# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UQ_con PF00179.21 EAQ82853.1 - 1.1e-34 118.8 0.0 1.2e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ82853.1 - 0.0019 17.9 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B TPR_1 PF00515.23 EAQ82854.1 - 0.028 14.0 0.3 0.062 12.9 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ82854.1 - 0.083 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ82854.1 - 0.13 12.2 0.3 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3597 PF12200.3 EAQ82855.1 - 0.089 13.1 1.9 0.089 13.1 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF3484 PF11983.3 EAQ82855.1 - 0.12 13.2 2.7 0.15 12.9 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) RVT_2 PF07727.9 EAQ82858.1 - 4.3e-13 48.8 0.0 7.4e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ82858.1 - 7.4e-09 35.7 0.0 2.3e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ82858.1 - 1.2e-05 24.8 0.4 3.1e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 EAQ82860.1 - 3.2e-20 72.4 0.0 7.6e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ82860.1 - 3.6e-09 36.1 2.4 9e-09 34.8 1.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EAQ82860.1 - 9.2e-08 32.2 0.1 3.3e-07 30.4 0.0 2.0 2 0 0 2 2 1 1 Integrase core domain Asp_protease_2 PF13650.1 EAQ82860.1 - 4.6e-05 23.8 0.1 9.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease AAA_13 PF13166.1 EAQ82860.1 - 0.00028 19.4 1.8 0.00069 18.2 1.3 1.6 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 EAQ82860.1 - 0.00029 20.4 0.8 0.00072 19.2 0.6 1.6 1 0 0 1 1 1 1 IncA protein ATG16 PF08614.6 EAQ82860.1 - 0.00033 20.5 9.5 0.0007 19.4 6.6 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EAQ82860.1 - 0.015 15.1 4.7 0.081 12.7 1.1 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IN_DBD_C PF00552.16 EAQ82860.1 - 0.025 13.9 2.2 0.09 12.2 0.2 2.5 2 0 0 2 2 2 0 Integrase DNA binding domain BRE1 PF08647.6 EAQ82860.1 - 0.045 13.7 2.5 0.11 12.5 1.8 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase U3_assoc_6 PF08640.6 EAQ82860.1 - 0.071 12.8 0.5 0.19 11.5 0.4 1.7 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Reo_sigmaC PF04582.7 EAQ82860.1 - 0.073 12.2 0.7 0.14 11.3 0.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Uds1 PF15456.1 EAQ82860.1 - 0.19 11.7 6.2 11 6.0 0.3 3.6 2 1 1 3 3 3 0 Up-regulated During Septation DivIC PF04977.10 EAQ82860.1 - 0.21 11.1 0.7 0.64 9.5 0.1 2.1 1 1 1 2 2 2 0 Septum formation initiator WEMBL PF05701.6 EAQ82860.1 - 0.22 9.9 4.4 0.35 9.2 3.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF869 PF05911.6 EAQ82860.1 - 0.24 9.5 1.3 0.37 8.9 0.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Retrotrans_gag PF03732.12 EAQ82860.1 - 0.85 9.7 7.9 0.081 12.9 0.1 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein DUF2450 PF10475.4 EAQ82860.1 - 1.4 7.7 5.8 0.46 9.3 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) SlyX PF04102.7 EAQ82860.1 - 1.7 9.1 12.1 0.34 11.3 0.3 3.1 2 1 1 3 3 2 0 SlyX RVT_1 PF00078.22 EAQ82861.1 - 7.6e-11 41.7 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EAQ82862.1 - 2.3e-32 112.0 0.0 5.1e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IncA PF04156.9 EAQ82862.1 - 0.025 14.1 1.6 0.059 12.9 1.1 1.6 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EAQ82862.1 - 0.07 12.1 2.6 0.15 11.1 1.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 EAQ82862.1 - 0.088 12.6 1.0 0.3 10.9 0.7 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.7 EAQ82862.1 - 0.1 10.7 3.9 0.12 10.4 1.4 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CASP_C PF08172.7 EAQ82862.1 - 0.35 9.8 6.7 0.41 9.6 3.2 2.1 2 0 0 2 2 2 0 CASP C terminal SlyX PF04102.7 EAQ82862.1 - 0.37 11.1 9.0 0.64 10.4 5.3 2.2 1 1 1 2 2 2 0 SlyX ADIP PF11559.3 EAQ82862.1 - 3.9 7.3 12.4 0.21 11.5 4.4 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.8 EAQ82862.1 - 8.9 6.7 13.8 0.58 10.5 0.6 4.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) zf-CCHC PF00098.18 EAQ82862.1 - 9 6.4 12.7 0.023 14.5 1.9 2.0 2 0 0 2 2 2 0 Zinc knuckle CZB PF13682.1 EAQ82863.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain RVT_1 PF00078.22 EAQ82871.1 - 4.6e-32 111.1 0.0 9.3e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ82871.1 - 6.1e-22 77.4 0.0 7.6e-21 73.9 0.0 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ82871.1 - 9e-09 35.6 0.1 1.8e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ82871.1 - 0.0066 16.8 4.1 0.077 13.3 0.7 2.9 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ82871.1 - 0.06 12.3 1.9 0.13 11.2 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mnd1 PF03962.10 EAQ82871.1 - 0.25 10.9 1.4 0.62 9.6 1.0 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4226 PF10774.4 EAQ82871.1 - 0.36 10.8 5.9 0.12 12.4 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) RVT_1 PF00078.22 EAQ82872.1 - 4.7e-06 26.0 0.0 9.7e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPV_P10 PF05531.7 EAQ82872.1 - 0.2 11.9 10.4 2.4 8.4 0.0 5.2 3 3 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.6 EAQ82872.1 - 0.2 10.1 8.5 0.14 10.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Atg14 PF10186.4 EAQ82872.1 - 0.24 10.3 9.9 2 7.3 2.9 2.7 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EAQ82872.1 - 0.24 9.7 7.4 1.4 7.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain Tropomyosin_1 PF12718.2 EAQ82872.1 - 0.82 9.5 6.3 0.19 11.5 0.3 2.9 3 1 1 4 4 4 0 Tropomyosin like CHASE3 PF05227.8 EAQ82872.1 - 2.4 7.8 12.1 0.6 9.7 4.8 2.6 2 0 0 2 2 2 0 CHASE3 domain Abhydrolase_6 PF12697.2 EAQ82873.1 - 2.2e-21 76.7 7.3 2.7e-21 76.5 5.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ82873.1 - 1.5e-10 40.9 0.1 3.8e-10 39.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ82873.1 - 1.9e-09 37.4 0.1 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EAQ82873.1 - 0.018 14.4 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MMPL PF03176.10 EAQ82874.1 - 0.13 10.9 2.5 0.87 8.2 0.1 2.2 2 0 0 2 2 2 0 MMPL family p450 PF00067.17 EAQ82875.1 - 7.2e-21 74.2 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EAQ82876.1 - 1.8e-08 33.9 0.0 7.6e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.11 EAQ82877.1 - 2.5e-26 92.2 31.4 2.5e-26 92.2 21.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1705 PF08019.7 EAQ82877.1 - 0.12 11.8 1.7 8.9 5.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1705) CTP_synth_N PF06418.9 EAQ82878.1 - 5e-96 321.0 0.1 7.7e-96 320.3 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus Tannase PF07519.6 EAQ82878.1 - 1.3e-86 291.2 0.4 1.8e-86 290.7 0.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase GATase PF00117.23 EAQ82878.1 - 3.2e-50 170.2 0.0 4.8e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAQ82878.1 - 0.00018 21.0 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.11 EAQ82879.1 - 1.4e-38 132.5 65.3 2.4e-37 128.4 42.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ82879.1 - 8.7e-10 37.4 19.9 1.5e-09 36.6 13.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SHP PF03579.8 EAQ82879.1 - 0.22 10.9 4.5 4.8 6.6 0.5 3.4 3 0 0 3 3 3 0 Small hydrophobic protein ESSS PF10183.4 EAQ82879.1 - 2.3 8.6 5.3 39 4.7 0.3 3.4 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RmlD_sub_bind PF04321.12 EAQ82880.1 - 0.0086 14.9 1.0 0.024 13.5 0.3 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 EAQ82880.1 - 0.019 14.4 0.5 0.16 11.3 0.4 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAQ82881.1 - 3.6e-07 30.2 0.1 6.6e-07 29.3 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EAQ82881.1 - 0.0021 17.5 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ82881.1 - 0.0024 17.8 0.1 0.0054 16.7 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding HET PF06985.6 EAQ82882.1 - 1.6e-24 86.6 0.0 3.8e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EAQ82883.1 - 1.1e-59 202.2 0.0 2.2e-40 138.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 NDUF_B8 PF05821.6 EAQ82884.1 - 0.00039 20.1 1.0 0.00076 19.1 0.5 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EAQ82885.1 - 1.9e-73 246.9 0.4 1.9e-73 246.9 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ82885.1 - 3.6e-14 52.3 0.0 8.4e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ82885.1 - 8e-08 32.3 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.8 EAQ82885.1 - 4.6e-05 23.1 4.1 0.00017 21.3 2.9 2.0 1 0 0 1 1 1 1 HSA DEAD PF00270.24 EAQ82885.1 - 6.6e-05 22.4 0.0 0.00018 21.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EAQ82885.1 - 0.0015 17.4 1.1 0.17 10.6 0.0 2.8 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 EAQ82885.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 FixQ PF05545.6 EAQ82886.1 - 2.2 7.9 6.0 1.5 8.4 0.2 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ NAD_binding_10 PF13460.1 EAQ82888.1 - 2.6e-10 40.5 0.2 4.4e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ82888.1 - 4.4e-09 35.9 0.0 5.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EAQ82888.1 - 1.5e-06 27.4 0.0 3.6e-06 26.2 0.0 1.6 1 1 1 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 EAQ82888.1 - 0.0048 16.3 0.1 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAQ82888.1 - 0.0085 16.0 0.2 0.019 14.8 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EAQ82888.1 - 0.021 15.1 0.1 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ82888.1 - 0.026 14.9 0.2 0.055 13.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EAQ82888.1 - 0.067 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EAQ82888.1 - 0.075 12.6 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 KR domain GMC_oxred_N PF00732.14 EAQ82889.1 - 3e-29 102.1 0.0 1.8e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ82889.1 - 7.5e-29 100.8 0.0 2.2e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAQ82889.1 - 0.00041 19.3 0.1 0.037 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EAQ82889.1 - 0.00098 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ82889.1 - 0.0079 15.1 0.2 0.4 9.5 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ82889.1 - 0.034 14.1 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ82889.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EAQ82889.1 - 0.087 11.6 0.0 0.68 8.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EAQ82889.1 - 0.11 12.4 0.0 37 4.2 0.0 3.2 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ82889.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Fructosamin_kin PF03881.9 EAQ82890.1 - 1.2e-32 113.0 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAQ82890.1 - 5.1e-06 26.3 0.0 7.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 EAQ82891.1 - 9.8e-18 64.8 1.4 1.3e-17 64.4 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ82891.1 - 7.3e-05 22.4 0.0 9.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EAQ82891.1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EAQ82891.1 - 0.004 16.9 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2101 PF09874.4 EAQ82893.1 - 0.0097 15.4 2.3 0.024 14.1 1.6 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2101) Myotoxins PF00819.12 EAQ82895.1 - 0.038 14.0 0.1 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Myotoxin MscS_TM PF12794.2 EAQ82896.1 - 0.22 10.0 2.1 0.34 9.4 1.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Gag_spuma PF03276.9 EAQ82896.1 - 3.2 5.9 10.6 4.8 5.3 7.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF86 PF01934.12 EAQ82898.1 - 0.037 13.6 0.1 0.06 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 DEC-1_N PF04625.8 EAQ82898.1 - 0.3 9.7 24.0 0.42 9.2 16.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CRAL_TRIO PF00650.15 EAQ82902.1 - 9.9e-15 54.3 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAQ82902.1 - 0.0011 19.0 0.2 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Podoplanin PF05808.6 EAQ82903.1 - 0.033 13.7 2.5 0.047 13.2 1.7 1.2 1 0 0 1 1 1 0 Podoplanin Rax2 PF12768.2 EAQ82903.1 - 0.19 10.9 0.9 0.27 10.3 0.6 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Gly-zipper_OmpA PF13436.1 EAQ82903.1 - 1.9 8.1 7.2 3.1 7.4 5.0 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Asp PF00026.18 EAQ82904.1 - 1.8e-21 76.6 0.0 1.9e-19 70.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ82904.1 - 7e-07 29.3 0.2 4.4e-06 26.7 0.2 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ82904.1 - 0.00089 19.7 0.2 0.045 14.2 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease YadA_stalk PF05662.9 EAQ82904.1 - 0.13 12.0 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin RVT_2 PF07727.9 EAQ82905.1 - 7.8e-60 201.8 0.0 1.3e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ82905.1 - 4.4e-17 62.3 0.0 1.2e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ82905.1 - 0.019 14.5 0.1 0.048 13.3 0.1 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain RVP PF00077.15 EAQ82905.1 - 0.044 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease UBN2 PF14223.1 EAQ82905.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_AsnC-type PF13404.1 EAQ82905.1 - 0.15 11.6 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cu-oxidase_3 PF07732.10 EAQ82906.1 - 7.5e-44 148.2 0.6 6.7e-43 145.1 0.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EAQ82906.1 - 1.5e-33 115.9 0.0 3.3e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ82906.1 - 3.2e-26 91.4 3.0 5.2e-21 74.5 0.0 4.0 3 1 0 3 3 3 2 Multicopper oxidase DUF3505 PF12013.3 EAQ82907.1 - 6.7e-06 26.3 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) FAR1 PF03101.10 EAQ82907.1 - 0.0037 17.7 0.0 0.0096 16.4 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain TPR_10 PF13374.1 EAQ82908.1 - 8e-185 594.4 0.2 1.1e-13 50.5 0.0 13.7 13 0 0 13 13 13 13 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ82908.1 - 8.6e-157 509.4 0.0 5.8e-17 61.4 0.0 9.1 1 1 9 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ82908.1 - 3.5e-54 176.3 7.0 0.00085 18.9 0.0 13.1 13 0 0 13 13 13 12 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ82908.1 - 2.7e-34 114.4 1.7 0.61 10.4 0.0 12.7 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ82908.1 - 8.3e-24 82.1 0.1 5.6 6.7 0.0 12.8 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ82908.1 - 4.3e-22 76.2 5.2 3 7.9 0.0 13.3 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ82908.1 - 8.4e-21 74.1 0.0 0.13 13.0 0.0 10.5 4 2 7 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ82908.1 - 1.6e-20 72.4 0.4 0.038 13.6 0.0 8.4 3 2 4 9 9 9 5 TPR repeat TPR_4 PF07721.9 EAQ82908.1 - 2.7e-20 70.6 0.0 9.8 6.9 0.0 13.5 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ82908.1 - 1.1e-17 64.0 0.0 0.31 11.4 0.0 11.3 4 2 7 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ82908.1 - 2.6e-13 48.7 9.2 12 5.9 0.0 11.9 12 0 0 12 12 12 0 Tetratricopeptide repeat Apc3 PF12895.2 EAQ82908.1 - 2.8e-12 46.6 0.0 0.26 11.4 0.0 7.7 1 1 8 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 PNP_UDP_1 PF01048.15 EAQ82908.1 - 1.9e-11 43.4 0.8 7.3e-11 41.4 0.6 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_14 PF13428.1 EAQ82908.1 - 2.4e-11 43.2 3.5 39 5.2 0.0 12.2 12 1 1 13 13 12 0 Tetratricopeptide repeat DUF2664 PF10867.3 EAQ82908.1 - 1.7e-10 41.3 7.5 41 4.8 0.0 11.4 11 1 1 12 12 12 0 Protein of unknown function (DUF2664) PPR PF01535.15 EAQ82908.1 - 1.3e-09 37.3 2.9 84 3.4 0.0 11.1 13 0 0 13 13 12 0 PPR repeat TPR_5 PF12688.2 EAQ82908.1 - 2.9e-07 30.5 5.8 0.68 9.9 0.0 6.6 3 2 5 8 8 8 2 Tetratrico peptide repeat Rab5-bind PF09311.6 EAQ82908.1 - 1.3e-06 28.4 24.1 6.6 6.5 0.3 10.0 1 1 10 11 11 11 1 Rabaptin-like protein DUF832 PF05734.6 EAQ82908.1 - 3.3e-05 23.1 3.2 9.2 5.4 0.0 5.7 1 1 10 11 11 11 0 Herpesvirus protein of unknown function (DUF832) TPR_6 PF13174.1 EAQ82908.1 - 0.006 16.9 17.4 31 5.3 0.0 10.1 12 0 0 12 12 11 0 Tetratricopeptide repeat RVT_1 PF00078.22 EAQ82908.1 - 0.012 15.0 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Trans_reg_C PF00486.23 EAQ82908.1 - 2.7 7.9 7.5 11 6.0 0.0 5.5 3 2 4 8 8 8 0 Transcriptional regulatory protein, C terminal PIF1 PF05970.9 EAQ82911.1 - 2e-06 27.0 0.8 0.0002 20.4 0.1 2.8 1 1 2 3 3 3 2 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ82911.1 - 0.0004 18.2 0.0 0.00067 17.5 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ82911.1 - 0.00048 20.2 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Helitron_like_N PF14214.1 EAQ82912.1 - 2.1e-23 83.0 0.4 3.5e-23 82.2 0.3 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MULE PF10551.4 EAQ82913.1 - 1e-18 67.2 0.0 2.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ82913.1 - 0.0009 17.8 0.0 0.0009 17.8 0.0 1.8 2 0 0 2 2 2 1 Transposase, Mutator family His_Phos_1 PF00300.17 EAQ82914.1 - 4.8e-11 42.9 0.0 7.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Hce2 PF14856.1 EAQ82915.1 - 1.8e-17 62.9 0.8 2.9e-17 62.3 0.5 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor MFS_1 PF07690.11 EAQ82916.1 - 6.1e-24 84.3 48.9 1.2e-23 83.4 33.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily GCR1_C PF12550.3 EAQ82916.1 - 1.6e-20 72.7 1.1 3.6e-20 71.6 0.7 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MFS_2 PF13347.1 EAQ82916.1 - 0.00036 19.0 13.9 0.00036 19.0 9.6 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein TPR_11 PF13414.1 EAQ82917.1 - 1e-13 50.6 1.8 0.00013 21.5 0.0 4.6 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EAQ82917.1 - 2.5e-10 39.4 11.6 0.001 18.8 0.0 6.5 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ82917.1 - 1.1e-09 37.4 2.0 0.0063 16.0 0.0 5.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ82917.1 - 5.9e-07 30.0 7.7 0.25 12.0 0.3 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ82917.1 - 9.6e-07 29.0 0.1 0.0046 17.2 0.1 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ82917.1 - 1.4e-06 28.1 1.7 0.012 15.5 0.0 4.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ82917.1 - 0.0002 21.7 12.6 27 5.7 0.1 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ82917.1 - 0.0009 19.2 0.2 29 5.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ82917.1 - 0.0016 18.1 0.1 18 5.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EAQ82917.1 - 0.03 14.4 0.0 0.41 10.8 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EAQ82917.1 - 0.041 13.7 6.3 0.074 12.8 0.1 4.1 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ82917.1 - 0.061 13.7 14.8 1.3 9.6 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ82917.1 - 0.23 11.3 2.5 22 4.9 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ82917.1 - 5.6 7.0 8.4 5.7 7.0 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NMO PF03060.10 EAQ82918.1 - 1.1e-38 133.2 0.5 1.4e-38 132.9 0.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EAQ82918.1 - 1.4e-07 30.7 0.9 2e-07 30.1 0.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EAQ82918.1 - 1.2e-05 24.4 0.7 2e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EAQ82918.1 - 0.0001 21.3 0.4 0.00019 20.4 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EAQ82918.1 - 0.0017 17.3 0.2 0.0028 16.6 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fungal_trans PF04082.13 EAQ82919.1 - 2.9e-08 32.9 0.1 4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_1 PF03184.14 EAQ82921.1 - 9.2e-50 168.7 0.0 1.4e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ82921.1 - 1.1e-06 28.5 0.0 2.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ82921.1 - 0.014 14.9 0.1 0.062 12.8 0.0 2.1 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DUF2750 PF11042.3 EAQ82921.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) zf-CCHC PF00098.18 EAQ82921.1 - 0.14 12.1 4.7 0.27 11.2 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Prominin PF05478.6 EAQ82921.1 - 0.22 8.9 0.5 0.35 8.3 0.4 1.1 1 0 0 1 1 1 0 Prominin RVT_1 PF00078.22 EAQ82922.1 - 1.9e-24 86.2 0.0 3.9e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ82922.1 - 9.8e-14 50.9 0.1 3.1e-12 46.1 0.1 3.2 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase SlyX PF04102.7 EAQ82922.1 - 0.0055 17.0 4.0 0.088 13.1 1.4 2.7 1 1 1 2 2 2 2 SlyX zf-CCHC PF00098.18 EAQ82922.1 - 0.013 15.4 2.4 0.013 15.4 1.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Phage_lysis PF03245.8 EAQ82922.1 - 0.059 13.3 4.3 0.13 12.2 0.4 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein adh_short PF00106.20 EAQ82923.1 - 1.8e-12 47.4 0.0 1.8e-12 47.4 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Fungal_trans PF04082.13 EAQ82923.1 - 3.7e-07 29.2 0.2 7.9e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain KR PF08659.5 EAQ82923.1 - 5.8e-05 22.8 0.7 0.00021 21.0 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EAQ82923.1 - 0.0066 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ82923.1 - 0.016 14.6 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAQ82923.1 - 0.044 13.5 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GMC_oxred_N PF00732.14 EAQ82924.1 - 2e-36 125.6 0.1 2e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ82924.1 - 4.4e-31 108.1 0.0 7.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ82924.1 - 1e-07 31.2 0.1 3.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ82924.1 - 4.8e-06 26.4 0.1 2e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ82924.1 - 4.5e-05 22.4 0.1 0.049 12.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EAQ82924.1 - 0.0029 17.7 0.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ82924.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EAQ82924.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EAQ82924.1 - 0.033 14.1 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 EAQ82924.1 - 0.055 13.3 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ82924.1 - 0.069 12.0 0.0 4.7 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EAQ82924.1 - 0.082 11.3 0.0 0.25 9.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EAQ82924.1 - 0.1 13.0 0.1 0.1 13.0 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ82924.1 - 0.13 11.3 0.1 0.3 10.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EAQ82925.1 - 3.4e-16 59.7 0.0 4.6e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ82925.1 - 4.4e-06 26.9 0.5 0.00033 20.7 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ82925.1 - 2e-05 23.7 0.1 5.1e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EAQ82925.1 - 2.4e-05 23.4 0.0 0.063 12.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EAQ82925.1 - 5.3e-05 21.8 0.1 0.0024 16.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EAQ82925.1 - 8.2e-05 21.6 1.3 0.00012 21.0 0.2 1.8 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EAQ82925.1 - 0.0002 20.3 0.7 0.013 14.3 0.1 2.3 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EAQ82925.1 - 0.00043 20.1 1.8 0.28 10.9 0.3 2.5 1 1 1 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAQ82925.1 - 0.0013 18.6 0.1 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EAQ82925.1 - 0.0027 16.7 0.1 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EAQ82925.1 - 0.015 14.3 0.7 0.2 10.7 0.1 2.3 2 1 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 EAQ82925.1 - 0.12 11.3 2.1 0.18 10.8 0.8 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAQ82925.1 - 0.13 11.1 1.1 0.3 9.9 0.3 1.8 1 1 0 2 2 2 0 Lycopene cyclase protein AMP-binding PF00501.23 EAQ82926.1 - 4.6e-43 147.1 0.7 1e-26 93.3 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Zn_clus PF00172.13 EAQ82927.1 - 0.0011 18.8 6.5 0.0011 18.8 4.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EAQ82927.1 - 0.057 12.4 0.5 0.39 9.6 0.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Suf PF05843.9 EAQ82927.1 - 1.2 8.8 12.9 0.5 10.0 7.2 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 EAQ82927.1 - 1.2 8.9 5.4 2.5 7.9 3.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 p450 PF00067.17 EAQ82928.1 - 6.6e-66 222.7 0.0 8.3e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CMD PF02627.15 EAQ82930.1 - 5.5e-05 22.9 0.2 0.0028 17.4 0.0 2.6 3 1 0 3 3 3 2 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 EAQ82931.1 - 4.5e-33 114.4 65.3 4.9e-25 88.0 30.9 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ82931.1 - 6.8e-10 38.1 7.8 6.8e-10 38.1 5.4 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF4538 PF15061.1 EAQ82931.1 - 4.3 6.7 5.3 2.2 7.6 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) ADH_zinc_N PF00107.21 EAQ82932.1 - 3.8e-06 26.4 0.1 1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Peripla_BP_4 PF13407.1 EAQ82932.1 - 0.046 13.0 0.8 0.081 12.2 0.5 1.5 1 1 0 1 1 1 0 Periplasmic binding protein domain Methyltransf_3 PF01596.12 EAQ82933.1 - 4.2e-31 107.5 0.0 5.2e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EAQ82933.1 - 3.2e-16 60.0 0.0 6.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ82933.1 - 7.8e-14 52.2 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ82933.1 - 9e-13 48.0 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ82933.1 - 1.3e-05 25.1 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ82933.1 - 1.8e-05 25.1 0.0 6.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EAQ82933.1 - 4e-05 23.2 0.0 5.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EAQ82933.1 - 7.5e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAQ82933.1 - 0.0002 20.7 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 EAQ82933.1 - 0.0056 15.8 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EAQ82933.1 - 0.0056 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EAQ82933.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EAQ82933.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 EAQ82933.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EAQ82933.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CmcI PF04989.7 EAQ82933.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase AMP-binding PF00501.23 EAQ82934.1 - 6.4e-172 571.6 0.1 1.3e-90 303.8 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EAQ82934.1 - 8e-67 225.2 0.1 8.9e-32 110.1 0.0 4.5 4 1 0 4 4 4 4 Condensation domain AMP-binding_C PF13193.1 EAQ82934.1 - 6.5e-17 62.2 0.2 3.2e-09 37.6 0.0 3.3 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EAQ82934.1 - 9e-15 54.6 0.0 5e-07 29.8 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Adap_comp_sub PF00928.16 EAQ82935.1 - 1.1e-70 237.8 0.0 1.1e-63 214.7 0.0 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAQ82935.1 - 5.9e-05 22.8 0.2 0.0001 22.0 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EAQ82935.1 - 0.028 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Packaging_FI PF14000.1 EAQ82936.1 - 0.042 14.0 0.8 0.1 12.7 0.6 1.6 1 0 0 1 1 1 0 DNA packaging protein FI DUF607 PF04678.8 EAQ82936.1 - 0.17 11.7 0.9 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF607 IncA PF04156.9 EAQ82936.1 - 0.22 11.0 6.3 0.66 9.5 0.0 2.4 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EAQ82936.1 - 1.4 9.4 6.8 0.35 11.3 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Vma12 PF11712.3 EAQ82936.1 - 8.9 6.0 6.9 34 4.1 4.3 2.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Bestrophin PF01062.16 EAQ82937.1 - 7.2e-44 149.8 0.4 1.5e-24 86.4 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF3040 PF11239.3 EAQ82937.1 - 0.33 11.0 2.4 1 9.4 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MFS_1 PF07690.11 EAQ82938.1 - 3.1e-28 98.5 21.4 5e-28 97.8 14.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Patatin PF01734.17 EAQ82939.1 - 2.2e-21 76.7 0.1 4.2e-20 72.5 0.1 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2075 PF09848.4 EAQ82939.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EAQ82939.1 - 0.038 13.9 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAQ82939.1 - 0.041 13.5 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EAQ82939.1 - 0.057 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EAQ82939.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EAQ82939.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.22 EAQ82940.1 - 5.9e-23 81.3 0.0 2.9e-17 62.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PLDc_2 PF13091.1 EAQ82942.1 - 6.2e-19 67.9 0.0 5.4e-11 42.3 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EAQ82942.1 - 0.00036 20.2 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif ThuA PF06283.6 EAQ82943.1 - 2.7e-67 226.6 0.0 3.2e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.1 EAQ82943.1 - 0.0049 16.0 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) DUF1355 PF07090.6 EAQ82943.1 - 0.1 11.9 0.1 0.39 10.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1355) Glyco_hydro_6 PF01341.12 EAQ82944.1 - 4e-104 348.2 0.8 5.1e-104 347.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EAQ82944.1 - 3.1e-14 52.3 16.1 9.2e-14 50.8 11.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain MSP1_C PF07462.6 EAQ82944.1 - 3.1 6.0 3.5 4.4 5.5 2.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Opi1 PF08618.5 EAQ82945.1 - 2.6e-67 227.6 1.4 9.8e-43 146.6 0.3 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 DDE_1 PF03184.14 EAQ82946.1 - 9.7e-38 129.4 0.2 1.5e-37 128.8 0.0 1.3 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ82946.1 - 4.1e-05 23.3 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EAQ82946.1 - 0.043 13.9 0.1 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF4470 PF14737.1 EAQ82947.1 - 5.1e-20 71.0 0.0 9e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EAQ82947.1 - 7.2e-19 67.1 1.0 7.1e-14 51.2 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAQ82947.1 - 7.1e-11 41.1 1.6 0.0003 20.4 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ82947.1 - 2.3e-08 33.8 2.1 0.00019 21.3 0.2 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ82947.1 - 3.1e-06 27.4 1.3 0.0017 18.6 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ82947.1 - 3.1e-05 23.4 1.7 0.027 14.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ82947.1 - 4.1e-05 23.0 1.0 0.0039 16.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ82947.1 - 4.2e-05 22.9 3.1 0.078 12.6 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ82947.1 - 0.00073 20.1 5.0 0.002 18.7 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ82947.1 - 0.00095 19.1 0.0 0.014 15.5 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ82947.1 - 0.021 14.9 0.2 0.1 12.7 0.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EAQ82947.1 - 0.1 12.7 0.1 0.58 10.3 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ82947.1 - 0.13 12.9 8.5 11 6.9 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ82947.1 - 0.17 12.4 0.7 59 4.4 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Adap_comp_sub PF00928.16 EAQ82948.1 - 3.4e-90 301.7 0.0 4.4e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAQ82948.1 - 1e-06 28.4 3.2 3.5e-06 26.7 2.2 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain HeLo PF14479.1 EAQ82951.1 - 1.9e-64 217.2 0.8 3.1e-64 216.6 0.5 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 EAQ82951.1 - 0.00061 19.0 0.0 0.00098 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ82951.1 - 0.0013 17.8 0.0 0.0031 16.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2100 PF09873.4 EAQ82951.1 - 0.09 12.2 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Pkinase PF00069.20 EAQ82952.1 - 7e-33 113.8 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ82952.1 - 1.8e-25 89.5 0.0 2.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.25 EAQ82952.1 - 7.9e-11 41.2 0.2 0.00017 21.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EAQ82952.1 - 2.5e-10 40.5 0.0 7.1e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ82952.1 - 1e-08 35.4 1.1 0.00011 22.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ82952.1 - 5.2e-07 29.2 0.2 0.00081 19.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EAQ82952.1 - 5.9e-06 26.3 2.4 0.00019 21.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 EAQ82952.1 - 0.096 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF3574 PF12098.3 EAQ82953.1 - 0.019 14.5 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) PAN_4 PF14295.1 EAQ82954.1 - 0.003 17.2 0.3 0.02 14.5 0.2 2.4 1 1 0 1 1 1 1 PAN domain Abhydrolase_3 PF07859.8 EAQ82955.1 - 5.8e-17 61.9 0.0 4.9e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ82955.1 - 8.5e-08 31.6 0.0 0.00036 19.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAQ82955.1 - 5.6e-07 29.6 0.6 9e-07 28.9 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ82955.1 - 8.2e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family CBM_1 PF00734.13 EAQ82956.1 - 1e-10 41.0 13.3 1e-10 41.0 9.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 EAQ82956.1 - 0.0026 16.3 0.0 0.0047 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Aminotran_5 PF00266.14 EAQ82957.1 - 0.00026 19.8 0.1 0.0044 15.8 0.1 2.0 2 0 0 2 2 2 2 Aminotransferase class-V RVT_1 PF00078.22 EAQ82958.1 - 2.7e-41 141.2 0.0 2e-39 135.1 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ82958.1 - 2.1e-14 53.1 0.0 1.2e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ82958.1 - 1.2e-09 38.4 0.0 2.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thymidylate_kin PF02223.12 EAQ82960.1 - 6.3e-40 136.5 0.0 1.9e-38 131.7 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EAQ82960.1 - 0.00011 22.2 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EAQ82960.1 - 0.0016 17.7 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 GTP_cyclohydroI PF01227.17 EAQ82961.1 - 2.8e-57 192.8 2.5 3.1e-57 192.7 1.8 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EAQ82961.1 - 0.0002 21.2 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.12 EAQ82961.1 - 0.017 14.1 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TAFII28 PF04719.9 EAQ82962.1 - 8.3e-22 76.7 2.1 1.5e-11 43.9 0.1 3.3 3 0 0 3 3 3 3 hTAFII28-like protein conserved region Ribosomal_L27 PF01016.14 EAQ82964.1 - 5.3e-23 80.6 0.8 5.3e-23 80.6 0.5 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein IPP-2 PF04979.9 EAQ82964.1 - 1.2e-05 25.5 0.7 1.2e-05 25.5 0.5 4.1 3 1 1 4 4 4 2 Protein phosphatase inhibitor 2 (IPP-2) Sugar_tr PF00083.19 EAQ82966.1 - 7e-80 268.7 20.8 8.3e-80 268.5 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ82966.1 - 1.8e-18 66.3 24.4 7.8e-13 47.8 4.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ham1p_like PF01725.11 EAQ82966.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ham1 family DUF706 PF05153.10 EAQ82967.1 - 1.8e-123 410.8 0.0 2.2e-123 410.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) UvdE PF03851.9 EAQ82969.1 - 1.9e-118 394.4 0.0 2.5e-118 394.0 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE PARP PF00644.15 EAQ82970.1 - 1.5e-57 194.3 0.0 3.4e-57 193.1 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EAQ82970.1 - 1e-42 144.9 0.3 1.6e-42 144.3 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EAQ82970.1 - 6.9e-23 80.4 0.1 1.9e-22 79.0 0.1 1.8 1 0 0 1 1 1 1 WGR domain Zn_clus PF00172.13 EAQ82970.1 - 6.6e-15 54.7 26.1 1.6e-08 34.3 4.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.21 EAQ82970.1 - 1.3e-12 47.6 0.0 3.1e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Fungal_trans PF04082.13 EAQ82970.1 - 7.7e-12 44.6 0.3 2.9e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PTCB-BRCT PF12738.2 EAQ82970.1 - 7.5e-07 28.9 0.1 1.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain NYD-SP12_N PF15015.1 EAQ82970.1 - 0.074 11.2 0.4 0.11 10.6 0.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal FAD_binding_4 PF01565.18 EAQ82972.1 - 3e-13 49.4 2.6 3e-13 49.4 1.8 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAQ82972.1 - 3.6e-08 33.1 0.1 7e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.6 EAQ82974.1 - 1.4e-31 109.5 0.0 2.4e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNase_H PF00075.19 EAQ82976.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EAQ82977.1 - 0.0022 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FTA2 PF13095.1 EAQ82978.1 - 3.6e-58 196.5 0.0 4.3e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_47 PF01532.15 EAQ82979.1 - 7.7e-145 483.0 0.0 8.9e-145 482.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SRP54 PF00448.17 EAQ82980.1 - 2.5e-75 252.2 0.8 5.3e-75 251.1 0.5 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EAQ82980.1 - 3.8e-26 91.3 4.9 3.8e-26 91.3 3.4 3.8 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 EAQ82980.1 - 1.8e-15 56.7 0.1 5.2e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EAQ82980.1 - 1.4e-08 34.3 0.1 4.2e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EAQ82980.1 - 2.3e-07 30.7 0.1 6e-07 29.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EAQ82980.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EAQ82980.1 - 3.7e-05 24.5 0.0 8.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EAQ82980.1 - 8.1e-05 22.1 0.1 0.00029 20.2 0.1 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EAQ82980.1 - 0.00042 20.2 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 EAQ82980.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EAQ82980.1 - 0.0021 17.2 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EAQ82980.1 - 0.0022 18.1 0.1 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ82980.1 - 0.0029 17.6 0.1 0.0082 16.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 EAQ82980.1 - 0.0056 16.0 0.2 0.02 14.2 0.0 2.0 2 0 0 2 2 2 1 Thymidylate kinase ATP_bind_1 PF03029.12 EAQ82980.1 - 0.0059 16.1 0.2 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EAQ82980.1 - 0.0065 15.2 3.2 0.0077 15.0 0.5 2.3 2 1 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 EAQ82980.1 - 0.0067 16.7 0.0 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EAQ82980.1 - 0.011 14.9 0.5 2.2 7.4 0.6 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit TrwB_AAD_bind PF10412.4 EAQ82980.1 - 0.015 13.9 0.0 0.034 12.7 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EAQ82980.1 - 0.026 14.4 0.1 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EAQ82980.1 - 0.029 13.8 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain 6PF2K PF01591.13 EAQ82980.1 - 0.043 12.8 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.24 EAQ82980.1 - 0.046 13.9 0.2 0.16 12.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EAQ82980.1 - 0.049 13.3 0.0 0.2 11.3 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Arf PF00025.16 EAQ82980.1 - 0.062 12.5 0.1 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family VirE PF05272.6 EAQ82980.1 - 0.082 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.22 EAQ82980.1 - 0.11 12.7 0.6 0.36 11.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter ARGLU PF15346.1 EAQ82981.1 - 0.035 13.8 1.5 0.035 13.8 1.0 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 GSDH PF07995.6 EAQ82982.1 - 9.1e-09 34.8 0.2 2.1e-08 33.6 0.2 1.6 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EAQ82982.1 - 0.035 13.4 0.0 0.11 11.8 0.0 1.9 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 EAQ82982.1 - 0.059 13.0 0.0 0.21 11.2 0.0 2.0 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RVT_1 PF00078.22 EAQ82983.1 - 1.4e-39 135.6 0.0 2.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.16 EAQ82984.1 - 3e-16 59.1 0.0 4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ82984.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain LysM PF01476.15 EAQ82985.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 LysM domain Chitin_bind_1 PF00187.14 EAQ82985.1 - 0.025 14.5 18.6 0.025 14.5 12.9 4.6 4 0 0 4 4 4 0 Chitin recognition protein MFS_1 PF07690.11 EAQ82988.1 - 1e-32 113.2 27.7 1e-32 113.2 19.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily YfhO PF09586.5 EAQ82988.1 - 0.16 9.9 2.0 0.28 9.1 1.4 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SET PF00856.23 EAQ82991.1 - 0.00053 20.3 0.0 0.12 12.7 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_14 PF13428.1 EAQ82991.1 - 0.11 13.2 0.1 1.7 9.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ82991.1 - 0.16 11.9 0.8 0.79 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 EAQ82992.1 - 1.3e-28 99.7 0.0 4.1e-28 98.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 DUF3237 PF11578.3 EAQ82993.1 - 1.5e-42 144.4 0.0 2.6e-42 143.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) F_bP_aldolase PF01116.15 EAQ82994.1 - 3.6e-73 246.1 0.0 7.1e-73 245.2 0.0 1.5 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF829 PF05705.9 EAQ82995.1 - 3.3e-71 239.7 0.0 3.8e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 4HBT_3 PF13622.1 EAQ82996.1 - 2.7e-50 171.5 0.0 3.1e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Hydantoinase_B PF02538.9 EAQ82996.1 - 0.19 9.8 0.0 0.29 9.2 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase p450 PF00067.17 EAQ82998.1 - 9.9e-50 169.3 0.0 1.4e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribonucleas_3_3 PF14622.1 EAQ83000.1 - 9.4e-29 99.9 0.0 1.4e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EAQ83000.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease III domain KAT11 PF08214.6 EAQ83001.1 - 2.2e-27 96.0 0.0 2.6e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein SET PF00856.23 EAQ83002.1 - 1.4e-11 44.9 0.0 1.1e-10 42.0 0.0 2.3 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EAQ83002.1 - 3.3e-07 30.2 0.6 3.3e-07 30.2 0.4 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF2183 PF09949.4 EAQ83003.1 - 6.6e-30 102.9 0.0 3e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) GCR1_C PF12550.3 EAQ83004.1 - 7.3e-22 77.0 0.2 1.4e-21 76.1 0.2 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Exo_endo_phos_2 PF14529.1 EAQ83005.1 - 1.8e-13 50.1 0.0 4.9e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ83005.1 - 2.7e-06 27.5 0.7 0.00015 21.7 0.2 2.3 1 1 1 2 2 2 2 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EAQ83005.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EAQ83007.1 - 8.7e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ83007.1 - 1.3e-05 24.6 0.2 2.8e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_29 PF13551.1 EAQ83008.1 - 8.2e-19 67.8 8.0 9.6e-11 41.8 2.6 2.5 2 0 0 2 2 2 2 Winged helix-turn helix DDE_3 PF13358.1 EAQ83008.1 - 2e-17 63.3 0.7 4.5e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ83008.1 - 2.6e-17 62.6 4.8 2.6e-17 62.6 3.4 2.3 3 0 0 3 3 3 1 Transposase HTH_28 PF13518.1 EAQ83008.1 - 3.6e-11 42.8 2.4 0.00034 20.5 0.0 3.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.1 EAQ83008.1 - 4e-09 35.8 14.6 0.00032 20.2 0.1 4.1 4 0 0 4 4 4 2 Homeodomain-like domain HTH_32 PF13565.1 EAQ83008.1 - 2.7e-06 28.0 2.2 2.7e-06 28.0 1.5 3.0 3 1 0 3 3 2 1 Homeodomain-like domain CENP-B_N PF04218.8 EAQ83008.1 - 4.2e-05 22.8 3.6 0.27 10.6 0.3 4.3 4 0 0 4 4 4 2 CENP-B N-terminal DNA-binding domain PAX PF00292.13 EAQ83008.1 - 0.00061 19.4 1.4 0.041 13.5 0.1 2.3 2 0 0 2 2 2 1 'Paired box' domain HTH_7 PF02796.10 EAQ83008.1 - 0.0011 18.8 0.9 0.22 11.4 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EAQ83008.1 - 0.0023 17.4 7.1 1.3 8.6 0.0 3.8 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 EAQ83008.1 - 0.022 14.4 1.1 4.5 6.9 0.0 2.7 2 1 0 2 2 2 0 Transposase HTH_Tnp_ISL3 PF13542.1 EAQ83008.1 - 0.027 13.6 14.9 0.053 12.6 0.2 4.7 5 0 0 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.1 EAQ83008.1 - 0.03 13.7 1.4 5.4 6.4 0.4 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.1 EAQ83008.1 - 0.1 12.1 5.3 0.64 9.5 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 EAQ83008.1 - 0.11 12.2 0.3 0.11 12.2 0.2 3.0 3 0 0 3 3 3 0 MarR family GntR PF00392.16 EAQ83008.1 - 0.21 11.0 3.2 13 5.3 0.1 3.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Helicase_C PF00271.26 EAQ83009.1 - 4.1e-08 32.9 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HTH_psq PF05225.11 EAQ83010.1 - 2.7e-21 74.8 0.1 5.7e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ83010.1 - 1.2e-17 63.4 0.1 6.3e-13 48.3 0.0 3.2 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EAQ83010.1 - 1.5e-17 63.5 0.3 1.2e-10 40.8 0.0 4.2 4 1 1 5 5 5 3 DDE superfamily endonuclease HTH_23 PF13384.1 EAQ83010.1 - 2.6e-06 26.8 1.3 0.043 13.4 0.0 4.0 4 0 0 4 4 4 2 Homeodomain-like domain HTH_3 PF01381.17 EAQ83010.1 - 0.0082 15.9 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.1 EAQ83010.1 - 0.038 13.8 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.1 EAQ83010.1 - 0.56 10.2 6.2 7.2 6.7 0.0 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain RVT_1 PF00078.22 EAQ83011.1 - 2.4e-09 36.8 0.0 3.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EAQ83012.1 - 1.4e-12 47.2 0.0 1.2e-06 27.7 0.0 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease DHBP_synthase PF00926.14 EAQ83012.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase Pyr_redox_2 PF07992.9 EAQ83014.1 - 2.1e-17 63.6 0.0 3.8e-17 62.8 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ83014.1 - 1.6e-14 54.0 0.4 1.1e-09 38.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ83014.1 - 3.8e-11 42.4 5.6 0.02 13.8 0.0 4.1 4 0 0 4 4 4 4 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ83014.1 - 1.6e-06 28.3 0.4 0.00024 21.2 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ83014.1 - 1.6e-05 24.6 2.8 0.46 10.2 0.1 3.3 2 1 1 3 3 3 3 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAQ83014.1 - 0.00052 19.9 0.1 2 8.5 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Sigma70_ECF PF07638.6 EAQ83014.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor TrkA_N PF02254.13 EAQ83014.1 - 0.16 11.9 1.0 0.88 9.5 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain Lycopene_cycl PF05834.7 EAQ83014.1 - 0.22 10.3 4.5 7.8 5.2 0.1 3.3 3 1 0 4 4 4 0 Lycopene cyclase protein HI0933_like PF03486.9 EAQ83014.1 - 0.57 8.5 3.1 0.55 8.6 0.1 2.4 4 0 0 4 4 4 0 HI0933-like protein Zn_clus PF00172.13 EAQ83015.1 - 5.9e-09 35.6 11.4 1.5e-08 34.4 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ83015.1 - 3.9e-08 32.4 0.0 5.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PALP PF00291.20 EAQ83016.1 - 3.2e-75 253.2 0.7 4.2e-75 252.8 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EAQ83016.1 - 5.7e-40 134.8 0.0 1.9e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 EAQ83017.1 - 1.3e-23 82.4 0.4 1.3e-23 82.4 0.3 2.2 3 0 0 3 3 3 1 Hypoxia induced protein conserved region DUF4407 PF14362.1 EAQ83017.1 - 0.4 9.6 10.2 0.49 9.3 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SHR3_chaperone PF08229.6 EAQ83017.1 - 4.9 6.0 7.1 13 4.6 4.9 1.8 1 1 0 1 1 1 0 ER membrane protein SH3 TLD PF07534.11 EAQ83018.1 - 7e-29 100.5 0.0 2.4e-28 98.8 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 EAQ83018.1 - 4.3e-19 68.5 0.2 1.2e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal RPEL PF02755.10 EAQ83019.1 - 1.8e-23 81.1 0.5 2.7e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 RPEL repeat TrkH PF02386.11 EAQ83021.1 - 1.3e-71 241.0 1.0 9.3e-39 132.9 0.0 3.8 3 1 1 4 4 4 3 Cation transport protein FKBP_C PF00254.23 EAQ83021.1 - 2.6e-30 104.2 0.0 4.7e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.15 EAQ83022.1 - 1.9e-43 147.8 0.1 5.1e-43 146.4 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EAQ83022.1 - 2.5e-15 56.5 0.1 6.4e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EAQ83022.1 - 0.0028 17.6 0.0 0.0081 16.1 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Memo PF01875.12 EAQ83023.1 - 8.4e-67 224.9 0.0 1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Syntaxin PF00804.20 EAQ83024.1 - 6.7e-05 22.9 2.0 6.7e-05 22.9 1.4 3.1 1 1 1 2 2 1 1 Syntaxin SNARE PF05739.14 EAQ83024.1 - 0.00015 21.3 9.3 0.00015 21.3 6.4 3.8 4 1 0 4 4 4 1 SNARE domain DUF2951 PF11166.3 EAQ83024.1 - 0.0035 17.1 1.7 0.0035 17.1 1.