 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Ank_2 PF12796.7 EGF77772.1 - 1.6e-13 51.0 1.1 4.6e-05 23.9 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF77772.1 - 1.9e-13 50.6 2.1 4.6e-05 23.9 0.1 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF77772.1 - 1.6e-11 44.2 2.2 4.4e-06 26.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF77772.1 - 8.8e-11 41.7 1.2 0.0047 17.3 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EGF77772.1 - 3e-09 36.3 1.4 0.0054 17.1 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat ZapB PF06005.12 EGF77772.1 - 0.0023 18.3 4.3 0.0059 17.0 4.3 1.7 1 0 0 1 1 1 1 Cell division protein ZapB KilA-N PF04383.13 EGF77772.1 - 0.0053 16.6 0.2 0.038 13.8 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain Shisa PF13908.6 EGF77773.1 - 0.0011 19.2 0.7 0.0011 19.2 0.7 1.8 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator CD20 PF04103.15 EGF77773.1 - 0.029 14.5 0.1 0.029 14.5 0.1 1.5 2 0 0 2 2 2 0 CD20-like family C1ORF64 PF15547.6 EGF77773.1 - 0.17 12.3 4.9 0.082 13.4 2.8 1.5 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein ParA PF10609.9 EGF77774.1 - 1.3e-83 280.2 0.1 1.4e-53 181.8 0.0 2.0 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGF77774.1 - 4.4e-12 46.2 0.0 1.1e-11 44.9 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGF77774.1 - 7.7e-10 39.0 0.3 5.5e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EGF77774.1 - 1.9e-08 33.9 0.3 3.4e-07 29.8 0.3 2.1 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EGF77774.1 - 2.6e-07 30.1 1.3 5.2e-06 25.9 0.5 2.4 1 1 1 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EGF77774.1 - 7.4e-05 21.9 0.2 0.00011 21.3 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EGF77774.1 - 0.00033 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 EGF77774.1 - 0.00051 19.9 0.0 0.086 12.6 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 EGF77774.1 - 0.00088 18.9 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EGF77774.1 - 0.004 17.1 0.1 0.0067 16.3 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase CBP_BcsQ PF06564.12 EGF77774.1 - 0.0047 16.4 0.2 0.026 14.0 0.3 1.8 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGF77774.1 - 0.0079 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 EGF77774.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EGF77774.1 - 0.025 14.9 0.2 0.043 14.2 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain VirC1 PF07015.11 EGF77774.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein AAA_26 PF13500.6 EGF77774.1 - 0.033 14.0 0.2 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGF77774.1 - 0.067 13.1 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_33 PF13671.6 EGF77774.1 - 0.068 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGF77774.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGF77774.1 - 0.094 13.0 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGF77774.1 - 0.1 12.5 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EGF77774.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EGF77774.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 EGF77774.1 - 0.15 12.6 0.5 0.25 11.9 0.5 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF77774.1 - 0.15 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGF77774.1 - 0.17 11.6 0.2 0.24 11.1 0.2 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGF77774.1 - 0.17 11.7 0.2 0.33 10.8 0.2 1.4 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 EGF77774.1 - 0.19 10.9 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain PigN PF04987.14 EGF77775.1 - 7.2e-138 460.3 48.2 9.5e-138 459.9 48.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGF77775.1 - 1.1e-10 41.6 0.8 8.5e-10 38.7 0.8 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Peptidase_C48 PF02902.19 EGF77776.1 - 6.8e-15 55.5 0.2 3.3e-14 53.3 0.2 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DnaJ_C PF01556.18 EGF77777.1 - 2e-34 118.8 0.1 2.7e-34 118.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGF77777.1 - 3.3e-24 84.8 3.8 6.1e-24 83.9 3.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGF77777.1 - 2e-15 56.9 14.4 3.3e-15 56.2 14.4 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EGF77777.1 - 3.2e-06 27.2 4.1 0.0064 16.5 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EGF77777.1 - 3.1e-05 23.9 6.9 0.0052 16.7 0.7 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EGF77777.1 - 0.59 9.8 10.3 1.8 8.2 0.7 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 EGF77777.1 - 1.6 8.8 8.5 3.4 7.8 8.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 EGF77777.1 - 2.5 8.3 8.3 0.79 9.9 3.5 2.2 1 1 2 3 3 3 0 zinc RING finger of MSL2 FdhE PF04216.12 EGF77777.1 - 7.5 6.3 6.7 8 6.2 5.5 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation zinc_ribbon_9 PF14369.6 EGF77777.1 - 7.7 6.9 8.5 13 6.2 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon Sin_N PF04801.13 EGF77778.1 - 3.5e-79 267.0 2.2 1.3e-76 258.6 0.2 2.3 1 1 1 2 2 2 2 Sin-like protein conserved region zf-LYAR PF08790.11 EGF77779.1 - 1.9e-15 56.4 5.0 1.9e-15 56.4 5.0 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EGF77779.1 - 0.024 14.2 1.5 1.4 8.6 0.5 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-TRAF PF02176.18 EGF77779.1 - 0.047 14.4 2.5 0.09 13.5 2.5 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger FancD2 PF14631.6 EGF77779.1 - 0.49 7.7 9.2 0.55 7.6 9.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-ACC PF17848.1 EGF77779.1 - 2 8.6 6.2 0.19 11.8 1.4 1.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2 PF00096.26 EGF77779.1 - 2.4 8.8 5.8 7 7.3 0.4 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type Arrestin_N PF00339.29 EGF77780.1 - 0.039 14.0 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain AAA PF00004.29 EGF77781.1 - 1.5e-41 141.9 0.0 2.6e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF77781.1 - 3.7e-10 39.5 0.8 6.5e-10 38.7 0.8 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGF77781.1 - 1.3e-08 34.7 0.1 2.6e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EGF77781.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGF77781.1 - 1.7e-05 25.1 0.3 0.011 15.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGF77781.1 - 5.6e-05 22.4 0.0 9.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGF77781.1 - 0.00016 22.1 0.3 0.005 17.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGF77781.1 - 0.0002 21.4 0.2 0.0011 18.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGF77781.1 - 0.00065 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGF77781.1 - 0.0054 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGF77781.1 - 0.0064 15.9 0.3 0.27 10.6 0.1 2.6 2 1 1 3 3 3 1 KaiC AAA_18 PF13238.6 EGF77781.1 - 0.0072 16.9 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGF77781.1 - 0.0076 16.1 0.1 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGF77781.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EGF77781.1 - 0.036 14.3 0.1 0.093 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EGF77781.1 - 0.036 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGF77781.1 - 0.083 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF2075 PF09848.9 EGF77781.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EGF77781.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGF77781.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGF77781.1 - 0.14 11.9 0.3 0.37 10.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGF77781.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGF77781.1 - 0.16 11.9 0.2 0.78 9.6 0.1 2.1 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGF77781.1 - 0.19 11.4 0.4 0.41 10.3 0.4 1.6 1 1 0 1 1 1 0 AAA domain Amino_oxidase PF01593.24 EGF77782.1 - 1.7e-39 136.4 0.0 2e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase RNase_PH PF01138.21 EGF77783.1 - 5e-16 59.4 0.1 2.8e-15 57.0 0.1 2.3 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGF77783.1 - 9e-11 41.7 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pex2_Pex12 PF04757.14 EGF77784.1 - 3.8e-29 101.9 4.9 5.1e-29 101.5 4.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGF77784.1 - 1.1e-09 38.0 10.5 1.6e-09 37.4 10.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF77784.1 - 4.1e-09 36.6 13.1 6.3e-09 36.0 13.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF77784.1 - 3.8e-08 33.0 12.3 6e-08 32.4 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF77784.1 - 5.6e-08 32.5 11.0 8.8e-08 31.9 11.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF77784.1 - 1.2e-07 31.4 9.1 1.9e-07 30.8 9.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGF77784.1 - 9.1e-05 22.7 10.2 0.00016 21.9 10.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGF77784.1 - 0.00015 21.7 11.1 0.00025 20.9 11.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF77784.1 - 0.00019 21.4 6.4 0.00019 21.4 6.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGF77784.1 - 0.086 13.0 10.5 0.17 12.0 10.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGF77784.1 - 0.091 12.9 8.4 0.2 11.8 8.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EGF77784.1 - 0.28 11.1 3.6 0.5 10.3 3.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EGF77784.1 - 0.42 10.4 5.4 0.14 12.0 2.2 1.9 2 0 0 2 2 2 0 RING-like zinc finger Tim17 PF02466.19 EGF77785.1 - 1.4e-18 67.2 3.2 1.9e-18 66.8 2.8 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Torus PF16131.5 EGF77786.1 - 1.5e-31 109.3 1.5 3.6e-31 108.1 1.5 1.7 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EGF77786.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGF77786.1 - 0.076 13.1 6.3 0.18 11.9 6.3 1.7 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 EGF77786.1 - 1.1 9.2 7.9 1.9 8.4 7.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 EGF77786.1 - 3.4 7.7 6.7 7.7 6.6 6.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UMP1 PF05348.11 EGF77787.1 - 2.1e-32 111.8 0.3 2.4e-32 111.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 KH_1 PF00013.29 EGF77790.1 - 0.00024 20.9 1.3 0.0005 19.8 1.3 1.5 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 EGF77790.1 - 0.0009 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_4 PF13083.6 EGF77790.1 - 0.047 13.6 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 KH domain VID27 PF08553.10 EGF77791.1 - 4.2e-156 519.5 0.2 7.5e-156 518.6 0.2 1.4 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EGF77791.1 - 6.4e-60 201.9 12.5 2.8e-58 196.6 0.0 4.1 3 1 1 4 4 4 2 VID27 N-terminal region VID27_PH PF17747.1 EGF77791.1 - 1.6e-27 95.9 1.5 7.8e-27 93.7 1.4 2.1 2 0 0 2 2 2 1 VID27 PH-like domain FGF-BP1 PF06473.12 EGF77791.1 - 0.11 12.4 1.4 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Trypan_PARP PF05887.11 EGF77793.1 - 0.0099 15.9 1.6 0.012 15.6 1.6 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.13 EGF77793.1 - 0.41 9.6 2.8 0.4 9.6 2.8 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Neisseria_TspB PF05616.13 EGF77793.1 - 0.58 8.6 3.7 0.6 8.5 3.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Nup_retrotrp_bd PF10599.9 EGF77794.1 - 0.19 12.4 3.9 0.47 11.1 3.9 1.6 1 0 0 1 1 1 0 Retro-transposon transporting motif RabGAP-TBC PF00566.18 EGF77795.1 - 1.3e-58 198.2 0.3 1.3e-58 198.2 0.3 2.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF4559 PF15112.6 EGF77795.1 - 0.0035 17.1 12.7 0.006 16.3 12.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) LPD5 PF18799.1 EGF77795.1 - 0.025 15.0 1.6 0.025 15.0 1.6 1.9 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 5 FAS_I_H PF18314.1 EGF77795.1 - 0.029 14.0 4.3 1 8.9 1.8 2.9 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain SRP68 PF16969.5 EGF77796.1 - 4.2e-127 425.5 9.3 5.1e-127 425.2 9.3 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 EGF77796.1 - 0.14 12.3 3.7 9.7 6.6 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF77796.1 - 0.25 11.6 5.5 3.1 8.1 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EGF77797.1 - 4.3e-41 141.0 0.0 1.2e-21 77.2 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77797.1 - 2.4e-15 56.6 0.0 9.7e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77797.1 - 0.12 11.1 0.2 0.34 9.6 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase RPA_interact_N PF14766.6 EGF77798.1 - 7.1e-08 32.0 3.6 1.3e-07 31.1 3.6 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_C PF14768.6 EGF77798.1 - 0.0011 19.5 2.4 0.003 18.1 2.4 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal TackOD1 PF18551.1 EGF77798.1 - 0.0024 17.6 1.9 0.0047 16.6 1.9 1.4 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 DUF4905 PF16248.5 EGF77798.1 - 0.042 13.7 0.2 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) ChaC PF04752.12 EGF77799.1 - 3.7e-54 183.5 0.0 4.2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 EGF77799.1 - 0.01 16.4 0.1 0.015 15.9 0.1 1.4 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like DUF4038 PF13204.6 EGF77799.1 - 0.14 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Condensation PF00668.20 EGF77800.1 - 6.4e-10 38.3 0.0 2.2e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Condensation domain APG6_N PF17675.1 EGF77800.1 - 0.069 13.7 2.1 0.21 12.1 2.1 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region GCN5L1 PF06320.13 EGF77800.1 - 1.3 9.2 5.0 59 3.8 0.2 3.9 4 0 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) TMF_TATA_bd PF12325.8 EGF77800.1 - 2.2 8.5 6.8 4.6 7.5 1.8 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4539 PF15072.6 EGF77801.1 - 3.1e-25 88.0 0.0 5.5e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Sec6 PF06046.13 EGF77802.1 - 2.9e-124 415.6 14.6 3.3e-124 415.4 11.1 2.0 2 0 0 2 2 2 2 Exocyst complex component Sec6 Peptidase_M24_C PF16188.5 EGF77802.1 - 0.15 12.2 1.7 1.1 9.4 0.2 3.0 1 1 0 2 2 2 0 C-terminal region of peptidase_M24 HECT PF00632.25 EGF77803.1 - 5.2e-100 334.9 0.0 6.9e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Spc7 PF08317.11 EGF77804.1 - 0.0062 15.5 0.8 0.0062 15.5 0.8 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EGF77804.1 - 1.3 9.1 7.9 3.3 7.8 0.9 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Wbp11 PF09429.10 EGF77804.1 - 9.1 6.8 8.9 18 5.8 0.9 3.0 2 2 2 4 4 4 0 WW domain binding protein 11 Ribonuclease_3 PF00636.26 EGF77805.1 - 6.4e-18 65.3 0.1 1.9e-17 63.8 0.0 1.8 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF77805.1 - 7.3e-11 42.3 0.0 1.2e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like DAG_kinase_N PF14513.6 EGF77811.1 - 0.24 11.6 5.5 0.083 13.1 2.6 1.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus HIT PF01230.23 EGF77812.1 - 5.2e-22 78.4 0.6 6.4e-22 78.1 0.6 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGF77812.1 - 2.1e-05 25.0 0.2 3e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGF77812.1 - 0.0082 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF4464 PF14713.6 EGF77813.1 - 1.1e-94 316.3 4.1 1.2e-94 316.1 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) PTPA PF03095.15 EGF77814.1 - 1.2e-124 415.7 0.5 1.3e-124 415.5 0.5 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Xpo1 PF08389.12 EGF77814.1 - 0.047 13.8 0.2 0.094 12.8 0.2 1.5 1 0 0 1 1 1 0 Exportin 1-like protein Septin PF00735.18 EGF77815.1 - 3.9e-109 364.3 0.0 4.7e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGF77815.1 - 1.3e-08 34.9 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF77815.1 - 2.1e-07 31.0 0.1 6e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGF77815.1 - 1.5e-06 28.4 0.1 0.021 14.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 EGF77815.1 - 0.0012 18.4 0.1 0.0094 15.5 0.0 2.3 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EGF77815.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGF77815.1 - 0.0017 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.16 EGF77815.1 - 0.0027 17.0 0.0 0.0054 16.1 0.0 1.7 1 1 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 EGF77815.1 - 0.0069 16.7 0.0 0.026 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGF77815.1 - 0.0087 16.6 0.3 0.04 14.4 0.2 2.1 2 1 0 2 2 2 1 ABC transporter SRPRB PF09439.10 EGF77815.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EGF77815.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGF77815.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 EGF77815.1 - 0.017 14.9 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EGF77815.1 - 0.032 14.8 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF77815.1 - 0.033 14.6 0.0 0.066 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 EGF77815.1 - 0.044 13.4 0.1 0.09 12.4 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGF77815.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EGF77815.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EGF77815.1 - 0.085 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 NTPase Ras PF00071.22 EGF77815.1 - 0.14 11.7 0.0 0.43 10.2 0.0 1.8 1 1 0 1 1 1 0 Ras family zf-C3HC4 PF00097.25 EGF77816.1 - 1.9e-09 37.2 12.9 3.4e-09 36.4 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF77816.1 - 2.7e-09 36.7 7.9 4.5e-09 36.0 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF77816.1 - 7.1e-07 29.0 11.8 1.3e-06 28.2 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF77816.1 - 2.7e-06 27.6 9.8 4.5e-06 26.9 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 EGF77816.1 - 3.1e-06 27.0 1.7 5.4e-06 26.2 1.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGF77816.1 - 3.2e-06 27.0 11.9 5.5e-06 26.2 11.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGF77816.1 - 4e-06 26.6 8.3 6.8e-06 25.8 8.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF77816.1 - 5.3e-06 26.4 8.4 1e-05 25.4 8.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger MPS2 PF17060.5 EGF77816.1 - 0.0002 20.7 11.2 0.00027 20.3 11.2 1.3 1 0 0 1 1 1 1 Monopolar spindle protein 2 zf-C3HC4_4 PF15227.6 EGF77816.1 - 0.0005 20.2 9.8 0.00097 19.2 9.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGF77816.1 - 0.00079 19.7 5.9 0.0018 18.5 5.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 EGF77816.1 - 0.0018 18.1 3.6 0.0018 18.1 3.6 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGF77816.1 - 0.0032 17.2 8.1 0.0076 16.0 8.1 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Laminin_II PF06009.12 EGF77816.1 - 0.0034 17.4 5.5 0.0034 17.4 5.5 1.8 1 1 1 2 2 2 1 Laminin Domain II PDDEXK_7 PF04411.12 EGF77816.1 - 0.0062 16.5 2.8 0.007 16.4 2.8 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF1272 PF06906.11 EGF77816.1 - 0.032 14.3 6.1 0.094 12.8 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) GyrB_insert PF18053.1 EGF77816.1 - 0.037 13.9 5.0 0.023 14.6 3.5 1.4 1 1 0 1 1 1 0 DNA gyrase B subunit insert domain MMPL PF03176.15 EGF77816.1 - 0.084 11.8 0.3 0.11 11.3 0.3 1.2 1 0 0 1 1 1 0 MMPL family zf-tcix PF14952.6 EGF77816.1 - 0.13 11.9 4.0 0.17 11.5 0.3 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-Nse PF11789.8 EGF77816.1 - 0.14 12.0 3.6 0.29 11.0 3.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IpgD PF05925.12 EGF77816.1 - 0.22 10.0 4.8 0.27 9.8 4.8 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD zf-ribbon_3 PF13248.6 EGF77816.1 - 0.25 10.8 0.1 0.25 10.8 0.1 2.4 3 0 0 3 3 2 0 zinc-ribbon domain YkyA PF10368.9 EGF77816.1 - 0.31 10.7 15.3 0.81 9.3 15.3 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein SHE3 PF17078.5 EGF77816.1 - 0.33 10.6 17.7 1.5 8.5 17.3 1.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Exonuc_VII_L PF02601.15 EGF77816.1 - 1.3 8.5 11.4 1.6 8.2 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_L37e PF01907.19 EGF77816.1 - 1.9 8.7 8.4 0.45 10.7 4.5 1.9 1 1 0 1 1 1 0 Ribosomal protein L37e V_ATPase_I PF01496.19 EGF77816.1 - 2 6.2 9.7 2.3 6.0 9.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DZR PF12773.7 EGF77816.1 - 2.4 8.3 10.3 3.2 7.8 8.6 2.0 2 1 0 2 2 1 0 Double zinc ribbon Mod_r PF07200.13 EGF77816.1 - 3 8.0 19.9 1.8 8.6 9.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Rota_VP2 PF05087.12 EGF77816.1 - 3.6 5.6 8.0 4.1 5.4 8.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Noelin-1 PF12308.8 EGF77816.1 - 4.7 7.3 12.8 3 7.9 4.0 2.6 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF3683 PF12447.8 EGF77816.1 - 6.7 6.9 7.7 25 5.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) DUF4379 PF14311.6 EGF77816.1 - 7.3 7.0 8.1 1.5e+02 2.8 8.0 2.4 1 1 0 1 1 1 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGF77816.1 - 9.5 6.4 10.6 8.9e+02 0.1 10.6 2.7 1 1 0 1 1 1 0 Zinc ribbon domain HemX PF04375.14 EGF77816.1 - 9.7 5.4 16.6 32 3.6 15.3 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase NRDE-2 PF08424.10 EGF77817.1 - 1e-83 281.2 6.3 1e-83 281.2 6.3 2.8 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGF77817.1 - 1.7e-10 40.8 3.6 0.0016 19.1 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF77817.1 - 6.4e-06 25.9 2.4 0.0046 17.0 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGF77817.1 - 5.2e-05 23.2 5.6 0.5 10.3 0.0 4.3 3 1 1 4 4 4 2 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 EGF77817.1 - 8.5e-05 22.7 2.0 3.3 8.3 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF77817.1 - 0.00038 20.9 6.2 0.1 13.1 0.0 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF77817.1 - 0.00063 20.3 4.4 0.018 15.7 1.3 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF77817.1 - 0.0022 18.3 1.4 0.012 15.9 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF77817.1 - 0.017 15.3 2.2 0.57 10.5 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Suf PF05843.14 EGF77817.1 - 0.047 13.7 9.7 0.4 10.6 0.2 4.1 5 0 0 5 5 5 0 Suppressor of forked protein (Suf) DUF212 PF02681.14 EGF77817.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Divergent PAP2 family TPR_11 PF13414.6 EGF77817.1 - 0.15 11.7 0.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 EGF77817.1 - 0.19 11.6 2.1 18 5.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF77817.1 - 0.22 10.9 6.5 0.24 10.7 0.5 3.1 4 0 0 4 4 4 0 MalT-like TPR region PAP2 PF01569.21 EGF77817.1 - 1.4 8.7 3.6 3 7.6 0.0 2.7 3 0 0 3 3 3 0 PAP2 superfamily TPR_6 PF13174.6 EGF77817.1 - 2.8 8.8 4.7 26 5.7 0.1 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat HEPN_MAE_28990 PF18737.1 EGF77817.1 - 3.2 7.6 8.7 8 6.3 0.0 3.3 3 0 0 3 3 3 0 MAE_28990/MAE_18760-like HEPN ANAPC4_WD40 PF12894.7 EGF77818.1 - 2.2e-08 34.3 0.4 1.4e-05 25.3 0.0 3.4 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF77818.1 - 0.00045 21.0 12.5 0.23 12.4 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4148 PF13663.6 EGF77820.1 - 2.2 8.5 6.3 2.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Peptidase_M36 PF02128.15 EGF77821.1 - 2e-136 455.0 0.2 2.3e-136 454.8 0.2 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) DUF3573 PF12097.8 EGF77821.1 - 0.018 13.9 0.2 0.027 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF5132 PF17195.4 EGF77821.1 - 0.19 11.9 0.1 5.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Sigma70_ner PF04546.13 EGF77822.1 - 0.012 15.6 0.7 0.015 15.2 0.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4558 PF15104.6 EGF77822.1 - 1.2 9.3 9.0 0.051 13.6 2.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4558) DUF4246 PF14033.6 EGF77823.1 - 1.7e-86 291.2 0.3 2.1e-86 290.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Rsbr_N PF08678.10 EGF77824.1 - 0.0034 17.4 0.5 0.012 15.7 0.2 2.0 1 1 1 2 2 2 1 Rsbr N terminal PA26 PF04636.13 EGF77824.1 - 0.025 13.5 0.7 0.029 13.3 0.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PI3K_P85_iSH2 PF16454.5 EGF77824.1 - 0.037 13.6 6.8 0.085 12.5 6.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PhoU PF01895.19 EGF77824.1 - 0.26 11.8 2.6 1.6 9.3 1.8 2.5 2 1 0 2 2 2 0 PhoU domain Uteroglobin PF01099.17 EGF77824.1 - 0.92 9.9 3.8 16 5.9 0.0 2.7 3 0 0 3 3 3 0 Uteroglobin family Asp PF00026.23 EGF77825.1 - 1.9e-13 50.6 0.0 9.1e-09 35.2 0.0 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77825.1 - 0.0031 17.3 0.1 1.4 8.7 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF77825.1 - 0.018 15.6 0.2 5.4 7.6 0.1 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sigma70_ner PF04546.13 EGF77826.1 - 0.0079 16.1 0.9 0.01 15.8 0.9 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Cytochrom_B562 PF07361.11 EGF77826.1 - 0.11 13.1 3.1 0.11 13.1 0.4 2.0 2 0 0 2 2 2 0 Cytochrome b562 DUF4558 PF15104.6 EGF77826.1 - 0.62 10.2 5.9 0.16 12.0 1.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4558) TPR_1 PF00515.28 EGF77827.1 - 2e-20 71.7 7.8 0.00027 20.6 0.0 8.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGF77827.1 - 2.3e-18 64.8 13.0 0.0027 17.7 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGF77827.1 - 1.2e-13 50.1 11.2 0.079 13.2 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGF77827.1 - 1.9e-12 46.9 4.3 0.91 10.5 0.0 8.4 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF77827.1 - 1.1e-11 44.8 2.3 0.00091 19.5 0.1 5.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGF77827.1 - 8.7e-09 34.8 2.2 0.061 13.4 0.1 5.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF77827.1 - 9.2e-08 32.5 6.7 0.12 13.0 0.0 6.1 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF77827.1 - 8.8e-07 28.5 0.3 0.1 12.3 0.0 4.5 4 0 0 4 4 3 2 TPR repeat TPR_16 PF13432.6 EGF77827.1 - 2.1e-05 25.1 3.8 4.8 7.9 0.0 5.5 6 1 1 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF77827.1 - 0.0021 18.1 8.4 1.1 9.3 0.0 4.8 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 EGF77827.1 - 0.0026 17.2 2.0 0.99 8.7 0.1 3.3 3 0 0 3 3 3 2 MalT-like TPR region ANAPC3 PF12895.7 EGF77827.1 - 0.0036 17.5 19.3 1.5 9.1 0.0 6.1 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF5113 PF17140.4 EGF77827.1 - 0.0095 15.8 0.3 5.3 6.8 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF5113) NARP1 PF12569.8 EGF77827.1 - 0.016 14.1 0.8 12 4.7 0.0 3.2 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EGF77827.1 - 0.029 13.6 0.0 0.38 9.9 0.0 2.6 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF77827.1 - 0.029 15.0 1.6 1.9e+02 3.0 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 EGF77827.1 - 0.066 13.4 0.3 40 4.5 0.0 4.5 6 0 0 6 6 4 0 PPR repeat family TPR_9 PF13371.6 EGF77827.1 - 0.078 13.1 3.5 7.1 6.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF77827.1 - 0.091 13.2 1.8 4.3 7.9 0.1 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat DOT1 PF08123.13 EGF77828.1 - 6.9e-61 205.4 0.0 1.2e-60 204.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 EGF77828.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGF77828.1 - 0.019 15.6 0.0 0.045 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGF77828.1 - 0.02 15.6 0.0 0.057 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CH PF00307.31 EGF77829.1 - 3.5e-80 265.3 4.7 6.4e-22 77.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGF77829.1 - 2.7e-07 30.3 0.1 0.0015 18.4 0.0 4.1 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 EGF77829.1 - 0.026 14.9 0.0 0.098 13.1 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair CH_2 PF06294.11 EGF77829.1 - 0.059 13.5 0.1 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 CH-like domain in sperm protein SMN PF06003.12 EGF77830.1 - 0.073 12.3 0.4 0.073 12.3 0.4 3.4 1 1 2 3 3 3 0 Survival motor neuron protein (SMN) Ribosomal_L32p PF01783.23 EGF77830.1 - 0.1 12.8 1.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L32p protein family KH_1 PF00013.29 EGF77831.1 - 9.2e-30 102.3 0.1 2.8e-08 33.5 0.0 7.4 7 0 0 7 7 7 5 KH domain SAM_1 PF00536.30 EGF77831.1 - 1.8e-13 50.7 0.0 5.3e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGF77831.1 - 4.6e-09 36.3 0.1 1.2e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DEAD PF00270.29 EGF77832.1 - 4.2e-22 78.8 0.8 1.2e-21 77.3 0.8 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF77832.1 - 6.4e-11 42.6 0.0 2.3e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF77832.1 - 3.9e-06 27.0 0.1 0.0013 18.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ParBc PF02195.18 EGF77832.1 - 0.13 12.6 0.1 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 ParB-like nuclease domain AAA_22 PF13401.6 EGF77832.1 - 0.21 11.8 1.0 2.9 8.2 1.0 2.3 1 1 0 1 1 1 0 AAA domain RRM_2 PF04059.12 EGF77833.1 - 1.4e-38 131.0 0.5 2.8e-38 130.0 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGF77833.1 - 2.9e-11 43.0 0.3 9.4e-06 25.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 EGF77833.1 - 0.031 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Smg-4/UPF3 family zf-U1 PF06220.12 EGF77834.1 - 7.7e-11 41.6 2.8 1.3e-10 40.8 2.8 1.4 1 0 0 1 1 1 1 U1 zinc finger 4HBT PF03061.22 EGF77835.1 - 1.4e-11 44.6 0.1 2.6e-11 43.7 0.1 1.4 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 EGF77835.1 - 0.00037 20.6 0.1 0.00043 20.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EGF77835.1 - 0.041 14.1 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily dCMP_cyt_deam_1 PF00383.23 EGF77836.1 - 1.4e-10 41.0 0.2 5.3e-10 39.1 0.2 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGF77836.1 - 8e-09 35.4 0.1 7.3e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 EGF77836.1 - 0.0039 17.3 0.1 0.0088 16.1 0.1 1.5 1 0 0 1 1 1 1 Bd3614-like deaminase WD40 PF00400.32 EGF77837.1 - 6.8e-09 36.2 3.2 0.28 12.1 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77837.1 - 1.9e-07 31.3 0.0 0.15 12.3 0.0 4.1 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain 2OG-FeII_Oxy_4 PF13661.6 EGF77838.1 - 1e-28 99.8 0.0 9.6e-28 96.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 EGF77838.1 - 9.6e-28 97.2 0.0 4e-22 78.8 0.0 3.9 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.6 EGF77838.1 - 3.4e-16 59.9 0.0 9.6e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGF77838.1 - 0.064 13.8 0.0 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Peptidase_C15 PF01470.17 EGF77839.1 - 6.4e-16 59.1 0.1 8.3e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase PgaPase_1 PF06162.12 EGF77839.1 - 0.0003 20.6 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative pyroglutamyl peptidase PgaPase_1 Med25_VWA PF11265.8 EGF77840.1 - 3.3e-26 92.4 0.2 3.3e-26 92.4 0.2 2.2 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A VWA_2 PF13519.6 EGF77840.1 - 0.0001 22.9 0.0 0.0001 22.9 0.0 5.4 4 1 1 5 5 5 1 von Willebrand factor type A domain MarC PF01914.17 EGF77840.1 - 0.12 11.7 1.2 0.32 10.4 0.1 2.2 2 0 0 2 2 2 0 MarC family integral membrane protein Hint_2 PF13403.6 EGF77840.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.9 3 0 0 3 3 3 0 Hint domain Peptidase_M36 PF02128.15 EGF77841.1 - 1.9e-101 339.9 2.2 2.1e-101 339.8 2.2 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) SRF-TF PF00319.18 EGF77842.1 - 4.9e-23 80.4 0.1 6.6e-23 79.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Trp_oprn_chp PF09534.10 EGF77843.1 - 0.0068 16.2 0.7 0.011 15.6 0.7 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3120 PF11318.8 EGF77843.1 - 0.008 16.5 0.4 0.011 16.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3120) Amnionless PF14828.6 EGF77843.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless SseC PF04888.12 EGF77843.1 - 0.071 12.7 0.7 0.091 12.3 0.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family UPF0239 PF06783.11 EGF77843.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF2613 PF11021.8 EGF77843.1 - 0.55 10.4 5.5 0.62 10.2 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) Pkinase PF00069.25 EGF77844.1 - 2.1e-71 240.4 0.0 2.5e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77844.1 - 8.9e-31 107.1 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF77844.1 - 0.0085 15.1 0.2 0.11 11.5 0.2 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF77844.1 - 0.038 13.9 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGF77844.1 - 0.044 12.8 0.1 0.093 11.8 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Ras PF00071.22 EGF77845.1 - 7e-59 198.1 0.7 8.9e-59 197.7 0.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF77845.1 - 1.4e-36 125.4 0.1 2.2e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF77845.1 - 1.2e-14 54.2 0.1 1.4e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF77845.1 - 3.9e-06 26.5 0.2 2.8e-05 23.7 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGF77845.1 - 6e-06 25.8 0.1 9.3e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGF77845.1 - 5.5e-05 23.2 0.1 9.1e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF77845.1 - 7.3e-05 22.7 0.0 0.071 13.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGF77845.1 - 0.00026 20.4 0.2 0.00032 20.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGF77845.1 - 0.0075 15.8 0.1 0.25 10.9 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_28 PF13521.6 EGF77845.1 - 0.029 14.6 0.0 2 8.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGF77845.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein NIF PF03031.18 EGF77846.1 - 9.1e-52 175.0 0.3 1e-51 174.8 0.3 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Transmemb_17 PF09799.9 EGF77847.1 - 1e-07 32.5 0.4 1.3e-07 32.2 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein NAP PF00956.18 EGF77848.1 - 4.7e-90 301.4 6.9 6.8e-90 300.9 6.9 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) RabGAP-TBC PF00566.18 EGF77849.1 - 3.4e-50 170.7 0.1 5.3e-50 170.0 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 EGF77850.1 - 1.9e-34 117.3 0.0 2.4e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF77850.1 - 0.016 15.3 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 EGF77850.1 - 0.04 13.5 0.0 0.94 9.1 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGF77850.1 - 0.058 13.6 0.1 2.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 EGF77850.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif OB_RNB PF08206.11 EGF77850.1 - 0.18 11.5 0.2 9.8 5.9 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain LRR_6 PF13516.6 EGF77852.1 - 2.4e-16 58.3 20.7 1.6e-05 24.5 0.1 6.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 EGF77852.1 - 0.0011 19.4 16.5 0.081 13.4 0.4 5.2 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF77852.1 - 0.0061 16.9 7.9 20 6.2 0.0 5.9 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EGF77852.1 - 0.011 15.4 13.4 1.2 9.0 2.0 4.9 3 1 2 5 5 5 0 Leucine rich repeat PPR PF01535.20 EGF77853.1 - 2.3e-06 27.5 0.7 0.0026 17.9 0.0 3.8 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 EGF77853.1 - 1.3e-05 25.3 0.1 0.0003 20.9 0.0 2.7 2 0 0 2 2 2 1 PPR repeat family PPR_1 PF12854.7 EGF77853.1 - 0.0049 16.6 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 EGF77853.1 - 0.021 14.9 0.1 43 4.3 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_19 PF14559.6 EGF77854.1 - 1.1e-05 25.9 2.0 0.017 15.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF77854.1 - 0.034 13.5 0.7 0.4 10.0 0.0 2.3 2 0 0 2 2 2 0 MalT-like TPR region DUF2795 PF11387.8 EGF77854.1 - 0.069 13.4 0.1 0.38 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) PPR_long PF17177.4 EGF77854.1 - 0.1 11.9 0.5 0.42 10.0 0.3 2.1 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP zf-C2H2 PF00096.26 EGF77856.1 - 2.2e-12 46.7 21.8 4.4e-05 23.7 0.6 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF77856.1 - 3.1e-11 43.2 15.4 6.7e-05 23.1 0.5 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF77856.1 - 4.9e-10 39.4 21.7 0.00088 19.9 0.8 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF77856.1 - 0.00016 21.9 16.0 0.025 14.9 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.7 EGF77856.1 - 0.018 15.0 5.2 0.077 13.0 0.6 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 EGF77856.1 - 0.029 14.1 13.9 1.5 8.6 0.0 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EGF77856.1 - 0.037 14.1 18.8 0.077 13.0 0.5 4.1 5 0 0 5 5 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 EGF77856.1 - 0.064 13.2 4.3 2.7 8.0 0.0 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Actin_micro PF17003.5 EGF77856.1 - 0.14 11.3 3.4 0.044 13.0 0.4 1.7 1 1 1 2 2 2 0 Putative actin-like family zf-C2HE PF16278.5 EGF77856.1 - 0.15 12.6 5.6 2.8 8.4 0.1 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger OmpH PF03938.14 EGF77856.1 - 0.17 12.2 7.3 0.41 11.0 7.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HypA PF01155.19 EGF77856.1 - 0.21 11.6 2.8 2.4 8.2 2.8 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 EGF77856.1 - 0.27 11.2 3.3 1.5 8.9 1.6 2.8 3 0 0 3 3 2 0 Adenylate kinase, active site lid zf_UBZ PF18439.1 EGF77856.1 - 0.29 10.8 8.8 2.2 7.9 0.2 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 EGF77856.1 - 0.36 11.1 2.5 18 5.7 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon DUF2225 PF09986.9 EGF77856.1 - 0.38 10.4 4.0 0.33 10.6 1.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FYVE PF01363.21 EGF77856.1 - 0.55 10.4 4.7 3.5 7.8 4.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-AN1 PF01428.16 EGF77856.1 - 0.57 10.4 8.9 14 5.9 0.2 3.5 3 0 0 3 3 3 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 EGF77856.1 - 1.4 8.7 23.8 0.34 10.7 1.7 4.3 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 EGF77856.1 - 1.6 8.9 7.7 0.7 10.1 2.0 2.9 1 1 2 3 3 3 0 Zinc ribbon domain DZR PF12773.7 EGF77856.1 - 5 7.2 5.8 23 5.1 5.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 EGF77856.1 - 8.7 6.4 7.0 27 4.8 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon SF3b1 PF08920.10 EGF77857.1 - 3.2e-43 147.0 14.3 9.9e-43 145.4 3.2 3.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EGF77857.1 - 4.9e-14 52.5 0.1 0.38 11.3 0.0 8.2 9 1 1 10 10 10 3 HEAT-like repeat HEAT PF02985.22 EGF77857.1 - 1.2e-11 43.9 2.5 4.6 7.8 0.1 9.4 11 0 0 11 11 10 2 HEAT repeat HEAT_2 PF13646.6 EGF77857.1 - 1.2e-09 38.4 2.7 0.17 12.3 0.0 7.7 5 2 2 7 7 7 2 HEAT repeats DUF3385 PF11865.8 EGF77857.1 - 3.4e-06 27.1 0.8 0.061 13.2 0.1 5.1 4 1 0 5 5 5 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EGF77857.1 - 3.9e-05 23.8 4.7 2 8.5 0.0 5.5 6 2 1 7 7 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGF77857.1 - 0.0002 21.9 0.3 15 6.3 0.0 5.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 EGF77857.1 - 0.00038 19.7 0.1 0.77 8.8 0.0 4.2 2 1 1 4 4 4 1 Dopey, N-terminal MMS19_C PF12460.8 EGF77857.1 - 0.0023 17.1 0.0 0.16 11.0 0.0 3.2 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal NUC173 PF08161.12 EGF77857.1 - 0.0047 16.6 1.2 7 6.3 0.0 4.9 3 2 2 5 5 5 1 NUC173 domain Arm PF00514.23 EGF77857.1 - 0.0052 16.8 0.1 40 4.4 0.0 5.0 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 EGF77857.1 - 0.0076 16.0 0.0 2.8 7.7 0.0 3.3 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 EGF77857.1 - 0.017 13.7 0.7 0.35 9.4 0.0 2.7 2 1 0 2 2 2 0 Adaptin N terminal region CLASP_N PF12348.8 EGF77857.1 - 0.027 14.1 1.1 10 5.6 0.0 3.3 4 0 0 4 4 4 0 CLASP N terminal MMS22L_C PF14911.6 EGF77857.1 - 0.074 12.1 0.0 0.27 10.3 0.0 1.9 1 1 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal DRIM PF07539.12 EGF77857.1 - 0.13 10.5 0.1 13 3.9 0.0 3.3 2 1 2 4 4 4 0 Down-regulated in metastasis Yae1_N PF09811.9 EGF77858.1 - 9.3e-05 22.0 9.6 9.3e-05 22.0 9.6 1.6 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SARAF PF06682.12 EGF77858.1 - 0.36 10.4 5.2 0.054 13.1 0.9 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1482 PF07358.11 EGF77859.1 - 0.13 12.1 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) ArfGap PF01412.18 EGF77860.1 - 1.8e-20 73.2 2.7 1.8e-20 73.2 2.7 5.4 3 3 1 4 4 4 1 Putative GTPase activating protein for Arf UBA PF00627.31 EGF77860.1 - 5.3e-06 26.2 0.4 1.2e-05 25.1 0.4 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RNase_T PF00929.24 EGF77861.1 - 7.6e-18 65.6 0.0 1.6e-17 64.5 0.0 1.5 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGF77861.1 - 2.2e-06 27.5 0.0 5.4e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease CW_7 PF08230.11 EGF77861.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 CW_7 repeat Sybindin PF04099.12 EGF77862.1 - 1.7e-30 105.8 0.0 2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGF77862.1 - 0.034 14.3 0.1 0.04 14.0 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region WD40 PF00400.32 EGF77863.1 - 3.9e-24 84.5 15.3 1.7e-06 28.6 0.0 9.2 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77863.1 - 2.3e-12 47.0 0.4 5.1e-06 26.7 0.0 5.9 6 2 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 EGF77863.1 - 8e-09 35.2 1.0 1.7e-08 34.2 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EGF77863.1 - 4.4e-06 27.0 0.5 8.9e-06 26.1 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair Ge1_WD40 PF16529.5 EGF77863.1 - 0.00058 18.9 0.0 0.66 8.9 0.0 3.3 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF77863.1 - 0.0011 17.7 0.4 0.19 10.3 0.0 3.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 EF-hand_6 PF13405.6 EGF77863.1 - 0.0042 16.9 0.3 6.5 7.0 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGF77863.1 - 0.022 14.3 1.7 1 9.1 0.5 2.8 2 0 0 2 2 2 0 EF hand p25-alpha PF05517.12 EGF77863.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 p25-alpha DUF3993 PF13158.6 EGF77863.1 - 0.077 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Pex19 PF04614.12 EGF77864.1 - 8.3e-50 169.8 13.7 1e-49 169.5 13.7 1.1 1 0 0 1 1 1 1 Pex19 protein family DUF5344 PF17279.2 EGF77864.1 - 0.22 12.1 2.9 5.5 7.6 0.1 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5344) Exo5 PF09810.9 EGF77864.1 - 0.86 9.0 6.9 4.5 6.6 6.9 2.0 1 1 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease NAD_kinase PF01513.21 EGF77865.1 - 7.1e-60 202.7 0.0 1e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF4363 PF14276.6 EGF77865.1 - 0.096 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DAGK_cat PF00781.24 EGF77865.1 - 0.15 11.6 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Nop PF01798.18 EGF77866.1 - 4.8e-83 278.1 0.2 1e-82 277.1 0.2 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGF77866.1 - 1e-21 77.1 0.7 3.8e-21 75.2 0.7 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain EppA_BapA PF07268.11 EGF77866.1 - 0.084 12.8 3.0 13 5.8 0.1 3.5 4 0 0 4 4 4 0 Exported protein precursor (EppA/BapA) VIR_N PF15912.5 EGF77866.1 - 0.32 10.5 10.5 0.48 10.0 10.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal AP3D1 PF06375.11 EGF77866.1 - 0.46 10.7 14.7 0.89 9.8 14.7 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 RR_TM4-6 PF06459.12 EGF77866.1 - 1.4 8.7 10.0 2.4 7.9 10.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lyase_1 PF00206.20 EGF77867.1 - 1e-115 386.4 0.0 1.4e-115 386.0 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGF77867.1 - 4e-25 88.0 0.0 4e-25 88.0 0.0 2.4 3 0 0 3 3 3 1 Fumarase C C-terminus Baculo_PEP_C PF04513.12 EGF77868.1 - 0.079 13.0 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BDM PF10684.9 EGF77868.1 - 0.088 13.2 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein DUF2408 PF10303.9 EGF77868.1 - 0.11 13.0 0.1 0.16 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) LapA_dom PF06305.11 EGF77870.1 - 0.55 10.1 3.4 5.9 6.8 1.3 3.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Sec7_N PF12783.7 EGF77871.1 - 0.093 12.6 2.9 5.7 6.8 0.4 2.8 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PALP PF00291.25 EGF77872.1 - 5.4e-60 203.3 0.0 6.7e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF570 PF04489.13 EGF77872.1 - 0.046 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) zf-ZPR1 PF03367.13 EGF77873.1 - 2.6e-108 358.9 3.0 1.1e-55 187.9 0.1 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DZR PF12773.7 EGF77873.1 - 5.9 7.0 10.4 24 5.0 4.1 3.1 2 2 0 2 2 2 0 Double zinc ribbon 2-Hacid_dh_C PF02826.19 EGF77874.1 - 1e-52 178.0 0.0 1.7e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGF77874.1 - 3.9e-28 97.8 0.1 5.5e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGF77874.1 - 6.9e-05 23.1 0.1 0.00042 20.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGF77874.1 - 0.0038 17.3 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase OPA3 PF07047.12 EGF77875.1 - 7.6e-40 135.6 0.8 8.4e-40 135.4 0.0 1.4 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) EzrA PF06160.12 EGF77875.1 - 0.0059 14.8 0.4 0.0075 14.5 0.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA ATG16 PF08614.11 EGF77875.1 - 0.01 16.1 1.5 0.014 15.6 1.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 EGF77875.1 - 0.016 15.8 0.6 0.025 15.2 0.6 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 EGF77875.1 - 0.022 15.3 0.9 0.027 15.0 0.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region PhaP_Bmeg PF09602.10 EGF77875.1 - 0.041 13.8 0.6 0.058 13.3 0.6 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) RILP PF11461.8 EGF77875.1 - 0.05 13.8 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein Adeno_52K PF03052.15 EGF77875.1 - 0.057 12.8 1.2 0.19 11.1 0.4 2.0 1 1 1 2 2 2 0 Adenoviral protein L1 52/55-kDa DUF848 PF05852.11 EGF77875.1 - 0.06 13.5 0.3 0.099 12.8 0.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.12 EGF77875.1 - 0.074 13.7 1.0 0.15 12.7 1.0 1.6 1 1 0 1 1 1 0 SlyX DUF1192 PF06698.11 EGF77875.1 - 0.08 13.0 0.8 0.17 12.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Ribosomal_L29 PF00831.23 EGF77875.1 - 0.087 12.8 0.5 0.19 11.7 0.5 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein T2SSE_N PF05157.15 EGF77875.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain YabA PF06156.13 EGF77875.1 - 0.15 12.7 0.6 0.22 12.1 0.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA TSC22 PF01166.18 EGF77875.1 - 0.2 12.0 1.8 0.46 10.8 0.9 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family PDEase_I PF00233.19 EGF77876.1 - 5.8e-81 271.7 4.0 6.7e-81 271.5 4.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CofC PF01983.16 EGF77876.1 - 0.0017 17.6 0.1 0.0034 16.6 0.1 1.4 1 0 0 1 1 1 1 Guanylyl transferase CofC like Fer2 PF00111.27 EGF77878.1 - 2.2e-15 56.4 0.3 2.7e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LpxI_C PF06230.11 EGF77879.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 LpxI C-terminal domain HA2 PF04408.23 EGF77880.1 - 2.9e-23 82.2 2.8 8.1e-23 80.8 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGF77880.1 - 1.5e-14 54.3 0.0 3.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGF77880.1 - 1.3e-12 47.9 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGF77880.1 - 5.8e-06 26.2 0.1 2.1e-05 24.4 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EGF77880.1 - 2.5e-05 23.7 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGF77880.1 - 4.7e-05 23.7 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF77880.1 - 0.00055 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGF77880.1 - 0.00065 18.8 0.0 0.0023 17.0 0.0 1.8 1 1 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGF77880.1 - 0.0026 18.1 0.1 0.0058 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGF77880.1 - 0.007 16.4 0.0 3.4 7.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 EGF77880.1 - 0.0082 15.8 0.4 0.041 13.5 0.4 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EGF77880.1 - 0.01 15.9 0.0 0.069 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EGF77880.1 - 0.023 14.1 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 EGF77880.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.6 EGF77880.1 - 0.039 14.4 0.3 0.039 14.4 0.3 2.9 2 1 1 4 4 4 0 AAA domain AAA_16 PF13191.6 EGF77880.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 EGF77881.1 - 9.6e-43 146.0 0.2 1.4e-42 145.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF77881.1 - 3.8e-24 85.2 4.0 1.4e-23 83.3 0.6 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EGF77881.1 - 0.035 13.4 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit GFA PF04828.14 EGF77882.1 - 0.0033 17.7 0.2 0.4 11.1 0.1 2.1 1 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Tox-SGS PF15651.6 EGF77882.1 - 0.023 14.9 0.0 0.077 13.2 0.0 1.7 1 1 1 2 2 2 0 Salivary glad secreted protein domain toxin zf-ribbon_3 PF13248.6 EGF77882.1 - 0.024 14.0 0.7 3.4 7.2 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 EGF77882.1 - 0.038 13.9 0.9 4.6 7.2 0.2 2.5 2 0 0 2 2 2 0 Nudix N-terminal Desulfoferrod_N PF06397.12 EGF77882.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain WD40 PF00400.32 EGF77883.1 - 5.2e-56 185.3 13.6 3.8e-07 30.7 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77883.1 - 1e-16 61.0 0.5 0.0018 18.5 0.0 6.3 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF77883.1 - 3.3e-05 23.0 2.8 3.9 6.3 0.0 5.0 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGF77883.1 - 9.3e-05 21.9 2.5 1 8.6 0.3 4.3 2 2 1 4 4 4 1 WD40-like domain Nup160 PF11715.8 EGF77883.1 - 0.00077 18.2 0.6 4.3 5.9 0.0 4.1 1 1 1 4 4 4 1 Nucleoporin Nup120/160 CEP19 PF14933.6 EGF77883.1 - 0.0018 18.6 0.1 0.0027 18.0 0.1 1.3 1 0 0 1 1 1 1 CEP19-like protein TnpW PF14202.6 EGF77883.1 - 0.26 11.2 0.5 6.6 6.6 0.0 2.9 3 0 0 3 3 3 0 Transposon-encoded protein TnpW RHSP PF07999.11 EGF77884.1 - 0.071 11.9 0.4 6.4 5.5 0.0 2.5 3 0 0 3 3 3 0 Retrotransposon hot spot protein AAA_22 PF13401.6 EGF77884.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGF77884.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Iwr1 PF08574.10 EGF77885.1 - 4.6e-12 46.8 11.3 4.6e-12 46.8 11.3 2.9 3 0 0 3 3 3 1 Transcription factor Iwr1 GP24_25 PF17388.2 EGF77885.1 - 1.3 9.0 4.3 20 5.2 1.2 2.7 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 CLASP_N PF12348.8 EGF77886.1 - 1.7e-13 50.7 17.5 1.1e-07 31.7 1.6 4.3 3 1 1 4 4 4 2 CLASP N terminal HEAT_2 PF13646.6 EGF77886.1 - 1.2e-07 32.0 0.3 0.34 11.3 0.0 5.7 3 2 2 5 5 5 2 HEAT repeats UME PF08064.13 EGF77886.1 - 0.0045 16.9 6.9 0.4 10.6 0.0 4.4 3 1 1 4 4 4 2 UME (NUC010) domain HEAT PF02985.22 EGF77886.1 - 0.066 13.5 19.7 3.2 8.3 0.0 8.3 9 0 0 9 9 9 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EGF77886.1 - 0.16 12.5 1.9 63 4.3 0.3 4.6 2 2 3 5 5 5 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EGF77886.1 - 0.2 11.8 1.8 0.95 9.5 0.1 3.0 2 1 0 2 2 2 0 Parkin co-regulated protein DUF5578 PF17741.1 EGF77886.1 - 0.84 9.0 8.3 0.5 9.8 0.1 3.5 3 2 1 4 4 4 0 Family of unknown function (DUF5578) Pkinase PF00069.25 EGF77887.1 - 1.8e-53 181.6 0.1 4.5e-53 180.3 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77887.1 - 2e-22 79.7 0.0 2.9e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF77887.1 - 0.0008 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF77887.1 - 0.0091 15.6 0.4 0.023 14.3 0.4 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF77887.1 - 0.027 14.0 0.4 0.071 12.7 0.3 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EGF77887.1 - 0.084 12.2 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H_2 PF13832.6 EGF77888.1 - 9.1e-30 103.1 6.0 9.1e-30 103.1 6.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGF77888.1 - 3.9e-24 84.7 3.9 3.9e-24 84.7 3.9 3.0 3 0 0 3 3 2 1 PHD-like zinc-binding domain EPL1 PF10513.9 EGF77888.1 - 1.4e-23 84.0 6.5 1.4e-23 84.0 6.5 3.3 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.6 EGF77888.1 - 2.4e-16 59.0 6.3 1e-14 53.7 2.2 2.9 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.25 EGF77888.1 - 6e-14 51.9 0.3 1.5e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 EGF77888.1 - 1.6e-11 43.9 16.5 1.2e-10 41.1 5.2 3.4 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EGF77888.1 - 0.0006 19.5 1.0 0.0017 18.0 1.0 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EGF77888.1 - 0.0095 15.8 0.3 0.0095 15.8 0.3 3.0 3 0 0 3 3 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EGF77888.1 - 0.49 10.4 12.2 0.13 12.2 3.5 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 EGF77888.1 - 0.62 10.4 13.4 0.46 10.8 1.4 2.8 2 0 0 2 2 2 0 RING-like domain C1_2 PF03107.16 EGF77888.1 - 2.4 8.5 11.5 2 8.8 2.4 2.9 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 EGF77888.1 - 4.9 7.6 16.2 2.3 8.7 1.4 3.2 2 1 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 EGF77888.1 - 6.2 7.1 11.0 1.4 9.1 1.5 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain Methyltr_RsmB-F PF01189.17 EGF77889.1 - 5.1e-30 104.6 0.1 4.6e-28 98.2 0.0 2.5 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F LRR_8 PF13855.6 EGF77890.1 - 2.1e-15 56.2 6.7 3.6e-08 33.0 1.0 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGF77890.1 - 2.5e-11 43.6 11.6 0.0005 20.4 0.2 3.2 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF77890.1 - 0.00018 21.6 5.5 0.39 11.4 0.1 3.8 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 EGF77890.1 - 0.0032 17.4 7.4 1.8 8.8 0.1 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_9 PF14580.6 EGF77890.1 - 0.033 13.7 3.2 0.099 12.1 3.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_3 PF07725.12 EGF77890.1 - 1.1 9.2 5.0 1 9.3 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat UPF0047 PF01894.17 EGF77891.1 - 2.2e-32 111.6 0.1 1.2e-31 109.2 0.1 1.8 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF2045 PF09741.9 EGF77893.1 - 2.2e-37 128.7 0.2 9.2e-22 77.6 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2045) ATE_C PF04377.15 EGF77894.1 - 3e-50 170.3 0.7 4.7e-50 169.7 0.7 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGF77894.1 - 4.8e-25 87.8 0.6 1.1e-24 86.6 0.6 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF374 PF04028.13 EGF77894.1 - 0.047 13.3 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Pkinase PF00069.25 EGF77895.1 - 4e-52 177.2 0.0 6.1e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77895.1 - 4.6e-28 98.2 0.0 6.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF77895.1 - 6.9e-05 22.3 0.0 0.00022 20.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF77895.1 - 0.0079 15.6 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF77895.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase CBM_14 PF01607.24 EGF77895.1 - 4.8 7.4 5.9 1.2 9.3 1.3 2.3 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Serinc PF03348.15 EGF77896.1 - 2.5e-80 270.5 32.0 2e-78 264.2 32.0 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) Holin_SPP1 PF04688.13 EGF77896.1 - 0.27 11.4 3.5 12 6.1 1.0 3.2 2 0 0 2 2 2 0 SPP1 phage holin DUF3043 PF11241.8 EGF77896.1 - 1.1 9.3 3.3 1.2 9.2 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Ribosomal_L23 PF00276.20 EGF77897.1 - 1.5e-15 57.3 0.2 3.2e-15 56.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L23 UTP15_C PF09384.10 EGF77898.1 - 2.5e-46 157.0 0.1 4e-46 156.4 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGF77898.1 - 3.5e-22 78.3 15.5 4.3e-05 24.2 0.6 6.9 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77898.1 - 4.4e-08 33.3 0.4 0.00071 19.8 0.0 3.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EGF77898.1 - 0.051 11.6 0.1 0.34 8.9 0.0 1.9 1 1 1 2 2 2 0 IKI3 family EB1 PF03271.17 EGF77899.1 - 6e-13 48.8 0.9 1.2e-12 47.9 0.9 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EGF77899.1 - 0.00034 20.8 0.5 0.0006 20.0 0.2 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain Pox_A12 PF04651.13 EGF77899.1 - 0.077 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein Croc_4 PF17691.1 EGF77899.1 - 0.58 10.2 5.4 0.97 9.5 5.4 1.3 1 0 0 1 1 1 0 Contingent replication of cDNA 4 DUF2034 PF10356.9 EGF77900.1 - 1.8e-22 79.7 0.1 1.3e-10 41.0 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EGF77900.1 - 1.8e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Isochorismatase PF00857.20 EGF77903.1 - 7.6e-30 104.4 1.3 1.1e-29 103.8 1.3 1.3 1 0 0 1 1 1 1 Isochorismatase family TNV_CP PF03898.13 EGF77903.1 - 0.024 13.9 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein Glyco_transf_4 PF13439.6 EGF77903.1 - 0.12 12.4 0.0 3.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Lum_binding PF00677.17 EGF77904.1 - 3.4e-44 148.7 3.3 2.3e-21 75.6 2.4 2.2 2 0 0 2 2 2 2 Lumazine binding domain DUF211 PF02680.14 EGF77904.1 - 0.053 13.7 2.3 4.1 7.6 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized ArCR, COG1888 Gifsy-2 PF13856.6 EGF77904.1 - 0.13 12.6 0.4 0.33 11.3 0.1 1.8 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage Methyltr_RsmB-F PF01189.17 EGF77905.1 - 3.7e-76 255.2 0.0 5.6e-76 254.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGF77905.1 - 9.6e-07 29.2 0.0 3.4e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 EGF77905.1 - 0.003 18.2 0.0 0.0076 16.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGF77905.1 - 0.003 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 EGF77905.1 - 0.041 13.5 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 EGF77905.1 - 0.05 13.4 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGF77905.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CDC45 PF02724.14 EGF77905.1 - 7.7 4.7 10.1 11 4.2 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Coprogen_oxidas PF01218.18 EGF77906.1 - 2.6e-131 436.7 0.0 2.9e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF1651 PF07864.11 EGF77906.1 - 0.14 12.5 0.0 0.76 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) T6SS_VasE PF05936.12 EGF77906.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE WD40 PF00400.32 EGF77907.1 - 1.3e-20 73.3 16.9 0.0049 17.7 0.1 10.0 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77907.1 - 3.5e-06 27.2 0.0 0.16 12.3 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGF77907.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain Pellino PF04710.14 EGF77909.1 - 2.1e-10 39.9 4.4 4.9e-10 38.7 0.9 2.0 2 0 0 2 2 2 2 Pellino Prok-RING_4 PF14447.6 EGF77909.1 - 0.026 14.4 11.3 0.86 9.5 2.6 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGF77909.1 - 0.27 11.1 9.9 13 5.7 0.0 3.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DFRP_C PF16543.5 EGF77910.1 - 1.8e-24 86.1 4.4 1.8e-24 86.1 4.4 4.1 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EGF77910.1 - 2.2e-07 30.6 11.0 5.6e-07 29.3 1.1 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGF77910.1 - 3.5e-07 29.9 9.0 0.00014 21.5 1.0 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGF77910.1 - 5.9e-07 29.3 19.5 3.6e-05 23.7 6.4 3.0 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 EGF77910.1 - 1.2e-05 25.9 17.6 0.00036 21.2 4.7 3.7 1 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 EGF77910.1 - 0.00058 20.2 7.3 0.12 12.9 1.7 2.5 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGF77910.1 - 0.0069 16.6 0.9 0.66 10.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger containing family NAD_binding_1 PF00175.21 EGF77911.1 - 2.3e-10 41.1 0.0 3.2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGF77911.1 - 0.0013 18.8 0.1 0.007 16.5 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Cas_Cas02710 PF09670.10 EGF77913.1 - 0.00015 20.7 1.0 0.00024 20.1 1.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas02710) DUF4246 PF14033.6 EGF77915.1 - 2.1e-31 109.5 0.0 2.6e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Flavodoxin_5 PF12724.7 EGF77916.1 - 0.044 14.0 0.2 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain TMPIT PF07851.13 EGF77916.1 - 0.17 11.1 2.2 0.28 10.4 2.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 EGF77916.1 - 3.7 6.3 7.0 4.7 5.9 7.0 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter FXR_C1 PF16096.5 EGF77919.1 - 0.22 11.8 7.0 5.3 7.3 2.7 3.0 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 DUF2642 PF10842.8 EGF77922.1 - 0.046 13.6 1.1 19 5.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2642) Arm_vescicular PF18770.1 EGF77923.1 - 0.45 10.5 3.9 0.72 9.8 0.8 2.3 1 1 1 2 2 2 0 Armadillo tether-repeat of vescicular transport factor HNH_2 PF13391.6 EGF77924.1 - 0.22 11.7 2.6 0.72 10.0 0.3 2.5 2 1 0 2 2 2 0 HNH endonuclease ABC_tran PF00005.27 EGF77925.1 - 5.9e-29 101.3 0.0 1.2e-28 100.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGF77925.1 - 5.5e-11 42.8 0.5 8.1e-07 29.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF77925.1 - 0.00023 21.7 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF77925.1 - 0.0012 18.8 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF77925.1 - 0.0014 18.3 0.1 0.0027 17.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGF77925.1 - 0.01 15.3 0.1 0.47 9.9 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF77925.1 - 0.018 15.4 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EGF77925.1 - 0.02 14.6 0.8 0.052 13.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain DLIC PF05783.11 EGF77925.1 - 0.03 13.2 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 EGF77925.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EGF77925.1 - 0.1 12.9 0.0 0.73 10.1 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2620 PF10941.8 EGF77925.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2620 RRM_Rrp7 PF17799.1 EGF77926.1 - 0.0076 16.1 0.7 0.11 12.3 0.1 2.4 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain DCX PF03607.17 EGF77926.1 - 0.072 13.2 0.2 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Doublecortin DED PF01335.21 EGF77926.1 - 0.085 13.2 2.5 0.12 12.7 0.3 2.4 3 1 0 3 3 3 0 Death effector domain Asp PF00026.23 EGF77927.1 - 7e-08 32.3 0.2 2.1e-05 24.1 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77927.1 - 0.007 16.2 0.0 1.5 8.6 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal RecG_N PF17190.4 EGF77928.1 - 0.085 13.6 0.3 0.22 12.2 0.3 1.7 1 0 0 1 1 1 0 RecG N-terminal helical domain WDCP PF15390.6 EGF77928.1 - 7.1 4.9 7.2 13 4.0 7.2 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MciZ PF13072.6 EGF77928.1 - 9.1 6.2 9.3 9.2 6.2 2.2 2.6 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ IstB_IS21 PF01695.17 EGF77929.1 - 0.052 13.3 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein LANC_like PF05147.13 EGF77930.1 - 0.083 11.5 0.5 0.11 11.1 0.5 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein NOC3p PF07540.11 EGF77930.1 - 0.086 13.3 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein Sec2p PF06428.11 EGF77930.1 - 0.13 12.2 2.0 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TBCA PF02970.16 EGF77930.1 - 0.3 11.4 3.4 6.4 7.2 0.2 2.5 1 1 1 2 2 2 0 Tubulin binding cofactor A Fib_alpha PF08702.10 EGF77930.1 - 0.74 10.0 5.2 1.1 9.4 0.3 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Asp PF00026.23 EGF77931.1 - 1.7e-13 50.7 0.1 7.8e-11 41.9 0.0 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77931.1 - 0.055 13.2 0.0 4.3 7.1 0.0 2.3 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal AAA_29 PF13555.6 EGF77932.1 - 0.065 13.0 0.2 11 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGF77932.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain CAP59_mtransfer PF11735.8 EGF77933.1 - 0.1 12.3 0.9 1 9.0 0.1 2.1 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 Tom22 PF04281.13 EGF77933.1 - 1.5 8.6 5.3 0.26 11.0 1.3 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 GPS2_interact PF15784.5 EGF77935.1 - 0.024 15.1 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain WXG100 PF06013.12 EGF77935.1 - 0.11 12.7 3.0 4.1 7.7 0.4 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DASH_Dad2 PF08654.10 EGF77935.1 - 0.55 10.7 4.8 0.34 11.4 0.2 2.7 3 1 0 3 3 3 0 DASH complex subunit Dad2 DUF1275 PF06912.11 EGF77936.1 - 5.8e-10 39.4 1.5 7.3e-10 39.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1275 PF06912.11 EGF77937.1 - 6.4e-10 39.3 1.5 7.4e-10 39.1 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3792 PF12670.7 EGF77937.1 - 0.0054 16.9 1.1 0.0062 16.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) AAA_14 PF13173.6 EGF77941.1 - 0.00023 21.2 0.0 0.98 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Pkinase PF00069.25 EGF77942.1 - 2.4e-14 53.4 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77942.1 - 7.2e-09 35.3 0.0 1.8e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF77942.1 - 6.4e-06 25.7 0.1 8.9e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF77942.1 - 2.8e-05 24.2 0.0 0.001 19.0 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF77942.1 - 0.001 18.4 0.0 0.0024 17.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EGF77942.1 - 0.0043 16.7 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF77942.1 - 0.01 15.4 0.1 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EGF77942.1 - 0.016 14.8 0.1 0.25 10.8 0.0 2.2 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Fructosamin_kin PF03881.14 EGF77942.1 - 0.097 11.9 0.0 0.31 10.2 0.0 1.7 1 1 1 2 2 2 0 Fructosamine kinase PilI PF10623.9 EGF77942.1 - 0.17 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI HNH_2 PF13391.6 EGF77944.1 - 3.5e-06 27.0 0.6 0.00099 19.2 0.0 3.4 3 0 0 3 3 3 1 HNH endonuclease DUF1829 PF08862.10 EGF77944.1 - 0.16 12.5 1.4 2 8.9 1.4 2.6 1 1 0 1 1 1 0 Domain of unknown function DUF1829 AAA_22 PF13401.6 EGF77945.1 - 0.0099 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGF77946.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RecG_N PF17190.4 EGF77947.1 - 0.056 14.2 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 RecG N-terminal helical domain AcylCoA_DH_N PF12418.8 EGF77947.1 - 0.14 12.2 0.2 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase N terminal Asp PF00026.23 EGF77948.1 - 1.9e-14 53.8 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF77948.1 - 2e-05 24.4 0.0 0.00016 21.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal G-patch PF01585.23 EGF77950.1 - 1.9e-16 59.7 0.4 4.1e-16 58.6 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF77950.1 - 1.2e-09 38.1 0.3 5.1e-09 36.1 0.1 2.1 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 EGF77950.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 R3H domain CAS_C PF12026.8 EGF77950.1 - 0.88 9.6 6.6 0.15 12.1 2.3 1.8 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain RRM_1 PF00076.22 EGF77951.1 - 5.2e-24 83.9 0.0 6.1e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF77951.1 - 0.00013 22.0 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EGF77951.1 - 0.0057 16.7 0.1 0.0082 16.2 0.1 1.3 1 1 0 1 1 1 1 Limkain b1 Nup35_RRM PF05172.13 EGF77951.1 - 0.034 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CEP76-C2 PF15627.6 EGF77952.1 - 4.8e-24 84.7 0.0 7.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Arv1 PF04161.13 EGF77953.1 - 1e-58 199.0 2.6 1.3e-58 198.7 2.6 1.1 1 0 0 1 1 1 1 Arv1-like family XRN_N PF03159.18 EGF77954.1 - 7.9e-28 97.5 0.0 9.5e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Pkinase PF00069.25 EGF77955.1 - 2.3e-38 132.1 0.0 2.7e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77955.1 - 2.1e-24 86.2 0.0 2.6e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF77955.1 - 0.00041 19.8 0.0 0.00058 19.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGF77955.1 - 0.00047 19.6 0.0 0.00082 18.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGF77955.1 - 0.00094 19.2 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGF77955.1 - 0.23 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL YCII PF03795.14 EGF77957.1 - 6.4e-08 32.9 0.0 8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Pre-PUA PF17832.1 EGF77958.1 - 1.4e-14 54.5 0.0 4.9e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 EGF77958.1 - 9.5e-14 51.7 0.0 2.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.20 EGF77958.1 - 0.0026 17.7 0.0 0.008 16.1 0.0 1.8 2 0 0 2 2 2 1 PUA domain Kin17_mid PF10357.9 EGF77958.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 EGF77958.1 - 0.0074 16.1 0.1 0.025 14.5 0.1 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain Imm6 PF14434.6 EGF77958.1 - 0.0088 16.0 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 Immunity protein Imm6 Dus PF01207.17 EGF77959.1 - 3.4e-79 266.2 0.0 4.2e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 EGF77959.1 - 0.00035 20.4 0.3 0.041 13.7 0.0 2.2 1 1 1 2 2 2 2 SOR/SNZ family DHO_dh PF01180.21 EGF77959.1 - 0.0084 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EGF77959.1 - 0.027 13.9 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 EGF77959.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 EGF77959.1 - 0.046 12.7 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NMO PF03060.15 EGF77959.1 - 0.06 12.7 0.0 0.92 8.8 0.0 2.1 1 1 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.17 EGF77959.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF1283 PF06932.11 EGF77960.1 - 0.41 10.9 10.2 0.82 9.9 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) FAP PF07174.11 EGF77963.1 - 0.043 13.3 13.0 0.048 13.1 13.0 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Mito_fiss_reg PF05308.11 EGF77963.1 - 4.8 7.2 10.8 7.5 6.6 10.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Lsm_interact PF05391.11 EGF77964.1 - 1.5 8.4 4.4 1.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Lsm interaction motif 4F5 PF04419.14 EGF77966.1 - 2.2e-10 41.2 4.4 2.2e-10 41.2 4.4 2.1 2 0 0 2 2 2 1 4F5 protein family PRP21_like_P PF12230.8 EGF77967.1 - 3.5e-43 148.0 6.5 3.5e-43 148.0 6.5 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGF77967.1 - 2.2e-39 133.2 2.9 3e-20 71.9 0.2 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EGF77967.1 - 1.2e-05 25.0 0.0 3.4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGF77967.1 - 0.014 15.8 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain zf_UBZ PF18439.1 EGF77967.1 - 0.15 11.6 0.1 0.4 10.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger RNF220 PF15926.5 EGF77967.1 - 0.18 11.4 1.8 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Toprim_Crpt PF13342.6 EGF77967.1 - 0.57 10.2 1.9 2.6 8.1 0.3 2.4 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase DUF5102 PF17104.5 EGF77968.1 - 7.5e-17 62.3 15.1 2.2e-11 44.4 0.1 3.6 2 1 1 3 3 3 3 Domain of unknown function (DUF5102) DSS1_SEM1 PF05160.13 EGF77968.1 - 1.2 9.3 7.2 4.1 7.5 7.2 2.0 1 0 0 1 1 1 0 DSS1/SEM1 family PRP38 PF03371.15 EGF77969.1 - 1.8e-49 167.9 0.0 2.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Brix PF04427.18 EGF77970.1 - 4.8e-43 147.5 0.3 7.8e-43 146.8 0.3 1.3 1 0 0 1 1 1 1 Brix domain CNDH2_C PF16858.5 EGF77970.1 - 0.0055 16.6 14.3 0.0084 16.0 14.3 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 EGF77970.1 - 0.024 14.0 18.9 0.032 13.6 18.9 1.3 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EGF77970.1 - 0.056 13.0 18.4 0.081 12.5 18.4 1.4 1 0 0 1 1 1 0 PPP4R2 CSRNP_N PF16019.5 EGF77970.1 - 0.086 12.8 7.7 0.17 11.8 7.7 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus XRN_M PF17846.1 EGF77970.1 - 0.28 10.1 5.9 0.36 9.7 5.9 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF4407 PF14362.6 EGF77970.1 - 2 7.7 8.0 2.5 7.4 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4746 PF15928.5 EGF77970.1 - 3.7 6.9 12.8 5.1 6.4 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TB2_DP1_HVA22 PF03134.19 EGF77971.1 - 5.8e-31 106.3 5.3 9e-31 105.6 5.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TRI9 PF08195.11 EGF77971.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 TRI9 protein DUF5090 PF17009.5 EGF77971.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) Pkinase PF00069.25 EGF77972.1 - 2.3e-54 184.5 0.0 3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77972.1 - 1.7e-21 76.7 0.0 2.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF77972.1 - 0.00022 20.1 0.0 0.00024 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF77972.1 - 0.0037 16.6 0.1 0.0055 16.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF77972.1 - 0.13 12.2 0.3 0.22 11.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF77972.1 - 0.2 10.9 0.0 0.4 9.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Cid2 PF09774.9 EGF77973.1 - 8.7e-14 52.3 5.4 8.7e-14 52.3 5.4 3.1 3 1 0 3 3 3 1 Caffeine-induced death protein 2 DUF5392 PF17370.2 EGF77973.1 - 0.25 11.4 1.3 0.92 9.6 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5392) HYLS1_C PF15311.6 EGF77974.1 - 4.7e-09 36.9 4.9 8.5e-05 23.2 0.5 2.6 2 0 0 2 2 2 2 Hydrolethalus syndrome protein 1 C-terminus ATP_bind_3 PF01171.20 EGF77975.1 - 1.7e-18 67.0 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EGF77975.1 - 2e-17 62.4 5.2 2e-17 62.4 5.2 2.6 3 0 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EGF77975.1 - 0.048 12.4 0.0 0.082 11.7 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 EGF77975.1 - 0.095 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Polysacc_deac_1 PF01522.21 EGF77976.1 - 9e-28 96.7 0.0 1.5e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase UBA_6 PF18039.1 EGF77976.1 - 0.12 12.4 0.1 13 5.8 0.0 2.8 2 0 0 2 2 2 0 UBA-like domain Rad17 PF03215.15 EGF77977.1 - 1.2e-28 100.3 0.0 2.6e-26 92.7 0.0 2.5 1 1 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGF77977.1 - 0.004 17.1 0.3 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 EGF77977.1 - 0.004 17.6 0.0 0.02 15.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF77977.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EGF77977.1 - 0.064 13.7 0.0 0.57 10.6 0.0 2.6 3 0 0 3 3 3 0 RNA helicase ATPase_2 PF01637.18 EGF77977.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGF77977.1 - 0.1 12.8 0.0 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGF77977.1 - 0.61 10.6 3.3 1.3 9.5 0.1 3.1 2 1 0 3 3 3 0 ABC transporter Ank_2 PF12796.7 EGF77978.1 - 3.5e-23 82.0 0.1 1.4e-14 54.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF77978.1 - 1.1e-22 79.8 0.8 7.5e-08 32.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGF77978.1 - 2e-22 79.3 1.2 2.3e-11 44.0 0.2 2.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF77978.1 - 2.1e-20 70.6 0.4 2.9e-05 24.1 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGF77978.1 - 7.2e-19 67.3 3.6 1.8e-05 25.0 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat Ribosomal_L6 PF00347.23 EGF77979.1 - 4.1e-26 91.5 0.1 2.9e-10 40.7 0.0 3.9 4 0 0 4 4 4 3 Ribosomal protein L6 MBOAT PF03062.19 EGF77980.1 - 3.9e-40 138.3 26.3 3.9e-40 138.3 26.3 1.6 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family GDC-P PF02347.16 EGF77981.1 - 4.2e-197 655.2 0.9 1.1e-188 627.4 0.2 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGF77981.1 - 1.1e-06 27.9 0.6 0.002 17.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGF77981.1 - 7.1e-05 22.2 0.0 0.00019 20.8 0.0 1.7 1 0 0 1 1 1 1 Beta-eliminating lyase NAD_binding_1 PF00175.21 EGF77982.1 - 1.8e-24 86.5 0.0 2.6e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGF77982.1 - 7.1e-11 42.3 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGF77982.1 - 7.7e-06 26.1 0.1 0.00013 22.1 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain W2 PF02020.18 EGF77983.1 - 1.7e-20 72.9 0.5 4.5e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon CCDC84 PF14968.6 EGF77984.1 - 1.2e-14 54.7 9.1 1.5e-14 54.4 9.1 1.2 1 0 0 1 1 1 1 Coiled coil protein 84 SUI1 PF01253.22 EGF77984.1 - 1.7 9.2 3.9 13 6.4 0.0 3.2 3 1 0 3 3 3 0 Translation initiation factor SUI1 WD40 PF00400.32 EGF77985.1 - 9.7e-23 80.0 22.8 0.00071 20.3 0.0 10.2 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF77985.1 - 1.3e-07 31.8 0.0 0.55 10.6 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF77985.1 - 0.00014 21.0 1.0 0.42 9.5 0.0 4.5 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF77985.1 - 0.00038 19.2 12.2 0.14 10.8 1.0 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PDDEXK_3 PF13366.6 EGF77985.1 - 0.041 14.2 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Ribosomal_L39 PF00832.20 EGF77986.1 - 5.6e-20 70.7 12.2 6.8e-20 70.4 12.2 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein ABC2_membrane PF01061.24 EGF77988.1 - 1.8e-42 145.2 19.0 1.8e-42 145.2 19.0 1.9 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EGF77988.1 - 3.6e-27 95.6 0.0 6.8e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGF77988.1 - 2e-06 27.1 21.5 4.5e-06 26.0 21.5 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGF77988.1 - 7.1e-05 22.8 0.6 0.14 12.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGF77988.1 - 0.00065 19.6 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF77988.1 - 0.0078 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EGF77988.1 - 0.03 14.6 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGF77988.1 - 0.034 14.7 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGF77988.1 - 0.051 13.0 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EGF77988.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF77988.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EGF77988.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane_2 PF12679.7 EGF77988.1 - 0.17 11.1 14.2 0.43 9.8 14.2 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_22 PF13401.6 EGF77988.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF77988.1 - 0.25 11.1 0.2 0.41 10.3 0.2 1.2 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.6 EGF77989.1 - 1.3e-15 57.3 5.4 2.7e-05 24.3 0.1 5.3 4 1 2 6 6 6 3 PPR repeat family PPR PF01535.20 EGF77989.1 - 1e-08 34.9 9.5 0.013 15.7 0.4 6.6 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 EGF77989.1 - 1.2e-06 28.0 0.9 0.27 10.5 0.0 3.2 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGF77989.1 - 3.3e-06 27.1 5.7 0.0056 16.7 1.4 5.2 3 1 2 5 5 5 2 Pentatricopeptide repeat domain TPR_15 PF13429.6 EGF77989.1 - 0.0087 15.3 0.1 0.042 13.1 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF77989.1 - 0.085 13.4 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PDCD2_C PF04194.13 EGF77990.1 - 8e-40 136.8 0.6 2.2e-39 135.3 0.3 1.8 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CAP59_mtransfer PF11735.8 EGF77991.1 - 1.4e-51 175.6 0.2 7e-51 173.2 0.2 1.9 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Pkinase PF00069.25 EGF77992.1 - 6.6e-43 147.0 0.1 3e-30 105.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF77992.1 - 1.4e-17 63.8 0.0 3.2e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF77992.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF77992.1 - 0.065 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S9_N PF02897.15 EGF77993.1 - 3.3e-74 250.1 3.5 4.3e-74 249.8 3.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGF77993.1 - 5e-58 196.1 0.3 4.1e-57 193.1 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Kinesin PF00225.23 EGF77994.1 - 2.4e-89 299.6 0.0 2.6e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF77994.1 - 9.5e-29 100.3 0.0 1.9e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_19 PF13245.6 EGF77994.1 - 0.047 14.0 1.9 0.24 11.7 1.9 2.0 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EGF77994.1 - 0.061 12.5 0.2 0.094 11.9 0.2 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 EGF77994.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 EGF77995.1 - 2.3e-64 217.6 56.9 2e-50 171.7 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF77995.1 - 2.4e-12 46.4 26.5 9.8e-12 44.5 26.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGF77995.1 - 7.8e-12 44.7 23.2 6.3e-08 31.9 8.0 3.1 1 1 2 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 EGF77995.1 - 5.9e-06 25.1 1.3 5.9e-06 25.1 1.3 3.2 2 1 1 3 3 3 1 MFS/sugar transport protein OATP PF03137.20 EGF77995.1 - 8.1e-06 24.4 4.5 8.1e-06 24.4 4.5 4.1 1 1 3 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 EGF77995.1 - 0.0005 19.0 18.8 0.0035 16.2 3.6 3.5 2 2 1 3 3 3 3 LacY proton/sugar symporter MFS_4 PF06779.14 EGF77995.1 - 0.00059 19.2 20.4 0.0081 15.5 7.1 3.0 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EGF77995.1 - 0.0006 18.3 14.3 0.00078 18.0 1.2 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector UCH PF00443.29 EGF77996.1 - 1.7e-54 185.1 5.5 2.1e-54 184.7 5.5 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF77996.1 - 9.8e-36 124.0 10.4 1.2e-35 123.7 10.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TrwB_AAD_bind PF10412.9 EGF77996.1 - 0.016 14.1 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF4205 PF13898.6 EGF77996.1 - 0.019 13.9 0.4 0.026 13.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) Med25 PF11232.8 EGF77996.1 - 0.087 12.8 0.5 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 ASH PF15780.5 EGF77997.1 - 2.1e-35 120.8 14.4 2.6e-05 24.4 0.0 10.5 11 0 0 11 11 11 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGF77997.1 - 8.9e-16 57.7 10.1 0.00073 19.4 0.1 9.1 9 0 0 9 9 9 4 MSP (Major sperm protein) domain MYCBPAP PF14646.6 EGF77997.1 - 1.4e-08 34.1 2.6 0.0032 16.5 0.1 5.7 5 2 1 6 6 6 3 MYCBP-associated protein family PapD-like PF14874.6 EGF77997.1 - 0.014 15.6 2.0 21 5.4 0.0 4.6 6 0 0 6 6 6 0 Flagellar-associated PapD-like Aminotran_4 PF01063.19 EGF77998.1 - 5.3e-31 108.2 0.0 6.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DRMBL PF07522.14 EGF77999.1 - 1e-10 41.7 0.2 4.5e-10 39.7 0.2 2.1 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGF77999.1 - 4.7e-09 36.1 0.2 1.1e-07 31.5 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGF77999.1 - 0.0025 17.9 0.1 0.0058 16.7 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily ATP-synt PF00231.19 EGF78000.1 - 1e-72 245.2 6.2 1.2e-72 245.0 6.2 1.0 1 0 0 1 1 1 1 ATP synthase RasGEF PF00617.19 EGF78001.1 - 3.6e-45 154.3 0.6 3.6e-45 154.3 0.6 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGF78001.1 - 5.9e-15 55.4 1.1 2.2e-14 53.6 0.0 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF4483 PF14825.6 EGF78002.1 - 1.8e-47 161.0 0.9 3.3e-47 160.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) TP_methylase PF00590.20 EGF78003.1 - 2.3e-21 76.7 0.0 3.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases GFO_IDH_MocA PF01408.22 EGF78003.1 - 0.085 13.7 0.1 0.27 12.1 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold FucT_N PF18025.1 EGF78003.1 - 0.11 13.0 0.1 0.47 10.9 0.0 2.1 1 1 1 2 2 2 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain NDUF_B7 PF05676.13 EGF78005.1 - 6e-28 96.4 6.4 7.8e-28 96.0 6.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGF78005.1 - 0.00013 22.0 4.5 0.00015 21.7 4.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SAS4 PF15460.6 EGF78005.1 - 0.025 14.7 4.5 0.05 13.7 2.8 1.9 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 EFhand_Ca_insen PF08726.10 EGF78005.1 - 0.027 14.6 0.5 0.063 13.4 0.1 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand CX9C PF16860.5 EGF78005.1 - 0.099 12.7 2.5 2 8.5 0.2 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Interfer-bind PF09294.10 EGF78005.1 - 0.11 12.9 0.9 0.16 12.3 0.2 1.6 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Wbp11 PF09429.10 EGF78006.1 - 2.9e-17 62.8 11.4 2.9e-17 62.8 11.4 2.7 3 0 0 3 3 3 1 WW domain binding protein 11 NSP2-B_epitope PF14757.6 EGF78006.1 - 0.83 9.3 7.2 13 5.4 5.7 2.2 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Pribosyltran PF00156.27 EGF78007.1 - 3.2e-23 82.0 0.0 4.2e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EGF78007.1 - 0.0017 17.9 0.1 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase UPRTase PF14681.6 EGF78007.1 - 0.048 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Tim44 PF04280.15 EGF78008.1 - 4.8e-16 59.2 0.2 6.9e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 EGF78008.1 - 2.7e-12 46.2 0.1 3.2e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 MBA1-like protein S1 PF00575.23 EGF78009.1 - 1.5e-54 182.3 21.5 1.1e-08 35.2 0.0 12.2 12 1 0 12 12 12 8 S1 RNA binding domain Suf PF05843.14 EGF78009.1 - 2.5e-08 34.3 26.1 4.2e-05 23.7 0.1 4.3 1 1 3 4 4 3 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EGF78009.1 - 3.4e-08 33.0 0.5 2.7e-05 23.5 0.8 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78009.1 - 1e-05 25.9 0.0 1.2 10.1 0.0 5.1 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF78009.1 - 1.1e-05 25.9 0.0 0.019 15.5 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EGF78009.1 - 0.00065 18.9 5.5 0.52 9.4 0.3 3.2 2 1 0 3 3 3 2 NRDE-2, necessary for RNA interference YL1 PF05764.13 EGF78009.1 - 0.0038 17.4 16.7 0.0038 17.4 16.7 2.2 2 0 0 2 2 2 1 YL1 nuclear protein TPR_17 PF13431.6 EGF78009.1 - 0.018 15.4 0.1 14 6.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.9 EGF78009.1 - 0.019 14.5 10.6 0.041 13.5 10.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HYR PF02494.16 EGF78009.1 - 0.077 13.3 0.6 14 6.1 0.1 4.5 5 0 0 5 5 4 0 HYR domain DUF1269 PF06897.12 EGF78009.1 - 0.096 13.0 0.1 0.41 11.0 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1269) RPN7 PF10602.9 EGF78009.1 - 0.12 12.0 1.7 0.95 9.1 1.3 2.4 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_8 PF13181.6 EGF78009.1 - 0.12 12.6 0.4 16 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TAF1_subA PF14929.6 EGF78009.1 - 0.15 11.5 2.2 0.6 9.5 2.2 1.8 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_2 PF07719.17 EGF78009.1 - 0.2 11.9 0.1 8.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF78009.1 - 0.22 12.2 0.2 7 7.5 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Nop14 PF04147.12 EGF78009.1 - 1.9 6.6 17.8 3.5 5.7 17.8 1.3 1 0 0 1 1 1 0 Nop14-like family MMU163 PF17119.5 EGF78009.1 - 3.3 6.8 5.4 8 5.5 5.4 1.6 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CDC45 PF02724.14 EGF78009.1 - 5.2 5.2 19.7 0.62 8.3 15.4 1.5 2 0 0 2 2 2 0 CDC45-like protein CCDC106 PF15794.5 EGF78009.1 - 9.6 5.8 11.7 25 4.5 11.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PPP1R35_C PF15503.6 EGF78010.1 - 1.3 8.8 5.8 0.35 10.7 1.0 2.4 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus EF_TS PF00889.19 EGF78011.1 - 1.8e-17 63.7 0.2 4.3e-15 55.9 0.0 2.4 1 1 1 2 2 2 2 Elongation factor TS FeS_assembly_P PF01883.19 EGF78012.1 - 1.1e-12 48.0 0.2 1.8e-12 47.3 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Molydop_binding PF01568.21 EGF78012.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain Ribosomal_L32p PF01783.23 EGF78013.1 - 3.2e-10 40.1 4.2 3.7e-10 39.9 4.2 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.12 EGF78013.1 - 0.013 15.5 0.7 0.015 15.3 0.7 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-RING_5 PF14634.6 EGF78013.1 - 0.14 12.1 3.4 5.3 7.1 0.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain TF_Zn_Ribbon PF08271.12 EGF78013.1 - 0.16 11.5 1.2 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EGF78013.1 - 0.89 9.1 4.9 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 EGF78013.1 - 7.2 6.7 6.8 1.7 8.7 0.2 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger DHC_N1 PF08385.12 EGF78014.1 - 1.1e-160 536.1 9.8 1.1e-160 536.1 9.8 4.5 4 1 2 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGF78014.1 - 8.2e-155 514.7 0.0 4.9e-152 505.6 0.0 3.2 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF78014.1 - 8.6e-135 449.9 11.7 8.6e-135 449.9 11.7 5.5 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGF78014.1 - 2.4e-103 345.0 5.3 6.5e-102 340.3 0.0 3.7 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGF78014.1 - 1.5e-97 326.5 0.0 5.3e-96 321.5 0.0 3.3 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGF78014.1 - 1.6e-88 295.5 2.1 2.8e-87 291.5 0.2 3.7 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF78014.1 - 1.1e-71 240.1 1.0 3.9e-67 225.3 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF78014.1 - 1.6e-56 190.6 0.2 4.9e-56 189.0 0.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF78014.1 - 5e-54 183.6 10.2 9.8e-54 182.6 10.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGF78014.1 - 3.5e-45 152.9 0.0 2.2e-42 143.9 0.0 4.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGF78014.1 - 5.2e-31 107.5 0.0 1.4e-11 44.6 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGF78014.1 - 3.2e-30 104.8 0.6 1.3e-29 102.9 0.2 2.4 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGF78014.1 - 6.6e-19 68.0 3.5 1.3e-17 63.8 0.2 3.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 EGF78014.1 - 1.4e-08 35.1 0.1 0.14 12.5 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 EGF78014.1 - 6.3e-06 26.8 0.1 0.3 11.6 0.0 4.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGF78014.1 - 3.5e-05 24.2 10.1 1.6 9.1 0.0 7.0 7 0 0 7 7 6 1 AAA ATPase domain AAA PF00004.29 EGF78014.1 - 9.4e-05 22.9 13.2 0.072 13.5 0.0 6.8 9 0 0 9 9 7 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGF78014.1 - 0.00023 20.4 0.7 0.073 12.1 0.0 3.6 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGF78014.1 - 0.00095 18.9 4.6 0.16 11.8 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EGF78014.1 - 0.0013 18.5 0.1 4.6 6.9 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EGF78014.1 - 0.0043 17.2 0.2 5 7.3 0.0 4.5 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGF78014.1 - 0.0054 16.5 0.4 15 5.3 0.2 3.7 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGF78014.1 - 0.0072 16.2 0.4 3.6 7.5 0.1 3.2 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGF78014.1 - 0.0077 15.6 0.2 0.099 12.0 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family TsaE PF02367.17 EGF78014.1 - 0.011 15.7 1.3 1.7 8.7 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGF78014.1 - 0.013 16.1 5.8 0.25 11.8 0.1 4.5 4 0 0 4 4 2 0 ABC transporter Mg_chelatase PF01078.21 EGF78014.1 - 0.014 14.8 0.1 2.2 7.6 0.0 4.2 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 EGF78014.1 - 0.027 14.7 0.9 1.8 8.8 0.1 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EGF78014.1 - 0.027 14.2 0.2 10 5.9 0.0 3.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EGF78014.1 - 0.038 14.4 0.7 53 4.3 0.0 4.1 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.6 EGF78014.1 - 0.13 12.6 1.8 29 5.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EGF78014.1 - 0.15 12.2 0.4 12 6.0 0.1 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EGF78014.1 - 0.33 11.1 3.1 36 4.5 0.1 3.8 3 0 0 3 3 3 0 AAA domain T3SSipB PF16535.5 EGF78014.1 - 1 9.8 28.8 1.3 9.5 0.1 5.4 5 0 0 5 5 4 0 Type III cell invasion protein SipB DUF4201 PF13870.6 EGF78014.1 - 6.3 6.5 19.0 0.61 9.8 7.8 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) WD40 PF00400.32 EGF78015.1 - 5.3e-24 84.0 21.5 8.7e-06 26.4 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.6 EGF78015.1 - 8.6e-06 26.1 7.4 0.0023 18.4 0.7 4.6 5 1 1 6 6 6 2 PQQ-like domain Nucleoporin_N PF08801.11 EGF78015.1 - 1.1e-05 24.4 2.5 0.0017 17.2 0.3 3.4 1 1 2 3 3 3 1 Nup133 N terminal like Sina PF03145.16 EGF78015.1 - 1.7e-05 24.9 1.5 2.8e-05 24.2 1.5 1.3 1 0 0 1 1 1 1 Seven in absentia protein family Nup160 PF11715.8 EGF78015.1 - 0.0024 16.6 4.7 1 7.9 0.1 3.7 3 1 0 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGF78015.1 - 0.1 11.9 0.0 13 5.0 0.0 2.2 1 1 0 2 2 2 0 WD40-like domain zf-TRAF PF02176.18 EGF78015.1 - 0.98 10.2 6.6 2.3 9.0 4.6 2.6 1 1 1 2 2 2 0 TRAF-type zinc finger TIP49 PF06068.13 EGF78016.1 - 3.8e-166 552.6 0.6 4.9e-166 552.2 0.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGF78016.1 - 2e-22 79.1 0.2 5.6e-22 77.6 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGF78016.1 - 1.7e-10 41.4 0.2 7.7e-06 26.4 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGF78016.1 - 5.7e-10 39.2 0.1 1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF78016.1 - 7.7e-06 26.2 0.1 0.044 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGF78016.1 - 7.5e-05 23.2 0.1 0.0027 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGF78016.1 - 0.00031 20.8 0.1 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGF78016.1 - 0.00034 20.9 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGF78016.1 - 0.00074 19.1 0.7 0.0017 18.0 0.2 1.8 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGF78016.1 - 0.004 16.9 0.1 3.5 7.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGF78016.1 - 0.0042 16.5 0.2 0.19 11.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGF78016.1 - 0.0048 17.2 0.2 4.8 7.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGF78016.1 - 0.0073 16.8 0.0 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGF78016.1 - 0.013 15.5 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGF78016.1 - 0.034 13.9 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGF78016.1 - 0.04 14.1 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGF78016.1 - 0.043 13.8 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 EGF78016.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 EGF78016.1 - 0.054 13.0 0.1 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGF78016.1 - 0.069 12.4 0.2 0.22 10.8 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 EGF78016.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TEX12 PF15219.6 EGF78016.1 - 0.17 12.2 0.5 2 8.8 0.1 2.6 3 0 0 3 3 3 0 Testis-expressed 12 DUF4246 PF14033.6 EGF78017.1 - 5.8e-30 104.8 0.0 7.3e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HU-CCDC81_euk_2 PF18289.1 EGF78019.1 - 2.2e-14 53.4 1.2 4.2e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 EGF78019.1 - 0.0005 20.2 0.1 0.002 18.2 0.0 2.0 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 DUF922 PF06037.11 EGF78019.1 - 0.14 11.9 6.3 0.027 14.2 1.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) MMtag PF10159.9 EGF78020.1 - 9e-11 41.9 15.7 2.4e-10 40.6 2.7 3.6 2 2 0 2 2 2 1 Multiple myeloma tumor-associated DNA_pol_A_exo1 PF01612.20 EGF78021.1 - 7.3e-47 159.3 0.4 1.3e-46 158.5 0.4 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EGF78021.1 - 8.9e-16 58.4 1.1 4.4e-15 56.1 1.1 2.3 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 EGF78021.1 - 2.3e-13 49.9 0.0 4.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Prp18 PF02840.15 EGF78022.1 - 1.7e-62 209.7 0.6 2.6e-62 209.1 0.2 1.5 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EGF78022.1 - 2.2e-11 43.1 3.5 4.1e-11 42.2 3.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ada3 PF10198.9 EGF78022.1 - 0.089 12.9 6.1 0.98 9.6 6.1 2.3 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 GPP34 PF05719.11 EGF78023.1 - 8.8e-55 185.9 0.1 1.2e-54 185.5 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) UPF0181 PF03701.14 EGF78023.1 - 0.27 10.9 0.8 0.6 9.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Semialdhyde_dhC PF02774.18 EGF78024.1 - 1.6e-39 135.9 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGF78024.1 - 2.1e-24 86.3 0.0 3.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGF78024.1 - 0.0036 17.4 0.2 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 EGF78024.1 - 0.0044 17.7 0.2 0.013 16.2 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase ubiquitin PF00240.23 EGF78025.1 - 4.8e-07 29.4 0.4 2.6e-06 27.1 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGF78025.1 - 0.00018 21.9 0.1 0.0009 19.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Pkinase PF00069.25 EGF78026.1 - 4.1e-06 26.3 0.0 0.0011 18.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Vac14_Fab1_bd PF12755.7 EGF78026.1 - 2.2e-05 25.0 0.0 0.96 10.1 0.0 3.5 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGF78026.1 - 4.1e-05 23.5 0.0 0.94 9.9 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGF78026.1 - 4.5e-05 23.5 0.0 0.19 11.7 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 FAM76 PF16046.5 EGF78027.1 - 3.5 6.9 8.3 5 6.4 8.3 1.3 1 1 0 1 1 1 0 FAM76 protein Cyt-b5 PF00173.28 EGF78028.1 - 7.1e-13 48.5 0.2 9e-13 48.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain G10 PF01125.17 EGF78029.1 - 6.1e-67 223.9 6.5 6.8e-67 223.8 6.5 1.0 1 0 0 1 1 1 1 G10 protein DUF4201 PF13870.6 EGF78030.1 - 4.5e-41 140.5 24.7 4.5e-41 140.5 24.7 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) 6PGD PF00393.19 EGF78031.1 - 3.4e-128 427.0 0.0 4.2e-128 426.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGF78031.1 - 4.7e-51 173.1 0.0 6.6e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGF78031.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGF78031.1 - 0.034 14.7 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoatB PF10389.9 EGF78031.1 - 0.13 12.2 3.2 0.82 9.6 0.4 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B Vps26 PF03643.15 EGF78032.1 - 3.7e-129 429.6 2.1 4.5e-129 429.3 2.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 EGF78032.1 - 0.00042 20.8 0.0 0.088 13.3 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGF78032.1 - 0.018 15.1 2.7 1.2 9.2 0.0 3.3 2 1 2 5 5 5 0 Arrestin (or S-antigen), N-terminal domain RCC1 PF00415.18 EGF78033.1 - 2.4e-52 175.3 13.7 3.2e-14 53.3 0.0 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF78033.1 - 6e-28 96.0 24.1 8.5e-09 35.0 0.0 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EGF78033.1 - 0.0071 16.8 0.1 0.6 10.6 0.0 3.4 3 1 1 4 4 4 1 SUKH-3 immunity protein MRP-L46 PF11788.8 EGF78034.1 - 1e-14 55.3 0.0 1.6e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 E1-E2_ATPase PF00122.20 EGF78036.1 - 6.7e-49 165.9 1.2 6.7e-49 165.9 1.2 3.5 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGF78036.1 - 1.3e-45 155.3 8.6 1.3e-45 155.3 8.6 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGF78036.1 - 4.7e-23 82.6 0.0 1.8e-22 80.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF78036.1 - 3e-20 71.7 1.2 4.7e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGF78036.1 - 1.4e-19 70.0 0.0 3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGF78036.1 - 3.4e-07 30.3 0.9 3.5e-05 23.7 0.7 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGF78036.1 - 5.7e-07 30.1 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NDUFA12 PF05071.16 EGF78037.1 - 1.9e-11 44.7 0.6 7.6e-11 42.7 0.6 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DnaB_bind PF10410.9 EGF78037.1 - 0.013 15.7 0.2 0.025 14.8 0.2 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Tox-URI2 PF15653.6 EGF78038.1 - 0.0032 17.7 0.8 0.0065 16.7 0.8 1.5 1 0 0 1 1 1 1 URI fold toxin 2 PUB_1 PF18486.1 EGF78038.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain FAM76 PF16046.5 EGF78038.1 - 0.098 12.0 4.7 0.12 11.7 4.7 1.0 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 EGF78038.1 - 1.1 9.9 4.8 0.56 10.9 0.6 2.1 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 EGF78039.1 - 0.13 10.2 17.2 3.7 5.3 17.2 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CobT PF06213.12 EGF78039.1 - 0.21 11.0 7.8 0.39 10.0 7.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HEPN_Swt1 PF18731.1 EGF78039.1 - 0.6 10.5 5.2 1.5 9.2 1.1 2.2 2 0 0 2 2 2 0 Swt1-like HEPN Spore-coat_CotD PF11122.8 EGF78039.1 - 0.82 10.5 5.7 7.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Inner spore coat protein D Roughex PF06020.11 EGF78039.1 - 4.6 6.2 9.5 9.6 5.2 9.5 1.5 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 EGF78039.1 - 8.1 7.5 11.3 0.34 11.9 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) SNAD3 PF18749.1 EGF78040.1 - 0.018 14.2 1.1 0.023 13.9 1.1 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 DUF4175 PF13779.6 EGF78041.1 - 0.12 10.3 14.6 0.15 9.9 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CobT PF06213.12 EGF78041.1 - 0.23 10.8 12.3 0.5 9.7 12.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peroxin-13_N PF04088.13 EGF78041.1 - 0.71 10.1 3.4 2.8 8.2 0.2 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Spore-coat_CotD PF11122.8 EGF78041.1 - 1.2 10.0 5.1 3.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Inner spore coat protein D SLC12 PF03522.15 EGF78041.1 - 1.3 8.0 10.6 2.4 7.1 2.0 2.2 2 0 0 2 2 2 0 Solute carrier family 12 TFIIA PF03153.13 EGF78041.1 - 1.5 8.8 25.1 0.91 9.4 16.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 EGF78041.1 - 2 6.2 16.6 1.5 6.7 4.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CPSF100_C PF13299.6 EGF78041.1 - 2.7 8.2 9.9 0.078 13.2 2.0 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGF78041.1 - 3.5 6.8 5.6 2.3 7.4 0.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter FAM176 PF14851.6 EGF78041.1 - 4.5 6.9 10.6 0.14 11.8 1.7 2.5 2 1 0 2 2 2 0 FAM176 family Suf PF05843.14 EGF78041.1 - 4.5 7.2 14.3 0.56 10.1 7.6 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Rxt3 PF08642.10 EGF78041.1 - 4.7 8.0 6.2 0.43 11.4 0.4 2.0 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 Pex14_N PF04695.13 EGF78041.1 - 7.8 7.1 17.3 0.12 13.1 8.1 2.3 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_32 PF13654.6 EGF78042.1 - 0.1 11.3 7.0 0.18 10.5 7.0 1.4 1 1 0 1 1 1 0 AAA domain Guanylin PF02058.15 EGF78042.1 - 0.18 12.3 5.6 0.18 12.3 1.2 2.8 2 1 1 3 3 3 0 Guanylin precursor Tropomyosin_1 PF12718.7 EGF78042.1 - 0.6 10.3 11.7 0.14 12.3 6.1 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF2072 PF09845.9 EGF78042.1 - 0.78 10.0 5.2 0.14 12.5 0.7 2.0 2 1 0 2 2 2 0 Zn-ribbon containing protein TMPIT PF07851.13 EGF78042.1 - 0.96 8.6 13.6 0.3 10.3 2.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein Peptidase_S41 PF03572.18 EGF78043.1 - 9.8e-12 44.7 0.0 2.2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 ATP-synt_D PF01813.17 EGF78044.1 - 0.0024 17.7 3.1 0.0063 16.4 0.0 2.0 2 0 0 2 2 2 1 ATP synthase subunit D T3SSipB PF16535.5 EGF78044.1 - 0.0088 16.5 4.1 0.0088 16.5 4.1 1.5 2 0 0 2 2 1 1 Type III cell invasion protein SipB Exonuc_VII_L PF02601.15 EGF78044.1 - 0.063 12.8 2.1 0.081 12.5 2.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EGF78044.1 - 0.47 10.5 3.2 13 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 EGF78044.1 - 0.67 10.7 4.0 0.78 10.5 2.9 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) BRE1 PF08647.11 EGF78044.1 - 0.99 9.5 17.8 1 9.5 3.6 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CAF1A PF12253.8 EGF78044.1 - 1.6 9.0 10.4 0.75 10.0 4.3 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A CENP-H PF05837.12 EGF78044.1 - 1.6 9.2 8.3 3 8.3 8.3 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 EGF78044.1 - 2.1 7.1 13.9 3.4 6.4 13.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Trypan_PARP PF05887.11 EGF78044.1 - 3.1 7.8 8.1 0.97 9.4 4.9 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Med9 PF07544.13 EGF78044.1 - 7.6 6.7 13.6 7 6.8 4.0 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3481 PF11980.8 EGF78045.1 - 0.022 14.4 0.0 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein BRE1 PF08647.11 EGF78045.1 - 0.15 12.2 4.3 0.17 11.9 3.2 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase GPS2_interact PF15784.5 EGF78045.1 - 0.64 10.5 3.6 0.31 11.5 0.9 1.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain APG6_N PF17675.1 EGF78045.1 - 2 9.0 12.2 1.6 9.3 1.3 2.5 3 0 0 3 3 3 0 Apg6 coiled-coil region MAD PF05557.13 EGF78046.1 - 0.0057 15.1 6.9 0.0094 14.4 6.9 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.9 EGF78046.1 - 0.0072 16.6 9.2 0.013 15.8 9.2 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EGF78046.1 - 0.05 14.1 6.7 0.037 14.5 5.2 1.5 2 0 0 2 2 2 0 Fez1 Cep57_CLD PF14073.6 EGF78046.1 - 0.083 12.9 13.7 1 9.4 2.3 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 Pil1 PF13805.6 EGF78046.1 - 0.15 11.5 3.8 0.28 10.6 3.8 1.4 1 0 0 1 1 1 0 Eisosome component PIL1 DUF1664 PF07889.12 EGF78046.1 - 0.2 11.7 2.4 0.39 10.8 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EGF78046.1 - 0.46 10.9 6.6 1.3 9.5 0.2 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EGF78046.1 - 2.2 7.4 8.8 3.1 7.0 8.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EGF78046.1 - 5.3 5.5 7.9 7.4 5.0 7.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A P68HR PF08061.11 EGF78046.1 - 8.2 6.7 7.5 22 5.3 0.6 2.3 2 0 0 2 2 2 0 P68HR (NUC004) repeat Bap31_Bap29_C PF18035.1 EGF78047.1 - 0.049 13.6 0.4 0.049 13.6 0.4 2.6 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain TMPIT PF07851.13 EGF78047.1 - 1.1 8.4 6.3 0.39 9.9 3.5 1.6 2 0 0 2 2 2 0 TMPIT-like protein BAR_3_WASP_bdg PF10456.9 EGF78048.1 - 0.017 14.6 1.4 0.055 12.9 0.2 2.1 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein FANCI_HD1 PF14679.6 EGF78048.1 - 0.021 14.8 0.6 0.064 13.2 0.2 1.9 2 0 0 2 2 2 0 FANCI helical domain 1 Spc7 PF08317.11 EGF78048.1 - 0.032 13.1 2.6 0.051 12.4 2.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RapA_C PF12137.8 EGF78048.1 - 0.077 12.0 0.9 0.1 11.6 0.9 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Med30 PF11315.8 EGF78048.1 - 0.17 12.1 1.6 0.35 11.1 1.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 TACC_C PF05010.14 EGF78048.1 - 0.4 10.4 8.2 0.18 11.6 3.1 2.2 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal V_ATPase_I PF01496.19 EGF78048.1 - 0.6 8.0 3.0 0.95 7.3 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RCC1 PF00415.18 EGF78050.1 - 5.7e-23 81.3 9.7 2.3e-06 28.1 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGF78050.1 - 3.7e-18 65.8 0.5 5e-09 36.4 0.0 4.3 2 2 1 3 3 3 3 BTB/POZ domain RCC1_2 PF13540.6 EGF78050.1 - 1.1e-14 53.8 10.8 2.3e-07 30.4 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BACK PF07707.15 EGF78050.1 - 0.031 14.4 1.7 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 BTB And C-terminal Kelch DUF1459 PF07312.11 EGF78050.1 - 3.3 8.0 11.8 5.6 7.3 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1459) RNB PF00773.19 EGF78051.1 - 6.5e-60 203.2 0.0 1.2e-59 202.3 0.0 1.4 1 1 0 1 1 1 1 RNB domain mRNA_decap_C PF16741.5 EGF78051.1 - 0.35 10.2 0.0 0.35 10.2 0.0 2.2 3 0 0 3 3 3 0 mRNA-decapping enzyme C-terminus tRNA-synt_2 PF00152.20 EGF78052.1 - 2.6e-79 266.6 0.0 4.3e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGF78052.1 - 3.6e-10 39.7 0.1 1e-09 38.2 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 EGF78052.1 - 0.047 13.3 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like tRNA-synt_2d PF01409.20 EGF78052.1 - 0.056 12.9 0.1 0.73 9.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SNF2_N PF00176.23 EGF78053.1 - 2.2e-56 191.1 1.1 3.4e-56 190.5 1.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF78053.1 - 9.1e-20 71.1 0.0 4.7e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF78053.1 - 9.1e-08 32.3 0.0 2.8e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGF78053.1 - 4.3e-07 29.4 0.0 9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ANTH PF07651.16 EGF78054.1 - 3.6e-66 223.0 0.0 3.6e-66 223.0 0.0 3.2 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EGF78054.1 - 6.7e-49 166.1 17.1 6.7e-49 166.1 17.1 6.9 4 2 3 8 8 8 2 I/LWEQ domain Spc7 PF08317.11 EGF78054.1 - 0.00033 19.7 13.9 0.00033 19.7 13.9 4.3 2 1 2 4 4 4 1 Spc7 kinetochore protein YsaB PF13983.6 EGF78055.1 - 0.0069 16.7 1.1 0.011 16.1 1.1 1.3 1 0 0 1 1 1 1 YsaB-like lipoprotein PRKCSH-like PF12999.7 EGF78056.1 - 1.8e-36 125.6 8.0 1.8e-36 125.6 8.0 2.0 3 0 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGF78056.1 - 1.4e-24 86.5 0.2 3.6e-24 85.2 0.2 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EGF78056.1 - 3.7e-08 34.2 0.7 1.1e-07 32.7 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Terminase_6C PF17289.2 EGF78056.1 - 0.02 15.0 0.4 0.047 13.8 0.4 1.7 1 0 0 1 1 1 0 Terminase RNaseH-like domain HisKA PF00512.25 EGF78056.1 - 0.76 9.9 3.0 4 7.5 0.1 2.9 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Med6 PF04934.14 EGF78057.1 - 7.3e-38 129.4 1.4 1.1e-37 128.8 1.4 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF3342 PF11822.8 EGF78059.1 - 4.3e-18 65.3 1.3 8.8e-18 64.3 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) gag_pre-integrs PF13976.6 EGF78061.1 - 2.3e-07 30.5 0.0 5.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 EGF78061.1 - 0.00038 20.1 0.3 0.0008 19.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 EGF78061.1 - 0.081 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF78061.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Vac17 PF17321.2 EGF78061.1 - 0.11 11.9 0.5 1 8.7 0.4 2.1 2 0 0 2 2 2 0 Vacuole-related protein 17 YlbD_coat PF14071.6 EGF78062.1 - 0.23 11.7 10.4 0.03 14.6 5.2 2.1 1 1 1 2 2 2 0 Putative coat protein Histone_HNS PF00816.21 EGF78062.1 - 2.5 9.0 6.8 2.4 9.0 0.3 2.4 1 1 1 2 2 2 0 H-NS histone family Asp PF00026.23 EGF78063.1 - 1.5e-14 54.1 0.8 1.9e-14 53.8 0.2 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78063.1 - 2.3e-05 24.2 0.1 0.00038 20.3 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF742 PF05331.11 EGF78063.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Asp_protease_2 PF13650.6 EGF78063.1 - 0.11 13.2 0.2 0.69 10.6 0.2 2.3 3 0 0 3 3 3 0 Aspartyl protease Arm-DNA-bind_4 PF14657.6 EGF78064.1 - 0.03 14.1 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain PAG PF15347.6 EGF78067.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched PAG PF15347.6 EGF78070.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Asp PF00026.23 EGF78071.1 - 3.5e-11 43.1 0.0 7e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78071.1 - 0.00097 18.9 0.0 0.0048 16.7 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal HNH_2 PF13391.6 EGF78073.1 - 8.1e-06 25.9 0.1 0.00034 20.7 0.0 2.7 2 0 0 2 2 2 1 HNH endonuclease IFT57 PF10498.9 EGF78074.1 - 0.89 8.5 6.5 0.051 12.5 0.8 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Nucleo_P87 PF07267.11 EGF78074.1 - 6 5.6 9.5 68 2.1 9.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AAA PF00004.29 EGF78076.1 - 5.7e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF78076.1 - 0.0003 20.4 0.0 0.0008 19.0 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGF78076.1 - 0.0003 21.1 0.0 0.00069 20.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 EGF78076.1 - 0.0023 18.4 0.0 0.011 16.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGF78076.1 - 0.004 17.7 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TK PF00265.18 EGF78076.1 - 0.0068 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Thymidine kinase AAA_24 PF13479.6 EGF78076.1 - 0.0096 15.7 2.9 0.2 11.3 0.2 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGF78076.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 EGF78076.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGF78076.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGF78076.1 - 0.039 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGF78076.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF78076.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain APP_amyloid PF10515.9 EGF78077.1 - 0.0044 17.5 0.4 0.011 16.2 0.4 1.6 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus DUF1640 PF07798.11 EGF78077.1 - 0.069 13.2 1.0 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) TMEM51 PF15345.6 EGF78077.1 - 0.42 10.4 6.2 6.6 6.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3336 PF11815.8 EGF78080.1 - 1.4e-36 125.2 1.1 2.9e-35 121.0 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGF78080.1 - 5.3e-14 52.9 0.0 9.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase CMS1 PF14617.6 EGF78081.1 - 3.1e-19 69.3 0.6 5.1e-19 68.6 0.6 1.6 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit NYN PF01936.18 EGF78082.1 - 6.8e-25 88.3 0.0 1.6e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 NYN domain PIN_11 PF18479.1 EGF78082.1 - 0.094 12.9 0.0 0.56 10.4 0.0 2.3 3 0 0 3 3 3 0 PIN like domain DUF4045 PF13254.6 EGF78083.1 - 3.6 7.1 7.8 4.4 6.8 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAD-oxidase_C PF02913.19 EGF78084.1 - 4.6e-54 183.7 0.1 6.3e-54 183.2 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGF78084.1 - 8.3e-34 116.3 0.1 1.8e-33 115.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.26 EGF78085.1 - 4.5e-34 117.1 0.0 5.4e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EGF78085.1 - 0.004 16.8 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EGF78085.1 - 0.056 13.7 0.1 0.077 13.3 0.1 1.4 1 1 0 1 1 1 0 RWD domain CUE PF02845.16 EGF78086.1 - 6.6e-07 28.9 0.2 0.022 14.5 0.1 2.5 2 0 0 2 2 2 2 CUE domain DMA PF03474.14 EGF78086.1 - 0.00033 20.2 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 DMRTA motif AAA_6 PF12774.7 EGF78087.1 - 1.8e-163 543.1 0.0 1.3e-159 530.5 0.0 3.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF78087.1 - 1.6e-136 455.6 6.3 1.6e-136 455.6 6.3 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGF78087.1 - 1.5e-106 355.5 0.0 6.6e-106 353.4 0.0 2.3 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGF78087.1 - 5e-105 351.1 0.1 1.1e-103 346.7 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGF78087.1 - 1.5e-93 312.0 1.0 1.5e-93 312.0 1.0 3.4 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF78087.1 - 5e-78 260.8 2.1 1.6e-71 239.5 0.0 4.6 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF78087.1 - 8.9e-56 188.2 0.3 3.6e-54 183.0 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF78087.1 - 8.3e-51 173.0 11.1 8.3e-51 173.0 11.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGF78087.1 - 8.7e-42 142.0 0.0 4.3e-39 133.3 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGF78087.1 - 5.2e-27 94.5 1.9 2.2e-26 92.4 0.3 3.1 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGF78087.1 - 4.6e-22 78.5 0.1 2.7e-05 24.2 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGF78087.1 - 1.6e-21 76.4 0.0 8.5e-21 74.0 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EGF78087.1 - 6.1e-10 39.6 0.3 0.041 14.3 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF78087.1 - 7.1e-10 39.5 0.0 0.35 11.2 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGF78087.1 - 1.7e-07 31.6 0.6 0.69 10.2 0.0 5.3 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 EGF78087.1 - 3.6e-07 29.5 0.1 0.0037 16.4 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 EGF78087.1 - 2.1e-06 28.3 4.1 0.023 15.2 0.0 5.3 6 0 0 6 6 3 1 AAA domain RNA_helicase PF00910.22 EGF78087.1 - 7.1e-06 26.4 0.2 2.1 8.8 0.0 4.0 3 0 0 3 3 3 2 RNA helicase Sigma54_activat PF00158.26 EGF78087.1 - 9.1e-06 25.5 0.8 0.18 11.5 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EGF78087.1 - 0.00021 21.2 0.1 0.19 11.6 0.0 4.0 3 0 0 3 3 3 1 RsgA GTPase AAA_30 PF13604.6 EGF78087.1 - 0.00029 20.6 1.4 1 9.0 0.1 4.4 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 EGF78087.1 - 0.0014 17.9 0.2 1.8 7.8 0.0 4.0 4 0 0 4 4 4 1 Zeta toxin ABC_tran PF00005.27 EGF78087.1 - 0.0084 16.6 5.6 21 5.6 0.1 5.1 6 0 0 6 6 3 0 ABC transporter DUF815 PF05673.13 EGF78087.1 - 0.012 14.8 0.0 4.8 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGF78087.1 - 0.019 15.1 0.1 9 6.4 0.1 3.6 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EGF78087.1 - 0.047 13.8 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EGF78087.1 - 0.068 13.4 1.2 24 5.1 0.0 3.8 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 EGF78087.1 - 0.069 13.1 0.3 29 4.5 0.0 4.0 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.9 EGF78087.1 - 0.08 11.8 0.5 7.2 5.4 0.0 3.4 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 EGF78087.1 - 0.091 12.1 1.0 14 5.0 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EGF78087.1 - 0.097 12.4 11.3 0.64 9.8 0.1 5.1 6 0 0 6 6 5 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGF78087.1 - 0.12 11.9 0.2 12 5.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EGF78087.1 - 0.24 11.3 1.9 62 3.4 0.0 4.1 4 0 0 4 4 3 0 Rad17 P-loop domain AAA_19 PF13245.6 EGF78087.1 - 0.35 11.2 3.2 49 4.2 0.0 4.5 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 EGF78087.1 - 0.86 9.8 5.8 1.4 9.1 0.3 3.5 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase ArnB_C PF18677.1 EGF78088.1 - 0.22 11.7 1.7 0.58 10.3 0.6 2.3 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain IQ PF00612.27 EGF78088.1 - 3.6 7.6 5.3 21 5.3 0.2 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ras PF00071.22 EGF78089.1 - 3.2e-65 218.7 0.9 3.9e-65 218.4 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF78089.1 - 2.3e-36 124.7 0.1 4.3e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF78089.1 - 2.1e-17 63.1 0.1 2.7e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGF78089.1 - 4.9e-06 26.6 0.5 0.074 13.0 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGF78089.1 - 1.6e-05 24.4 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGF78089.1 - 3.4e-05 23.3 0.1 4.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGF78089.1 - 4.4e-05 23.5 0.1 7.1e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF78089.1 - 0.00011 21.9 0.3 0.0003 20.4 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EGF78089.1 - 0.0097 16.3 0.1 0.37 11.2 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF78089.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EGF78089.1 - 0.018 14.5 0.0 0.088 12.3 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EGF78089.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGF78089.1 - 0.062 13.1 0.1 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGF78089.1 - 0.065 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EGF78089.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 EGF78089.1 - 0.078 12.2 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 EGF78089.1 - 0.096 13.2 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EGF78089.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Cyclin_N PF00134.23 EGF78090.1 - 1.5e-37 128.2 0.4 1.5e-37 128.2 0.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF78090.1 - 1.1e-10 41.7 0.1 1.1e-10 41.7 0.1 4.1 4 1 1 5 5 5 1 Cyclin, C-terminal domain VWA PF00092.28 EGF78091.1 - 0.005 17.1 0.7 0.21 11.8 0.2 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain IMS PF00817.20 EGF78092.1 - 2.6e-42 144.3 0.0 7.8e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EGF78092.1 - 7.7e-08 33.1 0.0 7.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EGF78092.1 - 2e-05 24.1 2.6 3.1e-05 23.5 0.7 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EGF78092.1 - 0.00064 19.9 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-ribbon_3 PF13248.6 EGF78092.1 - 0.16 11.5 0.1 0.16 11.5 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Bombolitin PF08096.11 EGF78092.1 - 0.28 11.5 1.2 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Bombolitin family DUF4171 PF13775.6 EGF78092.1 - 0.69 10.4 8.0 5.7 7.4 8.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4171) UCH PF00443.29 EGF78093.1 - 5.6e-48 163.7 0.0 8.6e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF78093.1 - 4e-09 36.5 0.4 2.3e-05 24.1 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GCP_N_terminal PF17681.1 EGF78094.1 - 9e-40 137.2 0.1 1.6e-39 136.3 0.1 1.5 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGF78094.1 - 4.5e-32 111.8 0.3 7e-30 104.5 0.0 3.0 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Sec6 PF06046.13 EGF78094.1 - 0.12 10.7 1.1 8.6 4.6 0.2 2.7 2 1 0 3 3 3 0 Exocyst complex component Sec6 Ribosomal_L27e PF01777.18 EGF78095.1 - 1e-36 125.1 3.2 1.6e-36 124.5 3.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGF78095.1 - 2.2e-06 27.4 0.3 4.6e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 KOW motif Ras PF00071.22 EGF78096.1 - 3.3e-47 160.1 0.1 4.2e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF78096.1 - 7.3e-21 74.6 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF78096.1 - 5.4e-11 42.3 0.1 6.5e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF78096.1 - 0.00099 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGF78096.1 - 0.076 12.4 0.1 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Na_H_Exchanger PF00999.21 EGF78097.1 - 6e-57 193.2 30.0 8e-57 192.8 30.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EMC3_TMCO1 PF01956.16 EGF78097.1 - 0.4 10.4 7.2 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like YwcE PF17368.2 EGF78097.1 - 1.3 9.7 7.1 0.37 11.5 2.3 2.6 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE Mito_carr PF00153.27 EGF78098.1 - 4.5e-28 97.0 10.0 1.6e-16 60.0 0.2 3.8 3 2 0 3 3 3 3 Mitochondrial carrier protein 7tm_3 PF00003.22 EGF78099.1 - 7.2e-19 68.5 23.9 1.3e-18 67.7 23.9 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 EGF78099.1 - 5.5e-09 35.6 0.0 1.3e-05 24.5 0.0 2.4 1 1 1 2 2 2 2 Receptor family ligand binding region DUF4709 PF15821.5 EGF78101.1 - 1e-06 29.0 0.4 1e-06 29.0 0.4 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4709) Focal_AT PF03623.13 EGF78101.1 - 0.047 13.7 0.2 0.047 13.7 0.2 3.0 3 0 0 3 3 3 0 Focal adhesion targeting region GP57 PF17594.2 EGF78101.1 - 0.069 12.9 0.1 3.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Phage Tail fiber assembly helper gene product 57 PRESAN PF09687.10 EGF78101.1 - 0.13 12.8 5.3 0.063 13.8 1.5 2.4 2 0 0 2 2 2 0 Plasmodium RESA N-terminal DUF4482 PF14818.6 EGF78101.1 - 0.4 11.5 11.7 0.12 13.3 2.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) HR1 PF02185.16 EGF78101.1 - 3.4 7.8 8.7 0.27 11.4 2.2 2.7 2 1 1 3 3 3 0 Hr1 repeat AATF-Che1 PF13339.6 EGF78101.1 - 5.4 7.7 13.6 1.4 9.6 2.3 3.4 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor DUF2340 PF10209.9 EGF78102.1 - 1e-44 151.8 0.9 1.2e-44 151.6 0.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF5517 PF17639.2 EGF78102.1 - 0.0087 16.3 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5517) Aminotran_1_2 PF00155.21 EGF78104.1 - 1.1e-63 215.6 0.0 1.3e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGF78104.1 - 2.2e-06 26.5 0.1 4.9e-06 25.3 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGF78104.1 - 2.4e-06 27.1 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGF78104.1 - 6.3e-05 22.1 0.2 0.00029 19.9 0.1 2.0 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGF78104.1 - 0.00084 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase TPR_2 PF07719.17 EGF78105.1 - 1.3e-39 131.1 11.4 2.6e-05 24.0 0.1 12.4 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGF78105.1 - 1.1e-35 120.0 30.5 1.6e-05 24.5 0.2 12.7 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_12 PF13424.6 EGF78105.1 - 9.3e-33 112.4 13.6 2.8e-08 33.9 0.2 9.4 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGF78105.1 - 6.5e-27 93.8 3.2 1.3e-05 25.6 0.0 7.8 4 2 5 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGF78105.1 - 7.5e-25 85.0 20.2 0.00033 20.6 0.2 12.1 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGF78105.1 - 2e-24 84.6 13.5 0.00047 20.6 0.0 12.1 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78105.1 - 4.9e-23 79.9 0.0 0.0012 19.5 0.0 10.4 6 3 6 12 12 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF78105.1 - 1.3e-20 72.8 8.8 3.7e-05 23.3 0.1 9.7 7 1 3 10 10 10 4 TPR repeat TPR_16 PF13432.6 EGF78105.1 - 1.9e-20 73.2 0.0 0.00074 20.1 0.0 7.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78105.1 - 2.9e-20 70.7 18.0 0.014 15.3 0.0 11.3 11 1 1 12 12 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF78105.1 - 2e-13 50.4 15.1 0.00052 20.2 0.0 7.1 4 3 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGF78105.1 - 7.5e-12 44.7 18.2 0.00038 20.2 0.2 9.4 11 0 0 11 11 9 2 Tetratricopeptide repeat RPN7 PF10602.9 EGF78105.1 - 2.1e-09 37.3 3.0 0.028 14.1 0.0 6.4 3 3 3 6 6 6 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 EGF78105.1 - 3.5e-09 36.7 0.0 0.2 11.8 0.0 5.3 5 2 2 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF78105.1 - 6.7e-08 32.4 12.3 1.8 9.1 0.6 9.2 9 1 0 9 9 8 1 Tetratricopeptide repeat NARP1 PF12569.8 EGF78105.1 - 9.4e-08 31.4 4.7 0.24 10.3 0.0 5.6 3 1 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 EGF78105.1 - 1.7e-07 31.2 5.8 3.7e-05 23.5 0.6 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EGF78105.1 - 1.8e-07 30.8 0.1 0.2 11.0 0.0 4.7 4 1 1 5 5 5 2 MalT-like TPR region Fis1_TPR_C PF14853.6 EGF78105.1 - 3.6e-07 30.1 2.5 1.6 8.9 0.0 6.6 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 EGF78105.1 - 7.4e-06 26.2 4.1 0.26 11.7 0.0 6.5 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGF78105.1 - 1.7e-05 24.2 3.4 0.0012 18.1 0.1 3.8 5 1 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 EGF78105.1 - 0.00017 22.1 0.0 1.2 9.5 0.1 3.9 3 1 0 3 3 3 1 Bacterial transcriptional activator domain DUF3808 PF10300.9 EGF78105.1 - 0.00032 19.6 1.8 0.019 13.7 0.0 3.1 2 2 1 3 3 3 1 Protein of unknown function (DUF3808) PPR PF01535.20 EGF78105.1 - 0.0022 18.1 0.2 24 5.5 0.0 5.4 7 0 0 7 7 4 0 PPR repeat Sel1 PF08238.12 EGF78105.1 - 0.0037 17.9 11.1 0.13 13.0 0.9 5.7 6 1 0 6 6 4 1 Sel1 repeat DUF2225 PF09986.9 EGF78105.1 - 0.0039 16.9 14.9 0.0082 15.9 2.5 4.8 2 2 2 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) ATP13 PF12921.7 EGF78105.1 - 0.0054 16.6 1.6 16 5.4 0.0 5.0 5 1 0 5 5 5 0 Mitochondrial ATPase expression Wzy_C_2 PF11846.8 EGF78105.1 - 0.0056 16.6 0.3 12 5.8 0.0 3.8 3 1 2 5 5 4 0 Virulence factor membrane-bound polymerase, C-terminal YfiO PF13525.6 EGF78105.1 - 0.0068 16.2 6.8 4.4 7.0 0.2 4.5 3 2 3 6 6 6 1 Outer membrane lipoprotein HemY_N PF07219.13 EGF78105.1 - 0.028 14.6 3.6 14 6.0 0.0 3.9 3 1 1 4 4 4 0 HemY protein N-terminus LUC7 PF03194.15 EGF78105.1 - 0.043 13.5 2.4 0.14 11.8 0.6 2.3 2 0 0 2 2 2 0 LUC7 N_terminus TPR_5 PF12688.7 EGF78105.1 - 0.083 13.1 0.0 0.71 10.1 0.0 2.6 3 0 0 3 3 1 0 Tetratrico peptide repeat DUF627 PF04781.12 EGF78105.1 - 0.088 12.8 0.2 11 6.1 0.1 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF627) Foie-gras_1 PF11817.8 EGF78105.1 - 0.17 11.4 3.7 20 4.7 0.0 4.3 4 1 1 5 5 5 0 Foie gras liver health family 1 TPR_3 PF07720.12 EGF78105.1 - 1.9 8.5 22.1 4.1 7.5 0.3 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat SPO22 PF08631.10 EGF78105.1 - 2.2 7.7 6.8 11 5.4 0.1 4.4 4 2 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 EGF78105.1 - 2.8 8.1 18.6 80 3.4 0.0 7.8 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain tRNA-synt_2b PF00587.25 EGF78106.1 - 7.4e-36 123.8 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGF78106.1 - 2.8e-19 69.3 7.6 5.8e-19 68.3 7.6 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 EGF78106.1 - 0.13 12.5 2.5 0.24 11.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) eIF2A PF08662.11 EGF78107.1 - 4e-52 176.9 12.1 5.7e-47 160.1 3.5 4.2 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGF78107.1 - 4.7e-05 21.6 0.5 0.00014 20.1 0.2 1.8 1 1 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGF78107.1 - 0.00038 20.7 3.1 1.7 9.0 0.0 5.9 4 1 4 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EGF78107.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGF78107.1 - 0.0025 18.6 6.9 2.8 8.9 0.0 5.7 6 1 1 7 7 7 1 WD domain, G-beta repeat TFIIIC_delta PF12657.7 EGF78107.1 - 0.068 13.1 5.5 0.11 12.4 0.0 3.3 4 0 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Radial_spoke PF04712.12 EGF78108.1 - 4.8e-152 507.3 0.0 6.4e-152 506.9 0.0 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein AMP-binding PF00501.28 EGF78111.1 - 1.2e-83 281.1 0.0 1.5e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF78111.1 - 1.9e-17 64.0 0.7 1.9e-17 64.0 0.7 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EGF78111.1 - 0.01 14.7 0.0 0.044 12.6 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hpr_kinase_N PF02603.16 EGF78111.1 - 0.13 12.2 0.1 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 HPr Serine kinase N terminus Tub PF01167.18 EGF78112.1 - 4.2e-60 203.5 0.2 1e-59 202.3 0.0 1.7 2 0 0 2 2 2 1 Tub family Drc1-Sld2 PF11719.8 EGF78112.1 - 8.1e-13 48.7 5.5 8.1e-13 48.7 5.5 2.5 2 1 1 3 3 3 1 DNA replication and checkpoint protein Metallophos PF00149.28 EGF78113.1 - 4.2e-07 30.7 0.4 4.2e-07 30.7 0.4 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Symplekin_C PF12295.8 EGF78114.1 - 2.2e-54 184.4 0.4 2.2e-54 184.4 0.4 2.8 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EGF78114.1 - 5.2e-41 140.7 0.7 5.2e-41 140.7 0.7 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) Glyco_transf_20 PF00982.21 EGF78115.1 - 2.5e-163 544.1 0.3 3.5e-163 543.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGF78115.1 - 5.8e-47 159.8 0.0 1.5e-40 138.8 0.0 2.7 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGF78115.1 - 7.2e-06 25.9 0.0 0.34 10.6 0.0 3.4 3 1 0 4 4 4 2 haloacid dehalogenase-like hydrolase Ribonuc_red_sm PF00268.21 EGF78116.1 - 7.4e-64 215.9 0.5 9.5e-64 215.5 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Methyltransf_23 PF13489.6 EGF78117.1 - 2.3e-19 69.8 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF78117.1 - 9.2e-09 35.9 0.0 4e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF78117.1 - 1.7e-07 31.8 0.0 3.2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF78117.1 - 6.3e-07 30.1 0.0 1.7e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF78117.1 - 0.00078 18.8 0.0 0.0018 17.7 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGF78117.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.16 EGF78117.1 - 0.016 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme KH_1 PF00013.29 EGF78118.1 - 1.1e-44 150.1 11.6 6.5e-18 64.3 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGF78118.1 - 9.7e-17 60.6 5.2 6.5e-05 22.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGF78118.1 - 5.3e-14 51.8 6.7 0.00019 21.2 0.4 3.5 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EGF78118.1 - 2.1e-05 24.4 0.0 0.087 12.8 0.0 3.1 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 EGF78118.1 - 0.017 15.2 8.1 7.4 6.7 0.1 3.8 4 0 0 4 4 4 0 NusA-like KH domain HAUS4 PF14735.6 EGF78119.1 - 0.00065 19.5 4.7 0.0033 17.2 0.4 2.9 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 4 HBM PF16591.5 EGF78119.1 - 0.031 13.7 0.4 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Helical bimodular sensor domain BLOC1_2 PF10046.9 EGF78119.1 - 0.065 13.5 3.4 5.9 7.3 0.1 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RasGEF_N_2 PF14663.6 EGF78119.1 - 0.091 13.2 0.4 14 6.2 0.0 2.6 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Baculo_PEP_C PF04513.12 EGF78119.1 - 0.12 12.4 6.5 3 7.9 1.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 EGF78119.1 - 0.13 12.7 1.2 17 5.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) FadA PF09403.10 EGF78119.1 - 0.34 11.4 2.2 0.7 10.4 0.2 2.5 3 0 0 3 3 3 0 Adhesion protein FadA COX6B PF02297.17 EGF78120.1 - 0.0027 17.9 0.4 0.0041 17.3 0.4 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.13 EGF78120.1 - 0.0039 17.5 0.3 0.067 13.6 0.1 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 EGF78120.1 - 0.0094 15.9 0.3 0.074 13.1 0.0 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EGF78120.1 - 0.01 15.9 3.5 0.15 12.2 3.2 2.1 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.8 EGF78120.1 - 0.05 14.0 0.2 6.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Cmc1 PF08583.10 EGF78120.1 - 0.61 10.2 3.8 9.3 6.4 3.8 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DEAD PF00270.29 EGF78121.1 - 3e-44 150.9 0.4 5.9e-44 149.9 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF78121.1 - 6.4e-33 113.4 0.4 9.6e-32 109.6 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF78121.1 - 3.2e-07 30.5 0.0 5.2e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGF78121.1 - 0.00029 21.2 1.0 0.0057 17.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGF78121.1 - 0.00078 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF78121.1 - 0.01 16.1 0.2 0.033 14.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 EGF78121.1 - 0.013 15.4 0.1 0.13 12.2 0.0 2.4 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EGF78121.1 - 0.023 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 EGF78121.1 - 0.044 13.1 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TniB PF05621.11 EGF78121.1 - 0.086 12.2 0.1 0.23 10.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial TniB protein WD40 PF00400.32 EGF78122.1 - 3.6e-30 103.6 14.1 5.1e-07 30.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78122.1 - 1.4e-25 89.4 0.2 2.4e-06 27.8 0.0 6.4 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF78122.1 - 2.2e-11 44.0 0.0 4.5e-06 26.7 0.0 3.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGF78122.1 - 0.00025 20.5 0.0 1.6 8.0 0.0 3.4 3 1 1 4 4 4 2 WD40-like domain IKI3 PF04762.12 EGF78122.1 - 0.0051 14.9 0.0 0.26 9.2 0.0 2.8 2 1 1 3 3 3 2 IKI3 family Cytochrom_D1 PF02239.16 EGF78122.1 - 0.043 12.4 0.0 0.41 9.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain FeThRed_A PF02941.15 EGF78122.1 - 0.045 13.9 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain Atg29_N PF18388.1 EGF78122.1 - 0.086 12.7 0.2 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Atg29 N-terminal domain MitMem_reg PF13012.6 EGF78123.1 - 8.4e-36 122.8 1.1 1.8e-35 121.8 1.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGF78123.1 - 7.9e-33 112.9 0.1 2e-32 111.6 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease EnY2 PF10163.9 EGF78124.1 - 1.9e-29 101.9 0.6 2.1e-29 101.7 0.6 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Phg_2220_C PF09524.10 EGF78124.1 - 0.041 13.9 0.5 0.2 11.8 0.1 2.1 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) V-SNARE PF05008.15 EGF78124.1 - 0.11 12.9 0.4 0.24 11.8 0.1 1.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF668 PF05003.12 EGF78124.1 - 0.13 12.7 0.3 3.7 8.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF668) COX6B PF02297.17 EGF78125.1 - 0.0027 17.9 0.4 0.0041 17.3 0.4 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.13 EGF78125.1 - 0.0039 17.5 0.3 0.067 13.6 0.1 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 EGF78125.1 - 0.0094 15.9 0.3 0.074 13.1 0.0 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EGF78125.1 - 0.01 15.9 3.5 0.15 12.2 3.2 2.1 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.8 EGF78125.1 - 0.05 14.0 0.2 6.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Cmc1 PF08583.10 EGF78125.1 - 0.61 10.2 3.8 9.3 6.4 3.8 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like JHY PF15261.6 EGF78126.1 - 2.2 9.0 6.1 0.56 10.9 1.8 2.2 1 1 1 2 2 2 0 Jhy protein TIP49 PF06068.13 EGF78130.1 - 5.9e-159 528.9 1.5 5.9e-159 528.9 1.5 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EGF78130.1 - 7.5e-28 96.5 1.1 7.5e-28 96.5 1.1 2.2 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGF78130.1 - 1.8e-08 34.9 3.3 1.5e-05 25.4 0.1 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGF78130.1 - 4.7e-08 32.9 0.8 0.00044 20.0 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGF78130.1 - 9e-06 25.7 0.2 0.0053 16.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 EGF78130.1 - 1.1e-05 24.9 0.4 2.2e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EGF78130.1 - 1.9e-05 24.2 1.5 0.00076 18.9 0.6 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGF78130.1 - 9.7e-05 22.8 0.1 0.00044 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF78130.1 - 0.00078 19.7 0.0 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGF78130.1 - 0.0017 18.0 0.0 0.014 14.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGF78130.1 - 0.0033 17.8 6.1 0.029 14.7 2.6 3.0 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGF78130.1 - 0.004 16.9 0.4 1.8 8.2 0.1 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 EGF78130.1 - 0.0046 17.4 0.4 0.013 16.0 0.4 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGF78130.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGF78130.1 - 0.015 14.6 1.7 0.042 13.2 1.7 1.7 1 1 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 EGF78130.1 - 0.023 14.0 0.4 0.054 12.8 0.4 1.6 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 EGF78130.1 - 0.036 13.2 0.5 6.5 5.8 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_28 PF13521.6 EGF78130.1 - 0.064 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGF78130.1 - 0.099 12.6 0.9 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGF78130.1 - 0.21 11.1 2.6 0.37 10.3 0.0 2.6 4 0 0 4 4 4 0 P-loop containing dynein motor region ResIII PF04851.15 EGF78130.1 - 0.76 9.8 4.1 3.1 7.8 1.5 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit FPL PF09758.9 EGF78131.1 - 2.2e-18 66.7 8.1 1.5e-12 47.8 1.1 2.9 2 1 1 3 3 3 2 Uncharacterised conserved protein WD-3 PF09765.9 EGF78132.1 - 1.7e-32 112.9 0.0 2.3e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 EGF78132.1 - 1.2e-19 70.3 3.1 2e-19 69.6 2.1 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EGF78132.1 - 4.8e-07 30.0 5.6 1.3e-06 28.7 5.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGF78132.1 - 9.2e-05 22.7 3.8 0.0002 21.6 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 EGF78132.1 - 0.0051 17.1 0.3 0.019 15.3 0.3 1.9 1 0 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 EGF78132.1 - 0.069 13.0 2.2 0.2 11.6 2.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGF78132.1 - 0.089 12.9 2.7 0.26 11.4 2.7 1.9 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 EGF78132.1 - 0.1 12.7 4.0 0.32 11.1 4.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EGF78132.1 - 0.31 11.0 2.8 0.91 9.5 2.8 1.9 1 0 0 1 1 1 0 PHD-finger Dpy-30 PF05186.13 EGF78133.1 - 1.6e-15 56.5 0.1 2.9e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 EGF78133.1 - 4.6e-14 52.8 0.4 9.7e-12 45.2 0.4 2.8 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGF78133.1 - 6.1e-09 36.4 7.4 7.3e-06 26.5 0.1 3.9 3 1 1 4 4 3 2 AAA domain Hydin_ADK PF17213.3 EGF78133.1 - 2.8e-07 31.0 0.0 2.8e-07 31.0 0.0 3.4 3 1 1 4 4 3 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 EGF78133.1 - 4.8e-07 30.4 0.3 4.5e-06 27.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF78133.1 - 0.00018 21.7 0.2 0.00084 19.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 EGF78133.1 - 0.00052 20.2 0.1 0.0019 18.3 0.1 2.0 1 0 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 EGF78133.1 - 0.00064 19.7 0.1 0.012 15.5 0.0 2.7 2 1 1 3 3 3 1 NTPase AAA_16 PF13191.6 EGF78133.1 - 0.00072 20.0 0.0 0.003 18.0 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_28 PF13521.6 EGF78133.1 - 0.001 19.3 0.0 0.001 19.3 0.0 2.7 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 EGF78133.1 - 0.0013 19.1 0.1 0.011 16.1 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGF78133.1 - 0.003 17.9 0.0 0.36 11.2 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGF78133.1 - 0.005 16.9 0.6 0.09 12.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGF78133.1 - 0.0099 16.2 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGF78133.1 - 0.011 15.2 0.1 0.066 12.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 EGF78133.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Serine_rich PF08824.10 EGF78133.1 - 0.023 14.7 0.1 0.081 12.9 0.1 1.9 1 0 0 1 1 1 0 Serine rich protein interaction domain AAA_11 PF13086.6 EGF78133.1 - 0.037 13.8 2.5 2.9 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGF78133.1 - 0.041 13.8 0.0 0.041 13.8 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGF78133.1 - 0.096 13.2 0.6 1.3 9.5 0.1 2.8 2 1 0 2 2 2 0 ABC transporter Vps54 PF07928.12 EGF78134.1 - 1.2e-51 174.7 0.7 5.5e-51 172.5 0.2 2.5 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EGF78134.1 - 9.8e-07 28.3 0.1 9.8e-07 28.3 0.1 2.3 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGF78134.1 - 6.4e-06 26.1 0.2 2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 EGF78134.1 - 0.0079 15.1 0.1 0.12 11.2 0.1 2.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family COG2 PF06148.11 EGF78134.1 - 1.5 8.9 5.4 1.6 8.8 1.3 2.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NuA4 PF09340.10 EGF78135.1 - 5.8e-20 71.0 0.3 7.6e-20 70.6 0.3 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 B56 PF01603.20 EGF78136.1 - 1.1e-194 647.2 10.0 1.4e-194 646.9 10.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) APOBEC2 PF18772.1 EGF78136.1 - 0.089 12.8 0.2 6.7 6.7 0.0 2.3 2 0 0 2 2 2 0 APOBEC2 NAD1 PF18778.1 EGF78136.1 - 0.12 12.5 0.7 6 6.9 1.2 2.2 1 1 1 2 2 2 0 Novel AID APOBEC clade 1 Ribonucleas_3_3 PF14622.6 EGF78137.1 - 8.8e-18 64.7 0.1 1.3e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGF78137.1 - 3.2e-08 34.2 0.0 6.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EGF78137.1 - 1.3e-05 25.8 0.0 2.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif EF-hand_4 PF12763.7 EGF78138.1 - 2e-25 88.7 0.0 2.7e-09 36.9 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EGF78138.1 - 1.5e-09 38.1 0.0 8.1e-07 29.4 0.1 3.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EGF78138.1 - 3.7e-07 29.2 0.0 0.76 9.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGF78138.1 - 1e-06 28.2 0.2 0.15 12.1 0.4 4.4 4 0 0 4 4 4 2 EF-hand domain SHE3 PF17078.5 EGF78138.1 - 3.3 7.4 30.4 4.1 7.1 28.9 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 EGF78138.1 - 8.8 6.7 38.3 5.3e+02 0.9 37.1 2.4 1 1 0 1 1 1 0 Fez1 Ndc1_Nup PF09531.10 EGF78139.1 - 5.4e-46 157.5 25.2 2.6e-45 155.3 25.2 1.8 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 EGF78140.1 - 2e-15 56.3 0.0 3.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPS2_interact PF15784.5 EGF78140.1 - 0.016 15.6 3.4 0.025 15.0 3.4 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Nup35_RRM_2 PF14605.6 EGF78140.1 - 0.021 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif KASH_CCD PF14662.6 EGF78140.1 - 0.067 13.0 6.3 0.096 12.5 6.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3584 PF12128.8 EGF78140.1 - 0.092 10.3 2.0 0.11 10.0 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lge1 PF11488.8 EGF78140.1 - 0.17 12.1 1.7 5.2 7.3 2.3 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 XhlA PF10779.9 EGF78140.1 - 0.29 11.4 3.0 0.45 10.8 3.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA GBP_C PF02841.14 EGF78140.1 - 1.8 7.9 8.5 2.5 7.4 8.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Pro_CA PF00484.19 EGF78141.1 - 1.4e-47 161.9 0.0 2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase ComX PF05952.12 EGF78141.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX OST3_OST6 PF04756.13 EGF78142.1 - 9.1e-86 287.8 4.4 1e-85 287.7 4.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family BTB_3 PF16017.5 EGF78143.1 - 0.019 15.0 0.1 0.041 14.0 0.1 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF78143.1 - 0.037 14.4 0.5 0.037 14.4 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3888) DUF4796 PF16044.5 EGF78144.1 - 0.086 12.4 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf-RING_7 PF02591.15 EGF78144.1 - 0.2 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 C4-type zinc ribbon domain Auxin_canalis PF05703.11 EGF78145.1 - 0.49 10.3 3.1 0.78 9.6 3.1 1.2 1 0 0 1 1 1 0 Auxin canalisation DDE_Tnp_1 PF01609.21 EGF78145.1 - 0.97 9.0 9.6 1.8 8.2 9.6 1.4 1 0 0 1 1 1 0 Transposase DDE domain Plus-3 PF03126.18 EGF78147.1 - 0.019 15.5 0.2 0.75 10.3 0.0 2.9 3 0 0 3 3 3 0 Plus-3 domain AFG1_ATPase PF03969.16 EGF78147.1 - 0.031 13.2 0.1 0.075 11.9 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 EGF78147.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_22 PF13401.6 EGF78147.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGF78147.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain HpaP PF09483.10 EGF78147.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Phage_Gp19 PF09355.10 EGF78147.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 TPX2_importin PF12214.8 EGF78149.1 - 1.6e-11 44.7 40.3 6.2e-10 39.5 8.6 6.2 3 2 2 5 5 5 4 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 EGF78149.1 - 1.2e-10 41.4 10.8 1.2e-10 41.4 10.8 4.5 4 0 0 4 4 4 2 Targeting protein for Xklp2 (TPX2) Aurora-A_bind PF09041.10 EGF78149.1 - 7.3 6.7 7.4 5.9 7.0 3.9 2.6 2 0 0 2 2 2 0 Aurora-A binding TEX13 PF15186.6 EGF78149.1 - 9.6 5.9 9.2 4.1 7.1 5.5 2.3 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family NAC PF01849.18 EGF78150.1 - 4.2e-21 74.7 0.0 1.5e-19 69.7 0.0 2.4 2 0 0 2 2 2 1 NAC domain MqsR_toxin PF15723.5 EGF78150.1 - 0.13 12.7 0.3 13 6.2 0.0 2.7 2 1 1 3 3 3 0 Motility quorum-sensing regulator, toxin of MqsA PhoLip_ATPase_C PF16212.5 EGF78151.1 - 4.5e-47 160.9 21.2 4.5e-47 160.9 21.2 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGF78151.1 - 2.4e-14 54.2 0.1 3.5e-11 43.8 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 EGF78151.1 - 2.5e-13 49.5 7.6 6.9e-13 48.1 7.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGF78151.1 - 2.4e-10 40.3 0.4 5e-09 35.9 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGF78151.1 - 3.5e-07 30.2 0.0 5.9e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGF78151.1 - 0.0026 17.6 0.1 0.0065 16.2 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dynamin_M PF01031.20 EGF78152.1 - 3.9e-100 334.7 0.0 7e-100 333.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGF78152.1 - 2.2e-57 193.8 0.1 4.8e-57 192.7 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGF78152.1 - 7.5e-29 99.7 5.1 2e-28 98.4 5.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGF78152.1 - 2.7e-05 24.2 0.9 0.00049 20.1 0.9 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Baculo_PEP_C PF04513.12 EGF78152.1 - 0.05 13.7 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FeoB_N PF02421.18 EGF78152.1 - 0.06 12.9 0.3 12 5.4 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B CN_hydrolase PF00795.22 EGF78153.1 - 2.1e-38 132.2 0.0 2.8e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGF78153.1 - 5e-23 81.5 0.0 2.7e-22 79.1 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Pkinase PF00069.25 EGF78154.1 - 4.3e-67 226.3 0.0 5.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78154.1 - 1.6e-50 171.8 0.0 2.1e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78154.1 - 0.0013 18.1 0.2 0.0036 16.7 0.2 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF78154.1 - 0.0043 15.9 0.0 0.0068 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LSM PF01423.22 EGF78155.1 - 1.3e-16 60.0 0.1 1.8e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGF78155.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Hfq protein AAA PF00004.29 EGF78157.1 - 4.2e-97 321.6 0.0 3.5e-49 166.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF78157.1 - 1.6e-20 72.6 0.0 3.9e-09 36.2 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGF78157.1 - 2.6e-14 53.3 0.0 2.9e-06 27.1 0.0 3.0 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGF78157.1 - 1.7e-13 51.3 0.6 0.0017 18.8 0.0 4.5 2 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 EGF78157.1 - 8.1e-12 45.6 0.0 0.00017 21.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGF78157.1 - 2.4e-11 44.1 0.6 0.0019 18.5 0.0 4.6 2 2 1 4 4 4 2 AAA domain AAA_5 PF07728.14 EGF78157.1 - 3e-11 43.5 1.5 0.00053 20.0 0.3 4.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGF78157.1 - 8.2e-10 39.0 0.0 0.00056 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGF78157.1 - 1e-08 35.3 0.7 0.009 15.9 0.0 4.3 4 1 1 5 5 4 2 NACHT domain TIP49 PF06068.13 EGF78157.1 - 2.7e-08 33.4 1.0 0.0015 17.8 0.2 2.8 2 1 1 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 EGF78157.1 - 3.5e-08 33.1 0.7 0.0086 15.5 0.2 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGF78157.1 - 4.9e-08 33.1 0.0 0.0085 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGF78157.1 - 1.7e-07 31.6 0.0 0.0073 16.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EGF78157.1 - 3.8e-07 30.5 0.0 0.011 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGF78157.1 - 4.1e-07 30.6 0.0 0.048 14.2 0.0 2.9 2 1 1 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EGF78157.1 - 4.4e-07 29.8 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 EGF78157.1 - 6.4e-07 29.1 0.8 0.83 9.2 0.0 4.2 3 1 1 4 4 4 2 AAA domain TsaE PF02367.17 EGF78157.1 - 7.9e-07 29.1 0.0 0.046 13.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGF78157.1 - 1.3e-06 29.0 0.0 0.13 12.8 0.0 2.8 2 1 1 3 3 3 2 ABC transporter Viral_helicase1 PF01443.18 EGF78157.1 - 3.6e-06 26.9 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EGF78157.1 - 5.3e-06 26.0 0.1 0.19 11.0 0.0 3.4 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 EGF78157.1 - 9e-06 25.5 0.0 0.13 11.9 0.0 3.6 3 1 0 3 3 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EGF78157.1 - 9.9e-06 25.6 0.0 0.15 12.0 0.0 3.5 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EGF78157.1 - 1e-05 25.4 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGF78157.1 - 1.1e-05 25.5 0.0 0.085 12.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 EGF78157.1 - 1.3e-05 24.8 0.0 0.044 13.3 0.0 3.4 2 2 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 EGF78157.1 - 1.3e-05 25.6 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EGF78157.1 - 1.8e-05 24.0 0.1 0.13 11.4 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain Zeta_toxin PF06414.12 EGF78157.1 - 8.6e-05 21.9 0.1 0.42 9.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Cytidylate_kin2 PF13189.6 EGF78157.1 - 0.00011 22.4 0.0 0.066 13.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_24 PF13479.6 EGF78157.1 - 0.00018 21.3 0.0 0.29 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 EGF78157.1 - 0.00037 20.6 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 EGF78157.1 - 0.00037 19.7 0.0 0.1 11.8 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EGF78157.1 - 0.00063 19.6 0.0 0.89 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 EGF78157.1 - 0.00069 19.8 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Parvo_NS1 PF01057.17 EGF78157.1 - 0.0007 18.8 0.0 0.93 8.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 TniB PF05621.11 EGF78157.1 - 0.001 18.5 0.0 5.1 6.4 0.0 3.7 3 1 0 3 3 3 0 Bacterial TniB protein ATP-synt_ab PF00006.25 EGF78157.1 - 0.0019 17.9 0.0 0.79 9.3 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.16 EGF78157.1 - 0.0026 17.2 0.3 1.2 8.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein PduV-EutP PF10662.9 EGF78157.1 - 0.0051 16.6 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.18 EGF78157.1 - 0.0067 16.3 0.1 3.3 7.5 0.0 3.4 3 1 0 3 3 3 1 Bacterial dnaA protein Vps4_C PF09336.10 EGF78157.1 - 0.01 15.8 0.3 0.32 11.0 0.0 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain CPT PF07931.12 EGF78157.1 - 0.013 15.4 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 EGF78157.1 - 0.016 15.6 0.9 5.8 7.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGF78157.1 - 0.038 13.7 0.1 9.7 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGF78157.1 - 0.078 12.9 0.1 16 5.3 0.0 3.0 2 1 1 3 3 2 0 NTPase AAA_23 PF13476.6 EGF78157.1 - 0.11 13.0 0.0 5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EGF78157.1 - 0.13 11.7 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Zot PF05707.12 EGF78157.1 - 0.13 11.8 0.1 8 6.0 0.0 3.3 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) DUF2075 PF09848.9 EGF78157.1 - 0.15 11.3 0.2 14 4.8 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 EGF78157.1 - 0.15 11.8 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase ADK PF00406.22 EGF78157.1 - 0.16 12.1 0.0 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase Ras PF00071.22 EGF78158.1 - 7.8e-36 123.1 0.0 1.1e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF78158.1 - 7.4e-33 113.3 0.0 1e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF78158.1 - 9.4e-10 38.2 0.0 1.7e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF78158.1 - 1.2e-07 31.5 0.0 5.8e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF78158.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF78158.1 - 0.00017 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EGF78158.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MCM PF00493.23 EGF78158.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain MIR PF02815.19 EGF78159.1 - 2.1e-11 44.0 0.0 3.1e-10 40.2 0.0 2.3 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 EGF78159.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor LSM PF01423.22 EGF78160.1 - 1.9e-16 59.5 0.2 2.5e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGF78160.1 - 0.0033 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Hfq protein RRM_1 PF00076.22 EGF78161.1 - 1e-13 50.8 0.0 1.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGF78161.1 - 0.0034 17.3 0.2 0.0065 16.4 0.2 1.4 1 0 0 1 1 1 1 RL domain Nup35_RRM_2 PF14605.6 EGF78161.1 - 0.037 14.0 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGF78161.1 - 0.046 13.3 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF78161.1 - 0.095 12.8 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 RNA recognition motif COX4 PF02936.14 EGF78162.1 - 7.2e-26 90.8 0.2 9.4e-26 90.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SCA7 PF08313.12 EGF78163.1 - 2.1e-24 85.2 1.1 7.4e-24 83.4 0.1 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.11 EGF78163.1 - 0.0015 18.0 0.2 0.0033 17.0 0.2 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Dapper PF15268.6 EGF78163.1 - 0.42 9.4 12.9 0.059 12.2 8.5 1.6 1 1 0 1 1 1 0 Dapper DUF4674 PF15719.5 EGF78163.1 - 0.59 10.2 14.4 0.22 11.6 9.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4674) Ins_P5_2-kin PF06090.12 EGF78164.1 - 4e-27 95.5 0.0 4.5e-14 52.6 0.0 2.0 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase HTH_9 PF08221.11 EGF78165.1 - 7.9e-23 80.3 3.4 1.7e-16 60.1 0.1 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EGF78165.1 - 2e-05 24.4 8.8 0.002 17.9 1.0 3.8 4 0 0 4 4 4 2 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.13 EGF78165.1 - 0.0011 18.8 0.3 0.34 10.6 0.1 2.5 1 1 1 2 2 2 2 RNA polymerase III subunit RPC82 Rieske PF00355.26 EGF78166.1 - 1.5e-11 44.1 0.1 2.3e-11 43.5 0.1 1.3 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EGF78166.1 - 0.0033 17.8 0.3 0.0058 17.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF2516 PF10724.9 EGF78166.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) Alg6_Alg8 PF03155.15 EGF78167.1 - 1.8e-166 554.9 35.2 2e-166 554.7 35.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family MAT1 PF06391.13 EGF78168.1 - 1e-22 81.0 3.8 1.3e-22 80.7 3.8 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EGF78168.1 - 1.2e-21 76.4 8.9 1.2e-21 76.4 8.9 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF78168.1 - 9.6e-07 28.7 7.2 2.9e-06 27.1 7.4 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGF78168.1 - 1.5e-06 28.4 7.8 2.7e-06 27.6 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGF78168.1 - 2.4e-06 27.3 7.6 5.2e-06 26.2 7.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF78168.1 - 8.4e-06 25.6 7.3 2.2e-05 24.2 7.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF78168.1 - 1.2e-05 25.1 9.4 2.4e-05 24.1 9.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF78168.1 - 0.00014 21.6 11.0 0.00049 19.9 4.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF78168.1 - 0.00022 21.2 8.2 0.00026 20.9 4.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGF78168.1 - 0.0014 18.4 6.7 0.015 15.1 1.5 2.4 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain RNF220 PF15926.5 EGF78168.1 - 0.022 14.4 0.8 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_4 PF15227.6 EGF78168.1 - 0.074 13.2 8.3 0.43 10.8 8.6 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C2H2_9 PF16293.5 EGF78168.1 - 0.09 12.6 0.4 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-P11 PF03854.14 EGF78168.1 - 0.11 12.2 9.7 0.15 11.7 3.0 2.4 1 1 1 2 2 2 0 P-11 zinc finger GAGA PF09237.11 EGF78168.1 - 0.11 12.3 3.1 0.14 12.0 0.7 2.1 2 0 0 2 2 2 0 GAGA factor zf-rbx1 PF12678.7 EGF78168.1 - 0.16 12.3 5.7 0.38 11.1 5.7 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 EGF78168.1 - 0.59 10.0 4.4 2.1 8.3 0.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RRN7 PF11781.8 EGF78168.1 - 0.66 9.7 0.1 0.66 9.7 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_6 PF14835.6 EGF78168.1 - 1 9.3 5.5 4.6 7.2 5.5 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein TF_Zn_Ribbon PF08271.12 EGF78168.1 - 1.1 8.9 7.3 0.68 9.5 0.2 2.7 3 0 0 3 3 2 0 TFIIB zinc-binding Baculo_IE-1 PF05290.11 EGF78168.1 - 3 7.8 8.4 6.7 6.7 6.4 2.3 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF3797 PF12677.7 EGF78168.1 - 3.2 7.7 8.7 0.32 10.9 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) RecR PF02132.15 EGF78168.1 - 4.7 6.9 8.3 21 4.8 2.5 2.8 2 1 0 2 2 2 0 RecR protein G-patch_2 PF12656.7 EGF78169.1 - 7.4e-25 86.8 0.0 1.6e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 G-patch domain KN17_SH3 PF18131.1 EGF78169.1 - 3.9e-09 36.5 2.2 6.7e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 KN17 SH3-like C-terminal domain G-patch PF01585.23 EGF78169.1 - 8.9e-08 31.9 0.3 4.1e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 G-patch domain KOW PF00467.29 EGF78169.1 - 0.0024 17.8 2.2 0.26 11.3 2.9 3.1 2 1 0 2 2 2 1 KOW motif CI-B14_5a PF07347.12 EGF78170.1 - 0.002 18.0 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) MFS_2 PF13347.6 EGF78171.1 - 5.1e-11 41.8 8.6 5.1e-11 41.8 8.6 3.1 2 1 0 4 4 4 2 MFS/sugar transport protein BT1 PF03092.16 EGF78171.1 - 0.012 13.8 1.2 0.025 12.8 1.2 1.6 1 0 0 1 1 1 0 BT1 family Proteasome PF00227.26 EGF78172.1 - 6.8e-63 211.6 0.3 8.4e-63 211.3 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF78172.1 - 1.4e-13 50.2 0.1 3.1e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cpn60_TCP1 PF00118.24 EGF78173.1 - 4.8e-153 510.3 13.5 5.4e-153 510.2 13.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L10 PF00466.20 EGF78174.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ham1p_like PF01725.16 EGF78175.1 - 2.4e-54 184.1 0.0 2.7e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family NADH_dh_m_C1 PF15088.6 EGF78176.1 - 0.23 11.1 0.8 0.62 9.7 0.8 1.7 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial SirB PF04247.12 EGF78176.1 - 1.3 9.2 9.2 0.093 12.8 4.5 1.5 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Methyltransf_10 PF05971.12 EGF78177.1 - 1.3e-66 225.0 0.0 1.6e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGF78177.1 - 3.7e-08 33.1 0.0 6.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGF78177.1 - 0.00032 20.2 0.0 0.00071 19.1 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EGF78177.1 - 0.00071 19.4 0.0 0.00089 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGF78177.1 - 0.017 14.8 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 EGF78177.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGF78177.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGF78177.1 - 0.031 15.0 0.0 0.061 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RYDR_ITPR PF01365.21 EGF78178.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 RIH domain UCH PF00443.29 EGF78180.1 - 1.7e-36 126.0 0.1 2.2e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF78180.1 - 4.5e-16 59.3 0.1 5.9e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase I-EGF_1 PF18372.1 EGF78180.1 - 0.14 12.2 4.4 1.6 8.9 2.2 2.5 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Zn_ribbon_SprT PF17283.2 EGF78180.1 - 1.5 8.8 5.3 0.52 10.3 0.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain AAA_16 PF13191.6 EGF78182.1 - 0.004 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EGF78182.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF78182.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF78182.1 - 0.074 13.3 0.2 0.45 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain OHCU_decarbox PF09349.10 EGF78183.1 - 8.5e-44 149.8 0.3 9.6e-44 149.6 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase F-box-like PF12937.7 EGF78184.1 - 2.8e-14 52.7 2.3 7.5e-14 51.4 2.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF78184.1 - 1e-09 38.0 0.4 2.1e-09 37.0 0.4 1.5 1 0 0 1 1 1 1 F-box domain DnaT PF17948.1 EGF78184.1 - 0.03 14.0 0.2 0.084 12.6 0.2 1.7 1 0 0 1 1 1 0 DnaT DNA-binding domain OmpH PF03938.14 EGF78185.1 - 0.17 12.2 13.6 0.16 12.3 4.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 EGF78185.1 - 0.93 10.1 6.6 0.95 10.1 0.8 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 EGF78185.1 - 1.2 9.1 10.1 0.73 9.9 5.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 EGF78185.1 - 2.3 9.0 6.8 6.5 7.5 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-CHY PF05495.12 EGF78186.1 - 5.3e-19 68.5 20.8 5.3e-19 68.5 20.8 3.9 2 1 1 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 EGF78186.1 - 2.2e-18 66.0 1.4 2.2e-18 66.0 1.4 5.0 3 2 4 7 7 7 1 Zinc-ribbon zf-RING_2 PF13639.6 EGF78186.1 - 1.4e-08 35.0 11.7 1.4e-08 35.0 11.7 5.3 2 1 3 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF78186.1 - 0.00037 20.3 14.2 0.00037 20.3 14.2 6.3 6 2 1 7 7 7 3 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF78186.1 - 0.0025 17.5 7.4 0.0025 17.5 7.4 4.9 6 0 0 6 6 6 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGF78186.1 - 0.0036 17.1 4.5 0.0036 17.1 4.5 5.8 5 2 1 6 6 6 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF78186.1 - 0.019 15.0 10.6 0.019 15.0 10.6 4.6 3 1 0 3 3 3 0 RING-type zinc-finger DUF4246 PF14033.6 EGF78187.1 - 5.1e-29 101.7 0.1 6.4e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUP PF00674.18 EGF78188.1 - 0.024 14.7 1.6 1.6 8.9 0.2 2.7 3 0 0 3 3 3 0 DUP family DUF4246 PF14033.6 EGF78189.1 - 5.5e-93 312.5 0.0 8.9e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arm PF00514.23 EGF78189.1 - 0.0002 21.3 0.0 0.0052 16.8 0.0 3.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HNH_2 PF13391.6 EGF78190.1 - 2.2e-05 24.5 0.2 0.00094 19.3 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease zf-UBP_var PF17807.1 EGF78190.1 - 0.061 13.1 0.2 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger HNH PF01844.23 EGF78190.1 - 1.4 9.1 6.7 2.2 8.5 2.2 3.1 2 1 0 2 2 2 0 HNH endonuclease Cytochrome_C7 PF14522.6 EGF78190.1 - 7.7 6.6 7.5 4.8 7.3 0.6 2.9 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c LRR_8 PF13855.6 EGF78192.1 - 5.4e-11 42.1 4.2 0.00013 21.7 0.4 3.5 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGF78192.1 - 3e-08 33.8 5.0 0.0023 18.3 0.2 3.9 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Complex1_LYR PF05347.15 EGF78193.1 - 8.5e-06 25.7 0.7 1.1e-05 25.3 0.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGF78193.1 - 0.049 14.4 0.0 0.059 14.1 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Eapp_C PF10238.9 EGF78194.1 - 2.3e-44 151.1 8.2 3.2e-44 150.6 8.2 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein zf-B_box PF00643.24 EGF78194.1 - 0.71 10.1 9.3 0.13 12.4 2.5 2.4 2 0 0 2 2 2 0 B-box zinc finger DUF3449 PF11931.8 EGF78195.1 - 6.7e-75 250.9 0.3 6.7e-75 250.9 0.3 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGF78195.1 - 1.9e-23 82.7 5.9 1.9e-23 82.7 5.9 2.7 4 0 0 4 4 4 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EGF78195.1 - 1.6e-10 40.7 0.1 3.9e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EGF78195.1 - 3.8e-07 30.3 5.0 0.00023 21.4 3.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGF78195.1 - 4.2e-07 30.1 3.4 4.2e-07 30.1 3.4 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGF78195.1 - 0.053 13.9 0.5 0.053 13.9 0.5 3.3 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGF78195.1 - 0.39 11.7 3.1 18 6.5 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4246 PF14033.6 EGF78196.1 - 3.7e-61 207.6 0.0 4.2e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RP-C_C PF11800.8 EGF78197.1 - 0.024 14.7 3.0 0.056 13.5 3.0 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region YlbD_coat PF14071.6 EGF78200.1 - 0.015 15.5 5.2 0.015 15.5 5.2 2.0 1 1 1 2 2 2 0 Putative coat protein Histone_HNS PF00816.21 EGF78200.1 - 1.1 10.1 7.2 1.4 9.8 0.4 2.4 1 1 1 2 2 2 0 H-NS histone family BRE1 PF08647.11 EGF78200.1 - 6.8 6.8 11.9 3 8.0 4.0 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Ima1_N PF09779.9 EGF78200.1 - 9.2 7.1 7.7 4 8.3 1.9 2.1 2 0 0 2 2 2 0 Ima1 N-terminal domain zf-CCHC PF00098.23 EGF78201.1 - 6.7e-06 25.9 5.3 1.7e-05 24.6 5.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGF78201.1 - 0.077 12.7 1.0 0.21 11.4 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 EGF78201.1 - 0.077 12.7 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.6 EGF78201.1 - 0.25 11.2 1.4 0.63 9.9 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_20 PF00982.21 EGF78203.1 - 2.9e-156 520.9 0.0 7.1e-156 519.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGF78203.1 - 2.5e-69 233.0 0.0 3.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGF78203.1 - 0.0006 19.6 0.0 0.34 10.6 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HSCB_C PF07743.13 EGF78204.1 - 1.2e-16 60.9 0.9 1.2e-16 60.9 0.9 2.3 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGF78204.1 - 2.8e-08 33.8 0.5 1e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Type_III_YscX PF09474.10 EGF78204.1 - 0.11 12.7 2.4 0.61 10.4 0.5 2.5 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF4795 PF16043.5 EGF78204.1 - 0.76 9.4 7.1 2.6 7.6 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) RRM_1 PF00076.22 EGF78206.1 - 1.5e-07 31.1 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2610 PF11020.8 EGF78207.1 - 0.12 12.3 0.1 2.5 8.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2610) MRNIP PF15749.5 EGF78208.1 - 2.6e-17 63.5 9.4 3.4e-17 63.1 9.4 1.3 1 1 0 1 1 1 1 MRN-interacting protein Ribosomal_S27e PF01667.17 EGF78208.1 - 0.0086 15.8 3.6 0.019 14.7 3.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27 zf-Sec23_Sec24 PF04810.15 EGF78208.1 - 2.7 8.1 7.4 1.7 8.7 4.5 2.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger UPF1_Zn_bind PF09416.10 EGF78209.1 - 5.8e-71 237.4 5.4 5.8e-71 237.4 5.4 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EGF78209.1 - 3.4e-58 196.6 0.0 5.7e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGF78209.1 - 1.3e-52 179.2 3.3 4.6e-29 102.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EGF78209.1 - 1.7e-32 111.5 0.0 3.4e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EGF78209.1 - 1.7e-14 54.0 0.2 9.6e-14 51.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGF78209.1 - 2.1e-10 41.1 0.0 5.5e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGF78209.1 - 2.7e-06 27.3 2.4 0.025 14.3 0.0 3.5 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGF78209.1 - 1.6e-05 24.3 2.0 0.00096 18.5 0.3 3.4 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EGF78209.1 - 4.7e-05 23.3 0.3 0.00037 20.4 0.3 2.3 1 1 0 1 1 1 1 Helicase ResIII PF04851.15 EGF78209.1 - 0.00022 21.3 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 EGF78209.1 - 0.00047 19.4 0.1 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 EGF78209.1 - 0.0035 16.9 3.2 0.067 12.7 0.3 2.9 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EGF78209.1 - 0.014 14.8 0.0 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 EGF78209.1 - 0.022 14.5 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.12 EGF78209.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_10 PF12846.7 EGF78209.1 - 0.045 12.7 0.0 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EGF78209.1 - 0.056 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 EGF78209.1 - 0.091 12.6 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SRP54 PF00448.22 EGF78209.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EGF78209.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 EGF78209.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asp PF00026.23 EGF78211.1 - 6.1e-54 183.6 1.3 7e-54 183.4 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78211.1 - 4.4e-11 43.3 0.0 3.8e-06 27.2 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF78211.1 - 4.8e-05 23.2 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF78211.1 - 0.11 13.0 1.1 15 6.2 0.2 3.5 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 EGF78212.1 - 1.7e-47 162.4 0.2 2.9e-47 161.7 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78212.1 - 1.8e-08 34.8 0.2 5.4e-08 33.3 0.2 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF78212.1 - 0.00017 21.4 0.1 0.005 16.6 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 EGF78213.1 - 1.1e-62 212.3 1.1 1.4e-62 211.9 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78213.1 - 2.3e-09 37.7 1.5 8.5e-07 29.4 0.7 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGF78213.1 - 0.00031 21.3 0.5 1.2 9.9 0.0 3.5 2 1 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EGF78213.1 - 0.00036 20.3 0.1 0.021 14.6 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal UbiA PF01040.18 EGF78214.1 - 3.8e-47 160.7 18.5 4.9e-47 160.3 18.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribonuc_L-PSP PF01042.21 EGF78215.1 - 1.4e-25 89.7 0.0 2.2e-25 89.0 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Gpi16 PF04113.14 EGF78216.1 - 4.3e-169 563.6 0.2 6.3e-168 559.7 0.2 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FAD_binding_3 PF01494.19 EGF78217.1 - 2.4e-26 92.8 0.0 4.4e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGF78217.1 - 2.4e-09 37.2 0.3 1.1e-06 28.5 0.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGF78217.1 - 6.9e-06 26.2 0.2 1.8e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGF78217.1 - 1.2e-05 24.7 0.3 0.00089 18.6 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGF78217.1 - 4.1e-05 22.8 0.0 0.00037 19.6 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase 3HCDH_N PF02737.18 EGF78217.1 - 0.00018 21.4 0.2 0.00028 20.8 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EGF78217.1 - 0.00038 21.0 0.2 0.0017 18.8 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGF78217.1 - 0.00056 19.1 0.3 0.00086 18.5 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGF78217.1 - 0.0012 17.6 0.3 0.0051 15.6 0.3 1.9 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGF78217.1 - 0.0023 17.1 1.4 0.022 13.9 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGF78217.1 - 0.054 12.7 0.6 5.7 6.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGF78217.1 - 0.069 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EGF78217.1 - 0.11 12.1 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGF78217.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 EGF78217.1 - 0.12 11.2 0.2 1.2 7.9 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EGF78217.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Apq12 PF12716.7 EGF78217.1 - 0.46 10.5 3.6 1.2 9.2 3.6 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis COesterase PF00135.28 EGF78218.1 - 1.4e-15 57.2 0.0 2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGF78218.1 - 1.3e-12 48.1 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGF78218.1 - 6.1e-07 29.1 0.5 2.9e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EGF78218.1 - 6.2e-06 25.3 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGF78218.1 - 2.2e-05 23.8 0.7 0.18 11.1 0.2 2.9 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EGF78218.1 - 0.0013 17.8 0.2 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase FSH1 PF03959.13 EGF78218.1 - 0.0069 16.1 0.0 0.019 14.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ubiquitin_4 PF18036.1 EGF78219.1 - 3.3e-10 39.9 0.3 4.3e-08 33.1 0.3 2.4 1 1 0 1 1 1 1 Ubiquitin-like domain FecR PF04773.13 EGF78219.1 - 0.11 13.1 0.1 0.92 10.2 0.0 2.3 3 0 0 3 3 3 0 FecR protein Cyclin_N PF00134.23 EGF78220.1 - 4.7e-20 71.6 0.3 4.9e-19 68.3 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF78220.1 - 2e-08 34.3 2.5 1.6e-06 28.2 1.2 2.9 2 1 0 2 2 2 2 Cyclin, C-terminal domain Med13_C PF06333.12 EGF78221.1 - 0.00039 19.8 0.0 0.00039 19.8 0.0 2.1 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain WH2 PF02205.20 EGF78222.1 - 2.5e-07 30.3 0.0 7.4e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 WH2 motif AKNA PF12443.8 EGF78222.1 - 0.002 18.7 0.3 1.4 9.6 0.0 3.7 4 0 0 4 4 4 2 AT-hook-containing transcription factor IstB_IS21 PF01695.17 EGF78223.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MF_alpha_N PF05436.11 EGF78224.1 - 0.081 12.8 1.6 0.098 12.6 1.6 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Sec2p PF06428.11 EGF78225.1 - 0.055 13.4 3.6 3.8 7.6 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4315 PF14193.6 EGF78225.1 - 0.27 11.3 2.9 0.31 11.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Fib_alpha PF08702.10 EGF78225.1 - 0.4 10.9 5.0 0.98 9.6 0.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TBCA PF02970.16 EGF78225.1 - 0.53 10.7 4.2 15 6.0 0.3 2.6 1 1 1 2 2 2 0 Tubulin binding cofactor A IBR PF01485.21 EGF78226.1 - 0.017 15.3 2.2 0.035 14.3 2.2 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain T_cell_tran_alt PF15128.6 EGF78227.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Asp PF00026.23 EGF78228.1 - 5.6e-18 65.4 0.1 5.1e-17 62.3 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78228.1 - 5.5e-05 23.0 0.0 0.00027 20.7 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4600 PF15372.6 EGF78231.1 - 0.017 15.5 0.7 0.33 11.4 0.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Spc7 PF08317.11 EGF78231.1 - 0.018 14.0 1.0 0.023 13.6 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 EGF78231.1 - 0.037 13.4 1.8 0.065 12.6 1.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 EGF78231.1 - 0.21 10.8 0.5 0.29 10.4 0.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1631 PF07793.11 EGF78231.1 - 0.37 9.1 1.5 0.5 8.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SCP-1 PF05483.12 EGF78231.1 - 0.47 8.4 5.0 0.59 8.1 5.0 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) TMF_DNA_bd PF12329.8 EGF78231.1 - 1.2 9.1 6.3 1.2 9.2 1.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4923 PF16270.5 EGF78233.1 - 0.098 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Tom22 PF04281.13 EGF78234.1 - 0.12 12.2 4.4 0.053 13.3 1.3 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF2981 PF11200.8 EGF78234.1 - 0.54 10.0 3.6 0.16 11.7 0.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DUF4692 PF15763.5 EGF78234.1 - 5.1 7.6 11.3 0.35 11.3 4.7 2.0 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) U3_assoc_6 PF08640.11 EGF78235.1 - 0.071 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Asp PF00026.23 EGF78236.1 - 9.5e-12 45.0 0.2 2.1e-11 43.8 0.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78236.1 - 1.3e-05 25.0 0.0 3.8e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal AAA_16 PF13191.6 EGF78237.1 - 0.0069 16.8 0.0 0.02 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EGF78237.1 - 0.011 16.1 0.0 0.023 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF78237.1 - 0.037 13.8 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF78237.1 - 0.059 13.6 0.1 0.27 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Gp-FAR-1 PF05823.12 EGF78238.1 - 0.0008 19.8 1.7 0.014 15.7 1.4 2.5 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2785 PF10978.8 EGF78238.1 - 0.29 10.9 2.0 0.37 10.5 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Asp PF00026.23 EGF78239.1 - 4.7e-16 59.1 0.2 7e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78239.1 - 0.0016 18.3 0.1 0.41 10.4 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal DUF5462 PF17547.2 EGF78239.1 - 0.1 12.0 0.1 1.6 8.1 0.0 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5462) TAXi_C PF14541.6 EGF78241.1 - 0.00038 20.3 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 EGF78241.1 - 0.0023 17.4 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Pkinase PF00069.25 EGF78242.1 - 6.7e-59 199.4 0.0 8e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78242.1 - 4.7e-34 117.9 0.0 5.8e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78242.1 - 3.4e-09 36.4 0.2 1.3e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGF78242.1 - 6.6e-05 22.9 0.2 0.00013 21.9 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF78242.1 - 0.00043 19.7 0.2 0.00066 19.1 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF78242.1 - 0.0061 15.5 0.1 0.0087 15.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGF78242.1 - 0.039 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGF78242.1 - 0.12 11.9 0.2 8.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2630 PF10944.8 EGF78242.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) RabGAP-TBC PF00566.18 EGF78243.1 - 8.9e-39 133.4 1.4 1.6e-38 132.5 1.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Asp PF00026.23 EGF78245.1 - 2.1e-08 34.0 0.6 1.2e-07 31.4 0.2 2.0 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78245.1 - 0.0021 17.9 0.0 0.0055 16.5 0.0 1.8 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal OPT PF03169.15 EGF78246.1 - 8.2e-132 440.9 51.1 9.3e-132 440.7 51.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 EGF78247.1 - 1.4e-134 450.1 49.0 1.6e-134 449.9 49.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 EGF78247.1 - 5 6.4 5.0 1.3 8.3 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Glutaredoxin PF00462.24 EGF78249.1 - 3.3e-18 65.7 0.0 4.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF656 PF04920.12 EGF78249.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF656) DUF2752 PF10825.8 EGF78249.1 - 0.098 12.7 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) NIF PF03031.18 EGF78250.1 - 5.5e-23 81.5 0.1 1.2e-22 80.4 0.1 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EGF78250.1 - 2.6e-07 30.3 0.0 6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF705 PF05152.12 EGF78250.1 - 0.032 13.7 0.2 0.045 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Ubiquitin_2 PF14560.6 EGF78250.1 - 0.076 13.5 1.2 0.17 12.3 0.4 2.1 2 1 0 2 2 2 0 Ubiquitin-like domain Kinesin PF00225.23 EGF78251.1 - 1.3e-103 346.5 2.0 1.7e-103 346.0 2.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF78251.1 - 2.9e-58 196.0 0.0 6.8e-58 194.8 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF4686 PF15742.5 EGF78251.1 - 0.0023 17.1 0.7 0.004 16.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DEAD PF00270.29 EGF78251.1 - 0.0058 16.4 0.1 0.023 14.4 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Myosin_tail_1 PF01576.19 EGF78251.1 - 0.0059 14.5 1.2 0.0082 14.0 1.2 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 EGF78251.1 - 0.015 14.9 1.5 0.029 14.0 1.5 1.4 1 0 0 1 1 1 0 Intermediate filament protein Tektin PF03148.14 EGF78251.1 - 0.015 14.1 3.1 0.025 13.4 2.1 1.6 1 1 0 1 1 1 0 Tektin family DUF724 PF05266.14 EGF78251.1 - 0.023 14.5 0.2 0.058 13.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fez1 PF06818.15 EGF78251.1 - 0.029 14.8 0.7 0.029 14.8 0.7 1.8 2 0 0 2 2 2 0 Fez1 Laminin_II PF06009.12 EGF78251.1 - 0.03 14.3 2.0 0.03 14.3 2.0 1.9 2 0 0 2 2 1 0 Laminin Domain II SPATA1_C PF15743.5 EGF78251.1 - 0.043 13.9 3.3 0.089 12.9 3.3 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus XhlA PF10779.9 EGF78251.1 - 0.051 13.8 0.5 0.16 12.2 0.5 1.8 1 0 0 1 1 1 0 Haemolysin XhlA CENP-Q PF13094.6 EGF78251.1 - 0.064 13.5 1.6 0.076 13.2 0.4 1.9 2 0 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.12 EGF78251.1 - 0.073 13.4 3.7 0.41 11.0 3.2 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4795 PF16043.5 EGF78251.1 - 0.085 12.5 1.3 0.16 11.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) KxDL PF10241.9 EGF78251.1 - 0.095 13.0 0.8 0.34 11.2 0.8 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein CENP-K PF11802.8 EGF78251.1 - 0.1 12.1 1.4 0.26 10.8 1.4 1.6 1 0 0 1 1 1 0 Centromere-associated protein K betaPIX_CC PF16523.5 EGF78251.1 - 0.11 12.4 1.6 0.73 9.7 1.5 2.3 2 0 0 2 2 2 0 betaPIX coiled coil HIP1_clath_bdg PF16515.5 EGF78251.1 - 0.14 12.8 5.3 0.39 11.3 5.3 1.8 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CREPT PF16566.5 EGF78251.1 - 0.15 12.2 3.4 0.4 10.8 3.4 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour GAS PF13851.6 EGF78251.1 - 0.16 11.3 3.2 0.32 10.3 3.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 EGF78251.1 - 0.16 12.0 7.7 0.061 13.4 4.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 EGF78251.1 - 0.18 12.4 4.8 1.6 9.4 4.4 2.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DUF4404 PF14357.6 EGF78251.1 - 0.19 12.4 1.3 0.59 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3818 PF12825.7 EGF78251.1 - 0.2 10.6 1.1 0.31 10.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) TMPIT PF07851.13 EGF78251.1 - 0.21 10.8 0.9 0.42 9.8 0.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 EGF78251.1 - 0.3 11.7 1.3 0.79 10.4 1.3 1.8 1 0 0 1 1 1 0 SlyX Troponin PF00992.20 EGF78251.1 - 0.34 11.2 3.9 0.67 10.3 3.9 1.4 1 0 0 1 1 1 0 Troponin YabA PF06156.13 EGF78251.1 - 0.34 11.6 8.6 36 5.1 3.6 4.0 3 1 0 3 3 3 0 Initiation control protein YabA Sec2p PF06428.11 EGF78251.1 - 1.3 9.0 7.7 4.5 7.3 5.7 2.8 2 2 0 2 2 2 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 EGF78251.1 - 2.2 8.5 9.0 0.27 11.4 4.4 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF87 PF01935.17 EGF78251.1 - 2.7 8.0 5.8 3.9 7.5 0.2 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain FlgT_M PF16539.5 EGF78252.1 - 0.037 14.1 0.1 0.081 13.1 0.1 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain uDENN PF03456.18 EGF78253.1 - 2.4e-18 66.7 0.6 4e-18 65.9 0.6 1.4 1 0 0 1 1 1 1 uDENN domain DENN PF02141.21 EGF78253.1 - 3.2e-13 50.1 0.0 7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain Esterase PF00756.20 EGF78255.1 - 2.8e-52 177.9 0.0 3.2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGF78255.1 - 4.2e-06 26.4 0.0 5.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGF78255.1 - 0.0029 16.9 0.1 0.0059 15.9 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGF78255.1 - 0.0041 16.6 0.0 0.028 13.9 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 EGF78255.1 - 0.0068 15.4 0.0 0.023 13.6 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EGF78255.1 - 0.021 15.4 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EGF78255.1 - 0.028 13.1 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 EGF78255.1 - 0.051 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 EGF78255.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 EGF78255.1 - 0.079 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 EGF78255.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold GYF PF02213.16 EGF78256.1 - 0.00019 21.0 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 GYF domain DUF2407_C PF13373.6 EGF78256.1 - 0.18 12.0 0.8 0.42 10.8 0.8 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain Porphobil_deam PF01379.20 EGF78257.1 - 4.1e-77 258.3 0.0 5.2e-77 258.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGF78257.1 - 3e-15 56.3 0.0 5.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L14 PF00238.19 EGF78259.1 - 5.5e-36 123.3 0.1 6.4e-36 123.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TAF6_C PF07571.13 EGF78260.1 - 2.5e-28 98.2 0.1 5.2e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EGF78260.1 - 6.2e-25 87.2 0.6 1.4e-24 86.0 0.6 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EGF78260.1 - 0.0077 16.6 2.4 0.011 16.1 0.4 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGF78260.1 - 0.015 15.3 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LysM PF01476.20 EGF78261.1 - 4.7e-18 65.0 0.3 1.7e-10 40.7 0.3 2.3 2 0 0 2 2 2 2 LysM domain TMEM237 PF15383.6 EGF78261.1 - 0.13 11.4 0.2 0.23 10.5 0.0 1.4 2 0 0 2 2 2 0 Transmembrane protein 237 B-block_TFIIIC PF04182.12 EGF78262.1 - 4e-15 55.7 7.6 5.7e-13 48.8 0.1 5.2 5 0 0 5 5 5 1 B-block binding subunit of TFIIIC PHD PF00628.29 EGF78262.1 - 8.5e-06 25.6 8.7 1.9e-05 24.5 8.7 1.6 1 0 0 1 1 1 1 PHD-finger HTH_micro PF17007.5 EGF78262.1 - 3.9e-05 22.7 5.1 0.00014 20.8 0.6 3.3 4 0 0 4 4 4 1 HTH-like CARD PF00619.21 EGF78262.1 - 0.19 11.8 4.9 0.049 13.7 0.5 2.4 3 0 0 3 3 3 0 Caspase recruitment domain Prok-RING_1 PF14446.6 EGF78262.1 - 0.91 9.5 4.4 2 8.4 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HMG_box PF00505.19 EGF78265.1 - 6.4e-13 48.9 11.5 7.2e-11 42.3 1.7 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF78265.1 - 5.7e-09 36.4 4.1 0.0014 19.2 1.1 2.8 2 0 0 2 2 2 2 HMG-box domain LRR_4 PF12799.7 EGF78266.1 - 4.4e-12 46.0 28.4 4.3e-05 23.8 1.2 6.2 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF78266.1 - 1e-10 41.2 29.9 6.4e-09 35.5 2.6 5.5 6 1 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 EGF78266.1 - 0.00091 19.5 15.3 1.6 9.6 0.4 7.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EGF78266.1 - 0.0059 16.6 7.1 3.7 7.9 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 EGF78266.1 - 0.04 13.4 6.2 7.4 6.0 0.2 3.8 3 0 0 3 3 3 0 Leucine-rich repeat Fibrillarin PF01269.17 EGF78267.1 - 3.8e-108 359.8 0.1 4.7e-108 359.5 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGF78267.1 - 9.1e-06 25.5 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGF78267.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EGF78267.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGF78267.1 - 0.042 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4006 PF13179.6 EGF78268.1 - 0.37 10.7 1.4 0.47 10.4 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Ras PF00071.22 EGF78269.1 - 3.9e-58 195.6 0.1 4.7e-58 195.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF78269.1 - 3.9e-22 78.7 0.0 6.6e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF78269.1 - 3.7e-09 36.3 0.0 4.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF78269.1 - 1.3e-06 28.1 0.1 2.7e-06 27.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF78269.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF78269.1 - 0.003 17.5 0.5 2.4 8.0 0.3 2.4 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGF78269.1 - 0.0043 16.6 0.0 0.01 15.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EGF78269.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATPase PF06745.13 EGF78269.1 - 0.058 12.7 0.4 0.12 11.6 0.3 1.6 1 1 0 1 1 1 0 KaiC ATP_bind_1 PF03029.17 EGF78269.1 - 0.14 11.9 2.5 0.59 9.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RF-1 PF00472.20 EGF78271.1 - 6.6e-17 61.5 0.2 1.1e-16 60.8 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain FANCF PF11107.8 EGF78272.1 - 0.0022 17.3 0.2 0.0058 15.9 0.2 1.9 1 1 0 1 1 1 1 Fanconi anemia group F protein (FANCF) Abp2 PF09441.10 EGF78273.1 - 0.00095 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 ARID PF01388.21 EGF78273.1 - 0.0042 17.7 0.0 0.0078 16.9 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.25 EGF78275.1 - 8.8e-76 254.7 0.0 1.1e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78275.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78275.1 - 4.5e-10 39.3 0.0 1e-09 38.2 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF78275.1 - 2.3e-08 33.2 0.8 7.4e-08 31.6 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 EGF78275.1 - 0.00089 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGF78275.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGF78275.1 - 0.019 14.9 0.0 0.12 12.3 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Usp PF00582.26 EGF78276.1 - 4.2e-19 69.4 0.0 1.5e-17 64.4 0.0 2.2 1 1 0 1 1 1 1 Universal stress protein family LuxC PF05893.14 EGF78276.1 - 0.049 12.7 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF4200 PF13863.6 EGF78277.1 - 6.8e-16 58.8 22.1 6.8e-16 58.8 22.1 4.5 3 2 1 5 5 5 2 Domain of unknown function (DUF4200) Glyco_hydro_42M PF08532.10 EGF78277.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain CP12 PF02672.15 EGF78277.1 - 0.19 12.5 2.7 20 6.0 0.8 3.0 2 0 0 2 2 2 0 CP12 domain Spc7 PF08317.11 EGF78277.1 - 0.19 10.6 30.5 0.038 12.9 4.6 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein YkyA PF10368.9 EGF78277.1 - 0.46 10.1 25.9 0.3 10.7 3.9 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF1664 PF07889.12 EGF78277.1 - 1.6 8.8 22.1 0.23 11.5 5.4 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) SBP PF03110.14 EGF78278.1 - 0.095 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 SBP domain DUF676 PF05057.14 EGF78279.1 - 9.7e-25 87.4 0.9 1.8e-24 86.5 0.1 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EGF78279.1 - 1.1e-07 31.8 0.0 3.3e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EGF78279.1 - 0.00072 19.5 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF3657 PF12394.8 EGF78279.1 - 1.2 9.7 4.1 0.78 10.3 0.4 2.6 2 0 0 2 2 2 0 Protein FAM135 DnaJ PF00226.31 EGF78280.1 - 1.3e-07 31.7 2.5 7.6e-06 26.0 0.1 2.6 2 1 1 3 3 3 2 DnaJ domain DUF456 PF04306.13 EGF78280.1 - 0.031 14.6 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 EGF78280.1 - 0.049 13.6 1.1 0.049 13.6 1.1 1.6 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 EGF78280.1 - 0.14 11.9 0.3 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper RPT PF13446.6 EGF78280.1 - 0.14 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein F-box-like PF12937.7 EGF78281.1 - 3.7e-07 29.9 1.4 7e-07 29.0 0.7 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGF78281.1 - 0.00059 19.7 0.3 0.0018 18.1 0.3 1.8 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 EGF78281.1 - 0.18 12.3 1.6 1.7 9.2 0.3 3.3 3 1 1 4 4 4 0 PQQ-like domain Ribosomal_S2 PF00318.20 EGF78282.1 - 6.5e-25 87.6 0.1 2e-11 43.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGF78282.1 - 0.00038 21.7 10.7 0.00069 20.9 10.7 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus DHHC PF01529.20 EGF78283.1 - 5.4 7.1 23.9 0.067 13.3 12.5 2.6 2 2 0 2 2 2 0 DHHC palmitoyltransferase DRIM PF07539.12 EGF78284.1 - 2.4e-168 561.3 0.1 2.4e-168 561.3 0.1 5.1 4 1 1 5 5 5 2 Down-regulated in metastasis HEAT PF02985.22 EGF78284.1 - 1.6e-06 27.9 0.1 75 4.0 0.2 9.1 10 0 0 10 10 10 0 HEAT repeat Sec7_N PF12783.7 EGF78284.1 - 0.00078 19.4 3.3 0.00078 19.4 3.3 4.7 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TAF6_C PF07571.13 EGF78284.1 - 0.0016 18.7 0.1 4.3 7.7 0.0 4.5 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain NUC173 PF08161.12 EGF78284.1 - 0.045 13.4 3.6 9.2 5.9 0.1 5.2 5 0 0 5 5 5 0 NUC173 domain DUF3385 PF11865.8 EGF78284.1 - 6.7 6.6 28.4 0.96 9.3 0.1 7.6 8 0 0 8 8 8 0 Domain of unknown function (DUF3385) TAFII28 PF04719.14 EGF78285.1 - 5.4e-28 96.9 0.0 8.3e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Shadoo PF14999.6 EGF78285.1 - 0.091 12.9 3.1 0.17 12.0 3.1 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective AT_hook PF02178.19 EGF78285.1 - 9.6 6.5 10.3 0.54 10.3 4.5 2.2 2 0 0 2 2 2 0 AT hook motif Inv-AAD PF18785.1 EGF78286.1 - 6e-31 107.0 0.0 9.7e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EGF78286.1 - 3.6e-18 65.3 0.0 4.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGF78286.1 - 2e-06 27.6 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 EGF78286.1 - 0.0037 17.2 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 APOBEC-like N-terminal domain zf-CHCC PF10276.9 EGF78287.1 - 7.8e-13 48.2 0.2 1.6e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain Rrp15p PF07890.12 EGF78289.1 - 9.5e-23 81.0 5.6 9.5e-23 81.0 5.6 2.6 2 2 0 2 2 2 1 Rrp15p ADPRTs_Tse2 PF18648.1 EGF78289.1 - 1.5 8.8 5.6 0.92 9.5 0.1 2.4 2 0 0 2 2 2 0 Tse2 ADP-ribosyltransferase toxins DUF4890 PF16231.5 EGF78289.1 - 9.3 6.8 11.1 1.6 9.3 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4890) zf-CHY PF05495.12 EGF78290.1 - 1e-13 51.6 12.5 3e-13 50.0 12.5 1.6 1 1 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 EGF78290.1 - 0.0021 17.6 6.8 0.83 9.3 0.3 3.2 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger HypA PF01155.19 EGF78290.1 - 0.0044 17.0 1.3 0.0044 17.0 1.3 2.1 1 1 1 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 EGF78290.1 - 0.0045 16.9 11.3 0.14 12.2 7.5 2.3 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 EGF78290.1 - 0.0076 16.3 3.7 0.0076 16.3 3.7 2.4 2 1 0 2 2 2 1 Zinc ribbon domain DUF3797 PF12677.7 EGF78290.1 - 0.062 13.2 0.2 0.062 13.2 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Cys_rich_KTR PF14205.6 EGF78290.1 - 0.066 13.0 10.0 1.1 9.1 0.0 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR Elf1 PF05129.13 EGF78290.1 - 0.076 13.1 11.5 0.2 11.7 7.7 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like C1_4 PF07975.12 EGF78290.1 - 0.12 12.6 13.4 0.88 9.9 3.8 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain Zn_Tnp_IS91 PF14319.6 EGF78290.1 - 0.3 11.1 11.8 1.4 9.0 2.1 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain zinc_ribbon_4 PF13717.6 EGF78290.1 - 0.38 10.7 13.7 4.6 7.2 0.1 3.4 2 1 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 EGF78290.1 - 0.41 10.6 10.4 0.4 10.6 0.7 2.8 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Evr1_Alr PF04777.13 EGF78290.1 - 0.47 11.0 9.0 4 8.0 9.0 2.4 1 1 0 1 1 1 0 Erv1 / Alr family NOB1_Zn_bind PF08772.11 EGF78290.1 - 1 9.6 8.8 0.053 13.7 2.4 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like MCM_OB PF17207.3 EGF78290.1 - 1.5 8.7 5.7 0.52 10.2 1.1 2.0 1 1 1 2 2 2 0 MCM OB domain zf-ribbon_3 PF13248.6 EGF78290.1 - 1.7 8.2 11.7 1.1 8.8 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.26 EGF78290.1 - 2.2 8.9 12.8 2.1 9.0 1.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DpnI PF06044.12 EGF78290.1 - 2.5 7.7 7.0 11 5.6 0.2 2.0 1 1 1 2 2 2 0 Dam-replacing family zf-C2H2_4 PF13894.6 EGF78290.1 - 3.7 8.6 15.0 4.4 8.4 0.3 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 EGF78290.1 - 6.4 7.1 13.2 1.9 8.8 3.9 3.0 1 1 2 3 3 3 0 zinc-ribbon PUF PF00806.19 EGF78291.1 - 6.5e-60 195.6 15.8 7.7e-10 37.9 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.24 EGF78291.1 - 1.8e-08 34.1 3.1 3.9e-08 33.0 3.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGF78291.1 - 1.2e-07 31.5 6.4 3e-07 30.3 6.4 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGF78291.1 - 1e-05 25.2 4.7 1e-05 25.2 4.7 2.7 3 0 0 3 3 3 1 CCCH-type zinc finger CPL PF08144.11 EGF78291.1 - 0.00041 20.7 0.5 1.7 9.0 0.0 3.7 1 1 0 2 2 2 2 CPL (NUC119) domain Torus PF16131.5 EGF78291.1 - 0.00066 20.3 0.1 0.0017 19.1 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 EGF78291.1 - 0.0062 17.0 2.3 0.0062 17.0 2.3 2.0 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger DUF3683 PF12447.8 EGF78291.1 - 0.14 12.2 1.0 3.5 7.8 0.0 3.2 2 2 0 3 3 3 0 Protein of unknown function (DUF3683) RRF PF01765.19 EGF78292.1 - 7e-45 152.9 3.0 1.4e-44 151.9 3.0 1.5 1 0 0 1 1 1 1 Ribosome recycling factor ApoL PF05461.11 EGF78292.1 - 0.11 11.9 2.2 0.097 12.0 0.2 1.8 2 0 0 2 2 2 0 Apolipoprotein L DUF1980 PF09323.10 EGF78292.1 - 0.26 11.2 0.6 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) BOP1NT PF08145.12 EGF78293.1 - 7.2e-111 370.3 7.4 1.3e-110 369.4 7.4 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGF78293.1 - 1.4e-26 92.2 2.8 1.1e-09 38.7 0.2 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78293.1 - 5.9e-08 32.9 0.3 0.0015 18.7 0.1 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 EGF78293.1 - 0.01 14.3 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal LSM14 PF12701.7 EGF78294.1 - 1.3e-24 86.1 0.0 2.1e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EGF78294.1 - 0.0011 19.8 0.3 0.0011 19.8 0.3 4.4 3 1 2 5 5 5 2 FDF domain SM-ATX PF14438.6 EGF78294.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain HSF_DNA-bind PF00447.17 EGF78295.1 - 0.00016 22.3 0.1 0.00038 21.0 0.0 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding DUF4618 PF15397.6 EGF78295.1 - 0.0036 16.8 1.0 0.0045 16.4 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) RNA_pol_Rpb8 PF03870.15 EGF78295.1 - 0.069 13.3 0.4 0.087 13.0 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb8 YabA PF06156.13 EGF78295.1 - 0.17 12.6 2.0 0.21 12.3 1.0 1.6 1 1 0 1 1 1 0 Initiation control protein YabA SAS-6_N PF16531.5 EGF78297.1 - 1.6e-28 99.1 2.8 5.9e-28 97.3 2.8 2.0 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Sas6_CC PF18594.1 EGF78297.1 - 0.0077 16.0 0.1 0.0077 16.0 0.1 3.1 3 0 0 3 3 3 1 Sas6/XLF/XRCC4 coiled-coil domain PspA_IM30 PF04012.12 EGF78297.1 - 0.5 9.9 34.0 3.9 7.0 6.9 4.3 2 2 1 3 3 3 0 PspA/IM30 family DUF812 PF05667.11 EGF78297.1 - 2.9 6.7 43.1 20 3.9 43.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) AAA PF00004.29 EGF78299.1 - 4.5e-41 140.4 0.0 8.4e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF78299.1 - 2e-08 33.9 0.1 3.9e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGF78299.1 - 5.4e-05 23.2 0.1 0.00018 21.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGF78299.1 - 6e-05 23.3 0.0 0.0053 17.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EGF78299.1 - 0.00014 22.3 0.1 0.0028 18.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EGF78299.1 - 0.0006 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGF78299.1 - 0.00081 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGF78299.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGF78299.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF78299.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGF78299.1 - 0.041 14.0 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGF78299.1 - 0.041 13.7 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGF78299.1 - 0.045 13.5 0.2 0.14 11.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF78299.1 - 0.053 13.9 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EGF78299.1 - 0.061 12.7 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGF78299.1 - 0.079 13.5 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGF78299.1 - 0.094 12.6 0.0 13 5.6 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGF78299.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF78299.1 - 0.17 11.6 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain CRM1_C PF08767.11 EGF78300.1 - 5.8e-126 420.0 2.5 5.8e-126 420.0 2.5 3.5 4 2 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EGF78300.1 - 2.1e-40 138.2 4.5 2.1e-40 138.2 4.5 5.2 5 1 1 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGF78300.1 - 4.3e-33 112.8 3.9 1.3e-32 111.3 3.9 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGF78300.1 - 3.2e-28 97.6 3.1 3.3e-28 97.5 0.3 2.7 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGF78300.1 - 2.1e-19 68.7 0.9 2.1e-19 68.7 0.9 1.9 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGF78300.1 - 7.9e-15 54.5 1.4 2.7e-14 52.8 1.4 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain FliH PF02108.16 EGF78300.1 - 0.13 12.4 2.3 0.36 10.9 0.3 2.7 2 0 0 2 2 2 0 Flagellar assembly protein FliH RNA_pol_Rpb4 PF03874.16 EGF78300.1 - 3.1 8.1 5.6 87 3.5 0.1 4.5 4 1 1 5 5 5 0 RNA polymerase Rpb4 Mak10 PF04112.13 EGF78302.1 - 2e-22 79.5 2.5 4.4e-20 71.9 0.1 2.9 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase CHDCT2 PF08074.11 EGF78302.1 - 0.016 15.4 1.0 0.042 14.0 0.2 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain NPV_P10 PF05531.12 EGF78304.1 - 0.015 15.8 0.1 0.021 15.3 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CTD_bind PF04818.13 EGF78304.1 - 0.09 13.6 0.1 1.3 9.9 0.0 2.4 2 1 1 3 3 3 0 RNA polymerase II-binding domain. Med21 PF11221.8 EGF78304.1 - 2 8.6 6.1 8.7 6.6 6.1 2.0 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF2749 PF10907.8 EGF78304.1 - 4.4 7.5 5.4 17 5.7 5.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) RAP1 PF07218.11 EGF78304.1 - 4.4 5.5 13.9 9.1 4.4 10.8 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) SSP160 PF06933.11 EGF78304.1 - 4.9 5.2 18.4 8.4 4.5 18.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ApoLp-III PF07464.11 EGF78305.1 - 0.0057 16.8 0.2 0.59 10.2 0.0 2.1 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Cytochrom_C_2 PF01322.20 EGF78305.1 - 0.018 15.9 1.0 0.03 15.2 1.0 1.3 1 0 0 1 1 1 0 Cytochrome C' Wap1 PF16997.5 EGF78305.1 - 0.038 13.1 0.3 0.05 12.8 0.3 1.1 1 0 0 1 1 1 0 Wap1 domain AP_endonuc_2_N PF07582.12 EGF78305.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus DUF2749 PF10907.8 EGF78305.1 - 1.4 9.2 3.3 3.6 7.8 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) Herpes_capsid PF06112.11 EGF78305.1 - 8 6.5 13.3 14 5.7 13.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-RING_7 PF02591.15 EGF78307.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain BTB_3 PF16017.5 EGF78308.1 - 0.019 15.0 0.1 0.041 14.0 0.1 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF78308.1 - 0.037 14.4 0.5 0.037 14.4 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3888) CTP_transf_like PF01467.26 EGF78309.1 - 2.8e-25 89.2 0.0 3.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like SNARE PF05739.19 EGF78310.1 - 1.2e-13 50.8 3.4 1.2e-13 50.8 3.4 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EGF78310.1 - 0.00039 20.7 9.0 0.066 13.6 3.5 2.3 2 0 0 2 2 2 2 Syntaxin-like protein Syntaxin PF00804.25 EGF78310.1 - 0.00089 19.0 10.6 0.021 14.5 10.6 2.3 1 1 0 1 1 1 1 Syntaxin Stevor PF17410.2 EGF78310.1 - 0.001 18.7 2.4 0.12 11.9 0.2 2.4 2 0 0 2 2 2 2 Subtelomeric Variable Open Reading frame ANTAR PF03861.14 EGF78310.1 - 0.042 13.7 0.2 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 ANTAR domain COG5 PF10392.9 EGF78310.1 - 0.062 13.5 5.4 0.05 13.8 1.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DASH_Dad4 PF08650.10 EGF78310.1 - 0.1 12.6 1.0 3 7.9 0.1 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad4 Cdh1_DBD_1 PF18196.1 EGF78310.1 - 0.11 12.8 5.3 3.8 7.9 0.2 3.1 2 1 1 3 3 3 0 Chromodomain helicase DNA-binding domain 1 HAUS-augmin3 PF14932.6 EGF78310.1 - 0.25 10.9 5.9 0.38 10.3 0.3 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2873 PF11395.8 EGF78310.1 - 0.84 9.5 4.7 1.8 8.5 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) RIFIN PF02009.16 EGF78310.1 - 3.3 7.5 10.8 15 5.4 10.8 1.9 1 1 0 1 1 1 0 Rifin FAM92 PF06730.11 EGF78311.1 - 2.7e-12 46.6 2.5 3.2e-12 46.4 2.5 1.1 1 0 0 1 1 1 1 FAM92 protein LSM PF01423.22 EGF78313.1 - 1.4e-18 66.3 0.1 2e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGF78313.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Acetyltransf_1 PF00583.25 EGF78314.1 - 2.7e-12 47.0 0.0 3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF78314.1 - 3e-10 40.1 0.1 3.5e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF78314.1 - 2.8e-05 24.4 0.0 4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF78314.1 - 3.9e-05 23.5 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGF78314.1 - 0.026 15.2 0.1 0.062 14.0 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain efb-c PF12199.8 EGF78314.1 - 0.096 12.8 0.6 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Gcd10p PF04189.13 EGF78315.1 - 7e-72 242.1 2.0 9.5e-72 241.6 2.0 1.1 1 0 0 1 1 1 1 Gcd10p family ASH PF15780.5 EGF78316.1 - 9.2e-49 163.7 37.0 0.0032 17.6 0.0 28.4 30 1 0 30 30 30 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGF78316.1 - 1.4e-21 76.5 1.0 0.048 13.8 0.0 11.6 13 0 0 13 13 13 5 Flagellar-associated PapD-like DUF1573 PF07610.11 EGF78316.1 - 9.9e-18 64.0 20.4 0.00014 21.9 0.1 16.3 18 0 0 18 18 18 3 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 EGF78316.1 - 4.3e-15 55.5 32.4 3.6 7.5 0.1 18.5 23 0 0 23 23 23 5 MSP (Major sperm protein) domain MYCBPAP PF14646.6 EGF78316.1 - 2.3e-12 46.6 14.8 0.0042 16.1 0.1 10.2 11 1 1 12 12 12 4 MYCBP-associated protein family TMEM131_like PF12371.8 EGF78316.1 - 2.6e-12 46.8 14.8 2.1 8.7 0.0 13.0 15 0 0 15 15 15 6 Transmembrane protein 131-like PapD_N PF00345.20 EGF78316.1 - 5.5e-05 23.1 2.2 0.78 9.7 0.0 5.0 5 0 0 5 5 5 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain Hydin_ADK PF17213.3 EGF78316.1 - 0.0027 18.0 0.0 0.0027 18.0 0.0 2.5 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain PLDc_2 PF13091.6 EGF78317.1 - 4.3e-15 55.8 0.0 3.9e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGF78317.1 - 4.2e-05 23.6 2.1 0.054 13.7 0.2 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif CN_hydrolase PF00795.22 EGF78318.1 - 2.2e-38 132.1 0.0 2.9e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGF78318.1 - 5.2e-23 81.4 0.0 2.8e-22 79.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase C1_1 PF00130.22 EGF78319.1 - 4.9e-11 42.3 11.4 6.7e-11 41.9 11.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 EGF78319.1 - 0.05 13.6 6.7 0.065 13.2 6.7 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon AFOR_C PF01314.18 EGF78319.1 - 0.18 10.8 2.2 0.22 10.5 2.2 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 PHD PF00628.29 EGF78319.1 - 0.31 11.0 11.2 0.49 10.3 11.2 1.3 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 EGF78319.1 - 1 9.5 10.8 8 6.6 11.2 2.0 1 1 1 2 2 2 0 PHD-finger Pkinase PF00069.25 EGF78320.1 - 6.8e-50 169.9 0.1 8.9e-50 169.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78320.1 - 9.9e-26 90.6 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF78320.1 - 8e-06 25.0 0.1 1.1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF78320.1 - 0.00023 20.6 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF78320.1 - 0.00023 20.1 0.0 0.00034 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGF78320.1 - 0.0046 16.1 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGF78320.1 - 0.0075 16.2 0.0 1.5 8.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family COX15-CtaA PF02628.15 EGF78321.1 - 2.9e-103 345.4 11.2 3.3e-103 345.2 11.2 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF373 PF04123.13 EGF78321.1 - 4.4 6.6 10.0 3.3 7.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Chorismate_synt PF01264.21 EGF78322.1 - 3.7e-137 456.4 0.0 4.2e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SGTA_dimer PF16546.5 EGF78323.1 - 2.9e-23 81.4 1.6 5.1e-23 80.6 1.6 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_11 PF13414.6 EGF78323.1 - 2.4e-09 36.7 0.5 5.7e-06 25.9 0.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.28 EGF78323.1 - 1.1e-07 31.3 1.6 0.0029 17.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78323.1 - 2.1e-06 27.4 1.8 0.073 13.2 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF78323.1 - 1.6e-05 24.9 0.9 0.0094 16.3 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF78323.1 - 0.0084 16.7 0.8 0.014 16.1 0.8 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78323.1 - 0.016 15.2 0.5 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78323.1 - 0.031 15.1 0.2 2.4 9.2 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGF78323.1 - 0.049 13.1 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR Bromodomain PF00439.25 EGF78324.1 - 0.0034 17.4 0.1 0.0082 16.2 0.0 1.6 1 1 1 2 2 2 1 Bromodomain Myb_DNA-binding PF00249.31 EGF78326.1 - 0.0017 18.5 0.0 0.002 18.3 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DSBA PF01323.20 EGF78327.1 - 5.8e-27 94.7 0.0 6.9e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Not1 PF04054.15 EGF78328.1 - 1.9e-143 477.9 2.5 4.4e-143 476.7 2.5 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGF78328.1 - 4e-96 320.7 6.6 4e-96 320.7 6.6 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EGF78328.1 - 1.8e-63 213.2 0.5 4.4e-63 211.9 0.5 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EGF78328.1 - 4.6e-51 172.6 1.8 1.6e-50 170.9 1.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EGF78328.1 - 7.8e-41 139.6 1.9 3.5e-40 137.5 0.2 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat GAT PF03127.14 EGF78328.1 - 0.11 12.8 0.0 0.58 10.5 0.0 2.3 1 0 0 1 1 1 0 GAT domain MCM_N PF14551.6 EGF78328.1 - 0.21 12.2 2.1 38 4.9 0.1 3.8 3 0 0 3 3 3 0 MCM N-terminal domain Pkinase PF00069.25 EGF78329.1 - 4.3e-61 206.6 0.0 1.8e-60 204.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78329.1 - 3.4e-28 98.7 0.0 1.1e-27 96.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF78329.1 - 0.00028 19.9 0.2 0.00036 19.6 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF78329.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Atg8 PF02991.16 EGF78331.1 - 3e-48 162.3 0.1 3.6e-48 162.1 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGF78331.1 - 2.8e-08 34.1 0.1 3.6e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 EGF78331.1 - 0.039 13.5 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 HD_3 PF13023.6 EGF78332.1 - 1.1e-35 123.0 0.4 1.2e-35 122.8 0.4 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGF78332.1 - 8.7e-07 28.9 0.1 1.9e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGF78332.1 - 0.0022 18.2 0.2 0.0039 17.4 0.2 1.5 1 1 0 1 1 1 1 HD domain Pyr_redox_2 PF07992.14 EGF78333.1 - 1.1e-10 41.3 0.1 3.3e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGF78333.1 - 0.0004 20.6 0.0 0.00095 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGF78333.1 - 0.0023 17.9 0.1 0.0088 16.0 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGF78333.1 - 0.0065 15.2 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EGF78333.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EGF78333.1 - 0.05 14.2 0.2 9.8 6.8 0.2 3.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGF78333.1 - 0.053 14.0 0.2 6.7 7.2 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 EGF78333.1 - 0.097 11.9 0.1 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 EGF78333.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HOOK PF05622.12 EGF78334.1 - 2e-07 29.6 13.2 1.9e-06 26.4 13.2 1.9 1 1 0 1 1 1 1 HOOK protein Exonuc_VII_L PF02601.15 EGF78334.1 - 0.35 10.4 8.2 0.39 10.2 8.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec20 PF03908.13 EGF78334.1 - 0.41 10.6 5.3 0.34 10.9 2.9 2.0 1 1 1 2 2 2 0 Sec20 DUF4407 PF14362.6 EGF78334.1 - 2.7 7.3 8.2 21 4.3 8.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EGF78334.1 - 6.3 5.6 4.7 6.9 5.5 4.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein E3_binding PF02817.17 EGF78335.1 - 0.0016 18.8 0.1 0.0041 17.4 0.0 1.7 2 0 0 2 2 2 1 e3 binding domain DNA_pol_D_N PF18018.1 EGF78336.1 - 7.6e-42 142.5 0.0 1.4e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EGF78336.1 - 1.4e-33 116.1 0.4 6.3e-33 113.9 0.1 2.3 2 1 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Elong-fact-P_C PF09285.11 EGF78336.1 - 0.01 15.6 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal NT-C2 PF10358.9 EGF78337.1 - 7.4e-24 84.1 0.2 9.1e-24 83.8 0.2 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Nop25 PF09805.9 EGF78338.1 - 3.1e-13 50.4 18.0 4.9e-13 49.7 15.1 1.9 1 1 1 2 2 2 1 Nucleolar protein 12 (25kDa) RTP1_C1 PF10363.9 EGF78339.1 - 1.5e-33 115.3 5.9 7.4e-33 113.1 0.2 3.8 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGF78339.1 - 1.5e-05 24.6 0.5 7.2e-05 22.4 0.3 2.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 Vac14_Fab1_bd PF12755.7 EGF78339.1 - 7.9e-05 23.2 2.0 0.12 13.0 0.0 3.7 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region U3snoRNP10 PF12397.8 EGF78339.1 - 0.00058 20.2 3.4 0.0012 19.1 1.3 2.7 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EGF78339.1 - 0.0047 17.1 0.2 5.1 7.6 0.1 3.7 3 0 0 3 3 3 2 HEAT repeat WD40 PF00400.32 EGF78340.1 - 4.8e-38 128.5 10.0 3.9e-08 33.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78340.1 - 4.6e-18 65.3 2.9 0.00027 21.2 0.0 6.1 1 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF78340.1 - 5.4e-05 23.2 0.1 0.8 9.6 0.0 3.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGF78340.1 - 0.00013 21.4 0.0 0.23 10.8 0.0 2.5 1 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGF78340.1 - 0.00017 20.7 0.4 3.5 6.5 0.1 3.8 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF78340.1 - 0.0023 16.7 0.4 0.015 14.0 0.0 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 FlgD PF03963.14 EGF78341.1 - 0.067 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region DUF2839 PF10999.8 EGF78341.1 - 0.16 12.4 2.7 0.34 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Got1 PF04178.12 EGF78344.1 - 6.9e-33 113.4 13.8 7.7e-33 113.3 13.8 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4064 PF13273.6 EGF78344.1 - 3.3 8.0 14.9 27 5.1 12.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) GLE1 PF07817.13 EGF78345.1 - 4.5e-55 186.6 3.3 1.2e-52 178.7 0.5 3.3 2 1 1 3 3 3 2 GLE1-like protein DUF3584 PF12128.8 EGF78345.1 - 1.2 6.6 36.8 1.7 6.1 36.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4522 PF15022.6 EGF78345.1 - 1.5 9.1 5.6 3.3 8.0 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4522) Med18 PF09637.10 EGF78346.1 - 4.4e-14 52.9 0.0 1.2e-11 45.0 0.0 2.0 1 1 0 1 1 1 1 Med18 protein Ribosomal_L11_N PF03946.14 EGF78347.1 - 5.4e-19 67.8 0.7 8.8e-19 67.1 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGF78347.1 - 1e-16 61.2 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pinin_SDK_memA PF04696.13 EGF78349.1 - 9.1e-27 93.7 8.8 9.1e-27 93.7 8.8 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Arm-DNA-bind_4 PF14657.6 EGF78350.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Arm DNA-binding domain HNH_2 PF13391.6 EGF78351.1 - 6.9e-06 26.1 0.1 0.00035 20.6 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease Cytochrome_C7 PF14522.6 EGF78351.1 - 0.074 13.1 2.0 2.1 8.4 0.8 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF78351.1 - 0.24 11.2 4.2 2.6 7.9 0.1 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF4246 PF14033.6 EGF78352.1 - 4.4e-28 98.6 0.0 5.5e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF928 PF06051.12 EGF78354.1 - 0.036 13.9 0.9 0.036 13.9 0.9 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Glyco_tran_28_C PF04101.16 EGF78354.1 - 0.05 13.6 0.2 0.3 11.1 0.0 2.0 1 1 1 2 2 2 0 Glycosyltransferase family 28 C-terminal domain NAD1 PF18778.1 EGF78354.1 - 0.072 13.2 1.4 2.6 8.1 0.1 2.1 1 1 1 2 2 2 0 Novel AID APOBEC clade 1 AAA_22 PF13401.6 EGF78355.1 - 2.7e-06 27.7 0.0 7.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF78355.1 - 0.00088 19.7 0.0 0.0027 18.1 0.0 1.9 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 EGF78355.1 - 0.0067 16.4 0.0 0.35 10.8 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGF78355.1 - 0.0094 16.0 0.0 5 7.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Ras PF00071.22 EGF78355.1 - 0.062 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 EGF78355.1 - 0.095 13.2 0.1 0.16 12.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EGF78355.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 EGF78355.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Mannosyl_trans PF05007.13 EGF78356.1 - 1.9e-70 237.7 18.8 2.6e-70 237.2 18.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGF78356.1 - 6.9e-15 55.0 8.3 6.9e-15 55.0 8.3 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EGF78356.1 - 4.2e-06 26.7 16.9 4.2e-06 26.7 16.9 2.9 1 1 1 2 2 2 1 Glycosyltransferase family 87 Tim17 PF02466.19 EGF78356.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ARL6IP6 PF15062.6 EGF78356.1 - 2.5 8.3 5.0 9.1 6.5 0.1 3.2 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix CIAPIN1 PF05093.13 EGF78358.1 - 5.7e-25 87.7 9.7 2.2e-24 85.9 9.7 1.9 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_31 PF13847.6 EGF78358.1 - 0.00097 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CTP_transf_like PF01467.26 EGF78359.1 - 1.1e-08 35.4 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Lung_7-TM_R PF06814.13 EGF78360.1 - 0.0023 17.2 0.5 0.81 8.9 0.1 2.2 2 0 0 2 2 2 2 Lung seven transmembrane receptor HIP1_clath_bdg PF16515.5 EGF78360.1 - 0.84 10.3 18.8 3.8 8.2 6.7 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pheromone PF08015.11 EGF78360.1 - 1.7 9.8 7.1 8.6 7.5 1.0 3.0 2 0 0 2 2 2 0 Fungal mating-type pheromone Taxilin PF09728.9 EGF78362.1 - 0.00027 20.3 6.8 0.00034 19.9 6.8 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1640 PF07798.11 EGF78362.1 - 0.0064 16.6 2.2 0.02 14.9 1.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) CC2-LZ PF16516.5 EGF78362.1 - 0.0096 16.3 2.0 0.017 15.5 2.0 1.4 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-H PF05837.12 EGF78362.1 - 0.01 16.3 0.5 0.017 15.6 0.5 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) ATG16 PF08614.11 EGF78362.1 - 0.012 15.8 0.6 0.017 15.4 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 EGF78362.1 - 0.013 15.7 2.7 0.026 14.8 2.7 1.5 1 0 0 1 1 1 0 Tup N-terminal DUF3841 PF12952.7 EGF78362.1 - 0.061 13.1 0.8 0.082 12.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Seryl_tRNA_N PF02403.22 EGF78362.1 - 0.072 13.3 0.8 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 EGF78362.1 - 0.085 11.4 1.9 0.11 11.1 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 EGF78362.1 - 0.15 12.1 3.0 0.15 12.2 0.5 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GluRS_N PF18466.1 EGF78363.1 - 0.024 15.0 0.2 0.062 13.7 0.2 1.6 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain HisKA_3 PF07730.13 EGF78363.1 - 0.027 15.0 0.2 0.056 14.0 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase AAA_16 PF13191.6 EGF78364.1 - 0.0081 16.6 0.0 0.025 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EGF78364.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF78364.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF78364.1 - 0.068 13.4 0.2 0.44 10.8 0.2 2.2 1 1 0 1 1 1 0 AAA domain UCH PF00443.29 EGF78366.1 - 6.6e-37 127.4 0.1 8.3e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF78366.1 - 4.5e-16 59.4 0.1 5.7e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase I-EGF_1 PF18372.1 EGF78366.1 - 0.14 12.2 4.4 1.6 8.9 2.2 2.5 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Zn_ribbon_SprT PF17283.2 EGF78366.1 - 1.5 8.8 5.3 0.52 10.3 0.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain ATP-synt_ab PF00006.25 EGF78367.1 - 3.9e-110 366.6 0.0 5.6e-110 366.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGF78367.1 - 6.4e-45 151.9 0.0 1.8e-44 150.5 0.0 1.8 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGF78367.1 - 6.3e-14 52.3 1.2 1.6e-13 50.9 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Biotin_lipoyl PF00364.22 EGF78367.1 - 0.15 11.9 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme SNF2_N PF00176.23 EGF78368.1 - 9.7e-61 205.4 3.6 1.6e-60 204.7 3.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF78368.1 - 7.3e-17 61.7 0.0 2.4e-16 60.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGF78368.1 - 1e-15 57.3 1.4 1.6e-09 37.5 0.3 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EGF78368.1 - 5.1e-08 33.1 0.0 1.4e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF78368.1 - 0.0001 22.2 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EGF78368.1 - 0.0008 18.7 0.1 0.0065 15.7 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 EGF78368.1 - 0.011 16.0 0.7 0.063 13.5 0.0 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain ToxN_toxin PF13958.6 EGF78368.1 - 0.35 11.1 5.3 0.86 9.8 0.2 3.0 3 0 0 3 3 3 0 Toxin ToxN, type III toxin-antitoxin system zf-AN1 PF01428.16 EGF78369.1 - 4.9e-10 39.4 8.7 6.7e-10 39.0 8.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 EGF78370.1 - 1.6e-14 53.3 0.2 2e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGF78370.1 - 3.2e-05 23.7 0.0 3.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGF78370.1 - 0.00076 19.9 0.0 0.0026 18.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGF78370.1 - 0.0012 18.9 0.0 0.015 15.3 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGF78370.1 - 0.011 15.7 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain YukD PF08817.10 EGF78370.1 - 0.016 15.9 0.0 0.019 15.6 0.0 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PI3K_p85B PF02192.16 EGF78370.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 PI3-kinase family, p85-binding domain PMT PF02366.18 EGF78371.1 - 9.4e-72 241.5 22.8 9.4e-72 241.5 22.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGF78371.1 - 1.4e-63 214.1 10.8 1.4e-63 214.1 10.8 2.4 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGF78371.1 - 1.7e-27 96.5 0.1 2.5e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 MIR domain Nucleos_tra2_C PF07662.13 EGF78371.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.2 2 1 1 3 3 3 0 Na+ dependent nucleoside transporter C-terminus MCM PF00493.23 EGF78372.1 - 2.2e-103 344.2 0.0 3.6e-103 343.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF78372.1 - 7.5e-34 116.3 0.0 1.7e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGF78372.1 - 3.6e-27 94.6 2.6 9.4e-27 93.3 2.6 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGF78372.1 - 3.6e-13 50.0 3.7 8.2e-13 48.9 3.7 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGF78372.1 - 1.9e-07 30.7 0.1 0.00017 21.1 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGF78372.1 - 8.3e-06 25.8 0.1 4.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGF78372.1 - 1e-05 25.4 0.0 3.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGF78372.1 - 0.014 15.2 0.1 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EGF78372.1 - 0.041 14.3 1.5 0.11 12.9 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGF78372.1 - 2.4 8.8 5.1 1.1 10.0 0.6 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal LMBR1 PF04791.16 EGF78374.1 - 1.2e-35 123.5 20.4 4.2e-22 78.7 4.0 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein GPHR_N PF12537.8 EGF78374.1 - 0.036 14.1 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal GPI2 PF06432.11 EGF78375.1 - 3.8e-82 275.9 21.9 4.3e-82 275.7 21.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2976 PF11190.8 EGF78375.1 - 0.36 10.7 4.4 0.42 10.5 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) DEAD PF00270.29 EGF78376.1 - 6.6e-46 156.3 0.4 1.2e-45 155.4 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF78376.1 - 4.5e-34 117.1 0.1 5.2e-33 113.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGF78376.1 - 7e-05 23.2 0.1 0.0012 19.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EGF78376.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGF78376.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGF78376.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 EGF78376.1 - 0.068 12.5 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.14 EGF78376.1 - 0.076 13.0 0.7 0.26 11.3 0.2 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 EGF78376.1 - 0.13 12.6 0.6 0.57 10.4 0.6 2.0 1 1 0 1 1 1 0 AAA domain DUF3767 PF12597.8 EGF78377.1 - 2.6e-22 78.5 0.5 3.3e-22 78.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Adeno_E3_CR2 PF02439.15 EGF78377.1 - 0.33 10.7 0.9 2.4 8.0 0.4 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Lung_7-TM_R PF06814.13 EGF78378.1 - 0.0045 16.3 0.4 2.2 7.5 0.1 2.2 2 0 0 2 2 2 2 Lung seven transmembrane receptor HIP1_clath_bdg PF16515.5 EGF78378.1 - 0.062 13.9 18.8 1.5 9.5 6.8 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2373 PF10180.9 EGF78378.1 - 0.091 12.6 0.4 18 5.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2373) DUF3617 PF12276.8 EGF78378.1 - 0.12 12.7 0.2 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) RestrictionMunI PF11407.8 EGF78378.1 - 0.14 11.9 0.7 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Type II restriction enzyme MunI ABC_tran_CTD PF16326.5 EGF78378.1 - 0.23 11.7 3.8 5 7.5 0.7 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain Pheromone PF08015.11 EGF78378.1 - 5.7 8.1 6.7 43 5.2 0.9 3.1 2 0 0 2 2 2 0 Fungal mating-type pheromone Sec2p PF06428.11 EGF78378.1 - 8.1 6.5 13.5 13 5.9 2.2 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF2951 PF11166.8 EGF78378.1 - 9.2 6.6 6.7 1.6 9.0 0.1 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF2951) HsbA PF12296.8 EGF78379.1 - 0.07 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Jnk-SapK_ap_N PF09744.9 EGF78379.1 - 0.41 10.8 7.1 0.8 9.9 7.1 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 HSCB_C PF07743.13 EGF78381.1 - 1.2e-16 60.9 0.9 1.2e-16 60.9 0.9 2.2 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGF78381.1 - 2.8e-08 33.8 0.5 1e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Type_III_YscX PF09474.10 EGF78381.1 - 0.12 12.7 2.4 0.61 10.4 0.5 2.5 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) DUF4795 PF16043.5 EGF78381.1 - 0.75 9.4 7.1 2.6 7.6 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Cullin PF00888.22 EGF78383.1 - 7.5e-196 652.4 8.9 1.1e-195 651.9 8.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGF78383.1 - 6.7e-27 93.3 1.2 2.2e-26 91.7 1.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Dynein_heavy PF03028.15 EGF78383.1 - 0.085 12.9 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain STAG PF08514.11 EGF78383.1 - 0.33 10.9 6.2 0.034 14.1 1.0 2.1 2 0 0 2 2 2 0 STAG domain NTF2 PF02136.20 EGF78384.1 - 4.7e-31 107.8 0.0 5.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Asp PF00026.23 EGF78385.1 - 2.1e-39 135.8 1.5 8.2e-29 101.0 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78385.1 - 1.5e-06 28.6 0.5 2.3e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF78385.1 - 0.00017 21.4 0.1 0.0005 19.9 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF78385.1 - 0.084 13.5 0.4 14 6.4 0.1 2.5 2 0 0 2 2 2 0 Aspartyl protease Ribosomal_L3 PF00297.22 EGF78386.1 - 9.6e-28 97.2 3.3 1e-24 87.2 2.0 2.8 1 1 2 3 3 3 2 Ribosomal protein L3 WD40 PF00400.32 EGF78387.1 - 7.2e-20 71.0 19.3 5.5e-05 23.9 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78387.1 - 9.8e-06 25.8 0.2 0.00075 19.7 0.1 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Aldedh PF00171.22 EGF78388.1 - 4.6e-151 503.5 1.5 2.3e-90 303.4 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGF78388.1 - 0.0016 18.0 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) DUF4500 PF14937.6 EGF78389.1 - 0.091 12.8 2.2 2.2 8.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) TMEM40 PF15817.5 EGF78389.1 - 0.11 12.2 0.1 0.37 10.6 0.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 40 family DUF5423 PF17461.2 EGF78389.1 - 0.84 8.4 4.1 1.5 7.6 4.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Aldo_ket_red PF00248.21 EGF78392.1 - 7.3e-49 166.5 0.0 3.4e-47 161.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4168 PF13767.6 EGF78393.1 - 0.017 16.3 5.0 11 7.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4168) DUF5304 PF17230.2 EGF78393.1 - 0.062 13.5 0.2 0.1 12.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5304) KAR PF15222.6 EGF78393.1 - 2.8 8.3 13.3 4.9 7.5 6.6 2.5 1 1 1 2 2 2 0 Kidney androgen-regulated UEV PF05743.13 EGF78394.1 - 1.1e-35 122.2 0.1 1.9e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGF78394.1 - 2e-21 75.7 0.1 9.4e-21 73.5 0.0 2.1 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 EGF78394.1 - 0.00012 21.7 0.1 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Baculo_PEP_C PF04513.12 EGF78394.1 - 0.053 13.6 1.0 0.18 11.8 1.0 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SPATA1_C PF15743.5 EGF78394.1 - 0.071 13.2 1.5 0.13 12.3 1.5 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Bacillus_HBL PF05791.11 EGF78394.1 - 0.12 12.2 1.4 0.21 11.4 1.4 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RecG_N PF17190.4 EGF78394.1 - 0.44 11.3 2.4 5.6 7.8 0.1 2.5 2 1 1 3 3 3 0 RecG N-terminal helical domain XhlA PF10779.9 EGF78394.1 - 1.4 9.2 3.5 5.4 7.3 1.0 2.6 1 1 2 3 3 3 0 Haemolysin XhlA Porin_3 PF01459.22 EGF78395.1 - 9.4e-45 153.2 0.0 2.9e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic porin Asp PF00026.23 EGF78396.1 - 1.1e-49 169.6 0.0 1.3e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78396.1 - 9.5e-11 42.2 0.3 1.4e-08 35.2 0.1 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF78396.1 - 0.018 14.8 0.0 0.28 10.9 0.0 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_S24 PF00717.23 EGF78397.1 - 2.7e-05 24.0 0.1 0.00038 20.4 0.1 2.2 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGF78397.1 - 0.034 13.9 0.0 0.074 12.8 0.0 1.6 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 eIF-3c_N PF05470.12 EGF78398.1 - 5.7e-171 569.8 20.1 2.8e-170 567.5 20.1 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGF78398.1 - 4.4e-12 46.4 0.1 4.8e-11 43.1 0.0 2.9 3 1 0 3 3 3 1 PCI domain NitrOD5 PF11537.8 EGF78398.1 - 0.043 14.0 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 Nitrosopumilus output domain 5 Tubulin_3 PF14881.6 EGF78398.1 - 0.06 13.0 0.4 7.5 6.2 0.1 3.2 2 1 1 3 3 3 0 Tubulin domain BORCS7 PF16088.5 EGF78398.1 - 0.64 10.3 11.0 0.21 11.9 3.8 3.3 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 AbiH PF14253.6 EGF78398.1 - 5.8 6.7 6.0 3 7.6 3.1 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH PseudoU_synth_2 PF00849.22 EGF78399.1 - 3.2e-27 95.6 0.6 6.4e-27 94.6 0.1 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase MT0933_antitox PF14013.6 EGF78399.1 - 0.018 15.3 0.2 0.061 13.6 0.2 1.9 1 0 0 1 1 1 0 MT0933-like antitoxin protein RB_B PF01857.20 EGF78400.1 - 2.1e-23 82.8 1.9 8.2e-23 80.9 1.9 2.1 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 EGF78400.1 - 8.4e-13 48.6 0.1 3.9e-12 46.4 0.1 2.2 1 1 0 1 1 1 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.8 EGF78400.1 - 0.23 11.0 0.0 0.23 11.0 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3452) SNF2_N PF00176.23 EGF78401.1 - 4.6e-78 262.4 0.5 7.6e-78 261.7 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF78401.1 - 4.2e-12 46.4 0.0 2.9e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 EGF78401.1 - 0.00054 19.8 8.9 0.0013 18.6 8.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGF78401.1 - 0.0097 15.9 10.4 0.022 14.7 10.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EGF78401.1 - 0.017 15.1 0.2 0.017 15.1 0.2 3.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit zf-RING_6 PF14835.6 EGF78401.1 - 0.042 13.7 7.2 0.092 12.6 7.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EGF78401.1 - 0.12 12.4 5.0 0.56 10.3 5.2 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EGF78401.1 - 0.2 12.0 9.6 0.71 10.2 9.6 2.0 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 EGF78401.1 - 3.4 7.5 8.4 9.8 6.1 8.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGF78401.1 - 4.5 7.5 10.5 12 6.2 10.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ABC_tran PF00005.27 EGF78403.1 - 6.5e-30 104.4 0.0 9.8e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGF78403.1 - 8.6e-20 71.5 0.3 1.2e-19 71.0 0.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGF78403.1 - 2.9e-06 26.9 0.3 0.00035 20.1 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGF78403.1 - 1e-05 24.6 1.2 1.3e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 EGF78403.1 - 0.00043 20.2 0.1 0.092 12.5 0.1 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EGF78403.1 - 0.00055 19.9 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGF78403.1 - 0.0025 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EGF78403.1 - 0.0028 17.4 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF78403.1 - 0.0053 17.0 0.5 0.075 13.3 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGF78403.1 - 0.0091 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGF78403.1 - 0.017 15.5 0.1 0.031 14.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EGF78403.1 - 0.026 15.0 0.0 0.06 13.8 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EGF78403.1 - 0.031 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGF78403.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGF78403.1 - 0.038 13.6 0.0 0.098 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGF78403.1 - 0.085 12.9 0.2 0.72 9.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EGF78403.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 EGF78403.1 - 0.16 12.2 0.2 0.72 10.1 0.2 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGF78403.1 - 0.18 12.2 0.2 1.1 9.6 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aa_trans PF01490.18 EGF78404.1 - 2.5e-64 217.5 29.2 3.2e-64 217.1 29.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 EGF78405.1 - 4.1e-41 141.1 0.0 3.3e-25 88.9 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78405.1 - 1.8e-19 70.0 0.0 8.6e-11 41.6 0.0 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF78405.1 - 0.1 11.9 0.2 3 7.1 0.0 3.0 3 1 0 3 3 3 0 Kinase-like NAD_binding_9 PF13454.6 EGF78405.1 - 0.16 12.0 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pox_A_type_inc PF04508.12 EGF78405.1 - 0.17 11.8 1.6 0.59 10.1 1.6 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PAG PF15347.6 EGF78406.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched gag_pre-integrs PF13976.6 EGF78408.1 - 1.3e-10 41.0 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 EGF78408.1 - 0.0004 20.0 0.3 0.00084 18.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 EGF78408.1 - 0.089 12.5 0.2 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF78408.1 - 0.1 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Vac17 PF17321.2 EGF78408.1 - 0.12 11.8 0.4 1.1 8.7 0.3 2.1 2 0 0 2 2 2 0 Vacuole-related protein 17 Amnionless PF14828.6 EGF78409.1 - 0.0041 16.0 0.0 0.0049 15.8 0.0 1.1 1 0 0 1 1 1 1 Amnionless DUF2981 PF11200.8 EGF78409.1 - 0.1 12.3 0.8 0.12 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4692 PF15763.5 EGF78409.1 - 0.1 13.1 4.5 0.12 12.8 4.5 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SR-25 PF10500.9 EGF78409.1 - 0.13 11.8 5.9 0.16 11.6 5.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tom22 PF04281.13 EGF78409.1 - 0.14 12.0 4.0 0.13 12.1 3.1 1.5 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF1505 PF07403.11 EGF78409.1 - 0.3 11.3 7.2 0.25 11.5 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1505) Cwf_Cwc_15 PF04889.12 EGF78409.1 - 0.81 9.4 5.8 0.95 9.1 5.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein V-ATPase_G_2 PF16999.5 EGF78411.1 - 0.0046 17.4 3.7 0.082 13.3 3.3 2.4 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit D5_N PF08706.11 EGF78411.1 - 0.087 13.1 2.9 0.21 11.9 2.9 1.7 1 0 0 1 1 1 0 D5 N terminal like PG_binding_3 PF09374.10 EGF78411.1 - 0.1 12.9 0.5 5.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Predicted Peptidoglycan domain Phage_Mu_Gam PF07352.12 EGF78411.1 - 0.11 12.4 4.8 0.7 9.8 1.3 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein zf-SAP30 PF13866.6 EGF78411.1 - 0.13 12.4 6.4 0.65 10.1 0.0 3.2 3 0 0 3 3 3 0 SAP30 zinc-finger DUF4709 PF15821.5 EGF78411.1 - 0.17 12.2 6.8 0.12 12.6 2.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Nbl1_Borealin_N PF10444.9 EGF78411.1 - 0.37 10.5 6.4 0.28 10.9 2.8 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Asp PF00026.23 EGF78412.1 - 1.6e-15 57.3 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78412.1 - 3.5e-08 33.4 0.1 1.7e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF78412.1 - 0.14 12.7 0.1 0.6 10.7 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF4246 PF14033.6 EGF78414.1 - 6.9e-29 101.3 0.0 8.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EGF78414.1 - 0.058 13.8 0.0 4 7.9 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Retrotran_gag_2 PF14223.6 EGF78415.1 - 1.4e-08 34.5 1.1 2.3e-08 33.8 1.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 EGF78415.1 - 5.8e-08 32.5 0.1 2.5e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF1539 PF07560.11 EGF78417.1 - 0.02 15.0 0.1 0.63 10.1 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) MatP_C PF17414.2 EGF78417.1 - 0.76 10.0 3.0 2.5 8.3 0.1 3.1 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain PASTA PF03793.19 EGF78419.1 - 1.3 8.9 17.6 14 5.6 0.8 5.3 1 1 3 4 4 4 0 PASTA domain Endomucin PF07010.12 EGF78419.1 - 5.2 7.0 37.0 6.2 6.7 37.0 1.1 1 0 0 1 1 1 0 Endomucin Ribosomal_L4 PF00573.22 EGF78420.1 - 1.7e-40 138.7 1.6 2.8e-40 138.0 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGF78420.1 - 1.1e-27 95.9 1.6 1.2e-25 89.4 0.3 2.4 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain QRPTase_C PF01729.19 EGF78421.1 - 3.1e-55 186.5 0.0 3.8e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGF78421.1 - 2.2e-17 62.9 0.0 7e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Gly_transf_sug PF04488.15 EGF78422.1 - 7.4e-13 49.0 0.1 1.8e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Tmemb_9 PF05434.11 EGF78422.1 - 0.016 15.1 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 TMEM9 DUF3606 PF12244.8 EGF78422.1 - 2.3 8.2 4.4 17 5.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) PLAC8 PF04749.17 EGF78423.1 - 9.6e-24 84.3 17.4 1.1e-23 84.1 17.4 1.0 1 0 0 1 1 1 1 PLAC8 family zf-RING_2 PF13639.6 EGF78424.1 - 8.4e-12 45.2 6.5 1.7e-11 44.2 5.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGF78424.1 - 1.1e-08 34.7 2.4 2.3e-08 33.6 2.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF78424.1 - 4.3e-08 32.9 3.7 7.8e-08 32.1 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF78424.1 - 9.1e-08 31.8 4.7 1.8e-07 30.9 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 EGF78424.1 - 2.8e-07 30.5 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 EGF78424.1 - 2.9e-07 30.7 6.6 2.4e-06 27.8 6.6 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGF78424.1 - 4.6e-05 23.4 0.8 0.00021 21.2 0.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGF78424.1 - 0.00026 21.0 2.2 0.00033 20.6 0.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGF78424.1 - 0.00087 19.2 3.4 0.0015 18.4 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGF78424.1 - 0.0011 18.7 1.9 0.002 17.9 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGF78424.1 - 0.011 15.9 4.1 0.062 13.5 4.1 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EGF78424.1 - 0.033 14.1 3.7 0.055 13.4 3.7 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EGF78424.1 - 0.062 13.2 2.6 0.14 12.0 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGF78424.1 - 0.12 12.2 4.6 0.22 11.3 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGF78424.1 - 0.18 11.5 2.7 0.38 10.4 2.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EGF78424.1 - 0.28 11.3 3.6 0.55 10.4 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EGF78424.1 - 0.32 11.1 2.4 0.93 9.6 2.4 1.8 1 0 0 1 1 1 0 Zinc-finger zf-CHY PF05495.12 EGF78425.1 - 8.4e-10 39.0 23.7 1.2e-09 38.5 8.7 3.9 3 0 0 3 3 3 2 CHY zinc finger zf-CCCH PF00642.24 EGF78425.1 - 7.6e-05 22.5 0.7 0.00021 21.1 0.7 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGF78425.1 - 0.00043 20.2 2.3 0.0012 18.8 2.3 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGF78425.1 - 0.0021 17.8 0.8 0.0059 16.4 0.8 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger DUF1610 PF07754.11 EGF78425.1 - 0.37 10.8 5.0 3.1 7.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) HypA PF01155.19 EGF78425.1 - 4.6 7.3 14.7 2.1 8.4 2.1 3.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Snf7 PF03357.21 EGF78426.1 - 4.4e-44 150.1 24.0 4.4e-44 150.1 24.0 1.8 1 1 1 2 2 2 1 Snf7 YlqD PF11068.8 EGF78426.1 - 0.36 11.2 16.7 2.2 8.6 7.7 2.3 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.12 EGF78426.1 - 2.4 8.3 13.1 1.1 9.3 8.6 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein UvrD_C PF13361.6 EGF78426.1 - 4.4 6.6 9.5 7.6 5.8 9.5 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Lamprin PF06403.11 EGF78427.1 - 0.0011 19.0 31.5 0.058 13.4 13.0 2.6 1 1 1 2 2 2 2 Lamprin PH PF00169.29 EGF78427.1 - 0.0067 16.9 0.0 0.57 10.7 0.0 3.8 4 1 0 4 4 4 1 PH domain GCOM2 PF15328.6 EGF78428.1 - 0.0051 17.2 3.5 0.0083 16.5 3.5 1.5 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 CEP19 PF14933.6 EGF78428.1 - 0.13 12.6 3.2 0.51 10.6 1.8 2.4 2 0 0 2 2 2 0 CEP19-like protein LRR_8 PF13855.6 EGF78429.1 - 3.3e-57 190.1 94.1 2.4e-10 40.0 3.3 9.9 4 2 9 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 EGF78429.1 - 2.1e-39 132.9 67.9 7.2e-07 29.4 2.6 11.2 7 2 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF78429.1 - 1e-10 41.4 32.6 0.00053 19.5 1.6 5.9 2 2 4 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 EGF78429.1 - 4.2e-06 26.6 68.5 1.9 9.3 1.5 15.6 15 3 0 15 15 15 4 Leucine Rich Repeat LRR_6 PF13516.6 EGF78429.1 - 1.8e-05 24.4 59.0 0.77 10.0 0.1 13.8 15 1 1 16 16 16 7 Leucine Rich repeat THUMP PF02926.17 EGF78432.1 - 1.4e-15 57.7 0.2 2.4e-15 56.9 0.1 1.5 2 0 0 2 2 2 1 THUMP domain VEFS-Box PF09733.9 EGF78432.1 - 0.046 13.5 0.2 0.067 13.0 0.2 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein 4HBT PF03061.22 EGF78433.1 - 0.0007 19.9 0.0 0.28 11.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Rhomboid PF01694.22 EGF78434.1 - 0.00041 20.4 16.1 0.00041 20.4 16.1 1.9 2 1 0 2 2 2 1 Rhomboid family zf-CSL PF05207.13 EGF78435.1 - 1.8e-23 82.0 1.3 2.3e-23 81.7 1.3 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 EGF78435.1 - 0.015 15.1 2.9 0.028 14.2 2.9 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Aminotran_1_2 PF00155.21 EGF78436.1 - 4.3e-41 141.3 0.0 1.2e-40 139.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGF78436.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase ILVD_EDD PF00920.21 EGF78436.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Dehydratase family RGS PF00615.19 EGF78437.1 - 5.6e-16 58.9 0.5 8.9e-16 58.2 0.5 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 EGF78439.1 - 3.5e-16 59.5 0.4 5.5e-16 58.9 0.4 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF4718 PF15842.5 EGF78439.1 - 0.011 15.5 0.1 0.07 12.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) DUF2603 PF10788.9 EGF78439.1 - 0.059 13.4 0.3 0.14 12.2 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2603) RGS PF00615.19 EGF78440.1 - 1.1e-26 93.5 6.3 7.9e-13 48.7 0.2 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain L51_S25_CI-B8 PF05047.16 EGF78441.1 - 0.00065 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TPR_1 PF00515.28 EGF78442.1 - 1.4e-09 37.3 0.0 0.01 15.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78442.1 - 5.1e-08 32.4 0.0 0.048 13.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 EGF78442.1 - 0.00028 20.7 0.9 0.00066 19.5 0.3 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.6 EGF78442.1 - 0.0012 19.1 0.7 0.1 12.9 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.31 EGF78442.1 - 0.011 15.8 0.1 0.055 13.6 0.0 2.2 3 0 0 3 3 3 0 DnaJ domain TPR_11 PF13414.6 EGF78442.1 - 0.028 14.1 0.1 3 7.6 0.0 2.7 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 EGF78442.1 - 0.048 13.9 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78442.1 - 0.072 13.2 0.3 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat F1F0-ATPsyn_F PF10791.9 EGF78445.1 - 2.4e-16 60.0 0.5 4.1e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Rtt106 PF08512.12 EGF78447.1 - 5.1e-18 65.3 0.0 9.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EGF78447.1 - 0.0017 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain HSP20 PF00011.21 EGF78448.1 - 1.8e-11 44.1 0.0 3.7e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGF78448.1 - 0.00019 20.9 0.0 0.00033 20.2 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA SH3_1 PF00018.28 EGF78449.1 - 7e-08 32.0 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF78449.1 - 8.8e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF78449.1 - 6.9e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Acetyltransf_10 PF13673.7 EGF78450.1 - 2.2e-13 50.3 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF78450.1 - 4.2e-07 30.2 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 EGF78450.1 - 2e-05 25.3 0.0 5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF78450.1 - 4.2e-05 23.9 0.0 4.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF78450.1 - 0.00037 20.4 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF726 PF05277.12 EGF78451.1 - 1e-81 274.5 0.0 1.2e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.25 EGF78451.1 - 0.00043 20.2 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 EGF78451.1 - 0.00097 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase UPF0565 PF10561.9 EGF78451.1 - 0.075 12.2 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 DUF4200 PF13863.6 EGF78452.1 - 1.2e-27 96.6 12.2 1.2e-27 96.6 12.2 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) Thymopoietin PF08198.11 EGF78453.1 - 1.5e-05 24.5 0.0 4.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Thymopoietin protein Lipase_3 PF01764.25 EGF78454.1 - 4.3e-30 104.4 0.0 9.6e-30 103.3 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGF78454.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EGF78455.1 - 5.6e-35 120.3 0.0 8.7e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGF78455.1 - 9.7e-08 31.8 0.4 0.0033 17.0 0.1 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGF78455.1 - 0.013 14.7 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGF78455.1 - 0.042 13.5 0.3 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EGF78455.1 - 0.046 13.4 0.3 0.079 12.7 0.3 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EGF78455.1 - 0.063 12.8 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 EGF78455.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGF78455.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGF78456.1 - 7.9e-30 103.6 0.1 2.3e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 EGF78456.1 - 8.3e-06 25.5 0.1 0.00018 21.1 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PDH_E1_M PF17831.1 EGF78456.1 - 0.0058 16.2 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Pyruvate dehydrogenase E1 component middle domain DUF1016_N PF17761.1 EGF78456.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 DUF1016 N-terminal domain PGAP1 PF07819.13 EGF78456.1 - 0.079 12.7 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein FYVE PF01363.21 EGF78457.1 - 7.9e-17 61.2 13.2 1.5e-16 60.3 13.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGF78457.1 - 0.0084 16.3 8.7 0.017 15.4 8.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zinc_ribbon_9 PF14369.6 EGF78457.1 - 0.083 13.2 0.7 0.083 13.2 0.7 2.8 2 1 0 2 2 2 0 zinc-ribbon zf-piccolo PF05715.13 EGF78457.1 - 3.3 7.9 10.8 8.8 6.6 10.8 1.8 1 1 0 1 1 1 0 Piccolo Zn-finger zf-B_box PF00643.24 EGF78457.1 - 6.9 6.9 12.8 1.8 8.8 8.2 2.4 2 1 0 2 2 2 0 B-box zinc finger FAD_binding_2 PF00890.24 EGF78459.1 - 2.4e-73 247.6 0.7 3.3e-73 247.2 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EGF78459.1 - 2.8e-23 81.8 0.2 1.5e-22 79.5 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EGF78459.1 - 1.9e-10 40.9 2.7 8.4e-10 38.7 2.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGF78459.1 - 1.8e-08 34.0 0.8 6.2e-07 28.9 0.4 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF78459.1 - 6.1e-08 32.4 0.9 6.1e-08 32.4 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGF78459.1 - 7.3e-08 32.5 3.9 2.2e-07 31.0 0.8 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGF78459.1 - 2.1e-05 23.4 6.6 0.00025 19.9 0.4 2.7 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 EGF78459.1 - 4.2e-05 22.8 3.1 0.0034 16.5 1.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGF78459.1 - 0.0066 15.7 0.9 0.012 14.8 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGF78459.1 - 0.018 14.4 0.3 0.018 14.4 0.3 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EGF78459.1 - 0.061 12.6 0.4 1.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGF78459.1 - 0.073 12.3 2.4 0.21 10.8 0.7 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EGF78459.1 - 0.099 11.7 0.3 0.18 10.8 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EGF78459.1 - 0.12 11.7 1.1 1.5 8.0 0.5 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase TPR_1 PF00515.28 EGF78461.1 - 8.9e-07 28.5 3.9 0.0018 18.0 1.8 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78461.1 - 8.2e-06 25.6 5.3 0.0037 17.3 1.9 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF78461.1 - 0.00016 21.9 2.7 0.54 10.6 0.5 3.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF78461.1 - 0.00019 21.4 1.8 0.21 11.9 0.8 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF78461.1 - 0.013 16.0 0.8 0.49 10.9 0.8 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF78461.1 - 0.053 14.2 5.4 1.6 9.5 0.8 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF78461.1 - 0.3 11.6 0.1 0.3 11.6 0.1 3.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78461.1 - 0.45 10.7 2.6 15 5.9 1.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ist1 PF03398.14 EGF78462.1 - 5.4e-63 211.8 1.4 6e-63 211.6 1.4 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RAP80_UIM PF18282.1 EGF78462.1 - 0.16 11.7 1.4 6.8 6.6 1.3 2.4 1 1 1 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif DUF3653 PF12375.8 EGF78462.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage protein PPR_2 PF13041.6 EGF78463.1 - 1.2e-06 28.6 10.0 0.0032 17.6 0.1 5.6 7 0 0 7 7 7 2 PPR repeat family PPR PF01535.20 EGF78463.1 - 1.7e-05 24.7 11.6 0.0013 18.9 0.1 6.0 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 EGF78463.1 - 1.9e-05 24.6 1.1 0.0036 17.4 0.0 3.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EGF78463.1 - 0.0053 16.1 0.0 0.31 10.4 0.0 2.8 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGF78463.1 - 2.5 7.9 0.0 2.5 7.9 0.0 3.3 4 0 0 4 4 4 0 PPR repeat Tyrosinase PF00264.20 EGF78464.1 - 1.4e-37 130.1 11.4 2.6e-37 129.2 7.9 2.6 2 1 0 2 2 2 1 Common central domain of tyrosinase Condensation PF00668.20 EGF78465.1 - 0.084 11.5 0.0 1.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Condensation domain SET PF00856.28 EGF78466.1 - 2.1e-11 44.5 0.1 5.1e-11 43.3 0.1 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGF78466.1 - 3.2 7.9 13.3 22 5.2 13.3 2.6 1 1 0 1 1 1 0 MYND finger Phi_1 PF04674.12 EGF78468.1 - 1e-40 139.8 2.2 2.1e-40 138.8 2.2 1.6 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region zf-RanBP PF00641.18 EGF78469.1 - 2.6e-28 97.0 25.6 4.1e-11 42.0 5.0 3.3 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 EGF78469.1 - 0.34 11.0 21.8 0.73 9.9 13.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon TackOD1 PF18551.1 EGF78469.1 - 0.65 9.6 19.4 0.6 9.7 0.5 3.3 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 Prim_Zn_Ribbon PF08273.12 EGF78469.1 - 6.4 7.1 17.4 1.2 9.4 1.6 4.3 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.7 EGF78469.1 - 6.6 6.8 22.9 0.79 9.8 8.1 4.3 3 2 2 5 5 5 0 Transposase zinc-ribbon domain HMG-CoA_red PF00368.18 EGF78470.1 - 5.2e-145 483.1 0.7 7.2e-145 482.6 0.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EGF78470.1 - 4.8e-21 75.2 3.9 1.6e-20 73.5 3.9 1.9 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGF78470.1 - 1.5e-10 39.8 4.6 2.5e-10 39.2 4.6 1.2 1 0 0 1 1 1 1 Patched family PheRS_DBD2 PF18554.1 EGF78470.1 - 0.023 14.7 0.5 0.042 13.8 0.5 1.5 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Arf PF00025.21 EGF78472.1 - 3.1e-47 160.3 0.1 3.8e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGF78472.1 - 8.4e-20 71.0 0.0 9.9e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF78472.1 - 7.3e-17 61.7 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGF78472.1 - 1.4e-10 40.9 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGF78472.1 - 3.2e-09 36.5 0.0 3.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGF78472.1 - 1.8e-07 30.6 0.9 0.00011 21.5 0.0 2.6 1 1 2 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGF78472.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF78472.1 - 0.0011 18.6 0.0 0.02 14.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGF78472.1 - 0.0058 16.4 0.0 0.22 11.3 0.0 2.1 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein VirE PF05272.11 EGF78472.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_7 PF12775.7 EGF78472.1 - 0.015 14.8 0.2 0.032 13.7 0.0 1.6 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGF78472.1 - 0.04 14.2 0.1 0.8 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGF78472.1 - 0.09 13.3 0.1 0.2 12.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 EGF78472.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PCI PF01399.27 EGF78473.1 - 3.9e-26 91.6 1.2 1.2e-25 90.0 1.2 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 EGF78473.1 - 0.018 15.1 0.3 18 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_2 PF02230.16 EGF78474.1 - 2.9e-65 220.1 0.0 3.4e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGF78474.1 - 2.4e-08 33.5 1.2 0.0013 18.0 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF78474.1 - 9.8e-06 26.3 0.2 2.7e-05 24.9 0.3 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGF78474.1 - 2e-05 24.4 0.0 0.00012 21.9 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGF78474.1 - 2.6e-05 23.8 2.0 0.00057 19.4 0.1 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 EGF78474.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EGF78474.1 - 0.0047 16.6 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EGF78474.1 - 0.0052 16.5 2.1 4.7 6.8 0.1 3.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGF78474.1 - 0.054 13.3 0.2 0.26 11.1 0.0 1.9 1 1 0 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.14 EGF78474.1 - 0.062 12.6 0.3 1.3 8.3 0.2 2.0 1 1 1 2 2 2 0 Secretory lipase Snf7 PF03357.21 EGF78475.1 - 3e-50 170.2 19.1 3e-50 170.2 19.1 1.4 2 0 0 2 2 2 1 Snf7 CCDC24 PF15669.5 EGF78475.1 - 0.045 13.6 4.1 0.35 10.7 4.1 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family P53_tetramer PF07710.11 EGF78475.1 - 3.5 7.0 7.0 4.8 6.6 0.2 2.7 2 0 0 2 2 2 0 P53 tetramerisation motif Pkinase_Tyr PF07714.17 EGF78476.1 - 4.5e-52 176.9 0.0 8.7e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGF78476.1 - 4.4e-43 147.5 0.0 1.3e-42 146.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain FF PF01846.19 EGF78476.1 - 1.3e-33 114.9 7.3 3.3e-09 36.8 0.1 6.8 6 0 0 6 6 6 5 FF domain LRR_8 PF13855.6 EGF78476.1 - 3e-14 52.5 36.9 2.7e-08 33.5 8.5 3.8 2 1 3 5 5 5 4 Leucine rich repeat WW PF00397.26 EGF78476.1 - 1.5e-13 50.5 19.5 8.2e-08 32.2 2.7 3.0 3 0 0 3 3 3 2 WW domain LRR_4 PF12799.7 EGF78476.1 - 2.3e-09 37.4 19.7 0.00033 21.0 3.4 4.2 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF78476.1 - 3.2e-06 26.9 23.5 3.2 8.7 0.1 7.0 6 0 0 6 6 6 4 Leucine Rich Repeat APH PF01636.23 EGF78476.1 - 0.018 14.9 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.6 EGF78476.1 - 0.22 11.7 14.9 1.1 9.5 0.7 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Tctex-1 PF03645.13 EGF78477.1 - 1.2e-24 86.5 0.3 1.7e-24 86.0 0.3 1.2 1 0 0 1 1 1 1 Tctex-1 family NitrOD1 PF18549.1 EGF78477.1 - 0.14 12.2 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 LIAS_N PF16881.5 EGF78478.1 - 6.1e-18 65.2 1.3 8.5e-18 64.8 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EGF78478.1 - 1.7e-14 54.5 0.1 3.3e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TMP-TENI PF02581.17 EGF78478.1 - 0.039 13.3 0.0 0.16 11.3 0.0 2.0 2 1 1 3 3 3 0 Thiamine monophosphate synthase AdoMet_dc PF02675.15 EGF78478.1 - 0.093 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase HNH_2 PF13391.6 EGF78479.1 - 1.3e-05 25.3 0.2 0.00031 20.8 0.0 2.8 2 0 0 2 2 2 1 HNH endonuclease Macoilin PF09726.9 EGF78483.1 - 0.097 11.2 34.5 0.13 10.8 34.5 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 EGF78483.1 - 3.9 5.6 20.6 4.6 5.4 20.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 EGF78483.1 - 6.7 5.4 20.8 8.6 5.1 20.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain HSP20 PF00011.21 EGF78484.1 - 0.014 15.5 0.0 0.045 13.9 0.0 1.8 1 1 0 1 1 1 0 Hsp20/alpha crystallin family NICE-3 PF07406.11 EGF78484.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 NICE-3 protein ABC_membrane_2 PF06472.15 EGF78485.1 - 4.2e-97 324.7 5.2 6e-97 324.3 5.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGF78485.1 - 2.9e-18 66.7 0.0 6.6e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGF78485.1 - 0.00039 19.9 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGF78485.1 - 0.00074 20.1 0.1 0.0098 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGF78485.1 - 0.0019 17.9 0.0 0.023 14.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGF78485.1 - 0.0033 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF78485.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGF78485.1 - 0.093 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4200 PF13863.6 EGF78485.1 - 0.094 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Rad17 PF03215.15 EGF78485.1 - 0.11 12.4 0.0 0.43 10.5 0.0 1.9 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4246 PF14033.6 EGF78488.1 - 1.1e-82 278.5 0.5 1.4e-82 278.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) CCDC106 PF15794.5 EGF78489.1 - 0.0012 18.6 9.5 0.0012 18.6 9.5 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 106 ImpA_N PF06812.12 EGF78489.1 - 0.2 11.8 2.2 0.65 10.1 2.2 2.0 1 1 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Cytochrom_C PF00034.21 EGF78490.1 - 1.4e-13 51.8 0.0 1.7e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGF78490.1 - 2.8e-06 27.6 1.8 1.4e-05 25.3 1.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGF78490.1 - 0.003 17.3 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c-550 domain Skp1_POZ PF03931.15 EGF78491.1 - 3.6e-10 39.9 0.0 4.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGF78491.1 - 0.006 16.8 0.1 0.0065 16.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.26 EGF78492.1 - 2.3e-34 118.1 0.0 2.5e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.29 EGF78493.1 - 9.3e-36 123.2 0.4 1.7e-35 122.4 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF78493.1 - 1.3e-26 93.1 0.6 5e-26 91.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGF78493.1 - 0.00048 19.9 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 EGF78493.1 - 0.015 14.7 0.8 0.025 13.9 0.1 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2075 PF09848.9 EGF78493.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGF78493.1 - 0.12 12.6 0.9 1.1 9.5 0.4 2.8 2 1 1 3 3 3 0 AAA domain LIM PF00412.22 EGF78494.1 - 3.9e-45 151.9 40.3 1e-14 54.5 4.4 4.2 4 0 0 4 4 4 4 LIM domain Mpp10 PF04006.12 EGF78495.1 - 8.5e-134 447.3 61.8 1.1e-133 446.9 61.8 1.0 1 0 0 1 1 1 1 Mpp10 protein Pertussis_S1 PF02917.14 EGF78495.1 - 0.046 13.5 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Sel1 PF08238.12 EGF78496.1 - 7.7e-28 96.3 40.5 4.1e-07 30.5 0.4 11.8 13 0 0 13 13 13 7 Sel1 repeat TPR_6 PF13174.6 EGF78496.1 - 0.014 16.0 8.5 0.029 15.0 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF78496.1 - 3.3 7.7 8.4 6 6.9 0.0 5.0 8 0 0 8 8 8 0 Tetratricopeptide repeat FAD_binding_2 PF00890.24 EGF78497.1 - 2.4e-126 422.2 2.6 3e-126 421.9 2.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGF78497.1 - 2.2e-42 144.1 2.8 3.3e-42 143.5 2.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EGF78497.1 - 2e-05 23.9 2.1 0.013 14.7 2.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EGF78497.1 - 2.9e-05 23.4 0.6 0.0084 15.4 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 EGF78497.1 - 0.00032 20.0 0.5 0.00093 18.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGF78497.1 - 0.0032 16.8 0.2 0.0059 15.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGF78497.1 - 0.015 14.4 0.1 0.088 11.8 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGF78497.1 - 0.056 13.0 0.7 0.11 12.0 0.7 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGF78497.1 - 0.11 11.2 1.0 0.31 9.7 0.2 2.2 3 0 0 3 3 3 0 HI0933-like protein BNIP2 PF12496.8 EGF78497.1 - 0.2 12.1 0.6 0.43 11.0 0.6 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Gly_radical PF01228.21 EGF78498.1 - 0.036 14.6 0.0 0.23 12.0 0.0 2.4 2 0 0 2 2 2 0 Glycine radical Sec7 PF01369.20 EGF78499.1 - 1e-63 214.4 0.2 1.7e-63 213.6 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGF78499.1 - 8.7e-05 22.5 4.2 0.0026 17.7 0.2 3.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RNase_P_Rpp14 PF01900.19 EGF78500.1 - 0.00013 22.1 0.0 0.00017 21.8 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family DAG1 PF05454.11 EGF78501.1 - 0.017 14.5 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 EGF78501.1 - 0.036 14.9 0.0 0.072 14.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 EGF78501.1 - 0.068 13.0 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 TMIE protein Shisa PF13908.6 EGF78501.1 - 1.2 9.4 4.6 0.9 9.7 0.1 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4203 PF13886.6 EGF78502.1 - 3.3e-34 118.3 36.5 3.3e-34 118.3 36.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Na_H_Exchanger PF00999.21 EGF78503.1 - 1.4e-59 201.8 45.0 1.8e-59 201.4 45.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Rhodanese PF00581.20 EGF78505.1 - 6e-09 36.4 0.0 7.3e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_15 PF00723.21 EGF78506.1 - 9e-57 192.8 0.1 1.1e-56 192.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RNA_pol_A_bac PF01000.26 EGF78507.1 - 2.7e-35 121.1 0.1 9.7e-35 119.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGF78507.1 - 1.1e-20 72.8 0.0 1.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Med21 PF11221.8 EGF78508.1 - 1.6e-28 99.7 2.8 2.7e-28 99.1 2.8 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EGF78508.1 - 0.2 11.7 0.2 0.2 11.7 0.2 2.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Acid_phosphat_B PF03767.14 EGF78509.1 - 0.077 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4205 PF13898.6 EGF78510.1 - 2.3e-99 332.6 0.0 3.8e-99 331.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) FOP_dimer PF09398.10 EGF78510.1 - 0.0026 17.9 0.0 0.0081 16.4 0.0 1.8 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Costars PF14705.6 EGF78511.1 - 6.2e-27 93.6 0.4 6.9e-27 93.4 0.4 1.0 1 0 0 1 1 1 1 Costars DUF4518 PF15008.6 EGF78511.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) UFD1 PF03152.14 EGF78512.1 - 3.3e-74 248.1 0.0 3.7e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PPI_Ypi1 PF07491.11 EGF78513.1 - 3.4e-23 81.2 0.6 3.4e-23 81.2 0.6 2.8 3 1 0 3 3 3 1 Protein phosphatase inhibitor Coiled-coil_56 PF09813.9 EGF78514.1 - 4.6e-05 23.4 0.0 4.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Phage_TAC_7 PF10109.9 EGF78514.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 BIR PF00653.21 EGF78515.1 - 1e-26 93.3 0.7 8.7e-20 71.2 0.0 3.2 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain PyrI_C PF02748.15 EGF78515.1 - 0.059 13.3 0.7 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF853 PF05872.12 EGF78515.1 - 1.3 7.5 5.4 2.5 6.6 5.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) G-alpha PF00503.20 EGF78516.1 - 1.4e-114 383.0 3.4 1.6e-114 382.8 3.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF78516.1 - 1e-15 57.6 3.4 1.9e-11 43.7 0.5 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGF78516.1 - 0.0012 18.2 5.3 0.012 15.0 0.2 2.7 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGF78516.1 - 0.0014 18.8 0.3 2.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 EGF78516.1 - 0.0017 18.1 0.1 0.01 15.6 0.1 2.3 2 0 0 2 2 2 1 CHC2 zinc finger AAA_29 PF13555.6 EGF78516.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF78516.1 - 0.095 12.8 0.1 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EGF78516.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EGF78517.1 - 6.6e-120 400.5 3.2 7.6e-120 400.3 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF78517.1 - 3.4e-15 55.9 6.9 6.9e-12 45.2 0.5 2.8 3 1 0 3 3 3 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EGF78517.1 - 1.1e-05 25.1 0.1 4.8e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EGF78517.1 - 0.0012 18.2 6.2 0.33 10.3 6.2 2.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGF78517.1 - 0.0018 18.5 1.1 1.2 9.4 0.0 2.8 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGF78517.1 - 0.0043 16.6 0.3 2.2 7.8 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF78517.1 - 0.0074 16.4 0.0 5.1 7.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGF78517.1 - 0.014 15.1 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EGF78517.1 - 0.017 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EGF78517.1 - 0.032 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rad17 PF03215.15 EGF78517.1 - 0.06 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 EGF78517.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGF78518.1 - 3.5e-41 140.7 0.0 7.3e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGF78518.1 - 1.3e-18 66.6 0.0 2.8e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGF78518.1 - 2e-11 43.5 0.4 5.6e-11 42.1 0.4 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGF78518.1 - 6.7e-05 23.1 0.0 0.00043 20.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGF78518.1 - 7.7e-05 22.7 0.1 0.00069 19.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF78518.1 - 0.00011 22.6 0.1 0.018 15.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGF78518.1 - 0.00012 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF78518.1 - 0.00053 20.3 0.6 0.12 12.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 EGF78518.1 - 0.0027 17.2 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 EGF78518.1 - 0.0079 16.0 0.5 0.3 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF78518.1 - 0.0082 16.3 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGF78518.1 - 0.0088 15.4 0.0 0.036 13.5 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGF78518.1 - 0.028 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGF78518.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF78518.1 - 0.094 12.2 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGF78518.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGF78518.1 - 0.13 12.9 0.4 0.74 10.4 0.0 2.5 2 2 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 EGF78518.1 - 0.14 11.8 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 EGF78518.1 - 0.15 11.2 0.9 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Phosphoesterase PF04185.14 EGF78519.1 - 1.1e-52 179.4 0.5 1.6e-52 178.9 0.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family Hormone_1 PF00103.20 EGF78521.1 - 0.061 13.1 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 Somatotropin hormone family ARGLU PF15346.6 EGF78521.1 - 0.063 13.2 4.4 0.095 12.6 4.4 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Tropomyosin PF00261.20 EGF78521.1 - 0.09 12.1 7.4 0.27 10.6 7.5 1.6 1 1 0 1 1 1 0 Tropomyosin RT_RNaseH_2 PF17919.1 EGF78521.1 - 0.12 12.4 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase ATG16 PF08614.11 EGF78521.1 - 0.26 11.5 5.6 0.4 10.9 5.6 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HSP20 PF00011.21 EGF78522.1 - 0.013 15.6 0.0 0.045 13.9 0.0 1.9 1 1 0 1 1 1 0 Hsp20/alpha crystallin family NICE-3 PF07406.11 EGF78522.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 NICE-3 protein CBS PF00571.28 EGF78523.1 - 9.5e-29 99.6 0.9 1.6e-06 28.4 0.0 4.4 4 1 0 4 4 4 4 CBS domain Ribosomal_L9_C PF03948.14 EGF78523.1 - 0.12 12.8 0.0 1.6 9.2 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein L9, C-terminal domain TRAM_LAG1_CLN8 PF03798.16 EGF78524.1 - 6.8e-13 48.8 14.6 1.2e-12 48.0 14.6 1.4 1 0 0 1 1 1 1 TLC domain EDR1 PF14381.6 EGF78525.1 - 7.3e-20 71.5 0.0 1.2e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 YihI PF04220.12 EGF78525.1 - 0.08 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) WD40 PF00400.32 EGF78526.1 - 3.9e-30 103.5 32.0 8.8e-06 26.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.6 EGF78526.1 - 3.2e-08 33.4 2.1 2.4e-05 24.0 0.3 2.4 1 1 1 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 EGF78526.1 - 2.8e-07 30.7 1.9 1.9 8.8 0.0 5.0 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF78526.1 - 4.6e-06 25.6 3.4 0.039 12.6 0.1 3.8 2 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGF78526.1 - 0.0012 18.3 0.6 0.023 14.1 0.0 2.4 3 0 0 3 3 3 1 WD40-like domain PALB2_WD40 PF16756.5 EGF78526.1 - 0.0059 15.6 5.1 2.1 7.2 0.1 3.6 3 1 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 EGF78526.1 - 0.0083 15.2 2.7 0.15 11.1 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 EGF78526.1 - 0.025 13.3 2.9 0.22 10.2 0.6 3.5 1 1 1 2 2 2 0 Nup133 N terminal like Nucleoporin_FG PF13634.6 EGF78527.1 - 0.00029 21.6 95.3 0.014 16.2 39.5 5.2 2 1 2 4 4 4 2 Nucleoporin FG repeat region Ten1_2 PF15490.6 EGF78528.1 - 7.9e-33 112.7 0.0 9.5e-33 112.4 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Sld5 PF05916.11 EGF78529.1 - 0.016 15.7 0.0 0.044 14.3 0.0 1.7 2 1 0 2 2 2 0 GINS complex protein MCM PF00493.23 EGF78531.1 - 2.4e-99 331.0 0.0 3.5e-99 330.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF78531.1 - 4.7e-36 123.4 0.6 8.7e-36 122.5 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGF78531.1 - 1.5e-28 99.0 0.3 4e-28 97.7 0.1 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGF78531.1 - 1.2e-11 45.1 1.6 2.8e-11 43.9 0.2 2.4 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 EGF78531.1 - 1e-07 32.0 0.0 3.3e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGF78531.1 - 2.4e-06 27.1 0.1 0.00068 19.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGF78531.1 - 0.00026 20.9 0.0 0.00092 19.1 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGF78531.1 - 0.011 15.5 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 EGF78531.1 - 0.012 16.0 0.1 0.24 11.7 0.1 2.9 2 2 1 3 3 3 0 AAA ATPase domain DJ-1_PfpI PF01965.24 EGF78532.1 - 1.8e-48 164.5 0.2 2e-48 164.3 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family TBP PF00352.21 EGF78533.1 - 2.3e-67 223.0 0.2 1.6e-32 111.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGF78533.1 - 2.2e-05 24.5 0.1 0.21 11.7 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EGF78533.1 - 0.085 12.7 0.1 0.53 10.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) AbrB_C PF18277.1 EGF78533.1 - 0.21 11.2 0.2 9 6.0 0.0 3.0 2 1 1 3 3 3 0 AbrB C-terminal domain Hep_59 PF07052.11 EGF78534.1 - 6.1e-25 88.0 2.1 3.7e-24 85.5 0.1 2.1 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 P16-Arc PF04699.14 EGF78535.1 - 3.7e-44 150.8 0.0 4.2e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 EGF78535.1 - 0.00046 20.5 0.0 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family PGM_PMM_I PF02878.16 EGF78536.1 - 2e-37 128.0 0.0 3.9e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGF78536.1 - 1.7e-21 76.8 0.1 7.8e-21 74.6 0.0 2.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGF78536.1 - 4.5e-15 55.8 0.2 9e-15 54.9 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGF78536.1 - 6.4e-06 26.3 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HNH_2 PF13391.6 EGF78537.1 - 1.8e-06 28.0 0.0 7.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 HNH endonuclease MscS_porin PF12795.7 EGF78537.1 - 0.0015 18.1 12.3 0.0027 17.3 12.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain YscO-like PF16789.5 EGF78537.1 - 0.0033 17.5 1.7 0.0033 17.5 1.7 2.0 2 0 0 2 2 2 1 YscO-like protein DUF3584 PF12128.8 EGF78537.1 - 0.0047 14.5 12.0 0.0059 14.2 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Sec8_exocyst PF04048.14 EGF78537.1 - 0.0061 16.4 2.8 0.26 11.2 0.8 2.4 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain ERM PF00769.19 EGF78537.1 - 0.0068 16.3 8.2 0.01 15.7 8.2 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family SNARE PF05739.19 EGF78537.1 - 0.01 15.8 8.8 0.55 10.3 0.2 3.3 2 1 1 3 3 3 0 SNARE domain Golgin_A5 PF09787.9 EGF78537.1 - 0.012 15.1 4.2 0.012 15.1 4.2 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 Lebercilin PF15619.6 EGF78537.1 - 0.013 15.1 6.4 0.013 15.1 6.4 1.7 2 0 0 2 2 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 EGF78537.1 - 0.02 14.6 4.6 0.05 13.3 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HrpB7 PF09486.10 EGF78537.1 - 0.024 15.0 17.4 0.73 10.2 10.1 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2564 PF10819.8 EGF78537.1 - 0.096 13.1 9.5 0.65 10.4 4.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) TPR_MLP1_2 PF07926.12 EGF78537.1 - 0.1 12.6 16.8 0.14 12.2 10.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein YvbH_ext PF11724.8 EGF78537.1 - 0.12 12.8 0.6 11 6.4 0.1 3.1 2 1 1 3 3 3 0 YvbH-like oligomerisation region DUF1943 PF09172.11 EGF78537.1 - 0.18 11.0 0.2 0.26 10.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DASH_Duo1 PF08651.10 EGF78537.1 - 0.18 11.6 2.7 12 5.8 0.2 3.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 COG2 PF06148.11 EGF78537.1 - 0.24 11.5 6.6 1.5 8.9 2.6 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 EGF78537.1 - 0.3 10.8 14.2 0.2 11.4 6.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) SH3BP5 PF05276.14 EGF78537.1 - 0.31 10.8 8.0 0.49 10.2 2.1 2.2 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) YkyA PF10368.9 EGF78537.1 - 0.38 10.4 5.2 1.8 8.2 5.2 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DLP_helical PF18709.1 EGF78537.1 - 0.38 9.9 5.6 0.13 11.5 2.9 1.5 2 0 0 2 2 2 0 Dynamin-like helical domain GAS PF13851.6 EGF78537.1 - 0.4 10.0 9.7 1.2 8.4 9.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TarH PF02203.15 EGF78537.1 - 0.4 10.6 10.3 1.3 8.9 10.3 1.6 1 1 0 1 1 1 0 Tar ligand binding domain homologue DUF3552 PF12072.8 EGF78537.1 - 0.43 10.0 14.5 0.31 10.4 10.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HemX PF04375.14 EGF78537.1 - 0.45 9.8 7.5 0.75 9.0 7.5 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2524 PF10732.9 EGF78537.1 - 0.47 10.8 5.6 0.15 12.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) HEPN PF05168.14 EGF78537.1 - 0.59 10.3 7.7 2.8 8.1 1.3 2.8 1 1 1 2 2 2 0 HEPN domain HIP1_clath_bdg PF16515.5 EGF78537.1 - 0.61 10.7 11.9 0.14 12.8 3.8 2.8 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Laminin_II PF06009.12 EGF78537.1 - 0.66 10.0 4.8 2.5 8.1 1.1 2.3 1 1 2 3 3 3 0 Laminin Domain II NifW PF03206.14 EGF78537.1 - 0.7 10.4 3.1 13 6.3 0.1 2.5 2 0 0 2 2 2 0 Nitrogen fixation protein NifW DUF3053 PF11254.8 EGF78537.1 - 0.76 9.3 6.1 0.26 10.8 2.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3053) DUF4398 PF14346.6 EGF78537.1 - 0.8 10.4 19.9 1 10.0 13.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4398) Exonuc_VII_L PF02601.15 EGF78537.1 - 0.81 9.2 12.2 1.9 8.0 12.2 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit XhlA PF10779.9 EGF78537.1 - 1 9.6 3.8 2.7 8.3 3.8 1.7 1 0 0 1 1 1 0 Haemolysin XhlA YfdX PF10938.8 EGF78537.1 - 1.4 8.8 6.0 60 3.5 6.1 2.9 1 1 0 1 1 1 0 YfdX protein PTS_IIA PF02255.16 EGF78537.1 - 2 8.5 8.5 18 5.5 0.2 3.2 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit CCDC-167 PF15188.6 EGF78537.1 - 2.2 8.7 7.7 3.3 8.1 7.0 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 EGF78537.1 - 2.3 7.0 10.6 0.77 8.6 6.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 EGF78537.1 - 3.2 7.0 11.4 4.2 6.6 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YnfE PF17452.2 EGF78537.1 - 3.7 7.9 6.4 8.6 6.7 1.4 3.5 3 1 0 3 3 3 0 Uncharacterized YnfE-like WXG100 PF06013.12 EGF78537.1 - 4 7.7 7.7 30 4.9 0.5 3.0 2 1 0 3 3 3 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.20 EGF78537.1 - 4 7.4 8.1 31 4.6 5.7 2.9 2 1 0 2 2 2 0 Prefoldin subunit WEMBL PF05701.11 EGF78537.1 - 5 5.7 17.4 0.77 8.4 12.9 1.7 2 1 0 2 2 1 0 Weak chloroplast movement under blue light AATF-Che1 PF13339.6 EGF78537.1 - 5.1 7.8 8.7 31 5.2 3.3 2.4 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2203 PF09969.9 EGF78537.1 - 8.8 7.1 8.0 8.3 7.2 3.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Pkinase PF00069.25 EGF78538.1 - 6.8e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78538.1 - 3.7e-07 29.7 0.0 6.5e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF78538.1 - 3.9e-05 23.1 0.0 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF78538.1 - 0.00038 20.4 0.1 0.0035 17.3 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF78538.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF78538.1 - 0.019 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DNA_methylase PF00145.17 EGF78539.1 - 3.5e-39 135.1 0.0 1.6e-38 132.9 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase XPG_N PF00752.17 EGF78539.1 - 0.2 12.2 0.0 1.1 9.8 0.0 2.1 2 0 0 2 2 2 0 XPG N-terminal domain DUF4201 PF13870.6 EGF78540.1 - 0.00045 20.0 22.2 0.035 13.8 5.6 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 EGF78540.1 - 0.1 12.6 20.7 1.2 9.1 9.0 3.5 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1726 PF08351.11 EGF78540.1 - 0.16 11.9 0.3 5.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) DUF3450 PF11932.8 EGF78540.1 - 2 7.7 15.6 0.78 9.0 4.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) KxDL PF10241.9 EGF78540.1 - 8.3 6.8 15.3 0.59 10.5 1.8 3.9 1 1 2 3 3 3 0 Uncharacterized conserved protein SlyX PF04102.12 EGF78540.1 - 9.7 6.9 9.5 38 5.0 0.5 4.0 3 1 1 4 4 4 0 SlyX DUF2439 PF10382.9 EGF78541.1 - 3.5e-17 62.5 0.3 9.2e-17 61.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) gag-asp_proteas PF13975.6 EGF78542.1 - 0.063 13.8 0.0 2.3 8.8 0.0 2.3 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGF78542.1 - 0.086 13.5 0.0 0.27 11.9 0.0 1.8 1 1 1 2 2 2 0 Aspartyl protease TBCA PF02970.16 EGF78544.1 - 2.7e-24 85.3 3.7 3.4e-24 85.0 3.7 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A BRF1 PF07741.13 EGF78544.1 - 0.071 13.5 1.0 0.086 13.2 1.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FapA PF03961.13 EGF78544.1 - 0.14 10.8 1.5 0.16 10.5 1.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A MORN PF02493.20 EGF78545.1 - 2.8e-27 93.0 40.4 5.3e-08 32.3 3.1 6.7 7 0 0 7 7 7 5 MORN repeat Cbl_N3 PF02762.14 EGF78545.1 - 0.7 9.8 5.0 2.3 8.2 0.1 3.0 2 1 2 4 4 4 0 CBL proto-oncogene N-terminus, SH2-like domain RhoGEF PF00621.20 EGF78547.1 - 8.7e-37 127.1 1.3 2.6e-36 125.6 1.3 1.9 1 0 0 1 1 1 1 RhoGEF domain C1_1 PF00130.22 EGF78547.1 - 7.6e-08 32.1 4.6 1.5e-07 31.2 4.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EGF78547.1 - 6.4e-07 29.4 1.2 6.4e-07 29.4 1.2 2.2 2 0 0 2 2 2 1 Hr1 repeat RA PF00788.23 EGF78547.1 - 6.6e-06 26.7 0.0 1.8e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 EGF78547.1 - 7e-05 23.3 0.2 0.00098 19.6 0.1 2.7 2 0 0 2 2 2 1 PH domain PH_5 PF15405.6 EGF78547.1 - 0.0006 19.9 0.4 0.0006 19.9 0.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 EGF78547.1 - 0.0082 16.0 0.3 0.027 14.3 0.3 1.9 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EGF78547.1 - 0.013 15.3 1.2 0.34 10.7 1.2 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain zf_C2H2_6 PF18450.1 EGF78547.1 - 0.073 12.8 0.2 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 Zinc Finger domain C1_2 PF03107.16 EGF78547.1 - 0.18 12.1 6.2 0.47 10.8 6.2 1.7 1 0 0 1 1 1 0 C1 domain DZR PF12773.7 EGF78547.1 - 0.45 10.6 5.6 1.1 9.4 5.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.17 EGF78549.1 - 5.6e-28 96.4 5.5 6.7e-28 96.2 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Yae1_N PF09811.9 EGF78550.1 - 1e-09 37.9 5.3 1.7e-09 37.2 5.3 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Rotamase_3 PF13616.6 EGF78551.1 - 6.6e-18 65.3 0.1 2e-17 63.8 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGF78551.1 - 1.1e-13 51.9 0.0 3.5e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF2249 PF10006.9 EGF78551.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Pkinase PF00069.25 EGF78552.1 - 7.3e-73 245.2 0.0 9.2e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78552.1 - 1.7e-36 125.8 0.0 2.3e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78552.1 - 4.9e-08 32.6 0.0 7.2e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF78552.1 - 1.7e-05 24.5 0.2 2.6e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGF78552.1 - 0.00014 20.9 0.2 0.00019 20.5 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGF78552.1 - 0.0024 17.0 0.1 0.0037 16.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGF78552.1 - 0.01 15.8 0.0 0.41 10.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGF78552.1 - 0.1 11.9 0.5 0.22 10.9 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 EGF78553.1 - 7.9e-08 32.5 14.1 5.4e-06 26.7 4.2 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF78553.1 - 0.00013 21.6 10.8 0.001 18.8 6.2 3.3 1 1 1 2 2 2 2 Leucine rich repeat Phage_antitermQ PF06530.12 EGF78553.1 - 0.032 14.1 0.4 0.16 11.9 0.4 2.3 1 0 0 1 1 1 0 Phage antitermination protein Q LRR_6 PF13516.6 EGF78553.1 - 0.034 14.2 10.5 0.36 11.0 0.5 3.9 2 1 1 3 3 3 0 Leucine Rich repeat Rsa3 PF14615.6 EGF78553.1 - 0.068 12.8 0.7 0.28 10.8 0.1 2.4 2 0 0 2 2 2 0 Ribosome-assembly protein 3 LRR_1 PF00560.33 EGF78553.1 - 8.5 7.4 5.8 91 4.2 1.3 3.9 2 1 0 2 2 2 0 Leucine Rich Repeat Peptidase_C97 PF05903.14 EGF78554.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 PPPDE putative peptidase domain RRT14 PF17075.5 EGF78554.1 - 0.027 14.6 0.6 0.047 13.8 0.6 1.3 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 LRAT PF04970.13 EGF78554.1 - 0.074 13.4 0.2 5.9 7.2 0.0 3.1 2 1 0 2 2 2 0 Lecithin retinol acyltransferase TxDE PF18711.1 EGF78554.1 - 0.11 12.6 0.6 0.3 11.3 0.6 1.7 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme BTB_3 PF16017.5 EGF78555.1 - 0.019 15.0 0.1 0.044 13.9 0.1 1.8 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF78555.1 - 0.039 14.4 0.5 0.039 14.4 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3888) DUF918 PF06033.11 EGF78557.1 - 0.0061 16.6 0.0 0.008 16.2 0.0 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) DEAD PF00270.29 EGF78558.1 - 1.3e-36 126.0 0.0 5.1e-35 120.8 0.0 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF78558.1 - 9.8e-18 64.5 0.0 7.5e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF78558.1 - 1.1e-07 32.1 0.0 7.3e-07 29.3 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Apt1 PF10351.9 EGF78558.1 - 4 6.2 29.1 7.9 5.2 29.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain CEP19 PF14933.6 EGF78559.1 - 6.7e-24 85.0 3.7 6.7e-24 85.0 3.7 4.5 4 1 0 4 4 4 1 CEP19-like protein UPF0449 PF15136.6 EGF78559.1 - 0.48 10.9 3.9 0.92 10.0 1.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 PIN_4 PF13638.6 EGF78560.1 - 1.5e-20 73.8 0.0 4.8e-20 72.2 0.0 1.9 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 EGF78560.1 - 5.1e-08 32.7 6.4 5.1e-08 32.7 6.4 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 EGF78560.1 - 0.00071 19.9 0.5 2.3 8.5 0.0 3.3 4 0 0 4 4 4 2 PIN like domain zf-C2H2_3rep PF18868.1 EGF78560.1 - 0.0056 17.4 0.4 0.024 15.3 0.4 2.1 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats EST1 PF10374.9 EGF78560.1 - 0.083 13.5 5.3 14 6.4 0.0 4.2 3 1 1 4 4 4 0 Telomerase activating protein Est1 Cmc1 PF08583.10 EGF78561.1 - 0.011 15.7 1.4 0.02 14.9 1.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Cnn_1N PF07989.11 EGF78562.1 - 3.6e-13 49.5 4.4 3.6e-13 49.5 4.4 7.3 4 1 3 7 7 7 2 Centrosomin N-terminal motif 1 Speriolin_N PF15058.6 EGF78562.1 - 1 9.4 8.0 4.1 7.5 0.5 3.8 3 0 0 3 3 3 0 Speriolin N terminus GFO_IDH_MocA PF01408.22 EGF78564.1 - 3e-10 41.0 0.1 5.1e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF5352 PF17303.2 EGF78564.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5352) SnoaL_4 PF13577.6 EGF78564.1 - 0.13 12.4 0.2 11 6.1 0.0 3.0 3 0 0 3 3 3 0 SnoaL-like domain Ribosomal_L35p PF01632.19 EGF78565.1 - 0.0014 19.1 5.5 0.0014 19.1 5.5 2.2 3 0 0 3 3 3 1 Ribosomal protein L35 AA_permease PF00324.21 EGF78566.1 - 4.1e-127 424.7 40.3 4.9e-127 424.4 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGF78566.1 - 1.4e-39 136.2 42.9 1.7e-39 135.9 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF78567.1 - 7.7e-125 417.2 40.4 8.7e-125 417.0 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGF78567.1 - 1.8e-40 139.1 43.6 2.1e-40 138.9 43.6 1.1 1 0 0 1 1 1 1 Amino acid permease Ribosomal_S2 PF00318.20 EGF78568.1 - 8.8e-58 195.1 5.4 1.6e-33 115.7 0.4 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 zf-AN1 PF01428.16 EGF78569.1 - 3.1e-11 43.3 5.3 3.1e-11 43.3 5.3 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGF78569.1 - 0.0022 18.3 1.5 0.0044 17.3 1.5 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain DUF2256 PF10013.9 EGF78569.1 - 0.36 11.0 6.5 5.6 7.2 1.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) IBR PF01485.21 EGF78569.1 - 1.5 9.1 9.2 8.3 6.7 9.2 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain UPF0547 PF10571.9 EGF78569.1 - 2.3 8.4 10.3 1.8 8.7 0.4 3.1 2 1 1 3 3 3 0 Uncharacterised protein family UPF0547 UQ_con PF00179.26 EGF78570.1 - 1.1e-11 44.5 0.0 1.4e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA PF00004.29 EGF78571.1 - 1.1e-33 116.5 0.0 2.2e-33 115.5 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF78571.1 - 5.1e-13 48.6 0.1 9.8e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGF78571.1 - 4.4e-05 23.3 0.0 9.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGF78571.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGF78571.1 - 0.00044 19.7 0.0 0.00077 18.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EGF78571.1 - 0.0011 19.2 0.0 0.006 16.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGF78571.1 - 0.0018 18.0 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGF78571.1 - 0.0025 17.8 0.0 0.0059 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGF78571.1 - 0.0026 17.9 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGF78571.1 - 0.0064 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EGF78571.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGF78571.1 - 0.0096 16.0 0.0 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGF78571.1 - 0.0096 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGF78571.1 - 0.014 15.8 0.1 0.099 13.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGF78571.1 - 0.018 15.6 0.0 0.041 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGF78571.1 - 0.028 13.9 0.1 0.061 12.8 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EGF78571.1 - 0.034 13.9 0.1 0.6 9.8 0.0 2.5 2 1 1 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 EGF78571.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EGF78571.1 - 0.059 12.9 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF78571.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGF78571.1 - 0.07 12.2 0.3 0.22 10.6 0.1 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EGF78571.1 - 0.074 13.2 0.1 0.27 11.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) MdcG PF10620.9 EGF78571.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG AAA_3 PF07726.11 EGF78571.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGF78571.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 EGF78571.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain CBS PF00571.28 EGF78572.1 - 4.6e-21 75.0 3.4 7.5e-08 32.7 0.1 4.9 4 1 0 4 4 4 4 CBS domain AMMECR1 PF01871.17 EGF78573.1 - 1.4e-48 164.6 0.0 1.7e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 E1-E2_ATPase PF00122.20 EGF78574.1 - 7.9e-19 67.9 0.0 7.9e-19 67.9 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGF78574.1 - 1.6e-16 61.3 0.0 1.5e-09 38.4 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGF78574.1 - 0.0016 18.5 0.0 0.0049 16.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) OppC_N PF12911.7 EGF78574.1 - 0.011 15.7 3.7 0.83 9.7 0.1 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C S6PP PF05116.13 EGF78574.1 - 0.055 13.0 0.1 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Proteasome PF00227.26 EGF78575.1 - 3e-36 124.7 0.0 3.3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_binding_6 PF08030.12 EGF78576.1 - 1.2e-34 119.7 0.0 2.5e-34 118.6 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGF78576.1 - 6.7e-23 80.9 0.0 3.8e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EGF78576.1 - 1.2e-17 64.2 12.9 1.2e-17 64.2 12.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EGF78576.1 - 0.036 14.7 0.0 0.12 13.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGF78576.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain LRR_4 PF12799.7 EGF78577.1 - 3.1e-14 52.8 4.6 4.3e-05 23.8 0.1 3.3 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF78577.1 - 1.1e-13 51.1 0.5 3.3e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGF78577.1 - 6.3e-07 29.1 7.6 0.0018 18.0 3.1 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EGF78577.1 - 0.013 15.5 0.5 11 6.4 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EGF78577.1 - 0.029 14.9 1.7 1.2e+02 3.8 0.0 4.4 5 1 1 6 6 6 0 Leucine Rich Repeat zf-C2H2 PF00096.26 EGF78578.1 - 7.1e-05 23.0 29.3 0.02 15.3 0.3 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF78578.1 - 0.00033 21.0 11.1 1 9.9 0.0 4.9 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF78578.1 - 0.0022 18.7 25.3 0.2 12.6 0.6 5.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 EGF78578.1 - 0.24 11.9 2.9 32 5.1 0.1 3.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FRB_dom PF08771.11 EGF78578.1 - 2.3 8.7 6.4 5.6 7.4 1.4 3.3 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain zf-C2H2_aberr PF17017.5 EGF78578.1 - 2.7 8.1 8.6 4.8 7.3 0.5 3.5 2 2 1 3 3 3 0 Aberrant zinc-finger W2 PF02020.18 EGF78579.1 - 4.9e-14 52.2 0.4 1.1e-13 51.0 0.4 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RabGAP-TBC PF00566.18 EGF78580.1 - 3.6e-12 46.4 7.5 1.7e-11 44.2 7.5 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain ANAPC4_WD40 PF12894.7 EGF78580.1 - 0.00063 20.0 0.0 0.21 11.9 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4407 PF14362.6 EGF78580.1 - 4 6.7 8.4 6.1 6.1 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec7 PF01369.20 EGF78581.1 - 6.4e-71 237.8 1.8 1.2e-70 236.9 0.7 2.2 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGF78581.1 - 2.2e-36 125.1 6.3 3.9e-36 124.3 0.4 3.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGF78581.1 - 1.1e-30 105.3 7.5 1.6e-28 98.4 0.2 5.8 5 1 1 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGF78581.1 - 1.7e-20 73.4 6.5 6.5e-19 68.3 0.2 4.3 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EGF78581.1 - 0.0027 15.9 0.1 0.0043 15.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF1741 PF08427.10 EGF78581.1 - 0.37 10.4 2.3 5.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1741) EF-hand_7 PF13499.6 EGF78582.1 - 8e-12 45.4 0.2 4e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGF78582.1 - 9.6e-11 41.4 0.4 3.6e-07 29.9 0.1 3.0 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF78582.1 - 1.5e-09 36.7 1.3 0.00056 19.3 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGF78582.1 - 3.4e-09 35.9 1.1 2e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGF78582.1 - 0.039 13.5 0.4 0.16 11.5 0.0 2.2 3 0 0 3 3 3 0 EF hand RasGEF PF00617.19 EGF78583.1 - 9.2e-09 35.7 0.3 9.2e-09 35.7 0.3 2.3 3 0 0 3 3 3 1 RasGEF domain S1-P1_nuclease PF02265.16 EGF78584.1 - 8.6e-56 189.6 0.0 1.1e-55 189.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease TP53IP5 PF15331.6 EGF78587.1 - 4.2 7.5 7.6 1.7 8.8 4.8 1.8 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 ATPase PF06745.13 EGF78589.1 - 0.0081 15.5 0.1 0.023 14.0 0.0 1.7 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 EGF78589.1 - 0.0089 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein MeaB PF03308.16 EGF78589.1 - 0.0095 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGF78589.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RHSP PF07999.11 EGF78589.1 - 0.042 12.7 0.2 0.33 9.7 0.1 2.1 2 1 0 2 2 2 0 Retrotransposon hot spot protein DAP3 PF10236.9 EGF78589.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Asp PF00026.23 EGF78590.1 - 1.1e-14 54.7 0.4 1.5e-14 54.2 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78590.1 - 2.1e-07 30.9 0.3 5.5e-07 29.5 0.3 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGF78590.1 - 0.15 12.6 0.1 5 7.8 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease USP7_C2 PF14533.6 EGF78591.1 - 0.019 14.7 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Ndc1_Nup PF09531.10 EGF78592.1 - 0.15 10.7 15.8 0.18 10.5 15.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WDCP PF15390.6 EGF78592.1 - 1.6 7.0 16.0 3.7 5.8 15.9 1.5 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family IstB_IS21 PF01695.17 EGF78593.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MF_alpha_N PF05436.11 EGF78594.1 - 0.19 11.7 1.2 0.34 10.8 1.2 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Fib_alpha PF08702.10 EGF78594.1 - 1.2 9.3 4.1 1.5 9.0 0.3 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 EGF78595.1 - 0.25 11.3 3.2 8.3 6.5 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF78595.1 - 0.73 10.0 5.1 13 6.0 5.0 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IstB_IS21 PF01695.17 EGF78596.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein HBB PF06777.11 EGF78597.1 - 0.044 13.5 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain RRF PF01765.19 EGF78597.1 - 0.06 13.3 0.2 0.06 13.3 0.2 1.9 2 0 0 2 2 2 0 Ribosome recycling factor Chromo_shadow PF01393.19 EGF78598.1 - 1.4e-20 73.2 2.6 3.5e-18 65.4 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGF78598.1 - 4.5e-11 42.5 0.7 4.5e-11 42.5 0.7 2.5 3 1 1 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain PPL5 PF18168.1 EGF78598.1 - 1.1 8.5 5.8 0.92 8.7 4.4 1.6 1 1 1 2 2 2 0 Prim-pol family 5 Terminase_4 PF05119.12 EGF78599.1 - 0.027 14.9 1.6 0.066 13.6 1.6 1.6 1 0 0 1 1 1 0 Phage terminase, small subunit Asp PF00026.23 EGF78601.1 - 3.8e-14 52.8 0.0 5.9e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78601.1 - 1.5e-05 24.9 0.0 0.00019 21.3 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Phage-A118_gp45 PF10653.9 EGF78602.1 - 0.12 12.4 0.3 0.37 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 DUF4246 PF14033.6 EGF78603.1 - 1.4e-94 317.8 0.0 2.1e-94 317.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Actin PF00022.19 EGF78604.1 - 9.4e-86 288.0 0.0 7.2e-84 281.7 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGF78604.1 - 0.002 17.0 0.0 0.7 8.