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) DUF4064 PF13273.1 EAQ83024.1 - 0.014 15.5 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) P12 PF12669.2 EAQ83024.1 - 0.017 15.2 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Alpha_GJ PF03229.8 EAQ83024.1 - 0.024 14.9 0.8 0.065 13.5 0.6 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1183 PF06682.7 EAQ83024.1 - 0.031 13.8 0.3 0.031 13.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) GP41 PF00517.12 EAQ83024.1 - 0.075 12.5 0.3 0.075 12.5 0.2 2.3 3 0 0 3 3 3 0 Retroviral envelope protein DUF912 PF06024.7 EAQ83024.1 - 0.12 12.4 0.2 0.12 12.4 0.1 3.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PIG-P PF08510.7 EAQ83024.1 - 0.31 10.6 2.4 0.49 10.0 0.0 2.2 2 1 0 2 2 2 0 PIG-P DUF2370 PF10176.4 EAQ83024.1 - 0.44 9.8 5.3 0.065 12.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) Tweety PF04906.8 EAQ83024.1 - 1.7 6.9 5.6 0.17 10.2 0.6 1.7 2 0 0 2 2 2 0 Tweety EMP24_GP25L PF01105.19 EAQ83024.1 - 4.1 7.0 9.3 1.2 8.8 1.1 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TMPIT PF07851.8 EAQ83024.1 - 7.3 5.5 11.3 3.1 6.7 1.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein Gly-zipper_OmpA PF13436.1 EAQ83025.1 - 2.2 7.9 16.4 1.4 8.5 0.7 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain zf-Apc11 PF12861.2 EAQ83026.1 - 1.2e-45 153.3 11.2 1.4e-45 153.0 7.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EAQ83026.1 - 2.7e-34 117.1 10.5 3.3e-34 116.8 7.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EAQ83026.1 - 2.7e-08 33.4 17.2 2.2e-07 30.6 11.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ83026.1 - 4.6e-05 23.3 10.0 4.6e-05 23.3 6.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ83026.1 - 8.5e-05 22.1 14.2 0.00041 19.9 9.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ83026.1 - 0.00025 20.6 12.2 0.008 15.8 8.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ83026.1 - 0.00029 20.6 3.9 0.00029 20.6 2.7 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EAQ83026.1 - 0.0013 18.1 5.4 0.0019 17.6 3.7 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EAQ83026.1 - 0.0025 17.3 3.2 0.0025 17.3 2.3 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EAQ83026.1 - 0.013 15.2 16.1 0.25 11.1 11.4 2.5 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EAQ83026.1 - 0.018 14.9 16.9 0.43 10.5 11.7 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain Elf1 PF05129.8 EAQ83026.1 - 0.022 14.4 0.1 0.022 14.4 0.0 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_UBOX PF13445.1 EAQ83026.1 - 1.2 8.9 8.7 0.76 9.5 4.1 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.6 EAQ83026.1 - 1.6 8.7 13.5 0.39 10.7 6.3 2.1 1 1 1 2 2 2 0 RING-like domain Opy2 PF09463.5 EAQ83026.1 - 1.9 8.6 11.1 13 5.9 4.7 2.3 2 0 0 2 2 2 0 Opy2 protein DUF393 PF04134.7 EAQ83026.1 - 2.4 9.2 7.1 14 6.8 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function, DUF393 RINGv PF12906.2 EAQ83026.1 - 4.2 7.4 13.1 9.5 6.3 8.6 2.1 1 1 1 2 2 2 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 EAQ83026.1 - 5.7 6.9 9.9 3.6 7.6 4.1 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain zinc-ribbons_6 PF07191.7 EAQ83026.1 - 5.8 6.7 10.3 3 7.7 0.2 2.5 1 1 2 3 3 3 0 zinc-ribbons DZR PF12773.2 EAQ83026.1 - 7.9 6.3 12.7 7.9e+02 -0.1 8.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin PF00301.15 EAQ83026.1 - 9.4 6.2 11.2 6.3 6.7 0.5 3.4 2 1 1 3 3 3 0 Rubredoxin zf-HC5HC2H PF13771.1 EAQ83026.1 - 9.9 6.3 11.5 4.9 7.3 4.3 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain Abhydrolase_6 PF12697.2 EAQ83027.1 - 1.9e-31 109.7 1.8 2.3e-31 109.4 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ83027.1 - 3e-17 62.9 0.0 7.2e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ83027.1 - 2.4e-09 37.0 0.2 1.7e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ83027.1 - 1e-05 25.2 0.0 0.00014 21.6 0.0 2.5 2 1 1 3 3 3 1 Putative lysophospholipase GMC_oxred_N PF00732.14 EAQ83028.1 - 1.3e-59 201.7 0.0 1.7e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ83028.1 - 8.1e-32 110.4 0.0 1.6e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ83028.1 - 0.0001 21.3 0.8 0.00062 18.7 0.2 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ83028.1 - 0.00032 20.6 0.0 0.00094 19.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ83028.1 - 0.0027 16.6 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EAQ83028.1 - 0.0056 15.6 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EAQ83028.1 - 0.027 12.9 0.0 3.6 5.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_18 PF00704.23 EAQ83029.1 - 3.9e-29 102.1 0.0 4.9e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 EAQ83030.1 - 2.5e-05 23.9 2.7 0.068 13.0 0.4 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoplasmin PF03066.10 EAQ83030.1 - 0.028 13.9 3.9 0.048 13.1 2.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin PQQ_3 PF13570.1 EAQ83030.1 - 0.058 13.6 2.3 26 5.2 1.5 3.6 2 1 0 2 2 2 0 PQQ-like domain CDC45 PF02724.9 EAQ83030.1 - 0.34 8.8 4.4 0.45 8.4 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Inositol_P PF00459.20 EAQ83031.1 - 5.1e-68 229.3 0.1 7e-49 166.5 0.0 2.0 1 1 1 2 2 2 2 Inositol monophosphatase family RVT_2 PF07727.9 EAQ83032.1 - 7.9e-20 70.8 0.0 1.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4044 PF13253.1 EAQ83033.1 - 0.38 9.9 1.4 3.7 6.7 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) DZR PF12773.2 EAQ83033.1 - 0.49 10.2 5.7 0.94 9.3 3.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Myc_target_1 PF15179.1 EAQ83033.1 - 1.5 8.3 9.2 5.8 6.4 0.9 2.5 2 0 0 2 2 2 0 Myc target protein 1 AP_endonuc_2 PF01261.19 EAQ83034.1 - 1.5e-27 96.2 0.0 1.9e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_DH PF01488.15 EAQ83035.1 - 1.8e-14 53.9 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 EAQ83035.1 - 1.8e-10 40.7 0.0 6.7e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain OCD_Mu_crystall PF02423.10 EAQ83035.1 - 0.027 13.2 0.3 0.041 12.6 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.19 EAQ83036.1 - 3.3e-127 424.7 23.3 3.8e-127 424.6 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83036.1 - 2.4e-22 79.1 35.7 2.4e-22 79.1 24.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DHquinase_I PF01487.10 EAQ83037.1 - 3.4e-44 151.1 0.0 5.1e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EAQ83037.1 - 4.3e-21 74.7 0.1 1e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EAQ83037.1 - 1.6e-16 60.6 0.0 2.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EAQ83037.1 - 7.2e-11 42.3 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EAQ83037.1 - 0.0019 18.9 0.0 0.0044 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAQ83037.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EAQ83037.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAQ83037.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EAQ83038.1 - 0.00073 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Grp1_Fun34_YaaH PF01184.14 EAQ83039.1 - 1.4e-85 285.8 13.8 1.8e-85 285.5 9.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2244 PF10003.4 EAQ83039.1 - 1.3 8.3 7.2 0.17 11.2 2.0 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Ribosomal_S5 PF00333.15 EAQ83040.1 - 2.3e-28 97.7 2.1 2.3e-28 97.7 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EAQ83040.1 - 4.9e-20 70.5 0.0 4.9e-20 70.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain MARVEL PF01284.18 EAQ83041.1 - 3.2e-12 46.4 17.8 3.7e-12 46.2 12.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Abhydrolase_4 PF08386.5 EAQ83042.1 - 5.6e-16 58.3 0.0 1.4e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ83042.1 - 4e-08 33.0 0.1 4.9e-05 22.9 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ83042.1 - 1.9e-07 31.2 9.1 8.8e-07 29.0 4.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ83042.1 - 0.00056 19.6 0.0 0.0041 16.8 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FHA PF00498.21 EAQ83043.1 - 2.7e-05 24.2 0.1 5.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EAQ83043.1 - 0.0018 18.3 0.2 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Cyt-b5 PF00173.23 EAQ83044.1 - 2.4e-11 43.2 0.0 4.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tnp_P_element PF12017.3 EAQ83045.1 - 0.62 9.2 3.3 2.1 7.5 0.1 2.1 2 0 0 2 2 2 0 Transposase protein DnaJ-X PF14308.1 EAQ83046.1 - 1.4e-69 233.4 1.0 1.4e-69 233.4 0.7 2.2 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EAQ83046.1 - 1.6e-26 91.7 1.0 4.4e-26 90.3 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain PA-IL PF07828.7 EAQ83046.1 - 0.0063 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 PA-IL-like protein Zip PF02535.17 EAQ83046.1 - 0.034 13.1 4.3 0.015 14.3 1.1 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter SUZ PF12752.2 EAQ83046.1 - 0.067 13.7 7.7 0.058 13.9 3.2 2.5 2 0 0 2 2 2 0 SUZ domain SelP_N PF04592.9 EAQ83046.1 - 1 8.6 12.4 0.31 10.3 5.9 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region RmlD_sub_bind PF04321.12 EAQ83047.1 - 1.2e-14 53.9 0.0 2.7e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EAQ83047.1 - 2e-13 50.3 0.0 4.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ83047.1 - 0.00016 20.6 0.0 0.00033 19.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EAQ83047.1 - 0.01 15.7 0.1 0.023 14.6 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EAQ83047.1 - 0.076 11.9 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein SQS_PSY PF00494.14 EAQ83048.1 - 2.3e-39 135.3 0.0 7.2e-39 133.6 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase Orthopox_B11R PF07033.6 EAQ83048.1 - 0.11 12.0 0.4 0.27 10.7 0.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Peptidase_S8 PF00082.17 EAQ83049.1 - 6.3e-44 150.2 12.1 8.6e-44 149.7 8.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAQ83049.1 - 0.0035 17.8 0.3 0.0059 17.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Alpha_GJ PF03229.8 EAQ83051.1 - 0.074 13.3 4.7 0.22 11.8 3.3 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J F-box-like PF12937.2 EAQ83052.1 - 0.00037 20.1 0.5 0.0016 18.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like Mannosyl_trans PF05007.8 EAQ83053.1 - 1.5e-48 165.6 10.5 7.8e-32 110.9 4.7 2.2 1 1 1 2 2 2 2 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EAQ83053.1 - 1.1e-13 50.7 0.2 1.1e-13 50.7 0.1 2.1 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U Translin PF01997.11 EAQ83054.1 - 2.8e-65 219.6 0.0 3.2e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Translin family EF1_GNE PF00736.14 EAQ83055.1 - 2.6e-31 107.1 3.7 4.5e-31 106.3 2.6 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EAQ83055.1 - 8.4e-13 48.2 6.1 8.4e-13 48.2 4.2 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EAQ83055.1 - 0.0069 16.8 0.4 0.016 15.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ83055.1 - 0.015 15.2 1.2 0.034 14.1 0.1 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CTP_transf_2 PF01467.21 EAQ83057.1 - 0.00054 20.0 1.1 0.0048 16.9 0.7 2.4 1 1 0 1 1 1 1 Cytidylyltransferase Amidase PF01425.16 EAQ83058.1 - 2.2e-49 168.4 0.0 1.4e-47 162.6 0.0 2.5 1 1 1 2 2 2 2 Amidase GMC_oxred_N PF00732.14 EAQ83060.1 - 3.2e-58 197.2 0.0 4e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ83060.1 - 9.9e-34 116.6 0.0 1.5e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAQ83060.1 - 3.5e-05 22.8 1.4 0.0037 16.1 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EAQ83060.1 - 6.8e-05 22.8 0.1 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ83060.1 - 0.00011 21.3 3.6 0.0013 17.6 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ83060.1 - 0.00041 20.3 0.3 0.001 19.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ83060.1 - 0.00048 20.2 0.3 0.63 10.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ83060.1 - 0.00094 18.1 0.2 0.0014 17.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EAQ83060.1 - 0.0038 15.7 0.8 0.037 12.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EAQ83060.1 - 0.12 12.1 1.5 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EAQ83060.1 - 0.22 10.1 0.2 0.32 9.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Helitron_like_N PF14214.1 EAQ83061.1 - 4.5e-23 81.9 0.0 4.5e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ83061.1 - 2.1e-18 66.4 0.1 3.9e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ83061.1 - 0.00069 19.7 0.0 0.0044 17.1 0.0 2.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Patatin PF01734.17 EAQ83062.1 - 0.011 15.6 0.2 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase PIF1 PF05970.9 EAQ83063.1 - 1.7e-06 27.2 0.0 2.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Amidohydro_2 PF04909.9 EAQ83064.1 - 6.4e-17 61.9 0.6 2.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Ribosomal_L36 PF00444.13 EAQ83065.1 - 2.5e-16 59.3 13.8 4.1e-10 39.4 2.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L36 AAA_16 PF13191.1 EAQ83066.1 - 0.0003 20.8 0.1 0.0024 17.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EAQ83066.1 - 0.0004 20.2 0.0 0.00076 19.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.22 EAQ83066.1 - 0.00078 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EAQ83066.1 - 0.0023 17.1 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EAQ83066.1 - 0.0036 17.2 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 EAQ83066.1 - 0.0037 16.1 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EAQ83066.1 - 0.066 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EAQ83066.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.13 EAQ83066.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 EAQ83066.1 - 0.16 11.5 0.1 0.34 10.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 EAQ83066.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 AIG1 family CW_binding_1 PF01473.15 EAQ83069.1 - 4.4e-05 23.3 27.8 0.13 12.3 2.8 4.0 3 0 0 3 3 3 3 Putative cell wall binding repeat Ras PF00071.17 EAQ83071.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Ras family APH PF01636.18 EAQ83072.1 - 0.003 17.3 0.1 0.003 17.3 0.1 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family PLAC8 PF04749.12 EAQ83075.1 - 7.2e-12 45.8 5.7 9.8e-12 45.3 4.0 1.2 1 0 0 1 1 1 1 PLAC8 family p450 PF00067.17 EAQ83076.1 - 6.4e-22 77.7 0.0 1e-10 40.8 0.0 2.9 3 0 0 3 3 3 2 Cytochrome P450 PIG-S PF10510.4 EAQ83077.1 - 4.7e-153 510.5 0.0 5.4e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AMP-binding PF00501.23 EAQ83078.1 - 9.7e-74 248.2 0.0 1.3e-73 247.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ83078.1 - 4e-09 37.2 0.2 9.2e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.16 EAQ83079.1 - 3.6e-31 107.4 0.0 4.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EAQ83079.1 - 4e-11 42.3 0.2 7.3e-11 41.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EAQ83079.1 - 6.3e-10 38.7 0.0 8.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin BTB PF00651.26 EAQ83080.1 - 0.0027 17.6 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 EAQ83081.1 - 1.1e-16 60.5 27.4 3.1e-08 32.7 3.2 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ83081.1 - 0.0089 14.6 5.4 0.19 10.3 1.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Sulfatase PF00884.18 EAQ83082.1 - 1e-55 189.1 0.0 1.5e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EAQ83082.1 - 0.078 12.2 0.4 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Tautomerase_3 PF14832.1 EAQ83083.1 - 1.2e-46 158.1 0.1 1.3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme MULE PF10551.4 EAQ83084.1 - 1.6e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ83084.1 - 2.6e-05 22.9 0.1 5.9e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 Transposase, Mutator family F-box PF00646.28 EAQ83084.1 - 0.00045 19.8 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain FAR1 PF03101.10 EAQ83084.1 - 0.00055 20.3 0.1 0.0014 19.0 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain F-box-like PF12937.2 EAQ83084.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like AMP-binding PF00501.23 EAQ83085.1 - 2.8e-93 312.5 0.2 3.5e-93 312.2 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ83085.1 - 1.2e-12 48.5 0.2 3.9e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox PF00070.22 EAQ83086.1 - 9.9e-14 51.5 0.9 2.4e-12 47.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ83086.1 - 1e-08 35.3 0.0 0.0029 17.5 0.0 3.5 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ83086.1 - 1.4e-06 28.4 0.0 0.00068 19.7 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ83086.1 - 1.7e-05 23.9 0.0 4.1e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EAQ83086.1 - 0.0005 19.1 0.1 0.00084 18.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EAQ83086.1 - 0.012 14.5 0.2 0.028 13.3 0.2 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EAQ83086.1 - 0.031 12.9 0.0 0.39 9.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EAQ83086.1 - 0.14 11.9 0.3 9.6 5.9 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EAQ83086.1 - 0.15 10.4 0.3 0.47 8.8 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EAQ83086.1 - 0.28 10.1 1.7 3.7 6.5 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain PIF1 PF05970.9 EAQ83087.1 - 8.1e-16 57.9 0.0 1.2e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ83087.1 - 0.00027 18.8 0.0 0.00068 17.5 0.0 1.5 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EAQ83087.1 - 0.00086 19.4 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ83087.1 - 0.14 11.9 0.6 0.78 9.5 0.4 2.1 1 1 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EAQ83087.1 - 0.26 10.7 0.6 2.5 7.5 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RVT_1 PF00078.22 EAQ83089.1 - 6.9e-21 74.5 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.20 EAQ83091.1 - 7.2e-10 39.0 0.3 8.4e-09 35.5 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase DUF2360 PF10152.4 EAQ83091.1 - 0.11 12.7 1.5 0.17 12.1 0.2 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3336 PF11815.3 EAQ83092.1 - 1.8e-42 144.3 0.8 2.8e-42 143.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EAQ83092.1 - 6.7e-22 78.4 0.0 1.3e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_5 PF12695.2 EAQ83093.1 - 0.00037 20.2 0.1 0.0019 17.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ83093.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EAQ83094.1 - 2.1e-13 50.3 0.0 2.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ83094.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family 3D PF06725.6 EAQ83095.1 - 0.024 14.6 0.1 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 3D domain CorA PF01544.13 EAQ83096.1 - 0.011 14.7 8.1 0.018 14.0 5.5 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1279 PF06916.8 EAQ83096.1 - 0.034 14.4 0.2 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) L31 PF09784.4 EAQ83096.1 - 0.13 12.3 0.2 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF3445 PF11927.3 EAQ83097.1 - 3.7e-41 141.1 0.0 5.9e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Tannase PF07519.6 EAQ83099.1 - 2e-60 204.8 0.0 8e-53 179.7 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase Sugar_tr PF00083.19 EAQ83100.1 - 2.3e-88 296.7 24.8 2.7e-88 296.5 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83100.1 - 5.2e-14 51.7 46.4 1.1e-07 30.8 8.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Crystall PF00030.14 EAQ83101.1 - 0.00021 21.0 0.7 0.00039 20.2 0.5 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin SET PF00856.23 EAQ83102.1 - 1.3e-13 51.5 0.0 4.2e-13 49.9 0.0 1.8 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 EAQ83102.1 - 0.0071 16.2 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat SAF PF08666.7 EAQ83102.1 - 0.066 13.6 0.1 3.2 8.2 0.0 2.3 2 0 0 2 2 2 0 SAF domain TPR_10 PF13374.1 EAQ83102.1 - 0.26 11.3 3.6 0.32 11.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ83102.1 - 0.31 11.7 3.4 0.6 10.8 2.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FA_desaturase PF00487.19 EAQ83105.1 - 0.088 12.2 1.4 0.099 12.0 0.4 1.6 1 1 0 1 1 1 0 Fatty acid desaturase HET PF06985.6 EAQ83106.1 - 0.016 15.3 0.3 0.24 11.5 0.2 2.4 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) IU_nuc_hydro PF01156.14 EAQ83107.1 - 2.2e-31 109.2 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cyclin PF08613.6 EAQ83108.1 - 6e-39 133.8 0.0 9.8e-23 81.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.21 EAQ83110.1 - 6.3e-49 165.8 0.1 7.2e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Pox_A51 PF04948.8 EAQ83110.1 - 0.18 10.4 0.1 0.31 9.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A51 protein APH PF01636.18 EAQ83112.1 - 0.0002 21.1 1.3 0.14 11.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family SET PF00856.23 EAQ83113.1 - 9.1e-12 45.5 0.1 1.2e-10 41.9 0.1 2.3 1 1 0 1 1 1 1 SET domain Terpene_synth PF01397.16 EAQ83113.1 - 0.044 13.1 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Pkinase PF00069.20 EAQ83114.1 - 5.1e-49 166.7 4.3 6.6e-48 163.1 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83114.1 - 1.3e-29 103.0 0.0 1.3e-23 83.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ83114.1 - 4.2e-08 32.4 0.0 6.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ83114.1 - 0.042 12.9 0.2 0.097 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ83114.1 - 0.049 13.3 0.9 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.25 EAQ83115.1 - 8.8e-10 38.3 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain CENP-B_dimeris PF09026.5 EAQ83115.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAPPC10 PF12584.3 EAQ83116.1 - 4.2e-16 58.7 0.0 1.7e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 IF-2B PF01008.12 EAQ83118.1 - 1.3e-71 240.9 0.7 1.5e-71 240.6 0.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3620 PF12281.3 EAQ83118.1 - 0.042 13.5 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) Peptidase_M20 PF01546.23 EAQ83119.1 - 3.7e-15 55.9 0.0 3.7e-14 52.6 0.0 2.2 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAQ83119.1 - 2.8e-08 33.4 0.1 6.9e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EAQ83119.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Prenyltrans PF00432.16 EAQ83120.1 - 1.3e-19 69.4 13.2 1.1e-10 40.8 0.1 4.9 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAQ83120.1 - 5e-14 52.6 0.0 6.6e-08 32.9 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAQ83120.1 - 8.1e-08 32.2 0.0 0.001 19.0 0.0 3.1 2 1 0 2 2 2 2 Prenyltransferase-like Ilm1 PF10311.4 EAQ83121.1 - 5.9e-50 169.0 0.4 1.7e-33 115.4 0.0 2.2 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 NatB_MDM20 PF09797.4 EAQ83122.1 - 4.9e-100 334.7 0.0 6.8e-100 334.3 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit CHCH PF06747.8 EAQ83122.1 - 6e-05 22.8 1.2 0.00013 21.7 0.8 1.7 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EAQ83122.1 - 0.00048 20.2 0.9 0.0013 18.8 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Striatin PF08232.7 EAQ83123.1 - 0.08 13.2 3.0 0.19 12.0 2.1 1.6 1 1 0 1 1 1 0 Striatin family Glyco_hydro_76 PF03663.9 EAQ83124.1 - 1.6e-117 393.0 5.1 4.9e-66 223.6 2.7 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Zn_clus PF00172.13 EAQ83126.1 - 2.4e-07 30.5 8.9 4.7e-07 29.6 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ83126.1 - 3e-05 23.0 0.0 0.00012 21.0 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF604 PF04646.7 EAQ83127.1 - 0.0034 16.6 0.0 0.18 10.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function, DUF604 RabGAP-TBC PF00566.13 EAQ83128.1 - 1.8e-30 106.0 0.0 2.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CVNH PF08881.5 EAQ83129.1 - 9.2e-23 80.4 0.2 1.1e-22 80.1 0.2 1.1 1 0 0 1 1 1 1 CVNH domain FA_desaturase PF00487.19 EAQ83131.1 - 1.8e-19 70.2 11.0 2.5e-19 69.7 7.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EAQ83131.1 - 7.4e-09 35.7 0.1 2e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3474) DUF2809 PF10990.3 EAQ83131.1 - 0.076 13.4 2.2 3.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2809) eIF2A PF08662.6 EAQ83133.1 - 2.9e-40 138.0 4.3 4.3e-38 130.9 0.3 4.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EAQ83133.1 - 5.5e-06 26.2 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ83133.1 - 0.0002 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ83133.1 - 0.00032 20.2 0.0 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EAQ83133.1 - 0.004 16.9 0.1 15 5.6 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EAQ83134.1 - 4.3e-135 451.0 8.7 5.1e-135 450.8 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 EAQ83134.1 - 0.069 12.5 0.2 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Glyco_hydro_61 PF03443.9 EAQ83135.1 - 7.8e-37 127.1 0.0 9e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_12 PF13424.1 EAQ83136.1 - 1.3e-108 355.0 39.9 6e-19 67.7 2.1 7.0 2 1 7 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ83136.1 - 1e-85 279.4 12.4 4.7e-10 39.0 0.0 10.3 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ83136.1 - 1.8e-47 157.0 28.7 9e-07 28.2 0.4 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ83136.1 - 1.5e-42 140.0 22.0 2e-05 24.0 0.2 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ83136.1 - 6.9e-38 128.1 16.7 6.3e-09 35.3 0.2 6.0 4 1 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 EAQ83136.1 - 6.7e-34 113.0 31.7 6.3e-06 25.7 0.7 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ83136.1 - 3.4e-31 107.2 12.0 7.9e-08 32.7 3.2 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ83136.1 - 3.5e-29 98.6 14.4 0.002 18.6 0.3 10.7 7 3 3 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ83136.1 - 1.4e-24 86.2 16.3 1.6e-05 25.1 0.1 7.6 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ83136.1 - 1.4e-24 83.9 33.3 0.004 16.8 0.3 9.6 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ83136.1 - 2.5e-18 64.6 10.7 0.031 14.4 0.0 10.3 8 3 1 9 9 9 3 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ83136.1 - 3.8e-16 57.7 0.0 0.052 14.0 0.0 8.7 9 0 0 9 9 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EAQ83136.1 - 5.2e-14 52.1 8.0 5.9e-05 23.1 0.7 5.1 3 1 4 7 7 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAQ83136.1 - 9.6e-11 41.4 30.3 0.9 10.1 0.1 9.1 8 0 0 8 8 8 4 Tetratricopeptide repeat PPR PF01535.15 EAQ83136.1 - 1.1e-08 34.5 6.8 7.6 6.7 0.0 8.1 9 0 0 9 9 7 0 PPR repeat DUF2225 PF09986.4 EAQ83136.1 - 7.3e-07 28.8 7.7 0.012 15.0 0.1 3.8 1 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) SPO22 PF08631.5 EAQ83136.1 - 1.4e-05 24.3 0.2 0.03 13.3 0.0 2.9 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like SNAP PF14938.1 EAQ83136.1 - 1.7e-05 24.1 7.8 0.18 10.9 0.8 4.5 3 1 1 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_21 PF09976.4 EAQ83136.1 - 2.1e-05 24.4 12.2 0.21 11.5 0.3 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ83136.1 - 0.00011 21.1 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Tcf25 PF04910.9 EAQ83136.1 - 0.018 14.0 0.2 31 3.3 0.0 4.7 2 1 5 7 7 7 0 Transcriptional repressor TCF25 RPN7 PF10602.4 EAQ83136.1 - 0.024 14.0 7.6 5.3 6.3 0.1 5.0 4 2 2 6 6 6 0 26S proteasome subunit RPN7 DS PF01916.12 EAQ83136.1 - 0.043 12.9 0.0 0.87 8.6 0.0 2.7 2 1 1 3 3 3 0 Deoxyhypusine synthase Coatomer_E PF04733.9 EAQ83136.1 - 0.93 8.6 4.3 30 3.6 0.1 4.2 4 1 1 5 5 5 0 Coatomer epsilon subunit BTB_2 PF02214.17 EAQ83140.1 - 3.6e-09 36.6 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EAQ83140.1 - 0.00027 20.9 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain B12D PF06522.6 EAQ83140.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Glyco_hydro_43 PF04616.9 EAQ83141.1 - 2.6e-53 180.9 1.7 3.1e-53 180.7 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3242 PF11586.3 EAQ83141.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Pkinase PF00069.20 EAQ83142.1 - 7e-22 77.8 0.0 1.3e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83142.1 - 0.005 15.9 0.0 0.0091 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4419 PF14388.1 EAQ83143.1 - 8.8e-84 281.2 0.0 1.1e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glyco_hydro_71 PF03659.9 EAQ83144.1 - 7.8e-138 459.1 6.0 1.1e-137 458.5 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PP2C PF00481.16 EAQ83145.1 - 1.2e-07 31.3 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Vmethyltransf_C PF08456.5 EAQ83145.1 - 0.085 12.2 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Viral methyltransferase C-terminal FAD_binding_3 PF01494.14 EAQ83146.1 - 7e-10 38.4 0.1 0.00018 20.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EAQ83146.1 - 6.6e-09 35.1 0.0 1.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ83146.1 - 3e-08 33.5 0.2 9.7e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ83146.1 - 4.4e-07 29.1 0.1 8.3e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ83146.1 - 3e-06 27.2 0.0 6.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ83146.1 - 8.7e-06 26.0 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ83146.1 - 1.3e-05 24.4 0.0 2.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ83146.1 - 1.3e-05 23.8 0.0 1.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EAQ83146.1 - 0.00092 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EAQ83146.1 - 0.00093 18.1 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EAQ83146.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EAQ83146.1 - 0.023 13.6 0.1 0.054 12.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EAQ83146.1 - 0.048 13.3 0.1 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EAQ83146.1 - 0.049 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EAQ83146.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EAQ83146.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GCR1_C PF12550.3 EAQ83148.1 - 3.3e-23 81.3 0.7 6.9e-23 80.3 0.5 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SWIB PF02201.13 EAQ83149.1 - 5.4e-28 96.4 0.9 1.7e-27 94.8 0.1 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EAQ83149.1 - 4.6e-15 55.1 2.4 1.1e-14 53.8 1.7 1.7 1 0 0 1 1 1 1 DEK C terminal domain U79_P34 PF03064.11 EAQ83149.1 - 0.014 14.9 5.7 0.022 14.2 3.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ATP-gua_Ptrans PF00217.14 EAQ83149.1 - 0.032 13.5 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain SRP-alpha_N PF04086.8 EAQ83149.1 - 0.72 9.1 11.2 1 8.7 7.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 EAQ83150.1 - 6.7e-25 87.7 0.0 1.3e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83150.1 - 4e-11 42.4 0.0 6.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2380 PF09533.5 EAQ83150.1 - 0.12 11.7 0.8 0.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) Glyco_hydro_10 PF00331.15 EAQ83151.1 - 1.1e-83 280.9 2.5 9.8e-83 277.8 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EAQ83151.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase zf-C3HC4_3 PF13920.1 EAQ83152.1 - 1.1e-05 25.0 9.1 1.1e-05 25.0 6.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribonuc_2-5A PF06479.7 EAQ83153.1 - 7.1e-45 152.0 0.0 1.2e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EAQ83153.1 - 4e-37 127.7 0.0 6.6e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83153.1 - 5.8e-17 61.6 0.0 5.9e-16 58.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EAQ83153.1 - 4e-07 29.2 0.7 0.001 18.5 0.0 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 EAQ83153.1 - 1.1e-05 25.0 0.1 3.4e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 EAQ83153.1 - 0.00051 19.1 0.0 0.00088 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EAQ83153.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Acyl-CoA_dh_1 PF00441.19 EAQ83154.1 - 2.4e-32 112.1 1.1 3.4e-32 111.6 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ83154.1 - 1.4e-18 66.0 1.6 2.7e-18 65.2 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EAQ83154.1 - 1.5e-09 38.3 0.9 4.9e-09 36.7 0.6 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAQ83154.1 - 3.3e-05 24.1 0.4 6.2e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_11 PF08241.7 EAQ83155.1 - 3.7e-13 49.7 0.0 7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ83155.1 - 8.7e-11 42.0 0.0 1.9e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ83155.1 - 1.1e-09 37.8 0.0 1.9e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EAQ83155.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ83155.1 - 2.9e-07 30.2 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ83155.1 - 3.6e-06 27.3 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ83155.1 - 9.4e-06 25.6 0.3 2.1e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ83155.1 - 0.00074 20.0 0.0 0.0015 19.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EAQ83155.1 - 0.0023 16.3 0.0 0.003 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EAQ83155.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain RVT_1 PF00078.22 EAQ83156.1 - 4.3e-32 111.2 0.0 8.4e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ83156.1 - 3.9e-22 78.0 0.0 4e-21 74.8 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ83156.1 - 3.9e-09 36.7 0.1 7.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ83156.1 - 0.0059 16.9 4.2 0.072 13.4 0.7 2.9 1 1 1 2 2 2 2 SlyX RNase_H PF00075.19 EAQ83156.1 - 0.041 14.2 0.1 0.093 13.0 0.1 1.6 1 0 0 1 1 1 0 RNase H CorA PF01544.13 EAQ83156.1 - 0.061 12.3 1.9 0.12 11.3 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ83156.1 - 0.34 10.9 5.9 0.11 12.5 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Helitron_like_N PF14214.1 EAQ83159.1 - 1.2e-50 171.7 2.0 3.1e-50 170.4 1.4 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ83159.1 - 4.4e-18 65.3 0.0 4e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ83159.1 - 0.0047 16.5 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ83159.1 - 0.0081 16.2 0.0 0.028 14.5 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ83159.1 - 0.022 14.5 0.1 0.069 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 EAQ83159.1 - 0.089 12.6 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 Torsin Herpes_Helicase PF02689.9 EAQ83159.1 - 0.99 7.0 0.0 2.3 5.8 0.0 1.5 2 0 0 2 2 2 0 Helicase XPA_N PF01286.13 EAQ83159.1 - 1.6 8.4 8.9 0.043 13.5 1.3 2.0 2 0 0 2 2 2 0 XPA protein N-terminal DUF1956 PF09209.6 EAQ83160.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) Clr5 PF14420.1 EAQ83162.1 - 2.8e-16 59.1 0.2 6.1e-16 58.0 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_14 PF13428.1 EAQ83162.1 - 0.1 13.2 0.6 31 5.5 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3632 PF12311.3 EAQ83163.1 - 1.7e-45 155.1 0.4 2.8e-45 154.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Med3 PF11593.3 EAQ83163.1 - 0.038 13.2 6.1 0.038 13.2 4.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribonuclease PF00545.15 EAQ83164.1 - 1.4e-19 69.9 1.1 2.1e-19 69.3 0.1 1.7 2 0 0 2 2 2 1 ribonuclease Serglycin PF04360.7 EAQ83164.1 - 0.34 10.6 2.5 0.53 10.0 1.7 1.4 1 0 0 1 1 1 0 Serglycin PAT1 PF09770.4 EAQ83166.1 - 4.7 5.3 11.3 5.2 5.1 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF2_N PF00176.18 EAQ83167.1 - 3.4e-09 35.9 0.0 0.0016 17.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ83167.1 - 4.9e-06 26.3 0.0 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mito_fiss_reg PF05308.6 EAQ83167.1 - 7.7 5.8 7.3 17 4.6 5.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator SET PF00856.23 EAQ83168.1 - 2.5e-15 57.1 0.0 3.4e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 SET domain Dynamin_N PF00350.18 EAQ83169.1 - 1.3e-28 99.9 0.0 3.4e-28 98.5 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EAQ83169.1 - 1.9e-05 24.5 0.0 0.00016 21.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 EAQ83169.1 - 0.0016 17.3 0.0 0.31 9.7 0.0 2.6 2 1 1 3 3 3 2 Dynamin central region FeoB_N PF02421.13 EAQ83169.1 - 0.04 13.1 0.0 3 7.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EAQ83169.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EAQ83169.1 - 0.054 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 EAQ83169.1 - 0.068 12.2 0.0 0.99 8.4 0.0 2.5 2 0 0 2 2 2 0 AIG1 family HR1 PF02185.11 EAQ83169.1 - 0.14 11.9 1.3 0.32 10.7 0.9 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_29 PF13555.1 EAQ83169.1 - 0.15 11.6 0.0 0.15 11.6 0.0 3.2 2 1 0 3 3 3 0 P-loop containing region of AAA domain IncA PF04156.9 EAQ83169.1 - 0.23 11.0 1.4 0.53 9.8 1.0 1.5 1 0 0 1 1 1 0 IncA protein RVT_1 PF00078.22 EAQ83170.1 - 4.6e-32 111.1 0.0 9.1e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ83170.1 - 4e-22 78.0 0.0 6e-21 74.2 0.0 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ83170.1 - 7.3e-09 35.9 0.1 1.4e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ83170.1 - 0.006 16.9 4.3 0.12 12.7 2.3 2.8 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ83170.1 - 0.047 12.7 1.9 0.1 11.5 1.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mnd1 PF03962.10 EAQ83170.1 - 0.21 11.2 1.5 0.52 9.9 1.0 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4226 PF10774.4 EAQ83170.1 - 0.25 11.4 5.9 0.094 12.7 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) RVT_1 PF00078.22 EAQ83172.1 - 1e-27 96.8 0.0 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.26 EAQ83173.1 - 2e-19 69.2 0.0 1e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ83173.1 - 1.2e-14 54.2 0.0 5.4e-12 45.5 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EAQ83173.1 - 0.0075 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain TrmB PF01978.14 EAQ83173.1 - 0.065 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HemN_C PF06969.11 EAQ83173.1 - 0.068 13.2 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 HemN C-terminal domain DUF2250 PF10007.4 EAQ83173.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DDE_1 PF03184.14 EAQ83174.1 - 1.3e-49 168.3 0.0 1.9e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ83174.1 - 1.3e-08 34.1 0.2 5.3e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain UvrD_C_2 PF13538.1 EAQ83174.1 - 0.0052 16.8 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HTH_Tnp_Tc5 PF03221.11 EAQ83174.1 - 0.0094 15.7 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TIM PF00121.13 EAQ83174.1 - 0.24 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Triosephosphate isomerase zf-MYND PF01753.13 EAQ83175.1 - 1.8e-09 37.3 10.8 2.7e-09 36.7 7.5 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAQ83175.1 - 0.095 12.5 4.1 0.2 11.5 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_61 PF03443.9 EAQ83177.1 - 8.7e-30 104.1 0.0 9.8e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Big_3_4 PF13754.1 EAQ83177.1 - 0.041 14.2 0.2 0.087 13.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) CBM_48 PF02922.13 EAQ83177.1 - 0.11 12.5 0.2 0.57 10.2 0.1 2.2 2 1 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SET PF00856.23 EAQ83178.1 - 2e-07 31.4 0.0 4.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 SET domain Metal_resist PF13801.1 EAQ83178.1 - 0.03 14.3 0.1 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Orthopox_C10L PF07020.6 EAQ83179.1 - 0.23 12.0 2.3 1.3 9.6 1.4 2.2 1 1 0 1 1 1 0 Orthopoxvirus C10L protein adh_short_C2 PF13561.1 EAQ83180.1 - 2.3e-17 63.5 1.7 2.3e-09 37.3 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ83180.1 - 1.8e-05 24.7 0.8 3e-05 24.0 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAQ83180.1 - 0.0017 18.4 0.1 0.0033 17.4 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EAQ83180.1 - 0.0026 17.4 0.1 0.0045 16.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ83180.1 - 0.0068 16.1 0.4 0.019 14.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EAQ83180.1 - 0.048 12.8 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EAQ83180.1 - 0.052 13.2 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ83180.1 - 0.064 13.6 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ketoacyl-synt PF00109.21 EAQ83181.1 - 6.2e-68 229.0 3.2 5.2e-67 225.9 0.0 3.4 3 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ83181.1 - 3.1e-60 202.9 0.1 1.2e-59 201.0 0.1 2.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAQ83181.1 - 2.8e-48 164.0 0.1 2.8e-48 164.0 0.1 2.8 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EAQ83181.1 - 4.8e-39 134.2 5.1 1.9e-29 102.7 0.0 2.9 2 1 1 3 3 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EAQ83181.1 - 1.6e-20 73.0 0.1 3.1e-14 52.8 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EAQ83181.1 - 3.9e-14 52.3 0.0 5.6e-13 48.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.16 EAQ83181.1 - 4.1e-14 52.6 4.6 1.3e-12 47.7 1.2 2.9 3 0 0 3 3 3 1 Acyl transferase domain Methyltransf_12 PF08242.7 EAQ83181.1 - 2.1e-11 44.1 0.0 6.5e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ83181.1 - 1.2e-09 38.1 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ83181.1 - 1.6e-08 35.1 0.0 5.4e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ83181.1 - 1e-06 28.9 0.3 3.2e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EAQ83181.1 - 1.9e-06 28.2 0.0 0.00022 21.6 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EAQ83181.1 - 7.9e-06 25.0 0.0 8.9e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 EAQ83181.1 - 2.8e-05 23.7 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ83181.1 - 9.1e-05 22.4 0.2 0.00039 20.4 0.1 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ83181.1 - 0.0011 19.2 0.0 0.0062 16.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.1 EAQ83181.1 - 0.0012 18.7 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_28 PF02636.12 EAQ83181.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Polysacc_synt_2 PF02719.10 EAQ83181.1 - 0.016 14.0 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_N PF08240.7 EAQ83181.1 - 0.021 14.5 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Shikimate_DH PF01488.15 EAQ83181.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EAQ83181.1 - 0.27 10.4 0.0 0.5 9.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ketoacyl-synt PF00109.21 EAQ83182.1 - 8.1e-48 163.1 0.0 2.8e-47 161.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ83182.1 - 1.9e-28 99.7 0.0 9.1e-28 97.4 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 EAQ83182.1 - 4.2e-24 84.8 0.0 6.4e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EAQ83182.1 - 2.2e-14 53.7 0.0 5.8e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ83182.1 - 1e-09 38.3 0.0 1.7e-08 34.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 EAQ83182.1 - 1.2e-09 37.9 0.2 3.2e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_31 PF13847.1 EAQ83182.1 - 2e-09 37.2 0.0 4.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ83182.1 - 2.7e-08 33.9 4.3 2.9e-07 30.6 1.6 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EAQ83182.1 - 9.1e-06 26.0 0.0 4e-05 24.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EAQ83182.1 - 7.6e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RrnaAD PF00398.15 EAQ83182.1 - 0.00068 18.7 0.0 0.0023 16.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EAQ83182.1 - 0.0009 19.8 0.0 0.0038 17.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 EAQ83182.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EAQ83182.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 KR domain Methyltransf_26 PF13659.1 EAQ83182.1 - 0.018 15.0 0.0 0.062 13.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EAQ83182.1 - 0.073 11.9 0.0 0.38 9.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NodS PF05401.6 EAQ83182.1 - 0.081 12.3 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Nodulation protein S (NodS) NmrA PF05368.8 EAQ83182.1 - 0.46 9.6 0.0 1.3 8.2 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family DUF1033 PF06279.6 EAQ83182.1 - 6.5 6.6 3.5 14 5.5 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) MFS_1 PF07690.11 EAQ83183.1 - 6.8e-37 126.9 43.4 6.8e-37 126.9 30.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PhrC_PhrF PF11131.3 EAQ83183.1 - 1.9 8.1 9.1 0.065 12.8 0.6 2.6 2 0 0 2 2 2 0 Rap-phr extracellular signalling Trp_halogenase PF04820.9 EAQ83184.1 - 7.3e-26 90.8 0.1 3e-13 49.2 0.1 2.5 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EAQ83184.1 - 1.2e-11 44.2 0.3 1.1e-10 41.1 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ83184.1 - 7e-07 29.3 0.0 1.2e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ83184.1 - 4.7e-06 25.9 0.8 6.1e-05 22.2 0.4 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EAQ83184.1 - 8.9e-06 24.8 0.0 0.00027 19.9 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ83184.1 - 3e-05 23.9 0.0 0.00012 22.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ83184.1 - 0.00018 20.5 0.1 0.00036 19.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EAQ83184.1 - 0.00048 18.7 0.1 0.0008 17.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EAQ83184.1 - 0.0012 17.7 0.1 0.002 17.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EAQ83184.1 - 0.0048 16.9 0.1 0.019 15.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ83184.1 - 0.0071 16.7 0.1 0.027 14.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ83184.1 - 0.0085 15.2 0.0 0.058 12.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family ThiF PF00899.16 EAQ83184.1 - 0.031 14.0 0.2 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 EAQ83184.1 - 0.094 12.9 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EAQ83184.1 - 0.16 10.8 0.2 0.8 8.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.13 EAQ83185.1 - 4.6e-10 38.8 0.0 1.4e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ83185.1 - 1e-08 34.8 8.6 2.3e-08 33.8 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 EAQ83187.1 - 1.2e-159 531.5 0.0 1.4e-159 531.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EAQ83187.1 - 1.4e-10 41.1 0.0 3.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Myb_DNA-binding PF00249.26 EAQ83189.1 - 2.1e-17 62.8 8.8 6.1e-09 35.7 0.1 4.8 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ83189.1 - 2.9e-14 52.8 11.8 1.4e-10 41.1 0.1 3.9 3 1 1 4 4 4 2 Myb-like DNA-binding domain AAA_16 PF13191.1 EAQ83191.1 - 1.5e-05 25.0 1.5 0.00062 19.8 1.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EAQ83191.1 - 7.6e-05 22.5 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EAQ83191.1 - 0.0018 17.7 0.1 0.0083 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ83191.1 - 0.015 15.4 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain 4HBT_3 PF13622.1 EAQ83191.1 - 0.051 13.3 0.2 0.071 12.8 0.2 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF815 PF05673.8 EAQ83191.1 - 0.076 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.24 EAQ83191.1 - 0.12 12.5 0.1 0.31 11.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mito_fiss_reg PF05308.6 EAQ83191.1 - 0.21 10.9 7.3 0.38 10.0 5.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans_2 PF11951.3 EAQ83192.1 - 1.8e-30 105.8 1.9 3.8e-18 65.2 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ83192.1 - 1.9e-08 34.0 11.5 3.2e-08 33.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSDC PF12588.3 EAQ83194.1 - 2.1e-51 173.2 0.0 3.2e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAQ83194.1 - 1.8e-34 118.8 0.0 3.6e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase zf-C2H2_3 PF13878.1 EAQ83194.1 - 2.7e-05 23.6 0.0 6.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Biotin_lipoyl_2 PF13533.1 EAQ83194.1 - 0.0003 20.3 0.0 0.073 12.7 0.1 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.1 EAQ83194.1 - 0.12 12.1 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Vma12 PF11712.3 EAQ83195.1 - 2.6e-38 130.9 0.0 4.4e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1358 PF07096.6 EAQ83195.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) polyprenyl_synt PF00348.12 EAQ83196.1 - 4.9e-55 186.1 0.3 1.1e-50 171.9 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EAQ83196.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SQS_PSY PF00494.14 EAQ83196.1 - 0.035 13.4 0.7 0.079 12.2 0.5 1.7 1 1 0 1 1 1 0 Squalene/phytoene synthase ADH_zinc_N PF00107.21 EAQ83197.1 - 2.3e-22 78.9 0.0 3.9e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ83197.1 - 8.8e-06 26.6 0.1 3.4e-05 24.7 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Amidohydro_1 PF01979.15 EAQ83198.1 - 4.6e-19 69.2 0.7 1.6e-12 47.7 0.2 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EAQ83198.1 - 4.2e-15 56.5 3.4 3e-10 40.6 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EAQ83198.1 - 2.7e-09 36.6 0.0 7e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EAQ83198.1 - 3.5e-08 33.1 0.9 8.6e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family PIP5K PF01504.13 EAQ83199.1 - 1.5e-86 289.6 0.1 2e-86 289.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.12 EAQ83200.1 - 5.6e-23 80.7 2.2 6.8e-23 80.4 1.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EAQ83200.1 - 0.0044 17.0 0.3 0.006 16.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.4 EAQ83201.1 - 2.9e-50 170.0 6.1 3.3e-50 169.8 4.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CHD5 PF04420.9 EAQ83201.1 - 0.022 14.4 0.8 0.037 13.6 0.6 1.3 1 0 0 1 1 1 0 CHD5-like protein TrbE PF11100.3 EAQ83201.1 - 0.031 14.1 5.7 0.047 13.5 2.9 2.0 1 1 1 2 2 2 0 Conjugal transfer protein TrbE GRA6 PF05084.8 EAQ83201.1 - 0.53 9.7 5.6 0.92 8.9 3.9 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Acyl-CoA_dh_N PF02771.11 EAQ83202.1 - 8.8e-24 84.2 0.2 1.5e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EAQ83202.1 - 1.9e-17 63.7 0.1 3.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ83202.1 - 8.9e-05 21.9 0.0 0.00025 20.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EAQ83202.1 - 0.00024 21.3 0.2 0.00044 20.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 EAQ83203.1 - 2.4e-51 172.8 0.0 2.7e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ83203.1 - 3e-05 23.7 0.0 3.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAQ83203.1 - 0.0017 18.2 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EAQ83203.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 EAQ83205.1 - 1.1e-31 109.8 0.0 2.4e-31 108.7 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAQ83205.1 - 1.8e-20 72.7 0.0 5.9e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EAQ83205.1 - 6.2e-17 61.8 9.7 6.2e-17 61.8 6.7 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EAQ83205.1 - 0.0038 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain XPG_I PF00867.13 EAQ83206.1 - 9.6e-30 102.5 0.0 2.3e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAQ83206.1 - 2.9e-20 72.4 0.0 8.8e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EAQ83206.1 - 7.6e-06 26.1 0.3 5e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 EAQ83206.1 - 0.051 12.3 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Acyl-CoA_dh_1 PF00441.19 EAQ83207.1 - 7.1e-41 139.8 0.1 9.9e-41 139.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ83207.1 - 6.1e-21 73.6 0.2 1.1e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EAQ83207.1 - 1.3e-16 60.1 0.3 2.3e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EAQ83207.1 - 8.6e-16 58.5 0.0 1.9e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAQ83207.1 - 2.5e-07 31.0 0.0 5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_60s PF00428.14 EAQ83207.1 - 0.059 13.7 6.1 0.12 12.7 4.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cys_rich_VLP PF14194.1 EAQ83207.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP Tim17 PF02466.14 EAQ83208.1 - 5.1e-15 55.6 6.2 1.6e-14 54.0 4.3 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.24 EAQ83209.1 - 1.2e-27 96.6 0.0 2.3e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ83209.1 - 2.5e-10 40.2 2.9 0.00031 20.2 0.2 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EAQ83209.1 - 4.5e-09 35.5 0.0 0.0066 15.8 0.0 3.7 3 0 0 3 3 3 2 A repeated domain in UCH-protein PUB PF09409.5 EAQ83209.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 PUB domain IF2_N PF04760.10 EAQ83209.1 - 0.082 12.5 2.4 0.37 10.4 0.0 2.8 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region MutS_V PF00488.16 EAQ83210.1 - 4.1e-97 324.2 0.1 6.2e-97 323.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAQ83210.1 - 6.3e-39 133.8 3.1 7.1e-39 133.7 0.7 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EAQ83210.1 - 2.1e-20 73.1 0.5 8.6e-20 71.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EAQ83210.1 - 2.9e-18 65.8 1.3 1.1e-17 63.9 0.3 2.5 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 EAQ83210.1 - 3.1e-17 62.6 0.0 1.6e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 MutS domain I Peptidase_M16 PF00675.15 EAQ83210.1 - 0.072 12.8 0.1 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) tRNA_m1G_MT PF01746.16 EAQ83211.1 - 3.1e-29 101.8 4.7 1.5e-21 76.8 0.0 3.0 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase RR_TM4-6 PF06459.7 EAQ83211.1 - 3.4 7.4 9.0 5.8 6.7 6.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_primase_S PF01896.14 EAQ83212.1 - 7.6e-53 178.2 0.2 1.3e-52 177.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Pkinase PF00069.20 EAQ83214.1 - 3.9e-39 134.3 0.2 2.2e-33 115.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83214.1 - 2.4e-25 89.0 0.3 2.1e-23 82.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ83214.1 - 4.3e-05 22.6 0.0 0.00035 19.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EAQ83214.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ83214.1 - 0.033 13.8 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 EAQ83215.1 - 6.5e-173 575.5 0.1 8.2e-173 575.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zip PF02535.17 EAQ83215.1 - 0.23 10.4 2.4 0.48 9.3 1.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Fig1 PF12351.3 EAQ83216.1 - 3.6e-55 186.6 5.2 5.2e-55 186.1 3.6 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EAQ83216.1 - 7.8e-07 28.8 7.0 1.1e-06 28.3 4.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EAQ83216.1 - 0.00071 18.5 4.1 0.00093 18.1 2.8 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EAQ83216.1 - 0.9 9.8 4.5 0.7 10.1 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DASH_Spc34 PF08657.5 EAQ83217.1 - 7.9e-18 65.0 10.6 1.4e-15 57.6 0.4 2.3 2 1 0 2 2 2 2 DASH complex subunit Spc34 ERM PF00769.14 EAQ83217.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4140 PF13600.1 EAQ83217.1 - 1.1 9.7 4.5 2.1 8.8 3.1 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2360 PF10152.4 EAQ83217.1 - 2.1 8.5 7.7 2.4 8.4 1.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Sporozoite_P67 PF05642.6 EAQ83218.1 - 0.018 12.9 7.8 0.03 12.1 5.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1690 PF07956.6 EAQ83218.1 - 0.048 13.6 0.2 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) TFIID_20kDa PF03847.8 EAQ83219.1 - 2.7e-17 62.7 0.0 4.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A NolV PF06635.7 EAQ83219.1 - 0.044 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein NolV AAA_23 PF13476.1 EAQ83219.1 - 4.4 7.5 11.4 8.6 6.6 7.4 1.8 2 0 0 2 2 2 0 AAA domain Pex16 PF08610.5 EAQ83219.1 - 5.7 5.8 12.8 13 4.6 8.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Rpn3_C PF08375.6 EAQ83220.1 - 2.6e-24 85.4 1.4 2.6e-24 85.4 1.0 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EAQ83220.1 - 1.1e-19 70.6 0.2 6.4e-19 68.2 0.0 2.3 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 EAQ83220.1 - 0.012 15.4 0.1 0.043 13.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EAQ83221.1 - 0.00028 20.8 3.4 0.00049 20.0 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ83221.1 - 0.0031 17.3 4.9 0.0058 16.4 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAQ83221.1 - 0.009 15.6 2.5 0.018 14.7 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2384 PF09722.5 EAQ83221.1 - 0.073 12.9 0.6 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) zf-C3HC4_3 PF13920.1 EAQ83221.1 - 0.66 9.6 6.0 1 9.0 4.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Drc1-Sld2 PF11719.3 EAQ83222.1 - 6.4e-55 186.9 34.3 2.5e-53 181.7 23.8 3.2 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF320 PF03777.8 EAQ83223.1 - 7.6 6.3 14.5 0.66 9.7 0.9 3.7 2 1 1 3 3 3 0 Small secreted domain (DUF320) DNA_methylase PF00145.12 EAQ83224.1 - 2.8e-27 95.7 0.0 1.7e-26 93.1 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EAQ83224.1 - 3e-05 23.7 0.0 0.003 17.3 0.0 2.6 2 0 0 2 2 2 2 BAH domain MOZ_SAS PF01853.13 EAQ83225.1 - 2.4e-46 157.3 0.0 5.6e-46 156.1 0.0 1.6 1 1 0 1 1 1 1 MOZ/SAS family ATP-synt_C PF00137.16 EAQ83226.1 - 1.8e-10 40.5 6.7 3.6e-10 39.5 4.6 1.5 1 0 0 1 1 1 1 ATP synthase subunit C Inhibitor_I36 PF03995.8 EAQ83226.1 - 0.031 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Asp_Glu_race_2 PF14669.1 EAQ83226.1 - 0.11 11.7 0.2 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative aspartate racemase iPGM_N PF06415.8 EAQ83227.1 - 2.4e-73 246.1 0.0 3.3e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EAQ83227.1 - 1.6e-71 240.6 0.0 1.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EAQ83227.1 - 3.2e-06 26.7 0.0 6.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAQ83227.1 - 4.8e-05 22.6 0.0 0.00013 21.2 0.0 1.9 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 EAQ83227.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Med9 PF07544.8 EAQ83228.1 - 1.4e-18 66.3 0.0 2.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Mucin PF01456.12 EAQ83228.1 - 1.6 8.4 13.2 2.6 7.7 9.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TBCC PF07986.7 EAQ83229.1 - 8.6e-31 105.8 0.7 2.4e-29 101.1 0.1 2.4 2 0 0 2 2 2 1 Tubulin binding cofactor C WES_acyltransf PF03007.11 EAQ83229.1 - 0.0043 16.6 0.1 0.026 14.0 0.0 2.0 1 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3580 PF12117.3 EAQ83229.1 - 0.2 11.5 6.2 0.17 11.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) Gpi1 PF05024.10 EAQ83230.1 - 2e-65 220.0 6.1 4.4e-65 218.9 4.2 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Tom37_C PF11801.3 EAQ83230.1 - 0.013 15.3 0.3 0.071 12.9 0.6 1.8 2 0 0 2 2 2 0 Tom37 C-terminal domain DNA_pol_A_exo1 PF01612.15 EAQ83231.1 - 1.1e-40 139.0 0.2 1.7e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EAQ83231.1 - 1.4e-26 92.5 0.2 2.9e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EAQ83231.1 - 1.5e-14 53.4 0.0 6.4e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 HRDC domain Rsd_AlgQ PF04353.8 EAQ83231.1 - 0.026 14.2 0.1 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ IER PF05760.7 EAQ83231.1 - 1.6 8.5 19.9 2.8 7.8 13.8 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) Asp PF00026.18 EAQ83232.1 - 7.2e-112 373.7 0.4 8.7e-112 373.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ83232.1 - 1.5e-12 47.7 0.0 1.3e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ83232.1 - 1.5e-07 31.8 0.1 0.014 15.8 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EAQ83232.1 - 0.0008 18.9 0.0 0.0098 15.4 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EAQ83232.1 - 0.053 13.6 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Prefoldin PF02996.12 EAQ83233.1 - 5.2e-05 22.8 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit REF PF05755.7 EAQ83233.1 - 0.026 14.2 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) CRAL_TRIO PF00650.15 EAQ83234.1 - 1.2e-36 125.5 0.0 1.9e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAQ83234.1 - 1.1e-09 38.2 2.3 2.5e-09 37.1 0.2 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EAQ83234.1 - 0.0013 18.6 0.0 0.006 16.4 0.0 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 EAQ83235.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like AAA PF00004.24 EAQ83237.1 - 2e-45 154.1 0.2 6.1e-45 152.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ83237.1 - 7.8e-09 35.3 0.4 2.9e-08 33.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EAQ83237.1 - 4.8e-08 33.1 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EAQ83237.1 - 4.4e-07 30.0 0.0 1.4e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ83237.1 - 7.6e-07 29.3 0.5 0.001 19.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EAQ83237.1 - 3e-06 26.3 0.0 6.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EAQ83237.1 - 0.00016 21.5 0.2 0.00083 19.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EAQ83237.1 - 0.00036 19.6 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EAQ83237.1 - 0.00037 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ83237.1 - 0.00051 20.8 0.0 0.0023 18.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EAQ83237.1 - 0.001 18.7 0.3 0.057 13.0 0.0 2.6 1 1 0 2 2 2 1 NACHT domain TIP49 PF06068.8 EAQ83237.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EAQ83237.1 - 0.0013 17.8 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EAQ83237.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EAQ83237.1 - 0.0018 18.3 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EAQ83237.1 - 0.0026 17.4 0.0 0.0089 15.7 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EAQ83237.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EAQ83237.1 - 0.0038 17.5 0.8 0.85 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EAQ83237.1 - 0.0039 16.8 0.1 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAQ83237.1 - 0.0051 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EAQ83237.1 - 0.0052 16.4 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EAQ83237.1 - 0.0061 15.7 0.2 0.013 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EAQ83237.1 - 0.0077 15.9 0.5 0.058 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_30 PF13604.1 EAQ83237.1 - 0.0081 15.7 0.1 0.021 14.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EAQ83237.1 - 0.0092 16.2 0.0 0.026 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EAQ83237.1 - 0.0092 15.5 0.4 0.03 13.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAQ83237.1 - 0.01 15.2 0.5 0.024 14.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_Hsp90 PF03225.9 EAQ83237.1 - 0.012 13.8 0.0 0.019 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Cast PF10174.4 EAQ83237.1 - 0.013 13.6 2.2 0.023 12.8 0.9 1.6 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Bac_DnaA PF00308.13 EAQ83237.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EAQ83237.1 - 0.023 13.8 1.1 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EAQ83237.1 - 0.04 13.3 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EAQ83237.1 - 0.07 12.5 0.1 0.07 12.5 0.1 2.9 3 1 1 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.1 EAQ83237.1 - 0.084 12.9 0.1 0.37 10.8 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EAQ83237.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EAQ83237.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.3 EAQ83238.1 - 1.5e-19 70.2 0.0 3e-19 69.2 0.0 1.5 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Y_phosphatase PF00102.22 EAQ83239.1 - 2e-35 122.2 0.0 4.7e-35 121.0 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EAQ83239.1 - 0.0024 17.4 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EAQ83239.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EAQ83239.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RCC1 PF00415.13 EAQ83240.1 - 6.5e-30 103.1 11.7 5.2e-06 26.5 0.0 7.6 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAQ83240.1 - 2.2e-12 46.2 22.5 2.9e-08 33.0 0.0 6.7 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 EAQ83241.1 - 4.6e-20 71.9 0.1 7.9e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 Sec34-like family CENP-B_dimeris PF09026.5 EAQ83241.1 - 1.5 9.0 10.4 4.8 7.4 7.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDO_I PF05995.7 EAQ83242.1 - 0.00025 20.2 0.1 0.00055 19.1 0.1 1.5 1 0 0 1 1 1 1 Cysteine dioxygenase type I VCBS PF13517.1 EAQ83248.1 - 3.5e-31 107.3 32.3 8.5e-15 54.8 1.0 7.9 2 2 6 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAQ83248.1 - 1.6e-16 59.4 30.7 0.0012 18.4 0.6 7.3 7 0 0 7 7 7 6 FG-GAP repeat Lipase_GDSL PF00657.17 EAQ83248.1 - 1.5e-14 54.4 2.1 4.3e-13 49.6 0.1 2.7 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAQ83248.1 - 5.2e-13 49.5 0.3 1e-12 48.5 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 EAQ83248.1 - 2e-05 24.1 12.0 0.84 9.0 0.0 6.1 5 1 2 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 EAQ83248.1 - 0.00026 20.7 0.1 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.22 EAQ83249.1 - 8.2e-32 110.2 0.0 1.9e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ83249.1 - 2.2e-21 75.6 0.0 3e-20 72.0 0.0 2.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ83249.1 - 2.5e-09 37.4 0.1 1.1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family APG6 PF04111.7 EAQ83249.1 - 0.12 11.3 2.7 0.24 10.4 1.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 EAQ83249.1 - 0.13 12.1 1.0 0.41 10.5 0.7 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 EAQ83249.1 - 0.18 10.1 0.6 0.36 9.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 EAQ83249.1 - 0.29 11.5 8.2 0.65 10.4 5.0 2.2 1 1 0 1 1 1 0 SlyX DUF883 PF05957.8 EAQ83249.1 - 4.2 7.8 14.4 0.79 10.1 0.6 4.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ADIP PF11559.3 EAQ83249.1 - 5.4 6.8 12.2 0.28 11.0 4.4 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mito_carr PF00153.22 EAQ83251.1 - 6e-58 192.5 2.0 2.7e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.8 EAQ83252.1 - 1.3e-86 291.1 0.0 2.5e-86 290.2 0.0 1.4 1 1 0 1 1 1 1 RINT-1 / TIP-1 family DUF4164 PF13747.1 EAQ83252.1 - 0.013 15.6 4.2 0.025 14.7 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.3 EAQ83252.1 - 0.13 12.1 2.0 0.42 10.4 1.4 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF155 PF02582.9 EAQ83253.1 - 3.3e-37 128.0 0.0 5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SHMT PF00464.14 EAQ83255.1 - 4.6e-207 687.1 0.0 5.8e-207 686.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EAQ83255.1 - 0.00028 19.9 0.0 0.00067 18.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EAQ83255.1 - 0.00054 18.7 0.0 0.00079 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAQ83255.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase KKLCAg1 PF15204.1 EAQ83255.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Bromodomain PF00439.20 EAQ83256.1 - 2.2e-18 65.9 0.1 5.9e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EAQ83256.1 - 4.4e-09 35.9 0.0 3.5e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 EAQ83257.1 - 3.2e-15 56.2 1.8 4.2e-15 55.8 1.2 1.1 1 0 0 1 1 1 1 VanZ like family NAD_binding_6 PF08030.7 EAQ83258.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EAQ83258.1 - 5.3e-17 62.0 5.4 5.3e-17 62.0 3.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EAQ83258.1 - 7.6e-06 26.4 0.1 0.098 13.2 0.0 2.5 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EAQ83258.1 - 1e-05 25.3 0.0 5.1e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain Cytochrom_B_N PF00033.14 EAQ83258.1 - 0.099 11.9 6.2 2.2 7.5 1.6 2.4 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Pyr_redox_3 PF13738.1 EAQ83259.1 - 2e-15 57.4 0.1 7.3e-15 55.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ83259.1 - 6.8e-12 44.3 0.0 1.2e-11 43.5 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAQ83259.1 - 8.2e-08 32.3 0.0 9.8e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ83259.1 - 6.5e-06 25.2 0.0 3.2e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAQ83259.1 - 6.7e-05 22.8 0.0 0.0003 20.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ83259.1 - 0.0013 17.7 0.2 1.3 7.8 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAQ83259.1 - 0.0029 17.3 0.4 0.072 12.8 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding Imm49 PF15660.1 EAQ83259.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 49 Osmo_MPGsynth PF09488.5 EAQ83259.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) TPR_12 PF13424.1 EAQ83260.1 - 5.1e-71 234.6 0.0 1.3e-17 63.5 0.0 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ83260.1 - 6.3e-67 219.7 0.0 1.9e-12 46.6 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ83260.1 - 4.7e-23 79.0 0.1 0.0016 18.0 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ83260.1 - 8.4e-14 50.3 0.1 0.35 10.9 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ83260.1 - 2.7e-12 45.8 1.2 0.26 11.5 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ83260.1 - 9.2e-12 44.0 0.0 0.77 9.4 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ83260.1 - 3.1e-11 42.7 0.0 0.00059 19.4 0.0 3.9 2 2 1 3 3 3 3 TPR repeat TPR_14 PF13428.1 EAQ83260.1 - 8.6e-11 41.4 1.0 3.9 8.3 0.0 7.0 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ83260.1 - 4.4e-09 35.9 0.0 10 6.9 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ83260.1 - 1.6e-08 34.9 0.0 0.0036 17.9 0.0 4.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ83260.1 - 2.6e-08 33.0 0.0 3.9 7.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ83260.1 - 6.1e-08 32.8 0.0 0.11 12.8 0.0 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ83260.1 - 1.4e-07 30.7 0.0 0.0016 17.3 0.0 2.4 1 1 1 2 2 2 2 NB-ARC domain TPR_6 PF13174.1 EAQ83260.1 - 4.3e-06 26.8 2.4 28 5.4 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EAQ83260.1 - 9.8e-06 25.6 0.0 0.073 13.2 0.0 3.5 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 PIF1 PF05970.9 EAQ83260.1 - 1.3e-05 24.3 0.2 0.00036 19.6 0.0 2.3 2 1 0 2 2 2 1 PIF1-like helicase TPR_5 PF12688.2 EAQ83260.1 - 2.7e-05 24.1 0.0 8.9 6.3 0.0 4.5 1 1 3 4 4 4 0 Tetratrico peptide repeat PPR PF01535.15 EAQ83260.1 - 0.00013 21.7 1.1 18 5.5 0.0 5.3 5 0 0 5 5 5 0 PPR repeat DUF4074 PF13293.1 EAQ83260.1 - 0.00036 20.6 0.2 25 5.1 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4074) Herpes_Helicase PF02689.9 EAQ83260.1 - 0.0011 16.8 0.0 0.0017 16.2 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ83260.1 - 0.0012 18.9 0.0 0.0034 17.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TPR_3 PF07720.7 EAQ83260.1 - 0.0019 17.9 0.0 11 5.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EAQ83260.1 - 0.0025 17.7 1.2 5.8 6.7 0.2 3.5 1 1 3 4 4 4 0 Rabaptin-like protein AAA_25 PF13481.1 EAQ83260.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Granin PF01271.12 EAQ83260.1 - 0.076 11.7 3.3 2 7.0 0.2 2.7 1 1 2 3 3 3 0 Granin (chromogranin or secretogranin) AAA_17 PF13207.1 EAQ83260.1 - 0.12 13.1 0.0 0.32 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mannosyl_trans3 PF11051.3 EAQ83261.1 - 4.4e-74 249.2 0.0 1.3e-73 247.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EAQ83261.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 Chorion_2 PF03964.10 EAQ83261.1 - 0.46 11.0 6.2 0.73 10.4 1.6 2.9 3 0 0 3 3 3 0 Chorion family 2 DUF2360 PF10152.4 EAQ83261.1 - 1.9 8.7 9.5 0.088 13.0 2.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_S10 PF00450.17 EAQ83262.1 - 2.3e-63 214.8 0.0 2.5e-55 188.3 0.0 2.5 2 1 0 2 2 2 2 Serine carboxypeptidase RTA1 PF04479.8 EAQ83263.1 - 7.9e-35 120.3 2.1 1.3e-34 119.6 1.5 1.2 1 0 0 1 1 1 1 RTA1 like protein RRM_1 PF00076.17 EAQ83264.1 - 1.4e-08 34.2 0.0 2.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ83264.1 - 5.3e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ83264.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 EAQ83265.1 - 0.0022 17.7 1.3 0.0026 17.5 0.9 1.3 1 0 0 1 1 1 1 RF-1 domain K-box PF01486.12 EAQ83265.1 - 0.19 11.5 4.1 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 K-box region GNAT_acetyltr_2 PF13718.1 EAQ83266.1 - 6.2e-81 270.4 0.0 9.8e-81 269.7 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EAQ83266.1 - 2.7e-65 219.3 0.0 1.1e-64 217.2 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EAQ83266.1 - 2.6e-39 132.7 0.0 6e-39 131.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EAQ83266.1 - 1.9e-28 98.5 0.1 5.6e-28 97.0 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EAQ83266.1 - 0.0012 18.9 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.1 EAQ83266.1 - 0.0024 17.9 0.0 0.0073 16.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EAQ83267.1 - 3.6e-50 170.5 0.0 4.5e-43 147.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83267.1 - 2.1e-20 72.9 0.0 6.3e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ83267.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ83267.1 - 0.0002 21.2 0.1 0.00031 20.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAQ83267.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 EAQ83267.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PAP2 PF01569.16 EAQ83268.1 - 2.2e-11 43.5 12.7 7.4e-11 41.8 8.4 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EAQ83268.1 - 3.4e-07 29.9 7.7 1.1e-06 28.2 5.4 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EAQ83268.1 - 2.7 8.3 7.1 1.6 9.0 1.1 2.7 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Clp1 PF06807.9 EAQ83270.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Ribosomal_L34e PF01199.13 EAQ83270.1 - 0.14 12.4 0.3 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L34e Glyco_hydro_61 PF03443.9 EAQ83271.1 - 1.5e-15 57.5 0.1 2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EAQ83273.1 - 1.1e-19 70.4 14.6 1.1e-19 70.4 10.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 EAQ83273.1 - 0.21 11.7 2.2 0.88 9.7 0.4 2.8 3 0 0 3 3 3 0 PepSY-associated TM helix Glyco_hydro_3 PF00933.16 EAQ83274.1 - 1.1e-68 231.3 0.0 2.7e-61 207.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ83274.1 - 1.6e-54 184.8 0.7 1.9e-54 184.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ83274.1 - 2.5e-14 52.9 0.0 4.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lgl_C PF08596.5 EAQ83275.1 - 3.4e-65 220.0 0.0 8.3e-65 218.7 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EAQ83275.1 - 0.00014 21.6 2.6 0.073 12.9 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EAQ83275.1 - 0.0063 15.9 0.2 0.94 8.8 0.0 2.6 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EAQ83275.1 - 0.028 13.1 0.0 5.9 5.5 0.0 3.3 4 0 0 4 4 4 0 Nup133 N terminal like PAZ PF02170.17 EAQ83276.1 - 1.3e-12 47.1 0.2 3.1e-12 45.9 0.2 1.6 1 1 0 1 1 1 1 PAZ domain Piwi PF02171.12 EAQ83276.1 - 3.6e-07 29.4 0.1 7.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EAQ83276.1 - 0.0003 20.1 0.1 0.00057 19.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 EAQ83277.1 - 1.7e-88 297.0 0.6 1e-83 281.3 0.0 3.4 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EAQ83277.1 - 0.0002 21.9 0.0 0.0027 18.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ83277.1 - 0.00083 19.7 0.5 0.031 14.9 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 EAQ83277.1 - 0.017 14.8 0.1 0.3 10.8 0.1 2.6 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat ASF1_hist_chap PF04729.8 EAQ83278.1 - 2.8e-67 225.1 0.0 4.1e-67 224.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Cwf_Cwc_15 PF04889.7 EAQ83278.1 - 0.76 9.4 4.1 0.87 9.2 2.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nrap PF03813.9 EAQ83279.1 - 0 1105.3 0.0 3.2e-182 607.5 0.0 2.0 1 1 1 2 2 2 2 Nrap protein TPR_11 PF13414.1 EAQ83280.1 - 6.8e-43 144.1 37.3 6.2e-07 28.9 0.0 11.6 9 3 4 13 13 13 11 TPR repeat TPR_16 PF13432.1 EAQ83280.1 - 1.9e-36 123.9 62.1 3.5e-08 33.9 0.6 13.3 11 3 2 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ83280.1 - 8.7e-32 106.4 48.3 0.0012 18.6 0.0 15.7 16 0 0 16 16 15 10 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ83280.1 - 4e-28 95.3 49.9 0.00029 21.2 0.1 15.9 13 4 3 16 16 15 8 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ83280.1 - 9.8e-28 94.6 26.1 0.00012 21.4 0.0 13.9 13 1 0 13 13 13 7 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ83280.1 - 1.3e-24 84.2 11.4 0.17 12.1 0.0 14.1 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ83280.1 - 2.1e-18 66.4 42.4 6.2e-06 26.4 0.9 11.6 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ83280.1 - 4.6e-17 61.7 54.4 2.2e-05 24.2 0.0 12.8 8 5 8 16 16 16 7 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ83280.1 - 3.2e-15 54.6 28.1 0.033 13.9 0.0 13.1 12 2 2 14 14 14 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ83280.1 - 1.1e-12 46.6 29.7 0.013 15.2 0.0 13.8 14 1 0 14 14 14 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ83280.1 - 2.6e-09 36.9 23.6 0.66 10.5 0.0 12.4 14 0 0 14 14 12 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ83280.1 - 1e-06 28.7 18.1 0.4 10.8 0.0 7.5 7 2 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EAQ83280.1 - 0.00076 19.3 0.5 13 5.7 0.0 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EAQ83280.1 - 0.0072 16.1 25.6 0.017 14.9 0.1 7.9 8 1 0 8 8 8 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EAQ83280.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region Apc5 PF12862.2 EAQ83280.1 - 0.17 11.7 15.9 0.42 10.4 0.8 6.1 8 0 0 8 8 7 0 Anaphase-promoting complex subunit 5 PPTA PF01239.17 EAQ83280.1 - 0.19 11.1 0.4 25 4.4 0.0 3.8 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat ChAPs PF09295.5 EAQ83280.1 - 0.39 9.4 1.9 22 3.6 0.0 3.9 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 EAQ83280.1 - 5.4 7.7 38.5 2.1 9.0 3.4 9.3 10 0 0 10 10 7 0 Tetratricopeptide repeat DUF1767 PF08585.7 EAQ83281.1 - 4.9e-06 26.7 0.0 7.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) CPSF100_C PF13299.1 EAQ83283.1 - 2.9e-36 125.1 0.0 5.2e-35 121.0 0.0 2.8 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EAQ83283.1 - 9.4e-27 93.4 0.0 2.9e-26 91.8 0.0 1.9 1 1 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EAQ83283.1 - 4.6e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EAQ83283.1 - 0.0003 20.4 0.3 0.0011 18.6 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAQ83283.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sec23_trunk PF04811.10 EAQ83284.1 - 1.7e-52 178.1 0.0 3.9e-52 177.0 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EAQ83284.1 - 1.6e-21 75.7 0.0 2.8e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EAQ83284.1 - 3.2e-18 66.0 0.0 5.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAQ83284.1 - 5e-17 61.1 3.4 1e-16 60.1 2.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EAQ83284.1 - 1.1e-06 28.2 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.4 EAQ83285.1 - 1.6e-12 47.6 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) tRNA-synt_2 PF00152.15 EAQ83286.1 - 3.8e-17 62.0 0.0 5.2e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAQ83286.1 - 0.0058 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FRG1 PF06229.7 EAQ83286.1 - 0.096 12.1 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 FRG1-like family Gti1_Pac2 PF09729.4 EAQ83288.1 - 8.7e-39 133.0 0.4 5.6e-38 130.4 0.0 2.1 2 0 0 2 2 2 1 Gti1/Pac2 family Coagulin PF02035.10 EAQ83289.1 - 0.073 12.7 0.2 0.084 12.5 0.1 1.1 1 0 0 1 1 1 0 Coagulin Linker_histone PF00538.14 EAQ83290.1 - 2.1e-16 59.7 1.7 4.2e-16 58.8 1.2 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family GlutR_dimer PF00745.15 EAQ83290.1 - 0.0083 16.0 0.5 0.019 14.9 0.3 1.7 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain RdRP_2 PF00978.16 EAQ83290.1 - 0.21 10.2 3.9 0.27 9.8 2.7 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase ELYS PF13934.1 EAQ83292.1 - 3.2e-63 213.4 0.0 4e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EAQ83293.1 - 4.1e-79 264.8 0.1 2.1e-78 262.5 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAQ83293.1 - 2.2e-26 92.1 0.0 8.1e-26 90.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EAQ83293.1 - 7.6e-12 45.7 5.5 4.5e-05 23.5 0.4 3.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EAQ83293.1 - 0.00029 20.2 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EAQ83293.1 - 0.0013 17.9 0.8 0.0013 17.9 0.5 4.7 2 2 2 5 5 5 1 Reovirus sigma C capsid protein Laminin_II PF06009.7 EAQ83293.1 - 0.0022 17.7 2.2 0.0022 17.7 1.6 7.7 4 2 4 8 8 8 2 Laminin Domain II CVNH PF08881.5 EAQ83293.1 - 0.0023 18.1 0.1 0.0023 18.1 0.1 4.3 5 0 0 5 5 5 1 CVNH domain AAA_13 PF13166.1 EAQ83293.1 - 0.04 12.3 94.7 0.025 13.0 19.0 5.5 3 2 1 5 5 5 0 AAA domain TPR_MLP1_2 PF07926.7 EAQ83293.1 - 1.1 8.9 109.2 0.01 15.5 18.4 7.8 3 2 5 8 8 8 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EAQ83293.1 - 5.2 6.8 44.5 0.098 12.4 2.4 6.7 4 2 5 9 9 9 0 Protein of unknown function (DUF1664) RPAP1_C PF08620.5 EAQ83294.1 - 7.6e-29 99.3 0.0 1.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EAQ83294.1 - 9.9e-15 53.8 0.6 1.8e-14 53.0 0.4 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.5 EAQ83295.1 - 5.8e-14 51.7 0.6 1e-13 50.8 0.4 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain MFS_1 PF07690.11 EAQ83296.1 - 3.2e-34 118.1 40.7 2.5e-33 115.2 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ83296.1 - 1e-08 34.2 9.0 1e-08 34.2 6.2 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ83296.1 - 5.4e-05 21.5 3.2 9.8e-05 20.7 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RasGAP PF00616.14 EAQ83299.1 - 7.2e-55 185.7 0.8 4e-54 183.2 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EAQ83299.1 - 1e-28 99.7 4.3 1e-28 99.7 3.0 2.4 2 0 0 2 2 2 1 RasGAP C-terminus MeMO_Hyd_G PF02964.11 EAQ83299.1 - 0.13 12.1 2.0 0.11 12.4 0.2 1.8 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain MARVEL PF01284.18 EAQ83300.1 - 0.0039 17.0 16.6 0.0056 16.5 11.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Ycf9 PF01737.12 EAQ83300.1 - 2.9 7.4 14.5 0.65 9.4 1.6 2.9 2 1 1 3 3 3 0 YCF9 PUF PF00806.14 EAQ83303.1 - 5.7e-11 41.2 0.0 0.46 10.0 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat GAGA_bind PF06217.7 EAQ83303.1 - 6.8 6.5 17.9 0.11 12.3 6.5 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF2633 PF11119.3 EAQ83304.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) HAD_2 PF13419.1 EAQ83305.1 - 6.1e-17 62.4 0.0 1.7e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ83305.1 - 0.052 13.9 0.0 0.24 11.7 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HNH PF01844.18 EAQ83306.1 - 0.00015 21.5 2.0 0.00029 20.6 1.4 1.5 1 0 0 1 1 1 1 HNH endonuclease Anth_synt_I_N PF04715.8 EAQ83307.1 - 0.13 12.3 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region AMMECR1 PF01871.12 EAQ83309.1 - 2.5e-28 98.3 0.0 5.4e-28 97.2 0.0 1.4 1 1 1 2 2 2 1 AMMECR1 Ras PF00071.17 EAQ83310.1 - 5.4e-36 123.4 0.0 5.1e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAQ83310.1 - 2.3e-10 41.0 0.0 4.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAQ83310.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.13 EAQ83310.1 - 0.27 10.7 0.0 0.43 10.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pyridoxal_deC PF00282.14 EAQ83312.1 - 2.5e-46 157.8 0.0 6.6e-45 153.1 0.0 2.3 2 1 1 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EAQ83312.1 - 4.5e-05 22.3 0.0 5.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAQ83312.1 - 0.00047 19.3 0.0 0.00094 18.4 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EAQ83312.1 - 0.058 11.8 0.0 0.079 11.4 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Thi4 PF01946.12 EAQ83313.1 - 4.3e-103 343.3 0.3 5.3e-103 343.0 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EAQ83313.1 - 2.1e-07 30.2 1.4 3.8e-06 26.0 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ83313.1 - 9e-05 22.4 1.1 0.00024 21.0 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ83313.1 - 0.00019 20.4 0.3 0.00046 19.2 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EAQ83313.1 - 0.00042 20.1 0.2 0.0014 18.4 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EAQ83313.1 - 0.00059 19.7 0.1 0.00097 19.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ83313.1 - 0.0017 17.3 1.9 0.014 14.2 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EAQ83313.1 - 0.0023 18.0 0.5 0.0035 17.4 0.3 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ83313.1 - 0.0055 15.8 0.5 0.0099 15.0 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ83313.1 - 0.09 13.1 1.2 0.65 10.4 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ83313.1 - 0.094 11.1 0.5 0.15 10.4 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EAQ83313.1 - 0.11 11.0 0.3 0.16 10.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF4243 PF14027.1 EAQ83315.1 - 1.8e-17 63.7 0.0 2.4e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) LCCL PF03815.14 EAQ83316.1 - 4.2e-23 81.1 0.0 6e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 LCCL domain MAM33 PF02330.11 EAQ83317.1 - 2.9e-30 105.5 2.0 7.5e-30 104.2 1.4 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 EAQ83318.1 - 1.1e-28 99.7 0.1 1.2e-28 99.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) RRP7 PF12923.2 EAQ83318.1 - 0.07 13.1 1.1 0.12 12.4 0.7 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) SURF6 PF04935.7 EAQ83319.1 - 1.2e-47 161.9 45.5 1.2e-47 161.9 31.6 4.3 1 1 2 3 3 3 1 Surfeit locus protein 6 XPG_I PF00867.13 EAQ83319.1 - 1.4e-24 85.9 0.0 6.1e-24 83.8 0.0 2.2 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAQ83319.1 - 1.1e-23 83.3 0.1 5.4e-23 81.1 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain RRP14 PF15459.1 EAQ83319.1 - 6.2e-21 74.2 1.2 6.2e-21 74.2 0.8 7.0 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 5_3_exonuc PF01367.15 EAQ83319.1 - 0.013 15.7 0.0 0.013 15.7 0.0 2.7 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold GPP34 PF05719.6 EAQ83320.1 - 3.8e-65 219.8 0.1 5e-65 219.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Oxysterol_BP PF01237.13 EAQ83321.1 - 4.9e-48 163.4 2.3 2.6e-23 82.0 0.0 3.0 2 1 1 3 3 3 3 Oxysterol-binding protein CP2 PF04516.10 EAQ83323.1 - 3.7e-86 288.0 0.0 5.3e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 EAQ83323.1 - 0.0091 14.5 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Tektin family Phage_G PF02306.10 EAQ83323.1 - 0.015 14.9 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) TMF_DNA_bd PF12329.3 EAQ83323.1 - 0.091 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding eIF2A PF08662.6 EAQ83327.1 - 6.4e-30 104.3 0.0 2e-24 86.4 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EAQ83327.1 - 0.002 17.9 0.2 1.3 9.0 0.1 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat CDV3 PF15359.1 EAQ83327.1 - 0.042 13.9 0.2 0.042 13.9 0.1 2.6 3 1 0 3 3 3 0 Carnitine deficiency-associated protein 3 DUF1510 PF07423.6 EAQ83329.1 - 0.044 13.1 6.9 0.047 13.0 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop53 PF07767.6 EAQ83329.1 - 0.058 12.3 11.7 0.066 12.2 8.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BSP_II PF05432.6 EAQ83329.1 - 0.24 10.6 9.8 0.28 10.4 6.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Spt5_N PF11942.3 EAQ83329.1 - 0.29 11.7 12.0 0.44 11.2 8.3 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PRP21_like_P PF12230.3 EAQ83329.1 - 0.32 10.4 7.9 0.39 10.1 5.5 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DUF3381 PF11861.3 EAQ83329.1 - 0.43 10.0 12.7 0.56 9.6 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) EBV-NA3 PF05009.7 EAQ83329.1 - 1.2 8.3 4.8 1.3 8.2 3.3 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CobT PF06213.7 EAQ83329.1 - 1.2 8.2 14.3 1.3 8.1 9.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EAQ83329.1 - 1.2 6.9 14.8 1.3 6.8 10.3 1.0 1 0 0 1 1 1 0 Nop14-like family HSP90 PF00183.13 EAQ83329.1 - 1.5 7.1 10.6 1.7 6.9 7.4 1.0 1 0 0 1 1 1 0 Hsp90 protein Pox_RNA_Pol_19 PF05320.7 EAQ83329.1 - 1.5 8.5 8.1 1.8 8.2 5.6 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 EAQ83329.1 - 1.5 6.7 14.5 1.5 6.7 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EAQ83329.1 - 1.6 8.5 4.9 1.6 8.4 3.4 1.1 1 0 0 1 1 1 0 DDHD domain Trypan_PARP PF05887.6 EAQ83329.1 - 2.8 7.7 8.3 3.3 7.5 5.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 EAQ83329.1 - 6.8 5.8 7.7 7.7 5.6 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein TLP-20 PF06088.6 EAQ83329.1 - 9.4 5.8 7.6 12 5.5 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) GTP_EFTU PF00009.22 EAQ83331.1 - 1.5e-40 138.6 1.8 1.2e-39 135.6 1.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EAQ83331.1 - 8.8e-25 86.7 0.3 1.9e-24 85.6 0.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EAQ83331.1 - 4.9e-14 52.1 3.8 1.1e-07 31.8 0.1 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EAQ83331.1 - 5.5e-08 32.3 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EAQ83331.1 - 8.9e-08 32.0 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ83331.1 - 3e-06 27.7 0.1 6.7e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ83331.1 - 9.4e-06 24.9 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EAQ83331.1 - 2.1e-05 24.0 0.1 5.4e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EAQ83331.1 - 0.00012 21.3 0.1 0.00024 20.3 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EAQ83331.1 - 0.0015 17.8 0.2 0.0035 16.5 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EAQ83331.1 - 0.017 13.8 0.2 0.058 12.1 0.1 1.8 1 1 0 1 1 1 0 ArgK protein GTP_EFTU_D4 PF14578.1 EAQ83331.1 - 0.023 14.3 3.5 0.51 10.0 0.5 2.6 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 EAQ83331.1 - 0.12 12.1 3.5 3.8 7.3 0.0 3.5 2 1 1 3 3 3 0 Dynamin family DUF367 PF04034.8 EAQ83332.1 - 3.1e-45 152.8 0.0 4.4e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EAQ83332.1 - 6.3e-11 41.6 0.4 1.4e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BSP_II PF05432.6 EAQ83332.1 - 0.15 11.3 15.9 0.012 14.9 5.4 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.7 EAQ83332.1 - 8.7 5.5 18.2 17 4.5 12.6 1.4 1 0 0 1 1 1 0 SDA1 VHS PF00790.14 EAQ83333.1 - 8.9e-44 148.5 0.0 1e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 VHS domain RasGEF_N PF00618.15 EAQ83333.1 - 0.1 12.6 0.0 0.57 10.3 0.0 1.9 1 1 1 2 2 2 0 RasGEF N-terminal motif DUF676 PF05057.9 EAQ83334.1 - 0.004 16.4 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EAQ83334.1 - 0.0095 15.5 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Dot_icm_IcmQ PF09475.5 EAQ83334.1 - 0.29 10.3 0.0 0.53 9.4 0.0 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) FHA PF00498.21 EAQ83335.1 - 5.4e-15 55.2 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 EAQ83335.1 - 8.7 4.6 21.6 12 4.2 15.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IBR PF01485.16 EAQ83336.1 - 1.1e-21 76.3 46.4 7.8e-12 44.8 4.9 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EAQ83336.1 - 2.7e-05 24.1 7.8 2.7e-05 24.1 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ83336.1 - 3.4e-05 23.4 42.2 0.00036 20.1 3.6 4.6 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ83336.1 - 0.0001 22.0 42.4 0.00013 21.7 3.6 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EAQ83336.1 - 1.3 8.8 42.7 0.053 13.2 5.5 3.8 3 1 0 3 3 3 0 zinc-RING finger domain CoA_trans PF01144.18 EAQ83337.1 - 5.2e-63 212.1 0.3 5.7e-52 176.0 0.0 3.0 2 1 1 3 3 3 3 Coenzyme A transferase Redoxin PF08534.5 EAQ83338.1 - 1.7e-17 63.2 0.1 8.2e-10 38.3 0.0 2.1 1 1 1 2 2 2 2 Redoxin DASH_Dam1 PF08653.5 EAQ83339.1 - 9.8e-28 95.7 1.0 1.4e-27 95.1 0.7 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 EAQ83340.1 - 2.4e-44 150.6 1.3 2.6e-44 150.5 0.2 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAQ83340.1 - 7.7e-15 54.7 0.2 2.9e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EAQ83340.1 - 6e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 EAQ83341.1 - 1e-09 38.8 0.0 1.8e-09 37.9 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EAQ83341.1 - 0.00012 22.2 0.2 0.0002 21.5 0.0 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EAQ83341.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 SprT-like PF10263.4 EAQ83342.1 - 2.2e-48 163.9 2.4 4.5e-48 162.8 1.7 1.5 1 0 0 1 1 1 1 SprT-like family DUF3439 PF11921.3 EAQ83342.1 - 0.015 15.0 6.1 0.028 14.1 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_MA_2 PF13485.1 EAQ83342.1 - 0.098 12.6 0.5 0.25 11.3 0.4 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily DUF4359 PF14271.1 EAQ83342.1 - 0.17 12.2 2.3 2.3 8.6 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4359) SSP160 PF06933.6 EAQ83342.1 - 0.24 9.3 9.5 0.35 8.7 6.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Host_attach PF10116.4 EAQ83342.1 - 2 8.6 7.0 0.3 11.2 0.7 2.4 2 0 0 2 2 2 0 Protein required for attachment to host cells Glucan_synthase PF02364.10 EAQ83343.1 - 0 1173.3 8.0 1e-222 741.4 1.8 2.3 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EAQ83343.1 - 1.2e-40 138.0 0.3 2.7e-40 136.9 0.2 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 FAM176 PF14851.1 EAQ83343.1 - 8.5 6.0 5.8 2.8 7.6 1.0 2.2 2 0 0 2 2 2 0 FAM176 family Aminotran_1_2 PF00155.16 EAQ83344.1 - 3.8e-36 124.8 0.0 4.8e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II BtpA PF03437.10 EAQ83344.1 - 0.0083 15.4 0.2 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 BtpA family Cys_Met_Meta_PP PF01053.15 EAQ83344.1 - 0.024 12.9 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EAQ83344.1 - 0.12 10.9 0.0 0.71 8.3 0.0 2.2 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain RVT_1 PF00078.22 EAQ83345.1 - 0.00046 19.6 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Xan_ur_permease PF00860.15 EAQ83346.1 - 2e-64 217.5 32.1 3.3e-63 213.4 22.3 2.0 1 1 0 1 1 1 1 Permease family DUF3082 PF11282.3 EAQ83347.1 - 0.018 15.0 3.9 0.28 11.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) HemY_N PF07219.8 EAQ83347.1 - 0.041 13.4 4.1 2.3 7.8 1.3 2.5 2 0 0 2 2 2 0 HemY protein N-terminus MARVEL PF01284.18 EAQ83347.1 - 0.13 12.1 20.1 0.18 11.6 13.9 1.2 1 0 0 1 1 1 0 Membrane-associating domain IncA PF04156.9 EAQ83347.1 - 0.89 9.1 3.9 1.5 8.3 2.7 1.3 1 0 0 1 1 1 0 IncA protein 7TMR-DISM_7TM PF07695.6 EAQ83347.1 - 3.4 7.2 20.2 2.4 7.7 9.6 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Myc_target_1 PF15179.1 EAQ83347.1 - 9 5.8 8.8 4.1 6.9 1.1 2.1 2 0 0 2 2 2 0 Myc target protein 1 PIF1 PF05970.9 EAQ83351.1 - 4.5e-22 78.5 1.2 9.1e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ83351.1 - 4.3e-11 42.8 0.0 0.00051 20.1 0.0 3.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EAQ83351.1 - 3.7e-06 26.6 0.2 9.4e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain HA PF03457.9 EAQ83351.1 - 0.025 14.7 5.1 0.077 13.1 0.0 3.3 3 0 0 3 3 3 0 Helicase associated domain Ank_2 PF12796.2 EAQ83352.1 - 2.8e-163 530.7 32.4 1.2e-23 83.1 0.2 5.