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein RRM_1 PF00076.22 EGF78605.1 - 3.3e-13 49.3 7.9 4.6e-06 26.4 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.22 EGF78606.1 - 0.056 13.7 1.0 4.8 7.7 0.2 4.0 3 0 0 3 3 3 0 HEAT repeat Nexin_C PF08628.12 EGF78608.1 - 1.6e-27 96.3 0.1 9.9e-27 93.7 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PXA PF02194.15 EGF78608.1 - 1.4e-26 93.6 1.0 1.4e-26 93.6 1.0 2.4 2 0 0 2 2 2 1 PXA domain PX PF00787.24 EGF78608.1 - 4.2e-09 36.4 0.2 1.8e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 PX domain C2 PF00168.30 EGF78608.1 - 2.1e-08 34.4 0.0 4.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain RGS PF00615.19 EGF78608.1 - 0.0022 18.3 0.5 0.0061 16.8 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain Peptidase_M24 PF00557.24 EGF78610.1 - 3.4e-20 72.6 0.0 4.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ERG4_ERG24 PF01222.17 EGF78611.1 - 7.1e-142 473.1 22.9 8.1e-142 473.0 22.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family E1-E2_ATPase PF00122.20 EGF78611.1 - 0.37 10.3 1.8 0.53 9.8 0.2 2.0 2 0 0 2 2 2 0 E1-E2 ATPase peroxidase PF00141.23 EGF78612.1 - 8.7e-46 156.5 0.0 1.2e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 EGF78612.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Mtc PF03820.17 EGF78613.1 - 7.1e-130 432.6 0.9 8.1e-130 432.4 0.9 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Nup35_RRM PF05172.13 EGF78614.1 - 3.6e-09 36.5 0.1 1.2e-08 34.9 0.1 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3584 PF12128.8 EGF78614.1 - 0.00094 16.8 5.5 0.00094 16.8 5.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Nup35_RRM_2 PF14605.6 EGF78614.1 - 0.0036 17.3 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EGF78614.1 - 0.087 12.7 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orbi_VP6 PF01516.16 EGF78614.1 - 0.19 11.2 1.5 0.35 10.4 0.2 2.0 2 0 0 2 2 2 0 Orbivirus helicase VP6 DUF1899 PF08953.11 EGF78615.1 - 1.2e-31 108.3 0.4 4.7e-31 106.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGF78615.1 - 1.2e-20 73.1 0.1 2.2e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGF78615.1 - 6.7e-19 67.9 1.9 0.0013 19.5 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78615.1 - 5.9e-08 32.9 0.4 9.4e-06 25.8 0.1 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SHE3 PF17078.5 EGF78615.1 - 0.044 13.5 0.2 0.072 12.8 0.2 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nup160 PF11715.8 EGF78615.1 - 0.093 11.4 0.1 4.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 GMP_synt_C PF00958.22 EGF78616.1 - 1.5e-46 156.3 0.2 3e-46 155.4 0.2 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EGF78616.1 - 6.2e-39 133.7 0.0 2.3e-38 131.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGF78616.1 - 7.8e-10 38.9 0.0 1.9e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 EGF78616.1 - 7e-06 25.3 0.1 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 EGF78616.1 - 0.0048 16.5 0.0 0.0085 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EGF78616.1 - 0.026 14.0 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC sCache_like PF16736.5 EGF78616.1 - 0.094 12.8 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Single Cache-like tRNA_Me_trans PF03054.16 EGF78616.1 - 0.12 11.2 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Proteasome PF00227.26 EGF78617.1 - 2.3e-57 193.6 0.1 2.8e-57 193.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF78617.1 - 6.8e-14 51.2 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Guanylate_cyc PF00211.20 EGF78620.1 - 2.9e-24 85.7 0.3 9.4e-24 84.0 0.2 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain GAF PF01590.26 EGF78620.1 - 4.5e-23 82.3 0.0 4.4e-17 62.9 0.0 2.9 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 EGF78620.1 - 2.5e-13 50.5 0.0 2.2e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 EGF78620.1 - 6.8e-09 36.2 0.0 1.7e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 GAF domain TPR_2 PF07719.17 EGF78620.1 - 0.084 13.0 1.6 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Thiolase_N PF00108.23 EGF78621.1 - 1e-75 254.4 1.5 1.6e-75 253.8 1.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF78621.1 - 1.1e-45 154.3 0.3 2.5e-45 153.1 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain MIF4G_like_2 PF09090.11 EGF78622.1 - 6.7e-45 153.7 2.0 1.1e-44 152.9 2.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 EGF78622.1 - 1.2e-35 123.0 1.5 8.6e-34 117.0 1.5 2.5 1 1 0 1 1 1 1 MIF4G like MIF4G PF02854.19 EGF78622.1 - 0.0047 16.6 1.2 0.017 14.8 0.2 2.5 2 1 0 2 2 2 1 MIF4G domain COX16 PF14138.6 EGF78624.1 - 1.6e-21 76.6 0.0 2.5e-21 76.0 0.0 1.3 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.32 EGF78625.1 - 3.8e-34 116.1 19.2 0.00074 20.3 0.0 12.4 13 0 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78625.1 - 6.7e-13 48.7 1.5 0.041 14.2 0.0 7.7 5 4 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF78625.1 - 3.4e-09 36.5 1.2 0.0001 21.8 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain Kelch_6 PF13964.6 EGF78625.1 - 0.018 15.3 1.1 3.9 7.9 0.0 4.0 4 0 0 4 4 4 0 Kelch motif BBS2_Mid PF14783.6 EGF78625.1 - 0.18 11.8 1.1 10 6.2 0.0 3.8 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region BAT PF15915.5 EGF78625.1 - 0.22 11.4 0.5 28 4.6 0.0 3.4 4 0 0 4 4 4 0 GAF and HTH_10 associated domain Adaptin_N PF01602.20 EGF78626.1 - 6.2e-119 397.9 8.4 7.8e-119 397.6 8.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGF78626.1 - 1.5e-54 184.2 1.9 3e-54 183.3 1.9 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGF78626.1 - 7.7e-31 106.6 0.1 1.6e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGF78626.1 - 3.1e-14 53.1 2.5 7.7e-08 32.6 0.2 4.9 4 3 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EGF78626.1 - 3.9e-07 30.2 10.9 0.075 13.1 0.3 4.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGF78626.1 - 0.00028 20.9 7.6 18 6.0 0.2 6.2 5 0 0 5 5 5 1 HEAT repeat GATase_2 PF00310.21 EGF78626.1 - 0.0027 16.5 0.1 0.0046 15.7 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HEAT_EZ PF13513.6 EGF78626.1 - 0.025 15.1 1.5 0.025 15.1 1.5 3.0 3 0 0 3 3 3 0 HEAT-like repeat Coatomer_b_Cpla PF14806.6 EGF78626.1 - 0.11 12.5 0.0 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform HEAT_PBS PF03130.16 EGF78626.1 - 0.36 11.6 1.4 8.4 7.4 0.6 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Ras PF00071.22 EGF78627.1 - 5e-09 35.9 0.0 2.3e-08 33.8 0.0 1.9 1 1 1 2 2 2 1 Ras family Roc PF08477.13 EGF78627.1 - 2e-08 34.4 0.0 6.2e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGF78627.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGF78627.1 - 0.001 19.1 0.1 0.0027 17.8 0.1 1.8 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EGF78627.1 - 0.0042 17.6 0.4 0.011 16.3 0.1 1.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EGF78627.1 - 0.0091 15.9 0.3 0.02 14.8 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGF78627.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGF78627.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.6 EGF78628.1 - 2e-14 53.7 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF78628.1 - 1.7e-09 38.2 0.0 3.7e-08 34.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF78628.1 - 6.5e-08 32.6 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF78628.1 - 2.6e-07 31.3 0.0 6.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF78628.1 - 3.4e-07 30.8 0.0 5.8e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGF78628.1 - 2.8e-05 24.2 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF78628.1 - 0.00043 19.9 0.0 0.00096 18.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 EGF78628.1 - 0.00045 19.9 0.1 0.00095 18.8 0.1 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EGF78628.1 - 0.003 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 EGF78628.1 - 0.0036 16.4 0.0 0.03 13.4 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme TehB PF03848.14 EGF78628.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB CMAS PF02353.20 EGF78628.1 - 0.0082 15.5 0.0 0.068 12.4 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 EGF78628.1 - 0.094 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Fe-S_biosyn PF01521.20 EGF78629.1 - 1.9e-18 66.7 0.0 3.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis FHA PF00498.26 EGF78630.1 - 4.2e-16 59.0 0.0 1.6e-15 57.2 0.0 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGF78630.1 - 7.4e-05 23.0 0.0 0.00031 21.0 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LPP PF04728.13 EGF78630.1 - 0.022 15.2 2.2 0.022 15.2 2.2 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Fumble PF03630.14 EGF78630.1 - 0.052 12.7 4.6 0.046 12.9 2.7 1.9 1 1 0 1 1 1 0 Fumble DUF1664 PF07889.12 EGF78630.1 - 0.17 11.9 20.7 1.4 9.0 0.3 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) YscO-like PF16789.5 EGF78630.1 - 0.73 9.9 7.9 2.9 7.9 7.9 2.1 1 0 0 1 1 1 0 YscO-like protein BLOC1_2 PF10046.9 EGF78630.1 - 0.77 10.1 11.9 0.69 10.2 0.3 4.2 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EGF78630.1 - 0.88 9.6 14.4 0.5 10.4 2.0 3.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EGF78630.1 - 1.3 9.4 8.1 1.3 9.5 0.2 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) RPW8 PF05659.11 EGF78630.1 - 3.6 7.3 10.2 1.5 8.5 1.0 3.4 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RRM_1 PF00076.22 EGF78631.1 - 6.4e-15 54.7 0.2 8.7e-11 41.5 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF775 PF05603.12 EGF78631.1 - 0.04 13.4 1.0 1.9 7.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Dicty_CAR PF05462.11 EGF78632.1 - 0.00055 19.2 16.1 0.0088 15.2 16.1 2.0 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 EGF78632.1 - 0.0044 16.4 11.7 0.0062 15.9 11.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EGF78632.1 - 0.0053 16.6 5.7 0.0053 16.6 5.7 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DUF2852 PF11014.8 EGF78632.1 - 0.21 11.7 0.8 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) GPR_Gpa2_C PF11970.8 EGF78632.1 - 6.8 6.8 7.7 0.38 10.9 1.5 2.1 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Cu-binding_MopE PF11617.8 EGF78635.1 - 2.2e-07 30.9 1.1 4.9e-07 29.8 1.1 1.6 1 0 0 1 1 1 1 Putative metal-binding motif Polysacc_deac_1 PF01522.21 EGF78635.1 - 2.6e-07 30.6 0.2 8.1e-07 29.0 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase zf_ZIC PF18366.1 EGF78635.1 - 0.034 14.2 0.4 0.066 13.3 0.4 1.4 1 0 0 1 1 1 0 Zic proteins zinc finger domain rRNA_proc-arch PF13234.6 EGF78636.1 - 1e-76 258.5 0.0 1.8e-76 257.7 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EGF78636.1 - 1.2e-51 174.7 1.1 1.6e-51 174.3 0.1 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EGF78636.1 - 1.9e-19 70.1 0.0 4.5e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF78636.1 - 2.9e-06 27.6 0.0 2.5e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGF78636.1 - 0.04 14.2 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RDM PF11002.8 EGF78636.1 - 0.067 13.2 0.8 0.74 9.9 0.1 2.7 2 0 0 2 2 2 0 RFPL defining motif (RDM) MRP-S25 PF13741.6 EGF78639.1 - 2e-27 96.3 3.6 1.4e-25 90.2 3.6 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EGF78639.1 - 0.00061 20.0 3.2 0.032 14.5 0.0 3.1 3 0 0 3 3 3 1 Mitochondrial ribosomal protein S23 RPA_interact_M PF14767.6 EGF78639.1 - 0.028 15.0 1.2 0.44 11.1 1.2 2.4 1 1 0 1 1 1 0 Replication protein A interacting middle Phage_lambda_P PF06992.11 EGF78639.1 - 0.032 14.0 0.6 0.063 13.0 0.6 1.5 1 0 0 1 1 1 0 Replication protein P PPR PF01535.20 EGF78640.1 - 0.0036 17.4 0.0 15 6.1 0.0 5.2 6 0 0 6 6 6 1 PPR repeat TPR_1 PF00515.28 EGF78640.1 - 0.0051 16.6 1.3 0.94 9.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ATP13 PF12921.7 EGF78640.1 - 0.0098 15.7 1.3 0.22 11.4 0.4 3.1 3 0 0 3 3 3 1 Mitochondrial ATPase expression TPR_8 PF13181.6 EGF78640.1 - 0.014 15.6 0.3 53 4.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78640.1 - 0.037 14.1 1.4 5.2 7.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 EGF78640.1 - 0.05 13.3 4.4 32 4.3 0.0 4.7 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain PPR_3 PF13812.6 EGF78641.1 - 2.6e-06 27.4 4.8 1e-05 25.5 0.2 3.6 3 1 1 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF78641.1 - 7.4e-05 22.9 4.6 0.0043 17.2 0.7 3.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 EGF78641.1 - 0.00017 21.0 0.6 0.38 10.1 0.0 3.5 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP DUF1565 PF07602.11 EGF78641.1 - 0.077 12.3 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) PPR PF01535.20 EGF78641.1 - 0.21 11.9 1.8 2.6 8.5 0.0 3.8 5 0 0 5 5 5 0 PPR repeat PPR_long PF17177.4 EGF78642.1 - 3.1e-08 33.2 0.1 0.033 13.5 0.0 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGF78642.1 - 1.2e-07 31.5 6.3 0.51 10.7 0.3 6.1 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.6 EGF78642.1 - 1.7e-07 31.2 1.9 2.7 8.1 0.0 5.4 4 2 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF78642.1 - 0.0014 18.8 0.7 20 5.5 0.1 4.7 4 1 1 5 5 5 1 PPR repeat family NEMP PF10225.9 EGF78642.1 - 0.022 14.4 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 NEMP family RB_A PF01858.17 EGF78642.1 - 0.048 13.5 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain GxGYxYP_C PF14323.6 EGF78642.1 - 0.071 13.0 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain TPR_15 PF13429.6 EGF78642.1 - 0.084 12.1 0.2 4.7 6.4 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78642.1 - 0.16 12.9 0.1 7 7.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 EGF78643.1 - 0.001 19.1 6.6 0.41 10.7 0.0 4.8 5 1 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF78643.1 - 0.001 19.2 0.3 0.51 10.6 0.0 3.6 3 1 0 3 3 3 1 PPR repeat family PPR PF01535.20 EGF78643.1 - 0.01 16.0 1.3 86 3.7 0.0 4.9 5 0 0 5 5 5 0 PPR repeat ATP13 PF12921.7 EGF78643.1 - 0.024 14.5 0.3 0.22 11.4 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ATPase expression PPR_long PF17177.4 EGF78643.1 - 0.028 13.8 0.1 2.1 7.7 0.0 2.8 2 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP DUF3017 PF11222.8 EGF78643.1 - 0.07 13.4 0.4 0.16 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) TBD PF12845.7 EGF78643.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 TBD domain PPR_3 PF13812.6 EGF78644.1 - 2.2e-09 37.2 0.6 0.068 13.3 0.1 5.1 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EGF78644.1 - 1.6e-08 34.2 0.4 2e-05 24.0 0.0 3.5 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EGF78644.1 - 5.5e-05 23.3 7.7 0.33 11.2 0.1 6.1 5 2 1 6 6 6 2 PPR repeat family PPR PF01535.20 EGF78644.1 - 0.00043 20.4 9.8 1.5 9.2 0.0 6.7 9 0 0 9 9 9 2 PPR repeat RED_N PF07808.13 EGF78645.1 - 2.4e-16 60.0 0.0 6e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region RED_C PF07807.11 EGF78645.1 - 1.5e-14 54.4 4.9 1.5e-14 54.4 4.9 2.1 2 0 0 2 2 2 1 RED-like protein C-terminal region Homeodomain PF00046.29 EGF78646.1 - 1.2e-07 31.4 0.9 2.3e-07 30.5 0.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGF78646.1 - 0.025 14.5 0.2 0.064 13.2 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain MmlI PF09448.10 EGF78646.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase Sortilin-Vps10 PF15902.5 EGF78647.1 - 0 1123.8 15.1 4.5e-132 441.0 1.0 3.1 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGF78647.1 - 6.5e-105 348.8 22.7 3.3e-38 131.7 2.5 3.4 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGF78647.1 - 2.2e-13 48.0 57.4 0.34 11.1 0.1 16.0 15 0 0 15 15 15 8 BNR/Asp-box repeat PSII_BNR PF14870.6 EGF78647.1 - 1.9e-07 30.6 2.5 0.051 12.8 0.0 6.0 5 1 1 6 6 6 2 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 EGF78647.1 - 0.14 12.3 11.2 80 3.7 0.0 7.8 8 0 0 8 8 8 0 BNR-Asp box repeat F5_F8_type_C PF00754.25 EGF78647.1 - 0.69 10.0 8.3 18 5.4 0.0 6.1 7 0 0 7 7 7 0 F5/8 type C domain Acetyltransf_1 PF00583.25 EGF78648.1 - 6.3e-10 39.3 0.0 7.3e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF78648.1 - 2.8e-09 37.3 0.0 3.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGF78648.1 - 3.9e-08 33.3 0.0 4.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF78648.1 - 0.03 14.3 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein UPF0121 PF03661.13 EGF78649.1 - 8.7e-66 221.8 8.9 1.1e-65 221.4 8.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) NTP_transf_6 PF06042.11 EGF78649.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase DHHC PF01529.20 EGF78649.1 - 1 9.4 7.3 0.84 9.7 3.4 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase Condensation PF00668.20 EGF78650.1 - 0.079 11.6 0.0 0.2 10.3 0.0 1.6 2 0 0 2 2 2 0 Condensation domain SAP30_Sin3_bdg PF13867.6 EGF78651.1 - 7e-08 32.7 0.6 4.3e-07 30.2 0.3 2.0 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 AT_hook PF02178.19 EGF78651.1 - 0.021 14.7 3.5 0.035 14.0 3.5 1.4 1 0 0 1 1 1 0 AT hook motif HECT_2 PF09814.9 EGF78653.1 - 1.8e-31 109.4 4.3 4.2e-31 108.1 4.3 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Pox_Ag35 PF03286.14 EGF78654.1 - 0.7 9.7 5.4 1.3 8.8 5.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Lipoprotein_20 PF13942.6 EGF78655.1 - 0.027 14.4 2.8 0.033 14.1 2.8 1.3 1 1 0 1 1 1 0 YfhG lipoprotein COX16 PF14138.6 EGF78655.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 HALZ PF02183.18 EGF78655.1 - 0.16 12.3 1.4 0.16 12.3 1.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper ATG16 PF08614.11 EGF78656.1 - 1.6e-06 28.5 222.6 4.8e-05 23.7 8.0 14.9 4 2 8 14 14 14 8 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EGF78656.1 - 0.00067 19.1 20.6 0.00067 19.1 20.6 9.4 2 2 4 6 6 6 2 Domain of unknown function (DUF4407) Trimer_CC PF08954.11 EGF78656.1 - 0.0017 17.8 0.2 0.0017 17.8 0.2 7.0 5 1 1 6 6 6 1 Trimerisation motif EzrA PF06160.12 EGF78656.1 - 0.0019 16.5 20.6 0.0019 16.5 20.6 7.9 4 3 1 5 5 5 1 Septation ring formation regulator, EzrA BRE1 PF08647.11 EGF78656.1 - 0.0046 17.0 5.0 0.0046 17.0 5.0 16.0 11 3 7 19 19 19 4 BRE1 E3 ubiquitin ligase SlyX PF04102.12 EGF78656.1 - 0.015 15.9 3.8 0.015 15.9 3.8 20.1 13 7 9 23 23 23 0 SlyX RF-1 PF00472.20 EGF78657.1 - 4.8e-17 62.0 0.0 5.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 EGF78657.1 - 0.0017 18.7 0.0 0.0021 18.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CRCB PF02537.15 EGF78658.1 - 5e-18 65.2 10.4 5e-18 65.2 10.4 1.5 2 0 0 2 2 2 1 CrcB-like protein, Camphor Resistance (CrcB) ADH_zinc_N PF00107.26 EGF78660.1 - 6.5e-16 58.5 1.0 1.1e-15 57.7 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGF78660.1 - 1.1e-08 34.9 0.0 6e-08 32.5 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGF78660.1 - 8.4e-08 33.3 0.1 1.9e-07 32.2 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase PEP_hydrolase PF09370.10 EGF78660.1 - 4.1e-05 22.9 0.5 6.6e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NAD_binding_10 PF13460.6 EGF78660.1 - 0.054 13.4 0.3 0.095 12.6 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Tim44 PF04280.15 EGF78661.1 - 6.2e-31 107.5 3.7 2.8e-30 105.3 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain DUF3150 PF11348.8 EGF78661.1 - 0.13 11.5 3.0 0.14 11.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) DUF2228 PF10228.9 EGF78661.1 - 0.9 9.2 6.7 0.9 9.2 1.3 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2228) 4HBT_3 PF13622.6 EGF78662.1 - 7.9e-32 111.5 5.3 3.2e-17 63.6 0.1 3.1 1 1 2 3 3 3 3 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGF78662.1 - 7.5e-21 74.4 0.0 1.4e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA thioesterase DUF1331 PF07048.11 EGF78662.1 - 0.029 14.0 0.2 0.057 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) EF-hand_6 PF13405.6 EGF78664.1 - 4.8e-12 44.8 9.0 1.8e-07 30.6 1.5 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EGF78664.1 - 1.2e-10 41.6 4.5 8.1e-06 26.2 0.2 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF78664.1 - 2.5e-10 39.2 11.4 1.5e-06 27.4 2.0 4.6 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EGF78664.1 - 6.1e-05 22.8 8.4 0.22 11.4 0.1 3.8 2 2 1 3 3 3 3 EF-hand domain pair UPF0154 PF03672.13 EGF78664.1 - 0.0031 17.5 0.0 0.63 10.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EGF78664.1 - 0.0033 18.3 0.0 0.0097 16.8 0.0 1.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EGF78664.1 - 0.0033 16.8 2.3 0.0033 16.8 2.3 2.7 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EGF78664.1 - 0.038 14.3 0.3 5.3 7.4 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain SIR2 PF02146.17 EGF78665.1 - 4.4e-46 157.0 0.0 6e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family RNA_POL_M_15KD PF02150.16 EGF78665.1 - 0.29 11.0 2.0 19 5.2 0.8 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit KH_1 PF00013.29 EGF78666.1 - 1.4e-40 136.9 9.0 1.2e-15 57.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGF78666.1 - 3.8e-10 39.5 4.9 0.014 15.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGF78666.1 - 6.5e-07 29.1 2.4 0.065 13.1 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGF78666.1 - 0.16 12.1 7.5 4.1 7.6 0.1 3.5 3 0 0 3 3 3 0 NusA-like KH domain SPX PF03105.19 EGF78666.1 - 6.3 6.6 7.7 9 6.1 7.7 1.1 1 0 0 1 1 1 0 SPX domain HSP20 PF00011.21 EGF78667.1 - 2.6e-05 24.3 0.0 7.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Rol_Rep_N PF18106.1 EGF78667.1 - 0.13 12.6 0.2 0.3 11.4 0.1 1.6 2 0 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain DUF2358 PF10184.9 EGF78668.1 - 2.4e-12 47.1 0.2 8.6e-09 35.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 EGF78668.1 - 0.014 14.6 0.3 0.42 9.7 0.0 2.9 3 1 1 4 4 4 0 Mitochondrial protein up-regulated during meiosis Aminotran_1_2 PF00155.21 EGF78669.1 - 4.5e-85 286.0 0.0 5.1e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Asp PF00026.23 EGF78672.1 - 3e-12 46.6 0.5 1.1e-11 44.8 0.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78672.1 - 0.00013 21.8 0.1 0.001 18.9 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF742 PF05331.11 EGF78672.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Ribosomal_L7Ae PF01248.26 EGF78673.1 - 1.2e-26 92.3 0.0 1.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGF78673.1 - 0.00029 20.9 0.1 0.00031 20.8 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EGF78673.1 - 0.00061 19.6 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Pkinase PF00069.25 EGF78674.1 - 1.1e-52 179.0 0.0 1.7e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78674.1 - 2.8e-17 62.9 0.0 6.8e-17 61.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGF78674.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQ-loop PF04193.14 EGF78675.1 - 4.3e-18 64.8 13.1 2.2e-10 40.1 0.8 3.1 4 0 0 4 4 4 2 PQ loop repeat Alpha-amylase_C PF02806.18 EGF78676.1 - 4.5e-22 78.3 0.1 1.1e-21 77.1 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EGF78676.1 - 4.3e-14 52.6 0.1 1e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EGF78676.1 - 1.3e-11 44.7 0.2 1.1e-08 35.1 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Aminotran_1_2 PF00155.21 EGF78676.1 - 0.043 13.0 0.1 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class I and II DIOX_N PF14226.6 EGF78677.1 - 0.00066 20.4 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGF78677.1 - 0.0014 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3005 PF11448.8 EGF78678.1 - 0.15 12.1 1.9 1.9 8.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3005) ABC1 PF03109.16 EGF78679.1 - 9.8e-23 80.6 0.1 2e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGF78679.1 - 0.01 15.8 0.0 0.12 12.3 0.0 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGF78679.1 - 0.27 10.6 0.9 1.9 7.7 0.1 2.6 2 1 0 2 2 2 0 Protein kinase domain UPF0220 PF05255.11 EGF78680.1 - 6.7e-41 139.6 1.9 8.8e-41 139.2 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Ribosomal_S11 PF00411.19 EGF78681.1 - 2.3e-46 156.7 1.8 2.8e-46 156.4 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 EGF78681.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) CBM_25 PF03423.13 EGF78681.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Helicase_C PF00271.31 EGF78682.1 - 8.2e-18 64.8 0.1 1e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Steroid_dh PF02544.16 EGF78683.1 - 3.7e-38 130.9 2.5 5.9e-38 130.2 2.5 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGF78683.1 - 0.0018 17.8 1.8 0.0019 17.8 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGF78683.1 - 0.039 14.4 1.8 0.039 14.4 1.8 2.5 2 1 0 3 3 3 0 Phospholipid methyltransferase COX14 PF14880.6 EGF78683.1 - 0.1 12.4 0.4 16 5.4 0.1 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly LapA_dom PF06305.11 EGF78683.1 - 0.14 12.0 2.1 0.65 9.9 0.4 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 EGF78684.1 - 7.3e-80 268.1 0.0 8.5e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78684.1 - 1.1e-40 139.6 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGF78684.1 - 1.8e-05 24.4 0.7 3.2e-05 23.6 0.7 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGF78684.1 - 2.8e-05 23.6 0.1 0.00032 20.1 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGF78684.1 - 7.4e-05 22.8 0.1 0.0032 17.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF78684.1 - 0.0047 16.3 0.2 0.011 15.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF78684.1 - 0.0082 15.1 0.1 0.01 14.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EGF78684.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Phage_T7_Capsid PF05396.11 EGF78684.1 - 0.033 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.9 EGF78684.1 - 0.12 11.8 1.0 0.49 9.9 0.1 2.0 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL NMO PF03060.15 EGF78686.1 - 3.7e-22 79.2 3.4 6e-20 71.9 3.4 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EGF78686.1 - 4.4e-05 22.7 4.9 0.00012 21.3 4.9 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGF78686.1 - 8.7e-05 21.7 1.1 0.00043 19.4 1.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TPR_1 PF00515.28 EGF78687.1 - 1.8e-27 94.0 1.2 1.1e-08 34.5 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78687.1 - 1.3e-25 87.3 2.1 5.1e-07 29.3 0.1 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGF78687.1 - 2.7e-23 81.4 2.0 3e-07 30.0 0.0 4.8 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.6 EGF78687.1 - 2.1e-17 63.5 5.1 5.7e-08 33.3 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF78687.1 - 2.6e-17 61.5 1.2 2e-05 24.4 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF78687.1 - 9.9e-17 60.1 6.2 0.00033 20.8 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78687.1 - 6.2e-15 54.6 6.3 4.6e-05 23.9 0.1 5.4 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGF78687.1 - 7.2e-13 48.9 6.8 0.0071 16.8 1.5 4.3 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGF78687.1 - 2.8e-10 40.2 2.8 0.0092 16.1 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGF78687.1 - 1.4e-09 38.2 3.0 0.037 14.4 1.4 3.9 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF78687.1 - 3e-09 37.0 9.9 0.0085 16.4 0.2 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78687.1 - 5.2e-09 35.5 3.0 0.037 14.1 0.0 4.6 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGF78687.1 - 1.7e-06 28.3 1.7 1.2 9.9 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF78687.1 - 2.2e-05 24.6 3.8 0.0049 17.1 0.2 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EGF78687.1 - 0.0026 17.8 0.4 0.089 12.9 0.1 2.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EGF78687.1 - 0.0026 18.2 4.0 0.19 12.1 0.1 3.1 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 EGF78687.1 - 0.0029 16.9 7.1 0.67 9.1 3.3 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGF78687.1 - 0.008 16.2 0.1 1.1 9.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EGF78687.1 - 0.012 15.7 11.2 3.3 7.8 0.1 5.3 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.11 EGF78687.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF2989 PF11207.8 EGF78687.1 - 0.046 13.5 0.1 9.2 6.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_10 PF13374.6 EGF78687.1 - 0.057 13.3 10.5 0.28 11.1 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat cNMP_binding PF00027.29 EGF78688.1 - 7.8e-18 64.3 0.0 5.1e-17 61.7 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Guanylate_cyc PF00211.20 EGF78688.1 - 6.9e-07 29.1 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF_2 PF13185.6 EGF78688.1 - 0.00016 22.0 0.0 0.0036 17.6 0.0 2.5 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 EGF78688.1 - 0.022 15.1 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 0 GAF domain HTH_Tnp_Tc5 PF03221.16 EGF78688.1 - 0.048 13.7 0.2 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain SH3_1 PF00018.28 EGF78689.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF78689.1 - 5.1e-06 26.3 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF78689.1 - 0.00036 20.2 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.25 EGF78690.1 - 4.1e-49 167.3 0.0 5.2e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78690.1 - 1.6e-17 63.7 0.0 2.5e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGF78690.1 - 0.078 12.6 0.3 0.23 11.0 0.2 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 EGF78690.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGF78690.1 - 0.17 11.4 0.8 0.71 9.4 0.3 2.2 1 1 1 2 2 2 0 RIO1 family RabGAP-TBC PF00566.18 EGF78692.1 - 1.7e-13 50.7 1.6 2e-09 37.5 1.1 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain NIF PF03031.18 EGF78693.1 - 4.4e-10 39.6 0.0 5.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SAPS PF04499.15 EGF78694.1 - 1.8e-82 277.7 10.7 3.1e-48 164.8 0.1 3.0 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein KIX_2 PF16987.5 EGF78695.1 - 6.7e-14 51.7 0.1 6.7e-14 51.7 0.1 3.3 3 0 0 3 3 3 1 KIX domain KIX PF02172.16 EGF78695.1 - 0.0014 18.9 0.0 0.0045 17.2 0.0 1.9 2 0 0 2 2 2 1 KIX domain DUF1411 PF07199.11 EGF78696.1 - 0.00078 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1411) Aminotran_5 PF00266.19 EGF78697.1 - 4.3e-94 315.5 0.0 5.5e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGF78697.1 - 4.8e-07 29.3 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGF78697.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGF78697.1 - 1.2e-05 24.8 0.2 2.5e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EGF78697.1 - 0.00097 18.0 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EGF78697.1 - 0.033 12.7 0.0 0.06 11.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MIS13 PF08202.11 EGF78698.1 - 1.1e-41 143.1 2.1 1.3e-41 142.8 2.1 1.0 1 0 0 1 1 1 1 Mis12-Mtw1 protein family AphA_like PF14557.6 EGF78698.1 - 0.07 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator DUF1713 PF08213.11 EGF78699.1 - 0.00044 20.1 21.0 0.00044 20.1 21.0 1.9 1 1 1 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) DUF2805 PF10985.8 EGF78699.1 - 1 9.8 9.0 1.7 9.0 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Sel1 PF08238.12 EGF78700.1 - 9.2e-36 121.5 21.9 5.7e-09 36.4 1.1 5.1 5 0 0 5 5 5 5 Sel1 repeat TPR_6 PF13174.6 EGF78700.1 - 0.19 12.4 7.4 15 6.5 0.2 4.5 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF78700.1 - 0.53 10.8 4.2 2.8 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF78700.1 - 2.5 8.8 12.2 5.2 7.8 0.8 3.5 3 2 0 3 3 3 0 Tetratricopeptide repeat SH3_9 PF14604.6 EGF78701.1 - 8.9e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF78701.1 - 9.3e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Polysacc_deac_1 PF01522.21 EGF78702.1 - 1.6e-20 73.2 0.0 2.7e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGF78702.1 - 1.2e-16 60.9 40.7 3.7e-07 30.5 11.7 3.4 2 1 1 3 3 3 3 Chitin recognition protein Epiglycanin_TR PF05647.11 EGF78703.1 - 0.001 19.0 20.9 0.001 19.0 20.9 2.3 3 1 0 3 3 3 1 Tandem-repeating region of mucin, epiglycanin-like DUF5568 PF17724.1 EGF78703.1 - 0.034 13.9 0.9 0.072 12.9 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5568) bZIP_Maf PF03131.17 EGF78704.1 - 0.027 15.0 3.4 0.033 14.7 0.1 2.0 1 1 0 2 2 2 0 bZIP Maf transcription factor 2_5_RNA_ligase2 PF13563.6 EGF78704.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily AAA_27 PF13514.6 EGF78705.1 - 0.18 11.4 0.9 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain SPAM PF02090.15 EGF78705.1 - 0.18 11.6 5.1 0.63 9.9 5.1 1.7 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF4407 PF14362.6 EGF78705.1 - 0.19 11.1 0.2 0.24 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 EGF78705.1 - 0.87 9.6 10.8 1.7 8.6 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4246 PF14033.6 EGF78706.1 - 6e-84 282.8 0.0 7.7e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HSP20 PF00011.21 EGF78708.1 - 2.8e-05 24.2 0.0 7.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Arrestin_C PF02752.22 EGF78708.1 - 0.037 14.5 0.2 0.048 14.1 0.2 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain polyprenyl_synt PF00348.17 EGF78709.1 - 5.1e-91 304.3 0.0 6.2e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DIOX_N PF14226.6 EGF78710.1 - 4.7e-06 27.4 0.0 1e-05 26.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal hDGE_amylase PF14701.6 EGF78710.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Indigoidine_A PF04227.12 EGF78711.1 - 8.8e-129 429.0 0.1 1e-128 428.8 0.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein ABC_tran PF00005.27 EGF78712.1 - 4.4e-29 101.7 0.0 1.1e-28 100.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF78712.1 - 5.5e-16 59.2 0.7 2e-09 37.7 0.0 4.0 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGF78712.1 - 4e-14 52.5 18.5 4e-14 52.5 18.5 2.7 3 0 0 3 3 3 1 ABC-2 family transporter protein SMC_N PF02463.19 EGF78712.1 - 7.9e-06 25.5 0.1 0.00025 20.5 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGF78712.1 - 0.0021 18.2 0.0 0.04 14.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EGF78712.1 - 0.039 14.4 0.9 0.087 13.3 0.9 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGF78712.1 - 0.054 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_gene1 PF09527.10 EGF78712.1 - 9.6 6.5 12.3 24 5.2 0.0 3.6 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Ferric_reduct PF01794.19 EGF78713.1 - 9.4e-22 77.5 10.7 2.7e-21 76.0 10.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGF78713.1 - 9.3e-19 68.1 0.1 3e-16 59.9 0.1 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGF78713.1 - 3.3e-13 49.7 0.0 9.4e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EGF78713.1 - 3.8e-07 30.7 0.0 8.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain BTB_2 PF02214.22 EGF78714.1 - 1.9e-08 34.5 0.1 9.1e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain CBP_BcsR PF10945.8 EGF78714.1 - 0.099 12.1 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Lectin_leg-like PF03388.13 EGF78715.1 - 1.6e-72 243.6 0.2 2.1e-72 243.2 0.2 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGF78715.1 - 4.6e-10 39.8 1.5 4.6e-10 39.8 1.5 1.4 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 EGF78715.1 - 5.4e-07 29.4 0.1 1.5e-05 24.7 0.1 2.1 1 1 0 1 1 1 1 Legume lectin domain FeoB_associated PF12669.7 EGF78715.1 - 0.084 13.3 2.1 0.2 12.1 2.1 1.6 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4366 PF14283.6 EGF78715.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2749 PF10907.8 EGF78715.1 - 0.19 11.9 0.4 0.45 10.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) NYD-SP28 PF14772.6 EGF78716.1 - 4.6e-23 81.2 7.7 4.6e-23 81.2 7.7 6.1 6 1 0 7 7 7 1 Sperm tail NYD-SP28_assoc PF14775.6 EGF78716.1 - 3.8e-20 71.7 5.2 3.8e-20 71.7 5.2 4.1 4 1 0 4 4 4 1 Sperm tail C-terminal domain DUF4358 PF14270.6 EGF78716.1 - 7.2 7.0 9.9 2.4 8.5 2.6 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Ras PF00071.22 EGF78717.1 - 3.8e-49 166.4 0.6 4.5e-49 166.2 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF78717.1 - 1.6e-17 63.8 0.0 3.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF78717.1 - 1.3e-12 47.6 0.2 1.6e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF78717.1 - 8.8e-10 38.4 0.4 2.5e-09 36.9 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF78717.1 - 7.3e-07 29.2 3.2 0.00048 20.1 0.8 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGF78717.1 - 1.5e-06 28.3 0.2 2.8e-06 27.4 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGF78717.1 - 0.00047 20.0 0.3 0.00047 20.0 0.3 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGF78717.1 - 0.0019 17.8 1.3 0.0041 16.6 1.3 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EGF78717.1 - 0.021 14.8 0.7 0.06 13.4 0.4 1.9 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_3 PF01171.20 EGF78717.1 - 0.034 13.9 0.2 0.072 12.8 0.1 1.6 1 1 0 1 1 1 0 PP-loop family ROS_MUCR PF05443.11 EGF78717.1 - 0.048 13.7 0.1 0.14 12.2 0.0 1.8 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein CENP-M PF11111.8 EGF78717.1 - 0.073 12.3 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Ima1_N PF09779.9 EGF78718.1 - 2.2e-12 48.0 1.8 3.7e-12 47.3 0.1 2.2 2 0 0 2 2 2 1 Ima1 N-terminal domain CENP_C_N PF15622.6 EGF78718.1 - 0.012 15.1 4.4 0.012 15.1 4.4 2.0 3 0 0 3 3 3 0 Kinetochore assembly subunit CENP-C N-terminal EIF_2_alpha PF07541.12 EGF78719.1 - 1.1e-38 131.9 0.0 2.4e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGF78719.1 - 2.6e-14 53.3 0.6 4.6e-14 52.5 0.6 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 EGF78719.1 - 0.011 15.1 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Amidohydrolase family Spindle_Spc25 PF08234.12 EGF78719.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 RNase_T PF00929.24 EGF78720.1 - 7.6e-25 88.4 0.0 1.3e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease HTH_AraC PF00165.23 EGF78720.1 - 0.12 12.5 0.1 4.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4168 PF13767.6 EGF78721.1 - 0.1 13.8 0.5 17 6.7 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) DUF4602 PF15375.6 EGF78722.1 - 2.6e-25 89.3 8.4 5.6e-25 88.2 8.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) S4 PF01479.25 EGF78723.1 - 1.2e-11 44.2 0.2 3.3e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EGF78723.1 - 5.5e-10 40.0 0.4 9.4e-10 39.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Rogdi_lz PF10259.9 EGF78724.1 - 3.5e-21 75.9 0.2 4.1e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein UQ_con PF00179.26 EGF78725.1 - 3.6e-49 166.0 0.0 4.1e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGF78725.1 - 6.2e-05 22.7 0.0 6.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B CBFD_NFYB_HMF PF00808.23 EGF78726.1 - 2.7e-15 56.4 0.0 4.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGF78726.1 - 0.00077 19.8 0.1 0.00077 19.8 0.1 2.3 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGF78726.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold ALMT PF11744.8 EGF78726.1 - 0.026 13.4 2.4 0.029 13.2 2.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter MAS20 PF02064.15 EGF78726.1 - 1.5 9.0 8.1 5.2 7.2 7.6 2.0 1 1 1 2 2 2 0 MAS20 protein import receptor BSP_II PF05432.11 EGF78726.1 - 1.9 8.1 13.3 0.072 12.8 7.5 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) AAA_6 PF12774.7 EGF78727.1 - 1.9e-130 434.6 0.2 1.5e-128 428.4 0.0 3.4 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGF78727.1 - 6.2e-107 358.6 24.2 6.6e-107 358.5 16.6 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGF78727.1 - 1.3e-96 324.1 7.9 1.3e-96 324.1 7.9 4.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGF78727.1 - 1.2e-70 237.1 0.1 1.2e-70 237.1 0.1 3.7 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGF78727.1 - 2.5e-60 204.0 0.0 3.1e-59 200.4 0.0 2.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 EGF78727.1 - 2.7e-47 161.5 4.9 5.6e-47 160.4 4.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EGF78727.1 - 1.4e-42 145.2 0.0 4.6e-35 120.8 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 EGF78727.1 - 2e-40 139.0 1.1 4.6e-40 137.8 0.1 2.2 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 EGF78727.1 - 1e-30 106.5 0.0 7.2e-13 48.7 0.0 6.0 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 EGF78727.1 - 3.3e-30 105.1 0.0 1.1e-29 103.4 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGF78727.1 - 9e-25 87.1 0.1 8.1e-23 80.8 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGF78727.1 - 1.1e-19 70.8 1.9 1.2e-18 67.4 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGF78727.1 - 1.1e-17 64.6 0.0 0.0028 17.9 0.0 6.3 5 0 0 5 5 5 3 AAA domain AAA PF00004.29 EGF78727.1 - 1.6e-11 44.7 0.0 0.029 14.8 0.0 5.4 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF78727.1 - 1.1e-08 35.7 5.9 0.18 12.2 0.1 6.8 6 1 1 7 7 5 2 AAA ATPase domain AAA_18 PF13238.6 EGF78727.1 - 3.3e-08 34.1 0.7 0.25 11.9 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.6 EGF78727.1 - 2.6e-07 30.7 0.3 0.38 10.8 0.0 5.5 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.6 EGF78727.1 - 2e-06 28.0 0.3 3.1 7.9 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_lid_1 PF17857.1 EGF78727.1 - 6.7e-06 26.2 0.7 0.00058 20.0 0.0 3.7 3 0 0 3 3 2 1 AAA+ lid domain AAA_19 PF13245.6 EGF78727.1 - 7.1e-06 26.4 1.0 0.17 12.3 0.0 5.4 5 0 0 5 5 5 1 AAA domain T2SSE PF00437.20 EGF78727.1 - 7.3e-06 25.2 0.2 0.31 10.1 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein ABC_tran PF00005.27 EGF78727.1 - 9.2e-06 26.2 0.6 0.42 11.1 0.0 4.9 4 0 0 4 4 3 1 ABC transporter AAA_29 PF13555.6 EGF78727.1 - 1.5e-05 24.6 0.1 0.31 10.8 0.1 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EGF78727.1 - 3.9e-05 23.5 1.3 13 5.5 0.0 5.1 5 0 0 5 5 5 0 AAA domain Mg_chelatase PF01078.21 EGF78727.1 - 6.4e-05 22.4 0.1 1.6 8.1 0.0 3.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGF78727.1 - 0.00017 21.4 0.1 0.62 9.8 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 EGF78727.1 - 0.0013 18.3 0.0 0.04 13.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EGF78727.1 - 0.0016 18.2 0.0 0.85 9.3 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain Rad17 PF03215.15 EGF78727.1 - 0.0016 18.4 0.0 31 4.4 0.0 4.4 3 0 0 3 3 3 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGF78727.1 - 0.002 18.5 0.0 1.6 9.1 0.0 4.3 4 0 0 4 4 4 1 RNA helicase AAA_28 PF13521.6 EGF78727.1 - 0.0043 17.3 0.0 8.4 6.6 0.0 4.6 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EGF78727.1 - 0.0045 16.9 0.1 25 4.7 0.0 4.5 3 0 0 3 3 3 0 NACHT domain FtsK_SpoIIIE PF01580.18 EGF78727.1 - 0.0064 15.9 0.0 0.66 9.3 0.0 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_24 PF13479.6 EGF78727.1 - 0.0068 16.2 0.5 46 3.6 0.1 4.6 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 EGF78727.1 - 0.013 15.3 0.2 6.1 6.5 0.1 3.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rpn9_C PF18261.1 EGF78727.1 - 0.035 13.7 0.2 0.15 11.6 0.2 2.1 1 0 0 1 1 1 0 Rpn9 C-terminal helix RuvB_N PF05496.12 EGF78727.1 - 0.097 12.4 0.1 4.7 6.9 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Rh5 PF18515.1 EGF78727.1 - 0.12 11.7 5.5 0.038 13.3 1.0 2.4 2 0 0 2 2 2 0 Rh5 coiled-coil domain WXG100 PF06013.12 EGF78727.1 - 0.3 11.3 2.5 11 6.3 0.6 3.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4184 PF13803.6 EGF78729.1 - 0.034 13.8 0.3 0.034 13.8 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4184) DUF2427 PF10348.9 EGF78729.1 - 0.15 11.9 4.9 0.47 10.3 4.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) DUF1129 PF06570.11 EGF78729.1 - 0.34 10.4 4.5 0.42 10.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PKcGMP_CC PF16808.5 EGF78731.1 - 0.014 15.3 11.1 0.45 10.4 0.6 5.1 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase G-gamma PF00631.22 EGF78731.1 - 0.068 13.2 2.6 0.12 12.4 0.1 2.8 2 0 0 2 2 2 0 GGL domain zf-C2H2 PF00096.26 EGF78732.1 - 5.1e-07 29.8 14.6 0.00022 21.5 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF78732.1 - 8.6e-07 29.1 8.1 0.0001 22.5 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF78732.1 - 3.6e-05 24.3 13.4 0.0049 17.6 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGF78732.1 - 0.022 14.8 2.0 0.022 14.8 2.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger SRPRB PF09439.10 EGF78733.1 - 2.1e-40 138.1 0.0 2.8e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGF78733.1 - 5.6e-14 52.0 0.0 7.8e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF78733.1 - 1.3e-06 28.4 0.0 3e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF78733.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGF78733.1 - 0.00018 21.1 0.0 0.0011 18.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGF78733.1 - 0.0039 17.0 0.8 0.33 10.7 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGF78733.1 - 0.0042 16.6 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 EGF78733.1 - 0.0053 17.0 0.0 0.013 15.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGF78733.1 - 0.008 16.1 0.5 0.032 14.1 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGF78733.1 - 0.019 15.3 0.9 0.041 14.3 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGF78733.1 - 0.021 14.7 0.3 0.17 11.8 0.1 2.1 1 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGF78733.1 - 0.023 15.2 0.4 0.033 14.7 0.2 1.8 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 EGF78733.1 - 0.051 12.6 0.1 0.1 11.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGF78733.1 - 0.057 13.2 0.4 0.15 11.9 0.2 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 EGF78733.1 - 0.071 12.7 0.0 0.09 12.4 0.0 1.4 1 1 0 1 1 1 0 Ras family ATPase_2 PF01637.18 EGF78733.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EGF78733.1 - 0.092 12.3 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGF78733.1 - 0.13 12.7 0.1 0.29 11.6 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF78733.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Polyketide_cyc PF03364.20 EGF78735.1 - 0.00048 20.3 0.4 0.001 19.3 0.4 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EGF78735.1 - 0.046 14.0 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Proteasome PF00227.26 EGF78736.1 - 3.5e-51 173.4 0.2 4.6e-51 173.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGF78736.1 - 5.5e-09 35.3 0.0 5.5e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Lon_C PF05362.13 EGF78737.1 - 2.5e-77 259.0 0.9 3.9e-77 258.4 0.4 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGF78737.1 - 1.6e-22 80.4 0.0 3e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EGF78737.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EGF78737.1 - 4.6e-08 33.2 0.0 1.6e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGF78737.1 - 2.2e-05 24.7 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) LON_substr_bdg PF02190.16 EGF78737.1 - 2.4e-05 24.3 0.3 5.3e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_22 PF13401.6 EGF78737.1 - 0.00013 22.3 0.1 0.014 15.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGF78737.1 - 0.00025 20.9 0.0 0.00093 19.1 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 EGF78737.1 - 0.0005 19.1 0.0 0.0008 18.4 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain RsgA_GTPase PF03193.16 EGF78737.1 - 0.00055 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 EGF78737.1 - 0.00069 19.4 0.1 0.0029 17.4 0.0 2.0 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGF78737.1 - 0.0015 18.3 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGF78737.1 - 0.0024 18.4 0.4 0.028 15.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGF78737.1 - 0.0027 18.1 3.1 0.0038 17.6 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 EGF78737.1 - 0.026 15.0 6.3 0.5 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF78737.1 - 0.031 14.7 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EGF78737.1 - 0.037 14.1 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGF78737.1 - 0.05 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 EGF78737.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGF78737.1 - 0.097 12.6 0.1 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EGF78737.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EGF78737.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase Mob1_phocein PF03637.17 EGF78738.1 - 3e-63 212.8 1.4 3.4e-63 212.7 1.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family SLD5_C PF16922.5 EGF78739.1 - 4.6e-05 23.5 0.0 9.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGF78739.1 - 0.00083 19.8 0.1 0.0016 18.9 0.1 1.7 1 1 0 1 1 1 1 GINS complex protein MAS20 PF02064.15 EGF78740.1 - 2.6e-32 111.6 0.1 3.4e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor SprT-like PF10263.9 EGF78741.1 - 2.2e-26 91.9 0.8 5.1e-26 90.7 0.8 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EGF78741.1 - 7.5e-08 32.2 4.3 2.3e-07 30.6 4.3 1.9 1 0 0 1 1 1 1 SprT-like zinc ribbon domain RRM_1 PF00076.22 EGF78742.1 - 1.3e-14 53.7 0.1 2.1e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5531 PF17671.1 EGF78744.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Bromodomain PF00439.25 EGF78745.1 - 2.1e-21 75.8 0.2 2.3e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Bromodomain DUF5582 PF17819.1 EGF78746.1 - 2.9e-08 34.3 0.2 4.1e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) EF-hand_1 PF00036.32 EGF78746.1 - 0.0062 16.0 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGF78746.1 - 0.0065 16.9 0.0 0.012 16.1 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair DUF5586 PF17824.1 EGF78746.1 - 0.012 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF-hand_6 PF13405.6 EGF78746.1 - 0.036 14.0 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain MgtC PF02308.16 EGF78747.1 - 0.075 13.4 0.6 0.43 11.0 0.1 2.3 2 0 0 2 2 2 0 MgtC family DUF3325 PF11804.8 EGF78747.1 - 4.1 7.6 7.5 2.7 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) Alpha_kinase PF02816.18 EGF78748.1 - 2.6e-46 158.1 0.3 3e-46 157.8 0.3 1.1 1 0 0 1 1 1 1 Alpha-kinase family PB1 PF00564.24 EGF78752.1 - 0.02 14.8 0.1 0.074 13.0 0.0 2.0 1 1 0 2 2 2 0 PB1 domain TPR_1 PF00515.28 EGF78753.1 - 5.2e-24 83.0 11.2 0.0047 16.7 0.0 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGF78753.1 - 1.5e-23 81.0 11.6 0.033 14.4 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78753.1 - 4.6e-23 79.4 21.3 0.023 14.8 0.0 11.4 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGF78753.1 - 7.3e-21 74.4 17.2 1.4e-05 25.5 1.6 7.7 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGF78753.1 - 1.4e-15 57.3 15.8 6.1e-05 23.2 0.2 8.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78753.1 - 3.6e-15 55.4 14.4 0.013 16.3 0.0 9.0 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGF78753.1 - 4e-14 52.0 12.5 4.6e-05 23.0 0.3 7.3 6 1 1 7 7 7 3 TPR repeat TPR_16 PF13432.6 EGF78753.1 - 9.2e-14 51.8 14.2 0.00015 22.4 0.1 5.5 6 1 1 7 7 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78753.1 - 2.2e-13 49.2 13.5 0.12 12.5 0.0 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGF78753.1 - 2.2e-10 40.5 10.4 3.3 8.6 0.0 10.0 10 1 1 11 11 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF78753.1 - 5.3e-09 36.2 6.8 0.082 13.1 0.1 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGF78753.1 - 7.6e-09 35.8 3.5 0.039 14.3 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF78753.1 - 1.4e-08 34.6 5.3 0.034 14.5 0.4 8.9 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGF78753.1 - 7.2e-08 32.0 13.6 0.00042 19.6 3.7 4.2 4 2 2 6 6 6 3 Tetratricopeptide repeat BTAD PF03704.17 EGF78753.1 - 8.4e-08 32.8 4.4 0.029 14.8 0.3 3.6 2 1 1 3 3 3 3 Bacterial transcriptional activator domain TPR_9 PF13371.6 EGF78753.1 - 4.9e-07 29.8 11.0 0.0096 16.0 0.4 5.4 2 1 3 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.8 EGF78753.1 - 1.5e-05 24.1 3.4 0.25 10.2 0.0 3.9 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 EGF78753.1 - 0.00011 22.6 3.8 0.2 12.1 0.2 3.7 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation RNase_3_N PF18497.1 EGF78753.1 - 0.023 14.9 0.2 0.11 12.7 0.2 2.2 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain PknG_TPR PF16918.5 EGF78753.1 - 0.028 13.2 0.1 0.18 10.5 0.1 2.3 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat ANAPC5 PF12862.7 EGF78753.1 - 0.048 13.7 2.8 2.1 8.5 0.1 4.6 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 EGF78753.1 - 0.052 14.2 0.2 33 5.5 0.2 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EGF78753.1 - 0.057 12.4 2.1 23 3.9 0.1 3.5 3 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Abhydrolase_1 PF00561.20 EGF78754.1 - 2.3e-14 53.7 0.0 1.1e-11 44.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF78754.1 - 9.2e-13 48.0 0.0 1.3e-09 37.7 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 EGF78754.1 - 3.4e-08 33.7 0.0 0.00092 19.2 0.0 2.9 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGF78754.1 - 1.5e-05 24.7 0.0 0.0001 21.9 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGF78754.1 - 0.00019 21.0 0.0 0.16 11.5 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EGF78754.1 - 0.00078 18.2 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EGF78754.1 - 0.0014 19.3 0.0 0.03 14.9 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGF78754.1 - 0.0025 17.7 0.0 0.38 10.5 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EGF78754.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGF78754.1 - 0.0091 15.7 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase DUF818 PF05677.12 EGF78754.1 - 0.015 14.2 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PAF-AH_p_II PF03403.13 EGF78754.1 - 0.034 12.7 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 EGF78754.1 - 0.038 13.8 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.13 EGF78754.1 - 0.038 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 EGF78754.1 - 0.047 13.2 0.0 0.6 9.6 0.0 2.1 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 EGF78754.1 - 0.061 12.9 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PTPlike_phytase PF14566.6 EGF78755.1 - 2.7e-133 440.1 0.4 4.5e-47 160.1 0.1 4.3 3 1 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 EGF78755.1 - 4.4e-08 33.0 0.0 0.23 11.3 0.0 3.6 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF78755.1 - 0.00011 21.8 0.8 2.2 7.8 0.0 3.3 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGF78755.1 - 0.011 15.8 0.0 2.7 7.9 0.0 3.4 4 0 0 4 4 4 0 Tyrosine phosphatase family BRK PF07533.16 EGF78755.1 - 0.14 11.8 2.0 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 BRK domain UQ_con PF00179.26 EGF78757.1 - 1.1e-11 44.5 0.0 1.4e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Carn_acyltransf PF00755.20 EGF78758.1 - 2e-199 664.1 0.2 2.2e-199 663.9 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PX PF00787.24 EGF78759.1 - 1.7e-26 92.4 0.6 2.5e-25 88.6 0.1 2.5 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGF78759.1 - 2.7e-19 69.7 5.9 1.6e-16 60.6 5.9 2.3 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.18 EGF78759.1 - 0.00065 19.4 5.6 0.0068 16.1 5.6 2.3 1 1 0 1 1 1 1 BAR domain GrpE PF01025.19 EGF78759.1 - 0.0051 16.5 1.6 0.029 14.0 0.3 2.4 2 0 0 2 2 2 1 GrpE BAR_3_WASP_bdg PF10456.9 EGF78759.1 - 0.007 15.9 4.2 0.052 13.0 0.6 2.5 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein FAM92 PF06730.11 EGF78759.1 - 0.012 15.0 1.6 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 FAM92 protein BAR_3 PF16746.5 EGF78759.1 - 0.026 14.2 3.4 0.21 11.3 0.0 3.0 2 1 1 4 4 4 0 BAR domain of APPL family AAA_assoc_C PF09821.9 EGF78759.1 - 0.51 10.9 3.1 7.5 7.1 0.1 2.7 3 0 0 3 3 3 0 C-terminal AAA-associated domain Xpo1 PF08389.12 EGF78761.1 - 1.3e-11 44.7 11.1 1.6e-07 31.5 0.1 3.7 3 1 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 EGF78761.1 - 0.001 18.9 0.1 0.0046 16.8 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ribosomal_L35p PF01632.19 EGF78762.1 - 0.0014 19.1 5.5 0.0014 19.1 5.5 2.2 3 0 0 3 3 3 1 Ribosomal protein L35 GFO_IDH_MocA PF01408.22 EGF78763.1 - 7.6e-11 42.9 0.5 5.1e-10 40.2 0.5 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF5352 PF17303.2 EGF78763.1 - 0.053 13.4 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5352) Guanylate_cyc_2 PF09778.9 EGF78764.1 - 1.1e-67 227.5 2.2 1.2e-67 227.4 2.2 1.0 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 EGF78764.1 - 1.2e-06 29.1 0.6 1.3e-05 25.8 0.6 2.1 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EGF78764.1 - 0.00068 19.6 0.1 0.048 13.6 0.0 2.3 2 0 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 BtrH_N PF14399.6 EGF78764.1 - 0.085 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Peptidase_C39 PF03412.15 EGF78764.1 - 0.11 12.3 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase C39 family Snf7 PF03357.21 EGF78765.1 - 2e-28 99.1 20.9 2.3e-28 99.0 20.9 1.0 1 0 0 1 1 1 1 Snf7 PIG-S PF10510.9 EGF78765.1 - 0.052 12.4 5.5 0.059 12.2 5.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein MciZ PF13072.6 EGF78765.1 - 0.16 11.8 0.6 0.43 10.5 0.6 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Kinesin_assoc PF16183.5 EGF78765.1 - 0.16 12.1 4.0 0.2 11.8 4.0 1.2 1 0 0 1 1 1 0 Kinesin-associated V-SNARE_C PF12352.8 EGF78765.1 - 0.21 11.9 5.4 6.3 7.2 0.2 2.8 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus H-kinase_dim PF02895.14 EGF78765.1 - 2.3 8.7 8.0 5.7 7.4 5.9 2.7 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain RCC1 PF00415.18 EGF78766.1 - 2.6e-26 92.0 12.0 1.2e-06 29.1 0.1 7.7 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF78766.1 - 4.2e-14 51.9 25.3 0.00011 21.9 0.2 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 EGF78766.1 - 0.049 13.8 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Nup214_FG PF18617.1 EGF78766.1 - 0.33 11.5 3.8 5.8 7.5 0.5 3.0 2 0 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain MHYT PF03707.16 EGF78767.1 - 1.1e-24 86.3 34.1 2.8e-10 40.2 8.2 4.9 4 1 0 4 4 4 4 Bacterial signalling protein N terminal repeat zf-RING_2 PF13639.6 EGF78768.1 - 2e-09 37.6 21.9 4.3e-05 23.7 4.4 3.1 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EGF78768.1 - 7.2e-09 35.5 21.0 1.9e-05 24.5 3.6 3.1 3 1 1 4 4 4 2 zinc-RING finger domain zf-rbx1 PF12678.7 EGF78768.1 - 1.3e-08 35.0 16.9 0.0004 20.6 3.2 3.0 2 1 1 3 3 3 2 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGF78768.1 - 1.5e-07 31.4 11.0 0.0017 18.4 3.5 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGF78768.1 - 1.9e-07 30.8 10.4 0.0012 18.6 2.3 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF78768.1 - 9.7e-07 28.4 11.3 0.0043 16.8 0.8 3.9 3 0 0 3 3 3 2 RING-like zinc finger IQ PF00612.27 EGF78768.1 - 2.1e-05 23.9 3.1 2.1e-05 23.9 3.1 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif Prok-RING_4 PF14447.6 EGF78768.1 - 2.1e-05 24.3 17.6 0.0014 18.5 3.2 2.7 3 0 0 3 3 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF78768.1 - 3.5e-05 23.7 15.5 0.0045 17.0 2.4 4.1 3 1 1 4 4 4 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF78768.1 - 0.00067 19.5 22.4 0.0036 17.1 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGF78768.1 - 0.081 12.7 0.6 0.081 12.7 0.6 3.4 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain Trm112p PF03966.16 EGF78768.1 - 0.093 13.3 0.6 1.4 9.5 0.6 2.4 1 1 0 1 1 1 0 Trm112p-like protein zf-C3HC4_2 PF13923.6 EGF78768.1 - 0.66 9.9 24.3 0.14 12.0 5.4 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGF78768.1 - 0.71 10.2 14.9 0.72 10.2 6.1 3.0 2 0 0 2 2 2 0 RING-like domain zf-UDP PF14569.6 EGF78768.1 - 6.7 6.9 9.9 1.1 9.4 0.5 2.8 3 0 0 3 3 3 0 Zinc-binding RING-finger WD40 PF00400.32 EGF78769.1 - 1.6e-11 44.6 14.6 0.15 13.0 0.0 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF78769.1 - 2.3e-11 43.8 0.1 1.7e-05 25.0 0.0 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGF78769.1 - 0.0047 15.3 0.1 0.019 13.3 0.0 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EGF78769.1 - 0.013 14.5 0.1 21 4.0 0.0 3.6 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sec7 PF01369.20 EGF78770.1 - 8e-70 234.2 0.7 8e-70 234.2 0.7 2.6 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGF78770.1 - 1.1e-34 119.7 1.2 1.1e-34 119.7 1.2 4.1 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGF78770.1 - 6.8e-31 106.0 1.4 6.8e-31 106.0 1.4 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGF78770.1 - 3.3e-15 56.2 11.6 2.8e-14 53.2 0.1 4.8 5 0 0 5 5 5 2 Dimerisation and cyclophilin-binding domain of Mon2 Tic110 PF16940.5 EGF78770.1 - 0.08 11.4 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter UQ_con PF00179.26 EGF78771.1 - 1.7e-18 66.6 0.0 3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1619 PF07773.11 EGF78772.1 - 1.1e-25 91.2 0.1 2.4e-24 86.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) DHHC PF01529.20 EGF78773.1 - 2.9e-31 108.3 14.9 2.9e-31 108.3 14.9 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase MgtE PF01769.16 EGF78773.1 - 0.049 14.0 4.4 0.41 11.0 0.1 2.4 2 0 0 2 2 2 0 Divalent cation transporter ADH_N PF08240.12 EGF78773.1 - 5.5 6.9 6.5 14 5.6 6.5 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Titin_Z PF09042.11 EGF78774.1 - 0.11 12.4 0.4 0.3 11.1 0.1 1.8 2 0 0 2 2 2 0 Titin Z HAT PF02184.16 EGF78775.1 - 1.6e-25 88.8 61.8 4.5e-13 48.9 1.1 13.4 14 1 0 14 14 14 8 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EGF78775.1 - 1.3e-17 63.0 23.3 5.8e-05 23.6 0.8 10.7 9 4 5 14 14 11 5 Tetratricopeptide repeat Suf PF05843.14 EGF78775.1 - 1.3e-15 58.1 21.4 6e-06 26.5 3.6 5.6 2 1 1 4 4 4 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGF78775.1 - 4.2e-12 46.4 0.2 0.00061 20.2 0.0 6.9 6 1 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78775.1 - 1.2e-08 34.5 2.2 3.7 7.9 0.1 9.2 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF78775.1 - 2.7e-08 33.6 1.2 0.018 15.4 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF78775.1 - 2.7e-07 30.3 1.9 7.4 7.1 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF78775.1 - 6.1e-05 23.4 10.2 26 5.7 0.0 9.3 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF78775.1 - 0.00089 19.9 5.8 30 5.4 0.4 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGF78775.1 - 0.006 16.7 9.7 0.039 14.1 0.4 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78775.1 - 0.016 15.2 3.5 40 4.6 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EGF78775.1 - 0.39 10.8 15.9 0.83 9.8 0.1 6.2 5 1 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 AAA_11 PF13086.6 EGF78776.1 - 0.0095 15.7 0.3 0.017 14.9 0.3 1.5 1 0 0 1 1 1 1 AAA domain DUF4820 PF16091.5 EGF78776.1 - 0.037 13.4 0.1 0.037 13.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) DUF2115 PF09888.9 EGF78776.1 - 0.15 12.6 1.8 0.25 11.8 0.6 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Ntox15 PF15604.6 EGF78776.1 - 0.17 12.0 2.2 14 5.8 0.2 2.4 2 1 0 2 2 2 0 Novel toxin 15 PSII_Pbs27 PF13326.6 EGF78776.1 - 0.21 11.9 1.7 0.47 10.8 0.3 2.0 2 0 0 2 2 2 0 Photosystem II Pbs27 DUF573 PF04504.14 EGF78776.1 - 0.55 10.9 8.4 7.8 7.2 2.6 4.0 3 2 0 4 4 4 0 Protein of unknown function, DUF573 DUF4246 PF14033.6 EGF78777.1 - 4.5e-30 105.2 0.0 5.6e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Asp PF00026.23 EGF78779.1 - 2.2e-14 53.6 0.9 4e-14 52.7 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78779.1 - 2e-07 31.0 0.5 6.5e-07 29.3 0.5 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal FAD_binding_4 PF01565.23 EGF78779.1 - 0.059 13.1 0.1 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Arm PF00514.23 EGF78780.1 - 0.00048 20.1 0.0 0.0078 16.2 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF19 PF01579.18 EGF78781.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF19) DUF713 PF05218.14 EGF78781.1 - 0.039 13.7 2.1 0.21 11.3 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF713) PAG PF15347.6 EGF78785.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Peptidase_M36 PF02128.15 EGF78788.1 - 1.9e-47 162.2 1.1 2.1e-41 142.3 0.6 2.0 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) MR_MLE_N PF02746.16 EGF78788.1 - 0.046 13.9 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Peptidase_S41 PF03572.18 EGF78789.1 - 6.4e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 MxiM PF11441.8 EGF78789.1 - 0.034 14.4 0.1 0.098 13.0 0.1 1.8 1 0 0 1 1 1 0 Pilot protein MxiM ABC_tran PF00005.27 EGF78790.1 - 3.9e-31 108.4 0.0 9.8e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF78790.1 - 3.1e-17 63.3 0.9 5.6e-11 42.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGF78790.1 - 2.2e-15 56.7 33.3 3e-15 56.2 33.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 EGF78790.1 - 0.00043 19.8 0.1 0.059 12.8 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGF78790.1 - 0.0047 16.7 0.2 0.062 13.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EGF78790.1 - 0.0047 17.5 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGF78790.1 - 0.0062 16.3 0.0 1.7 8.3 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EGF78790.1 - 0.0066 16.7 0.0 0.082 13.2 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGF78790.1 - 0.045 13.5 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 EGF78790.1 - 0.1 11.2 0.0 2.5 6.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGF78790.1 - 0.12 12.0 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 EGF78791.1 - 8.9e-23 80.9 0.0 3.2e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF78791.1 - 1.9e-15 57.2 0.0 5.6e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGF78791.1 - 5e-11 43.2 0.2 1.5e-10 41.7 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.15 EGF78791.1 - 5.6e-07 29.7 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_46 PF01374.18 EGF78792.1 - 2.7e-26 92.5 0.0 3.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Pkinase PF00069.25 EGF78793.1 - 7.3e-67 225.5 0.0 8.5e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78793.1 - 6.5e-46 156.7 0.0 7.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78793.1 - 6.6e-07 28.9 0.0 0.00042 19.7 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGF78793.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGF78793.1 - 0.043 12.9 0.1 0.069 12.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGF78793.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.13 EGF78795.1 - 1e-26 93.5 0.0 6.8e-12 45.5 0.0 2.7 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal GAS PF13851.6 EGF78795.1 - 0.092 12.1 25.9 0.097 12.0 0.2 3.6 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.12 EGF78795.1 - 0.52 10.5 4.4 21 5.3 0.1 3.8 3 0 0 3 3 3 0 MbeD/MobD like Cep57_MT_bd PF06657.13 EGF78795.1 - 1.3 9.6 13.7 2.5 8.6 0.9 4.2 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SKA2 PF16740.5 EGF78795.1 - 2.8 7.8 16.9 4.2 7.2 0.5 4.2 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 YlqD PF11068.8 EGF78795.1 - 4.2 7.8 16.0 0.55 10.6 2.7 3.0 2 1 0 2 2 2 0 YlqD protein FlxA PF14282.6 EGF78795.1 - 4.3 7.4 20.3 0.69 9.9 5.7 4.2 2 2 1 3 3 3 0 FlxA-like protein E1-E2_ATPase PF00122.20 EGF78796.1 - 4.2e-46 156.7 4.0 1.7e-45 154.7 1.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGF78796.1 - 3e-20 72.7 18.8 2.9e-15 56.4 8.4 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGF78796.1 - 1.4e-18 66.8 0.0 2.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGF78796.1 - 3.9e-18 66.5 0.0 7.5e-10 39.4 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF78796.1 - 3e-15 55.7 0.0 8.4e-15 54.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF78796.1 - 0.0026 17.5 0.4 0.067 12.9 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGF78796.1 - 0.097 13.1 0.3 3.6 7.9 0.1 3.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Collagen PF01391.18 EGF78797.1 - 0.00043 20.0 14.4 0.00078 19.2 14.4 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Sugar_tr PF00083.24 EGF78798.1 - 5.5e-53 180.4 19.8 7.6e-53 180.0 19.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF78798.1 - 3.1e-29 102.0 38.8 6.5e-27 94.4 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGF78798.1 - 1.7e-05 24.3 4.6 1.7e-05 24.3 4.6 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB V-SNARE_C PF12352.8 EGF78799.1 - 8.6e-11 42.0 0.3 8.6e-11 42.0 0.3 1.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Amidase_3 PF01520.18 EGF78799.1 - 0.034 14.2 0.5 0.055 13.6 0.5 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase SOAR PF16533.5 EGF78799.1 - 0.06 13.3 0.2 0.29 11.1 0.0 2.2 3 0 0 3 3 3 0 STIM1 Orai1-activating region DUF2470 PF10615.9 EGF78800.1 - 4.1e-09 36.9 0.0 7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EGF78800.1 - 0.0008 19.7 4.8 0.0014 18.9 4.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TTL PF03133.15 EGF78801.1 - 1.1e-73 247.9 6.6 4.5e-56 190.2 0.0 3.7 4 0 0 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGF78801.1 - 3.7e-08 32.9 0.0 0.0011 18.3 0.0 2.9 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGF78801.1 - 7.1e-05 22.2 0.0 0.065 12.5 0.0 2.7 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Ecl1 PF12855.7 EGF78802.1 - 0.00062 21.0 27.0 0.0013 20.0 27.0 1.8 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 EGF78802.1 - 0.011 16.4 2.1 0.029 15.0 2.1 1.7 1 0 0 1 1 1 0 PLATZ transcription factor Spectrin_like PF18373.1 EGF78802.1 - 0.081 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Spectrin like domain zf-MYND PF01753.18 EGF78802.1 - 0.3 11.2 3.0 0.78 9.9 3.0 1.8 1 1 0 1 1 1 0 MYND finger Peptidase_M36 PF02128.15 EGF78803.1 - 9.1e-138 459.4 3.1 1.1e-137 459.2 3.1 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF78803.1 - 5.6e-06 26.3 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain PepSY PF03413.19 EGF78803.1 - 0.095 13.3 0.1 0.23 12.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF1539 PF07560.11 EGF78804.1 - 0.00015 21.8 7.7 0.014 15.5 1.4 3.9 2 1 2 4 4 4 3 Domain of Unknown Function (DUF1539) Sec16_C PF12931.7 EGF78804.1 - 0.12 12.1 2.4 4.3 6.9 0.0 3.0 1 1 0 3 3 3 0 Sec23-binding domain of Sec16 AbiGi PF10899.8 EGF78805.1 - 0.047 13.5 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin YkyA PF10368.9 EGF78805.1 - 0.051 13.3 4.6 0.076 12.7 4.6 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4407 PF14362.6 EGF78805.1 - 0.38 10.1 1.8 0.51 9.6 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KELK PF15796.5 EGF78805.1 - 0.93 10.0 9.8 0.13 12.8 1.1 2.4 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF5578 PF17741.1 EGF78806.1 - 0.012 15.1 0.6 0.028 13.8 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5578) Adaptin_N PF01602.20 EGF78806.1 - 0.019 13.5 1.3 0.08 11.5 0.1 2.3 2 1 1 3 3 3 0 Adaptin N terminal region Arm PF00514.23 EGF78806.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat TCP PF03634.13 EGF78807.1 - 1.1 9.8 7.4 0.97 10.0 3.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor Asp PF00026.23 EGF78809.1 - 2.3e-06 27.3 0.0 1.1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78809.1 - 0.00091 19.0 0.0 0.0056 16.5 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF78809.1 - 0.04 14.5 0.1 1 10.1 0.1 2.4 2 0 0 2 2 2 0 Aspartyl protease SKA2 PF16740.5 EGF78811.1 - 0.073 12.9 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 YpjP PF14005.6 EGF78812.1 - 0.014 15.4 2.4 8.1 6.5 0.1 3.2 1 1 2 3 3 3 0 YpjP-like protein TolA_bind_tri PF16331.5 EGF78812.1 - 0.028 14.5 6.3 24 5.1 0.2 4.2 4 0 0 4 4 4 0 TolA binding protein trimerisation DUF4504 PF14953.6 EGF78812.1 - 0.037 13.4 0.2 0.84 9.0 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4504) Pox_A_type_inc PF04508.12 EGF78812.1 - 0.081 12.8 3.8 33 4.6 0.1 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PspB PF06667.12 EGF78812.1 - 0.46 10.6 1.7 99 3.1 0.0 4.0 4 0 0 4 4 4 0 Phage shock protein B Rootletin PF15035.6 EGF78812.1 - 0.76 9.8 12.9 12 5.9 3.1 3.5 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion ARGLU PF15346.6 EGF78812.1 - 1.4 8.7 9.8 1.4 8.8 7.0 2.3 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 CLZ PF16526.5 EGF78812.1 - 7.7 7.0 9.1 1e+02 3.3 0.1 4.5 5 0 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Asp PF00026.23 EGF78814.1 - 1.2e-10 41.4 0.1 2.3e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78814.1 - 7.9e-05 22.5 0.0 0.00024 20.9 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal FlaF PF07309.11 EGF78815.1 - 0.016 15.3 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 Flagellar protein FlaF DUF3381 PF11861.8 EGF78815.1 - 0.04 13.7 1.0 0.093 12.5 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4709 PF15821.5 EGF78815.1 - 0.074 13.3 0.3 8.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) SBP_bac_3 PF00497.20 EGF78815.1 - 0.078 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Peptidase_M36 PF02128.15 EGF78816.1 - 4.6e-130 434.1 1.2 5.1e-130 433.9 1.2 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF78816.1 - 0.0068 16.3 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain FH2 PF02181.23 EGF78817.1 - 1.2e-58 199.1 4.8 2.2e-58 198.2 4.8 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGF78817.1 - 2.1e-25 89.4 3.5 5.4e-25 88.0 3.5 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGF78817.1 - 8.6e-24 84.2 1.9 8.6e-24 84.2 1.9 2.6 2 1 0 2 2 2 1 Diaphanous FH3 Domain DUF5578 PF17741.1 EGF78817.1 - 0.0029 17.1 0.4 0.035 13.5 0.4 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF5578) Myb_DNA-bind_6 PF13921.6 EGF78818.1 - 0.0072 16.5 0.8 0.014 15.6 0.2 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Kre28 PF17097.5 EGF78818.1 - 0.012 14.6 0.2 0.012 14.6 0.2 1.0 1 0 0 1 1 1 0 Spindle pole body component Borrelia_lipo_1 PF05714.11 EGF78818.1 - 0.016 15.0 1.4 0.018 14.8 1.4 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein GrpE PF01025.19 EGF78818.1 - 0.021 14.5 0.4 0.023 14.4 0.4 1.0 1 0 0 1 1 1 0 GrpE Lipoprotein_7 PF01540.16 EGF78818.1 - 0.074 12.3 1.2 0.082 12.2 1.2 1.0 1 0 0 1 1 1 0 Adhesin lipoprotein BRE1 PF08647.11 EGF78819.1 - 0.013 15.5 9.1 0.65 10.1 2.6 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Prefoldin_2 PF01920.20 EGF78819.1 - 0.02 14.8 10.2 0.064 13.2 10.2 1.6 1 1 0 1 1 1 0 Prefoldin subunit GBP_C PF02841.14 EGF78819.1 - 0.025 14.0 0.4 0.025 14.0 0.4 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Snf7 PF03357.21 EGF78819.1 - 0.045 13.3 0.3 0.045 13.3 0.3 2.1 2 0 0 2 2 2 0 Snf7 HHH_7 PF14635.6 EGF78819.1 - 0.073 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif SlyX PF04102.12 EGF78819.1 - 0.12 13.0 3.2 0.17 12.6 0.1 2.1 2 0 0 2 2 2 0 SlyX Mito_fiss_reg PF05308.11 EGF78819.1 - 0.16 12.0 0.3 0.74 9.9 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator GrpE PF01025.19 EGF78819.1 - 0.2 11.3 7.6 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 GrpE DUF4407 PF14362.6 EGF78819.1 - 0.23 10.8 1.2 0.79 9.0 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YkyA PF10368.9 EGF78819.1 - 0.24 11.1 12.2 0.77 9.4 12.2 1.7 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4201 PF13870.6 EGF78819.1 - 0.25 11.1 9.7 0.41 10.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ABC_tran_CTD PF16326.5 EGF78819.1 - 0.35 11.2 6.9 5.6 7.3 0.3 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain MapZ_EC1 PF18041.1 EGF78819.1 - 0.49 10.6 7.8 2.6 8.3 0.6 2.2 2 0 0 2 2 2 0 MapZ extracellular domain 1 Seryl_tRNA_N PF02403.22 EGF78819.1 - 0.69 10.2 5.9 0.5 10.6 0.2 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 EGF78819.1 - 1.5 8.9 9.1 2.6 8.1 0.5 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 EGF78819.1 - 1.8 8.4 7.4 1.1 9.0 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 EGF78819.1 - 2.5 8.2 13.8 0.34 11.0 2.4 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nore1-SARAH PF16517.5 EGF78819.1 - 4.8 7.2 7.5 25 4.9 0.5 3.3 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain FliD_N PF02465.18 EGF78819.1 - 6 7.6 11.5 1.9 9.3 0.3 3.0 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4337 PF14235.6 EGF78819.1 - 8.5 6.5 12.3 2.9 8.0 1.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Peptidase_M36 PF02128.15 EGF78821.1 - 1.5e-138 462.0 0.4 1.7e-138 461.8 0.4 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Aa_trans PF01490.18 EGF78822.1 - 7.7e-05 21.6 20.7 7.7e-05 21.6 20.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein 4HB_MCP_1 PF12729.7 EGF78822.1 - 0.0074 15.8 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction MRVI1 PF05781.12 EGF78822.1 - 0.44 9.2 0.4 0.59 8.7 0.4 1.1 1 0 0 1 1 1 0 MRVI1 protein zf-C2HC_2 PF13913.6 EGF78823.1 - 1.8e-12 46.8 19.9 3.5e-06 26.8 0.2 5.1 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf_UBZ PF18439.1 EGF78823.1 - 0.00089 18.8 6.0 1.2 8.8 0.1 4.3 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf_C2HC_14 PF18574.1 EGF78823.1 - 0.04 13.7 6.3 2.7 7.9 1.4 2.9 2 0 0 2 2 2 0 C2HC Zing finger domain Evr1_Alr PF04777.13 EGF78823.1 - 0.046 14.2 10.8 0.24 11.9 1.6 3.6 2 1 1 3 3 3 0 Erv1 / Alr family dCMP_cyt_deam_1 PF00383.23 EGF78823.1 - 0.069 13.0 2.7 2.3 8.2 0.3 2.6 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region Sgf11 PF08209.11 EGF78823.1 - 0.094 12.3 12.2 0.45 10.1 0.1 3.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) YacG PF03884.14 EGF78823.1 - 0.12 12.1 0.8 0.34 10.7 0.8 1.8 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Nairovirus_M PF07948.11 EGF78823.1 - 0.2 9.9 1.5 0.53 8.4 0.1 2.0 2 0 0 2 2 2 0 Nairovirus M polyprotein-like APOBEC4 PF18775.1 EGF78823.1 - 0.21 11.8 0.4 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 APOBEC4 zinc_ribbon_9 PF14369.6 EGF78823.1 - 0.23 11.8 1.8 1.1 9.6 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2 PF00096.26 EGF78823.1 - 0.25 11.9 5.7 47 4.7 0.1 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-U11-48K PF05253.12 EGF78823.1 - 0.59 10.1 7.0 6.9 6.7 0.2 3.2 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger zf-C2H2_4 PF13894.6 EGF78823.1 - 9.6 7.4 19.8 7.1 7.8 0.1 4.9 5 0 0 5 5 4 0 C2H2-type zinc finger Na_Ca_ex PF01699.24 EGF78824.1 - 4.3e-34 117.6 33.4 2.4e-21 76.3 12.7 3.6 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Cation_efflux PF01545.21 EGF78824.1 - 2e-18 66.8 8.9 2e-18 66.8 8.9 4.4 4 2 1 5 5 5 2 Cation efflux family GP79 PF17463.2 EGF78824.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Gene product 79 Phage_holin_5_2 PF16079.5 EGF78824.1 - 5.1 7.5 9.6 4.2 7.8 0.8 4.0 2 1 2 4 4 4 0 Phage holin family Hol44, in holin superfamily V zf-RING_2 PF13639.6 EGF78825.1 - 7.5e-12 45.4 6.9 1.3e-11 44.6 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF78825.1 - 1e-08 34.9 7.5 1.8e-08 34.1 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF78825.1 - 2.9e-08 33.9 5.0 5.7e-08 32.9 5.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF78825.1 - 3.5e-06 26.8 5.1 6.9e-06 25.8 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF78825.1 - 5.2e-06 26.1 6.8 5.2e-06 26.1 6.8 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGF78825.1 - 0.0012 18.7 3.8 0.0026 17.6 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF78825.1 - 0.0015 18.4 4.6 0.0026 17.7 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF78825.1 - 0.002 18.1 2.1 0.004 17.2 0.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGF78825.1 - 0.0086 16.1 4.8 0.024 14.7 4.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGF78825.1 - 0.01 15.7 5.2 0.019 14.8 5.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGF78825.1 - 0.012 15.8 6.0 0.058 13.6 6.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2547 PF10818.8 EGF78825.1 - 0.049 14.6 1.2 0.3 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Bunya_RdRp PF04196.12 EGF78825.1 - 0.11 10.8 0.2 0.16 10.3 0.2 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase zf-RING_10 PF16685.5 EGF78825.1 - 0.85 9.8 3.8 1.5 9.0 3.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 EGF78825.1 - 1.3 9.2 5.5 2.7 8.2 5.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 EGF78826.1 - 1.1e-06 28.9 10.6 1.1e-06 28.9 10.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGF78826.1 - 0.0014 18.5 11.9 0.0014 18.5 11.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGF78826.1 - 0.02 14.6 11.4 0.02 14.6 11.4 2.0 2 0 0 2 2 2 0 RING-like zinc finger Pkinase PF00069.25 EGF78827.1 - 5e-60 203.1 0.0 7.6e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78827.1 - 3.1e-33 115.2 0.1 4.7e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78827.1 - 4.1e-07 29.6 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF78827.1 - 0.0036 17.3 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF78827.1 - 0.016 14.8 0.5 0.039 13.5 0.1 1.8 2 0 0 2 2 2 0 RIO1 family NAF PF03822.14 EGF78827.1 - 0.073 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 NAF domain Asp PF00026.23 EGF78829.1 - 2.6e-92 309.6 0.8 3e-92 309.4 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78829.1 - 2.1e-15 57.4 1.4 1.1e-13 51.8 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGF78829.1 - 0.12 13.0 0.4 6.6 7.5 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease IstB_IS21 PF01695.17 EGF78830.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Polysacc_deac_1 PF01522.21 EGF78832.1 - 8.6e-26 90.3 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 EGF78832.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Virulence protein nec1 CwfJ_C_2 PF04676.14 EGF78833.1 - 1.3e-32 112.6 1.0 1.3e-32 112.6 1.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EGF78833.1 - 9.3e-32 109.5 0.2 1.7e-31 108.6 0.2 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Strabismus PF06638.11 EGF78833.1 - 0.32 9.6 5.5 0.68 8.5 5.5 1.5 1 0 0 1 1 1 0 Strabismus protein PPR_2 PF13041.6 EGF78835.1 - 3.8e-07 30.2 0.8 0.0017 18.5 0.0 3.9 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EGF78835.1 - 0.0024 17.9 0.2 0.026 14.6 0.0 2.6 2 1 1 3 3 3 1 Pentatricopeptide repeat domain DUF3368 PF11848.8 EGF78835.1 - 0.0044 16.8 0.1 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) PPR PF01535.20 EGF78835.1 - 0.0066 16.6 0.1 4.3 7.8 0.0 3.8 3 0 0 3 3 3 1 PPR repeat Dynactin PF12455.8 EGF78835.1 - 0.054 12.7 1.0 0.098 11.9 1.0 1.3 1 0 0 1 1 1 0 Dynein associated protein DUF885 PF05960.11 EGF78837.1 - 1.5e-119 401.1 0.0 1.7e-119 400.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Y_phosphatase2 PF03162.13 EGF78839.1 - 2.5e-32 111.7 0.0 2.9e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2434 PF10361.9 EGF78840.1 - 0.074 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Ribosomal_L5_C PF00673.21 EGF78841.1 - 7.3e-22 77.4 0.0 1.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGF78841.1 - 1.4e-20 73.3 0.0 9e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Cyto_heme_lyase PF01265.17 EGF78842.1 - 1.1e-63 215.6 8.9 1.2e-62 212.1 8.9 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase JAB PF01398.21 EGF78843.1 - 1.8e-15 56.9 0.0 3.8e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGF78843.1 - 1.8e-07 31.0 0.0 4.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CUE PF02845.16 EGF78844.1 - 1.8e-09 37.1 0.2 4.3e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 CUE domain RAP80_UIM PF18282.1 EGF78844.1 - 2.7 7.8 7.1 1.1 9.1 3.1 2.2 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Asp PF00026.23 EGF78845.1 - 2.6e-92 309.6 0.8 3e-92 309.4 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF78845.1 - 2.1e-15 57.4 1.4 1.1e-13 51.8 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGF78845.1 - 0.12 13.0 0.4 6.6 7.5 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Chorion_2 PF03964.15 EGF78846.1 - 0.076 13.9 0.1 0.39 11.6 0.2 1.9 2 0 0 2 2 2 0 Chorion family 2 BTB_3 PF16017.5 EGF78847.1 - 0.047 13.8 0.1 0.099 12.8 0.1 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF78847.1 - 0.077 13.4 0.5 0.077 13.4 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3888) zf-RING_7 PF02591.15 EGF78847.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain AAA_16 PF13191.6 EGF78848.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Sigma70_r1_1 PF03979.14 EGF78848.1 - 0.015 15.4 0.1 0.05 13.7 0.1 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 XFP PF03894.15 EGF78849.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TAP_C PF03943.13 EGF78850.1 - 2.7e-13 49.3 0.1 5.4e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 EGF78850.1 - 8.7e-07 29.2 1.5 0.014 15.8 0.2 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF78850.1 - 7.6e-06 25.5 0.1 1.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 EGF78850.1 - 2.1e-05 24.2 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif NTF2 PF02136.20 EGF78850.1 - 7.9e-05 23.2 0.0 0.0074 16.9 0.0 2.6 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 EGF78850.1 - 0.072 12.9 2.7 0.33 10.7 2.8 2.0 1 1 0 1 1 1 0 Leucine rich repeat F-box-like PF12937.7 EGF78851.1 - 2.1e-07 30.7 0.9 1.1e-06 28.4 0.1 2.5 2 0 0 2 2 2 1 F-box-like Toxin_18 PF08087.11 EGF78851.1 - 0.011 15.7 3.1 0.087 12.8 0.4 3.1 2 0 0 2 2 2 0 Conotoxin O-superfamily F-box PF00646.33 EGF78851.1 - 0.043 13.7 1.7 0.69 9.9 0.0 3.2 2 0 0 2 2 2 0 F-box domain Zap1_zf2 PF18217.1 EGF78851.1 - 0.46 10.5 2.0 0.86 9.7 0.2 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 G6PD_C PF02781.16 EGF78852.1 - 9.3e-115 382.8 0.0 1.3e-114 382.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGF78852.1 - 1e-55 189.1 0.1 2.3e-55 188.0 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Pre-PUA PF17832.1 EGF78855.1 - 1.1e-25 90.2 0.2 1.7e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGF78855.1 - 4.1e-19 68.3 0.0 7e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 PUA domain Ndc80_HEC PF03801.13 EGF78856.1 - 1.9e-49 167.2 0.0 4e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 EGF78856.1 - 6.8e-14 51.7 0.2 6.8e-14 51.7 0.2 4.1 2 2 4 6 6 6 1 Domain of unknown function (DUF5595) HSBP1 PF06825.12 EGF78856.1 - 0.031 14.1 6.9 0.31 10.9 0.1 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 RNA_pol_L_2 PF13656.6 EGF78857.1 - 1.3e-32 111.3 0.0 1.6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGF78857.1 - 1.8e-16 59.3 0.0 2.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF5535 PF17687.1 EGF78858.1 - 0.028 14.6 0.2 0.073 13.2 0.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5535) EzrA PF06160.12 EGF78858.1 - 0.044 12.0 0.1 0.044 12.0 0.1 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF948 PF06103.11 EGF78858.1 - 0.094 13.0 0.5 0.46 10.8 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) EST1 PF10374.9 EGF78858.1 - 1.1 9.9 8.0 0.37 11.4 0.8 2.9 2 1 1 3 3 3 0 Telomerase activating protein Est1 APG12 PF04110.13 EGF78859.1 - 7.6e-34 116.0 0.1 1e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SMC_N PF02463.19 EGF78860.1 - 3.4e-08 33.2 0.0 4.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGF78860.1 - 7.7e-07 29.3 0.0 2.4e-06 27.7 0.0 1.7 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGF78860.1 - 8.3e-05 22.5 0.0 9.4e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGF78860.1 - 0.0049 16.6 0.0 0.0052 16.5 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGF78860.1 - 0.065 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FIBP PF05427.11 EGF78861.1 - 9.4e-80 268.6 0.4 1.1e-79 268.4 0.4 1.0 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Adap_comp_sub PF00928.21 EGF78862.1 - 5.8e-23 81.6 0.0 8.1e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGF78862.1 - 2e-06 27.8 0.2 3.2e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Nop PF01798.18 EGF78863.1 - 2.8e-76 256.0 0.0 3.8e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGF78863.1 - 1.1e-41 142.5 2.3 1.9e-41 141.7 2.3 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Adap_comp_sub PF00928.21 EGF78864.1 - 1.5e-92 309.7 0.2 6.6e-92 307.6 0.1 1.8 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGF78864.1 - 1.9e-10 40.9 1.4 3.5e-10 40.0 1.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGF78864.1 - 0.0079 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain RecU PF03838.14 EGF78864.1 - 0.069 13.2 0.4 35 4.4 0.0 3.3 3 1 0 3 3 3 0 Recombination protein U NSP2-B_epitope PF14757.6 EGF78865.1 - 0.062 13.0 2.2 0.11 12.2 2.2 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein BLYB PF05289.11 EGF78865.1 - 2 8.6 6.1 4.6 7.5 0.4 3.1 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein Velvet PF11754.8 EGF78866.1 - 1.1e-35 123.8 0.5 3.2e-33 115.7 0.1 5.1 3 2 1 4 4 4 2 Velvet factor Hydrolase_4 PF12146.8 EGF78867.1 - 2.8e-59 200.3 0.0 3.4e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGF78867.1 - 2.1e-18 66.9 0.1 3.1e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF78867.1 - 3.8e-12 47.3 0.0 4.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGF78867.1 - 1.2e-05 25.2 0.5 0.063 13.1 0.1 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGF78867.1 - 0.00012 21.6 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 EGF78867.1 - 0.003 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EGF78867.1 - 0.0041 16.1 0.0 0.0074 15.2 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 EGF78867.1 - 0.008 14.9 0.4 2.7 6.6 0.0 2.3 1 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EGF78867.1 - 0.052 13.4 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EGF78867.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EGF78867.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EGF78867.1 - 0.18 10.8 0.9 0.69 8.9 0.9 1.7 1 1 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.13 EGF78867.1 - 0.21 11.3 0.2 1.1 9.0 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein PAF-AH_p_II PF03403.13 EGF78867.1 - 0.23 9.9 0.0 11 4.4 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Sfi1 PF08457.10 EGF78869.1 - 5.7e-06 25.2 120.6 0.00058 18.5 53.0 6.8 3 2 1 4 4 4 4 Sfi1 spindle body protein MCM PF00493.23 EGF78870.1 - 7e-103 342.5 0.7 1.2e-102 341.7 0.7 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF78870.1 - 7.1e-38 129.3 0.1 1.3e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGF78870.1 - 7.1e-26 90.5 4.3 1.9e-25 89.1 2.9 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 EGF78870.1 - 5.4e-21 74.8 2.8 1.6e-20 73.4 2.8 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 EGF78870.1 - 1.9e-20 73.4 0.5 6.8e-20 71.6 0.5 2.0 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EGF78870.1 - 1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGF78870.1 - 0.00015 21.2 0.0 0.0016 17.9 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGF78870.1 - 0.0028 17.5 0.0 0.0086 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NUC130_3NT PF08158.12 EGF78870.1 - 0.042 14.2 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 NUC130/3NT domain RBFA PF02033.18 EGF78870.1 - 0.066 13.7 0.2 0.43 11.1 0.1 2.3 2 0 0 2 2 2 0 Ribosome-binding factor A Sigma54_activat PF00158.26 EGF78870.1 - 0.14 11.9 0.3 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Retrotrans_gag PF03732.17 EGF78870.1 - 1 9.7 2.8 56 4.1 0.1 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein TF_Zn_Ribbon PF08271.12 EGF78870.1 - 3.8 7.1 5.2 1.8 8.1 0.4 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding Acyltransferase PF01553.21 EGF78871.1 - 1.4e-13 50.6 0.1 2.5e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1752 PF08550.10 EGF78871.1 - 9.9e-05 22.1 2.7 9.9e-05 22.1 2.7 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) 4HB_MCP_1 PF12729.7 EGF78871.1 - 0.2 11.2 0.8 0.34 10.4 0.8 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AOX PF01786.17 EGF78872.1 - 9.8e-83 277.0 1.5 1.5e-82 276.4 1.5 1.2 1 0 0 1 1 1 1 Alternative oxidase SQHop_cyclase_C PF13243.6 EGF78873.1 - 7e-56 189.6 0.0 6e-51 173.4 0.0 2.4 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGF78873.1 - 2.6e-38 131.8 0.0 1.4e-32 113.0 0.0 4.2 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGF78873.1 - 4.1e-34 116.0 3.9 1.9e-09 37.1 0.2 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EGF78873.1 - 0.00061 18.9 0.3 0.074 12.1 0.0 3.4 2 1 2 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 EGF78873.1 - 0.065 12.5 0.2 45 3.2 0.0 4.0 4 2 2 6 6 6 0 Pectic acid lyase Mago-bind PF09282.10 EGF78873.1 - 0.065 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Mago binding Motile_Sperm PF00635.26 EGF78874.1 - 2e-19 69.4 0.0 4.6e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Cyclin PF08613.11 EGF78876.1 - 8.5e-12 45.7 0.2 1.3e-11 45.1 0.2 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGF78876.1 - 2.3e-06 27.3 0.1 4.2e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Histone PF00125.24 EGF78877.1 - 3.5e-52 176.2 1.9 3.9e-52 176.1 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGF78877.1 - 5.2e-05 23.3 0.3 9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGF78877.1 - 6.9e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGF78877.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGF78877.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGF78877.1 - 0.13 12.3 0.1 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Marek_A PF02124.15 EGF78878.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.4 1 1 0 1 1 1 0 Marek's disease glycoprotein A E1-E2_ATPase PF00122.20 EGF78879.1 - 1.7e-42 145.0 7.5 1.7e-42 145.0 7.5 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGF78879.1 - 5.4e-20 72.6 0.0 1.6e-19 71.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF78879.1 - 2.9e-15 55.7 0.4 1.7e-13 50.0 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF78879.1 - 0.0077 16.0 0.3 0.072 12.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGF78879.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) RNA_pol_I_A49 PF06870.12 EGF78880.1 - 6.3e-89 298.5 1.5 7.3e-89 298.3 1.5 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor MYCBPAP PF14646.6 EGF78880.1 - 0.056 12.4 0.4 0.092 11.7 0.4 1.3 1 0 0 1 1 1 0 MYCBP-associated protein family PHD20L1_u1 PF16660.5 EGF78880.1 - 0.07 13.9 0.2 0.16 12.7 0.2 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 SNF2_N PF00176.23 EGF78881.1 - 2.8e-55 187.4 0.0 5.3e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF78881.1 - 9.3e-16 58.2 0.0 6.2e-15 55.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Rad54_N PF08658.10 EGF78881.1 - 7.5e-09 36.0 0.0 1.3e-07 32.0 0.0 2.4 2 0 0 2 2 2 1 Rad54 N terminal ResIII PF04851.15 EGF78881.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGF78881.1 - 1.1e-05 24.7 0.0 3.3e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EGF78881.1 - 5.7e-05 22.4 0.1 0.00014 21.2 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EGF78881.1 - 0.046 14.0 0.2 10 6.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 EGF78881.1 - 0.095 12.3 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase DUF1864 PF08933.11 EGF78881.1 - 0.22 10.2 1.0 5.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) CH PF00307.31 EGF78882.1 - 3e-50 169.0 0.2 5.1e-25 87.8 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EGF78882.1 - 2.2e-11 43.7 0.7 1.1e-10 41.4 0.0 2.5 2 1 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EGF78882.1 - 1.9e-10 40.4 0.0 2.5e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_1 PF00036.32 EGF78882.1 - 3e-06 26.4 0.4 0.00014 21.2 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGF78882.1 - 9.4e-06 26.0 2.6 3.2e-05 24.3 2.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGF78882.1 - 1.6e-05 24.4 0.5 0.00023 20.8 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.21 EGF78882.1 - 0.00043 20.7 6.3 0.25 11.9 1.6 3.3 3 0 0 3 3 3 2 Spectrin repeat EF-hand_8 PF13833.6 EGF78882.1 - 0.0033 17.2 0.2 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 EGF78882.1 - 0.031 14.4 0.3 1.1 9.5 0.0 3.2 3 0 0 3 3 3 0 CH-like domain in sperm protein DUF4756 PF15948.5 EGF78882.1 - 0.052 13.4 0.4 5.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4756) Baculo_PEP_C PF04513.12 EGF78882.1 - 0.11 12.6 4.2 0.39 10.8 4.2 2.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Citrate_synt PF00285.21 EGF78883.1 - 4.2e-102 341.9 0.0 5.7e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Clat_adaptor_s PF01217.20 EGF78884.1 - 3.6e-42 143.6 1.3 4.3e-42 143.4 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GDI PF00996.18 EGF78885.1 - 8.8e-51 172.8 0.0 1e-34 119.8 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EGF78885.1 - 0.019 15.2 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3361 PF11841.8 EGF78885.1 - 0.048 13.6 0.5 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) HTH_micro PF17007.5 EGF78885.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 HTH-like Lycopene_cycl PF05834.12 EGF78885.1 - 0.076 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGF78885.1 - 0.16 11.0 0.1 0.29 10.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ATP-synt_C PF00137.21 EGF78886.1 - 2.3e-35 120.7 35.4 2.2e-22 79.2 12.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ATP1G1_PLM_MAT8 PF02038.16 EGF78886.1 - 6.2 6.3 5.9 29 4.2 0.3 2.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family U3snoRNP10 PF12397.8 EGF78887.1 - 8.7e-14 51.9 3.0 1.5e-13 51.1 0.7 2.3 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 FAM178 PF14816.6 EGF78887.1 - 0.038 13.0 0.1 0.061 12.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 HEAT PF02985.22 EGF78888.1 - 0.0024 18.0 0.3 10 6.7 0.0 4.9 3 0 0 3 3 3 1 HEAT repeat TFCD_C PF12612.8 EGF78888.1 - 0.012 15.4 3.2 4 7.2 0.1 4.3 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal TetR_C_34 PF17929.1 EGF78888.1 - 0.17 12.0 1.8 2.3 8.3 0.1 3.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain HEAT_2 PF13646.6 EGF78888.1 - 0.65 10.4 2.3 5.3 7.5 1.0 3.3 2 1 0 2 2 2 0 HEAT repeats BP28CT PF08146.12 EGF78889.1 - 1e-27 96.9 0.8 2.2e-26 92.6 0.5 2.2 2 0 0 2 2 2 1 BP28CT (NUC211) domain Vac14_Fab1_bd PF12755.7 EGF78889.1 - 0.00042 20.9 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGF78889.1 - 0.007 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats Pilin PF00114.19 EGF78889.1 - 0.034 15.1 0.0 0.051 14.5 0.0 1.2 1 0 0 1 1 1 0 Pilin (bacterial filament) Sigma54_DBD PF04552.13 EGF78889.1 - 0.066 12.9 0.1 0.33 10.7 0.1 1.9 1 1 0 1 1 1 0 Sigma-54, DNA binding domain HEAT_EZ PF13513.6 EGF78889.1 - 0.16 12.5 0.0 5.8 7.5 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Peptidase_S41 PF03572.18 EGF78890.1 - 1.6e-13 50.6 0.0 3.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EGF78890.1 - 0.041 13.7 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 PDZ domain DNA_pol3_beta_2 PF02767.16 EGF78890.1 - 0.045 14.0 0.1 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain FAT PF02259.23 EGF78892.1 - 3e-72 243.7 3.7 6e-72 242.7 3.7 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGF78892.1 - 6.7e-31 108.0 0.3 1.4e-30 106.9 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGF78892.1 - 0.012 15.4 0.0 0.046 13.6 0.0 2.1 1 0 0 1 1 1 0 FATC domain FAS_N PF17828.1 EGF78892.1 - 0.22 11.5 1.3 2.3 8.2 0.5 3.0 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta RasGEF_N_2 PF14663.6 EGF78892.1 - 0.55 10.7 3.0 4.1 7.9 0.0 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FAT PF02259.23 EGF78893.1 - 2.6e-116 388.6 1.4 2.6e-116 388.6 1.4 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGF78893.1 - 9.9e-76 254.8 0.1 1.8e-75 254.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGF78893.1 - 2.3e-58 196.7 11.3 3.1e-54 183.2 0.1 5.6 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGF78893.1 - 1.9e-41 140.5 1.4 4.6e-41 139.2 0.2 2.5 2 0 0 2 2 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 EGF78893.1 - 4.8e-11 42.3 2.5 1.4e-10 40.8 1.0 2.7 3 0 0 3 3 2 1 FATC domain HEAT_2 PF13646.6 EGF78893.1 - 1.1e-10 41.8 9.5 0.0012 19.2 0.0 9.3 7 5 2 10 10 10 2 HEAT repeats HEAT PF02985.22 EGF78893.1 - 5.9e-10 38.5 23.8 0.14 12.5 0.2 12.7 15 0 0 15 15 12 3 HEAT repeat HEAT_EZ PF13513.6 EGF78893.1 - 1.5e-07 31.7 18.9 0.1 13.1 0.1 10.4 11 1 1 12 12 10 2 HEAT-like repeat TPR_16 PF13432.6 EGF78893.1 - 1.1e-05 25.9 1.0 0.11 13.1 0.5 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat RIX1 PF08167.12 EGF78893.1 - 1.4e-05 24.9 5.4 0.71 9.6 0.0 6.2 6 0 0 6 6 6 2 rRNA processing/ribosome biogenesis TPR_19 PF14559.6 EGF78893.1 - 5.2e-05 23.7 0.2 0.87 10.1 0.1 3.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 EGF78893.1 - 0.00021 21.8 3.8 60 4.3 0.1 6.6 4 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region DNA_alkylation PF08713.11 EGF78893.1 - 0.0069 16.1 1.4 1.5 8.5 0.0 4.0 4 0 0 4 4 4 1 DNA alkylation repair enzyme Dopey_N PF04118.14 EGF78893.1 - 0.012 14.7 2.0 0.074 12.2 0.6 2.9 2 0 0 2 2 2 0 Dopey, N-terminal Cohesin_HEAT PF12765.7 EGF78893.1 - 0.044 14.1 0.7 15 6.0 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EGF78893.1 - 0.067 13.2 13.1 0.14 12.2 0.4 5.7 5 3 1 7 7 6 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGF78893.1 - 0.13 11.8 0.0 0.13 11.8 0.0 4.9 5 1 0 5 5 5 0 CLASP N terminal Tti2 PF10521.9 EGF78893.1 - 7.6 6.0 7.8 19 4.7 0.1 4.6 4 1 2 6 6 6 0 Tti2 family Lactamase_B_6 PF16661.5 EGF78894.1 - 8.2e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGF78894.1 - 0.06 12.6 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative beta-lactamase-like family Mito_carr PF00153.27 EGF78895.1 - 2.1e-67 223.1 2.2 1.4e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 EGF78896.1 - 2.9e-10 40.1 0.7 4.8e-10 39.4 0.1 1.7 2 0 0 2 2 2 1 DnaJ domain Vac_Fusion PF02346.16 EGF78896.1 - 0.21 11.3 0.2 0.4 10.3 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Cyt_bd_oxida_I PF01654.17 EGF78896.1 - 0.65 8.5 5.4 0.22 10.1 2.5 1.5 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit I Ax_dynein_light PF10211.9 EGF78898.1 - 6.3e-06 26.3 10.1 6.3e-06 26.3 10.1 3.3 3 1 1 4 4 4 1 Axonemal dynein light chain Nbl1_Borealin_N PF10444.9 EGF78898.1 - 0.04 13.6 2.2 0.32 10.7 0.0 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Aida_N PF08910.10 EGF78898.1 - 0.85 10.0 5.3 1.1 9.7 0.2 3.6 2 1 1 3 3 3 0 Aida N-terminus PMC2NT PF08066.12 EGF78898.1 - 1.3 9.8 6.7 3.3 8.5 0.1 3.9 3 2 0 3 3 3 0 PMC2NT (NUC016) domain DUF3492 PF11997.8 EGF78898.1 - 2.8 7.6 6.1 15 5.2 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Transglut_core PF01841.19 EGF78899.1 - 0.0002 21.8 0.0 0.00069 20.0 0.0 2.0 1 1 0 1 1 1 1 Transglutaminase-like superfamily KIP1 PF07765.12 EGF78899.1 - 0.23 11.6 4.2 1.1 9.4 0.8 3.1 2 0 0 2 2 2 0 KIP1-like protein Sec8_exocyst PF04048.14 EGF78900.1 - 2.7e-27 95.4 0.3 1.1e-26 93.5 0.3 2.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EGF78900.1 - 0.0008 18.8 1.3 0.0033 16.8 1.3 2.1 1 1 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF5344 PF17279.2 EGF78900.1 - 0.077 13.6 0.0 0.077 13.6 0.0 4.0 5 0 0 5 5 5 0 Family of unknown function (DUF5344) RhoGEF PF00621.20 EGF78900.1 - 0.14 12.4 2.7 0.33 11.2 0.0 2.8 3 0 0 3 3 3 0 RhoGEF domain COG2 PF06148.11 EGF78900.1 - 1.1 9.4 4.4 1.9 8.6 0.2 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Dala_Dala_lig_C PF07478.13 EGF78901.1 - 2.7e-10 40.1 0.0 4.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 EGF78901.1 - 0.00096 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 EGF78901.1 - 0.0017 18.0 0.0 0.0061 16.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain IF-2B PF01008.17 EGF78902.1 - 2e-66 224.1 0.1 2.4e-66 223.9 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DHFR_1 PF00186.19 EGF78902.1 - 0.03 14.0 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Dihydrofolate reductase Rbsn PF11464.8 EGF78902.1 - 0.21 11.4 0.9 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Rabenosyn Rab binding domain PWI PF01480.17 EGF78903.1 - 3.3e-07 30.5 0.1 7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 PWI domain zf_CCCH_4 PF18345.1 EGF78903.1 - 0.00093 19.2 3.3 0.0017 18.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EGF78903.1 - 0.0042 17.1 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 EGF78903.1 - 0.0059 17.3 0.5 0.016 15.9 0.5 1.8 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 EGF78903.1 - 0.13 12.2 5.3 0.24 11.4 5.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EGF78903.1 - 0.18 11.6 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6_N PF17675.1 EGF78903.1 - 8 7.0 12.0 3.6 8.1 8.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Frataxin_Cyay PF01491.16 EGF78905.1 - 4.2e-38 129.7 0.1 4.7e-38 129.6 0.1 1.0 1 0 0 1 1 1 1 Frataxin-like domain EF-hand_6 PF13405.6 EGF78906.1 - 3.4e-09 35.9 1.5 0.023 14.6 0.0 5.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EGF78906.1 - 2.1e-07 30.0 0.0 0.041 13.4 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGF78906.1 - 2.5e-07 31.0 2.9 0.0057 17.1 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGF78906.1 - 0.00028 20.3 0.0 0.092 12.3 0.0 2.9 2 0 0 2 2 2 2 EF hand Methyltransf_FA PF12248.8 EGF78906.1 - 0.0012 19.1 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase EF-hand_13 PF17958.1 EGF78906.1 - 0.0031 17.3 0.1 0.11 12.3 0.0 2.6 1 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGF78906.1 - 0.044 13.6 0.0 2.6 8.0 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair PDEase_I PF00233.19 EGF78907.1 - 3.5e-69 233.2 3.8 7.8e-69 232.0 3.8 1.6 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ubiquitin PF00240.23 EGF78908.1 - 3.2e-35 119.7 0.5 3.5e-35 119.6 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGF78908.1 - 7.7e-17 60.9 0.6 8.5e-17 60.8 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGF78908.1 - 4.1e-06 27.2 0.1 1.7e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGF78908.1 - 0.0012 18.8 0.3 1.2 9.2 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EGF78908.1 - 0.0015 18.4 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGF78908.1 - 0.0016 18.7 0.1 0.002 18.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGF78908.1 - 0.0021 18.2 0.1 0.0045 17.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGF78908.1 - 0.017 15.7 0.1 0.019 15.5 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGF78908.1 - 0.039 13.8 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HATPase_c PF02518.26 EGF78908.1 - 0.098 13.2 0.1 0.11 13.0 0.1 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UBA PF00627.31 EGF78910.1 - 0.15 12.0 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 UBA/TS-N domain YHS PF04945.13 EGF78910.1 - 0.19 11.8 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 YHS domain Spo12 PF05032.12 EGF78912.1 - 8.5e-09 35.2 1.4 1.8e-08 34.1 1.4 1.5 1 0 0 1 1 1 1 Spo12 family RA PF00788.23 EGF78913.1 - 0.00038 21.0 0.0 0.00073 20.1 0.0 1.5 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Dymeclin PF09742.9 EGF78915.1 - 8.7e-78 262.3 12.3 4.9e-74 249.9 9.4 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 EGF78915.1 - 2.3e-05 22.8 0.6 2.3e-05 22.8 0.6 2.6 3 0 0 3 3 3 2 High-temperature-induced dauer-formation protein End3 PF12761.7 EGF78916.1 - 2e-06 28.1 5.4 0.00021 21.5 0.1 2.3 1 1 1 2 2 2 2 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EGF78916.1 - 0.00013 21.9 0.0 0.00037 20.4 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Nup54 PF13874.6 EGF78916.1 - 0.052 13.7 2.0 0.098 12.8 2.0 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4586 PF15239.6 EGF78917.1 - 1.6e-89 301.1 8.6 1.8e-89 300.9 8.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.25 EGF78919.1 - 7e-62 209.2 0.0 8.3e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78919.1 - 8.7e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF78919.1 - 6.2e-05 21.9 0.0 9.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF78919.1 - 0.00012 21.5 0.0 0.00042 19.7 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EGF78919.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGF78919.1 - 0.017 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGF78919.1 - 0.031 13.3 0.0 0.092 11.8 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 EGF78919.1 - 0.058 12.4 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EGF78919.1 - 0.15 12.0 0.1 0.56 10.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family GATA PF00320.27 EGF78920.1 - 4.8e-10 38.9 5.5 1.4e-09 37.4 5.5 1.8 1 0 0 1 1 1 1 GATA zinc finger Pyr_redox_2 PF07992.14 EGF78921.1 - 9.1e-46 156.4 0.0 1.3e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 EGF78921.1 - 2.3e-38 131.5 1.7 8.2e-24 84.4 0.0 2.8 2 1 1 3 3 3 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 EGF78921.1 - 1.9e-09 37.9 0.3 1.8e-08 34.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGF78921.1 - 2.6e-07 30.1 0.0 0.009 15.2 0.0 3.9 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGF78921.1 - 8e-06 25.9 4.8 0.069 13.1 0.0 4.1 2 2 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EGF78921.1 - 0.00017 21.3 3.6 0.04 13.5 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGF78921.1 - 0.0012 17.7 0.1 0.42 9.3 0.1 2.9 3 1 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 EGF78921.1 - 0.013 14.8 0.3 0.083 12.2 0.0 2.0 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EGF78921.1 - 0.024 13.5 1.3 3.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase ECR1_N PF14382.6 EGF78922.1 - 6.1e-16 57.9 0.1 1.2e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EGF78922.1 - 1.4e-10 41.4 0.2 3.1e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 KH domain DUF3524 PF12038.8 EGF78922.1 - 0.19 11.5 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) LRR_9 PF14580.6 EGF78923.1 - 4.8e-12 45.7 2.3 7.6e-12 45.1 2.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGF78923.1 - 2.1e-08 34.3 20.8 1.6e-05 25.2 3.4 4.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF78923.1 - 4.3e-08 32.8 25.9 1.4e-05 24.8 9.6 2.9 2 1 2 4 4 4 3 Leucine rich repeat SAICAR_synt PF01259.18 EGF78924.1 - 2.5e-101 338.5 0.0 3.1e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Ribosomal_L18A PF01775.17 EGF78925.1 - 1.2e-55 186.7 2.1 1.6e-55 186.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Acetyltransf_1 PF00583.25 EGF78926.1 - 2.7e-07 30.8 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF78926.1 - 1.6e-05 24.8 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF78926.1 - 0.00021 21.2 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGF78926.1 - 0.0013 19.2 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGF78926.1 - 0.0046 17.1 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EGF78926.1 - 0.019 15.7 0.0 0.026 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGF78926.1 - 0.075 12.5 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase GTP_EFTU PF00009.27 EGF78927.1 - 2.2e-59 200.2 0.0 3.4e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EGF78927.1 - 3e-24 84.9 0.0 5.7e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGF78927.1 - 4e-20 71.7 0.0 1e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGF78927.1 - 5.5e-08 33.1 0.1 2e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EGF78927.1 - 1.3e-06 28.2 0.1 2.8e-05 23.9 0.0 3.0 4 0 0 4 4 4 1 Elongation factor G, domain IV RF3_C PF16658.5 EGF78927.1 - 4.1e-06 26.6 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGF78927.1 - 0.00033 20.7 0.0 0.0007 19.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mg_trans_NIPA PF05653.14 EGF78928.1 - 1.9e-105 352.2 15.5 2.2e-105 352.0 15.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGF78928.1 - 0.0002 21.5 5.6 0.0002 21.5 5.6 3.6 3 1 0 3 3 3 2 EamA-like transporter family Wzy_C_2 PF11846.8 EGF78928.1 - 0.19 11.6 0.4 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Pan3_PK PF18101.1 EGF78929.1 - 5.8e-62 207.7 0.2 1.2e-61 206.7 0.2 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGF78929.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF386 PF04074.12 EGF78929.1 - 0.03 14.2 3.7 0.077 12.9 3.7 1.7 1 0 0 1 1 1 0 YhcH/YjgK/YiaL L31 PF09784.9 EGF78931.1 - 2.6e-17 63.1 0.2 2.6e-17 63.1 0.2 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L31 Ribosomal_L41 PF05162.13 EGF78931.1 - 1.7e-08 34.3 29.3 1.7e-08 34.3 29.3 2.5 3 0 0 3 3 3 1 Ribosomal protein L41 cwf18 PF08315.12 EGF78932.1 - 6.1e-38 130.5 12.3 7.7e-38 130.2 12.3 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF948 PF06103.11 EGF78932.1 - 0.57 10.5 3.1 2.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ArAE_2_N PF10337.9 EGF78932.1 - 1.6 7.7 4.0 1.9 7.4 4.0 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Muted PF14942.6 EGF78932.1 - 4.4 7.6 8.6 1.5 9.1 4.9 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Glucosamine_iso PF01182.20 EGF78933.1 - 2e-70 237.2 0.0 2.3e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SWI-SNF_Ssr4 PF08549.10 EGF78934.1 - 7.1e-20 71.2 0.9 9e-12 44.5 0.0 2.2 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) CG-1 PF03859.16 EGF78934.1 - 0.011 15.5 0.0 0.048 13.4 0.0 2.0 1 1 0 1 1 1 0 CG-1 domain SET PF00856.28 EGF78935.1 - 1.2e-17 64.8 0.1 1.2e-17 64.8 0.1 4.6 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EGF78935.1 - 1.2e-12 47.6 6.7 3.7e-12 46.1 6.7 1.9 1 0 0 1 1 1 1 AWS domain SRI PF08236.11 EGF78935.1 - 3.9e-05 23.7 1.3 3.9e-05 23.7 1.3 3.1 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain MFS_1 PF07690.16 EGF78936.1 - 2.3e-28 99.1 34.0 4.6e-20 71.8 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF78936.1 - 1e-22 80.7 18.1 1.4e-22 80.2 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGF78936.1 - 0.056 12.7 19.8 0.059 12.7 6.0 2.4 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB DctQ PF04290.12 EGF78936.1 - 0.64 9.9 11.0 4.8 7.1 0.0 4.5 4 1 0 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component MotA_ExbB PF01618.16 EGF78936.1 - 7.5 6.3 6.6 0.61 9.9 1.0 2.1 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family PPR_2 PF13041.6 EGF78937.1 - 1.1e-47 160.0 4.7 5.5e-11 42.5 0.1 9.3 6 3 2 9 9 9 6 PPR repeat family PPR PF01535.20 EGF78937.1 - 5.1e-31 104.7 11.7 0.0064 16.7 0.0 10.5 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 EGF78937.1 - 8.1e-31 105.9 4.0 3e-08 33.6 0.0 8.4 3 2 7 10 10 10 9 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF78937.1 - 6.9e-27 92.8 0.0 0.0048 16.6 0.0 10.2 10 0 0 10 10 10 7 PPR repeat PPR_long PF17177.4 EGF78937.1 - 2e-26 92.7 0.0 5.7e-09 35.7 0.0 5.9 4 3 2 6 6 6 5 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 EGF78937.1 - 8e-06 25.0 0.1 0.036 12.9 0.0 3.2 3 1 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 EGF78937.1 - 0.00063 20.4 0.0 16 6.6 0.0 5.4 6 1 1 7 7 7 1 Tetratricopeptide repeat RPM2 PF08579.11 EGF78937.1 - 0.0039 17.6 4.9 33 4.9 0.2 6.5 4 2 2 6 6 6 0 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EGF78937.1 - 0.0061 16.4 3.6 20 5.1 0.0 5.0 4 1 2 6 6 6 0 Mitochondrial ATPase expression UvsW PF11637.8 EGF78938.1 - 0.13 12.3 0.0 0.72 10.0 0.1 2.0 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Gcn1_N PF12074.8 EGF78939.1 - 8.6e-34 117.4 4.8 8.6e-34 117.4 4.8 3.7 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EGF78939.1 - 2.7e-26 89.4 29.4 0.014 15.6 0.0 20.6 24 0 0 24 24 21 5 HEAT repeat CLASP_N PF12348.8 EGF78939.1 - 1.7e-23 83.4 0.7 8.3e-07 28.8 0.0 8.2 7 1 1 8 8 8 4 CLASP N terminal HEAT_EZ PF13513.6 EGF78939.1 - 1.3e-21 76.6 22.8 0.01 16.3 0.0 16.5 16 3 3 19 19 18 6 HEAT-like repeat HEAT_2 PF13646.6 EGF78939.1 - 1.3e-19 70.4 18.6 0.0013 19.1 0.0 12.2 11 3 1 12 12 11 5 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF78939.1 - 1.5e-11 44.7 0.0 0.2 12.3 0.0 8.5 9 2 2 11 11 10 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGF78939.1 - 7.3e-11 42.4 15.7 0.85 9.6 0.0 11.0 11 2 1 13 13 13 4 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 EGF78939.1 - 6.8e-08 32.3 10.2 0.26 11.2 0.0 9.0 9 1 0 9 9 9 1 UME (NUC010) domain tRNA_int_endo PF01974.17 EGF78939.1 - 1.1e-05 25.4 0.2 0.00045 20.2 0.3 3.2 3 0 0 3 3 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF3385 PF11865.8 EGF78939.1 - 3.1e-05 23.9 0.2 12 5.8 0.0 6.8 6 1 0 6 6 6 0 Domain of unknown function (DUF3385) ParcG PF10274.9 EGF78939.1 - 0.00064 19.9 2.0 3.3 7.8 0.0 5.6 4 1 1 5 5 5 1 Parkin co-regulated protein Condensin2nSMC PF12422.8 EGF78939.1 - 0.022 14.9 0.1 22 5.2 0.0 4.5 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DUF937 PF06078.11 EGF78939.1 - 0.082 13.5 6.4 1.2 9.8 0.1 4.7 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF937) DUF3361 PF11841.8 EGF78939.1 - 0.54 10.2 3.8 1.1 9.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) Cohesin_HEAT PF12765.7 EGF78939.1 - 5.1 7.5 9.1 21 5.6 0.1 5.9 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_L6e PF01159.19 EGF78940.1 - 8.5e-41 139.0 1.2 1.1e-40 138.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e DUF3586 PF12131.8 EGF78941.1 - 0.18 12.0 3.7 6.1 7.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) PI3K_1B_p101 PF10486.9 EGF78942.1 - 0.1 10.4 6.5 0.15 9.8 6.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 EGF78943.1 - 2.2e-23 83.0 0.0 2.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78943.1 - 5.4e-09 35.7 0.0 1.1e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF78943.1 - 3.2e-07 30.0 0.0 3.6e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF78943.1 - 0.0033 16.2 0.0 0.004 16.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGF78943.1 - 0.11 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Septin PF00735.18 EGF78944.1 - 7.1e-109 363.4 0.1 1e-108 362.9 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGF78944.1 - 4.1e-07 30.1 0.0 8.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF78944.1 - 2.7e-06 27.1 0.4 0.00015 21.4 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF78944.1 - 6.2e-05 23.0 0.4 0.00031 20.7 0.2 2.2 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 EGF78944.1 - 0.00055 19.6 0.1 0.0016 18.1 0.1 1.8 1 1 0 1 1 1 1 Ras family Pox_A32 PF04665.12 EGF78944.1 - 0.00094 18.7 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_16 PF13191.6 EGF78944.1 - 0.0021 18.5 0.1 0.0068 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGF78944.1 - 0.0029 17.9 0.1 0.0085 16.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EGF78944.1 - 0.0041 16.4 0.0 0.0072 15.6 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain AIG1 PF04548.16 EGF78944.1 - 0.007 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EGF78944.1 - 0.0085 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EGF78944.1 - 0.0089 15.8 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 EGF78944.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EGF78944.1 - 0.018 14.7 1.3 0.02 14.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF78944.1 - 0.021 15.2 0.0 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EGF78944.1 - 0.033 14.7 0.1 0.091 13.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter FOXP-CC PF16159.5 EGF78944.1 - 0.038 14.6 1.4 0.038 14.6 1.4 2.2 2 0 0 2 2 1 0 FOXP coiled-coil domain FtsK_SpoIIIE PF01580.18 EGF78944.1 - 0.04 13.3 1.1 0.063 12.6 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 EGF78944.1 - 0.063 12.6 0.2 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EGF78944.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EGF78944.1 - 0.14 11.9 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.6 EGF78944.1 - 0.25 10.3 0.0 0.25 10.3 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3987) DUF29 PF01724.16 EGF78944.1 - 0.61 10.3 7.5 0.37 11.0 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF29 Dynamin_N PF00350.23 EGF78944.1 - 1.8 8.6 7.3 17 5.4 0.2 3.2 2 1 1 3 3 3 0 Dynamin family Tubulin PF00091.25 EGF78946.1 - 1.4e-69 234.2 0.0 2.8e-69 233.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF78946.1 - 1.8e-43 147.7 0.1 2.8e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGF78946.1 - 2.1e-05 24.8 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGF78946.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGF78946.1 - 0.018 14.3 0.0 0.055 12.6 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Pkinase PF00069.25 EGF78947.1 - 3e-56 190.7 0.0 3.5e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF78947.1 - 1.9e-43 148.6 0.0 2.3e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF78947.1 - 1.3e-06 27.5 0.0 1.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGF78947.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF78947.1 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CNH PF00780.22 EGF78948.1 - 9.8e-14 51.6 0.1 1.2e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 CNH domain ANAPC4_WD40 PF12894.7 EGF78948.1 - 0.17 12.2 0.4 0.84 10.0 0.0 2.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Med4 PF10018.9 EGF78949.1 - 9.1e-15 54.8 4.5 1.1e-14 54.6 4.5 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HBM PF16591.5 EGF78949.1 - 0.0024 17.3 2.4 0.0038 16.7 2.4 1.3 1 0 0 1 1 1 1 Helical bimodular sensor domain DUF3323 PF11796.8 EGF78949.1 - 0.044 13.7 0.0 0.055 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ATP-synt_ab PF00006.25 EGF78950.1 - 4.7e-63 212.7 0.1 1.5e-62 211.1 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGF78950.1 - 1.5e-23 83.1 1.2 3.2e-23 82.0 1.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EGF78950.1 - 0.02 14.1 1.2 0.028 13.6 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 EGF78950.1 - 0.031 14.2 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EGF78950.1 - 0.047 14.1 0.0 0.76 10.2 0.0 2.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGF78950.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGF78950.1 - 0.067 13.6 0.1 0.19 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EGF78950.1 - 0.081 13.3 1.5 0.28 11.5 0.4 2.2 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EGF78950.1 - 0.4 10.0 2.2 0.34 10.2 0.6 1.7 2 0 0 2 2 2 0 KaiC DUF3524 PF12038.8 EGF78951.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) Rad10 PF03834.14 EGF78952.1 - 6.9e-47 158.2 0.0 1.3e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGF78952.1 - 8e-09 36.0 0.0 1.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EGF78952.1 - 1.6e-05 24.9 0.1 3.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 EGF78952.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNA12 PF10443.9 EGF78953.1 - 6e-99 331.8 0.0 5.8e-53 180.2 0.0 2.1 1 1 1 2 2 2 2 RNA12 protein RRM_1 PF00076.22 EGF78953.1 - 7e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 EGF78953.1 - 2.2e-07 31.4 0.0 3.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGF78953.1 - 4.3e-06 26.8 0.1 1.5e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGF78953.1 - 0.0075 16.6 0.0 0.018 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGF78953.1 - 0.013 15.6 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGF78953.1 - 0.14 12.6 0.0 19 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MCD PF05292.11 EGF78954.1 - 1.9e-56 191.5 0.0 3.9e-40 138.0 0.0 2.1 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain DUF4246 PF14033.6 EGF78956.1 - 1.2e-28 100.4 0.0 1.5e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) MeaB PF03308.16 EGF78958.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGF78958.1 - 0.041 13.9 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 EGF78958.1 - 0.051 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EGF78958.1 - 0.053 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RHSP PF07999.11 EGF78958.1 - 0.17 10.6 0.1 0.68 8.7 0.0 1.9 2 1 1 3 3 3 0 Retrotransposon hot spot protein Pkinase PF00069.25 EGF78959.1 - 5.6e-12 45.6 0.0 2e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF78959.1 - 7.1e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF78959.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF78959.1 - 0.0082 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF78959.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF78959.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF78959.1 - 0.021 13.6 0.6 0.032 13.0 0.6 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF78959.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF78959.1 - 0.075 12.5 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DnaJ-X PF14308.6 EGF78960.1 - 1.7e-41 142.0 0.5 2.8e-41 141.3 0.5 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF78960.1 - 3e-23 81.7 1.0 7.5e-23 80.4 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain PMG PF05287.12 EGF78961.1 - 0.018 15.1 2.9 0.034 14.2 2.9 1.5 1 0 0 1 1 1 0 PMG protein YqgF PF14639.6 EGF78961.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Mod_r PF07200.13 EGF78961.1 - 0.064 13.4 4.6 0.23 11.6 4.0 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Erp_C PF06780.11 EGF78961.1 - 0.077 13.0 4.9 0.12 12.4 4.9 1.2 1 0 0 1 1 1 0 Erp protein C-terminus M PF02370.16 EGF78961.1 - 1 10.2 5.8 11 6.9 0.7 2.8 2 0 0 2 2 2 0 M protein repeat Asp PF00026.23 EGF78963.1 - 2.7e-12 46.7 0.4 4.7e-12 46.0 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78963.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Sec2p PF06428.11 EGF78965.1 - 0.14 12.1 3.3 6.1 6.9 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF78965.1 - 0.93 9.7 4.7 16 5.7 4.6 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IstB_IS21 PF01695.17 EGF78966.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Imm74 PF15603.6 EGF78968.1 - 0.064 13.5 0.9 17 5.6 0.1 3.3 2 1 1 3 3 3 0 Immunity protein 74 DUF1539 PF07560.11 EGF78968.1 - 0.071 13.2 6.4 4.2 7.5 0.7 3.9 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1539) DUF4476 PF14771.6 EGF78968.1 - 0.93 9.8 4.8 2.8 8.3 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4476) Asp PF00026.23 EGF78969.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 Eukaryotic aspartyl protease Asp PF00026.23 EGF78970.1 - 9.8e-07 28.5 0.1 1.2e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Diacid_rec PF05651.13 EGF78970.1 - 0.0033 17.1 0.1 0.0052 16.5 0.1 1.4 1 0 0 1 1 1 1 Putative sugar diacid recognition GLE1 PF07817.13 EGF78971.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein YpjP PF14005.6 EGF78972.1 - 0.019 15.0 3.0 6.6 6.8 0.2 3.2 1 1 2 3 3 3 0 YpjP-like protein TolA_bind_tri PF16331.5 EGF78972.1 - 0.026 14.6 5.9 26 5.0 0.1 4.2 4 0 0 4 4 4 0 TolA binding protein trimerisation Pox_A_type_inc PF04508.12 EGF78972.1 - 0.034 14.0 4.6 34 4.5 0.1 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1098 PF06497.11 EGF78972.1 - 0.071 13.6 3.3 54 4.3 0.1 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF1098) DUF4504 PF14953.6 EGF78972.1 - 0.11 11.9 0.8 1.7 8.0 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4504) Rootletin PF15035.6 EGF78972.1 - 0.3 11.1 12.6 3.6 7.6 2.2 3.5 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion ARGLU PF15346.6 EGF78972.1 - 0.34 10.8 8.3 0.16 11.9 5.1 2.1 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 PspB PF06667.12 EGF78972.1 - 0.43 10.7 2.0 87 3.3 0.0 3.9 4 0 0 4 4 4 0 Phage shock protein B Tropomyosin PF00261.20 EGF78972.1 - 0.99 8.7 5.8 5 6.4 0.3 2.5 1 1 0 2 2 2 0 Tropomyosin CLZ PF16526.5 EGF78972.1 - 8 6.9 8.4 1.1e+02 3.3 0.2 4.5 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran PF00005.27 EGF78973.1 - 1.9e-26 93.2 0.0 3.9e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGF78973.1 - 6e-18 65.1 27.3 9e-18 64.5 27.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGF78973.1 - 3.7e-11 43.4 0.0 2.5e-07 30.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF78973.1 - 0.005 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGF78973.1 - 0.038 14.5 0.1 0.066 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGF78973.1 - 0.039 13.9 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EGF78973.1 - 0.15 11.7 0.0 0.86 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EGF78975.1 - 9.2e-07 29.5 5.5 3.9 8.5 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EGF78975.1 - 0.033 13.5 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DX PF01666.17 EGF78976.1 - 0.34 11.4 6.3 1 9.8 0.3 2.1 1 1 1 2 2 2 0 DX module Neurokinin_B PF03823.14 EGF78976.1 - 0.76 9.9 3.0 6.3 6.9 0.5 2.3 2 0 0 2 2 2 0 Neurokinin B Opy2 PF09463.10 EGF78976.1 - 1.7 9.0 7.4 8.4 6.8 1.2 2.7 1 1 1 2 2 2 0 Opy2 protein Dickkopf_N PF04706.12 EGF78976.1 - 1.7 9.2 10.4 2.8 8.5 0.5 2.4 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region Lustrin_cystein PF14625.6 EGF78976.1 - 2 8.9 12.7 0.13 12.7 2.8 2.4 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain EF-hand_4 PF12763.7 EGF78977.1 - 5.1e-22 77.8 0.0 5.2e-14 52.1 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand RhoGEF PF00621.20 EGF78977.1 - 1.5e-20 74.2 0.2 3.4e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 EGF78977.1 - 6.8e-15 54.4 0.1 2.5e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGF78977.1 - 7e-13 48.0 0.0 2.6e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 EGF78977.1 - 2.1e-11 43.5 0.3 0.00013 21.7 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain DUF3499 PF12005.8 EGF78977.1 - 0.003 18.2 0.2 0.021 15.4 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3499) SH3_3 PF08239.11 EGF78977.1 - 0.042 14.1 1.4 0.87 9.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain DUF4111 PF13427.6 EGF78978.1 - 0.011 15.9 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) MRP-L27 PF09809.9 EGF78979.1 - 9.8e-20 70.5 0.0 1.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Phosphoesterase PF04185.14 EGF78980.1 - 5.5e-74 249.5 0.3 7.9e-74 249.0 0.3 1.2 1 0 0 1 1 1 1 Phosphoesterase family MgtE PF01769.16 EGF78981.1 - 3.6e-16 59.7 6.6 3.6e-16 59.7 6.6 1.7 2 0 0 2 2 2 1 Divalent cation transporter Phage_holin_3_3 PF16083.5 EGF78981.1 - 0.042 14.0 4.9 0.12 12.5 4.9 1.7 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Mito_carr PF00153.27 EGF78982.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein Transket_pyr PF02779.24 EGF78984.1 - 4.2e-46 156.9 0.0 6.7e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGF78984.1 - 1.3e-39 134.9 0.1 2.4e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGF78984.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II TPR_19 PF14559.6 EGF78985.1 - 2.7e-11 43.8 1.5 0.1 13.1 0.0 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF78985.1 - 1e-08 35.3 0.5 0.74 10.2 0.1 5.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF78985.1 - 2.6e-07 30.2 16.9 0.059 13.5 0.3 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF78985.1 - 8e-07 29.6 0.1 0.055 14.1 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF78985.1 - 1.6e-06 28.3 22.2 0.016 15.4 1.4 5.2 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGF78985.1 - 9.3e-05 22.1 14.9 0.05 13.4 0.4 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF78985.1 - 0.0073 17.0 0.2 1.1e+02 4.1 0.0 5.5 6 2 2 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 EGF78985.1 - 0.24 11.5 1.8 5.9 7.0 0.1 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EGF78985.1 - 0.35 11.2 7.9 16 6.0 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF78985.1 - 0.85 9.8 8.5 9.5 6.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF78985.1 - 1.3 9.1 6.0 0.47 10.6 0.2 3.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Pam17 PF08566.10 EGF78986.1 - 1.9e-32 112.4 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2062 PF09835.9 EGF78986.1 - 0.06 13.2 0.2 0.083 12.7 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Cad PF03596.13 EGF78986.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Cadmium resistance transporter Arrestin_N PF00339.29 EGF78987.1 - 6.2e-09 36.1 0.0 2.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SH3_9 PF14604.6 EGF78987.1 - 3.6e-05 23.6 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF78987.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arrestin_C PF02752.22 EGF78987.1 - 0.0047 17.4 0.8 0.066 13.7 0.0 3.1 4 0 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain SH3_1 PF00018.28 EGF78987.1 - 0.01 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Asp PF00026.23 EGF78990.1 - 3e-14 53.2 0.1 4.7e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF78990.1 - 1.2e-05 25.1 0.0 4.8e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DivIC PF04977.15 EGF78991.1 - 0.0046 16.7 2.1 0.39 10.5 0.4 2.2 2 0 0 2 2 2 1 Septum formation initiator GidB PF02527.15 EGF78991.1 - 0.0088 15.4 0.4 0.011 15.1 0.4 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Arfaptin PF06456.13 EGF78991.1 - 0.019 14.5 3.3 0.1 12.2 0.1 2.1 1 1 1 2 2 2 0 Arfaptin-like domain FapA PF03961.13 EGF78991.1 - 0.026 13.2 0.5 0.029 13.0 0.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TSC22 PF01166.18 EGF78991.1 - 0.029 14.7 1.4 2.7 8.4 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family UPF0242 PF06785.11 EGF78991.1 - 0.034 14.2 3.1 0.043 13.9 3.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YkyA PF10368.9 EGF78991.1 - 0.035 13.8 3.1 0.045 13.4 3.1 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein YabA PF06156.13 EGF78991.1 - 0.043 14.4 4.0 0.55 10.9 0.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4709 PF15821.5 EGF78991.1 - 0.056 13.7 3.0 0.096 13.0 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) GAS PF13851.6 EGF78991.1 - 0.077 12.3 6.7 0.13 11.6 6.7 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding LPP PF04728.13 EGF78991.1 - 0.15 12.5 2.2 0.59 10.6 0.2 2.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Spc7 PF08317.11 EGF78991.1 - 0.17 10.7 4.3 0.23 10.3 4.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 EGF78991.1 - 0.29 11.4 4.4 1.1 9.5 4.5 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMF_TATA_bd PF12325.8 EGF78991.1 - 0.33 11.2 6.9 2.8 8.2 1.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.13 EGF78991.1 - 2.1 9.1 6.7 7.7 7.3 4.9 2.1 1 1 1 2 2 2 0 Occludin homology domain HALZ PF02183.18 EGF78991.1 - 2.9 8.2 6.3 0.86 9.9 0.2 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 EGF78991.1 - 4.8 7.4 7.4 13 5.9 2.0 2.5 2 1 0 2 2 2 0 bZIP transcription factor Mod_r PF07200.13 EGF78992.1 - 0.0096 16.0 0.7 2 8.5 0.1 2.2 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein wnt PF00110.19 EGF78992.1 - 0.099 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 wnt family FAM184 PF15665.5 EGF78994.1 - 0.0048 16.7 2.3 0.0062 16.3 2.3 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Peptidase_M36 PF02128.15 EGF78995.1 - 1.1e-63 215.7 0.4 1.2e-63 215.5 0.4 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) MR_MLE_N PF02746.16 EGF78995.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PK PF00224.21 EGF78997.1 - 6.2e-105 350.9 1.8 2.4e-59 201.0 3.1 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 EGF78997.1 - 2.6e-14 53.4 0.0 6.2e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGF78997.1 - 0.12 11.5 0.4 0.43 9.7 0.1 1.8 1 1 1 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family SPC22 PF04573.12 EGF78998.1 - 4.2e-43 146.8 0.7 4.8e-43 146.6 0.7 1.0 1 0 0 1 1 1 1 Signal peptidase subunit adh_short PF00106.25 EGF78999.1 - 8.1e-41 139.6 0.1 1.1e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF78999.1 - 1.1e-21 77.5 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF78999.1 - 0.0087 16.0 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 KR domain SIS PF01380.22 EGF78999.1 - 0.042 13.7 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 SIS domain CENP-Q PF13094.6 EGF79000.1 - 0.0072 16.5 0.1 0.023 14.9 0.1 1.8 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GP20 PF06810.11 EGF79000.1 - 0.11 12.3 2.1 0.23 11.3 2.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Glyco_tranf_2_3 PF13641.6 EGF79001.1 - 0.0044 16.9 0.0 0.0087 16.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGF79001.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4162 PF13732.6 EGF79001.1 - 0.16 12.7 0.0 0.53 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) Asp PF00026.23 EGF79003.1 - 3e-13 49.9 0.0 1.1e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79003.1 - 2.9e-05 23.9 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF1539 PF07560.11 EGF79005.1 - 0.036 14.2 3.0 0.11 12.5 0.3 3.0 2 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) FidL_like PF15941.5 EGF79005.1 - 1.7 9.1 8.9 27 5.3 0.4 4.4 4 0 0 4 4 4 0 FidL-like putative membrane protein DUF1539 PF07560.11 EGF79006.1 - 0.0023 18.0 6.1 2.7 8.1 0.1 3.7 2 2 2 4 4 4 2 Domain of Unknown Function (DUF1539) BET PF17035.5 EGF79006.1 - 0.0044 17.2 5.7 0.61 10.3 0.5 3.0 3 0 0 3 3 3 2 Bromodomain extra-terminal - transcription regulation Fis1_TPR_N PF14852.6 EGF79006.1 - 0.034 13.8 0.7 4.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat EpuA PF11772.8 EGF79006.1 - 0.6 9.8 5.9 16 5.2 0.0 3.9 5 0 0 5 5 5 0 DNA-directed RNA polymerase subunit beta MADF_DNA_bdg PF10545.9 EGF79006.1 - 2.9 8.3 7.3 3 8.2 2.0 3.4 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4246 PF14033.6 EGF79007.1 - 3.6e-29 102.2 0.0 4.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4736 PF15883.5 EGF79010.1 - 0.021 14.5 1.6 0.46 10.2 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) DUF1539 PF07560.11 EGF79010.1 - 0.24 11.5 6.5 13 5.9 3.6 3.1 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1539) DUF2115 PF09888.9 EGF79010.1 - 2.2 8.8 8.2 1.4 9.4 1.4 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Dimer_Tnp_hAT PF05699.14 EGF79011.1 - 6.4e-20 70.7 0.2 7e-20 70.6 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FA_desaturase PF00487.24 EGF79014.1 - 7e-27 94.9 28.8 7e-27 94.9 28.8 2.2 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EGF79014.1 - 1.2e-10 41.8 0.3 2.2e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Methyltransf_11 PF08241.12 EGF79015.1 - 9.7e-16 58.2 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF79015.1 - 1.3e-14 54.4 0.0 2e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF79015.1 - 3.9e-14 53.1 0.0 7.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF79015.1 - 5.2e-11 42.6 0.0 9.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF79015.1 - 9.5e-11 42.3 0.0 2.5e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF79015.1 - 1.5e-06 27.8 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGF79015.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGF79015.1 - 0.067 13.0 0.0 0.3 10.9 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EGF79015.1 - 0.23 10.0 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Prefoldin_2 PF01920.20 EGF79016.1 - 6.3e-23 80.8 4.2 7.1e-23 80.6 4.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit T4SS PF07996.11 EGF79016.1 - 0.0025 18.2 0.8 0.0065 16.9 0.8 1.6 1 1 0 1 1 1 1 Type IV secretion system proteins Tup_N PF08581.10 EGF79016.1 - 0.018 15.4 2.0 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 Tup N-terminal BLOC1_2 PF10046.9 EGF79016.1 - 0.047 14.0 2.4 0.35 11.2 0.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 EGF79016.1 - 0.2 12.4 2.2 11 6.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Thioredoxin PF00085.20 EGF79017.1 - 3.1e-45 152.4 1.2 4e-25 87.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGF79017.1 - 3.8e-22 79.1 0.0 4.4e-12 46.3 0.0 3.4 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGF79017.1 - 4.3e-11 43.0 1.8 0.012 16.0 0.0 4.5 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.6 EGF79017.1 - 1.1e-09 38.3 0.2 0.00082 19.5 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGF79017.1 - 4.7e-08 33.4 1.9 0.00013 22.4 0.1 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGF79017.1 - 3.5e-07 30.0 0.2 0.00065 19.5 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.6 EGF79017.1 - 7.2e-06 26.0 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EGF79017.1 - 2.9e-05 23.6 0.7 0.22 10.8 0.0 3.2 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EGF79017.1 - 0.00093 19.2 0.1 0.0054 16.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.21 EGF79017.1 - 0.0027 17.6 0.3 0.61 10.0 0.0 2.7 2 0 0 2 2 2 1 AhpC/TSA family Glutaredoxin PF00462.24 EGF79017.1 - 0.64 10.3 2.1 5.9 7.2 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin Baculo_F PF12259.8 EGF79018.1 - 0.092 11.3 1.9 0.17 10.4 1.9 1.4 1 0 0 1 1 1 0 Baculovirus F protein DUF1128 PF06569.11 EGF79019.1 - 0.13 12.3 7.0 0.25 11.3 0.3 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) DUF641 PF04859.12 EGF79019.1 - 0.61 10.4 0.0 0.61 10.4 0.0 6.8 4 2 2 7 7 7 0 Plant protein of unknown function (DUF641) GCS PF03074.16 EGF79020.1 - 1.5e-161 537.9 0.0 2.2e-161 537.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase Pkinase PF00069.25 EGF79021.1 - 1.8e-62 211.1 0.0 2.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79021.1 - 7.8e-49 166.3 0.0 9.7e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF79021.1 - 2.5e-05 23.2 0.0 3.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGF79021.1 - 0.14 11.0 0.0 1.3 7.9 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Urb2 PF10441.9 EGF79022.1 - 3.6e-42 144.7 0.1 3.6e-42 144.7 0.1 4.1 5 0 0 5 5 5 1 Urb2/Npa2 family Peptidase_M27 PF01742.17 EGF79022.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease UCH PF00443.29 EGF79022.1 - 0.94 8.9 2.7 4 6.8 2.7 2.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WD40_3 PF15911.5 EGF79023.1 - 2.3e-17 62.7 0.0 8e-17 61.0 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGF79023.1 - 2.8e-10 39.8 9.3 0.0064 15.6 3.9 5.1 5 1 0 5 5 5 3 Coatomer WD associated region ANAPC4_WD40 PF12894.7 EGF79023.1 - 5.6e-10 39.4 0.1 0.00016 21.9 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EGF79023.1 - 3.2e-06 25.5 0.0 0.009 14.1 0.0 2.6 1 1 1 2 2 2 2 IKI3 family Clathrin PF00637.20 EGF79023.1 - 3.3e-06 27.0 5.4 0.0029 17.5 1.4 5.0 3 1 2 5 5 5 2 Region in Clathrin and VPS WD40 PF00400.32 EGF79023.1 - 1.3e-05 25.8 0.7 0.8 10.7 0.0 5.1 4 0 0 4 4 4 1 WD domain, G-beta repeat eIF2A PF08662.11 EGF79023.1 - 0.00024 21.1 0.0 0.00076 19.4 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPR_14 PF13428.6 EGF79023.1 - 0.24 12.3 14.5 33 5.7 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 EGF79023.1 - 0.27 11.3 6.8 1.4 9.0 6.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon ACPS PF01648.20 EGF79026.1 - 3.2e-10 40.1 0.0 6.6e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RRM_1 PF00076.22 EGF79027.1 - 1.2e-57 191.6 1.0 1.6e-18 66.3 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EGF79027.1 - 0.016 15.0 1.3 7.2 6.4 0.1 3.6 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain SET_assoc PF11767.8 EGF79027.1 - 0.053 13.2 0.1 23 4.7 0.0 3.9 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated Glyco_hydro_26 PF02156.15 EGF79028.1 - 2.7e-05 23.8 0.1 0.0057 16.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 EGF79028.1 - 0.24 11.0 0.1 0.51 9.9 0.1 1.5 1 0 0 1 1 1 0 EF hand Asp PF00026.23 EGF79029.1 - 2.4e-95 319.6 0.0 3e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF79029.1 - 6.4e-14 52.6 2.0 1.5e-07 31.8 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF79029.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF2870 PF11069.8 EGF79030.1 - 0.046 14.1 1.5 0.25 11.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Tannase PF07519.11 EGF79030.1 - 0.08 11.8 0.9 1.7 7.5 0.1 2.0 1 1 1 2 2 2 0 Tannase and feruloyl esterase RRM_1 PF00076.22 EGF79031.1 - 2e-16 59.6 0.0 2.6e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGF79031.1 - 1.8e-09 38.0 0.2 3.3e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EGF79031.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Lactamase_B_6 PF16661.5 EGF79032.1 - 1.2e-60 204.2 0.3 2.5e-60 203.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EGF79032.1 - 1e-18 67.6 0.0 2.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.6 EGF79032.1 - 1.2e-14 54.9 0.2 1.2e-14 54.9 0.2 1.6 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EGF79032.1 - 1.7e-12 47.1 0.0 4.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGF79032.1 - 8e-10 39.1 0.0 3.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGF79032.1 - 1e-06 28.4 0.3 1.9e-06 27.5 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF79032.1 - 0.0042 17.0 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Methyltr_RsmB-F PF01189.17 EGF79033.1 - 1.7e-26 93.1 0.0 3.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF1149 PF06619.11 EGF79033.1 - 0.015 15.6 0.3 9 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1149) FtsJ PF01728.19 EGF79033.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 EGF79033.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DUF2183 PF09949.9 EGF79034.1 - 1.5e-25 89.4 0.1 2.7e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EGF79034.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Phage_Mu_Gam PF07352.12 EGF79034.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein PPR_2 PF13041.6 EGF79035.1 - 5.6e-50 167.3 1.3 2e-14 53.5 0.1 7.9 5 2 4 9 9 9 5 PPR repeat family PPR PF01535.20 EGF79035.1 - 4.6e-36 120.5 6.8 4e-06 26.7 0.0 9.1 9 1 0 9 9 9 6 PPR repeat PPR_3 PF13812.6 EGF79035.1 - 2.6e-34 117.1 1.4 7.5e-12 45.1 0.0 5.8 4 2 3 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF79035.1 - 6.8e-34 115.3 0.3 1.2e-07 31.3 0.0 8.1 8 1 0 8 8 8 5 PPR repeat PPR_long PF17177.4 EGF79035.1 - 9.4e-25 87.2 1.3 1.8e-12 47.1 0.1 4.1 1 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EGF79035.1 - 1.4e-05 25.5 1.6 0.36 11.2 0.0 3.6 3 0 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 EGF79035.1 - 0.024 13.5 5.4 2.9 6.7 0.0 4.4 3 1 2 5 5 5 0 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 EGF79035.1 - 3.3 7.6 7.2 8.9 6.2 0.3 3.8 3 1 1 4 4 4 0 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 EGF79037.1 - 8.4e-169 562.3 0.0 3.4e-167 557.0 0.0 2.3 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGF79037.1 - 8.1e-39 130.9 12.7 4.2e-08 33.7 0.3 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79037.1 - 1e-10 41.8 0.4 0.058 13.7 0.0 6.9 3 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGF79037.1 - 4.1e-05 23.6 0.2 2.7 8.1 0.0 4.8 1 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EGF79037.1 - 0.0021 16.8 2.9 1.5 7.4 0.1 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Type_III_YscG PF09477.10 EGF79037.1 - 0.092 12.8 0.1 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) PDEase_I PF00233.19 EGF79038.1 - 1.4e-57 195.2 0.1 1.6e-57 195.0 0.1 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Iso_dh PF00180.20 EGF79039.1 - 4.9e-78 262.7 0.0 6.4e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.28 EGF79040.1 - 5.3e-21 75.7 0.4 5.3e-21 75.7 0.4 3.0 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 EGF79040.1 - 0.00028 20.6 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KRTAP PF11759.8 EGF79040.1 - 2.4 8.7 6.5 5.1 7.7 6.5 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Arm PF00514.23 EGF79042.1 - 0.18 11.9 3.5 27 5.0 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 EGF79043.1 - 2.5e-76 256.5 0.0 3e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79043.1 - 1.8e-43 148.7 0.0 2.3e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF79043.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF79043.1 - 0.00031 19.8 0.6 0.00046 19.2 0.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGF79043.1 - 0.0077 15.6 0.1 0.019 14.3 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF79043.1 - 0.0097 15.5 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Asp PF00026.23 EGF79044.1 - 2.4e-95 319.6 0.0 3.1e-95 319.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF79044.1 - 6.4e-14 52.6 2.0 1.5e-07 31.8 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF79044.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal MAT1 PF06391.13 EGF79045.1 - 0.21 11.4 2.7 0.32 10.8 2.7 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 7tm_3 PF00003.22 EGF79047.1 - 1.3e-32 113.5 14.7 1.6e-32 113.1 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2976 PF11190.8 EGF79047.1 - 0.58 10.0 3.5 0.79 9.6 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF996 PF06195.13 EGF79047.1 - 0.79 10.0 11.7 28 5.0 6.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF996) DUF3054 PF11255.8 EGF79047.1 - 1.4 9.4 6.9 1.6 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) DUF4203 PF13886.6 EGF79047.1 - 4.6 6.8 18.5 0.41 10.3 13.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4203) EF-hand_7 PF13499.6 EGF79048.1 - 0.028 14.9 0.2 54 4.3 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain pair Nse4_C PF08743.10 EGF79049.1 - 8.5e-30 102.9 0.2 2.8e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGF79049.1 - 6.9e-12 45.3 0.3 1.4e-11 44.3 0.3 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4272 PF14094.6 EGF79050.1 - 6.1e-05 22.4 4.2 0.00014 21.2 0.3 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4272) DNA_pol_E_B PF04042.16 EGF79051.1 - 1.3e-31 109.6 0.0 2e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EGF79051.1 - 2.2e-09 37.7 0.0 3.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal PMT PF02366.18 EGF79052.1 - 1.2e-67 228.1 12.9 3e-56 190.8 4.6 2.9 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGF79052.1 - 1.4e-59 201.0 14.6 1.4e-59 201.0 14.6 3.3 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGF79052.1 - 3.7e-11 43.2 1.2 7.4e-11 42.2 1.2 1.5 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EGF79052.1 - 6e-06 26.6 7.7 6e-06 26.6 7.7 3.3 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase LSM PF01423.22 EGF79053.1 - 4.9e-18 64.6 0.3 7.1e-18 64.1 0.3 1.3 1 0 0 1 1 1 1 LSM domain Radical_SAM_C PF16199.5 EGF79054.1 - 8e-31 105.9 0.1 4.6e-30 103.5 0.0 2.1 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGF79054.1 - 5.3e-17 62.7 0.4 4.9e-16 59.6 0.1 2.5 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGF79054.1 - 2.6e-10 40.5 0.0 4.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF79054.1 - 5e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF79054.1 - 0.00036 20.9 0.0 0.00075 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF79054.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein AAA PF00004.29 EGF79055.1 - 1.7e-45 154.7 0.1 5.4e-45 153.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGF79055.1 - 1.9e-09 37.9 0.0 1.8e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EGF79055.1 - 7.1e-09 35.5 0.0 4.6e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGF79055.1 - 9.2e-09 35.4 0.1 2.6e-08 33.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF79055.1 - 4.7e-08 33.6 0.2 2.2e-05 24.9 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 EGF79055.1 - 2.8e-06 27.0 0.0 7.5e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGF79055.1 - 3.5e-05 24.1 1.0 0.006 16.9 1.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGF79055.1 - 4.3e-05 22.8 0.0 8.4e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TsaE PF02367.17 EGF79055.1 - 0.00012 22.1 0.0 0.01 15.8 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EGF79055.1 - 0.00026 20.9 0.1 0.001 19.0 0.0 2.0 3 0 0 3 3 2 1 NTPase AAA_14 PF13173.6 EGF79055.1 - 0.00027 21.0 0.0 0.00089 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGF79055.1 - 0.00041 20.9 0.0 0.0014 19.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EGF79055.1 - 0.00043 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGF79055.1 - 0.00046 20.4 0.0 0.0031 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGF79055.1 - 0.0021 17.6 0.1 0.014 15.0 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGF79055.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGF79055.1 - 0.0033 17.8 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 EGF79055.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGF79055.1 - 0.006 16.3 0.1 0.015 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGF79055.1 - 0.0061 15.8 0.1 0.018 14.3 0.0 1.8 2 1 0 2 2 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGF79055.1 - 0.0083 15.5 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EGF79055.1 - 0.0093 15.4 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EGF79055.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGF79055.1 - 0.011 15.4 0.1 0.19 11.4 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGF79055.1 - 0.015 15.0 0.0 0.057 13.2 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EGF79055.1 - 0.016 15.1 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 EGF79055.1 - 0.023 14.6 1.0 0.41 10.5 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGF79055.1 - 0.028 14.7 0.2 0.14 12.5 0.1 2.2 3 0 0 3 3 1 0 AAA domain AFG1_ATPase PF03969.16 EGF79055.1 - 0.035 13.0 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase ATPase PF06745.13 EGF79055.1 - 0.038 13.3 0.1 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.6 EGF79055.1 - 0.041 13.7 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGF79055.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 EGF79055.1 - 0.063 12.9 1.7 0.19 11.3 0.1 2.3 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGF79055.1 - 0.11 13.0 0.1 0.35 11.4 0.0 2.1 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 EGF79055.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGF79055.1 - 0.29 11.6 2.9 1 9.8 0.0 2.4 2 1 0 2 2 1 0 AAA domain CAGE1 PF15066.6 EGF79055.1 - 0.63 8.7 4.8 0.95 8.1 4.8 1.2 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family BCDHK_Adom3 PF10436.9 EGF79056.1 - 1.2e-35 122.8 0.0 1.8e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGF79056.1 - 3.2e-11 43.7 0.1 1e-10 42.1 0.1 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGF79056.1 - 2.5e-05 24.1 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tfb4 PF03850.14 EGF79057.1 - 8.8e-23 81.2 0.0 2.2e-21 76.6 0.0 2.0 1 1 0 1 1 1 1 Transcription factor Tfb4 BSD PF03909.17 EGF79060.1 - 7.7e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 BSD domain Nas2_N PF18265.1 EGF79061.1 - 8.6e-28 96.1 0.3 1.4e-27 95.4 0.3 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EGF79061.1 - 2.1e-06 27.5 0.0 5.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EGF79061.1 - 1.7e-05 25.1 0.2 8.2e-05 22.9 0.0 2.2 2 1 1 3 3 3 1 PDZ domain GRASP55_65 PF04495.14 EGF79061.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.6 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF29 PF01724.16 EGF79061.1 - 0.012 15.8 0.2 0.023 14.9 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 MOR2-PAG1_N PF14222.6 EGF79062.1 - 1e-18 67.6 0.1 2.1e-17 63.3 0.1 2.8 1 1 0 1 1 1 1 Cell morphogenesis N-terminal IQ PF00612.27 EGF79063.1 - 1.6e-07 30.5 5.6 0.00064 19.3 0.0 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif HMMR_N PF15905.5 EGF79063.1 - 0.014 14.9 0.6 0.014 14.9 0.6 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Plk4_PB2 PF18409.1 EGF79063.1 - 0.44 11.3 2.3 20 5.9 0.3 2.7 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 UPF0172 PF03665.13 EGF79064.1 - 6.8e-47 160.0 0.1 8e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EGF79064.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WD40 PF00400.32 EGF79065.1 - 1e-11 45.1 9.3 0.012 16.4 0.3 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79065.1 - 0.00018 21.7 2.4 13 6.2 0.0 5.8 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EGF79065.1 - 0.0012 18.2 0.0 0.034 13.4 0.0 2.4 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller muHD PF10291.9 EGF79066.1 - 9.3e-29 100.7 0.0 3.7e-28 98.7 0.0 1.9 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EGF79066.1 - 5.8e-07 29.7 0.5 7.6e-05 22.9 0.0 3.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain CAF1A PF12253.8 EGF79066.1 - 0.056 13.6 0.3 0.46 10.7 0.0 2.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A MRG PF05712.13 EGF79067.1 - 1.8e-53 180.8 0.8 2.6e-53 180.3 0.8 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGF79067.1 - 1.1e-07 31.6 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EGF79067.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FHA PF00498.26 EGF79068.1 - 1.5e-18 66.9 0.3 3.9e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGF79068.1 - 1.1e-07 32.0 0.0 4e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain dsrm PF00035.26 EGF79068.1 - 2.3e-06 28.2 0.1 7.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 EGF79068.1 - 2.8e-05 24.2 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Dynactin_p22 PF07426.11 EGF79068.1 - 0.03 14.2 8.1 0.057 13.3 8.1 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Syntaxin_2 PF14523.6 EGF79068.1 - 0.12 12.8 6.7 0.26 11.7 6.7 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DUF4258 PF14076.6 EGF79068.1 - 0.24 11.8 0.6 20 5.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Chrome_Resist PF09828.9 EGF79068.1 - 0.33 11.4 1.8 0.92 10.0 0.8 2.2 2 0 0 2 2 2 0 Chromate resistance exported protein XhlA PF10779.9 EGF79068.1 - 3.3 8.0 4.5 8.6 6.7 4.3 1.8 1 1 0 1 1 1 0 Haemolysin XhlA TMPIT PF07851.13 EGF79068.1 - 8.9 5.5 7.9 15 4.7 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein HEAT PF02985.22 EGF79070.1 - 1.6e-16 59.0 7.8 0.0011 19.0 0.0 9.1 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 EGF79070.1 - 5.8e-15 55.4 6.4 7.2e-09 36.0 0.0 7.3 6 1 0 6 6 6 1 HEAT-like repeat IBN_N PF03810.19 EGF79070.1 - 1.3e-10 41.1 1.8 8.7e-10 38.4 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EGF79070.1 - 3.1e-07 30.7 2.6 0.0011 19.3 0.0 5.6 3 2 3 6 6 6 2 HEAT repeats RIX1 PF08167.12 EGF79070.1 - 2.1e-06 27.6 1.0 0.22 11.3 0.0 4.8 4 1 2 6 6 6 2 rRNA processing/ribosome biogenesis Arm PF00514.23 EGF79070.1 - 6.5e-06 26.0 5.7 0.0038 17.2 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGF79070.1 - 4.1e-05 23.7 0.2 0.0074 16.3 0.0 3.4 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 EGF79070.1 - 0.0013 18.4 3.3 0.4 10.2 0.0 3.7 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 EGF79070.1 - 0.0017 18.9 4.4 9.8 6.8 0.9 5.3 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGF79070.1 - 0.0041 16.7 6.1 0.73 9.4 0.1 4.6 3 2 2 6 6 6 2 CLASP N terminal TIP120 PF08623.10 EGF79070.1 - 0.0056 16.5 1.8 0.91 9.3 0.0 3.8 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) UPF0016 PF01169.19 EGF79071.1 - 1.8e-41 140.3 22.6 1.5e-21 76.5 7.6 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4131 PF13567.6 EGF79071.1 - 2.5 7.7 6.7 26 4.4 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Bestrophin PF01062.21 EGF79072.1 - 2e-31 109.5 2.7 1.7e-18 67.0 0.2 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF1548 PF07579.11 EGF79072.1 - 0.035 14.4 0.5 0.079 13.3 0.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Zip PF02535.22 EGF79073.1 - 1.1e-50 172.8 26.0 2.1e-50 171.9 26.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter RhodobacterPufX PF11511.8 EGF79073.1 - 0.15 11.6 2.0 0.26 10.9 0.0 2.4 3 0 0 3 3 3 0 Intrinsic membrane protein PufX CPP1-like PF11833.8 EGF79073.1 - 4.1 7.0 10.2 0.38 10.4 3.9 2.3 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Brr6_like_C_C PF10104.9 EGF79074.1 - 7.2e-26 90.5 2.6 7.8e-26 90.4 2.6 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain EXS PF03124.14 EGF79074.1 - 0.0015 18.0 0.1 0.0015 17.9 0.1 1.0 1 0 0 1 1 1 1 EXS family DUF1201 PF06716.11 EGF79074.1 - 0.0074 16.3 1.1 0.011 15.7 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) SieB PF14163.6 EGF79074.1 - 0.099 12.1 0.6 0.12 11.9 0.6 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B CENP-T_C PF15511.6 EGF79075.1 - 2.8e-08 33.8 0.1 3.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EGF79075.1 - 6.4e-05 23.0 0.1 9.3e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGF79075.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGF79075.1 - 0.00021 21.6 0.2 0.00024 21.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF79075.1 - 0.00039 20.7 0.1 0.00073 19.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGF79075.1 - 0.022 14.8 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGF79075.1 - 0.063 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EGF79075.1 - 0.18 12.3 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Actin PF00022.19 EGF79076.1 - 1.4e-133 445.5 0.0 1.5e-133 445.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGF79076.1 - 0.00012 21.1 0.0 0.16 10.8 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein Snurportin1 PF11538.8 EGF79077.1 - 6e-10 39.1 7.6 1.1e-09 38.4 7.6 1.4 1 0 0 1 1 1 1 Snurportin1 RasGEF PF00617.19 EGF79078.1 - 3.8e-51 173.8 1.8 6.3e-51 173.1 1.8 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGF79078.1 - 4.9e-13 49.2 0.0 1.2e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SQS_PSY PF00494.19 EGF79079.1 - 8.1e-54 182.9 0.0 9.9e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase PIP5K PF01504.18 EGF79080.1 - 2.9e-44 151.3 0.1 3.2e-35 121.7 0.2 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Aminotran_1_2 PF00155.21 EGF79082.1 - 5.5e-61 206.7 0.0 6.2e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGF79082.1 - 0.0002 20.7 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGF79082.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGF79082.1 - 0.0031 16.9 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGF79082.1 - 0.0067 15.0 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TSNAXIP1_N PF15739.5 EGF79083.1 - 5.1e-08 33.3 2.6 1.3e-07 31.9 2.6 1.7 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus ParB PF08775.10 EGF79083.1 - 0.011 16.2 0.5 0.011 16.2 0.5 2.4 2 1 1 3 3 3 0 ParB family CspB_prodomain PF18425.1 EGF79083.1 - 0.12 12.4 0.8 9.5 6.3 0.1 2.7 1 1 1 2 2 2 0 Csp protease B prodomain zf-met2 PF12907.7 EGF79084.1 - 8.1e-15 54.7 0.9 1.1e-14 54.2 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EGF79084.1 - 0.00018 22.3 10.9 0.00018 22.3 10.9 1.9 2 0 0 2 2 2 1 4F5 protein family zf-Di19 PF05605.12 EGF79084.1 - 0.18 12.1 1.0 1.2 9.5 1.0 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NPR3 PF03666.13 EGF79085.1 - 5.6e-99 332.0 0.6 7.5e-99 331.6 0.6 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Cation_ATPase_C PF00689.21 EGF79086.1 - 6.4e-43 146.6 4.9 6.4e-43 146.6 4.9 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGF79086.1 - 1.8e-33 115.6 6.3 1.8e-33 115.6 6.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGF79086.1 - 4e-19 69.7 0.4 2e-18 67.4 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGF79086.1 - 6.3e-16 58.2 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGF79086.1 - 1e-08 34.7 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF79086.1 - 0.0022 17.8 0.6 0.0091 15.8 0.7 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGF79086.1 - 0.21 11.3 1.6 1.2 9.0 0.2 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF572 PF04502.13 EGF79087.1 - 1.6e-72 245.0 6.8 1.8e-72 244.7 6.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF4661 PF15576.6 EGF79087.1 - 0.035 14.0 0.7 0.045 13.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-CSL PF05207.13 EGF79087.1 - 0.08 12.7 0.2 0.21 11.3 0.2 1.8 1 0 0 1 1 1 0 CSL zinc finger zf-ribbon_3 PF13248.6 EGF79087.1 - 0.13 11.7 0.6 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 EGF79087.1 - 0.29 11.3 2.6 8.7 6.5 0.4 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF2407_C PF13373.6 EGF79087.1 - 0.5 10.5 2.0 0.85 9.8 2.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain CpXC PF14353.6 EGF79087.1 - 0.7 10.0 4.0 15 5.6 4.3 2.6 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_4 PF13717.6 EGF79087.1 - 1.6 8.7 6.2 7.7 6.5 0.3 3.1 2 1 0 2 2 2 0 zinc-ribbon domain Ribosomal_L28e PF01778.17 EGF79088.1 - 2.8e-29 102.2 0.1 3.4e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family CAF1 PF04857.20 EGF79089.1 - 2.5e-19 69.6 0.1 2.8e-09 36.6 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease NDUF_C2 PF06374.11 EGF79090.1 - 2.8e-05 24.2 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Mon1 PF03164.14 EGF79091.1 - 0.048 12.7 0.6 1.6 7.7 0.1 2.1 2 0 0 2 2 2 0 Trafficking protein Mon1 TIM PF00121.18 EGF79092.1 - 1.9e-90 302.5 0.2 2.1e-90 302.3 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PGK PF00162.19 EGF79093.1 - 1.6e-147 491.4 0.2 1.8e-147 491.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ldh_1_N PF00056.23 EGF79094.1 - 3.5e-46 156.8 0.4 5.6e-46 156.1 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGF79094.1 - 1.1e-41 142.5 0.5 1.8e-41 141.9 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EGF79094.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGF79094.1 - 0.011 16.1 0.2 0.15 12.5 0.1 2.6 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain RabGAP-TBC PF00566.18 EGF79095.1 - 8.9e-27 94.1 2.0 1.2e-26 93.8 2.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SRP_TPR_like PF17004.5 EGF79095.1 - 0.02 14.9 0.2 0.041 13.9 0.2 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat Adeno_52K PF03052.15 EGF79095.1 - 0.056 12.9 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Ribosomal_L9_N PF01281.19 EGF79096.1 - 9.5e-12 44.3 0.2 1.6e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EGF79096.1 - 7.8e-09 35.9 0.1 1.3e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Rer1 PF03248.13 EGF79097.1 - 3.9e-71 238.3 1.7 4.3e-71 238.1 1.7 1.0 1 0 0 1 1 1 1 Rer1 family ThiF PF00899.21 EGF79098.1 - 3.2e-41 141.3 0.0 4.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGF79098.1 - 9.9e-06 25.8 1.4 0.00039 20.7 1.4 2.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGF79098.1 - 0.0028 17.9 0.5 0.0086 16.3 0.1 2.1 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EGF79098.1 - 0.0031 17.9 0.2 0.035 14.5 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 EGF79098.1 - 0.0066 16.1 0.2 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 EGF79098.1 - 0.0083 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGF79098.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EGF79098.1 - 0.02 14.2 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EGF79098.1 - 0.04 13.2 0.2 0.066 12.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGF79098.1 - 0.041 13.5 0.1 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1667 PF07892.11 EGF79098.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) WD40 PF00400.32 EGF79099.1 - 7.9e-12 45.5 11.7 0.00084 20.1 0.0 6.6 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79099.1 - 6.9e-09 35.9 0.2 0.018 15.3 0.0 4.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PHTB1_N PF14727.6 EGF79099.1 - 0.0033 16.9 0.2 0.011 15.1 0.1 1.9 2 0 0 2 2 2 1 PTHB1 N-terminus Coatomer_WDAD PF04053.14 EGF79099.1 - 0.0053 15.9 5.4 0.23 10.5 0.6 3.8 4 0 0 4 4 4 2 Coatomer WD associated region Clathrin PF00637.20 EGF79099.1 - 0.01 15.7 2.6 4.1 7.3 0.1 3.6 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_7 PF13176.6 EGF79099.1 - 0.013 15.5 3.6 2.8 8.2 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF79099.1 - 0.18 12.0 8.4 3.5 7.9 0.2 4.7 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGF79099.1 - 0.69 10.2 7.2 25 5.2 0.2 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EGF79100.1 - 1e-50 172.6 0.0 2.8e-43 148.2 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79100.1 - 6.5e-30 104.3 0.0 9.9e-27 93.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF79100.1 - 2.6e-08 33.5 0.0 5.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF79100.1 - 0.0035 17.3 0.1 0.038 13.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGF79100.1 - 0.024 13.7 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 L_protein_N PF15518.6 EGF79100.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus ABC_tran PF00005.27 EGF79103.1 - 1.7e-47 161.4 0.3 2.9e-24 86.1 0.0 4.2 3 2 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGF79103.1 - 3.9e-13 49.4 1.7 0.0019 17.6 0.0 4.5 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF79103.1 - 2.3e-12 47.4 0.4 0.0059 16.5 0.0 4.2 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF79103.1 - 1.2e-10 42.3 6.2 0.0004 20.9 4.5 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGF79103.1 - 3.4e-07 29.9 0.0 0.016 14.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGF79103.1 - 4.7e-07 29.9 1.1 0.019 14.9 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase Chromo PF00385.24 EGF79103.1 - 8.5e-07 28.8 1.4 1.9e-06 27.7 1.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EGF79103.1 - 8.6e-06 25.8 0.2 0.14 12.2 0.0 3.4 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGF79103.1 - 8.9e-06 26.0 0.0 0.047 14.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EGF79103.1 - 2.7e-05 24.0 0.0 1.4 8.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EGF79103.1 - 3.2e-05 24.4 0.0 0.037 14.4 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGF79103.1 - 8.6e-05 22.7 0.0 1.3 9.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain UME PF08064.13 EGF79103.1 - 0.0001 22.2 0.0 0.22 11.5 0.1 3.5 3 0 0 3 3 3 1 UME (NUC010) domain AAA_28 PF13521.6 EGF79103.1 - 0.00018 21.8 0.0 0.73 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGF79103.1 - 0.00018 22.0 0.0 0.17 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGF79103.1 - 0.0002 21.7 0.0 0.57 10.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase HEAT_EZ PF13513.6 EGF79103.1 - 0.00026 21.4 6.3 5.3 7.7 0.0 5.3 5 0 0 5 5 4 0 HEAT-like repeat AAA_15 PF13175.6 EGF79103.1 - 0.00036 20.4 3.3 0.62 9.7 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain HEAT PF02985.22 EGF79103.1 - 0.00037 20.5 0.3 1.5 9.3 0.0 4.3 4 0 0 4 4 3 1 HEAT repeat NACHT PF05729.12 EGF79103.1 - 0.00067 19.6 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGF79103.1 - 0.0011 19.4 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 EGF79103.1 - 0.0016 18.4 0.0 0.61 10.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGF79103.1 - 0.0017 17.9 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGF79103.1 - 0.0024 17.5 0.0 0.94 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EGF79103.1 - 0.0038 16.3 0.2 2.7 6.9 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 EGF79103.1 - 0.0047 16.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 EGF79103.1 - 0.0049 17.2 0.6 0.43 11.0 0.0 3.6 2 1 2 4 4 3 1 HEAT repeats ABC_tran_Xtn PF12848.7 EGF79103.1 - 0.0064 16.5 0.4 0.0064 16.5 0.4 2.8 4 0 0 4 4 1 1 ABC transporter AAA_24 PF13479.6 EGF79103.1 - 0.0065 16.2 0.0 2.6 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGF79103.1 - 0.0082 16.2 0.0 0.27 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain 4HB PF17947.1 EGF79103.1 - 0.01 15.9 0.1 0.039 14.0 0.1 2.0 1 0 0 1 1 1 0 Four helical bundle domain DUF87 PF01935.17 EGF79103.1 - 0.015 15.4 2.8 7.8 6.5 0.0 4.0 4 0 0 4 4 3 0 Helicase HerA, central domain Roc PF08477.13 EGF79103.1 - 0.047 13.9 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EGF79103.1 - 0.064 12.4 0.0 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NUC194 PF08163.12 EGF79103.1 - 0.095 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 NUC194 domain Phage_term_sma PF07141.11 EGF79103.1 - 0.1 12.3 0.9 0.25 11.1 0.9 1.5 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit PduV-EutP PF10662.9 EGF79103.1 - 0.12 12.1 0.0 6.4 6.5 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 EGF79103.1 - 0.15 11.9 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 EGF79103.1 - 0.15 12.1 0.1 12 6.0 0.2 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 EGF79103.1 - 0.19 11.5 2.1 10 5.8 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EGF79103.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.3 4 1 0 4 4 2 0 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EGF79104.1 - 5.8e-13 48.5 0.0 7.9e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF79104.1 - 0.029 14.0 0.0 2.2 7.9 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EGF79105.1 - 6.3e-64 211.9 1.0 5.1e-26 90.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EGF79105.1 - 0.033 14.6 1.0 0.099 13.0 0.2 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family eIF-5a PF01287.20 EGF79107.1 - 3.9e-27 94.2 0.2 5.4e-27 93.7 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGF79107.1 - 0.066 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Aph-1 PF06105.12 EGF79108.1 - 2.1e-43 148.4 24.6 2.4e-43 148.2 24.6 1.0 1 0 0 1 1 1 1 Aph-1 protein KH_1 PF00013.29 EGF79109.1 - 3e-06 26.9 0.3 6.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 KH domain Ribosomal_S17e PF00833.18 EGF79109.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S17 RRM_1 PF00076.22 EGF79110.1 - 0.00013 21.7 0.1 0.00036 20.3 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 EGF79111.1 - 1.2e-14 54.8 0.0 3.7e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF79111.1 - 3.4e-14 53.0 0.0 1e-13 51.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF79111.1 - 9.3e-14 52.0 0.0 2.9e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF79111.1 - 1.9e-11 44.5 0.0 4.5e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF79111.1 - 9.5e-07 28.7 0.0 2e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF79111.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Peptidase_M90 PF06167.12 EGF79111.1 - 0.0065 16.1 3.1 0.011 15.4 3.1 1.3 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 Methyltransf_24 PF13578.6 EGF79111.1 - 0.016 16.2 0.0 0.058 14.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 EGF79111.1 - 0.067 12.7 0.0 14 5.1 0.0 2.5 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 EGF79111.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SNF2_N PF00176.23 EGF79112.1 - 8.7e-73 245.0 0.0 1.7e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGF79112.1 - 7.1e-41 138.8 0.8 7.1e-41 138.8 0.8 3.0 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 EGF79112.1 - 3.8e-24 85.6 3.3 3.8e-24 85.6 3.3 3.6 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 EGF79112.1 - 8.5e-14 51.9 0.0 3.8e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF79112.1 - 3e-11 43.6 0.1 1.8e-10 41.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGF79112.1 - 3.4e-06 26.4 0.1 7.3e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGF79112.1 - 0.00079 19.2 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF79112.1 - 0.0012 19.1 0.1 0.11 12.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain DBINO PF13892.6 EGF79112.1 - 0.0049 17.2 1.3 0.0049 17.2 1.3 4.1 4 0 0 4 4 4 1 DNA-binding domain ERCC3_RAD25_C PF16203.5 EGF79112.1 - 0.049 12.8 1.3 0.06 12.5 0.1 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Orn_Arg_deC_N PF02784.16 EGF79113.1 - 2.6e-79 266.1 0.0 3.4e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGF79113.1 - 3.6e-19 68.8 0.0 5.4e-19 68.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF913 PF06025.12 EGF79113.1 - 0.0036 16.3 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Methyltransf_23 PF13489.6 EGF79114.1 - 7.2e-18 65.0 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF79114.1 - 5e-15 56.0 0.1 2.3e-14 53.9 0.0 2.1 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF79114.1 - 1.7e-13 51.1 0.0 3.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF79114.1 - 2.1e-11 44.3 0.0 4.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF79114.1 - 1.2e-06 28.5 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF79114.1 - 3.1e-05 23.6 0.0 7.9e-05 22.3 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGF79114.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 EGF79114.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EGF79114.1 - 0.011 15.2 0.0 0.74 9.3 0.0 2.5 2 1 0 2 2 2 0 Putative methyltransferase GerPC PF10737.9 EGF79114.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Spore germination protein GerPC tRNA_U5-meth_tr PF05958.11 EGF79114.1 - 0.035 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Atx10homo_assoc PF09759.9 EGF79115.1 - 0.074 13.1 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EGF79115.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HECT PF00632.25 EGF79116.1 - 1.4e-81 274.3 0.0 2e-81 273.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_S18 PF01084.20 EGF79117.1 - 2.1e-17 63.0 0.2 4e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 HSP70 PF00012.20 EGF79118.1 - 1.2e-81 274.8 21.6 4.2e-79 266.3 21.6 2.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF79118.1 - 0.00048 19.0 0.1 0.014 14.2 0.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein Thiolase_N PF00108.23 EGF79119.1 - 8.7e-77 258.0 0.1 5.6e-76 255.3 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF79119.1 - 4.2e-51 171.8 0.5 7.2e-51 171.0 0.5 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGF79119.1 - 0.00055 19.6 0.3 0.00055 19.6 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain GATase_6 PF13522.6 EGF79120.1 - 4.9e-16 59.1 0.0 1e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGF79120.1 - 1.2e-12 47.8 0.0 2.6e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGF79120.1 - 1.8e-06 27.6 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EGF79120.1 - 6.1e-05 22.1 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II WD40 PF00400.32 EGF79121.1 - 4.5e-19 68.4 23.9 0.00068 20.4 0.6 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79121.1 - 1.3e-07 31.8 6.9 0.0016 18.7 0.2 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF79121.1 - 0.0025 16.8 0.9 1.7 7.5 0.1 3.5 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein GYF_2 PF14237.6 EGF79121.1 - 0.06 13.2 0.8 4.2 7.3 0.0 2.9 3 0 0 3 3 3 0 GYF domain 2 Phi_1 PF04674.12 EGF79122.1 - 3.3e-31 108.6 5.1 9e-31 107.2 5.1 1.7 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region Flavin_Reduct PF01613.18 EGF79124.1 - 1.1e-38 132.8 0.5 1.7e-38 132.1 0.5 1.3 1 0 0 1 1 1 1 Flavin reductase like domain LLC1 PF14945.6 EGF79126.1 - 5.6e-13 49.5 2.2 2.6e-11 44.2 1.3 2.8 1 1 0 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.6 EGF79126.1 - 0.0062 17.2 1.2 0.025 15.3 0.5 2.2 2 1 1 3 3 3 1 FAM183A and FAM183B related eIF3_N PF09440.10 EGF79127.1 - 1.3e-42 145.4 8.1 3e-42 144.2 8.1 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGF79127.1 - 6.3e-17 62.0 0.1 1.7e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 PCI domain DUF771 PF05595.11 EGF79127.1 - 0.081 12.9 0.8 5.7 7.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF771) Tubulin PF00091.25 EGF79129.1 - 1.1e-49 169.3 0.0 1.9e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF79129.1 - 2.8e-20 72.8 0.0 7.3e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 EGF79129.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like tRNA-synt_2 PF00152.20 EGF79130.1 - 3.6e-69 233.2 0.0 4.5e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EGF79130.1 - 6.4e-07 29.1 0.1 0.033 13.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 EGF79130.1 - 2.2e-06 27.6 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain 14-3-3 PF00244.20 EGF79131.1 - 1.6e-106 354.8 2.5 1.9e-106 354.6 2.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Rad60-SLD PF11976.8 EGF79132.1 - 6e-21 74.1 0.0 7.2e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGF79132.1 - 3.8e-11 42.6 0.0 4.5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PC4 PF02229.16 EGF79133.1 - 1.8e-19 69.1 0.3 2.7e-19 68.5 0.3 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ATP-synt_DE_N PF02823.16 EGF79134.1 - 6.3e-16 58.1 0.0 8.8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 EGF79134.1 - 0.065 13.5 1.8 0.065 13.5 1.8 1.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Tyr-DNA_phospho PF06087.12 EGF79135.1 - 1.9e-52 178.6 0.5 3.4e-52 177.8 0.5 1.4 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase GATase_5 PF13507.6 EGF79136.1 - 2.8e-87 292.1 0.0 4e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGF79136.1 - 6.4e-42 143.3 0.2 1.4e-30 106.5 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGF79136.1 - 3.9e-29 101.0 0.0 7.1e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGF79136.1 - 2.3e-22 79.3 0.1 5.8e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain SH3_1 PF00018.28 EGF79137.1 - 1.1e-07 31.4 0.1 3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGF79137.1 - 2.1e-05 24.3 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF79137.1 - 0.008 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5021 PF16424.5 EGF79137.1 - 0.075 12.9 0.3 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5021) NAD_kinase PF01513.21 EGF79138.1 - 1.6e-78 263.9 0.0 2.5e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGF79138.1 - 0.002 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TPALS PF18178.1 EGF79138.1 - 0.0024 17.4 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 TIR- and PNP-associating SLOG family Pro_CA PF00484.19 EGF79139.1 - 9.4e-49 165.7 0.0 1.2e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Peptidase_S41 PF03572.18 EGF79141.1 - 4.3e-12 45.9 0.0 8.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 MxiM PF11441.8 EGF79141.1 - 0.043 14.1 0.5 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 Pilot protein MxiM SlyX PF04102.12 EGF79142.1 - 0.082 13.5 0.8 1.2 9.8 0.2 2.2 1 1 0 2 2 2 0 SlyX DUF3368 PF11848.8 EGF79142.1 - 0.17 11.7 0.6 0.87 9.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) TMF_TATA_bd PF12325.8 EGF79145.1 - 0.0068 16.6 0.6 2.3 8.5 0.0 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding EF-hand_12 PF17901.1 EGF79146.1 - 0.032 14.7 0.1 6.1 7.4 0.0 3.0 1 1 2 3 3 3 0 EF-hand fold domain HJURP_C PF12347.8 EGF79147.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Hormone_6 PF00236.18 EGF79148.1 - 0.003 17.5 0.5 0.0036 17.2 0.5 1.2 1 0 0 1 1 1 1 Glycoprotein hormone LIP PF03583.14 EGF79148.1 - 0.09 12.1 0.1 0.099 11.9 0.1 1.0 1 0 0 1 1 1 0 Secretory lipase MOZ_SAS PF01853.18 EGF79150.1 - 0.0033 17.1 0.0 0.0033 17.1 0.0 1.0 1 0 0 1 1 1 1 MOZ/SAS family Pyrophosphatase PF00719.19 EGF79154.1 - 0.012 15.4 0.6 0.015 15.1 0.6 1.1 1 0 0 1 1 1 0 Inorganic pyrophosphatase Asp PF00026.23 EGF79155.1 - 2.8e-11 43.4 0.0 3.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4201 PF13870.6 EGF79157.1 - 1.1e-05 25.3 11.2 1.5e-05 24.8 11.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 EGF79157.1 - 0.0003 21.0 4.5 0.0046 17.2 4.7 2.2 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Filament PF00038.21 EGF79157.1 - 0.00036 20.2 3.5 0.00049 19.8 3.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein FAM76 PF16046.5 EGF79157.1 - 0.00042 19.8 2.7 0.00059 19.3 2.7 1.2 1 0 0 1 1 1 1 FAM76 protein CEP209_CC5 PF16574.5 EGF79157.1 - 0.0007 19.8 1.0 0.0013 18.9 1.0 1.4 1 0 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 Sporozoite_P67 PF05642.11 EGF79157.1 - 0.001 17.3 1.9 0.0012 17.0 1.9 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Spc7 PF08317.11 EGF79157.1 - 0.0016 17.4 6.3 0.0022 17.0 6.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Macoilin PF09726.9 EGF79157.1 - 0.0018 16.9 5.5 0.0023 16.6 5.5 1.1 1 0 0 1 1 1 1 Macoilin family DUF812 PF05667.11 EGF79157.1 - 0.002 17.1 2.6 0.0023 16.9 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Cast PF10174.9 EGF79157.1 - 0.0022 16.3 4.4 0.0036 15.6 4.4 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.9 EGF79157.1 - 0.0028 16.8 2.9 0.0033 16.5 2.9 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 EGF79157.1 - 0.0047 17.3 7.7 0.0047 17.3 7.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EGF79157.1 - 0.0096 16.0 1.2 0.015 15.3 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MAD PF05557.13 EGF79157.1 - 0.014 13.8 10.3 0.017 13.5 10.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein TMPIT PF07851.13 EGF79157.1 - 0.015 14.6 4.2 0.02 14.2 4.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein BRE1 PF08647.11 EGF79157.1 - 0.018 15.1 10.9 0.025 14.6 10.9 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF496 PF04363.12 EGF79157.1 - 0.022 14.8 3.9 0.022 14.8 3.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF496) EzrA PF06160.12 EGF79157.1 - 0.024 12.8 5.4 0.03 12.5 5.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 EGF79157.1 - 0.026 12.5 3.6 0.036 12.0 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BST2 PF16716.5 EGF79157.1 - 0.032 14.8 2.3 0.032 14.8 2.3 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 HAP1_N PF04849.13 EGF79157.1 - 0.036 13.3 5.5 0.047 12.9 5.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region HIP1_clath_bdg PF16515.5 EGF79157.1 - 0.039 14.5 3.5 0.039 14.5 3.5 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Paramyx_P_V_C PF03210.13 EGF79157.1 - 0.04 13.7 0.5 0.04 13.7 0.5 1.8 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal DUF16 PF01519.16 EGF79157.1 - 0.041 14.4 1.7 0.071 13.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 IZUMO PF15005.6 EGF79157.1 - 0.046 14.3 1.4 0.068 13.7 1.4 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Spc29 PF17082.5 EGF79157.1 - 0.048 13.5 6.3 0.6 9.9 6.2 2.2 1 1 1 2 2 2 0 Spindle Pole Component 29 Calc_CGRP_IAPP PF00214.19 EGF79157.1 - 0.048 14.0 3.1 0.084 13.2 0.4 2.0 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family ATG16 PF08614.11 EGF79157.1 - 0.062 13.5 9.6 0.021 15.0 4.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EGF79157.1 - 0.065 13.0 5.3 0.069 12.9 3.7 1.8 1 1 2 3 3 3 0 Septum formation initiator Exonuc_VII_L PF02601.15 EGF79157.1 - 0.066 12.8 4.0 0.082 12.5 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DHR10 PF18595.1 EGF79157.1 - 0.077 13.1 4.0 0.12 12.4 4.0 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ADIP PF11559.8 EGF79157.1 - 0.23 11.6 10.9 0.46 10.6 10.0 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4806 PF16064.5 EGF79157.1 - 0.25 11.7 2.6 0.31 11.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) TMF_DNA_bd PF12329.8 EGF79157.1 - 0.27 11.3 12.0 0.1 12.6 8.6 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 EGF79157.1 - 0.28 11.3 6.6 0.11 12.5 1.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 EGF79157.1 - 0.41 10.9 8.0 0.64 10.2 8.0 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4404 PF14357.6 EGF79157.1 - 0.64 10.7 3.0 0.81 10.4 1.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) APG6_N PF17675.1 EGF79157.1 - 1 9.9 9.9 1.5 9.4 9.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 EGF79157.1 - 2.9 8.7 7.6 4.5 8.1 1.7 2.2 1 1 1 2 2 2 0 Occludin homology domain ZapB PF06005.12 EGF79157.1 - 7.6 7.1 9.3 6.5 7.3 6.1 2.3 1 1 1 2 2 2 0 Cell division protein ZapB FliD_N PF02465.18 EGF79157.1 - 7.7 7.3 16.5 2 9.2 3.0 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4246 PF14033.6 EGF79160.1 - 1.2e-59 202.6 0.0 1.5e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Peptidase_C98 PF15499.6 EGF79161.1 - 0.024 14.1 2.1 0.052 13.0 2.1 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CsiV PF10972.8 EGF79162.1 - 0.11 12.3 6.3 0.14 11.9 6.3 1.3 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV DUF4175 PF13779.6 EGF79162.1 - 0.18 9.7 17.1 0.22 9.4 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PP_kinase_N PF13089.6 EGF79163.1 - 5.5e-05 23.5 4.7 0.00019 21.7 0.9 2.2 1 1 1 2 2 2 1 Polyphosphate kinase N-terminal domain MIF4G_like_2 PF09090.11 EGF79163.1 - 0.001 18.6 2.4 0.0015 18.0 2.4 1.3 1 0 0 1 1 1 1 MIF4G like DUF4140 PF13600.6 EGF79163.1 - 0.018 15.5 6.5 8.5 6.9 6.5 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EGF79163.1 - 0.018 13.9 13.7 0.027 13.4 13.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 EGF79163.1 - 0.023 14.1 17.3 0.076 12.4 17.3 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding LUC7 PF03194.15 EGF79163.1 - 0.024 14.3 9.8 0.033 13.8 9.8 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF4407 PF14362.6 EGF79163.1 - 0.029 13.8 2.6 0.047 13.0 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pectate_lyase PF03211.13 EGF79163.1 - 0.058 12.9 0.7 0.12 11.9 0.5 1.6 2 0 0 2 2 2 0 Pectate lyase Exonuc_VII_L PF02601.15 EGF79163.1 - 0.087 12.4 3.7 0.11 12.0 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NHS PF15273.6 EGF79163.1 - 0.2 10.7 3.0 0.25 10.4 3.0 1.1 1 0 0 1 1 1 0 NHS-like MADF_DNA_bdg PF10545.9 EGF79163.1 - 0.33 11.3 4.2 0.56 10.6 3.5 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FapA PF03961.13 EGF79163.1 - 1.1 7.7 9.1 1.5 7.3 9.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_Maf PF03131.17 EGF79163.1 - 1.3 9.6 8.8 0.4 11.2 5.1 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor APG6_N PF17675.1 EGF79163.1 - 1.4 9.5 15.0 14 6.2 14.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Cdh1_DBD_1 PF18196.1 EGF79163.1 - 1.6 9.1 9.7 0.63 10.4 1.3 2.2 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF4446 PF14584.6 EGF79163.1 - 1.8 8.5 8.0 0.6 10.1 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DivIC PF04977.15 EGF79163.1 - 2.3 8.0 10.2 3.3 7.5 1.4 2.3 2 0 0 2 2 2 0 Septum formation initiator BRE1 PF08647.11 EGF79163.1 - 2.9 8.0 17.5 2 8.5 5.4 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-H PF05837.12 EGF79163.1 - 2.9 8.3 10.0 5.2 7.5 9.2 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Glyco_hydro_76 PF03663.14 EGF79164.1 - 4.4e-52 177.8 4.1 6e-52 177.4 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGF79164.1 - 1.6e-07 30.7 1.7 0.01 14.9 0.3 3.4 3 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 EGF79165.1 - 1.4e-35 123.5 2.2 1.5e-35 123.4 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 EGF79165.1 - 7.7e-05 22.3 0.4 0.069 12.7 0.1 2.2 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 EGF79165.1 - 7.8e-05 21.9 2.1 0.0021 17.2 0.1 2.1 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.20 EGF79165.1 - 0.00097 18.1 0.3 0.045 12.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_9 PF00759.19 EGF79165.1 - 0.018 14.5 1.0 0.025 14.0 0.6 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 9 Glyco_hydro_127 PF07944.12 EGF79165.1 - 0.021 13.3 0.4 0.11 11.0 0.4 1.8 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 UNC80 PF15778.5 EGF79166.1 - 0.018 14.6 0.2 0.079 12.6 0.0 1.9 2 0 0 2 2 2 0 Cation channel complex component UNC80 ADIP PF11559.8 EGF79167.1 - 4.8e-24 85.2 8.9 4.8e-24 85.2 8.9 3.1 2 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 EGF79167.1 - 0.78 9.8 7.8 0.63 10.1 0.8 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EGF79167.1 - 3.8 8.0 34.7 0.17 12.4 7.1 3.2 2 1 2 4 4 4 0 Apg6 coiled-coil region DUF1356 PF07092.12 EGF79168.1 - 0.057 12.7 0.1 0.097 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Neurensin PF14927.6 EGF79169.1 - 0.045 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Neurensin OPT PF03169.15 EGF79170.1 - 4.8e-122 408.7 48.0 5.5e-122 408.5 48.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gln-synt_N_2 PF16952.5 EGF79171.1 - 0.00068 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Hydrolase_4 PF12146.8 EGF79172.1 - 1.3e-08 34.4 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGF79172.1 - 2.3e-08 34.0 0.4 2.8e-07 30.4 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 EGF79172.1 - 0.058 13.3 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase Torsin PF06309.11 EGF79172.1 - 0.12 12.5 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Torsin Aminotran_1_2 PF00155.21 EGF79173.1 - 2.4e-19 69.8 0.0 2.9e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGF79173.1 - 2.6e-08 33.1 0.0 3.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Lactamase_B_2 PF12706.7 EGF79174.1 - 1.7e-21 76.7 0.0 2.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGF79174.1 - 3.7e-08 33.6 0.0 7.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily 2OG-FeII_Oxy_2 PF13532.6 EGF79175.1 - 2e-17 64.0 0.0 2.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.6 EGF79176.1 - 2.5e-50 171.2 2.3 2.9e-50 171.0 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF79176.1 - 2.1e-49 167.6 4.0 2.6e-49 167.4 4.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF79176.1 - 2.2e-09 37.5 1.4 2.8e-09 37.1 1.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF79176.1 - 0.0038 16.7 0.6 0.006 16.1 0.6 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HD PF01966.22 EGF79177.1 - 4.7e-12 46.2 0.2 9.4e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EGF79177.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase RsbU_N PF08673.10 EGF79177.1 - 0.07 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain F-box-like PF12937.7 EGF79178.1 - 2.7e-05 24.0 0.1 0.00012 21.9 0.1 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGF79178.1 - 0.0008 19.3 12.2 0.79 9.9 0.3 6.3 7 0 0 7 7 7 2 Leucine Rich repeat F-box PF00646.33 EGF79178.1 - 0.00081 19.2 0.2 0.082 12.8 0.0 2.8 2 0 0 2 2 2 1 F-box domain SAM_Ste50p PF09235.10 EGF79178.1 - 7.8 6.8 6.8 35 4.7 0.7 3.5 3 1 1 4 4 4 0 Ste50p, sterile alpha motif SHIPPO-rpt PF07004.12 EGF79179.1 - 6.1e-17 61.7 38.2 0.27 12.2 0.0 12.7 12 1 0 12 12 12 10 Sperm-tail PG-rich repeat Mur_ligase_M PF08245.12 EGF79180.1 - 1.9e-12 47.6 0.0 5.6e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain SurA_N_2 PF13623.6 EGF79180.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Lipoprotein_15 PF03640.15 EGF79180.1 - 0.23 11.0 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Secreted repeat of unknown function DUF908 PF06012.12 EGF79181.1 - 0.033 13.6 0.8 0.046 13.1 0.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DNA_binding_2 PF13724.6 EGF79181.1 - 0.99 9.9 3.9 1.2 9.6 0.0 2.6 2 1 1 3 3 3 0 DNA-binding domain Troponin PF00992.20 EGF79182.1 - 0.095 13.0 1.2 0.51 10.7 0.8 2.1 1 1 1 2 2 2 0 Troponin Baculo_PEP_N PF04512.12 EGF79182.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Ribonuclease_3 PF00636.26 EGF79183.1 - 1.7e-17 64.0 0.0 5.1e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF79183.1 - 4.5e-10 39.8 0.0 5.2e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like FGGY_C PF02782.16 EGF79184.1 - 2.3e-54 184.2 0.4 3e-54 183.8 0.4 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain bZIP_1 PF00170.21 EGF79185.1 - 2.1e-06 27.7 6.7 3.8e-06 26.9 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGF79185.1 - 4.7e-06 26.6 8.2 9.1e-06 25.7 8.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGF79185.1 - 0.0014 19.1 1.7 0.0023 18.4 1.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF724 PF05266.14 EGF79185.1 - 0.08 12.8 0.7 0.1 12.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Strep_his_triad PF04270.13 EGF79185.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Streptococcal histidine triad protein FGGY_N PF00370.21 EGF79186.1 - 5e-58 196.6 0.1 7.8e-48 163.2 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGF79186.1 - 6.8e-55 185.9 1.2 1.8e-54 184.5 0.7 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain bZIP_2 PF07716.15 EGF79187.1 - 1.9e-06 27.8 6.5 3.6e-06 27.0 6.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGF79187.1 - 3.2e-06 27.1 6.6 6.1e-06 26.2 6.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGF79187.1 - 0.0037 17.8 3.1 0.007 16.9 3.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 EGF79187.1 - 0.053 12.9 1.3 0.065 12.6 1.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF724 PF05266.14 EGF79187.1 - 0.084 12.7 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FGGY_N PF00370.21 EGF79188.1 - 5.3e-71 239.1 0.3 6.1e-71 238.8 0.3 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Bystin PF05291.11 EGF79190.1 - 2.5e-140 466.8 1.7 2.5e-140 466.8 1.7 1.4 2 0 0 2 2 2 1 Bystin Bud13 PF09736.9 EGF79190.1 - 0.022 15.1 5.4 0.041 14.3 5.4 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF4446 PF14584.6 EGF79190.1 - 0.029 14.4 0.5 0.029 14.4 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF3967 PF13152.6 EGF79190.1 - 1.3 8.9 6.4 0.33 10.8 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3967) Ribosomal_L13 PF00572.18 EGF79191.1 - 6.3e-49 165.4 0.2 7.6e-49 165.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Bac_globin PF01152.21 EGF79192.1 - 4.6e-17 62.3 0.0 5.4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 EGF79192.1 - 0.0011 18.8 0.0 0.0034 17.3 0.0 1.7 1 1 0 1 1 1 1 Protoglobin SRP54_N PF02881.19 EGF79192.1 - 0.079 13.2 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DNA_primase_S PF01896.19 EGF79193.1 - 1.2e-56 191.6 0.3 2.1e-56 190.7 0.2 1.5 2 0 0 2 2 2 1 DNA primase small subunit LUD_dom PF02589.15 EGF79193.1 - 0.23 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 LUD domain ATP_sub_h PF10775.9 EGF79194.1 - 1e-11 44.6 0.1 1.6e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ACOX PF01756.19 EGF79196.1 - 7.4e-45 152.7 0.0 1.4e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGF79196.1 - 3.2e-19 68.9 0.1 5.9e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EGF79196.1 - 5e-14 52.9 0.0 1.1e-13 51.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EGF79196.1 - 7.9e-08 32.6 0.1 2.4e-06 27.8 0.1 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PPR_2 PF13041.6 EGF79199.1 - 5.3e-19 68.1 1.3 0.00044 20.4 0.1 7.3 6 2 3 9 9 9 4 PPR repeat family PPR PF01535.20 EGF79199.1 - 1.4e-12 46.9 2.6 0.079 13.2 0.1 8.5 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 EGF79199.1 - 2.9e-08 33.7 0.3 0.32 11.1 0.0 5.6 5 1 0 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EGF79199.1 - 6.5e-07 28.9 0.7 0.018 14.4 0.0 3.4 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF5617 PF18493.1 EGF79199.1 - 0.0069 16.5 0.0 0.034 14.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5617) PPR_1 PF12854.7 EGF79199.1 - 0.1 12.3 5.5 32 4.3 0.0 5.4 7 0 0 7 7 7 0 PPR repeat MtN3_slv PF03083.16 EGF79200.1 - 9.3e-33 112.1 17.0 1.9e-16 59.8 5.9 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange ECSCR PF15820.5 EGF79200.1 - 0.011 15.6 0.3 0.047 13.5 0.2 2.0 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator MPC PF03650.13 EGF79200.1 - 0.014 15.5 0.8 5.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers MULE PF10551.9 EGF79200.1 - 0.084 13.3 1.6 0.11 12.9 0.5 1.9 2 0 0 2 2 2 0 MULE transposase domain DUF2418 PF10332.9 EGF79200.1 - 0.17 12.4 3.5 3.6 8.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF4199 PF13858.6 EGF79200.1 - 0.69 10.3 16.6 1.6 9.1 10.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4199) UPF0182 PF03699.13 EGF79200.1 - 3.8 5.5 7.6 4.8 5.2 7.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) UbiA PF01040.18 EGF79201.1 - 9.3e-56 188.9 21.9 1.2e-55 188.6 21.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Cation_ATPase_C PF00689.21 EGF79201.1 - 0.43 10.3 8.3 0.91 9.2 0.8 2.7 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF3668 PF12416.8 EGF79202.1 - 4.4e-30 105.2 0.1 1.4e-28 100.3 0.1 2.7 1 1 0 1 1 1 1 Cep120 protein C2 PF00168.30 EGF79202.1 - 0.0014 18.9 0.0 0.074 13.3 0.0 2.9 3 0 0 3 3 3 1 C2 domain DUF4497 PF14924.6 EGF79202.1 - 0.084 13.3 0.2 2 8.9 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4497) HrcA PF01628.21 EGF79202.1 - 3 7.7 7.4 2.1 8.2 5.3 1.8 1 1 0 1 1 1 0 HrcA protein C terminal domain WD40 PF00400.32 EGF79203.1 - 1.1e-38 130.5 26.6 6e-08 33.2 1.7 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.12 EGF79203.1 - 4.2e-20 72.0 0.1 7.3e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 EGF79203.1 - 2.9e-06 27.5 4.6 0.0038 17.5 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF79203.1 - 1.2e-05 24.2 13.1 0.005 15.6 0.5 4.3 1 1 3 5 5 5 2 Nucleoporin Nup120/160 Marek_SORF3 PF07153.11 EGF79203.1 - 0.019 14.3 0.2 1.3 8.3 0.0 2.6 2 1 1 3 3 3 0 Marek's disease-like virus SORF3 protein Lactonase PF10282.9 EGF79203.1 - 0.019 14.2 0.2 0.038 13.3 0.2 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller IF4E PF01652.18 EGF79204.1 - 1.5e-53 180.9 1.9 1.9e-53 180.5 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glycos_transf_2 PF00535.26 EGF79205.1 - 1.5e-24 86.7 0.0 1.9e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGF79205.1 - 4e-07 30.2 0.0 9.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGF79205.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGF79205.1 - 0.0061 17.0 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tcp10_C PF07202.13 EGF79206.1 - 5.6e-37 127.4 0.2 5.6e-37 127.4 0.2 2.8 3 0 0 3 3 3 1 T-complex protein 10 C-terminus ig PF00047.25 EGF79206.1 - 0.012 15.8 0.7 0.038 14.2 0.7 1.9 1 0 0 1 1 1 0 Immunoglobulin domain MORN_2 PF07661.13 EGF79206.1 - 0.055 13.7 0.5 13 6.4 0.0 4.4 5 1 1 6 6 6 0 MORN repeat variant TMF_DNA_bd PF12329.8 EGF79206.1 - 0.31 11.1 25.0 0.043 13.8 5.7 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 EGF79206.1 - 1.2 9.3 29.5 0.57 10.3 5.0 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 RRM_Rrp7 PF17799.1 EGF79207.1 - 0.011 15.5 0.9 0.15 11.9 0.2 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DCX PF03607.17 EGF79207.1 - 0.013 15.6 0.0 0.042 13.9 0.0 1.9 1 0 0 1 1 1 0 Doublecortin DED PF01335.21 EGF79207.1 - 0.3 11.4 2.3 0.55 10.6 0.1 2.5 3 1 0 3 3 3 0 Death effector domain Asp PF00026.23 EGF79209.1 - 1.4e-17 64.1 0.1 2.1e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79209.1 - 1e-05 25.4 0.2 5.2e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF2870 PF11069.8 EGF79210.1 - 0.0018 18.6 5.4 0.003 17.9 0.3 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2870) FBPase_2 PF06874.11 EGF79210.1 - 0.0037 15.6 0.5 0.0048 15.2 0.1 1.3 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Spectrin PF00435.21 EGF79210.1 - 0.022 15.2 4.2 1 9.9 0.9 2.3 2 0 0 2 2 2 0 Spectrin repeat Phage_GP20 PF06810.11 EGF79210.1 - 0.024 14.4 5.1 0.96 9.2 0.4 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 EGF79210.1 - 0.026 14.8 3.5 0.56 10.5 0.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spem1 PF15670.5 EGF79210.1 - 4.6 6.7 7.9 0.82 9.2 3.2 2.0 1 1 0 2 2 2 0 Spermatid maturation protein 1 Pneumo_att_G PF05539.11 EGF79210.1 - 5.8 6.4 10.1 7.9 6.0 10.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Pkinase PF00069.25 EGF79216.1 - 4.9e-55 186.7 0.0 5.9e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79216.1 - 2.8e-27 95.6 0.0 1.1e-26 93.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF79216.1 - 0.0024 17.3 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF79216.1 - 0.0032 17.4 0.0 0.0071 16.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGF79216.1 - 0.0047 16.6 0.0 0.14 11.8 0.0 2.2 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGF79216.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF79216.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EGF79216.1 - 0.045 12.7 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Peptidase_C71 PF12386.8 EGF79216.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei LuxC PF05893.14 EGF79216.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) YukC PF10140.9 EGF79216.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC BSD PF03909.17 EGF79216.1 - 0.14 12.1 0.2 18 5.4 0.0 2.4 2 0 0 2 2 2 0 BSD domain Tyr-DNA_phospho PF06087.12 EGF79217.1 - 0.078 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Ribosomal_S8 PF00410.19 EGF79217.1 - 0.096 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S8 TLD PF07534.16 EGF79218.1 - 2.1e-34 118.7 1.2 3.5e-34 118.0 1.2 1.4 1 0 0 1 1 1 1 TLD MMM1 PF10296.9 EGF79219.1 - 4e-12 45.9 0.5 4.1e-05 22.8 0.0 3.1 2 1 1 3 3 3 3 Maintenance of mitochondrial morphology protein 1 F-actin_cap_A PF01267.17 EGF79220.1 - 1.4e-86 290.2 0.2 1.6e-86 290.0 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit SBDS_C PF09377.10 EGF79220.1 - 0.032 14.3 0.0 0.086 12.9 0.0 1.8 1 1 0 1 1 1 0 SBDS protein C-terminal domain Ribosomal_S4e PF00900.20 EGF79221.1 - 3.2e-37 126.3 1.4 1.4e-36 124.2 1.0 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGF79221.1 - 3.5e-26 90.6 0.1 7e-26 89.6 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGF79221.1 - 1.4e-20 73.1 9.1 2.7e-20 72.2 9.1 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 EGF79221.1 - 6.7e-05 22.7 2.2 6.7e-05 22.7 2.2 2.7 3 0 0 3 3 3 1 KOW motif S4 PF01479.25 EGF79221.1 - 6.7e-05 22.5 2.3 8.3e-05 22.2 0.0 2.3 3 0 0 3 3 3 1 S4 domain Ntox22 PF15527.6 EGF79221.1 - 0.16 12.1 0.1 0.38 10.8 0.1 1.5 1 1 0 1 1 1 0 Bacterial toxin 22 PEX11 PF05648.14 EGF79222.1 - 9.1e-49 165.9 3.8 1e-48 165.8 3.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ETRAMP PF09716.10 EGF79222.1 - 0.0025 17.8 0.3 0.0054 16.8 0.3 1.7 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Kinesin PF00225.23 EGF79223.1 - 2.4e-104 348.8 0.1 2.8e-104 348.7 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF79223.1 - 7e-27 94.2 0.0 1.7e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 EGF79223.1 - 0.039 13.4 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Elong-fact-P_C PF09285.11 EGF79224.1 - 7.8e-14 51.2 0.0 1.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 EGF79224.1 - 3e-12 46.4 0.1 5.3e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 EGF79224.1 - 2.3e-11 43.6 0.1 4.9e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EF_assoc_2 PF08356.12 EGF79225.1 - 3.3e-35 120.0 0.0 1.5e-34 117.8 0.0 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 EGF79225.1 - 4.7e-33 114.1 0.0 3.4e-22 78.8 0.0 2.3 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 EGF79225.1 - 7.4e-31 105.6 0.7 1.4e-30 104.7 0.7 1.5 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 EGF79225.1 - 5e-21 75.1 0.0 4.3e-12 46.3 0.0 2.9 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGF79225.1 - 6e-10 39.2 0.0 0.0002 21.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 EGF79225.1 - 8.2e-08 32.6 0.1 0.00017 22.0 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair AAA_18 PF13238.6 EGF79225.1 - 2.2e-07 31.5 0.0 0.0065 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arf PF00025.21 EGF79225.1 - 4.6e-07 29.5 0.4 0.0016 18.0 0.2 3.0 2 2 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 EGF79225.1 - 1.7e-06 28.5 0.0 0.061 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_6 PF13405.6 EGF79225.1 - 2.3e-06 27.1 1.0 0.00052 19.7 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain AAA_22 PF13401.6 EGF79225.1 - 5.3e-06 26.8 0.1 0.19 12.0 0.0 3.0 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EGF79225.1 - 7.6e-06 26.5 0.0 0.067 13.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_5 PF07728.14 EGF79225.1 - 1.1e-05 25.4 0.0 0.007 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EGF79225.1 - 1.4e-05 25.1 0.5 0.035 14.0 0.1 3.5 2 1 1 3 3 3 1 RsgA GTPase NB-ARC PF00931.22 EGF79225.1 - 1.9e-05 24.0 0.2 0.0093 15.2 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EGF79225.1 - 4.3e-05 23.3 0.0 0.091 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGF79225.1 - 4.4e-05 23.1 0.1 0.083 12.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain EF-hand_10 PF14788.6 EGF79225.1 - 4.6e-05 23.2 2.2 0.00024 20.9 0.2 2.4 2 0 0 2 2 2 1 EF hand AAA_28 PF13521.6 EGF79225.1 - 9.1e-05 22.8 0.0 0.094 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGF79225.1 - 0.00012 21.7 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region G-alpha PF00503.20 EGF79225.1 - 0.00013 21.2 0.1 0.23 10.6 0.0 3.0 3 0 0 3 3 3 1 G-protein alpha subunit RNA_helicase PF00910.22 EGF79225.1 - 0.00015 22.1 0.0 0.51 10.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 EGF79225.1 - 0.00025 21.0 0.1 0.98 9.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Septin PF00735.18 EGF79225.1 - 0.0004 19.8 0.0 0.007 15.7 0.0 2.3 2 0 0 2 2 2 1 Septin Ploopntkinase3 PF18751.1 EGF79225.1 - 0.00048 20.1 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 EF-hand_1 PF00036.32 EGF79225.1 - 0.00068 19.0 2.7 0.0012 18.3 0.3 2.4 2 0 0 2 2 2 1 EF hand SRPRB PF09439.10 EGF79225.1 - 0.0011 18.5 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGF79225.1 - 0.0011 18.7 0.2 0.68 9.7 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGF79225.1 - 0.0032 17.5 0.1 3 7.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EGF79225.1 - 0.0034 17.8 0.0 0.55 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGF79225.1 - 0.0037 17.2 0.1 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EGF79225.1 - 0.0042 17.3 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGF79225.1 - 0.0054 16.8 0.0 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGF79225.1 - 0.0069 16.1 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MCM PF00493.23 EGF79225.1 - 0.0075 15.4 0.0 0.58 9.2 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain TniB PF05621.11 EGF79225.1 - 0.0075 15.7 0.1 1.7 8.0 0.0 2.8 3 0 0 3 3 3 1 Bacterial TniB protein Pox_A32 PF04665.12 EGF79225.1 - 0.013 15.0 0.1 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 EGF79225.1 - 0.013 15.3 1.0 13 5.5 0.1 3.8 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EGF79225.1 - 0.013 15.6 0.2 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 EGF79225.1 - 0.016 15.3 0.5 2.2 8.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_23 PF13476.6 EGF79225.1 - 0.02 15.4 0.5 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGF79225.1 - 0.027 13.6 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EGF79225.1 - 0.034 13.7 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGF79225.1 - 0.039 13.2 0.0 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.16 EGF79225.1 - 0.046 13.0 0.7 0.099 12.0 0.2 1.8 2 0 0 2 2 1 0 AIG1 family ATP-synt_ab PF00006.25 EGF79225.1 - 0.052 13.2 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain VirE PF05272.11 EGF79225.1 - 0.054 13.2 0.0 8.1 6.1 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.9 EGF79225.1 - 0.059 12.5 0.1 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.19 EGF79225.1 - 0.059 13.0 4.1 10 5.7 0.0 3.6 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_8 PF13833.6 EGF79225.1 - 0.062 13.2 0.1 0.84 9.5 0.2 2.8 2 0 0 2 2 2 0 EF-hand domain pair TrwB_AAD_bind PF10412.9 EGF79225.1 - 0.068 12.1 0.1 6.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_CBD PF04963.13 EGF79225.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain SRP54 PF00448.22 EGF79225.1 - 0.072 12.7 0.1 8 6.0 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain MobB PF03205.14 EGF79225.1 - 0.17 11.8 0.3 7.8 6.4 0.1 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 EGF79225.1 - 0.2 11.0 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Usp PF00582.26 EGF79226.1 - 0.00075 20.0 0.1 0.00089 19.8 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4974 PF16344.5 EGF79226.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) LRR_6 PF13516.6 EGF79227.1 - 1.5e-08 34.0 16.8 0.058 13.5 0.1 7.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EGF79227.1 - 0.014 15.8 4.9 15 6.6 0.6 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 EGF79227.1 - 0.081 13.4 8.8 7.2 7.2 0.3 4.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF79227.1 - 2.1 8.2 8.5 0.7 9.7 0.1 4.2 3 2 1 4 4 4 0 Leucine rich repeat ER PF01133.17 EGF79229.1 - 3.4e-31 107.2 0.3 4.9e-31 106.6 0.3 1.2 1 0 0 1 1 1 1 Enhancer of rudimentary DSPc PF00782.20 EGF79230.1 - 1.7e-27 95.8 0.0 3.8e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF79230.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGF79230.1 - 0.0082 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGF79230.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate SMC_N PF02463.19 EGF79231.1 - 8.3e-25 87.5 0.1 4.8e-12 45.8 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGF79231.1 - 2.6e-09 37.3 2.7 2.6e-09 37.3 2.7 3.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EGF79231.1 - 3.6e-07 30.9 45.2 3.6e-07 30.9 45.2 5.8 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGF79231.1 - 2.2e-05 24.4 0.0 0.038 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF79231.1 - 0.00016 21.3 0.0 0.00054 19.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF503 PF04456.12 EGF79231.1 - 0.0063 16.3 0.2 0.046 13.6 0.2 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF503) AAA_27 PF13514.6 EGF79231.1 - 0.0085 15.7 0.0 0.0085 15.7 0.0 3.8 5 1 0 5 5 5 1 AAA domain AAA_25 PF13481.6 EGF79231.1 - 0.016 14.8 0.0 0.065 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGF79231.1 - 0.32 11.4 5.6 1.6 9.1 0.0 3.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF79231.1 - 2.4 8.4 5.7 4.8 7.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain BolA PF01722.18 EGF79232.1 - 1.3e-31 108.7 0.5 1.7e-31 108.3 0.5 1.2 1 0 0 1 1 1 1 BolA-like protein Polysacc_deac_1 PF01522.21 EGF79233.1 - 2.4e-29 101.7 0.0 4.1e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EGF79233.1 - 0.061 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Ribosomal_L33 PF00471.20 EGF79234.1 - 4.6e-10 39.8 0.0 8.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 CH PF00307.31 EGF79235.1 - 5.8e-09 36.1 0.8 1e-05 25.6 0.1 2.4 2 1 0 2 2 2 2 Calponin homology (CH) domain DEAD PF00270.29 EGF79236.1 - 1.3e-48 165.1 0.0 1.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF79236.1 - 1.9e-28 99.0 0.0 4.9e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF79236.1 - 0.0043 17.1 0.0 0.0074 16.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGF79236.1 - 0.083 13.2 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribophorin_I PF04597.14 EGF79237.1 - 4.4e-120 401.9 12.1 6.4e-120 401.3 12.1 1.2 1 0 0 1 1 1 1 Ribophorin I KorB PF08535.10 EGF79237.1 - 0.021 14.9 0.2 0.054 13.5 0.2 1.7 1 0 0 1 1 1 0 KorB domain TMPIT PF07851.13 EGF79237.1 - 0.17 11.1 2.5 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 EGF79237.1 - 0.28 11.4 1.6 0.95 9.8 1.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EMP70 PF02990.16 EGF79238.1 - 5.9e-23 81.3 0.0 7.2e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 EGF79239.1 - 2e-116 389.7 28.5 2.5e-116 389.4 28.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 IMPDH PF00478.25 EGF79240.1 - 8.7e-136 452.5 1.8 1e-135 452.2 1.8 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGF79240.1 - 3e-12 46.8 0.1 4.4e-06 27.0 0.1 2.9 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EGF79240.1 - 1.1e-10 41.5 0.3 6.2e-08 32.4 1.4 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGF79240.1 - 4.1e-09 35.9 2.6 3.7e-08 32.8 1.0 2.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EGF79240.1 - 3.6e-07 29.9 2.4 1.1e-05 25.1 0.3 2.5 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 EGF79240.1 - 0.00046 19.6 0.4 0.0009 18.6 0.4 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGF79240.1 - 0.0083 15.3 2.5 0.37 9.8 0.2 2.3 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 EGF79240.1 - 0.0086 15.3 0.9 0.03 13.5 0.9 1.9 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 EGF79240.1 - 0.0089 15.2 1.1 0.48 9.5 0.0 3.0 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase DHO_dh PF01180.21 EGF79240.1 - 0.011 15.0 7.7 0.043 13.0 0.5 2.7 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EGF79240.1 - 0.012 15.1 2.0 0.62 9.4 0.1 3.1 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator Aldolase PF01081.19 EGF79240.1 - 0.037 13.5 1.0 0.091 12.2 0.2 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase DUF561 PF04481.12 EGF79240.1 - 0.082 12.1 1.3 0.55 9.4 0.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF561) Pkinase PF00069.25 EGF79241.1 - 4e-48 164.1 1.2 2e-45 155.2 1.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79241.1 - 6.3e-20 71.5 0.9 8.4e-14 51.5 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGF79241.1 - 0.0011 18.3 0.2 0.0015 17.9 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGF79241.1 - 0.0042 16.2 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGF79241.1 - 0.0071 15.7 0.0 0.12 11.7 0.0 2.2 1 1 2 3 3 3 1 Kinase-like FTA2 PF13095.6 EGF79241.1 - 0.019 14.6 0.3 3.5 7.2 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGF79241.1 - 0.11 12.3 0.2 0.26 11.2 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family EAP30 PF04157.16 EGF79242.1 - 1.1e-78 263.8 0.1 1.2e-78 263.6 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Arf PF00025.21 EGF79243.1 - 1.2e-77 259.3 0.1 1.4e-77 259.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF79243.1 - 1.2e-15 57.8 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGF79243.1 - 1.6e-14 53.8 0.0 2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGF79243.1 - 6.7e-12 45.2 0.4 1.8e-07 30.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGF79243.1 - 2.4e-11 43.4 0.0 2.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGF79243.1 - 2.6e-10 40.1 0.0 3.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGF79243.1 - 4.9e-06 26.6 0.0 9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF79243.1 - 0.00085 18.9 0.2 0.0063 16.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGF79243.1 - 0.0029 16.6 0.3 0.27 10.2 0.1 2.8 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGF79243.1 - 0.0065 17.0 0.0 0.0089 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF79243.1 - 0.014 15.3 0.1 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ODC_AZ PF02100.17 EGF79243.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme SRP54 PF00448.22 EGF79243.1 - 0.017 14.7 0.2 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 EGF79243.1 - 0.024 14.2 0.2 5.1 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EGF79243.1 - 0.065 13.7 0.3 0.13 12.8 0.3 1.7 1 1 0 1 1 1 0 ABC transporter DUF5486 PF17588.2 EGF79243.1 - 0.14 12.1 0.5 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) TRAP_alpha PF03896.16 EGF79246.1 - 8.3e-06 25.2 0.4 9.7e-06 25.0 0.4 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF3328 PF11807.8 EGF79246.1 - 0.23 11.2 1.1 0.97 9.2 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) DUF2529 PF10740.9 EGF79246.1 - 0.28 10.8 0.9 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) E1-E2_ATPase PF00122.20 EGF79247.1 - 1.6e-23 83.1 0.2 1.6e-23 83.1 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGF79247.1 - 1.2e-12 48.6 0.2 1.5e-06 28.6 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF79247.1 - 7.6e-05 22.3 0.0 0.00022 20.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGF79247.1 - 0.026 14.6 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) S6PP PF05116.13 EGF79247.1 - 0.05 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Mito_carr PF00153.27 EGF79248.1 - 8.5e-53 176.3 3.5 1.3e-18 66.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-RING_2 PF13639.6 EGF79249.1 - 1.6e-09 37.9 9.8 4.3e-09 36.6 6.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGF79249.1 - 3.7e-08 33.5 7.3 5.9e-08 32.9 5.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF79249.1 - 1.3e-05 24.9 9.2 1.7e-05 24.6 6.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF79249.1 - 3.6e-05 23.5 6.6 6.7e-05 22.7 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF79249.1 - 4.1e-05 23.5 7.1 0.0001 22.2 2.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGF79249.1 - 7.3e-05 22.4 3.2 0.0003 20.5 0.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGF79249.1 - 0.00028 20.9 0.9 0.00028 20.9 0.9 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGF79249.1 - 0.00074 19.4 2.9 0.00074 19.4 2.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGF79249.1 - 0.0011 18.5 1.6 0.0011 18.5 1.6 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EGF79249.1 - 0.0012 18.7 6.7 0.0036 17.1 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF79249.1 - 0.0053 16.6 3.6 0.0053 16.6 3.6 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 CheX PF13690.6 EGF79249.1 - 0.017 15.3 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX zinc_ribbon_16 PF17034.5 EGF79249.1 - 0.14 12.4 1.6 0.28 11.4 1.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 EGF79249.1 - 0.22 11.4 2.7 0.5 10.2 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 EGF79249.1 - 0.66 10.1 3.7 1.6 8.9 3.7 1.6 1 0 0 1 1 1 0 Zinc-finger CLASP_N PF12348.8 EGF79250.1 - 0.052 13.1 1.1 0.15 11.6 1.1 1.8 1 0 0 1 1 1 0 CLASP N terminal Peptidase_S10 PF00450.22 EGF79251.1 - 1.5e-110 370.5 0.2 1.8e-110 370.3 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase HA PF03457.14 EGF79251.1 - 0.14 12.5 0.0 0.48 10.8 0.0 1.9 1 0 0 1 1 1 0 Helicase associated domain EF1G PF00647.19 EGF79252.1 - 1.9e-47 159.7 0.1 3.8e-47 158.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGF79252.1 - 1.7e-19 69.9 3.1 3e-19 69.1 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF79252.1 - 3.8e-13 49.5 3.6 6.1e-13 48.8 0.0 3.0 3 1 1 4 4 4 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGF79252.1 - 9.4e-10 38.8 0.0 4.4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGF79252.1 - 1e-09 38.3 0.3 3.4e-08 33.4 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGF79252.1 - 4.7e-07 29.9 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGF79252.1 - 3.4e-06 27.3 0.0 8.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EGF79252.1 - 0.025 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.19 EGF79252.1 - 0.056 14.0 8.4 0.14 12.8 8.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein HABP4_PAI-RBP1 PF04774.15 EGF79252.1 - 0.13 13.1 1.8 0.22 12.4 1.8 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DUF4815 PF16075.5 EGF79252.1 - 0.16 10.2 0.3 0.25 9.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) GST_C_6 PF17171.4 EGF79252.1 - 0.17 11.7 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Roc PF08477.13 EGF79253.1 - 3.1e-06 27.4 0.0 4.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EGF79253.1 - 0.00018 22.0 0.0 0.00023 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 EGF79253.1 - 0.0056 16.3 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Ras family ATPase_2 PF01637.18 EGF79253.1 - 0.0089 16.0 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EGF79253.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGF79253.1 - 0.026 14.9 0.1 0.08 13.3 0.0 1.9 1 1 1 2 2 2 0 RNA helicase DUF3364 PF11844.8 EGF79253.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) AAA_22 PF13401.6 EGF79253.1 - 0.067 13.5 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGF79253.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGF79253.1 - 0.2 12.0 0.0 0.28 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PPR_2 PF13041.6 EGF79254.1 - 2.6e-09 37.1 0.1 0.0012 19.0 0.0 5.7 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.6 EGF79254.1 - 2.9e-08 33.6 1.0 0.006 16.6 0.0 5.4 4 1 2 6 6 6 1 Pentatricopeptide repeat domain PPR PF01535.20 EGF79254.1 - 9.2e-07 28.7 0.2 0.13 12.5 0.0 5.6 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 EGF79254.1 - 0.0001 21.7 0.1 0.0013 18.1 0.0 2.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGF79254.1 - 0.00013 21.6 2.3 0.035 13.8 0.1 3.7 4 0 0 4 4 4 2 PPR repeat MiaE_2 PF13794.6 EGF79254.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like GMP_synt_C PF00958.22 EGF79254.1 - 0.21 11.7 1.3 2.1 8.5 0.0 2.8 2 1 0 3 3 3 0 GMP synthase C terminal domain Alk_phosphatase PF00245.20 EGF79255.1 - 1.5e-59 202.1 0.1 6.5e-59 199.9 0.1 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Alk_phosphatase PF00245.20 EGF79256.1 - 6.4e-59 200.0 0.1 1.1e-57 196.0 0.1 2.2 1 1 0 1 1 1 1 Alkaline phosphatase Acetyltransf_10 PF13673.7 EGF79257.1 - 6.2e-09 35.9 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF79257.1 - 9.5e-09 35.6 0.0 2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF79257.1 - 1.2e-08 35.2 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGF79257.1 - 3.2e-05 23.8 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein PHD PF00628.29 EGF79257.1 - 0.0071 16.2 7.5 0.0071 16.2 7.5 1.8 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 EGF79257.1 - 0.009 16.1 4.0 0.023 14.8 4.0 1.7 1 0 0 1 1 1 1 PHD-finger ArgJ PF01960.18 EGF79257.1 - 0.013 14.3 3.0 0.021 13.6 3.0 1.2 1 0 0 1 1 1 0 ArgJ family Zn_Tnp_IS1595 PF12760.7 EGF79257.1 - 0.44 10.6 2.1 1.2 9.2 2.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_1 PF00130.22 EGF79257.1 - 3.1 7.7 8.2 0.53 10.2 3.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SET PF00856.28 EGF79258.1 - 6.4e-15 55.9 0.3 3.1e-14 53.7 0.3 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGF79258.1 - 2.7e-08 33.8 10.8 2.7e-08 33.8 10.8 2.7 2 0 0 2 2 2 1 MYND finger Epimerase PF01370.21 EGF79259.1 - 8.2e-25 87.7 0.1 1.1e-24 87.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGF79259.1 - 8.2e-15 54.7 0.2 1.2e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGF79259.1 - 2.3e-14 53.5 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGF79259.1 - 3.2e-11 42.8 0.1 5.8e-11 41.9 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGF79259.1 - 1.9e-08 34.4 0.7 4.4e-08 33.2 0.7 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGF79259.1 - 0.00019 20.7 0.2 0.00042 19.5 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGF79259.1 - 0.003 16.8 0.4 0.026 13.7 0.4 2.4 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 EGF79259.1 - 0.0042 17.3 0.1 0.024 14.9 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGF79259.1 - 0.064 13.7 0.1 0.31 11.5 0.1 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain zf-C2H2_4 PF13894.6 EGF79260.1 - 4.5e-09 36.4 19.5 0.00021 21.9 0.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF79260.1 - 7.7e-09 35.5 22.3 0.00016 21.9 0.2 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EGF79260.1 - 0.0006 19.5 7.8 0.003 17.3 0.1 2.8 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGF79260.1 - 0.00099 19.3 5.7 0.058 13.7 2.6 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGF79260.1 - 0.048 14.1 1.0 0.048 14.1 1.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 EGF79260.1 - 0.058 13.8 16.3 0.2 12.1 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGF79260.1 - 0.1 12.6 0.3 0.1 12.6 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGF79260.1 - 0.14 12.4 3.4 0.61 10.4 3.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 EGF79260.1 - 0.53 10.4 7.8 3.9 7.7 0.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 EGF79260.1 - 1 9.9 10.8 12 6.5 10.8 2.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Pkinase PF00069.25 EGF79261.1 - 3.8e-72 242.8 0.0 4.6e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79261.1 - 2.2e-43 148.4 0.0 3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF79261.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF79261.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF79261.1 - 0.0037 16.3 0.1 0.005 15.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGF79261.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EGF79261.1 - 0.25 10.1 2.2 0.51 9.1 2.2 1.6 1 1 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 EGF79263.1 - 1.1e-15 57.8 10.5 9.8e-05 23.1 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79263.1 - 8.3e-09 35.6 0.0 2.3 8.6 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF79263.1 - 0.00095 19.1 0.3 0.0071 16.2 0.1 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGF79263.1 - 0.0045 16.4 0.1 6.1 6.1 0.1 3.6 3 1 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 EGF79263.1 - 0.012 14.3 0.1 0.027 13.1 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Lipase_3 PF01764.25 EGF79264.1 - 5.5e-18 65.2 0.0 9.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGF79264.1 - 0.041 13.1 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF996 PF06195.13 EGF79264.1 - 0.064 13.5 5.4 0.059 13.7 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF2974 PF11187.8 EGF79264.1 - 0.1 12.2 0.1 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) NIF PF03031.18 EGF79265.1 - 9.2e-29 100.2 0.1 1.8e-28 99.3 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DNA_pol_phi PF04931.13 EGF79265.1 - 0.027 12.6 3.8 0.063 11.4 4.1 1.4 1 1 1 2 2 2 0 DNA polymerase phi DUF3110 PF11360.8 EGF79265.1 - 0.11 12.8 0.4 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) YbgS PF13985.6 EGF79266.1 - 0.013 15.7 0.6 0.021 15.1 0.1 1.6 2 0 0 2 2 2 0 YbgS-like protein zf-RING_2 PF13639.6 EGF79269.1 - 5.2e-13 49.1 6.1 7.7e-13 48.6 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGF79269.1 - 5.1e-09 35.7 1.5 5.1e-09 35.7 1.5 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGF79269.1 - 8.3e-09 35.6 4.1 1.6e-08 34.7 4.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF79269.1 - 1.3e-07 31.4 4.6 1.9e-07 30.8 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF79269.1 - 1.3e-07 31.4 4.9 2e-07 30.8 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF79269.1 - 1.5e-07 31.3 3.8 2.1e-07 30.8 3.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGF79269.1 - 2e-05 24.3 3.2 3.5e-05 23.6 3.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGF79269.1 - 3.6e-05 23.5 3.7 5.7e-05 22.9 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF79269.1 - 0.00025 21.0 1.4 0.00049 20.1 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGF79269.1 - 0.00035 20.5 3.1 0.00049 20.1 0.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 EGF79269.1 - 0.0026 17.9 4.6 0.033 14.4 3.2 2.3 1 1 1 2 2 2 1 FANCL C-terminal domain RINGv PF12906.7 EGF79269.1 - 0.019 15.1 4.5 0.036 14.2 4.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EGF79269.1 - 0.067 13.0 4.2 0.13 12.0 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGF79269.1 - 0.1 12.2 3.6 0.18 11.4 3.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EGF79269.1 - 0.75 9.7 3.2 1.5 8.8 3.2 1.5 1 1 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 EGF79269.1 - 0.95 9.6 3.2 1.8 8.7 3.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Asparaginase PF00710.20 EGF79270.1 - 4.4e-59 199.2 0.0 7.5e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.7 EGF79270.1 - 5e-19 68.7 0.6 1.6e-09 38.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 EGF79270.1 - 1.6e-18 67.0 0.0 3.5e-17 62.7 0.0 2.7 1 1 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 EGF79270.1 - 6.3e-15 55.3 1.2 2e-06 28.2 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF79270.1 - 1.3e-14 54.1 2.9 5.9e-07 29.6 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGF79270.1 - 2.6e-12 46.6 5.6 1.1e-05 25.7 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EGF79270.1 - 9.1e-12 44.1 2.0 0.00054 20.2 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Y_phosphatase2 PF03162.13 EGF79271.1 - 2.1e-36 125.0 0.0 2.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGF79271.1 - 0.00059 19.9 0.0 0.0015 18.5 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGF79271.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Npa1 PF11707.8 EGF79272.1 - 2.9e-83 280.0 4.8 1.3e-82 277.9 0.2 2.8 2 1 0 2 2 2 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EGF79272.1 - 1.1e-48 165.4 1.6 6.1e-48 163.1 1.6 2.5 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 CrgA PF06781.12 EGF79274.1 - 0.0082 16.2 0.1 0.0082 16.2 0.1 2.5 3 2 2 5 5 5 1 Cell division protein CrgA Pil1 PF13805.6 EGF79276.1 - 1.6e-23 83.6 0.3 2e-23 83.3 0.3 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 Med30 PF11315.8 EGF79276.1 - 0.0041 17.3 0.4 0.0073 16.5 0.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 30 MCM_N PF14551.6 EGF79276.1 - 0.0052 17.3 0.0 0.0085 16.7 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Sec34 PF04136.15 EGF79276.1 - 0.046 13.6 0.5 0.091 12.6 0.5 1.5 1 0 0 1 1 1 0 Sec34-like family FTA4 PF13093.6 EGF79276.1 - 0.063 13.2 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Zn_clus PF00172.18 EGF79277.1 - 5.7e-05 23.2 10.6 5.7e-05 23.2 10.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.12 EGF79278.1 - 4.4e-29 100.6 0.1 8.7e-29 99.7 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EGF79278.1 - 1.3e-21 76.6 3.2 1.3e-21 76.6 3.2 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGF79278.1 - 1.1e-07 32.0 10.6 1.1e-07 32.0 10.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF79278.1 - 6.7e-06 25.8 10.7 2.3e-05 24.2 10.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF79278.1 - 0.00014 21.7 9.3 0.00044 20.1 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF79278.1 - 0.00014 21.8 4.1 0.00014 21.8 4.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGF79278.1 - 0.00034 20.8 7.4 0.00034 20.8 7.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGF79278.1 - 0.0013 18.4 7.5 0.0013 18.4 7.5 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGF79278.1 - 0.0056 16.6 7.9 0.0056 16.6 7.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGF79278.1 - 0.0079 16.2 5.5 0.0079 16.2 5.5 2.0 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGF79278.1 - 0.0096 15.8 6.8 0.0096 15.8 6.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 EGF79278.1 - 0.094 12.8 8.3 0.15 12.1 8.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Thioredoxin_4 PF13462.6 EGF79278.1 - 0.2 11.8 2.9 15 5.7 0.2 2.6 2 0 0 2 2 2 0 Thioredoxin zf-RING_4 PF14570.6 EGF79278.1 - 0.29 11.0 5.6 0.82 9.5 5.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGF79278.1 - 2 8.6 9.8 3.3 8.0 7.6 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SLD3 PF08639.10 EGF79280.1 - 4.7e-12 45.4 11.6 1.3e-11 44.0 11.6 1.4 1 1 0 1 1 1 1 DNA replication regulator SLD3 PhoLip_ATPase_C PF16212.5 EGF79282.1 - 8.3e-77 258.3 24.4 8.3e-77 258.3 24.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGF79282.1 - 5.6e-25 86.8 2.6 2.6e-24 84.7 0.3 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGF79282.1 - 3e-12 47.3 0.8 6.8e-07 29.8 0.2 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGF79282.1 - 1.5e-10 41.0 0.0 6.2e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGF79282.1 - 3.9e-06 26.5 0.1 2.5e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGF79282.1 - 0.00011 22.0 0.3 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjcZ_2 PF09680.10 EGF79282.1 - 0.65 9.7 5.5 1.7 8.4 5.5 1.7 1 0 0 1 1 1 0 Family of unknown function PfkB PF00294.24 EGF79283.1 - 6.6e-38 130.7 0.1 9.3e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Big_6 PF17936.1 EGF79283.1 - 0.046 14.0 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig domain FixH PF05751.11 EGF79283.1 - 0.18 11.8 0.1 0.7 9.9 0.1 1.8 1 1 0 1 1 1 0 FixH GHMP_kinases_C PF08544.13 EGF79283.1 - 0.25 11.7 1.1 0.5 10.8 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal Mito_carr PF00153.27 EGF79284.1 - 2.1e-59 197.5 2.9 2.6e-19 68.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CRAL_TRIO PF00650.20 EGF79285.1 - 4.3e-35 120.8 0.0 1.7e-33 115.6 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGF79285.1 - 4.6e-09 36.5 0.0 6.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGF79285.1 - 8.4e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Pkinase PF00069.25 EGF79286.1 - 3.8e-72 242.8 0.0 4.6e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79286.1 - 2.2e-43 148.4 0.0 3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF79286.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF79286.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF79286.1 - 0.0037 16.3 0.1 0.005 15.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGF79286.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EGF79286.1 - 0.25 10.1 2.2 0.51 9.1 2.2 1.6 1 1 0 1 1 1 0 Fungal protein kinase Ribosomal_L29 PF00831.23 EGF79287.1 - 3.8e-19 68.4 0.9 3.8e-19 68.4 0.9 2.2 2 1 1 3 3 3 1 Ribosomal L29 protein MRP-L47 PF06984.13 EGF79287.1 - 0.081 13.0 0.2 0.21 11.7 0.2 1.7 1 1 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Sirohm_synth_M PF14824.6 EGF79287.1 - 0.7 9.4 2.8 2.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Macoilin PF09726.9 EGF79288.1 - 4.7 5.6 13.6 5.1 5.5 13.6 1.0 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 EGF79289.1 - 5.5e-51 173.5 0.1 7.3e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79289.1 - 4.1e-24 85.3 0.0 7.5e-24 84.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF79289.1 - 0.00023 20.1 0.4 0.00033 19.6 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGF79289.1 - 0.00048 19.2 0.1 0.00072 18.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGF79289.1 - 0.024 14.2 0.2 0.21 11.2 0.1 1.9 1 1 1 2 2 2 0 RIO1 family Trp_syntA PF00290.20 EGF79290.1 - 9e-93 309.9 0.1 1.4e-92 309.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EGF79290.1 - 8.6e-48 163.2 0.4 1.4e-47 162.6 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 EGF79290.1 - 0.089 12.2 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein TFIIS_C PF01096.18 EGF79291.1 - 5.5e-16 58.1 0.9 5.5e-16 58.1 0.9 2.6 3 0 0 3 3 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGF79291.1 - 0.00021 21.1 12.6 0.0026 17.6 2.0 3.1 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 EGF79291.1 - 0.0011 19.0 9.0 0.024 14.6 1.0 2.9 2 1 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EGF79291.1 - 0.085 12.3 7.0 7.2 6.2 0.5 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 EGF79291.1 - 0.12 12.2 4.5 7.5 6.5 0.4 3.4 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Lar_restr_allev PF14354.6 EGF79291.1 - 0.16 12.4 11.5 0.52 10.7 0.7 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar eIF-5_eIF-2B PF01873.17 EGF79291.1 - 0.18 11.7 7.4 1.2 9.0 0.4 3.0 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Zn_ribbon_recom PF13408.6 EGF79291.1 - 0.27 11.8 4.7 3.3 8.3 0.1 3.1 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.19 EGF79291.1 - 0.69 9.7 6.1 1.3 8.9 2.2 2.8 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Jas PF16135.5 EGF79291.1 - 0.78 10.0 4.7 0.42 10.8 1.6 2.0 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling TF_Zn_Ribbon PF08271.12 EGF79291.1 - 3.2 7.3 17.1 2.9 7.5 2.3 3.3 2 2 0 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EGF79291.1 - 6.8 6.9 11.7 0.24 11.6 0.9 2.8 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.6 EGF79291.1 - 8.3 6.3 12.6 4.9 7.0 0.1 3.7 4 0 0 4 4 3 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 EGF79291.1 - 9.5 6.0 16.8 4 7.2 3.1 3.6 2 2 1 3 3 3 0 Ribosomal protein S27 DUF4200 PF13863.6 EGF79292.1 - 2.2e-33 115.2 23.1 2.2e-33 115.2 23.1 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4200) RNase_J_C PF17770.1 EGF79292.1 - 5 8.3 0.0 5 8.3 0.0 4.2 4 0 0 4 4 4 0 Ribonuclease J C-terminal domain ORC6 PF05460.13 EGF79293.1 - 0.19 11.0 2.8 4.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ephrin_rec_like PF07699.13 EGF79294.1 - 0.0066 16.2 5.3 0.0066 16.2 5.3 2.1 1 1 1 2 2 2 1 Putative ephrin-receptor like EGF_CA PF07645.15 EGF79294.1 - 9.2 6.6 10.0 5 7.4 2.7 2.5 1 1 0 2 2 2 0 Calcium-binding EGF domain Meckelin PF09773.9 EGF79295.1 - 7e-140 467.7 10.2 2.6e-138 462.5 10.2 2.0 1 1 0 1 1 1 1 Meckelin (Transmembrane protein 67) CDC27 PF09507.10 EGF79296.1 - 1.5e-30 107.0 30.4 1.9e-30 106.7 30.4 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Oxidored_q6 PF01058.22 EGF79297.1 - 1.5e-23 83.1 0.1 1.9e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Peptidase_S8 PF00082.22 EGF79298.1 - 2.6e-35 122.1 11.8 6e-35 120.9 11.8 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGF79298.1 - 0.016 15.9 0.1 0.041 14.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase inhibitor I9 DUF3818 PF12825.7 EGF79299.1 - 3.7e-10 39.3 1.0 2.1e-05 23.7 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) DUF747 PF05346.11 EGF79300.1 - 1.4e-114 382.9 11.9 1.8e-114 382.5 11.9 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Rhodanese PF00581.20 EGF79301.1 - 5.2e-25 88.0 0.0 1.1e-13 51.6 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 EGF79301.1 - 0.0079 16.0 0.0 0.17 11.7 0.0 2.7 2 1 0 2 2 2 1 ThiC-associated domain BPL_LplA_LipB PF03099.19 EGF79304.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family AKAP28 PF14469.6 EGF79305.1 - 2.1e-05 24.3 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 28 kDa A-kinase anchor Botulinum_HA-17 PF05588.11 EGF79305.1 - 0.0071 16.5 0.3 5.3 7.1 0.2 2.7 2 0 0 2 2 2 2 Clostridium botulinum HA-17 domain mRNA_cap_enzyme PF01331.19 EGF79306.1 - 1.8e-30 106.3 0.2 3.5e-20 72.7 0.1 2.2 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGF79306.1 - 7.6e-14 52.3 0.8 1.2e-12 48.4 0.8 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EGF79306.1 - 6.5e-07 29.2 0.1 2.2e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Cu-oxidase PF00394.22 EGF79307.1 - 4.7e-46 156.8 1.4 2.3e-44 151.3 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGF79307.1 - 6.4e-34 116.5 6.3 8e-30 103.3 0.1 4.3 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGF79307.1 - 8.7e-33 113.0 7.1 3.4e-15 56.0 0.9 4.5 5 0 0 5 5 5 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EGF79307.1 - 0.037 14.1 0.0 3.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Cupredoxin-like domain ARD PF03079.14 EGF79308.1 - 1.4e-51 174.7 1.1 2.3e-51 174.1 1.1 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGF79308.1 - 2.1e-09 37.0 0.0 4.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGF79308.1 - 3.2e-07 30.3 0.0 5.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGF79308.1 - 0.0082 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Cupin JmjC PF02373.22 EGF79308.1 - 0.088 13.2 0.0 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase CUE PF02845.16 EGF79309.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 EGF79309.1 - 0.00024 21.1 0.2 0.00058 19.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 VWA_2 PF13519.6 EGF79310.1 - 0.012 16.2 0.5 0.046 14.4 0.0 2.2 3 0 0 3 3 3 0 von Willebrand factor type A domain Cyclin PF08613.11 EGF79311.1 - 0.01 16.2 0.4 0.047 14.1 0.0 2.2 2 0 0 2 2 2 0 Cyclin Dynactin_p62 PF05502.13 EGF79312.1 - 5e-54 183.9 19.9 1.3e-33 116.5 14.3 2.2 2 0 0 2 2 2 2 Dynactin p62 family RibD_C PF01872.17 EGF79312.1 - 4.7e-05 23.3 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain DUF3429 PF11911.8 EGF79313.1 - 8e-30 104.0 12.3 1e-29 103.6 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Zn_ribbon_17 PF17120.5 EGF79314.1 - 4.5e-08 32.6 15.8 4.5e-08 32.6 15.8 2.7 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EGF79314.1 - 1.6e-07 31.9 17.0 0.019 15.9 0.0 6.1 5 0 0 5 5 5 3 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 EGF79314.1 - 0.00075 19.7 13.0 0.0022 18.2 13.0 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family RNA_pol_Rpb1_1 PF04997.12 EGF79314.1 - 0.45 9.8 2.3 0.88 8.8 2.3 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Glyco_transf_22 PF03901.17 EGF79315.1 - 7.2e-36 124.3 19.7 1.1e-35 123.7 19.7 1.3 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family RNA_pol PF00940.19 EGF79316.1 - 1.1e-171 571.3 1.6 1.8e-171 570.6 1.6 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGF79316.1 - 8.1e-61 206.3 0.1 1.6e-60 205.3 0.1 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR PF01535.20 EGF79316.1 - 0.12 12.6 0.0 0.77 10.1 0.0 2.5 1 0 0 1 1 1 0 PPR repeat NAD_kinase PF01513.21 EGF79320.1 - 7.5e-63 212.4 0.0 1.3e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 ATP-NAD kinase DUF1754 PF08555.10 EGF79322.1 - 7.3e-09 36.3 19.1 1.1e-08 35.7 16.0 2.3 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) AC_N PF16214.5 EGF79322.1 - 0.2 10.8 1.2 0.21 10.7 1.2 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CCDC106 PF15794.5 EGF79322.1 - 0.62 9.7 9.4 0.74 9.5 9.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 IFRD PF05004.13 EGF79322.1 - 0.89 8.6 12.7 0.015 14.4 4.9 1.7 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) SSP160 PF06933.11 EGF79322.1 - 3.9 5.6 7.2 4.9 5.2 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Apt1 PF10351.9 EGF79323.1 - 1.5e-107 360.4 6.3 3.4e-107 359.3 6.3 1.6 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 EGF79323.1 - 5.9e-32 110.9 0.0 1.5e-31 109.6 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_WPPW PF10359.9 EGF79323.1 - 3.1e-28 98.9 1.3 3.1e-28 98.9 1.3 2.2 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EGF79323.1 - 1.6e-20 73.6 0.0 5.4e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) GTP_EFTU PF00009.27 EGF79325.1 - 4.3e-22 78.6 0.0 7.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGF79325.1 - 4.8e-07 30.1 0.2 2.7e-06 27.7 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGF79325.1 - 0.00028 21.2 0.2 0.0014 18.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGF79325.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGF79325.1 - 0.0053 16.5 0.1 26 4.5 0.0 3.8 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGF79325.1 - 0.015 15.2 0.1 4 7.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase TFIIB PF00382.19 EGF79326.1 - 0.0049 16.9 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGF79326.1 - 0.82 9.2 4.9 2 8.0 4.9 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding MT-A70 PF05063.14 EGF79327.1 - 2e-40 138.5 0.2 2.3e-40 138.3 0.2 1.0 1 0 0 1 1 1 1 MT-A70 DUF2931 PF11153.8 EGF79327.1 - 0.067 12.9 0.0 0.093 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2931) MINDY_DUB PF04424.13 EGF79328.1 - 5.2e-32 110.3 0.1 1.9e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 MINDY deubiquitinase ECH_1 PF00378.20 EGF79329.1 - 5.8e-16 58.6 0.0 7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF79329.1 - 0.0012 18.4 0.1 0.0014 18.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RTT107_BRCT_5 PF16770.5 EGF79330.1 - 2e-15 56.5 0.0 2e-14 53.3 0.0 2.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EGF79330.1 - 5.1e-06 26.8 0.1 0.00051 20.4 0.0 2.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 EGF79330.1 - 0.043 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 FHA domain Peptidase_M16_M PF16187.5 EGF79331.1 - 6.4e-91 304.5 3.0 1.2e-90 303.7 3.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGF79331.1 - 3.1e-43 147.3 0.0 2.5e-42 144.4 0.1 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGF79331.1 - 1.4e-30 106.7 0.1 4e-21 75.8 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain IZUMO PF15005.6 EGF79331.1 - 0.24 11.9 0.5 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated BSP PF04450.12 EGF79332.1 - 2.3e-62 210.5 0.1 1.1e-36 126.6 0.0 2.5 2 1 0 2 2 2 2 Peptidase of plants and bacteria TPR_1 PF00515.28 EGF79333.1 - 0.00059 19.6 0.4 0.45 10.4 0.0 3.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF79333.1 - 0.0039 17.2 0.2 3.5 8.0 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PH PF00169.29 EGF79333.1 - 0.0099 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 PH domain TPR_16 PF13432.6 EGF79333.1 - 0.12 13.0 0.3 0.72 10.5 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF79333.1 - 0.6 10.4 5.9 12 6.2 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 EGF79334.1 - 1e-13 51.5 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF79334.1 - 2.2e-05 24.8 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGF79334.1 - 0.00026 20.9 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGF79334.1 - 0.066 13.9 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF79334.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein SH3_9 PF14604.6 EGF79336.1 - 0.0014 18.4 0.3 0.004 17.0 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain Npun_R1517 PF18068.1 EGF79336.1 - 0.11 12.9 0.1 1.6 9.2 0.1 2.2 2 0 0 2 2 2 0 Npun R1517 UPF0086 PF01868.16 EGF79337.1 - 4.4e-30 103.4 0.0 1.1e-29 102.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function UPF0086 DUF5511 PF17630.2 EGF79338.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5511) cNMP_binding PF00027.29 EGF79339.1 - 1.6e-21 76.1 0.1 2.3e-15 56.4 0.0 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain CDP-OH_P_transf PF01066.21 EGF79340.1 - 2.5e-13 50.6 0.3 2.5e-13 50.6 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3565 PF12088.8 EGF79340.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) HOK_GEF PF01848.16 EGF79340.1 - 0.098 12.1 1.0 0.23 10.9 1.0 1.6 1 0 0 1 1 1 0 Hok/gef family DPBB_1 PF03330.18 EGF79341.1 - 7.2e-10 39.0 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 EGF79341.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Cerato-platanin Merozoite_SPAM PF07133.11 EGF79341.1 - 0.4 10.7 10.6 0.53 10.3 10.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Cation_ATPase_C PF00689.21 EGF79342.1 - 1.5e-45 155.1 4.9 1.5e-45 155.1 4.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGF79342.1 - 1.5e-34 119.1 4.8 1.5e-34 119.1 4.8 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGF79342.1 - 3.7e-19 69.8 1.4 5.7e-18 66.0 1.4 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGF79342.1 - 2.1e-14 53.3 0.0 4.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGF79342.1 - 3.7e-11 42.5 0.0 8.2e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF79342.1 - 0.0015 18.3 1.3 0.0035 17.1 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Arginase PF00491.21 EGF79343.1 - 2.1e-74 250.5 0.0 2.5e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family OmpA_membrane PF01389.17 EGF79343.1 - 0.049 13.4 0.1 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 OmpA-like transmembrane domain Syntaxin-6_N PF09177.11 EGF79344.1 - 0.00041 20.9 0.5 0.01 16.4 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Med21 PF11221.8 EGF79344.1 - 0.019 15.2 8.0 0.3 11.3 0.6 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Mst1_SARAH PF11629.8 EGF79344.1 - 0.03 14.4 1.7 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Exonuc_VII_L PF02601.15 EGF79344.1 - 0.098 12.2 0.3 0.1 12.1 0.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EGF79344.1 - 0.13 12.3 3.5 0.15 12.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4709 PF15821.5 EGF79344.1 - 0.26 11.6 5.9 1.5 9.1 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) TMPIT PF07851.13 EGF79344.1 - 3.4 6.8 9.1 4.3 6.5 2.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein YtxH PF12732.7 EGF79344.1 - 4.7 7.8 5.9 67 4.1 6.0 2.3 1 1 0 1 1 1 0 YtxH-like protein LZ3wCH PF18517.1 EGF79344.1 - 6.3 7.0 7.9 2.2 8.4 2.2 2.4 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Cnn_1N PF07989.11 EGF79344.1 - 9.4 6.5 11.7 2.6 8.3 1.9 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Ribosomal_L2_C PF03947.18 EGF79345.1 - 1.6e-44 151.2 1.3 3.6e-44 150.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGF79345.1 - 1.2e-21 76.4 0.0 1.2e-21 76.4 0.0 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DUF952 PF06108.12 EGF79346.1 - 4.6e-16 58.6 0.0 6.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) LMBR1 PF04791.16 EGF79347.1 - 0.0044 16.0 0.3 0.005 15.8 0.3 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Fzo_mitofusin PF04799.13 EGF79347.1 - 0.12 11.9 2.4 0.38 10.3 2.4 1.9 1 0 0 1 1 1 0 fzo-like conserved region Peptidase_S46 PF10459.9 EGF79347.1 - 0.25 10.0 3.9 0.34 9.5 3.9 1.1 1 0 0 1 1 1 0 Peptidase S46 PEN-2 PF10251.9 EGF79348.1 - 9.7e-31 106.1 1.9 1.1e-30 105.9 1.9 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase PBS_linker_poly PF00427.21 EGF79349.1 - 0.0026 17.8 0.5 4.5 7.3 0.0 3.0 3 0 0 3 3 3 2 Phycobilisome Linker polypeptide DUF2591 PF10765.9 EGF79349.1 - 0.15 12.3 0.3 40 4.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) Acetyltransf_6 PF13480.7 EGF79349.1 - 7.7 6.7 11.1 27 4.9 0.0 4.1 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain Asp PF00026.23 EGF79350.1 - 1.6e-12 47.5 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79350.1 - 3.8e-05 23.5 0.1 0.00019 21.2 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4246 PF14033.6 EGF79352.1 - 3.5e-30 105.5 0.1 4.6e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Hormone_6 PF00236.18 EGF79353.1 - 0.051 13.6 0.8 0.14 12.1 0.8 1.7 1 0 0 1 1 1 0 Glycoprotein hormone Arm_vescicular PF18770.1 EGF79354.1 - 0.43 10.5 3.6 0.56 10.2 0.5 2.1 1 1 1 2 2 2 0 Armadillo tether-repeat of vescicular transport factor SSTK-IP PF15836.5 EGF79356.1 - 0.22 11.6 6.2 0.47 10.6 0.3 2.2 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein RHSP PF07999.11 EGF79360.1 - 0.053 12.3 0.1 5.9 5.6 0.1 2.2 2 0 0 2 2 2 0 Retrotransposon hot spot protein AAA_29 PF13555.6 EGF79360.1 - 0.056 13.2 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 EGF79360.1 - 0.12 12.5 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Asp PF00026.23 EGF79363.1 - 3e-16 59.7 2.1 8e-15 55.1 2.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79363.1 - 4.5e-05 23.3 0.0 0.00023 21.0 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 EGF79364.1 - 2.2e-11 43.7 0.0 5e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Flagellin_IN PF07196.13 EGF79365.1 - 0.052 13.7 0.1 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 Flagellin hook IN motif AAA_22 PF13401.6 EGF79367.1 - 0.0033 17.7 0.0 0.03 14.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF3484 PF11983.8 EGF79368.1 - 0.074 14.2 0.0 0.17 13.0 0.0 1.6 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch DUF4246 PF14033.6 EGF79369.1 - 1.4e-82 278.2 0.2 1.6e-82 278.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Asp PF00026.23 EGF79370.1 - 5.2e-11 42.5 0.0 1.2e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79370.1 - 8.3e-05 22.4 0.0 0.00042 20.1 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF79370.1 - 0.066 13.9 0.4 3 8.6 0.1 3.0 3 0 0 3 3 3 0 Aspartyl protease ABC_tran PF00005.27 EGF79372.1 - 2.3e-28 99.4 0.0 6.5e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF79372.1 - 6.2e-14 52.5 0.6 2.8e-10 40.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF79372.1 - 0.00012 22.6 0.5 0.0012 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGF79372.1 - 0.00032 20.5 0.1 0.14 11.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 EGF79372.1 - 0.00082 18.9 0.7 0.14 11.6 0.1 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGF79372.1 - 0.0028 17.6 0.1 0.0061 16.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF79372.1 - 0.0037 17.0 0.1 0.0078 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DCX PF03607.17 EGF79372.1 - 0.0079 16.3 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 Doublecortin AAA_16 PF13191.6 EGF79372.1 - 0.0085 16.5 0.0 0.13 12.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RRM_Rrp7 PF17799.1 EGF79372.1 - 0.021 14.6 0.6 0.28 11.0 0.2 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain AAA_13 PF13166.6 EGF79372.1 - 0.05 12.3 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 EGF79372.1 - 0.075 11.9 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 EGF79372.1 - 0.13 12.3 0.1 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RHSP PF07999.11 EGF79374.1 - 0.15 10.9 0.7 1.9 7.2 0.7 2.1 1 1 0 1 1 1 0 Retrotransposon hot spot protein USP7_ICP0_bdg PF12436.8 EGF79375.1 - 0.061 12.6 0.2 0.09 12.1 0.2 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 YbgS PF13985.6 EGF79376.1 - 0.075 13.3 3.2 0.27 11.5 3.2 1.9 1 0 0 1 1 1 0 YbgS-like protein RecG_N PF17190.4 EGF79376.1 - 0.12 13.2 1.2 0.41 11.4 0.4 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain FYRC PF05965.14 EGF79376.1 - 0.25 11.5 2.0 5.2 7.3 0.1 3.3 3 1 0 3 3 3 0 F/Y rich C-terminus Dynactin_p22 PF07426.11 EGF79378.1 - 0.01 15.7 1.0 4.1 7.2 0.0 2.6 1 1 1 2 2 2 0 Dynactin subunit p22 Osmo_CC PF08946.10 EGF79378.1 - 0.075 13.3 1.7 0.41 10.9 0.2 2.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil FAD_SOX PF18371.1 EGF79378.1 - 0.2 12.1 1.0 0.45 10.9 1.0 1.6 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase TetR_C_23 PF17931.1 EGF79378.1 - 1.1 9.4 4.5 0.93 9.6 2.4 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Asp PF00026.23 EGF79379.1 - 4.9e-11 42.6 0.1 9e-11 41.7 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79379.1 - 1.8e-05 24.6 0.1 4.4e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF742 PF05331.11 EGF79379.1 - 0.00048 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF742) PTRF_SDPR PF15237.6 EGF79380.1 - 0.016 14.9 0.1 0.048 13.3 0.1 1.8 1 0 0 1 1 1 0 PTRF/SDPR family zf-C2H2_8 PF15909.5 EGF79380.1 - 0.14 12.5 0.5 16 5.8 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc ribbon Mannosyl_trans3 PF11051.8 EGF79381.1 - 1.8e-45 155.5 0.0 4.4e-45 154.2 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative LEA_2 PF03168.13 EGF79383.1 - 0.021 15.3 0.0 0.19 12.3 0.0 2.2 1 1 0 1 1 1 0 Late embryogenesis abundant protein Herpes_pp85 PF04637.12 EGF79384.1 - 0.61 8.4 2.8 0.68 8.3 2.8 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DnaJ-X PF14308.6 EGF79385.1 - 5.6e-36 124.0 0.0 2.1e-35 122.1 0.0 1.9 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF79385.1 - 1.8e-23 82.4 0.9 3.9e-23 81.4 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EGF79386.1 - 2.5e-12 46.8 0.0 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF79386.1 - 4.7e-05 23.4 0.0 8.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF79386.1 - 0.0025 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF79386.1 - 0.0048 16.3 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF79386.1 - 0.0049 16.5 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EGF79386.1 - 0.0071 16.0 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_Tyr PF07714.17 EGF79386.1 - 0.0085 15.4 0.1 0.027 13.7 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF79386.1 - 0.0098 14.7 0.7 0.016 14.0 0.7 1.5 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGF79386.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF79386.1 - 0.075 13.0 0.4 0.71 9.8 0.1 2.3 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins MIT_C PF16565.5 EGF79387.1 - 0.0031 17.5 0.1 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Phospholipase D-like domain at C-terminus of MIT Serinc PF03348.15 EGF79388.1 - 1.2e-143 479.1 15.0 1.4e-143 479.0 15.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF4231 PF14015.6 EGF79388.1 - 0.66 10.5 16.2 0.5 10.8 0.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Sde2_N_Ubi PF13019.6 EGF79389.1 - 4.8e-35 120.8 0.0 7.3e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Peptidase_M14 PF00246.24 EGF79390.1 - 1.6e-85 287.4 0.0 2e-85 287.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGF79390.1 - 8.9e-12 45.2 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide FYVE PF01363.21 EGF79391.1 - 1.3e-24 86.1 18.9 2.1e-18 66.2 3.3 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EGF79391.1 - 1.3e-10 40.8 0.7 3.4e-10 39.5 0.7 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain GAGA PF09237.11 EGF79391.1 - 0.00092 19.0 0.1 0.0031 17.3 0.1 1.9 1 0 0 1 1 1 1 GAGA factor zf-Di19 PF05605.12 EGF79391.1 - 0.009 16.3 0.3 0.009 16.3 0.3 2.6 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding FYVE_2 PF02318.16 EGF79391.1 - 0.011 16.0 2.9 0.011 16.0 2.9 3.0 3 0 0 3 3 2 0 FYVE-type zinc finger zf-ribbon_3 PF13248.6 EGF79391.1 - 0.075 12.5 8.8 14 5.3 0.1 4.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.26 EGF79391.1 - 0.11 13.0 0.1 0.11 13.0 0.1 4.6 5 0 0 5 5 3 0 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 EGF79391.1 - 0.42 10.2 0.1 0.42 10.2 0.1 2.5 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-RING_7 PF02591.15 EGF79391.1 - 0.75 10.0 0.1 0.75 10.0 0.1 4.2 4 1 0 4 4 4 0 C4-type zinc ribbon domain zinc_ribbon_9 PF14369.6 EGF79391.1 - 1 9.7 6.4 13 6.2 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 EGF79391.1 - 2 8.4 8.7 0.81 9.7 0.7 3.3 4 0 0 4 4 4 0 Putative transposase DNA-binding domain IBR PF01485.21 EGF79391.1 - 3.2 8.0 15.0 4.1 7.7 1.2 3.9 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain Siva PF05458.12 EGF79391.1 - 5 6.8 16.7 1.2 8.8 2.2 3.0 3 0 0 3 3 3 0 Cd27 binding protein (Siva) Synaptobrevin PF00957.21 EGF79392.1 - 1.5e-10 40.7 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Fungal_trans PF04082.18 EGF79393.1 - 5.7e-12 45.2 0.1 1.2e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF79393.1 - 2.6e-07 30.6 9.8 4.9e-07 29.8 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 EGF79394.1 - 1.8e-21 77.0 0.3 7.2e-20 71.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF79394.1 - 4.7e-15 56.8 0.0 6.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF79394.1 - 3.3e-14 52.7 0.0 3.4e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGF79394.1 - 0.00027 20.8 0.0 1.2 8.9 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGF79394.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EGF79394.1 - 0.013 15.2 0.0 0.075 12.7 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 EGF79394.1 - 0.032 14.3 0.2 0.052 13.6 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 EGF79394.1 - 0.073 12.5 0.1 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF676 PF05057.14 EGF79394.1 - 0.12 11.9 0.2 0.28 10.7 0.2 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 EGF79394.1 - 0.15 11.6 0.4 4.1 6.9 0.2 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family Sec7 PF01369.20 EGF79395.1 - 6.5e-71 237.8 0.2 1.9e-70 236.3 0.2 1.9 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.10 EGF79395.1 - 6.6e-26 90.0 7.4 5.2e-23 80.7 0.1 5.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGF79395.1 - 2.9e-22 79.2 8.3 2.7e-17 63.0 4.6 3.2 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Ecm29 PF13001.7 EGF79395.1 - 0.0018 17.1 1.8 0.055 12.2 0.0 2.5 2 0 0 2 2 2 1 Proteasome stabiliser RsbU_N PF08673.10 EGF79395.1 - 0.21 11.7 2.4 1.1 9.4 0.4 3.1 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF1539 PF07560.11 EGF79395.1 - 0.85 9.7 4.2 3.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Sec7_N PF12783.7 EGF79395.1 - 2.1 8.3 5.4 2.6 7.9 0.0 3.4 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Utp12 PF04003.12 EGF79395.1 - 4.2 7.7 6.1 1.2 9.5 1.6 2.4 2 0 0 2 2 2 0 Dip2/Utp12 Family Sec16_C PF12931.7 EGF79396.1 - 4.7e-62 210.4 0.0 8.9e-62 209.4 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EGF79396.1 - 3.4e-15 56.7 0.0 2e-14 54.2 0.0 2.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.7 EGF79396.1 - 0.04 13.9 3.9 0.087 12.9 3.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGF79396.1 - 5.3 7.9 7.6 1.4 9.7 3.7 2.1 2 0 0 2 2 2 0 zinc-ribbon family XAP5 PF04921.14 EGF79399.1 - 0.031 14.1 0.9 0.041 13.7 0.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator MSG PF02349.15 EGF79399.1 - 0.067 13.4 7.1 0.097 12.9 7.1 1.2 1 0 0 1 1 1 0 Major surface glycoprotein DUF4246 PF14033.6 EGF79400.1 - 1e-77 262.2 0.1 1.1e-77 262.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) MDH PF02315.16 EGF79402.1 - 0.12 12.5 1.8 0.38 10.8 0.2 2.6 3 0 0 3 3 3 0 Methanol dehydrogenase beta subunit WDCP PF15390.6 EGF79402.1 - 0.55 8.5 5.3 0.8 8.0 5.3 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Keratin_2_head PF16208.5 EGF79405.1 - 0.02 15.0 15.3 0.19 11.8 9.2 2.5 2 0 0 2 2 2 0 Keratin type II head GPS2_interact PF15784.5 EGF79405.1 - 0.027 14.9 0.1 0.053 14.0 0.1 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KRTAP PF11759.8 EGF79405.1 - 0.097 13.2 21.8 0.19 12.3 13.6 2.4 2 0 0 2 2 2 0 Keratin-associated matrix DASH_Dad2 PF08654.10 EGF79405.1 - 1.3 9.5 4.9 1.2 9.6 0.6 2.8 3 1 0 3 3 3 0 DASH complex subunit Dad2 DUF1275 PF06912.11 EGF79406.1 - 3.9e-26 92.2 20.2 1.1e-25 90.8 20.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EGF79406.1 - 0.059 13.3 0.0 16 5.4 0.0 2.5 2 0 0 2 2 2 0 PIG-P SnoaL_2 PF12680.7 EGF79407.1 - 0.00038 21.0 0.1 0.00069 20.2 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain ABC_membrane PF00664.23 EGF79408.1 - 3.9e-59 200.6 26.0 3.4e-29 102.4 4.8 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGF79408.1 - 3.2e-51 173.4 0.0 1.5e-26 93.5 0.0 2.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF79408.1 - 3e-10 39.9 0.8 0.0011 18.4 0.0 3.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF79408.1 - 9.5e-08 32.1 0.3 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGF79408.1 - 3.5e-06 27.7 1.0 0.0037 17.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGF79408.1 - 7.3e-06 26.0 0.1 0.003 17.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGF79408.1 - 2.4e-05 24.0 0.4 0.095 12.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF79408.1 - 0.00033 20.6 0.2 3.4 7.4 0.1 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EGF79408.1 - 0.001 19.2 3.0 0.91 9.6 0.2 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 EGF79408.1 - 0.0023 18.0 0.8 0.051 13.6 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EGF79408.1 - 0.0071 16.8 0.2 4.1 7.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 EGF79408.1 - 0.0072 15.3 0.1 0.35 9.8 0.0 2.5 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EGF79408.1 - 0.027 14.8 0.2 9 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGF79408.1 - 0.035 13.4 0.4 2.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EGF79408.1 - 0.039 13.7 0.3 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EGF79408.1 - 0.07 12.2 0.1 15 4.5 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGF79408.1 - 0.086 12.2 0.1 10 5.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EGF79408.1 - 0.14 11.6 0.1 3.3 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EGF79408.1 - 0.18 10.7 1.0 2.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EGF79408.1 - 0.22 12.0 1.0 17 5.8 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGF79408.1 - 0.28 10.3 1.7 11 5.1 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain AIG1 PF04548.16 EGF79408.1 - 0.29 10.4 1.7 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 AIG1 family DUF1270 PF06900.11 EGF79409.1 - 3.5 8.1 9.1 1.9 8.9 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) ABC_membrane PF00664.23 EGF79410.1 - 2.1e-57 194.9 28.8 1.3e-28 100.4 1.2 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGF79410.1 - 2e-38 132.0 0.0 1.6e-21 77.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 EGF79410.1 - 7.9e-08 32.4 0.4 0.0019 18.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGF79410.1 - 3.3e-06 27.8 1.5 0.0031 18.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGF79410.1 - 4.3e-06 26.7 0.1 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGF79410.1 - 2.1e-05 24.2 0.4 0.089 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGF79410.1 - 0.00021 20.8 0.3 0.0065 15.9 0.1 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGF79410.1 - 0.00054 20.1 1.9 0.79 9.8 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 EGF79410.1 - 0.0028 17.7 0.7 0.045 13.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 EGF79410.1 - 0.0065 15.5 0.2 0.23 10.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 EGF79410.1 - 0.0079 16.0 0.2 3 7.6 0.1 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGF79410.1 - 0.035 13.2 0.1 8 5.4 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EGF79410.1 - 0.039 13.2 0.3 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGF79410.1 - 0.045 13.1 0.1 6 6.1 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EGF79410.1 - 0.047 13.4 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGF79410.1 - 0.047 14.0 0.1 8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGF79410.1 - 0.064 13.6 0.1 3.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EGF79410.1 - 0.064 12.1 1.1 2.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 EGF79410.1 - 0.22 10.7 1.6 10 5.2 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain AIG1 PF04548.16 EGF79410.1 - 0.26 10.6 1.7 1.3 8.3 0.1 2.2 2 0 0 2 2 2 0 AIG1 family DUF4246 PF14033.6 EGF79411.1 - 3.5e-85 286.8 0.4 4e-85 286.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4558 PF15104.6 EGF79412.1 - 0.2 11.7 5.1 1.7 8.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4558) RRF PF01765.19 EGF79412.1 - 0.53 10.2 4.7 2.1 8.3 0.2 2.1 2 0 0 2 2 2 0 Ribosome recycling factor Peptidase_S41 PF03572.18 EGF79413.1 - 1.9e-13 50.3 0.0 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF4246 PF14033.6 EGF79414.1 - 2.6e-30 106.0 0.1 3.2e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF928 PF06051.12 EGF79415.1 - 0.053 13.4 1.0 0.086 12.7 1.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) DED PF01335.21 EGF79415.1 - 0.053 13.8 5.0 0.037 14.3 3.1 1.8 2 0 0 2 2 2 0 Death effector domain Sec23_trunk PF04811.15 EGF79417.1 - 1e-71 241.3 0.1 1.7e-71 240.7 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGF79417.1 - 1.7e-26 92.0 0.1 3.2e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGF79417.1 - 2.9e-20 72.8 0.0 6.5e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGF79417.1 - 1.6e-15 56.8 2.2 3.4e-15 55.8 2.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGF79417.1 - 1.3e-10 41.0 0.0 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Proteasom_PSMB PF10508.9 EGF79418.1 - 1.1e-44 152.8 4.6 1.3e-44 152.6 4.6 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.6 EGF79418.1 - 0.0014 18.8 2.0 0.6 10.4 0.0 4.3 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 F-box PF00646.33 EGF79418.1 - 0.17 11.8 3.2 0.21 11.5 0.3 2.7 3 0 0 3 3 3 0 F-box domain EMP70 PF02990.16 EGF79420.1 - 4.6e-110 368.8 44.5 2e-73 247.8 14.3 2.6 1 1 1 2 2 2 2 Endomembrane protein 70 NTF2 PF02136.20 EGF79421.1 - 8.7e-30 103.8 0.4 8.7e-30 103.8 0.4 2.2 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EGF79421.1 - 0.0001 22.1 0.1 0.00019 21.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC32 PF14989.6 EGF79421.1 - 0.047 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing 32 PHC2_SAM_assoc PF16616.5 EGF79421.1 - 0.75 10.6 9.8 0.17 12.7 4.7 2.5 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 TFIIA PF03153.13 EGF79421.1 - 5.6 6.9 18.8 8.2 6.3 18.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Svf1_C PF17187.4 EGF79422.1 - 4.1e-39 134.0 0.1 6.3e-39 133.4 0.1 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EGF79422.1 - 2.1e-23 83.2 0.0 3e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain AFP_2 PF18815.1 EGF79423.1 - 0.088 13.1 0.8 2.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Med22 PF06179.12 EGF79424.1 - 4.8e-20 71.7 2.2 6.3e-20 71.3 2.2 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Pescadillo_N PF06732.11 EGF79426.1 - 1.5e-113 378.9 2.5 3.1e-113 377.9 2.5 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGF79426.1 - 3e-09 37.2 0.0 9.1e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGF79426.1 - 0.076 13.4 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Sec20 PF03908.13 EGF79426.1 - 0.27 11.2 1.6 0.62 10.0 0.0 2.4 3 0 0 3 3 3 0 Sec20 mRNA_cap_enzyme PF01331.19 EGF79427.1 - 3.1e-24 85.9 0.0 6.3e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGF79427.1 - 1.9e-09 38.1 0.1 7.2e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Ku_PK_bind PF08785.11 EGF79428.1 - 3.4e-31 107.9 0.2 1e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 EGF79428.1 - 7e-30 104.3 0.2 1.3e-29 103.3 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGF79428.1 - 1.3e-06 28.4 0.3 2.3e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGF79428.1 - 3.3e-06 27.7 0.2 1e-05 26.1 0.2 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm DUF2766 PF10964.8 EGF79428.1 - 0.0076 16.2 0.2 7.8 6.5 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2766) YabA PF06156.13 EGF79429.1 - 0.028 15.1 0.2 0.047 14.3 0.2 1.4 1 0 0 1 1 1 0 Initiation control protein YabA PRKG1_interact PF15898.5 EGF79429.1 - 0.068 14.1 2.1 0.1 13.5 1.9 1.3 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Pkinase PF00069.25 EGF79430.1 - 7.3e-59 199.3 0.0 9.2e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79430.1 - 3.2e-45 154.4 0.0 4.2e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF79430.1 - 8.7e-07 28.0 0.0 1.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF79430.1 - 1.9e-05 24.2 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF79430.1 - 0.034 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF79430.1 - 0.066 12.1 0.1 0.22 10.4 0.1 1.8 1 1 0 1 1 1 0 Haspin like kinase domain VHS PF00790.19 EGF79431.1 - 7.7e-37 126.3 1.9 1.3e-36 125.5 1.9 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.6 EGF79431.1 - 7.3e-12 45.0 0.3 1.8e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGF79431.1 - 5.7e-11 41.8 0.0 1.5e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF79431.1 - 4.6e-10 39.0 0.1 8.8e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1539 PF07560.11 EGF79431.1 - 0.0083 16.2 2.5 2.3 8.3 0.0 2.8 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1539) UIM PF02809.20 EGF79431.1 - 0.019 14.8 3.7 0.04 13.8 3.7 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif RRM_1 PF00076.22 EGF79432.1 - 1.8e-22 78.9 0.0 5.5e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF79432.1 - 6.4e-06 25.9 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGF79432.1 - 0.00093 19.2 0.0 0.94 9.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 EGF79432.1 - 0.0023 17.8 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) IFT20 PF14931.6 EGF79433.1 - 2.8e-28 98.5 4.6 3e-28 98.4 4.6 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 BSD PF03909.17 EGF79434.1 - 8.3e-19 67.4 0.0 3.4e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EGF79434.1 - 2.7e-17 62.8 0.0 6.2e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain 2-Hacid_dh_C PF02826.19 EGF79435.1 - 1e-50 171.5 0.0 1.6e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGF79435.1 - 9.7e-36 122.4 0.0 1.3e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGF79435.1 - 3.1e-05 24.2 0.2 9e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 EGF79435.1 - 0.017 15.6 0.0 0.27 11.8 0.0 2.6 2 1 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 EGF79435.1 - 0.032 14.3 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EGF79435.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 ACT domain GHL6 PF14871.6 EGF79435.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Ribosomal_S28e PF01200.18 EGF79436.1 - 1.2e-32 111.7 1.9 1.3e-32 111.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 EGF79436.1 - 0.019 15.3 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal EMC3_TMCO1 PF01956.16 EGF79437.1 - 7e-52 175.6 3.1 9.7e-52 175.1 3.1 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Fumble PF03630.14 EGF79438.1 - 1.4e-137 458.4 0.9 2.1e-137 457.7 0.9 1.3 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 EGF79438.1 - 3.2e-36 125.0 0.0 4.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 CHIPS PF11434.8 EGF79438.1 - 0.11 12.3 0.2 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS PapD_N PF00345.20 EGF79439.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain SCIFF PF13165.6 EGF79439.1 - 0.41 10.6 2.4 18 5.4 0.3 3.0 3 0 0 3 3 3 0 Six-cysteine peptide SCIFF Peptidase_C97 PF05903.14 EGF79440.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain Eclosion PF04736.12 EGF79440.1 - 0.064 13.0 1.3 0.11 12.2 0.2 1.9 3 0 0 3 3 3 0 Eclosion hormone DUF5105 PF17118.5 EGF79442.1 - 0.021 14.6 0.1 0.051 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) DUF2870 PF11069.8 EGF79447.1 - 0.0018 18.6 5.4 0.003 17.9 0.3 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2870) FBPase_2 PF06874.11 EGF79447.1 - 0.0037 15.6 0.5 0.0048 15.2 0.1 1.3 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Spectrin PF00435.21 EGF79447.1 - 0.022 15.2 4.2 1 9.9 0.9 2.3 2 0 0 2 2 2 0 Spectrin repeat Phage_GP20 PF06810.11 EGF79447.1 - 0.024 14.4 5.1 0.96 9.2 0.4 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 EGF79447.1 - 0.026 14.8 3.5 0.56 10.5 0.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spem1 PF15670.5 EGF79447.1 - 4.6 6.7 7.9 0.82 9.2 3.2 2.0 1 1 0 2 2 2 0 Spermatid maturation protein 1 Pneumo_att_G PF05539.11 EGF79447.1 - 5.8 6.4 10.1 7.9 6.0 10.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GLTSCR1 PF15249.6 EGF79448.1 - 8e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein 2-oxoacid_dh PF00198.23 EGF79449.1 - 6.8e-83 277.7 0.1 9.1e-83 277.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGF79449.1 - 1.7e-17 63.0 0.1 3.2e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGF79449.1 - 1.2e-13 51.2 0.3 2.5e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 e3 binding domain Molybdopterin PF00384.22 EGF79451.1 - 3.7e-59 200.8 0.0 9.4e-32 110.5 0.0 2.3 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EGF79451.1 - 2.9e-18 65.7 0.2 6.9e-18 64.5 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EGF79451.1 - 5.1e-17 61.1 0.1 5.1e-17 61.1 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 EGF79451.1 - 1.8e-15 57.4 0.1 8.6e-15 55.2 0.1 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 EGF79451.1 - 1.8e-07 31.0 0.5 1.8e-07 31.0 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EGF79451.1 - 0.022 14.5 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EGF79451.1 - 0.18 11.7 1.3 4.4 7.3 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EGF79451.1 - 0.22 11.6 0.7 30 4.8 0.0 3.0 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster Tub PF01167.18 EGF79453.1 - 6.8e-49 166.8 0.0 8.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Tub family Cofilin_ADF PF00241.20 EGF79454.1 - 2e-22 79.2 0.1 2.4e-22 79.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HAD PF12710.7 EGF79455.1 - 8.2e-19 68.7 0.1 1.1e-18 68.4 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGF79455.1 - 7.3e-15 55.8 0.1 9.6e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGF79455.1 - 3e-09 37.0 0.3 5.4e-08 32.9 0.4 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGF79455.1 - 9.9e-06 25.1 0.0 0.0018 17.8 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.6 EGF79455.1 - 0.0024 18.0 0.3 3.7 7.6 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 EGF79455.1 - 0.031 13.8 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 EGF79455.1 - 0.045 13.3 0.2 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase UQ_con PF00179.26 EGF79456.1 - 3e-38 130.6 0.1 3.7e-38 130.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGF79456.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain DNA_mis_repair PF01119.19 EGF79457.1 - 2.9e-22 78.6 0.0 8.5e-22 77.1 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EGF79457.1 - 2.9e-21 75.8 0.2 4.5e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 MutL C terminal dimerisation domain LIM PF00412.22 EGF79458.1 - 1.6e-56 188.3 55.2 5.7e-13 48.9 1.6 5.1 5 0 0 5 5 5 5 LIM domain Sgf11 PF08209.11 EGF79458.1 - 0.037 13.6 0.1 0.037 13.6 0.1 6.2 9 0 0 9 9 9 0 Sgf11 (transcriptional regulation protein) Aminotran_5 PF00266.19 EGF79459.1 - 4e-15 55.7 0.0 5.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.32 EGF79460.1 - 1.1e-60 200.1 26.6 9.3e-11 42.1 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79460.1 - 1.5e-23 82.9 0.4 0.00032 20.9 0.1 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF79460.1 - 1.9e-11 43.4 4.0 0.0081 14.9 0.1 4.9 2 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EGF79460.1 - 2.3e-11 43.9 0.1 7.9e-06 25.9 0.0 3.2 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGF79460.1 - 1.3e-08 34.5 0.1 7.6e-05 22.2 0.0 3.6 1 1 3 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 EGF79460.1 - 4.8e-06 25.8 1.2 0.25 10.3 0.6 3.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EGF79460.1 - 0.00025 20.1 0.2 0.28 10.1 0.0 3.5 1 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 EGF79460.1 - 0.0014 17.8 0.1 0.05 12.6 0.0 2.9 2 1 1 4 4 4 2 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 EGF79460.1 - 0.0025 16.9 0.4 0.2 10.7 0.4 2.2 1 1 1 2 2 2 1 Coatomer WD associated region Frtz PF11768.8 EGF79460.1 - 0.003 16.0 0.0 0.013 13.8 0.0 1.9 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 EGF79460.1 - 0.0064 16.4 2.9 0.76 9.8 0.1 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cation_ATPase_C PF00689.21 EGF79461.1 - 0.0027 17.5 0.9 0.0027 17.5 0.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGF79461.1 - 0.13 12.5 0.0 6.7 6.9 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PI-PLC-X PF00388.19 EGF79461.1 - 0.15 11.6 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain E1-E2_ATPase PF00122.20 EGF79461.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.6 3 0 0 3 3 3 0 E1-E2 ATPase DUF1279 PF06916.13 EGF79463.1 - 1.7e-06 28.5 0.5 2.4e-06 28.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PH PF00169.29 EGF79464.1 - 0.0026 18.2 0.0 0.0073 16.8 0.0 1.8 1 0 0 1 1 1 1 PH domain HALZ PF02183.18 EGF79464.1 - 0.011 15.9 0.4 0.034 14.4 0.4 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper UPF0184 PF03670.13 EGF79464.1 - 0.089 13.2 1.5 2.5 8.6 0.2 3.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) ATG_C PF09333.11 EGF79464.1 - 0.098 13.0 0.1 5.8 7.3 0.0 3.5 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain DUF922 PF06037.11 EGF79464.1 - 0.48 10.2 5.9 2 8.2 0.1 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF922) Pup PF05639.11 EGF79464.1 - 8.1 7.4 8.3 0.43 11.5 0.3 3.1 4 0 0 4 4 4 0 Pup-like protein DUF2205 PF10224.9 EGF79464.1 - 9 6.4 9.8 16 5.6 0.1 4.4 3 0 0 3 3 3 0 Short coiled-coil protein zf-C4H2 PF10146.9 EGF79465.1 - 1.6e-12 48.2 0.2 2e-12 47.9 0.2 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein CheZ PF04344.13 EGF79465.1 - 0.0037 17.2 4.0 0.0058 16.6 4.0 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ HALZ PF02183.18 EGF79465.1 - 0.059 13.6 1.2 0.16 12.2 1.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2968 PF11180.8 EGF79465.1 - 0.15 11.7 8.4 0.24 11.0 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) H-kinase_dim PF02895.14 EGF79465.1 - 1 9.8 4.4 2.9 8.3 3.4 2.2 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Baculo_PEP_C PF04513.12 EGF79465.1 - 4 7.5 11.1 7.7 6.6 2.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54 PF13874.6 EGF79465.1 - 7 6.8 10.9 7.6 6.6 9.1 1.8 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 U1snRNP70_N PF12220.8 EGF79466.1 - 2.6e-20 72.8 0.2 2.6e-20 72.8 0.2 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EGF79466.1 - 1.1e-19 70.0 0.1 1.8e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF79466.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Bromodomain PF00439.25 EGF79467.1 - 6.2e-23 80.7 0.1 1.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 EGF79467.1 - 0.0012 18.7 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF79467.1 - 0.019 15.2 0.1 0.05 13.8 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Gly_acyl_tr_C PF08444.10 EGF79468.1 - 0.0015 18.8 0.1 0.01 16.0 0.0 2.5 2 1 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Scm3 PF10384.9 EGF79469.1 - 3.6e-19 68.2 0.0 9.1e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Vfa1 PF08432.10 EGF79470.1 - 1.1e-15 58.4 10.4 6.7e-12 46.1 0.4 2.2 1 1 1 2 2 2 2 AAA-ATPase Vps4-associated protein 1 MutL_C PF08676.11 EGF79470.1 - 0.0016 18.2 0.2 0.0016 18.2 0.2 2.3 3 1 0 3 3 3 1 MutL C terminal dimerisation domain TPR_2 PF07719.17 EGF79471.1 - 1.1e-06 28.3 1.8 0.00049 20.0 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF79471.1 - 6.6e-05 22.8 0.0 0.0024 18.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF79471.1 - 9.6e-05 22.0 2.0 0.0067 16.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF79471.1 - 0.00015 22.0 0.2 0.00022 21.4 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGF79471.1 - 0.00037 20.6 0.2 0.077 13.2 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGF79471.1 - 0.0016 18.9 0.1 0.99 10.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF79471.1 - 0.0023 18.6 0.1 0.15 13.0 0.0 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF79471.1 - 0.026 15.2 0.1 0.038 14.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF79471.1 - 0.036 14.3 0.5 3.8 7.9 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF79471.1 - 0.075 13.1 0.1 3.3 7.9 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat BCAS2 PF05700.11 EGF79472.1 - 3.6e-51 173.8 6.4 4e-51 173.7 6.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) FapA PF03961.13 EGF79472.1 - 0.093 11.3 3.5 0.11 11.0 3.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3037 PF11236.8 EGF79472.1 - 0.1 13.0 1.7 0.16 12.4 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) APG6_N PF17675.1 EGF79472.1 - 0.2 12.2 9.3 0.15 12.6 4.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Kinesin_assoc PF16183.5 EGF79472.1 - 0.38 10.9 3.2 0.51 10.5 3.1 1.3 1 1 0 1 1 1 0 Kinesin-associated YabA PF06156.13 EGF79472.1 - 2.4 8.8 4.8 1.7 9.4 0.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 EGF79472.1 - 3.6 7.6 7.6 18 5.4 0.8 3.2 1 1 1 3 3 3 0 Short coiled-coil protein Abhydrolase_1 PF00561.20 EGF79473.1 - 7.4e-50 170.0 0.0 8.8e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF79473.1 - 0.052 14.2 0.0 0.099 13.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGF79473.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein rRNA_processing PF08524.11 EGF79474.1 - 2.1e-07 31.1 10.1 3e-07 30.6 10.1 1.4 1 1 0 1 1 1 1 rRNA processing KASH_CCD PF14662.6 EGF79474.1 - 0.00094 19.1 2.6 0.0012 18.7 2.6 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SRAP PF02586.14 EGF79475.1 - 6.9e-33 114.0 0.8 9.5e-33 113.6 0.2 1.5 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) DUF2362 PF10154.9 EGF79476.1 - 3.7e-66 224.1 21.8 2.1e-24 86.4 0.1 4.0 2 1 1 3 3 3 3 Uncharacterized conserved protein (DUF2362) UBA PF00627.31 EGF79476.1 - 0.00049 19.9 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain NUC153 PF08159.12 EGF79477.1 - 1.3e-17 63.2 10.7 9.2e-15 54.2 0.1 4.2 4 0 0 4 4 4 3 NUC153 domain SET PF00856.28 EGF79478.1 - 2.3e-05 24.9 0.0 5.9e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGF79478.1 - 0.015 15.4 3.0 0.015 15.4 3.0 3.6 4 0 0 4 4 4 0 MYND finger A2L_zn_ribbon PF08792.10 EGF79478.1 - 4 7.3 7.3 23 4.9 0.4 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain NicO PF03824.16 EGF79478.1 - 7.1 5.9 6.9 15 4.8 6.9 1.5 1 0 0 1 1 1 0 High-affinity nickel-transport protein VPS9 PF02204.18 EGF79479.1 - 1.7e-23 82.8 0.0 4e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGF79479.1 - 0.00012 22.3 0.0 0.00035 20.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Acetyltransf_1 PF00583.25 EGF79480.1 - 5.8e-14 52.3 0.1 7.6e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF79480.1 - 1e-06 29.1 0.1 1.5e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGF79480.1 - 1e-05 25.5 0.1 1.3e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PGP_phosphatase PF09419.10 EGF79481.1 - 1.3e-49 168.1 0.0 1.6e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase HAD_2 PF13419.6 EGF79481.1 - 6.1e-07 29.7 0.0 2.1e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGF79481.1 - 6.3e-06 26.2 0.0 1.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGF79481.1 - 0.00035 20.9 0.0 0.16 12.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DRMBL PF07522.14 EGF79482.1 - 5.6e-28 97.3 0.0 9e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGF79482.1 - 4.7e-06 26.2 0.1 7.5e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGF79482.1 - 0.0025 17.9 0.1 0.0054 16.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EGF79482.1 - 0.05 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Metallophos PF00149.28 EGF79483.1 - 9.3e-36 124.2 0.1 1.1e-35 123.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGF79483.1 - 0.025 15.0 0.2 0.061 13.8 0.2 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGF79483.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Arrestin_C PF02752.22 EGF79484.1 - 1.4e-16 61.2 2.0 5.9e-11 43.0 0.1 3.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 EGF79484.1 - 5.1e-06 25.9 0.7 0.015 14.5 0.0 2.3 2 0 0 2 2 2 2 Rgp1 WAC_Acf1_DNA_bd PF10537.9 EGF79485.1 - 3.5e-32 110.9 0.2 7.7e-32 109.8 0.2 1.6 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EGF79485.1 - 3.4e-21 75.6 0.0 3.4e-21 75.6 0.0 2.7 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EGF79485.1 - 1.5e-08 34.8 0.2 2.8e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGF79485.1 - 4.7e-06 26.0 0.1 0.00018 20.9 0.1 2.6 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 TPR_8 PF13181.6 EGF79486.1 - 3.8e-08 32.9 0.5 1.2 9.6 0.0 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF79486.1 - 6.7e-08 32.4 0.1 0.0018 18.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF79486.1 - 4.9e-07 29.4 2.5 10 6.5 0.1 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF79486.1 - 3.7e-06 27.3 1.3 0.002 18.6 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF79486.1 - 0.00012 21.8 5.5 12 5.9 0.0 6.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF79486.1 - 0.00052 20.2 0.0 0.78 10.1 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF79486.1 - 0.00065 20.3 0.0 62 4.8 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.10 EGF79486.1 - 0.001 18.6 0.2 0.17 11.3 0.3 2.9 1 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like NARP1 PF12569.8 EGF79486.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EGF79486.1 - 0.014 15.6 0.7 0.45 10.8 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NHR2 PF08788.11 EGF79486.1 - 0.02 14.6 0.2 0.042 13.6 0.2 1.5 1 0 0 1 1 1 0 NHR2 domain like Ribosomal_L19 PF01245.20 EGF79487.1 - 4.4e-11 42.7 0.3 8.2e-11 41.8 0.3 1.4 1 1 0 1 1 1 1 Ribosomal protein L19 Kelch_4 PF13418.6 EGF79488.1 - 1.2e-11 44.4 1.3 9.9e-05 22.3 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF79488.1 - 2e-07 31.0 2.1 0.0084 16.4 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EGF79488.1 - 1.1e-05 25.6 3.4 0.16 12.3 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGF79488.1 - 3e-05 23.9 3.5 0.011 15.7 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Myotub-related PF06602.14 EGF79489.1 - 5.6e-144 479.4 0.0 6.5e-144 479.2 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 EGF79489.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF79489.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGF79489.1 - 0.045 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Myb_DNA-bind_3 PF12776.7 EGF79490.1 - 1.5e-17 64.3 1.6 2.8e-17 63.5 0.7 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGF79490.1 - 0.00021 21.6 0.0 0.00058 20.2 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain HALZ PF02183.18 EGF79490.1 - 0.015 15.5 0.8 0.051 13.8 0.8 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper Myb_DNA-bind_5 PF13873.6 EGF79490.1 - 0.075 13.1 0.2 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-C2H2 PF00096.26 EGF79491.1 - 0.4 11.2 2.9 0.97 10.0 2.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_M28 PF04389.17 EGF79492.1 - 2.4e-32 112.3 0.2 4.2e-32 111.4 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGF79492.1 - 1e-07 31.9 0.0 2.1e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 REC1 PF18501.1 EGF79492.1 - 0.017 15.0 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Alpha helical recognition lobe domain Nicastrin PF05450.15 EGF79492.1 - 0.055 12.9 0.0 0.32 10.4 0.0 2.2 3 0 0 3 3 3 0 Nicastrin Peptidase_M28 PF04389.17 EGF79493.1 - 3.7e-30 105.1 0.0 5.9e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGF79493.1 - 1.7e-09 37.7 0.0 3.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EGF79493.1 - 0.021 14.3 0.0 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 Nicastrin Iso_dh PF00180.20 EGF79494.1 - 2.7e-100 335.9 0.0 3e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EGF79494.1 - 0.039 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 IQ PF00612.27 EGF79495.1 - 0.0036 17.0 0.6 0.0092 15.7 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3519 PF12033.8 EGF79495.1 - 7.3 7.1 8.0 3.2 8.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3519) Snf7 PF03357.21 EGF79497.1 - 7.5e-46 155.9 15.2 8.9e-46 155.6 15.2 1.0 1 0 0 1 1 1 1 Snf7 Stork_head PF10264.9 EGF79497.1 - 0.029 14.5 0.3 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Endotoxin_N PF03945.14 EGF79497.1 - 0.1 12.3 5.5 4.9 6.8 2.9 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain SelA PF03841.13 EGF79497.1 - 0.18 10.8 2.4 0.28 10.1 2.3 1.5 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase AP1AR PF15745.5 EGF79497.1 - 0.75 9.4 7.7 0.44 10.1 6.1 1.5 1 1 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF4349 PF14257.6 EGF79497.1 - 1.9 7.8 6.4 1.2 8.5 3.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) FlaC_arch PF05377.11 EGF79497.1 - 2 8.9 9.8 9.6 6.7 0.2 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) CLTH PF10607.9 EGF79498.1 - 6.4e-30 104.0 0.2 9e-30 103.5 0.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGF79498.1 - 2.1e-05 24.3 2.4 2.9e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 LisH DUF2370 PF10176.9 EGF79499.1 - 4.2e-52 177.0 0.4 3e-43 148.1 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) DUF202 PF02656.15 EGF79499.1 - 0.82 10.2 3.3 12 6.4 3.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Chibby PF14645.6 EGF79500.1 - 0.17 12.3 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Chibby family PI3_PI4_kinase PF00454.27 EGF79501.1 - 2e-40 139.2 0.0 9.8e-38 130.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGF79501.1 - 1.4e-19 70.2 0.0 3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) GCD14 PF08704.10 EGF79502.1 - 9.8e-88 294.0 0.0 1.5e-87 293.4 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EGF79502.1 - 2.1e-05 24.4 0.0 5.4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EGF79502.1 - 3.4e-05 23.7 0.0 5.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EGF79502.1 - 0.035 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGF79502.1 - 0.047 14.4 0.0 0.084 13.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 EGF79502.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term DUF2684 PF10885.8 EGF79502.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) Methyltransf_4 PF02390.17 EGF79502.1 - 0.19 11.2 0.0 0.45 10.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Nup188 PF10487.9 EGF79503.1 - 2.5e-59 201.2 1.7 2.7e-29 101.8 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EGF79503.1 - 0.00028 19.9 3.9 0.00065 18.6 3.9 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Acetyltransf_1 PF00583.25 EGF79504.1 - 2.6e-09 37.3 0.0 3e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF79504.1 - 0.00011 22.5 0.1 0.00014 22.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGF79504.1 - 0.00036 20.5 0.1 0.00043 20.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGF79504.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase LRR_8 PF13855.6 EGF79506.1 - 4.8e-13 48.7 17.7 2.3e-09 36.9 5.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGF79506.1 - 1.8e-10 40.9 18.6 8.3e-06 26.1 1.1 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF79506.1 - 3.7e-07 29.8 21.2 0.057 14.0 0.2 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRRNT_2 PF08263.12 EGF79506.1 - 0.074 13.4 2.0 0.2 12.0 2.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 EGF79506.1 - 0.15 11.5 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EGF79506.1 - 0.85 9.8 12.6 1.2 9.4 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat ALMT PF11744.8 EGF79507.1 - 1.5e-15 57.0 15.1 1.5e-15 57.0 15.1 2.3 2 1 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 EGF79507.1 - 1.2e-13 51.3 9.7 1.6e-13 50.9 8.0 2.1 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGF79507.1 - 5.4e-13 48.4 5.6 5.4e-13 48.4 5.6 1.8 2 0 0 2 2 2 1 Fusaric acid resistance protein family FUSC-like PF12805.7 EGF79507.1 - 2.8 6.9 6.1 0.58 9.2 2.0 2.0 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS ArAE_1 PF06081.11 EGF79507.1 - 5.1 7.2 8.4 32 4.7 0.1 2.7 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 CHCH PF06747.13 EGF79508.1 - 0.00019 21.5 7.8 0.00019 21.5 7.8 2.3 2 0 0 2 2 2 1 CHCH domain COX6B PF02297.17 EGF79508.1 - 0.097 12.9 12.8 0.084 13.1 10.5 1.8 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EGF79508.1 - 0.27 11.6 10.6 3 8.2 0.4 3.1 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGF79508.1 - 0.55 10.3 11.7 2.6 8.1 5.8 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EGF79508.1 - 3.3 7.8 13.0 2.3 8.3 5.1 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like BCDHK_Adom3 PF10436.9 EGF79509.1 - 8.3e-40 136.3 0.3 1.4e-39 135.5 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGF79509.1 - 1e-08 35.6 0.0 3.3e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGF79509.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MMR_HSR1_C PF08438.10 EGF79510.1 - 4.6e-35 120.6 0.0 7.1e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGF79510.1 - 1.9e-21 76.2 0.0 1e-20 73.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF79510.1 - 1.3e-08 34.5 0.4 1.9e-07 30.7 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF79510.1 - 0.0011 19.1 0.1 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGF79510.1 - 0.014 15.3 0.1 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase YchF-GTPase_C PF06071.13 EGF79510.1 - 0.039 14.1 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF933) ATP_bind_1 PF03029.17 EGF79510.1 - 0.047 13.5 1.6 4.2 7.1 0.1 2.9 2 2 1 3 3 3 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 EGF79510.1 - 0.082 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Spt20 PF12090.8 EGF79511.1 - 1.1e-12 48.1 0.4 1.1e-12 48.1 0.4 2.5 2 1 0 2 2 2 1 Spt20 family Cytochrom_B561 PF03188.16 EGF79513.1 - 2.8e-12 46.9 4.2 2.8e-12 46.9 4.2 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EGF79513.1 - 9e-06 25.9 2.5 9e-06 25.9 2.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) DSPc PF00782.20 EGF79514.1 - 1.8e-11 44.0 0.2 1.8e-11 44.0 0.2 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGF79514.1 - 4.4e-11 42.7 1.7 7.9e-11 41.9 1.7 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EGF79514.1 - 0.0053 16.4 0.1 0.0053 16.4 0.1 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase START PF01852.19 EGF79515.1 - 7.9e-17 61.4 0.2 1.9e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 START domain Mito_carr PF00153.27 EGF79516.1 - 4.2e-15 55.4 0.1 0.00062 19.6 0.0 4.6 4 1 0 4 4 4 4 Mitochondrial carrier protein CKS PF01111.19 EGF79517.1 - 8.2e-30 102.9 1.8 1.3e-29 102.3 1.8 1.3 1 1 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ABC_tran PF00005.27 EGF79518.1 - 1.7e-17 64.2 0.0 2.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF79518.1 - 0.00021 21.2 0.1 0.0005 20.0 0.1 1.7 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGF79518.1 - 0.061 13.6 0.0 0.92 9.8 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EGF79518.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain adh_short PF00106.25 EGF79519.1 - 1.3e-35 122.6 0.2 5.2e-27 94.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF79519.1 - 6e-23 81.6 0.1 2.3e-21 76.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF79519.1 - 9e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF79519.1 - 0.00028 20.5 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGF79519.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGF79519.1 - 0.044 13.2 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EGF79519.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGF79519.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Chitin_synth_2 PF03142.15 EGF79520.1 - 1.6e-226 753.0 0.9 2.4e-226 752.4 0.9 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGF79520.1 - 3.3e-99 333.0 0.0 4.5e-99 332.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EGF79520.1 - 1.5e-17 63.2 0.0 1.2e-16 60.4 0.0 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGF79520.1 - 4.5e-13 49.6 3.3 1.1e-12 48.2 3.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF79520.1 - 2.8e-10 40.5 0.1 6.9e-09 35.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGF79520.1 - 0.00066 19.5 0.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGF79520.1 - 0.029 13.9 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 SSP160 PF06933.11 EGF79521.1 - 0.35 9.0 13.5 0.55 8.4 13.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DNA_pol_phi PF04931.13 EGF79521.1 - 1.8 6.5 8.5 2.5 6.1 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi MA3 PF02847.17 EGF79522.1 - 3.6e-26 91.3 0.2 1.1e-25 89.8 0.2 1.9 1 0 0 1 1 1 1 MA3 domain MIF4G_like PF09088.11 EGF79522.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 MIF4G like Peptidase_M16 PF00675.20 EGF79523.1 - 8.7e-51 171.8 0.2 4.3e-50 169.6 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGF79523.1 - 6.2e-41 140.4 0.0 4.2e-40 137.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain TGT PF01702.18 EGF79524.1 - 1.5e-143 478.2 0.1 1.8e-143 477.9 0.1 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase HAUS6_N PF14661.6 EGF79525.1 - 7.3e-10 38.8 0.4 1.1e-09 38.3 0.4 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Zn_clus PF00172.18 EGF79526.1 - 0.001 19.1 14.0 0.001 19.1 14.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMC_Nse1 PF07574.13 EGF79527.1 - 5.7e-24 85.1 1.3 2.7e-22 79.6 1.3 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EGF79527.1 - 0.00022 21.5 11.7 0.00038 20.7 11.7 1.4 1 0 0 1 1 1 1 RING-like domain Csm1_N PF18504.1 EGF79527.1 - 0.059 13.7 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 Csm1 N-terminal domain C1_2 PF03107.16 EGF79527.1 - 0.4 11.0 4.5 0.11 12.9 0.9 1.9 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H PF13771.6 EGF79527.1 - 2.5 8.4 9.6 7.5 6.9 9.5 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 EGF79527.1 - 3 8.3 7.3 6.1 7.3 7.3 1.6 1 0 0 1 1 1 0 Ring finger domain A_deaminase PF00962.22 EGF79528.1 - 1.6e-31 109.9 0.1 1.8e-31 109.7 0.1 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EGF79528.1 - 1.2e-05 24.8 0.2 1.7e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase family PTH2 PF01981.16 EGF79529.1 - 1.7e-14 54.1 0.1 2.1e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Rota_NS6 PF04866.12 EGF79529.1 - 0.081 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 zf-RING_UBOX PF13445.6 EGF79530.1 - 1.4e-10 41.0 8.6 4.3e-10 39.5 8.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGF79530.1 - 1.5e-07 31.1 8.7 1.5e-07 31.1 8.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGF79530.1 - 1e-06 28.8 13.5 3.5e-06 27.1 13.5 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGF79530.1 - 4.3e-06 26.5 15.8 1.5e-05 24.8 15.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF79530.1 - 0.00012 21.8 12.2 0.00031 20.5 12.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF79530.1 - 0.00023 21.1 12.9 0.00023 21.1 12.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGF79530.1 - 0.00023 21.4 13.2 0.00076 19.8 13.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 EGF79530.1 - 0.00057 19.7 8.9 0.0022 17.8 8.9 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3450 PF11932.8 EGF79530.1 - 0.0082 15.5 3.1 0.0082 15.5 3.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) U-box PF04564.15 EGF79530.1 - 0.022 14.9 0.1 0.066 13.4 0.1 1.9 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.6 EGF79530.1 - 0.046 13.6 14.7 2.1 8.3 8.6 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Spc7 PF08317.11 EGF79530.1 - 0.14 11.0 12.0 0.0086 15.0 6.5 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein CHDCT2 PF08074.11 EGF79530.1 - 0.34 11.1 5.2 0.1 12.7 1.5 2.0 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain zf-rbx1 PF12678.7 EGF79530.1 - 0.47 10.8 9.9 3.4 8.0 9.8 2.6 1 1 1 2 2 2 0 RING-H2 zinc finger domain FYVE PF01363.21 EGF79530.1 - 1.3 9.2 9.6 9.9 6.4 9.6 2.6 1 1 0 1 1 1 0 FYVE zinc finger zf-MIZ PF02891.20 EGF79530.1 - 2.4 7.9 13.3 1 9.1 1.0 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger YdjO PF14169.6 EGF79530.1 - 4.1 7.2 7.8 0.2 11.4 0.3 2.7 3 0 0 3 3 3 0 Cold-inducible protein YdjO DUF4472 PF14739.6 EGF79530.1 - 7.9 7.3 14.7 1.1 10.0 1.6 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) GalKase_gal_bdg PF10509.9 EGF79531.1 - 9.6e-23 79.5 0.0 2.1e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGF79531.1 - 1e-13 51.4 0.2 3e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGF79531.1 - 2e-11 43.9 1.9 4e-11 43.0 1.9 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain HTH_17 PF12728.7 EGF79531.1 - 0.065 13.4 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Ank_2 PF12796.7 EGF79532.1 - 8.4e-11 42.3 4.5 0.00023 21.7 2.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF79532.1 - 3.8e-08 33.7 3.9 6.5e-05 23.4 0.0 4.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF79532.1 - 7.4e-07 29.0 1.8 0.071 13.7 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGF79532.1 - 9e-07 29.1 4.7 0.00082 19.6 0.4 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF79532.1 - 8.5e-06 26.0 1.9 0.2 12.2 0.2 3.9 3 1 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 EGF79532.1 - 0.0012 18.6 1.3 0.0038 17.0 0.1 2.3 2 1 0 2 2 2 1 KilA-N domain PRKG1_interact PF15898.5 EGF79532.1 - 4.2 8.3 6.1 9.7 7.2 1.4 3.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain UCH PF00443.29 EGF79533.1 - 2.2e-33 115.9 4.7 2.2e-33 115.9 4.7 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EGF79533.1 - 1.8e-15 56.6 0.8 1.4e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 EGF79533.1 - 0.00019 21.2 7.0 0.12 12.0 0.2 2.8 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EGF79533.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.9 1 0 0 1 1 1 0 PUB domain Spectrin PF00435.21 EGF79533.1 - 0.19 12.2 1.1 6.7 7.2 0.2 2.6 2 0 0 2 2 2 0 Spectrin repeat TFIIE_alpha PF02002.17 EGF79535.1 - 0.097 12.5 0.4 6.2 6.7 0.1 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit WD40 PF00400.32 EGF79536.1 - 5e-46 153.7 11.0 8.2e-09 36.0 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79536.1 - 5.6e-14 52.2 0.3 0.039 14.2 0.1 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF79536.1 - 4.7e-08 32.1 0.9 0.18 10.4 0.0 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF79536.1 - 1.2e-05 24.4 3.1 0.5 9.3 0.0 4.6 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGF79536.1 - 5.4e-05 22.1 0.1 0.027 13.2 0.0 3.5 1 1 2 4 4 4 2 Nup133 N terminal like Frtz PF11768.8 EGF79536.1 - 0.00012 20.5 0.0 0.00052 18.5 0.0 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EGF79536.1 - 0.0018 17.2 1.2 0.0034 16.4 0.0 2.0 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain HPS3_N PF14761.6 EGF79536.1 - 0.0041 16.7 0.0 0.059 12.9 0.0 2.4 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 EGF79536.1 - 0.0084 15.5 0.0 3 7.1 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 EGF79536.1 - 0.069 13.7 0.2 15 6.2 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Utp8 PF10395.9 EGF79536.1 - 0.23 9.9 0.0 2.2 6.7 0.0 1.9 1 1 1 2 2 2 0 Utp8 family dsDNA_bind PF01984.20 EGF79537.1 - 4.8e-35 120.2 9.4 5.8e-35 119.9 9.4 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF5531 PF17671.1 EGF79537.1 - 0.1 12.5 1.0 0.17 11.8 1.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5531) TFIIS_C PF01096.18 EGF79538.1 - 7.8e-13 48.0 10.6 1.5e-12 47.1 5.9 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGF79538.1 - 2.7e-05 23.9 0.2 2.7e-05 23.9 0.2 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_17 PF17120.5 EGF79538.1 - 0.31 10.7 8.1 1 9.0 0.3 3.1 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Zn_Tnp_IS1595 PF12760.7 EGF79538.1 - 0.41 10.7 8.3 0.29 11.1 3.4 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Dof PF02701.15 EGF79538.1 - 0.89 9.7 10.0 0.61 10.3 5.2 2.5 2 1 0 2 2 2 0 Dof domain, zinc finger Spt20 PF12090.8 EGF79539.1 - 7.4e-13 48.6 0.3 7.4e-13 48.6 0.3 2.4 2 1 0 2 2 2 1 Spt20 family GCP_N_terminal PF17681.1 EGF79540.1 - 1.8e-81 274.2 0.9 1.8e-81 274.2 0.9 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGF79540.1 - 2.1e-79 267.2 8.3 4.3e-79 266.2 8.3 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal RhoGEF PF00621.20 EGF79541.1 - 1.2e-42 146.2 0.5 1.2e-42 146.2 0.5 1.9 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGF79541.1 - 2e-18 66.3 12.8 2e-18 66.3 12.8 2.7 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 EGF79541.1 - 0.0019 18.6 0.0 0.0059 17.1 0.0 1.8 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 EGF79541.1 - 0.0038 17.4 24.1 0.025 14.8 3.5 2.7 3 0 0 3 3 3 2 FYVE-type zinc finger PH_13 PF16652.5 EGF79541.1 - 0.022 14.5 0.4 0.2 11.5 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PI3K_P85_iSH2 PF16454.5 EGF79541.1 - 0.076 12.6 0.2 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain tRNA-synt_1g PF09334.11 EGF79542.1 - 5.2e-152 506.1 0.4 6.9e-152 505.7 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 EGF79542.1 - 9.8e-13 48.1 1.7 2.4e-12 46.8 1.7 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 EGF79542.1 - 2.7e-10 39.2 1.1 3.9e-07 28.7 0.0 3.3 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGF79542.1 - 0.061 13.3 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGF79542.1 - 0.07 12.5 0.1 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Thioredoxin PF00085.20 EGF79543.1 - 2.9e-05 24.0 0.0 5.4e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin ProQ_C PF17516.2 EGF79543.1 - 0.0076 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 ProQ C-terminal domain DUF1077 PF06417.12 EGF79544.1 - 8.4e-42 141.9 4.8 1.1e-41 141.5 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) GST_C_2 PF13410.6 EGF79545.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGF79545.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGF79545.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CDC37_N PF03234.14 EGF79545.1 - 4.5 8.2 6.4 3.5 8.6 3.2 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Myb_DNA-binding PF00249.31 EGF79546.1 - 1.3e-09 38.1 0.1 3.9e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGF79546.1 - 2.3e-09 36.9 9.9 2.3e-09 36.9 9.9 1.7 2 0 0 2 2 2 1 Zinc finger, ZZ type SWIRM PF04433.17 EGF79546.1 - 5.7e-08 33.0 0.1 1.6e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EGF79546.1 - 0.00051 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tyrosinase PF00264.20 EGF79547.1 - 1.4e-35 123.6 2.4 1.6e-34 120.1 2.4 2.2 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 EGF79548.1 - 2.4e-34 119.5 12.0 1.6e-33 116.9 6.6 2.7 2 1 0 2 2 2 1 Common central domain of tyrosinase Chitin_bind_1 PF00187.19 EGF79548.1 - 8.3e-09 35.8 36.4 8.4e-06 26.2 11.3 2.7 2 0 0 2 2 2 2 Chitin recognition protein HC2 PF07382.11 EGF79548.1 - 7.2e-05 23.0 19.4 0.00012 22.2 19.4 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 NTP_transf_9 PF04248.12 EGF79548.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Chitin_bind_1 PF00187.19 EGF79549.1 - 1.2e-48 163.2 110.8 7.2e-10 39.2 16.5 5.4 5 0 0 5 5 5 5 Chitin recognition protein Tyrosinase PF00264.20 EGF79549.1 - 2.3e-41 142.5 0.9 3.9e-41 141.8 0.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase CLTH PF10607.9 EGF79550.1 - 1.4e-32 112.7 0.1 3.4e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGF79550.1 - 7.9e-08 32.2 1.2 1.5e-07 31.3 1.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGF79550.1 - 1.9e-05 24.7 1.3 4.4e-05 23.5 1.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGF79550.1 - 0.00021 21.2 1.6 0.00037 20.4 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGF79550.1 - 0.00067 19.9 2.2 0.0012 19.1 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGF79550.1 - 0.011 15.6 2.9 0.021 14.7 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF79550.1 - 0.018 14.9 1.2 0.032 14.1 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF79550.1 - 0.028 14.3 1.3 0.051 13.4 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TBCA PF02970.16 EGF79550.1 - 0.031 14.6 3.1 1 9.7 0.6 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A zf-C3HC4_2 PF13923.6 EGF79550.1 - 0.032 14.1 3.5 0.067 13.0 3.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EGF79550.1 - 0.19 11.5 0.9 0.39 10.5 0.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Jnk-SapK_ap_N PF09744.9 EGF79550.1 - 2 8.6 6.5 4.2 7.6 6.5 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Cyclin_N PF00134.23 EGF79551.1 - 7.9e-08 32.1 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF79551.1 - 0.055 13.5 0.5 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain LRR_8 PF13855.6 EGF79552.1 - 1.3e-31 108.1 31.6 1.4e-12 47.2 3.6 5.6 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EGF79552.1 - 2e-25 88.4 32.9 5e-07 30.0 0.9 6.4 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF79552.1 - 4e-11 41.9 34.9 0.031 14.8 0.2 10.1 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 EGF79552.1 - 2.4e-07 30.4 6.8 0.00067 19.2 1.2 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_5 PF13306.6 EGF79552.1 - 0.00033 20.6 6.0 0.00033 20.6 6.0 2.8 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) DUF3557 PF12078.8 EGF79552.1 - 0.00091 19.2 6.2 0.086 12.8 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3557) LRR_6 PF13516.6 EGF79552.1 - 0.026 14.6 35.8 0.2 11.8 0.3 8.2 9 0 0 9 9 9 0 Leucine Rich repeat Fil_haemagg_2 PF13332.6 EGF79554.1 - 0.089 12.9 3.6 0.74 9.9 0.2 2.6 2 0 0 2 2 2 0 Hemagglutinin repeat SlyX PF04102.12 EGF79554.1 - 0.18 12.4 6.5 23 5.7 1.0 4.4 3 1 1 4 4 4 0 SlyX ZapB PF06005.12 EGF79554.1 - 0.23 11.9 8.7 0.31 11.5 4.5 3.3 4 0 0 4 4 4 0 Cell division protein ZapB TolA_bind_tri PF16331.5 EGF79554.1 - 1.1 9.4 7.2 0.77 9.9 4.6 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Cep57_CLD_2 PF14197.6 EGF79554.1 - 8.6 6.5 10.1 28 4.9 3.5 3.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CC2D2AN-C2 PF15625.6 EGF79555.1 - 3.2e-18 66.1 0.0 2.7e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 CC2D2A N-terminal C2 domain DUF5523 PF17661.1 EGF79555.1 - 3.5e-08 33.4 1.8 3.5e-08 33.4 1.8 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5523) C2 PF00168.30 EGF79555.1 - 5.9e-08 32.9 0.0 3.1e-06 27.4 0.0 2.7 2 1 0 2 2 2 1 C2 domain Ctf8 PF09696.10 EGF79556.1 - 2.1e-09 37.8 0.1 1.8e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 Ctf8 zf-C2H2 PF00096.26 EGF79557.1 - 1.1e-11 44.6 10.2 6.4e-06 26.3 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF79557.1 - 2.8e-09 37.0 7.2 0.00018 22.0 1.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF79557.1 - 1.9e-08 34.3 0.4 1.9e-08 34.3 0.4 2.6 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGF79557.1 - 2.1e-05 24.7 2.6 0.091 13.1 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF79557.1 - 2.2e-05 24.7 3.1 0.027 14.9 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EGF79557.1 - 0.00051 20.4 1.8 0.48 10.9 0.1 2.3 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 EGF79557.1 - 0.0015 18.4 3.1 0.021 14.8 0.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EGF79557.1 - 0.0018 18.4 3.2 0.03 14.5 0.6 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zf-C2H2_11 PF16622.5 EGF79557.1 - 0.005 16.6 3.1 1.3 8.8 0.8 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_ZIC PF18366.1 EGF79557.1 - 0.026 14.6 1.5 5.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain CD24 PF14984.6 EGF79557.1 - 0.03 14.5 4.7 0.041 14.1 4.7 1.2 1 0 0 1 1 1 0 CD24 protein zf-H2C2_5 PF13909.6 EGF79557.1 - 0.045 13.5 10.9 0.15 11.8 3.8 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain C5HCH PF17982.1 EGF79557.1 - 0.063 13.4 0.6 0.063 13.4 0.6 2.5 2 1 0 2 2 2 0 NSD Cys-His rich domain zf_UBZ PF18439.1 EGF79557.1 - 0.12 12.0 2.1 0.45 10.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2757 PF10955.8 EGF79557.1 - 0.17 12.2 1.0 4.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) zf-C2H2_8 PF15909.5 EGF79557.1 - 0.45 10.8 5.7 0.25 11.7 3.1 1.8 1 1 1 2 2 2 0 C2H2-type zinc ribbon Laminin_EGF PF00053.24 EGF79557.1 - 2.2 8.5 6.5 8.8 6.6 0.8 2.7 2 1 1 3 3 3 0 Laminin EGF domain FYVE PF01363.21 EGF79557.1 - 2.6 8.3 10.0 0.5 10.5 2.5 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.16 EGF79557.1 - 5.5 7.2 12.2 24 5.2 4.5 3.1 1 1 2 3 3 3 0 AN1-like Zinc finger MitMem_reg PF13012.6 EGF79558.1 - 1.3e-22 80.3 1.0 2.3e-22 79.5 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGF79558.1 - 8.5e-20 70.9 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PD-C2-AF1 PF09310.10 EGF79558.1 - 0.061 12.7 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 POU domain, class 2, associating factor 1 RNA_pol_Rpb2_6 PF00562.28 EGF79559.1 - 7.9e-122 407.1 0.1 1.1e-121 406.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EGF79559.1 - 1.4e-36 124.8 0.8 4.5e-35 119.9 0.2 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 EGF79559.1 - 2.4e-22 79.3 0.1 7e-22 77.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EGF79559.1 - 2.8e-22 78.8 0.8 5.6e-21 74.6 0.4 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGF79559.1 - 5.1e-21 74.6 0.3 7.4e-11 42.1 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 3 Intein_splicing PF14890.6 EGF79559.1 - 8.3e-10 38.7 0.0 1.8e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Intein splicing domain RNA_pol_Rpb2_1 PF04563.15 EGF79559.1 - 3.2e-07 30.1 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGF79559.1 - 3.3e-06 26.9 2.3 4.5e-06 26.4 1.5 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 MRNIP PF15749.5 EGF79559.1 - 0.013 16.2 1.0 0.03 15.1 1.0 1.6 1 0 0 1 1 1 0 MRN-interacting protein Zn_Tnp_IS1595 PF12760.7 EGF79559.1 - 0.021 14.8 0.3 0.047 13.7 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EGF79559.1 - 0.16 11.9 0.9 0.48 10.3 0.9 1.8 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit RNA_pol_Rpb2_1 PF04563.15 EGF79560.1 - 2.1e-09 37.2 0.2 2.3e-09 37.0 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase beta subunit ATG11 PF10377.9 EGF79562.1 - 2.6e-17 63.1 1.7 6.6e-17 61.8 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 EGF79562.1 - 0.00073 18.8 1.5 0.00073 18.8 1.5 5.7 3 2 2 5 5 5 2 Autophagy protein Apg17 ATG16 PF08614.11 EGF79562.1 - 0.001 19.4 19.3 0.001 19.4 19.3 4.1 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Sugarporin_N PF11471.8 EGF79562.1 - 0.52 10.3 8.4 1.4 8.9 0.9 3.9 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension HU-CCDC81_bac_2 PF18175.1 EGF79562.1 - 1.3 9.0 6.5 0.5 10.3 0.1 3.4 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Filament PF00038.21 EGF79562.1 - 5 6.6 60.8 0.99 8.9 0.3 4.1 2 1 1 3 3 3 0 Intermediate filament protein WD40 PF00400.32 EGF79563.1 - 3.4e-19 68.8 16.2 0.013 16.4 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79563.1 - 1.8e-07 31.3 4.6 0.0012 19.1 0.1 4.6 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF79563.1 - 1.7e-05 23.9 0.8 7.7 5.4 0.1 4.1 2 2 0 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Seipin PF06775.14 EGF79564.1 - 1.7e-34 119.7 1.5 3.7e-34 118.6 1.5 1.5 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) CBM_21 PF03370.13 EGF79565.1 - 3.7e-19 69.0 0.3 7.3e-19 68.0 0.3 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EGF79565.1 - 8.6e-08 32.7 2.1 3e-07 30.9 0.2 2.4 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) p25-alpha PF05517.12 EGF79566.1 - 6.8e-49 166.0 3.8 3.5e-41 141.0 0.1 2.2 2 0 0 2 2 2 2 p25-alpha Suc_Fer-like PF06999.12 EGF79567.1 - 4.6e-48 163.7 0.0 5.6e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FH2 PF02181.23 EGF79568.1 - 1.4e-84 284.4 20.7 3.8e-84 282.9 14.8 3.1 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGF79568.1 - 1.6e-35 122.4 0.9 5.1e-35 120.7 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGF79568.1 - 3.8e-33 114.7 0.4 3.8e-33 114.7 0.4 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF5470 PF17564.2 EGF79568.1 - 0.25 11.6 1.8 0.93 9.7 1.8 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5470) DUF4771 PF15995.5 EGF79568.1 - 0.62 10.3 6.0 0.11 12.8 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4771) JmjC PF02373.22 EGF79570.1 - 3.3e-18 66.2 0.0 7.8e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGF79570.1 - 9.8e-16 58.2 0.0 3.1e-14 53.3 0.0 2.6 1 1 1 2 2 2 1 Cupin-like domain EST1 PF10374.9 EGF79570.1 - 0.0076 16.9 3.8 0.017 15.8 3.8 1.5 1 0 0 1 1 1 1 Telomerase activating protein Est1 HD_4 PF13328.6 EGF79570.1 - 0.12 12.1 0.4 0.2 11.4 0.4 1.3 1 0 0 1 1 1 0 HD domain Presenilin PF01080.17 EGF79570.1 - 6.1 5.5 4.9 9.4 4.9 4.9 1.2 1 0 0 1 1 1 0 Presenilin Anoctamin PF04547.12 EGF79571.1 - 1.1e-114 383.8 15.5 1.4e-114 383.4 15.5 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EGF79571.1 - 2.3e-16 60.2 0.0 3.8e-15 56.2 0.0 2.7 2 1 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RcpB PF16971.5 EGF79571.1 - 0.15 11.9 2.1 16 5.3 0.0 2.8 2 0 0 2 2 2 0 Rough colony protein B, tight adherence - tad - subunit DUF1279 PF06916.13 EGF79572.1 - 3.5e-11 43.5 0.5 8.9e-11 42.2 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) FHA PF00498.26 EGF79574.1 - 1.6e-13 50.8 0.0 3.9e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EGF79574.1 - 4.9e-12 45.4 9.9 1e-11 44.4 9.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGF79574.1 - 3.5e-08 33.7 12.2 5.6e-08 33.0 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EGF79574.1 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 EGF79574.1 - 0.0044 16.9 12.6 0.0073 16.2 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF79574.1 - 0.012 15.7 4.8 0.022 14.8 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGF79574.1 - 0.012 15.9 8.5 0.031 14.6 8.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF79574.1 - 0.013 15.3 13.0 0.022 14.6 13.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF79574.1 - 0.032 14.2 10.9 0.054 13.5 10.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF79574.1 - 0.29 11.2 10.1 0.38 10.8 7.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.29 EGF79574.1 - 3.1 7.8 9.1 5.5 7.0 9.1 1.4 1 0 0 1 1 1 0 PHD-finger ABC2_membrane PF01061.24 EGF79575.1 - 4.1e-32 111.3 20.6 4.1e-32 111.3 20.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGF79575.1 - 1.9e-23 83.5 0.0 2.8e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF79575.1 - 8.1e-05 22.6 1.8 0.027 14.3 0.2 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF79575.1 - 0.013 15.2 0.4 0.03 14.1 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EGF79575.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Dynamin_N PF00350.23 EGF79575.1 - 0.072 13.1 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Dynamin family PDR_CDR PF06422.12 EGF79575.1 - 0.099 12.6 2.0 2.4 8.1 0.1 2.9 3 0 0 3 3 3 0 CDR ABC transporter RsgA_GTPase PF03193.16 EGF79575.1 - 0.15 12.0 0.3 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EGF79575.1 - 0.2 11.0 0.2 2 7.8 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ferlin_C PF16165.5 EGF79575.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.3 3 0 0 3 3 3 0 Ferlin C-terminus eIF2_C PF09173.11 EGF79577.1 - 1.2e-36 124.8 0.3 3e-36 123.5 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGF79577.1 - 9.2e-24 84.0 0.6 5.1e-23 81.6 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGF79577.1 - 8e-13 48.6 0.4 2.2e-12 47.2 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF79577.1 - 0.0033 17.5 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF79577.1 - 0.0041 17.0 0.3 0.052 13.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGF79577.1 - 0.0086 16.1 0.2 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Tax PF02959.16 EGF79577.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 HTLV Tax Dynamin_N PF00350.23 EGF79577.1 - 0.065 13.3 0.4 0.26 11.3 0.4 2.2 1 1 0 1 1 1 0 Dynamin family SH3_1 PF00018.28 EGF79578.1 - 0.00081 19.0 0.0 0.0066 16.0 0.0 2.3 2 0 0 2 2 2 1 SH3 domain EphA2_TM PF14575.6 EGF79579.1 - 0.89 10.5 0.0 0.89 10.5 0.0 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sec7 PF01369.20 EGF79580.1 - 4.4e-26 91.7 0.0 8e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGF79580.1 - 7.4e-13 48.9 0.0 3.9e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 EGF79580.1 - 0.0082 16.6 0.0 0.34 11.4 0.0 2.7 2 0 0 2 2 2 1 PH domain ubiquitin PF00240.23 EGF79581.1 - 1.7e-13 50.1 0.0 2.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF5571 PF17732.1 EGF79581.1 - 0.0081 15.7 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5571) Rad60-SLD PF11976.8 EGF79581.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L22 PF00237.19 EGF79582.1 - 6.7e-21 74.5 0.7 1.3e-20 73.6 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Mob1_phocein PF03637.17 EGF79583.1 - 7.6e-81 270.1 0.2 9.1e-81 269.9 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family PDEase_I PF00233.19 EGF79584.1 - 7.8e-70 235.3 0.5 9.3e-70 235.0 0.5 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Transport_MerF PF11431.8 EGF79584.1 - 0.19 11.6 0.1 0.36 10.8 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein MerF HVSL PF09749.9 EGF79585.1 - 3e-46 157.8 0.1 3.6e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein IML1 PF12257.8 EGF79586.1 - 2.2e-116 388.0 0.0 3.7e-116 387.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGF79586.1 - 8.6e-20 70.6 0.2 1.8e-19 69.5 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) OGG_N PF07934.12 EGF79588.1 - 7e-20 71.3 0.1 1.2e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGF79588.1 - 2.6e-14 53.6 0.0 3.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGF79588.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif ArfGap PF01412.18 EGF79589.1 - 4.4e-40 136.4 1.7 4.4e-40 136.4 1.7 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF3973 PF13119.6 EGF79589.1 - 0.13 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) TFIIA PF03153.13 EGF79589.1 - 1.6 8.7 15.5 2.2 8.2 15.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PQQ_3 PF13570.6 EGF79590.1 - 1.5e-24 85.7 0.1 0.00012 22.5 0.1 6.8 8 0 0 8 8 8 5 PQQ-like domain PQQ PF01011.21 EGF79590.1 - 3.3e-13 48.9 0.4 0.016 15.1 0.0 5.9 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_2 PF13360.6 EGF79590.1 - 6.2e-12 45.6 0.0 3.7e-05 23.4 0.0 3.3 1 1 2 3 3 3 3 PQQ-like domain AMP-binding PF00501.28 EGF79591.1 - 1.6e-33 115.9 0.0 4.3e-33 114.5 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF79591.1 - 7.6e-06 26.8 0.1 1.8e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBFB_NFYA PF02045.15 EGF79593.1 - 2.2e-27 95.4 5.1 3.9e-27 94.6 5.1 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ACC_epsilon PF13822.6 EGF79593.1 - 0.015 16.0 0.6 0.015 16.0 0.6 3.3 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit DEC-1_N PF04625.13 EGF79593.1 - 0.86 8.6 6.6 0.056 12.5 1.8 1.4 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region SIS PF01380.22 EGF79594.1 - 1.9e-61 205.7 0.2 3.2e-34 117.6 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGF79594.1 - 1.7e-15 57.4 0.0 4.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGF79594.1 - 2.9e-11 43.4 0.0 8.6e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGF79594.1 - 0.0027 16.6 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GFD1 PF17331.2 EGF79594.1 - 0.0064 16.6 0.7 0.017 15.3 0.7 1.7 1 0 0 1 1 1 1 GFD1 mRNA transport factor SIS_2 PF13580.6 EGF79594.1 - 0.055 13.5 0.0 0.19 11.7 0.0 1.9 1 1 1 2 2 2 0 SIS domain DUF2529 PF10740.9 EGF79594.1 - 0.058 13.0 0.1 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2529) Na_Ca_ex PF01699.24 EGF79595.1 - 4.6e-40 137.0 40.7 3.7e-24 85.4 16.9 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF5357 PF17310.2 EGF79595.1 - 1.5 7.3 5.0 0.14 10.7 0.3 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5357) Acyl-CoA_dh_1 PF00441.24 EGF79596.1 - 2.6e-30 105.6 2.3 3.8e-30 105.1 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF79596.1 - 6e-22 77.7 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGF79596.1 - 1.1e-13 51.8 0.0 2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF79596.1 - 7.1e-13 49.0 3.6 1.3e-12 48.2 3.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGF79596.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Skp1 PF01466.19 EGF79598.1 - 1e-29 102.3 1.0 1e-29 102.3 1.0 2.0 3 0 0 3 3 3 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGF79598.1 - 1.6e-24 85.8 0.5 5.4e-24 84.1 0.0 2.1 2 1 1 3 3 3 1 Skp1 family, tetramerisation domain PAP_assoc PF03828.19 EGF79599.1 - 5.7e-05 23.2 0.0 0.00018 21.6 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGF79599.1 - 0.00036 20.8 0.0 0.00076 19.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGF79599.1 - 0.00082 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF2278 PF10042.9 EGF79599.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) TSC22 PF01166.18 EGF79600.1 - 0.05 13.9 0.9 0.17 12.2 0.9 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family Takusan PF04822.13 EGF79600.1 - 0.17 11.8 3.8 0.53 10.2 3.8 1.9 1 0 0 1 1 1 0 Takusan HMG_box PF00505.19 EGF79601.1 - 2.9e-25 88.5 0.1 4e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF79601.1 - 1.9e-17 63.6 0.1 2.6e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 EGF79601.1 - 6.7e-06 26.0 0.3 2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CHDNT PF08073.12 EGF79601.1 - 0.00022 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 EGF79601.1 - 0.048 14.2 0.2 0.074 13.6 0.2 1.3 1 0 0 1 1 1 0 YABBY protein Homeodomain PF00046.29 EGF79602.1 - 8.4e-16 57.6 0.0 9.3e-16 57.4 0.0 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGF79602.1 - 0.0084 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain zf-C3HC4 PF00097.25 EGF79603.1 - 3.1e-08 33.4 6.2 7e-08 32.2 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF79603.1 - 1.7e-07 31.0 7.4 1e-06 28.5 6.7 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF79603.1 - 1.1e-06 28.5 2.6 1.1e-06 28.5 2.6 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF79603.1 - 1.1e-06 28.3 5.6 2.3e-06 27.3 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF79603.1 - 9.5e-06 25.9 9.0 9.5e-06 25.9 9.0 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 EGF79603.1 - 1.7e-05 24.7 6.4 1.8e-05 24.6 4.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGF79603.1 - 6.5e-05 23.0 7.2 6.5e-05 23.0 7.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGF79603.1 - 0.0029 17.4 6.6 0.011 15.5 6.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGF79603.1 - 0.28 11.3 3.6 0.63 10.2 3.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ACC PF17848.1 EGF79603.1 - 0.46 10.6 2.7 0.81 9.8 0.7 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-RING_6 PF14835.6 EGF79603.1 - 1.2 9.0 5.3 3.3 7.7 5.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EGF79603.1 - 1.9 8.9 9.3 12 6.3 9.4 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGF79603.1 - 3 7.7 6.5 4.8 7.0 3.8 2.5 2 1 0 2 2 2 0 RING-like zinc finger TP6A_N PF04406.14 EGF79605.1 - 4.9e-18 64.9 0.6 9.3e-18 64.0 0.6 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SWIB PF02201.18 EGF79606.1 - 4.7e-50 167.4 3.5 6.5e-25 86.8 0.5 2.7 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.11 EGF79606.1 - 2.2e-09 37.1 0.3 7.6e-09 35.4 0.3 1.9 1 0 0 1 1 1 1 DEK C terminal domain IFT57 PF10498.9 EGF79606.1 - 0.01 14.8 7.3 0.018 14.0 7.3 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MMU163 PF17119.5 EGF79606.1 - 0.066 12.4 1.1 0.11 11.6 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Apc15p PF05841.11 EGF79607.1 - 0.035 14.9 0.0 0.066 14.0 0.0 1.5 1 0 0 1 1 1 0 Apc15p protein AA_permease_2 PF13520.6 EGF79608.1 - 3.2e-61 207.5 45.5 3.8e-61 207.2 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF79608.1 - 9.8e-30 103.6 39.4 1.3e-29 103.1 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Terminase_4 PF05119.12 EGF79609.1 - 0.034 14.6 1.9 0.08 13.4 1.9 1.6 1 0 0 1 1 1 0 Phage terminase, small subunit Ribonuclease_3 PF00636.26 EGF79610.1 - 3.5e-19 69.4 0.2 1.3e-18 67.6 0.0 2.0 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF79610.1 - 4.8e-11 42.9 0.0 6.3e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like DUF4600 PF15372.6 EGF79611.1 - 0.012 16.1 2.9 0.15 12.5 2.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Sporozoite_P67 PF05642.11 EGF79611.1 - 0.029 12.5 7.6 0.16 10.1 0.2 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen S-antigen PF05756.11 EGF79611.1 - 0.15 12.4 1.2 0.36 11.2 1.2 1.7 1 0 0 1 1 1 0 S-antigen protein Presenilin PF01080.17 EGF79611.1 - 0.32 9.7 6.1 0.054 12.3 2.1 1.6 2 0 0 2 2 2 0 Presenilin Gemini_V2 PF01524.17 EGF79617.1 - 0.082 13.1 0.6 0.16 12.2 0.6 1.5 1 0 0 1 1 1 0 Geminivirus V2 protein Bcl-2_BAD PF10514.9 EGF79617.1 - 1.4 9.4 9.3 1 9.8 3.5 2.4 2 1 1 3 3 3 0 Pro-apoptotic Bcl-2 protein, BAD CBM_21 PF03370.13 EGF79619.1 - 5.4e-19 68.4 0.0 3.8e-18 65.7 0.0 2.2 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EGF79619.1 - 1.7e-08 34.9 0.0 0.00021 21.8 0.0 2.5 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) MoCF_biosynth PF00994.24 EGF79620.1 - 1.4e-40 138.3 0.3 8.3e-23 80.7 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGF79620.1 - 4.5e-35 120.7 0.1 6.9e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGF79620.1 - 5.8e-12 45.6 0.0 2.3e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 MoeA C-terminal region (domain IV) Pox_F12L PF03337.13 EGF79620.1 - 0.042 12.0 0.1 0.059 11.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein AICARFT_IMPCHas PF01808.18 EGF79622.1 - 2.6e-89 299.6 0.0 3.6e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGF79622.1 - 3.4e-23 81.6 0.0 9.4e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain WD40 PF00400.32 EGF79623.1 - 1.5e-41 139.6 18.6 4.5e-08 33.6 0.4 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79623.1 - 1.5e-14 54.1 0.0 0.0045 17.2 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EGF79623.1 - 3.8e-12 46.3 2.1 7.8e-12 45.3 2.1 1.6 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.8 EGF79623.1 - 7.9e-05 21.5 0.4 0.016 13.9 0.0 2.9 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF79623.1 - 0.0017 17.4 0.1 24 3.8 0.0 4.6 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGF79623.1 - 0.0031 17.4 0.1 40 4.3 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGF79623.1 - 0.028 12.9 0.0 0.096 11.2 0.0 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain Lactonase PF10282.9 EGF79623.1 - 0.062 12.5 0.0 5.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller MMS1_N PF10433.9 EGF79623.1 - 0.12 11.0 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Proteasome_A_N PF10584.9 EGF79623.1 - 1.5 8.6 6.4 6.5 6.5 0.1 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DEFB136 PF17333.2 EGF79624.1 - 0.15 12.1 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Beta defensin 136 LRR_6 PF13516.6 EGF79624.1 - 0.23 11.6 4.2 3.9 7.8 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat TPK_catalytic PF04263.16 EGF79625.1 - 2.9e-38 130.6 0.0 5.7e-38 129.7 0.0 1.5 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGF79625.1 - 8.4e-08 31.8 0.1 5.3e-07 29.3 0.1 2.3 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Proteasome PF00227.26 EGF79626.1 - 3.3e-27 95.2 0.1 3.9e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit ABC_tran PF00005.27 EGF79627.1 - 7.7e-32 110.7 0.2 1.1e-15 58.4 0.0 3.1 2 1 0 2 2 2 2 ABC transporter Cyt-b5 PF00173.28 EGF79627.1 - 2.8e-18 65.8 0.0 6.9e-17 61.4 0.0 2.5 3 0 0 3 3 2 1 Cytochrome b5-like Heme/Steroid binding domain SMC_N PF02463.19 EGF79627.1 - 3.7e-11 42.9 5.9 0.0013 18.2 0.9 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF79627.1 - 1.5e-10 41.4 7.3 0.0067 16.3 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EGF79627.1 - 1.3e-05 25.2 0.0 0.044 13.7 0.0 3.1 3 0 0 3 3 3 2 Rad17 P-loop domain AAA PF00004.29 EGF79627.1 - 1.4e-05 25.5 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGF79627.1 - 4.3e-05 23.5 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase SRP54 PF00448.22 EGF79627.1 - 0.00028 20.6 0.9 0.083 12.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 EGF79627.1 - 0.00028 20.8 0.7 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EGF79627.1 - 0.00075 20.0 0.1 0.27 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGF79627.1 - 0.00082 19.2 8.5 1.1 8.9 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain Thymidylate_kin PF02223.17 EGF79627.1 - 0.001 18.8 0.2 0.56 9.9 0.0 2.8 3 0 0 3 3 2 1 Thymidylate kinase AAA_16 PF13191.6 EGF79627.1 - 0.0012 19.3 0.0 0.41 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGF79627.1 - 0.0015 18.3 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF79627.1 - 0.0017 18.5 0.1 1 9.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGF79627.1 - 0.0019 18.5 0.1 2.3 8.6 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 EGF79627.1 - 0.002 17.9 1.8 0.41 10.3 0.0 2.9 2 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGF79627.1 - 0.003 17.8 0.0 0.9 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGF79627.1 - 0.0035 17.9 6.5 0.016 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGF79627.1 - 0.0035 17.1 0.7 1.1 9.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGF79627.1 - 0.0042 17.4 0.0 0.76 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGF79627.1 - 0.0078 16.2 0.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EGF79627.1 - 0.019 14.9 0.2 1.8 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGF79627.1 - 0.022 14.8 0.5 6.2 6.9 0.0 3.2 2 1 1 3 3 3 0 AAA domain SbcCD_C PF13558.6 EGF79627.1 - 0.025 14.8 0.0 10 6.5 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EGF79627.1 - 0.059 12.6 0.1 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.11 EGF79627.1 - 0.078 12.7 0.0 3.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Mg_chelatase PF01078.21 EGF79627.1 - 0.081 12.3 0.1 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EGF79627.1 - 0.16 12.1 1.4 12 6.0 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.14 EGF79627.1 - 0.23 11.4 0.5 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 EGF79627.1 - 0.42 10.5 1.4 17 5.3 0.0 2.7 2 0 0 2 2 2 0 NTPase PDEase_I PF00233.19 EGF79629.1 - 1.3e-69 234.6 4.1 1.8e-69 234.1 4.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EGF79629.1 - 1.9e-10 41.4 0.0 3.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.6 EGF79630.1 - 0.00033 20.9 0.3 0.031 14.6 0.0 3.9 4 1 1 5 5 5 2 Tetratricopeptide repeat RhoGAP PF00620.27 EGF79630.1 - 0.079 12.8 1.4 5.7 6.7 0.2 2.4 2 0 0 2 2 2 0 RhoGAP domain TPR_14 PF13428.6 EGF79630.1 - 0.11 13.4 2.4 37 5.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 EGF79631.1 - 5.2e-12 45.4 0.0 8.5e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.22 EGF79632.1 - 2.1e-22 79.7 0.7 1.2e-19 70.8 0.2 2.7 3 0 0 3 3 3 2 Fasciclin domain Dynamin_M PF01031.20 EGF79633.1 - 3.3e-35 121.7 0.1 4.6e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 EGF79633.1 - 3.8e-24 85.6 0.3 3.7e-23 82.4 0.3 2.3 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 EGF79633.1 - 4.7e-10 39.5 0.1 3.4e-09 36.7 0.0 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGF79633.1 - 6.7e-05 22.9 0.6 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Septin PF00735.18 EGF79633.1 - 0.0024 17.2 0.2 1.1 8.5 0.1 2.3 2 0 0 2 2 2 2 Septin AAA_23 PF13476.6 EGF79633.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF79633.1 - 0.08 13.3 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EGF79633.1 - 0.17 11.4 0.5 2.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Glyco_trans_2_3 PF13632.6 EGF79634.1 - 2e-19 70.3 1.3 2e-19 70.3 1.3 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF79634.1 - 1.1e-05 25.5 0.3 2.6e-05 24.2 0.3 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGF79634.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Nup88 PF10168.9 EGF79635.1 - 1.5e-33 115.6 3.2 1e-16 60.0 1.2 2.2 2 0 0 2 2 2 2 Nuclear pore component Snapin_Pallidin PF14712.6 EGF79635.1 - 1.3 9.4 8.8 3 8.3 1.5 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.12 EGF79635.1 - 4.7 7.3 6.5 1.9 8.6 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EGF79635.1 - 9.6 6.3 7.4 0.92 9.6 1.9 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 RRM_1 PF00076.22 EGF79636.1 - 3.4e-44 148.5 0.1 3.5e-21 74.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF79636.1 - 3.9e-08 33.3 0.0 0.015 15.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EGF79636.1 - 2.1e-06 27.5 0.0 0.0033 17.2 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EGF79636.1 - 0.0069 16.0 0.0 0.066 12.8 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 EGF79636.1 - 0.033 13.6 56.7 0.056 12.8 56.7 1.3 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 EGF79636.1 - 7.8 5.5 31.5 11 5.0 31.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PBP_N PF17093.5 EGF79636.1 - 7.9 6.7 9.9 0.59 10.4 3.4 2.3 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus Ribosomal_L1 PF00687.21 EGF79637.1 - 1.1e-26 93.9 0.1 1.4e-26 93.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AF-4 PF05110.13 EGF79639.1 - 0.00039 18.7 27.8 0.00039 18.7 27.8 2.1 2 0 0 2 2 2 1 AF-4 proto-oncoprotein Pyr_redox_2 PF07992.14 EGF79641.1 - 5.2e-49 167.1 0.0 8.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF79641.1 - 1.3e-11 44.9 0.6 2.9e-10 40.5 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGF79641.1 - 4.2e-05 23.3 0.1 0.11 12.1 0.0 3.0 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGF79641.1 - 0.00031 20.1 0.4 0.0018 17.6 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGF79641.1 - 0.018 15.0 0.0 0.33 10.9 0.0 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EGF79641.1 - 0.039 12.7 1.0 0.17 10.6 0.0 2.2 2 1 1 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 EGF79641.1 - 0.061 13.8 1.0 4.9 7.6 0.0 3.3 3 1 0 3 3 3 0 Putative NAD(P)-binding Thioredoxin PF00085.20 EGF79642.1 - 2e-21 75.9 0.0 2.3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGF79642.1 - 7.5e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGF79642.1 - 2.6e-05 24.6 0.0 0.00044 20.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGF79642.1 - 5.9e-05 22.8 0.0 6.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGF79642.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGF79642.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family AF-4 PF05110.13 EGF79643.1 - 1.7 6.6 9.2 1.8 6.5 9.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 EGF79644.1 - 1e-16 61.0 7.0 0.0018 19.1 0.0 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79644.1 - 2.6e-07 30.9 0.0 0.00076 19.7 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF79644.1 - 0.028 14.3 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A R2K_3 PF14243.6 EGF79644.1 - 0.036 14.1 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Asp PF00026.23 EGF79645.1 - 1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79645.1 - 7.6e-06 25.8 0.0 2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PTS_2-RNA PF01885.16 EGF79646.1 - 7.6e-65 218.4 1.7 8.7e-65 218.2 1.7 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF5361 PF17318.2 EGF79646.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5361) DUF1075 PF06388.11 EGF79647.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) Wzy_C PF04932.15 EGF79647.1 - 0.073 12.7 0.6 0.13 11.9 0.5 1.4 1 1 0 1 1 1 0 O-Antigen ligase GRIM-19 PF06212.12 EGF79648.1 - 4e-22 78.6 0.1 3.8e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 GRIM-19 protein VWA_2 PF13519.6 EGF79649.1 - 4.7e-10 40.1 0.0 3.5e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain LRR_4 PF12799.7 EGF79650.1 - 0.021 15.3 15.1 0.53 10.8 0.4 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGF79650.1 - 0.24 11.5 11.9 1.7 8.9 0.1 6.4 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 EGF79650.1 - 1.7 9.5 5.4 22 6.1 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat Sds3 PF08598.11 EGF79651.1 - 5.7e-22 78.8 7.6 5.7e-22 78.8 7.6 2.7 2 1 0 2 2 2 1 Sds3-like 2Fe-2S_thioredx PF01257.19 EGF79652.1 - 6.7e-61 204.4 0.3 8.4e-61 204.1 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bac_GH3_C PF18034.1 EGF79652.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain PRMT5 PF05185.16 EGF79653.1 - 3.3e-67 225.6 0.0 4.5e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGF79653.1 - 6.9e-52 175.9 1.9 1e-51 175.3 1.9 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 EGF79653.1 - 3.4e-45 154.3 0.0 4.7e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Methyltransf_25 PF13649.6 EGF79653.1 - 0.0053 17.4 0.0 0.0096 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF1730 PF08331.10 EGF79653.1 - 0.13 12.2 0.0 26 4.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) DUF1638 PF07796.11 EGF79654.1 - 0.0064 16.6 0.1 0.0066 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1638) CHCH PF06747.13 EGF79654.1 - 0.023 14.8 0.8 0.3 11.3 1.0 2.0 1 1 1 2 2 2 0 CHCH domain UPF0203 PF05254.12 EGF79654.1 - 0.038 14.2 0.4 0.094 13.0 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 EGF79654.1 - 0.056 13.5 0.9 7.4 6.7 0.5 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EGF79654.1 - 0.087 12.9 0.8 3.3 7.8 0.1 2.1 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PI_PP_I PF18363.1 EGF79655.1 - 0.086 13.0 3.1 0.13 12.5 1.0 2.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF3644 PF12358.8 EGF79657.1 - 3.9 8.0 7.5 0.72 10.4 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) IQ PF00612.27 EGF79657.1 - 7 6.7 8.6 0.37 10.7 0.2 3.2 3 0 0 3 3 3 0 IQ calmodulin-binding motif Sugar_tr PF00083.24 EGF79659.1 - 3.9e-55 187.5 28.2 5e-55 187.2 28.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF79659.1 - 1e-24 87.2 28.9 1.5e-24 86.6 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2518 PF10726.9 EGF79659.1 - 0.051 13.2 1.4 0.18 11.5 1.4 1.9 1 0 0 1 1 1 0 Protein of function (DUF2518) PTPS PF01242.19 EGF79661.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase DUF4423 PF14394.6 EGF79661.1 - 0.12 12.1 0.7 0.22 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Headcase PF16002.5 EGF79662.1 - 0.038 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Headcase protein Arm-DNA-bind_4 PF14657.6 EGF79662.1 - 0.043 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain Asp PF00026.23 EGF79663.1 - 1.3e-14 54.4 0.1 1.9e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79663.1 - 0.00012 21.9 0.1 0.12 12.2 0.0 2.6 2 1 0 2 2 2 2 Xylanase inhibitor C-terminal AAA_16 PF13191.6 EGF79665.1 - 0.006 17.0 0.0 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EGF79665.1 - 0.02 15.2 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF79665.1 - 0.12 12.6 0.2 0.55 10.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain MFS_4 PF06779.14 EGF79667.1 - 0.042 13.1 0.0 0.045 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB DUF4246 PF14033.6 EGF79668.1 - 1.7e-30 106.6 0.0 2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EGF79668.1 - 0.075 13.4 0.0 4.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase TFR_dimer PF04253.15 EGF79671.1 - 2.5e-32 111.5 0.6 9.4e-32 109.7 0.6 1.8 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGF79671.1 - 5.3e-21 75.2 0.0 9.7e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGF79671.1 - 1e-13 51.1 0.6 4.4e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 PA domain Choline_kinase PF01633.20 EGF79672.1 - 3.8e-57 193.3 0.0 7.1e-57 192.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGF79672.1 - 2.3e-07 31.0 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2205 PF10224.9 EGF79673.1 - 3.6e-11 42.9 0.1 5.8e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Short coiled-coil protein CENP-F_N PF10481.9 EGF79673.1 - 0.013 15.2 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain NDK PF00334.19 EGF79674.1 - 6.5e-147 482.7 0.0 3.5e-38 130.7 0.0 4.4 4 0 0 4 4 4 4 Nucleoside diphosphate kinase Thioredoxin PF00085.20 EGF79674.1 - 5.9e-08 32.6 0.1 1.5e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Amidohydro_2 PF04909.14 EGF79674.1 - 0.15 11.8 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase GCFC PF07842.12 EGF79675.1 - 3.3e-56 190.9 13.2 2.3e-54 184.9 13.2 2.3 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGF79675.1 - 2.9e-14 52.7 1.6 6.7e-14 51.5 1.6 1.7 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EGF79675.1 - 1.4e-06 28.7 7.6 1.4e-06 28.7 7.6 3.1 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EGF79675.1 - 4e-06 26.8 0.7 4e-06 26.8 0.7 3.1 3 0 0 3 3 3 1 G-patch domain FG-GAP PF01839.23 EGF79677.1 - 5.7e-19 67.9 9.8 2.8e-08 33.7 0.6 4.1 4 0 0 4 4 4 3 FG-GAP repeat Zn_dep_PLPC PF00882.18 EGF79677.1 - 1.5e-14 54.4 1.4 2.9e-14 53.5 1.4 1.5 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 EGF79677.1 - 3.8e-06 27.4 13.2 0.0022 18.5 3.1 4.0 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EGF79677.1 - 0.19 11.1 0.4 3.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Malate_synthase PF01274.22 EGF79678.1 - 1.1e-214 713.6 0.0 1.2e-214 713.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase ChaC PF04752.12 EGF79679.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 ChaC-like protein Peptidase_C2 PF00648.21 EGF79680.1 - 4.5e-10 39.0 0.0 2.3e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Calpain family cysteine protease DUF4378 PF14309.6 EGF79680.1 - 0.0018 18.7 0.6 0.015 15.7 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4378) DUF5092 PF17010.5 EGF79680.1 - 1.4 8.8 4.7 0.31 10.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5092) TPR_MLP1_2 PF07926.12 EGF79681.1 - 0.0022 18.0 5.7 0.0022 18.0 5.7 4.4 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 EGF79681.1 - 0.038 14.4 0.3 0.038 14.4 0.3 4.7 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DASH_Dam1 PF08653.10 EGF79681.1 - 1.1 9.1 3.8 34 4.3 0.1 3.5 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF4407 PF14362.6 EGF79681.1 - 2.1 7.6 47.7 1.4 8.2 20.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.10 EGF79681.1 - 2.1 8.7 15.9 15 6.0 0.1 5.2 5 0 0 5 5 5 0 Osmosensory transporter coiled coil MtrG PF04210.13 EGF79681.1 - 3 7.8 5.2 20 5.1 0.1 3.5 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Tweety PF04906.13 EGF79681.1 - 4 6.0 8.5 1.4 7.5 1.9 2.4 1 1 0 2 2 2 0 Tweety CRIM PF16978.5 EGF79682.1 - 5.2e-39 133.6 0.0 3.2e-38 131.1 0.0 2.3 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGF79682.1 - 4.1e-19 68.9 1.9 9.4e-19 67.7 0.7 2.3 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Cobl PF09469.10 EGF79682.1 - 0.00095 19.4 0.1 0.0023 18.1 0.1 1.6 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain RBD PF02196.15 EGF79682.1 - 0.27 11.3 4.8 0.31 11.2 0.1 3.2 4 0 0 4 4 4 0 Raf-like Ras-binding domain Ribosomal_S19 PF00203.21 EGF79683.1 - 0.16 11.8 0.2 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S19 ABC_membrane PF00664.23 EGF79684.1 - 1.7e-75 254.2 29.3 8.4e-39 133.9 10.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF79684.1 - 9e-50 168.7 0.0 1.1e-27 97.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF79684.1 - 3e-11 43.2 2.3 0.00087 18.8 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF79684.1 - 3.9e-06 26.9 0.2 0.099 12.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGF79684.1 - 1.1e-05 25.1 0.3 0.011 15.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGF79684.1 - 5.5e-05 23.6 0.1 0.43 10.9 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGF79684.1 - 0.00017 21.5 0.4 0.089 12.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 EGF79684.1 - 0.0002 21.5 2.7 0.21 11.6 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EGF79684.1 - 0.00077 20.0 0.7 0.2 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGF79684.1 - 0.00088 19.2 4.1 3.6 7.3 0.4 4.2 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EGF79684.1 - 0.0011 18.3 0.0 0.049 12.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 EGF79684.1 - 0.0011 19.0 1.3 0.018 15.1 0.1 2.4 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 EGF79684.1 - 0.0034 16.5 0.1 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EGF79684.1 - 0.0073 15.3 0.3 2.5 6.9 0.0 2.5 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EGF79684.1 - 0.0087 15.8 0.2 2.2 7.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGF79684.1 - 0.011 16.0 1.0 7.9 6.7 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGF79684.1 - 0.011 15.2 0.1 0.86 9.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 EGF79684.1 - 0.039 13.7 0.2 0.3 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 EGF79684.1 - 0.051 12.7 0.2 1.5 7.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Roc PF08477.13 EGF79684.1 - 0.11 12.7 2.7 8.8 6.6 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 EGF79684.1 - 0.13 12.0 0.4 4 7.1 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.22 EGF79684.1 - 0.45 9.7 1.6 14 4.8 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain AIG1 PF04548.16 EGF79684.1 - 0.54 9.5 2.3 6.4 6.0 0.2 2.5 2 0 0 2 2 2 0 AIG1 family Sensor PF13796.6 EGF79684.1 - 0.67 10.0 14.1 0.71 9.9 0.8 4.5 3 2 0 4 4 4 0 Putative sensor TM231 PF10149.9 EGF79685.1 - 3.5e-53 180.9 1.7 2e-51 175.2 1.7 2.0 1 1 0 1 1 1 1 Transmembrane protein 231 DUF468 PF04318.12 EGF79685.1 - 0.063 14.0 0.1 0.16 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF468) His_Phos_1 PF00300.22 EGF79686.1 - 1.2e-34 119.7 0.0 1.2e-30 106.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4207 PF13904.6 EGF79687.1 - 5.1e-06 26.4 26.5 5.1e-06 26.4 26.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) Exonuc_VII_L PF02601.15 EGF79687.1 - 0.22 11.1 12.9 0.27 10.8 12.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PTPA PF03095.15 EGF79687.1 - 0.24 10.8 7.8 0.42 10.0 7.8 1.3 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF2730 PF10805.8 EGF79687.1 - 0.29 11.2 8.8 4.7 7.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Mvb12 PF09452.10 EGF79687.1 - 2.6 8.5 11.3 1.4 9.4 5.6 2.7 1 1 0 2 2 2 0 ESCRT-I subunit Mvb12 DDOST_48kD PF03345.14 EGF79688.1 - 8.5e-129 430.0 1.5 1e-128 429.8 1.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1647 PF07801.11 EGF79688.1 - 0.39 10.5 2.1 4 7.2 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1647) Pkinase PF00069.25 EGF79689.1 - 1.7e-60 204.6 0.1 4.3e-60 203.3 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79689.1 - 1e-38 133.2 0.2 1.9e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF79689.1 - 1.1e-08 34.7 0.0 4.4e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF79689.1 - 0.00069 18.5 0.1 0.0012 17.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF79689.1 - 0.0037 17.2 0.0 0.0081 16.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 EGF79690.1 - 1.8e-34 118.5 0.0 3e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF4239 PF14023.6 EGF79691.1 - 0.0026 17.5 3.8 0.21 11.3 1.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4239) Reprolysin_5 PF13688.6 EGF79691.1 - 0.12 12.6 1.1 0.18 11.9 1.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 putAbiC PF16872.5 EGF79691.1 - 0.17 12.6 1.1 0.31 11.7 0.2 1.8 2 0 0 2 2 2 0 Putative phage abortive infection protein CRR7 PF12095.8 EGF79691.1 - 0.38 11.2 2.9 0.67 10.4 0.9 2.3 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 PQQ_2 PF13360.6 EGF79692.1 - 1e-08 35.1 0.2 8e-08 32.1 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain DUF3471 PF11954.8 EGF79692.1 - 0.031 14.8 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) EMC1_C PF07774.13 EGF79693.1 - 1e-58 198.5 0.2 9.5e-58 195.4 0.1 2.3 2 1 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EGF79693.1 - 0.02 14.5 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain Sec39 PF08314.11 EGF79694.1 - 3.9e-35 121.5 15.6 6e-25 87.9 6.2 2.8 2 1 0 2 2 2 2 Secretory pathway protein Sec39 Metallophos PF00149.28 EGF79695.1 - 4.7e-37 128.5 0.0 6.1e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGF79695.1 - 0.057 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EGF79695.1 - 0.11 12.9 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain AAA_16 PF13191.6 EGF79696.1 - 0.00064 20.1 0.0 0.0022 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PspA_IM30 PF04012.12 EGF79697.1 - 0.0015 18.2 4.8 0.0021 17.7 4.8 1.2 1 0 0 1 1 1 1 PspA/IM30 family Snf7 PF03357.21 EGF79697.1 - 0.0019 17.8 6.6 0.0019 17.8 6.6 1.5 1 1 0 1 1 1 1 Snf7 Snf7 PF03357.21 EGF79698.1 - 1.6e-06 27.9 4.1 2.5e-06 27.2 4.1 1.3 1 0 0 1 1 1 1 Snf7 PTR PF12789.7 EGF79698.1 - 0.16 12.0 0.9 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Phage tail repeat like LuxQ-periplasm PF09308.10 EGF79698.1 - 0.3 10.6 5.8 0.2 11.1 2.8 1.9 1 1 1 2 2 2 0 LuxQ, periplasmic TFIID-31kDa PF02291.15 EGF79699.1 - 1.1e-44 151.4 0.0 1.2e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGF79699.1 - 7.6e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EGF79699.1 - 0.00015 22.1 0.1 0.00022 21.5 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGF79699.1 - 0.00064 19.8 0.0 0.00086 19.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EGF79699.1 - 0.022 15.2 0.2 0.035 14.6 0.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 EGF79699.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Peptidase_M1 PF01433.20 EGF79700.1 - 1e-44 152.7 0.0 1.5e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGF79700.1 - 3.4e-38 130.2 0.1 9e-38 128.8 0.1 1.8 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGF79700.1 - 1.5e-28 100.3 0.3 2.2e-28 99.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Citrate_synt PF00285.21 EGF79702.1 - 1.3e-136 455.4 0.0 1.5e-136 455.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FANCI_HD2 PF14680.6 EGF79704.1 - 8e-24 84.2 1.0 1.5e-23 83.3 1.0 1.4 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S1 PF14675.6 EGF79704.1 - 2.8e-14 53.2 0.2 7.1e-14 51.9 0.2 1.7 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S2 PF14676.6 EGF79704.1 - 1.7e-11 44.7 7.1 7.2e-11 42.7 0.1 4.0 2 1 2 4 4 4 2 FANCI solenoid 2 FANCI_HD1 PF14679.6 EGF79704.1 - 4.3e-05 23.4 0.1 0.00012 22.0 0.1 1.8 1 0 0 1 1 1 1 FANCI helical domain 1 FANCI_S4 PF14678.6 EGF79705.1 - 1.9e-39 135.3 4.3 6.5e-39 133.5 4.3 1.9 1 1 0 1 1 1 1 FANCI solenoid 4 Methyltransf_31 PF13847.6 EGF79706.1 - 9e-12 45.0 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF79706.1 - 3.3e-08 34.1 0.0 5.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF79706.1 - 1e-07 32.6 0.0 3.2e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF79706.1 - 7.1e-06 26.7 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF79706.1 - 0.00012 22.0 0.0 0.00046 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EGF79706.1 - 0.037 13.7 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EGF79706.1 - 0.081 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Macoilin PF09726.9 EGF79707.1 - 0.18 10.3 22.4 0.18 10.3 22.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4603 PF15376.6 EGF79707.1 - 0.37 8.1 30.0 0.45 7.8 30.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SRP-alpha_N PF04086.13 EGF79707.1 - 0.57 10.1 26.1 0.87 9.5 26.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SR-25 PF10500.9 EGF79707.1 - 0.8 9.3 58.0 1.5 8.3 58.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOBP PF15279.6 EGF79707.1 - 5.1 7.6 15.9 6.8 7.2 15.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 EGF79707.1 - 8.9 4.7 20.0 10 4.4 20.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pkinase PF00069.25 EGF79708.1 - 5.1e-71 239.1 0.0 7e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79708.1 - 2.5e-39 135.1 0.0 3.7e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGF79708.1 - 4.5e-37 126.1 2.1 2.2e-20 72.6 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGF79708.1 - 1.1e-09 38.0 0.0 7.7e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGF79708.1 - 0.00038 19.4 1.0 0.00069 18.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Brix PF04427.18 EGF79709.1 - 1.2e-41 143.0 1.1 1.5e-41 142.6 1.1 1.2 1 0 0 1 1 1 1 Brix domain Kinesin PF00225.23 EGF79710.1 - 4.4e-59 200.1 1.9 2.8e-58 197.4 1.9 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF79710.1 - 5.2e-08 33.0 0.0 1.3e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 EGF79710.1 - 0.013 15.6 0.2 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EGF79710.1 - 0.037 14.4 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TMEM223 PF14640.6 EGF79711.1 - 3.1e-43 147.8 0.1 3.7e-43 147.5 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 TcfC PF16967.5 EGF79711.1 - 0.095 12.2 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 E-set like domain Hydantoinase_B PF02538.14 EGF79712.1 - 1.8e-214 713.0 0.6 2.3e-214 712.6 0.6 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EGF79712.1 - 2.8e-97 325.5 0.4 8.4e-97 323.9 0.1 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGF79712.1 - 3.2e-59 199.6 0.0 2e-57 193.7 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region 6PF2K PF01591.18 EGF79713.1 - 2.5e-77 259.2 0.0 4.1e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGF79713.1 - 1.7e-36 125.7 0.0 2.4e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGF79713.1 - 0.0056 16.9 0.7 0.042 14.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain HisKA_2 PF07568.12 EGF79713.1 - 0.064 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase Acyltransferase PF01553.21 EGF79714.1 - 1.5e-18 66.7 0.0 2.5e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGF79714.1 - 1.6e-08 34.5 0.0 1.3e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase C-terminus F-box-like PF12937.7 EGF79715.1 - 0.0019 18.0 3.1 0.0036 17.2 3.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF79715.1 - 0.035 14.0 3.5 0.073 13.0 3.5 1.6 1 0 0 1 1 1 0 F-box domain SAP PF02037.27 EGF79715.1 - 0.048 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 SAP domain FAA_hydrolase PF01557.18 EGF79716.1 - 6.5e-51 173.1 0.0 7.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 EGF79716.1 - 0.0028 17.4 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 KH domain V-SNARE_C PF12352.8 EGF79717.1 - 2.8e-11 43.5 1.6 2.8e-11 43.5 1.6 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGF79717.1 - 3.3e-05 23.7 0.1 0.00011 22.1 0.0 1.9 2 1 0 2 2 2 1 Sec20 DUF745 PF05335.13 EGF79717.1 - 0.095 12.4 1.5 0.21 11.3 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Uds1 PF15456.6 EGF79717.1 - 0.16 12.1 3.1 5.9 7.1 3.1 2.8 1 1 0 1 1 1 0 Up-regulated During Septation Pet100 PF09803.9 EGF79718.1 - 5.8e-11 42.8 3.2 1.8e-10 41.2 3.2 1.7 1 1 0 1 1 1 1 Pet100 DIM1 PF02966.16 EGF79718.1 - 0.058 13.2 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 SH2_2 PF14633.6 EGF79719.1 - 2.2e-67 226.6 1.6 2.2e-67 226.6 1.6 1.9 2 0 0 2 2 1 1 SH2 domain YqgF PF14639.6 EGF79719.1 - 7.1e-29 100.5 0.3 3.9e-28 98.1 0.0 2.4 3 0 0 3 3 3 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EGF79719.1 - 1.4e-27 96.1 0.1 6.4e-27 93.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 EGF79719.1 - 1.6e-17 64.0 1.3 1.5e-16 60.9 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EGF79719.1 - 4.2e-11 43.3 25.9 4.2e-11 43.3 25.9 5.6 3 1 3 6 6 3 1 Acidic N-terminal SPT6 SH2 PF00017.24 EGF79719.1 - 2.4e-08 34.0 0.0 5.9e-07 29.5 0.0 2.8 3 0 0 3 3 2 1 SH2 domain Tex_N PF09371.10 EGF79719.1 - 1.2e-07 31.6 1.4 0.017 14.8 0.0 4.6 5 0 0 5 5 5 2 Tex-like protein N-terminal domain HHH_9 PF17674.1 EGF79719.1 - 9.8e-05 23.2 0.2 9.8e-05 23.2 0.2 3.0 3 0 0 3 3 2 1 HHH domain HHH_3 PF12836.7 EGF79719.1 - 0.00012 22.3 0.1 0.00055 20.1 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.23 EGF79719.1 - 0.0014 18.9 0.0 0.005 17.2 0.0 2.0 2 0 0 2 2 1 1 S1 RNA binding domain Tex_YqgF PF16921.5 EGF79719.1 - 0.0016 18.9 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain SUIM_assoc PF16619.5 EGF79719.1 - 0.2 11.7 9.9 0.086 12.9 6.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EGF79719.1 - 0.45 10.1 7.0 1.1 8.8 7.0 1.6 1 0 0 1 1 1 0 Spt20 family DUF702 PF05142.12 EGF79719.1 - 1.1 9.7 6.6 0.28 11.6 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) IBN_N PF03810.19 EGF79720.1 - 4.4e-13 49.0 0.9 1.9e-11 43.7 0.5 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain HTH_55 PF18622.1 EGF79720.1 - 0.12 12.7 0.0 0.45 10.9 0.0 2.1 1 0 0 1 1 1 0 RctB helix turn helix domain HEAT PF02985.22 EGF79720.1 - 0.18 12.2 0.6 3 8.3 0.1 3.6 2 0 0 2 2 2 0 HEAT repeat TB2_DP1_HVA22 PF03134.19 EGF79721.1 - 8e-26 89.8 6.1 1.8e-25 88.6 6.1 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TMEM223 PF14640.6 EGF79722.1 - 1.5e-43 148.8 0.0 1.8e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 223 TcfC PF16967.5 EGF79722.1 - 0.094 12.2 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 E-set like domain Glyco_hydro_47 PF01532.20 EGF79723.1 - 1.1e-109 367.4 0.0 1.7e-109 366.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_S41 PF03572.18 EGF79724.1 - 1.3e-09 37.8 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EGF79724.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EGF79724.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Peptidase_S41 PF03572.18 EGF79725.1 - 4.1e-11 42.7 0.0 7.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EGF79725.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EGF79725.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Lactamase_B PF00753.27 EGF79726.1 - 3.4e-16 59.8 0.1 5.3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGF79726.1 - 0.021 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MARVEL PF01284.23 EGF79727.1 - 9.6e-06 25.7 9.3 1.4e-05 25.1 9.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain Atg14 PF10186.9 EGF79729.1 - 2.1e-07 30.4 5.1 1.9e-06 27.2 5.0 2.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Aa_trans PF01490.18 EGF79730.1 - 9.6e-66 222.2 27.5 1.1e-65 221.9 27.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MGC-24 PF05283.11 EGF79731.1 - 0.0035 17.8 0.3 0.011 16.2 0.3 1.8 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin CD99L2 PF12301.8 EGF79731.1 - 0.0094 16.3 0.2 0.057 13.7 0.0 2.0 2 0 0 2 2 2 1 CD99 antigen like protein 2 Adeno_E3_CR2 PF02439.15 EGF79731.1 - 0.012 15.4 0.8 0.012 15.4 0.8 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF1180 PF06679.12 EGF79731.1 - 0.089 13.2 0.5 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CoatB PF10389.9 EGF79731.1 - 0.098 12.5 0.8 0.18 11.6 0.8 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B TMEM154 PF15102.6 EGF79731.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 EGF79731.1 - 0.18 11.8 0.2 0.33 10.9 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain SH3_1 PF00018.28 EGF79732.1 - 1e-05 25.0 0.1 2.1e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF79732.1 - 1.3e-05 24.9 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 EGF79732.1 - 0.0028 17.0 0.1 0.0028 17.0 0.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain T4SS_TraI PF16932.5 EGF79732.1 - 0.012 14.8 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer TMEM154 PF15102.6 EGF79732.1 - 0.12 12.3 0.0 0.45 10.4 0.0 1.8 1 1 1 2 2 2 0 TMEM154 protein family Alpha_GJ PF03229.13 EGF79732.1 - 1.1 9.8 7.8 0.22 12.1 2.3 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J PPR_2 PF13041.6 EGF79733.1 - 1e-15 57.6 1.7 9.3e-05 22.5 0.0 4.9 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 EGF79733.1 - 9.8e-14 50.6 2.4 0.01 16.0 0.0 6.0 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.7 EGF79733.1 - 7.7e-06 25.5 0.2 0.087 12.5 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 EGF79733.1 - 0.0022 18.1 0.4 8.4 6.6 0.0 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain MOR2-PAG1_C PF14225.6 EGF79733.1 - 0.074 12.9 0.4 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Citrate_synt PF00285.21 EGF79734.1 - 1.6e-111 372.9 0.1 1.4e-110 369.8 0.0 1.9 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain HAUS2 PF15003.6 EGF79734.1 - 0.031 14.0 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Pkinase PF00069.25 EGF79735.1 - 3.3e-53 180.7 0.0 5.5e-41 140.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79735.1 - 4e-20 72.2 0.0 3e-12 46.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF79735.1 - 0.00087 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF79735.1 - 0.0087 15.4 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGF79735.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Promethin PF16015.5 EGF79736.1 - 3e-10 40.0 10.5 3.2e-10 39.9 10.5 1.1 1 0 0 1 1 1 1 Promethin DUF4083 PF13314.6 EGF79736.1 - 6.9 6.7 5.6 13 5.8 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF4042 PF13251.6 EGF79737.1 - 2.9e-23 82.5 11.2 3.1e-23 82.4 0.8 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF4042) HEAT PF02985.22 EGF79737.1 - 3.2e-07 30.0 11.0 2.7 8.5 0.0 7.9 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 EGF79737.1 - 0.0026 17.7 3.4 1.7 8.8 0.1 4.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 EGF79737.1 - 0.041 13.8 2.7 1.5 8.8 0.0 4.7 5 0 0 5 5 5 0 Importin-beta N-terminal domain HEAT_EZ PF13513.6 EGF79737.1 - 0.041 14.4 9.7 5.3 7.6 0.1 5.6 4 1 1 5 5 5 0 HEAT-like repeat Ras PF00071.22 EGF79738.1 - 9.5e-49 165.1 0.0 1.1e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF79738.1 - 1.5e-29 102.7 0.0 3.3e-29 101.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF79738.1 - 2.2e-10 40.3 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EGF79738.1 - 0.00023 21.5 0.1 0.0014 19.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EGF79738.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGF79738.1 - 0.0027 17.8 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGF79738.1 - 0.0037 16.5 0.2 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 EGF79738.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 EGF79738.1 - 0.022 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EGF79738.1 - 0.031 14.2 0.1 8 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EGF79738.1 - 0.031 13.8 0.3 0.2 11.2 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 EGF79738.1 - 0.037 14.3 0.1 0.074 13.3 0.1 1.5 1 1 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 EGF79738.1 - 0.062 13.0 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGF79738.1 - 0.087 12.8 0.1 0.2 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGF79738.1 - 0.094 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGF79738.1 - 0.13 12.5 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain Romo1 PF10247.9 EGF79739.1 - 3.7e-24 84.9 3.9 4.5e-24 84.6 3.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGF79739.1 - 0.032 14.6 0.6 0.046 14.1 0.6 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family SURF1 PF02104.15 EGF79740.1 - 5.4e-41 140.8 0.0 6.9e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family GTP1_OBG PF01018.22 EGF79741.1 - 1.2e-35 122.4 5.3 1.7e-35 121.9 5.3 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 EGF79741.1 - 6.8e-23 80.9 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF79741.1 - 2.9e-10 39.9 0.0 1.3e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EGF79741.1 - 1.4e-05 24.7 0.0 2.6e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGF79741.1 - 0.0033 16.8 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EGF79741.1 - 0.091 13.3 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Cyclin_N PF00134.23 EGF79742.1 - 4.5e-13 49.1 0.8 3.2e-10 39.8 0.6 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 EGF79742.1 - 0.032 14.3 0.1 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EGF79742.1 - 0.07 13.5 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 Cyclin C-terminal domain FliS PF02561.14 EGF79742.1 - 0.08 13.2 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FliS Cyclin_C PF02984.19 EGF79742.1 - 4.9 7.3 6.9 0.51 10.4 0.3 2.8 3 2 0 3 3 3 0 Cyclin, C-terminal domain ADK PF00406.22 EGF79744.1 - 4.4e-46 156.7 0.0 4.9e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGF79744.1 - 4e-34 118.0 0.0 4.7e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF79744.1 - 1.9e-10 41.4 0.0 2.3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGF79744.1 - 8.6e-07 28.8 0.1 0.0034 17.1 0.0 2.1 1 1 1 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EGF79744.1 - 4.8e-06 26.8 0.0 1.2e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain CRISPR_Cse1 PF09481.10 EGF79744.1 - 0.008 15.3 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) dNK PF01712.19 EGF79744.1 - 0.02 14.7 0.0 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase SRP54 PF00448.22 EGF79744.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain JTB PF05439.12 EGF79747.1 - 0.036 14.1 3.4 0.3 11.1 1.5 2.3 2 1 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) SHIPPO-rpt PF07004.12 EGF79748.1 - 0.0058 17.5 0.3 0.087 13.8 0.0 2.7 3 0 0 3 3 3 1 Sperm-tail PG-rich repeat Folliculin PF11704.8 EGF79748.1 - 0.031 14.2 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ery_res_leader2 PF08057.11 EGF79748.1 - 0.18 12.3 0.2 0.75 10.4 0.2 2.1 1 0 0 1 1 1 0 Erythromycin resistance leader peptide DHC_N2 PF08393.13 EGF79749.1 - 1.4e-51 175.9 10.1 1.4e-51 175.9 10.1 4.3 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EGF79749.1 - 1.3e-28 99.9 0.5 5.9e-27 94.5 0.1 3.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EGF79749.1 - 6.8e-23 81.1 0.2 1.6e-19 70.1 0.1 2.9 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynein_C PF18199.1 EGF79749.1 - 3.1e-13 49.6 0.0 8.3e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGF79749.1 - 1.2e-11 44.2 0.1 1.2e-11 44.2 0.1 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 EGF79749.1 - 1.3e-10 41.5 1.8 2.6e-10 40.5 0.1 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF79749.1 - 1.1e-08 34.6 2.3 1.1e-08 34.5 0.4 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGF79749.1 - 5.6e-06 26.5 0.0 2.4e-05 24.5 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_heavy PF03028.15 EGF79749.1 - 6.4e-06 26.3 0.2 0.0024 17.9 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EGF79749.1 - 0.00022 21.1 0.3 0.00073 19.4 0.3 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGF79749.1 - 0.0017 18.6 0.0 0.3 11.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain TLD PF07534.16 EGF79749.1 - 0.019 15.2 0.1 0.074 13.3 0.1 2.1 1 0 0 1 1 1 0 TLD IstB_IS21 PF01695.17 EGF79749.1 - 0.043 13.5 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGF79749.1 - 0.11 12.8 0.0 12 6.2 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 EGF79749.1 - 0.12 12.0 0.0 19 4.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGF79749.1 - 4 7.9 5.8 31 5.1 0.0 4.0 4 0 0 4 4 4 0 ABC transporter DASH_Duo1 PF08651.10 EGF79749.1 - 5 7.0 9.4 23 4.8 2.4 4.4 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF745 PF05335.13 EGF79749.1 - 8.3 6.1 10.4 0.14 11.8 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Dynein_C PF18199.1 EGF79750.1 - 4e-15 55.8 0.0 6.1e-15 55.2 0.0 1.3 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain CDP-OH_P_transf PF01066.21 EGF79751.1 - 5.5e-16 59.1 1.0 5.5e-16 59.1 1.0 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Arteri_Gl PF00951.18 EGF79751.1 - 0.36 10.6 9.6 0.53 10.1 0.4 2.4 2 1 1 3 3 3 0 Arterivirus GL envelope glycoprotein DUF3382 PF11862.8 EGF79751.1 - 1.7 9.0 5.2 8.4 6.8 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) GCV_T PF01571.21 EGF79752.1 - 2.9e-87 292.3 0.1 3.7e-87 291.9 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGF79752.1 - 3.5e-20 71.7 0.1 8.8e-20 70.4 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GIT_SHD PF08518.11 EGF79753.1 - 8.6e-18 63.7 1.5 6.7e-10 38.4 0.3 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 EGF79753.1 - 2.2e-07 31.0 0.4 1.3e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Popeye PF04831.13 EGF79753.1 - 0.032 14.4 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Popeye protein conserved region Vps53_N PF04100.12 EGF79753.1 - 0.24 10.3 12.6 0.51 9.2 2.3 2.4 1 1 1 2 2 2 0 Vps53-like, N-terminal Cor1 PF04803.12 EGF79753.1 - 0.45 10.7 9.8 3.4 7.9 8.4 2.8 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF745 PF05335.13 EGF79753.1 - 0.48 10.1 7.7 1 9.1 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) BLOC1_2 PF10046.9 EGF79753.1 - 0.5 10.7 16.6 1.3 9.3 7.6 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EGF79753.1 - 0.59 8.9 20.1 1.5 7.7 17.4 2.9 3 1 0 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.14 EGF79753.1 - 2.5 8.4 17.2 7 7.0 12.9 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PI_PP_I PF18363.1 EGF79753.1 - 4.6 7.5 5.2 1.5 9.0 1.6 2.1 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain YabA PF06156.13 EGF79753.1 - 6.9 7.4 13.4 4 8.1 4.0 3.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 EGF79753.1 - 8.5 6.4 13.9 0.2 11.7 3.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Cluap1 PF10234.9 EGF79754.1 - 8.5e-107 356.5 6.4 1.6e-106 355.6 6.4 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 DUF3053 PF11254.8 EGF79754.1 - 4 6.9 6.9 0.6 9.7 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) RasGEF PF00617.19 EGF79755.1 - 4.3e-58 196.4 0.1 7.5e-58 195.6 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGF79755.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif CssAB PF16831.5 EGF79756.1 - 0.076 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 LPD16 PF18830.1 EGF79756.1 - 0.088 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 Acyltransferase PF01553.21 EGF79757.1 - 4.3e-31 107.3 0.0 6.3e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase AAA PF00004.29 EGF79758.1 - 6.2e-56 188.4 0.0 1.1e-42 145.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EGF79758.1 - 1.5e-26 92.6 3.4 5.4e-26 90.8 3.4 2.1 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EGF79758.1 - 2e-13 49.9 0.0 3.3e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGF79758.1 - 4.5e-11 43.4 4.8 1.5e-06 28.7 0.1 3.9 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGF79758.1 - 2e-07 31.4 1.2 0.0034 17.7 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_33 PF13671.6 EGF79758.1 - 2.4e-05 24.5 0.3 0.11 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 EGF79758.1 - 4.4e-05 23.5 0.1 0.056 13.4 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_18 PF13238.6 EGF79758.1 - 4.7e-05 24.0 0.0 0.057 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGF79758.1 - 5.1e-05 23.2 2.6 0.11 12.4 0.5 3.7 3 1 0 3 3 2 1 NACHT domain IstB_IS21 PF01695.17 EGF79758.1 - 5.3e-05 23.0 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EGF79758.1 - 7.5e-05 22.8 0.0 0.83 9.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 EGF79758.1 - 9.3e-05 22.2 0.0 0.02 14.6 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGF79758.1 - 0.0001 21.7 0.1 0.053 12.7 0.0 2.6 2 0 0 2 2 2 1 TIP49 P-loop domain Zeta_toxin PF06414.12 EGF79758.1 - 0.00011 21.5 0.1 0.16 11.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.14 EGF79758.1 - 0.00013 22.2 0.0 0.24 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGF79758.1 - 0.00016 21.7 0.1 0.63 10.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGF79758.1 - 0.00024 21.4 0.0 0.55 10.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.26 EGF79758.1 - 0.00047 19.9 0.0 0.079 12.7 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 EGF79758.1 - 0.00065 19.3 0.2 0.13 11.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGF79758.1 - 0.00084 19.0 2.2 1.5 8.3 0.1 4.1 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EGF79758.1 - 0.00086 18.7 0.2 0.16 11.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EGF79758.1 - 0.0022 17.8 0.0 1 9.1 0.0 2.9 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGF79758.1 - 0.0026 18.3 0.1 8.2 7.0 0.0 3.4 2 1 1 3 3 3 0 ABC transporter AAA_29 PF13555.6 EGF79758.1 - 0.0028 17.4 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 EGF79758.1 - 0.0042 17.1 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGF79758.1 - 0.015 15.5 0.1 10 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.18 EGF79758.1 - 0.017 15.0 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_17 PF13207.6 EGF79758.1 - 0.019 15.4 0.3 0.62 10.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGF79758.1 - 0.022 15.1 0.0 0.68 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGF79758.1 - 0.023 13.7 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 EGF79758.1 - 0.03 13.5 0.0 9 5.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EGF79758.1 - 0.036 13.8 0.0 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGF79758.1 - 0.041 13.5 0.7 0.9 9.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA12 PF10443.9 EGF79758.1 - 0.044 12.5 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein PhoH PF02562.16 EGF79758.1 - 0.074 12.5 0.2 5.7 6.3 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein ATPase_2 PF01637.18 EGF79758.1 - 0.096 12.6 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGF79758.1 - 0.099 12.6 0.1 5.2 6.9 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.11 EGF79758.1 - 0.14 12.0 0.0 2.8 7.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Mitofilin PF09731.9 EGF79759.1 - 1e-66 226.2 42.5 3.8e-65 221.0 42.5 2.1 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Tape_meas_lam_C PF09718.10 EGF79759.1 - 0.031 14.4 2.5 0.17 12.1 1.3 2.8 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Chlorosome_CsmC PF11098.8 EGF79759.1 - 0.046 13.7 11.8 0.023 14.7 8.7 2.0 2 0 0 2 2 2 0 Chlorosome envelope protein C PAP1 PF08601.10 EGF79759.1 - 0.24 11.1 12.8 0.47 10.1 12.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RNase_PH PF01138.21 EGF79760.1 - 5.7e-36 123.9 0.0 9.2e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGF79760.1 - 6.3e-07 29.3 0.0 1.6e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 TPH PF13868.6 EGF79761.1 - 2.3e-07 29.7 102.6 2.3e-07 29.7 102.6 2.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Med20 PF08612.11 EGF79762.1 - 4.7e-10 39.2 0.5 1.1e-09 38.0 0.5 1.5 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex PI3K_C2 PF00792.24 EGF79763.1 - 0.00019 21.4 0.1 0.011 15.7 0.0 3.3 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 tRNA-synt_2d PF01409.20 EGF79764.1 - 7.9e-90 300.6 0.0 1.1e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGF79764.1 - 8.8e-18 64.3 2.8 9.5e-18 64.3 0.2 2.5 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGF79764.1 - 0.00024 20.6 0.0 0.05 13.0 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EGF79764.1 - 0.003 16.7 0.0 0.0075 15.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGF79764.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Nrap_D4 PF17405.2 EGF79765.1 - 1.7e-50 171.3 0.0 3.3e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 EGF79765.1 - 1e-48 165.2 0.3 2.4e-48 164.1 0.3 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 EGF79765.1 - 6.2e-46 155.9 0.0 2.7e-44 150.6 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 EGF79765.1 - 1.6e-45 154.8 0.0 2.7e-44 150.8 0.1 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 EGF79765.1 - 1.6e-36 125.8 0.0 3.7e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EGF79765.1 - 4.5e-33 114.3 0.0 1.3e-32 112.9 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 C9orf72-like PF15019.6 EGF79765.1 - 0.034 13.7 0.2 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 C9orf72-like protein family AbiEi_3_N PF17194.4 EGF79765.1 - 0.13 12.3 0.0 6.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain UTP25 PF06862.12 EGF79767.1 - 4.3e-180 599.5 9.3 4.8e-180 599.4 9.3 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C PF00271.31 EGF79767.1 - 0.01 16.2 0.8 0.11 12.8 0.0 2.8 3 1 0 3 3 3 0 Helicase conserved C-terminal domain DEAD PF00270.29 EGF79767.1 - 0.054 13.3 0.0 3 7.6 0.0 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase KH_8 PF17903.1 EGF79768.1 - 8.7e-33 112.3 0.1 2.1e-32 111.0 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGF79768.1 - 0.0055 16.5 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 KH domain Mre11_DNA_bind PF04152.14 EGF79769.1 - 3.2e-48 164.2 0.3 1.3e-47 162.3 0.3 2.1 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGF79769.1 - 2.9e-14 54.1 0.2 4.7e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGF79769.1 - 0.00018 21.7 0.0 0.0027 17.9 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BolA PF01722.18 EGF79770.1 - 2.8e-20 72.4 0.2 7.2e-20 71.1 0.2 1.6 1 1 0 1 1 1 1 BolA-like protein Es2 PF09751.9 EGF79771.1 - 5.7e-88 296.5 8.5 5.7e-88 296.5 8.5 1.9 2 0 0 2 2 2 1 Nuclear protein Es2 Peptidase_C54 PF03416.19 EGF79772.1 - 3.2e-98 328.5 0.0 6.6e-98 327.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family C54 TFIID_30kDa PF03540.13 EGF79773.1 - 8.8e-26 89.6 0.2 1.4e-25 88.9 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 EGF79773.1 - 0.00015 21.7 0.5 0.00017 21.4 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Halogen_Hydrol PF10112.9 EGF79773.1 - 0.06 13.4 1.2 0.16 12.0 0.2 2.1 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SLX9 PF15341.6 EGF79773.1 - 0.15 12.4 3.5 0.92 9.9 0.7 2.1 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 HSP70 PF00012.20 EGF79774.1 - 1.9e-268 891.6 16.1 2.2e-268 891.4 16.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF79774.1 - 4.1e-14 52.1 6.6 1.9e-12 46.7 3.4 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGF79774.1 - 4.4e-05 23.3 0.0 8.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ploopntkinase3 PF18751.1 EGF79774.1 - 0.00069 19.6 0.4 0.026 14.4 0.0 2.7 3 0 0 3 3 3 1 P-loop Nucleotide Kinase3 FtsA PF14450.6 EGF79774.1 - 0.0027 18.1 9.6 0.32 11.4 0.6 3.8 3 1 0 3 3 3 2 Cell division protein FtsA DUF1798 PF08807.10 EGF79774.1 - 0.025 14.7 2.3 0.068 13.3 1.6 2.0 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Phage_TAC_8 PF10666.9 EGF79774.1 - 0.26 11.5 6.1 0.53 10.6 6.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 ST7 PF04184.12 EGF79774.1 - 0.69 8.3 2.4 1 7.7 2.4 1.2 1 0 0 1 1 1 0 ST7 protein Peptidase_S41 PF03572.18 EGF79775.1 - 7.3e-22 77.7 0.0 1.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S41 PDZ_4 PF17816.1 EGF79775.1 - 0.00013 22.3 0.0 0.62 10.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EGF79775.1 - 0.0002 21.1 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EGF79775.1 - 0.00022 21.5 0.1 1.4 9.3 0.0 2.8 2 0 0 2 2 2 2 PDZ domain DUF4311 PF14188.6 EGF79775.1 - 0.0024 17.7 0.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4311) UvrA_inter PF17760.1 EGF79775.1 - 0.0087 16.1 0.0 5.3 7.2 0.0 2.5 2 0 0 2 2 2 2 UvrA interaction domain DNA_pol3_beta_2 PF02767.16 EGF79775.1 - 0.0095 16.1 1.8 1.7 8.9 0.1 3.5 4 0 0 4 4 4 1 DNA polymerase III beta subunit, central domain Mac_assoc PF16628.5 EGF79775.1 - 0.0096 16.1 0.1 7.5 6.7 0.0 2.5 2 0 0 2 2 2 2 Unstructured region on maltose acetyltransferase LAMTOR PF15454.6 EGF79775.1 - 0.016 15.8 0.8 11 6.7 0.1 2.6 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Glyco_hydro_66 PF13199.6 EGF79775.1 - 0.024 13.3 0.0 6.2 5.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 66 PrgU PF09627.10 EGF79775.1 - 0.14 12.1 3.0 21 5.2 0.1 3.6 4 0 0 4 4 4 0 PrgU-like protein Peptidase_S41 PF03572.18 EGF79776.1 - 6.5e-15 55.1 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 DNA_pol3_beta_2 PF02767.16 EGF79776.1 - 0.12 12.6 0.1 1 9.6 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain PDZ_4 PF17816.1 EGF79776.1 - 0.14 12.6 0.0 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Acyltransferase PF01553.21 EGF79777.1 - 1.3e-21 76.6 0.0 2.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CDC24_OB1 PF17246.2 EGF79777.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 TC1 PF15063.6 EGF79778.1 - 0.059 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Thyroid cancer protein 1 SHR3_chaperone PF08229.11 EGF79780.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 MFS_1 PF07690.16 EGF79781.1 - 2.4e-16 59.6 50.6 4.2e-08 32.5 26.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF79781.1 - 0.0014 17.6 32.1 0.017 14.0 32.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.22 EGF79782.1 - 2.5e-71 240.8 0.0 4.5e-58 197.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3589 PF12141.8 EGF79782.1 - 0.069 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-mannosyltransferases CENP-O PF09496.10 EGF79783.1 - 0.069 13.1 0.2 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Cep57_MT_bd PF06657.13 EGF79783.1 - 0.14 12.6 0.9 0.3 11.6 0.1 2.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ANAPC8 PF04049.13 EGF79784.1 - 3.6e-26 91.9 0.1 1.3e-25 90.1 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EGF79784.1 - 8.7e-23 79.2 1.8 4.5e-05 23.1 0.3 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGF79784.1 - 2e-17 61.8 3.4 0.079 13.2 0.0 7.1 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGF79784.1 - 4.7e-16 58.1 5.0 0.0067 17.1 0.0 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGF79784.1 - 4.6e-15 54.4 10.1 0.15 12.2 0.0 7.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGF79784.1 - 2.2e-12 46.5 8.4 0.00093 19.4 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF79784.1 - 2.9e-12 47.0 1.0 0.0017 19.0 0.3 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGF79784.1 - 1e-11 45.2 2.5 0.04 14.4 0.1 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGF79784.1 - 2.1e-11 43.3 4.1 0.00063 19.4 0.2 4.5 3 2 2 5 5 5 3 TPR repeat ANAPC3 PF12895.7 EGF79784.1 - 1.4e-09 38.1 8.1 0.0022 18.2 0.1 5.0 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGF79784.1 - 1.5e-08 34.8 2.2 3.8 7.9 0.0 6.5 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF79784.1 - 5.1e-06 26.2 2.0 20 5.5 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF79784.1 - 1.2e-05 25.6 4.6 3.6 8.4 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.10 EGF79784.1 - 7e-05 22.0 1.3 0.023 13.7 0.0 3.1 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 EGF79784.1 - 0.00037 19.8 2.8 0.043 13.0 2.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF79784.1 - 0.00093 19.0 3.9 9.9 6.2 0.5 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF79784.1 - 0.012 15.7 1.7 7.5 6.8 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat CLU PF13236.6 EGF79785.1 - 3.9e-33 115.1 0.0 7.4e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 EGF79785.1 - 6.5e-15 55.2 11.0 2.4e-10 40.5 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGF79785.1 - 1.5e-13 51.2 1.0 4.2e-12 46.5 1.0 2.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_10 PF13374.6 EGF79785.1 - 1.2e-09 37.7 6.4 0.0017 18.2 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat PH PF00169.29 EGF79785.1 - 2.1e-07 31.4 0.1 4.3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 PH domain TPR_2 PF07719.17 EGF79785.1 - 7e-06 25.8 3.8 0.093 12.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF79785.1 - 0.00016 21.3 3.8 2.6 8.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF79785.1 - 0.00039 20.2 3.8 0.25 11.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF79785.1 - 0.0019 17.6 5.1 0.019 14.3 5.1 2.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 EGF79785.1 - 0.0038 17.3 4.7 0.43 10.9 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF79785.1 - 0.0057 17.1 0.3 0.14 12.7 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF79785.1 - 0.017 15.5 0.0 0.52 10.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF79785.1 - 0.036 14.7 2.3 0.23 12.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF79785.1 - 0.043 14.6 8.9 20 6.3 0.3 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF79785.1 - 0.19 12.4 3.6 15 6.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EGF79786.1 - 1.1e-82 278.2 0.0 1.6e-82 277.7 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 EGF79786.1 - 0.0025 15.2 1.4 0.0031 15.0 0.0 1.6 2 0 0 2 2 2 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_2 PF07719.17 EGF79786.1 - 0.015 15.4 1.1 0.54 10.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyrosinase PF00264.20 EGF79787.1 - 2.1e-41 142.6 1.0 1.3e-40 140.1 1.0 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase Branch PF02485.21 EGF79788.1 - 4.4e-22 78.8 0.2 7.6e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Nucleotid_trans PF03407.16 EGF79788.1 - 2e-18 67.1 0.0 1.3e-17 64.5 0.0 2.1 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Ank_5 PF13857.6 EGF79789.1 - 9.6e-06 25.8 0.1 3.6e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGF79789.1 - 0.0003 21.3 0.0 0.00062 20.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF79789.1 - 0.0012 19.4 0.0 0.0025 18.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGF79789.1 - 0.0021 18.4 0.0 0.033 14.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EGF79789.1 - 0.006 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat NPHI_C PF08469.10 EGF79789.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal SH3_9 PF14604.6 EGF79790.1 - 8.1e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF79790.1 - 1.4e-06 27.8 0.0 2.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF79790.1 - 0.00049 19.7 0.0 0.00083 19.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain tRNA_edit PF04073.15 EGF79791.1 - 0.0048 17.0 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain FHIPEP PF00771.20 EGF79792.1 - 0.0058 15.2 0.1 0.0058 15.2 0.1 1.1 1 0 0 1 1 1 1 FHIPEP family LEAP-2 PF07359.11 EGF79792.1 - 0.013 15.4 0.1 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EIIBC-GUT_N PF03612.14 EGF79792.1 - 0.026 14.3 2.2 0.026 14.3 2.2 1.4 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Borrelia_rep PF03183.13 EGF79792.1 - 0.082 12.9 0.2 0.082 12.9 0.2 2.0 2 0 0 2 2 2 0 Borrelia repeat protein Conotoxin PF02950.17 EGF79792.1 - 1.3 10.1 4.9 5 8.2 1.8 2.1 2 0 0 2 2 2 0 Conotoxin Presenilin PF01080.17 EGF79792.1 - 1.8 7.3 4.2 2 7.1 4.2 1.1 1 0 0 1 1 1 0 Presenilin CAV_VP3 PF04771.12 EGF79793.1 - 2.6e-05 24.4 1.9 22 5.2 0.0 5.7 1 1 3 6 6 6 2 Chicken anaemia virus VP-3 protein DUF851 PF05867.11 EGF79793.1 - 0.0024 17.4 6.2 35 3.8 0.0 5.6 1 1 5 6 6 6 1 Protein of unknown function (DUF851) Chorismate_bind PF00425.18 EGF79793.1 - 0.024 14.2 0.0 1.3e+02 1.9 0.0 4.1 4 0 0 4 4 4 0 chorismate binding enzyme SpoU_methylase PF00588.19 EGF79797.1 - 3.8e-27 95.2 0.0 4.3e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.6 EGF79797.1 - 0.088 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP GDI PF00996.18 EGF79798.1 - 1.4e-221 735.6 0.5 1.6e-221 735.4 0.5 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 EGF79798.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGF79798.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MBOAT PF03062.19 EGF79799.1 - 1.2e-36 126.8 18.4 1.6e-36 126.4 18.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGF79799.1 - 0.0016 18.7 1.9 0.0026 18.0 0.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF4570 PF15134.6 EGF79799.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) WD40 PF00400.32 EGF79800.1 - 8.4e-11 42.3 9.4 0.0034 18.2 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79800.1 - 5.2e-09 36.3 0.0 0.0065 16.7 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 EGF79800.1 - 0.00016 21.7 0.0 0.00041 20.4 0.0 1.5 1 1 0 1 1 1 1 Prp18 domain SRA1 PF07304.11 EGF79800.1 - 0.014 15.1 0.0 0.014 15.1 0.0 3.1 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) Pkinase PF00069.25 EGF79802.1 - 4.2e-30 105.0 0.0 5.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79802.1 - 1.7e-12 47.2 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF79802.1 - 2.9e-06 26.8 0.0 0.00053 19.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like AAA PF00004.29 EGF79803.1 - 1.4e-37 129.1 0.0 2e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF79803.1 - 8.6e-08 31.9 0.0 7.9e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EGF79803.1 - 9.8e-06 25.4 0.0 3.2e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF79803.1 - 4.7e-05 23.7 0.4 0.014 15.7 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EGF79803.1 - 8.2e-05 22.6 0.1 0.00032 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 EGF79803.1 - 0.0001 22.2 0.0 0.0004 20.3 0.0 2.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 EGF79803.1 - 0.0021 18.5 0.6 0.015 15.7 0.6 2.4 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EGF79803.1 - 0.0042 16.5 0.3 0.015 14.7 0.2 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGF79803.1 - 0.0058 15.9 0.0 0.017 14.3 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 EGF79803.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TniB PF05621.11 EGF79803.1 - 0.028 13.8 0.1 2 7.8 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EGF79803.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGF79803.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF79803.1 - 0.074 12.6 0.2 0.17 11.4 0.2 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGF79803.1 - 0.1 13.0 0.4 0.33 11.3 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGF79803.1 - 0.11 12.3 0.0 1.6 8.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 EGF79803.1 - 0.11 12.2 0.0 3.9 7.1 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGF79803.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PspC PF04024.12 EGF79804.1 - 0.16 11.8 0.2 0.31 10.9 0.2 1.4 1 0 0 1 1 1 0 PspC domain ABC_membrane PF00664.23 EGF79805.1 - 4e-59 200.5 31.1 3.7e-30 105.5 3.5 3.6 4 0 0 4 4 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGF79805.1 - 9.5e-51 171.9 0.0 1.9e-26 93.2 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF79805.1 - 6.9e-11 42.0 0.5 0.0014 18.1 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF79805.1 - 1.6e-07 31.4 0.4 0.003 17.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGF79805.1 - 6.7e-06 26.7 1.3 0.0046 17.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGF79805.1 - 8.8e-06 25.7 0.1 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGF79805.1 - 3e-05 23.7 0.4 0.11 12.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF79805.1 - 0.0007 19.5 0.5 4.2 7.1 0.1 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EGF79805.1 - 0.0014 18.8 3.1 0.95 9.5 0.2 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain Dynamin_N PF00350.23 EGF79805.1 - 0.0016 18.5 0.4 0.037 14.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EGF79805.1 - 0.0042 17.5 0.2 2.3 8.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 EGF79805.1 - 0.0064 15.5 0.2 0.41 9.6 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AtpR PF12966.7 EGF79805.1 - 0.026 15.0 2.3 0.17 12.3 0.2 3.1 2 0 0 2 2 2 0 N-ATPase, AtpR subunit AAA_22 PF13401.6 EGF79805.1 - 0.042 14.1 0.3 11 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGF79805.1 - 0.05 12.9 0.3 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGF79805.1 - 0.072 12.4 0.0 6.9 6.0 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EGF79805.1 - 0.08 12.7 0.3 2.6 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EGF79805.1 - 0.14 11.2 0.1 20 4.2 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA PF00004.29 EGF79805.1 - 0.26 11.7 0.7 21 5.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AIG1 PF04548.16 EGF79805.1 - 0.42 9.9 1.7 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 AIG1 family RRM_1 PF00076.22 EGF79806.1 - 1.4e-22 79.3 0.2 5.3e-09 35.8 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGF79806.1 - 0.00021 21.2 0.0 0.24 11.4 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGF79806.1 - 0.019 14.6 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flu_M2 PF00599.17 EGF79809.1 - 0.27 11.3 0.8 1.5 9.0 0.0 2.4 3 0 0 3 3 3 0 Influenza Matrix protein (M2) RhoGEF PF00621.20 EGF79810.1 - 2.8e-36 125.5 0.8 4e-17 63.0 0.0 2.7 1 1 1 2 2 2 2 RhoGEF domain PH PF00169.29 EGF79810.1 - 2.3e-07 31.3 0.4 6e-07 29.9 0.4 1.8 1 0 0 1 1 1 1 PH domain DUF2013 PF09431.10 EGF79810.1 - 0.047 13.9 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) PTCB-BRCT PF12738.7 EGF79811.1 - 3.6e-26 90.9 6.6 9.9e-20 70.3 0.6 3.6 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 EGF79811.1 - 6.4e-20 71.3 4.8 5.4e-09 36.3 0.1 5.1 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGF79811.1 - 2.1e-11 43.5 1.5 3.8e-09 36.3 0.3 3.1 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EGF79811.1 - 5.4e-09 36.3 2.6 0.0086 16.5 0.0 4.7 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGF79811.1 - 0.0016 18.7 0.8 0.13 12.6 0.0 3.4 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain PKcGMP_CC PF16808.5 EGF79813.1 - 1.4e-05 24.8 8.9 0.027 14.3 0.1 3.0 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase BRE1 PF08647.11 EGF79813.1 - 0.00023 21.2 6.7 0.00024 21.1 2.5 2.3 1 1 1 2 2 2 1 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 EGF79813.1 - 0.0016 18.3 7.8 0.0027 17.6 7.8 1.5 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EGF79813.1 - 0.0022 16.9 11.0 0.04 12.8 5.0 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein CEP63 PF17045.5 EGF79813.1 - 0.0025 17.8 10.5 0.052 13.4 2.1 2.3 1 1 1 2 2 2 2 Centrosomal protein of 63 kDa Fez1 PF06818.15 EGF79813.1 - 0.0031 18.0 7.7 0.0042 17.6 7.7 1.2 1 0 0 1 1 1 1 Fez1 Filament PF00038.21 EGF79813.1 - 0.0066 16.1 8.8 0.3 10.6 2.8 2.1 1 1 1 2 2 2 2 Intermediate filament protein FlgN PF05130.12 EGF79813.1 - 0.0073 16.8 7.2 0.0084 16.6 6.4 1.5 1 1 0 1 1 1 1 FlgN protein Cep57_MT_bd PF06657.13 EGF79813.1 - 0.01 16.3 9.3 0.075 13.5 0.3 3.3 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 LemA PF04011.12 EGF79813.1 - 0.016 15.0 0.8 0.068 13.0 0.8 2.0 1 1 0 1 1 1 0 LemA family TRAF_BIRC3_bd PF16673.5 EGF79813.1 - 0.021 14.6 0.8 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain bZIP_1 PF00170.21 EGF79813.1 - 0.03 14.4 0.4 0.03 14.4 0.4 3.3 3 1 2 5 5 4 0 bZIP transcription factor Fib_alpha PF08702.10 EGF79813.1 - 0.032 14.4 6.0 0.37 11.0 3.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 EGF79813.1 - 0.034 14.4 3.7 0.056 13.7 1.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 EGF79813.1 - 0.067 13.3 11.5 0.096 12.8 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DDE_Tnp_IS240 PF13610.6 EGF79813.1 - 0.071 13.3 1.3 0.16 12.2 0.2 1.9 1 1 1 2 2 2 0 DDE domain ZapB PF06005.12 EGF79813.1 - 0.076 13.5 8.4 1.4 9.4 0.3 3.0 1 1 1 2 2 2 0 Cell division protein ZapB FOXP-CC PF16159.5 EGF79813.1 - 0.076 13.6 6.4 0.2 12.3 1.6 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Prefoldin_2 PF01920.20 EGF79813.1 - 0.078 12.9 7.3 7.8 6.5 0.2 3.2 2 1 1 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.7 EGF79813.1 - 0.094 12.9 8.6 0.94 9.6 1.6 2.4 1 1 1 2 2 2 0 Tropomyosin like SHE3 PF17078.5 EGF79813.1 - 0.095 12.4 6.4 0.23 11.1 3.9 1.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CortBP2 PF09727.9 EGF79813.1 - 0.14 12.0 9.9 0.22 11.4 9.9 1.3 1 1 0 1 1 1 0 Cortactin-binding protein-2 Atg14 PF10186.9 EGF79813.1 - 0.18 10.8 8.3 0.2 10.7 8.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YscO PF07321.12 EGF79813.1 - 0.23 11.4 13.0 4.7 7.1 0.7 3.1 1 1 1 3 3 3 0 Type III secretion protein YscO DUF641 PF04859.12 EGF79813.1 - 0.23 11.8 8.0 2.5 8.4 2.1 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.11 EGF79813.1 - 0.26 11.7 8.9 0.33 11.4 0.4 3.5 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 EGF79813.1 - 0.28 11.6 9.5 0.72 10.3 4.9 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2205 PF10224.9 EGF79813.1 - 0.31 11.1 7.0 0.75 9.8 0.4 2.5 2 1 0 2 2 2 0 Short coiled-coil protein TPR_MLP1_2 PF07926.12 EGF79813.1 - 0.39 10.8 13.3 0.49 10.4 4.1 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 EGF79813.1 - 0.43 10.8 5.5 1.7 8.8 0.4 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-F_leu_zip PF10473.9 EGF79813.1 - 0.46 10.5 9.3 0.32 11.0 7.0 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EGF79813.1 - 0.59 10.7 8.5 1.3 9.5 8.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 EGF79813.1 - 0.6 10.8 6.5 1.4 9.6 0.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 EGF79813.1 - 0.94 8.7 4.0 0.98 8.6 2.9 1.5 1 1 1 2 2 2 0 TMPIT-like protein ABC_tran_CTD PF16326.5 EGF79813.1 - 2 8.7 10.6 0.57 10.5 0.4 3.0 3 1 1 4 4 3 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 EGF79813.1 - 2.4 7.6 8.6 3.4 7.1 8.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit MerR-DNA-bind PF09278.11 EGF79814.1 - 0.005 17.3 0.1 0.0096 16.4 0.1 1.5 1 0 0 1 1 1 1 MerR, DNA binding DUF1640 PF07798.11 EGF79814.1 - 0.0062 16.6 0.4 0.0071 16.4 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 EGF79814.1 - 0.021 15.0 0.7 0.037 14.3 0.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 EGF79814.1 - 0.027 14.1 1.1 0.054 13.1 1.1 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIVA PF05103.13 EGF79814.1 - 0.028 14.5 0.7 0.034 14.2 0.1 1.5 2 0 0 2 2 2 0 DivIVA protein CLZ PF16526.5 EGF79814.1 - 0.042 14.2 0.7 0.092 13.1 0.3 1.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 EGF79814.1 - 0.061 13.7 0.2 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) KLRAQ PF10205.9 EGF79814.1 - 0.066 13.4 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein GIT_CC PF16559.5 EGF79814.1 - 0.071 13.0 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor VPS11_C PF12451.8 EGF79814.1 - 0.084 13.1 1.3 0.98 9.7 0.6 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF4635 PF15466.6 EGF79814.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DivIC PF04977.15 EGF79814.1 - 0.12 12.1 1.3 0.2 11.4 0.3 1.8 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 EGF79814.1 - 0.13 12.8 0.0 12 6.5 0.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MctB PF11382.8 EGF79814.1 - 0.14 11.9 0.6 0.32 10.6 0.4 1.6 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB SBDS PF01172.18 EGF79815.1 - 1.1e-15 57.4 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Nic96 PF04097.14 EGF79816.1 - 2.4e-124 416.1 0.0 3e-124 415.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Methyltransf_16 PF10294.9 EGF79817.1 - 7.3e-22 77.9 0.2 1.4e-21 77.0 0.2 1.4 1 0 0 1 1 1 1 Lysine methyltransferase FAM86 PF14904.6 EGF79817.1 - 3.3e-07 30.3 0.2 7.2e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function PrmA PF06325.13 EGF79817.1 - 1.1e-06 28.3 0.1 1.6e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGF79817.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGF79817.1 - 0.011 16.5 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SRP19 PF01922.17 EGF79818.1 - 1.4e-27 96.5 0.0 2.5e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein CCDC92 PF14916.6 EGF79819.1 - 0.043 13.6 2.3 0.73 9.6 0.1 3.8 4 0 0 4 4 4 0 Coiled-coil domain of unknown function HALZ PF02183.18 EGF79819.1 - 0.61 10.4 0.0 0.61 10.4 0.0 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper Chalcone_3 PF16036.5 EGF79819.1 - 9 6.4 7.6 4.8 7.3 1.6 3.4 3 0 0 3 3 3 0 Chalcone isomerase-like LRR_6 PF13516.6 EGF79820.1 - 4.4e-19 66.9 6.6 0.0035 17.3 0.0 8.4 8 0 0 8 8 8 6 Leucine Rich repeat LRR_1 PF00560.33 EGF79820.1 - 4.4e-08 32.6 2.0 7.1 7.6 0.9 6.9 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.7 EGF79820.1 - 4.7e-08 33.2 14.9 0.0056 17.1 1.6 6.1 4 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF79820.1 - 0.00011 21.8 11.2 3.4 7.5 0.4 6.3 5 1 0 5 5 5 3 Leucine rich repeat PX PF00787.24 EGF79821.1 - 3e-20 72.3 0.2 1e-19 70.6 0.2 2.0 1 0 0 1 1 1 1 PX domain Abhydrolase_1 PF00561.20 EGF79821.1 - 0.042 13.5 0.8 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3135 PF11333.8 EGF79821.1 - 0.069 13.4 1.2 0.27 11.5 1.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) UQ_con PF00179.26 EGF79822.1 - 1.7e-33 115.2 0.0 2.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Polyoma_coat PF00718.20 EGF79823.1 - 0.0039 16.5 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Polyomavirus coat protein Cwf_Cwc_15 PF04889.12 EGF79824.1 - 2.2e-61 207.8 19.7 2.9e-61 207.3 19.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein rRNA_processing PF08524.11 EGF79824.1 - 0.39 10.7 13.5 0.1 12.6 7.2 2.3 2 0 0 2 2 2 0 rRNA processing MFAP1 PF06991.11 EGF79824.1 - 3 7.6 24.3 5.3 6.8 24.3 1.4 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing MeaB PF03308.16 EGF79825.1 - 0.0097 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGF79825.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RHSP PF07999.11 EGF79825.1 - 0.035 12.9 0.1 0.5 9.1 0.0 2.2 2 1 0 2 2 2 0 Retrotransposon hot spot protein ATPase PF06745.13 EGF79825.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EGF79825.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NMT1 PF09084.11 EGF79827.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Asp PF00026.23 EGF79829.1 - 5.5e-10 39.2 0.0 1.4e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease M PF02370.16 EGF79831.1 - 0.064 13.8 3.1 1.9 9.3 0.2 2.8 2 0 0 2 2 2 0 M protein repeat HOOK PF05622.12 EGF79831.1 - 0.11 10.7 2.0 0.15 10.2 2.0 1.2 1 0 0 1 1 1 0 HOOK protein TMPIT PF07851.13 EGF79831.1 - 0.3 10.3 0.7 0.38 9.9 0.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 EGF79831.1 - 0.3 11.1 2.1 0.88 9.6 2.1 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DnaJ-X PF14308.6 EGF79832.1 - 3.4e-29 101.8 1.3 4.5e-28 98.1 1.3 2.2 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF79832.1 - 1.5e-22 79.5 0.8 3.2e-22 78.4 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EGF79833.1 - 5.6e-12 45.6 0.0 2.1e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF79833.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HSDR_N PF04313.14 EGF79833.1 - 0.00048 20.1 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.22 EGF79833.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF79833.1 - 0.0079 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF79833.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF79833.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF79833.1 - 0.019 13.7 0.6 0.029 13.1 0.6 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF79833.1 - 0.021 14.1 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF79833.1 - 0.079 12.5 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF79833.1 - 0.16 11.9 0.4 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF1539 PF07560.11 EGF79834.1 - 0.021 14.9 6.2 0.44 10.6 0.4 3.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) Asp PF00026.23 EGF79835.1 - 8.7e-12 45.1 0.3 1.3e-11 44.5 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79835.1 - 0.0044 16.8 0.2 0.048 13.5 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF3253 PF11625.8 EGF79836.1 - 0.11 12.8 0.0 25 5.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3253) DUF3704 PF12488.8 EGF79836.1 - 0.76 9.5 3.4 1.1e+02 2.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) OEP PF02321.18 EGF79838.1 - 1.1 9.0 9.7 1.5 8.6 9.7 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein FliD_N PF02465.18 EGF79838.1 - 4.9 7.9 5.8 15 6.3 5.3 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus 5_nucleotid_C PF02872.18 EGF79839.1 - 1.6e-34 119.4 0.0 3.2e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGF79839.1 - 1.5e-12 48.5 0.2 2.3e-12 47.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Asp PF00026.23 EGF79840.1 - 7.4e-13 48.6 1.1 3.5e-12 46.4 1.1 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF79840.1 - 0.00064 19.5 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Arylesterase PF01731.20 EGF79841.1 - 1.4e-16 60.4 0.3 2.2e-15 56.6 0.1 2.8 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 EGF79841.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.3 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EGF79841.1 - 0.13 12.4 0.0 1 9.5 0.0 2.4 3 0 0 3 3 3 0 Strictosidine synthase DUF3336 PF11815.8 EGF79842.1 - 3.3e-36 124.0 0.1 5.1e-36 123.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGF79842.1 - 4.3e-18 66.2 0.0 6.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2013 PF09431.10 EGF79843.1 - 1.3e-30 106.4 4.6 2.6e-30 105.4 4.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Yip1 PF04893.17 EGF79844.1 - 3.3e-11 43.2 17.9 7.1e-11 42.1 17.9 1.5 1 1 0 1 1 1 1 Yip1 domain YrhC PF14143.6 EGF79844.1 - 0.092 12.8 3.3 0.28 11.3 3.3 1.9 1 0 0 1 1 1 0 YrhC-like protein MRAP PF15183.6 EGF79844.1 - 0.69 9.9 0.0 0.69 9.9 0.0 3.2 3 1 0 3 3 3 0 Melanocortin-2 receptor accessory protein family AFP_2 PF18815.1 EGF79845.1 - 0.12 12.6 0.7 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat AFP_2 PF18815.1 EGF79846.1 - 0.12 12.7 0.7 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Histone PF00125.24 EGF79847.1 - 3.1e-41 140.8 1.3 3.8e-41 140.5 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGF79847.1 - 0.00012 22.1 0.3 0.00019 21.5 0.3 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGF79847.1 - 0.0011 19.3 0.2 0.0017 18.7 0.2 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGF79847.1 - 0.0078 16.3 0.2 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGF79847.1 - 0.022 15.0 0.9 0.043 14.1 0.9 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRM13 PF05206.14 EGF79848.1 - 2.6e-59 200.9 0.2 3.6e-59 200.4 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_31 PF13847.6 EGF79848.1 - 0.00016 21.5 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-U11-48K PF05253.12 EGF79848.1 - 0.012 15.5 2.0 0.042 13.8 2.0 2.1 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Methyltransf_12 PF08242.12 EGF79848.1 - 0.021 15.6 0.0 0.04 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.6 EGF79849.1 - 0.0018 19.0 10.3 0.57 11.2 3.8 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 EGF79849.1 - 0.088 13.3 0.3 0.37 11.3 0.3 2.1 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 EGF79849.1 - 3.9 8.1 16.1 0.74 10.4 4.3 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-BED PF02892.15 EGF79849.1 - 5.8 7.0 8.9 24 5.1 2.1 2.9 2 0 0 2 2 2 0 BED zinc finger Abhydrolase_1 PF00561.20 EGF79851.1 - 1.7e-21 77.1 0.1 4.8e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF79851.1 - 3.3e-16 59.3 0.0 5.7e-16 58.5 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF79851.1 - 4.3e-13 50.4 0.0 5.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EGF79851.1 - 0.0038 16.8 0.1 0.0086 15.6 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 EGF79851.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) ADK PF00406.22 EGF79852.1 - 2.3e-29 102.4 0.1 3.8e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EGF79852.1 - 3.7e-16 59.8 0.0 1.3e-09 38.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGF79852.1 - 9.6e-05 22.6 0.3 0.001 19.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF79852.1 - 0.0071 16.9 0.1 3.6 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGF79852.1 - 0.043 14.1 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EGF79852.1 - 0.05 13.9 0.2 0.58 10.4 0.0 2.1 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain RFX_DNA_binding PF02257.15 EGF79853.1 - 0.0015 19.1 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain BAF250_C PF12031.8 EGF79853.1 - 0.013 14.8 0.8 0.017 14.5 0.0 1.5 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa DCB PF16213.5 EGF79853.1 - 0.19 11.3 1.3 0.37 10.4 0.4 1.9 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 ARID PF01388.21 EGF79854.1 - 4.5e-20 72.1 0.1 7e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Smg4_UPF3 PF03467.15 EGF79854.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family CYTH PF01928.21 EGF79855.1 - 7.5e-21 74.9 0.3 9.7e-21 74.5 0.3 1.1 1 0 0 1 1 1 1 CYTH domain SH3_9 PF14604.6 EGF79856.1 - 1.7e-19 69.4 0.1 2e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGF79856.1 - 5.4e-16 57.9 2.2 6.3e-09 35.3 0.1 2.8 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGF79856.1 - 4.4e-11 42.3 0.0 1.5e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain RhoGEF PF00621.20 EGF79856.1 - 5.2e-11 43.1 2.4 7.9e-11 42.5 0.2 2.1 2 0 0 2 2 2 1 RhoGEF domain Med7 PF05983.11 EGF79857.1 - 1.3e-26 93.9 6.9 8.6e-19 68.4 2.4 2.1 1 1 1 2 2 2 2 MED7 protein Ribosomal_L16 PF00252.18 EGF79858.1 - 1.5e-44 151.2 0.1 1.9e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e P2X_receptor PF00864.19 EGF79859.1 - 3.7e-18 65.7 2.6 2.2e-09 36.9 0.1 2.7 3 0 0 3 3 3 2 ATP P2X receptor WD40 PF00400.32 EGF79860.1 - 2.7e-17 62.8 7.3 0.0017 19.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79860.1 - 1.2e-07 31.9 0.0 0.00079 19.7 0.0 4.5 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF79860.1 - 0.0097 15.8 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A R2K_3 PF14243.6 EGF79860.1 - 0.035 14.1 0.1 0.068 13.2 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Sdh5 PF03937.16 EGF79861.1 - 3.7e-27 94.1 0.4 4.5e-27 93.8 0.4 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ank_2 PF12796.7 EGF79862.1 - 3.7e-08 33.8 6.0 0.012 16.1 1.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF79862.1 - 0.0094 16.5 5.8 35 5.1 0.1 5.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF79862.1 - 0.014 15.7 2.0 80 3.7 0.0 5.0 2 1 3 5 5 5 0 Ankyrin repeats (many copies) DUF2681 PF10883.8 EGF79863.1 - 0.98 9.9 8.4 6.6 7.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) ER-remodelling PF14755.6 EGF79863.1 - 1.4 9.2 15.8 1.8 8.9 3.6 2.6 1 1 2 3 3 3 0 Intracellular membrane remodeller WD40 PF00400.32 EGF79865.1 - 2.9e-11 43.7 10.3 1.6e-05 25.5 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Aminotran_5 PF00266.19 EGF79866.1 - 3.3e-32 111.9 0.1 4.3e-30 104.9 0.1 2.2 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.17 EGF79866.1 - 9.6e-31 106.5 0.0 2.1e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGF79866.1 - 7.9e-14 51.6 0.1 5.5e-13 48.8 0.0 2.3 2 1 0 2 2 2 1 MOSC N-terminal beta barrel domain Nuc_sug_transp PF04142.15 EGF79867.1 - 9.4e-112 373.2 19.2 1.2e-111 372.9 19.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGF79867.1 - 0.0023 18.1 7.5 0.0023 18.1 7.5 2.7 2 1 0 2 2 2 1 EamA-like transporter family Nuc_sug_transp PF04142.15 EGF79868.1 - 3.2e-81 272.9 21.9 9.6e-80 268.1 21.9 2.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGF79868.1 - 2.2e-09 37.0 13.8 2.2e-09 37.0 13.8 2.4 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 EGF79868.1 - 2.1e-06 28.0 40.2 0.00024 21.3 1.8 3.2 2 1 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EGF79868.1 - 1.9e-05 24.1 0.3 1.9e-05 24.1 0.3 2.9 3 1 0 3 3 3 1 Purine nucleobase transmembrane transport TPT PF03151.16 EGF79868.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 2.5 2 1 0 3 3 3 1 Triose-phosphate Transporter family SLC35F PF06027.12 EGF79868.1 - 0.007 15.9 10.0 0.007 15.9 10.0 2.5 3 0 0 3 3 3 2 Solute carrier family 35 CRT-like PF08627.10 EGF79868.1 - 0.056 12.4 11.7 0.39 9.6 0.1 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like IncF PF17626.2 EGF79868.1 - 2.3 8.6 7.0 0.29 11.5 1.9 2.2 2 0 0 2 2 2 0 Inclusion membrane protein F PMI_typeI PF01238.21 EGF79869.1 - 2.3e-116 389.1 0.0 2.6e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EGF79869.1 - 0.12 12.3 0.0 24 4.8 0.0 2.7 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF2407_C PF13373.6 EGF79870.1 - 5.3e-23 81.7 3.9 2.3e-22 79.7 3.9 2.0 1 1 0 1 1 1 1 DUF2407 C-terminal domain VCBS PF13517.6 EGF79870.1 - 1e-20 74.1 14.3 0.0021 18.6 0.7 7.4 5 1 2 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGF79870.1 - 0.00031 20.8 18.0 0.19 11.9 0.2 6.4 7 0 0 7 7 7 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 EGF79870.1 - 0.0054 16.1 0.5 7.1 6.0 0.0 4.6 5 1 1 6 6 6 1 Insecticide toxin TcdB middle/N-terminal region DNA_pol_E_B PF04042.16 EGF79871.1 - 8.8e-48 162.4 0.2 1.5e-47 161.7 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3829 PF12889.7 EGF79871.1 - 0.073 12.5 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Methyltransf_28 PF02636.17 EGF79872.1 - 8.8e-37 127.1 0.0 1.1e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EGF79872.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MTHFR PF02219.17 EGF79873.1 - 2.5e-117 391.3 0.0 3.2e-117 391.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TMEM18 PF14770.6 EGF79874.1 - 1.2e-26 93.0 8.6 1.3e-26 92.9 8.6 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 FtsX PF02687.21 EGF79874.1 - 0.61 10.6 9.7 0.92 10.0 9.7 1.4 1 0 0 1 1 1 0 FtsX-like permease family Cyto_heme_lyase PF01265.17 EGF79875.1 - 7.7e-53 180.0 4.6 8e-52 176.6 4.6 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF4246 PF14033.6 EGF79876.1 - 1.5e-28 100.1 0.0 2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) ATPase PF06745.13 EGF79879.1 - 0.015 14.6 0.1 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 EGF79879.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 EGF79879.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGF79879.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RHSP PF07999.11 EGF79879.1 - 0.03 13.1 0.2 0.62 8.8 0.0 2.4 2 1 0 2 2 2 0 Retrotransposon hot spot protein DAP3 PF10236.9 EGF79879.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 bPH_4 PF06713.11 EGF79881.1 - 0.1 12.7 0.0 15 5.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial PH domain AAA_22 PF13401.6 EGF79882.1 - 0.1 12.9 0.0 1 9.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain GshA PF08886.11 EGF79882.1 - 0.16 10.5 0.0 0.28 9.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase Pkinase PF00069.25 EGF79883.1 - 2.7e-13 49.9 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79883.1 - 1.8e-07 30.7 0.0 2.2e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF79883.1 - 2.9e-05 23.5 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF79883.1 - 0.00054 19.9 0.0 0.0049 16.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF79883.1 - 0.006 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF79883.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Uso1_p115_C PF04871.13 EGF79885.1 - 0.00032 21.1 0.7 0.00032 21.1 0.7 2.0 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region FAM76 PF16046.5 EGF79885.1 - 0.05 13.0 0.1 0.05 13.0 0.1 1.9 2 0 0 2 2 2 0 FAM76 protein F-box-like PF12937.7 EGF79886.1 - 5.9e-09 35.7 3.0 1.1e-07 31.6 2.2 3.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGF79886.1 - 0.0023 17.8 0.6 0.0023 17.8 0.6 3.1 4 0 0 4 4 4 1 F-box domain BAR PF03114.18 EGF79887.1 - 2.6e-33 115.7 6.2 3.8e-33 115.1 6.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGF79887.1 - 6.1e-14 51.4 0.1 1.1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF79887.1 - 1.4e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF79887.1 - 3.2e-12 45.9 0.1 5.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.9 EGF79887.1 - 7.6e-05 22.0 4.9 0.00014 21.1 4.9 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking TMF_TATA_bd PF12325.8 EGF79887.1 - 0.00041 20.5 6.6 0.0013 19.0 6.6 1.9 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Chibby PF14645.6 EGF79887.1 - 0.0032 17.8 1.4 0.012 16.1 1.4 2.0 1 0 0 1 1 1 1 Chibby family Sec34 PF04136.15 EGF79887.1 - 0.9 9.4 8.7 1.7 8.5 8.7 1.5 1 0 0 1 1 1 0 Sec34-like family Elf1 PF05129.13 EGF79888.1 - 0.041 13.9 3.0 0.3 11.1 2.9 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_4 PF14570.6 EGF79888.1 - 1.2 9.0 6.1 2.8 7.8 6.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Arrestin_C PF02752.22 EGF79889.1 - 2e-10 41.3 4.3 3.9e-08 33.8 1.6 3.0 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Lipase_3 PF01764.25 EGF79890.1 - 5.6e-32 110.6 0.0 1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGF79890.1 - 0.0001 21.9 0.2 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EGF79890.1 - 0.004 16.9 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EGF79890.1 - 0.055 14.1 0.0 0.071 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Proteasome PF00227.26 EGF79891.1 - 4.4e-50 169.8 0.1 6.3e-50 169.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit mRNA_triPase PF02940.15 EGF79891.1 - 5.7e-38 130.8 2.0 5.7e-38 130.8 2.0 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Proteasome_A_N PF10584.9 EGF79891.1 - 0.00029 20.4 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PNRC PF15365.6 EGF79892.1 - 1.3e-08 34.4 1.7 1.3e-08 34.4 1.7 2.6 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Ccdc124 PF06244.12 EGF79893.1 - 1.4e-29 103.3 11.9 3e-29 102.2 11.9 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 EGF79893.1 - 1.8e-07 31.4 1.1 1.8e-07 31.4 1.1 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box CHDNT PF08073.12 EGF79893.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 EGF79893.1 - 0.18 12.4 10.9 2.5 8.6 10.6 2.2 1 1 0 1 1 1 0 YABBY protein Acetyltransf_7 PF13508.7 EGF79895.1 - 5e-08 33.3 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF79895.1 - 5.2e-07 29.9 0.4 1.1e-06 28.9 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF79895.1 - 7e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGF79895.1 - 0.00073 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGF79895.1 - 0.001 19.2 0.2 0.0022 18.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF79895.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Thioredoxin PF00085.20 EGF79896.1 - 8.2e-55 183.1 0.2 2.9e-26 91.5 0.0 3.7 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EGF79896.1 - 3.4e-34 118.4 0.3 8.3e-23 81.2 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGF79896.1 - 9e-07 29.0 0.0 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGF79896.1 - 2.4e-06 28.0 0.2 0.16 12.5 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGF79896.1 - 2.2e-05 24.7 0.0 0.72 10.2 0.0 4.0 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 EGF79896.1 - 3.2e-05 23.4 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family ERp29_N PF07912.13 EGF79896.1 - 0.00011 22.4 0.0 0.14 12.3 0.0 3.5 3 1 0 3 3 3 1 ERp29, N-terminal domain Calsequestrin PF01216.17 EGF79896.1 - 0.00019 20.6 0.8 0.00031 19.9 0.8 1.4 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.21 EGF79896.1 - 0.00037 20.4 0.1 0.16 11.9 0.0 3.3 2 2 1 3 3 3 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGF79896.1 - 0.012 15.4 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 EGF79896.1 - 0.21 11.7 0.3 0.75 9.9 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin PALP PF00291.25 EGF79897.1 - 3.1e-63 214.0 0.1 4.1e-63 213.5 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EGF79897.1 - 1e-09 38.7 0.1 4e-06 27.2 0.0 2.9 2 0 0 2 2 2 2 CBS domain BTB PF00651.31 EGF79898.1 - 2.1e-08 34.3 0.0 4.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 EGF79899.1 - 1.2e-37 128.4 3.0 7.2e-11 42.5 0.0 3.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF79899.1 - 4.6e-25 87.4 0.0 3.4e-08 33.6 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF79899.1 - 9.7e-22 74.7 0.0 0.00013 22.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EGF79899.1 - 2.8e-18 65.5 0.1 0.00057 20.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EGF79899.1 - 8e-16 58.2 0.0 0.00016 22.2 0.0 4.2 2 1 1 4 4 4 4 Ankyrin repeats (many copies) fn3 PF00041.21 EGF79899.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain TPT PF03151.16 EGF79900.1 - 6.6e-31 107.7 23.6 7.8e-31 107.5 23.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGF79900.1 - 2e-10 41.0 40.0 1e-07 32.2 14.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EGF79900.1 - 0.00046 19.5 19.3 0.00096 18.5 19.3 1.5 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport NOC3p PF07540.11 EGF79901.1 - 2e-30 105.1 0.5 2e-30 105.1 0.5 3.1 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.17 EGF79901.1 - 1.2e-20 74.2 4.7 2e-20 73.5 1.5 2.4 2 0 0 2 2 2 1 CBF/Mak21 family PDE4_UCR PF18100.1 EGF79901.1 - 0.21 12.2 2.2 0.85 10.3 0.2 3.0 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) zf-RanBP PF00641.18 EGF79902.1 - 4.8e-24 83.4 20.2 2.3e-08 33.2 0.9 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 EGF79902.1 - 0.00043 20.3 9.3 0.5 10.4 9.3 2.6 1 1 0 1 1 1 1 Double zinc ribbon Myb_Cef PF11831.8 EGF79902.1 - 0.00062 19.4 4.0 0.00071 19.2 2.2 1.9 2 0 0 2 2 2 1 pre-mRNA splicing factor component Vps36-NZF-N PF16988.5 EGF79902.1 - 0.013 14.9 16.0 0.16 11.4 1.8 4.0 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EGF79902.1 - 0.015 15.3 6.1 0.49 10.5 0.1 3.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Tnp_zf-ribbon_2 PF13842.6 EGF79902.1 - 2.4 9.1 14.8 2.5 9.0 0.9 3.4 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Thg1 PF04446.12 EGF79904.1 - 1.3e-37 128.7 0.1 1.8e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase RNAse_A_bac PF18431.1 EGF79906.1 - 0.07 14.1 0.5 0.07 14.1 0.5 3.1 3 0 0 3 3 3 0 Bacterial CdiA-CT RNAse A domain DUF2025 PF09634.10 EGF79906.1 - 0.14 12.2 1.0 2.8 8.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2025) Latarcin PF10279.9 EGF79906.1 - 0.82 10.1 4.2 0.97 9.9 1.8 2.4 2 0 0 2 2 2 0 Latarcin precursor Rx_N PF18052.1 EGF79906.1 - 8.2 6.8 17.7 0.29 11.4 0.2 5.1 5 0 0 5 5 5 0 Rx N-terminal domain UAA PF08449.11 EGF79907.1 - 5.9e-50 170.2 19.8 6.7e-50 170.0 19.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGF79907.1 - 1.1e-05 25.6 26.7 0.00041 20.5 9.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGF79907.1 - 3.6 6.8 18.9 25 4.1 18.9 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family Pkinase PF00069.25 EGF79908.1 - 1.7e-73 247.2 0.1 2.7e-73 246.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF79908.1 - 4.5e-51 173.6 0.0 8.7e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGF79908.1 - 3.3e-23 81.8 0.3 1.1e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 EGF79908.1 - 5.1e-12 46.2 1.1 1.1e-11 45.2 1.1 1.5 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 EGF79908.1 - 5e-07 28.8 0.1 7.9e-07 28.2 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF79908.1 - 7e-07 28.8 0.0 5.6e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGF79908.1 - 0.00027 20.0 0.5 0.00071 18.6 0.5 1.6 1 1 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 EGF79908.1 - 0.0009 19.6 0.9 0.028 14.8 0.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 EGF79908.1 - 0.0031 17.5 0.3 0.021 14.7 0.2 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGF79908.1 - 0.013 14.6 0.3 0.021 13.9 0.3 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGF79908.1 - 0.13 11.6 0.2 0.29 10.5 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hus1 PF04005.12 EGF79909.1 - 6.2e-64 215.9 0.2 7.5e-64 215.6 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Tubulin PF00091.25 EGF79910.1 - 2.8e-25 89.7 0.0 4.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 EGF79910.1 - 0.0016 17.7 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like NOP5NT PF08156.13 EGF79910.1 - 0.083 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 NOP5NT (NUC127) domain Gelsolin PF00626.22 EGF79911.1 - 5.2e-39 132.0 0.0 3.6e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat CheR_N PF03705.15 EGF79913.1 - 0.074 12.8 0.6 9.4 6.0 0.0 2.7 3 0 0 3 3 3 0 CheR methyltransferase, all-alpha domain FapA PF03961.13 EGF79914.1 - 0.0037 15.9 2.1 0.0053 15.4 2.1 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A BLOC1_2 PF10046.9 EGF79914.1 - 0.0044 17.3 2.5 2.5 8.4 0.0 2.2 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 EGF79914.1 - 0.0087 16.3 0.6 0.014 15.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) BicD PF09730.9 EGF79914.1 - 0.021 13.2 1.0 0.028 12.9 1.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Prp19 PF08606.11 EGF79914.1 - 0.024 14.6 0.1 0.058 13.4 0.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like IFT57 PF10498.9 EGF79914.1 - 0.03 13.3 2.3 1 8.2 0.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DivIC PF04977.15 EGF79914.1 - 0.033 14.0 5.7 0.088 12.6 1.7 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 EGF79914.1 - 0.086 13.4 6.2 0.12 12.9 6.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region CdvA PF18822.1 EGF79914.1 - 0.093 12.6 5.0 1.6 8.6 0.5 2.1 2 0 0 2 2 2 0 CdvA-like coiled-coil domain SlyX PF04102.12 EGF79914.1 - 0.094 13.3 2.5 1.3 9.7 0.3 2.2 2 0 0 2 2 2 0 SlyX Prefoldin_2 PF01920.20 EGF79914.1 - 0.16 11.9 10.2 1.4 8.9 10.2 2.0 1 1 0 1 1 1 0 Prefoldin subunit DUF4599 PF15371.6 EGF79914.1 - 0.37 11.3 1.8 0.64 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Seryl_tRNA_N PF02403.22 EGF79914.1 - 0.45 10.8 5.3 9.3 6.5 1.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 EGF79914.1 - 1.1 9.6 7.4 0.23 11.8 2.4 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 EGF79914.1 - 2 7.6 3.7 4.9 6.3 3.6 1.5 1 1 0 1 1 1 0 TMPIT-like protein Uds1 PF15456.6 EGF79914.1 - 5.2 7.3 7.0 14 5.9 0.5 2.2 2 0 0 2 2 2 0 Up-regulated During Septation DUF5427 PF10310.9 EGF79916.1 - 0.0059 15.6 0.6 0.0059 15.6 0.6 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF5427) DUF573 PF04504.14 EGF79916.1 - 0.0096 16.6 3.2 0.046 14.4 2.2 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF573 YkyA PF10368.9 EGF79916.1 - 0.024 14.3 5.6 0.036 13.8 5.6 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Spc7 PF08317.11 EGF79916.1 - 0.025 13.5 4.0 0.036 12.9 4.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EGF79916.1 - 0.028 14.2 9.7 0.067 13.0 9.6 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 ISG65-75 PF11727.8 EGF79916.1 - 0.049 12.9 0.7 0.076 12.2 0.7 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4961 PF16328.5 EGF79916.1 - 0.049 12.9 0.1 0.069 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) CLZ PF16526.5 EGF79916.1 - 0.061 13.7 2.1 0.061 13.7 2.1 1.8 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myb_DNA-bind_4 PF13837.6 EGF79916.1 - 0.084 13.3 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF16 PF01519.16 EGF79916.1 - 0.092 13.2 8.2 1.3 9.6 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Nup_retrotrp_bd PF10599.9 EGF79916.1 - 0.11 13.1 6.0 0.18 12.5 6.0 1.2 1 0 0 1 1 1 0 Retro-transposon transporting motif ATG16 PF08614.11 EGF79916.1 - 0.18 12.0 8.1 0.037 14.3 4.1 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EGF79916.1 - 0.23 11.6 6.6 0.35 11.0 6.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 EGF79916.1 - 4.3 7.5 8.5 11 6.2 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor GHMP_kinases_N PF00288.26 EGF79917.1 - 2.7e-15 56.3 0.3 6.7e-15 55.1 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGF79917.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 1.9 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EGF79917.1 - 0.0053 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature FERM_f0 PF16511.5 EGF79918.1 - 1.4e-14 54.1 0.5 0.0011 19.3 0.0 4.6 4 1 0 4 4 4 4 N-terminal or F0 domain of Talin-head FERM Rad60-SLD PF11976.8 EGF79918.1 - 0.00011 21.9 0.0 0.67 9.8 0.0 5.0 5 0 0 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like FERM_N PF09379.10 EGF79918.1 - 0.14 12.2 0.5 9 6.3 0.0 3.6 4 0 0 4 4 4 0 FERM N-terminal domain Gtr1_RagA PF04670.12 EGF79919.1 - 3.6e-63 213.0 0.0 4.5e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGF79919.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGF79919.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGF79919.1 - 0.0016 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EGF79919.1 - 0.0039 17.6 0.0 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGF79919.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EGF79919.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Bunya_NS-S PF01104.17 EGF79919.1 - 0.14 12.0 0.3 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s FtsK_SpoIIIE PF01580.18 EGF79919.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family RRM_1 PF00076.22 EGF79920.1 - 1e-42 143.8 0.0 9e-15 54.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF79920.1 - 0.0052 16.9 0.1 1.1 9.4 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGF79920.1 - 0.0076 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGF79920.1 - 0.074 12.9 0.0 2.5 8.0 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EGF79920.1 - 0.1 12.4 0.0 4.3 7.1 0.0 2.3 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RNA_Me_trans PF04252.13 EGF79921.1 - 4.9e-67 225.4 0.0 5.6e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Topoisom_I PF01028.20 EGF79922.1 - 3e-98 327.7 3.2 3e-98 327.7 3.2 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGF79922.1 - 7.5e-91 303.4 2.3 8e-91 303.3 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGF79922.1 - 1.2e-32 111.7 1.0 1.2e-32 111.7 1.0 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain Ndc1_Nup PF09531.10 EGF79922.1 - 0.5 9.0 6.6 0.95 8.1 6.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 EGF79923.1 - 7.2e-10 39.3 14.9 0.19 12.7 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79923.1 - 7.8e-08 32.5 0.0 0.058 13.7 0.0 3.9 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF79923.1 - 0.02 13.9 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 EGF79923.1 - 0.044 13.1 0.0 0.066 12.5 0.0 1.3 1 1 0 1 1 1 0 CPSF A subunit region UFD1 PF03152.14 EGF79924.1 - 2.1e-33 115.2 0.0 3.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TauD PF02668.16 EGF79924.1 - 0.2 11.4 0.1 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family RNA_pol_Rpc34 PF05158.12 EGF79925.1 - 1.1e-70 238.7 0.7 1.2e-69 235.2 0.7 2.0 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 EGF79925.1 - 0.014 16.0 0.1 0.11 13.2 0.0 2.1 2 0 0 2 2 2 0 Replication protein A C terminal HxlR PF01638.17 EGF79925.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix MarR PF01047.22 EGF79925.1 - 0.095 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 MarR family B-block_TFIIIC PF04182.12 EGF79925.1 - 0.23 11.7 1.0 0.59 10.3 0.3 1.9 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Erg28 PF03694.13 EGF79926.1 - 6.7e-37 126.2 1.3 8.9e-37 125.8 1.3 1.1 1 0 0 1 1 1 1 Erg28 like protein Adeno_E3_CR2 PF02439.15 EGF79927.1 - 0.0058 16.4 0.8 0.01 15.6 0.8 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 CD99L2 PF12301.8 EGF79927.1 - 0.0061 16.9 0.1 0.045 14.0 0.0 2.0 2 0 0 2 2 2 1 CD99 antigen like protein 2 MGC-24 PF05283.11 EGF79927.1 - 0.0087 16.5 0.3 0.0087 16.5 0.3 1.9 3 0 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1180 PF06679.12 EGF79927.1 - 0.077 13.4 0.8 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CoatB PF10389.9 EGF79927.1 - 0.085 12.7 0.8 0.16 11.9 0.8 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B TMEM154 PF15102.6 EGF79927.1 - 0.097 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 EGF79927.1 - 0.16 11.9 0.2 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 EGF79927.1 - 0.19 11.8 0.3 0.41 10.8 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Otopetrin PF03189.13 EGF79927.1 - 0.21 10.4 0.0 0.48 9.2 0.0 1.5 2 0 0 2 2 2 0 Otopetrin Aa_trans PF01490.18 EGF79928.1 - 9.6e-09 34.4 3.6 1e-08 34.3 3.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HEAT_2 PF13646.6 EGF79929.1 - 3.2e-31 107.6 0.3 4.4e-15 55.8 0.1 3.8 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EGF79929.1 - 5.4e-26 88.6 0.0 1.6e-05 25.1 0.1 7.2 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGF79929.1 - 1.5e-14 52.9 0.7 0.11 12.8 0.0 6.0 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 EGF79929.1 - 1.6e-11 44.4 0.1 0.0071 16.8 0.0 5.2 4 1 1 5 5 5 3 HEAT-like repeat Arm PF00514.23 EGF79929.1 - 3.4e-05 23.7 0.0 0.088 12.9 0.0 3.1 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGF79929.1 - 0.00085 19.4 0.0 3.1 7.8 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 EGF79929.1 - 0.014 15.7 0.2 14 6.1 0.0 4.1 3 2 1 4 4 4 0 TAF6 C-terminal HEAT repeat domain Vitellogenin_N PF01347.22 EGF79929.1 - 0.047 12.1 1.5 4.8 5.5 0.0 2.8 1 1 0 3 3 3 0 Lipoprotein amino terminal region Aconitase_B_N PF11791.8 EGF79929.1 - 0.058 13.5 0.0 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Aconitate B N-terminal domain DUF438 PF04282.13 EGF79929.1 - 0.16 12.0 0.4 0.71 9.9 0.0 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF438) COQ7 PF03232.13 EGF79930.1 - 2.6e-73 245.4 0.0 3e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.6 EGF79930.1 - 0.015 15.5 0.0 0.48 10.6 0.0 2.2 1 1 1 2 2 2 0 Ferritin-like domain Rubrerythrin PF02915.17 EGF79930.1 - 0.032 14.6 0.0 0.095 13.1 0.0 1.8 1 1 0 1 1 1 0 Rubrerythrin Pex2_Pex12 PF04757.14 EGF79931.1 - 7.8e-33 113.9 8.9 1.1e-32 113.5 8.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EGF79931.1 - 6.6e-06 26.0 7.4 1.1e-05 25.3 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGF79931.1 - 1.4e-05 25.1 3.5 3.4e-05 23.9 3.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGF79931.1 - 0.0002 21.1 7.9 0.00032 20.5 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF79931.1 - 0.00054 19.8 7.8 0.0011 18.8 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF79931.1 - 0.0022 18.3 8.6 0.0036 17.6 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGF79931.1 - 0.0028 17.5 9.6 0.0052 16.6 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF79931.1 - 0.0075 16.1 5.7 0.014 15.3 5.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF79931.1 - 0.0081 16.2 4.7 0.021 14.8 4.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DZR PF12773.7 EGF79931.1 - 0.09 12.8 3.1 0.13 12.3 1.3 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 EGF79931.1 - 0.17 12.1 4.6 0.33 11.1 4.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EGF79931.1 - 0.24 11.1 5.9 0.44 10.2 5.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EGF79931.1 - 0.26 11.6 6.4 0.48 10.7 6.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-HIT PF04438.16 EGF79931.1 - 1.1 9.2 11.1 10 6.1 0.2 2.9 2 1 0 2 2 2 0 HIT zinc finger ETC_C1_NDUFA4 PF04800.12 EGF79932.1 - 8.8e-37 125.3 1.3 1.1e-36 124.9 1.3 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region DHC_N1 PF08385.12 EGF79933.1 - 1.9e-177 591.4 20.9 3.6e-177 590.4 10.2 3.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EGF79933.1 - 5.3e-146 485.7 0.0 2e-145 483.9 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF79933.1 - 4.7e-124 414.5 12.5 4.7e-124 414.5 12.5 3.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGF79933.1 - 2e-98 328.9 0.2 4.8e-98 327.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGF79933.1 - 6.6e-97 324.4 0.0 6.6e-97 324.4 0.0 3.4 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGF79933.1 - 4.2e-82 274.5 1.3 4.2e-82 274.5 1.3 3.6 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF79933.1 - 1.3e-70 236.6 0.9 6.3e-64 214.8 0.0 4.3 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF79933.1 - 3e-54 183.2 0.0 9.4e-54 181.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGF79933.1 - 8.5e-41 138.8 0.1 3.8e-39 133.5 0.0 3.7 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGF79933.1 - 2.8e-37 128.6 9.4 2.8e-37 128.6 9.4 2.8 3 0 0 3 3 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EGF79933.1 - 4.5e-22 78.5 0.0 4.9e-07 29.8 0.0 5.2 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGF79933.1 - 9.2e-20 70.7 0.0 8.1e-18 64.5 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGF79933.1 - 3e-16 59.7 1.5 1.9e-15 57.1 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EGF79933.1 - 8.1e-11 42.5 0.7 0.032 14.6 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF79933.1 - 1.1e-09 39.0 0.6 0.16 12.3 0.0 6.0 5 1 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 EGF79933.1 - 4.3e-07 30.3 2.7 0.33 11.2 0.0 5.0 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 EGF79933.1 - 0.00056 19.1 0.3 0.062 12.3 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGF79933.1 - 0.0029 17.0 0.4 0.13 11.6 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EGF79933.1 - 0.0048 16.6 10.6 8.2 6.1 0.0 5.0 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.6 EGF79933.1 - 0.0064 16.7 0.4 24 5.1 0.0 4.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 EGF79933.1 - 0.0064 15.5 0.3 0.023 13.6 0.1 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.26 EGF79933.1 - 0.013 15.2 0.2 3.5 7.3 0.0 3.7 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_29 PF13555.6 EGF79933.1 - 0.032 14.0 0.3 5 6.9 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGF79933.1 - 0.045 13.1 0.4 9.4 5.5 0.1 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGF79933.1 - 0.05 14.0 0.3 6.6 7.2 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 EGF79933.1 - 0.095 13.2 7.5 3 8.4 0.0 5.0 6 0 0 6 6 3 0 AAA domain AAA_19 PF13245.6 EGF79933.1 - 0.18 12.1 14.0 2.1 8.7 0.1 5.0 5 0 0 5 5 4 0 AAA domain DUF4527 PF15030.6 EGF79933.1 - 0.23 10.8 5.2 0.22 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Cut12 PF11500.8 EGF79933.1 - 0.24 11.4 2.3 3.4 7.6 0.1 2.8 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Glypican PF01153.19 EGF79934.1 - 0.0042 16.0 0.1 0.0062 15.4 0.1 1.2 1 0 0 1 1 1 1 Glypican Pribosyltran PF00156.27 EGF79935.1 - 4.7e-15 55.4 0.0 6.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1256 PF06866.11 EGF79935.1 - 0.047 13.1 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) DUF2373 PF10180.9 EGF79936.1 - 9.5e-15 54.2 2.1 9.5e-15 54.2 2.1 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) SRP_TPR_like PF17004.5 EGF79936.1 - 0.033 14.2 2.5 0.044 13.8 0.2 2.2 2 0 0 2 2 2 0 Putative TPR-like repeat CedA PF10729.9 EGF79936.1 - 0.072 12.9 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 Cell division activator CedA PPR PF01535.20 EGF79937.1 - 0.0013 18.9 0.1 0.56 10.6 0.0 4.5 4 0 0 4 4 4 1 PPR repeat TPR_12 PF13424.6 EGF79937.1 - 0.0065 16.7 0.2 0.94 9.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_long PF17177.4 EGF79937.1 - 0.024 14.0 0.0 33 3.8 0.0 3.1 2 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 EGF79937.1 - 0.025 14.4 1.0 13 5.7 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_19 PF14559.6 EGF79937.1 - 0.035 14.6 0.0 9.2 6.9 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 EGF79937.1 - 0.073 13.2 2.8 43 4.3 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_1 PF00515.28 EGF79937.1 - 0.08 12.8 2.9 6.6 6.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_Tnp_Tc5 PF03221.16 EGF79937.1 - 0.18 11.8 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF5314 PF17241.2 EGF79937.1 - 0.34 10.5 4.7 4.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5314) TPR_2 PF07719.17 EGF79937.1 - 0.38 11.0 2.4 56 4.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.6 EGF79939.1 - 1.3e-10 40.9 0.3 2e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGF79939.1 - 2.5e-06 27.0 0.1 7e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGF79939.1 - 7e-05 22.4 0.0 0.00042 19.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SP_C-Propep PF08999.10 EGF79939.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Phage_Gp23 PF10669.9 EGF79939.1 - 0.23 11.8 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) TMEM154 PF15102.6 EGF79939.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 TMEM154 protein family Peptidase_M36 PF02128.15 EGF79940.1 - 2.4e-151 504.1 0.1 2.7e-151 503.9 0.1 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) LAGLIDADG_3 PF14528.6 EGF79940.1 - 0.14 12.5 0.0 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 LAGLIDADG-like domain Peptidase_M36 PF02128.15 EGF79941.1 - 2.6e-145 484.2 0.3 3.3e-145 483.9 0.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) HD_4 PF13328.6 EGF79942.1 - 5.5e-18 65.2 0.0 7.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 EGF79942.1 - 0.00012 22.3 0.1 0.00032 20.9 0.1 1.7 1 1 0 1 1 1 1 HD domain DUF4762 PF15959.5 EGF79942.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4762) BLM10_mid PF16507.5 EGF79943.1 - 2.6e-158 528.0 3.2 2.6e-158 528.0 3.2 1.7 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGF79943.1 - 7.4e-35 118.7 0.1 1.4e-33 114.6 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) PAXNEB PF05625.11 EGF79944.1 - 5.5e-79 266.0 0.0 1.7e-78 264.3 0.0 1.6 1 1 0 1 1 1 1 PAXNEB protein ATPase PF06745.13 EGF79944.1 - 0.003 16.9 0.1 0.0048 16.3 0.1 1.3 1 0 0 1 1 1 1 KaiC DUF1265 PF06887.14 EGF79944.1 - 0.2 11.6 0.1 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Exo70 PF03081.15 EGF79945.1 - 1.5e-72 244.8 5.2 1.5e-72 244.8 5.2 2.3 1 1 1 2 2 2 1 Exo70 exocyst complex subunit HrpB7 PF09486.10 EGF79945.1 - 0.04 14.3 2.6 2.7 8.4 0.0 3.3 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF883 PF05957.13 EGF79945.1 - 0.15 12.7 0.1 1.3 9.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TipAS PF07739.13 EGF79945.1 - 0.16 12.5 5.1 8.4 7.0 0.7 3.1 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4854 PF16146.5 EGF79945.1 - 1.5 9.2 5.8 6.3 7.2 0.0 4.3 3 2 1 4 4 4 0 Domain of unknown function (DUF4854) CENP-Q PF13094.6 EGF79945.1 - 6.1 7.0 12.3 1.8 8.7 3.3 2.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CLZ PF16526.5 EGF79945.1 - 7.2 7.1 10.5 2.4 8.6 2.9 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AFP_2 PF18815.1 EGF79946.1 - 0.12 12.6 0.7 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat AFP_2 PF18815.1 EGF79947.1 - 0.12 12.6 0.7 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat CPBP PF02517.16 EGF79948.1 - 1.6e-18 66.9 3.6 1.6e-18 66.9 3.6 2.3 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF5379 PF17350.2 EGF79948.1 - 0.065 13.5 2.3 0.25 11.6 2.3 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5379) Dynein_light PF01221.18 EGF79949.1 - 6.8e-43 144.9 1.9 7.8e-43 144.7 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SAP PF02037.27 EGF79950.1 - 1.5e-09 37.4 0.7 2.5e-09 36.7 0.7 1.3 1 0 0 1 1 1 1 SAP domain SNARE_assoc PF09335.11 EGF79950.1 - 3.3e-07 30.8 0.5 3.3e-07 30.8 0.5 3.4 4 0 0 4 4 4 1 SNARE associated Golgi protein DUF3040 PF11239.8 EGF79950.1 - 0.1 12.9 0.2 15 5.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SHQ1 PF04925.15 EGF79951.1 - 5.7e-59 198.6 2.1 8.7e-59 198.0 2.1 1.3 1 0 0 1 1 1 1 SHQ1 protein Syntaxin PF00804.25 EGF79952.1 - 3.7e-43 147.6 18.9 5.8e-43 146.9 18.9 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EGF79952.1 - 2.5e-06 27.4 1.0 2.5e-06 27.4 1.0 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EGF79952.1 - 0.0001 22.6 8.0 0.0001 22.6 8.0 3.6 2 2 1 3 3 3 1 Syntaxin-like protein DUF4513 PF14983.6 EGF79952.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) DUF3018 PF11455.8 EGF79952.1 - 0.082 12.8 0.2 0.082 12.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) LAM_C PF12544.8 EGF79952.1 - 0.88 9.8 7.2 0.084 13.0 1.2 2.2 2 1 0 2 2 2 0 Lysine-2,3-aminomutase DUF948 PF06103.11 EGF79952.1 - 1.8 8.9 11.8 0.21 11.9 1.7 3.4 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_5_C PF18564.1 EGF79953.1 - 1.1e-18 67.6 0.2 2.3e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EGF79953.1 - 2.2e-17 63.4 0.1 2.9e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) HAGH_C PF16123.5 EGF79954.1 - 3.1e-16 59.6 0.0 5.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGF79954.1 - 3.1e-12 46.9 1.1 3.2e-10 40.3 1.4 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGF79954.1 - 0.00089 18.8 0.2 0.0013 18.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF79954.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Metallophos PF00149.28 EGF79955.1 - 1.3e-37 130.3 0.2 1.8e-37 129.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGF79955.1 - 0.0042 17.5 0.6 0.011 16.2 0.6 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGF79955.1 - 0.032 14.4 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 EGF79955.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain SIR2 PF02146.17 EGF79956.1 - 3.3e-65 219.3 0.0 4.7e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGF79956.1 - 0.0067 16.2 0.1 5.2 6.8 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 EGF79956.1 - 0.0084 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) BIR PF00653.21 EGF79956.1 - 0.24 12.1 2.1 0.57 10.9 2.1 1.6 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zinc_ribbon_2 PF13240.6 EGF79956.1 - 0.91 9.3 4.3 8.8 6.2 1.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF982 PF06169.12 EGF79957.1 - 0.11 12.5 1.6 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF982) FA_hydroxylase PF04116.13 EGF79958.1 - 1e-25 90.6 18.7 1e-25 90.6 18.7 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ydr279_N PF17745.1 EGF79959.1 - 1.6e-08 34.7 1.0 6.4e-08 32.7 0.0 2.3 3 0 0 3 3 3 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 EGF79959.1 - 2e-07 31.3 0.0 4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Arf PF00025.21 EGF79960.1 - 4.7e-67 224.8 0.1 5.3e-67 224.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF79960.1 - 2.4e-14 53.6 0.0 3.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGF79960.1 - 7.5e-13 48.4 0.0 9.4e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGF79960.1 - 1.3e-12 47.6 0.7 3.3e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGF79960.1 - 4.3e-12 45.8 0.0 5.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGF79960.1 - 1.5e-11 44.2 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGF79960.1 - 5.1e-09 36.2 0.0 8.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGF79960.1 - 0.0018 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGF79960.1 - 0.006 16.5 0.0 2.8 7.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGF79960.1 - 0.027 14.0 0.1 0.19 11.2 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGF79960.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.7 1 1 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 EGF79960.1 - 0.049 13.2 0.1 0.16 11.5 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 EGF79960.1 - 0.075 13.1 0.1 3.5 7.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain Sds3 PF08598.11 EGF79961.1 - 1.3e-07 31.9 0.6 1.3e-07 31.9 0.6 2.5 3 0 0 3 3 3 1 Sds3-like KdpC PF02669.15 EGF79962.1 - 0.0069 16.2 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 K+-transporting ATPase, c chain FA_desaturase PF00487.24 EGF79963.1 - 2.8e-37 129.0 16.9 4.1e-37 128.4 16.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGF79963.1 - 4.2e-10 39.6 0.1 9.5e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SOSSC PF15925.5 EGF79964.1 - 0.0002 22.6 4.1 0.017 16.4 4.1 2.5 1 1 0 1 1 1 1 SOSS complex subunit C EF-hand_7 PF13499.6 EGF79965.1 - 0.0011 19.3 0.8 0.0078 16.6 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EGF79965.1 - 0.0035 17.1 0.3 0.0095 15.8 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGF79965.1 - 0.018 14.6 0.3 0.065 12.8 0.3 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGF79965.1 - 0.03 14.3 1.1 1.9 8.6 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain CssAB PF16831.5 EGF79965.1 - 0.036 14.5 0.3 0.68 10.3 0.0 2.6 3 0 0 3 3 3 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 EF-hand_like PF09279.11 EGF79965.1 - 0.076 13.5 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Myb_DNA-bind_3 PF12776.7 EGF79966.1 - 1e-09 39.3 0.2 2.3e-09 38.1 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4148 PF13663.6 EGF79966.1 - 3.9 7.7 14.6 7.2 6.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) FHA PF00498.26 EGF79967.1 - 8.9e-10 38.8 0.1 2.5e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 EGF79967.1 - 0.00028 20.7 0.1 0.00079 19.3 0.1 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain NIBRIN_BRCT_II PF16508.5 EGF79967.1 - 0.0009 19.6 0.1 0.0061 16.9 0.0 2.5 3 0 0 3 3 3 1 Second BRCT domain on Nijmegen syndrome breakage protein LNS2 PF08235.13 EGF79968.1 - 3.7e-105 350.4 0.0 5.2e-105 349.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGF79968.1 - 6.1e-38 128.9 0.0 1.4e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EGF79968.1 - 8.1e-20 70.9 0.0 1.7e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Cpn60_TCP1 PF00118.24 EGF79969.1 - 1.9e-156 521.6 5.7 2.1e-156 521.4 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 EGF79969.1 - 0.051 12.8 0.2 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TBCA PF02970.16 EGF79970.1 - 0.0018 18.5 1.9 0.0072 16.6 0.2 2.3 2 0 0 2 2 2 1 Tubulin binding cofactor A DUF16 PF01519.16 EGF79970.1 - 0.11 12.9 1.9 4.1 7.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.6 EGF79970.1 - 0.15 11.4 1.0 0.18 11.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 EGF79970.1 - 4.2 8.1 9.0 0.89 10.2 1.8 3.0 2 2 1 3 3 3 0 SlyX RNA_pol_Rpc4 PF05132.14 EGF79971.1 - 4.3e-21 75.9 1.5 4.3e-21 75.9 1.5 2.5 2 1 0 2 2 2 1 RNA polymerase III RPC4 DUF5310 PF17237.2 EGF79971.1 - 0.091 12.6 0.3 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5310) ATG_C PF09333.11 EGF79972.1 - 1.8e-31 108.3 0.1 4.4e-31 107.1 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGF79972.1 - 0.0045 16.8 0.1 0.019 14.7 0.1 2.1 2 1 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EGF79973.1 - 4.5e-20 71.9 0.1 1.9e-19 69.9 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EGF79973.1 - 8e-05 22.4 1.6 0.00047 19.9 0.0 3.0 4 0 0 4 4 4 1 Autophagy-related protein 2 CAD motif SpoVAD PF07451.11 EGF79973.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) HSP90 PF00183.18 EGF79974.1 - 2.9e-156 521.4 3.5 4.3e-156 520.8 3.5 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGF79974.1 - 1.2e-11 45.1 0.6 2.1e-11 44.3 0.6 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGF79974.1 - 2.6e-11 43.5 0.5 6.3e-11 42.3 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HIG_1_N PF04588.13 EGF79975.1 - 9.4e-11 41.8 0.3 1.2e-10 41.4 0.3 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region WD40 PF00400.32 EGF79976.1 - 3.5e-47 157.4 19.3 4e-06 27.4 0.3 11.3 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79976.1 - 3.9e-22 78.4 0.8 3.3e-05 24.1 0.1 6.2 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF79976.1 - 5.3e-11 42.8 2.9 0.0079 16.1 0.1 4.3 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGF79976.1 - 6.6e-05 22.0 1.9 0.77 8.7 0.0 5.0 3 2 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EGF79976.1 - 0.00099 18.3 0.8 0.65 9.0 0.2 2.7 2 1 1 3 3 3 3 Coatomer WD associated region TFIIIC_delta PF12657.7 EGF79976.1 - 0.0025 17.8 1.3 2.2 8.2 0.1 3.9 3 2 2 5 5 5 2 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 EGF79976.1 - 0.0026 17.6 0.2 37 4.4 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 EGF79976.1 - 0.0078 14.6 0.0 0.59 8.4 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EGF79976.1 - 0.01 14.6 1.0 0.14 10.8 0.1 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EGF79976.1 - 0.039 13.3 0.7 1.1 8.5 0.0 3.3 3 2 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 EGF79976.1 - 0.045 14.2 4.4 0.21 12.1 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain CPSF_A PF03178.15 EGF79976.1 - 0.15 11.4 0.2 0.59 9.4 0.0 2.2 2 1 0 2 2 2 0 CPSF A subunit region PAC3 PF10178.9 EGF79977.1 - 5.2e-13 49.0 0.3 1.6e-12 47.4 0.1 1.9 2 1 0 2 2 2 1 Proteasome assembly chaperone 3 Flg_hook PF02120.16 EGF79977.1 - 0.025 14.5 1.3 0.027 14.3 0.2 1.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK TAP42 PF04177.12 EGF79978.1 - 8.8e-86 287.9 7.5 1e-85 287.7 7.5 1.0 1 0 0 1 1 1 1 TAP42-like family gag-asp_proteas PF13975.6 EGF79979.1 - 0.027 15.0 0.0 0.068 13.7 0.0 1.6 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1264 PF06884.11 EGF79979.1 - 0.085 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) YfkB PF08756.10 EGF79979.1 - 0.13 12.0 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 YfkB-like domain UDPGP PF01704.18 EGF79980.1 - 7.5e-196 650.7 0.2 8.6e-196 650.5 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fibrinogen_BP PF08017.11 EGF79981.1 - 0.00021 19.8 1.5 0.00037 19.1 1.5 1.3 1 0 0 1 1 1 1 Fibrinogen binding protein DUF2981 PF11200.8 EGF79981.1 - 2.2 7.9 13.8 0.25 11.1 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Dynactin PF12455.8 EGF79982.1 - 9.5e-26 90.7 10.6 9.5e-26 90.7 10.6 3.7 3 1 0 3 3 3 2 Dynein associated protein CAP_GLY PF01302.25 EGF79982.1 - 4.7e-21 74.6 0.1 7.8e-21 73.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain CENP-F_leu_zip PF10473.9 EGF79982.1 - 0.0042 17.1 9.4 0.0042 17.1 9.4 5.6 6 1 1 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 EGF79982.1 - 0.59 9.9 12.2 0.09 12.6 6.0 3.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DASH_Dad4 PF08650.10 EGF79982.1 - 2.2 8.3 11.7 5.3 7.1 0.4 4.3 3 0 0 3 3 3 0 DASH complex subunit Dad4 WD40 PF00400.32 EGF79983.1 - 1.9e-06 28.5 5.7 0.0015 19.3 0.3 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF79983.1 - 0.0067 16.7 0.0 0.061 13.6 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGF79983.1 - 0.016 14.0 0.0 0.034 12.9 0.0 1.6 1 0 0 1 1 1 0 Nup133 N terminal like TPR_1 PF00515.28 EGF79985.1 - 5.7e-15 54.4 1.9 2.1e-05 24.1 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGF79985.1 - 1.6e-11 43.4 4.0 0.00079 19.4 0.0 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF79985.1 - 3.6e-05 24.0 1.4 0.62 10.4 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF79985.1 - 4.3e-05 23.2 0.8 0.22 11.6 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF79985.1 - 9e-05 22.4 0.6 1.6 9.1 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF79985.1 - 0.0023 17.6 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 EGF79985.1 - 0.0032 17.6 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF79985.1 - 0.0045 17.6 0.2 2.2 9.0 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF79985.1 - 0.014 16.1 0.0 1.1 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1748 PF08520.10 EGF79986.1 - 3.2e-17 62.2 0.0 3.6e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Velvet PF11754.8 EGF79987.1 - 2.4e-43 148.9 0.2 3.8e-43 148.2 0.2 1.3 1 0 0 1 1 1 1 Velvet factor Pro_isomerase PF00160.21 EGF79988.1 - 1.4e-46 158.6 0.2 1.6e-46 158.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MAP65_ASE1 PF03999.12 EGF79989.1 - 1.6e-26 93.2 24.1 3.6e-26 92.0 24.1 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Wx5_PLAF3D7 PF09688.10 EGF79989.1 - 0.042 13.9 3.8 0.14 12.1 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Tma16 PF11176.8 EGF79990.1 - 2.3e-36 124.9 0.2 2.6e-36 124.7 0.2 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 HTH_5 PF01022.20 EGF79990.1 - 0.12 12.3 0.1 12 5.8 0.1 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, arsR family I-set PF07679.16 EGF79991.1 - 0.08 13.0 0.0 43 4.3 0.0 3.6 3 0 0 3 3 3 0 Immunoglobulin I-set domain ENTH PF01417.20 EGF79992.1 - 1.9e-41 141.0 0.2 2.7e-41 140.5 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGF79992.1 - 0.0076 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 EGF79992.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain Nnf1 PF03980.14 EGF79993.1 - 5.4e-18 65.4 4.5 7.5e-18 64.9 4.5 1.2 1 0 0 1 1 1 1 Nnf1 RBM39linker PF15519.6 EGF79993.1 - 0.31 12.1 2.8 1.3 10.1 0.2 2.6 1 1 1 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein RabGAP-TBC PF00566.18 EGF79994.1 - 2.3e-14 53.6 0.7 4.9e-13 49.2 0.2 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Clathrin PF00637.20 EGF79995.1 - 4.8e-197 645.8 34.1 9.1e-34 116.4 0.3 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EGF79995.1 - 6.3e-41 136.7 5.1 1.2e-07 31.7 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EGF79995.1 - 6.1e-31 106.1 0.0 5.5e-30 103.1 0.0 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 EGF79995.1 - 3.8e-10 39.0 0.6 9.4e-10 37.7 0.6 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 EGF79995.1 - 1.8e-08 33.9 1.8 0.00026 20.2 0.0 4.1 4 1 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 EGF79995.1 - 0.0019 17.9 3.0 3.1 7.8 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF79995.1 - 0.0043 17.7 3.6 44 5.3 0.1 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF79995.1 - 0.012 15.7 5.6 10 6.6 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF79995.1 - 0.033 14.2 10.3 3.2 8.0 0.1 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF79995.1 - 0.051 14.1 4.7 28 5.3 0.1 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF79995.1 - 0.059 13.5 7.7 12 6.3 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DNA_methylase PF00145.17 EGF79997.1 - 9.4e-31 107.4 0.0 1.9e-27 96.5 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Met_10 PF02475.16 EGF79997.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DUF5428 PF17493.2 EGF79998.1 - 0.6 10.6 2.9 0.44 11.0 0.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5428) Npa1 PF11707.8 EGF79999.1 - 0.0018 17.7 0.1 0.0037 16.7 0.1 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal PPR PF01535.20 EGF79999.1 - 0.011 16.0 3.6 15 6.1 0.0 6.2 7 0 0 7 7 7 0 PPR repeat SPOB_a PF14689.6 EGF79999.1 - 0.018 14.7 2.1 35 4.2 0.0 4.8 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain PPR_2 PF13041.6 EGF79999.1 - 0.11 12.7 0.1 66 3.8 0.0 4.1 3 1 1 4 4 4 0 PPR repeat family DUF1084 PF06454.11 EGF80000.1 - 0.00026 20.5 12.7 0.00043 19.8 12.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.13 EGF80000.1 - 0.085 13.2 7.8 0.22 11.9 7.8 1.7 1 0 0 1 1 1 0 EGF-like domain UPF0223 PF05256.12 EGF80001.1 - 0.023 15.0 5.5 0.17 12.2 1.6 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0223) CTXphi_pIII-N1 PF16710.5 EGF80001.1 - 0.15 12.2 0.2 2.3 8.4 0.0 2.1 2 0 0 2 2 2 0 N-terminal N1 domain of Vibrio phage CTXphi pIII CCDC106 PF15794.5 EGF80001.1 - 9.5 5.9 11.4 4.7 6.8 4.5 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 p450 PF00067.22 EGF80002.1 - 4.6e-81 272.9 1.6 5.8e-81 272.6 1.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 EGF80003.1 - 1.5e-26 93.6 0.0 2.2e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGF80003.1 - 1.6e-13 50.5 16.4 1.6e-13 50.5 16.4 2.0 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 EGF80003.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGF80003.1 - 0.00088 19.7 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EGF80003.1 - 0.006 15.7 14.2 0.019 14.1 14.1 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_30 PF13604.6 EGF80003.1 - 0.021 14.6 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGF80003.1 - 0.025 14.3 0.3 0.061 13.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGF80003.1 - 0.03 13.9 0.2 0.15 11.6 0.3 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGF80003.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 EGF80003.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGF80003.1 - 0.074 12.8 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF80003.1 - 0.18 12.1 0.1 0.64 10.3 0.2 1.8 2 0 0 2 2 1 0 AAA domain DUF1681 PF07933.14 EGF80004.1 - 1.1e-45 155.0 0.0 1.2e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) MBOAT PF03062.19 EGF80005.1 - 2.9e-13 49.9 23.3 2.9e-13 49.9 23.3 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3439 PF11921.8 EGF80005.1 - 2.2 8.2 14.2 0.3 11.1 6.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PNK3P PF08645.11 EGF80006.1 - 2.4e-39 134.6 0.0 5.9e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGF80006.1 - 7.3e-14 52.1 0.0 3.1e-11 43.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGF80006.1 - 6.3e-05 22.6 0.5 0.014 14.8 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGF80006.1 - 0.011 15.0 0.0 5.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin UDPG_MGDP_dh_N PF03721.14 EGF80006.1 - 0.019 14.5 1.4 0.053 13.1 0.1 2.2 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Hydrolase_6 PF13344.6 EGF80006.1 - 0.024 14.8 0.1 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 EGF80006.1 - 0.072 13.5 0.1 0.39 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGF80006.1 - 0.11 12.3 0.8 19 5.1 0.1 2.7 1 1 1 2 2 2 0 P-loop containing region of AAA domain Utp12 PF04003.12 EGF80007.1 - 4.8e-18 65.4 2.5 9.1e-18 64.5 2.5 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 EGF80007.1 - 4.8e-06 27.2 0.4 0.053 14.4 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80007.1 - 0.0094 16.2 0.0 2.8 8.3 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MCM PF00493.23 EGF80008.1 - 9.8e-94 312.6 0.1 1.7e-93 311.8 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF80008.1 - 2.8e-31 108.0 0.0 5.3e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGF80008.1 - 1.3e-22 80.0 1.0 2.7e-22 79.0 0.3 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGF80008.1 - 1.1e-12 48.4 0.1 4.1e-12 46.6 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGF80008.1 - 1.2e-08 34.6 0.2 1.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGF80008.1 - 0.0086 15.8 0.0 0.045 13.5 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGF80008.1 - 0.0098 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EGF80008.1 - 0.04 13.7 0.0 5.2 6.8 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 EGF80008.1 - 0.052 14.0 0.1 0.16 12.4 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGF80008.1 - 0.064 13.3 0.3 0.67 9.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) SPG48 PF14764.6 EGF80009.1 - 0.065 13.7 0.0 0.31 11.5 0.0 2.1 2 1 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking CotH PF08757.11 EGF80009.1 - 0.23 10.9 0.0 0.3 10.6 0.0 1.1 1 0 0 1 1 1 0 CotH kinase protein DUF3535 PF12054.8 EGF80011.1 - 2.1e-82 277.7 2.3 1.1e-79 268.7 0.1 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGF80011.1 - 2e-59 201.1 0.0 4.2e-59 200.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF80011.1 - 6.8e-14 52.1 0.0 1.7e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGF80011.1 - 1.4e-12 46.7 16.3 2.8 8.4 0.1 11.2 11 1 1 12 12 12 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EGF80011.1 - 0.0002 21.9 0.9 3 8.5 0.0 4.4 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGF80011.1 - 0.00046 20.5 2.8 0.24 11.8 0.1 5.0 4 0 0 4 4 4 1 HEAT repeats Tir_receptor_N PF07490.11 EGF80011.1 - 0.016 15.1 0.8 0.05 13.4 0.3 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus DAG_kinase_N PF14513.6 EGF80011.1 - 0.12 12.6 0.2 0.43 10.8 0.2 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF383 PF04063.14 EGF80011.1 - 0.12 12.0 0.2 4.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF383) HEAT_EZ PF13513.6 EGF80011.1 - 0.14 12.7 16.6 62 4.3 0.0 8.6 9 1 1 10 10 9 0 HEAT-like repeat TAF6_C PF07571.13 EGF80011.1 - 0.23 11.8 1.0 3.4 8.1 0.0 3.5 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain HLH PF00010.26 EGF80012.1 - 5.6e-06 26.2 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FGGY_N PF00370.21 EGF80013.1 - 1.3e-71 241.0 0.2 1.8e-71 240.6 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGF80013.1 - 1.9e-53 181.2 2.8 2.9e-53 180.5 1.6 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain bZIP_1 PF00170.21 EGF80014.1 - 1.3e-05 25.2 6.7 2.5e-05 24.3 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGF80014.1 - 3.3e-05 23.9 8.1 6e-05 23.1 8.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGF80014.1 - 0.039 14.5 4.0 0.095 13.2 4.0 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF724 PF05266.14 EGF80014.1 - 0.22 11.3 2.1 0.37 10.6 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Asp PF00026.23 EGF80015.1 - 3.9e-60 203.9 1.0 4.5e-60 203.7 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF80015.1 - 2e-11 44.4 0.1 2.3e-07 31.2 0.1 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF80015.1 - 6.6e-06 26.0 0.4 6.7e-05 22.7 0.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF80015.1 - 0.00033 21.3 0.6 0.11 13.2 0.1 2.8 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGF80015.1 - 0.06 13.9 0.4 19 5.9 0.1 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease PEGA PF08308.11 EGF80015.1 - 0.16 11.9 1.2 0.43 10.5 0.0 2.2 3 0 0 3 3 3 0 PEGA domain NOG1_N PF17835.1 EGF80016.1 - 7.9e-53 178.7 1.5 7.9e-53 178.7 1.5 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EGF80016.1 - 3.4e-28 97.4 1.6 7.6e-28 96.3 1.6 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EGF80016.1 - 1.4e-27 95.3 0.1 1.4e-27 95.3 0.1 2.2 3 0 0 3 3 3 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EGF80016.1 - 1.3e-18 67.1 0.0 3.2e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF80016.1 - 4.6e-10 39.2 0.0 1.1e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 EGF80016.1 - 9.4e-05 22.1 0.0 0.00021 20.9 0.0 1.6 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EGF80016.1 - 0.0013 18.7 0.9 0.69 9.8 0.0 3.4 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EGF80016.1 - 0.003 17.6 0.0 3.5 7.7 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 EGF80016.1 - 0.0063 16.7 0.0 0.069 13.4 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGF80016.1 - 0.016 14.7 0.0 0.049 13.1 0.0 1.9 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 EGF80016.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 EGF80016.1 - 0.072 13.5 0.1 0.79 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain LPMO_10 PF03067.15 EGF80017.1 - 3e-06 28.0 0.2 3e-06 28.0 0.2 3.5 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ABC_tran PF00005.27 EGF80018.1 - 4.7e-53 179.4 0.0 1.1e-26 94.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGF80018.1 - 1.7e-52 178.7 40.7 1.5e-31 110.0 17.1 3.3 2 2 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGF80018.1 - 5.3e-10 39.1 0.1 0.0015 18.0 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGF80018.1 - 1.5e-07 32.1 1.0 0.00014 22.4 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGF80018.1 - 8.4e-06 25.4 0.2 0.034 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF80018.1 - 1.1e-05 25.5 2.7 0.12 12.2 0.0 4.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGF80018.1 - 3.8e-05 22.9 0.0 0.0074 15.4 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EGF80018.1 - 0.00036 20.5 0.6 0.23 11.3 0.1 3.0 2 1 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 EGF80018.1 - 0.0019 18.3 1.3 0.9 9.6 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 EGF80018.1 - 0.0021 18.1 1.1 1.5 8.9 0.1 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGF80018.1 - 0.0036 17.0 0.4 4 7.1 0.0 3.2 4 0 0 4 4 3 1 IstB-like ATP binding protein SbcCD_C PF13558.6 EGF80018.1 - 0.0055 16.9 0.3 1.2 9.4 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EGF80018.1 - 0.0079 16.6 1.0 0.89 9.9 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 EGF80018.1 - 0.012 15.3 0.0 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGF80018.1 - 0.013 15.8 2.3 1.1 9.5 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGF80018.1 - 0.052 14.0 0.6 1.9 8.9 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGF80018.1 - 0.058 13.1 0.2 0.93 9.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.21 EGF80018.1 - 0.081 12.6 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase NACHT PF05729.12 EGF80018.1 - 0.096 12.6 0.9 0.58 10.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 EGF80018.1 - 0.13 12.1 1.4 4 7.2 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EGF80018.1 - 0.13 11.8 0.2 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGF80018.1 - 0.15 11.6 3.5 0.14 11.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EGF80018.1 - 0.18 11.0 2.9 7.5 5.7 1.3 3.2 2 1 0 2 2 2 0 NB-ARC domain RAI16-like PF10257.9 EGF80019.1 - 4.7e-44 150.7 6.6 6.4e-44 150.3 6.6 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Polo_box_2 PF18531.1 EGF80019.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Polo box domain Paf1 PF03985.13 EGF80020.1 - 2.3e-67 227.9 5.0 2.5e-67 227.7 5.0 1.0 1 0 0 1 1 1 1 Paf1 Glyco_hydro_108 PF05838.12 EGF80020.1 - 0.031 14.7 0.0 0.075 13.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 108 JAB PF01398.21 EGF80021.1 - 4.7e-08 33.0 0.3 1.2e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MutS_V PF00488.21 EGF80022.1 - 3.6e-58 196.7 0.7 6.3e-58 195.9 0.7 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGF80022.1 - 2.1e-19 70.5 2.0 1.2e-17 64.7 2.0 2.5 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGF80022.1 - 9.6e-08 32.3 0.2 2.6e-07 30.9 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGF80022.1 - 2.6e-07 31.0 0.0 1.2e-06 28.9 0.0 2.1 1 1 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 EGF80022.1 - 0.016 15.2 0.0 0.052 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF80022.1 - 0.028 14.1 0.0 0.07 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGF80022.1 - 0.033 14.7 1.8 0.16 12.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EGF80022.1 - 0.089 12.4 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyridox_oxase_2 PF12766.7 EGF80023.1 - 0.0067 17.0 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ank_2 PF12796.7 EGF80024.1 - 0.0056 17.2 1.7 16 6.2 0.1 4.5 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF80024.1 - 0.011 16.3 2.8 53 4.6 0.0 4.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF89 PF01937.19 EGF80024.1 - 0.074 12.0 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF89 RNA_pol_N PF01194.17 EGF80025.1 - 8.8e-31 106.0 0.2 9.9e-31 105.8 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit HSP70 PF00012.20 EGF80026.1 - 2.8e-107 359.4 6.4 3.1e-107 359.2 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF80026.1 - 1.2e-06 27.6 0.0 5.6e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 EGF80026.1 - 0.003 16.2 0.0 0.054 12.1 0.1 2.5 2 1 1 3 3 3 1 Actin ClpS PF02617.17 EGF80026.1 - 0.052 13.3 0.1 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS FGGY_C PF02782.16 EGF80026.1 - 0.068 12.9 0.2 0.37 10.5 0.0 2.4 3 1 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain DUF348 PF03990.14 EGF80026.1 - 0.092 12.5 0.4 0.45 10.3 0.0 2.3 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Sulfate_transp PF00916.20 EGF80027.1 - 1.5e-56 191.8 21.1 2.4e-34 118.7 5.7 3.4 3 1 0 3 3 3 3 Sulfate permease family DUF2315 PF10231.9 EGF80028.1 - 1.2e-23 83.5 0.5 1.8e-23 83.0 0.5 1.2 1 0 0 1 1 1 1 Apoptogenic protein 1 DUF3685 PF12452.8 EGF80028.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) Aa_trans PF01490.18 EGF80029.1 - 1.9e-50 171.8 32.6 2.3e-50 171.5 32.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5464 PF17552.2 EGF80029.1 - 0.63 10.3 6.0 3 8.2 6.0 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5464) tRNA-synt_2b PF00587.25 EGF80030.1 - 1.7e-19 70.5 0.0 4.9e-18 65.7 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGF80030.1 - 0.0029 17.8 0.5 0.005 17.1 0.5 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Nup54 PF13874.6 EGF80032.1 - 5.3e-41 140.0 1.7 5.3e-41 140.0 1.7 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EGF80032.1 - 9e-08 32.9 105.0 8e-05 23.4 32.7 3.0 1 1 2 3 3 3 3 Nucleoporin FG repeat region Sec34 PF04136.15 EGF80032.1 - 0.067 13.1 0.2 0.067 13.1 0.2 2.3 2 1 0 2 2 2 0 Sec34-like family U-box PF04564.15 EGF80033.1 - 0.1 12.8 0.5 0.75 10.0 0.0 2.3 2 2 1 3 3 3 0 U-box domain DEAD PF00270.29 EGF80034.1 - 6e-20 71.7 0.0 1.5e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF80034.1 - 3.3e-16 59.6 0.1 6.9e-15 55.4 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Drc1-Sld2 PF11719.8 EGF80034.1 - 2e-08 34.2 0.8 2e-08 34.2 0.8 3.7 3 1 1 4 4 4 2 DNA replication and checkpoint protein ResIII PF04851.15 EGF80034.1 - 0.00027 21.0 0.0 0.00064 19.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MIP-T3 PF10243.9 EGF80035.1 - 2.3e-39 133.9 0.2 4.9e-39 132.8 0.2 1.6 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 EGF80035.1 - 1.3e-35 122.6 9.4 1.8e-35 122.2 7.7 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region GAS PF13851.6 EGF80035.1 - 0.036 13.4 4.6 0.066 12.5 4.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 EGF80035.1 - 0.65 10.5 5.9 16 6.0 2.6 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EGF80035.1 - 1.1 9.4 6.8 0.44 10.7 3.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATP-synt_ab PF00006.25 EGF80037.1 - 3.1e-71 239.4 0.0 4.9e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGF80037.1 - 1.8e-47 160.8 0.2 3e-47 160.1 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGF80037.1 - 2.1e-19 69.8 1.6 9.3e-19 67.7 1.6 2.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EGF80037.1 - 0.056 13.6 0.7 0.15 12.3 0.7 1.8 1 0 0 1 1 1 0 HAS barrel domain Radical_SAM_C PF16199.5 EGF80037.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain AAA_22 PF13401.6 EGF80037.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L21p PF00829.21 EGF80038.1 - 2.8e-14 53.2 0.0 3.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Snf7 PF03357.21 EGF80039.1 - 2.7e-29 102.0 18.6 3.1e-29 101.8 18.4 1.2 1 1 0 1 1 1 1 Snf7 CRR7 PF12095.8 EGF80039.1 - 0.05 14.1 0.9 0.17 12.4 0.1 2.2 2 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Evr1_Alr PF04777.13 EGF80040.1 - 4.9e-27 94.3 0.1 5.9e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family 7tm_1 PF00001.21 EGF80041.1 - 9.3e-09 35.0 9.2 1.5e-08 34.3 9.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EGF80041.1 - 5.8e-08 32.2 11.6 3.5e-07 29.7 11.6 1.8 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EGF80041.1 - 4.6e-07 29.8 4.0 4.6e-07 29.8 4.0 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGF80041.1 - 0.0002 21.4 2.3 0.00022 21.2 0.4 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3671 PF12420.8 EGF80041.1 - 3.9 7.6 6.9 5.2 7.2 1.6 3.0 3 0 0 3 3 3 0 Protein of unknown function P21-Arc PF04062.14 EGF80042.1 - 2e-77 259.2 0.0 2.3e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit WD40 PF00400.32 EGF80043.1 - 0.0043 17.9 0.0 0.99 10.4 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Mog1 PF04603.12 EGF80044.1 - 7e-15 55.6 0.6 7.5e-15 55.5 0.6 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Trs65 PF12735.7 EGF80045.1 - 9.9e-18 64.6 12.3 2.3e-14 53.5 0.1 3.3 2 1 0 3 3 3 2 TRAPP trafficking subunit Trs65 Transglut_C PF00927.22 EGF80045.1 - 0.016 15.3 0.1 0.049 13.8 0.1 1.9 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF561 PF04481.12 EGF80045.1 - 0.069 12.3 0.1 0.069 12.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dimer_Tnp_hAT PF05699.14 EGF80046.1 - 6.4e-20 70.7 0.2 7e-20 70.6 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp PF00026.23 EGF80048.1 - 4.6e-12 46.0 0.0 8.9e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80048.1 - 0.00025 20.8 0.1 0.0056 16.5 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4219 PF13961.6 EGF80050.1 - 0.00014 21.5 0.3 0.00034 20.2 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 EGF80050.1 - 0.021 14.5 0.2 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 EGF80050.1 - 0.041 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HR1 PF02185.16 EGF80051.1 - 0.027 14.6 2.2 0.072 13.2 2.2 1.8 1 0 0 1 1 1 0 Hr1 repeat PX PF00787.24 EGF80051.1 - 0.05 13.6 0.9 0.15 12.1 0.9 1.9 1 1 0 1 1 1 0 PX domain ADIP PF11559.8 EGF80051.1 - 0.063 13.4 1.0 0.063 13.4 1.0 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding CRISPR_Cas2 PF09827.9 EGF80051.1 - 0.078 13.2 0.5 0.35 11.1 0.1 2.3 2 0 0 2 2 2 0 CRISPR associated protein Cas2 DASH_Dam1 PF08653.10 EGF80051.1 - 0.096 12.5 0.0 0.4 10.5 0.0 2.2 1 1 0 1 1 1 0 DASH complex subunit Dam1 CREPT PF16566.5 EGF80051.1 - 0.17 12.1 3.7 2.7 8.2 0.1 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 EGF80051.1 - 0.27 11.3 2.7 6.3 6.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SMAP PF15477.6 EGF80051.1 - 4 8.5 8.4 0.34 11.9 0.6 2.6 3 0 0 3 3 3 0 Small acidic protein family Ribonuclease_3 PF00636.26 EGF80052.1 - 1.1e-17 64.6 0.0 3.9e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF80052.1 - 9.2e-11 42.0 0.0 1e-08 35.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like ANAPC4_WD40 PF12894.7 EGF80053.1 - 2.6e-12 46.9 0.0 0.024 14.9 0.0 5.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EGF80053.1 - 2.7e-08 33.8 28.6 0.46 10.3 0.0 10.5 7 4 3 11 11 11 3 Region in Clathrin and VPS WD40 PF00400.32 EGF80053.1 - 7.5e-08 32.9 3.0 0.39 11.7 0.1 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGF80053.1 - 7.4e-06 25.3 9.3 0.004 16.2 0.1 5.0 3 1 2 5 5 5 2 Coatomer WD associated region eIF2A PF08662.11 EGF80053.1 - 0.0018 18.2 0.1 1 9.2 0.0 4.2 4 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A TPR_6 PF13174.6 EGF80053.1 - 0.0056 17.2 9.3 9.1 7.2 0.1 7.0 6 0 0 6 6 4 1 Tetratricopeptide repeat PPR_2 PF13041.6 EGF80053.1 - 0.0091 16.2 1.6 4.9 7.4 0.0 4.6 4 0 0 4 4 3 1 PPR repeat family TPR_19 PF14559.6 EGF80053.1 - 0.012 16.1 10.0 7.3 7.2 0.0 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF80053.1 - 0.045 14.4 9.8 51 4.6 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGF80053.1 - 0.075 12.7 8.7 12 5.7 0.0 6.3 6 1 0 6 6 6 0 TPR repeat TPR_7 PF13176.6 EGF80053.1 - 0.13 12.3 19.6 7.4 6.9 0.0 8.9 11 0 0 11 11 9 0 Tetratricopeptide repeat PPR PF01535.20 EGF80053.1 - 0.54 10.6 7.8 18 5.8 0.0 6.6 6 0 0 6 6 5 0 PPR repeat TPR_14 PF13428.6 EGF80053.1 - 0.58 11.1 17.0 7.7 7.6 0.0 8.5 10 0 0 10 10 7 0 Tetratricopeptide repeat Cript PF10235.9 EGF80053.1 - 1.9 9.1 4.5 0.42 11.2 0.6 1.9 2 0 0 2 2 1 0 Microtubule-associated protein CRIPT TPR_10 PF13374.6 EGF80053.1 - 2.7 8.0 4.4 3.3 7.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80053.1 - 8.6 6.9 19.2 4.5 7.7 0.3 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF80053.1 - 10 6.2 28.3 11 6.1 0.3 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat tRNA-synt_His PF13393.6 EGF80054.1 - 3.7e-40 138.1 0.1 4.7e-39 134.5 0.1 2.1 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGF80054.1 - 3.1e-11 43.3 4.4 1.5e-09 37.9 0.5 2.4 2 0 0 2 2 2 2 Anticodon binding domain HGTP_anticodon2 PF12745.7 EGF80054.1 - 3.2e-05 23.6 0.6 6.3e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 EGF80054.1 - 0.003 17.5 0.2 0.021 14.8 0.1 2.4 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EGF80054.1 - 0.0032 16.6 1.3 0.17 10.9 0.4 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EGF80054.1 - 0.13 11.8 0.2 0.39 10.1 0.2 1.9 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2383 PF09537.10 EGF80055.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) RICTOR_N PF14664.6 EGF80056.1 - 5.7e-83 279.0 10.4 9.6e-83 278.2 7.8 2.5 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EGF80056.1 - 2.9e-29 101.6 0.1 6.6e-27 94.0 0.0 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EGF80056.1 - 3.9e-29 100.5 1.7 1.5e-25 89.0 0.1 4.3 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EGF80056.1 - 1.6e-21 76.3 6.2 1.9e-20 72.9 1.6 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 EGF80056.1 - 2.1e-05 24.9 1.8 0.062 13.8 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 EGF80056.1 - 0.00011 22.1 8.7 4.9 7.7 0.1 6.8 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 EGF80056.1 - 0.00067 18.3 3.4 1.4 7.3 0.1 3.4 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 EGF80056.1 - 0.008 16.2 0.7 2.2 8.3 0.1 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF80056.1 - 0.013 15.9 0.9 36 4.9 0.1 4.2 5 0 0 5 5 4 0 HEAT repeats HEAT_PBS PF03130.16 EGF80056.1 - 0.094 13.4 0.8 1.4 9.8 0.1 3.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 EGF80056.1 - 5.8 7.1 7.7 11 6.2 0.2 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 EGF80057.1 - 8.8e-75 251.5 0.0 1e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80057.1 - 1.5e-33 116.1 0.0 2.5e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF80057.1 - 0.00012 21.2 0.1 0.0021 17.1 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF80057.1 - 0.0053 16.1 0.2 0.091 12.1 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGF80057.1 - 0.0091 15.4 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF80057.1 - 0.17 11.8 0.4 0.39 10.6 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family GMP_PDE_delta PF05351.11 EGF80058.1 - 5.6e-48 163.0 1.3 6.5e-48 162.7 1.3 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit Aldose_epim PF01263.20 EGF80059.1 - 1.1e-23 84.0 0.3 2.3e-15 56.7 0.0 2.2 1 1 1 2 2 2 2 Aldose 1-epimerase ENTH PF01417.20 EGF80060.1 - 1.5e-46 157.5 0.2 2.8e-46 156.6 0.2 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EGF80060.1 - 9.3e-05 22.1 13.7 0.02 14.8 3.0 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 EGF80060.1 - 0.0011 18.1 0.1 0.0011 18.1 0.1 2.3 2 1 0 2 2 2 1 ANTH domain VHS PF00790.19 EGF80060.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 VHS domain eIF3_subunit PF08597.10 EGF80060.1 - 0.67 9.8 16.3 1.6 8.6 4.3 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Exo84_C PF16528.5 EGF80061.1 - 1.6e-58 197.9 1.8 2e-58 197.6 0.1 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGF80061.1 - 5.2e-14 52.1 0.4 2.1e-13 50.1 0.4 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 EGF80061.1 - 2e-05 24.5 0.9 8.1e-05 22.5 0.9 2.0 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.11 EGF80061.1 - 0.0049 17.0 2.3 0.0049 17.0 2.3 2.7 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S9 PF00326.21 EGF80062.1 - 1.7e-40 138.8 0.0 2.6e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EGF80062.1 - 1.1e-12 47.5 0.6 9.8e-12 44.4 0.2 2.0 1 1 1 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.7 EGF80062.1 - 0.0045 17.6 0.2 0.46 11.0 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family ubiquitin PF00240.23 EGF80063.1 - 2.2e-14 53.0 0.1 2.5e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGF80063.1 - 1.3e-05 24.9 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGF80063.1 - 0.0011 19.2 0.1 0.0012 19.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EGF80063.1 - 0.0052 17.2 0.1 0.024 15.1 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGF80063.1 - 0.082 13.0 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ABC_tran_CTD PF16326.5 EGF80064.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain MIT PF04212.18 EGF80065.1 - 0.036 14.1 0.0 0.37 10.9 0.0 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain CBFD_NFYB_HMF PF00808.23 EGF80066.1 - 5.3e-11 42.6 1.4 7.3e-11 42.2 1.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 4HFCP_synth PF04476.13 EGF80067.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 4-HFC-P synthase MIF4G PF02854.19 EGF80068.1 - 2.1e-36 125.6 5.6 2.5e-36 125.3 5.6 1.1 1 0 0 1 1 1 1 MIF4G domain NTR2 PF15458.6 EGF80068.1 - 0.0068 16.0 0.8 0.0068 16.0 0.8 1.6 2 0 0 2 2 2 1 Nineteen complex-related protein 2 FliG_N PF14842.6 EGF80068.1 - 0.018 15.6 1.4 1.6 9.3 0.0 3.1 3 1 0 3 3 3 0 FliG N-terminal domain DUF501 PF04417.12 EGF80068.1 - 0.15 11.8 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) W2 PF02020.18 EGF80069.1 - 0.00053 20.1 0.0 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4939 PF16297.5 EGF80069.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) TBCC PF07986.12 EGF80070.1 - 9.9e-27 93.1 2.2 1.8e-26 92.2 2.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGF80070.1 - 1.3e-13 51.4 1.5 2.8e-13 50.3 1.5 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Kinesin PF00225.23 EGF80071.1 - 0.015 14.3 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain AAA_22 PF13401.6 EGF80071.1 - 0.03 14.6 0.0 0.037 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF80071.1 - 0.05 13.1 0.4 1.4 8.4 0.1 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region Microtub_bd PF16796.5 EGF80071.1 - 0.057 13.4 0.0 0.097 12.6 0.0 1.3 1 1 0 1 1 1 0 Microtubule binding Viral_helicase1 PF01443.18 EGF80071.1 - 0.079 12.7 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 EGF80071.1 - 0.082 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 EGF80071.1 - 0.087 12.7 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 EGF80071.1 - 0.092 13.1 0.1 0.13 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EGF80071.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EGF80071.1 - 0.16 11.7 0.1 0.41 10.4 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein Laminin_I PF06008.14 EGF80073.1 - 0.058 13.1 0.4 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Laminin Domain I IFT57 PF10498.9 EGF80074.1 - 0.071 12.1 0.9 0.096 11.6 0.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tup_N PF08581.10 EGF80074.1 - 0.29 11.5 2.6 0.57 10.5 1.0 2.1 1 1 1 2 2 2 0 Tup N-terminal RHSP PF07999.11 EGF80075.1 - 0.0016 17.4 0.3 0.0095 14.8 0.3 2.0 1 1 0 1 1 1 1 Retrotransposon hot spot protein APG12 PF04110.13 EGF80075.1 - 0.11 12.9 0.8 32 5.0 0.0 3.3 4 0 0 4 4 4 0 Ubiquitin-like autophagy protein Apg12 MIF4G PF02854.19 EGF80076.1 - 5.2e-27 94.9 3.5 2.5e-26 92.6 3.5 2.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGF80076.1 - 1.1e-20 73.7 1.7 8.8e-20 70.8 0.0 3.2 3 0 0 3 3 3 1 MA3 domain Rotamase PF00639.21 EGF80076.1 - 2.9 8.9 6.4 1.7 9.7 2.2 2.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain Chorismate_bind PF00425.18 EGF80077.1 - 5.7e-98 327.6 0.0 7.1e-97 324.0 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGF80077.1 - 3.2e-32 111.7 0.0 7.7e-29 100.7 0.0 3.4 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region IGPS PF00218.21 EGF80078.1 - 6.8e-85 284.3 0.0 1.1e-84 283.6 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EGF80078.1 - 1.2e-43 149.1 0.0 2.2e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 EGF80078.1 - 2.8e-41 141.4 0.0 9.9e-33 113.5 0.0 2.4 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 EGF80078.1 - 1.5e-05 24.9 0.2 6.4e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.18 EGF80078.1 - 2.1e-05 23.8 1.2 0.02 13.9 0.3 2.3 1 1 1 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 EGF80078.1 - 0.00054 19.5 0.1 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.21 EGF80078.1 - 0.019 14.2 0.1 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Rad9 PF04139.13 EGF80080.1 - 9.4e-29 100.6 0.1 1.6e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Rad9 SMC_N PF02463.19 EGF80081.1 - 1.9e-70 236.7 0.0 3.4e-70 235.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGF80081.1 - 2.9e-20 72.7 0.0 1.3e-19 70.6 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGF80081.1 - 1.3e-14 54.7 3.8 5.4e-09 36.3 0.1 3.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF80081.1 - 3.7e-08 34.1 37.4 3.7e-08 34.1 37.4 6.3 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EGF80081.1 - 2.6e-07 30.7 48.6 8.4e-05 22.4 27.1 4.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGF80081.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4246 PF14033.6 EGF80082.1 - 4.9e-29 101.8 0.0 6.2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) BpuSI_N PF15516.6 EGF80082.1 - 0.055 13.4 0.2 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 BpuSI N-terminal domain SbsC_C PF18058.1 EGF80083.1 - 0.003 17.8 5.0 0.003 17.8 5.0 1.7 2 0 0 2 2 2 1 SbsC C-terminal domain MF_alpha_N PF05436.11 EGF80083.1 - 0.022 14.6 0.3 0.049 13.5 0.3 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus PEPcase_2 PF14010.6 EGF80083.1 - 0.024 13.2 1.5 0.031 12.8 1.5 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase HalX PF08663.10 EGF80083.1 - 0.027 14.8 0.2 0.12 12.7 0.2 2.1 2 0 0 2 2 2 0 HalX domain WAK_assoc PF14380.6 EGF80083.1 - 0.17 12.7 0.5 0.17 12.7 0.5 2.6 3 0 0 3 3 3 0 Wall-associated receptor kinase C-terminal TMPIT PF07851.13 EGF80083.1 - 2.9 7.0 21.8 0.049 12.9 13.3 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF2730 PF10805.8 EGF80083.1 - 3.2 7.9 7.8 14 5.9 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.17 EGF80083.1 - 3.7 7.9 6.7 0.95 9.8 2.1 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Flagellin_N PF00669.20 EGF80083.1 - 6.7 6.8 10.4 0.39 10.8 1.8 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DnaJ PF00226.31 EGF80084.1 - 1.3e-16 60.5 1.6 4.2e-15 55.6 1.6 2.4 1 1 0 1 1 1 1 DnaJ domain DUF2785 PF10978.8 EGF80084.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) BORCS7 PF16088.5 EGF80085.1 - 9.1e-29 99.8 0.7 1.2e-28 99.4 0.7 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 GCIP PF13324.6 EGF80085.1 - 0.021 14.5 0.4 0.03 13.9 0.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting zf-C2H2 PF00096.26 EGF80086.1 - 2.4e-09 37.2 18.5 0.0044 17.4 4.3 4.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF80086.1 - 1.1e-07 32.0 17.4 0.015 16.1 3.7 4.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF80086.1 - 8e-06 26.0 8.5 0.014 15.7 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 EGF80086.1 - 0.0068 16.5 0.1 0.0068 16.5 0.1 3.3 4 1 1 5 5 5 1 DBF zinc finger zf-H2C2_2 PF13465.6 EGF80086.1 - 0.0069 16.8 13.8 0.12 12.9 0.6 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 EGF80086.1 - 0.013 15.9 11.1 0.14 12.6 0.2 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 EGF80086.1 - 0.032 14.9 1.0 0.032 14.9 1.0 3.1 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Importin_rep_2 PF18786.1 EGF80086.1 - 0.04 13.8 0.5 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Importin 13 repeat zf-Di19 PF05605.12 EGF80086.1 - 0.14 12.5 8.3 0.027 14.7 3.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-B_box PF00643.24 EGF80086.1 - 2.9 8.1 7.7 0.86 9.8 0.6 2.9 2 1 0 2 2 2 0 B-box zinc finger zf-C2H2_2 PF12756.7 EGF80087.1 - 0.032 14.6 0.8 0.087 13.2 0.8 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Cytochrome_C7 PF14522.6 EGF80087.1 - 0.19 11.8 5.8 1.6 8.8 3.1 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c AAA_14 PF13173.6 EGF80088.1 - 4.8e-05 23.4 0.0 0.29 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain DNA_pol_B_2 PF03175.13 EGF80089.1 - 2.2e-05 23.5 0.1 5.6e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF918 PF06033.11 EGF80089.1 - 0.0039 17.2 0.1 0.0071 16.4 0.1 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) IstB_IS21 PF01695.17 EGF80090.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Dus PF01207.17 EGF80092.1 - 3.2e-52 177.5 0.0 5e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) HABP4_PAI-RBP1 PF04774.15 EGF80094.1 - 0.00036 21.3 0.2 0.00044 21.1 0.2 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Tropomyosin_1 PF12718.7 EGF80095.1 - 1.4e-24 86.9 36.4 1.7e-24 86.6 36.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EGF80095.1 - 3.9e-09 36.2 37.3 0.0005 19.5 23.1 2.7 1 1 2 3 3 3 3 Tropomyosin CALCOCO1 PF07888.11 EGF80095.1 - 0.068 12.0 30.4 0.025 13.5 13.5 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 EGF80095.1 - 0.14 12.2 37.0 0.41 10.7 27.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 EGF80095.1 - 0.17 11.9 37.2 0.11 12.5 14.7 3.4 1 1 4 5 5 5 0 Designed helical repeat protein 10 domain Dynamitin PF04912.14 EGF80095.1 - 0.22 10.8 23.1 0.39 10.0 23.1 1.5 1 1 0 1 1 1 0 Dynamitin TRAF_BIRC3_bd PF16673.5 EGF80095.1 - 0.59 10.0 10.8 0.064 13.0 5.3 2.3 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Fib_alpha PF08702.10 EGF80095.1 - 0.66 10.2 19.6 1.1 9.4 6.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GrpE PF01025.19 EGF80095.1 - 1.3 8.7 29.9 5.3 6.7 18.5 2.7 1 1 1 2 2 2 0 GrpE HIP1_clath_bdg PF16515.5 EGF80095.1 - 1.4 9.6 31.4 0.59 10.8 7.1 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EGF80095.1 - 2.1 8.4 18.7 1.6 8.8 4.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 EGF80095.1 - 2.2 8.8 19.5 0.098 13.1 3.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) Vps5 PF09325.10 EGF80095.1 - 2.2 7.8 25.9 0.24 10.9 9.2 2.6 1 1 0 2 2 2 0 Vps5 C terminal like Fez1 PF06818.15 EGF80095.1 - 2.4 8.6 28.5 5.5 7.4 28.5 1.6 1 1 0 1 1 1 0 Fez1 DUF4250 PF14056.6 EGF80095.1 - 3.2 7.8 7.7 2 8.4 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) CLZ PF16526.5 EGF80095.1 - 3.7 8.0 28.4 0.4 11.1 5.5 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 EGF80095.1 - 3.7 6.3 35.8 0.32 9.8 13.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 EGF80095.1 - 3.7 7.7 33.2 1 9.5 7.6 3.8 1 1 1 3 3 3 0 Centrosome localisation domain of PPC89 GAS PF13851.6 EGF80095.1 - 3.9 6.8 34.0 36 3.6 34.0 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vac_Fusion PF02346.16 EGF80095.1 - 4.3 7.0 16.2 1.4 8.6 2.6 3.5 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 APG6_N PF17675.1 EGF80095.1 - 4.4 7.8 39.6 15 6.1 23.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Bacillus_HBL PF05791.11 EGF80095.1 - 6.2 6.6 15.4 6 6.7 4.6 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.8 EGF80095.1 - 8.2 3.8 31.1 9.7 3.5 31.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RRM_1 PF00076.22 EGF80097.1 - 1.4e-16 60.1 0.0 2.9e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF80097.1 - 0.00036 20.3 0.0 0.0029 17.4 0.0 2.4 2 1 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGF80097.1 - 0.00047 19.8 0.0 0.00098 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran_CTD PF16326.5 EGF80097.1 - 0.084 13.1 0.2 0.21 11.9 0.2 1.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF1664 PF07889.12 EGF80097.1 - 0.087 12.9 1.0 0.17 11.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Helicase_C_2 PF13307.6 EGF80098.1 - 4.7e-48 163.6 0.1 7.5e-48 162.9 0.1 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGF80098.1 - 2.8e-37 128.0 2.1 5.1e-37 127.2 2.1 1.4 1 0 0 1 1 1 1 DEAD_2 OMPdecase PF00215.24 EGF80099.1 - 1.5e-71 240.6 0.0 1.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PWI PF01480.17 EGF80100.1 - 3.2e-28 97.8 0.1 6.4e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 PWI domain DNA_RNApol_7kD PF03604.13 EGF80101.1 - 1.4e-15 56.6 6.5 1.9e-15 56.2 6.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 EGF80101.1 - 0.059 13.2 0.6 0.072 12.9 0.6 1.1 1 0 0 1 1 1 0 MCM OB domain zinc_ribbon_13 PF09855.9 EGF80101.1 - 0.086 13.0 1.3 0.096 12.9 0.2 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Chorion_3 PF05387.11 EGF80101.1 - 0.14 11.8 1.8 0.15 11.7 1.8 1.0 1 0 0 1 1 1 0 Chorion family 3 ATPase_2 PF01637.18 EGF80102.1 - 5.3e-08 33.1 0.1 9.2e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGF80102.1 - 0.06 13.7 0.1 0.31 11.5 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EGF80102.1 - 0.068 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGF80102.1 - 0.091 12.8 0.4 0.72 9.9 0.4 2.2 1 1 0 1 1 1 0 AAA domain DUF4246 PF14033.6 EGF80103.1 - 5.3e-87 292.8 3.5 8.9e-83 278.9 0.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) Arm PF00514.23 EGF80103.1 - 7.9e-05 22.6 0.3 0.068 13.2 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EGF80103.1 - 0.076 12.4 0.1 2 7.7 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5578) TMPIT PF07851.13 EGF80104.1 - 0.0005 19.4 4.6 0.0005 19.4 4.6 1.4 2 0 0 2 2 2 1 TMPIT-like protein EzrA PF06160.12 EGF80104.1 - 0.079 11.1 7.9 0.12 10.5 7.9 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FapA PF03961.13 EGF80104.1 - 0.24 10.0 4.2 0.36 9.4 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A WAK_assoc PF14380.6 EGF80104.1 - 0.52 11.1 4.3 0.57 10.9 0.2 2.8 2 1 1 3 3 3 0 Wall-associated receptor kinase C-terminal PHM7_cyt PF14703.6 EGF80104.1 - 0.63 10.3 7.4 0.031 14.5 2.0 1.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OrfB_IS605 PF01385.19 EGF80104.1 - 1.2 9.4 7.5 1.4 9.2 3.1 2.4 2 0 0 2 2 2 0 Probable transposase tRNA_SAD PF07973.14 EGF80106.1 - 5.8e-07 29.5 1.3 1.2e-06 28.5 1.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EGF80106.1 - 0.0097 14.5 0.3 0.015 13.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) TSC22 PF01166.18 EGF80106.1 - 0.021 15.1 0.9 0.057 13.7 0.9 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1154 PF06631.11 EGF80106.1 - 0.16 12.0 2.8 0.33 11.0 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Fes1 PF08609.10 EGF80107.1 - 3.3e-19 69.6 1.1 1.7e-18 67.3 0.5 2.4 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 EGF80107.1 - 0.00035 21.0 0.0 0.0021 18.6 0.0 2.3 2 0 0 2 2 2 1 HEAT-like repeat V-ATPase_H_C PF11698.8 EGF80107.1 - 0.0083 16.2 0.1 0.35 11.0 0.0 2.7 2 1 1 3 3 3 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 EGF80107.1 - 0.016 15.2 0.0 0.064 13.3 0.0 2.0 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 EGF80107.1 - 0.019 15.2 0.2 0.48 10.8 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 EGF80107.1 - 0.03 14.7 0.1 0.31 11.5 0.0 2.4 1 1 1 2 2 2 0 HEAT repeats Arm PF00514.23 EGF80107.1 - 0.034 14.2 0.2 0.81 9.8 0.0 3.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Sec63 PF02889.16 EGF80109.1 - 3.1e-126 419.8 0.0 1.6e-79 266.7 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGF80109.1 - 2.1e-52 177.4 0.5 1.9e-25 89.6 0.7 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EGF80109.1 - 3.3e-23 82.6 0.0 1.1e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF80109.1 - 1.1e-16 61.1 0.0 7.1e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGF80109.1 - 7.2e-07 29.6 1.3 0.032 14.5 0.1 4.5 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EGF80109.1 - 4.9e-06 26.4 0.1 0.017 14.9 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGF80109.1 - 0.00035 20.9 3.3 0.034 14.5 0.6 3.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EGF80109.1 - 0.0027 16.8 0.0 0.63 9.0 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein Helicase_PWI PF18149.1 EGF80109.1 - 0.0056 16.8 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain PhoH PF02562.16 EGF80109.1 - 0.065 12.7 0.1 5.1 6.5 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 EGF80109.1 - 0.094 12.1 0.6 15 5.0 0.1 3.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 EGF80109.1 - 0.12 11.9 0.7 18 4.8 0.0 3.5 4 0 0 4 4 4 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 EGF80109.1 - 0.12 11.8 0.2 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NICE-3 PF07406.11 EGF80110.1 - 0.019 15.0 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 NICE-3 protein Clathrin PF00637.20 EGF80110.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Region in Clathrin and VPS Fcf1 PF04900.12 EGF80111.1 - 4.8e-32 110.3 0.1 1.4e-31 108.8 0.1 1.8 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EGF80111.1 - 1.9e-06 28.2 0.0 4.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 PIN like domain ELO PF01151.18 EGF80112.1 - 3.6e-47 161.0 24.7 4.4e-47 160.7 24.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CRT10 PF08728.10 EGF80112.1 - 0.066 11.4 0.3 0.076 11.2 0.3 1.1 1 0 0 1 1 1 0 CRT10 Kinesin PF00225.23 EGF80113.1 - 1.2e-88 297.3 3.4 1.4e-88 297.0 3.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF80113.1 - 6.3e-14 52.1 0.1 1.8e-13 50.7 0.1 1.8 1 1 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 EGF80113.1 - 0.11 12.4 1.2 0.32 10.9 1.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CUE PF02845.16 EGF80114.1 - 0.0015 18.2 0.9 0.0027 17.4 0.1 1.8 2 0 0 2 2 2 1 CUE domain VCX_VCY PF15231.6 EGF80114.1 - 0.48 11.1 6.2 0.72 10.5 4.8 2.0 2 0 0 2 2 2 0 Variable charge X/Y family CLASP_N PF12348.8 EGF80115.1 - 2.4e-22 79.6 3.8 2e-21 76.6 1.8 2.7 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 EGF80115.1 - 0.05 14.2 0.5 1.9 9.1 0.2 3.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EGF80115.1 - 0.12 12.0 0.8 0.94 9.1 0.1 2.7 2 1 0 2 2 2 0 NUC173 domain MMS19_N PF14500.6 EGF80115.1 - 0.25 10.9 8.2 3.5 7.1 0.1 4.0 3 1 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DFP PF04127.15 EGF80116.1 - 9.8e-20 71.2 0.0 1.2e-11 44.8 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein TRAM_LAG1_CLN8 PF03798.16 EGF80117.1 - 1.1e-30 106.8 30.3 1.9e-30 106.1 30.3 1.4 1 0 0 1 1 1 1 TLC domain DUF4083 PF13314.6 EGF80117.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) C2 PF00168.30 EGF80118.1 - 5.6e-83 273.9 0.0 1e-20 74.0 0.0 6.4 6 0 0 6 6 6 6 C2 domain SMP_LBD PF17047.5 EGF80118.1 - 1.1e-05 25.0 0.0 0.16 11.4 0.0 2.9 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain zf-C2H2_9 PF16293.5 EGF80118.1 - 0.078 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) YtxC PF08812.11 EGF80118.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 YtxC-like family LAG1-DNAbind PF09271.11 EGF80119.1 - 2.9e-28 99.4 3.3 3.3e-28 99.2 0.9 2.5 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 EGF80119.1 - 9.4e-22 77.9 2.3 2.9e-09 37.3 0.0 3.7 1 1 0 2 2 2 2 Beta-trefoil DNA-binding domain Peptidase_M36 PF02128.15 EGF80120.1 - 6.7e-125 417.1 1.6 7.4e-125 417.0 1.6 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF80120.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M50B PF13398.6 EGF80120.1 - 0.22 11.1 0.1 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like JHY PF15261.6 EGF80121.1 - 2.4e-08 34.7 0.3 2.4e-08 34.7 0.3 4.9 6 1 0 6 6 6 2 Jhy protein Ax_dynein_light PF10211.9 EGF80122.1 - 1e-91 306.0 11.4 1.2e-91 305.8 11.4 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Syntaxin-6_N PF09177.11 EGF80122.1 - 0.16 12.6 5.2 0.3 11.7 5.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.9 EGF80122.1 - 0.42 10.8 14.4 15 5.8 14.5 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4164 PF13747.6 EGF80122.1 - 0.69 10.2 9.2 2.1 8.7 5.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF724 PF05266.14 EGF80122.1 - 0.86 9.4 10.8 1.3 8.8 9.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TSNAXIP1_N PF15739.5 EGF80122.1 - 1.5 9.2 12.7 1.4 9.3 3.4 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus APG6_N PF17675.1 EGF80122.1 - 1.9 9.0 16.9 0.94 10.0 14.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 EGF80122.1 - 5.9 7.2 7.2 6.8 7.0 5.7 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NUDIX PF00293.28 EGF80123.1 - 4.7e-05 23.4 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Nro1 PF12753.7 EGF80125.1 - 1.9e-14 53.5 9.8 8.7e-14 51.3 3.4 2.1 2 0 0 2 2 2 2 Nuclear pore complex subunit Nro1 MIT PF04212.18 EGF80125.1 - 0.00014 21.9 3.5 0.04 14.0 1.9 2.7 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EGF80125.1 - 0.016 15.4 0.6 0.078 13.2 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 COQ9 PF08511.11 EGF80125.1 - 0.063 13.1 0.3 0.53 10.1 0.1 2.5 2 0 0 2 2 2 0 COQ9 Proteasome PF00227.26 EGF80126.1 - 3.1e-45 154.0 0.0 3.5e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RNA_pol_Rpb2_6 PF00562.28 EGF80127.1 - 1.2e-106 357.1 0.0 3.1e-106 355.8 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGF80127.1 - 5.9e-31 107.6 0.0 1.1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGF80127.1 - 1.9e-28 98.4 0.0 3.8e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EGF80127.1 - 4.6e-23 81.0 0.0 9.7e-23 79.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EGF80127.1 - 1.2e-21 76.9 0.0 2.6e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGF80127.1 - 1.2e-19 70.7 0.0 2.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Pirin PF02678.16 EGF80128.1 - 2.6e-31 107.8 0.1 5.3e-31 106.8 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGF80128.1 - 3.5e-30 104.4 0.0 1.1e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGF80128.1 - 0.059 13.1 0.5 0.36 10.6 1.2 1.9 2 0 0 2 2 2 0 Cupin domain eIF3g PF12353.8 EGF80129.1 - 9.1e-42 142.4 0.8 1.6e-41 141.6 0.8 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGF80129.1 - 1.5e-16 60.0 0.0 2.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF80129.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif HTH_Tnp_Tc5 PF03221.16 EGF80130.1 - 5.4e-08 32.7 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.6 EGF80130.1 - 0.01 16.4 0.1 0.022 15.4 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EGF80130.1 - 0.12 12.5 0.1 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1580 PF07618.11 EGF80130.1 - 0.17 11.5 0.1 0.5 10.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1580) Methyltransf_16 PF10294.9 EGF80131.1 - 4.5e-13 49.3 0.1 5.9e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGF80131.1 - 3.4e-05 23.7 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF80131.1 - 0.0038 17.9 0.0 0.0068 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF80131.1 - 0.012 16.3 0.0 0.03 15.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGF80131.1 - 0.02 15.5 0.0 0.046 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF5098 PF17023.5 EGF80132.1 - 0.00011 21.4 1.1 0.0015 17.6 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5098) PH PF00169.29 EGF80132.1 - 0.024 15.2 0.1 0.25 11.9 0.0 2.5 1 1 0 2 2 2 0 PH domain Miga PF10265.9 EGF80132.1 - 0.49 9.3 9.0 0.028 13.4 0.8 2.2 2 0 0 2 2 2 0 Mitoguardin RRM_1 PF00076.22 EGF80133.1 - 0.0015 18.3 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF668 PF05003.12 EGF80133.1 - 0.035 14.6 0.0 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF668) SDH_alpha PF03313.15 EGF80134.1 - 3.1e-101 338.4 5.5 4.6e-101 337.9 5.5 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EGF80134.1 - 6.2e-59 198.8 0.1 1.4e-58 197.7 0.1 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 EGF80134.1 - 0.067 11.7 3.4 0.1 11.1 3.4 1.2 1 0 0 1 1 1 0 MmgE/PrpD family Peptidase_M26_C PF07580.14 EGF80136.1 - 0.11 10.9 0.1 0.12 10.9 0.1 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region CTD_bind PF04818.13 EGF80137.1 - 0.00047 20.9 0.0 0.0023 18.7 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SelP_N PF04592.14 EGF80138.1 - 1.5 8.2 6.7 1.8 7.9 6.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M16_C PF05193.21 EGF80139.1 - 3e-35 121.9 0.0 6.5e-35 120.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGF80139.1 - 3.2e-35 121.3 1.9 5.3e-35 120.6 0.3 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PCI PF01399.27 EGF80140.1 - 1.7e-14 54.2 0.2 1e-13 51.7 0.1 2.3 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 EGF80140.1 - 1.9e-08 34.3 0.0 6.1e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 CSN4/RPN5/eIF3a helix turn helix domain RPN7 PF10602.9 EGF80140.1 - 2.6e-05 24.0 0.4 4.3e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Peptidase_M36 PF02128.15 EGF80141.1 - 6.1e-104 348.1 0.0 6.9e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) CDC73_C PF05179.14 EGF80142.1 - 1.9e-47 160.9 1.3 2.4e-47 160.5 0.0 1.8 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EGF80142.1 - 7.7e-10 38.6 1.7 1.9e-07 30.7 0.0 2.0 1 1 1 2 2 2 2 Paf1 complex subunit CDC73 N-terminal Zds_C PF08632.10 EGF80143.1 - 1e-10 41.2 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Rep_fac-A_C PF08646.10 EGF80144.1 - 3.3e-47 159.9 5.1 3.9e-46 156.4 3.2 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EGF80144.1 - 2.5e-32 110.7 2.0 1.3e-31 108.4 0.1 2.8 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 EGF80144.1 - 9.2e-25 86.6 0.1 2.1e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EGF80144.1 - 2.8e-11 43.2 0.5 2.2e-09 37.2 0.0 3.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Ribosomal_L6 PF00347.23 EGF80145.1 - 7.6e-29 100.2 2.4 5.1e-16 59.1 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 IL32 PF15225.6 EGF80145.1 - 0.056 13.8 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 Interleukin 32 Ribosomal_S3_C PF00189.20 EGF80146.1 - 0.068 13.7 0.6 0.11 13.0 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain SIP1 PF04938.12 EGF80147.1 - 4.8e-51 173.6 0.1 9.1e-51 172.7 0.1 1.5 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) ERG4_ERG24 PF01222.17 EGF80148.1 - 5.3e-94 315.4 26.3 6.5e-94 315.1 26.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Antiterm PF03589.13 EGF80149.1 - 0.044 14.1 2.1 0.47 10.8 0.1 3.3 2 1 1 3 3 3 0 Antitermination protein TraU PF06834.11 EGF80149.1 - 0.059 12.6 0.3 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 TraU protein Cytokin_check_N PF10407.9 EGF80149.1 - 0.28 11.2 6.4 0.18 11.8 0.3 3.5 4 0 0 4 4 4 0 Cdc14 phosphatase binding protein N-terminus HOOK PF05622.12 EGF80150.1 - 4.3 5.4 54.6 0.1 10.7 20.1 3.0 2 1 1 3 3 3 0 HOOK protein Ank_2 PF12796.7 EGF80151.1 - 1.5e-40 137.7 33.1 4.9e-08 33.4 0.9 6.7 3 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF80151.1 - 6.3e-38 128.7 17.1 9.9e-06 26.0 0.1 8.3 7 2 1 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF80151.1 - 5e-33 112.7 23.5 0.00094 19.4 0.1 12.9 4 2 9 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF80151.1 - 3e-16 57.9 20.7 1.3 9.8 0.0 13.7 10 2 5 15 15 15 3 Ankyrin repeat Ank PF00023.30 EGF80151.1 - 7.9e-05 22.9 13.6 46 4.7 0.0 10.4 4 2 2 6 6 6 0 Ankyrin repeat VbhA PF18495.1 EGF80151.1 - 0.0012 18.6 4.1 15 5.6 0.0 5.8 8 0 0 8 8 8 2 Antitoxin VbhA TGBp3 PF02495.17 EGF80151.1 - 0.65 9.7 6.6 1.4e+02 2.2 0.0 6.0 9 0 0 9 9 9 0 Triple gene block 3 Tubulin PF00091.25 EGF80152.1 - 5.3e-71 238.9 0.0 7.5e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF80152.1 - 1.1e-44 151.7 0.8 1.8e-44 150.9 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGF80152.1 - 0.00031 21.1 0.0 0.0013 19.0 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGF80152.1 - 0.0098 15.1 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin like 7tm_1 PF00001.21 EGF80153.1 - 5.4e-22 78.4 7.3 6.4e-22 78.1 7.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PIN_6 PF17146.4 EGF80153.1 - 0.14 12.7 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 PIN domain of ribonuclease DUF5480 PF17576.2 EGF80153.1 - 3.8 7.6 8.5 9.2 6.3 0.5 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5480) RAB3GAP2_N PF14655.6 EGF80155.1 - 1.1e-96 324.6 0.3 1.1e-96 324.6 0.3 1.6 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus RAB3GAP2_C PF14656.6 EGF80155.1 - 3.4e-18 65.2 1.3 3.4e-18 65.2 1.3 2.2 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit C-terminus RCC1 PF00415.18 EGF80156.1 - 1.2e-17 64.2 5.6 2e-08 34.7 0.0 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF80156.1 - 3.1e-16 58.7 6.5 2.3e-07 30.5 0.0 3.7 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat His_biosynth PF00977.21 EGF80157.1 - 6e-32 111.0 0.0 7.9e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGF80157.1 - 0.042 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family RRM_1 PF00076.22 EGF80158.1 - 8.7e-36 121.6 0.3 1.4e-12 47.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGF80158.1 - 9.5e-19 68.3 0.1 2.5e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 EGF80158.1 - 0.0014 18.6 0.2 4.1 7.5 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGF80158.1 - 0.021 14.9 0.2 0.45 10.7 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif TPR_1 PF00515.28 EGF80159.1 - 1.4e-20 72.2 5.0 0.00052 19.7 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGF80159.1 - 7.9e-19 66.3 1.6 0.017 15.2 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80159.1 - 1.7e-16 59.0 10.2 0.0028 17.7 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80159.1 - 1.5e-14 52.8 8.4 0.0035 17.3 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80159.1 - 1.8e-14 53.8 7.9 0.0034 17.7 0.1 5.3 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGF80159.1 - 2.4e-12 46.7 1.0 0.17 12.6 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF80159.1 - 1.8e-08 34.5 0.1 2.5 9.2 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF80159.1 - 1.3e-06 28.0 0.6 6.8e-05 22.4 0.1 2.2 1 1 1 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 EGF80159.1 - 1.9e-06 28.0 3.2 0.084 13.1 0.1 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGF80159.1 - 0.00014 21.8 1.3 0.0039 17.2 0.0 3.8 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 EGF80159.1 - 0.0002 21.4 0.0 0.4 10.9 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF80159.1 - 0.00021 21.7 0.2 0.49 10.9 0.2 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF80159.1 - 0.00027 21.5 0.4 4.9 7.9 0.1 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 EGF80159.1 - 0.00059 19.6 5.8 16 5.1 0.0 5.2 3 1 3 6 6 6 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 EGF80159.1 - 6.2 6.8 0.0 6.2 6.8 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Nuc_recep-AF1 PF11825.8 EGF80160.1 - 0.37 10.8 3.1 2 8.5 0.4 2.7 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 APH PF01636.23 EGF80161.1 - 2.2e-13 50.7 0.1 2.5e-08 34.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGF80161.1 - 2.1e-11 43.7 0.0 3.1e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EGF80161.1 - 7.1e-11 42.0 0.0 1.4e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF80161.1 - 1.2e-10 41.1 0.1 8.3e-10 38.4 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGF80161.1 - 5e-07 29.3 0.0 8.3e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGF80161.1 - 0.00018 21.2 0.0 0.00056 19.6 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EGF80161.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Rcd1 PF04078.13 EGF80161.1 - 0.056 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like RB_B PF01857.20 EGF80161.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain DUF1679 PF07914.11 EGF80161.1 - 0.07 12.0 0.1 0.49 9.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Ribosomal_L11 PF00298.19 EGF80162.1 - 7.2e-26 90.5 0.5 7.2e-26 90.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EGF80162.1 - 1.2e-24 85.9 1.2 5.3e-24 83.8 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain 7tm_2 PF00002.24 EGF80162.1 - 0.063 12.5 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) CDC37_N PF03234.14 EGF80164.1 - 4.4e-27 95.5 6.6 4.4e-27 95.5 6.6 3.3 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EGF80164.1 - 5.6e-20 71.4 3.8 1.7e-19 69.8 0.1 3.1 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EGF80164.1 - 2e-05 24.6 0.9 0.00029 20.9 0.0 2.9 2 0 0 2 2 2 1 Cdc37 C terminal domain Rhodanese PF00581.20 EGF80165.1 - 5.1e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Cyclin_N PF00134.23 EGF80166.1 - 4.2e-19 68.5 0.9 1.3e-18 67.0 0.9 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2536 PF10750.9 EGF80166.1 - 0.0086 15.9 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2536) ORC5_C PF14630.6 EGF80167.1 - 1.2e-61 208.7 0.2 1.5e-61 208.5 0.2 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus FAST_2 PF08368.12 EGF80167.1 - 0.026 15.3 0.1 15 6.4 0.0 2.7 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 PEPCK_ATP PF01293.20 EGF80168.1 - 5.9e-226 750.6 0.0 6.8e-226 750.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EGF80168.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 EGF80170.1 - 6.5e-43 145.1 0.2 4.9e-42 142.3 0.3 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGF80170.1 - 6.7e-22 77.3 0.0 1.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGF80170.1 - 5.6e-21 74.8 0.0 1.5e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF80170.1 - 1.8e-10 40.6 0.2 4.2e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EGF80170.1 - 0.00018 20.6 0.8 0.0028 16.7 0.4 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EGF80170.1 - 0.028 14.0 0.1 11 5.5 0.0 3.4 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF80170.1 - 0.53 10.2 2.2 15 5.4 1.6 3.1 2 1 0 2 2 2 0 RsgA GTPase SRP_TPR_like PF17004.5 EGF80171.1 - 3.2e-11 43.3 2.3 3.2e-11 43.3 2.3 3.8 3 1 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 EGF80171.1 - 4.5e-11 43.0 4.2 4.5e-11 43.0 4.2 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 EGF80171.1 - 2.3e-08 33.5 15.9 0.7 10.2 0.7 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGF80171.1 - 3.8e-06 27.3 12.5 0.37 11.3 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF80171.1 - 1.1e-05 25.8 6.9 0.29 12.1 0.4 6.6 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80171.1 - 5.8e-05 23.3 11.3 0.45 10.8 0.2 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80171.1 - 0.00089 19.3 10.0 1 9.7 0.1 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGF80171.1 - 0.0046 16.6 0.3 0.12 12.1 0.0 3.5 3 0 0 3 3 3 1 TPR repeat BTAD PF03704.17 EGF80171.1 - 0.016 15.7 0.8 1.7 9.1 0.0 4.0 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 EGF80171.1 - 0.032 14.4 0.4 1.5 9.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF80171.1 - 0.032 14.4 17.2 0.36 11.1 1.1 5.9 4 2 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 YfdX PF10938.8 EGF80171.1 - 0.33 10.9 4.3 5.5 6.9 0.1 3.9 2 1 1 4 4 4 0 YfdX protein TPR_16 PF13432.6 EGF80171.1 - 0.4 11.4 8.3 1.6 9.5 0.1 4.7 6 1 0 6 6 5 0 Tetratricopeptide repeat LPD25 PF18840.1 EGF80172.1 - 0.32 11.6 2.6 0.24 11.9 0.3 1.9 2 1 0 2 2 2 0 Large polyvalent protein associated domain 25 PNPase PF03726.14 EGF80172.1 - 1.4 9.4 5.1 1.4 9.4 1.1 2.2 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Glycolytic PF00274.19 EGF80173.1 - 2.2e-175 582.4 0.0 2.5e-175 582.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I FCH PF00611.23 EGF80174.1 - 3.4e-16 59.3 5.0 4.2e-16 59.0 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EGF80174.1 - 2.8e-12 46.0 0.1 7.9e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGF80174.1 - 1.9e-10 40.5 0.1 3.6e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF80174.1 - 1.6e-08 34.1 0.0 2.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain M157 PF11624.8 EGF80174.1 - 0.084 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 MHC class I-like protein M157 DUF4210 PF13915.6 EGF80175.1 - 4.9e-31 107.1 0.5 2.3e-30 105.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EGF80175.1 - 5.4e-22 77.7 1.9 7.3e-22 77.3 0.6 2.0 2 0 0 2 2 2 1 Chromosome segregation during meiosis ATG13 PF10033.9 EGF80175.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 13 WD40 PF00400.32 EGF80176.1 - 1.4e-33 114.3 14.1 1.8e-07 31.7 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80176.1 - 3.5e-10 40.0 0.1 0.2 12.0 0.0 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF80176.1 - 8.6e-05 22.5 0.1 0.13 12.1 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGF80176.1 - 0.00024 19.9 3.0 0.092 11.4 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.11 EGF80176.1 - 0.039 12.8 0.1 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) PQQ_2 PF13360.6 EGF80176.1 - 0.1 12.2 0.0 0.61 9.6 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain FKBP_C PF00254.28 EGF80177.1 - 1.2e-69 230.7 0.0 3.2e-35 120.3 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Stork_head PF10264.9 EGF80178.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Nop16 PF09420.10 EGF80179.1 - 4.2e-30 105.4 7.3 1.5e-29 103.5 7.3 1.9 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF3808 PF10300.9 EGF80180.1 - 6.3e-85 285.7 0.1 7.4e-85 285.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 EGF80180.1 - 0.0023 18.4 0.0 1.2 9.9 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80180.1 - 0.012 15.9 0.1 0.2 12.0 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80180.1 - 0.018 15.2 3.4 0.04 14.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF80180.1 - 0.024 14.5 0.3 0.088 12.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF80180.1 - 0.072 13.2 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Velvet PF11754.8 EGF80181.1 - 9.1e-46 156.8 0.7 9.1e-46 156.8 0.7 1.6 2 0 0 2 2 2 1 Velvet factor HNH_2 PF13391.6 EGF80182.1 - 1.5e-05 25.0 0.0 5.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGF80182.1 - 0.17 12.1 2.0 1.2 9.3 2.0 2.4 1 1 0 1 1 1 0 HNH endonuclease DUF4407 PF14362.6 EGF80183.1 - 0.21 10.9 15.0 0.3 10.4 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_UL6 PF01763.16 EGF80183.1 - 0.92 8.0 10.6 1.5 7.3 10.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like NAM-associated PF14303.6 EGF80183.1 - 5.1 7.8 37.0 0.34 11.6 22.0 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DUF5399 PF17377.2 EGF80184.1 - 0.2 11.5 1.7 0.31 10.9 1.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5399) Med19 PF10278.9 EGF80184.1 - 2 8.3 12.2 2.4 8.1 12.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NARP1 PF12569.8 EGF80184.1 - 3.6 6.4 8.0 3.6 6.4 8.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 EGF80184.1 - 7.9 6.5 9.4 10 6.2 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal U79_P34 PF03064.16 EGF80184.1 - 8.2 5.7 13.4 10 5.4 13.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GET2 PF08690.10 EGF80185.1 - 5.5e-07 29.6 4.7 6.5e-07 29.3 2.2 2.3 2 1 0 2 2 2 1 GET complex subunit GET2 L51_S25_CI-B8 PF05047.16 EGF80186.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HNH_2 PF13391.6 EGF80187.1 - 1.4e-05 25.2 0.2 0.00069 19.7 0.0 2.9 2 0 0 2 2 2 1 HNH endonuclease zf-UBP_var PF17807.1 EGF80187.1 - 0.089 12.6 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Variant UBP zinc finger HNH PF01844.23 EGF80187.1 - 0.097 12.9 1.8 1.2 9.4 1.8 2.5 1 1 0 1 1 1 0 HNH endonuclease Cytochrome_C7 PF14522.6 EGF80187.1 - 0.14 12.2 2.2 5.5 7.1 2.2 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF80187.1 - 1.3 8.8 4.9 19 5.1 1.9 2.9 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Ribosomal_S19 PF00203.21 EGF80189.1 - 1.5e-32 111.3 0.2 2e-32 110.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 EGF80189.1 - 0.008 16.2 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH Yip1 PF04893.17 EGF80190.1 - 1e-09 38.3 8.5 1.4e-09 37.9 8.5 1.2 1 0 0 1 1 1 1 Yip1 domain LRR_6 PF13516.6 EGF80190.1 - 0.047 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeat Peptidase_S8 PF00082.22 EGF80191.1 - 1.2e-40 139.7 0.4 1.6e-40 139.3 0.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EGF80191.1 - 1.8e-23 82.3 0.3 3.6e-23 81.4 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain RPN7 PF10602.9 EGF80192.1 - 1.6e-53 181.0 0.3 1.6e-53 181.0 0.3 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EGF80192.1 - 3.5e-14 53.2 0.3 1.3e-13 51.4 0.0 2.1 3 0 0 3 3 3 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EGF80192.1 - 0.02 14.9 0.2 0.079 12.9 0.1 2.0 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family HTH_17 PF12728.7 EGF80192.1 - 0.11 12.7 0.1 5.8 7.2 0.0 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EGF80192.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain IF-2B PF01008.17 EGF80193.1 - 2.3e-71 240.3 0.8 2.6e-71 240.1 0.8 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TPP_enzyme_N PF02776.18 EGF80193.1 - 0.084 12.5 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DAHP_synth_2 PF01474.16 EGF80194.1 - 9.4e-198 657.1 0.0 1.1e-197 656.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family TetR_C_31 PF17940.1 EGF80194.1 - 0.043 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LSM PF01423.22 EGF80195.1 - 1.9e-20 72.3 0.2 2.1e-20 72.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain Ribosomal_L26 PF16906.5 EGF80196.1 - 9.9e-40 134.9 4.7 1.2e-39 134.6 4.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGF80196.1 - 3.5e-07 29.9 2.5 3.5e-07 29.9 2.5 2.0 2 1 0 2 2 2 1 KOW motif DUF4663 PF15668.5 EGF80196.1 - 0.066 12.3 0.3 0.072 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Ank_2 PF12796.7 EGF80197.1 - 4e-15 56.2 0.0 9.6e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGF80197.1 - 2e-14 52.3 0.1 4.8e-06 26.5 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGF80197.1 - 1e-13 51.0 0.4 1.1e-05 25.6 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGF80197.1 - 5e-13 49.3 0.2 5.8e-12 45.9 0.2 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF80197.1 - 1e-12 48.0 0.6 7.8e-06 26.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF80198.1 - 1.9e-12 46.2 0.5 0.00018 21.7 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGF80198.1 - 3.9e-12 46.2 0.7 3.9e-06 27.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF80198.1 - 5.1e-11 43.0 0.1 6.3e-10 39.5 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF80198.1 - 1.1e-10 41.8 0.4 2.1e-08 34.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF80198.1 - 1.6e-10 40.9 1.6 0.00036 20.8 0.6 3.1 3 0 0 3 3 3 3 Ankyrin repeat AA_permease_2 PF13520.6 EGF80199.1 - 2.4e-59 201.3 45.1 3e-59 201.0 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF80199.1 - 2.3e-45 155.1 41.8 3e-45 154.7 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGF80199.1 - 1.5e-07 31.3 3.8 1.5e-07 31.3 3.8 3.9 7 0 0 7 7 7 1 C-terminus of AA_permease Cadherin_C_2 PF16492.5 EGF80199.1 - 0.63 10.8 4.8 2.8 8.7 0.0 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal AA_permease_2 PF13520.6 EGF80200.1 - 1.1e-57 195.9 30.6 2.5e-57 194.6 30.4 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 EGF80200.1 - 5e-36 124.3 40.7 1.1e-35 123.2 40.7 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGF80200.1 - 7.5e-08 32.3 2.3 7.5e-08 32.3 2.3 3.3 4 1 0 4 4 4 1 C-terminus of AA_permease MpPF26 PF07666.11 EGF80200.1 - 7.6 6.7 11.8 12 6.1 1.5 3.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 zf-CCCH PF00642.24 EGF80201.1 - 5.6e-19 67.6 37.9 0.00032 20.5 2.3 5.1 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGF80201.1 - 6.6e-19 67.3 43.8 3.3e-05 23.8 2.8 6.0 5 1 0 5 5 5 5 Zinc finger domain Torus PF16131.5 EGF80201.1 - 2.9e-14 53.7 29.6 0.00035 21.2 0.4 5.0 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EGF80201.1 - 3.5e-12 45.8 34.9 4.6e-05 23.1 0.2 5.6 5 1 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGF80201.1 - 1.3e-07 31.8 31.5 0.0011 19.4 0.7 5.4 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGF80201.1 - 1.1e-06 28.8 7.7 1.1e-06 28.8 7.7 2.6 1 1 1 2 2 2 1 Zinc-finger containing family ShK PF01549.24 EGF80201.1 - 0.16 12.5 0.3 0.16 12.5 0.3 4.3 1 1 3 4 4 4 0 ShK domain-like zf-C3H1 PF10650.9 EGF80201.1 - 0.27 11.0 24.5 0.76 9.6 0.1 5.2 5 1 0 5 5 5 0 Putative zinc-finger domain SNRNP27 PF08648.12 EGF80202.1 - 0.00031 20.7 0.4 0.0012 18.8 0.4 2.1 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_jaz PF12171.8 EGF80202.1 - 0.011 16.0 0.2 0.018 15.3 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Latexin PF06907.12 EGF80202.1 - 0.014 14.9 0.2 0.022 14.3 0.2 1.2 1 0 0 1 1 1 0 Latexin zf-C2H2_4 PF13894.6 EGF80202.1 - 0.028 15.2 0.1 0.061 14.2 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 EGF80202.1 - 0.034 14.5 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type CDC13_N PF16853.5 EGF80202.1 - 0.045 13.3 0.7 0.058 12.9 0.7 1.2 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus zf-C2H2 PF00096.26 EGF80202.1 - 0.087 13.3 0.4 0.16 12.5 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nkap_C PF06047.11 EGF80203.1 - 1.4e-45 153.6 1.4 1.4e-45 153.6 1.4 2.1 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain ABC_tran PF00005.27 EGF80204.1 - 3.9e-45 153.7 0.0 6e-28 98.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGF80204.1 - 3e-27 96.0 36.4 4.7e-15 56.0 17.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 EGF80204.1 - 7.1e-06 26.1 0.3 0.0086 16.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGF80204.1 - 0.00012 22.0 0.2 0.14 11.9 0.1 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGF80204.1 - 0.00065 19.2 3.1 0.95 8.9 0.1 3.8 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGF80204.1 - 0.0011 18.7 4.4 0.0021 17.8 0.1 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGF80204.1 - 0.007 16.8 0.1 0.032 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGF80204.1 - 0.012 15.6 0.7 0.52 10.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EGF80204.1 - 0.018 15.6 0.6 0.063 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGF80204.1 - 0.051 13.7 0.2 0.051 13.7 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 EGF80204.1 - 0.15 12.1 3.5 2.8 7.9 0.1 2.8 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 EGF80204.1 - 0.19 10.7 1.6 0.51 9.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NPL4 PF05021.15 EGF80205.1 - 1.7e-120 402.1 0.1 2.2e-120 401.6 0.1 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGF80205.1 - 8.2e-65 217.4 0.3 1.7e-64 216.3 0.3 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region Acyl-CoA_dh_1 PF00441.24 EGF80206.1 - 3e-46 157.3 1.7 4.3e-46 156.8 1.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGF80206.1 - 2.5e-25 89.3 0.1 6.1e-25 88.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGF80206.1 - 3.6e-24 84.8 0.2 2.2e-23 82.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGF80206.1 - 4.9e-23 81.9 0.1 4.9e-23 81.9 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 EGF80206.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 Staphylococcal AgrD protein HpaB_N PF11794.8 EGF80206.1 - 0.098 12.3 0.1 0.53 9.9 0.1 2.1 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal RPN6_N PF18055.1 EGF80208.1 - 1.5e-39 135.0 0.1 4.9e-39 133.3 0.1 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGF80208.1 - 6.3e-17 62.0 0.1 3.6e-16 59.6 0.1 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EGF80208.1 - 1.4e-14 53.5 0.4 3.5e-14 52.2 0.4 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EGF80208.1 - 0.014 15.7 3.7 4.5 7.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF80208.1 - 0.033 13.6 0.6 0.065 12.6 0.6 1.4 1 0 0 1 1 1 0 MalT-like TPR region DUF2935 PF11155.8 EGF80208.1 - 0.086 13.2 0.0 1.5 9.1 0.0 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF4246 PF14033.6 EGF80210.1 - 2.3e-33 116.0 1.6 1.1e-28 100.6 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) Arm PF00514.23 EGF80210.1 - 0.00025 21.0 0.0 0.0025 17.8 0.0 2.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EGF80210.1 - 0.026 14.0 0.2 0.098 12.1 0.0 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 EGF80210.1 - 0.15 12.2 0.4 2.2 8.4 0.0 2.9 2 2 0 2 2 2 0 V-ATPase subunit H DUF1221 PF06760.11 EGF80211.1 - 0.026 14.0 2.4 0.038 13.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) TRPM_tetra PF16519.5 EGF80211.1 - 0.46 10.6 3.2 0.3 11.2 0.9 1.8 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF3275 PF11679.8 EGF80211.1 - 0.5 10.3 3.1 0.39 10.7 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Mucin PF01456.17 EGF80211.1 - 6.1 6.8 16.3 1.3 9.0 2.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein AAA_16 PF13191.6 EGF80212.1 - 0.0081 16.6 0.1 0.038 14.4 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain Arm PF00514.23 EGF80213.1 - 0.0022 18.0 0.0 1.7 8.8 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF4246 PF14033.6 EGF80213.1 - 0.009 15.2 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF5578 PF17741.1 EGF80213.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5578) NADH_u_ox_C PF12853.7 EGF80213.1 - 0.12 12.3 0.2 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Pkinase PF00069.25 EGF80214.1 - 8.3e-30 104.0 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80214.1 - 3.6e-16 59.2 0.0 5.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 EGF80217.1 - 2.4e-27 95.3 0.1 1.1e-26 93.3 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGF80217.1 - 0.055 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGF80217.1 - 0.094 12.3 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase RL10P_insert PF17777.1 EGF80218.1 - 2.5e-25 88.3 0.0 3.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGF80218.1 - 2.8e-21 75.5 0.1 3.9e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Mg_trans_NIPA PF05653.14 EGF80219.1 - 1.2e-11 44.3 12.5 1.1e-05 24.7 4.2 2.4 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGF80219.1 - 9.4e-05 22.6 10.7 9.4e-05 22.6 10.7 3.0 3 0 0 3 3 3 1 EamA-like transporter family DUF3098 PF11297.8 EGF80219.1 - 0.034 13.7 0.5 0.53 9.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) M-inducer_phosp PF06617.13 EGF80219.1 - 0.057 12.7 1.3 0.07 12.4 0.1 1.6 2 0 0 2 2 2 0 M-phase inducer phosphatase tRNA_int_end_N2 PF12928.7 EGF80220.1 - 2e-10 40.7 0.0 4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGF80220.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain PPR PF01535.20 EGF80221.1 - 0.00044 20.3 0.3 17 5.9 0.0 5.4 5 0 0 5 5 5 1 PPR repeat TPR_14 PF13428.6 EGF80221.1 - 0.0012 19.4 0.1 1.6e+02 3.6 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_3 PF13812.6 EGF80221.1 - 0.014 15.5 0.2 4 7.6 0.0 3.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Allantoicase PF03561.15 EGF80222.1 - 2.6e-83 277.2 0.0 1.7e-41 141.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat LigB PF02900.18 EGF80223.1 - 3.3e-42 144.5 0.0 3.6e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Velvet PF11754.8 EGF80224.1 - 1.6e-39 136.4 8.7 4.5e-21 75.9 0.2 3.5 2 1 2 4 4 4 3 Velvet factor Synaptobrevin PF00957.21 EGF80225.1 - 9.2e-14 51.0 0.1 1.4e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGF80225.1 - 9.4e-14 51.2 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain HSR PF03172.13 EGF80225.1 - 0.085 13.0 0.1 17 5.6 0.0 3.0 3 0 0 3 3 3 0 HSR domain Cgr1 PF03879.14 EGF80226.1 - 6.1e-18 65.2 30.7 9.2e-18 64.6 30.7 1.3 1 0 0 1 1 1 1 Cgr1 family Tup_N PF08581.10 EGF80227.1 - 0.046 14.0 0.5 0.046 14.0 0.5 7.1 7 2 2 9 9 9 0 Tup N-terminal WD40_alt PF14077.6 EGF80227.1 - 0.13 12.1 0.6 0.63 9.9 0.2 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif PhoU PF01895.19 EGF80227.1 - 4.2 7.9 12.5 1.2 9.6 0.6 5.1 4 2 3 7 7 7 0 PhoU domain Adhesin_P1_N PF18652.1 EGF80227.1 - 8.4 6.5 11.7 29 4.8 1.1 4.5 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain TRAM_LAG1_CLN8 PF03798.16 EGF80228.1 - 6.8e-33 114.1 21.3 7.7e-33 113.9 21.3 1.0 1 0 0 1 1 1 1 TLC domain Cyclin_C_2 PF16899.5 EGF80229.1 - 8.2e-18 64.7 0.6 4.1e-16 59.3 0.1 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EGF80229.1 - 4.4e-08 32.9 0.0 1.3e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF80229.1 - 0.032 14.3 0.2 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 Cyclin, C-terminal domain LMWPc PF01451.21 EGF80230.1 - 2.2e-19 70.3 0.0 2.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF2779 PF11074.8 EGF80230.1 - 0.039 14.4 0.0 0.056 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Ureidogly_lyase PF04115.12 EGF80232.1 - 3.3e-38 131.3 0.4 9.5e-38 129.8 0.4 1.6 1 1 0 1 1 1 1 Ureidoglycolate lyase Mei5 PF10376.9 EGF80233.1 - 0.029 14.2 0.7 0.058 13.3 0.7 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein Ctr PF04145.15 EGF80234.1 - 1.1e-18 68.3 11.3 8.8e-17 62.1 11.3 2.4 1 1 0 1 1 1 1 Ctr copper transporter family zf-C2H2 PF00096.26 EGF80235.1 - 1.2e-06 28.6 10.7 0.0051 17.2 1.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF80235.1 - 0.0013 19.1 3.1 0.0013 19.1 3.1 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF80235.1 - 0.0033 18.1 11.3 0.69 10.9 1.8 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGF80235.1 - 0.0045 17.3 3.8 0.018 15.3 3.5 2.3 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EGF80235.1 - 0.077 13.1 0.9 0.15 12.2 0.9 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger zf-CGNR PF11706.8 EGF80235.1 - 0.12 12.3 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 CGNR zinc finger DUF3275 PF11679.8 EGF80235.1 - 3.8 7.5 5.5 3.7 7.5 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Aminotran_1_2 PF00155.21 EGF80236.1 - 8e-32 110.8 0.1 1.3e-31 110.1 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DnaJ_CXXCXGXG PF00684.19 EGF80237.1 - 0.032 14.6 0.3 0.066 13.6 0.3 1.4 1 0 0 1 1 1 0 DnaJ central domain Anti-TRAP PF15777.5 EGF80237.1 - 0.65 10.0 2.0 2.3 8.3 2.0 1.9 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein ASH PF15780.5 EGF80238.1 - 1.7e-07 31.3 0.2 6.7e-05 23.0 0.1 2.8 2 1 1 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGF80238.1 - 0.0051 16.6 0.1 3.2 7.6 0.1 2.8 2 0 0 2 2 2 2 MSP (Major sperm protein) domain APC_u9 PF16633.5 EGF80238.1 - 0.092 13.9 0.7 0.22 12.7 0.7 1.6 1 0 0 1 1 1 0 Unstructured region on APC between 1st two creatine-rich regions TMEM131_like PF12371.8 EGF80238.1 - 0.11 12.8 0.9 1.2 9.4 0.5 2.7 2 0 0 2 2 2 0 Transmembrane protein 131-like Metallophos PF00149.28 EGF80239.1 - 1.1e-13 52.2 0.0 1.4e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ald_Xan_dh_C2 PF02738.18 EGF80240.1 - 3.2e-183 610.1 0.0 4.3e-183 609.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EGF80240.1 - 5.1e-44 150.0 0.0 1.4e-43 148.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 EGF80240.1 - 3.7e-30 103.8 0.1 8.8e-30 102.6 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 EGF80240.1 - 1.4e-29 102.7 0.1 2.8e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 EGF80240.1 - 2.3e-28 98.4 0.0 9.4e-28 96.4 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 EGF80240.1 - 1.3e-06 28.2 0.7 1.3e-06 28.2 0.7 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain tRNA_m1G_MT PF01746.21 EGF80241.1 - 1.7e-23 83.4 0.1 5.2e-23 81.8 0.0 1.9 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase L51_S25_CI-B8 PF05047.16 EGF80242.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-CDGSH PF09360.10 EGF80243.1 - 1.9e-15 56.8 0.6 4.9e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Cyclin_N PF00134.23 EGF80244.1 - 2.2e-43 147.0 1.6 5e-39 132.9 0.7 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF80244.1 - 3.5e-22 78.7 0.0 8.3e-22 77.5 0.0 1.7 1 1 0 1 1 1 1 Cyclin, C-terminal domain SART-1 PF03343.13 EGF80245.1 - 0.014 14.0 2.9 0.019 13.6 2.9 1.2 1 0 0 1 1 1 0 SART-1 family ABA_GPCR PF12430.8 EGF80246.1 - 6.9e-35 120.4 10.4 6.9e-35 120.4 10.4 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EGF80246.1 - 2.5e-22 78.7 0.1 9.4e-22 76.9 0.1 2.1 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal PIH1 PF08190.12 EGF80247.1 - 4.4e-31 107.6 0.2 7.8e-31 106.8 0.2 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGF80247.1 - 3.4e-14 53.0 0.0 8.9e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain PDT PF00800.18 EGF80248.1 - 2.8e-56 190.2 0.2 4e-56 189.7 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EGF80248.1 - 5.8e-07 29.2 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EGF80248.1 - 0.037 14.6 0.0 0.083 13.5 0.0 1.6 1 0 0 1 1 1 0 ACT domain XOO_2897-deam PF14440.6 EGF80248.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase LETM1 PF07766.13 EGF80249.1 - 1.1e-23 84.0 0.3 1.3e-23 83.8 0.3 1.1 1 0 0 1 1 1 1 LETM1-like protein SH3_9 PF14604.6 EGF80250.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF80250.1 - 1e-05 25.1 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain WD40 PF00400.32 EGF80251.1 - 3.6e-34 116.2 6.7 2.1e-07 31.5 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80251.1 - 3.3e-20 72.2 0.0 0.0011 19.2 0.0 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF80251.1 - 5.6e-09 35.4 0.2 0.0021 17.1 0.0 3.3 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGF80251.1 - 6.2e-06 25.0 0.0 0.045 12.3 0.1 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain eIF2A PF08662.11 EGF80251.1 - 0.00017 21.6 0.0 1.1 9.1 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A CSTF1_dimer PF16699.5 EGF80251.1 - 0.00082 19.1 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain VID27 PF08553.10 EGF80251.1 - 0.00098 18.3 0.0 0.047 12.7 0.0 2.3 2 1 0 2 2 2 1 VID27 C-terminal WD40-like domain DUF4686 PF15742.5 EGF80252.1 - 1.5 7.9 72.8 0.74 8.9 43.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) zf-rbx1 PF12678.7 EGF80253.1 - 7.8e-10 38.9 5.8 1.3e-09 38.2 5.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGF80253.1 - 4.6e-09 36.5 7.0 8.9e-09 35.5 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF80253.1 - 5.6e-08 32.5 6.2 8.1e-08 32.0 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF80253.1 - 1.1e-07 31.6 5.3 1.9e-07 30.9 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF80253.1 - 2e-07 30.8 5.7 3.6e-07 29.9 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF80253.1 - 2.6e-06 27.4 1.4 3.8e-06 26.8 0.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGF80253.1 - 5.8e-05 23.1 0.5 0.00011 22.2 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGF80253.1 - 0.00016 21.4 5.5 0.0022 17.8 5.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF80253.1 - 0.00024 20.9 3.6 0.00062 19.6 3.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGF80253.1 - 0.0041 16.7 0.9 0.0041 16.7 0.9 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGF80253.1 - 0.0082 15.9 5.4 0.0082 15.9 5.4 2.9 2 1 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 EGF80253.1 - 0.072 13.3 3.6 0.2 11.8 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EGF80253.1 - 0.56 10.4 5.2 1.5 9.0 5.3 1.7 1 1 0 1 1 1 0 RING-variant domain DEAD PF00270.29 EGF80254.1 - 4.7e-19 68.8 0.1 1.1e-18 67.7 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF80254.1 - 6.8e-07 29.4 0.0 1.4e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF80254.1 - 0.038 14.3 0.2 0.39 11.1 0.0 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGF80254.1 - 0.057 13.7 0.1 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Aha1_N PF09229.11 EGF80255.1 - 3.9e-34 117.8 0.2 6.2e-34 117.1 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGF80255.1 - 2.4e-16 60.1 0.1 5e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Asp PF00026.23 EGF80256.1 - 6.2e-17 62.0 0.2 8.6e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80256.1 - 5.2e-07 29.6 0.0 1.6e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF80256.1 - 0.11 13.2 0.2 1.4 9.6 0.1 2.5 2 0 0 2 2 2 0 Aspartyl protease DUF2870 PF11069.8 EGF80257.1 - 0.0066 16.8 1.1 0.014 15.8 0.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2870) POP1 PF06978.11 EGF80257.1 - 0.081 12.9 0.7 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 PRKG1_interact PF15898.5 EGF80257.1 - 0.12 13.3 5.3 0.19 12.6 0.7 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Pneumo_att_G PF05539.11 EGF80257.1 - 0.2 11.2 8.3 0.27 10.8 8.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TT_ORF2 PF02957.15 EGF80257.1 - 4.8 8.1 7.5 1.1 10.2 3.8 1.9 2 1 0 2 2 2 0 TT viral ORF2 zf-RING_2 PF13639.6 EGF80258.1 - 7.5e-06 26.2 1.0 1.6e-05 25.1 1.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGF80258.1 - 6.1e-05 23.2 1.6 6.1e-05 23.2 1.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF80258.1 - 0.00023 20.9 0.7 0.00052 19.8 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF80258.1 - 0.0039 16.9 0.7 0.0079 15.9 0.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGF80258.1 - 0.0043 16.6 0.6 0.0096 15.5 0.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EGF80258.1 - 0.016 15.3 0.4 0.025 14.7 0.4 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_UBOX PF13445.6 EGF80258.1 - 0.017 15.1 2.2 0.03 14.3 0.5 2.3 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGF80258.1 - 0.049 13.6 0.5 0.15 12.0 0.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF80258.1 - 0.061 13.2 0.9 0.14 12.1 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EGF80258.1 - 0.069 13.2 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger zf-ANAPC11 PF12861.7 EGF80258.1 - 0.083 12.9 3.0 0.21 11.6 1.8 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EGF80258.1 - 0.096 12.9 0.8 0.28 11.4 0.8 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EGF80258.1 - 0.9 9.7 3.8 0.66 10.1 1.0 2.3 2 1 0 2 2 2 0 RING-variant domain Pkinase PF00069.25 EGF80259.1 - 2.5e-12 46.7 1.0 1.8e-11 43.9 1.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGF80259.1 - 2e-05 24.6 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGF80259.1 - 0.00013 21.7 0.1 0.00032 20.3 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EGF80259.1 - 0.00037 19.9 1.6 0.00039 19.8 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGF80259.1 - 0.00081 18.8 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF80259.1 - 0.0045 16.6 0.1 0.0089 15.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGF80259.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kinase-PolyVal PF18762.1 EGF80259.1 - 0.074 13.0 1.0 0.2 11.6 0.3 2.0 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Tom6 PF17112.5 EGF80260.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Ribosomal_L36e PF01158.18 EGF80262.1 - 0.071 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e Peptidase_M36 PF02128.15 EGF80263.1 - 1.1e-127 426.2 0.7 1.3e-127 426.1 0.7 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF80263.1 - 0.0033 17.3 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain PHF5 PF03660.14 EGF80264.1 - 2.3e-48 162.7 8.1 2.6e-48 162.5 8.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGF80264.1 - 0.004 15.1 0.6 0.0045 14.9 0.6 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 EGF80264.1 - 0.025 14.9 11.1 0.17 12.3 1.9 2.4 1 1 1 2 2 2 0 C1 domain DZR PF12773.7 EGF80264.1 - 0.11 12.6 9.2 1.3 9.1 8.0 2.6 1 1 1 2 2 2 0 Double zinc ribbon MitMem_reg PF13012.6 EGF80265.1 - 8.1e-27 93.9 1.6 1.4e-26 93.1 1.6 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGF80265.1 - 3.6e-16 59.2 0.1 6.6e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ODAM PF15424.6 EGF80265.1 - 0.032 13.8 0.7 0.049 13.2 0.7 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family WD40 PF00400.32 EGF80266.1 - 1.3e-43 146.1 26.6 3.9e-07 30.7 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGF80266.1 - 8.3e-12 44.8 0.4 2e-11 43.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGF80266.1 - 1.9e-11 44.1 6.4 0.34 11.2 0.1 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF80266.1 - 8.4e-09 35.2 5.9 0.00058 19.3 1.1 1.9 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EGF80266.1 - 1.3e-08 34.0 6.8 0.27 9.8 0.1 5.5 1 1 3 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.33 EGF80266.1 - 6.3e-08 32.3 1.4 8.7e-08 31.9 0.2 2.0 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.6 EGF80266.1 - 1.4e-06 28.1 0.1 3e-05 23.7 0.1 2.4 1 1 0 1 1 1 1 PQQ-like domain DUF5046 PF16465.5 EGF80266.1 - 0.001 18.6 0.2 1.2 8.5 0.0 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 EGF80266.1 - 0.0021 17.0 7.5 3.2 6.6 0.0 5.2 2 2 4 6 6 6 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 EGF80266.1 - 0.025 13.7 0.0 0.51 9.4 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Frtz PF11768.8 EGF80266.1 - 0.027 12.8 2.3 1.1 7.5 0.2 2.9 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_C3G PF12381.8 EGF80266.1 - 0.055 12.9 1.4 1.3 8.5 0.0 3.1 3 1 1 4 4 4 0 Tungro spherical virus-type peptidase BRK PF07533.16 EGF80266.1 - 0.058 13.0 0.0 20 4.9 0.0 3.7 4 0 0 4 4 4 0 BRK domain FBPase PF00316.20 EGF80267.1 - 9.4e-66 220.9 0.5 1.2e-65 220.5 0.5 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EGF80267.1 - 0.00048 19.7 0.0 0.002 17.7 0.0 2.0 3 0 0 3 3 3 1 Inositol monophosphatase family RHH_3 PF12651.7 EGF80267.1 - 0.19 11.7 0.1 0.45 10.5 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain CFAP91 PF14738.6 EGF80268.1 - 3.7e-58 195.9 11.5 3.7e-58 195.9 11.5 2.9 3 0 0 3 3 3 1 Cilia- and flagella-associated protein 91 Maelstrom PF13017.6 EGF80268.1 - 0.13 11.9 1.9 0.16 11.6 0.3 2.0 2 0 0 2 2 2 0 piRNA pathway germ-plasm component NICE-3 PF07406.11 EGF80269.1 - 7.4e-05 22.8 0.0 8.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 EGF80269.1 - 0.0059 16.8 0.0 0.0093 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Pkinase PF00069.25 EGF80270.1 - 1.4e-65 221.3 0.0 1.6e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80270.1 - 1.1e-33 116.6 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGF80270.1 - 5.2e-09 36.7 0.6 9.2e-09 35.9 0.6 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGF80270.1 - 1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Glyco_transf_52 PF07922.11 EGF80270.1 - 0.00053 19.4 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 52 Haspin_kinase PF12330.8 EGF80270.1 - 0.004 16.2 0.1 0.0056 15.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGF80270.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF80270.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF80270.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGF80270.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CLASP_N PF12348.8 EGF80271.1 - 2e-23 83.2 10.9 2.9e-09 36.8 0.2 6.4 5 3 1 6 6 6 4 CLASP N terminal Cnd1 PF12717.7 EGF80271.1 - 7.7e-13 48.8 11.0 0.00062 19.8 0.1 7.0 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF80271.1 - 7.7e-10 39.0 10.0 0.35 11.3 0.4 8.1 7 1 2 9 9 9 3 HEAT repeats HEAT PF02985.22 EGF80271.1 - 1.4e-08 34.2 21.9 0.18 12.1 0.0 10.6 12 0 0 12 12 12 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EGF80271.1 - 8.2e-06 26.3 0.2 1.1 9.9 0.0 6.3 4 2 3 7 7 7 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 EGF80271.1 - 0.00013 22.1 7.8 3.3 7.8 0.1 6.8 6 3 0 6 6 6 2 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 EGF80271.1 - 0.002 17.8 6.4 4.5 6.8 0.0 7.1 5 4 3 8 8 8 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EGF80271.1 - 0.0028 18.1 7.0 63 4.2 0.0 7.2 7 0 0 7 7 7 0 HEAT-like repeat DUF1241 PF06840.11 EGF80271.1 - 0.0044 16.7 2.0 0.05 13.3 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1241) RIX1 PF08167.12 EGF80271.1 - 0.06 13.1 6.2 1.2 8.8 0.0 4.7 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis AFP_2 PF18815.1 EGF80272.1 - 0.056 13.7 0.7 1.5 9.2 0.4 2.6 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat YEATS PF03366.16 EGF80273.1 - 4.3e-19 68.3 1.0 8.3e-19 67.3 0.0 2.1 3 0 0 3 3 3 1 YEATS family MitMem_reg PF13012.6 EGF80274.1 - 1.1e-26 93.5 1.1 1.8e-26 92.8 1.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGF80274.1 - 1.1e-13 51.2 0.1 1.9e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1126 PF06565.12 EGF80275.1 - 4.3e-99 325.4 4.0 5.2e-35 119.4 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain E1_dh PF00676.20 EGF80276.1 - 4.9e-114 380.3 0.3 5.9e-114 380.1 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGF80276.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EGF80276.1 - 0.00039 20.2 0.9 0.00086 19.1 0.9 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GAF_2 PF13185.6 EGF80277.1 - 7.3e-09 36.0 0.0 8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EGF80277.1 - 1.2e-06 29.2 0.0 1.2e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EGF80277.1 - 0.032 14.6 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 GAF domain Glyco_hydro_18 PF00704.28 EGF80278.1 - 4.4e-15 56.2 0.2 9.9e-15 55.0 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 EamA PF00892.20 EGF80279.1 - 7.9e-09 35.8 28.3 1.2e-05 25.4 4.2 3.4 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EGF80279.1 - 1.2e-06 28.1 6.2 0.00074 18.9 0.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EGF80279.1 - 1.5e-05 24.3 6.2 2.2e-05 23.8 6.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGF80279.1 - 2.3e-05 23.7 9.5 5.6e-05 22.5 9.5 1.7 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EGF80279.1 - 0.0016 17.5 2.9 0.061 12.3 0.1 3.1 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like Oxidored_q2 PF00420.24 EGF80279.1 - 0.038 13.6 2.5 0.15 11.7 1.2 2.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2975 PF11188.8 EGF80279.1 - 2.4 8.0 7.3 27 4.7 0.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Transketolase_N PF00456.21 EGF80280.1 - 5.4e-145 482.5 0.1 9.3e-145 481.7 0.1 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGF80280.1 - 7.9e-47 159.2 0.0 1.5e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGF80280.1 - 2.1e-11 43.8 0.0 6e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGF80280.1 - 4.1e-05 22.9 0.1 7.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MCD PF05292.11 EGF80281.1 - 7.3e-32 110.9 0.0 5.5e-25 88.4 0.0 2.4 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain Rhomboid PF01694.22 EGF80285.1 - 4.3e-06 26.8 7.1 5.9e-06 26.4 7.1 1.2 1 0 0 1 1 1 1 Rhomboid family UBA PF00627.31 EGF80285.1 - 8e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain DUF1751 PF08551.10 EGF80285.1 - 0.016 15.8 0.1 0.033 14.8 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) UBA_3 PF09288.10 EGF80285.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain TssN PF17555.2 EGF80285.1 - 0.71 9.2 4.7 0.39 10.0 1.2 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssN IQ PF00612.27 EGF80286.1 - 7.1e-06 25.4 39.3 0.012 15.3 1.1 6.4 7 0 0 7 7 7 5 IQ calmodulin-binding motif Elf1 PF05129.13 EGF80287.1 - 3.5e-28 97.4 3.9 3.9e-28 97.3 3.9 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 EGF80287.1 - 0.0037 16.6 1.0 0.005 16.2 1.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn-ribbon_8 PF09723.10 EGF80287.1 - 0.0065 16.6 2.9 0.018 15.2 2.9 1.7 1 1 1 2 2 2 2 Zinc ribbon domain TnsD PF15978.5 EGF80287.1 - 0.11 11.5 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D Nucleoporin_FG PF13634.6 EGF80288.1 - 3.2e-06 27.9 35.2 1.9e-05 25.4 11.3 4.1 2 2 1 3 3 3 2 Nucleoporin FG repeat region Dna2 PF08696.11 EGF80288.1 - 0.078 12.8 0.6 5.9 6.6 0.0 2.4 1 1 0 2 2 2 0 DNA replication factor Dna2 Fib_alpha PF08702.10 EGF80288.1 - 0.4 10.8 8.0 0.77 9.9 3.5 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 EGF80289.1 - 1.2e-56 187.4 33.4 3.8e-09 37.0 0.1 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80289.1 - 3.2e-16 59.4 2.3 0.019 15.3 0.1 5.8 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF80289.1 - 1.7e-10 40.2 7.0 0.0012 17.6 0.1 4.4 1 1 1 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EGF80289.1 - 1.3e-07 31.7 0.8 0.00024 21.1 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EGF80289.1 - 0.027 14.4 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 LisH Pox_A_type_inc PF04508.12 EGF80289.1 - 0.077 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Coatomer_WDAD PF04053.14 EGF80289.1 - 0.11 11.5 0.1 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region BROMI PF14961.6 EGF80290.1 - 1.6e-172 575.8 11.7 4.6e-114 382.2 7.0 3.1 2 1 0 2 2 2 2 Broad-minded protein RabGAP-TBC PF00566.18 EGF80290.1 - 1e-05 25.3 5.9 2.3e-05 24.2 5.9 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain JAB PF01398.21 EGF80291.1 - 2.4e-19 69.4 0.0 5.3e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EGF80291.1 - 1.3e-12 47.9 1.8 1.7e-12 47.5 0.2 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 EGF80291.1 - 4.9e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TraC_F_IV PF11130.8 EGF80291.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Peptidase_M41 PF01434.18 EGF80292.1 - 9.3e-64 214.8 1.0 1.6e-63 214.0 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGF80292.1 - 6.4e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF80292.1 - 2.5e-10 40.0 0.0 5.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGF80292.1 - 6.2e-07 30.0 1.8 4.2e-05 24.0 0.2 3.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGF80292.1 - 1.9e-06 27.7 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGF80292.1 - 4.5e-06 26.7 0.0 1.8e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGF80292.1 - 9.9e-06 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGF80292.1 - 1.9e-05 24.5 0.0 0.00037 20.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 EGF80292.1 - 0.00029 20.1 0.0 0.00086 18.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGF80292.1 - 0.0011 19.3 0.1 0.022 15.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF80292.1 - 0.0063 17.1 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF80292.1 - 0.007 16.1 0.1 0.021 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGF80292.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGF80292.1 - 0.011 16.0 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGF80292.1 - 0.018 14.9 0.1 3.5 7.5 0.0 3.1 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EGF80292.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGF80292.1 - 0.024 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGF80292.1 - 0.025 14.2 0.2 0.5 9.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGF80292.1 - 0.025 14.4 0.0 0.087 12.7 0.0 1.9 2 1 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 EGF80292.1 - 0.029 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 EGF80292.1 - 0.036 13.4 0.2 0.093 12.1 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGF80292.1 - 0.036 14.0 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 EGF80292.1 - 0.046 13.8 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EGF80292.1 - 0.053 13.0 0.0 0.46 10.0 0.0 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGF80292.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 EGF80292.1 - 0.1 11.9 0.2 0.27 10.5 0.2 1.7 1 1 0 1 1 1 0 Zeta toxin DnaJ PF00226.31 EGF80293.1 - 1.1e-10 41.4 0.1 3.1e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Rib_recp_KP_reg PF05104.12 EGF80293.1 - 10 7.2 12.1 1.9 9.5 6.4 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region GTP_cyclohydro2 PF00925.20 EGF80294.1 - 2.8e-62 209.1 0.0 3.8e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Metalloenzyme PF01676.18 EGF80295.1 - 2.2e-77 259.8 0.1 2.5e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 EGF80295.1 - 5.3e-73 245.0 0.0 7.1e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 EGF80295.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGF80295.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Peptidase_S41 PF03572.18 EGF80296.1 - 7.8e-14 51.6 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.24 EGF80296.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain TRAP-delta PF05404.12 EGF80296.1 - 0.079 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Asp PF00026.23 EGF80297.1 - 6.5e-14 52.1 0.0 4.8e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGF80297.1 - 0.0019 18.8 0.6 0.0064 17.1 0.6 2.0 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGF80297.1 - 0.017 15.7 0.1 0.062 13.9 0.1 2.1 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGF80297.1 - 0.083 12.7 0.0 0.68 9.7 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal EF-hand_1 PF00036.32 EGF80298.1 - 8.3e-16 56.3 1.1 4.4e-07 29.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGF80298.1 - 2.9e-13 48.6 4.3 6.4e-07 28.8 0.3 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGF80298.1 - 2.8e-12 45.5 2.7 6.5e-06 25.4 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGF80298.1 - 5.1e-10 39.7 4.1 1.1e-05 25.8 0.4 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGF80298.1 - 8.5e-07 28.7 2.4 0.0068 16.2 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 EGF80298.1 - 0.0012 18.8 1.3 0.028 14.3 0.0 2.7 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGF80298.1 - 0.0096 16.2 0.0 0.35 11.2 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 EGF80298.1 - 0.19 11.9 0.0 21 5.3 0.0 2.1 1 1 1 2 2 2 0 EF hand cNMP_binding PF00027.29 EGF80299.1 - 3.7e-07 30.1 0.0 0.00068 19.7 0.0 3.4 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGF80300.1 - 7e-25 87.9 0.0 9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80300.1 - 7.9e-14 51.6 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF80300.1 - 4.1e-10 39.0 0.0 5.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF80300.1 - 0.0011 19.0 0.0 0.0094 15.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF80300.1 - 0.01 15.2 1.3 0.3 10.4 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGF80300.1 - 0.022 13.8 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FA_desaturase PF00487.24 EGF80301.1 - 4.6e-15 56.2 20.5 7.1e-15 55.5 20.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGF80301.1 - 6.3e-14 51.9 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mg_trans_NIPA PF05653.14 EGF80303.1 - 3.6e-81 272.5 26.3 4.3e-81 272.2 26.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGF80303.1 - 6.7e-06 26.3 6.8 6.7e-06 26.3 6.8 3.9 2 2 1 3 3 3 2 EamA-like transporter family DUF2937 PF11157.8 EGF80303.1 - 0.23 11.1 1.6 2.8 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) rve_2 PF13333.6 EGF80304.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain LIDHydrolase PF10230.9 EGF80305.1 - 1.2e-57 195.5 0.4 1.5e-57 195.2 0.4 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGF80305.1 - 0.0002 20.7 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGF80305.1 - 0.038 13.8 0.2 0.49 10.1 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGF80305.1 - 0.13 12.0 1.1 0.25 11.0 1.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EGF80305.1 - 0.18 12.4 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3040 PF11239.8 EGF80306.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Rubrerythrin PF02915.17 EGF80308.1 - 0.015 15.7 2.8 0.023 15.1 2.8 1.3 1 0 0 1 1 1 0 Rubrerythrin Arm PF00514.23 EGF80309.1 - 0.0009 19.2 0.2 0.074 13.1 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat DUF4246 PF14033.6 EGF80309.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Pkinase PF00069.25 EGF80310.1 - 3.1e-29 102.1 0.0 4.4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80310.1 - 3.2e-15 56.1 0.0 5.5e-15 55.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.6 EGF80311.1 - 1.2e-05 25.3 0.1 0.00044 20.3 0.0 2.5 2 0 0 2 2 2 2 HNH endonuclease NOC3p PF07540.11 EGF80313.1 - 0.072 13.5 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Nucleolar complex-associated protein Sec2p PF06428.11 EGF80313.1 - 0.21 11.6 2.5 6.9 6.7 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF80313.1 - 0.6 10.3 4.7 14 5.9 4.6 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ndc1_Nup PF09531.10 EGF80314.1 - 3 6.4 10.9 3.4 6.2 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WDCP PF15390.6 EGF80314.1 - 3.5 5.9 9.7 18 3.5 9.7 1.8 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family VGLL4 PF15245.6 EGF80315.1 - 2.9 7.9 8.2 3.7 7.6 5.2 2.1 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 Serglycin PF04360.12 EGF80316.1 - 0.004 17.1 3.3 0.049 13.6 0.1 2.5 2 0 0 2 2 2 1 Serglycin GPS2_interact PF15784.5 EGF80316.1 - 0.12 12.8 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KRTAP PF11759.8 EGF80316.1 - 0.22 12.1 10.5 0.86 10.2 4.7 2.4 2 0 0 2 2 2 0 Keratin-associated matrix Keratin_2_head PF16208.5 EGF80316.1 - 0.75 9.9 9.0 3.9 7.6 2.9 2.4 2 0 0 2 2 2 0 Keratin type II head DASH_Dad2 PF08654.10 EGF80316.1 - 1 9.8 3.9 1.7 9.1 0.4 2.8 3 1 0 3 3 3 0 DASH complex subunit Dad2 WXG100 PF06013.12 EGF80316.1 - 1.1 9.5 4.1 13 6.1 0.4 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG CH_2 PF06294.11 EGF80317.1 - 3.4e-15 55.9 0.0 1.3e-14 54.1 0.0 2.1 1 0 0 1 1 1 1 CH-like domain in sperm protein ADK PF00406.22 EGF80317.1 - 1.2e-08 35.1 0.5 0.0003 20.9 0.0 4.1 3 1 0 3 3 3 1 Adenylate kinase Hydin_ADK PF17213.3 EGF80317.1 - 9.6e-05 22.7 0.0 9.6e-05 22.7 0.0 4.2 4 0 0 4 4 4 1 Hydin Adenylate kinase-like domain CH PF00307.31 EGF80317.1 - 0.00046 20.3 0.3 0.002 18.3 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain AAA_33 PF13671.6 EGF80317.1 - 0.017 15.2 1.6 0.11 12.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGF80317.1 - 0.09 13.3 0.0 0.09 13.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EGF80317.1 - 0.38 11.2 0.0 0.38 11.2 0.0 4.1 3 1 0 3 3 3 0 AAA domain FIVAR PF07554.13 EGF80317.1 - 0.73 10.6 10.5 2.5 8.9 0.6 4.3 3 0 0 3 3 3 0 FIVAR domain Pterin_bind PF00809.22 EGF80318.1 - 2.6e-77 259.8 0.2 4.2e-77 259.1 0.2 1.3 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 EGF80318.1 - 7.2e-51 171.4 1.5 6e-27 94.4 0.6 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 EGF80318.1 - 1.7e-36 125.1 0.0 5.3e-36 123.5 0.0 1.9 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF561 PF04481.12 EGF80318.1 - 0.15 11.2 2.2 16 4.6 0.0 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF561) CPSase_L_D2 PF02786.17 EGF80319.1 - 1.7e-114 380.6 0.5 4.2e-83 278.0 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 EGF80319.1 - 3.3e-45 154.2 0.0 6.5e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EGF80319.1 - 2e-44 150.5 0.0 5.6e-44 149.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 EGF80319.1 - 5.8e-44 149.7 0.0 1.5e-43 148.4 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EGF80319.1 - 4.4e-41 140.0 0.1 9.9e-41 138.9 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGF80319.1 - 8.6e-33 113.6 0.1 2.9e-32 111.9 0.1 2.0 2 0 0 2 2 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EGF80319.1 - 1.4e-17 63.6 0.0 1.2e-16 60.7 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EGF80319.1 - 1e-16 61.1 1.7 2.1e-09 37.2 0.3 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGF80319.1 - 1.5e-16 60.4 0.3 9e-09 35.1 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGF80319.1 - 6e-10 39.0 0.0 4.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EGF80319.1 - 1.1e-05 25.3 0.8 0.0003 20.6 0.2 2.6 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 EGF80319.1 - 2.3e-05 24.5 0.9 0.16 12.0 0.2 2.9 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EGF80319.1 - 0.021 14.6 0.4 0.14 11.9 0.1 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DDE_Tnp_1_4 PF13701.6 EGF80319.1 - 0.056 11.7 0.0 0.094 11.0 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain group 1 TrkA_N PF02254.18 EGF80319.1 - 0.083 13.2 0.0 0.56 10.5 0.0 2.5 3 0 0 3 3 2 0 TrkA-N domain PPTA PF01239.22 EGF80320.1 - 8.7e-37 123.8 9.5 1.7e-09 37.1 0.2 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TSNAXIP1_N PF15739.5 EGF80321.1 - 7.8e-25 87.4 4.5 7.8e-25 87.4 4.5 3.6 2 1 2 4 4 4 1 Translin-associated factor X-interacting N-terminus DUF4248 PF14053.6 EGF80321.1 - 0.2 11.7 0.5 38 4.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF948 PF06103.11 EGF80321.1 - 5.3 7.4 11.5 1.3 9.4 0.6 3.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DNA_pol_B PF00136.21 EGF80322.1 - 1.2e-139 466.0 0.1 2.2e-139 465.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGF80322.1 - 3.2e-79 266.5 0.0 4.9e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGF80322.1 - 2.3e-16 60.0 6.8 4.8e-16 59.0 6.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_A_exo1 PF01612.20 EGF80322.1 - 0.012 15.3 0.1 0.027 14.2 0.1 1.6 1 0 0 1 1 1 0 3'-5' exonuclease DNA_pol_B_exo2 PF10108.9 EGF80322.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 EGF80322.1 - 0.03 13.2 0.0 0.063 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EGF80322.1 - 0.088 12.8 0.0 0.4 10.7 0.0 2.1 1 1 0 1 1 1 0 RNase_H superfamily DUF1476 PF07345.11 EGF80322.1 - 0.16 12.4 0.5 8.5 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta Prok-RING_1 PF14446.6 EGF80322.1 - 0.33 10.9 8.0 0.1 12.5 1.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 EGF80322.1 - 4.2 7.5 6.8 8.9 6.4 6.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon BACK PF07707.15 EGF80323.1 - 0.051 13.7 0.3 0.12 12.5 0.3 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch MMR_HSR1 PF01926.23 EGF80324.1 - 2e-16 60.1 0.2 2.4e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF80324.1 - 4.8e-11 42.4 0.8 2.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF80324.1 - 1.6e-06 28.1 0.0 3.1e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EGF80324.1 - 3.3e-05 23.3 0.2 0.00014 21.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family IIGP PF05049.13 EGF80324.1 - 0.0002 20.6 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 EGF80324.1 - 0.0055 16.8 1.7 1.6 8.8 0.1 2.7 2 1 1 3 3 3 2 Dynamin family AAA_18 PF13238.6 EGF80324.1 - 0.018 15.6 0.5 0.064 13.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGF80324.1 - 0.063 13.5 0.2 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Csm2_III-A PF03750.13 EGF80324.1 - 0.12 13.2 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Csm2 Type III-A MeaB PF03308.16 EGF80324.1 - 0.31 10.0 0.9 1.1 8.2 0.1 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UBN_AB PF14075.6 EGF80325.1 - 4e-16 59.4 2.3 5.2e-15 55.8 2.3 2.5 1 1 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 EGF80325.1 - 3e-12 46.4 0.8 5.7e-12 45.4 0.8 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain BppL_N PF18338.1 EGF80325.1 - 0.069 12.9 1.5 0.99 9.3 0.2 2.7 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain SbsC_C PF18058.1 EGF80327.1 - 0.0024 18.1 4.3 0.0024 18.1 4.3 1.8 2 0 0 2 2 2 1 SbsC C-terminal domain MF_alpha_N PF05436.11 EGF80327.1 - 0.026 14.4 0.4 0.055 13.4 0.4 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus PEPcase_2 PF14010.6 EGF80327.1 - 0.038 12.5 1.5 0.05 12.1 1.5 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase HalX PF08663.10 EGF80327.1 - 0.043 14.1 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 HalX domain WAK_assoc PF14380.6 EGF80327.1 - 0.057 14.1 0.6 0.057 14.1 0.6 2.6 3 0 0 3 3 3 0 Wall-associated receptor kinase C-terminal TMPIT PF07851.13 EGF80327.1 - 3.4 6.8 22.6 0.055 12.7 13.3 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF2730 PF10805.8 EGF80327.1 - 3.5 7.8 7.8 15 5.8 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Flagellin_N PF00669.20 EGF80327.1 - 5.1 7.2 9.6 0.3 11.2 1.8 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4246 PF14033.6 EGF80328.1 - 3.1e-84 283.7 1.6 4e-84 283.3 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RepB-RCR_reg PF10723.9 EGF80330.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Replication regulatory protein RepB Fib_alpha PF08702.10 EGF80330.1 - 0.058 13.6 0.7 0.08 13.1 0.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WASH_WAHD PF11945.8 EGF80330.1 - 0.064 12.8 1.3 0.61 9.6 0.7 2.0 1 1 1 2 2 2 0 WAHD domain of WASH complex Exonuc_VII_L PF02601.15 EGF80330.1 - 0.12 11.9 0.8 0.16 11.6 0.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EGF80330.1 - 0.22 11.6 1.6 0.94 9.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MutS_IV PF05190.18 EGF80330.1 - 2.1 8.7 6.5 1.1 9.7 3.5 1.9 2 0 0 2 2 2 0 MutS family domain IV DUF4246 PF14033.6 EGF80331.1 - 1.8e-81 274.6 1.2 2.3e-81 274.2 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Receptor_2B4 PF11465.8 EGF80331.1 - 0.16 12.2 0.0 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Lyase_1 PF00206.20 EGF80333.1 - 1e-22 80.9 0.1 1.5e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGF80333.1 - 3.9e-14 52.9 0.1 1.8e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Aminotran_5 PF00266.19 EGF80334.1 - 1.2e-15 57.3 0.0 2.9e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGF80334.1 - 1.4e-07 31.1 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGF80334.1 - 0.035 12.6 0.0 0.066 11.7 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MMR_HSR1 PF01926.23 EGF80335.1 - 5.5e-17 61.9 0.1 5.2e-15 55.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF80335.1 - 2.8e-07 30.2 0.1 2.2e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF80335.1 - 2.9e-06 27.3 0.3 0.0073 16.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 EGF80335.1 - 0.0022 17.6 0.1 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EGF80335.1 - 0.033 14.3 3.7 0.04 14.0 0.2 2.7 3 1 1 4 4 4 0 Dynamin family AIG1 PF04548.16 EGF80335.1 - 0.035 13.4 0.2 0.079 12.3 0.0 1.7 2 0 0 2 2 2 0 AIG1 family FtsJ PF01728.19 EGF80336.1 - 9.2e-50 169.2 0.0 1.1e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EGF80336.1 - 0.15 11.9 0.0 0.45 10.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF1539 PF07560.11 EGF80337.1 - 0.0021 18.1 1.4 0.083 13.0 0.6 2.9 1 1 1 2 2 2 1 Domain of Unknown Function (DUF1539) PGDH_C PF16896.5 EGF80337.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term TMPIT PF07851.13 EGF80338.1 - 0.00094 18.5 5.4 0.00094 18.5 5.4 1.4 2 0 0 2 2 2 1 TMPIT-like protein EzrA PF06160.12 EGF80338.1 - 0.029 12.5 9.1 0.041 12.0 9.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FapA PF03961.13 EGF80338.1 - 0.062 11.9 2.5 0.088 11.4 2.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A WAK_assoc PF14380.6 EGF80338.1 - 0.54 11.0 4.1 0.59 10.9 0.2 2.7 2 1 1 3 3 3 0 Wall-associated receptor kinase C-terminal OmpH PF03938.14 EGF80338.1 - 6.5 7.1 12.8 2.2 8.6 9.5 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4246 PF14033.6 EGF80339.1 - 1.4e-93 314.5 0.0 1.9e-93 314.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) BpuSI_N PF15516.6 EGF80339.1 - 0.036 14.0 0.2 0.72 9.7 0.0 2.5 2 0 0 2 2 2 0 BpuSI N-terminal domain DUF1765 PF08578.10 EGF80339.1 - 0.28 11.7 2.0 0.33 11.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) Guanylate_cyc PF00211.20 EGF80341.1 - 2.9e-40 137.8 0.2 5.1e-40 137.1 0.2 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FHA PF00498.26 EGF80341.1 - 8.9e-18 64.4 0.1 2e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGF80341.1 - 2.2e-11 43.9 0.0 1.2e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain GAF_3 PF13492.6 EGF80341.1 - 5.1e-11 43.0 0.0 9.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EGF80341.1 - 9.8e-09 35.6 0.0 1.8e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EGF80341.1 - 6e-08 33.4 0.0 1.2e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain RRM_1 PF00076.22 EGF80342.1 - 0.00043 20.0 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxalase PF00903.25 EGF80343.1 - 0.00047 20.3 0.0 0.018 15.2 0.1 2.9 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Dimer_Tnp_hAT PF05699.14 EGF80345.1 - 2.8e-17 62.3 0.0 3e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 EGF80346.1 - 7.4e-10 39.1 0.5 1.2e-09 38.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF5344 PF17279.2 EGF80349.1 - 0.012 16.1 2.1 0.04 14.5 0.3 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Zein-binding PF04576.15 EGF80349.1 - 0.019 15.3 1.4 0.019 15.3 1.4 1.7 1 1 0 1 1 1 0 Zein-binding Wzy_C_2 PF11846.8 EGF80350.1 - 0.24 11.3 0.1 0.24 11.3 0.1 1.5 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Adeno_E3_CR2 PF02439.15 EGF80350.1 - 7.6 6.4 7.3 0.35 10.7 0.4 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 T5orf172 PF10544.9 EGF80352.1 - 0.25 11.9 1.0 2.1 8.9 0.1 2.4 1 1 1 2 2 2 0 T5orf172 domain MMR_HSR1 PF01926.23 EGF80353.1 - 8.3e-15 54.9 0.0 2.8e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF80353.1 - 1.3e-05 24.8 0.1 3.2e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF80353.1 - 0.00013 22.0 1.2 0.00031 20.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EGF80353.1 - 0.00018 21.5 0.0 0.002 18.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EGF80353.1 - 0.019 14.3 0.0 0.054 12.8 0.0 1.8 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 EGF80353.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 EGF80354.1 - 1.2e-58 198.5 0.0 2.9e-44 151.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80354.1 - 3.2e-25 88.9 0.0 4.5e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF80354.1 - 6.3e-07 29.0 0.0 1.9e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF80354.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF80354.1 - 0.00041 19.4 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGF80354.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGF80354.1 - 0.0027 16.5 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF80354.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CENP-P PF13096.6 EGF80354.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P P5CR_dimer PF14748.6 EGF80356.1 - 2.3e-37 127.4 0.2 5e-37 126.3 0.2 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGF80356.1 - 2.6e-15 56.8 0.7 8.5e-15 55.1 0.7 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGF80356.1 - 0.003 17.2 0.1 0.0058 16.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA zf-C3HC4_2 PF13923.6 EGF80357.1 - 1.1e-08 34.8 17.8 2.4e-08 33.7 11.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF80357.1 - 6.5e-08 32.5 7.8 6.5e-08 32.5 7.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF80357.1 - 4.6e-07 29.6 5.8 4.6e-07 29.6 5.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF80357.1 - 8e-07 28.8 10.8 8e-07 28.8 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF80357.1 - 5.2e-06 26.3 9.6 2.8e-05 24.0 7.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.27 EGF80357.1 - 5.3e-05 22.9 0.3 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 SAP domain zf-RING_2 PF13639.6 EGF80357.1 - 0.00013 22.2 8.9 0.00013 22.2 8.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGF80357.1 - 0.0021 18.2 11.5 0.0021 18.2 11.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGF80357.1 - 0.0023 17.7 14.1 0.075 12.9 9.8 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGF80357.1 - 0.0053 16.9 4.4 0.0053 16.9 4.4 1.9 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-WRNIP1_ubi PF18279.1 EGF80357.1 - 0.006 17.1 6.7 1.1 10.1 0.7 4.0 3 0 0 3 3 3 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_6 PF14835.6 EGF80357.1 - 0.022 14.6 2.8 0.022 14.6 2.8 1.8 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-Di19 PF05605.12 EGF80357.1 - 0.16 12.3 10.5 0.58 10.5 0.8 3.8 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 EGF80357.1 - 0.35 10.3 4.3 7.7 6.1 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EGF80357.1 - 0.37 10.8 9.4 0.46 10.5 3.3 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-C2HC_2 PF13913.6 EGF80357.1 - 1.3 9.0 4.9 69 3.5 0.0 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_4 PF14570.6 EGF80357.1 - 2 8.3 8.6 9.8 6.1 2.0 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain TRAF6_Z2 PF18048.1 EGF80357.1 - 3.7 7.7 7.8 2.1 8.5 0.4 3.2 4 0 0 4 4 3 0 TNF receptor-associated factor 6 zinc finger 2 Zn-ribbon_8 PF09723.10 EGF80357.1 - 6.5 7.0 6.6 3.6e+02 1.4 5.8 3.3 2 1 1 3 3 3 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 EGF80357.1 - 7.2 7.2 9.2 4.3 7.9 0.1 3.0 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain Peptidase_M17 PF00883.21 EGF80358.1 - 2.8e-120 401.3 0.0 3.6e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EGF80358.1 - 1.7e-12 47.3 0.8 3.6e-12 46.2 0.8 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PDZ_2 PF13180.6 EGF80358.1 - 0.093 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Phi_1 PF04674.12 EGF80359.1 - 4.9e-40 137.6 1.3 1.2e-39 136.3 1.3 1.6 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region SWI-SNF_Ssr4 PF08549.10 EGF80359.1 - 2.9 6.4 6.5 3.8 6.0 6.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ATPase_2 PF01637.18 EGF80360.1 - 1.1e-07 32.0 0.1 1.9e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGF80360.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGF80360.1 - 0.044 13.8 0.4 0.42 10.7 0.4 2.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF80360.1 - 0.046 14.1 0.0 0.3 11.5 0.0 2.5 1 1 0 1 1 1 0 RNA helicase AFG1_ATPase PF03969.16 EGF80360.1 - 0.097 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Laminin_I PF06008.14 EGF80361.1 - 0.06 13.0 0.4 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Laminin Domain I NMT1 PF09084.11 EGF80362.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Kinesin PF00225.23 EGF80363.1 - 0.013 14.5 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain AAA_22 PF13401.6 EGF80363.1 - 0.051 13.8 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF80363.1 - 0.06 12.8 0.2 1.4 8.4 0.0 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region Microtub_bd PF16796.5 EGF80363.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Microtubule binding Adeno_IVa2 PF02456.15 EGF80363.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.18 EGF80363.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EGF80363.1 - 0.16 12.3 0.1 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EGF80363.1 - 0.2 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 EGF80363.1 - 0.21 11.0 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein TBCC PF07986.12 EGF80364.1 - 3.5e-26 91.3 2.4 6.4e-26 90.5 2.4 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGF80364.1 - 1.3e-13 51.4 1.5 2.8e-13 50.3 1.5 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain GOLD_2 PF13897.6 EGF80365.1 - 6.2e-06 26.8 0.0 0.08 13.4 0.0 3.0 2 0 0 2 2 2 2 Golgi-dynamics membrane-trafficking MMM1 PF10296.9 EGF80365.1 - 2.1e-05 23.8 0.2 6.8e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PAC4 PF16093.5 EGF80365.1 - 0.17 12.1 2.1 20 5.4 0.0 3.0 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 AhpC-TSA PF00578.21 EGF80366.1 - 2.3e-36 124.5 0.0 2.9e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGF80366.1 - 2.7e-16 59.6 0.0 3.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGF80366.1 - 1.7e-10 40.6 0.0 2.