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ83352.1 - 1.3e-84 274.0 24.9 1.2e-06 28.0 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EAQ83352.1 - 1.7e-61 203.5 5.3 5.9e-08 33.0 0.0 11.3 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ83352.1 - 3.2e-52 173.3 11.4 2.9e-06 27.3 0.1 11.7 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ83352.1 - 7.3e-45 146.4 5.8 0.024 14.8 0.0 11.9 11 0 0 11 11 11 10 Ankyrin repeat NACHT PF05729.7 EAQ83352.1 - 1.1e-10 41.4 0.2 2.6e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.15 EAQ83352.1 - 1.7e-10 40.3 1.0 1.6e-09 37.1 0.4 2.7 2 1 0 2 2 2 1 Phosphorylase superfamily AAA_16 PF13191.1 EAQ83352.1 - 6.3e-08 32.8 5.9 9.1e-07 29.0 0.5 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAQ83352.1 - 0.00086 19.4 0.0 0.0033 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAQ83352.1 - 0.0014 17.5 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EAQ83352.1 - 0.004 17.0 0.0 0.3 10.9 0.0 3.4 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ83352.1 - 0.0046 16.6 0.0 0.0094 15.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase CoA_trans PF01144.18 EAQ83354.1 - 1.3e-84 282.7 1.9 4.7e-42 143.6 0.1 2.8 2 1 1 3 3 3 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EAQ83354.1 - 0.00021 20.9 0.2 0.00048 19.8 0.2 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Zn_clus PF00172.13 EAQ83356.1 - 0.0014 18.4 8.0 0.0038 17.0 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_V PF00488.16 EAQ83357.1 - 1.4e-80 270.1 0.0 2.8e-80 269.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAQ83357.1 - 4.4e-49 167.0 0.0 7.7e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EAQ83357.1 - 1.1e-33 115.6 0.0 3.2e-33 114.1 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EAQ83357.1 - 1.8e-14 53.9 0.0 6.2e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EAQ83357.1 - 4.1e-12 46.1 0.7 8.5e-12 45.1 0.5 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EAQ83357.1 - 0.0017 18.7 2.4 0.0037 17.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EAQ83357.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EAQ83357.1 - 0.064 13.2 1.6 0.081 12.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain DUF1948 PF09185.5 EAQ83358.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Totivirus_coat PF05518.6 EAQ83359.1 - 3.1 5.5 9.8 4.6 4.9 6.8 1.3 1 0 0 1 1 1 0 Totivirus coat protein APH PF01636.18 EAQ83361.1 - 4.2e-08 33.2 0.0 1.2e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ83361.1 - 8.6e-06 25.4 0.1 2.2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EAQ83361.1 - 0.066 12.3 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain DUF1593 PF07632.6 EAQ83361.1 - 0.071 12.4 0.0 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) zf-MYND PF01753.13 EAQ83362.1 - 2.7e-09 36.7 4.2 2.7e-09 36.7 2.9 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EAQ83362.1 - 0.0043 16.8 6.7 0.021 14.6 2.2 2.9 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF4611 PF15387.1 EAQ83362.1 - 0.17 12.0 1.3 0.33 11.1 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HET PF06985.6 EAQ83363.1 - 5.1e-30 104.4 0.0 7.6e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.19 EAQ83364.1 - 3e-22 79.1 0.1 4.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Tyrosinase PF00264.15 EAQ83365.1 - 1.9e-45 155.7 0.0 2.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Dimer_Tnp_hAT PF05699.9 EAQ83366.1 - 3.7e-17 61.7 0.2 8e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MULE PF10551.4 EAQ83367.1 - 1.2e-11 44.5 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ83367.1 - 0.0095 16.4 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.13 EAQ83367.1 - 0.019 13.5 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family SGL PF08450.7 EAQ83369.1 - 0.0065 15.8 0.1 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EAQ83369.1 - 0.0086 15.1 0.2 0.06 12.4 0.2 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GSDH PF07995.6 EAQ83369.1 - 0.017 14.2 3.3 0.82 8.6 1.7 2.7 1 1 0 2 2 2 0 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EAQ83369.1 - 0.025 14.5 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 NHL repeat SBBP PF06739.6 EAQ83369.1 - 0.061 13.1 0.4 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Beta-propeller repeat MFS_1 PF07690.11 EAQ83370.1 - 7.7e-32 110.3 51.8 5e-20 71.5 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ83370.1 - 3.1e-14 52.4 31.7 1.5e-08 33.7 9.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EAQ83370.1 - 6.8e-06 24.7 22.4 1.1e-05 24.0 15.1 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 EAQ83370.1 - 0.012 15.3 5.5 0.14 12.0 0.1 3.2 3 1 0 3 3 3 0 MFS_1 like family Diphthamide_syn PF01866.12 EAQ83371.1 - 6.7e-26 91.2 0.2 2.7e-25 89.2 0.1 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Fasciclin PF02469.17 EAQ83373.1 - 5.3e-36 123.4 0.4 5.9e-27 94.2 0.1 2.3 2 0 0 2 2 2 2 Fasciclin domain Pro_CA PF00484.14 EAQ83374.1 - 2.9e-49 167.0 0.1 4.2e-49 166.4 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase NACHT PF05729.7 EAQ83375.1 - 4.8e-13 49.0 0.7 2.3e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EAQ83375.1 - 2.2e-05 24.6 1.1 0.0072 16.5 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ83375.1 - 0.00011 22.2 2.3 0.00058 19.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ83375.1 - 0.00013 22.1 0.3 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EAQ83375.1 - 0.00038 19.5 2.3 0.23 10.4 0.1 3.0 2 1 0 2 2 2 2 KAP family P-loop domain AAA_35 PF14516.1 EAQ83375.1 - 0.044 12.4 0.1 0.069 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EAQ83375.1 - 0.044 13.6 0.1 0.35 10.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAQ83375.1 - 0.066 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EAQ83375.1 - 0.093 13.0 0.3 0.79 10.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EAQ83376.1 - 3.7e-50 168.2 1.6 6.1e-16 58.5 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ83376.1 - 4.2e-42 139.9 6.0 2.1e-07 30.4 0.0 8.3 7 1 1 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EAQ83376.1 - 1.7e-30 102.0 0.6 4.3e-06 26.4 0.0 8.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EAQ83376.1 - 3.3e-29 100.2 6.1 8.8e-07 28.9 0.1 6.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ83376.1 - 4.6e-28 97.0 2.1 3.7e-07 30.4 0.0 6.2 2 1 6 8 8 8 7 Ankyrin repeats (many copies) NMT1 PF09084.6 EAQ83377.1 - 1.4e-76 256.8 0.0 2.2e-76 256.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EAQ83377.1 - 4e-08 32.9 0.8 0.014 14.8 0.1 3.7 2 1 2 4 4 4 2 NMT1-like family AAA PF00004.24 EAQ83379.1 - 3e-37 127.7 0.0 6e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EAQ83379.1 - 3.2e-09 36.5 0.9 1.6e-08 34.3 0.0 2.5 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.1 EAQ83379.1 - 1.2e-05 25.4 0.0 0.00014 21.9 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAQ83379.1 - 3.2e-05 24.7 0.0 9.9e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ83379.1 - 3.2e-05 23.4 0.1 0.091 12.1 0.0 3.2 2 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 EAQ83379.1 - 8.4e-05 21.7 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAQ83379.1 - 0.00011 22.3 0.1 0.0073 16.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAQ83379.1 - 0.0003 20.2 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EAQ83379.1 - 0.00068 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAQ83379.1 - 0.0027 16.8 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 EAQ83379.1 - 0.0084 15.8 0.0 0.078 12.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EAQ83379.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus HET PF06985.6 EAQ83379.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 1 0 Heterokaryon incompatibility protein (HET) AAA_33 PF13671.1 EAQ83379.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAQ83379.1 - 0.021 15.0 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 EAQ83379.1 - 0.031 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EAQ83379.1 - 0.032 14.5 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EAQ83379.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ83379.1 - 0.037 13.7 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EAQ83379.1 - 0.037 13.7 0.0 1.4 8.5 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 EAQ83379.1 - 0.037 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Torsin Mg_chelatase PF01078.16 EAQ83379.1 - 0.086 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EAQ83379.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 EAQ83379.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EAQ83379.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EAQ83379.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 EAQ83379.1 - 0.3 10.5 0.0 0.63 9.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EAQ83379.1 - 0.33 9.8 0.0 0.96 8.3 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_21 PF13304.1 EAQ83379.1 - 0.36 10.7 0.2 2.5 7.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain IFRD PF05004.8 EAQ83381.1 - 0.26 10.3 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) FAD_binding_3 PF01494.14 EAQ83382.1 - 7.9e-18 64.6 0.0 1.4e-17 63.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EAQ83382.1 - 3.9e-06 27.1 0.0 6.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ83382.1 - 0.00032 20.6 0.1 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ83382.1 - 0.00069 18.6 0.0 0.0019 17.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 EAQ83382.1 - 0.00097 18.0 0.0 0.0019 17.0 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.9 EAQ83382.1 - 0.002 16.7 0.0 0.0032 16.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EAQ83382.1 - 0.0027 17.5 0.0 0.0043 16.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ83382.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EAQ83382.1 - 0.0083 15.2 0.5 0.027 13.5 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EAQ83382.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 EAQ83383.1 - 1.8e-45 155.1 0.2 2.1e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EAQ83383.1 - 1.5e-05 24.7 5.8 4.5e-05 23.2 4.0 1.9 1 0 0 1 1 1 1 MYND finger Cornichon PF03311.9 EAQ83384.1 - 1.4e-34 118.9 6.8 2.1e-34 118.4 4.7 1.2 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 EAQ83384.1 - 2.7e-34 115.8 7.0 9.6e-10 37.9 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EAQ83384.1 - 9.9e-05 21.9 0.0 0.00044 19.7 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain ADH_N PF08240.7 EAQ83385.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ83385.1 - 0.084 12.4 0.7 0.18 11.3 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Amidoligase_2 PF12224.3 EAQ83387.1 - 4.4e-08 33.0 0.0 8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Putative amidoligase enzyme DUF1748 PF08520.5 EAQ83388.1 - 1.5e-14 53.3 0.1 1.6e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 EAQ83389.1 - 3.7e-120 400.6 0.7 5.5e-120 400.1 0.5 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EAQ83389.1 - 1.1e-29 102.4 0.0 2.1e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EAQ83389.1 - 0.00018 20.4 0.9 0.00061 18.7 0.4 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Dynamin_N PF00350.18 EAQ83390.1 - 6.1e-20 71.6 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAQ83390.1 - 2.6e-09 36.2 0.0 9.2e-09 34.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region NAD_binding_10 PF13460.1 EAQ83392.1 - 2.2e-20 73.4 0.6 2.5e-18 66.7 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ83392.1 - 0.0029 17.0 0.0 0.014 14.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 EAQ83394.1 - 1.7e-18 66.4 0.0 3.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ83394.1 - 8.6e-05 22.3 8.3 0.00016 21.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EAQ83395.1 - 1.2 8.4 8.5 1.2 8.4 5.9 1.1 1 0 0 1 1 1 0 Vta1 like RNase_T PF00929.19 EAQ83398.1 - 1.8e-09 38.0 0.0 1.6e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 Exonuclease Med2 PF11214.3 EAQ83398.1 - 4.9 7.2 6.4 3.3 7.7 2.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 MFS_1 PF07690.11 EAQ83399.1 - 9.4e-09 34.4 11.5 9.4e-09 34.4 8.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 EAQ83399.1 - 0.032 12.7 11.1 0.36 9.2 7.7 2.0 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like DoxD PF04173.8 EAQ83399.1 - 0.46 10.1 4.7 4.6 6.8 1.7 2.2 1 1 1 2 2 2 0 TQO small subunit DoxD Glyco_hydro_61 PF03443.9 EAQ83401.1 - 2.2e-52 178.0 0.2 2.5e-52 177.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 EAQ83402.1 - 8.1e-45 152.9 0.0 1.7e-44 151.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83402.1 - 6e-32 110.7 0.0 8.5e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ83402.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAQ83402.1 - 0.008 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ83402.1 - 0.016 14.9 2.4 0.1 12.3 0.0 2.9 3 1 1 4 4 4 0 Phosphotransferase enzyme family Spt5-NGN PF03439.8 EAQ83405.1 - 1.7e-24 85.3 0.0 3e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EAQ83405.1 - 9.2e-18 64.6 10.5 9.2e-18 64.6 7.3 4.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EAQ83405.1 - 7.2e-14 52.2 22.5 7.2e-14 52.2 15.6 4.1 3 1 1 4 4 4 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EAQ83405.1 - 0.0054 16.3 0.7 0.0054 16.3 0.5 5.0 5 1 0 5 5 5 2 KOW motif SAPS PF04499.10 EAQ83405.1 - 2 6.9 6.8 3.2 6.3 4.7 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Amidoligase_2 PF12224.3 EAQ83406.1 - 2.7e-09 37.0 0.0 7.8e-09 35.5 0.0 1.7 1 1 1 2 2 2 1 Putative amidoligase enzyme Abhydrolase_6 PF12697.2 EAQ83408.1 - 5.9e-14 52.4 4.5 9.4e-14 51.8 3.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ83408.1 - 5.2e-12 45.7 1.4 7.8e-12 45.1 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ83408.1 - 7.4e-07 28.9 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EAQ83408.1 - 0.00022 20.9 0.8 0.00038 20.0 0.6 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EAQ83408.1 - 0.015 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) NMT_C PF02799.10 EAQ83410.1 - 1.9e-79 265.4 0.0 2.8e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EAQ83410.1 - 4e-66 221.6 0.0 6.2e-66 221.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EAQ83410.1 - 5.2e-06 26.3 0.0 9.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAQ83410.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4604 PF15377.1 EAQ83410.1 - 0.91 9.7 17.4 1.7 8.8 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF2201_N PF13203.1 EAQ83410.1 - 9.1 5.3 8.7 14 4.7 6.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Abhydrolase_6 PF12697.2 EAQ83411.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tannase PF07519.6 EAQ83412.1 - 9.1e-76 255.4 1.1 4e-71 240.1 0.7 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EAQ83412.1 - 0.0024 17.7 0.7 0.0037 17.1 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ83412.1 - 0.025 14.1 0.8 0.06 12.8 0.4 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.20 EAQ83414.1 - 6.9e-16 58.6 0.9 2.9e-15 56.5 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ83414.1 - 9.5e-11 41.9 0.0 1.6e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ83414.1 - 6.7e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ83414.1 - 1.3e-05 24.6 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.10 EAQ83414.1 - 0.00034 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1776 PF08643.5 EAQ83414.1 - 0.0022 17.1 0.0 0.0083 15.3 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.11 EAQ83414.1 - 0.004 16.5 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DFP PF04127.10 EAQ83414.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.13 EAQ83414.1 - 0.044 13.7 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.5 EAQ83414.1 - 0.05 13.2 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 KR domain 3HCDH_N PF02737.13 EAQ83414.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_114 PF03537.8 EAQ83415.1 - 9.4e-10 38.1 0.1 1.9e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF2360 PF10152.4 EAQ83416.1 - 0.069 13.4 0.6 0.11 12.8 0.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Polysacc_synt_4 PF04669.8 EAQ83417.1 - 5.7e-27 94.3 1.9 2.8e-26 92.0 1.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Elongin_A PF06881.6 EAQ83417.1 - 0.0064 16.8 0.6 0.01 16.2 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2491 PF10679.4 EAQ83417.1 - 0.11 11.4 1.1 0.13 11.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Peroxin-22 PF12827.2 EAQ83417.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family ABC_membrane PF00664.18 EAQ83418.1 - 1.7e-33 116.1 7.6 3.7e-11 42.9 0.1 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ83418.1 - 4.9e-26 91.6 0.0 4.2e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.1 EAQ83418.1 - 5.2e-07 30.5 0.2 0.024 15.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAQ83418.1 - 1.7e-06 27.5 0.1 0.13 11.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EAQ83418.1 - 2.2e-06 27.0 3.7 0.007 15.8 1.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAQ83418.1 - 2.7e-06 27.5 0.1 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EAQ83418.1 - 4.8e-06 25.8 0.0 0.034 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 EAQ83418.1 - 5.5e-06 26.5 0.0 0.087 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAQ83418.1 - 1.1e-05 25.5 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EAQ83418.1 - 1.1e-05 25.7 0.2 0.24 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAQ83418.1 - 0.0002 21.2 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ83418.1 - 0.0017 18.0 0.5 1.3 8.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EAQ83418.1 - 0.0019 18.5 1.5 0.56 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EAQ83418.1 - 0.0044 16.6 1.1 4.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_10 PF12846.2 EAQ83418.1 - 0.0064 15.9 1.0 0.67 9.3 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_19 PF13245.1 EAQ83418.1 - 0.0071 16.0 0.6 0.71 9.6 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EAQ83418.1 - 0.0092 15.0 0.4 1.3 8.0 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin SMC_N PF02463.14 EAQ83418.1 - 0.0097 15.1 0.5 7.6 5.6 0.1 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MobB PF03205.9 EAQ83418.1 - 0.011 15.4 0.3 6 6.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EAQ83418.1 - 0.013 15.3 1.0 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Miro PF08477.8 EAQ83418.1 - 0.022 15.2 0.0 23 5.4 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein AAA_14 PF13173.1 EAQ83418.1 - 0.026 14.4 0.0 2 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EAQ83418.1 - 0.034 13.3 0.0 9 5.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAQ83418.1 - 0.036 14.2 0.1 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EAQ83418.1 - 0.04 12.7 0.3 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 EAQ83418.1 - 0.043 13.7 1.8 0.62 10.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EAQ83418.1 - 0.043 13.3 0.4 0.87 9.0 0.1 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EAQ83418.1 - 0.065 12.8 1.0 6.5 6.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EAQ83418.1 - 0.079 12.0 2.3 9.5 5.2 0.1 3.5 4 0 0 4 4 4 0 KaiC PEPCK_ATP PF01293.15 EAQ83418.1 - 0.091 11.2 0.8 0.55 8.7 0.0 2.3 3 0 0 3 3 3 0 Phosphoenolpyruvate carboxykinase AAA_30 PF13604.1 EAQ83418.1 - 0.094 12.2 0.0 20 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EAQ83418.1 - 0.12 11.8 0.1 6.4 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 EAQ83418.1 - 0.12 11.9 0.1 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 EAQ83418.1 - 0.24 10.6 1.0 7.5 5.7 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 EAQ83418.1 - 0.27 11.4 0.9 4.4 7.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF463 PF04317.7 EAQ83419.1 - 0.0029 16.2 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 YcjX-like family, DUF463 MFS_1 PF07690.11 EAQ83420.1 - 1.1e-28 100.0 35.2 3.4e-27 95.0 12.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAQ83420.1 - 1.6e-12 46.4 3.2 2.5e-12 45.7 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tim54 PF11711.3 EAQ83420.1 - 0.25 9.8 1.0 0.37 9.3 0.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF912 PF06024.7 EAQ83420.1 - 0.32 11.0 5.3 0.1 12.6 1.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Methyltransf_29 PF03141.11 EAQ83420.1 - 0.41 8.9 1.1 0.6 8.3 0.7 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1769 PF08588.5 EAQ83421.1 - 2.5e-28 97.7 0.4 4.9e-28 96.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MCLC PF05934.6 EAQ83421.1 - 0.016 13.5 0.3 0.023 13.0 0.2 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) PC_rep PF01851.17 EAQ83422.1 - 3.4e-39 130.8 18.5 8.5e-09 35.1 0.0 9.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EAQ83422.1 - 1.2e-18 67.1 2.7 3.3e-12 46.5 0.0 5.9 3 1 3 7 7 7 3 HEAT repeats HEAT PF02985.17 EAQ83422.1 - 3.6e-09 35.9 0.2 0.81 9.9 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EAQ83422.1 - 1.6e-08 34.7 1.6 5.6e-05 23.5 0.0 5.3 4 1 1 5 5 5 1 HEAT-like repeat Utp13 PF08625.6 EAQ83422.1 - 0.14 11.8 0.1 0.46 10.1 0.0 1.9 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Apc3 PF12895.2 EAQ83422.1 - 0.17 12.0 0.4 4.7 7.4 0.1 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 mRNA_triPase PF02940.10 EAQ83423.1 - 3.7e-55 186.9 0.0 5.7e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain NmrA PF05368.8 EAQ83424.1 - 1e-22 80.5 0.4 3.9e-22 78.6 0.3 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ83424.1 - 8e-16 58.5 2.1 5.3e-15 55.9 0.9 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EAQ83424.1 - 4.7e-07 29.4 0.0 7.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ83424.1 - 0.0028 16.5 0.6 0.0047 15.8 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EAQ83424.1 - 0.0055 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ83424.1 - 0.016 15.6 0.0 0.073 13.5 0.0 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EAQ83424.1 - 0.021 14.6 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KIP1 PF07765.7 EAQ83424.1 - 0.044 13.6 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 KIP1-like protein 3Beta_HSD PF01073.14 EAQ83424.1 - 0.058 12.0 0.0 0.12 11.0 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_8 PF13450.1 EAQ83425.1 - 1.4e-11 44.2 0.5 3.5e-11 42.9 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EAQ83425.1 - 6.2e-09 35.4 0.8 1.2e-08 34.5 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EAQ83425.1 - 2.8e-07 29.9 0.1 2.1e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EAQ83425.1 - 1e-06 27.8 0.9 1.6e-06 27.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EAQ83425.1 - 8.5e-06 24.4 0.3 1.2e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EAQ83425.1 - 1.5e-05 25.2 0.4 3.1e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ83425.1 - 2.7e-05 24.3 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ83425.1 - 6.4e-05 22.0 1.0 6.4e-05 22.0 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ83425.1 - 0.00042 20.2 0.6 0.00071 19.5 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ83425.1 - 0.00043 19.4 0.7 0.00085 18.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EAQ83425.1 - 0.00054 19.1 0.4 0.00087 18.4 0.3 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EAQ83425.1 - 0.0018 17.1 0.5 0.003 16.4 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DUF799 PF05643.6 EAQ83425.1 - 0.026 13.8 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative bacterial lipoprotein (DUF799) IlvN PF07991.7 EAQ83425.1 - 0.23 10.8 1.5 0.33 10.3 0.2 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_4 PF01565.18 EAQ83426.1 - 1.8e-19 69.6 0.2 5.1e-19 68.1 0.2 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ83426.1 - 0.024 14.5 0.1 0.071 13.0 0.1 1.8 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.17 EAQ83428.1 - 1.9e-34 118.9 0.0 5.4e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EAQ83429.1 - 6.1e-40 137.0 59.2 6.1e-40 137.0 41.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ83429.1 - 1.5e-12 46.5 16.5 2.5e-12 45.8 11.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EAQ83429.1 - 1.5e-08 33.6 14.8 1.5e-08 33.6 10.3 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 EAQ83430.1 - 3.8e-10 38.8 0.2 9.6e-10 37.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Dimer_Tnp_hAT PF05699.9 EAQ83431.1 - 8.1e-13 47.8 0.1 1.9e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HRXXH PF13933.1 EAQ83432.1 - 1.4e-103 345.6 0.0 1.7e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.10 EAQ83432.1 - 0.00011 20.9 1.3 0.0003 19.5 0.0 2.2 2 1 0 2 2 2 1 Deuterolysin metalloprotease (M35) family Mannosyl_trans3 PF11051.3 EAQ83433.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EAQ83433.1 - 0.0014 18.0 0.2 0.003 16.9 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_hydro_62 PF03664.8 EAQ83435.1 - 1.2e-141 470.6 7.1 1.3e-141 470.4 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 zf-C2H2 PF00096.21 EAQ83437.1 - 2.4e-06 27.5 3.4 0.011 16.0 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ83437.1 - 0.00019 21.5 3.4 0.021 15.1 0.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ83437.1 - 0.0062 16.6 2.1 2.8 8.1 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EAQ83437.1 - 0.057 13.5 1.2 3.8 7.7 0.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 EAQ83437.1 - 0.069 13.2 0.6 0.16 12.0 0.4 1.6 1 1 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.1 EAQ83437.1 - 0.1 12.5 3.1 3.8 7.5 0.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger DUF4360 PF14273.1 EAQ83439.1 - 3.9e-13 49.4 0.1 4.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Kinesin PF00225.18 EAQ83440.1 - 2.3e-113 378.2 0.0 3.6e-113 377.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EAQ83440.1 - 0.0096 15.7 2.1 0.021 14.5 1.5 1.6 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA PF00004.24 EAQ83440.1 - 0.14 12.3 0.4 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.19 EAQ83441.1 - 1.3e-112 376.7 25.5 2e-112 376.0 17.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83441.1 - 1.8e-26 92.7 58.4 3.4e-22 78.6 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ83441.1 - 0.0042 15.5 34.2 0.06 11.7 7.4 3.2 2 2 0 3 3 3 2 MFS/sugar transport protein Lysis_S PF04971.7 EAQ83441.1 - 0.057 13.1 0.2 0.27 10.9 0.2 2.2 1 0 0 1 1 1 0 Lysis protein S Myb_DNA-bind_6 PF13921.1 EAQ83443.1 - 1.1e-06 28.6 1.6 1e-05 25.5 0.2 2.4 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ83443.1 - 0.0014 18.6 0.2 0.0035 17.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain UbiA PF01040.13 EAQ83444.1 - 3.2e-32 111.7 22.4 3.2e-32 111.7 15.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family PBP1_TM PF14812.1 EAQ83444.1 - 0.16 12.3 2.0 0.38 11.0 1.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EAQ83444.1 - 0.16 11.4 2.5 0.26 10.8 1.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EAQ83444.1 - 3.2 8.0 9.5 5.8 7.2 6.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RdRP_3 PF00998.18 EAQ83446.1 - 0.14 10.6 0.7 0.23 9.9 0.5 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Mo-co_dimer PF03404.11 EAQ83447.1 - 3.5e-28 97.8 0.0 9.5e-18 64.0 0.0 3.2 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EAQ83447.1 - 8.8e-13 47.8 0.0 1.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.15 EAQ83447.1 - 0.36 10.8 4.3 0.72 9.9 0.1 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF3506 PF12014.3 EAQ83448.1 - 6.1e-41 139.4 0.0 1.6e-40 138.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) Nucleoplasmin PF03066.10 EAQ83448.1 - 0.17 11.3 2.9 0.21 11.0 2.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EAQ83448.1 - 1.7 8.2 5.5 2.5 7.6 3.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cupin_2 PF07883.6 EAQ83450.1 - 1e-07 31.3 0.6 1.9e-07 30.4 0.4 1.6 1 1 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EAQ83450.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 EAQ83450.1 - 0.043 13.5 0.1 0.059 13.0 0.1 1.3 1 1 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.2 EAQ83450.1 - 0.09 12.3 0.1 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Cupin MscS_porin PF12795.2 EAQ83451.1 - 0.0023 17.3 3.0 0.0023 17.3 2.1 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain Arteri_nucleo PF01481.11 EAQ83451.1 - 0.034 14.2 1.4 0.073 13.1 1.0 1.5 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein DUF972 PF06156.8 EAQ83451.1 - 3.9 7.8 5.2 4.8 7.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) F-box-like_2 PF13013.1 EAQ83452.1 - 0.027 14.1 0.1 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain Phage_GP20 PF06810.6 EAQ83453.1 - 0.0031 16.9 1.3 0.0031 16.9 0.9 3.0 3 0 0 3 3 3 1 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 EAQ83453.1 - 0.027 14.5 1.7 0.027 14.5 1.2 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc42p PF11544.3 EAQ83453.1 - 0.046 13.6 2.5 13 5.8 0.3 3.3 3 0 0 3 3 3 0 Spindle pole body component Spc42p DUF641 PF04859.7 EAQ83453.1 - 0.1 12.3 13.8 0.42 10.3 1.2 4.0 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 EAQ83453.1 - 0.11 11.6 10.7 0.054 12.6 0.2 3.2 3 1 0 3 3 3 0 Reovirus sigma C capsid protein Bap31 PF05529.7 EAQ83453.1 - 0.59 9.5 7.1 0.51 9.7 0.7 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4094 PF13334.1 EAQ83453.1 - 1.1 9.6 5.7 2.4 8.5 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) GAS PF13851.1 EAQ83453.1 - 1.8 7.7 18.9 0.33 10.1 2.5 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EAQ83453.1 - 3.3 6.2 15.7 0.058 12.0 2.1 2.7 3 0 0 3 3 3 0 Spc7 kinetochore protein APG6 PF04111.7 EAQ83453.1 - 3.6 6.5 18.7 0.44 9.5 1.5 2.9 3 0 0 3 3 3 0 Autophagy protein Apg6 TBPIP PF07106.8 EAQ83453.1 - 8.7 5.8 12.8 3.8 7.0 2.0 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DEAD PF00270.24 EAQ83457.1 - 8.5e-42 142.5 0.0 1.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ83457.1 - 1.2e-23 82.7 0.1 2.1e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ83457.1 - 0.017 14.9 0.1 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecE PF00584.15 EAQ83459.1 - 0.16 11.5 0.1 0.38 10.3 0.0 1.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Gly_transf_sug PF04488.10 EAQ83461.1 - 3.5e-06 27.3 0.0 4.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EAQ83461.1 - 0.0033 16.6 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein HemX PF04375.9 EAQ83462.1 - 0.024 13.2 1.5 0.032 12.8 1.1 1.1 1 0 0 1 1 1 0 HemX DAP10 PF07213.6 EAQ83462.1 - 0.061 13.0 0.8 0.15 11.8 0.6 1.6 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.1 EAQ83462.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family GRP PF07172.6 EAQ83462.1 - 7.7 7.0 19.4 16 6.0 13.5 1.5 1 1 0 1 1 1 0 Glycine rich protein family Fungal_trans PF04082.13 EAQ83463.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1479 PF07350.7 EAQ83464.1 - 7.5e-157 522.0 0.0 8.6e-157 521.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EAQ83464.1 - 0.0049 16.9 0.1 0.83 9.6 0.0 2.5 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1993 PF09351.5 EAQ83465.1 - 3.5e-50 170.0 0.0 4e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) p450 PF00067.17 EAQ83472.1 - 1.6e-28 99.4 0.0 7e-24 84.1 0.0 3.0 1 1 0 1 1 1 1 Cytochrome P450 PYRIN PF02758.11 EAQ83472.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain DUF1996 PF09362.5 EAQ83473.1 - 4.4e-62 209.8 0.6 4.1e-30 105.1 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) zf-C2H2_4 PF13894.1 EAQ83474.1 - 0.00041 20.4 21.5 1.2 9.6 0.6 5.5 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ83474.1 - 0.19 11.9 9.0 0.047 13.8 0.7 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DZR PF12773.2 EAQ83474.1 - 0.63 9.8 3.6 3.5 7.5 0.3 3.0 3 0 0 3 3 3 0 Double zinc ribbon zf-C2H2 PF00096.21 EAQ83474.1 - 0.71 10.3 18.8 5.2 7.6 0.3 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type Nop PF01798.13 EAQ83475.1 - 1.7e-54 183.2 0.1 2.8e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EAQ83475.1 - 1e-22 79.6 0.0 2.3e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EAQ83475.1 - 6.4e-19 67.8 0.0 6.4e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EAQ83475.1 - 0.028 14.1 20.5 0.046 13.3 14.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3525 PF12039.3 EAQ83475.1 - 0.035 12.6 0.2 0.21 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) DUF3086 PF11285.3 EAQ83475.1 - 0.039 12.7 0.6 0.33 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) AAA PF00004.24 EAQ83476.1 - 1.2e-42 145.2 0.0 2.3e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EAQ83476.1 - 3.6e-29 100.4 0.1 3.3e-28 97.3 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EAQ83476.1 - 1.8e-22 78.9 2.6 5.7e-22 77.3 1.5 2.2 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EAQ83476.1 - 2.1e-06 28.5 0.2 3e-05 24.8 0.0 2.9 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 EAQ83476.1 - 7.6e-06 25.1 0.0 1.5e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EAQ83476.1 - 1.5e-05 24.4 0.7 0.15 11.4 0.1 3.4 1 1 2 3 3 3 2 AAA domain AAA_22 PF13401.1 EAQ83476.1 - 1.7e-05 24.9 0.1 0.0016 18.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAQ83476.1 - 2.5e-05 23.7 0.0 5.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EAQ83476.1 - 2.9e-05 23.7 0.0 0.00019 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ83476.1 - 3.4e-05 23.9 0.2 0.00066 19.7 0.0 2.8 3 1 1 4 4 2 1 AAA ATPase domain AAA_14 PF13173.1 EAQ83476.1 - 4e-05 23.5 0.0 9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAQ83476.1 - 5.4e-05 23.3 0.0 0.011 15.8 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EAQ83476.1 - 0.00014 21.7 0.0 0.00058 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EAQ83476.1 - 0.00018 20.3 0.0 0.00037 19.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EAQ83476.1 - 0.00031 19.7 0.0 0.00079 18.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EAQ83476.1 - 0.0011 18.9 0.0 0.0042 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EAQ83476.1 - 0.0051 16.4 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EAQ83476.1 - 0.0064 16.1 0.0 0.35 10.4 0.0 2.6 2 1 1 3 3 3 1 NACHT domain AAA_18 PF13238.1 EAQ83476.1 - 0.01 16.1 0.0 0.036 14.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EAQ83476.1 - 0.013 14.5 0.1 0.17 10.9 0.0 2.6 2 1 1 3 3 3 0 Zeta toxin AAA_19 PF13245.1 EAQ83476.1 - 0.015 15.0 0.0 0.063 13.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EAQ83476.1 - 0.021 14.5 0.0 0.21 11.2 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 EAQ83476.1 - 0.023 13.8 0.0 0.065 12.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EAQ83476.1 - 0.026 14.4 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Torsin Peptidase_M28 PF04389.12 EAQ83476.1 - 0.033 13.9 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M28 ResIII PF04851.10 EAQ83476.1 - 0.042 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EAQ83476.1 - 0.045 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EAQ83476.1 - 0.094 11.9 0.0 0.094 11.9 0.0 1.8 2 0 0 2 2 1 0 PhoH-like protein CPT PF07931.7 EAQ83476.1 - 0.11 12.1 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EAQ83476.1 - 0.11 11.9 0.0 0.38 10.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 EAQ83476.1 - 0.13 11.6 0.0 0.4 10.0 0.0 1.9 1 0 0 1 1 1 0 Guanylate kinase ABC_tran PF00005.22 EAQ83476.1 - 0.15 12.3 0.2 1.6 9.0 0.0 2.6 3 1 0 3 3 2 0 ABC transporter Bac_DnaA PF00308.13 EAQ83476.1 - 0.15 11.6 0.0 0.97 9.0 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_21 PF13304.1 EAQ83476.1 - 0.16 11.8 0.3 3.6 7.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 EAQ83477.1 - 1.6e-17 63.2 7.5 2.4e-17 62.6 5.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Lzipper-MIP1 PF14389.1 EAQ83477.1 - 0.028 14.5 2.7 0.058 13.5 1.8 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4601 PF15373.1 EAQ83477.1 - 0.077 11.8 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) MotA_ExbB PF01618.11 EAQ83477.1 - 0.12 12.0 1.6 9.7 5.8 0.0 2.5 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family NPV_P10 PF05531.7 EAQ83477.1 - 0.12 12.6 1.7 0.23 11.7 1.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EAQ83477.1 - 1.7 7.7 8.9 2 7.5 3.7 2.4 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EAQ83477.1 - 4.5 6.8 10.6 5 6.6 4.6 2.5 2 1 0 2 2 2 0 Septum formation initiator JAB PF01398.16 EAQ83478.1 - 1.5e-15 56.9 0.0 2.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EAQ83478.1 - 5.8e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EAQ83478.1 - 1.7e-05 24.3 0.0 4.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Beta-lactamase PF00144.19 EAQ83479.1 - 2.2e-16 59.8 1.6 4.5e-08 32.4 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase HET PF06985.6 EAQ83480.1 - 1.1e-13 51.4 4.7 1.2e-13 51.4 0.7 2.8 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) ApoO PF09769.4 EAQ83480.1 - 0.085 12.5 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein O PRCC PF10253.4 EAQ83480.1 - 6.7 7.3 8.6 1.1 9.9 0.3 3.1 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting GMC_oxred_N PF00732.14 EAQ83481.1 - 1.6e-44 152.2 1.9 2.5e-44 151.6 1.3 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ83481.1 - 7.2e-29 100.9 0.1 5.3e-28 98.1 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EAQ83481.1 - 9.8e-06 24.7 2.7 6.1e-05 22.0 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ83481.1 - 0.022 14.7 0.1 0.061 13.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ83481.1 - 0.09 12.6 0.3 10 5.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 EAQ83482.1 - 1.7e-24 85.8 1.4 3.2e-24 84.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ83482.1 - 9.2e-11 41.4 0.0 2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_3 PF07859.8 EAQ83482.1 - 0.00016 21.3 7.6 0.24 10.9 0.0 3.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold adh_short PF00106.20 EAQ83483.1 - 3.4e-28 98.6 0.0 5.6e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ83483.1 - 2.9e-10 40.1 0.0 5.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EAQ83483.1 - 2.7e-06 26.2 0.0 3.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ83483.1 - 7.7e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ83483.1 - 0.019 14.9 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 EAQ83483.1 - 0.022 13.6 0.1 0.059 12.2 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EAQ83483.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PALP PF00291.20 EAQ83483.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Pyr_redox_3 PF13738.1 EAQ83484.1 - 1.1e-14 54.9 0.0 2.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ83484.1 - 1e-05 23.9 0.0 1.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EAQ83484.1 - 0.001 18.0 0.0 0.0034 16.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EAQ83484.1 - 0.021 13.6 0.1 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Zn_peptidase_2 PF04298.7 EAQ83484.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase PIF1 PF05970.9 EAQ83485.1 - 6.2e-07 28.6 0.1 1.1e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ83485.1 - 0.00012 22.1 0.0 0.00042 20.4 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ83485.1 - 0.026 14.6 0.1 0.067 13.3 0.1 1.7 1 0 0 1 1 1 0 Helicase associated domain DUF605 PF04652.11 EAQ83486.1 - 3.8 6.7 25.9 5.5 6.2 18.0 1.1 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 EAQ83487.1 - 5.3e-28 97.6 0.0 7.9e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 EAQ83488.1 - 6.8e-32 109.6 16.1 1.5e-15 57.3 1.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ83488.1 - 4.5e-21 74.8 14.3 1.8e-09 37.8 0.3 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EAQ83488.1 - 4e-20 70.5 13.3 5.1e-07 29.1 0.3 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EAQ83488.1 - 9.5e-16 57.4 13.5 3.8e-05 23.7 0.5 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ83488.1 - 1.1e-14 53.0 11.1 0.0003 20.7 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat CD99L2 PF12301.3 EAQ83489.1 - 0.11 12.1 11.3 0.16 11.6 7.8 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 PIF1 PF05970.9 EAQ83491.1 - 4e-31 108.2 0.0 1.6e-24 86.5 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ83491.1 - 1.9e-05 24.3 0.0 0.00027 20.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EAQ83491.1 - 4.4e-05 21.4 0.0 0.00021 19.2 0.0 1.8 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EAQ83491.1 - 0.0006 19.9 0.0 0.003 17.6 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ83491.1 - 0.0026 17.4 0.1 0.0059 16.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 EAQ83491.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Torsin CorA PF01544.13 EAQ83492.1 - 1e-07 31.3 0.1 1e-07 31.3 0.1 2.6 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein PTRF_SDPR PF15237.1 EAQ83492.1 - 0.021 14.2 0.1 0.021 14.2 0.1 2.0 2 0 0 2 2 2 0 PTRF/SDPR family DUF948 PF06103.6 EAQ83492.1 - 0.06 13.2 2.5 0.073 12.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.7 EAQ83492.1 - 0.3 9.8 11.0 0.017 13.9 3.0 2.1 3 0 0 3 3 3 0 Autophagy protein Apg17 DEAD PF00270.24 EAQ83493.1 - 1.8e-20 73.0 0.0 3.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ83493.1 - 1.4e-11 44.5 0.0 1.5e-10 41.1 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAQ83493.1 - 3.2e-08 33.3 0.2 6.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EAQ83493.1 - 0.0055 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Inositol_P PF00459.20 EAQ83495.1 - 4.2e-23 82.0 1.6 8.3e-23 81.0 0.0 2.2 2 1 0 2 2 2 1 Inositol monophosphatase family TFIIA PF03153.8 EAQ83495.1 - 0.34 10.7 23.7 0.48 10.2 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LysM PF01476.15 EAQ83496.1 - 4.4e-20 71.3 6.7 8e-08 32.0 0.0 6.3 6 0 0 6 6 6 5 LysM domain Glyco_hydro_18 PF00704.23 EAQ83497.1 - 3.4e-65 220.7 0.0 5e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EAQ83497.1 - 9.7e-08 31.8 21.2 6.5e-07 29.2 5.3 2.6 2 0 0 2 2 2 2 Chitin recognition protein Reprolysin_5 PF13688.1 EAQ83498.1 - 0.003 17.5 0.2 0.0069 16.3 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAQ83498.1 - 0.0035 17.4 0.1 0.0067 16.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 EAQ83498.1 - 0.017 14.5 0.1 0.079 12.3 0.1 1.9 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 EAQ83498.1 - 0.021 14.3 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAQ83498.1 - 0.13 11.9 2.0 0.43 10.3 1.9 1.7 2 1 0 2 2 2 0 Matrixin Lipase_GDSL_2 PF13472.1 EAQ83499.1 - 1.4e-09 38.3 0.3 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ83499.1 - 8.9e-08 32.2 0.8 7.4e-07 29.2 0.6 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 EAQ83500.1 - 5.5e-24 84.5 49.7 1.2e-21 76.8 34.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ83500.1 - 6.3e-07 27.9 24.9 6.3e-07 27.9 17.3 1.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1962 PF09227.5 EAQ83501.1 - 2.2e-38 130.1 21.3 2.6e-38 129.8 14.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) COesterase PF00135.23 EAQ83502.1 - 1.7e-52 178.8 3.5 1.7e-40 139.2 0.0 2.3 2 1 1 3 3 3 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ83502.1 - 8.1e-08 32.0 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kelch_4 PF13418.1 EAQ83503.1 - 0.0009 18.9 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EAQ83503.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.4 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.1 EAQ83503.1 - 0.0026 17.8 0.5 0.05 13.7 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 EAQ83503.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 EAQ83503.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.1 EAQ83503.1 - 0.044 13.7 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Kelch motif EpsG PF14897.1 EAQ83504.1 - 0.33 9.8 12.6 0.47 9.3 8.8 1.2 1 0 0 1 1 1 0 EpsG family NfeD PF01957.13 EAQ83504.1 - 0.58 10.2 7.1 0.63 10.1 0.3 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4064 PF13273.1 EAQ83504.1 - 1.1 9.3 13.5 0.097 12.7 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Tmemb_185A PF10269.4 EAQ83504.1 - 6.4 6.3 14.2 0.27 10.7 2.9 2.2 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein CBM_17_28 PF03424.9 EAQ83505.1 - 0.15 11.7 0.3 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 17/28) His_Phos_1 PF00300.17 EAQ83507.1 - 6.1e-05 23.1 0.0 0.0051 16.9 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RPE65 PF03055.10 EAQ83508.1 - 1.6e-42 145.7 0.0 2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein bZIP_2 PF07716.10 EAQ83509.1 - 0.31 10.8 8.6 0.97 9.3 6.0 1.8 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_C PF12498.3 EAQ83509.1 - 4.7 8.4 8.0 1.9 9.7 1.8 2.7 1 1 2 3 3 3 0 Basic leucine-zipper C terminal Pro-kuma_activ PF09286.6 EAQ83511.1 - 2.1e-10 40.8 0.0 3.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain OPT PF03169.10 EAQ83512.1 - 1.9e-53 181.8 32.9 2.6e-53 181.4 22.8 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_A24 PF01478.13 EAQ83512.1 - 0.024 14.7 1.2 0.024 14.7 0.9 3.0 3 0 0 3 3 3 0 Type IV leader peptidase family DUF3328 PF11807.3 EAQ83513.1 - 6.6e-53 179.6 0.1 8.3e-53 179.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S8 PF00082.17 EAQ83514.1 - 7.7e-09 35.1 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 EAQ83514.1 - 8.5e-09 35.5 0.1 6.3e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 Pro-kumamolisin, activation domain DUF3328 PF11807.3 EAQ83515.1 - 1.1e-21 77.5 8.1 8.9e-20 71.3 2.9 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF3328) DUF1423 PF07227.6 EAQ83516.1 - 3.6 6.1 10.1 3 6.4 1.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1423) MFS_1 PF07690.11 EAQ83517.1 - 1.2e-52 178.7 33.3 1.2e-52 178.7 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ83517.1 - 4.6e-13 48.5 23.1 1e-11 44.0 16.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ83517.1 - 8.2e-06 24.2 3.9 1.3e-05 23.6 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EAQ83517.1 - 0.038 12.0 2.8 1.5 6.7 1.9 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.19 EAQ83518.1 - 9.1e-34 116.9 0.0 1.2e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ83518.1 - 3.1e-10 39.5 0.2 1.5e-09 37.1 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAQ83518.1 - 5.1e-08 33.2 0.0 0.0031 17.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ83518.1 - 1.7e-07 30.1 0.5 2.3e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EAQ83518.1 - 2.9e-06 27.3 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ83518.1 - 3.7e-06 26.1 0.3 1.5e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EAQ83518.1 - 1.4e-05 25.0 0.5 3.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EAQ83518.1 - 3.9e-05 22.9 0.0 0.00021 20.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EAQ83518.1 - 0.00017 20.6 0.2 0.0021 16.9 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EAQ83518.1 - 0.0014 18.9 0.1 0.0029 17.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ83518.1 - 0.0035 16.3 0.1 0.63 8.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EAQ83518.1 - 0.011 16.0 0.1 0.033 14.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EAQ83518.1 - 0.013 14.4 0.1 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GDI PF00996.13 EAQ83518.1 - 0.042 12.1 0.0 0.066 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EAQ83518.1 - 0.045 12.8 0.2 0.11 11.5 0.1 1.8 1 1 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 EAQ83519.1 - 4.4e-32 111.7 0.2 1.3e-31 110.1 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ83519.1 - 6.9e-09 35.6 0.0 2.2e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ83519.1 - 0.0005 20.1 0.0 0.0035 17.4 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ABC_tran PF00005.22 EAQ83520.1 - 7.8e-51 171.9 0.0 2.3e-28 99.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAQ83520.1 - 7e-37 127.3 29.9 4.9e-23 81.9 9.