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGF80366.1 - 0.051 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Sec2p PF06428.11 EGF80367.1 - 8e-20 70.6 16.0 8e-20 70.6 16.0 2.9 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p Macoilin PF09726.9 EGF80367.1 - 0.1 11.2 15.4 0.017 13.7 8.4 2.2 2 0 0 2 2 2 0 Macoilin family AAA PF00004.29 EGF80368.1 - 3.6e-44 150.4 0.0 4.7e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF80368.1 - 6.3e-11 41.9 0.4 1.1e-10 41.1 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGF80368.1 - 7.3e-06 26.0 0.1 2.2e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF80368.1 - 7.8e-06 26.4 0.1 4.6e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EGF80368.1 - 1.5e-05 25.2 0.0 3.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 EGF80368.1 - 4.4e-05 24.0 0.0 6.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 EGF80368.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGF80368.1 - 0.00034 20.6 0.0 0.013 15.4 0.0 2.1 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 EGF80368.1 - 0.00045 20.2 0.0 0.00068 19.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 EGF80368.1 - 0.00095 19.1 0.1 0.01 15.7 0.0 2.1 1 1 1 2 2 2 1 NACHT domain RuvB_N PF05496.12 EGF80368.1 - 0.00098 18.9 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGF80368.1 - 0.003 17.9 0.0 0.0057 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EGF80368.1 - 0.0045 17.3 0.1 0.023 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGF80368.1 - 0.0059 15.8 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EGF80368.1 - 0.0076 16.1 0.0 0.025 14.4 0.0 1.7 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_33 PF13671.6 EGF80368.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGF80368.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 EGF80368.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGF80368.1 - 0.027 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGF80368.1 - 0.034 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGF80368.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGF80368.1 - 0.049 13.3 0.0 0.16 11.7 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 EGF80368.1 - 0.051 12.8 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 EGF80368.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AFG1_ATPase PF03969.16 EGF80368.1 - 0.092 11.6 0.1 0.14 11.0 0.1 1.5 1 1 0 1 1 1 0 AFG1-like ATPase RsgA_GTPase PF03193.16 EGF80368.1 - 0.099 12.5 0.1 0.32 10.9 0.0 1.8 2 1 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EGF80368.1 - 0.14 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF80368.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGF80368.1 - 0.16 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 EGF80368.1 - 0.17 11.2 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATP-synt_ab PF00006.25 EGF80368.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 EGF80368.1 - 0.18 12.3 0.1 0.57 10.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain ATP-synt_G PF04718.15 EGF80369.1 - 2.4e-15 57.1 0.3 3.7e-15 56.6 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit TPR_1 PF00515.28 EGF80371.1 - 8.1e-18 63.4 9.8 3e-05 23.6 0.3 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80371.1 - 7.4e-16 56.9 17.0 0.00089 19.2 0.3 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80371.1 - 1.1e-12 47.0 8.2 0.0056 16.8 0.1 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF80371.1 - 8.1e-06 26.2 0.3 18 6.4 0.0 6.9 7 1 1 8 8 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGF80371.1 - 6.4e-05 22.3 0.3 0.015 14.6 0.0 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80371.1 - 6.8e-05 23.1 15.9 0.42 10.9 0.1 6.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF80371.1 - 0.0001 22.4 4.9 0.44 11.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF80371.1 - 0.0009 19.3 0.0 2.1 8.6 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF80371.1 - 0.00092 19.7 0.1 9.8 6.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF80371.1 - 0.0014 18.5 2.4 57 4.1 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF80371.1 - 0.0058 16.8 6.1 0.033 14.4 0.0 3.6 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EGF80371.1 - 0.012 15.8 4.5 0.031 14.5 0.1 3.6 3 1 1 4 4 3 0 PPR repeat TPR_16 PF13432.6 EGF80371.1 - 0.065 13.9 0.1 19 6.0 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGF80371.1 - 0.36 10.8 9.8 0.97 9.4 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGF80371.1 - 0.37 10.5 0.0 0.37 10.5 0.0 4.4 6 0 0 6 6 5 0 TPR repeat RPN7 PF10602.9 EGF80371.1 - 0.44 10.2 4.3 27 4.4 0.1 4.3 4 1 1 5 5 5 0 26S proteasome subunit RPN7 PPR_2 PF13041.6 EGF80371.1 - 1.1 9.5 3.1 2.4 8.4 0.2 2.7 2 0 0 2 2 2 0 PPR repeat family HlyIII PF03006.20 EGF80372.1 - 3.4e-37 128.3 26.4 4.3e-37 128.0 26.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related PLDc_N PF13396.6 EGF80372.1 - 0.68 9.9 0.1 0.68 9.9 0.1 3.1 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal EXOSC1 PF10447.9 EGF80373.1 - 7.5e-18 65.1 1.0 1.6e-13 51.2 0.3 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGF80373.1 - 1.5e-09 37.5 0.0 3.7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 EGF80373.1 - 0.014 15.7 0.1 0.18 12.2 0.1 2.5 2 1 0 2 2 2 0 S1 RNA binding domain TFIID-18kDa PF02269.16 EGF80374.1 - 4.6e-18 65.0 0.0 5.3e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Ribosomal_L44 PF00935.19 EGF80376.1 - 1.7e-35 121.3 11.3 2.5e-35 120.8 11.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Polysacc_deac_1 PF01522.21 EGF80377.1 - 1.2e-14 54.2 0.0 3.2e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase Ribosomal_L30_N PF08079.12 EGF80378.1 - 2.3e-28 98.3 9.0 2.3e-28 98.3 9.0 1.7 2 1 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGF80378.1 - 9.3e-19 67.1 1.5 1.8e-18 66.1 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e CSRNP_N PF16019.5 EGF80378.1 - 0.051 13.5 0.4 0.11 12.4 0.2 1.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus WD40 PF00400.32 EGF80379.1 - 1.5e-23 82.6 22.6 4.4e-07 30.5 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80379.1 - 5.6e-19 68.2 7.1 3e-07 30.6 0.1 4.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF80379.1 - 1.1e-07 31.9 0.7 0.088 12.7 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGF80379.1 - 2.3e-05 23.5 0.5 0.0088 15.0 0.1 3.4 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EGF80379.1 - 0.087 12.6 0.8 4.1 7.1 0.0 2.8 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF1921 PF09081.10 EGF80379.1 - 0.11 12.7 0.9 0.49 10.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) WD40_like PF17005.5 EGF80379.1 - 0.15 11.3 0.0 6.5 6.0 0.0 2.3 1 1 0 2 2 2 0 WD40-like domain TFIIIC_delta PF12657.7 EGF80379.1 - 0.36 10.7 4.1 1.6 8.6 4.1 2.3 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 EGF80379.1 - 0.43 8.5 1.7 0.71 7.8 0.6 1.8 1 1 1 2 2 2 0 IKI3 family WD40 PF00400.32 EGF80380.1 - 9.4e-22 76.9 17.6 7.2e-05 23.5 1.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80380.1 - 5.9e-10 39.3 0.4 0.00096 19.4 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SBD PF17882.1 EGF80380.1 - 0.0014 18.5 0.1 2.2 8.1 0.0 2.9 3 1 0 3 3 3 2 OAA-family lectin sugar binding domain LisH PF08513.11 EGF80380.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 LisH WD40_like PF17005.5 EGF80380.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain DUF4646 PF15496.6 EGF80381.1 - 0.26 11.9 0.1 0.26 11.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4646) Profilin PF00235.19 EGF80382.1 - 4.1e-19 69.1 0.0 5.1e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Profilin Glyco_transf_22 PF03901.17 EGF80383.1 - 2e-80 271.1 34.0 2.4e-80 270.8 34.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EGF80383.1 - 0.00012 22.3 14.9 0.00012 22.3 14.9 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase BTG PF07742.12 EGF80384.1 - 7e-26 90.4 0.0 1.4e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 BTG family TFIIA PF03153.13 EGF80384.1 - 9.1 6.2 11.0 13 5.7 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PALP PF00291.25 EGF80385.1 - 7.4e-85 284.9 0.1 1.1e-84 284.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGF80385.1 - 6.8e-33 112.3 0.0 1.5e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ion_trans_N PF08412.10 EGF80385.1 - 0.069 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Ion transport protein N-terminal Glyco_tran_WecB PF03808.13 EGF80385.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF1325 PF07039.11 EGF80386.1 - 3.6e-09 36.8 0.6 1.2e-08 35.2 0.6 1.9 1 0 0 1 1 1 1 SGF29 tudor-like domain COMPASS-Shg1 PF05205.12 EGF80386.1 - 5.6e-07 30.2 3.2 9.4e-07 29.5 0.1 3.0 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Tudor_3 PF18115.1 EGF80386.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain SVS_QK PF10578.9 EGF80387.1 - 0.81 10.4 7.0 3.1 8.6 2.8 4.8 2 0 0 2 2 2 0 Seminal vesicle protein repeat Sas10_Utp3 PF04000.15 EGF80388.1 - 6e-21 74.9 0.2 2.5e-20 72.9 0.4 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2321 PF10083.9 EGF80389.1 - 0.029 14.0 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DHBP_synthase PF00926.19 EGF80390.1 - 7.5e-82 273.5 0.0 9.1e-82 273.2 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TPT PF03151.16 EGF80391.1 - 0.00029 20.3 22.0 0.00041 19.8 22.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family RhoGAP PF00620.27 EGF80392.1 - 1.3e-45 155.0 0.0 7e-45 152.6 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EGF80392.1 - 4.1e-08 33.4 0.6 1.5e-07 31.6 0.2 2.3 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MRP-S23 PF10484.9 EGF80392.1 - 0.15 12.4 1.7 0.51 10.6 1.7 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 FAM184 PF15665.5 EGF80392.1 - 2.2 8.0 16.1 1 9.1 6.3 2.7 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF4293 PF14126.6 EGF80393.1 - 4.2 7.6 6.5 1.9 8.7 1.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Phosphodiest PF01663.22 EGF80394.1 - 2e-13 50.7 4.7 8.1e-13 48.7 0.6 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGF80394.1 - 5.3e-07 29.3 1.0 1.7e-06 27.7 0.2 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 EGF80394.1 - 0.0019 17.6 0.9 0.0039 16.6 0.9 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EGF80394.1 - 0.18 11.9 0.7 4.5 7.3 0.1 2.4 2 0 0 2 2 2 0 PglZ domain Alk_phosphatase PF00245.20 EGF80394.1 - 0.2 10.6 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase DUF229 PF02995.17 EGF80394.1 - 0.21 10.1 0.3 1.4 7.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Utp11 PF03998.13 EGF80395.1 - 1.9e-73 247.4 19.0 2.1e-73 247.3 19.0 1.0 1 0 0 1 1 1 1 Utp11 protein Ntox8 PF15545.6 EGF80395.1 - 0.26 11.4 2.2 0.4 10.8 0.2 2.2 2 0 0 2 2 2 0 Bacterial toxin 8 HAD_SAK_1 PF10307.9 EGF80396.1 - 1.1e-39 136.4 0.1 1.7e-39 135.8 0.1 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Wound_ind PF08186.11 EGF80396.1 - 0.075 13.5 0.3 0.32 11.4 0.0 2.1 2 0 0 2 2 2 0 Wound-inducible basic protein family Microtub_bind PF13931.6 EGF80396.1 - 0.47 10.8 2.9 1.1 9.6 2.9 1.6 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding IQ PF00612.27 EGF80397.1 - 3e-10 39.0 18.3 0.0004 19.9 0.9 4.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif DUF382 PF04037.13 EGF80398.1 - 3.7e-57 192.0 1.9 3.7e-57 192.0 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EGF80398.1 - 1.6e-18 66.3 6.9 2.9e-18 65.5 6.9 1.5 1 0 0 1 1 1 1 PSP SAP PF02037.27 EGF80398.1 - 3.2e-05 23.5 0.2 0.0065 16.2 0.0 2.7 2 0 0 2 2 2 2 SAP domain Mito_carr PF00153.27 EGF80399.1 - 3.5e-66 219.2 6.4 2.7e-21 75.3 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF80399.1 - 0.049 12.8 2.5 1.3 8.1 2.5 2.5 1 1 0 1 1 1 0 Gammaproteobacterial serine protease MRP-L20 PF12824.7 EGF80400.1 - 0.066 13.4 1.2 0.096 12.8 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 zf-RVT PF13966.6 EGF80401.1 - 1.5e-05 25.7 5.4 3.6e-05 24.4 1.0 3.0 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase UPF0193 PF05250.11 EGF80402.1 - 7.6e-34 117.4 1.6 1.1e-33 116.9 1.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) RPAP2_Rtr1 PF04181.13 EGF80403.1 - 9e-22 77.2 1.7 1.9e-21 76.2 1.7 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF2040 PF09745.9 EGF80403.1 - 0.088 12.9 0.3 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) GLTP PF08718.11 EGF80404.1 - 4.4e-46 156.8 0.0 5.9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pkinase PF00069.25 EGF80405.1 - 4.3e-72 242.6 0.0 5.2e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80405.1 - 7.2e-33 114.0 0.0 9e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGF80405.1 - 2.1e-10 41.1 2.7 4.1e-10 40.2 2.7 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGF80405.1 - 1.1e-06 28.2 0.1 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGF80405.1 - 1.5e-05 24.2 0.2 1.9e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGF80405.1 - 0.0034 17.0 0.1 0.29 10.7 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGF80405.1 - 0.0075 15.6 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pep_deformylase PF01327.21 EGF80406.1 - 5.3e-34 117.1 0.0 6.1e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase PMT PF02366.18 EGF80407.1 - 1.2e-76 257.5 15.4 2.8e-76 256.3 15.4 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGF80407.1 - 1.9e-60 203.9 15.5 5.2e-60 202.5 15.5 1.8 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGF80407.1 - 4.5e-27 95.1 0.0 7.6e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 MIR domain RPAP1_C PF08620.10 EGF80408.1 - 3.7e-21 75.0 0.0 8.2e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGF80408.1 - 3.4e-12 45.9 0.8 1.3e-11 44.1 0.8 2.0 1 0 0 1 1 1 1 RPAP1-like, N-terminal DUF89 PF01937.19 EGF80409.1 - 1.6e-82 277.3 0.6 2e-82 277.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Arm PF00514.23 EGF80410.1 - 1.8e-92 300.9 14.1 3.9e-13 48.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 EGF80410.1 - 1.6e-23 82.0 1.6 1.4e-22 79.0 1.8 2.2 2 0 0 2 2 2 1 Atypical Arm repeat IBB PF01749.20 EGF80410.1 - 1.7e-23 82.8 3.3 3.2e-22 78.8 5.1 2.2 3 0 0 3 3 2 1 Importin beta binding domain HEAT_2 PF13646.6 EGF80410.1 - 1.1e-19 70.6 0.0 3e-07 30.8 0.0 5.7 3 2 2 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 EGF80410.1 - 5.5e-19 68.3 1.9 2.8e-06 27.7 0.0 6.5 5 3 2 7 7 6 4 HEAT-like repeat HEAT PF02985.22 EGF80410.1 - 1.3e-16 59.3 3.8 0.0011 19.1 0.0 7.4 7 1 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 EGF80410.1 - 3.2e-09 36.6 0.3 0.018 14.5 0.0 4.1 1 1 4 5 5 5 2 Armadillo-like V-ATPase_H_C PF11698.8 EGF80410.1 - 1.6e-08 34.7 0.0 0.029 14.5 0.0 4.4 3 2 1 4 4 4 2 V-ATPase subunit H Adaptin_N PF01602.20 EGF80410.1 - 6.7e-08 31.5 0.0 7.8e-06 24.7 0.0 2.7 1 1 1 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.6 EGF80410.1 - 0.003 17.8 2.6 6.3 7.1 0.0 4.7 5 1 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 EGF80410.1 - 0.0052 16.8 0.5 10 6.2 0.0 4.5 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EGF80410.1 - 0.058 14.1 0.2 7.6 7.5 0.1 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Mo25 PF08569.11 EGF80410.1 - 0.076 12.4 0.1 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 Mo25-like DUF4468 PF14730.6 EGF80410.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold CRM1_repeat_3 PF18787.1 EGF80410.1 - 0.13 12.4 0.3 13 6.0 0.1 3.5 3 0 0 3 3 3 0 CRM1 / Exportin repeat 3 ParcG PF10274.9 EGF80410.1 - 0.15 12.2 0.0 33 4.5 0.0 2.9 2 1 0 2 2 2 0 Parkin co-regulated protein Pkinase PF00069.25 EGF80411.1 - 3.1e-71 239.8 0.0 3.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80411.1 - 5.5e-45 153.7 0.0 8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGF80411.1 - 1.7e-20 73.1 0.1 4.2e-20 71.8 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGF80411.1 - 3.4e-07 29.4 0.0 5.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF80411.1 - 3.9e-07 29.7 0.0 1.8e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGF80411.1 - 0.0088 16.0 0.1 3 7.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGF80411.1 - 0.053 12.9 0.1 0.25 10.7 0.0 1.7 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpb4 PF03874.16 EGF80414.1 - 6.1e-27 94.4 4.3 7.1e-27 94.2 4.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 YPEB PF14620.6 EGF80414.1 - 0.023 14.0 0.2 0.025 13.9 0.2 1.1 1 0 0 1 1 1 0 YpeB sporulation SNAD4 PF18750.1 EGF80414.1 - 0.09 12.9 0.2 0.27 11.4 0.2 1.7 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF4911 PF16256.5 EGF80414.1 - 0.15 12.1 0.2 2.4 8.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4911) HEAT PF02985.22 EGF80415.1 - 3e-07 30.1 4.7 13 6.3 0.0 10.6 12 0 0 12 12 12 1 HEAT repeat HEAT_2 PF13646.6 EGF80415.1 - 7.9e-07 29.4 0.0 33 5.0 0.0 7.5 8 1 0 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF80415.1 - 0.0019 18.7 4.5 2.8 8.6 0.0 5.7 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region WD40 PF00400.32 EGF80416.1 - 1.2e-14 54.5 10.0 0.0011 19.7 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80416.1 - 1.3e-05 25.4 0.0 0.013 15.8 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_J PF04911.12 EGF80419.1 - 2.8e-06 26.8 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase j chain DNA_pol_A_exo1 PF01612.20 EGF80420.1 - 8.7e-15 54.9 0.5 2e-14 53.7 0.5 1.6 1 0 0 1 1 1 1 3'-5' exonuclease Peptidase_S41 PF03572.18 EGF80421.1 - 2.5e-10 40.2 0.0 6.8e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.24 EGF80421.1 - 0.073 13.4 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 PDZ domain Maf1 PF09174.10 EGF80422.1 - 5.6e-52 176.4 0.0 7.5e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator tRNA-synt_2 PF00152.20 EGF80423.1 - 1e-76 258.0 0.0 1.4e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGF80423.1 - 4.8e-11 42.5 0.0 8.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGF80423.1 - 4.3e-08 33.0 0.0 0.00065 19.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 EGF80423.1 - 0.006 16.8 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Pkinase PF00069.25 EGF80424.1 - 1.7e-53 181.7 0.0 2e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80424.1 - 3.4e-32 111.7 0.0 4.2e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF80424.1 - 6.5e-05 21.9 0.0 9.9e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF80424.1 - 0.001 18.5 0.3 0.0014 18.0 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF80424.1 - 0.0022 17.6 0.2 0.0029 17.2 0.2 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGF80424.1 - 0.017 14.8 0.1 0.37 10.4 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGF80424.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF80424.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGF80424.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFIIA PF03153.13 EGF80425.1 - 3.8 7.4 34.4 6.3 6.7 34.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cmc1 PF08583.10 EGF80426.1 - 0.017 15.1 2.4 0.028 14.4 2.4 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NMT1_3 PF16868.5 EGF80426.1 - 0.12 11.8 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 NMT1-like family MPC PF03650.13 EGF80427.1 - 5.7e-30 103.7 0.2 6.2e-30 103.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Kelch_1 PF01344.25 EGF80428.1 - 2.1e-30 104.1 11.1 1.9e-05 24.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGF80428.1 - 3.2e-29 100.4 8.2 1e-07 31.7 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGF80428.1 - 6.2e-25 87.0 13.4 1.6e-06 28.0 0.5 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF80428.1 - 4.4e-24 83.9 10.6 4.9e-05 23.5 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 EGF80428.1 - 2e-21 75.1 11.4 1.4e-05 24.8 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGF80428.1 - 3.4e-17 62.3 22.9 0.00063 20.0 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain FA_desaturase PF00487.24 EGF80429.1 - 1.9e-25 90.1 6.8 3.6e-25 89.3 6.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGF80429.1 - 9.7e-11 41.0 0.7 1.9e-10 40.1 0.7 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) CENP-S PF15630.6 EGF80430.1 - 1.8e-18 66.6 0.1 2.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGF80430.1 - 6.6e-08 32.6 0.1 8.7e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 EGF80430.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 EGF80431.1 - 1e-61 206.3 0.0 1.1e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cys_Met_Meta_PP PF01053.20 EGF80432.1 - 2.6e-135 450.9 0.0 3e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGF80432.1 - 1.8e-07 30.7 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGF80432.1 - 1.9e-06 27.5 0.1 3.8e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGF80432.1 - 2.4e-05 23.4 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EGF80432.1 - 0.00023 19.8 0.0 0.00046 18.8 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase Methyltransf_29 PF03141.16 EGF80432.1 - 0.019 13.5 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Beta_elim_lyase PF01212.21 EGF80432.1 - 0.053 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase GDC-P PF02347.16 EGF80432.1 - 0.074 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein OTU PF02338.19 EGF80433.1 - 3.3e-10 40.6 0.1 7.1e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGF80433.1 - 5.3e-05 22.8 0.2 0.13 11.7 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain TRAPPC-Trs85 PF12739.7 EGF80433.1 - 0.38 9.7 2.1 0.5 9.3 0.1 1.9 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit NTP_transf_2 PF01909.23 EGF80434.1 - 1.5e-08 34.9 0.2 1.9e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGF80434.1 - 2.9e-06 27.4 0.3 2.9e-06 27.4 0.3 2.2 2 1 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGF80434.1 - 0.00012 22.1 0.1 0.00012 22.1 0.1 2.6 3 0 0 3 3 3 1 Polymerase beta, Nucleotidyltransferase DUF4667 PF15700.5 EGF80434.1 - 0.0038 17.4 5.0 0.0075 16.4 5.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) DUF4269 PF14091.6 EGF80434.1 - 0.071 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) NinG PF05766.12 EGF80434.1 - 0.08 12.9 7.7 0.16 11.9 7.7 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF1176 PF06674.11 EGF80434.1 - 7.6 5.9 11.9 12 5.2 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) 3-HAO PF06052.12 EGF80435.1 - 1.3e-57 193.7 0.1 1.5e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DZR PF12773.7 EGF80435.1 - 0.0012 18.8 2.3 0.0019 18.2 2.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon Cupin_2 PF07883.11 EGF80435.1 - 0.0021 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Nudix_N_2 PF14803.6 EGF80435.1 - 0.025 14.5 3.2 0.59 10.1 0.2 2.7 3 0 0 3 3 3 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 EGF80435.1 - 0.051 13.7 0.9 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-ACC PF17848.1 EGF80435.1 - 0.27 11.3 4.8 1.1 9.4 0.8 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SDA1 PF05285.12 EGF80436.1 - 0.0092 15.4 25.5 0.012 15.1 25.5 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EGF80436.1 - 0.096 12.0 26.6 0.15 11.4 26.6 1.3 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 EGF80436.1 - 0.4 9.2 31.6 0.56 8.7 31.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AJAP1_PANP_C PF15298.6 EGF80436.1 - 2.3 8.4 18.0 0.37 11.0 11.6 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus RRN3 PF05327.11 EGF80436.1 - 6.7 5.1 16.4 9.4 4.6 16.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mitofilin PF09731.9 EGF80436.1 - 8.5 5.1 24.8 10 4.8 24.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MGC-24 PF05283.11 EGF80436.1 - 8.5 6.8 17.1 1.9 8.9 9.8 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Macoilin PF09726.9 EGF80436.1 - 8.8 4.8 8.2 9.9 4.6 8.2 1.0 1 0 0 1 1 1 0 Macoilin family PDT PF00800.18 EGF80437.1 - 0.047 13.5 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydratase PDT PF00800.18 EGF80438.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Prephenate dehydratase DDE_Tnp_IS66_C PF13817.6 EGF80438.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 IS66 C-terminal element Shugoshin_C PF07557.11 EGF80439.1 - 0.0096 15.7 0.5 0.035 13.9 0.5 2.1 1 0 0 1 1 1 1 Shugoshin C terminus Pkinase PF00069.25 EGF80440.1 - 1.4e-66 224.6 0.0 1.6e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80440.1 - 2.6e-31 108.9 0.0 3.1e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF80440.1 - 6.2e-05 22.4 0.0 0.00015 21.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGF80440.1 - 0.0042 17.0 0.0 0.029 14.3 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF80440.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm7 PF15585.6 EGF80440.1 - 0.047 14.0 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 7 Pox_ser-thr_kin PF05445.11 EGF80440.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SH3_1 PF00018.28 EGF80442.1 - 5e-10 38.8 0.0 7.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF80442.1 - 5.3e-07 29.4 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF80442.1 - 8.7e-07 28.5 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TTL PF03133.15 EGF80443.1 - 1.7e-86 290.0 0.2 2.1e-86 289.7 0.2 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGF80443.1 - 1.6e-08 34.1 0.1 0.00053 19.3 0.0 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGF80443.1 - 7.2e-05 22.2 0.3 0.0087 15.3 0.0 2.6 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp UPF0564 PF10595.9 EGF80444.1 - 3.4e-12 46.1 33.6 1.7e-06 27.3 21.5 2.6 1 1 0 2 2 2 2 Uncharacterised protein family UPF0564 Pox_RNA_Pol_19 PF05320.12 EGF80444.1 - 0.75 9.7 8.5 0.31 11.0 3.2 2.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit LcrG PF07216.12 EGF80444.1 - 0.78 9.7 4.9 7.7 6.5 0.8 3.1 3 0 0 3 3 3 0 LcrG protein EDR1 PF14381.6 EGF80445.1 - 8e-33 113.8 0.2 1.9e-31 109.3 0.0 2.5 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 Arm PF00514.23 EGF80445.1 - 4.5e-32 109.1 9.2 1.4e-08 34.4 0.0 10.0 9 1 1 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGF80445.1 - 1.7e-16 60.3 10.4 1.6e-05 25.2 0.1 5.6 3 2 1 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 EGF80445.1 - 4.1e-10 39.9 4.6 0.38 11.3 0.0 6.0 5 1 1 6 6 6 4 HEAT-like repeat HEAT PF02985.22 EGF80445.1 - 1.4e-08 34.3 16.9 0.038 14.2 0.0 8.0 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.7 EGF80445.1 - 9.8e-08 32.2 8.4 0.00096 19.2 0.4 4.0 1 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EGF80445.1 - 1.9e-07 31.2 10.2 0.11 12.6 0.1 5.6 3 1 2 6 6 6 2 V-ATPase subunit H Arm_2 PF04826.13 EGF80445.1 - 4.3e-07 29.6 10.6 0.0028 17.1 1.3 3.2 1 1 3 4 4 4 4 Armadillo-like Adaptin_N PF01602.20 EGF80445.1 - 4.4e-07 28.9 6.7 0.0034 16.0 0.0 3.4 1 1 2 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 EGF80445.1 - 0.00019 20.9 3.1 0.11 11.7 0.1 2.6 1 1 1 2 2 2 2 V-ATPase subunit H RICTOR_N PF14664.6 EGF80445.1 - 0.00057 19.0 2.8 0.64 8.9 0.1 3.1 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RTP1_C1 PF10363.9 EGF80445.1 - 0.00065 19.9 3.2 0.11 12.6 0.3 3.8 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 KAP PF05804.12 EGF80445.1 - 0.035 12.3 4.4 0.37 8.9 0.7 2.0 1 1 1 2 2 2 0 Kinesin-associated protein (KAP) NgoMIV_restric PF09015.10 EGF80445.1 - 0.048 12.8 1.5 0.12 11.5 1.6 1.6 1 1 0 1 1 1 0 NgoMIV restriction enzyme CLASP_N PF12348.8 EGF80445.1 - 0.11 12.0 1.4 6.6 6.2 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal DUF3361 PF11841.8 EGF80445.1 - 0.18 11.7 12.4 3.5 7.6 4.0 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF3361) Aconitase_B_N PF11791.8 EGF80445.1 - 0.19 11.8 2.8 16 5.5 0.0 4.1 4 0 0 4 4 4 0 Aconitate B N-terminal domain NopRA1 PF16201.5 EGF80445.1 - 0.38 10.3 1.9 1.8 8.1 0.5 2.6 2 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 MMS19_N PF14500.6 EGF80445.1 - 0.42 10.1 2.0 14 5.2 0.0 3.4 1 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II WAPL PF07814.13 EGF80445.1 - 2.1 7.0 9.7 3 6.6 0.2 3.3 3 0 0 3 3 3 0 Wings apart-like protein regulation of heterochromatin DUF1325 PF07039.11 EGF80446.1 - 1.6e-29 102.7 1.1 2.7e-29 101.9 0.6 1.7 1 1 1 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EGF80446.1 - 5e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EGF80446.1 - 0.041 13.9 0.2 1.8 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 EGF80446.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 AA_permease_2 PF13520.6 EGF80447.1 - 4.6e-57 193.7 37.1 7.4e-57 193.1 36.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF80447.1 - 5.2e-41 140.7 41.5 8.3e-41 140.1 41.5 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGF80447.1 - 1.9e-08 34.3 1.9 1.9e-08 34.3 1.9 3.4 4 0 0 4 4 4 1 C-terminus of AA_permease DUF3087 PF11286.8 EGF80447.1 - 0.75 9.2 0.0 0.75 9.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) AA_permease_2 PF13520.6 EGF80448.1 - 2.2e-55 188.2 43.3 2.8e-55 187.9 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF80448.1 - 7.7e-42 143.5 38.7 1e-41 143.1 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGF80448.1 - 1.4e-06 28.3 1.8 1.4e-06 28.3 1.8 2.9 3 0 0 3 3 3 1 C-terminus of AA_permease EptA_B_N PF08019.12 EGF80448.1 - 0.023 14.6 1.4 0.073 12.9 0.0 2.6 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB AA_permease_2 PF13520.6 EGF80449.1 - 1.9e-56 191.8 42.2 2.3e-56 191.4 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGF80449.1 - 1.1e-42 146.3 38.6 1.6e-42 145.8 38.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EGF80449.1 - 5.9e-07 29.5 3.1 5.9e-07 29.5 3.1 4.2 5 1 0 5 5 5 1 C-terminus of AA_permease Nop52 PF05997.12 EGF80450.1 - 7.1e-48 163.3 2.9 2e-35 122.5 1.3 2.4 1 1 1 2 2 2 2 Nucleolar protein,Nop52 KI67R PF08065.12 EGF80450.1 - 0.11 13.0 11.7 1.3 9.6 6.2 3.0 2 1 1 3 3 3 0 KI67R (NUC007) repeat Ribosomal_L35Ae PF01247.18 EGF80451.1 - 1.8e-43 146.6 0.1 2e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGF80451.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain RIO1 PF01163.22 EGF80452.1 - 1.2e-48 165.2 0.0 2e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EGF80452.1 - 7.7e-35 119.0 0.2 1.5e-34 118.0 0.2 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EGF80452.1 - 1.4e-09 38.2 0.6 0.00022 21.2 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGF80452.1 - 6.5e-05 22.4 0.0 0.009 15.4 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_ScpB PF04079.16 EGF80452.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Prefoldin PF02996.17 EGF80453.1 - 2.5e-23 82.2 2.5 3.1e-23 82.0 2.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGF80453.1 - 0.00022 21.1 7.7 0.00046 20.1 3.8 2.5 1 1 1 2 2 2 1 Prefoldin subunit DUF4347 PF14252.6 EGF80453.1 - 0.01 15.7 0.1 0.016 15.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) GCN5L1 PF06320.13 EGF80453.1 - 0.027 14.6 1.5 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Glutaredoxin2_C PF04399.13 EGF80453.1 - 0.068 13.0 1.8 1.9 8.3 0.2 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain NPV_P10 PF05531.12 EGF80453.1 - 0.092 13.2 1.7 0.34 11.4 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_S6 PF01250.17 EGF80454.1 - 9.2e-22 77.1 0.2 3.9e-21 75.1 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S6 Nop14 PF04147.12 EGF80455.1 - 1.5e-261 870.5 39.5 1.7e-261 870.3 39.5 1.0 1 0 0 1 1 1 1 Nop14-like family CEP170_C PF15308.6 EGF80457.1 - 0.00015 20.5 0.5 0.00019 20.2 0.5 1.0 1 0 0 1 1 1 1 CEP170 C-terminus DHR10 PF18595.1 EGF80457.1 - 0.011 15.7 2.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Zw10 PF06248.13 EGF80457.1 - 0.037 12.6 0.1 0.042 12.4 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Val_tRNA-synt_C PF10458.9 EGF80457.1 - 0.25 11.7 0.2 0.25 11.7 0.2 2.3 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm ATG16 PF08614.11 EGF80457.1 - 1.6 8.9 7.9 5.3 7.2 6.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GSH_synth_ATP PF03917.17 EGF80458.1 - 3e-122 408.0 0.0 3.4e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGF80458.1 - 1.3e-36 125.2 0.2 2.7e-36 124.1 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase BLUF PF04940.12 EGF80459.1 - 0.0012 18.9 0.1 0.0043 17.1 0.0 2.0 2 1 0 2 2 2 1 Sensors of blue-light using FAD DUF1779 PF08680.10 EGF80459.1 - 0.061 13.5 0.4 0.34 11.1 0.2 2.0 2 0 0 2 2 2 0 TATA-box binding Prp19 PF08606.11 EGF80460.1 - 1.7e-31 108.0 1.4 1.7e-31 108.0 1.4 2.0 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 EGF80460.1 - 3.8e-14 52.9 14.3 6.5e-06 26.8 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80460.1 - 3.3e-06 27.3 0.3 0.16 12.3 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 EGF80460.1 - 0.00069 19.7 0.1 0.002 18.3 0.0 1.9 2 0 0 2 2 2 1 U-box domain Cytochrom_D1 PF02239.16 EGF80460.1 - 0.028 13.0 0.0 0.19 10.2 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF1513 PF07433.11 EGF80460.1 - 0.05 12.7 0.0 0.31 10.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Big_7 PF17957.1 EGF80460.1 - 0.14 12.9 1.6 5.8 7.7 0.1 3.3 2 1 1 3 3 3 0 Bacterial Ig domain GreA_GreB_N PF03449.15 EGF80460.1 - 0.21 11.8 1.6 0.86 9.8 0.1 2.6 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal WD40 PF00400.32 EGF80461.1 - 1.1e-48 162.1 26.9 1.3e-09 38.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80461.1 - 5.2e-11 42.7 2.1 0.11 12.9 0.1 4.9 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EGF80461.1 - 0.00038 19.7 0.0 0.37 9.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) PD40 PF07676.12 EGF80461.1 - 0.00058 19.7 1.6 5.3 7.1 0.0 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EGF80461.1 - 0.00059 18.6 9.1 0.0024 16.6 0.2 4.5 3 3 2 6 6 6 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF80461.1 - 0.0013 17.8 0.1 6.9 5.5 0.0 4.0 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGF80461.1 - 0.018 13.6 0.0 0.58 8.6 0.1 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1416 PF07210.12 EGF80461.1 - 0.051 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) WD40_like PF17005.5 EGF80461.1 - 0.19 11.0 0.0 17 4.6 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain zf-C2H2_4 PF13894.6 EGF80462.1 - 4.8e-06 27.0 24.1 0.12 13.2 0.7 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF80462.1 - 2.5e-05 24.5 25.5 0.058 13.9 0.9 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGF80462.1 - 0.0047 17.2 3.8 0.0047 17.2 3.8 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EGF80462.1 - 0.01 16.3 3.7 0.01 16.3 3.7 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2HE PF16278.5 EGF80462.1 - 0.87 10.1 17.2 0.81 10.2 2.1 3.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 EGF80462.1 - 1.9 8.6 19.0 6.4 6.9 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGF80462.1 - 2.1 8.2 14.9 8 6.3 5.5 3.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EGF80462.1 - 4.7 7.7 14.7 21 5.7 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Vps51 PF08700.11 EGF80463.1 - 5.8e-23 80.8 1.3 1.7e-22 79.2 1.3 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 EGF80463.1 - 8.9e-15 55.0 1.1 1.8e-14 54.0 0.1 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 EGF80463.1 - 4.7e-12 45.3 1.8 1.1e-11 44.0 1.8 1.6 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 EGF80463.1 - 0.00014 21.3 3.7 0.00036 19.9 3.7 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 EGF80463.1 - 0.012 15.8 3.1 0.036 14.2 0.7 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Zw10 PF06248.13 EGF80463.1 - 0.015 13.9 2.5 0.036 12.6 2.5 1.6 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG2 PF06148.11 EGF80463.1 - 0.015 15.4 1.4 0.061 13.4 0.2 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 EGF80463.1 - 0.056 12.4 3.1 0.12 11.3 3.1 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal G-patch PF01585.23 EGF80464.1 - 1.7e-11 43.8 5.0 3.9e-11 42.7 5.0 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 EGF80464.1 - 6.2e-06 26.4 2.9 1.5e-05 25.1 2.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 EGF80464.1 - 2.9e-05 24.0 0.5 0.00036 20.5 0.2 2.6 2 0 0 2 2 2 1 G-patch domain zf-met PF12874.7 EGF80464.1 - 0.0003 21.1 0.8 0.00064 20.0 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGF80464.1 - 0.007 16.7 2.3 0.014 15.7 2.3 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 EGF80464.1 - 0.024 14.9 6.4 0.044 14.0 6.4 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 EGF80464.1 - 0.15 12.6 0.8 0.31 11.6 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Mon2_C PF16206.5 EGF80465.1 - 7.7e-61 206.2 6.6 3.6e-32 111.4 6.4 3.6 2 2 0 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 EGF80465.1 - 4.1e-54 182.9 0.5 4.1e-54 182.9 0.5 2.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGF80465.1 - 7e-43 146.3 6.6 7e-43 146.3 6.6 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGF80465.1 - 0.0016 18.2 0.2 0.014 15.2 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) LETM1 PF07766.13 EGF80466.1 - 1.9e-12 47.1 0.1 2.7e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 LETM1-like protein DUF2207 PF09972.9 EGF80466.1 - 0.023 13.5 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Synaptobrevin PF00957.21 EGF80467.1 - 4.2e-34 116.2 3.2 4.9e-34 116.0 3.2 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 EGF80467.1 - 0.0015 18.7 0.3 0.0016 18.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 EGF80467.1 - 0.15 11.6 3.3 0.055 13.0 0.9 1.5 1 1 1 2 2 2 0 fzo-like conserved region Transthyretin PF00576.21 EGF80469.1 - 3.8e-34 117.7 0.0 4.3e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family GCD14_N PF14801.6 EGF80469.1 - 0.018 14.9 0.3 0.042 13.7 0.1 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term HNH_2 PF13391.6 EGF80470.1 - 1.2e-05 25.3 0.0 4.2e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease OSTMP1 PF09777.9 EGF80470.1 - 0.025 14.0 0.2 0.053 12.9 0.2 1.5 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor HNH_2 PF13391.6 EGF80471.1 - 2.2e-05 24.5 0.1 7.8e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease OSTMP1 PF09777.9 EGF80471.1 - 0.035 13.5 0.3 0.065 12.6 0.3 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor vATP-synt_E PF01991.18 EGF80473.1 - 2.9e-62 209.6 10.5 3.4e-62 209.4 10.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Cytochrome_cB PF11783.8 EGF80473.1 - 0.083 12.8 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c bacterial DUF4889 PF16230.5 EGF80473.1 - 0.25 11.6 1.5 0.55 10.5 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) RapH_N PF18801.1 EGF80473.1 - 1.6 8.8 8.2 0.38 10.9 1.0 3.1 3 1 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal RNB PF00773.19 EGF80474.1 - 3.3e-99 332.3 0.0 5.5e-99 331.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EGF80474.1 - 6.3e-21 74.2 0.0 1.3e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGF80474.1 - 6.9e-15 55.5 0.3 2.8e-14 53.5 0.3 2.1 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 EGF80474.1 - 4.5e-13 49.2 0.0 1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EGF80474.1 - 1e-10 41.4 0.2 3.5e-09 36.5 0.2 2.5 1 1 0 1 1 1 1 S1 domain CSD2 PF17876.1 EGF80474.1 - 4.5e-06 26.7 1.0 5.6e-05 23.2 0.0 3.2 4 0 0 4 4 4 1 Cold shock domain EF-hand_1 PF00036.32 EGF80475.1 - 6e-34 113.1 19.0 1.9e-08 33.2 0.4 4.4 5 0 0 5 5 4 4 EF hand EF-hand_7 PF13499.6 EGF80475.1 - 1.2e-31 108.9 5.0 3.7e-16 59.3 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGF80475.1 - 2.2e-28 95.7 6.8 1.4e-08 34.0 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGF80475.1 - 2.8e-23 81.5 12.1 2.3e-11 43.4 0.9 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGF80475.1 - 1.2e-21 75.2 15.4 2.4e-07 29.9 0.1 4.6 5 0 0 5 5 4 4 EF hand EF-hand_9 PF14658.6 EGF80475.1 - 2.5e-10 40.5 0.4 7.9e-07 29.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGF80475.1 - 2.3e-08 34.3 0.4 0.00053 20.3 0.1 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGF80475.1 - 8.2e-07 28.9 1.5 0.017 15.1 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EGF80475.1 - 8.7e-05 22.5 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EGF80475.1 - 0.0004 20.5 2.2 0.4 10.9 0.0 3.4 2 2 1 3 3 3 2 Dockerin type I domain dCache_2 PF08269.11 EGF80475.1 - 0.00063 19.0 0.2 0.64 9.1 0.1 2.0 1 1 1 2 2 2 2 Cache domain RNA_pol_Rpb4 PF03874.16 EGF80475.1 - 0.0012 19.2 5.3 0.16 12.3 0.1 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 EF-hand_11 PF08976.11 EGF80475.1 - 0.0019 19.1 0.1 2.7 8.9 0.0 2.1 1 1 0 2 2 2 2 EF-hand domain Phage_TAC_12 PF12363.8 EGF80475.1 - 0.0026 18.1 2.3 0.21 12.0 0.2 2.5 2 1 1 3 3 3 1 Phage tail assembly chaperone protein, TAC DUF3349 PF11829.8 EGF80475.1 - 0.0032 18.2 1.3 2.1 9.2 0.0 2.5 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) TerB PF05099.13 EGF80475.1 - 0.004 17.1 1.5 0.4 10.6 0.0 2.5 2 1 1 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.13 EGF80475.1 - 0.0058 16.6 6.1 5.8 6.8 0.0 3.9 1 1 3 4 4 4 1 Caleosin related protein DUF5580 PF17743.1 EGF80475.1 - 0.0086 14.7 0.0 0.0093 14.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) YqeY PF09424.10 EGF80475.1 - 0.012 15.7 2.5 0.061 13.4 2.2 2.0 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 EGF80475.1 - 0.013 15.3 2.5 0.5 10.2 0.5 2.1 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 EGF80475.1 - 0.024 15.0 0.6 3.9 7.9 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Glycos_trans_3N PF02885.17 EGF80475.1 - 0.052 13.4 5.4 2.1 8.3 0.1 3.7 3 1 1 4 4 4 0 Glycosyl transferase family, helical bundle domain Peptidase_M24 PF00557.24 EGF80475.1 - 0.061 13.0 0.2 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase family M24 DUF1296 PF06972.11 EGF80475.1 - 0.08 13.1 1.6 3.9 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF1722 PF08349.11 EGF80475.1 - 0.1 12.9 0.0 6.8 7.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) Alpha-2-MRAP_C PF06401.11 EGF80475.1 - 0.11 12.5 1.2 0.12 12.3 0.2 1.6 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain FGAR-AT_linker PF18072.1 EGF80475.1 - 0.12 12.9 0.7 1.6 9.3 0.1 2.7 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Fe_hyd_lg_C PF02906.14 EGF80475.1 - 1 9.0 4.9 9.5 5.8 4.9 2.3 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Pro_dh PF01619.18 EGF80476.1 - 2.1e-64 217.9 0.0 2.4e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase LRR_9 PF14580.6 EGF80476.1 - 0.16 11.4 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeat SMC_N PF02463.19 EGF80477.1 - 1.1e-64 217.9 0.0 2e-64 217.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGF80477.1 - 1.5e-26 93.0 0.1 6.1e-26 91.0 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGF80477.1 - 4.3e-16 59.6 2.1 5.4e-09 36.3 0.3 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF80477.1 - 8.7e-12 46.0 17.0 8.7e-12 46.0 17.0 6.2 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 EGF80477.1 - 2.9e-07 30.5 16.7 2.9e-07 30.5 16.7 4.3 1 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EGF80477.1 - 5.7e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGF80477.1 - 0.00069 19.8 0.2 0.013 15.8 0.0 3.2 4 0 0 4 4 4 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EGF80477.1 - 0.086 13.3 0.0 0.086 13.3 0.0 5.8 3 2 0 3 3 3 0 ABC transporter AAA_22 PF13401.6 EGF80477.1 - 4 7.7 7.6 15 5.9 0.0 4.7 4 1 1 5 5 5 0 AAA domain EF-hand_1 PF00036.32 EGF80478.1 - 9.2e-43 140.6 13.6 1.8e-10 39.6 1.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGF80478.1 - 2.3e-36 124.1 3.2 1e-18 67.6 1.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGF80478.1 - 2.8e-31 104.7 7.1 1.6e-09 37.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGF80478.1 - 4.2e-31 106.6 12.1 1.1e-14 54.0 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGF80478.1 - 9.9e-28 94.4 9.7 1.2e-06 27.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGF80478.1 - 3.9e-16 59.1 0.2 3e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGF80478.1 - 3.8e-10 39.7 1.1 5e-05 23.2 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGF80478.1 - 1.1e-08 35.4 0.1 0.0014 19.0 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGF80478.1 - 5.7e-07 30.4 0.0 0.00032 21.5 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EGF80478.1 - 2.2e-05 24.4 1.6 0.052 13.6 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGF80478.1 - 0.00018 21.5 1.4 0.00067 19.7 0.2 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 EGF80478.1 - 0.0003 21.2 0.0 0.62 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) Dockerin_1 PF00404.18 EGF80478.1 - 0.0005 20.2 6.9 0.021 15.0 0.4 3.3 2 1 3 5 5 4 2 Dockerin type I domain Caleosin PF05042.13 EGF80478.1 - 0.0016 18.4 1.2 0.89 9.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 EGF80478.1 - 0.0017 19.1 0.4 2.3 9.1 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF1103 PF06513.11 EGF80478.1 - 0.0018 18.0 3.4 0.0021 17.7 3.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Poly_export PF02563.16 EGF80478.1 - 0.0021 18.2 0.2 0.86 9.9 0.0 3.5 1 1 3 4 4 4 1 Polysaccharide biosynthesis/export protein TerB PF05099.13 EGF80478.1 - 0.0024 17.9 1.9 0.73 9.8 0.3 2.7 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EGF80478.1 - 0.0028 18.0 0.4 1.7 9.0 0.1 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 EGF80478.1 - 0.01 16.0 0.4 0.15 12.2 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5580 PF17743.1 EGF80478.1 - 0.01 14.4 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EGF80478.1 - 0.018 14.9 0.9 0.79 9.6 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 EGF80478.1 - 0.033 13.4 0.2 2.6 7.1 0.1 2.3 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 EGF80478.1 - 0.051 13.9 0.1 12 6.3 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain Spore_III_AB PF09548.10 EGF80478.1 - 0.13 12.3 0.4 0.33 11.1 0.4 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) SapB_1 PF05184.15 EGF80478.1 - 0.46 10.6 3.5 32 4.7 0.0 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 Pkinase PF00069.25 EGF80480.1 - 2.4e-76 256.6 0.0 3.2e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80480.1 - 6.9e-34 117.3 0.0 9.7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGF80480.1 - 1e-12 48.5 3.3 3.1e-12 47.0 3.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGF80480.1 - 9.6e-06 24.8 0.1 2e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF80480.1 - 8.6e-05 22.0 0.0 0.00046 19.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGF80480.1 - 0.0055 16.3 0.1 0.47 10.1 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Uricase PF01014.18 EGF80481.1 - 5.4e-60 201.4 5.1 6.2e-34 117.1 3.3 2.0 2 0 0 2 2 2 2 Uricase LMWPc PF01451.21 EGF80482.1 - 4.9e-20 72.3 0.0 5.7e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF2779 PF11074.8 EGF80482.1 - 0.028 14.9 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Cyclin_C_2 PF16899.5 EGF80483.1 - 1.1e-17 64.3 0.6 4.1e-16 59.3 0.1 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EGF80483.1 - 2e-06 27.6 0.0 6.6e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain U3snoRNP10 PF12397.8 EGF80484.1 - 0.096 13.0 0.1 0.096 13.0 0.1 4.5 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 10 Robl_LC7 PF03259.17 EGF80485.1 - 1.4e-26 92.1 0.0 1.6e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGF80485.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 EGF80485.1 - 0.012 16.0 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain BrkDBD PF09607.10 EGF80486.1 - 2.3e-05 24.1 0.3 4.8e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_28 PF13518.6 EGF80486.1 - 0.0013 18.8 0.5 0.0022 18.1 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EGF80486.1 - 0.0081 16.4 0.3 0.015 15.6 0.3 1.4 1 0 0 1 1 1 1 Transposase HTH_3 PF01381.22 EGF80486.1 - 0.017 15.2 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 EGF80486.1 - 0.06 13.2 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.13 EGF80486.1 - 0.084 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NTP_transferase PF00483.23 EGF80487.1 - 2.5e-49 168.1 0.0 3.1e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGF80487.1 - 9.4e-13 47.3 5.1 1.7e-10 40.1 2.8 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGF80487.1 - 1.8e-09 38.2 0.0 2.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGF80487.1 - 9.4e-05 22.1 3.7 0.00014 21.5 1.1 2.6 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGF80487.1 - 0.0093 14.2 0.1 0.015 13.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 EGF80487.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NAC PF01849.18 EGF80488.1 - 6.2e-22 77.3 0.1 1.1e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 NAC domain V_ATPase_I PF01496.19 EGF80489.1 - 0 1063.8 4.3 0 1063.7 4.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CheZ PF04344.13 EGF80489.1 - 0.13 12.1 0.6 0.81 9.6 0.1 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Angiomotin_C PF12240.8 EGF80489.1 - 2.3 7.7 5.3 2.5 7.6 2.3 2.0 1 1 0 2 2 2 0 Angiomotin C terminal DUF4246 PF14033.6 EGF80490.1 - 1.2e-82 278.5 0.3 1.5e-82 278.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) CHASE5 PF17149.4 EGF80492.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins TMPIT PF07851.13 EGF80492.1 - 1.1 8.5 6.2 0.095 11.9 1.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein Hydin_ADK PF17213.3 EGF80492.1 - 3.9 7.7 7.8 20 5.4 7.8 2.0 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain ACPS PF01648.20 EGF80493.1 - 5.9e-07 29.6 0.0 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily DUF1126 PF06565.12 EGF80494.1 - 9.2e-97 317.9 5.1 6.8e-36 122.3 0.1 3.1 3 0 0 3 3 3 3 DUF1126 PH-like domain zf-C2HC5 PF06221.13 EGF80495.1 - 2.5e-10 40.2 7.7 4.6e-10 39.3 7.7 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Rap_GAP PF02145.15 EGF80498.1 - 2.1e-41 141.5 0.0 5.7e-41 140.1 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Disaggr_repeat PF06848.11 EGF80498.1 - 0.042 13.5 0.3 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Disaggregatase related repeat 7TMR-HDED PF07697.11 EGF80498.1 - 0.23 11.5 2.7 0.85 9.7 1.3 2.5 2 0 0 2 2 2 0 7TM-HD extracellular UPF0052 PF01933.18 EGF80499.1 - 0.075 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Prefoldin_2 PF01920.20 EGF80500.1 - 2.4e-14 53.1 5.0 3e-14 52.9 5.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin PF00261.20 EGF80500.1 - 0.0063 15.9 5.2 0.26 10.6 1.1 2.0 2 0 0 2 2 2 2 Tropomyosin SNAP PF14938.6 EGF80500.1 - 0.0077 15.7 0.1 0.0095 15.4 0.1 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TACC_C PF05010.14 EGF80500.1 - 0.013 15.3 3.3 0.016 15.0 3.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 EGF80500.1 - 0.049 14.3 3.4 6.1 7.5 0.3 2.7 1 1 2 3 3 3 0 SlyX DUF724 PF05266.14 EGF80500.1 - 0.24 11.2 4.9 2.3 8.0 4.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) NFACT-R_2 PF18297.1 EGF80501.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.6 1 1 1 2 2 2 0 NFACT protein RNA binding domain BAR_2 PF10455.9 EGF80502.1 - 3.1e-41 141.4 0.3 4.4e-41 140.9 0.3 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EGF80502.1 - 6.9e-21 75.0 1.8 1.1e-20 74.4 1.8 1.3 1 1 0 1 1 1 1 BAR domain Transmemb_17 PF09799.9 EGF80503.1 - 1.2e-13 51.5 2.8 1.7e-13 51.1 2.2 1.5 1 1 0 1 1 1 1 Predicted membrane protein TIM21 PF08294.11 EGF80504.1 - 4.4e-09 36.4 0.0 8.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 TIM21 CDC50 PF03381.15 EGF80505.1 - 7.8e-76 255.2 0.1 1e-75 254.9 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family HORMA PF02301.18 EGF80506.1 - 2.3e-59 200.6 0.0 2.7e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain TPR_1 PF00515.28 EGF80507.1 - 0.032 14.0 0.7 6.9 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 EGF80508.1 - 3.7e-22 78.2 0.5 1.3e-21 76.5 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L17 PF01196.19 EGF80508.1 - 0.58 11.1 3.4 1.1 10.2 1.4 2.2 2 0 0 2 2 2 0 Ribosomal protein L17 Glyco_hydro_16 PF00722.21 EGF80509.1 - 5.2e-29 101.0 1.7 8.1e-29 100.3 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_C97 PF05903.14 EGF80510.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Eclosion PF04736.12 EGF80510.1 - 0.042 13.5 0.2 0.07 12.8 0.2 1.3 1 0 0 1 1 1 0 Eclosion hormone LRAT PF04970.13 EGF80510.1 - 0.42 10.9 4.3 0.17 12.2 1.2 2.0 2 1 0 2 2 2 0 Lecithin retinol acyltransferase BTB_3 PF16017.5 EGF80513.1 - 0.016 15.3 0.1 0.039 14.1 0.1 1.8 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF80513.1 - 0.017 15.6 1.9 0.033 14.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) RhoGAP PF00620.27 EGF80517.1 - 1.9e-31 109.0 0.5 8.8e-30 103.5 0.0 2.8 2 0 0 2 2 2 2 RhoGAP domain FF PF01846.19 EGF80518.1 - 1.5e-30 105.1 24.9 1.1e-08 35.1 0.0 6.1 5 0 0 5 5 5 4 FF domain Efg1 PF10153.9 EGF80518.1 - 2.2e-24 86.0 12.1 2.2e-24 86.0 12.1 5.2 5 0 0 5 5 5 1 rRNA-processing protein Efg1 WW PF00397.26 EGF80518.1 - 5.2e-08 32.8 4.0 5e-07 29.7 1.8 2.7 2 0 0 2 2 2 1 WW domain RhoGAP-FF1 PF16512.5 EGF80518.1 - 0.00016 22.3 12.5 0.12 13.0 1.6 4.4 2 1 2 4 4 4 2 p190-A and -B Rho GAPs FF domain DUF4476 PF14771.6 EGF80519.1 - 0.026 14.8 0.0 0.26 11.6 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4476) Pex24p PF06398.11 EGF80519.1 - 0.093 11.7 1.0 0.13 11.2 1.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Kin17_mid PF10357.9 EGF80520.1 - 1.6e-48 163.7 2.0 2.6e-48 163.1 2.0 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EGF80520.1 - 0.011 16.2 6.4 0.022 15.1 6.4 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGF80520.1 - 0.02 15.2 6.1 0.042 14.1 6.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2470 PF10615.9 EGF80520.1 - 0.067 13.8 0.0 0.32 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2470) Tyrosinase PF00264.20 EGF80521.1 - 7.6e-34 117.9 6.4 1e-18 68.5 3.3 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase SAP PF02037.27 EGF80522.1 - 4e-18 64.7 8.5 2.6e-05 23.8 0.0 5.5 5 0 0 5 5 5 4 SAP domain Ydc2-catalyt PF09159.10 EGF80522.1 - 5.6e-10 39.4 1.1 5.6e-10 39.4 1.1 4.3 3 2 0 3 3 3 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EGF80522.1 - 0.00069 19.8 1.5 1.4 9.0 0.1 3.4 3 0 0 3 3 3 2 Poxvirus A22 protein Rho_N PF07498.12 EGF80522.1 - 0.027 14.4 0.4 8 6.5 0.1 3.0 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Mu-like_Pro PF10123.9 EGF80522.1 - 4.2 6.8 5.6 0.94 9.0 0.2 2.6 3 1 1 4 4 4 0 Mu-like prophage I protein B12D PF06522.11 EGF80523.1 - 2.6e-15 56.0 0.1 3.2e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ndc1_Nup PF09531.10 EGF80523.1 - 0.017 13.8 0.0 0.021 13.5 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4257 PF14074.6 EGF80523.1 - 0.094 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) Acyltransferase PF01553.21 EGF80524.1 - 1.2e-10 41.2 0.0 7.9e-10 38.5 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase DCX PF03607.17 EGF80524.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Doublecortin DUF4220 PF13968.6 EGF80524.1 - 0.48 9.8 5.8 0.74 9.1 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DnaJ PF00226.31 EGF80525.1 - 6e-22 77.5 2.4 4.9e-21 74.6 0.3 2.6 2 0 0 2 2 2 1 DnaJ domain DUF2852 PF11014.8 EGF80525.1 - 0.25 11.5 4.9 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Abhydrolase_3 PF07859.13 EGF80526.1 - 8e-12 45.5 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGF80526.1 - 1.7e-06 27.2 0.0 2.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGF80526.1 - 1.2e-05 24.9 0.0 0.00053 19.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGF80526.1 - 0.00014 22.5 0.0 0.00017 22.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF80526.1 - 0.047 12.9 0.3 1.2 8.4 0.0 2.3 2 1 0 2 2 2 0 Serine aminopeptidase, S33 CD225 PF04505.12 EGF80527.1 - 3.1e-06 27.2 0.5 5.8e-06 26.3 0.5 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein DUF4486 PF14858.6 EGF80528.1 - 6.1e-11 41.5 15.0 1.2e-08 34.0 5.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4486) SLBP_RNA_bind PF15247.6 EGF80529.1 - 1e-28 99.2 6.8 1e-28 99.2 6.8 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain DSPc PF00782.20 EGF80532.1 - 2.3e-11 43.7 0.1 7e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF80532.1 - 5.6e-08 32.6 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGF80532.1 - 0.0002 21.1 0.1 0.00051 19.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Ciart PF15673.5 EGF80532.1 - 0.023 14.1 0.3 0.1 12.0 0.1 2.1 2 0 0 2 2 2 0 Circadian-associated transcriptional repressor Y_phosphatase3 PF13350.6 EGF80532.1 - 0.097 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family polyprenyl_synt PF00348.17 EGF80532.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Polyprenyl synthetase AAA_6 PF12774.7 EGF80533.1 - 8.5e-162 537.7 0.0 2.5e-161 536.1 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGF80533.1 - 3.6e-157 524.4 10.2 3.6e-157 524.4 10.2 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGF80533.1 - 2.1e-129 432.1 6.0 2.1e-129 432.1 6.0 3.9 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGF80533.1 - 2.1e-98 328.8 0.0 5.8e-98 327.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGF80533.1 - 1.2e-84 282.9 0.7 6.6e-83 277.2 0.3 3.1 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 EGF80533.1 - 4.9e-84 282.2 0.1 1.9e-83 280.3 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGF80533.1 - 4e-78 261.1 2.0 2.7e-72 242.1 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EGF80533.1 - 3e-54 184.3 10.1 6e-54 183.4 10.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EGF80533.1 - 1.4e-53 181.1 0.4 4.2e-53 179.5 0.4 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGF80533.1 - 1.1e-43 148.1 0.0 2.1e-42 143.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EGF80533.1 - 6.9e-29 100.6 0.4 5.8e-09 36.1 0.0 5.9 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGF80533.1 - 1.4e-23 83.4 0.0 5.3e-23 81.5 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGF80533.1 - 7.5e-17 61.4 2.0 3.6e-16 59.2 0.2 3.2 3 0 0 3 3 2 1 AAA+ lid domain AAA PF00004.29 EGF80533.1 - 7.3e-10 39.4 2.5 0.38 11.2 0.0 6.3 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF80533.1 - 1.9e-07 31.4 9.2 0.037 14.3 0.0 6.0 6 1 0 6 6 5 2 AAA domain AAA_16 PF13191.6 EGF80533.1 - 2.1e-07 31.5 2.9 0.53 10.6 0.0 6.4 5 1 0 5 5 5 1 AAA ATPase domain AAA_30 PF13604.6 EGF80533.1 - 0.00069 19.4 4.3 0.072 12.8 0.1 3.8 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EGF80533.1 - 0.00093 19.4 1.1 8.7 6.5 0.1 4.0 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EGF80533.1 - 0.0026 17.7 1.2 9.3 6.1 0.0 4.0 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_18 PF13238.6 EGF80533.1 - 0.0056 17.2 7.8 2.5 8.7 0.0 5.3 5 1 0 5 5 5 2 AAA domain Sigma54_activat PF00158.26 EGF80533.1 - 0.0062 16.3 0.1 7.9 6.2 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGF80533.1 - 0.035 14.5 0.6 6.6 7.2 0.1 3.3 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 EGF80533.1 - 0.041 12.9 0.1 6 5.8 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_28 PF13521.6 EGF80533.1 - 0.077 13.2 0.3 12 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGF80533.1 - 0.08 12.8 1.0 0.57 10.1 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase DUF853 PF05872.12 EGF80533.1 - 1 7.9 4.9 0.98 7.9 0.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Ribosomal_L24e PF01246.20 EGF80534.1 - 1e-28 99.4 0.2 1e-28 99.4 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF1769 PF08588.10 EGF80535.1 - 6.6e-20 71.1 0.1 1.4e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Oest_recep PF02159.15 EGF80535.1 - 0.78 10.2 3.6 0.41 11.1 1.2 1.7 2 0 0 2 2 2 0 Oestrogen receptor EF-hand_7 PF13499.6 EGF80536.1 - 1.6e-07 31.6 1.3 2.5e-07 31.0 1.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGF80536.1 - 8.6e-07 28.4 2.1 0.0003 20.5 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGF80536.1 - 6.2e-06 25.4 0.6 0.083 12.5 0.0 2.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EGF80536.1 - 9.1e-05 21.8 0.2 0.011 15.2 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGF80536.1 - 0.00049 19.9 0.7 0.0045 16.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGF80536.1 - 0.0015 18.8 0.3 0.048 14.0 0.2 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region CDPS PF16715.5 EGF80536.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 2 0 0 2 2 2 0 Cyclodipeptide synthase S1-P1_nuclease PF02265.16 EGF80537.1 - 2.8e-56 191.2 0.0 3.9e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease Pro_isomerase PF00160.21 EGF80539.1 - 1.7e-42 145.4 0.0 4.5e-42 144.0 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EGF80539.1 - 7.7e-08 32.0 5.4 7.7e-08 32.0 5.4 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EGF80539.1 - 0.00095 19.3 0.1 0.0035 17.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EGF80539.1 - 0.0034 17.5 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 U-box domain Cas6b_N PF17955.1 EGF80539.1 - 0.0054 16.8 0.6 0.015 15.4 0.2 1.9 2 0 0 2 2 2 1 Cas6b N-terminal domain zf-Nse PF11789.8 EGF80539.1 - 0.0073 16.1 0.1 0.06 13.2 0.0 2.5 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DUF4886 PF16227.5 EGF80539.1 - 0.048 12.8 1.5 0.083 12.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) PT-TG PF14449.6 EGF80539.1 - 0.19 11.6 1.2 35 4.4 0.0 3.3 3 0 0 3 3 3 0 Pre-toxin TG DUF5121 PF17165.4 EGF80539.1 - 2 8.9 5.0 1.6 9.2 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5121) CDC45 PF02724.14 EGF80540.1 - 0.24 9.7 13.7 0.42 8.8 13.7 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 EGF80540.1 - 0.78 9.8 20.4 1.6 8.8 20.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YABBY PF04690.13 EGF80540.1 - 3.8 8.0 13.1 4.3 7.9 0.0 2.6 3 0 0 3 3 3 0 YABBY protein RNA_pol_Rpc4 PF05132.14 EGF80540.1 - 5.4 7.4 13.0 0.16 12.4 6.5 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 UCH_1 PF13423.6 EGF80541.1 - 1.3e-82 277.9 0.9 2.6e-82 277.0 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 EGF80541.1 - 4.1e-05 23.2 0.3 0.00015 21.4 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 EGF80541.1 - 0.066 13.5 0.0 16 5.9 0.0 3.3 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF80541.1 - 0.067 12.5 0.5 2.6 7.3 0.1 2.4 2 0 0 2 2 2 0 WD40-like domain HTH_25 PF13413.6 EGF80541.1 - 0.56 10.1 2.0 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain STN1_2 PF09170.10 EGF80542.1 - 1e-08 35.6 3.2 1.6e-08 34.9 3.2 1.3 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Prefoldin PF02996.17 EGF80543.1 - 5.5e-10 39.2 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 EGF80543.1 - 0.00025 21.8 0.1 0.00025 21.8 0.1 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) HEAT PF02985.22 EGF80548.1 - 1.1e-07 31.5 7.0 1.1 9.7 0.0 6.9 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EGF80548.1 - 0.00064 20.3 1.2 0.0077 16.8 0.1 3.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGF80548.1 - 0.00073 19.9 1.2 0.5 10.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats Sec1 PF00995.23 EGF80549.1 - 5.5e-111 372.6 0.0 7.2e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DNA_alkylation PF08713.11 EGF80550.1 - 1.7e-19 70.4 0.0 1.9e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 DNA alkylation repair enzyme DMA PF03474.14 EGF80551.1 - 0.095 12.3 0.2 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 DMRTA motif AAA PF00004.29 EGF80552.1 - 7e-05 23.3 0.0 0.00023 21.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGF80552.1 - 0.0055 16.7 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain DUF2202 PF09968.9 EGF80552.1 - 0.006 16.5 0.0 0.058 13.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein domain (DUF2202) AAA_5 PF07728.14 EGF80552.1 - 0.024 14.7 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF80552.1 - 0.065 13.6 0.1 0.62 10.4 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 EGF80552.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGF80552.1 - 0.11 13.0 0.2 0.7 10.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter GalP_UDP_transf PF01087.22 EGF80553.1 - 1.1e-55 188.9 0.2 2e-55 188.1 0.2 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EGF80553.1 - 3.9e-52 176.3 0.0 8.3e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EGF80553.1 - 0.0097 14.8 0.0 0.029 13.2 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4921) HIT PF01230.23 EGF80553.1 - 0.017 15.9 1.0 0.054 14.2 1.0 1.8 1 1 0 1 1 1 0 HIT domain Img2 PF05046.14 EGF80555.1 - 1.6e-13 50.7 0.0 3.8e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) GATA PF00320.27 EGF80555.1 - 5.8e-12 45.0 4.2 1.5e-11 43.7 4.2 1.8 1 0 0 1 1 1 1 GATA zinc finger PP2C PF00481.21 EGF80556.1 - 7.4e-29 101.2 0.0 9.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ATP-synt_ab_C PF00306.27 EGF80556.1 - 0.096 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Glycos_transf_2 PF00535.26 EGF80557.1 - 2.5e-33 115.3 0.0 3.1e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGF80557.1 - 4.7e-12 46.3 0.0 6.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGF80557.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF80557.1 - 0.0051 16.3 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Phage_Orf51 PF06194.11 EGF80557.1 - 0.14 12.2 0.1 0.53 10.3 0.1 2.0 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 zf-CCHC_3 PF13917.6 EGF80558.1 - 2.1e-14 53.2 4.4 5.6e-14 51.8 4.4 1.8 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 EGF80558.1 - 0.033 14.6 0.1 0.033 14.6 0.1 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 EGF80558.1 - 0.049 13.4 1.2 0.093 12.5 1.2 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Menin PF05053.13 EGF80558.1 - 0.12 10.7 16.8 0.13 10.6 16.8 1.1 1 0 0 1 1 1 0 Menin SPX PF03105.19 EGF80558.1 - 0.41 10.5 33.1 0.49 10.3 33.1 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EGF80558.1 - 0.76 8.3 34.0 0.97 7.9 34.0 1.2 1 0 0 1 1 1 0 Macoilin family DEC-1_N PF04625.13 EGF80559.1 - 2.9 6.8 3.9 3.3 6.6 3.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAML PF14963.6 EGF80560.1 - 3 7.9 9.8 0.65 10.1 1.3 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF4834 PF16118.5 EGF80560.1 - 9.9 7.2 5.6 72 4.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DASH_Dad3 PF08656.10 EGF80561.1 - 0.044 13.9 0.3 0.12 12.5 0.3 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad3 TMEM51 PF15345.6 EGF80561.1 - 0.053 13.4 3.6 0.12 12.2 3.6 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 FAM184 PF15665.5 EGF80561.1 - 0.13 12.0 7.2 0.036 13.8 1.1 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B HR1 PF02185.16 EGF80562.1 - 0.012 15.7 0.5 0.028 14.5 0.5 1.7 1 0 0 1 1 1 0 Hr1 repeat Phage_HK97_TLTM PF06120.11 EGF80562.1 - 0.025 13.8 1.1 0.036 13.3 1.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Spc7 PF08317.11 EGF80562.1 - 1.2 8.0 7.9 0.077 11.9 2.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 EGF80562.1 - 2.5 8.4 9.3 1.1 9.5 3.5 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LMBR1 PF04791.16 EGF80562.1 - 4.5 6.1 4.1 4.5 6.1 3.0 1.4 1 1 1 2 2 2 0 LMBR1-like membrane protein Striatin PF08232.12 EGF80562.1 - 9 6.9 11.0 0.69 10.5 1.5 2.2 2 0 0 2 2 2 0 Striatin family Fibrinogen_BP PF08017.11 EGF80564.1 - 0.013 14.0 7.4 0.018 13.5 7.4 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein ORC6 PF05460.13 EGF80565.1 - 8.9 5.5 7.8 11 5.2 7.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PAG PF15347.6 EGF80566.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched MOZ_SAS PF01853.18 EGF80572.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.0 1 0 0 1 1 1 0 MOZ/SAS family MOZ_SAS PF01853.18 EGF80576.1 - 0.0033 17.1 0.0 0.0033 17.1 0.0 1.0 1 0 0 1 1 1 1 MOZ/SAS family PAG PF15347.6 EGF80577.1 - 0.13 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched ADIP PF11559.8 EGF80580.1 - 0.43 10.7 8.9 0.71 9.9 0.2 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Med6 PF04934.14 EGF80581.1 - 0.059 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 MED6 mediator sub complex component DUF4838 PF16126.5 EGF80581.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) ERM PF00769.19 EGF80582.1 - 0.0073 16.1 9.4 0.0073 16.1 9.4 4.7 3 2 1 4 4 4 2 Ezrin/radixin/moesin family ATG16 PF08614.11 EGF80582.1 - 0.19 11.9 74.2 0.22 11.7 5.3 6.6 6 1 1 7 7 7 0 Autophagy protein 16 (ATG16) V_ATPase_I_N PF18670.1 EGF80582.1 - 0.3 11.5 1.7 12 6.3 0.4 2.9 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain CTD_bind PF04818.13 EGF80583.1 - 2.9e-17 63.3 0.0 7.3e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 EGF80583.1 - 0.00033 20.8 2.6 0.0007 19.8 2.1 1.7 1 1 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTK3 PF12243.8 EGF80583.1 - 0.00095 19.2 0.1 0.003 17.6 0.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 DUF416 PF04222.12 EGF80583.1 - 0.15 11.4 5.3 0.031 13.7 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Fib_alpha PF08702.10 EGF80583.1 - 0.38 10.9 3.8 0.87 9.8 3.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EGF80583.1 - 0.92 10.2 3.7 0.46 11.1 1.0 1.9 2 0 0 2 2 2 0 SlyX Ribosomal_L7Ae PF01248.26 EGF80584.1 - 4.5e-26 90.4 0.3 6.9e-26 89.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAC3 PF12209.8 EGF80584.1 - 0.074 13.2 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain ING PF12998.7 EGF80585.1 - 3.7e-15 56.4 1.9 1.5e-06 28.7 1.9 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGF80585.1 - 1.8e-05 24.5 8.9 3.1e-05 23.8 8.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGF80585.1 - 0.0096 16.1 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C4pol PF14260.6 EGF80585.1 - 0.6 10.6 3.4 0.74 10.3 0.5 2.5 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Pkinase PF00069.25 EGF80587.1 - 5.5e-12 45.6 0.0 2e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF80587.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HSDR_N PF04313.14 EGF80587.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.22 EGF80587.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF80587.1 - 0.0068 15.8 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF80587.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EGF80587.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF80587.1 - 0.022 13.6 0.6 0.032 13.0 0.6 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF80587.1 - 0.025 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF80587.1 - 0.064 12.8 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF80587.1 - 0.18 11.7 0.2 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DnaJ-X PF14308.6 EGF80588.1 - 4.4e-31 108.0 2.5 1.8e-29 102.7 2.5 2.2 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF80588.1 - 2.7e-23 81.8 1.0 7e-23 80.5 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain SMAP PF15477.6 EGF80588.1 - 0.33 12.0 2.8 0.39 11.7 0.3 2.3 3 0 0 3 3 3 0 Small acidic protein family AAA_22 PF13401.6 EGF80589.1 - 0.038 14.3 0.0 0.54 10.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGF80590.1 - 5.5e-12 45.6 0.0 2e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF80590.1 - 7.3e-05 22.8 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF80590.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF80590.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF80590.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF80590.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF80590.1 - 0.023 13.5 0.5 0.031 13.1 0.5 1.3 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF80590.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF80590.1 - 0.065 12.8 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF80590.1 - 0.18 11.7 0.4 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DnaJ-X PF14308.6 EGF80591.1 - 4.7e-31 107.9 2.5 1.8e-29 102.7 2.5 2.2 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF80591.1 - 2.8e-23 81.8 1.0 7e-23 80.5 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain SMAP PF15477.6 EGF80591.1 - 0.31 12.0 2.6 0.39 11.7 0.3 2.3 3 0 0 3 3 3 0 Small acidic protein family Arm_vescicular PF18770.1 EGF80595.1 - 0.41 10.6 3.9 0.46 10.5 0.6 2.1 1 1 1 2 2 2 0 Armadillo tether-repeat of vescicular transport factor HSDR_N PF04313.14 EGF80597.1 - 6e-05 23.1 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) AAA_22 PF13401.6 EGF80599.1 - 0.0029 17.9 0.0 0.022 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF80600.1 - 0.0026 18.0 0.0 0.02 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF80602.1 - 0.0025 18.1 0.0 0.022 15.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain UCH PF00443.29 EGF80603.1 - 2.7e-14 53.3 0.0 9.7e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pro_isomerase PF00160.21 EGF80604.1 - 6.4e-50 169.5 0.0 7.1e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 EGF80604.1 - 0.036 14.4 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain Catalase PF00199.19 EGF80605.1 - 8.5e-168 558.4 0.2 1.1e-167 558.1 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGF80605.1 - 3.8e-20 71.9 0.1 1e-19 70.5 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Aa_trans PF01490.18 EGF80606.1 - 1.1e-07 31.0 25.8 1.1e-07 31.0 25.8 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein 4HB_MCP_1 PF12729.7 EGF80606.1 - 0.0078 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction WD40 PF00400.32 EGF80608.1 - 1.3e-15 57.5 6.6 0.47 11.4 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80608.1 - 1.4e-07 31.7 0.0 0.029 14.7 0.0 4.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF80608.1 - 0.0015 18.0 0.7 0.02 14.2 0.4 2.3 1 1 0 1 1 1 1 WD40-like domain POP1 PF06978.11 EGF80609.1 - 6.4e-40 137.3 18.8 1.6e-20 74.0 3.5 2.6 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGF80609.1 - 5.6e-28 97.1 1.9 1.2e-27 96.1 0.1 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 EGF80609.1 - 8.7e-06 25.3 0.0 1.1 8.5 0.0 3.2 3 0 0 3 3 3 3 Aminomethyltransferase folate-binding domain Hist_deacetyl PF00850.19 EGF80610.1 - 1.6e-81 274.2 0.5 3.7e-81 273.0 0.1 1.7 2 0 0 2 2 2 1 Histone deacetylase domain TAF1_subA PF14929.6 EGF80611.1 - 0.00026 20.6 0.2 0.00029 20.4 0.2 1.0 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A Njmu-R1 PF15053.6 EGF80612.1 - 0.009 15.2 0.1 0.0091 15.1 0.1 1.0 1 0 0 1 1 1 1 Mjmu-R1-like protein family Polysacc_deac_1 PF01522.21 EGF80614.1 - 3.2e-21 75.5 0.0 5.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGF80614.1 - 2.7e-16 59.8 56.5 1.6e-07 31.7 12.7 3.4 3 0 0 3 3 3 3 Chitin recognition protein TENA_THI-4 PF03070.16 EGF80615.1 - 0.054 13.3 0.3 0.34 10.7 0.1 2.1 2 1 0 2 2 2 0 TENA/THI-4/PQQC family Exonuc_VII_L PF02601.15 EGF80615.1 - 0.095 12.3 1.3 0.12 12.0 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 EGF80615.1 - 0.19 11.7 4.4 0.37 10.8 4.2 1.6 1 1 0 1 1 1 0 Laminin Domain II MctB PF11382.8 EGF80615.1 - 0.72 9.5 2.5 0.75 9.4 1.7 1.4 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB V_ATPase_I PF01496.19 EGF80615.1 - 2.1 6.1 6.6 2.6 5.9 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2120 PF09893.9 EGF80615.1 - 3.3 7.8 5.4 21 5.2 5.4 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) G-patch PF01585.23 EGF80616.1 - 3.5e-16 58.8 0.5 7.4e-16 57.8 0.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF80616.1 - 8.6e-09 35.4 0.1 2.1e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 G-patch domain DUF87 PF01935.17 EGF80616.1 - 0.12 12.4 1.0 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF5612 PF18462.1 EGF80616.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) Asp PF00026.23 EGF80617.1 - 2.6e-14 53.4 0.5 3.7e-14 52.9 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80617.1 - 3.6e-07 30.1 0.3 1.3e-06 28.2 0.2 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal WDCP PF15390.6 EGF80618.1 - 0.03 12.7 8.0 0.011 14.2 5.2 1.6 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family ING PF12998.7 EGF80618.1 - 0.045 14.3 1.1 0.094 13.3 1.1 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding T3SSipB PF16535.5 EGF80618.1 - 0.11 13.0 2.2 2.2 8.7 0.3 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB Tup_N PF08581.10 EGF80618.1 - 0.31 11.4 5.1 9.5 6.6 0.2 2.4 2 0 0 2 2 2 0 Tup N-terminal KELK PF15796.5 EGF80618.1 - 0.56 10.7 8.5 4.8 7.7 0.7 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 EGF80618.1 - 0.62 9.4 2.4 0.85 8.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 EGF80618.1 - 4.7 6.8 8.4 30 4.2 8.4 2.0 1 1 0 1 1 1 0 GrpE Auxin_canalis PF05703.11 EGF80618.1 - 9.8 6.0 7.3 15 5.4 7.3 1.4 1 1 0 1 1 1 0 Auxin canalisation DUF5598 PF18127.1 EGF80619.1 - 0.022 15.2 0.0 0.027 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) Myelin_PLP PF01275.19 EGF80619.1 - 0.15 11.9 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) LETM1 PF07766.13 EGF80620.1 - 8.4e-97 323.7 3.2 8.4e-97 323.7 3.2 2.4 2 1 1 3 3 3 1 LETM1-like protein EF-hand_7 PF13499.6 EGF80620.1 - 0.046 14.2 0.0 0.27 11.7 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair V_ATPase_I PF01496.19 EGF80620.1 - 0.048 11.6 7.3 0.037 12.0 5.8 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EF-hand_1 PF00036.32 EGF80620.1 - 0.054 13.1 0.1 0.23 11.1 0.1 2.2 2 0 0 2 2 2 0 EF hand HrcA PF01628.21 EGF80620.1 - 0.17 11.8 5.3 0.036 14.0 0.7 2.2 1 1 1 2 2 2 0 HrcA protein C terminal domain Tn7_Tnp_TnsA_C PF08721.11 EGF80620.1 - 0.89 10.2 4.2 14 6.4 0.3 3.8 3 2 1 4 4 4 0 TnsA endonuclease C terminal DUF4094 PF13334.6 EGF80620.1 - 3.2 8.2 6.4 0.99 9.9 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) hDGE_amylase PF14701.6 EGF80620.1 - 3.5 6.6 6.4 5.6 5.9 6.4 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain LMBR1 PF04791.16 EGF80620.1 - 7.3 5.4 7.3 11 4.7 7.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DOT1 PF08123.13 EGF80621.1 - 0.043 13.3 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 Histone methylation protein DOT1 SNARE_assoc PF09335.11 EGF80622.1 - 3.1e-12 47.0 6.3 3.1e-12 47.0 6.3 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein NCA2 PF08637.10 EGF80623.1 - 6.3e-72 242.2 1.1 6.3e-71 238.9 0.4 2.2 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 PI_PP_C PF18365.1 EGF80623.1 - 0.095 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain DUF4378 PF14309.6 EGF80624.1 - 9.5e-05 22.8 0.1 0.00093 19.6 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4378) MPLKIP PF15502.6 EGF80625.1 - 1.6 9.0 18.5 35 4.7 18.5 2.9 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein DUF5578 PF17741.1 EGF80626.1 - 8.7e-80 268.0 0.9 1.7e-54 185.1 0.1 2.7 2 1 1 3 3 3 2 Family of unknown function (DUF5578) Adaptin_N PF01602.20 EGF80626.1 - 0.0054 15.3 0.2 0.0086 14.7 0.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Transgly PF00912.22 EGF80626.1 - 0.053 13.0 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Transglycosylase M-factor PF03855.13 EGF80627.1 - 0.0052 16.9 1.8 0.046 13.9 0.7 2.1 2 0 0 2 2 2 1 M-factor Acyl_transf_3 PF01757.22 EGF80628.1 - 2.6e-11 43.2 8.3 3.7e-11 42.7 8.3 1.2 1 0 0 1 1 1 1 Acyltransferase family Catalase PF00199.19 EGF80629.1 - 1.9e-168 560.5 0.1 2.4e-168 560.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGF80629.1 - 4.4e-20 71.7 0.1 1e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Inositol_P PF00459.25 EGF80630.1 - 4.7e-48 164.1 0.0 6.3e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family LRR_4 PF12799.7 EGF80631.1 - 1.2e-20 73.2 32.1 6.5e-09 35.9 2.9 8.1 3 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF80631.1 - 7.2e-10 38.6 17.7 5.7e-07 29.2 4.6 3.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 EGF80631.1 - 4.5e-09 35.9 26.2 0.003 17.3 6.9 6.3 2 2 5 7 7 7 6 Leucine rich repeat IQ PF00612.27 EGF80631.1 - 3.7e-05 23.1 8.1 0.0085 15.8 0.5 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_1 PF00560.33 EGF80631.1 - 0.0037 17.6 13.0 8.9 7.3 0.2 7.6 6 1 1 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 EGF80631.1 - 0.09 12.9 14.4 21 5.5 0.0 6.4 7 0 0 7 7 7 0 Leucine Rich repeat HCNGP PF07818.13 EGF80632.1 - 4.6e-25 88.1 1.0 2e-24 86.0 0.1 2.4 2 1 1 3 3 3 1 HCNGP-like protein NOP19 PF10863.8 EGF80632.1 - 0.041 13.7 0.2 0.071 12.9 0.2 1.5 1 0 0 1 1 1 0 Nucleolar protein 19 Chitin_bind_4 PF00379.23 EGF80634.1 - 0.94 10.1 7.6 18 6.0 0.1 4.1 5 0 0 5 5 5 0 Insect cuticle protein Arrestin_N PF00339.29 EGF80635.1 - 0.0026 17.8 0.2 0.012 15.7 0.1 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RuBisCO_small PF00101.20 EGF80635.1 - 0.17 11.9 0.8 45 4.1 0.0 3.4 2 1 1 3 3 3 0 Ribulose bisphosphate carboxylase, small chain ERCC3_RAD25_C PF16203.5 EGF80636.1 - 4.1e-105 350.4 0.1 7.1e-105 349.7 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGF80636.1 - 4.9e-36 123.7 0.0 9e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF80636.1 - 6.3e-18 65.4 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF80636.1 - 4.5e-11 43.1 0.0 1.4e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGF80636.1 - 5e-09 35.3 0.0 6.8e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGF80636.1 - 2.2e-06 27.6 0.0 5.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_M36 PF02128.15 EGF80637.1 - 2.3e-132 441.6 0.9 2.8e-132 441.4 0.9 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) BAR_3 PF16746.5 EGF80638.1 - 2.2e-39 135.6 0.4 7.3e-26 91.3 0.1 2.3 1 1 0 2 2 2 2 BAR domain of APPL family PH PF00169.29 EGF80638.1 - 1.1e-17 64.4 1.9 5.8e-16 58.9 0.1 3.1 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 EGF80638.1 - 7.3e-09 36.0 0.2 6.8e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EGF80638.1 - 5.4e-05 23.4 0.7 0.00025 21.3 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGF80638.1 - 0.0013 19.1 2.0 0.0042 17.5 0.6 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_17 PF18012.1 EGF80638.1 - 0.024 14.4 0.1 0.079 12.7 0.1 1.9 1 0 0 1 1 1 0 PH domain DUF1548 PF07579.11 EGF80638.1 - 0.03 14.7 0.2 0.062 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) DUF2117 PF09890.9 EGF80638.1 - 0.13 11.8 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) VASt PF16016.5 EGF80639.1 - 1e-29 103.9 0.7 2e-29 103.0 0.7 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PPR_long PF17177.4 EGF80640.1 - 7.6e-09 35.2 0.2 0.00059 19.3 0.0 2.7 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGF80640.1 - 2.5e-08 33.9 1.3 0.13 12.4 0.1 5.2 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF80640.1 - 2.6e-07 30.7 11.6 0.14 12.3 0.0 6.4 6 1 2 8 8 8 3 PPR repeat family PPR PF01535.20 EGF80640.1 - 3.8e-07 29.9 14.0 0.33 11.3 0.0 8.4 9 0 0 9 9 9 2 PPR repeat DUF3048 PF11258.8 EGF80640.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain APC1_C PF18122.1 EGF80641.1 - 1e-23 84.1 0.1 3.1e-23 82.5 0.1 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EGF80641.1 - 0.00095 19.7 7.7 0.002 18.7 2.8 3.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EGF80641.1 - 0.038 14.4 1.2 15 6.2 0.0 4.0 3 0 0 3 3 3 0 Proteasome/cyclosome repeat TMF_TATA_bd PF12325.8 EGF80642.1 - 1.7 8.9 7.4 0.35 11.1 1.0 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Pkinase_Tyr PF07714.17 EGF80643.1 - 1.4e-42 145.8 0.0 2.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGF80643.1 - 1.4e-29 103.3 0.0 2.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 EGF80643.1 - 2.3e-08 33.7 7.5 0.0023 17.7 1.7 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EGF80643.1 - 4.7e-05 23.7 11.2 0.04 14.4 0.3 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF80643.1 - 0.00083 19.6 5.2 3.6 8.5 0.0 4.8 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 EGF80643.1 - 0.1 12.7 4.2 1.9 8.7 0.4 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Ric8 PF10165.9 EGF80644.1 - 1.1e-81 275.2 0.1 1.6e-81 274.7 0.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn RPAP1_N PF08621.10 EGF80644.1 - 5.8 6.8 9.2 0.76 9.6 4.7 1.9 2 0 0 2 2 2 0 RPAP1-like, N-terminal Chitin_synth_1 PF01644.17 EGF80647.1 - 3.1e-60 202.8 0.0 5e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EGF80647.1 - 3e-30 105.3 1.9 2.1e-22 79.5 0.1 2.5 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 EGF80647.1 - 6.6e-19 67.6 0.0 4.2e-18 65.1 0.0 2.3 3 0 0 3 3 3 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EGF80647.1 - 1.1e-10 41.8 0.1 1.1e-10 41.8 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF80647.1 - 0.0032 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Syntaxin_2 PF14523.6 EGF80648.1 - 5.3e-24 84.5 7.4 1.2e-23 83.4 3.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 EGF80648.1 - 3.6e-05 23.5 12.4 0.00014 21.6 12.4 2.0 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 EGF80648.1 - 0.021 14.6 0.8 3.3 7.5 0.1 2.4 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SNARE PF05739.19 EGF80648.1 - 0.052 13.6 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 SNARE domain DUF4404 PF14357.6 EGF80648.1 - 0.68 10.6 4.7 8.3 7.1 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 EGF80648.1 - 5 7.2 7.9 5.8 7.0 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HSP90 PF00183.18 EGF80649.1 - 1.8e-232 772.8 31.3 2.1e-232 772.6 31.3 1.0 1 0 0 1 1 1 1 Hsp90 protein LOH1CR12 PF10158.9 EGF80649.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.4 3 0 0 3 3 3 0 Tumour suppressor protein SepSecS PF05889.13 EGF80649.1 - 3.7 6.1 6.4 0.28 9.8 0.4 2.1 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DTW PF03942.15 EGF80650.1 - 3.5e-27 95.4 0.0 4.6e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 DTW domain DUF5638 PF18688.1 EGF80650.1 - 0.044 14.1 0.9 0.074 13.4 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5638) ZZ PF00569.17 EGF80651.1 - 7.3e-07 28.9 4.1 1.3e-06 28.1 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EGF80651.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-UBR PF02207.20 EGF80651.1 - 0.11 12.6 3.4 0.36 11.0 3.4 1.8 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) STOP PF05217.12 EGF80652.1 - 0.008 16.5 6.9 0.008 16.5 6.9 1.6 2 0 0 2 2 2 1 STOP protein SspK PF08176.12 EGF80653.1 - 0.14 12.5 3.9 11 6.4 0.1 3.6 4 1 1 5 5 5 0 Small acid-soluble spore protein K family EF-hand_7 PF13499.6 EGF80654.1 - 2.4e-27 95.2 12.1 9.3e-15 54.8 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF80654.1 - 1.6e-26 89.8 15.5 2.4e-07 29.8 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGF80654.1 - 1.7e-21 74.3 14.8 3.1e-07 29.8 0.1 4.5 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGF80654.1 - 8.2e-17 60.8 14.9 5.1e-10 39.0 0.9 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGF80654.1 - 2.4e-11 42.6 16.5 0.0019 17.6 0.1 4.5 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EGF80654.1 - 2.7e-09 37.2 1.0 0.0024 18.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGF80654.1 - 1.9e-07 31.0 7.7 0.0015 18.5 0.2 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EGF80654.1 - 0.004 17.5 2.5 0.23 11.8 0.2 2.3 1 1 1 2 2 2 1 EF-hand domain Caleosin PF05042.13 EGF80654.1 - 0.0065 16.4 2.2 0.45 10.4 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGF80654.1 - 0.0094 16.3 4.7 0.16 12.3 0.5 2.4 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGF80654.1 - 0.08 13.8 0.6 7.2 7.5 0.1 2.3 1 1 0 2 2 2 0 EF-hand domain DUF4476 PF14771.6 EGF80654.1 - 0.18 12.1 1.4 6.5 7.1 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4476) Unstab_antitox PF09720.10 EGF80654.1 - 0.2 11.7 2.7 0.2 11.7 0.3 2.2 2 0 0 2 2 2 0 Putative addiction module component PhetRS_B1 PF18262.1 EGF80654.1 - 0.22 11.8 2.6 0.15 12.3 0.7 1.8 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain DUF1296 PF06972.11 EGF80654.1 - 0.61 10.3 3.6 6.3 7.0 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1296) Com_YlbF PF06133.11 EGF80654.1 - 1.1 9.9 7.6 11 6.7 0.4 2.7 1 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA YolD PF08863.10 EGF80654.1 - 1.2 9.2 6.7 0.56 10.3 1.2 2.8 1 1 1 3 3 3 0 YolD-like protein SMC_N PF02463.19 EGF80655.1 - 6.4e-37 127.1 0.1 7e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF80655.1 - 1.1e-05 25.4 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Rep_4 PF05797.11 EGF80655.1 - 0.051 12.7 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) SbcCD_C PF13558.6 EGF80655.1 - 0.053 13.8 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NUDIX PF00293.28 EGF80656.1 - 4.7e-24 84.9 0.0 6.3e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain GTP_EFTU PF00009.27 EGF80658.1 - 2.6e-59 200.1 0.1 4.6e-59 199.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGF80658.1 - 4.9e-15 55.3 0.0 1.4e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGF80658.1 - 9.5e-09 35.5 0.0 6.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGF80658.1 - 3.4e-07 30.2 0.0 9.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EGF80658.1 - 0.00031 20.5 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EGF80658.1 - 0.066 13.3 0.1 0.26 11.4 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF80658.1 - 0.11 12.3 0.2 0.65 9.9 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Peptidase_S9 PF00326.21 EGF80659.1 - 0.00018 21.1 0.0 0.0002 20.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family PPR PF01535.20 EGF80660.1 - 1.3e-07 31.4 4.2 0.46 10.8 0.0 6.3 7 0 0 7 7 7 2 PPR repeat PPR_2 PF13041.6 EGF80660.1 - 0.00028 21.0 4.8 5.2 7.4 0.0 4.9 4 1 1 5 5 5 2 PPR repeat family TPR_15 PF13429.6 EGF80660.1 - 0.0093 15.2 0.6 4.5 6.4 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF80660.1 - 0.021 15.3 0.1 29 5.3 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGF80660.1 - 0.059 13.0 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 EGF80660.1 - 0.065 13.3 0.1 24 5.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 EGF80660.1 - 0.094 12.4 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 PPR repeat TPR_6 PF13174.6 EGF80660.1 - 0.11 13.2 0.6 34 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5614 PF18474.1 EGF80661.1 - 4.2e-15 55.7 0.0 8.3e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5614) DUF1308 PF07000.11 EGF80661.1 - 6.7e-13 48.9 0.0 3.9e-06 26.9 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1308) DUF3854 PF12965.7 EGF80662.1 - 0.077 13.0 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) RPA_C PF08784.11 EGF80663.1 - 5.7e-14 52.6 1.0 2.1e-13 50.8 1.0 2.0 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGF80663.1 - 7.4e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EGF80663.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Skp1 PF01466.19 EGF80664.1 - 1.2e-25 89.3 1.4 2.5e-25 88.3 1.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGF80664.1 - 3.2e-14 52.8 3.1 5.2e-14 52.2 0.8 2.4 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain UIM PF02809.20 EGF80665.1 - 0.027 14.4 6.0 0.89 9.6 2.0 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Pkinase PF00069.25 EGF80666.1 - 8.3e-60 202.4 0.0 1.1e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80666.1 - 3.9e-34 118.1 0.0 5.6e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF80666.1 - 2.1e-06 27.3 0.0 7.5e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF80666.1 - 0.0022 16.8 0.7 0.016 14.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGF80666.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family COesterase PF00135.28 EGF80667.1 - 5.4e-93 312.6 0.9 6.7e-93 312.3 0.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGF80667.1 - 6.8e-05 22.8 0.1 0.00016 21.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF80667.1 - 0.03 14.9 0.0 0.049 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGF80667.1 - 0.08 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pox_MCEL PF03291.16 EGF80668.1 - 5.9e-84 282.0 0.0 1.2e-83 281.0 0.0 1.5 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EGF80668.1 - 1.7e-11 44.6 0.0 3.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF80668.1 - 4.9e-09 36.2 0.0 8.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF80668.1 - 2.8e-07 31.1 0.0 5.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF80668.1 - 6.4e-06 26.8 0.0 1.4e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF80668.1 - 1.8e-05 24.7 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF80668.1 - 0.0055 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 EGF80668.1 - 0.0056 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.17 EGF80668.1 - 0.096 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CASP_C PF08172.12 EGF80669.1 - 5.9e-65 219.1 5.6 5.9e-65 219.1 5.6 3.8 2 2 0 2 2 2 1 CASP C terminal ZapB PF06005.12 EGF80669.1 - 0.029 14.8 0.3 0.029 14.8 0.3 7.0 4 2 2 6 6 6 0 Cell division protein ZapB DUF5399 PF17377.2 EGF80669.1 - 1.7 8.4 10.7 0.57 10.0 1.5 3.8 2 1 1 3 3 3 0 Family of unknown function (DUF5399) NOT2_3_5 PF04153.18 EGF80670.1 - 3.8e-26 91.7 0.0 4.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RIBIOP_C PF04950.12 EGF80671.1 - 3.4e-92 309.0 0.2 3.4e-92 309.0 0.2 1.8 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGF80671.1 - 8.1e-35 118.8 0.1 6.2e-34 115.9 0.0 2.7 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EGF80671.1 - 0.00065 20.0 0.1 0.0028 18.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EGF80671.1 - 0.00083 19.8 2.2 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF80671.1 - 0.015 15.8 0.3 0.14 12.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGF80671.1 - 0.02 14.9 0.1 0.057 13.5 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGF80671.1 - 0.024 14.4 0.1 0.22 11.3 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGF80671.1 - 0.03 14.7 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EGF80671.1 - 0.031 14.6 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 EGF80671.1 - 0.07 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 EGF80671.1 - 0.076 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF80671.1 - 0.091 13.0 0.7 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGF80671.1 - 0.14 12.6 0.9 0.74 10.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Peptidase_M24 PF00557.24 EGF80672.1 - 3e-44 151.2 0.0 3.7e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 EGF80672.1 - 0.18 12.2 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Fer2 PF00111.27 EGF80672.1 - 0.19 11.7 0.4 0.53 10.3 0.4 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FA_desaturase PF00487.24 EGF80673.1 - 2.7e-17 63.5 20.1 2.7e-17 63.5 20.1 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Phage_int_SAM_4 PF13495.6 EGF80673.1 - 0.017 15.6 1.9 0.047 14.2 0.5 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain EMC3_TMCO1 PF01956.16 EGF80673.1 - 0.04 13.7 1.2 0.12 12.1 1.0 1.9 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like MS_channel PF00924.18 EGF80674.1 - 2.8e-17 63.0 0.0 5.9e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 EGF80674.1 - 0.044 13.7 0.1 0.044 13.7 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain DUF5400 PF17379.2 EGF80674.1 - 0.18 12.3 5.2 0.4 11.2 5.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5400) Sec1 PF00995.23 EGF80675.1 - 2e-103 347.6 0.0 2.3e-103 347.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pribosyl_synth PF14572.6 EGF80675.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain IBN_N PF03810.19 EGF80676.1 - 2.1e-11 43.5 1.3 3.9e-10 39.5 0.5 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 EGF80676.1 - 4.6e-07 29.0 0.0 1.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.6 EGF80676.1 - 0.029 14.8 0.0 9.2 6.7 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EGF80676.1 - 0.045 14.0 1.9 20 5.8 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 EGF80676.1 - 0.048 13.7 0.2 1 9.4 0.1 3.1 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Glyco_hydro_63 PF03200.16 EGF80677.1 - 2.4e-163 544.4 5.8 2.7e-162 540.9 5.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGF80677.1 - 1.1e-62 212.1 0.0 1.8e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EGF80677.1 - 1.3e-06 27.6 0.1 2e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Trehalase Porin_3 PF01459.22 EGF80678.1 - 9.1e-73 245.0 0.8 1e-72 244.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin RelB_transactiv PF16181.5 EGF80678.1 - 0.062 13.6 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 RelB transactivation domain MMS1_N PF10433.9 EGF80679.1 - 1.1e-94 317.8 0.3 1.8e-94 317.1 0.3 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGF80679.1 - 2.9e-73 247.0 0.0 2.8e-70 237.2 0.0 3.7 3 1 0 3 3 3 2 CPSF A subunit region TFIIB PF00382.19 EGF80680.1 - 1.1e-31 108.7 0.9 7.3e-18 64.4 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGF80680.1 - 1.6e-20 73.3 0.7 3.5e-20 72.2 0.7 1.6 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGF80680.1 - 2.1e-07 30.3 2.2 4.7e-07 29.2 2.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EGF80680.1 - 0.006 16.3 0.6 4.2 7.1 0.0 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain Vps36-NZF-N PF16988.5 EGF80680.1 - 0.18 11.2 0.3 0.37 10.2 0.3 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain A2L_zn_ribbon PF08792.10 EGF80680.1 - 1.3 8.8 3.4 12 5.7 3.4 2.3 1 1 0 1 1 1 0 A2L zinc ribbon domain Ribonuc_red_lgC PF02867.15 EGF80682.1 - 7.4e-189 628.6 0.0 9.6e-189 628.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGF80682.1 - 1.1e-23 83.0 0.1 3e-23 81.6 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGF80682.1 - 9.9e-17 61.3 0.0 4.1e-16 59.3 0.0 2.1 1 0 0 1 1 1 1 ATP cone domain Pkinase_Tyr PF07714.17 EGF80683.1 - 3.9e-31 108.3 0.0 6.4e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGF80683.1 - 2.9e-28 99.0 0.0 6.9e-28 97.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 EGF80683.1 - 3.1e-12 46.9 3.9 4.4e-10 40.0 3.9 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF80683.1 - 4.1e-08 33.6 1.5 0.0011 19.5 0.0 3.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF80683.1 - 8.7e-08 32.3 4.0 0.0023 18.2 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGF80683.1 - 9.8e-05 22.6 3.6 0.0021 18.4 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EGF80683.1 - 0.00036 20.8 1.4 0.19 12.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat DUF1843 PF08898.10 EGF80683.1 - 0.0082 16.6 0.7 4.2 7.9 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF1843) Phtf-FEM1B_bdg PF12129.8 EGF80683.1 - 0.042 13.7 0.1 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor zf-CCHC PF00098.23 EGF80684.1 - 7.9e-14 51.0 21.4 0.0005 20.0 0.7 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 EGF80684.1 - 7.6e-08 32.0 24.3 5.8e-05 22.8 2.3 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 EGF80684.1 - 0.00014 21.5 22.2 0.032 14.0 0.5 4.1 4 0 0 4 4 4 3 Zinc knuckle DUF4803 PF16061.5 EGF80684.1 - 0.13 11.7 2.4 0.13 11.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) zf-RING_9 PF13901.6 EGF80684.1 - 0.57 10.1 8.8 3.4 7.6 0.4 2.1 1 1 0 2 2 2 0 Putative zinc-RING and/or ribbon CLAMP PF14769.6 EGF80686.1 - 0.002 18.5 1.7 0.0025 18.2 0.5 1.8 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 HSBP1 PF06825.12 EGF80686.1 - 0.072 13.0 1.1 0.7 9.8 1.5 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PIGA PF08288.12 EGF80688.1 - 1.9e-42 143.7 0.4 5.5e-42 142.3 0.4 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EGF80688.1 - 2.4e-28 98.8 0.0 3.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGF80688.1 - 1e-27 97.2 1.5 1.6e-27 96.6 1.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGF80688.1 - 8.7e-22 78.0 0.1 1.8e-21 76.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGF80688.1 - 1.9e-12 47.9 0.1 3.2e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGF80688.1 - 1.9e-05 25.0 0.0 0.00069 20.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EGF80688.1 - 8.4e-05 22.6 0.1 0.00015 21.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Mito_carr PF00153.27 EGF80689.1 - 6e-55 183.2 1.6 4.3e-19 68.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF80689.1 - 3.7e-05 23.0 1.2 1.3 8.1 0.1 3.4 2 2 0 3 3 3 3 Gammaproteobacterial serine protease zf-H2C2_2 PF13465.6 EGF80690.1 - 2.7e-09 37.0 7.2 1.7e-06 28.2 0.3 3.5 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGF80690.1 - 2.9e-09 36.9 28.7 0.00013 22.2 1.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF80690.1 - 3.6e-08 33.6 24.9 0.0036 18.0 1.0 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGF80690.1 - 0.03 14.3 18.5 0.4 10.8 1.2 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-AN1 PF01428.16 EGF80690.1 - 0.054 13.7 16.0 0.083 13.1 3.3 2.7 1 1 2 3 3 3 0 AN1-like Zinc finger ADK_lid PF05191.14 EGF80690.1 - 0.088 12.8 5.3 0.14 12.2 3.1 2.1 1 1 1 2 2 2 0 Adenylate kinase, active site lid PHD PF00628.29 EGF80690.1 - 0.25 11.2 10.0 0.54 10.2 4.8 2.3 2 0 0 2 2 2 0 PHD-finger zf-met PF12874.7 EGF80690.1 - 0.28 11.6 0.1 0.28 11.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EGF80690.1 - 0.63 10.4 12.0 0.09 13.1 6.2 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon CpXC PF14353.6 EGF80690.1 - 1.1 9.4 4.9 1 9.4 0.3 2.2 1 1 1 2 2 2 0 CpXC protein zf_UBZ PF18439.1 EGF80690.1 - 1.6 8.4 11.2 0.47 10.1 0.3 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger IBR PF01485.21 EGF80690.1 - 2.9 8.2 9.9 0.98 9.7 5.1 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 EGF80690.1 - 3 8.1 8.5 8.1 6.7 0.8 2.9 1 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 EGF80690.1 - 5.5 7.4 12.2 8.2 6.8 1.3 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C5HCH PF17982.1 EGF80690.1 - 6.8 6.9 11.4 7.2 6.9 1.1 2.9 1 1 2 3 3 3 0 NSD Cys-His rich domain NIF PF03031.18 EGF80691.1 - 2e-08 34.2 0.0 2.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGF80691.1 - 0.022 15.2 0.0 2.7 8.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase EamA PF00892.20 EGF80692.1 - 3.7e-21 75.7 34.7 2.3e-11 44.0 13.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLATT_fungal PF18142.1 EGF80692.1 - 1.9 8.5 3.5 4.3 7.3 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Pkinase PF00069.25 EGF80693.1 - 1.3e-68 231.2 0.1 2.2e-68 230.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80693.1 - 4.2e-41 140.9 0.0 8.6e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EGF80693.1 - 4.6e-19 68.0 27.8 1.7e-09 37.4 9.7 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EGF80693.1 - 2.1e-12 47.5 0.4 5.3e-12 46.2 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGF80693.1 - 1.5e-05 24.1 0.1 2.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF80693.1 - 2.5e-05 23.8 0.1 5.1e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 EGF80693.1 - 0.00085 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain C1_2 PF03107.16 EGF80693.1 - 0.00096 19.4 23.7 0.012 15.9 7.7 2.7 2 0 0 2 2 2 2 C1 domain FTA2 PF13095.6 EGF80693.1 - 0.0034 17.0 0.5 0.06 13.0 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF80693.1 - 0.0045 15.8 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase HR1 PF02185.16 EGF80693.1 - 0.088 12.9 0.3 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Hr1 repeat BCIP PF13862.6 EGF80694.1 - 4.3e-66 222.6 3.4 5.1e-66 222.4 3.4 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF1845 PF08900.11 EGF80694.1 - 0.064 13.0 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) UCR_14kD PF02271.16 EGF80695.1 - 1.2e-32 111.8 0.2 1.5e-32 111.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SART-1 PF03343.13 EGF80696.1 - 2.9e-141 472.1 50.8 3.4e-141 471.9 50.8 1.1 1 0 0 1 1 1 1 SART-1 family PB1 PF00564.24 EGF80696.1 - 0.059 13.3 1.6 18 5.4 0.0 3.4 3 0 0 3 3 3 0 PB1 domain DUF3496 PF12001.8 EGF80696.1 - 1.4 9.3 8.2 2.1 8.7 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) Myb_DNA-bind_4 PF13837.6 EGF80697.1 - 0.00011 22.5 4.3 0.00011 22.5 2.4 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EGF80697.1 - 1.1 10.2 5.6 0.41 11.7 1.8 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Tcp11 PF05794.13 EGF80698.1 - 4.8e-28 98.4 0.3 5.3e-28 98.3 0.3 1.0 1 0 0 1 1 1 1 T-complex protein 11 DUF4477 PF14780.6 EGF80699.1 - 0.0004 20.1 6.5 0.0022 17.6 6.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) Ribosomal_60s PF00428.19 EGF80700.1 - 4.5e-28 97.7 8.0 5.5e-28 97.4 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3546 PF12066.8 EGF80701.1 - 3.4e-18 65.8 0.5 9.5e-18 64.4 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EGF80701.1 - 3.2e-15 57.0 1.9 3.9e-15 56.7 0.0 2.2 2 1 0 2 2 2 1 Arsenite-resistance protein 2 RRM_1 PF00076.22 EGF80701.1 - 0.00038 20.2 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.8 EGF80701.1 - 0.015 15.6 0.4 0.015 15.6 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF80701.1 - 0.047 14.1 0.6 0.17 12.4 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF4187 PF13821.6 EGF80701.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) ubiquitin PF00240.23 EGF80702.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EGF80702.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGF80702.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EGF80702.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGF80702.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGF80702.1 - 2.2e-14 53.6 8.0 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 EGF80702.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGF80702.1 - 6.7e-10 39.0 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGF80702.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EGF80702.1 - 5.2e-07 29.2 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EGF80702.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 EGF80702.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 EGF80702.1 - 5.8e-06 26.6 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EGF80702.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 EGF80702.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 EGF80702.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_4 PF13291.6 EGF80702.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 EGF80702.1 - 0.00036 20.0 0.1 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EGF80702.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EGF80702.1 - 0.0069 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EGF80702.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EGF80702.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 EGF80702.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 EGF80702.1 - 0.35 11.4 8.8 51 4.4 1.5 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 EGF80702.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 EGF80702.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EGF80702.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein DAO PF01266.24 EGF80703.1 - 1.2e-49 169.8 0.2 1.7e-49 169.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EGF80703.1 - 1.5e-44 150.9 0.0 2.7e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_1 PF00036.32 EGF80703.1 - 2.9e-11 42.1 4.6 8.6e-05 21.8 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EGF80703.1 - 3.9e-11 43.2 0.1 1e-10 41.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 EGF80703.1 - 1.9e-08 33.9 1.2 3.7e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain EF-hand_6 PF13405.6 EGF80703.1 - 3.1e-08 32.9 0.5 0.00018 21.2 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EGF80703.1 - 8.3e-08 31.4 0.3 0.011 15.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGF80703.1 - 8.6e-08 31.9 1.0 3.1e-07 30.1 0.3 2.4 2 1 1 3 3 3 2 EF-hand domain pair FAD_oxidored PF12831.7 EGF80703.1 - 9.8e-07 28.5 1.7 1.5e-06 27.9 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGF80703.1 - 0.0016 17.7 0.0 0.0038 16.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGF80703.1 - 0.0028 17.0 0.1 0.0098 15.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGF80703.1 - 0.003 17.7 0.1 0.02 15.1 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGF80703.1 - 0.0057 15.4 0.1 0.011 14.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EGF80703.1 - 0.012 14.7 0.2 0.035 13.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGF80703.1 - 0.035 13.4 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF80703.1 - 0.083 13.5 0.1 0.25 11.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGF80703.1 - 0.085 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Thi4 family CM1 PF03026.15 EGF80704.1 - 0.033 13.6 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Influenza C virus M1 protein F-box-like PF12937.7 EGF80705.1 - 2.7e-05 24.0 3.6 2.7e-05 24.0 3.6 2.4 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 EGF80705.1 - 0.89 10.4 7.8 57 4.9 0.6 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat Glyco_trans_2_3 PF13632.6 EGF80706.1 - 4.5e-18 65.9 0.4 4.5e-18 65.9 0.4 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF80706.1 - 0.00024 21.0 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PP2C PF00481.21 EGF80707.1 - 1.4e-82 277.2 0.0 2.2e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGF80707.1 - 0.0031 17.2 0.2 2 8.0 0.1 2.6 1 1 1 2 2 2 2 Protein phosphatase 2C Cu-oxidase PF00394.22 EGF80707.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Cyt-b5 PF00173.28 EGF80708.1 - 3.9e-10 39.7 0.1 4e-10 39.7 0.1 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IPK PF03770.16 EGF80710.1 - 6.2e-38 130.6 0.0 4.5e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase DUF3421 PF11901.8 EGF80711.1 - 2.5e-26 91.9 0.6 4.2e-25 88.0 0.1 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBFD_NFYB_HMF PF00808.23 EGF80712.1 - 4.1e-15 55.8 0.0 7.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGF80712.1 - 3.2e-08 34.0 0.8 1.2e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Cwf_Cwc_15 PF04889.12 EGF80712.1 - 0.003 17.3 1.2 0.0035 17.1 1.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein WDCP PF15390.6 EGF80712.1 - 0.063 11.7 0.4 0.12 10.7 0.0 1.5 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family TetR_C_16 PF17920.1 EGF80713.1 - 0.031 14.5 0.8 0.11 12.7 0.0 2.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Orexin_rec2 PF03827.13 EGF80713.1 - 0.075 13.0 0.2 19 5.4 0.1 2.6 2 0 0 2 2 2 0 Orexin receptor type 2 EutH PF04346.12 EGF80713.1 - 0.086 12.0 0.6 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation protein, EutH DUF2240 PF09999.9 EGF80713.1 - 0.089 12.4 0.6 0.2 11.3 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Transket_pyr PF02779.24 EGF80714.1 - 1.3e-59 200.9 0.0 2e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGF80714.1 - 1.8e-46 157.6 0.0 3.1e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EGF80714.1 - 1.7e-43 148.7 0.0 2.6e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component RRM_1 PF00076.22 EGF80715.1 - 5.8e-15 54.9 0.0 8.1e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGF80715.1 - 9.8e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Transket_pyr PF02779.24 EGF80716.1 - 2.1e-42 144.8 0.1 3.2e-42 144.2 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGF80716.1 - 1.2e-32 112.3 0.0 2.7e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Cellulase PF00150.18 EGF80719.1 - 7.2e-25 88.0 0.2 9.7e-25 87.5 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rax2 PF12768.7 EGF80719.1 - 0.0024 17.3 0.3 0.0084 15.6 0.1 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 EGF80719.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family rve PF00665.26 EGF80719.1 - 0.13 12.4 0.0 0.79 9.9 0.0 2.3 3 0 0 3 3 3 0 Integrase core domain Neur_chan_memb PF02932.16 EGF80719.1 - 0.14 12.2 0.7 0.26 11.3 0.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4481 PF14800.6 EGF80719.1 - 1 8.8 3.1 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) GST_C_3 PF14497.6 EGF80721.1 - 1.6e-15 57.1 0.0 2.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGF80721.1 - 3e-06 27.5 0.0 5.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF80721.1 - 0.00021 21.4 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGF80721.1 - 0.00044 20.6 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGF80721.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGF80721.1 - 0.035 14.8 0.0 0.063 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Elf1 PF05129.13 EGF80722.1 - 0.29 11.2 1.6 0.44 10.6 1.6 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like OrsD PF12013.8 EGF80723.1 - 3.8e-08 33.8 0.8 3.8e-08 33.8 0.8 3.1 2 1 1 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 EGF80723.1 - 0.0023 18.2 6.5 0.27 11.6 0.1 3.5 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) PPS_PS PF02006.16 EGF80723.1 - 0.043 13.4 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase zf-MYST PF17772.1 EGF80723.1 - 0.079 12.6 2.4 0.13 11.9 0.9 2.2 2 0 0 2 2 2 0 MYST family zinc finger domain GPCR_chapero_1 PF11904.8 EGF80723.1 - 0.13 11.7 1.9 0.24 10.8 1.9 1.3 1 0 0 1 1 1 0 GPCR-chaperone zf-C2H2_4 PF13894.6 EGF80723.1 - 0.31 12.0 21.5 3.5 8.7 2.4 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1908 PF08926.11 EGF80723.1 - 1 8.4 7.0 0.43 9.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1908) Gelsolin PF00626.22 EGF80726.1 - 3.3e-28 97.4 0.0 5.6e-09 35.8 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat PseudoU_synth_1 PF01416.20 EGF80727.1 - 3.2e-28 98.3 0.0 1.6e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Glyco_hydro_61 PF03443.14 EGF80728.1 - 0.084 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Peptidase_M50B PF13398.6 EGF80730.1 - 1.8e-57 194.2 11.4 2.2e-57 194.0 11.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like YqhR PF11085.8 EGF80730.1 - 0.48 10.3 10.6 0.39 10.6 8.0 2.0 2 0 0 2 2 2 0 Conserved membrane protein YqhR CbtB PF09489.10 EGF80730.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) PIF1 PF05970.14 EGF80731.1 - 1.3e-10 41.0 0.1 1.9e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EGF80731.1 - 3.5e-08 33.4 0.0 5.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGF80731.1 - 0.00025 21.1 0.4 0.00051 20.0 0.0 1.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGF80731.1 - 0.00056 20.3 1.9 0.0013 19.1 0.4 2.0 1 1 1 2 2 2 1 AAA domain MobB PF03205.14 EGF80731.1 - 0.0042 17.0 0.7 0.024 14.6 0.1 2.3 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EGF80731.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGF80731.1 - 0.0052 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 EGF80731.1 - 0.0073 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DEAD PF00270.29 EGF80731.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 EGF80731.1 - 0.011 14.7 0.4 0.018 14.0 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 EGF80731.1 - 0.012 16.0 0.4 0.79 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EGF80731.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGF80731.1 - 0.032 14.7 0.0 0.032 14.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter cobW PF02492.19 EGF80731.1 - 0.055 13.1 0.9 0.075 12.6 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 EGF80731.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_32 PF13654.6 EGF80731.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGF80731.1 - 0.097 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGF80731.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 EGF80731.1 - 0.18 11.5 2.0 0.24 11.1 0.1 2.1 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Barwin PF00967.17 EGF80732.1 - 5.5e-07 29.5 1.2 1e-06 28.6 0.9 1.6 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 EGF80732.1 - 0.00049 20.2 0.1 0.0014 18.7 0.1 1.7 1 1 1 2 2 2 1 Cerato-platanin CCD48 PF15799.5 EGF80732.1 - 8.6 4.5 10.1 3.8 5.7 8.0 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 Vma12 PF11712.8 EGF80736.1 - 0.1 12.6 0.2 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Y_phosphatase PF00102.27 EGF80737.1 - 3.9e-55 187.0 0.0 2.6e-53 181.0 0.0 2.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGF80737.1 - 0.023 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family LRR_4 PF12799.7 EGF80738.1 - 9.6e-33 111.7 28.0 7.9e-09 35.7 1.1 6.7 4 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF80738.1 - 1e-17 64.2 17.0 6.1e-09 35.6 3.7 3.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 EGF80738.1 - 4.9e-16 58.2 34.0 1e-05 25.2 3.9 6.0 2 1 7 9 9 9 8 Leucine rich repeat LRR_6 PF13516.6 EGF80738.1 - 3.5e-05 23.5 12.0 0.18 11.9 0.1 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EGF80738.1 - 0.0023 18.2 21.0 9.8 7.2 0.1 8.7 8 1 0 8 8 8 2 Leucine Rich Repeat Bromodomain PF00439.25 EGF80739.1 - 4.5e-42 142.0 0.2 1.4e-20 73.1 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EGF80739.1 - 1.5e-20 73.1 1.8 3e-20 72.1 1.8 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation End3 PF12761.7 EGF80739.1 - 0.011 15.9 1.9 0.042 14.0 1.9 2.0 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FlxA PF14282.6 EGF80739.1 - 2 8.5 9.0 0.077 13.0 1.1 2.9 3 0 0 3 3 3 0 FlxA-like protein WD40 PF00400.32 EGF80741.1 - 1.1e-05 26.0 1.8 0.078 13.9 0.0 4.8 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80741.1 - 0.0015 18.8 0.3 5.1 7.5 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF80741.1 - 0.0033 17.3 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A S10_plectin PF03501.15 EGF80742.1 - 3.7e-45 151.9 0.6 4.7e-45 151.6 0.4 1.3 1 1 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EGF80742.1 - 0.0012 18.6 0.3 0.0031 17.3 0.3 1.7 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF1495 PF07381.11 EGF80742.1 - 0.089 12.6 0.1 3.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) DUF2250 PF10007.9 EGF80742.1 - 0.31 11.2 1.8 15 5.8 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) zf-CCCH PF00642.24 EGF80743.1 - 1.6e-12 47.0 15.7 5.1e-07 29.5 2.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EGF80743.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGF80743.1 - 0.00027 20.9 17.3 0.015 15.4 2.9 2.8 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 EGF80743.1 - 0.0004 21.0 4.0 0.3 11.8 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EGF80743.1 - 0.0016 18.7 2.1 0.38 11.0 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger containing family Lebercilin PF15619.6 EGF80744.1 - 6.7e-22 78.1 33.0 6.7e-22 78.1 33.0 1.8 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease fn3 PF00041.21 EGF80744.1 - 2.4e-11 43.8 7.6 0.00052 20.3 0.4 4.4 4 1 0 4 4 4 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EGF80744.1 - 0.00019 22.0 0.0 0.2 12.2 0.0 2.9 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain DUF3866 PF12982.7 EGF80744.1 - 0.028 13.5 0.8 0.059 12.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DUF2369 PF10179.9 EGF80744.1 - 0.32 11.4 1.4 15 6.0 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) DUF1664 PF07889.12 EGF80744.1 - 1.4 9.0 14.9 0.35 10.9 4.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 EGF80744.1 - 2.2 7.6 27.5 1.1 8.6 24.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EGF80744.1 - 4.9 7.3 15.8 1.6 8.9 7.4 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EGF80744.1 - 5.2 6.3 16.5 0.83 9.0 12.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mhr1 PF12829.7 EGF80745.1 - 5.3e-05 23.2 0.0 0.00049 20.1 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination RRS1 PF04939.12 EGF80746.1 - 5.8e-55 185.6 3.5 6.5e-55 185.4 3.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) ThiF PF00899.21 EGF80747.1 - 1.3e-68 231.0 0.0 1.6e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EGF80747.1 - 1.2e-11 45.0 1.7 9.6e-06 25.7 0.1 2.4 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 EGF80747.1 - 3.4e-05 24.3 1.9 3.4e-05 24.3 1.9 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 EGF80747.1 - 0.0036 17.7 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding DUF812 PF05667.11 EGF80747.1 - 0.026 13.4 0.2 0.048 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sacchrp_dh_NADP PF03435.18 EGF80747.1 - 0.045 14.0 0.7 0.39 11.0 0.7 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MRP-S34 PF16053.5 EGF80748.1 - 2.7e-08 33.6 0.0 3.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 AsmA_1 PF13109.6 EGF80749.1 - 0.034 13.6 0.2 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region SPO22 PF08631.10 EGF80752.1 - 1.2e-10 41.4 2.1 1.2e-10 41.4 2.1 2.4 2 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 EGF80752.1 - 0.0025 18.3 1.3 0.077 13.5 0.2 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80752.1 - 0.021 14.9 0.8 32 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80752.1 - 0.078 13.3 1.1 0.34 11.2 0.0 2.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NusG PF02357.19 EGF80752.1 - 0.095 13.2 0.1 5.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Transcription termination factor nusG Methyltransf_28 PF02636.17 EGF80755.1 - 1.5e-70 237.8 0.0 1.8e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DASH_Spc19 PF08287.11 EGF80756.1 - 0.0022 17.9 4.7 0.01 15.7 4.6 1.9 1 1 0 1 1 1 1 Spc19 Phasin PF05597.11 EGF80756.1 - 0.0068 16.4 1.1 0.21 11.6 0.0 2.3 2 1 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) YkyA PF10368.9 EGF80756.1 - 0.023 14.4 4.7 0.029 14.1 4.7 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein AcetDehyd-dimer PF09290.11 EGF80756.1 - 0.024 14.8 0.6 0.04 14.1 0.6 1.3 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation HMMR_N PF15905.5 EGF80756.1 - 0.027 13.9 5.1 0.014 14.9 3.0 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Relaxase PF03432.14 EGF80756.1 - 0.033 13.8 1.2 0.043 13.4 1.2 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain DUF5104 PF17117.5 EGF80756.1 - 0.033 14.6 0.2 0.069 13.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5104) DUF4558 PF15104.6 EGF80756.1 - 0.035 14.1 0.3 0.091 12.8 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) DUF4200 PF13863.6 EGF80756.1 - 0.058 13.8 0.4 0.058 13.8 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CM_2 PF01817.21 EGF80756.1 - 0.11 12.9 0.9 0.28 11.6 0.9 1.8 1 1 0 1 1 1 0 Chorismate mutase type II DHR10 PF18595.1 EGF80756.1 - 0.16 12.0 3.3 0.15 12.1 1.3 1.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF3232 PF11554.8 EGF80756.1 - 0.19 12.1 1.7 0.32 11.4 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3232) Jnk-SapK_ap_N PF09744.9 EGF80756.1 - 0.29 11.3 5.2 0.3 11.3 2.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 EGF80756.1 - 0.6 10.3 4.4 4.7 7.4 0.4 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 EGF80756.1 - 5.1 7.4 8.3 1.9 8.8 3.4 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain zf-HIT PF04438.16 EGF80757.1 - 6.8e-10 38.6 10.6 1.1e-09 38.0 10.6 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 EGF80757.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 EGF80757.1 - 0.036 14.2 12.3 0.058 13.5 12.3 1.4 1 0 0 1 1 1 0 MYND finger zf-C6H2 PF15801.5 EGF80757.1 - 0.068 13.5 8.6 0.18 12.2 8.6 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 EGF80757.1 - 0.26 9.1 3.2 0.26 9.1 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-met PF12874.7 EGF80757.1 - 7.2 7.2 7.4 1.3 9.5 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RTC4 PF14474.6 EGF80758.1 - 6.7e-26 90.8 0.0 1.3e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain ATP-synt_S1 PF05827.12 EGF80758.1 - 0.063 13.1 0.6 0.15 11.8 0.6 1.6 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Rtt102p PF09510.10 EGF80758.1 - 1.1 9.4 10.4 0.033 14.4 1.8 2.6 3 0 0 3 3 3 0 Rtt102p-like transcription regulator protein PI3_PI4_kinase PF00454.27 EGF80759.1 - 9.7e-42 143.5 0.0 2.1e-41 142.4 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WLM PF08325.10 EGF80760.1 - 2.5e-41 141.8 0.2 3.4e-41 141.4 0.2 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EGF80760.1 - 0.023 14.7 0.9 0.051 13.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Reprolysin_5 PF13688.6 EGF80760.1 - 0.036 14.2 0.5 0.051 13.7 0.5 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 WD40 PF00400.32 EGF80761.1 - 3.6e-25 87.7 18.9 2.4e-08 34.5 0.1 5.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EGF80761.1 - 2.5e-07 29.8 1.5 0.0061 15.3 0.1 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 TRAF_BIRC3_bd PF16673.5 EGF80763.1 - 0.69 9.7 4.7 3.1 7.7 0.3 2.7 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF573 PF04504.14 EGF80763.1 - 0.8 10.4 10.8 0.28 11.9 3.7 2.7 1 1 2 3 3 3 0 Protein of unknown function, DUF573 Calici_MSP PF05752.11 EGF80763.1 - 1.5 8.6 9.6 2.6 7.9 1.8 2.5 1 1 1 2 2 2 0 Calicivirus minor structural protein Noelin-1 PF12308.8 EGF80763.1 - 3.2 7.8 8.4 1.6 8.8 5.2 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF1319 PF07028.11 EGF80763.1 - 3.3 8.0 10.2 4.5 7.5 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Syntaxin-6_N PF09177.11 EGF80763.1 - 6.6 7.4 9.8 1.6 9.3 5.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nre_C PF04895.12 EGF80763.1 - 7.9 6.4 7.3 12 5.9 0.2 2.9 1 1 3 4 4 4 0 Archaeal Nre, C-terminal Bcr-Abl_Oligo PF09036.10 EGF80763.1 - 8 6.6 8.0 5.1 7.2 0.9 2.7 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Swi3 PF07962.12 EGF80764.1 - 9.2e-26 89.6 1.9 1.7e-25 88.8 1.9 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DUF2012 PF09430.10 EGF80765.1 - 5.3e-21 75.0 0.0 7.9e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) UPF0242 PF06785.11 EGF80765.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_M14 PF00246.24 EGF80766.1 - 8.5e-72 242.4 0.0 9.9e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ECH_1 PF00378.20 EGF80767.1 - 9.9e-35 120.0 0.1 7e-31 107.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF80767.1 - 3e-16 59.9 0.2 4.7e-14 52.6 0.1 2.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase MORN PF02493.20 EGF80768.1 - 2.6e-42 140.2 69.4 6e-07 29.0 2.1 11.4 11 1 0 11 11 11 10 MORN repeat TRAPPC10 PF12584.8 EGF80770.1 - 7.2e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 SeleniumBinding PF11524.8 EGF80770.1 - 0.087 13.3 0.1 0.66 10.5 0.1 2.3 2 0 0 2 2 2 0 Selenium binding protein GST_C_3 PF14497.6 EGF80771.1 - 7.4e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGF80771.1 - 0.0003 21.1 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF80771.1 - 0.0078 16.4 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BMC PF00936.19 EGF80771.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 BMC domain GST_C_2 PF13410.6 EGF80771.1 - 0.17 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tti2 PF10521.9 EGF80773.1 - 1.1e-20 74.4 0.7 2.2e-20 73.4 0.7 1.5 1 0 0 1 1 1 1 Tti2 family Vac14_Fab1_bd PF12755.7 EGF80773.1 - 0.085 13.5 0.3 4.1 8.1 0.0 3.6 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region TLD PF07534.16 EGF80774.1 - 1.3e-33 116.1 0.4 2.1e-33 115.5 0.4 1.3 1 0 0 1 1 1 1 TLD SRP14 PF02290.15 EGF80775.1 - 3.9e-25 88.0 1.0 3.9e-25 88.0 1.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF4404 PF14357.6 EGF80776.1 - 0.091 13.4 0.0 0.35 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) zf-C2HE PF16278.5 EGF80776.1 - 0.097 13.1 0.8 1.7 9.2 0.6 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger OTT_1508_deam PF14441.6 EGF80777.1 - 2.8e-11 43.3 1.9 6.3e-11 42.1 1.9 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Rep_trans PF02486.19 EGF80777.1 - 0.046 13.5 0.1 0.14 11.9 0.0 1.9 2 1 0 2 2 2 0 Replication initiation factor Prefoldin_2 PF01920.20 EGF80778.1 - 8.8e-22 77.1 12.4 1.2e-21 76.7 12.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EGF80778.1 - 0.0036 17.3 3.7 0.0059 16.6 3.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 EGF80778.1 - 0.041 14.1 5.2 0.057 13.6 5.2 1.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Syntaxin_2 PF14523.6 EGF80778.1 - 0.05 14.0 10.0 0.21 12.0 3.8 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Stealth_CR2 PF11380.8 EGF80778.1 - 0.067 13.4 0.2 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Stealth protein CR2, conserved region 2 Surp PF01805.20 EGF80778.1 - 0.081 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Surp module DUF5067 PF16729.5 EGF80778.1 - 0.082 12.8 4.0 0.14 12.1 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5067) Rx_N PF18052.1 EGF80778.1 - 0.14 12.5 4.5 0.31 11.4 0.4 2.4 1 1 1 2 2 2 0 Rx N-terminal domain Bcr-Abl_Oligo PF09036.10 EGF80778.1 - 0.48 10.5 4.3 0.15 12.1 0.5 2.0 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain YabA PF06156.13 EGF80778.1 - 0.67 10.6 9.7 3.5 8.3 1.7 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 EGF80778.1 - 1 9.2 13.3 1.8 8.4 1.6 2.5 2 1 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 EGF80778.1 - 1.7 9.1 8.7 0.63 10.6 1.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.6 EGF80778.1 - 2.8 8.4 11.8 3.2 8.2 11.8 1.1 1 0 0 1 1 1 0 AAA domain Spc24 PF08286.11 EGF80778.1 - 4 7.7 10.0 10 6.4 1.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_1 PF00515.28 EGF80779.1 - 3.3e-58 191.3 31.5 2.7e-08 33.3 0.0 10.8 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80779.1 - 5.2e-48 157.3 24.9 3.6e-06 26.7 0.1 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80779.1 - 6.8e-37 122.6 26.8 8.2e-08 31.9 0.1 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 EGF80779.1 - 1.3e-29 102.5 2.7 3.7e-05 24.3 0.1 6.4 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 EGF80779.1 - 3.1e-27 92.9 14.6 0.0007 19.8 0.1 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGF80779.1 - 3.2e-26 89.8 14.2 0.0018 18.9 0.0 9.1 3 3 5 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EGF80779.1 - 1e-22 79.5 30.0 2.9e-06 26.9 1.0 9.8 5 2 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 EGF80779.1 - 2.5e-22 79.2 13.6 1.3e-05 25.6 0.2 6.5 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80779.1 - 2.4e-20 72.6 26.5 3.8e-05 23.9 2.5 8.2 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGF80779.1 - 9.3e-20 69.2 18.5 0.044 13.8 0.3 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGF80779.1 - 4.9e-19 67.6 22.2 0.0009 19.7 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGF80779.1 - 6.7e-17 61.4 8.8 0.0031 17.6 0.4 6.6 2 2 5 7 7 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF80779.1 - 1.2e-09 38.3 22.3 1.4e-05 25.2 3.0 4.0 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGF80779.1 - 5e-08 32.5 10.8 0.026 13.7 0.4 5.0 1 1 3 4 4 4 3 Tetratricopeptide repeat DUF2225 PF09986.9 EGF80779.1 - 1.2e-06 28.4 4.0 0.065 13.0 0.2 4.0 2 2 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 EGF80779.1 - 8.5e-05 21.7 1.6 0.021 13.8 0.1 3.0 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 EGF80779.1 - 9.7e-05 22.8 5.4 2.2 8.7 0.3 3.5 3 0 0 3 3 3 3 Bacterial transcriptional activator domain TPR_20 PF14561.6 EGF80779.1 - 0.00097 19.4 0.7 0.031 14.6 0.1 3.4 4 1 2 6 6 4 1 Tetratricopeptide repeat DUF4919 PF16266.5 EGF80779.1 - 0.0012 18.9 0.1 0.13 12.2 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4919) TPR_21 PF09976.9 EGF80779.1 - 0.0013 18.5 6.3 4.5 6.9 0.9 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain SNAP PF14938.6 EGF80779.1 - 0.023 14.1 13.9 0.42 10.0 1.8 4.7 2 2 1 4 4 4 0 Soluble NSF attachment protein, SNAP Paf67 PF10255.9 EGF80779.1 - 0.036 13.0 0.5 0.18 10.7 0.4 1.9 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_MalT PF17874.1 EGF80779.1 - 0.054 12.9 0.1 5.8 6.2 0.0 2.7 2 1 0 2 2 2 0 MalT-like TPR region TipAS PF07739.13 EGF80779.1 - 0.46 11.1 3.7 3.6 8.2 0.5 3.2 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain tRNA-synt_2d PF01409.20 EGF80780.1 - 1.5e-48 165.4 0.2 6.2e-27 94.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGF80780.1 - 6.6e-24 84.2 0.1 1.7e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain PRP38 PF03371.15 EGF80782.1 - 3.4e-58 196.4 0.1 3.9e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 PRP38 family VPS13 PF16908.5 EGF80783.1 - 2e-70 237.3 1.0 5.5e-69 232.6 0.4 2.9 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 EGF80783.1 - 2.3e-69 233.8 0.5 2.2e-65 220.7 0.1 3.5 2 1 1 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 EGF80783.1 - 7.3e-67 224.6 5.2 4.8e-62 208.9 0.2 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 EGF80783.1 - 3.8e-60 203.3 11.3 5.3e-57 193.0 0.8 5.2 4 2 1 5 5 5 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 EGF80783.1 - 5.1e-23 81.4 0.2 1.6e-22 79.8 0.2 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGF80783.1 - 8e-11 42.1 0.2 1.4e-07 31.7 0.0 3.5 3 0 0 3 3 3 2 Autophagy-related protein C terminal domain DUF4320 PF14208.6 EGF80783.1 - 0.078 13.1 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) ANAPC4 PF12896.7 EGF80784.1 - 6.3e-12 45.4 1.7 6.3e-12 45.4 1.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGF80784.1 - 0.00021 21.5 0.2 0.00063 20.0 0.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Glu_dehyd_C PF16912.5 EGF80784.1 - 0.086 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus RNA_pol_Rpb5_C PF01191.19 EGF80785.1 - 1.7e-33 114.3 0.2 4.4e-33 113.0 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGF80785.1 - 1.4e-28 99.3 0.0 2.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Oscp1 PF10188.9 EGF80785.1 - 0.072 13.2 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Organic solute transport protein 1 Mrr_cat PF04471.12 EGF80785.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease Kinesin PF00225.23 EGF80786.1 - 2.3e-117 391.6 0.0 2.3e-117 391.6 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGF80786.1 - 2.2e-25 89.4 0.1 6e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 EGF80786.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain DUF3037 PF11236.8 EGF80786.1 - 0.33 11.4 3.3 1.8 9.0 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) AAA_22 PF13401.6 EGF80786.1 - 0.66 10.2 11.7 0.3 11.3 0.2 3.1 3 1 0 3 3 3 0 AAA domain Kinesin_assoc PF16183.5 EGF80786.1 - 2 8.5 14.1 14 5.8 14.1 2.4 1 1 0 1 1 1 0 Kinesin-associated ATP12 PF07542.11 EGF80788.1 - 6.7e-31 107.0 0.0 1.1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein ParA PF10609.9 EGF80789.1 - 6e-99 330.5 0.5 7.1e-99 330.2 0.5 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGF80789.1 - 9.5e-11 41.9 0.0 1.1e-09 38.4 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGF80789.1 - 1.5e-07 31.5 0.1 8.7e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EGF80789.1 - 5.6e-06 25.8 0.7 0.00076 18.8 0.2 2.4 1 1 1 2 2 2 2 Anion-transporting ATPase MipZ PF09140.11 EGF80789.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 EGF80789.1 - 0.0009 19.1 0.0 0.038 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EGF80789.1 - 0.0067 15.9 0.0 0.13 11.7 0.0 2.5 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 EGF80789.1 - 0.016 15.1 0.0 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EGF80789.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF80789.1 - 0.03 14.7 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PcrB PF01884.17 EGF80789.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PcrB family CBP_BcsQ PF06564.12 EGF80789.1 - 0.11 11.9 0.0 0.48 9.9 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 EGF80789.1 - 0.12 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EGF80789.1 - 0.15 11.9 0.1 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain INCENP_ARK-bind PF03941.15 EGF80790.1 - 5.5e-17 61.4 0.1 2e-16 59.6 0.1 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region CDO_I PF05995.12 EGF80791.1 - 1.1e-50 171.2 0.0 1.6e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EGF80791.1 - 3e-07 30.1 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO Fmp27_GFWDK PF10347.9 EGF80792.1 - 0.025 14.7 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UPF0061 PF02696.14 EGF80793.1 - 4.8e-126 421.3 0.1 5.7e-126 421.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RBB1NT PF08169.11 EGF80793.1 - 0.069 13.3 0.1 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 RBB1NT (NUC162) domain Tetraspanin PF00335.20 EGF80794.1 - 1.2e-32 113.5 9.7 1.4e-32 113.3 9.7 1.1 1 0 0 1 1 1 1 Tetraspanin family FHA PF00498.26 EGF80795.1 - 8.9e-08 32.4 0.0 2.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain E1-E2_ATPase PF00122.20 EGF80796.1 - 1.2e-42 145.5 5.0 1.2e-42 145.5 5.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGF80796.1 - 4.3e-38 131.7 0.1 8.1e-38 130.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGF80796.1 - 1.5e-29 102.2 3.2 1.8e-13 50.7 0.2 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGF80796.1 - 0.0021 17.9 1.7 0.018 14.8 1.2 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PaaX PF07848.12 EGF80796.1 - 0.028 14.6 0.1 7.2 6.9 0.0 3.5 3 0 0 3 3 3 0 PaaX-like protein HAD PF12710.7 EGF80796.1 - 0.032 14.6 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GerE PF00196.19 EGF80796.1 - 0.061 12.9 0.0 2.5 7.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DREV PF05219.12 EGF80796.1 - 0.083 12.0 0.0 0.29 10.2 0.0 1.8 1 1 0 1 1 1 0 DREV methyltransferase Ribonuclease_3 PF00636.26 EGF80797.1 - 1.7e-37 128.2 0.0 2e-17 63.7 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF80797.1 - 3.6e-23 82.1 0.0 1.3e-11 44.8 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EGF80797.1 - 4.4e-13 49.2 0.2 1.8e-12 47.2 0.2 2.1 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.22 EGF80797.1 - 1.3e-05 25.0 0.9 1.3e-05 25.0 0.9 2.7 3 0 0 3 3 3 1 PAZ domain Helicase_C PF00271.31 EGF80797.1 - 2.6e-05 24.5 0.0 8.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGF80797.1 - 4.7e-05 23.2 0.1 0.00013 21.8 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF80797.1 - 0.0053 16.8 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GluR_Homer-bdg PF10606.9 EGF80797.1 - 0.025 14.8 1.5 0.091 13.0 1.5 2.0 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor dsrm PF00035.26 EGF80797.1 - 0.068 13.9 1.6 0.23 12.2 0.2 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif AAA_16 PF13191.6 EGF80798.1 - 3.8e-05 24.1 0.0 9.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Surp PF01805.20 EGF80798.1 - 0.025 14.6 0.0 2.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Surp module PDE4_UCR PF18100.1 EGF80798.1 - 0.08 13.6 2.2 0.38 11.4 0.1 2.4 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) TraK PF06586.11 EGF80798.1 - 0.18 11.5 0.0 0.82 9.3 0.0 1.9 2 0 0 2 2 2 0 TraK protein Phosphoesterase PF04185.14 EGF80799.1 - 3e-76 256.9 1.0 3.8e-76 256.6 1.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Nic96 PF04097.14 EGF80799.1 - 0.21 10.0 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 MucBP_2 PF17965.1 EGF80800.1 - 0.014 16.0 0.0 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Mucin binding domain Ribosomal_S13_N PF08069.12 EGF80800.1 - 0.072 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Polysacc_deac_1 PF01522.21 EGF80801.1 - 1.6e-18 66.8 0.0 2.6e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 EGF80802.1 - 2.9e-22 78.9 0.0 5.8e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGF80802.1 - 4.5e-16 59.0 55.6 4.3e-06 27.1 13.2 3.5 3 0 0 3 3 3 3 Chitin recognition protein ADK PF00406.22 EGF80803.1 - 1.2e-44 152.0 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGF80803.1 - 5.9e-19 68.8 0.0 8.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGF80803.1 - 3e-12 46.3 0.0 8e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGF80803.1 - 0.00012 22.6 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGF80803.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF80803.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGF80803.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase TPR_1 PF00515.28 EGF80804.1 - 3.7e-11 42.3 1.5 0.00064 19.4 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80804.1 - 1.1e-10 40.8 1.1 0.00045 20.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF80804.1 - 1.2e-06 28.0 0.1 0.00052 19.6 0.0 2.7 2 1 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 EGF80804.1 - 1.8e-06 28.3 0.6 0.12 13.3 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF80804.1 - 2.8e-06 27.9 1.1 0.028 15.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF80804.1 - 1.1e-05 25.7 0.9 0.034 14.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80804.1 - 4.1e-05 23.4 1.1 0.042 14.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF80804.1 - 0.00048 20.0 2.6 0.086 12.9 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF80804.1 - 0.006 17.1 0.0 1.6 9.3 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF80804.1 - 0.063 13.5 2.3 5.7 7.2 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Se-cys_synth_N PF12390.8 EGF80804.1 - 0.077 13.2 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Selenocysteine synthase N terminal TPR_9 PF13371.6 EGF80804.1 - 0.09 12.9 0.9 1.5 9.0 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EGF80805.1 - 9.6e-38 130.0 7.6 1.4e-36 126.2 7.6 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF2070 PF09843.9 EGF80805.1 - 0.1 10.9 0.1 0.44 8.8 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) GATase_4 PF13230.6 EGF80805.1 - 0.12 11.3 0.4 8.5 5.2 0.0 2.3 1 1 0 2 2 2 0 Glutamine amidotransferases class-II SNO PF01174.19 EGF80807.1 - 3.1e-53 180.4 0.0 4.1e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGF80807.1 - 7e-12 45.4 0.0 8.6e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EGF80807.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EGF80807.1 - 0.0002 21.2 0.0 0.0005 19.9 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family GATase PF00117.28 EGF80807.1 - 0.00052 19.8 0.3 0.0042 16.9 0.3 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGF80807.1 - 0.011 15.5 0.1 0.052 13.3 0.1 2.1 1 1 0 1 1 1 0 Peptidase C26 BPL_N PF09825.9 EGF80807.1 - 0.032 13.3 0.0 1.7 7.7 0.0 2.0 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal MaoC_dehydratas PF01575.19 EGF80808.1 - 0.00099 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain zf-C2H2 PF00096.26 EGF80809.1 - 4.6e-12 45.7 10.5 6.9e-08 32.5 0.8 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF80809.1 - 6.6e-12 45.2 10.6 1.7e-05 25.2 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF80809.1 - 1.1e-09 38.3 11.7 3.3e-07 30.4 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGF80809.1 - 2.7e-07 30.4 9.1 6.7e-06 26.0 0.4 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EGF80809.1 - 2.6e-06 27.6 5.1 0.00014 22.1 0.4 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGF80809.1 - 3.8e-06 27.0 6.8 0.00066 19.9 0.5 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 EGF80809.1 - 0.0015 18.8 1.2 0.15 12.3 0.0 2.9 3 0 0 3 3 3 1 zinc-ribbon zf-Di19 PF05605.12 EGF80809.1 - 0.0023 18.2 8.1 1.2 9.5 0.6 2.7 1 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 EGF80809.1 - 0.0028 17.5 1.6 0.61 10.0 0.3 2.2 2 0 0 2 2 2 1 PHD-finger Zn-ribbon_8 PF09723.10 EGF80809.1 - 0.0046 17.0 2.1 0.025 14.7 2.1 2.1 1 1 0 1 1 1 1 Zinc ribbon domain DUF3268 PF11672.8 EGF80809.1 - 0.0079 16.5 0.2 0.0079 16.5 0.2 1.4 2 0 0 2 2 1 1 zinc-finger-containing domain zf_UBZ PF18439.1 EGF80809.1 - 0.021 14.4 3.7 5.1 6.8 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 EGF80809.1 - 0.024 15.3 5.3 0.048 14.3 2.6 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 EGF80809.1 - 0.028 14.7 5.1 0.13 12.7 0.0 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HypA PF01155.19 EGF80809.1 - 0.034 14.2 0.2 0.034 14.2 0.2 1.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_5 PF13909.6 EGF80809.1 - 0.034 13.9 6.2 2.2 8.1 2.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain FYVE PF01363.21 EGF80809.1 - 0.055 13.6 4.2 0.65 10.2 4.2 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HE PF16278.5 EGF80809.1 - 0.06 13.8 1.1 0.06 13.8 1.1 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 EGF80809.1 - 0.073 13.1 11.0 0.036 14.1 1.5 3.0 1 1 2 3 3 3 0 BED zinc finger zf-Sec23_Sec24 PF04810.15 EGF80809.1 - 0.11 12.6 4.8 0.94 9.6 0.1 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger TFIIS_C PF01096.18 EGF80809.1 - 0.11 12.4 2.8 0.42 10.5 0.6 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-AN1 PF01428.16 EGF80809.1 - 0.16 12.1 8.3 6.3 7.1 0.6 3.1 3 0 0 3 3 3 0 AN1-like Zinc finger zf_ZIC PF18366.1 EGF80809.1 - 0.22 11.7 5.0 1.6 8.9 0.1 2.7 3 0 0 3 3 3 0 Zic proteins zinc finger domain Actin_micro PF17003.5 EGF80809.1 - 0.29 10.3 1.7 0.81 8.8 1.1 1.8 1 1 0 1 1 1 0 Putative actin-like family C1_2 PF03107.16 EGF80809.1 - 0.31 11.4 9.0 9.8 6.6 9.0 2.9 1 1 0 1 1 1 0 C1 domain DUF2256 PF10013.9 EGF80809.1 - 0.33 11.1 3.2 2.8 8.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-SNAP50_C PF12251.8 EGF80809.1 - 0.33 10.6 5.5 0.46 10.1 5.5 1.3 1 1 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal GFA PF04828.14 EGF80809.1 - 0.33 11.3 3.9 2.5 8.5 0.0 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ADK_lid PF05191.14 EGF80809.1 - 0.47 10.5 4.9 1.2 9.2 1.5 2.3 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-HIT PF04438.16 EGF80809.1 - 1.3 8.9 10.6 8.7 6.3 0.5 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-trcl PF13451.6 EGF80809.1 - 1.3 8.9 5.1 18 5.3 0.1 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF2197 PF09963.9 EGF80809.1 - 2.3 8.6 7.6 0.76 10.1 1.8 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_11 PF16622.5 EGF80809.1 - 8.2 6.3 8.0 11 5.9 0.1 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Spem1 PF15670.5 EGF80811.1 - 3.7 7.1 7.6 0.29 10.7 1.5 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 SesA PF17107.5 EGF80812.1 - 0.096 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases V-SNARE_C PF12352.8 EGF80812.1 - 0.12 12.7 1.5 11 6.4 0.0 3.0 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF2802 PF10975.8 EGF80813.1 - 0.0081 16.3 0.0 3.4 7.9 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2802) DUF5333 PF17267.2 EGF80815.1 - 0.013 15.6 1.3 2.7 8.2 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5333) STI1 PF17830.1 EGF80815.1 - 0.1 12.6 2.1 17 5.5 0.2 3.2 3 1 0 3 3 3 0 STI1 domain FAM183 PF14886.6 EGF80816.1 - 1.1e-05 26.1 0.5 2.9e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 FAM183A and FAM183B related LLC1 PF14945.6 EGF80816.1 - 0.022 15.3 1.2 0.044 14.4 0.1 2.1 3 0 0 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein BCL_N PF04714.13 EGF80816.1 - 0.1 12.7 2.3 14 5.8 1.1 2.5 2 0 0 2 2 2 0 BCL7, N-terminal conserver region CobU PF02283.16 EGF80816.1 - 0.17 11.4 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pkinase PF00069.25 EGF80818.1 - 1.4e-44 152.4 0.1 8.9e-41 140.0 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80818.1 - 3.7e-12 46.1 0.0 1.2e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF80818.1 - 6.7e-08 32.1 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF80818.1 - 3.8e-06 26.6 6.3 8.5e-06 25.5 0.1 3.2 3 0 0 3 3 3 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGF80818.1 - 0.00078 19.1 0.1 0.002 17.7 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGF80818.1 - 0.0022 18.0 0.1 0.021 14.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sel1 PF08238.12 EGF80820.1 - 1.8e-11 44.3 3.2 0.00055 20.5 0.0 5.2 5 0 0 5 5 5 3 Sel1 repeat SesA PF17107.5 EGF80821.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases V-ATPase_G_2 PF16999.5 EGF80824.1 - 0.0034 17.8 2.9 0.082 13.3 3.3 2.3 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit DUF4709 PF15821.5 EGF80824.1 - 0.055 13.8 5.5 0.08 13.2 2.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) zf-SAP30 PF13866.6 EGF80824.1 - 0.072 13.2 5.3 1.6 8.9 0.0 3.3 3 0 0 3 3 3 0 SAP30 zinc-finger Phage_Mu_Gam PF07352.12 EGF80824.1 - 0.19 11.7 4.9 0.55 10.1 1.0 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Nbl1_Borealin_N PF10444.9 EGF80824.1 - 0.31 10.7 5.9 0.28 10.9 2.8 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal D5_N PF08706.11 EGF80824.1 - 0.45 10.8 3.8 0.88 9.8 3.8 1.6 1 0 0 1 1 1 0 D5 N terminal like Asp PF00026.23 EGF80826.1 - 1.5e-12 47.6 0.0 3.1e-12 46.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80826.1 - 1.5e-06 28.0 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal IstB_IS21 PF01695.17 EGF80828.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF641 PF04859.12 EGF80829.1 - 0.066 13.6 0.3 0.12 12.8 0.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ABC_tran PF00005.27 EGF80831.1 - 1.9e-28 99.7 0.0 6.4e-28 98.0 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF80831.1 - 6.3e-14 52.5 0.6 2.8e-10 40.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF80831.1 - 0.00016 22.2 1.1 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGF80831.1 - 0.00026 20.8 0.3 0.14 11.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 EGF80831.1 - 0.0009 18.7 0.9 0.14 11.6 0.1 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGF80831.1 - 0.0025 17.7 0.1 0.006 16.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF80831.1 - 0.0036 17.0 0.1 0.0077 16.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGF80831.1 - 0.0073 16.7 0.1 0.14 12.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RRM_Rrp7 PF17799.1 EGF80831.1 - 0.026 14.3 0.4 0.19 11.5 0.1 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain AAA_13 PF13166.6 EGF80831.1 - 0.045 12.4 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DED PF01335.21 EGF80831.1 - 0.056 13.8 0.7 0.19 12.1 0.4 2.0 2 0 0 2 2 2 0 Death effector domain DCX PF03607.17 EGF80831.1 - 0.058 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Doublecortin DLIC PF05783.11 EGF80831.1 - 0.071 11.9 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 EGF80831.1 - 0.1 12.6 0.1 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Asp PF00026.23 EGF80832.1 - 5.7e-10 39.1 0.0 1.3e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80832.1 - 0.0018 18.1 0.0 0.0067 16.2 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal WDCP PF15390.6 EGF80834.1 - 0.55 8.5 6.6 0.85 7.9 6.6 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Hid1 PF12722.7 EGF80834.1 - 2.6 6.1 7.6 3.3 5.7 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec2p PF06428.11 EGF80836.1 - 0.12 12.4 2.4 5.9 6.9 0.1 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF80836.1 - 0.18 12.0 4.2 6.9 6.8 4.2 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2511 PF10709.9 EGF80839.1 - 0.0026 18.0 4.7 3.1 8.1 0.0 4.5 2 2 3 5 5 5 2 Protein of unknown function (DUF2511) MINDY_DUB PF04424.13 EGF80839.1 - 0.0037 17.3 0.1 9.5 6.3 0.0 3.3 2 1 1 3 3 3 1 MINDY deubiquitinase NQR2_RnfD_RnfE PF03116.15 EGF80839.1 - 0.005 16.3 12.9 7 6.0 3.2 4.2 4 0 0 4 4 4 3 NQR2, RnfD, RnfE family Cys_rich_FGFR PF00839.17 EGF80839.1 - 0.059 13.5 18.7 18 5.6 0.2 5.4 5 0 0 5 5 5 0 Cysteine rich repeat GSHPx PF00255.19 EGF80839.1 - 0.36 10.4 8.5 15 5.2 0.0 4.2 4 1 1 5 5 5 0 Glutathione peroxidase T_cell_tran_alt PF15128.6 EGF80840.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Asp PF00026.23 EGF80841.1 - 0.0014 18.2 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease T_cell_tran_alt PF15128.6 EGF80844.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Sec2p PF06428.11 EGF80845.1 - 0.16 12.0 3.1 7.3 6.6 0.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF80845.1 - 0.81 9.9 5.0 18 5.5 5.0 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IstB_IS21 PF01695.17 EGF80846.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGF80846.1 - 0.1 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain LupA PF18242.1 EGF80847.1 - 0.066 12.9 0.1 1.3 8.6 0.0 2.2 1 1 1 2 2 2 0 Legionella ubiquitin-specific protease A domain Asp PF00026.23 EGF80848.1 - 2.7e-13 50.0 0.1 4.4e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80848.1 - 4.9e-08 32.9 0.2 5e-07 29.6 0.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Xlink PF00193.17 EGF80848.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Extracellular link domain DUF1505 PF07403.11 EGF80849.1 - 0.024 14.8 2.4 0.024 14.8 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) DUF4692 PF15763.5 EGF80849.1 - 2.1 8.8 14.0 0.18 12.2 5.9 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) 5_nucleotid_C PF02872.18 EGF80850.1 - 6.6e-32 110.9 0.0 1.3e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGF80850.1 - 3e-12 47.5 0.2 4.5e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5578 PF17741.1 EGF80851.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5578) DUF4149 PF13664.6 EGF80851.1 - 0.11 12.8 2.2 0.17 12.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) UPF0014 PF03649.13 EGF80852.1 - 3.4e-73 246.0 21.0 4.1e-73 245.7 21.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) PIRT PF15099.6 EGF80852.1 - 0.17 11.4 3.7 0.83 9.2 0.1 2.9 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family ATPase_gene1 PF09527.10 EGF80852.1 - 8.7 6.6 9.8 1.6 9.0 1.2 3.2 2 2 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter MMS1_N PF10433.9 EGF80853.1 - 2.4e-156 521.2 0.0 3.2e-156 520.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGF80853.1 - 2.3e-95 319.6 0.0 3.4e-94 315.8 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MIP PF00230.20 EGF80854.1 - 1.7e-42 145.7 20.3 2.7e-25 89.4 9.2 2.1 2 0 0 2 2 2 2 Major intrinsic protein DUF3488 PF11992.8 EGF80854.1 - 0.086 11.8 2.1 0.11 11.4 0.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3488) COPIIcoated_ERV PF07970.12 EGF80855.1 - 1.4e-83 280.1 0.6 2.2e-83 279.5 0.6 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGF80855.1 - 1.3e-29 102.3 0.5 2.8e-29 101.3 0.1 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_S26 PF10502.9 EGF80856.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 ANAPC4_WD40 PF12894.7 EGF80857.1 - 7.4e-10 39.0 5.8 4.9e-05 23.6 0.0 6.2 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGF80857.1 - 1.5e-08 34.1 4.1 0.0026 16.9 0.1 4.8 4 1 1 5 5 5 2 Coatomer WD associated region eIF2A PF08662.11 EGF80857.1 - 0.0005 20.0 5.7 0.00073 19.5 0.4 3.3 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 EGF80857.1 - 0.00066 19.6 1.0 0.00066 19.6 1.0 3.8 2 1 2 4 4 4 1 Region in Clathrin and VPS zf-ribbon_3 PF13248.6 EGF80857.1 - 0.045 13.2 3.1 0.15 11.5 3.1 2.0 1 0 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.32 EGF80857.1 - 0.059 14.3 14.7 52 4.9 0.1 8.0 6 1 1 7 7 6 0 WD domain, G-beta repeat TPR_12 PF13424.6 EGF80857.1 - 0.15 12.3 4.1 11 6.4 0.1 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 EGF80857.1 - 0.16 11.7 3.0 0.52 10.1 3.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain NMDAR2_C PF10565.9 EGF80857.1 - 0.18 10.7 0.3 0.27 10.1 0.3 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus TPR_7 PF13176.6 EGF80857.1 - 0.52 10.5 2.9 2 8.6 0.6 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Chlam_OMP3 PF03503.13 EGF80857.1 - 0.8 10.1 5.0 1.2 9.5 2.3 2.5 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 tRNA_NucTran2_2 PF13735.6 EGF80857.1 - 2.1 8.3 4.9 5.9 6.9 2.4 3.1 3 1 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative TPR_1 PF00515.28 EGF80857.1 - 2.8 7.9 17.5 0.29 11.0 0.9 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_15 PF17032.5 EGF80857.1 - 8.5 7.2 10.8 0.53 11.1 0.5 3.5 4 0 0 4 4 2 0 zinc-ribbon family ThiF PF00899.21 EGF80859.1 - 2.6e-66 223.5 0.1 3.5e-66 223.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGF80859.1 - 1.2e-25 89.5 1.0 1.9e-25 88.8 1.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EGF80859.1 - 0.00067 19.7 0.3 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGF80859.1 - 0.045 14.3 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EGF80859.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EGF80859.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ecm33 PF12454.8 EGF80859.1 - 0.13 12.4 1.1 0.31 11.2 1.1 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein PRP1_N PF06424.12 EGF80860.1 - 3.4e-50 170.3 5.3 8e-50 169.1 5.3 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGF80860.1 - 1.2e-27 94.2 30.5 0.0054 17.4 0.0 13.6 5 3 10 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 EGF80860.1 - 9.1e-22 77.4 19.5 3.1e-07 30.8 0.1 9.9 8 3 2 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80860.1 - 1.8e-11 43.3 2.7 0.092 13.0 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF80860.1 - 3.6e-09 36.0 12.5 0.19 11.9 0.0 9.0 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF80860.1 - 5.1e-07 29.6 0.2 3.4 8.3 0.1 8.6 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF80860.1 - 6.5e-07 29.9 19.8 0.015 15.9 0.6 7.2 6 2 4 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGF80860.1 - 1.4e-06 27.9 0.9 1.3 9.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF80860.1 - 1.6e-05 24.4 1.2 5.2 6.9 0.0 6.0 6 1 0 6 6 6 1 TPR repeat TPR_12 PF13424.6 EGF80860.1 - 1.7e-05 25.0 5.9 1.5 9.1 0.1 7.2 7 2 0 7 7 6 1 Tetratricopeptide repeat Suf PF05843.14 EGF80860.1 - 0.00033 20.8 0.8 0.061 13.3 0.0 3.8 5 0 0 5 5 4 1 Suppressor of forked protein (Suf) FAT PF02259.23 EGF80860.1 - 0.0022 17.3 7.0 0.72 9.0 5.3 3.9 2 1 0 2 2 2 1 FAT domain TPR_21 PF09976.9 EGF80860.1 - 0.003 17.3 8.6 0.14 11.9 0.2 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 EGF80860.1 - 0.0035 16.8 0.2 5.5 6.3 0.0 3.9 4 0 0 4 4 4 1 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 EGF80860.1 - 0.01 16.0 0.1 4.1 7.7 0.1 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 EGF80860.1 - 0.013 14.3 1.0 4.7 5.8 0.1 4.1 3 1 1 5 5 5 0 Protein of unknown function (DUF3808) NARP1 PF12569.8 EGF80860.1 - 0.05 12.5 7.7 2.1 7.1 0.1 4.5 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EGF80860.1 - 0.32 11.2 10.2 0.79 9.9 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF80860.1 - 0.37 11.5 17.4 10 7.0 0.0 9.4 11 1 0 11 11 10 0 Tetratricopeptide repeat Velvet PF11754.8 EGF80861.1 - 7.9e-49 166.8 1.1 7.9e-49 166.8 1.1 2.7 2 1 0 2 2 2 1 Velvet factor MDM10 PF12519.8 EGF80862.1 - 3.6e-34 118.4 0.8 2.5e-14 53.0 0.0 3.1 1 1 2 3 3 3 3 Mitochondrial distribution and morphology protein 10 DUF3947 PF13135.6 EGF80863.1 - 0.0061 16.7 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3947) Sas10 PF09368.10 EGF80864.1 - 1.2e-25 89.7 6.0 3.2e-25 88.4 6.0 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGF80864.1 - 0.024 15.2 0.8 0.14 12.8 0.2 2.7 2 0 0 2 2 2 0 Sas10/Utp3/C1D family HMA PF00403.26 EGF80865.1 - 5.9e-50 167.6 4.3 6.7e-13 48.9 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 EGF80865.1 - 2.2e-46 157.6 1.8 2.2e-46 157.6 1.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGF80865.1 - 8.4e-43 147.1 0.1 1.4e-42 146.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGF80865.1 - 0.093 12.4 1.1 0.24 11.1 0.3 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fer2_BFD PF04324.15 EGF80865.1 - 0.41 11.0 12.2 9 6.7 0.1 4.9 5 0 0 5 5 5 0 BFD-like [2Fe-2S] binding domain DEAD_2 PF06733.15 EGF80866.1 - 3.7e-54 183.0 0.1 7.3e-54 182.0 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 EGF80866.1 - 8.8e-43 146.4 0.0 1.7e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EGF80866.1 - 2.1e-39 135.2 2.5 1.4e-34 119.5 0.4 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EGF80866.1 - 2.7e-05 24.3 0.0 0.00026 21.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGF80866.1 - 0.0001 21.2 0.0 0.00028 19.7 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 EGF80866.1 - 0.0081 15.9 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase YtxC PF08812.11 EGF80866.1 - 0.15 11.6 0.2 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 YtxC-like family SURF4 PF02077.15 EGF80867.1 - 9.8e-87 290.9 10.2 1.1e-86 290.7 10.2 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 EGF80867.1 - 0.028 14.6 1.2 0.028 14.6 1.2 3.0 2 2 2 4 4 4 0 HR-like lesion-inducing Asp PF00026.23 EGF80870.1 - 2.8e-15 56.6 0.1 7e-15 55.2 0.1 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF80870.1 - 9.2e-06 25.5 0.0 9.7e-05 22.2 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF80870.1 - 0.00094 19.8 0.1 0.27 11.9 0.0 3.3 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 EGF80870.1 - 0.021 15.4 0.1 4.1 8.0 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease DUF742 PF05331.11 EGF80870.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TetM_leader PF08076.11 EGF80871.1 - 0.039 13.7 19.6 1.5e+02 2.3 0.1 8.9 8 0 0 8 8 8 0 Tetracycline resistance determinant leader peptide AAA PF00004.29 EGF80872.1 - 3.2e-07 30.8 0.0 5.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF80872.1 - 0.00045 19.8 0.0 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGF80872.1 - 0.0012 19.4 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain PRTase_1 PF11202.8 EGF80872.1 - 0.002 17.4 0.0 0.0074 15.6 0.0 1.9 3 0 0 3 3 3 1 Phosphoribosyl transferase (PRTase) AAA_16 PF13191.6 EGF80872.1 - 0.003 18.0 0.0 0.014 15.8 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EGF80872.1 - 0.0074 16.0 0.1 0.025 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGF80872.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGF80872.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGF80872.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TK PF00265.18 EGF80872.1 - 0.034 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase AAA_11 PF13086.6 EGF80872.1 - 0.037 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF80872.1 - 0.045 14.1 0.1 0.15 12.5 0.1 2.0 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EGF80872.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGF80872.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGF80872.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain PRTase_1 PF11202.8 EGF80874.1 - 0.0027 17.0 0.0 0.0087 15.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase (PRTase) AAA PF00004.29 EGF80874.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T3SSipB PF16535.5 EGF80875.1 - 0.022 15.2 0.8 0.022 15.2 0.8 2.5 2 1 1 3 3 3 0 Type III cell invasion protein SipB Jnk-SapK_ap_N PF09744.9 EGF80875.1 - 0.63 10.2 17.4 0.67 10.2 3.5 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Sec20 PF03908.13 EGF80875.1 - 2 8.4 6.2 18 5.4 0.2 3.5 2 1 1 3 3 3 0 Sec20 MetOD2 PF18548.1 EGF80875.1 - 5 7.3 10.0 9.6 6.4 4.8 2.9 2 1 0 2 2 2 0 Metanogen output domain 2 CENP-Q PF13094.6 EGF80875.1 - 8.4 6.6 19.1 1.7 8.8 11.7 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cyclin_N PF00134.23 EGF80876.1 - 3.6e-25 88.1 0.0 7.9e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF80876.1 - 0.14 12.3 6.3 0.061 13.4 2.4 2.5 3 0 0 3 3 3 0 Cyclin, C-terminal domain ATP-synt_10 PF05176.14 EGF80877.1 - 4.3e-31 108.1 0.5 6.2e-31 107.6 0.5 1.2 1 0 0 1 1 1 1 ATP10 protein Rhomboid PF01694.22 EGF80878.1 - 5.4e-20 71.9 10.8 7.1e-20 71.5 10.8 1.2 1 0 0 1 1 1 1 Rhomboid family Auts2 PF15336.6 EGF80878.1 - 0.25 11.5 1.0 0.33 11.0 1.0 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein LepA_C PF06421.12 EGF80879.1 - 1.7e-45 153.6 2.2 3.2e-45 152.7 2.2 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 EGF80879.1 - 4.5e-45 153.6 0.0 1.2e-44 152.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGF80879.1 - 5.4e-20 71.2 0.0 1.5e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGF80879.1 - 3.1e-06 27.5 0.5 7.8e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF80879.1 - 2.3e-05 24.4 0.0 6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EGF80879.1 - 8.7e-05 22.5 0.0 0.00037 20.5 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II RF3_C PF16658.5 EGF80879.1 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EGF80879.1 - 0.03 13.8 0.0 0.097 12.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DNA_pol_A_exo1 PF01612.20 EGF80879.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease Aa_trans PF01490.18 EGF80880.1 - 0.0044 15.8 31.1 0.0068 15.1 31.1 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_holin_5_1 PF06946.11 EGF80880.1 - 0.016 15.5 1.2 0.19 12.1 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 PARG_cat PF05028.14 EGF80881.1 - 1.5e-103 346.7 0.0 2.1e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Herpes_HEPA PF03324.14 EGF80881.1 - 0.15 12.5 0.4 0.39 11.2 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein DUF2052 PF09747.9 EGF80882.1 - 1.6e-37 129.6 12.6 1.6e-37 129.6 12.6 1.4 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DUF1690 PF07956.11 EGF80883.1 - 1.3e-14 54.8 6.3 1e-10 42.2 2.0 2.4 1 1 1 2 2 2 2 Protein of Unknown function (DUF1690) Phage_F PF02305.17 EGF80883.1 - 0.008 15.0 0.0 0.0096 14.7 0.0 1.1 1 0 0 1 1 1 1 Capsid protein (F protein) FAM75 PF14650.6 EGF80883.1 - 0.03 13.9 0.6 0.03 13.9 0.6 1.4 2 0 0 2 2 2 0 FAM75 family efThoc1 PF11957.8 EGF80884.1 - 7.4e-87 292.1 8.9 1.1e-86 291.5 8.9 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_6 PF12774.7 EGF80885.1 - 2.9e-161 535.9 0.0 8.3e-159 527.8 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF80885.1 - 2.9e-143 477.8 1.9 2.9e-143 477.8 1.9 4.3 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGF80885.1 - 5.1e-113 377.3 0.2 1.9e-112 375.4 0.2 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGF80885.1 - 1.7e-103 345.5 0.2 1.4e-102 342.5 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGF80885.1 - 3.5e-90 301.0 5.3 5.9e-90 300.2 0.2 3.6 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF80885.1 - 6e-81 270.3 0.5 2.5e-75 252.0 0.0 3.6 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF80885.1 - 1.2e-63 213.8 1.8 3.8e-62 208.9 0.3 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF80885.1 - 2.7e-52 177.9 8.8 4.9e-52 177.1 8.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGF80885.1 - 7.9e-46 155.0 0.0 3e-44 149.9 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGF80885.1 - 1e-31 109.7 0.3 9e-31 106.6 0.0 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGF80885.1 - 7.9e-22 77.4 0.2 2.9e-21 75.5 0.2 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGF80885.1 - 3.6e-20 72.4 0.0 6.1e-06 26.3 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGF80885.1 - 1.1e-08 35.4 0.4 0.31 11.3 0.0 6.1 7 0 0 7 7 6 2 AAA domain AAA PF00004.29 EGF80885.1 - 1.5e-08 35.1 0.9 0.15 12.5 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF80885.1 - 3.3e-06 27.6 2.1 0.31 11.4 0.0 4.9 4 1 0 4 4 3 1 AAA ATPase domain DUF853 PF05872.12 EGF80885.1 - 1e-05 24.4 1.2 0.16 10.5 0.0 3.5 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 EGF80885.1 - 0.00011 22.7 0.1 0.7 10.4 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGF80885.1 - 0.00035 20.3 1.1 1.7 8.3 0.2 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGF80885.1 - 0.0005 20.4 0.1 3.1 8.2 0.0 4.1 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 EGF80885.1 - 0.00056 19.1 0.6 0.34 9.9 0.0 3.0 3 0 0 3 3 3 2 Type II/IV secretion system protein Sigma54_activat PF00158.26 EGF80885.1 - 0.0013 18.4 0.0 0.41 10.3 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.6 EGF80885.1 - 0.0034 17.7 0.3 39 4.5 0.0 4.7 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 EGF80885.1 - 0.0052 16.7 9.2 4 7.3 0.0 4.6 4 1 1 5 5 4 2 Rad17 P-loop domain ABC_tran PF00005.27 EGF80885.1 - 0.006 17.1 0.0 0.006 17.1 0.0 4.6 6 0 0 6 6 3 1 ABC transporter Mg_chelatase PF01078.21 EGF80885.1 - 0.012 14.9 0.6 8.2 5.7 0.0 4.3 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGF80885.1 - 0.079 12.9 0.8 35 4.3 0.0 4.4 4 0 0 4 4 4 0 NACHT domain FtsK_SpoIIIE PF01580.18 EGF80885.1 - 0.12 11.6 3.0 5.7 6.2 0.0 3.4 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EGF80885.1 - 0.53 10.4 2.4 24 5.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain UCH PF00443.29 EGF80886.1 - 7.6e-48 163.2 0.1 9.3e-48 163.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF80886.1 - 7.4e-15 55.3 0.4 1.1e-14 54.8 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGF80886.1 - 4.1e-09 36.0 0.2 8.5e-08 31.8 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family Phosphoesterase PF04185.14 EGF80887.1 - 2.8e-07 30.1 0.4 3.8e-07 29.6 0.4 1.1 1 0 0 1 1 1 1 Phosphoesterase family HpcH_HpaI PF03328.14 EGF80891.1 - 1.7e-44 151.6 0.0 2.5e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGF80891.1 - 8.6e-13 48.1 0.0 6.2e-12 45.3 0.0 2.1 1 1 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold IQ PF00612.27 EGF80892.1 - 1.9e-07 30.3 24.7 0.001 18.6 0.6 4.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif IF-2B PF01008.17 EGF80893.1 - 8.9e-71 238.4 3.3 1.1e-70 238.1 3.3 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CS PF04969.16 EGF80894.1 - 0.0036 18.3 0.1 0.0052 17.8 0.1 1.3 1 0 0 1 1 1 1 CS domain PIH1 PF08190.12 EGF80895.1 - 4.7e-48 162.8 0.1 1.6e-47 161.0 0.1 1.9 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGF80895.1 - 2.1e-21 76.2 0.0 2.3e-20 72.8 0.0 2.6 2 1 0 2 2 2 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EGF80895.1 - 0.02 14.5 0.1 2 8.0 0.0 2.8 1 1 1 2 2 2 0 HSP20-like domain found in ArsA SUKH_6 PF14568.6 EGF80895.1 - 0.041 14.3 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 EGF80895.1 - 0.11 12.2 1.6 5.9 6.6 0.0 3.3 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall DUF1615 PF07759.12 EGF80895.1 - 0.29 10.3 2.5 0.81 8.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1615) DUF2780 PF11075.8 EGF80895.1 - 0.38 10.9 3.4 0.69 10.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) SRP40_C PF05022.12 EGF80896.1 - 2.2e-28 98.9 4.3 2.2e-28 98.9 4.3 2.7 2 0 0 2 2 2 1 SRP40, C-terminal domain MWFE PF15879.5 EGF80897.1 - 2.3e-16 59.7 0.1 2.9e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Pkinase_Tyr PF07714.17 EGF80898.1 - 1.9e-32 112.6 0.0 6.1e-32 110.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGF80898.1 - 2.2e-28 99.3 0.0 5e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 EGF80898.1 - 4.5e-09 36.0 34.5 0.00017 21.3 4.8 5.3 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EGF80898.1 - 1.4e-08 34.9 36.7 0.0016 18.8 3.2 6.7 6 2 3 9 9 9 5 Leucine Rich repeats (2 copies) Peptidase_M36 PF02128.15 EGF80899.1 - 5.2e-137 456.9 0.0 5.9e-137 456.8 0.0 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Hydant_A_N PF05378.13 EGF80901.1 - 0.11 12.2 1.1 0.16 11.7 1.1 1.3 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF1168 PF06658.12 EGF80902.1 - 1.2e-33 115.8 6.9 1.2e-33 115.8 6.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) UPF0184 PF03670.13 EGF80902.1 - 0.016 15.6 2.8 2.2 8.7 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) DPPIV_N PF00930.21 EGF80903.1 - 5.3e-95 318.2 0.2 7.2e-95 317.7 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGF80903.1 - 5.9e-48 163.2 0.7 1.1e-47 162.3 0.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGF80903.1 - 2.3e-08 34.0 0.7 5e-08 32.9 0.7 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGF80903.1 - 0.0017 18.1 0.2 0.0033 17.1 0.2 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EGF80903.1 - 0.0022 17.7 0.2 0.0079 15.9 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGF80903.1 - 0.0094 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF80903.1 - 0.036 14.7 0.0 0.13 12.8 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family PD40 PF07676.12 EGF80903.1 - 0.056 13.4 0.2 28 4.8 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 EGF80903.1 - 0.084 12.8 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ResIII PF04851.15 EGF80904.1 - 0.11 12.5 1.1 0.26 11.3 1.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GDA1_CD39 PF01150.17 EGF80905.1 - 4.3e-88 295.8 0.0 5.9e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-RING_2 PF13639.6 EGF80906.1 - 9.5e-09 35.5 7.5 2.1e-08 34.4 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF80906.1 - 1.3e-08 34.6 8.8 2.6e-08 33.6 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF80906.1 - 1.3e-07 31.5 7.8 2.4e-07 30.6 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGF80906.1 - 4.6e-07 29.6 5.4 8.6e-07 28.7 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF80906.1 - 3.4e-05 23.6 7.8 7.3e-05 22.6 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF80906.1 - 5.7e-05 23.1 6.1 0.00017 21.6 6.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGF80906.1 - 7.8e-05 22.5 5.9 7.8e-05 22.5 5.9 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGF80906.1 - 0.0028 17.9 4.9 0.0079 16.5 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGF80906.1 - 0.025 14.3 4.3 0.053 13.3 4.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGF80906.1 - 0.1 12.8 6.1 0.2 11.8 6.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EGF80906.1 - 0.27 11.0 3.4 0.69 9.7 3.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 EGF80906.1 - 0.72 9.8 4.5 2.3 8.2 4.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGF80906.1 - 0.88 9.8 8.2 4.1 7.6 8.5 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_S9 PF00326.21 EGF80907.1 - 1.8e-08 34.1 0.1 1.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 EGF80907.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGF80907.1 - 0.0026 17.1 0.3 2 7.6 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 EGF80907.1 - 0.016 13.9 0.0 0.089 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.11 EGF80907.1 - 0.14 12.1 0.1 0.38 10.7 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 EGF80907.1 - 0.16 11.0 0.4 0.25 10.4 0.4 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 SET PF00856.28 EGF80908.1 - 0.12 12.7 0.2 0.6 10.5 0.2 2.1 1 1 0 1 1 1 0 SET domain Phospholamban PF04272.14 EGF80909.1 - 0.044 13.3 0.2 0.087 12.3 0.2 1.5 1 0 0 1 1 1 0 Phospholamban SNase PF00565.17 EGF80911.1 - 1.1e-05 25.8 0.0 0.0011 19.4 0.0 2.0 1 1 1 2 2 2 2 Staphylococcal nuclease homologue DUF1279 PF06916.13 EGF80912.1 - 1.1e-13 51.5 0.1 1.6e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Adaptin_N PF01602.20 EGF80913.1 - 4.2e-141 471.1 12.8 5.8e-141 470.6 12.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGF80913.1 - 4.7e-59 199.1 7.9 9.5e-58 194.8 0.5 4.0 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF80913.1 - 1.4e-15 57.5 3.3 1.4e-06 28.6 0.1 6.0 3 1 4 7 7 7 4 HEAT repeats HEAT PF02985.22 EGF80913.1 - 2.7e-11 42.7 6.4 0.0013 18.8 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat Alpha_adaptinC2 PF02883.20 EGF80913.1 - 5e-07 30.0 0.1 1.4e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd3 PF12719.7 EGF80913.1 - 0.00032 20.0 0.8 0.016 14.4 0.1 2.9 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EGF80913.1 - 0.00056 20.1 5.2 4.8 7.4 0.0 5.2 1 1 2 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm_2 PF04826.13 EGF80913.1 - 0.0022 17.5 0.0 0.0072 15.8 0.0 1.9 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 EGF80913.1 - 0.0042 17.1 1.4 0.61 10.2 0.1 4.0 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGF80913.1 - 0.02 14.4 2.9 0.15 11.6 0.0 3.8 5 1 0 5 5 5 0 CLASP N terminal HEAT_EZ PF13513.6 EGF80913.1 - 0.027 15.0 1.1 2.9 8.5 0.0 4.7 5 1 1 6 6 6 0 HEAT-like repeat Flu_M1_C PF08289.11 EGF80913.1 - 0.17 12.1 0.4 0.56 10.4 0.4 1.9 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain WD40 PF00400.32 EGF80914.1 - 6.6e-12 45.8 1.8 0.015 16.2 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF80914.1 - 0.0057 16.9 0.1 7.8 6.9 0.0 3.9 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EGF80914.1 - 0.036 13.4 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal UPRTase PF14681.6 EGF80915.1 - 1.7e-76 256.3 0.0 2.1e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGF80915.1 - 0.002 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Amidohydro_2 PF04909.14 EGF80916.1 - 2e-06 27.8 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EGF80916.1 - 9.5e-06 25.2 0.1 2.9e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family Helicase_C_2 PF13307.6 EGF80917.1 - 3.1e-52 177.2 0.0 8.3e-52 175.8 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGF80917.1 - 1.5e-45 155.0 0.3 2.5e-45 154.2 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 EGF80917.1 - 1e-05 25.4 0.1 0.0026 17.6 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGF80917.1 - 4.2e-05 23.6 0.2 0.00035 20.6 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EGF80917.1 - 0.00065 19.2 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.29 EGF80917.1 - 0.0012 19.2 0.3 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HBB PF06777.11 EGF80917.1 - 0.0026 17.5 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain SNF2_N PF00176.23 EGF80917.1 - 0.0051 15.6 0.2 0.018 13.8 0.2 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EGF80917.1 - 0.0069 16.7 0.2 3.6 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGF80917.1 - 0.017 15.5 0.0 0.047 14.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF434 PF04256.12 EGF80917.1 - 0.025 14.2 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF434) AAA_11 PF13086.6 EGF80917.1 - 0.033 14.0 1.0 0.13 12.0 1.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF80917.1 - 0.12 12.1 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EGF80918.1 - 8.7e-21 74.5 0.0 6.3e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 EGF80918.1 - 1.1e-20 73.4 0.3 2.8e-20 72.2 0.3 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EGF80918.1 - 1.6e-18 67.2 7.7 3.5e-18 66.1 7.7 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 EGF80918.1 - 4.8e-18 65.5 0.0 7.2e-17 61.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF80918.1 - 0.016 15.2 0.0 0.16 12.0 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3654 PF12376.8 EGF80918.1 - 0.39 10.9 6.2 0.87 9.8 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3654) PPR_long PF17177.4 EGF80919.1 - 7.5e-09 35.3 0.2 0.00059 19.3 0.0 2.8 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGF80919.1 - 2.5e-08 33.9 1.3 0.13 12.4 0.1 5.2 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF80919.1 - 2.6e-07 30.7 11.6 0.14 12.3 0.0 6.4 6 1 2 8 8 8 3 PPR repeat family PPR PF01535.20 EGF80919.1 - 3.8e-07 29.9 14.0 0.33 11.3 0.0 8.4 9 0 0 9 9 9 2 PPR repeat DUF3048 PF11258.8 EGF80919.1 - 0.068 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain BAR_3 PF16746.5 EGF80920.1 - 6.9e-47 160.2 0.8 1.4e-46 159.2 0.8 1.5 1 0 0 1 1 1 1 BAR domain of APPL family VASt PF16016.5 EGF80920.1 - 3.7e-29 102.1 0.7 7.8e-29 101.1 0.7 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 EGF80920.1 - 1.3e-16 61.0 1.9 1.9e-15 57.2 0.1 3.1 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 EGF80920.1 - 2.3e-08 34.4 0.1 2.3e-07 31.2 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain GRAM PF02893.20 EGF80920.1 - 2.9e-07 30.4 0.6 9.6e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 GRAM domain PH_8 PF15409.6 EGF80920.1 - 0.00026 21.2 0.7 0.00082 19.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGF80920.1 - 0.0022 18.4 0.4 0.012 16.1 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 EGF80920.1 - 0.066 12.9 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 PH domain Peptidase_M36 PF02128.15 EGF80921.1 - 1.6e-124 415.9 2.7 1.8e-124 415.7 2.7 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Tom6 PF17112.5 EGF80922.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Ecl1 PF12855.7 EGF80923.1 - 0.0015 19.7 27.1 0.003 18.7 27.1 1.7 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 EGF80923.1 - 0.011 16.3 2.1 0.029 15.0 2.1 1.7 1 0 0 1 1 1 0 PLATZ transcription factor Spectrin_like PF18373.1 EGF80923.1 - 0.033 14.3 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Spectrin like domain zf-MYND PF01753.18 EGF80923.1 - 0.46 10.6 3.8 1.3 9.2 3.8 1.8 1 1 0 1 1 1 0 MYND finger C2 PF00168.30 EGF80924.1 - 6.6e-27 93.8 0.4 1.7e-14 54.0 0.0 3.5 2 1 0 3 3 3 2 C2 domain Membr_traf_MHD PF10540.9 EGF80924.1 - 1.5e-14 54.4 0.4 2e-11 44.3 0.4 2.7 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 EGF80924.1 - 0.0017 18.7 0.2 0.0048 17.3 0.2 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) DUF810 PF05664.11 EGF80924.1 - 0.0072 14.9 1.0 0.018 13.6 1.0 1.6 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) NDUFB10 PF10249.9 EGF80926.1 - 0.00067 20.2 0.2 0.00067 20.2 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 YbjQ_1 PF01906.17 EGF80927.1 - 0.096 13.3 0.0 0.33 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative heavy-metal-binding AKNA PF12443.8 EGF80928.1 - 0.0069 17.0 2.9 0.024 15.3 0.1 2.9 2 0 0 2 2 2 1 AT-hook-containing transcription factor Bcr-Abl_Oligo PF09036.10 EGF80928.1 - 0.048 13.7 0.5 0.048 13.7 0.5 2.4 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 EGF80928.1 - 2.9 6.7 18.4 1.2 8.0 0.5 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EGF80928.1 - 3.7 8.1 6.3 35 4.9 0.3 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein JIP_LZII PF16471.5 EGF80928.1 - 7.2 6.9 9.5 3.5 7.9 0.5 3.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Adaptin_N PF01602.20 EGF80929.1 - 3.3e-124 415.3 0.3 4.1e-124 415.0 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGF80929.1 - 3.6e-54 183.2 0.9 1.2e-50 171.7 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF80929.1 - 2.4e-13 50.3 0.8 4.2e-06 27.0 0.0 5.4 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EGF80929.1 - 2.2e-10 39.9 2.3 0.16 12.3 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 EGF80929.1 - 7.9e-07 28.9 3.7 0.05 13.7 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EGF80929.1 - 3.8e-05 23.3 0.1 9.8e-05 21.9 0.1 1.7 1 1 0 1 1 1 1 Armadillo-like Cnd3 PF12719.7 EGF80929.1 - 0.0051 16.0 1.0 0.15 11.3 0.0 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EGF80929.1 - 0.0068 16.9 4.1 18 6.0 0.1 5.5 5 1 1 6 6 6 0 HEAT-like repeat RTP1_C1 PF10363.9 EGF80929.1 - 0.023 14.8 0.6 9.1 6.5 0.0 4.3 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 VHS PF00790.19 EGF80929.1 - 0.027 14.3 0.2 0.26 11.1 0.0 2.7 4 0 0 4 4 4 0 VHS domain V-ATPase_H_C PF11698.8 EGF80929.1 - 0.048 13.8 0.5 21 5.2 0.0 3.6 3 0 0 3 3 3 0 V-ATPase subunit H Cofilin_ADF PF00241.20 EGF80930.1 - 2.7e-36 124.0 1.2 3.1e-36 123.8 1.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Vps52 PF04129.12 EGF80931.1 - 1.4e-136 456.2 17.1 1.8e-136 455.9 17.1 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family FAM184 PF15665.5 EGF80931.1 - 0.018 14.9 0.9 0.049 13.4 0.3 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B SART-1 PF03343.13 EGF80931.1 - 0.14 10.7 0.1 0.26 9.8 0.1 1.3 1 0 0 1 1 1 0 SART-1 family COG2 PF06148.11 EGF80931.1 - 0.39 10.8 6.7 1.6 8.8 2.0 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OPT PF03169.15 EGF80932.1 - 4e-133 445.3 52.0 4.4e-133 445.1 52.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DOPA_dioxygen PF08883.11 EGF80933.1 - 4.4e-26 91.1 0.0 5.8e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family ThrE PF06738.12 EGF80934.1 - 2.2e-35 122.2 23.3 5.9e-21 74.9 2.1 3.1 3 0 0 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 EGF80934.1 - 4.1e-05 23.7 12.2 4.1e-05 23.7 12.2 3.7 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE WW PF00397.26 EGF80935.1 - 8.1e-09 35.4 1.9 1.6e-08 34.5 1.9 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 EGF80935.1 - 1.2e-07 32.0 28.6 3.7e-07 30.5 28.6 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Abhydrolase_6 PF12697.7 EGF80936.1 - 1.7e-12 48.4 0.3 2.2e-12 48.1 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF80936.1 - 2.3e-07 30.3 0.1 3.1e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGF80936.1 - 2.4e-06 27.4 0.2 3.2e-06 27.0 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EGF80936.1 - 0.0015 18.3 0.6 0.0023 17.7 0.6 1.5 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 EGF80936.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.3 1 1 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 EGF80936.1 - 0.0081 16.0 0.2 0.023 14.5 0.1 1.7 1 1 1 2 2 2 1 Serine hydrolase LCAT PF02450.15 EGF80936.1 - 0.0082 15.4 0.0 0.0095 15.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGF80936.1 - 0.035 13.6 0.1 0.079 12.5 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 EGF80936.1 - 0.037 14.2 0.0 0.055 13.6 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 EGF80936.1 - 0.039 13.5 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.11 EGF80936.1 - 0.055 13.3 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.7 EGF80936.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EGF80936.1 - 0.13 11.8 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DnaJ PF00226.31 EGF80937.1 - 3.7e-20 71.8 1.3 5.9e-20 71.2 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain FLYWCH_N PF15423.6 EGF80938.1 - 0.029 14.5 0.7 0.075 13.2 0.7 1.7 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein Pkinase PF00069.25 EGF80939.1 - 6.8e-28 97.8 0.0 1.6e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80939.1 - 2.5e-15 56.5 0.0 8.5e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF80939.1 - 0.035 13.4 0.0 0.099 11.9 0.0 1.7 1 0 0 1 1 1 0 Kinase-like PAP_PilO PF06864.12 EGF80939.1 - 0.091 11.6 0.5 0.17 10.7 0.5 1.4 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Pyrophosphatase PF00719.19 EGF80940.1 - 9e-58 194.6 0.2 1.2e-57 194.2 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase AD PF09793.9 EGF80940.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Proteasome PF00227.26 EGF80942.1 - 2.8e-51 173.7 0.1 5.1e-51 172.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF80942.1 - 2.2e-15 56.0 0.1 3.8e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ANAPC10 PF03256.16 EGF80943.1 - 4.8e-55 186.1 0.3 5.9e-55 185.8 0.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EGF80943.1 - 0.056 13.6 0.1 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 F5/8 type C domain Acyl-CoA_dh_N PF02771.16 EGF80944.1 - 2.9e-29 102.0 0.0 6e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGF80944.1 - 5.5e-29 101.3 0.2 9.9e-29 100.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF80944.1 - 1.9e-20 72.9 0.0 3.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGF80944.1 - 8.8e-10 39.0 0.1 1.4e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SH3BGR PF04908.15 EGF80945.1 - 1.8e-11 44.1 0.1 4.2e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EGF80945.1 - 5.5e-09 36.1 0.0 9.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin LUC7 PF03194.15 EGF80946.1 - 4.8e-63 213.2 1.5 5.6e-63 212.9 1.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF4558 PF15104.6 EGF80947.1 - 1.1e-09 38.2 7.4 1.1e-09 38.2 7.4 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4558) BACK PF07707.15 EGF80947.1 - 0.0036 17.4 0.8 0.0062 16.6 0.6 1.5 1 1 0 1 1 1 1 BTB And C-terminal Kelch SIKE PF05769.11 EGF80947.1 - 0.0073 16.3 4.8 0.009 16.0 4.5 1.3 1 1 0 1 1 1 1 SIKE family PriA_C PF18074.1 EGF80947.1 - 0.13 13.0 1.2 0.22 12.4 0.4 1.8 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain Acyltransferase PF01553.21 EGF80948.1 - 2.3e-24 85.6 0.0 3e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase ATP-synt_ab PF00006.25 EGF80949.1 - 1.2e-67 227.6 0.0 1.7e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGF80949.1 - 7.4e-13 48.8 1.0 1.6e-12 47.7 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 EGF80949.1 - 0.09 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HAS-barrel PF09378.10 EGF80949.1 - 0.092 12.9 0.3 0.24 11.5 0.3 1.7 1 0 0 1 1 1 0 HAS barrel domain DUF3510 PF12022.8 EGF80950.1 - 3.8e-36 124.2 0.1 1.2e-35 122.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 EGF80950.1 - 1.5e-25 89.8 1.0 1.5e-25 89.8 1.0 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1729 PF08354.10 EGF80950.1 - 0.00066 18.7 0.3 0.0032 16.4 0.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1729) Vps51 PF08700.11 EGF80950.1 - 0.011 15.8 0.2 0.17 12.0 0.0 2.7 2 0 0 2 2 2 0 Vps51/Vps67 PX PF00787.24 EGF80950.1 - 0.12 12.3 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 PX domain DUF4279 PF14106.6 EGF80950.1 - 0.24 11.6 0.9 19 5.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) TcpS PF17456.2 EGF80950.1 - 2 8.4 5.9 0.32 11.0 1.1 2.2 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Baculo_PEP_C PF04513.12 EGF80950.1 - 3.4 7.7 7.6 1.1 9.2 0.5 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_11 PF13086.6 EGF80951.1 - 5.3e-68 229.6 0.7 5.3e-68 229.6 0.7 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EGF80951.1 - 2.7e-60 203.4 0.0 7.2e-60 202.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 EGF80951.1 - 7.6e-17 60.8 9.4 7.6e-17 60.8 9.4 2.1 2 0 0 2 2 2 1 SEN1 N terminal AAA_19 PF13245.6 EGF80951.1 - 5.7e-10 39.7 0.0 5.5e-09 36.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGF80951.1 - 4.4e-08 33.1 0.3 0.00078 19.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EGF80951.1 - 2.6e-07 30.6 0.4 0.1 12.3 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EGF80951.1 - 0.013 15.9 0.0 0.049 14.1 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF80951.1 - 0.056 13.7 0.1 4 7.7 0.1 3.3 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EGF80951.1 - 0.084 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 EGF80951.1 - 0.12 12.4 1.0 0.41 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 EGF80951.1 - 5.4 6.4 17.1 1.7 8.0 0.0 4.4 4 1 0 4 4 4 0 UvrD/REP helicase N-terminal domain ASH PF15780.5 EGF80952.1 - 2.1e-37 127.2 29.2 0.00047 20.3 0.0 19.8 21 1 1 22 22 22 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EGF80952.1 - 1.2e-14 54.1 8.1 0.26 11.3 0.1 14.2 16 0 0 16 16 16 4 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 EGF80952.1 - 3.2e-13 49.5 17.4 0.025 14.4 0.1 10.4 10 0 0 10 10 10 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 EGF80952.1 - 5.8e-11 42.5 19.9 0.063 13.5 0.0 10.6 12 0 0 12 12 12 4 Transmembrane protein 131-like PapD-like PF14874.6 EGF80952.1 - 7.1e-08 32.5 2.9 0.086 13.0 0.0 8.8 10 0 0 10 10 10 1 Flagellar-associated PapD-like DUF3324 PF11797.8 EGF80952.1 - 0.082 12.9 4.5 23 4.9 0.3 4.1 5 0 0 5 5 5 0 Protein of unknown function C-terminal (DUF3324) Cyclin_N PF00134.23 EGF80953.1 - 4.3e-12 45.9 0.3 4.5e-10 39.4 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 EGF80953.1 - 0.0022 18.0 0.1 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EGF80953.1 - 0.0073 16.7 0.4 0.024 15.0 0.4 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain RB_B PF01857.20 EGF80953.1 - 0.015 15.3 0.5 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 EGF80953.1 - 0.018 15.1 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain MFS_1 PF07690.16 EGF80954.1 - 4.1e-51 174.0 36.2 2.6e-36 125.3 7.3 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGF80954.1 - 1.3e-13 50.6 16.1 1.6e-09 37.1 0.0 3.0 2 1 1 3 3 3 3 MFS_1 like family Sugar_tr PF00083.24 EGF80954.1 - 4.1e-13 49.0 17.5 1.4e-08 34.1 4.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EGF80954.1 - 1.5e-06 26.8 13.8 0.025 12.9 0.0 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EGF80954.1 - 0.0038 15.7 2.4 0.0038 15.7 2.4 3.1 2 1 1 3 3 3 3 Transmembrane secretion effector CRPA PF05745.11 EGF80954.1 - 0.082 12.9 1.3 0.24 11.4 0.0 2.5 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) ECSCR PF15820.5 EGF80954.1 - 4.7 7.1 5.3 3.1 7.7 0.2 3.1 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator Pam17 PF08566.10 EGF80954.1 - 6.8 6.5 4.9 17 5.3 2.2 2.8 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 SET PF00856.28 EGF80955.1 - 8.1e-12 45.8 0.7 1.5e-11 44.9 0.1 1.7 2 0 0 2 2 2 1 SET domain Tat PF00539.18 EGF80955.1 - 0.077 13.2 2.6 0.23 11.6 2.6 1.8 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Methyltransf_16 PF10294.9 EGF80956.1 - 3.1e-37 128.0 0.0 4.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGF80956.1 - 0.2 11.5 0.0 1 9.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.6 EGF80957.1 - 2.2e-21 76.9 0.1 3.3e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EGF80957.1 - 8.7e-21 74.9 0.0 2e-20 73.7 0.0 1.6 2 0 0 2 2 2 1 Isochorismatase family Glyco_hydro_76 PF03663.14 EGF80958.1 - 4.5e-39 135.0 3.5 4e-38 131.9 3.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGF80958.1 - 0.0032 16.6 0.2 0.88 8.6 0.0 3.0 2 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 DUF2839 PF10999.8 EGF80958.1 - 0.031 14.6 0.6 0.087 13.2 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) PCI PF01399.27 EGF80959.1 - 3.4e-13 50.0 2.3 1.1e-12 48.4 0.1 2.7 3 1 0 3 3 3 1 PCI domain Pkinase PF00069.25 EGF80960.1 - 9.3e-61 205.5 0.0 1e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF80960.1 - 5e-30 104.6 0.0 5.8e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGF80960.1 - 2.7e-05 23.9 0.7 0.15 11.6 0.0 2.4 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGF80960.1 - 2.9e-05 23.5 0.0 0.00051 19.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGF80960.1 - 0.00012 21.5 0.3 0.00097 18.5 0.3 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF80960.1 - 0.0018 17.9 0.1 0.0025 17.4 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGF80960.1 - 0.012 14.6 0.1 0.017 14.1 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGF80960.1 - 0.014 15.3 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF80960.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Gln-synt_C PF00120.24 EGF80961.1 - 1.9e-78 263.9 0.0 3.7e-73 246.5 0.0 2.1 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Ponericin PF07442.11 EGF80961.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Ponericin PTPLA PF04387.14 EGF80962.1 - 7e-51 172.2 11.0 7e-51 172.2 11.0 1.9 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA ERO1 PF04137.15 EGF80963.1 - 5e-126 420.7 3.4 5.7e-126 420.5 3.4 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Methyltransf_16 PF10294.9 EGF80964.1 - 2.3e-13 50.2 0.0 3.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGF80964.1 - 1.6e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGF80964.1 - 8.2e-10 38.6 0.4 1e-09 38.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGF80964.1 - 2.4e-06 28.2 0.1 5.6e-06 27.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGF80964.1 - 0.00037 20.1 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGF80964.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF80964.1 - 0.0096 16.6 0.0 0.022 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGF80964.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 EGF80964.1 - 0.01 16.6 0.0 0.015 16.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EGF80964.1 - 0.03 13.6 0.1 0.069 12.5 0.1 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltrans_SAM PF10672.9 EGF80964.1 - 0.05 12.7 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase PG_binding_1 PF01471.18 EGF80965.1 - 2.5e-05 24.4 0.0 6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Putative peptidoglycan binding domain BLOC1_2 PF10046.9 EGF80965.1 - 0.00064 20.0 0.0 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 EGF80965.1 - 0.079 13.5 0.1 0.4 11.3 0.1 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Med9 PF07544.13 EGF80965.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Acetyltransf_3 PF13302.7 EGF80966.1 - 2.9e-25 89.6 0.0 3.4e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF80966.1 - 1.4e-07 31.8 0.0 1.7e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGF80966.1 - 5.5e-06 26.3 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EGF80966.1 - 0.00012 21.8 0.1 0.00044 20.0 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF80966.1 - 0.02 15.3 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGF80966.1 - 0.023 14.8 0.2 0.038 14.1 0.0 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGF80966.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Ras PF00071.22 EGF80967.1 - 1.1e-53 181.1 0.1 1.4e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF80967.1 - 1.6e-30 105.8 0.3 2.4e-30 105.2 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF80967.1 - 5.5e-15 55.3 0.1 6.8e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF80967.1 - 1.2e-06 28.5 0.1 6.8e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF80967.1 - 2e-05 24.2 0.3 5.3e-05 22.9 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGF80967.1 - 8e-05 22.1 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGF80967.1 - 0.00044 19.7 0.0 0.00065 19.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EGF80967.1 - 0.00081 19.2 0.5 0.0012 18.6 0.5 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF80967.1 - 0.0066 16.4 0.0 0.022 14.7 0.0 1.9 1 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGF80967.1 - 0.0072 16.7 0.0 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGF80967.1 - 0.0096 16.4 0.0 0.021 15.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGF80967.1 - 0.015 15.1 1.2 0.037 13.8 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain G-alpha PF00503.20 EGF80967.1 - 0.016 14.4 0.9 0.58 9.3 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EGF80967.1 - 0.023 15.1 0.0 0.13 12.6 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EGF80967.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin MCM PF00493.23 EGF80967.1 - 0.046 12.8 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 EGF80967.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF80967.1 - 0.086 12.3 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGF80967.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Phage_fiber PF03335.13 EGF80967.1 - 0.12 12.6 3.4 0.33 11.2 3.4 1.8 1 0 0 1 1 1 0 Phage tail fibre repeat TniB PF05621.11 EGF80967.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Glyco_hydro_47 PF01532.20 EGF80968.1 - 1.4e-122 409.9 3.0 1.7e-122 409.6 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2408 PF10303.9 EGF80969.1 - 1e-53 181.5 0.6 1.3e-27 97.0 0.0 4.6 1 1 4 5 5 5 5 Protein of unknown function (DUF2408) V-SNARE PF05008.15 EGF80969.1 - 0.11 12.9 0.2 1 9.8 0.1 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus RE_EcoO109I PF14511.6 EGF80969.1 - 0.13 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I FUSC PF04632.12 EGF80969.1 - 0.27 9.7 0.6 0.52 8.8 0.3 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family Acyl-CoA_dh_1 PF00441.24 EGF80970.1 - 1.9e-50 170.9 3.1 1.9e-50 170.9 3.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF80970.1 - 2.1e-27 95.2 0.5 4.5e-27 94.1 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGF80970.1 - 4.5e-25 88.5 0.0 9e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF80970.1 - 8e-21 74.7 2.0 1.3e-20 74.0 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGF80970.1 - 0.0016 18.1 0.1 0.005 16.5 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PPR_3 PF13812.6 EGF80971.1 - 1.9e-09 37.5 0.5 0.014 15.5 0.0 5.1 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF80971.1 - 3.8e-06 27.0 6.2 0.053 13.7 0.0 5.4 6 1 1 7 7 7 2 PPR repeat family PPR PF01535.20 EGF80971.1 - 7.4e-05 22.7 1.7 6.8 7.2 0.0 5.5 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EGF80971.1 - 0.0001 21.7 0.3 0.0074 15.7 0.1 2.3 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 EGF80971.1 - 0.00096 19.0 1.3 0.027 14.3 0.0 3.1 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_14 PF13428.6 EGF80971.1 - 0.013 16.2 0.0 44 5.3 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat MvaI_BcnI PF15515.6 EGF80971.1 - 0.018 14.9 0.2 0.036 13.9 0.2 1.5 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family TPR_2 PF07719.17 EGF80971.1 - 0.072 13.2 1.4 1.2e+02 3.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF80971.1 - 0.14 12.5 2.4 27 5.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF80971.1 - 0.31 10.9 1.1 32 4.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Borrelia_rep PF03183.13 EGF80974.1 - 1.6 8.8 5.4 4 7.6 0.1 3.6 3 0 0 3 3 3 0 Borrelia repeat protein 1-cysPrx_C PF10417.9 EGF80975.1 - 0.031 14.1 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin MOSP_C PF02722.15 EGF80975.1 - 0.15 11.7 0.2 20 4.8 0.0 2.3 2 0 0 2 2 2 0 Major Outer Sheath Protein C-terminal domain Aldedh PF00171.22 EGF80976.1 - 8.6e-73 245.4 0.0 6e-72 242.6 0.0 1.8 1 1 0 1 1 1 1 Aldehyde dehydrogenase family RasGEF PF00617.19 EGF80978.1 - 2.5e-54 184.2 0.3 5.7e-54 183.0 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGF80978.1 - 4.2e-23 81.6 0.0 2.1e-22 79.4 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 EGF80978.1 - 5.1e-14 51.6 0.0 1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF80978.1 - 5.8e-13 48.3 0.0 1.2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGF80978.1 - 1.6e-12 47.1 0.0 3.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EGF80978.1 - 0.0034 17.5 3.2 0.012 15.7 3.2 2.1 1 0 0 1 1 1 1 WW domain GIT1_C PF12205.8 EGF80978.1 - 0.68 10.1 4.6 10 6.2 0.0 4.1 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term Phage-Gp8 PF09215.10 EGF80979.1 - 0.16 11.0 2.3 0.22 10.6 2.3 1.1 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 HNH_2 PF13391.6 EGF80980.1 - 8.1e-05 22.7 0.0 0.00028 20.9 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGF80980.1 - 0.29 11.3 2.3 2 8.6 2.3 2.3 1 1 0 1 1 1 0 HNH endonuclease DUF4435 PF14491.6 EGF80981.1 - 0.0043 17.0 4.1 0.0078 16.1 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4435) PhoU_div PF01865.16 EGF80981.1 - 0.047 13.0 3.6 0.85 8.9 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF47 DUF4191 PF13829.6 EGF80981.1 - 0.096 12.0 0.2 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Trypsin_2 PF13365.6 EGF80982.1 - 0.023 15.6 1.0 0.028 15.3 1.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.26 EGF80982.1 - 0.063 13.1 0.6 0.064 13.1 0.6 1.1 1 0 0 1 1 1 0 Trypsin ATP-synt_C PF00137.21 EGF80985.1 - 1.1 9.7 4.9 1.4 9.3 1.6 2.3 2 0 0 2 2 2 0 ATP synthase subunit C Utp14 PF04615.13 EGF80985.1 - 7.7 5.0 20.3 8.7 4.8 20.3 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.6 EGF80985.1 - 8.8 6.8 23.8 11 6.5 23.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Shisa PF13908.6 EGF80986.1 - 0.21 11.8 5.7 0.25 11.5 5.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EGF80986.1 - 2 8.3 6.2 3 7.8 6.1 1.4 1 1 0 1 1 1 0 TMEM154 protein family Abhydrolase_1 PF00561.20 EGF80987.1 - 1.1e-35 123.5 0.2 1.6e-35 123.0 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF80987.1 - 4.7e-15 55.5 0.0 1.1e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF80987.1 - 6.7e-09 36.7 0.2 8.9e-09 36.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGF80987.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 EGF80987.1 - 0.0014 17.4 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 EGF80987.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Myb_DNA-bind_6 PF13921.6 EGF80988.1 - 2.1e-06 27.9 1.2 0.26 11.6 0.0 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGF80988.1 - 0.002 18.3 3.1 2.3 8.5 0.1 3.5 3 1 0 3 3 3 2 Myb-like DNA-binding domain Aa_trans PF01490.18 EGF80991.1 - 4.9e-80 269.2 32.9 6.4e-80 268.9 32.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cortexin PF11057.8 EGF80991.1 - 0.064 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Cortexin of kidney PX PF00787.24 EGF80992.1 - 4.8e-11 42.6 0.8 6.6e-11 42.2 0.2 1.5 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 EGF80992.1 - 3.5e-07 29.8 0.1 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EGF80992.1 - 1.9e-05 24.4 0.0 5.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGF80992.1 - 0.00022 20.7 0.1 0.00063 19.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain PB1 PF00564.24 EGF80992.1 - 0.0011 18.8 0.2 0.002 18.0 0.2 1.4 1 0 0 1 1 1 1 PB1 domain RRM_1 PF00076.22 EGF80994.1 - 4.3e-28 96.9 0.0 1e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF80994.1 - 0.00086 19.1 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGF80994.1 - 0.0028 17.7 0.0 0.026 14.6 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 EGF80994.1 - 0.033 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Voltage_CLC PF00654.20 EGF80995.1 - 3.3e-89 299.6 30.0 5.6e-89 298.8 30.0 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EGF80995.1 - 6.1e-08 33.0 0.1 0.0021 18.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain Defensin_RK-1 PF17860.1 EGF80995.1 - 0.2 12.1 1.6 0.49 10.9 1.6 1.6 1 0 0 1 1 1 0 RK-1-like defensin Sporozoite_P67 PF05642.11 EGF80995.1 - 9.9 4.1 13.1 1.7 6.7 7.5 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ribosomal_L23eN PF03939.13 EGF80996.1 - 9.5e-15 54.5 5.5 2.1e-14 53.4 5.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGF80996.1 - 2.4e-14 53.4 6.1 5.2e-14 52.4 1.5 2.7 2 1 0 2 2 2 1 Ribosomal protein L23 zf-C3HC4_3 PF13920.6 EGF80998.1 - 8.1e-10 38.4 11.2 1.5e-09 37.5 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF80998.1 - 1.9e-08 34.0 9.8 3.3e-08 33.2 9.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Guanylate_cyc PF00211.20 EGF80999.1 - 1.2e-61 207.6 1.8 8.1e-33 113.6 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain BST2 PF16716.5 EGF81000.1 - 3.9 8.1 11.8 13 6.5 1.0 3.5 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 FapA PF03961.13 EGF81000.1 - 5.7 5.4 11.7 4.4 5.8 9.5 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Pkinase PF00069.25 EGF81001.1 - 2.6e-09 36.9 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGF81001.1 - 7.3e-05 22.4 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EGF81001.1 - 0.001 18.0 0.0 0.0053 15.6 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase NTP_transf_9 PF04248.12 EGF81001.1 - 0.09 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) AAA PF00004.29 EGF81002.1 - 4.3e-16 59.5 0.0 7.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF81002.1 - 1.1e-10 41.9 0.0 2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EGF81002.1 - 5.1e-10 39.4 0.1 1e-09 38.4 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EGF81002.1 - 1.6e-08 35.1 0.0 7.9e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EGF81002.1 - 3.1e-05 24.3 0.0 9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.14 EGF81002.1 - 9.3e-05 21.8 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase DUF2075 PF09848.9 EGF81002.1 - 0.0051 16.1 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGF81002.1 - 0.0052 16.5 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGF81002.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 EGF81002.1 - 0.0092 15.9 0.0 0.021 14.7 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGF81002.1 - 0.037 13.5 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EGF81002.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Kinesin PF00225.23 EGF81002.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain WD40 PF00400.32 EGF81003.1 - 2e-15 56.9 7.1 0.0011 19.8 0.7 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81003.1 - 4.8e-09 36.4 0.1 7.1e-05 23.0 0.0 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_2 PF07716.15 EGF81003.1 - 9e-09 35.3 10.3 1.8e-08 34.3 10.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper WD40_like PF17005.5 EGF81003.1 - 2.7e-05 23.6 0.0 0.0024 17.3 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain DSHCT PF08148.12 EGF81003.1 - 0.0045 16.7 0.6 0.0077 15.9 0.0 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain Cytochrom_D1 PF02239.16 EGF81003.1 - 0.021 13.4 0.0 0.79 8.2 0.0 2.4 3 0 0 3 3 3 0 Cytochrome D1 heme domain Fib_alpha PF08702.10 EGF81003.1 - 0.1 12.8 0.9 0.26 11.5 0.9 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FlgT_N PF16548.5 EGF81003.1 - 0.14 12.7 0.6 0.44 11.2 0.6 1.8 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain Pkinase PF00069.25 EGF81004.1 - 4.9e-66 222.8 0.0 6.2e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81004.1 - 3.6e-37 128.0 0.0 4.6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81004.1 - 2.2e-10 40.4 0.0 3.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF81004.1 - 6e-05 22.5 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF81004.1 - 0.00024 20.0 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF81004.1 - 0.00036 20.5 0.2 0.015 15.2 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF81004.1 - 0.0039 16.2 0.0 0.0065 15.4 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGF81004.1 - 0.027 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EGF81004.1 - 0.094 12.3 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Inhibitor_Mig-6 PF11555.8 EGF81004.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Brix PF04427.18 EGF81005.1 - 2e-30 106.4 0.2 2.7e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.32 EGF81006.1 - 2.2e-38 129.6 23.5 1e-05 26.2 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGF81006.1 - 3.3e-14 52.5 0.7 7.1e-14 51.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF81006.1 - 4.3e-10 39.2 0.4 1.2e-09 37.8 0.4 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EGF81006.1 - 7.5e-10 38.1 8.1 0.027 13.2 0.3 4.9 3 1 1 5 5 5 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 EGF81006.1 - 1.6e-05 24.8 0.0 0.0034 17.2 0.0 2.8 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EGF81006.1 - 0.00012 21.5 0.1 0.17 11.2 0.0 2.3 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGF81006.1 - 0.0025 16.8 4.0 0.52 9.2 0.3 3.5 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L15e PF00827.17 EGF81007.1 - 1.5e-90 302.1 9.2 1.7e-90 301.9 9.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Diphthamide_syn PF01866.17 EGF81008.1 - 9.6e-88 294.5 0.1 1.3e-87 294.1 0.1 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Complex1_LYR_2 PF13233.6 EGF81009.1 - 1.7e-18 67.1 0.3 2.2e-18 66.8 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGF81009.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) WGR PF05406.15 EGF81009.1 - 0.019 15.0 0.2 0.15 12.2 0.0 2.1 2 1 0 2 2 2 0 WGR domain DSBA PF01323.20 EGF81009.1 - 0.028 14.2 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Sel1 PF08238.12 EGF81010.1 - 1.5e-23 82.7 3.5 5.7e-07 30.0 0.1 7.5 7 0 0 7 7 7 5 Sel1 repeat Ribosomal_L36e PF01158.18 EGF81011.1 - 1.1e-41 141.0 7.6 1.2e-41 140.8 7.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RMI1_C PF16099.5 EGF81011.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold TetR_C_9 PF14514.6 EGF81011.1 - 0.08 13.1 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Mg_trans_NIPA PF05653.14 EGF81012.1 - 2.2e-57 194.4 12.9 2.6e-57 194.2 12.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGF81012.1 - 0.0016 18.6 4.4 0.0016 18.6 4.4 2.5 2 1 0 2 2 2 1 EamA-like transporter family zf-TFIIIC PF12660.7 EGF81013.1 - 8e-14 51.4 0.2 2.5e-13 49.9 0.2 1.9 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 EGF81013.1 - 2.4e-09 37.4 1.6 1.7e-06 28.1 1.6 2.7 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term PB1 PF00564.24 EGF81014.1 - 9.6e-09 35.1 0.2 1.7e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 PB1 domain RNF220 PF15926.5 EGF81015.1 - 6.9e-23 81.5 0.3 1.3e-22 80.7 0.3 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 EGF81015.1 - 3.3e-10 39.6 12.4 3.3e-10 39.6 12.4 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF81015.1 - 0.00016 21.5 8.8 0.00016 21.5 8.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF81015.1 - 0.0012 18.7 10.8 0.0026 17.6 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF81015.1 - 0.0013 18.5 9.2 0.0013 18.5 9.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF81015.1 - 0.0046 17.3 12.1 0.0046 17.3 12.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 EGF81015.1 - 0.033 14.2 3.6 0.033 14.2 3.6 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGF81015.1 - 0.096 12.6 8.6 0.24 11.3 8.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF81015.1 - 0.14 12.2 9.3 0.41 10.7 9.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EGF81015.1 - 0.48 10.3 7.7 1.2 9.0 7.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGF81015.1 - 0.91 9.4 5.1 1.7 8.5 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 EGF81015.1 - 5.2 7.2 10.6 19 5.3 5.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon Tubulin_3 PF14881.6 EGF81016.1 - 1.2e-29 103.3 0.0 2.5e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGF81016.1 - 4.1e-19 69.0 0.1 8.7e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EGF81016.1 - 1.3e-07 32.0 0.0 3.4e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 Tubulin/FtsZ family, GTPase domain NPV_P10 PF05531.12 EGF81018.1 - 2.5 8.6 7.9 3.6 8.1 0.9 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein PAC2 PF09754.9 EGF81019.1 - 1.1e-17 64.7 0.0 1.4e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family RFC1 PF08519.12 EGF81020.1 - 8.9e-52 175.4 0.1 5.8e-50 169.5 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EGF81020.1 - 2.3e-12 47.1 0.0 4.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EGF81020.1 - 1.2e-11 45.2 0.0 5.2e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF81020.1 - 0.0001 22.6 0.0 0.00044 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGF81020.1 - 0.00068 19.6 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EGF81020.1 - 0.0012 18.6 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF81020.1 - 0.0068 16.8 0.0 0.15 12.4 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGF81020.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 EGF81020.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 EGF81020.1 - 0.067 12.5 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DDE_Tnp_IS66 PF03050.14 EGF81020.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Transposase IS66 family TniB PF05621.11 EGF81020.1 - 0.16 11.3 0.0 1.2 8.5 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein Peptidase_M14 PF00246.24 EGF81021.1 - 5.6e-70 236.4 0.0 8e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGF81021.1 - 4.8e-08 33.3 0.1 1.4e-07 31.8 0.1 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide IFT57 PF10498.9 EGF81022.1 - 1.4e-123 412.5 6.1 1.6e-123 412.3 6.1 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ZapB PF06005.12 EGF81022.1 - 6.6e-05 23.3 1.3 0.0002 21.7 0.2 2.3 2 0 0 2 2 2 1 Cell division protein ZapB FPP PF05911.11 EGF81022.1 - 0.00079 17.8 8.9 0.001 17.4 8.9 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.9 EGF81022.1 - 0.0015 18.8 4.5 0.003 17.8 2.5 2.5 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 EGF81022.1 - 0.007 15.3 7.0 0.0089 15.0 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Prominin PF05478.11 EGF81022.1 - 0.0086 14.1 4.9 0.012 13.6 4.9 1.1 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.12 EGF81022.1 - 0.0091 16.0 3.5 0.049 13.7 3.4 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EGF81022.1 - 0.013 14.8 2.1 0.029 13.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EGF81022.1 - 0.016 15.2 3.9 0.016 15.2 3.9 2.1 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGF81022.1 - 0.019 15.0 4.1 0.019 15.0 4.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 EGF81022.1 - 0.022 14.1 4.5 0.019 14.3 2.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 EGF81022.1 - 0.027 14.7 2.4 0.089 13.0 1.9 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Occludin_ELL PF07303.13 EGF81022.1 - 0.027 15.2 4.0 0.047 14.4 1.5 2.6 1 1 2 3 3 3 0 Occludin homology domain FapA PF03961.13 EGF81022.1 - 0.031 12.9 2.6 0.046 12.3 2.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 EGF81022.1 - 0.033 14.4 2.3 0.072 13.3 2.3 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 EGF81022.1 - 0.035 13.7 2.8 0.048 13.2 2.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EGF81022.1 - 0.038 12.9 6.8 0.054 12.4 5.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Lebercilin PF15619.6 EGF81022.1 - 0.043 13.5 4.9 0.069 12.8 4.9 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 EGF81022.1 - 0.043 12.0 9.5 0.11 10.6 8.8 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA KxDL PF10241.9 EGF81022.1 - 0.052 13.8 5.4 0.36 11.1 0.9 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein CENP-Q PF13094.6 EGF81022.1 - 0.077 13.2 1.8 1.2 9.3 1.8 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4164 PF13747.6 EGF81022.1 - 0.1 12.9 1.0 1.2 9.5 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) LPP PF04728.13 EGF81022.1 - 0.11 13.0 0.2 0.54 10.7 0.2 2.3 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Fmp27_SW PF10305.9 EGF81022.1 - 0.26 12.0 2.7 50 4.7 0.1 3.3 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 EGF81022.1 - 0.39 9.9 7.2 0.19 11.0 0.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 EGF81022.1 - 0.51 10.8 5.3 0.3 11.5 1.9 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BRE1 PF08647.11 EGF81022.1 - 0.67 10.1 5.2 2.1 8.4 0.2 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EGF81022.1 - 0.7 10.0 10.4 0.13 12.3 4.1 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IFT20 PF14931.6 EGF81022.1 - 0.71 10.1 7.3 2.6 8.2 7.3 1.9 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 FlaC_arch PF05377.11 EGF81022.1 - 0.96 9.9 5.2 1.9 8.9 0.5 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 EGF81022.1 - 2 8.8 9.8 0.24 11.8 0.4 3.3 4 0 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 EGF81022.1 - 2.6 8.5 7.2 0.95 9.9 1.3 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Syntaxin_2 PF14523.6 EGF81022.1 - 2.8 8.4 12.4 4.3 7.8 6.7 2.7 1 1 1 2 2 2 0 Syntaxin-like protein TMF_DNA_bd PF12329.8 EGF81022.1 - 2.9 7.9 5.5 1.5 8.9 0.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 EGF81022.1 - 3.6 7.6 9.4 0.96 9.5 5.3 2.3 2 1 0 2 2 1 0 Laminin Domain II Fib_alpha PF08702.10 EGF81022.1 - 4.1 7.6 11.0 7.5 6.7 9.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 EGF81022.1 - 5.7 6.2 8.1 8.6 5.6 8.1 1.2 1 0 0 1 1 1 0 FAM76 protein Sec34 PF04136.15 EGF81022.1 - 6.6 6.6 10.7 12 5.8 8.6 2.4 2 1 0 2 2 1 0 Sec34-like family DUF16 PF01519.16 EGF81022.1 - 6.6 7.3 10.6 4 8.0 7.9 2.1 1 1 0 2 2 1 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 EGF81022.1 - 8.8 6.3 11.2 4.9 7.2 2.2 3.2 2 1 1 3 3 2 0 Prefoldin subunit Reprolysin_4 PF13583.6 EGF81023.1 - 4.7e-37 127.6 0.4 8.1e-37 126.8 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGF81023.1 - 1.6e-36 126.3 4.9 4.9e-36 124.7 4.9 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EGF81023.1 - 9.3e-35 120.3 1.6 2e-34 119.2 1.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EGF81023.1 - 1.5e-14 54.5 28.5 1.5e-14 54.5 28.5 4.6 4 1 1 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 EGF81023.1 - 3.2e-14 53.5 0.0 6.1e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EGF81023.1 - 2.4e-05 24.3 5.8 0.00021 21.2 5.8 2.3 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 EGF81023.1 - 3.4e-05 24.1 0.1 7e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide DUF4713 PF15831.5 EGF81023.1 - 5.2 7.6 11.3 14 6.2 11.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) zf-C2H2_2 PF12756.7 EGF81024.1 - 1.2e-23 83.4 9.8 1.8e-21 76.4 3.9 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGF81024.1 - 6e-06 26.4 1.6 2.1e-05 24.6 1.6 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGF81024.1 - 0.01 16.2 6.2 0.27 11.8 1.3 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF81024.1 - 0.017 16.0 0.3 0.017 16.0 0.3 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger PyrI_C PF02748.15 EGF81024.1 - 0.031 14.2 0.1 0.085 12.8 0.1 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.7 EGF81024.1 - 0.04 14.3 3.6 0.081 13.4 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGF81024.1 - 0.045 13.5 0.2 0.045 13.5 0.2 2.7 2 1 0 2 2 2 0 zinc-finger C2H2-type Opiods_neuropep PF01160.18 EGF81024.1 - 0.57 10.3 2.4 0.76 9.9 0.6 2.0 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide zf-H2C2_2 PF13465.6 EGF81024.1 - 4.2 8.0 7.7 5.2 7.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain LSM PF01423.22 EGF81025.1 - 1e-19 70.0 1.0 1.3e-19 69.6 1.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF81025.1 - 0.028 14.6 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain LRR_6 PF13516.6 EGF81025.1 - 0.11 12.6 0.1 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Hfq PF17209.3 EGF81025.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Serglycin PF04360.12 EGF81026.1 - 0.0056 16.6 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Serglycin DUF1275 PF06912.11 EGF81027.1 - 5.8e-10 39.4 1.5 7.3e-10 39.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) OTT_1508_deam PF14441.6 EGF81028.1 - 3.8e-13 49.2 2.3 1e-12 47.9 1.5 2.2 2 0 0 2 2 2 1 OTT_1508-like deaminase HrcA PF01628.21 EGF81028.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 HrcA protein C terminal domain TAF1_subA PF14929.6 EGF81030.1 - 8.8e-14 51.7 2.4 1e-12 48.2 2.4 2.0 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A WD40 PF00400.32 EGF81031.1 - 1.2e-57 190.5 26.2 1.4e-06 28.9 0.0 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81031.1 - 9.3e-24 83.6 3.7 0.00024 21.3 0.0 9.6 5 3 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGF81031.1 - 1.4e-18 67.2 0.3 3.6e-18 65.8 0.3 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 EGF81031.1 - 4.8e-08 32.7 0.2 0.0077 15.6 0.0 4.3 4 2 1 6 6 6 3 WD40-like domain Nucleoporin_N PF08801.11 EGF81031.1 - 1.4e-05 24.1 3.8 0.37 9.5 0.0 5.7 3 2 3 7 7 7 1 Nup133 N terminal like Ge1_WD40 PF16529.5 EGF81031.1 - 2.3e-05 23.6 4.0 0.36 9.7 0.0 5.6 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EGF81031.1 - 0.0012 17.9 3.9 0.053 12.4 0.1 3.5 4 0 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Oxysterol_BP PF01237.18 EGF81032.1 - 5.9e-84 282.0 0.0 1.2e-81 274.4 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein WD40 PF00400.32 EGF81033.1 - 4.4e-48 160.3 26.0 4.9e-10 39.9 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81033.1 - 8.6e-22 77.3 1.9 0.00046 20.4 0.0 6.2 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EGF81033.1 - 6.7e-09 35.4 0.1 1.5e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 EGF81033.1 - 4.2e-05 23.5 2.5 0.15 11.9 0.2 3.9 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGF81033.1 - 0.00033 19.4 3.9 0.11 11.1 0.0 3.6 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF81033.1 - 0.02 13.8 0.4 3 6.7 0.0 3.6 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_6 PF13964.6 EGF81033.1 - 0.14 12.5 0.3 2.3 8.7 0.1 3.1 3 0 0 3 3 3 0 Kelch motif DPM2 PF07297.12 EGF81034.1 - 2.5e-30 104.6 2.3 2.7e-30 104.5 2.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGF81034.1 - 0.002 18.0 2.7 0.0024 17.8 2.7 1.1 1 0 0 1 1 1 1 PIG-P GrpE PF01025.19 EGF81035.1 - 5e-49 166.1 0.4 6.1e-49 165.9 0.4 1.0 1 0 0 1 1 1 1 GrpE Med21 PF11221.8 EGF81035.1 - 0.00048 20.4 2.0 0.00076 19.7 2.0 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Apt1 PF10351.9 EGF81035.1 - 0.0067 15.3 1.0 0.0082 15.0 1.0 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain MREG PF15812.5 EGF81035.1 - 0.03 14.6 0.6 0.041 14.2 0.6 1.1 1 0 0 1 1 1 0 Melanoregulin Clusterin PF01093.17 EGF81035.1 - 0.042 12.9 0.3 0.048 12.7 0.3 1.1 1 0 0 1 1 1 0 Clusterin PRP38 PF03371.15 EGF81035.1 - 0.055 13.3 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 PRP38 family DUF3606 PF12244.8 EGF81035.1 - 0.079 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) HIP1_clath_bdg PF16515.5 EGF81035.1 - 0.1 13.2 3.1 0.26 11.9 3.1 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 EGF81035.1 - 0.1 12.6 0.7 0.1 12.6 0.7 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding UQ_con PF00179.26 EGF81036.1 - 8.6e-42 142.1 0.0 9.6e-42 142.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EGF81036.1 - 0.0014 18.3 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EGF81036.1 - 0.0029 17.9 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGF81036.1 - 0.0047 16.6 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B NUDIX PF00293.28 EGF81037.1 - 1.1e-10 41.6 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EGF81038.1 - 3.1e-06 27.8 0.0 4.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Glycos_transf_1 PF00534.20 EGF81039.1 - 7.2e-09 35.4 0.0 1.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF81039.1 - 7.4e-09 36.1 0.0 4.2e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGF81039.1 - 0.00072 19.9 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGF81039.1 - 0.00093 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 EGF81039.1 - 0.088 12.8 0.1 0.25 11.4 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like zf-C3HC PF07967.13 EGF81040.1 - 9.9e-24 83.9 3.4 3.9e-21 75.5 0.1 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EGF81040.1 - 6.6e-15 55.0 0.6 6.6e-15 55.0 0.6 2.1 2 1 0 2 2 2 1 Rsm1-like Mog1 PF04603.12 EGF81040.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Ran-interacting Mog1 protein RasGEF PF00617.19 EGF81041.1 - 8.9e-52 175.8 2.1 3.2e-50 170.8 0.4 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGF81041.1 - 4.7e-19 68.6 0.4 2.2e-18 66.4 0.2 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Ank_2 PF12796.7 EGF81041.1 - 4.8e-12 46.3 0.1 2.3e-11 44.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGF81041.1 - 2e-10 40.0 0.2 0.00014 22.0 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGF81041.1 - 2.4e-10 40.4 0.8 0.00012 22.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGF81041.1 - 3.1e-09 37.2 2.1 0.00015 22.3 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGF81041.1 - 3.7e-09 36.6 1.9 9.2e-05 22.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat KIX PF02172.16 EGF81041.1 - 0.24 11.7 3.3 0.48 10.7 0.3 2.7 2 0 0 2 2 2 0 KIX domain Torus PF16131.5 EGF81042.1 - 2e-06 28.4 2.0 2.9e-06 27.9 0.5 2.1 3 0 0 3 3 3 1 Torus domain zf-CCCH PF00642.24 EGF81042.1 - 0.0023 17.8 1.4 0.0023 17.8 1.4 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGF81042.1 - 0.0029 17.4 0.6 0.0029 17.4 0.6 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGF81042.1 - 0.0096 16.0 0.9 0.0096 16.0 0.9 2.3 2 0 0 2 2 2 1 Zinc finger domain His_Phos_2 PF00328.22 EGF81043.1 - 9e-77 259.0 0.1 1.1e-76 258.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EGF81043.1 - 2.3e-35 120.6 0.1 5.3e-35 119.5 0.1 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGF81043.1 - 8.4e-09 35.3 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TetR_C_8 PF14278.6 EGF81043.1 - 0.14 12.3 0.1 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region MFS_MOT1 PF16983.5 EGF81044.1 - 3.5e-60 201.3 30.0 6.2e-34 116.7 7.2 2.5 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 EGF81044.1 - 1.7e-08 33.7 22.0 5.1e-07 28.8 22.0 2.5 1 1 0 1 1 1 1 Sulfate permease family DUF4131 PF13567.6 EGF81044.1 - 0.071 12.8 3.2 0.77 9.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TFIIB PF00382.19 EGF81045.1 - 2.6e-31 107.5 2.8 1.4e-20 73.1 1.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGF81045.1 - 1.2e-12 47.1 0.4 2.3e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EGF81045.1 - 0.0057 16.7 1.0 0.23 11.5 0.2 2.2 1 1 1 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 EGF81045.1 - 0.013 15.6 0.4 0.03 14.4 0.4 1.6 1 1 0 1 1 1 0 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 EGF81045.1 - 0.018 14.8 0.6 1.5 8.5 0.3 2.3 1 1 1 2 2 2 0 Cyclin, N-terminal domain UNC45-central PF11701.8 EGF81045.1 - 0.028 14.4 0.3 0.054 13.5 0.3 1.5 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF2039 PF10217.9 EGF81045.1 - 0.97 9.8 3.5 9.8 6.6 1.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) Keratin_2_head PF16208.5 EGF81046.1 - 0.0033 17.6 27.3 0.0089 16.2 23.6 2.4 2 0 0 2 2 2 1 Keratin type II head GPS2_interact PF15784.5 EGF81046.1 - 0.047 14.1 0.2 0.096 13.1 0.2 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DASH_Dad2 PF08654.10 EGF81046.1 - 0.18 12.2 3.3 0.36 11.3 0.6 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad2 KRTAP PF11759.8 EGF81046.1 - 1.1 9.9 54.5 3.8 8.1 50.0 2.6 2 1 0 2 2 2 0 Keratin-associated matrix WXG100 PF06013.12 EGF81046.1 - 1.1 9.5 4.4 8.3 6.7 0.5 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG WD40 PF00400.32 EGF81047.1 - 2.3e-25 88.3 11.7 6.8e-08 33.1 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81047.1 - 2.5e-17 63.0 0.0 4.7e-07 30.0 0.0 5.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF81047.1 - 2.3e-05 23.5 0.3 0.9 8.4 0.0 4.4 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGF81047.1 - 3.1e-05 23.9 0.2 0.1 12.5 0.0 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGF81047.1 - 0.0011 18.8 10.5 1 9.4 0.3 5.0 5 1 0 5 5 5 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 EGF81047.1 - 0.0032 17.4 0.9 0.88 9.5 0.2 3.1 1 1 2 3 3 3 2 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.9 EGF81047.1 - 0.0087 15.7 2.5 8.3 6.2 0.1 4.3 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature SGL PF08450.12 EGF81047.1 - 0.071 12.7 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DPPIV_N PF00930.21 EGF81048.1 - 6.8e-28 97.4 9.1 3.5e-27 95.1 3.8 3.0 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region SCNM1_acidic PF15805.5 EGF81048.1 - 0.22 11.3 6.6 0.58 9.9 0.1 2.9 3 0 0 3 3 3 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Penicillinase_R PF03965.16 EGF81049.1 - 0.065 13.6 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Penicillinase repressor Radial_spoke PF04712.12 EGF81050.1 - 2.9e-15 56.2 3.0 1.3e-06 27.7 0.0 3.4 1 1 2 3 3 3 3 Radial spokehead-like protein EF-hand_6 PF13405.6 EGF81051.1 - 0.00025 20.7 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGF81051.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGF81051.1 - 0.0084 16.5 0.0 0.0091 16.4 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair Beta-lactamase2 PF13354.6 EGF81051.1 - 0.036 13.7 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase enzyme family EF-hand_8 PF13833.6 EGF81051.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair NUDIX_2 PF13869.6 EGF81052.1 - 9e-73 243.9 0.0 1e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SSTK-IP PF15836.5 EGF81054.1 - 0.37 10.9 6.8 0.51 10.5 0.4 2.3 2 0 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Serglycin PF04360.12 EGF81055.1 - 0.0069 16.3 2.9 0.74 9.8 0.0 2.5 2 0 0 2 2 2 2 Serglycin GPS2_interact PF15784.5 EGF81055.1 - 0.036 14.5 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain KRTAP PF11759.8 EGF81055.1 - 0.047 14.2 17.9 0.14 12.7 13.5 2.4 2 0 0 2 2 2 0 Keratin-associated matrix DASH_Dad2 PF08654.10 EGF81055.1 - 0.17 12.3 1.5 0.98 9.9 0.2 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad2 Keratin_2_head PF16208.5 EGF81055.1 - 0.39 10.8 13.0 1.2 9.3 9.4 2.4 2 0 0 2 2 2 0 Keratin type II head WXG100 PF06013.12 EGF81055.1 - 1 9.6 3.7 14 5.9 0.3 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF1275 PF06912.11 EGF81056.1 - 4.2e-29 101.9 20.0 5.1e-29 101.6 20.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EGF81056.1 - 0.052 13.5 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 PIG-P GSH-S_ATP PF02955.16 EGF81057.1 - 0.0034 16.8 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain LRR_6 PF13516.6 EGF81058.1 - 6.2e-14 50.8 16.5 0.00051 19.9 1.5 6.7 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 EGF81058.1 - 0.0001 22.6 13.6 0.057 13.9 0.3 4.2 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF81058.1 - 0.0054 16.5 14.9 0.029 14.1 9.3 4.3 4 1 1 5 5 5 1 Leucine rich repeat PrpR_N PF06506.11 EGF81058.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Propionate catabolism activator LRR_1 PF00560.33 EGF81058.1 - 0.2 12.3 11.8 58 4.8 0.0 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat Polysacc_deac_1 PF01522.21 EGF81060.1 - 5.6e-19 68.3 0.0 1.1e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGF81060.1 - 3.4e-13 49.8 67.1 9.9e-06 25.9 16.8 3.8 3 0 0 3 3 3 3 Chitin recognition protein HC2 PF07382.11 EGF81060.1 - 3.3e-10 40.4 60.1 7.9e-10 39.1 60.1 1.6 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Neur_chan_memb PF02932.16 EGF81060.1 - 1.5 8.8 6.6 2.4 8.1 6.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 EGF81060.1 - 2.3 6.8 6.2 3.1 6.4 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phosphoesterase PF04185.14 EGF81061.1 - 7.1e-53 180.0 0.5 1e-52 179.5 0.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.14 EGF81062.1 - 6.6e-48 163.7 0.4 9.9e-48 163.1 0.4 1.2 1 0 0 1 1 1 1 Phosphoesterase family Septin PF00735.18 EGF81064.1 - 3.1e-105 351.5 0.1 3.6e-105 351.3 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGF81064.1 - 7e-08 32.5 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGF81064.1 - 6.1e-05 22.4 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGF81064.1 - 0.00017 21.5 0.1 0.00078 19.4 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGF81064.1 - 0.0002 20.8 0.1 0.00041 19.8 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 EGF81064.1 - 0.0027 18.1 0.1 0.0039 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGF81064.1 - 0.0036 16.5 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Ras PF00071.22 EGF81064.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 EGF81064.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGF81064.1 - 0.016 14.4 0.0 0.037 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGF81064.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 EGF81064.1 - 0.02 14.9 1.3 0.64 10.1 0.3 2.5 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.6 EGF81064.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGF81064.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 EGF81064.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FAM184 PF15665.5 EGF81065.1 - 0.094 12.5 76.1 0.11 12.2 12.8 5.1 4 1 0 4 4 4 0 Family with sequence similarity 184, A and B MFS_1 PF07690.16 EGF81066.1 - 5.1e-21 75.0 42.0 5.1e-21 75.0 42.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_16 PF10294.9 EGF81067.1 - 7.5e-09 35.6 0.0 2.8e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGF81067.1 - 0.00012 22.7 0.0 0.013 16.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGF81067.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EGF81067.1 - 0.0022 18.7 0.0 0.87 10.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGF81067.1 - 0.0027 18.3 0.0 0.025 15.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF81067.1 - 0.0086 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MFA1_2 PF17317.2 EGF81067.1 - 0.096 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 GTP_EFTU PF00009.27 EGF81068.1 - 6e-26 91.2 0.0 1.1e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGF81068.1 - 1.6e-17 63.5 0.1 5e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGF81068.1 - 1.3e-12 47.9 2.4 7.2e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EGF81068.1 - 8.8e-10 38.4 0.2 2.3e-09 37.1 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EGF81068.1 - 0.0028 17.7 0.0 0.048 13.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGF81068.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ribosomal_S7e PF01251.18 EGF81069.1 - 1.8e-84 282.1 4.1 2e-84 281.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e AAA PF00004.29 EGF81070.1 - 3.2e-59 199.1 0.0 4.7e-43 146.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF81070.1 - 3.4e-10 39.6 0.3 0.00076 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGF81070.1 - 8.3e-10 39.3 1.5 0.0071 16.7 0.1 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGF81070.1 - 3.8e-07 30.2 0.2 0.011 15.8 0.0 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGF81070.1 - 0.00013 22.1 0.0 0.0081 16.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGF81070.1 - 0.00015 22.0 0.1 0.0078 16.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGF81070.1 - 0.00017 20.9 0.0 0.025 13.8 0.0 2.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EGF81070.1 - 0.00017 21.7 0.0 0.36 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EGF81070.1 - 0.00025 20.8 0.0 0.0037 17.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGF81070.1 - 0.0003 21.1 0.0 0.032 14.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.21 EGF81070.1 - 0.0003 20.2 0.1 0.022 14.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGF81070.1 - 0.0003 20.5 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain TsaE PF02367.17 EGF81070.1 - 0.00051 20.0 0.0 0.47 10.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGF81070.1 - 0.0019 18.7 0.0 0.044 14.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGF81070.1 - 0.0036 17.1 0.0 0.095 12.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGF81070.1 - 0.0039 16.7 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Vps4_C PF09336.10 EGF81070.1 - 0.0045 17.0 0.1 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EGF81070.1 - 0.0046 16.6 1.1 0.2 11.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGF81070.1 - 0.0084 15.9 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EGF81070.1 - 0.024 14.5 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGF81070.1 - 0.03 14.4 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGF81070.1 - 0.063 12.6 0.1 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 KaiC Torsin PF06309.11 EGF81070.1 - 0.067 13.3 0.0 10 6.3 0.0 2.7 2 1 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 EGF81070.1 - 0.078 12.1 0.1 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 EGF81070.1 - 0.079 13.0 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 EGF81070.1 - 0.25 11.2 1.0 11 5.9 0.1 2.8 2 0 0 2 2 2 0 NACHT domain Voltage_CLC PF00654.20 EGF81071.1 - 3e-88 296.4 25.2 3e-88 296.4 25.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGF81071.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 CBS domain LRR19-TM PF15176.6 EGF81071.1 - 0.098 12.7 2.8 0.42 10.6 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain ALAD PF00490.21 EGF81072.1 - 1.5e-119 398.9 0.0 1.8e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-C2H2 PF00096.26 EGF81073.1 - 1.3e-07 31.7 24.1 0.0078 16.6 5.0 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF81073.1 - 2.4e-06 27.9 19.7 0.15 13.0 5.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF81073.1 - 8.4e-05 22.8 1.0 8.4e-05 22.8 1.0 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGF81073.1 - 0.0085 16.4 8.9 0.12 12.7 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGF81073.1 - 0.014 15.7 6.0 0.037 14.3 6.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EGF81073.1 - 0.19 12.1 2.1 78 3.9 0.7 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 EGF81073.1 - 0.38 10.9 3.1 1.1 9.4 2.3 2.2 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_8 PF15909.5 EGF81073.1 - 0.66 10.3 11.7 0.3 11.4 6.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 EGF81073.1 - 0.99 9.4 6.6 2 8.4 0.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 EGF81073.1 - 1.1 9.3 7.4 0.68 9.9 2.6 3.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 EGF81073.1 - 6.5 7.0 5.9 4.5 7.5 1.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Peptidase_M24 PF00557.24 EGF81074.1 - 2.8e-57 193.8 0.0 4.6e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGF81074.1 - 6.2e-33 113.1 0.0 1.1e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3684 PF12449.8 EGF81075.1 - 4.6e-251 836.0 7.8 5.6e-247 822.5 4.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EGF81075.1 - 0.00022 21.0 0.1 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TH1 PF04858.13 EGF81077.1 - 1e-44 153.2 0.0 1.3e-44 152.8 0.0 1.0 1 0 0 1 1 1 1 TH1 protein Na_Ca_ex PF01699.24 EGF81078.1 - 9.2e-17 61.4 43.5 2.8e-13 50.1 12.8 4.1 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EGF81078.1 - 8.6e-13 48.8 16.0 8.6e-13 48.8 16.0 5.3 7 0 0 7 7 7 2 Inner membrane component domain Peptidase_M36 PF02128.15 EGF81079.1 - 1.9e-124 415.6 5.9 2.1e-124 415.5 5.9 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF81079.1 - 0.0041 17.0 0.2 0.0096 15.8 0.1 1.8 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain GspH PF12019.8 EGF81079.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 Type II transport protein GspH CENP-H PF05837.12 EGF81080.1 - 0.0091 16.4 2.7 0.013 15.9 2.7 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF4407 PF14362.6 EGF81080.1 - 0.014 14.8 0.2 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FokI_C PF02980.16 EGF81080.1 - 0.038 14.0 0.6 0.054 13.5 0.6 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain MF_alpha_N PF05436.11 EGF81080.1 - 0.19 11.7 1.1 0.35 10.8 1.1 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF724 PF05266.14 EGF81080.1 - 0.32 10.8 5.5 0.43 10.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Holin_BhlA PF10960.8 EGF81080.1 - 4.4 7.3 7.1 9.3 6.3 1.9 2.7 1 1 2 3 3 3 0 BhlA holin family Chromo_shadow PF01393.19 EGF81083.1 - 1.2e-18 66.9 0.2 1.9e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 Chromo shadow domain PPL5 PF18168.1 EGF81083.1 - 0.51 9.6 5.4 0.37 10.0 3.5 1.6 1 1 1 2 2 2 0 Prim-pol family 5 DUF1539 PF07560.11 EGF81084.1 - 2.3e-05 24.5 17.3 0.033 14.3 0.8 5.0 2 2 3 5 5 5 4 Domain of Unknown Function (DUF1539) BET PF17035.5 EGF81084.1 - 0.00033 20.8 32.5 0.095 12.9 1.7 4.8 5 0 0 5 5 5 4 Bromodomain extra-terminal - transcription regulation EpuA PF11772.8 EGF81084.1 - 0.0057 16.3 9.1 28 4.5 0.1 5.0 5 0 0 5 5 5 3 DNA-directed RNA polymerase subunit beta MT-A70 PF05063.14 EGF81084.1 - 0.0068 16.3 1.0 0.92 9.4 0.2 2.3 2 0 0 2 2 2 2 MT-A70 SpecificRecomb PF10136.9 EGF81084.1 - 2.6 6.2 6.0 6.8 4.9 0.3 3.2 2 2 2 4 4 4 0 Site-specific recombinase RED_C PF07807.11 EGF81084.1 - 3.5 8.1 11.7 37 4.9 0.6 4.5 4 0 0 4 4 4 0 RED-like protein C-terminal region Spc7 PF08317.11 EGF81085.1 - 0.0024 16.8 1.2 0.0041 16.0 1.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Coatomer_WDAD PF04053.14 EGF81085.1 - 0.046 12.8 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region TPR_MLP1_2 PF07926.12 EGF81085.1 - 0.068 13.2 2.3 0.14 12.2 0.4 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 EGF81085.1 - 1.5 7.9 3.6 0.91 8.7 0.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein TerY_C PF15616.6 EGF81087.1 - 0.046 13.8 0.4 0.093 12.8 0.1 1.6 2 0 0 2 2 2 0 TerY-C metal binding domain Spc7 PF08317.11 EGF81089.1 - 0.25 10.2 7.7 0.021 13.7 1.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EGF81089.1 - 0.66 10.0 9.2 1.1 9.3 1.7 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Wbp11 PF09429.10 EGF81089.1 - 8.4 6.9 9.7 14 6.2 1.4 3.0 2 2 1 3 3 3 0 WW domain binding protein 11 Ribonuclease_3 PF00636.26 EGF81090.1 - 6.4e-18 65.3 0.1 1.9e-17 63.8 0.0 1.8 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF81090.1 - 7.3e-11 42.3 0.0 1.2e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGF81092.1 - 0.19 12.4 0.6 0.64 10.7 0.0 2.1 2 1 0 2 2 2 0 Ribonuclease III domain Ribosomal_L27A PF00828.19 EGF81095.1 - 9.2e-27 94.2 0.1 1.2e-26 93.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HTH_7 PF02796.15 EGF81096.1 - 1.4e-07 31.5 1.8 0.015 15.3 0.2 3.0 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EGF81096.1 - 4e-07 29.6 1.2 0.0077 16.0 0.1 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EGF81096.1 - 3.6e-06 27.0 1.0 0.013 15.6 0.1 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_33 PF13592.6 EGF81096.1 - 1.6e-05 24.4 0.2 1.6e-05 24.4 0.2 2.9 4 0 0 4 4 3 1 Winged helix-turn helix HTH_17 PF12728.7 EGF81096.1 - 1.7e-05 24.9 1.8 0.027 14.7 1.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 EGF81096.1 - 1.9e-05 24.7 1.0 0.12 12.5 0.1 2.3 2 0 0 2 2 2 2 Transposase HTH_32 PF13565.6 EGF81096.1 - 7.3e-05 23.3 3.8 0.00074 20.1 3.4 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_22 PF13309.6 EGF81096.1 - 0.00075 19.5 0.2 0.068 13.3 0.2 2.8 2 1 0 2 2 2 1 HTH domain HTH_Tnp_1_2 PF13022.6 EGF81096.1 - 0.0056 16.8 5.0 0.59 10.3 1.3 2.3 1 1 1 2 2 2 2 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 EGF81096.1 - 0.021 14.8 1.8 2.6 8.1 0.1 3.0 3 1 0 3 3 3 0 Winged helix-turn helix DUF1804 PF08822.11 EGF81096.1 - 0.098 12.6 5.3 0.15 12.1 4.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) HTH_psq PF05225.16 EGF81096.1 - 0.21 11.4 1.8 0.65 9.8 0.1 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.20 EGF81096.1 - 0.56 10.5 9.5 0.063 13.6 3.4 2.2 2 1 1 3 3 3 0 Transposase HTH_8 PF02954.19 EGF81096.1 - 8.5 6.3 7.5 23 4.9 0.1 3.5 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family Enolase_C PF00113.22 EGF81098.1 - 9.3e-157 520.8 0.0 1.3e-156 520.4 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGF81098.1 - 3.2e-57 192.3 0.4 5.1e-57 191.7 0.4 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGF81098.1 - 2.7e-11 43.4 0.0 6.7e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGF81098.1 - 0.002 17.4 0.6 0.004 16.3 0.1 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus p450 PF00067.22 EGF81099.1 - 5.1e-44 150.8 0.0 6.8e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Urocanase_N PF17391.2 EGF81099.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Urocanase N-terminal domain CRT10 PF08728.10 EGF81101.1 - 1.1e-09 37.1 1.9 4.8e-08 31.7 0.6 2.7 2 1 0 2 2 2 2 CRT10 WD40 PF00400.32 EGF81101.1 - 6.4e-08 33.1 4.6 4.4e-06 27.3 0.3 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81101.1 - 0.12 12.7 0.2 5.7 7.3 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SH3_1 PF00018.28 EGF81102.1 - 2.6e-42 142.2 3.0 9.6e-15 53.9 0.0 4.5 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 EGF81102.1 - 8.2e-37 124.8 5.9 1.7e-13 50.2 0.1 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 EGF81102.1 - 6.9e-34 115.3 0.2 3.3e-12 45.9 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain FCH PF00611.23 EGF81102.1 - 3.1e-09 37.0 1.8 1.6e-08 34.7 0.2 2.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3104 PF11302.8 EGF81102.1 - 0.0045 16.7 2.3 8.9 6.1 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3104) ADK PF00406.22 EGF81103.1 - 6.7e-42 143.1 2.5 1.2e-11 44.9 0.0 5.9 4 2 0 4 4 4 4 Adenylate kinase AAA_17 PF13207.6 EGF81103.1 - 3.4e-27 95.5 0.0 2.1e-09 37.9 0.0 5.6 4 1 0 4 4 4 4 AAA domain AAA_18 PF13238.6 EGF81103.1 - 7.6e-18 65.3 1.8 0.00095 19.7 0.0 5.5 6 1 0 6 6 5 4 AAA domain FAP206 PF12018.8 EGF81103.1 - 1e-14 54.7 0.9 2.8e-05 23.8 0.1 4.7 4 0 0 4 4 4 3 Domain of unknown function YHS PF04945.13 EGF81103.1 - 6e-12 45.5 4.1 0.0019 18.2 0.0 4.5 4 0 0 4 4 4 3 YHS domain AAA_28 PF13521.6 EGF81103.1 - 1.2e-10 41.9 0.2 0.1 12.8 0.0 4.6 4 0 0 4 4 4 3 AAA domain AAA_33 PF13671.6 EGF81103.1 - 1.2e-10 41.7 0.0 0.08 13.1 0.0 5.0 5 0 0 5 5 5 3 AAA domain AAA PF00004.29 EGF81103.1 - 1.5e-09 38.3 0.1 0.078 13.4 0.0 4.4 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 EGF81103.1 - 1.4e-06 28.8 0.5 0.33 11.2 0.0 4.8 4 1 0 4 4 4 2 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 EGF81103.1 - 3.2e-06 27.5 0.1 4.4 7.6 0.0 5.3 5 0 0 5 5 5 2 AAA domain NACHT PF05729.12 EGF81103.1 - 4.5e-06 26.7 0.1 0.00071 19.5 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 EGF81103.1 - 7.1e-06 25.9 0.0 1.1 9.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain KTI12 PF08433.10 EGF81103.1 - 1.1e-05 25.1 0.1 1.7 8.0 0.0 4.1 4 0 0 4 4 4 2 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EGF81103.1 - 0.00014 22.2 0.1 13 6.2 0.0 5.2 5 0 0 5 5 4 0 RNA helicase Cytidylate_kin PF02224.18 EGF81103.1 - 0.00025 20.9 0.1 7.4 6.2 0.0 4.0 4 0 0 4 4 3 0 Cytidylate kinase SKI PF01202.22 EGF81103.1 - 0.00099 19.3 0.1 7.7 6.6 0.0 4.7 4 0 0 4 4 4 0 Shikimate kinase SRPRB PF09439.10 EGF81103.1 - 0.0016 17.9 0.1 22 4.4 0.0 4.7 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EGF81103.1 - 0.0044 17.0 0.3 39 4.3 0.0 4.9 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 EGF81103.1 - 0.0048 17.3 0.0 2.2 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 EGF81103.1 - 0.0053 16.0 0.0 4 6.6 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGF81103.1 - 0.011 16.2 0.0 2.7 8.3 0.0 3.8 5 0 0 5 5 3 0 AAA ATPase domain AAA_7 PF12775.7 EGF81103.1 - 0.028 13.9 0.0 0.72 9.3 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_29 PF13555.6 EGF81103.1 - 0.029 14.1 0.2 2.8 7.7 0.0 3.6 4 0 0 4 4 3 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGF81103.1 - 0.03 14.8 0.7 2.7 8.5 0.0 3.6 4 1 0 4 4 2 0 ABC transporter PduV-EutP PF10662.9 EGF81103.1 - 0.034 13.9 0.1 5.8 6.7 0.0 3.6 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EGF81103.1 - 0.034 14.1 0.0 0.81 9.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EGF81103.1 - 0.048 13.0 0.0 30 3.9 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI CobU PF02283.16 EGF81103.1 - 0.074 12.6 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_30 PF13604.6 EGF81103.1 - 0.098 12.4 0.0 0.65 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EGF81103.1 - 0.11 12.3 0.0 2 8.2 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EGF81103.1 - 3.5 8.1 0.0 3.5 8.1 0.0 4.4 7 0 0 7 7 3 0 AAA domain Cyclin PF08613.11 EGF81104.1 - 2.7e-05 24.6 1.5 8.7e-05 22.9 1.5 2.1 1 1 0 1 1 1 1 Cyclin Acetyltransf_16 PF05301.11 EGF81105.1 - 4.3e-48 163.4 4.0 2.9e-36 124.9 1.5 2.7 2 1 0 2 2 2 2 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 EGF81105.1 - 0.028 14.9 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 2-oxoacid_dh PF00198.23 EGF81106.1 - 2.4e-68 230.1 0.9 3.4e-68 229.6 0.1 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGF81106.1 - 2.4e-18 65.7 0.0 5.5e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGF81106.1 - 1.2e-15 57.5 0.3 1.2e-15 57.5 0.3 1.8 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGF81106.1 - 0.021 14.7 0.7 1 9.3 0.1 3.5 3 0 0 3 3 3 0 Biotin-lipoyl like DUF5077 PF16871.5 EGF81106.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) SMAP PF15477.6 EGF81107.1 - 1.7e-10 41.7 0.4 1.7e-10 41.7 0.4 3.6 2 1 0 2 2 2 1 Small acidic protein family zf-RING_2 PF13639.6 EGF81108.1 - 7.6e-09 35.8 12.7 7.6e-09 35.8 12.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGF81108.1 - 1.2e-08 34.8 12.1 1.2e-08 34.8 12.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGF81108.1 - 1.6e-08 34.6 14.6 1.6e-08 34.6 14.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGF81108.1 - 9.1e-08 31.9 14.2 9.1e-08 31.9 14.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF81108.1 - 3e-06 27.0 10.3 3e-06 27.0 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF81108.1 - 6.1e-06 26.0 13.4 6.1e-06 26.0 13.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF81108.1 - 9.8e-05 22.2 13.0 9.8e-05 22.2 13.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGF81108.1 - 0.00036 20.5 3.5 0.00036 20.5 3.5 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGF81108.1 - 0.002 18.4 9.4 0.002 18.4 9.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-Mss51 PF13824.6 EGF81108.1 - 0.071 13.2 0.3 0.071 13.2 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Mu-like_Com PF10122.9 EGF81108.1 - 1.6 8.2 6.0 1.1 8.8 2.6 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_4 PF13717.6 EGF81108.1 - 2.2 8.3 7.3 1.8 8.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_4 PF14447.6 EGF81108.1 - 3.4 7.6 15.1 0.64 9.9 10.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGF81108.1 - 3.7 7.7 14.7 0.75 10.0 9.4 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Mago_nashi PF02792.14 EGF81109.1 - 5.9e-78 259.9 0.3 6.6e-78 259.7 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.8 EGF81109.1 - 0.028 14.4 0.1 0.05 13.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) UQ_con PF00179.26 EGF81110.1 - 3.2e-39 133.8 0.0 4.1e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGF81110.1 - 0.0047 16.6 0.1 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EGF81110.1 - 0.16 12.3 0.2 0.23 11.8 0.2 1.5 1 1 0 1 1 1 0 RWD domain Band_7 PF01145.25 EGF81111.1 - 4.1e-20 72.5 0.3 5.8e-20 72.0 0.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Viral_P18 PF04521.13 EGF81111.1 - 0.053 13.3 0.1 0.64 9.8 0.1 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein LRR_6 PF13516.6 EGF81112.1 - 2e-21 74.2 14.5 5.5e-06 26.0 0.1 8.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 EGF81112.1 - 1.1e-06 28.3 0.1 5.4 8.0 0.0 5.5 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 EGF81112.1 - 3e-05 24.3 4.5 0.056 13.9 0.0 3.9 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF81112.1 - 0.001 18.8 5.4 0.075 12.8 0.3 4.0 2 2 1 3 3 3 3 Leucine rich repeat Mg_trans_NIPA PF05653.14 EGF81113.1 - 2e-27 96.1 10.0 1.3e-23 83.5 3.4 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGF81113.1 - 0.0019 18.3 2.1 0.0019 18.3 2.1 3.6 3 1 0 3 3 3 1 EamA-like transporter family Ribosomal_S30 PF04758.14 EGF81115.1 - 5.2e-29 100.2 9.5 6.3e-29 100.0 9.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 MDM31_MDM32 PF08118.11 EGF81116.1 - 8.4e-128 427.3 0.0 1.3e-127 426.7 0.0 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins FOP_dimer PF09398.10 EGF81117.1 - 1.5e-14 54.0 0.0 3.1e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 EGF81117.1 - 1.1e-05 24.4 0.0 2.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 LisH PhoLip_ATPase_C PF16212.5 EGF81118.1 - 1.3e-64 218.3 25.8 1.3e-64 218.3 25.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGF81118.1 - 3.2e-18 65.2 0.3 1.3e-17 63.2 0.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGF81118.1 - 2.8e-11 44.1 0.2 0.001 19.4 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGF81118.1 - 7.9e-11 41.8 0.2 7.9e-11 41.8 0.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGF81118.1 - 1.5e-09 37.8 0.0 5.3e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGF81118.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 EGF81118.1 - 0.7 10.0 11.9 0.072 13.2 2.2 3.0 2 0 0 2 2 2 0 C-terminus of AA_permease Maf PF02545.14 EGF81119.1 - 7.4e-33 113.7 0.0 8.3e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NDT80_PhoG PF05224.12 EGF81120.1 - 4.8e-28 98.6 0.0 1.2e-27 97.4 0.0 1.7 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Las1 PF04031.13 EGF81121.1 - 4.8e-48 163.2 0.1 9.7e-48 162.2 0.1 1.5 1 0 0 1 1 1 1 Las1-like HECT PF00632.25 EGF81122.1 - 6.7e-90 301.7 0.0 7.4e-90 301.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PIG-U PF06728.13 EGF81123.1 - 8.7e-101 337.7 35.1 1e-100 337.5 35.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EGF81123.1 - 0.18 11.4 27.0 0.0079 15.9 20.5 1.9 2 1 0 2 2 2 0 8TM Microsporidial transmembrane domain WD40 PF00400.32 EGF81124.1 - 0.00022 22.0 5.1 0.0069 17.2 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81124.1 - 0.00025 21.3 0.1 0.96 9.8 0.0 3.7 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 EGF81125.1 - 9.4e-41 139.5 0.9 2.1e-40 138.3 0.7 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF81125.1 - 4.6e-30 104.2 0.2 2.6e-29 101.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF81125.1 - 2.7e-11 43.8 0.0 1.9e-09 37.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NUFIP2 PF15293.6 EGF81125.1 - 0.0043 16.0 0.2 0.016 14.1 0.0 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 2 DUF3802 PF12290.8 EGF81125.1 - 0.069 13.7 0.2 26 5.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) UBX PF00789.20 EGF81126.1 - 5.3e-17 61.8 0.0 1e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.14 EGF81126.1 - 0.024 13.9 1.8 0.032 13.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3541 PF12060.8 EGF81126.1 - 0.098 12.3 3.1 0.21 11.2 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3541) Dus PF01207.17 EGF81127.1 - 9.9e-48 162.8 0.0 9.7e-40 136.6 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EGF81127.1 - 2.4e-10 39.9 10.6 2.4e-05 24.0 0.6 2.7 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 EGF81127.1 - 2.4e-08 33.6 8.5 0.00035 20.4 0.1 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGF81127.1 - 9.3e-05 22.3 9.6 0.0098 15.9 0.8 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGF81127.1 - 0.018 15.7 1.2 0.018 15.7 1.2 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 EGF81127.1 - 0.68 10.5 7.5 3.9 8.1 1.2 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger SH3_1 PF00018.28 EGF81128.1 - 4.8e-12 45.3 0.1 1e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGF81128.1 - 2.2e-09 37.0 0.0 3.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF81128.1 - 2.9e-06 26.8 0.1 9.1e-06 25.3 0.1 1.8 1 1 1 2 2 2 1 Variant SH3 domain DKCLD PF08068.12 EGF81129.1 - 1.1e-33 115.1 1.4 3.6e-32 110.2 0.2 3.1 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EGF81129.1 - 1.3e-23 82.9 0.7 3.2e-23 81.7 0.7 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGF81129.1 - 1.8e-23 83.6 0.3 2.1e-20 73.6 0.3 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGF81129.1 - 1.2e-20 73.2 1.1 2.4e-20 72.2 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EGF81129.1 - 0.0033 17.7 0.0 0.009 16.3 0.0 1.8 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 EGF81129.1 - 6.8 6.7 30.2 11 6.0 30.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Asp PF00026.23 EGF81130.1 - 3.6e-112 374.9 0.1 5.2e-112 374.3 0.0 1.3 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGF81130.1 - 2e-15 57.5 0.7 8.7e-09 35.9 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGF81130.1 - 3.2e-05 23.8 0.0 0.0007 19.4 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EGF81130.1 - 0.00048 20.7 0.6 0.49 11.1 0.0 3.5 3 1 0 3 3 3 2 Aspartyl protease Pkinase PF00069.25 EGF81131.1 - 4.7e-73 245.8 0.0 5.3e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81131.1 - 2.2e-37 128.7 0.0 9.7e-36 123.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF81131.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 EGF81132.1 - 2.7e-49 167.9 0.0 5.2e-38 130.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGF81132.1 - 5.3e-17 62.6 0.0 9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fzo_mitofusin PF04799.13 EGF81132.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Flavodoxin_1 PF00258.25 EGF81132.1 - 0.059 13.6 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin Pox_A_type_inc PF04508.12 EGF81132.1 - 0.12 12.3 5.1 4.1 7.4 0.0 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Sel1 PF08238.12 EGF81133.1 - 7.8e-47 156.7 14.9 1.1e-10 41.8 0.0 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 EGF81133.1 - 3.4e-05 24.2 3.9 2.2 9.1 0.4 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81133.1 - 0.013 16.3 9.6 0.66 11.0 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_5 PF12688.7 EGF81133.1 - 0.074 13.3 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_1 PF00515.28 EGF81133.1 - 0.23 11.3 3.8 1.7 8.6 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81133.1 - 1.1 9.7 5.1 9.3 6.8 0.0 4.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TFCD_C PF12612.8 EGF81134.1 - 1.7e-49 168.3 1.2 2e-48 164.7 0.4 2.7 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGF81134.1 - 2.6e-05 24.1 14.4 0.52 10.7 0.0 8.7 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 EGF81134.1 - 3.3e-05 24.2 6.2 1.4 9.4 0.0 5.6 6 0 0 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF81134.1 - 0.0052 17.4 0.0 15 6.2 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Acyltransferase PF01553.21 EGF81135.1 - 2.5e-22 78.9 0.0 4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGF81135.1 - 1.9e-10 40.7 0.1 1.1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase C-terminus ATP-grasp_2 PF08442.10 EGF81136.1 - 2.7e-73 245.8 0.5 4.6e-73 245.1 0.5 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGF81136.1 - 6.7e-26 90.9 0.4 1.3e-25 90.1 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGF81136.1 - 1.2e-05 24.9 0.2 2.3e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGF81136.1 - 0.014 15.2 0.1 0.026 14.3 0.1 1.5 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 EGF81136.1 - 0.03 14.6 0.3 0.07 13.4 0.1 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pkinase PF00069.25 EGF81137.1 - 9.9e-47 159.5 0.0 2.5e-46 158.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81137.1 - 4e-26 91.8 0.0 8.5e-26 90.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF81137.1 - 2e-05 24.6 0.7 2.4e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF81137.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DMA PF03474.14 EGF81137.1 - 0.1 12.2 0.0 0.6 9.8 0.1 2.0 2 0 0 2 2 2 0 DMRTA motif MBOAT PF03062.19 EGF81138.1 - 3e-29 102.5 11.7 8.8e-29 100.9 11.7 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MAPEG PF01124.18 EGF81139.1 - 1.7e-21 76.5 0.7 2e-21 76.2 0.7 1.1 1 0 0 1 1 1 1 MAPEG family Acyl_transf_3 PF01757.22 EGF81140.1 - 1.1e-21 77.4 36.4 1.4e-21 76.9 36.4 1.2 1 0 0 1 1 1 1 Acyltransferase family bZIP_1 PF00170.21 EGF81141.1 - 5e-08 32.9 17.8 1.5e-06 28.2 7.1 2.8 3 1 0 3 3 3 2 bZIP transcription factor GIT_CC PF16559.5 EGF81141.1 - 0.00079 19.2 5.9 0.0021 17.9 5.9 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 EGF81141.1 - 0.013 15.6 6.4 0.013 15.6 6.4 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 EGF81141.1 - 0.71 10.0 19.4 0.32 11.1 7.1 2.8 2 1 1 3 3 3 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 EGF81141.1 - 0.75 10.4 11.4 3.5 8.2 0.0 3.1 2 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF349 PF03993.12 EGF81141.1 - 1.5 9.2 8.7 1.1 9.6 1.7 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) V_ATPase_I PF01496.19 EGF81141.1 - 2.2 6.1 6.8 3.1 5.6 6.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 EGF81141.1 - 2.5 7.3 13.9 0.6 9.4 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 EGF81142.1 - 1.7e-33 116.1 0.0 2.2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81142.1 - 1.3e-16 60.7 0.0 1.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81142.1 - 2.1e-07 30.6 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF81142.1 - 0.00098 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF81142.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGF81142.1 - 0.041 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EGF81142.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EGF81142.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Chitin_synth_2 PF03142.15 EGF81143.1 - 8.9e-213 707.7 0.6 1e-212 707.5 0.6 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGF81143.1 - 2.9e-14 53.5 4.9 7.8e-14 52.0 4.9 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF81143.1 - 7.6e-11 42.3 0.0 1.8e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF81143.1 - 4.4e-08 32.8 0.1 8e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF81143.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF1418 PF07214.12 EGF81143.1 - 3 7.8 5.1 8.7 6.3 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) VHS PF00790.19 EGF81144.1 - 1.1e-40 138.7 0.3 1.1e-40 138.7 0.3 2.6 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 EGF81144.1 - 2.1e-17 63.0 9.6 4e-17 62.1 9.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EGF81144.1 - 1.6e-07 30.7 2.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EGF81144.1 - 8.9e-05 22.7 3.1 0.00051 20.3 1.4 2.5 2 0 0 2 2 2 1 GAT domain FYVE_2 PF02318.16 EGF81144.1 - 0.00025 21.2 5.3 0.00068 19.8 5.3 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger AbiEi_3 PF11459.8 EGF81144.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system DZR PF12773.7 EGF81144.1 - 0.17 12.0 10.0 45 4.2 10.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon TruD PF01142.18 EGF81145.1 - 1.4e-70 238.3 0.0 6.1e-69 232.8 0.0 2.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Trypan_PARP PF05887.11 EGF81145.1 - 0.025 14.6 13.9 0.048 13.6 13.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cpn60_TCP1 PF00118.24 EGF81146.1 - 0.0016 17.2 0.1 0.0042 15.8 0.0 1.7 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family PDZ_1 PF12812.7 EGF81147.1 - 1.5e-41 140.2 0.0 2.5e-27 94.7 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EGF81147.1 - 7.4e-23 82.1 0.2 5.5e-19 69.5 0.0 2.9 3 0 0 3 3 3 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 EGF81147.1 - 2.2e-13 49.8 0.7 2.9e-06 27.0 0.2 3.4 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 EGF81147.1 - 7.5e-10 39.0 1.9 6e-05 23.3 0.2 4.2 4 0 0 4 4 4 2 PDZ domain Trypsin PF00089.26 EGF81147.1 - 0.00021 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 EGF81147.1 - 0.00039 19.2 0.4 0.0013 17.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase S46 PDZ PF00595.24 EGF81147.1 - 0.0015 18.9 0.0 0.18 12.2 0.1 3.3 4 0 0 4 4 4 1 PDZ domain Peptidase_S7 PF00949.21 EGF81147.1 - 0.0078 16.0 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.6 EGF81147.1 - 0.0094 15.9 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF31 PF01732.16 EGF81147.1 - 0.1 12.1 0.7 0.15 11.6 0.7 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Acyltransferase PF01553.21 EGF81148.1 - 0.15 11.7 0.0 0.64 9.6 0.0 2.0 2 0 0 2 2 2 0 Acyltransferase Peptidase_M48 PF01435.18 EGF81149.1 - 6.1e-37 127.3 0.0 9.1e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 EGF81149.1 - 0.075 12.6 0.4 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Kelch_2 PF07646.15 EGF81149.1 - 0.19 11.8 0.1 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif TCTP PF00838.17 EGF81151.1 - 2e-70 236.5 5.2 2.2e-70 236.3 5.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Acyltransferase PF01553.21 EGF81153.1 - 0.13 11.8 0.0 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 Acyltransferase LSM PF01423.22 EGF81154.1 - 6.8e-16 57.7 0.0 8.1e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF81154.1 - 0.13 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S14 PF00253.21 EGF81155.1 - 4.9e-15 55.0 2.0 5.8e-15 54.8 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 EGF81155.1 - 0.026 14.4 0.4 0.036 14.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Syntaxin-6_N PF09177.11 EGF81156.1 - 1.1e-25 90.0 2.7 1.1e-25 90.0 2.7 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EGF81156.1 - 2.6e-09 36.9 0.8 2.6e-09 36.9 0.8 1.9 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 EGF81156.1 - 3.1e-05 23.8 7.0 4.2e-05 23.4 7.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 CHASE3 PF05227.13 EGF81156.1 - 0.0025 17.7 0.5 0.0025 17.7 0.5 2.4 2 1 0 2 2 2 1 CHASE3 domain T2SSF PF00482.23 EGF81156.1 - 0.017 15.0 1.2 0.36 10.8 0.4 2.6 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F NPV_P10 PF05531.12 EGF81156.1 - 0.031 14.7 6.8 1.3 9.6 0.3 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 EGF81156.1 - 0.04 13.0 6.9 0.052 12.6 6.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 EGF81156.1 - 0.066 12.9 8.7 0.2 11.3 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Cortex-I_coil PF09304.10 EGF81156.1 - 0.18 12.0 11.3 5.8 7.2 0.1 3.8 1 1 3 4 4 4 0 Cortexillin I, coiled coil FAM76 PF16046.5 EGF81156.1 - 0.59 9.4 8.3 0.74 9.1 8.3 1.2 1 0 0 1 1 1 0 FAM76 protein HemX PF04375.14 EGF81156.1 - 3 7.1 13.4 2.2 7.5 0.7 2.1 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATG16 PF08614.11 EGF81156.1 - 3.3 7.9 13.1 0.25 11.6 0.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TBCA PF02970.16 EGF81156.1 - 4.8 7.6 12.8 3.5 8.0 3.0 3.4 2 2 1 3 3 3 0 Tubulin binding cofactor A TipAS PF07739.13 EGF81156.1 - 5.1 7.7 7.4 3 8.4 3.4 2.6 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain BST2 PF16716.5 EGF81156.1 - 6.9 7.3 9.7 3.1 8.5 2.4 2.6 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 ATP-synt_F PF01990.17 EGF81157.1 - 3.8e-33 113.7 0.2 4.5e-33 113.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 EGF81157.1 - 0.014 15.3 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 PIN like domain RRN3 PF05327.11 EGF81158.1 - 1.1e-137 460.0 5.1 1.2e-137 459.8 5.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Dynamin_N PF00350.23 EGF81159.1 - 7.1e-46 156.3 0.0 1.5e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGF81159.1 - 6.8e-16 58.3 0.1 6.8e-16 58.3 0.1 2.7 2 1 1 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 EGF81159.1 - 5e-06 26.6 0.0 6.3e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF81159.1 - 0.0063 16.4 0.2 4.7 7.1 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase MHB PF16525.5 EGF81159.1 - 0.01 16.1 0.9 3.3 8.0 0.0 3.3 3 0 0 3 3 2 1 Haemophore, haem-binding ABC_tran PF00005.27 EGF81159.1 - 0.015 15.9 0.7 10 6.7 0.0 3.2 3 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 EGF81159.1 - 0.026 14.3 0.4 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Tnp_DNA_bind PF14706.6 EGF81159.1 - 0.041 13.8 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Transposase DNA-binding Se-cys_synth_N PF12390.8 EGF81159.1 - 0.085 13.1 0.0 2.1 8.6 0.0 2.9 2 0 0 2 2 2 0 Selenocysteine synthase N terminal PduV-EutP PF10662.9 EGF81159.1 - 0.092 12.5 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Colicin PF01024.19 EGF81159.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Colicin pore forming domain AAA_16 PF13191.6 EGF81159.1 - 0.096 13.1 3.9 0.19 12.1 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EGF81159.1 - 0.099 12.9 0.6 0.78 10.0 0.0 2.8 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EGF81159.1 - 0.47 10.1 2.6 0.58 9.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain MscS_porin PF12795.7 EGF81159.1 - 3.5 7.1 12.9 3.1 7.3 4.5 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CBS PF00571.28 EGF81160.1 - 1.4e-26 92.7 5.5 2.4e-06 27.9 0.1 4.5 4 0 0 4 4 4 4 CBS domain DUF2733 PF10813.8 EGF81160.1 - 0.029 14.1 0.1 0.09 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) UCR_hinge PF02320.16 EGF81161.1 - 8.1e-17 61.2 1.4 1.6e-16 60.3 1.4 1.5 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DEAD PF00270.29 EGF81162.1 - 2.6e-49 167.4 0.0 4.5e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF81162.1 - 2e-31 108.6 0.0 1.3e-28 99.5 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGF81162.1 - 0.00089 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PBP PF01161.20 EGF81163.1 - 1.2e-14 54.8 0.1 2.1e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Chs7 PF12271.8 EGF81164.1 - 1.2e-107 359.6 20.9 1.4e-107 359.4 20.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ferric_reduct PF01794.19 EGF81165.1 - 3.5e-14 53.0 13.4 3.5e-14 53.0 13.4 3.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGF81165.1 - 2e-11 44.3 0.1 3.3e-10 40.3 0.1 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGF81165.1 - 6.6e-10 39.1 0.3 2.2e-09 37.3 0.1 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EGF81165.1 - 0.00088 19.9 0.0 0.0037 17.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FliH PF02108.16 EGF81165.1 - 0.061 13.4 0.0 0.095 12.8 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH TFIIF_alpha PF05793.12 EGF81167.1 - 3.4 6.1 38.6 4.3 5.8 38.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hamartin PF04388.12 EGF81167.1 - 3.4 6.2 26.0 4.8 5.7 26.0 1.3 1 0 0 1 1 1 0 Hamartin protein Acyl-CoA_dh_1 PF00441.24 EGF81168.1 - 4.5e-48 163.3 1.2 6.4e-48 162.8 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF81168.1 - 5.8e-26 90.5 0.0 1.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGF81168.1 - 5.3e-25 88.3 0.0 1.1e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF81168.1 - 2.7e-20 73.0 0.1 5.1e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGF81169.1 - 8.9e-41 139.7 0.8 1.3e-40 139.2 0.8 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGF81169.1 - 3.6e-30 104.7 0.0 7.6e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGF81169.1 - 0.00044 20.8 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EGF81169.1 - 0.0033 16.4 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family WD40 PF00400.32 EGF81171.1 - 7e-28 96.3 17.9 1.7e-07 31.8 0.1 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81171.1 - 0.00019 21.6 0.6 0.43 10.9 0.2 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF81171.1 - 0.00098 18.2 0.0 7.5 5.4 0.0 3.2 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein YchF-GTPase_C PF06071.13 EGF81172.1 - 5.2e-34 116.3 0.2 5.2e-34 116.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGF81172.1 - 7.2e-22 77.6 0.0 1.7e-21 76.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF81172.1 - 1.2e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EGF81172.1 - 0.0087 16.6 0.0 1.8 9.1 0.0 2.9 3 1 0 3 3 3 1 ABC transporter TGS PF02824.21 EGF81172.1 - 0.011 15.7 0.2 0.033 14.3 0.0 1.9 2 0 0 2 2 2 0 TGS domain SHD1 PF03983.12 EGF81172.1 - 0.036 13.9 0.2 9.5 6.1 0.0 3.1 3 0 0 3 3 3 0 SLA1 homology domain 1, SHD1 RsgA_GTPase PF03193.16 EGF81172.1 - 0.16 11.9 0.0 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase zf-H2C2_2 PF13465.6 EGF81173.1 - 0.53 10.8 12.2 0.13 12.7 4.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Ank_2 PF12796.7 EGF81175.1 - 3.9e-11 43.4 11.1 0.00096 19.7 0.1 5.5 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF81175.1 - 1.6e-08 34.6 5.6 0.1 13.0 0.1 6.6 3 1 4 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGF81175.1 - 2.2e-08 34.4 12.0 0.01 16.4 0.5 6.3 4 3 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF81175.1 - 0.28 11.9 6.8 1e+02 4.0 0.0 6.3 7 0 0 7 7 7 0 Ankyrin repeat Ank PF00023.30 EGF81175.1 - 9.1 6.9 9.1 1.4e+02 3.2 0.2 5.5 3 3 0 3 3 3 0 Ankyrin repeat Proteasome PF00227.26 EGF81176.1 - 6.6e-61 205.1 0.1 8.5e-61 204.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF81176.1 - 4.9e-09 35.7 0.2 1.6e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_M2 PF01401.18 EGF81177.1 - 0.069 11.8 5.3 0.089 11.4 5.3 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF3128 PF11326.8 EGF81177.1 - 2.3 8.7 6.8 7.2 7.1 6.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) IGPD PF00475.18 EGF81178.1 - 3.8e-57 192.6 0.4 5.3e-57 192.2 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase NUDIX PF00293.28 EGF81180.1 - 7e-12 45.5 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GDPD PF03009.17 EGF81181.1 - 1.2e-21 77.6 0.0 9.1e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGF81181.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GIY-YIG PF01541.24 EGF81182.1 - 9.4e-13 48.3 0.0 1.7e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EGF81182.1 - 8.9e-06 25.8 8.4 1.7e-05 24.9 8.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EGF81182.1 - 0.022 15.1 11.9 1.6 9.1 11.9 2.7 1 1 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 EGF81182.1 - 0.056 13.7 2.7 0.12 12.7 2.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGF81182.1 - 0.062 13.5 2.3 0.14 12.4 2.3 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.22 EGF81182.1 - 4.3 7.3 6.4 4.2 7.3 4.2 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SAC3_GANP PF03399.16 EGF81184.1 - 8.8e-22 77.8 3.3 8.2e-20 71.4 3.3 2.0 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGF81184.1 - 0.0022 18.0 0.1 0.0085 16.1 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Peptidase_M36 PF02128.15 EGF81186.1 - 1.2e-135 452.4 0.5 1.2e-135 452.4 0.5 1.6 2 0 0 2 2 2 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF81186.1 - 1.5e-10 40.8 0.9 3.4e-10 39.6 0.8 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EGF81186.1 - 0.013 16.0 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Peptidase_M4_C PF02868.15 EGF81186.1 - 0.024 14.5 0.4 0.2 11.5 0.1 2.4 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Nucleopor_Nup85 PF07575.13 EGF81187.1 - 4.1e-39 134.6 0.2 4.8e-39 134.4 0.2 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.14 EGF81187.1 - 0.084 11.3 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 PDCD2_C PF04194.13 EGF81188.1 - 3.6e-37 128.1 1.4 5.8e-35 120.9 0.4 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 EGF81188.1 - 9.1e-08 32.1 9.2 9.1e-08 32.1 9.2 3.7 4 0 0 4 4 4 1 MYND finger zinc_ribbon_4 PF13717.6 EGF81188.1 - 3.5 7.6 8.5 17 5.4 0.5 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Filament PF00038.21 EGF81189.1 - 8.6e-05 22.3 2.5 8.6e-05 22.3 2.5 1.4 1 1 0 1 1 1 1 Intermediate filament protein Baculo_PEP_C PF04513.12 EGF81189.1 - 0.00043 20.3 4.8 0.088 12.8 0.0 2.8 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 EGF81189.1 - 0.0006 18.9 9.5 0.0031 16.6 5.1 2.0 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 MscS_porin PF12795.7 EGF81189.1 - 0.0067 16.0 2.7 0.01 15.4 1.6 1.8 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF4810 PF16068.5 EGF81189.1 - 0.0081 16.7 0.3 0.16 12.5 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4810) DUF2730 PF10805.8 EGF81189.1 - 0.01 15.9 5.2 1 9.5 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 EGF81189.1 - 0.011 15.8 10.5 1.5 8.9 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EGF81189.1 - 0.013 14.6 7.9 0.018 14.1 7.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EGF81189.1 - 0.015 15.6 2.3 0.015 15.6 2.3 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EGF81189.1 - 0.017 14.0 10.7 0.038 12.9 9.8 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein CREPT PF16566.5 EGF81189.1 - 0.018 15.2 2.6 0.018 15.2 2.6 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour V-SNARE PF05008.15 EGF81189.1 - 0.02 15.2 3.5 0.02 15.2 3.5 2.0 2 1 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus Apolipoprotein PF01442.18 EGF81189.1 - 0.028 14.3 4.9 0.71 9.7 0.0 2.5 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain SseC PF04888.12 EGF81189.1 - 0.037 13.6 9.2 0.048 13.3 7.1 2.0 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family CdvA PF18822.1 EGF81189.1 - 0.041 13.7 12.5 0.42 10.5 0.1 3.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Senescence PF06911.12 EGF81189.1 - 0.045 14.1 3.2 0.081 13.2 3.2 1.6 1 1 0 1 1 1 0 Senescence-associated protein Uso1_p115_C PF04871.13 EGF81189.1 - 0.046 14.1 11.5 0.042 14.2 8.0 2.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 EGF81189.1 - 0.059 13.8 8.1 0.81 10.1 3.4 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.17 EGF81189.1 - 0.066 13.1 8.6 0.59 10.1 3.3 2.9 3 0 0 3 3 3 0 Prefoldin subunit DUF5082 PF16888.5 EGF81189.1 - 0.072 13.4 9.1 3 8.1 0.0 3.0 1 1 2 3 3 2 0 Domain of unknown function (DUF5082) DUF5446 PF17522.2 EGF81189.1 - 0.084 13.0 2.2 0.31 11.2 1.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Cluap1 PF10234.9 EGF81189.1 - 0.088 12.2 9.5 0.39 10.1 6.4 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 DivIC PF04977.15 EGF81189.1 - 0.089 12.6 4.8 0.11 12.3 2.9 2.2 2 0 0 2 2 1 0 Septum formation initiator DUF16 PF01519.16 EGF81189.1 - 0.1 13.1 9.3 0.32 11.5 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Erf4 PF10256.9 EGF81189.1 - 0.14 12.3 0.6 1.1 9.3 0.1 2.5 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family ATG16 PF08614.11 EGF81189.1 - 0.17 12.1 10.7 2.2 8.5 9.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EGF81189.1 - 0.18 12.4 3.6 3 8.5 0.4 3.4 3 1 0 3 3 3 0 SlyX DUF641 PF04859.12 EGF81189.1 - 0.21 11.9 6.9 0.26 11.6 3.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.6 EGF81189.1 - 0.22 10.1 9.5 0.5 8.9 9.5 1.7 1 1 0 1 1 1 0 AAA domain COG5 PF10392.9 EGF81189.1 - 0.27 11.4 7.8 2.7 8.2 0.8 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 AAA_lid_9 PF17871.1 EGF81189.1 - 0.32 10.9 5.9 3.3 7.7 2.4 2.7 1 1 1 3 3 3 0 AAA lid domain KxDL PF10241.9 EGF81189.1 - 0.33 11.2 8.0 9.9 6.5 2.8 3.2 2 1 2 4 4 4 0 Uncharacterized conserved protein APG6_N PF17675.1 EGF81189.1 - 0.42 11.1 7.7 0.75 10.3 6.9 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 EGF81189.1 - 0.47 10.5 8.5 0.75 9.9 8.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 EGF81189.1 - 0.49 10.5 8.8 4.1 7.5 0.0 2.6 2 1 1 3 3 2 0 Designed helical repeat protein 10 domain Dynactin_p22 PF07426.11 EGF81189.1 - 0.5 10.2 10.2 2.7 7.8 7.8 2.8 2 1 0 2 2 2 0 Dynactin subunit p22 DUF4446 PF14584.6 EGF81189.1 - 0.62 10.0 4.5 6.1 6.8 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) KASH_CCD PF14662.6 EGF81189.1 - 0.63 9.8 10.9 1.1 9.0 10.8 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 EGF81189.1 - 0.64 10.2 9.8 0.94 9.7 6.9 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 EGF81189.1 - 0.65 10.2 4.0 21 5.3 0.0 3.4 3 2 0 3 3 3 0 MbeD/MobD like BLOC1_2 PF10046.9 EGF81189.1 - 0.83 10.0 7.6 1.4 9.2 2.6 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LapA_dom PF06305.11 EGF81189.1 - 0.93 9.4 9.8 2.9 7.8 1.0 2.9 3 0 0 3 3 2 0 Lipopolysaccharide assembly protein A domain ABC_tran_CTD PF16326.5 EGF81189.1 - 0.94 9.8 8.5 61 4.0 7.1 3.4 2 1 0 2 2 1 0 ABC transporter C-terminal domain BST2 PF16716.5 EGF81189.1 - 1 10.0 10.1 0.23 12.1 5.2 2.3 2 1 0 3 3 2 0 Bone marrow stromal antigen 2 TBCA PF02970.16 EGF81189.1 - 1.6 9.1 8.7 1.2 9.5 4.3 2.7 1 1 2 3 3 3 0 Tubulin binding cofactor A Fzo_mitofusin PF04799.13 EGF81189.1 - 1.9 8.0 9.1 1 8.9 0.4 2.6 1 1 1 3 3 3 0 fzo-like conserved region DUF4200 PF13863.6 EGF81189.1 - 2 8.9 11.7 5.8 7.3 4.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) CENP-H PF05837.12 EGF81189.1 - 2.1 8.8 9.7 1.9 8.9 3.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) BRE1 PF08647.11 EGF81189.1 - 2.1 8.5 14.3 13 5.9 8.2 2.9 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase LPP PF04728.13 EGF81189.1 - 2.6 8.5 5.9 13 6.3 0.7 3.4 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 EGF81189.1 - 2.6 8.0 11.9 1.2 9.1 4.4 3.2 3 1 0 3 3 3 0 Prefoldin subunit FAM76 PF16046.5 EGF81189.1 - 3 7.1 9.2 4 6.7 9.2 1.2 1 0 0 1 1 1 0 FAM76 protein Seryl_tRNA_N PF02403.22 EGF81189.1 - 3.7 7.8 12.1 8.5 6.7 7.1 2.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 EGF81189.1 - 5 7.2 17.2 0.74 9.9 7.7 2.9 2 2 1 3 3 2 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 EGF81189.1 - 6.9 7.4 8.9 13 6.5 2.8 3.0 1 1 2 3 3 3 0 Initiation control protein YabA CC2-LZ PF16516.5 EGF81189.1 - 7 7.1 8.9 7.3 7.0 3.8 2.9 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Sec2p PF06428.11 EGF81189.1 - 7.9 6.5 10.7 50 4.0 6.8 2.9 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Usp PF00582.26 EGF81190.1 - 8e-30 104.2 0.1 1.2e-29 103.6 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family PGM_PMM_I PF02878.16 EGF81190.1 - 0.055 13.2 0.0 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Clat_adaptor_s PF01217.20 EGF81191.1 - 2.6e-20 72.8 2.8 5.6e-19 68.5 2.8 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF1286 PF06939.11 EGF81191.1 - 0.017 15.4 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) IQ_SEC7_PH PF16453.5 EGF81191.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 PH domain Equine_IAV_S2 PF06502.11 EGF81191.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein LTV PF04180.14 EGF81192.1 - 2.6e-71 241.4 20.0 2.5e-70 238.2 20.0 2.2 1 1 0 1 1 1 1 Low temperature viability protein DUF4111 PF13427.6 EGF81192.1 - 0.048 13.8 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) PTPlike_phytase PF14566.6 EGF81192.1 - 3.7 7.6 6.0 2.6 8.2 0.2 2.4 2 1 0 2 2 2 0 Inositol hexakisphosphate DUF908 PF06012.12 EGF81193.1 - 1.3 8.4 7.7 1.5 8.2 7.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PGA2 PF07543.12 EGF81193.1 - 2 8.4 6.5 2.6 8.0 6.5 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 FGF-BP1 PF06473.12 EGF81193.1 - 2.6 7.8 9.0 3.1 7.6 9.0 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4820 PF16091.5 EGF81193.1 - 2.7 7.3 6.1 3.3 7.0 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Zip PF02535.22 EGF81193.1 - 6.5 5.9 5.8 7.4 5.7 5.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGF81193.1 - 7 5.3 6.6 7.3 5.2 6.6 1.1 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 EGF81194.1 - 2.4e-47 161.0 0.0 3.7e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF81194.1 - 3.7e-32 111.0 0.0 5.5e-31 107.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF81194.1 - 7.9e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MRP-L28 PF09812.9 EGF81195.1 - 8.4e-14 52.0 0.3 9e-14 51.9 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PEMT PF04191.13 EGF81196.1 - 5.3e-36 123.2 14.9 3.1e-18 66.1 1.2 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase GCP_N_terminal PF17681.1 EGF81197.1 - 5.8e-13 49.1 1.8 1.5e-12 47.8 1.8 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGF81198.1 - 1e-08 35.1 1.9 1.4e-08 34.6 1.9 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Peptidase_S10 PF00450.22 EGF81199.1 - 1.1e-87 295.1 0.2 1.6e-87 294.7 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase DUF846 PF05832.12 EGF81200.1 - 2.2e-53 180.0 15.1 3e-53 179.6 15.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 EGF81200.1 - 0.19 12.5 6.0 0.33 11.7 2.8 2.1 2 0 0 2 2 2 0 Transmembrane family 220, helix Xpo1 PF08389.12 EGF81201.1 - 1.1e-35 122.9 0.8 3e-34 118.2 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein FANCI_HD1 PF14679.6 EGF81201.1 - 0.031 14.2 0.4 0.93 9.5 0.0 2.6 2 0 0 2 2 2 0 FANCI helical domain 1 EPL1 PF10513.9 EGF81202.1 - 7.6e-16 58.9 0.1 7.6e-16 58.9 0.1 3.7 3 1 0 3 3 3 1 Enhancer of polycomb-like SUI1 PF01253.22 EGF81203.1 - 1.4e-20 73.6 0.7 2.2e-20 73.0 0.7 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Vps39_2 PF10367.9 EGF81204.1 - 1.7e-19 70.3 1.9 5.3e-19 68.7 1.9 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EGF81204.1 - 2.3e-15 56.8 1.1 2.3e-15 56.8 1.1 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EGF81204.1 - 7.3e-08 32.4 0.1 5.4e-06 26.2 0.0 2.4 1 1 1 2 2 2 1 CNH domain Clathrin PF00637.20 EGF81204.1 - 8.4e-07 29.0 10.5 1.3e-06 28.3 1.3 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS DUF4428 PF14471.6 EGF81204.1 - 0.12 12.3 0.2 0.37 10.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) CSRNP_N PF16019.5 EGF81205.1 - 0.39 10.6 4.6 0.69 9.8 4.6 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus STAS PF01740.21 EGF81206.1 - 0.059 13.0 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 STAS domain HEAT PF02985.22 EGF81207.1 - 6.5e-08 32.2 1.3 4.5 7.8 0.0 8.3 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EGF81207.1 - 9.3e-07 29.2 0.7 1.7 9.1 0.0 6.1 5 2 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 EGF81207.1 - 3.7e-05 24.1 4.9 2.8 8.6 0.4 7.7 6 1 0 6 6 6 1 HEAT-like repeat Acyl-CoA_dh_1 PF00441.24 EGF81208.1 - 4e-41 140.7 0.1 9.1e-41 139.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGF81208.1 - 1.6e-39 135.0 0.0 2.9e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGF81208.1 - 2.2e-24 85.5 0.0 3.6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGF81208.1 - 1.6e-12 47.8 0.0 3.6e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Nucleo_LEF-12 PF06256.11 EGF81210.1 - 0.0085 15.9 0.5 0.044 13.5 0.1 1.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus LEF-12 protein Ribosomal_L36 PF00444.18 EGF81211.1 - 4.4e-14 52.4 4.8 6.7e-14 51.8 4.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 FAM212 PF15342.6 EGF81211.1 - 0.058 13.2 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 FAM212 family IMPa_N_2 PF18650.1 EGF81211.1 - 0.081 12.2 0.8 0.098 11.9 0.8 1.1 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain DNA_pol_delta_4 PF04081.13 EGF81212.1 - 2.8e-15 56.8 0.5 7.4e-15 55.4 0.5 1.7 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF737 PF05300.11 EGF81212.1 - 0.048 14.0 3.4 0.064 13.6 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) LMBR1 PF04791.16 EGF81212.1 - 0.28 10.1 1.6 0.34 9.8 1.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein G-alpha PF00503.20 EGF81213.1 - 4.7e-74 249.7 7.9 4.4e-73 246.5 7.9 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF81213.1 - 8.6e-10 38.3 0.6 9.8e-08 31.6 0.2 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF81213.1 - 9.8e-08 31.8 1.0 9.7e-05 22.0 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGF81213.1 - 0.00021 20.8 1.0 0.0011 18.4 0.1 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 EGF81213.1 - 0.0021 18.6 0.2 0.0047 17.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGF81213.1 - 0.0023 18.0 0.1 0.14 12.3 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EGF81213.1 - 0.0053 16.4 1.2 0.018 14.7 0.1 2.2 2 0 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.18 EGF81213.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 EGF81213.1 - 0.046 13.9 5.4 0.36 11.1 0.2 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGF81213.1 - 0.2 11.4 3.5 0.88 9.3 0.2 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EGF81213.1 - 1.2 8.9 3.1 1.3 8.9 0.1 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ORC4_C PF14629.6 EGF81216.1 - 4.1e-36 124.4 0.0 5.3e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 EGF81216.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGF81216.1 - 0.0041 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGF81216.1 - 0.037 14.4 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGF81216.1 - 0.09 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.13 EGF81217.1 - 4.4e-17 62.7 13.3 4.4e-17 62.7 13.3 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pox_A9 PF04835.12 EGF81217.1 - 0.83 9.8 3.9 0.28 11.4 0.8 1.8 1 1 1 2 2 2 0 A9 protein conserved region SSrecog PF03531.14 EGF81219.1 - 7.6e-25 86.6 0.0 3.2e-24 84.6 0.0 2.1 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EGF81219.1 - 1e-22 80.4 0.0 2.6e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like POB3_N PF17292.2 EGF81219.1 - 3.7e-22 78.5 0.0 1e-20 73.9 0.0 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SNF2_N PF00176.23 EGF81220.1 - 6.8e-51 173.0 0.0 1.1e-42 146.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF81220.1 - 7e-14 52.1 0.0 1.6e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGF81220.1 - 1.9e-06 27.6 3.7 1.9e-06 27.6 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGF81220.1 - 6.8e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGF81220.1 - 2.6e-05 24.0 6.1 2.6e-05 24.0 6.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF81220.1 - 9.5e-05 22.3 0.4 9.5e-05 22.3 0.4 3.4 2 2 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGF81220.1 - 0.00024 20.9 5.6 0.00024 20.9 5.6 2.9 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF81220.1 - 0.00045 20.5 4.7 0.00045 20.5 4.7 2.6 2 0 0 2 2 2 1 Ring finger domain DEAD PF00270.29 EGF81220.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 EGF81220.1 - 0.0021 17.9 4.1 0.0021 17.9 4.1 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGF81220.1 - 0.014 15.4 4.9 0.014 15.4 4.9 2.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-Nse PF11789.8 EGF81220.1 - 0.23 11.3 2.8 0.84 9.5 2.8 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.6 EGF81220.1 - 1.4 9.0 9.0 9.2 6.4 3.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Josephin PF02099.17 EGF81221.1 - 1.1e-46 158.9 0.2 5.9e-46 156.5 0.2 1.8 1 1 0 1 1 1 1 Josephin NUDIX-like PF09296.11 EGF81221.1 - 0.065 13.9 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain Ribosomal_L27A PF00828.19 EGF81222.1 - 7.3 7.3 10.6 2.4 8.9 2.1 2.6 1 1 1 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TFIIF_alpha PF05793.12 EGF81223.1 - 0.32 9.6 49.5 0.44 9.1 49.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIIAH PF12685.7 EGF81223.1 - 0.83 9.4 19.6 1.5 8.6 19.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 EGF81223.1 - 0.97 8.7 45.7 1.7 7.9 45.7 1.3 1 0 0 1 1 1 0 BUD22 CCSAP PF15748.5 EGF81223.1 - 1.3 9.2 23.0 2.3 8.3 23.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated V_ATPase_I PF01496.19 EGF81223.1 - 1.6 6.6 11.6 1.9 6.3 11.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 EGF81223.1 - 2.1 6.4 45.4 3.1 5.9 45.4 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EGF81223.1 - 3.3 6.1 45.1 4.5 5.6 45.1 1.1 1 0 0 1 1 1 0 Mpp10 protein SLC12 PF03522.15 EGF81223.1 - 5.1 6.0 13.4 6.3 5.7 13.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 EGF81223.1 - 8.2 4.8 12.8 10 4.5 12.8 1.0 1 0 0 1 1 1 0 Macoilin family Prp18 PF02840.15 EGF81225.1 - 0.0019 18.2 0.2 0.0019 18.2 0.2 1.9 2 0 0 2 2 2 1 Prp18 domain SRA1 PF07304.11 EGF81225.1 - 0.043 13.6 3.1 0.075 12.8 0.1 2.4 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Trypan_glycop PF00913.19 EGF81225.1 - 0.05 12.9 0.0 0.074 12.3 0.0 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Ndc1_Nup PF09531.10 EGF81225.1 - 6.1 5.4 10.0 7.5 5.1 10.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mic1 PF07035.12 EGF81226.1 - 3.4e-20 72.3 1.5 1.2e-19 70.5 1.5 1.9 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Telomere_reg-2 PF10193.9 EGF81226.1 - 0.032 14.7 0.2 2.5 8.6 0.0 2.7 2 0 0 2 2 2 0 Telomere length regulation protein Asp PF00026.23 EGF81228.1 - 0.00061 19.3 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF81228.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal HEAT PF02985.22 EGF81229.1 - 0.12 12.7 0.2 9.6 6.8 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat PP2C PF00481.21 EGF81232.1 - 4.3e-12 46.2 0.0 6.1e-11 42.4 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SlyX PF04102.12 EGF81233.1 - 0.16 12.6 2.1 17 6.1 0.1 2.8 2 0 0 2 2 2 0 SlyX DUF3496 PF12001.8 EGF81234.1 - 0.098 13.0 0.1 0.69 10.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) U83 PF17465.2 EGF81235.1 - 0.069 13.3 0.3 0.17 12.0 0.3 1.6 1 0 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product Tmemb_14 PF03647.13 EGF81236.1 - 7.6e-22 77.9 7.5 8.6e-22 77.7 7.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EGF81236.1 - 0.00027 21.2 1.8 0.00083 19.6 1.1 2.0 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF2781 PF10914.8 EGF81237.1 - 2.3e-22 80.0 12.2 2.8e-22 79.7 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Ufd2P_core PF10408.9 EGF81239.1 - 3.9e-208 693.1 0.0 4.9e-208 692.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EGF81239.1 - 1.5e-27 95.6 0.8 8.3e-27 93.2 0.5 2.5 2 0 0 2 2 2 1 U-box domain SAP130_C PF16014.5 EGF81239.1 - 0.28 10.2 1.6 0.62 9.1 1.6 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus UBA PF00627.31 EGF81241.1 - 3.5e-25 87.5 5.0 7.6e-13 48.1 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EGF81241.1 - 6.6e-25 86.6 17.9 1.1e-24 85.9 17.9 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EGF81241.1 - 2.2e-17 62.6 1.1 4.9e-17 61.5 0.9 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EGF81241.1 - 6.7e-08 32.3 2.1 1.1e-07 31.6 2.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGF81241.1 - 0.0086 16.2 0.1 0.024 14.7 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EGF81241.1 - 0.039 14.0 1.5 0.18 11.8 0.4 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain DUF1421 PF07223.11 EGF81241.1 - 0.044 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) DUF2407 PF10302.9 EGF81241.1 - 0.095 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TFIIA PF03153.13 EGF81241.1 - 3.1 7.7 5.7 3.9 7.4 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rib_recp_KP_reg PF05104.12 EGF81241.1 - 5.2 8.1 20.4 5.3 8.1 8.5 2.3 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Tom5 PF10642.9 EGF81242.1 - 0.00027 20.9 0.5 0.00034 20.6 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase RRM_1 PF00076.22 EGF81243.1 - 9e-35 118.3 0.0 1.3e-15 56.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF81243.1 - 5.1e-05 23.1 0.1 0.46 10.4 0.0 4.6 4 1 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGF81243.1 - 0.013 15.6 0.0 0.92 9.7 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif SPT6_acidic PF14632.6 EGF81243.1 - 6.1 7.5 9.0 1.1e+02 3.4 0.0 2.8 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Prenyltransf PF01255.19 EGF81244.1 - 2.5e-76 256.2 0.0 2.9e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DER1 PF04511.15 EGF81245.1 - 1.1e-59 201.7 9.1 1.2e-59 201.5 9.1 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 EGF81245.1 - 7.4e-06 26.0 6.7 1.1e-05 25.5 6.7 1.2 1 0 0 1 1 1 1 Rhomboid family Pkinase PF00069.25 EGF81246.1 - 1.4e-62 211.5 0.0 1.6e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81246.1 - 1.6e-38 132.5 0.0 1.9e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81246.1 - 1.5e-05 24.5 0.0 5.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGF81246.1 - 0.0019 17.3 1.2 0.18 10.8 0.0 2.1 2 0 0 2 2 2 2 Seadornavirus VP7 Haspin_kinase PF12330.8 EGF81246.1 - 0.0078 15.2 0.1 0.011 14.7 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain PDZ_1 PF12812.7 EGF81247.1 - 4.6e-37 125.9 0.0 3.8e-27 94.1 0.0 3.7 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.6 EGF81247.1 - 4.1e-16 59.1 0.6 1.1e-06 28.9 0.1 4.3 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.6 EGF81247.1 - 1e-15 59.0 0.0 2.6e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 EGF81247.1 - 3.9e-13 49.0 0.2 1.4e-06 28.0 0.1 4.2 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EGF81247.1 - 1.7e-10 41.1 0.1 0.0013 19.1 0.1 3.4 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EGF81247.1 - 0.013 15.4 0.1 2.3 8.2 0.0 3.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EGF81247.1 - 0.083 11.5 0.2 0.12 11.0 0.2 1.1 1 0 0 1 1 1 0 Peptidase S46 FAD_binding_3 PF01494.19 EGF81248.1 - 2e-08 33.9 4.1 8e-05 22.0 0.1 3.6 4 0 0 4 4 4 3 FAD binding domain Pyr_redox_2 PF07992.14 EGF81248.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAA_hydrolase PF01557.18 EGF81250.1 - 3.8e-51 173.8 0.0 5.4e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGF81250.1 - 1.1e-33 115.6 0.0 9.2e-33 112.6 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal CathepsinC_exc PF08773.11 EGF81251.1 - 0.1 12.9 0.6 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Cathepsin C exclusion domain Acyl_transf_3 PF01757.22 EGF81252.1 - 1.2e-13 50.9 38.6 1.2e-13 50.9 38.6 2.5 2 1 0 2 2 2 1 Acyltransferase family DRY_EERY PF09750.9 EGF81253.1 - 2.1e-06 28.1 0.3 2.2e-06 28.0 0.3 1.0 1 0 0 1 1 1 1 Alternative splicing regulator Dimer_Tnp_hAT PF05699.14 EGF81254.1 - 2.9e-17 62.2 0.0 3.2e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region gag-asp_proteas PF13975.6 EGF81255.1 - 0.053 14.1 0.0 3.3 8.3 0.0 2.3 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Dimer_Tnp_hAT PF05699.14 EGF81256.1 - 7.4e-19 67.3 0.0 8e-19 67.2 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 EGF81257.1 - 2.6e-16 59.8 0.0 8e-14 51.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81257.1 - 1.6e-05 24.4 0.0 0.01 15.2 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase DRY_EERY PF09750.9 EGF81258.1 - 5e-26 91.6 0.7 1.3e-25 90.3 0.0 2.0 2 0 0 2 2 2 1 Alternative splicing regulator PPR_long PF17177.4 EGF81259.1 - 2.2e-10 40.3 2.2 2.1e-06 27.3 0.0 3.7 2 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGF81259.1 - 1.1e-05 25.4 0.8 0.0028 17.7 0.1 4.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF81259.1 - 0.00025 21.2 1.4 0.0046 17.1 0.0 3.6 4 1 0 4 4 4 1 PPR repeat family PPR PF01535.20 EGF81259.1 - 0.0069 16.6 0.0 0.094 13.0 0.0 3.0 2 0 0 2 2 2 1 PPR repeat PS_Dcarbxylase PF02666.15 EGF81260.1 - 4.4e-59 199.4 0.0 6.9e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase SNARE_assoc PF09335.11 EGF81261.1 - 2.9e-09 37.4 2.8 2.9e-09 37.4 2.8 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein FTR1 PF03239.14 EGF81262.1 - 1.2e-53 182.3 9.5 1.5e-53 182.0 9.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Synaptobrevin PF00957.21 EGF81262.1 - 0.0025 17.5 0.6 0.0025 17.5 0.6 2.3 2 0 0 2 2 2 1 Synaptobrevin DUF4310 PF14187.6 EGF81262.1 - 0.0026 17.4 2.9 0.0026 17.4 2.9 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4310) DUF5518 PF17647.1 EGF81262.1 - 0.02 15.0 3.4 0.02 15.0 3.4 3.3 4 1 0 4 4 4 0 Family of unknown function (DUF5518) CoA_binding_3 PF13727.6 EGF81262.1 - 0.029 14.4 0.6 0.029 14.4 0.6 2.2 2 0 0 2 2 2 0 CoA-binding domain Phage_holin_3_6 PF07332.11 EGF81262.1 - 3.8 7.6 16.0 4.1 7.5 0.5 3.0 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2516 PF10724.9 EGF81262.1 - 4.4 7.7 9.9 0.44 10.8 4.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) Pox_Ag35 PF03286.14 EGF81263.1 - 0.41 10.4 4.6 1.1 9.0 4.6 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 EGF81263.1 - 0.78 7.9 3.3 1.1 7.4 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIE-A_C PF11521.8 EGF81263.1 - 5.9 7.3 12.1 8.5 6.8 0.0 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha FAM176 PF14851.6 EGF81263.1 - 5.9 6.5 7.1 1.3 8.7 1.9 2.0 2 0 0 2 2 2 0 FAM176 family Cu-oxidase_2 PF07731.14 EGF81264.1 - 2.6e-35 121.1 0.4 2.6e-35 121.1 0.4 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGF81264.1 - 2.9e-34 117.6 2.0 4.4e-31 107.4 1.6 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGF81264.1 - 1.2e-31 110.0 0.5 1.1e-27 97.2 0.0 3.2 3 0 0 3 3 3 3 Multicopper oxidase SDA1 PF05285.12 EGF81265.1 - 3.3e-46 158.3 54.1 4.7e-40 138.1 30.4 3.5 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 EGF81265.1 - 2.3e-23 82.3 0.6 5.7e-22 77.8 0.0 3.3 4 0 0 4 4 4 1 NUC130/3NT domain Asp4 PF16996.5 EGF81265.1 - 0.0088 15.8 2.0 0.043 13.6 2.0 2.2 1 0 0 1 1 1 1 Accessory secretory protein Sec Asp4 Cnd1 PF12717.7 EGF81265.1 - 0.012 15.6 2.4 0.05 13.6 2.4 2.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CDC45 PF02724.14 EGF81265.1 - 5.3 5.2 26.2 0.89 7.8 18.2 2.5 3 0 0 3 3 3 0 CDC45-like protein SLAIN PF15301.6 EGF81265.1 - 9.8 5.3 8.7 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 SLAIN motif-containing family API5 PF05918.11 EGF81266.1 - 1.7e-49 169.1 9.4 2.4e-49 168.6 9.4 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HNH_2 PF13391.6 EGF81267.1 - 8.4e-06 25.8 0.4 0.0004 20.4 0.0 2.9 3 0 0 3 3 3 1 HNH endonuclease Baculo_DNA_bind PF04786.12 EGF81267.1 - 0.053 12.9 0.4 0.11 11.8 0.4 1.5 1 0 0 1 1 1 0 ssDNA binding protein Cytochrome_C7 PF14522.6 EGF81267.1 - 0.23 11.5 1.7 7.2 6.7 1.7 2.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF81267.1 - 1.1 9.0 4.8 5.7 6.8 0.2 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) AAA_22 PF13401.6 EGF81268.1 - 0.019 15.3 0.0 0.19 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain HNH_2 PF13391.6 EGF81269.1 - 3.4e-06 27.1 0.2 0.00017 21.6 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease Cytochrome_C7 PF14522.6 EGF81269.1 - 0.079 13.0 1.8 1.9 8.5 0.2 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c HNH PF01844.23 EGF81269.1 - 0.083 13.1 1.2 1.1 9.5 1.2 2.5 1 1 0 1 1 1 0 HNH endonuclease Paired_CXXCH_1 PF09699.10 EGF81269.1 - 0.38 10.5 5.0 3 7.7 0.2 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) AAA_22 PF13401.6 EGF81270.1 - 0.0021 18.3 0.0 0.018 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Ctr PF04145.15 EGF81273.1 - 0.00011 22.9 0.0 0.00012 22.7 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DJ-1_PfpI PF01965.24 EGF81274.1 - 0.031 14.1 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family DUF4964 PF16334.5 EGF81274.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Polysacc_deac_1 PF01522.21 EGF81275.1 - 3.1e-28 98.1 0.0 4.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase RCDG1 PF15725.5 EGF81275.1 - 8.8 6.8 8.8 1.5 9.3 4.6 1.9 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Mon1 PF03164.14 EGF81276.1 - 1.6e-129 432.6 0.7 1.8e-129 432.4 0.7 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 MF_alpha_N PF05436.11 EGF81278.1 - 0.0028 17.5 0.1 0.0063 16.4 0.1 1.6 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus DUF3450 PF11932.8 EGF81278.1 - 0.0044 16.4 0.3 0.0091 15.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Tup_N PF08581.10 EGF81278.1 - 2.7 8.4 7.7 0.7 10.2 3.9 2.1 2 0 0 2 2 2 0 Tup N-terminal LIM PF00412.22 EGF81279.1 - 2.9e-07 30.6 1.8 5.1e-07 29.8 1.8 1.5 1 1 0 1 1 1 1 LIM domain Zn-ribbon_8 PF09723.10 EGF81279.1 - 0.11 12.7 1.8 0.46 10.6 1.7 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf-RING_7 PF02591.15 EGF81279.1 - 0.11 12.7 2.4 2.4 8.4 0.1 2.7 3 0 0 3 3 3 0 C4-type zinc ribbon domain RhoGAP PF00620.27 EGF81280.1 - 1.9e-38 131.6 0.0 2.3e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 EGF81280.1 - 0.087 12.0 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) FAM220 PF15487.6 EGF81280.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 FAM220 family Ras PF00071.22 EGF81281.1 - 8.8e-58 194.5 0.2 1e-57 194.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF81281.1 - 7e-33 113.4 0.0 1.1e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF81281.1 - 1.1e-13 51.1 0.0 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF81281.1 - 8.1e-08 32.3 0.0 1.6e-07 31.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF81281.1 - 3.3e-06 26.6 0.1 4.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGF81281.1 - 9.2e-06 25.3 0.1 0.00022 20.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 EGF81281.1 - 5.1e-05 22.7 0.4 0.0098 15.2 0.1 2.2 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EGF81281.1 - 7.2e-05 22.8 0.1 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 EGF81281.1 - 0.00046 20.0 0.1 0.16 11.7 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGF81281.1 - 0.003 17.4 0.5 0.098 12.4 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EGF81281.1 - 0.0068 15.9 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGF81281.1 - 0.0092 16.4 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF81281.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGF81281.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EGF81281.1 - 0.021 14.4 0.0 0.099 12.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGF81281.1 - 0.023 14.4 0.5 0.058 13.1 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGF81281.1 - 0.024 14.1 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGF81281.1 - 0.037 13.9 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 NTPase Glyco_hydro_75 PF07335.11 EGF81281.1 - 0.047 14.0 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 FeoB_N PF02421.18 EGF81281.1 - 0.069 12.7 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EGF81281.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EGF81281.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EGF81281.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGF81281.1 - 0.2 12.1 0.6 0.32 11.5 0.6 1.7 1 1 0 1 1 1 0 ABC transporter Rif1_N PF12231.8 EGF81282.1 - 4.8e-27 94.9 5.2 9.3e-27 94.0 5.2 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Dicer_dimer PF03368.14 EGF81282.1 - 0.016 15.4 0.0 0.44 10.7 0.0 2.8 2 0 0 2 2 2 0 Dicer dimerisation domain Arm PF00514.23 EGF81282.1 - 0.028 14.5 0.5 4.9 7.3 0.1 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FtsJ PF01728.19 EGF81283.1 - 3e-64 216.4 0.1 3.8e-64 216.1 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Tcf25 PF04910.14 EGF81284.1 - 6e-92 308.4 4.2 8.2e-92 308.0 4.2 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Stm1_N PF09598.10 EGF81284.1 - 0.00026 21.8 3.6 0.00059 20.6 3.6 1.6 1 0 0 1 1 1 1 Stm1 FCD PF07729.12 EGF81284.1 - 0.0033 17.9 0.1 0.58 10.6 0.0 2.8 3 0 0 3 3 3 1 FCD domain TPR_19 PF14559.6 EGF81284.1 - 0.068 13.7 0.1 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RestrictionSfiI PF11487.8 EGF81284.1 - 0.16 11.8 0.9 0.3 10.9 0.9 1.4 1 0 0 1 1 1 0 Type II restriction enzyme SfiI GET2 PF08690.10 EGF81284.1 - 0.27 10.9 3.4 0.53 9.9 3.4 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Amidohydro_3 PF07969.11 EGF81285.1 - 1.4e-21 77.5 0.8 5.1e-11 42.7 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 EGF81285.1 - 1.2e-12 47.8 0.1 8.8e-09 35.1 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family IQ PF00612.27 EGF81286.1 - 9.8e-06 24.9 1.8 7.4e-05 22.2 0.4 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif RhoGEF PF00621.20 EGF81286.1 - 5.2e-05 23.6 0.2 5.2e-05 23.6 0.2 5.1 3 2 1 4 4 4 2 RhoGEF domain DUF1465 PF07323.12 EGF81286.1 - 0.36 10.7 9.5 8 6.3 5.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) Complex1_49kDa PF00346.19 EGF81286.1 - 0.84 8.7 5.3 3.3 6.7 1.9 2.5 2 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF4061 PF13270.6 EGF81286.1 - 5.4 7.4 10.6 0.49 10.7 2.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) FSIP1 PF15554.6 EGF81287.1 - 7.9e-05 21.9 7.9 0.0053 15.9 0.2 3.2 2 1 0 2 2 2 2 FSIP1 family FHA PF00498.26 EGF81288.1 - 3.6e-17 62.5 0.0 7.4e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGF81288.1 - 4.7e-05 23.6 0.0 0.0026 18.0 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ribosomal_S9 PF00380.19 EGF81289.1 - 3.3e-34 118.0 0.2 3.7e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 UPF0203 PF05254.12 EGF81290.1 - 0.00016 21.8 5.8 0.00021 21.5 5.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Ndufs5 PF10200.9 EGF81290.1 - 0.00081 19.6 0.9 0.00086 19.5 0.9 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Defensin_5 PF18251.1 EGF81290.1 - 0.073 13.2 1.3 0.11 12.6 1.3 1.4 1 1 0 1 1 1 0 Fungal defensin Copsin adh_short_C2 PF13561.6 EGF81291.1 - 6.4e-13 48.8 0.1 9.4e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF81291.1 - 4.2e-12 45.9 0.2 6e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EGF81291.1 - 0.00057 19.4 0.1 0.0037 16.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family XAP5 PF04921.14 EGF81292.1 - 3.2e-74 249.9 14.3 5.1e-74 249.3 14.3 1.5 1 1 0 1 1 1 1 XAP5, circadian clock regulator COX5B PF01215.19 EGF81293.1 - 4.4e-25 87.9 0.0 4.7e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EGF81293.1 - 0.0028 17.7 1.2 0.0041 17.1 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain zinc_ribbon_4 PF13717.6 EGF81293.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MPLKIP PF15502.6 EGF81293.1 - 0.036 14.3 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein zf-C4_Topoisom PF01396.19 EGF81293.1 - 0.037 13.8 0.4 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Desulfoferrod_N PF06397.12 EGF81293.1 - 0.085 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_5 PF13719.6 EGF81293.1 - 0.11 12.3 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain CX9C PF16860.5 EGF81294.1 - 7.4e-21 73.9 8.8 7e-15 54.8 0.4 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EGF81294.1 - 2.5e-05 24.3 7.6 0.028 14.6 1.4 3.2 1 1 2 3 3 3 3 CHCH domain Cmc1 PF08583.10 EGF81294.1 - 0.0014 18.6 10.3 0.14 12.2 1.5 2.6 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EGF81294.1 - 0.0015 18.8 9.0 0.23 11.8 2.3 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 EGF81294.1 - 0.0039 17.3 8.6 0.38 11.0 0.7 2.3 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein MTCP1 PF08991.10 EGF81294.1 - 0.004 17.3 10.1 0.078 13.2 3.0 2.2 1 1 1 2 2 2 2 Mature-T-Cell Proliferation I type COX6B PF02297.17 EGF81294.1 - 0.012 15.8 7.1 0.22 11.8 0.8 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.13 EGF81294.1 - 0.028 14.2 6.3 0.18 11.5 1.3 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CREPT PF16566.5 EGF81294.1 - 0.041 14.1 0.3 0.052 13.7 0.3 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour COX17 PF05051.13 EGF81294.1 - 0.059 13.7 7.3 0.18 12.2 1.8 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 EGF81294.1 - 0.085 13.1 7.8 0.66 10.3 7.8 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) APP_E2 PF12925.7 EGF81294.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DUF2462 PF09495.10 EGF81295.1 - 3.6e-14 53.3 10.3 3.6e-14 53.3 10.3 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Asp PF00026.23 EGF81296.1 - 6.9e-12 45.4 4.4 7e-11 42.1 4.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF81296.1 - 0.00046 20.0 0.4 0.0022 17.8 0.4 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal STD1 PF17235.2 EGF81296.1 - 0.046 13.4 0.3 0.079 12.6 0.3 1.4 1 0 0 1 1 1 0 STD1/MTH1 DUF4246 PF14033.6 EGF81297.1 - 4.6e-98 329.3 0.0 5.6e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF2951 PF11166.8 EGF81298.1 - 0.01 16.1 2.2 0.015 15.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Mitoc_L55 PF09776.9 EGF81298.1 - 0.072 12.8 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Peptidase_S13 PF02113.15 EGF81299.1 - 0.0056 15.4 0.4 0.0068 15.2 0.4 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Phasin PF05597.11 EGF81299.1 - 0.051 13.6 2.3 0.53 10.3 2.3 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HSP70 PF00012.20 EGF81299.1 - 0.48 8.6 4.6 0.51 8.5 4.6 1.0 1 0 0 1 1 1 0 Hsp70 protein Gemin7 PF11095.8 EGF81300.1 - 1.9e-13 50.1 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) DarA_N PF18788.1 EGF81300.1 - 0.0025 17.9 0.1 0.0098 16.0 0.0 1.8 2 0 0 2 2 2 1 Defence against restriction A N-terminal FtsJ PF01728.19 EGF81301.1 - 3e-16 60.0 0.0 2.1e-15 57.3 0.0 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase RIBIOP_C PF04950.12 EGF81302.1 - 3.1e-116 387.9 0.0 5.5e-116 387.1 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGF81302.1 - 2.1e-24 85.4 0.0 5.7e-24 84.0 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain ResIII PF04851.15 EGF81303.1 - 4.2e-22 79.0 0.0 7.6e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF81303.1 - 1.2e-15 57.8 0.0 1.4e-14 54.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGF81303.1 - 2.8e-09 37.0 0.0 8.7e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGF81303.1 - 8.4e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SNF2_N PF00176.23 EGF81303.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.9 EGF81303.1 - 0.029 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EGF81303.1 - 0.06 13.1 0.2 6 6.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EGF81303.1 - 0.076 13.3 0.0 0.88 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain RE_LlaMI PF09562.10 EGF81304.1 - 0.013 15.1 0.7 0.019 14.6 0.7 1.1 1 0 0 1 1 1 0 LlaMI restriction endonuclease CBM39 PF15886.5 EGF81304.1 - 0.11 12.3 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) F-box PF00646.33 EGF81305.1 - 0.0011 18.8 0.1 0.023 14.6 0.0 2.7 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 EGF81305.1 - 0.12 12.1 0.3 2 8.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Hs1pro-1_C PF07014.12 EGF81305.1 - 0.15 11.5 0.2 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Hs1pro-1 protein C-terminus 3HCDH_N PF02737.18 EGF81306.1 - 1.8e-59 200.7 1.0 2.6e-59 200.2 1.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGF81306.1 - 1.2e-30 106.0 0.0 2.3e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 EGF81306.1 - 5.4e-05 22.6 0.4 0.00012 21.5 0.4 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EGF81306.1 - 0.00032 20.9 0.2 0.00053 20.2 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGF81306.1 - 0.001 19.1 0.1 0.0019 18.2 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 EGF81306.1 - 0.0011 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGF81306.1 - 0.0016 18.6 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 EGF81306.1 - 0.0017 17.8 0.1 0.0037 16.6 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EGF81306.1 - 0.0024 17.0 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EGF81306.1 - 0.0039 17.7 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DFP PF04127.15 EGF81306.1 - 0.0099 15.7 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein XdhC_C PF13478.6 EGF81306.1 - 0.012 16.1 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 EGF81306.1 - 0.029 15.0 0.2 0.059 14.0 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EGF81306.1 - 0.041 14.3 0.1 0.07 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EGF81306.1 - 0.042 14.1 0.1 0.091 13.0 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EGF81306.1 - 0.042 13.4 0.1 0.078 12.6 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EGF81306.1 - 0.049 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGF81306.1 - 0.063 12.5 0.1 0.11 11.7 0.1 1.3 1 1 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EGF81306.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DSPc PF00782.20 EGF81307.1 - 0.0006 19.6 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF81307.1 - 0.0045 16.6 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGF81307.1 - 0.044 13.9 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Spo7 PF03907.13 EGF81308.1 - 1.4e-14 54.1 3.5 2.7e-12 46.6 0.1 2.1 1 1 1 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.9 EGF81308.1 - 1e-10 42.0 0.1 1.5e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 188 DUF4271 PF14093.6 EGF81308.1 - 0.007 16.3 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Lebercilin PF15619.6 EGF81310.1 - 0.098 12.3 14.9 0.16 11.6 14.9 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Exonuc_VII_L PF02601.15 EGF81310.1 - 0.2 11.2 6.6 0.27 10.7 6.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 EGF81310.1 - 1.9 8.2 7.3 3.8 7.2 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF3421 PF11901.8 EGF81311.1 - 4.2e-24 84.8 0.6 1.6e-11 44.2 0.2 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF3421) Lipase_3 PF01764.25 EGF81312.1 - 3.1e-08 33.6 0.0 1.1e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGF81312.1 - 0.0095 16.6 0.1 0.021 15.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EGF81312.1 - 0.2 11.6 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Gram_pos_anchor PF00746.21 EGF81312.1 - 0.29 11.1 1.6 0.5 10.3 0.2 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DnaJ_C PF01556.18 EGF81313.1 - 4.9e-38 130.5 0.2 6.4e-38 130.2 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGF81313.1 - 1.7e-26 92.1 3.0 2.6e-26 91.5 3.0 1.3 1 0 0 1 1 1 1 DnaJ domain AAA_6 PF12774.7 EGF81314.1 - 2.7e-160 532.7 0.0 1.1e-159 530.8 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF81314.1 - 1.1e-136 456.1 17.7 1.1e-136 456.1 17.7 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGF81314.1 - 6.4e-114 380.3 0.0 1.9e-113 378.8 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGF81314.1 - 3.2e-105 351.1 0.2 1.6e-104 348.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGF81314.1 - 7.3e-91 303.2 2.7 7.3e-91 303.2 2.7 3.7 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF81314.1 - 6.7e-80 266.9 0.1 2.9e-77 258.3 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF81314.1 - 8.3e-63 211.1 0.0 2.5e-62 209.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF81314.1 - 9.7e-48 162.9 4.1 9.7e-48 162.9 4.1 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGF81314.1 - 2.4e-47 159.9 0.0 6.6e-45 152.0 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGF81314.1 - 1.5e-29 102.6 1.3 6e-29 100.8 0.2 2.8 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGF81314.1 - 1.6e-21 76.7 0.0 1.5e-06 28.2 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGF81314.1 - 1.5e-17 63.7 0.4 1.2e-16 60.8 0.1 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 EGF81314.1 - 3e-06 27.7 0.2 1.5 9.3 0.1 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF81314.1 - 1.5e-05 25.3 0.5 20 5.4 0.0 6.1 6 0 0 6 6 5 0 AAA domain AAA_16 PF13191.6 EGF81314.1 - 0.0016 18.9 0.9 2.5 8.4 0.0 4.3 6 0 0 6 6 2 1 AAA ATPase domain AAA_18 PF13238.6 EGF81314.1 - 0.0022 18.5 0.0 0.25 11.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain SesA PF17107.5 EGF81314.1 - 0.0039 17.4 1.6 2.3 8.4 0.5 3.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases RNA_helicase PF00910.22 EGF81314.1 - 0.0065 16.8 0.0 4.1 7.8 0.0 3.5 3 0 0 3 3 3 1 RNA helicase ATG16 PF08614.11 EGF81314.1 - 0.015 15.6 11.0 0.012 15.8 0.8 3.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AAA_24 PF13479.6 EGF81314.1 - 0.11 12.2 2.0 10 5.7 0.0 4.1 5 0 0 5 5 3 0 AAA domain AAA_30 PF13604.6 EGF81314.1 - 0.33 10.6 1.3 3 7.5 0.3 2.7 3 0 0 3 3 3 0 AAA domain DUF948 PF06103.11 EGF81314.1 - 3.2 8.1 4.9 18 5.7 0.2 3.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FKBP_C PF00254.28 EGF81315.1 - 1.2e-23 83.2 0.0 1.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EMP24_GP25L PF01105.24 EGF81316.1 - 3.9e-20 72.6 1.1 4.8e-20 72.3 1.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNA_pol_Rpb1_2 PF00623.20 EGF81316.1 - 0.06 13.6 0.1 0.068 13.4 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 DUF1206 PF06724.11 EGF81316.1 - 0.065 13.3 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Myb_DNA-binding PF00249.31 EGF81317.1 - 1.6e-18 66.6 0.5 3.4e-05 24.0 0.0 5.2 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF81317.1 - 1.5e-09 37.9 1.3 0.0064 16.7 0.1 5.0 5 0 0 5 5 5 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EGF81317.1 - 0.00047 20.2 0.0 0.87 9.7 0.0 3.4 3 0 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain HNH_5 PF14279.6 EGF81317.1 - 0.084 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 HNH endonuclease PQ-loop PF04193.14 EGF81318.1 - 2.6e-07 30.3 2.9 2.6e-07 30.3 2.9 1.6 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 EGF81318.1 - 0.0032 17.5 5.7 0.0044 17.0 5.7 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange DUF2244 PF10003.9 EGF81318.1 - 0.12 12.0 3.2 0.16 11.6 3.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF3262 PF11660.8 EGF81318.1 - 0.13 12.7 0.6 0.13 12.7 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) DUF2207 PF09972.9 EGF81318.1 - 0.18 10.5 2.9 0.19 10.4 2.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3487 PF11990.8 EGF81318.1 - 0.68 9.8 7.3 0.71 9.8 6.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) Glyco_hydro_26 PF02156.15 EGF81320.1 - 1.2e-07 31.5 3.2 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 EGF81320.1 - 0.089 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 EF hand Ribosomal_L13 PF00572.18 EGF81321.1 - 3.2e-10 40.3 0.0 3.2e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein L13 Ran_BP1 PF00638.18 EGF81322.1 - 9.4e-49 164.7 1.2 1.8e-48 163.9 1.2 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EGF81322.1 - 0.00041 20.3 0.5 0.0022 17.9 0.5 1.9 1 1 0 1 1 1 1 WH1 domain Rhodanese PF00581.20 EGF81325.1 - 4.7e-11 43.2 0.0 6e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Thymidylat_synt PF00303.19 EGF81326.1 - 6.7e-106 353.3 0.0 7.9e-106 353.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Ank_2 PF12796.7 EGF81327.1 - 2.6e-10 40.7 1.3 0.015 15.9 0.2 4.4 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF81327.1 - 0.00014 22.4 5.8 2.9 8.6 0.0 5.7 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF81327.1 - 0.037 14.4 0.4 1 9.8 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Trypsin_2 PF13365.6 EGF81328.1 - 1.3e-32 113.8 0.8 2.5e-32 112.9 0.8 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGF81328.1 - 1.2e-13 51.4 0.1 2.5e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGF81328.1 - 5.4e-11 42.7 0.0 2e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGF81328.1 - 1.5e-09 37.6 0.1 4.8e-08 32.7 0.2 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EGF81328.1 - 2.5e-06 27.7 0.0 1.4e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EGF81328.1 - 0.0051 15.5 0.7 0.98 8.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S7 PF00949.21 EGF81328.1 - 0.0091 15.8 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S32 PF05579.13 EGF81328.1 - 0.018 14.2 4.8 0.33 10.1 0.5 2.2 1 1 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.6 EGF81328.1 - 0.021 14.8 0.1 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF31 PF01732.16 EGF81328.1 - 0.028 14.0 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative peptidase (DUF31) Peptidase_S29 PF02907.15 EGF81328.1 - 0.045 13.5 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Lipase_3 PF01764.25 EGF81329.1 - 1.9e-06 27.8 0.0 4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGF81329.1 - 0.087 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF81329.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGF81329.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.22 EGF81330.1 - 1.5e-76 258.1 0.0 1.4e-75 254.8 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EGF81331.1 - 2.3e-89 300.3 0.0 2.8e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M28 PF04389.17 EGF81332.1 - 1.5e-29 103.1 0.0 4.3e-29 101.6 0.0 1.7 1 1 1 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGF81332.1 - 0.00023 20.9 0.1 0.00056 19.7 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 NVEALA PF14055.6 EGF81332.1 - 3.5 7.7 5.1 5 7.2 0.2 3.0 3 0 0 3 3 3 0 NVEALA protein Rhomboid PF01694.22 EGF81334.1 - 9.7e-05 22.4 8.9 0.00082 19.4 8.9 2.4 1 1 0 1 1 1 1 Rhomboid family DUF2834 PF11196.8 EGF81335.1 - 1.6 9.1 13.4 1.8 9.0 2.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2834) DUF716 PF04819.12 EGF81335.1 - 2.6 7.7 7.9 0.13 11.9 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF716) Trp_oprn_chp PF09534.10 EGF81335.1 - 4 7.2 5.9 1.5 8.6 2.7 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DEC-1_N PF04625.13 EGF81337.1 - 0.009 15.1 3.2 0.011 14.8 3.2 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF2380 PF09533.10 EGF81337.1 - 0.2 11.3 0.2 0.4 10.3 0.1 1.4 1 1 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) SOG2 PF10428.9 EGF81337.1 - 0.44 9.7 7.0 0.53 9.4 7.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDC27 PF09507.10 EGF81337.1 - 0.54 9.6 4.5 0.67 9.3 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1180 PF06679.12 EGF81337.1 - 8.5 6.8 10.6 4.5 7.7 8.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SET PF00856.28 EGF81338.1 - 3.9e-09 37.1 0.1 1.5e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGF81338.1 - 8.4e-08 33.0 0.4 2.4e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Glyco_transf_34 PF05637.12 EGF81338.1 - 0.021 14.6 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family DUF1957 PF09210.11 EGF81339.1 - 0.064 13.7 0.1 9.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) ATP11 PF06644.11 EGF81341.1 - 6.1e-64 216.4 5.8 6.1e-64 216.4 5.8 1.5 2 0 0 2 2 2 1 ATP11 protein WH2 PF02205.20 EGF81341.1 - 0.0048 16.7 0.2 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 WH2 motif SelR PF01641.18 EGF81342.1 - 2.6e-51 172.8 0.1 3e-51 172.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.14 EGF81342.1 - 0.021 15.1 0.4 0.25 11.7 0.2 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ADD_ATRX PF17981.1 EGF81342.1 - 0.034 14.0 0.2 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Cysteine Rich ADD domain Yippee-Mis18 PF03226.14 EGF81342.1 - 0.039 14.1 0.9 0.19 12.0 0.9 1.9 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 EGF81342.1 - 0.046 13.5 0.2 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein RIG-I_C-RD PF11648.8 EGF81342.1 - 0.079 13.2 0.4 4.5 7.5 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I DZR PF12773.7 EGF81342.1 - 0.16 12.0 4.3 1.2 9.2 2.7 2.3 1 1 2 3 3 3 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 EGF81342.1 - 0.16 11.7 1.7 6.8 6.5 0.2 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Mss51 PF13824.6 EGF81342.1 - 0.32 11.1 3.3 0.98 9.6 0.3 2.7 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.12 EGF81342.1 - 0.49 9.9 5.1 8.2 6.0 0.2 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf-HIT PF04438.16 EGF81342.1 - 0.64 9.9 3.9 0.42 10.5 0.5 2.1 2 0 0 2 2 2 0 HIT zinc finger Uds1 PF15456.6 EGF81343.1 - 2.2e-18 66.7 0.2 2.2e-18 66.7 0.2 10.1 5 2 3 9 9 9 2 Up-regulated During Septation HR1 PF02185.16 EGF81343.1 - 0.0035 17.4 0.3 0.0035 17.4 0.3 9.7 9 1 0 9 9 9 2 Hr1 repeat COMM_domain PF07258.14 EGF81343.1 - 3 8.0 12.5 0.54 10.4 2.7 4.5 3 0 0 3 3 3 0 COMM domain zf-HIT PF04438.16 EGF81344.1 - 1.1e-09 37.9 8.0 2.8e-09 36.7 8.0 1.7 1 0 0 1 1 1 1 HIT zinc finger G-gamma PF00631.22 EGF81345.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 GGL domain HAMP PF00672.25 EGF81346.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 HAMP domain DUF3600 PF12207.8 EGF81346.1 - 0.063 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Pep3_Vps18 PF05131.14 EGF81347.1 - 4e-42 143.5 1.5 5.5e-42 143.1 0.3 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGF81347.1 - 2.5e-09 37.2 9.5 1.7e-07 31.2 0.3 3.7 3 1 1 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EGF81347.1 - 4.8e-05 23.8 0.0 0.00015 22.2 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 EGF81347.1 - 0.0018 18.1 1.1 0.0053 16.6 1.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF81347.1 - 0.0022 17.9 1.1 0.0057 16.6 1.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF81347.1 - 0.0022 18.0 0.4 0.0067 16.4 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGF81347.1 - 0.004 17.4 1.0 0.01 16.1 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGF81347.1 - 0.0067 16.5 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGF81347.1 - 0.0089 15.7 3.5 0.028 14.2 3.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGF81347.1 - 0.015 15.1 2.8 0.053 13.4 2.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGF81347.1 - 0.018 14.7 0.6 0.038 13.6 0.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 EGF81347.1 - 0.035 14.1 0.9 0.075 13.1 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger TAFH PF07531.14 EGF81347.1 - 0.037 14.1 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 NHR1 homology to TAF zf-RING_2 PF13639.6 EGF81347.1 - 0.58 10.5 6.9 0.054 13.8 1.6 2.1 2 0 0 2 2 2 0 Ring finger domain CIA30 PF08547.12 EGF81348.1 - 3e-38 131.4 0.0 4.8e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 EGF81348.1 - 0.0027 17.7 0.1 0.0061 16.5 0.1 1.7 1 1 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain NGP1NT PF08153.12 EGF81349.1 - 1.8e-47 160.7 0.0 3.8e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGF81349.1 - 1.1e-17 64.1 0.5 1e-12 48.2 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF81349.1 - 3.7e-06 26.5 0.1 0.0002 20.9 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF81349.1 - 0.00017 21.7 0.8 1.7 8.6 0.0 4.5 3 1 1 4 4 4 1 Dynamin family RsgA_GTPase PF03193.16 EGF81349.1 - 0.00022 21.2 0.0 0.00084 19.3 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGF81349.1 - 0.00024 20.6 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGF81349.1 - 0.052 13.8 0.9 7.2 6.9 0.0 3.3 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Metal_resist PF13801.6 EGF81350.1 - 0.068 13.4 0.4 0.21 11.8 0.1 1.8 1 1 1 2 2 2 0 Heavy-metal resistance STELLO PF03385.17 EGF81350.1 - 0.08 11.7 1.7 0.095 11.5 1.7 1.0 1 0 0 1 1 1 0 STELLO glycosyltransferases Ly49 PF08391.10 EGF81350.1 - 6.9 7.1 8.8 1 9.8 3.2 2.0 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region GNAT_acetyltr_2 PF13718.6 EGF81350.1 - 6.9 6.0 8.9 0.26 10.6 1.2 2.0 1 1 1 2 2 2 0 GNAT acetyltransferase 2 FokI_C PF02980.16 EGF81351.1 - 0.0045 17.0 0.8 0.0065 16.5 0.8 1.2 1 0 0 1 1 1 1 Restriction endonuclease FokI, catalytic domain CENP-H PF05837.12 EGF81351.1 - 0.063 13.7 2.6 0.099 13.1 2.6 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 EGF81351.1 - 0.072 12.4 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_II_R PF09551.10 EGF81351.1 - 0.54 10.7 4.0 0.99 9.9 3.9 1.4 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Tenui_NCP PF04876.12 EGF81351.1 - 1.2 8.7 3.7 1.3 8.6 1.3 2.0 2 1 0 2 2 2 0 Tenuivirus major non-capsid protein FapA PF03961.13 EGF81353.1 - 0.058 12.0 13.2 0.076 11.6 13.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 EGF81353.1 - 0.34 11.3 5.6 0.14 12.6 1.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCDC84 PF14968.6 EGF81353.1 - 0.46 10.0 12.8 0.56 9.8 12.8 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DUF4446 PF14584.6 EGF81353.1 - 2.9 7.9 10.8 0.37 10.8 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2203 PF09969.9 EGF81353.1 - 9.2 7.0 9.0 1.2 9.9 3.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MPC PF03650.13 EGF81355.1 - 1.2e-42 144.5 0.2 1.4e-42 144.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_pol_viral_C PF00336.18 EGF81356.1 - 0.016 14.7 0.8 0.025 14.0 0.8 1.3 1 1 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Barwin PF00967.17 EGF81357.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Barwin family Trypan_PARP PF05887.11 EGF81357.1 - 0.015 15.3 18.7 0.041 13.9 18.4 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 EGF81357.1 - 0.042 13.0 5.0 0.06 12.5 5.0 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 TonB_N PF16031.5 EGF81357.1 - 0.048 14.2 23.1 0.079 13.5 23.1 1.3 1 0 0 1 1 1 0 TonB polyproline region SOG2 PF10428.9 EGF81357.1 - 2.1 7.4 12.9 2.3 7.3 12.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BES1_N PF05687.13 EGF81357.1 - 3.1 8.2 10.2 5.4 7.4 10.2 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal TPR_1 PF00515.28 EGF81358.1 - 2.5e-33 112.5 12.0 2.3e-06 27.2 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGF81358.1 - 5e-31 104.3 10.2 0.00024 21.0 0.2 10.9 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81358.1 - 2.1e-27 93.0 6.8 0.0062 16.7 0.0 9.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGF81358.1 - 5.5e-19 68.5 5.8 2.4e-05 24.9 0.3 7.0 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81358.1 - 5.8e-19 68.4 1.0 9.5e-05 22.8 0.0 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGF81358.1 - 1.5e-17 63.0 7.9 2.1e-05 24.1 0.0 6.8 5 2 2 7 7 7 4 TPR repeat TPR_14 PF13428.6 EGF81358.1 - 1.5e-15 56.5 1.7 0.087 13.7 0.0 7.4 5 3 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF81358.1 - 1.8e-15 56.9 8.4 6.3e-05 23.1 0.0 5.6 4 2 2 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGF81358.1 - 2.9e-15 55.8 13.1 0.027 15.1 0.4 9.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81358.1 - 5.1e-15 55.5 17.4 0.016 15.5 0.1 8.4 7 3 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGF81358.1 - 1.1e-12 47.0 0.2 0.84 9.8 0.1 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF81358.1 - 1.4e-10 40.8 8.7 0.042 14.2 0.1 7.8 9 1 1 10 10 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGF81358.1 - 4.3e-06 26.8 0.8 11 6.3 0.0 6.0 5 2 1 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.8 EGF81358.1 - 0.0044 16.0 2.0 0.11 11.4 0.1 3.2 4 0 0 4 4 4 1 NMDA receptor-regulated protein 1 DUF410 PF04190.13 EGF81358.1 - 0.026 14.3 1.8 4.9 6.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF410) ChAPs PF09295.10 EGF81358.1 - 0.032 13.2 0.2 6.4 5.7 0.1 3.1 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EGF81358.1 - 0.037 13.9 11.8 4 7.4 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 EGF81358.1 - 0.052 13.3 1.3 3.2 7.4 0.1 3.8 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 EGF81358.1 - 0.079 13.0 5.5 4.5 7.4 1.6 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 EGF81358.1 - 0.11 11.9 2.8 3.9 6.8 0.1 3.6 2 2 3 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 EGF81358.1 - 0.22 11.2 5.6 0.065 12.9 0.3 2.8 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EGF81358.1 - 1.3 9.9 5.8 68 4.5 0.5 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat PADR1 PF08063.12 EGF81359.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 PADR1 (NUC008) domain Calci_bind_CcbP PF11535.8 EGF81359.1 - 0.075 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Calcium binding Peptidase_S41 PF03572.18 EGF81360.1 - 3.7e-14 52.6 0.0 7.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.24 EGF81360.1 - 0.024 15.0 0.1 0.052 13.9 0.1 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_4 PF17816.1 EGF81360.1 - 0.037 14.4 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 PDZ domain BUD22 PF09073.10 EGF81362.1 - 0.0045 16.4 28.7 0.0056 16.1 28.7 1.1 1 0 0 1 1 1 1 BUD22 Pex14_N PF04695.13 EGF81362.1 - 0.013 16.2 4.1 0.013 16.2 4.1 3.8 2 1 2 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop14 PF04147.12 EGF81362.1 - 0.24 9.6 27.1 0.36 9.0 27.1 1.3 1 0 0 1 1 1 0 Nop14-like family Mannosyl_trans3 PF11051.8 EGF81363.1 - 1.8e-46 158.7 0.0 3.1e-46 157.9 0.0 1.3 1 1 0 1 1 1 1 Mannosyltransferase putative Preseq_ALAS PF09029.10 EGF81364.1 - 0.24 11.9 11.5 2.6 8.5 0.1 3.8 1 1 0 2 2 2 0 5-aminolevulinate synthase presequence Cyto_heme_lyase PF01265.17 EGF81364.1 - 2 7.9 14.0 3.6 7.1 3.6 2.7 1 1 2 3 3 3 0 Cytochrome c/c1 heme lyase NotI PF12183.8 EGF81364.1 - 7.5 5.8 8.7 1.9 7.8 0.2 3.0 2 1 1 3 3 3 0 Restriction endonuclease NotI SSF PF00474.17 EGF81366.1 - 1.2e-06 27.6 27.0 1.2e-06 27.6 27.0 2.8 1 1 1 2 2 2 1 Sodium:solute symporter family Sulfate_transp PF00916.20 EGF81367.1 - 2.1e-90 303.2 20.5 2.9e-90 302.8 20.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGF81367.1 - 1.2e-21 76.5 0.3 7.5e-21 73.9 0.1 2.2 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 EGF81367.1 - 2.1e-05 24.9 2.9 2.1e-05 24.9 2.9 3.6 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily ARL2_Bind_BART PF11527.8 EGF81369.1 - 5.1e-28 97.5 2.2 7.5e-28 97.0 2.2 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Aminotran_4 PF01063.19 EGF81370.1 - 1.9e-23 83.5 0.0 2.3e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_M24 PF00557.24 EGF81371.1 - 6.5e-58 195.9 0.1 9.9e-58 195.3 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGF81371.1 - 4.1e-22 78.2 0.0 1.2e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain HhH-GPD PF00730.25 EGF81372.1 - 3.6e-20 72.4 0.0 5.9e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGF81372.1 - 2.6e-07 30.2 0.2 1.1e-06 28.1 0.0 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGF81372.1 - 0.0076 16.8 0.0 1.3 9.7 0.0 2.7 2 1 0 2 2 2 1 Helix-hairpin-helix domain DUF3693 PF12472.8 EGF81372.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Phage related protein EndIII_4Fe-2S PF10576.9 EGF81372.1 - 0.26 11.7 4.7 0.42 11.0 4.7 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III NOC3p PF07540.11 EGF81374.1 - 0.098 13.1 0.2 0.15 12.5 0.2 1.5 1 1 0 1 1 1 0 Nucleolar complex-associated protein MF_alpha_N PF05436.11 EGF81374.1 - 0.17 11.8 1.2 0.28 11.1 1.2 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF5054 PF16477.5 EGF81375.1 - 0.0046 16.8 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5054) IstB_IS21 PF01695.17 EGF81375.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GET2 PF08690.10 EGF81376.1 - 0.023 14.4 2.2 0.028 14.1 2.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1690 PF07956.11 EGF81376.1 - 0.42 11.0 6.8 0.81 10.1 3.3 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Asp PF00026.23 EGF81377.1 - 5.7e-14 52.3 0.0 1.8e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF81377.1 - 0.00059 19.6 0.0 0.0043 16.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal GPS2_interact PF15784.5 EGF81380.1 - 0.019 15.4 0.2 0.03 14.7 0.2 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DASH_Dad2 PF08654.10 EGF81380.1 - 0.11 12.9 1.2 1.1 9.7 0.4 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad2 DUF1275 PF06912.11 EGF81381.1 - 5.2e-17 62.4 10.1 1.7e-16 60.7 10.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EGF81381.1 - 0.04 13.8 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 PIG-P Serglycin PF04360.12 EGF81385.1 - 0.0031 17.5 2.5 0.061 13.3 0.1 2.5 2 0 0 2 2 2 1 Serglycin GPS2_interact PF15784.5 EGF81385.1 - 0.019 15.4 0.1 0.041 14.3 0.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DASH_Dad2 PF08654.10 EGF81385.1 - 0.071 13.5 2.9 0.19 12.1 0.2 2.7 3 1 0 3 3 3 0 DASH complex subunit Dad2 KRTAP PF11759.8 EGF81385.1 - 0.49 11.0 9.0 0.92 10.1 4.7 2.3 2 0 0 2 2 2 0 Keratin-associated matrix DUF1275 PF06912.11 EGF81386.1 - 3.4e-27 95.6 19.3 4.1e-27 95.3 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 EGF81386.1 - 0.094 12.6 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 PIG-P AAA_14 PF13173.6 EGF81390.1 - 0.00023 21.2 0.0 0.98 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Pkinase PF00069.25 EGF81391.1 - 2.7e-13 49.9 0.0 4.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81391.1 - 1.8e-07 30.7 0.0 2.2e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF81391.1 - 2.9e-05 23.5 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF81391.1 - 0.00054 20.0 0.0 0.0049 16.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF81391.1 - 0.006 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF81391.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DASH_Duo1 PF08651.10 EGF81392.1 - 0.51 10.1 3.0 0.51 10.2 1.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 AAA_22 PF13401.6 EGF81393.1 - 0.002 18.4 0.0 0.017 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF2642 PF10842.8 EGF81397.1 - 0.11 12.4 0.9 16 5.4 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2642) DUF4246 PF14033.6 EGF81398.1 - 1.5e-29 103.4 0.0 1.9e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DnaJ PF00226.31 EGF81400.1 - 6.2e-20 71.1 0.4 1.6e-19 69.8 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain TMA7 PF09072.10 EGF81400.1 - 3.3e-18 66.3 11.1 3.3e-18 66.3 11.1 2.9 3 0 0 3 3 3 1 Translation machinery associated TMA7 Sec63 PF02889.16 EGF81400.1 - 2.2e-17 63.1 3.1 8.3e-17 61.2 3.1 1.8 1 1 0 1 1 1 1 Sec63 Brl domain Antimicrobial10 PF08105.11 EGF81400.1 - 0.22 11.6 0.1 0.53 10.4 0.1 1.6 1 0 0 1 1 1 0 Metchnikowin family BRX PF08381.11 EGF81400.1 - 1.6 8.1 4.6 0.24 10.8 0.2 1.9 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Hira PF07569.11 EGF81401.1 - 6.6e-34 117.6 1.8 8.5e-22 78.0 0.0 3.1 2 1 1 3 3 3 2 TUP1-like enhancer of split WD40 PF00400.32 EGF81401.1 - 2e-23 82.2 10.5 1e-06 29.3 0.1 7.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81401.1 - 3e-12 46.7 0.1 0.015 15.6 0.0 5.4 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGF81401.1 - 4.7e-07 29.5 0.3 1.3e-06 28.1 0.3 1.8 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.11 EGF81401.1 - 7.3e-05 22.7 0.0 0.0059 16.5 0.0 3.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Mcl1_mid PF12341.8 EGF81401.1 - 0.0045 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region IKI3 PF04762.12 EGF81401.1 - 0.047 11.7 0.5 0.62 8.0 0.5 2.5 1 1 0 1 1 1 0 IKI3 family tRNA_synthFbeta PF17759.1 EGF81402.1 - 4.6e-48 163.5 0.0 6.6e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGF81402.1 - 9e-29 99.5 0.5 9e-28 96.3 0.2 2.6 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGF81402.1 - 1.8e-26 92.8 0.2 3.4e-26 92.0 0.2 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGF81402.1 - 5.4e-16 58.6 0.1 8.2e-14 51.7 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain T6PP_N PF18572.1 EGF81402.1 - 0.016 15.0 0.0 0.39 10.6 0.0 2.6 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain PDZ PF00595.24 EGF81404.1 - 0.11 12.8 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 PDZ domain DUF1394 PF07159.12 EGF81405.1 - 6.5e-105 350.7 0.0 7.5e-105 350.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF3159 PF11361.8 EGF81405.1 - 0.044 13.5 0.4 0.07 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Guanylate_cyc PF00211.20 EGF81406.1 - 2.2e-63 213.2 0.0 5.1e-63 212.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EGF81406.1 - 1.2e-12 47.9 0.1 4.1e-12 46.3 0.1 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGF81406.1 - 2.2e-12 47.0 6.3 1.6e-11 44.2 0.0 4.2 5 0 0 5 5 5 1 PAS fold HNOBA PF07701.14 EGF81406.1 - 1.4e-05 24.6 2.3 1.4e-05 24.6 2.3 3.5 3 1 0 3 3 3 1 Heme NO binding associated PAS_4 PF08448.10 EGF81406.1 - 0.00018 21.7 0.0 0.00046 20.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold Peptidase_S55 PF05580.12 EGF81406.1 - 0.0034 17.4 0.3 0.0034 17.4 0.3 2.7 3 0 0 3 3 3 1 SpoIVB peptidase S55 PAS_8 PF13188.7 EGF81406.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_10 PF13596.6 EGF81406.1 - 0.045 14.4 0.3 0.82 10.3 0.0 3.1 2 0 0 2 2 2 0 PAS domain RTX_C PF08339.10 EGF81406.1 - 3.2 7.8 9.6 1.3 9.1 4.5 2.8 2 1 1 3 3 3 0 RTX C-terminal domain DUF4097 PF13349.6 EGF81407.1 - 2.4e-07 30.4 1.7 2.4e-07 30.4 1.7 2.0 1 1 1 2 2 2 1 Putative adhesin Prominin PF05478.11 EGF81407.1 - 0.16 9.9 2.3 0.21 9.5 2.3 1.1 1 0 0 1 1 1 0 Prominin DUF1204 PF06721.11 EGF81407.1 - 0.19 11.1 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF996 PF06195.13 EGF81408.1 - 3.3 8.0 15.4 2.4 8.4 3.4 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF996) DUF974 PF06159.13 EGF81409.1 - 1.9e-69 234.2 0.1 3.8e-69 233.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 EGF81409.1 - 8.4e-05 22.1 1.4 0.0015 18.0 0.1 2.9 2 1 1 3 3 3 1 TRAPP trafficking subunit Trs65 TPR_11 PF13414.6 EGF81410.1 - 2.5e-05 23.8 0.9 0.14 11.9 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 EGF81410.1 - 4.3e-05 23.4 0.2 0.076 13.3 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF81410.1 - 7.9e-05 22.8 0.1 0.12 12.8 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81410.1 - 0.00027 21.4 0.1 0.12 12.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81410.1 - 0.0014 19.3 0.0 24 6.1 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF81410.1 - 0.0031 17.3 0.8 0.065 13.1 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF81410.1 - 0.0085 16.3 1.5 11 6.4 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGF81410.1 - 0.014 16.0 1.8 1.2 9.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF81410.1 - 0.037 14.1 1.1 3.9 7.8 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF81410.1 - 0.049 13.7 0.1 13 6.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81410.1 - 0.091 13.1 0.0 7.7 6.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF81410.1 - 0.17 12.0 0.2 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Myosin_tail_1 PF01576.19 EGF81411.1 - 2e-15 55.8 33.4 2.2e-15 55.6 33.4 1.0 1 0 0 1 1 1 1 Myosin tail DUF4407 PF14362.6 EGF81411.1 - 0.0074 15.7 15.4 0.0088 15.4 15.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 EGF81411.1 - 0.015 16.1 9.4 0.015 16.1 9.4 2.2 2 1 0 2 2 2 0 Occludin homology domain MbeD_MobD PF04899.12 EGF81411.1 - 0.016 15.3 5.2 0.21 11.7 0.6 2.7 2 1 1 3 3 3 0 MbeD/MobD like DASH_Dad4 PF08650.10 EGF81411.1 - 0.18 11.8 7.5 5 7.2 0.7 3.2 1 1 2 3 3 3 0 DASH complex subunit Dad4 Baculo_F PF12259.8 EGF81411.1 - 0.33 9.4 6.4 0.27 9.7 5.2 1.4 1 1 0 1 1 1 0 Baculovirus F protein Bestrophin PF01062.21 EGF81411.1 - 0.34 10.3 2.7 0.47 9.8 2.7 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Prominin PF05478.11 EGF81411.1 - 0.53 8.2 6.5 0.6 8.0 6.5 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 EGF81411.1 - 0.66 9.5 12.3 0.88 9.1 12.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 EGF81411.1 - 0.67 10.0 10.5 0.71 9.9 9.3 1.4 1 1 0 1 1 1 0 Helicase HerA, central domain HalX PF08663.10 EGF81411.1 - 0.72 10.2 17.6 2.4 8.6 3.0 3.3 2 2 0 2 2 2 0 HalX domain Spc7 PF08317.11 EGF81411.1 - 0.82 8.5 27.4 1.3 7.8 27.0 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EGF81411.1 - 0.86 9.6 31.0 1.2 9.2 23.1 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACCA PF03255.14 EGF81411.1 - 0.92 9.4 17.0 4.2 7.2 7.8 3.1 1 1 3 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Imm7 PF15585.6 EGF81411.1 - 1.3 9.3 3.7 1.9 8.8 0.9 2.5 1 1 2 3 3 3 0 Immunity protein 7 Fib_alpha PF08702.10 EGF81411.1 - 1.5 9.0 14.0 1.3 9.2 8.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 EGF81411.1 - 1.5 8.3 15.8 2 7.9 8.1 2.7 1 1 2 3 3 3 0 fzo-like conserved region FUSC PF04632.12 EGF81411.1 - 2.5 6.5 5.7 2.9 6.3 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2802 PF10975.8 EGF81411.1 - 3.2 7.9 11.6 0.63 10.2 1.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2802) APG6_N PF17675.1 EGF81411.1 - 3.7 8.1 31.0 2.4e+02 2.2 31.0 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Fez1 PF06818.15 EGF81411.1 - 4.6 7.6 26.4 2.7 8.4 21.9 1.7 1 1 0 1 1 1 0 Fez1 SlyX PF04102.12 EGF81411.1 - 4.9 7.9 15.2 0.94 10.1 5.6 3.0 1 1 1 2 2 2 0 SlyX DUF724 PF05266.14 EGF81411.1 - 7.9 6.3 23.1 2.7 7.8 15.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CCDC-167 PF15188.6 EGF81411.1 - 9.5 6.6 22.5 0.55 10.6 6.7 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 RINT1_TIP1 PF04437.13 EGF81412.1 - 2.3e-63 214.8 12.0 3.4e-42 145.0 9.8 3.0 2 1 1 3 3 3 3 RINT-1 / TIP-1 family DUF2470 PF10615.9 EGF81412.1 - 0.11 13.1 0.4 6.5 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2470) SHNi-TPR PF10516.9 EGF81413.1 - 0.032 13.7 0.0 0.091 12.2 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR TPR_2 PF07719.17 EGF81413.1 - 0.08 13.1 6.8 1.1 9.5 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF81413.1 - 0.083 12.7 0.6 11 6.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 EGF81413.1 - 0.12 12.2 3.7 0.7 9.8 0.2 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_7 PF13176.6 EGF81413.1 - 0.12 12.4 6.8 0.37 10.9 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81413.1 - 0.56 10.5 8.1 13 6.1 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-MYND PF01753.18 EGF81413.1 - 1.6 8.9 21.4 0.13 12.4 14.8 2.3 2 0 0 2 2 2 0 MYND finger Rad21_Rec8_N PF04825.13 EGF81414.1 - 9.8e-36 122.3 0.3 1.8e-35 121.4 0.3 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGF81414.1 - 4.2e-13 48.4 0.1 1.3e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 EGF81414.1 - 0.091 12.7 3.7 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Segregation and condensation protein ScpA Got1 PF04178.12 EGF81415.1 - 1.6e-16 60.7 14.7 1.6e-16 60.7 14.7 1.4 2 0 0 2 2 2 1 Got1/Sft2-like family DUF308 PF03729.13 EGF81415.1 - 0.0042 17.4 14.5 0.0042 17.4 14.5 2.1 1 1 1 2 2 2 1 Short repeat of unknown function (DUF308) DUF1129 PF06570.11 EGF81415.1 - 4.1 6.9 7.5 5.1 6.5 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) SPT16 PF08644.11 EGF81416.1 - 7.6e-54 182.0 0.3 3e-53 180.1 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EGF81416.1 - 9.5e-46 155.5 0.2 2.4e-45 154.3 0.1 1.8 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGF81416.1 - 1e-28 100.5 0.0 1.9e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGF81416.1 - 1.6e-14 54.1 0.1 3.8e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 EGF81416.1 - 0.059 13.6 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) RNase_PH PF01138.21 EGF81417.1 - 3.5e-26 92.3 0.1 4.7e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 VHS PF00790.19 EGF81418.1 - 2.7e-41 140.7 0.0 5.5e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.20 EGF81418.1 - 8.2e-22 77.6 0.2 1.8e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 EGF81418.1 - 4.7e-17 62.0 1.8 1.6e-16 60.4 0.8 2.4 2 0 0 2 2 2 1 GAT domain Ras PF00071.22 EGF81419.1 - 9e-34 116.4 0.1 1.2e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF81419.1 - 1.4e-24 86.6 0.0 2.6e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF81419.1 - 1.3e-07 31.2 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGF81419.1 - 6.3e-07 29.0 0.1 9.1e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGF81419.1 - 0.00096 18.1 0.1 0.26 10.1 0.0 2.1 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EGF81419.1 - 0.0091 15.2 0.4 0.076 12.2 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit TniB PF05621.11 EGF81419.1 - 0.039 13.4 0.0 1.9 7.9 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein Spermine_synth PF01564.17 EGF81420.1 - 5.2e-06 26.0 0.0 8.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain P5-ATPase PF12409.8 EGF81420.1 - 0.0021 18.1 1.4 0.0021 18.1 1.4 1.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter Methyltransf_25 PF13649.6 EGF81420.1 - 0.046 14.4 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 EGF81420.1 - 0.099 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 EGF81420.1 - 0.15 12.7 0.0 0.43 11.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain EMP70 PF02990.16 EGF81421.1 - 1.8e-201 670.4 15.8 2.5e-201 669.9 15.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ApbA_C PF08546.11 EGF81422.1 - 1.5e-28 99.5 0.0 2.5e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGF81422.1 - 1.3e-20 73.6 0.3 2.7e-20 72.5 0.2 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TPR_1 PF00515.28 EGF81423.1 - 2.9e-14 52.2 4.0 2.1e-07 30.4 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF81423.1 - 5.7e-10 38.5 0.4 0.00034 20.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81423.1 - 3e-08 33.2 4.1 0.0013 18.8 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81423.1 - 1.5e-07 31.8 0.0 3.9e-05 24.1 0.0 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF81423.1 - 8.4e-06 25.9 0.6 0.00016 21.8 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EGF81423.1 - 1e-05 25.5 0.4 0.0021 18.1 0.0 3.0 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EGF81423.1 - 4e-05 24.0 0.1 1.4 9.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGF81423.1 - 7e-05 22.8 1.1 0.0028 17.6 0.3 2.3 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_12 PF13424.6 EGF81423.1 - 0.00061 20.0 0.1 0.0086 16.3 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF81423.1 - 0.00076 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGF81423.1 - 0.015 15.0 1.5 0.51 10.1 0.0 3.5 3 1 1 4 4 4 0 TPR repeat TPR_7 PF13176.6 EGF81423.1 - 0.016 15.2 0.6 0.033 14.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81423.1 - 0.036 14.9 0.0 8.7 7.5 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF81423.1 - 0.053 13.9 5.7 0.8 10.2 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.23 EGF81424.1 - 7.6e-24 83.5 0.0 1.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGF81424.1 - 7.2e-18 64.7 0.1 2.1e-17 63.2 0.1 1.7 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGF81424.1 - 0.0062 16.6 0.2 0.021 14.9 0.2 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC3 PF18771.1 EGF81424.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 APOBEC3 Inv-AAD PF18785.1 EGF81424.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Band_7 PF01145.25 EGF81425.1 - 6e-14 52.4 0.1 6e-14 52.4 0.1 2.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family BTB_2 PF02214.22 EGF81426.1 - 9.6e-09 35.5 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Aminotran_1_2 PF00155.21 EGF81428.1 - 4.8e-81 272.7 0.0 6e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGF81428.1 - 2.8e-05 23.5 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGF81428.1 - 3.6e-05 22.5 0.0 5.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGF81428.1 - 7e-05 21.9 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.10 EGF81428.1 - 0.0095 16.4 6.8 0.08 13.4 6.8 2.4 1 1 0 1 1 1 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 EGF81428.1 - 0.014 14.7 0.2 0.027 13.8 0.2 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ANF_receptor PF01094.28 EGF81429.1 - 1.6e-26 93.3 0.2 2.8e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 EGF81429.1 - 2.3e-21 76.6 22.9 4.3e-21 75.7 22.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR FHA PF00498.26 EGF81430.1 - 9.2e-15 54.8 0.0 2.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EGF81430.1 - 6.2e-11 41.8 8.6 1.1e-10 41.1 8.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGF81430.1 - 2.7e-08 34.0 10.1 4.2e-08 33.4 10.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGF81430.1 - 0.00018 21.4 8.9 0.00029 20.7 8.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGF81430.1 - 0.00082 19.4 3.8 0.0017 18.4 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGF81430.1 - 0.0036 17.1 10.1 0.0057 16.5 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 EGF81430.1 - 0.0055 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 EGF81430.1 - 0.0055 17.0 7.3 0.012 15.9 7.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF81430.1 - 0.053 13.4 13.1 0.089 12.7 13.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF81430.1 - 0.054 13.4 8.2 0.083 12.8 8.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF81430.1 - 0.058 13.4 11.6 0.12 12.5 11.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 EGF81430.1 - 0.083 12.8 6.6 0.14 12.1 6.6 1.4 1 0 0 1 1 1 0 PHD-finger Nuc_deoxyri_tr3 PF11071.8 EGF81430.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Cupin_8 PF13621.6 EGF81431.1 - 1.4e-37 129.8 0.0 2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGF81431.1 - 3.6e-08 33.2 0.1 7.1e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGF81431.1 - 0.0033 17.8 0.1 0.009 16.4 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGF81431.1 - 0.075 12.8 0.1 0.55 10.0 0.0 2.3 3 0 0 3 3 3 0 Cupin domain DUF4596 PF15363.6 EGF81433.1 - 4.3 7.7 10.8 10 6.5 0.2 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) Mito_carr PF00153.27 EGF81434.1 - 5.2e-66 218.6 0.8 1.4e-24 85.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2499 PF10693.9 EGF81434.1 - 0.071 13.4 0.2 4.8 7.5 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2499) zf-C2H2 PF00096.26 EGF81436.1 - 1.2e-08 35.0 29.1 3.2e-06 27.3 2.1 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF81436.1 - 1.4e-05 25.5 26.2 0.0058 17.4 1.3 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGF81436.1 - 0.002 18.1 0.4 0.002 18.1 0.4 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 EGF81436.1 - 0.0061 16.9 17.5 0.044 14.2 1.0 4.0 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGF81436.1 - 0.023 15.0 13.7 0.21 11.9 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding R3H PF01424.22 EGF81436.1 - 0.089 12.8 2.7 1.6 8.7 1.6 2.7 2 0 0 2 2 2 0 R3H domain Mut7-C PF01927.16 EGF81436.1 - 0.11 12.6 2.9 0.13 12.4 1.4 1.9 1 1 0 1 1 1 0 Mut7-C RNAse domain zf-CCHC_2 PF13696.6 EGF81436.1 - 9.3 6.2 11.3 3.5 7.6 0.9 3.7 3 0 0 3 3 3 0 Zinc knuckle ABC_tran PF00005.27 EGF81437.1 - 4.3e-17 62.9 0.0 1.5e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF81437.1 - 1.4e-10 41.4 2.0 0.00029 20.8 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF81437.1 - 0.00021 21.0 0.2 0.00046 19.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGF81437.1 - 0.00089 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGF81437.1 - 0.0011 18.7 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGF81437.1 - 0.0016 18.9 0.2 0.0026 18.3 0.2 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF81437.1 - 0.0018 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGF81437.1 - 0.0037 17.7 0.2 0.006 17.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGF81437.1 - 0.012 15.1 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EGF81437.1 - 0.02 15.1 0.1 0.041 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF81437.1 - 0.023 15.0 0.6 0.088 13.1 0.6 2.0 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EGF81437.1 - 0.035 11.7 0.4 0.049 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 EGF81437.1 - 0.049 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EGF81437.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGF81437.1 - 0.086 12.4 0.4 1.9 8.1 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGF81437.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EGF81437.1 - 0.097 13.2 0.1 0.24 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EGF81437.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGF81437.1 - 0.13 12.2 0.6 1.3 9.0 0.1 2.5 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Arf PF00025.21 EGF81437.1 - 0.13 11.7 0.4 0.28 10.6 0.4 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_7 PF12775.7 EGF81437.1 - 0.24 10.9 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 EGF81438.1 - 1.9e-44 151.2 0.0 2.3e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF81438.1 - 8.5e-22 77.6 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF81438.1 - 1.5e-09 37.6 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 EGF81438.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FERM_M PF00373.18 EGF81441.1 - 5.8e-14 52.5 0.0 1.3e-13 51.4 0.0 1.6 2 0 0 2 2 2 1 FERM central domain Nucleoporin_FG2 PF15967.5 EGF81441.1 - 0.12 10.9 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Gar1 PF04410.14 EGF81442.1 - 6.7e-37 126.6 0.0 7.8e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MMM1 PF10296.9 EGF81443.1 - 1.4e-61 208.4 3.9 3.2e-59 200.7 3.9 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 AAA_16 PF13191.6 EGF81444.1 - 0.0011 19.4 0.0 0.0034 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.17 EGF81444.1 - 0.021 14.9 7.7 0.99 9.7 1.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81444.1 - 0.063 13.6 0.1 19 5.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGF81444.1 - 0.13 12.4 0.7 0.85 9.8 0.1 2.6 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Guanylate_cyc PF00211.20 EGF81445.1 - 1.5e-16 60.6 0.0 3.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Transposase_mut PF00872.18 EGF81445.1 - 0.0093 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family AAA_16 PF13191.6 EGF81445.1 - 0.094 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf_C2H2_ZHX PF18387.1 EGF81445.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2613 PF11021.8 EGF81446.1 - 0.016 15.3 0.4 0.047 13.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) ATPase_gene1 PF09527.10 EGF81446.1 - 1.9 8.7 8.0 4.6 7.5 3.5 2.5 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Clat_adaptor_s PF01217.20 EGF81447.1 - 6.9e-22 77.9 0.2 9.7e-22 77.4 0.2 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain PI_PP_C PF18365.1 EGF81448.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain TMEM208_SND2 PF05620.11 EGF81449.1 - 5.3e-28 97.9 7.3 9.4e-28 97.1 7.3 1.3 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Fasciclin PF02469.22 EGF81450.1 - 1.9e-05 24.9 1.5 0.0011 19.2 0.0 2.5 2 1 0 2 2 2 2 Fasciclin domain Beta_elim_lyase PF01212.21 EGF81451.1 - 4.1e-79 265.9 0.0 5.2e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGF81451.1 - 5.6e-05 22.5 0.0 0.00013 21.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGF81451.1 - 0.0003 19.5 0.0 0.0009 17.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 EGF81451.1 - 0.00033 19.4 0.0 0.00056 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EGF81451.1 - 0.0048 16.3 0.2 0.017 14.5 0.2 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family bZIP_1 PF00170.21 EGF81452.1 - 7.6e-09 35.5 15.2 1.5e-06 28.2 7.1 2.8 2 1 0 2 2 2 2 bZIP transcription factor GIT_CC PF16559.5 EGF81452.1 - 0.0008 19.2 5.9 0.0021 17.9 5.9 1.7 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 EGF81452.1 - 0.014 15.5 6.6 0.014 15.5 6.6 2.3 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 EGF81452.1 - 0.53 10.4 19.1 0.32 11.1 7.1 2.9 2 1 1 3 3 3 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 EGF81452.1 - 0.54 10.8 11.7 3.8 8.1 0.0 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF349 PF03993.12 EGF81452.1 - 1.5 9.2 8.7 1.1 9.6 1.7 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) V_ATPase_I PF01496.19 EGF81452.1 - 2.7 5.8 7.9 3.9 5.3 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAPEG PF01124.18 EGF81453.1 - 1.7e-21 76.5 0.7 2e-21 76.2 0.7 1.1 1 0 0 1 1 1 1 MAPEG family Cullin PF00888.22 EGF81454.1 - 1.7e-188 628.1 18.9 2.2e-188 627.7 18.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGF81454.1 - 9.2e-20 70.5 0.7 9.2e-20 70.5 0.7 3.2 4 0 0 4 4 4 1 Cullin protein neddylation domain zf-RING_14 PF17978.1 EGF81454.1 - 0.049 14.1 0.2 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TetR_C_8 PF14278.6 EGF81454.1 - 0.14 12.3 2.5 1.3 9.2 0.1 3.2 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Ferritin PF00210.24 EGF81454.1 - 0.32 10.9 3.5 0.37 10.7 1.2 2.1 2 0 0 2 2 2 0 Ferritin-like domain YjeF_N PF03853.15 EGF81455.1 - 5.6e-12 45.9 0.1 7.5e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus DnaJ_CXXCXGXG PF00684.19 EGF81456.1 - 8.3e-08 32.5 48.6 0.00063 20.1 8.6 6.1 2 2 4 6 6 6 5 DnaJ central domain Peptidase_M48 PF01435.18 EGF81457.1 - 6.1e-37 127.3 0.0 9.1e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 EGF81457.1 - 0.075 12.6 0.4 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Kelch_2 PF07646.15 EGF81457.1 - 0.19 11.8 0.1 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Presenilin PF01080.17 EGF81458.1 - 8.7e-68 228.9 14.3 4e-38 131.2 5.2 2.0 1 1 1 2 2 2 2 Presenilin Adeno_E3_CR2 PF02439.15 EGF81458.1 - 1.4 8.7 4.1 0.89 9.4 0.4 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Arm PF00514.23 EGF81459.1 - 8e-13 47.9 7.7 0.00068 19.6 0.2 6.3 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGF81459.1 - 9.7e-13 48.3 2.8 2.5e-07 31.0 1.3 4.1 2 2 1 3 3 3 3 HEAT repeats RTP1_C1 PF10363.9 EGF81459.1 - 3.8e-06 27.1 1.6 0.0057 16.8 0.1 3.4 2 2 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EGF81459.1 - 4.4e-06 26.5 12.5 0.035 14.3 0.2 6.3 5 2 1 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EGF81459.1 - 0.00017 22.0 9.6 0.093 13.3 1.2 5.2 4 2 1 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 EGF81459.1 - 0.00056 18.6 10.2 0.0013 17.4 4.5 3.0 1 1 1 2 2 2 1 Adaptin N terminal region MMS19_N PF14500.6 EGF81459.1 - 0.0019 17.8 0.7 0.18 11.3 0.0 2.7 1 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_PBS PF03130.16 EGF81459.1 - 0.014 16.0 0.3 0.14 12.9 0.2 2.9 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat RasGEF_N_2 PF14663.6 EGF81459.1 - 0.016 15.6 1.5 6.1 7.3 0.1 3.1 3 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 EGF81459.1 - 0.061 13.9 0.6 10 6.8 0.1 3.2 2 2 1 3 3 3 0 Vacuolar 14 Fab1-binding region RYDR_ITPR PF01365.21 EGF81459.1 - 0.27 10.6 3.4 2 7.8 0.0 2.9 2 1 0 2 2 2 0 RIH domain TruD PF01142.18 EGF81460.1 - 1.2e-70 238.5 0.0 5.3e-69 233.0 0.0 2.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Trypan_PARP PF05887.11 EGF81460.1 - 0.028 14.4 14.1 0.056 13.4 14.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RhoGAP PF00620.27 EGF81461.1 - 3.7e-11 43.1 0.0 7.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 EGF81461.1 - 0.054 13.7 0.7 0.12 12.6 0.7 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif DS PF01916.17 EGF81462.1 - 1.1e-133 444.9 0.0 1.3e-133 444.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase IKI3 PF04762.12 EGF81463.1 - 2.6e-267 889.5 3.8 4.2e-267 888.8 3.8 1.3 1 0 0 1 1 1 1 IKI3 family TPR_14 PF13428.6 EGF81463.1 - 0.036 14.9 0.3 0.24 12.3 0.3 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Clathrin PF00637.20 EGF81463.1 - 0.21 11.5 3.3 3.1 7.7 0.5 3.6 2 1 1 3 3 3 0 Region in Clathrin and VPS Aldolase_II PF00596.21 EGF81465.1 - 2.1e-43 148.4 0.0 2.6e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ribosomal_S7 PF00177.21 EGF81467.1 - 1.7e-37 128.4 0.8 2.1e-37 128.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e BK_channel_a PF03493.18 EGF81468.1 - 3.6e-21 75.2 0.6 1.3e-20 73.4 0.3 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit F-box-like PF12937.7 EGF81468.1 - 8.2e-05 22.4 0.3 0.0002 21.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF81468.1 - 0.0034 17.2 0.2 0.014 15.3 0.2 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EGF81468.1 - 0.031 14.7 2.2 6.5 7.3 0.0 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) TrkA_N PF02254.18 EGF81468.1 - 0.06 13.6 0.0 0.42 10.9 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain WD40 PF00400.32 EGF81469.1 - 2.8e-07 31.1 12.9 0.17 12.8 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Dip PF17679.1 EGF81469.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 gp37/Dip protein Acetyltransf_3 PF13302.7 EGF81470.1 - 3.9e-09 37.3 0.0 4.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF81470.1 - 0.006 16.8 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF4436 PF14494.6 EGF81471.1 - 3.5e-31 108.4 2.6 3.5e-31 108.4 2.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4436) ABC2_membrane_5 PF13346.6 EGF81471.1 - 0.0015 18.1 9.6 0.0021 17.6 5.5 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein MPS-4 PF17523.2 EGF81471.1 - 1.7 8.9 6.7 2.8 8.1 1.2 2.8 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Sigma_reg_N PF13800.6 EGF81471.1 - 3.4 8.0 8.1 1.2 9.5 1.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal SurA_N_3 PF13624.6 EGF81471.1 - 6.3 6.6 6.8 0.19 11.5 0.3 1.8 2 0 0 2 2 2 0 SurA N-terminal domain SurA_N_2 PF13623.6 EGF81471.1 - 6.4 6.6 6.6 0.28 11.0 0.3 1.9 2 0 0 2 2 2 0 SurA N-terminal domain ABC_tran PF00005.27 EGF81472.1 - 5.4e-43 146.8 2.2 5e-21 75.7 0.0 4.2 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EGF81472.1 - 5.2e-23 82.3 2.1 6.6e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGF81472.1 - 4.5e-12 45.9 2.0 0.1 12.0 0.0 4.4 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EGF81472.1 - 4.6e-11 42.6 2.8 4.6e-11 42.6 2.8 1.8 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.6 EGF81472.1 - 3.9e-08 33.7 1.9 0.0011 19.3 0.0 4.4 2 2 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EGF81472.1 - 4.1e-08 34.0 3.4 0.00082 19.9 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGF81472.1 - 1e-06 28.4 0.7 0.024 14.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGF81472.1 - 1.1e-06 28.6 1.7 0.004 16.9 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EGF81472.1 - 1.2e-06 28.4 2.1 0.035 13.9 0.0 3.8 2 2 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EGF81472.1 - 2.2e-06 27.7 0.9 0.08 12.8 0.1 3.9 4 0 0 4 4 3 2 RsgA GTPase AAA_28 PF13521.6 EGF81472.1 - 9.6e-06 25.9 0.1 0.014 15.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGF81472.1 - 1.7e-05 25.3 0.0 0.027 14.9 0.0 3.5 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGF81472.1 - 6e-05 23.0 0.0 0.06 13.3 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 EGF81472.1 - 0.00011 22.3 0.0 0.21 11.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 EGF81472.1 - 0.00024 21.2 2.0 0.67 10.1 0.3 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGF81472.1 - 0.00025 21.4 0.0 0.2 12.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 EGF81472.1 - 0.00029 21.2 4.5 0.06 13.7 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 EGF81472.1 - 0.00071 18.8 3.7 0.32 10.2 0.0 3.7 5 0 0 5 5 3 1 NB-ARC domain SbcCD_C PF13558.6 EGF81472.1 - 0.00092 19.4 0.1 0.91 9.8 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EGF81472.1 - 0.001 18.7 3.8 0.16 11.5 0.3 3.6 4 1 0 4 4 3 1 AAA domain AAA_5 PF07728.14 EGF81472.1 - 0.0031 17.5 3.0 1.3 9.0 0.0 3.8 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGF81472.1 - 0.0033 17.0 2.5 0.77 9.2 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 EGF81472.1 - 0.0088 15.8 10.5 1.4 8.6 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_18 PF13238.6 EGF81472.1 - 0.009 16.6 1.9 0.27 11.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 EGF81472.1 - 0.011 16.0 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EGF81472.1 - 0.013 15.3 0.0 0.28 10.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EGF81472.1 - 0.013 15.3 2.5 4.2 7.1 0.0 3.8 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGF81472.1 - 0.013 15.2 4.2 0.82 9.3 0.0 3.6 5 0 0 5 5 3 0 AAA domain ATPase_2 PF01637.18 EGF81472.1 - 0.014 15.3 1.5 0.077 12.9 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 EGF81472.1 - 0.015 15.0 0.4 0.046 13.4 0.1 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 EGF81472.1 - 0.018 13.8 0.0 1.1 8.0 0.1 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 EGF81472.1 - 0.019 14.9 2.1 1.9 8.4 0.0 3.6 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 EGF81472.1 - 0.021 15.0 4.4 1.3 9.2 0.0 3.3 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 EGF81472.1 - 0.024 14.3 1.3 0.63 9.6 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EGF81472.1 - 0.024 14.7 0.3 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Dynamin family Rad17 PF03215.15 EGF81472.1 - 0.042 13.8 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_27 PF13514.6 EGF81472.1 - 0.046 13.3 1.5 9.3 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain MobB PF03205.14 EGF81472.1 - 0.054 13.4 0.1 4.5 7.2 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 EGF81472.1 - 0.11 12.0 0.0 2.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 EGF81472.1 - 0.11 12.5 0.4 4.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 EGF81472.1 - 0.14 11.7 0.5 1.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B UDPG_MGDP_dh_C PF03720.15 EGF81472.1 - 0.14 12.6 0.0 0.48 10.9 0.0 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AAA_13 PF13166.6 EGF81472.1 - 0.16 10.6 5.0 0.57 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF1053 PF06327.14 EGF81472.1 - 0.25 11.9 0.9 0.67 10.5 0.9 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) PTS_IIB PF02302.17 EGF81472.1 - 1.1 10.0 3.0 12 6.7 0.1 3.6 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit SRP54 PF00448.22 EGF81472.1 - 1.5 8.4 7.3 2.3 7.8 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Guanylate_kin PF00625.21 EGF81473.1 - 3.3e-54 183.3 0.0 4.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EGF81473.1 - 3.2e-10 40.3 0.0 6.5e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF81473.1 - 4e-07 30.6 0.0 1.5e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGF81473.1 - 5.2e-07 30.3 0.0 1.1e-06 29.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF81473.1 - 2.8e-06 27.7 0.0 1e-05 25.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGF81473.1 - 0.00013 22.5 0.0 0.00015 22.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EGF81473.1 - 0.00058 19.8 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGF81473.1 - 0.00065 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase CPT PF07931.12 EGF81473.1 - 0.0013 18.6 0.0 0.0066 16.3 0.0 1.9 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 EGF81473.1 - 0.0022 17.7 0.0 0.0071 16.1 0.0 1.9 2 0 0 2 2 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGF81473.1 - 0.0023 18.3 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EGF81473.1 - 0.0032 17.0 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EGF81473.1 - 0.0036 17.4 0.0 0.0081 16.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EGF81473.1 - 0.0037 16.6 0.0 0.047 12.9 0.0 2.0 1 1 0 1 1 1 1 KAP family P-loop domain ATPase_2 PF01637.18 EGF81473.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 EGF81473.1 - 0.0061 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein NACHT PF05729.12 EGF81473.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.17 EGF81473.1 - 0.0068 16.1 0.0 0.018 14.7 0.0 1.6 1 1 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EGF81473.1 - 0.007 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 EGF81473.1 - 0.0076 16.7 0.1 0.032 14.7 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGF81473.1 - 0.01 15.1 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 EGF81473.1 - 0.017 15.2 0.0 0.029 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGF81473.1 - 0.02 13.9 0.0 0.049 12.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EGF81473.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EGF81473.1 - 0.026 14.8 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EGF81473.1 - 0.027 14.3 0.0 0.92 9.3 0.0 2.2 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 EGF81473.1 - 0.03 14.8 0.1 0.31 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGF81473.1 - 0.031 14.1 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 EGF81473.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGF81473.1 - 0.036 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EGF81473.1 - 0.045 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EGF81473.1 - 0.051 13.5 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 NTPase G-alpha PF00503.20 EGF81473.1 - 0.051 12.7 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.6 EGF81473.1 - 0.058 13.9 0.1 0.17 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 EGF81473.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YqgF PF14639.6 EGF81473.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 NB-ARC PF00931.22 EGF81473.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 EGF81473.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EGF81473.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase DUF2075 PF09848.9 EGF81473.1 - 0.11 11.7 0.0 2.8 7.1 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.18 EGF81473.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin PRK PF00485.18 EGF81473.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.12 EGF81473.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PP2C PF00481.21 EGF81474.1 - 3.3e-34 118.7 0.0 1.1e-32 113.6 0.0 2.1 1 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGF81474.1 - 0.12 12.0 0.0 0.6 9.7 0.0 1.9 1 1 0 1 1 1 0 Protein phosphatase 2C CN_hydrolase PF00795.22 EGF81475.1 - 4.3e-63 213.1 0.0 4.9e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Proteasome_A_N PF10584.9 EGF81475.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Adeno_IVa2 PF02456.15 EGF81475.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein SEA PF01390.20 EGF81475.1 - 0.15 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 SEA domain Ras PF00071.22 EGF81476.1 - 2.5e-10 40.2 0.0 3.1e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 EGF81476.1 - 0.0019 17.7 0.0 0.0058 16.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EGF81476.1 - 0.002 18.3 0.0 3.1 8.0 0.0 3.0 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGF81476.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.21 EGF81476.1 - 0.0097 15.4 0.3 7.1 6.0 0.1 2.8 2 1 1 3 3 3 2 ADP-ribosylation factor family AAA_22 PF13401.6 EGF81476.1 - 0.018 15.3 0.2 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGF81476.1 - 0.047 13.8 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.18 EGF81476.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.29 EGF81476.1 - 0.16 12.4 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mannosyl_trans3 PF11051.8 EGF81477.1 - 2.8e-46 158.1 0.0 5.9e-46 157.0 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative Gly_transf_sug PF04488.15 EGF81478.1 - 6.3e-15 55.6 0.1 1.7e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.11 EGF81479.1 - 0.00029 20.8 71.7 0.32 11.0 23.8 3.8 2 1 2 4 4 4 2 Procyclic acidic repetitive protein (PARP) DUF3381 PF11861.8 EGF81479.1 - 1.3 8.8 8.7 1.9 8.2 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CAP PF00188.26 EGF81480.1 - 1.6e-16 61.2 4.2 5e-16 59.7 4.2 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family ECH_1 PF00378.20 EGF81481.1 - 5.8e-84 281.3 2.2 6.6e-84 281.1 2.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGF81481.1 - 2.7e-34 119.1 5.2 6.9e-33 114.5 2.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGF81481.1 - 0.014 15.4 2.5 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Peptidase family S49 SBP_bac_11 PF13531.6 EGF81481.1 - 0.032 14.0 0.5 0.056 13.2 0.1 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Aldedh PF00171.22 EGF81482.1 - 2.7e-13 49.3 4.9 2.2e-07 29.7 2.5 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family SMC_N PF02463.19 EGF81483.1 - 8.4e-24 84.2 15.2 9.8e-23 80.7 15.2 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGF81483.1 - 1.6e-18 68.0 0.3 1.6e-18 68.0 0.3 4.6 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 EGF81483.1 - 5.3e-12 46.1 0.0 5.3e-12 46.1 0.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGF81483.1 - 1.8e-06 28.0 8.4 0.0016 18.3 0.1 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF81483.1 - 9.3e-05 22.1 0.1 0.00019 21.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TraF_2 PF13729.6 EGF81483.1 - 0.031 13.7 11.7 0.62 9.4 3.7 3.8 4 1 0 4 4 4 0 F plasmid transfer operon, TraF, protein SbcCD_C PF13558.6 EGF81483.1 - 0.069 13.4 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 EGF81483.1 - 0.16 11.5 2.4 2.5 7.7 0.1 3.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3896 PF13035.6 EGF81483.1 - 0.4 10.9 2.5 1.6 8.9 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Glyco_transf_22 PF03901.17 EGF81485.1 - 1.8e-86 291.0 8.9 2.3e-80 270.9 5.1 2.2 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EGF81485.1 - 0.039 14.2 12.2 0.099 12.9 12.2 1.7 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3275 PF11679.8 EGF81486.1 - 0.12 12.4 1.6 0.22 11.5 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) LptF_LptG PF03739.14 EGF81486.1 - 0.44 9.3 0.8 0.72 8.6 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Adaptin_binding PF10199.9 EGF81486.1 - 2.2 8.9 10.4 15 6.2 10.4 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 IGPD PF00475.18 EGF81489.1 - 3.8e-57 192.6 0.4 5.3e-57 192.2 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase GST_C_3 PF14497.6 EGF81490.1 - 1.8e-15 56.9 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGF81490.1 - 9e-07 29.1 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGF81490.1 - 7.2e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGF81490.1 - 0.0006 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGF81490.1 - 0.0089 16.0 0.1 0.02 14.9 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGF81490.1 - 0.037 14.3 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 EGF81490.1 - 0.062 13.5 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGF81490.1 - 0.066 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DHR10 PF18595.1 EGF81491.1 - 0.015 15.4 4.9 0.088 12.9 0.5 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF2203 PF09969.9 EGF81491.1 - 0.053 14.2 1.0 0.11 13.2 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PHM7_cyt PF14703.6 EGF81491.1 - 0.081 13.1 3.1 0.16 12.2 3.1 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1140 PF06600.11 EGF81491.1 - 0.13 12.7 1.3 0.35 11.3 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1140) FapA PF03961.13 EGF81491.1 - 0.39 9.3 3.8 0.52 8.9 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pex14_N PF04695.13 EGF81491.1 - 4 8.1 17.0 1.8 9.2 13.9 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RP-C_C PF11800.8 EGF81491.1 - 7.3 6.6 8.4 10 6.1 3.9 2.3 2 1 0 2 2 2 0 Replication protein C C-terminal region TMF_TATA_bd PF12325.8 EGF81492.1 - 0.001 19.3 7.2 0.0019 18.4 7.2 1.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EGF81492.1 - 0.0013 17.7 4.8 0.0015 17.5 4.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Phage_tail_APC PF16778.5 EGF81492.1 - 0.0023 17.8 0.2 0.031 14.1 0.0 2.1 2 0 0 2 2 2 1 Phage tail assembly chaperone protein EzrA PF06160.12 EGF81492.1 - 0.036 12.2 2.5 0.044 11.9 2.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 EGF81492.1 - 0.059 13.4 3.6 0.081 12.9 3.6 1.2 1 0 0 1 1 1 0 Laminin Domain II PCRF PF03462.18 EGF81492.1 - 0.12 12.2 2.3 0.15 11.9 2.3 1.1 1 0 0 1 1 1 0 PCRF domain T2SSF PF00482.23 EGF81492.1 - 0.13 12.3 1.9 0.16 11.9 1.9 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F XhlA PF10779.9 EGF81492.1 - 0.41 10.9 2.6 0.45 10.7 0.4 1.9 1 1 0 2 2 2 0 Haemolysin XhlA DUF4404 PF14357.6 EGF81492.1 - 3.3 8.4 11.0 4.8 7.9 4.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2431 PF10354.9 EGF81493.1 - 1.1e-25 90.8 0.0 3.3e-25 89.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) zf-C2H2_4 PF13894.6 EGF81493.1 - 0.00034 21.2 30.9 0.094 13.6 0.3 6.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF81493.1 - 0.00094 19.5 12.1 0.27 11.7 0.1 5.2 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGF81493.1 - 0.0031 17.9 0.4 0.0031 17.9 0.4 5.1 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGF81493.1 - 0.014 15.7 10.0 0.097 13.0 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2441 PF10386.9 EGF81493.1 - 0.18 11.8 0.5 0.33 10.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) zf-C2H2_2 PF12756.7 EGF81493.1 - 0.24 11.7 11.8 6 7.3 2.5 4.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Usp PF00582.26 EGF81494.1 - 7.3e-22 78.4 0.1 1e-21 77.9 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family Synaptobrevin PF00957.21 EGF81495.1 - 3e-19 68.6 1.2 3.2e-19 68.5 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.8 EGF81495.1 - 0.026 14.3 0.1 0.028 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PEMT PF04191.13 EGF81496.1 - 5.3e-36 123.2 14.9 3.1e-18 66.1 1.2 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase SSrecog PF03531.14 EGF81497.1 - 0.21 11.5 0.3 7.1 6.6 0.0 3.1 3 0 0 3 3 3 0 Structure-specific recognition protein (SSRP1) Tim54 PF11711.8 EGF81498.1 - 3.6e-43 147.8 0.0 1.5e-41 142.5 0.0 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 IGR PF09597.10 EGF81499.1 - 3.5e-23 81.4 1.5 8.5e-23 80.2 0.1 2.1 2 0 0 2 2 2 1 IGR protein motif SAM_1 PF00536.30 EGF81499.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_S6e PF01092.19 EGF81500.1 - 4.6e-58 194.6 1.3 5.6e-58 194.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Usp PF00582.26 EGF81501.1 - 8e-30 104.2 0.1 1.2e-29 103.6 0.1 1.3 1 0 0 1 1 1 1 Universal stress protein family PGM_PMM_I PF02878.16 EGF81501.1 - 0.055 13.2 0.0 0.25 11.1 0.0 1.9 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Filament PF00038.21 EGF81502.1 - 1.9e-05 24.4 2.8 2.2e-05 24.2 2.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein MscS_porin PF12795.7 EGF81502.1 - 0.0012 18.4 1.2 0.0022 17.6 1.2 1.4 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain IFT57 PF10498.9 EGF81502.1 - 0.0024 16.9 3.7 0.0028 16.7 3.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4810 PF16068.5 EGF81502.1 - 0.0026 18.3 0.2 0.065 13.8 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4810) Spc7 PF08317.11 EGF81502.1 - 0.0028 16.6 6.1 0.017 14.0 4.2 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF4618 PF15397.6 EGF81502.1 - 0.0034 16.8 5.3 0.0051 16.3 3.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) CREPT PF16566.5 EGF81502.1 - 0.0035 17.5 2.8 0.0045 17.2 2.8 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Prefoldin PF02996.17 EGF81502.1 - 0.0038 17.1 6.3 0.19 11.6 3.1 2.4 2 0 0 2 2 2 1 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 EGF81502.1 - 0.0041 17.4 1.7 0.0049 17.1 1.7 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Dynactin_p22 PF07426.11 EGF81502.1 - 0.0058 16.5 4.1 0.012 15.4 1.9 2.1 2 0 0 2 2 2 1 Dynactin subunit p22 V-SNARE PF05008.15 EGF81502.1 - 0.0059 16.9 4.8 0.0077 16.6 3.8 1.7 1 1 1 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DHR10 PF18595.1 EGF81502.1 - 0.0096 16.0 6.4 1.6 8.8 0.0 2.1 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain BST2 PF16716.5 EGF81502.1 - 0.011 16.3 1.8 0.011 16.3 1.8 1.7 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 Cluap1 PF10234.9 EGF81502.1 - 0.011 15.2 4.3 0.15 11.4 1.7 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 GCN5L1 PF06320.13 EGF81502.1 - 0.011 15.9 2.0 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) ATG16 PF08614.11 EGF81502.1 - 0.016 15.5 4.7 0.088 13.0 2.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EGF81502.1 - 0.016 15.0 5.3 0.018 14.8 3.5 2.0 2 1 0 2 2 2 0 Septum formation initiator DUF5082 PF16888.5 EGF81502.1 - 0.019 15.3 5.6 1.1 9.6 0.0 2.7 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) KxDL PF10241.9 EGF81502.1 - 0.02 15.1 3.3 0.26 11.6 1.7 2.2 1 1 2 3 3 3 0 Uncharacterized conserved protein AIP3 PF03915.13 EGF81502.1 - 0.023 13.8 3.0 0.04 13.0 3.0 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 Atg14 PF10186.9 EGF81502.1 - 0.025 13.7 1.3 0.032 13.3 1.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 EGF81502.1 - 0.026 14.6 2.2 0.35 11.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 EGF81502.1 - 0.026 14.9 5.5 0.31 11.5 3.4 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 EGF81502.1 - 0.026 14.6 8.1 0.92 9.6 4.9 2.1 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Cytochrom_B562 PF07361.11 EGF81502.1 - 0.028 15.1 1.2 0.045 14.4 1.2 1.4 1 0 0 1 1 1 0 Cytochrome b562 DUF1664 PF07889.12 EGF81502.1 - 0.029 14.4 4.5 2.1 8.4 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_lid_9 PF17871.1 EGF81502.1 - 0.029 14.3 3.9 1.4 8.9 2.6 2.1 1 1 1 2 2 2 0 AAA lid domain UPF0242 PF06785.11 EGF81502.1 - 0.029 14.5 4.3 0.037 14.1 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 EGF81502.1 - 0.035 13.8 5.1 4 7.0 0.0 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MSP1_C PF07462.11 EGF81502.1 - 0.04 12.6 3.2 0.033 12.9 2.2 1.4 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CAMP_factor PF07373.11 EGF81502.1 - 0.043 13.4 4.2 0.096 12.3 3.3 1.7 1 1 1 2 2 2 0 CAMP factor (Cfa) Erf4 PF10256.9 EGF81502.1 - 0.045 13.9 0.3 0.39 10.8 0.1 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family BLOC1_2 PF10046.9 EGF81502.1 - 0.058 13.7 4.8 0.48 10.7 2.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 EGF81502.1 - 0.07 11.8 5.6 0.38 9.3 3.9 1.8 1 1 1 2 2 2 0 AAA domain FapA PF03961.13 EGF81502.1 - 0.082 11.5 4.2 0.098 11.3 4.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 EGF81502.1 - 0.098 12.5 7.0 0.14 11.9 6.5 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TBCA PF02970.16 EGF81502.1 - 0.11 12.8 4.4 0.13 12.6 2.4 1.9 1 1 0 2 2 2 0 Tubulin binding cofactor A TMF_DNA_bd PF12329.8 EGF81502.1 - 0.12 12.4 9.1 0.16 12.0 7.8 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 EGF81502.1 - 0.12 12.8 7.0 4.8 7.6 5.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.12 EGF81502.1 - 0.12 12.7 4.9 0.44 10.9 2.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF5446 PF17522.2 EGF81502.1 - 0.13 12.5 4.8 0.32 11.2 2.3 2.5 2 2 0 2 2 2 0 Family of unknown function (DUF5446) TolA_bind_tri PF16331.5 EGF81502.1 - 0.13 12.3 2.4 1.7 8.8 0.6 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Spc24 PF08286.11 EGF81502.1 - 0.15 12.3 3.5 0.27 11.5 1.7 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin_2 PF14523.6 EGF81502.1 - 0.17 12.3 4.3 0.86 10.0 2.2 2.1 1 1 1 2 2 2 0 Syntaxin-like protein DUF16 PF01519.16 EGF81502.1 - 0.18 12.3 4.3 0.26 11.8 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 SseC PF04888.12 EGF81502.1 - 0.24 11.0 4.3 0.14 11.7 2.0 1.6 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family APG6_N PF17675.1 EGF81502.1 - 0.28 11.7 4.7 1.4 9.4 4.7 1.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4795 PF16043.5 EGF81502.1 - 0.28 10.8 6.9 0.49 10.0 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) bZIP_2 PF07716.15 EGF81502.1 - 0.3 11.2 2.3 0.83 9.8 2.3 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Prefoldin_2 PF01920.20 EGF81502.1 - 0.33 10.9 7.7 0.4 10.7 4.2 2.4 2 1 1 3 3 3 0 Prefoldin subunit Uso1_p115_C PF04871.13 EGF81502.1 - 0.37 11.2 7.0 0.32 11.4 5.0 1.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FmiP_Thoc5 PF09766.9 EGF81502.1 - 0.39 9.9 5.9 0.47 9.7 4.2 1.7 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 ABC_tran_CTD PF16326.5 EGF81502.1 - 0.42 10.9 9.8 63 3.9 9.0 3.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Sec2p PF06428.11 EGF81502.1 - 0.51 10.4 7.4 16 5.6 7.1 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 EGF81502.1 - 0.63 10.7 5.9 3.6 8.3 3.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Snapin_Pallidin PF14712.6 EGF81502.1 - 0.66 10.4 7.8 0.48 10.9 5.0 1.9 1 1 1 2 2 2 0 Snapin/Pallidin CC2-LZ PF16516.5 EGF81502.1 - 0.74 10.2 5.8 5.7 7.4 3.8 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SlyX PF04102.12 EGF81502.1 - 0.86 10.3 4.8 3.2 8.4 2.2 2.4 1 1 1 2 2 2 0 SlyX Fib_alpha PF08702.10 EGF81502.1 - 1.7 8.8 7.0 3.2 7.9 3.6 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family LSM PF01423.22 EGF81503.1 - 4e-14 52.1 0.4 5.1e-14 51.7 0.4 1.1 1 0 0 1 1 1 1 LSM domain PTCB-BRCT PF12738.7 EGF81504.1 - 9.3e-49 163.2 1.3 5e-19 68.0 0.0 5.0 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.26 EGF81504.1 - 2.6e-44 149.5 4.7 5.9e-13 49.0 0.0 5.4 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGF81504.1 - 2.7e-21 75.7 0.2 0.00039 20.8 0.0 5.7 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EGF81504.1 - 2.9e-15 55.9 0.1 2.1e-08 33.9 0.0 5.0 5 1 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 EGF81504.1 - 1.7e-08 34.6 0.2 0.93 9.8 0.0 4.9 5 0 0 5 5 5 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGF81504.1 - 1.1e-07 31.8 0.0 2.9 8.0 0.1 5.0 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain SAICAR_synt PF01259.18 EGF81504.1 - 0.068 12.8 0.9 0.12 11.9 0.9 1.4 1 0 0 1 1 1 0 SAICAR synthetase Prominin PF05478.11 EGF81504.1 - 0.087 10.8 1.0 0.15 10.0 1.0 1.3 1 0 0 1 1 1 0 Prominin DUF2797 PF10977.8 EGF81504.1 - 0.12 12.2 3.7 0.32 10.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) PARP PF00644.20 EGF81505.1 - 1.4e-65 220.6 0.1 2.2e-65 219.9 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGF81505.1 - 1.4e-47 161.2 3.3 2.6e-47 160.4 3.3 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGF81505.1 - 3.3e-26 91.1 3.3 5e-26 90.6 2.2 1.9 2 0 0 2 2 2 1 WGR domain RRM_1 PF00076.22 EGF81507.1 - 2.1e-35 120.3 0.0 1.2e-17 63.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGF81507.1 - 0.011 15.8 0.0 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Pro_isomerase PF00160.21 EGF81508.1 - 1.3e-33 116.5 0.1 3.2e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGF81508.1 - 1.1e-14 54.0 0.1 2e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 EGF81509.1 - 9.9e-85 284.4 0.1 1.2e-84 284.1 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF81509.1 - 5.4e-15 55.6 0.0 1.3e-14 54.4 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding Aquarius_N PF16399.5 EGF81510.1 - 1.6e-181 605.3 0.0 1.1e-179 599.3 0.0 2.1 1 1 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EGF81510.1 - 1.2e-19 70.7 0.0 2.3e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGF81510.1 - 7.8e-07 29.1 0.2 1.4e-05 25.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGF81510.1 - 4.3e-05 23.6 0.1 0.003 17.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGF81510.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGF81510.1 - 0.00035 20.4 0.2 0.02 14.7 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGF81510.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF81510.1 - 0.0041 17.5 0.4 0.024 15.0 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EGF81510.1 - 0.012 15.5 0.1 0.084 12.8 0.0 2.5 3 0 0 3 3 3 0 NACHT domain DUF2075 PF09848.9 EGF81510.1 - 0.021 14.1 0.1 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EGF81510.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGF81510.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 EGF81510.1 - 0.18 12.2 0.1 0.79 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Med26 PF08711.11 EGF81511.1 - 1.1e-12 47.7 0.2 3.5e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Adaptin_binding PF10199.9 EGF81511.1 - 0.25 12.0 10.0 18 5.9 9.3 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Leo1 PF04004.13 EGF81512.1 - 2.9e-47 160.6 1.3 2.9e-47 160.6 1.3 1.7 2 0 0 2 2 2 1 Leo1-like protein Diphthamide_syn PF01866.17 EGF81512.1 - 0.042 13.3 0.5 0.068 12.6 0.3 1.4 1 1 0 1 1 1 0 Putative diphthamide synthesis protein WD40 PF00400.32 EGF81513.1 - 2.3e-10 40.9 0.8 0.00058 20.6 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81513.1 - 9.8e-08 32.2 0.0 2.4 8.5 0.0 4.7 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF81513.1 - 0.0089 15.4 0.0 0.44 9.8 0.0 2.9 3 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EGF81513.1 - 0.023 13.7 0.0 0.049 12.6 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF81513.1 - 0.14 10.8 1.7 1.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 NDK PF00334.19 EGF81514.1 - 3.8e-32 111.1 0.0 4.5e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 EGF81514.1 - 2.2e-14 52.9 0.1 3.6e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif RasGEF PF00617.19 EGF81515.1 - 7.8e-48 163.0 2.0 1.4e-47 162.2 0.1 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGF81515.1 - 4.2e-19 68.7 0.9 1.7e-18 66.8 0.9 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif RBD PF02196.15 EGF81515.1 - 5.9e-07 29.5 0.0 0.042 13.9 0.1 2.7 2 0 0 2 2 2 2 Raf-like Ras-binding domain UCH PF00443.29 EGF81516.1 - 5e-33 114.7 0.2 7.8e-33 114.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGF81516.1 - 6.5e-09 36.0 0.1 1.5e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGF81516.1 - 2.2e-06 27.5 0.0 5.6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase OB_NTP_bind PF07717.16 EGF81517.1 - 2.1e-22 79.3 0.0 5.1e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGF81517.1 - 3.3e-17 62.7 0.0 7.3e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGF81517.1 - 5.7e-15 55.6 0.0 1.4e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGF81517.1 - 2.2e-06 27.6 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF81517.1 - 8.5e-05 22.8 0.0 0.00039 20.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGF81517.1 - 0.0015 18.9 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF81517.1 - 0.0015 18.3 0.0 0.0061 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGF81517.1 - 0.006 15.7 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 EGF81517.1 - 0.012 15.7 0.7 2 8.4 0.7 2.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EGF81517.1 - 0.078 12.6 0.3 2 8.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGF81517.1 - 0.096 12.0 0.1 0.24 10.7 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EGF81517.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGF81517.1 - 0.18 12.3 0.1 0.76 10.3 0.0 1.8 1 1 0 2 2 2 0 ABC transporter Polysacc_deac_1 PF01522.21 EGF81519.1 - 3.8e-09 36.5 0.0 7.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase LON_substr_bdg PF02190.16 EGF81520.1 - 1.8e-12 47.6 0.0 1.4e-11 44.7 0.0 2.3 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EGF81520.1 - 2.7e-10 39.9 25.0 4.9e-06 26.3 16.5 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF81520.1 - 4e-09 36.2 19.6 2.2e-06 27.4 11.1 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF81520.1 - 1.3e-08 34.7 21.5 0.00032 20.6 1.1 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EGF81520.1 - 1.7e-08 34.2 23.3 3.1e-05 23.8 15.2 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF81520.1 - 1e-07 32.2 24.0 1e-05 25.8 15.6 2.9 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 EGF81520.1 - 1.8e-07 31.2 23.8 3.2e-05 24.0 2.0 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGF81520.1 - 1.7e-05 24.7 19.7 0.0036 17.2 12.2 2.9 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 EGF81520.1 - 0.00011 21.9 20.5 0.011 15.5 13.3 2.9 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGF81520.1 - 0.0037 17.3 15.0 0.091 12.9 1.2 3.0 2 0 0 2 2 2 2 zinc RING finger of MSL2 DUF3856 PF12968.7 EGF81520.1 - 0.097 12.7 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) zf-rbx1 PF12678.7 EGF81520.1 - 0.12 12.6 10.9 0.56 10.5 10.9 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGF81520.1 - 0.28 11.0 20.2 3.3 7.6 11.5 3.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 EGF81521.1 - 1.2e-16 60.8 28.2 5.2e-05 23.9 0.0 9.6 9 0 0 9 9 9 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGF81521.1 - 0.55 9.1 7.4 10 4.9 0.1 4.8 5 2 1 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF81521.1 - 0.65 8.6 10.8 1 7.9 0.1 4.7 4 2 1 6 6 6 0 Nucleoporin Nup120/160 Ribonuc_red_sm PF00268.21 EGF81522.1 - 9.3e-116 386.1 0.2 1.1e-115 385.9 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Haem_oxygenas_2 PF14518.6 EGF81522.1 - 0.09 12.5 0.1 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Iron-containing redox enzyme Lipase_3 PF01764.25 EGF81523.1 - 1.7e-19 70.1 0.0 3.4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF775 PF05603.12 EGF81524.1 - 2.4e-47 161.0 0.0 8.8e-47 159.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Tom22 PF04281.13 EGF81525.1 - 2.1e-28 98.9 6.3 9.8e-27 93.4 0.3 2.0 1 1 1 2 2 2 2 Mitochondrial import receptor subunit Tom22 Claudin_2 PF13903.6 EGF81525.1 - 0.098 12.4 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DNA_pol_phi PF04931.13 EGF81525.1 - 6.5 4.7 12.2 8.6 4.3 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi GST_C_3 PF14497.6 EGF81526.1 - 4.2e-15 55.7 0.0 8.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGF81526.1 - 3.8e-10 40.0 0.0 4.4e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGF81526.1 - 5.2e-07 30.0 0.0 2.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF81526.1 - 2e-06 28.0 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGF81526.1 - 0.00035 20.5 0.3 0.0008 19.4 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGF81526.1 - 0.00051 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGF81526.1 - 0.0075 17.0 0.0 0.028 15.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGF81526.1 - 0.064 13.6 0.0 0.21 11.9 0.0 1.7 1 1 1 2 2 2 0 Outer mitochondrial membrane transport complex protein ABC_membrane PF00664.23 EGF81527.1 - 1.1e-40 140.0 11.7 1.6e-40 139.5 11.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGF81527.1 - 9.3e-33 113.6 0.0 2e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGF81527.1 - 1.4e-06 28.0 0.0 0.00018 21.0 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF81527.1 - 0.0034 17.8 0.0 0.0079 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGF81527.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGF81527.1 - 0.02 15.2 0.0 0.052 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGF81527.1 - 0.02 14.7 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EGF81527.1 - 0.028 14.4 0.2 0.22 11.4 0.0 2.5 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_29 PF13555.6 EGF81527.1 - 0.03 14.1 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EGF81527.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EGF81527.1 - 0.055 12.6 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 EGF81527.1 - 0.072 13.5 0.1 0.41 11.1 0.0 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGF81527.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EGF81527.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1659 PF07872.11 EGF81527.1 - 0.22 11.2 0.7 5.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) LSM PF01423.22 EGF81528.1 - 3.1e-18 65.2 0.5 3.4e-18 65.1 0.5 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF81528.1 - 0.0071 16.5 0.1 0.0088 16.2 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGF81528.1 - 0.12 12.5 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Glycos_transf_1 PF00534.20 EGF81530.1 - 3.1e-23 82.2 0.0 1.3e-13 50.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF81530.1 - 3.1e-22 79.5 0.0 1.1e-12 48.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGF81530.1 - 6.6e-07 29.5 0.2 1.1e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGF81530.1 - 0.012 16.0 0.0 0.039 14.4 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGF81530.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Endosulfine PF04667.17 EGF81531.1 - 1.3e-25 89.3 1.6 1.9e-25 88.8 1.6 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region adh_short_C2 PF13561.6 EGF81532.1 - 2.7e-57 194.0 0.6 3.9e-57 193.5 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGF81532.1 - 5.3e-40 137.0 0.8 1.1e-39 135.9 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGF81532.1 - 0.0026 17.7 0.2 0.0046 16.9 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF81532.1 - 0.004 16.7 0.1 0.0052 16.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGF81532.1 - 0.058 13.3 0.2 0.1 12.4 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fib_alpha PF08702.10 EGF81533.1 - 0.76 10.0 9.8 0.5 10.5 4.9 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MCM6_C PF18263.1 EGF81533.1 - 2.1 8.6 5.8 6.9 7.0 4.0 2.3 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Med9 PF07544.13 EGF81533.1 - 7.6 6.7 13.2 28 4.9 0.1 3.4 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Cauli_AT PF03233.13 EGF81534.1 - 0.00073 19.5 1.2 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 Aphid transmission protein TMF_DNA_bd PF12329.8 EGF81534.1 - 0.0057 16.6 2.1 0.014 15.4 2.1 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding AIP3 PF03915.13 EGF81534.1 - 0.018 14.2 3.1 0.024 13.7 3.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF16 PF01519.16 EGF81534.1 - 0.037 14.5 1.5 0.054 14.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 RasGAP_C PF03836.15 EGF81534.1 - 0.1 12.8 1.9 0.19 11.9 1.9 1.4 1 0 0 1 1 1 0 RasGAP C-terminus GIT_CC PF16559.5 EGF81534.1 - 0.17 11.8 1.2 0.43 10.5 1.2 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Dad4 PF08650.10 EGF81534.1 - 0.37 10.8 2.7 3.5 7.7 0.8 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad4 Tom37_C PF11801.8 EGF81535.1 - 0.071 13.1 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain Ras PF00071.22 EGF81536.1 - 7.6e-56 188.2 0.0 9.1e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF81536.1 - 2.2e-22 79.5 0.0 3.4e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF81536.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGF81536.1 - 0.0023 17.4 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGF81536.1 - 0.074 12.4 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Lipase_GDSL_2 PF13472.6 EGF81537.1 - 3.2e-08 34.2 0.0 3e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGF81537.1 - 3.1e-05 24.1 0.0 0.0046 16.9 0.0 2.2 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase TB2_DP1_HVA22 PF03134.19 EGF81538.1 - 3.3e-06 26.9 3.1 3.3e-06 26.9 3.1 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF3419 PF11899.8 EGF81539.1 - 1.1e-116 390.3 0.0 1.2e-116 390.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DUF2627 PF11118.8 EGF81540.1 - 7.3 7.2 7.2 8.8 7.0 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Ribosomal_L37e PF01907.19 EGF81541.1 - 3.8e-27 94.2 12.2 6.2e-27 93.5 12.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EGF81541.1 - 0.042 13.9 2.3 0.061 13.4 2.3 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_10 PF16685.5 EGF81541.1 - 0.12 12.5 2.9 0.16 12.2 2.9 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Velvet PF11754.8 EGF81542.1 - 1.6e-24 87.3 0.0 1.9e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Pro_isomerase PF00160.21 EGF81543.1 - 1e-44 152.6 0.1 2.5e-44 151.3 0.1 1.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ARPC4 PF05856.12 EGF81544.1 - 3.1e-80 267.7 5.0 3.4e-80 267.5 5.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Rotamase PF00639.21 EGF81545.1 - 5.3e-23 81.8 0.0 7.5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGF81545.1 - 1.2e-19 71.0 0.1 1.6e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EGF81545.1 - 3.6e-05 23.7 3.5 5.3e-05 23.2 1.9 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EGF81545.1 - 8.4e-05 23.4 0.0 0.00013 22.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 EGF81545.1 - 0.1 13.3 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 X8 domain FKBP_C PF00254.28 EGF81546.1 - 4.9e-26 90.9 0.0 8.9e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGF81546.1 - 5.1e-12 44.9 0.9 0.0088 16.1 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGF81546.1 - 2.5e-11 42.9 5.1 3.1e-05 23.6 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81546.1 - 9.3e-08 31.7 1.8 0.012 15.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81546.1 - 3.6e-07 30.4 1.3 0.00079 19.7 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81546.1 - 5.1e-06 26.9 0.3 0.0011 19.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF81546.1 - 3.4e-05 23.6 0.4 0.074 13.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81546.1 - 0.00012 22.6 0.0 0.054 14.3 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGF81546.1 - 0.0004 20.1 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF81546.1 - 0.0024 18.5 0.2 4.5 8.0 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF81546.1 - 0.0077 16.8 0.8 3.8 8.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGF81546.1 - 0.0083 15.9 1.8 0.24 11.1 1.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 EGF81546.1 - 0.011 15.9 3.6 0.015 15.5 0.4 2.2 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGF81546.1 - 0.014 15.1 0.9 14 5.4 0.0 3.2 2 1 2 4 4 4 0 TPR repeat TPR_17 PF13431.6 EGF81546.1 - 0.075 13.4 0.2 9 6.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MgsA_C PF12002.8 EGF81548.1 - 2.5e-56 190.2 0.1 4.4e-56 189.4 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGF81548.1 - 2.7e-23 82.1 0.1 4.9e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGF81548.1 - 5.9e-17 62.3 0.0 1.6e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGF81548.1 - 1.3e-15 57.5 0.0 2.9e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGF81548.1 - 3.1e-07 30.5 0.0 1.4e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGF81548.1 - 6.9e-07 28.9 0.1 0.019 14.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGF81548.1 - 4.4e-06 27.2 0.1 0.00058 20.3 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EGF81548.1 - 4.5e-06 26.1 0.0 7.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 EGF81548.1 - 9.2e-06 25.7 0.1 2.8e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EGF81548.1 - 1.5e-05 25.1 0.0 3.5e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF81548.1 - 6.1e-05 23.6 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGF81548.1 - 6.4e-05 23.2 0.1 0.003 17.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGF81548.1 - 8.8e-05 22.3 0.0 0.051 13.3 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGF81548.1 - 0.00055 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGF81548.1 - 0.00068 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EGF81548.1 - 0.00081 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase zf-WRNIP1_ubi PF18279.1 EGF81548.1 - 0.00087 19.8 0.3 0.0038 17.8 0.3 2.2 1 0 0 1 1 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain AAA_19 PF13245.6 EGF81548.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGF81548.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGF81548.1 - 0.0013 18.5 0.0 0.016 15.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 EGF81548.1 - 0.002 18.5 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF81548.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGF81548.1 - 0.0037 16.5 0.0 0.01 15.1 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain Sigma54_activ_2 PF14532.6 EGF81548.1 - 0.0046 17.1 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 EGF81548.1 - 0.0049 17.2 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EGF81548.1 - 0.005 16.8 0.0 0.022 14.7 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EGF81548.1 - 0.005 16.6 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase ABC_tran PF00005.27 EGF81548.1 - 0.0074 16.8 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter ResIII PF04851.15 EGF81548.1 - 0.0084 16.1 0.1 2.5 8.0 0.1 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_2 PF07724.14 EGF81548.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 EGF81548.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGF81548.1 - 0.016 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EGF81548.1 - 0.018 14.5 0.0 0.12 11.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial TniB protein AAA_3 PF07726.11 EGF81548.1 - 0.024 14.5 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGF81548.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EGF81548.1 - 0.034 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf_UBZ PF18439.1 EGF81548.1 - 0.047 13.3 0.1 0.098 12.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Zeta_toxin PF06414.12 EGF81548.1 - 0.051 12.9 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 EGF81548.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_ligase_A_N PF04675.14 EGF81548.1 - 0.066 13.5 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 1 0 DNA ligase N terminus KTI12 PF08433.10 EGF81548.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 zf-C2HC_2 PF13913.6 EGF81548.1 - 0.1 12.5 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 1 0 zinc-finger of a C2HC-type Cytidylate_kin2 PF13189.6 EGF81548.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family dNK PF01712.19 EGF81548.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_7 PF12775.7 EGF81548.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EGF81548.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNF220 PF15926.5 EGF81548.1 - 0.17 11.5 0.7 0.29 10.7 0.7 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 PhoH PF02562.16 EGF81548.1 - 0.18 11.2 0.0 0.46 9.9 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein NTPase_1 PF03266.15 EGF81548.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase ASH PF15780.5 EGF81550.1 - 1.6e-15 57.1 3.0 0.0022 18.2 0.1 7.2 6 0 0 6 6 6 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EGF81550.1 - 0.0045 17.0 0.4 4.4 7.4 0.0 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1573) UDG PF03167.19 EGF81551.1 - 1.2e-24 87.1 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sec5 PF15469.6 EGF81552.1 - 0.0011 18.8 1.9 0.0011 18.8 1.9 2.9 3 1 0 3 3 3 1 Exocyst complex component Sec5 Lant_dehydr_C PF14028.6 EGF81552.1 - 0.0026 17.4 1.9 0.0039 16.8 1.9 1.3 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term Cep57_CLD_2 PF14197.6 EGF81552.1 - 0.0026 17.8 1.8 0.0026 17.8 1.8 4.3 3 1 1 4 4 4 1 Centrosome localisation domain of PPC89 Synaptobrevin PF00957.21 EGF81552.1 - 0.25 11.2 7.6 0.61 9.9 2.4 2.7 1 1 1 2 2 2 0 Synaptobrevin DUF3209 PF11483.8 EGF81552.1 - 1.4 9.4 15.0 0.18 12.3 6.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) PKcGMP_CC PF16808.5 EGF81552.1 - 2.7 7.9 24.5 0.33 10.8 5.7 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fez1 PF06818.15 EGF81552.1 - 4.5 7.7 24.4 3 8.3 10.2 2.3 1 1 1 2 2 2 0 Fez1 TraF PF13728.6 EGF81552.1 - 5 6.9 7.3 0.94 9.2 2.6 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein Pga1 PF10333.9 EGF81552.1 - 7.6 6.4 8.8 20 5.0 4.6 2.9 2 1 0 2 2 2 0 GPI-Mannosyltransferase II co-activator FOXP-CC PF16159.5 EGF81552.1 - 8.7 7.1 9.0 2.3 8.9 4.7 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF4246 PF14033.6 EGF81554.1 - 1.3e-79 268.5 0.3 1.4e-79 268.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF4246 PF14033.6 EGF81555.1 - 0.00064 18.9 0.1 0.00073 18.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Glyoxalase_2 PF12681.7 EGF81556.1 - 6.2e-06 26.1 0.0 7.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EGF81556.1 - 0.0011 19.2 0.1 0.0011 19.2 0.1 1.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gti1_Pac2 PF09729.9 EGF81559.1 - 2.9e-43 148.1 0.0 8.9e-43 146.5 0.0 1.9 1 1 0 1 1 1 1 Gti1/Pac2 family Cuticle_4 PF15955.5 EGF81559.1 - 7.4 7.3 9.9 0.95 10.2 3.4 2.7 3 0 0 3 3 3 0 Cuticle protein Syntaxin PF00804.25 EGF81560.1 - 2.1e-29 102.6 16.2 3.1e-29 102.1 16.2 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EGF81560.1 - 1.4e-14 53.8 1.4 4.9e-14 52.1 0.1 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EGF81560.1 - 1.2e-07 32.0 9.1 1.2e-07 32.0 9.1 2.8 2 1 1 3 3 3 1 Syntaxin-like protein Hum_adeno_E3A PF05393.11 EGF81560.1 - 0.12 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein CENP-H PF05837.12 EGF81560.1 - 0.28 11.6 14.2 0.17 12.3 1.0 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) HAUS-augmin3 PF14932.6 EGF81560.1 - 0.36 10.4 10.8 0.3 10.6 2.1 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 VSG_B PF13206.6 EGF81560.1 - 0.67 9.2 9.8 28 3.8 9.8 2.1 1 1 0 1 1 1 0 Trypanosomal VSG domain Baculo_PEP_C PF04513.12 EGF81560.1 - 1.8 8.6 8.6 0.99 9.4 1.2 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.11 EGF81560.1 - 2.3 7.7 9.0 1.5 8.2 1.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_13 PF13166.6 EGF81560.1 - 6.5 5.3 12.6 0.16 10.6 1.1 2.1 1 1 1 2 2 2 0 AAA domain SKA2 PF16740.5 EGF81560.1 - 7.4 6.4 15.2 0.076 12.8 2.6 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Lung_7-TM_R PF06814.13 EGF81561.1 - 9.2e-59 199.1 24.4 1.2e-58 198.8 24.4 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor V_ATPase_I PF01496.19 EGF81561.1 - 0.0059 14.6 0.1 0.0059 14.6 0.1 1.5 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family zf-C2H2_jaz PF12171.8 EGF81562.1 - 1e-08 35.2 1.5 1.6e-08 34.6 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 EGF81562.1 - 0.032 14.9 0.0 0.051 14.2 0.0 1.3 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 EGF81562.1 - 0.073 13.4 1.0 0.086 13.2 0.4 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CRAL_TRIO PF00650.20 EGF81563.1 - 2.4e-33 115.1 0.0 3.4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGF81563.1 - 3.2e-06 27.2 1.7 7.9e-06 26.0 1.7 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGF81563.1 - 0.0011 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cu-oxidase_3 PF07732.15 EGF81564.1 - 4.5e-35 120.2 3.1 3.5e-31 107.7 1.4 3.7 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGF81564.1 - 1.7e-33 115.3 1.9 1.7e-33 115.3 1.9 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EGF81564.1 - 8.4e-33 113.7 0.4 4.6e-29 101.6 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase zf-H2C2_2 PF13465.6 EGF81565.1 - 5.4e-08 32.9 9.6 1.3e-06 28.6 6.0 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGF81565.1 - 4.7e-06 26.8 15.2 0.0015 18.9 4.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF81565.1 - 0.0054 17.5 11.6 0.031 15.1 3.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.18 EGF81565.1 - 0.0065 17.1 1.6 0.0087 16.7 1.6 1.2 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_6 PF13912.6 EGF81565.1 - 0.085 12.9 1.5 0.085 12.9 1.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EGF81565.1 - 0.12 12.8 3.5 0.51 10.8 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Myticin-prepro PF10690.9 EGF81566.1 - 0.091 13.0 0.1 0.25 11.6 0.0 1.7 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Plasmodium_Vir PF05795.11 EGF81566.1 - 0.62 9.4 2.5 0.77 9.1 2.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FTR1 PF03239.14 EGF81567.1 - 7.3e-56 189.6 11.3 9e-56 189.3 11.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family CoA_binding_3 PF13727.6 EGF81567.1 - 0.03 14.3 0.6 0.03 14.3 0.6 2.3 2 0 0 2 2 2 0 CoA-binding domain DUF2516 PF10724.9 EGF81567.1 - 0.034 14.4 7.8 0.25 11.7 7.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) ESSS PF10183.9 EGF81567.1 - 0.34 11.1 2.9 0.84 9.9 0.4 2.7 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phage_holin_3_6 PF07332.11 EGF81567.1 - 0.51 10.4 19.0 0.19 11.7 6.4 3.0 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III STT3 PF02516.14 EGF81568.1 - 1.5e-135 452.9 43.4 1.4e-132 443.1 37.1 2.1 1 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit HMMR_C PF15908.5 EGF81569.1 - 3.3e-07 30.7 9.6 3.3e-07 30.7 9.6 1.7 1 1 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal Pox_A_type_inc PF04508.12 EGF81569.1 - 0.024 14.5 1.7 0.09 12.7 1.7 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 EGF81569.1 - 0.037 14.0 26.8 0.033 14.2 13.2 2.8 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZIP4_domain PF18292.1 EGF81569.1 - 0.091 12.7 1.5 0.17 11.8 1.5 1.5 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain Nudix_hydro PF18290.1 EGF81569.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Nudix hydrolase domain RcbX PF02341.15 EGF81569.1 - 0.13 12.5 4.4 0.068 13.4 1.9 1.8 2 1 0 2 2 2 0 RbcX protein Goodbye PF17109.5 EGF81569.1 - 1.2 9.6 3.8 3.7 8.0 0.1 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Fib_alpha PF08702.10 EGF81569.1 - 6.1 7.0 11.1 9.8 6.4 7.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OPT PF03169.15 EGF81571.1 - 6.9e-129 431.2 55.0 8e-129 431.1 55.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Oleosin PF01277.17 EGF81571.1 - 0.25 11.1 2.9 0.6 9.9 0.0 3.0 2 0 0 2 2 2 0 Oleosin AHD PF17793.1 EGF81574.1 - 0.16 11.8 1.0 0.5 10.2 0.3 2.1 2 1 0 2 2 2 0 ANC1 homology domain (AHD) RPN2_C PF18004.1 EGF81575.1 - 1.3e-43 148.6 3.0 2.1e-43 148.0 3.0 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGF81575.1 - 6.1e-42 140.0 16.1 2.8e-07 30.6 0.0 8.9 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGF81575.1 - 3.7e-20 72.1 1.9 1e-11 45.0 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EGF81575.1 - 6.8e-07 29.7 1.6 0.055 14.0 0.0 4.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EGF81575.1 - 0.00012 22.0 0.2 5.5 7.5 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 EGF81575.1 - 0.0048 17.4 2.0 15 6.6 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RIB43A PF05914.12 EGF81576.1 - 2.2e-102 342.6 59.3 2.5e-102 342.5 59.3 1.0 1 0 0 1 1 1 1 RIB43A NCE101 PF11654.8 EGF81577.1 - 0.079 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Non-classical export protein 1 FKBP_C PF00254.28 EGF81578.1 - 4.3e-32 110.3 0.0 1.2e-31 108.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EGF81578.1 - 1.3e-18 67.5 0.0 1.3e-18 67.5 0.0 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 EGF81578.1 - 0.00012 22.2 17.4 0.00018 21.7 17.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 EGF81578.1 - 0.3 9.3 22.1 0.39 8.9 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGF81578.1 - 0.36 9.1 16.2 0.47 8.7 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 EGF81578.1 - 0.68 7.0 7.7 0.8 6.8 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 EGF81578.1 - 1.1 8.0 6.8 1.7 7.3 6.8 1.4 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 EGF81578.1 - 3.7 6.0 26.8 4.8 5.7 26.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-RING_2 PF13639.6 EGF81579.1 - 2e-12 47.2 5.5 3e-12 46.6 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF81579.1 - 2e-08 33.9 5.2 3.6e-08 33.1 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF81579.1 - 6.3e-08 32.8 11.0 7.7e-08 32.5 9.6 1.9 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGF81579.1 - 1.3e-07 31.2 4.6 2.6e-07 30.3 4.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF81579.1 - 3.9e-06 26.6 4.6 6.7e-06 25.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF81579.1 - 0.00014 21.8 3.7 0.00022 21.1 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF81579.1 - 0.00021 21.2 5.3 0.00044 20.2 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGF81579.1 - 0.00038 20.4 4.0 0.0012 18.9 4.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGF81579.1 - 0.0055 16.5 3.6 0.0097 15.7 3.6 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Endonuclease_7 PF02945.15 EGF81579.1 - 0.0099 15.8 1.6 0.011 15.6 1.2 1.4 1 1 0 1 1 1 1 Recombination endonuclease VII zf-RING-like PF08746.11 EGF81579.1 - 0.26 11.6 4.5 0.44 10.9 4.5 1.4 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 EGF81579.1 - 0.38 10.4 7.6 0.94 9.1 7.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGF81579.1 - 0.42 10.8 7.6 3.2 8.0 7.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EGF81579.1 - 0.59 10.1 4.9 1.4 8.9 4.9 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EGF81579.1 - 0.64 9.9 5.1 1.2 9.0 5.1 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EGF81579.1 - 1.2 9.4 5.8 3.9 7.7 5.8 1.9 1 1 0 1 1 1 0 RING-variant domain zinc_ribbon_16 PF17034.5 EGF81579.1 - 1.6 9.0 6.4 0.6 10.3 3.4 1.7 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 EGF81579.1 - 4.4 7.4 7.4 12 6.1 7.4 1.8 1 1 0 1 1 1 0 Zinc-finger Exonuc_VII_L PF02601.15 EGF81580.1 - 1.3 8.5 21.8 2.3 7.7 4.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Mis12 PF05859.12 EGF81580.1 - 9.8 6.2 14.0 4.8 7.2 0.9 3.1 4 0 0 4 4 4 0 Mis12 protein DUF2951 PF11166.8 EGF81581.1 - 0.014 15.6 1.8 0.02 15.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Mitoc_L55 PF09776.9 EGF81581.1 - 0.063 13.0 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 DUF4246 PF14033.6 EGF81582.1 - 2.1e-84 284.3 0.2 2.5e-84 284.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) F-box-like PF12937.7 EGF81583.1 - 0.016 15.1 0.2 0.043 13.7 0.2 1.7 1 0 0 1 1 1 0 F-box-like PH_17 PF18012.1 EGF81583.1 - 0.61 9.9 3.7 0.79 9.5 0.9 2.4 3 0 0 3 3 3 0 PH domain MCD PF05292.11 EGF81584.1 - 7.2e-95 317.4 0.0 1.1e-94 316.9 0.0 1.3 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 EGF81584.1 - 1.1e-15 57.6 0.1 2.2e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain Methyltransf_16 PF10294.9 EGF81585.1 - 4e-24 85.3 0.1 8.5e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGF81585.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF81585.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NDUFA12 PF05071.16 EGF81587.1 - 1.7e-31 108.9 2.3 2.2e-31 108.6 2.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Halo_GVPC PF05465.13 EGF81587.1 - 0.13 12.6 0.2 0.73 10.1 0.0 2.0 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat SNF2_N PF00176.23 EGF81588.1 - 1.2e-68 231.4 0.0 1.2e-68 231.4 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF81588.1 - 8e-19 68.0 0.0 7.6e-18 64.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 EGF81588.1 - 5.9e-18 65.0 4.0 5.9e-18 65.0 4.0 3.1 3 0 0 3 3 3 1 HSA SnAC PF14619.6 EGF81588.1 - 1.6e-16 60.7 0.7 1.6e-16 60.7 0.7 3.3 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 EGF81588.1 - 1.4e-13 50.7 0.2 4.2e-13 49.2 0.2 1.8 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 EGF81588.1 - 1.5e-10 40.6 0.3 4.2e-10 39.2 0.3 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 EGF81588.1 - 4.3e-09 36.6 0.1 2.9e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vps5 PF09325.10 EGF81589.1 - 8e-17 61.6 2.1 1.5e-14 54.1 0.9 2.2 2 0 0 2 2 2 2 Vps5 C terminal like PX PF00787.24 EGF81589.1 - 9.8e-09 35.2 0.7 7.5e-07 29.1 0.0 2.6 2 1 0 2 2 2 1 PX domain YscO PF07321.12 EGF81589.1 - 0.022 14.7 0.8 4.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO DUF2009 PF09418.10 EGF81589.1 - 0.06 12.4 2.8 0.083 11.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) RNase_T PF00929.24 EGF81590.1 - 0.00083 19.9 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF5419 PF17441.2 EGF81590.1 - 0.0062 16.6 0.0 0.029 14.5 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5419) DNA_pol_A_exo1 PF01612.20 EGF81590.1 - 0.057 13.1 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease Lustrin_cystein PF14625.6 EGF81591.1 - 0.021 15.2 0.8 0.051 13.9 0.8 1.7 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain DCP1 PF06058.13 EGF81593.1 - 6.1e-41 139.0 0.0 6.8e-41 138.9 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family GTP_EFTU PF00009.27 EGF81594.1 - 1.9e-53 180.9 0.0 3.2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGF81594.1 - 1e-39 135.3 0.0 2.1e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGF81594.1 - 1.5e-15 57.3 0.9 1.5e-15 57.3 0.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF81594.1 - 0.001 19.1 0.1 0.031 14.4 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGF81594.1 - 0.043 13.7 2.8 0.05 13.5 0.6 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 EGF81594.1 - 0.13 12.3 0.3 0.49 10.5 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Ribosomal_L13e PF01294.18 EGF81595.1 - 1e-76 256.8 0.8 1.2e-76 256.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e adh_short PF00106.25 EGF81597.1 - 2.3e-40 138.1 0.0 3.2e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF81597.1 - 2.9e-31 108.8 0.0 3.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF81597.1 - 1e-05 25.5 0.5 3.5e-05 23.8 0.5 1.7 1 1 0 1 1 1 1 KR domain TMEM223 PF14640.6 EGF81598.1 - 1.6e-08 34.9 0.0 6.3e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Transmembrane protein 223 MbeD_MobD PF04899.12 EGF81599.1 - 2.2e-06 27.7 2.1 6.9e-06 26.1 2.1 1.9 1 0 0 1 1 1 1 MbeD/MobD like GAS PF13851.6 EGF81599.1 - 0.0011 18.3 2.0 0.0019 17.6 2.0 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 EGF81599.1 - 0.023 14.7 1.5 0.23 11.5 1.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.12 EGF81599.1 - 0.027 13.0 3.7 0.042 12.4 3.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 EGF81599.1 - 0.046 14.3 2.0 0.084 13.4 2.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TRAF_BIRC3_bd PF16673.5 EGF81599.1 - 0.054 13.3 0.1 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain ADIP PF11559.8 EGF81599.1 - 0.18 11.9 3.8 0.44 10.6 3.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.9 EGF81599.1 - 0.2 11.6 2.1 0.31 11.0 2.1 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain PROCN PF08083.11 EGF81600.1 - 7.7e-230 762.6 6.2 1.5e-229 761.6 6.2 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGF81600.1 - 6.4e-126 418.6 0.4 1.1e-125 417.8 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGF81600.1 - 2.2e-87 290.9 2.3 6.5e-87 289.4 2.3 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGF81600.1 - 4.7e-87 289.6 3.6 1.1e-86 288.4 3.6 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGF81600.1 - 8.7e-72 239.5 0.0 1.7e-71 238.5 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EGF81600.1 - 4.2e-50 168.8 0.1 1.5e-49 167.0 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 EGF81600.1 - 4.6e-47 158.3 0.3 1.5e-46 156.7 0.3 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 EGF81600.1 - 2.4e-09 37.2 0.0 1.3e-07 31.7 0.0 2.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3450 PF11932.8 EGF81602.1 - 0.0035 16.7 0.2 0.0075 15.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) MF_alpha_N PF05436.11 EGF81602.1 - 0.022 14.7 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Tup_N PF08581.10 EGF81602.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 Tup N-terminal DUF4246 PF14033.6 EGF81603.1 - 1.1e-97 328.1 0.0 1.4e-97 327.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arm PF00514.23 EGF81603.1 - 0.0027 17.7 0.0 0.015 15.3 0.0 2.4 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat 2OG-FeII_Oxy_5 PF13759.6 EGF81603.1 - 0.1 13.0 0.0 0.92 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase TMPIT PF07851.13 EGF81604.1 - 0.24 10.6 1.8 0.33 10.2 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein WDCP PF15390.6 EGF81604.1 - 1.3 7.3 8.0 1.9 6.8 8.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Peptidase_S41 PF03572.18 EGF81605.1 - 1.1e-10 41.3 0.0 2.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 DUF5314 PF17241.2 EGF81606.1 - 0.058 13.1 0.7 0.065 12.9 0.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5314) eRF1_1 PF03463.15 EGF81607.1 - 1.9e-49 166.9 0.2 3.2e-49 166.2 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EGF81607.1 - 1.4e-30 106.4 0.2 2.7e-30 105.4 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGF81607.1 - 1.4e-20 73.9 0.1 5.3e-20 72.0 0.0 2.0 2 1 0 2 2 2 1 eRF1 domain 3 Peptidase_S9_N PF02897.15 EGF81609.1 - 3.7e-69 233.5 8.5 4.6e-69 233.2 8.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGF81609.1 - 3e-52 177.2 0.0 4.4e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGF81609.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EGF81609.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGF81609.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Forkhead PF00250.18 EGF81610.1 - 4.8e-29 100.4 0.1 8.9e-29 99.6 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain CactinC_cactus PF09732.9 EGF81611.1 - 6.1e-61 203.9 9.5 1.1e-60 203.1 9.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EGF81611.1 - 3.6e-29 101.9 0.1 3.6e-29 101.9 0.1 2.5 3 0 0 3 3 3 1 Conserved mid region of cactin SF3A2 PF16835.5 EGF81611.1 - 0.015 15.6 0.0 0.06 13.7 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) FIST PF08495.10 EGF81612.1 - 1.3e-10 41.5 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 FIST N domain PPR_2 PF13041.6 EGF81614.1 - 3.7e-05 23.8 0.0 0.46 10.7 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_long PF17177.4 EGF81614.1 - 0.00027 20.4 1.1 0.0019 17.6 0.3 2.6 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGF81614.1 - 0.018 15.3 0.0 1.8 9.0 0.0 3.0 2 0 0 2 2 2 0 PPR repeat PPR_3 PF13812.6 EGF81614.1 - 0.042 13.9 0.1 4.1 7.5 0.0 3.3 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DUF4369 PF14289.6 EGF81616.1 - 0.035 14.6 0.1 0.059 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) GSHPx PF00255.19 EGF81618.1 - 3.5e-42 142.4 0.1 4.4e-42 142.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 EGF81618.1 - 1.9e-05 24.4 0.0 0.0094 15.7 0.0 2.1 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EGF81618.1 - 9.5e-05 22.3 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Acetyltransf_1 PF00583.25 EGF81619.1 - 1.6e-09 38.0 0.0 6.1e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF81619.1 - 6.1e-06 26.6 0.0 1.3e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF81619.1 - 0.0061 16.5 0.0 1.8 8.6 0.0 2.8 2 1 1 3 3 3 1 FR47-like protein Acetyltransf_10 PF13673.7 EGF81619.1 - 0.042 13.8 0.0 0.19 11.7 0.0 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGF81619.1 - 0.16 12.1 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AstA PF04958.12 EGF81619.1 - 0.2 10.2 0.0 13 4.2 0.0 2.0 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit Corona_S2 PF01601.16 EGF81620.1 - 0.00087 17.9 2.5 0.00095 17.8 2.5 1.0 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Na_Ala_symp PF01235.17 EGF81620.1 - 1.3 8.2 6.5 1.5 8.0 6.5 1.0 1 0 0 1 1 1 0 Sodium:alanine symporter family MAGE PF01454.19 EGF81621.1 - 2.4e-42 145.0 0.2 3.3e-42 144.6 0.2 1.2 1 0 0 1 1 1 1 MAGE family SBD_N PF07005.11 EGF81621.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-binding N-terminal domain LMBR1 PF04791.16 EGF81622.1 - 7.2e-89 299.0 13.9 3.8e-62 210.9 0.6 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF1772 PF08592.11 EGF81622.1 - 0.008 16.5 3.8 0.0096 16.2 1.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Abhydrolase_6 PF12697.7 EGF81624.1 - 1.5e-10 42.0 0.8 2.6e-10 41.3 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF81624.1 - 8.8e-09 35.0 0.1 3.8e-05 23.1 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGF81624.1 - 3.6e-07 30.1 0.1 2.5e-06 27.3 0.2 2.1 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGF81624.1 - 0.0015 18.4 0.2 0.0024 17.7 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGF81624.1 - 0.003 17.1 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 EGF81624.1 - 0.012 15.4 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydro_lipase PF04083.16 EGF81624.1 - 0.066 12.8 0.0 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_2 PF02230.16 EGF81624.1 - 0.089 12.6 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGF81624.1 - 0.15 11.7 0.0 0.54 9.9 0.0 1.7 1 1 1 2 2 2 0 Serine hydrolase (FSH1) AA_permease_N PF08403.10 EGF81626.1 - 0.17 11.4 0.1 4.2 6.9 0.0 2.1 1 1 1 2 2 2 0 Amino acid permease N-terminal SF3A2 PF16835.5 EGF81627.1 - 6.4e-39 132.2 0.0 9.6e-39 131.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGF81627.1 - 4e-07 30.2 1.7 4e-07 30.2 1.7 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGF81627.1 - 0.0059 16.5 0.1 0.0099 15.8 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Pkinase PF00069.25 EGF81628.1 - 9.6e-68 228.4 0.0 1.1e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81628.1 - 3.3e-37 128.2 0.0 4.1e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81628.1 - 6.8e-07 28.9 0.3 0.002 17.5 0.1 2.6 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGF81628.1 - 2.5e-05 24.3 0.0 0.0019 18.2 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF81628.1 - 2.8e-05 23.2 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGF81628.1 - 0.00043 19.9 0.1 0.00079 19.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF81628.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGF81628.1 - 0.0047 16.0 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 FTA2 PF13095.6 EGF81628.1 - 0.19 11.3 0.5 9.4 5.8 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Aminotran_5 PF00266.19 EGF81629.1 - 9.2e-47 159.8 0.0 1.1e-46 159.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Peptidase_M17 PF00883.21 EGF81630.1 - 6.3e-66 222.8 0.0 8.2e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Muskelin_N PF06588.11 EGF81631.1 - 5.2e-79 264.8 1.3 8.3e-79 264.1 1.3 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 EGF81631.1 - 1.9e-34 117.3 3.6 1.6e-09 37.8 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EGF81631.1 - 1.6e-20 72.9 6.5 0.00011 22.1 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF81631.1 - 2.4e-20 72.0 7.0 0.00081 19.6 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 EGF81631.1 - 1.9e-17 62.5 11.2 6.9e-06 25.5 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 EGF81631.1 - 4.2e-15 55.3 3.8 0.0023 17.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EGF81631.1 - 1.6e-14 53.2 4.5 1.2e-06 28.3 0.3 6.7 6 0 0 6 6 6 2 Kelch motif F5_F8_type_C PF00754.25 EGF81631.1 - 0.0085 16.2 0.9 0.028 14.5 0.0 2.4 3 0 0 3 3 3 1 F5/8 type C domain VWD PF00094.25 EGF81632.1 - 5.7e-05 23.4 0.2 5.7e-05 23.4 0.2 1.7 2 0 0 2 2 2 1 von Willebrand factor type D domain RGM_N PF06535.12 EGF81632.1 - 0.00096 19.4 0.1 0.00096 19.4 0.1 1.8 2 0 0 2 2 2 1 Repulsive guidance molecule (RGM) N-terminus EGF_2 PF07974.13 EGF81632.1 - 0.024 15.0 14.4 0.077 13.4 14.4 1.9 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGF81632.1 - 0.23 11.5 8.6 0.51 10.4 8.6 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EGF81632.1 - 1.3 9.4 13.7 0.39 11.0 9.1 2.3 2 0 0 2 2 2 0 EGF-like domain FAM72 PF14976.6 EGF81633.1 - 1.2e-55 187.6 4.2 1.4e-55 187.4 4.2 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 EGF81633.1 - 0.16 12.2 7.8 0.4 10.9 7.8 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Acetyltransf_3 PF13302.7 EGF81634.1 - 0.0013 19.4 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF81634.1 - 0.027 14.7 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pap_E4 PF02711.14 EGF81634.1 - 0.34 11.9 12.4 0.21 12.6 5.2 2.9 2 0 0 2 2 2 0 E4 protein FCH PF00611.23 EGF81635.1 - 1.6e-05 25.1 1.5 2.9e-05 24.3 0.1 2.2 2 2 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain PMSR PF01625.21 EGF81635.1 - 0.06 13.5 2.4 0.094 12.9 0.4 2.1 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase DUF3876 PF12992.7 EGF81636.1 - 0.0062 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3876) Na_H_Exchanger PF00999.21 EGF81637.1 - 2.2e-55 188.0 29.7 2.5e-55 187.8 29.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YwcE PF17368.2 EGF81637.1 - 0.03 15.0 2.0 0.03 15.0 2.0 3.4 3 0 0 3 3 3 0 Spore morphogenesis and germination YwcE SPC25 PF06703.11 EGF81637.1 - 0.046 13.5 1.3 0.15 11.8 0.2 2.4 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) YrhC PF14143.6 EGF81637.1 - 0.16 12.1 3.5 0.5 10.5 0.6 3.1 3 0 0 3 3 3 0 YrhC-like protein PNP_UDP_1 PF01048.20 EGF81638.1 - 2e-38 132.0 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Peroxin-22 PF12827.7 EGF81639.1 - 0.021 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family NosD PF05048.13 EGF81639.1 - 0.033 13.5 0.2 0.053 12.8 0.2 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Edc3_linker PF16598.5 EGF81639.1 - 6.6 7.5 12.6 23 5.7 6.5 3.0 2 1 1 3 3 3 0 Linker region of enhancer of mRNA-decapping protein 3 Peptidase_S41 PF03572.18 EGF81640.1 - 3e-10 39.9 0.0 6.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 CdiA_C PF18451.1 EGF81640.1 - 0.033 14.4 0.6 6.3 7.1 0.0 3.6 3 0 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain Lactamase_B PF00753.27 EGF81641.1 - 3.9e-07 30.3 0.0 6.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.25 EGF81642.1 - 9.4e-45 153.0 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81642.1 - 1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF81642.1 - 0.0064 15.3 0.0 0.0086 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF81642.1 - 0.07 12.4 0.1 0.19 11.0 0.1 1.7 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 EGF81644.1 - 2.3e-87 293.4 0.0 2.8e-87 293.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF81644.1 - 0.00037 21.4 0.0 0.0015 19.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DAO PF01266.24 EGF81645.1 - 1.8e-41 142.9 0.1 2.2e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGF81645.1 - 0.00082 19.4 0.4 0.011 15.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGF81645.1 - 0.0015 18.7 0.1 0.0045 17.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DPCD PF14913.6 EGF81646.1 - 2e-62 210.0 0.0 3.1e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 DPCD protein family SdiA-regulated PF06977.11 EGF81646.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 SdiA-regulated Steroid_dh PF02544.16 EGF81647.1 - 1.7e-39 135.2 1.0 1e-24 87.2 0.1 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGF81647.1 - 0.00047 19.7 0.6 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGF81647.1 - 0.0012 19.3 0.1 0.0012 19.3 0.1 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase Sorting_nexin PF03700.13 EGF81649.1 - 0.00088 19.8 1.7 0.017 15.7 0.1 2.8 3 0 0 3 3 3 1 Sorting nexin, N-terminal domain Yippee-Mis18 PF03226.14 EGF81650.1 - 5.8e-16 58.6 2.2 7.1e-16 58.3 2.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1771 PF08590.10 EGF81651.1 - 3.1e-13 49.9 10.8 5.6e-13 49.1 10.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGF81651.1 - 4.3e-07 30.2 0.8 7e-07 29.5 0.2 1.6 2 0 0 2 2 2 1 Smr domain TauD PF02668.16 EGF81652.1 - 1.9e-36 126.2 0.1 2.6e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGF81652.1 - 0.0012 19.4 1.0 0.0073 16.9 0.3 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGF81652.1 - 0.03 13.4 0.1 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 CsiD Ribosomal_L37ae PF01780.19 EGF81654.1 - 1e-41 140.9 10.8 1.1e-41 140.8 10.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGF81654.1 - 0.0063 16.5 1.6 0.01 15.8 1.6 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 EGF81654.1 - 0.023 14.8 1.7 0.033 14.3 1.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-BED PF02892.15 EGF81654.1 - 0.029 14.4 4.1 0.98 9.5 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger A2L_zn_ribbon PF08792.10 EGF81654.1 - 0.18 11.5 3.7 5.4 6.9 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 EGF81654.1 - 1.6 9.3 5.7 3 8.4 1.1 2.2 1 1 1 2 2 2 0 Zinc-finger double domain RNA_pol_Rpb8 PF03870.15 EGF81655.1 - 2.4e-54 183.3 0.0 2.7e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EGF81655.1 - 0.00061 19.8 0.3 0.066 13.3 0.2 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Tctex-1 PF03645.13 EGF81656.1 - 4.1e-22 78.3 0.0 4.9e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family zf-CCHC PF00098.23 EGF81657.1 - 0.0002 21.3 29.6 0.0052 16.8 4.4 4.1 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 EGF81657.1 - 0.00044 19.9 23.2 0.025 14.3 0.2 4.3 4 0 0 4 4 4 3 Zinc knuckle Spem1 PF15670.5 EGF81658.1 - 0.24 10.9 2.3 0.34 10.4 2.3 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 DnaJ PF00226.31 EGF81659.1 - 1.4e-21 76.3 2.7 5.1e-21 74.6 0.6 2.9 3 0 0 3 3 3 1 DnaJ domain TPR_2 PF07719.17 EGF81659.1 - 2e-20 71.2 17.9 1.1e-05 25.1 0.3 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGF81659.1 - 6.8e-18 63.7 17.8 1.7e-06 27.6 0.6 7.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGF81659.1 - 8.6e-15 55.1 5.2 9.5e-06 26.2 0.5 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGF81659.1 - 1.4e-14 53.5 11.6 0.0012 18.5 0.7 6.8 4 3 3 7 7 7 4 TPR repeat TPR_8 PF13181.6 EGF81659.1 - 3.5e-13 48.6 18.6 0.0016 18.5 0.0 7.1 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGF81659.1 - 7.5e-12 45.2 1.4 0.00041 20.4 0.1 4.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81659.1 - 8e-10 39.1 11.7 0.0089 16.5 0.6 5.6 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF81659.1 - 9.6e-09 35.0 10.2 0.18 12.2 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81659.1 - 1.1e-08 35.1 5.6 2.4 9.2 0.1 5.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81659.1 - 2e-07 31.2 9.9 0.19 12.1 0.1 5.5 3 2 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF81659.1 - 2.2e-06 27.8 14.8 0.17 12.1 0.1 5.4 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGF81659.1 - 0.00023 21.0 3.9 0.93 9.7 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF81659.1 - 0.00047 20.6 10.0 2 9.2 0.3 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGF81659.1 - 0.0017 17.6 3.8 0.29 10.3 0.2 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat YfdX PF10938.8 EGF81659.1 - 0.0024 17.8 7.3 4.2 7.3 0.0 4.5 3 1 1 5 5 5 1 YfdX protein SHNi-TPR PF10516.9 EGF81659.1 - 0.0031 16.9 0.2 4.9 6.7 0.1 3.4 2 0 0 2 2 2 1 SHNi-TPR DUF2251 PF10008.9 EGF81659.1 - 0.035 14.2 0.3 26 5.0 0.0 3.7 4 0 0 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2251) FlbT PF07378.11 EGF81659.1 - 0.07 13.2 1.1 2.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Flagellar protein FlbT TPR_20 PF14561.6 EGF81659.1 - 0.075 13.4 12.0 2.5 8.5 0.1 4.7 4 2 0 4 4 4 0 Tetratricopeptide repeat EF-hand_14 PF17959.1 EGF81659.1 - 0.097 13.0 1.2 2.4 8.6 0.0 3.1 2 1 0 2 2 2 0 EF-hand domain DUF5339 PF17274.2 EGF81659.1 - 0.28 12.0 0.0 0.28 12.0 0.0 3.1 3 0 0 3 3 2 0 Family of unknown function (DUF5339) DUF357 PF04010.13 EGF81659.1 - 0.37 10.9 4.8 41 4.3 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF357) BTAD PF03704.17 EGF81659.1 - 0.5 10.8 5.2 41 4.6 0.1 4.2 3 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 EGF81659.1 - 0.63 10.0 4.2 16 5.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGF81659.1 - 3.2 7.4 15.9 8.1 6.1 1.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain SnoaL PF07366.12 EGF81660.1 - 0.00078 19.2 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase JUPITER PF17054.5 EGF81660.1 - 0.0027 17.3 8.1 0.035 13.6 0.0 3.4 2 1 1 3 3 3 2 Microtubule-Associated protein Jupiter YlzJ PF14035.6 EGF81660.1 - 0.12 12.6 0.0 0.78 10.0 0.0 2.4 1 0 0 1 1 1 0 YlzJ-like protein BAG PF02179.16 EGF81662.1 - 3.4e-15 56.2 0.3 4.6e-15 55.8 0.3 1.2 1 0 0 1 1 1 1 BAG domain ARL2_Bind_BART PF11527.8 EGF81662.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART CCDC-167 PF15188.6 EGF81662.1 - 0.066 13.6 1.1 0.11 12.9 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 SPX PF03105.19 EGF81663.1 - 1.4 8.8 14.5 1.9 8.3 14.5 1.2 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 EGF81663.1 - 4.3 6.2 11.6 4.9 6.0 11.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Barwin PF00967.17 EGF81664.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Barwin family Trypan_PARP PF05887.11 EGF81664.1 - 0.02 14.9 17.6 0.054 13.5 17.4 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 EGF81664.1 - 0.043 13.0 4.4 0.058 12.6 4.4 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 TonB_N PF16031.5 EGF81664.1 - 0.06 13.9 22.5 0.1 13.2 22.5 1.3 1 0 0 1 1 1 0 TonB polyproline region SOG2 PF10428.9 EGF81664.1 - 1.7 7.8 12.3 1.8 7.7 12.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BES1_N PF05687.13 EGF81664.1 - 3.1 8.2 10.2 5.4 7.4 10.2 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Oxysterol_BP PF01237.18 EGF81666.1 - 1.4e-44 152.4 0.5 6.3e-42 143.7 0.5 2.9 1 1 0 1 1 1 1 Oxysterol-binding protein Sun2_CC2 PF18580.1 EGF81666.1 - 0.00024 21.3 0.5 0.00059 20.0 0.5 1.6 1 0 0 1 1 1 1 SUN2 coiled coil domain 2 MgpC PF05220.12 EGF81666.1 - 0.057 12.7 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 MgpC protein precursor EF-hand_7 PF13499.6 EGF81667.1 - 0.043 14.3 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair Oxidored_q4 PF00507.19 EGF81667.1 - 0.094 12.9 1.0 0.16 12.1 1.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 RhoGAP PF00620.27 EGF81668.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RasGAP PF00616.19 EGF81668.1 - 0.15 11.8 2.2 0.37 10.5 2.1 1.7 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Peptidase_M1 PF01433.20 EGF81669.1 - 8.7e-85 283.7 1.4 1.3e-84 283.1 0.6 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGF81669.1 - 2.9e-56 191.3 2.3 4.4e-56 190.7 1.1 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGF81669.1 - 1.3e-50 172.2 2.5 3.2e-50 170.9 2.5 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EGF81669.1 - 0.00013 22.0 0.2 0.00028 20.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) DUF4695 PF15766.5 EGF81669.1 - 0.012 15.8 0.7 0.032 14.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF3458 PF11940.8 EGF81669.1 - 0.11 13.0 0.3 0.81 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold MARVEL PF01284.23 EGF81670.1 - 0.26 11.3 11.4 0.67 10.0 11.4 1.7 1 1 0 1 1 1 0 Membrane-associating domain ST7 PF04184.12 EGF81672.1 - 0.14 10.6 3.2 0.17 10.3 3.2 1.1 1 0 0 1 1 1 0 ST7 protein AAA_6 PF12774.7 EGF81673.1 - 7.1e-157 521.5 0.0 2.8e-156 519.5 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF81673.1 - 2.8e-143 477.8 10.7 2.8e-143 477.8 10.7 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGF81673.1 - 6.3e-110 366.6 2.6 1e-108 362.6 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGF81673.1 - 1e-107 359.9 0.0 2.3e-107 358.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGF81673.1 - 2.7e-88 294.8 1.0 2.7e-88 294.8 1.0 3.2 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF81673.1 - 1.4e-84 282.1 0.0 1e-82 276.0 0.0 3.2 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF81673.1 - 1.9e-63 213.2 0.0 7.1e-63 211.3 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF81673.1 - 9e-59 199.2 7.1 9e-59 199.2 7.1 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGF81673.1 - 1.1e-47 161.1 0.0 1e-44 151.4 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGF81673.1 - 4.5e-32 110.8 0.2 2.7e-31 108.3 0.2 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGF81673.1 - 8.3e-21 74.1 0.1 4.1e-20 71.9 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGF81673.1 - 1.8e-17 63.7 0.0 2.6e-05 24.2 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF81673.1 - 2e-05 25.0 0.1 2.1 8.7 0.0 5.1 5 1 1 6 6 5 2 AAA ATPase domain AAA PF00004.29 EGF81673.1 - 6.1e-05 23.4 0.2 2.9 8.3 0.1 4.8 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF81673.1 - 0.00032 21.2 0.1 0.81 10.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGF81673.1 - 0.0026 18.0 0.0 3.8 7.8 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGF81673.1 - 0.0045 16.7 0.1 1.3 8.8 0.2 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGF81673.1 - 0.0048 17.1 0.0 2 8.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EGF81673.1 - 0.0069 15.5 0.0 0.2 10.7 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EGF81673.1 - 0.0086 16.4 0.1 13 6.2 0.0 4.4 4 0 0 4 4 3 0 RNA helicase AAA_24 PF13479.6 EGF81673.1 - 0.026 14.2 0.6 10 5.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain PI3K_P85_iSH2 PF16454.5 EGF81673.1 - 0.2 11.3 13.9 1.7 8.3 1.3 4.6 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF853 PF05872.12 EGF81673.1 - 0.32 9.5 2.2 37 2.7 0.0 3.9 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF853) Vps5 PF09325.10 EGF81673.1 - 2 7.9 11.0 0.084 12.4 1.3 3.5 3 0 0 3 3 3 0 Vps5 C terminal like ATG16 PF08614.11 EGF81673.1 - 3.1 8.0 17.3 2.3 8.4 6.0 3.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Med31 PF05669.12 EGF81674.1 - 2e-36 123.9 9.9 2.1e-36 123.8 9.9 1.0 1 0 0 1 1 1 1 SOH1 NDUF_B8 PF05821.11 EGF81675.1 - 9e-09 35.4 1.2 1.6e-08 34.7 1.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Abi_C PF14355.6 EGF81676.1 - 0.036 14.2 0.5 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Abortive infection C-terminus TPR_MLP1_2 PF07926.12 EGF81677.1 - 0.022 14.8 6.2 0.16 12.1 6.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 EGF81677.1 - 0.037 14.2 1.7 0.096 12.8 1.7 1.7 1 0 0 1 1 1 0 Tropomyosin like FapA PF03961.13 EGF81677.1 - 0.046 12.3 4.0 0.066 11.8 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliJ PF02050.16 EGF81677.1 - 0.052 13.8 1.8 0.091 13.0 1.8 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein GAS PF13851.6 EGF81677.1 - 0.21 10.9 5.0 0.45 9.8 5.0 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rho_Binding PF08912.11 EGF81677.1 - 0.44 11.4 3.1 14 6.6 0.1 2.7 2 0 0 2 2 2 0 Rho Binding End3 PF12761.7 EGF81677.1 - 4.9 7.3 8.8 4.7 7.3 6.5 2.0 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Na_H_Exchanger PF00999.21 EGF81678.1 - 3.8e-73 246.5 37.7 4.4e-73 246.3 37.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF525 PF04379.14 EGF81679.1 - 4.9e-11 42.7 0.1 2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 ApaG domain DUF244 PF03112.14 EGF81679.1 - 0.031 14.1 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DLH PF01738.18 EGF81681.1 - 3.8e-30 105.1 0.0 4.8e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGF81681.1 - 0.008 16.1 0.0 1.1 9.1 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EGF81681.1 - 0.0084 15.7 0.0 0.25 10.9 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EGF81681.1 - 0.022 14.0 0.0 1.9 7.7 0.0 2.4 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGF81681.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF3223 PF11523.8 EGF81681.1 - 0.049 14.5 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) FSH1 PF03959.13 EGF81681.1 - 0.052 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 EGF81681.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ABC_membrane PF00664.23 EGF81682.1 - 2.5e-66 224.2 33.7 1.4e-38 133.1 10.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF81682.1 - 2.3e-55 186.9 0.0 1.9e-32 112.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 EGF81682.1 - 5.8e-07 29.6 4.1 0.0058 16.7 0.3 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF81682.1 - 5.9e-06 26.3 0.1 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGF81682.1 - 6.4e-06 26.3 10.0 8.6e-05 22.7 0.5 4.0 4 0 0 4 4 4 1 Dynamin family SMC_N PF02463.19 EGF81682.1 - 1.7e-05 24.3 8.8 0.44 9.9 0.2 3.7 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGF81682.1 - 1.8e-05 24.4 0.6 0.24 11.2 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGF81682.1 - 0.00054 19.3 0.8 1.8 7.8 0.1 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_16 PF13191.6 EGF81682.1 - 0.0007 20.0 0.0 1.1 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 EGF81682.1 - 0.0012 19.0 5.2 0.03 14.4 0.2 2.9 3 0 0 3 3 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EGF81682.1 - 0.0031 16.9 0.2 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.6 EGF81682.1 - 0.0032 18.0 2.0 1.2 9.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain AIG1 PF04548.16 EGF81682.1 - 0.0042 16.4 0.8 1.2 8.4 0.1 2.6 2 0 0 2 2 2 1 AIG1 family AAA_7 PF12775.7 EGF81682.1 - 0.0046 16.5 0.4 0.91 9.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 EGF81682.1 - 0.0058 16.4 0.2 1.4 8.5 0.2 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGF81682.1 - 0.0058 16.9 0.1 6.8 7.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGF81682.1 - 0.011 14.7 0.8 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EGF81682.1 - 0.016 15.0 1.4 0.92 9.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 EGF81682.1 - 0.02 14.0 0.9 0.083 11.9 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EGF81682.1 - 0.02 14.6 0.1 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGF81682.1 - 0.022 14.6 3.8 2.7 7.7 0.0 3.3 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EGF81682.1 - 0.024 15.2 0.1 0.92 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EGF81682.1 - 0.029 13.2 1.1 1.1 8.0 0.3 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class T2SSE PF00437.20 EGF81682.1 - 0.03 13.4 0.1 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4574 PF15141.6 EGF81682.1 - 0.032 14.1 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Roc PF08477.13 EGF81682.1 - 0.051 13.8 0.7 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 EGF81682.1 - 0.097 12.6 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PRK PF00485.18 EGF81682.1 - 0.1 12.3 1.1 11 5.7 0.3 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 EGF81682.1 - 0.12 12.0 0.1 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 EGF81682.1 - 0.14 12.2 0.0 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EGF81682.1 - 0.14 11.7 1.0 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EGF81682.1 - 0.15 11.2 1.3 2.8 7.1 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 EGF81682.1 - 0.15 11.8 1.0 0.84 9.4 0.1 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase MeaB PF03308.16 EGF81682.1 - 0.21 10.5 1.2 16 4.4 0.2 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EGF81682.1 - 0.24 11.2 1.5 4.7 6.9 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arm-DNA-bind_4 PF14657.6 EGF81684.1 - 0.039 13.7 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain DUF3422 PF11902.8 EGF81684.1 - 0.069 12.3 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF1283 PF06932.11 EGF81684.1 - 0.099 12.9 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) Asp PF00026.23 EGF81685.1 - 2.6e-09 36.9 0.0 1.5e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 EGF81685.1 - 0.032 14.8 0.1 8.9 7.0 0.1 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGF81685.1 - 0.046 14.4 0.7 0.49 11.1 0.2 2.3 2 0 0 2 2 2 0 Aspartyl protease DUF4246 PF14033.6 EGF81687.1 - 1.1e-80 272.0 0.0 1.4e-80 271.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Phage-A118_gp45 PF10653.9 EGF81688.1 - 0.14 12.2 0.3 0.37 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 DUF3560 PF12083.8 EGF81689.1 - 0.064 13.4 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) MetOD2 PF18548.1 EGF81691.1 - 0.034 14.2 1.1 0.11 12.7 1.0 1.9 1 1 0 1 1 1 0 Metanogen output domain 2 zf_C2H2_13 PF18508.1 EGF81692.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger domain ETRAMP PF09716.10 EGF81693.1 - 1.9 8.6 4.5 0.79 9.8 0.2 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RasGAP PF00616.19 EGF81694.1 - 2.3e-30 105.9 0.1 2.1e-20 73.4 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGF81694.1 - 3.4e-14 53.2 1.0 8.9e-14 51.8 1.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGF81694.1 - 2.3e-05 24.2 0.8 5.1e-05 23.0 0.8 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain IRK_N PF08466.10 EGF81694.1 - 0.12 12.6 0.0 23 5.2 0.0 2.7 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal p450 PF00067.22 EGF81695.1 - 2.4e-65 221.1 0.3 1.3e-61 208.8 0.7 2.0 1 1 1 2 2 2 2 Cytochrome P450 AAA PF00004.29 EGF81696.1 - 3.9e-42 143.8 0.0 8.1e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGF81696.1 - 4.2e-27 93.9 0.0 1.8e-26 91.9 0.0 2.2 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGF81696.1 - 6.5e-24 83.8 4.5 1.5e-23 82.6 4.5 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGF81696.1 - 1.4e-07 31.2 0.0 5.8e-07 29.2 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EGF81696.1 - 6.5e-06 26.6 0.1 0.00068 20.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGF81696.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGF81696.1 - 3e-05 23.8 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGF81696.1 - 4.8e-05 23.4 0.0 0.0002 21.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGF81696.1 - 7.8e-05 23.0 0.0 0.0023 18.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGF81696.1 - 0.00011 22.3 0.8 0.0015 18.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 EGF81696.1 - 0.00011 21.5 0.1 0.00042 19.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 EGF81696.1 - 0.00041 20.7 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 EGF81696.1 - 0.00064 19.0 0.0 0.0014 17.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGF81696.1 - 0.002 17.9 0.4 0.0094 15.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGF81696.1 - 0.0044 17.6 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNase_H2_suC PF08615.11 EGF81696.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AAA_2 PF07724.14 EGF81696.1 - 0.0077 16.4 0.0 0.039 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGF81696.1 - 0.0089 16.2 0.0 0.028 14.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain USP8_dimer PF08969.11 EGF81696.1 - 0.009 16.2 8.0 0.021 15.0 8.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain ATPase PF06745.13 EGF81696.1 - 0.009 15.4 0.3 7.8 5.8 0.0 3.2 2 1 1 3 3 3 0 KaiC Parvo_NS1 PF01057.17 EGF81696.1 - 0.0091 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EGF81696.1 - 0.013 15.9 0.4 0.15 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGF81696.1 - 0.013 15.0 0.0 0.78 9.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 EGF81696.1 - 0.018 15.0 0.0 0.21 11.5 0.0 2.6 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EGF81696.1 - 0.023 14.4 0.0 0.079 12.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGF81696.1 - 0.026 13.9 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3543 PF12063.8 EGF81696.1 - 0.032 13.6 0.2 0.058 12.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) CPT PF07931.12 EGF81696.1 - 0.065 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 EGF81696.1 - 0.088 13.3 0.1 0.44 11.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 EGF81696.1 - 0.092 12.5 0.1 7.4 6.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGF81696.1 - 0.094 12.2 0.0 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 EGF81696.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Torsin PhoH PF02562.16 EGF81696.1 - 0.13 11.7 0.1 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EGF81696.1 - 0.19 11.6 3.8 1.4 8.8 0.0 3.1 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea Vfa1 PF08432.10 EGF81696.1 - 7.2 6.9 12.3 12 6.2 12.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 4HBT PF03061.22 EGF81697.1 - 1.9e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Thioredoxin PF00085.20 EGF81699.1 - 2.9e-29 101.1 0.3 3e-29 101.0 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGF81699.1 - 1.3e-05 25.4 0.0 1.7e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGF81699.1 - 5.8e-05 23.5 0.2 0.00055 20.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGF81699.1 - 8.4e-05 22.5 0.0 8.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGF81699.1 - 0.00026 20.7 0.0 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGF81699.1 - 0.00043 19.7 0.2 0.00053 19.4 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGF81699.1 - 0.0091 16.2 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EGF81699.1 - 0.048 13.4 0.2 0.061 13.0 0.2 1.4 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 EGF81699.1 - 0.064 13.1 0.1 0.071 12.9 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 EGF81699.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin zf-CCHC PF00098.23 EGF81700.1 - 2.9e-06 27.1 1.2 5.1e-06 26.3 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle CTD_bind PF04818.13 EGF81700.1 - 0.0022 18.8 0.2 0.0053 17.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-CCHC_4 PF14392.6 EGF81700.1 - 0.025 14.3 0.7 0.052 13.3 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2815 PF10991.8 EGF81700.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) Dpy-30 PF05186.13 EGF81701.1 - 4.7e-07 29.4 0.6 0.025 14.3 0.1 2.2 2 0 0 2 2 2 2 Dpy-30 motif Ribosomal_S19 PF00203.21 EGF81702.1 - 8.6e-23 80.0 0.1 1.1e-22 79.7 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S19 Mannosyl_trans3 PF11051.8 EGF81704.1 - 5.3e-45 153.9 0.0 7.7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Peptidase_M36 PF02128.15 EGF81705.1 - 3.3e-123 411.5 7.4 3.6e-123 411.4 7.4 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 EGF81705.1 - 0.027 14.1 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like CHZ PF09649.10 EGF81706.1 - 2.3e-12 46.2 0.2 2.3e-12 46.2 0.2 2.2 2 1 0 2 2 1 1 Histone chaperone domain CHZ Merozoite_SPAM PF07133.11 EGF81706.1 - 0.03 14.3 21.0 0.04 13.9 21.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 EGF81706.1 - 0.11 10.8 23.5 0.12 10.7 23.5 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 EGF81706.1 - 0.17 11.3 25.7 0.18 11.1 25.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PNISR PF15996.5 EGF81706.1 - 0.38 11.0 22.8 0.49 10.7 22.8 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR ORC6 PF05460.13 EGF81706.1 - 0.85 8.8 19.2 1.1 8.5 19.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nop14 PF04147.12 EGF81706.1 - 1 7.5 33.8 1.1 7.3 33.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGF81706.1 - 1.4 6.9 34.3 1.8 6.5 34.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_S64 PF08192.11 EGF81706.1 - 2 6.8 18.3 2.2 6.7 18.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mitofilin PF09731.9 EGF81706.1 - 3.1 6.5 18.9 3.4 6.4 18.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AIM3 PF17096.5 EGF81706.1 - 3.7 8.6 28.1 10 7.1 22.1 2.7 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 3 TRAP_alpha PF03896.16 EGF81706.1 - 3.8 6.6 11.6 4.7 6.3 11.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 EGF81706.1 - 4.9 6.4 35.5 5.5 6.2 35.5 1.3 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EGF81706.1 - 5.4 5.4 16.4 5.5 5.4 16.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cellulose_synt PF03552.14 EGF81706.1 - 5.7 5.3 5.5 6.2 5.2 5.5 1.1 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.17 EGF81706.1 - 5.8 5.6 19.0 6.8 5.3 19.0 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 EGF81706.1 - 7.7 6.3 30.2 8.5 6.2 30.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4637 PF15470.6 EGF81706.1 - 8.5 6.1 21.8 7.2 6.3 20.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Raftlin PF15250.6 EGF81706.1 - 8.8 5.0 15.1 9.6 4.8 15.1 1.1 1 0 0 1 1 1 0 Raftlin zf-RanBP PF00641.18 EGF81708.1 - 3e-07 29.6 9.6 4.6e-07 29.0 9.6 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others PEPCK_GTP PF00821.18 EGF81708.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain EST1_DNA_bind PF10373.9 EGF81709.1 - 1.3e-11 44.5 2.3 4.3e-10 39.6 1.3 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EGF81709.1 - 1.5e-11 45.1 0.9 8.2e-11 42.7 0.9 2.3 1 1 0 1 1 1 1 Telomerase activating protein Est1 SNARE PF05739.19 EGF81710.1 - 0.0018 18.2 0.2 0.034 14.1 0.0 2.7 3 0 0 3 3 3 1 SNARE domain DUF1043 PF06295.12 EGF81710.1 - 0.015 15.3 1.9 0.015 15.3 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF5089 PF17002.5 EGF81710.1 - 0.055 13.3 3.1 0.094 12.6 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) LPP PF04728.13 EGF81710.1 - 0.16 12.4 2.0 1.3 9.5 2.0 2.5 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EGF81710.1 - 0.48 10.7 5.6 0.11 12.8 2.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EMP24_GP25L PF01105.24 EGF81710.1 - 1.1 9.1 4.1 0.32 10.9 0.8 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD 4HB_MCP_1 PF12729.7 EGF81710.1 - 1.2 8.6 8.7 3.5 7.1 1.4 3.1 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction RNA_pol_Rpb2_6 PF00562.28 EGF81711.1 - 8.7e-125 416.8 0.0 2.1e-124 415.6 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGF81711.1 - 4.7e-54 183.0 0.0 8.2e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGF81711.1 - 1.8e-31 108.4 0.2 5.9e-31 106.7 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGF81711.1 - 4.7e-25 88.3 0.0 9.6e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGF81711.1 - 6e-25 87.3 1.5 1.4e-24 86.1 1.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGF81711.1 - 1.5e-14 53.9 0.5 4.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGF81711.1 - 2.8e-08 34.2 0.1 1.5e-07 31.9 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Chitin_synth_2 PF03142.15 EGF81712.1 - 7.2e-206 684.9 1.5 9.6e-206 684.5 1.5 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGF81712.1 - 6.4e-16 58.9 0.0 4.3e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF81712.1 - 1.3e-11 44.8 6.8 3.2e-11 43.5 6.8 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGF81712.1 - 5.1e-07 29.7 0.0 0.00044 20.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGF81712.1 - 0.0024 17.4 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Herpes_LMP1 PF05297.11 EGF81712.1 - 0.032 13.4 0.5 0.043 13.0 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TFIID-18kDa PF02269.16 EGF81713.1 - 2e-25 88.6 1.0 4.3e-25 87.5 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EGF81713.1 - 1.1e-05 25.5 1.1 1.3e-05 25.1 0.1 1.7 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Pannexin_like PF12534.8 EGF81713.1 - 0.025 13.7 0.2 0.034 13.3 0.2 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF1449 PF07290.11 EGF81714.1 - 1.4 8.5 7.7 5.5 6.6 7.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1449) LRRFIP PF09738.9 EGF81715.1 - 0.0045 16.5 3.7 0.0069 15.9 3.7 1.2 1 0 0 1 1 1 1 LRRFIP family SlyX PF04102.12 EGF81715.1 - 0.097 13.3 4.0 1.7 9.3 3.3 2.3 1 1 1 2 2 2 0 SlyX YebO PF13974.6 EGF81715.1 - 0.3 11.2 2.8 0.6 10.2 2.8 1.6 1 1 0 1 1 1 0 YebO-like protein AAA_16 PF13191.6 EGF81716.1 - 0.019 15.4 0.0 0.055 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF4246 PF14033.6 EGF81717.1 - 3.4e-95 319.8 0.0 4.8e-95 319.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) TMPIT PF07851.13 EGF81718.1 - 0.0016 17.7 3.3 0.0016 17.7 3.3 1.5 2 0 0 2 2 2 1 TMPIT-like protein DUF2076 PF09849.9 EGF81718.1 - 0.068 13.2 7.9 0.066 13.3 5.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TelA PF05816.11 EGF81718.1 - 0.27 10.2 9.3 0.45 9.5 9.3 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DUF4246 PF14033.6 EGF81720.1 - 7.2e-83 279.2 0.1 9.2e-83 278.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) MORN PF02493.20 EGF81721.1 - 4.4e-10 38.8 8.1 1e-05 25.1 2.8 3.7 4 0 0 4 4 4 2 MORN repeat Sen15 PF09631.10 EGF81721.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Sen15 protein WD40 PF00400.32 EGF81722.1 - 2.3e-16 59.8 4.2 0.00012 22.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81722.1 - 4.3e-12 46.2 0.0 0.059 13.7 0.0 4.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF81722.1 - 0.00036 19.6 0.0 2.6 6.9 0.0 3.3 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGF81722.1 - 0.029 13.1 0.1 0.92 8.2 0.0 2.7 2 1 0 3 3 3 0 Nup133 N terminal like AhpC-TSA PF00578.21 EGF81723.1 - 1.6e-34 118.5 0.0 2.3e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EGF81723.1 - 1.2e-14 53.8 0.0 2.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EGF81723.1 - 9.2e-12 44.9 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EGF81723.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Plant_zn_clust PF10533.9 EGF81723.1 - 0.041 13.9 0.4 0.077 13.0 0.4 1.5 1 0 0 1 1 1 0 Plant zinc cluster domain SIR2 PF02146.17 EGF81724.1 - 5.4e-53 179.5 0.0 7.3e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family S1-P1_nuclease PF02265.16 EGF81726.1 - 7.5e-60 202.9 0.8 8.7e-60 202.6 0.8 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF953 PF06110.11 EGF81728.1 - 3.4e-21 75.1 0.0 3.7e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) LIX1 PF14954.6 EGF81728.1 - 0.058 12.7 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 Limb expression 1 Glyco_trans_2_3 PF13632.6 EGF81729.1 - 7.7e-14 52.1 2.9 7.7e-14 52.1 2.9 1.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF81729.1 - 1.5e-05 25.0 0.0 1.9e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 APG5 PF04106.12 EGF81730.1 - 1.1e-32 113.4 0.0 1.8e-30 106.2 0.0 2.0 1 1 0 1 1 1 1 Autophagy protein Apg5 Rad52_Rad22 PF04098.15 EGF81731.1 - 1.4e-54 184.1 0.0 1.6e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Mito_carr PF00153.27 EGF81732.1 - 7.4e-56 186.1 3.9 1.5e-19 69.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 EGF81732.1 - 0.023 14.8 0.1 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 PrcB C-terminal HMD PF03201.16 EGF81732.1 - 0.027 14.7 0.0 7.4 6.9 0.0 3.2 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase MtrF PF09472.10 EGF81732.1 - 0.081 12.3 0.3 0.47 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Flavin_Reduct PF01613.18 EGF81733.1 - 0.00032 20.8 0.7 0.00039 20.5 0.7 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DNA_primase_lrg PF04104.14 EGF81734.1 - 7.5e-78 261.6 0.0 9.4e-78 261.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit FYVE PF01363.21 EGF81735.1 - 2.1e-13 50.2 7.6 5e-13 49.0 7.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EGF81735.1 - 0.069 13.3 10.1 0.16 12.1 10.1 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger DUF2203 PF09969.9 EGF81735.1 - 2.7 8.8 15.7 0.036 14.8 2.6 3.5 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 EGF81735.1 - 6.6 5.2 10.8 2.3 6.7 7.4 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A WD40 PF00400.32 EGF81736.1 - 1.2e-32 111.4 4.5 2.2e-06 28.3 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PRP4 PF08799.11 EGF81736.1 - 4.5e-12 45.3 4.3 1.1e-11 44.1 4.3 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGF81736.1 - 2e-11 44.0 0.0 0.0014 18.8 0.1 5.6 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF81736.1 - 0.0049 16.8 0.1 0.48 10.3 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGF81736.1 - 0.019 13.9 0.0 5 6.0 0.0 3.1 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SH3_1 PF00018.28 EGF81737.1 - 1.9e-36 123.4 5.9 3.4e-14 52.2 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 EGF81737.1 - 3.9e-33 113.1 5.4 5.2e-13 48.6 0.2 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 EGF81737.1 - 1.9e-27 94.9 0.0 3.4e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EGF81737.1 - 1.8e-26 91.6 0.0 3.4e-08 33.0 0.1 3.8 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 EGF81737.1 - 0.00013 22.0 0.3 0.44 10.7 0.1 4.0 3 1 0 3 3 3 2 SH3 domain SAM_4 PF18017.1 EGF81737.1 - 0.00033 20.6 0.2 0.00099 19.0 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4957 PF16318.5 EGF81737.1 - 0.029 14.3 2.6 0.081 12.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4957) Ferric_reduct PF01794.19 EGF81738.1 - 3e-13 50.0 9.6 3e-13 50.0 9.6 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGF81738.1 - 3.8e-10 39.8 0.1 8.1e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGF81738.1 - 2.4e-09 37.5 0.0 3.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain TLD PF07534.16 EGF81739.1 - 5.4e-28 98.0 0.1 7.9e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 TLD RRM_8 PF11835.8 EGF81740.1 - 0.04 14.1 0.1 0.16 12.2 0.1 2.0 1 0 0 1 1 1 0 RRM-like domain Pfg27 PF09216.10 EGF81740.1 - 0.12 12.2 0.0 0.44 10.4 0.0 1.9 1 0 0 1 1 1 0 Pfg27 Mitofilin PF09731.9 EGF81740.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PPR_3 PF13812.6 EGF81740.1 - 0.13 12.3 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain ANAPC4_WD40 PF12894.7 EGF81741.1 - 0.0019 18.4 0.3 0.098 13.0 0.1 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PhoLip_ATPase_C PF16212.5 EGF81742.1 - 1.6e-75 254.1 24.6 1.6e-75 254.1 24.6 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGF81742.1 - 4.5e-25 87.1 4.5 1.8e-24 85.2 4.5 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGF81742.1 - 9.4e-12 44.9 0.0 2.7e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGF81742.1 - 2.9e-11 44.1 0.3 0.00032 21.1 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGF81742.1 - 1.6e-05 24.5 0.0 6e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGF81742.1 - 0.00038 20.3 0.1 0.0021 17.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5404 PF17397.2 EGF81743.1 - 0.067 13.3 0.7 0.82 9.8 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5404) Pro_isomerase PF00160.21 EGF81744.1 - 1.7e-47 161.6 0.8 2e-47 161.4 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CR6_interact PF10147.9 EGF81745.1 - 0.00013 21.8 3.4 0.0002 21.1 3.4 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mitoc_mL59 PF18126.1 EGF81745.1 - 0.0018 18.5 3.2 0.015 15.6 1.9 2.1 1 1 1 2 2 2 1 Mitochondrial ribosomal protein mL59 TPH PF13868.6 EGF81746.1 - 2.9e-72 243.1 125.6 2.9e-72 243.1 125.6 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain rve_3 PF13683.6 EGF81746.1 - 6.4 6.6 7.9 3.6 7.4 4.1 2.7 2 0 0 2 2 2 0 Integrase core domain Metallophos PF00149.28 EGF81747.1 - 8.9e-13 49.2 0.1 1.2e-12 48.8 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EGF81747.1 - 0.00054 18.4 0.1 0.0065 14.8 0.0 2.0 2 0 0 2 2 2 2 Firmicute fructose-1,6-bisphosphatase Ras PF00071.22 EGF81748.1 - 5.2e-57 192.0 0.6 5.9e-57 191.8 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF81748.1 - 2.3e-20 73.0 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF81748.1 - 3.2e-08 33.2 0.2 3.6e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF81748.1 - 0.00025 20.7 0.3 0.00069 19.2 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF81748.1 - 0.00048 20.2 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF81748.1 - 0.00052 20.0 1.9 0.26 11.2 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EGF81748.1 - 0.027 13.7 0.1 0.29 10.3 0.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit Mito_carr PF00153.27 EGF81749.1 - 9.8e-66 217.7 2.2 3.1e-22 78.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGF81749.1 - 0.12 12.6 0.0 17 5.7 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase WD40 PF00400.32 EGF81750.1 - 6.4e-07 30.0 3.4 0.00018 22.2 0.1 4.5 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81750.1 - 1.3e-06 28.5 0.0 0.034 14.4 0.0 4.0 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGF81750.1 - 0.00086 17.9 0.0 0.02 13.4 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF2415 PF10313.9 EGF81750.1 - 0.0039 17.1 0.1 0.0098 15.8 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Str_synth PF03088.16 EGF81750.1 - 0.027 14.6 0.0 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 Strictosidine synthase PhoPQ_related PF10142.9 EGF81751.1 - 0.13 10.9 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein LIG3_BRCT PF16759.5 EGF81751.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain CBFD_NFYB_HMF PF00808.23 EGF81752.1 - 4.7e-29 100.5 0.4 6e-29 100.1 0.4 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGF81752.1 - 4.3e-07 30.3 0.1 5.6e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGF81752.1 - 3.6e-05 23.8 0.0 4.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EGF81752.1 - 0.0054 16.7 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-X PF09415.10 EGF81752.1 - 0.017 15.4 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Bromo_TP PF07524.13 EGF81752.1 - 0.075 13.0 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Bromodomain associated TPR_2 PF07719.17 EGF81753.1 - 2.2e-19 67.9 0.5 0.001 19.0 0.0 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGF81753.1 - 3.7e-19 67.7 1.5 3.6e-06 26.6 0.0 5.1 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGF81753.1 - 4e-15 56.2 0.0 1.3e-06 29.0 0.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF81753.1 - 3.6e-13 49.0 1.7 8.4e-05 22.2 0.0 4.5 2 2 2 4 4 4 4 TPR repeat TPR_12 PF13424.6 EGF81753.1 - 7.7e-12 45.3 0.2 6e-06 26.5 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81753.1 - 1.9e-11 43.2 0.7 0.0086 16.2 0.0 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGF81753.1 - 5.9e-11 42.0 0.1 0.00016 21.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81753.1 - 7.6e-06 26.3 0.1 0.042 14.7 0.0 4.1 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81753.1 - 2.1e-05 24.9 0.3 0.0023 18.4 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF81753.1 - 5.9e-05 22.8 0.2 0.47 10.6 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 EGF81753.1 - 0.00098 18.6 0.4 0.0043 16.5 0.2 1.8 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_20 PF14561.6 EGF81753.1 - 0.015 15.6 0.0 4.3 7.7 0.0 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF81753.1 - 0.028 13.8 0.2 0.077 12.4 0.2 1.7 1 1 0 1 1 1 0 MalT-like TPR region TPR_6 PF13174.6 EGF81753.1 - 0.031 14.9 0.0 71 4.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec34 PF04136.15 EGF81754.1 - 3.5e-43 147.0 1.8 3.5e-43 147.0 1.8 3.1 4 0 0 4 4 4 1 Sec34-like family G-patch PF01585.23 EGF81754.1 - 1.1e-14 54.0 0.8 2.1e-14 53.1 0.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF81754.1 - 0.00032 20.7 0.7 0.00032 20.7 0.7 2.1 2 0 0 2 2 2 1 G-patch domain CDC45 PF02724.14 EGF81754.1 - 0.0016 16.8 3.3 0.0027 16.1 3.3 1.3 1 0 0 1 1 1 1 CDC45-like protein LINES_N PF14694.6 EGF81755.1 - 3.1e-13 49.9 4.1 3.1e-13 49.9 4.1 2.3 3 0 0 3 3 3 1 Lines N-terminus MitMem_reg PF13012.6 EGF81755.1 - 0.068 13.6 0.3 6.9 7.1 0.0 3.2 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Pox_vIL-18BP PF05566.12 EGF81755.1 - 0.13 12.5 0.4 64 3.8 0.0 3.1 2 1 1 3 3 3 0 Orthopoxvirus interleukin 18 binding protein MMS1_N PF10433.9 EGF81757.1 - 9.5e-76 255.4 0.9 1.9e-75 254.4 0.9 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGF81757.1 - 5.1e-27 95.0 0.4 1.1e-26 94.0 0.4 1.5 1 0 0 1 1 1 1 CPSF A subunit region RNA_pol_3_Rpc31 PF11705.8 EGF81758.1 - 6.2e-25 88.8 0.8 9.8e-25 88.1 0.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 EGF81758.1 - 9.3 5.3 8.6 11 5.0 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAT1 PF09770.9 EGF81761.1 - 8.2e-63 213.0 0.2 8.2e-63 213.0 0.2 5.4 1 1 4 6 6 6 3 Topoisomerase II-associated protein PAT1 AAA_6 PF12774.7 EGF81762.1 - 4.5e-61 206.6 1.6 2e-60 204.5 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF81762.1 - 6.2e-53 180.3 5.7 6.2e-53 180.3 5.7 3.4 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 EGF81762.1 - 5.7e-26 91.1 2.7 1.1e-19 70.6 0.2 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 EGF81762.1 - 2.9e-25 89.2 1.9 2.5e-24 86.0 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA PF00004.29 EGF81762.1 - 1.4e-10 41.7 0.0 0.00015 22.2 0.0 5.5 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF81762.1 - 2.3e-09 37.9 0.0 5.5e-05 23.6 0.0 5.1 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EGF81762.1 - 3.5e-09 37.0 6.4 2.9e-06 27.6 0.0 6.2 6 0 0 6 6 6 1 AAA domain F-box-like PF12937.7 EGF81762.1 - 2.5e-07 30.5 1.6 8.6e-07 28.8 1.6 2.0 1 0 0 1 1 1 1 F-box-like ATPase_2 PF01637.18 EGF81762.1 - 3.9e-07 30.2 0.3 0.00011 22.3 0.0 4.5 4 0 0 4 4 4 1 ATPase domain predominantly from Archaea Dynein_AAA_lid PF17852.1 EGF81762.1 - 1e-06 28.9 3.2 1.2e-06 28.6 0.2 2.8 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF81762.1 - 1.7e-05 24.1 0.1 3.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor F-box PF00646.33 EGF81762.1 - 2.9e-05 23.8 6.2 4.7e-05 23.1 4.2 2.7 2 0 0 2 2 1 1 F-box domain DUF4062 PF13271.6 EGF81762.1 - 3.9e-05 23.9 0.0 0.00019 21.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_8 PF12780.7 EGF81762.1 - 0.0002 20.8 4.7 0.00031 20.2 1.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 NACHT PF05729.12 EGF81762.1 - 0.00025 21.0 0.0 0.09 12.7 0.0 3.9 3 0 0 3 3 3 1 NACHT domain ANAPC4_WD40 PF12894.7 EGF81762.1 - 0.00069 19.9 0.1 0.0065 16.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_5 PF07728.14 EGF81762.1 - 0.0018 18.3 0.0 18 5.3 0.0 5.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGF81762.1 - 0.0021 17.8 0.1 2.4 7.8 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EGF81762.1 - 0.027 15.0 0.6 3.1 8.4 0.0 3.9 3 0 0 3 3 2 0 AAA domain F-box_4 PF15966.5 EGF81762.1 - 0.032 14.1 0.0 0.17 11.8 0.0 2.4 1 0 0 1 1 1 0 F-box T2SSE PF00437.20 EGF81762.1 - 0.035 13.2 0.2 6.8 5.7 0.0 2.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EGF81762.1 - 0.053 14.0 0.5 14 6.2 0.0 3.9 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 EGF81762.1 - 0.062 13.7 2.2 1.6 9.2 0.0 4.6 7 0 0 7 7 4 0 RNA helicase AAA_19 PF13245.6 EGF81762.1 - 0.084 13.2 0.1 5 7.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EGF81762.1 - 0.22 11.3 4.4 9.5 6.1 0.1 3.7 4 0 0 4 4 4 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EGF81762.1 - 0.31 10.8 3.1 12 5.6 0.0 3.9 3 0 0 3 3 3 0 AAA domain PPR_2 PF13041.6 EGF81763.1 - 4.5e-25 87.6 9.7 6.3e-07 29.5 0.0 9.5 10 0 0 10 10 10 5 PPR repeat family PPR PF01535.20 EGF81763.1 - 1.2e-19 69.1 10.1 0.07 13.4 0.0 10.8 11 0 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 EGF81763.1 - 6e-17 61.5 1.2 1.1e-05 25.4 0.0 7.0 6 2 1 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF81763.1 - 9.4e-12 44.4 0.0 0.11 12.2 0.0 6.7 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 EGF81763.1 - 1.8e-07 30.8 6.1 0.12 11.7 0.0 5.6 5 1 0 5 5 5 3 Pentacotripeptide-repeat region of PRORP TAL_FSA PF00923.19 EGF81764.1 - 3.6e-100 335.0 0.3 4.1e-100 334.8 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PAP2 PF01569.21 EGF81765.1 - 4.6e-10 39.4 1.2 9.9e-10 38.3 0.6 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF2189 PF09955.9 EGF81765.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) DUF212 PF02681.14 EGF81765.1 - 0.037 14.2 0.0 0.64 10.1 0.0 2.2 1 1 1 2 2 2 0 Divergent PAP2 family SNase PF00565.17 EGF81766.1 - 2e-59 198.8 0.4 7.8e-21 74.6 0.0 5.7 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGF81766.1 - 6e-22 78.0 0.0 1.2e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 EGF81766.1 - 0.0062 17.0 0.3 0.024 15.1 0.0 2.1 2 0 0 2 2 2 1 Agenet domain Complex1_49kDa PF00346.19 EGF81768.1 - 1.1e-121 405.1 0.0 1.4e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EGF81768.1 - 0.002 17.1 0.0 0.0035 16.3 0.0 1.5 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RCC1_2 PF13540.6 EGF81770.1 - 4.4e-08 32.7 3.8 0.00056 19.6 0.5 5.8 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGF81770.1 - 0.0033 18.0 1.0 13 6.5 0.2 5.2 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Palm_thioest PF02089.15 EGF81771.1 - 3.1e-79 266.2 0.0 3.7e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGF81771.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TMEM70 PF06979.12 EGF81772.1 - 0.18 12.2 2.9 0.34 11.3 0.0 2.5 2 1 1 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex zf-H2C2_2 PF13465.6 EGF81773.1 - 1.3e-12 47.5 7.7 4.9e-06 26.7 0.2 2.5 2 1 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGF81773.1 - 4.1e-05 23.8 17.7 0.00025 21.3 2.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF81773.1 - 0.00014 22.4 1.2 0.00014 22.4 1.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf_UBZ PF18439.1 EGF81773.1 - 0.045 13.4 3.3 2.2 7.9 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HalOD2 PF18547.1 EGF81773.1 - 0.079 12.9 1.2 0.16 11.9 0.2 2.0 2 1 0 2 2 2 0 Halobacterial output domain 2 Zn_Tnp_IS1595 PF12760.7 EGF81773.1 - 0.26 11.3 7.8 4.9 7.2 3.3 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-AN1 PF01428.16 EGF81773.1 - 0.32 11.2 9.4 3.1 8.0 3.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 EGF81773.1 - 0.94 10.0 4.9 5.6 7.5 0.6 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 EGF81773.1 - 8.3 6.5 10.8 1.4 9.0 0.3 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger PPR_2 PF13041.6 EGF81774.1 - 7.1e-15 54.9 0.5 9.1e-08 32.2 0.1 4.6 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.20 EGF81774.1 - 2.6e-05 24.2 2.0 0.00016 21.7 0.2 3.3 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 EGF81774.1 - 0.0022 18.1 0.8 0.049 13.7 0.3 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EGF81774.1 - 0.06 12.7 0.6 5.9 6.2 0.6 2.9 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Choline_transpo PF04515.12 EGF81775.1 - 3.3e-59 200.7 18.9 3.3e-59 200.7 18.9 2.7 1 1 1 3 3 3 1 Plasma-membrane choline transporter Meckelin PF09773.9 EGF81775.1 - 0.15 10.1 8.2 0.0081 14.3 2.2 1.8 1 1 1 2 2 2 0 Meckelin (Transmembrane protein 67) AAA_5 PF07728.14 EGF81776.1 - 3.7e-121 399.5 0.1 2e-29 102.4 0.0 9.4 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGF81776.1 - 1.4e-54 182.8 6.0 5.6e-22 77.9 0.8 4.5 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_16 PF13191.6 EGF81776.1 - 8.3e-32 110.9 7.7 5.9e-07 30.0 0.2 7.6 7 0 0 7 7 7 6 AAA ATPase domain AAA_3 PF07726.11 EGF81776.1 - 5.2e-31 107.2 0.0 1e-09 38.4 0.0 7.7 7 1 1 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGF81776.1 - 2.5e-30 105.6 0.0 0.00016 22.1 0.0 6.9 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF81776.1 - 1.4e-28 99.6 3.6 1.9e-06 27.5 0.0 7.1 8 0 0 8 8 6 4 P-loop containing dynein motor region AAA_lid_5 PF17865.1 EGF81776.1 - 1.3e-27 95.9 0.1 1e-25 89.8 0.0 2.8 2 0 0 2 2 2 1 Midasin AAA lid domain Dynein_heavy PF03028.15 EGF81776.1 - 6.8e-24 84.3 0.0 0.00013 22.0 0.0 7.4 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 EGF81776.1 - 5.3e-22 78.2 0.0 0.0028 16.7 0.0 10.1 10 1 2 12 12 11 5 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 EGF81776.1 - 2e-21 76.9 0.1 0.011 16.2 0.1 6.8 6 0 0 6 6 6 5 AAA domain Sigma54_activat PF00158.26 EGF81776.1 - 4.4e-20 72.1 0.0 0.0069 16.1 0.1 6.7 6 1 0 6 6 6 3 Sigma-54 interaction domain AAA_22 PF13401.6 EGF81776.1 - 1.7e-19 70.5 0.1 0.0041 17.4 0.1 7.3 6 0 0 6 6 6 4 AAA domain ABC_tran PF00005.27 EGF81776.1 - 4.1e-18 66.2 0.5 0.00086 19.8 0.0 6.5 6 0 0 6 6 6 3 ABC transporter AAA_30 PF13604.6 EGF81776.1 - 2e-17 63.5 0.0 0.0013 18.5 0.0 7.9 7 2 0 7 7 7 4 AAA domain TsaE PF02367.17 EGF81776.1 - 1.9e-16 60.2 0.5 0.026 14.5 0.0 5.9 6 0 0 6 6 5 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EGF81776.1 - 3.9e-16 59.4 1.4 0.00018 21.6 0.0 6.5 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_14 PF13173.6 EGF81776.1 - 8.2e-16 58.2 0.0 0.2 11.7 0.0 7.4 7 0 0 7 7 7 3 AAA domain AAA_33 PF13671.6 EGF81776.1 - 2.7e-14 53.5 0.3 0.17 12.0 0.0 6.6 6 0 0 6 6 6 3 AAA domain Rad17 PF03215.15 EGF81776.1 - 3.5e-14 53.1 1.6 0.027 14.4 0.0 6.3 6 0 0 6 6 6 2 Rad17 P-loop domain AAA_28 PF13521.6 EGF81776.1 - 4.2e-14 53.1 2.9 0.57 10.4 0.1 6.8 7 0 0 7 7 6 3 AAA domain RNA_helicase PF00910.22 EGF81776.1 - 4.9e-14 52.6 0.1 0.19 12.2 0.0 6.5 6 0 0 6 6 6 2 RNA helicase NACHT PF05729.12 EGF81776.1 - 1.8e-12 47.5 2.2 0.12 12.3 0.1 5.8 6 0 0 6 6 5 4 NACHT domain T2SSE PF00437.20 EGF81776.1 - 3.2e-12 46.1 2.7 0.28 10.2 0.0 6.2 6 0 0 6 6 6 2 Type II/IV secretion system protein RuvB_N PF05496.12 EGF81776.1 - 1.2e-11 44.6 7.9 0.056 13.2 0.1 7.7 7 1 0 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGF81776.1 - 4.5e-11 43.3 4.6 0.095 13.0 0.1 7.4 8 1 0 8 8 5 1 AAA domain AAA_29 PF13555.6 EGF81776.1 - 4.9e-11 42.2 3.0 1.7 8.5 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGF81776.1 - 5.8e-11 42.3 1.3 0.17 11.5 0.1 6.0 6 0 0 6 6 6 2 AAA domain DUF815 PF05673.13 EGF81776.1 - 7.4e-11 41.7 3.7 0.094 11.9 0.0 5.8 6 0 0 6 6 6 3 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGF81776.1 - 9.6e-11 41.5 5.7 0.47 9.8 0.2 8.1 8 1 0 8 8 7 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EGF81776.1 - 2.2e-10 40.1 2.0 0.31 10.3 0.0 6.0 6 0 0 6 6 6 1 Zeta toxin RsgA_GTPase PF03193.16 EGF81776.1 - 3.1e-10 40.2 4.2 0.58 10.0 0.0 6.2 6 0 0 6 6 6 2 RsgA GTPase AAA_24 PF13479.6 EGF81776.1 - 9.7e-10 38.5 0.0 0.68 9.6 0.0 6.2 6 0 0 6 6 6 1 AAA domain AAA_23 PF13476.6 EGF81776.1 - 1.9e-09 38.4 2.2 1.6 9.2 0.0 6.0 6 1 0 6 6 5 1 AAA domain TniB PF05621.11 EGF81776.1 - 3.5e-09 36.3 0.8 1.9 7.9 0.0 6.9 6 1 1 7 7 7 1 Bacterial TniB protein AAA_8 PF12780.7 EGF81776.1 - 3.5e-08 33.1 0.1 0.095 12.0 0.0 4.8 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 EGF81776.1 - 1.1e-07 31.7 0.4 0.17 11.6 0.0 5.3 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGF81776.1 - 1.2e-07 31.5 1.2 1.5 8.3 0.0 5.2 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EGF81776.1 - 1.3e-07 31.9 0.9 4 7.7 0.1 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGF81776.1 - 1.3e-07 31.6 3.1 3.2 7.5 0.2 6.3 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EGF81776.1 - 1.4e-07 31.3 0.9 0.45 10.1 0.1 5.0 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EGF81776.1 - 1.8e-07 31.3 3.7 0.42 10.5 0.0 5.3 5 0 0 5 5 4 1 NTPase MMR_HSR1 PF01926.23 EGF81776.1 - 2.1e-07 31.0 0.2 40 4.3 0.0 6.5 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_11 PF13086.6 EGF81776.1 - 3e-07 30.5 0.9 14 5.4 0.0 6.2 6 0 0 6 6 6 0 AAA domain AAA_2 PF07724.14 EGF81776.1 - 6.3e-07 29.7 0.0 8.2 6.5 0.0 6.5 7 1 0 7 7 5 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGF81776.1 - 1.1e-06 28.6 2.7 3.7 7.3 0.0 7.1 8 0 0 8 8 7 0 IstB-like ATP binding protein dNK PF01712.19 EGF81776.1 - 1.1e-06 28.6 3.8 2.3 8.0 0.0 6.3 6 1 0 6 6 6 0 Deoxynucleoside kinase MCM PF00493.23 EGF81776.1 - 6.4e-06 25.4 0.0 0.12 11.4 0.0 4.5 4 0 0 4 4 4 1 MCM P-loop domain Viral_helicase1 PF01443.18 EGF81776.1 - 1.1e-05 25.3 0.1 0.66 9.7 0.0 4.8 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 EGF81776.1 - 3.2e-05 23.9 0.1 0.59 9.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGF81776.1 - 3.5e-05 23.7 0.0 0.27 10.9 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 EGF81776.1 - 4.3e-05 23.6 0.0 20 5.0 0.0 5.9 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea CPT PF07931.12 EGF81776.1 - 4.5e-05 23.4 0.3 6.8 6.5 0.0 6.4 7 0 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EGF81776.1 - 8.3e-05 22.6 0.0 3.7 7.5 0.0 4.9 6 0 0 6 6 4 0 Type III restriction enzyme, res subunit SRPRB PF09439.10 EGF81776.1 - 0.00016 21.2 0.9 12 5.3 0.1 5.4 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 EGF81776.1 - 0.00016 20.9 0.3 15 4.7 0.0 4.5 4 0 0 4 4 4 0 NB-ARC domain Cytidylate_kin PF02224.18 EGF81776.1 - 0.00029 20.7 0.3 6.4 6.5 0.0 4.4 4 0 0 4 4 4 0 Cytidylate kinase IPT PF01745.16 EGF81776.1 - 0.00029 20.3 0.8 3 7.2 0.0 4.1 5 0 0 5 5 3 0 Isopentenyl transferase TIP49 PF06068.13 EGF81776.1 - 0.00038 19.8 0.2 11 5.1 0.0 4.8 5 0 0 5 5 5 0 TIP49 P-loop domain ATP-synt_ab PF00006.25 EGF81776.1 - 0.0004 20.1 0.0 5.3 6.6 0.0 4.1 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 EGF81776.1 - 0.00042 19.7 0.3 6 6.1 0.0 4.6 5 0 0 5 5 4 0 KaiC DEAD PF00270.29 EGF81776.1 - 0.00056 19.7 0.0 4.9 6.9 0.0 4.2 4 0 0 4 4 3 0 DEAD/DEAH box helicase CbiA PF01656.23 EGF81776.1 - 0.00088 19.3 0.1 5.9 7.0 0.0 4.0 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DAP3 PF10236.9 EGF81776.1 - 0.0015 17.8 0.8 2.5 7.2 0.0 4.0 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 KAP_NTPase PF07693.14 EGF81776.1 - 0.004 16.4 0.0 16 4.6 0.0 4.3 5 0 0 5 5 5 0 KAP family P-loop domain MobB PF03205.14 EGF81776.1 - 0.0056 16.6 2.1 28 4.6 0.0 4.8 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 EGF81776.1 - 0.0091 15.3 0.4 15 4.7 0.1 4.2 5 0 0 5 5 4 0 Septin AAA_17 PF13207.6 EGF81776.1 - 0.012 16.1 3.6 12 6.4 0.0 4.4 5 0 0 5 5 4 0 AAA domain TrwB_AAD_bind PF10412.9 EGF81776.1 - 0.031 13.2 0.2 7.3 5.4 0.0 3.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain FeoB_N PF02421.18 EGF81776.1 - 0.053 13.0 2.0 35 3.9 0.0 4.3 5 0 0 5 5 4 0 Ferrous iron transport protein B G-alpha PF00503.20 EGF81776.1 - 0.069 12.3 1.4 17 4.4 0.0 3.6 5 0 0 5 5 3 0 G-protein alpha subunit Thymidylate_kin PF02223.17 EGF81776.1 - 0.072 12.8 0.7 1.9e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Thymidylate kinase tRNA_lig_kinase PF08303.11 EGF81776.1 - 0.081 13.0 0.1 1 9.4 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF2075 PF09848.9 EGF81776.1 - 0.1 11.8 1.8 4.9 6.3 0.0 3.8 5 0 0 5 5 3 0 Uncharacterized conserved protein (DUF2075) Ras PF00071.22 EGF81776.1 - 0.12 12.0 0.6 82 2.7 0.0 4.1 4 0 0 4 4 4 0 Ras family FtsK_SpoIIIE PF01580.18 EGF81776.1 - 0.16 11.3 5.0 10 5.4 0.0 3.8 5 0 0 5 5 3 0 FtsK/SpoIIIE family SKI PF01202.22 EGF81776.1 - 0.17 12.0 0.6 93 3.1 0.1 4.0 4 0 0 4 4 3 0 Shikimate kinase Dynamin_N PF00350.23 EGF81776.1 - 0.18 11.8 0.9 15 5.6 0.0 3.7 4 0 0 4 4 4 0 Dynamin family DLIC PF05783.11 EGF81776.1 - 0.29 9.9 0.5 64 2.2 0.1 3.3 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) UvrD-helicase PF00580.21 EGF81776.1 - 0.31 10.5 4.1 11 5.5 0.0 4.0 5 0 0 5 5 3 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 EGF81776.1 - 2.6 8.1 6.1 34 4.4 0.0 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain MutS_V PF00488.21 EGF81778.1 - 1e-77 260.5 0.0 2.5e-77 259.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EGF81778.1 - 2e-32 111.8 0.1 4.7e-32 110.6 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EGF81778.1 - 3.2e-29 102.5 0.0 1e-28 100.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EGF81778.1 - 1.1e-11 45.1 0.3 1.1e-09 38.7 0.1 3.1 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EGF81778.1 - 4.2e-09 36.6 0.3 1.1e-08 35.2 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV Metallophos PF00149.28 EGF81779.1 - 6.8e-33 114.9 0.5 9.9e-33 114.4 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGF81779.1 - 7.9e-27 93.4 0.2 1.3e-26 92.7 0.2 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_16 PF13432.6 EGF81779.1 - 0.0014 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81779.1 - 0.005 17.6 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF81779.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81779.1 - 0.03 14.8 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGF81779.1 - 0.04 13.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 EGF81779.1 - 0.1 12.4 0.0 0.5 10.3 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGF81779.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Complex1_51K PF01512.17 EGF81780.1 - 4.1e-48 163.1 0.0 5.8e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGF81780.1 - 1.4e-30 105.2 0.1 2.5e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGF81780.1 - 2.5e-08 33.6 0.0 5.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EGF81780.1 - 0.22 11.6 0.6 0.47 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Piwi PF02171.17 EGF81781.1 - 4.5e-102 341.3 0.0 6.9e-102 340.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGF81781.1 - 1.5e-23 83.9 0.0 3.3e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 EGF81781.1 - 1.6e-21 76.6 0.1 2.9e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EGF81781.1 - 3.1e-16 58.8 0.0 8.4e-16 57.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EGF81781.1 - 1e-12 48.2 0.0 2.4e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EGF81781.1 - 1.3e-11 44.6 0.0 4.6e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Mid domain of argonaute NFACT-R_1 PF05670.13 EGF81782.1 - 1.7e-41 141.3 0.0 2.6e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF1318 PF07027.12 EGF81782.1 - 0.022 15.2 0.6 0.039 14.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) DUF5624 PF18538.1 EGF81782.1 - 0.028 14.5 1.9 0.74 9.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) YcgL PF05166.13 EGF81782.1 - 0.099 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 YcgL domain Pinin_SDK_memA PF04696.13 EGF81782.1 - 8.7 6.4 11.6 5.5 7.0 9.1 1.8 1 1 1 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF3421 PF11901.8 EGF81783.1 - 1.9e-28 98.7 0.4 1.9e-16 60.1 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CPL PF08144.11 EGF81784.1 - 3.9e-26 92.1 3.6 1.1e-22 80.9 0.1 4.6 4 2 1 5 5 5 2 CPL (NUC119) domain PUF PF00806.19 EGF81784.1 - 5.4e-09 35.3 0.3 0.25 11.1 0.0 5.7 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF4020 PF13212.6 EGF81784.1 - 0.044 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) Methyltransf_23 PF13489.6 EGF81785.1 - 1e-21 77.5 0.0 3.4e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF81785.1 - 3.8e-21 75.5 0.0 7.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF81785.1 - 3.4e-16 59.7 0.1 6.2e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF81785.1 - 4e-14 52.7 0.0 5.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF81785.1 - 5.5e-14 52.7 0.0 9.8e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGF81785.1 - 2.4e-12 46.8 0.0 3.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGF81785.1 - 3.7e-07 29.8 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EGF81785.1 - 0.00034 20.0 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGF81785.1 - 0.0013 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGF81785.1 - 0.0036 16.3 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EGF81785.1 - 0.0041 16.7 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGF81785.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 EGF81785.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 EGF81785.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 EGF81785.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 EGF81785.1 - 0.19 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) bZIP_1 PF00170.21 EGF81786.1 - 2.2e-07 30.9 12.9 5.3e-07 29.6 12.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGF81786.1 - 1.4e-06 28.3 9.7 1.4e-06 28.3 9.7 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 EGF81786.1 - 0.00062 20.2 8.8 0.0015 19.0 8.8 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor UPF0242 PF06785.11 EGF81786.1 - 0.16 12.0 4.2 0.49 10.5 4.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RabGAP-TBC PF00566.18 EGF81787.1 - 4.7e-30 104.9 1.9 2.5e-29 102.5 1.9 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_16 PF10294.9 EGF81788.1 - 1.5e-17 63.8 2.4 2.7e-15 56.5 0.6 2.2 1 1 1 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 EGF81788.1 - 2.6e-07 30.3 0.2 4.4e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGF81788.1 - 2.8e-07 30.2 0.1 5.4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGF81788.1 - 1.5e-06 28.8 0.1 1.1e-05 26.0 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF81788.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGF81788.1 - 0.0002 21.1 0.1 0.00037 20.2 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 NNMT_PNMT_TEMT PF01234.17 EGF81788.1 - 0.0042 16.3 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family PCMT PF01135.19 EGF81788.1 - 0.014 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGF81788.1 - 0.039 13.8 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGF81788.1 - 0.042 14.5 0.0 0.11 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGF81788.1 - 0.13 13.0 0.0 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain cNMP_binding PF00027.29 EGF81789.1 - 1.1e-12 47.8 0.0 6e-09 35.9 0.0 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 EGF81790.1 - 3.6e-18 65.4 0.0 4.4e-12 45.9 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain CNP_C_terminal PF17839.1 EGF81790.1 - 0.13 13.0 0.2 0.41 11.4 0.2 1.9 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase Mad3_BUB1_I PF08311.12 EGF81791.1 - 6.6e-37 126.3 0.3 1.3e-36 125.3 0.3 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EGF81791.1 - 2.1e-06 27.3 0.0 1.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81791.1 - 0.06 12.6 0.2 0.21 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase ABC_tran PF00005.27 EGF81792.1 - 2.8e-19 70.0 0.0 1.9e-08 34.9 0.0 2.4 1 1 1 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGF81792.1 - 1.6e-10 41.3 0.3 2.7e-07 30.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGF81792.1 - 0.00027 20.4 0.0 0.054 12.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain cobW PF02492.19 EGF81792.1 - 0.0044 16.6 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EGF81792.1 - 0.0048 16.7 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA PF00004.29 EGF81792.1 - 0.0048 17.3 0.1 0.016 15.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGF81792.1 - 0.005 16.2 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGF81792.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGF81792.1 - 0.11 12.5 0.0 0.96 9.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGF81792.1 - 0.13 11.9 0.2 8.1 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGF81792.1 - 0.22 12.0 0.6 0.32 11.5 0.6 1.4 1 1 0 1 1 1 0 AAA domain Glyco_hydro_16 PF00722.21 EGF81793.1 - 1.7e-25 89.5 0.1 2.9e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Yip1 PF04893.17 EGF81794.1 - 7.3e-11 42.1 17.6 1.7e-10 40.9 17.8 1.5 1 1 0 1 1 1 1 Yip1 domain YrhC PF14143.6 EGF81794.1 - 0.12 12.4 2.7 0.33 11.1 2.7 1.7 1 0 0 1 1 1 0 YrhC-like protein MRAP PF15183.6 EGF81794.1 - 1 9.3 0.0 1 9.3 0.0 2.9 3 1 1 4 4 4 0 Melanocortin-2 receptor accessory protein family Asp PF00026.23 EGF81796.1 - 5.2e-16 59.0 0.1 6.9e-16 58.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF81796.1 - 0.00048 19.9 0.1 0.0028 17.4 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal FlaC_arch PF05377.11 EGF81797.1 - 0.0048 17.3 1.2 0.15 12.5 0.1 2.5 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) POP1 PF06978.11 EGF81797.1 - 0.038 14.0 1.3 0.051 13.6 1.3 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 ABC_tran_CTD PF16326.5 EGF81797.1 - 0.054 13.8 0.3 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain TRAF_BIRC3_bd PF16673.5 EGF81797.1 - 3.2 7.6 5.4 0.56 10.0 0.2 2.3 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Pep1_7 PF17232.2 EGF81797.1 - 3.9 8.0 11.3 0.35 11.3 1.2 3.2 3 0 0 3 3 3 0 Elicitor peptide 1-7 eIF-3c_N PF05470.12 EGF81797.1 - 8.9 4.5 11.4 2.1 6.6 1.0 2.2 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus COPIIcoated_ERV PF07970.12 EGF81798.1 - 2.8e-33 115.6 0.0 5.6e-33 114.6 0.0 1.5 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGF81798.1 - 3.2e-22 78.7 0.2 6.4e-22 77.7 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4828 PF16110.5 EGF81798.1 - 4.3e-05 23.9 0.4 9.6e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4828) NatB_MDM20 PF09797.9 EGF81799.1 - 8.7e-92 308.0 8.1 2.9e-91 306.3 8.1 1.9 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EGF81799.1 - 1.8e-08 34.8 1.2 0.0005 20.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF81799.1 - 0.0015 18.7 2.1 3.2 8.0 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGF81799.1 - 0.034 14.3 2.4 8.4 6.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat POR_N PF01855.19 EGF81799.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPR_1 PF00515.28 EGF81799.1 - 0.18 11.7 2.9 16 5.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Rpp20 PF12328.8 EGF81800.1 - 2.7e-09 37.1 1.8 1.1e-08 35.1 0.1 2.3 2 1 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EGF81800.1 - 0.0001 22.0 0.1 0.0001 22.0 0.1 1.9 2 0 0 2 2 2 1 Alba Ribosomal_S5 PF00333.20 EGF81801.1 - 1.5e-29 101.8 0.5 3e-29 100.8 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGF81801.1 - 7.5e-25 86.2 0.0 1.3e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EGF81801.1 - 0.18 12.4 10.9 0.39 11.3 10.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rad1 PF02144.16 EGF81803.1 - 5.3e-72 242.2 0.1 1.2e-71 241.0 0.0 1.6 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 NOB1_Zn_bind PF08772.11 EGF81804.1 - 5.1e-33 113.1 1.8 1.2e-32 111.9 1.8 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EGF81804.1 - 1.4e-26 92.8 0.1 3e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease DZR PF12773.7 EGF81804.1 - 0.011 15.7 0.4 0.02 14.9 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGF81804.1 - 0.018 15.8 0.2 0.041 14.6 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family E6 PF00518.17 EGF81804.1 - 0.019 15.4 0.2 0.043 14.3 0.2 1.6 1 0 0 1 1 1 0 Early Protein (E6) Ribosomal_L37ae PF01780.19 EGF81804.1 - 0.042 13.9 0.2 0.12 12.5 0.2 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family HypA PF01155.19 EGF81804.1 - 0.08 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EGF81804.1 - 0.2 11.8 1.0 0.47 10.6 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-NADH-PPase PF09297.11 EGF81804.1 - 0.34 10.6 2.0 3.8 7.3 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 EGF81804.1 - 0.44 10.3 3.8 0.98 9.2 3.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DEAD PF00270.29 EGF81805.1 - 1.1e-49 168.6 0.0 6e-49 166.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF81805.1 - 9.4e-30 103.2 0.1 2.6e-29 101.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF81805.1 - 7.6e-05 22.8 0.0 0.00026 21.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 EGF81805.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) MMgT PF10270.9 EGF81806.1 - 5e-16 58.9 0.0 5.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Transglut_core PF01841.19 EGF81807.1 - 4.7e-15 56.0 0.4 1.1e-14 54.8 0.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 EGF81807.1 - 2.6e-10 40.1 1.4 6.4e-10 38.9 0.8 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain PAW PF04721.17 EGF81807.1 - 0.025 14.3 0.5 0.039 13.7 0.5 1.3 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Penaeidin PF05927.11 EGF81807.1 - 0.03 15.0 1.2 0.53 11.1 0.3 2.3 1 1 1 2 2 2 0 Penaeidin DnaJ_CXXCXGXG PF00684.19 EGF81807.1 - 0.49 10.8 3.2 9.2 6.7 0.0 2.6 2 1 0 2 2 2 0 DnaJ central domain Lar_restr_allev PF14354.6 EGF81807.1 - 2 8.9 8.4 1.3e+02 3.0 8.5 2.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-CW PF07496.15 EGF81807.1 - 2 8.5 7.1 7.4 6.7 1.3 2.8 2 0 0 2 2 2 0 CW-type Zinc Finger UQ_con PF00179.26 EGF81808.1 - 3.5e-50 169.3 0.0 4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF383 PF04063.14 EGF81809.1 - 1.5e-60 204.1 0.1 6.2e-60 202.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGF81809.1 - 6.2e-17 61.2 0.9 1.9e-16 59.7 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Adaptin_N PF01602.20 EGF81811.1 - 1.4e-37 129.5 13.9 1.8e-37 129.1 13.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGF81811.1 - 3e-08 33.9 1.7 9.3e-08 32.3 1.7 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGF81811.1 - 4.5e-05 23.4 0.0 0.34 11.3 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EGF81811.1 - 0.00012 22.4 0.3 0.012 15.9 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats Cnd3 PF12719.7 EGF81811.1 - 0.00066 19.0 1.5 0.67 9.1 0.9 2.9 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EGF81811.1 - 0.0042 17.2 5.7 4.8 7.4 0.1 4.4 1 1 2 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGF81811.1 - 0.016 15.7 0.0 0.58 10.7 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat TAF6_C PF07571.13 EGF81811.1 - 0.034 14.5 0.9 0.41 11.0 0.1 3.2 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain FSH1 PF03959.13 EGF81812.1 - 1.3e-41 142.6 0.0 2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) HLH PF00010.26 EGF81814.1 - 1.8e-11 43.8 2.2 4.5e-11 42.5 2.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PGM1_C PF18105.1 EGF81814.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 PGM1 C-terminal domain FAM76 PF16046.5 EGF81814.1 - 5 6.4 20.1 0.089 12.1 3.1 2.4 2 1 0 2 2 2 0 FAM76 protein STIMATE PF12400.8 EGF81815.1 - 3.6e-36 124.5 6.8 6.4e-36 123.7 6.8 1.4 1 0 0 1 1 1 1 STIMATE family DUF2569 PF10754.9 EGF81815.1 - 0.013 15.9 2.2 2.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Carb_kinase PF01256.17 EGF81817.1 - 2.6e-53 181.0 0.0 3.3e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EGF81817.1 - 3.3e-06 26.7 0.0 3.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase SANT_DAMP1_like PF16282.5 EGF81818.1 - 6.4e-27 93.6 1.4 6.4e-27 93.6 1.4 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EGF81818.1 - 0.00013 21.9 0.8 0.00025 21.0 0.8 1.5 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 EGF81818.1 - 0.0033 17.7 0.0 0.015 15.5 0.0 2.0 1 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGF81818.1 - 0.0045 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain LAMTOR5 PF16672.5 EGF81819.1 - 1.5e-05 24.8 0.6 0.0001 22.1 0.6 1.9 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Pkinase PF00069.25 EGF81820.1 - 1.4e-52 178.7 0.0 3.1e-39 134.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81820.1 - 5.2e-22 78.4 0.0 1.2e-21 77.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81820.1 - 2.2e-06 27.2 0.0 5.5e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF81820.1 - 0.0028 17.0 0.3 0.0028 17.0 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF81820.1 - 0.0038 16.9 0.3 0.0094 15.6 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 EGF81820.1 - 0.021 13.8 0.3 0.033 13.2 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EGF81820.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF81820.1 - 0.38 9.6 4.6 0.24 10.3 0.2 2.6 3 0 0 3 3 3 0 Haspin like kinase domain TANGO2 PF05742.12 EGF81821.1 - 8.6e-64 216.0 0.0 1.7e-45 156.1 0.0 2.4 2 0 0 2 2 2 2 Transport and Golgi organisation 2 ArfGap PF01412.18 EGF81821.1 - 0.19 11.8 0.9 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf LRR_6 PF13516.6 EGF81821.1 - 2 8.7 17.3 1.2 9.4 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich repeat PEX11 PF05648.14 EGF81822.1 - 2.1e-21 76.5 0.2 3.1e-21 75.9 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GDP_Man_Dehyd PF16363.5 EGF81824.1 - 1.5e-58 198.8 0.0 1.8e-57 195.2 0.0 2.2 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGF81824.1 - 5.4e-56 189.7 0.0 7.7e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF81824.1 - 1.1e-18 67.3 0.0 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGF81824.1 - 1.2e-15 57.4 0.0 1.2e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGF81824.1 - 4.3e-12 45.7 0.0 6.9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGF81824.1 - 5.3e-10 38.9 0.0 1.3e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGF81824.1 - 2.4e-06 27.6 1.3 4.2e-05 23.5 1.3 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGF81824.1 - 0.0054 16.6 0.0 0.034 14.0 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EGF81824.1 - 0.018 14.5 0.8 0.035 13.6 0.1 1.9 2 1 0 2 2 2 0 short chain dehydrogenase Lactamase_B PF00753.27 EGF81825.1 - 4.7e-15 56.1 2.1 4e-09 36.8 1.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EGF81825.1 - 5e-10 39.2 0.0 9.6e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EGF81825.1 - 4.6e-08 32.8 0.0 6.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF81825.1 - 0.00054 19.9 0.5 0.0009 19.2 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HTH_5 PF01022.20 EGF81825.1 - 0.0065 16.3 0.1 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF3287 PF11690.8 EGF81826.1 - 2.6 7.8 7.1 0.25 11.1 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF745 PF05335.13 EGF81826.1 - 4.8 6.8 18.6 0.9 9.2 13.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF745) CRAL_TRIO PF00650.20 EGF81827.1 - 3.2e-34 117.9 0.1 5.3e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGF81827.1 - 4.5e-10 39.6 0.5 1.3e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGF81827.1 - 0.025 14.7 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Tom37 PF10568.9 EGF81828.1 - 1.5e-31 109.3 0.0 2.3e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EGF81828.1 - 4.3e-23 81.9 0.0 7.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGF81828.1 - 3e-20 71.8 0.1 5.5e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGF81828.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Imm65 PF15582.6 EGF81828.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 65 GST_C PF00043.25 EGF81828.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LAB_N PF07578.11 EGF81828.1 - 0.071 13.2 0.4 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain LRR_4 PF12799.7 EGF81830.1 - 1.3e-15 57.3 22.1 7.3e-09 35.8 5.6 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF81830.1 - 1.5e-11 43.9 16.4 1e-08 34.8 5.6 4.3 2 2 2 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 EGF81830.1 - 7.7e-05 22.3 6.0 0.00095 18.7 1.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat DUF1106 PF06523.11 EGF81830.1 - 0.084 12.9 0.5 0.35 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) LRR_6 PF13516.6 EGF81830.1 - 0.13 12.4 12.2 6 7.2 1.5 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EGF81830.1 - 0.4 11.4 11.5 11 7.0 0.4 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 EGF81831.1 - 1.8e-74 250.4 0.0 2.1e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81831.1 - 5.4e-45 153.7 0.0 6.3e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81831.1 - 3.4e-05 23.3 0.0 6.9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF81831.1 - 4.8e-05 23.0 0.3 6.8e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF81831.1 - 0.0027 17.1 0.2 0.0041 16.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF81831.1 - 0.012 14.5 0.1 0.017 14.1 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGF81831.1 - 0.017 15.1 0.1 0.25 11.3 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family MukB PF04310.12 EGF81831.1 - 0.12 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 MukB N-terminal KA1 PF02149.19 EGF81832.1 - 7.2e-17 60.9 0.0 1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 BK_channel_a PF03493.18 EGF81834.1 - 1e-24 86.6 0.2 7.8e-24 83.7 0.1 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGF81834.1 - 2.6e-11 43.3 4.8 2.6e-11 43.3 4.8 2.4 2 0 0 2 2 2 1 Ion channel MFS_1 PF07690.16 EGF81834.1 - 2.6 6.9 10.3 1.4 7.8 3.0 2.8 3 0 0 3 3 3 0 Major Facilitator Superfamily Y_phosphatase2 PF03162.13 EGF81835.1 - 1e-57 194.3 0.0 1.3e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGF81835.1 - 3.1e-07 30.6 0.0 4.5e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGF81835.1 - 0.002 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGF81835.1 - 0.0054 16.6 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain WD40 PF00400.32 EGF81836.1 - 5.7e-13 49.1 8.7 0.12 13.3 0.0 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF81836.1 - 6.6e-09 35.9 3.5 0.022 15.1 0.0 6.3 6 2 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF81836.1 - 1.5e-05 25.0 1.2 0.06 13.2 0.1 5.1 3 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Mcl1_mid PF12341.8 EGF81836.1 - 0.007 15.7 0.0 0.22 10.8 0.0 3.0 1 1 2 3 3 3 1 Minichromosome loss protein, Mcl1, middle region IKI3 PF04762.12 EGF81836.1 - 0.015 13.3 0.1 4.5 5.1 0.0 2.7 2 1 0 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.14 EGF81836.1 - 0.046 12.8 1.7 6.2 5.7 0.0 4.1 5 0 0 5 5 5 0 Coatomer WD associated region FliM PF02154.15 EGF81836.1 - 0.049 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar motor switch protein FliM FERM_F1 PF18379.1 EGF81836.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain DUF2236 PF09995.9 EGF81839.1 - 3.3e-12 47.1 0.0 4.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF764 PF05561.11 EGF81839.1 - 0.15 11.9 0.1 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF764) DUF2236 PF09995.9 EGF81840.1 - 0.0021 18.3 1.0 0.005 17.1 0.2 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2236 PF09995.9 EGF81841.1 - 0.0068 16.6 0.1 0.014 15.6 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF155 PF02582.14 EGF81842.1 - 1.7e-54 184.6 0.0 2.1e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF5336 PF17270.2 EGF81842.1 - 0.027 14.1 1.1 0.047 13.3 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Cation_efflux PF01545.21 EGF81844.1 - 1.4e-47 162.0 19.3 2.3e-47 161.3 19.3 1.3 1 1 0 1 1 1 1 Cation efflux family bMG1 PF17970.1 EGF81844.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain DUF2157 PF09925.9 EGF81844.1 - 9.1 6.1 7.7 1.4 8.7 2.1 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Lectin_leg-like PF03388.13 EGF81845.1 - 5.6e-36 124.0 0.2 1.5e-35 122.6 0.2 1.7 1 1 0 1 1 1 1 Legume-like lectin family Acid_PPase PF12689.7 EGF81845.1 - 0.038 13.8 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Acid Phosphatase Inhibitor_I9 PF05922.16 EGF81845.1 - 0.44 11.2 2.8 3.9 8.2 0.0 3.0 3 1 0 3 3 3 0 Peptidase inhibitor I9 CorA PF01544.18 EGF81845.1 - 2.5 7.4 5.6 11 5.2 5.3 2.2 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Ssu72 PF04722.13 EGF81846.1 - 4.8e-81 270.9 0.0 5.5e-81 270.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF4821 PF16092.5 EGF81847.1 - 3.9e-46 157.8 2.4 1.4e-40 139.6 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 EGF81847.1 - 0.00011 21.6 0.0 0.00026 20.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TOPRIM_C PF16898.5 EGF81847.1 - 0.36 11.1 4.7 0.72 10.1 0.5 2.6 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM PPR_3 PF13812.6 EGF81848.1 - 6.3e-10 39.0 4.4 7e-07 29.2 0.6 4.7 4 2 2 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF81848.1 - 4e-08 33.3 8.0 0.12 12.6 0.0 4.8 6 0 0 6 6 6 3 PPR repeat family PPR_1 PF12854.7 EGF81848.1 - 6.1e-08 32.2 0.1 0.04 13.6 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 EGF81848.1 - 1.6e-05 24.8 20.1 0.0028 17.8 0.0 6.5 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 EGF81848.1 - 0.00016 21.1 2.9 0.52 9.6 0.0 3.3 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EGF81848.1 - 0.016 16.0 0.2 8.7 7.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ECSIT PF06239.11 EGF81848.1 - 0.18 10.9 0.4 4.5 6.3 0.0 2.2 1 1 1 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway PAP2 PF01569.21 EGF81849.1 - 2.6e-24 85.5 5.7 2.6e-24 85.5 5.7 2.3 1 1 1 2 2 2 1 PAP2 superfamily Arc_PepC_II PF06847.11 EGF81849.1 - 0.063 13.8 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Asparaginase_2 PF01112.18 EGF81850.1 - 1.3e-29 103.3 3.5 2.1e-28 99.3 3.5 2.3 1 1 0 1 1 1 1 Asparaginase PX PF00787.24 EGF81851.1 - 7.9e-19 67.7 0.1 3.6e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 PX domain TPR_MLP1_2 PF07926.12 EGF81851.1 - 0.0012 18.9 1.1 0.3 11.1 0.7 2.5 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein WVELL PF14043.6 EGF81851.1 - 0.021 14.6 0.3 0.19 11.5 0.0 2.5 1 1 1 2 2 2 0 WVELL protein FAM92 PF06730.11 EGF81851.1 - 0.03 13.7 1.0 0.055 12.9 1.0 1.3 1 0 0 1 1 1 0 FAM92 protein Vps5 PF09325.10 EGF81851.1 - 0.038 13.5 9.8 0.071 12.7 0.3 2.4 3 0 0 3 3 3 0 Vps5 C terminal like DUF1258 PF06869.12 EGF81852.1 - 0.029 13.8 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) TP53IP5 PF15331.6 EGF81854.1 - 0.19 11.8 16.2 0.24 11.5 0.1 2.4 2 1 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Hist_deacetyl PF00850.19 EGF81855.1 - 3.6e-87 292.7 0.1 4.5e-87 292.4 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Phi_1 PF04674.12 EGF81856.1 - 4.4e-33 114.8 2.0 1.7e-32 112.8 2.0 1.8 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region Glyco_hydro_98C PF08307.11 EGF81856.1 - 0.00085 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain DICT PF10069.9 EGF81856.1 - 0.2 11.4 0.2 0.4 10.5 0.0 1.6 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system Phi_1 PF04674.12 EGF81857.1 - 3.2e-38 131.6 1.0 7e-38 130.5 1.0 1.6 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region Ice_nucleation PF00818.17 EGF81857.1 - 0.86 9.8 4.0 3.6 7.9 4.0 2.1 1 0 0 1 1 1 0 Ice nucleation protein repeat TFIIIC_sub6 PF10419.9 EGF81859.1 - 1.8e-16 59.8 0.0 2.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain IFT46_B_C PF12317.8 EGF81860.1 - 2.5e-13 50.3 6.1 3e-13 50.0 1.0 2.3 1 1 1 2 2 2 2 Intraflagellar transport complex B protein 46 C terminal 3Beta_HSD PF01073.19 EGF81861.1 - 6.4e-72 241.9 0.1 7.7e-72 241.6 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGF81861.1 - 8.1e-30 104.1 0.0 1.1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGF81861.1 - 1.3e-14 54.4 0.0 2.4e-14 53.5 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGF81861.1 - 2.9e-13 49.6 1.6 1.9e-09 37.1 0.1 2.4 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGF81861.1 - 1.5e-12 47.8 0.0 2.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGF81861.1 - 2.2e-09 36.8 0.0 3.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGF81861.1 - 5.7e-08 32.3 0.9 5.5e-07 29.0 0.8 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGF81861.1 - 0.00012 22.1 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 KR domain TrkA_N PF02254.18 EGF81861.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 EGF81861.1 - 0.0072 15.9 0.2 0.019 14.6 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EGF81861.1 - 0.035 13.6 1.4 0.27 10.7 1.4 2.2 1 1 0 1 1 1 0 short chain dehydrogenase LytR_cpsA_psr PF03816.14 EGF81861.1 - 0.035 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain Sacchrp_dh_NADP PF03435.18 EGF81861.1 - 0.064 13.5 1.2 0.41 10.9 1.2 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Auts2 PF15336.6 EGF81861.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein DUF5092 PF17010.5 EGF81862.1 - 3.7e-25 88.7 0.3 1.2e-17 64.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5092) zinc_ribbon_16 PF17034.5 EGF81863.1 - 1e-17 64.5 8.8 2e-17 63.6 8.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 EGF81863.1 - 0.0019 19.0 2.3 5 8.2 0.1 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.11 EGF81863.1 - 0.012 15.5 0.1 10 6.0 0.0 3.6 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PSI_integrin PF17205.3 EGF81863.1 - 2.7 7.8 8.5 24 4.8 4.9 3.4 3 0 0 3 3 3 0 Integrin plexin domain Thg1 PF04446.12 EGF81864.1 - 6.3e-50 168.4 0.2 9.6e-50 167.8 0.2 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGF81864.1 - 2e-39 134.5 0.1 5e-39 133.2 0.1 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain Regnase_1_C PF18561.1 EGF81864.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain Tim29 PF10171.9 EGF81865.1 - 0.032 13.7 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 DEC-1_N PF04625.13 EGF81865.1 - 0.19 10.7 1.8 0.24 10.3 1.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region APG6_N PF17675.1 EGF81865.1 - 0.35 11.4 12.8 0.19 12.3 9.6 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 EGF81865.1 - 0.47 10.3 8.7 2 8.2 0.6 2.7 1 1 2 3 3 3 0 Septum formation initiator ZapB PF06005.12 EGF81865.1 - 4.1 7.9 12.4 0.24 11.9 3.5 2.5 1 1 2 3 3 3 0 Cell division protein ZapB RRM_1 PF00076.22 EGF81866.1 - 1.6e-20 72.7 0.0 2.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF81866.1 - 0.0057 16.2 0.0 0.008 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF81866.1 - 0.051 13.7 0.0 0.078 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Peptidase_M20 PF01546.28 EGF81867.1 - 4.3e-33 114.8 0.0 6.2e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGF81867.1 - 6.4e-13 48.6 0.0 1.4e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain RNA_pol_Rbc25 PF08292.12 EGF81868.1 - 8.7e-36 123.0 0.0 1.1e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGF81868.1 - 3.1e-11 43.5 0.2 1.2e-09 38.4 0.1 2.6 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGF81868.1 - 0.13 12.6 0.0 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 S1 RNA binding domain Peptidase_S41 PF03572.18 EGF81869.1 - 4.5e-14 52.4 0.0 8.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_4 PF17816.1 EGF81869.1 - 0.055 13.9 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 PDZ domain DUF676 PF05057.14 EGF81870.1 - 7.3e-38 130.3 0.4 3.1e-36 124.9 0.4 2.2 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGF81870.1 - 5.2e-05 23.2 0.0 9.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGF81870.1 - 0.0039 16.9 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Oleosin PF01277.17 EGF81870.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Oleosin Lipase_3 PF01764.25 EGF81870.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF423 PF04241.15 EGF81871.1 - 3.4e-27 94.5 0.0 4.7e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Peptidase_M3 PF01432.20 EGF81872.1 - 3.5e-119 399.1 0.3 5.5e-118 395.1 0.3 2.1 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EGF81872.1 - 0.0031 17.9 0.1 0.0068 16.7 0.1 1.5 1 0 0 1 1 1 1 Effector protein Peptidase_M50B PF13398.6 EGF81872.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M32 PF02074.15 EGF81872.1 - 0.24 10.1 1.6 0.71 8.6 0.1 2.3 3 0 0 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase WD40 PF00400.32 EGF81874.1 - 9.3e-05 23.1 6.2 2.1 9.4 1.7 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat MYCBPAP PF14646.6 EGF81875.1 - 1.5e-52 179.0 1.5 5.4e-52 177.2 1.5 2.0 1 1 0 1 1 1 1 MYCBP-associated protein family Ycf66_N PF07444.11 EGF81875.1 - 0.0025 17.9 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 Ycf66 protein N-terminus TMEM131_like PF12371.8 EGF81875.1 - 0.97 9.7 2.8 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 131-like Fe-S_biosyn PF01521.20 EGF81877.1 - 4.9e-17 62.1 0.1 5.4e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SOR_SNZ PF01680.17 EGF81878.1 - 1.3e-111 371.3 3.6 2e-111 370.7 3.6 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGF81878.1 - 2.1e-08 33.8 6.9 4e-07 29.6 0.2 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGF81878.1 - 0.00013 21.1 0.3 0.34 9.9 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EGF81878.1 - 0.0002 21.4 0.0 0.0008 19.4 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 EGF81878.1 - 0.0024 17.1 0.3 0.061 12.5 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EGF81878.1 - 0.0057 16.1 0.8 0.33 10.4 0.1 2.8 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 EGF81878.1 - 0.015 14.5 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase OMPdecase PF00215.24 EGF81878.1 - 0.061 12.9 0.2 0.4 10.2 0.2 2.1 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TrkA_N PF02254.18 EGF81878.1 - 2.4 8.4 5.2 13 6.1 0.0 3.5 6 0 0 6 6 6 0 TrkA-N domain PX PF00787.24 EGF81879.1 - 8.7e-08 32.1 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 EGF81879.1 - 0.055 13.4 0.6 0.4 10.6 0.6 2.4 1 1 0 1 1 1 0 PB1 domain ABC_membrane PF00664.23 EGF81880.1 - 4.1e-55 187.4 13.2 5.8e-55 186.9 13.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGF81880.1 - 1.5e-31 109.8 0.0 3.7e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGF81880.1 - 8.2e-07 28.7 0.2 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF81880.1 - 3.8e-05 24.1 0.1 0.00011 22.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGF81880.1 - 0.00022 20.9 0.4 0.00053 19.7 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGF81880.1 - 0.003 17.8 0.3 0.052 13.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGF81880.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EGF81880.1 - 0.036 14.6 0.0 0.11 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF81880.1 - 0.037 13.6 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 EGF81880.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 EGF81880.1 - 0.044 13.5 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EGF81880.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EGF81880.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EGF81880.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EGF81880.1 - 0.072 13.2 0.0 0.46 10.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 EGF81880.1 - 0.089 12.9 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_33 PF13671.6 EGF81880.1 - 0.13 12.4 1.1 0.84 9.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 EGF81880.1 - 0.13 12.7 0.6 0.28 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain TrkA_N PF02254.18 EGF81880.1 - 0.51 10.6 2.6 2 8.7 0.1 3.2 3 1 0 3 3 3 0 TrkA-N domain Yip1 PF04893.17 EGF81880.1 - 5.3 6.7 15.6 0.74 9.5 5.7 2.4 2 1 0 2 2 2 0 Yip1 domain Ank_2 PF12796.7 EGF81881.1 - 1.3e-08 35.3 0.0 1.8e-08 34.8 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGF81881.1 - 2.4e-08 34.1 0.0 1.3e-06 28.6 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGF81881.1 - 6e-08 32.8 0.0 4.6e-06 26.8 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF81881.1 - 1.5e-06 28.1 0.0 0.0012 19.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EGF81881.1 - 1.7e-05 25.3 0.2 0.00022 21.7 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) E1-E2_ATPase PF00122.20 EGF81882.1 - 3e-43 147.4 1.3 1.3e-42 145.3 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGF81882.1 - 2.8e-22 80.1 2.2 2.2e-13 51.0 0.5 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGF81882.1 - 1.7e-19 70.2 19.9 3.2e-16 59.6 5.0 3.9 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGF81882.1 - 3.9e-16 58.9 0.0 7.5e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGF81882.1 - 1.6e-11 43.7 0.0 3.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF81882.1 - 0.0052 16.6 7.0 0.092 12.5 0.4 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGF81882.1 - 0.13 12.4 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2516 PF10724.9 EGF81882.1 - 0.25 11.7 3.8 0.2 11.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) CAP PF00188.26 EGF81883.1 - 6.2e-11 43.2 0.7 4.8e-10 40.4 0.7 2.1 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EGF81884.1 - 1.4e-20 74.4 0.8 2.7e-20 73.5 0.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EGF81885.1 - 4.5e-25 88.9 3.2 6.8e-25 88.3 3.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EGF81886.1 - 1.4e-17 64.7 0.0 2.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.11 EGF81886.1 - 0.0016 18.4 9.5 0.0023 17.9 9.5 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CAP PF00188.26 EGF81887.1 - 3.2e-19 70.0 0.3 5.9e-19 69.2 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4106 PF13388.6 EGF81887.1 - 0.96 8.6 4.5 1.2 8.3 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CAP PF00188.26 EGF81888.1 - 3.8e-14 53.6 0.5 6e-14 53.0 0.5 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HC2 PF07382.11 EGF81888.1 - 0.0013 18.9 36.8 0.002 18.3 36.8 1.3 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 UL40 PF10682.9 EGF81888.1 - 0.08 12.6 0.4 1.6 8.4 0.1 2.1 1 1 1 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 Ndc1_Nup PF09531.10 EGF81888.1 - 4.6 5.8 17.2 5.5 5.5 17.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF726 PF05277.12 EGF81889.1 - 2.8e-87 292.9 5.3 4e-87 292.4 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Aldose_epim PF01263.20 EGF81890.1 - 2.6e-53 181.3 0.0 4.2e-53 180.6 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase DUF402 PF04167.13 EGF81890.1 - 0.1 12.8 0.2 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF402) AATF-Che1 PF13339.6 EGF81891.1 - 5.2e-33 114.7 0.6 5.2e-33 114.7 0.6 3.2 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 EGF81891.1 - 1.9e-30 105.2 0.5 1.9e-30 105.2 0.5 2.7 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Mito_carr PF00153.27 EGF81892.1 - 8e-50 166.7 10.6 9.7e-18 63.9 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Proteasome PF00227.26 EGF81894.1 - 7.5e-61 204.9 0.0 8.9e-61 204.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF81894.1 - 4.8e-14 51.7 0.1 8.8e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF155 PF02582.14 EGF81895.1 - 1.6e-42 145.5 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PRKCSH_1 PF13015.6 EGF81895.1 - 0.12 12.1 0.1 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein IDO PF01231.18 EGF81897.1 - 1e-42 146.5 0.0 1.3e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF294_C PF10335.9 EGF81897.1 - 0.24 11.2 1.1 7.3 6.4 0.3 2.4 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Ank_2 PF12796.7 EGF81898.1 - 4.7e-06 27.1 0.1 7.1e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF81898.1 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGF81898.1 - 0.00076 20.0 0.1 0.0022 18.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGF81898.1 - 0.001 19.4 0.0 0.0029 18.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EGF81898.1 - 0.029 14.9 0.1 0.16 12.7 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Cons_hypoth698 PF03601.14 EGF81900.1 - 0.047 12.6 0.1 0.081 11.8 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 zf-RING_5 PF14634.6 EGF81901.1 - 1.5e-06 28.1 8.3 2.5e-06 27.3 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGF81901.1 - 1.6e-05 24.6 5.8 3e-05 23.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF81901.1 - 0.00042 20.1 5.9 0.00079 19.2 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGF81901.1 - 0.00098 19.4 4.5 0.0018 18.6 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 EGF81901.1 - 0.0015 18.4 3.2 0.0015 18.4 3.2 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Filament PF00038.21 EGF81901.1 - 0.0021 17.7 3.3 0.003 17.2 3.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein Syntaxin_2 PF14523.6 EGF81901.1 - 0.0022 18.3 8.5 0.0053 17.1 8.5 1.6 1 0 0 1 1 1 1 Syntaxin-like protein zf-RING_UBOX PF13445.6 EGF81901.1 - 0.0037 17.3 2.3 0.0056 16.7 1.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF81901.1 - 0.0038 17.0 7.3 0.0063 16.4 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF81901.1 - 0.0078 16.1 8.2 0.014 15.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 EGF81901.1 - 0.0095 15.3 0.5 0.018 14.4 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-rbx1 PF12678.7 EGF81901.1 - 0.02 15.2 4.1 0.02 15.2 4.1 1.7 2 0 0 2 2 1 0 RING-H2 zinc finger domain Phage_Mu_Gam PF07352.12 EGF81901.1 - 0.027 14.4 5.0 0.043 13.7 5.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1272 PF06906.11 EGF81901.1 - 0.033 14.3 4.6 0.071 13.2 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EGF81901.1 - 0.041 13.7 0.7 0.082 12.7 0.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YtxH PF12732.7 EGF81901.1 - 0.047 14.2 1.9 0.18 12.3 1.9 2.0 1 1 0 1 1 1 0 YtxH-like protein Caudo_TAP PF02413.17 EGF81901.1 - 0.05 13.7 2.3 0.087 13.0 2.0 1.5 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK FapA PF03961.13 EGF81901.1 - 0.093 11.3 1.8 0.13 10.9 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med30 PF11315.8 EGF81901.1 - 0.11 12.7 4.0 0.16 12.2 2.6 1.8 1 1 1 2 2 2 0 Mediator complex subunit 30 Prok-RING_1 PF14446.6 EGF81901.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF573 PF04504.14 EGF81901.1 - 0.17 12.5 2.1 0.4 11.4 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF573 V_ATPase_I PF01496.19 EGF81901.1 - 0.18 9.7 2.2 0.24 9.3 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 EGF81901.1 - 0.24 11.7 12.7 0.5 10.7 12.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) C1_4 PF07975.12 EGF81901.1 - 0.39 11.0 4.7 0.98 9.7 4.7 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-P11 PF03854.14 EGF81901.1 - 0.61 9.8 4.8 1.2 8.9 4.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 EGF81901.1 - 0.7 10.0 6.3 1.7 8.8 6.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon HemX PF04375.14 EGF81901.1 - 0.78 9.0 11.8 0.029 13.7 6.0 1.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4407 PF14362.6 EGF81901.1 - 0.84 8.9 5.7 1.3 8.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAT PF03127.14 EGF81901.1 - 0.94 9.8 5.6 5 7.5 1.8 2.3 1 1 1 2 2 2 0 GAT domain YlqD PF11068.8 EGF81901.1 - 1.4 9.3 11.5 2.8 8.3 11.5 1.5 1 0 0 1 1 1 0 YlqD protein ADK_lid PF05191.14 EGF81901.1 - 1.5 8.9 5.2 0.62 10.1 1.6 2.3 2 1 0 2 2 1 0 Adenylate kinase, active site lid FUSC PF04632.12 EGF81901.1 - 1.7 7.1 3.2 2.3 6.6 3.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MCU PF04678.13 EGF81901.1 - 4.1 7.5 6.0 31 4.6 6.1 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter DnaJ_C PF01556.18 EGF81902.1 - 9.2e-35 119.9 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGF81902.1 - 1.7e-25 88.9 2.6 2.7e-25 88.2 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGF81902.1 - 1.3e-10 41.5 16.6 2.4e-10 40.6 16.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGF81902.1 - 0.075 13.0 15.3 0.045 13.7 2.6 3.3 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF493 PF04359.14 EGF81902.1 - 0.1 13.2 0.2 0.28 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF493) DUF1769 PF08588.10 EGF81903.1 - 3.7e-20 71.9 0.1 7.7e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) PFK PF00365.20 EGF81904.1 - 2.5e-180 598.0 0.8 3.8e-95 318.5 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAHP_synth_1 PF00793.20 EGF81905.1 - 2e-91 305.7 0.0 2.6e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DEAD PF00270.29 EGF81907.1 - 5.8e-40 136.9 0.3 5.7e-39 133.7 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF81907.1 - 1.9e-27 95.8 0.6 1e-26 93.4 0.1 2.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF81907.1 - 2.1e-05 24.6 0.0 5.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGF81907.1 - 0.15 12.4 1.0 1.4 9.2 0.6 2.7 2 1 0 2 2 2 0 AAA domain GCFC PF07842.12 EGF81908.1 - 9.2e-09 35.3 0.2 7e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein Cna_B PF05738.13 EGF81908.1 - 0.042 14.4 0.3 0.12 12.9 0.3 1.8 1 0 0 1 1 1 0 Cna protein B-type domain Anillin_N PF16018.5 EGF81908.1 - 0.067 13.8 1.5 0.24 12.1 1.5 1.9 1 0 0 1 1 1 0 Anillin N-terminus DUF932 PF06067.11 EGF81908.1 - 0.3 10.8 3.2 0.16 11.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Pkinase PF00069.25 EGF81909.1 - 8.6e-72 241.7 0.0 9.7e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81909.1 - 1.1e-44 152.7 0.0 1.3e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF81909.1 - 5.2e-07 29.3 0.0 5.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF81909.1 - 1.7e-06 27.1 0.0 2.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF81909.1 - 0.025 13.9 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_1 PF00515.28 EGF81910.1 - 2.3e-68 223.4 27.9 0.00015 21.4 0.7 24.8 24 2 1 25 25 25 14 Tetratricopeptide repeat TPR_11 PF13414.6 EGF81910.1 - 6.2e-55 182.6 27.8 4.4e-05 23.1 0.1 20.2 13 5 10 23 23 23 12 TPR repeat TPR_2 PF07719.17 EGF81910.1 - 3.4e-54 176.7 25.1 0.00031 20.6 0.4 23.5 24 1 1 25 25 24 12 Tetratricopeptide repeat TPR_9 PF13371.6 EGF81910.1 - 9.8e-35 118.5 6.4 0.00022 21.3 0.0 12.5 7 4 6 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81910.1 - 2.3e-32 108.4 14.6 0.11 12.8 0.0 17.3 18 1 1 19 19 19 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGF81910.1 - 3.1e-31 105.5 37.8 0.024 15.0 0.0 20.6 23 0 0 23 23 21 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGF81910.1 - 1e-29 102.8 13.8 2.7e-05 24.7 0.3 11.8 10 2 3 13 13 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGF81910.1 - 2.7e-18 66.2 25.7 0.0029 18.1 1.0 12.1 9 4 4 13 13 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81910.1 - 2.6e-17 62.9 16.9 0.34 11.2 0.0 11.6 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81910.1 - 7.4e-16 57.5 15.1 2.6 9.1 0.0 14.0 10 5 7 17 17 16 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGF81910.1 - 2.5e-06 27.7 33.9 13 6.6 0.0 14.9 19 0 0 19 19 15 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF81910.1 - 4.9e-06 26.2 7.9 4 7.7 0.0 9.7 9 2 1 10 10 10 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGF81910.1 - 0.00061 19.5 7.3 0.17 11.6 0.0 5.4 5 1 1 6 6 6 1 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 EGF81910.1 - 0.0025 16.6 1.1 0.48 9.1 0.0 3.9 4 0 0 4 4 4 1 Protein kinase G tetratricopeptide repeat TPR_15 PF13429.6 EGF81910.1 - 0.091 12.0 9.3 2.5 7.2 0.1 6.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGF81910.1 - 0.11 12.9 11.5 3 8.2 0.1 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 EGF81910.1 - 0.18 12.2 0.7 53 4.2 0.0 3.7 4 1 0 4 4 3 0 Bacterial transcriptional activator domain DUF5113 PF17140.4 EGF81910.1 - 4.2 7.2 8.0 25 4.6 0.0 4.9 5 0 0 5 5 5 0 Domain of unknown function (DUF5113) Mcp5_PH PF12814.7 EGF81911.1 - 2.6e-18 66.3 2.2 8.8e-18 64.6 0.2 2.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_12 PF16457.5 EGF81911.1 - 0.005 17.4 11.3 0.074 13.6 0.1 4.5 4 0 0 4 4 4 2 Pleckstrin homology domain CCDC92 PF14916.6 EGF81911.1 - 2.1 8.2 13.5 0.36 10.6 0.5 4.6 3 1 1 4 4 4 0 Coiled-coil domain of unknown function zf-Tim10_DDP PF02953.15 EGF81912.1 - 3.4e-16 58.7 6.9 4.3e-16 58.3 6.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Dsl1_C PF11989.8 EGF81912.1 - 0.017 14.9 0.1 0.02 14.6 0.1 1.0 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal GFRP PF06399.13 EGF81912.1 - 0.18 11.7 0.0 0.23 11.3 0.0 1.3 1 1 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) AAA_2 PF07724.14 EGF81913.1 - 2.9e-43 148.0 0.0 4.9e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGF81913.1 - 8.5e-14 52.1 0.0 1.6e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGF81913.1 - 1.1e-10 41.4 0.2 2e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 EGF81913.1 - 1.5e-06 27.7 0.0 0.002 17.5 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGF81913.1 - 2.4e-05 24.4 0.0 5.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGF81913.1 - 0.00062 19.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 EGF81913.1 - 0.0014 17.8 0.0 0.0039 16.3 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 EGF81913.1 - 0.0014 18.4 0.7 0.036 13.8 0.2 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF81913.1 - 0.0062 16.8 0.6 0.089 13.1 0.1 2.5 2 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EGF81913.1 - 0.0096 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 EGF81913.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EGF81913.1 - 0.026 14.6 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGF81913.1 - 0.033 14.6 0.2 0.11 12.8 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EGF81913.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EGF81913.1 - 0.071 12.9 0.1 0.22 11.3 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 EGF81913.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein G-alpha PF00503.20 EGF81913.1 - 0.098 11.8 0.0 0.75 8.9 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 EGF81913.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EGF81913.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 EGF81913.1 - 0.14 11.4 0.2 0.41 9.8 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain CRAL_TRIO PF00650.20 EGF81914.1 - 5.9e-34 117.1 0.0 1e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGF81914.1 - 3.6e-07 30.3 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Helicase_C PF00271.31 EGF81914.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.7 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Shugoshin_C PF07557.11 EGF81915.1 - 6.8e-07 29.0 1.7 1.4e-06 28.0 1.7 1.6 1 0 0 1 1 1 1 Shugoshin C terminus tRNA-synt_1c PF00749.21 EGF81916.1 - 1.8e-108 362.1 0.0 2.8e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EGF81916.1 - 2.4e-48 164.2 0.2 4.1e-48 163.5 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EGF81916.1 - 7.1e-37 126.9 0.0 2.1e-36 125.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EGF81916.1 - 2.9e-15 57.0 0.6 6.6e-15 55.8 0.6 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Vps55 PF04133.14 EGF81918.1 - 5.9e-39 132.7 8.0 6.6e-39 132.5 8.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Suv3_C_1 PF18147.1 EGF81919.1 - 5.5e-16 58.2 0.2 9.6e-16 57.4 0.2 1.4 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EGF81919.1 - 3.5e-12 46.7 0.0 7.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EGF81919.1 - 0.049 13.6 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal MIP-T3 PF10243.9 EGF81920.1 - 0.00058 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain Dcc1 PF09724.9 EGF81921.1 - 6.4e-85 285.4 0.2 7.5e-85 285.2 0.2 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Carbam_trans_C PF16861.5 EGF81921.1 - 0.21 11.2 0.2 0.36 10.4 0.2 1.3 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus RSN1_7TM PF02714.15 EGF81922.1 - 3.3e-58 197.2 25.3 3.3e-58 197.2 25.3 2.1 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGF81922.1 - 4.3e-32 111.0 7.7 4.3e-32 111.0 7.7 2.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGF81922.1 - 2.6e-15 57.1 0.6 3.4e-07 30.7 0.0 2.5 1 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Thiolase_N PF00108.23 EGF81923.1 - 7.7e-90 300.8 4.0 1e-89 300.4 4.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF81923.1 - 3.3e-42 143.0 4.1 2.2e-41 140.4 0.5 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGF81923.1 - 5.5e-07 29.4 1.5 0.0002 21.0 0.2 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Tetraspanin PF00335.20 EGF81924.1 - 1.3e-11 44.6 7.0 1.8e-11 44.2 7.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 EGF81924.1 - 0.011 15.9 3.7 0.011 15.9 3.7 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF4064) zf-NF-X1 PF01422.17 EGF81925.1 - 0.0016 18.5 10.5 0.0016 18.5 10.5 13.2 12 1 0 12 12 12 5 NF-X1 type zinc finger Pkinase PF00069.25 EGF81926.1 - 4.7e-69 232.7 0.0 5.4e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF81926.1 - 5.6e-32 111.0 0.0 1.8e-31 109.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF81926.1 - 1.3e-05 24.4 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF81926.1 - 2.3e-05 23.8 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF81926.1 - 5.1e-05 22.7 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGF81926.1 - 0.18 10.8 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin PF08613.11 EGF81927.1 - 2.7e-33 115.6 1.1 4.6e-33 114.9 1.1 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGF81927.1 - 2.8e-05 23.9 1.7 4.8e-05 23.1 1.0 1.6 1 1 1 2 2 2 1 Cyclin, N-terminal domain Mlh1_C PF16413.5 EGF81928.1 - 5.1e-75 252.3 0.1 8.5e-75 251.6 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGF81928.1 - 8.7e-31 106.1 0.1 1.8e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGF81928.1 - 5.9e-12 45.6 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGF81928.1 - 3.6e-06 27.4 0.0 8.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 EGF81929.1 - 2.6e-18 66.7 0.1 1.7e-07 31.7 0.0 3.9 2 2 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF81929.1 - 1.8e-08 34.0 0.1 4.6e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGF81929.1 - 1.2e-06 29.0 0.5 0.037 14.4 0.0 2.8 1 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGF81929.1 - 6.2e-06 26.2 0.2 0.04 13.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 EGF81929.1 - 8.4e-06 26.4 0.0 0.0023 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGF81929.1 - 7.9e-05 22.9 0.0 0.48 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGF81929.1 - 9.5e-05 21.8 0.0 0.11 11.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EGF81929.1 - 0.00015 22.1 0.2 0.13 12.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EGF81929.1 - 0.00028 20.6 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 EGF81929.1 - 0.0011 19.0 0.0 0.95 9.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGF81929.1 - 0.0013 19.1 0.1 0.11 12.9 0.0 3.0 3 0 0 3 3 3 1 RNA helicase ATPase_2 PF01637.18 EGF81929.1 - 0.0014 18.6 0.0 0.074 13.0 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EGF81929.1 - 0.0042 16.8 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EGF81929.1 - 0.0095 15.5 0.0 7.5 6.0 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region RuvB_N PF05496.12 EGF81929.1 - 0.024 14.4 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EGF81929.1 - 0.025 14.5 0.0 14 5.6 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_5 PF07728.14 EGF81929.1 - 0.027 14.4 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGF81929.1 - 0.028 14.2 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGF81929.1 - 0.031 14.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGF81929.1 - 0.039 13.3 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 EGF81929.1 - 0.061 12.3 0.0 0.81 8.6 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF815 PF05673.13 EGF81929.1 - 0.069 12.3 0.0 5.9 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IPT PF01745.16 EGF81929.1 - 0.069 12.5 0.1 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Isopentenyl transferase Viral_helicase1 PF01443.18 EGF81929.1 - 0.098 12.4 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EGF81929.1 - 0.099 12.9 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGF81929.1 - 0.14 11.7 0.1 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGF81929.1 - 0.15 11.4 0.2 3.9 6.7 0.1 2.6 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.6 EGF81929.1 - 0.15 12.4 0.0 23 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF892 PF05974.12 EGF81929.1 - 0.18 11.8 0.1 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Aminotran_1_2 PF00155.21 EGF81930.1 - 1.1e-81 274.9 0.0 1.2e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acetyltransf_1 PF00583.25 EGF81931.1 - 7.8e-08 32.6 0.0 1.7e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Hat1_N PF10394.9 EGF81931.1 - 6.5e-05 23.2 0.5 0.00012 22.4 0.5 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 EGF81931.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF81931.1 - 0.0022 18.4 0.0 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EGF81931.1 - 0.015 14.9 0.5 0.026 14.2 0.5 1.3 1 0 0 1 1 1 0 MOZ/SAS family DEAD PF00270.29 EGF81932.1 - 1.4e-45 155.2 0.0 3.4e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF81932.1 - 2.3e-23 82.6 0.1 3.3e-22 78.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGF81932.1 - 1.1e-16 60.7 0.0 3.1e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGF81932.1 - 1.8e-05 24.8 5.8 2.4e-05 24.4 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGF81932.1 - 0.029 14.5 0.0 0.091 12.9 0.0 1.9 1 0 0 1 1 1 0 Helicase C-terminal domain INSIG PF07281.12 EGF81933.1 - 7e-35 120.6 13.1 2.8e-34 118.6 13.1 2.0 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) PseudoU_synth_1 PF01416.20 EGF81934.1 - 2.7e-12 47.1 0.0 1.1e-10 42.0 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase Nup84_Nup100 PF04121.13 EGF81935.1 - 8.4e-175 582.9 0.0 1.1e-174 582.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 KCH PF16944.5 EGF81936.1 - 6.4e-20 72.0 3.3 8.1e-20 71.7 3.3 1.1 1 0 0 1 1 1 1 Fungal potassium channel Hamartin PF04388.12 EGF81936.1 - 0.052 12.2 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Hamartin protein DUF2070 PF09843.9 EGF81936.1 - 7.5 4.7 10.5 0.26 9.5 3.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Oxysterol_BP PF01237.18 EGF81937.1 - 9.6e-127 422.9 2.4 3.9e-126 420.9 2.4 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein D123 PF07065.14 EGF81938.1 - 1.1e-104 349.9 0.2 1.3e-104 349.7 0.2 1.1 1 0 0 1 1 1 1 D123 TPR_19 PF14559.6 EGF81939.1 - 2.4e-12 47.2 0.0 9.4e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF81939.1 - 2.2e-07 30.4 0.0 0.028 14.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF81939.1 - 1.8e-06 27.6 0.0 0.023 14.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF81939.1 - 6.2e-05 22.9 0.0 0.24 11.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF81939.1 - 0.00016 21.3 0.0 0.0069 16.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF81939.1 - 0.00032 20.9 0.1 0.083 13.2 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF81939.1 - 0.0025 18.4 0.0 18 6.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGF81939.1 - 0.044 13.4 0.2 0.72 9.5 0.0 2.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 EGF81939.1 - 0.059 14.0 0.0 18 6.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF81939.1 - 0.13 13.1 0.0 18 6.5 0.0 3.2 2 2 2 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 EGF81940.1 - 2e-43 146.2 0.4 4.7e-17 61.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_L_2 PF13656.6 EGF81941.1 - 1.1e-26 92.4 0.2 1.5e-26 92.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGF81941.1 - 8.1e-10 38.0 0.0 1.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HTH_ParB PF17762.1 EGF81941.1 - 0.039 13.8 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 HTH domain found in ParB protein zf-CCCH_4 PF18044.1 EGF81942.1 - 0.0049 16.6 6.3 0.01 15.6 6.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGF81942.1 - 0.0098 15.8 5.5 0.019 14.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGF81942.1 - 0.055 13.5 8.0 0.1 12.7 8.0 1.4 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 EGF81942.1 - 0.069 13.8 0.6 0.21 12.3 0.6 1.9 1 0 0 1 1 1 0 Torus domain Med26 PF08711.11 EGF81942.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.9 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Alanine_zipper PF11839.8 EGF81943.1 - 9e-05 22.8 60.3 0.29 11.5 19.2 3.2 1 1 1 2 2 2 2 Alanine-zipper, major outer membrane lipoprotein Mitofilin PF09731.9 EGF81943.1 - 0.094 11.5 18.1 0.11 11.3 18.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Neur_chan_memb PF02932.16 EGF81943.1 - 0.17 11.9 4.1 0.31 11.1 4.1 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF966 PF06136.13 EGF81943.1 - 0.41 10.3 7.9 0.53 9.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4407 PF14362.6 EGF81943.1 - 1.2 8.4 12.9 1.7 8.0 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GARP PF16731.5 EGF81943.1 - 3.3 7.4 37.1 1.6 8.3 19.7 2.6 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Ank_4 PF13637.6 EGF81944.1 - 1.1e-37 128.0 12.1 4.2e-10 40.0 0.1 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF81944.1 - 6e-36 122.9 1.5 4.3e-12 46.4 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGF81944.1 - 3.1e-31 106.4 6.6 6.4e-05 23.2 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EGF81944.1 - 4.8e-31 106.4 8.9 1.7e-07 31.4 0.1 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF81944.1 - 4.2e-25 85.1 6.0 8.4e-05 22.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat DUF3447 PF11929.8 EGF81944.1 - 0.0094 15.9 0.1 0.25 11.3 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ribosomal_S6 PF01250.17 EGF81944.1 - 0.16 12.3 0.0 0.78 10.0 0.0 2.1 1 1 0 1 1 1 0 Ribosomal protein S6 MtN3_slv PF03083.16 EGF81945.1 - 2.4e-33 114.0 10.8 1.4e-19 69.9 3.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Popeye PF04831.13 EGF81945.1 - 0.18 12.0 0.3 0.18 12.0 0.3 2.2 1 1 2 3 3 3 0 Popeye protein conserved region DUF4191 PF13829.6 EGF81945.1 - 2.4 7.4 9.6 0.38 10.1 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4191) MtN3_slv PF03083.16 EGF81946.1 - 7.3e-33 112.5 9.1 4e-20 71.6 1.7 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Mito_carr PF00153.27 EGF81947.1 - 1.7e-71 236.2 0.6 6.2e-24 83.7 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.6 EGF81947.1 - 1.4e-05 24.8 0.0 0.35 10.8 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 EGF81947.1 - 0.013 16.0 0.0 0.17 12.4 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EGF81947.1 - 0.12 12.0 0.0 24 4.8 0.0 3.5 3 0 0 3 3 3 0 EF hand Tim17 PF02466.19 EGF81947.1 - 2.4 8.6 4.2 53 4.2 0.1 3.6 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TPR_19 PF14559.6 EGF81948.1 - 0.00062 20.2 0.0 0.0028 18.1 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF81948.1 - 0.001 19.0 0.9 20 5.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF5588 PF17826.1 EGF81948.1 - 0.0022 17.0 0.1 0.0026 16.7 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) ANAPC3 PF12895.7 EGF81948.1 - 0.011 16.0 2.1 0.38 11.0 1.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DLIC PF05783.11 EGF81950.1 - 2.4e-08 33.3 0.1 1.6e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 EGF81950.1 - 0.00033 20.9 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGF81950.1 - 0.013 15.1 0.0 0.094 12.3 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.6 EGF81950.1 - 0.056 13.7 0.7 1.6 9.0 0.1 3.1 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 EGF81950.1 - 0.075 12.4 0.2 12 5.2 0.0 2.3 2 0 0 2 2 2 0 KaiC TMF_TATA_bd PF12325.8 EGF81951.1 - 1.4e-27 96.2 9.6 1.4e-27 96.2 9.6 10.6 3 2 8 12 12 12 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EGF81951.1 - 3.8e-10 39.6 11.6 3.8e-10 39.6 11.6 12.8 5 5 8 13 13 13 2 TATA element modulatory factor 1 DNA binding IQ PF00612.27 EGF81951.1 - 5.1e-06 25.8 0.0 1.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cep57_CLD_2 PF14197.6 EGF81951.1 - 0.054 13.6 0.1 0.054 13.6 0.1 10.6 7 6 2 9 9 9 0 Centrosome localisation domain of PPC89 Acyl_transf_1 PF00698.21 EGF81952.1 - 2.2e-14 53.7 0.1 2.9e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Acyl transferase domain Phasin_2 PF09361.10 EGF81952.1 - 0.031 14.5 0.8 0.088 13.1 0.3 1.9 2 0 0 2 2 2 0 Phasin protein MCM PF00493.23 EGF81953.1 - 4.4e-102 339.9 0.0 1.2e-101 338.5 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGF81953.1 - 7.5e-31 106.6 4.4 1e-30 106.2 3.3 1.8 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EGF81953.1 - 9.1e-20 70.9 0.2 2.3e-19 69.6 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGF81953.1 - 2.7e-18 66.4 0.3 8.2e-18 64.9 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGF81953.1 - 4.3e-08 32.8 0.1 1.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGF81953.1 - 5e-07 29.8 0.0 1.3e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGF81953.1 - 0.025 14.5 0.1 0.086 12.7 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGF81953.1 - 0.057 13.1 0.0 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1732 PF08340.11 EGF81953.1 - 0.081 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) DUF2430 PF10353.9 EGF81954.1 - 0.12 12.8 0.1 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) PQ-loop PF04193.14 EGF81955.1 - 4.2e-30 103.3 9.8 4.8e-18 64.7 6.2 3.3 3 0 0 3 3 3 2 PQ loop repeat eIF-5_eIF-2B PF01873.17 EGF81956.1 - 2.9e-40 136.8 0.4 3.8e-40 136.4 0.4 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EGF81956.1 - 0.024 14.2 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 EGF81956.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) ThiF PF00899.21 EGF81957.1 - 4.9e-106 353.6 0.0 4.4e-70 235.8 0.0 2.4 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGF81957.1 - 1.3e-93 313.6 0.1 2.2e-93 312.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGF81957.1 - 1.2e-34 118.9 0.1 8.8e-34 116.1 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin fold domain E1_FCCH PF16190.5 EGF81957.1 - 1.6e-31 108.3 0.6 3.6e-31 107.2 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGF81957.1 - 1.4e-27 95.6 0.4 2.9e-27 94.6 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Tap-RNA_bind PF09162.10 EGF81957.1 - 0.16 11.8 0.5 1.7 8.5 0.0 3.0 4 0 0 4 4 4 0 Tap, RNA-binding APG6_N PF17675.1 EGF81958.1 - 4e-23 82.4 10.0 5.5e-23 82.0 10.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region APG6 PF04111.12 EGF81958.1 - 8.8e-12 45.3 0.0 1.6e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain WEMBL PF05701.11 EGF81958.1 - 0.0042 15.8 2.1 0.0053 15.5 2.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light BH3 PF15285.6 EGF81958.1 - 0.0098 15.6 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting FlaC_arch PF05377.11 EGF81958.1 - 2.1 8.8 4.6 5.5 7.5 0.8 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 EGF81958.1 - 3.4 6.2 5.0 4.7 5.7 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6 PF04111.12 EGF81959.1 - 2.5e-46 157.9 0.0 2.8e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Apg6 BARA domain V-ATPase_C PF03223.15 EGF81960.1 - 1.9e-130 435.6 1.8 2.1e-130 435.4 1.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EGF81960.1 - 0.036 14.7 1.4 0.89 10.2 0.1 2.6 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain DUF1494 PF07379.11 EGF81960.1 - 0.079 12.8 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) SCO1-SenC PF02630.14 EGF81961.1 - 1.9e-45 154.1 0.0 2.8e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EGF81961.1 - 1.6e-05 24.8 0.0 3.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGF81961.1 - 2.2e-05 24.7 0.0 4.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like GTP_EFTU PF00009.27 EGF81962.1 - 7.9e-64 214.8 0.2 1.3e-63 214.1 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGF81962.1 - 1.6e-39 134.4 0.1 3.4e-39 133.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGF81962.1 - 1.6e-32 111.4 0.0 3.4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGF81962.1 - 5.9e-23 80.7 0.0 1.5e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGF81962.1 - 9.5e-13 48.3 0.1 2.4e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGF81962.1 - 6.3e-07 29.3 0.0 2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGF81962.1 - 0.00047 20.2 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 EGF81962.1 - 0.019 15.4 0.0 0.27 11.7 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain AIG1 PF04548.16 EGF81962.1 - 0.021 14.1 0.0 0.061 12.6 0.0 1.7 1 0 0 1 1 1 0 AIG1 family NlpE_C PF17185.4 EGF81962.1 - 0.046 14.0 0.1 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 NlpE C-terminal OB domain FeoB_N PF02421.18 EGF81962.1 - 0.13 11.8 0.0 0.45 10.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B adh_short PF00106.25 EGF81963.1 - 1.9e-44 151.5 1.0 2.7e-44 151.0 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF81963.1 - 2.9e-28 99.0 0.0 3.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF81963.1 - 1.4e-08 34.8 0.3 9e-08 32.2 0.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF81963.1 - 0.021 14.3 0.1 0.03 13.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PglD_N PF17836.1 EGF81963.1 - 0.023 15.3 0.3 0.11 13.2 0.3 2.0 2 0 0 2 2 2 0 PglD N-terminal domain AAA_2 PF07724.14 EGF81965.1 - 6e-54 182.7 0.0 2.8e-51 174.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGF81965.1 - 5.1e-33 113.1 0.3 5.1e-33 113.1 0.3 3.1 3 1 0 3 3 2 1 AAA lid domain AAA PF00004.29 EGF81965.1 - 1.4e-27 96.7 0.0 2.5e-14 53.8 0.0 3.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGF81965.1 - 4.2e-21 74.8 3.1 8.6e-21 73.8 0.0 3.3 4 0 0 4 4 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGF81965.1 - 3.2e-19 69.3 1.7 2.5e-12 46.9 0.0 3.9 4 2 0 4 4 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 EGF81965.1 - 2.8e-15 56.2 3.1 2.5e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 EGF81965.1 - 2.3e-13 50.9 11.8 1.6e-07 31.9 0.0 5.2 6 1 0 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EGF81965.1 - 9.4e-09 35.2 0.1 1.9e-05 24.4 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGF81965.1 - 1.2e-08 34.9 0.1 0.0051 16.6 0.0 3.1 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EGF81965.1 - 4.2e-08 33.6 3.6 0.0024 18.1 0.1 4.6 3 2 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EGF81965.1 - 1.4e-06 28.0 0.0 0.025 14.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 EGF81965.1 - 3e-06 27.3 1.3 1.6 8.6 0.0 4.2 3 1 0 4 4 4 2 ATPase domain predominantly from Archaea TniB PF05621.11 EGF81965.1 - 3.6e-06 26.5 0.1 0.007 15.8 0.1 3.9 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 EGF81965.1 - 4.7e-06 26.7 0.1 0.1 12.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGF81965.1 - 8.6e-06 26.3 0.1 0.3 11.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGF81965.1 - 1.1e-05 24.9 0.1 0.25 10.7 0.1 3.9 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Roc PF08477.13 EGF81965.1 - 1.3e-05 25.4 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 EGF81965.1 - 1.4e-05 24.9 2.4 0.17 11.6 0.0 4.3 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGF81965.1 - 1.7e-05 25.2 0.0 0.24 11.8 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_24 PF13479.6 EGF81965.1 - 3.7e-05 23.5 0.1 0.011 15.5 0.0 3.0 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 EGF81965.1 - 4.8e-05 23.3 0.0 0.36 10.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain TsaE PF02367.17 EGF81965.1 - 0.00035 20.6 0.0 0.83 9.7 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 EGF81965.1 - 0.00088 19.1 0.0 0.014 15.2 0.0 2.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 EGF81965.1 - 0.00089 19.1 0.0 5.9 6.8 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGF81965.1 - 0.00099 19.3 0.0 1.9 8.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 EGF81965.1 - 0.0011 18.3 0.0 0.97 8.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain DUF87 PF01935.17 EGF81965.1 - 0.0014 18.8 2.8 0.1 12.7 0.0 3.7 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_25 PF13481.6 EGF81965.1 - 0.0018 17.9 0.1 0.17 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGF81965.1 - 0.0019 18.7 0.5 0.64 10.5 0.0 3.6 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EGF81965.1 - 0.0021 18.0 0.0 3.2 7.7 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 EGF81965.1 - 0.0023 17.3 0.2 2.2 7.5 0.0 3.0 3 0 0 3 3 2 1 Zeta toxin SRP54 PF00448.22 EGF81965.1 - 0.0036 17.0 0.0 1.7 8.3 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.6 EGF81965.1 - 0.0039 17.6 0.2 29 5.1 0.0 4.3 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 EGF81965.1 - 0.0054 16.7 0.0 0.79 9.6 0.0 2.7 2 0 0 2 2 2 1 NTPase DUF815 PF05673.13 EGF81965.1 - 0.0062 15.7 0.5 0.29 10.2 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGF81965.1 - 0.008 16.4 0.0 16 5.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain EzrA PF06160.12 EGF81965.1 - 0.012 13.8 6.9 0.031 12.5 6.3 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_30 PF13604.6 EGF81965.1 - 0.015 15.0 0.1 0.99 9.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EGF81965.1 - 0.022 14.8 0.0 6.1 6.8 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Csm2_III-A PF03750.13 EGF81965.1 - 0.049 14.5 1.6 3.3 8.6 0.7 2.7 2 0 0 2 2 2 0 Csm2 Type III-A NB-ARC PF00931.22 EGF81965.1 - 0.056 12.6 0.0 11 5.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Spc7 PF08317.11 EGF81965.1 - 0.065 12.1 5.1 0.13 11.2 5.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_19 PF13245.6 EGF81965.1 - 0.067 13.5 0.9 1.4 9.2 0.2 3.1 3 1 0 3 3 2 0 AAA domain FlxA PF14282.6 EGF81965.1 - 0.1 12.6 4.0 0.3 11.1 1.4 2.4 2 0 0 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 EGF81965.1 - 0.13 12.4 7.1 0.25 11.4 7.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 EGF81965.1 - 0.14 12.0 1.7 1.6 8.5 1.7 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.6 EGF81965.1 - 0.17 12.3 6.0 3.7 8.0 0.3 3.7 3 0 0 3 3 3 0 Snapin/Pallidin DUF4407 PF14362.6 EGF81965.1 - 0.24 10.7 6.6 0.52 9.6 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_29 PF13555.6 EGF81965.1 - 0.62 9.9 2.2 25 4.7 0.0 3.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain Atg14 PF10186.9 EGF81965.1 - 0.69 8.9 6.4 1.4 8.0 6.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 EGF81965.1 - 0.99 9.9 4.0 1.7 9.2 0.2 3.4 3 1 0 3 3 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EGF81965.1 - 1.2 9.5 3.7 7.8 6.9 3.0 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 EGF81965.1 - 2.1 8.4 8.4 0.8 9.8 4.8 2.1 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 EGF81965.1 - 3.2 8.5 4.8 2.8 8.7 2.4 2.2 2 0 0 2 2 1 0 Occludin homology domain YlqD PF11068.8 EGF81965.1 - 4.6 7.6 6.6 3.3 8.1 3.5 2.2 1 1 1 2 2 2 0 YlqD protein AAA_23 PF13476.6 EGF81965.1 - 7.5 7.0 17.9 9.7 6.6 0.0 4.5 4 1 0 4 4 2 0 AAA domain DUF724 PF05266.14 EGF81965.1 - 8.7 6.1 7.5 14 5.5 3.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 EGF81965.1 - 9.7 6.5 14.0 2.9 8.2 2.8 3.3 1 1 3 4 4 4 0 ABC transporter C-terminal domain adh_short PF00106.25 EGF81966.1 - 1.7e-12 47.2 0.5 5.7e-10 39.0 0.5 3.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF81966.1 - 4.3e-05 23.2 0.0 0.0045 16.6 0.0 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EGF81966.1 - 0.00017 20.9 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 EGF81966.1 - 0.00052 19.5 0.0 0.082 12.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGF81966.1 - 0.053 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EGF81966.1 - 0.11 11.6 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ubiquitin PF00240.23 EGF81967.1 - 1.6e-27 95.0 0.1 1.8e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGF81967.1 - 3e-16 59.0 0.1 3.3e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGF81967.1 - 6.7e-05 22.7 0.0 8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EGF81967.1 - 0.0003 21.2 0.0 0.0011 19.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGF81967.1 - 0.062 13.4 0.5 5 7.2 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain SAP PF02037.27 EGF81968.1 - 7.7e-12 44.7 1.5 1.5e-11 43.8 1.5 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EGF81968.1 - 0.0088 15.7 0.2 0.0088 15.7 0.2 2.5 3 1 0 3 3 3 1 HeH/LEM domain DUF3275 PF11679.8 EGF81968.1 - 1.3 9.0 5.8 0.92 9.5 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) MORN PF02493.20 EGF81970.1 - 3.6e-16 58.0 25.6 1e-07 31.4 2.0 6.1 6 0 0 6 6 6 5 MORN repeat Syja_N PF02383.18 EGF81971.1 - 4.5e-92 308.8 0.6 6.7e-92 308.2 0.6 1.3 1 0 0 1 1 1 1 SacI homology domain Beta_protein PF14350.6 EGF81971.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta protein CLIP_SPH_Scar PF18399.1 EGF81971.1 - 0.17 12.0 0.3 0.4 10.8 0.3 1.5 1 0 0 1 1 1 0 Clip-domain serine protease homolog Scarface Syja_N PF02383.18 EGF81972.1 - 1.2e-74 251.6 0.6 1.8e-74 251.0 0.6 1.3 1 0 0 1 1 1 1 SacI homology domain LRR_6 PF13516.6 EGF81973.1 - 2.2e-17 61.6 26.2 2.9e-06 26.9 0.9 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EGF81973.1 - 0.00022 21.5 11.7 0.022 15.2 0.4 5.1 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF81973.1 - 0.00062 20.0 1.6 6.2 7.8 0.0 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EGF81973.1 - 0.048 13.4 11.1 3.7 7.4 0.0 5.1 4 1 0 4 4 4 0 Leucine rich repeat AAA_7 PF12775.7 EGF81973.1 - 0.074 12.6 0.1 9.8 5.6 0.1 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TRPM_tetra PF16519.5 EGF81973.1 - 0.11 12.6 0.1 3.5 7.8 0.0 3.1 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Ecl1 PF12855.7 EGF81974.1 - 0.00062 21.0 27.0 0.0013 20.0 27.0 1.8 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 EGF81974.1 - 0.011 16.4 2.1 0.029 15.0 2.1 1.7 1 0 0 1 1 1 0 PLATZ transcription factor Spectrin_like PF18373.1 EGF81974.1 - 0.081 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Spectrin like domain zf-MYND PF01753.18 EGF81974.1 - 0.3 11.2 3.0 0.78 9.9 3.0 1.8 1 1 0 1 1 1 0 MYND finger Tom6 PF17112.5 EGF81975.1 - 0.07 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Gly_transf_sug PF04488.15 EGF81976.1 - 3.4e-16 59.7 0.2 6e-16 58.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ABC_tran PF00005.27 EGF81977.1 - 2.2e-26 93.0 0.0 4.4e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGF81977.1 - 6e-18 65.1 27.3 9e-18 64.5 27.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGF81977.1 - 3.7e-11 43.4 0.0 2.4e-07 30.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF81977.1 - 0.005 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGF81977.1 - 0.038 14.5 0.1 0.066 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGF81977.1 - 0.039 13.9 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EGF81977.1 - 0.15 11.7 0.0 0.84 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A_type_inc PF04508.12 EGF81978.1 - 0.034 14.0 6.1 16 5.6 0.4 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat YpjP PF14005.6 EGF81978.1 - 0.034 14.2 2.1 7.9 6.5 0.7 3.3 1 1 2 3 3 3 0 YpjP-like protein TolA_bind_tri PF16331.5 EGF81978.1 - 0.046 13.8 8.4 20 5.3 0.3 4.5 4 1 0 4 4 4 0 TolA binding protein trimerisation DUF1098 PF06497.11 EGF81978.1 - 0.098 13.1 2.9 73 3.9 0.1 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1098) PspB PF06667.12 EGF81978.1 - 0.17 11.9 2.4 87 3.3 0.0 4.3 4 0 0 4 4 4 0 Phage shock protein B Rootletin PF15035.6 EGF81978.1 - 0.37 10.8 12.0 5.3 7.0 1.6 3.6 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion ARGLU PF15346.6 EGF81978.1 - 0.89 9.4 8.6 0.53 10.2 5.4 2.2 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 CbiG_C PF01890.16 EGF81979.1 - 0.17 12.4 0.8 0.23 12.0 0.4 1.4 1 1 0 1 1 1 0 Cobalamin synthesis G C-terminus IstB_IS21 PF01695.17 EGF81981.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sec2p PF06428.11 EGF81982.1 - 0.12 12.4 2.4 10 6.2 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF81982.1 - 0.9 9.7 3.8 19 5.4 3.8 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Asp PF00026.23 EGF81983.1 - 2.8e-13 50.0 0.2 1.9e-12 47.2 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF81983.1 - 0.0068 16.2 0.0 0.035 13.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal AAA_22 PF13401.6 EGF81985.1 - 0.0026 18.0 0.0 0.023 15.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain Arm_vescicular PF18770.1 EGF81986.1 - 0.69 9.9 3.5 1.1 9.2 0.5 2.4 1 1 1 2 2 2 0 Armadillo tether-repeat of vescicular transport factor Hormone_6 PF00236.18 EGF81990.1 - 0.05 13.6 1.2 0.11 12.4 1.2 1.6 1 0 0 1 1 1 0 Glycoprotein hormone DUF4246 PF14033.6 EGF81992.1 - 1.8e-29 103.2 0.0 2.4e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ndc1_Nup PF09531.10 EGF81994.1 - 0.18 10.4 9.5 0.2 10.3 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WDCP PF15390.6 EGF81994.1 - 0.63 8.4 4.2 0.97 7.7 4.2 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Hid1 PF12722.7 EGF81994.1 - 3.6 5.6 8.8 4.8 5.2 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPESP1 PF15754.5 EGF81995.1 - 0.0086 15.3 3.2 0.015 14.5 3.2 1.3 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 Terminase_4 PF05119.12 EGF81995.1 - 0.039 14.4 1.7 0.091 13.2 1.7 1.5 1 0 0 1 1 1 0 Phage terminase, small subunit Asp PF00026.23 EGF81998.1 - 1.8e-15 57.2 0.0 2.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF81998.1 - 2.2e-07 30.8 0.0 7.4e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal V-ATPase_G_2 PF16999.5 EGF81999.1 - 0.0039 17.6 2.9 0.091 13.2 3.3 2.3 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit DUF4709 PF15821.5 EGF81999.1 - 0.045 14.0 5.0 0.14 12.5 2.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) zf-SAP30 PF13866.6 EGF81999.1 - 0.07 13.2 4.5 1.7 8.8 0.0 3.3 3 0 0 3 3 3 0 SAP30 zinc-finger D5_N PF08706.11 EGF81999.1 - 0.11 12.8 2.9 0.24 11.7 2.9 1.6 1 0 0 1 1 1 0 D5 N terminal like Phage_Mu_Gam PF07352.12 EGF81999.1 - 0.36 10.7 5.5 0.8 9.6 1.3 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Nbl1_Borealin_N PF10444.9 EGF81999.1 - 0.37 10.5 5.9 0.31 10.7 2.8 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal PG_binding_3 PF09374.10 EGF81999.1 - 0.45 10.8 2.3 9 6.6 0.4 2.8 3 0 0 3 3 3 0 Predicted Peptidoglycan domain RRM_1 PF00076.22 EGF82001.1 - 3e-23 81.4 0.1 6.8e-12 45.0 0.0 2.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF82001.1 - 1.8e-11 43.7 0.0 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF82001.1 - 3.3e-07 30.1 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif NOA36 PF06524.12 EGF82001.1 - 0.17 11.2 3.7 0.25 10.6 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein DSPc PF00782.20 EGF82003.1 - 2.2e-29 101.9 0.0 2.6e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF82003.1 - 0.0047 16.5 0.0 0.0052 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGF82003.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Inhibitor_I9 PF05922.16 EGF82004.1 - 4.6e-05 24.0 0.0 4.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 CWC25 PF12542.8 EGF82005.1 - 1e-21 77.7 0.0 1e-21 77.7 0.0 5.0 2 2 2 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGF82005.1 - 9.9e-15 54.5 8.2 9.9e-15 54.5 8.2 4.6 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA_21 PF13304.6 EGF82005.1 - 3.9 7.2 9.0 7.2 6.3 7.6 2.1 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system zf-H2C2_2 PF13465.6 EGF82006.1 - 2.8e-10 40.1 21.9 1.3e-05 25.4 0.8 4.7 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 EGF82006.1 - 2e-09 37.4 42.5 2.9e-05 24.3 3.1 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGF82006.1 - 2.1e-07 30.7 20.5 0.0047 16.9 6.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGF82006.1 - 1.5e-05 25.4 32.7 0.024 15.5 1.9 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EGF82006.1 - 0.012 15.7 8.6 0.042 14.0 2.0 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 EGF82006.1 - 0.018 14.8 0.2 0.018 14.8 0.2 4.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGF82006.1 - 0.044 14.1 0.5 0.044 14.1 0.5 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 EGF82006.1 - 0.14 12.3 5.7 6.1 7.0 0.1 3.3 2 1 1 3 3 3 0 Zic proteins zinc finger domain RskA PF10099.9 EGF82006.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA zf-met PF12874.7 EGF82006.1 - 1 9.9 21.3 0.85 10.1 0.9 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type RNA_pol_Rpb1_5 PF04998.17 EGF82007.1 - 3.3e-94 315.3 0.1 6.4e-94 314.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGF82007.1 - 2.6e-64 216.4 0.1 6e-64 215.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGF82007.1 - 3.6e-32 111.5 0.0 2.6e-31 108.7 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGF82007.1 - 1e-31 110.4 0.4 5.5e-29 101.5 0.5 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGF82007.1 - 1.2e-22 79.8 0.1 3.5e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 YozE_SAM_like PF06855.12 EGF82007.1 - 0.075 13.2 0.5 0.28 11.4 0.1 2.1 2 0 0 2 2 2 0 YozE SAM-like fold Metallophos_2 PF12850.7 EGF82008.1 - 5.4e-17 62.5 0.0 7.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGF82008.1 - 0.00096 19.7 0.6 0.29 11.6 0.3 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Asp PF00026.23 EGF82009.1 - 4.2e-07 29.7 0.9 1.2e-06 28.2 0.9 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGF82009.1 - 0.00095 19.8 0.0 0.04 14.6 0.0 3.1 4 0 0 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 EGF82009.1 - 0.0051 17.3 0.0 0.12 12.9 0.0 3.1 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease Rhomboid PF01694.22 EGF82010.1 - 4.3e-28 98.2 5.1 4.3e-28 98.2 5.1 1.9 2 0 0 2 2 2 1 Rhomboid family Sel1 PF08238.12 EGF82011.1 - 2.4e-17 63.0 5.9 4.5e-08 33.5 0.2 4.3 4 0 0 4 4 4 3 Sel1 repeat zf-B_box PF00643.24 EGF82012.1 - 7.7e-08 32.4 8.8 7.7e-08 32.4 8.8 3.0 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 EGF82012.1 - 6e-06 26.4 0.3 2e-05 24.7 0.3 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.6 EGF82012.1 - 0.00086 19.1 7.4 0.00086 19.1 7.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF82012.1 - 0.0011 19.3 6.6 0.0011 19.3 6.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGF82012.1 - 0.004 17.0 5.1 0.004 17.0 5.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGF82012.1 - 0.082 13.1 0.3 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-RING_6 PF14835.6 EGF82012.1 - 0.22 11.4 1.4 0.53 10.2 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE_2 PF02318.16 EGF82012.1 - 1.9 8.7 8.6 14 6.0 2.2 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-ANAPC11 PF12861.7 EGF82012.1 - 2 8.5 7.9 0.82 9.8 1.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Septin PF00735.18 EGF82013.1 - 7.3e-46 156.7 0.0 9.1e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Septin TFIIF_alpha PF05793.12 EGF82014.1 - 5.2 5.5 6.1 6.1 5.3 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C2H2 PF00096.26 EGF82015.1 - 3.1e-10 39.9 4.6 0.00039 20.7 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGF82015.1 - 0.0023 18.2 0.8 0.0068 16.7 0.8 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EGF82015.1 - 0.0029 18.0 3.3 0.023 15.1 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF82015.1 - 0.0037 18.0 10.7 0.077 13.9 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 EGF82015.1 - 4.6 7.9 6.6 15 6.3 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain Peptidase_M28 PF04389.17 EGF82016.1 - 1.1e-36 126.4 0.0 1.7e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGF82016.1 - 0.045 12.8 0.1 0.77 8.7 0.0 2.6 2 1 1 3 3 3 0 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 EGF82016.1 - 0.064 13.0 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Ribosomal_S15 PF00312.22 EGF82017.1 - 2e-25 88.8 0.1 2e-25 88.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 OrfB_IS605 PF01385.19 EGF82017.1 - 1.7 8.9 5.6 0.31 11.3 0.4 2.3 3 0 0 3 3 3 0 Probable transposase Choline_sulf_C PF12411.8 EGF82018.1 - 0.067 13.0 0.1 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal MFAP1 PF06991.11 EGF82019.1 - 2.9e-66 223.4 18.7 2.9e-66 223.4 18.7 2.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing EBV-NA3 PF05009.12 EGF82019.1 - 0.1 12.1 3.0 0.66 9.5 3.7 2.0 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Sel1 PF08238.12 EGF82020.1 - 4.7e-102 332.1 46.4 6.5e-09 36.2 0.3 14.5 14 1 0 14 14 14 13 Sel1 repeat TPR_17 PF13431.6 EGF82020.1 - 0.0021 18.3 4.0 2.8 8.5 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat DPBB_1 PF03330.18 EGF82020.1 - 0.3 11.4 2.0 7.8 6.9 0.1 2.8 2 0 0 2 2 2 0 Lytic transglycolase Sel1 PF08238.12 EGF82021.1 - 0.0091 16.7 0.0 0.016 15.9 0.0 1.4 1 0 0 1 1 1 1 Sel1 repeat Rab3-GTPase_cat PF13890.6 EGF82022.1 - 1.1e-56 191.0 2.1 1.6e-56 190.4 0.9 2.0 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit Glyco_transf_8 PF01501.20 EGF82023.1 - 2.1e-22 79.9 0.0 9.1e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Acyl-CoA_dh_1 PF00441.24 EGF82024.1 - 7.8e-46 156.0 0.9 1.4e-45 155.2 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGF82024.1 - 7e-26 91.1 0.0 1.6e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGF82024.1 - 2.6e-25 88.4 0.0 4.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGF82024.1 - 5.2e-20 72.1 0.5 8.7e-20 71.4 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Antimicrobial_8 PF08103.11 EGF82025.1 - 0.095 12.9 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 Uperin family MSC PF09402.10 EGF82026.1 - 4.1e-26 92.2 0.0 5.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain CEP170_C PF15308.6 EGF82028.1 - 0.0019 16.9 0.6 0.0021 16.7 0.6 1.1 1 0 0 1 1 1 1 CEP170 C-terminus PMC2NT PF08066.12 EGF82029.1 - 4.4 8.1 11.2 8.5 7.2 0.3 3.6 2 1 1 3 3 3 0 PMC2NT (NUC016) domain WDCP PF15390.6 EGF82029.1 - 9 4.5 14.5 14 3.9 14.5 1.3 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Asp PF00026.23 EGF82030.1 - 3.1e-12 46.6 0.1 6.1e-12 45.6 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82030.1 - 4.1e-05 23.4 0.1 0.00032 20.5 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Diacid_rec PF05651.13 EGF82030.1 - 0.047 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Putative sugar diacid recognition ING PF12998.7 EGF82031.1 - 0.029 15.0 0.8 0.052 14.2 0.8 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DALR_1 PF05746.15 EGF82031.1 - 0.09 13.0 0.5 0.13 12.4 0.5 1.3 1 0 0 1 1 1 0 DALR anticodon binding domain WDCP PF15390.6 EGF82031.1 - 0.12 10.8 0.8 0.14 10.6 0.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Asp PF00026.23 EGF82032.1 - 3.8e-16 59.4 0.0 6.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82032.1 - 7.7e-05 22.5 0.0 0.0003 20.6 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Sec2p PF06428.11 EGF82033.1 - 0.00086 19.2 3.9 0.037 14.0 0.2 2.3 1 1 1 2 2 2 2 GDP/GTP exchange factor Sec2p DUF4686 PF15742.5 EGF82033.1 - 0.0066 15.6 4.6 0.0086 15.3 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) DASH_Duo1 PF08651.10 EGF82033.1 - 0.011 15.5 0.4 0.023 14.4 0.4 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF3517 PF12030.8 EGF82033.1 - 0.012 14.5 1.2 0.018 14.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) SbsC_C PF18058.1 EGF82033.1 - 0.024 14.9 0.5 0.036 14.3 0.5 1.3 1 0 0 1 1 1 0 SbsC C-terminal domain CLZ PF16526.5 EGF82033.1 - 0.064 13.6 3.4 1.1 9.7 0.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3368 PF11848.8 EGF82033.1 - 0.067 13.0 0.1 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) HOOK PF05622.12 EGF82033.1 - 0.11 10.6 6.8 0.15 10.2 6.8 1.0 1 0 0 1 1 1 0 HOOK protein Prefoldin PF02996.17 EGF82033.1 - 0.23 11.4 3.6 0.4 10.6 0.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit THOC7 PF05615.13 EGF82033.1 - 0.4 11.0 8.3 7.1 6.9 8.3 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 Uds1 PF15456.6 EGF82033.1 - 0.43 10.7 5.8 0.83 9.8 5.8 1.5 1 0 0 1 1 1 0 Up-regulated During Septation MerR-DNA-bind PF09278.11 EGF82033.1 - 0.51 10.9 5.4 0.68 10.5 0.6 2.2 2 0 0 2 2 2 0 MerR, DNA binding SlyX PF04102.12 EGF82033.1 - 0.54 10.9 3.8 2.2 9.0 0.7 2.2 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 EGF82033.1 - 0.76 7.6 3.1 0.99 7.2 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC-167 PF15188.6 EGF82033.1 - 0.81 10.1 5.2 1.4 9.3 5.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 NYD-SP28 PF14772.6 EGF82033.1 - 1.8 8.7 11.1 4.5 7.4 11.1 1.6 1 1 0 1 1 1 0 Sperm tail ADIP PF11559.8 EGF82033.1 - 1.8 8.6 9.0 7.6 6.6 1.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 EGF82033.1 - 2.2 8.7 13.5 3 8.3 2.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Fungal_trans_2 PF11951.8 EGF82034.1 - 0.051 12.4 0.2 0.066 12.0 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain IQCJ-SCHIP1 PF15157.6 EGF82034.1 - 0.44 10.4 3.5 1.7 8.5 2.5 2.3 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif SPATA1_C PF15743.5 EGF82034.1 - 1.2 9.2 8.2 0.13 12.3 4.0 1.6 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Clat_adaptor_s PF01217.20 EGF82035.1 - 7.9e-46 155.5 0.1 8.8e-46 155.4 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rpn3_C PF08375.11 EGF82036.1 - 8.6e-24 83.7 0.0 1.8e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EGF82036.1 - 3.7e-21 75.6 0.5 2.8e-19 69.6 0.1 3.2 3 0 0 3 3 3 1 PCI domain Kelch_4 PF13418.6 EGF82037.1 - 1e-25 89.4 6.1 2.2e-11 43.5 0.1 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGF82037.1 - 4.7e-24 84.1 2.3 1.3e-08 34.9 0.0 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGF82037.1 - 6.6e-22 77.1 0.7 1.8e-05 24.6 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGF82037.1 - 1.1e-19 69.9 5.5 1.1e-05 25.5 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGF82037.1 - 3.2e-18 65.0 1.6 0.0005 19.6 0.8 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGF82037.1 - 3.8e-17 61.5 5.9 0.00017 21.4 0.4 4.9 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 EGF82037.1 - 2.8e-13 50.1 0.0 4.