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EAQ83520.1 - 3.4e-08 33.0 1.5 0.011 15.0 0.1 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EAQ83520.1 - 1.1e-05 24.6 0.0 0.041 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EAQ83520.1 - 2.4e-05 23.7 0.4 0.032 13.7 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ83520.1 - 2.9e-05 24.5 0.2 0.0043 17.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EAQ83520.1 - 5e-05 23.4 0.9 0.032 14.2 0.3 3.7 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.12 EAQ83520.1 - 0.0001 22.1 0.7 0.045 13.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EAQ83520.1 - 0.00012 21.6 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EAQ83520.1 - 0.00012 22.0 0.2 0.51 10.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EAQ83520.1 - 0.00015 22.2 0.1 0.2 12.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EAQ83520.1 - 0.00037 20.3 0.5 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 EAQ83520.1 - 0.001 18.0 0.0 0.014 14.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EAQ83520.1 - 0.004 16.5 2.1 1.6 8.1 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAQ83520.1 - 0.0042 17.9 0.1 2.4 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ83520.1 - 0.015 15.4 0.6 6.7 6.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAQ83520.1 - 0.018 14.1 0.5 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EAQ83520.1 - 0.035 13.8 0.1 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.10 EAQ83520.1 - 0.044 12.4 0.0 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.1 EAQ83520.1 - 0.072 13.4 0.1 16 5.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAQ83520.1 - 0.074 12.9 0.3 11 5.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAQ83520.1 - 0.1 12.0 1.3 12 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EAQ83520.1 - 0.41 10.6 6.0 4.4 7.2 0.2 3.0 2 1 0 2 2 2 0 AAA ATPase domain Med13_N PF11597.3 EAQ83521.1 - 0.11 11.1 0.2 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Tyrosinase PF00264.15 EAQ83522.1 - 2.3e-32 112.9 0.0 3.5e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Chorion_3 PF05387.6 EAQ83525.1 - 0.26 10.7 8.0 0.36 10.2 5.6 1.1 1 0 0 1 1 1 0 Chorion family 3 adh_short PF00106.20 EAQ83526.1 - 2.1e-28 99.3 2.6 2.8e-28 98.9 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ83526.1 - 1.7e-24 86.9 0.1 2.1e-24 86.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ83526.1 - 1.3e-13 51.0 1.1 1.8e-13 50.5 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ83526.1 - 5.4e-05 22.7 0.6 0.0018 17.7 0.4 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EAQ83526.1 - 0.011 15.5 0.6 0.032 14.0 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 EAQ83526.1 - 0.064 12.3 0.1 0.18 10.9 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain N6_Mtase PF02384.11 EAQ83526.1 - 0.082 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_18 PF12847.2 EAQ83526.1 - 0.31 11.6 1.4 1.1 9.9 1.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 EAQ83527.1 - 5.1e-11 41.9 0.0 8.3e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EAQ83528.1 - 5.5e-13 48.6 0.0 7.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ83528.1 - 1.5e-12 47.9 0.1 2.2e-12 47.3 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ83528.1 - 8e-08 31.9 0.0 4.9e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ83528.1 - 0.00052 18.8 0.0 0.00064 18.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EAQ83528.1 - 0.00084 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EAQ83528.1 - 0.0017 18.2 0.1 0.0027 17.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ83528.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EAQ83528.1 - 0.0092 14.9 0.2 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EAQ83528.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EAQ83528.1 - 0.024 13.5 0.2 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 EAQ83528.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain zf-H2C2_2 PF13465.1 EAQ83529.1 - 2.6e-06 27.4 6.1 0.0002 21.4 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ83529.1 - 2.8e-06 27.3 12.6 0.00018 21.6 3.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Orthopox_A36R PF05950.6 EAQ83529.1 - 0.13 12.2 0.3 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein zf-C2H2_4 PF13894.1 EAQ83529.1 - 1 9.8 11.1 4.9 7.7 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Bunya_G2 PF03563.8 EAQ83529.1 - 1.3 7.8 2.8 2.1 7.1 1.9 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 EAQ83529.1 - 1.3 8.9 6.6 0.77 9.7 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger ECH PF00378.15 EAQ83530.1 - 4.3e-37 127.5 0.1 6.1e-35 120.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family WSC PF01822.14 EAQ83530.1 - 5.7e-12 45.4 7.7 7.4e-12 45.0 3.8 2.2 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EAQ83530.1 - 3.3e-07 29.5 1.2 9.6e-07 28.0 0.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 EAQ83530.1 - 0.0044 16.4 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF2076 PF09849.4 EAQ83530.1 - 0.04 13.9 0.2 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CsbD PF05532.7 EAQ83531.1 - 0.0048 16.5 16.2 0.059 13.0 10.5 2.9 1 1 1 2 2 2 2 CsbD-like ISG65-75 PF11727.3 EAQ83531.1 - 0.15 11.1 4.9 0.18 10.8 3.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Dicty_REP PF05086.7 EAQ83531.1 - 0.36 8.5 5.2 0.36 8.5 3.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF883 PF05957.8 EAQ83531.1 - 0.85 10.0 7.6 2 8.8 2.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mucin PF01456.12 EAQ83531.1 - 0.99 9.1 21.4 1.8 8.3 14.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein YtxH PF12732.2 EAQ83531.1 - 2.6 8.4 12.0 0.57 10.5 1.0 2.6 1 1 1 2 2 2 0 YtxH-like protein Dehydratase_hem PF13816.1 EAQ83532.1 - 8.3e-100 333.8 0.0 1.3e-99 333.1 0.0 1.3 1 0 0 1 1 1 1 Haem-containing dehydratase APH PF01636.18 EAQ83532.1 - 6.9e-12 45.6 0.2 7.9e-11 42.1 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4188 PF13826.1 EAQ83532.1 - 6.5e-05 23.0 0.1 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Choline_kinase PF01633.15 EAQ83532.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EAQ83532.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.20 EAQ83532.1 - 0.21 10.7 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain CN_hydrolase PF00795.17 EAQ83533.1 - 1.1e-30 106.4 0.0 1.5e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NicO PF03824.11 EAQ83535.1 - 0.015 14.6 0.7 0.019 14.2 0.5 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 EAQ83535.1 - 0.018 14.0 0.1 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VSP PF03302.8 EAQ83535.1 - 0.064 11.8 0.1 0.083 11.5 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein HAMP PF00672.20 EAQ83535.1 - 0.31 11.2 2.7 0.5 10.5 1.9 1.3 1 0 0 1 1 1 0 HAMP domain Macoilin PF09726.4 EAQ83536.1 - 5.9 5.0 9.8 6.6 4.8 6.8 1.0 1 0 0 1 1 1 0 Transmembrane protein RPW8 PF05659.6 EAQ83537.1 - 0.016 14.7 0.7 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MpPF1 PF07668.6 EAQ83537.1 - 0.016 14.3 0.2 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 LOH1CR12 PF10158.4 EAQ83537.1 - 0.28 10.9 3.1 1.4 8.6 0.5 2.8 3 0 0 3 3 3 0 Tumour suppressor protein VID27 PF08553.5 EAQ83539.1 - 0 1136.9 0.1 0 1136.7 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 EAQ83539.1 - 0.31 8.8 12.8 0.51 8.2 8.9 1.2 1 0 0 1 1 1 0 Nop14-like family Prenylcys_lyase PF07156.9 EAQ83540.1 - 1.9e-31 109.2 0.0 3.2e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EAQ83540.1 - 6.2e-13 48.5 0.1 2.3e-12 46.7 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EAQ83540.1 - 2.6e-09 36.7 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EAQ83540.1 - 1.3e-07 30.8 0.4 0.00022 20.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ83540.1 - 0.0002 21.3 0.6 0.0078 16.1 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ83540.1 - 0.00091 19.0 0.1 0.0023 17.7 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAQ83540.1 - 0.00099 19.2 0.2 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EAQ83540.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Thi4 PF01946.12 EAQ83540.1 - 0.006 15.7 0.3 0.73 8.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EAQ83540.1 - 0.022 13.7 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EAQ83540.1 - 0.038 13.0 0.6 6.5 5.7 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ83540.1 - 0.069 11.9 1.8 0.12 11.2 1.3 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EAQ83540.1 - 0.08 11.5 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EAQ83540.1 - 0.11 11.9 0.2 0.26 10.8 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EAQ83540.1 - 0.17 12.3 0.4 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.19 EAQ83541.1 - 6.6e-119 397.6 2.0 1.6e-95 320.5 0.0 2.1 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 EAQ83542.1 - 2.7e-56 189.6 0.0 4.9e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Totivirus_coat PF05518.6 EAQ83542.1 - 8.6 4.0 6.3 14 3.2 4.4 1.3 1 0 0 1 1 1 0 Totivirus coat protein PCI_Csn8 PF10075.4 EAQ83543.1 - 3e-26 91.9 0.0 5.4e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EAQ83543.1 - 1e-19 70.8 0.0 1.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DNA_ligase_A_M PF01068.16 EAQ83544.1 - 2.7e-48 164.0 0.0 9e-46 155.7 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAQ83544.1 - 1.8e-26 93.0 0.0 3.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EAQ83544.1 - 6.8e-05 23.1 0.0 0.00082 19.7 0.0 2.8 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.15 EAQ83545.1 - 1.4e-58 198.4 0.0 1.6e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase AIP3 PF03915.8 EAQ83546.1 - 0.086 11.7 3.3 0.1 11.4 2.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 TSC22 PF01166.13 EAQ83546.1 - 0.17 11.8 0.8 0.39 10.7 0.2 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family NARP1 PF12569.3 EAQ83546.1 - 0.84 8.3 5.3 1.2 7.7 3.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PCP_red PF08369.5 EAQ83546.1 - 1.5 8.7 5.3 3.8 7.4 3.7 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Aft1_HRR PF11787.3 EAQ83546.1 - 1.9 9.5 6.6 3 8.9 4.6 1.3 1 0 0 1 1 1 0 Aft1 HRR domain MULE PF10551.4 EAQ83547.1 - 2e-09 37.4 0.0 5.4e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.10 EAQ83547.1 - 0.0011 19.4 0.1 0.0035 17.8 0.0 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain Ribosomal_L37 PF08561.5 EAQ83547.1 - 0.047 13.2 0.1 6.6 6.3 0.3 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L37 DUF1917 PF08939.5 EAQ83548.1 - 0.0044 16.7 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF2508 PF10704.4 EAQ83548.1 - 0.14 12.3 0.4 0.26 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) AAL_decarboxy PF03306.8 EAQ83549.1 - 1.1e-75 253.5 0.6 1.2e-75 253.3 0.5 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase HET PF06985.6 EAQ83550.1 - 5.3e-31 107.6 0.8 9e-31 106.8 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UvrD_C_2 PF13538.1 EAQ83552.1 - 0.00046 20.2 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ83552.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Helicase associated domain p450 PF00067.17 EAQ83553.1 - 2.2e-48 164.9 0.0 3.8e-48 164.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 TRP PF06011.7 EAQ83554.1 - 3.9e-31 108.0 18.2 2.3e-17 62.7 2.0 2.7 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel DUF1628 PF07790.6 EAQ83554.1 - 0.038 14.7 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF3328 PF11807.3 EAQ83556.1 - 7.4e-39 133.6 5.3 9e-39 133.3 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.2 EAQ83558.1 - 0.027 14.2 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 F-box-like DUF3350 PF11830.3 EAQ83558.1 - 0.056 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) DUF3767 PF12597.3 EAQ83560.1 - 2.4e-39 133.6 0.0 4.1e-39 132.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) U79_P34 PF03064.11 EAQ83560.1 - 2.5 7.5 7.2 3.2 7.2 5.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4337 PF14235.1 EAQ83560.1 - 5 6.9 5.9 8.3 6.2 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1744 PF08490.7 EAQ83561.1 - 8.1e-133 442.8 0.2 1.2e-124 415.8 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EAQ83561.1 - 4.3e-62 209.8 0.2 7.4e-62 209.0 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EAQ83561.1 - 1.4e-19 70.2 0.1 4.1e-19 68.7 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EAQ83561.1 - 3.1e-09 36.6 0.1 8e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EAQ83561.1 - 1.2e-05 25.1 0.0 3.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily MFS_1 PF07690.11 EAQ83563.1 - 2.1e-45 155.0 56.6 2.1e-45 155.0 39.3 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ83563.1 - 8.3e-18 63.9 31.4 1.5e-17 63.0 21.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EAQ83563.1 - 1.7e-13 50.0 13.7 1.7e-13 50.0 9.5 3.3 3 1 1 4 4 4 2 Sugar (and other) transporter ATG22 PF11700.3 EAQ83563.1 - 2.6e-06 26.2 12.5 2.6e-06 26.2 8.7 3.8 3 2 0 3 3 3 2 Vacuole effluxer Atg22 like Halogen_Hydrol PF10112.4 EAQ83563.1 - 0.74 9.1 6.7 5.6 6.3 1.3 2.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF829 PF05705.9 EAQ83564.1 - 3.7e-20 72.6 0.1 2.2e-17 63.5 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic protein of unknown function (DUF829) Adeno_E3_CR2 PF02439.10 EAQ83565.1 - 0.00023 20.6 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EAQ83565.1 - 0.00081 19.7 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.2 EAQ83565.1 - 0.00081 17.6 0.1 0.0011 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) TMEM154 PF15102.1 EAQ83565.1 - 0.0039 16.9 0.0 0.0052 16.4 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.5 EAQ83565.1 - 0.0046 16.2 3.9 0.0072 15.6 2.7 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EAQ83565.1 - 0.0054 15.5 0.0 0.0063 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 EAQ83565.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 EAQ83565.1 - 0.027 14.6 0.2 0.059 13.5 0.1 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF3609 PF12259.3 EAQ83565.1 - 0.035 12.7 0.0 0.042 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF4366 PF14283.1 EAQ83565.1 - 0.044 13.1 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF912 PF06024.7 EAQ83565.1 - 0.048 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3481 PF11980.3 EAQ83565.1 - 0.079 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) DUF2207 PF09972.4 EAQ83565.1 - 0.17 10.4 0.0 0.21 10.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_S2 PF00318.15 EAQ83567.1 - 3.1e-49 167.0 0.0 5.6e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 EAQ83567.1 - 1e-40 137.1 8.4 6.4e-10 38.6 0.0 5.9 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 EAQ83567.1 - 2.6e-09 36.6 0.0 9.3e-09 34.8 0.0 2.0 2 0 0 2 2 2 1 PB1 domain FtsA PF14450.1 EAQ83567.1 - 0.086 12.6 0.0 1.6 8.5 0.0 2.9 3 1 0 3 3 3 0 Cell division protein FtsA DUF3464 PF11947.3 EAQ83567.1 - 1.5 8.2 6.3 0.49 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) zf-H2C2 PF09337.5 EAQ83568.1 - 2.4e-22 78.0 4.6 5.3e-22 76.9 3.2 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EAQ83568.1 - 2.7e-05 24.1 0.0 6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EAQ83568.1 - 0.00097 19.1 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAQ83568.1 - 0.011 15.8 0.1 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Imm47 PF15586.1 EAQ83568.1 - 0.024 14.4 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 47 Dicty_REP PF05086.7 EAQ83568.1 - 0.73 7.5 10.0 1.1 6.9 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cpn60_TCP1 PF00118.19 EAQ83569.1 - 1.3e-140 469.2 4.2 1.5e-140 469.0 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ank_2 PF12796.2 EAQ83570.1 - 2.9e-25 88.4 0.0 1.7e-13 50.7 0.0 5.9 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ83570.1 - 3.8e-18 64.2 10.1 1.1e-05 24.9 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EAQ83570.1 - 4.6e-15 54.2 0.5 0.028 14.6 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EAQ83570.1 - 8.2e-15 54.8 1.8 9.8e-08 32.3 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ83570.1 - 1e-14 54.1 3.6 0.00041 20.4 0.0 5.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EAQ83570.1 - 1.6e-07 30.9 0.0 6.1e-07 29.0 0.0 2.1 1 0 0 1 1 1 1 F-box-like DUF1012 PF06241.7 EAQ83570.1 - 0.3 10.6 0.0 0.52 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1012) Ribosomal_S26e PF01283.14 EAQ83572.1 - 2.7e-51 172.5 9.1 3.2e-51 172.3 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EAQ83572.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 EAQ83572.1 - 0.049 13.9 0.3 7.8 6.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EAQ83572.1 - 0.1 13.0 2.3 1.2 9.6 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain ubiquitin PF00240.18 EAQ83573.1 - 5.5e-35 118.5 0.9 6.3e-35 118.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAQ83573.1 - 2e-20 72.2 0.7 2.3e-20 72.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAQ83573.1 - 2.6e-06 27.5 0.2 9.9e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAQ83573.1 - 0.00033 20.4 0.0 0.00039 20.1 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAQ83573.1 - 0.0036 17.1 0.1 0.007 16.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAQ83573.1 - 0.0095 16.1 0.1 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EAQ83573.1 - 0.054 13.5 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EAQ83573.1 - 0.11 10.8 0.7 2.3 6.4 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EAQ83573.1 - 0.43 10.5 1.8 0.77 9.7 1.2 1.3 1 0 0 1 1 1 0 Tash protein PEST motif Glyco_hydro_18 PF00704.23 EAQ83574.1 - 2.3e-40 139.1 0.2 3.3e-32 112.2 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Polysacc_deac_1 PF01522.16 EAQ83575.1 - 5.9e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.20 EAQ83576.1 - 8.5e-62 208.6 0.0 1.4e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83576.1 - 1.7e-26 92.8 0.0 3.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EAQ83576.1 - 1.7e-25 89.1 2.2 3e-14 53.1 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ83576.1 - 6.5e-20 69.8 2.3 8.6e-05 22.1 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EAQ83576.1 - 2.8e-14 51.8 0.0 0.014 15.6 0.0 6.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EAQ83576.1 - 2.6e-13 49.7 2.8 1.4e-05 25.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ83576.1 - 4.9e-13 49.1 0.4 0.00013 22.3 0.1 4.0 2 1 2 4 4 3 3 Ankyrin repeats (many copies) NACHT PF05729.7 EAQ83576.1 - 2e-07 30.8 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Kinase-like PF14531.1 EAQ83576.1 - 7.4e-05 21.8 0.0 0.00022 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like AAA_16 PF13191.1 EAQ83576.1 - 0.00058 19.8 6.1 0.0017 18.3 0.2 2.9 2 1 1 3 3 2 1 AAA ATPase domain Kdo PF06293.9 EAQ83576.1 - 0.0014 17.6 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_33 PF13671.1 EAQ83576.1 - 0.002 18.0 0.0 0.037 13.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ83576.1 - 0.0046 17.0 0.1 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain APH PF01636.18 EAQ83576.1 - 0.02 14.6 1.3 0.33 10.6 0.9 2.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAQ83576.1 - 0.079 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase KAP_NTPase PF07693.9 EAQ83576.1 - 0.11 11.4 0.1 9.5 5.1 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain VASP_tetra PF08776.6 EAQ83576.1 - 0.12 11.6 0.5 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain DUF2075 PF09848.4 EAQ83576.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Annexin PF00191.15 EAQ83577.1 - 1.5e-50 168.9 5.5 4.2e-15 55.3 0.1 4.3 4 0 0 4 4 4 4 Annexin Apo-CII PF05355.6 EAQ83577.1 - 0.015 15.1 0.6 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein C-II ClpB_D2-small PF10431.4 EAQ83577.1 - 0.36 10.7 3.4 0.9 9.4 0.1 2.7 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein PIF1 PF05970.9 EAQ83579.1 - 0.00019 20.4 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ83579.1 - 0.0099 15.9 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF164 PF02591.10 EAQ83579.1 - 0.04 13.7 1.7 0.74 9.6 0.0 3.1 3 0 0 3 3 3 0 Putative zinc ribbon domain FKBP_N PF01346.13 EAQ83579.1 - 0.13 12.3 0.7 0.34 10.9 0.5 1.7 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Herpes_Helicase PF02689.9 EAQ83579.1 - 0.22 9.2 0.0 0.32 8.6 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF2576 PF10845.3 EAQ83579.1 - 0.62 9.2 2.3 19 4.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) DUF4473 PF14747.1 EAQ83580.1 - 0.056 13.6 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) YL1_C PF08265.6 EAQ83580.1 - 0.2 11.2 0.5 0.4 10.2 0.2 1.7 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain LVIVD PF08309.6 EAQ83581.1 - 1.3e-06 27.2 0.7 0.58 9.1 0.0 4.4 4 0 0 4 4 4 3 LVIVD repeat Beta_propel PF09826.4 EAQ83581.1 - 0.091 11.0 0.0 6.5 4.9 0.0 2.3 1 1 0 2 2 2 0 Beta propeller domain Adaptin_N PF01602.15 EAQ83582.1 - 3.9e-149 497.3 2.1 5.5e-149 496.8 1.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EAQ83582.1 - 1.4e-26 93.4 0.1 6.2e-26 91.3 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAQ83582.1 - 3.9e-17 62.3 0.1 5.3e-07 29.8 0.0 5.4 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EAQ83582.1 - 2.8e-11 42.4 5.3 0.0084 16.1 0.0 6.2 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EAQ83582.1 - 1e-05 25.8 0.5 1.9 9.0 0.0 5.5 5 1 0 5 5 5 1 HEAT-like repeat Arm PF00514.18 EAQ83582.1 - 0.00093 18.9 1.5 2.6 7.9 0.0 5.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 EAQ83582.1 - 0.013 15.1 0.6 0.17 11.5 0.1 2.6 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EAQ83582.1 - 0.021 14.1 0.1 2.2 7.5 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.4 EAQ83582.1 - 0.063 13.0 0.0 1.4 8.6 0.0 2.8 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain AF0941-like PF14591.1 EAQ83582.1 - 0.21 11.6 1.9 0.54 10.3 1.3 1.7 1 0 0 1 1 1 0 AF0941-like Asparaginase_2 PF01112.13 EAQ83584.1 - 2.1e-68 230.4 12.4 4.9e-36 124.0 2.3 2.9 2 1 1 3 3 3 2 Asparaginase p450 PF00067.17 EAQ83585.1 - 1.9e-53 181.6 0.0 2.5e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NMT1 PF09084.6 EAQ83588.1 - 2e-09 37.4 0.0 3.9e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EAQ83588.1 - 0.032 13.5 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Glyco_transf_20 PF00982.16 EAQ83589.1 - 7e-164 545.7 0.1 1.4e-85 287.5 0.0 3.0 1 1 2 3 3 3 3 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EAQ83589.1 - 0.074 12.5 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain MFS_1 PF07690.11 EAQ83590.1 - 9.1e-24 83.8 67.0 9e-22 77.2 43.2 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ83590.1 - 0.00018 20.0 0.3 0.00018 20.0 0.2 3.7 3 1 0 3 3 3 2 MFS/sugar transport protein Cu-oxidase_3 PF07732.10 EAQ83591.1 - 1.1e-11 44.4 0.1 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ83591.1 - 7.7e-09 35.1 0.0 0.0016 17.9 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EAQ83591.1 - 0.0047 16.8 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.15 EAQ83591.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family RVT_2 PF07727.9 EAQ83592.1 - 4.2e-13 48.8 0.0 7.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ83592.1 - 7.7e-09 35.6 0.0 2.2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ83592.1 - 1.7e-05 24.3 0.4 4.2e-05 23.0 0.3 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Rif1_N PF12231.3 EAQ83592.1 - 0.47 9.3 0.0 0.75 8.6 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Glyco_hydro_67M PF07488.7 EAQ83593.1 - 3.9e-152 505.8 0.0 5e-152 505.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EAQ83593.1 - 1.8e-91 305.5 0.8 3.7e-91 304.5 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EAQ83593.1 - 1.7e-28 99.0 0.0 3.2e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EAQ83593.1 - 0.004 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ADH_zinc_N_2 PF13602.1 EAQ83594.1 - 4e-11 43.9 0.0 8.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ83594.1 - 3.3e-08 33.2 0.6 1e-07 31.6 0.4 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ83594.1 - 3.3e-06 26.6 0.1 9.6e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF676 PF05057.9 EAQ83595.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) SDH_sah PF01972.11 EAQ83595.1 - 0.0022 16.8 0.2 0.035 12.8 0.0 2.6 3 0 0 3 3 3 1 Serine dehydrogenase proteinase PGAP1 PF07819.8 EAQ83595.1 - 0.0073 15.9 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein FAD_binding_4 PF01565.18 EAQ83599.1 - 4e-21 74.9 1.0 8.8e-21 73.8 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ83599.1 - 8.6e-12 44.7 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EAQ83599.1 - 0.22 10.6 0.1 0.33 10.0 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding KAR9 PF08580.5 EAQ83601.1 - 1.5 7.0 9.8 1.7 6.8 6.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF605 PF04652.11 EAQ83601.1 - 5.3 6.3 14.3 6.6 6.0 9.9 1.3 1 0 0 1 1 1 0 Vta1 like DUF3471 PF11954.3 EAQ83603.1 - 3.9e-07 29.8 0.1 5.9e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.19 EAQ83603.1 - 7.2e-06 25.2 0.1 1.1e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Bac_rhodopsin PF01036.13 EAQ83604.1 - 3.6e-41 140.9 18.5 4.4e-41 140.6 12.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3792 PF12670.2 EAQ83604.1 - 2.3 8.1 16.1 5.7 6.8 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) PP2C PF00481.16 EAQ83605.1 - 1.4e-16 60.6 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3262 PF11660.3 EAQ83605.1 - 0.029 14.4 0.2 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Apq12 PF12716.2 EAQ83606.1 - 1.3 8.7 5.1 3 7.6 3.5 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Gelsolin PF00626.17 EAQ83607.1 - 3.4e-23 81.1 0.0 1.4e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Gelsolin repeat Meth_synt_2 PF01717.13 EAQ83608.1 - 1.8e-16 60.0 0.0 2.4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EAQ83608.1 - 5.5e-05 22.5 0.0 0.015 14.6 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Sugar_tr PF00083.19 EAQ83609.1 - 4.6e-28 97.9 7.6 5e-28 97.8 5.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83612.1 - 1.2e-38 132.8 37.4 1.2e-38 132.8 25.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ83612.1 - 3.3e-08 32.5 27.3 1.9e-07 30.0 18.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter SAYSvFN PF10260.4 EAQ83612.1 - 0.093 12.5 0.4 0.35 10.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Ferritin_2 PF13668.1 EAQ83613.1 - 0.017 15.0 0.3 0.34 10.8 0.1 2.2 1 1 1 2 2 2 0 Ferritin-like domain Tri3 PF07428.6 EAQ83614.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 MFS_1 PF07690.11 EAQ83615.1 - 1.1e-27 96.7 35.0 1.3e-26 93.1 23.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ83615.1 - 1.1e-11 43.6 10.1 1.7e-11 43.0 7.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.3 EAQ83615.1 - 0.029 14.1 0.5 0.32 10.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) FAD_binding_4 PF01565.18 EAQ83616.1 - 2.3e-18 65.9 1.8 4.2e-18 65.1 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ83616.1 - 2.5e-06 27.2 0.0 5.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 EAQ83616.1 - 0.038 13.3 0.0 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain FAD_binding_3 PF01494.14 EAQ83617.1 - 6.5e-17 61.6 5.0 1.8e-08 33.8 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAQ83617.1 - 8.4e-08 31.4 0.8 1.5e-06 27.3 0.2 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ83617.1 - 0.0031 17.5 2.6 0.0033 17.4 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ83617.1 - 0.0053 16.6 0.1 0.0092 15.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ83617.1 - 0.0077 16.6 2.4 0.043 14.2 1.4 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ83617.1 - 0.0096 15.7 0.2 0.034 13.9 0.1 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAQ83617.1 - 0.011 15.8 1.0 0.16 11.9 0.7 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EAQ83617.1 - 0.011 15.3 0.4 0.02 14.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EAQ83617.1 - 0.013 14.2 1.1 0.24 9.9 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EAQ83617.1 - 0.023 13.5 1.8 0.034 13.0 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EAQ83617.1 - 0.043 13.1 0.2 0.071 12.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EAQ83617.1 - 0.11 12.2 0.2 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EAQ83617.1 - 0.17 12.3 1.1 0.43 11.0 0.8 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EAQ83619.1 - 4.6e-12 45.6 0.4 1.1e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ83619.1 - 0.00013 21.6 0.1 0.00032 20.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UCR_Fe-S_N PF10399.4 EAQ83620.1 - 0.29 10.3 2.1 0.54 9.4 1.5 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cu-oxidase_3 PF07732.10 EAQ83621.1 - 1.4e-41 140.9 5.3 1e-40 138.1 2.5 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ83621.1 - 4.1e-31 107.3 1.1 4.1e-31 107.3 0.8 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EAQ83621.1 - 1.9e-26 92.8 0.0 4.4e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Acyl_transf_1 PF00698.16 EAQ83623.1 - 9.1e-33 113.9 1.2 1.3e-32 113.4 0.1 1.7 2 0 0 2 2 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EAQ83623.1 - 1.4e-32 112.0 0.0 3.5e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EAQ83623.1 - 1.8e-32 112.8 0.2 2.6e-23 82.7 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EAQ83623.1 - 7.1e-22 77.5 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EAQ83623.1 - 1.8e-13 50.8 0.0 4.6e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ83623.1 - 2.6e-09 36.8 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ83623.1 - 8.7e-09 35.2 0.0 4.9e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EAQ83623.1 - 3.1e-08 33.7 0.1 7.9e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EAQ83623.1 - 2.1e-06 28.1 0.0 8.3e-06 26.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ83623.1 - 6.3e-06 26.7 0.0 2.5e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EAQ83623.1 - 8.2e-06 25.8 0.1 7.6e-05 22.6 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.13 EAQ83623.1 - 0.00019 20.6 0.0 0.00061 18.9 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family KR PF08659.5 EAQ83623.1 - 0.00034 20.3 1.7 0.0015 18.2 0.0 2.8 3 0 0 3 3 3 1 KR domain Methyltransf_26 PF13659.1 EAQ83623.1 - 0.0048 16.9 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EAQ83623.1 - 0.01 15.2 0.0 0.043 13.2 0.0 2.1 2 1 0 2 2 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ83623.1 - 0.026 13.4 0.0 2 7.2 0.0 2.6 3 0 0 3 3 3 0 RmlD substrate binding domain DREV PF05219.7 EAQ83623.1 - 0.053 12.3 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NmrA PF05368.8 EAQ83623.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RrnaAD PF00398.15 EAQ83623.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Polysacc_synt_2 PF02719.10 EAQ83623.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EAQ83623.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_32 PF13679.1 EAQ83623.1 - 0.19 11.3 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EAQ83623.1 - 0.39 10.1 0.0 0.87 9.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF1561 PF07598.6 EAQ83623.1 - 0.64 7.8 0.0 1 7.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Transferase PF02458.10 EAQ83624.1 - 1.8e-22 79.4 0.0 2.9e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Transferase family adh_short PF00106.20 EAQ83625.1 - 1.3e-22 80.5 1.2 1.7e-22 80.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ83625.1 - 5e-13 49.3 0.0 6.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ83625.1 - 2.4e-09 37.0 0.2 8.3e-09 35.3 0.3 1.7 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 EAQ83625.1 - 2.2e-05 23.8 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ83625.1 - 3.3e-05 23.9 0.3 5.4e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ83625.1 - 0.00047 19.6 0.0 0.00069 19.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ83625.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_N PF08240.7 EAQ83626.1 - 3.2e-07 30.0 0.0 6.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ83626.1 - 9.5e-07 28.4 1.1 1.7e-06 27.5 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EAQ83626.1 - 0.019 13.8 0.2 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain HpaP PF09483.5 EAQ83628.1 - 9.4 6.1 10.2 16 5.3 7.1 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DPBB_1 PF03330.13 EAQ83631.1 - 1.2e-11 44.4 0.2 3.7e-11 42.8 0.1 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EAQ83631.1 - 0.013 15.1 0.2 0.021 14.5 0.1 1.4 1 1 0 1 1 1 0 Barwin family Abhydrolase_1 PF00561.15 EAQ83632.1 - 2.1e-17 63.4 0.2 7.5e-16 58.3 0.2 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EAQ83632.1 - 7.9e-16 57.8 0.0 2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EAQ83632.1 - 3.6e-11 43.3 0.3 8.9e-11 42.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3593 PF12159.3 EAQ83634.1 - 0.3 10.9 5.7 4.7 7.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) DDE_1 PF03184.14 EAQ83635.1 - 3.8e-16 58.8 0.0 6.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ83635.1 - 4.1e-10 39.0 0.0 8.7e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ83635.1 - 2.6e-08 33.5 0.0 7.3e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ83635.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D RVT_1 PF00078.22 EAQ83638.1 - 1.1e-29 103.2 0.0 2e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_61 PF03443.9 EAQ83639.1 - 4.7e-74 248.8 2.4 6e-74 248.5 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.16 EAQ83640.1 - 1.8e-99 333.2 31.5 6.9e-50 169.7 1.2 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAQ83640.1 - 1.2e-26 93.2 31.5 1.2e-13 50.4 1.2 2.1 1 1 1 2 2 2 2 Amino acid permease DUF3959 PF13105.1 EAQ83641.1 - 0.11 11.8 0.4 0.2 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Kinesin PF00225.18 EAQ83642.1 - 3.6e-38 131.1 0.0 1.7e-33 115.7 0.0 2.1 1 1 1 2 2 2 2 Kinesin motor domain SAM_PNT PF02198.11 EAQ83642.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Amidohydro_4 PF13147.1 EAQ83644.1 - 3.1e-11 43.8 7.4 2.2e-08 34.4 0.0 3.6 3 0 0 3 3 3 3 Amidohydrolase Amidohydro_1 PF01979.15 EAQ83644.1 - 5.6e-06 26.2 1.1 0.00022 20.9 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 EAQ83644.1 - 1.4e-05 24.7 0.1 3.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EAQ83644.1 - 5e-05 22.7 0.4 0.00023 20.4 0.0 2.2 3 0 0 3 3 3 1 Amidohydrolase family Abhydrolase_2 PF02230.11 EAQ83647.1 - 4.8e-05 22.9 0.1 0.00043 19.7 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAQ83647.1 - 7.2e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EAQ83647.1 - 0.00052 19.5 0.5 0.0034 16.8 0.3 2.1 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EAQ83647.1 - 0.00055 19.2 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.13 EAQ83647.1 - 0.0071 15.6 0.4 0.21 10.8 0.0 2.1 1 1 1 2 2 2 1 Dienelactone hydrolase family Ecm33 PF12454.3 EAQ83647.1 - 0.011 15.5 0.7 0.027 14.3 0.5 1.7 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Abhydrolase_6 PF12697.2 EAQ83647.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ83647.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-XS PF03470.9 EAQ83648.1 - 0.32 11.0 0.2 0.32 11.0 0.1 2.5 2 0 0 2 2 2 0 XS zinc finger domain MFS_1 PF07690.11 EAQ83649.1 - 1.5e-05 23.9 12.7 1.5e-05 23.9 8.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Queuosine_synth PF02547.10 EAQ83650.1 - 1.5e-85 286.9 0.0 1.6e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein Aminotran_1_2 PF00155.16 EAQ83651.1 - 3e-42 144.8 0.0 4.4e-42 144.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II PhyH PF05721.8 EAQ83652.1 - 1.9e-18 67.2 0.3 5.8e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.23 EAQ83653.1 - 0 1624.1 9.9 7.6e-79 265.0 0.0 9.6 8 1 1 9 9 9 9 AMP-binding enzyme Condensation PF00668.15 EAQ83653.1 - 0 1183.0 0.2 1.3e-43 148.9 0.0 15.1 12 5 1 13 13 13 12 Condensation domain PP-binding PF00550.20 EAQ83653.1 - 1.1e-85 281.8 0.1 1.1e-12 48.0 0.0 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EAQ83653.1 - 0.004 17.4 0.7 0.28 11.5 0.0 3.9 3 0 0 3 3 3 1 HxxPF-repeated domain AATase PF07247.7 EAQ83653.1 - 2.2 6.7 0.0 11 4.4 0.0 2.2 1 0 0 1 1 1 0 Alcohol acetyltransferase DUF3255 PF11631.3 EAQ83653.1 - 5.4 6.6 0.1 15 5.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) Glyco_hydro_31 PF01055.21 EAQ83656.1 - 3.1e-160 533.8 3.8 4.1e-160 533.4 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAQ83656.1 - 2.9e-08 33.4 0.7 2.9e-08 33.4 0.5 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Pec_lyase_C PF00544.14 EAQ83657.1 - 2.7e-41 141.2 6.1 4.2e-41 140.6 4.2 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EAQ83657.1 - 0.00094 18.9 7.1 0.013 15.3 4.9 2.1 1 1 0 1 1 1 1 Right handed beta helix region PMI_typeI PF01238.16 EAQ83658.1 - 1.7e-66 224.7 0.0 2.4e-65 220.9 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_4 PF08007.7 EAQ83658.1 - 0.11 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein DUF3292 PF11696.3 EAQ83659.1 - 8e-150 499.7 8.6 4.5e-99 332.0 0.0 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) NAD_binding_1 PF00175.16 EAQ83661.1 - 6.4e-19 68.5 0.1 1.6e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EAQ83661.1 - 5.6e-06 26.4 0.0 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Bromo_TP PF07524.8 EAQ83661.1 - 0.033 13.9 0.1 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF605 PF04652.11 EAQ83661.1 - 0.092 12.1 14.5 0.12 11.7 10.0 1.1 1 0 0 1 1 1 0 Vta1 like Oxidored_molyb PF00174.14 EAQ83662.1 - 4.3e-30 104.3 0.0 2.5e-29 101.8 0.0 2.0 1 1 1 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EAQ83662.1 - 2e-09 37.1 0.1 4e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF4407 PF14362.1 EAQ83662.1 - 1.2 8.0 4.3 1.8 7.4 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 EAQ83662.1 - 5.6 6.9 14.2 9.8 6.1 9.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 An_peroxidase PF03098.10 EAQ83663.1 - 8.7e-84 281.7 0.0 4.4e-49 167.2 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase DUF2235 PF09994.4 EAQ83664.1 - 1.7e-108 362.2 0.2 2.3e-108 361.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AAA_12 PF13087.1 EAQ83665.1 - 4.5e-33 114.3 0.0 7.7e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAQ83665.1 - 6.5e-25 88.0 0.0 1.3e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ83665.1 - 1.1e-06 28.2 0.6 4.4e-06 26.3 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain DUF2075 PF09848.4 EAQ83665.1 - 9.3e-06 24.8 0.0 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EAQ83665.1 - 0.0014 18.6 0.0 0.0083 16.1 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EAQ83665.1 - 0.0054 16.3 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 EAQ83665.1 - 0.022 14.8 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 EAQ83665.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CytochromB561_N PF09786.4 EAQ83667.1 - 0.82 8.0 4.1 10 4.4 2.0 2.0 1 1 1 2 2 2 0 Cytochrome B561, N terminal Peptidase_S64 PF08192.6 EAQ83668.1 - 0.04 12.2 0.0 0.056 11.7 0.0 1.3 1 1 0 1 1 1 0 Peptidase family S64 Peptidase_S32 PF05579.8 EAQ83668.1 - 0.054 12.4 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Chitin_bind_1 PF00187.14 EAQ83669.1 - 0.027 14.4 23.4 0.027 14.4 16.2 5.0 5 0 0 5 5 5 0 Chitin recognition protein TRAM1 PF08390.6 EAQ83670.1 - 7.9e-25 86.1 0.1 7.9e-25 86.1 0.1 2.1 2 1 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 EAQ83670.1 - 1.1e-24 87.1 14.4 6.3e-23 81.3 10.0 2.4 1 1 0 1 1 1 1 TLC domain Adeno_E3_CR2 PF02439.10 EAQ83671.1 - 0.29 10.7 0.0 0.46 10.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 EAQ83671.1 - 0.31 10.6 0.0 0.45 10.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Syndecan PF01034.15 EAQ83671.1 - 0.32 10.6 0.3 0.6 9.8 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EAQ83671.1 - 3.6 6.9 6.9 8.5 5.7 4.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 EAQ83671.1 - 3.9 7.6 0.0 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Baculo_PEP_C PF04513.7 EAQ83672.1 - 0.017 14.9 0.3 0.029 14.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellin_N PF00669.15 EAQ83672.1 - 0.054 13.2 1.4 0.081 12.7 0.1 1.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Dmrt1 PF12374.3 EAQ83673.1 - 0.065 13.5 0.6 0.86 9.9 0.2 2.1 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 p450 PF00067.17 EAQ83674.1 - 8.7e-34 116.8 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_8 PF13450.1 EAQ83676.1 - 1.4e-13 50.6 0.0 1.4e-13 50.6 0.0 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EAQ83676.1 - 2.4e-05 23.6 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EAQ83676.1 - 5.5e-05 22.1 1.0 9.3e-05 21.4 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ83676.1 - 0.00012 21.1 0.5 0.0002 20.3 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ83676.1 - 0.00018 20.1 0.4 0.00027 19.5 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EAQ83676.1 - 0.00025 20.2 0.2 0.00038 19.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ83676.1 - 0.0013 18.6 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ83676.1 - 0.0028 17.7 0.1 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ83676.1 - 0.0037 17.0 0.1 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EAQ83676.1 - 0.024 13.7 0.2 0.041 12.9 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EAQ83676.1 - 0.043 12.4 0.2 0.071 11.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EAQ83676.1 - 0.077 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ83676.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ETS_PEA3_N PF04621.8 EAQ83677.1 - 0.75 8.9 3.4 1.2 8.3 2.3 1.4 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain DUF3080 PF11279.3 EAQ83678.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) PHO4 PF01384.15 EAQ83679.1 - 5e-42 143.7 0.0 9.3e-14 50.8 5.7 4.1 3 1 1 4 4 4 4 Phosphate transporter family Peptidase_S8 PF00082.17 EAQ83682.1 - 2.8e-49 167.7 11.2 5.1e-49 166.9 7.7 1.4 1 0 0 1 1 1 1 Subtilase family Type_III_YscG PF09477.5 EAQ83682.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Inhibitor_I9 PF05922.11 EAQ83682.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Oxidored_FMN PF00724.15 EAQ83684.1 - 6.5e-66 222.6 0.0 7.7e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EAQ83684.1 - 0.035 12.9 0.0 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Spt20 PF12090.3 EAQ83685.1 - 0.0039 16.5 0.8 0.0039 16.5 0.6 1.1 1 0 0 1 1 1 1 Spt20 family Peptidase_S49_N PF08496.5 EAQ83685.1 - 0.22 11.3 3.3 0.36 10.6 2.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF106 PF01956.11 EAQ83685.1 - 0.22 11.0 2.2 0.31 10.5 1.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FimP PF09766.4 EAQ83685.1 - 2.4 7.1 14.3 3.1 6.7 9.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein ERK-JNK_inhib PF15002.1 EAQ83685.1 - 3.9 6.7 10.1 5.4 6.3 7.0 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Baculo_PP31 PF05311.6 EAQ83685.1 - 6.8 5.8 7.9 9.3 5.4 5.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pyr_redox_3 PF13738.1 EAQ83686.1 - 6.3e-18 65.5 0.0 6.7e-17 62.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ83686.1 - 4.9e-07 28.3 0.7 0.33 9.0 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAQ83686.1 - 1.9e-06 27.9 0.0 0.0038 17.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ83686.1 - 4e-06 26.7 0.0 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EAQ83686.1 - 1.4e-05 24.2 0.1 0.045 12.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EAQ83686.1 - 1.5e-05 24.1 0.0 3.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EAQ83686.1 - 9e-05 22.8 0.3 0.54 10.7 0.0 3.3 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ83686.1 - 0.00034 19.1 0.4 0.0019 16.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EAQ83686.1 - 0.001 18.2 0.0 0.027 13.5 0.0 2.5 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.1 EAQ83686.1 - 0.0016 18.2 0.1 0.55 9.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 EAQ83686.1 - 0.0045 15.8 0.7 0.051 12.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EAQ83686.1 - 0.0095 14.8 0.0 0.098 11.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EAQ83686.1 - 0.013 15.5 0.1 4.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EAQ83686.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ83686.1 - 0.02 13.7 0.1 0.03 13.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EAQ83686.1 - 0.097 12.3 0.1 6.1 6.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAQ83686.1 - 0.1 12.6 0.0 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain ketoacyl-synt PF00109.21 EAQ83688.1 - 4.8e-78 262.1 0.0 1e-77 261.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ83688.1 - 6.7e-48 163.6 0.0 1.3e-47 162.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAQ83688.1 - 1.9e-45 155.3 0.0 5.5e-45 153.7 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 EAQ83688.1 - 1.8e-36 125.5 0.0 5.7e-36 123.8 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 EAQ83688.1 - 3.9e-35 120.2 0.0 9.5e-35 119.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EAQ83688.1 - 5.9e-30 104.3 0.6 3.5e-29 101.8 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.20 EAQ83688.1 - 0.00012 22.2 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EAQ83688.1 - 0.039 12.9 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Globin PF00042.17 EAQ83690.1 - 6.6e-08 32.8 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 EAQ83690.1 - 4.7e-07 29.8 0.0 9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 EAQ83690.1 - 5.9e-05 22.7 0.1 0.00014 21.5 0.1 1.7 1 1 0 1 1 1 1 Protoglobin NAD_binding_1 PF00175.16 EAQ83690.1 - 0.00039 20.9 0.0 0.00072 20.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Thymidylat_synt PF00303.14 EAQ83692.1 - 1.3e-115 385.0 0.0 1.5e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Glycos_transf_1 PF00534.15 EAQ83693.1 - 3.1e-22 78.8 0.0 1.1e-21 76.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAQ83693.1 - 2.3e-09 37.5 0.0 6.5e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EAQ83693.1 - 0.00038 20.6 0.0 0.0031 17.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Haem_bd PF14376.1 EAQ83693.1 - 0.079 12.6 0.2 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Haem-binding domain Sod_Fe_N PF00081.17 EAQ83694.1 - 8.2e-31 106.0 0.7 1.1e-30 105.7 0.5 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EAQ83694.1 - 0.00013 21.8 0.2 0.00026 20.7 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sld5 PF05916.6 EAQ83695.1 - 2.8e-12 46.8 0.0 1.5e-11 44.5 0.0 1.9 1 1 1 2 2 2 1 GINS complex protein Methyltransf_24 PF13578.1 EAQ83695.1 - 0.14 12.9 0.1 0.62 10.9 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain BATS PF06968.8 EAQ83696.1 - 1.3e-30 105.1 0.2 5.4e-30 103.0 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EAQ83696.1 - 1.3e-16 61.2 0.1 2.6e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF3405 PF11885.3 EAQ83698.1 - 1.3e-153 511.8 3.9 1.5e-153 511.6 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Helicase_C PF00271.26 EAQ83699.1 - 6.7e-08 32.2 0.0 6.7e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ83699.1 - 0.00022 21.1 0.1 0.075 12.8 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EAQ83699.1 - 0.00069 19.1 0.2 0.0019 17.6 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Neur PF00064.13 EAQ83699.1 - 0.15 10.1 0.1 0.22 9.5 0.1 1.1 1 0 0 1 1 1 0 Neuraminidase IncA PF04156.9 EAQ83700.1 - 0.00092 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 IncA protein HTH_38 PF13936.1 EAQ83700.1 - 0.0072 15.8 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DUF433 PF04255.9 EAQ83700.