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EGF82037.1 - 0.1 12.7 0.1 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch FKBP_C PF00254.28 EGF82038.1 - 4.1e-24 84.7 0.0 6.3e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 EGF82038.1 - 2e-23 82.0 0.4 2.9e-23 81.5 0.4 1.3 1 0 0 1 1 1 1 Basic tilted helix bundle domain Pro_isomerase PF00160.21 EGF82039.1 - 3.4e-49 167.1 0.4 4.5e-49 166.8 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SKIP_SNW PF02731.15 EGF82040.1 - 3.4e-72 241.4 1.1 3.4e-72 241.4 1.1 2.1 2 0 0 2 2 2 1 SKIP/SNW domain Peptidase_C58 PF03543.14 EGF82040.1 - 4.5 6.9 6.8 1.6 8.4 2.4 2.3 1 1 1 2 2 2 0 Yersinia/Haemophilus virulence surface antigen PALP PF00291.25 EGF82041.1 - 3.9e-80 269.4 0.1 4.8e-80 269.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGF82041.1 - 9.9e-37 124.6 0.0 3.2e-18 65.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Pkinase PF00069.25 EGF82043.1 - 9.9e-55 185.7 0.0 6e-39 134.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82043.1 - 1.7e-24 86.5 0.0 3.1e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82043.1 - 6.6e-07 28.9 0.0 1.8e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF82043.1 - 0.00029 19.9 0.1 0.00052 19.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGF82043.1 - 0.0022 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGF82043.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF82043.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF82043.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 EGF82045.1 - 5.4e-79 264.2 16.1 1.8e-41 141.8 3.2 3.1 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF82045.1 - 3.3e-62 210.1 13.3 1.2e-33 116.6 3.7 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EGF82045.1 - 2.8e-31 107.7 0.0 6.4e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EGF82045.1 - 2.4e-28 99.3 9.4 3.6e-14 53.1 1.5 2.3 2 0 0 2 2 2 2 KR domain SCP2 PF02036.17 EGF82045.1 - 4.7e-23 81.6 0.2 1.4e-22 80.1 0.2 1.9 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGF82045.1 - 0.00015 22.0 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal MaoC_dehydrat_N PF13452.6 EGF82045.1 - 0.00038 20.6 0.0 0.0052 16.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 EGF82045.1 - 0.0019 17.5 1.4 0.34 10.2 0.2 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PglL_A PF15864.5 EGF82045.1 - 3.5 7.4 8.0 12 5.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase RRM_1 PF00076.22 EGF82046.1 - 4.6e-17 61.6 0.2 7.7e-09 35.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EGF82046.1 - 5.8e-15 54.9 1.8 1.4e-14 53.6 1.8 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF82046.1 - 8.6e-08 32.2 0.5 2.2e-07 30.9 0.5 1.7 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 EGF82046.1 - 0.00013 21.2 6.4 0.00033 19.9 6.4 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_2 PF12756.7 EGF82046.1 - 0.0022 18.3 0.8 0.0069 16.7 0.8 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGF82046.1 - 0.0079 16.5 1.1 0.019 15.2 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding HypA PF01155.19 EGF82046.1 - 0.015 15.3 0.6 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ALC PF17527.2 EGF82046.1 - 0.036 13.7 0.6 0.068 12.8 0.6 1.4 1 0 0 1 1 1 0 Phage ALC protein zf-C2H2_4 PF13894.6 EGF82046.1 - 0.21 12.5 0.2 0.21 12.5 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DSBA PF01323.20 EGF82047.1 - 3.5e-32 111.8 0.0 4e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGF82047.1 - 0.0024 18.1 0.1 0.0087 16.2 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin Raptor_N PF14538.6 EGF82048.1 - 9.8e-55 184.5 0.5 2.2e-54 183.4 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGF82048.1 - 5.1e-10 39.8 0.6 0.13 13.2 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 EGF82048.1 - 1.1e-07 31.5 3.0 0.048 13.9 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGF82048.1 - 5.8e-06 26.4 0.1 2.1e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF82048.1 - 2.2e-05 24.8 0.1 0.00048 20.5 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats ANAPC4_WD40 PF12894.7 EGF82048.1 - 7.2e-05 23.0 0.0 1.8 8.9 0.0 4.8 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGF82048.1 - 0.00012 22.1 0.1 1.3 9.1 0.0 3.6 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region HEAT_EZ PF13513.6 EGF82048.1 - 0.0005 20.5 1.8 0.011 16.2 0.1 3.1 3 0 0 3 3 3 1 HEAT-like repeat Atx10homo_assoc PF09759.9 EGF82048.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 EGF82048.1 - 0.26 11.9 0.5 1.6 9.4 0.0 2.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Glyco_hydro_16 PF00722.21 EGF82050.1 - 7.9e-23 80.8 0.1 1.2e-22 80.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 EGF82051.1 - 1.1e-23 83.6 0.3 1.7e-23 83.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HAP1_N PF04849.13 EGF82052.1 - 4.2e-05 22.9 6.5 5.7e-05 22.5 6.5 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region BBP1_C PF15272.6 EGF82052.1 - 0.0077 16.1 0.7 1.8 8.4 0.0 2.4 2 0 0 2 2 2 2 Spindle pole body component BBP1, C-terminal Prefoldin_3 PF13758.6 EGF82052.1 - 0.046 13.8 0.0 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Prefoldin subunit ANTH PF07651.16 EGF82052.1 - 0.095 11.7 0.1 0.14 11.1 0.1 1.3 1 1 0 1 1 1 0 ANTH domain RAP1 PF07218.11 EGF82052.1 - 0.12 10.7 3.3 0.13 10.5 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YabA PF06156.13 EGF82052.1 - 0.18 12.5 0.1 0.18 12.5 0.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA ATF7IP_BD PF16788.5 EGF82052.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 ATF-interacting protein binding domain USP8_interact PF08941.10 EGF82052.1 - 0.3 10.9 1.1 0.5 10.2 1.0 1.4 1 1 0 1 1 1 0 USP8 interacting CENP-H PF05837.12 EGF82052.1 - 2.5 8.6 7.1 4 7.9 4.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TSC22 PF01166.18 EGF82052.1 - 4.5 7.7 7.4 3.2 8.1 0.6 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family DnaJ PF00226.31 EGF82053.1 - 1.7e-24 85.7 1.0 2e-24 85.5 1.0 1.0 1 0 0 1 1 1 1 DnaJ domain DUF1340 PF07067.11 EGF82053.1 - 0.064 12.6 0.0 0.064 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Pkinase PF00069.25 EGF82054.1 - 1.8e-12 47.2 0.0 9.9e-12 44.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF82054.1 - 3.5e-05 23.9 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF82054.1 - 0.0025 17.4 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF82054.1 - 0.004 16.8 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF82054.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF82054.1 - 0.0069 16.0 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF82054.1 - 0.0086 14.9 0.8 0.012 14.5 0.8 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF82054.1 - 0.0095 15.2 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-PolyVal PF18762.1 EGF82054.1 - 0.029 14.3 0.5 0.55 10.2 0.1 2.4 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins YrbL-PhoP_reg PF10707.9 EGF82054.1 - 0.03 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Peptidase_S41 PF03572.18 EGF82057.1 - 2.8e-12 46.5 0.0 5.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 TFIIA PF03153.13 EGF82058.1 - 0.026 14.5 17.6 0.037 14.0 17.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OPT PF03169.15 EGF82060.1 - 5.6e-128 428.3 46.9 6.8e-128 428.0 46.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DLH PF01738.18 EGF82061.1 - 1.3e-42 145.8 0.5 1.5e-42 145.6 0.5 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGF82061.1 - 0.00023 21.1 1.1 0.021 14.7 0.1 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGF82061.1 - 0.0021 18.7 0.1 0.04 14.5 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGF82061.1 - 0.003 17.4 0.2 0.065 13.1 0.1 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGF82061.1 - 0.055 13.1 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PPR_2 PF13041.6 EGF82062.1 - 6.7e-27 93.4 7.3 2.5e-08 34.0 0.0 8.6 6 3 3 9 9 9 5 PPR repeat family PPR PF01535.20 EGF82062.1 - 9.5e-17 60.0 10.3 0.051 13.8 0.1 8.6 10 0 0 10 10 10 5 PPR repeat PPR_3 PF13812.6 EGF82062.1 - 8e-15 54.7 0.0 0.0039 17.2 0.0 6.0 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF82062.1 - 2e-08 33.7 1.6 0.065 12.9 0.0 5.3 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EGF82062.1 - 4.7e-07 29.4 0.2 3.3e-06 26.6 0.1 2.4 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EGF82062.1 - 0.041 14.3 0.3 6.7 7.1 0.0 3.9 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 EGF82062.1 - 0.098 13.5 0.0 2.2 9.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S16 PF00886.19 EGF82063.1 - 3.1e-26 91.2 0.0 4e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 PPR_2 PF13041.6 EGF82064.1 - 3.4e-15 56.0 3.2 0.0053 16.9 0.0 8.6 9 1 1 10 10 10 3 PPR repeat family PPR PF01535.20 EGF82064.1 - 2.3e-09 36.8 4.3 0.24 11.7 0.0 9.2 11 0 0 11 11 11 2 PPR repeat PPR_3 PF13812.6 EGF82064.1 - 2.9e-06 27.3 0.0 2.8 8.1 0.0 5.7 6 1 1 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF82064.1 - 4.3e-06 26.3 1.2 4 7.2 0.0 6.4 6 1 0 6 6 6 2 PPR repeat DUF3368 PF11848.8 EGF82064.1 - 0.0021 17.8 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) PPR_long PF17177.4 EGF82064.1 - 0.0027 17.1 0.4 3 7.2 0.0 3.8 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EGF82064.1 - 0.0032 18.1 0.0 42 5.3 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat ATP13 PF12921.7 EGF82064.1 - 0.014 15.2 0.5 10 6.0 0.0 4.9 4 1 1 5 5 5 0 Mitochondrial ATPase expression FA_hydroxylase PF04116.13 EGF82065.1 - 8.5e-20 71.5 26.7 8.5e-20 71.5 26.7 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily BAR PF03114.18 EGF82066.1 - 1.8e-46 158.8 1.6 2.1e-46 158.5 1.6 1.0 1 0 0 1 1 1 1 BAR domain APG17 PF04108.12 EGF82066.1 - 0.024 13.7 0.4 0.038 13.1 0.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF99 PF01949.16 EGF82066.1 - 0.039 13.4 0.9 0.072 12.5 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF99 BRE1 PF08647.11 EGF82066.1 - 0.045 13.8 2.2 0.96 9.6 0.1 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3958 PF13125.6 EGF82066.1 - 0.12 12.6 3.3 0.13 12.5 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) ADIP PF11559.8 EGF82066.1 - 0.66 10.1 4.7 4.3 7.4 0.4 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IMD PF08397.11 EGF82066.1 - 1.6 8.1 5.3 2.3 7.6 0.5 2.2 1 1 1 2 2 2 0 IRSp53/MIM homology domain zf-U1 PF06220.12 EGF82067.1 - 7.5e-13 48.0 1.9 7.5e-13 48.0 1.9 1.7 2 0 0 2 2 2 1 U1 zinc finger POTRA_2 PF08479.11 EGF82067.1 - 0.021 14.7 0.0 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 POTRA domain, ShlB-type PRKCSH-like PF12999.7 EGF82068.1 - 6.1e-42 143.4 5.3 6.1e-42 143.4 5.3 2.8 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGF82068.1 - 3.1e-30 104.9 1.0 3.1e-30 104.9 1.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein NPIP PF06409.11 EGF82068.1 - 0.024 13.7 0.8 0.037 13.1 0.8 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) LIM PF00412.22 EGF82069.1 - 1.8e-07 31.3 4.3 2.7e-07 30.7 4.3 1.2 1 0 0 1 1 1 1 LIM domain SNARE PF05739.19 EGF82070.1 - 6.1e-15 55.0 1.0 1.1e-14 54.1 1.0 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EGF82070.1 - 0.00063 18.9 0.0 0.0085 15.3 0.0 2.6 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 EGF82070.1 - 0.047 13.9 0.5 0.69 10.2 0.0 3.1 3 2 1 4 4 4 0 SNARE-complex protein Syntaxin-18 N-terminus Pox_EPC_I2-L1 PF12575.8 EGF82070.1 - 0.093 13.0 2.1 21 5.5 0.0 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 YvbH_ext PF11724.8 EGF82070.1 - 0.1 12.9 0.5 0.33 11.3 0.5 1.8 1 0 0 1 1 1 0 YvbH-like oligomerisation region DUF1664 PF07889.12 EGF82070.1 - 0.19 11.8 6.5 4.7 7.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin PF00804.25 EGF82070.1 - 0.4 10.3 7.6 1.6 8.4 0.1 3.1 2 2 1 3 3 3 0 Syntaxin SET PF00856.28 EGF82071.1 - 1.3e-12 48.4 0.0 2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 SET domain SRP_TPR_like PF17004.5 EGF82071.1 - 0.071 13.1 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative TPR-like repeat DUF4639 PF15479.6 EGF82073.1 - 1.9e-14 53.6 1.3 1.9e-14 53.6 1.3 2.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4639) DUF3761 PF12587.8 EGF82074.1 - 0.26 11.7 1.5 0.77 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) Herpes_UL52 PF03121.15 EGF82076.1 - 3.7e-10 39.6 0.8 9.2e-10 38.3 0.8 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase DUF4884 PF16225.5 EGF82076.1 - 7.8 6.7 7.4 15 5.8 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4884) Phi_1 PF04674.12 EGF82077.1 - 2.1e-35 122.4 3.5 6.2e-35 120.8 3.5 1.8 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region IFRD PF05004.13 EGF82079.1 - 6.1e-41 140.5 0.0 7.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 EGF82079.1 - 0.00063 20.3 0.9 0.0019 18.7 0.0 2.1 2 0 0 2 2 2 1 Interferon-related protein conserved region HEAT_2 PF13646.6 EGF82079.1 - 0.01 16.2 0.2 0.71 10.3 0.2 2.5 1 1 0 1 1 1 0 HEAT repeats TetR_C_24 PF17932.1 EGF82079.1 - 0.027 14.7 1.1 0.55 10.5 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain eIF3_subunit PF08597.10 EGF82081.1 - 1.8e-59 201.6 11.2 2e-59 201.4 11.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4887 PF16228.5 EGF82081.1 - 0.68 10.1 12.8 0.26 11.5 7.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) Ribosomal_S6 PF01250.17 EGF82081.1 - 0.89 9.9 3.3 2.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S6 UPF0061 PF02696.14 EGF82082.1 - 6.5e-107 358.2 0.0 1.3e-106 357.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Beta-lactamase PF00144.24 EGF82083.1 - 4.7e-39 134.5 0.0 7.5e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase MscL PF01741.18 EGF82084.1 - 8.4e-23 81.0 0.0 1.2e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_2 PF03107.16 EGF82084.1 - 7.9e-05 22.9 0.3 0.00013 22.2 0.3 1.3 1 0 0 1 1 1 1 C1 domain zinc_ribbon_15 PF17032.5 EGF82084.1 - 0.0024 18.6 0.2 0.0039 17.9 0.2 1.4 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 EGF82084.1 - 0.01 15.9 1.4 0.017 15.2 1.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon EphA2_TM PF14575.6 EGF82084.1 - 0.016 16.0 0.0 0.029 15.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Zn_ribbon_SprT PF17283.2 EGF82084.1 - 0.023 14.6 0.8 0.043 13.7 0.8 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain LapA_dom PF06305.11 EGF82084.1 - 0.033 14.0 0.5 0.033 14.0 0.5 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3169 PF11368.8 EGF82084.1 - 0.038 13.5 0.2 0.066 12.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) zinc_ribbon_2 PF13240.6 EGF82084.1 - 0.048 13.4 0.4 0.076 12.7 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 EGF82084.1 - 0.057 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HIT PF04438.16 EGF82084.1 - 0.065 13.1 1.3 0.094 12.6 1.3 1.2 1 0 0 1 1 1 0 HIT zinc finger CcmD PF04995.14 EGF82084.1 - 0.1 12.7 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) zf-CHY PF05495.12 EGF82084.1 - 0.17 12.4 1.6 0.26 11.8 1.6 1.2 1 0 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.12 EGF82084.1 - 0.21 11.6 2.0 0.34 10.9 2.0 1.2 1 0 0 1 1 1 0 zinc-ribbons Pkr1 PF08636.10 EGF82085.1 - 1.1e-20 73.6 8.7 1.1e-20 73.5 8.7 1.0 1 0 0 1 1 1 1 ER protein Pkr1 RNA_pol_Rpb1_1 PF04997.12 EGF82086.1 - 8e-112 373.6 0.1 1.3e-111 372.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGF82086.1 - 3.2e-104 348.1 0.1 4.8e-104 347.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGF82086.1 - 1.2e-76 256.5 0.0 2.3e-76 255.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGF82086.1 - 2.4e-69 233.0 1.2 5.3e-69 231.9 1.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGF82086.1 - 2.7e-48 163.9 0.3 2.4e-47 160.8 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGF82086.1 - 2.8e-38 131.0 0.5 7.4e-38 129.6 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGF82086.1 - 4.2e-38 129.6 0.2 1.1e-37 128.3 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGF82086.1 - 1.3e-09 37.9 388.9 0.33 11.4 15.9 18.4 10 2 2 18 18 18 13 RNA polymerase Rpb1 C-terminal repeat Dynamin_M PF01031.20 EGF82086.1 - 0.0051 16.1 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region zf-C4pol PF14260.6 EGF82086.1 - 0.59 10.6 2.8 1.5 9.3 2.8 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta LCM PF04072.14 EGF82087.1 - 1.2e-20 74.3 0.0 2.4e-19 70.0 0.0 2.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DHHC PF01529.20 EGF82088.1 - 4e-24 85.2 14.7 4e-24 85.2 14.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3347 PF11827.8 EGF82090.1 - 0.26 11.5 0.7 0.65 10.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Ribosomal_S21e PF01249.18 EGF82091.1 - 2.8e-34 117.1 0.0 3e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e PIG-S PF10510.9 EGF82092.1 - 0.01 14.7 4.3 0.012 14.5 4.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF1856 PF08983.10 EGF82092.1 - 0.048 13.9 0.2 0.048 13.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) Peptidase_A17 PF05380.13 EGF82092.1 - 0.096 12.7 1.7 0.14 12.1 1.5 1.4 1 1 0 1 1 1 0 Pao retrotransposon peptidase CEL_III_C PF18054.1 EGF82092.1 - 0.84 9.7 5.5 1.6 8.7 1.0 2.3 2 0 0 2 2 2 0 CEL-III C-terminal Steroid_dh PF02544.16 EGF82093.1 - 3.7e-15 56.2 6.7 3.7e-15 56.2 6.7 2.8 2 2 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase Methyltransf_16 PF10294.9 EGF82094.1 - 1.9e-09 37.5 0.1 3.3e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGF82094.1 - 1.5e-06 28.1 0.2 6.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF82094.1 - 0.00036 20.4 0.0 0.00058 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF82094.1 - 0.00079 20.1 0.0 0.16 12.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF82094.1 - 0.0021 18.8 0.0 0.0092 16.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF82094.1 - 0.004 17.8 0.0 0.071 13.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGF82094.1 - 0.076 12.4 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB PrmA PF06325.13 EGF82094.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ERCC4 PF02732.15 EGF82095.1 - 1.5e-10 41.5 0.1 1.5e-10 41.5 0.1 2.1 3 0 0 3 3 3 1 ERCC4 domain Sulfotransfer_4 PF17784.1 EGF82095.1 - 0.018 14.8 0.2 0.2 11.5 0.0 2.7 3 0 0 3 3 3 0 Sulfotransferase domain CUE PF02845.16 EGF82095.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 CUE domain Peptidase_S49_N PF08496.10 EGF82095.1 - 9.4 6.3 8.9 26 4.8 8.9 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LapA_dom PF06305.11 EGF82096.1 - 0.061 13.1 0.3 0.061 13.1 0.3 1.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF599 PF04654.12 EGF82096.1 - 0.069 12.6 0.2 0.081 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 G0-G1_switch_2 PF15103.6 EGF82096.1 - 0.086 13.3 0.1 0.18 12.2 0.0 1.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4834 PF16118.5 EGF82096.1 - 0.15 13.1 0.1 0.32 12.0 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF202 PF02656.15 EGF82096.1 - 0.22 12.0 1.8 0.33 11.4 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Myb_DNA-bind_2 PF08914.11 EGF82097.1 - 4.4e-12 46.0 0.6 1e-11 44.8 0.6 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.8 EGF82097.1 - 3.3e-11 43.1 1.2 8e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.10 EGF82097.1 - 6.9e-05 23.4 6.9 0.0012 19.4 0.1 3.4 2 1 0 2 2 2 1 Rap1, DNA-binding BRCT_2 PF16589.5 EGF82097.1 - 0.00017 21.9 0.0 0.00045 20.6 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Phospholamban PF04272.14 EGF82097.1 - 0.027 13.9 0.3 0.073 12.5 0.3 1.7 1 0 0 1 1 1 0 Phospholamban ELMO_CED12 PF04727.13 EGF82098.1 - 1.5e-23 83.8 0.1 4.1e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EGF82098.1 - 1.5e-22 80.6 0.6 3.2e-22 79.5 0.6 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EGF82098.1 - 0.0012 18.8 0.0 0.019 14.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) HIG_1_N PF04588.13 EGF82099.1 - 7.1e-05 22.9 0.2 0.00015 21.9 0.2 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region VirB8 PF04335.13 EGF82099.1 - 0.062 13.1 0.4 0.64 9.8 0.0 2.4 2 1 0 2 2 2 0 VirB8 protein DNAJ_related PF12339.8 EGF82101.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA-J related protein DUF3421 PF11901.8 EGF82102.1 - 4.5e-35 120.1 3.3 5.7e-22 77.9 0.3 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) RXT2_N PF08595.11 EGF82102.1 - 0.71 9.9 6.1 0.41 10.7 1.6 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal G_path_suppress PF15991.5 EGF82102.1 - 5.3 7.1 26.3 8.6 6.4 26.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor PPR_2 PF13041.6 EGF82103.1 - 4.9e-42 141.9 4.6 9.5e-12 44.9 0.0 6.1 2 2 5 7 7 7 6 PPR repeat family PPR PF01535.20 EGF82103.1 - 9.4e-41 135.2 2.8 5.2e-07 29.5 0.0 7.6 8 0 0 8 8 8 7 PPR repeat PPR_3 PF13812.6 EGF82103.1 - 3.6e-36 123.0 4.3 6.7e-13 48.5 0.0 5.2 1 1 6 7 7 7 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF82103.1 - 7.5e-32 108.7 0.1 9.3e-08 31.6 0.0 6.5 7 0 0 7 7 7 5 PPR repeat PPR_long PF17177.4 EGF82103.1 - 2.5e-19 69.5 0.0 2e-16 60.0 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Vps39_1 PF10366.9 EGF82103.1 - 4.8e-05 23.6 0.0 0.14 12.4 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_19 PF14559.6 EGF82103.1 - 0.00016 22.1 0.3 12 6.5 0.0 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat PET122 PF05476.11 EGF82103.1 - 0.00079 18.8 0.6 0.011 15.0 0.1 2.3 2 0 0 2 2 2 1 PET122 TPR_15 PF13429.6 EGF82103.1 - 0.0011 18.3 0.0 0.023 13.9 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82103.1 - 0.0013 19.3 0.0 3 8.9 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat ECSIT PF06239.11 EGF82103.1 - 0.0028 16.8 1.2 3.3 6.8 0.1 4.0 2 1 1 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway MRP-S27 PF10037.9 EGF82103.1 - 0.0044 16.0 0.4 0.014 14.3 0.4 1.7 1 1 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Clathrin PF00637.20 EGF82103.1 - 0.13 12.2 0.0 5.1 7.0 0.0 2.6 1 1 2 3 3 3 0 Region in Clathrin and VPS PYRIN PF02758.16 EGF82103.1 - 0.15 12.2 0.1 7 6.9 0.0 2.6 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain MNE1 PF13762.6 EGF82103.1 - 0.17 11.9 3.7 4.4 7.3 0.3 3.4 2 1 2 4 4 4 0 Mitochondrial splicing apparatus component DUF1992 PF09350.10 EGF82104.1 - 0.18 12.0 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) SAS-6_N PF16531.5 EGF82105.1 - 0.46 11.1 6.4 2.9 8.5 0.2 3.6 3 1 0 3 3 3 0 Centriolar protein SAS N-terminal cNMP_binding PF00027.29 EGF82106.1 - 1.4e-14 53.9 0.1 7.9e-12 45.1 0.0 3.3 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain BAR PF03114.18 EGF82107.1 - 2.8e-31 109.0 3.3 3.7e-31 108.6 3.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGF82107.1 - 4.3e-13 48.6 0.2 2.6e-12 46.1 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGF82107.1 - 1.9e-10 40.4 0.2 4.5e-10 39.2 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGF82107.1 - 1.4e-05 24.6 0.0 6.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Jnk-SapK_ap_N PF09744.9 EGF82107.1 - 0.66 10.2 3.8 0.88 9.8 0.4 2.4 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 ABC_tran PF00005.27 EGF82108.1 - 3.9e-28 98.7 0.0 9.6e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGF82108.1 - 6.7e-16 58.3 40.6 1.6e-14 53.8 41.6 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGF82108.1 - 1.2e-13 51.6 0.5 3.9e-10 40.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGF82108.1 - 0.0008 19.2 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EGF82108.1 - 0.00082 19.9 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGF82108.1 - 0.0021 17.5 0.1 0.21 11.0 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGF82108.1 - 0.0034 17.3 0.1 0.0085 16.0 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF82108.1 - 0.0044 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 EGF82108.1 - 0.089 11.4 0.0 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 EGF82108.1 - 0.1 11.4 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 EGF82108.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane PF01061.24 EGF82108.1 - 0.72 9.2 33.6 0.46 9.9 0.3 2.7 2 1 0 2 2 2 0 ABC-2 type transporter zf-RING_2 PF13639.6 EGF82109.1 - 1.6e-09 37.9 9.4 3.9e-09 36.7 9.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGF82109.1 - 7e-06 26.2 7.0 1.8e-05 24.9 7.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF82109.1 - 9.4e-06 25.4 8.0 2.1e-05 24.3 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF82109.1 - 5.5e-05 22.9 8.4 0.00012 21.8 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF82109.1 - 0.00021 21.0 7.5 0.00048 19.8 7.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGF82109.1 - 0.001 19.1 2.8 0.0043 17.1 2.8 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGF82109.1 - 0.0046 16.9 7.8 0.0087 16.0 7.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGF82109.1 - 0.029 14.2 5.2 0.052 13.4 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF82109.1 - 0.047 13.7 3.6 0.061 13.4 1.7 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGF82109.1 - 0.35 10.5 6.5 0.72 9.5 6.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGF82109.1 - 2.3 8.5 7.7 12 6.2 7.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EGF82109.1 - 2.4 8.4 9.0 5.3 7.3 9.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EGF82109.1 - 6.2 7.2 7.0 16 5.9 7.0 1.8 1 0 0 1 1 1 0 RING-like domain AICARFT_IMPCHas PF01808.18 EGF82110.1 - 6.2e-89 298.3 0.0 8.8e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGF82110.1 - 3.3e-23 81.7 0.0 9.4e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain Chorion_2 PF03964.15 EGF82113.1 - 0.12 13.3 0.1 0.52 11.2 0.2 1.9 2 0 0 2 2 2 0 Chorion family 2 DUF4269 PF14091.6 EGF82115.1 - 0.15 12.3 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) BTB_3 PF16017.5 EGF82116.1 - 0.02 15.0 0.1 0.044 13.9 0.1 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF82116.1 - 0.023 15.1 0.4 0.023 15.1 0.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3888) DUF3128 PF11326.8 EGF82117.1 - 1.8e-20 73.1 1.8 2.1e-20 72.8 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Syja_N PF02383.18 EGF82118.1 - 4.4e-68 230.0 0.0 7.5e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EGF82118.1 - 1.3e-07 31.4 0.0 3.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin_7 PF13899.6 EGF82120.1 - 3.2e-12 46.4 0.0 6.8e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 EGF82120.1 - 1.5e-09 37.9 0.2 3.3e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGF82120.1 - 2.3e-08 33.7 0.4 4.7e-08 32.7 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 EGF82120.1 - 0.05 13.5 0.2 0.099 12.6 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredoxin_2 PF13098.6 EGF82120.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Gluconate_2-dh3 PF13618.6 EGF82120.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 PGM_PMM_I PF02878.16 EGF82121.1 - 1.6e-34 118.6 0.2 3e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGF82121.1 - 4.9e-29 100.8 0.0 1e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGF82121.1 - 6.6e-19 68.4 0.0 1.6e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGF82121.1 - 3.7e-06 27.0 0.0 9.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glycos_transf_3 PF00591.21 EGF82122.1 - 3.9e-90 301.9 2.4 5.1e-90 301.5 2.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGF82122.1 - 4e-08 33.0 0.1 1e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Pkinase PF00069.25 EGF82123.1 - 7.3e-62 209.1 0.0 8.7e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82123.1 - 1.2e-46 159.1 0.0 1.5e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF82123.1 - 0.00045 19.1 0.0 0.00077 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF82123.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF82123.1 - 0.019 13.9 0.1 2.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain SIS PF01380.22 EGF82124.1 - 1e-66 222.7 0.2 1.1e-34 119.1 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGF82124.1 - 4.6e-18 65.7 0.0 1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGF82124.1 - 3.1e-14 52.9 0.0 6.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGF82124.1 - 9.4e-05 21.4 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Mgm101p PF06420.12 EGF82125.1 - 1.6e-51 174.2 0.0 1.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Pcc1 PF09341.10 EGF82126.1 - 7.2e-19 67.7 0.9 1e-18 67.2 0.9 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 YGGT PF02325.17 EGF82126.1 - 0.11 13.0 0.4 0.79 10.2 0.0 2.0 1 1 1 2 2 2 0 YGGT family Longin PF13774.6 EGF82127.1 - 6.6e-26 90.2 0.1 1.1e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGF82127.1 - 1.1e-14 54.0 0.0 2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin iPGM_N PF06415.13 EGF82127.1 - 0.0058 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) ArnB_C PF18677.1 EGF82127.1 - 0.054 13.6 0.2 0.15 12.2 0.2 1.8 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain DUF1279 PF06916.13 EGF82127.1 - 0.16 12.5 0.6 13 6.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) DUF240 PF03086.14 EGF82127.1 - 0.51 10.3 3.2 0.23 11.4 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF240) tRNA_U5-meth_tr PF05958.11 EGF82128.1 - 8e-06 25.1 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EGF82128.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PHP PF02811.19 EGF82129.1 - 1e-16 61.7 0.5 2.1e-16 60.7 0.5 1.5 1 1 0 1 1 1 1 PHP domain TACC_C PF05010.14 EGF82130.1 - 6.4e-54 182.8 36.5 6.4e-54 182.8 36.5 1.7 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 EGF82130.1 - 0.00065 19.4 29.5 0.00065 19.4 29.5 2.7 2 1 1 3 3 3 2 Intermediate filament protein zf-rbx1 PF12678.7 EGF82131.1 - 3.2e-25 88.2 12.5 5.9e-25 87.3 12.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGF82131.1 - 4e-17 62.1 10.6 6.4e-17 61.4 10.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGF82131.1 - 0.0001 22.6 20.0 0.00017 21.8 15.1 2.7 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF82131.1 - 0.0029 17.4 14.6 0.0054 16.6 9.3 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF82131.1 - 0.024 14.5 11.5 0.024 14.5 11.5 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGF82131.1 - 0.096 12.9 8.3 0.6 10.3 8.6 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 EGF82131.1 - 0.46 10.6 7.8 2 8.5 7.8 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 EGF82131.1 - 0.87 9.4 16.9 94 2.9 16.9 2.7 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGF82131.1 - 2.3 8.1 14.2 0.48 10.3 4.2 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGF82131.1 - 5.6 6.7 19.3 0.096 12.3 5.3 2.7 2 1 1 3 3 3 0 Zinc-ribbon, C4HC2 type XRN_N PF03159.18 EGF82132.1 - 4.3e-21 75.4 0.0 1.4e-20 73.8 0.0 1.8 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF4097 PF13349.6 EGF82132.1 - 7.8e-05 22.1 0.9 0.0003 20.2 0.7 1.9 1 1 1 2 2 2 1 Putative adhesin Sigma70_ner PF04546.13 EGF82133.1 - 0.0049 16.8 1.5 0.0049 16.8 1.5 1.7 2 1 0 2 2 2 1 Sigma-70, non-essential region CENP-I PF07778.11 EGF82133.1 - 0.045 12.5 1.8 0.06 12.1 1.8 1.2 1 0 0 1 1 1 0 Mis6 FAM176 PF14851.6 EGF82133.1 - 0.34 10.5 5.7 0.055 13.1 0.8 2.0 2 0 0 2 2 2 0 FAM176 family GCIP PF13324.6 EGF82133.1 - 3 7.4 8.8 0.47 10.0 4.8 1.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting IBN_N PF03810.19 EGF82134.1 - 0.00018 21.4 0.9 0.00043 20.2 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain AIRC PF00731.20 EGF82135.1 - 1.6e-63 212.7 3.2 3.5e-63 211.6 1.5 2.2 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 EGF82135.1 - 1.3e-54 184.4 0.0 2.1e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGF82135.1 - 8.9e-19 66.9 0.0 1.8e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EGF82135.1 - 6.3e-08 32.4 0.0 1.8e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EGF82135.1 - 0.001 18.7 0.0 0.0062 16.1 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 EGF82135.1 - 0.011 15.3 0.3 0.031 13.8 0.0 1.9 2 0 0 2 2 2 0 Propionate catabolism activator 2-Hacid_dh_C PF02826.19 EGF82135.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CCDC24 PF15669.5 EGF82136.1 - 5.2e-07 29.8 5.2 0.0058 16.5 0.1 2.8 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 24 family MutL_C PF08676.11 EGF82136.1 - 0.35 10.6 2.2 34 4.2 0.1 3.1 3 0 0 3 3 3 0 MutL C terminal dimerisation domain ERG4_ERG24 PF01222.17 EGF82138.1 - 2.4e-142 474.7 10.4 2.7e-142 474.5 10.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family APH PF01636.23 EGF82140.1 - 3.7e-37 128.5 0.0 4.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGF82140.1 - 1.6e-05 24.4 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EGF82140.1 - 3.5e-05 23.5 0.0 5.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HhH-GPD PF00730.25 EGF82140.1 - 0.17 12.4 0.0 0.4 11.2 0.0 1.5 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein CLU PF13236.6 EGF82141.1 - 4.9e-80 268.5 0.1 9.2e-80 267.6 0.1 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGF82141.1 - 1.3e-36 126.2 0.2 4.6e-36 124.5 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGF82141.1 - 2.1e-15 56.7 1.7 0.00026 21.2 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.6 EGF82141.1 - 2.7e-12 46.9 1.4 4.9e-12 46.0 0.3 2.1 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EGF82141.1 - 1.6e-08 34.1 0.3 0.4 10.6 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF727 PF05303.12 EGF82141.1 - 2.8e-05 24.1 0.0 0.00011 22.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_7 PF13176.6 EGF82141.1 - 0.023 14.7 0.1 0.34 11.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82141.1 - 0.031 14.4 0.8 21 5.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82141.1 - 0.08 13.2 0.2 3.1 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_22 PF13309.6 EGF82143.1 - 0.1 12.7 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 HTH domain THOC7 PF05615.13 EGF82143.1 - 0.47 10.7 6.9 0.21 11.9 3.5 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DDHD PF02862.17 EGF82144.1 - 1.5e-55 188.8 0.0 5.5e-54 183.7 0.0 2.2 2 0 0 2 2 2 1 DDHD domain Lipase_3 PF01764.25 EGF82144.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF167 PF02594.16 EGF82145.1 - 1.8e-20 72.8 1.6 3e-20 72.1 1.6 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Aminopep PF10023.9 EGF82146.1 - 0.051 12.9 1.4 0.059 12.7 1.4 1.2 1 0 0 1 1 1 0 Putative aminopeptidase DUF1682 PF07946.14 EGF82146.1 - 0.072 12.3 4.6 0.087 12.0 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UBN_AB PF14075.6 EGF82146.1 - 0.073 12.8 4.5 0.088 12.5 4.5 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Ntox1 PF15500.6 EGF82146.1 - 0.24 11.8 3.0 0.16 12.4 1.1 1.7 2 1 0 2 2 2 0 Putative RNase-like toxin, toxin_1 MBOAT PF03062.19 EGF82147.1 - 7.2e-21 74.9 16.2 7.6e-21 74.8 15.3 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGF82147.1 - 0.0006 20.0 1.1 0.0006 20.0 1.1 2.8 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Ninjurin PF04923.12 EGF82147.1 - 0.18 11.7 5.4 0.07 13.1 0.8 2.6 3 0 0 3 3 3 0 Ninjurin ABC_tran PF00005.27 EGF82149.1 - 1.4e-48 164.8 0.0 3.8e-25 89.0 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGF82149.1 - 9.8e-17 61.7 0.3 0.00059 19.7 0.1 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGF82149.1 - 2e-13 50.3 0.2 0.0067 15.9 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EGF82149.1 - 1.5e-09 37.6 0.1 3.4e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EGF82149.1 - 1.2e-07 32.5 0.4 0.0067 16.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EGF82149.1 - 2.5e-07 30.4 0.3 0.033 13.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGF82149.1 - 1.9e-05 24.6 0.2 0.075 12.9 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EGF82149.1 - 6.7e-05 22.9 0.1 0.058 13.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EGF82149.1 - 0.00011 22.7 0.0 0.35 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGF82149.1 - 0.00022 21.5 0.0 0.44 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGF82149.1 - 0.00041 20.5 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 EGF82149.1 - 0.00068 19.3 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGF82149.1 - 0.00092 19.5 0.0 0.65 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Vac14_Fab1_bd PF12755.7 EGF82149.1 - 0.0012 19.3 0.0 1.8 9.2 0.0 2.7 1 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGF82149.1 - 0.0014 19.0 3.3 0.22 12.0 0.0 3.7 2 1 2 4 4 4 2 HEAT repeats AAA_16 PF13191.6 EGF82149.1 - 0.0022 18.4 0.2 2.2 8.7 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_15 PF13175.6 EGF82149.1 - 0.0022 17.8 0.5 2.2 7.9 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain MeaB PF03308.16 EGF82149.1 - 0.0024 16.9 0.8 0.52 9.2 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 EGF82149.1 - 0.0026 17.7 0.0 0.81 9.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 EGF82149.1 - 0.0043 17.4 0.1 5 7.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 EGF82149.1 - 0.0045 16.7 2.8 0.66 9.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 EGF82149.1 - 0.0059 16.5 0.2 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EGF82149.1 - 0.014 15.5 0.3 0.3 11.1 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 EGF82149.1 - 0.014 15.8 0.1 9.7 6.6 0.0 3.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGF82149.1 - 0.015 15.0 0.5 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGF82149.1 - 0.04 13.4 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EGF82149.1 - 0.053 13.7 0.1 4.4 7.6 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MutS_V PF00488.21 EGF82149.1 - 0.1 12.6 0.7 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 MutS domain V ATP_bind_1 PF03029.17 EGF82149.1 - 0.1 12.4 0.4 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3584 PF12128.8 EGF82149.1 - 0.2 9.1 0.3 2.4 5.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Roc PF08477.13 EGF82149.1 - 0.21 11.8 1.0 37 4.5 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Adaptin_N PF01602.20 EGF82149.1 - 0.32 9.5 1.5 2.9 6.3 1.4 2.1 1 1 0 1 1 1 0 Adaptin N terminal region cobW PF02492.19 EGF82149.1 - 0.43 10.2 2.4 15 5.1 0.0 3.0 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EGF82149.1 - 0.49 10.4 2.8 1.5 8.9 0.0 3.0 4 0 0 4 4 3 0 Dynamin family HEAT PF02985.22 EGF82149.1 - 0.79 10.1 4.5 23 5.6 0.1 4.1 4 0 0 4 4 2 0 HEAT repeat HEAT_EZ PF13513.6 EGF82149.1 - 3.7 8.1 8.5 1.5e+02 3.0 0.1 5.0 4 1 1 5 5 5 0 HEAT-like repeat Adaptin_N PF01602.20 EGF82151.1 - 2.4e-106 356.4 10.4 3.1e-106 356.0 10.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGF82151.1 - 9.4e-17 61.5 4.4 6.6e-11 42.5 0.1 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF82151.1 - 1.3e-10 41.5 0.3 0.00013 22.3 0.0 3.2 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EGF82151.1 - 3e-09 36.4 1.0 0.12 12.7 0.1 5.8 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 EGF82151.1 - 8.5e-05 22.7 2.4 0.012 15.8 0.0 3.4 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGF82151.1 - 0.00016 22.1 6.7 0.68 10.5 0.0 6.6 6 1 2 8 8 7 2 HEAT-like repeat Proteasom_PSMB PF10508.9 EGF82151.1 - 0.00036 19.2 1.8 0.11 10.9 0.4 2.9 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit MA3 PF02847.17 EGF82151.1 - 0.0004 20.3 1.9 0.0066 16.4 0.0 3.3 3 0 0 3 3 3 1 MA3 domain Arm PF00514.23 EGF82151.1 - 0.00076 19.4 2.6 8.7 6.6 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 EGF82151.1 - 0.012 15.9 1.6 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.6 EGF82151.1 - 0.057 13.8 2.2 4.6 7.7 0.0 3.7 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SRP54_N PF02881.19 EGF82151.1 - 0.075 13.3 0.6 0.41 10.9 0.3 2.4 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain V-ATPase_H_C PF11698.8 EGF82151.1 - 0.094 12.8 1.2 13 5.9 0.1 4.2 4 1 0 4 4 3 0 V-ATPase subunit H Myb_DNA-binding PF00249.31 EGF82153.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-B_box PF00643.24 EGF82154.1 - 1.5e-14 53.8 13.6 1.7e-07 31.3 3.9 2.3 2 0 0 2 2 2 2 B-box zinc finger DUF29 PF01724.16 EGF82154.1 - 0.072 13.3 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 Muted PF14942.6 EGF82154.1 - 1.4 9.3 5.5 2.6 8.4 1.6 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Y_phosphatase PF00102.27 EGF82155.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGF82155.1 - 0.00034 20.4 0.0 0.00097 19.0 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGF82155.1 - 0.12 12.0 0.1 0.5 10.0 0.1 1.9 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-RING_2 PF13639.6 EGF82156.1 - 1.6e-11 44.3 9.5 1.6e-11 44.3 9.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 EGF82156.1 - 6.5e-09 35.4 2.5 6.5e-09 35.4 2.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF82156.1 - 1.1e-07 31.7 3.9 2.6e-07 30.4 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF82156.1 - 4.7e-07 29.5 9.5 4.7e-07 29.5 9.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF82156.1 - 0.0011 19.3 12.3 0.0081 16.4 12.3 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGF82156.1 - 0.0018 18.1 4.6 0.0018 18.1 4.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF82156.1 - 0.0024 17.8 5.5 0.0033 17.4 1.2 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF82156.1 - 0.0073 16.1 6.4 0.018 14.9 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF82156.1 - 0.015 15.2 6.2 0.015 15.2 6.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain PA PF02225.22 EGF82156.1 - 0.022 14.7 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 PA domain zf-ANAPC11 PF12861.7 EGF82156.1 - 0.051 13.6 4.0 0.18 11.9 4.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGF82156.1 - 1.7 8.3 5.7 5.3 6.8 5.7 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SWIRM PF04433.17 EGF82157.1 - 1.7e-06 28.3 0.0 3.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Spc24 PF08286.11 EGF82158.1 - 8.3e-22 77.4 9.0 1.2e-21 76.9 2.1 2.3 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 MIP-T3_C PF17749.1 EGF82158.1 - 0.15 12.0 6.2 0.6 10.1 6.1 2.0 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region YlqD PF11068.8 EGF82158.1 - 1.3 9.4 12.2 0.38 11.1 8.6 1.8 1 1 1 2 2 2 0 YlqD protein FUSC PF04632.12 EGF82158.1 - 3.6 6.0 6.9 4.3 5.7 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Efg1 PF10153.9 EGF82158.1 - 3.9 7.9 7.7 8.4 6.8 7.7 1.8 1 1 0 1 1 1 0 rRNA-processing protein Efg1 RNA_pol_Rpb4 PF03874.16 EGF82159.1 - 3.8e-22 78.9 1.3 5.3e-22 78.4 1.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 GSH_synth_ATP PF03917.17 EGF82161.1 - 1.8e-124 415.3 0.0 2.1e-124 415.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGF82161.1 - 1e-32 112.6 0.0 2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Peptidase_S41 PF03572.18 EGF82162.1 - 1.3e-14 54.1 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 GN3L_Grn1 PF08701.11 EGF82163.1 - 4.9e-22 77.8 7.5 4.9e-22 77.8 7.5 2.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EGF82163.1 - 2.4e-17 63.0 0.1 3.3e-13 49.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF82163.1 - 1.8e-09 37.3 0.2 2.2e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF82163.1 - 2.5e-07 30.8 0.3 0.011 15.7 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGF82163.1 - 2.9e-05 23.7 0.1 0.0018 17.8 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGF82163.1 - 0.0032 16.8 0.3 0.01 15.2 0.1 1.9 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EGF82163.1 - 0.099 13.0 0.2 1.2 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EGF82163.1 - 0.19 11.8 11.6 0.56 10.2 0.7 4.3 3 2 1 4 4 4 0 Dynamin family MbeB_N PF04837.12 EGF82163.1 - 6.2 7.2 7.0 0.86 10.0 1.7 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region BHD_3 PF10405.9 EGF82164.1 - 1.3e-26 92.8 0.0 3.2e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EGF82164.1 - 1.7e-17 63.0 0.0 3.5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 EGF82164.1 - 3.4e-16 59.3 1.1 7.9e-16 58.1 1.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 EGF82164.1 - 5.6e-10 40.0 0.0 1.3e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EGF82164.1 - 0.017 15.6 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily HEAT_EZ PF13513.6 EGF82165.1 - 2.2e-19 69.5 11.9 1.8e-05 25.1 0.6 8.7 8 3 2 10 10 10 4 HEAT-like repeat HEAT PF02985.22 EGF82165.1 - 2.4e-15 55.3 20.8 0.0023 18.0 0.1 11.7 13 0 0 13 13 13 3 HEAT repeat HEAT_2 PF13646.6 EGF82165.1 - 2.2e-12 47.2 4.1 0.00026 21.3 0.2 6.9 6 1 0 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF82165.1 - 5.9e-12 46.0 2.8 0.0051 17.4 0.0 7.1 5 2 2 7 7 7 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EGF82165.1 - 2.1e-07 30.7 0.5 2.8e-06 27.1 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 EGF82165.1 - 3.3e-07 30.2 0.1 2.3 7.9 0.0 5.5 3 2 1 5 5 5 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 EGF82165.1 - 1.3e-06 27.3 1.5 0.00013 20.7 0.2 2.8 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 EGF82165.1 - 2.9e-06 27.4 3.3 0.0027 17.8 0.2 4.2 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EGF82165.1 - 7.6e-05 22.7 2.4 0.53 10.2 0.1 6.2 6 1 2 8 8 8 2 Domain of unknown function (DUF3385) RTP1_C1 PF10363.9 EGF82165.1 - 0.00015 21.9 0.3 8 6.7 0.1 4.9 3 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 EGF82165.1 - 0.00053 19.2 6.9 0.21 10.6 3.1 5.1 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 EGF82165.1 - 0.17 11.4 1.1 20 4.6 0.6 3.4 3 1 1 4 4 4 0 Tti2 family Sec62 PF03839.16 EGF82166.1 - 4.1e-47 160.5 3.6 1.5e-46 158.6 3.6 1.8 1 1 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 EGF82166.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNRNP27 PF08648.12 EGF82167.1 - 7.5e-26 90.0 0.6 7.5e-26 90.0 0.6 2.4 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Lpp-LpqN PF10738.9 EGF82168.1 - 0.035 13.6 0.0 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 Probable lipoprotein LpqN ZirS_C PF16583.5 EGF82168.1 - 0.053 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Rep_fac-A_3 PF08661.11 EGF82169.1 - 2.2e-15 56.9 0.2 2.5e-15 56.7 0.2 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 DUF1861 PF08950.10 EGF82169.1 - 0.07 12.4 0.0 0.074 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1861) WD40 PF00400.32 EGF82170.1 - 4.9e-27 93.7 20.2 4.4e-07 30.5 0.4 7.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82170.1 - 5.1e-06 26.7 0.1 2.1 8.7 0.0 4.9 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF82170.1 - 5.5e-05 22.6 0.1 0.091 12.1 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EGF82170.1 - 0.001 18.1 0.2 0.26 10.2 0.0 2.6 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGF82170.1 - 0.0029 17.5 1.2 0.46 10.3 0.3 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CLU_N PF15044.6 EGF82170.1 - 0.041 14.3 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Sdh_cyt PF01127.22 EGF82171.1 - 6.6e-20 71.3 5.9 9.3e-20 70.9 5.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NTP_transf_2 PF01909.23 EGF82172.1 - 1.1e-12 48.1 0.1 2.3e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGF82172.1 - 5.1e-06 26.6 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGF82172.1 - 0.0013 18.8 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DHR-2 PF06920.13 EGF82173.1 - 9.7e-71 239.0 8.1 1e-38 133.3 1.6 3.8 3 1 0 3 3 3 3 Dock homology region 2 DOCK_N PF16172.5 EGF82173.1 - 3.8e-47 161.0 0.0 7.4e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EGF82173.1 - 5.3e-37 127.5 0.0 1.6e-36 126.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins bZIP_1 PF00170.21 EGF82174.1 - 1.3e-08 34.8 6.8 1.3e-08 34.8 6.8 2.4 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EGF82174.1 - 9.9e-06 25.6 8.4 9.9e-06 25.6 8.4 3.4 3 0 0 3 3 3 1 Basic region leucine zipper Lectin_N PF03954.14 EGF82174.1 - 0.034 13.9 0.2 0.16 11.7 0.2 2.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 EGF82174.1 - 0.042 12.9 10.6 0.093 11.8 10.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 EGF82174.1 - 0.26 11.5 4.2 0.25 11.5 0.4 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TMCO5 PF14992.6 EGF82174.1 - 6.3 6.3 10.2 0.55 9.8 2.4 2.4 3 0 0 3 3 3 0 TMCO5 family Ribosomal_L17 PF01196.19 EGF82175.1 - 9e-23 81.0 0.1 2e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 GGACT PF06094.12 EGF82175.1 - 0.15 12.6 0.1 0.81 10.3 0.0 2.1 2 0 0 2 2 2 0 Gamma-glutamyl cyclotransferase, AIG2-like Abhydrolase_1 PF00561.20 EGF82176.1 - 5.4e-18 65.6 0.1 1.2e-17 64.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EGF82176.1 - 1.8e-17 62.7 0.0 4.8e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EGF82176.1 - 0.0003 20.1 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIM PF00412.22 EGF82177.1 - 3.6e-46 155.2 41.0 1.8e-14 53.7 4.8 4.0 4 0 0 4 4 4 4 LIM domain zf-ribbon_3 PF13248.6 EGF82177.1 - 0.15 11.5 0.0 0.15 11.5 0.0 5.5 6 0 0 6 6 6 0 zinc-ribbon domain zf_UBZ PF18439.1 EGF82177.1 - 0.19 11.3 0.1 0.19 11.3 0.1 4.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DUF2685 PF10886.8 EGF82177.1 - 4.2 7.6 0.0 4.2 7.6 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2685) zf-C3HC4_3 PF13920.6 EGF82177.1 - 9.3 6.2 34.4 7.8 6.4 0.1 6.7 5 2 1 6 6 6 0 Zinc finger, C3HC4 type (RING finger) RCC1 PF00415.18 EGF82179.1 - 2.4e-47 159.3 24.0 3.7e-09 37.1 0.1 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGF82179.1 - 5.2e-23 80.3 48.8 1.4e-06 27.9 0.5 8.1 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Haspin_kinase PF12330.8 EGF82180.1 - 1.6e-52 178.7 7.3 2.1e-52 178.3 7.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 EGF82180.1 - 1.3e-06 28.0 0.5 1.4e-05 24.7 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82180.1 - 0.00071 18.9 1.8 0.003 16.9 0.3 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGF82180.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EGF82180.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2367 PF10164.9 EGF82181.1 - 8e-10 39.2 3.4 1.3e-09 38.5 3.4 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) DUF4051 PF13260.6 EGF82181.1 - 0.073 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) CRM1_repeat_3 PF18787.1 EGF82181.1 - 0.98 9.6 0.0 0.98 9.6 0.0 2.0 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 Adaptin_N PF01602.20 EGF82182.1 - 3.8e-128 428.3 2.2 4.4e-128 428.1 2.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGF82182.1 - 1.2e-06 28.7 3.2 9.8e-05 22.5 0.1 3.8 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EGF82182.1 - 0.00029 20.8 3.6 1.7 8.8 0.0 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 EGF82182.1 - 0.022 15.3 0.4 2.9 8.5 0.0 3.5 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region DNA_alkylation PF08713.11 EGF82182.1 - 0.025 14.3 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 DNA alkylation repair enzyme CRAL_TRIO PF00650.20 EGF82183.1 - 1e-19 70.8 0.0 6e-19 68.3 0.0 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain GIT1_C PF12205.8 EGF82184.1 - 8.3e-05 22.7 0.1 0.00026 21.1 0.1 1.9 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term GIT_SHD PF08518.11 EGF82184.1 - 0.0014 18.2 0.2 0.28 10.9 0.0 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PUL PF08324.11 EGF82185.1 - 1.7e-09 37.3 0.0 2.8e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 EGF82186.1 - 1.3e-14 54.0 0.0 2.4e-14 53.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGF82186.1 - 3.7e-08 33.8 0.0 7.2e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGF82186.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGF82186.1 - 0.014 15.7 0.0 0.56 10.6 0.0 2.4 1 1 2 3 3 3 0 Thioredoxin-like Thioredoxin_4 PF13462.6 EGF82186.1 - 0.13 12.4 0.0 0.78 9.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin NIPSNAP PF07978.13 EGF82187.1 - 3e-41 139.8 3.6 3.3e-28 97.9 0.4 2.0 2 0 0 2 2 2 2 NIPSNAP PPR PF01535.20 EGF82188.1 - 3.6e-08 33.1 0.8 0.47 10.8 0.0 5.3 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 EGF82188.1 - 7.8e-06 26.0 2.9 3.2 8.0 0.0 5.3 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 EGF82188.1 - 0.019 15.0 2.3 3.1 8.0 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain ANAPC3 PF12895.7 EGF82188.1 - 0.19 12.0 3.6 6.9 7.0 0.9 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP13 PF12921.7 EGF82188.1 - 0.62 9.9 3.5 1.7 8.5 0.0 3.2 4 0 0 4 4 4 0 Mitochondrial ATPase expression COX17 PF05051.13 EGF82189.1 - 1.4e-20 73.3 8.0 1.8e-20 73.0 8.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) TMEM135_C_rich PF15982.5 EGF82190.1 - 8.3e-07 29.7 1.4 3.3e-06 27.7 0.5 1.9 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 UBM PF14377.6 EGF82191.1 - 0.0092 15.4 1.3 0.035 13.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin binding region WD40 PF00400.32 EGF82192.1 - 1.9e-14 53.8 9.4 0.0019 19.0 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82192.1 - 7e-05 23.1 0.1 17 5.8 0.0 6.1 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain zf-H2C2_2 PF13465.6 EGF82193.1 - 1.6e-14 53.6 20.0 1.5e-07 31.5 1.8 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF82193.1 - 5e-12 45.6 17.9 0.00062 20.4 1.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF82193.1 - 8.6e-12 44.8 18.4 0.00011 22.5 2.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGF82193.1 - 1e-06 28.6 12.7 0.00075 19.4 0.7 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF82193.1 - 3.8e-06 27.1 4.7 0.066 13.5 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF82193.1 - 6.7e-06 26.3 11.2 0.0056 17.0 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 EGF82193.1 - 0.00015 22.4 9.3 0.00039 21.1 1.0 2.8 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 EGF82193.1 - 0.003 17.3 18.0 0.022 14.5 1.1 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EGF82193.1 - 0.003 17.4 1.3 0.003 17.4 1.3 2.7 4 0 0 4 4 3 1 zinc-finger of a C2HC-type RNA_POL_M_15KD PF02150.16 EGF82193.1 - 0.039 13.8 1.7 9 6.3 0.0 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-CHY PF05495.12 EGF82193.1 - 0.067 13.7 8.1 1 9.9 0.3 2.5 1 1 0 2 2 2 0 CHY zinc finger zf-C2H2_2 PF12756.7 EGF82193.1 - 0.081 13.3 6.4 44 4.5 7.0 2.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) BolA PF01722.18 EGF82193.1 - 0.11 12.8 0.4 6.4 7.1 0.3 2.7 1 1 1 2 2 2 0 BolA-like protein CDC24_OB3 PF17244.2 EGF82193.1 - 0.13 12.0 3.5 0.13 12.0 3.5 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 zf-AN1 PF01428.16 EGF82193.1 - 0.15 12.2 13.1 3.5 7.9 2.5 3.2 2 1 1 3 3 3 0 AN1-like Zinc finger zf-C2HE PF16278.5 EGF82193.1 - 0.17 12.4 14.8 0.71 10.4 0.8 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger C1_1 PF00130.22 EGF82193.1 - 0.2 11.5 6.1 2.8 7.9 1.2 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_8 PF15909.5 EGF82193.1 - 0.32 11.3 8.8 0.64 10.3 4.0 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 EGF82193.1 - 0.35 11.0 4.4 57 3.9 3.0 3.0 2 1 1 3 3 3 0 Zinc ribbon domain DUF678 PF05077.12 EGF82193.1 - 0.39 10.9 4.3 0.61 10.3 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF678) Ta0938 PF11494.8 EGF82193.1 - 0.47 10.8 1.6 9.7 6.5 0.0 2.4 1 1 2 3 3 3 0 Ta0938 C1_4 PF07975.12 EGF82193.1 - 0.54 10.5 8.0 0.14 12.4 0.9 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf_ZIC PF18366.1 EGF82193.1 - 0.82 9.8 3.3 14 5.9 0.1 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain LIM PF00412.22 EGF82193.1 - 6.2 7.1 9.6 5.1 7.4 0.5 2.9 1 1 0 2 2 2 0 LIM domain bZIP_2 PF07716.15 EGF82194.1 - 3.2e-08 33.5 4.3 3.2e-08 33.5 4.3 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EGF82194.1 - 9.3e-08 32.1 3.1 2.4e-07 30.8 3.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 EGF82194.1 - 0.11 12.5 4.5 0.15 12.1 4.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-F_leu_zip PF10473.9 EGF82194.1 - 0.12 12.4 5.8 0.22 11.6 5.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_Maf PF03131.17 EGF82194.1 - 0.52 10.9 9.7 0.052 14.1 3.6 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor ATG16 PF08614.11 EGF82194.1 - 1.9 8.7 14.6 3.4 7.9 14.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 EGF82195.1 - 0.00019 21.4 13.2 0.00019 21.4 13.2 2.8 1 1 2 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EGF82195.1 - 0.00082 19.4 13.9 0.00082 19.4 13.9 2.2 1 1 2 3 3 3 2 bZIP transcription factor bZIP_Maf PF03131.17 EGF82195.1 - 7.5 7.1 17.2 2.2 8.8 10.4 3.0 1 1 1 2 2 2 0 bZIP Maf transcription factor RRM_1 PF00076.22 EGF82196.1 - 2.3e-20 72.2 0.0 3.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF82196.1 - 1.8e-06 28.0 0.0 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EGF82196.1 - 0.068 13.1 0.0 0.25 11.3 0.0 1.8 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Rota_VP2 PF05087.12 EGF82196.1 - 0.07 11.3 0.0 0.073 11.2 0.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF1314 PF07013.11 EGF82196.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) NPR2 PF06218.11 EGF82197.1 - 2.1e-116 389.3 13.4 9.5e-93 311.3 9.9 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 EGF82197.1 - 3.7e-05 22.7 4.3 0.0082 15.0 0.3 2.5 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Vinculin PF01044.19 EGF82198.1 - 9.1e-52 176.5 34.9 1.6e-26 92.9 10.7 2.5 2 1 0 2 2 2 2 Vinculin family PriC PF07445.12 EGF82198.1 - 0.29 11.1 6.9 0.32 10.9 1.2 2.8 2 0 0 2 2 2 0 Primosomal replication protein priC Glyco_hydro_67N PF03648.14 EGF82198.1 - 2 8.7 5.0 21 5.4 0.1 4.2 4 0 0 4 4 4 0 Glycosyl hydrolase family 67 N-terminus 2OG-FeII_Oxy_2 PF13532.6 EGF82201.1 - 8.8e-15 55.4 0.0 3.8e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UCH PF00443.29 EGF82202.1 - 1.5e-45 155.7 0.1 4.3e-45 154.2 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGF82202.1 - 1.4e-24 85.6 3.6 1.8e-23 82.1 0.5 2.7 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 EGF82202.1 - 3.2e-22 78.0 0.0 6.3e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 EGF82202.1 - 6.6e-22 77.6 20.1 1.9e-19 69.7 0.7 3.8 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGF82202.1 - 4.1e-19 69.3 5.5 2.8e-16 60.0 0.1 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-HC5HC2H_2 PF13832.6 EGF82203.1 - 2.9e-14 53.2 12.2 2.2e-13 50.3 6.4 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGF82203.1 - 7.2e-11 42.2 15.0 1.4e-09 38.1 4.3 3.2 2 1 1 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 EGF82203.1 - 7.9e-10 38.5 20.7 1.1e-07 31.6 7.8 2.8 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 EGF82203.1 - 2.2e-08 33.5 6.4 2.2e-08 33.5 6.4 2.5 2 0 0 2 2 2 1 PHD-finger Fib_alpha PF08702.10 EGF82203.1 - 0.0033 17.6 1.5 0.01 16.0 1.5 1.8 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 EGF82203.1 - 0.37 11.2 3.3 0.45 10.9 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4706 PF15797.5 EGF82203.1 - 0.46 11.0 2.6 0.5 10.9 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) NOA36 PF06524.12 EGF82203.1 - 8.2 5.7 27.2 0.6 9.4 21.4 2.1 2 0 0 2 2 2 0 NOA36 protein zf-RING-like PF08746.11 EGF82203.1 - 8.4 6.8 16.7 5.2 7.5 4.7 2.8 2 1 0 2 2 2 0 RING-like domain PIH1 PF08190.12 EGF82204.1 - 1.1e-08 34.7 0.4 2.6e-08 33.5 0.4 1.7 1 1 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGF82204.1 - 7e-05 23.2 0.1 0.00018 21.9 0.1 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain SGTA_dimer PF16546.5 EGF82204.1 - 0.033 14.0 0.1 0.085 12.6 0.1 1.7 1 0 0 1 1 1 0 Homodimerisation domain of SGTA WBS_methylT PF12589.8 EGF82205.1 - 4.9e-17 62.5 4.7 7.6e-17 61.8 4.7 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGF82205.1 - 4.2e-10 40.1 0.0 8.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF82205.1 - 1.4e-09 38.6 0.0 2.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF82205.1 - 1.7e-05 25.5 0.0 4.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF82205.1 - 2.3e-05 24.3 0.0 3.9e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF82205.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EGF82205.1 - 0.00092 19.5 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 EGF82205.1 - 0.0036 16.9 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 EGF82205.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGF82205.1 - 0.031 14.3 0.3 0.062 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 EGF82205.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.18 EGF82205.1 - 0.071 12.8 0.5 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 DNA methylase MTS PF05175.14 EGF82205.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TPR_11 PF13414.6 EGF82206.1 - 1.4e-06 27.9 0.9 8.6e-06 25.3 0.1 2.3 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 EGF82206.1 - 1.8e-05 24.8 0.4 0.0003 20.9 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82206.1 - 0.00014 21.5 2.3 0.022 14.6 1.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82206.1 - 0.00018 21.7 0.8 0.00078 19.7 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82206.1 - 0.00065 20.3 1.8 0.0065 17.2 0.0 3.2 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82206.1 - 0.00067 19.6 1.8 1.5 9.1 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82206.1 - 0.038 14.2 3.6 0.35 11.2 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82206.1 - 0.043 13.7 1.6 0.32 10.9 0.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Mur_ligase_M PF08245.12 EGF82207.1 - 0.0001 22.3 0.2 0.0028 17.7 0.0 2.8 2 1 1 3 3 3 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EGF82207.1 - 0.019 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Vps39_1 PF10366.9 EGF82208.1 - 8.3e-14 51.8 0.3 5.7e-13 49.1 0.1 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EGF82208.1 - 9.5e-05 22.8 0.2 0.00044 20.7 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGF82208.1 - 0.0011 18.9 11.2 0.017 15.0 1.6 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS CNH PF00780.22 EGF82208.1 - 0.077 12.6 0.0 1.4 8.4 0.0 2.2 1 1 0 1 1 1 0 CNH domain RHD3 PF05879.12 EGF82210.1 - 1.8e-212 707.5 14.7 1.5e-210 701.2 14.7 2.0 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EGF82210.1 - 7.4e-06 26.0 0.0 2.1e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGF82210.1 - 3.6e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 EGF82210.1 - 8e-05 22.0 0.1 0.00018 20.9 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 EGF82210.1 - 0.00029 21.1 0.0 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EGF82210.1 - 0.0085 16.3 1.3 0.19 12.0 0.0 2.8 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGF82210.1 - 0.018 15.5 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 EGF82210.1 - 0.035 13.4 0.5 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Septin HasA PF06438.12 EGF82210.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Heme-binding protein A (HasA) Ribosomal_L7Ae PF01248.26 EGF82212.1 - 4.3e-23 80.9 0.7 1e-22 79.7 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATPase_2 PF01637.18 EGF82212.1 - 0.075 12.9 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ras PF00071.22 EGF82213.1 - 1.9e-47 160.9 0.0 2.3e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF82213.1 - 1.2e-16 61.1 0.0 1.9e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF82213.1 - 3.5e-06 26.6 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF82213.1 - 0.00026 20.6 0.1 0.0026 17.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGF82213.1 - 0.0039 16.7 0.4 0.044 13.3 0.4 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EGF82213.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EGF82213.1 - 0.019 14.9 0.0 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EGF82213.1 - 0.028 14.0 0.0 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EGF82213.1 - 0.034 14.2 0.4 0.21 11.7 0.3 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGF82213.1 - 0.095 13.1 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_S13 PF00416.22 EGF82214.1 - 1.3e-23 83.8 0.1 1.5e-21 77.1 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 IMS_HHH PF11798.8 EGF82214.1 - 0.00056 20.1 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif FbpA PF05833.11 EGF82214.1 - 0.0057 15.5 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Pkinase PF00069.25 EGF82215.1 - 6.1e-45 153.6 0.0 1e-35 123.4 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82215.1 - 4.7e-17 62.1 0.0 2.4e-14 53.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF82215.1 - 0.00049 19.5 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF82215.1 - 0.0051 16.8 0.0 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF82215.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF82215.1 - 0.061 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EGF82215.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 EGF82216.1 - 2e-22 79.1 11.5 4.1e-05 24.3 0.1 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Bromodomain PF00439.25 EGF82216.1 - 6.7e-14 51.7 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain WD40_3 PF15911.5 EGF82216.1 - 0.002 18.1 0.5 3 7.9 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat eIF-1a PF01176.19 EGF82218.1 - 3.1e-10 39.7 0.0 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Translation initiation factor 1A / IF-1 Ank_4 PF13637.6 EGF82219.1 - 2.6e-21 75.7 0.1 5.1e-10 39.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) FYVE PF01363.21 EGF82219.1 - 6.9e-19 67.8 3.0 6.9e-19 67.8 3.0 3.0 3 0 0 3 3 2 1 FYVE zinc finger Ank_2 PF12796.7 EGF82219.1 - 6.5e-18 65.1 0.0 2e-08 34.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGF82219.1 - 1.1e-09 37.7 0.1 0.059 13.9 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGF82219.1 - 1.3e-08 34.9 0.3 0.19 12.1 0.0 3.7 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGF82219.1 - 6e-08 32.8 0.7 0.72 10.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat zf-RING_2 PF13639.6 EGF82219.1 - 1.4e-05 25.3 8.7 1.4e-05 25.3 8.7 4.0 4 0 0 4 4 4 1 Ring finger domain Pex24p PF06398.11 EGF82219.1 - 2.5e-05 23.4 2.8 5.9e-05 22.2 2.8 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin UBZ_FAAP20 PF15750.5 EGF82219.1 - 0.00026 20.8 0.3 0.00026 20.8 0.3 3.2 5 0 0 5 5 4 1 Ubiquitin-binding zinc-finger zf-RING_11 PF17123.5 EGF82219.1 - 0.0075 16.0 11.4 0.0075 16.0 11.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGF82219.1 - 0.19 12.1 12.4 0.13 12.6 7.9 3.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain FANCL_C PF11793.8 EGF82219.1 - 0.73 10.0 19.3 0.077 13.2 5.8 3.9 4 0 0 4 4 3 0 FANCL C-terminal domain Ssl1 PF04056.14 EGF82220.1 - 9.4e-76 253.9 0.0 1.4e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EGF82220.1 - 6.2e-17 61.6 9.9 6.2e-17 61.6 9.9 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EGF82220.1 - 9e-13 48.8 0.0 3.5e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EGF82220.1 - 1.7e-06 28.4 0.0 2.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EGF82220.1 - 0.00086 18.9 2.0 0.0014 18.1 2.0 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_3 PF13768.6 EGF82220.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Tetraspanin PF00335.20 EGF82221.1 - 1.3e-11 44.6 7.0 1.8e-11 44.2 7.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 EGF82221.1 - 0.011 15.9 3.7 0.011 15.9 3.7 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF4064) Thiolase_N PF00108.23 EGF82222.1 - 9.2e-90 300.5 4.0 1.2e-89 300.1 4.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF82222.1 - 4.4e-42 142.6 4.2 2.5e-41 140.2 0.5 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGF82222.1 - 5.2e-07 29.5 1.6 0.00022 20.9 0.2 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Guanylate_cyc PF00211.20 EGF82223.1 - 2e-90 301.3 0.6 1.1e-45 155.5 0.2 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 EGF82223.1 - 0.31 10.4 0.0 0.31 10.4 0.0 2.4 3 0 0 3 3 3 0 Heme NO binding associated Polysacc_deac_1 PF01522.21 EGF82224.1 - 4.9e-28 97.5 0.0 4.2e-27 94.5 0.0 2.1 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGF82224.1 - 0.014 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 RL11D PF11088.8 EGF82224.1 - 0.04 14.2 4.0 0.1 12.9 4.0 1.6 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Enamelin PF15362.6 EGF82224.1 - 1.3 7.3 13.7 1.7 6.9 13.7 1.0 1 0 0 1 1 1 0 Enamelin DUF5316 PF17247.2 EGF82226.1 - 0.23 11.5 5.4 0.095 12.7 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5316) SAUGI PF06106.11 EGF82227.1 - 0.091 13.3 0.5 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 S. aureus uracil DNA glycosylase inhibitor Nucleoside_tran PF01733.18 EGF82228.1 - 5e-29 101.7 7.7 5e-29 101.7 7.7 2.3 1 1 1 2 2 2 2 Nucleoside transporter LRR_9 PF14580.6 EGF82229.1 - 9.3e-64 214.1 37.3 3.3e-17 62.5 3.3 7.8 4 3 4 8 8 8 6 Leucine-rich repeat LRR_4 PF12799.7 EGF82229.1 - 4.2e-50 166.9 95.2 2.5e-08 34.1 0.0 16.8 10 4 5 18 18 18 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF82229.1 - 6.3e-40 134.7 88.6 1.2e-11 44.2 6.5 13.3 10 4 5 15 15 15 11 Leucine rich repeat I_LWEQ PF01608.17 EGF82229.1 - 0.0046 17.2 2.3 0.012 15.8 2.3 1.7 1 0 0 1 1 1 1 I/LWEQ domain RRF PF01765.19 EGF82229.1 - 0.039 13.9 3.0 0.13 12.2 3.0 2.0 1 0 0 1 1 1 0 Ribosome recycling factor SIR4_SID PF16991.5 EGF82229.1 - 0.71 9.9 7.0 0.45 10.6 0.4 3.2 3 0 0 3 3 3 0 Sir4 SID domain Ank_2 PF12796.7 EGF82230.1 - 2.9e-38 130.3 8.9 1.5e-10 41.5 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF82230.1 - 3.5e-30 104.0 7.5 1.3e-09 38.4 0.0 7.0 3 2 4 7 7 7 6 Ankyrin repeats (many copies) GDPD PF03009.17 EGF82230.1 - 2.3e-26 93.1 0.0 4.5e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.19 EGF82230.1 - 1.1e-25 91.4 12.0 3.1e-10 40.5 2.2 3.2 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 EGF82230.1 - 3.7e-22 78.1 2.8 1.3e-05 25.3 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGF82230.1 - 2.7e-21 75.0 10.4 4.6e-07 30.0 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 EGF82230.1 - 2.6e-18 64.2 9.6 0.0017 18.7 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat CH_2 PF06294.11 EGF82231.1 - 1.2e-32 111.9 0.0 2.2e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGF82231.1 - 6e-15 54.8 0.0 1.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 EGF82231.1 - 0.022 14.9 0.0 0.097 12.9 0.0 1.9 1 1 1 2 2 2 0 Calponin homology (CH) domain DUF4736 PF15883.5 EGF82231.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) Hexokinase_2 PF03727.16 EGF82232.1 - 2.4e-85 285.8 0.1 4.3e-85 285.0 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EGF82232.1 - 5.2e-69 232.1 0.1 7.3e-69 231.6 0.1 1.2 1 0 0 1 1 1 1 Hexokinase MarR_2 PF12802.7 EGF82232.1 - 0.12 12.3 0.1 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 MarR family MCM PF00493.23 EGF82233.1 - 5.3e-99 329.8 0.0 8.8e-99 329.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGF82233.1 - 1.1e-36 125.4 0.0 2e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGF82233.1 - 9.7e-26 90.0 0.5 2.5e-25 88.7 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGF82233.1 - 2.2e-16 60.3 0.1 7.3e-16 58.6 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGF82233.1 - 1.3e-08 34.5 0.0 1.3e-06 28.0 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGF82233.1 - 1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM2_N PF12619.8 EGF82233.1 - 4.8e-05 23.7 8.5 4.8e-05 23.7 8.5 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 AAA_3 PF07726.11 EGF82233.1 - 8.9e-05 22.4 0.0 0.003 17.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGF82233.1 - 0.01 15.6 0.0 0.28 10.9 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain zinc_ribbon_10 PF10058.9 EGF82233.1 - 0.23 11.2 1.5 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Complex1_LYR PF05347.15 EGF82234.1 - 1.7e-10 40.8 0.4 2.3e-10 40.4 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGF82234.1 - 0.00025 21.8 0.1 0.0003 21.5 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.22 EGF82235.1 - 4e-25 87.4 0.1 2.9e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGF82235.1 - 0.099 12.9 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 BRCA1-associated protein 2 Macoilin PF09726.9 EGF82235.1 - 0.58 8.6 15.7 0.0073 14.9 7.2 2.0 2 0 0 2 2 2 0 Macoilin family WD40 PF00400.32 EGF82236.1 - 5.3e-52 172.7 19.9 3.1e-09 37.3 1.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82236.1 - 2.4e-23 82.2 3.2 2.4e-07 30.9 0.0 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGF82236.1 - 1.5e-08 33.6 3.2 0.0022 16.6 0.0 3.1 1 1 1 3 3 3 3 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGF82236.1 - 5.7e-07 28.8 2.8 1 8.3 0.2 5.1 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGF82236.1 - 9.6e-07 28.4 0.1 0.26 10.6 0.0 3.7 2 1 1 3 3 3 3 WD40-like domain Nup160 PF11715.8 EGF82236.1 - 1.2e-05 24.2 8.4 0.011 14.5 0.4 3.9 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGF82236.1 - 6.2e-05 21.9 4.2 0.001 17.9 0.8 3.5 1 1 2 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.6 EGF82236.1 - 6.3e-05 22.4 1.0 3.4 6.9 0.0 4.0 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 EGF82236.1 - 0.00029 20.2 0.0 0.97 8.6 0.0 3.1 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2415 PF10313.9 EGF82236.1 - 0.0087 16.0 0.1 0.79 9.7 0.1 2.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) PALB2_WD40 PF16756.5 EGF82236.1 - 0.011 14.7 3.0 0.63 8.9 0.2 3.2 1 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain ArlS_N PF18719.1 EGF82236.1 - 0.039 14.1 0.0 3.6 7.8 0.0 3.0 2 1 0 3 3 3 0 ArlS sensor domain YABBY PF04690.13 EGF82237.1 - 7.2e-14 52.7 1.5 7.3e-14 52.6 1.5 1.0 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 EGF82237.1 - 8.9e-07 29.2 0.3 1.1e-06 29.0 0.3 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box Ccdc124 PF06244.12 EGF82237.1 - 7.6e-06 26.5 0.6 7.9e-06 26.5 0.6 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 EGF82237.1 - 2.7e-05 24.7 0.1 3.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain Carn_acyltransf PF00755.20 EGF82238.1 - 1.5e-170 568.7 0.0 1.7e-170 568.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_L18 PF17135.4 EGF82239.1 - 2.1e-93 310.9 3.3 2.4e-93 310.8 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGF82239.1 - 0.0016 19.1 0.3 0.0048 17.6 0.3 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PPR_3 PF13812.6 EGF82240.1 - 3.8e-11 42.9 0.7 0.024 14.7 0.0 5.1 4 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF82240.1 - 2e-06 27.9 0.2 0.58 10.4 0.0 4.4 4 0 0 4 4 4 2 PPR repeat family PPR_long PF17177.4 EGF82240.1 - 0.0011 18.4 0.7 2.2 7.6 0.1 3.5 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGF82240.1 - 7.2 7.1 9.0 2.8 8.4 0.1 4.5 5 0 0 5 5 5 0 PPR repeat Band_7 PF01145.25 EGF82241.1 - 6.5e-22 78.4 2.3 9.1e-22 77.9 2.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pyr_redox_2 PF07992.14 EGF82242.1 - 4.4e-65 219.8 8.3 6.7e-65 219.2 8.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGF82242.1 - 8.8e-44 148.3 0.7 2.5e-43 146.8 0.7 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGF82242.1 - 1.4e-20 73.6 9.7 8.7e-19 67.9 1.4 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF82242.1 - 4.1e-10 39.6 3.7 4.1e-10 39.6 3.7 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGF82242.1 - 1.4e-07 31.1 8.1 1.5e-05 24.4 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGF82242.1 - 2.1e-07 30.4 14.2 1.1e-06 28.0 7.1 3.0 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGF82242.1 - 2.5e-06 26.9 16.5 1.1e-05 24.7 2.5 3.9 4 1 0 4 4 4 2 FAD binding domain K_oxygenase PF13434.6 EGF82242.1 - 4.1e-06 26.2 0.8 0.002 17.3 0.1 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGF82242.1 - 6.5e-06 26.3 3.9 0.00093 19.4 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGF82242.1 - 9.6e-05 21.7 4.9 0.0008 18.7 0.2 2.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EGF82242.1 - 0.0013 17.5 16.5 0.0016 17.2 1.5 4.0 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EGF82242.1 - 0.0036 16.6 12.2 0.014 14.7 0.9 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGF82242.1 - 0.071 12.3 14.3 0.065 12.5 1.6 3.3 3 1 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 EGF82242.1 - 1.1 9.7 4.7 38 4.8 0.2 3.5 3 1 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EGF82242.1 - 2 7.4 6.4 0.55 9.2 0.1 2.7 4 0 0 4 4 4 0 Lycopene cyclase protein Tyr_Deacylase PF02580.16 EGF82243.1 - 4.9e-48 163.3 0.1 5.5e-48 163.1 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Adaptin_N PF01602.20 EGF82244.1 - 4e-99 332.6 9.9 5.6e-99 332.1 9.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EGF82244.1 - 2.2e-60 202.3 0.3 1e-59 200.1 0.1 2.3 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EGF82244.1 - 2.9e-58 195.7 0.1 6.5e-58 194.6 0.1 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 EGF82244.1 - 1.1e-09 38.5 8.8 3.2e-06 27.3 0.0 3.6 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGF82244.1 - 3.2e-09 36.2 0.1 0.011 15.9 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EGF82244.1 - 1.3e-08 35.1 0.0 0.0037 17.6 0.0 3.9 2 1 2 4 4 4 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EGF82244.1 - 0.011 15.9 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform Arm PF00514.23 EGF82244.1 - 0.046 13.8 1.0 12 6.1 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat VHL_C PF17211.3 EGF82244.1 - 0.091 12.8 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 VHL box domain HEAT_EZ PF13513.6 EGF82244.1 - 0.11 13.1 0.1 2.7 8.6 0.0 3.3 4 0 0 4 4 4 0 HEAT-like repeat ParcG PF10274.9 EGF82244.1 - 0.17 12.0 3.7 5.1 7.2 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein DUF5578 PF17741.1 EGF82244.1 - 0.17 11.3 6.5 5.6 6.3 0.7 3.5 2 1 2 4 4 4 0 Family of unknown function (DUF5578) Atg8 PF02991.16 EGF82245.1 - 6.3e-35 119.5 0.0 7.8e-35 119.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGF82245.1 - 4.9e-07 30.1 0.0 7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CHCH PF06747.13 EGF82246.1 - 4.8e-06 26.6 5.1 8.5e-06 25.8 5.1 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EGF82246.1 - 0.031 14.3 1.6 0.057 13.4 1.6 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2076 PF09849.9 EGF82246.1 - 0.17 11.9 22.6 0.6 10.1 22.6 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 EGF82246.1 - 4.5 7.1 10.5 5.3 6.9 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.25 EGF82247.1 - 8.7e-21 73.8 0.5 9.5e-21 73.7 0.5 1.0 1 0 0 1 1 1 1 Bromodomain IBR PF01485.21 EGF82248.1 - 1.2e-06 28.7 11.7 1.2e-06 28.7 11.7 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EGF82248.1 - 5.1e-05 23.1 9.9 5.1e-05 23.1 9.9 4.5 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGF82248.1 - 0.00035 20.4 10.1 0.00035 20.4 10.1 5.0 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF82248.1 - 0.00095 19.0 7.4 0.00095 19.0 7.4 6.1 6 1 0 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF82248.1 - 0.0016 18.3 9.7 0.0016 18.3 9.7 5.0 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF82248.1 - 0.02 14.8 9.9 0.02 14.8 9.9 5.1 4 2 1 5 5 5 0 Prokaryotic RING finger family 4 Peptidase_M49 PF03571.15 EGF82250.1 - 3.7e-238 791.4 0.0 6.1e-238 790.7 0.0 1.3 2 0 0 2 2 2 1 Peptidase family M49 Prefoldin PF02996.17 EGF82251.1 - 9.4e-20 70.7 6.4 7.7e-18 64.6 6.4 2.3 1 1 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 EGF82251.1 - 0.0024 18.1 0.4 0.0051 17.1 0.4 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter CALCOCO1 PF07888.11 EGF82251.1 - 0.0085 15.0 3.8 0.011 14.7 3.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like BAAT_C PF08840.11 EGF82251.1 - 0.0094 15.9 3.2 0.012 15.5 0.5 1.9 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF5115 PF17142.4 EGF82251.1 - 0.014 15.1 2.7 0.016 14.9 2.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5115) HCNGP PF07818.13 EGF82251.1 - 0.016 15.8 1.1 0.039 14.6 0.4 1.9 2 0 0 2 2 2 0 HCNGP-like protein DivIC PF04977.15 EGF82251.1 - 0.026 14.3 8.8 0.06 13.1 1.6 3.1 3 0 0 3 3 3 0 Septum formation initiator HD_3 PF13023.6 EGF82251.1 - 0.058 13.3 0.6 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 HD domain ACCA PF03255.14 EGF82251.1 - 0.059 13.2 4.9 0.17 11.7 0.5 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RasGAP_C PF03836.15 EGF82251.1 - 0.06 13.5 5.9 0.29 11.3 0.1 2.6 2 1 0 2 2 2 0 RasGAP C-terminus DASH_Dam1 PF08653.10 EGF82251.1 - 0.062 13.1 1.6 0.61 9.9 0.1 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 EGF82251.1 - 0.078 13.0 10.1 0.65 10.0 7.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Swi5 PF07061.11 EGF82251.1 - 0.094 12.8 3.5 0.17 12.0 0.2 2.6 2 1 0 2 2 2 0 Swi5 FlaC_arch PF05377.11 EGF82251.1 - 0.12 12.8 11.1 2 8.9 0.2 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 EGF82251.1 - 0.12 12.4 8.9 1.5 8.9 2.6 2.2 2 0 0 2 2 2 0 DivIVA protein Nas2_N PF18265.1 EGF82251.1 - 0.16 11.9 3.9 1.9 8.5 0.4 2.3 2 0 0 2 2 2 0 Nas2 N_terminal domain betaPIX_CC PF16523.5 EGF82251.1 - 0.24 11.3 6.5 0.79 9.6 2.4 2.2 2 0 0 2 2 2 0 betaPIX coiled coil TPR_MLP1_2 PF07926.12 EGF82251.1 - 0.32 11.1 10.6 0.12 12.4 1.6 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein P4Ha_N PF08336.11 EGF82251.1 - 0.62 10.1 8.2 0.075 13.0 1.3 2.3 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Csm1_N PF18504.1 EGF82251.1 - 0.68 10.3 8.8 1.9 8.9 1.0 3.1 3 1 0 3 3 3 0 Csm1 N-terminal domain FlxA PF14282.6 EGF82251.1 - 0.77 9.8 18.4 1.3 9.1 5.7 3.0 2 1 1 3 3 3 0 FlxA-like protein Fib_alpha PF08702.10 EGF82251.1 - 0.81 9.9 11.2 1 9.5 1.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 EGF82251.1 - 0.82 10.1 10.0 0.21 12.0 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 EGF82251.1 - 0.85 9.6 14.4 2 8.4 1.9 3.0 2 1 0 2 2 2 0 Prefoldin subunit YadA_stalk PF05662.14 EGF82251.1 - 1.3 9.4 4.3 23 5.5 0.2 2.9 2 1 1 3 3 3 0 Coiled stalk of trimeric autotransporter adhesin ZapB PF06005.12 EGF82251.1 - 1.5 9.4 15.0 0.094 13.2 4.0 2.6 2 1 1 3 3 3 0 Cell division protein ZapB Spc7 PF08317.11 EGF82251.1 - 1.5 7.6 11.8 0.92 8.3 2.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HR1 PF02185.16 EGF82251.1 - 2.3 8.4 11.7 0.57 10.3 0.3 3.2 3 1 1 4 4 3 0 Hr1 repeat DUF1664 PF07889.12 EGF82251.1 - 4.7 7.3 12.4 1.5 8.9 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) LPP PF04728.13 EGF82251.1 - 9 6.8 11.6 0.22 11.9 1.2 3.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Fes1 PF08609.10 EGF82252.1 - 0.24 12.3 1.2 9.9 7.1 0.1 2.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 RVT_1 PF00078.27 EGF82254.1 - 0.016 14.7 0.1 0.12 11.8 0.1 1.9 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) HATPase_c_3 PF13589.6 EGF82255.1 - 1.5e-10 41.0 0.0 1.8e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGF82255.1 - 1.5e-08 35.1 0.1 1.6e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_1 PF00515.28 EGF82256.1 - 4.2e-43 143.4 18.9 6.6e-06 25.7 0.5 11.4 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82256.1 - 8e-40 131.8 12.6 0.00011 22.0 0.4 11.3 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82256.1 - 2.3e-27 94.4 8.2 0.0018 17.9 1.7 8.8 6 3 3 9 9 9 6 TPR repeat TPR_17 PF13431.6 EGF82256.1 - 8.5e-23 79.1 10.0 0.00088 19.5 0.1 8.9 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82256.1 - 4.4e-20 72.1 1.0 0.00046 20.8 0.0 6.6 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82256.1 - 1.6e-18 65.3 18.5 0.18 12.1 0.3 10.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82256.1 - 6e-16 57.8 2.5 0.21 12.5 0.0 8.8 3 2 5 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82256.1 - 3.9e-13 49.5 20.1 0.0016 18.7 0.1 7.7 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGF82256.1 - 2.1e-11 44.1 9.2 0.0085 16.6 0.7 6.4 2 2 4 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF82256.1 - 3.1e-10 40.1 1.3 0.051 13.7 0.0 5.4 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82256.1 - 2.4e-09 36.6 12.1 0.13 12.3 0.1 7.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGF82256.1 - 1.2e-05 25.6 6.2 0.58 10.9 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGF82256.1 - 0.0018 18.4 2.4 1.5 8.9 0.1 4.9 2 2 1 3 3 3 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EGF82256.1 - 0.0018 18.5 12.3 0.44 10.8 0.0 5.3 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGF82256.1 - 0.0025 17.2 5.4 1.4 8.2 0.1 5.0 3 2 2 5 5 5 1 MalT-like TPR region TPR_3 PF07720.12 EGF82256.1 - 0.0027 17.7 0.3 0.0027 17.7 0.3 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 EGF82256.1 - 0.02 15.3 4.4 11 6.4 0.1 3.9 4 1 0 4 4 3 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 EGF82256.1 - 0.026 14.2 0.4 3.9 7.1 0.0 3.7 4 1 1 5 5 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 EGF82256.1 - 0.037 14.1 0.3 0.38 10.9 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGF82256.1 - 0.1 12.5 19.3 0.15 12.0 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat PSD5 PF07637.11 EGF82256.1 - 0.15 12.4 0.5 1.5 9.2 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1595) PPR PF01535.20 EGF82256.1 - 0.17 12.2 0.2 10 6.6 0.0 3.7 3 0 0 3 3 3 0 PPR repeat MIT PF04212.18 EGF82256.1 - 0.25 11.4 0.1 0.25 11.4 0.1 6.2 8 0 0 8 8 6 0 MIT (microtubule interacting and transport) domain DUF4810 PF16068.5 EGF82256.1 - 0.75 10.4 6.7 0.96 10.0 0.3 4.1 4 1 0 4 4 3 0 Domain of unknown function (DUF4810) ANAPC5 PF12862.7 EGF82256.1 - 6.3 6.9 7.4 12 6.0 0.1 3.5 5 0 0 5 5 3 0 Anaphase-promoting complex subunit 5 KAP PF05804.12 EGF82257.1 - 2.9e-188 627.4 30.9 5.4e-151 504.2 22.8 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Pex19 PF04614.12 EGF82257.1 - 0.1 12.3 0.5 0.24 11.2 0.5 1.5 1 0 0 1 1 1 0 Pex19 protein family Arm PF00514.23 EGF82257.1 - 0.14 12.3 0.1 49 4.2 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2103 PF09876.9 EGF82257.1 - 0.14 12.2 0.7 0.35 10.9 0.7 1.6 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) PP_kinase_N PF13089.6 EGF82257.1 - 2.4 8.5 5.7 5.3 7.4 0.8 3.3 3 1 0 3 3 3 0 Polyphosphate kinase N-terminal domain Peptidase_C65 PF10275.9 EGF82258.1 - 1.6e-58 198.0 0.0 2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EGF82258.1 - 0.0002 21.9 0.0 0.00071 20.1 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease MHB PF16525.5 EGF82259.1 - 0.026 14.8 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding DUF410 PF04190.13 EGF82259.1 - 0.032 14.0 0.1 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF410) FIBP PF05427.11 EGF82259.1 - 0.044 13.1 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) DNA_pol_E_B PF04042.16 EGF82260.1 - 0.092 12.1 0.5 0.16 11.3 0.5 1.3 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RUN PF02759.19 EGF82261.1 - 1.6e-15 57.2 0.0 4.1e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 RUN domain Par3_HAL_N_term PF12053.8 EGF82261.1 - 0.21 11.8 0.8 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 N-terminal of Par3 and HAL proteins Cortex-I_coil PF09304.10 EGF82261.1 - 1.2 9.4 12.8 0.27 11.5 2.8 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil TPR_MLP1_2 PF07926.12 EGF82261.1 - 4.9 7.2 12.7 2.9 7.9 8.2 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HORMA PF02301.18 EGF82262.1 - 3.3e-23 82.4 0.8 4.2e-23 82.1 0.8 1.1 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 EGF82262.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial HORMA domain 2 LSM PF01423.22 EGF82263.1 - 1.4e-17 63.1 0.0 1.6e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF82263.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain RRM_1 PF00076.22 EGF82264.1 - 8.7e-16 57.5 0.1 1.9e-06 27.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF82264.1 - 0.0019 18.0 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif Ribosomal_S13_N PF08069.12 EGF82264.1 - 1.4 9.0 3.3 1.1 9.4 0.4 2.2 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain RNA_pol_Rbc25 PF08292.12 EGF82264.1 - 6.5 7.0 6.6 0.92 9.7 0.2 2.7 3 1 0 3 3 3 0 RNA polymerase III subunit Rpc25 Paf67 PF10255.9 EGF82265.1 - 4.1e-164 546.4 3.3 5.2e-164 546.1 3.3 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 EGF82265.1 - 0.0059 16.4 0.1 0.035 13.9 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82265.1 - 0.013 15.8 0.4 0.44 10.9 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82265.1 - 0.029 14.5 0.0 0.092 12.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF82265.1 - 0.18 12.5 1.7 1 10.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat XisI PF08869.11 EGF82265.1 - 0.19 12.1 1.0 0.83 10.0 0.0 2.4 2 1 0 2 2 2 0 XisI protein TINF2_N PF14973.6 EGF82265.1 - 0.57 10.5 2.9 0.44 10.9 0.4 2.0 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus RPEL PF02755.15 EGF82266.1 - 8.3e-23 79.4 6.8 1.3e-05 24.7 0.1 4.6 4 0 0 4 4 4 4 RPEL repeat PIN_12 PF16289.5 EGF82266.1 - 0.017 15.6 2.3 0.028 14.9 1.8 1.6 1 1 0 1 1 1 0 PIN domain P2 PF07194.11 EGF82266.1 - 0.15 12.1 0.9 3.8 7.6 0.0 2.8 1 1 2 3 3 3 0 P2 response regulator binding domain CCDC74_C PF14917.6 EGF82266.1 - 0.16 12.5 7.3 0.52 10.8 6.6 1.9 1 1 1 2 2 2 0 Coiled coil protein 74, C terminal DUF2730 PF10805.8 EGF82266.1 - 0.59 10.3 5.1 0.89 9.7 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Glyco_tran_28_C PF04101.16 EGF82268.1 - 2.7e-20 73.0 0.0 3.3e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 EGF82268.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF4580 PF15162.6 EGF82268.1 - 0.13 11.8 0.6 0.77 9.3 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4580) DNA_pol3_delta2 PF13177.6 EGF82269.1 - 2.2e-10 40.6 0.4 6.4e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EGF82269.1 - 3e-06 27.7 0.2 8.7e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGF82269.1 - 5e-05 23.3 0.0 0.00023 21.1 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGF82269.1 - 0.00021 21.7 0.3 0.0037 17.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 EGF82269.1 - 0.00035 20.9 0.2 0.00035 20.9 0.2 2.0 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 EGF82269.1 - 0.0023 17.7 0.9 0.0056 16.5 0.9 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EGF82269.1 - 0.007 16.7 0.1 0.028 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA C-terminal domain AAA_22 PF13401.6 EGF82269.1 - 0.0091 16.3 1.7 0.044 14.0 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EGF82269.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain LPD24 PF18839.1 EGF82269.1 - 0.09 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 ABC_tran PF00005.27 EGF82269.1 - 0.099 13.2 0.2 0.17 12.4 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Galactosyl_T PF01762.21 EGF82270.1 - 2.8e-12 46.9 0.0 8.6e-10 38.8 0.0 2.2 1 1 1 2 2 2 2 Galactosyltransferase 2OG-FeII_Oxy_2 PF13532.6 EGF82271.1 - 2.2e-21 77.0 0.0 2.2e-20 73.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosom_S12_S23 PF00164.25 EGF82272.1 - 2.5e-49 165.6 0.4 3.1e-49 165.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Methyltransf_15 PF09445.10 EGF82272.1 - 0.0032 17.1 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase VWA_2 PF13519.6 EGF82273.1 - 4.5e-25 88.4 0.1 2.5e-24 86.0 0.1 2.2 3 0 0 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 EGF82273.1 - 6.6e-11 41.3 14.3 0.00028 20.6 1.5 3.6 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 EGF82273.1 - 6.8e-08 32.6 0.1 1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 EGF82273.1 - 0.5 10.2 2.7 1.5 8.6 0.4 2.3 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif SNAPc_SNAP43 PF09808.9 EGF82274.1 - 4.8e-16 59.3 0.1 7.2e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Sec1 PF00995.23 EGF82276.1 - 8.6e-114 381.8 3.2 1.1e-113 381.6 3.2 1.0 1 0 0 1 1 1 1 Sec1 family Ecm29 PF13001.7 EGF82276.1 - 0.0062 15.3 0.9 0.0062 15.3 0.9 1.7 2 0 0 2 2 2 1 Proteasome stabiliser PP2C PF00481.21 EGF82277.1 - 1e-36 126.9 0.0 1.3e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGF82277.1 - 1.6e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGF82277.1 - 5e-05 23.3 0.8 0.017 15.0 0.1 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) AAA_14 PF13173.6 EGF82277.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arrestin_N PF00339.29 EGF82278.1 - 2.5e-08 34.1 0.0 6.7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SH3_9 PF14604.6 EGF82278.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF82278.1 - 2.9e-06 26.9 0.0 5.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF82278.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Arrestin_C PF02752.22 EGF82278.1 - 0.81 10.1 6.8 3 8.3 0.3 3.8 4 1 0 4 4 4 0 Arrestin (or S-antigen), C-terminal domain ABC_tran PF00005.27 EGF82279.1 - 3.9e-31 108.4 0.0 9.8e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF82279.1 - 3.1e-17 63.3 0.9 5.6e-11 42.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGF82279.1 - 2.9e-15 56.2 34.0 4.1e-15 55.7 34.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 EGF82279.1 - 0.00043 19.8 0.1 0.059 12.8 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGF82279.1 - 0.0047 17.5 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF82279.1 - 0.0047 16.7 0.2 0.062 13.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGF82279.1 - 0.0062 16.3 0.0 1.7 8.3 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EGF82279.1 - 0.0067 16.6 0.0 0.082 13.2 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGF82279.1 - 0.045 13.5 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 EGF82279.1 - 0.1 11.2 0.0 2.5 6.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGF82279.1 - 0.12 12.0 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Peptidase_S41 PF03572.18 EGF82280.1 - 2.8e-10 40.0 0.0 5.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Peptidase_M36 PF02128.15 EGF82281.1 - 5.7e-58 196.9 0.3 6.4e-58 196.7 0.3 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) DUF4377 PF14302.6 EGF82282.1 - 0.057 13.5 0.4 0.088 12.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) Asp PF00026.23 EGF82283.1 - 9e-15 54.9 0.3 3.7e-14 52.9 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82283.1 - 8.3e-05 22.4 0.0 0.00044 20.1 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Diacid_rec PF05651.13 EGF82283.1 - 0.15 11.7 0.7 0.34 10.6 0.7 1.5 1 0 0 1 1 1 0 Putative sugar diacid recognition DUF5001 PF16392.5 EGF82286.1 - 0.019 14.9 0.4 0.56 10.2 0.0 2.9 2 1 0 2 2 2 0 Ig-like domain Nup54 PF13874.6 EGF82286.1 - 0.092 12.9 7.3 0.11 12.6 5.9 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 BRE1 PF08647.11 EGF82286.1 - 0.21 11.7 10.9 0.57 10.3 10.9 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.9 EGF82286.1 - 0.3 10.1 10.7 0.45 9.6 7.5 2.6 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LXG PF04740.12 EGF82286.1 - 0.41 10.3 10.0 0.16 11.7 3.1 2.9 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF2203 PF09969.9 EGF82286.1 - 0.48 11.2 2.9 4.1 8.1 1.6 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 EGF82286.1 - 0.49 11.0 12.9 0.11 13.1 9.1 1.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_S17_N PF16205.5 EGF82286.1 - 3.6 8.0 5.3 45 4.5 0.0 3.5 4 0 0 4 4 4 0 Ribosomal_S17 N-terminal SlyX PF04102.12 EGF82286.1 - 9.3 6.9 9.6 7.2 7.3 2.4 3.1 2 1 1 3 3 3 0 SlyX CTC1_2 PF15491.6 EGF82287.1 - 0.013 14.8 0.1 0.023 14.0 0.0 1.5 1 1 1 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 CSTF1_dimer PF16699.5 EGF82287.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain HEAT PF02985.22 EGF82289.1 - 1.9e-18 65.0 6.5 0.00024 21.1 0.0 9.4 9 1 1 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 EGF82289.1 - 4.5e-15 55.8 10.0 0.72 10.4 0.0 10.1 8 1 0 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 EGF82289.1 - 6.8e-14 52.0 1.7 0.066 13.6 0.0 6.7 4 2 3 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF82289.1 - 6.2e-08 33.1 0.6 0.0018 18.9 0.1 4.3 3 1 1 4 4 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGF82289.1 - 8e-07 29.2 3.1 0.0032 17.5 0.7 4.6 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EGF82289.1 - 2.3e-06 27.4 0.1 0.00076 19.3 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EGF82289.1 - 0.00089 17.9 2.3 0.0021 16.7 0.4 2.5 3 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 EGF82289.1 - 0.0024 17.5 0.1 16 5.0 0.0 4.9 5 1 2 7 7 7 0 CLASP N terminal RTP1_C1 PF10363.9 EGF82289.1 - 0.0025 18.0 0.3 0.015 15.5 0.1 2.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CENP-B_dimeris PF09026.10 EGF82289.1 - 0.023 15.1 4.0 0.054 13.9 4.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3437 PF11919.8 EGF82289.1 - 0.051 13.5 0.0 29 4.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) RXT2_N PF08595.11 EGF82289.1 - 0.28 11.2 1.6 0.54 10.3 1.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EGF82289.1 - 2.4 8.6 9.7 4.5 7.7 9.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dynamin_N PF00350.23 EGF82290.1 - 2.9e-19 69.8 0.1 9.6e-19 68.1 0.1 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGF82290.1 - 4.9e-10 39.5 0.0 2e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF82290.1 - 5.3e-07 29.4 0.4 0.0058 16.2 0.3 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF82290.1 - 0.0021 18.0 0.1 3.1 7.7 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 EGF82290.1 - 0.0074 15.9 0.1 0.83 9.2 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 EGF82290.1 - 0.0081 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EGF82290.1 - 0.028 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Septin TsaE PF02367.17 EGF82290.1 - 0.04 13.9 0.0 0.57 10.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EGF82290.1 - 0.08 12.7 0.0 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGF82290.1 - 0.087 12.6 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EGF82290.1 - 0.089 13.0 0.0 3.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EGF82290.1 - 0.12 11.9 0.2 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Sod_Cu PF00080.20 EGF82291.1 - 7.6e-44 149.3 0.2 1.1e-43 148.8 0.2 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BES1_N PF05687.13 EGF82291.1 - 8.8 6.7 6.2 20 5.6 0.0 2.4 1 1 1 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal DUF1664 PF07889.12 EGF82292.1 - 0.24 11.4 2.2 0.71 9.9 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.6 EGF82293.1 - 2.5e-11 43.2 7.8 5.6e-11 42.1 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF82293.1 - 1.1e-10 41.2 6.8 2e-10 40.4 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF82293.1 - 5.5e-10 39.4 9.1 1.1e-09 38.5 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGF82293.1 - 1.4e-09 37.6 3.9 2.5e-09 36.8 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF82293.1 - 1.5e-08 34.5 7.8 3.3e-08 33.4 7.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGF82293.1 - 3.3e-08 33.4 5.3 5.7e-08 32.6 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGF82293.1 - 5.9e-08 32.7 7.8 9.5e-08 32.1 7.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGF82293.1 - 1.4e-07 31.2 6.0 2.5e-07 30.4 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGF82293.1 - 3e-05 24.2 4.4 3e-05 24.2 4.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 EGF82293.1 - 0.0013 18.7 1.0 0.0023 17.9 1.0 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 EGF82293.1 - 0.01 15.6 2.8 0.023 14.5 2.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGF82293.1 - 0.016 15.2 2.2 0.016 15.2 2.2 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGF82293.1 - 0.018 14.9 3.2 0.033 14.0 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.15 EGF82293.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 U-box domain Rtf2 PF04641.12 EGF82293.1 - 0.066 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-P11 PF03854.14 EGF82293.1 - 0.17 11.5 6.8 0.33 10.7 6.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger IBR PF01485.21 EGF82293.1 - 2.8 8.2 8.1 3.5 7.9 6.1 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DEAD PF00270.29 EGF82294.1 - 2e-46 158.0 0.0 3.4e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF82294.1 - 3.7e-29 101.3 0.1 1.2e-26 93.2 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 EGF82294.1 - 0.017 13.9 3.8 2.3 6.9 0.1 3.5 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Snf7 PF03357.21 EGF82295.1 - 0.01 15.4 3.2 0.01 15.4 3.2 1.8 1 1 1 2 2 2 0 Snf7 VP9 PF09625.10 EGF82295.1 - 0.017 15.3 0.2 0.035 14.3 0.2 1.5 1 0 0 1 1 1 0 VP9 protein Vir_act_alpha_C PF10400.9 EGF82295.1 - 0.041 14.6 0.1 0.041 14.6 0.1 2.6 2 1 0 2 2 2 0 Virulence activator alpha C-term Tsc35 PF15079.6 EGF82295.1 - 0.44 10.1 9.2 0.028 14.0 1.4 2.2 1 1 0 2 2 2 0 Testis-specific protein 35 Peptidase_M36 PF02128.15 EGF82297.1 - 1.6e-66 225.0 0.8 1.7e-66 224.9 0.8 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF82297.1 - 0.024 14.5 0.5 0.042 13.7 0.5 1.4 1 1 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain MR_MLE_N PF02746.16 EGF82297.1 - 0.089 13.0 0.4 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF4200 PF13863.6 EGF82298.1 - 0.0013 19.1 0.2 0.0016 18.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_23 PF13476.6 EGF82298.1 - 0.69 10.4 7.2 0.9 10.0 7.2 1.1 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EGF82299.1 - 0.00011 22.7 0.3 0.56 10.8 0.0 3.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF82299.1 - 0.082 13.5 0.6 45 4.8 0.1 3.6 2 2 0 2 2 2 0 Ankyrin repeats (many copies) Longin PF13774.6 EGF82300.1 - 0.00071 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain 7TM-7TMR_HD PF07698.11 EGF82300.1 - 0.012 15.3 1.8 0.012 15.3 1.8 2.0 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Cyt_bd_oxida_II PF02322.15 EGF82300.1 - 0.018 14.4 2.7 0.029 13.7 2.5 1.3 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF2909 PF11137.8 EGF82300.1 - 0.37 10.8 3.6 0.43 10.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DivIC PF04977.15 EGF82301.1 - 0.0067 16.2 1.9 0.14 11.9 0.1 2.2 2 0 0 2 2 2 1 Septum formation initiator Apolipoprotein PF01442.18 EGF82301.1 - 0.015 15.2 0.7 0.019 14.8 0.7 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Snapin_Pallidin PF14712.6 EGF82301.1 - 0.031 14.7 1.3 0.043 14.2 1.1 1.4 1 1 0 1 1 1 0 Snapin/Pallidin DUF2779 PF11074.8 EGF82301.1 - 0.076 13.5 0.5 0.12 12.9 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) YkyA PF10368.9 EGF82301.1 - 0.12 12.0 4.2 0.17 11.6 4.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF1664 PF07889.12 EGF82301.1 - 0.15 12.1 3.0 0.22 11.6 2.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sulphotransf PF09037.10 EGF82301.1 - 0.17 11.4 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 Stf0 sulphotransferase DUF3584 PF12128.8 EGF82301.1 - 0.19 9.2 3.5 0.24 8.9 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 EGF82301.1 - 0.2 11.9 7.2 0.56 10.4 0.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EGF82301.1 - 0.29 11.2 8.9 0.51 10.4 8.9 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 EGF82302.1 - 0.0017 18.7 0.3 0.0022 18.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) FliD_C PF07195.12 EGF82302.1 - 0.012 15.1 2.2 0.015 14.8 2.2 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4246 PF14033.6 EGF82303.1 - 5e-20 72.0 0.1 6.7e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Taxilin PF09728.9 EGF82304.1 - 0.00066 19.0 8.7 0.00084 18.6 8.7 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein CC2-LZ PF16516.5 EGF82304.1 - 0.0023 18.3 2.1 0.0037 17.6 2.1 1.3 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 EGF82304.1 - 0.0045 16.1 3.0 0.0058 15.7 3.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EGF82304.1 - 0.0077 16.5 2.0 0.012 15.9 2.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Tup_N PF08581.10 EGF82304.1 - 0.021 15.1 3.4 0.043 14.1 3.4 1.5 1 0 0 1 1 1 0 Tup N-terminal DUF1640 PF07798.11 EGF82304.1 - 0.023 14.8 2.8 0.04 14.0 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF3841 PF12952.7 EGF82304.1 - 0.028 14.2 1.5 0.04 13.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) TPR_MLP1_2 PF07926.12 EGF82304.1 - 0.075 13.1 0.4 0.075 13.1 0.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 EGF82304.1 - 0.096 13.1 0.7 0.18 12.2 0.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 EGF82304.1 - 0.13 12.9 1.2 0.48 11.1 0.1 2.4 2 1 1 3 3 3 0 SlyX FapA PF03961.13 EGF82304.1 - 0.58 8.7 3.4 0.72 8.4 3.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1294 PF06961.13 EGF82305.1 - 8.3e-20 70.8 1.4 9.5e-20 70.6 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) MLVIN_C PF18697.1 EGF82305.1 - 0.0084 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Vps35 PF03635.17 EGF82306.1 - 7.4e-284 943.8 0.0 8.4e-284 943.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 SCAMP PF04144.13 EGF82308.1 - 3.3e-48 164.3 16.8 4.2e-48 163.9 16.8 1.1 1 0 0 1 1 1 1 SCAMP family SCAMP PF04144.13 EGF82309.1 - 1.1e-28 100.7 5.9 1.6e-28 100.2 5.9 1.2 1 0 0 1 1 1 1 SCAMP family Amelin PF05111.12 EGF82309.1 - 0.00072 18.8 7.8 0.00096 18.4 7.8 1.1 1 0 0 1 1 1 1 Ameloblastin precursor (Amelin) SKG6 PF08693.10 EGF82309.1 - 0.19 11.2 0.2 0.19 11.2 0.2 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain NUDIX PF00293.28 EGF82310.1 - 1.3e-09 38.1 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Diphthamide_syn PF01866.17 EGF82311.1 - 1.6e-114 382.4 0.0 2.2e-114 382.0 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Isy1 PF06246.12 EGF82312.1 - 2.1e-76 256.9 5.7 2.3e-76 256.7 5.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family LPD5 PF18799.1 EGF82312.1 - 0.035 14.5 0.8 0.077 13.4 0.9 1.7 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 5 XRN_N PF03159.18 EGF82313.1 - 1.9e-37 129.0 0.0 1.9e-37 129.0 0.0 3.3 2 2 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGF82313.1 - 0.0052 15.8 0.0 0.0052 15.8 0.0 3.7 2 2 1 3 3 3 2 Xrn1 helical domain UCH PF00443.29 EGF82316.1 - 7.9e-44 150.1 1.1 1e-42 146.4 1.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF82316.1 - 4.2e-19 69.3 9.6 2.9e-18 66.6 9.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGF82316.1 - 7.7e-07 29.4 3.0 7.7e-07 29.4 3.0 4.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Clat_adaptor_s PF01217.20 EGF82317.1 - 1.2e-46 158.2 0.1 1.3e-46 158.0 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pept_tRNA_hydro PF01195.19 EGF82318.1 - 3.7e-33 114.9 0.0 4.4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Fis1_TPR_C PF14853.6 EGF82319.1 - 4.5e-23 81.1 1.0 7.8e-23 80.3 1.0 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGF82319.1 - 2.3e-16 59.1 0.1 4.8e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGF82319.1 - 0.002 18.1 1.0 0.0036 17.3 0.4 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF82319.1 - 0.013 16.0 0.6 0.034 14.7 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82319.1 - 0.024 15.3 0.9 0.49 11.1 0.1 2.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82319.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF82319.1 - 0.06 14.0 1.0 0.24 12.1 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82319.1 - 0.076 13.9 0.2 0.46 11.4 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat dDENN PF03455.19 EGF82320.1 - 0.017 15.1 0.6 0.06 13.3 0.1 1.9 2 0 0 2 2 2 0 dDENN domain GIT_CC PF16559.5 EGF82320.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-C2H2 PF00096.26 EGF82320.1 - 0.14 12.7 13.1 0.44 11.1 1.1 2.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type Ecl1 PF12855.7 EGF82321.1 - 2.2e-08 35.4 16.5 2.2e-08 35.4 16.5 2.3 1 1 1 2 2 2 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 EGF82321.1 - 0.027 14.4 0.7 0.065 13.2 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) C1_2 PF03107.16 EGF82321.1 - 0.031 14.6 2.2 0.081 13.3 2.2 1.7 1 0 0 1 1 1 0 C1 domain TSP9 PF11493.8 EGF82321.1 - 0.091 13.4 0.1 0.77 10.5 0.0 2.4 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 zf-C6H2 PF15801.5 EGF82321.1 - 0.22 11.8 2.5 0.54 10.6 2.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGF82321.1 - 0.32 11.1 5.5 0.12 12.4 1.3 2.2 2 0 0 2 2 2 0 MYND finger zf-FLZ PF04570.14 EGF82321.1 - 1.2 8.7 4.7 5.9 6.4 2.7 2.7 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DUF3123 PF11321.8 EGF82321.1 - 1.6 9.4 12.1 0.48 11.1 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) MIG-14_Wnt-bd PF06664.12 EGF82322.1 - 0.45 9.7 20.8 1.3 8.2 5.8 2.3 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF4231 PF14015.6 EGF82322.1 - 1.4 9.4 12.8 1.5 9.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) adh_short PF00106.25 EGF82323.1 - 1e-24 87.1 0.1 1.7e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF82323.1 - 3.6e-22 79.1 0.5 5e-22 78.6 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF82323.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Dimeth_Pyl PF09505.10 EGF82323.1 - 0.072 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Mpv17_PMP22 PF04117.12 EGF82324.1 - 3.1e-17 62.5 1.9 3.1e-17 62.5 1.9 1.6 1 1 1 2 2 2 1 Mpv17 / PMP22 family Polyhedrin PF00738.18 EGF82324.1 - 0.012 14.9 0.2 0.015 14.7 0.2 1.0 1 0 0 1 1 1 0 Polyhedrin ICMT PF04140.14 EGF82325.1 - 2.3e-26 92.0 0.3 4.5e-26 91.1 0.3 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGF82325.1 - 8e-12 45.5 1.3 8e-12 45.5 1.3 1.7 2 1 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 EGF82325.1 - 0.00037 20.0 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 EGF82325.1 - 0.029 13.9 2.1 0.061 12.8 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Auto_anti-p27 PF06677.12 EGF82326.1 - 8.4e-24 83.4 14.4 4.5e-14 52.3 1.0 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NICE-1 PF15845.5 EGF82326.1 - 0.19 12.5 3.3 15 6.5 0.2 2.5 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Ank_4 PF13637.6 EGF82327.1 - 1.2e-26 92.7 0.6 3.3e-10 40.3 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF82327.1 - 2e-22 79.6 1.0 5.8e-16 58.9 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGF82327.1 - 6.1e-22 77.0 6.2 3.2e-05 24.2 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EGF82327.1 - 2.1e-21 73.7 3.3 5.3e-05 23.3 0.1 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGF82327.1 - 1.7e-18 66.4 2.0 6.1e-10 39.2 0.2 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) MatE PF01554.18 EGF82328.1 - 2.6e-60 202.7 25.0 2.2e-34 118.5 7.6 3.0 4 0 0 4 4 4 2 MatE zf-MIZ PF02891.20 EGF82329.1 - 2.7e-17 62.2 4.7 5.9e-17 61.1 4.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EGF82329.1 - 2.2e-06 27.3 0.0 4.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EGF82329.1 - 7.9e-05 22.4 2.5 0.00021 21.0 2.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PINIT PF14324.6 EGF82329.1 - 0.00011 22.5 0.1 0.00037 20.9 0.1 1.9 1 0 0 1 1 1 1 PINIT domain Prok-RING_4 PF14447.6 EGF82329.1 - 0.22 11.4 3.3 0.48 10.3 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 F-box-like PF12937.7 EGF82331.1 - 0.076 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like Peptidase_C12 PF01088.21 EGF82332.1 - 1.2e-58 198.4 0.0 1.3e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HycA_repressor PF11046.8 EGF82333.1 - 0.016 15.4 1.6 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Transcriptional repressor of hyc and hyp operons GlnE PF03710.15 EGF82333.1 - 0.07 12.5 1.8 0.47 9.8 0.3 2.2 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase Rab5ip PF07019.12 EGF82334.1 - 2.6e-21 76.0 9.2 3.1e-21 75.8 9.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) CPSase_L_D2 PF02786.17 EGF82335.1 - 2.3e-75 252.7 0.0 4.3e-75 251.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGF82335.1 - 4.3e-63 212.7 0.0 7.1e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGF82335.1 - 6.4e-39 132.9 0.1 1.6e-38 131.6 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGF82335.1 - 2.5e-31 108.0 0.0 1.2e-30 105.8 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGF82335.1 - 1.3e-28 100.3 0.0 2.7e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGF82335.1 - 4.4e-14 52.1 2.9 8.4e-14 51.2 2.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EGF82335.1 - 8.6e-08 32.4 0.0 1.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EGF82335.1 - 1.3e-07 31.4 0.0 3.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGF82335.1 - 2.4e-06 27.2 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGF82335.1 - 8.4e-06 25.5 1.3 0.011 15.6 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 EGF82335.1 - 2.3e-05 24.1 0.1 9.4e-05 22.1 0.0 2.1 2 1 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 EGF82335.1 - 8.8e-05 23.2 1.0 2.9 8.6 0.3 3.5 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EGF82335.1 - 0.0089 15.3 0.3 0.11 11.7 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 EGF82335.1 - 0.029 13.6 0.0 0.09 12.0 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp M3 PF09213.10 EGF82336.1 - 0.1 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 M3 V-SNARE_C PF12352.8 EGF82337.1 - 9.1e-18 64.3 6.8 9.1e-18 64.3 6.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EGF82337.1 - 2.9e-15 56.4 3.1 2.9e-15 56.4 3.1 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 EGF82337.1 - 0.0024 17.8 0.5 0.0024 17.8 0.5 2.4 2 2 0 2 2 2 1 Sec20 KNOX2 PF03791.13 EGF82337.1 - 0.17 11.4 1.9 0.69 9.5 0.2 2.2 2 0 0 2 2 2 0 KNOX2 domain DUF3619 PF12279.8 EGF82337.1 - 0.26 11.6 1.8 0.59 10.5 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) OppC_N PF12911.7 EGF82337.1 - 1.2 9.2 4.8 0.36 10.8 1.9 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Amino_oxidase PF01593.24 EGF82338.1 - 9.9e-16 58.1 0.0 1.4e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGF82338.1 - 5e-13 49.1 0.0 9.9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGF82338.1 - 0.0013 18.4 0.4 0.0028 17.3 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase CMAS PF02353.20 EGF82339.1 - 8e-73 245.1 0.0 1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGF82339.1 - 3.3e-12 46.9 0.0 7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF82339.1 - 2.1e-10 41.1 0.0 4.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF82339.1 - 1.9e-07 31.1 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF82339.1 - 7.3e-07 29.1 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF82339.1 - 1.3e-05 25.9 0.0 4e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF82339.1 - 0.0025 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Spermine_synth PF01564.17 EGF82339.1 - 0.0037 16.7 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_18 PF12847.7 EGF82339.1 - 0.0048 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGF82339.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 EGF82339.1 - 0.019 14.5 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Cons_hypoth95 PF03602.15 EGF82339.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 EGF82339.1 - 0.028 13.6 0.1 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase ADH_zinc_N PF00107.26 EGF82339.1 - 0.06 13.3 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF938 PF06080.12 EGF82339.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 EGF82339.1 - 0.085 13.9 0.0 0.24 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EGF82339.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Bacteriocin_IIc PF10439.9 EGF82340.1 - 0.63 10.2 12.5 1.3 9.2 1.6 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Tim17 PF02466.19 EGF82340.1 - 1.2 9.5 6.8 10 6.5 6.8 2.1 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family PEX11 PF05648.14 EGF82341.1 - 1.3e-29 103.3 0.5 1.5e-29 103.1 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TPR_14 PF13428.6 EGF82342.1 - 2.1e-12 46.7 1.5 11 7.2 0.0 10.0 11 1 1 12 12 12 2 Tetratricopeptide repeat Suf PF05843.14 EGF82342.1 - 1.9e-09 37.9 3.8 0.046 13.7 0.1 6.2 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EGF82342.1 - 7.6e-08 32.4 2.8 0.18 11.8 0.1 5.4 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGF82342.1 - 0.00032 20.6 4.1 1.1 9.6 0.0 6.0 9 0 0 9 9 9 1 Tetratricopeptide repeat RPN7 PF10602.9 EGF82342.1 - 0.0014 18.4 0.0 0.012 15.3 0.0 2.6 4 0 0 4 4 4 1 26S proteasome subunit RPN7 NRDE-2 PF08424.10 EGF82342.1 - 0.0026 17.0 4.8 2.3 7.3 0.0 5.4 4 2 1 5 5 5 1 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 EGF82342.1 - 0.018 15.2 0.1 18 5.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82342.1 - 0.024 14.7 0.1 2.3 8.4 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF82342.1 - 0.092 13.3 0.6 19 5.8 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I_2 PF17014.5 EGF82342.1 - 0.099 12.8 0.1 0.53 10.4 0.1 2.1 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Polysacc_deac_1 PF01522.21 EGF82343.1 - 9.9e-23 80.4 0.0 1.7e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGF82343.1 - 0.017 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF4246 PF14033.6 EGF82344.1 - 6.4e-87 292.5 0.0 9.8e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) YqfQ PF14181.6 EGF82344.1 - 0.0053 17.0 0.0 0.0053 17.0 0.0 1.9 2 0 0 2 2 2 1 YqfQ-like protein F-box-like PF12937.7 EGF82345.1 - 0.044 13.7 0.5 0.12 12.3 0.5 1.7 1 0 0 1 1 1 0 F-box-like Robl_LC7 PF03259.17 EGF82346.1 - 4.5e-07 29.5 0.1 0.00037 20.2 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Usp PF00582.26 EGF82347.1 - 2.4e-20 73.5 0.0 2.7e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Polysacc_deac_1 PF01522.21 EGF82348.1 - 1.6e-31 108.8 0.0 2.5e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGF82348.1 - 1.9e-15 57.0 43.2 7e-08 32.8 22.1 2.4 2 0 0 2 2 2 2 Chitin recognition protein CBFD_NFYB_HMF PF00808.23 EGF82349.1 - 2.6e-18 66.0 0.3 5.5e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGF82349.1 - 1.2e-14 54.8 0.8 2e-14 54.1 0.8 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SAE2 PF08573.10 EGF82349.1 - 0.061 14.4 0.5 0.18 12.9 0.1 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Snf7 PF03357.21 EGF82350.1 - 1.9e-15 56.9 16.1 2.8e-15 56.3 16.1 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EGF82350.1 - 0.00081 19.4 4.5 0.0012 18.9 4.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 EGF82350.1 - 0.028 14.1 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Foie-gras_1 PF11817.8 EGF82351.1 - 2.1e-37 129.1 0.0 1.4e-35 123.2 0.0 2.3 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EGF82351.1 - 2.8e-22 79.2 0.1 6.3e-15 55.0 0.1 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EGF82351.1 - 0.00012 22.0 0.0 0.00054 19.9 0.0 2.0 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 EGF82351.1 - 0.088 13.1 0.1 3.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 EGF82351.1 - 0.14 11.6 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EGF82351.1 - 0.57 10.4 2.4 28 5.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MARVEL PF01284.23 EGF82353.1 - 1.9e-05 24.7 13.2 2.8e-05 24.2 13.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain AMPK1_CBM PF16561.5 EGF82354.1 - 2e-32 111.3 0.1 2.9e-32 110.7 0.1 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGF82354.1 - 2.4e-21 75.8 0.6 5.2e-21 74.7 0.6 1.6 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 EGF82354.1 - 0.0074 16.9 0.1 0.013 16.1 0.1 1.3 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Peptidase_C14 PF00656.22 EGF82355.1 - 1.1e-50 172.9 0.0 1.6e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DUF2956 PF11169.8 EGF82355.1 - 0.043 14.0 0.4 0.092 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) RabGAP-TBC PF00566.18 EGF82357.1 - 7.9e-10 38.7 0.9 4e-06 26.7 0.1 3.0 2 1 0 2 2 2 2 Rab-GTPase-TBC domain DUF3447 PF11929.8 EGF82357.1 - 0.1 12.5 2.4 3.1 7.8 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) PP2 PF14299.6 EGF82358.1 - 7.4e-22 78.0 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box-like PF12937.7 EGF82358.1 - 2.8e-05 23.9 0.3 8e-05 22.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF82358.1 - 0.0016 18.2 0.5 0.0061 16.4 0.5 2.0 1 0 0 1 1 1 1 F-box domain Trehalase PF01204.18 EGF82360.1 - 1.6e-153 512.3 0.0 1.9e-153 512.0 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EGF82360.1 - 7.1e-15 54.4 0.3 1.6e-14 53.3 0.3 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ribo_biogen_C PF04034.13 EGF82361.1 - 2.4e-33 114.5 0.5 7.1e-31 106.6 0.0 2.6 2 1 1 3 3 3 2 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGF82361.1 - 9.4e-15 54.1 0.1 2.2e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI TOM13 PF08219.11 EGF82363.1 - 0.042 13.8 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Outer membrane protein TOM13 ACBP PF00887.19 EGF82364.1 - 3.7e-28 97.6 0.6 4e-28 97.4 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein F_actin_cap_B PF01115.17 EGF82368.1 - 9.1e-99 329.9 0.0 1.1e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Surp PF01805.20 EGF82369.1 - 1.8e-12 47.0 0.1 5.4e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 EGF82369.1 - 1.4e-10 40.8 0.4 8.3e-10 38.4 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGF82369.1 - 0.00038 21.2 0.0 0.00098 19.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EGF82369.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Transformer PF06495.11 EGF82369.1 - 0.16 12.0 16.8 0.42 10.7 16.8 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein FancD2 PF14631.6 EGF82370.1 - 1.4e-133 446.9 52.6 4.7e-65 219.9 3.5 4.2 3 1 1 4 4 4 3 Fanconi anaemia protein FancD2 nuclease VSG_B PF13206.6 EGF82370.1 - 1.6 7.9 11.2 2.7 7.2 11.2 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain RRM_1 PF00076.22 EGF82371.1 - 4.7e-19 68.0 0.0 7.8e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMP24_GP25L PF01105.24 EGF82372.1 - 9.1e-34 117.0 0.0 1.1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AcylCoA_dehyd_C PF12186.8 EGF82372.1 - 0.062 13.4 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal SET PF00856.28 EGF82373.1 - 7.1e-12 46.0 0.0 4.1e-11 43.6 0.0 2.4 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGF82373.1 - 9.2e-07 29.6 0.2 2.9e-06 28.0 0.2 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding TPR_1 PF00515.28 EGF82374.1 - 4.6e-10 38.9 12.4 0.00051 19.8 0.4 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82374.1 - 2.9e-09 36.4 15.7 0.00047 20.2 0.3 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82374.1 - 6.4e-09 35.3 14.2 0.14 12.4 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82374.1 - 1.5e-05 25.1 4.6 0.19 12.2 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82374.1 - 3.1e-05 23.7 4.1 0.009 16.0 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82374.1 - 7.7e-05 23.2 7.4 4 8.5 0.0 6.5 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82374.1 - 0.00016 21.9 16.7 1.3 9.4 0.1 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGF82374.1 - 0.0015 18.9 0.0 1.5 9.2 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82374.1 - 0.0015 19.1 10.1 0.26 12.0 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF82374.1 - 0.0026 18.2 8.6 0.22 12.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF82374.1 - 0.0038 16.6 4.5 0.8 9.0 0.2 3.5 3 0 0 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 EGF82374.1 - 0.0094 16.5 9.0 1.5 9.6 0.1 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82374.1 - 0.19 11.6 8.2 17 5.4 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MRF_C2 PF13888.6 EGF82374.1 - 0.2 11.5 0.7 0.66 9.9 0.7 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 ANAPC3 PF12895.7 EGF82374.1 - 0.54 10.5 5.8 0.65 10.3 0.1 3.5 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGF82374.1 - 0.96 9.2 14.9 7.3 6.4 0.2 5.5 5 1 1 6 6 6 0 TPR repeat WD40 PF00400.32 EGF82375.1 - 2.2e-15 56.8 0.4 0.019 15.8 0.1 6.1 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT_2 PF13646.6 EGF82375.1 - 6e-06 26.6 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 EGF82375.1 - 0.00047 20.2 0.0 0.83 10.1 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat MMS22L_C PF14911.6 EGF82375.1 - 0.0042 16.2 0.1 0.0091 15.1 0.1 1.4 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal DUF3385 PF11865.8 EGF82375.1 - 0.15 11.9 1.1 24 4.8 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) CRF1 PF10380.9 EGF82375.1 - 0.92 9.9 6.7 1.5 9.2 0.6 3.4 3 0 0 3 3 3 0 Transcription factor CRF1 Rhodanese PF00581.20 EGF82376.1 - 1.7e-27 96.1 0.0 3e-13 50.2 0.0 2.3 2 1 0 2 2 2 2 Rhodanese-like domain Hexokinase_2 PF03727.16 EGF82377.1 - 2.4e-84 282.5 0.0 3.8e-84 281.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGF82377.1 - 3.2e-69 232.8 0.0 4.5e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0183 PF03676.14 EGF82378.1 - 6.3e-93 312.2 0.0 7.4e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) DUF5132 PF17195.4 EGF82378.1 - 0.055 13.6 0.0 0.48 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Clathrin_lg_ch PF01086.17 EGF82379.1 - 5.4e-36 124.8 0.4 6e-35 121.4 0.4 2.1 1 1 0 1 1 1 1 Clathrin light chain UPF0565 PF10561.9 EGF82379.1 - 0.015 14.5 0.2 0.02 14.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Virulence_fact PF13769.6 EGF82379.1 - 0.14 12.4 0.8 0.28 11.5 0.8 1.4 1 0 0 1 1 1 0 Virulence factor RhoGAP PF00620.27 EGF82380.1 - 3e-40 137.5 0.0 5.2e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PQQ_3 PF13570.6 EGF82381.1 - 3.4e-09 36.9 0.3 0.017 15.6 0.1 3.7 3 0 0 3 3 3 2 PQQ-like domain WD40 PF00400.32 EGF82381.1 - 8.2e-08 32.8 19.4 0.03 15.2 1.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 EGF82381.1 - 3.7e-06 26.5 0.6 1.6e-05 24.4 0.3 1.9 2 0 0 2 2 2 1 WD40-like domain F-box-like PF12937.7 EGF82381.1 - 7.9e-06 25.7 0.1 2.4e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EGF82381.1 - 0.00028 20.6 0.0 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 EGF82381.1 - 0.0065 15.2 0.3 0.78 8.3 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin Nup120/160 SAP PF02037.27 EGF82381.1 - 0.032 14.0 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 SAP domain Mito_carr PF00153.27 EGF82382.1 - 1.5e-64 214.0 2.7 6.7e-23 80.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGF82382.1 - 6e-13 49.0 0.9 4.2e-08 33.5 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF82382.1 - 3.7e-11 41.8 0.2 0.0017 17.8 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGF82382.1 - 3.8e-10 38.9 0.1 0.092 12.7 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EGF82382.1 - 2.4e-05 24.1 0.6 0.38 10.6 0.1 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_10 PF14788.6 EGF82382.1 - 6.3e-05 22.7 0.7 0.001 18.9 0.0 2.8 2 1 1 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGF82382.1 - 0.00014 21.1 0.7 0.62 9.7 0.0 3.9 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EGF82382.1 - 0.00021 21.6 0.1 0.0097 16.2 0.1 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Zwilch PF09817.9 EGF82383.1 - 6.8e-11 41.3 5.0 4e-10 38.8 2.5 2.7 2 1 0 2 2 2 1 RZZ complex, subunit zwilch Sec1 PF00995.23 EGF82384.1 - 3.2e-17 63.0 1.2 5.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Sec1 family ABC_membrane PF00664.23 EGF82385.1 - 4.8e-70 236.3 32.4 3.3e-35 122.1 12.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF82385.1 - 6.5e-53 178.9 0.5 1.3e-29 103.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF82385.1 - 2.4e-09 36.9 6.6 0.0025 17.3 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF82385.1 - 2.3e-08 34.1 4.7 0.0016 18.5 0.7 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF82385.1 - 4.5e-07 29.9 4.2 0.00022 21.1 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGF82385.1 - 4.9e-07 29.4 0.2 0.055 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGF82385.1 - 2.6e-06 27.5 0.6 0.079 12.8 0.1 3.5 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGF82385.1 - 7.3e-06 26.5 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGF82385.1 - 3.3e-05 24.5 0.3 0.36 11.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGF82385.1 - 3.4e-05 23.4 0.6 0.22 11.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 EGF82385.1 - 8.4e-05 22.7 11.8 0.0017 18.4 2.7 2.8 3 0 0 3 3 2 2 Dynamin family T2SSE PF00437.20 EGF82385.1 - 0.00013 21.1 0.3 0.45 9.5 0.4 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGF82385.1 - 0.00034 20.1 0.3 0.87 8.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 EGF82385.1 - 0.00069 19.4 0.1 1.9 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGF82385.1 - 0.001 19.3 1.2 1.2 9.4 0.1 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGF82385.1 - 0.0011 18.3 1.1 0.16 11.2 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 EGF82385.1 - 0.0019 17.2 0.8 0.83 8.6 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EGF82385.1 - 0.003 17.7 4.3 0.14 12.2 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 EGF82385.1 - 0.0031 16.5 0.5 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain IIGP PF05049.13 EGF82385.1 - 0.0042 16.2 1.5 0.58 9.2 0.2 2.2 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.7 EGF82385.1 - 0.0049 15.8 1.0 0.63 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_15 PF13175.6 EGF82385.1 - 0.0053 16.5 0.8 2.2 7.9 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 EGF82385.1 - 0.0055 16.0 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain Roc PF08477.13 EGF82385.1 - 0.0061 16.8 1.3 3.6 7.8 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EGF82385.1 - 0.0076 15.9 3.4 0.32 10.5 0.3 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGF82385.1 - 0.0083 16.1 0.6 1.2 9.0 0.1 2.4 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EGF82385.1 - 0.017 14.4 0.9 4.7 6.3 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 EGF82385.1 - 0.023 13.8 1.8 3.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGF82385.1 - 0.025 15.1 0.8 7 7.2 0.4 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF82385.1 - 0.031 14.7 0.6 9.7 6.6 0.1 2.9 3 0 0 3 3 2 0 RNA helicase FeoB_N PF02421.18 EGF82385.1 - 0.032 13.8 0.2 0.61 9.6 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 EGF82385.1 - 0.038 13.7 0.2 10 5.8 0.0 2.9 4 0 0 4 4 2 0 IstB-like ATP binding protein TsaE PF02367.17 EGF82385.1 - 0.047 13.7 0.1 8.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EGF82385.1 - 0.056 13.2 0.1 8.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 EGF82385.1 - 0.13 12.1 1.1 6.1 6.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2244 PF10003.9 EGF82385.1 - 0.14 11.8 1.5 2.5 7.7 1.4 2.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) ATPase_2 PF01637.18 EGF82385.1 - 0.17 11.8 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 EGF82385.1 - 0.2 10.9 0.8 9.7 5.4 0.1 2.2 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 EGF82385.1 - 0.22 11.3 2.3 5.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 EGF82385.1 - 0.28 10.5 2.2 10 5.4 0.2 2.7 2 0 0 2 2 2 0 AIG1 family AMPK1_CBM PF16561.5 EGF82386.1 - 2e-16 59.9 0.2 4.6e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SH3_1 PF00018.28 EGF82386.1 - 3.6e-09 36.1 0.0 6.9e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 SH3 domain CBM_48 PF02922.18 EGF82386.1 - 1.1e-05 25.7 0.2 4.8e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SH3_9 PF14604.6 EGF82386.1 - 1.8e-05 24.5 0.0 6.1e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF82386.1 - 2.8e-05 23.7 0.0 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Helicase_C_2 PF13307.6 EGF82388.1 - 3.2e-54 183.7 0.0 8.2e-54 182.3 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGF82388.1 - 1.2e-42 145.6 2.2 2.5e-42 144.5 2.2 1.6 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EGF82388.1 - 0.00062 19.8 0.0 0.004 17.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF82388.1 - 0.0084 15.9 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase HBB PF06777.11 EGF82388.1 - 0.033 13.9 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain DFP PF04127.15 EGF82392.1 - 0.18 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Actin PF00022.19 EGF82393.1 - 1.2e-133 445.7 0.0 4.8e-133 443.7 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 EGF82393.1 - 0.052 13.5 0.4 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Spore germination GerD central core domain Vps8 PF12816.7 EGF82394.1 - 2.1e-51 174.3 3.5 2.1e-51 174.3 3.5 3.0 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGF82394.1 - 0.003 17.4 0.5 0.043 13.7 0.2 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-rbx1 PF12678.7 EGF82394.1 - 0.0061 16.8 1.4 0.017 15.4 1.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGF82394.1 - 0.0099 15.8 1.1 0.023 14.6 1.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGF82394.1 - 0.01 15.6 1.9 0.017 15.0 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF82394.1 - 0.011 16.0 1.8 0.033 14.5 1.8 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 EGF82394.1 - 0.24 11.2 2.8 0.16 11.8 0.2 2.1 2 0 0 2 2 2 0 RING-like zinc finger GATase PF00117.28 EGF82395.1 - 2.7e-13 50.1 0.0 3.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGF82395.1 - 0.0001 22.2 0.4 0.00038 20.3 0.4 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EGF82395.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain HTS PF04204.16 EGF82395.1 - 0.012 14.6 0.1 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 Homoserine O-succinyltransferase DJ-1_PfpI PF01965.24 EGF82395.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Katanin_con80 PF13925.6 EGF82396.1 - 2.5e-42 144.6 0.5 4.5e-42 143.8 0.5 1.4 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 EGF82396.1 - 6.7e-31 105.9 25.1 4.2e-09 36.9 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82396.1 - 3.5e-15 56.1 0.0 0.0013 18.9 0.0 5.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF82396.1 - 7.7e-07 29.2 0.0 0.059 13.2 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGF82396.1 - 0.0028 17.0 0.0 0.14 11.5 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain WD40 PF00400.32 EGF82397.1 - 1.3e-39 133.4 15.3 1.1e-06 29.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82397.1 - 1.3e-12 47.8 0.7 0.021 15.1 0.0 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF82397.1 - 0.0016 17.5 0.0 0.063 12.2 0.0 2.8 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Bromodomain PF00439.25 EGF82398.1 - 2.3e-23 82.1 2.0 6.6e-23 80.6 0.1 2.7 3 0 0 3 3 3 1 Bromodomain Peptidase_M1 PF01433.20 EGF82398.1 - 5.9e-08 32.5 1.0 2.2e-07 30.7 1.0 2.0 1 1 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 EGF82398.1 - 1.4e-05 25.4 0.0 0.15 12.5 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats IF-2B PF01008.17 EGF82400.1 - 2.5e-59 200.8 0.1 2.9e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TSC22 PF01166.18 EGF82401.1 - 0.035 14.4 0.3 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family tRNA-synt_2c PF01411.19 EGF82402.1 - 3.1e-217 722.5 0.0 4e-217 722.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGF82402.1 - 5e-17 61.7 0.1 1.4e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGF82402.1 - 6.7e-14 52.5 4.4 1.6e-13 51.3 4.4 1.7 1 0 0 1 1 1 1 DHHA1 domain betaPIX_CC PF16523.5 EGF82402.1 - 0.2 11.5 4.4 8.9 6.2 0.2 3.5 4 0 0 4 4 4 0 betaPIX coiled coil Linker_histone PF00538.19 EGF82403.1 - 1.4e-24 86.2 0.0 1.4e-24 86.2 0.0 4.3 2 1 2 5 5 5 1 linker histone H1 and H5 family Actin PF00022.19 EGF82404.1 - 7.2e-125 416.8 0.0 2.9e-124 414.8 0.0 1.7 1 1 0 1 1 1 1 Actin ANAPC5 PF12862.7 EGF82405.1 - 4.4e-18 65.1 1.2 6.4e-15 55.0 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EGF82405.1 - 0.005 17.1 11.6 0.039 14.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82405.1 - 0.059 13.2 1.8 3.2 7.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat FlbT PF07378.11 EGF82405.1 - 0.086 12.9 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FlbT WD40 PF00400.32 EGF82406.1 - 7.1e-37 124.8 23.3 1.3e-06 29.0 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82406.1 - 7.6e-17 61.4 0.6 0.0015 18.8 0.2 5.5 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF82406.1 - 3.1e-05 22.9 2.0 0.34 9.5 0.1 4.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGF82406.1 - 3.1e-05 23.1 4.7 0.2 10.5 3.1 4.6 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGF82406.1 - 3.6e-05 23.7 0.6 0.0098 15.8 0.0 3.3 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF4142 PF13628.6 EGF82406.1 - 0.017 15.3 2.5 0.017 15.3 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) zf-C4H2 PF10146.9 EGF82406.1 - 0.023 15.0 7.0 0.039 14.3 7.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein FapA PF03961.13 EGF82406.1 - 0.58 8.7 7.6 0.9 8.1 7.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 EGF82406.1 - 0.84 8.5 4.4 1.3 7.9 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 EGF82406.1 - 2.7 8.2 7.0 6 7.0 7.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 EGF82406.1 - 5.1 7.2 9.3 50 4.0 9.0 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 EGF82406.1 - 9.8 6.9 7.3 6.9 7.4 2.9 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Aminotran_1_2 PF00155.21 EGF82407.1 - 1.3e-39 136.4 0.0 1.7e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGF82407.1 - 0.00034 19.3 0.0 0.0005 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGF82407.1 - 0.17 11.1 0.0 0.89 8.8 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase Rootletin PF15035.6 EGF82408.1 - 0.0057 16.7 12.8 0.0057 16.7 12.8 1.8 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.18 EGF82408.1 - 0.023 15.0 3.2 0.28 11.5 0.1 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family APG6_N PF17675.1 EGF82408.1 - 0.34 11.4 13.0 0.73 10.4 10.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Shugoshin_N PF07558.11 EGF82408.1 - 0.45 10.4 4.6 9.4 6.2 0.3 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 EGF82408.1 - 3.1 8.5 10.1 11 6.7 4.8 2.9 2 0 0 2 2 2 0 SlyX Spc7 PF08317.11 EGF82408.1 - 3.3 6.5 17.4 0.25 10.2 12.6 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 EGF82408.1 - 4.4 5.7 8.3 7.3 5.0 8.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cep57_CLD_2 PF14197.6 EGF82408.1 - 7.1 6.8 11.8 1.6 8.9 5.8 2.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 EGF82408.1 - 9.8 4.0 10.6 2.9 5.7 6.3 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cellulase PF00150.18 EGF82409.1 - 1.2e-17 64.3 0.1 5.4e-10 39.2 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGF82409.1 - 1.6e-08 35.0 0.1 5.6e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Thiolase_N PF00108.23 EGF82410.1 - 1.1e-90 303.5 0.2 1.6e-90 303.0 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF82410.1 - 2.2e-45 153.2 0.7 6e-45 151.9 0.7 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGF82410.1 - 0.0024 17.5 0.1 0.0054 16.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EGF82410.1 - 0.0099 14.6 0.1 0.021 13.5 0.1 1.5 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Transgly PF00912.22 EGF82410.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase Dodecin PF07311.12 EGF82410.1 - 0.16 12.2 0.3 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 Dodecin ACP_syn_III PF08545.10 EGF82410.1 - 4.6 7.2 6.1 6.5 6.7 0.8 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CAP_N PF01213.19 EGF82411.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Kelch_5 PF13854.6 EGF82414.1 - 4.2e-07 29.8 5.5 0.034 14.1 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EGF82414.1 - 3.8e-06 26.4 12.6 0.011 15.3 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EGF82414.1 - 6.8e-06 26.2 11.6 0.76 10.2 0.1 6.3 6 1 1 7 7 7 3 Kelch motif EGF_2 PF07974.13 EGF82414.1 - 5e-05 23.6 13.4 5e-05 23.6 13.4 2.8 2 0 0 2 2 2 1 EGF-like domain Kelch_4 PF13418.6 EGF82414.1 - 0.00034 20.6 14.2 2.2 8.4 0.1 6.6 5 1 1 6 6 6 1 Galactose oxidase, central domain CUB PF00431.20 EGF82414.1 - 0.00045 20.5 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 CUB domain EB PF01683.18 EGF82414.1 - 0.0062 16.8 2.5 0.0062 16.8 2.5 2.4 2 0 0 2 2 2 1 EB module Methyltransf_31 PF13847.6 EGF82414.1 - 0.14 12.0 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Kelch_3 PF13415.6 EGF82414.1 - 0.15 12.4 20.1 2.1 8.7 0.3 5.9 5 1 0 5 5 5 0 Galactose oxidase, central domain MRP-S28 PF10213.9 EGF82415.1 - 5e-21 75.4 0.0 2.2e-20 73.3 0.0 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal subunit protein CTP_synth_N PF06418.14 EGF82416.1 - 4e-126 419.7 0.0 5.5e-126 419.3 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGF82416.1 - 7.6e-57 192.2 0.0 1.3e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGF82416.1 - 0.0002 21.2 0.0 0.00063 19.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 Transket_pyr PF02779.24 EGF82416.1 - 0.017 14.8 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain Abhydrolase_1 PF00561.20 EGF82417.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF82417.1 - 1.6e-07 32.2 0.0 2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF82417.1 - 0.057 12.7 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DSPc PF00782.20 EGF82419.1 - 6e-06 26.1 0.0 6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF82419.1 - 0.0045 16.6 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase UQ_con PF00179.26 EGF82420.1 - 4.8e-15 55.4 0.1 7e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glu_syn_central PF04898.14 EGF82420.1 - 0.009 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate synthase central domain zf_C2H2_10 PF18414.1 EGF82420.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger SET PF00856.28 EGF82421.1 - 2.9e-10 40.8 0.0 7.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EGF82421.1 - 3.8e-09 37.3 0.1 7.2e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding DUF505 PF04458.12 EGF82421.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) TTL PF03133.15 EGF82422.1 - 1.2e-91 307.0 1.3 1.4e-91 306.7 1.3 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGF82422.1 - 1.6e-07 30.9 0.0 1.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGF82422.1 - 1.2e-05 24.7 0.0 0.00096 18.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Cnd2 PF05786.14 EGF82423.1 - 7.5e-134 448.2 11.1 7.5e-133 444.9 11.1 2.1 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGF82423.1 - 0.021 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAM110_N PF14161.6 EGF82424.1 - 1.7 8.9 5.3 1.4 9.2 0.7 3.0 3 0 0 3 3 3 0 Centrosome-associated N terminus Fez1 PF06818.15 EGF82424.1 - 2 8.8 73.2 4.9 7.6 15.3 5.4 1 1 4 5 5 5 0 Fez1 Filament PF00038.21 EGF82424.1 - 3 7.4 72.2 0.0094 15.6 36.7 3.5 2 1 1 3 3 3 0 Intermediate filament protein GHMP_kinases_N PF00288.26 EGF82425.1 - 3.6e-08 33.5 0.0 8.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGF82425.1 - 2.5e-06 27.8 0.0 1.9e-05 25.0 0.0 2.4 3 0 0 3 3 3 1 GHMP kinases C terminal Peptidase_S41 PF03572.18 EGF82426.1 - 7e-11 42.0 0.0 1.3e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 DEAD PF00270.29 EGF82428.1 - 7.4e-48 162.6 0.0 2.2e-47 161.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF82428.1 - 3.7e-37 127.1 0.1 1.4e-30 105.8 0.1 3.4 2 1 1 3 3 3 3 Helicase conserved C-terminal domain ResIII PF04851.15 EGF82428.1 - 2.2e-06 27.8 0.0 1.3e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGF82428.1 - 7e-05 22.2 0.0 0.00017 20.9 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGF82428.1 - 0.026 13.8 3.2 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Trigger_N PF05697.13 EGF82428.1 - 0.032 14.6 1.5 0.093 13.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) UTP25 PF06862.12 EGF82428.1 - 0.044 12.6 0.1 0.2 10.4 0.1 2.1 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cyt-b5 PF00173.28 EGF82429.1 - 2.4e-10 40.4 0.0 4.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ran_BP1 PF00638.18 EGF82430.1 - 1.5e-18 67.3 0.1 2.4e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 EGF82430.1 - 7.1e-13 49.0 0.7 7.1e-13 49.0 0.7 3.1 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) HEPN_AbiU2 PF18734.1 EGF82430.1 - 0.17 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 AbiU2 Cys_Met_Meta_PP PF01053.20 EGF82431.1 - 2e-149 497.3 0.0 2.2e-149 497.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGF82431.1 - 5.2e-06 25.9 0.1 6.9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGF82431.1 - 7.2e-05 22.3 1.8 0.00027 20.4 1.8 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGF82431.1 - 0.0011 18.0 0.2 0.0041 16.1 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V MOZ_SAS PF01853.18 EGF82432.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-CCCH_4 PF18044.1 EGF82433.1 - 1e-14 53.9 29.5 1.1e-06 28.3 3.8 4.6 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGF82433.1 - 4.3e-12 45.7 32.3 0.00097 19.1 2.5 5.1 4 1 0 4 4 4 4 Zinc finger domain Torus PF16131.5 EGF82433.1 - 2.9e-11 44.0 14.7 0.003 18.2 0.0 4.3 3 1 1 4 4 4 3 Torus domain zf-CCCH PF00642.24 EGF82433.1 - 7.5e-11 41.7 28.7 0.0011 18.8 0.5 4.7 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGF82433.1 - 1.1e-07 32.1 1.3 1.1e-07 32.1 1.3 3.2 3 0 0 3 3 3 1 Zinc-finger containing family zf-RING_2 PF13639.6 EGF82433.1 - 2.2e-06 27.9 9.5 2.2e-06 27.9 9.5 4.1 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 EGF82433.1 - 7.3e-06 25.8 6.5 7.3e-06 25.8 6.5 3.5 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF82433.1 - 1.4e-05 24.8 7.8 1.4e-05 24.8 7.8 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 EGF82433.1 - 0.00014 22.2 30.3 0.0067 16.9 3.9 4.9 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 EGF82433.1 - 0.0008 19.2 7.2 0.0008 19.2 7.2 4.3 5 1 0 5 5 5 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGF82433.1 - 0.0055 16.7 7.8 0.0055 16.7 7.8 2.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGF82433.1 - 1.5 9.1 16.6 0.079 13.1 7.4 3.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SMK-1 PF04802.15 EGF82434.1 - 5.2e-68 228.7 9.7 3.8e-67 225.8 10.9 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 EGF82434.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 WH1 domain DUF4604 PF15377.6 EGF82435.1 - 1e-19 71.7 12.8 4e-19 69.7 12.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) G_glu_transpept PF01019.21 EGF82436.1 - 1.7e-172 574.8 0.0 1.9e-172 574.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Med1 PF10744.9 EGF82437.1 - 3.7e-28 98.7 0.5 6.3e-28 98.0 0.5 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 ABC2_membrane PF01061.24 EGF82438.1 - 5.5e-52 176.2 47.2 2.6e-34 118.5 20.2 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGF82438.1 - 7.2e-51 172.3 0.0 1.7e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGF82438.1 - 8.3e-11 42.2 0.4 0.0013 18.6 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGF82438.1 - 9.3e-09 35.4 1.7 0.00076 19.4 0.4 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGF82438.1 - 1.4e-07 31.2 2.1 0.0054 16.4 0.5 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGF82438.1 - 1.3e-06 28.9 0.1 0.0065 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EGF82438.1 - 4.8e-06 26.9 2.5 0.046 14.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGF82438.1 - 1.1e-05 25.8 1.5 0.04 14.2 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGF82438.1 - 3.3e-05 23.5 0.1 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGF82438.1 - 5e-05 23.1 0.6 0.33 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGF82438.1 - 9e-05 22.8 1.0 0.73 10.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGF82438.1 - 0.0001 22.3 0.4 0.64 10.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGF82438.1 - 0.00013 22.5 0.5 0.25 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGF82438.1 - 0.00014 22.4 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGF82438.1 - 0.00017 21.5 1.7 0.021 14.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EGF82438.1 - 0.00075 19.9 0.5 0.51 10.7 0.0 3.2 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 EGF82438.1 - 0.00077 19.2 0.1 0.5 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGF82438.1 - 0.0014 18.1 0.2 0.54 9.7 0.1 3.3 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain CbiA PF01656.23 EGF82438.1 - 0.0044 17.1 0.0 0.45 10.6 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EGF82438.1 - 0.0051 17.0 0.2 1.1 9.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGF82438.1 - 0.0077 15.5 0.1 0.54 9.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.18 EGF82438.1 - 0.0099 15.3 1.4 1.2 8.5 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF2075 PF09848.9 EGF82438.1 - 0.011 15.1 0.3 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 EGF82438.1 - 0.011 15.6 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 EGF82438.1 - 0.012 15.3 0.3 0.098 12.4 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 EGF82438.1 - 0.013 15.4 1.8 0.25 11.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EGF82438.1 - 0.015 14.9 0.9 0.71 9.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EGF82438.1 - 0.018 15.0 1.4 0.19 11.6 0.1 2.6 3 0 0 3 3 2 0 NTPase T2SSE PF00437.20 EGF82438.1 - 0.018 14.1 1.9 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 EGF82438.1 - 0.02 14.6 1.3 2.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EGF82438.1 - 0.033 14.2 0.0 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGF82438.1 - 0.061 13.4 3.9 5.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EGF82438.1 - 0.062 13.0 0.0 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EGF82438.1 - 0.093 11.6 0.8 0.82 8.5 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Ploopntkinase3 PF18751.1 EGF82438.1 - 0.1 12.5 0.3 12 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SRPRB PF09439.10 EGF82438.1 - 0.11 12.0 0.4 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATPase PF06745.13 EGF82438.1 - 0.11 11.8 0.7 11 5.3 0.1 2.4 2 0 0 2 2 2 0 KaiC AAA PF00004.29 EGF82438.1 - 0.16 12.4 0.1 20 5.6 0.0 3.1 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGF82438.1 - 0.17 11.1 0.2 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 EGF82438.1 - 0.19 12.2 0.1 26 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGF82438.1 - 0.2 11.9 0.6 17 5.7 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EGF82438.1 - 0.21 11.6 0.3 0.98 9.4 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DnaB_C PF03796.15 EGF82438.1 - 0.23 10.7 1.3 12 5.2 0.1 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 EGF82438.1 - 1.4 8.5 3.4 0.86 9.2 0.3 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4234 PF14018.6 EGF82438.1 - 5.2 7.3 9.2 0.095 12.8 0.3 2.9 3 0 0 3 3 1 0 Domain of unknown function (DUF4234) DUF4246 PF14033.6 EGF82439.1 - 1.2e-97 327.9 0.1 2.7e-97 326.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) Arm PF00514.23 EGF82439.1 - 0.029 14.4 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat MF_alpha_N PF05436.11 EGF82440.1 - 0.023 14.6 0.2 0.093 12.6 0.1 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus AAA PF00004.29 EGF82441.1 - 8.6e-18 65.0 0.0 1.9e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 EGF82441.1 - 5.7e-06 25.7 0.1 1.8e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF815 PF05673.13 EGF82441.1 - 0.00053 19.2 0.2 0.0019 17.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGF82441.1 - 0.0029 17.7 0.4 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGF82441.1 - 0.0082 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGF82441.1 - 0.0097 15.4 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGF82441.1 - 0.013 15.1 0.3 0.35 10.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EGF82441.1 - 0.026 14.8 0.2 0.38 11.0 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF82441.1 - 0.027 14.8 0.2 0.13 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EGF82441.1 - 0.052 13.8 1.4 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF82441.1 - 0.069 13.5 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EGF82441.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IF3_C PF00707.22 EGF82442.1 - 1.1e-09 38.2 0.6 2e-09 37.3 0.6 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EGF82442.1 - 9.9e-06 25.7 0.2 2.1e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain MRP-S25 PF13741.6 EGF82442.1 - 0.11 12.1 2.9 0.11 12.0 1.7 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S25 Ncstrn_small PF18266.1 EGF82443.1 - 1.4e-37 129.3 0.0 3.3e-37 128.1 0.0 1.7 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 EGF82443.1 - 2.2e-36 125.5 2.8 1.1e-35 123.2 2.8 1.9 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 EGF82443.1 - 0.00013 21.7 0.1 0.00028 20.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M28 UQ_con PF00179.26 EGF82444.1 - 2.2e-40 137.5 0.0 2.6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SNAP PF14938.6 EGF82446.1 - 1.7e-104 349.2 10.2 1.9e-104 349.1 10.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EGF82446.1 - 8.7e-05 22.3 3.9 1.5 9.0 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82446.1 - 0.00016 21.9 5.4 0.21 11.9 1.0 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82446.1 - 0.00016 21.6 7.9 0.43 10.9 0.4 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF82446.1 - 0.0026 18.3 8.1 3.3 8.5 0.0 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82446.1 - 0.0043 16.8 7.6 2.1 8.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82446.1 - 0.0067 16.5 9.2 3 8.2 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 EGF82446.1 - 0.0072 15.5 4.7 0.03 13.4 4.7 1.9 1 1 0 1 1 1 1 Spatacsin C-terminus RPN7 PF10602.9 EGF82446.1 - 0.056 13.1 1.7 0.09 12.5 0.9 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 DHR-2 PF06920.13 EGF82446.1 - 0.09 11.4 0.3 0.16 10.6 0.2 1.4 1 1 0 1 1 1 0 Dock homology region 2 MIT PF04212.18 EGF82446.1 - 0.096 12.8 9.4 4.1 7.5 0.0 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EGF82446.1 - 0.13 13.0 5.6 1.7 9.3 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82446.1 - 0.15 12.0 5.8 44 4.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82446.1 - 0.38 11.7 10.0 1.1 10.2 0.0 4.6 3 1 1 5 5 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGF82446.1 - 1 9.0 5.8 3 7.5 5.6 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) NSF PF02071.20 EGF82446.1 - 6.2 8.1 13.7 55 5.2 0.3 6.0 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat Y_phosphatase2 PF03162.13 EGF82447.1 - 7.4e-58 194.8 0.0 8e-58 194.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGF82447.1 - 6.1e-06 26.4 0.0 7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family TMV_coat PF00721.21 EGF82447.1 - 0.0018 18.1 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Virus coat protein (TMV like) DSPc PF00782.20 EGF82447.1 - 0.0077 16.1 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF82447.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L9_C PF03948.14 EGF82447.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain Exo5 PF09810.9 EGF82450.1 - 0.00091 18.8 1.4 0.0011 18.5 1.4 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease DivIC PF04977.15 EGF82450.1 - 0.02 14.7 6.6 0.021 14.6 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Exonuc_VII_L PF02601.15 EGF82450.1 - 0.081 12.5 1.6 0.1 12.2 1.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RPA_interact_C PF14768.6 EGF82450.1 - 0.22 12.1 0.5 0.57 10.8 0.2 1.9 1 1 1 2 2 2 0 Replication protein A interacting C-terminal SlyX PF04102.12 EGF82450.1 - 0.37 11.4 1.9 4 8.1 0.1 2.3 2 0 0 2 2 2 0 SlyX DUF3395 PF11875.8 EGF82450.1 - 0.71 9.7 4.6 0.31 10.9 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) DUF3837 PF12939.7 EGF82450.1 - 1.4 9.3 4.8 5.5 7.4 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) Spc24 PF08286.11 EGF82450.1 - 2 8.7 6.8 8.3 6.7 1.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TRAPP PF04051.16 EGF82452.1 - 3.6e-36 124.1 0.0 4.3e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF111 PF01969.17 EGF82452.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 FAS_N PF17828.1 EGF82453.1 - 0.13 12.3 1.5 17 5.4 0.0 3.9 5 0 0 5 5 5 0 N-terminal domain in fatty acid synthase subunit beta Tubulin PF00091.25 EGF82455.1 - 3.1e-68 229.9 0.0 5.6e-68 229.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF82455.1 - 1.9e-41 141.2 0.5 2.8e-41 140.6 0.5 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGF82455.1 - 9.6e-05 22.7 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGF82455.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain RSN1_7TM PF02714.15 EGF82456.1 - 2.4e-59 200.9 24.0 2.4e-59 200.9 24.0 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGF82456.1 - 4.6e-30 105.2 0.0 7.6e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGF82456.1 - 3.6e-20 72.3 0.1 1.5e-14 54.1 0.0 3.0 1 1 1 2 2 2 2 Late exocytosis, associated with Golgi transport SWIRM PF04433.17 EGF82457.1 - 2.7e-15 56.5 0.0 6.9e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EGF82457.1 - 1.5e-11 44.3 0.3 4.1e-11 42.9 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain JAB PF01398.21 EGF82457.1 - 7.9e-09 35.5 0.0 2.4e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGF82457.1 - 3.2e-08 33.4 0.2 1.5e-06 28.0 0.2 3.0 2 1 1 3 3 3 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 EGF82457.1 - 0.00014 22.0 0.6 0.00047 20.3 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 EGF82457.1 - 0.025 14.6 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 SLIDE Plasmodium_Vir PF05795.11 EGF82458.1 - 0.29 10.5 0.0 0.34 10.3 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PDEase_I PF00233.19 EGF82460.1 - 1.2e-83 280.5 0.3 1.2e-83 280.5 0.3 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 EGF82460.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DNA_methylase PF00145.17 EGF82461.1 - 8.5e-39 133.8 0.0 1.7e-38 132.9 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase XPG_N PF00752.17 EGF82461.1 - 0.087 13.3 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 0 XPG N-terminal domain zf-rbx1 PF12678.7 EGF82462.1 - 2.5e-06 27.7 8.9 6.2e-06 26.4 8.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGF82462.1 - 1e-05 25.8 14.4 0.00021 21.6 14.4 2.5 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGF82462.1 - 2.6e-05 24.2 3.4 2.6e-05 24.2 3.4 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4201 PF13870.6 EGF82462.1 - 0.00079 19.2 22.4 0.047 13.4 5.4 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) zf-RING_11 PF17123.5 EGF82462.1 - 0.0011 18.6 6.9 0.0016 18.1 2.4 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF82462.1 - 0.0027 17.6 10.7 0.016 15.1 10.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF82462.1 - 0.0046 16.9 8.4 0.012 15.5 8.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGF82462.1 - 0.0092 15.8 7.5 0.0092 15.8 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 EGF82462.1 - 0.024 14.7 18.9 0.79 9.7 1.1 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1726 PF08351.11 EGF82462.1 - 0.17 11.9 0.4 5.8 6.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Zn_ribbon_17 PF17120.5 EGF82462.1 - 0.35 10.5 8.7 0.075 12.7 5.0 1.8 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EGF82462.1 - 0.61 10.2 9.9 1.8 8.7 8.6 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-NADH-PPase PF09297.11 EGF82462.1 - 0.78 9.4 3.3 0.48 10.1 0.5 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_3 PF13920.6 EGF82462.1 - 0.8 9.6 10.9 0.44 10.4 7.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGF82462.1 - 1.1 9.5 8.4 13 6.1 8.4 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3450 PF11932.8 EGF82462.1 - 1.9 7.7 16.0 5.9 6.1 6.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) zf-RING_4 PF14570.6 EGF82462.1 - 2.1 8.2 4.7 5.5 6.9 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGF82462.1 - 2.5 8.0 5.7 1 9.2 3.0 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EGF82462.1 - 3.2 8.1 7.5 11 6.5 7.5 1.9 1 0 0 1 1 1 0 RING-like domain GIT_CC PF16559.5 EGF82462.1 - 5.2 7.0 8.8 0.96 9.4 0.3 3.9 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor KxDL PF10241.9 EGF82462.1 - 5.8 7.3 16.0 0.36 11.1 2.1 3.8 1 1 2 3 3 3 0 Uncharacterized conserved protein Fez1 PF06818.15 EGF82462.1 - 9.8 6.6 22.5 12 6.3 7.1 2.8 1 1 1 2 2 2 0 Fez1 PCI PF01399.27 EGF82463.1 - 1.7e-14 54.2 1.2 2.8e-14 53.5 0.3 1.8 2 1 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EGF82463.1 - 2.4e-11 43.1 0.2 5.2e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DDHD PF02862.17 EGF82464.1 - 2.2e-24 86.9 19.5 5.8e-22 79.0 14.9 3.7 2 1 0 2 2 2 1 DDHD domain PGAP1 PF07819.13 EGF82464.1 - 0.039 13.7 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Tyrosinase PF00264.20 EGF82465.1 - 4.2e-20 73.0 9.9 7e-10 39.6 1.5 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase RRM_1 PF00076.22 EGF82466.1 - 2.6e-77 254.6 0.0 2.7e-20 71.9 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EGF82466.1 - 6.6e-06 26.0 0.0 0.13 12.0 0.0 3.6 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EGF82466.1 - 0.00014 21.7 0.0 0.85 9.5 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif DbpA PF03880.15 EGF82466.1 - 0.0014 18.6 0.1 0.62 10.1 0.0 3.7 4 0 0 4 4 4 1 DbpA RNA binding domain RRM_7 PF16367.5 EGF82466.1 - 0.002 18.2 0.2 3.7 7.7 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 EGF82466.1 - 0.0064 16.1 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGF82466.1 - 0.052 13.6 0.8 3.6 7.7 0.0 3.4 5 0 0 5 5 5 0 Limkain b1 Arm PF00514.23 EGF82467.1 - 0.00033 20.6 10.1 5.3 7.2 0.0 6.3 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat RNase_HII PF01351.18 EGF82467.1 - 0.014 15.2 0.4 0.052 13.4 0.2 1.9 2 0 0 2 2 2 0 Ribonuclease HII HEAT_EZ PF13513.6 EGF82467.1 - 0.11 13.0 0.1 0.87 10.2 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat Pyr_redox_2 PF07992.14 EGF82468.1 - 4.7e-22 78.6 0.4 1e-21 77.5 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF82468.1 - 1.6e-08 35.0 2.3 4.3e-07 30.4 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGF82468.1 - 0.00021 20.6 1.7 0.00049 19.5 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGF82468.1 - 0.0038 17.4 1.5 3.9 7.8 0.1 3.0 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGF82468.1 - 0.0085 15.4 2.4 2 7.6 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EGF82468.1 - 0.013 14.4 1.5 0.31 9.8 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.18 EGF82468.1 - 0.019 15.2 2.3 4.3 7.6 0.1 2.9 3 1 0 3 3 3 0 TrkA-N domain K_oxygenase PF13434.6 EGF82468.1 - 0.028 13.6 0.5 0.27 10.3 0.2 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_S9 PF00326.21 EGF82468.1 - 0.16 11.4 4.2 0.26 10.7 0.2 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family HNH_2 PF13391.6 EGF82469.1 - 5.3e-05 23.3 0.2 0.0027 17.8 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease Cytochrome_C7 PF14522.6 EGF82469.1 - 0.049 13.6 2.2 1.1 9.3 0.6 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c HNH PF01844.23 EGF82469.1 - 0.12 12.6 1.7 1.6 9.0 1.7 2.6 1 1 0 1 1 1 0 HNH endonuclease Paired_CXXCH_1 PF09699.10 EGF82469.1 - 0.24 11.1 4.5 2.7 7.8 0.2 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) HNH_2 PF13391.6 EGF82470.1 - 0.00013 22.0 0.2 0.0048 17.0 0.1 2.7 2 0 0 2 2 2 1 HNH endonuclease Cytochrome_C7 PF14522.6 EGF82470.1 - 0.23 11.5 3.5 1.9 8.6 0.6 2.6 1 1 2 3 3 3 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF82470.1 - 0.76 9.6 4.8 4.1 7.2 0.2 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Arm-DNA-bind_4 PF14657.6 EGF82471.1 - 0.029 14.1 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain DUF3422 PF11902.8 EGF82471.1 - 0.092 11.8 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF4372 PF14294.6 EGF82471.1 - 0.12 12.6 1.4 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) ANTH PF07651.16 EGF82472.1 - 1.9e-46 158.3 0.4 1.9e-46 158.3 0.4 1.5 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EGF82472.1 - 6.3e-06 26.2 0.1 1.3e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Tim44 PF04280.15 EGF82474.1 - 0.019 15.1 0.0 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 Tim44-like domain MscL PF01741.18 EGF82475.1 - 1.6e-31 109.2 1.7 2.1e-31 108.7 1.7 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF3330 PF11809.8 EGF82475.1 - 0.015 15.3 4.8 0.031 14.3 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) UPF0547 PF10571.9 EGF82475.1 - 1.2 9.3 6.4 3.3 7.9 6.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 MscL PF01741.18 EGF82476.1 - 9.2e-29 100.2 0.3 1.4e-28 99.6 0.3 1.3 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 EGF82476.1 - 0.0083 16.1 1.5 0.02 14.9 0.7 1.9 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGF82476.1 - 0.039 14.7 0.8 0.082 13.7 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon family zf-RING_4 PF14570.6 EGF82476.1 - 0.043 13.6 1.3 0.095 12.5 1.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DNA_ligase_ZBD PF03119.16 EGF82476.1 - 0.045 13.8 2.9 2.7 8.1 0.4 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Pkinase PF00069.25 EGF82478.1 - 2.9e-67 226.8 0.0 5.1e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82478.1 - 2.9e-36 125.1 0.0 5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82478.1 - 5.3e-06 26.0 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGF82478.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EGF82478.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_Mig-6 PF11555.8 EGF82478.1 - 0.76 9.9 4.7 0.93 9.6 0.1 2.8 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Pkinase PF00069.25 EGF82479.1 - 1.2e-67 228.1 0.0 1.3e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82479.1 - 7.5e-39 133.6 0.0 1e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82479.1 - 5.2e-09 35.8 0.0 9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGF82479.1 - 0.0017 17.4 0.1 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Inhibitor_Mig-6 PF11555.8 EGF82479.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Kdo PF06293.14 EGF82479.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF82479.1 - 0.13 12.2 0.0 4.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_tranf_2_3 PF13641.6 EGF82480.1 - 8.5e-28 97.8 0.1 1.2e-27 97.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF82480.1 - 2.1e-10 40.3 0.5 1.2e-09 37.8 0.5 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF82480.1 - 5.2e-09 36.1 0.0 9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EGF82480.1 - 0.0013 18.6 6.9 0.0013 18.6 6.9 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Phosphoesterase PF04185.14 EGF82481.1 - 4.4e-34 118.2 4.1 1.3e-33 116.7 2.2 2.3 1 1 1 2 2 2 1 Phosphoesterase family PsaM PF07465.13 EGF82482.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) CMAS PF02353.20 EGF82483.1 - 4.1e-67 226.4 1.0 5.1e-67 226.0 1.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGF82483.1 - 1.1e-12 48.0 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF82483.1 - 3.2e-11 43.7 0.0 6.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF82483.1 - 4.6e-11 43.3 0.0 9.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF82483.1 - 7.1e-07 29.9 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF82483.1 - 1.4e-06 28.2 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF82483.1 - 3e-05 23.6 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGF82483.1 - 7.8e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGF82483.1 - 0.00043 20.3 0.0 0.003 17.5 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain DOT1 PF08123.13 EGF82483.1 - 0.0017 17.9 0.0 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Met_10 PF02475.16 EGF82483.1 - 0.0023 17.7 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EGF82483.1 - 0.013 15.2 0.2 0.055 13.1 0.2 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 EGF82483.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 EGF82483.1 - 0.015 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EGF82483.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 EGF82483.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGF82483.1 - 0.21 11.3 0.1 0.51 10.1 0.0 1.7 2 0 0 2 2 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.32 EGF82484.1 - 1.6e-36 123.6 25.2 2.3e-07 31.4 0.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82484.1 - 6.4e-09 36.0 6.2 0.55 10.6 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF82484.1 - 6.8e-08 31.6 7.0 0.64 8.6 0.0 4.9 2 2 3 5 5 5 4 Nucleoporin Nup120/160 DUF1513 PF07433.11 EGF82484.1 - 0.0084 15.2 0.2 2.1 7.4 0.1 3.1 1 1 4 5 5 5 3 Protein of unknown function (DUF1513) Frtz PF11768.8 EGF82484.1 - 0.097 11.0 1.1 3 6.1 0.1 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 EGF82484.1 - 0.17 10.6 8.5 3.8 6.2 0.1 3.8 1 1 3 4 4 4 0 Nup133 N terminal like EF-hand_1 PF00036.32 EGF82485.1 - 6.5e-18 62.9 0.7 3.4e-05 23.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGF82485.1 - 2.8e-17 62.9 2.4 4.4e-11 43.1 0.3 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGF82485.1 - 8.3e-16 56.5 2.2 6e-05 22.7 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGF82485.1 - 2.3e-08 33.2 1.4 0.0074 15.7 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGF82485.1 - 1.5e-05 24.7 4.1 0.0017 18.1 0.5 3.9 2 1 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGF82485.1 - 0.00038 20.7 0.0 0.0097 16.2 0.0 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGF82485.1 - 0.0072 16.3 2.1 6.2 6.8 0.1 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGF82485.1 - 0.02 15.1 1.3 0.054 13.7 1.3 1.7 1 1 0 1 1 1 0 Dockerin type I domain FOXO-TAD PF16676.5 EGF82485.1 - 0.094 13.1 0.4 1.4 9.4 0.2 2.8 3 0 0 3 3 3 0 Transactivation domain of FOXO protein family DUF2985 PF11204.8 EGF82486.1 - 2.1e-12 47.0 4.7 4.1e-12 46.1 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sarcoglycan_1 PF04790.13 EGF82486.1 - 0.077 12.3 1.1 0.29 10.5 0.3 2.0 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein DUF1688 PF07958.11 EGF82488.1 - 1.6e-156 521.3 0.0 1.8e-156 521.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Choline_sulf_C PF12411.8 EGF82488.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal TMEM135_C_rich PF15982.5 EGF82489.1 - 4.3e-05 24.1 0.3 4.3e-05 24.1 0.3 1.9 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 EGF82489.1 - 0.00052 20.4 1.8 0.0091 16.4 1.5 2.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family TMEM154 PF15102.6 EGF82490.1 - 2.2e-05 24.4 1.2 4.5e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 TMEM154 protein family Alpha_GJ PF03229.13 EGF82490.1 - 0.002 18.7 0.2 0.002 18.7 0.2 2.8 3 0 0 3 3 3 1 Alphavirus glycoprotein J SCF PF02404.15 EGF82490.1 - 0.018 14.4 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor DUF3188 PF11384.8 EGF82490.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) LapA_dom PF06305.11 EGF82490.1 - 0.097 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_M56 PF05569.11 EGF82490.1 - 0.2 10.8 0.1 0.32 10.1 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Nucleos_tra2_C PF07662.13 EGF82491.1 - 5.4e-64 215.8 7.2 5.4e-64 215.8 7.2 2.3 2 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EGF82491.1 - 1e-20 74.1 4.1 1e-20 74.1 4.1 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EGF82491.1 - 0.021 15.1 7.7 0.021 15.1 7.7 3.1 3 1 0 3 3 3 0 Nucleoside recognition Skp1_POZ PF03931.15 EGF82492.1 - 1.2e-20 73.4 0.7 2.1e-20 72.7 0.7 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 EGF82492.1 - 0.00094 19.2 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain MIP PF00230.20 EGF82493.1 - 1.5e-24 87.0 10.7 3e-15 56.5 1.2 2.9 2 1 0 2 2 2 2 Major intrinsic protein WD40 PF00400.32 EGF82494.1 - 1.5e-12 47.8 0.2 7.4e-09 36.1 0.1 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82494.1 - 0.00019 21.6 0.1 0.039 14.3 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain LPD7 PF18821.1 EGF82494.1 - 0.091 12.9 0.1 0.3 11.2 0.0 1.7 1 1 0 2 2 2 0 Large polyvalent protein-associated domain 7 Fungal_trans PF04082.18 EGF82495.1 - 1.2e-12 47.5 0.3 1.2e-12 47.5 0.3 3.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain CDT1_C PF16679.5 EGF82495.1 - 0.41 11.1 2.0 2 8.9 1.3 2.4 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain HAT_KAT11 PF08214.11 EGF82496.1 - 1.3e-20 74.0 0.0 2.4e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein Cyt-b5 PF00173.28 EGF82497.1 - 1.4e-07 31.5 0.0 3.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SH3_9 PF14604.6 EGF82497.1 - 2.1e-06 27.5 0.0 5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF82497.1 - 7.7e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Cytochrom_B561 PF03188.16 EGF82497.1 - 7.8e-06 26.1 10.7 7.8e-06 26.1 10.7 2.7 2 1 1 3 3 3 2 Eukaryotic cytochrome b561 FAD_binding_6 PF00970.24 EGF82497.1 - 0.00019 21.8 0.0 0.00069 19.9 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SH3_2 PF07653.17 EGF82497.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF2427 PF10348.9 EGF82497.1 - 0.14 12.0 11.1 0.12 12.2 7.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) RIO1 PF01163.22 EGF82498.1 - 4.5e-73 244.9 0.6 4.5e-73 244.9 0.6 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGF82498.1 - 3.8e-05 23.7 0.0 0.051 13.5 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGF82498.1 - 0.0032 16.9 0.7 0.18 11.1 0.0 2.7 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 EGF82498.1 - 0.0072 14.7 12.2 0.0082 14.5 12.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Lectin_N PF03954.14 EGF82498.1 - 0.21 11.4 2.0 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain S1-P1_nuclease PF02265.16 EGF82500.1 - 3.2e-37 128.7 0.4 3.7e-37 128.5 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease GTP_CH_N PF12471.8 EGF82501.1 - 1.9e-89 298.5 0.0 2.9e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EGF82501.1 - 3.2e-16 59.4 0.0 4.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II PT-HINT PF07591.11 EGF82501.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain Ribosomal_S24e PF01282.19 EGF82502.1 - 1.4e-36 124.3 0.2 1.4e-36 124.3 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e E1-E2_ATPase PF00122.20 EGF82503.1 - 1.1e-46 158.6 3.9 1.7e-45 154.8 1.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGF82503.1 - 1.3e-18 66.8 0.0 2.8e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EGF82503.1 - 3e-18 66.2 13.2 5.9e-15 55.4 8.6 3.3 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGF82503.1 - 3.8e-18 66.6 0.0 7.5e-10 39.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF82503.1 - 2.9e-15 55.7 0.0 8.4e-15 54.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF82503.1 - 0.0023 17.7 0.4 0.067 12.9 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGF82503.1 - 0.091 13.2 0.3 3.6 8.0 0.1 3.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1129 PF06570.11 EGF82503.1 - 7.4 6.0 7.9 7.6 6.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) CRAL_TRIO PF00650.20 EGF82504.1 - 4.5e-11 42.7 0.0 7.6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain UQ_con PF00179.26 EGF82505.1 - 1.1e-19 70.5 0.0 1.7e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGF82505.1 - 0.048 14.0 0.1 0.084 13.2 0.1 1.5 1 1 0 1 1 1 0 RWD domain DUF4695 PF15766.5 EGF82505.1 - 0.091 13.0 1.7 0.14 12.4 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Clr5 PF14420.6 EGF82505.1 - 0.13 12.6 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Clr5 domain CSN8_PSD8_EIF3K PF10075.9 EGF82506.1 - 5.7e-08 32.9 0.2 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 CSN8/PSMD8/EIF3K family PCI PF01399.27 EGF82506.1 - 1.2e-05 25.7 0.0 2.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PCI domain Per1 PF04080.13 EGF82507.1 - 5e-95 318.1 17.3 6e-95 317.8 17.3 1.1 1 0 0 1 1 1 1 Per1-like family Peptidase_M36 PF02128.15 EGF82508.1 - 6.6e-156 519.1 2.1 8.4e-156 518.8 2.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF82508.1 - 6.4e-05 22.7 1.3 0.00017 21.4 1.3 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif VCX_VCY PF15231.6 EGF82508.1 - 0.016 15.9 1.0 0.029 15.1 1.0 1.3 1 0 0 1 1 1 0 Variable charge X/Y family Lyx_isomer PF07385.12 EGF82508.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 D-lyxose isomerase YabA PF06156.13 EGF82509.1 - 0.053 14.2 0.5 0.053 14.2 0.5 3.4 4 0 0 4 4 4 0 Initiation control protein YabA MutS_IV PF05190.18 EGF82509.1 - 0.19 12.1 10.4 0.24 11.8 0.5 2.8 2 0 0 2 2 2 0 MutS family domain IV COG6 PF06419.11 EGF82509.1 - 1.4 7.0 19.0 0.017 13.3 5.6 2.3 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Baculo_PEP_C PF04513.12 EGF82509.1 - 2.5 8.1 7.1 0.14 12.2 1.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hormone_1 PF00103.20 EGF82509.1 - 3.4 7.4 9.2 0.25 11.1 1.7 2.3 2 0 0 2 2 2 0 Somatotropin hormone family DUF4140 PF13600.6 EGF82509.1 - 5.1 7.6 8.9 10 6.6 4.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec20 PF03908.13 EGF82509.1 - 8.5 6.4 13.6 4.6 7.2 5.4 2.8 2 0 0 2 2 2 0 Sec20 DUF4246 PF14033.6 EGF82511.1 - 1e-64 219.3 0.0 1.4e-44 153.0 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) Arm PF00514.23 EGF82511.1 - 0.023 14.7 0.0 0.19 11.8 0.0 2.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Sox_N PF12444.8 EGF82512.1 - 0.029 15.5 0.2 0.06 14.5 0.2 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal SlyX PF04102.12 EGF82513.1 - 0.13 12.9 0.9 1.3 9.7 0.2 2.2 1 1 0 2 2 2 0 SlyX DUF3368 PF11848.8 EGF82513.1 - 0.2 11.5 0.6 0.99 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Peptidase_S41 PF03572.18 EGF82514.1 - 3.2e-10 39.8 0.0 6.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 AAA_16 PF13191.6 EGF82515.1 - 0.00034 21.0 0.0 0.00088 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF82515.1 - 0.011 16.0 0.1 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGF82515.1 - 0.083 13.2 0.3 0.64 10.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain DUF4246 PF14033.6 EGF82516.1 - 7e-95 318.8 0.0 1.1e-94 318.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arm PF00514.23 EGF82516.1 - 0.0015 18.5 0.0 0.0098 15.9 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGF82516.1 - 0.0088 14.6 0.1 0.014 14.0 0.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region PAT1 PF09770.9 EGF82517.1 - 4.6 5.4 29.8 7.8 4.6 29.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OsmC PF02566.19 EGF82519.1 - 8e-15 55.1 0.0 1.1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Mito_carr PF00153.27 EGF82520.1 - 1.1e-44 150.3 3.4 1.2e-24 86.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1129 PF06570.11 EGF82520.1 - 0.19 11.2 2.7 3.9 6.9 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Pyridoxal_deC PF00282.19 EGF82521.1 - 2e-42 145.3 0.0 4.2e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGF82521.1 - 6e-08 32.0 0.1 1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGF82521.1 - 3.6e-05 23.2 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EGF82521.1 - 0.06 12.0 0.0 0.12 11.0 0.0 1.5 1 1 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS TPR_5 PF12688.7 EGF82521.1 - 0.11 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat Arf PF00025.21 EGF82522.1 - 1.8e-65 219.7 0.0 2e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGF82522.1 - 6e-10 38.8 0.0 1.1e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGF82522.1 - 9e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGF82522.1 - 1.1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGF82522.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGF82522.1 - 3.7e-06 27.1 0.0 1.1e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGF82522.1 - 3.5e-05 23.3 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 EGF82522.1 - 0.0083 15.7 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EGF82522.1 - 0.0087 15.6 0.1 0.062 12.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Slu7 PF11708.8 EGF82523.1 - 1.3e-107 359.6 15.5 1.3e-107 359.6 15.5 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGF82523.1 - 0.091 12.5 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF702 PF05142.12 EGF82523.1 - 1.8 9.0 5.9 0.47 10.9 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DAO PF01266.24 EGF82524.1 - 7.9e-53 180.3 0.0 8.9e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGF82524.1 - 1e-05 25.6 0.1 2.8e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGF82524.1 - 0.014 14.5 0.1 0.031 13.4 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGF82524.1 - 0.062 13.3 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGF82524.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EGF82524.1 - 0.083 12.3 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.12 EGF82524.1 - 0.083 11.9 0.0 0.47 9.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.6 EGF82524.1 - 0.14 11.3 0.0 3.6 6.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Sacchrp_dh_NADP PF03435.18 EGF82524.1 - 0.16 12.2 0.2 1.2 9.3 0.1 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Cyclin_N PF00134.23 EGF82525.1 - 2.9e-47 159.6 1.4 2.6e-44 150.0 1.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGF82525.1 - 2.1e-37 127.9 0.1 4.2e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain TPR_2 PF07719.17 EGF82526.1 - 8.5e-08 31.7 0.9 0.0018 18.2 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82526.1 - 1.7e-06 27.6 0.1 0.0012 18.6 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82526.1 - 4.6e-06 27.2 0.5 1.1e-05 26.0 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF82526.1 - 1.8e-05 24.8 0.8 3.5e-05 23.9 0.8 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82526.1 - 0.00014 21.4 0.0 0.0083 15.8 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 EGF82526.1 - 0.018 15.8 1.6 1.4 9.9 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82526.1 - 0.025 14.8 0.0 4 7.9 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82526.1 - 0.034 14.5 0.1 0.12 12.9 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82526.1 - 0.036 13.9 0.1 0.68 9.9 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 EGF82526.1 - 1.1 8.1 14.1 0.38 9.6 0.4 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 zf-MYND PF01753.18 EGF82527.1 - 3.9e-10 39.6 11.6 7.4e-10 38.8 11.6 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EGF82527.1 - 0.011 16.9 2.4 0.024 15.8 2.4 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-Mss51 PF13824.6 EGF82527.1 - 0.67 10.1 3.2 1.6 8.8 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EGF82527.1 - 1.4 9.2 11.7 3.7 7.9 11.7 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EGF82527.1 - 5.6 6.9 9.3 15 5.6 9.3 1.8 1 0 0 1 1 1 0 HIT zinc finger KdpC PF02669.15 EGF82528.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 K+-transporting ATPase, c chain DUF4704 PF15787.5 EGF82529.1 - 5.3e-21 75.1 5.3 4.3e-20 72.1 0.8 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 EGF82529.1 - 1.5e-05 25.2 0.8 3.2e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Beach PF02138.18 EGF82530.1 - 1.2e-126 421.7 0.0 1.8e-126 421.2 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGF82530.1 - 1.3e-15 57.3 0.1 3e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 EGF82530.1 - 2.5e-15 56.5 3.7 3.7e-15 55.9 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 EGF82530.1 - 3.6e-10 40.3 5.6 4e-05 24.3 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1088 PF06469.11 EGF82530.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Arginosuc_synth PF00764.19 EGF82531.1 - 6.3e-163 542.6 0.0 7.5e-163 542.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGF82531.1 - 0.00068 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGF82531.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Lipase_3 PF01764.25 EGF82532.1 - 1.2e-28 99.7 0.0 2.9e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 EGF82532.1 - 0.00018 21.2 2.3 0.051 13.1 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGF82532.1 - 0.00029 20.2 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EGF82532.1 - 0.00039 20.0 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EGF82532.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EGF82532.1 - 0.029 14.0 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Putative esterase La PF05383.17 EGF82533.1 - 6.9e-17 61.2 0.0 1.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 La domain RRP7 PF12923.7 EGF82533.1 - 0.063 13.4 0.2 0.44 10.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Lipase_3 PF01764.25 EGF82535.1 - 5.2e-31 107.4 0.0 7.9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGF82535.1 - 0.01 15.4 0.3 0.11 12.1 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGF82535.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGF82535.1 - 0.054 13.2 0.2 0.25 11.1 0.1 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EGF82535.1 - 0.086 13.4 0.0 0.086 13.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGF82535.1 - 0.095 12.4 0.2 0.25 11.0 0.0 1.8 2 1 0 2 2 2 0 PGAP1-like protein Chitin_synth_2 PF03142.15 EGF82537.1 - 1.3e-234 779.7 1.2 1.9e-234 779.1 1.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGF82537.1 - 6.3e-69 232.9 0.0 3.1e-68 230.6 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EGF82537.1 - 2.8e-19 68.8 0.1 1.1e-18 66.9 0.4 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 EGF82537.1 - 8.6e-14 52.0 0.1 2.2e-11 44.1 0.0 3.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF82537.1 - 3.1e-12 46.8 5.8 8.9e-12 45.3 4.6 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGF82537.1 - 4.4e-05 23.4 0.0 0.0021 17.9 0.0 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGF82537.1 - 0.0039 16.7 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 21 Myosin_head PF00063.21 EGF82539.1 - 9.7e-71 238.9 0.0 4e-67 226.9 0.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) Chitin_synth_2 PF03142.15 EGF82539.1 - 5.7e-47 160.5 0.0 8.7e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EGF82539.1 - 4.6e-08 33.1 0.9 6.4e-05 23.0 0.0 3.4 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Chitin_synth_2 PF03142.15 EGF82540.1 - 1.4e-165 552.0 4.9 1.6e-165 551.7 4.9 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGF82540.1 - 4.9e-12 46.2 0.0 8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGF82540.1 - 6.3e-10 39.3 9.5 2.8e-09 37.2 9.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGF82540.1 - 0.007 15.9 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF82540.1 - 0.01 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 QslA_E PF18226.1 EGF82540.1 - 0.17 11.8 0.0 5 7.1 0.0 2.3 2 0 0 2 2 2 0 LasR-specific antiactivator QslA chain E Hydrolase_4 PF12146.8 EGF82541.1 - 4.9e-12 45.6 0.1 5.1e-11 42.3 0.0 1.9 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF82541.1 - 5.4e-05 23.9 0.3 7.7e-05 23.4 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGF82541.1 - 0.00041 19.9 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGF82541.1 - 0.00055 19.7 0.1 0.00079 19.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 EGF82541.1 - 0.086 12.0 0.0 0.42 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) MSP1a PF11670.8 EGF82542.1 - 0.046 13.0 4.8 0.1 11.8 4.8 1.5 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Peptidase_M36 PF02128.15 EGF82543.1 - 0.093 11.9 0.0 0.8 8.8 0.0 2.3 1 1 2 3 3 3 0 Fungalysin metallopeptidase (M36) BCDHK_Adom3 PF10436.9 EGF82544.1 - 4.7e-59 198.8 0.0 6.1e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGF82544.1 - 1.1e-11 45.3 0.0 1.9e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGF82544.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ShK PF01549.24 EGF82544.1 - 0.57 10.8 2.4 2.4 8.8 0.1 2.3 2 0 0 2 2 2 0 ShK domain-like Pkinase PF00069.25 EGF82545.1 - 7.5e-69 232.0 0.0 8.5e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82545.1 - 3.8e-38 131.3 0.0 4.4e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF82545.1 - 1.5e-07 30.7 0.2 2.1e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF82545.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGF82545.1 - 0.0001 22.0 0.2 0.00016 21.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF82545.1 - 0.0029 17.0 0.8 0.0041 16.5 0.8 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGF82545.1 - 0.0032 17.1 0.5 0.36 10.4 0.3 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 EGF82545.1 - 0.0032 17.4 0.4 0.0091 15.9 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF82545.1 - 0.098 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase AAA_33 PF13671.6 EGF82546.1 - 3.1e-05 24.2 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF82546.1 - 4.9e-05 23.8 0.0 7.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.14 EGF82546.1 - 0.00026 20.9 0.1 0.0097 15.8 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EGF82546.1 - 0.00027 21.5 0.1 0.00061 20.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 EGF82546.1 - 0.00028 21.3 0.0 0.0005 20.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGF82546.1 - 0.00034 20.9 0.0 0.00057 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EGF82546.1 - 0.00054 19.6 0.0 0.0009 18.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EGF82546.1 - 0.00089 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EGF82546.1 - 0.001 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EGF82546.1 - 0.0012 18.7 0.1 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 EGF82546.1 - 0.0028 18.0 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EGF82546.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.6 EGF82546.1 - 0.0039 17.2 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGF82546.1 - 0.0042 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGF82546.1 - 0.0059 17.1 0.1 0.018 15.6 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EGF82546.1 - 0.0069 15.9 0.1 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGF82546.1 - 0.0072 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGF82546.1 - 0.0082 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EGF82546.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGF82546.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGF82546.1 - 0.013 14.8 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.15 EGF82546.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 EGF82546.1 - 0.023 13.7 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 EGF82546.1 - 0.026 14.5 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EGF82546.1 - 0.035 14.0 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA12 PF10443.9 EGF82546.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DUF815 PF05673.13 EGF82546.1 - 0.039 13.1 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGF82546.1 - 0.048 14.0 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGF82546.1 - 0.085 12.6 0.1 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 EGF82546.1 - 0.097 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGF82546.1 - 0.097 12.4 0.1 0.42 10.3 0.0 2.1 2 1 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 EGF82546.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase dNK PF01712.19 EGF82546.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 EGF82546.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGF82546.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGF82546.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase RRP7 PF12923.7 EGF82547.1 - 1.1e-35 122.4 4.9 1.7e-35 121.7 4.9 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EGF82547.1 - 1.4e-11 44.5 1.2 5.5e-10 39.3 0.1 3.3 2 2 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 EGF82547.1 - 0.0028 17.4 0.0 0.077 12.8 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_E_G PF10150.9 EGF82547.1 - 0.048 13.1 0.2 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease E/G family AAA_23 PF13476.6 EGF82547.1 - 0.067 13.7 1.7 0.11 13.0 1.7 1.3 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EGF82547.1 - 0.26 10.6 2.4 0.34 10.2 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDK PF00334.19 EGF82548.1 - 2.7e-48 163.4 0.0 2.8e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 EGF82548.1 - 0.0059 16.4 0.6 0.018 14.9 0.6 1.8 1 1 0 1 1 1 1 DUF1126 PH-like domain Usp PF00582.26 EGF82549.1 - 4.2e-25 88.9 0.0 5.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Apq12 PF12716.7 EGF82550.1 - 0.014 15.3 8.0 0.014 15.3 8.0 2.0 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis BRI3BP PF14965.6 EGF82550.1 - 0.092 12.3 6.0 0.12 11.9 6.0 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 RNB PF00773.19 EGF82552.1 - 1.3e-95 320.5 0.0 2.4e-95 319.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EGF82552.1 - 9.3e-19 67.2 0.0 1.9e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EGF82552.1 - 2.3e-08 34.2 0.1 7.2e-08 32.7 0.1 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 EGF82552.1 - 7.5e-06 25.7 0.1 2.2e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Rrp44-like cold shock domain RB_A PF01858.17 EGF82552.1 - 0.12 12.2 0.0 0.47 10.2 0.0 2.0 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain AdoHcyase PF05221.17 EGF82553.1 - 1.1e-133 445.1 0.0 8.1e-74 248.4 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGF82553.1 - 1.5e-86 288.5 3.1 2.1e-86 288.0 3.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGF82553.1 - 1.8e-09 37.2 0.2 3.9e-09 36.1 0.2 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGF82553.1 - 1e-05 25.2 0.1 1.7e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGF82553.1 - 0.013 15.7 0.2 0.04 14.2 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain TMEM107 PF14995.6 EGF82553.1 - 0.053 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein THF_DHG_CYH_C PF02882.19 EGF82553.1 - 0.11 11.9 0.8 0.45 9.8 0.7 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ribosomal_S17 PF00366.20 EGF82554.1 - 7.2e-26 90.1 0.6 1.2e-25 89.4 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 EGF82554.1 - 8.4e-24 83.7 0.6 2e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ints3 PF10189.9 EGF82555.1 - 6.2e-69 231.7 0.8 6.2e-69 231.7 0.8 2.3 2 0 0 2 2 2 1 Integrator complex subunit 3 tRNA_lig_CPD PF08302.11 EGF82555.1 - 0.08 12.4 1.2 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain Got1 PF04178.12 EGF82556.1 - 1.9e-32 112.1 18.6 2.2e-32 111.8 18.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Pam16 PF03656.13 EGF82557.1 - 4.5e-34 117.2 1.3 4.9e-34 117.1 1.3 1.0 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EGF82557.1 - 0.038 14.1 0.1 0.072 13.2 0.1 1.5 1 1 0 1 1 1 0 DnaJ domain DUF2802 PF10975.8 EGF82557.1 - 0.073 13.2 0.7 0.2 11.8 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) CppA_C PF14507.6 EGF82557.1 - 0.087 13.6 0.1 0.26 12.0 0.0 1.7 1 1 1 2 2 2 0 CppA C-terminal ThiF PF00899.21 EGF82558.1 - 1.5e-17 63.8 0.0 2.8e-17 62.9 0.0 1.4 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EGF82558.1 - 0.0039 17.3 0.0 6.5 7.0 0.0 3.8 4 0 0 4 4 4 2 Ubiquitin-activating enzyme E1 four-helix bundle NusG_add PF18298.1 EGF82558.1 - 0.064 13.5 0.1 3.9 7.7 0.1 2.4 2 0 0 2 2 2 0 NusG additional domain Prok-TraM PF09228.10 EGF82558.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Noc2 PF03715.13 EGF82559.1 - 7.5e-111 370.1 2.2 1.4e-110 369.3 2.2 1.4 1 0 0 1 1 1 1 Noc2p family RPGR1_C PF18111.1 EGF82560.1 - 2.9e-17 63.1 1.8 1.1e-16 61.2 0.0 2.6 3 0 0 3 3 3 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2-C2_1 PF11618.8 EGF82560.1 - 1.2e-06 28.7 1.4 0.004 17.2 0.1 4.5 3 1 1 4 4 4 2 First C2 domain of RPGR-interacting protein 1 Cyt-b5 PF00173.28 EGF82561.1 - 2.6e-19 69.1 2.1 2.4e-18 66.1 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGF82561.1 - 3.3e-13 50.1 13.1 3.3e-13 50.1 13.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1744 PF08490.12 EGF82562.1 - 2.1e-131 438.2 0.1 3.6e-131 437.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGF82562.1 - 1.6e-60 205.0 0.1 2.9e-60 204.2 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGF82562.1 - 3.9e-13 48.9 0.2 6.2e-12 45.0 0.1 2.4 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGF82562.1 - 2.6e-05 24.0 0.1 6.9e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGF82562.1 - 0.0004 20.4 0.0 0.0013 18.8 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily zf-CHY PF05495.12 EGF82562.1 - 0.13 12.7 6.2 0.048 14.2 1.9 2.5 2 0 0 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 EGF82562.1 - 0.14 12.6 1.4 0.41 11.1 1.4 1.8 1 0 0 1 1 1 0 Cytochrome c3 HypA PF01155.19 EGF82562.1 - 0.22 11.6 0.9 0.61 10.1 0.9 1.8 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 EGF82562.1 - 2 9.2 7.5 6.4 7.6 7.5 2.0 1 0 0 1 1 1 0 zinc-ribbon family DPBB_1 PF03330.18 EGF82563.1 - 0.02 15.1 0.1 0.027 14.8 0.1 1.3 1 1 0 1 1 1 0 Lytic transglycolase KilA-N PF04383.13 EGF82564.1 - 2.6e-05 24.0 0.0 0.0055 16.5 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Rcd1 PF04078.13 EGF82565.1 - 1.8e-126 420.8 2.6 2e-126 420.6 2.6 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pigment_DH PF06324.11 EGF82565.1 - 0.18 12.0 0.3 0.44 10.7 0.3 1.7 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) zf-C2H2 PF00096.26 EGF82566.1 - 1.2e-16 60.1 19.5 7.6e-06 26.1 1.1 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF82566.1 - 2.2e-13 49.8 16.0 0.00024 21.7 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF82566.1 - 8.6e-11 41.8 20.1 1.2e-06 28.6 2.2 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGF82566.1 - 8e-07 29.2 7.0 0.1 12.9 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGF82566.1 - 0.0001 22.6 11.8 0.4 11.1 0.0 3.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EGF82566.1 - 0.0023 17.8 4.7 0.28 11.2 1.7 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 EGF82566.1 - 0.0033 17.7 6.8 0.0099 16.2 6.6 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 EGF82566.1 - 0.0075 16.4 2.5 0.0075 16.4 2.5 2.2 2 1 0 2 2 2 1 Zinc ribbon domain zf-C2HE PF16278.5 EGF82566.1 - 0.018 15.5 8.8 2.7 8.5 0.5 3.2 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_SprT PF17283.2 EGF82566.1 - 0.022 14.6 8.0 0.39 10.7 0.2 2.9 2 2 1 3 3 3 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 EGF82566.1 - 0.038 13.6 3.2 0.39 10.3 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 EGF82566.1 - 0.041 13.6 13.3 0.63 9.9 0.4 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type FYDLN_acid PF09538.10 EGF82566.1 - 0.072 13.8 1.2 0.16 12.6 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-C2H2_12 PF18112.1 EGF82566.1 - 0.089 13.3 2.1 17 6.0 0.0 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_9 PF14369.6 EGF82566.1 - 0.094 13.0 4.1 0.59 10.4 4.1 2.3 1 1 1 2 2 2 0 zinc-ribbon zf-C2H2_6 PF13912.6 EGF82566.1 - 0.094 12.7 11.3 0.12 12.4 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger NOA36 PF06524.12 EGF82566.1 - 0.094 12.0 3.4 0.095 12.0 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein HypA PF01155.19 EGF82566.1 - 0.14 12.2 0.9 0.17 11.9 0.9 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L37ae PF01780.19 EGF82566.1 - 0.17 12.0 2.6 0.41 10.7 0.2 2.2 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-trcl PF13451.6 EGF82566.1 - 0.34 10.9 2.6 3 7.8 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain C1_4 PF07975.12 EGF82566.1 - 0.34 11.2 4.0 0.96 9.7 4.0 1.8 1 1 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_2 PF12756.7 EGF82566.1 - 0.45 10.9 8.9 4.8 7.6 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) C5HCH PF17982.1 EGF82566.1 - 0.75 10.0 8.3 0.36 11.0 1.1 2.6 1 1 0 2 2 2 0 NSD Cys-His rich domain Zn_Tnp_IS1595 PF12760.7 EGF82566.1 - 0.77 9.8 5.3 3.2 7.8 0.6 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HNH PF01844.23 EGF82566.1 - 2.7 8.3 7.1 22 5.3 0.1 3.1 3 0 0 3 3 3 0 HNH endonuclease zf-H2C2_5 PF13909.6 EGF82566.1 - 3.6 7.4 12.8 26 4.7 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Synaptobrevin PF00957.21 EGF82567.1 - 1.6e-30 104.7 1.0 2.2e-30 104.3 1.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGF82567.1 - 1.5e-21 76.2 0.1 2.4e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tex_N PF09371.10 EGF82567.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Myc_N PF01056.18 EGF82568.1 - 0.021 14.7 13.6 0.028 14.3 13.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3136 PF11334.8 EGF82568.1 - 0.036 13.8 0.1 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) DALR_1 PF05746.15 EGF82568.1 - 0.17 12.1 7.9 3.1 8.0 0.1 2.5 2 0 0 2 2 2 0 DALR anticodon binding domain MRP-S32 PF10210.9 EGF82568.1 - 0.77 10.4 10.3 1.7 9.3 3.7 2.5 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 DUF5427 PF10310.9 EGF82568.1 - 1.6 7.6 22.4 2.1 7.2 22.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PPP4R2 PF09184.11 EGF82568.1 - 2 7.9 23.8 2.4 7.7 23.8 1.2 1 0 0 1 1 1 0 PPP4R2 Peptidase_S64 PF08192.11 EGF82568.1 - 2.9 6.3 20.2 3.4 6.0 20.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3381 PF11861.8 EGF82568.1 - 4.5 7.1 27.9 1.7 8.4 19.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF2201_N PF13203.6 EGF82568.1 - 4.9 6.7 11.1 9.2 5.8 11.1 1.6 1 1 0 1 1 1 0 Putative metallopeptidase domain NOA36 PF06524.12 EGF82568.1 - 7.8 5.7 21.0 14 4.9 20.9 1.5 1 1 0 1 1 1 0 NOA36 protein Spc7 PF08317.11 EGF82569.1 - 0.017 14.0 0.4 0.022 13.7 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 EGF82569.1 - 0.18 12.3 2.8 2.6 8.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 HJURP_C PF12347.8 EGF82572.1 - 0.082 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat TAF1_subA PF14929.6 EGF82573.1 - 0.011 15.2 0.2 0.011 15.2 0.2 1.5 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A TMF_TATA_bd PF12325.8 EGF82574.1 - 0.00031 21.0 1.2 0.088 13.0 0.0 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding NYD-SP28_assoc PF14775.6 EGF82574.1 - 0.13 12.4 1.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain G-patch PF01585.23 EGF82576.1 - 4.9e-17 61.6 0.5 8.4e-17 60.8 0.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF82576.1 - 4.1e-10 39.6 0.4 2.4e-09 37.1 0.2 2.2 2 0 0 2 2 2 1 G-patch domain Asp PF00026.23 EGF82577.1 - 3.3e-17 62.9 0.4 4.6e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82577.1 - 1.3e-08 34.8 0.1 8.3e-08 32.2 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal eIF-3_zeta PF05091.12 EGF82579.1 - 4e-135 451.8 0.0 4.4e-135 451.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EGF82579.1 - 0.12 11.9 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RPN1_RPN2_N PF17781.1 EGF82580.1 - 1.3e-120 402.5 0.2 2.3e-120 401.7 0.1 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGF82580.1 - 4.2e-31 106.8 0.0 8.4e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGF82580.1 - 2.5e-21 74.9 19.9 0.00016 21.9 0.1 7.7 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGF82580.1 - 4e-06 27.1 1.9 0.051 14.0 0.0 4.6 3 1 1 4 4 4 3 HEAT repeats DUF2776 PF10951.8 EGF82580.1 - 0.015 14.6 0.1 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) LSM PF01423.22 EGF82581.1 - 4.7e-19 67.8 0.4 5e-19 67.8 0.4 1.0 1 0 0 1 1 1 1 LSM domain DEAD PF00270.29 EGF82582.1 - 1.9e-31 109.2 0.0 4.9e-31 107.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF82582.1 - 3.3e-23 82.1 2.6 3.7e-19 69.1 0.0 3.7 3 2 1 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGF82582.1 - 8.7e-07 29.1 2.0 0.053 13.5 0.0 3.4 2 1 0 3 3 3 2 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGF82582.1 - 8.6e-05 21.4 0.0 0.00018 20.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EGF82582.1 - 0.0065 16.8 0.0 4.7 7.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Asp PF00026.23 EGF82583.1 - 1.6e-10 40.9 0.1 2.8e-10 40.1 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82583.1 - 0.0037 17.0 0.1 0.032 14.0 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Glyco_tran_WecB PF03808.13 EGF82585.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF4246 PF14033.6 EGF82586.1 - 1.2e-28 100.5 0.0 1.5e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Retrotran_gag_2 PF14223.6 EGF82587.1 - 1.3e-08 34.6 1.1 2.2e-08 33.9 1.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pkinase PF00069.25 EGF82588.1 - 5.4e-12 45.6 0.0 2e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF82588.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HSDR_N PF04313.14 EGF82588.1 - 0.0004 20.4 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.22 EGF82588.1 - 0.0054 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF82588.1 - 0.0079 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF82588.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGF82588.1 - 0.015 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF82588.1 - 0.018 13.9 0.5 0.027 13.3 0.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGF82588.1 - 0.021 14.1 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 EGF82588.1 - 0.068 12.7 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF82588.1 - 0.16 11.9 0.4 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DnaJ-X PF14308.6 EGF82589.1 - 2.3e-42 144.8 0.2 3.5e-42 144.2 0.2 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGF82589.1 - 1e-23 83.2 0.9 2.2e-23 82.1 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain MetOD2 PF18548.1 EGF82590.1 - 0.031 14.4 1.1 0.089 12.9 0.5 2.0 1 1 1 2 2 2 0 Metanogen output domain 2 Erp_C PF06780.11 EGF82590.1 - 0.049 13.6 1.2 0.08 13.0 1.2 1.3 1 0 0 1 1 1 0 Erp protein C-terminus Cast PF10174.9 EGF82591.1 - 0.0025 16.2 2.7 0.0036 15.6 2.7 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.6 EGF82591.1 - 0.0044 16.8 8.9 0.0064 16.3 8.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Phage_HK97_TLTM PF06120.11 EGF82591.1 - 0.0051 16.0 1.4 0.0066 15.7 1.4 1.2 1 0 0 1 1 1 1 Tail length tape measure protein APG17 PF04108.12 EGF82591.1 - 0.0081 15.3 0.2 0.0094 15.1 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 HAP1_N PF04849.13 EGF82591.1 - 0.012 14.8 3.6 0.017 14.4 3.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FAM76 PF16046.5 EGF82591.1 - 0.016 14.6 1.6 0.019 14.3 1.6 1.2 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 EGF82591.1 - 0.029 13.3 4.7 0.039 12.8 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EGF82591.1 - 0.079 13.6 3.4 0.11 13.1 2.7 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LPP PF04728.13 EGF82591.1 - 0.13 12.7 0.7 0.41 11.1 0.4 1.9 1 1 1 2 2 2 0 Lipoprotein leucine-zipper FliD_N PF02465.18 EGF82591.1 - 0.16 12.6 10.5 0.16 12.7 1.6 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4806 PF16064.5 EGF82591.1 - 0.18 12.1 1.0 1.3 9.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4806) DivIC PF04977.15 EGF82591.1 - 0.24 11.2 0.7 0.5 10.2 0.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF16 PF01519.16 EGF82591.1 - 0.32 11.5 2.7 1.9 9.1 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4315 PF14193.6 EGF82591.1 - 0.39 10.7 3.7 0.87 9.6 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) TMPIT PF07851.13 EGF82591.1 - 0.55 9.4 2.6 0.79 8.9 2.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DHR10 PF18595.1 EGF82591.1 - 0.99 9.5 5.8 1.1 9.3 5.0 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 EGF82591.1 - 1.2 9.2 10.4 0.93 9.5 5.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.11 EGF82594.1 - 0.066 13.2 3.5 7.3 6.6 1.1 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 EGF82594.1 - 0.46 10.7 4.6 0.9 9.7 0.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ndc1_Nup PF09531.10 EGF82596.1 - 0.036 12.8 8.2 0.04 12.6 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4214 PF13946.6 EGF82596.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) WDCP PF15390.6 EGF82596.1 - 0.26 9.6 5.5 0.47 8.8 5.5 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Hid1 PF12722.7 EGF82596.1 - 5.2 5.1 7.6 6.4 4.8 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1505 PF07403.11 EGF82597.1 - 0.069 13.3 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Asp PF00026.23 EGF82598.1 - 2.1e-11 43.8 0.0 5.1e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82598.1 - 8e-05 22.5 0.0 0.00028 20.7 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DCX PF03607.17 EGF82599.1 - 0.019 15.0 0.0 0.068 13.3 0.0 2.0 1 0 0 1 1 1 0 Doublecortin RRM_Rrp7 PF17799.1 EGF82599.1 - 0.054 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DED PF01335.21 EGF82599.1 - 0.092 13.1 2.5 0.11 12.8 0.4 2.2 3 0 0 3 3 3 0 Death effector domain ABC_tran PF00005.27 EGF82600.1 - 6.2e-29 101.3 0.0 1.2e-28 100.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGF82600.1 - 6.3e-11 42.6 0.6 8.2e-07 29.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF82600.1 - 0.00021 21.8 0.0 0.0003 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGF82600.1 - 0.0011 18.8 0.1 0.0019 18.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGF82600.1 - 0.0014 18.3 0.1 0.0027 17.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGF82600.1 - 0.01 15.3 0.1 0.47 9.8 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGF82600.1 - 0.018 14.8 0.6 0.052 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 EGF82600.1 - 0.019 15.3 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 EGF82600.1 - 0.03 13.2 0.1 0.045 12.6 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) TsaE PF02367.17 EGF82600.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EGF82600.1 - 0.098 12.9 0.0 0.73 10.1 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF2620 PF10941.8 EGF82600.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Nairo_nucleo PF02477.15 EGF82601.1 - 0.0072 15.2 0.1 0.0097 14.8 0.1 1.1 1 0 0 1 1 1 1 Nucleocapsid N protein Macoilin PF09726.9 EGF82602.1 - 0.29 9.7 6.3 0.33 9.5 6.3 1.1 1 0 0 1 1 1 0 Macoilin family Asp PF00026.23 EGF82603.1 - 1.5e-14 54.1 0.1 2.4e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF82603.1 - 1.3e-06 28.3 0.4 3.1e-06 27.0 0.4 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal PheRS_DBD1 PF18552.1 EGF82604.1 - 0.059 13.1 0.1 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 PheRS DNA binding domain 1 E1-E2_ATPase PF00122.20 EGF82608.1 - 2e-26 92.6 0.6 8.3e-26 90.6 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase PQ-loop PF04193.14 EGF82608.1 - 2.2e-23 81.8 11.6 4.1e-13 48.9 1.8 4.0 3 0 0 3 3 3 2 PQ loop repeat P5-ATPase PF12409.8 EGF82608.1 - 9.2e-15 54.9 2.6 3.8e-11 43.2 4.0 3.6 2 1 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EGF82608.1 - 2.6e-14 54.0 0.0 6.4e-06 26.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF82608.1 - 0.094 12.4 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGF82608.1 - 0.17 11.6 1.7 2.6 7.7 0.1 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 EGF82609.1 - 3.4e-07 30.0 0.0 6e-05 22.8 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3153 PF11353.8 EGF82610.1 - 7.8 6.0 8.2 0.4 10.2 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3153) Coa1 PF08695.10 EGF82611.1 - 6.9e-15 54.8 0.0 8.1e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 EGF82611.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 TIM21 Voltage_CLC PF00654.20 EGF82612.1 - 1e-93 314.4 29.0 2.1e-93 313.4 29.0 1.5 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EGF82612.1 - 4e-09 36.8 0.0 4.2e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain Peptidase_M36 PF02128.15 EGF82614.1 - 1.4e-101 340.3 0.4 1.6e-101 340.2 0.4 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.15 EGF82614.1 - 0.0042 17.0 0.2 0.0059 16.5 0.2 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M50B PF13398.6 EGF82614.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like MR_MLE_N PF02746.16 EGF82614.1 - 0.2 11.9 0.5 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ank_2 PF12796.7 EGF82615.1 - 1e-25 90.1 1.5 5.9e-14 52.4 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF82615.1 - 1e-18 67.1 2.5 2.4e-10 40.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF82615.1 - 2.4e-14 52.0 0.0 1.4e-05 25.0 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGF82615.1 - 3.1e-14 53.1 0.2 1.1e-05 25.9 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGF82615.1 - 1.1e-12 47.8 1.2 0.00025 21.4 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Tfb4 PF03850.14 EGF82616.1 - 0.063 12.8 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Presenilin PF01080.17 EGF82616.1 - 1 8.0 5.8 1.3 7.7 5.8 1.1 1 0 0 1 1 1 0 Presenilin Phasin PF05597.11 EGF82616.1 - 1.2 9.1 7.4 4.3 7.4 7.5 1.8 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) LMBR1 PF04791.16 EGF82616.1 - 1.5 7.7 6.1 1.9 7.3 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Uds1 PF15456.6 EGF82616.1 - 3.4 7.9 8.5 5.2 7.3 8.5 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Tho2 PF11262.8 EGF82616.1 - 4.8 6.3 9.4 8 5.6 9.4 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spore_III_AB PF09548.10 EGF82616.1 - 6.8 6.8 7.4 18 5.4 1.0 2.7 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TMPIT PF07851.13 EGF82616.1 - 7.1 5.8 6.4 9.3 5.4 6.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mitofilin PF09731.9 EGF82617.1 - 0.01 14.7 18.4 0.013 14.3 18.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Phasin PF05597.11 EGF82617.1 - 0.12 12.4 4.3 0.26 11.3 4.3 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.13 EGF82617.1 - 0.64 10.7 2.6 2.2 8.9 2.6 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LMBR1 PF04791.16 EGF82617.1 - 3.1 6.6 5.9 3.5 6.4 5.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Enkurin PF13864.6 EGF82618.1 - 5.6e-13 49.2 0.2 8.9e-13 48.5 0.2 1.3 1 0 0 1 1 1 1 Calmodulin-binding Ysc84 PF04366.12 EGF82619.1 - 2.2e-42 143.8 0.2 3.9e-42 143.0 0.2 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGF82619.1 - 4e-13 48.7 0.1 7.2e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF82619.1 - 1.1e-09 37.8 0.1 2.4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGF82619.1 - 2.6e-09 36.8 0.0 4.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SPATA3 PF15662.5 EGF82619.1 - 0.82 10.3 9.3 1.3 9.6 9.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family UQ_con PF00179.26 EGF82620.1 - 7.4e-49 165.0 0.0 8.4e-49 164.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prenyltrans PF00432.21 EGF82621.1 - 2.9e-65 215.6 14.5 2.3e-14 52.8 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGF82621.1 - 2.7e-09 36.6 0.0 7.3e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGF82621.1 - 3.4e-08 32.9 0.0 0.0073 15.4 0.0 3.8 1 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain Telomere_Sde2_2 PF13297.6 EGF82621.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal TED_complement PF07678.14 EGF82621.1 - 0.15 11.1 0.0 12 4.8 0.0 2.7 3 0 0 3 3 3 0 A-macroglobulin TED domain DUF1748 PF08520.10 EGF82622.1 - 8.6e-12 44.8 0.0 9.1e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) BES1_N PF05687.13 EGF82622.1 - 0.23 11.8 0.0 0.28 11.5 0.0 1.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal WD40 PF00400.32 EGF82623.1 - 2.3e-16 59.8 4.2 0.00012 22.7 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82623.1 - 4.3e-12 46.2 0.0 0.059 13.7 0.0 4.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF82623.1 - 0.00036 19.6 0.0 2.6 6.9 0.0 3.3 3 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGF82623.1 - 0.029 13.1 0.1 0.92 8.2 0.0 2.7 2 1 0 3 3 3 0 Nup133 N terminal like MORN PF02493.20 EGF82624.1 - 4.4e-10 38.8 8.1 1e-05 25.1 2.8 3.7 4 0 0 4 4 4 2 MORN repeat Sen15 PF09631.10 EGF82624.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Sen15 protein TPP1 PF10341.9 EGF82625.1 - 0.0011 19.0 0.9 0.0029 17.5 0.1 2.3 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD eIF_4G1 PF12152.8 EGF82625.1 - 0.069 13.3 0.1 0.98 9.6 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 PGAP1 PF07819.13 EGF82626.1 - 1.6e-59 201.4 0.0 3e-59 200.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGF82626.1 - 0.00018 22.2 0.1 0.00033 21.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGF82626.1 - 0.0009 18.9 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF82626.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EGF82626.1 - 0.057 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 EGF82626.1 - 0.12 11.9 1.0 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Adaptin_N PF01602.20 EGF82627.1 - 9.4e-111 370.9 5.4 7.3e-109 364.7 5.4 2.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGF82627.1 - 8.3e-20 71.5 0.8 8.3e-20 71.5 0.8 3.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGF82627.1 - 1.2e-09 38.4 1.1 0.00079 19.8 0.0 4.8 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EGF82627.1 - 5.8e-08 32.3 0.4 2.2 8.7 0.1 5.6 5 0 0 5 5 5 3 HEAT repeat CDC45 PF02724.14 EGF82627.1 - 0.044 12.1 1.7 0.066 11.5 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HEAT_EZ PF13513.6 EGF82627.1 - 0.083 13.4 0.0 1.4 9.5 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat DUF4611 PF15387.6 EGF82627.1 - 0.46 10.7 8.9 20 5.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Rep_fac_C PF08542.11 EGF82628.1 - 7.3e-23 80.8 0.0 1.5e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGF82628.1 - 1.3e-11 44.6 0.2 4.6e-09 36.3 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EGF82628.1 - 1.5e-11 44.8 0.0 2.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGF82628.1 - 3.8e-06 27.0 0.0 6.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF82628.1 - 4e-05 24.1 0.0 0.0021 18.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGF82628.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGF82628.1 - 0.00018 21.8 0.1 0.21 11.9 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 EGF82628.1 - 0.00026 20.8 0.0 0.0006 19.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGF82628.1 - 0.00044 19.7 0.1 0.0042 16.5 0.1 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF5119 PF17145.4 EGF82628.1 - 0.0007 19.6 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5119) RuvB_N PF05496.12 EGF82628.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGF82628.1 - 0.0036 17.7 0.1 0.014 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EGF82628.1 - 0.0046 16.0 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 EGF82628.1 - 0.0048 16.3 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 EGF82628.1 - 0.012 16.1 0.0 0.026 15.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 EGF82628.1 - 0.014 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGF82628.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DEAD PF00270.29 EGF82628.1 - 0.028 14.2 0.1 1.2 8.9 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 EGF82628.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EGF82628.1 - 0.051 13.1 0.1 0.15 11.6 0.1 1.7 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGF82628.1 - 0.063 13.2 0.1 0.19 11.6 0.1 1.8 1 1 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 EGF82628.1 - 0.064 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain MCM PF00493.23 EGF82628.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_11 PF13086.6 EGF82628.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 EGF82628.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ RNA_helicase PF00910.22 EGF82628.1 - 0.16 12.4 0.1 0.75 10.2 0.1 2.1 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.23 EGF82628.1 - 0.21 10.2 0.1 13 4.4 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain Rad51 PF08423.11 EGF82629.1 - 1.2e-20 73.9 0.6 2e-20 73.2 0.6 1.3 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.6 EGF82629.1 - 0.00017 22.1 1.0 0.00033 21.2 1.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain PfkB PF00294.24 EGF82629.1 - 0.00039 19.8 0.0 0.015 14.6 0.1 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase RecA PF00154.21 EGF82629.1 - 0.0089 15.5 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein RNA_pol_A_CTD PF03118.15 EGF82629.1 - 0.21 11.4 0.3 0.46 10.3 0.3 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PB1 PF00564.24 EGF82631.1 - 0.00016 21.5 0.1 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 PB1 domain CTK3 PF12243.8 EGF82631.1 - 0.15 12.1 0.8 0.71 9.9 0.1 2.5 2 1 1 3 3 3 0 CTD kinase subunit gamma CTK3 G-alpha PF00503.20 EGF82632.1 - 5.5e-82 275.7 0.0 1.1e-81 274.7 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF82632.1 - 2.3e-12 46.7 0.6 2.3e-08 33.7 0.0 2.8 3 1 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 EGF82632.1 - 0.0029 17.8 0.1 3.1 8.0 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGF82632.1 - 0.012 14.9 0.3 0.17 11.2 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGF82632.1 - 0.19 11.2 0.0 0.76 9.2 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_transf_90 PF05686.12 EGF82634.1 - 7e-30 104.2 2.6 2.2e-28 99.3 0.6 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EGF82634.1 - 1.4e-05 25.4 0.0 0.00013 22.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.12 EGF82635.1 - 2.5e-31 109.0 4.5 1.7e-30 106.3 1.3 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EGF82635.1 - 0.00024 21.4 0.0 0.00049 20.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.12 EGF82636.1 - 7.8e-31 107.4 1.1 3.3e-30 105.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EGF82636.1 - 0.00024 21.4 0.0 0.0005 20.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 IDO PF01231.18 EGF82637.1 - 8.2e-120 400.5 0.0 1.8e-119 399.4 0.0 1.5 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1616 PF07760.11 EGF82638.1 - 0.34 10.2 0.0 0.34 10.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1616) TTL PF03133.15 EGF82640.1 - 7e-43 146.8 0.0 1.3e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family RdRP_3 PF00998.23 EGF82640.1 - 0.14 10.8 0.0 7.4 5.1 0.0 2.1 2 0 0 2 2 2 0 Viral RNA dependent RNA polymerase cNMP_binding PF00027.29 EGF82642.1 - 6.5e-35 119.1 0.4 2.9e-15 56.1 0.0 5.0 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EGF82642.1 - 8.9e-17 61.9 3.8 2.7e-15 57.1 3.8 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase CBS PF00571.28 EGF82643.1 - 2e-22 79.4 6.4 9.4e-07 29.2 0.1 5.4 4 2 1 5 5 5 4 CBS domain Arf PF00025.21 EGF82644.1 - 3.3e-50 170.0 0.1 4.1e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGF82644.1 - 1.1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF82644.1 - 4.1e-14 52.8 0.0 7.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGF82644.1 - 2.8e-11 43.2 0.2 1.5e-07 30.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGF82644.1 - 2e-10 40.4 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGF82644.1 - 3.2e-10 40.1 0.0 4.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGF82644.1 - 3.4e-10 39.6 0.0 4.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGF82644.1 - 3.1e-09 36.7 0.6 2.6e-07 30.4 0.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGF82644.1 - 0.0033 17.0 1.1 0.01 15.4 1.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF82644.1 - 0.0064 16.4 0.4 0.25 11.3 0.2 2.3 1 1 2 3 3 3 1 RsgA GTPase KAP_NTPase PF07693.14 EGF82644.1 - 0.011 15.0 0.1 0.087 12.0 0.3 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 EGF82644.1 - 0.013 15.7 0.0 0.4 10.9 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGF82644.1 - 0.02 15.4 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGF82644.1 - 0.068 13.7 0.1 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EGF82644.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 EGF82645.1 - 4.1e-18 65.6 0.3 4.4e-17 62.3 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain ABC2_membrane_3 PF12698.7 EGF82647.1 - 2.5e-26 92.6 28.3 3.7e-26 92.1 28.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGF82647.1 - 1.9e-24 86.7 0.0 3.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF82647.1 - 2e-11 44.3 0.4 2.5e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 EGF82647.1 - 3.6e-08 33.1 24.4 8.4e-08 31.9 24.4 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EGF82647.1 - 0.0094 15.3 11.6 0.017 14.4 11.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2705 PF10920.8 EGF82647.1 - 0.0099 15.2 11.8 0.019 14.3 11.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2705) RsgA_GTPase PF03193.16 EGF82647.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EGF82647.1 - 0.075 12.7 0.0 2.7 7.6 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGF82647.1 - 0.098 12.4 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EGF82647.1 - 0.11 11.9 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGF82647.1 - 0.14 12.6 0.2 0.24 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain MRP_L53 PF10780.9 EGF82650.1 - 6.3e-06 26.3 0.5 1.1e-05 25.5 0.5 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 zf-RING_2 PF13639.6 EGF82651.1 - 5e-11 42.8 10.2 5e-11 42.8 10.2 2.3 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 EGF82651.1 - 1.5e-08 34.7 2.8 1.5e-08 34.7 2.8 2.3 3 0 0 3 3 2 1 zinc-ribbon zf-rbx1 PF12678.7 EGF82651.1 - 2.8e-08 33.9 7.6 2.8e-08 33.9 7.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF82651.1 - 2.5e-06 27.2 10.4 2.5e-06 27.2 10.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF82651.1 - 0.00028 20.6 9.5 0.00028 20.6 9.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGF82651.1 - 0.00032 20.5 10.5 0.00032 20.5 10.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF82651.1 - 0.00042 20.1 6.1 0.00042 20.1 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF82651.1 - 0.0026 17.8 5.0 0.007 16.4 5.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGF82651.1 - 0.0058 16.6 7.6 0.008 16.2 6.0 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGF82651.1 - 0.011 15.7 8.4 0.011 15.7 8.4 2.7 2 1 1 3 3 3 0 zinc-RING finger domain Pox_A3L PF05288.11 EGF82651.1 - 0.2 11.7 1.2 0.33 11.0 0.3 1.7 1 1 1 2 2 2 0 Poxvirus A3L Protein Zn_ribbon_17 PF17120.5 EGF82651.1 - 1.4 8.6 13.3 0.033 13.8 6.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 EGF82651.1 - 2.4 8.3 11.3 6.9 6.9 5.3 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn-ribbon_8 PF09723.10 EGF82651.1 - 8.2 6.6 10.7 2.7 8.2 0.6 3.0 3 0 0 3 3 2 0 Zinc ribbon domain DUF2418 PF10332.9 EGF82652.1 - 2.9e-18 66.2 0.5 2.9e-18 66.2 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) Polysacc_deac_1 PF01522.21 EGF82653.1 - 1.6e-32 112.0 0.0 2.4e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGF82653.1 - 1.5e-25 89.4 76.7 1.3e-08 35.2 18.6 3.4 3 0 0 3 3 3 3 Chitin recognition protein Glyco_hydro_57 PF03065.15 EGF82653.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Pkinase PF00069.25 EGF82654.1 - 2e-67 227.3 0.0 2.9e-62 210.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82654.1 - 4.1e-32 111.5 0.0 2.2e-29 102.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase KA1 PF02149.19 EGF82654.1 - 8.8e-19 67.0 0.2 1.6e-18 66.2 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EGF82654.1 - 1.5e-07 31.0 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF82654.1 - 1.6e-05 24.4 0.1 3.8e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF82654.1 - 2.7e-05 23.3 0.1 5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF82654.1 - 5.1e-05 23.3 0.1 0.0014 18.6 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGF82654.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EGF82654.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EGF82654.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EGF82654.1 - 0.081 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EGF82654.1 - 0.096 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 EGF82655.1 - 1.4e-211 704.0 0.1 2.3e-210 699.9 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGF82655.1 - 1.8e-37 128.6 0.1 3.6e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGF82655.1 - 5.6e-16 58.3 0.7 1.9e-08 33.5 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGF82655.1 - 5.9e-08 32.4 6.2 2.7e-06 27.0 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGF82655.1 - 0.02 14.2 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF5089 PF17002.5 EGF82656.1 - 0.00016 21.6 16.8 0.0053 16.7 16.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 EGF82656.1 - 1.3 9.3 7.5 0.19 12.0 0.6 2.5 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.12 EGF82656.1 - 2.4 8.2 7.0 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 EGF82656.1 - 2.8 7.9 12.7 8.4 6.3 0.7 3.1 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Arm PF00514.23 EGF82657.1 - 4.3e-14 52.0 4.8 2.7e-05 24.1 0.0 6.9 7 1 1 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGF82657.1 - 1.9e-05 24.5 0.7 0.14 12.5 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGF82657.1 - 4.8e-05 23.7 0.1 5 7.6 0.1 4.1 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGF82657.1 - 0.00046 20.6 0.7 0.19 12.3 0.0 4.8 4 1 2 6 6 6 1 HEAT-like repeat DNA_pol_phi PF04931.13 EGF82657.1 - 1.6 6.7 3.9 2.4 6.2 2.4 1.8 2 0 0 2 2 2 0 DNA polymerase phi RNase_P_pop3 PF08228.11 EGF82658.1 - 5.2e-06 26.6 0.2 0.00048 20.2 0.1 3.1 1 1 0 2 2 2 1 RNase P subunit Pop3 Duffy_binding PF05424.11 EGF82658.1 - 0.011 15.8 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Duffy binding domain TPR_2 PF07719.17 EGF82660.1 - 1.1e-20 72.0 17.3 0.0019 18.2 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82660.1 - 9.1e-20 69.6 19.8 0.00062 19.5 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82660.1 - 1.4e-17 62.3 10.2 6.3e-05 22.7 0.0 7.7 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82660.1 - 2.5e-17 61.5 15.7 2.3e-05 24.2 0.1 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82660.1 - 1.7e-14 53.8 12.9 8.6e-07 29.2 0.1 6.2 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82660.1 - 1.8e-11 44.5 7.1 0.00087 19.9 0.7 5.2 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82660.1 - 1.6e-08 34.1 7.5 0.0045 16.6 0.0 5.7 6 0 0 6 6 6 3 TPR repeat TPR_14 PF13428.6 EGF82660.1 - 1.1e-07 32.1 6.4 0.72 10.8 0.1 6.7 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82660.1 - 7.5e-07 29.1 0.7 14 6.3 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF82660.1 - 3.2e-06 27.6 9.5 0.022 15.2 0.4 4.9 3 2 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF82660.1 - 1.6e-05 25.0 8.2 0.023 14.9 1.2 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGF82660.1 - 0.00028 21.3 10.4 33 5.4 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGF82660.1 - 0.00049 19.9 6.2 0.028 14.1 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 EGF82660.1 - 0.0013 18.8 3.2 1.6 8.9 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGF82660.1 - 0.0038 16.5 0.9 1.4 8.1 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EGF82660.1 - 0.0039 16.9 1.5 15 5.3 0.0 4.2 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 EGF82660.1 - 0.027 14.4 6.7 2.1 8.3 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat MSA-2c PF12238.8 EGF82660.1 - 0.075 13.0 4.5 0.26 11.3 3.9 2.2 2 1 0 2 2 2 0 Merozoite surface antigen 2c SNAP PF14938.6 EGF82660.1 - 0.1 12.0 2.8 2.6 7.4 0.1 2.9 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP PPR PF01535.20 EGF82660.1 - 0.12 12.6 4.8 2.8 8.4 0.1 4.5 5 0 0 5 5 4 0 PPR repeat DUF4810 PF16068.5 EGF82660.1 - 0.15 12.6 0.3 1.4 9.5 0.0 2.8 3 0 0 3 3 1 0 Domain of unknown function (DUF4810) DIM1 PF02966.16 EGF82661.1 - 2.9e-68 227.7 0.1 3.3e-68 227.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGF82661.1 - 3.1e-06 27.1 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGF82661.1 - 0.023 15.0 0.2 0.033 14.5 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF1365 PF07103.11 EGF82662.1 - 2.7e-64 217.1 2.2 4.5e-64 216.4 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.20 EGF82663.1 - 6.2e-39 133.9 1.7 8.3e-39 133.5 1.7 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EGF82663.1 - 1.8e-13 50.5 0.0 2.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF82663.1 - 2e-13 50.8 0.0 4.4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF82663.1 - 1.7e-12 47.8 0.0 2.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF82663.1 - 9.9e-11 42.3 0.0 1.6e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF82663.1 - 2.3e-10 40.6 0.0 3.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF82663.1 - 1.5e-07 31.1 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGF82663.1 - 1.7e-07 30.9 0.0 2.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 EGF82663.1 - 5.7e-07 29.3 0.0 4.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) TehB PF03848.14 EGF82663.1 - 1.9e-05 24.2 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 EGF82663.1 - 0.00035 20.3 0.0 0.005 16.5 0.0 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EGF82663.1 - 0.00086 19.1 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGF82663.1 - 0.0024 17.5 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 EGF82663.1 - 0.036 14.2 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGF82663.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GidB PF02527.15 EGF82663.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF1295 PF06966.12 EGF82664.1 - 3.2e-48 164.3 6.4 4.1e-48 164.0 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGF82664.1 - 0.0029 17.6 7.2 0.0056 16.7 6.1 2.2 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Tmemb_185A PF10269.9 EGF82664.1 - 0.092 12.4 12.8 0.023 14.4 9.1 1.7 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein STAG PF08514.11 EGF82665.1 - 7.7e-24 83.8 0.4 7.7e-24 83.8 0.4 2.7 3 0 0 3 3 3 1 STAG domain DUF5461 PF17545.2 EGF82666.1 - 0.017 15.4 0.4 0.14 12.4 0.2 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5461) Doppel PF11466.8 EGF82666.1 - 3.8 7.2 5.5 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 Prion-like protein Doppel SRP54 PF00448.22 EGF82667.1 - 1.6e-77 259.6 0.3 2.7e-77 258.9 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGF82667.1 - 1.5e-29 102.5 0.4 1.5e-29 102.5 0.4 4.8 3 1 2 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.19 EGF82667.1 - 5.1e-21 74.7 3.8 1.1e-20 73.6 3.8 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGF82667.1 - 9.3e-06 25.3 0.5 5.3e-05 22.9 0.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGF82667.1 - 1.7e-05 25.0 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF82667.1 - 7.1e-05 23.3 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EGF82667.1 - 8.3e-05 22.6 0.0 0.00032 20.8 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EGF82667.1 - 0.00027 20.0 0.2 0.0026 16.8 0.2 2.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EGF82667.1 - 0.00069 20.0 0.2 0.0031 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGF82667.1 - 0.0011 18.4 2.7 0.27 10.6 0.0 3.0 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 EGF82667.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ResIII PF04851.15 EGF82667.1 - 0.0019 18.2 0.2 0.012 15.7 0.2 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit APS_kinase PF01583.20 EGF82667.1 - 0.0046 16.9 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 EGF82667.1 - 0.0057 16.9 0.1 0.02 15.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF82667.1 - 0.013 15.3 0.1 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGF82667.1 - 0.015 15.3 0.0 0.073 13.2 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 EGF82667.1 - 0.018 15.0 0.1 0.069 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EGF82667.1 - 0.031 14.2 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 EGF82667.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.17 EGF82667.1 - 0.053 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Thymidylate kinase AAA_19 PF13245.6 EGF82667.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EGF82667.1 - 0.068 12.3 3.5 0.051 12.7 0.5 2.6 2 1 0 2 2 2 0 Anion-transporting ATPase ATP_bind_1 PF03029.17 EGF82667.1 - 0.068 12.9 0.1 0.068 12.9 0.1 2.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EGF82667.1 - 0.1 12.4 0.2 16 5.2 0.1 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 EGF82667.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2209 PF09974.9 EGF82667.1 - 0.12 12.7 0.2 0.39 11.1 0.2 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) NTPase_1 PF03266.15 EGF82667.1 - 0.16 11.9 1.5 1.5 8.7 1.5 2.3 1 1 0 1 1 1 0 NTPase AAA_28 PF13521.6 EGF82667.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NMT PF01233.19 EGF82668.1 - 0.18 11.6 0.0 0.43 10.4 0.0 1.6 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain CH PF00307.31 EGF82669.1 - 1.1e-18 67.4 0.0 2e-18 66.5 0.0 1.4 2 0 0 2 2 2 1 Calponin homology (CH) domain RPN6_C_helix PF18503.1 EGF82669.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain PH PF00169.29 EGF82670.1 - 0.0018 18.7 2.1 0.03 14.8 0.6 3.6 2 1 0 2 2 2 1 PH domain Peptidase_C12 PF01088.21 EGF82671.1 - 0.099 12.4 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 B9-C2 PF07162.11 EGF82672.1 - 2.5e-34 118.9 0.0 6.5e-24 85.0 0.0 2.0 1 1 1 2 2 2 2 Ciliary basal body-associated, B9 protein Tetraspanin PF00335.20 EGF82673.1 - 3.1e-12 46.7 2.7 8.9e-12 45.2 2.7 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF3040 PF11239.8 EGF82673.1 - 0.98 9.7 5.9 0.67 10.3 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) SR-25 PF10500.9 EGF82674.1 - 4.5e-22 78.8 0.2 4.5e-22 78.8 0.2 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Latrophilin PF02354.16 EGF82674.1 - 0.064 12.3 6.8 0.056 12.5 5.7 1.3 1 1 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Apt1 PF10351.9 EGF82674.1 - 1.4 7.7 10.6 1.8 7.4 10.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWIRM PF04433.17 EGF82675.1 - 0.00024 21.4 0.0 0.0005 20.3 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Nt_Gln_amidase PF09764.9 EGF82676.1 - 1.8e-50 171.1 0.1 2.2e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase GST_N PF02798.20 EGF82676.1 - 0.011 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HSP70 PF00012.20 EGF82677.1 - 9.9e-144 479.8 2.4 4.9e-142 474.2 2.4 2.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF82677.1 - 1.1e-09 37.6 0.0 2.4e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein Membr_traf_MHD PF10540.9 EGF82681.1 - 6.9e-07 29.5 0.0 0.00075 19.7 0.0 2.2 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain TPR_11 PF13414.6 EGF82682.1 - 0.028 14.1 0.1 0.17 11.6 0.1 2.4 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 EGF82682.1 - 0.076 13.9 5.0 0.77 10.7 0.4 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Lectin_N PF03954.14 EGF82682.1 - 0.1 12.3 2.6 0.14 11.9 0.1 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain TPR_19 PF14559.6 EGF82682.1 - 0.11 13.1 3.7 2.4 8.7 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82682.1 - 1.5 9.0 7.3 53 4.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_S26 PF10502.9 EGF82683.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 Pkinase PF00069.25 EGF82684.1 - 3.4e-59 200.4 0.0 3.9e-58 196.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82684.1 - 3.2e-42 144.6 0.0 1.4e-34 119.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF82684.1 - 0.0003 19.7 0.1 0.0006 18.7 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF82684.1 - 0.043 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGF82684.1 - 0.044 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD1 PF04904.13 EGF82684.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) DNA_ligase_A_M PF01068.21 EGF82685.1 - 2.1e-61 207.1 0.2 3.5e-61 206.4 0.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGF82685.1 - 5e-43 147.4 0.1 9.3e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGF82685.1 - 1.7e-25 89.5 0.0 3.2e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGF82685.1 - 0.00013 22.3 0.3 0.00027 21.3 0.3 1.6 1 0 0 1 1 1 1 RNA ligase Polysacc_deac_1 PF01522.21 EGF82686.1 - 2.6e-29 101.6 0.0 4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase TPPK_C PF12555.8 EGF82686.1 - 0.66 10.1 3.8 0.82 9.8 0.0 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal SAP130_C PF16014.5 EGF82686.1 - 5.3 6.0 12.6 8 5.4 12.6 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Polysacc_deac_1 PF01522.21 EGF82687.1 - 9.6e-31 106.3 0.0 1.6e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase MGC-24 PF05283.11 EGF82687.1 - 2.5 8.5 8.8 3.9 7.9 8.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SAP130_C PF16014.5 EGF82687.1 - 9.1 5.2 12.2 11 5.0 12.2 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus TFIIA_gamma_N PF02268.16 EGF82690.1 - 5.3e-24 84.0 0.2 8.1e-24 83.4 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EGF82690.1 - 1.2e-20 73.4 0.6 1.7e-20 72.8 0.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Glyco_trans_2_3 PF13632.6 EGF82691.1 - 1.5e-06 28.3 3.0 1.5e-06 28.3 3.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.15 EGF82691.1 - 0.00028 19.7 7.4 0.00028 19.7 7.4 3.3 2 2 1 3 3 3 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EGF82691.1 - 1.2 9.0 3.2 22 4.8 3.2 2.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 MFS_1 PF07690.16 EGF82692.1 - 1.4e-14 53.8 39.2 6.3e-13 48.4 8.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EGF82692.1 - 9.9e-14 51.4 6.7 9.9e-14 51.4 6.7 2.2 3 0 0 3 3 3 1 Nodulin-like Acatn PF13000.7 EGF82692.1 - 0.0092 14.5 0.2 0.024 13.2 0.0 1.6 2 0 0 2 2 2 1 Acetyl-coenzyme A transporter 1 DUF3611 PF12263.8 EGF82692.1 - 2.8 7.8 9.5 0.21 11.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) B12D PF06522.11 EGF82693.1 - 0.075 12.8 0.1 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit E1-E2_ATPase PF00122.20 EGF82694.1 - 1.3e-31 109.5 0.0 2.9e-30 105.1 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 EGF82694.1 - 3.8e-16 59.3 0.2 3.8e-16 59.3 0.2 2.4 3 0 0 3 3 3 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EGF82694.1 - 2.8e-12 47.4 0.0 0.00036 20.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGF82694.1 - 0.0002 21.1 10.6 0.0006 19.6 10.6 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGF82694.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Glyco_hydro_16 PF00722.21 EGF82696.1 - 1.3e-29 102.9 0.0 1.9e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Hamartin PF04388.12 EGF82698.1 - 2.5e-08 33.1 5.3 4.6e-05 22.3 1.0 3.1 3 0 0 3 3 3 2 Hamartin protein Spc7 PF08317.11 EGF82698.1 - 6 5.6 28.5 0.21 10.5 14.3 2.8 2 1 0 3 3 3 0 Spc7 kinetochore protein PspB PF06667.12 EGF82698.1 - 6.3 6.9 10.4 2.7 8.1 0.6 3.2 2 1 1 3 3 3 0 Phage shock protein B OCRE PF17780.1 EGF82699.1 - 0.062 13.3 11.4 0.2 11.7 11.4 1.9 1 0 0 1 1 1 0 OCRE domain CD34_antigen PF06365.12 EGF82699.1 - 0.065 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Pox_A14 PF05767.12 EGF82699.1 - 0.11 12.7 0.4 0.22 11.7 0.4 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 RIFIN PF02009.16 EGF82699.1 - 0.41 10.5 3.6 0.61 9.9 3.6 1.2 1 0 0 1 1 1 0 Rifin Dicty_REP PF05086.12 EGF82699.1 - 2.3 6.1 3.9 3.1 5.7 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BPD_transp_1 PF00528.22 EGF82699.1 - 9.2 6.0 11.2 0.73 9.5 5.9 1.8 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Methyltransf_33 PF10017.9 EGF82700.1 - 3e-86 289.4 0.1 4.3e-86 288.9 0.1 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EGF82700.1 - 5.6e-19 68.7 3.2 6.3e-17 62.0 3.2 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF1566 PF07603.11 EGF82700.1 - 0.043 14.2 0.4 0.11 12.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) Methyltransf_12 PF08242.12 EGF82700.1 - 0.11 13.2 0.0 0.36 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PikAIV_N PF18605.1 EGF82701.1 - 0.14 11.7 0.9 3.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Med9 PF07544.13 EGF82702.1 - 0.037 14.1 0.1 0.065 13.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cyclin_C_2 PF16899.5 EGF82703.1 - 1.8e-18 66.8 0.3 1.6e-16 60.6 0.1 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EGF82703.1 - 1.9e-06 27.6 1.0 3.3e-06 26.8 0.1 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain COG5 PF10392.9 EGF82704.1 - 1.9e-17 63.7 6.8 2e-17 63.6 2.0 2.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.11 EGF82704.1 - 0.001 19.2 2.7 0.018 15.1 1.8 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.9 EGF82704.1 - 0.006 16.4 0.5 0.54 10.0 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 EGF82704.1 - 0.0068 16.3 2.6 0.0068 16.3 2.6 2.5 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain Spc7 PF08317.11 EGF82704.1 - 0.016 14.1 4.0 0.032 13.1 0.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 EGF82704.1 - 0.03 13.3 2.5 0.064 12.2 2.5 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Vps51 PF08700.11 EGF82704.1 - 0.038 14.1 2.7 0.072 13.2 1.2 2.4 2 0 0 2 2 2 0 Vps51/Vps67 MscS_porin PF12795.7 EGF82704.1 - 0.2 11.2 1.4 0.47 10.0 1.4 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain 7TMR-HDED PF07697.11 EGF82704.1 - 0.23 11.5 4.5 1.9 8.5 4.4 2.5 1 1 1 2 2 2 0 7TM-HD extracellular Vps54_N PF10475.9 EGF82704.1 - 0.24 10.7 9.0 0.53 9.5 9.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Sec34 PF04136.15 EGF82704.1 - 0.74 9.7 7.4 0.52 10.2 3.5 2.8 2 0 0 2 2 2 0 Sec34-like family H-kinase_dim PF02895.14 EGF82704.1 - 1.5 9.3 3.8 0.87 10.0 0.5 2.5 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SesA PF17107.5 EGF82704.1 - 1.5 9.0 4.7 1.3 9.2 0.3 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DASH_Dad3 PF08656.10 EGF82704.1 - 5 7.3 6.0 14 5.8 2.2 3.2 2 1 0 2 2 2 0 DASH complex subunit Dad3 DSPn PF14671.6 EGF82705.1 - 3.1e-52 176.8 0.7 3.1e-52 176.8 0.7 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGF82705.1 - 9.6e-15 54.6 0.1 1.7e-13 50.5 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF82705.1 - 7e-07 29.0 0.0 2.5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGF82705.1 - 0.00018 21.7 0.0 0.0012 19.0 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EGF82705.1 - 0.0081 15.8 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGF82705.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family HA2 PF04408.23 EGF82706.1 - 9.5e-20 70.9 0.3 1.9e-18 66.7 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGF82706.1 - 6.1e-15 55.5 0.0 1.6e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGF82706.1 - 4.7e-08 33.0 0.0 1.6e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGF82706.1 - 0.00024 21.4 0.0 0.00075 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EGF82706.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 EGF82706.1 - 0.022 14.4 0.0 0.082 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGF82706.1 - 0.055 14.0 0.1 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGF82706.1 - 0.06 13.4 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EGF82706.1 - 0.14 11.6 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Vps4_C PF09336.10 EGF82707.1 - 0.027 14.4 0.4 0.07 13.1 0.4 1.7 1 1 0 1 1 1 0 Vps4 C terminal oligomerisation domain MRP-S24 PF14955.6 EGF82707.1 - 0.089 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Pkinase PF00069.25 EGF82708.1 - 3.2e-59 200.4 0.0 3.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82708.1 - 3e-36 125.0 0.0 4.1e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82708.1 - 2.6e-08 33.5 0.0 8.1e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF82708.1 - 9.7e-08 31.2 0.0 1.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGF82708.1 - 2.2e-06 26.9 0.4 2.8e-06 26.5 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF82708.1 - 0.00091 19.2 0.0 1.5 8.6 0.1 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EGF82708.1 - 0.0037 16.9 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGF82708.1 - 0.033 13.5 0.2 0.045 13.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGF82709.1 - 6.1e-48 163.5 0.0 1.6e-47 162.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82709.1 - 1e-25 90.5 0.0 3.4e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82709.1 - 4.7e-07 29.4 0.0 6.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF82709.1 - 6.9e-05 21.8 0.0 9.9e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF82709.1 - 0.00011 22.2 0.5 0.0098 15.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EGF82709.1 - 0.0025 17.4 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGF82709.1 - 0.1 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tyrosinase PF00264.20 EGF82710.1 - 4.1e-37 128.6 2.1 4.1e-37 128.6 2.1 2.4 2 2 0 2 2 2 1 Common central domain of tyrosinase Sec63 PF02889.16 EGF82711.1 - 5.9e-168 556.5 0.2 2.5e-87 292.3 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGF82711.1 - 1.2e-44 152.2 0.0 2.1e-26 92.7 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGF82711.1 - 1.2e-37 128.4 2.6 1.2e-37 128.4 2.6 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 EGF82711.1 - 2.1e-24 86.4 0.0 7.7e-16 58.6 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF82711.1 - 1.2e-12 48.1 0.0 2.4e-08 34.3 0.0 3.8 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGF82711.1 - 1.2e-07 32.1 0.0 0.0072 16.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EGF82711.1 - 0.005 16.3 0.0 0.083 12.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EGF82711.1 - 0.061 12.4 0.0 8 5.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein GEN1_C PF18380.1 EGF82711.1 - 0.41 11.6 2.9 0.55 11.1 0.2 2.6 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain TPR_1 PF00515.28 EGF82712.1 - 1.2e-10 40.7 2.4 5.1e-05 22.9 0.0 3.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82712.1 - 6.1e-10 38.4 0.7 0.00018 21.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82712.1 - 4.9e-09 35.6 0.4 0.001 19.0 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82712.1 - 5.3e-09 35.6 4.7 9.7e-05 22.3 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82712.1 - 2.9e-07 30.7 1.5 0.00034 20.8 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82712.1 - 3.3e-05 23.6 0.5 0.22 11.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82712.1 - 0.00033 21.2 3.8 16 6.6 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82712.1 - 0.00095 19.4 0.1 1.3 9.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGF82712.1 - 0.0027 17.5 1.3 0.0085 15.8 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EGF82712.1 - 0.019 14.3 3.7 0.058 12.8 1.4 2.3 1 1 0 2 2 2 0 MalT-like TPR region NIT PF08376.10 EGF82712.1 - 0.038 14.5 0.3 0.1 13.0 0.1 1.8 2 0 0 2 2 2 0 Nitrate and nitrite sensing TPR_5 PF12688.7 EGF82712.1 - 0.081 13.2 0.3 3.2 8.0 0.0 3.2 3 2 1 4 4 4 0 Tetratrico peptide repeat TPR_6 PF13174.6 EGF82712.1 - 2.4 9.0 0.0 2.4 9.0 0.0 3.5 5 0 0 5 5 3 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 EGF82713.1 - 3.9e-24 82.4 10.6 1.2e-05 24.5 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGF82713.1 - 1.4e-22 79.9 8.8 2.2e-11 44.0 2.3 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGF82713.1 - 1.5e-19 68.5 9.5 0.00016 21.0 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGF82713.1 - 4.9e-17 60.3 7.1 0.0006 19.5 0.3 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGF82713.1 - 6e-10 38.8 15.4 0.0043 16.9 1.0 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGF82713.1 - 4.6e-07 30.1 0.1 0.0071 16.7 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGF82713.1 - 0.0003 20.7 7.2 0.024 14.6 0.6 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGF82713.1 - 0.0028 18.0 0.1 2.7 8.4 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 EGF82713.1 - 0.013 15.7 2.5 1.5 9.1 1.9 3.2 2 1 1 3 3 3 0 Dockerin type I domain Fungal_trans PF04082.18 EGF82714.1 - 8.5e-16 57.8 2.1 2.4e-15 56.3 2.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF82714.1 - 3.2e-09 36.7 12.4 7.4e-09 35.6 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3653 PF12375.8 EGF82714.1 - 0.096 12.8 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Phage protein MFS_1 PF07690.16 EGF82715.1 - 5.5e-26 91.3 20.5 7.1e-24 84.4 16.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF82715.1 - 0.00013 20.9 13.9 0.0054 15.6 3.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter Nuc_H_symport PF03825.16 EGF82715.1 - 0.0043 16.1 0.8 0.0043 16.1 0.8 2.4 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_2 PF13347.6 EGF82715.1 - 0.0049 15.5 7.3 0.021 13.4 7.4 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 EGF82715.1 - 0.0095 14.8 1.4 0.4 9.5 0.6 2.5 2 1 0 2 2 2 2 MFS_1 like family EF-hand_6 PF13405.6 EGF82716.1 - 5.2e-17 60.3 9.3 0.029 14.3 0.0 7.8 8 0 0 8 8 8 6 EF-hand domain EF-hand_8 PF13833.6 EGF82716.1 - 1.3e-14 53.8 3.4 9e-05 22.2 0.1 7.1 7 0 0 7 7 7 3 EF-hand domain pair EF-hand_7 PF13499.6 EGF82716.1 - 3.1e-11 43.6 19.2 0.039 14.4 0.0 8.2 8 1 1 9 9 9 3 EF-hand domain pair EF-hand_1 PF00036.32 EGF82716.1 - 1.2e-08 33.9 8.0 0.084 12.5 0.0 7.5 8 0 0 8 8 8 3 EF hand RST PF12174.8 EGF82716.1 - 3.9e-08 33.1 13.5 0.33 10.9 0.2 6.9 5 1 1 6 6 6 3 RCD1-SRO-TAF4 (RST) plant domain EF-hand_11 PF08976.11 EGF82716.1 - 5e-08 33.7 8.5 0.23 12.3 0.2 6.6 7 0 0 7 7 7 2 EF-hand domain FGAR-AT_linker PF18072.1 EGF82716.1 - 0.0018 18.8 2.2 15 6.2 0.0 6.2 7 0 0 7 7 7 1 Formylglycinamide ribonucleotide amidotransferase linker domain Vps4_C PF09336.10 EGF82716.1 - 0.012 15.6 0.1 28 4.8 0.0 4.1 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain p25-alpha PF05517.12 EGF82716.1 - 0.92 9.7 4.0 13 5.9 0.0 4.0 3 1 1 4 4 4 0 p25-alpha DnaJ PF00226.31 EGF82717.1 - 3.3e-16 59.2 0.0 4.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 EGF82717.1 - 2.4e-06 27.2 0.4 4e-06 26.4 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger ORC3_N PF07034.11 EGF82718.1 - 1.8e-55 188.3 0.2 2.8e-55 187.7 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EGF82718.1 - 4.5e-30 104.5 0.1 8e-27 94.0 0.1 2.4 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal HEAT_2 PF13646.6 EGF82719.1 - 8.6e-24 83.8 0.9 1.1e-10 41.8 0.1 4.6 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 EGF82719.1 - 3.5e-09 36.1 1.1 0.02 15.1 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EGF82719.1 - 3.7e-05 24.1 1.8 2.5 8.7 0.0 5.0 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EGF82719.1 - 0.003 17.6 1.6 2 8.4 0.1 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EGF82719.1 - 0.053 14.2 0.1 13 6.8 0.0 3.1 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGF82719.1 - 0.077 13.6 0.4 1.8 9.2 0.1 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Bmt2 PF11968.8 EGF82720.1 - 4.7e-63 213.0 0.0 8.6e-63 212.1 0.0 1.4 2 0 0 2 2 2 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_8 PF05148.15 EGF82720.1 - 4.7e-05 23.3 0.0 9.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF4476 PF14771.6 EGF82720.1 - 0.1 12.9 0.3 24 5.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) DUF3748 PF12566.8 EGF82720.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Dynein_attach_N PF15867.5 EGF82721.1 - 0.03 14.3 0.1 0.076 13.0 0.1 1.7 1 0 0 1 1 1 0 Dynein attachment factor N-terminus RasGEF PF00617.19 EGF82722.1 - 9.2e-43 146.5 0.6 2.2e-42 145.3 0.5 1.7 1 1 0 1 1 1 1 RasGEF domain PH_9 PF15410.6 EGF82722.1 - 6.4e-10 39.4 0.1 3.4e-06 27.4 0.1 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 EGF82722.1 - 8.7e-10 39.1 0.4 6.7e-06 26.6 0.1 3.1 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 EGF82722.1 - 9.7e-05 22.7 0.9 0.035 14.5 0.4 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain His_Me_b4a2 PF18275.1 EGF82724.1 - 0.00096 19.2 0.1 0.0024 17.9 0.1 1.6 1 0 0 1 1 1 1 His-Me finger endonuclease beta4-alpha2 domain UDPGP PF01704.18 EGF82725.1 - 2.2e-59 201.1 0.0 2.8e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGF82725.1 - 0.026 14.9 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain cobW PF02492.19 EGF82726.1 - 2.3e-44 151.1 0.6 2.9e-44 150.8 0.6 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGF82726.1 - 0.0042 17.0 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EGF82726.1 - 0.01 15.7 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EGF82726.1 - 0.015 15.2 0.2 5.2 6.9 0.1 2.5 2 1 0 2 2 2 0 RsgA GTPase MukB PF04310.12 EGF82726.1 - 0.037 13.8 0.1 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 EGF82726.1 - 0.041 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EGF82726.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EGF82726.1 - 0.17 11.6 0.4 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Exo_endo_phos PF03372.23 EGF82728.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C3HC4_3 PF13920.6 EGF82729.1 - 0.0012 18.7 9.8 0.0022 17.8 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF82729.1 - 0.0049 17.2 12.2 0.0082 16.5 12.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGF82729.1 - 0.33 10.9 12.3 0.58 10.2 12.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGF82729.1 - 0.38 10.6 12.1 0.84 9.5 12.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF82729.1 - 0.44 10.5 13.4 0.76 9.7 13.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF82729.1 - 6.3 6.9 10.7 14 5.8 10.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EGF82729.1 - 7.1 6.5 12.4 14 5.6 12.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SSB PF00436.25 EGF82730.1 - 9.8e-13 48.0 1.5 1e-09 38.3 1.5 2.3 1 1 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 EGF82730.1 - 0.049 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain WD40 PF00400.32 EGF82731.1 - 7.8e-43 143.6 23.8 2.9e-08 34.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82731.1 - 1.8e-22 79.4 5.9 4e-05 23.8 0.1 6.2 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF82731.1 - 2.4e-09 37.4 3.0 0.0036 17.2 0.2 2.9 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 EGF82731.1 - 0.0086 15.2 0.0 0.57 9.2 0.0 2.2 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EGF82731.1 - 0.0099 14.7 0.5 0.56 8.9 0.1 2.2 2 0 0 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 EGF82731.1 - 0.028 13.8 0.0 13 5.0 0.0 3.3 2 1 0 3 3 3 0 WD40-like domain DUF234 PF03008.14 EGF82732.1 - 0.089 13.3 0.7 5.8 7.4 0.2 2.6 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function DCX PF03607.17 EGF82733.1 - 1.6e-33 114.6 0.1 5.4e-16 58.4 0.1 2.2 2 0 0 2 2 2 2 Doublecortin Tim17 PF02466.19 EGF82734.1 - 0.016 15.6 12.9 0.18 12.2 13.0 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family LRR_4 PF12799.7 EGF82735.1 - 2.2e-07 31.1 1.0 1.8 9.1 0.0 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGF82735.1 - 6.1e-05 22.8 2.0 6 7.2 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.7 EGF82735.1 - 0.00025 20.9 0.0 0.00074 19.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EGF82735.1 - 0.086 12.6 0.5 2.2 8.1 0.0 3.2 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EGF82735.1 - 0.58 10.9 7.4 1.6e+02 3.5 0.0 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat Peptidase_S10 PF00450.22 EGF82737.1 - 5.1e-122 408.3 1.7 6.6e-122 407.9 1.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase SNF5 PF04855.12 EGF82738.1 - 2.9e-55 187.6 0.4 4.4e-55 187.1 0.0 1.4 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 DEAD PF00270.29 EGF82739.1 - 6.4e-43 146.6 0.0 1.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF82739.1 - 1.2e-24 86.7 0.0 4e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGF82739.1 - 9.5e-21 73.8 0.0 2.5e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGF82739.1 - 1.7e-06 28.1 0.0 3.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGF82739.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGF82739.1 - 0.011 15.0 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Nup96 PF12110.8 EGF82740.1 - 3.9e-57 193.6 0.0 7.8e-57 192.6 0.0 1.5 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGF82740.1 - 1.2e-43 148.8 0.0 2.3e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EGF82740.1 - 7e-08 33.2 217.6 0.00058 20.7 17.6 9.5 3 2 5 8 8 8 4 Nucleoporin FG repeat region tRNA_int_endo PF01974.17 EGF82741.1 - 8.7e-18 64.2 0.0 1.5e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Melibiase_2 PF16499.5 EGF82743.1 - 0.064 12.4 0.2 0.084 12.0 0.2 1.1 1 0 0 1 1 1 0 Alpha galactosidase A SYF2 PF08231.12 EGF82746.1 - 1.8e-51 174.7 13.7 1.8e-51 174.7 13.7 1.9 1 1 1 2 2 2 1 SYF2 splicing factor Prominin PF05478.11 EGF82746.1 - 1.4 6.8 4.1 0.39 8.6 1.5 1.4 2 0 0 2 2 2 0 Prominin Anillin_N PF16018.5 EGF82746.1 - 1.6 9.4 7.4 1.3 9.7 2.4 2.3 2 0 0 2 2 2 0 Anillin N-terminus zf-HC5HC2H_2 PF13832.6 EGF82747.1 - 2.3e-13 50.3 10.9 2.3e-13 50.3 10.9 4.8 6 0 0 6 6 6 1 PHD-zinc-finger like domain BAH PF01426.18 EGF82747.1 - 1.4e-10 41.1 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 EGF82747.1 - 8.9e-10 38.7 6.5 8.9e-10 38.7 6.5 5.3 4 2 2 6 6 6 3 PHD-like zinc-binding domain PHD_2 PF13831.6 EGF82747.1 - 4.5e-09 35.7 10.3 4.9e-07 29.2 2.4 5.6 8 0 0 8 8 8 2 PHD-finger PHD PF00628.29 EGF82747.1 - 1.7e-08 34.2 21.6 1e-06 28.5 4.4 5.7 7 0 0 7 7 7 3 PHD-finger C1_1 PF00130.22 EGF82747.1 - 0.016 15.0 1.1 0.016 15.0 1.1 7.6 6 3 2 8 8 8 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1033 PF06279.11 EGF82747.1 - 0.036 14.3 0.4 0.11 12.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-binding PF00249.31 EGF82747.1 - 0.15 12.3 0.1 0.54 10.5 0.1 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain AT_hook PF02178.19 EGF82747.1 - 3.5 7.8 11.4 14 6.0 2.8 3.2 2 0 0 2 2 2 0 AT hook motif UQ_con PF00179.26 EGF82748.1 - 3.7e-47 159.5 0.0 4.3e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGF82748.1 - 0.00095 18.9 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGF82748.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EGF82748.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF3844 PF12955.7 EGF82749.1 - 7.5e-25 87.1 2.7 1.5e-24 86.2 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) MerT PF02411.15 EGF82749.1 - 0.69 10.0 5.4 0.96 9.5 0.3 2.3 2 0 0 2 2 2 0 MerT mercuric transport protein UQ_con PF00179.26 EGF82750.1 - 1.5e-31 109.0 0.0 1.6e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VirE PF05272.11 EGF82751.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E PspB PF06667.12 EGF82751.1 - 0.73 9.9 4.6 16 5.6 0.1 3.6 4 0 0 4 4 4 0 Phage shock protein B AAA_6 PF12774.7 EGF82752.1 - 6.7e-155 515.0 4.0 3.9e-154 512.5 0.0 4.0 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGF82752.1 - 2.8e-135 451.5 6.8 2.8e-135 451.5 6.8 4.3 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGF82752.1 - 2.5e-111 371.8 1.4 9.1e-108 360.1 0.0 3.7 3 0 0 3 3 3 2 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGF82752.1 - 1.5e-109 365.3 0.3 1.7e-108 361.9 0.1 3.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGF82752.1 - 2.6e-92 307.9 1.6 2.6e-92 307.9 1.6 3.3 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGF82752.1 - 1.2e-81 272.6 0.0 9e-80 266.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGF82752.1 - 5.3e-58 195.5 0.3 7e-57 191.8 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGF82752.1 - 6.8e-53 179.9 11.6 6.8e-53 179.9 11.6 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGF82752.1 - 2.6e-49 166.3 0.0 2.5e-46 156.6 0.0 3.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGF82752.1 - 1.2e-31 109.4 0.0 6.4e-31 107.1 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGF82752.1 - 1e-18 67.6 0.2 3.1e-05 24.0 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGF82752.1 - 3.1e-18 65.8 0.1 2.4e-17 62.9 0.0 2.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 EGF82752.1 - 1.2e-06 28.8 0.0 0.37 11.1 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 EGF82752.1 - 7.9e-06 26.3 0.7 1.7 9.1 0.0 5.3 5 1 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF82752.1 - 0.001 19.5 0.0 1.9 8.9 0.0 4.1 4 0 0 4 4 3 1 AAA ATPase domain EF-hand_1 PF00036.32 EGF82752.1 - 0.0011 18.3 0.2 0.0049 16.3 0.2 2.2 1 0 0 1 1 1 1 EF hand Mg_chelatase PF01078.21 EGF82752.1 - 0.0017 17.7 0.3 0.53 9.6 0.0 3.1 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGF82752.1 - 0.0041 17.7 0.2 0.38 11.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EGF82752.1 - 0.0067 15.5 0.0 2.2 7.2 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EGF82752.1 - 0.024 15.0 0.5 34 4.9 0.0 4.4 5 0 0 5 5 3 0 RNA helicase AAA_30 PF13604.6 EGF82752.1 - 0.03 14.0 0.1 5.8 6.6 0.2 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGF82752.1 - 0.045 13.9 0.1 24 5.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain ATG16 PF08614.11 EGF82752.1 - 0.048 13.9 15.0 0.0083 16.4 1.4 3.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) EF-hand_6 PF13405.6 EGF82752.1 - 0.056 13.4 0.1 0.23 11.5 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EGF82752.1 - 0.058 13.9 1.8 0.29 11.6 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 EGF82752.1 - 0.083 12.4 0.1 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 EF hand Sigma54_activat PF00158.26 EGF82752.1 - 0.12 12.1 0.0 0.52 10.0 0.0 2.1 2 0 0 2 2 1 0 Sigma-54 interaction domain Laminin_II PF06009.12 EGF82752.1 - 0.79 9.7 22.7 0.0063 16.5 1.6 4.5 4 0 0 4 4 4 0 Laminin Domain II DASH_Dam1 PF08653.10 EGF82752.1 - 2.8 7.8 6.9 15 5.4 0.5 4.7 4 0 0 4 4 4 0 DASH complex subunit Dam1 PWWP PF00855.17 EGF82753.1 - 1.6e-18 66.9 1.7 4.5e-18 65.4 0.7 2.3 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 EGF82753.1 - 0.01 15.8 0.2 0.05 13.6 0.2 2.3 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Ribosomal_L7Ae PF01248.26 EGF82754.1 - 3e-23 81.4 0.0 3.4e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CAP_GLY PF01302.25 EGF82755.1 - 6.8e-15 54.8 0.1 1.1e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Nanovirus_C8 PF05629.11 EGF82757.1 - 0.039 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein PCI PF01399.27 EGF82758.1 - 3.4e-06 27.5 0.0 3.4e-06 27.5 0.0 4.1 3 1 0 3 3 3 1 PCI domain YbaJ PF10757.9 EGF82758.1 - 0.29 11.7 2.8 5 7.7 0.1 2.9 3 0 0 3 3 3 0 Biofilm formation regulator YbaJ Phtf-FEM1B_bdg PF12129.8 EGF82759.1 - 6.1 6.7 8.2 0.24 11.2 1.7 2.0 1 1 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor ATP-synt_F6 PF05511.11 EGF82760.1 - 0.063 13.7 0.0 0.27 11.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 SH3_2 PF07653.17 EGF82761.1 - 0.0006 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PX PF00787.24 EGF82761.1 - 0.021 14.8 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 PX domain DUF2071 PF09844.9 EGF82761.1 - 0.2 11.2 3.7 0.28 10.8 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (COG2071) Ysc84 PF04366.12 EGF82762.1 - 3.8e-42 143.1 0.5 5.9e-42 142.5 0.5 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGF82762.1 - 3e-14 52.4 0.4 6.8e-14 51.2 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGF82762.1 - 3.9e-13 48.9 0.0 9.5e-13 47.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGF82762.1 - 2.2e-12 46.6 0.1 4.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.7 EGF82763.1 - 5e-11 42.7 1.1 2.6e-06 27.7 0.2 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF82763.1 - 2.3e-07 30.5 2.6 0.00048 19.8 0.8 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 EGF82763.1 - 0.0086 16.5 3.3 6.1 7.8 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_9 PF14580.6 EGF82763.1 - 0.089 12.3 1.0 0.31 10.5 0.9 1.7 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EGF82763.1 - 0.22 11.7 3.4 8.3 6.8 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat FlaC_arch PF05377.11 EGF82765.1 - 0.21 12.0 7.9 1.3 9.5 0.2 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) FapA PF03961.13 EGF82765.1 - 4.1 5.9 11.7 7.3 5.1 5.3 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-C2H2_8 PF15909.5 EGF82766.1 - 0.00013 22.2 1.2 0.00031 21.0 1.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EGF82766.1 - 0.12 12.8 0.6 0.32 11.5 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.26 EGF82766.1 - 0.91 10.1 14.8 1.5 9.5 0.2 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EGF82766.1 - 2.1 9.0 11.1 46 4.8 0.2 4.2 3 1 0 3 3 3 0 FOXP coiled-coil domain BORCS6 PF10157.9 EGF82767.1 - 5e-10 39.8 0.1 6.3e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Mg_trans_NIPA PF05653.14 EGF82768.1 - 2e-28 99.4 23.1 6.2e-17 61.6 6.6 2.6 3 0 0 3 3 3 2 Magnesium transporter NIPA EamA PF00892.20 EGF82768.1 - 1.6e-05 25.1 4.4 1.6e-05 25.1 4.4 4.4 4 1 0 4 4 4 1 EamA-like transporter family TMEM234 PF10639.9 EGF82768.1 - 0.00015 21.8 0.1 0.00044 20.3 0.1 1.8 1 0 0 1 1 1 1 Putative transmembrane family 234 Tetraspanin PF00335.20 EGF82768.1 - 9.9 5.8 15.7 0.042 13.5 3.3 3.0 3 1 1 4 4 4 0 Tetraspanin family Homoserine_dh PF00742.19 EGF82769.1 - 6.5e-52 175.9 0.0 1.3e-51 174.9 0.0 1.5 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGF82769.1 - 2e-17 63.9 0.0 3.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Translat_reg PF01818.17 EGF82769.1 - 0.05 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator Pribosyltran_N PF13793.6 EGF82770.1 - 7.1e-48 161.4 0.7 9.9e-47 157.7 0.2 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGF82770.1 - 2.1e-41 142.0 2.1 2.1e-35 122.5 0.4 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGF82770.1 - 2.3e-17 63.0 3.3 3.2e-15 56.0 0.6 2.6 3 0 0 3 3 3 2 Phosphoribosyl transferase domain SecE PF00584.20 EGF82771.1 - 1.1e-17 63.7 0.6 1.2e-17 63.5 0.6 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NUC153 PF08159.12 EGF82772.1 - 1.6e-10 40.6 1.2 3.5e-10 39.5 1.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EGF82772.1 - 0.054 14.4 0.2 85 4.3 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat SHNi-TPR PF10516.9 EGF82773.1 - 1.8e-12 46.5 0.2 6.9e-12 44.6 0.0 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EGF82773.1 - 1.1e-07 32.0 0.3 1.1e-07 32.0 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82773.1 - 8.5e-07 28.6 4.8 0.001 19.0 0.0 3.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82773.1 - 6.8e-06 25.7 0.1 0.028 14.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82773.1 - 1.3e-05 24.7 0.1 0.0015 18.2 0.0 3.4 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 EGF82773.1 - 1.7e-05 24.7 0.1 0.0024 18.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82773.1 - 0.00055 19.8 1.4 0.69 10.1 1.4 3.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82773.1 - 0.0042 17.7 6.0 0.0098 16.5 0.2 3.3 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82773.1 - 0.12 12.3 0.1 0.6 10.1 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82773.1 - 0.13 12.7 0.1 63 4.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82773.1 - 0.32 11.9 4.9 7.6 7.6 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF572 PF04502.13 EGF82773.1 - 2.8 7.5 8.7 4.3 6.9 8.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RRM_1 PF00076.22 EGF82774.1 - 2e-43 146.0 1.0 1.5e-20 72.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF82774.1 - 3.4e-09 36.4 0.2 0.021 14.7 0.0 3.9 4 0 0 4 4 4 3 Occluded RNA-recognition motif RL PF17797.1 EGF82774.1 - 7.8e-06 25.8 1.6 0.035 14.0 0.0 3.5 3 0 0 3 3 3 2 RL domain Nup35_RRM PF05172.13 EGF82774.1 - 6.6e-05 22.8 0.9 0.03 14.3 0.0 3.3 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGF82774.1 - 0.00019 21.4 0.4 1.8 8.7 0.0 3.5 3 0 0 3 3 3 2 RNA binding motif NRDE-2 PF08424.10 EGF82774.1 - 0.00031 20.0 7.4 0.16 11.1 0.1 4.2 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference STOP PF05217.12 EGF82776.1 - 1.2 9.6 5.5 18 5.7 0.1 3.6 3 0 0 3 3 3 0 STOP protein Histidinol_dh PF00815.20 EGF82777.1 - 1.5e-161 538.0 1.4 1.9e-161 537.6 1.4 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EGF82777.1 - 5.2e-23 80.7 0.2 9.9e-23 79.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EGF82777.1 - 1.9e-12 47.4 0.1 6.3e-12 45.8 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EGF82777.1 - 0.033 14.4 0.0 0.094 12.9 0.0 1.8 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Cas_Csx9 PF09658.10 EGF82777.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) Oxidored_FMN PF00724.20 EGF82777.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family PAP_central PF04928.17 EGF82778.1 - 9.2e-110 365.5 0.0 1.3e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGF82778.1 - 2.4e-46 157.5 0.3 7e-46 156.0 0.3 1.8 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGF82778.1 - 8.2e-14 51.7 0.1 2.1e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGF82778.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NIF PF03031.18 EGF82779.1 - 1.1e-23 83.7 0.0 2.2e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3335 PF11814.8 EGF82779.1 - 5.6e-05 22.7 0.1 0.00012 21.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase_C39 like family PTCB-BRCT PF12738.7 EGF82779.1 - 0.00074 19.4 0.4 0.0021 18.0 0.4 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EGF82779.1 - 0.001 19.4 0.0 0.0031 17.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RraA-like PF03737.15 EGF82780.1 - 2.1e-25 89.7 0.1 2.8e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA SARAF PF06682.12 EGF82781.1 - 1.1e-90 304.6 8.1 1.4e-90 304.3 8.1 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis AMP-binding PF00501.28 EGF82782.1 - 5.1e-79 265.8 0.0 3.9e-75 253.0 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGF82782.1 - 4.6e-50 170.6 2.2 7.2e-50 170.0 2.2 1.2 1 0 0 1 1 1 1 Condensation domain FSH1 PF03959.13 EGF82782.1 - 3.1e-23 82.6 0.0 5.8e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PP-binding PF00550.25 EGF82782.1 - 2.1e-20 72.8 0.4 5.8e-09 36.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGF82782.1 - 0.00012 23.0 0.0 0.00038 21.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PBSX_XtrA PF17356.2 EGF82782.1 - 0.086 12.7 0.2 0.26 11.2 0.2 1.8 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Picorna_P3A PF06363.11 EGF82782.1 - 0.37 10.7 1.6 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Picornaviridae P3A protein Ribosomal_L10 PF00466.20 EGF82783.1 - 3.5e-23 81.6 0.8 5e-23 81.1 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGF82783.1 - 1.6e-20 72.8 0.2 2.9e-20 72.0 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGF82783.1 - 5.8e-17 62.1 4.2 5.8e-17 62.1 4.2 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein RabGAP-TBC PF00566.18 EGF82784.1 - 3.6e-14 53.0 3.1 2.8e-13 50.0 0.5 2.9 3 1 0 3 3 3 1 Rab-GTPase-TBC domain TLD PF07534.16 EGF82784.1 - 1.1e-13 51.6 0.0 2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 TLD TM1506 PF08973.10 EGF82784.1 - 0.086 12.5 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) BING4CT PF08149.11 EGF82785.1 - 1.1e-41 140.6 0.0 3.4e-39 132.5 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 EGF82785.1 - 2.8e-06 26.6 0.0 5.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EGF82785.1 - 2e-05 25.3 0.3 0.004 18.0 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82785.1 - 2.7e-05 24.4 0.0 0.4 11.0 0.0 4.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGF82785.1 - 0.0054 16.3 0.0 0.04 13.5 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain zf-C2H2 PF00096.26 EGF82786.1 - 1.3e-10 41.1 22.3 5.8e-06 26.5 0.3 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF82786.1 - 5e-08 33.0 11.5 0.0019 18.5 0.5 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF82786.1 - 0.00013 22.5 18.7 0.0018 18.9 0.1 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGF82786.1 - 0.0026 17.7 2.5 0.0031 17.5 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf_CopZ PF18423.1 EGF82786.1 - 0.0076 16.2 0.6 3.6 7.6 0.0 3.0 3 0 0 3 3 3 2 Zinc binding domain zf-C2H2_8 PF15909.5 EGF82786.1 - 0.68 10.3 7.3 0.45 10.8 2.8 3.0 2 2 1 3 3 3 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 EGF82786.1 - 6.4 7.0 9.0 9.6 6.4 0.1 3.8 3 1 0 3 3 3 0 Zic proteins zinc finger domain OTU PF02338.19 EGF82787.1 - 1.6e-28 99.7 0.1 2.4e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGF82787.1 - 2.2e-07 30.6 0.0 7.8e-05 22.2 0.0 2.0 1 1 1 2 2 2 2 Peptidase C65 Otubain Microtub_bind PF13931.6 EGF82788.1 - 0.00036 20.9 2.7 0.00045 20.6 2.7 1.1 1 0 0 1 1 1 1 Kinesin-associated microtubule-binding DUF4482 PF14818.6 EGF82788.1 - 0.26 12.2 4.9 0.15 12.9 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) Band_3_cyto PF07565.13 EGF82788.1 - 0.37 10.5 3.7 0.38 10.5 3.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mannosyl_trans2 PF04188.13 EGF82789.1 - 3.5e-84 283.7 33.0 4e-84 283.5 33.0 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) MIIP PF15734.5 EGF82791.1 - 7.9e-08 32.2 8.6 2.5e-07 30.5 8.6 1.8 1 1 0 1 1 1 1 Migration and invasion-inhibitory Joubert PF15392.6 EGF82791.1 - 0.018 14.8 4.1 0.029 14.1 4.1 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated DUF4490 PF14892.6 EGF82792.1 - 1.3e-23 83.0 1.9 1.6e-23 82.7 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Glyco_H_20C_C PF18088.1 EGF82793.1 - 4.5e-34 118.0 0.0 7.4e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 EGF82793.1 - 5.5e-07 29.3 0.0 1.1e-05 25.0 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Sec23_trunk PF04811.15 EGF82794.1 - 3.3e-69 233.1 0.1 5.2e-69 232.5 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGF82794.1 - 2.3e-25 88.4 0.7 6.7e-25 86.9 0.7 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGF82794.1 - 2.1e-20 73.2 0.0 4.1e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGF82794.1 - 6.8e-15 54.8 5.6 1.3e-14 53.9 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGF82794.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGF82794.1 - 0.028 13.8 0.2 0.058 12.8 0.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain bVLRF1 PF18826.1 EGF82795.1 - 1.3e-55 187.3 0.1 2.9e-55 186.2 0.1 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 EGF82795.1 - 3e-12 46.2 1.0 6.1e-12 45.2 1.0 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_5 PF13857.6 EGF82795.1 - 2.7e-07 30.7 0.1 7.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGF82795.1 - 4.1e-06 27.0 0.1 1.6e-05 25.2 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGF82795.1 - 0.00012 22.6 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGF82795.1 - 0.00096 19.4 0.0 0.0032 17.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EGF82795.1 - 0.0046 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PLATZ PF04640.14 EGF82795.1 - 0.056 14.1 0.9 0.056 14.1 0.9 2.8 3 0 0 3 3 3 0 PLATZ transcription factor Opiods_neuropep PF01160.18 EGF82795.1 - 0.1 12.7 0.5 0.24 11.5 0.5 1.6 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide zf-MYND PF01753.18 EGF82795.1 - 2.9 8.1 6.7 0.19 11.8 0.6 2.0 2 0 0 2 2 2 0 MYND finger WD40 PF00400.32 EGF82796.1 - 5.4e-07 30.2 10.9 0.14 13.1 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 EGF82796.1 - 0.0002 20.8 0.0 0.0047 16.3 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 EGF82796.1 - 0.017 13.8 0.0 0.04 12.6 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SNF2_N PF00176.23 EGF82797.1 - 3.8e-67 226.5 0.0 6.8e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF82797.1 - 8.7e-22 77.6 0.0 3.4e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF82797.1 - 0.00018 21.6 0.0 0.0012 18.8 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGF82797.1 - 0.00057 19.1 1.4 0.0052 16.0 0.0 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 GWT1 PF06423.12 EGF82798.1 - 1.6e-29 103.0 4.1 1.6e-29 103.0 4.1 2.8 2 1 0 2 2 2 1 GWT1 Lebercilin PF15619.6 EGF82799.1 - 4.9e-35 120.9 29.3 1.2e-34 119.7 29.3 1.6 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease LZ_Tnp_IS66 PF13007.7 EGF82799.1 - 1.2 9.9 4.6 0.44 11.4 0.5 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain TMF_TATA_bd PF12325.8 EGF82799.1 - 1.7 8.9 21.0 4.1 7.7 3.2 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 EGF82799.1 - 3.8 7.6 25.2 11 6.2 3.5 4.0 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EGF82799.1 - 8.6 6.9 20.0 2.8 8.5 4.4 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region Cpn60_TCP1 PF00118.24 EGF82800.1 - 4.5e-117 391.7 8.1 9e-103 344.5 5.1 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EGF82800.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat MCD PF05292.11 EGF82801.1 - 1.4e-67 228.0 0.0 2.7e-40 138.6 0.0 2.1 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain SNF2_N PF00176.23 EGF82802.1 - 8.4e-65 218.8 0.2 1.5e-64 217.9 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EGF82802.1 - 1.4e-22 79.3 0.1 5.2e-14 51.9 0.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EGF82802.1 - 8.5e-22 77.4 2.5 1.5e-21 76.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EGF82802.1 - 1.9e-20 73.3 0.0 1.8e-19 70.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF82802.1 - 4.1e-11 43.2 0.0 1.7e-10 41.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGF82802.1 - 2.9e-07 30.0 0.3 2.9e-07 30.0 0.3 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EGF82802.1 - 1e-05 25.8 1.6 2.4e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Chromodomain helicase DNA-binding domain 1 ERCC3_RAD25_C PF16203.5 EGF82802.1 - 0.001 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CHDCT2 PF08074.11 EGF82802.1 - 0.002 18.4 2.0 0.0046 17.2 0.0 2.5 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain CDH1_2_SANT_HL1 PF18375.1 EGF82802.1 - 0.0064 17.1 0.7 0.023 15.4 0.0 2.3 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SH3BGR PF04908.15 EGF82802.1 - 0.066 13.4 0.3 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein SurA_N_2 PF13623.6 EGF82802.1 - 0.55 10.1 4.5 1 9.2 0.7 2.6 2 0 0 2 2 2 0 SurA N-terminal domain tRNA_bind PF01588.20 EGF82803.1 - 2.9e-30 104.2 0.3 5e-30 103.5 0.3 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Viral_protease PF08715.10 EGF82803.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease Pre-PUA PF17832.1 EGF82804.1 - 0.001 19.7 0.2 0.017 15.8 0.0 3.0 3 0 0 3 3 3 1 Pre-PUA-like domain DUF1409 PF07197.12 EGF82804.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) U3_assoc_6 PF08640.11 EGF82804.1 - 0.18 11.9 5.3 0.35 10.9 2.8 2.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DUF5117 PF17148.4 EGF82804.1 - 0.36 10.6 5.0 0.076 12.9 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5117) DUF4407 PF14362.6 EGF82804.1 - 0.46 9.8 23.4 0.68 9.2 18.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cytochrom_C_2 PF01322.20 EGF82804.1 - 1.4 9.8 6.5 2.9 8.8 3.0 2.8 2 0 0 2 2 2 0 Cytochrome C' Pkinase PF00069.25 EGF82805.1 - 3.1e-44 151.3 0.1 2.6e-22 79.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82805.1 - 1.6e-20 73.5 0.0 1.7e-12 47.2 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 EGF82805.1 - 1.1e-18 66.7 0.1 2.9e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EGF82805.1 - 0.028 13.7 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EGF82806.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain PhyH PF05721.13 EGF82807.1 - 4.2e-07 30.4 0.0 2.1e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) STI1 PF17830.1 EGF82809.1 - 4e-16 58.7 2.1 8.2e-16 57.7 1.6 1.8 2 0 0 2 2 2 1 STI1 domain TPR_17 PF13431.6 EGF82809.1 - 0.00052 20.2 0.4 0.0038 17.5 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82809.1 - 0.011 15.5 3.5 0.61 10.0 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 EGF82810.1 - 3.8e-46 156.4 1.7 3.8e-46 156.4 1.7 1.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGF82810.1 - 3.3e-13 49.4 0.0 8.6e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain cNMP_binding PF00027.29 EGF82811.1 - 6.8e-19 67.7 0.1 3.2e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EGF82811.1 - 4e-06 26.4 16.0 1.5 9.1 0.0 9.0 10 0 0 10 10 10 2 Leucine Rich repeat F-box PF00646.33 EGF82811.1 - 0.0045 16.8 0.0 0.035 14.0 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EGF82811.1 - 0.0062 16.9 10.7 2.6 8.6 0.2 5.3 3 2 2 6 6 6 2 Leucine Rich repeats (2 copies) Glyco_hydro_59 PF02057.15 EGF82811.1 - 0.041 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 LRR_1 PF00560.33 EGF82811.1 - 4.7 8.1 13.3 21 6.2 1.7 6.3 5 2 0 5 5 5 0 Leucine Rich Repeat UPF0160 PF03690.13 EGF82812.1 - 9.8e-125 416.4 0.0 1.2e-124 416.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SRPRB PF09439.10 EGF82813.1 - 2.7e-40 137.8 0.0 3.6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGF82813.1 - 4.2e-14 52.4 0.0 5.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF82813.1 - 1.5e-06 28.2 0.0 3.8e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF82813.1 - 1.7e-05 24.3 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGF82813.1 - 0.00015 21.3 0.0 0.001 18.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGF82813.1 - 0.0043 16.6 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EGF82813.1 - 0.0045 16.8 0.8 0.61 9.8 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Roc PF08477.13 EGF82813.1 - 0.0071 16.6 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGF82813.1 - 0.008 16.1 0.5 0.032 14.1 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGF82813.1 - 0.017 15.5 0.8 0.037 14.4 0.7 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGF82813.1 - 0.021 14.8 0.3 0.12 12.2 0.3 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGF82813.1 - 0.022 15.2 0.4 0.042 14.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter T2SSE PF00437.20 EGF82813.1 - 0.05 12.6 0.1 0.1 11.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGF82813.1 - 0.057 13.2 0.4 0.15 11.9 0.2 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGF82813.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ras PF00071.22 EGF82813.1 - 0.077 12.6 0.0 0.097 12.3 0.0 1.4 1 1 0 1 1 1 0 Ras family AAA PF00004.29 EGF82813.1 - 0.091 13.2 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGF82813.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region His_binding PF02098.16 EGF82814.1 - 0.039 14.0 0.6 0.061 13.4 0.6 1.2 1 0 0 1 1 1 0 Tick histamine binding protein Pkinase PF00069.25 EGF82815.1 - 3.6e-43 147.8 0.0 3.5e-31 108.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82815.1 - 5.6e-33 114.3 0.0 1.3e-32 113.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF82815.1 - 7.3e-08 31.6 0.0 1.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF82815.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF82815.1 - 0.0067 15.8 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF82815.1 - 0.06 13.3 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_5 PF07994.12 EGF82816.1 - 7.2e-150 498.8 0.1 8.5e-150 498.6 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGF82816.1 - 5.3e-46 155.4 0.2 9.5e-46 154.5 0.2 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase SIS PF01380.22 EGF82816.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 SIS domain Carb_anhydrase PF00194.21 EGF82817.1 - 4.8e-35 121.3 0.3 1.1e-34 120.1 0.3 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase HNH_2 PF13391.6 EGF82820.1 - 0.00061 19.9 0.3 0.00061 19.9 0.3 1.9 3 0 0 3 3 3 1 HNH endonuclease Retrotran_gag_2 PF14223.6 EGF82821.1 - 0.092 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Nmad5 PF18757.1 EGF82822.1 - 0.038 14.2 1.6 0.16 12.2 0.2 2.4 2 1 1 3 3 3 0 Nucleotide modification associated domain 5 PAS_11 PF14598.6 EGF82822.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.8 3 0 0 3 3 3 0 PAS domain Phasin PF05597.11 EGF82822.1 - 1.7 8.6 8.3 0.79 9.7 0.6 2.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Actin PF00022.19 EGF82823.1 - 7.1e-52 176.4 0.0 2.9e-32 111.8 0.1 3.3 1 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EGF82823.1 - 7.3e-13 48.0 0.0 1.8e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EGF82823.1 - 0.028 14.8 0.0 0.096 13.1 0.0 2.0 1 1 0 1 1 1 0 Cell division protein FtsA Pkinase PF00069.25 EGF82824.1 - 4.9e-43 147.4 0.0 4.8e-31 108.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82824.1 - 6.7e-33 114.1 0.0 1.5e-32 112.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF82824.1 - 7.2e-08 31.6 0.0 1.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGF82824.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF82824.1 - 0.0066 15.8 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF82824.1 - 0.06 13.3 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_5 PF07994.12 EGF82825.1 - 8.5e-151 501.8 0.1 1e-150 501.6 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGF82825.1 - 5.4e-46 155.3 0.2 9.5e-46 154.5 0.2 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase SIS PF01380.22 EGF82825.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 SIS domain RNase_P_p30 PF01876.16 EGF82827.1 - 2.5e-52 177.5 0.6 2.9e-52 177.2 0.6 1.1 1 0 0 1 1 1 1 RNase P subunit p30 SIS PF01380.22 EGF82827.1 - 0.034 14.0 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 SIS domain Phi_1 PF04674.12 EGF82828.1 - 2.8e-37 128.5 3.7 7.1e-37 127.2 3.7 1.7 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region Mito_carr PF00153.27 EGF82829.1 - 2.6e-63 209.9 5.1 2.7e-22 78.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 EGF82830.1 - 1.7e-22 79.9 27.0 3.6e-15 55.8 5.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF82830.1 - 0.00032 19.7 1.5 0.00032 19.7 1.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Redoxin PF08534.10 EGF82831.1 - 2.4e-36 124.7 0.1 2.7e-36 124.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGF82831.1 - 4.1e-10 39.7 0.0 4.8e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L34e PF01199.18 EGF82832.1 - 2.2e-43 146.5 1.9 3.3e-43 145.9 1.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e PRKCSH PF07915.13 EGF82833.1 - 2.1e-08 35.1 0.3 6.7e-08 33.4 0.3 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGF82833.1 - 0.05 13.3 0.8 0.14 11.9 0.8 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Herpes_UL87 PF03043.14 EGF82833.1 - 0.052 12.0 0.0 0.095 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family PPR PF01535.20 EGF82834.1 - 3.6e-16 58.2 1.8 0.043 14.1 0.1 7.8 7 0 0 7 7 7 4 PPR repeat PPR_2 PF13041.6 EGF82834.1 - 4e-16 58.9 3.5 9.3e-07 28.9 0.0 5.6 4 1 2 6 6 6 3 PPR repeat family PPR_long PF17177.4 EGF82834.1 - 2.6e-11 43.3 3.0 7.3e-07 28.8 0.1 3.3 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EGF82834.1 - 1.9e-09 37.5 5.1 0.0026 17.8 0.1 4.9 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGF82834.1 - 0.00018 21.2 2.1 0.87 9.3 0.0 4.8 6 0 0 6 6 6 1 PPR repeat CstA_5TM PF13722.6 EGF82834.1 - 0.024 15.0 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA TPR_6 PF13174.6 EGF82834.1 - 0.27 12.0 2.4 4.3 8.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EGF82834.1 - 1.3 9.5 4.5 1.5 9.2 0.0 3.2 3 1 0 4 4 4 0 Bacterial transcriptional activator domain UPF0139 PF03669.13 EGF82835.1 - 2.6e-21 75.3 0.0 3e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Glyco_hydro_15 PF00723.21 EGF82837.1 - 1e-121 406.9 0.0 1.3e-121 406.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBF PF03914.17 EGF82838.1 - 4.7e-48 163.4 1.0 9.5e-48 162.4 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Aldedh PF00171.22 EGF82839.1 - 1e-122 410.0 0.0 1.3e-122 409.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nsp1_C PF05064.13 EGF82841.1 - 2.6e-32 111.0 5.2 5.7e-32 109.9 5.2 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EGF82841.1 - 0.00022 22.0 88.6 0.04 14.8 24.8 5.3 1 1 3 4 4 4 3 Nucleoporin FG repeat region MIP-T3_C PF17749.1 EGF82841.1 - 0.077 13.0 5.0 0.15 12.0 5.0 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region APG6_N PF17675.1 EGF82841.1 - 3.5 8.1 11.5 7.4 7.1 11.5 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region UCH PF00443.29 EGF82842.1 - 0.00066 19.2 0.0 0.026 14.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribonuclease_3 PF00636.26 EGF82843.1 - 3.8e-39 133.5 0.0 1.5e-19 70.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF82843.1 - 7.2e-27 94.1 0.0 5.8e-11 42.7 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EGF82843.1 - 1.2e-15 57.4 0.0 5e-15 55.4 0.0 2.2 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 EGF82843.1 - 1.5e-13 51.1 0.8 5.6e-13 49.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF82843.1 - 5.6e-13 49.0 0.0 1.7e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF82843.1 - 1.2e-09 38.5 0.1 4.3e-09 36.7 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 EGF82843.1 - 0.0025 18.5 2.2 3.4 8.5 1.2 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif SNF2_N PF00176.23 EGF82843.1 - 0.016 13.9 0.0 0.032 13.0 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain PELOTA_1 PF15608.6 EGF82844.1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain BSP_II PF05432.11 EGF82844.1 - 7.1 6.2 11.2 9.1 5.9 11.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) UPRTase PF14681.6 EGF82846.1 - 7.9e-63 211.6 0.0 8.9e-63 211.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGF82846.1 - 0.0011 18.5 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain VQ PF05678.14 EGF82846.1 - 0.064 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 VQ motif Cpn60_TCP1 PF00118.24 EGF82847.1 - 3.1e-168 560.4 2.3 3.9e-168 560.1 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP20 PF00011.21 EGF82849.1 - 2.6e-15 56.4 0.0 3.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PIH1_CS PF18201.1 EGF82849.1 - 7.6e-05 23.1 0.0 9.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EGF82849.1 - 9.8e-05 21.8 0.0 0.00021 20.8 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PNP_phzG_C PF10590.9 EGF82850.1 - 4.8e-21 74.6 2.7 1.1e-20 73.5 0.5 2.5 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EGF82850.1 - 4.3e-19 68.5 0.0 6.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EGF82850.1 - 7.8e-06 26.4 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Molybdopterin_N PF18364.1 EGF82850.1 - 0.39 10.8 2.6 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain Chitin_synth_2 PF03142.15 EGF82851.1 - 3e-215 715.8 4.4 3.6e-215 715.6 4.4 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGF82851.1 - 8.3e-15 55.2 2.5 1.6e-14 54.3 2.5 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF82851.1 - 5.6e-12 46.0 0.0 6.1e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGF82851.1 - 1.6e-05 24.5 0.0 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGF82851.1 - 1.9e-05 24.5 0.0 0.00053 19.