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Nop14 PF04147.7 EAQ83700.1 - 2.3 6.0 7.4 2.5 5.8 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_LMP1 PF05297.6 EAQ83700.1 - 7.9 5.2 7.7 10 4.8 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2457 PF10446.4 EAQ83700.1 - 8.7 4.9 16.5 12 4.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aldose_epim PF01263.15 EAQ83702.1 - 8.6e-55 185.9 0.2 1e-54 185.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FA_hydroxylase PF04116.8 EAQ83703.1 - 3.5e-16 59.6 22.4 3.5e-16 59.6 15.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ank_2 PF12796.2 EAQ83704.1 - 1.8e-18 66.6 0.0 1.5e-09 38.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ83704.1 - 5.6e-18 64.9 0.7 0.00011 22.6 0.0 5.7 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ83704.1 - 8.2e-13 48.1 0.5 1.3e-06 28.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EAQ83704.1 - 1e-12 47.1 0.7 7.9e-06 25.4 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EAQ83704.1 - 5.8e-09 35.3 0.2 0.0035 17.4 0.1 4.6 4 0 0 4 4 3 2 Ankyrin repeat NACHT PF05729.7 EAQ83704.1 - 5.2e-08 32.7 0.0 5.8e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain PGAP1 PF07819.8 EAQ83704.1 - 4.2e-05 23.2 0.0 9.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 EAQ83704.1 - 6.5e-05 23.0 0.0 0.00039 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 EAQ83704.1 - 7.4e-05 22.7 1.0 7.4e-05 22.7 0.7 3.1 3 1 0 3 3 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EAQ83704.1 - 0.00012 21.3 0.0 0.00036 19.8 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 EAQ83704.1 - 0.00023 21.2 0.0 0.004 17.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EAQ83704.1 - 0.0034 17.5 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EAQ83704.1 - 0.0066 15.4 0.4 0.056 12.4 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain LCAT PF02450.10 EAQ83704.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EAQ83704.1 - 0.023 14.3 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) RNA_helicase PF00910.17 EAQ83704.1 - 0.043 13.9 0.1 0.32 11.2 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_29 PF13555.1 EAQ83704.1 - 0.052 13.0 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EAQ83704.1 - 0.062 12.6 0.3 0.5 9.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 EAQ83704.1 - 0.087 12.5 0.1 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_10 PF12846.2 EAQ83704.1 - 0.089 12.2 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 EAQ83704.1 - 0.12 11.2 0.0 0.95 8.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 EAQ83704.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF900 PF05990.7 EAQ83704.1 - 0.14 11.4 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) MoeA_N PF03453.12 EAQ83705.1 - 0.0027 17.0 1.3 0.0047 16.2 0.9 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) DUF4414 PF14377.1 EAQ83705.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) AAA PF00004.24 EAQ83706.1 - 3.1e-06 27.3 0.0 6.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Dicty_REP PF05086.7 EAQ83706.1 - 2 6.0 7.5 3 5.4 5.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4141 PF13605.1 EAQ83707.1 - 0.12 11.6 1.1 0.57 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) COesterase PF00135.23 EAQ83708.1 - 3.7e-84 283.3 0.0 7.1e-84 282.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ83708.1 - 3.8e-08 33.1 0.0 1e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ83708.1 - 0.00025 20.3 0.2 0.0004 19.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ83708.1 - 0.00052 19.7 0.0 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EAQ83708.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2920 PF11144.3 EAQ83708.1 - 0.31 10.0 0.0 0.45 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) FA_desaturase PF00487.19 EAQ83709.1 - 4.3e-41 141.0 22.3 6.3e-41 140.5 15.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EAQ83709.1 - 6.3e-10 38.7 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.2 EAQ83709.1 - 0.021 14.4 0.4 0.049 13.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3821) B12D PF06522.6 EAQ83710.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3638 PF12340.3 EAQ83711.1 - 1.5e-87 292.3 0.1 3.3e-87 291.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EAQ83711.1 - 3.2e-17 61.3 1.0 6.5e-17 60.3 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PP2C_C PF07830.8 EAQ83711.1 - 0.092 12.8 0.1 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain OS-D PF03392.8 EAQ83711.1 - 0.18 11.7 0.1 0.72 9.8 0.1 2.0 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Poxvirus PF06227.7 EAQ83711.1 - 0.4 10.2 0.1 0.71 9.4 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus Dicty_CAR PF05462.6 EAQ83712.1 - 1.7e-13 50.1 6.1 1.7e-13 50.1 4.2 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EAQ83712.1 - 2.3e-10 40.3 9.5 2.3e-10 40.3 6.6 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EAQ83712.1 - 2.3e-05 23.6 4.9 4.2e-05 22.8 3.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_transf_36 PF06165.6 EAQ83715.1 - 5.8e-20 71.1 0.0 1.2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 EAQ83715.1 - 7.6e-08 31.9 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family Bac_rhamnosid PF05592.6 EAQ83715.1 - 0.036 12.2 0.0 0.07 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase MULE PF10551.4 EAQ83716.1 - 8.9e-19 67.4 0.0 1.5e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ83716.1 - 0.0066 15.0 0.0 0.0084 14.7 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DUF3440 PF11922.3 EAQ83716.1 - 0.031 13.8 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Esterase_phd PF10503.4 EAQ83718.1 - 6.1e-23 81.2 1.3 1.2e-22 80.2 0.9 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EAQ83718.1 - 1.9e-08 33.7 0.3 4.8e-08 32.4 0.2 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.13 EAQ83718.1 - 3.2e-08 33.0 8.1 9.7e-08 31.5 5.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 EAQ83718.1 - 2.3e-07 30.6 1.2 4e-07 29.8 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAQ83718.1 - 0.0019 17.7 0.3 0.0032 17.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ83718.1 - 0.0041 17.0 4.0 0.013 15.3 2.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EAQ83722.1 - 9.9e-08 31.7 12.7 1.4e-07 31.3 8.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cript PF10235.4 EAQ83722.1 - 0.21 11.9 6.6 0.37 11.1 4.6 1.4 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DUF2039 PF10217.4 EAQ83722.1 - 0.4 10.7 8.3 0.63 10.0 5.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Methyltransf_11 PF08241.7 EAQ83723.1 - 1.2e-11 44.9 0.0 1.5e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ83723.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ83723.1 - 3.4e-09 36.9 0.0 1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ83723.1 - 3.3e-08 33.8 0.0 9.7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ83723.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ83723.1 - 1.4e-07 32.0 0.0 2.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ83723.1 - 7.5e-05 22.7 0.1 0.00067 19.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAQ83723.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EAQ83723.1 - 0.006 15.7 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 EAQ83723.1 - 0.037 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase ketoacyl-synt PF00109.21 EAQ83724.1 - 7.8e-63 212.3 0.1 2.1e-62 210.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAQ83724.1 - 3.1e-37 127.0 0.1 7.6e-37 125.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EAQ83724.1 - 7.7e-24 84.5 0.6 2.1e-23 83.1 0.4 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAQ83724.1 - 3.8e-21 75.5 0.1 1.1e-20 73.9 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.20 EAQ83724.1 - 6.3e-16 58.4 3.8 6.3e-09 35.9 0.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 EAQ83724.1 - 7.8e-14 51.7 0.0 1.3e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 EAQ83724.1 - 2.2e-12 47.3 0.0 1.1e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.16 EAQ83724.1 - 3.8e-10 39.3 0.0 2e-07 30.4 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ83724.1 - 4.9e-07 29.5 0.4 2.7e-05 23.9 0.0 3.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_26 PF13659.1 EAQ83724.1 - 0.00025 21.0 0.8 0.019 15.0 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ83724.1 - 0.00028 20.5 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ83724.1 - 0.0016 18.8 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Peripla_BP_1 PF00532.16 EAQ83724.1 - 0.0066 15.6 0.1 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family DLH PF01738.13 EAQ83724.1 - 0.0068 15.7 0.0 0.092 12.0 0.0 2.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Methyltransf_16 PF10294.4 EAQ83724.1 - 0.011 15.1 0.0 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Abhydrolase_2 PF02230.11 EAQ83724.1 - 0.011 15.1 0.0 0.72 9.2 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_18 PF12847.2 EAQ83724.1 - 0.016 15.7 0.0 0.1 13.1 0.0 2.5 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EAQ83724.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Plant_tran PF04827.9 EAQ83724.1 - 0.22 10.8 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Plant transposon protein COesterase PF00135.23 EAQ83724.1 - 0.44 9.1 0.0 0.84 8.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family FAD_binding_3 PF01494.14 EAQ83725.1 - 7.1e-63 212.7 0.0 1.6e-60 205.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ83725.1 - 0.0022 16.9 0.1 0.23 10.3 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ83725.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ83725.1 - 0.0081 16.2 0.1 0.028 14.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ83725.1 - 0.023 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EAQ83725.1 - 0.047 12.5 0.2 2.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAQ83725.1 - 0.065 13.2 0.1 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAQ83725.1 - 0.091 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ83725.1 - 0.11 11.3 0.1 2 7.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Myb_DNA-binding PF00249.26 EAQ83727.1 - 4e-16 58.7 1.1 8e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ83727.1 - 1.5e-12 47.4 1.0 3.9e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain NAD_binding_10 PF13460.1 EAQ83728.1 - 2.1e-10 40.9 1.7 3.1e-10 40.3 1.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ83728.1 - 3.2e-08 33.2 0.1 2.8e-07 30.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EAQ83728.1 - 0.00017 20.9 0.1 0.00046 19.5 0.3 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EAQ83728.1 - 0.00086 18.0 0.0 0.0049 15.6 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAQ83728.1 - 0.004 17.0 1.3 0.0077 16.1 0.9 1.6 1 0 0 1 1 1 1 short chain dehydrogenase CbiJ PF02571.9 EAQ83728.1 - 0.004 16.5 1.6 0.0064 15.8 1.1 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK TrkA_N PF02254.13 EAQ83728.1 - 0.0049 16.8 0.2 0.0082 16.1 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EAQ83728.1 - 0.0067 16.1 2.3 0.0074 15.9 0.8 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EAQ83728.1 - 0.05 12.5 0.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 EAQ83728.1 - 0.059 12.2 0.0 0.086 11.7 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Aconitase_B_N PF11791.3 EAQ83728.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain p450 PF00067.17 EAQ83729.1 - 1.7e-62 211.5 0.0 2.1e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EAQ83730.1 - 5.6e-25 87.7 52.1 7.4e-25 87.3 31.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ83730.1 - 0.026 14.3 5.4 0.41 10.4 0.1 3.7 3 1 1 4 4 4 0 MFS_1 like family Sugar_tr PF00083.19 EAQ83730.1 - 2.5 6.5 36.1 0.035 12.7 8.5 2.6 2 0 0 2 2 2 0 Sugar (and other) transporter NAD_binding_4 PF07993.7 EAQ83731.1 - 5.5e-29 100.8 0.0 7.9e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EAQ83731.1 - 1.3e-11 43.5 0.0 2.5e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EAQ83731.1 - 2.3e-09 37.0 0.0 9.6e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EAQ83731.1 - 1.4e-05 25.2 0.0 3.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EAQ83731.1 - 0.061 13.2 0.2 0.2 11.5 0.2 2.0 1 1 0 1 1 1 0 short chain dehydrogenase CBM_1 PF00734.13 EAQ83733.1 - 3.8e-13 48.8 10.5 3.8e-13 48.8 7.3 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 EAQ83733.1 - 4.8e-13 49.4 0.4 7.3e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RGS PF00615.14 EAQ83734.1 - 1.4e-07 31.5 0.0 3.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Regulator of G protein signaling domain Kelch_4 PF13418.1 EAQ83737.1 - 0.1 12.3 0.4 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain PH_10 PF15411.1 EAQ83740.1 - 4.4e-45 152.5 0.1 8.4e-45 151.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EAQ83740.1 - 4.8e-33 114.5 0.1 8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EAQ83740.1 - 7.9e-33 112.3 0.0 1.6e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EAQ83740.1 - 3.2e-08 33.0 0.0 6.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 EAQ83741.1 - 3.7e-39 131.2 9.2 7.4e-08 31.9 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EAQ83741.1 - 0.0001 20.6 0.2 0.08 11.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MgtE_N PF03448.12 EAQ83741.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Snf7 PF03357.16 EAQ83742.1 - 4.8e-43 146.4 11.9 5.7e-43 146.2 8.2 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 EAQ83742.1 - 0.007 16.5 8.5 1.4 9.1 0.0 3.4 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.1 EAQ83742.1 - 0.0087 15.5 8.3 0.013 14.9 5.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) FlxA PF14282.1 EAQ83742.1 - 0.012 15.5 11.0 0.012 15.5 7.6 1.8 1 1 1 2 2 2 0 FlxA-like protein COG2 PF06148.6 EAQ83742.1 - 0.018 14.9 2.0 0.018 14.9 1.4 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rogdi_lz PF10259.4 EAQ83742.1 - 0.027 13.5 2.6 0.054 12.5 0.8 1.8 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein Reo_sigmaC PF04582.7 EAQ83742.1 - 0.03 13.5 5.3 0.55 9.3 0.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EAQ83742.1 - 0.038 14.1 10.0 0.082 13.0 2.0 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Alpha-2-MRAP_C PF06401.6 EAQ83742.1 - 0.048 13.5 2.3 0.052 13.3 0.8 1.6 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain TBPIP PF07106.8 EAQ83742.1 - 0.067 12.7 12.2 1.9 7.9 0.8 3.1 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1569 PF07606.6 EAQ83742.1 - 0.098 12.5 0.5 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) CENP-F_leu_zip PF10473.4 EAQ83742.1 - 0.11 12.4 11.5 5.1 6.9 7.3 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NuA4 PF09340.5 EAQ83742.1 - 0.11 12.1 1.1 0.24 11.0 0.7 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 OmpH PF03938.9 EAQ83742.1 - 0.14 12.0 15.3 1 9.3 8.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Sec34 PF04136.10 EAQ83742.1 - 0.16 11.6 6.3 1.9 8.1 2.1 2.2 1 1 1 2 2 2 0 Sec34-like family Prefoldin_2 PF01920.15 EAQ83742.1 - 0.22 11.2 11.9 0.81 9.4 0.0 3.7 2 1 1 3 3 3 0 Prefoldin subunit AAA_13 PF13166.1 EAQ83742.1 - 0.51 8.7 7.9 1.3 7.3 5.5 1.6 1 1 0 1 1 1 0 AAA domain DUF2205 PF10224.4 EAQ83742.1 - 0.52 9.9 6.1 3.9 7.1 1.9 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Mnd1 PF03962.10 EAQ83742.1 - 0.52 9.9 11.5 1.9 8.1 7.1 2.2 1 1 1 2 2 2 0 Mnd1 family DUF342 PF03961.8 EAQ83742.1 - 1 7.7 8.4 4.1 5.6 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4337 PF14235.1 EAQ83742.1 - 1.5 8.6 7.5 0.37 10.6 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) IncA PF04156.9 EAQ83742.1 - 1.5 8.3 13.1 9.5 5.7 3.9 2.7 1 1 1 2 2 2 0 IncA protein DUF4140 PF13600.1 EAQ83742.1 - 2.1 8.8 9.8 4.9 7.6 0.0 3.8 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) MitMem_reg PF13012.1 EAQ83742.1 - 2.2 8.3 6.8 20 5.3 4.7 2.3 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Mod_r PF07200.8 EAQ83742.1 - 2.3 8.1 11.8 1.5 8.7 5.1 2.3 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.1 EAQ83742.1 - 2.7 6.8 8.6 2 7.3 4.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 EAQ83742.1 - 4.8 6.0 12.1 0.88 8.4 6.1 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EAQ83742.1 - 4.8 7.5 9.6 4.2e+02 1.3 6.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) NmrA PF05368.8 EAQ83743.1 - 7.8e-23 80.9 0.0 9.4e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ83743.1 - 2e-13 50.7 0.1 2.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ83743.1 - 0.0019 17.7 0.0 0.0095 15.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ83743.1 - 0.064 11.9 0.0 0.3 9.7 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Beta-lactamase PF00144.19 EAQ83745.1 - 5.1e-44 150.6 0.6 7.5e-44 150.0 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase Dimer_Tnp_hAT PF05699.9 EAQ83747.1 - 5.5e-15 54.7 0.1 1.3e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PmoA PF14100.1 EAQ83754.1 - 0.084 12.0 0.1 0.097 11.8 0.1 1.0 1 0 0 1 1 1 0 Methane oxygenase PmoA RabGAP-TBC PF00566.13 EAQ83758.1 - 1.4e-46 158.6 0.1 5.3e-45 153.5 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CCDC155 PF14662.1 EAQ83758.1 - 0.24 10.9 29.8 0.42 10.1 6.6 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 Microtub_assoc PF07989.6 EAQ83758.1 - 3.4 7.5 18.5 2.6 7.9 1.6 3.8 2 1 1 3 3 3 0 Microtubule associated Nup54 PF13874.1 EAQ83758.1 - 5.1 6.7 18.6 5.8 6.5 4.2 2.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 HALZ PF02183.13 EAQ83758.1 - 9 6.1 26.3 0.054 13.2 0.4 4.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper Ribosomal_S8e PF01201.17 EAQ83759.1 - 4.4e-49 166.0 1.3 5.1e-49 165.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.7 EAQ83760.1 - 7.3e-140 466.0 0.0 7.3e-140 466.0 0.0 4.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EAQ83760.1 - 5.8e-99 331.5 0.0 5.8e-99 331.5 0.0 3.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.20 EAQ83760.1 - 1.9e-77 260.5 0.6 6.9e-61 206.1 0.0 3.3 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EAQ83760.1 - 1.7e-32 111.5 7.7 1.7e-32 111.5 5.3 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF4414) Ribosomal_S6e PF01092.14 EAQ83761.1 - 5.6e-58 194.0 0.0 1.1e-57 193.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.4 EAQ83761.1 - 2.1 7.1 8.0 2.6 6.8 5.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Diphthamide_syn PF01866.12 EAQ83762.1 - 2.9e-106 355.1 0.0 3.4e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ctf8 PF09696.5 EAQ83763.1 - 2.1e-20 72.7 0.0 2.7e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Aldose_epim PF01263.15 EAQ83764.1 - 2.4e-49 168.0 0.1 3.7e-49 167.4 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase PGPGW PF09656.5 EAQ83764.1 - 0.047 12.9 1.2 0.079 12.2 0.8 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) ATP-synt_ab PF00006.20 EAQ83765.1 - 4.4e-38 130.9 0.0 4.2e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAQ83765.1 - 2.9e-16 59.9 0.1 5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Pro_isomerase PF00160.16 EAQ83766.1 - 3.9e-40 137.6 0.0 7.2e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Succ_DH_flav_C PF02910.15 EAQ83766.1 - 0.05 13.4 0.5 0.095 12.5 0.0 1.7 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term HSF_DNA-bind PF00447.12 EAQ83767.1 - 5.6e-28 97.1 0.2 1.3e-27 96.0 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.16 EAQ83768.1 - 1.9e-42 145.1 0.0 2.2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GGDEF PF00990.16 EAQ83768.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 GGDEF domain Arrestin_C PF02752.17 EAQ83769.1 - 8e-14 51.9 0.0 8.7e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 EAQ83770.1 - 2.5e-11 42.8 0.5 6e-11 41.6 0.3 1.7 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EAQ83770.1 - 0.049 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain K_channel_TID PF07941.6 EAQ83771.1 - 3 8.1 12.2 1 9.6 5.6 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-ZPR1 PF03367.8 EAQ83772.1 - 5.4e-102 337.7 0.6 1.1e-51 174.2 0.3 2.6 2 1 0 2 2 2 2 ZPR1 zinc-finger domain DUF866 PF05907.8 EAQ83773.1 - 4e-23 81.6 0.1 4.1e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) GDPD PF03009.12 EAQ83775.1 - 6.4e-65 219.1 0.0 1.6e-63 214.5 0.0 2.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EAQ83775.1 - 4.9e-32 110.1 0.3 2.1e-12 47.2 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) SPX PF03105.14 EAQ83775.1 - 5.5e-30 105.0 4.1 1.4e-17 64.4 0.4 3.6 2 1 1 3 3 3 2 SPX domain Ank_4 PF13637.1 EAQ83775.1 - 2.3e-29 101.2 0.8 8.1e-10 38.9 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EAQ83775.1 - 1.2e-26 91.0 2.9 6.2e-08 32.0 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EAQ83775.1 - 2.4e-23 81.6 1.4 8.8e-07 28.9 0.0 5.7 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ83775.1 - 6.4e-16 56.8 0.1 0.00017 21.5 0.0 5.5 4 0 0 4 4 4 3 Ankyrin repeat DUF3439 PF11921.3 EAQ83775.1 - 0.022 14.5 16.3 0.061 13.0 11.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TraD PF06412.6 EAQ83775.1 - 0.053 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Conjugal transfer protein TraD Dicty_REP PF05086.7 EAQ83775.1 - 3.5 5.2 8.5 5.3 4.6 5.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WW PF00397.21 EAQ83776.1 - 2.7e-06 27.1 0.1 5.6e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 WW domain Pga1 PF10333.4 EAQ83777.1 - 0.03 13.9 0.3 0.13 11.8 0.0 2.3 2 1 0 2 2 2 0 GPI-Mannosyltransferase II co-activator Remorin_N PF03766.8 EAQ83777.1 - 0.082 12.6 0.6 0.16 11.7 0.4 1.4 1 0 0 1 1 1 0 Remorin, N-terminal region ABC_membrane_2 PF06472.10 EAQ83778.1 - 1.4e-104 349.2 2.8 2.3e-104 348.4 1.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EAQ83778.1 - 2e-17 63.7 0.0 4.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAQ83778.1 - 0.0005 20.1 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ83778.1 - 0.012 15.6 0.4 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EAQ83778.1 - 0.037 13.5 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EAQ83778.1 - 0.059 12.6 0.1 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAQ83778.1 - 0.1 12.9 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain G_glu_transpept PF01019.16 EAQ83780.1 - 3e-94 316.3 6.3 2.5e-52 178.0 0.1 3.0 1 1 2 3 3 3 3 Gamma-glutamyltranspeptidase ADH_N PF08240.7 EAQ83781.1 - 5e-29 100.2 0.2 9.5e-29 99.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ83781.1 - 6e-27 93.7 0.1 1.2e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EAQ83781.1 - 0.02 14.4 0.3 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_8 PF06259.7 EAQ83781.1 - 0.063 12.7 0.1 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase 2-Hacid_dh_C PF02826.14 EAQ83781.1 - 0.12 11.5 0.2 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2226 PF09987.4 EAQ83781.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Actin PF00022.14 EAQ83782.1 - 1.1e-86 290.7 0.0 2.4e-86 289.6 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAQ83782.1 - 0.093 11.3 0.1 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 EAQ83783.1 - 1.7e-29 102.5 1.7 3.3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EAQ83784.1 - 1.4e-70 237.7 14.9 1.8e-48 165.2 1.8 2.3 2 1 0 2 2 2 2 Transcription factor Tfb4 Reprolysin_4 PF13583.1 EAQ83784.1 - 0.016 14.7 3.2 0.028 13.9 2.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like UNC45-central PF11701.3 EAQ83785.1 - 1.5e-42 144.9 0.9 5.5e-41 139.8 0.0 3.7 5 0 0 5 5 5 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EAQ83785.1 - 0.018 15.3 18.7 55 4.1 5.2 6.2 4 2 1 5 5 5 0 HEAT repeats Arm PF00514.18 EAQ83785.1 - 0.18 11.7 11.4 40 4.2 0.1 6.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EAQ83785.1 - 4.2 7.9 20.5 5.1 7.7 0.1 6.6 8 0 0 8 8 8 0 HEAT-like repeat ERCC4 PF02732.10 EAQ83786.1 - 2.8e-25 88.7 0.1 4.2e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain CAF-1_p150 PF11600.3 EAQ83786.1 - 0.023 14.1 16.9 0.074 12.4 11.7 1.8 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 EAQ83786.1 - 7.7 6.3 9.3 14 5.4 6.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kinesin PF00225.18 EAQ83788.1 - 3.8e-94 315.1 0.1 6.4e-93 311.0 0.0 3.1 2 0 0 2 2 2 1 Kinesin motor domain Macoilin PF09726.4 EAQ83788.1 - 0.00027 19.3 3.4 0.00027 19.3 2.4 7.1 2 1 4 6 6 6 1 Transmembrane protein AMP-binding_C PF13193.1 EAQ83789.1 - 5.6e-16 59.2 0.1 8.8e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EAQ83789.1 - 0.00011 20.7 1.0 0.00016 20.1 0.7 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Reprolysin_5 PF13688.1 EAQ83790.1 - 1.1e-53 182.1 1.5 1.1e-53 182.1 1.0 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAQ83790.1 - 5.6e-48 163.2 0.1 1.2e-47 162.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAQ83790.1 - 1e-37 129.6 0.0 1.9e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAQ83790.1 - 3e-19 69.7 0.0 6.3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EAQ83790.1 - 4.8e-09 36.3 16.7 4.8e-09 36.3 11.6 4.2 2 2 1 3 3 3 1 Disintegrin Phage_sheath_1 PF04984.9 EAQ83792.1 - 0.19 10.1 3.5 0.11 10.9 0.4 1.8 2 0 0 2 2 2 0 Phage tail sheath protein Ribosomal_L3 PF00297.17 EAQ83793.1 - 5.3e-119 396.4 9.6 6.4e-119 396.1 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 EAQ83794.1 - 1.6e-56 185.7 26.8 4.8e-08 32.2 0.0 10.5 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ83794.1 - 1.7e-51 168.0 18.3 1.3e-05 24.7 0.8 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ83794.1 - 1.1e-49 165.9 42.9 1.2e-13 50.4 1.3 6.4 2 2 5 8 8 8 8 TPR repeat TPR_8 PF13181.1 EAQ83794.1 - 3.9e-42 138.8 14.2 2.5e-06 26.8 0.5 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ83794.1 - 2.1e-34 117.4 11.3 2.5e-07 31.1 0.1 6.8 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ83794.1 - 2.2e-33 111.6 11.6 0.00048 20.5 0.0 9.9 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ83794.1 - 2.5e-31 107.4 19.0 3e-06 27.0 1.2 6.8 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ83794.1 - 4.8e-31 104.3 14.1 0.00041 20.3 0.0 10.2 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ83794.1 - 6.9e-24 82.6 11.6 0.027 14.9 0.9 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ83794.1 - 3.2e-23 81.8 14.0 0.0004 20.6 0.1 6.7 4 1 2 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ83794.1 - 5.6e-23 78.8 7.9 0.0031 17.1 0.0 9.5 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ83794.1 - 2.6e-15 56.0 14.0 0.008 16.0 0.2 7.1 1 1 7 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EAQ83794.1 - 1.2e-14 54.1 11.4 1.4e-08 34.7 1.2 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EAQ83794.1 - 1.3e-12 47.4 5.8 0.00025 20.1 0.7 4.5 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 EAQ83794.1 - 5e-05 23.3 1.7 0.26 11.4 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EAQ83794.1 - 0.021 14.7 15.2 1 9.2 0.0 4.9 3 3 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EAQ83794.1 - 0.18 11.6 16.2 1.8 8.4 1.0 5.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EAQ83794.1 - 0.29 9.8 1.9 2.8 6.5 0.1 2.8 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) GAS PF13851.1 EAQ83794.1 - 0.59 9.2 3.8 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SNAP PF14938.1 EAQ83794.1 - 1.2 8.2 14.8 17 4.4 0.3 4.9 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 EAQ83794.1 - 4 7.3 17.4 13 5.6 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EAQ83794.1 - 5.5 5.6 11.9 2.5 6.7 0.0 4.0 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 DUF1751 PF08551.5 EAQ83796.1 - 4.4e-28 97.5 2.7 8.9e-28 96.5 1.9 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Defensin_big PF14862.1 EAQ83796.1 - 0.026 14.5 1.2 0.067 13.2 0.0 2.3 3 0 0 3 3 3 0 Big defensin Rhomboid PF01694.17 EAQ83796.1 - 0.18 11.7 10.0 0.2 11.6 6.1 1.6 2 0 0 2 2 2 0 Rhomboid family WD40 PF00400.27 EAQ83797.1 - 5.2e-17 61.0 5.1 5e-05 23.0 0.0 7.5 6 1 1 7 7 7 5 WD domain, G-beta repeat LisH PF08513.6 EAQ83797.1 - 7.8e-08 31.8 0.1 1.7e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 LisH Apc4_WD40 PF12894.2 EAQ83797.1 - 0.00015 21.1 1.2 0.059 12.8 0.0 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EAQ83797.1 - 0.051 13.2 0.0 2.9 7.5 0.0 3.0 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DNA_pol3_a_NII PF11490.3 EAQ83797.1 - 0.18 11.4 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II MFS_1 PF07690.11 EAQ83798.1 - 1.6e-36 125.7 43.4 1.6e-36 125.7 30.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ83798.1 - 2.5e-13 49.4 14.2 2.5e-13 49.4 9.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.6 EAQ83798.1 - 7.3 6.3 6.4 0.46 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.19 EAQ83799.1 - 3.9e-39 134.4 11.7 4.3e-39 134.3 8.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83799.1 - 0.00039 19.2 25.8 0.00094 17.9 17.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 EAQ83800.1 - 7.1e-28 97.6 3.4 1.4e-27 96.6 2.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ83800.1 - 3.9e-13 49.7 0.3 6.2e-13 49.0 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ83800.1 - 2.7e-11 43.4 5.2 7.5e-10 38.7 3.4 2.7 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EAQ83800.1 - 0.017 15.1 0.7 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding DUF1776 PF08643.5 EAQ83800.1 - 0.05 12.7 0.1 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pkinase PF00069.20 EAQ83801.1 - 7.1e-08 31.9 0.0 1.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83801.1 - 0.037 13.0 0.0 0.14 11.2 0.0 1.9 2 1 0 2 2 2 0 Protein tyrosine kinase Sof1 PF04158.9 EAQ83803.1 - 3.7e-32 110.1 11.1 6.7e-32 109.3 7.7 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EAQ83803.1 - 3.8e-32 108.9 11.4 8.7e-09 34.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EAQ83803.1 - 9.5e-05 22.1 0.1 1.6 8.5 0.0 4.2 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EAQ83803.1 - 0.0041 17.3 0.2 3 8.2 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain DUF3022 PF11226.3 EAQ83803.1 - 0.01 15.7 0.3 0.019 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Cytochrom_D1 PF02239.11 EAQ83803.1 - 0.034 12.4 0.0 0.063 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain PCI PF01399.22 EAQ83804.1 - 5.5e-19 68.4 1.0 1.7e-18 66.8 0.1 2.3 3 1 0 3 3 3 1 PCI domain TPR_7 PF13176.1 EAQ83804.1 - 3.6e-08 32.6 1.4 0.15 11.9 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ83804.1 - 4.3e-06 26.1 4.8 0.46 10.3 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DDRGK PF09756.4 EAQ83804.1 - 0.00021 20.7 0.2 0.00048 19.5 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_16 PF13432.1 EAQ83804.1 - 0.002 18.7 11.3 3.3 8.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ83804.1 - 0.017 14.6 5.8 3.1 7.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ83804.1 - 0.018 14.9 16.2 0.99 9.3 0.2 5.4 3 1 2 6 6 6 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EAQ83804.1 - 0.039 13.7 0.5 0.093 12.4 0.4 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 EAQ83804.1 - 0.14 12.1 1.7 0.7 9.9 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF87 PF01935.12 EAQ83804.1 - 0.19 11.5 2.0 0.54 10.0 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF87 TPR_2 PF07719.12 EAQ83804.1 - 0.97 9.5 11.1 22 5.2 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ83804.1 - 6.2 7.5 7.2 71 4.1 0.0 5.4 5 2 0 5 5 5 0 Tetratricopeptide repeat Sds3 PF08598.6 EAQ83807.1 - 1.6e-53 181.2 1.5 1.9e-53 181.0 1.1 1.3 1 0 0 1 1 1 1 Sds3-like Amidinotransf PF02274.12 EAQ83807.1 - 0.028 13.4 0.1 0.058 12.4 0.0 1.5 2 0 0 2 2 2 0 Amidinotransferase LSM PF01423.17 EAQ83808.1 - 1.8e-13 49.8 0.1 3.7e-13 48.8 0.0 1.5 2 0 0 2 2 2 1 LSM domain Mob1_phocein PF03637.12 EAQ83810.1 - 2e-69 232.7 0.0 2.5e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EAQ83811.1 - 8.5e-41 139.6 0.7 1e-40 139.3 0.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.11 EAQ83812.1 - 8.8e-09 33.7 2.7 2.9e-06 25.4 0.1 3.2 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase PP2C PF00481.16 EAQ83813.1 - 4.2e-43 147.5 0.0 7.3e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAQ83813.1 - 0.00093 18.6 0.1 0.0037 16.7 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EAQ83813.1 - 0.002 17.8 0.0 0.12 12.1 0.0 2.7 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Agouti PF05039.7 EAQ83814.1 - 0.0059 16.9 0.4 0.0059 16.9 0.3 1.1 1 0 0 1 1 1 1 Agouti protein UPF0506 PF11703.3 EAQ83814.1 - 0.052 13.5 1.1 0.066 13.1 0.8 1.1 1 0 0 1 1 1 0 UPF0506 Conotoxin PF02950.12 EAQ83814.1 - 0.076 13.8 1.0 0.076 13.8 0.7 1.3 2 0 0 2 2 2 0 Conotoxin Molybdopterin PF00384.17 EAQ83816.1 - 2.3e-75 254.0 0.0 1.2e-73 248.2 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EAQ83816.1 - 3.1e-19 68.5 0.2 9.6e-19 66.9 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EAQ83816.1 - 4.6e-19 67.3 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EAQ83816.1 - 1.2e-14 54.1 0.0 3.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EAQ83816.1 - 7.1e-09 35.3 0.5 7.1e-09 35.3 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EAQ83816.1 - 0.00038 20.2 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Takusan PF04822.8 EAQ83817.1 - 0.29 10.8 1.2 0.52 10.0 0.8 1.3 1 0 0 1 1 1 0 Takusan ACBP PF00887.14 EAQ83818.1 - 2.6e-31 107.1 0.0 4.7e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein PRT_C PF08372.5 EAQ83818.1 - 0.057 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF3292 PF11696.3 EAQ83818.1 - 0.069 11.0 0.2 0.12 10.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Atg14 PF10186.4 EAQ83818.1 - 0.32 9.8 1.2 2 7.2 0.5 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribonuclease_3 PF00636.21 EAQ83819.1 - 2e-14 54.0 0.0 4.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EAQ83819.1 - 1.8e-12 47.3 0.0 3.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like WD40 PF00400.27 EAQ83820.1 - 2.6e-16 58.8 0.0 4.2e-11 42.2 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 EAQ83820.1 - 0.02 14.5 0.1 0.051 13.2 0.1 1.7 1 1 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 EAQ83820.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain TPR_10 PF13374.1 EAQ83821.1 - 3.2e-40 134.9 0.0 7.8e-11 41.5 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ83821.1 - 9.6e-27 92.7 0.0 2.1e-15 56.3 0.0 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ83821.1 - 2.1e-12 45.8 0.7 0.0012 18.5 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ83821.1 - 5.9e-12 45.0 0.0 1.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EAQ83821.1 - 4.8e-08 32.3 0.5 0.57 10.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ83821.1 - 1.2e-06 28.6 1.1 16 6.4 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ83821.1 - 4.6e-06 26.1 0.2 0.068 12.8 0.0 3.4 1 1 2 3 3 3 3 TPR repeat TPR_4 PF07721.9 EAQ83821.1 - 5.4e-06 26.3 0.1 6.5 7.5 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ83821.1 - 9.5e-06 25.4 0.1 0.25 11.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ83821.1 - 1.2e-05 24.6 0.0 0.5 10.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ83821.1 - 0.00011 22.7 0.1 0.62 10.8 0.0 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat NACHT PF05729.7 EAQ83821.1 - 0.00018 21.1 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.1 EAQ83821.1 - 0.00043 20.5 0.2 2.7 8.4 0.1 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ83821.1 - 0.00087 18.9 0.1 2.5 8.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ83821.1 - 0.0056 16.7 0.0 1.1 9.4 0.0 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_25 PF13481.1 EAQ83821.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ83821.1 - 0.013 15.6 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ83821.1 - 0.022 15.5 0.0 0.062 14.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain TPR_6 PF13174.1 EAQ83821.1 - 0.034 14.6 2.2 18 6.0 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.15 EAQ83821.1 - 0.053 13.5 0.8 33 4.7 0.1 3.8 4 0 0 4 4 3 0 PPR repeat MRP-S33 PF08293.6 EAQ83822.1 - 4.2e-18 65.1 0.0 6.4e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 EAQ83823.1 - 1.1e-37 125.4 0.4 2.8e-06 26.4 0.0 9.4 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat ATG16 PF08614.6 EAQ83823.1 - 0.15 11.9 2.2 0.25 11.1 1.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0061 PF02696.9 EAQ83824.1 - 1.6e-116 389.5 0.0 4.1e-110 368.3 0.0 1.9 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family SHMT PF00464.14 EAQ83824.1 - 0.3 9.4 0.0 0.44 8.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Aldo_ket_red PF00248.16 EAQ83825.1 - 2.4e-43 147.9 0.0 3.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.7 EAQ83826.1 - 1.2e-05 24.3 5.0 1.2e-05 24.3 3.4 2.1 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 LUC7 PF03194.10 EAQ83826.1 - 0.0062 16.0 2.4 0.011 15.3 1.6 1.4 1 0 0 1 1 1 1 LUC7 N_terminus DUF3585 PF12130.3 EAQ83826.1 - 0.0071 16.1 7.3 0.014 15.2 5.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3585) DUF3573 PF12097.3 EAQ83826.1 - 0.074 11.6 0.3 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ERM PF00769.14 EAQ83826.1 - 0.28 10.6 12.8 0.54 9.7 8.9 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EAQ83826.1 - 1 7.1 2.7 1.7 6.3 1.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Blt1 PF12754.2 EAQ83828.1 - 6.6e-45 154.0 0.0 7.9e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 EAQ83828.1 - 0.0002 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Mucin PF01456.12 EAQ83828.1 - 0.89 9.3 12.2 1.7 8.4 8.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EAQ83828.1 - 8.5 4.2 8.4 11 3.8 5.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cofilin_ADF PF00241.15 EAQ83829.1 - 8.2e-35 119.4 1.5 9.8e-35 119.2 1.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.19 EAQ83830.1 - 1.9e-113 379.7 9.2 2.1e-113 379.5 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IER PF05760.7 EAQ83832.1 - 0.24 11.3 6.9 0.11 12.4 2.9 1.6 1 1 0 1 1 1 0 Immediate early response protein (IER) MRI PF15325.1 EAQ83832.1 - 4.1 8.4 10.2 19 6.2 0.1 2.6 2 1 0 2 2 2 0 Modulator of retrovirus infection Inhibitor_I53 PF11714.3 EAQ83833.1 - 0.16 11.9 4.1 0.49 10.4 2.8 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin PIH1 PF08190.7 EAQ83833.1 - 0.22 10.9 2.2 0.29 10.5 1.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RAP1 PF07218.6 EAQ83833.1 - 0.91 7.5 10.7 1.2 7.1 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pneumo_att_G PF05539.6 EAQ83833.1 - 5 6.3 10.1 6.2 6.0 7.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4479 PF14794.1 EAQ83835.1 - 0.0032 16.9 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4479) Cas_Csa4 PF09703.5 EAQ83835.1 - 0.0072 15.3 0.0 0.008 15.1 0.0 1.0 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csa4) RR_TM4-6 PF06459.7 EAQ83838.1 - 0.12 12.2 0.4 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Baculo_PEP_C PF04513.7 EAQ83840.1 - 5.6e-07 29.4 10.9 0.12 12.1 0.1 5.3 2 1 4 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EAQ83840.1 - 9.6e-05 21.7 17.4 0.015 14.4 0.0 4.5 1 1 3 5 5 5 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 EAQ83840.1 - 0.0018 16.8 33.0 0.01 14.3 14.4 3.2 1 1 3 4 4 4 4 AAA domain DUF1664 PF07889.7 EAQ83840.1 - 0.0064 16.2 30.3 0.96 9.2 1.1 6.7 2 2 5 7 7 7 1 Protein of unknown function (DUF1664) AIP3 PF03915.8 EAQ83840.1 - 0.017 14.0 35.8 0.15 10.9 1.9 3.2 1 1 1 2 2 2 0 Actin interacting protein 3 LPP PF04728.8 EAQ83840.1 - 0.065 13.0 0.4 0.065 13.0 0.3 5.0 7 0 0 7 7 6 0 Lipoprotein leucine-zipper DUF3829 PF12889.2 EAQ83840.1 - 0.26 10.4 27.9 0.01 15.0 14.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3829) Phage_GP20 PF06810.6 EAQ83840.1 - 1.2 8.5 39.6 0.025 14.0 2.9 5.3 2 2 4 6 6 6 0 Phage minor structural protein GP20 Bacillus_HBL PF05791.6 EAQ83840.1 - 1.2 8.4 31.2 0.065 12.6 1.1 4.8 3 3 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EAQ83840.1 - 2 6.7 24.2 2.4 6.4 11.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF2605 PF10792.4 EAQ83840.1 - 4.2 7.0 12.1 0.29 10.8 1.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) ERM PF00769.14 EAQ83840.1 - 6.5 6.2 46.8 0.25 10.8 2.7 3.0 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Fib_alpha PF08702.5 EAQ83840.1 - 8.3 6.5 26.1 5.1 7.2 5.2 4.9 1 1 3 6 6 6 0 Fibrinogen alpha/beta chain family HTH_Tnp_Tc3_2 PF01498.13 EAQ83841.1 - 1.9e-20 72.6 1.9 1.9e-20 72.6 1.3 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EAQ83841.1 - 1.6e-17 63.6 0.4 3e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EAQ83841.1 - 7.3e-10 38.9 2.0 1.5e-09 37.9 1.4 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EAQ83841.1 - 0.00046 19.7 0.2 0.00046 19.7 0.1 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.1 EAQ83841.1 - 0.0006 19.7 3.8 0.0023 17.9 0.0 2.9 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.1 EAQ83841.1 - 0.0031 18.2 1.5 0.0031 18.2 1.0 2.1 2 1 0 2 2 1 1 Homeodomain-like domain HTH_7 PF02796.10 EAQ83841.1 - 0.014 15.2 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.8 EAQ83841.1 - 0.035 13.5 0.2 1.6 8.2 0.0 3.2 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain rve PF00665.21 EAQ83841.1 - 0.045 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HTH_38 PF13936.1 EAQ83841.1 - 0.11 12.0 1.6 0.91 9.1 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EAQ83841.1 - 0.21 10.8 5.2 7.3 5.8 0.1 4.0 3 1 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EAQ83841.1 - 0.73 9.8 4.9 0.9 9.6 0.7 2.5 2 0 0 2 2 2 0 HTH-like domain TIP49 PF06068.8 EAQ83842.1 - 2.4e-175 583.0 3.1 2.9e-175 582.7 2.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EAQ83842.1 - 1.2e-08 35.2 0.3 2.2e-05 24.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAQ83842.1 - 6e-08 32.0 0.5 3.7e-05 22.9 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EAQ83842.1 - 1.5e-06 27.3 0.5 2.5e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EAQ83842.1 - 5.1e-05 23.3 0.1 0.0062 16.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAQ83842.1 - 0.00025 21.2 0.1 0.55 10.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EAQ83842.1 - 0.0011 18.1 0.6 0.017 14.2 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EAQ83842.1 - 0.0019 18.0 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAQ83842.1 - 0.01 15.2 0.1 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EAQ83842.1 - 0.01 15.2 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EAQ83842.1 - 0.015 15.0 0.2 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAQ83842.1 - 0.026 14.2 0.8 0.081 12.6 0.2 2.1 1 1 1 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EAQ83842.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EAQ83842.1 - 0.066 12.7 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EAQ83842.1 - 0.086 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GYF PF02213.11 EAQ83843.1 - 8.4e-10 38.0 0.1 1.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.1 EAQ83843.1 - 3.6 7.7 7.9 1e+02 3.0 5.5 2.6 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 UFD1 PF03152.9 EAQ83844.1 - 1.2e-60 203.6 0.0 1.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 VEFS-Box PF09733.4 EAQ83846.1 - 3.6e-08 33.1 0.1 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 EAQ83846.1 - 0.00025 20.6 9.7 0.00025 20.6 6.7 1.9 2 0 0 2 2 2 1 PHD-finger DUF382 PF04037.8 EAQ83847.1 - 1.8e-62 208.8 0.8 1.8e-62 208.8 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EAQ83847.1 - 7.2e-22 76.5 2.9 1.6e-21 75.3 2.0 1.7 1 0 0 1 1 1 1 PSP TPT PF03151.11 EAQ83848.1 - 4.7e-38 130.2 0.5 4.7e-38 130.2 0.3 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EAQ83848.1 - 2.3e-10 39.8 5.3 3.7e-09 35.9 3.6 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EAQ83848.1 - 3.2e-06 27.1 25.8 0.00031 20.7 5.9 3.1 3 2 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EAQ83848.1 - 0.032 13.0 0.4 0.31 9.8 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Multi_Drug_Res PF00893.14 EAQ83848.1 - 6.4 7.3 10.0 1.5 9.3 0.9 3.2 4 0 0 4 4 4 0 Small Multidrug Resistance protein ORC5_C PF14630.1 EAQ83849.1 - 5.7e-26 91.5 0.1 8.1e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EAQ83849.1 - 7e-15 55.4 0.1 2.2e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EAQ83849.1 - 0.0082 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAQ83849.1 - 0.0098 15.8 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ83849.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ83849.1 - 0.027 15.2 0.0 0.043 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ83849.1 - 0.028 13.2 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EAQ83849.1 - 0.04 14.2 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAQ83849.1 - 0.056 12.3 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EAQ83849.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EAQ83849.1 - 0.14 11.5 0.1 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RecA PF00154.16 EAQ83849.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein TrwB_AAD_bind PF10412.4 EAQ83849.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zn_clus PF00172.13 EAQ83850.1 - 9.3e-08 31.8 6.9 1.5e-07 31.2 4.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ83850.1 - 4.5e-06 25.5 0.0 6.5e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_ab PF00006.20 EAQ83851.1 - 9.6e-62 208.2 0.0 1.4e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAQ83851.1 - 6.1e-25 87.8 0.5 1.2e-24 86.9 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EAQ83851.1 - 3.7e-23 81.5 0.5 1.4e-22 79.6 0.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Arch_ATPase PF01637.13 EAQ83851.1 - 0.0071 16.0 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_25 PF13481.1 EAQ83851.1 - 0.013 14.9 0.6 0.058 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EAQ83851.1 - 0.015 14.4 0.1 0.029 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EAQ83851.1 - 0.016 15.3 0.1 0.62 10.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EAQ83851.1 - 0.018 14.7 0.1 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EAQ83851.1 - 0.024 13.7 0.1 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EAQ83851.1 - 0.024 14.2 0.1 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EAQ83851.1 - 0.031 14.2 0.4 0.24 11.3 0.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EAQ83851.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EAQ83851.1 - 0.077 13.1 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ83851.1 - 0.083 11.7 0.7 0.63 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EAQ83852.1 - 1.3e-24 86.1 0.0 2.7e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain AAA_2 PF07724.9 EAQ83854.1 - 8.5e-34 116.9 0.0 3.7e-33 114.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EAQ83854.1 - 3.4e-13 49.9 0.0 8e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EAQ83854.1 - 1.3e-10 41.0 0.0 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EAQ83854.1 - 7.3e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAQ83854.1 - 5.4e-05 23.3 0.5 0.00099 19.