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Myosin_head PF00063.21 EGF82852.1 - 5.5e-63 213.3 1.2 6.4e-62 209.7 1.2 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DUF3859 PF12975.7 EGF82852.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) DUF3752 PF12572.8 EGF82853.1 - 2.3e-16 60.7 18.3 2.9e-12 47.4 9.5 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3752) HNH_2 PF13391.6 EGF82855.1 - 3e-05 24.1 0.0 6.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGF82855.1 - 0.08 13.1 2.3 0.92 9.7 2.3 2.4 1 1 0 1 1 1 0 HNH endonuclease MOR2-PAG1_N PF14222.6 EGF82857.1 - 1.6e-121 407.0 0.1 3.5e-121 405.9 0.1 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EGF82857.1 - 2e-53 181.9 2.2 1.4e-51 175.9 2.2 3.1 1 1 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGF82857.1 - 6.8e-33 113.5 4.1 1.3e-22 79.5 0.0 5.0 3 1 2 5 5 5 4 Cell morphogenesis central region HLH PF00010.26 EGF82857.1 - 6.5e-17 61.2 1.7 2.1e-16 59.6 1.7 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.27 EGF82857.1 - 2.7e-07 30.4 0.0 5.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein PQQ PF01011.21 EGF82857.1 - 0.2 11.6 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat LAMTOR PF15454.6 EGF82858.1 - 1.3e-14 54.6 2.7 2.4e-14 53.7 2.7 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF4727 PF15856.5 EGF82858.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4727) ATG7_N PF16420.5 EGF82859.1 - 2.6e-97 326.1 0.0 3.4e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGF82859.1 - 2.5e-43 148.2 0.0 4e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGF82859.1 - 0.0026 17.8 0.1 0.034 14.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGF82859.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EGF82859.1 - 0.19 11.0 0.0 0.62 9.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_4 PF12799.7 EGF82860.1 - 9.7e-05 22.7 13.9 0.15 12.5 0.8 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF82860.1 - 9.8e-05 21.9 1.5 0.0082 15.7 0.2 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 EGF82860.1 - 0.00033 20.4 12.0 0.014 15.1 0.7 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EGF82860.1 - 6 7.2 15.0 26 5.2 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Brix PF04427.18 EGF82861.1 - 5.3e-25 88.7 0.2 9.4e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 Brix domain Ribosomal_L18_c PF14204.6 EGF82861.1 - 7.1 7.7 12.1 0.25 12.3 1.0 2.9 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region Pkinase PF00069.25 EGF82862.1 - 8.7e-63 212.1 0.0 1e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82862.1 - 2.9e-38 131.7 0.0 4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82862.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF82862.1 - 0.00086 19.3 0.3 0.019 14.9 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF82862.1 - 0.027 13.4 0.1 0.037 13.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGF82862.1 - 0.043 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_2 PF07719.17 EGF82863.1 - 7.1e-13 47.6 7.3 0.00044 20.2 0.1 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82863.1 - 1.3e-08 34.3 8.2 0.0065 16.2 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82863.1 - 2e-08 34.4 0.3 0.0043 17.8 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82863.1 - 1.5e-06 28.0 17.9 0.0095 16.1 0.2 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat C2-C2_1 PF11618.8 EGF82863.1 - 6.8e-06 26.2 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 First C2 domain of RPGR-interacting protein 1 TPR_19 PF14559.6 EGF82863.1 - 9.8e-06 26.0 0.6 0.12 12.9 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82863.1 - 1.1e-05 25.0 0.0 0.00011 21.8 0.0 2.8 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 EGF82863.1 - 0.00055 20.1 1.5 22 5.7 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82863.1 - 0.0028 18.3 0.0 3.4 8.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82863.1 - 0.0057 16.9 9.5 0.015 15.5 0.3 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGF82863.1 - 0.007 15.6 0.7 2.3 7.4 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82863.1 - 0.025 14.6 0.1 0.24 11.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF82863.1 - 0.04 14.1 5.0 11 6.3 0.0 4.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_lig_T4_1 PF09511.10 EGF82865.1 - 7.4e-77 258.1 0.0 1.1e-76 257.5 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EGF82865.1 - 1.1e-32 113.4 0.1 2e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EGF82865.1 - 2.5e-26 92.6 0.0 3.8e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 EGF82865.1 - 0.018 15.6 0.1 0.058 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGF82865.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGF82865.1 - 0.08 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rap_GAP PF02145.15 EGF82866.1 - 2.4e-61 206.6 0.0 3.3e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP OTU PF02338.19 EGF82867.1 - 0.12 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 OTU-like cysteine protease zf-H2C2_2 PF13465.6 EGF82868.1 - 9.1e-10 38.5 10.7 6.1e-07 29.6 1.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF82868.1 - 1.5e-09 37.9 15.0 0.0057 17.4 3.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGF82868.1 - 1.9e-09 37.5 15.6 0.0043 17.4 0.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGF82868.1 - 7.2e-06 25.9 7.1 0.51 10.4 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGF82868.1 - 3.5e-05 24.0 4.9 3.5e-05 24.0 4.9 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EGF82868.1 - 0.006 16.8 1.6 11 6.4 0.0 3.8 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 EGF82868.1 - 0.025 14.2 1.9 0.42 10.2 0.0 3.0 2 1 1 3 3 3 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 EGF82868.1 - 0.029 14.3 0.3 0.029 14.3 0.3 2.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 EGF82868.1 - 0.032 14.8 1.2 1.5 9.5 0.2 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 EGF82868.1 - 0.044 14.5 3.8 10 6.8 0.4 3.1 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Spt46 PF17734.1 EGF82868.1 - 0.097 12.5 6.0 0.18 11.6 0.2 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 zf-met PF12874.7 EGF82868.1 - 0.13 12.6 4.6 13 6.4 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ribosomal_S26e PF01283.19 EGF82868.1 - 0.28 11.6 2.2 0.29 11.6 0.1 2.1 2 1 1 3 3 3 0 Ribosomal protein S26e zf-H2C2_5 PF13909.6 EGF82868.1 - 7.3 6.4 15.4 4.2 7.2 1.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Pho88 PF10032.9 EGF82869.1 - 1.2e-58 197.4 0.3 1.4e-58 197.1 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) NDK PF00334.19 EGF82870.1 - 2.1e-51 173.5 0.0 2.4e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase peroxidase PF00141.23 EGF82871.1 - 1.2e-48 165.8 0.0 1.9e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase IN_DBD_C PF00552.21 EGF82871.1 - 0.17 11.2 0.3 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 Integrase DNA binding domain zf-RING_2 PF13639.6 EGF82873.1 - 0.24 11.8 0.5 0.55 10.6 0.5 1.6 1 0 0 1 1 1 0 Ring finger domain GPI-anchored PF10342.9 EGF82875.1 - 0.29 11.9 4.2 0.28 12.0 2.6 1.7 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UCH PF00443.29 EGF82876.1 - 1e-34 120.2 0.0 2.2e-34 119.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF82876.1 - 1.6e-06 27.9 4.7 0.00051 19.7 4.7 3.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4837 PF16125.5 EGF82876.1 - 0.18 10.8 0.2 0.45 9.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) MscS_porin PF12795.7 EGF82877.1 - 0.054 13.0 4.4 0.13 11.8 4.4 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain YmgB PF10798.8 EGF82877.1 - 0.082 12.7 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR AF-4 PF05110.13 EGF82878.1 - 0.028 12.5 9.4 0.025 12.7 9.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RP-C_C PF11800.8 EGF82878.1 - 0.62 10.1 3.6 0.76 9.8 3.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 EGF82878.1 - 1 8.1 3.4 1.1 8.0 3.4 1.2 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EGF82878.1 - 1.2 8.7 8.8 1.8 8.2 8.8 1.3 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 EGF82878.1 - 6.7 4.7 11.8 7.6 4.5 11.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MPP6 PF10175.9 EGF82879.1 - 2.9e-20 73.1 12.9 2.9e-20 73.1 12.9 1.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Ubiquitin_3 PF14836.6 EGF82879.1 - 0.018 15.0 0.3 0.044 13.8 0.3 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain PNP_phzG_C PF10590.9 EGF82880.1 - 4.8e-21 74.6 2.7 1.1e-20 73.5 0.5 2.5 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EGF82880.1 - 4.3e-19 68.5 0.0 6.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EGF82880.1 - 7.8e-06 26.4 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Molybdopterin_N PF18364.1 EGF82880.1 - 0.39 10.8 2.6 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain MTS PF05175.14 EGF82881.1 - 8.1e-08 32.0 0.1 6e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 EGF82881.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SNARE PF05739.19 EGF82882.1 - 0.00046 20.1 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EGF82882.1 - 0.026 14.3 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Pribosyl_synth PF14572.6 EGF82883.1 - 3.2e-40 138.1 6.0 2.2e-34 119.1 3.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGF82883.1 - 2.8e-37 127.2 0.6 1.3e-36 125.0 0.0 2.3 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGF82883.1 - 8.9e-13 48.1 0.8 6.7e-12 45.2 0.6 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGF82883.1 - 0.013 15.0 0.2 0.022 14.2 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ATP_bind_1 PF03029.17 EGF82884.1 - 1.2e-81 274.1 0.0 1.4e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EGF82884.1 - 0.002 18.0 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGF82884.1 - 0.0062 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGF82884.1 - 0.0085 16.5 0.3 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGF82884.1 - 0.018 15.5 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 EGF82884.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EGF82884.1 - 0.023 14.7 0.0 0.076 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF82884.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGF82884.1 - 0.048 13.9 0.0 0.48 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGF82884.1 - 0.07 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EGF82884.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 EGF82884.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 EGF82884.1 - 0.18 11.6 0.0 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGF82884.1 - 0.19 12.3 0.4 0.52 10.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 EGF82885.1 - 1.1e-16 61.1 9.2 1e-10 41.9 0.8 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF82885.1 - 2.4e-16 58.0 7.9 6.1e-06 25.4 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGF82885.1 - 2.2e-14 52.1 4.5 0.00024 20.8 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGF82885.1 - 4e-12 45.0 1.8 0.002 17.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGF82885.1 - 1.4e-08 34.4 14.0 2.7e-05 23.9 2.1 3.9 4 0 0 4 4 4 3 EF-hand domain pair Dockerin_1 PF00404.18 EGF82885.1 - 0.004 17.3 0.7 1.6 9.0 0.7 3.1 2 1 0 2 2 2 1 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EGF82885.1 - 0.0049 17.2 1.7 0.094 13.0 0.2 2.7 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UCH PF00443.29 EGF82886.1 - 4.8e-17 62.3 8.0 1.3e-16 60.8 0.1 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGF82886.1 - 0.003 18.1 0.9 0.12 13.0 0.0 3.2 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 EGF82886.1 - 0.068 12.7 4.5 3.2 7.2 0.1 2.8 2 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase DUF543 PF04418.12 EGF82887.1 - 4.5e-28 97.1 0.1 5e-28 96.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) UNC-50 PF05216.13 EGF82888.1 - 9e-85 283.7 26.7 1e-84 283.5 26.7 1.0 1 0 0 1 1 1 1 UNC-50 family SCP2 PF02036.17 EGF82889.1 - 9.6e-20 71.0 1.6 1.2e-19 70.6 1.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGF82889.1 - 2.4e-05 24.6 0.2 2.8e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Bac_surface_Ag PF01103.23 EGF82890.1 - 2.9e-45 155.2 0.3 3.7e-45 154.8 0.3 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 EGF82890.1 - 0.03 13.8 0.2 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB DUF321 PF03778.13 EGF82890.1 - 0.065 12.9 0.3 0.21 11.3 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF321) Sec61_beta PF03911.16 EGF82891.1 - 0.0054 16.7 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Sec61beta family PMM PF03332.13 EGF82892.1 - 5.7e-102 340.2 0.3 6.5e-102 340.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGF82892.1 - 8.1e-07 29.0 0.0 1.5e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGF82892.1 - 0.0029 17.2 0.0 0.091 12.3 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 EGF82892.1 - 0.043 14.2 0.1 2.3 8.6 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGF82892.1 - 0.083 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGF82892.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3237 PF11578.8 EGF82893.1 - 0.064 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) F-box-like PF12937.7 EGF82894.1 - 2e-12 46.8 1.2 5.8e-12 45.3 1.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF82894.1 - 2.7e-06 27.1 1.2 2.7e-06 27.1 1.2 2.3 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.6 EGF82894.1 - 0.077 13.1 8.7 52 4.3 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 EGF82894.1 - 0.12 13.0 12.4 80 4.4 0.0 7.3 7 1 0 7 7 7 0 Leucine Rich Repeat PhoLip_ATPase_C PF16212.5 EGF82895.1 - 1.3e-65 221.7 25.9 1.3e-65 221.7 25.9 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGF82895.1 - 3.7e-14 52.2 2.7 3.7e-14 52.2 2.7 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGF82895.1 - 5.9e-12 45.5 0.0 2.2e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGF82895.1 - 1e-10 42.3 0.1 0.0012 19.1 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGF82895.1 - 5.3e-07 29.3 0.0 6.9e-06 25.7 0.0 2.7 2 2 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGF82895.1 - 0.00095 19.0 0.4 0.0035 17.1 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PQ-loop PF04193.14 EGF82896.1 - 4.1e-33 112.9 15.8 1.3e-18 66.5 1.4 3.4 4 0 0 4 4 4 2 PQ loop repeat Kei1 PF08552.11 EGF82896.1 - 0.15 11.9 2.9 2.4 8.0 2.3 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2649 PF10854.8 EGF82896.1 - 0.65 10.3 7.0 2.1 8.7 7.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) DUF1011 PF06237.12 EGF82896.1 - 1.2 9.6 6.3 0.42 11.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1011) AAA PF00004.29 EGF82898.1 - 3.6e-07 30.7 0.0 7.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF82898.1 - 0.00023 21.7 0.0 0.00045 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGF82898.1 - 0.00039 20.0 0.0 0.001 18.6 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGF82898.1 - 0.0013 19.1 0.0 0.0053 17.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EGF82898.1 - 0.0028 17.4 0.0 0.0069 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRTase_1 PF11202.8 EGF82898.1 - 0.0043 16.3 0.0 0.015 14.6 0.0 1.8 3 0 0 3 3 3 1 Phosphoribosyl transferase (PRTase) AAA_22 PF13401.6 EGF82898.1 - 0.0056 16.9 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain TK PF00265.18 EGF82898.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Thymidine kinase AAA_25 PF13481.6 EGF82898.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGF82898.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGF82898.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF82898.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGF82898.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGF82898.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGF82898.1 - 0.22 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SOG2 PF10428.9 EGF82899.1 - 0.00096 18.5 5.9 0.0012 18.2 5.9 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein CNDH2_M PF16869.5 EGF82899.1 - 0.073 13.8 13.0 0.19 12.4 13.0 1.7 1 0 0 1 1 1 0 PF16858 Hid1 PF12722.7 EGF82899.1 - 0.92 7.6 8.1 1.1 7.3 8.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Totivirus_coat PF05518.11 EGF82899.1 - 2.4 6.1 11.6 3.3 5.7 11.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Pex14_N PF04695.13 EGF82899.1 - 9.6 6.8 25.5 21 5.7 25.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M36 PF02128.15 EGF82902.1 - 3.8e-102 342.2 0.3 4.3e-102 342.1 0.3 1.0 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) GATase_2 PF00310.21 EGF82904.1 - 8.5e-169 561.7 0.0 5.3e-147 489.9 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGF82904.1 - 1.2e-154 514.9 0.1 2.9e-153 510.4 0.0 2.3 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGF82904.1 - 1.5e-110 369.1 0.0 1e-109 366.3 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGF82904.1 - 7.6e-85 283.3 4.4 1.2e-84 282.6 4.4 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 EGF82904.1 - 6.7e-23 80.6 0.1 1.4e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EGF82904.1 - 2.2e-16 59.9 0.6 6.3e-12 45.3 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGF82904.1 - 1.5e-08 34.7 0.0 4.7e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGF82904.1 - 1.6e-05 25.4 0.0 7.2e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGF82904.1 - 1.9e-05 24.2 0.0 4.8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGF82904.1 - 6.2e-05 21.9 0.1 6.2e-05 21.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGF82904.1 - 0.00013 21.7 0.1 0.0024 17.5 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGF82904.1 - 0.00017 21.1 0.1 0.00031 20.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGF82904.1 - 0.00042 19.5 0.0 0.00042 19.5 0.0 2.3 3 0 0 3 3 2 1 FAD binding domain FAD_binding_3 PF01494.19 EGF82904.1 - 0.00067 19.0 0.9 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGF82904.1 - 0.0068 15.7 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EGF82904.1 - 0.013 14.7 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.18 EGF82904.1 - 0.016 14.2 0.2 0.038 13.0 0.2 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NAD_binding_7 PF13241.6 EGF82904.1 - 0.032 14.7 0.3 0.32 11.5 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EGF82904.1 - 0.033 13.6 0.0 0.089 12.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGF82904.1 - 0.046 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGF82904.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 EGF82904.1 - 0.085 13.0 0.1 0.69 10.1 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGF82904.1 - 0.11 12.1 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGF82904.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EGF82904.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF667 PF05018.13 EGF82905.1 - 1.7e-93 311.5 1.6 1.9e-93 311.4 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) NARP1 PF12569.8 EGF82906.1 - 1.9e-178 594.6 7.9 2.9e-178 594.0 3.9 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EGF82906.1 - 3.9e-12 46.5 3.9 0.69 10.5 0.1 7.5 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82906.1 - 4.1e-12 45.2 16.6 0.00066 19.6 0.3 9.9 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82906.1 - 7.2e-09 35.2 13.1 0.056 13.7 0.0 7.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82906.1 - 1.3e-07 31.5 3.3 0.16 12.4 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82906.1 - 2.8e-06 27.7 8.9 3.7 8.6 0.0 8.1 9 2 2 11 11 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF82906.1 - 1.9e-05 24.2 17.2 0.015 15.1 0.2 7.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82906.1 - 3e-05 24.2 5.8 0.34 11.2 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF82906.1 - 4e-05 24.0 7.2 3 8.7 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82906.1 - 8e-05 22.2 0.1 0.29 10.9 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.6 EGF82906.1 - 0.00015 21.6 0.2 0.027 14.5 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF82906.1 - 0.00015 21.8 3.5 1.6 8.9 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82906.1 - 0.0002 21.9 1.5 4.3 8.1 0.0 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF82906.1 - 0.0007 19.8 11.2 1.5 9.1 0.1 6.3 6 1 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EGF82906.1 - 0.011 15.5 2.2 0.83 9.3 0.1 3.6 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_15 PF13429.6 EGF82906.1 - 0.012 14.9 0.5 0.053 12.7 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Metallophos_3 PF14582.6 EGF82906.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily TBPIP PF07106.13 EGF82906.1 - 0.075 13.0 0.0 23 5.0 0.0 3.2 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain Fis1_TPR_C PF14853.6 EGF82906.1 - 0.24 11.5 7.7 9.2 6.4 0.3 5.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat PSGP PF07276.11 EGF82906.1 - 0.89 10.1 2.7 2 9.0 2.7 1.6 1 0 0 1 1 1 0 Apopolysialoglycoprotein (PSGP) MIT PF04212.18 EGF82906.1 - 3.2 7.9 8.0 0.61 10.2 0.2 4.0 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain SlyX PF04102.12 EGF82911.1 - 0.046 14.3 0.8 0.82 10.3 0.2 2.3 1 1 0 2 2 2 0 SlyX DUF3368 PF11848.8 EGF82911.1 - 0.11 12.3 0.6 0.66 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Peptidase_S41 PF03572.18 EGF82912.1 - 1.9e-11 43.8 0.0 4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 EF1G PF00647.19 EGF82914.1 - 0.032 14.3 0.4 0.064 13.3 0.4 1.6 1 1 0 1 1 1 0 Elongation factor 1 gamma, conserved domain SAWADEE PF16719.5 EGF82914.1 - 0.084 12.9 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 SAWADEE domain Methyltransf_22 PF13383.6 EGF82915.1 - 5.6e-25 88.4 0.1 7.4e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EGF82915.1 - 1.1e-08 35.3 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Acyl_transf_3 PF01757.22 EGF82916.1 - 4.6e-15 55.5 26.5 4.5e-14 52.3 26.5 2.0 1 1 0 1 1 1 1 Acyltransferase family TMPIT PF07851.13 EGF82917.1 - 1.2e-78 264.7 5.4 1.5e-78 264.3 5.4 1.1 1 0 0 1 1 1 1 TMPIT-like protein eRF1_2 PF03464.15 EGF82919.1 - 2.2e-45 154.3 0.1 3.4e-45 153.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGF82919.1 - 1.1e-37 129.0 0.1 2.1e-37 128.1 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGF82919.1 - 1.8e-21 76.5 0.0 3.5e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EGF82919.1 - 5.3e-09 36.5 0.0 8.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EGF82919.1 - 1.1e-08 35.5 0.1 1.7e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 EGF82919.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Hist_deacetyl PF00850.19 EGF82920.1 - 8.7e-76 255.3 0.0 1.1e-75 255.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Aa_trans PF01490.18 EGF82921.1 - 1.2e-82 277.9 27.2 1.3e-82 277.7 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGF82921.1 - 1.2e-10 41.1 12.5 1.2e-10 41.1 12.5 1.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family SUI1 PF01253.22 EGF82922.1 - 5.8e-26 90.8 0.4 8.1e-26 90.4 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 EGF82922.1 - 0.058 13.7 0.1 0.082 13.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) ECH_2 PF16113.5 EGF82923.1 - 1.3e-120 402.9 0.0 2e-120 402.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGF82923.1 - 3.1e-28 98.8 0.0 3.2e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Cnl2_NKP2 PF09447.10 EGF82923.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein PseudoU_synth_1 PF01416.20 EGF82924.1 - 4.7e-07 30.2 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridine synthase Pkinase PF00069.25 EGF82926.1 - 5.6e-53 180.0 0.1 6.8e-53 179.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82926.1 - 5.8e-30 104.4 0.0 7.6e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF82926.1 - 0.0023 17.3 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGF82926.1 - 0.0043 16.4 0.1 0.0071 15.7 0.1 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGF82926.1 - 0.02 14.5 0.1 6.2 6.4 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EGF82926.1 - 0.037 13.6 0.0 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EGF82926.1 - 0.046 13.7 0.0 0.39 10.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ion_trans PF00520.31 EGF82927.1 - 1.3e-14 54.0 14.5 2.4e-14 53.2 14.5 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGF82927.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1580 PF07618.11 EGF82927.1 - 0.31 10.7 1.4 7.7 6.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) FHA PF00498.26 EGF82928.1 - 8.7e-14 51.6 0.0 2.3e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EGF82928.1 - 9.4e-10 38.1 11.7 2e-09 37.0 11.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGF82928.1 - 1e-06 29.0 10.8 1.9e-06 28.1 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EGF82928.1 - 0.0004 20.6 0.0 0.0019 18.5 0.0 2.2 2 0 0 2 2 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 EGF82928.1 - 0.0015 18.5 3.1 0.0036 17.3 3.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGF82928.1 - 0.0021 18.0 8.6 0.0046 16.9 8.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGF82928.1 - 0.0036 17.6 6.7 0.0095 16.2 6.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGF82928.1 - 0.012 15.5 12.6 0.023 14.5 12.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGF82928.1 - 0.045 13.6 9.5 0.081 12.8 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF82928.1 - 0.071 13.0 11.9 0.13 12.1 11.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EGF82928.1 - 0.4 10.6 7.8 0.77 9.7 7.8 1.5 1 0 0 1 1 1 0 PHD-finger TPR_1 PF00515.28 EGF82929.1 - 6.3e-17 60.6 0.5 1.4e-06 27.8 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82929.1 - 3.3e-16 58.0 0.5 6.6e-06 25.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF82929.1 - 7.7e-11 42.1 0.1 2.4e-08 34.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82929.1 - 1.3e-10 40.6 0.1 0.00071 19.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.24 EGF82929.1 - 2.4e-10 40.2 0.1 5e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 PB1 domain TPR_6 PF13174.6 EGF82929.1 - 1.3e-09 38.1 0.2 0.43 11.3 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGF82929.1 - 3e-07 31.0 0.0 0.003 18.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EGF82929.1 - 0.00026 21.0 1.1 0.12 12.5 0.3 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 EGF82929.1 - 0.00035 21.2 0.0 5 8.2 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF82929.1 - 0.00036 20.7 0.1 0.93 9.8 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGF82929.1 - 0.00071 20.0 0.5 0.0088 16.5 0.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82929.1 - 0.002 17.8 0.3 0.13 11.9 0.0 3.4 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 EGF82929.1 - 0.0026 17.9 0.0 0.39 10.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82929.1 - 0.0027 17.6 0.8 20 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGF82929.1 - 0.22 11.4 0.8 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.21 EGF82931.1 - 4.5e-36 124.0 2.8 4.5e-36 124.0 2.8 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 LMWPc PF01451.21 EGF82932.1 - 4.4e-37 127.6 0.0 5.1e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 EGF82933.1 - 3.7e-70 236.3 0.0 4.2e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82933.1 - 2.9e-31 108.7 0.0 3.7e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF82933.1 - 0.012 14.6 0.0 0.21 10.5 0.0 2.2 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EGF82933.1 - 0.044 13.1 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EGF82933.1 - 0.056 13.4 0.0 0.2 11.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Spb1_C PF07780.12 EGF82934.1 - 3.7e-66 222.8 29.7 3.7e-66 222.8 29.7 3.7 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EGF82934.1 - 6.1e-54 182.8 0.7 9.4e-54 182.2 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGF82934.1 - 1.8e-32 112.5 11.4 1.8e-32 112.5 11.4 5.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3381) TIP41 PF04176.13 EGF82935.1 - 1.4e-65 220.0 0.0 1.6e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family PCSK9_C3 PF18463.1 EGF82935.1 - 0.0063 16.7 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Metallophos PF00149.28 EGF82936.1 - 3.3e-09 37.5 0.7 7.3e-09 36.4 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGF82936.1 - 2.2e-05 24.7 0.0 7.9e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RecO_N_2 PF13114.6 EGF82936.1 - 0.14 11.9 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 RecO N terminal Pkinase PF00069.25 EGF82937.1 - 1.9e-63 214.3 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82937.1 - 1.8e-26 93.0 0.0 2.9e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF82937.1 - 0.0081 15.5 0.1 0.016 14.6 0.1 1.6 1 1 0 1 1 1 1 Kinase-like RLI PF04068.15 EGF82939.1 - 9.1e-15 54.2 0.1 2e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribo_biogen_C PF04034.13 EGF82939.1 - 1.3e-14 54.1 0.4 1.5e-11 44.1 0.0 2.6 3 0 0 3 3 3 2 Ribosome biogenesis protein, C-terminal CheR PF01739.18 EGF82940.1 - 0.23 10.9 0.0 0.33 10.4 0.0 1.1 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain SH3_9 PF14604.6 EGF82941.1 - 1.9e-05 24.4 0.1 3.5e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF82941.1 - 0.0027 17.3 0.3 0.0052 16.4 0.3 1.4 1 0 0 1 1 1 1 SH3 domain Haemagg_act PF05860.13 EGF82942.1 - 0.15 11.9 6.3 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 haemagglutination activity domain Nramp PF01566.18 EGF82943.1 - 9.8e-114 380.0 22.1 9.8e-114 380.0 22.1 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein WD40 PF00400.32 EGF82944.1 - 3.5e-17 62.5 6.7 0.0064 17.3 0.1 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82944.1 - 1.6e-07 31.5 0.0 0.46 10.8 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 EGF82944.1 - 0.045 13.4 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 CNH domain Marek_SORF3 PF07153.11 EGF82944.1 - 0.081 12.3 0.0 0.65 9.3 0.0 2.1 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein BBS2_Mid PF14783.6 EGF82944.1 - 0.082 13.0 0.0 3.9 7.6 0.0 2.8 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Arf PF00025.21 EGF82945.1 - 7.4e-79 263.2 0.2 8.6e-79 263.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF82945.1 - 5.4e-14 52.4 0.0 7.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGF82945.1 - 5.4e-13 48.8 0.9 4.3e-09 36.0 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGF82945.1 - 5.9e-13 48.7 0.0 6.4e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGF82945.1 - 6.1e-13 48.6 0.0 7.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGF82945.1 - 2.7e-10 40.0 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGF82945.1 - 1.5e-05 25.0 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGF82945.1 - 0.0099 15.2 0.4 0.028 13.7 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TPH PF13868.6 EGF82946.1 - 5.4 5.4 95.9 0.033 12.7 76.8 2.1 1 1 1 2 2 2 0 Trichohyalin-plectin-homology domain NAD_Gly3P_dh_N PF01210.23 EGF82946.1 - 8.2 6.4 7.9 0.54 10.2 0.8 2.5 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PPR_3 PF13812.6 EGF82947.1 - 7.4e-07 29.2 3.2 3.3 7.9 0.2 5.5 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 EGF82947.1 - 7.6e-07 29.0 7.2 0.19 12.1 0.0 7.0 8 0 0 8 8 8 2 PPR repeat PPR_2 PF13041.6 EGF82947.1 - 0.0014 18.7 0.2 14 6.0 0.0 5.0 5 1 0 5 5 5 1 PPR repeat family TPR_8 PF13181.6 EGF82947.1 - 0.019 15.1 8.6 9.3 6.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1748 PF08520.10 EGF82947.1 - 0.023 14.6 0.3 0.098 12.6 0.2 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) MA3 PF02847.17 EGF82947.1 - 0.047 13.7 0.2 2 8.5 0.0 3.3 4 0 0 4 4 4 0 MA3 domain Tubulin PF00091.25 EGF82948.1 - 2.7e-68 230.1 0.0 3.8e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF82948.1 - 8.5e-52 174.6 0.0 1.4e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGF82948.1 - 0.00079 19.1 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain HhH-GPD PF00730.25 EGF82949.1 - 5.9e-21 75.0 0.0 1.1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGF82949.1 - 1.8e-09 37.0 0.1 5.9e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EGF82949.1 - 0.024 15.0 6.6 0.024 15.0 6.6 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III NUDIX_4 PF14815.6 EGF82949.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 NUDIX domain DDE_Tnp_1_6 PF13751.6 EGF82949.1 - 0.2 11.9 5.1 0.47 10.7 5.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain Bestrophin PF01062.21 EGF82950.1 - 5e-40 137.7 0.0 1.4e-39 136.3 0.0 1.6 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 EGF82951.1 - 1.9e-45 155.5 0.4 2.4e-45 155.2 0.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CstA_5TM PF13722.6 EGF82951.1 - 3.3 8.1 6.6 0.3 11.5 0.6 2.2 3 0 0 3 3 3 0 5TM C-terminal transporter carbon starvation CstA Smg8_Smg9 PF10220.9 EGF82952.1 - 0.00049 18.6 0.0 0.00096 17.6 0.0 1.4 1 0 0 1 1 1 1 Smg8_Smg9 ABC_tran PF00005.27 EGF82952.1 - 0.065 13.8 0.1 0.37 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 EGF82952.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGF82952.1 - 0.31 11.1 1.9 0.44 10.6 0.3 2.1 2 0 0 2 2 2 0 Dynamin family Rpr2 PF04032.16 EGF82954.1 - 2.7e-09 37.2 8.9 3.3e-09 36.9 6.7 2.4 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 EGF82954.1 - 3.9 7.5 5.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal DAD PF02109.16 EGF82955.1 - 2.7e-38 130.6 4.2 3.5e-38 130.2 4.2 1.2 1 0 0 1 1 1 1 DAD family TMEM154 PF15102.6 EGF82955.1 - 0.23 11.3 5.1 0.3 11.0 5.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 EGF82955.1 - 0.4 10.9 9.8 0.52 10.5 9.8 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF3439 PF11921.8 EGF82955.1 - 0.68 9.9 12.9 0.96 9.4 12.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Coatomer_WDAD PF04053.14 EGF82956.1 - 2.3e-167 557.6 0.0 9.2e-166 552.3 0.0 2.3 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGF82956.1 - 2.4e-39 132.6 14.1 4.2e-08 33.7 0.3 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF82956.1 - 9.9e-11 41.8 0.2 0.06 13.6 0.0 6.8 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGF82956.1 - 8.8e-05 22.5 0.1 6.7 6.8 0.0 4.8 1 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EGF82956.1 - 0.0033 16.1 3.2 1.6 7.3 0.1 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 CDC24_OB3 PF17244.2 EGF82957.1 - 3.9e-46 157.6 2.7 5.8e-46 157.0 1.3 1.9 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 EGF82957.1 - 1.1e-19 71.3 0.4 2.1e-19 70.3 0.4 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 Rep_fac-A_C PF08646.10 EGF82957.1 - 0.00033 20.4 0.1 0.00069 19.4 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 EGF82957.1 - 0.0024 17.8 0.0 6.9 6.7 0.0 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Pribosyltran PF00156.27 EGF82958.1 - 7.4e-13 48.3 0.1 1.8e-12 47.0 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EGF82958.1 - 0.012 15.1 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Velvet PF11754.8 EGF82959.1 - 5e-22 79.1 0.5 6.1e-21 75.5 1.1 2.3 2 1 0 2 2 2 1 Velvet factor Adaptin_binding PF10199.9 EGF82961.1 - 3.7e-10 40.5 1.4 4.8e-09 36.9 1.4 2.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Unstab_antitox PF09720.10 EGF82961.1 - 0.029 14.4 2.2 0.044 13.8 0.3 2.3 2 0 0 2 2 2 0 Putative addiction module component Pro_isomerase PF00160.21 EGF82962.1 - 1e-41 142.9 0.0 1.2e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosom_S12_S23 PF00164.25 EGF82963.1 - 8.6e-39 131.7 1.3 1.1e-38 131.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 EGF82963.1 - 0.033 14.9 0.0 0.066 13.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 LDcluster4 PF18306.1 EGF82963.1 - 0.044 13.4 0.1 0.14 11.8 0.1 1.7 1 1 1 2 2 2 0 SLOG cluster4 family Thioredoxin PF00085.20 EGF82964.1 - 4.4e-30 103.7 0.2 2.1e-28 98.3 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 EGF82964.1 - 1.2e-05 25.7 0.1 3.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGF82964.1 - 2.7e-05 24.4 0.2 0.012 15.9 0.0 3.7 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 EGF82964.1 - 0.00027 20.9 1.7 0.036 14.0 0.1 3.0 3 0 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 EGF82964.1 - 0.002 17.5 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGF82964.1 - 0.033 14.3 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like HEAT PF02985.22 EGF82965.1 - 2.1e-10 40.0 12.1 5.6 7.5 0.0 10.2 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 EGF82965.1 - 9.7e-10 38.7 2.6 0.14 12.5 0.1 6.2 5 1 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 EGF82965.1 - 7.1e-07 29.6 4.5 15 6.2 0.1 8.4 9 0 0 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGF82965.1 - 0.00031 21.3 0.3 2.1 9.0 0.0 5.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGF82965.1 - 0.00077 19.5 13.2 3.5 7.6 0.1 5.7 7 0 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EGF82965.1 - 0.0097 15.1 0.7 0.2 10.8 0.1 2.9 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FPL PF09758.9 EGF82965.1 - 0.058 13.4 1.3 0.67 10.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF3385 PF11865.8 EGF82965.1 - 0.075 12.9 2.5 2.1 8.2 1.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) LRR_6 PF13516.6 EGF82966.1 - 8.3e-17 59.8 16.0 0.0011 18.9 1.6 6.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_8 PF13855.6 EGF82966.1 - 8e-06 25.5 8.6 0.18 11.6 0.3 4.9 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EGF82966.1 - 0.0017 18.7 15.5 0.013 15.9 0.2 5.0 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF82966.1 - 0.0019 18.5 9.7 14 6.7 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich Repeat zf-CCCH PF00642.24 EGF82967.1 - 1e-08 34.9 29.5 0.00079 19.3 1.1 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGF82967.1 - 8.4e-08 32.0 31.1 0.00074 19.5 0.6 5.6 5 1 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EGF82967.1 - 6.7e-05 23.6 21.3 0.017 15.8 1.8 4.6 1 1 2 4 4 4 4 Torus domain zf-CCCH_3 PF15663.5 EGF82967.1 - 0.027 14.7 2.8 0.027 14.7 2.8 3.4 1 1 2 3 3 3 0 Zinc-finger containing family zf-C3H1 PF10650.9 EGF82967.1 - 0.99 9.2 17.4 2.7 7.8 0.3 4.2 4 0 0 4 4 4 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 EGF82967.1 - 8 7.1 23.7 1.1 9.8 0.2 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger CSTF2_hinge PF14327.6 EGF82968.1 - 2.9e-19 69.3 1.7 2.9e-19 69.3 1.7 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EGF82968.1 - 1.1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EGF82968.1 - 3.4e-11 42.5 13.5 6.2e-11 41.7 13.5 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal partial_CstF PF15861.5 EGF82968.1 - 0.027 14.2 1.0 0.073 12.9 1.0 1.7 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain RRM_occluded PF16842.5 EGF82968.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif ASF1_hist_chap PF04729.13 EGF82969.1 - 3.3e-56 189.5 0.1 3.7e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Hydrolase_4 PF12146.8 EGF82970.1 - 2.1e-14 53.4 0.0 3.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF82970.1 - 8.1e-14 52.7 0.0 1e-13 52.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGF82970.1 - 6.4e-12 45.7 0.0 5.7e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EGF82970.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 EGF82970.1 - 2.3e-05 24.6 0.0 3.8e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EGF82970.1 - 0.0026 17.6 0.0 0.007 16.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EGF82970.1 - 0.0099 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 EGF82970.1 - 0.017 14.1 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EGF82970.1 - 0.018 14.8 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 EGF82970.1 - 0.1 12.1 0.2 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF4164 PF13747.6 EGF82971.1 - 0.16 12.3 3.1 0.45 10.8 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) Muted PF14942.6 EGF82971.1 - 7.2 6.9 10.2 1.1 9.5 0.1 3.6 4 0 0 4 4 4 0 Organelle biogenesis, Muted-like protein Choline_transpo PF04515.12 EGF82972.1 - 1.5e-80 270.8 26.9 1.5e-80 270.8 26.9 2.5 1 1 2 3 3 3 1 Plasma-membrane choline transporter DUF3433 PF11915.8 EGF82972.1 - 0.85 10.1 11.8 0.04 14.4 4.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) Yip1 PF04893.17 EGF82972.1 - 1.7 8.4 40.2 0.81 9.4 1.8 3.3 2 1 1 3 3 3 0 Yip1 domain INTS2 PF14750.6 EGF82973.1 - 9.3e-43 146.0 23.1 3.2e-40 137.6 20.8 3.3 2 1 0 2 2 2 2 Integrator complex subunit 2 PSS PF03034.15 EGF82974.1 - 2.3e-108 362.1 20.9 2.9e-108 361.8 20.9 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Myb_DNA-binding PF00249.31 EGF82975.1 - 2.6e-21 75.5 2.9 3.1e-11 43.3 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF82975.1 - 7.4e-20 71.0 0.3 2.1e-08 34.3 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGF82975.1 - 2.8e-07 30.3 0.0 0.00046 20.0 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like DUF3580 PF12117.8 EGF82975.1 - 0.029 14.6 2.2 0.05 13.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) SANT_DAMP1_like PF16282.5 EGF82975.1 - 0.11 12.8 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Ammonium_transp PF00909.21 EGF82976.1 - 3e-115 385.1 28.1 3.5e-115 384.9 28.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CD47 PF04549.14 EGF82976.1 - 0.015 15.5 1.4 0.015 15.5 1.4 2.1 2 0 0 2 2 2 0 CD47 transmembrane region MFS_1 PF07690.16 EGF82978.1 - 1.2e-18 67.2 35.4 1.4e-09 37.4 9.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily NOPS PF08075.11 EGF82978.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 NOPS (NUC059) domain CRPA PF05745.11 EGF82978.1 - 3 7.8 5.7 9.5 6.2 5.7 1.8 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) RRM_occluded PF16842.5 EGF82979.1 - 0.0028 17.5 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_1 PF00076.22 EGF82979.1 - 0.0043 16.8 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF761 PF05553.11 EGF82980.1 - 0.029 13.9 0.2 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 Cotton fibre expressed protein AMP-binding PF00501.28 EGF82981.1 - 9.9e-48 162.8 0.5 2.5e-24 85.7 0.0 4.0 3 1 0 3 3 3 3 AMP-binding enzyme DIE2_ALG10 PF04922.12 EGF82982.1 - 4.4e-103 345.6 23.8 4.6e-56 190.8 5.1 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family NDUF_B12 PF08122.12 EGF82982.1 - 0.098 12.7 0.4 2.6 8.2 0.1 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family SAM_decarbox PF01536.16 EGF82983.1 - 4.6e-114 381.1 0.0 3.2e-108 361.9 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase F-box-like PF12937.7 EGF82983.1 - 0.00022 21.0 0.3 0.00051 19.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like RPEL PF02755.15 EGF82983.1 - 0.00081 19.0 8.2 1.3 8.8 0.4 4.2 4 0 0 4 4 4 2 RPEL repeat F-box PF00646.33 EGF82983.1 - 0.024 14.5 0.3 0.084 12.8 0.3 2.0 1 0 0 1 1 1 0 F-box domain RRM_1 PF00076.22 EGF82984.1 - 8.1e-09 35.2 0.1 7.4e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGF82984.1 - 0.0003 20.8 1.0 0.021 14.9 0.1 3.7 3 1 0 3 3 3 1 RNA binding motif Pkinase PF00069.25 EGF82985.1 - 2.6e-64 217.1 0.0 3.5e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF82985.1 - 5.2e-33 114.4 0.0 7e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF82985.1 - 0.0056 16.1 0.3 0.0094 15.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF82985.1 - 0.0077 15.2 0.1 0.037 13.0 0.0 1.9 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGF82985.1 - 0.045 13.7 0.5 0.15 12.0 0.1 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGF82985.1 - 0.087 12.1 0.0 0.92 8.8 0.0 2.0 1 1 1 2 2 2 0 Kinase-like DnaJ_C PF01556.18 EGF82986.1 - 1.1e-44 152.1 0.1 1.6e-44 151.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGF82986.1 - 1.4e-24 86.0 2.7 2.3e-24 85.3 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGF82986.1 - 7.8e-15 55.0 19.8 1.3e-14 54.3 19.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGF82986.1 - 0.048 13.6 10.3 1.4 9.0 1.1 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGF82986.1 - 7.2 6.7 12.6 4 7.5 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA U3_assoc_6 PF08640.11 EGF82987.1 - 5.5e-31 106.5 1.2 5.5e-31 106.5 1.2 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EGF82987.1 - 2.1e-05 25.0 0.0 0.043 14.7 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EGF82987.1 - 0.012 14.7 0.4 0.34 10.0 0.2 2.1 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 EGF82987.1 - 0.017 15.5 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82987.1 - 0.056 13.6 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat KN_motif PF12075.8 EGF82987.1 - 0.15 11.8 0.2 0.37 10.6 0.2 1.6 1 0 0 1 1 1 0 KN motif Methyltransf_8 PF05148.15 EGF82988.1 - 6.5e-86 287.7 0.1 9.1e-86 287.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGF82988.1 - 1.3e-05 25.8 0.1 9.6e-05 23.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF82988.1 - 0.00024 21.8 0.1 0.025 15.3 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF82988.1 - 0.025 13.9 0.1 0.21 10.9 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3836 PF12930.7 EGF82989.1 - 0.019 14.7 0.9 0.038 13.8 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF3836) TPR_1 PF00515.28 EGF82990.1 - 5e-11 41.9 3.1 0.00038 20.2 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGF82990.1 - 1.1e-08 34.5 2.2 0.011 15.8 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF82990.1 - 5.6e-06 26.7 0.2 1.9 9.5 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF82990.1 - 2.6e-05 24.6 1.2 0.018 15.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF82990.1 - 0.00076 19.5 2.0 6.1 7.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF82990.1 - 0.00083 19.5 2.5 0.00083 19.5 2.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGF82990.1 - 0.043 14.1 0.7 0.12 12.7 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF82990.1 - 0.059 13.4 1.0 1.4 9.1 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGF82990.1 - 0.22 12.0 2.9 8.8 7.0 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGF82990.1 - 2.5 7.9 7.3 6.5 6.5 0.1 3.5 1 1 2 3 3 3 0 TPR repeat PIG-L PF02585.17 EGF82991.1 - 1.3e-13 51.7 2.5 1.8e-06 28.6 0.6 2.3 1 1 1 2 2 2 2 GlcNAc-PI de-N-acetylase Mito_carr PF00153.27 EGF82992.1 - 1.8e-25 88.7 6.1 3.8e-12 45.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF82992.1 - 0.00055 19.2 0.3 0.0018 17.5 0.2 2.0 1 1 1 2 2 2 1 Gammaproteobacterial serine protease NAD_binding_2 PF03446.15 EGF82993.1 - 3.1e-18 66.4 0.0 6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGF82993.1 - 2e-10 41.0 0.1 3.6e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PDH PF02153.17 EGF82993.1 - 0.022 13.8 0.1 0.05 12.6 0.0 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase RhoGAP PF00620.27 EGF82994.1 - 4e-51 172.8 0.2 9.4e-51 171.6 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 EGF82994.1 - 2e-12 47.6 0.2 4.3e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGF82994.1 - 2.1e-08 34.5 0.1 5.5e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain WW PF00397.26 EGF82994.1 - 6.5e-08 32.5 4.7 6.5e-08 32.5 4.7 1.8 2 0 0 2 2 2 1 WW domain PH_11 PF15413.6 EGF82994.1 - 0.0026 18.2 0.3 0.0071 16.8 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EGF82994.1 - 0.0041 16.9 0.5 0.0085 15.9 0.5 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EGF82994.1 - 0.02 15.2 0.3 0.056 13.7 0.3 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 EGF82994.1 - 0.027 14.8 0.2 0.066 13.6 0.2 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region 7tm_1 PF00001.21 EGF82995.1 - 0.093 12.0 18.0 0.25 10.7 2.5 2.9 2 2 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Methyltr_RsmB-F PF01189.17 EGF82997.1 - 5.6e-16 58.8 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EGF82997.1 - 0.00067 19.5 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Lipase_GDSL_lke PF16255.5 EGF82997.1 - 0.016 14.6 0.0 0.048 13.0 0.0 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Chalcone_2 PF16035.5 EGF82998.1 - 4.4e-35 121.3 0.0 7.6e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EGF82998.1 - 2.1e-07 31.2 0.0 0.0077 16.4 0.0 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 EGF82998.1 - 0.00065 19.2 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase RcbX PF02341.15 EGF82998.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 RbcX protein ABC_tran PF00005.27 EGF82999.1 - 2.7e-48 163.9 0.0 1.4e-22 80.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGF82999.1 - 1.3e-23 82.8 3.3 1.3e-23 82.8 3.3 2.0 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EGF82999.1 - 2.9e-19 70.0 1.5 0.00056 19.8 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGF82999.1 - 4.6e-11 42.6 6.0 0.022 14.2 0.0 5.0 4 1 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGF82999.1 - 1.6e-08 34.2 0.1 0.0072 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGF82999.1 - 3.2e-08 33.8 0.2 0.0022 18.1 0.0 4.0 2 1 1 3 3 3 2 Dynamin family AAA_15 PF13175.6 EGF82999.1 - 1.1e-07 31.9 2.0 0.0091 15.7 1.6 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 EGF82999.1 - 8.4e-07 29.5 0.0 0.061 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGF82999.1 - 9.3e-07 29.1 0.0 0.012 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGF82999.1 - 1.9e-06 27.9 1.6 0.025 14.5 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EGF82999.1 - 1.1e-05 25.5 0.0 0.048 13.7 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGF82999.1 - 1.3e-05 25.5 0.0 0.24 11.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGF82999.1 - 3.8e-05 24.3 13.7 0.03 14.8 0.5 3.7 4 1 0 4 4 3 2 AAA domain AAA_24 PF13479.6 EGF82999.1 - 3.8e-05 23.5 0.0 0.35 10.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EGF82999.1 - 9.3e-05 22.5 0.0 0.24 11.5 0.0 3.5 4 1 1 5 5 2 1 AAA domain AAA_25 PF13481.6 EGF82999.1 - 0.00011 21.9 0.0 0.45 10.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EGF82999.1 - 0.00012 22.6 0.0 0.4 11.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGF82999.1 - 0.00019 21.4 0.0 0.59 10.0 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_5 PF07728.14 EGF82999.1 - 0.0002 21.3 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGF82999.1 - 0.00022 21.5 0.0 0.85 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGF82999.1 - 0.00034 19.8 0.0 0.1 11.6 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EGF82999.1 - 0.00063 20.1 1.2 2.3 8.6 0.0 3.2 3 1 0 3 3 3 2 RNA helicase AAA PF00004.29 EGF82999.1 - 0.00068 20.1 0.0 1.6 9.2 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGF82999.1 - 0.00098 18.9 0.0 0.18 11.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGF82999.1 - 0.0018 17.5 0.0 1.1 8.4 0.0 2.6 2 1 0 2 2 2 1 NB-ARC domain AAA_27 PF13514.6 EGF82999.1 - 0.0024 17.5 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGF82999.1 - 0.0028 17.2 0.1 2.4 7.6 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region Pox_A32 PF04665.12 EGF82999.1 - 0.0041 16.6 0.7 0.3 10.5 0.0 2.8 3 0 0 3 3 3 1 Poxvirus A32 protein TsaE PF02367.17 EGF82999.1 - 0.0043 17.1 0.0 1.2 9.1 0.0 3.0 2 1 1 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGF82999.1 - 0.0046 16.9 0.0 0.88 9.5 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_17 PF13207.6 EGF82999.1 - 0.0056 17.1 0.0 6.8 7.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 EGF82999.1 - 0.0058 15.8 0.1 3.3 6.8 0.0 2.8 2 2 1 3 3 3 1 G-protein alpha subunit ATP_bind_1 PF03029.17 EGF82999.1 - 0.0062 16.4 0.2 1.1 9.0 0.0 2.7 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 EGF82999.1 - 0.013 15.2 0.2 8 6.0 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EGF82999.1 - 0.016 15.5 0.0 3.3 8.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGF82999.1 - 0.018 14.4 0.0 0.63 9.3 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family VirE PF05272.11 EGF82999.1 - 0.021 14.6 0.1 3 7.5 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E PduV-EutP PF10662.9 EGF82999.1 - 0.032 14.0 0.1 9.4 6.0 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGF82999.1 - 0.037 13.3 0.0 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 EGF82999.1 - 0.04 13.8 0.1 3 7.7 0.1 2.8 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 EGF82999.1 - 0.04 12.9 0.2 8.7 5.2 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cas_Cas1 PF01867.16 EGF82999.1 - 0.078 12.1 0.4 0.16 11.0 0.4 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas1 DUF87 PF01935.17 EGF82999.1 - 0.081 13.0 2.5 10 6.1 0.0 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 EGF82999.1 - 0.1 12.3 3.3 1.3 8.7 0.0 3.3 3 0 0 3 3 3 0 Cytidylate kinase Mg_chelatase PF01078.21 EGF82999.1 - 0.1 12.0 0.1 3.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGF82999.1 - 0.12 12.1 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Guanylate_kin PF00625.21 EGF82999.1 - 0.13 11.9 0.9 16 5.1 0.0 2.7 3 0 0 3 3 2 0 Guanylate kinase MutS_V PF00488.21 EGF82999.1 - 0.15 12.0 0.3 22 5.0 0.0 2.6 2 0 0 2 2 2 0 MutS domain V ABC_tran_CTD PF16326.5 EGF82999.1 - 5.8 7.2 7.2 1.6 9.0 1.7 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain CAMSAP_CKK PF08683.11 EGF83000.1 - 7.7e-28 97.0 0.0 1.8e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 EGF83000.1 - 3.1e-10 39.8 0.2 2e-08 33.9 0.0 3.0 2 0 0 2 2 2 1 CAMSAP CH domain CH PF00307.31 EGF83000.1 - 0.039 14.1 0.0 5.1 7.3 0.0 3.0 2 0 0 2 2 2 0 Calponin homology (CH) domain PIG-X PF08320.12 EGF83001.1 - 1.5e-20 74.0 0.1 4.2e-19 69.3 0.1 2.3 1 1 0 1 1 1 1 PIG-X / PBN1 PBD PF00786.28 EGF83003.1 - 1.6e-16 60.4 0.1 3.7e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 EGF83003.1 - 2e-16 59.9 0.0 3.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Prefoldin PF02996.17 EGF83004.1 - 6.1e-31 106.8 2.2 8e-31 106.5 2.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 EGF83004.1 - 0.0036 17.5 1.5 0.0048 17.1 0.2 1.7 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_2 PF01920.20 EGF83004.1 - 0.011 15.7 3.3 0.042 13.8 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit KxDL PF10241.9 EGF83004.1 - 0.36 11.1 3.8 0.57 10.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein Lge1 PF11488.8 EGF83004.1 - 0.37 11.0 4.9 0.36 11.0 0.7 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF1664 PF07889.12 EGF83004.1 - 0.38 10.8 2.4 1.5 8.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FYVE PF01363.21 EGF83005.1 - 3.8e-18 65.4 13.9 6.9e-18 64.6 13.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger Myb_DNA-binding PF00249.31 EGF83005.1 - 6.7e-05 23.0 0.5 0.00016 21.8 0.3 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF83005.1 - 0.002 18.3 0.1 0.0051 17.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EGF83005.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain FYVE_2 PF02318.16 EGF83005.1 - 0.26 11.5 8.7 0.58 10.4 8.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger CCDC66 PF15236.6 EGF83007.1 - 1.4e-05 24.9 27.0 1.4e-05 24.9 27.0 5.0 5 0 0 5 5 5 1 Coiled-coil domain-containing protein 66 ARID PF01388.21 EGF83008.1 - 1.1e-13 51.7 0.0 1.1e-13 51.7 0.0 3.6 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EGF83008.1 - 0.023 14.0 0.3 0.023 14.0 0.3 3.0 2 1 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Ribosomal_L31 PF01197.18 EGF83009.1 - 9e-05 22.6 0.3 0.00023 21.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L31 Mitoc_L55 PF09776.9 EGF83009.1 - 0.0012 18.6 0.2 0.0075 16.0 0.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L55 Complex1_30kDa PF00329.19 EGF83010.1 - 8.7e-47 158.7 0.0 1.1e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HSP70 PF00012.20 EGF83011.1 - 1.5e-253 842.5 8.0 1.7e-253 842.3 8.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF83011.1 - 3.9e-18 65.3 1.1 3.9e-17 62.1 0.7 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EGF83011.1 - 0.01 15.1 0.9 0.067 12.4 0.2 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EGF83011.1 - 0.036 14.5 7.6 2.2 8.7 0.1 3.8 3 2 0 3 3 3 0 Cell division protein FtsA Phe_tRNA-synt_N PF02912.18 EGF83011.1 - 0.067 13.1 0.4 0.26 11.2 0.3 2.1 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF1542 PF07564.11 EGF83011.1 - 0.084 13.0 0.6 0.3 11.2 0.6 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Sec2p PF06428.11 EGF83011.1 - 1.2 9.1 5.5 11 6.0 0.1 2.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p zf-Tim10_DDP PF02953.15 EGF83012.1 - 3.4e-20 71.4 0.7 4e-20 71.2 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Staph_opine_DH PF10100.9 EGF83012.1 - 0.1 11.2 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase CUE PF02845.16 EGF83013.1 - 0.0023 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain Pox_RNA_Pol_19 PF05320.12 EGF83013.1 - 0.23 11.4 4.7 0.3 11.0 4.7 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HBS1_N PF08938.10 EGF83013.1 - 4.7 7.6 11.0 17 5.8 11.0 1.8 1 1 0 1 1 1 0 HBS1 N-terminus GTP_EFTU PF00009.27 EGF83014.1 - 3.3e-44 150.8 0.0 4.1e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGF83014.1 - 2e-18 66.7 0.1 3.4e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGF83014.1 - 6.7e-09 36.0 0.3 1.8e-08 34.7 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF83014.1 - 6.5e-06 26.2 0.0 4.7e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGF83014.1 - 0.0055 16.2 0.0 0.066 12.7 0.0 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.6 EGF83014.1 - 0.013 15.4 0.9 0.045 13.7 0.8 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Gtr1_RagA PF04670.12 EGF83014.1 - 0.026 13.9 0.8 0.4 10.0 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGF83014.1 - 0.075 12.6 0.1 6.3 6.3 0.1 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 EGF83014.1 - 0.089 12.2 0.1 2 7.8 0.0 2.4 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_transf_92 PF01697.27 EGF83015.1 - 1e-20 74.5 1.2 1e-20 74.5 1.2 2.3 2 1 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EGF83015.1 - 4.3e-12 46.4 0.1 2.6e-11 43.9 0.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 YL1 PF05764.13 EGF83015.1 - 2.6 8.1 4.7 4 7.5 4.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L14 PF00238.19 EGF83016.1 - 4.8e-46 155.8 4.7 5.3e-46 155.7 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PapD-like PF14874.6 EGF83017.1 - 6.2e-07 29.5 0.0 1.3e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Flagellar-associated PapD-like DUF1573 PF07610.11 EGF83017.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) PI3_PI4_kinase PF00454.27 EGF83019.1 - 7.5e-58 196.3 0.1 3.3e-57 194.2 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGF83019.1 - 1.6e-07 31.0 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 FATC domain HALZ PF02183.18 EGF83020.1 - 0.0014 18.8 1.0 0.0014 18.8 1.0 4.7 4 1 1 5 5 5 2 Homeobox associated leucine zipper Put_Phosphatase PF06888.12 EGF83021.1 - 9.5e-57 192.1 0.1 1.1e-56 191.9 0.1 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EGF83021.1 - 1.2e-06 29.1 0.1 5.2e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EGF83021.1 - 0.43 10.3 2.9 13 5.5 2.9 2.5 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Ribosomal_S8e PF01201.22 EGF83022.1 - 7.1e-51 172.0 8.7 7.1e-51 172.0 8.7 1.8 1 1 1 2 2 2 1 Ribosomal protein S8e XRN_M PF17846.1 EGF83022.1 - 0.12 11.3 2.8 0.17 10.8 2.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain LMBR1 PF04791.16 EGF83022.1 - 5.2 5.8 5.1 6.4 5.6 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GTP_EFTU PF00009.27 EGF83023.1 - 5.4e-66 221.8 0.2 9.5e-66 221.0 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGF83023.1 - 1.9e-31 108.4 0.0 5.7e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGF83023.1 - 9.4e-22 76.9 0.0 2.9e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGF83023.1 - 3.6e-13 49.4 0.1 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGF83023.1 - 6.6e-11 42.4 0.1 1.7e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF83023.1 - 0.00044 20.3 0.1 0.0011 19.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S5_C PF03719.15 EGF83024.1 - 1.2e-23 82.3 0.0 2.3e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EGF83024.1 - 2.5e-19 69.0 1.6 4e-19 68.4 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DEAD PF00270.29 EGF83025.1 - 3.2e-49 167.0 0.0 1.5e-48 164.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF83025.1 - 2.2e-32 111.7 0.0 6.8e-32 110.1 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF83025.1 - 9.4e-05 22.5 0.0 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGF83025.1 - 0.38 11.0 1.0 7 6.9 0.4 2.9 1 1 1 2 2 2 0 AAA domain GRP PF07172.11 EGF83025.1 - 1.6 9.5 26.5 7.7 7.3 27.0 1.9 2 0 0 2 2 2 0 Glycine rich protein family SecY PF00344.20 EGF83026.1 - 7.5e-74 248.7 11.6 1.1e-73 248.2 11.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGF83026.1 - 1.4e-18 66.5 0.3 3.6e-18 65.1 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p NIF PF03031.18 EGF83028.1 - 1e-56 191.0 0.3 1.3e-56 190.7 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGF83028.1 - 0.0046 17.4 0.2 0.051 14.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase AMP-binding PF00501.28 EGF83029.1 - 2e-66 224.4 0.0 2.5e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF83029.1 - 2.6e-24 86.0 0.0 4.8e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGF83029.1 - 7.9e-17 60.9 0.3 1.8e-16 59.8 0.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_C14 PF00656.22 EGF83031.1 - 1.8e-52 178.8 0.0 3e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 EGF83032.1 - 1.1e-50 173.0 0.0 1.6e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Actino_peptide PF14408.6 EGF83032.1 - 0.33 11.1 8.1 5.1 7.3 6.0 2.5 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes Med8 PF10232.9 EGF83033.1 - 6.6e-07 29.2 0.2 1.2e-06 28.3 0.2 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 U3_assoc_6 PF08640.11 EGF83033.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Abhydro_lipase PF04083.16 EGF83034.1 - 2.7e-16 58.9 0.1 6.7e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGF83034.1 - 7.8e-14 51.9 0.2 7.1e-13 48.8 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGF83034.1 - 2.4e-08 33.5 0.0 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF83034.1 - 9.3e-06 26.4 0.0 1.2e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 EGF83034.1 - 2e-05 23.9 0.2 6e-05 22.4 0.2 1.6 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase ATG22 PF11700.8 EGF83035.1 - 6.2e-120 401.0 23.2 1.7e-110 369.9 18.3 2.0 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGF83035.1 - 9.6e-06 24.7 33.5 0.0025 16.8 0.1 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily F-box-like PF12937.7 EGF83036.1 - 1.5e-06 28.0 1.8 1.5e-06 28.0 1.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGF83036.1 - 2.2e-05 24.2 1.3 5.8e-05 22.9 1.3 1.7 1 0 0 1 1 1 1 F-box domain Chitin_bind_1 PF00187.19 EGF83037.1 - 1.3e-28 99.1 71.0 2e-10 41.0 18.9 3.3 3 0 0 3 3 3 3 Chitin recognition protein BNR PF02012.20 EGF83037.1 - 0.45 10.7 2.9 1.6e+02 3.0 0.1 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat SAGA-Tad1 PF12767.7 EGF83038.1 - 5.3e-32 111.4 0.0 1.7e-31 109.8 0.0 1.7 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit AAA PF00004.29 EGF83039.1 - 8.5e-43 145.9 0.0 1.6e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF83039.1 - 1e-11 44.4 0.2 2.1e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGF83039.1 - 1.5e-09 37.7 0.8 2.3e-09 37.1 0.1 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGF83039.1 - 1.6e-07 31.4 0.1 5.9e-06 26.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF83039.1 - 8.2e-07 29.6 0.1 0.00044 20.7 0.1 2.9 3 1 0 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 EGF83039.1 - 3e-06 27.5 0.0 1e-05 25.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGF83039.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF83039.1 - 0.00021 21.6 0.1 0.0081 16.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EGF83039.1 - 0.0008 20.0 0.0 0.0042 17.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 EGF83039.1 - 0.0018 17.5 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGF83039.1 - 0.0021 17.6 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGF83039.1 - 0.0027 17.5 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGF83039.1 - 0.0033 16.8 0.0 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGF83039.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGF83039.1 - 0.0043 17.0 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGF83039.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EGF83039.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EGF83039.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EGF83039.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGF83039.1 - 0.014 15.1 0.0 0.068 12.9 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGF83039.1 - 0.018 15.1 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF83039.1 - 0.029 14.6 0.0 0.086 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EGF83039.1 - 0.039 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EGF83039.1 - 0.043 13.2 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 EGF83039.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGF83039.1 - 0.091 12.7 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 EGF83039.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EGF83039.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 EGF83039.1 - 0.12 12.0 0.1 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_19 PF13245.6 EGF83039.1 - 0.14 12.5 0.2 0.34 11.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Chitin_bind_1 PF00187.19 EGF83040.1 - 1.8e-56 188.3 209.0 2e-08 34.5 15.1 9.5 9 0 0 9 9 9 9 Chitin recognition protein Ldh_2 PF02615.14 EGF83040.1 - 0.29 10.3 0.0 13 4.8 0.0 2.1 2 0 0 2 2 2 0 Malate/L-lactate dehydrogenase ubiquitin PF00240.23 EGF83041.1 - 0.018 14.8 2.1 0.12 12.2 2.1 2.0 1 1 0 1 1 1 0 Ubiquitin family Na_H_Exchanger PF00999.21 EGF83042.1 - 4.6e-40 137.6 37.6 6.4e-40 137.1 37.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorA PF01544.18 EGF83042.1 - 2.2 7.5 7.2 4.1 6.6 7.2 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Chitin_bind_1 PF00187.19 EGF83043.1 - 1.2e-59 198.4 208.7 5.9e-09 36.2 16.6 9.4 9 0 0 9 9 9 9 Chitin recognition protein SAGA-Tad1 PF12767.7 EGF83044.1 - 5.6e-32 111.4 0.0 2.8e-31 109.1 0.0 1.9 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit zf-AN1 PF01428.16 EGF83045.1 - 4.4e-13 49.1 3.2 4.4e-13 49.1 3.2 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGF83045.1 - 0.00033 21.0 1.7 0.00056 20.2 1.7 1.4 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain Peptidase_M16_C PF05193.21 EGF83047.1 - 1.5e-13 51.1 0.0 1.4e-08 35.0 0.0 3.0 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGF83047.1 - 4.8e-11 42.9 0.1 4.2e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) CENP-B_dimeris PF09026.10 EGF83047.1 - 0.072 13.5 12.8 0.17 12.3 12.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 EGF83047.1 - 0.54 9.5 5.8 0.88 8.8 5.8 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EGF83047.1 - 0.65 8.0 16.2 1.1 7.2 16.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EGF83047.1 - 1.7 8.3 5.3 3.4 7.3 5.3 1.4 1 0 0 1 1 1 0 FAM176 family TraH_2 PF06871.11 EGF83047.1 - 2.3 7.8 4.7 4.8 6.8 4.7 1.5 1 0 0 1 1 1 0 TraH_2 Sigma70_ner PF04546.13 EGF83047.1 - 2.4 8.0 8.1 4.3 7.2 8.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EGF83047.1 - 6 6.2 12.8 10 5.4 12.8 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 EGF83047.1 - 6.9 6.2 12.4 13 5.3 12.4 1.3 1 0 0 1 1 1 0 PPP4R2 zf-HIT PF04438.16 EGF83049.1 - 1.9e-09 37.2 12.0 1.9e-09 37.2 12.0 2.8 3 0 0 3 3 3 1 HIT zinc finger CDC37_C PF08564.10 EGF83049.1 - 0.0041 17.2 0.6 0.46 10.6 0.0 2.4 2 0 0 2 2 2 2 Cdc37 C terminal domain YL1_C PF08265.11 EGF83049.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Ribosomal_S8 PF00410.19 EGF83050.1 - 3.2e-20 72.4 0.0 2.5e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 TPR_2 PF07719.17 EGF83052.1 - 4.7e-38 126.2 36.7 0.0014 18.6 0.1 17.7 21 0 0 21 21 16 9 Tetratricopeptide repeat TPR_19 PF14559.6 EGF83052.1 - 1.3e-37 128.2 26.3 2.8e-05 24.6 0.2 14.1 12 4 3 15 15 14 8 Tetratricopeptide repeat TPR_14 PF13428.6 EGF83052.1 - 3.1e-33 111.6 4.7 0.24 12.3 0.0 16.2 12 4 5 17 17 16 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGF83052.1 - 4e-28 96.0 42.6 0.00088 19.0 0.2 17.5 19 0 0 19 19 19 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGF83052.1 - 5.6e-28 94.8 42.4 0.00054 20.0 0.0 16.2 18 0 0 18 18 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGF83052.1 - 2.1e-26 92.3 0.0 1.3e-05 25.8 0.0 13.0 11 3 1 14 14 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGF83052.1 - 2.8e-17 62.1 15.6 0.018 14.7 0.0 11.4 11 1 1 12 12 11 5 TPR repeat TPR_7 PF13176.6 EGF83052.1 - 3.9e-17 60.9 10.7 0.028 14.4 0.0 12.1 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF83052.1 - 2.9e-14 52.3 16.9 1.8 9.1 0.1 14.1 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGF83052.1 - 2.7e-13 49.6 27.9 0.44 11.3 0.0 14.5 17 0 0 17 17 14 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGF83052.1 - 6.2e-13 48.8 34.6 0.0073 16.6 0.1 12.3 11 5 1 12 12 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF83052.1 - 8.8e-13 48.3 41.9 0.0017 18.5 1.3 11.2 8 4 6 14 14 13 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGF83052.1 - 3.1e-08 33.6 5.1 2 8.6 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGF83052.1 - 3e-06 27.1 12.1 0.72 9.5 0.1 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat-like domain SNAP PF14938.6 EGF83052.1 - 9e-06 25.3 22.4 0.02 14.3 3.0 6.5 5 1 1 6 6 6 3 Soluble NSF attachment protein, SNAP HrpB1_HrpK PF09613.10 EGF83052.1 - 0.00088 18.9 1.9 0.24 11.0 0.0 5.1 6 1 1 7 7 7 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 EGF83052.1 - 0.0016 18.7 15.2 1.2 9.6 0.8 7.7 6 3 2 9 9 7 1 Tetratricopeptide repeat SPOB_a PF14689.6 EGF83052.1 - 0.0022 17.7 3.6 7.9 6.3 0.0 6.4 7 0 0 7 7 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain SRP_TPR_like PF17004.5 EGF83052.1 - 0.0052 16.8 13.4 12 5.9 0.0 7.2 5 3 2 7 7 7 0 Putative TPR-like repeat TPR_4 PF07721.14 EGF83052.1 - 0.0057 17.2 0.8 28 5.7 0.1 5.0 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF83052.1 - 0.026 13.9 16.5 7.5 5.8 0.1 7.0 7 1 1 8 8 8 0 MalT-like TPR region Fis1_TPR_C PF14853.6 EGF83052.1 - 0.03 14.4 3.2 15 5.8 0.0 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EGF83052.1 - 0.27 11.6 2.1 28 5.1 0.0 3.9 4 0 0 4 4 3 0 Bacterial transcriptional activator domain YfiO PF13525.6 EGF83052.1 - 0.42 10.3 14.5 2.4 7.8 0.0 6.7 7 2 1 8 8 8 0 Outer membrane lipoprotein ChAPs PF09295.10 EGF83052.1 - 0.48 9.4 10.1 0.11 11.5 0.2 4.0 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) YfdX PF10938.8 EGF83052.1 - 0.71 9.8 8.2 38 4.2 0.2 4.6 4 1 1 5 5 4 0 YfdX protein ANAPC5 PF12862.7 EGF83052.1 - 8.3 6.6 7.1 9 6.4 0.0 4.7 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 N2227 PF07942.12 EGF83053.1 - 1.4e-23 83.4 1.3 9.4e-12 44.7 0.1 2.8 2 1 1 3 3 3 2 N2227-like protein THOC2_N PF16134.5 EGF83055.1 - 1.1e-174 582.6 0.1 1.9e-174 581.8 0.0 1.4 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EGF83055.1 - 9.2e-45 153.1 2.4 1.8e-44 152.2 2.4 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGF83055.1 - 4.1e-31 106.9 0.0 1.3e-30 105.3 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Methyltransf_4 PF02390.17 EGF83056.1 - 6.1e-48 162.5 0.0 9.2e-48 162.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGF83056.1 - 0.042 13.4 0.1 1.2 8.6 0.1 2.1 1 1 0 2 2 2 0 Methyltransferase small domain DUF1980 PF09323.10 EGF83057.1 - 0.08 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) m04gp34like PF12216.8 EGF83058.1 - 0.16 11.5 1.3 0.41 10.2 0.1 2.1 2 0 0 2 2 2 0 Immune evasion protein Desmo_N PF06771.11 EGF83059.1 - 0.091 13.1 0.2 0.18 12.2 0.2 1.5 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus DUF2663 PF10864.8 EGF83059.1 - 2.7 8.4 17.6 0.17 12.3 0.4 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2663) YIF1 PF03878.15 EGF83060.1 - 4.2e-79 265.4 2.7 7.6e-79 264.6 2.7 1.4 1 0 0 1 1 1 1 YIF1 Homoserine_dh PF00742.19 EGF83060.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase PIG-H PF10181.9 EGF83061.1 - 7.2e-21 73.8 1.2 1.1e-20 73.2 0.3 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component DUF3717 PF12512.8 EGF83061.1 - 0.14 12.0 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Alg6_Alg8 PF03155.15 EGF83062.1 - 2.7e-135 452.1 28.1 3.4e-135 451.7 28.1 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2644 PF10841.8 EGF83062.1 - 0.098 12.9 5.7 0.59 10.4 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) AAA PF00004.29 EGF83063.1 - 1.3e-41 142.1 0.0 2.3e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGF83063.1 - 4.6e-07 29.7 0.0 1.2e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF83063.1 - 1.4e-06 28.6 1.8 0.00089 19.5 0.1 3.1 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 EGF83063.1 - 2.4e-06 27.6 0.2 2.3e-05 24.4 0.2 2.6 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGF83063.1 - 2.6e-06 27.7 0.0 5.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGF83063.1 - 1.4e-05 25.6 1.1 7.5e-05 23.2 0.8 2.4 1 1 1 2 2 2 1 AAA ATPase domain Vps4_C PF09336.10 EGF83063.1 - 1.5e-05 24.9 0.1 0.00071 19.5 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 EGF83063.1 - 1.9e-05 24.1 0.1 5.9e-05 22.4 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EGF83063.1 - 2.5e-05 24.4 0.0 8.1e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_lid_3 PF17862.1 EGF83063.1 - 2.8e-05 23.8 0.2 0.00011 21.9 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain TniB PF05621.11 EGF83063.1 - 3.1e-05 23.5 0.2 0.34 10.3 0.0 2.8 2 1 1 3 3 3 2 Bacterial TniB protein AAA_14 PF13173.6 EGF83063.1 - 3.7e-05 23.8 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGF83063.1 - 0.00019 20.7 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGF83063.1 - 0.00024 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGF83063.1 - 0.00026 21.5 0.1 0.0006 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGF83063.1 - 0.00053 19.8 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGF83063.1 - 0.00058 19.5 0.0 0.018 14.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGF83063.1 - 0.00061 19.2 0.1 0.0013 18.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGF83063.1 - 0.0014 18.0 0.5 0.48 9.7 0.1 2.3 1 1 1 2 2 2 2 KaiC Guanylate_kin PF00625.21 EGF83063.1 - 0.0018 18.0 0.2 0.015 15.0 0.0 2.3 1 1 0 2 2 2 1 Guanylate kinase AAA_7 PF12775.7 EGF83063.1 - 0.0019 17.8 0.3 0.0088 15.6 0.1 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGF83063.1 - 0.0019 18.5 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EGF83063.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 EGF83063.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.6 1 1 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EGF83063.1 - 0.0058 17.2 0.0 0.0095 16.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 EGF83063.1 - 0.006 16.5 0.3 0.048 13.6 0.3 2.2 1 1 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.26 EGF83063.1 - 0.0068 16.1 0.1 0.03 14.0 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.6 EGF83063.1 - 0.011 16.1 0.1 0.032 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 EGF83063.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein SRPRB PF09439.10 EGF83063.1 - 0.024 14.1 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 EGF83063.1 - 0.025 14.6 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EGF83063.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EGF83063.1 - 0.03 14.8 0.2 0.099 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGF83063.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 EGF83063.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 EGF83063.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGF83063.1 - 0.08 12.7 0.2 0.17 11.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGF83063.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EGF83063.1 - 0.11 11.7 0.4 1.7 7.8 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain CPT PF07931.12 EGF83063.1 - 0.13 12.1 0.2 0.25 11.2 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein FCH PF00611.23 EGF83063.1 - 0.15 12.4 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Hamartin PF04388.12 EGF83064.1 - 0.26 9.9 4.3 0.34 9.5 4.3 1.1 1 0 0 1 1 1 0 Hamartin protein Polysacc_synt_4 PF04669.13 EGF83065.1 - 3.2e-20 72.5 0.1 2.8e-12 46.6 0.1 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis Pkinase PF00069.25 EGF83066.1 - 8.6e-54 182.6 0.0 3.5e-39 134.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83066.1 - 2e-23 83.0 0.0 8.9e-23 80.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF83066.1 - 5.3e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF83066.1 - 0.00051 19.5 0.0 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGF83066.1 - 0.0077 15.2 1.8 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGF83066.1 - 0.009 14.8 0.3 0.031 13.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGF83066.1 - 0.053 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGF83066.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.14 EGF83067.1 - 0.0022 18.0 0.8 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Peptidase_C50 PF03568.17 EGF83068.1 - 3.8e-100 335.8 0.6 4.7e-62 210.4 0.1 2.7 1 1 1 2 2 2 2 Peptidase family C50 CHAT PF12770.7 EGF83068.1 - 0.063 12.7 0.5 1.8 7.9 0.0 2.8 2 1 0 3 3 3 0 CHAT domain DUF5572 PF17733.1 EGF83070.1 - 3.4e-12 46.0 0.3 5.6e-12 45.3 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) RasGAP PF00616.19 EGF83071.1 - 1.8e-59 201.0 0.0 3.4e-59 200.0 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGF83071.1 - 6.9e-30 104.0 2.4 1.7e-29 102.7 2.4 1.7 1 0 0 1 1 1 1 RasGAP C-terminus DUF4047 PF13256.6 EGF83071.1 - 0.13 12.4 0.2 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Herpes_UL14 PF03580.14 EGF83071.1 - 0.26 11.5 3.8 0.21 11.9 1.7 1.8 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Prefoldin_2 PF01920.20 EGF83071.1 - 0.37 10.8 4.6 0.12 12.4 0.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 EGF83071.1 - 2.8 8.6 7.2 15 6.3 1.3 2.8 2 0 0 2 2 2 0 Initiation control protein YabA G-alpha PF00503.20 EGF83072.1 - 4.4e-91 305.7 7.3 5.3e-91 305.4 7.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF83072.1 - 2.5e-13 49.9 1.3 1.4e-10 40.9 0.1 2.8 3 1 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 EGF83072.1 - 0.00013 22.2 0.2 0.29 11.3 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGF83072.1 - 0.00035 20.2 0.1 0.12 11.9 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 EGF83072.1 - 0.0044 16.6 1.3 0.18 11.4 0.1 2.5 2 1 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 EGF83072.1 - 0.073 12.4 1.9 1.4 8.3 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EGF83072.1 - 0.077 12.7 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF83072.1 - 0.12 12.5 0.2 25 5.0 0.0 2.8 2 1 1 3 3 3 0 50S ribosome-binding GTPase G-alpha PF00503.20 EGF83073.1 - 5.3e-90 302.1 8.5 6.6e-90 301.8 8.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF83073.1 - 4.9e-18 65.2 0.4 6.6e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGF83073.1 - 2.1e-05 24.7 0.5 0.088 13.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGF83073.1 - 0.0028 17.3 1.6 0.077 12.6 0.1 2.4 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 EGF83073.1 - 0.012 15.2 0.5 3.6 7.1 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGF83073.1 - 0.034 13.5 9.3 0.017 14.5 0.7 2.4 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGF83074.1 - 8.4e-89 298.2 5.2 1e-88 297.9 5.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF83074.1 - 1.9e-15 56.7 0.2 4.7e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 EGF83074.1 - 0.00094 18.7 0.2 2.4 7.5 0.0 3.1 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit Roc PF08477.13 EGF83074.1 - 0.0016 18.7 0.3 2.2 8.5 0.0 3.1 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGF83074.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_15 PF13175.6 EGF83074.1 - 0.031 14.0 1.1 0.042 13.5 1.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 EGF83074.1 - 0.046 13.3 0.4 0.6 9.6 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF83074.1 - 0.06 13.4 0.1 9.4 6.4 0.1 3.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGF83074.1 - 0.075 13.5 0.1 0.2 12.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF3140 PF11338.8 EGF83074.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) TLD PF07534.16 EGF83076.1 - 5.6e-29 101.2 0.4 9.7e-29 100.4 0.4 1.4 1 0 0 1 1 1 1 TLD MMM1 PF10296.9 EGF83077.1 - 4e-12 45.9 0.5 4.1e-05 22.8 0.0 3.1 2 1 1 3 3 3 3 Maintenance of mitochondrial morphology protein 1 Peptidase_S24 PF00717.23 EGF83078.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGF83078.1 - 3e-07 30.3 0.0 0.0015 18.3 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 CAP_N PF01213.19 EGF83079.1 - 0.00026 20.6 0.6 0.00046 19.8 0.6 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EGF83079.1 - 2.2 8.4 6.0 0.44 10.6 2.3 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Spt5-NGN PF03439.13 EGF83080.1 - 3.3e-24 84.6 0.1 7.2e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EGF83080.1 - 2.7e-17 63.5 14.1 2.7e-17 63.5 14.1 3.1 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EGF83080.1 - 6.1e-14 51.4 30.5 1.3e-05 24.9 3.8 7.8 9 0 0 9 9 9 4 KOW motif CTD PF12815.7 EGF83080.1 - 9.5e-11 42.1 27.7 9.2e-10 38.9 23.9 3.3 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KN17_SH3 PF18131.1 EGF83080.1 - 0.0004 20.4 0.1 0.006 16.7 0.0 3.0 3 0 0 3 3 3 1 KN17 SH3-like C-terminal domain DUF3912 PF13051.6 EGF83080.1 - 0.0063 16.8 0.7 0.039 14.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) Nop14 PF04147.12 EGF83080.1 - 0.094 10.9 21.4 0.13 10.4 21.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGF83080.1 - 5.6 6.2 30.6 10 5.3 30.6 1.3 1 0 0 1 1 1 0 BUD22 Pex2_Pex12 PF04757.14 EGF83081.1 - 3.3e-39 134.8 2.5 4.1e-39 134.5 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGF83081.1 - 0.00016 21.4 0.9 0.00028 20.7 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF83081.1 - 0.00088 19.1 1.4 0.0018 18.1 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF83081.1 - 0.038 13.8 1.3 0.1 12.5 1.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HTH_9 PF08221.11 EGF83081.1 - 0.085 13.0 0.4 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain zf-RING_2 PF13639.6 EGF83081.1 - 0.25 11.7 1.6 0.52 10.7 1.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EGF83081.1 - 0.61 10.3 5.0 1.2 9.4 5.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING WD40 PF00400.32 EGF83082.1 - 1.3e-13 51.2 17.3 0.00028 21.6 1.4 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83082.1 - 7.1e-08 32.6 0.3 0.12 12.6 0.1 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Tox-SGS PF15651.6 EGF83082.1 - 0.037 14.3 0.2 0.077 13.2 0.2 1.5 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin DPPIV_N PF00930.21 EGF83082.1 - 0.079 11.7 2.8 3.2 6.4 1.2 2.6 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 EGF83082.1 - 0.64 9.7 4.1 8 6.1 0.1 3.1 2 1 2 4 4 4 0 Lipoprotein LpqB beta-propeller domain Pex14_N PF04695.13 EGF83083.1 - 2.5e-29 103.0 0.0 5.9e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CENP-F_leu_zip PF10473.9 EGF83083.1 - 0.0011 19.0 5.0 0.0066 16.5 5.7 1.9 2 1 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 EGF83083.1 - 0.0041 16.5 2.2 0.0055 16.1 2.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Activator_LAG-3 PF11498.8 EGF83083.1 - 0.0077 15.2 3.4 0.0077 15.2 3.4 1.4 2 0 0 2 2 2 1 Transcriptional activator LAG-3 BLOC1_2 PF10046.9 EGF83083.1 - 0.015 15.6 4.6 0.035 14.4 4.6 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LXG PF04740.12 EGF83083.1 - 0.046 13.4 6.9 0.11 12.1 6.9 1.7 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF1664 PF07889.12 EGF83083.1 - 0.059 13.4 3.9 0.083 12.9 3.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGF83083.1 - 0.099 12.7 5.6 0.27 11.3 4.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 EGF83083.1 - 0.1 12.7 7.3 0.055 13.6 5.1 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ARS2 PF04959.13 EGF83083.1 - 0.11 12.8 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Arsenite-resistance protein 2 TMPIT PF07851.13 EGF83083.1 - 0.37 10.0 3.4 0.7 9.1 3.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein Rsd_AlgQ PF04353.13 EGF83083.1 - 0.65 9.9 5.2 0.15 12.0 1.5 1.8 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ ATG16 PF08614.11 EGF83083.1 - 1.3 9.2 10.6 0.18 12.0 3.9 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) LRR_8 PF13855.6 EGF83084.1 - 9.3e-27 92.6 32.8 4e-11 42.5 5.2 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGF83084.1 - 1.6e-20 72.8 28.4 6.3e-08 32.8 1.7 4.6 3 2 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGF83084.1 - 2e-10 40.5 9.6 5.7e-06 25.9 2.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EGF83084.1 - 1.2e-06 28.2 25.0 0.53 11.0 0.6 7.4 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 EGF83084.1 - 1.7e-05 24.5 20.9 0.048 13.7 0.5 6.3 6 0 0 6 6 6 4 Leucine Rich repeat SieB PF14163.6 EGF83084.1 - 0.05 13.1 0.1 9.3 5.7 0.0 2.6 1 1 0 2 2 2 0 Super-infection exclusion protein B LRR_5 PF13306.6 EGF83084.1 - 0.064 13.2 0.8 0.091 12.7 0.8 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) RhoGAP PF00620.27 EGF83085.1 - 1.4e-29 102.9 0.1 2.5e-20 72.8 0.0 2.5 1 1 1 2 2 2 2 RhoGAP domain RNase_PH PF01138.21 EGF83086.1 - 3.3e-35 121.5 0.0 5e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGF83086.1 - 0.00018 21.5 0.3 0.0003 20.8 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 QWRF PF04484.12 EGF83087.1 - 0.26 11.0 18.5 0.74 9.5 18.5 1.7 1 1 0 1 1 1 0 QWRF family SPX PF03105.19 EGF83087.1 - 1.8 8.4 10.8 2.6 7.9 10.8 1.3 1 0 0 1 1 1 0 SPX domain MOZ_SAS PF01853.18 EGF83088.1 - 3.8e-84 280.8 0.6 6.1e-84 280.1 0.6 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGF83088.1 - 9.4e-20 70.0 3.1 1.7e-19 69.2 0.4 2.6 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGF83088.1 - 0.0021 18.4 0.2 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGF83088.1 - 0.03 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_16 PF05301.11 EGF83088.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 COG4 PF08318.12 EGF83089.1 - 1.6e-85 287.2 0.1 2.9e-85 286.3 0.1 1.4 1 0 0 1 1 1 1 COG4 transport protein COQ9 PF08511.11 EGF83089.1 - 0.068 12.9 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 COQ9 Nsp1_C PF05064.13 EGF83089.1 - 0.38 10.6 3.5 0.43 10.4 0.8 2.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region SHE3 PF17078.5 EGF83089.1 - 4.5 6.9 9.2 0.13 12.0 0.6 2.6 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 Ras PF00071.22 EGF83090.1 - 1.4e-53 180.9 0.1 1.6e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF83090.1 - 4e-19 69.0 0.0 6.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF83090.1 - 6.3e-11 42.0 0.0 7.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGF83090.1 - 1.3e-07 31.6 0.0 0.00032 20.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGF83090.1 - 0.00027 20.5 0.0 0.00075 19.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGF83090.1 - 0.0034 17.2 0.5 0.006 16.4 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGF83090.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 EGF83090.1 - 0.04 13.2 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Septin MMR_HSR1_Xtn PF16897.5 EGF83090.1 - 0.071 13.1 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain CH PF00307.31 EGF83091.1 - 1.3e-14 54.2 0.0 6.3e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain Tropomyosin_1 PF12718.7 EGF83091.1 - 3.9e-05 23.8 10.1 3.9e-05 23.8 10.1 2.1 2 0 0 2 2 2 1 Tropomyosin like CDC24 PF06395.11 EGF83091.1 - 0.003 17.8 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin DUF3450 PF11932.8 EGF83091.1 - 0.012 14.9 7.1 0.012 14.9 7.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Filament PF00038.21 EGF83091.1 - 0.018 14.6 9.1 0.018 14.6 9.1 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF641 PF04859.12 EGF83091.1 - 0.019 15.3 1.3 0.019 15.3 1.3 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FliJ PF02050.16 EGF83091.1 - 0.028 14.6 10.3 0.034 14.4 7.5 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein V_ATPase_I PF01496.19 EGF83091.1 - 0.52 8.2 4.6 0.74 7.7 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 EGF83091.1 - 0.63 10.1 19.9 0.14 12.2 12.9 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 EGF83091.1 - 0.89 9.9 14.0 0.054 13.8 8.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PKcGMP_CC PF16808.5 EGF83091.1 - 2 8.4 7.2 0.13 12.2 1.6 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Jnk-SapK_ap_N PF09744.9 EGF83091.1 - 3 8.0 16.1 0.65 10.2 8.5 2.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EGF83091.1 - 3.5 6.4 15.4 0.027 13.4 7.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 EGF83091.1 - 4 6.7 15.5 0.17 11.2 6.6 2.2 2 0 0 2 2 2 0 FAM76 protein Fez1 PF06818.15 EGF83091.1 - 4 7.8 18.2 11 6.4 18.2 1.7 1 1 0 1 1 1 0 Fez1 Phage_GP20 PF06810.11 EGF83091.1 - 4.7 7.0 11.3 0.22 11.3 4.5 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF3552 PF12072.8 EGF83091.1 - 5.1 6.5 16.0 0.18 11.2 9.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 EGF83091.1 - 6.3 7.2 15.4 0.83 10.1 9.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 EGF83091.1 - 6.8 6.9 18.1 0.21 11.8 10.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding EF-hand_13 PF17958.1 EGF83092.1 - 1.6e-13 50.3 0.1 4.9e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EGF83092.1 - 2.9e-12 46.8 0.1 1.1e-11 45.1 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGF83092.1 - 1.7e-05 24.1 0.0 5.4e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EGF83092.1 - 0.0004 20.2 0.3 0.0004 20.2 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGF83092.1 - 0.0066 16.3 0.0 0.2 11.7 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EGF83092.1 - 0.032 13.8 3.5 0.04 13.5 0.0 3.0 4 0 0 4 4 4 0 EF hand CDC50 PF03381.15 EGF83093.1 - 0.18 11.3 0.7 0.28 10.7 0.7 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Sacchrp_dh_C PF16653.5 EGF83094.1 - 8.4e-94 314.6 0.0 1.4e-93 313.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGF83094.1 - 2.6e-25 89.2 0.0 4.1e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGF83094.1 - 1.6e-06 28.1 0.1 2.6e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EGF83094.1 - 2.9e-06 27.4 0.0 9e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGF83094.1 - 0.00014 22.4 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EGF83094.1 - 0.0015 19.4 0.0 0.0027 18.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGF83094.1 - 0.0042 17.7 0.1 0.0072 17.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGF83094.1 - 0.0095 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NmrA PF05368.13 EGF83094.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family S1-like PF14444.6 EGF83095.1 - 2.8 8.0 7.9 32 4.5 0.1 4.2 4 0 0 4 4 4 0 S1-like SE PF08491.10 EGF83096.1 - 3.1e-104 347.9 0.0 3.8e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGF83096.1 - 3.1e-15 56.3 0.0 8.8e-15 54.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGF83096.1 - 1.7e-08 34.5 0.3 1.6e-05 24.7 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGF83096.1 - 1.4e-07 31.0 0.4 0.00013 21.2 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EGF83096.1 - 3.1e-07 29.8 0.2 1.4e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGF83096.1 - 3.3e-06 27.2 1.5 4.4e-06 26.8 0.4 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGF83096.1 - 8.9e-05 21.9 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF83096.1 - 0.00013 21.5 0.5 0.00018 21.0 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGF83096.1 - 0.00033 20.0 0.4 0.0015 17.8 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EGF83096.1 - 0.00072 18.4 0.1 0.001 17.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 EGF83096.1 - 0.0026 16.7 0.1 0.047 12.5 0.1 2.3 3 0 0 3 3 3 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EGF83096.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDI PF00996.18 EGF83096.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Ribosomal_60s PF00428.19 EGF83097.1 - 1.2e-24 86.7 9.8 1.4e-24 86.4 9.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PfkB PF00294.24 EGF83099.1 - 2.7e-64 217.3 0.1 3.2e-64 217.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MBR1 PF17058.5 EGF83100.1 - 0.1 12.9 1.1 0.14 12.4 1.1 1.2 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 KI67R PF08065.12 EGF83100.1 - 0.42 11.2 8.0 0.65 10.6 8.0 1.2 1 0 0 1 1 1 0 KI67R (NUC007) repeat PI-PLC-X PF00388.19 EGF83101.1 - 2e-50 170.2 0.0 4.2e-50 169.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGF83101.1 - 2.1e-40 137.7 0.2 6e-40 136.2 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGF83101.1 - 1.3e-06 28.7 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 EGF83101.1 - 0.0071 16.9 0.6 0.028 15.0 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_14 PF17787.1 EGF83101.1 - 0.01 15.7 0.0 0.066 13.1 0.0 2.1 1 1 0 1 1 1 0 PH domain DUF4580 PF15162.6 EGF83101.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) EF-hand_7 PF13499.6 EGF83101.1 - 0.049 14.1 0.1 0.31 11.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Acetyltransf_2 PF00797.17 EGF83102.1 - 5.6e-21 75.4 0.0 9e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 N-acetyltransferase Pkinase PF00069.25 EGF83103.1 - 2.6e-59 200.8 0.0 5.1e-58 196.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83103.1 - 2.5e-22 79.4 0.1 2.4e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF83103.1 - 0.00038 19.9 0.5 0.029 13.7 0.0 2.9 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 EGF83103.1 - 0.0021 17.7 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGF83103.1 - 0.11 12.3 0.2 0.39 10.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 EGF83103.1 - 0.12 13.1 0.4 0.39 11.4 0.4 1.9 1 1 0 1 1 1 0 Protein kinase C terminal domain Kdo PF06293.14 EGF83103.1 - 0.14 11.5 0.7 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCRF PF03462.18 EGF83104.1 - 6e-47 160.0 1.1 6e-47 160.0 1.1 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGF83104.1 - 3e-36 123.9 1.0 3e-36 123.9 1.0 1.8 2 0 0 2 2 2 1 RF-1 domain Img2 PF05046.14 EGF83104.1 - 0.0059 16.9 0.3 3 8.2 0.0 3.4 2 1 1 3 3 3 1 Mitochondrial large subunit ribosomal protein (Img2) TcpS PF17456.2 EGF83104.1 - 0.27 11.3 3.4 12 5.9 0.0 3.1 3 0 0 3 3 3 0 Toxin-coregulated pilus protein S WD40 PF00400.32 EGF83106.1 - 1.5e-12 47.8 6.3 0.00067 20.4 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EGF83106.1 - 0.0023 16.6 0.3 0.027 13.1 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Rhomboid PF01694.22 EGF83108.1 - 2.2e-06 27.8 14.9 2.2e-06 27.8 14.9 1.9 2 0 0 2 2 2 1 Rhomboid family Laminin_EGF PF00053.24 EGF83108.1 - 0.072 13.2 0.8 0.14 12.3 0.8 1.4 1 1 0 1 1 1 0 Laminin EGF domain NifU_N PF01592.16 EGF83109.1 - 4.1e-52 175.7 0.1 5.5e-52 175.3 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain zf-C2H2 PF00096.26 EGF83110.1 - 3.1e-16 58.8 15.8 8.5e-06 26.0 0.6 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF83110.1 - 2.3e-10 40.4 16.2 0.0011 19.6 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGF83110.1 - 1.1e-05 25.6 2.9 3.5e-05 24.0 2.1 2.4 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EGF83110.1 - 2.4e-05 24.5 17.0 0.023 15.1 0.2 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 EGF83110.1 - 7.2e-05 23.0 10.6 0.18 12.3 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGF83110.1 - 0.0002 21.3 10.4 0.076 13.0 0.3 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF83110.1 - 0.0038 17.5 6.1 0.69 10.3 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding IBR PF01485.21 EGF83110.1 - 0.1 12.8 8.0 0.089 13.0 2.4 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 EGF83110.1 - 0.15 11.9 11.6 2.9 7.7 4.5 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type C1_4 PF07975.12 EGF83110.1 - 1.9 8.8 12.0 9.8 6.5 8.2 3.3 2 1 1 3 3 3 0 TFIIH C1-like domain UPF0020 PF01170.18 EGF83111.1 - 3.9e-10 39.7 0.0 1.8e-08 34.3 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGF83111.1 - 0.0034 17.1 0.0 0.084 12.6 0.0 2.3 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 EGF83111.1 - 0.075 12.3 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase PH PF00169.29 EGF83112.1 - 1.6e-05 25.4 0.6 9.7e-05 22.8 0.2 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EGF83112.1 - 0.0068 16.7 0.1 0.016 15.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RGS PF00615.19 EGF83114.1 - 2.5e-10 40.6 0.2 5e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Imm30 PF15565.6 EGF83114.1 - 0.077 13.1 0.3 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 Immunity protein 30 Importin_rep_4 PF18808.1 EGF83115.1 - 1.3e-25 89.5 0.2 1.3e-25 89.5 0.2 4.3 5 0 0 5 5 4 1 Importin repeat HEAT PF02985.22 EGF83115.1 - 1.4e-21 74.7 16.0 0.00029 20.9 0.0 12.9 13 0 0 13 13 13 5 HEAT repeat HEAT_EZ PF13513.6 EGF83115.1 - 3.7e-21 75.2 12.6 3.9e-08 33.6 0.1 10.1 13 0 0 13 13 12 4 HEAT-like repeat HEAT_2 PF13646.6 EGF83115.1 - 1.8e-15 57.1 4.0 9.9e-05 22.7 0.0 7.5 6 1 2 8 8 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EGF83115.1 - 4.5e-08 33.6 0.2 0.11 13.1 0.0 6.4 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGF83115.1 - 2.8e-07 30.6 2.2 0.0096 15.8 0.0 7.0 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 EGF83115.1 - 3.4e-07 30.2 0.0 0.00087 19.1 0.0 4.4 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Importin_rep_6 PF18829.1 EGF83115.1 - 3.6e-07 30.3 1.4 1.5e-06 28.3 0.1 2.7 3 0 0 3 3 2 1 Importin repeat 6 Cnd1 PF12717.7 EGF83115.1 - 1.7e-06 28.1 1.6 0.044 13.8 0.0 4.6 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGF83115.1 - 0.00082 19.0 2.4 1.6 8.2 0.0 5.4 6 1 1 7 7 7 1 CLASP N terminal MMS19_C PF12460.8 EGF83115.1 - 0.0027 16.9 5.9 1.1 8.2 0.3 4.6 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal ParcG PF10274.9 EGF83115.1 - 0.0044 17.2 0.2 2.2 8.4 0.0 3.5 3 1 0 3 3 3 1 Parkin co-regulated protein DUF4042 PF13251.6 EGF83115.1 - 0.0074 16.0 0.7 8.5 6.0 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) MMS19_N PF14500.6 EGF83115.1 - 0.064 12.8 0.7 1.5 8.4 0.4 3.3 4 1 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 EGF83115.1 - 0.19 11.8 3.9 8.3 6.6 0.0 5.6 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat DNA_topoisoIV PF00521.20 EGF83116.1 - 1.6e-130 435.9 0.0 3.4e-130 434.8 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGF83116.1 - 3.7e-50 169.5 0.2 3.7e-50 169.5 0.2 3.1 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGF83116.1 - 5.5e-25 87.8 0.3 1.7e-24 86.2 0.1 1.9 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 EGF83116.1 - 1.3e-14 54.7 0.3 5.2e-14 52.7 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGF83116.1 - 3.7e-07 30.3 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Pkip-1 PF06878.11 EGF83116.1 - 0.021 15.0 3.7 0.53 10.4 3.7 2.4 1 1 0 1 1 1 0 Pkip-1 protein PRELI PF04707.14 EGF83118.1 - 4.5e-42 143.5 0.0 5.5e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Macro PF01661.21 EGF83119.1 - 1.7e-40 137.8 0.2 2.1e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Macro domain SNF2_N PF00176.23 EGF83120.1 - 1e-43 149.4 1.4 1.9e-43 148.6 1.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EGF83120.1 - 1e-08 34.9 8.0 2.1e-08 33.9 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF83120.1 - 4.8e-08 32.7 9.9 1.1e-07 31.6 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF83120.1 - 6.6e-07 29.6 10.1 2.5e-06 27.7 10.1 2.1 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGF83120.1 - 7.5e-07 28.9 7.4 1.6e-06 27.8 7.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 EGF83120.1 - 7.9e-06 26.2 0.6 3.3e-05 24.2 0.0 2.4 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EGF83120.1 - 3.6e-05 23.5 9.3 8.8e-05 22.3 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF83120.1 - 0.00056 19.8 9.9 0.00056 19.8 9.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF83120.1 - 0.00084 19.3 3.4 0.00084 19.3 3.4 2.3 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGF83120.1 - 0.0049 17.0 7.5 0.014 15.5 7.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2730 PF10805.8 EGF83120.1 - 0.019 15.0 0.1 0.096 12.8 0.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2730) FdhE PF04216.12 EGF83120.1 - 0.048 13.5 1.8 0.13 12.2 1.8 1.7 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-RING_6 PF14835.6 EGF83120.1 - 0.34 10.8 2.0 0.76 9.7 2.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EGF83120.1 - 0.58 10.3 4.9 1.4 9.1 4.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EGF83120.1 - 2 8.7 14.2 8.7 6.7 12.4 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain ID PF18543.1 EGF83121.1 - 0.049 13.7 0.0 5.2e+02 0.8 0.0 5.0 5 0 0 5 5 5 0 Intracellular delivery domain Herpes_pp38 PF04846.13 EGF83121.1 - 1.6 8.7 6.4 3.4e+02 1.2 0.0 5.0 5 0 0 5 5 5 0 Herpesvirus pp38 phosphoprotein Aconitase PF00330.20 EGF83122.1 - 6.6e-106 355.1 0.4 8.3e-105 351.4 0.4 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGF83122.1 - 4.4e-14 52.9 0.0 1.9e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Aconitase C-terminal domain Nipped-B_C PF12830.7 EGF83123.1 - 2e-44 151.8 2.4 2e-44 151.8 2.4 3.3 2 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EGF83123.1 - 6.2e-07 29.6 1.3 6.2e-07 29.6 1.3 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EGF83123.1 - 0.00059 19.9 3.7 1 9.8 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat DUF2607 PF10795.9 EGF83123.1 - 0.1 12.7 4.6 3.9 7.7 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) HEAT_EZ PF13513.6 EGF83123.1 - 4.1 8.0 6.4 10 6.8 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat F-box-like PF12937.7 EGF83124.1 - 1.3e-08 34.6 0.5 7.1e-08 32.2 0.5 2.4 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGF83124.1 - 0.0027 17.6 0.4 4.4 7.6 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat F-box PF00646.33 EGF83124.1 - 0.017 15.0 5.5 0.1 12.5 0.1 3.4 4 0 0 4 4 4 0 F-box domain Hydrolase PF00702.26 EGF83125.1 - 2.1e-09 38.0 0.4 4.6e-09 36.9 0.0 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGF83125.1 - 2.9e-07 30.7 0.2 1.6e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF5610 PF18433.1 EGF83125.1 - 0.0062 17.0 0.2 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5610) Hydrolase_like PF13242.6 EGF83125.1 - 0.047 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like zf-UBR PF02207.20 EGF83126.1 - 7.8e-11 42.0 13.8 7.8e-11 42.0 13.8 3.3 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 EGF83126.1 - 3e-06 27.0 7.2 3e-06 27.0 7.2 3.3 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 EGF83126.1 - 0.0055 16.6 0.6 0.0055 16.6 0.6 3.8 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGEF PF00621.20 EGF83127.1 - 2.4e-28 99.6 5.5 7.2e-24 85.0 1.0 3.1 3 0 0 3 3 3 2 RhoGEF domain WW PF00397.26 EGF83127.1 - 5.2e-10 39.2 1.2 1e-06 28.7 0.1 2.5 2 0 0 2 2 2 2 WW domain IQ_SEC7_PH PF16453.5 EGF83127.1 - 3.7e-08 33.4 0.1 1.6e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 PH domain PH PF00169.29 EGF83127.1 - 8.7e-07 29.4 0.0 7.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 PH domain ABC2_membrane_3 PF12698.7 EGF83129.1 - 6e-28 97.9 23.9 8.1e-28 97.5 23.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGF83129.1 - 7.9e-24 84.7 0.0 1.2e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF83129.1 - 1.9e-11 44.3 0.0 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 EGF83129.1 - 9e-08 31.8 18.6 2e-07 30.7 18.6 1.5 1 0 0 1 1 1 1 ABC-2 type transporter AAA_15 PF13175.6 EGF83129.1 - 0.023 14.4 0.0 4.4 6.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGF83129.1 - 0.024 14.4 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGF83129.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EGF83129.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF1129 PF06570.11 EGF83129.1 - 0.19 11.2 4.9 0.4 10.1 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) AAA_23 PF13476.6 EGF83129.1 - 0.2 12.1 0.0 0.34 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGF83129.1 - 0.22 10.9 0.0 17 4.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4078 PF13300.6 EGF83131.1 - 7.3e-19 67.9 5.5 7.3e-19 67.9 5.5 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4078) DUF3543 PF12063.8 EGF83132.1 - 1.4e-60 204.8 0.0 2.5e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EGF83132.1 - 2.8e-58 197.3 0.0 6.5e-58 196.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83132.1 - 3.1e-37 128.2 0.0 2.3e-36 125.4 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase XG_FTase PF03254.13 EGF83134.1 - 0.17 10.5 0.3 0.27 9.8 0.3 1.3 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Helicase_C PF00271.31 EGF83135.1 - 4e-07 30.4 0.1 1.5e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AMP-binding PF00501.28 EGF83136.1 - 1.1e-86 291.0 0.0 1.9e-86 290.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF83136.1 - 6.6e-23 81.5 0.0 1.6e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGF83136.1 - 8.6e-18 64.0 0.0 2.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF5566 PF17721.1 EGF83136.1 - 0.079 13.2 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Arm PF00514.23 EGF83137.1 - 6.8e-30 102.2 12.5 2.3e-07 30.6 0.0 9.6 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGF83137.1 - 5.3e-16 57.4 14.4 1.9 9.0 0.0 11.0 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 EGF83137.1 - 9.6e-15 54.8 4.5 0.0016 18.8 0.1 8.0 3 3 6 9 9 9 5 HEAT repeats V-ATPase_H_C PF11698.8 EGF83137.1 - 2e-10 40.8 2.9 0.23 11.6 0.0 5.6 5 1 0 5 5 5 4 V-ATPase subunit H HEAT_EZ PF13513.6 EGF83137.1 - 6.4e-06 26.6 19.6 1.6 9.3 0.2 8.5 7 3 1 8 8 8 3 HEAT-like repeat Cnd1 PF12717.7 EGF83137.1 - 4e-05 23.7 8.6 0.02 14.9 2.9 5.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EGF83137.1 - 0.0042 17.0 1.9 0.52 10.2 0.0 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF3361) CLASP_N PF12348.8 EGF83137.1 - 0.025 14.2 0.9 0.21 11.1 0.1 2.9 3 0 0 3 3 3 0 CLASP N terminal DUF383 PF04063.14 EGF83137.1 - 0.029 14.1 0.3 23 4.6 0.0 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF383) Vac14_Fab1_bd PF12755.7 EGF83137.1 - 0.029 15.0 2.9 17 6.1 0.0 4.9 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Ric8 PF10165.9 EGF83137.1 - 0.046 12.8 4.2 0.66 8.9 0.4 3.7 3 1 0 3 3 3 0 Guanine nucleotide exchange factor synembryn Proteasom_PSMB PF10508.9 EGF83137.1 - 0.17 10.4 9.3 0.02 13.4 1.0 3.0 4 1 0 4 4 4 0 Proteasome non-ATPase 26S subunit RIX1 PF08167.12 EGF83137.1 - 2.9 7.6 10.4 0.28 10.9 2.4 3.1 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Mgm101p PF06420.12 EGF83138.1 - 2.2e-80 268.2 0.0 2.4e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 RRM_1 PF00076.22 EGF83140.1 - 1.5e-78 258.6 2.4 5e-19 67.9 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGF83140.1 - 4.6e-26 90.8 0.7 1.8e-25 88.9 0.3 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EGF83140.1 - 1.4e-08 34.3 1.1 0.059 13.0 0.1 4.3 2 2 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EGF83140.1 - 0.00014 21.8 0.0 2.1 8.1 0.0 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 EGF83140.1 - 0.00049 20.1 0.5 1.4 9.1 0.1 3.9 4 0 0 4 4 4 2 Limkain b1 YflT PF11181.8 EGF83140.1 - 0.00051 20.5 2.8 0.32 11.5 1.2 2.7 2 0 0 2 2 2 2 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 EGF83140.1 - 0.0033 17.4 0.7 2.7 8.1 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGF83140.1 - 0.039 14.1 0.2 30 4.8 0.0 3.9 4 1 0 4 4 4 0 RNA recognition motif SET_assoc PF11767.8 EGF83140.1 - 0.12 12.1 0.0 8.3 6.1 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Aminotran_5 PF00266.19 EGF83141.1 - 3e-07 29.7 0.2 7.3e-07 28.5 0.2 1.7 1 1 0 1 1 1 1 Aminotransferase class-V KilA-N PF04383.13 EGF83142.1 - 2.3e-08 33.8 0.2 2.6e-07 30.5 0.2 1.9 1 1 0 1 1 1 1 KilA-N domain FragX_IP PF05994.11 EGF83143.1 - 6.4e-194 646.5 18.6 7.2e-194 646.3 16.1 2.1 2 1 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 EGF83143.1 - 4.7e-10 39.2 1.5 1.4e-09 37.7 1.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Pkinase PF00069.25 EGF83144.1 - 1.4e-72 244.2 0.1 1.6e-72 244.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83144.1 - 3.9e-43 147.6 0.0 4.6e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF83144.1 - 6e-06 25.4 0.4 8.1e-06 25.0 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGF83144.1 - 4e-05 23.3 0.7 6e-05 22.7 0.7 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGF83144.1 - 0.00094 18.6 0.6 0.016 14.5 0.4 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGF83144.1 - 0.0093 15.9 0.1 0.24 11.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF83144.1 - 0.012 15.0 0.2 0.019 14.3 0.2 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGF83144.1 - 0.067 12.0 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF5625 PF18539.1 EGF83144.1 - 0.093 13.0 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5625) Synapsin PF02078.16 EGF83144.1 - 0.12 12.7 0.3 0.47 10.8 0.3 2.0 1 1 0 1 1 1 0 Synapsin, N-terminal domain WD40 PF00400.32 EGF83145.1 - 3.3e-09 37.2 1.1 6.2 7.9 0.0 7.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83145.1 - 1.6e-05 25.1 0.0 0.27 11.5 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RabGAP-TBC PF00566.18 EGF83146.1 - 2.3e-53 181.0 0.4 3.9e-53 180.3 0.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 EGF83146.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Interleukin 34 Fmp27_SW PF10305.9 EGF83146.1 - 0.47 11.2 2.4 21 5.9 0.2 3.1 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain MOZART1 PF12554.8 EGF83147.1 - 1.2e-25 89.0 0.2 1.4e-25 88.8 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Acetyltransf_1 PF00583.25 EGF83148.1 - 5.5e-11 42.7 0.0 6.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF83148.1 - 3.4e-09 36.7 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF83148.1 - 5.7e-08 33.1 0.0 8.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF83148.1 - 1.5e-06 28.1 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGF83148.1 - 0.05 13.7 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 EGF83149.1 - 0.00024 21.2 16.0 0.00051 20.1 16.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EGF83151.1 - 2.1e-05 24.3 3.4 5.9e-05 22.9 3.4 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGF83151.1 - 0.0054 16.3 1.2 0.01 15.4 1.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-4CXXC_R1 PF10497.9 EGF83151.1 - 0.38 11.0 7.7 7.5 6.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Peptidase_M76 PF09768.9 EGF83152.1 - 1.2e-57 194.4 2.6 1.4e-57 194.2 2.6 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EGF83152.1 - 0.073 12.9 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 SprT-like family Bt_P21 PF05560.11 EGF83152.1 - 0.097 12.3 0.3 0.25 10.9 0.3 1.7 1 1 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ELMO_CED12 PF04727.13 EGF83153.1 - 6.7e-35 120.8 0.2 8.1e-35 120.5 0.2 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family CR6_interact PF10147.9 EGF83154.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Lzipper-MIP1 PF14389.6 EGF83155.1 - 0.00031 21.0 1.1 8.7 6.7 0.1 4.5 3 0 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 NPV_P10 PF05531.12 EGF83155.1 - 0.019 15.4 6.3 0.13 12.8 0.2 4.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1415 PF07209.12 EGF83155.1 - 0.023 14.4 0.6 2.1 8.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1415) DUF1515 PF07439.11 EGF83155.1 - 0.056 13.5 1.0 0.4 10.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RPN7 PF10602.9 EGF83155.1 - 0.62 9.8 9.6 1.4 8.6 0.4 3.6 3 0 0 3 3 3 0 26S proteasome subunit RPN7 CENP-F_leu_zip PF10473.9 EGF83155.1 - 0.97 9.5 12.5 3.4 7.7 0.3 4.6 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 EGF83155.1 - 0.99 9.8 8.3 35 4.9 0.7 4.7 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 EGF83155.1 - 4.1 7.6 12.1 0.12 12.5 0.7 3.5 4 0 0 4 4 4 0 Basic region leucine zipper DUF1664 PF07889.12 EGF83155.1 - 4.9 7.2 12.0 14 5.7 0.3 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EGF83155.1 - 5.3 7.1 14.0 0.62 10.1 3.8 3.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding UQ_con PF00179.26 EGF83156.1 - 2e-46 157.1 0.2 2.2e-46 157.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGF83156.1 - 0.00039 20.1 0.0 0.00046 19.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGF83156.1 - 0.003 17.8 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EGF83156.1 - 0.043 13.7 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 UEV domain DHHC PF01529.20 EGF83157.1 - 0.007 16.5 16.3 0.019 15.1 1.4 2.9 1 1 2 3 3 3 2 DHHC palmitoyltransferase DUF4802 PF16060.5 EGF83157.1 - 0.023 14.8 0.1 0.023 14.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4802) CRT10 PF08728.10 EGF83158.1 - 0.033 12.4 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 CRT10 EF-hand_7 PF13499.6 EGF83159.1 - 5.1e-21 74.9 2.8 1.3e-13 51.1 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGF83159.1 - 6.5e-20 69.1 2.8 1.3e-05 24.4 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGF83159.1 - 2.2e-18 64.5 1.0 4.3e-05 23.1 0.0 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGF83159.1 - 1.7e-12 46.2 3.1 5e-05 22.6 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGF83159.1 - 1.2e-11 44.2 7.7 4e-06 26.6 0.1 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGF83159.1 - 9.7e-08 31.9 1.1 0.13 12.3 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand VCBS PF13517.6 EGF83159.1 - 0.0011 19.5 1.5 2.9 8.6 0.1 3.2 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SPARC_Ca_bdg PF10591.9 EGF83159.1 - 0.0044 17.3 0.1 0.39 11.0 0.1 2.8 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region FG-GAP PF01839.23 EGF83159.1 - 0.07 13.3 3.7 29 4.9 0.0 3.4 3 0 0 3 3 3 0 FG-GAP repeat DUF4449 PF14613.6 EGF83161.1 - 4.1e-05 23.7 0.2 8.2e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) CRAL_TRIO PF00650.20 EGF83161.1 - 0.062 13.0 0.7 0.81 9.4 0.1 2.5 2 0 0 2 2 2 0 CRAL/TRIO domain LRR_9 PF14580.6 EGF83162.1 - 1.1e-13 51.0 6.3 1.6e-13 50.5 3.5 2.4 2 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGF83162.1 - 2.9e-09 37.1 15.9 0.00011 22.5 4.9 4.0 1 1 5 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF83162.1 - 1.3e-08 34.5 9.4 3.2e-08 33.2 5.5 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EGF83162.1 - 0.00014 21.6 2.7 3.9 7.8 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat FTA4 PF13093.6 EGF83162.1 - 0.0089 15.9 0.7 0.0089 15.9 0.7 1.9 2 1 0 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CtaG_Cox11 PF04442.14 EGF83163.1 - 1.3e-57 194.1 0.1 2.1e-57 193.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Nfu_N PF08712.11 EGF83164.1 - 1.4e-29 102.0 0.0 3.3e-29 100.8 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGF83164.1 - 1.8e-27 95.3 0.1 2.8e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Ribosomal_L3 PF00297.22 EGF83165.1 - 1.6e-186 619.7 7.2 1.8e-186 619.5 7.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Tho1_MOS11_C PF18592.1 EGF83165.1 - 0.13 12.1 0.2 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain NleF_casp_inhib PF16809.5 EGF83166.1 - 0.21 11.5 9.6 0.71 9.8 1.9 2.8 1 1 1 2 2 2 0 NleF caspase inhibitor Fib_alpha PF08702.10 EGF83166.1 - 0.45 10.7 19.1 0.051 13.8 13.3 2.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EGF83166.1 - 0.96 8.3 22.2 27 3.5 22.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Methyltransf_5 PF01795.19 EGF83167.1 - 2.7e-66 224.2 4.6 1e-56 192.7 0.6 3.0 2 1 0 2 2 2 2 MraW methylase family Methyltransf_31 PF13847.6 EGF83167.1 - 0.00083 19.2 0.1 0.043 13.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF83167.1 - 0.01 16.5 0.1 0.084 13.6 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGF83167.1 - 0.016 15.9 0.0 10 6.8 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGF83167.1 - 0.099 13.4 0.1 43 4.9 0.0 3.6 3 0 0 3 3 3 0 Methyltransferase domain TPR_2 PF07719.17 EGF83168.1 - 6.8e-25 85.1 10.6 0.0027 17.7 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_9 PF13371.6 EGF83168.1 - 7.2e-21 74.1 4.8 2.7e-07 30.6 0.1 6.1 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGF83168.1 - 1.3e-20 72.3 16.1 0.023 14.5 0.0 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGF83168.1 - 9.8e-19 67.7 1.9 0.0053 17.4 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGF83168.1 - 1.4e-18 66.3 15.5 0.00088 18.9 0.0 7.9 6 2 3 9 9 9 4 TPR repeat TPR_19 PF14559.6 EGF83168.1 - 6.6e-13 49.0 13.0 1.8e-05 25.1 1.5 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGF83168.1 - 2e-11 43.7 7.1 0.42 11.5 0.2 6.9 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF83168.1 - 3.4e-11 43.3 8.7 1.4e-06 28.5 0.3 6.6 6 3 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF83168.1 - 2.3e-09 37.0 5.0 0.004 17.4 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF83168.1 - 3e-08 33.3 15.0 0.17 12.2 0.1 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGF83168.1 - 1.3e-07 31.9 4.0 0.0021 18.3 0.0 5.1 4 1 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF83168.1 - 0.00028 21.1 10.7 2.7 8.3 0.3 5.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGF83168.1 - 0.0023 17.4 0.5 0.0023 17.4 0.5 2.4 3 0 0 3 3 3 1 MalT-like TPR region ANAPC5 PF12862.7 EGF83168.1 - 0.0037 17.3 0.7 0.53 10.4 0.2 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 EGF83168.1 - 0.0056 16.5 1.2 0.83 9.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF83168.1 - 0.024 14.6 2.9 4.2 7.6 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF83168.1 - 0.036 14.7 8.8 31 5.5 0.1 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGF83168.1 - 0.055 13.5 0.3 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TOM20_plant PF06552.12 EGF83168.1 - 0.16 11.7 2.3 7.9 6.2 0.3 3.6 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.6 EGF83168.1 - 2.3 8.4 5.5 2.2 8.4 0.3 3.6 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TRAPP PF04051.16 EGF83169.1 - 2e-44 150.9 0.0 2.3e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SpoU_methylase PF00588.19 EGF83170.1 - 1.2e-26 93.6 0.0 2.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGF83170.1 - 7.3e-08 32.6 0.0 7.7e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding ORC2 PF04084.14 EGF83171.1 - 1.8e-108 362.4 5.4 3.2e-108 361.6 5.4 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Ada3 PF10198.9 EGF83172.1 - 2.8e-25 89.0 1.3 9e-25 87.3 1.3 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 CENP-K PF11802.8 EGF83172.1 - 0.089 12.3 2.8 0.15 11.6 2.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Proteasome PF00227.26 EGF83173.1 - 1.5e-50 171.3 0.1 1.5e-50 171.3 0.1 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EGF83173.1 - 3.4e-13 49.0 0.2 5.9e-13 48.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Dehydratase_MU PF02288.15 EGF83173.1 - 0.12 12.2 0.2 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Dehydratase medium subunit CH PF00307.31 EGF83174.1 - 3.6e-14 52.9 0.2 5.8e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 EGF83174.1 - 0.016 14.8 2.7 0.016 14.8 2.7 2.0 2 0 0 2 2 2 0 Calponin family repeat 4HBT PF03061.22 EGF83175.1 - 7.2e-12 45.5 0.7 1.9e-11 44.1 0.1 1.8 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGF83175.1 - 0.04 14.2 0.0 0.048 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 EGF83175.1 - 0.059 13.5 0.1 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) NAD_Gly3P_dh_N PF01210.23 EGF83177.1 - 1.2e-50 171.6 0.3 1.8e-50 171.0 0.3 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EGF83177.1 - 2.8e-48 163.8 0.2 5.7e-48 162.8 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EGF83177.1 - 0.019 15.5 0.7 5 7.8 0.0 2.9 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Ran-binding PF05508.11 EGF83177.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein WD40 PF00400.32 EGF83178.1 - 1e-34 118.0 20.4 0.00042 21.1 0.0 11.2 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83178.1 - 0.00097 19.4 0.3 12 6.2 0.1 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGF83178.1 - 0.0085 14.9 2.6 0.24 10.1 0.1 4.3 3 1 0 4 4 4 1 Nup133 N terminal like Yae1_N PF09811.9 EGF83179.1 - 6.4e-08 32.2 2.4 9.9e-08 31.6 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF4524 PF15025.6 EGF83180.1 - 7.1e-08 32.3 3.6 2.4e-07 30.6 1.7 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4520 PF15016.6 EGF83181.1 - 1.2e-22 79.7 0.0 3.2e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) JmjN PF02375.17 EGF83181.1 - 0.2 11.7 0.1 18 5.4 0.1 2.3 2 0 0 2 2 2 0 jmjN domain VMA21 PF09446.10 EGF83182.1 - 3.3e-08 33.5 13.1 5.9e-08 32.7 13.1 1.4 1 1 0 1 1 1 1 VMA21-like domain Renin_r PF07850.14 EGF83182.1 - 0.0079 16.8 0.1 0.028 15.0 0.0 1.7 2 0 0 2 2 2 1 Renin receptor-like protein NrsF PF06532.11 EGF83182.1 - 0.027 14.2 0.1 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 Negative regulator of sigma F SPC25 PF06703.11 EGF83183.1 - 2.1e-35 121.9 0.0 2.5e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_1 PF00076.22 EGF83184.1 - 2.1e-13 49.9 0.0 3.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GREB1 PF15782.5 EGF83184.1 - 5.5 4.0 11.7 5.7 3.9 11.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPTA PF01239.22 EGF83185.1 - 1.8e-17 62.4 14.4 0.001 18.7 0.0 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat W2 PF02020.18 EGF83186.1 - 3.4e-18 65.5 0.1 8.6e-18 64.3 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EGF83186.1 - 1.9e-09 36.9 15.0 0.0017 18.0 1.8 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EGF83186.1 - 3.2e-09 36.7 0.2 5e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EGF83186.1 - 1.4e-05 23.5 4.1 0.00011 20.5 4.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EGF83186.1 - 0.00031 21.1 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGF83186.1 - 0.004 16.9 19.5 0.057 13.2 2.6 3.5 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Asp PF00026.23 EGF83187.1 - 8.5e-13 48.4 0.2 1.4e-12 47.7 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 EGF83187.1 - 0.00022 21.7 0.0 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGF83187.1 - 0.0085 16.7 0.1 0.046 14.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EGF83187.1 - 0.022 14.5 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DEAD PF00270.29 EGF83188.1 - 7.5e-39 133.3 2.4 4.5e-38 130.8 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF83188.1 - 5e-33 113.8 0.3 2.2e-31 108.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF83188.1 - 7.7e-09 35.8 0.0 2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGF83188.1 - 0.021 15.1 0.2 0.06 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EGF83188.1 - 0.061 13.3 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 EGF83188.1 - 0.073 13.4 0.8 1.3 9.3 0.8 2.4 1 1 0 1 1 1 0 AAA domain Kinetochor_Ybp2 PF08568.10 EGF83189.1 - 5.6e-12 45.0 4.1 7.9e-07 27.9 0.6 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin WD40 PF00400.32 EGF83190.1 - 1.7e-26 92.0 6.8 2e-06 28.4 0.4 6.0 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83190.1 - 2.2e-17 63.1 0.0 0.00014 22.1 0.1 4.9 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGF83190.1 - 0.0029 17.2 0.3 0.1 12.2 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain cobW PF02492.19 EGF83191.1 - 1.7e-49 167.8 0.2 2.5e-49 167.2 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGF83191.1 - 2.4e-13 49.8 0.0 4.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGF83191.1 - 0.047 13.6 1.0 6.4 6.6 0.2 2.5 2 1 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGF83191.1 - 0.064 13.0 0.2 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGF83191.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGF83191.1 - 0.071 12.1 0.4 6.5 5.7 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB YwpF PF14183.6 EGF83191.1 - 0.1 12.6 0.8 0.27 11.3 0.8 1.7 1 0 0 1 1 1 0 YwpF-like protein AAA_22 PF13401.6 EGF83191.1 - 0.12 12.6 0.1 0.81 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGF83191.1 - 0.15 11.8 0.1 7.1 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGF83191.1 - 0.16 11.7 1.2 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DNA_pol_phi PF04931.13 EGF83192.1 - 1.2e-176 589.2 19.9 1.2e-176 589.2 19.9 1.7 2 0 0 2 2 2 1 DNA polymerase phi ORC5_C PF14630.6 EGF83192.1 - 0.0033 17.0 0.2 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Telomere_reg-2 PF10193.9 EGF83192.1 - 0.8 10.2 6.3 10 6.6 0.1 4.2 4 0 0 4 4 4 0 Telomere length regulation protein BUD22 PF09073.10 EGF83192.1 - 5.3 6.3 20.3 0.088 12.1 9.2 2.8 3 0 0 3 3 3 0 BUD22 Tubulin PF00091.25 EGF83193.1 - 1.2e-69 234.5 0.0 2.4e-69 233.5 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGF83193.1 - 1.8e-43 147.7 0.1 2.8e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGF83193.1 - 2.1e-05 24.8 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGF83193.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGF83193.1 - 0.018 14.3 0.0 0.055 12.6 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Fungal_trans PF04082.18 EGF83195.1 - 3.6e-09 36.0 0.8 8.2e-09 34.9 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGF83195.1 - 8.1e-09 35.5 10.3 1.7e-08 34.5 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ESCRT-II PF05871.12 EGF83196.1 - 2.2e-47 160.8 0.1 2.2e-46 157.6 0.0 1.9 1 1 1 2 2 2 1 ESCRT-II complex subunit ETF PF01012.21 EGF83197.1 - 1.3e-37 129.4 8.0 1.9e-37 128.9 8.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGF83197.1 - 2.7e-35 120.3 1.0 2.7e-35 120.3 1.0 3.0 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain RrnaAD PF00398.20 EGF83198.1 - 5.1e-39 133.9 0.0 6.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Kinesin PF00225.23 EGF83199.1 - 2.3e-108 362.1 0.4 2.3e-108 362.1 0.4 2.7 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGF83199.1 - 3e-24 85.7 0.2 2.3e-23 82.8 0.2 2.6 1 0 0 1 1 1 1 Microtubule binding Hexapep PF00132.24 EGF83200.1 - 2.8e-10 39.5 13.0 1.7e-05 24.4 2.0 5.0 3 1 1 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGF83200.1 - 2.1e-07 30.5 4.4 4.4e-05 23.1 0.5 4.0 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGF83200.1 - 0.057 12.3 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Chordopox_A20R PF05941.13 EGF83200.1 - 0.078 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A20R protein MDD_C PF18376.1 EGF83201.1 - 9.5e-74 247.2 0.0 1.3e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGF83201.1 - 1.9e-07 31.2 0.5 4.9e-07 29.9 0.5 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Peptidase_M50 PF02163.22 EGF83201.1 - 2e-06 27.3 0.0 5.2e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 EGF83201.1 - 0.0039 17.0 0.1 0.0039 17.0 0.1 2.7 4 0 0 4 4 4 1 PDZ domain PDZ_2 PF13180.6 EGF83201.1 - 0.14 12.5 0.1 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 PDZ domain SSXT PF05030.12 EGF83203.1 - 2.7e-15 55.7 2.0 2.7e-15 55.7 2.0 2.7 2 1 0 2 2 2 1 SSXT protein (N-terminal region) MAT1 PF06391.13 EGF83203.1 - 2.3 8.0 12.2 6.8 6.5 12.2 1.8 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MCU PF04678.13 EGF83203.1 - 4.8 7.2 7.6 12 6.0 7.6 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Mannosyl_trans3 PF11051.8 EGF83204.1 - 2.3e-20 73.1 0.0 5.5e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative GST_C_3 PF14497.6 EGF83206.1 - 4.3e-14 52.5 0.0 1.1e-13 51.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGF83206.1 - 1.8e-08 34.6 0.0 1e-07 32.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGF83206.1 - 1.9e-05 25.0 0.0 4.5e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGF83206.1 - 3.6e-05 23.7 0.0 6.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGF83206.1 - 0.00013 22.1 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGF83206.1 - 0.0013 18.9 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGF83206.1 - 0.0087 16.6 0.1 0.014 15.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGF83206.1 - 0.18 12.6 0.0 0.51 11.1 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain DCP2 PF05026.13 EGF83208.1 - 5.5e-31 106.7 2.1 8.8e-31 106.1 2.1 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGF83208.1 - 5.5e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain PRKCSH-like PF12999.7 EGF83209.1 - 3.7e-25 88.7 4.3 4.5e-25 88.4 4.3 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 EGF83209.1 - 0.00035 20.7 18.1 0.0042 17.3 1.8 2.3 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF5602 PF18197.1 EGF83210.1 - 0.1 13.1 0.3 19 5.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5602) Pheromone PF08015.11 EGF83211.1 - 0.22 12.6 7.1 0.18 12.9 0.8 2.7 2 0 0 2 2 2 0 Fungal mating-type pheromone Aldo_ket_red PF00248.21 EGF83212.1 - 1e-78 264.5 0.0 1.1e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 EGF83213.1 - 9.5e-31 105.9 0.0 1.9e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGF83213.1 - 6.8e-21 74.1 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGF83213.1 - 1.4e-09 38.6 0.0 2.3e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGF83213.1 - 4.4e-07 30.2 0.0 0.0049 17.0 0.0 2.9 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGF83213.1 - 0.061 12.9 0.4 0.62 9.7 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Cornichon PF03311.14 EGF83214.1 - 1.7e-48 163.9 15.2 2.2e-48 163.6 15.2 1.0 1 0 0 1 1 1 1 Cornichon protein Bac_export_2 PF01312.19 EGF83214.1 - 1.2 8.3 5.0 1.7 7.8 5.0 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DHHC PF01529.20 EGF83214.1 - 7.4 6.7 12.5 0.26 11.4 4.2 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase FLILHELTA PF10306.9 EGF83215.1 - 4.3e-12 46.3 0.1 7.8e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EGF83215.1 - 0.001 19.6 0.2 0.0017 18.9 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MBDa PF16564.5 EGF83215.1 - 0.018 15.2 0.2 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 p55-binding region of Methyl-CpG-binding domain proteins MBD Phlebovirus_NSM PF07246.11 EGF83216.1 - 0.92 8.8 4.4 1.7 8.0 4.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SurA_N PF09312.11 EGF83216.1 - 3.3 7.8 8.1 0.27 11.3 0.7 2.6 3 0 0 3 3 3 0 SurA N-terminal domain Tcp11 PF05794.13 EGF83217.1 - 1.4e-93 314.4 11.6 1.6e-93 314.2 11.6 1.0 1 0 0 1 1 1 1 T-complex protein 11 DndE PF08870.11 EGF83217.1 - 0.047 13.9 0.1 0.25 11.6 0.1 2.2 2 0 0 2 2 2 0 DNA sulphur modification protein DndE RNase_J_C PF17770.1 EGF83217.1 - 0.28 12.3 2.1 14 6.9 0.1 3.3 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain SANTA PF09133.10 EGF83218.1 - 1.6e-18 67.0 0.7 7.8e-18 64.7 0.2 2.4 2 0 0 2 2 2 1 SANTA (SANT Associated) Methyltransf_15 PF09445.10 EGF83220.1 - 2.5e-44 150.8 0.1 3.4e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EGF83220.1 - 5.3e-08 32.8 0.0 9.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EGF83220.1 - 1.1e-07 31.7 0.1 6.5e-07 29.2 0.1 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EGF83220.1 - 3.8e-07 30.7 0.0 7.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF83220.1 - 0.00022 21.0 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF83220.1 - 0.00051 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGF83220.1 - 0.00076 19.4 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF83220.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EGF83220.1 - 0.0021 17.7 0.1 0.0048 16.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.13 EGF83220.1 - 0.0027 17.2 0.3 0.0053 16.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Rota_NS26 PF01525.16 EGF83220.1 - 0.032 14.2 0.9 0.055 13.5 0.9 1.3 1 0 0 1 1 1 0 Rotavirus NS26 Methyltransf_3 PF01596.17 EGF83220.1 - 0.098 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase BRICHOS PF04089.14 EGF83221.1 - 0.016 15.4 3.7 0.02 15.1 0.1 2.9 3 0 0 3 3 3 0 BRICHOS domain TRAPP PF04051.16 EGF83222.1 - 2.5e-41 140.8 0.0 2.9e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TM140 PF14985.6 EGF83223.1 - 0.028 14.0 0.7 0.047 13.2 0.7 1.3 1 0 0 1 1 1 0 TM140 protein family AWS PF17907.1 EGF83224.1 - 0.028 14.4 0.3 0.028 14.4 0.3 2.6 2 1 0 2 2 2 0 AWS domain DUF2203 PF09969.9 EGF83224.1 - 0.18 12.5 0.9 0.28 11.9 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PBP1_TM PF14812.6 EGF83224.1 - 3.9 7.9 9.1 6.8 7.1 9.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_PEP_C PF04513.12 EGF83225.1 - 0.13 12.3 0.2 0.13 12.3 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 EGF83225.1 - 0.69 10.0 13.2 0.93 9.6 0.3 4.2 3 2 0 3 3 3 0 Protein of unknown function (DUF2730) IBN_N PF03810.19 EGF83226.1 - 9.4e-07 28.7 0.0 3.2e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGF83226.1 - 7e-06 26.2 0.0 7e-06 26.2 0.0 4.1 5 0 0 5 5 5 1 Exportin 1-like protein YEATS PF03366.16 EGF83227.1 - 1.2e-31 108.5 0.1 2.2e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 YEATS family TFIID-31kDa PF02291.15 EGF83228.1 - 0.15 12.1 2.2 0.54 10.3 0.2 2.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit C2 PF00168.30 EGF83229.1 - 1.4e-25 89.5 0.0 2.8e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 EGF83229.1 - 0.001 19.7 0.0 7.4 7.3 0.0 4.4 4 0 0 4 4 4 2 Putative heavy-metal-binding SPC12 PF06645.13 EGF83230.1 - 1.9e-24 85.5 0.2 2.5e-24 85.1 0.2 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) AAA PF00004.29 EGF83231.1 - 4.5e-28 98.3 0.0 6.2e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF83231.1 - 5.2e-08 33.5 0.1 9.2e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF83231.1 - 1.1e-07 32.2 0.2 2.6e-07 31.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF83231.1 - 6.3e-06 26.8 0.0 9.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGF83231.1 - 8.9e-05 22.7 0.0 0.00013 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGF83231.1 - 0.00014 21.9 0.4 0.007 16.3 0.4 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EGF83231.1 - 0.00049 20.1 0.3 0.0011 18.9 0.3 1.7 1 1 0 1 1 1 1 NACHT domain RuvB_N PF05496.12 EGF83231.1 - 0.00059 19.6 0.3 0.0098 15.6 0.0 2.3 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGF83231.1 - 0.00065 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGF83231.1 - 0.00078 19.5 0.0 0.003 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGF83231.1 - 0.0011 18.2 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EGF83231.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGF83231.1 - 0.0018 18.8 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGF83231.1 - 0.0026 17.4 0.1 0.013 15.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 EGF83231.1 - 0.0029 17.0 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.6 EGF83231.1 - 0.0032 17.7 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGF83231.1 - 0.0052 16.8 0.2 0.015 15.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGF83231.1 - 0.0054 16.5 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EGF83231.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CPT PF07931.12 EGF83231.1 - 0.0071 16.2 0.0 0.034 14.0 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 EGF83231.1 - 0.0076 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.18 EGF83231.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGF83231.1 - 0.0089 16.5 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.17 EGF83231.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CLP1_P PF16575.5 EGF83231.1 - 0.014 15.2 0.0 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_11 PF13086.6 EGF83231.1 - 0.015 15.1 0.1 0.032 14.0 0.0 1.5 1 1 0 2 2 1 0 AAA domain AAA_19 PF13245.6 EGF83231.1 - 0.016 15.6 0.2 0.075 13.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGF83231.1 - 0.019 15.4 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGF83231.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EGF83231.1 - 0.029 14.1 0.1 0.056 13.2 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase cobW PF02492.19 EGF83231.1 - 0.031 13.9 0.1 0.093 12.3 0.0 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 EGF83231.1 - 0.032 13.7 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.15 EGF83231.1 - 0.033 14.1 0.2 0.082 12.8 0.2 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGF83231.1 - 0.036 14.0 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_2 PF07724.14 EGF83231.1 - 0.037 14.2 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_13 PF13166.6 EGF83231.1 - 0.04 12.6 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EGF83231.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 EGF83231.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGF83231.1 - 0.047 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 EGF83231.1 - 0.053 13.3 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 EGF83231.1 - 0.063 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGF83231.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SRP54 PF00448.22 EGF83231.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 EGF83231.1 - 0.09 12.8 0.0 1.8 8.6 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 EGF83231.1 - 0.097 11.9 0.2 11 5.2 0.4 2.2 1 1 1 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 EGF83231.1 - 0.12 11.7 0.4 1.1 8.5 0.0 2.0 1 1 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 EGF83231.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.11 EGF83231.1 - 0.14 12.1 0.1 0.86 9.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGF83231.1 - 0.17 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 EGF83231.1 - 0.26 10.5 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CLTH PF10607.9 EGF83232.1 - 2.3e-39 134.6 2.0 3.3e-39 134.2 2.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGF83232.1 - 5.3e-10 38.9 0.4 1.6e-09 37.4 0.1 2.0 2 0 0 2 2 2 1 LisH CSN8_PSD8_EIF3K PF10075.9 EGF83233.1 - 8.3e-31 106.9 0.1 1.2e-30 106.4 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGF83233.1 - 3e-06 26.8 0.1 3.8e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP family Pkinase PF00069.25 EGF83234.1 - 5.4e-36 124.3 0.0 7.4e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83234.1 - 5.7e-29 101.2 0.0 8.3e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF83234.1 - 8.1e-07 28.6 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGF83234.1 - 0.0013 18.1 0.3 0.0023 17.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGF83234.1 - 0.014 15.0 0.4 0.043 13.4 0.4 1.7 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 EGF83234.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGF83234.1 - 0.13 11.0 0.7 0.19 10.5 0.7 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L27A PF00828.19 EGF83235.1 - 7.9e-20 71.8 0.0 1.2e-19 71.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SAP30_Sin3_bdg PF13867.6 EGF83236.1 - 8.1e-14 51.7 0.3 2.2e-13 50.3 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 APG9 PF04109.16 EGF83237.1 - 3.9e-182 606.6 11.8 4.5e-182 606.3 11.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Histone PF00125.24 EGF83238.1 - 9.1e-19 68.1 0.0 1.2e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF83238.1 - 1.7e-06 28.2 0.0 2.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGF83238.1 - 0.00037 20.9 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGF83238.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein Aminotran_1_2 PF00155.21 EGF83239.1 - 6.6e-56 190.0 0.0 7.4e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sec15 PF04091.12 EGF83240.1 - 4.8e-84 282.4 3.6 4.8e-84 282.4 3.6 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 EGF83240.1 - 0.0018 18.5 0.2 0.008 16.3 0.2 2.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COG2 PF06148.11 EGF83240.1 - 0.021 14.9 4.5 0.023 14.8 0.4 3.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 VGPC1_C PF16799.5 EGF83240.1 - 0.049 13.6 0.5 0.14 12.1 0.5 1.7 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Sec8_exocyst PF04048.14 EGF83240.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Sec5 PF15469.6 EGF83240.1 - 0.41 10.4 6.0 0.082 12.7 0.9 2.5 3 0 0 3 3 3 0 Exocyst complex component Sec5 Kinesin PF00225.23 EGF83241.1 - 1e-93 313.9 0.4 1.2e-93 313.7 0.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF83241.1 - 1.2e-16 61.0 0.0 2.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Cyclin PF08613.11 EGF83242.1 - 2.6e-32 112.4 10.4 5e-23 82.2 0.1 3.7 4 0 0 4 4 4 2 Cyclin URO-D PF01208.17 EGF83243.1 - 1.2e-131 439.0 0.0 1.4e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TPMT PF05724.11 EGF83244.1 - 1.4e-34 119.7 0.0 1.6e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EGF83244.1 - 1.1e-09 38.9 0.0 2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF83244.1 - 2.3e-09 37.2 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF83244.1 - 1.8e-07 31.7 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF83244.1 - 2.2e-05 25.1 0.0 3.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF83244.1 - 8.8e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGF83244.1 - 0.22 10.9 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_24 PF18404.1 EGF83245.1 - 5.3e-147 488.4 1.1 9.7e-147 487.5 1.1 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGF83245.1 - 9.9e-51 173.1 0.1 5.5e-47 160.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EGF83245.1 - 3.2e-36 125.0 0.6 7.1e-36 123.9 0.6 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGF83245.1 - 1.5e-35 121.6 0.0 4.6e-35 120.0 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 EGF83245.1 - 1.3e-32 112.5 0.2 5.4e-32 110.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EGF83245.1 - 7.7e-30 104.4 0.4 1.1e-25 90.9 0.7 3.0 4 0 0 4 4 4 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EGF83245.1 - 1.5e-05 24.7 0.5 6.5e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 8 Phage_XkdX PF09693.10 EGF83245.1 - 0.22 11.6 0.9 0.89 9.6 0.0 2.3 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) zf-RING_2 PF13639.6 EGF83246.1 - 0.0028 17.9 4.3 0.0028 17.9 4.3 2.4 3 0 0 3 3 3 1 Ring finger domain C1_1 PF00130.22 EGF83246.1 - 0.0061 16.4 1.1 0.018 14.9 1.1 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SWIM PF04434.17 EGF83246.1 - 0.0083 15.8 0.3 0.018 14.7 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.29 EGF83246.1 - 0.024 14.5 4.0 0.024 14.5 4.0 1.9 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 EGF83247.1 - 5e-10 39.6 3.2 1.1e-09 38.4 3.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF83247.1 - 2.1e-07 30.7 4.7 4.5e-07 29.6 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGF83247.1 - 4.2e-06 26.4 1.6 9.5e-06 25.3 1.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGF83247.1 - 1.7e-05 25.0 7.0 5e-05 23.5 7.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF83247.1 - 7.5e-05 22.5 3.9 7.5e-05 22.5 3.9 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF83247.1 - 0.00093 19.2 1.6 0.0023 17.9 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGF83247.1 - 0.0013 18.3 3.9 0.0029 17.2 3.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGF83247.1 - 0.0062 16.5 3.8 0.0062 16.5 3.8 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGF83247.1 - 0.045 13.9 0.7 0.045 13.9 0.7 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 EGF83247.1 - 0.049 13.7 2.2 0.11 12.5 2.2 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 EGF83247.1 - 0.054 13.8 5.4 0.1 13.0 5.4 1.5 1 0 0 1 1 1 0 RING-like domain Zn_Tnp_IS1595 PF12760.7 EGF83247.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_UBOX PF13445.6 EGF83247.1 - 0.34 11.0 5.9 0.87 9.7 5.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF83247.1 - 1.6 8.6 7.7 0.094 12.6 2.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) S-AdoMet_synt_C PF02773.16 EGF83248.1 - 1.1e-68 229.5 0.7 2e-68 228.7 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGF83248.1 - 1.4e-45 154.4 0.0 2.9e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGF83248.1 - 9.9e-45 151.3 0.2 2.1e-44 150.2 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGF83248.1 - 0.042 12.6 0.5 0.15 10.8 0.2 1.8 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Iso_dh PF00180.20 EGF83249.1 - 4.6e-77 259.5 0.0 5.4e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyoxalase PF00903.25 EGF83250.1 - 1.4e-22 80.3 1.1 3.6e-16 59.5 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGF83250.1 - 2.9e-11 43.6 0.2 0.00027 21.2 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGF83250.1 - 3.3e-05 24.1 0.1 1.1 9.3 0.1 3.6 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EGF83250.1 - 0.00022 21.4 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF2283 PF10049.9 EGF83250.1 - 0.013 15.8 0.1 0.036 14.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Nop PF01798.18 EGF83251.1 - 4.9e-88 294.5 0.0 9.4e-88 293.5 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGF83251.1 - 9.2e-12 45.2 3.1 1.4e-11 44.6 0.0 2.8 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 EGF83251.1 - 1.2 9.1 28.5 2.2 8.3 28.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TFIIA PF03153.13 EGF83252.1 - 4e-46 158.9 13.6 1.3e-35 124.3 10.5 2.1 1 1 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 EGF83252.1 - 0.0076 16.0 6.0 0.01 15.6 6.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGF83252.1 - 1.4 6.9 7.6 1.8 6.5 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ran-binding PF05508.11 EGF83254.1 - 2e-54 184.7 1.7 1.5e-53 181.8 0.1 2.6 2 1 0 2 2 2 1 RanGTP-binding protein GRAM PF02893.20 EGF83255.1 - 1.9e-29 101.8 8.9 6.3e-20 71.2 1.1 3.6 3 1 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EGF83255.1 - 3.4e-24 85.5 0.0 6.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EGF83255.1 - 1e-10 42.0 1.3 6.6e-10 39.4 0.1 2.4 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 EGF83255.1 - 9.7e-06 24.6 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SIN1_PH PF16979.5 EGF83255.1 - 0.015 15.6 1.7 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PH_3 PF14593.6 EGF83255.1 - 0.034 14.3 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 0 PH domain PH_6 PF15406.6 EGF83255.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 EGF83255.1 - 0.18 12.1 0.3 12 6.3 0.0 2.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region DUF3510 PF12022.8 EGF83256.1 - 1.5 9.2 6.7 0.29 11.5 0.8 2.7 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) Pentapeptide_2 PF01469.18 EGF83257.1 - 0.42 10.6 4.9 0.62 10.0 4.9 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Collagen PF01391.18 EGF83258.1 - 0.015 15.0 51.3 4.2 7.2 51.3 2.2 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) SRP-alpha_N PF04086.13 EGF83258.1 - 8.6 6.2 11.3 9.3 6.1 11.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TubC_N PF18563.1 EGF83260.1 - 0.058 13.4 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 TubC N-terminal docking domain MSSP PF03940.13 EGF83260.1 - 0.37 10.4 31.2 0.36 10.5 8.9 3.2 1 1 1 2 2 2 0 Male specific sperm protein CPSF100_C PF13299.6 EGF83261.1 - 7.8 6.7 7.7 15 5.8 7.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 EGF83262.1 - 6 6.8 28.3 7.8 6.4 28.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 EGF83263.1 - 0.013 13.9 0.1 0.018 13.5 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 EGF83263.1 - 0.02 15.8 0.2 0.063 14.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Fasciclin PF02469.22 EGF83264.1 - 3e-28 98.6 2.2 4.3e-16 59.3 0.0 2.9 2 1 0 2 2 2 2 Fasciclin domain TPR_1 PF00515.28 EGF83265.1 - 1.9e-20 71.8 6.3 8.3e-05 22.2 0.0 8.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGF83265.1 - 3.4e-19 67.3 10.0 7e-05 22.6 0.0 9.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGF83265.1 - 6.1e-16 58.5 2.9 2.1e-07 31.2 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF83265.1 - 2.4e-13 49.2 5.3 0.13 12.5 0.1 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF83265.1 - 5e-13 49.1 13.4 2.3e-10 40.5 0.4 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGF83265.1 - 6.6e-11 41.4 1.2 0.002 18.1 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGF83265.1 - 8.9e-11 42.1 3.3 0.34 11.5 0.0 7.4 5 1 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGF83265.1 - 2.1e-10 41.0 2.8 0.13 12.9 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGF83265.1 - 2.3e-09 36.8 1.2 0.00043 20.1 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF83265.1 - 6e-07 29.7 2.8 0.55 11.2 0.0 6.4 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGF83265.1 - 2.1e-05 24.1 0.0 4.1 7.2 0.0 6.0 4 2 2 6 6 6 1 TPR repeat TPR_6 PF13174.6 EGF83265.1 - 0.00069 20.1 6.1 0.033 14.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF83265.1 - 0.0007 19.8 6.0 1.3 9.5 0.1 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF83265.1 - 0.01 15.2 1.1 0.17 11.2 0.0 3.2 4 1 0 4 4 4 0 MalT-like TPR region TPR_9 PF13371.6 EGF83265.1 - 0.068 13.3 0.3 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF83265.1 - 0.2 11.7 0.1 0.2 11.7 0.1 4.3 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EGF83265.1 - 1 9.4 11.0 5.6 7.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC14 PF08045.11 EGF83266.1 - 1.8e-13 50.3 0.1 2.4e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component IFRD PF05004.13 EGF83266.1 - 0.008 15.3 2.0 0.13 11.3 0.2 2.1 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 EGF83266.1 - 0.011 15.9 0.0 0.28 11.5 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat ASH PF15780.5 EGF83267.1 - 1.4e-08 34.8 0.1 4.1e-05 23.7 0.0 3.8 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MYCBPAP PF14646.6 EGF83267.1 - 0.0013 17.8 2.1 0.0021 17.1 0.1 2.4 3 0 0 3 3 3 1 MYCBP-associated protein family TMEM131_like PF12371.8 EGF83267.1 - 0.03 14.6 0.0 0.16 12.3 0.0 2.2 1 0 0 1 1 1 0 Transmembrane protein 131-like RsfS PF02410.15 EGF83267.1 - 0.16 12.5 0.3 11 6.6 0.1 2.6 2 0 0 2 2 2 0 Ribosomal silencing factor during starvation Myb_DNA-binding PF00249.31 EGF83268.1 - 4.5e-42 142.0 16.8 9.7e-13 48.1 0.1 6.0 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF83268.1 - 4e-36 123.0 5.4 1.3e-14 54.2 0.0 5.1 3 2 2 5 5 5 4 Myb-like DNA-binding domain SLIDE PF09111.10 EGF83268.1 - 3.3e-08 33.5 0.3 0.0037 17.3 0.0 4.1 3 1 1 4 4 4 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGF83268.1 - 0.0053 16.6 0.6 6 6.8 0.0 3.4 4 0 0 4 4 4 2 Myb DNA-binding like Rap1_C PF11626.8 EGF83268.1 - 0.017 15.2 1.1 8.4 6.6 0.0 4.0 3 2 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4177 PF13783.6 EGF83268.1 - 0.1 12.9 0.1 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) MADF_DNA_bdg PF10545.9 EGF83268.1 - 0.38 11.1 12.5 2.6 8.4 0.1 4.8 5 0 0 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like dsrm PF00035.26 EGF83269.1 - 6.7e-05 23.5 0.0 0.7 10.6 0.0 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Herpes_UL6 PF01763.16 EGF83270.1 - 0.0081 14.7 0.6 0.02 13.4 0.6 1.6 1 0 0 1 1 1 1 Herpesvirus UL6 like SlyX PF04102.12 EGF83270.1 - 0.084 13.5 3.1 4.6 7.9 0.7 3.0 2 0 0 2 2 2 0 SlyX T4_baseplate PF12322.8 EGF83270.1 - 5.1 6.5 9.8 6.7 6.1 1.3 2.8 2 1 1 3 3 3 0 T4 bacteriophage base plate protein APG6_N PF17675.1 EGF83270.1 - 8.3 7.0 13.3 0.086 13.4 2.1 3.2 4 0 0 4 4 4 0 Apg6 coiled-coil region HGTP_anticodon PF03129.20 EGF83271.1 - 2.6e-20 72.4 0.3 1.2e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGF83271.1 - 8.5e-11 42.1 0.0 2.6e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 EGF83271.1 - 1.3e-05 25.2 4.9 1.3e-05 25.2 4.9 2.1 2 0 0 2 2 2 1 WHEP-TRS domain LIM PF00412.22 EGF83272.1 - 1.9e-10 40.8 6.7 3.1e-10 40.1 6.7 1.3 1 0 0 1 1 1 1 LIM domain DiS_P_DiS PF06750.13 EGF83272.1 - 0.075 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-ACC PF17848.1 EGF83272.1 - 2.2 8.4 4.9 10 6.3 0.6 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Pkinase PF00069.25 EGF83273.1 - 7.6e-70 235.3 0.0 9e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83273.1 - 7.4e-42 143.4 0.0 9.3e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF83273.1 - 6.3e-07 29.0 0.0 7.9e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGF83273.1 - 9.7e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGF83273.1 - 0.00073 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF83273.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF83273.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3452 PF11934.8 EGF83275.1 - 0.007 15.9 0.4 0.013 15.1 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) CmlA_N PF18456.1 EGF83275.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Spt5_N PF11942.8 EGF83275.1 - 0.022 15.7 0.6 0.038 15.0 0.6 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal MutS_V PF00488.21 EGF83277.1 - 3.9e-63 212.9 0.2 1e-62 211.5 0.2 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGF83277.1 - 1.1e-31 110.6 1.9 2.1e-31 109.6 1.2 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGF83277.1 - 4.5e-20 72.0 0.0 8.6e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGF83277.1 - 7.7e-12 45.7 0.0 1.8e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain II RasGEF_N_2 PF14663.6 EGF83277.1 - 0.011 16.1 0.8 0.048 14.1 0.2 2.3 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GAIN_A PF18619.1 EGF83277.1 - 5.3 7.3 5.9 20 5.5 0.9 3.4 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A NUC173 PF08161.12 EGF83278.1 - 2.7e-26 92.5 0.1 6.2e-25 88.1 0.0 3.2 3 1 0 3 3 3 1 NUC173 domain Endonuc_BglI PF14562.6 EGF83278.1 - 0.0066 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease BglI HEAT PF02985.22 EGF83278.1 - 0.44 10.9 1.4 37 5.0 0.0 4.5 6 0 0 6 6 6 0 HEAT repeat adh_short PF00106.25 EGF83279.1 - 3.9e-34 117.8 0.0 1.6e-28 99.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF83279.1 - 2.2e-18 66.7 0.0 9.6e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF83279.1 - 2.6e-10 40.5 0.1 3.6e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGF83279.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 EGF83279.1 - 0.0039 16.5 0.0 0.0055 16.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 EGF83279.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGF83279.1 - 0.055 12.6 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein E1_dh PF00676.20 EGF83280.1 - 1.4e-101 339.4 0.7 1.7e-101 339.1 0.7 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGF83280.1 - 0.00012 21.9 0.2 0.0014 18.4 0.2 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGF83280.1 - 0.00047 19.5 0.0 0.0039 16.4 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Serglycin PF04360.12 EGF83282.1 - 0.4 10.6 4.2 0.97 9.4 4.2 1.6 1 0 0 1 1 1 0 Serglycin Methyltransf_23 PF13489.6 EGF83283.1 - 1e-06 28.7 0.0 7.6e-06 25.8 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF83283.1 - 9.8e-06 26.2 0.2 6.8e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF83283.1 - 0.0006 20.5 0.2 0.0081 16.8 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF83283.1 - 0.0017 18.2 0.1 0.0084 15.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF83283.1 - 0.0024 18.5 0.2 0.022 15.4 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EGF83283.1 - 0.0043 16.7 0.1 0.0077 15.8 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Peptidase_S51 PF03575.17 EGF83283.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Methyltransf_32 PF13679.6 EGF83283.1 - 0.24 11.4 0.1 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain FRB_dom PF08771.11 EGF83284.1 - 0.00021 21.7 2.3 0.065 13.6 0.1 2.3 2 0 0 2 2 2 2 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EGF83284.1 - 0.13 12.6 0.0 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EGF83284.1 - 0.14 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat PI3_PI4_kinase PF00454.27 EGF83285.1 - 2.6e-48 165.0 0.0 3e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF2536 PF10750.9 EGF83286.1 - 0.081 12.8 0.0 0.31 11.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Enkurin PF13864.6 EGF83287.1 - 1.9e-24 86.0 1.4 3.5e-24 85.1 1.4 1.5 1 0 0 1 1 1 1 Calmodulin-binding Gly_radical PF01228.21 EGF83287.1 - 0.021 15.3 0.2 0.062 13.8 0.1 1.9 2 0 0 2 2 2 0 Glycine radical SNF2_N PF00176.23 EGF83288.1 - 1.7e-51 175.0 0.9 1.5e-50 171.9 0.4 2.4 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF83288.1 - 1.9e-21 76.5 0.1 3e-20 72.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGF83288.1 - 1.1e-06 28.0 0.1 2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Clathrin PF00637.20 EGF83289.1 - 1.4e-23 83.3 0.5 2.7e-21 75.9 0.0 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EGF83289.1 - 6.4e-05 23.4 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 EGF83289.1 - 0.0044 17.8 1.1 0.018 15.9 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Swi3 PF07962.12 EGF83289.1 - 0.082 12.9 0.3 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 ANAPC4_WD40 PF12894.7 EGF83289.1 - 0.11 12.8 0.2 2 8.8 0.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 EGF83289.1 - 1.3 9.2 6.6 0.23 11.5 0.7 2.6 2 0 0 2 2 2 0 RING-type zinc-finger RecR PF02132.15 EGF83289.1 - 2.6 7.7 5.8 1.2 8.7 0.2 2.9 3 0 0 3 3 3 0 RecR protein zf-RING_5 PF14634.6 EGF83289.1 - 10 6.2 9.1 2.1 8.3 1.2 3.1 3 1 0 3 3 3 0 zinc-RING finger domain DUF676 PF05057.14 EGF83290.1 - 7.4e-09 35.4 0.3 4.2e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EGF83290.1 - 0.00011 22.0 0.5 0.00029 20.6 0.5 1.9 1 1 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EGF83290.1 - 0.0015 17.7 0.0 0.0023 17.2 0.0 1.3 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGF83290.1 - 0.033 13.7 0.1 0.086 12.3 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EGF83290.1 - 0.048 12.9 0.1 0.12 11.6 0.0 1.7 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF83290.1 - 0.05 14.2 0.6 0.13 12.9 0.9 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family bZIP_2 PF07716.15 EGF83291.1 - 4.8e-08 33.0 17.7 9.7e-08 32.0 17.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGF83291.1 - 8.7e-07 28.9 13.9 1.8e-06 28.0 13.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGF83291.1 - 0.0089 16.5 11.3 0.016 15.7 11.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Ank_4 PF13637.6 EGF83292.1 - 7.2e-23 80.7 14.1 3e-05 24.5 0.3 8.1 3 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF83292.1 - 7.6e-22 77.7 10.8 1.1e-05 26.0 0.1 5.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF83292.1 - 9.7e-20 70.4 9.7 0.022 15.1 0.0 10.3 4 2 7 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF83292.1 - 4.9e-11 41.8 8.5 3.1 8.7 0.1 10.7 10 2 2 12 12 12 1 Ankyrin repeat Ank PF00023.30 EGF83292.1 - 0.0022 18.3 2.8 5.1 7.7 0.1 5.4 4 1 0 4 4 4 1 Ankyrin repeat DUF5049 PF16468.5 EGF83292.1 - 0.014 15.3 0.0 34 4.4 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF5049) Chorion_S16 PF05836.12 EGF83292.1 - 0.091 13.0 0.9 2.1 8.6 0.0 3.4 2 1 0 3 3 3 0 Chorion protein S16 RNR_inhib PF08591.10 EGF83293.1 - 0.00011 23.5 0.0 0.00018 22.7 0.0 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Trp_halogenase PF04820.14 EGF83293.1 - 0.023 13.6 0.0 0.023 13.5 0.0 1.0 1 0 0 1 1 1 0 Tryptophan halogenase SEP PF08059.13 EGF83295.1 - 1.8e-28 98.9 0.1 5.8e-28 97.3 0.0 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EGF83295.1 - 4.3e-18 65.3 0.0 7.2e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGF83295.1 - 7.1e-15 54.6 3.4 1.4e-14 53.6 3.4 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EGF83295.1 - 2.8e-06 26.9 0.6 6.3e-06 25.7 0.6 1.6 1 0 0 1 1 1 1 TAP C-terminal domain DUF1640 PF07798.11 EGF83296.1 - 6.1e-36 124.1 10.0 8.3e-36 123.7 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4549 PF15082.6 EGF83296.1 - 0.088 12.6 2.0 0.33 10.7 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4549) FapA PF03961.13 EGF83296.1 - 0.18 10.3 6.7 1.7 7.2 5.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Sds3 PF08598.11 EGF83296.1 - 0.28 11.1 6.2 0.6 10.1 6.2 1.5 1 1 0 1 1 1 0 Sds3-like Uso1_p115_C PF04871.13 EGF83296.1 - 1 9.8 5.9 1.7 9.0 5.9 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 EGF83296.1 - 4.5 7.7 9.3 9.2 6.7 8.2 1.8 1 1 1 2 2 2 0 Fez1 COG6 PF06419.11 EGF83297.1 - 1.3e-183 611.7 10.9 1.5e-183 611.5 10.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Mu-like_Pro PF10123.9 EGF83297.1 - 0.0044 16.6 1.8 0.05 13.1 1.2 2.5 2 1 1 3 3 3 1 Mu-like prophage I protein HAD_2 PF13419.6 EGF83298.1 - 2.1e-22 80.1 0.0 2.5e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGF83298.1 - 2.8e-13 50.7 0.0 1.8e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGF83298.1 - 0.00042 20.3 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGF83298.1 - 0.016 15.3 0.0 6.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Abhydrolase_2 PF02230.16 EGF83299.1 - 1.6e-15 57.6 0.0 2.1e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGF83299.1 - 0.012 14.9 0.0 0.61 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGF83299.1 - 0.041 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 EGF83299.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Sperm_Ag_HE2 PF05324.13 EGF83300.1 - 0.15 12.6 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Sperm antigen HE2 EGF PF00008.27 EGF83300.1 - 0.59 10.5 8.7 0.54 10.6 5.4 2.2 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGF83300.1 - 1.3 9.4 11.3 0.15 12.5 6.7 1.8 2 0 0 2 2 2 0 EGF-like domain Chromate_transp PF02417.15 EGF83301.1 - 2.9e-38 131.5 35.0 1.3e-37 129.4 15.2 2.4 3 0 0 3 3 3 2 Chromate transporter DUF423 PF04241.15 EGF83301.1 - 0.59 10.4 4.9 4.2 7.7 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) CoA_binding PF02629.19 EGF83302.1 - 9.7e-29 99.9 1.6 1.1e-28 99.8 0.5 1.7 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGF83302.1 - 7.9e-24 84.2 0.1 2.1e-23 82.8 0.1 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EGF83302.1 - 7.3e-09 35.5 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGF83302.1 - 0.00038 20.9 0.1 0.0013 19.2 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain DapB_N PF01113.20 EGF83302.1 - 0.0038 17.4 0.1 0.0069 16.5 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EGF83302.1 - 0.09 13.6 0.0 0.23 12.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_trans_1_4 PF13692.6 EGF83302.1 - 0.098 13.1 0.1 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 BTB_3 PF16017.5 EGF83303.1 - 0.019 15.0 0.1 0.041 14.0 0.1 1.7 1 1 0 1 1 1 0 BTB/POZ domain DUF3888 PF13027.6 EGF83303.1 - 0.037 14.4 0.5 0.037 14.4 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3888) zf-RING_7 PF02591.15 EGF83304.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain Nuclease_act PF08133.11 EGF83305.1 - 1.2 9.5 4.1 1.1e+02 3.3 0.2 4.0 3 1 1 4 4 4 0 Anticodon nuclease activator family ERCC3_RAD25_C PF16203.5 EGF83306.1 - 2.7e-117 390.3 0.5 4.1e-117 389.7 0.5 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGF83306.1 - 1.1e-34 119.4 0.0 2.7e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF83306.1 - 1.2e-12 48.2 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGF83306.1 - 2.3e-10 40.8 0.1 5e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGF83306.1 - 7.4e-06 24.9 0.0 1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ran_BP1 PF00638.18 EGF83307.1 - 2.5e-19 69.7 0.0 4.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Myb_DNA-bind_7 PF15963.5 EGF83308.1 - 2.5e-20 72.2 0.8 3.8e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGF83308.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain PHD PF00628.29 EGF83309.1 - 3e-09 36.6 12.0 6.1e-09 35.6 12.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 EGF83309.1 - 0.022 15.1 2.2 0.095 13.1 2.2 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx zf-CW PF07496.15 EGF83309.1 - 0.034 14.2 4.8 0.094 12.8 4.8 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger RWP-RK PF02042.15 EGF83309.1 - 0.041 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 RWP-RK domain PHD_2 PF13831.6 EGF83309.1 - 0.88 9.2 7.4 1.7 8.3 7.4 1.5 1 0 0 1 1 1 0 PHD-finger PNP_UDP_1 PF01048.20 EGF83310.1 - 1.2e-42 145.8 0.1 1.4e-42 145.5 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cupin_8 PF13621.6 EGF83311.1 - 1.2e-22 80.9 0.1 8.8e-20 71.5 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGF83311.1 - 2e-12 47.5 0.3 2.4e-11 44.0 0.3 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EGF83311.1 - 0.025 14.5 0.3 0.05 13.5 0.3 1.6 1 0 0 1 1 1 0 F-box-like Cupin_4 PF08007.12 EGF83311.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein Metal_CEHH PF14455.6 EGF83311.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted metal binding domain Cupin_2 PF07883.11 EGF83311.1 - 0.18 11.5 0.0 0.64 9.8 0.0 1.8 2 0 0 2 2 2 0 Cupin domain GPI PF06560.11 EGF83311.1 - 0.22 10.8 0.1 0.4 9.9 0.1 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Adap_comp_sub PF00928.21 EGF83312.1 - 3.3e-61 207.0 0.0 4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGF83312.1 - 0.0016 18.4 0.6 0.0016 18.4 0.6 1.7 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Mucin15 PF15672.5 EGF83312.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 TMEM234 PF10639.9 EGF83313.1 - 9.7e-31 106.2 1.6 1.4e-30 105.7 1.6 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EGF83313.1 - 2.1e-06 28.0 5.3 0.00028 21.1 1.8 2.1 1 1 1 2 2 2 2 EamA-like transporter family IQ PF00612.27 EGF83314.1 - 0.0001 21.8 1.9 0.00018 21.0 0.7 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif CH PF00307.31 EGF83314.1 - 0.00022 21.3 0.0 0.00055 20.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4743 PF15916.5 EGF83315.1 - 1.4e-13 50.9 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EGF83315.1 - 3.8e-06 27.0 0.0 6.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF5427 PF10310.9 EGF83316.1 - 9.6e-12 44.6 0.0 2.9e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5427) CPSF_A PF03178.15 EGF83317.1 - 9.2e-81 271.6 0.0 2.5e-80 270.2 0.0 1.8 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 EGF83317.1 - 4.4e-28 98.2 0.0 4.4e-27 94.9 0.0 2.3 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ras PF00071.22 EGF83318.1 - 3.5e-47 160.0 1.1 4e-47 159.8 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF83318.1 - 3.9e-15 56.1 0.0 6.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF83318.1 - 1e-07 31.6 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF83318.1 - 1.7e-07 31.0 0.3 3e-06 26.9 0.2 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF83318.1 - 3.8e-05 23.6 0.6 0.0033 17.3 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EGF83318.1 - 0.00029 20.4 0.2 0.0035 16.9 0.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGF83318.1 - 0.00053 20.1 0.1 0.00092 19.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGF83318.1 - 0.0012 18.3 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EGF83318.1 - 0.013 15.5 0.1 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_14 PF13173.6 EGF83318.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGF83318.1 - 0.086 12.7 0.7 0.17 11.8 0.7 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGF83318.1 - 0.19 12.1 0.0 0.24 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Acetyltransf_10 PF13673.7 EGF83319.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EGF83320.1 - 1.2e-37 129.7 94.5 2.6e-31 108.8 56.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SHE3 PF17078.5 EGF83321.1 - 0.0043 16.8 13.6 0.0043 16.8 13.6 4.5 1 1 3 4 4 4 1 SWI5-dependent HO expression protein 3 Fn3_assoc PF13287.6 EGF83321.1 - 0.096 12.9 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Fn3 associated WD40 PF00400.32 EGF83322.1 - 7.7e-05 23.4 10.9 0.19 12.7 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83322.1 - 0.0062 16.8 0.0 0.62 10.4 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 EGF83323.1 - 8.4e-56 185.9 5.1 2.3e-23 81.9 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 EGF83323.1 - 0.097 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fuseless Inositol_P PF00459.25 EGF83324.1 - 2.8e-57 194.3 0.0 3.1e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF647 PF04884.14 EGF83325.1 - 3.9e-43 147.8 3.5 5.5e-43 147.3 3.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis M16C_assoc PF08367.11 EGF83326.1 - 2.3e-59 200.5 0.0 3.6e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGF83326.1 - 8.3e-25 87.9 0.0 1.9e-18 67.1 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGF83326.1 - 0.0014 18.6 0.0 0.0064 16.5 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Calreticulin PF00262.18 EGF83327.1 - 1.6e-161 537.3 5.9 2.2e-161 536.8 5.9 1.2 1 0 0 1 1 1 1 Calreticulin family FAM176 PF14851.6 EGF83327.1 - 0.02 14.6 1.0 0.059 13.0 1.0 1.7 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 EGF83327.1 - 0.036 13.8 0.3 0.059 13.1 0.3 1.3 1 0 0 1 1 1 0 Connexin FHIPEP PF00771.20 EGF83327.1 - 0.052 12.0 0.1 0.077 11.5 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family Conotoxin PF02950.17 EGF83327.1 - 0.078 14.0 0.4 0.28 12.2 0.0 2.0 2 0 0 2 2 2 0 Conotoxin Folate_carrier PF01770.18 EGF83327.1 - 0.24 10.1 0.2 0.34 9.6 0.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier TRAP_alpha PF03896.16 EGF83327.1 - 0.28 10.3 2.6 0.52 9.5 2.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Adeno_terminal PF02459.15 EGF83327.1 - 1.4 7.2 4.4 2 6.7 4.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein G0-G1_switch_2 PF15103.6 EGF83327.1 - 2.3 8.7 7.3 0.22 12.0 0.9 2.3 3 0 0 3 3 3 0 G0/G1 switch protein 2 Cys_Met_Meta_PP PF01053.20 EGF83328.1 - 8e-71 238.6 0.0 2.2e-70 237.1 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGF83328.1 - 0.082 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II WD40 PF00400.32 EGF83329.1 - 0.022 15.6 7.8 23 6.1 1.2 4.9 4 1 0 4 4 4 0 WD domain, G-beta repeat RNA_pol_Rpa2_4 PF06883.12 EGF83329.1 - 0.19 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain Sigma_1s PF02454.16 EGF83329.1 - 6.2 6.8 8.9 0.95 9.5 1.3 2.6 2 0 0 2 2 2 0 Sigma 1s protein RabGAP-TBC PF00566.18 EGF83330.1 - 3.1e-38 131.6 0.3 4.4e-38 131.1 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Beach PF02138.18 EGF83331.1 - 4.9e-123 409.9 2.0 2.8e-122 407.4 0.0 2.9 3 0 0 3 3 3 1 Beige/BEACH domain PH_BEACH PF14844.6 EGF83331.1 - 1.9e-14 53.6 0.0 6e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EGF83331.1 - 5e-12 46.1 11.4 0.086 13.7 2.3 6.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Laminin_G_3 PF13385.6 EGF83331.1 - 7.6e-11 42.4 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 EGF83331.1 - 2.7e-07 30.1 4.2 2.7e-07 30.1 4.2 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF4704) FYVE PF01363.21 EGF83331.1 - 6.7e-05 22.9 14.0 6.7e-05 22.9 14.0 2.8 2 0 0 2 2 2 1 FYVE zinc finger DUF4800 PF16057.5 EGF83331.1 - 0.0022 17.3 6.8 0.0022 17.3 6.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) Lon_C PF05362.13 EGF83332.1 - 5.4e-71 238.4 0.0 1.3e-70 237.1 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EGF83332.1 - 8.1e-32 110.8 2.1 8.1e-32 110.8 2.1 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EGF83332.1 - 1.9e-22 80.1 0.0 6.1e-22 78.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGF83332.1 - 6.9e-07 29.3 0.0 2.3e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGF83332.1 - 2.9e-05 23.9 0.1 0.00034 20.4 0.1 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 EGF83332.1 - 0.00016 20.7 0.0 0.00034 19.6 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 EGF83332.1 - 0.00017 21.9 0.1 0.0033 17.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain ChlI PF13541.6 EGF83332.1 - 0.00019 21.3 0.2 0.00095 19.0 0.0 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EGF83332.1 - 0.0007 19.8 4.6 0.001 19.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EGF83332.1 - 0.0023 18.5 0.1 0.031 14.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGF83332.1 - 0.0051 17.2 0.1 0.06 13.7 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EGF83332.1 - 0.034 14.3 0.1 0.12 12.6 0.1 1.9 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EGF83332.1 - 0.039 14.1 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 EGF83332.1 - 0.043 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EGF83332.1 - 0.049 13.7 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF83332.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGF83332.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGF83332.1 - 0.14 12.4 0.1 20 5.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 EGF83332.1 - 0.17 11.8 1.5 4.7 7.1 0.1 3.0 2 1 1 3 3 3 0 NTPase ABC_tran PF00005.27 EGF83332.1 - 2.8 8.5 5.4 0.57 10.7 0.1 2.5 3 0 0 3 3 2 0 ABC transporter TIP49 PF06068.13 EGF83332.1 - 3.2 6.9 7.5 0.32 10.1 0.2 2.7 3 1 0 3 3 3 0 TIP49 P-loop domain WD40 PF00400.32 EGF83333.1 - 9.7e-07 29.4 5.9 7.2e-05 23.5 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.32 EGF83334.1 - 9e-14 51.7 3.8 1.3e-06 29.0 0.2 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83334.1 - 0.00026 21.2 0.0 0.52 10.6 0.1 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2703 PF10865.8 EGF83335.1 - 0.0029 17.8 0.1 0.0032 17.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2703) RHSP PF07999.11 EGF83337.1 - 0.00047 19.1 0.6 0.0022 16.9 0.6 1.8 1 1 0 1 1 1 1 Retrotransposon hot spot protein Trypan_PARP PF05887.11 EGF83337.1 - 0.59 10.1 2.9 1.2 9.1 2.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2703 PF10865.8 EGF83338.1 - 0.02 15.1 0.1 0.041 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DHHC PF01529.20 EGF83340.1 - 5.1e-33 114.0 7.6 6.1e-33 113.8 7.6 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase QueC PF06508.13 EGF83340.1 - 8.2 5.9 6.0 13 5.2 6.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Mito_carr PF00153.27 EGF83341.1 - 1.5e-56 188.3 3.6 4.1e-22 77.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rgp1 PF08737.10 EGF83342.1 - 1.4e-75 255.1 14.3 8.7e-41 140.4 0.3 3.0 2 2 1 3 3 3 2 Rgp1 Arrestin_C PF02752.22 EGF83342.1 - 0.00014 22.3 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Histone PF00125.24 EGF83343.1 - 7.1e-22 78.2 0.7 9.4e-22 77.8 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF83343.1 - 1.8e-06 28.1 1.1 6.8e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGF83343.1 - 0.00069 20.1 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EGF83343.1 - 0.0027 17.8 0.4 0.0036 17.4 0.4 1.3 1 0 0 1 1 1 1 YscO-like protein TFIIF_alpha PF05793.12 EGF83344.1 - 5.9e-19 68.1 38.4 1.3e-13 50.4 26.2 3.2 2 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dimerisation PF08100.11 EGF83344.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Pet100 PF09803.9 EGF83344.1 - 2.4 8.7 6.9 27 5.4 1.5 3.8 3 1 0 3 3 3 0 Pet100 ABC2_membrane PF01061.24 EGF83345.1 - 1e-43 149.3 12.4 1e-43 149.3 12.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGF83345.1 - 2.1e-28 99.5 0.0 3.6e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGF83345.1 - 4.7e-05 23.4 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGF83345.1 - 0.0022 18.1 0.1 0.0046 17.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EGF83345.1 - 0.0034 17.6 0.3 0.0073 16.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF83345.1 - 0.0044 17.4 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGF83345.1 - 0.007 16.1 0.5 0.017 14.8 0.5 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGF83345.1 - 0.04 14.0 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Dynamin family ABC2_membrane_3 PF12698.7 EGF83345.1 - 0.068 12.3 18.1 0.018 14.1 12.8 2.1 1 1 0 2 2 2 0 ABC-2 family transporter protein ArAE_2_N PF10337.9 EGF83345.1 - 0.076 12.0 0.5 0.16 10.9 0.5 1.5 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal AAA_21 PF13304.6 EGF83345.1 - 0.079 12.8 0.4 14 5.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EGF83345.1 - 0.13 12.2 0.5 0.29 11.0 0.5 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EGF83345.1 - 0.14 11.8 0.5 0.27 10.8 0.5 1.4 1 0 0 1 1 1 0 AAA domain TMEM95 PF15203.6 EGF83345.1 - 0.18 11.4 0.1 0.44 10.2 0.1 1.6 1 0 0 1 1 1 0 TMEM95 family NTPase_1 PF03266.15 EGF83345.1 - 0.26 11.2 2.0 11 5.9 0.1 2.4 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.9 EGF83345.1 - 0.33 9.7 1.6 0.61 8.8 1.6 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PBP1_TM PF14812.6 EGF83346.1 - 0.016 15.6 2.1 0.042 14.2 2.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S21 PF01165.20 EGF83347.1 - 2.7e-08 33.4 1.9 2.7e-08 33.4 1.9 2.0 2 1 0 2 2 2 1 Ribosomal protein S21 cNMP_binding PF00027.29 EGF83348.1 - 1e-07 31.9 0.0 3.2e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Mga PF05043.13 EGF83348.1 - 0.1 13.2 0.0 0.58 10.8 0.0 2.1 2 1 1 3 3 3 0 Mga helix-turn-helix domain AFG1_ATPase PF03969.16 EGF83349.1 - 7e-108 360.7 0.1 3.2e-102 342.1 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EGF83349.1 - 3.9e-05 24.1 0.1 0.023 15.1 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.18 EGF83349.1 - 0.00027 20.8 0.2 0.022 14.6 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_30 PF13604.6 EGF83349.1 - 0.0023 17.7 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGF83349.1 - 0.0056 16.9 0.2 0.057 13.7 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA PF00004.29 EGF83349.1 - 0.071 13.5 0.2 0.84 10.1 0.0 2.8 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGF83349.1 - 0.091 12.2 0.0 0.39 10.1 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EGF83349.1 - 0.12 12.1 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 EGF83349.1 - 0.12 12.1 0.1 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGF83349.1 - 0.15 12.5 0.0 0.86 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EGF83349.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI XdhC_CoxI PF02625.16 EGF83350.1 - 0.021 15.0 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 XdhC and CoxI family PP2C PF00481.21 EGF83351.1 - 3.6e-69 233.3 0.1 4.2e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.31 EGF83353.1 - 2.4e-22 78.9 0.9 3.7e-07 30.2 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF83353.1 - 8.7e-14 51.5 2.9 6.6e-05 23.1 0.2 4.0 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGF83353.1 - 4e-10 39.4 2.7 0.01 15.7 0.0 4.3 3 0 0 3 3 3 3 Myb DNA-binding like Osmo_CC PF08946.10 EGF83353.1 - 0.083 13.1 2.5 0.23 11.8 2.5 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil GPS2_interact PF15784.5 EGF83353.1 - 1.4 9.4 5.0 0.93 10.0 1.6 2.6 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Tim17 PF02466.19 EGF83354.1 - 7.5e-30 103.6 4.1 1e-29 103.1 4.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EGF83354.1 - 0.014 15.7 3.6 0.46 10.9 0.2 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Sec23_trunk PF04811.15 EGF83355.1 - 1.1e-73 247.8 0.0 1.6e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGF83355.1 - 2.7e-28 98.5 0.5 5.3e-28 97.6 0.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGF83355.1 - 4.8e-25 87.4 0.1 9.3e-25 86.4 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGF83355.1 - 1.1e-17 63.7 8.5 2.6e-17 62.6 8.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGF83355.1 - 1.5e-10 40.8 0.0 4.8e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Gelsolin repeat RA PF00788.23 EGF83356.1 - 7.5e-18 65.0 0.0 2.9e-08 34.2 0.0 3.1 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain Fib_alpha PF08702.10 EGF83356.1 - 2.7 8.2 7.5 2.9 8.1 1.8 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40_4 PF16300.5 EGF83357.1 - 7.4e-31 105.8 0.5 4.2e-14 52.1 0.1 2.7 3 0 0 3 3 3 2 Type of WD40 repeat DUF1899 PF08953.11 EGF83357.1 - 1.5e-11 44.0 1.3 1.5e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 EGF83357.1 - 7.6e-08 32.6 0.5 0.24 11.7 0.0 5.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF83357.1 - 9.9e-05 23.0 4.5 4.4 8.4 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat I_LWEQ PF01608.17 EGF83358.1 - 5.9e-43 146.7 127.0 7.7e-43 146.4 6.6 16.1 8 3 8 18 18 18 8 I/LWEQ domain FERM_M PF00373.18 EGF83358.1 - 1.8e-25 89.6 0.1 8.2e-25 87.5 0.1 2.3 1 0 0 1 1 1 1 FERM central domain Talin_middle PF09141.10 EGF83358.1 - 7e-23 81.4 6.4 7e-23 81.4 6.4 13.4 10 4 2 13 13 13 5 Talin, middle domain FERM_f0 PF16511.5 EGF83358.1 - 2.6e-22 78.9 0.7 1.2e-20 73.5 0.1 3.7 3 1 0 3 3 3 1 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 EGF83358.1 - 8.5e-14 51.3 0.1 6.4e-13 48.4 0.0 2.7 2 0 0 2 2 2 1 FERM N-terminal domain IRS PF02174.17 EGF83358.1 - 0.0004 20.2 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 PTB domain (IRS-1 type) RA PF00788.23 EGF83358.1 - 0.0019 18.8 0.0 0.059 14.0 0.0 2.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain VBS PF08913.10 EGF83358.1 - 0.014 15.8 0.2 0.014 15.8 0.2 10.7 11 1 0 11 11 11 0 Vinculin Binding Site ACBP PF00887.19 EGF83358.1 - 0.095 12.9 0.0 0.43 10.8 0.0 2.2 1 0 0 1 1 1 0 Acyl CoA binding protein SHMT PF00464.19 EGF83359.1 - 1.9e-202 672.1 0.0 2.3e-202 671.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase ATG16 PF08614.11 EGF83360.1 - 2.6e-49 168.2 23.1 3.9e-49 167.6 23.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 EGF83360.1 - 1.6e-32 111.0 24.8 1.5e-05 25.7 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83360.1 - 2.1e-10 40.8 1.2 0.036 14.4 0.0 5.5 3 2 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF83360.1 - 0.00014 21.9 0.1 3.6 7.4 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGF83360.1 - 0.00056 19.0 3.9 0.0059 15.6 0.1 3.7 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGF83360.1 - 0.00061 19.2 0.4 0.04 13.3 0.1 2.8 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 EGF83360.1 - 0.0011 17.7 2.8 0.51 8.9 0.1 3.9 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Utp12 PF04003.12 EGF83360.1 - 0.2 12.0 3.2 15 6.0 0.3 2.9 2 1 0 2 2 2 0 Dip2/Utp12 Family FAM76 PF16046.5 EGF83360.1 - 1.8 7.8 18.1 3.6 6.9 1.2 2.3 1 1 1 2 2 2 0 FAM76 protein FemAB PF02388.16 EGF83360.1 - 3 6.6 8.8 2.6 6.8 1.0 2.7 1 1 1 3 3 3 0 FemAB family Forkhead PF00250.18 EGF83361.1 - 7.5e-32 109.4 0.2 1.6e-31 108.4 0.2 1.6 1 0 0 1 1 1 1 Forkhead domain Sigma54_activat PF00158.26 EGF83361.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Linker_histone PF00538.19 EGF83361.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family HNH_2 PF13391.6 EGF83363.1 - 2e-05 24.6 0.0 7.4e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EGF83363.1 - 0.19 11.9 2.4 1.4 9.2 2.4 2.4 1 1 0 1 1 1 0 HNH endonuclease MAM33 PF02330.16 EGF83364.1 - 1.1e-53 182.4 4.1 1.4e-53 182.0 4.1 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Toprim_N PF08275.11 EGF83364.1 - 0.12 12.4 0.3 2.7 8.0 0.1 2.2 2 0 0 2 2 2 0 DNA primase catalytic core, N-terminal domain SHMT PF00464.19 EGF83365.1 - 2.9e-174 579.4 0.0 3.3e-174 579.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGF83365.1 - 0.0048 16.2 0.0 0.015 14.6 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGF83365.1 - 0.015 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGF83365.1 - 0.042 13.0 0.0 0.096 11.8 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II DEAD PF00270.29 EGF83366.1 - 1.5e-48 164.9 0.6 4.5e-48 163.3 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF83366.1 - 2.5e-31 108.3 0.1 3.5e-30 104.6 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF83366.1 - 7.9e-06 26.0 0.0 2.4e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGF83366.1 - 0.048 13.9 0.2 0.17 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain GST_N_3 PF13417.6 EGF83366.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ERCC3_RAD25_C PF16203.5 EGF83366.1 - 0.077 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Phage_DsbA PF11126.8 EGF83367.1 - 0.079 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA zf-CHY PF05495.12 EGF83367.1 - 0.11 12.9 1.7 0.21 12.1 1.7 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.6 EGF83367.1 - 0.18 11.7 1.5 0.35 10.8 1.5 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Kinesin PF00225.23 EGF83368.1 - 1.8e-91 306.5 4.4 1.8e-91 306.5 4.4 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGF83368.1 - 5.6e-29 101.0 0.2 5.6e-29 101.0 0.2 2.1 3 0 0 3 3 3 1 Microtubule binding HHH_3 PF12836.7 EGF83368.1 - 6.9e-06 26.2 0.0 2.3e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_6 PF14579.6 EGF83368.1 - 0.0093 16.2 0.0 0.034 14.4 0.0 1.9 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 EGF83368.1 - 0.025 14.5 0.0 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif AAA_22 PF13401.6 EGF83368.1 - 0.1 12.9 0.9 0.4 11.0 0.9 2.0 1 1 0 1 1 1 0 AAA domain UPF0767 PF15990.5 EGF83368.1 - 0.14 12.4 0.4 0.72 10.0 0.4 2.2 1 0 0 1 1 1 0 UPF0767 family PCI PF01399.27 EGF83369.1 - 5.4e-10 39.7 0.8 1.4e-09 38.4 0.8 1.7 1 0 0 1 1 1 1 PCI domain AMP-binding PF00501.28 EGF83371.1 - 3.2e-108 362.0 0.0 4.2e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGF83371.1 - 6.3e-05 23.9 0.0 0.00034 21.5 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phosducin PF02114.16 EGF83372.1 - 8.7e-30 103.5 0.0 1.2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGF83372.1 - 0.018 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin XPG_N PF00752.17 EGF83373.1 - 3.2e-35 120.6 0.0 5.8e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGF83373.1 - 4.3e-31 107.1 0.0 8.4e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EGF83373.1 - 1.9e-05 25.1 0.0 4.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 EGF83373.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain Fe_dep_repr_C PF02742.15 EGF83373.1 - 0.014 15.5 0.0 0.42 10.7 0.0 2.7 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Exo_endo_phos PF03372.23 EGF83374.1 - 4.3e-19 69.0 1.1 4.8e-18 65.5 1.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EGF83374.1 - 7.6e-11 41.6 26.5 5.2e-07 29.3 7.0 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGF83374.1 - 3.1e-09 36.9 8.0 5.9e-05 23.4 1.9 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF83374.1 - 0.82 10.5 8.9 26 5.9 0.2 5.0 3 2 1 4 4 4 0 Leucine Rich Repeat Glycos_transf_1 PF00534.20 EGF83375.1 - 7.2e-32 110.3 0.0 2.6e-31 108.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGF83375.1 - 1.5e-17 64.1 0.0 2.2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGF83375.1 - 2.1e-13 50.8 0.0 3.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGF83375.1 - 9.3e-07 29.4 0.0 1.7e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGF83375.1 - 0.00027 21.3 0.0 0.00067 20.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EGF83375.1 - 0.017 15.2 1.1 44 4.0 0.0 4.0 3 1 0 4 4 4 0 ALG11 mannosyltransferase N-terminus Glyco_transf_20 PF00982.21 EGF83375.1 - 0.074 11.7 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 20 PK PF00224.21 EGF83376.1 - 2e-100 336.1 7.0 2.7e-100 335.7 7.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGF83376.1 - 3.9e-20 72.2 0.8 3.9e-20 72.2 0.8 2.5 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGF83376.1 - 0.075 12.2 1.0 0.17 11.0 0.2 1.9 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Solute_trans_a PF03619.16 EGF83377.1 - 2e-96 322.6 17.6 2.3e-96 322.4 17.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 EGF83377.1 - 0.016 15.4 0.4 0.016 15.4 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) DUF2273 PF10031.9 EGF83377.1 - 0.062 13.3 0.1 0.062 13.3 0.1 2.3 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF373 PF04123.13 EGF83377.1 - 1.1 8.6 10.4 0.58 9.5 2.8 2.4 1 1 1 3 3 3 0 Domain of unknown function (DUF373) Atx10homo_assoc PF09759.9 EGF83378.1 - 5.5e-36 122.6 2.9 3.5e-33 113.6 0.3 4.0 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Atg14 PF10186.9 EGF83378.1 - 0.042 12.9 0.3 0.042 12.9 0.3 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRCA-2_OB1 PF09103.10 EGF83379.1 - 8.3e-28 96.8 0.0 1.7e-26 92.6 0.0 2.8 2 1 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EGF83379.1 - 1.9e-15 57.1 0.5 4.5e-12 46.0 0.4 2.5 1 1 1 2 2 2 2 BRCA2, helical Tower PF09121.10 EGF83379.1 - 0.065 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Tower Picorna_P3A PF06363.11 EGF83381.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.6 2 0 0 2 2 2 0 Picornaviridae P3A protein ABC_membrane PF00664.23 EGF83382.1 - 3.8e-59 200.6 40.3 2.5e-37 129.0 9.6 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF83382.1 - 7.8e-46 156.0 0.0 1.9e-26 93.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF83382.1 - 8.8e-09 35.1 0.0 0.022 14.2 0.0 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF83382.1 - 4e-06 26.9 0.5 0.69 9.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGF83382.1 - 7.9e-06 26.5 0.0 0.0043 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGF83382.1 - 8.8e-05 22.5 0.1 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGF83382.1 - 0.00011 22.7 0.3 0.34 11.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EGF83382.1 - 0.00046 19.8 0.1 0.42 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGF83382.1 - 0.0018 18.5 1.3 1.2 9.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGF83382.1 - 0.0026 17.5 0.3 3.5 7.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGF83382.1 - 0.0029 17.3 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 EGF83382.1 - 0.004 16.9 0.1 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGF83382.1 - 0.011 14.8 0.1 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EGF83382.1 - 0.012 15.7 0.2 2 8.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 EGF83382.1 - 0.02 14.8 0.0 0.27 11.1 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 EGF83382.1 - 0.097 12.2 0.1 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EGF83382.1 - 0.099 12.0 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EGF83382.1 - 0.11 11.8 0.2 13 5.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EGF83382.1 - 0.19 11.2 0.3 12 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EGF83382.1 - 0.2 11.3 0.3 22 4.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGF83382.1 - 0.53 10.3 5.5 2.1 8.4 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain PS_Dcarbxylase PF02666.15 EGF83384.1 - 2e-63 213.5 0.0 2.4e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase COPI_C PF06957.11 EGF83385.1 - 2.3e-135 451.5 0.0 3.3e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 EGF83385.1 - 9.7e-132 440.1 0.2 1.6e-131 439.5 0.2 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EGF83385.1 - 2.2e-41 139.0 16.5 2.5e-09 37.6 0.7 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83385.1 - 6.5e-13 48.8 0.5 9.4e-06 25.8 0.0 5.5 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF83385.1 - 0.019 13.6 2.5 0.42 9.2 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 LisH PF08513.11 EGF83385.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 LisH DUF2043 PF09740.9 EGF83386.1 - 1.1e-30 106.4 0.0 3.1e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) RICH PF05062.12 EGF83386.1 - 8.3 6.8 9.9 0.44 10.9 3.2 2.2 2 0 0 2 2 2 0 RICH domain Alpha-2-MRAP_C PF06401.11 EGF83387.1 - 0.016 15.2 13.6 0.023 14.7 0.9 3.4 3 0 0 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain Cep57_MT_bd PF06657.13 EGF83387.1 - 0.085 13.3 11.7 0.095 13.2 0.6 4.1 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 EGF83387.1 - 0.55 9.5 9.2 0.28 10.5 4.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 EGF83387.1 - 0.97 9.6 12.1 1.1 9.4 0.9 4.3 4 0 0 4 4 4 0 bZIP transcription factor DivIC PF04977.15 EGF83387.1 - 1.1 9.1 5.1 0.98 9.2 1.2 2.9 2 0 0 2 2 2 0 Septum formation initiator CtIP_N PF10482.9 EGF83387.1 - 5.3 7.1 10.2 5.2 7.1 0.0 4.3 4 2 0 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain UPF0449 PF15136.6 EGF83387.1 - 5.9 7.4 7.7 1.8 9.1 1.3 3.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 SH3_9 PF14604.6 EGF83389.1 - 3.8e-09 36.3 0.1 5.6e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF83389.1 - 6.6e-09 35.3 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGF83389.1 - 2.2e-06 27.3 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Carboxyl_trans PF01039.22 EGF83390.1 - 1.5e-153 512.1 0.0 1.7e-153 511.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGF83390.1 - 0.00014 21.5 0.1 0.065 12.7 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) NAD_binding_1 PF00175.21 EGF83391.1 - 7.1e-30 103.9 0.0 1.1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGF83391.1 - 3.6e-20 72.1 0.0 6.9e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGF83391.1 - 1.3e-05 25.3 0.0 4.9e-05 23.5 0.0 1.8 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DSS1_SEM1 PF05160.13 EGF83392.1 - 5.7e-14 51.9 23.1 6.6e-14 51.7 23.1 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 EGF83392.1 - 0.0081 16.0 2.3 0.0087 15.9 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) G-gamma PF00631.22 EGF83393.1 - 9.3e-23 80.0 0.0 1e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain PX PF00787.24 EGF83394.1 - 1.4e-17 63.7 0.9 3.7e-17 62.3 0.9 1.7 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EGF83394.1 - 0.0012 18.5 0.1 0.0066 16.1 0.1 2.1 1 1 0 1 1 1 1 Variant SH3 domain BAR_3_WASP_bdg PF10456.9 EGF83394.1 - 0.0082 15.6 0.3 0.67 9.4 0.0 2.5 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein DUF3507 PF12015.8 EGF83394.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) SH3_4 PF06347.13 EGF83394.1 - 0.066 13.0 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial SH3 domain Thioredoxin PF00085.20 EGF83395.1 - 1.4e-05 25.0 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGF83395.1 - 0.057 13.9 0.1 0.092 13.2 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1694 PF07997.11 EGF83395.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) OST3_OST6 PF04756.13 EGF83395.1 - 0.084 12.2 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Mid2 PF04478.12 EGF83396.1 - 2.1e-05 24.4 4.1 4.5e-05 23.3 4.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EGF83396.1 - 6.9e-05 22.8 1.7 6.9e-05 22.8 1.7 1.9 2 0 0 2 2 2 1 TMEM154 protein family Stevor PF17410.2 EGF83396.1 - 0.001 18.7 1.9 0.0019 17.8 1.9 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 EGF83396.1 - 0.0046 16.9 0.2 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Rifin PTP_tm PF18861.1 EGF83396.1 - 0.0048 16.9 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF456 PF04306.13 EGF83396.1 - 0.015 15.6 0.3 0.035 14.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF456) TMEM65 PF10507.9 EGF83396.1 - 0.027 14.4 2.6 0.07 13.1 2.6 1.7 1 0 0 1 1 1 0 Transmembrane protein 65 DUF2231 PF09990.9 EGF83396.1 - 0.086 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) TraL PF07178.11 EGF83396.1 - 0.1 13.1 0.3 0.31 11.5 0.3 1.8 1 0 0 1 1 1 0 TraL protein Amnionless PF14828.6 EGF83396.1 - 0.13 11.0 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 Amnionless DUF2085 PF09858.9 EGF83396.1 - 0.14 12.7 3.8 0.86 10.1 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) Saf_2TM PF18303.1 EGF83396.1 - 0.17 11.5 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF5305 PF17231.2 EGF83396.1 - 0.24 10.8 2.0 0.41 10.0 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) AJAP1_PANP_C PF15298.6 EGF83396.1 - 6.6 6.9 17.6 0.25 11.5 10.6 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF4834 PF16118.5 EGF83397.1 - 0.063 14.2 1.1 0.4 11.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Borrelia_orfA PF02414.15 EGF83397.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.1 2 0 0 2 2 2 0 Borrelia ORF-A Zip PF02535.22 EGF83397.1 - 0.26 10.4 5.3 0.5 9.5 5.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 EGF83397.1 - 1.8 7.8 3.7 3.2 7.0 3.7 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein V_ATPase_I PF01496.19 EGF83397.1 - 6.9 4.5 8.6 1.4 6.7 2.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAP206 PF12018.8 EGF83398.1 - 4e-72 243.0 1.4 5e-72 242.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function Herpes_LAMP2 PF06126.11 EGF83398.1 - 0.038 12.6 2.4 0.059 12.0 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 F_actin_bind PF08919.10 EGF83398.1 - 0.33 11.0 6.5 1 9.5 0.0 3.6 4 0 0 4 4 4 0 F-actin binding Cor1 PF04803.12 EGF83398.1 - 7.7 6.7 9.3 1.3 9.2 3.0 2.8 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF1764 PF08576.10 EGF83399.1 - 1.7e-08 35.3 4.9 1.4e-06 29.1 4.9 2.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Glyco_hydro_47 PF01532.20 EGF83400.1 - 2.6e-57 194.8 2.7 1.1e-36 126.7 0.6 2.9 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 tRNA-synt_1b PF00579.25 EGF83402.1 - 1.4e-64 218.2 0.0 2.3e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) M11L PF11099.8 EGF83402.1 - 0.027 14.7 0.2 0.088 13.1 0.1 1.8 2 0 0 2 2 2 0 Apoptosis regulator M11L like FancD2 PF14631.6 EGF83404.1 - 8.1 3.7 14.1 8.4 3.6 14.1 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease HTH_23 PF13384.6 EGF83405.1 - 4.4e-09 35.9 0.9 8e-05 22.3 0.1 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_7 PF02796.15 EGF83405.1 - 5.7e-09 35.9 1.0 0.0016 18.5 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 EGF83405.1 - 1.1e-07 32.3 3.1 2.4e-05 24.8 0.4 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EGF83405.1 - 1.2e-07 31.7 0.4 0.00096 19.2 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_22 PF13309.6 EGF83405.1 - 1e-05 25.5 0.1 0.067 13.3 0.0 2.7 2 0 0 2 2 2 2 HTH domain HTH_17 PF12728.7 EGF83405.1 - 1.5e-05 25.1 1.0 0.27 11.5 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 EGF83405.1 - 4.6e-05 23.6 5.2 0.014 15.5 0.3 2.6 3 0 0 3 3 2 2 Helix-turn-helix of insertion element transposase HTH_Tnp_IS630 PF01710.16 EGF83405.1 - 8.1e-05 22.7 1.1 0.37 10.8 0.1 2.8 3 0 0 3 3 3 2 Transposase HTH_29 PF13551.6 EGF83405.1 - 0.00035 20.5 1.2 0.42 10.7 0.0 2.8 3 0 0 3 3 3 2 Winged helix-turn helix HTH_33 PF13592.6 EGF83405.1 - 0.0004 20.0 0.3 0.0004 20.0 0.3 3.4 4 0 0 4 4 4 1 Winged helix-turn helix HTH_11 PF08279.12 EGF83405.1 - 0.0012 18.8 0.2 1.8 8.6 0.1 2.5 2 0 0 2 2 2 2 HTH domain HTH_Tnp_1 PF01527.20 EGF83405.1 - 0.003 17.8 2.0 0.003 17.8 2.0 2.1 2 0 0 2 2 2 1 Transposase Terminase_5 PF06056.12 EGF83405.1 - 0.0046 16.8 1.0 0.45 10.5 0.2 2.5 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) DUF1804 PF08822.11 EGF83405.1 - 0.016 15.2 2.0 0.028 14.4 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) HTH_psq PF05225.16 EGF83405.1 - 0.02 14.6 2.5 0.039 13.7 0.2 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_4 PF13613.6 EGF83405.1 - 0.021 14.5 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 EGF83405.1 - 0.037 13.8 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 EGF83405.1 - 0.053 13.8 0.3 0.12 12.6 0.1 1.8 2 0 0 2 2 1 0 Transposase DUF4065 PF13274.6 EGF83405.1 - 0.066 14.1 0.1 0.15 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) HTH_DeoR PF08220.12 EGF83405.1 - 0.071 12.9 0.7 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain TetR_N PF00440.23 EGF83405.1 - 0.087 12.6 0.3 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family LysM PF01476.20 EGF83405.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 LysM domain HTH_36 PF13730.6 EGF83405.1 - 0.13 12.2 0.1 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Mga PF05043.13 EGF83405.1 - 0.13 12.8 1.2 1.9 9.1 0.2 2.5 2 1 1 3 3 3 0 Mga helix-turn-helix domain SCIMP PF15050.6 EGF83406.1 - 0.0021 18.5 0.0 0.0033 17.9 0.0 1.2 1 0 0 1 1 1 1 SCIMP protein DUF4083 PF13314.6 EGF83406.1 - 0.017 15.0 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Beta-lactamase2 PF13354.6 EGF83406.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family KCH PF16944.5 EGF83407.1 - 6.1e-53 180.2 15.2 6.1e-53 180.2 15.2 2.2 2 1 0 2 2 2 1 Fungal potassium channel DUF4064 PF13273.6 EGF83407.1 - 0.046 14.0 2.0 6.5 7.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) GATA PF00320.27 EGF83408.1 - 7.7e-15 54.2 3.7 7.7e-15 54.2 3.7 2.5 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.7 EGF83408.1 - 0.027 14.5 7.6 1.3 9.1 2.6 2.7 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGF83408.1 - 2.9 8.1 4.7 6.2 7.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.18 EGF83408.1 - 3 7.9 11.4 0.52 10.4 0.2 3.1 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 EGF83408.1 - 7.5 6.2 9.7 0.98 9.0 0.8 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding TAXi_C PF14541.6 EGF83410.1 - 0.0056 16.5 0.0 0.045 13.5 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal ABC_tran PF00005.27 EGF83412.1 - 4.2e-27 95.3 0.0 7.1e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGF83412.1 - 0.002 18.1 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 EGF83412.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.19 EGF83412.1 - 0.0052 16.3 0.1 0.31 10.5 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EGF83412.1 - 0.015 14.9 0.6 0.36 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGF83412.1 - 0.016 14.9 0.2 0.059 13.1 0.2 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGF83412.1 - 0.029 14.9 0.1 0.051 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGF83412.1 - 0.031 14.7 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EGF83412.1 - 0.034 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGF83412.1 - 0.034 13.9 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGF83412.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGF83412.1 - 0.067 13.3 0.6 0.16 12.0 0.2 1.7 1 1 1 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EGF83412.1 - 0.073 13.3 0.2 0.22 11.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGF83412.1 - 0.079 13.4 0.3 0.64 10.5 0.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGF83412.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGF83412.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 EGF83412.1 - 0.2 11.4 0.1 0.6 9.8 0.1 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC2_membrane_3 PF12698.7 EGF83412.1 - 0.38 9.8 17.8 0.77 8.8 17.8 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein SET PF00856.28 EGF83413.1 - 1.5e-05 25.5 0.0 0.00039 20.8 0.0 2.1 1 1 0 1 1 1 1 SET domain Smg4_UPF3 PF03467.15 EGF83414.1 - 1.6e-44 152.0 0.0 1.6e-44 152.0 0.0 3.1 2 1 1 3 3 3 1 Smg-4/UPF3 family Vma12 PF11712.8 EGF83414.1 - 4.3 7.4 7.5 0.82 9.7 3.4 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_hydro_81 PF03639.13 EGF83415.1 - 0.035 13.3 0.7 0.094 11.9 0.2 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 81 N-terminal domain DnaJ PF00226.31 EGF83416.1 - 2.4e-12 46.8 3.2 5e-12 45.8 3.2 1.6 1 0 0 1 1 1 1 DnaJ domain PAN_4 PF14295.6 EGF83417.1 - 4.4e-06 26.5 0.6 1e-05 25.4 0.6 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EGF83417.1 - 2.1e-05 24.4 0.3 5e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 EGF83417.1 - 2.9e-05 23.7 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EGF83417.1 - 0.037 13.4 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 COX6B PF02297.17 EGF83418.1 - 2.9e-18 65.9 7.7 3.3e-18 65.7 7.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EGF83418.1 - 0.016 15.2 3.7 0.03 14.3 3.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EGF83418.1 - 0.036 14.0 0.2 0.056 13.4 0.2 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain DUF1929 PF09118.11 EGF83419.1 - 1.4e-22 79.7 0.4 3.1e-22 78.7 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 EGF83419.1 - 1.6e-21 76.6 0.0 1.4e-20 73.6 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 EGF83419.1 - 0.23 11.8 3.5 9.4 6.7 0.0 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF83419.1 - 3.3 8.2 8.2 58 4.2 0.1 4.7 4 2 1 5 5 5 0 Kelch motif DUF1929 PF09118.11 EGF83420.1 - 1.5e-24 86.1 0.2 3.7e-24 84.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 EGF83420.1 - 5.2e-21 74.9 0.5 1.9e-19 69.8 0.2 3.4 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 EGF83420.1 - 0.0043 17.3 11.8 0.14 12.5 0.1 5.6 5 1 1 6 6 6 1 Kelch motif Kelch_3 PF13415.6 EGF83420.1 - 0.013 15.8 1.3 0.05 13.9 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1929 PF09118.11 EGF83421.1 - 5.2e-23 81.2 0.2 1.3e-22 79.9 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 EGF83421.1 - 5.2e-21 75.0 0.1 2.3e-19 69.6 0.0 3.3 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 EGF83421.1 - 0.003 17.8 13.5 0.13 12.5 0.1 6.1 6 1 1 7 7 7 1 Kelch motif Kelch_3 PF13415.6 EGF83421.1 - 0.0058 16.9 0.2 0.049 13.9 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EGF83421.1 - 0.11 12.5 1.3 7.6 6.7 0.0 3.8 4 0 0 4 4 4 0 Kelch motif AAA PF00004.29 EGF83422.1 - 5.1e-43 146.7 0.0 8.7e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF83422.1 - 3.7e-08 33.0 0.0 8.5e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGF83422.1 - 1.8e-05 24.8 0.0 0.0002 21.4 0.2 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF83422.1 - 2e-05 25.0 1.2 0.0026 18.2 0.1 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGF83422.1 - 2.8e-05 24.4 0.3 0.0045 17.3 0.2 2.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGF83422.1 - 4.4e-05 23.3 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGF83422.1 - 7.3e-05 23.3 0.0 0.00019 22.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGF83422.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EGF83422.1 - 0.00082 19.5 0.0 0.0056 16.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGF83422.1 - 0.00091 19.4 0.0 0.0019 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGF83422.1 - 0.0012 18.3 0.3 0.0031 16.9 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGF83422.1 - 0.0017 18.2 0.0 0.038 13.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EGF83422.1 - 0.002 17.4 0.2 0.0036 16.5 0.1 1.5 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 EGF83422.1 - 0.0022 18.0 0.0 0.0062 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGF83422.1 - 0.0045 16.6 0.6 0.13 11.8 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGF83422.1 - 0.014 15.7 0.0 0.036 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGF83422.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EGF83422.1 - 0.019 14.1 0.0 0.056 12.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EGF83422.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TniB PF05621.11 EGF83422.1 - 0.025 14.0 0.0 1 8.8 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EGF83422.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 EGF83422.1 - 0.04 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hydin_ADK PF17213.3 EGF83422.1 - 0.041 14.2 0.1 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 EGF83422.1 - 0.048 13.4 0.2 0.12 12.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF83422.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 EGF83422.1 - 0.058 12.8 0.3 0.14 11.6 0.2 1.6 1 1 0 1 1 1 0 PhoH-like protein Bac_DnaA PF00308.18 EGF83422.1 - 0.069 13.0 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.12 EGF83422.1 - 0.086 12.7 0.1 0.3 11.0 0.1 1.9 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGF83422.1 - 0.12 12.9 0.1 0.74 10.3 0.1 2.3 1 1 1 2 2 2 0 ABC transporter AAA_30 PF13604.6 EGF83422.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGF83422.1 - 0.14 11.9 0.1 0.41 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain IPT PF01745.16 EGF83422.1 - 0.19 11.1 0.0 0.44 9.9 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase ATPase PF06745.13 EGF83422.1 - 0.2 11.0 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC DHHC PF01529.20 EGF83423.1 - 3.8e-14 52.9 3.3 3.8e-14 52.9 3.3 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Amido_AtzD_TrzD PF09663.10 EGF83423.1 - 0.13 11.2 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) DUF4709 PF15821.5 EGF83424.1 - 0.0013 19.0 1.3 0.0013 19.0 1.3 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4709) WD40 PF00400.32 EGF83425.1 - 2.6e-14 53.4 15.4 7.9e-05 23.4 0.1 8.5 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83425.1 - 4.6e-05 23.6 0.0 7.5 6.9 0.0 5.5 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF83425.1 - 0.056 12.4 0.4 8.9 5.2 0.0 3.6 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_B561 PF03188.16 EGF83426.1 - 1.6e-07 31.6 7.9 3.8e-07 30.3 7.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 EGF83426.1 - 2.9e-07 30.3 0.2 5.4e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EGF83426.1 - 0.00047 20.4 0.3 0.0011 19.2 0.3 1.6 1 0 0 1 1 1 1 DOMON domain Colicin_V PF02674.16 EGF83426.1 - 0.014 15.4 3.9 0.014 15.4 3.9 1.9 2 0 0 2 2 2 0 Colicin V production protein DUF4079 PF13301.6 EGF83426.1 - 0.025 14.7 5.1 0.041 14.0 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF373 PF04123.13 EGF83426.1 - 0.062 12.7 2.0 0.13 11.7 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MRVI1 PF05781.12 EGF83426.1 - 0.12 11.0 0.5 0.17 10.6 0.5 1.1 1 0 0 1 1 1 0 MRVI1 protein Vut_1 PF02592.15 EGF83426.1 - 0.15 12.4 7.8 0.36 11.1 7.5 1.8 1 1 1 2 2 2 0 Putative vitamin uptake transporter BPD_transp_1 PF00528.22 EGF83426.1 - 0.47 10.2 9.6 1.8 8.3 9.7 2.1 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component MpPF26 PF07666.11 EGF83426.1 - 0.58 10.3 6.9 1.1 9.3 6.9 1.5 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF2427 PF10348.9 EGF83426.1 - 0.8 9.5 9.7 0.43 10.4 6.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) CDH-cyt PF16010.5 EGF83427.1 - 7.5e-13 48.6 0.1 2.1e-12 47.1 0.1 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EGF83427.1 - 3e-08 33.9 12.4 3e-08 33.9 12.4 2.1 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EGF83427.1 - 1.9e-06 28.1 0.2 3.3e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 DOMON domain fn3_2 PF16893.5 EGF83428.1 - 6.5e-31 106.3 0.1 9.9e-31 105.7 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EGF83428.1 - 1.2e-23 82.8 0.1 2.1e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EGF83428.1 - 2.8e-16 59.2 0.0 5.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EGF83428.1 - 1.2e-11 44.8 0.0 9.5e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EGF83428.1 - 1.1e-08 35.1 0.0 6.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EGF83428.1 - 0.0038 17.5 0.1 0.015 15.6 0.0 2.0 2 1 0 2 2 2 1 Fibronectin type III domain BRCT_2 PF16589.5 EGF83428.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ELP6 PF09807.9 EGF83429.1 - 9.6e-24 84.2 6.5 3.8e-22 78.9 6.5 2.0 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 EGF83429.1 - 5.4e-08 32.7 1.5 7.5e-08 32.2 1.5 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF835 PF05763.12 EGF83429.1 - 0.00014 21.6 0.4 0.00022 21.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF835) ATPase PF06745.13 EGF83429.1 - 0.0033 16.8 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EGF83429.1 - 0.072 13.0 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ubiquitin PF00240.23 EGF83430.1 - 1.5e-15 56.7 0.1 1.8e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGF83430.1 - 2.7e-06 27.1 0.0 3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGF83430.1 - 0.017 15.6 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Ras PF00071.22 EGF83431.1 - 1.1e-45 155.2 0.1 8.9e-43 145.7 0.1 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGF83431.1 - 3.4e-33 114.4 0.0 1.2e-32 112.7 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF83431.1 - 4.1e-13 49.2 0.0 7.5e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF83431.1 - 9.5e-07 28.9 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF83431.1 - 3.7e-06 26.5 0.0 6.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGF83431.1 - 1.6e-05 24.5 0.0 0.00014 21.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGF83431.1 - 0.0012 18.6 0.0 0.0079 16.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGF83431.1 - 0.012 15.5 0.1 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EGF83431.1 - 0.026 14.8 0.1 0.27 11.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 EGF83431.1 - 0.044 13.1 0.1 0.088 12.1 0.1 1.5 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 EGF83431.1 - 0.061 13.7 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGF83431.1 - 0.097 11.9 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Septin ATPase PF06745.13 EGF83431.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC GAT PF03127.14 EGF83432.1 - 6.5e-09 36.0 2.3 2.9e-08 33.9 2.3 2.2 1 0 0 1 1 1 1 GAT domain LRR_6 PF13516.6 EGF83432.1 - 2.9e-08 33.1 12.0 0.0044 17.0 0.0 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 EGF83432.1 - 0.044 14.3 14.9 33 5.6 0.0 7.5 7 1 0 7 7 7 0 Leucine Rich Repeat Ank_2 PF12796.7 EGF83433.1 - 1.1e-05 25.9 3.3 0.19 12.3 0.3 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF83433.1 - 0.06 13.9 5.7 24 5.6 0.2 4.9 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF83433.1 - 0.088 13.4 2.9 86 4.2 0.0 4.7 5 0 0 5 5 5 0 Ankyrin repeat Med10 PF09748.9 EGF83434.1 - 3e-26 91.8 0.4 3.4e-26 91.6 0.4 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Sua5_yciO_yrdC PF01300.18 EGF83435.1 - 4.5e-53 179.4 0.0 6.1e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGF83435.1 - 2.8e-30 105.6 0.0 4.1e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding CENP-K PF11802.8 EGF83435.1 - 0.15 11.6 0.2 0.22 11.1 0.2 1.1 1 0 0 1 1 1 0 Centromere-associated protein K TMEM70 PF06979.12 EGF83436.1 - 0.3 11.5 1.9 0.5 10.8 1.9 1.4 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex adh_short PF00106.25 EGF83437.1 - 2.7e-23 82.4 0.9 1.4e-18 67.1 0.3 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGF83437.1 - 5.6e-13 49.0 0.4 3.3e-06 26.8 0.7 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Helicase_RecD PF05127.14 EGF83437.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase ATP-synt_DE PF00401.20 EGF83437.1 - 0.083 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HSP70 PF00012.20 EGF83438.1 - 2.2e-259 861.7 6.8 2.5e-259 861.5 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGF83438.1 - 4.3e-16 58.7 0.1 8.7e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGF83438.1 - 0.0071 16.1 0.0 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EGF83438.1 - 0.0072 15.6 0.2 0.015 14.6 0.2 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EGF83438.1 - 0.041 13.4 0.1 8.7 5.7 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 EGF83438.1 - 0.057 12.4 0.3 0.61 9.0 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain SGS PF05002.15 EGF83439.1 - 1.2e-32 111.9 0.2 2.5e-32 110.8 0.2 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EGF83439.1 - 1.1e-12 48.8 1.3 1.8e-12 48.1 1.3 1.4 1 0 0 1 1 1 1 CS domain PGAP1 PF07819.13 EGF83441.1 - 1.4e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGF83441.1 - 3.8e-05 23.3 0.0 9.4e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGF83441.1 - 8.6e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 EGF83441.1 - 0.002 17.4 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGF83441.1 - 0.0046 16.5 0.0 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EGF83441.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Oscp1 PF10188.9 EGF83441.1 - 0.088 12.9 0.7 0.23 11.6 0.3 1.9 2 0 0 2 2 2 0 Organic solute transport protein 1 Aldedh PF00171.22 EGF83442.1 - 3.5e-126 421.4 0.0 4.3e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAS_I_H PF18314.1 EGF83443.1 - 1.3e-73 246.9 0.4 2.5e-73 246.0 0.4 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EGF83443.1 - 9.2e-61 204.9 0.1 1.6e-60 204.1 0.1 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EGF83443.1 - 2e-20 73.5 0.3 4.3e-20 72.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EGF83443.1 - 1.5e-14 54.1 0.0 3.3e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EGF83443.1 - 1.3e-12 47.7 0.0 4.9e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGF83443.1 - 0.023 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 KR domain 4PPT_N PF17837.1 EGF83443.1 - 0.63 10.2 2.6 23 5.2 2.6 2.9 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain tRNA-synt_1 PF00133.22 EGF83444.1 - 2.6e-35 121.7 0.0 2.3e-10 39.4 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGF83444.1 - 8.7e-17 60.9 0.0 3.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGF83444.1 - 4e-13 49.6 0.1 1e-12 48.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGF83444.1 - 3.8e-06 26.5 0.0 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.27 EGF83445.1 - 5.4e-52 173.7 8.3 2.1e-18 66.0 0.9 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aconitase PF00330.20 EGF83446.1 - 8e-148 493.3 0.0 1e-147 492.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGF83446.1 - 8.4e-44 149.1 0.0 1.6e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribonuc_2-5A PF06479.12 EGF83446.1 - 0.13 12.5 0.3 0.39 10.9 0.5 1.7 2 0 0 2 2 2 0 Ribonuclease 2-5A GTP_EFTU PF00009.27 EGF83447.1 - 4.8e-45 153.5 0.0 7.4e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGF83447.1 - 6e-23 80.7 0.0 1.5e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EGF83447.1 - 1.2e-21 76.7 0.0 2.7e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 EGF83447.1 - 2.4e-21 76.5 0.2 4.8e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_II PF14492.6 EGF83447.1 - 2.9e-09 36.9 0.1 6.1e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGF83447.1 - 1.8e-07 31.5 0.1 4.1e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 tRNA-synt_2 PF00152.20 EGF83449.1 - 4e-91 305.4 0.0 1.1e-90 303.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGF83449.1 - 5.5e-11 42.3 0.1 1.2e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain UPF0160 PF03690.13 EGF83449.1 - 0.001 18.8 0.3 0.0019 17.9 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) tRNA_anti-like PF12869.7 EGF83449.1 - 0.011 15.3 1.2 0.019 14.6 1.2 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF1565 PF07602.11 EGF83449.1 - 0.057 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) DUF4539 PF15072.6 EGF83449.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF4918 PF16265.5 EGF83449.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) Ribosomal_L22 PF00237.19 EGF83449.1 - 0.33 11.2 2.5 16 5.8 3.6 2.2 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e Aldedh PF00171.22 EGF83451.1 - 1.4e-114 383.1 0.0 1.7e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COX5A PF02284.16 EGF83452.1 - 9e-28 96.3 0.0 1.2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LRR_8 PF13855.6 EGF83453.1 - 6.1e-11 41.9 3.6 6.1e-11 41.9 3.6 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EGF83453.1 - 2.7e-06 27.6 17.6 3.8e-05 24.0 6.1 3.5 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGF83453.1 - 0.00012 21.8 5.2 0.063 13.4 0.5 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 EGF83453.1 - 0.0076 16.6 8.3 4.1 8.3 0.3 4.8 4 1 0 4 4 4 2 Leucine Rich Repeat FUN14 PF04930.15 EGF83454.1 - 4.7e-20 71.8 3.1 5.9e-20 71.5 3.1 1.1 1 0 0 1 1 1 1 FUN14 family Ribosomal_S26e PF01283.19 EGF83455.1 - 9.3e-50 167.6 4.0 9.3e-50 167.6 4.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S26e DegQ PF08181.11 EGF83455.1 - 0.47 10.6 8.8 0.49 10.5 1.5 4.8 3 0 0 3 3 3 0 DegQ (SacQ) family Acatn PF13000.7 EGF83456.1 - 7.6e-152 506.6 31.0 6.2e-69 232.9 15.5 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MF_alpha_N PF05436.11 EGF83457.1 - 0.018 14.9 0.4 0.039 13.8 0.4 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF3450 PF11932.8 EGF83457.1 - 0.021 14.1 0.1 0.021 14.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2099 PF09872.9 EGF83457.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) TMPIT PF07851.13 EGF83457.1 - 4.7 6.4 10.2 0.096 11.9 1.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein ORC6 PF05460.13 EGF83457.1 - 5 6.3 17.5 0.25 10.6 12.1 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Asp PF00026.23 EGF83458.1 - 1.2e-12 47.9 0.6 2.8e-12 46.7 0.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF3430 PF11912.8 EGF83458.1 - 0.043 13.9 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) TAXi_C PF14541.6 EGF83458.1 - 0.072 12.9 0.2 0.44 10.3 0.0 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal TACC_C PF05010.14 EGF83459.1 - 0.05 13.4 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sod_Fe_C PF02777.18 EGF83460.1 - 2.5e-30 104.7 0.5 2.8e-30 104.5 0.5 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain zf-DNL PF05180.12 EGF83461.1 - 1.2e-30 105.2 0.5 1.4e-30 105.1 0.5 1.0 1 0 0 1 1 1 1 DNL zinc finger ZZ PF00569.17 EGF83461.1 - 0.045 13.6 2.5 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type TFIIS_C PF01096.18 EGF83461.1 - 0.11 12.3 2.3 3.4 7.6 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Sod_Fe_C PF02777.18 EGF83462.1 - 4e-27 94.4 1.1 4.4e-27 94.2 1.1 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain BLI1 PF17324.2 EGF83463.1 - 0.042 14.5 0.5 0.64 10.7 0.5 2.1 1 1 0 1 1 1 0 BLOC-1 interactor 1 zf-Nse PF11789.8 EGF83465.1 - 8.8e-16 57.5 1.2 1.3e-15 56.9 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EGF83465.1 - 0.00011 22.3 0.8 0.00068 19.8 0.2 2.5 2 2 1 3 3 3 1 U-box domain zf-MIZ PF02891.20 EGF83465.1 - 0.00059 19.5 0.3 0.001 18.8 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 EGF83465.1 - 0.0018 18.0 0.1 0.0036 17.1 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF83465.1 - 0.0026 17.7 0.5 0.0051 16.8 0.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger ProRS-C_1 PF09180.11 EGF83466.1 - 5.7e-25 87.3 1.9 1.4e-24 86.1 1.9 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EGF83466.1 - 3.8e-18 65.4 0.0 7.3e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGF83466.1 - 3.8e-18 66.1 0.0 7.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HMG_box PF00505.19 EGF83467.1 - 1.8e-18 66.7 0.2 4e-18 65.6 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF83467.1 - 5.8e-10 39.6 0.1 1.6e-09 38.2 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 EGF83467.1 - 0.052 14.1 0.1 0.052 14.1 0.1 3.9 2 1 0 2 2 2 0 YABBY protein Kri1_C PF12936.7 EGF83468.1 - 2e-27 95.2 0.6 2e-27 95.2 0.6 5.4 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 EGF83468.1 - 1.9e-26 92.6 7.8 1.9e-26 92.6 7.8 5.8 6 1 0 6 6 6 1 KRI1-like family Chorismate_bind PF00425.18 EGF83471.1 - 2.4e-81 273.1 0.1 5.5e-81 271.9 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 EGF83471.1 - 5.1e-41 140.5 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EGF83471.1 - 1.2e-19 70.9 0.1 4.3e-19 69.1 0.1 2.0 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EGF83471.1 - 2.9e-05 23.9 0.9 0.00019 21.2 0.9 2.2 1 1 0 1 1 1 1 Peptidase C26 Glycos_transf_4 PF00953.21 EGF83472.1 - 1.2e-07 31.8 1.8 1.2e-07 31.8 1.8 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 4 DUF4395 PF14340.6 EGF83472.1 - 0.014 15.8 3.9 0.14 12.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) DUF4131 PF13567.6 EGF83472.1 - 6.3 6.4 6.7 0.27 10.9 0.6 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Glycos_transf_4 PF00953.21 EGF83473.1 - 2e-13 50.6 1.4 2e-13 50.6 1.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 Fer2_3 PF13085.6 EGF83474.1 - 2.2e-32 111.3 0.0 3.5e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGF83474.1 - 3.3e-09 37.2 6.0 3.3e-09 37.2 6.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGF83474.1 - 6.7e-07 29.7 6.8 6.7e-07 29.7 6.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGF83474.1 - 9.3e-07 28.9 3.1 9.3e-07 28.9 3.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGF83474.1 - 0.00034 20.5 2.7 0.0051 16.7 0.4 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EGF83474.1 - 0.04 14.5 8.1 0.04 14.5 8.1 2.9 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGF83474.1 - 0.065 13.4 11.1 0.037 14.2 6.8 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGF83474.1 - 2.6 9.0 10.0 4 8.4 0.9 3.1 3 1 0 3 3 3 0 4Fe-4S double cluster binding domain DUF1115 PF06544.12 EGF83475.1 - 3e-45 153.9 0.1 5.2e-45 153.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 EGF83475.1 - 6.3e-10 39.2 0.5 1.3e-09 38.1 0.1 1.8 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Leptin PF02024.15 EGF83475.1 - 0.083 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Leptin Arm PF00514.23 EGF83476.1 - 0.00018 21.4 10.0 0.00027 20.8 0.2 4.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGF83476.1 - 0.0076 16.6 0.7 0.036 14.5 0.2 2.4 3 0 0 3 3 3 1 HEAT repeats PHBC_N PF12551.8 EGF83476.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal WD40 PF00400.32 EGF83477.1 - 5.8e-20 71.2 18.4 5.3e-05 23.9 0.8 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83477.1 - 0.0013 19.0 0.1 0.27 11.6 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Mod_r PF07200.13 EGF83478.1 - 2.1e-27 96.0 12.2 2.7e-27 95.7 12.2 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UEV PF05743.13 EGF83478.1 - 0.0025 17.7 0.1 0.005 16.7 0.1 1.5 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 EGF83478.1 - 0.0078 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SKA2 PF16740.5 EGF83478.1 - 0.037 13.8 1.4 0.066 13.0 1.4 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 PhoU PF01895.19 EGF83478.1 - 0.57 10.7 3.9 0.69 10.4 1.1 2.3 1 1 1 2 2 2 0 PhoU domain LIM PF00412.22 EGF83479.1 - 1.8e-22 79.3 25.6 1.7e-11 44.2 5.6 3.1 3 0 0 3 3 3 2 LIM domain Zn_Tnp_IS1595 PF12760.7 EGF83479.1 - 0.058 13.4 19.5 0.19 11.7 6.4 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain NCD3G PF07562.14 EGF83479.1 - 0.11 12.5 19.0 0.89 9.6 4.4 3.3 3 0 0 3 3 3 0 Nine Cysteines Domain of family 3 GPCR zf_UBZ PF18439.1 EGF83479.1 - 0.15 11.6 0.3 0.15 11.6 0.3 5.0 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger PXA PF02194.15 EGF83480.1 - 3.9e-37 128.0 1.4 9.3e-37 126.8 0.5 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EGF83480.1 - 6.1e-22 78.3 0.1 1.6e-21 77.0 0.1 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EGF83480.1 - 1.6e-14 53.8 0.1 5.6e-14 52.1 0.1 2.0 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EGF83480.1 - 8.7e-05 22.8 0.0 0.00036 20.8 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain FAM72 PF14976.6 EGF83481.1 - 1.5e-34 119.2 6.1 1.7e-34 119.1 6.1 1.0 1 0 0 1 1 1 1 FAM72 protein YL1_C PF08265.11 EGF83482.1 - 1.5e-12 47.1 1.3 2.1e-12 46.6 1.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 EGF83482.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger DUF5092 PF17010.5 EGF83483.1 - 5.5e-40 137.0 0.2 1.1e-29 103.5 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF5092) B3 PF02362.21 EGF83483.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 B3 DNA binding domain WAPL PF07814.13 EGF83484.1 - 4.7e-24 84.9 11.3 5.6e-24 84.6 7.1 2.5 2 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin COX6B PF02297.17 EGF83485.1 - 0.013 15.7 0.6 0.015 15.5 0.6 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb MTCP1 PF08991.10 EGF83485.1 - 0.013 15.7 1.1 0.016 15.4 1.1 1.1 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CHCH PF06747.13 EGF83485.1 - 0.028 14.6 1.7 0.045 13.9 1.7 1.3 1 0 0 1 1 1 0 CHCH domain Pex16 PF08610.10 EGF83486.1 - 2.8e-98 329.1 0.6 3.2e-98 328.9 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ANAPC4_WD40 PF12894.7 EGF83487.1 - 8.6e-15 54.8 0.0 0.00011 22.4 0.0 6.0 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF83487.1 - 3.3e-10 40.4 12.5 4.4e-05 24.2 0.1 7.3 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.11 EGF83487.1 - 2e-08 34.4 0.3 0.56 10.1 0.0 5.4 3 3 2 5 5 5 4 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 EGF83487.1 - 4.7e-06 25.6 0.4 0.55 8.9 0.0 4.9 5 1 0 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 EGF83487.1 - 0.0032 17.4 9.0 0.68 10.0 0.2 5.5 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EGF83487.1 - 0.011 13.8 0.6 0.44 8.5 0.0 2.8 3 1 0 3 3 3 0 IKI3 family Coatomer_WDAD PF04053.14 EGF83487.1 - 0.079 12.0 0.1 74 2.2 0.0 4.0 3 2 2 5 5 5 0 Coatomer WD associated region RGS PF00615.19 EGF83488.1 - 1.5e-13 51.1 0.2 6e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.11 EGF83488.1 - 0.01 15.6 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Glyco_hydro_16 PF00722.21 EGF83489.1 - 5.1e-28 97.7 0.3 7.6e-28 97.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cg6151-P PF10233.9 EGF83491.1 - 5e-24 84.8 13.7 6.6e-24 84.4 13.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF5592 PF17332.2 EGF83491.1 - 0.021 15.3 1.7 0.021 15.3 1.7 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5592) DUF4870 PF09685.10 EGF83491.1 - 0.39 10.8 9.2 1.9 8.6 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) DUF1189 PF06691.11 EGF83491.1 - 6.6 6.2 14.2 3.1 7.3 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) TAF4 PF05236.14 EGF83492.1 - 5.5e-25 88.7 5.9 5.5e-25 88.7 5.9 5.0 2 2 1 4 4 4 1 Transcription initiation factor TFIID component TAF4 family SDA1 PF05285.12 EGF83492.1 - 2.4 7.5 41.7 0.12 11.8 35.4 1.9 2 0 0 2 2 2 0 SDA1 Methyltransf_11 PF08241.12 EGF83493.1 - 2.5e-15 56.9 0.0 5.2e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF83493.1 - 1.8e-12 47.8 0.1 9.1e-12 45.5 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF83493.1 - 3.6e-07 30.2 0.0 5.8e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF83493.1 - 1.2e-06 28.3 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF83493.1 - 1e-05 26.2 0.0 3.3e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EGF83493.1 - 0.0019 16.8 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EGF83493.1 - 0.0032 16.8 0.0 0.0063 15.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGF83493.1 - 0.0054 16.4 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW ER_lumen_recept PF00810.18 EGF83494.1 - 6.5e-52 176.3 9.7 1e-51 175.6 9.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGF83494.1 - 0.058 13.2 8.2 2.1 8.2 0.1 3.4 3 0 0 3 3 3 0 PQ loop repeat Tlr3_TMD PF17968.1 EGF83494.1 - 7.1 6.9 9.4 5.6 7.2 0.0 3.4 3 0 0 3 3 3 0 Toll-like receptor 3 trans-membrane domain RabGAP-TBC PF00566.18 EGF83495.1 - 2.2e-46 158.2 1.7 3.6e-46 157.5 0.5 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGF83495.1 - 8.2e-05 22.2 1.3 0.00032 20.4 1.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EGF83495.1 - 0.00057 20.3 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGF83495.1 - 0.0046 16.4 1.2 0.0046 16.4 1.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGF83495.1 - 0.023 14.2 0.4 0.057 12.9 0.4 1.6 1 0 0 1 1 1 0 EF hand bZIP_2 PF07716.15 EGF83496.1 - 1.5e-05 25.0 12.4 2.1e-05 24.5 11.4 1.8 1 1 0 1 1 1 1 Basic region leucine zipper NRBF2 PF08961.10 EGF83496.1 - 0.001 18.7 2.2 0.0019 17.8 2.2 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 EGF83496.1 - 0.0013 18.8 13.4 0.065 13.3 7.7 2.5 1 1 1 2 2 2 2 bZIP transcription factor Sec20 PF03908.13 EGF83497.1 - 3.3e-17 62.2 0.6 3.3e-17 62.2 0.6 2.9 2 1 1 3 3 3 1 Sec20 V-SNARE_C PF12352.8 EGF83497.1 - 0.0017 18.6 1.9 0.0017 18.6 1.9 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus BORCS8 PF10167.9 EGF83497.1 - 0.099 12.6 3.0 0.37 10.7 0.4 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 CortBP2 PF09727.9 EGF83497.1 - 0.34 10.8 7.2 1.6 8.6 7.4 1.9 1 1 0 1 1 1 0 Cortactin-binding protein-2 PAP2_3 PF14378.6 EGF83498.1 - 2.1e-24 86.3 12.0 2.6e-24 86.0 12.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EGF83498.1 - 5.9e-07 29.3 8.6 5.9e-07 29.3 8.6 2.2 1 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EGF83498.1 - 0.042 14.4 5.6 0.042 14.4 5.6 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Snapin_Pallidin PF14712.6 EGF83500.1 - 3.3e-16 59.5 0.2 4.8e-16 59.0 0.2 1.3 1 1 0 1 1 1 1 Snapin/Pallidin Translin PF01997.16 EGF83500.1 - 0.043 13.8 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Translin family CorA PF01544.18 EGF83500.1 - 0.066 12.5 0.1 0.071 12.4 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HLH PF00010.26 EGF83502.1 - 4.5e-11 42.5 0.2 7.7e-11 41.8 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ABC_membrane PF00664.23 EGF83503.1 - 8.4e-64 215.9 48.7 6e-34 117.9 22.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF83503.1 - 2.6e-48 164.0 0.0 2.8e-24 86.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGF83503.1 - 7.7e-10 38.6 1.9 0.29 10.5 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF83503.1 - 4e-08 33.3 0.7 0.013 15.6 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGF83503.1 - 7.5e-07 29.8 0.2 0.023 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGF83503.1 - 9.8e-07 28.8 0.0 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGF83503.1 - 2.2e-06 27.8 2.6 0.0037 17.3 0.4 2.9 3 0 0 3 3 2 2 Dynamin family AAA_29 PF13555.6 EGF83503.1 - 2.5e-06 27.1 0.1 0.12 12.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGF83503.1 - 6.8e-06 26.6 0.2 0.016 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGF83503.1 - 9.7e-05 22.3 2.7 0.15 11.8 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 EGF83503.1 - 0.00011 21.3 0.3 0.02 13.9 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EGF83503.1 - 0.0034 17.2 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Spore_IV_A PF09547.10 EGF83503.1 - 0.0034 16.4 0.0 0.16 10.9 0.0 2.3 2 0 0 2 2 2 1 Stage IV sporulation protein A (spore_IV_A) T2SSE PF00437.20 EGF83503.1 - 0.0065 15.6 0.0 0.31 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGF83503.1 - 0.008 16.4 0.7 4.3 7.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain IIGP PF05049.13 EGF83503.1 - 0.01 14.9 0.5 0.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) KAP_NTPase PF07693.14 EGF83503.1 - 0.01 15.1 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 EGF83503.1 - 0.011 15.2 0.1 3 7.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 EGF83503.1 - 0.017 14.7 1.3 0.37 10.3 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EGF83503.1 - 0.024 14.7 1.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EGF83503.1 - 0.036 13.3 0.4 2.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGF83503.1 - 0.045 13.1 0.3 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 EGF83503.1 - 0.051 12.7 0.1 5.6 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.15 EGF83503.1 - 0.053 12.3 0.6 3.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 EGF83503.1 - 0.056 13.2 0.4 18 5.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGF83503.1 - 0.083 12.6 0.3 0.6 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF83503.1 - 0.09 13.2 0.1 15 6.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EGF83503.1 - 0.096 13.2 2.1 2.2 8.8 0.5 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGF83503.1 - 0.098 11.5 0.5 1 8.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 EGF83503.1 - 0.11 12.4 1.1 33 4.3 0.1 3.4 3 0 0 3 3 3 0 NTPase PRK PF00485.18 EGF83503.1 - 0.32 10.7 1.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 EGF83503.1 - 0.47 10.2 4.8 12 5.6 0.6 3.1 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Ceramidase PF05875.12 EGF83504.1 - 2.3e-65 220.6 10.9 3.1e-65 220.2 10.9 1.1 1 0 0 1 1 1 1 Ceramidase CcmD PF04995.14 EGF83504.1 - 0.17 12.0 2.6 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Tctex-1 PF03645.13 EGF83505.1 - 2.1e-34 117.8 1.1 2.4e-34 117.7 1.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Glycogen_syn PF05693.13 EGF83506.1 - 1.3e-300 998.6 1.0 1.3e-202 674.8 0.1 2.0 1 1 1 2 2 2 2 Glycogen synthase Glyco_transf_5 PF08323.11 EGF83506.1 - 1.2e-07 31.7 0.2 2.8e-07 30.5 0.2 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGF83506.1 - 4.4e-06 26.3 0.0 0.00075 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGF83506.1 - 6.5e-06 26.6 0.0 0.0035 17.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGF83506.1 - 1.2e-05 25.4 0.1 2.9e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGF83506.1 - 5.2e-05 23.8 0.1 0.00011 22.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Phage_hub_GP28 PF11110.8 EGF83506.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Baseplate hub distal subunit Pkinase PF00069.25 EGF83507.1 - 2.1e-57 194.5 0.0 1.5e-56 191.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83507.1 - 5.3e-27 94.7 0.1 1.3e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF83507.1 - 1.2e-06 27.7 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 EGF83507.1 - 0.0054 17.4 0.8 0.0054 17.4 0.8 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.23 EGF83507.1 - 0.0082 16.1 0.0 0.57 10.1 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF83507.1 - 0.0088 15.4 0.2 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGF83507.1 - 0.07 12.4 0.1 0.51 9.6 0.0 2.4 3 0 0 3 3 3 0 Kinase-like TPT PF03151.16 EGF83508.1 - 8.4e-29 100.8 18.2 1.1e-28 100.5 18.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGF83508.1 - 5.6e-13 49.2 33.5 6.7e-08 32.8 7.4 2.6 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGF83508.1 - 4.1e-06 26.2 22.0 4.1e-06 26.2 22.0 1.9 1 1 1 2 2 2 1 UAA transporter family PRELI PF04707.14 EGF83509.1 - 6.5e-42 143.0 0.2 7.6e-42 142.8 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Lipocalin_7 PF14651.6 EGF83509.1 - 0.086 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family WD40 PF00400.32 EGF83510.1 - 1.1e-13 51.4 4.8 0.011 16.5 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat HEAT_2 PF13646.6 EGF83510.1 - 1.1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 EGF83510.1 - 3.4e-05 23.7 0.0 0.58 10.6 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Dicer_dimer PF03368.14 EGF83510.1 - 0.0058 16.8 0.4 0.1 12.8 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain RasGEF_N_2 PF14663.6 EGF83510.1 - 0.026 14.9 0.0 0.14 12.6 0.0 2.2 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SGL PF08450.12 EGF83510.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region LRR_6 PF13516.6 EGF83511.1 - 1.5e-10 40.2 3.8 0.0023 17.9 0.1 5.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EGF83511.1 - 0.014 15.9 0.1 12 6.9 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 EGF83513.1 - 1.1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83513.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase SRP40_C PF05022.12 EGF83514.1 - 0.1 13.5 1.2 14 6.6 0.0 2.5 2 0 0 2 2 2 0 SRP40, C-terminal domain EF-hand_1 PF00036.32 EGF83515.1 - 1.3e-19 68.2 2.1 7.6e-07 28.2 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGF83515.1 - 1.3e-16 59.0 0.8 4.4e-05 23.1 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGF83515.1 - 1.7e-14 54.0 0.1 1.7e-08 34.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGF83515.1 - 6.2e-12 45.2 0.6 6.7e-07 29.1 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGF83515.1 - 1.4e-10 40.2 0.9 0.0005 19.5 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EGF83515.1 - 0.0013 19.0 0.0 0.8 10.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain CCD48 PF15799.5 EGF83515.1 - 0.031 12.6 0.0 0.04 12.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 FlgD PF03963.14 EGF83515.1 - 0.068 13.5 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region DUF5640 PF18692.1 EGF83515.1 - 0.14 12.2 0.0 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5640) Ribosomal_L24e PF01246.20 EGF83516.1 - 9.2e-33 112.3 7.8 9.2e-33 112.3 7.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 EGF83516.1 - 0.026 14.5 9.2 0.06 13.3 9.2 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HAGH_C PF16123.5 EGF83516.1 - 0.063 13.8 1.4 0.097 13.2 0.8 1.6 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus DUF2116 PF09889.9 EGF83516.1 - 2.6 8.1 6.5 0.35 10.9 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YHS PF04945.13 EGF83516.1 - 2.9 8.0 8.3 0.88 9.7 0.4 2.3 2 0 0 2 2 2 0 YHS domain zf-RING_2 PF13639.6 EGF83517.1 - 2.2e-08 34.3 6.6 3.5e-08 33.7 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGF83517.1 - 6.1e-06 25.9 2.6 1.2e-05 24.9 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGF83517.1 - 9.7e-06 25.3 5.2 1.7e-05 24.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGF83517.1 - 3.6e-05 24.0 6.2 7e-05 23.0 6.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGF83517.1 - 4.8e-05 23.2 5.5 7.5e-05 22.6 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF83517.1 - 0.00019 21.2 5.8 0.00032 20.5 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF83517.1 - 0.00022 21.2 4.1 0.00023 21.1 1.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF83517.1 - 0.0053 16.6 3.8 0.0085 15.9 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGF83517.1 - 0.02 14.9 3.2 0.048 13.7 3.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 EGF83517.1 - 0.059 13.5 1.0 0.1 12.7 1.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 EGF83517.1 - 0.068 13.3 1.6 0.11 12.6 1.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zf_RING PF16744.5 EGF83517.1 - 0.071 13.2 2.4 0.13 12.4 2.4 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 EGF83517.1 - 0.11 12.1 5.9 0.24 11.0 5.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGF83517.1 - 0.23 11.7 7.2 5.1 7.3 7.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.7 EGF83517.1 - 0.25 11.4 2.8 0.63 10.1 2.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-C3H2C3 PF17122.5 EGF83517.1 - 1.9 8.6 6.3 7.7 6.6 6.3 2.1 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 EGF83517.1 - 1.9 8.4 5.4 3.6 7.5 5.4 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EGF83517.1 - 5.7 6.9 7.1 2.2 8.2 3.0 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1397 PF07165.11 EGF83518.1 - 0.016 14.7 0.2 0.022 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) PTS_IIA PF02255.16 EGF83518.1 - 0.071 13.2 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Nitrate_red_del PF02613.15 EGF83518.1 - 0.075 13.0 0.3 0.15 12.1 0.3 1.5 2 0 0 2 2 2 0 Nitrate reductase delta subunit Orf78 PF06024.12 EGF83518.1 - 0.098 13.0 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) RGS PF00615.19 EGF83519.1 - 6e-15 55.5 0.0 9.1e-05 22.7 0.0 4.5 3 1 0 3 3 3 3 Regulator of G protein signaling domain VirE2 PF07229.12 EGF83519.1 - 0.33 9.6 5.0 0.89 8.1 4.5 1.8 2 0 0 2 2 2 0 VirE2 SprA-related PF12118.8 EGF83519.1 - 7.8 5.5 26.2 5.9 5.9 2.1 2.3 2 0 0 2 2 2 0 SprA-related family Pkinase PF00069.25 EGF83520.1 - 1.2e-70 238.0 0.0 2.4e-70 236.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83520.1 - 2.5e-30 105.6 0.0 1.5e-22 80.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF83520.1 - 6.2e-05 22.4 0.3 0.87 8.8 0.0 3.0 2 1 0 3 3 3 2 Kinase-like APH PF01636.23 EGF83520.1 - 0.0037 17.2 0.1 2.3 8.1 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGF83520.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGF83520.1 - 0.12 11.3 0.1 0.53 9.2 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 EGF83520.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_Mig-6 PF11555.8 EGF83520.1 - 0.25 11.5 2.5 0.89 9.7 0.0 3.0 4 0 0 4 4 4 0 EGFR receptor inhibitor Mig-6 Sec1 PF00995.23 EGF83521.1 - 6.9e-135 451.5 3.0 8.2e-135 451.2 3.0 1.1 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 EGF83521.1 - 0.0074 16.3 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain Not1 PF04054.15 EGF83521.1 - 0.0079 15.2 0.8 0.052 12.5 0.7 2.0 1 1 1 2 2 2 1 CCR4-Not complex component, Not1 Inj_translocase PF16928.5 EGF83521.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome SPRY PF00622.28 EGF83522.1 - 1.6e-12 47.5 0.8 3.7e-05 23.8 0.1 3.1 3 0 0 3 3 3 2 SPRY domain Forkhead PF00250.18 EGF83522.1 - 0.00022 21.4 0.5 0.0013 18.9 0.1 2.2 2 0 0 2 2 2 1 Forkhead domain PHD PF00628.29 EGF83522.1 - 0.44 10.5 18.6 0.31 11.0 16.6 1.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_2 PF14445.6 EGF83522.1 - 5.4 7.3 14.3 7.8e+02 0.3 14.3 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 ABC_membrane PF00664.23 EGF83523.1 - 1e-55 189.3 37.4 4.8e-38 131.4 15.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF83523.1 - 3.2e-48 163.7 1.2 6.9e-29 101.1 0.1 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EGF83523.1 - 3.4e-10 39.7 7.8 0.027 13.9 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGF83523.1 - 1.2e-05 25.0 2.5 0.072 12.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF83523.1 - 1.3e-05 25.3 0.8 0.053 13.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGF83523.1 - 4.3e-05 23.5 0.2 0.57 9.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGF83523.1 - 0.00011 22.7 0.1 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGF83523.1 - 0.00053 19.9 0.1 0.58 10.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EGF83523.1 - 0.00065 18.9 0.3 0.46 9.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 EGF83523.1 - 0.00086 19.5 1.9 0.018 15.2 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 EGF83523.1 - 0.0024 17.1 0.4 0.28 10.3 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EGF83523.1 - 0.0027 17.6 0.3 2.5 8.0 0.0 2.9 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 EGF83523.1 - 0.0045 16.4 0.5 0.66 9.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_13 PF13166.6 EGF83523.1 - 0.0045 15.7 0.2 0.0085 14.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGF83523.1 - 0.0053 16.3 0.3 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 EGF83523.1 - 0.0056 16.7 2.4 0.47 10.5 0.3 2.5 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 EGF83523.1 - 0.0088 15.9 0.4 2.2 8.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGF83523.1 - 0.0098 15.6 0.4 3.9 7.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGF83523.1 - 0.01 16.3 2.2 3.8 7.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGF83523.1 - 0.017 15.4 5.4 1.1 9.6 0.5 3.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGF83523.1 - 0.031 14.6 0.2 2 8.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 EGF83523.1 - 0.042 13.4 1.0 8 6.0 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EGF83523.1 - 0.051 13.1 0.2 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGF83523.1 - 0.056 13.2 0.2 7.4 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGF83523.1 - 0.085 12.9 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGF83523.1 - 0.11 12.7 0.8 18 5.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGF83523.1 - 0.12 12.2 1.7 14 5.6 0.1 3.2 3 0 0 3 3 3 0 NTPase DUF334 PF03904.13 EGF83523.1 - 0.76 9.3 9.9 3.3 7.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF334) RseC_MucC PF04246.12 EGF83523.1 - 1 9.3 8.2 3.8 7.5 1.3 3.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EF-hand_7 PF13499.6 EGF83524.1 - 0.0077 16.7 3.0 0.01 16.3 0.4 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGF83524.1 - 0.017 15.0 0.1 0.098 12.6 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain DUF2203 PF09969.9 EGF83524.1 - 2.1 9.1 9.8 6.5 7.5 0.6 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fer4 PF00037.27 EGF83525.1 - 1.9e-14 52.7 16.4 1.7e-08 33.9 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGF83525.1 - 6.6e-13 49.0 10.4 1.1e-12 48.3 10.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGF83525.1 - 7e-11 42.9 5.6 4e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGF83525.1 - 4.9e-10 39.4 4.0 0.00014 22.0 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGF83525.1 - 9.7e-09 35.3 10.2 1.6e-08 34.5 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGF83525.1 - 1.9e-08 34.3 21.4 4.8e-06 26.6 12.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGF83525.1 - 3.8e-07 29.9 17.8 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EGF83525.1 - 7.5e-07 29.5 18.9 0.00034 21.0 11.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGF83525.1 - 1.3e-06 28.1 12.5 0.0027 17.7 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGF83525.1 - 1.3e-05 25.3 12.0 0.00049 20.4 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGF83525.1 - 0.00014 22.4 10.6 0.043 14.4 12.5 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGF83525.1 - 0.012 16.1 14.6 0.64 10.6 2.6 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EGF83525.1 - 0.039 14.1 8.8 1.1 9.5 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGF83525.1 - 0.044 14.0 6.1 1.2 9.4 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Alginate_lyase PF05426.12 EGF83525.1 - 0.083 12.4 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Alginate lyase Fer4_3 PF12798.7 EGF83525.1 - 0.2 12.7 16.3 0.34 12.0 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 EGF83525.1 - 0.21 11.7 5.8 1.7 8.8 0.7 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EGF83525.1 - 0.59 11.0 11.8 2.7 8.9 1.8 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain RNase_PH PF01138.21 EGF83526.1 - 5.3e-20 72.3 0.0 7.9e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGF83526.1 - 6e-10 39.0 0.1 1.3e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Hid1 PF12722.7 EGF83527.1 - 1.5e-158 529.5 0.1 9.2e-79 265.6 0.1 2.0 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGF83527.1 - 1.1e-93 314.8 0.0 1.3e-53 182.4 0.0 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein ASXH PF13919.6 EGF83528.1 - 9.8e-24 84.0 1.9 2.2e-23 82.8 1.9 1.6 1 0 0 1 1 1 1 Asx homology domain Glyco_transf_34 PF05637.12 EGF83528.1 - 1.1 8.9 4.2 17 5.0 0.1 3.0 3 0 0 3 3 3 0 galactosyl transferase GMA12/MNN10 family Peptidase_C12 PF01088.21 EGF83529.1 - 7.4e-58 195.8 0.0 1.9e-57 194.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGF83529.1 - 3.1e-12 46.2 1.0 6.8e-12 45.1 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Preseq_ALAS PF09029.10 EGF83530.1 - 0.024 15.1 0.0 0.1 13.1 0.0 1.9 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence MMR_HSR1 PF01926.23 EGF83532.1 - 3e-08 33.7 0.2 8.8e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGF83532.1 - 9.4e-07 28.5 0.4 0.019 14.5 0.1 2.6 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGF83532.1 - 4.8e-06 26.6 0.1 9.5e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EGF83532.1 - 1.4e-05 24.8 0.2 0.00017 21.2 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 EGF83532.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 EGF83532.1 - 0.061 12.3 0.1 0.19 10.7 0.0 1.5 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGF83532.1 - 0.068 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 EGF83532.1 - 0.17 12.1 0.1 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2333 PF10095.9 EGF83534.1 - 0.03 13.3 1.5 0.052 12.5 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Peptidase_M41 PF01434.18 EGF83535.1 - 5.6e-64 215.5 0.1 8.1e-64 215.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGF83535.1 - 3.3e-43 147.3 0.0 7.5e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF83535.1 - 2.7e-11 43.1 0.1 6.4e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EGF83535.1 - 3.3e-09 37.1 0.2 1.2e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EGF83535.1 - 0.00051 20.0 0.0 0.018 15.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGF83535.1 - 0.005 16.1 0.0 0.009 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGF83535.1 - 0.0067 16.7 0.0 0.59 10.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGF83535.1 - 0.0078 16.6 0.2 0.19 12.1 0.2 2.7 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGF83535.1 - 0.008 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGF83535.1 - 0.0094 16.1 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EGF83535.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGF83535.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein CDC45 PF02724.14 EGF83535.1 - 0.2 9.9 3.0 0.31 9.3 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_28 PF13521.6 EGF83535.1 - 0.2 11.9 0.1 0.48 10.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.13 EGF83535.1 - 0.49 9.1 3.2 0.73 8.6 3.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 EGF83535.1 - 0.92 9.3 8.1 29 4.4 0.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein SAPS PF04499.15 EGF83535.1 - 1.8 7.2 4.4 35 3.0 5.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Sec3_C PF09763.9 EGF83535.1 - 9.1 4.5 6.5 16 3.7 6.5 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 CLAMP PF14769.6 EGF83536.1 - 1.6e-31 108.6 8.2 4e-31 107.4 8.2 1.7 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 WD40 PF00400.32 EGF83538.1 - 9.5e-30 102.2 11.2 4.2e-09 36.9 0.1 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83538.1 - 1.7e-10 41.0 0.0 0.0048 17.2 0.0 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cep57_MT_bd PF06657.13 EGF83538.1 - 0.053 14.0 0.6 0.9 10.0 0.4 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 bZIP_1 PF00170.21 EGF83538.1 - 0.14 12.2 4.3 0.28 11.3 4.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor zf-C2H2 PF00096.26 EGF83539.1 - 7.9e-07 29.2 17.3 5.7e-05 23.4 2.1 3.4 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGF83539.1 - 1.2e-05 25.2 0.5 1.2e-05 25.2 0.5 2.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF83539.1 - 2.5e-05 24.5 2.1 2.5e-05 24.5 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF83539.1 - 0.00016 22.2 1.0 0.00016 22.2 1.0 3.1 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF83539.1 - 0.0033 17.7 1.9 0.0078 16.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGF83539.1 - 0.031 14.2 0.8 0.083 12.8 0.8 1.9 1 1 0 1 1 1 0 zinc-finger of a C2HC-type zf-UDP PF14569.6 EGF83539.1 - 0.036 14.2 2.4 0.57 10.3 2.4 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-met PF12874.7 EGF83539.1 - 0.088 13.2 3.4 0.1 13.1 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGF83539.1 - 0.18 12.2 5.5 0.16 12.3 1.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EGF83539.1 - 1.2 9.7 7.1 0.4 11.2 0.8 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger tRNA-synt_1b PF00579.25 EGF83541.1 - 0.087 12.1 0.1 0.089 12.1 0.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Not3 PF04065.15 EGF83542.1 - 2.4e-88 295.5 26.2 3.7e-88 294.9 26.2 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGF83542.1 - 6.8e-43 145.9 11.5 1.8e-42 144.5 11.5 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DASH_Dad2 PF08654.10 EGF83542.1 - 0.33 11.4 7.4 2 8.9 0.6 3.3 2 1 0 3 3 3 0 DASH complex subunit Dad2 Syntaxin_2 PF14523.6 EGF83542.1 - 0.69 10.3 14.0 0.096 13.1 3.2 2.6 2 0 0 2 2 2 0 Syntaxin-like protein DUF3568 PF12092.8 EGF83542.1 - 2 8.5 5.3 0.37 10.9 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3568) FlxA PF14282.6 EGF83542.1 - 4.1 7.5 17.8 0.93 9.5 2.5 2.6 1 1 1 2 2 2 0 FlxA-like protein Ribosomal_L12 PF00542.19 EGF83543.1 - 6.8e-24 84.0 11.2 1.2e-22 80.0 6.4 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGF83543.1 - 1.9e-12 46.7 7.1 2e-12 46.6 4.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain CSTF2_hinge PF14327.6 EGF83543.1 - 0.078 13.4 1.6 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Ribosomal_60s PF00428.19 EGF83543.1 - 2.6 8.7 17.7 0.33 11.5 9.3 2.6 2 2 0 2 2 2 0 60s Acidic ribosomal protein CDT1 PF08839.11 EGF83544.1 - 3.9e-44 151.0 0.3 9.9e-44 149.7 0.3 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 EGF83544.1 - 1.1e-13 51.4 1.6 1.7e-12 47.6 0.1 3.5 4 0 0 4 4 4 1 DNA replication factor Cdt1 C-terminal domain zf-C2H2 PF00096.26 EGF83546.1 - 2e-06 27.9 10.1 0.00055 20.3 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF83546.1 - 5.5e-06 26.6 6.1 9e-06 25.9 1.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF83546.1 - 0.00045 20.8 8.2 0.011 16.5 1.2 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGF83546.1 - 0.61 9.9 3.3 2.8 7.8 0.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Baculo_PEP_C PF04513.12 EGF83547.1 - 5.2e-05 23.3 19.5 0.018 15.1 2.9 4.3 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EGF83547.1 - 0.00034 21.0 1.7 1.2 9.6 0.0 4.1 4 0 0 4 4 4 1 Nucleopolyhedrovirus P10 protein CPSase_sm_chain PF00988.22 EGF83547.1 - 0.12 12.2 0.3 0.29 11.0 0.3 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain MarR_2 PF12802.7 EGF83548.1 - 0.00019 21.2 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EGF83548.1 - 0.0004 19.9 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding GATA PF00320.27 EGF83548.1 - 0.001 18.6 6.5 0.0022 17.6 6.5 1.6 1 0 0 1 1 1 1 GATA zinc finger HTH_11 PF08279.12 EGF83548.1 - 0.0014 18.6 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 HTH domain Fe_dep_repress PF01325.19 EGF83548.1 - 0.0015 18.7 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 EGF83548.1 - 0.0023 18.2 0.0 0.0035 17.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 EGF83548.1 - 0.0053 16.7 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 EGF83548.1 - 0.0066 16.3 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FYVE_2 PF02318.16 EGF83548.1 - 0.0076 16.5 0.5 0.013 15.7 0.1 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger HrcA_DNA-bdg PF03444.15 EGF83548.1 - 0.0088 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TFIIE_alpha PF02002.17 EGF83548.1 - 0.035 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_Mga PF08280.11 EGF83548.1 - 0.038 14.0 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain OrfB_Zn_ribbon PF07282.11 EGF83548.1 - 0.045 13.7 0.7 0.069 13.1 0.7 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ArsR PF09824.9 EGF83548.1 - 0.056 13.1 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Zn-ribbon_8 PF09723.10 EGF83548.1 - 0.08 13.1 0.6 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 Zinc ribbon domain GntR PF00392.21 EGF83548.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF4428 PF14471.6 EGF83548.1 - 0.13 12.2 1.4 0.19 11.7 0.7 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4428) HTH_DeoR PF08220.12 EGF83548.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain zf-C2H2_3 PF13878.6 EGF83548.1 - 0.21 11.4 4.5 2 8.3 0.5 2.3 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO FeoC PF09012.10 EGF83548.1 - 1.6 8.9 3.8 8.1 6.6 0.4 2.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator cNMP_binding PF00027.29 EGF83549.1 - 7.6e-43 144.5 0.1 1.1e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EGF83549.1 - 1e-09 37.9 0.1 2e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GATA PF00320.27 EGF83550.1 - 2.1e-13 49.6 6.4 4e-13 48.7 6.4 1.5 1 0 0 1 1 1 1 GATA zinc finger Sec7 PF01369.20 EGF83551.1 - 2.2e-05 24.2 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGF83551.1 - 0.0096 16.4 0.2 0.027 15.0 0.2 1.8 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 EGF83553.1 - 8.3e-05 22.4 0.1 0.00016 21.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF83553.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 SH3 domain SBP56 PF05694.11 EGF83553.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) Glycophorin_A PF01102.18 EGF83553.1 - 0.045 14.0 0.4 0.18 12.0 0.2 2.2 1 1 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 EGF83553.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.6 EGF83553.1 - 0.062 13.1 0.0 0.062 13.1 0.0 2.1 3 0 0 3 3 3 0 Transmembrane protein 51 SH3_2 PF07653.17 EGF83553.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain LRR19-TM PF15176.6 EGF83553.1 - 0.16 12.0 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain HNH_2 PF13391.6 EGF83554.1 - 0.00016 21.8 0.2 0.00063 19.8 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Paired_CXXCH_1 PF09699.10 EGF83554.1 - 0.31 10.8 2.6 8.7 6.2 0.1 2.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) GyrB_insert PF18053.1 EGF83555.1 - 0.032 14.1 0.1 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain GntR PF00392.21 EGF83555.1 - 0.12 12.0 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Aldose_epim PF01263.20 EGF83556.1 - 6.7e-22 78.2 0.2 9.3e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase DUF402 PF04167.13 EGF83556.1 - 0.044 14.0 0.2 0.12 12.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF402) DEAD PF00270.29 EGF83557.1 - 5.9e-38 130.4 0.2 1e-37 129.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF83557.1 - 1.4e-27 96.2 0.3 4.6e-25 88.1 0.1 2.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGF83557.1 - 2.8e-06 27.4 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGF83557.1 - 0.00013 21.4 0.1 0.00026 20.4 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF530 PF04409.12 EGF83557.1 - 0.04 12.3 0.7 0.054 11.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF530) AAA_16 PF13191.6 EGF83557.1 - 0.094 13.1 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TPR_1 PF00515.28 EGF83560.1 - 1.5e-11 43.6 0.2 0.00022 20.9 0.0 7.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGF83560.1 - 3.4e-09 36.8 0.1 0.069 14.0 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF83560.1 - 1.2e-08 34.4 2.4 0.0027 17.7 0.0 7.5 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF83560.1 - 1.7e-07 31.1 0.1 0.006 16.9 0.0 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF83560.1 - 3.4e-07 29.8 0.0 0.0033 17.1 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 EGF83560.1 - 1.8e-06 28.1 0.7 0.15 12.4 0.0 5.3 5 1 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGF83560.1 - 0.00025 21.1 0.9 0.019 15.1 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF83560.1 - 0.00038 20.9 1.1 2 9.0 0.0 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF83560.1 - 0.00065 19.6 0.0 38 4.6 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGF83560.1 - 0.00083 19.4 0.1 0.0058 16.7 0.0 2.4 3 0 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_16 PF13432.6 EGF83560.1 - 0.0044 17.6 0.0 0.34 11.6 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGF83560.1 - 0.0064 16.6 0.1 6 7.3 0.0 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGF83560.1 - 0.035 14.4 0.4 0.39 11.1 0.0 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF83560.1 - 0.34 11.7 2.2 1.3e+02 3.5 0.0 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EGF83561.1 - 2e-14 53.9 0.1 8.3e-14 51.8 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGF83561.1 - 2.3e-08 34.9 0.0 2.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGF83561.1 - 2.3e-07 30.3 0.0 5.1e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EGF83561.1 - 0.0059 16.2 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 EGF83561.1 - 0.037 14.0 0.1 3.8 7.4 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Kelch_2 PF07646.15 EGF83561.1 - 0.11 12.5 0.2 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Kelch motif ANAPC4_WD40 PF12894.7 EGF83562.1 - 3.3e-06 27.3 0.0 2.4 8.5 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF83562.1 - 5.8e-05 23.8 3.6 0.33 11.9 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat CAAP1 PF15335.6 EGF83564.1 - 0.056 14.0 0.7 0.72 10.4 0.1 2.4 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Vps53_N PF04100.12 EGF83565.1 - 9.8e-106 353.9 16.3 9.8e-106 353.9 16.3 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 EGF83565.1 - 5.1e-07 29.3 17.0 2.2e-05 23.9 12.6 2.4 2 0 0 2 2 2 2 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 EGF83565.1 - 0.00023 21.1 0.0 0.00023 21.1 0.0 3.5 2 2 1 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps51 PF08700.11 EGF83565.1 - 0.0022 18.1 0.3 0.0022 18.1 0.3 3.1 3 1 0 3 3 2 1 Vps51/Vps67 NBD94 PF16830.5 EGF83565.1 - 0.0072 16.7 5.7 0.025 15.0 5.7 2.0 1 0 0 1 1 1 1 Nucleotide-Binding Domain 94 of RH Spc7 PF08317.11 EGF83565.1 - 0.033 13.1 10.7 0.062 12.2 10.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 EGF83565.1 - 0.099 12.9 5.7 0.45 10.7 3.5 2.8 2 0 0 2 2 2 0 Haemolysin XhlA SKA2 PF16740.5 EGF83565.1 - 0.23 11.3 13.6 0.096 12.5 6.1 3.4 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 EGF83565.1 - 0.41 11.2 8.6 1.3 9.6 8.6 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EGF83565.1 - 0.52 10.6 9.9 1.2 9.4 7.1 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.6 EGF83565.1 - 1.6 8.8 13.3 0.18 11.8 8.3 2.1 2 0 0 2 2 2 0 FlxA-like protein MCPsignal PF00015.21 EGF83565.1 - 1.6 8.5 6.9 2.3 8.0 2.8 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CAP_N PF01213.19 EGF83565.1 - 1.9 7.9 5.1 18 4.7 5.1 2.2 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1664 PF07889.12 EGF83565.1 - 9.9 6.2 12.6 21 5.2 8.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CLP1_P PF16575.5 EGF83566.1 - 5.9e-48 163.2 0.0 4.5e-47 160.3 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGF83566.1 - 1.1e-33 116.2 0.0 2.2e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EGF83566.1 - 3e-15 56.2 0.1 9.4e-08 32.2 0.0 2.6 1 1 1 2 2 2 2 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 EGF83566.1 - 0.014 15.2 0.0 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGF83566.1 - 0.015 15.4 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 EGF83566.1 - 0.018 14.5 0.0 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EGF83566.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGF83566.1 - 0.16 11.7 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Myosin_head PF00063.21 EGF83567.1 - 0.0018 16.6 0.0 0.0019 16.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Chitin_synth_2 PF03142.15 EGF83568.1 - 4.6e-233 774.6 0.6 7.5e-233 773.9 0.2 1.5 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 EGF83568.1 - 3.8e-72 243.6 0.0 4.6e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EGF83568.1 - 1.1e-15 57.2 0.8 6.9e-14 51.5 0.4 2.9 3 0 0 3 3 3 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGF83568.1 - 5e-12 46.1 2.3 5e-12 46.1 2.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGF83568.1 - 2.2e-10 40.8 0.0 1e-08 35.4 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 EGF83568.1 - 7.3e-09 35.6 0.2 0.0031 17.6 0.0 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 EGF83568.1 - 8.6e-05 22.4 0.0 0.0066 16.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGF83568.1 - 0.0093 15.5 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 TctB PF07331.11 EGF83568.1 - 0.011 16.0 8.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Tricorn_C1 PF14684.6 EGF83568.1 - 0.18 11.9 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain Sec10 PF07393.11 EGF83569.1 - 6.2e-106 355.5 6.3 7.9e-106 355.1 6.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EGF83569.1 - 3.1e-07 30.2 0.4 6.7e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF83569.1 - 1.3e-06 28.1 0.5 3.1e-06 26.9 0.5 1.6 1 0 0 1 1 1 1 F-box domain B_lectin PF01453.24 EGF83569.1 - 0.069 13.7 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 D-mannose binding lectin TGT PF01702.18 EGF83570.1 - 3.1e-39 135.1 0.1 1.3e-36 126.5 0.1 3.2 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase HNH_2 PF13391.6 EGF83571.1 - 0.028 14.5 0.3 0.12 12.5 0.2 2.0 1 1 0 1 1 1 0 HNH endonuclease Cytochrome_C7 PF14522.6 EGF83571.1 - 0.17 11.9 0.8 2.8 8.0 0.1 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EGF83571.1 - 0.56 10.0 4.3 8.6 6.2 0.1 2.8 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF1604 PF07713.13 EGF83572.1 - 1.6e-34 117.5 0.2 1.6e-34 117.5 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGF83572.1 - 2.1e-07 30.7 0.4 5.6e-07 29.4 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGF83572.1 - 0.0013 18.8 0.3 0.0063 16.6 0.1 2.4 2 0 0 2 2 2 1 G-patch domain PBP_sp32 PF07222.12 EGF83572.1 - 0.27 10.7 5.8 1.6 8.1 3.4 2.4 2 0 0 2 2 2 0 Proacrosin binding protein sp32 ATP-synt_C PF00137.21 EGF83573.1 - 3.8e-30 104.0 35.1 1.4e-18 67.0 11.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 EGF83573.1 - 1.6 8.6 11.0 1.1 9.2 3.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2970) GerA PF03323.13 EGF83573.1 - 4.2 5.7 5.3 11 4.3 0.9 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein MFS_1 PF07690.16 EGF83574.1 - 3.6e-27 95.2 36.3 3.1e-23 82.3 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF83574.1 - 7.8e-18 64.6 3.5 7.8e-18 64.6 3.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2347 PF09804.9 EGF83575.1 - 9.7e-45 153.3 0.0 2.2e-44 152.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EGF83575.1 - 3.3e-08 32.6 0.2 1.7e-07 30.3 0.2 1.9 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EGF83575.1 - 1.9e-07 31.0 0.2 5e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EGF83575.1 - 0.02 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S41 PF03572.18 EGF83578.1 - 5.3e-11 42.4 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 MxiM PF11441.8 EGF83578.1 - 0.0029 17.9 0.1 0.0095 16.2 0.1 1.9 1 0 0 1 1 1 1 Pilot protein MxiM PDZ_4 PF17816.1 EGF83578.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Histone_HNS PF00816.21 EGF83579.1 - 0.79 10.6 6.7 8.2 7.3 2.1 2.4 1 1 1 2 2 2 0 H-NS histone family Uds1 PF15456.6 EGF83579.1 - 4.4 7.5 10.2 0.45 10.7 3.5 2.3 1 1 1 2 2 2 0 Up-regulated During Septation DUF1690 PF07956.11 EGF83579.1 - 7.8 6.9 14.7 8.4 6.8 0.7 2.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Arm PF00514.23 EGF83580.1 - 2.6e-05 24.1 0.0 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat DUF4246 PF14033.6 EGF83581.1 - 4e-84 283.3 0.2 4.5e-84 283.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Ly49 PF08391.10 EGF83582.1 - 0.022 15.1 0.3 0.046 14.1 0.0 1.7 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region OmpH PF03938.14 EGF83582.1 - 0.029 14.7 1.7 0.049 14.0 1.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 EGF83582.1 - 0.18 12.1 8.4 0.081 13.2 3.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CNDH2_M PF16869.5 EGF83582.1 - 0.19 12.4 2.6 0.21 12.2 0.5 1.9 2 0 0 2 2 2 0 PF16858 RP-C_C PF11800.8 EGF83582.1 - 0.24 11.5 8.5 2.7 8.0 1.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF4337 PF14235.6 EGF83582.1 - 0.7 10.0 4.1 0.21 11.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DASH_Spc19 PF08287.11 EGF83582.1 - 1.1 9.1 14.3 4 7.3 0.6 2.1 2 0 0 2 2 2 0 Spc19 MAS20 PF02064.15 EGF83582.1 - 2 8.5 7.6 0.56 10.3 3.3 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor PEARLI-4 PF05278.12 EGF83582.1 - 2.9 7.4 10.2 0.051 13.2 3.4 1.5 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) ADH_zinc_N PF00107.26 EGF83583.1 - 9.5e-26 90.3 0.2 1.9e-25 89.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGF83583.1 - 2.3e-23 82.1 1.1 5.3e-23 81.0 1.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EGF83583.1 - 0.004 16.5 0.1 0.0066 15.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGF83583.1 - 0.019 14.2 0.3 0.034 13.4 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EGF83583.1 - 0.047 14.7 0.0 0.1 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 EGF83583.1 - 0.057 13.7 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EGF83583.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GNVR PF13807.6 EGF83584.1 - 0.2 11.6 1.8 12 5.9 0.9 2.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase MoaE PF02391.17 EGF83587.1 - 4.8e-35 120.3 0.3 5.8e-35 120.0 0.3 1.0 1 0 0 1 1 1 1 MoaE protein PHD PF00628.29 EGF83588.1 - 0.00022 21.1 8.6 0.0005 19.9 8.6 1.7 1 0 0 1 1 1 1 PHD-finger Neprosin_AP PF14365.6 EGF83588.1 - 0.028 14.9 0.1 0.096 13.2 0.1 1.9 1 0 0 1 1 1 0 Neprosin activation peptide PHD_Oberon PF07227.11 EGF83588.1 - 0.079 12.8 4.6 0.18 11.7 4.6 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PHD_4 PF16866.5 EGF83588.1 - 0.62 10.2 4.6 1.7 8.8 4.6 1.8 1 0 0 1 1 1 0 PHD-finger cwf21 PF08312.12 EGF83589.1 - 1.4e-15 57.2 3.9 2.1e-15 56.6 3.9 1.3 1 0 0 1 1 1 1 cwf21 domain Ins134_P3_kin_N PF17927.1 EGF83589.1 - 0.075 13.4 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Sacchrp_dh_C PF16653.5 EGF83591.1 - 1.7e-87 293.9 0.0 2.5e-87 293.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 EGF83591.1 - 5.3e-26 91.5 0.0 9.7e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 EGF83591.1 - 3.7e-18 66.0 0.0 1.6e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 EGF83591.1 - 8.5e-06 25.2 0.0 0.00094 18.5 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 EGF83591.1 - 4.2e-05 23.5 0.0 8.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EGF83591.1 - 0.00038 20.5 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EGF83591.1 - 0.019 15.8 0.0 0.038 14.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EGF83591.1 - 0.021 15.3 0.0 0.056 13.9 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EGF83591.1 - 0.021 15.5 0.0 0.039 14.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EGF83591.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CTK3_C PF12350.8 EGF83592.1 - 1.6e-11 44.2 0.3 2.8e-11 43.4 0.3 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 EGF83592.1 - 2.6e-11 43.6 0.0 7.4e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 V_ATPase_I PF01496.19 EGF83593.1 - 0.0004 18.5 3.1 0.00054 18.0 3.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3627 PF12299.8 EGF83593.1 - 0.1 12.7 3.8 0.39 10.8 2.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) YARHG PF13308.6 EGF83593.1 - 0.14 12.1 3.6 8.7 6.3 0.5 3.5 2 1 1 3 3 3 0 YARHG domain NAD_binding_6 PF08030.12 EGF83593.1 - 3.6 7.7 5.3 1 9.5 2.0 1.7 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF5477 PF17571.2 EGF83594.1 - 0.08 13.1 3.6 0.13 12.4 3.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5477) DNA_pol_phi PF04931.13 EGF83594.1 - 0.11 10.6 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF5460 PF17544.2 EGF83596.1 - 0.0049 15.9 1.1 0.0062 15.6 1.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5460) HTH_30 PF13556.6 EGF83596.1 - 0.11 12.3 0.8 0.21 11.4 0.2 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain SOGA PF11365.8 EGF83597.1 - 0.8 10.9 3.3 6.3 8.0 0.3 3.4 4 0 0 4 4 4 0 Protein SOGA ABC_tran PF00005.27 EGF83598.1 - 1.8e-40 138.6 0.0 2.1e-25 89.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGF83598.1 - 1.8e-35 122.9 28.0 1e-18 68.0 8.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region IstB_IS21 PF01695.17 EGF83598.1 - 0.00044 20.0 0.4 2.4 7.8 0.0 3.5 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_29 PF13555.6 EGF83598.1 - 0.00098 18.8 0.2 0.019 14.7 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGF83598.1 - 0.0014 18.1 0.9 2.6 7.4 0.2 3.6 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGF83598.1 - 0.0023 18.4 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Pox_A32 PF04665.12 EGF83598.1 - 0.0069 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 EGF83598.1 - 0.009 16.3 0.8 0.32 11.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 EGF83598.1 - 0.039 13.9 0.2 0.75 9.7 0.1 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MobB PF03205.14 EGF83598.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.6 EGF83598.1 - 0.046 13.5 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 EGF83598.1 - 0.051 12.9 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 EGF83598.1 - 0.061 13.2 3.2 0.16 11.9 0.2 3.2 3 1 0 3 3 3 0 NACHT domain RsgA_GTPase PF03193.16 EGF83598.1 - 0.065 13.1 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase TrwB_AAD_bind PF10412.9 EGF83598.1 - 0.067 12.1 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 EGF83598.1 - 0.08 12.1 0.3 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 EGF83598.1 - 0.084 13.0 1.7 0.28 11.3 0.0 2.8 4 0 0 4 4 3 0 50S ribosome-binding GTPase cobW PF02492.19 EGF83598.1 - 0.097 12.3 0.4 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGF83598.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGF83598.1 - 0.12 12.4 0.1 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGF83598.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGF83598.1 - 0.19 12.2 0.6 0.91 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain LRR_4 PF12799.7 EGF83599.1 - 0.37 11.3 33.9 6.3 7.4 0.3 9.8 8 2 4 12 12 12 0 Leucine Rich repeats (2 copies) COQ9 PF08511.11 EGF83600.1 - 1.9e-28 98.1 0.0 3.1e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 COQ9 PACT_coil_coil PF10495.9 EGF83601.1 - 3.6e-13 49.9 1.6 7.2e-12 45.7 0.1 4.4 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TSC22 PF01166.18 EGF83601.1 - 0.0096 16.2 0.4 0.0096 16.2 0.4 22.3 23 3 2 25 25 25 3 TSC-22/dip/bun family Fer4_24 PF18109.1 EGF83601.1 - 0.015 15.5 2.3 15 5.9 0.0 4.6 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain PLAC9 PF15205.6 EGF83601.1 - 0.51 10.8 3.2 8.2 6.9 0.1 3.9 3 0 0 3 3 3 0 Placenta-specific protein 9 DUF4201 PF13870.6 EGF83602.1 - 2.5e-44 151.1 19.8 2.5e-44 151.1 19.8 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4201) CtaG_Cox11 PF04442.14 EGF83602.1 - 0.21 11.6 1.8 0.29 11.2 0.3 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein CtaG/Cox11 COG5 PF10392.9 EGF83602.1 - 4.1 7.6 12.5 0.65 10.2 5.2 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Choline_transpo PF04515.12 EGF83603.1 - 3.1e-29 102.2 17.4 3.1e-29 102.2 17.4 2.7 2 1 0 2 2 2 1 Plasma-membrane choline transporter Choline_transpo PF04515.12 EGF83604.1 - 7.2e-09 35.3 7.5 8e-09 35.1 7.5 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter WD40 PF00400.32 EGF83605.1 - 6e-06 26.9 0.2 0.0045 17.8 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat PolyA_pol PF01743.20 EGF83606.1 - 5.2e-27 94.8 0.2 2e-26 92.9 0.1 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGF83606.1 - 2.8e-07 30.2 0.0 1.2e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A JAB PF01398.21 EGF83607.1 - 4.7e-32 110.4 0.7 7.9e-32 109.7 0.7 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGF83607.1 - 2.6e-22 79.5 0.3 5.8e-22 78.4 0.3 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Phosphoesterase PF04185.14 EGF83608.1 - 1.6e-35 123.0 0.1 1.6e-33 116.4 0.1 2.3 1 1 0 1 1 1 1 Phosphoesterase family Cytochrom_B558a PF05038.13 EGF83609.1 - 2.2e-09 37.2 6.0 5.2e-08 32.7 0.6 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit Asn_synthase PF00733.21 EGF83610.1 - 8.5e-20 71.7 0.0 1.6e-09 37.9 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EGF83610.1 - 2.3e-07 30.8 0.0 8.2e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGF83610.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.6 1 1 0 1 1 1 0 Glutamine amidotransferase domain GCV_H PF01597.19 EGF83611.1 - 1.1e-45 154.5 1.5 1.3e-45 154.3 1.5 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EGF83611.1 - 0.0082 16.0 0.2 0.026 14.4 0.2 1.8 2 1 1 3 3 3 1 Biotin-requiring enzyme THF_DHG_CYH_C PF02882.19 EGF83611.1 - 0.032 13.6 1.2 0.79 9.0 0.1 2.6 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1771 PF08590.10 EGF83612.1 - 2e-16 60.1 3.8 3.4e-16 59.4 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGF83612.1 - 5.7e-08 33.0 0.1 5.3e-07 29.9 0.1 2.5 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 EGF83612.1 - 0.00045 20.2 5.3 0.00045 20.2 5.3 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGF83612.1 - 0.00055 19.7 3.3 0.00055 19.7 3.3 2.8 2 1 0 2 2 2 1 CCCH-type zinc finger CUE PF02845.16 EGF83612.1 - 0.0017 18.0 0.1 0.0054 16.4 0.1 1.9 1 0 0 1 1 1 1 CUE domain zf-CCCH PF00642.24 EGF83612.1 - 0.0022 17.9 9.7 0.0034 17.2 1.0 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGF83612.1 - 0.0027 17.9 4.2 0.0063 16.7 4.2 1.6 1 0 0 1 1 1 1 Zinc-finger containing family YmdB PF13277.6 EGF83612.1 - 0.0036 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 YmdB-like protein Torus PF16131.5 EGF83612.1 - 0.019 15.7 7.9 0.067 13.9 1.5 2.7 1 1 1 2 2 2 0 Torus domain HTH_1 PF00126.27 EGF83612.1 - 0.12 12.4 0.3 0.32 11.0 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family zf-CCCH_2 PF14608.6 EGF83612.1 - 0.37 11.3 12.4 1.4 9.5 1.9 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 EGF83613.1 - 1.1e-62 211.8 0.1 2.2e-42 145.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83613.1 - 2.5e-27 95.8 0.1 3.9e-19 69.0 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF83613.1 - 0.00015 20.9 0.2 0.00023 20.3 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGF83613.1 - 0.00018 21.5 0.3 0.031 14.2 0.2 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGF83613.1 - 0.00071 19.0 0.1 0.0018 17.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGF83613.1 - 0.0014 18.1 0.2 0.0097 15.3 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGF83613.1 - 0.1 11.6 0.5 0.2 10.7 0.2 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 EGF83613.1 - 0.11 13.2 0.1 0.38 11.5 0.1 2.0 1 1 0 1 1 1 0 Protein kinase C terminal domain RIO1 PF01163.22 EGF83613.1 - 0.12 11.9 0.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Tetraspanin PF00335.20 EGF83614.1 - 1.5e-13 51.0 5.9 2e-13 50.6 5.9 1.2 1 0 0 1 1 1 1 Tetraspanin family STE3 PF02076.15 EGF83614.1 - 0.016 14.4 0.1 0.016 14.4 0.1 2.9 3 0 0 3 3 3 0 Pheromone A receptor TMEM219 PF14940.6 EGF83614.1 - 0.034 13.7 1.2 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 Transmembrane 219 DUF2157 PF09925.9 EGF83614.1 - 0.13 12.0 2.5 0.12 12.2 0.2 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Sigma_reg_N PF13800.6 EGF83614.1 - 0.61 10.4 2.9 12 6.3 0.2 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Lysis_col PF02402.16 EGF83614.1 - 1.7 8.4 4.5 1.7 8.4 0.4 2.4 2 0 0 2 2 2 0 Lysis protein PhyH PF05721.13 EGF83615.1 - 1e-55 189.3 0.0 1.1e-55 189.1 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EGF83615.1 - 0.079 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Met_10 PF02475.16 EGF83617.1 - 6.2e-71 238.3 0.0 8.3e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EGF83617.1 - 0.0082 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 EGF83617.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SHIPPO-rpt PF07004.12 EGF83618.1 - 8.4e-19 67.5 31.4 0.00026 21.7 1.0 6.4 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Cpn60_TCP1 PF00118.24 EGF83619.1 - 3.3e-159 530.7 5.7 3.7e-159 530.5 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EGF83619.1 - 0.055 13.7 3.6 34 4.6 0.0 3.7 3 0 0 3 3 3 0 Enolase, N-terminal domain CPT PF07931.12 EGF83619.1 - 0.12 12.2 1.4 1.3 8.9 0.1 2.9 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein UQ_con PF00179.26 EGF83620.1 - 1.4e-16 60.4 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGF83620.1 - 0.0012 19.1 0.1 0.0015 18.8 0.1 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EGF83620.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 UEV domain Ank_4 PF13637.6 EGF83621.1 - 3.3e-16 59.4 0.1 4.3e-08 33.6 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF83621.1 - 7e-14 51.7 0.2 7.5e-06 26.1 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF83621.1 - 7.9e-14 52.0 0.1 1e-05 26.0 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGF83621.1 - 5.1e-11 42.5 3.4 9.6e-05 22.7 0.2 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGF83621.1 - 3.6e-09 36.1 2.3 0.00025 21.3 0.2 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EGF83622.1 - 2.9e-12 47.0 0.4 2.3e-07 31.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGF83622.1 - 1.4e-11 44.6 0.1 2.8e-07 31.0 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGF83622.1 - 1.6e-09 37.8 0.1 8.3e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGF83622.1 - 1.3e-08 34.9 0.1 6.8e-05 23.1 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGF83622.1 - 4.9e-07 29.5 0.0 0.0017 18.7 0.0 3.9 2 0 0 2 2 2 2 Ankyrin repeat Tropomyosin PF00261.20 EGF83622.1 - 0.088 12.2 16.4 0.22 10.9 0.9 3.3 4 0 0 4 4 4 0 Tropomyosin DUF948 PF06103.11 EGF83622.1 - 2.7 8.3 4.4 22 5.4 0.1 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.9 EGF83623.1 - 8e-20 71.1 0.1 1.2e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein O Med13_C PF06333.12 EGF83623.1 - 0.2 10.9 4.6 0.28 10.4 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain tRNA_U5-meth_tr PF05958.11 EGF83624.1 - 3e-10 39.6 2.0 8.9e-09 34.8 0.3 3.0 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGF83624.1 - 1.6e-08 34.5 0.2 5.6e-08 32.7 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF83624.1 - 1e-07 32.6 0.7 9.2e-07 29.5 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGF83624.1 - 1.6e-05 24.6 0.4 2.9e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EGF83624.1 - 2.6e-05 23.8 1.3 5.2e-05 22.8 0.3 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EGF83624.1 - 6e-05 22.7 0.1 0.00014 21.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain RRM_1 PF00076.22 EGF83624.1 - 0.00029 20.6 0.0 0.00067 19.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_11 PF08241.12 EGF83624.1 - 0.0051 17.4 0.1 0.023 15.3 0.1 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF83624.1 - 0.008 15.5 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGF83624.1 - 0.037 13.4 0.5 0.037 13.4 0.5 2.6 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EGF83624.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGF83624.1 - 0.12 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FinO_N PF12602.8 EGF83624.1 - 5.6 7.4 10.1 13 6.2 3.9 2.8 2 0 0 2 2 2 0 Fertility inhibition protein N terminal Radical_SAM PF04055.21 EGF83625.1 - 1.5e-18 67.8 0.1 2.4e-18 67.0 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EGF83625.1 - 2.2e-16 59.7 0.0 5.6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EGF83625.1 - 2.9e-07 30.4 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 EGF83625.1 - 0.11 12.7 0.0 1.1 9.5 0.0 2.6 1 1 0 1 1 1 0 TRAM domain Tristanin_u2 PF16638.5 EGF83626.1 - 0.0028 18.5 0.7 0.0032 18.3 0.7 1.2 1 0 0 1 1 1 1 Unstructured region on methyltransferase between zinc-fingers ABC_tran PF00005.27 EGF83627.1 - 2.3e-45 154.5 0.0 9e-22 78.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGF83627.1 - 1.9e-21 75.9 0.3 1.9e-21 75.9 0.3 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGF83627.1 - 6.9e-13 48.5 0.1 5.5e-05 22.7 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF83627.1 - 1e-12 48.5 1.0 0.0018 18.1 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF83627.1 - 9e-08 31.7 0.1 0.0055 16.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF83627.1 - 2.3e-07 30.9 0.1 0.034 14.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EGF83627.1 - 2.9e-07 30.6 0.8 0.014 15.1 0.4 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGF83627.1 - 3.9e-07 30.1 0.3 0.022 14.7 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGF83627.1 - 2.9e-06 27.9 8.7 0.085 13.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EGF83627.1 - 3.4e-06 27.5 0.3 0.096 13.1 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGF83627.1 - 1.6e-05 25.1 0.9 0.15 12.2 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGF83627.1 - 1.7e-05 25.1 0.4 0.26 11.6 0.0 3.0 2 2 0 2 2 2 2 AAA domain NACHT PF05729.12 EGF83627.1 - 4.8e-05 23.3 0.0 0.082 12.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 EGF83627.1 - 4.9e-05 23.1 0.1 0.29 10.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGF83627.1 - 0.00013 22.0 0.1 0.072 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGF83627.1 - 0.00021 21.8 0.1 1.2 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGF83627.1 - 0.00022 21.5 0.9 0.57 10.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EGF83627.1 - 0.00036 21.0 0.0 1 9.8 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EGF83627.1 - 0.00064 19.1 0.1 0.19 11.0 0.1 2.2 2 0 0 2 2 2 1 Septin NB-ARC PF00931.22 EGF83627.1 - 0.00074 18.8 0.1 0.12 11.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 EGF83627.1 - 0.00076 19.6 3.5 0.33 11.0 0.0 3.0 3 1 0 3 3 3 1 Dynamin family DUF815 PF05673.13 EGF83627.1 - 0.0016 17.6 0.1 0.45 9.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EGF83627.1 - 0.0019 18.1 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 NTPase Seryl_tRNA_N PF02403.22 EGF83627.1 - 0.0019 18.4 4.3 0.0019 18.4 4.3 2.0 2 0 0 2 2 1 1 Seryl-tRNA synthetase N-terminal domain AAA_25 PF13481.6 EGF83627.1 - 0.0022 17.6 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EGF83627.1 - 0.0022 18.2 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 EGF83627.1 - 0.0024 17.5 0.1 1.1 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGF83627.1 - 0.0027 18.1 0.0 3.6 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 EGF83627.1 - 0.0039 16.9 0.0 0.98 9.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGF83627.1 - 0.0061 16.3 0.0 6.9 6.4 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein MeaB PF03308.16 EGF83627.1 - 0.0068 15.4 0.0 2.8 6.8 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EGF83627.1 - 0.0068 15.9 0.1 4.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 EGF83627.1 - 0.0091 15.9 0.4 0.23 11.3 0.3 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EGF83627.1 - 0.014 15.4 0.1 7.7 6.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EGF83627.1 - 0.021 14.9 4.7 0.58 10.2 0.0 3.2 3 1 0 3 3 2 0 Helicase HerA, central domain cobW PF02492.19 EGF83627.1 - 0.026 14.1 0.2 5.2 6.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EGF83627.1 - 0.027 14.0 0.1 5.8 6.4 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGF83627.1 - 0.039 13.7 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGF83627.1 - 0.11 12.5 0.0 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EGF83627.1 - 0.15 12.3 0.4 2.5 8.4 0.2 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 EGF83627.1 - 0.15 11.8 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 EGF83627.1 - 0.19 11.1 1.7 9.3 5.5 0.0 3.1 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA_13 PF13166.6 EGF83627.1 - 0.3 9.7 4.9 2.1 6.9 0.5 2.6 3 1 0 3 3 3 0 AAA domain DUF2312 PF10073.9 EGF83627.1 - 0.4 10.4 3.7 4.5 7.0 0.1 2.8 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Ribosomal_L5e PF17144.4 EGF83628.1 - 6e-84 280.0 0.1 1.4e-83 278.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGF83628.1 - 1.2e-30 106.2 5.0 1.2e-30 106.2 5.0 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Pec_lyase_N PF04431.13 EGF83628.1 - 0.91 9.8 5.2 5.4 7.3 0.2 2.6 1 1 1 2 2 2 0 Pectate lyase, N terminus Glyco_hydro_31 PF01055.26 EGF83629.1 - 4.8e-143 477.5 5.1 6.5e-143 477.1 5.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGF83629.1 - 4.1e-23 81.5 0.1 1.1e-21 76.9 0.0 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EGF83629.1 - 5.8e-06 26.5 0.1 1.6e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) ABC_membrane PF00664.23 EGF83631.1 - 8.7e-117 389.6 30.9 2.1e-64 217.8 7.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF83631.1 - 4.8e-67 224.7 0.0 1.3e-33 116.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF83631.1 - 6.6e-16 58.4 0.0 4.7e-06 26.2 0.0 3.7 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGF83631.1 - 5.2e-08 32.1 1.9 0.0056 15.5 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EGF83631.1 - 4.4e-06 26.7 0.0 0.092 12.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGF83631.1 - 1.1e-05 25.8 1.3 0.35 11.1 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGF83631.1 - 6e-05 23.5 4.2 0.065 13.6 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGF83631.1 - 0.00022 20.9 5.4 0.072 12.8 0.3 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGF83631.1 - 0.00026 21.2 3.4 0.74 10.1 0.3 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 EGF83631.1 - 0.00029 20.1 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 EGF83631.1 - 0.00042 19.7 1.9 0.096 12.0 0.0 3.6 4 0 0 4 4 4 1 Zeta toxin APS_kinase PF01583.20 EGF83631.1 - 0.00051 20.0 0.3 0.59 10.0 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_30 PF13604.6 EGF83631.1 - 0.0011 18.7 4.3 0.79 9.4 0.4 3.6 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 EGF83631.1 - 0.0023 18.1 2.5 0.038 14.1 0.2 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_15 PF13175.6 EGF83631.1 - 0.0025 17.6 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGF83631.1 - 0.013 15.3 1.1 14 5.4 0.1 3.7 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGF83631.1 - 0.015 14.9 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EGF83631.1 - 0.015 14.5 0.6 1.9 7.6 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EGF83631.1 - 0.02 15.1 0.2 5.4 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGF83631.1 - 0.022 15.3 0.0 6.6 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGF83631.1 - 0.023 14.8 0.4 5.8 7.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EGF83631.1 - 0.024 14.6 0.4 5.7 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGF83631.1 - 0.036 14.5 4.6 6.9 7.1 1.2 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGF83631.1 - 0.068 12.3 0.0 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 EGF83631.1 - 0.069 12.9 0.3 7.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EGF83631.1 - 0.071 12.7 6.3 3.8 7.0 0.1 3.5 4 0 0 4 4 4 0 AAA domain F1F0-ATPsyn_F PF10791.9 EGF83631.1 - 0.076 13.5 0.0 28 5.3 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Rad17 PF03215.15 EGF83631.1 - 0.077 12.9 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGF83631.1 - 0.083 13.3 0.0 26 5.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EGF83631.1 - 0.1 13.1 1.1 13 6.