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAQ83854.1 - 0.00012 22.0 0.6 0.0003 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAQ83854.1 - 0.00014 22.6 0.0 0.00041 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 EAQ83854.1 - 0.00034 19.5 0.0 0.00068 18.5 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 EAQ83854.1 - 0.001 19.1 0.1 0.056 13.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EAQ83854.1 - 0.0016 17.8 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EAQ83854.1 - 0.021 15.1 0.6 0.06 13.6 0.1 2.1 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EAQ83854.1 - 0.03 13.4 0.0 0.88 8.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SOUL PF04832.7 EAQ83854.1 - 0.039 13.4 0.1 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein T2SE PF00437.15 EAQ83854.1 - 0.051 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EAQ83854.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EAQ83854.1 - 0.065 13.5 0.5 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 EAQ83854.1 - 0.072 12.5 0.0 0.75 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 EAQ83854.1 - 0.09 12.6 1.0 0.33 10.7 0.0 2.3 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EAQ83854.1 - 0.098 12.9 1.1 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain RPT PF13446.1 EAQ83854.1 - 0.15 11.4 0.1 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein WD40 PF00400.27 EAQ83855.1 - 7.9e-36 120.6 12.0 1.4e-11 43.8 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EAQ83855.1 - 0.0023 17.4 0.0 49 3.5 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EAQ83855.1 - 0.3 9.8 0.2 4.9 5.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Transket_pyr PF02779.19 EAQ83856.1 - 9.7e-64 214.1 0.0 2.1e-63 213.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EAQ83856.1 - 4.9e-58 196.2 0.0 6.8e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TFIIH_BTF_p62_N PF08567.6 EAQ83857.1 - 1.6e-26 91.7 0.0 3.8e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 EAQ83857.1 - 7.2e-24 83.3 4.1 6.3e-13 48.2 0.3 3.1 3 1 0 3 3 3 2 BSD domain Tup_N PF08581.5 EAQ83857.1 - 0.075 13.2 2.9 0.13 12.4 0.8 2.2 2 0 0 2 2 2 0 Tup N-terminal TerB-C PF15615.1 EAQ83857.1 - 9.9 6.4 9.7 1.3 9.2 0.1 3.5 3 1 1 4 4 4 0 TerB-C domain AAA PF00004.24 EAQ83858.1 - 4e-37 127.3 0.0 1.9e-36 125.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ83858.1 - 1.3e-06 28.5 0.2 1.2e-05 25.3 0.2 2.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EAQ83858.1 - 7.3e-05 21.9 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAQ83858.1 - 8.4e-05 22.7 0.1 0.0048 17.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ83858.1 - 0.00027 21.7 0.0 0.0012 19.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ83858.1 - 0.00054 19.8 0.1 0.0033 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAQ83858.1 - 0.0011 18.8 0.0 0.0048 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAQ83858.1 - 0.0043 16.4 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EAQ83858.1 - 0.0091 15.7 0.0 0.033 13.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAQ83858.1 - 0.014 15.1 0.1 0.014 15.1 0.0 3.2 4 0 0 4 4 4 0 Part of AAA domain Mg_chelatase PF01078.16 EAQ83858.1 - 0.023 13.8 0.0 0.06 12.4 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EAQ83858.1 - 0.024 13.3 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EAQ83858.1 - 0.032 14.3 0.0 0.096 12.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.1 EAQ83858.1 - 0.033 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ83858.1 - 0.042 13.8 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 EAQ83858.1 - 0.064 12.7 0.1 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EAQ83858.1 - 0.082 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain RVT_2 PF07727.9 EAQ83859.1 - 8.8e-38 129.6 0.0 1.6e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ83859.1 - 8.3e-15 54.9 0.0 2.5e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ83859.1 - 0.0013 18.3 0.0 0.0045 16.6 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain DZR PF12773.2 EAQ83859.1 - 3.7 7.4 10.8 2.8 7.8 3.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon Mus7 PF09462.5 EAQ83860.1 - 1.7e-197 658.0 0.1 2.6e-197 657.4 0.1 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family COX4 PF02936.9 EAQ83861.1 - 2.8e-51 173.0 0.1 3.2e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 EAQ83861.1 - 0.0026 17.8 0.2 0.0073 16.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1104) DAO PF01266.19 EAQ83863.1 - 1.3e-28 99.9 0.0 2.3e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase RGS PF00615.14 EAQ83864.1 - 3.4e-10 40.0 0.0 5.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_C48 PF02902.14 EAQ83867.1 - 7.5e-15 55.1 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain U79_P34 PF03064.11 EAQ83867.1 - 0.11 12.0 9.7 0.21 11.0 6.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.4 EAQ83867.1 - 9.8 5.5 22.1 21 4.4 15.3 1.5 1 0 0 1 1 1 0 DDRGK domain Cupin_8 PF13621.1 EAQ83869.1 - 1e-16 61.2 0.0 5.7e-09 35.8 0.0 2.3 1 1 1 2 2 2 2 Cupin-like domain Kelch_4 PF13418.1 EAQ83869.1 - 2.7e-13 49.4 13.9 2.8e-10 39.8 0.3 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain LCM PF04072.9 EAQ83869.1 - 3.5e-11 42.9 0.0 5.6e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 Leucine carboxyl methyltransferase Kelch_6 PF13964.1 EAQ83869.1 - 4.6e-06 26.5 1.6 0.0052 16.9 0.0 3.6 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EAQ83869.1 - 0.00015 21.8 0.2 0.00015 21.8 0.1 3.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Cupin_4 PF08007.7 EAQ83869.1 - 0.00029 20.1 0.2 0.00061 19.1 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.1 EAQ83869.1 - 0.12 12.3 0.7 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 EAQ83869.1 - 0.13 11.8 0.1 5.7 6.5 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 EAQ83869.1 - 0.34 10.7 6.2 11 5.9 0.5 3.5 4 0 0 4 4 4 0 Kelch motif Mito_carr PF00153.22 EAQ83870.1 - 4.7e-40 135.2 11.8 3e-16 58.8 0.1 3.4 2 1 2 4 4 4 3 Mitochondrial carrier protein MFS_1 PF07690.11 EAQ83871.1 - 7e-24 84.1 62.9 2.8e-18 65.7 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EAQ83872.1 - 3.9e-14 52.1 28.9 3.9e-14 52.1 20.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EAQ83872.1 - 1.9e-05 24.0 7.6 0.00014 21.1 2.6 3.0 2 1 0 2 2 2 1 Nodulin-like His_Phos_2 PF00328.17 EAQ83873.1 - 1.6e-06 27.7 0.1 1.6e-06 27.7 0.1 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) stn_TNFRSF12A PF12191.3 EAQ83873.1 - 0.084 12.9 0.4 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SKG6 PF08693.5 EAQ83874.1 - 0.00017 20.8 0.2 0.0004 19.6 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4229 PF14012.1 EAQ83874.1 - 0.0049 16.7 0.4 0.0093 15.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) VPEP PF07589.6 EAQ83874.1 - 0.15 11.9 3.0 0.45 10.4 2.1 1.8 1 0 0 1 1 1 0 PEP-CTERM motif LSM PF01423.17 EAQ83875.1 - 2.3e-20 71.9 0.2 2.7e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain PRMT5 PF05185.11 EAQ83876.1 - 7.4e-168 559.1 0.0 9.4e-168 558.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EAQ83877.1 - 1.6e-26 92.3 0.1 6.8e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAQ83877.1 - 4.5e-22 78.0 0.0 9.8e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAQ83877.1 - 7.8e-11 41.6 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAQ83877.1 - 2e-08 34.4 0.1 5.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EAQ83877.1 - 9.5e-08 31.7 0.4 3.7e-07 29.7 0.2 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase SRP54 PF00448.17 EAQ83877.1 - 0.00021 20.8 0.1 0.00066 19.1 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EAQ83877.1 - 0.0022 17.8 0.0 0.65 9.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EAQ83877.1 - 0.0049 15.8 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 EAQ83877.1 - 0.017 15.3 0.6 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EAQ83877.1 - 0.032 13.0 0.0 0.09 11.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Response_reg PF00072.19 EAQ83877.1 - 0.048 13.6 1.0 0.17 11.9 0.1 2.3 3 0 0 3 3 3 0 Response regulator receiver domain PhoH PF02562.11 EAQ83877.1 - 0.085 12.0 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 EAQ83877.1 - 0.091 12.7 0.0 0.39 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EAQ83877.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EAQ83877.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2435 PF10363.4 EAQ83880.1 - 5.5e-18 64.6 0.1 1.4e-16 60.1 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EAQ83880.1 - 2.7e-14 52.2 0.6 7.4e-14 50.8 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) BLYB PF05289.6 EAQ83880.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Nramp PF01566.13 EAQ83882.1 - 1e-69 235.0 12.4 1.8e-69 234.2 8.6 1.3 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DDHD PF02862.12 EAQ83883.1 - 7.3e-35 120.8 0.1 2e-17 63.7 0.0 3.1 2 1 1 3 3 3 2 DDHD domain Na_Ca_ex PF01699.19 EAQ83883.1 - 5.1e-21 74.7 28.6 6.2e-11 42.0 6.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Abhydrolase_5 PF12695.2 EAQ83883.1 - 0.0047 16.6 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family YfhO PF09586.5 EAQ83883.1 - 0.054 11.5 0.0 0.076 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CDC45 PF02724.9 EAQ83883.1 - 0.14 10.2 2.6 0.2 9.6 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EAQ83883.1 - 0.22 10.9 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein FSA_C PF10479.4 EAQ83883.1 - 0.73 7.8 0.3 1.2 7.1 0.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1227 PF06777.6 EAQ83884.1 - 3.5e-62 208.4 0.2 7.9e-62 207.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EAQ83884.1 - 1.3e-43 148.8 0.0 3.8e-43 147.3 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EAQ83884.1 - 1.5e-33 115.6 7.9 4.9e-17 61.8 2.9 2.4 1 1 1 2 2 2 2 DEAD_2 ResIII PF04851.10 EAQ83884.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAQ83884.1 - 0.00045 19.1 0.2 0.0018 17.1 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 EAQ83884.1 - 0.00077 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EAQ83884.1 - 0.0009 18.7 0.1 0.0056 16.1 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EAQ83884.1 - 0.016 14.9 0.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain zf-C2H2 PF00096.21 EAQ83888.1 - 5.7e-14 51.5 19.4 4.9e-05 23.4 0.6 3.8 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ83888.1 - 7.5e-11 41.5 16.4 0.003 17.7 0.4 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ83888.1 - 9.9e-05 22.4 22.8 0.005 17.0 1.8 4.4 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EAQ83888.1 - 0.38 10.9 11.6 5.4 7.2 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EAQ83888.1 - 0.79 10.1 12.5 2 8.8 5.5 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger zf-BED PF02892.10 EAQ83888.1 - 1 9.1 8.1 17 5.2 2.5 3.1 2 1 1 3 3 3 0 BED zinc finger zf-met PF12874.2 EAQ83888.1 - 3.6 7.9 8.0 10 6.4 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EAQ83888.1 - 9.4 6.6 10.2 5.1 7.5 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PRP3 PF08572.5 EAQ83889.1 - 3.7e-70 235.7 7.1 5.2e-70 235.2 4.9 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EAQ83889.1 - 3.6e-38 130.1 0.1 7.1e-38 129.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EAQ83890.1 - 1.2e-86 290.4 0.1 2.2e-86 289.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EAQ83890.1 - 9.1e-62 207.8 0.1 2.3e-61 206.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EAQ83890.1 - 1.1e-28 100.5 1.3 1.3e-26 93.7 0.5 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EAQ83890.1 - 1.2e-21 77.1 0.0 2.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EAQ83890.1 - 4.5e-18 64.9 0.0 1.8e-17 63.0 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DSBA PF01323.15 EAQ83891.1 - 3.5e-11 43.0 0.0 4.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Histone PF00125.19 EAQ83892.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAQ83892.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAQ83892.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EAQ83892.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EAQ83894.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAQ83894.1 - 6.6e-05 23.0 0.1 8.3e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EAQ83894.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EAQ83894.1 - 0.00034 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EAQ83894.1 - 0.021 14.5 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EAQ83894.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EAQ83894.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sugar_tr PF00083.19 EAQ83897.1 - 2.1e-134 448.4 18.3 2.4e-134 448.2 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83897.1 - 2.4e-19 69.2 34.7 6.2e-16 58.0 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ83897.1 - 0.059 13.1 0.0 0.059 13.1 0.0 4.3 4 1 1 5 5 5 0 MFS_1 like family AA_permease PF00324.16 EAQ83898.1 - 2.1e-100 336.3 42.2 6e-51 173.2 4.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAQ83898.1 - 1.1e-24 86.8 48.6 3.9e-14 52.0 21.8 2.0 1 1 1 2 2 2 2 Amino acid permease DDE_1 PF03184.14 EAQ83899.1 - 8.2e-47 159.1 0.0 1.4e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EAQ83899.1 - 0.0051 16.1 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EPSP_synthase PF00275.15 EAQ83900.1 - 1.4e-126 422.3 0.0 2.3e-126 421.6 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHquinase_I PF01487.10 EAQ83900.1 - 7.1e-52 176.2 0.0 8.4e-50 169.5 0.0 2.5 1 1 0 1 1 1 1 Type I 3-dehydroquinase DHQ_synthase PF01761.15 EAQ83900.1 - 7.7e-52 175.7 0.0 9.9e-33 113.1 0.0 2.4 1 1 1 2 2 2 2 3-dehydroquinate synthase SKI PF01202.17 EAQ83900.1 - 3.4e-35 121.2 0.0 2.4e-33 115.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EAQ83900.1 - 1.1e-24 86.3 0.0 2.5e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EAQ83900.1 - 6.1e-08 32.8 0.0 2.5e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EAQ83900.1 - 0.00054 20.7 0.0 0.0014 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 EAQ83901.1 - 1.2e-08 34.8 16.5 0.0058 16.9 1.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ83901.1 - 1.1e-05 25.4 17.6 0.0038 17.4 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger RasGAP PF00616.14 EAQ83903.1 - 1.6e-47 161.7 0.0 3.1e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EAQ83903.1 - 9.3e-09 35.3 0.1 2.2e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_N PF03159.13 EAQ83904.1 - 1.4e-106 355.1 0.0 2.1e-106 354.6 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Uso1_p115_head PF04869.9 EAQ83905.1 - 7.9e-115 382.8 0.0 1.3e-114 382.1 0.0 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EAQ83905.1 - 1.4e-11 44.5 25.2 1.4e-11 44.5 17.5 3.5 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region IncA PF04156.9 EAQ83905.1 - 0.0096 15.5 35.9 0.25 10.9 10.4 3.5 1 1 2 3 3 3 2 IncA protein Fib_alpha PF08702.5 EAQ83905.1 - 2.6 8.1 20.1 3 7.9 1.5 3.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Dicty_REP PF05086.7 EAQ83905.1 - 5.7 4.5 12.8 10 3.7 8.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ATG16 PF08614.6 EAQ83905.1 - 5.8 6.6 42.3 0.87 9.3 5.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Methyltransf_18 PF12847.2 EAQ83906.1 - 5.9e-11 42.9 0.0 2e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ83906.1 - 1.1e-10 41.8 0.0 3.6e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAQ83906.1 - 2.6e-10 39.9 0.0 4.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EAQ83906.1 - 3.2e-10 39.7 0.0 6.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ83906.1 - 5.7e-09 36.0 0.1 1.4e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ83906.1 - 2.7e-07 30.9 0.0 6.2e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ83906.1 - 4.2e-07 29.8 0.0 1.3e-06 28.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAQ83906.1 - 1.6e-06 27.6 0.1 2.8e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EAQ83906.1 - 0.00012 21.2 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EAQ83906.1 - 0.00027 21.3 0.1 0.0012 19.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ83906.1 - 0.0048 16.0 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EAQ83906.1 - 0.0054 16.2 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EAQ83906.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PRMT5 PF05185.11 EAQ83906.1 - 0.0061 15.5 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.1 EAQ83906.1 - 0.012 16.4 0.0 0.078 13.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EAQ83906.1 - 0.017 13.8 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Met_10 PF02475.11 EAQ83906.1 - 0.023 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.14 EAQ83906.1 - 0.024 14.6 0.1 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.9 EAQ83906.1 - 0.045 12.9 0.2 0.12 11.5 0.2 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 EAQ83906.1 - 0.07 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF1202 PF06717.6 EAQ83906.1 - 0.078 12.2 0.4 0.13 11.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) CRA PF06589.6 EAQ83906.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) OPT PF03169.10 EAQ83907.1 - 1.5e-140 469.5 18.4 1.8e-140 469.3 12.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EAQ83907.1 - 2.8 7.9 14.1 0.12 12.3 0.4 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) Rav1p_C PF12234.3 EAQ83908.1 - 3.2e-261 868.0 0.0 1.8e-260 865.5 0.0 1.9 1 1 0 1 1 1 1 RAVE protein 1 C terminal DUF3712 PF12505.3 EAQ83908.1 - 2.1e-09 37.4 0.5 1e-07 31.9 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EAQ83908.1 - 0.0013 19.0 1.3 2.2 8.7 0.0 4.1 3 0 0 3 3 3 1 Late embryogenesis abundant protein DUF872 PF05915.7 EAQ83908.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Rax2 PF12768.2 EAQ83908.1 - 0.34 10.0 0.0 0.7 9.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity OTCace PF00185.19 EAQ83909.1 - 3e-40 137.6 0.0 4.4e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EAQ83909.1 - 5.7e-40 136.2 0.2 8.6e-40 135.6 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ALS_ss_C PF10369.4 EAQ83910.1 - 1.5e-19 69.4 0.0 3.2e-18 65.2 0.0 2.6 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EAQ83910.1 - 1.3e-12 46.9 0.1 2.3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EAQ83910.1 - 6.5e-09 35.4 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF974 PF06159.8 EAQ83911.1 - 7.5e-91 304.0 0.0 9.8e-91 303.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.24 EAQ83911.1 - 4.3e-09 35.8 0.1 7.8e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EAQ83911.1 - 5.9e-06 25.8 0.5 0.00082 18.9 0.0 2.8 2 0 0 2 2 2 2 KH domain DENN PF02141.16 EAQ83912.1 - 1e-56 191.5 0.0 2e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EAQ83912.1 - 2.1e-18 66.1 0.2 3.8e-18 65.3 0.2 1.4 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EAQ83912.1 - 4.1e-17 61.8 0.0 8.3e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 EAQ83912.1 - 0.011 15.4 7.7 0.02 14.6 5.3 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3038 PF11237.3 EAQ83912.1 - 0.13 12.0 0.1 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) PHD PF00628.24 EAQ83912.1 - 0.16 11.6 6.8 0.4 10.4 4.7 1.7 1 0 0 1 1 1 0 PHD-finger SPA PF08616.5 EAQ83912.1 - 0.23 11.1 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis C1_2 PF03107.11 EAQ83912.1 - 3.3 7.9 7.1 7.8 6.7 4.9 1.6 1 0 0 1 1 1 0 C1 domain C1_3 PF07649.7 EAQ83912.1 - 3.7 7.6 6.2 7.3 6.7 4.3 1.5 1 0 0 1 1 1 0 C1-like domain PPI_Ypi1 PF07491.6 EAQ83913.1 - 8.4e-23 79.7 5.0 4e-22 77.6 3.5 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor Cwf_Cwc_15 PF04889.7 EAQ83913.1 - 0.069 12.8 2.5 0.12 12.0 1.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EAQ83913.1 - 0.25 9.3 6.5 0.33 8.9 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.6 EAQ83913.1 - 8.3 4.3 6.3 9.2 4.2 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF726 PF05277.7 EAQ83915.1 - 1.8e-99 332.9 0.1 3.6e-99 331.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF726) SNAP PF14938.1 EAQ83917.1 - 3.2e-104 348.0 8.4 3.8e-104 347.8 5.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EAQ83917.1 - 1.5e-06 27.5 6.9 0.57 10.1 0.0 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ83917.1 - 4.3e-06 26.5 9.7 0.0051 16.7 0.5 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ83917.1 - 0.00013 21.5 10.5 4.9 7.3 0.1 6.6 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ83917.1 - 0.015 14.9 11.0 5.1 6.8 0.1 4.1 1 1 2 3 3 3 0 TPR repeat TPR_16 PF13432.1 EAQ83917.1 - 0.019 15.6 9.3 3.4 8.4 0.0 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.2 EAQ83917.1 - 0.028 13.1 4.1 0.024 13.2 0.8 1.9 1 1 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit NSF PF02071.15 EAQ83917.1 - 0.08 13.5 15.5 1.7 9.5 0.8 5.8 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.1 EAQ83917.1 - 5.8 6.9 9.4 24 5.0 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat NUC173 PF08161.7 EAQ83918.1 - 7.1e-81 270.2 0.0 4.4e-77 257.9 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.17 EAQ83918.1 - 0.011 15.7 0.3 11 6.4 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 EAQ83918.1 - 0.016 15.4 6.1 2 8.7 0.2 4.5 4 0 0 4 4 4 0 HEAT repeats Pkinase PF00069.20 EAQ83920.1 - 5.5e-57 192.8 0.0 9e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83920.1 - 5.3e-35 120.7 0.0 8.1e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ83920.1 - 3.5e-05 22.9 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ83920.1 - 0.00011 21.9 2.5 0.0058 16.3 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family FHA PF00498.21 EAQ83920.1 - 0.00022 21.2 0.0 0.00064 19.7 0.0 1.9 1 0 0 1 1 1 1 FHA domain RIO1 PF01163.17 EAQ83920.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EAQ83920.1 - 0.0022 17.0 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Amino_oxidase PF01593.19 EAQ83922.1 - 8.1e-17 61.4 0.4 2.7e-15 56.4 0.3 2.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ83922.1 - 2.3e-12 46.7 0.0 5.9e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAQ83922.1 - 1.5e-06 28.0 0.0 0.0063 16.2 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAQ83922.1 - 1.1e-05 25.6 0.1 0.0035 17.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ83922.1 - 1.3e-05 24.3 0.8 0.0039 16.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ83922.1 - 0.00047 20.0 0.0 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ83922.1 - 0.0051 15.3 0.1 2.1 6.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EAQ83922.1 - 0.052 12.6 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ83922.1 - 0.066 12.0 0.2 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EAQ83922.1 - 0.081 13.3 0.2 5 7.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ83922.1 - 0.12 11.1 0.1 0.22 10.3 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A CtaG_Cox11 PF04442.9 EAQ83923.1 - 9.6e-54 181.3 0.0 1.3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 L51_S25_CI-B8 PF05047.11 EAQ83925.1 - 2e-23 81.8 0.0 4.9e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PMT PF02366.13 EAQ83926.1 - 2.3e-59 200.7 14.8 1e-58 198.6 8.8 3.2 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EAQ83926.1 - 3.5e-35 121.2 0.3 4.8e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 EAQ83926.1 - 0.14 11.6 4.8 0.098 12.1 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ras PF00071.17 EAQ83927.1 - 3.5e-49 166.2 0.0 2.6e-38 130.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAQ83927.1 - 2.1e-16 60.4 0.0 1.8e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ83927.1 - 2e-07 30.4 0.0 7.5e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ83927.1 - 1.3e-05 24.7 0.0 5.1e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ83927.1 - 5.8e-05 22.3 0.0 0.00019 20.6 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ83927.1 - 0.0006 19.7 0.0 0.0019 18.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EAQ83927.1 - 0.028 14.5 0.0 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAQ83927.1 - 0.12 12.3 0.2 0.43 10.5 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain HpaP PF09483.5 EAQ83927.1 - 3.8 7.4 11.1 0.31 10.9 0.8 2.2 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Choline_transpo PF04515.7 EAQ83928.1 - 8.7e-13 47.7 29.8 3.7e-11 42.3 15.3 2.7 3 0 0 3 3 3 2 Plasma-membrane choline transporter WW PF00397.21 EAQ83929.1 - 7.7e-08 32.0 7.3 1.6e-07 31.0 5.1 1.5 1 0 0 1 1 1 1 WW domain CCDC50_N PF15295.1 EAQ83929.1 - 0.33 10.8 1.4 0.49 10.3 0.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF2012 PF09430.5 EAQ83930.1 - 6.6e-22 77.6 0.0 9.7e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Cys_Met_Meta_PP PF01053.15 EAQ83931.1 - 5.1e-149 495.7 0.0 5.8e-149 495.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EAQ83931.1 - 2.9e-12 46.3 0.9 2.9e-12 46.3 0.6 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EAQ83931.1 - 1.4e-08 34.0 0.1 3.6e-08 32.7 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EAQ83931.1 - 2.9e-08 32.8 0.3 5.5e-08 31.9 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAQ83931.1 - 3.1e-06 26.5 0.0 5.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EAQ83931.1 - 0.0013 17.1 0.1 0.0017 16.7 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EAQ83931.1 - 0.02 13.6 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein MARVEL PF01284.18 EAQ83932.1 - 6.7e-11 42.1 13.1 1.7e-08 34.4 9.1 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF2374 PF09574.5 EAQ83932.1 - 0.46 10.1 0.1 0.46 10.1 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (Duf2374) AMP-binding PF00501.23 EAQ83933.1 - 1.1e-80 271.0 0.0 1.4e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.27 EAQ83934.1 - 5.3e-06 26.1 9.6 0.02 14.7 0.3 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat RRM_1 PF00076.17 EAQ83935.1 - 3.8e-07 29.6 0.1 6.6e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ83935.1 - 1.3e-06 28.1 0.1 2.7e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ83935.1 - 1.8e-05 24.6 0.1 4.4e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EAQ83935.1 - 0.0022 18.1 0.0 0.007 16.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 EAQ83936.1 - 1.9e-104 349.2 0.0 2.3e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EAQ83936.1 - 0.0079 15.6 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Eclosion hormone Mito_carr PF00153.22 EAQ83937.1 - 1.7e-24 85.3 3.7 2.1e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 EAQ83939.1 - 2.5e-62 209.9 6.5 2.5e-62 209.9 4.5 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ83939.1 - 2.2e-23 83.7 0.0 4e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAQ83939.1 - 2.2e-13 50.8 0.0 5.9e-13 49.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAQ83939.1 - 8.6e-11 41.1 0.0 2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EAQ83939.1 - 0.0013 18.3 0.1 0.0028 17.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ83939.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Chorion_2 PF03964.10 EAQ83940.1 - 0.012 16.1 2.9 0.038 14.5 1.2 2.4 2 0 0 2 2 2 0 Chorion family 2 PmbA_TldD PF01523.11 EAQ83940.1 - 0.044 13.0 0.1 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase PepSY_2 PF13670.1 EAQ83940.1 - 0.062 13.2 0.3 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Nic96 PF04097.9 EAQ83941.1 - 4.7e-220 731.8 0.0 6.4e-220 731.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EAQ83941.1 - 4.4e-05 23.6 40.0 4.4e-05 23.6 27.7 6.8 6 1 1 7 7 7 1 Nucleoporin FG repeat region bZIP_1 PF00170.16 EAQ83941.1 - 0.018 15.0 8.0 0.057 13.3 5.5 1.9 1 0 0 1 1 1 0 bZIP transcription factor Adenylsucc_synt PF00709.16 EAQ83941.1 - 0.2 10.3 0.4 0.33 9.5 0.3 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase FGGY_C PF02782.11 EAQ83942.1 - 4.2e-51 173.3 0.2 6.4e-51 172.7 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAQ83942.1 - 1.4e-19 70.4 0.3 1.5e-16 60.5 0.0 3.0 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EAQ83942.1 - 0.023 14.0 0.2 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family SMN PF06003.7 EAQ83943.1 - 1.8 7.6 9.6 5.9 5.9 0.0 3.6 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) 4F5 PF04419.9 EAQ83945.1 - 4.3e-10 40.1 12.9 4.3e-10 40.1 9.0 2.5 2 1 1 3 3 3 1 4F5 protein family CAP_N PF01213.14 EAQ83945.1 - 0.18 11.0 2.4 0.2 10.9 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Claudin_2 PF13903.1 EAQ83947.1 - 1.3 8.7 7.8 0.33 10.6 0.6 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Myosin_head PF00063.16 EAQ83948.1 - 7.3e-11 40.8 0.0 9.8e-11 40.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) CFIA_Pcf11 PF11526.3 EAQ83948.1 - 4.6e-05 23.4 0.0 9.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 EAQ83948.1 - 0.00093 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRN7 PF11781.3 EAQ83948.1 - 0.027 13.9 2.7 0.4 10.2 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_2 PF13639.1 EAQ83948.1 - 0.043 13.6 0.1 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Ring finger domain zf-C2H2_4 PF13894.1 EAQ83948.1 - 0.17 12.2 4.7 2.4 8.6 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EAQ83948.1 - 5.9 6.6 8.4 8.9 6.1 1.1 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type GFO_IDH_MocA PF01408.17 EAQ83949.1 - 6.4e-20 71.8 0.3 1.3e-19 70.9 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EAQ83949.1 - 0.006 16.9 0.3 0.01 16.1 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EAQ83950.1 - 9.8e-10 38.8 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ83950.1 - 9.1e-06 26.2 0.2 1.7e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ83950.1 - 1.9e-05 24.9 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ83950.1 - 2.7e-05 24.5 0.0 8.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ83950.1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ83950.1 - 0.001 18.6 0.1 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Myb_DNA-binding PF00249.26 EAQ83951.1 - 1.4e-10 41.0 3.1 5.4e-08 32.7 0.0 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ83951.1 - 1.1e-05 25.3 3.8 0.0056 16.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EAQ83953.1 - 3.6e-22 77.8 1.0 5.5e-22 77.2 0.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EAQ83953.1 - 3e-19 69.0 0.0 6.4e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.18 EAQ83953.1 - 0.00059 19.1 0.0 0.0015 17.8 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin family zf-RING_2 PF13639.1 EAQ83954.1 - 2.1e-13 49.8 4.8 3.5e-13 49.1 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAQ83954.1 - 3.3e-07 29.8 3.1 5.5e-07 29.1 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAQ83954.1 - 4.7e-07 29.8 0.9 8.3e-07 29.0 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAQ83954.1 - 6.3e-06 26.1 5.3 1.1e-05 25.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ83954.1 - 1.2e-05 24.9 1.7 2e-05 24.2 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAQ83954.1 - 0.00057 19.5 1.7 0.0011 18.6 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAQ83954.1 - 0.0066 16.2 1.1 0.012 15.3 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EAQ83954.1 - 0.11 12.0 2.4 0.19 11.3 1.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EAQ83954.1 - 0.22 11.5 2.0 0.38 10.7 1.4 1.4 1 0 0 1 1 1 0 RING-like domain CAF-1_p150 PF11600.3 EAQ83954.1 - 2 7.7 4.4 3.5 6.9 3.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_cc PF11790.3 EAQ83955.1 - 6.7e-61 205.7 0.1 9.3e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Amidoligase_2 PF12224.3 EAQ83956.1 - 2.3e-16 60.2 0.0 3.9e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Putative amidoligase enzyme DUF643 PF04867.7 EAQ83956.1 - 0.056 13.8 0.2 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF643) Zn_clus PF00172.13 EAQ83958.1 - 3.2e-08 33.3 9.4 6e-08 32.4 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ83958.1 - 0.0034 16.0 0.1 0.0056 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain LPAM_2 PF13627.1 EAQ83959.1 - 0.51 10.1 4.7 1.3 8.7 3.2 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site 6PF2K PF01591.13 EAQ83960.1 - 5.2e-70 234.9 0.0 1.2e-49 168.4 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EAQ83960.1 - 3e-25 89.1 0.1 1e-24 87.4 0.0 2.0 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EAQ83960.1 - 3.3e-07 30.2 0.0 1.3e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ83960.1 - 0.0086 16.8 0.1 0.052 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EAQ83960.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CARD PF00619.16 EAQ83960.1 - 0.048 13.4 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Caspase recruitment domain Sigma70_r4_2 PF08281.7 EAQ83960.1 - 0.14 11.6 0.2 2.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 PhoU PF01895.14 EAQ83960.1 - 0.15 12.4 0.4 0.4 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoU domain dCMP_cyt_deam_1 PF00383.17 EAQ83961.1 - 2.8e-10 39.7 0.3 5.1e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Na_H_Exchanger PF00999.16 EAQ83962.1 - 4.5e-32 111.0 12.8 5.4e-32 110.7 8.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ank PF00023.25 EAQ83963.1 - 5.4e-16 57.5 1.0 4.4e-09 35.7 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EAQ83963.1 - 2.2e-14 53.5 0.0 4.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ83963.1 - 3e-14 52.7 0.2 1.5e-11 44.1 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ83963.1 - 2.6e-12 46.8 0.3 1.6e-06 28.4 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) TIG PF01833.19 EAQ83963.1 - 2.9e-09 36.8 0.0 8.4e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.1 EAQ83963.1 - 3.6e-09 35.9 0.1 0.00012 21.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Peptidase_C97 PF05903.9 EAQ83965.1 - 1.5e-06 28.0 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EAQ83965.1 - 0.015 15.2 2.9 0.053 13.4 0.1 2.5 2 1 0 3 3 3 0 Lecithin retinol acyltransferase DUF3301 PF11743.3 EAQ83965.1 - 0.042 13.3 0.5 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) DUF778 PF05608.7 EAQ83965.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Velvet PF11754.3 EAQ83966.1 - 3e-66 222.9 0.0 4.3e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Velvet factor VTC PF09359.5 EAQ83968.1 - 8.9e-97 323.4 1.3 1.3e-96 322.9 0.9 1.2 1 0 0 1 1 1 1 VTC domain Mito_carr PF00153.22 EAQ83968.1 - 1.6e-50 168.7 1.0 4.1e-20 71.3 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein SPX PF03105.14 EAQ83968.1 - 2.7e-18 66.7 16.0 1.1e-09 38.5 1.9 4.0 2 1 1 3 3 3 2 SPX domain FlxA PF14282.1 EAQ83968.1 - 0.087 12.7 0.5 0.23 11.4 0.3 1.6 1 0 0 1 1 1 0 FlxA-like protein Glu_synthase PF01645.12 EAQ83970.1 - 4.9e-159 529.1 0.0 7.7e-159 528.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EAQ83970.1 - 5e-139 462.9 0.0 7e-139 462.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EAQ83970.1 - 1.5e-56 191.8 0.2 2.7e-56 190.9 0.1 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EAQ83970.1 - 1.7e-42 144.7 0.3 3.5e-42 143.7 0.2 1.6 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EAQ83970.1 - 3.2e-22 78.2 0.1 3.2e-22 78.2 0.0 1.8 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EAQ83970.1 - 2.1e-17 63.7 0.7 9.4e-17 61.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ83970.1 - 8.8e-11 42.2 0.7 0.00013 22.1 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ83970.1 - 3.2e-08 33.4 0.0 1.3e-07 31.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAQ83970.1 - 4.3e-07 30.2 2.0 9.7e-05 22.7 0.1 3.2 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EAQ83970.1 - 2.2e-05 23.7 0.1 3.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EAQ83970.1 - 2.4e-05 23.4 1.6 0.00025 20.0 0.1 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ83970.1 - 5.8e-05 21.7 0.5 0.00013 20.6 0.3 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EAQ83970.1 - 0.00023 20.1 0.9 0.00047 19.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EAQ83970.1 - 0.00091 19.4 1.4 0.52 10.5 0.1 3.1 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EAQ83970.1 - 0.001 18.6 1.0 0.0066 16.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EAQ83970.1 - 0.002 17.2 0.1 0.011 14.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EAQ83970.1 - 0.0029 16.7 0.1 0.0029 16.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EAQ83970.1 - 0.004 16.9 0.1 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EAQ83970.1 - 0.0073 15.4 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.14 EAQ83970.1 - 0.025 12.8 0.1 5.6 5.0 0.0 2.7 2 1 0 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EAQ83970.1 - 0.025 13.7 0.2 0.3 10.2 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.19 EAQ83970.1 - 0.068 12.6 0.4 1.3 8.4 0.1 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family AdoHcyase_NAD PF00670.16 EAQ83970.1 - 0.15 11.9 3.6 3.2 7.5 0.0 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GIDA PF01134.17 EAQ83970.1 - 3.3 6.4 6.0 0.23 10.3 0.1 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Apc15p PF05841.6 EAQ83971.1 - 5.3e-29 101.5 2.2 5.3e-29 101.5 1.6 2.7 3 1 0 3 3 3 1 Apc15p protein Attacin_C PF03769.10 EAQ83971.1 - 0.33 11.1 1.7 2.8 8.1 0.2 2.3 2 0 0 2 2 2 0 Attacin, C-terminal region SNARE PF05739.14 EAQ83972.1 - 1.5e-08 34.1 2.4 2.1e-08 33.7 1.7 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EAQ83972.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sporozoite_P67 PF05642.6 EAQ83972.1 - 1.5 6.6 9.9 1.6 6.5 6.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1421 PF07223.6 EAQ83972.1 - 7.1 6.3 8.3 8.8 6.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) CHZ PF09649.5 EAQ83973.1 - 4.1e-16 57.9 1.7 1.6e-15 56.0 1.2 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ Cyclin PF08613.6 EAQ83974.1 - 1.1e-28 100.5 0.1 2.2e-28 99.5 0.0 1.7 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EAQ83974.1 - 6.4e-05 22.5 0.0 9.5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 EAQ83975.1 - 6.2e-08 32.1 8.8 2.1 8.3 0.3 9.4 10 1 1 11 11 11 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAQ83975.1 - 0.0027 17.9 3.7 2.8 8.3 0.0 5.6 5 2 0 5 5 5 2 HEAT repeats HEAT PF02985.17 EAQ83975.1 - 1.5 9.1 14.2 7 7.0 0.0 6.3 8 1 1 9 9 9 0 HEAT repeat Esterase PF00756.15 EAQ83976.1 - 0.04 13.3 0.1 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Putative esterase Bac_rhodopsin PF01036.13 EAQ83976.1 - 0.056 12.7 0.7 0.066 12.5 0.5 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein SirB PF04247.7 EAQ83976.1 - 0.065 12.9 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF2232 PF09991.4 EAQ83976.1 - 0.066 12.2 0.2 0.075 12.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF998 PF06197.8 EAQ83976.1 - 0.081 12.2 3.4 3.5 6.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) RRM_1 PF00076.17 EAQ83978.1 - 4.6e-14 51.7 0.0 1.2e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ83978.1 - 4.6e-12 45.7 0.0 8.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ83978.1 - 3.7e-09 36.2 0.0 7.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-F_leu_zip PF10473.4 EAQ83979.1 - 0.012 15.4 59.9 0.42 10.4 14.7 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EAQ83979.1 - 0.33 10.0 11.9 1.9 7.5 1.2 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 EAQ83979.1 - 0.47 9.8 53.3 1.9 7.9 14.2 2.3 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.7 EAQ83979.1 - 5.9 7.2 20.3 0.88 9.8 2.1 5.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Maf_N PF08383.6 EAQ83980.1 - 0.00029 20.3 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 Maf N-terminal region CHD5 PF04420.9 EAQ83981.1 - 3.8e-62 208.6 2.7 5.2e-62 208.2 1.9 1.2 1 0 0 1 1 1 1 CHD5-like protein PV-1 PF06637.6 EAQ83981.1 - 0.013 14.1 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) YPEB PF14620.1 EAQ83981.1 - 0.12 11.3 1.1 0.16 10.9 0.8 1.1 1 0 0 1 1 1 0 YpeB sporulation PPTA PF01239.17 EAQ83982.1 - 1.2e-05 24.4 12.7 0.028 13.7 0.3 4.7 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat Aa_trans PF01490.13 EAQ83983.1 - 2.4e-76 256.8 20.0 3.3e-76 256.3 13.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Asp PF00026.18 EAQ83983.1 - 1.3e-67 228.3 2.9 1.7e-67 227.9 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ83983.1 - 8.4e-10 38.8 0.4 8.4e-10 38.8 0.3 2.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAQ83983.1 - 0.00044 19.8 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EAQ83983.1 - 0.0044 17.4 0.0 0.49 10.9 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EAQ83983.1 - 0.059 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Ras PF00071.17 EAQ83984.1 - 5.8e-54 181.8 0.0 6.9e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ83984.1 - 5e-14 52.8 0.0 1e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ83984.1 - 1.8e-06 27.3 0.0 3.7e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAQ83984.1 - 0.00018 20.7 0.0 0.00057 19.1 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EAQ83984.1 - 0.017 14.5 0.1 0.1 11.9 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ83984.1 - 0.041 13.0 0.0 0.047 12.8 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.24 EAQ83985.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 KOW motif YajC PF02699.10 EAQ83985.1 - 0.055 13.1 0.2 0.16 11.6 0.2 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit AKAP7_NLS PF10469.4 EAQ83987.1 - 7.3e-11 42.1 0.0 4.2e-06 26.6 0.0 2.6 3 0 0 3 3 3 2 AKAP7 2'5' RNA ligase-like domain TMF_TATA_bd PF12325.3 EAQ83987.1 - 0.086 12.5 7.2 1.7 8.3 0.1 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Lebercilin PF15619.1 EAQ83987.1 - 0.097 12.0 2.2 0.13 11.6 0.2 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF605 PF04652.11 EAQ83987.1 - 0.7 9.2 19.2 1.2 8.5 13.3 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EAQ83987.1 - 1.8 8.3 4.8 2.8 7.7 3.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hpt PF01627.18 EAQ83988.1 - 4.1e-13 49.1 0.1 6e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Hpt domain DUF3984 PF13136.1 EAQ83990.1 - 2.2e-75 253.9 12.4 3.3e-75 253.3 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) IKI3 PF04762.7 EAQ83991.1 - 1.4e-301 1002.7 0.0 9.1e-171 569.8 0.0 2.1 1 1 1 2 2 2 2 IKI3 family Clathrin PF00637.15 EAQ83991.1 - 0.068 12.7 2.8 5.1 6.6 0.0 2.6 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.12 EAQ83991.1 - 0.86 9.6 4.7 1.6 8.8 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ83991.1 - 0.91 9.2 3.4 1.3 8.7 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.15 EAQ83992.1 - 6.6e-09 34.2 0.3 5.7e-08 31.1 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein Pkinase PF00069.20 EAQ83993.1 - 9.4e-54 182.2 0.0 1.3e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ83993.1 - 4e-30 104.7 0.0 6.2e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAQ83993.1 - 0.035 12.9 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EAQ83993.1 - 0.3 10.6 0.7 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Stc1 PF12898.2 EAQ83995.1 - 6.7e-18 64.5 3.5 1e-17 63.9 2.4 1.3 1 0 0 1 1 1 1 Stc1 domain DUF1777 PF08648.7 EAQ83996.1 - 0.00049 19.8 47.6 0.00049 19.8 33.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1777) Sugar_tr PF00083.19 EAQ83997.1 - 1.7e-89 300.4 25.1 2e-89 300.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ83997.1 - 1.7e-18 66.4 35.3 2.4e-18 65.9 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LRS4 PF10422.4 EAQ83998.1 - 0.018 14.4 0.1 0.018 14.4 0.0 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 BCDHK_Adom3 PF10436.4 EAQ83999.1 - 1.7e-67 226.0 0.0 2.4e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EAQ83999.1 - 7.5e-18 64.2 0.0 2.2e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EAQ83999.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyridoxal_deC PF00282.14 EAQ84000.1 - 9.6e-19 67.0 0.0 1.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EAQ84000.1 - 8.5e-05 21.4 0.0 0.0002 20.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EAQ84000.1 - 0.0027 16.7 0.0 0.0062 15.6 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.7 EAQ84001.1 - 1.4e-67 227.6 0.0 1.8e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EAQ84001.1 - 3.8e-06 26.3 0.0 0.022 14.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.2 EAQ84002.1 - 3.9e-09 36.4 4.2 6.8e-09 35.6 0.6 2.2 2 0 0 2 2 2 1 RING-variant domain zf-Sec23_Sec24 PF04810.10 EAQ84002.1 - 0.018 14.6 0.8 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.1 EAQ84002.1 - 0.023 14.5 2.4 0.023 14.5 1.7 2.1 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.24 EAQ84002.1 - 7 6.4 8.8 1.6 8.4 3.6 1.7 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 EAQ84003.1 - 1.9e-51 174.0 0.0 1.9e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EAQ84003.1 - 8.9e-06 24.9 1.5 1e-05 24.7 0.2 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.21 EAQ84004.1 - 1.5e-31 109.2 0.0 2.3e-20 73.1 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EAQ84004.1 - 4.5e-18 65.4 0.0 1e-09 38.4 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.26 EAQ84004.1 - 1.1e-17 63.6 0.1 7.1e-17 61.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EAQ84004.1 - 5.8e-16 58.0 0.1 1.3e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Rgp1 PF08737.5 EAQ84005.1 - 3.5e-125 418.3 0.0 6.2e-125 417.5 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EAQ84005.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LicD PF04991.8 EAQ84006.1 - 2.9e-35 122.2 0.2 1.2e-33 116.9 0.2 2.1 1 1 0 1 1 1 1 LicD family Arfaptin PF06456.8 EAQ84007.1 - 0.008 15.5 6.0 0.014 14.7 4.1 1.3 1 0 0 1 1 1 1 Arfaptin-like domain TBPIP PF07106.8 EAQ84007.1 - 0.019 14.5 5.1 0.035 13.6 3.5 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Matrilin_ccoil PF10393.4 EAQ84007.1 - 0.028 13.7 9.0 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Prominin PF05478.6 EAQ84007.1 - 0.086 10.3 10.9 0.12 9.8 7.6 1.0 1 0 0 1 1 1 0 Prominin FH2 PF02181.18 EAQ84007.1 - 0.11 11.3 3.7 0.18 10.6 2.6 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain IFT57 PF10498.4 EAQ84007.1 - 0.33 9.6 9.8 0.59 8.8 6.8 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF972 PF06156.8 EAQ84007.1 - 0.39 11.0 7.9 0.13 12.6 3.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EAQ84007.1 - 0.57 9.9 5.8 0.57 9.9 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 EAQ84007.1 - 0.64 9.1 6.8 0.2 10.8 2.8 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rifin_STEVOR PF02009.11 EAQ84007.1 - 0.67 9.5 10.2 0.83 9.2 5.2 1.8 1 1 1 2 2 2 0 Rifin/stevor family DUF3584 PF12128.3 EAQ84007.1 - 1.2 6.4 28.7 1.6 5.9 19.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 EAQ84007.1 - 5 7.2 12.5 0.84 9.7 5.4 1.9 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family T2SF PF00482.18 EAQ84007.1 - 6.8 6.6 16.5 1.9 8.3 3.6 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DivIVA PF05103.8 EAQ84007.1 - 9.4 6.2 26.3 6.6 6.8 9.4 2.3 1 1 1 2 2 2 0 DivIVA protein ER_lumen_recept PF00810.13 EAQ84008.1 - 4.8e-55 186.1 8.1 8.6e-55 185.2 5.6 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EAQ84008.1 - 0.0013 18.2 7.3 0.052 13.0 0.1 3.7 3 1 1 4 4 4 2 PQ loop repeat Rep_fac_C PF08542.6 EAQ84009.1 - 8.6e-24 83.3 0.1 2.3e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EAQ84009.1 - 7.8e-12 45.1 0.0 1.5e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EAQ84009.1 - 1.6e-06 28.3 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ84009.1 - 5.9e-06 26.4 0.7 0.00013 22.1 0.2 2.9 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ84009.1 - 3.4e-05 23.9 2.5 0.018 15.0 0.6 3.2 2 2 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EAQ84009.1 - 0.0011 18.9 0.3 0.044 13.8 0.2 2.