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Abhydrolase_2 PF02230.16 EGF83631.1 - 0.14 11.9 0.4 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AAA_24 PF13479.6 EGF83631.1 - 0.15 11.7 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGF83631.1 - 0.19 12.0 0.9 15 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain GPDPase_memb PF10110.9 EGF83631.1 - 0.74 8.5 7.4 0.71 8.6 0.1 2.8 2 1 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Trp_oprn_chp PF09534.10 EGF83631.1 - 3 7.6 7.6 27 4.5 2.4 3.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ESF1 PF18209.1 EGF83632.1 - 2.2 8.3 15.4 0.31 11.0 8.5 2.4 2 0 0 2 2 2 0 Embryo surrounding factor 1 RhoGEF PF00621.20 EGF83633.1 - 3.8e-35 121.8 0.0 7.9e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 EGF83633.1 - 1.3e-10 41.3 0.0 2.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 EGF83633.1 - 9.6e-07 28.6 0.2 2.4e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF83633.1 - 0.00018 21.1 0.3 0.00041 20.0 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF83633.1 - 0.00058 19.4 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF3104 PF11302.8 EGF83633.1 - 0.09 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF3972 PF13118.6 EGF83633.1 - 0.23 11.9 1.2 0.58 10.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) VIT1 PF01988.19 EGF83634.1 - 2e-68 230.5 1.7 2.2e-68 230.4 1.7 1.0 1 0 0 1 1 1 1 VIT family VIT1 PF01988.19 EGF83635.1 - 6.1e-61 206.0 1.6 8.3e-61 205.6 1.6 1.2 1 0 0 1 1 1 1 VIT family GEMIN8 PF15348.6 EGF83638.1 - 1.3e-06 28.9 11.8 2.5e-05 24.7 11.8 2.2 1 1 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Caudo_TAP PF02413.17 EGF83638.1 - 0.0026 17.9 0.4 0.0041 17.3 0.4 1.3 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Arch_fla_DE PF04659.13 EGF83638.1 - 0.037 13.9 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 Archaeal flagella protein Peptidase_S49_N PF08496.10 EGF83638.1 - 0.29 11.2 2.5 0.43 10.6 2.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3807 PF12720.7 EGF83638.1 - 3.2 8.0 13.5 1.1e+02 3.0 13.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) zf-C2H2 PF00096.26 EGF83639.1 - 0.00049 20.4 17.8 0.013 15.9 0.9 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF83639.1 - 0.0068 17.2 17.2 0.19 12.6 0.9 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGF83639.1 - 0.019 15.1 1.0 0.019 15.1 1.0 2.7 2 1 1 3 3 3 0 Aberrant zinc-finger zf_ZIC PF18366.1 EGF83639.1 - 8.5 6.6 6.2 1.9 8.7 2.0 2.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain Glyco_hydro_26 PF02156.15 EGF83640.1 - 2e-07 30.8 1.9 2.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 EGF83640.1 - 0.48 10.0 2.0 0.44 10.1 0.6 1.7 2 0 0 2 2 2 0 EF hand Peptidase_M1 PF01433.20 EGF83642.1 - 2.5e-78 262.6 0.2 4e-78 261.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGF83642.1 - 1.5e-55 189.0 1.3 3.2e-55 187.9 1.3 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGF83642.1 - 1.4e-46 159.0 1.7 3e-46 157.9 1.7 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain UCH PF00443.29 EGF83643.1 - 4.2e-72 242.7 0.0 5.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF83643.1 - 7.3e-13 48.8 0.3 4.9e-11 42.8 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase VASt PF16016.5 EGF83644.1 - 3.4e-25 89.2 0.0 7.6e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGF83644.1 - 6.1e-16 58.3 0.1 2e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 GRAM domain Utp14 PF04615.13 EGF83645.1 - 6.4e-168 560.7 66.5 6.4e-168 560.7 66.5 2.5 1 1 1 2 2 2 1 Utp14 protein TMEM132D_C PF15706.5 EGF83646.1 - 0.12 12.1 0.3 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FAM72 PF14976.6 EGF83647.1 - 9.7e-49 165.2 4.1 1e-48 165.1 4.1 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 EGF83647.1 - 2.1 8.6 8.2 5.1 7.4 8.2 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.32 EGF83648.1 - 1.7e-14 53.9 3.8 0.0039 18.0 0.2 7.1 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83648.1 - 1.4e-06 28.5 0.0 0.019 15.3 0.0 4.9 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 EGF83648.1 - 0.0013 17.4 0.0 0.0024 16.6 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_Mid PF14783.6 EGF83648.1 - 0.004 17.2 0.0 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGF83648.1 - 0.062 12.6 0.1 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Lactonase PF10282.9 EGF83648.1 - 0.079 12.2 0.1 3.4 6.8 0.0 2.8 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 EGF83648.1 - 0.097 11.6 0.1 5.7 5.8 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 EGF83648.1 - 0.13 11.5 0.0 3 7.1 0.0 2.9 4 0 0 4 4 4 0 CPSF A subunit region CTD_bind PF04818.13 EGF83650.1 - 3.7e-11 43.7 0.1 9.9e-11 42.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EGF83650.1 - 0.026 14.5 0.3 0.081 12.9 0.3 1.8 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 AMP-binding PF00501.28 EGF83651.1 - 4.4e-70 236.4 0.0 6e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGF83651.1 - 2.4e-68 230.1 0.0 3.9e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 EGF83651.1 - 1.3e-12 47.2 0.3 1.8e-11 43.4 0.3 2.1 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EGF83651.1 - 9.1e-12 45.2 0.0 2.3e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGF83651.1 - 5.1e-09 35.9 0.0 1.2e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF83651.1 - 2e-06 27.1 0.0 5.4e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EGF83651.1 - 1.5e-05 25.9 0.0 4e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EGF83651.1 - 0.0049 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sulfotransfer_3 PF13469.6 EGF83651.1 - 0.17 12.3 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Nas2_N PF18265.1 EGF83652.1 - 0.083 12.8 2.2 0.24 11.3 0.8 2.6 2 0 0 2 2 2 0 Nas2 N_terminal domain zf_CCCH_4 PF18345.1 EGF83653.1 - 1.8e-12 46.8 27.2 2e-05 24.5 3.1 3.7 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH_4 PF18044.1 EGF83653.1 - 3.8e-09 36.1 16.6 8.8e-05 22.2 0.7 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 EGF83653.1 - 9.4e-09 35.0 11.4 0.00035 20.4 0.9 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGF83653.1 - 7.6e-08 33.0 11.9 0.0044 17.7 0.4 3.5 1 1 2 3 3 3 3 Torus domain zf-CCCH_3 PF15663.5 EGF83653.1 - 9e-05 22.7 7.8 0.0015 18.7 7.8 2.3 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGF83653.1 - 0.00026 21.3 30.0 0.0051 17.2 2.1 4.7 4 1 0 4 4 4 3 RNA-binding, Nab2-type zinc finger DUF1043 PF06295.12 EGF83654.1 - 0.0013 18.7 1.0 0.0079 16.2 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1043) THOC7 PF05615.13 EGF83654.1 - 0.0092 16.3 3.6 0.021 15.1 3.6 1.6 1 0 0 1 1 1 1 Tho complex subunit 7 DUF3847 PF12958.7 EGF83654.1 - 0.023 14.8 2.4 0.023 14.8 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF1676 PF07898.13 EGF83654.1 - 0.027 14.5 0.8 0.23 11.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DUF1664 PF07889.12 EGF83654.1 - 0.04 14.0 8.5 0.61 10.1 1.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EGF83654.1 - 0.092 12.9 6.0 0.44 10.7 2.3 2.2 1 1 1 2 2 2 0 Tropomyosin like Apolipoprotein PF01442.18 EGF83654.1 - 0.15 11.9 5.0 0.43 10.4 5.0 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain COG2 PF06148.11 EGF83654.1 - 0.15 12.1 6.9 2.1 8.4 0.2 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 EGF83654.1 - 0.37 9.7 7.7 1.7 7.5 2.3 2.1 1 1 1 2 2 2 0 Vps53-like, N-terminal DUF5082 PF16888.5 EGF83654.1 - 0.38 11.0 9.4 0.89 9.8 8.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4094 PF13334.6 EGF83654.1 - 0.43 11.0 4.4 0.65 10.5 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.9 EGF83654.1 - 0.56 10.5 6.7 5.4 7.4 3.0 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EGF83654.1 - 0.68 10.1 9.4 17 5.6 9.4 2.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EGF83654.1 - 0.84 8.5 8.7 2 7.2 8.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EGF83654.1 - 1.1 9.3 8.6 3.1 7.9 0.2 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4618 PF15397.6 EGF83654.1 - 2.1 7.7 9.7 0.42 10.0 6.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) XhlA PF10779.9 EGF83654.1 - 3 8.1 7.7 4.8 7.5 2.9 3.2 2 2 1 3 3 3 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 EGF83654.1 - 4.3 7.4 9.3 2.9 7.9 2.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 EGF83654.1 - 5.1 7.6 7.7 32 5.1 6.8 2.4 1 1 2 3 3 3 0 Protein of unknown function DUF16 Exo_endo_phos PF03372.23 EGF83655.1 - 2.4e-06 27.2 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Tenui_NCP PF04876.12 EGF83655.1 - 0.068 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Thioredoxin PF00085.20 EGF83656.1 - 7.7e-06 25.8 1.2 0.013 15.4 0.0 2.5 1 1 2 3 3 3 2 Thioredoxin Phage_tail_L PF05100.12 EGF83656.1 - 0.0019 17.5 0.1 0.0026 17.1 0.1 1.1 1 0 0 1 1 1 1 Phage minor tail protein L Thioredoxin_2 PF13098.6 EGF83656.1 - 0.12 12.9 1.3 2 8.9 0.9 2.2 1 1 1 2 2 2 0 Thioredoxin-like domain WD40 PF00400.32 EGF83657.1 - 7.4e-55 181.7 17.4 2e-09 37.9 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83657.1 - 1.2e-14 54.3 0.1 0.0051 17.1 0.0 6.7 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF83657.1 - 1.7e-06 27.2 1.0 0.2 10.5 0.0 5.2 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGF83657.1 - 0.0054 15.1 0.0 0.072 11.4 0.0 2.1 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EGF83657.1 - 0.073 12.4 0.0 2.4 7.4 0.0 2.8 3 1 0 3 3 3 0 WD40-like domain DnaJ_C PF01556.18 EGF83658.1 - 2.8e-39 134.6 0.2 3.6e-39 134.2 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGF83658.1 - 3.4e-21 75.1 2.5 5.8e-21 74.4 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EGF83658.1 - 0.18 11.8 0.0 0.56 10.2 0.0 1.9 1 0 0 1 1 1 0 A repeated domain in UCH-protein Peroxin-3 PF04882.12 EGF83659.1 - 3e-113 379.3 0.2 3.8e-112 375.7 0.2 1.9 1 1 0 1 1 1 1 Peroxin-3 3HCDH_N PF02737.18 EGF83660.1 - 2.2e-58 197.1 3.5 2.8e-58 196.8 3.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGF83660.1 - 4e-35 120.3 0.0 7.7e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGF83660.1 - 0.0068 16.0 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 EGF83660.1 - 0.0098 16.1 1.9 0.025 14.7 1.9 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGF83660.1 - 0.017 14.7 0.2 0.083 12.5 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 EGF83660.1 - 0.018 15.7 0.6 0.033 14.8 0.6 1.4 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 EGF83660.1 - 0.018 15.3 0.1 0.064 13.5 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 EGF83660.1 - 0.042 14.4 2.8 0.2 12.3 2.8 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EGF83660.1 - 0.063 13.5 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EGF83660.1 - 0.084 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FliX PF10768.9 EGF83660.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator LIM PF00412.22 EGF83661.1 - 1.8e-09 37.7 1.7 3.1e-09 36.9 1.7 1.4 1 0 0 1 1 1 1 LIM domain ANAPC4_WD40 PF12894.7 EGF83662.1 - 3.2e-11 43.4 0.1 0.0064 16.8 0.0 5.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF83662.1 - 3.5e-09 37.2 10.2 0.064 14.2 0.0 6.5 4 2 1 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 EGF83662.1 - 0.0026 17.1 2.2 0.41 9.9 0.0 2.8 2 1 0 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 EGF83662.1 - 0.0032 16.8 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.11 EGF83662.1 - 0.006 16.5 0.0 0.66 9.8 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 EGF83662.1 - 0.019 14.7 0.0 5.5 6.6 0.0 3.0 3 0 0 3 3 3 0 TUP1-like enhancer of split PQQ_3 PF13570.6 EGF83662.1 - 0.18 12.3 2.4 6.4 7.4 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain NMO PF03060.15 EGF83663.1 - 2.1e-59 201.6 2.9 8.9e-58 196.2 2.9 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGF83663.1 - 1.3e-10 40.9 0.3 1.4e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 EGF83663.1 - 0.0048 16.2 0.6 0.0092 15.3 0.6 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase NanE PF04131.14 EGF83663.1 - 0.13 11.4 0.1 0.13 11.4 0.1 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 EGF83663.1 - 0.2 10.7 2.2 0.36 9.8 2.2 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase RVP_2 PF08284.11 EGF83664.1 - 0.02 14.7 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease Cbl_N PF02262.16 EGF83664.1 - 2 8.4 9.9 0.49 10.4 0.3 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 ZapB PF06005.12 EGF83664.1 - 4.1 7.9 11.1 0.49 10.9 1.7 3.2 2 1 1 3 3 3 0 Cell division protein ZapB Choline_transpo PF04515.12 EGF83665.1 - 1.5e-88 297.2 36.5 1.5e-88 297.2 36.5 3.6 3 1 0 3 3 3 1 Plasma-membrane choline transporter AAA_33 PF13671.6 EGF83666.1 - 1.1e-09 38.6 0.0 1.5e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF83666.1 - 4e-06 27.4 0.2 1.9e-05 25.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EGF83666.1 - 0.00023 21.3 0.0 0.0004 20.5 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase NACHT PF05729.12 EGF83666.1 - 0.0026 17.7 1.1 0.004 17.1 0.3 1.7 2 1 0 2 2 2 1 NACHT domain dNK PF01712.19 EGF83666.1 - 0.0052 16.7 1.5 0.46 10.3 0.1 2.1 1 1 0 2 2 2 1 Deoxynucleoside kinase AAA_22 PF13401.6 EGF83666.1 - 0.0053 17.0 0.1 0.013 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF83666.1 - 0.0054 17.1 0.0 0.01 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGF83666.1 - 0.0064 16.2 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase CPT PF07931.12 EGF83666.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.3 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EGF83666.1 - 0.012 16.0 0.1 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGF83666.1 - 0.013 15.2 0.2 0.019 14.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGF83666.1 - 0.014 14.6 0.2 0.026 13.7 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 EGF83666.1 - 0.037 13.8 0.7 0.061 13.1 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGF83666.1 - 0.043 14.3 0.1 0.085 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter ATP_bind_2 PF03668.15 EGF83666.1 - 0.05 12.9 0.3 2.7 7.2 0.3 2.1 2 0 0 2 2 2 0 P-loop ATPase protein family DUF2075 PF09848.9 EGF83666.1 - 0.08 12.2 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 EGF83666.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 EGF83666.1 - 0.097 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGF83666.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 EGF83666.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGF83666.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGF83666.1 - 0.12 12.1 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 EGF83666.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 EGF83666.1 - 0.15 11.5 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EGF83666.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EGF83666.1 - 0.18 11.4 0.5 0.28 10.7 0.5 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_C PF00271.31 EGF83667.1 - 9.7e-19 67.8 0.0 1.1e-14 54.7 0.0 3.2 2 1 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EGF83667.1 - 1.4e-13 51.0 0.1 4.1e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGF83667.1 - 4.5e-09 36.9 6.0 4.5e-09 36.9 6.0 2.2 2 0 0 2 2 2 1 RecQ zinc-binding BRCA2 PF00634.18 EGF83667.1 - 0.055 13.2 0.9 0.21 11.3 0.2 2.2 2 0 0 2 2 2 0 BRCA2 repeat Ras PF00071.22 EGF83668.1 - 3.5e-62 208.8 0.2 4.3e-62 208.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF83668.1 - 1.1e-35 122.5 0.1 1.7e-35 121.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF83668.1 - 3.7e-14 52.6 0.0 4.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF83668.1 - 9.1e-07 29.0 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF83668.1 - 0.00012 21.6 0.0 0.00049 19.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGF83668.1 - 0.0002 21.3 0.0 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGF83668.1 - 0.00042 20.7 0.2 0.00096 19.6 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.12 EGF83668.1 - 0.00048 19.6 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EGF83668.1 - 0.00049 20.6 0.7 0.0094 16.5 0.1 2.4 1 1 1 2 2 2 1 ABC transporter AAA_7 PF12775.7 EGF83668.1 - 0.0035 16.9 0.1 0.11 12.1 0.0 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGF83668.1 - 0.0041 17.4 0.5 0.025 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 EGF83668.1 - 0.007 15.8 0.0 0.032 13.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein SRPRB PF09439.10 EGF83668.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 EGF83668.1 - 0.036 14.1 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGF83668.1 - 0.038 14.0 0.1 0.088 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 EGF83668.1 - 0.049 12.7 0.0 0.17 10.9 0.0 1.8 2 1 0 2 2 2 0 MCM P-loop domain AAA_21 PF13304.6 EGF83668.1 - 0.049 13.4 0.4 0.088 12.6 0.4 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGF83668.1 - 0.062 13.1 0.0 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGF83668.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EGF83668.1 - 0.064 13.0 0.5 0.11 12.2 0.0 1.8 2 1 0 2 2 1 0 AAA domain KAP_NTPase PF07693.14 EGF83668.1 - 0.071 12.3 0.0 0.27 10.4 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 EGF83668.1 - 0.096 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 EGF83668.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 EGF83668.1 - 0.12 12.6 0.5 0.41 10.9 0.0 2.3 2 1 0 2 2 1 0 AAA domain PPR_3 PF13812.6 EGF83669.1 - 1.6e-39 133.8 0.2 1e-09 38.3 0.0 8.3 5 2 3 8 8 8 8 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGF83669.1 - 2.9e-34 117.0 0.1 1.3e-06 28.5 0.0 8.8 6 2 2 9 9 9 6 PPR repeat family PPR PF01535.20 EGF83669.1 - 1.6e-25 87.5 12.6 0.0015 18.7 0.2 9.7 12 0 0 12 12 11 5 PPR repeat PPR_long PF17177.4 EGF83669.1 - 7.3e-23 81.1 2.1 2e-07 30.6 0.0 4.5 2 2 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGF83669.1 - 9.7e-16 57.2 0.2 0.0059 16.3 0.0 7.3 8 0 0 8 8 8 3 PPR repeat Vitellogenin_N PF01347.22 EGF83669.1 - 0.00057 18.4 2.2 0.14 10.5 0.3 2.3 2 0 0 2 2 2 2 Lipoprotein amino terminal region DUF3368 PF11848.8 EGF83669.1 - 0.0011 18.7 0.0 17 5.3 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3368) RPM2 PF08579.11 EGF83669.1 - 0.0013 19.1 1.1 4.5 7.7 0.0 4.8 3 1 1 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) rpo132 PF12415.8 EGF83669.1 - 0.083 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase LPD11 PF18824.1 EGF83669.1 - 0.085 12.9 0.1 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 Death PF00531.22 EGF83669.1 - 0.13 12.4 0.3 0.45 10.7 0.2 2.0 2 0 0 2 2 2 0 Death domain TPT PF03151.16 EGF83670.1 - 1e-19 71.0 21.1 1.3e-19 70.7 21.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGF83670.1 - 6.1e-08 32.9 13.8 6.1e-08 32.9 13.8 2.2 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 EGF83670.1 - 0.00013 21.3 23.0 0.00017 20.9 23.0 1.1 1 0 0 1 1 1 1 UAA transporter family CHD5 PF04420.14 EGF83671.1 - 9e-34 116.6 2.3 1e-33 116.4 2.3 1.0 1 0 0 1 1 1 1 CHD5-like protein FlxA PF14282.6 EGF83671.1 - 0.014 15.4 1.4 0.02 14.9 1.4 1.3 1 0 0 1 1 1 0 FlxA-like protein WD40 PF00400.32 EGF83672.1 - 1.7 9.7 11.3 32 5.6 0.0 5.3 4 2 0 4 4 4 0 WD domain, G-beta repeat TPR_2 PF07719.17 EGF83673.1 - 2.1e-06 27.4 0.4 0.046 13.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGF83673.1 - 2e-05 24.9 0.3 0.042 14.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF83673.1 - 5.5e-05 22.8 2.2 0.51 10.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF83673.1 - 0.00024 20.7 0.1 0.015 14.9 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EGF83673.1 - 0.002 18.7 0.3 5.6 7.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF83673.1 - 0.005 17.0 0.1 1.5 9.0 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF83673.1 - 0.02 14.9 0.1 6.9 7.0 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF83673.1 - 0.03 14.6 0.2 3 8.2 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGF83673.1 - 0.076 13.5 2.1 15 6.1 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 EGF83674.1 - 9.4e-28 95.9 0.1 8.8e-08 31.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF83674.1 - 2.3e-12 46.6 0.0 0.0029 17.4 0.0 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_5 PF13893.6 EGF83674.1 - 0.027 14.1 0.0 0.12 12.0 0.0 2.0 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF83674.1 - 0.033 14.3 0.0 19 5.5 0.0 3.6 3 1 0 3 3 3 0 RNA recognition motif RRM_Rrp7 PF17799.1 EGF83674.1 - 0.12 12.2 0.1 4 7.2 0.0 2.5 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain ParcG PF10274.9 EGF83675.1 - 3.2e-33 115.4 0.0 4.2e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein GHMP_kinases_N PF00288.26 EGF83678.1 - 1.7e-15 57.0 1.2 5.3e-15 55.4 1.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGF83678.1 - 1.1e-07 32.1 0.0 2.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal CTD PF12815.7 EGF83679.1 - 0.058 14.0 0.1 0.058 14.0 0.1 2.3 3 0 0 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 AAA PF00004.29 EGF83680.1 - 1.2e-73 245.7 0.0 2.9e-36 124.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF83680.1 - 6.5e-23 80.3 0.7 6.4e-12 45.1 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGF83680.1 - 6e-15 56.0 0.7 1.7e-05 25.2 0.0 4.5 2 2 3 5 5 5 2 AAA ATPase domain AAA_2 PF07724.14 EGF83680.1 - 8.4e-12 45.5 0.0 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGF83680.1 - 4.1e-11 43.0 0.1 0.00019 21.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGF83680.1 - 1.8e-09 37.5 0.0 0.0033 17.2 0.0 3.7 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF83680.1 - 8.4e-08 32.6 1.5 0.91 9.8 0.0 4.8 2 2 3 5 5 5 2 AAA domain AAA_33 PF13671.6 EGF83680.1 - 1.6e-07 31.6 0.0 0.02 15.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGF83680.1 - 7.9e-07 28.8 0.0 0.0033 17.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EGF83680.1 - 4.7e-06 26.7 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGF83680.1 - 1.3e-05 24.6 0.0 0.024 13.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_3 PF07726.11 EGF83680.1 - 1.4e-05 25.0 0.0 0.054 13.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGF83680.1 - 2.1e-05 24.5 0.1 0.023 14.6 0.0 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 EGF83680.1 - 2.2e-05 24.8 0.0 0.31 11.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 EGF83680.1 - 3.1e-05 24.0 0.1 0.073 13.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 EGF83680.1 - 9e-05 23.0 0.0 0.0098 16.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain MCM PF00493.23 EGF83680.1 - 0.00011 21.4 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_11 PF13086.6 EGF83680.1 - 0.00012 22.0 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGF83680.1 - 0.00031 20.4 0.5 0.097 12.2 0.0 3.2 2 2 1 3 3 3 1 AAA domain TsaE PF02367.17 EGF83680.1 - 0.00039 20.4 0.0 0.36 10.8 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EGF83680.1 - 0.00056 19.9 0.0 2.6 7.9 0.0 3.3 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EGF83680.1 - 0.0006 20.2 0.0 0.077 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGF83680.1 - 0.00087 18.5 0.0 1.6 7.9 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 EGF83680.1 - 0.00093 19.0 0.2 0.13 11.9 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EGF83680.1 - 0.0016 18.7 0.1 1.8 8.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGF83680.1 - 0.0016 18.2 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGF83680.1 - 0.0016 17.7 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EGF83680.1 - 0.0018 18.2 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 EGF83680.1 - 0.002 18.4 0.3 0.23 11.8 0.0 3.1 3 1 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EGF83680.1 - 0.0026 17.6 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EGF83680.1 - 0.0026 17.2 0.1 1.8 7.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGF83680.1 - 0.0026 17.5 0.0 3.7 7.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin PF02224.18 EGF83680.1 - 0.0038 17.0 0.1 1 9.1 0.1 2.6 3 0 0 3 3 2 1 Cytidylate kinase ATP_bind_1 PF03029.17 EGF83680.1 - 0.014 15.2 0.5 0.23 11.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EGF83680.1 - 0.017 14.3 0.0 5.4 6.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.19 EGF83680.1 - 0.037 13.6 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EGF83680.1 - 0.038 13.6 0.0 1.1 8.8 0.0 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EGF83680.1 - 0.049 13.4 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EGF83680.1 - 0.052 13.3 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGF83680.1 - 0.13 12.2 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 EGF83680.1 - 0.19 11.1 0.1 20 4.5 0.0 3.1 4 0 0 4 4 3 0 KaiC UCH PF00443.29 EGF83681.1 - 7.4e-52 176.4 0.3 8.3e-52 176.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF83681.1 - 7.3e-17 61.9 0.3 9.9e-17 61.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Furin-like_2 PF15913.5 EGF83681.1 - 0.044 14.0 0.8 0.098 12.8 0.8 1.6 1 1 0 1 1 1 0 Furin-like repeat, cysteine-rich I-EGF_1 PF18372.1 EGF83681.1 - 0.15 12.2 4.4 1.7 8.8 2.2 2.5 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Zn_ribbon_SprT PF17283.2 EGF83681.1 - 2.1 8.4 5.6 0.57 10.1 0.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Cofilin_ADF PF00241.20 EGF83682.1 - 1.2e-31 109.0 0.5 1.4e-17 63.6 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Monooxygenase_B PF04744.12 EGF83682.1 - 0.028 13.2 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 Monooxygenase subunit B protein zf-rbx1 PF12678.7 EGF83683.1 - 5.3e-10 39.4 3.2 8.2e-10 38.8 1.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGF83683.1 - 1.2e-08 35.1 4.4 1.2e-08 35.1 4.4 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EGF83683.1 - 1.8e-07 30.9 0.7 7.4e-07 28.9 0.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGF83683.1 - 7.3e-07 28.9 3.2 7.3e-07 28.9 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF83683.1 - 1.4e-06 28.2 0.6 5.9e-06 26.2 0.1 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF83683.1 - 5e-06 26.3 4.1 9.8e-05 22.1 1.1 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF83683.1 - 0.00018 21.4 0.4 0.00018 21.4 0.4 2.8 3 0 0 3 3 3 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGF83683.1 - 0.0002 20.9 2.1 0.00062 19.3 0.5 2.5 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGF83683.1 - 0.00049 19.9 1.1 0.00049 19.9 1.1 2.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGF83683.1 - 0.00077 19.5 1.4 0.0024 17.9 0.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGF83683.1 - 0.00096 19.3 0.8 0.0032 17.6 0.8 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGF83683.1 - 0.0017 18.1 1.0 0.0017 18.1 1.0 3.5 5 0 0 5 5 5 1 RING-like zinc finger Rtf2 PF04641.12 EGF83683.1 - 0.56 9.5 1.2 1.6 8.0 0.1 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 EGF83683.1 - 1.9 8.4 5.4 1.8 8.4 2.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain cNMP_binding PF00027.29 EGF83684.1 - 1.2e-17 63.7 0.1 5.7e-17 61.6 0.1 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain WD40 PF00400.32 EGF83685.1 - 2.5e-41 138.9 23.5 1.1e-06 29.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83685.1 - 2e-12 47.2 0.7 0.0013 19.0 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF83685.1 - 0.00016 21.1 0.8 7.1 5.9 0.1 3.5 2 1 0 3 3 3 3 WD40-like domain LisH_TPL PF17814.1 EGF83685.1 - 0.026 14.2 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 LisH-like dimerisation domain Nup160 PF11715.8 EGF83685.1 - 0.062 11.9 2.2 8.4 4.9 0.1 3.4 2 2 2 4 4 4 0 Nucleoporin Nup120/160 BPL_LplA_LipB PF03099.19 EGF83686.1 - 1.8e-14 53.7 0.0 2.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Asp PF00026.23 EGF83688.1 - 8.1e-14 51.8 0.0 1.1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF83688.1 - 1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Spt4 PF06093.13 EGF83689.1 - 0.51 10.5 1.8 3.9 7.6 0.0 3.0 4 0 0 4 4 4 0 Spt4/RpoE2 zinc finger WDCP PF15390.6 EGF83689.1 - 7.1 4.9 10.4 7.4 4.8 9.4 1.3 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Arm PF00514.23 EGF83692.1 - 0.00014 21.8 0.1 0.0021 18.0 0.0 2.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EGF83692.1 - 0.066 12.6 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5578) DUF4246 PF14033.6 EGF83693.1 - 6.6e-29 101.3 0.0 8.6e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) HJURP_C PF12347.8 EGF83695.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat AAA_14 PF13173.6 EGF83696.1 - 0.00023 21.2 0.0 0.97 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF4478 PF14793.6 EGF83696.1 - 0.13 12.2 0.2 3.8 7.4 0.1 2.9 3 0 0 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases zf-RING_7 PF02591.15 EGF83697.1 - 0.053 13.7 0.0 0.11 12.8 0.0 1.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain DUF5105 PF17118.5 EGF83701.1 - 0.03 14.1 1.3 0.065 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) DUF1275 PF06912.11 EGF83702.1 - 4e-10 39.9 9.2 5.2e-10 39.6 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1275 PF06912.11 EGF83703.1 - 6.7e-10 39.2 1.6 8.4e-10 38.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) GPS2_interact PF15784.5 EGF83704.1 - 0.016 15.6 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DASH_Dad2 PF08654.10 EGF83704.1 - 0.29 11.6 3.8 0.32 11.4 0.2 2.6 3 1 0 3 3 3 0 DASH complex subunit Dad2 TLE_N PF03920.15 EGF83704.1 - 0.48 10.5 2.7 20 5.3 0.1 2.2 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain WXG100 PF06013.12 EGF83704.1 - 0.58 10.4 3.9 6 7.2 0.5 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF1505 PF07403.11 EGF83706.1 - 0.035 14.3 1.5 0.06 13.5 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1505) Tom22 PF04281.13 EGF83706.1 - 0.14 11.9 4.5 0.066 13.0 1.9 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF4692 PF15763.5 EGF83706.1 - 0.69 10.4 5.4 0.16 12.4 1.9 1.6 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DNA_pol_delta_4 PF04081.13 EGF83706.1 - 0.88 9.9 3.6 0.56 10.6 0.8 2.0 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 Asp PF00026.23 EGF83710.1 - 3.3e-11 43.2 0.1 2.4e-10 40.4 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF83710.1 - 0.052 13.3 0.0 0.45 10.3 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Death_2 PF14786.6 EGF83713.1 - 0.085 12.8 3.2 0.18 11.7 0.1 2.5 2 1 0 2 2 2 0 Tube Death domain DUF1180 PF06679.12 EGF83714.1 - 1.7 9.0 6.5 2.9 8.3 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PA26 PF04636.13 EGF83714.1 - 10 4.9 12.3 0.71 8.7 2.7 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF4246 PF14033.6 EGF83715.1 - 7.5e-30 104.4 0.1 9.1e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arm PF00514.23 EGF83716.1 - 9.5e-05 22.3 0.0 0.0036 17.3 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 EGF83716.1 - 0.01 15.9 1.3 3 8.0 0.0 3.7 2 1 2 4 4 4 0 V-ATPase subunit H DUF5578 PF17741.1 EGF83716.1 - 0.025 14.0 0.1 0.064 12.7 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5578) WDCP PF15390.6 EGF83717.1 - 0.012 14.0 1.2 0.015 13.8 0.8 1.2 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Dynactin_p22 PF07426.11 EGF83717.1 - 0.1 12.5 1.0 0.66 9.8 0.2 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 Phe_tRNA-synt_N PF02912.18 EGF83717.1 - 0.93 9.5 3.8 0.28 11.2 0.3 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Asp PF00026.23 EGF83718.1 - 8.2e-14 51.7 0.1 1.3e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF83718.1 - 3.8e-05 23.5 0.1 0.00017 21.4 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal MFS_5 PF05631.14 EGF83719.1 - 7.1e-94 314.6 18.8 8.9e-94 314.3 18.8 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGF83719.1 - 1.8e-18 66.6 33.6 5.7e-18 65.0 33.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF83719.1 - 0.00012 21.1 4.7 0.00012 21.1 4.7 3.2 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EGF83719.1 - 0.0073 15.2 24.2 0.058 12.3 24.2 1.9 1 1 0 1 1 1 1 MFS_1 like family EVC2_like PF12297.8 EGF83719.1 - 0.21 10.3 0.3 0.5 9.0 0.3 1.6 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Arrestin_N PF00339.29 EGF83720.1 - 1.7e-08 34.6 0.0 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SH3_9 PF14604.6 EGF83720.1 - 1.7e-05 24.6 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Arrestin_C PF02752.22 EGF83720.1 - 0.0004 20.8 0.1 0.005 17.3 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SH3_2 PF07653.17 EGF83720.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF83720.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 SH3 domain IATP PF04568.12 EGF83721.1 - 1.2e-13 51.3 3.3 2.5e-07 31.0 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial ATPase inhibitor, IATP DUF1476 PF07345.11 EGF83721.1 - 1.6 9.1 6.9 1.7 9.1 1.2 2.8 2 1 1 3 3 3 0 ATPase inhibitor subunit zeta DHO_dh PF01180.21 EGF83722.1 - 1.2e-99 333.2 0.0 1.8e-99 332.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGF83722.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase MamL-1 PF09596.10 EGF83722.1 - 0.058 13.7 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 MamL-1 domain PcrB PF01884.17 EGF83722.1 - 0.57 9.6 2.1 11 5.4 0.1 2.2 1 1 1 2 2 2 0 PcrB family EpuA PF11772.8 EGF83722.1 - 0.93 9.2 4.6 1.3 8.7 3.3 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Radical_SAM PF04055.21 EGF83723.1 - 1.5e-13 51.5 0.0 2.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EGF83723.1 - 0.00087 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain YjcB PF15940.5 EGF83723.1 - 0.026 14.7 0.1 0.07 13.3 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function Gelsolin PF00626.22 EGF83724.1 - 1.3e-30 105.1 0.0 3e-07 30.2 0.0 5.7 5 0 0 5 5 5 4 Gelsolin repeat VHP PF02209.19 EGF83724.1 - 4.5e-12 45.8 0.1 9.2e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.29 EGF83724.1 - 2.7e-09 37.5 0.0 0.0023 18.4 0.0 4.0 3 0 0 3 3 3 2 PH domain WD40_4 PF16300.5 EGF83724.1 - 3.8e-05 23.5 0.1 8.2e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 EGF83724.1 - 0.0012 18.6 0.4 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40 PF00400.32 EGF83724.1 - 0.0092 16.8 3.5 1.5 9.8 0.3 4.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Kelch_5 PF13854.6 EGF83724.1 - 0.11 12.5 0.3 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Kelch motif PH_11 PF15413.6 EGF83724.1 - 0.11 12.9 0.0 29 5.1 0.0 3.1 2 0 0 2 2 2 0 Pleckstrin homology domain WD40 PF00400.32 EGF83725.1 - 2.9e-41 138.6 24.0 9.1e-07 29.5 0.8 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83725.1 - 8.6e-09 35.6 1.0 0.058 13.7 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EGF83725.1 - 4e-07 29.7 0.1 1e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGF83725.1 - 5.9e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EGF83725.1 - 9.7e-06 24.5 0.6 0.12 10.9 0.0 3.9 4 0 0 4 4 4 3 Nucleoporin Nup120/160 SWIRM PF04433.17 EGF83728.1 - 3.6e-08 33.6 0.0 6.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 SWIRM domain RSN1_7TM PF02714.15 EGF83729.1 - 7.5e-51 173.0 18.4 7.5e-51 173.0 18.4 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGF83729.1 - 5.6e-34 117.9 0.0 9e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGF83729.1 - 1.9e-30 105.7 0.4 1.9e-30 105.7 0.4 4.0 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport FRD2 PF03197.13 EGF83729.1 - 0.11 12.9 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage FRD2 protein GHMP_kinases_N PF00288.26 EGF83730.1 - 1.5e-12 47.6 1.0 3.7e-12 46.3 1.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGF83730.1 - 9.7e-05 22.7 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Cry1Ac_D5 PF17997.1 EGF83730.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 YBD PF17725.1 EGF83731.1 - 2.4e-10 40.6 0.5 3.4e-10 40.2 0.5 1.2 1 0 0 1 1 1 1 YAP binding domain Chorein_N PF12624.7 EGF83731.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 Ribosomal_S25 PF03297.15 EGF83732.1 - 3.5e-35 120.2 0.0 4e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_CodY PF08222.11 EGF83732.1 - 0.0023 17.4 0.4 0.0034 16.9 0.4 1.2 1 0 0 1 1 1 1 CodY helix-turn-helix domain MarR_2 PF12802.7 EGF83732.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 MarR family EAP30 PF04157.16 EGF83732.1 - 0.023 14.0 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_24 PF13412.6 EGF83732.1 - 0.044 13.4 0.3 0.061 12.9 0.3 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GntR PF00392.21 EGF83732.1 - 0.062 13.0 0.1 0.093 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ribosomal_L1 PF00687.21 EGF83733.1 - 3.3e-46 157.6 5.0 4.3e-46 157.2 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PhoU_div PF01865.16 EGF83733.1 - 0.031 13.6 0.2 0.48 9.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF47 F5_F8_type_C PF00754.25 EGF83735.1 - 0.00058 20.0 0.4 0.0011 19.1 0.1 1.6 2 0 0 2 2 2 1 F5/8 type C domain Polyketide_cyc PF03364.20 EGF83737.1 - 2.8e-17 63.1 0.0 3.2e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Myb_DNA-binding PF00249.31 EGF83738.1 - 7e-08 32.5 0.0 1.3e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF83738.1 - 0.00016 21.8 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lgl_C PF08596.10 EGF83739.1 - 2.9e-07 29.5 0.2 9.4e-06 24.6 0.0 3.2 2 2 1 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EGF83739.1 - 0.00081 19.6 0.2 13 6.2 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF83739.1 - 0.031 15.2 0.5 25 6.0 0.1 3.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Hira PF07569.11 EGF83739.1 - 0.42 10.3 4.8 3.4 7.3 0.2 3.5 4 0 0 4 4 4 0 TUP1-like enhancer of split Ank_5 PF13857.6 EGF83740.1 - 1.4e-15 57.1 0.0 3.9e-14 52.5 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGF83740.1 - 1.1e-10 41.8 0.1 3.9e-08 33.7 0.1 3.0 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGF83740.1 - 1.8e-10 41.3 0.0 3.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGF83740.1 - 9.2e-10 38.5 0.3 6.5e-05 23.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGF83740.1 - 1.9e-09 37.0 0.0 2.2e-06 27.6 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeat Ribosomal_S8e PF01201.22 EGF83741.1 - 3.5e-54 182.7 1.9 4.2e-54 182.4 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DnaJ PF00226.31 EGF83742.1 - 1.1e-24 86.3 4.2 2.8e-24 85.0 1.3 2.8 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 EGF83742.1 - 2.6e-24 84.0 13.1 1.3e-07 31.1 0.4 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGF83742.1 - 2.4e-18 64.7 10.8 0.00038 20.3 0.2 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGF83742.1 - 1.9e-12 46.3 10.2 2.8e-05 24.0 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGF83742.1 - 1.9e-10 41.1 6.0 0.1 13.1 0.0 5.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGF83742.1 - 2.6e-09 37.6 0.5 0.003 18.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGF83742.1 - 3.4e-09 36.2 9.5 0.0015 18.1 0.2 6.5 6 1 1 7 7 7 3 TPR repeat TPR_12 PF13424.6 EGF83742.1 - 3.6e-09 36.8 3.9 0.25 11.7 0.3 5.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF83742.1 - 5e-08 33.1 3.5 0.7 10.9 0.0 6.9 4 3 3 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF83742.1 - 9.7e-08 31.9 0.1 0.75 10.3 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGF83742.1 - 3.4e-07 29.8 2.2 0.52 10.5 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF83742.1 - 1.4e-05 25.1 0.5 0.018 15.1 0.1 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF83742.1 - 0.00043 20.1 2.7 0.14 12.1 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF83742.1 - 0.00054 20.0 2.2 0.38 10.9 0.0 3.9 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EGF83742.1 - 0.0022 18.5 4.4 14 6.6 1.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGF83742.1 - 0.0022 17.2 2.9 0.18 11.0 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF83742.1 - 0.0084 16.3 6.6 1.7 8.9 1.1 4.3 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF148 PF02520.17 EGF83742.1 - 0.04 14.0 1.0 0.34 11.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 NOG1_N PF17835.1 EGF83742.1 - 0.06 13.3 0.3 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 NOG1 N-terminal helical domain SHNi-TPR PF10516.9 EGF83742.1 - 0.094 12.2 0.3 9.8 5.7 0.0 3.3 4 0 0 4 4 4 0 SHNi-TPR PI3_PI4_kinase PF00454.27 EGF83743.1 - 4.6e-16 59.4 0.1 3.6e-11 43.4 0.1 3.2 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGF83743.1 - 0.0056 16.1 0.3 0.012 15.0 0.3 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) EMG1 PF03587.14 EGF83744.1 - 2.7e-81 271.9 0.1 3.2e-81 271.7 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ABC_membrane PF00664.23 EGF83745.1 - 1.6e-67 228.1 37.8 4e-37 128.3 13.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF83745.1 - 2e-55 187.0 0.1 8.3e-32 110.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF83745.1 - 6.5e-10 38.8 5.6 0.0051 16.3 0.1 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGF83745.1 - 8.3e-08 32.3 0.6 0.019 15.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGF83745.1 - 1.9e-07 31.6 0.0 0.021 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EGF83745.1 - 1.6e-06 28.3 3.0 0.00092 19.3 0.1 2.5 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EGF83745.1 - 1.9e-06 27.9 1.1 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGF83745.1 - 3.1e-06 26.8 0.2 0.062 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EGF83745.1 - 1.1e-05 25.0 0.1 0.024 14.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 EGF83745.1 - 3.6e-05 23.7 2.9 0.2 11.4 0.1 3.3 2 2 2 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGF83745.1 - 7.3e-05 21.9 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 EGF83745.1 - 0.0001 22.8 0.4 0.49 10.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGF83745.1 - 0.00019 21.7 0.6 0.75 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGF83745.1 - 0.00034 20.4 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGF83745.1 - 0.0006 19.8 0.2 0.3 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 EGF83745.1 - 0.0024 18.1 0.4 3.2 8.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EGF83745.1 - 0.0025 17.1 1.1 0.54 9.5 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 EGF83745.1 - 0.0067 16.0 1.6 0.73 9.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGF83745.1 - 0.0084 16.5 0.1 12 6.3 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EGF83745.1 - 0.0085 16.2 3.1 0.029 14.5 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain DUF815 PF05673.13 EGF83745.1 - 0.0091 15.2 0.2 0.53 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 EGF83745.1 - 0.01 15.2 0.4 1.3 8.3 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 EGF83745.1 - 0.011 16.1 0.1 4.6 7.7 0.0 3.0 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 EGF83745.1 - 0.012 14.7 0.4 0.45 9.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EGF83745.1 - 0.013 15.5 0.6 21 5.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGF83745.1 - 0.016 15.7 0.0 5.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGF83745.1 - 0.023 13.9 0.6 4.3 6.4 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 EGF83745.1 - 0.023 14.4 0.0 7.5 6.2 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 EGF83745.1 - 0.024 14.4 2.2 4.8 6.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_PrkA PF08298.11 EGF83745.1 - 0.046 12.6 0.5 4.2 6.2 0.1 2.3 2 0 0 2 2 2 0 PrkA AAA domain ATP_bind_1 PF03029.17 EGF83745.1 - 0.055 13.2 5.1 1.9 8.2 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 EGF83745.1 - 0.079 12.0 0.9 6.2 5.8 0.1 2.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 EGF83745.1 - 0.099 12.4 0.5 7 6.4 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 EGF83745.1 - 0.11 11.8 0.0 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 EGF83745.1 - 0.13 12.2 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EGF83745.1 - 0.16 12.0 0.0 27 4.8 0.0 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGF83745.1 - 0.41 10.8 1.7 24 5.1 0.2 2.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EGF83745.1 - 0.7 9.2 2.8 30 3.8 0.1 3.1 3 0 0 3 3 3 0 AIG1 family GTP_EFTU PF00009.27 EGF83747.1 - 2.7e-14 53.1 0.0 5.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Med9 PF07544.13 EGF83748.1 - 0.036 14.1 0.1 0.065 13.3 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CK_II_beta PF01214.18 EGF83749.1 - 2e-77 259.1 0.0 2.4e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Kinocilin PF15033.6 EGF83749.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinocilin protein Carla_C4 PF01623.17 EGF83749.1 - 0.25 11.3 1.6 0.84 9.6 0.1 2.1 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein Dus PF01207.17 EGF83750.1 - 6.6e-66 222.5 0.0 8.3e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ScsC_N PF18312.1 EGF83750.1 - 0.00085 19.1 0.1 0.0029 17.4 0.0 2.0 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain His_biosynth PF00977.21 EGF83750.1 - 0.0053 16.2 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 EGF83750.1 - 0.024 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase RabGAP-TBC PF00566.18 EGF83751.1 - 2.2e-25 89.6 1.5 3.5e-13 49.7 0.7 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain DDA1 PF10172.9 EGF83752.1 - 5.2e-18 65.1 0.7 6.5e-18 64.8 0.7 1.1 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase IL31 PF15209.6 EGF83752.1 - 0.00024 20.9 0.2 0.00027 20.7 0.2 1.1 1 0 0 1 1 1 1 Interleukin 31 GATA PF00320.27 EGF83753.1 - 1.2e-13 50.4 5.0 2.3e-13 49.5 5.0 1.5 1 0 0 1 1 1 1 GATA zinc finger SH3_9 PF14604.6 EGF83755.1 - 1.3e-09 37.8 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGF83755.1 - 8.6e-05 22.1 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain VHL PF01847.16 EGF83755.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 VHL beta domain TMEM154 PF15102.6 EGF83755.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family FMO-like PF00743.19 EGF83756.1 - 2.6e-127 425.5 0.0 2.9e-127 425.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGF83756.1 - 2.3e-22 79.7 0.0 1.7e-17 63.6 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGF83756.1 - 4.4e-17 62.3 0.0 5.1e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGF83756.1 - 8.4e-09 35.0 0.2 7.8e-07 28.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGF83756.1 - 6.7e-05 22.9 0.0 2 8.4 0.0 4.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGF83756.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGF83756.1 - 0.036 14.6 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGF83756.1 - 0.11 12.6 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EGF83756.1 - 0.22 10.7 0.2 0.59 9.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 EGF83757.1 - 2.2e-28 98.8 0.0 3.4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGF83757.1 - 1.5e-23 83.3 0.0 3.7e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal MFS_1 PF07690.16 EGF83758.1 - 1.3e-36 126.2 47.3 2.1e-33 115.7 24.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF83758.1 - 5e-11 42.1 26.6 1.8e-09 37.0 8.2 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EGF83758.1 - 0.22 10.3 19.0 0.018 13.9 3.7 2.9 2 1 0 2 2 2 0 MFS_1 like family DUF4668 PF15701.5 EGF83759.1 - 0.0088 15.9 0.5 0.011 15.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4668) DUF1682 PF07946.14 EGF83760.1 - 3.2e-52 177.7 12.3 5.3e-46 157.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1682) EF1_GNE PF00736.19 EGF83761.1 - 3.1e-34 117.0 1.1 4.2e-34 116.6 0.1 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGF83761.1 - 9.8e-14 51.5 7.1 9.8e-14 51.5 7.1 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region ANAPC15 PF15243.6 EGF83761.1 - 0.00047 20.5 0.2 0.46 10.9 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 15 GST_C_3 PF14497.6 EGF83761.1 - 0.0049 17.0 1.2 0.034 14.4 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MinC_N PF05209.13 EGF83761.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain GST_C_6 PF17171.4 EGF83761.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FYRN PF05964.14 EGF83762.1 - 7.3e-20 70.6 0.3 1.4e-19 69.7 0.3 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EGF83762.1 - 8.4e-19 67.5 0.0 1.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus TFIIS_C PF01096.18 EGF83763.1 - 3.3e-19 68.4 6.7 3.3e-19 68.4 6.7 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGF83763.1 - 1.5e-07 31.1 4.4 1.5e-07 31.1 4.4 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 EGF83763.1 - 0.0015 18.1 1.6 0.0031 17.1 1.6 1.6 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 EGF83763.1 - 0.028 14.4 2.7 0.028 14.4 2.7 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 EGF83763.1 - 0.038 13.8 6.3 0.2 11.5 1.1 2.6 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Nudix_N_2 PF14803.6 EGF83763.1 - 0.11 12.5 1.0 0.11 12.5 1.0 3.1 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_9 PF14369.6 EGF83763.1 - 0.28 11.5 8.7 3.1 8.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 EGF83763.1 - 0.46 10.0 13.3 0.52 9.8 0.0 3.5 4 0 0 4 4 4 0 zinc-ribbon domain CSN8_PSD8_EIF3K PF10075.9 EGF83764.1 - 2.5e-24 85.9 1.2 4.3e-24 85.1 1.2 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EGF83764.1 - 0.00021 21.7 2.5 0.00082 19.9 2.5 2.2 1 1 0 1 1 1 1 PCI domain Sdh5 PF03937.16 EGF83764.1 - 0.026 14.5 1.4 0.04 13.9 0.4 1.8 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase SID-1_RNA_chan PF13965.6 EGF83764.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAC3_GANP PF03399.16 EGF83764.1 - 0.12 11.7 0.7 0.17 11.2 0.7 1.2 1 0 0 1 1 1 0 SAC3/GANP family AAA_2 PF07724.14 EGF83765.1 - 2.9e-52 177.2 0.1 1.7e-49 168.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGF83765.1 - 5.3e-35 119.5 1.3 5.3e-35 119.5 1.3 2.6 2 1 1 3 3 2 1 AAA lid domain AAA PF00004.29 EGF83765.1 - 1.4e-23 83.8 2.6 2.2e-11 44.3 0.0 3.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGF83765.1 - 6.7e-23 80.6 0.9 2.6e-22 78.7 0.0 2.6 4 0 0 4 4 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGF83765.1 - 4e-17 62.5 0.1 6.2e-12 45.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF83765.1 - 2.1e-11 44.5 8.3 3e-05 24.5 0.1 4.8 4 2 1 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EGF83765.1 - 3e-10 40.1 0.0 9.6e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGF83765.1 - 2.7e-07 30.5 0.2 0.017 14.8 0.0 3.5 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.6 EGF83765.1 - 1.4e-06 28.6 7.9 0.023 15.0 0.0 5.0 4 3 0 4 4 4 2 AAA domain AAA_14 PF13173.6 EGF83765.1 - 2.4e-06 27.6 0.9 0.027 14.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EGF83765.1 - 2.7e-06 27.9 1.6 0.14 12.7 0.0 3.9 5 0 0 5 5 3 2 AAA domain AAA_24 PF13479.6 EGF83765.1 - 1.3e-05 25.0 0.0 0.054 13.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGF83765.1 - 1.5e-05 24.6 0.0 0.21 11.1 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGF83765.1 - 1.8e-05 24.2 0.0 0.44 9.9 0.0 3.4 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGF83765.1 - 4.8e-05 23.2 3.0 1.6 8.4 0.0 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGF83765.1 - 5.4e-05 23.5 0.0 0.8 10.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase DNA_pol3_delta2 PF13177.6 EGF83765.1 - 0.00025 20.9 0.2 3.5 7.4 0.0 4.0 4 1 0 4 4 4 1 DNA polymerase III, delta subunit ATPase_2 PF01637.18 EGF83765.1 - 0.0006 19.8 10.1 0.29 11.0 0.1 4.6 4 2 2 6 6 4 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGF83765.1 - 0.00062 19.4 0.0 1.8 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 EGF83765.1 - 0.0007 19.8 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EGF83765.1 - 0.00072 19.5 0.4 0.12 12.2 0.0 3.0 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 EGF83765.1 - 0.00079 19.4 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EGF83765.1 - 0.0012 18.8 0.5 1.6 8.6 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase ABC_tran PF00005.27 EGF83765.1 - 0.0045 17.5 0.8 1.4 9.4 0.0 3.4 3 0 0 3 3 3 1 ABC transporter SRP54 PF00448.22 EGF83765.1 - 0.0056 16.3 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 EGF83765.1 - 0.0075 16.0 0.1 2.1 8.1 0.0 2.8 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGF83765.1 - 0.0081 16.0 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EGF83765.1 - 0.0084 16.4 0.1 9.1 6.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain TIP49 PF06068.13 EGF83765.1 - 0.0097 15.1 3.8 3.5 6.7 0.3 3.2 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 EGF83765.1 - 0.011 15.9 0.0 9.7 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EGF83765.1 - 0.018 15.1 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 Torsin Zeta_toxin PF06414.12 EGF83765.1 - 0.022 14.1 0.4 1.7 7.9 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin AAA_30 PF13604.6 EGF83765.1 - 0.022 14.5 0.0 3.5 7.3 0.0 3.4 3 1 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGF83765.1 - 0.041 12.8 1.6 2.2 7.1 0.0 3.1 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 EGF83765.1 - 0.042 13.9 3.4 6.7 6.7 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain DUF815 PF05673.13 EGF83765.1 - 0.049 12.8 5.5 1.2 8.2 0.2 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGF83765.1 - 0.051 13.9 0.7 1.6 9.1 0.2 3.3 3 1 0 3 3 2 0 AAA domain PhoH PF02562.16 EGF83765.1 - 0.066 12.7 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 EGF83765.1 - 0.079 13.0 4.6 11 6.0 0.0 3.8 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EGF83765.1 - 0.11 12.4 0.1 6.5 6.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EGF83765.1 - 0.12 12.5 0.2 12 5.9 0.4 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 EGF83765.1 - 0.48 10.9 21.6 41 4.6 0.0 3.6 2 1 0 2 2 2 0 AAA domain Spt20 PF12090.8 EGF83766.1 - 0.0005 19.8 23.2 0.00065 19.4 23.2 1.1 1 0 0 1 1 1 1 Spt20 family Roughex PF06020.11 EGF83766.1 - 0.00053 19.2 5.6 0.00063 18.9 5.6 1.1 1 0 0 1 1 1 1 Drosophila roughex protein DDHD PF02862.17 EGF83766.1 - 0.0012 19.0 1.3 0.0013 19.0 1.3 1.1 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 EGF83766.1 - 0.002 18.2 13.7 0.0022 18.1 13.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGF83766.1 - 0.0077 15.0 2.4 0.0085 14.9 2.4 1.3 1 0 0 1 1 1 1 Presenilin TERB2 PF15101.6 EGF83766.1 - 0.0078 16.3 6.9 0.0099 16.0 6.9 1.1 1 0 0 1 1 1 1 Telomere-associated protein TERB2 POM121 PF15229.6 EGF83766.1 - 0.0084 15.8 9.0 0.012 15.3 9.0 1.2 1 0 0 1 1 1 1 POM121 family DUF3464 PF11947.8 EGF83766.1 - 0.014 15.2 2.5 0.021 14.6 2.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 EGF83766.1 - 0.015 15.5 3.2 0.019 15.1 3.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 EGF83766.1 - 0.015 16.0 5.4 0.015 16.0 5.4 1.6 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 EGF83766.1 - 0.021 15.7 6.9 0.036 15.0 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) BRF1 PF07741.13 EGF83766.1 - 0.024 15.0 3.5 0.036 14.4 3.5 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Band_3_cyto PF07565.13 EGF83766.1 - 0.032 14.1 3.4 0.039 13.7 3.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Podoplanin PF05808.11 EGF83766.1 - 0.045 13.9 0.8 0.059 13.5 0.8 1.2 1 0 0 1 1 1 0 Podoplanin SpoIIP PF07454.11 EGF83766.1 - 0.051 13.0 4.7 0.06 12.8 4.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1180 PF06679.12 EGF83766.1 - 0.054 13.9 0.5 0.067 13.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Maf1 PF09174.10 EGF83766.1 - 0.056 13.6 1.0 0.089 13.0 1.0 1.3 1 0 0 1 1 1 0 Maf1 regulator RP-C_C PF11800.8 EGF83766.1 - 0.064 13.3 4.9 0.086 12.9 4.9 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region eIF-3_zeta PF05091.12 EGF83766.1 - 0.1 11.6 6.7 0.12 11.3 6.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 EGF83766.1 - 0.1 12.6 1.0 0.1 12.6 1.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 EGF83766.1 - 0.12 12.1 2.8 0.14 11.9 2.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Connexin PF00029.19 EGF83766.1 - 0.12 12.1 1.0 0.16 11.7 1.0 1.2 1 0 0 1 1 1 0 Connexin DUF2722 PF10846.8 EGF83766.1 - 0.15 11.0 23.9 0.2 10.6 23.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Dynactin_p62 PF05502.13 EGF83766.1 - 0.17 10.6 7.0 0.23 10.2 7.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family CLN3 PF02487.17 EGF83766.1 - 0.2 10.7 0.8 0.23 10.5 0.8 1.2 1 0 0 1 1 1 0 CLN3 protein NARP1 PF12569.8 EGF83766.1 - 0.25 10.2 5.6 0.31 9.9 5.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM176 PF14851.6 EGF83766.1 - 0.29 10.8 3.3 0.53 9.9 3.3 1.4 1 0 0 1 1 1 0 FAM176 family Androgen_recep PF02166.16 EGF83766.1 - 0.36 9.6 19.0 0.56 9.0 19.0 1.3 1 0 0 1 1 1 0 Androgen receptor DUF4820 PF16091.5 EGF83766.1 - 0.36 10.2 6.3 0.48 9.8 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) V_ATPase_I PF01496.19 EGF83766.1 - 0.37 8.7 4.7 0.42 8.5 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SprA-related PF12118.8 EGF83766.1 - 0.4 9.8 19.2 0.52 9.4 19.2 1.1 1 0 0 1 1 1 0 SprA-related family UPF0560 PF10577.9 EGF83766.1 - 0.46 8.9 12.2 0.57 8.6 12.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.14 EGF83766.1 - 0.49 10.3 9.2 0.6 10.0 9.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PepSY_TM PF03929.16 EGF83766.1 - 0.54 9.9 2.6 0.89 9.2 2.6 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Mcm10 PF09332.11 EGF83766.1 - 0.55 9.6 10.8 0.76 9.1 10.8 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF4407 PF14362.6 EGF83766.1 - 0.69 9.2 8.1 1 8.7 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 EGF83766.1 - 1.1 8.6 13.4 1.5 8.2 13.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Activator_LAG-3 PF11498.8 EGF83766.1 - 1.2 8.0 24.4 1.5 7.8 24.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Paf1 PF03985.13 EGF83766.1 - 1.2 8.1 11.2 1.5 7.7 11.2 1.1 1 0 0 1 1 1 0 Paf1 DNApol_Exo PF18136.1 EGF83766.1 - 1.6 7.8 7.2 2.3 7.3 7.2 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DUF4175 PF13779.6 EGF83766.1 - 2.2 6.1 19.5 2.7 5.8 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Coilin_N PF15862.5 EGF83766.1 - 2.3 8.0 10.7 3.9 7.3 10.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus TMEM51 PF15345.6 EGF83766.1 - 4.1 7.2 10.5 6 6.6 10.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 RNA_pol_Rbc25 PF08292.12 EGF83766.1 - 5.2 7.3 11.1 3.5 7.9 9.0 1.7 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 Arrestin_C PF02752.22 EGF83767.1 - 3.7e-14 53.3 0.0 3e-10 40.7 0.1 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 EGF83767.1 - 0.0048 16.1 0.2 0.017 14.4 0.0 2.0 3 0 0 3 3 3 1 Rgp1 DUF2393 PF09624.10 EGF83767.1 - 0.056 13.4 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) rOmpB PF12334.8 EGF83767.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Arrestin_N PF00339.29 EGF83767.1 - 0.12 12.4 0.2 24 4.9 0.1 2.9 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain ArsA_ATPase PF02374.15 EGF83768.1 - 1.2e-108 362.9 0.1 1.4e-108 362.7 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGF83768.1 - 2.1e-13 50.6 0.1 6.2e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EGF83768.1 - 2.5e-12 47.0 0.0 3.5e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EGF83768.1 - 1.4e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EGF83768.1 - 2.8e-05 23.7 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EGF83768.1 - 0.00013 21.5 2.9 0.00028 20.4 0.4 2.2 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EGF83768.1 - 0.00029 20.5 0.2 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EGF83768.1 - 0.0047 16.2 0.1 0.0075 15.5 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGF83768.1 - 0.0063 16.9 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EGF83768.1 - 0.025 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EGF83768.1 - 0.082 13.3 0.0 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 EGF83768.1 - 0.085 12.4 0.6 0.22 11.1 0.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGF83768.1 - 0.19 12.3 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 EGF83769.1 - 2.2e-74 250.3 0.0 3.3e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGF83769.1 - 1.3e-16 60.9 0.1 4.9e-16 59.1 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EGF83769.1 - 2e-08 34.1 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 EGF83769.1 - 9.3e-08 32.3 0.3 3.4e-07 30.4 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF83769.1 - 3.5e-05 23.7 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 EGF83769.1 - 4.5e-05 23.3 1.8 0.00011 22.1 1.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGF83769.1 - 6.9e-05 22.6 2.1 0.00021 21.1 2.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWI2_SNF2 PF18766.1 EGF83769.1 - 0.00028 20.6 0.2 0.0037 17.0 0.0 2.6 2 1 0 2 2 2 1 SWI2/SNF2 ATPase zf-RING_2 PF13639.6 EGF83769.1 - 0.00056 20.2 2.6 0.0017 18.6 2.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGF83769.1 - 0.00069 19.6 1.3 0.0022 18.0 1.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF83769.1 - 0.0012 18.7 6.0 0.0025 17.6 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF83769.1 - 0.01 15.7 5.7 0.026 14.4 5.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGF83769.1 - 0.02 15.1 2.0 0.052 13.7 2.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGF83769.1 - 0.029 14.2 2.7 0.091 12.6 2.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mog1 PF04603.12 EGF83769.1 - 0.029 14.7 0.6 0.59 10.5 0.0 2.9 3 0 0 3 3 2 0 Ran-interacting Mog1 protein WW PF00397.26 EGF83769.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 WW domain zf-ANAPC11 PF12861.7 EGF83769.1 - 0.091 12.8 0.6 0.21 11.7 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGF83769.1 - 0.12 12.2 1.1 0.62 10.0 1.1 2.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cullin PF00888.22 EGF83770.1 - 2.9e-123 412.7 10.1 4.2e-123 412.1 10.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGF83770.1 - 7.9e-25 86.7 2.3 1.9e-24 85.4 1.7 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4070 PF13282.6 EGF83770.1 - 0.00021 21.5 0.2 0.00049 20.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) Ferrochelatase PF00762.19 EGF83771.1 - 6.8e-112 373.6 0.0 8e-112 373.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EGF83771.1 - 0.0035 17.6 0.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 CbiX SPRY PF00622.28 EGF83772.1 - 1.4e-20 73.6 1.3 1.1e-16 61.0 0.8 2.4 2 0 0 2 2 2 2 SPRY domain Noc2 PF03715.13 EGF83772.1 - 0.072 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Noc2p family Dynactin_p22 PF07426.11 EGF83773.1 - 2.9e-10 40.2 2.2 4.4e-10 39.7 2.2 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 Orthopox_A5L PF06193.11 EGF83773.1 - 0.037 13.5 2.5 0.045 13.2 1.7 1.4 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like Baculo_PEP_C PF04513.12 EGF83773.1 - 8.2 6.5 9.7 2 8.4 1.2 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rhomboid PF01694.22 EGF83774.1 - 2.2e-34 118.6 9.4 2.2e-34 118.6 9.4 2.2 2 0 0 2 2 2 1 Rhomboid family DUF4112 PF13430.6 EGF83774.1 - 0.078 13.3 0.6 0.21 11.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) WD40 PF00400.32 EGF83775.1 - 5.3e-07 30.2 15.6 2.5 9.1 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat IFT43 PF15305.6 EGF83776.1 - 3.1e-39 134.3 2.7 3.1e-39 134.3 2.7 1.8 2 0 0 2 2 2 1 Intraflagellar transport protein 43 SHS2_Rpb7-N PF03876.17 EGF83777.1 - 1.7e-12 47.6 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGF83777.1 - 5e-06 26.8 0.2 3.1e-05 24.2 0.2 2.1 1 1 0 1 1 1 1 S1 RNA binding domain Ribonuclease_3 PF00636.26 EGF83778.1 - 5.2e-36 123.4 0.1 8e-17 61.8 0.0 3.8 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF83778.1 - 2.1e-20 73.2 0.2 5.3e-08 33.1 0.0 4.4 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EGF83778.1 - 1.7e-09 37.7 0.0 2.6e-08 33.9 0.0 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.15 EGF83778.1 - 0.00022 21.3 0.4 0.00086 19.3 0.4 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAZ PF02170.22 EGF83778.1 - 0.00092 19.0 1.3 0.0026 17.6 0.2 2.4 2 0 0 2 2 2 1 PAZ domain Helicase_C PF00271.31 EGF83778.1 - 0.0016 18.7 0.1 0.031 14.6 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FUSC-like PF12805.7 EGF83778.1 - 0.0026 16.9 0.3 0.0052 15.9 0.3 1.4 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS dsrm PF00035.26 EGF83778.1 - 0.0039 17.9 0.0 0.027 15.2 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif KH_6 PF15985.5 EGF83779.1 - 8e-16 58.1 0.0 1.9e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 EGF83779.1 - 0.00069 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain NTPase_I-T PF01931.18 EGF83780.1 - 2.3e-51 173.8 0.0 2.6e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF4213 PF13938.6 EGF83780.1 - 0.031 14.5 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative heavy-metal chelation RhoGAP PF00620.27 EGF83782.1 - 4.7e-31 107.7 0.0 7.9e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EGF83782.1 - 0.00012 22.3 0.3 0.00034 20.8 0.1 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF1708 PF08101.11 EGF83782.1 - 0.0042 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) dCMP_cyt_deam_1 PF00383.23 EGF83783.1 - 2.8e-12 46.4 0.3 2.1e-11 43.6 0.3 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGF83783.1 - 1e-08 35.5 2.6 3.6e-05 24.0 0.2 2.8 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGF83783.1 - 0.0058 16.3 0.1 0.52 9.9 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF4869 PF16163.5 EGF83783.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) Inhibitor_I67 PF11405.8 EGF83783.1 - 0.19 12.0 0.5 0.46 10.8 0.1 1.8 2 0 0 2 2 2 0 Bromelain inhibitor VI IPPT PF01715.17 EGF83784.1 - 1.8e-58 198.1 0.0 3.1e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EGF83784.1 - 9.5e-07 28.4 0.1 2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 EGF83784.1 - 0.0014 18.8 0.3 0.051 13.7 0.0 2.8 2 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGF83784.1 - 0.013 16.1 0.1 0.14 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGF83784.1 - 0.026 14.9 0.3 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EGF83784.1 - 0.033 14.6 0.1 0.22 12.0 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGF83784.1 - 0.053 13.9 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EGF83784.1 - 0.13 12.7 0.1 0.4 11.2 0.0 1.8 2 1 0 2 2 2 0 ABC transporter DUF87 PF01935.17 EGF83784.1 - 2.9 7.9 6.0 0.91 9.6 1.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain tRNA-synt_1d PF00750.19 EGF83785.1 - 6.5e-94 314.7 1.1 8.6e-94 314.3 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGF83785.1 - 2.6e-20 72.7 0.3 6.8e-20 71.4 0.3 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGF83785.1 - 3.6e-05 24.3 0.0 0.0001 22.8 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C_3 PF14497.6 EGF83785.1 - 0.092 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RWD PF05773.22 EGF83786.1 - 7e-18 65.0 0.0 2.2e-17 63.4 0.0 1.8 1 1 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EGF83786.1 - 0.00012 22.5 0.1 0.0004 20.8 0.1 1.9 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 PQ-loop PF04193.14 EGF83787.1 - 5.7e-34 115.7 10.3 7.8e-18 64.0 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat Erv26 PF04148.13 EGF83787.1 - 0.0045 16.9 0.5 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Transmembrane adaptor Erv26 MtN3_slv PF03083.16 EGF83787.1 - 0.0087 16.1 2.9 0.044 13.8 0.3 2.5 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Pkinase PF00069.25 EGF83788.1 - 1.1e-62 211.8 0.0 7.9e-62 209.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83788.1 - 3.7e-29 101.8 0.1 2.4e-28 99.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGF83788.1 - 0.0033 16.8 0.4 0.0051 16.2 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family JIP_LZII PF16471.5 EGF83789.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Bin3 PF06859.12 EGF83790.1 - 1.5e-30 106.0 0.0 2.1e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 EGF83790.1 - 3.3e-07 31.0 0.0 1.9e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF83790.1 - 1.9e-06 27.8 0.0 0.00012 21.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF83790.1 - 4.2e-06 27.4 0.0 0.00066 20.3 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF83790.1 - 2.4e-05 24.2 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGF83790.1 - 0.0022 17.8 0.0 0.0073 16.1 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGF83790.1 - 0.0072 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGF83790.1 - 0.018 14.6 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EGF83790.1 - 0.025 15.2 0.0 0.76 10.5 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGF83790.1 - 0.06 12.6 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Kinesin PF00225.23 EGF83791.1 - 7e-59 199.4 0.0 8.8e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF83791.1 - 4.3e-23 81.9 0.0 6.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 EGF83792.1 - 5e-24 84.1 9.2 7.7e-07 29.7 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat F-box-like PF12937.7 EGF83792.1 - 6.4e-07 29.2 1.2 1.4e-06 28.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGF83792.1 - 5.6e-05 22.9 0.2 0.00017 21.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EGF83792.1 - 7.1e-05 21.6 1.2 0.0097 14.6 0.0 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGF83792.1 - 0.00015 22.0 0.1 0.017 15.4 0.0 3.6 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EGF83792.1 - 0.0072 15.3 1.3 0.74 8.7 0.0 3.4 2 1 2 4 4 4 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 EGF83792.1 - 0.024 14.2 0.0 0.33 10.5 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain DUF92 PF01940.16 EGF83793.1 - 7.8e-79 264.4 5.3 9.3e-79 264.2 5.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF4131 PF13567.6 EGF83793.1 - 0.019 14.7 1.4 2.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PMT_2 PF13231.6 EGF83793.1 - 0.037 14.3 0.6 0.037 14.3 0.6 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase PX PF00787.24 EGF83794.1 - 7.5e-14 51.7 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 PX domain V-SNARE_C PF12352.8 EGF83794.1 - 0.029 14.6 4.7 0.048 14.0 1.0 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus OKR_DC_1_N PF03709.15 EGF83795.1 - 0.086 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain TAF8_C PF10406.9 EGF83797.1 - 9e-12 45.4 0.5 9e-12 45.4 0.5 2.1 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EGF83797.1 - 1.1e-10 41.3 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EGF83797.1 - 0.0036 17.4 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Histone-fold protein E1-E2_ATPase PF00122.20 EGF83798.1 - 3.8e-50 169.9 0.1 3.8e-50 169.9 0.1 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGF83798.1 - 1.3e-42 145.6 3.8 1.3e-42 145.6 3.8 2.8 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGF83798.1 - 6.4e-23 82.1 0.0 3.4e-22 79.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF83798.1 - 2.6e-16 59.1 0.1 6.7e-16 57.7 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGF83798.1 - 4.7e-13 49.0 0.0 1.7e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGF83798.1 - 0.011 15.4 4.4 0.017 14.8 2.2 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGF83798.1 - 0.17 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PhoR PF11808.8 EGF83798.1 - 2.9 8.4 5.0 0.45 11.0 0.1 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR CAP PF00188.26 EGF83799.1 - 1.2e-13 52.0 1.0 2.2e-13 51.1 1.0 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Pro-rich PF15240.6 EGF83799.1 - 9.2e-05 22.8 46.8 0.00013 22.3 46.8 1.2 1 0 0 1 1 1 1 Proline-rich Cyclin PF08613.11 EGF83800.1 - 1.6e-12 48.1 0.0 1.6e-12 48.1 0.0 2.6 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGF83800.1 - 0.0049 16.6 1.3 0.0074 16.0 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Flg_hook PF02120.16 EGF83800.1 - 0.02 14.8 1.2 0.049 13.5 1.2 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK MGTL PF17059.5 EGF83801.1 - 0.038 13.8 3.5 0.038 13.8 3.5 2.0 1 1 1 2 2 2 0 MgtA leader peptide TPT PF03151.16 EGF83802.1 - 3.3e-68 230.2 27.6 3.7e-68 230.0 27.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGF83802.1 - 1.7e-16 60.7 31.2 1.9e-08 34.6 12.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGF83802.1 - 3.7e-06 26.4 25.8 8.2e-06 25.2 25.8 1.6 1 1 0 1 1 1 1 UAA transporter family Rax2 PF12768.7 EGF83802.1 - 0.018 14.5 0.1 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SLATT_5 PF18160.1 EGF83802.1 - 0.022 14.1 1.3 0.022 14.1 1.3 2.4 3 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 zf-UBR PF02207.20 EGF83804.1 - 2.2e-17 63.0 11.2 2.2e-17 63.0 11.2 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EGF83804.1 - 2.1e-08 33.8 0.0 7.7e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 EGF83804.1 - 0.0028 17.6 0.7 0.0028 17.6 0.7 3.4 4 1 1 5 5 5 1 zinc-RING finger domain ELL PF10390.9 EGF83804.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL TatD_DNase PF01026.21 EGF83805.1 - 4.4e-41 141.0 0.0 5.4e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Fe_hyd_lg_C PF02906.14 EGF83807.1 - 7.3e-66 222.3 0.0 1.7e-65 221.1 0.0 1.6 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 EGF83807.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_16 PF13484.6 EGF83807.1 - 5.1 8.1 5.5 1.1e+02 3.8 0.0 3.4 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain RabGAP-TBC PF00566.18 EGF83808.1 - 1.1e-09 38.2 6.6 1.5e-09 37.8 0.8 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain CYTL1 PF15153.6 EGF83808.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Cytokine-like protein 1 Mhr1 PF12829.7 EGF83808.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Biopterin_H PF00351.21 EGF83809.1 - 8.2e-161 534.6 0.0 9.9e-161 534.3 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 EGF83809.1 - 0.048 13.4 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 ACT domain Thymidylate_kin PF02223.17 EGF83810.1 - 3.3e-41 141.0 0.0 4.1e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 EGF83810.1 - 0.0043 17.6 0.0 0.0055 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EGF83810.1 - 0.0045 16.8 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 EGF83810.1 - 0.0098 16.1 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ribosomal_S7 PF00177.21 EGF83811.1 - 1.4e-32 112.3 1.3 1.8e-32 112.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CS PF04969.16 EGF83812.1 - 2.7e-19 69.9 0.1 1.3e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 CS domain SH3_1 PF00018.28 EGF83812.1 - 0.21 11.2 2.8 0.51 10.0 2.5 1.7 1 1 1 2 2 2 0 SH3 domain LRR_4 PF12799.7 EGF83813.1 - 3.1e-22 78.3 32.3 4.4e-06 26.9 0.7 9.1 6 2 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF83813.1 - 1.3e-17 63.2 31.2 1.9e-06 27.5 1.1 7.5 4 2 4 8 8 8 4 Leucine rich repeat LRR_9 PF14580.6 EGF83813.1 - 1.6e-05 24.5 10.1 0.27 10.7 0.4 4.7 2 2 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 EGF83813.1 - 0.0046 16.9 31.6 0.21 11.7 0.1 9.3 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 EGF83813.1 - 0.09 13.4 35.4 6.5 7.7 0.0 11.7 11 3 1 12 12 12 0 Leucine Rich Repeat PIP5K PF01504.18 EGF83815.1 - 1.1e-41 142.9 0.8 3.1e-33 115.2 0.5 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase LRR_8 PF13855.6 EGF83816.1 - 5.1e-38 128.6 29.2 3.5e-12 45.9 6.4 3.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGF83816.1 - 1.1e-22 79.8 32.6 5.9e-08 32.9 1.4 4.6 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF83816.1 - 9.3e-09 34.6 19.1 0.87 10.4 0.6 7.8 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_9 PF14580.6 EGF83816.1 - 8e-07 28.7 10.3 0.00068 19.2 1.4 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGF83816.1 - 0.00081 19.3 21.7 2.2 8.6 0.1 6.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_5 PF13306.6 EGF83816.1 - 0.0014 18.6 2.7 0.43 10.6 0.3 2.8 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) BRO1 PF03097.18 EGF83817.1 - 2.7e-106 355.7 10.9 2.7e-106 355.7 10.9 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGF83817.1 - 7.6e-72 242.1 10.2 1.4e-71 241.2 10.2 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV YkyA PF10368.9 EGF83817.1 - 0.13 11.9 10.1 0.65 9.6 3.4 2.8 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein FAM177 PF14774.6 EGF83818.1 - 7.2e-05 23.1 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 FAM177 family Pkinase PF00069.25 EGF83819.1 - 5e-66 222.8 0.0 5.9e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83819.1 - 9.7e-28 97.1 0.0 1.2e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF83819.1 - 2.6e-06 26.9 0.0 5.1e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGF83819.1 - 3.7e-05 22.7 0.0 6.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF83819.1 - 0.0016 17.8 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 EGF83819.1 - 0.0058 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain RIO1 PF01163.22 EGF83819.1 - 0.0093 15.6 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family 5-FTHF_cyc-lig PF01812.20 EGF83820.1 - 1.2e-45 155.7 0.0 1.4e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Actin PF00022.19 EGF83821.1 - 8.6e-24 83.9 0.1 3.3e-20 72.1 0.0 2.9 2 1 0 2 2 2 2 Actin PilM_2 PF11104.8 EGF83821.1 - 0.24 10.4 0.0 0.41 9.6 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; tRNA-synt_1 PF00133.22 EGF83822.1 - 8.7e-225 747.5 0.1 3.2e-224 745.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGF83822.1 - 1.1e-24 87.1 0.1 2.2e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGF83822.1 - 5e-15 55.1 0.4 8.3e-05 21.5 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGF83822.1 - 0.0041 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ATG27 PF09451.10 EGF83823.1 - 9.6e-22 78.1 0.0 1.2e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Dynein_light PF01221.18 EGF83824.1 - 5.4e-25 87.5 0.0 6.6e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 RTC PF01137.21 EGF83825.1 - 1.6e-55 187.7 0.0 1.9e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGF83825.1 - 5.2e-33 113.6 0.0 8.3e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain LisH_2 PF16045.5 EGF83826.1 - 9.2e-10 37.4 0.0 1.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 LisH Peptidase_A22B PF04258.13 EGF83827.1 - 2.5e-52 178.2 17.7 5.3e-33 114.7 11.6 3.0 2 1 0 2 2 2 2 Signal peptide peptidase EXS PF03124.14 EGF83828.1 - 3e-71 240.4 10.3 1.1e-70 238.7 10.3 1.9 1 1 0 1 1 1 1 EXS family CTNNB1_binding PF08347.11 EGF83828.1 - 0.084 13.1 0.8 0.18 12.0 0.8 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding GWT1 PF06423.12 EGF83828.1 - 1.4 9.0 4.0 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 GWT1 ABC_membrane PF00664.23 EGF83829.1 - 8.3e-56 189.6 38.1 7.1e-34 117.7 9.3 3.7 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGF83829.1 - 2.9e-44 150.9 0.0 4.5e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGF83829.1 - 5.9e-10 39.0 1.8 0.0068 15.9 0.3 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGF83829.1 - 1.5e-06 28.3 1.2 0.56 10.0 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGF83829.1 - 1.6e-06 28.1 0.1 0.023 14.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGF83829.1 - 1.7e-06 27.7 0.5 0.023 14.4 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGF83829.1 - 3.3e-05 23.9 0.3 0.3 11.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 EGF83829.1 - 0.00035 20.7 0.6 0.97 9.5 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EGF83829.1 - 0.0012 19.2 0.6 0.91 9.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EGF83829.1 - 0.0014 19.2 0.1 0.0014 19.2 0.1 3.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 EGF83829.1 - 0.0016 18.8 0.5 3.2 8.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EGF83829.1 - 0.0021 17.3 0.2 0.55 9.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 EGF83829.1 - 0.0023 18.0 0.9 0.16 12.1 0.0 2.8 3 0 0 3 3 2 1 Dynamin family T2SSE PF00437.20 EGF83829.1 - 0.0052 15.9 0.0 2.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGF83829.1 - 0.0084 15.5 0.5 1.5 8.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.6 EGF83829.1 - 0.028 14.6 0.1 2.3 8.5 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EGF83829.1 - 0.034 13.9 0.8 2 8.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGF83829.1 - 0.034 13.7 0.0 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGF83829.1 - 0.054 12.4 0.2 0.24 10.3 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 EGF83829.1 - 0.076 12.5 0.2 11 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGF83829.1 - 0.13 12.0 0.1 2.5 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EGF83829.1 - 0.13 12.4 0.2 7.8 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EGF83829.1 - 0.17 11.1 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Septin Kinesin PF00225.23 EGF83831.1 - 8.8e-101 337.1 0.0 9.9e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF83831.1 - 5.1e-18 65.4 0.1 1.2e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding T2SSE PF00437.20 EGF83831.1 - 0.034 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2408 PF10303.9 EGF83832.1 - 4.1e-28 98.6 4.3 3.2e-09 37.4 0.0 4.7 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) MAP65_ASE1 PF03999.12 EGF83832.1 - 0.002 16.9 3.4 0.023 13.4 0.3 2.3 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) APG6_N PF17675.1 EGF83832.1 - 0.006 17.1 2.5 0.92 10.0 0.0 2.7 2 0 0 2 2 2 1 Apg6 coiled-coil region TarH PF02203.15 EGF83832.1 - 0.02 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Translin PF01997.16 EGF83832.1 - 0.088 12.8 0.9 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Translin family RcpC PF16976.5 EGF83832.1 - 0.096 12.7 0.1 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB Mt_ATP-synt_D PF05873.12 EGF83832.1 - 0.26 11.1 2.3 0.35 10.7 0.2 2.2 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) CorA PF01544.18 EGF83832.1 - 1.2 8.4 5.3 2.3 7.5 1.0 2.9 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein PRKG1_interact PF15898.5 EGF83832.1 - 2.2 9.2 6.6 6.2 7.8 0.1 3.2 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain A_deaminase PF00962.22 EGF83834.1 - 3.2e-125 417.8 0.2 4.3e-125 417.4 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 EGF83835.1 - 1.7e-52 178.4 0.0 2.1e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83835.1 - 6.2e-30 104.3 0.0 7.7e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF83835.1 - 0.00068 19.0 0.9 0.0032 16.8 0.2 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGF83835.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF83835.1 - 0.032 14.2 0.0 0.079 12.9 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ral PF11058.8 EGF83835.1 - 0.036 13.6 0.1 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Antirestriction protein Ral FTA2 PF13095.6 EGF83835.1 - 0.079 12.6 0.3 1.6 8.3 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Inos-1-P_synth PF01658.17 EGF83835.1 - 0.16 12.2 0.4 0.26 11.5 0.4 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase N2227 PF07942.12 EGF83836.1 - 1.3e-23 83.5 0.2 9.4e-12 44.7 0.1 2.3 1 1 1 2 2 2 2 N2227-like protein B9-C2 PF07162.11 EGF83837.1 - 1.3e-27 97.1 0.0 2.5e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF3391 PF11871.8 EGF83837.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) zf-Tim10_DDP PF02953.15 EGF83838.1 - 1.2e-19 69.7 1.7 1.4e-19 69.4 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger N2227 PF07942.12 EGF83839.1 - 1.5e-85 286.7 0.0 2.3e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EGF83839.1 - 0.006 17.3 0.4 0.045 14.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF83839.1 - 0.035 14.7 0.0 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain LSM PF01423.22 EGF83840.1 - 8e-20 70.3 0.2 1.1e-19 69.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain Y_phosphatase2 PF03162.13 EGF83841.1 - 4.7e-53 179.2 0.0 5.2e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGF83841.1 - 4.8e-06 26.7 0.0 2.9e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGF83841.1 - 0.00042 20.1 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF83841.1 - 0.0072 15.9 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ras PF00071.22 EGF83842.1 - 4.8e-45 153.1 0.0 5.6e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF83842.1 - 5e-17 62.2 0.0 7.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF83842.1 - 2.6e-06 27.0 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGF83842.1 - 0.016 15.0 0.1 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGF83842.1 - 0.04 13.4 0.0 0.081 12.4 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Syncollin PF15138.6 EGF83842.1 - 0.042 14.1 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Syncollin RhoGAP PF00620.27 EGF83844.1 - 1.7e-41 141.5 0.1 3.4e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGF83844.1 - 1e-07 32.4 0.0 4.5e-07 30.3 0.0 2.2 1 0 0 1 1 1 1 PH domain PX PF00787.24 EGF83844.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 PX domain zf-AN1 PF01428.16 EGF83845.1 - 4.2e-06 26.8 1.6 4.2e-06 26.8 1.6 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger SapA PF02199.15 EGF83845.1 - 0.7 10.2 4.4 1.5 9.1 4.3 1.6 1 1 1 2 2 2 0 Saposin A-type domain SAGA-Tad1 PF12767.7 EGF83847.1 - 9.4e-32 110.6 0.0 5.4e-30 104.9 0.0 2.2 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Chitin_bind_1 PF00187.19 EGF83848.1 - 1.8e-56 188.3 211.4 4.9e-08 33.3 13.8 9.3 9 0 0 9 9 9 9 Chitin recognition protein SAGA-Tad1 PF12767.7 EGF83851.1 - 7.5e-32 111.0 0.0 4.5e-31 108.4 0.0 2.0 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Chitin_bind_1 PF00187.19 EGF83852.1 - 7.1e-55 183.2 208.4 1.7e-09 38.0 16.0 9.4 9 0 0 9 9 9 9 Chitin recognition protein Chitin_bind_1 PF00187.19 EGF83853.1 - 1.4e-28 99.0 120.9 2.1e-07 31.3 16.9 5.6 5 0 0 5 5 5 5 Chitin recognition protein RRM_1 PF00076.22 EGF83854.1 - 1.8e-08 34.1 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPTA PF01239.22 EGF83855.1 - 1.5e-40 135.8 25.0 1e-10 41.0 0.9 6.6 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat C12orf66_like PF09404.10 EGF83856.1 - 0.023 13.5 0.1 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 KICSTOR complex C12orf66 like DEAD PF00270.29 EGF83857.1 - 7.2e-43 146.4 0.0 1.7e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF83857.1 - 3.6e-21 75.6 0.0 2.2e-20 73.0 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGF83857.1 - 7.1e-16 58.2 0.5 1.6e-15 57.0 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGF83857.1 - 1.6e-05 25.0 0.0 7.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGF83857.1 - 0.0039 17.5 0.2 0.02 15.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain Peptidase_M1 PF01433.20 EGF83858.1 - 6.4e-35 120.7 0.8 1.1e-34 119.9 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 EGF83858.1 - 6.5e-12 45.7 3.2 0.00022 21.5 0.8 4.2 1 1 4 5 5 5 5 HEAT repeats Peptidase_M1_N PF17900.1 EGF83858.1 - 6e-11 42.9 0.2 2.5e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Pox_vIL-18BP PF05566.12 EGF83858.1 - 0.042 14.1 0.1 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Orthopoxvirus interleukin 18 binding protein SapB_1 PF05184.15 EGF83858.1 - 0.13 12.3 0.0 6.8 6.8 0.0 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 HEAT_PBS PF03130.16 EGF83858.1 - 0.18 12.6 4.6 27 5.8 1.6 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat LSM PF01423.22 EGF83859.1 - 0.00043 19.9 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 LSM domain DUF1840 PF08895.11 EGF83859.1 - 0.019 15.3 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) MAPEG PF01124.18 EGF83860.1 - 3e-17 62.8 0.4 3.9e-17 62.4 0.4 1.2 1 0 0 1 1 1 1 MAPEG family SNARE PF05739.19 EGF83861.1 - 0.0026 17.7 0.7 0.0072 16.3 0.7 1.8 1 0 0 1 1 1 1 SNARE domain V-SNARE_C PF12352.8 EGF83861.1 - 0.0071 16.6 2.5 0.02 15.1 0.5 2.7 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus phiKZ_IP PF12699.7 EGF83861.1 - 0.024 13.8 0.1 0.024 13.8 0.1 2.0 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins Laminin_I PF06008.14 EGF83861.1 - 0.039 13.7 4.9 0.19 11.4 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain I Syntaxin-6_N PF09177.11 EGF83861.1 - 0.06 13.9 6.7 0.68 10.5 2.3 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EGF83861.1 - 0.31 11.1 9.9 2.7 8.0 2.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 EGF83861.1 - 0.35 10.7 7.2 0.27 11.1 0.5 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SesA PF17107.5 EGF83861.1 - 0.65 10.2 4.3 0.72 10.0 1.5 2.4 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TMPIT PF07851.13 EGF83861.1 - 0.71 9.1 5.1 7.6 5.7 0.0 2.3 2 0 0 2 2 2 0 TMPIT-like protein AAA_13 PF13166.6 EGF83861.1 - 0.94 8.0 7.2 1.2 7.7 2.5 2.0 2 0 0 2 2 2 0 AAA domain DegS PF05384.11 EGF83861.1 - 1.3 8.5 8.8 0.2 11.1 0.2 3.0 2 1 2 4 4 4 0 Sensor protein DegS DUF883 PF05957.13 EGF83861.1 - 1.4 9.5 5.6 0.45 11.2 0.8 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Tox-REase-2 PF15646.6 EGF83861.1 - 2.5 8.3 6.1 4.3 7.5 0.1 3.0 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 2 GRP PF07172.11 EGF83861.1 - 2.6 8.8 7.9 0.71 10.6 0.8 2.4 2 0 0 2 2 2 0 Glycine rich protein family RmuC PF02646.16 EGF83861.1 - 3 6.9 8.2 8.8 5.4 0.4 2.9 3 0 0 3 3 3 0 RmuC family Fez1 PF06818.15 EGF83861.1 - 3.3 8.1 12.1 4.3 7.8 4.0 2.4 2 1 0 2 2 2 0 Fez1 BORCS8 PF10167.9 EGF83861.1 - 3.8 7.5 7.1 4.7 7.2 0.5 3.2 2 2 1 3 3 3 0 BLOC-1-related complex sub-unit 8 DUF16 PF01519.16 EGF83861.1 - 4.6 7.8 9.7 1.2 9.7 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Laminin_II PF06009.12 EGF83861.1 - 8 6.5 8.7 2.8 8.0 1.9 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF2203 PF09969.9 EGF83861.1 - 8.7 7.1 10.9 6.2 7.6 0.3 3.4 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Vma12 PF11712.8 EGF83862.1 - 2.4e-27 95.7 0.0 3.4e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP19 PF11022.8 EGF83863.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit K RRM_1 PF00076.22 EGF83864.1 - 4.7e-81 266.6 6.1 6.2e-18 64.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF83864.1 - 2.5e-05 24.1 0.0 1.7 8.5 0.0 4.7 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EGF83864.1 - 0.0019 18.2 1.2 16 5.6 0.1 4.5 5 0 0 5 5 5 2 RNA binding motif Sars6 PF12133.8 EGF83864.1 - 0.14 12.1 0.0 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus RRM_2 PF04059.12 EGF83864.1 - 0.14 12.4 0.1 3.1 8.1 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif 2 BORCS8 PF10167.9 EGF83865.1 - 2.4e-13 50.0 0.2 2.9e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 PuR_N PF09182.10 EGF83866.1 - 0.15 12.0 0.1 8 6.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal HSBP1 PF06825.12 EGF83866.1 - 0.27 11.1 1.4 0.64 9.9 1.4 1.6 1 1 0 1 1 1 0 Heat shock factor binding protein 1 DUF2400 PF09674.10 EGF83866.1 - 0.97 9.4 3.2 19 5.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Tub PF01167.18 EGF83868.1 - 3.1e-56 190.9 0.0 3.6e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Tub family WD40 PF00400.32 EGF83869.1 - 0.00017 22.3 2.3 0.0016 19.2 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Nbas_N PF15492.6 EGF83869.1 - 0.025 13.9 0.1 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PIP5K PF01504.18 EGF83871.1 - 2.4e-97 325.5 0.1 3.1e-97 325.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ASH PF15780.5 EGF83873.1 - 3e-11 43.4 10.3 0.012 15.8 0.1 9.2 11 0 0 11 11 11 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGF83873.1 - 2.9e-07 30.6 0.1 0.51 10.5 0.0 6.3 5 0 0 5 5 5 1 Flagellar-associated PapD-like DUF1573 PF07610.11 EGF83873.1 - 0.0015 18.6 5.2 33 4.6 0.0 6.3 6 0 0 6 6 6 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EGF83873.1 - 0.0029 17.8 3.7 62 3.9 0.0 7.5 7 1 1 8 8 8 0 Transmembrane protein 131-like GDE_N_bis PF14742.6 EGF83873.1 - 0.016 14.8 0.6 7 6.2 0.0 4.0 4 0 0 4 4 4 0 N-terminal domain of (some) glycogen debranching enzymes SWIB PF02201.18 EGF83874.1 - 9.1e-14 51.1 0.1 2.6e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Sof1 PF04158.14 EGF83875.1 - 2.6e-31 107.7 11.4 4.6e-31 106.9 11.4 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EGF83875.1 - 3.8e-24 84.5 8.4 0.0001 23.0 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 EGF83875.1 - 5.7e-05 23.1 0.5 0.028 14.3 0.1 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGF83875.1 - 8.7e-05 22.8 0.0 0.22 11.8 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Tombus_P33 PF08500.10 EGF83875.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Tombusvirus p33 PrmA PF06325.13 EGF83876.1 - 2.6e-05 23.8 0.1 4.8e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5_C PF17286.2 EGF83876.1 - 0.0015 18.4 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EGF83876.1 - 0.0033 18.1 0.0 0.018 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 EGF83876.1 - 0.0076 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 EGF83876.1 - 0.0079 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 EGF83876.1 - 0.023 14.5 0.0 0.09 12.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGF83876.1 - 0.086 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 EGF83876.1 - 0.13 12.9 0.0 0.51 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EGF83876.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UDPG_MGDP_dh_N PF03721.14 EGF83877.1 - 3.4e-64 215.9 0.0 6.1e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EGF83877.1 - 1.2e-34 118.8 0.1 3.1e-33 114.3 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EGF83877.1 - 3.4e-30 104.1 0.0 6.9e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 EGF83877.1 - 0.00063 19.9 0.0 0.021 15.0 0.0 2.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase OTCace PF00185.24 EGF83877.1 - 0.005 16.9 0.1 0.51 10.4 0.0 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain AlaDh_PNT_C PF01262.21 EGF83877.1 - 0.092 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EGF83877.1 - 0.099 12.9 0.1 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NT5C PF06941.12 EGF83877.1 - 0.13 12.1 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) BRE PF06113.12 EGF83879.1 - 5.9e-16 58.2 3.5 4.4e-15 55.3 3.5 2.0 1 1 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Glutaredoxin PF00462.24 EGF83880.1 - 1.4e-17 63.7 0.1 1.8e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EGF83880.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EGF83880.1 - 0.12 12.8 0.4 0.35 11.3 0.4 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 EGF83880.1 - 0.15 12.5 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Acetyltransf_1 PF00583.25 EGF83881.1 - 5.5e-21 75.0 0.0 6.7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGF83881.1 - 6.5e-14 52.0 0.0 8.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGF83881.1 - 1.7e-12 47.6 0.1 2.2e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGF83881.1 - 7.3e-10 38.7 0.1 1.4e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EGF83881.1 - 4e-06 26.6 0.0 7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGF83881.1 - 4.6e-06 27.3 0.0 5.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGF83881.1 - 5.5e-05 23.2 0.1 6.8e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGF83881.1 - 8.4e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EGF83881.1 - 0.051 13.0 0.2 0.11 12.0 0.2 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 EGF83881.1 - 0.069 13.3 0.1 0.08 13.1 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4783 PF16022.5 EGF83881.1 - 0.087 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) Lge1 PF11488.8 EGF83883.1 - 9.9 6.4 15.8 0.055 13.7 3.6 3.3 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 Aldedh PF00171.22 EGF83884.1 - 1.5e-133 445.7 0.1 1.7e-133 445.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGF83884.1 - 0.005 15.9 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Abhydrolase_3 PF07859.13 EGF83885.1 - 1.1e-30 107.1 0.0 5.7e-21 75.3 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold MAD PF05557.13 EGF83886.1 - 1.2e-54 185.8 60.9 1.8e-51 175.4 16.8 2.2 1 1 1 2 2 2 2 Mitotic checkpoint protein ZapB PF06005.12 EGF83886.1 - 0.0089 16.5 6.8 0.0089 16.5 6.8 6.3 5 2 0 5 5 5 1 Cell division protein ZapB Fmp27_SW PF10305.9 EGF83886.1 - 0.3 11.8 0.1 0.3 11.8 0.1 3.5 3 1 1 4 4 4 0 RNA pol II promoter Fmp27 protein domain E2R135 PF11570.8 EGF83886.1 - 4.8 7.5 8.7 0.7 10.2 1.1 3.2 3 1 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 WD40 PF00400.32 EGF83887.1 - 3.2e-40 135.4 16.8 2.5e-07 31.3 1.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83887.1 - 8.7e-05 22.8 0.7 0.077 13.3 0.1 3.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGF83887.1 - 0.00067 18.5 1.3 0.63 8.7 0.0 3.8 1 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 EGF83887.1 - 0.0016 17.2 2.3 0.23 10.0 0.2 3.7 2 1 2 4 4 4 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGF83887.1 - 0.0049 16.9 0.1 11 6.1 0.0 3.7 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGF83887.1 - 0.041 13.2 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain W_rich_C PF07483.11 EGF83887.1 - 0.31 11.2 1.9 2.5 8.3 0.1 3.2 4 0 0 4 4 4 0 Tryptophan-rich Synechocystis species C-terminal domain GCV_T PF01571.21 EGF83888.1 - 1.4e-08 34.5 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain G-alpha PF00503.20 EGF83889.1 - 2e-89 300.2 5.6 2.3e-89 300.0 5.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF83889.1 - 2e-13 50.2 1.1 6.9e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGF83889.1 - 5.6e-05 23.3 0.1 0.04 14.1 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGF83889.1 - 0.00074 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Ras PF00071.22 EGF83889.1 - 0.00096 18.8 0.9 1.8 8.1 0.0 3.3 2 1 1 3 3 3 2 Ras family SRPRB PF09439.10 EGF83889.1 - 0.027 13.9 0.1 5.1 6.5 0.0 2.7 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGF83889.1 - 0.11 12.6 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 EGF83890.1 - 4.8e-87 292.4 9.3 5.4e-87 292.2 9.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGF83890.1 - 4.9e-15 55.4 1.3 2.4e-11 43.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGF83890.1 - 5.7e-06 26.6 0.2 0.019 15.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGF83890.1 - 0.00014 21.4 0.2 0.26 10.7 0.0 2.6 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 EGF83890.1 - 0.0023 17.6 0.6 0.11 12.1 0.2 2.3 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EGF83890.1 - 0.0071 16.4 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF83890.1 - 0.0097 15.5 1.9 0.73 9.3 1.9 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MFS_1 PF07690.16 EGF83891.1 - 1.6e-26 93.1 45.6 3.5e-23 82.1 10.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF83891.1 - 8.5e-08 31.5 2.4 8.5e-08 31.5 2.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EGF83891.1 - 0.00011 20.8 0.4 0.00011 20.8 0.4 2.2 2 1 0 2 2 2 1 Transmembrane secretion effector Phage_holin_5_1 PF06946.11 EGF83891.1 - 4.7 7.7 6.3 1.7 9.1 2.7 2.1 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 Alginate_lyase PF05426.12 EGF83892.1 - 2.8e-44 151.7 1.4 4.1e-44 151.2 1.4 1.3 1 0 0 1 1 1 1 Alginate lyase NMD3 PF04981.13 EGF83894.1 - 1.2e-80 270.5 3.3 1.6e-80 270.1 3.3 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EGF83894.1 - 0.1 12.6 5.7 0.88 9.6 4.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 EGF83894.1 - 0.59 10.1 8.6 2.1 8.3 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) GNAT_acetyltr_2 PF13718.6 EGF83895.1 - 2.1e-96 321.7 0.0 3.5e-96 321.0 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EGF83895.1 - 1.3e-62 210.8 0.0 5.8e-62 208.7 0.0 2.1 3 0 0 3 3 3 1 Helicase tRNA_bind_2 PF13725.6 EGF83895.1 - 1.7e-58 198.1 2.2 8.2e-58 195.9 2.2 2.0 1 1 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 EGF83895.1 - 2.3e-33 114.0 0.1 6.2e-33 112.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 EGF83895.1 - 0.025 14.8 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGF83895.1 - 0.045 14.2 0.0 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_22 PF13401.6 EGF83895.1 - 0.055 13.7 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Tmemb_cc2 PF10267.9 EGF83897.1 - 0.039 13.1 0.1 0.049 12.8 0.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CEP44 PF15007.6 EGF83898.1 - 5.1e-44 149.5 0.1 8.8e-44 148.7 0.1 1.4 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Taxilin PF09728.9 EGF83898.1 - 0.013 14.8 1.4 0.019 14.2 1.4 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein SHE3 PF17078.5 EGF83898.1 - 0.018 14.8 0.7 0.05 13.3 0.7 1.7 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 MIP-T3_C PF17749.1 EGF83898.1 - 0.024 14.6 0.8 0.36 10.8 0.1 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region H-kinase_dim PF02895.14 EGF83898.1 - 0.056 13.8 0.6 0.13 12.6 0.6 1.6 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Tup_N PF08581.10 EGF83898.1 - 0.15 12.4 2.4 0.32 11.3 2.4 1.5 1 0 0 1 1 1 0 Tup N-terminal Ribosomal_L31e PF01198.19 EGF83900.1 - 7.8e-40 135.0 0.9 1.2e-39 134.5 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EGF83900.1 - 0.0034 17.4 0.1 0.0041 17.2 0.1 1.2 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Pam16 PF03656.13 EGF83901.1 - 9.4e-06 25.7 0.0 1.1e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EGF83901.1 - 4.6e-05 23.5 0.1 6.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.31 EGF83902.1 - 3.4e-09 36.4 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 UBA/TS-N domain CUE PF02845.16 EGF83902.1 - 0.0077 15.9 0.1 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 EGF83902.1 - 0.0089 15.8 0.1 0.096 12.5 0.1 2.2 2 0 0 2 2 2 1 UBA-like domain HTH_8 PF02954.19 EGF83902.1 - 0.15 11.9 0.3 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family PPR PF01535.20 EGF83903.1 - 2.5e-10 39.9 0.7 0.082 13.2 0.0 6.1 6 0 0 6 6 6 3 PPR repeat PPR_2 PF13041.6 EGF83903.1 - 2.4e-07 30.8 0.1 0.017 15.3 0.0 4.0 1 1 2 3 3 3 2 PPR repeat family PPR_1 PF12854.7 EGF83903.1 - 0.00028 20.5 0.2 0.018 14.7 0.1 2.9 2 0 0 2 2 2 1 PPR repeat PPR_long PF17177.4 EGF83903.1 - 0.0024 17.3 0.0 0.62 9.4 0.0 3.1 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP Peptidase_M36 PF02128.15 EGF83904.1 - 1.1e-133 446.0 4.6 1.4e-133 445.6 4.6 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF83904.1 - 4.8e-08 32.7 0.1 1.1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EGF83904.1 - 4.7e-06 27.1 0.3 8.7e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DEAD PF00270.29 EGF83906.1 - 1.9e-45 154.8 0.0 3.8e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGF83906.1 - 1.1e-24 86.9 0.0 6.3e-24 84.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGF83906.1 - 7.6e-17 61.3 0.1 1.5e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGF83906.1 - 1.8e-06 28.1 0.0 3.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CD34_antigen PF06365.12 EGF83907.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM154 PF15102.6 EGF83907.1 - 0.26 11.2 4.0 0.1 12.5 0.5 2.1 2 0 0 2 2 2 0 TMEM154 protein family MMR_HSR1_Xtn PF16897.5 EGF83908.1 - 1e-41 141.3 1.7 1.8e-41 140.4 1.7 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGF83908.1 - 1.8e-21 76.3 0.0 3.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EGF83908.1 - 6.7e-21 74.1 0.0 1.3e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGF83908.1 - 3e-12 46.3 0.0 4.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGF83908.1 - 0.016 15.3 0.3 0.43 10.6 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Rhodanese PF00581.20 EGF83909.1 - 4.5e-14 52.9 0.0 6.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain tRNA-synt_2b PF00587.25 EGF83910.1 - 3.5e-37 128.1 0.0 6.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGF83910.1 - 1.5e-16 60.3 0.1 3.1e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGF83910.1 - 1.6e-10 40.9 0.0 3.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGF83910.1 - 2.9e-09 36.8 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain Nop10p PF04135.12 EGF83910.1 - 0.1 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family GATA PF00320.27 EGF83911.1 - 2.6e-14 52.5 3.5 5.4e-14 51.5 3.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 EGF83911.1 - 0.013 15.6 0.7 0.032 14.3 0.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Det1 PF09737.9 EGF83915.1 - 9.7e-94 314.7 1.4 3.5e-36 125.1 0.3 3.1 3 0 0 3 3 3 3 De-etiolated protein 1 Det1 Glyco_hydro_47 PF01532.20 EGF83916.1 - 1.2e-113 380.4 1.2 2.4e-113 379.5 1.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 T3SchapCesA PF11439.8 EGF83916.1 - 0.0047 17.0 0.3 0.12 12.5 0.1 2.6 2 0 0 2 2 2 1 Type III secretion system filament chaperone CesA RNase_T PF00929.24 EGF83917.1 - 1.2e-15 58.4 0.0 3.5e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Exonuclease HTH_AraC PF00165.23 EGF83917.1 - 0.11 12.6 0.0 4.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF5304 PF17230.2 EGF83918.1 - 0.042 14.1 0.2 0.068 13.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5304) HTH_9 PF08221.11 EGF83918.1 - 0.1 12.7 0.5 0.43 10.7 0.2 2.1 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain KAR PF15222.6 EGF83918.1 - 3 8.2 14.0 3.5 8.0 2.1 2.7 1 1 1 2 2 2 0 Kidney androgen-regulated DUF760 PF05542.11 EGF83918.1 - 9.5 6.7 6.9 1.9e+02 2.5 6.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF760) dCMP_cyt_deam_1 PF00383.23 EGF83919.1 - 9.3e-24 83.2 0.4 3.1e-11 43.1 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGF83919.1 - 4.5e-10 39.4 0.0 4e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 MafB19-like deaminase RsfS PF02410.15 EGF83920.1 - 6.5e-25 87.4 0.6 2.9e-24 85.4 0.0 2.2 2 1 0 2 2 2 1 Ribosomal silencing factor during starvation Peptidase_M36 PF02128.15 EGF83921.1 - 2e-137 458.3 6.3 2.7e-137 457.9 6.3 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGF83921.1 - 1e-15 57.2 0.5 2.4e-15 56.1 0.5 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EGF83921.1 - 0.0068 16.9 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain F-box PF00646.33 EGF83922.1 - 0.0031 17.3 0.1 0.0031 17.3 0.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGF83922.1 - 0.024 14.5 2.3 0.064 13.1 0.1 2.8 3 0 0 3 3 3 0 F-box-like E1_DerP2_DerF2 PF02221.15 EGF83923.1 - 1.4e-20 74.1 0.0 1.5e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 ML domain zf-MIZ PF02891.20 EGF83923.1 - 0.044 13.5 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger CRC_subunit PF08624.10 EGF83924.1 - 1.7e-40 138.6 0.0 4e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 EGF83924.1 - 6.5e-20 70.8 47.9 5e-12 45.5 8.5 4.8 3 1 1 4 4 4 3 PHD-finger DUF1293 PF06950.11 EGF83924.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) FA_desaturase PF00487.24 EGF83925.1 - 1.8e-27 96.8 26.6 1.8e-27 96.8 26.6 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 EGF83925.1 - 2.8e-13 49.8 0.0 5.5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMGL-like PF00682.19 EGF83926.1 - 3.4e-79 266.1 0.1 4.6e-79 265.7 0.1 1.2 1 0 0 1 1 1 1 HMGL-like Pro_isomerase PF00160.21 EGF83928.1 - 6.6e-46 156.5 0.0 1.5e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGF83928.1 - 2.2e-12 46.6 0.1 2.4e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4675 PF15720.5 EGF83928.1 - 0.1 12.4 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Aft1_HRR PF11787.8 EGF83928.1 - 0.2 12.9 1.1 0.47 11.7 1.1 1.6 1 0 0 1 1 1 0 Aft1 HRR domain Iso_dh PF00180.20 EGF83929.1 - 6.4e-88 295.2 0.0 1.7e-86 290.6 0.0 2.0 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COX6A PF02046.15 EGF83931.1 - 3.3e-09 37.2 0.1 3.9e-09 37.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa NdhL PF10716.9 EGF83931.1 - 0.031 14.2 0.5 0.043 13.8 0.5 1.2 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Pkinase PF00069.25 EGF83932.1 - 1.1e-62 211.8 0.0 1.8e-62 211.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF83932.1 - 6.2e-34 117.5 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EGF83932.1 - 9.7e-18 63.8 22.9 4.4e-10 39.3 10.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EGF83932.1 - 6.6e-17 61.4 12.2 7.5e-09 35.6 2.9 2.7 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 EGF83932.1 - 1.3e-06 29.0 1.1 1.3e-06 29.0 1.1 2.3 2 1 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGF83932.1 - 0.00011 21.3 0.0 0.00022 20.3 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 EGF83932.1 - 0.0069 16.7 14.1 0.06 13.7 4.9 2.6 2 0 0 2 2 2 2 C1 domain Uds1 PF15456.6 EGF83932.1 - 0.33 11.1 10.2 10 6.3 0.2 3.4 2 1 0 2 2 2 0 Up-regulated During Septation PHD PF00628.29 EGF83932.1 - 1.2 9.1 18.5 1.4 8.8 7.4 2.5 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 EGF83932.1 - 2.8 8.1 11.4 0.27 11.4 2.6 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Cytochrom_B561 PF03188.16 EGF83933.1 - 0.0019 18.3 2.1 0.0019 18.3 2.1 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 EGF83933.1 - 0.032 14.3 6.7 1.2 9.2 0.5 2.5 1 1 1 2 2 2 0 Ferric reductase like transmembrane component NRIP1_repr_3 PF15689.5 EGF83934.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.4 3 1 1 4 4 4 0 Nuclear receptor-interacting protein 1 repression 3 RNase_P_Rpp14 PF01900.19 EGF83935.1 - 2.2e-30 105.0 0.4 2.6e-30 104.7 0.4 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Myc-LZ PF02344.15 EGF83936.1 - 0.33 11.1 26.8 13 6.0 0.2 10.1 9 0 0 9 9 9 0 Myc leucine zipper domain EF-hand_13 PF17958.1 EGF83937.1 - 3.6e-24 84.4 0.1 9.7e-23 79.8 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EGF83937.1 - 5.1e-14 52.5 2.4 2.2e-13 50.4 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 EGF83937.1 - 0.0034 17.2 0.1 0.026 14.4 0.1 2.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGF83937.1 - 0.0073 15.8 1.1 0.04 13.5 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EGF83937.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 EGF83937.1 - 0.2 11.5 2.9 0.39 10.6 0.1 3.0 4 0 0 4 4 4 0 EF-hand domain pair DmsC PF04976.12 EGF83937.1 - 0.25 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) TBCC PF07986.12 EGF83938.1 - 5.1e-35 119.8 4.3 7.8e-35 119.2 4.3 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TraA PF05513.11 EGF83938.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 TraA CAP_C PF08603.11 EGF83938.1 - 0.5 10.0 4.8 7.9 6.1 0.4 2.1 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal DUF4407 PF14362.6 EGF83940.1 - 1.8 7.9 5.5 2.3 7.5 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mcl1_mid PF12341.8 EGF83942.1 - 4.8e-90 301.9 0.1 2.9e-89 299.4 0.0 2.1 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EGF83942.1 - 3e-20 72.1 5.2 1.8e-05 25.4 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83942.1 - 3.9e-07 30.3 0.1 0.002 18.4 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGF83942.1 - 4.3e-05 22.6 0.2 0.62 9.0 0.0 3.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGF83942.1 - 0.0045 16.4 0.0 0.036 13.4 0.0 2.3 2 1 1 3 3 3 1 WD40-like domain PD40 PF07676.12 EGF83942.1 - 0.086 12.8 0.3 33 4.6 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.8 EGF83942.1 - 0.14 12.2 8.7 0.36 10.9 8.0 2.1 1 1 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal F-box PF00646.33 EGF83943.1 - 0.0028 17.5 1.8 0.16 11.9 0.7 2.9 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 EGF83943.1 - 0.021 14.7 0.8 0.054 13.4 0.4 1.9 2 0 0 2 2 2 0 F-box-like RGS PF00615.19 EGF83944.1 - 1.5e-14 54.3 0.7 2.5e-14 53.5 0.7 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1516 PF07457.11 EGF83944.1 - 1.5 9.1 10.1 0.13 12.4 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1516) Peptidase_U4 PF03419.13 EGF83944.1 - 2.8 7.2 14.2 0.11 11.7 7.9 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF2157 PF09925.9 EGF83944.1 - 8.1 6.2 6.7 4.3 7.1 1.9 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) RGS PF00615.19 EGF83945.1 - 1.9e-18 66.8 0.1 3.8e-18 65.9 0.0 1.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS PF00615.19 EGF83947.1 - 1.3e-13 51.3 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_U4 PF03419.13 EGF83947.1 - 0.73 9.1 8.9 0.29 10.4 6.2 1.7 1 1 1 2 2 2 0 Sporulation factor SpoIIGA RGS PF00615.19 EGF83948.1 - 8.2e-14 51.9 0.4 1.4e-13 51.2 0.4 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain RNA_pol_Rpb1_3 PF04983.18 EGF83948.1 - 0.017 15.0 0.2 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 RGS PF00615.19 EGF83949.1 - 7e-13 48.9 1.6 9.5e-13 48.5 0.3 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF2157 PF09925.9 EGF83949.1 - 0.0026 17.6 0.7 0.0041 16.9 0.7 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) RGS-like PF09128.11 EGF83949.1 - 0.047 13.4 0.4 0.083 12.6 0.4 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Sigma_reg_N PF13800.6 EGF83949.1 - 1.2 9.4 4.2 24 5.3 0.6 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Rit1_C PF17184.4 EGF83950.1 - 6.7e-91 304.5 0.1 9e-91 304.1 0.1 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGF83950.1 - 2.2e-24 85.9 0.0 5e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain DSPc PF00782.20 EGF83950.1 - 6.2e-10 39.0 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGF83950.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family ABC_tran PF00005.27 EGF83951.1 - 1.6e-31 109.6 0.0 3.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGF83951.1 - 1.4e-16 60.6 29.1 2.1e-16 60.0 29.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGF83951.1 - 7e-16 58.9 0.6 1.5e-09 38.1 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGF83951.1 - 0.0027 17.2 0.1 0.029 13.8 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGF83951.1 - 0.0054 17.3 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EGF83951.1 - 0.024 14.9 0.0 0.24 11.7 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EGF83951.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGF83951.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 EGF83951.1 - 0.17 10.5 0.0 2.3 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4498 PF14926.6 EGF83953.1 - 1.4e-88 296.4 1.4 1.7e-88 296.1 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Fra10Ac1 PF09725.9 EGF83954.1 - 2.1e-47 160.3 9.2 2.1e-47 160.3 9.2 2.1 3 0 0 3 3 3 1 Folate-sensitive fragile site protein Fra10Ac1 TILa PF12714.7 EGF83954.1 - 0.093 12.7 0.5 0.093 12.7 0.5 2.4 2 0 0 2 2 2 0 TILa domain Lar_restr_allev PF14354.6 EGF83954.1 - 2.9 8.3 6.1 44 4.6 6.1 2.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar Yippee-Mis18 PF03226.14 EGF83955.1 - 0.18 12.1 2.7 2.3 8.5 2.8 2.6 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4940 PF16298.5 EGF83956.1 - 0.089 12.4 0.2 6.1 6.5 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4940) WD40 PF00400.32 EGF83957.1 - 2.8e-10 40.6 11.3 0.018 15.9 0.5 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83957.1 - 7.7e-06 26.1 1.8 1.4 9.2 0.1 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Pyr_redox_2 PF07992.14 EGF83958.1 - 7.1e-49 166.6 0.1 8.3e-49 166.4 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF83958.1 - 2.6e-16 60.0 0.5 1.6e-14 54.2 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGF83958.1 - 3.6e-16 59.3 0.0 5.1e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGF83958.1 - 0.0005 19.5 0.5 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGF83958.1 - 0.00085 18.6 0.0 0.0032 16.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EGF83958.1 - 0.0033 16.6 1.0 0.018 14.2 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 EGF83958.1 - 0.0038 16.4 0.0 0.048 12.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGF83958.1 - 0.0069 16.6 0.4 0.068 13.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGF83958.1 - 0.018 14.2 5.6 0.039 13.0 0.3 3.4 4 1 1 5 5 5 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EGF83958.1 - 0.04 14.3 0.2 0.33 11.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Attacin_N PF03768.15 EGF83958.1 - 0.065 13.4 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 Attacin, N-terminal region HI0933_like PF03486.14 EGF83958.1 - 0.073 11.8 1.9 0.11 11.2 0.4 2.1 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 EGF83958.1 - 0.16 10.8 0.2 0.35 9.7 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase ketoacyl-synt PF00109.26 EGF83959.1 - 1.5e-54 185.3 0.1 2.3e-54 184.6 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGF83959.1 - 3.8e-36 123.7 0.9 6.5e-36 122.9 0.9 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGF83959.1 - 2.7e-06 27.0 0.2 5.6e-06 25.9 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGF83959.1 - 0.019 14.6 1.1 0.088 12.5 0.2 2.4 2 0 0 2 2 2 0 Thiolase, C-terminal domain Lipase_3 PF01764.25 EGF83960.1 - 3.5e-12 46.4 0.0 7.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PHD PF00628.29 EGF83961.1 - 3.3e-09 36.5 6.5 6.5e-09 35.6 6.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGF83961.1 - 0.0081 15.7 2.4 0.016 14.7 2.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EGF83961.1 - 1.3 9.1 3.4 3 8.0 3.4 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Lactamase_B_4 PF13691.6 EGF83962.1 - 6.2e-20 70.6 0.4 5.3e-18 64.5 0.0 3.4 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EGF83962.1 - 1.4e-15 57.4 0.0 9.3e-12 44.9 0.1 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGF83962.1 - 0.0033 17.4 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2415 PF10313.9 EGF83964.1 - 2.1e-12 46.8 0.1 8.3e-12 44.8 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EGF83964.1 - 4.3e-05 23.7 0.1 0.35 11.2 0.1 4.3 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 EGF83964.1 - 0.0016 17.3 0.1 0.0044 15.8 0.0 1.7 1 1 1 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 EGF83964.1 - 0.014 16.3 12.5 5.4 8.1 0.4 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat BBS2_N PF14781.6 EGF83964.1 - 0.023 14.6 0.3 3.6 7.5 0.0 3.6 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal PD40 PF07676.12 EGF83964.1 - 0.035 14.1 0.4 15 5.7 0.3 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 EGF83964.1 - 0.081 11.2 0.0 0.25 9.6 0.0 1.7 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1604 PF07713.13 EGF83965.1 - 0.037 13.9 0.1 0.077 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) PAP1 PF08601.10 EGF83965.1 - 1.7 8.3 9.9 2.7 7.6 9.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF1712 PF08217.11 EGF83966.1 - 3.2e-29 101.9 5.5 1.1e-26 93.5 3.2 3.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) AMP-binding PF00501.28 EGF83967.1 - 2.3e-100 336.2 0.0 3e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Erv26 PF04148.13 EGF83968.1 - 9.4e-39 133.4 15.0 2.7e-35 122.1 15.0 2.7 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 F-box_5 PF18511.1 EGF83968.1 - 0.19 11.4 0.6 0.46 10.1 0.6 1.6 1 0 0 1 1 1 0 F-box RRM_1 PF00076.22 EGF83970.1 - 8e-18 64.0 0.0 1.2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGF83970.1 - 7.6e-08 32.2 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGF83970.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 EGF83970.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif PHM7_cyt PF14703.6 EGF83970.1 - 0.028 14.6 0.0 2.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 EGF83970.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RL domain Not3 PF04065.15 EGF83971.1 - 0.00028 20.4 4.2 0.00028 20.4 4.2 2.2 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component ATG16 PF08614.11 EGF83971.1 - 0.0025 18.1 10.5 0.1 12.8 9.2 2.8 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DivIC PF04977.15 EGF83971.1 - 0.01 15.6 6.7 0.18 11.6 1.1 3.6 3 1 0 3 3 3 0 Septum formation initiator Fzo_mitofusin PF04799.13 EGF83971.1 - 0.42 10.1 7.6 5.5 6.5 2.9 2.8 2 0 0 2 2 2 0 fzo-like conserved region NPV_P10 PF05531.12 EGF83971.1 - 0.64 10.5 9.5 0.13 12.7 1.5 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EGF83971.1 - 1 9.7 4.4 3.5 7.9 0.5 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_B PF05405.14 EGF83971.1 - 1.1 8.8 10.5 0.61 9.7 4.6 3.0 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) HIP1_clath_bdg PF16515.5 EGF83971.1 - 1.2 9.8 12.7 0.19 12.4 2.8 3.4 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 EGF83971.1 - 1.3 8.3 8.8 0.31 10.4 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 EGF83971.1 - 2 9.1 7.7 5.7 7.6 0.0 3.8 3 1 1 4 4 4 0 SlyX DUF16 PF01519.16 EGF83971.1 - 4.3 7.9 12.4 6.6 7.3 2.7 3.9 4 1 1 5 5 5 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EGF83971.1 - 4.6 7.3 12.2 5.5 7.0 2.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 EGF83971.1 - 7.4 6.6 14.9 0.15 12.2 4.3 2.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ras PF00071.22 EGF83972.1 - 3.8e-54 182.7 0.1 4.2e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF83972.1 - 4.6e-20 72.0 0.0 8.4e-20 71.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF83972.1 - 8.3e-09 35.1 0.0 9e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF83972.1 - 4.1e-07 29.7 0.0 8.1e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGF83972.1 - 0.0024 17.9 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF83972.1 - 0.0044 16.9 1.7 1.7 8.5 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 EGF83972.1 - 0.029 14.1 0.8 0.76 9.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGF83972.1 - 0.054 13.0 0.3 0.13 11.8 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EGF83972.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Xpo1 PF08389.12 EGF83973.1 - 9.8e-20 71.1 7.7 2.3e-19 70.0 4.2 3.2 2 1 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EGF83973.1 - 7e-09 35.5 0.5 1.7e-07 31.1 0.1 3.3 3 2 0 3 3 3 1 Importin-beta N-terminal domain Importin_rep PF18773.1 EGF83973.1 - 0.036 13.8 1.5 0.077 12.7 0.2 2.2 2 0 0 2 2 2 0 Importin 13 repeat TAF6_C PF07571.13 EGF83973.1 - 0.084 13.2 0.2 3.1 8.2 0.0 3.4 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain SCAI PF12070.8 EGF83974.1 - 8.6e-192 638.7 2.3 1.2e-191 638.3 2.3 1.1 1 0 0 1 1 1 1 Protein SCAI PseudoU_synth_2 PF00849.22 EGF83976.1 - 1.5e-25 90.1 0.0 1.9e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Velvet PF11754.8 EGF83977.1 - 6.1e-54 183.6 0.3 4.8e-51 174.1 0.3 2.0 1 1 0 1 1 1 1 Velvet factor PPP4R2 PF09184.11 EGF83978.1 - 2.8e-20 73.1 0.4 4.1e-20 72.6 0.4 1.5 1 1 0 1 1 1 1 PPP4R2 Pyridoxal_deC PF00282.19 EGF83978.1 - 0.016 14.0 0.1 0.02 13.6 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Rap_GAP PF02145.15 EGF83979.1 - 4.7e-32 111.0 0.0 8.6e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EGF83979.1 - 3.2e-28 98.9 2.6 5e-28 98.2 2.6 1.3 1 0 0 1 1 1 1 Tuberin DUF1751 PF08551.10 EGF83980.1 - 3.2e-09 37.2 11.5 8.9e-09 35.8 5.0 2.9 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) V-ATPase_G PF03179.15 EGF83982.1 - 2.7e-29 101.8 9.8 3.1e-29 101.6 9.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HemN_C PF06969.16 EGF83982.1 - 0.029 14.4 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 HemN C-terminal domain DUF2815 PF10991.8 EGF83982.1 - 0.1 12.6 1.5 0.12 12.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) PSP1 PF04468.12 EGF83983.1 - 9.3e-34 115.6 2.6 1.4e-33 115.1 2.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region MRP-S33 PF08293.11 EGF83984.1 - 0.00093 19.4 0.2 0.0014 18.9 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DHHC PF01529.20 EGF83985.1 - 3.6e-34 117.7 7.9 3.6e-34 117.7 7.9 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase Reo_sigmaC PF04582.12 EGF83986.1 - 0.048 13.9 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein C-terminal domain UPF0449 PF15136.6 EGF83986.1 - 0.36 11.3 5.3 1.9 9.0 0.1 2.8 1 1 1 3 3 3 0 Uncharacterised protein family UPF0449 CENP-F_leu_zip PF10473.9 EGF83986.1 - 0.6 10.1 8.2 0.58 10.2 2.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Stathmin PF00836.19 EGF83986.1 - 0.83 9.6 4.2 0.85 9.6 0.5 2.5 2 1 1 3 3 3 0 Stathmin family Fib_alpha PF08702.10 EGF83986.1 - 1.6 8.9 7.8 1.4 9.1 0.2 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SKA2 PF16740.5 EGF83986.1 - 2.1 8.2 6.0 1.2 9.0 2.3 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Nsp1_C PF05064.13 EGF83986.1 - 3.4 7.5 6.3 0.78 9.6 0.9 2.4 2 1 1 3 3 3 0 Nsp1-like C-terminal region Peptidase_C13 PF01650.18 EGF83987.1 - 1.2e-43 149.5 0.1 1.3e-43 149.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 EGF83987.1 - 0.043 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute SURF6 PF04935.12 EGF83988.1 - 5.7e-35 120.9 45.6 5.7e-35 120.9 45.6 2.7 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EGF83988.1 - 1.2e-17 64.2 0.3 1.2e-17 64.2 0.3 5.1 4 2 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 Herpes_UL3 PF03369.13 EGF83988.1 - 2 8.9 9.1 7.8 7.0 0.3 2.8 2 1 0 2 2 2 0 Herpesvirus UL3 protein Yip1 PF04893.17 EGF83989.1 - 3.2e-15 56.3 15.8 5.1e-15 55.6 15.8 1.4 1 0 0 1 1 1 1 Yip1 domain WD40 PF00400.32 EGF83990.1 - 6.5e-30 102.7 1.0 1.4e-07 32.1 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF83990.1 - 1.6e-16 60.3 0.1 5.8e-06 26.5 0.0 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 EGF83990.1 - 7.4e-10 38.3 1.2 1.4e-09 37.4 1.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 EGF83990.1 - 8.9e-08 31.5 2.0 0.13 11.2 0.0 4.9 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGF83990.1 - 0.00024 19.9 0.1 0.12 11.0 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGF83990.1 - 0.011 14.5 0.7 0.38 9.4 0.0 2.8 1 1 1 3 3 3 0 Nup133 N terminal like PQQ_3 PF13570.6 EGF83990.1 - 0.012 16.1 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 EGF83990.1 - 0.014 14.7 0.2 0.3 10.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 EGF83990.1 - 0.016 15.1 0.2 11 5.8 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A tRNA-synt_1c PF00749.21 EGF83991.1 - 1.5e-101 339.4 0.1 2e-101 339.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGF83991.1 - 3e-32 111.9 3.6 4.2e-32 111.4 0.4 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 EGF83991.1 - 4.6e-28 97.2 0.1 9.3e-28 96.2 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EGF83991.1 - 0.0095 16.1 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGF83991.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_transp_aux PF09822.9 EGF83992.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 EGF83992.1 - 0.00011 21.2 0.0 0.0016 17.3 0.0 2.0 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2977 PF11192.8 EGF83992.1 - 0.034 14.3 0.3 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) DUF4709 PF15821.5 EGF83992.1 - 0.14 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) PITH PF06201.13 EGF83993.1 - 1.7e-44 151.7 0.0 2e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Phytochelatin PF05023.14 EGF83994.1 - 7.6e-62 208.3 0.0 2.4e-59 200.1 0.0 2.4 1 1 1 2 2 2 2 Phytochelatin synthase CDC14 PF08045.11 EGF83994.1 - 0.048 12.8 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component Cytochrom_B562 PF07361.11 EGF83994.1 - 0.058 14.1 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b562 Sel1 PF08238.12 EGF83995.1 - 1.1e-41 140.4 18.9 2.3e-09 37.6 0.6 6.3 6 1 0 6 6 6 5 Sel1 repeat TPR_16 PF13432.6 EGF83995.1 - 3.1e-06 27.7 11.4 0.00013 22.5 1.4 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGF83995.1 - 0.0022 17.7 19.9 0.63 10.0 0.1 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF83995.1 - 0.0045 17.0 17.5 0.31 11.3 0.0 7.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGF83995.1 - 0.0073 16.1 18.4 0.1 12.5 0.1 6.6 6 3 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGF83995.1 - 0.0074 16.4 17.5 1.2 9.5 0.1 7.2 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGF83995.1 - 0.037 14.4 8.3 2.5 8.7 0.2 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGF83995.1 - 0.15 12.4 18.1 9 6.7 1.2 5.8 4 3 0 4 4 4 0 Tetratricopeptide repeat BRO1 PF03097.18 EGF83996.1 - 7e-127 423.4 0.9 1.2e-126 422.6 0.9 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGF83996.1 - 2e-57 194.7 6.8 2e-57 194.7 6.8 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV WGG PF10273.9 EGF83997.1 - 3.3e-14 53.3 0.0 1e-13 51.7 0.0 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 ABC1 PF03109.16 EGF83998.1 - 2e-21 76.4 0.0 6.1e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 ABC1 family DUF4327 PF14217.6 EGF83998.1 - 0.16 12.1 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) Pepdidase_M14_N PF18027.1 EGF84000.1 - 3.6e-13 49.8 0.1 9.2e-13 48.5 0.1 1.8 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EGF84000.1 - 1e-11 45.2 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGF84000.1 - 0.027 13.5 0.1 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF826 PF05696.11 EGF84000.1 - 0.09 12.9 0.4 0.72 10.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF826) RIC1 PF07064.13 EGF84001.1 - 4.5e-57 193.4 0.4 1.1e-46 159.3 0.2 2.6 1 1 1 2 2 2 2 RIC1 ANAPC4_WD40 PF12894.7 EGF84001.1 - 1.1e-05 25.6 0.0 0.062 13.6 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CHCH PF06747.13 EGF84002.1 - 3.4e-06 27.0 0.1 5.3e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 EGF84002.1 - 0.064 13.0 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) IBR PF01485.21 EGF84003.1 - 9.6e-21 73.8 53.5 2.3e-12 46.9 9.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGF84003.1 - 0.00012 21.8 41.2 0.0011 18.8 7.1 4.4 3 2 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 EGF84003.1 - 0.027 14.3 4.5 0.31 10.9 0.0 2.8 3 0 0 3 3 3 0 UBA-like domain zf-C3HC4_2 PF13923.6 EGF84003.1 - 0.045 13.6 45.4 0.11 12.4 7.0 4.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF84003.1 - 0.092 13.1 48.9 0.078 13.3 11.4 3.9 3 0 0 3 3 3 0 Ring finger domain Tk-SP_N-pro PF18237.1 EGF84003.1 - 0.12 12.4 0.2 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Tk-SP N-propeptide domain zf-RING_UBOX PF13445.6 EGF84003.1 - 3.3 7.8 40.5 0.19 11.8 6.2 4.1 2 1 1 3 3 3 0 RING-type zinc-finger Pro_isomerase PF00160.21 EGF84004.1 - 7.7e-45 153.0 0.0 8.6e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 EGF84005.1 - 1.4e-78 263.9 0.0 1.6e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84005.1 - 5.4e-34 117.7 0.0 7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF84005.1 - 4.8e-06 25.8 0.1 0.00011 21.3 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF84005.1 - 0.00064 19.1 0.2 0.076 12.3 0.0 2.3 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGF84005.1 - 0.0014 18.6 0.0 0.013 15.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGF84005.1 - 0.0068 15.5 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 HbrB PF08539.11 EGF84006.1 - 8.8e-27 94.1 3.0 2.2e-26 92.9 0.4 2.4 2 1 0 2 2 2 1 HbrB-like HLH PF00010.26 EGF84007.1 - 1.2e-08 34.7 0.1 2.9e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomyosin_1 PF12718.7 EGF84007.1 - 0.023 14.8 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Tropomyosin like FANCI_S2 PF14676.6 EGF84007.1 - 0.18 12.1 1.4 0.21 11.9 0.2 1.7 2 0 0 2 2 2 0 FANCI solenoid 2 Cnd1 PF12717.7 EGF84008.1 - 9.8e-52 175.3 14.6 6.5e-49 166.1 3.0 5.0 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EGF84008.1 - 9.8e-28 97.1 1.8 3.8e-27 95.2 1.8 2.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 EGF84008.1 - 6.5e-08 32.9 0.0 0.004 17.5 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGF84008.1 - 1.2e-07 31.4 0.2 1.8 9.0 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Amino_oxidase PF01593.24 EGF84008.1 - 9.8e-07 28.4 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF4506 PF14958.6 EGF84008.1 - 1.9e-06 27.4 0.1 4.5e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) RTP1_C1 PF10363.9 EGF84008.1 - 0.00012 22.2 3.4 0.11 12.7 0.2 4.0 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 NAD_binding_9 PF13454.6 EGF84008.1 - 0.017 15.2 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding HEAT_EZ PF13513.6 EGF84008.1 - 0.032 14.8 3.4 47 4.6 0.0 5.6 6 0 0 6 6 6 0 HEAT-like repeat NAD_binding_8 PF13450.6 EGF84009.1 - 5.1e-12 45.8 0.1 1.3e-11 44.6 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGF84009.1 - 2.1e-07 30.9 0.6 3.2e-07 30.3 0.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGF84009.1 - 1.7e-06 27.6 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EGF84009.1 - 2.9e-05 23.4 0.0 4.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGF84009.1 - 7.7e-05 22.1 0.0 8.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGF84009.1 - 0.00092 18.4 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 EGF84009.1 - 0.0017 17.3 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 MCRA family Trp_halogenase PF04820.14 EGF84009.1 - 0.0052 15.7 0.1 0.007 15.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.19 EGF84009.1 - 0.0075 15.6 0.0 0.077 12.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EGF84009.1 - 0.0086 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EGF84009.1 - 0.016 14.5 0.0 0.034 13.4 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGF84009.1 - 0.025 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGF84009.1 - 0.03 14.9 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGF84009.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Mqo PF06039.15 EGF84009.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 EGF84009.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EGF84009.1 - 0.21 10.2 0.0 0.38 9.4 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein DUF1640 PF07798.11 EGF84010.1 - 6.1e-27 94.8 5.3 6.6e-27 94.7 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3450 PF11932.8 EGF84010.1 - 0.095 12.0 4.2 0.19 11.0 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 EGF84010.1 - 0.22 11.0 3.2 0.76 9.3 0.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 EGF84010.1 - 0.32 11.0 3.4 0.74 9.9 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Pet127 PF08634.10 EGF84011.1 - 6.5e-96 321.0 3.8 1.1e-95 320.3 3.8 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Mito_carr PF00153.27 EGF84012.1 - 6.3e-52 173.5 10.0 6.5e-20 70.9 0.4 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF84012.1 - 0.0008 18.6 5.1 0.016 14.4 5.1 2.6 1 1 0 1 1 1 1 Gammaproteobacterial serine protease LRR_8 PF13855.6 EGF84013.1 - 6e-38 128.4 58.3 6.8e-09 35.4 8.9 9.0 3 3 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EGF84013.1 - 5.7e-35 118.8 68.7 1.3e-06 28.6 0.9 11.2 7 3 3 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF84013.1 - 5e-07 29.4 52.3 1.3 9.9 0.0 14.8 16 2 0 16 16 16 4 Leucine Rich Repeat LRR_6 PF13516.6 EGF84013.1 - 0.0098 15.9 56.7 1.5 9.1 0.8 12.1 14 0 0 14 14 14 6 Leucine Rich repeat Mannosyl_trans3 PF11051.8 EGF84014.1 - 5.9e-45 153.8 0.0 9.2e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Gpi1 PF05024.15 EGF84015.1 - 9.6e-67 224.7 11.9 2.5e-66 223.4 11.9 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) RabGAP-TBC PF00566.18 EGF84017.1 - 7e-39 133.7 0.6 1.3e-38 132.9 0.2 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EGF84017.1 - 2.3e-26 92.7 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84017.1 - 1.2e-14 54.2 0.0 2.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF84017.1 - 0.0036 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Rhodanese PF00581.20 EGF84017.1 - 0.0044 17.5 0.0 0.009 16.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain SepA PF17080.5 EGF84017.1 - 0.16 12.3 6.4 0.35 11.2 6.4 1.5 1 0 0 1 1 1 0 Multidrug Resistance efflux pump Ribosomal_L1 PF00687.21 EGF84018.1 - 3.5e-59 200.0 7.5 3.5e-59 200.0 7.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family UBA PF00627.31 EGF84019.1 - 0.0024 17.8 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Methyltransf_PK PF05891.12 EGF84020.1 - 1.3e-79 266.8 0.0 1.5e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGF84020.1 - 7.2e-12 45.9 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF84020.1 - 7.3e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF84020.1 - 9.9e-10 39.1 0.0 1.5e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF84020.1 - 3.5e-06 27.0 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF84020.1 - 9.5e-06 25.3 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGF84020.1 - 0.00021 21.1 0.1 0.00032 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGF84020.1 - 0.0024 17.2 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 EGF84020.1 - 0.0035 17.3 0.0 0.0093 15.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGF84020.1 - 0.077 12.3 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 EGF84020.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB CoA_transf_3 PF02515.17 EGF84024.1 - 2.6e-133 444.7 0.0 3.1e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Ribonuc_P_40 PF08584.11 EGF84025.1 - 1.4e-43 149.2 0.0 9.4e-22 77.6 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit TAFII55_N PF04658.13 EGF84026.1 - 8.1e-46 155.7 0.0 2e-45 154.4 0.0 1.7 1 0 0 1 1 1 1 TAFII55 protein conserved region ApoLp-III PF07464.11 EGF84026.1 - 0.0043 17.1 3.0 0.013 15.6 3.0 1.8 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DNA_repr_REX1B PF14966.6 EGF84026.1 - 0.085 13.5 0.5 0.24 12.1 0.4 1.7 1 1 0 1 1 1 0 DNA repair REX1-B RR_TM4-6 PF06459.12 EGF84026.1 - 9.5 6.0 17.0 20 4.9 17.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PTH2 PF01981.16 EGF84027.1 - 8.9e-34 116.3 0.5 1.5e-33 115.5 0.5 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Nucleotid_trans PF03407.16 EGF84028.1 - 1.2e-17 64.6 0.0 3.1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Branch PF02485.21 EGF84028.1 - 2.4e-16 60.0 1.7 4.1e-16 59.2 1.7 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Pkinase PF00069.25 EGF84029.1 - 8.2e-24 84.4 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84029.1 - 1e-10 41.4 0.0 4.4e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 EGF84029.1 - 0.12 12.5 0.3 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Uteroglobin PF01099.17 EGF84029.1 - 0.13 12.6 0.0 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 Uteroglobin family Hexapep PF00132.24 EGF84030.1 - 1.1e-08 34.5 10.2 5.4e-05 22.7 3.6 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGF84030.1 - 5.4e-06 26.9 0.0 8.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EGF84030.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EGF84030.1 - 9.6e-05 20.7 1.2 0.00017 19.9 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGF84030.1 - 0.0032 16.5 6.5 0.048 12.6 0.4 2.4 2 1 1 3 3 3 2 L-fucokinase Ion_trans PF00520.31 EGF84031.1 - 1.5e-09 37.5 4.0 1.7e-09 37.3 4.0 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGF84031.1 - 1.8e-05 23.6 4.3 2e-05 23.5 4.3 1.1 1 0 0 1 1 1 1 Polycystin cation channel DUF4070 PF13282.6 EGF84031.1 - 0.049 13.7 0.2 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4070) DUF2818 PF10993.8 EGF84031.1 - 0.08 13.5 3.7 0.16 12.5 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2818) DUF2101 PF09874.9 EGF84031.1 - 0.19 11.4 4.8 0.058 13.1 1.8 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2101) ORC4_C PF14629.6 EGF84032.1 - 1e-36 126.4 0.0 1.6e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 EGF84032.1 - 0.00071 20.0 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGF84032.1 - 0.0035 17.3 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGF84032.1 - 0.0093 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF84032.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain 2OG-FeII_Oxy_2 PF13532.6 EGF84033.1 - 3.7e-23 82.7 0.0 6.3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EGF84033.1 - 5.4e-07 29.6 2.2 1e-06 28.7 2.2 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF1296 PF06972.11 EGF84033.1 - 0.0066 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) MFS_1 PF07690.16 EGF84034.1 - 2e-38 132.2 54.9 2.5e-34 118.8 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF84034.1 - 2.1e-11 43.4 4.5 2.1e-11 43.4 4.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EGF84035.1 - 9.3e-28 97.2 31.4 9.3e-28 97.2 31.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSF73-100_C PF11718.8 EGF84036.1 - 2.6e-34 118.7 0.1 4.7e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGF84036.1 - 4.9e-31 107.3 0.0 1.3e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EGF84036.1 - 1.1e-23 84.2 0.2 2e-23 83.5 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGF84036.1 - 2.9e-21 75.8 0.0 2.4e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EGF84036.1 - 3e-15 55.9 0.0 8e-15 54.5 0.0 1.8 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EGF84036.1 - 6.6e-09 35.6 0.1 1.8e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGF84036.1 - 2.6e-07 30.7 0.0 2.3e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGF84036.1 - 0.028 13.7 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative beta-lactamase-like family Pkinase PF00069.25 EGF84037.1 - 7.6e-34 117.3 0.0 3.2e-12 46.4 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84037.1 - 1.4e-16 60.6 0.0 2.5e-12 46.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGF84037.1 - 6.1e-05 22.5 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGF84037.1 - 0.00048 19.5 0.1 0.00079 18.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF84037.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AMP-binding PF00501.28 EGF84038.1 - 1.6e-61 208.2 0.0 2.1e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme XPG_N PF00752.17 EGF84039.1 - 2.1e-24 85.9 0.0 3.9e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGF84039.1 - 5.8e-24 84.3 0.0 1.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGF84039.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 EGF84039.1 - 0.044 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Tim17 PF02466.19 EGF84040.1 - 5.3e-15 55.8 0.2 9.3e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 EGF84041.1 - 1.2e-61 204.7 8.9 2.4e-22 78.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Baculo_VP1054 PF05789.11 EGF84041.1 - 0.013 14.7 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus VP1054 protein Tim17 PF02466.19 EGF84041.1 - 0.079 13.3 1.9 1.4 9.3 0.9 2.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family zf-C2H2 PF00096.26 EGF84042.1 - 4.1e-13 49.0 6.0 3.6e-07 30.3 2.5 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGF84042.1 - 6.9e-09 35.7 7.0 0.00016 21.9 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF84042.1 - 1.7e-08 34.6 6.5 3.4e-05 24.3 1.6 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGF84042.1 - 8.4e-08 32.0 4.4 1.6e-05 24.7 1.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGF84042.1 - 0.00013 21.8 6.5 0.056 13.4 1.0 2.4 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 EGF84042.1 - 0.00027 21.1 0.6 0.00027 21.1 0.6 1.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 EGF84042.1 - 0.0038 17.2 2.7 0.012 15.6 0.4 2.1 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_aberr PF17017.5 EGF84042.1 - 0.045 13.9 0.1 0.067 13.3 0.0 1.4 1 1 0 1 1 1 0 Aberrant zinc-finger FYVE PF01363.21 EGF84042.1 - 0.12 12.5 6.4 0.89 9.7 0.7 2.1 1 1 0 2 2 2 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 EGF84042.1 - 0.16 12.7 1.6 4.1 8.1 0.1 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 EGF84042.1 - 0.16 11.7 10.0 0.2 11.5 3.5 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 EGF84042.1 - 0.22 11.8 1.9 0.32 11.3 1.2 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 EGF84042.1 - 0.23 11.2 6.5 0.82 9.5 0.5 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 EGF84042.1 - 1.4 8.9 9.8 0.79 9.7 2.0 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Fcf1 PF04900.12 EGF84044.1 - 7.6e-38 128.9 2.9 1.5e-37 128.0 2.9 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EGF84044.1 - 8.7e-12 45.4 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 PIN like domain EF-hand_14 PF17959.1 EGF84044.1 - 0.035 14.5 0.1 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain adh_short PF00106.25 EGF84046.1 - 4.7e-39 133.9 5.0 4e-38 130.8 5.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGF84046.1 - 4e-22 78.9 3.4 2.9e-20 72.8 3.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGF84046.1 - 7.4e-08 32.5 3.0 3.3e-05 23.9 1.0 2.2 1 1 1 2 2 2 2 KR domain DUF1776 PF08643.10 EGF84046.1 - 0.00041 19.8 0.2 0.0012 18.3 0.1 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 EGF84046.1 - 0.0047 16.3 0.2 0.0092 15.3 0.2 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 EGF84046.1 - 0.051 13.8 0.2 0.12 12.7 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain Eno-Rase_NADH_b PF12242.8 EGF84046.1 - 0.11 12.3 1.2 0.29 10.9 0.2 2.2 1 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 EGF84046.1 - 0.13 11.7 0.1 3.6 7.0 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ribosomal_L29e PF01779.17 EGF84047.1 - 2.6e-20 72.4 15.4 3.4e-20 72.1 15.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family CLTH PF10607.9 EGF84048.1 - 6.9e-36 123.4 3.7 1.5e-35 122.3 3.7 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Zmiz1_N PF18028.1 EGF84048.1 - 0.022 15.1 0.2 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain TFIID_NTD2 PF04494.15 EGF84048.1 - 0.043 14.0 1.5 0.087 13.1 0.2 2.1 2 1 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain TPR_14 PF13428.6 EGF84049.1 - 6.3e-13 48.4 2.7 0.013 16.2 0.0 5.9 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGF84049.1 - 5.2e-12 45.0 2.9 0.0031 17.3 0.3 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGF84049.1 - 4.1e-11 42.4 8.5 0.062 13.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGF84049.1 - 7.6e-11 41.5 2.6 0.0089 15.7 0.1 5.1 3 2 2 5 5 5 2 TPR repeat TPR_20 PF14561.6 EGF84049.1 - 2.5e-08 34.1 2.2 0.018 15.3 0.0 4.0 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF84049.1 - 2.7e-08 33.3 12.2 0.47 10.7 0.2 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGF84049.1 - 1.2e-07 31.4 2.5 11 6.5 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF84049.1 - 7.2e-06 26.4 4.8 0.022 15.2 0.2 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF84049.1 - 5.5e-05 23.4 4.6 0.049 13.9 0.9 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF84049.1 - 0.00012 22.2 5.5 0.00044 20.4 1.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGF84049.1 - 0.00026 21.6 4.1 0.019 15.6 0.1 4.1 2 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF84049.1 - 0.001 18.9 5.1 0.77 9.9 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGF84049.1 - 0.0093 16.1 2.1 1.8 8.8 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGF84049.1 - 0.046 13.8 0.2 0.85 9.7 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Guanylate_cyc PF00211.20 EGF84051.1 - 2.2e-64 216.4 0.0 4.8e-64 215.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EGF84051.1 - 4.5e-13 49.3 0.2 2.2e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGF84051.1 - 2.1e-11 43.8 0.0 1.5e-10 41.1 0.0 2.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGF84051.1 - 3.1e-06 27.4 0.1 1.1e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 PAS fold HNOBA PF07701.14 EGF84051.1 - 6.4e-05 22.5 1.2 6.4e-05 22.5 1.2 3.6 3 1 0 3 3 3 1 Heme NO binding associated PAS_8 PF13188.7 EGF84051.1 - 0.0006 19.8 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain Sel1 PF08238.12 EGF84052.1 - 4.5e-29 100.2 17.9 1.3e-05 25.7 0.9 7.4 8 0 0 8 8 8 5 Sel1 repeat ANAPC3 PF12895.7 EGF84052.1 - 0.3 11.3 6.1 0.097 12.9 2.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGF84052.1 - 2.4 8.5 7.9 6.3 7.2 1.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGF84052.1 - 7.1 6.6 7.4 32 4.5 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP_bind_1 PF03029.17 EGF84053.1 - 2.5e-88 295.9 0.4 2.8e-88 295.8 0.4 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EGF84053.1 - 0.00046 19.6 1.2 0.0088 15.4 0.1 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EGF84053.1 - 0.00077 19.2 0.0 0.0024 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EGF84053.1 - 0.001 18.9 0.0 0.06 13.1 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop G-alpha PF00503.20 EGF84053.1 - 0.0016 17.7 0.1 0.51 9.4 0.1 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 EGF84053.1 - 0.0036 17.0 0.1 0.25 11.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EGF84053.1 - 0.0065 16.8 0.4 1.4 9.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 EGF84053.1 - 0.0085 15.7 0.1 1.9 8.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGF84053.1 - 0.017 15.4 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGF84053.1 - 0.028 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EGF84053.1 - 0.03 13.5 1.4 0.062 12.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 EGF84053.1 - 0.034 14.5 0.0 0.12 12.7 0.0 1.9 3 0 0 3 3 2 0 AAA ATPase domain AAA_14 PF13173.6 EGF84053.1 - 0.044 13.8 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGF84053.1 - 0.059 13.9 0.0 0.13 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGF84053.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF84053.1 - 0.079 12.9 0.5 12 5.7 0.0 3.3 2 1 2 4 4 4 0 RsgA GTPase NTPase_1 PF03266.15 EGF84053.1 - 0.1 12.5 0.1 15 5.5 0.0 2.8 2 1 1 3 3 3 0 NTPase ABC_tran PF00005.27 EGF84053.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EGF84053.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGF84053.1 - 0.11 11.9 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 EGF84053.1 - 0.11 12.2 0.8 15 5.4 0.1 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGF84053.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGF84053.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 EGF84053.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 EGF84053.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EGF84053.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase ATG101 PF07855.12 EGF84054.1 - 7e-25 87.8 4.0 1.8e-16 60.5 1.1 2.2 1 1 1 2 2 2 2 Autophagy-related protein 101 AD PF09793.9 EGF84055.1 - 6.8e-26 90.2 0.0 9.8e-26 89.7 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 EGF84055.1 - 0.079 12.5 0.1 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Gemin6 protein Pkinase PF00069.25 EGF84056.1 - 1.2e-70 237.9 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84056.1 - 6.8e-35 120.6 0.0 9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF84056.1 - 7.5e-05 22.2 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGF84056.1 - 0.012 15.3 0.1 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AAA PF00004.29 EGF84057.1 - 2.4e-18 66.8 0.0 4.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGF84057.1 - 3e-16 59.6 0.0 7e-15 55.2 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGF84057.1 - 5e-16 58.9 0.0 8.8e-13 48.3 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EGF84057.1 - 3.3e-08 33.7 0.0 3.5e-07 30.3 0.0 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EGF84057.1 - 4.7e-06 26.5 0.1 7.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 EGF84057.1 - 1.7e-05 24.6 0.0 3.9e-05 23.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 EGF84057.1 - 2.7e-05 23.4 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGF84057.1 - 4.6e-05 23.7 0.4 0.045 14.0 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF84057.1 - 5.4e-05 23.0 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGF84057.1 - 8.8e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGF84057.1 - 0.00012 22.6 0.0 0.00031 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EGF84057.1 - 0.00014 22.1 0.0 0.00044 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 EGF84057.1 - 0.00014 21.7 0.0 0.0016 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGF84057.1 - 0.00044 20.0 0.0 0.00094 19.0 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EGF84057.1 - 0.00047 19.7 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 EGF84057.1 - 0.00049 19.9 0.1 0.0037 17.1 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase TPR_6 PF13174.6 EGF84057.1 - 0.0012 19.4 0.4 0.61 10.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_19 PF13245.6 EGF84057.1 - 0.0019 18.5 0.1 0.078 13.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 EGF84057.1 - 0.0029 17.6 0.0 0.36 10.8 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EGF84057.1 - 0.0032 17.5 0.2 0.038 14.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 EGF84057.1 - 0.0041 16.6 0.0 0.051 13.0 0.0 2.3 1 1 0 1 1 1 1 Bacterial TniB protein Viral_helicase1 PF01443.18 EGF84057.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EGF84057.1 - 0.025 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF84057.1 - 0.026 15.1 0.0 0.29 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGF84057.1 - 0.038 13.7 0.2 0.11 12.3 0.0 1.8 2 1 0 2 2 1 0 IstB-like ATP binding protein PhoH PF02562.16 EGF84057.1 - 0.049 13.1 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 EGF84057.1 - 0.073 12.4 0.0 0.88 8.9 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGF84057.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 EGF84057.1 - 0.091 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea XPG_I PF00867.18 EGF84058.1 - 2.9e-26 91.6 0.0 5.3e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGF84058.1 - 4.5e-19 68.8 0.1 9.6e-19 67.7 0.0 1.6 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EGF84058.1 - 8.6e-05 22.1 0.0 0.00024 20.7 0.0 1.8 1 1 0 1 1 1 1 XPG domain containing DHFR_1 PF00186.19 EGF84058.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Dihydrofolate reductase Cofilin_ADF PF00241.20 EGF84059.1 - 1e-23 83.4 0.1 1.2e-23 83.2 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ets PF00178.22 EGF84059.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Ets-domain Kelch_4 PF13418.6 EGF84060.1 - 2.4e-35 120.3 6.6 1.2e-08 34.9 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGF84060.1 - 2e-30 104.2 2.3 2.8e-07 30.4 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGF84060.1 - 2.1e-30 104.4 5.0 2.9e-08 33.8 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGF84060.1 - 2e-23 81.8 7.5 0.00043 20.5 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGF84060.1 - 3.5e-23 80.6 9.5 3.1e-05 23.7 0.1 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EGF84060.1 - 1.1e-19 69.7 7.4 1.7e-05 24.3 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Trypan_PARP PF05887.11 EGF84060.1 - 0.41 10.6 3.9 0.47 10.4 0.2 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FtsA PF14450.6 EGF84061.1 - 7.6 7.0 5.9 31 5.1 5.6 2.2 1 1 0 1 1 1 0 Cell division protein FtsA Glutaredoxin PF00462.24 EGF84062.1 - 1.3e-38 131.0 0.1 8.9e-19 67.5 0.0 3.3 4 0 0 4 4 4 2 Glutaredoxin Thioredoxin PF00085.20 EGF84062.1 - 1.1e-09 38.2 0.0 2.4e-08 33.9 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin SH3BGR PF04908.15 EGF84062.1 - 0.0015 18.6 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Thioredoxin_8 PF13905.6 EGF84062.1 - 0.014 15.7 0.1 1.4 9.3 0.0 3.1 3 1 1 4 4 4 0 Thioredoxin-like HyaE PF07449.11 EGF84062.1 - 0.052 13.5 0.0 0.31 11.0 0.0 2.4 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE RdRP PF05183.12 EGF84062.1 - 0.052 12.2 0.0 4.8 5.7 0.0 2.0 1 1 1 2 2 2 0 RNA dependent RNA polymerase GST_N_3 PF13417.6 EGF84062.1 - 0.11 12.9 0.0 8 7.0 0.0 3.1 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain Dpy-30 PF05186.13 EGF84063.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Dpy-30 motif UPF0113_N PF17833.1 EGF84064.1 - 2.1e-32 111.5 0.1 3.1e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGF84064.1 - 1.3e-23 83.0 0.0 4.9e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 UPF0113 PUA domain PP1 PF07430.11 EGF84064.1 - 0.0094 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Phloem filament protein PP1 cystatin-like domain KIAA1430 PF13879.6 EGF84065.1 - 1e-23 84.0 9.6 1e-23 84.0 9.6 3.8 3 2 0 3 3 3 1 KIAA1430 homologue JAB PF01398.21 EGF84066.1 - 5.9e-33 113.3 0.3 1.2e-32 112.3 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGF84066.1 - 8.4e-13 48.7 0.8 8.4e-13 48.7 0.8 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGF84066.1 - 9.2e-07 28.6 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-RING_2 PF13639.6 EGF84067.1 - 0.0015 18.8 5.4 0.0015 18.8 5.4 2.4 1 1 1 2 2 2 1 Ring finger domain PHD PF00628.29 EGF84067.1 - 0.5 10.3 17.7 0.092 12.7 4.7 2.5 1 1 1 2 2 2 0 PHD-finger PHD_4 PF16866.5 EGF84067.1 - 9.4 6.4 14.3 1.4 9.1 2.6 2.8 1 1 0 2 2 2 0 PHD-finger GTP_EFTU PF00009.27 EGF84068.1 - 8.7e-34 116.8 1.9 8.7e-34 116.8 1.9 3.4 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGF84068.1 - 4.6e-29 100.6 2.8 1.6e-28 98.9 1.4 2.6 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGF84068.1 - 5e-10 39.5 0.1 1.4e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGF84068.1 - 1.6e-06 27.9 1.3 0.00012 21.9 0.5 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 RsgA_GTPase PF03193.16 EGF84068.1 - 0.00016 21.6 1.0 0.58 10.0 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 EGF84068.1 - 0.00021 20.8 0.1 0.00078 19.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B IF2_N PF04760.15 EGF84068.1 - 0.00033 20.4 0.6 0.00099 18.9 0.1 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 EGF84068.1 - 0.00033 21.0 9.7 0.00065 20.0 0.2 3.9 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MeaB PF03308.16 EGF84068.1 - 0.0025 16.9 0.2 0.012 14.7 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EGF84068.1 - 0.0057 16.9 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGF84068.1 - 0.0087 15.5 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGF84068.1 - 0.15 11.8 1.0 0.41 10.4 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EGF84068.1 - 0.38 10.8 7.2 2.9 7.9 0.0 3.8 3 1 1 4 4 4 0 Dynamin family DUF4956 PF16316.5 EGF84068.1 - 0.66 9.6 3.7 0.55 9.9 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) CTP_transf_like PF01467.26 EGF84070.1 - 3.9e-45 153.6 0.1 5.2e-27 94.8 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EGF84070.1 - 1.3e-06 28.3 0.7 0.017 15.0 0.3 3.0 3 0 0 3 3 3 2 FAD synthetase Pantoate_ligase PF02569.15 EGF84070.1 - 0.0098 15.1 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 1 Pantoate-beta-alanine ligase HIGH_NTase1 PF05636.11 EGF84070.1 - 0.15 11.3 0.1 4.1 6.5 0.0 2.1 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase Arv1 PF04161.13 EGF84071.1 - 0.14 12.3 1.0 0.15 12.2 1.0 1.1 1 0 0 1 1 1 0 Arv1-like family A_deamin PF02137.18 EGF84072.1 - 7.6e-61 206.4 1.4 1.1e-60 205.8 1.4 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF4675 PF15720.5 EGF84072.1 - 0.054 13.3 3.7 0.11 12.3 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Ribophorin_II PF05817.14 EGF84073.1 - 5.9e-48 163.9 1.5 7.5e-48 163.5 1.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4399 PF14347.6 EGF84073.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4399) Histone_H2A_C PF16211.5 EGF84074.1 - 2.8e-20 71.7 2.7 4.5e-20 71.1 2.7 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGF84074.1 - 5.9e-16 59.0 0.0 7.4e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF84074.1 - 6.1e-06 26.4 0.0 7.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MCM PF00493.23 EGF84075.1 - 5.4e-81 271.0 0.3 1.9e-78 262.6 0.3 2.3 1 1 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGF84075.1 - 7e-27 93.7 3.3 1.3e-26 92.8 3.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EGF84075.1 - 8.7e-24 83.8 0.5 1.6e-23 83.0 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EGF84075.1 - 2.3e-08 33.7 0.0 1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGF84075.1 - 1.5e-06 28.2 0.0 3.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGF84075.1 - 2.3e-05 24.2 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cobl PF09469.10 EGF84075.1 - 0.019 15.2 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain RuvB_N PF05496.12 EGF84075.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGF84075.1 - 0.069 13.5 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGF84075.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L5 PF00281.19 EGF84076.1 - 0.029 14.7 0.1 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L5 FKBP26_C PF18046.1 EGF84076.1 - 0.035 14.2 0.2 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 FKBP26_C-terminal DLIC PF05783.11 EGF84077.1 - 6.8e-58 196.6 9.0 8.7e-53 179.8 0.8 3.9 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) 7tm_3 PF00003.22 EGF84078.1 - 1.6e-12 47.6 23.7 3.4e-12 46.6 23.7 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 EGF84078.1 - 9.5e-10 38.1 2.0 5.9e-09 35.5 2.1 2.1 1 1 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.25 EGF84080.1 - 9.2e-59 198.9 0.0 1.8e-58 198.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84080.1 - 3.6e-26 92.0 0.0 5.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF84080.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGF84080.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF84080.1 - 0.11 11.4 0.2 0.47 9.3 0.1 1.9 2 0 0 2 2 2 0 Haspin like kinase domain KA1 PF02149.19 EGF84080.1 - 0.16 11.8 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Kinase associated domain 1 RGS PF00615.19 EGF84081.1 - 4.3e-24 85.1 0.1 1.1e-23 83.8 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS_DHEX PF18148.1 EGF84081.1 - 3.6e-13 49.5 0.1 8e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain DEP PF00610.21 EGF84081.1 - 3.5e-10 39.8 0.1 8e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) G-gamma PF00631.22 EGF84081.1 - 3e-06 27.2 0.3 2.3e-05 24.3 0.2 2.3 2 0 0 2 2 2 1 GGL domain DELLA PF12041.8 EGF84081.1 - 0.097 12.6 0.2 23 5.0 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulator DELLA protein N terminal RRM_1 PF00076.22 EGF84082.1 - 3.3e-28 97.3 0.1 6.6e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGF84082.1 - 2.7e-08 33.5 0.0 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGF84082.1 - 0.00014 21.7 0.0 0.0054 16.6 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Clat_adaptor_s PF01217.20 EGF84083.1 - 1.4e-51 174.1 2.8 1.7e-51 173.9 2.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain E1-E2_ATPase PF00122.20 EGF84084.1 - 3.3e-45 153.8 5.3 3.3e-45 153.8 5.3 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGF84084.1 - 1.2e-35 122.8 8.6 1.2e-35 122.8 8.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGF84084.1 - 2.1e-25 90.3 0.9 2.5e-24 86.7 0.9 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGF84084.1 - 3.6e-14 52.2 0.0 1.3e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGF84084.1 - 2.3e-07 30.8 0.0 5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGF84084.1 - 2.1e-06 27.7 1.9 0.00012 21.9 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGF84084.1 - 0.015 15.7 0.0 0.041 14.3 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Abhydro_lipase PF04083.16 EGF84084.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Kinesin PF00225.23 EGF84085.1 - 8.1e-111 370.1 0.1 9e-111 370.0 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGF84085.1 - 8.4e-27 93.9 0.1 1.4e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Microtubule binding RNase_HII PF01351.18 EGF84086.1 - 7.5e-54 182.6 0.0 1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII DUF1874 PF08960.10 EGF84086.1 - 0.054 13.6 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) Septin PF00735.18 EGF84087.1 - 8.2e-120 399.3 0.0 8.2e-120 399.3 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGF84087.1 - 2.2e-07 30.9 0.0 5.7e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGF84087.1 - 7.4e-06 26.0 3.3 4.2e-05 23.5 0.1 2.9 3 1 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EGF84087.1 - 0.00011 22.7 1.2 0.016 15.7 0.0 3.1 2 1 1 3 3 3 1 ABC transporter AIG1 PF04548.16 EGF84087.1 - 0.00086 18.7 0.6 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EGF84087.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 2.3 2 2 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EGF84087.1 - 0.0036 16.9 3.7 0.024 14.2 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGF84087.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGF84087.1 - 0.0078 16.5 0.1 0.039 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGF84087.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 EGF84087.1 - 0.028 13.9 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 EGF84087.1 - 0.089 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Ras PF00071.22 EGF84087.1 - 0.092 12.3 0.8 0.26 10.9 0.0 2.2 2 1 0 2 2 2 0 Ras family Roc PF08477.13 EGF84087.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGF84087.1 - 0.19 11.1 2.3 0.61 9.4 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Strep_SA_rep PF06696.11 EGF84087.1 - 0.39 10.8 10.9 0.078 13.0 3.5 2.7 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Atg14 PF10186.9 EGF84087.1 - 0.55 9.3 4.4 0.85 8.6 4.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EGF84087.1 - 1 8.9 5.4 1.7 8.2 5.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3987 PF13148.6 EGF84087.1 - 1.1 8.1 6.0 20 4.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) UPF0242 PF06785.11 EGF84087.1 - 1.9 8.5 9.4 3.1 7.8 9.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADH_zinc_N PF00107.26 EGF84088.1 - 3.1e-15 56.3 0.0 5.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGF84088.1 - 2.6e-07 30.5 0.0 5.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGF84088.1 - 0.00055 21.0 0.0 0.0012 19.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding_2 PF13380.6 EGF84088.1 - 0.0032 18.0 0.2 0.83 10.2 0.1 2.4 1 1 1 2 2 2 2 CoA binding domain ADH_N_2 PF16884.5 EGF84088.1 - 0.0038 17.1 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase NmrA PF05368.13 EGF84088.1 - 0.086 12.4 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family IFT81_CH PF18383.1 EGF84089.1 - 7.9e-20 71.4 0.5 7.9e-20 71.4 0.5 3.3 3 1 1 4 4 4 1 Intraflagellar transport 81 calponin homology domain ATG16 PF08614.11 EGF84089.1 - 0.012 15.8 9.4 0.012 15.8 9.4 4.6 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EGF84089.1 - 1.2 7.9 60.1 0.053 12.4 8.8 5.0 1 1 4 5 5 5 0 Spc7 kinetochore protein kleA_kleC PF17383.2 EGF84089.1 - 2.1 8.7 16.5 5.9 7.3 0.1 5.5 4 1 2 6 6 6 0 Uncharacterized KorC regulated protein A Syja_N PF02383.18 EGF84090.1 - 3.6e-75 253.3 0.0 5.1e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain RRM_1 PF00076.22 EGF84092.1 - 5.1e-20 71.1 0.0 7.3e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGF84092.1 - 8.6e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 EGF84092.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif PseudoU_synth_2 PF00849.22 EGF84093.1 - 4.5e-31 108.1 0.0 6.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGF84093.1 - 0.089 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 S4 domain ubiquitin PF00240.23 EGF84094.1 - 3.3e-34 116.5 1.2 4.6e-34 116.0 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGF84094.1 - 8e-26 89.9 1.8 1.7e-25 88.9 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGF84094.1 - 5.1e-16 58.3 0.6 1.1e-15 57.2 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGF84094.1 - 2.6e-05 24.6 0.2 0.00019 21.8 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGF84094.1 - 0.00098 19.2 0.4 0.0024 18.0 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGF84094.1 - 0.0084 16.4 0.4 0.018 15.4 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGF84094.1 - 0.0092 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGF84094.1 - 0.018 15.6 0.6 0.029 14.9 0.6 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain IBR PF01485.21 EGF84094.1 - 0.028 14.6 0.2 0.047 13.9 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 EGF84094.1 - 0.033 14.2 1.1 7.3 6.7 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Fer2_3 PF13085.6 EGF84094.1 - 0.05 13.6 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Stig1 PF04885.13 EGF84094.1 - 0.12 12.9 1.7 0.19 12.2 1.7 1.4 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 DUF202 PF02656.15 EGF84095.1 - 0.18 12.3 11.2 0.97 9.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF996 PF06195.13 EGF84095.1 - 0.57 10.5 7.6 0.074 13.3 3.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF996) UCH PF00443.29 EGF84097.1 - 0.00053 19.6 1.8 0.00053 19.6 1.8 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Whi5 PF08528.11 EGF84097.1 - 0.028 14.0 0.1 0.065 12.9 0.1 1.7 1 0 0 1 1 1 0 Whi5 like S4 PF01479.25 EGF84098.1 - 1.1e-08 34.6 0.0 1.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EGF84098.1 - 0.0048 16.7 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 S4 domain ThiS PF02597.20 EGF84098.1 - 0.15 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 ThiS family SGT1 PF07093.11 EGF84099.1 - 2.5e-135 452.2 4.6 2.9e-135 452.0 4.6 1.0 1 0 0 1 1 1 1 SGT1 protein Cyclin PF08613.11 EGF84101.1 - 2.6e-09 37.7 0.9 5.4e-09 36.6 0.9 1.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGF84101.1 - 0.0062 16.3 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain E1_dh PF00676.20 EGF84102.1 - 4.4e-65 219.6 0.0 6.3e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 EGF84102.1 - 1.5e-63 213.7 0.0 2.4e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGF84102.1 - 2.7e-37 127.8 0.0 1.1e-27 96.6 0.0 3.3 3 0 0 3 3 3 2 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGF84102.1 - 2.6e-18 65.3 1.2 2.6e-18 65.3 1.2 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Ribosomal_S10 PF00338.22 EGF84103.1 - 7.9e-22 77.3 0.1 8.7e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MEA1 PF06910.11 EGF84104.1 - 0.00035 21.2 7.9 0.00044 20.9 5.0 2.2 2 1 0 2 2 2 1 Male enhanced antigen 1 (MEA1) SLATT_5 PF18160.1 EGF84104.1 - 0.25 10.7 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3395 PF11875.8 EGF84105.1 - 2.6e-42 144.4 0.1 5.2e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EGF84105.1 - 1.6e-20 72.9 1.3 3.5e-20 71.9 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain SEF14_adhesin PF06443.11 EGF84105.1 - 0.021 14.7 0.3 0.044 13.7 0.3 1.5 1 0 0 1 1 1 0 SEF14-like adhesin CLP1_P PF16575.5 EGF84106.1 - 6.1e-37 127.2 0.0 1.2e-36 126.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 EGF84106.1 - 0.027 14.4 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGF84106.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGF84106.1 - 0.042 14.3 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 EGF84106.1 - 0.042 13.9 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGF84106.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGF84106.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 EGF84107.1 - 2.3e-35 122.1 0.0 4.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGF84107.1 - 2e-22 79.8 0.0 3.8e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 EGF84107.1 - 1.4e-07 31.2 0.2 2.2e-05 24.1 0.3 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGF84107.1 - 0.0051 17.2 0.1 11 6.6 0.1 4.0 1 1 4 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF84107.1 - 0.016 15.7 0.1 85 4.3 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat HEM4 PF02602.15 EGF84109.1 - 4.6e-32 111.2 0.0 5.6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD GRASP55_65 PF04495.14 EGF84110.1 - 3.3e-53 179.7 0.0 5.4e-43 146.6 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EGF84110.1 - 1.4e-07 31.2 0.0 0.00063 19.5 0.0 3.0 3 1 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EGF84110.1 - 2.4e-07 31.0 0.0 0.00094 19.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EGF84110.1 - 0.00071 19.5 0.2 0.35 10.9 0.0 2.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain Membralin PF09746.9 EGF84110.1 - 2.4 7.1 5.9 3.2 6.7 5.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein Ribosomal_S9 PF00380.19 EGF84111.1 - 1.8e-39 135.0 0.2 2e-39 134.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LRR_4 PF12799.7 EGF84112.1 - 0.00034 20.9 0.4 6 7.4 0.1 4.3 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EGF84112.1 - 0.0062 16.4 0.1 0.02 14.8 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGF84112.1 - 0.02 14.8 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like Gemini_AL3 PF01407.17 EGF84112.1 - 0.072 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Geminivirus AL3 protein Pkinase PF00069.25 EGF84113.1 - 1.3e-70 237.7 0.0 1.6e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84113.1 - 1.6e-35 122.6 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGF84113.1 - 1.8e-05 23.8 0.1 0.00095 18.2 0.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGF84113.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Mito_carr PF00153.27 EGF84114.1 - 8.2e-64 211.6 3.1 3.8e-21 74.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGF84114.1 - 0.16 11.1 0.5 2.1 7.4 0.1 3.0 2 1 0 2 2 2 0 Gammaproteobacterial serine protease ELFV_dehydrog_N PF02812.18 EGF84115.1 - 7.5e-54 181.1 0.0 1.3e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EGF84115.1 - 4.5e-52 177.2 0.1 2.4e-51 174.8 0.0 1.9 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EGF84115.1 - 0.024 14.0 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EGF84115.1 - 0.087 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_C97 PF05903.14 EGF84116.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain TxDE PF18711.1 EGF84116.1 - 0.16 12.1 0.4 0.55 10.4 0.4 1.9 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme PB1 PF00564.24 EGF84118.1 - 0.021 14.7 0.0 0.079 12.9 0.0 2.0 2 1 1 3 3 3 0 PB1 domain Rap_GAP PF02145.15 EGF84119.1 - 3.3e-60 202.8 0.0 9.2e-60 201.4 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP LIM PF00412.22 EGF84119.1 - 3.6e-08 33.5 1.2 8e-08 32.4 1.2 1.6 1 0 0 1 1 1 1 LIM domain PK PF00224.21 EGF84121.1 - 4.2e-141 469.8 5.0 6.1e-141 469.3 5.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGF84121.1 - 1e-30 106.3 2.2 3e-30 104.9 2.2 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGF84121.1 - 0.0054 15.9 0.1 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RIIa PF02197.17 EGF84122.1 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Mito_carr PF00153.27 EGF84123.1 - 9.1e-72 237.1 1.9 5e-27 93.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein YgbA_NO PF11756.8 EGF84123.1 - 0.034 14.5 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter Pkinase PF00069.25 EGF84124.1 - 9.1e-29 100.6 0.0 1.1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84124.1 - 2.9e-14 53.0 0.0 3.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF84124.1 - 1.8e-05 23.7 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGF84124.1 - 0.0041 16.5 0.0 0.006 16.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGF84124.1 - 0.0053 16.7 0.0 2.3 8.0 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family ABC1 PF03109.16 EGF84124.1 - 0.045 13.9 0.1 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 EGF84124.1 - 0.13 11.5 0.0 4.8 6.4 0.0 2.1 1 1 0 1 1 1 0 Kinase-like Phosducin PF02114.16 EGF84125.1 - 4.2e-16 58.7 0.1 5.1e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGF84125.1 - 9.1e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PTB PF08416.13 EGF84125.1 - 0.19 11.9 1.2 0.28 11.4 0.2 1.7 2 0 0 2 2 2 0 Phosphotyrosine-binding domain DUF745 PF05335.13 EGF84126.1 - 0.014 15.2 4.2 0.018 14.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMF_TATA_bd PF12325.8 EGF84126.1 - 0.032 14.4 13.6 1.2 9.4 6.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EGF84126.1 - 0.057 12.7 7.2 1.3 8.3 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 EGF84126.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 GrpE PF01025.19 EGF84126.1 - 0.21 11.3 7.5 0.41 10.3 2.8 2.4 2 0 0 2 2 2 0 GrpE SlyX PF04102.12 EGF84126.1 - 0.34 11.5 5.1 0.13 12.9 0.6 2.3 2 0 0 2 2 2 0 SlyX SKA1 PF07160.12 EGF84126.1 - 0.61 9.9 6.8 0.13 12.1 2.4 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF16 PF01519.16 EGF84126.1 - 3.4 8.2 7.0 23 5.5 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DHR10 PF18595.1 EGF84126.1 - 4.8 7.3 10.1 0.64 10.1 2.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Fzo_mitofusin PF04799.13 EGF84126.1 - 5 6.7 11.8 4.7 6.7 4.5 2.4 2 0 0 2 2 2 0 fzo-like conserved region FUR PF01475.19 EGF84127.1 - 0.023 14.8 0.1 0.053 13.7 0.1 1.6 1 0 0 1 1 1 0 Ferric uptake regulator family EAP30 PF04157.16 EGF84128.1 - 6.7e-40 136.8 0.6 1.5e-39 135.7 0.3 1.7 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EGF84128.1 - 1.5e-19 69.9 0.0 3.6e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 EGF84128.1 - 2.1e-06 26.9 27.7 0.0019 17.4 2.7 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 EGF84128.1 - 0.022 14.1 1.4 0.022 14.1 1.4 4.1 4 0 0 4 4 4 0 zinc-ribbon domain PH_TFIIH PF08567.11 EGF84128.1 - 0.061 13.7 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain zf-met PF12874.7 EGF84128.1 - 0.12 12.8 8.8 4.3 7.9 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DZR PF12773.7 EGF84128.1 - 0.15 12.1 22.0 0.53 10.4 9.6 3.0 1 1 3 4 4 4 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 EGF84128.1 - 5 6.9 6.7 27 4.6 1.7 3.3 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Cyclin PF08613.11 EGF84129.1 - 6.3e-11 42.9 0.1 6.3e-11 42.9 0.1 2.5 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGF84129.1 - 9e-11 41.6 0.1 2.3e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_6 PF13516.6 EGF84130.1 - 0.0015 18.4 9.9 0.042 13.9 0.1 5.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 EGF84130.1 - 0.076 13.5 7.8 14 6.2 5.3 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGF84130.1 - 8.3 7.4 13.9 32 5.6 0.1 5.6 5 2 0 5 5 5 0 Leucine Rich Repeat MFS_1 PF07690.16 EGF84131.1 - 1.6e-29 103.0 45.4 1.6e-29 103.0 45.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGF84131.1 - 0.19 10.1 11.7 0.46 8.8 11.7 1.7 1 1 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 EGF84132.1 - 7.4e-35 120.5 73.9 8.2e-27 94.0 37.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EGF84133.1 - 1.5e-31 109.6 53.4 3.7e-31 108.4 46.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EGF84134.1 - 7.3e-32 110.7 54.8 1.6e-31 109.6 47.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.20 EGF84135.1 - 2.5e-76 257.2 0.0 3.1e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGF84135.1 - 0.047 12.8 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGF84135.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Thioredoxin PF00085.20 EGF84136.1 - 9.5e-29 99.4 0.1 1.3e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGF84136.1 - 2.7e-05 24.4 0.0 4.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EGF84136.1 - 0.00031 20.2 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGF84136.1 - 0.00033 21.1 0.9 0.0032 17.9 0.9 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGF84136.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGF84136.1 - 0.025 14.3 0.9 0.054 13.2 0.6 1.7 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 EGF84136.1 - 0.03 14.5 0.1 0.067 13.4 0.1 1.7 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EGF84136.1 - 0.032 14.0 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSHCT PF08148.12 EGF84139.1 - 2e-51 173.9 0.2 3.8e-51 173.0 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EGF84139.1 - 1.5e-17 64.0 0.0 4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 EGF84139.1 - 4.3e-11 43.3 0.2 4.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.31 EGF84139.1 - 3.2e-06 27.5 0.0 1.7e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF84139.1 - 7e-06 26.1 0.2 6.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 EGF84139.1 - 0.0067 15.6 0.3 0.01 15.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) AAA_22 PF13401.6 EGF84139.1 - 0.11 12.7 0.2 0.56 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Agenet PF05641.12 EGF84140.1 - 0.092 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Agenet domain Methyltransf_25 PF13649.6 EGF84141.1 - 7.8e-06 26.5 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF84141.1 - 0.00029 21.4 0.0 0.0008 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF84141.1 - 0.0016 19.2 0.5 0.011 16.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGF84141.1 - 0.0021 19.1 0.1 0.024 15.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF84141.1 - 0.035 13.9 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 EGF84141.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Copper-fist PF00649.18 EGF84142.1 - 7.4e-15 54.2 0.4 2.8e-14 52.3 0.4 2.1 1 0 0 1 1 1 1 Copper fist DNA binding domain Cyclin_N PF00134.23 EGF84142.1 - 0.21 11.3 0.5 0.52 10.1 0.5 1.7 1 0 0 1 1 1 0 Cyclin, N-terminal domain Opi1 PF08618.10 EGF84143.1 - 6.1e-27 94.9 13.2 1.5e-24 87.0 0.3 3.1 1 1 2 3 3 3 2 Transcription factor Opi1 Adap_comp_sub PF00928.21 EGF84144.1 - 3.3e-61 207.0 0.0 4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGF84144.1 - 0.0016 18.4 0.6 0.0016 18.4 0.6 1.7 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Mucin15 PF15672.5 EGF84144.1 - 0.16 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Phosphoesterase PF04185.14 EGF84145.1 - 6.5e-77 259.1 0.0 8e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family RhoGEF PF00621.20 EGF84146.1 - 1.1e-41 143.1 4.2 1.9e-41 142.3 4.2 1.4 1 0 0 1 1 1 1 RhoGEF domain EMC3_TMCO1 PF01956.16 EGF84146.1 - 0.067 12.9 1.3 0.12 12.1 1.3 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF749 PF05370.11 EGF84146.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF749) WD40_4 PF16300.5 EGF84149.1 - 1.1e-14 54.1 0.1 3e-14 52.6 0.1 1.8 2 0 0 2 2 2 1 Type of WD40 repeat DUF1899 PF08953.11 EGF84149.1 - 7.1e-12 45.0 1.3 1.1e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 EGF84149.1 - 1.6e-07 31.5 0.1 0.17 12.2 0.0 5.2 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGF84149.1 - 0.00013 22.7 7.8 3.1 8.8 0.0 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat FOP_dimer PF09398.10 EGF84150.1 - 1.2e-11 44.7 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 EGF84150.1 - 3.9e-09 35.4 0.2 6.2e-09 34.7 0.2 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 EGF84150.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 LisH Pyridoxal_deC PF00282.19 EGF84151.1 - 1.2e-19 70.3 0.0 1.7e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGF84151.1 - 8.3e-08 31.6 0.1 4.3e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGF84151.1 - 3e-05 23.5 0.8 6.7e-05 22.4 0.8 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGF84151.1 - 0.076 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Cmc1 PF08583.10 EGF84152.1 - 4.3e-09 36.3 2.4 5.5e-09 35.9 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EGF84152.1 - 0.0019 18.3 1.5 0.048 13.8 0.5 2.3 2 0 0 2 2 2 1 CHCH domain Metallophos PF00149.28 EGF84153.1 - 7.2e-37 127.9 0.6 1.2e-36 127.1 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGF84153.1 - 0.00069 20.0 0.1 0.002 18.5 0.1 1.7 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EGF84153.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CCDC92 PF14916.6 EGF84154.1 - 3.5e-13 49.1 1.0 8.3e-13 47.9 1.0 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DivIC PF04977.15 EGF84154.1 - 0.023 14.4 0.8 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Septum formation initiator Fungal_TACC PF12709.7 EGF84154.1 - 0.11 12.9 3.4 1.1 9.7 0.1 2.8 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 EGF84154.1 - 0.16 11.3 2.8 0.41 9.9 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 EGF84154.1 - 0.66 10.1 7.0 15 5.8 0.2 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation TBCC_N PF16752.5 EGF84154.1 - 1.8 9.1 5.8 0.73 10.3 1.1 2.7 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Tup_N PF08581.10 EGF84154.1 - 9.6 6.6 11.5 0.19 12.1 3.2 2.4 3 0 0 3 3 3 0 Tup N-terminal Arfaptin PF06456.13 EGF84155.1 - 1.2e-09 38.1 8.6 3.3e-09 36.7 8.6 1.7 1 1 0 1 1 1 1 Arfaptin-like domain DUF1957 PF09210.11 EGF84155.1 - 0.11 12.9 1.6 0.19 12.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) STAT_alpha PF01017.20 EGF84155.1 - 0.21 11.5 7.2 0.1 12.5 4.4 1.8 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF4298 PF14131.6 EGF84155.1 - 1 9.4 3.8 0.87 9.6 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) His_biosynth PF00977.21 EGF84158.1 - 6e-46 156.8 0.1 1.1e-44 152.7 0.1 2.7 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.28 EGF84158.1 - 2.5e-19 69.8 0.0 4.2e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EGF84158.1 - 3.8e-06 26.9 0.0 4.4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGF84158.1 - 0.00022 20.9 0.0 0.00046 19.8 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EGF84158.1 - 0.0088 15.8 0.0 0.055 13.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 F5_F8_type_C PF00754.25 EGF84159.1 - 3.4e-08 33.7 0.0 4.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 EGF84159.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 XRCC1 N terminal domain Sad1_UNC PF07738.13 EGF84159.1 - 0.0057 16.7 0.1 0.087 12.8 0.0 2.1 1 1 1 2 2 2 1 Sad1 / UNC-like C-terminal ANAPC10 PF03256.16 EGF84159.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Alk_phosphatase PF00245.20 EGF84160.1 - 1.2e-98 330.9 0.0 1.4e-98 330.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGF84160.1 - 0.0014 18.0 0.0 0.0036 16.7 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily TniQ PF06527.11 EGF84160.1 - 0.14 12.9 0.0 0.67 10.7 0.0 1.9 2 0 0 2 2 2 0 TniQ CLLAC PF15675.5 EGF84160.1 - 1.1 8.9 4.9 2.1 8.0 4.9 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain Histone_H2A_C PF16211.5 EGF84161.1 - 3.9e-19 68.1 2.8 6e-19 67.5 2.8 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGF84161.1 - 6.8e-16 58.8 0.0 8.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGF84161.1 - 6.9e-06 26.3 0.0 8.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ctr PF04145.15 EGF84162.1 - 3.1e-44 151.2 0.0 2.4e-43 148.3 0.0 2.3 2 1 0 2 2 2 1 Ctr copper transporter family CxC6 PF18721.1 EGF84162.1 - 0.008 16.4 1.2 0.023 15.0 1.2 1.8 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases MOLO1 PF17175.4 EGF84163.1 - 0.0027 17.8 0.6 0.0081 16.3 0.6 1.7 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 Memo PF01875.17 EGF84164.1 - 3.8e-81 272.2 0.0 4.4e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_S10 PF00338.22 EGF84165.1 - 6.9e-27 93.5 1.0 8.4e-27 93.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GRIP PF01465.20 EGF84166.1 - 5.9e-13 48.5 0.1 1.4e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 GRIP domain Fez1 PF06818.15 EGF84166.1 - 0.0012 19.4 21.7 0.0012 19.4 21.7 7.1 1 1 5 7 7 7 2 Fez1 Col_cuticle_N PF01484.17 EGF84166.1 - 0.057 13.5 0.1 3.2 7.9 0.0 3.3 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain TPR_5 PF12688.7 EGF84166.1 - 0.092 13.0 12.4 0.11 12.8 0.3 4.0 4 0 0 4 4 4 0 Tetratrico peptide repeat PAS_7 PF12860.7 EGF84166.1 - 0.44 10.7 3.9 0.44 10.7 0.4 2.9 2 0 0 2 2 2 0 PAS fold zf-C2HC_2 PF13913.6 EGF84167.1 - 2.5e-12 46.4 9.0 5.2e-06 26.2 1.7 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EGF84167.1 - 0.0008 19.1 1.7 0.074 12.8 0.1 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type DUF2256 PF10013.9 EGF84167.1 - 0.0056 16.8 1.3 3 8.0 0.2 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2256) V-ATPase_H_N PF03224.14 EGF84167.1 - 0.016 14.5 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 V-ATPase subunit H DHC_N2 PF08393.13 EGF84167.1 - 0.021 14.0 0.4 0.039 13.0 0.4 1.4 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 zf-C2H2_4 PF13894.6 EGF84167.1 - 0.021 15.6 7.0 0.94 10.5 2.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PAS_11 PF14598.6 EGF84167.1 - 0.065 13.4 1.5 0.17 12.0 1.5 1.7 1 0 0 1 1 1 0 PAS domain zf-C2H2 PF00096.26 EGF84167.1 - 0.081 13.4 3.2 5.8 7.6 0.5 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type OrfB_Zn_ribbon PF07282.11 EGF84167.1 - 0.19 11.6 0.8 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-LYAR PF08790.11 EGF84167.1 - 4.1 7.4 7.7 32 4.5 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Aminotran_4 PF01063.19 EGF84168.1 - 1e-18 68.1 0.0 2.5e-18 66.8 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV DUF3770 PF12603.8 EGF84168.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) WD40 PF00400.32 EGF84169.1 - 1.1e-43 146.3 37.1 1.1e-07 32.4 0.1 13.1 14 0 0 14 14 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84169.1 - 2.4e-25 88.6 0.4 0.00016 21.9 0.0 9.1 3 2 6 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGF84169.1 - 1.3e-18 67.3 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EGF84169.1 - 8.6e-09 34.8 2.1 0.29 10.0 0.0 6.3 5 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGF84169.1 - 1.5e-07 31.0 2.9 0.44 9.8 0.0 5.1 4 2 1 5 5 5 3 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 EGF84169.1 - 6.6e-07 29.4 0.6 0.021 14.7 0.2 4.6 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGF84169.1 - 3.7e-06 25.9 0.3 0.0069 15.1 0.0 3.7 2 2 1 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EGF84169.1 - 2.1e-05 24.0 1.5 0.13 11.5 0.0 3.8 3 1 0 4 4 4 2 WD40-like domain PD40 PF07676.12 EGF84169.1 - 0.0004 20.3 4.1 6.9 6.7 0.0 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 EGF84169.1 - 0.0017 17.7 0.0 0.9 8.7 0.0 3.8 4 1 1 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 EGF84169.1 - 0.0092 14.6 0.7 16 3.8 0.0 4.1 4 1 1 5 5 5 0 Cytochrome D1 heme domain Cerato-platanin PF07249.12 EGF84169.1 - 0.089 12.9 0.3 17 5.6 0.1 2.7 2 0 0 2 2 2 0 Cerato-platanin IKI3 PF04762.12 EGF84169.1 - 0.12 10.3 0.0 10 4.0 0.0 2.5 2 1 0 2 2 2 0 IKI3 family Cys_Met_Meta_PP PF01053.20 EGF84170.1 - 2.1e-70 237.2 0.0 5.5e-70 235.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGF84170.1 - 0.057 12.6 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ceramidase PF05875.12 EGF84171.1 - 0.019 14.4 4.7 0.025 14.0 4.7 1.1 1 0 0 1 1 1 0 Ceramidase FYVE PF01363.21 EGF84172.1 - 1.5e-16 60.2 16.6 4.3e-16 58.8 16.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGF84172.1 - 0.34 11.1 11.5 1.3 9.3 11.5 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger zf-RING_5 PF14634.6 EGF84172.1 - 2 8.4 12.2 6.1 6.9 12.2 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Ribosomal_L28 PF00830.19 EGF84173.1 - 5.6e-14 52.1 0.0 9.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Nucleolin_bd PF16725.5 EGF84173.1 - 0.069 12.8 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Nucleolin binding domain vWA-TerF-like PF10138.9 EGF84174.1 - 0.0033 17.6 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGF84174.1 - 0.046 14.0 0.7 0.5 10.6 0.8 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain YjbT PF17089.5 EGF84174.1 - 0.1 12.6 0.0 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family 2-oxoacid_dh PF00198.23 EGF84175.1 - 1e-79 267.3 0.3 1.3e-79 266.9 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGF84175.1 - 2.5e-21 75.3 0.2 5.2e-21 74.3 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Hamartin PF04388.12 EGF84175.1 - 0.00045 19.1 0.2 0.00057 18.7 0.2 1.1 1 0 0 1 1 1 1 Hamartin protein Biotin_lipoyl_2 PF13533.6 EGF84175.1 - 0.0087 15.9 0.0 2.7 7.9 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGF84175.1 - 0.013 16.1 0.0 0.53 11.0 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 EGF84175.1 - 0.014 15.3 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF4813 PF16072.5 EGF84175.1 - 0.024 14.3 23.2 0.043 13.5 23.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) ArfGap PF01412.18 EGF84176.1 - 7.8e-18 64.7 0.1 1.9e-17 63.4 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RHSP PF07999.11 EGF84177.1 - 0.00055 18.9 0.7 0.0028 16.5 0.7 1.8 1 1 0 1 1 1 1 Retrotransposon hot spot protein Beach PF02138.18 EGF84178.1 - 0.0002 20.8 0.9 0.0002 20.8 0.9 1.9 2 0 0 2 2 2 1 Beige/BEACH domain MEIOC PF15189.6 EGF84178.1 - 0.16 11.6 0.3 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC ELYS PF13934.6 EGF84181.1 - 2.1e-44 152.1 0.1 3.5e-44 151.4 0.1 1.4 1 0 0 1 1 1 1 Nuclear pore complex assembly Rsm22 PF09243.10 EGF84182.1 - 6.7e-69 232.2 0.0 9e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_25 PF13649.6 EGF84182.1 - 4e-05 24.2 0.0 0.00014 22.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF84182.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGF84182.1 - 0.0002 22.1 0.0 0.00053 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF84182.1 - 0.00051 19.9 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGF84182.1 - 0.028 15.1 0.0 0.079 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain zinc_ribbon_10 PF10058.9 EGF84183.1 - 4e-15 55.3 0.2 7.3e-15 54.4 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein S1 PF00575.23 EGF84183.1 - 1e-05 25.8 2.0 1.3e-05 25.5 0.8 1.7 1 1 0 1 1 1 1 S1 RNA binding domain Chromate_transp PF02417.15 EGF84183.1 - 0.037 14.2 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromate transporter Borealin PF10512.9 EGF84185.1 - 3.7e-06 26.9 2.1 3.7e-06 26.9 2.1 4.2 3 1 1 4 4 4 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 EGF84185.1 - 0.029 14.0 1.5 0.52 10.0 0.1 2.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Baculo_PEP_C PF04513.12 EGF84185.1 - 0.081 13.0 2.8 6 6.9 0.3 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YscJ_FliF_C PF08345.11 EGF84185.1 - 0.16 12.3 6.9 0.81 10.0 6.8 2.3 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal HSCB_C PF07743.13 EGF84185.1 - 0.96 10.0 9.3 0.74 10.3 0.6 3.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF148 PF02520.17 EGF84185.1 - 1.4 9.1 6.9 0.42 10.7 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF148 V-SNARE PF05008.15 EGF84185.1 - 9.5 6.7 9.6 5.2 7.5 0.3 3.6 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus WD40 PF00400.32 EGF84187.1 - 6.3e-21 74.3 17.2 5.9e-05 23.8 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84187.1 - 8.2e-14 51.7 4.8 0.00013 22.2 0.2 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGF84187.1 - 7.4e-08 32.5 0.1 0.034 14.0 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGF84187.1 - 8.8e-05 21.6 0.2 0.035 13.1 0.1 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGF84187.1 - 0.012 15.0 0.0 0.57 9.5 0.0 2.7 2 1 0 3 3 3 0 WD40-like domain Staphostatin_B PF09023.10 EGF84187.1 - 0.072 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Staphostatin B HPS3_N PF14761.6 EGF84187.1 - 0.13 11.7 0.0 13 5.2 0.0 2.5 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Peptidase_M24 PF00557.24 EGF84188.1 - 9.3e-54 182.3 0.0 1.1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 HSP70 PF00012.20 EGF84189.1 - 0.0013 17.0 0.4 0.0015 16.8 0.4 1.2 1 0 0 1 1 1 1 Hsp70 protein ATP-synt_D PF01813.17 EGF84189.1 - 0.0078 16.1 0.0 0.053 13.3 0.0 2.0 1 1 0 1 1 1 1 ATP synthase subunit D DUF4692 PF15763.5 EGF84189.1 - 9.4 6.7 10.0 15 6.0 10.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CHORD PF04968.12 EGF84190.1 - 4.2e-53 177.9 16.9 2.8e-26 92.0 3.4 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 EGF84190.1 - 7.2e-16 59.0 0.5 1.3e-15 58.2 0.5 1.4 1 0 0 1 1 1 1 CS domain CxC6 PF18721.1 EGF84190.1 - 0.44 10.8 4.2 3.6 7.9 0.0 3.1 3 0 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases BTK PF00779.19 EGF84190.1 - 0.81 9.6 8.1 8.6 6.3 0.9 3.5 3 0 0 3 3 3 0 BTK motif Metallophos PF00149.28 EGF84191.1 - 3.7e-40 138.6 0.1 4.7e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGF84191.1 - 1.4e-23 83.1 1.0 2.2e-23 82.4 0.4 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PHM7_ext PF12621.8 EGF84195.1 - 0.062 13.5 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Homeodomain PF00046.29 EGF84195.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Homeodomain AAA_5 PF07728.14 EGF84196.1 - 4.6e-71 237.2 0.0 1.2e-25 90.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF84196.1 - 5.5e-10 39.9 0.2 0.011 16.1 0.0 4.8 4 0 0 4 4 4 2 AAA ATPase domain ABC_tran PF00005.27 EGF84196.1 - 4.6e-05 23.9 0.0 0.043 14.3 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 EGF84196.1 - 0.00016 21.3 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 EGF84196.1 - 0.00064 19.4 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGF84196.1 - 0.0031 17.8 0.2 6 7.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 EGF84196.1 - 0.0038 17.3 0.0 2.5 8.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGF84196.1 - 0.0063 16.9 0.0 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGF84196.1 - 0.0077 16.8 0.0 0.068 13.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 EGF84196.1 - 0.0083 16.0 0.0 1.4 8.7 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EGF84196.1 - 0.0083 16.3 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EGF84196.1 - 0.009 15.2 0.0 0.34 10.0 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Rad17 PF03215.15 EGF84196.1 - 0.017 15.1 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 EGF84196.1 - 0.017 14.8 0.0 3.8 7.2 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGF84196.1 - 0.017 15.0 0.0 0.095 12.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EGF84196.1 - 0.023 14.6 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EGF84196.1 - 0.024 14.6 0.2 1.3 8.9 0.0 3.4 4 1 0 4 4 3 0 NACHT domain TsaE PF02367.17 EGF84196.1 - 0.035 14.1 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EGF84196.1 - 0.064 13.7 2.1 0.078 13.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 EGF84196.1 - 0.072 12.2 0.0 3.7 6.6 0.0 2.5 2 0 0 2 2 2 0 MCM P-loop domain ATP-synt_ab PF00006.25 EGF84196.1 - 0.082 12.5 0.1 4.2 7.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EGF84196.1 - 0.095 13.1 0.0 0.63 10.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EGF84196.1 - 0.11 11.7 0.0 0.51 9.6 0.0 2.0 3 0 0 3 3 3 0 Zeta toxin TniB PF05621.11 EGF84196.1 - 0.11 11.9 0.0 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 EGF84196.1 - 0.14 11.5 0.0 7.3 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family polyprenyl_synt PF00348.17 EGF84198.1 - 2.7e-71 239.6 0.0 3.3e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF5601 PF18151.1 EGF84199.1 - 0.00025 21.3 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Lyase_1 PF00206.20 EGF84200.1 - 4.5e-96 321.9 0.0 1.2e-95 320.5 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 EGF84200.1 - 9.2e-18 64.8 0.3 2e-17 63.7 0.3 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Pkinase PF00069.25 EGF84201.1 - 7.8e-24 84.4 0.0 1.4e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84201.1 - 2e-09 37.1 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGF84201.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGF84201.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGF84202.1 - 1.5e-06 27.8 0.1 1.9e-06 27.5 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84202.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Vps51 PF08700.11 EGF84203.1 - 0.025 14.6 0.0 0.1 12.7 0.0 2.1 1 0 0 1 1 1 0 Vps51/Vps67 CBFD_NFYB_HMF PF00808.23 EGF84205.1 - 4.6e-18 65.3 0.1 9.8e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGF84205.1 - 0.0002 21.3 0.1 0.0019 18.1 0.0 2.0 1 1 1 2 2 2 1 Bromodomain associated CENP-T_C PF15511.6 EGF84205.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EGF84205.1 - 0.028 14.4 0.5 0.31 11.1 0.1 2.2 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit Ras PF00071.22 EGF84207.1 - 2.1e-40 137.9 0.1 2.4e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF84207.1 - 2.7e-24 85.7 0.1 5.2e-24 84.8 0.0 1.4 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF84207.1 - 2.8e-12 46.5 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGF84207.1 - 9.9e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGF84207.1 - 0.0002 20.8 0.0 0.00029 20.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGF84207.1 - 0.0038 17.0 0.0 2.3 8.0 0.0 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGF84207.1 - 0.019 14.9 0.1 0.29 11.0 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGF84207.1 - 0.052 13.3 0.1 0.15 11.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain RPEL PF02755.15 EGF84208.1 - 6.7e-13 47.9 15.0 0.00012 21.7 0.0 4.5 4 0 0 4 4 4 4 RPEL repeat CDC24_OB1 PF17246.2 EGF84208.1 - 0.0083 16.2 0.9 0.019 15.1 0.8 1.8 1 1 0 1 1 1 1 Cell division control protein 24, OB domain 1 SET PF00856.28 EGF84209.1 - 1.1e-09 38.9 1.8 7.4e-09 36.2 1.8 1.9 1 1 0 1 1 1 1 SET domain WD40 PF00400.32 EGF84211.1 - 1.6e-06 28.8 2.7 0.0017 19.1 0.0 4.8 5 1 1 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 EGF84211.1 - 0.001 19.0 0.0 2.7 7.8 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGF84211.1 - 0.031 14.6 0.0 5.3 7.4 0.0 3.9 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EGF84212.1 - 1.7e-67 227.6 0.0 2.2e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84212.1 - 8e-37 126.9 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HMG_box PF00505.19 EGF84214.1 - 6.9e-16 58.4 1.6 8.5e-16 58.1 1.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGF84214.1 - 1.6e-07 31.8 0.8 1.7e-07 31.7 0.8 1.0 1 0 0 1 1 1 1 HMG-box domain PGDYG PF14083.6 EGF84214.1 - 0.031 14.5 0.1 0.038 14.2 0.1 1.2 1 1 0 1 1 1 0 PGDYG protein DUF3188 PF11384.8 EGF84215.1 - 0.2 11.4 0.2 8.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Vasohibin PF14822.6 EGF84216.1 - 1.7e-36 125.7 2.5 2.7e-25 89.0 0.1 3.0 1 1 2 3 3 3 3 Vasohibin Utp13 PF08625.11 EGF84217.1 - 0.3 11.0 2.9 0.98 9.3 2.9 2.1 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain AAA_23 PF13476.6 EGF84217.1 - 8 6.9 15.9 3e+02 1.8 15.9 2.4 1 1 0 1 1 1 0 AAA domain Peptidase_M16_C PF05193.21 EGF84218.1 - 2.5e-20 73.2 0.0 4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGF84218.1 - 7.1e-16 58.5 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) MFS_1 PF07690.16 EGF84219.1 - 3e-18 65.9 25.8 2.5e-11 43.1 15.7 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EGF84219.1 - 0.038 13.8 0.3 0.038 13.8 0.3 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Chromo PF00385.24 EGF84219.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 EGF84220.1 - 9e-66 221.9 0.0 1.2e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84220.1 - 1.2e-48 165.6 0.0 1.6e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF84220.1 - 1.5e-06 27.7 0.0 0.00067 19.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGF84220.1 - 0.00028 19.8 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGF84220.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGF84220.1 - 0.04 13.8 0.0 0.096 12.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF84220.1 - 0.11 11.5 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain AAA PF00004.29 EGF84221.1 - 1.7e-37 128.8 0.1 1.7e-36 125.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF84221.1 - 4.4e-13 48.8 0.1 1.6e-12 47.0 0.1 2.0 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EGF84221.1 - 4.8e-10 39.3 0.1 1.8e-09 37.4 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EGF84221.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGF84221.1 - 0.00065 20.0 0.3 0.0073 16.6 0.3 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGF84221.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EGF84221.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGF84221.1 - 0.0029 17.6 0.1 0.0092 16.0 0.1 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGF84221.1 - 0.0032 17.6 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGF84221.1 - 0.0041 16.5 0.1 0.012 15.0 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGF84221.1 - 0.0045 17.2 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGF84221.1 - 0.0057 17.2 0.2 0.037 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGF84221.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGF84221.1 - 0.0078 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGF84221.1 - 0.0099 15.2 0.1 0.45 9.8 0.1 2.5 1 1 1 2 2 2 1 KaiC MHCassoc_trimer PF08831.10 EGF84221.1 - 0.012 15.6 0.1 0.08 13.0 0.0 2.2 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain AAA_28 PF13521.6 EGF84221.1 - 0.017 15.4 0.1 0.063 13.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGF84221.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGF84221.1 - 0.041 13.3 0.2 0.089 12.2 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein STIL_N PF15253.6 EGF84221.1 - 0.052 12.5 0.1 0.089 11.7 0.1 1.3 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus AAA_7 PF12775.7 EGF84221.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EGF84221.1 - 0.092 12.0 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 EGF84221.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EGF84221.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 EGF84221.1 - 0.13 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EGF84221.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGF84221.1 - 0.17 11.8 0.1 0.87 9.5 0.1 2.2 2 1 1 3 3 3 0 NACHT domain Arf PF00025.21 EGF84222.1 - 3e-70 235.2 1.3 3.4e-70 235.1 1.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGF84222.1 - 2.6e-13 50.2 0.0 4.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGF84222.1 - 4.4e-13 49.1 0.0 5.9e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGF84222.1 - 1.6e-12 47.2 2.3 4.8e-08 32.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGF84222.1 - 1.2e-11 44.5 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGF84222.1 - 1.1e-09 38.1 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGF84222.1 - 1.1e-08 35.2 0.0 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGF84222.1 - 4.8e-05 23.0 0.0 0.00038 20.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF1073 PF06381.11 EGF84222.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) cobW PF02492.19 EGF84222.1 - 0.015 14.9 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGF84222.1 - 0.018 15.0 0.4 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.18 EGF84222.1 - 0.028 13.9 0.1 0.061 12.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EGF84222.1 - 0.035 14.4 0.2 0.14 12.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGF84222.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SHIPPO-rpt PF07004.12 EGF84223.1 - 1.8e-07 31.7 58.6 0.59 11.1 1.5 11.5 11 0 0 11 11 11 7 Sperm-tail PG-rich repeat Fimbrial_PilY2 PF14481.6 EGF84223.1 - 0.088 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DPM3 PF08285.11 EGF84224.1 - 3.6e-28 97.6 0.2 4e-28 97.4 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Arrestin_C PF02752.22 EGF84225.1 - 4.1e-06 27.3 0.3 0.00019 21.9 0.1 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGF84225.1 - 0.0045 17.0 0.0 0.049 13.7 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SPX PF03105.19 EGF84226.1 - 2.1e-37 130.0 0.0 2.7e-22 80.2 0.0 2.2 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 EGF84226.1 - 6.4e-28 97.8 56.6 4.3e-26 91.8 27.8 2.6 1 1 2 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.19 EGF84226.1 - 1.4e-27 96.9 31.5 1.9e-27 96.4 31.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region Thioredoxin_16 PF18569.1 EGF84227.1 - 0.053 13.6 2.5 0.15 12.2 2.5 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain T2SSG PF08334.11 EGF84227.1 - 0.07 13.2 3.6 0.18 11.9 3.6 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Proteasome PF00227.26 EGF84228.1 - 2.3e-48 164.2 0.3 2.7e-48 164.0 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 EGF84229.1 - 3e-11 43.7 8.5 0.00045 21.0 0.7 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84229.1 - 0.0004 20.6 1.4 0.58 10.5 0.1 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S13_N PF08069.12 EGF84230.1 - 6.2e-32 109.4 0.1 1.2e-31 108.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGF84230.1 - 8.6e-13 48.3 0.1 1.3e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EGF84230.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.6 1 1 0 1 1 1 0 'Paired box' domain Rad21_Rec8_N PF04825.13 EGF84231.1 - 7.8e-26 90.4 0.0 2e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGF84231.1 - 5.2e-08 32.0 0.0 1.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DEAD PF00270.29 EGF84232.1 - 1.4e-46 158.4 0.0 3.1e-46 157.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase GUCT PF08152.12 EGF84232.1 - 7e-29 100.0 0.0 2.9e-28 98.0 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain Helicase_C PF00271.31 EGF84232.1 - 4.3e-27 94.7 0.0 2.5e-26 92.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF84232.1 - 2e-07 31.2 1.4 3.4e-06 27.2 0.0 2.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGF84232.1 - 0.004 16.5 0.0 0.004 16.5 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit VWA_3 PF13768.6 EGF84232.1 - 0.15 11.9 0.5 1.8 8.5 0.1 2.6 3 0 0 3 3 3 0 von Willebrand factor type A domain Pneumo_att_G PF05539.11 EGF84232.1 - 0.45 10.1 4.8 0.68 9.5 4.8 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Zip PF02535.22 EGF84232.1 - 0.75 9.0 3.8 1.4 8.0 3.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Esterase PF00756.20 EGF84233.1 - 5.1e-05 23.0 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGF84233.1 - 0.00054 19.5 0.0 0.0019 17.7 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Tannase PF07519.11 EGF84233.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EGF84233.1 - 0.053 12.8 0.1 0.48 9.7 0.1 2.0 1 1 0 2 2 2 0 Serine aminopeptidase, S33 ELO PF01151.18 EGF84234.1 - 1e-54 185.7 24.9 1.2e-54 185.5 24.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.7 EGF84235.1 - 7.3e-11 41.8 0.1 2.1e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGF84235.1 - 3.8e-07 29.8 0.1 8.9e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EGF84235.1 - 1.4e-06 28.9 10.0 0.0092 16.8 0.1 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84235.1 - 2e-05 24.8 0.4 0.27 11.5 0.1 3.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EGF84235.1 - 0.011 15.6 0.0 0.42 10.6 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Mito_carr PF00153.27 EGF84236.1 - 1.5e-67 223.5 1.1 1.7e-21 75.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 EGF84237.1 - 1.6e-11 44.6 0.1 3.8e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 PCI domain DUF4451 PF14616.6 EGF84239.1 - 3.3e-19 69.3 1.9 1.8e-18 66.9 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) DUF4616 PF15394.6 EGF84239.1 - 0.31 9.9 3.3 0.32 9.9 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4616) Opiods_neuropep PF01160.18 EGF84242.1 - 0.023 14.8 0.2 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide LIM PF00412.22 EGF84243.1 - 3.3e-25 88.1 22.4 8.7e-13 48.3 8.3 2.2 2 0 0 2 2 2 2 LIM domain Cytochrome_CBB3 PF13442.6 EGF84243.1 - 0.047 14.0 8.2 0.7 10.2 0.0 4.0 4 0 0 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III Zn-ribbon_8 PF09723.10 EGF84243.1 - 0.087 13.0 0.9 0.087 13.0 0.9 3.4 4 0 0 4 4 4 0 Zinc ribbon domain RecQ_Zn_bind PF16124.5 EGF84243.1 - 0.15 12.8 11.0 0.29 11.9 0.3 2.7 3 0 0 3 3 3 0 RecQ zinc-binding Yippee-Mis18 PF03226.14 EGF84243.1 - 8 6.7 17.6 4.2 7.6 5.2 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nop10p PF04135.12 EGF84244.1 - 3.2e-23 81.5 0.7 3.7e-23 81.3 0.7 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Helicase_C PF00271.31 EGF84245.1 - 1.3e-21 77.0 0.1 1.5e-20 73.5 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGF84245.1 - 2.1e-21 76.6 0.0 4.8e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGF84245.1 - 5.2e-16 58.9 0.0 1.8e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGF84245.1 - 0.0015 18.3 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGF84245.1 - 0.012 15.9 0.0 0.05 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Nod1 PF17114.5 EGF84245.1 - 0.12 12.6 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 TPR_19 PF14559.6 EGF84246.1 - 0.00026 21.5 0.0 0.2 12.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 EGF84246.1 - 0.0011 19.0 0.1 1 9.8 0.0 4.6 5 0 0 5 5 5 1 PPR repeat TPR_14 PF13428.6 EGF84246.1 - 0.019 15.8 0.1 24 6.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 EGF84246.1 - 0.07 12.8 0.7 13 5.6 0.0 2.9 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_12 PF13424.6 EGF84246.1 - 0.14 12.4 0.1 5.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4460 PF14687.6 EGF84246.1 - 1.5 8.9 4.4 21 5.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) FH2 PF02181.23 EGF84247.1 - 6.6e-85 285.4 5.2 6.6e-85 285.4 5.2 3.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGF84247.1 - 1.3e-11 44.5 23.4 0.0057 16.2 0.3 7.2 7 0 0 7 7 7 6 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGF84247.1 - 1.4e-09 37.9 0.1 5.7e-09 35.9 0.1 2.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF4140 PF13600.6 EGF84247.1 - 0.089 13.2 2.9 26 5.3 0.2 4.3 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF667 PF05018.13 EGF84248.1 - 3.3e-18 66.1 0.0 9.6e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF667) GDP_Man_Dehyd PF16363.5 EGF84249.1 - 2.5e-72 244.1 0.0 2.9e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGF84249.1 - 8.2e-56 189.2 0.0 1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGF84249.1 - 1.2e-26 93.4 0.0 1.7e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGF84249.1 - 1.1e-19 70.6 0.0 2.6e-18 66.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGF84249.1 - 9.3e-19 67.7 0.0 5.4e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGF84249.1 - 1.3e-13 50.7 0.0 2.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGF84249.1 - 1.8e-06 28.0 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EGF84249.1 - 0.11 11.9 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase CDH-cyt PF16010.5 EGF84250.1 - 1.2e-08 34.9 0.2 3.7e-08 33.3 0.2 1.7 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EGF84250.1 - 0.00017 21.7 9.5 0.00032 20.8 9.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EGF84250.1 - 0.0017 18.6 0.1 0.003 17.8 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 EGF84250.1 - 0.16 11.8 10.7 0.79 9.5 10.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EGF84250.1 - 0.22 11.6 8.8 0.16 12.1 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) AAA_lid_2 PF17863.1 EGF84251.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain CybS PF05328.12 EGF84252.1 - 1.8e-32 111.8 0.8 2e-32 111.7 0.8 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit THEG4 PF15834.5 EGF84253.1 - 4.3 7.3 8.5 1.5 8.8 2.3 3.3 2 0 0 2 2 2 0 Testis highly expressed protein 4 F-box-like PF12937.7 EGF84254.1 - 0.00015 21.6 0.1 0.0003 20.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGF84254.1 - 0.00017 21.4 1.7 0.15 12.2 0.2 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 EGF84254.1 - 0.00069 20.0 0.6 0.002 18.5 0.1 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF84254.1 - 0.034 13.9 0.2 0.56 10.0 0.2 2.4 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 EGF84254.1 - 0.16 12.6 0.3 33 5.6 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat DMRL_synthase PF00885.19 EGF84255.1 - 2e-53 180.0 0.0 2.2e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase GCP_C_terminal PF04130.13 EGF84256.1 - 5.1e-74 249.5 0.7 8e-74 248.9 0.7 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGF84256.1 - 1.3e-59 202.3 0.1 2.4e-59 201.5 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal PTPA PF03095.15 EGF84257.1 - 1.2e-125 419.0 0.0 1.4e-125 418.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein P34-Arc PF04045.14 EGF84258.1 - 7.8e-103 343.3 0.0 9.3e-103 343.1 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc FAD_binding_1 PF00667.20 EGF84259.1 - 7.1e-49 166.4 0.1 2.5e-48 164.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 EGF84259.1 - 9.7e-28 97.2 0.5 2.4e-27 95.9 0.5 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGF84259.1 - 1.8e-13 51.1 0.0 3.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Sod_Fe_C PF02777.18 EGF84260.1 - 2.6e-31 107.8 0.5 2.9e-31 107.7 0.5 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_C PF02777.18 EGF84261.1 - 1.7e-25 89.2 0.1 3e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Cas_St_Csn2 PF16813.5 EGF84261.1 - 0.016 14.3 0.3 0.021 13.9 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St Pkinase PF00069.25 EGF84264.1 - 1e-22 80.8 0.0 1.6e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84264.1 - 6e-10 38.8 0.0 9.6e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF84264.1 - 2.3e-05 23.4 0.0 4.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase tRNA-synt_2b PF00587.25 EGF84265.1 - 2.8e-38 131.7 0.0 6.7e-38 130.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGF84265.1 - 3e-16 59.3 0.0 5.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGF84265.1 - 2.7e-09 37.0 0.0 5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_12 PF13424.6 EGF84266.1 - 9.6e-19 67.5 0.9 5.4e-05 23.4 0.1 4.4 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGF84266.1 - 1.4e-12 46.8 3.2 0.083 13.2 0.3 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGF84266.1 - 1.5e-12 46.7 4.1 0.08 12.8 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGF84266.1 - 6.5e-12 44.6 4.9 0.062 13.4 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGF84266.1 - 2.1e-09 36.9 0.4 0.081 12.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGF84266.1 - 0.00037 21.0 4.4 0.74 10.4 0.2 3.9 4 2 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGF84266.1 - 0.0015 18.8 0.2 15 6.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGF84266.1 - 0.0019 17.6 3.3 0.038 13.4 0.3 2.6 2 1 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EGF84266.1 - 0.0039 17.9 4.7 17 6.5 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGF84266.1 - 0.0041 17.1 1.9 7.9 6.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGF84266.1 - 0.0094 16.5 7.4 3.6 8.4 0.2 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF84266.1 - 0.026 14.7 4.2 21 5.4 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGF84266.1 - 0.15 11.8 7.6 0.28 10.9 0.2 4.3 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 EGF84266.1 - 0.37 11.5 6.5 41 4.9 1.3 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGF84266.1 - 0.47 10.5 11.1 16 5.7 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF726 PF05277.12 EGF84267.1 - 3.9e-70 236.5 1.3 6.5e-63 212.7 0.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF726) FSH1 PF03959.13 EGF84267.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) zf-DNL PF05180.12 EGF84268.1 - 1.3e-29 101.9 0.5 3.3e-29 100.6 0.5 1.7 1 0 0 1 1 1 1 DNL zinc finger Sod_Fe_C PF02777.18 EGF84269.1 - 4.1e-28 97.5 1.1 4.6e-28 97.4 1.1 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain MA3 PF02847.17 EGF84270.1 - 0.024 14.6 1.6 0.53 10.3 0.1 2.4 1 1 1 2 2 2 0 MA3 domain IL32 PF15225.6 EGF84270.1 - 0.027 14.8 0.0 0.17 12.2 0.0 2.2 1 1 0 2 2 2 0 Interleukin 32 RIH_assoc PF08454.11 EGF84270.1 - 0.065 13.1 0.6 0.53 10.2 0.6 2.3 1 1 0 1 1 1 0 RyR and IP3R Homology associated Sod_Fe_C PF02777.18 EGF84271.1 - 1.7e-33 114.8 0.4 3.4e-33 113.9 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGF84271.1 - 2.9e-23 82.1 1.9 2e-22 79.5 1.9 2.2 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain 2OG-FeII_Oxy_2 PF13532.6 EGF84272.1 - 4.4e-10 40.1 0.0 5e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glycoprot_B_PH2 PF17417.2 EGF84272.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain Pecanex_C PF05041.15 EGF84273.1 - 3.5e-21 75.8 0.0 6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Cation_efflux PF01545.21 EGF84274.1 - 1.1e-22 80.8 14.5 1.4e-22 80.4 14.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGF84274.1 - 2.2e-11 43.7 0.1 3.8e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Helicase_PWI PF18149.1 EGF84275.1 - 0.028 14.6 2.5 0.043 14.0 2.5 1.3 1 0 0 1 1 1 0 N-terminal helicase PWI domain Hrs_helical PF12210.8 EGF84275.1 - 0.25 11.9 7.8 0.067 13.7 3.7 2.1 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4246 PF14033.6 EGF84276.1 - 2.8e-95 320.1 0.0 4.5e-95 319.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arm PF00514.23 EGF84276.1 - 0.0034 17.4 0.2 0.037 14.1 0.0 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EGF84276.1 - 0.0044 15.6 0.1 0.0044 15.6 0.1 2.2 2 1 1 3 3 3 1 Adaptin N terminal region Mac PF12464.8 EGF84277.1 - 0.064 13.5 1.1 0.19 12.0 1.1 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase Peptidase_S41 PF03572.18 EGF84278.1 - 2e-13 50.2 0.0 4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 MxiM PF11441.8 EGF84278.1 - 0.011 16.1 0.2 0.027 14.7 0.2 1.6 1 0 0 1 1 1 0 Pilot protein MxiM PPR_1 PF12854.7 EGF84278.1 - 0.24 11.1 0.4 0.43 10.3 0.4 1.4 1 0 0 1 1 1 0 PPR repeat DUF4246 PF14033.6 EGF84279.1 - 4.1e-69 233.9 3.5 7.4e-53 180.3 0.0 3.6 2 1 2 4 4 4 3 Protein of unknown function (DUF4246) Adaptin_N PF01602.20 EGF84279.1 - 0.0016 17.1 3.5 0.0024 16.5 0.1 2.5 2 1 1 3 3 3 1 Adaptin N terminal region Arm PF00514.23 EGF84279.1 - 0.0027 17.7 0.2 0.034 14.2 0.0 2.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Creatinase_N_2 PF16189.5 EGF84280.1 - 4.1e-49 166.8 0.1 2.5e-47 161.0 0.0 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGF84280.1 - 4.7e-44 150.6 0.0 8.4e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGF84280.1 - 4.6e-26 92.0 0.3 8.7e-19 68.5 0.0 3.1 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGF84280.1 - 3.6e-23 81.4 0.0 1e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 HPTransfase PF10090.9 EGF84280.1 - 0.027 14.3 0.0 0.073 12.9 0.0 1.7 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain PIG-S PF10510.9 EGF84282.1 - 6.5e-115 384.9 11.5 4.8e-104 349.0 1.8 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Fringe PF02434.16 EGF84283.1 - 9.3e-10 38.4 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EGF84283.1 - 8.2e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_4 PF14295.6 EGF84283.1 - 2.5e-08 33.7 1.4 6.1e-08 32.5 1.4 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EGF84283.1 - 4.2e-06 26.6 0.1 8e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 EGF84283.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase PAN_2 PF08276.11 EGF84283.1 - 0.032 14.3 0.6 0.072 13.2 0.6 1.5 1 0 0 1 1 1 0 PAN-like domain Glyco_transf_34 PF05637.12 EGF84283.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family PAN_3 PF08277.12 EGF84283.1 - 0.085 12.7 4.6 0.047 13.5 2.0 1.8 2 0 0 2 2 2 0 PAN-like domain SF1-HH PF16275.5 EGF84284.1 - 2.4e-36 124.5 0.1 4e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EGF84284.1 - 7.3e-10 38.5 0.9 1.5e-09 37.5 0.9 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EGF84284.1 - 5.4e-08 32.6 6.6 0.00017 21.5 2.7 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EGF84284.1 - 0.0052 16.6 7.2 0.014 15.3 0.6 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGF84284.1 - 0.02 14.8 1.9 0.02 14.8 1.9 2.0 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGF84284.1 - 0.049 13.4 7.1 0.049 13.4 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 EGF84284.1 - 0.065 13.5 1.8 0.16 12.3 1.8 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-CCHC_2 PF13696.6 EGF84284.1 - 0.27 11.1 9.2 0.48 10.3 1.4 2.5 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 EGF84284.1 - 0.3 11.5 5.6 0.71 10.3 5.6 1.6 1 0 0 1 1 1 0 DnaJ central domain KH_2 PF07650.17 EGF84284.1 - 4.7 7.1 7.8 0.54 10.1 0.8 2.5 3 0 0 3 3 3 0 KH domain Enkurin PF13864.6 EGF84285.1 - 1.2e-21 77.0 0.4 1.2e-21 77.0 0.4 1.8 2 0 0 2 2 2 1 Calmodulin-binding YtxH PF12732.7 EGF84285.1 - 0.069 13.7 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 YtxH-like protein DUF908 PF06012.12 EGF84285.1 - 0.1 12.0 2.2 0.13 11.7 2.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Pribosyltran_N PF13793.6 EGF84286.1 - 5.2e-43 145.7 0.4 1.3e-41 141.2 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGF84286.1 - 1.1e-39 136.3 1.6 2.3e-33 115.8 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGF84286.1 - 6.5e-14 51.7 0.1 1.3e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DnaJ PF00226.31 EGF84287.1 - 2.3e-19 69.3 0.8 8.4e-19 67.5 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 EGF84287.1 - 4.5e-10 39.6 0.6 0.00091 19.4 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain RAC_head PF16717.5 EGF84287.1 - 3.1e-08 34.5 0.9 3.1e-08 34.5 0.9 3.9 3 1 1 4 4 4 1 Ribosome-associated complex head domain Myb_DNA-bind_6 PF13921.6 EGF84287.1 - 0.0073 16.5 3.1 0.44 10.8 0.0 3.5 4 0 0 4 4 4 1 Myb-like DNA-binding domain Atg29_N PF18388.1 EGF84287.1 - 0.014 15.2 4.5 0.51 10.2 0.1 3.5 3 0 0 3 3 3 0 Atg29 N-terminal domain PAXX PF15384.6 EGF84288.1 - 0.0043 16.8 0.1 0.0044 16.7 0.1 1.1 1 0 0 1 1 1 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 SRP9-21 PF05486.12 EGF84288.1 - 0.029 14.7 0.1 0.029 14.7 0.1 2.3 2 1 1 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) Ank_2 PF12796.7 EGF84289.1 - 6.9e-18 65.0 0.2 1.2e-08 35.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGF84289.1 - 2.2e-16 59.7 0.4 1e-06 28.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGF84289.1 - 2e-14 53.3 0.1 3.6e-06 27.2 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EGF84289.1 - 2.8e-13 50.1 1.0 3.2e-08 33.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGF84289.1 - 3.6e-12 45.3 0.1 0.0066 16.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat LSM PF01423.22 EGF84290.1 - 1.1e-16 60.3 0.0 1.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGF84290.1 - 0.0048 17.0 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain RhlB PF12300.8 EGF84290.1 - 0.034 14.3 4.2 0.04 14.0 4.2 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Swi5 PF07061.11 EGF84292.1 - 2.4e-10 40.3 0.7 6e-10 39.1 0.4 1.7 2 0 0 2 2 2 1 Swi5 DUF4588 PF15251.6 EGF84293.1 - 0.00088 19.1 5.5 0.0034 17.2 5.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.13 EGF84293.1 - 0.03 14.5 0.5 0.13 12.5 0.3 2.1 2 0 0 2 2 2 0 Hairy Orange RasGEF PF00617.19 EGF84294.1 - 2.9e-13 50.4 0.0 4.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain Il2rg PF15874.5 EGF84295.1 - 2e-26 92.1 0.0 3e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain Kelch_3 PF13415.6 EGF84296.1 - 2e-26 91.7 9.6 7.2e-06 26.1 0.0 8.1 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGF84296.1 - 1.6e-25 88.6 3.2 0.003 17.5 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EGF84296.1 - 1.7e-24 85.1 0.9 0.00067 19.2 0.0 7.1 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGF84296.1 - 1e-21 76.7 4.4 0.0025 17.8 0.0 7.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGF84296.1 - 1.8e-19 68.9 2.5 0.079 13.0 0.0 7.6 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGF84296.1 - 1.8e-18 66.1 2.9 0.029 14.7 0.0 7.6 7 0 0 7 7 7 4 Kelch motif JHY PF15261.6 EGF84297.1 - 1 10.1 4.4 0.43 11.3 0.4 2.3 2 0 0 2 2 2 0 Jhy protein Metallophos PF00149.28 EGF84298.1 - 8.9e-36 124.3 0.0 1.6e-35 123.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EGF84298.1 - 0.007 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) Pyr_redox_2 PF07992.14 EGF84300.1 - 2e-48 165.1 0.3 2.3e-48 164.9 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGF84300.1 - 1.5e-15 57.5 0.5 9.2e-13 48.6 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGF84300.1 - 1.6e-13 50.6 0.1 2.1e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGF84300.1 - 1.1e-05 24.8 1.2 0.00018 20.8 0.1 2.7 2 1 0 3 3 3 1 Thi4 family GIDA PF01134.22 EGF84300.1 - 0.00049 19.3 4.5 0.0069 15.5 0.3 3.5 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGF84300.1 - 0.0013 17.9 2.2 0.011 14.9 0.6 3.0 2 1 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EGF84300.1 - 0.0018 17.7 0.2 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGF84300.1 - 0.0021 18.3 0.8 0.029 14.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGF84300.1 - 0.0049 16.2 0.4 0.056 12.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGF84300.1 - 0.0053 16.4 3.0 0.23 11.0 0.8 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGF84300.1 - 0.0064 16.9 0.3 0.25 11.8 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 EGF84300.1 - 0.0081 14.9 1.5 0.13 11.0 0.9 2.5 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 EGF84300.1 - 0.013 14.7 0.2 0.46 9.6 0.1 2.7 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EGF84300.1 - 0.046 12.6 1.6 0.19 10.5 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 EGF84300.1 - 0.054 13.5 0.1 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mtr2 PF10429.9 EGF84300.1 - 0.1 12.5 0.0 1.4 8.9 0.0 2.1 1 1 1 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 Peptidase_S24 PF00717.23 EGF84301.1 - 2.6e-10 40.1 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Ribosomal_S8 PF00410.19 EGF84302.1 - 2.2e-22 79.4 0.0 3e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-DNL PF05180.12 EGF84303.1 - 1.2e-30 105.2 0.5 1.4e-30 105.1 0.5 1.0 1 0 0 1 1 1 1 DNL zinc finger ZZ PF00569.17 EGF84303.1 - 0.045 13.6 2.5 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type TFIIS_C PF01096.18 EGF84303.1 - 0.11 12.3 2.3 3.4 7.6 0.3 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Sod_Fe_C PF02777.18 EGF84304.1 - 3e-31 107.6 0.5 3.4e-31 107.5 0.5 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_C PF02777.18 EGF84305.1 - 2.1e-32 111.3 0.4 2.6e-32 111.0 0.4 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain HLH PF00010.26 EGF84307.1 - 4.1e-11 42.7 0.2 6.9e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Polysacc_deac_1 PF01522.21 EGF84309.1 - 1.5e-29 102.4 0.0 2.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase RRP36 PF06102.12 EGF84310.1 - 3.7e-47 160.4 19.6 4.5e-47 160.1 19.6 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 DUF573 PF04504.14 EGF84310.1 - 0.66 10.7 12.3 0.15 12.8 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DUF2259 PF10016.9 EGF84310.1 - 0.92 9.4 3.7 1.2 9.0 3.7 1.2 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) DUF1192 PF06698.11 EGF84310.1 - 1.3 9.1 6.0 1.7 8.8 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) HMGL-like PF00682.19 EGF84311.1 - 1e-61 208.8 0.2 1.2e-61 208.6 0.2 1.0 1 0 0 1 1 1 1 HMGL-like RGCC PF15151.6 EGF84312.1 - 0.012 15.8 2.4 0.085 13.1 2.4 2.5 1 0 0 1 1 1 0 Response gene to complement 32 protein family PHTB1_N PF14727.6 EGF84313.1 - 0.0038 16.6 0.4 0.027 13.8 0.0 2.2 2 1 0 2 2 2 1 PTHB1 N-terminus WD40_like PF17005.5 EGF84313.1 - 0.033 13.5 0.1 0.26 10.6 0.1 2.0 1 1 0 2 2 2 0 WD40-like domain RNase_T PF00929.24 EGF84314.1 - 2.6e-34 119.2 0.1 2.9e-34 119.0 0.1 1.0 1 0 0 1 1 1 1 Exonuclease zf-H2C2_2 PF13465.6 EGF84315.1 - 4.7e-27 93.2 35.7 2.6e-07 30.7 2.9 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 EGF84315.1 - 1.7e-18 66.0 44.7 7.5e-05 23.0 1.5 8.4 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGF84315.1 - 3.7e-08 33.5 47.6 0.14 13.0 1.9 8.8 9 0 0 9 9 9 5 C2H2-type zinc finger FOXP-CC PF16159.5 EGF84315.1 - 3.2e-06 27.7 26.1 0.18 12.4 0.2 6.0 5 1 1 6 6 6 4 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EGF84315.1 - 5.2e-05 23.5 22.1 0.049 13.9 3.0 5.5 2 1 3 6 6 6 3 C2H2-type zinc ribbon Pkinase PF00069.25 EGF84316.1 - 5.8e-63 212.7 0.0 7.2e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84316.1 - 4e-40 137.7 0.0 4.9e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF84316.1 - 1.6e-06 27.6 0.0 5.8e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGF84316.1 - 2.1e-05 23.5 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGF84316.1 - 0.00018 20.6 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGF84316.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF620 PF04788.12 EGF84316.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF620) FbpA PF05833.11 EGF84317.1 - 2e-33 115.9 17.8 7.5e-32 110.7 17.8 2.1 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 EGF84317.1 - 7e-31 106.3 0.2 7e-31 106.3 0.2 2.0 2 0 0 2 2 2 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EGF84317.1 - 6.5e-22 78.2 0.3 3e-21 76.1 0.1 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain DASH_Dad2 PF08654.10 EGF84317.1 - 0.011 16.1 2.6 0.011 16.1 2.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Glutaredoxin2_C PF04399.13 EGF84317.1 - 0.015 15.2 5.8 0.086 12.7 1.1 3.0 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain FapA PF03961.13 EGF84317.1 - 0.045 12.3 1.4 0.073 11.7 1.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lectin_N PF03954.14 EGF84317.1 - 0.13 12.0 1.4 0.46 10.2 1.4 2.0 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain RICH PF05062.12 EGF84317.1 - 0.28 11.6 4.8 0.26 11.7 1.7 2.4 2 0 0 2 2 2 0 RICH domain GIDA_assoc PF13932.6 EGF84317.1 - 1.7 8.8 7.0 0.22 11.7 2.5 1.8 2 0 0 2 2 2 0 GidA associated domain DUF16 PF01519.16 EGF84317.1 - 2.8 8.5 6.1 1.4 9.4 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 RRM_1 PF00076.22 EGF84318.1 - 1.6e-25 88.7 0.1 1.7e-12 46.9 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 EGF84318.1 - 3e-20 70.7 0.1 0.00021 20.8 0.0 5.1 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 EGF84318.1 - 4.6e-06 26.4 0.1 0.04 13.8 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EGF84318.1 - 0.017 14.7 0.1 1.4 8.5 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Clathrin PF00637.20 EGF84319.1 - 2.9e-16 59.6 1.8 6.4e-13 48.8 1.5 3.2 2 1 1 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 EGF84319.1 - 2.5e-11 43.6 0.4 5.3e-11 42.6 0.4 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EGF84319.1 - 5.5e-08 32.7 9.8 1.1e-07 31.8 9.8 1.5 1 0 0 1 1 1 1 Zinc-finger Vps39_2 PF10367.9 EGF84319.1 - 0.0011 19.4 1.4 0.0027 18.1 1.4 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 EGF84319.1 - 0.0018 18.1 8.8 0.0043 16.9 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF84319.1 - 0.064 13.2 8.3 0.14 12.1 8.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.22 EGF84319.1 - 0.18 11.7 6.7 0.45 10.5 6.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 EGF84319.1 - 0.2 12.0 8.0 0.54 10.6 8.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 EGF84319.1 - 2.4 8.5 6.5 7.7 6.9 6.5 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGF84319.1 - 3.3 7.6 8.2 7.2 6.6 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGF84319.1 - 5.2 7.2 7.6 11 6.1 7.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Rxt3 PF08642.10 EGF84320.1 - 3.2e-27 95.8 0.0 3.2e-27 95.8 0.0 2.7 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EGF84320.1 - 0.1 12.7 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 LCCL domain Tubulin-binding PF00418.19 EGF84323.1 - 3.8e-77 253.9 41.9 1.3e-10 41.1 0.3 8.2 8 0 0 8 8 8 8 Tau and MAP protein, tubulin-binding repeat TEP1_N PF05386.11 EGF84323.1 - 0.017 14.7 4.0 42 3.8 0.1 4.7 7 0 0 7 7 7 0 TEP1 N-terminal domain YkpC PF17447.2 EGF84323.1 - 0.2 12.5 3.4 4e+02 2.3 0.0 5.8 7 0 0 7 7 7 0 Uncharacterized YkpC-like GTP_cyclohydroI PF01227.22 EGF84324.1 - 2.8e-77 258.2 0.5 3.3e-77 258.0 0.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGF84324.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 QueF-like protein DSPc PF00782.20 EGF84325.1 - 3.8e-29 101.2 0.2 4.2e-29 101.0 0.2 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGF84325.1 - 3.7e-06 26.7 0.1 4e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 EGF84325.1 - 0.00031 19.8 0.3 0.00038 19.5 0.3 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.6 EGF84325.1 - 0.00048 20.3 0.0 0.0007 19.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EGF84325.1 - 0.0005 20.3 0.1 0.00056 20.2 0.1 1.1 1 0 0 1 1 1 1 Rit1 DUSP-like domain YafO_toxin PF13957.6 EGF84325.1 - 0.0024 17.9 0.2 0.0032 17.5 0.2 1.2 1 0 0 1 1 1 1 Toxin YafO, type II toxin-antitoxin system RPT PF13446.6 EGF84325.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein Myb_DNA-binding PF00249.31 EGF84326.1 - 2.3e-09 37.3 2.8 6.7e-09 35.8 0.3 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF84326.1 - 0.0003 21.0 1.0 0.69 10.2 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGF84326.1 - 0.0011 19.3 1.4 0.002 18.4 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain ETF PF01012.21 EGF84327.1 - 7.5e-50 169.3 1.5 1e-49 168.9 1.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pkinase PF00069.25 EGF84328.1 - 1.1e-21 77.4 0.0 2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EGF84328.1 - 2.5e-14 53.4 5.5 2.2e-07 31.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 EGF84328.1 - 9.2e-13 47.3 0.1 0.0043 17.2 0.0 4.9 4 0 0 4 4 4 4 HEAT repeat Pkinase_Tyr PF07714.17 EGF84328.1 - 3.5e-09 36.3 0.0 5.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EGF84328.1 - 9.6e-08 32.3 0.0 0.01 16.2 0.0 3.6 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGF84328.1 - 2.1e-05 24.9 0.0 0.18 12.3 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat Kinase-like PF14531.6 EGF84328.1 - 0.0018 17.7 0.0 0.0054 16.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like N_formyltrans_C PF18216.1 EGF84328.1 - 0.0031 17.1 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 N-formyltransferase dimerization C-terminal domain Cnd1 PF12717.7 EGF84328.1 - 0.006 16.6 1.2 0.14 12.2 0.1 3.1 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 EGF84328.1 - 0.0072 15.9 0.6 1.3 8.5 0.1 2.7 3 0 0 3 3 3 1 Tti2 family PQQ_3 PF13570.6 EGF84328.1 - 0.057 13.9 1.3 7.8 7.1 0.0 3.1 3 0 0 3 3 2 0 PQQ-like domain PQQ PF01011.21 EGF84328.1 - 0.068 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat RGS PF00615.19 EGF84329.1 - 9.3e-14 51.7 0.1 2.5e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain POX PF07526.11 EGF84329.1 - 0.23 12.0 2.4 0.56 10.8 0.7 2.6 1 1 1 2 2 2 0 Associated with HOX MRC1 PF09444.10 EGF84331.1 - 1.4e-27 97.0 12.5 1.4e-27 97.0 12.5 6.5 7 1 0 7 7 7 1 MRC1-like domain Myb_DNA-binding PF00249.31 EGF84331.1 - 1.5e-06 28.3 0.1 3.8e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGF84331.1 - 5.4e-05 23.4 2.4 7.4e-05 22.9 0.5 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGF84331.1 - 0.004 17.3 1.0 0.015 15.5 1.0 1.9 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 WD40 PF00400.32 EGF84332.1 - 0.0071 17.2 2.3 11 7.1 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat LRR_9 PF14580.6 EGF84333.1 - 3e-27 95.2 20.9 3.6e-17 62.4 7.1 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 EGF84333.1 - 1.5e-15 57.1 41.1 2.3e-06 27.8 4.1 6.5 3 3 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGF84333.1 - 4.4e-11 42.4 33.9 0.00015 21.4 3.8 5.2 2 1 1 5 5 5 4 Leucine rich repeat Glyco_hydr_30_2 PF14587.6 EGF84335.1 - 4e-13 49.7 0.3 4e-13 49.7 0.3 2.5 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 WD40 PF00400.32 EGF84336.1 - 2e-42 142.4 25.9 1.1e-06 29.3 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84336.1 - 1.6e-10 41.2 2.4 0.017 15.4 0.0 5.8 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGF84336.1 - 1.2e-07 31.4 1.1 1.9e-06 27.4 1.0 2.8 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 EGF84336.1 - 7.8e-07 28.1 10.9 0.69 8.5 0.1 6.3 2 2 5 7 7 7 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGF84336.1 - 0.00016 21.4 0.3 0.4 10.2 0.0 3.1 1 1 2 3 3 3 2 PQQ-like domain Frtz PF11768.8 EGF84336.1 - 0.00025 19.5 0.0 0.00054 18.4 0.0 1.5 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 EGF84336.1 - 0.0039 16.0 2.8 1.2 7.9 1.8 4.2 2 1 0 2 2 2 1 Nup133 N terminal like PALB2_WD40 PF16756.5 EGF84336.1 - 0.004 16.1 6.3 3.9 6.3 0.0 5.1 1 1 5 6 6 6 2 Partner and localizer of BRCA2 WD40 domain DUF5046 PF16465.5 EGF84336.1 - 0.0045 16.5 0.1 6 6.2 0.0 3.4 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) PQQ PF01011.21 EGF84336.1 - 0.028 14.3 0.0 85 3.3 0.0 4.5 5 0 0 5 5 5 0 PQQ enzyme repeat Ge1_WD40 PF16529.5 EGF84336.1 - 0.037 13.0 1.7 0.6 9.0 0.2 3.1 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EGF84336.1 - 0.12 12.9 1.1 17 6.0 0.2 4.0 4 0 0 4 4 4 0 PQQ-like domain GST_N_3 PF13417.6 EGF84337.1 - 8.1e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGF84337.1 - 9.6e-13 48.3 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGF84337.1 - 8.1e-10 38.9 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGF84337.1 - 2.7e-07 30.7 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGF84337.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGF84337.1 - 0.0031 17.7 0.1 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGF84337.1 - 0.085 13.1 0.0 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin RrnaAD PF00398.20 EGF84338.1 - 6e-62 209.1 0.0 7.6e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGF84338.1 - 8.2e-06 26.4 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGF84338.1 - 0.0018 18.1 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EGF84338.1 - 0.0024 18.5 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF84338.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGF84338.1 - 0.046 14.5 0.0 0.092 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGF84338.1 - 0.058 13.2 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 EGF84338.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 EGF84338.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EGF84338.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGF84338.1 - 0.22 10.8 0.1 0.64 9.3 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Sedlin_N PF04628.13 EGF84339.1 - 1.2e-20 74.0 0.4 3.7e-20 72.4 0.4 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGF84339.1 - 0.0073 16.2 0.1 0.0086 16.0 0.1 1.3 1 1 0 1 1 1 1 Sybindin-like family KH_1 PF00013.29 EGF84341.1 - 1.4e-39 133.8 8.5 3.1e-15 55.7 1.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGF84341.1 - 4e-11 42.6 2.7 0.0089 15.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGF84341.1 - 5.7e-08 32.5 1.3 0.12 12.3 0.1 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EGF84341.1 - 2.2e-06 27.5 0.1 0.00098 19.1 0.0 2.7 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 EGF84341.1 - 0.00026 21.0 6.4 0.12 12.5 0.0 3.5 3 0 0 3 3 3 2 NusA-like KH domain DUF2040 PF09745.9 EGF84343.1 - 1.3e-32 112.3 16.1 1.3e-32 112.3 16.1 4.1 3 1 2 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF3301 PF11743.8 EGF84343.1 - 2.3 8.0 5.1 0.6 9.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) GAT PF03127.14 EGF84344.1 - 3.3e-07 30.5 1.4 8.9e-07 29.1 1.4 1.8 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EGF84344.1 - 0.045 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 VHS domain UCH PF00443.29 EGF84345.1 - 1.5e-60 204.9 1.1 1.5e-60 204.9 1.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGF84345.1 - 2.8e-15 56.7 3.7 3e-11 43.5 0.2 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF2791 PF10923.8 EGF84345.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) WD40 PF00400.32 EGF84346.1 - 0.0017 19.1 7.9 33 5.6 2.3 5.4 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84346.1 - 0.093 13.0 0.0 4.1 7.8 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_4 PF12146.8 EGF84347.1 - 1.5e-11 44.0 0.1 9.5e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGF84347.1 - 3.1e-07 31.2 0.1 4.2e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGF84347.1 - 4.8e-07 29.7 0.4 0.00011 21.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 EGF84347.1 - 0.0021 17.8 0.2 0.0033 17.2 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 EGF84347.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 EGF84347.1 - 0.13 11.8 0.1 0.35 10.4 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) SH3_1 PF00018.28 EGF84348.1 - 7e-11 41.6 0.1 1.6e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 EGF84348.1 - 4.7e-10 39.6 0.4 4.7e-10 39.6 0.4 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EGF84348.1 - 7.1e-09 35.4 0.2 1.2e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGF84348.1 - 2.1e-08 33.7 0.1 3.9e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 EGF84348.1 - 0.0007 19.4 0.3 0.0016 18.2 0.3 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_3 PF08239.11 EGF84348.1 - 0.0021 18.3 0.3 0.004 17.4 0.3 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain hSH3 PF14603.6 EGF84348.1 - 0.0037 17.7 0.1 0.022 15.2 0.0 2.4 2 0 0 2 2 2 1 Helically-extended SH3 domain Latarcin PF10279.9 EGF84348.1 - 0.0085 16.5 9.5 0.2 12.1 2.4 3.3 3 1 0 3 3 3 2 Latarcin precursor Curto_V2 PF07325.11 EGF84348.1 - 0.15 11.9 3.7 0.32 10.9 3.0 1.9 1 1 0 1 1 1 0 Curtovirus V2 protein DASH_Duo1 PF08651.10 EGF84348.1 - 0.42 10.4 9.9 0.36 10.6 0.4 3.5 2 1 0 2 2 2 0 DASH complex subunit Duo1 T4SS PF07996.11 EGF84348.1 - 2.6 8.4 23.3 0.92 9.9 17.9 2.4 2 1 0 2 2 2 0 Type IV secretion system proteins DUF948 PF06103.11 EGF84348.1 - 3.8 7.8 5.7 4.6 7.6 1.3 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 EGF84348.1 - 4.1 7.5 15.3 0.76 9.9 2.6 3.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCPsignal PF00015.21 EGF84348.1 - 7.2 6.4 13.1 1.6 8.5 3.5 3.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TPR_MLP1_2 PF07926.12 EGF84348.1 - 7.3 6.7 26.6 0.024 14.7 13.4 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 EGF84348.1 - 9.9 6.5 11.6 0.12 12.6 1.9 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) RRM_1 PF00076.22 EGF84350.1 - 2.6e-11 43.2 0.2 3.8e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGF84350.1 - 3.3e-09 36.4 10.0 6e-05 22.9 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EGF84350.1 - 0.00042 20.1 0.5 0.00042 20.1 0.5 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGF84350.1 - 0.0086 16.0 4.7 0.78 9.7 0.3 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 EGF84350.1 - 0.017 14.8 10.4 0.047 13.4 1.3 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EGF84350.1 - 0.029 14.2 6.1 0.052 13.4 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGF84350.1 - 0.052 13.3 6.3 1.1 9.0 2.3 2.4 2 0 0 2 2 2 0 Zinc knuckle NPR3 PF03666.13 EGF84350.1 - 0.08 11.7 0.8 0.11 11.2 0.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRM_7 PF16367.5 EGF84350.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Ribosomal_L28e PF01778.17 EGF84351.1 - 2.2e-37 128.3 1.2 2.2e-37 128.3 1.2 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGF84351.1 - 1.9e-24 86.2 15.1 1.9e-24 86.2 15.1 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGF84351.1 - 9.5e-07 28.5 15.2 1.2e-06 28.1 15.2 1.1 1 0 0 1 1 1 1 BUD22 Exonuc_VII_L PF02601.15 EGF84351.1 - 0.042 13.4 1.8 0.062 12.9 1.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EGF84351.1 - 0.046 13.1 0.7 0.063 12.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YL1 PF05764.13 EGF84351.1 - 7 6.7 24.6 0.25 11.4 16.5 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Peptidase_C2 PF00648.21 EGF84352.1 - 1.5e-49 168.6 0.1 3e-49 167.6 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 EGF84352.1 - 8.3e-23 81.2 0.1 3e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Calpain large subunit, domain III C2 PF00168.30 EGF84352.1 - 0.0078 16.5 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 EGF84353.1 - 1.3e-12 47.7 0.0 7.9e-12 45.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGF84353.1 - 2.8e-05 24.1 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGF84353.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGF84353.1 - 0.0033 17.0 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGF84353.1 - 0.006 15.9 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGF84353.1 - 0.0077 15.5 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF84353.1 - 0.0079 15.0 0.6 0.011 14.6 0.6 1.4 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGF84353.1 - 0.008 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGF84353.1 - 0.042 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-PolyVal PF18762.1 EGF84353.1 - 0.045 13.7 1.2 0.45 10.5 0.1 2.3 3 0 0 3 3 3 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Dimer_Tnp_hAT PF05699.14 EGF84354.1 - 3.4e-19 68.4 0.1 3.7e-19 68.3 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.26 EGF84355.1 - 7.9e-07 29.2 17.3 5.7e-05 23.4 2.1 3.4 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGF84355.1 - 1.2e-05 25.2 0.5 1.2e-05 25.2 0.5 2.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGF84355.1 - 2.5e-05 24.5 2.1 2.5e-05 24.5 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGF84355.1 - 0.00016 22.2 1.0 0.00016 22.2 1.0 3.1 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGF84355.1 - 0.0033 17.7 1.9 0.0078 16.5 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGF84355.1 - 0.031 14.2 0.8 0.083 12.8 0.8 1.9 1 1 0 1 1 1 0 zinc-finger of a C2HC-type zf-UDP PF14569.6 EGF84355.1 - 0.036 14.2 2.4 0.57 10.3 2.4 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-met PF12874.7 EGF84355.1 - 0.088 13.2 3.4 0.1 13.1 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGF84355.1 - 0.18 12.2 5.5 0.16 12.3 1.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EGF84355.1 - 1.2 9.7 7.1 0.4 11.2 0.8 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Tax PF02959.16 EGF84356.1 - 0.05 13.1 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 HTLV Tax Syntaxin_2 PF14523.6 EGF84356.1 - 0.27 11.6 2.8 1.3 9.5 2.8 2.2 1 1 0 1 1 1 0 Syntaxin-like protein GTP_EFTU PF00009.27 EGF84357.1 - 9.9e-42 142.7 0.0 1.6e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGF84357.1 - 2.6e-29 101.8 0.5 1.3e-28 99.5 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGF84357.1 - 4.6e-11 42.9 3.2 5.1e-11 42.8 1.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGF84357.1 - 0.0027 17.8 0.0 0.026 14.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGF84357.1 - 0.0054 16.6 1.5 0.01 15.7 0.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Rho_GDI PF02115.17 EGF84358.1 - 4e-65 219.2 0.1 4.8e-65 219.0 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor FmiP_Thoc5 PF09766.9 EGF84359.1 - 5.3e-80 269.4 4.1 6.7e-80 269.1 4.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 MBOAT PF03062.19 EGF84360.1 - 5.2e-35 121.4 16.8 2.6e-33 115.8 16.7 2.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CRAL_TRIO PF00650.20 EGF84362.1 - 9.3e-20 70.9 0.0 6e-19 68.3 0.0 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain FH2 PF02181.23 EGF84363.1 - 7.6e-49 166.8 2.0 2.8e-48 164.9 2.0 1.8 1 1 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 EGF84363.1 - 9.7e-15 54.5 0.0 2.6e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGF84363.1 - 0.0082 16.0 0.0 0.032 14.0 0.0 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGF84363.1 - 0.0082 16.1 2.8 0.049 13.6 0.0 2.6 3 0 0 3 3 3 1 Tyrosine phosphatase family DUF4038 PF13204.6 EGF84363.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) DNA_methylase PF00145.17 EGF84364.1 - 3e-36 125.5 0.0 3.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Oxidored_molyb PF00174.19 EGF84365.1 - 1.8e-58 196.9 0.0 2.7e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGF84365.1 - 1.1e-29 103.3 0.4 2.2e-29 102.2 0.4 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EGF84365.1 - 2.4e-12 46.8 0.0 4.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RXT2_N PF08595.11 EGF84366.1 - 7.2e-08 32.6 0.0 9.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal 14-3-3 PF00244.20 EGF84366.1 - 0.065 12.7 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein Glyco_hydro_31 PF01055.26 EGF84369.1 - 1.1e-109 367.5 0.2 1.4e-109 367.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGF84369.1 - 1e-16 61.0 0.5 5.1e-16 58.8 0.5 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like HECT PF00632.25 EGF84370.1 - 3.4e-85 286.2 0.1 4.4e-85 285.9 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ThiJ_like PF17124.5 EGF84371.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 ThiJ/PfpI family-like S36_mt PF10937.8 EGF84372.1 - 2.3e-08 35.6 0.0 0.0085 17.7 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial COS PF18568.1 EGF84372.1 - 0.062 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain eIF2A PF08662.11 EGF84373.1 - 3.2e-76 255.5 3.9 6.6e-75 251.3 0.6 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EGF84373.1 - 0.29 12.1 1.4 7.5 7.6 0.2 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Alginate_lyase PF05426.12 EGF84375.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Alginate lyase CENP-F_leu_zip PF10473.9 EGF84376.1 - 5.8e-06 26.4 16.6 5.8e-06 26.4 16.6 3.9 2 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Flg_hook PF02120.16 EGF84376.1 - 0.029 14.2 1.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Ig_GlcNase PF18368.1 EGF84376.1 - 0.11 12.7 0.5 0.64 10.2 0.1 2.5 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Cnn_1N PF07989.11 EGF84376.1 - 0.55 10.4 28.9 1.9 8.7 1.6 4.8 3 1 2 5 5 5 0 Centrosomin N-terminal motif 1 GAS PF13851.6 EGF84376.1 - 1.7 8.0 40.0 27 4.0 3.5 4.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EGF84376.1 - 4.7 6.7 31.1 1.7 8.1 10.6 3.5 2 1 0 3 3 3 0 Intermediate filament protein Aminotran_5 PF00266.19 EGF84377.1 - 3.2e-31 108.6 0.0 3.9e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V BPL_LplA_LipB PF03099.19 EGF84378.1 - 2e-07 31.0 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Amidohydro_1 PF01979.20 EGF84379.1 - 3.9e-75 253.3 0.2 4.7e-75 253.0 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGF84379.1 - 1.6e-07 31.2 0.4 0.0002 21.0 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Colipase-like PF15083.6 EGF84379.1 - 0.18 11.9 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 Colipase-like Ribosomal_L27 PF01016.19 EGF84380.1 - 2e-33 114.2 0.1 2.3e-33 114.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Zip PF02535.22 EGF84381.1 - 5.1e-32 111.4 22.4 3.9e-24 85.5 5.0 2.9 2 1 1 3 3 3 3 ZIP Zinc transporter ThiF PF00899.21 EGF84382.1 - 1.1e-62 211.6 0.1 1.5e-62 211.2 0.1 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGF84382.1 - 1e-11 45.3 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 EGF84382.1 - 0.00071 19.6 0.1 0.0042 17.1 0.1 2.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGF84382.1 - 0.036 14.3 1.4 0.26 11.6 1.4 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF2034 PF10356.9 EGF84382.1 - 0.083 12.3 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) CTNNBL PF08216.11 EGF84383.1 - 1.6e-29 102.2 0.2 3.6e-29 101.0 0.2 1.7 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.8 EGF84383.1 - 0.0057 16.6 0.9 0.31 11.0 0.0 3.1 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm_3 PF16186.5 EGF84383.1 - 0.015 14.9 0.0 0.054 13.1 0.0 1.9 1 0 0 1 1 1 0 Atypical Arm repeat GatB_Yqey PF02637.18 EGF84383.1 - 0.018 14.9 0.2 0.049 13.5 0.2 1.8 1 0 0 1 1 1 0 GatB domain Phage_DsbA PF11126.8 EGF84383.1 - 0.066 13.4 0.3 16 5.8 0.1 3.2 2 1 0 2 2 2 0 Transcriptional regulator DsbA SNAP PF14938.6 EGF84384.1 - 2.5e-33 115.7 12.9 3.6e-33 115.2 12.9 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGF84384.1 - 0.00027 21.2 14.6 0.026 14.8 0.3 3.7 2 2 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGF84384.1 - 0.0096 16.7 11.4 3.4 8.7 0.1 5.6 3 1 4 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF84384.1 - 0.0099 15.8 14.0 1.3 9.2 2.3 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGF84384.1 - 0.052 13.8 6.7 0.15 12.3 3.5 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 YchF-GTPase_C PF06071.13 EGF84384.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF933) NSF PF02071.20 EGF84384.1 - 0.057 14.1 21.3 18 6.7 1.1 6.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat DUF1778 PF08681.11 EGF84384.1 - 0.19 11.7 2.9 0.59 10.1 2.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1778) Glyco_H_20C_C PF18088.1 EGF84384.1 - 0.24 11.2 2.3 0.23 11.3 0.7 1.7 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain TPR_2 PF07719.17 EGF84384.1 - 0.24 11.6 19.6 0.93 9.8 0.2 6.0 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGF84384.1 - 1.6 9.5 14.1 1.1e+02 3.6 0.0 4.1 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGF84384.1 - 2.2 8.4 12.4 4 7.6 0.8 4.0 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EGF84384.1 - 5.9 7.4 13.6 16 6.0 0.7 5.3 3 1 4 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGF84384.1 - 6.5 7.6 16.7 24 5.8 2.5 5.7 3 1 3 6 6 5 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EGF84385.1 - 3.5e-25 87.9 0.0 3.9e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ANTAR PF03861.14 EGF84385.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ANTAR domain CDP-OH_P_transf PF01066.21 EGF84386.1 - 1.4e-16 61.0 0.1 1.4e-16 61.0 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4791 PF16039.5 EGF84386.1 - 0.0079 15.7 0.9 0.043 13.3 0.1 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4791) DUF3810 PF12725.7 EGF84386.1 - 3.6 6.8 6.3 0.7 9.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2703 PF10865.8 EGF84387.1 - 0.14 12.4 0.1 0.25 11.5 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) RHSP PF07999.11 EGF84388.1 - 0.0081 15.0 3.0 0.0085 15.0 0.4 2.1 2 1 0 2 2 2 1 Retrotransposon hot spot protein DUF2014 PF09427.10 EGF84389.1 - 0.031 13.6 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) PI3_PI4_kinase PF00454.27 EGF84390.1 - 1.3e-44 152.9 0.0 1.5e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGF84390.1 - 5.8e-16 58.0 0.0 8.9e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EGF84391.1 - 1.8e-30 106.4 0.6 1.8e-30 106.4 0.6 2.5 3 0 0 3 3 3 1 FAT domain UME PF08064.13 EGF84391.1 - 1.9e-19 69.5 6.0 2e-19 69.4 1.4 3.2 3 0 0 3 3 3 1 UME (NUC010) domain TPR_14 PF13428.6 EGF84391.1 - 0.00045 20.8 4.5 0.44 11.5 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF84391.1 - 0.0016 18.9 0.0 0.014 15.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGF84391.1 - 0.0031 17.5 0.0 0.018 15.1 0.0 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF84391.1 - 0.019 14.8 0.0 0.089 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat GDC-P PF02347.16 EGF84391.1 - 0.024 13.5 0.1 0.044 12.6 0.1 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein TPR_7 PF13176.6 EGF84391.1 - 0.041 13.9 3.7 0.2 11.8 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Radical_SAM_C PF16199.5 EGF84391.1 - 0.062 13.3 0.2 0.55 10.3 0.1 2.6 2 0 0 2 2 2 0 Radical_SAM C-terminal domain SlyX PF04102.12 EGF84391.1 - 0.083 13.5 2.0 0.34 11.6 0.3 3.0 2 1 0 2 2 2 0 SlyX TPR_11 PF13414.6 EGF84391.1 - 0.17 11.6 0.1 0.45 10.2 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 EGF84391.1 - 0.36 11.1 4.4 0.3 11.4 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 EGF84392.1 - 1.4e-20 73.2 8.6 2.9e-05 24.8 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGF84392.1 - 2.4e-05 24.5 0.1 0.026 14.8 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGF84392.1 - 3.7e-05 22.6 2.0 0.001 17.8 0.1 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGF84392.1 - 0.084 12.2 0.1 27 4.0 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain zf-CCCH PF00642.24 EGF84393.1 - 8.1e-10 38.4 3.0 2e-09 37.1 3.0 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EGF84393.1 - 4e-07 29.8 5.8 7.3e-07 29.0 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF84393.1 - 7.9e-06 25.7 10.3 1.4e-05 25.0 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF84393.1 - 8.3e-06 25.7 7.7 1.8e-05 24.6 7.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EGF84393.1 - 1.2e-05 25.1 5.6 3e-05 23.9 5.6 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 EGF84393.1 - 1.8e-05 24.5 9.4 3.9e-05 23.4 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGF84393.1 - 3.5e-05 23.6 10.1 7.3e-05 22.5 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGF84393.1 - 0.00024 21.3 8.5 0.00024 21.3 8.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_4 PF18044.1 EGF84393.1 - 0.0022 17.7 3.8 0.0022 17.7 3.8 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGF84393.1 - 0.0047 17.4 2.3 0.015 15.8 2.3 1.9 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-RING_10 PF16685.5 EGF84393.1 - 0.012 15.7 3.8 0.012 15.7 3.8 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EGF84393.1 - 0.081 12.8 4.0 0.14 12.0 4.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EGF84393.1 - 0.26 11.2 7.5 0.53 10.2 7.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGF84393.1 - 0.28 11.4 12.4 0.056 13.6 8.8 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING KIAA1430 PF13879.6 EGF84394.1 - 3.6e-15 56.6 7.7 3.6e-15 56.6 7.7 3.3 3 2 0 3 3 3 1 KIAA1430 homologue Sugarporin_N PF11471.8 EGF84395.1 - 0.38 10.8 5.6 2.5 8.1 0.5 2.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension SPRY PF00622.28 EGF84396.1 - 9.3e-23 80.6 0.0 1.5e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 EGF84396.1 - 2.1e-13 50.4 2.2 1.2e-05 25.3 0.7 2.4 1 1 1 2 2 2 2 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGF84396.1 - 0.036 14.0 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 LisH AAA PF00004.29 EGF84397.1 - 0.00018 21.9 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGF84397.1 - 0.0002 21.7 0.0 0.00051 20.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EGF84397.1 - 0.0014 18.4 1.5 0.048 13.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGF84397.1 - 0.0027 18.1 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGF84397.1 - 0.0033 17.0 0.0 0.0085 15.6 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGF84397.1 - 0.0063 17.1 0.0 0.017 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGF84397.1 - 0.012 15.8 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGF84397.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGF84397.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGF84397.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGF84397.1 - 0.25 11.0 0.0 0.43 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2703 PF10865.8 EGF84398.1 - 0.15 12.3 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) RHSP PF07999.11 EGF84399.1 - 0.013 14.4 0.3 0.082 11.7 0.3 1.9 1 1 0 1 1 1 0 Retrotransposon hot spot protein Prominin PF05478.11 EGF84400.1 - 1.6e-16 59.5 10.4 5.3e-16 57.8 4.0 2.1 2 0 0 2 2 2 2 Prominin Prominin PF05478.11 EGF84401.1 - 7.2e-11 40.8 3.7 1.3e-08 33.4 0.2 2.3 2 0 0 2 2 2 2 Prominin Shisa PF13908.6 EGF84401.1 - 0.0027 18.0 2.2 0.0038 17.5 0.3 2.2 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator NnrS PF05940.12 EGF84401.1 - 0.0027 17.1 0.9 0.0027 17.1 0.9 2.1 2 0 0 2 2 2 1 NnrS protein LXG PF04740.12 EGF84401.1 - 0.044 13.5 3.7 0.35 10.6 0.3 2.9 3 0 0 3 3 3 0 LXG domain of WXG superfamily DUF1218 PF06749.12 EGF84401.1 - 1.8 9.1 13.8 1.6 9.3 7.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) ACC_central PF08326.12 EGF84402.1 - 1.3e-199 665.0 0.0 1.6e-199 664.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGF84402.1 - 2.1e-172 574.2 0.0 3.1e-172 573.7 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGF84402.1 - 1.2e-52 178.4 0.0 2.3e-52 177.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGF84402.1 - 3.1e-28 98.5 0.1 6.7e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGF84402.1 - 2.3e-21 75.9 0.0 5.3e-20 71.5 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGF84402.1 - 3.5e-13 49.2 0.0 8.7e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EGF84402.1 - 0.004 17.2 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain UQ_con PF00179.26 EGF84403.1 - 2e-46 157.1 0.1 2.5e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGF84403.1 - 2e-05 24.8 0.1 2.9e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EGF84403.1 - 0.029 14.2 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 EGF84403.1 - 0.037 13.7 0.1 0.11 12.2 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 VTC PF09359.10 EGF84404.1 - 4.8e-94 314.8 0.0 7.8e-94 314.1 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EGF84404.1 - 8.2e-17 62.2 11.0 7.3e-07 29.4 0.2 3.7 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 EGF84404.1 - 1.5e-14 54.2 2.3 2.9e-14 53.2 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cyt_c_ox_IV PF12270.8 EGF84404.1 - 0.038 14.1 0.4 0.072 13.2 0.4 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV GATA PF00320.27 EGF84406.1 - 2.5e-10 39.8 5.0 7.2e-10 38.3 5.0 1.8 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 EGF84406.1 - 0.083 12.9 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon XPA_C PF05181.12 EGF84407.1 - 6.5e-22 77.2 1.9 6.5e-22 77.2 1.9 1.8 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 EGF84407.1 - 0.011 15.7 4.8 0.011 15.7 4.8 1.8 2 0 0 2 2 2 0 XPA protein N-terminal Trm112p PF03966.16 EGF84407.1 - 0.067 13.8 0.9 0.16 12.6 0.9 1.8 1 1 0 1 1 1 0 Trm112p-like protein Cytochrom_B558a PF05038.13 EGF84408.1 - 2.2e-09 37.2 6.0 5.2e-08 32.7 0.6 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit DUF2475 PF10629.9 EGF84409.1 - 1.1e-19 70.4 3.3 1.6e-07 31.5 0.1 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF2475) Peptidase_M28 PF04389.17 EGF84410.1 - 6.2e-33 114.2 0.2 2.4e-32 112.2 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M28 DUF572 PF04502.13 EGF84411.1 - 3.1e-68 230.8 0.0 3.6e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 EGF84411.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) G-patch PF01585.23 EGF84412.1 - 1.2e-13 50.7 1.6 2.5e-13 49.7 1.6 1.6 1 0 0 1 1 1 1 G-patch domain Tudor_2 PF18104.1 EGF84412.1 - 0.017 14.8 0.0 0.051 13.3 0.0 1.9 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Kinesin_assoc PF16183.5 EGF84412.1 - 0.8 9.8 5.3 0.22 11.7 1.5 1.9 2 0 0 2 2 2 0 Kinesin-associated EST1 PF10374.9 EGF84414.1 - 5e-11 43.4 0.7 5e-11 43.4 0.7 3.0 3 1 0 3 3 3 1 Telomerase activating protein Est1 PIN_4 PF13638.6 EGF84414.1 - 3.2e-09 37.2 0.0 1.2e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 EGF84414.1 - 9.7e-09 35.1 10.0 1.8e-08 34.2 7.7 2.4 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain PIH1_CS PF18201.1 EGF84414.1 - 0.00061 20.2 0.0 0.0034 17.8 0.0 2.2 2 0 0 2 2 2 1 PIH1 CS-like domain ThiF PF00899.21 EGF84415.1 - 6.9e-36 123.8 0.0 8.8e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGF84415.1 - 0.025 14.7 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase E1_4HB PF16191.5 EGF84415.1 - 0.062 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle STI1 PF17830.1 EGF84416.1 - 3.7e-12 46.0 2.5 8.7e-09 35.2 0.7 2.4 2 0 0 2 2 2 2 STI1 domain XPC-binding PF09280.11 EGF84416.1 - 0.31 10.8 3.6 0.79 9.5 3.6 1.7 1 0 0 1 1 1 0 XPC-binding domain Sedlin_N PF04628.13 EGF84418.1 - 1.5e-46 157.8 0.0 1.6e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGF84418.1 - 1.6e-10 41.1 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Peptidase_Mx1 PF15890.5 EGF84419.1 - 0.044 13.2 0.6 0.084 12.3 0.6 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase ANAPC3 PF12895.7 EGF84419.1 - 0.077 13.2 2.3 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGF84419.1 - 2.5 8.5 5.1 25 5.4 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Med14 PF08638.11 EGF84420.1 - 6.3e-58 195.4 0.2 1.4e-57 194.2 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 TB2_DP1_HVA22 PF03134.19 EGF84421.1 - 6.7e-19 67.6 8.7 1.3e-18 66.7 8.7 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HU-CCDC81_bac_1 PF18174.1 EGF84421.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 WD40 PF00400.32 EGF84422.1 - 0.013 16.3 0.2 0.34 11.8 0.1 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF561 PF04481.12 EGF84422.1 - 0.074 12.2 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Aldedh PF00171.22 EGF84423.1 - 3.7e-178 592.8 0.3 4.2e-178 592.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGF84423.1 - 0.00062 18.9 0.0 0.05 12.6 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) NAD_binding_11 PF14833.6 EGF84423.1 - 0.032 14.5 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SWIRM-assoc_3 PF16498.5 EGF84423.1 - 0.085 13.1 1.6 0.28 11.5 1.6 1.9 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal DNA_pol_B PF00136.21 EGF84424.1 - 3.3e-106 355.7 0.2 1e-105 354.2 0.2 1.9 1 1 1 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGF84424.1 - 2.7e-44 151.2 0.1 2.7e-44 151.2 0.1 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EGF84424.1 - 1.4e-41 142.8 0.0 2.5e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EGF84424.1 - 2.9e-20 72.1 2.1 7.6e-20 70.8 2.1 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EGF84424.1 - 0.0021 17.0 0.1 0.0041 16.0 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1729 PF08354.10 EGF84424.1 - 0.11 11.4 0.4 0.53 9.1 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1729) Bap31_Bap29_C PF18035.1 EGF84424.1 - 1.4 9.0 3.9 0.97 9.5 0.7 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain TSC22 PF01166.18 EGF84424.1 - 3.3 8.1 9.2 27 5.1 0.5 3.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Rpr2 PF04032.16 EGF84425.1 - 1e-20 73.8 1.5 1.7e-20 73.1 0.1 2.0 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.15 EGF84425.1 - 3.7 7.6 10.6 1.3 9.1 0.3 2.9 2 1 1 3 3 3 0 BED zinc finger Glyco_transf_20 PF00982.21 EGF84428.1 - 7.8e-195 648.0 0.0 8.8e-195 647.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EGF84428.1 - 0.0004 20.2 0.1 0.001 18.8 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGF84428.1 - 0.019 14.5 0.7 3.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 BTB PF00651.31 EGF84429.1 - 9.5e-07 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_L14e PF01929.17 EGF84432.1 - 3.5e-25 88.3 0.2 4.9e-25 87.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EGF84432.1 - 1.8e-05 24.5 3.7 3.8e-05 23.5 2.2 2.1 2 0 0 2 2 2 1 KOW motif MlaD PF02470.20 EGF84432.1 - 0.099 13.0 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 MlaD protein 60KD_IMP PF02096.20 EGF84433.1 - 3.9e-26 91.9 5.4 5.5e-26 91.4 5.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Tristanin_u2 PF16638.5 EGF84435.1 - 0.022 15.6 0.6 0.028 15.3 0.6 1.2 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers ATP-synt_C PF00137.21 EGF84436.1 - 1.2e-25 89.6 34.9 2e-14 53.7 8.2 3.1 3 0 0 3 3 3 2 ATP synthase subunit C COX6B PF02297.17 EGF84437.1 - 1.1e-14 54.4 4.0 4.1e-14 52.6 4.0 1.9 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF3763 PF12592.8 EGF84437.1 - 0.1 12.6 0.4 0.1 12.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) cNMP_binding PF00027.29 EGF84438.1 - 1.9e-14 53.5 0.0 9.4e-11 41.7 0.0 3.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Rib_5-P_isom_A PF06026.14 EGF84439.1 - 3.4e-57 192.8 0.0 4.6e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FKBP_C PF00254.28 EGF84440.1 - 2.8e-34 117.3 0.1 3.5e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ras PF00071.22 EGF84441.1 - 1.6e-52 177.4 0.0 1.8e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGF84441.1 - 3.7e-19 69.1 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGF84441.1 - 1.3e-07 31.3 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGF84441.1 - 0.0047 16.5 0.0 0.025 14.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Glyco_hydro_26 PF02156.15 EGF84442.1 - 1.9e-06 27.6 4.1 0.00016 21.3 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 EGF84442.1 - 0.016 14.7 0.1 0.035 13.6 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 EGF84442.1 - 0.094 12.3 0.1 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 EGF84442.1 - 0.1 12.8 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_6 PF13405.6 EGF84442.1 - 0.16 12.0 0.9 0.36 10.9 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain Sec23_helical PF04815.15 EGF84443.1 - 0.11 12.3 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain IQCJ-SCHIP1 PF15157.6 EGF84443.1 - 0.16 11.8 0.8 8.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif MCM_bind PF09739.9 EGF84444.1 - 8.8e-141 470.2 0.0 9.9e-139 463.4 0.0 2.0 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor RIFIN PF02009.16 EGF84446.1 - 1.1 9.1 8.2 5.2 6.9 8.2 2.1 1 1 0 1 1 1 0 Rifin Trypan_PARP PF05887.11 EGF84446.1 - 5.5 7.0 97.7 0.14 12.2 28.5 4.8 3 1 1 5 5 5 0 Procyclic acidic repetitive protein (PARP) Ost4 PF10215.9 EGF84447.1 - 0.019 14.8 0.8 0.04 13.7 0.8 1.5 1 0 0 1 1 1 0 Oligosaccaryltransferase Oxysterol_BP PF01237.18 EGF84448.1 - 1.3e-127 425.7 0.0 1.6e-127 425.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Methyltransf_25 PF13649.6 EGF84449.1 - 6.5e-19 68.4 0.0 1.6e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Dala_Dala_lig_C PF07478.13 EGF84449.1 - 2.2e-16 60.0 0.0 4.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_11 PF08241.12 EGF84449.1 - 5.2e-14 52.7 0.0 1.6e-13 51.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF84449.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF84449.1 - 1.2e-10 41.1 0.0 2.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGF84449.1 - 5.7e-09 36.6 0.0 1.7e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGF84449.1 - 1.4e-07 31.5 0.0 3.9e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGF84449.1 - 4.2e-05 23.2 0.0 8.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGF84449.1 - 0.0053 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EGF84449.1 - 0.045 12.7 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 EGF84449.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EGF84449.1 - 0.073 12.5 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase ATP-grasp_3 PF02655.14 EGF84449.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Methyltransf_15 PF09445.10 EGF84449.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.16 EGF84449.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_5 PF01795.19 EGF84449.1 - 0.2 11.1 0.0 0.62 9.5 0.0 1.7 2 0 0 2 2 2 0 MraW methylase family ATP-grasp_4 PF13535.6 EGF84450.1 - 1.1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGF84450.1 - 8.4e-05 22.2 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EGF84450.1 - 0.00093 18.8 0.0 0.0023 17.5 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGF84450.1 - 0.0025 17.1 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 EGF84450.1 - 0.008 15.7 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGF84450.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Prefoldin_2 PF01920.20 EGF84452.1 - 1.8e-18 66.5 4.5 2e-18 66.3 4.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF5384 PF17358.2 EGF84452.1 - 0.0015 18.6 4.2 0.019 15.0 4.2 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5384) Snf7 PF03357.21 EGF84452.1 - 0.0084 15.7 1.8 0.061 12.9 0.1 2.0 2 0 0 2 2 2 1 Snf7 DUF4709 PF15821.5 EGF84452.1 - 0.016 15.5 1.4 0.61 10.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) FTA4 PF13093.6 EGF84452.1 - 0.041 13.8 1.4 0.052 13.4 1.4 1.0 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CpxA_peri PF16527.5 EGF84452.1 - 0.045 14.1 0.5 0.058 13.8 0.5 1.1 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain Fib_alpha PF08702.10 EGF84452.1 - 0.23 11.6 2.0 0.29 11.3 2.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sterol_MT_C PF08498.10 EGF84453.1 - 5.5e-26 90.7 0.0 9.5e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGF84453.1 - 9.1e-16 58.3 0.0 1.7e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGF84453.1 - 5.4e-13 49.0 0.0 8.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGF84453.1 - 1.9e-12 47.7 0.0 3.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGF84453.1 - 2.7e-10 40.0 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGF84453.1 - 3.9e-07 30.0 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGF84453.1 - 1.5e-06 27.7 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGF84453.1 - 2.8e-06 28.0 0.0 6.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGF84453.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EGF84453.1 - 0.2 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L34 PF00468.17 EGF84454.1 - 3.3e-16 59.0 7.1 5.4e-16 58.3 7.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 SPX PF03105.19 EGF84455.1 - 0.053 13.4 5.4 0.069 13.1 5.4 1.2 1 0 0 1 1 1 0 SPX domain MFS_1 PF07690.16 EGF84456.1 - 2.4e-38 132.0 34.2 1.7e-35 122.6 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGF84456.1 - 3.4e-08 32.8 14.7 1.6e-07 30.6 14.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGF84456.1 - 4.1e-05 23.1 0.1 4.1e-05 23.1 0.1 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGF84456.1 - 0.00018 20.5 9.0 0.0018 17.2 8.9 2.4 1 1 0 1 1 1 1 MFS_1 like family ABC_tran PF00005.27 EGF84457.1 - 3.6e-30 105.3 0.0 7.7e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGF84457.1 - 2.3e-15 57.2 0.1 7.9e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGF84457.1 - 0.00027 20.2 26.9 0.0036 16.5 13.8 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_23 PF13476.6 EGF84457.1 - 0.00073 20.1 0.1 0.0013 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGF84457.1 - 0.058 13.1 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGF84457.1 - 0.063 13.0 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGF84457.1 - 0.071 12.9 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EGF84457.1 - 0.091 12.2 0.0 2.4 7.5 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 EGF84457.1 - 0.24 10.0 0.0 2.2 6.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain Cytochrom_C1 PF02167.15 EGF84459.1 - 6.1e-89 297.5 0.0 7.2e-89 297.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.21 EGF84459.1 - 0.018 16.2 0.3 0.042 15.0 0.3 1.7 1 1 0 1 1 1 0 Cytochrome c Cytochrome_CBB3 PF13442.6 EGF84459.1 - 0.022 15.1 0.1 0.043 14.1 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Pkinase PF00069.25 EGF84460.1 - 1.1e-55 188.9 0.0 1.2e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84460.1 - 6.6e-26 91.1 0.0 8.5e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGF84460.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like 5_nucleotid PF05761.14 EGF84460.1 - 0.055 12.4 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF1181 PF06680.11 EGF84460.1 - 0.086 12.7 0.1 0.18 11.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1181) APH PF01636.23 EGF84460.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGF84460.1 - 0.19 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain ATG13 PF10033.9 EGF84461.1 - 5.4e-69 232.5 0.0 9.3e-69 231.8 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 zinc_ribbon_6 PF14599.6 EGF84462.1 - 5.7e-18 64.7 0.9 5.7e-18 64.7 0.9 5.1 3 2 3 6 6 6 1 Zinc-ribbon zf-CHY PF05495.12 EGF84462.1 - 3.2e-17 62.8 21.5 3.2e-17 62.8 21.5 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EGF84462.1 - 6.7e-09 35.9 12.0 6.7e-09 35.9 12.0 5.1 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGF84462.1 - 3.4e-05 23.6 9.9 3.4e-05 23.6 9.9 5.9 2 1 5 7 7 7 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF84462.1 - 0.0017 18.2 5.3 0.0017 18.2 5.3 5.6 4 2 1 5 5 5 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGF84462.1 - 0.0023 17.7 16.8 0.0023 17.7 16.8 5.8 4 2 3 7 7 7 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF84462.1 - 0.0057 16.6 16.1 0.0057 16.6 16.1 6.7 3 2 2 5 5 5 2 zinc-RING finger domain zf-RING_11 PF17123.5 EGF84462.1 - 0.016 14.9 8.6 0.016 14.9 8.6 4.7 5 0 0 5 5 5 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EGF84462.1 - 0.03 14.4 12.2 0.03 14.4 12.2 4.1 5 1 0 5 5 5 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGF84463.1 - 2.3e-12 46.6 7.1 2.3e-12 46.6 7.1 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGF84463.1 - 1.9e-07 30.8 4.5 6.2e-07 29.2 4.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGF84463.1 - 4.5e-05 23.7 7.7 4.5e-05 23.7 7.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGF84463.1 - 0.63 9.9 11.9 0.4 10.6 4.4 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGF84463.1 - 1.2 9.2 13.1 0.037 14.0 7.1 1.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGF84463.1 - 7.7 6.6 8.8 2.1 8.5 2.5 2.9 2 1 1 3 3 3 0 RING-type zinc-finger AAR2 PF05282.11 EGF84464.1 - 6.7e-100 334.9 0.0 7.8e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein GDA1_CD39 PF01150.17 EGF84465.1 - 1.4e-112 376.5 0.0 1.6e-112 376.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Cript PF10235.9 EGF84466.1 - 3.7e-31 107.5 6.1 3.7e-31 107.5 6.1 1.3 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 EGF84466.1 - 0.00052 20.3 8.5 0.00052 20.3 8.5 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_15 PF17032.5 EGF84466.1 - 0.27 12.0 10.5 0.65 10.8 7.4 2.6 2 1 0 2 2 2 0 zinc-ribbon family Gin PF10764.9 EGF84466.1 - 0.45 10.5 8.3 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin DUF1272 PF06906.11 EGF84466.1 - 0.47 10.6 6.4 0.18 12.0 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.17 EGF84466.1 - 1.3 9.0 0.1 1.3 9.0 0.1 3.4 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger NOB1_Zn_bind PF08772.11 EGF84466.1 - 3.1 8.0 11.0 0.76 10.0 6.9 2.2 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-piccolo PF05715.13 EGF84466.1 - 8.1 6.7 11.4 3.9 7.7 7.4 2.3 2 1 0 2 2 2 0 Piccolo Zn-finger Caps_synth_CapC PF14102.6 EGF84467.1 - 0.47 10.9 10.2 0.11 13.0 0.8 2.5 2 1 0 2 2 2 0 Capsule biosynthesis CapC AAA PF00004.29 EGF84468.1 - 1.2e-87 291.1 0.0 8.1e-43 146.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGF84468.1 - 6.8e-24 83.4 4.2 2.7e-13 49.5 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGF84468.1 - 4.2e-14 52.6 0.1 3.3e-06 26.9 0.0 3.9 4 1 1 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGF84468.1 - 1.4e-12 48.1 0.0 8.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGF84468.1 - 4.9e-12 46.0 0.0 8.6e-06 25.8 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGF84468.1 - 1.2e-09 38.7 2.9 0.00097 19.6 0.5 4.4 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 EGF84468.1 - 3e-09 36.6 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EGF84468.1 - 4.9e-08 33.3 2.3 0.0035 17.6 0.0 4.5 2 2 1 4 4 4 1 AAA domain AAA_14 PF13173.6 EGF84468.1 - 3e-07 30.5 0.0 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGF84468.1 - 5.1e-07 30.0 0.0 0.0035 17.5 0.0 2.9 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EGF84468.1 - 5.3e-07 29.5 0.0 0.0049 16.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGF84468.1 - 5.7e-06 25.9 0.1 0.057 12.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGF84468.1 - 1.8e-05 25.1 0.0 0.35 11.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EGF84468.1 - 3e-05 23.7 4.2 0.84 9.2 0.1 4.3 2 2 1 3 3 3 2 AAA domain AAA_28 PF13521.6 EGF84468.1 - 0.00018 21.8 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGF84468.1 - 0.0002 21.9 0.0 0.064 13.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGF84468.1 - 0.00025 21.0 0.0 0.043 13.7 0.0 2.8 2 1 0 2 2 2 1 Rad17 P-loop domain ATPase PF06745.13 EGF84468.1 - 0.00038 19.9 0.0 0.12 11.7 0.0 2.7 2 1 0 2 2 2 1 KaiC TsaE PF02367.17 EGF84468.1 - 0.00048 20.1 0.2 0.44 10.6 0.0 2.7 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGF84468.1 - 0.00052 19.6 0.0 0.77 9.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGF84468.1 - 0.00055 19.7 0.1 0.53 10.0 0.0 4.1 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGF84468.1 - 0.00092 19.1 0.0 1.3 8.8 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGF84468.1 - 0.001 19.6 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 EGF84468.1 - 0.0016 18.2 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGF84468.1 - 0.0028 17.6 0.6 0.95 9.4 0.0 3.7 3 1 0 3 3 3 1 NACHT domain PhoH PF02562.16 EGF84468.1 - 0.0046 16.4 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activ_2 PF14532.6 EGF84468.1 - 0.0054 16.8 0.0 3.8 7.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Molydop_binding PF01568.21 EGF84468.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Zeta_toxin PF06414.12 EGF84468.1 - 0.019 14.3 0.0 0.86 8.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 EGF84468.1 - 0.021 13.9 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 IPT PF01745.16 EGF84468.1 - 0.025 14.0 0.1 0.6 9.5 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase DUF815 PF05673.13 EGF84468.1 - 0.044 12.9 0.0 6.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EGF84468.1 - 0.072 12.9 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGF84468.1 - 0.075 13.5 0.0 19 5.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 EGF84468.1 - 0.2 10.9 0.0 0.46 9.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) QCR10 PF09796.9 EGF84469.1 - 2.5e-14 53.1 0.1 3.4e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) WH2 PF02205.20 EGF84470.1 - 8.8e-08 31.7 3.5 2.8e-07 30.2 0.3 2.6 2 0 0 2 2 2 1 WH2 motif ParBc PF02195.18 EGF84471.1 - 0.0021 18.3 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain ASH PF15780.5 EGF84472.1 - 1.9e-07 31.2 0.3 0.023 14.9 0.0 4.7 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EGF84472.1 - 8.3e-05 22.8 1.7 0.011 15.9 0.1 3.8 4 1 0 4 4 4 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 EGF84472.1 - 0.0004 20.2 0.1 0.014 15.2 0.0 3.4 3 1 0 3 3 3 1 MSP (Major sperm protein) domain Alpha_adaptinC2 PF02883.20 EGF84472.1 - 0.078 13.3 0.2 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 Adaptin C-terminal domain CDC24_OB2 PF17245.2 EGF84472.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 Cdc6_C PF09079.11 EGF84473.1 - 1.6e-14 53.6 1.6 2.2e-14 53.2 0.3 2.0 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 EGF84473.1 - 9e-12 45.4 0.0 2.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGF84473.1 - 6.3e-11 42.8 0.0 1.9e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGF84473.1 - 3.9e-09 37.1 0.3 4.7e-07 30.4 0.3 2.7 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGF84473.1 - 1.8e-07 30.7 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 EGF84473.1 - 3.2e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 EGF84473.1 - 9.6e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EGF84473.1 - 0.0064 16.8 0.2 0.083 13.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGF84473.1 - 0.011 15.4 0.0 0.052 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGF84473.1 - 0.036 13.2 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 EGF84473.1 - 0.12 12.3 0.0 0.5 10.2 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Pro_isomerase PF00160.21 EGF84474.1 - 5.8e-28 98.1 0.0 8.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RAI1 PF08652.11 EGF84475.1 - 1.5e-21 76.3 0.0 2.5e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease S6PP_C PF08472.10 EGF84475.1 - 0.052 13.4 1.1 2.3 8.1 0.2 2.8 3 0 0 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal YqeY PF09424.10 EGF84477.1 - 2.2e-24 86.2 6.0 2.5e-24 86.0 6.0 1.0 1 0 0 1 1 1 1 Yqey-like protein Patatin PF01734.22 EGF84478.1 - 6.4e-09 36.3 0.5 0.0046 17.2 0.1 2.3 1 1 0 2 2 2 2 Patatin-like phospholipase F-box-like PF12937.7 EGF84479.1 - 0.1 12.5 9.0 0.07 13.0 3.3 3.2 3 0 0 3 3 3 0 F-box-like LRR_4 PF12799.7 EGF84479.1 - 0.17 12.4 6.2 2 9.0 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Acyl-CoA_dh_1 PF00441.24 EGF84480.1 - 2e-40 138.5 0.2 2.8e-40 138.0 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGF84480.1 - 2.4e-23 82.1 0.1 4.6e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EGF84480.1 - 3.2e-22 78.5 0.1 7.3e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGF84480.1 - 1.2e-19 71.0 0.0 3.1e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGF84480.1 - 5.9e-09 36.3 0.0 9.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pterin_4a PF01329.19 EGF84481.1 - 8.2e-19 67.6 0.1 9e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase fn3 PF00041.21 EGF84482.1 - 0.24 11.8 1.5 15 6.0 0.1 2.5 2 0 0 2 2 2 0 Fibronectin type III domain ADH_zinc_N PF00107.26 EGF84483.1 - 7.9e-26 90.6 0.3 1.3e-25 89.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGF84483.1 - 6.6e-20 72.5 0.0 1.4e-19 71.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGF84483.1 - 0.025 14.5 0.1 0.19 11.6 0.0 2.4 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain Rad51 PF08423.11 EGF84484.1 - 2.7e-16 59.6 0.0 9.5e-16 57.8 0.0 1.9 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 EGF84484.1 - 1.7e-05 24.3 0.0 4.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 EGF84484.1 - 9.3e-05 21.9 0.0 0.00034 20.0 0.0 1.8 2 0 0 2 2 2 1 KaiC RecA PF00154.21 EGF84484.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_18 PF13238.6 EGF84484.1 - 0.021 15.4 0.0 0.078 13.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 EGF84485.1 - 1.1e-155 519.0 12.5 1.3e-155 518.8 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TPR_14 PF13428.6 EGF84486.1 - 4.5e-11 42.6 4.7 0.0003 21.4 0.1 5.5 3 1 4 7 7 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGF84486.1 - 5.5e-10 38.7 0.4 2.4e-05 24.2 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGF84486.1 - 2.6e-09 37.4 0.0 0.0017 18.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGF84486.1 - 4.8e-08 32.5 0.0 7.3e-05 22.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGF84486.1 - 2e-07 31.5 0.0 3.6e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGF84486.1 - 6.8e-07 28.8 0.0 0.00015 21.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGF84486.1 - 0.00012 21.8 0.0 0.042 13.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGF84486.1 - 0.00013 21.2 0.1 0.00022 20.5 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat EF-hand_6 PF13405.6 EGF84486.1 - 0.00031 20.4 0.0 0.008 16.0 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain TPR_11 PF13414.6 EGF84486.1 - 0.0004 20.0 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 EGF84486.1 - 0.00043 20.4 2.9 0.0081 16.3 0.3 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGF84486.1 - 0.001 19.3 1.6 3.4 8.0 0.0 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat EF-hand_1 PF00036.32 EGF84486.1 - 0.001 18.4 0.1 0.016 14.7 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGF84486.1 - 0.0038 17.6 0.0 0.0095 16.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair TPR_6 PF13174.6 EGF84486.1 - 0.019 15.5 0.1 8 7.3 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat EF-hand_8 PF13833.6 EGF84486.1 - 0.045 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ANAPC3 PF12895.7 EGF84486.1 - 0.05 13.8 0.3 0.64 10.3 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EGF84486.1 - 0.12 13.1 0.1 2.8 8.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 EGF84486.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Pkinase PF00069.25 EGF84487.1 - 1.5e-53 181.8 0.0 1.8e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGF84487.1 - 8.6e-37 126.8 0.0 1.1e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGF84487.1 - 0.0039 16.0 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGF84487.1 - 0.095 12.6 0.0 1.8 8.4 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cation_efflux PF01545.21 EGF84490.1 - 5.9e-45 153.5 16.6 7.3e-45 153.1 16.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1771 PF08590.10 EGF84491.1 - 1.8e-12 47.4 2.0 1.8e-12 47.4 2.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.16 EGF84491.1 - 1.4e-11 43.8 1.8 0.0056 16.4 0.0 3.5 3 0 0 3 3 3 3 CUE domain Smr PF01713.21 EGF84491.1 - 1e-06 29.0 0.0 6.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Smr domain DMA PF03474.14 EGF84491.1 - 6e-05 22.6 0.0 4.4 7.0 0.0 3.4 3 0 0 3 3 3 2 DMRTA motif DUF1296 PF06972.11 EGF84491.1 - 0.0021 18.2 0.1 0.37 11.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) UBA PF00627.31 EGF84491.1 - 0.0073 16.2 0.1 0.48 10.4 0.1 3.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 EGF84491.1 - 0.012 15.5 4.8 1.8 8.4 0.2 4.8 6 0 0 6 6 6 0 UBA-like domain HTH_8 PF02954.19 EGF84491.1 - 0.019 14.7 0.7 16 5.3 0.0 3.5 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family Clc-like PF07062.12 EGF84491.1 - 0.16 11.4 0.2 0.3 10.5 0.2 1.4 1 0 0 1 1 1 0 Clc-like Pinin_SDK_memA PF04696.13 EGF84492.1 - 9.9e-27 93.6 8.6 9.9e-27 93.6 8.6 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Asp PF00026.23 EGF84493.1 - 4e-05 23.2 0.5 0.00014 21.4 0.5 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGF84493.1 - 0.00018 21.3 0.0 0.00053 19.8 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SNF5 PF04855.12 EGF84494.1 - 1.5e-59 201.7 0.3 1.5e-59 201.7 0.3 2.6 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 XLF PF09302.11 EGF84494.1 - 0.00081 19.6 0.0 0.00081 19.6 0.0 3.1 2 1 1 3 3 3 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component TFIIA PF03153.13 EGF84494.1 - 0.21 11.6 20.6 0.011 15.8 15.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Adenylsucc_synt PF00709.21 EGF84495.1 - 4.4e-179 595.8 0.0 5.1e-179 595.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribonuclease_3 PF00636.26 EGF84499.1 - 3.7e-19 69.3 0.1 1.3e-18 67.6 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGF84499.1 - 2.8e-11 43.7 0.0 5.2e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like DUF4600 PF15372.6 EGF84500.1 - 0.0092 16.4 2.4 0.12 12.8 2.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4600) Sporozoite_P67 PF05642.11 EGF84500.1 - 0.016 13.3 7.5 0.087 10.9 0.2 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen S-antigen PF05756.11 EGF84500.1 - 0.15 12.5 1.2 0.36 11.2 1.2 1.7 1 0 0 1 1 1 0 S-antigen protein Presenilin PF01080.17 EGF84500.1 - 0.18 10.5 5.7 0.054 12.3 2.1 1.7 2 0 0 2 2 2 0 Presenilin # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Batrachochytrium_dendrobatidis_JAM81-v1.0/GCA_000203795.1_v1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Batrachochytrium_dendrobatidis_JAM81-v1.0/GCA_000203795.1_v1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Batrachochytrium_dendrobatidis_JAM81-v1.0/GCA_000203795.1_v1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Batrachochytrium_dendrobatidis_JAM81-v1.0/GCA_000203795.1_v1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 17:22:07 2019 # [ok]