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EAQ84009.1 - 0.0013 18.6 0.1 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EAQ84009.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF2861 PF11060.3 EAQ84009.1 - 0.024 13.9 0.1 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) Arch_ATPase PF01637.13 EAQ84009.1 - 0.033 13.8 0.1 0.075 12.7 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 EAQ84009.1 - 0.037 12.7 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T4SS-DNA_transf PF02534.9 EAQ84009.1 - 0.06 11.9 0.1 0.14 10.6 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EAQ84009.1 - 0.078 11.7 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EAQ84009.1 - 0.11 11.9 0.2 1.4 8.3 0.0 2.3 2 1 0 3 3 3 0 AAA-like domain AAA_5 PF07728.9 EAQ84009.1 - 0.13 12.0 0.5 0.62 9.7 0.3 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EAQ84009.1 - 0.14 12.4 0.1 0.29 11.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EAQ84009.1 - 0.25 10.9 1.4 0.92 9.0 1.0 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.13 EAQ84010.1 - 8.9e-31 106.3 0.5 1.1e-30 106.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e 5-FTHF_cyc-lig PF01812.15 EAQ84010.1 - 0.045 13.5 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family RFC1 PF08519.7 EAQ84011.1 - 2.3e-58 196.3 0.1 4.9e-58 195.2 0.0 1.6 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EAQ84011.1 - 3.2e-12 46.4 0.0 9.8e-12 44.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EAQ84011.1 - 2.4e-09 37.4 0.0 6.7e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EAQ84011.1 - 5.7e-07 28.5 0.0 1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EAQ84011.1 - 1.7e-05 25.6 3.6 2.1e-05 25.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain DNA_pol3_delta PF06144.8 EAQ84011.1 - 6.9e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EAQ84011.1 - 0.00023 21.3 0.0 0.00097 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ84011.1 - 0.00033 20.3 0.1 0.0009 18.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EAQ84011.1 - 0.0012 19.1 4.4 0.0018 18.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EAQ84011.1 - 0.005 16.8 0.0 0.057 13.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EAQ84011.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAQ84011.1 - 0.027 14.1 0.0 0.071 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EAQ84011.1 - 0.035 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 EAQ84011.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ84011.1 - 0.063 13.2 3.6 0.08 12.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 EAQ84011.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EAQ84011.1 - 0.11 12.1 0.0 0.98 9.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain GrpE PF01025.14 EAQ84012.1 - 4e-39 133.8 6.7 5.3e-39 133.4 4.7 1.1 1 0 0 1 1 1 1 GrpE RNA_pol_A_bac PF01000.21 EAQ84013.1 - 9.3e-31 106.2 0.0 1.5e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EAQ84013.1 - 7e-16 57.1 0.0 8.7e-16 56.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EAQ84013.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF22 Mito_carr PF00153.22 EAQ84014.1 - 3.1e-30 103.7 0.1 3.4e-15 55.5 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein FDX-ACB PF03147.9 EAQ84015.1 - 1.5e-25 89.2 0.0 2.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.15 EAQ84015.1 - 1.5e-20 73.4 0.1 3.7e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Calcipressin PF04847.7 EAQ84016.1 - 3.6e-49 166.8 0.3 4.8e-49 166.4 0.2 1.1 1 0 0 1 1 1 1 Calcipressin Neugrin PF06413.6 EAQ84017.1 - 2e-11 44.1 0.8 3.4e-11 43.4 0.6 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EAQ84017.1 - 3.3e-05 23.8 7.4 3.3e-05 23.8 5.1 2.0 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 EAQ84017.1 - 0.022 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 HTH domain DUF955 PF06114.8 EAQ84017.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Sigma70_r4 PF04545.11 EAQ84017.1 - 0.08 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 WD40 PF00400.27 EAQ84018.1 - 4.8e-19 67.4 1.3 7.2e-05 22.5 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 EAQ84018.1 - 0.25 9.5 0.5 10 4.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) VID27 PF08553.5 EAQ84018.1 - 0.51 8.5 0.5 2.5 6.2 0.1 2.0 1 1 1 2 2 2 0 VID27 cytoplasmic protein FoP_duplication PF13865.1 EAQ84018.1 - 0.85 10.1 9.1 1.4 9.4 0.9 2.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 WLM PF08325.5 EAQ84019.1 - 4.9e-42 143.8 0.0 7.6e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EAQ84019.1 - 4.8e-05 23.2 1.4 9e-05 22.3 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EAQ84019.1 - 0.016 14.8 0.4 0.023 14.3 0.3 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 EAQ84019.1 - 0.051 13.6 0.1 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Peptidase MA superfamily Reprolysin_5 PF13688.1 EAQ84019.1 - 0.065 13.1 0.6 0.12 12.3 0.4 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Glyco_hydro_72 PF03198.9 EAQ84020.1 - 1.7e-116 388.6 0.2 2.1e-116 388.3 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase ATP-grasp_2 PF08442.5 EAQ84021.1 - 4.7e-06 26.1 0.0 1.2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EAQ84022.1 - 1.5e-18 66.6 0.0 7e-16 57.9 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EAQ84022.1 - 4e-18 65.7 0.1 1.2e-17 64.1 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EAQ84022.1 - 1.8e-15 56.8 0.1 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EAQ84022.1 - 5e-06 26.1 0.0 0.00023 20.7 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EAQ84022.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain MRG PF05712.8 EAQ84023.1 - 1.3e-33 115.5 0.3 2.2e-33 114.7 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EAQ84023.1 - 2e-05 24.1 0.8 4e-05 23.2 0.6 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EAQ84023.1 - 0.11 12.1 0.7 0.26 10.9 0.5 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 EAQ84024.1 - 5.9e-28 96.3 0.9 1.1e-27 95.5 0.6 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Ribosomal_60s PF00428.14 EAQ84025.1 - 2.6 8.5 9.9 19 5.7 0.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein AT_hook PF02178.14 EAQ84026.1 - 0.00092 18.6 44.5 0.015 14.8 3.1 4.6 4 0 0 4 4 4 3 AT hook motif NB-ARC PF00931.17 EAQ84027.1 - 0.0001 21.3 0.0 0.00063 18.6 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 EAQ84027.1 - 0.00011 22.0 0.4 0.00041 20.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_25 PF13481.1 EAQ84027.1 - 0.0042 16.5 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAQ84027.1 - 0.017 14.7 0.0 0.042 13.5 0.0 1.6 1 1 0 1 1 1 0 NACHT domain TPR_12 PF13424.1 EAQ84027.1 - 0.035 14.0 0.2 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Mus7 PF09462.5 EAQ84027.1 - 0.047 12.5 0.1 0.065 12.0 0.1 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family AAA_17 PF13207.1 EAQ84027.1 - 0.089 13.6 0.1 0.29 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAQ84027.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain tRNA_U5-meth_tr PF05958.6 EAQ84029.1 - 4.5e-08 32.1 0.0 3.8e-07 29.1 0.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EAQ84029.1 - 2e-06 27.5 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAQ84029.1 - 0.00056 19.1 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRAM PF01938.15 EAQ84029.1 - 0.00085 19.0 0.1 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 EAQ84029.1 - 0.0016 18.9 0.0 0.0039 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ84029.1 - 0.0022 17.9 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAQ84029.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Glycos_transf_1 PF00534.15 EAQ84030.1 - 1.2e-18 67.1 0.0 2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAQ84030.1 - 2e-09 37.6 0.1 4.4e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF605 PF04652.11 EAQ84031.1 - 0.49 9.7 10.6 0.62 9.3 7.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF2360 PF10152.4 EAQ84031.1 - 1.9 8.7 4.8 3.4 7.9 3.3 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Syntaxin_2 PF14523.1 EAQ84032.1 - 3.1e-26 91.3 1.1 3.1e-26 91.3 0.8 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EAQ84032.1 - 1.6e-18 66.1 3.5 4e-18 64.8 2.4 1.7 1 0 0 1 1 1 1 SNARE domain Vac_Fusion PF02346.11 EAQ84032.1 - 0.00024 20.4 0.0 0.00077 18.8 0.0 1.8 1 0 0 1 1 1 1 Chordopoxvirus fusion protein MCPsignal PF00015.16 EAQ84032.1 - 0.012 15.1 3.7 0.051 13.1 0.2 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EAQ84032.1 - 0.022 14.3 0.1 0.07 12.7 0.1 1.9 1 0 0 1 1 1 0 Synaptobrevin DUF883 PF05957.8 EAQ84032.1 - 0.024 15.0 8.3 0.63 10.4 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF651 PF04895.7 EAQ84032.1 - 0.11 12.0 0.5 0.7 9.5 0.1 2.2 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) DUF1664 PF07889.7 EAQ84032.1 - 0.15 11.8 2.8 6 6.6 0.5 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2951 PF11166.3 EAQ84032.1 - 0.26 11.1 3.2 0.51 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF948 PF06103.6 EAQ84032.1 - 0.43 10.4 2.3 7.5 6.4 0.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) EspB PF05802.6 EAQ84032.1 - 0.46 9.3 6.1 0.047 12.6 0.7 1.8 2 0 0 2 2 2 0 Enterobacterial EspB protein Ndc1_Nup PF09531.5 EAQ84033.1 - 3.2e-157 524.5 0.0 3.6e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF4129 PF13559.1 EAQ84034.1 - 0.0032 17.3 0.1 0.0075 16.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.6 EAQ84034.1 - 0.026 14.0 0.2 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 NICE-3 protein ICL PF00463.16 EAQ84035.1 - 0.14 10.3 0.3 0.18 9.9 0.2 1.1 1 0 0 1 1 1 0 Isocitrate lyase family FAD_binding_3 PF01494.14 EAQ84037.1 - 1.2e-72 244.9 0.0 1.6e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EAQ84037.1 - 4.9e-45 153.1 0.0 8.2e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EAQ84037.1 - 0.0007 19.9 0.0 0.0035 17.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ84037.1 - 0.0068 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ84037.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.1 EAQ84037.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_8 PF13450.1 EAQ84037.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ84037.1 - 0.029 13.2 0.0 0.07 12.0 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EAQ84037.1 - 0.058 11.8 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 EAQ84037.1 - 0.086 12.2 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EAQ84037.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EAQ84037.1 - 0.12 11.7 0.2 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 EAQ84038.1 - 2.8e-24 85.4 0.1 4.7e-23 81.3 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain MAP65_ASE1 PF03999.7 EAQ84038.1 - 3.9 5.9 6.6 0.14 10.7 0.2 1.7 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Fungal_trans_2 PF11951.3 EAQ84039.1 - 1.1e-46 159.2 0.0 1e-23 83.6 0.0 3.1 2 1 1 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ84039.1 - 3e-07 30.2 13.4 5.4e-07 29.4 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EphA2_TM PF14575.1 EAQ84040.1 - 0.0072 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 EAQ84040.1 - 0.08 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4083 PF13314.1 EAQ84040.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) IncA PF04156.9 EAQ84040.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 IncA protein HAMP PF00672.20 EAQ84040.1 - 0.14 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 HAMP domain P12 PF12669.2 EAQ84040.1 - 3.2 8.0 10.8 0.69 10.1 0.0 3.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Abhydrolase_3 PF07859.8 EAQ84042.1 - 6.4e-33 114.1 0.0 4.9e-22 78.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EAQ84042.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans PF04082.13 EAQ84048.1 - 4.2e-23 81.5 0.0 8.8e-23 80.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ84048.1 - 6.6e-08 32.3 12.7 1.3e-07 31.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SCRL PF06876.7 EAQ84051.1 - 0.12 12.3 2.4 0.21 11.5 1.7 1.3 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein Dicty_REP PF05086.7 EAQ84051.1 - 2.4 5.7 3.7 2.8 5.5 2.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pyridoxal_deC PF00282.14 EAQ84052.1 - 9e-73 244.8 0.0 1.2e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PXT1 PF15214.1 EAQ84052.1 - 0.043 14.0 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Drf_GBD PF06371.8 EAQ84052.1 - 0.11 11.8 0.1 5.8 6.2 0.4 2.2 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Aminotran_3 PF00202.16 EAQ84053.1 - 1.4e-72 244.4 0.0 1.8e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Chitin_bind_3 PF03067.10 EAQ84054.1 - 0.075 13.2 0.7 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 Chitin binding domain LsmAD PF06741.8 EAQ84056.1 - 1.3e-21 76.4 1.8 3.5e-21 75.0 1.3 1.8 1 0 0 1 1 1 1 LsmAD domain DUF4611 PF15387.1 EAQ84057.1 - 1.5 8.9 4.9 2.7 8.2 3.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) AIP3 PF03915.8 EAQ84058.1 - 1.4e-150 501.9 11.9 1.2e-107 360.5 5.3 2.2 1 1 1 2 2 2 2 Actin interacting protein 3 AAA_13 PF13166.1 EAQ84058.1 - 0.34 9.3 1.6 0.77 8.1 1.1 1.6 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EAQ84058.1 - 0.99 9.2 6.0 1.4 8.7 0.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EAQ84058.1 - 1 8.8 6.6 9.7 5.7 0.2 3.3 3 0 0 3 3 3 0 Septum formation initiator TraF_2 PF13729.1 EAQ84058.1 - 1.1 7.9 5.6 2.4 6.8 0.2 2.7 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein NPV_P10 PF05531.7 EAQ84058.1 - 1.6 8.9 7.1 2.5 8.4 0.4 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Beta-lactamase PF00144.19 EAQ84059.1 - 7.8e-37 127.0 0.1 1.2e-36 126.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2782 PF11191.3 EAQ84060.1 - 0.11 12.4 1.0 0.14 12.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) FAP PF07174.6 EAQ84060.1 - 0.42 9.8 5.8 0.43 9.8 4.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Myb_DNA-binding PF00249.26 EAQ84061.1 - 7.5e-09 35.5 0.1 0.00016 21.6 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.12 EAQ84062.1 - 4e-140 466.1 0.0 5e-140 465.8 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EAQ84062.1 - 0.056 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase HMGL-like PF00682.14 EAQ84063.1 - 6e-22 78.4 0.8 2.9e-06 27.1 0.0 3.2 2 1 1 3 3 3 3 HMGL-like DDE_3 PF13358.1 EAQ84063.1 - 5.6e-20 71.5 0.1 9.6e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EAQ84063.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain NACHT PF05729.7 EAQ84065.1 - 4.3e-05 23.2 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF573 PF04504.9 EAQ84065.1 - 0.0088 16.2 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF573 DUF605 PF04652.11 EAQ84065.1 - 0.041 13.2 19.0 0.071 12.4 13.1 1.3 1 0 0 1 1 1 0 Vta1 like BBS2_Mid PF14783.1 EAQ84065.1 - 0.05 13.3 0.0 5.3 6.8 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EAQ84065.1 - 0.057 13.7 0.1 0.34 11.2 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Fructosamin_kin PF03881.9 EAQ84066.1 - 1.8e-28 99.3 0.0 2.3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAQ84066.1 - 2.7e-07 30.5 0.1 4.3e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 EAQ84067.1 - 5.3e-31 107.6 6.7 9.3e-31 106.8 4.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ84067.1 - 1.2e-08 33.9 0.2 1.5e-08 33.6 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ84067.1 - 0.00065 18.0 3.8 0.00098 17.4 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Chromo PF00385.19 EAQ84068.1 - 9.1e-16 57.2 0.9 1.7e-15 56.4 0.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EAQ84069.1 - 0.00073 19.3 3.7 0.00073 19.3 2.6 2.8 2 0 0 2 2 2 1 Zinc knuckle PspA_IM30 PF04012.7 EAQ84069.1 - 0.0061 15.9 5.9 0.01 15.2 4.1 1.3 1 0 0 1 1 1 1 PspA/IM30 family COG2 PF06148.6 EAQ84069.1 - 0.0083 15.9 2.8 0.016 15.0 1.9 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EAQ84069.1 - 0.041 12.5 4.5 0.062 11.9 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EAQ84069.1 - 0.11 12.0 4.3 0.19 11.3 3.0 1.2 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EAQ84069.1 - 0.14 12.0 7.5 0.51 10.1 5.2 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF148 PF02520.12 EAQ84069.1 - 0.22 11.3 4.6 0.41 10.4 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.7 EAQ84069.1 - 0.26 11.0 5.9 0.58 9.8 4.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 EAQ84069.1 - 0.54 10.6 5.7 1.2 9.5 3.9 1.6 1 0 0 1 1 1 0 SlyX FlaC_arch PF05377.6 EAQ84069.1 - 2.4 8.1 5.7 0.51 10.2 0.9 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-CCHC_4 PF14392.1 EAQ84069.1 - 9.1 6.0 9.8 0.83 9.3 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle HA PF03457.9 EAQ84070.1 - 0.01 15.9 0.1 0.028 14.5 0.0 1.8 1 0 0 1 1 1 0 Helicase associated domain UvrD_C_2 PF13538.1 EAQ84070.1 - 0.032 14.3 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Pyridox_oxidase PF01243.15 EAQ84071.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase RAP1 PF07218.6 EAQ84071.1 - 4.3 5.3 4.7 4.3 5.3 3.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CTF_NFI PF00859.13 EAQ84072.1 - 0.0067 16.2 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region M60-like PF13402.1 EAQ84072.1 - 0.036 12.9 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase M60-like family NMT1 PF09084.6 EAQ84073.1 - 2.5e-09 37.0 0.0 8e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EAQ84073.1 - 6.6e-05 22.2 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.2 EAQ84073.1 - 0.0076 15.6 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Staph_haemo PF05480.6 EAQ84074.1 - 0.066 12.9 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein F-box-like_2 PF13013.1 EAQ84076.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain RVT_1 PF00078.22 EAQ84077.1 - 1.7e-32 112.5 0.0 3.7e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84077.1 - 0.00013 21.5 0.1 0.00036 20.1 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Glyco_transf_90 PF05686.7 EAQ84079.1 - 3.5e-07 29.2 0.0 0.00015 20.6 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ank PF00023.25 EAQ84080.1 - 4.7e-11 41.9 0.8 0.00011 21.8 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EAQ84080.1 - 2.1e-09 37.5 0.7 8.8e-07 29.1 0.1 3.5 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ84080.1 - 1e-07 31.9 3.6 0.00096 19.3 0.1 4.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84080.1 - 5.9e-06 26.0 1.0 0.003 17.6 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EAQ84080.1 - 7e-05 23.2 0.2 0.25 11.9 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Esterase_phd PF10503.4 EAQ84081.1 - 7.1e-23 80.9 0.2 1.1e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EAQ84081.1 - 3.4e-11 42.6 10.9 3.4e-11 42.6 7.6 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EAQ84081.1 - 9.1e-11 41.3 0.1 1.5e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ84081.1 - 3.4e-07 30.1 0.1 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ84081.1 - 0.00041 20.3 0.1 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ84081.1 - 0.0038 16.8 0.1 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAQ84081.1 - 0.037 13.4 0.1 0.16 11.3 0.1 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.23 EAQ84081.1 - 0.041 12.5 0.7 0.05 12.3 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ84081.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EAQ84081.1 - 0.12 11.5 0.3 0.23 10.7 0.2 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family SDA1 PF05285.7 EAQ84082.1 - 1e-87 294.4 31.8 1e-87 294.4 22.1 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EAQ84082.1 - 1.3e-20 73.3 0.2 3.6e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain bZIP_1 PF00170.16 EAQ84084.1 - 3.2e-07 30.2 3.8 3.2e-07 30.2 2.7 3.0 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ84084.1 - 0.0041 16.8 4.2 0.0041 16.8 2.9 3.5 3 0 0 3 3 3 1 Basic region leucine zipper AAA_30 PF13604.1 EAQ84086.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.1 EAQ84087.1 - 2.3e-25 89.1 0.0 2.9e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAQ84087.1 - 0.00029 20.4 0.1 0.0034 16.9 0.1 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EAQ84087.1 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Tyrosinase PF00264.15 EAQ84088.1 - 5.6e-27 95.3 1.4 9.1e-27 94.6 1.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF972 PF06156.8 EAQ84089.1 - 0.2 12.0 2.8 7.4 6.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF605 PF04652.11 EAQ84090.1 - 0.00049 19.6 12.1 0.00049 19.6 8.4 4.9 3 1 1 4 4 4 1 Vta1 like GCV_T PF01571.16 EAQ84093.1 - 3.1e-08 33.2 0.0 1.3e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EAQ84093.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DUF2076 PF09849.4 EAQ84093.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SAP PF02037.22 EAQ84094.1 - 2.5e-08 33.2 0.1 4.8e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 SAP domain Fungal_trans PF04082.13 EAQ84095.1 - 4.4e-19 68.3 0.0 7.3e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ84095.1 - 0.00011 22.0 7.8 0.00011 22.0 5.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mating_C PF12737.2 EAQ84095.1 - 0.78 8.5 13.4 1.5 7.6 9.3 1.4 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Herpes_UL6 PF01763.11 EAQ84097.1 - 0.003 15.8 0.9 0.0054 14.9 0.6 1.3 1 0 0 1 1 1 1 Herpesvirus UL6 like Pneumo_att_G PF05539.6 EAQ84097.1 - 8.2 5.6 13.8 0.17 11.1 0.2 2.3 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G DOCK-C2 PF14429.1 EAQ84099.1 - 6.6e-22 78.0 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EAQ84099.1 - 2.3e-08 33.5 0.0 4.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EAQ84099.1 - 0.002 17.4 0.0 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Chorismate_synt PF01264.16 EAQ84101.1 - 3.2e-127 423.7 0.0 1.2e-126 421.8 0.0 1.7 1 1 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.14 EAQ84102.1 - 1.2e-12 47.8 0.0 1.9e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Clathrin PF00637.15 EAQ84103.1 - 9e-21 73.9 3.6 1.7e-19 69.8 1.0 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EAQ84103.1 - 2e-20 72.3 0.6 5.9e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EAQ84103.1 - 0.00064 19.4 3.4 0.0014 18.3 2.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EAQ84103.1 - 0.0011 18.7 3.4 0.0011 18.7 2.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EAQ84103.1 - 0.099 12.4 1.3 0.23 11.2 0.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EAQ84103.1 - 0.1 12.4 1.0 0.29 10.9 0.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EAQ84103.1 - 0.17 11.5 5.9 0.025 14.2 1.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAQ84103.1 - 0.24 11.5 1.9 0.71 10.0 1.3 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAQ84103.1 - 0.28 11.2 7.7 0.22 11.5 2.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MutL_C PF08676.6 EAQ84104.1 - 5.7e-12 45.4 0.3 1.1e-09 38.0 0.0 2.9 2 1 1 3 3 3 2 MutL C terminal dimerisation domain Ribosomal_L27 PF01016.14 EAQ84106.1 - 0.067 12.9 0.2 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal L27 protein CN_hydrolase PF00795.17 EAQ84107.1 - 3.6e-13 49.2 0.0 4.6e-08 32.6 0.0 2.3 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase DUF1469 PF07332.6 EAQ84108.1 - 2.7 7.7 4.5 0.5 10.1 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) AA_permease_2 PF13520.1 EAQ84109.1 - 5.5e-32 110.8 40.8 2.3e-31 108.7 28.3 1.9 1 1 0 1 1 1 1 Amino acid permease Sortase PF04203.8 EAQ84110.1 - 0.12 11.9 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Sortase family Phage_lysozyme PF00959.14 EAQ84111.1 - 1e-15 57.9 0.1 1.7e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.6 EAQ84111.1 - 0.00027 21.0 3.4 0.00027 21.0 0.6 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain V-set PF07686.12 EAQ84111.1 - 0.061 13.2 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain CHAP PF05257.11 EAQ84112.1 - 5.9e-24 84.0 9.8 5.9e-24 84.0 6.8 1.6 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.6 EAQ84112.1 - 0.0013 18.9 0.7 0.0013 18.9 0.5 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Pollen_Ole_e_I PF01190.12 EAQ84112.1 - 0.11 12.2 1.7 0.21 11.4 1.2 1.5 1 0 0 1 1 1 0 Pollen proteins Ole e I like IU_nuc_hydro PF01156.14 EAQ84113.1 - 0.047 12.8 0.1 0.21 10.7 0.0 1.8 1 1 1 2 2 2 0 Inosine-uridine preferring nucleoside hydrolase Glyco_transf_15 PF01793.11 EAQ84116.1 - 1.5e-116 389.0 0.0 2.1e-116 388.4 0.0 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH_7 PF15408.1 EAQ84116.1 - 0.18 11.6 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 EAQ84118.1 - 1.3e-06 27.3 0.0 1.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytomega_US3 PF05963.6 EAQ84118.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus US3 protein adh_short PF00106.20 EAQ84119.1 - 3.2e-14 53.1 4.8 3.2e-14 53.1 3.4 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ84119.1 - 1.4e-10 41.0 2.3 2.6e-10 40.2 1.6 1.4 1 0 0 1 1 1 1 KR domain ABC2_membrane PF01061.19 EAQ84120.1 - 7.2e-62 208.2 51.2 1.9e-42 144.8 14.6 3.7 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EAQ84120.1 - 2.2e-27 96.0 0.0 9.9e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EAQ84120.1 - 1.5e-23 82.4 0.0 4.6e-23 80.8 0.0 1.9 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EAQ84120.1 - 7.7e-08 31.7 21.9 1.1e-06 27.9 11.7 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EAQ84120.1 - 3.3e-05 23.9 0.0 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EAQ84120.1 - 6.1e-05 22.2 0.0 0.0042 16.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAQ84120.1 - 0.00022 21.3 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ84120.1 - 0.0005 19.8 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EAQ84120.1 - 0.0016 18.4 0.0 0.037 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAQ84120.1 - 0.0035 17.6 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EAQ84120.1 - 0.0083 15.6 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EAQ84120.1 - 0.0084 15.6 0.0 0.048 13.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EAQ84120.1 - 0.0091 16.8 0.0 0.054 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ84120.1 - 0.019 14.7 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 EAQ84120.1 - 0.021 14.2 0.0 0.64 9.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EAQ84120.1 - 0.031 13.8 0.1 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EAQ84120.1 - 0.034 13.5 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EAQ84120.1 - 0.043 14.0 0.0 2.8 8.1 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EAQ84120.1 - 0.066 13.7 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Med25_SD1 PF11235.3 EAQ84120.1 - 0.087 13.1 1.5 0.17 12.1 1.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 AAA_33 PF13671.1 EAQ84120.1 - 0.089 12.6 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAQ84120.1 - 0.1 11.6 0.0 7.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 EAQ84120.1 - 0.14 12.0 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 EAQ84120.1 - 0.17 10.6 0.0 0.55 8.9 0.0 1.8 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 EAQ84120.1 - 0.21 10.7 0.1 21 4.3 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Fungal_trans PF04082.13 EAQ84121.1 - 2.6e-09 36.3 0.1 5.3e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ84121.1 - 2e-08 34.0 11.6 2e-08 34.0 8.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC37_C PF08564.5 EAQ84122.1 - 1.7e-24 85.5 1.6 2.4e-24 85.0 0.3 1.8 2 0 0 2 2 2 1 Cdc37 C terminal domain CDC37_M PF08565.6 EAQ84122.1 - 4.1e-18 65.4 0.0 6.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain ABC_tran PF00005.22 EAQ84122.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter TrwB_AAD_bind PF10412.4 EAQ84122.1 - 0.00073 18.2 0.0 0.18 10.3 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 EAQ84122.1 - 0.0031 17.0 0.0 0.009 15.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EAQ84122.1 - 0.0032 17.6 0.2 0.025 14.7 0.0 2.1 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ84122.1 - 0.0036 16.9 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 EAQ84122.1 - 0.0062 16.8 0.0 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ84122.1 - 0.0077 16.2 1.0 0.2 11.6 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EAQ84122.1 - 0.0081 15.7 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EAQ84122.1 - 0.0092 15.4 0.1 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EAQ84122.1 - 0.0092 15.1 0.0 0.11 11.6 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAQ84122.1 - 0.014 16.1 0.4 0.036 14.8 0.3 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAQ84122.1 - 0.019 15.1 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EAQ84122.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2335 PF10097.4 EAQ84122.1 - 0.093 12.3 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) DUF87 PF01935.12 EAQ84122.1 - 0.1 12.3 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EAQ84122.1 - 0.11 11.8 0.1 1 8.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Fer2_BFD PF04324.10 EAQ84122.1 - 0.14 12.2 0.2 0.43 10.6 0.1 2.0 1 1 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Arch_ATPase PF01637.13 EAQ84122.1 - 0.14 11.8 0.0 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase Herpes_Helicase PF02689.9 EAQ84122.1 - 0.22 9.2 0.0 0.42 8.2 0.0 1.4 2 0 0 2 2 2 0 Helicase E2R135 PF11570.3 EAQ84123.1 - 0.021 14.9 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 CBM_1 PF00734.13 EAQ84124.1 - 6.4e-13 48.1 11.7 1.6e-12 46.8 8.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Herpes_capsid PF06112.6 EAQ84124.1 - 5.2 7.1 9.2 14 5.6 6.4 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ABC_tran PF00005.22 EAQ84125.1 - 6.3e-21 75.1 0.3 6.3e-09 36.2 0.0 2.8 2 1 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EAQ84125.1 - 1.7e-18 67.0 11.0 3.2e-18 66.1 7.7 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EAQ84125.1 - 1.9e-06 27.2 0.0 0.0014 17.8 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EAQ84125.1 - 9.7e-06 25.7 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EAQ84125.1 - 0.00012 22.1 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAQ84125.1 - 0.00052 19.4 0.1 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EAQ84125.1 - 0.019 14.4 0.0 0.064 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EAQ84125.1 - 0.027 14.4 0.2 0.06 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAQ84125.1 - 0.027 13.9 0.1 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EAQ84125.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAQ84125.1 - 0.055 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EAQ84125.1 - 0.1 12.4 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Sigma54_activat PF00158.21 EAQ84125.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Frataxin_Cyay PF01491.11 EAQ84128.1 - 2.6e-34 117.3 0.0 3.4e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.15 EAQ84129.1 - 8.2e-43 145.5 0.0 1.9e-42 144.3 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain TPR_10 PF13374.1 EAQ84130.1 - 1.8e-92 300.9 0.0 2.1e-12 46.4 0.0 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ84130.1 - 1.5e-76 252.3 0.0 2e-17 62.9 0.0 5.6 2 1 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ84130.1 - 1.5e-28 96.3 1.1 0.0018 17.9 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ84130.1 - 4.2e-19 66.8 0.3 0.3 11.1 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ84130.1 - 2e-17 62.5 0.1 7.2e-05 22.3 0.0 5.3 2 2 2 5 5 5 4 TPR repeat TPR_4 PF07721.9 EAQ84130.1 - 5.2e-16 57.3 0.0 12 6.7 0.0 9.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ84130.1 - 3.4e-15 56.2 0.1 0.0052 17.4 0.0 6.1 4 3 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ84130.1 - 2.1e-14 52.3 0.0 1.1 8.9 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ84130.1 - 4.1e-14 51.8 6.4 3.5 8.5 0.0 9.1 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ84130.1 - 1.4e-13 49.8 1.8 5.7 7.4 0.0 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ84130.1 - 1.9e-10 40.1 0.0 3.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EAQ84130.1 - 1.6e-09 37.9 0.6 0.16 12.3 0.0 6.3 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 EAQ84130.1 - 5.5e-09 35.6 0.0 9.3 6.1 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ84130.1 - 6.9e-09 34.8 0.0 12 5.9 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.15 EAQ84130.1 - 9.5e-08 31.5 2.4 16 5.7 0.0 6.7 6 0 0 6 6 6 0 PPR repeat TPR_5 PF12688.2 EAQ84130.1 - 1e-06 28.7 0.0 2.5 8.1 0.0 5.4 1 1 4 5 5 5 1 Tetratrico peptide repeat TPR_6 PF13174.1 EAQ84130.1 - 1.1e-06 28.7 2.4 24 5.6 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF4074 PF13293.1 EAQ84130.1 - 0.0002 21.4 0.0 1e+02 3.2 0.0 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4074) NACHT PF05729.7 EAQ84130.1 - 0.00054 19.6 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 EAQ84130.1 - 0.0037 16.6 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2664 PF10867.3 EAQ84130.1 - 0.0046 17.5 0.0 54 4.5 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2664) tRNA-synt_1 PF00133.17 EAQ84131.1 - 4.4e-39 133.9 0.0 1.6e-28 99.0 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EAQ84131.1 - 9.1e-19 67.3 0.0 1.3e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EAQ84131.1 - 8.1e-13 48.3 0.3 1.7e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EAQ84131.1 - 4e-09 36.0 0.0 9.5e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ABG_transport PF03806.8 EAQ84132.1 - 0.021 12.8 5.9 0.023 12.7 4.1 1.1 1 0 0 1 1 1 0 AbgT putative transporter family RVP PF00077.15 EAQ84132.1 - 0.13 12.1 1.2 0.17 11.7 0.9 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Sporozoite_P67 PF05642.6 EAQ84132.1 - 0.44 8.3 4.2 0.5 8.1 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-CSL PF05207.8 EAQ84133.1 - 8.8e-25 85.9 0.7 1.1e-24 85.7 0.5 1.1 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 EAQ84133.1 - 0.0027 16.9 1.1 0.0054 16.0 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RING_4 PF14570.1 EAQ84133.1 - 0.059 12.9 0.3 0.087 12.4 0.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EF-hand_4 PF12763.2 EAQ84134.1 - 1.1e-27 95.8 0.0 4.1e-14 52.1 0.0 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EAQ84134.1 - 4.5e-08 33.1 0.1 5.6e-05 23.1 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EAQ84134.1 - 2.6e-05 23.1 0.1 1.3 8.5 0.0 3.8 3 0 0 3 3 3 1 EF hand Macoilin PF09726.4 EAQ84134.1 - 9.9e-05 20.8 16.4 9.9e-05 20.8 11.4 2.3 2 1 0 2 2 1 1 Transmembrane protein EF-hand_8 PF13833.1 EAQ84134.1 - 0.00051 19.5 0.0 0.39 10.3 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EAQ84134.1 - 0.00057 19.5 0.4 0.95 9.5 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain UBA PF00627.26 EAQ84134.1 - 0.002 17.8 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain CENP-F_leu_zip PF10473.4 EAQ84134.1 - 0.0035 17.1 33.5 0.014 15.2 9.9 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 EAQ84134.1 - 0.0065 15.0 20.8 0.013 14.0 14.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) WEMBL PF05701.6 EAQ84134.1 - 0.011 14.2 25.2 0.019 13.4 17.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ADIP PF11559.3 EAQ84134.1 - 0.021 14.7 39.2 0.12 12.2 7.5 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EAQ84134.1 - 0.075 12.6 33.7 0.037 13.6 10.7 2.3 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EAQ84134.1 - 0.17 11.6 39.6 2.4 7.9 18.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EAQ84134.1 - 0.22 10.7 34.6 0.7 9.0 14.0 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EAQ84134.1 - 0.3 10.2 11.4 1.3 8.1 2.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 EAQ84134.1 - 0.5 8.5 19.9 0.89 7.7 13.8 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-Q PF13094.1 EAQ84134.1 - 0.77 9.7 38.4 0.1 12.6 10.3 3.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 EAQ84134.1 - 0.85 8.2 31.3 1.4 7.5 5.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_27 PF13514.1 EAQ84134.1 - 0.93 7.0 26.2 1.4 6.4 18.1 1.1 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 EAQ84134.1 - 0.97 9.1 28.9 1.2 8.8 2.3 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Rab5-bind PF09311.6 EAQ84134.1 - 1.1 9.0 36.0 0.64 9.8 14.8 2.5 1 1 1 2 2 2 0 Rabaptin-like protein MAD PF05557.8 EAQ84134.1 - 1.4 6.8 28.3 2.1 6.3 19.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein COG2 PF06148.6 EAQ84134.1 - 1.5 8.7 15.7 0.044 13.6 2.4 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.3 EAQ84134.1 - 1.5 8.6 37.4 2.2 8.1 3.6 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EAQ84134.1 - 2.2 6.6 25.9 3.9 5.7 17.9 1.3 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EAQ84134.1 - 3.1 7.4 31.8 0.29 10.7 7.8 2.6 1 1 2 3 3 3 0 Mnd1 family DUF2730 PF10805.3 EAQ84134.1 - 3.6 7.3 10.8 1.3 8.7 1.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF724 PF05266.9 EAQ84134.1 - 3.7 7.1 24.1 1.4 8.5 7.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) FUSC PF04632.7 EAQ84134.1 - 4.8 5.5 6.2 8.3 4.7 4.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.6 EAQ84134.1 - 6.1 6.6 36.6 6.1 6.6 11.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.7 EAQ84134.1 - 6.6 6.7 25.9 1.6 8.6 0.3 4.8 4 1 1 5 5 5 0 MbeD/MobD like DUF1664 PF07889.7 EAQ84134.1 - 6.8 6.5 14.3 0.63 9.8 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 EAQ84134.1 - 7.2 6.6 40.0 1.5 8.8 7.2 3.7 1 1 2 3 3 3 0 FlxA-like protein Filament PF00038.16 EAQ84134.1 - 7.7 5.8 33.8 2.7 7.3 9.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.5 EAQ84134.1 - 8.4 6.5 25.6 0.75 9.9 7.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EAQ84134.1 - 9.6 5.1 35.1 3.2 6.7 14.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EAQ84134.1 - 9.7 6.1 15.0 8.8 6.3 0.4 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 EAQ84134.1 - 9.8 5.0 33.0 4.6 6.1 10.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tubulin PF00091.20 EAQ84135.1 - 3.4e-68 229.7 0.0 4.6e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAQ84135.1 - 1.9e-49 166.8 0.1 3.3e-49 166.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EAQ84135.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EAQ84135.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) BTB_2 PF02214.17 EAQ84136.1 - 2.6e-05 24.3 0.1 0.012 15.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DivIVA PF05103.8 EAQ84137.1 - 0.11 12.5 4.1 0.36 10.8 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein Pex14_N PF04695.8 EAQ84137.1 - 4.3 7.3 13.5 5.1 7.1 4.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cyt-b5 PF00173.23 EAQ84139.1 - 1.9e-09 37.2 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CENP-X PF09415.5 EAQ84141.1 - 4.6e-27 93.6 0.2 4.6e-27 93.6 0.2 1.5 2 0 0 2 2 2 1 CENP-S associating Centromere protein X DUF4604 PF15377.1 EAQ84141.1 - 9.2e-05 22.7 0.5 0.00013 22.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) BSP_II PF05432.6 EAQ84141.1 - 0.016 14.5 2.8 0.022 14.0 2.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mito_carr PF00153.22 EAQ84142.1 - 3.5e-66 218.9 7.0 2.3e-23 81.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 EAQ84143.1 - 1.2e-39 134.5 5.8 1.3e-39 134.3 4.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 EAQ84143.1 - 0.0016 17.6 0.2 0.0024 17.1 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.1 EAQ84143.1 - 0.0028 16.9 0.2 0.0044 16.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.7 EAQ84143.1 - 0.0055 16.2 0.1 0.0077 15.7 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.2 EAQ84143.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 EAQ84143.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 EAQ84143.1 - 0.043 13.5 0.2 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 EAQ84143.1 - 0.058 13.0 0.1 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 HTH domain FeoC PF09012.5 EAQ84143.1 - 0.095 12.4 0.3 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_27 PF13463.1 EAQ84143.1 - 0.12 12.7 0.1 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.5 EAQ84143.1 - 0.13 11.8 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ribosomal_S7 PF00177.16 EAQ84144.1 - 3.9e-41 140.0 0.9 5e-41 139.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.19 EAQ84145.1 - 2.8e-10 40.0 0.1 1.1e-07 31.7 0.0 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ84145.1 - 1e-07 32.0 0.0 1.6e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAQ84145.1 - 4.1e-05 23.3 0.0 9.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.1 EAQ84145.1 - 6.9e-05 23.3 0.0 0.078 13.5 0.0 2.8 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ84145.1 - 0.0095 15.6 0.0 0.089 12.5 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EAQ84145.1 - 0.011 15.8 0.0 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ECR1_N PF14382.1 EAQ84145.1 - 0.11 11.8 1.8 0.39 10.0 0.0 2.8 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region adh_short PF00106.20 EAQ84146.1 - 3e-27 95.5 0.0 3.9e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ84146.1 - 1.6e-15 57.5 0.0 2.3e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ84146.1 - 7e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ84146.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ84146.1 - 0.0029 16.5 0.0 0.0078 15.1 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EAQ84146.1 - 0.013 15.2 0.2 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PIGA PF08288.7 EAQ84148.1 - 5.3e-47 158.1 4.1 1.1e-46 157.1 1.0 2.5 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EAQ84148.1 - 4.4e-28 97.8 0.0 6.6e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EAQ84148.1 - 3.9e-19 69.0 1.1 7.8e-19 68.0 0.7 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EAQ84148.1 - 5.3e-17 62.4 0.0 1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EAQ84148.1 - 2.9e-15 56.5 0.0 4.9e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EAQ84148.1 - 1.4e-08 34.7 0.3 2.3e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EAQ84148.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EAQ84148.1 - 0.072 12.5 0.2 0.23 10.8 0.1 2.0 1 1 0 1 1 1 0 Starch synthase catalytic domain DEAD PF00270.24 EAQ84149.1 - 3.4e-32 111.2 0.0 5.3e-15 55.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ84149.1 - 5.9e-21 74.1 0.1 1.2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ84149.1 - 3.5e-07 30.2 0.0 3.5e-07 30.2 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CobT PF06213.7 EAQ84149.1 - 6.9e-05 22.1 5.5 6.9e-05 22.1 3.8 3.3 3 1 1 4 4 4 1 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EAQ84149.1 - 0.0023 16.0 5.6 0.0023 16.0 3.9 3.0 3 0 0 3 3 3 1 CDC45-like protein Flavi_DEAD PF07652.9 EAQ84149.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain SAPS PF04499.10 EAQ84149.1 - 4.6 5.7 10.6 3 6.4 0.7 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TATR PF03430.8 EAQ84149.1 - 4.6 5.7 19.3 2.6 6.5 2.4 2.3 2 0 0 2 2 2 0 Trans-activating transcriptional regulator HSP70 PF00012.15 EAQ84150.1 - 9e-35 119.6 8.6 2.7e-18 65.2 6.8 4.3 3 1 0 3 3 3 2 Hsp70 protein HET PF06985.6 EAQ84151.1 - 1.1e-25 90.4 0.0 1.8e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SlyX PF04102.7 EAQ84152.1 - 0.02 15.2 0.1 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 SlyX DASH_Spc34 PF08657.5 EAQ84152.1 - 0.021 14.4 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 Filament PF00038.16 EAQ84152.1 - 0.023 14.1 1.4 0.03 13.7 0.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein HCR PF07111.7 EAQ84152.1 - 0.025 12.6 1.7 0.032 12.2 1.2 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) IncA PF04156.9 EAQ84152.1 - 0.12 11.9 0.5 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 IncA protein USP8_interact PF08941.5 EAQ84152.1 - 0.15 11.3 0.2 0.2 10.9 0.1 1.1 1 0 0 1 1 1 0 USP8 interacting TMF_DNA_bd PF12329.3 EAQ84152.1 - 0.16 11.8 2.8 0.28 11.0 2.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EAQ84152.1 - 0.19 11.1 2.7 0.47 9.9 1.9 1.6 1 1 0 1 1 1 0 Septum formation initiator MerR-DNA-bind PF09278.6 EAQ84152.1 - 0.25 11.7 1.7 0.44 10.9 1.2 1.4 1 0 0 1 1 1 0 MerR, DNA binding Arginase PF00491.16 EAQ84153.1 - 0.0013 18.0 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family HET PF06985.6 EAQ84154.1 - 8.7e-31 106.9 0.0 1.7e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_11 PF00457.12 EAQ84155.1 - 1.1e-72 243.2 18.9 1.3e-72 242.9 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Surface_antigen PF11054.3 EAQ84155.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen PIF1 PF05970.9 EAQ84157.1 - 4.5e-09 35.7 0.1 8e-09 34.9 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ84157.1 - 2.4e-05 24.0 0.0 6.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ84157.1 - 0.00044 20.3 0.0 0.0017 18.4 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF1996 PF09362.5 EAQ84158.1 - 4e-89 298.2 0.7 5.1e-89 297.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ceramidase PF05875.7 EAQ84159.1 - 1.1e-42 145.9 1.4 1.3e-42 145.8 0.9 1.0 1 0 0 1 1 1 1 Ceramidase Grp1_Fun34_YaaH PF01184.14 EAQ84159.1 - 0.008 15.4 3.5 0.012 14.9 2.4 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Bromodomain PF00439.20 EAQ84160.1 - 2.9e-13 49.5 0.0 6.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DUF465 PF04325.8 EAQ84160.1 - 0.18 11.5 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) APH PF01636.18 EAQ84161.1 - 1.3e-06 28.3 1.8 2.4e-06 27.4 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAQ84161.1 - 0.00014 21.1 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EAQ84161.1 - 0.0003 20.1 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EAQ84161.1 - 0.00095 18.7 0.1 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EAQ84161.1 - 0.16 10.7 0.2 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase XPG_I_2 PF12813.2 EAQ84163.1 - 0.027 13.9 0.1 0.048 13.1 0.1 1.3 1 1 0 1 1 1 0 XPG domain containing HSP70 PF00012.15 EAQ84164.1 - 1.4e-07 29.8 0.0 8.2e-05 20.7 0.0 2.9 2 1 0 2 2 2 2 Hsp70 protein UPF0081 PF03652.10 EAQ84164.1 - 0.058 13.5 0.0 8.3 6.5 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0081) BcrAD_BadFG PF01869.15 EAQ84164.1 - 0.17 11.1 0.0 0.47 9.7 0.0 1.8 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1693 PF07984.7 EAQ84164.1 - 0.23 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1693) Tropomyosin PF00261.15 EAQ84165.1 - 0.00019 20.6 4.2 0.00034 19.7 2.9 1.4 1 0 0 1 1 1 1 Tropomyosin AAA_13 PF13166.1 EAQ84165.1 - 0.0058 15.1 0.5 0.0081 14.6 0.3 1.1 1 0 0 1 1 1 1 AAA domain Leu_zip PF15294.1 EAQ84165.1 - 0.0084 15.2 2.3 0.014 14.5 1.6 1.3 1 0 0 1 1 1 1 Leucine zipper CENP-F_leu_zip PF10473.4 EAQ84165.1 - 0.013 15.3 4.6 0.028 14.2 3.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 EAQ84165.1 - 0.016 14.9 3.6 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mnd1 PF03962.10 EAQ84165.1 - 0.05 13.2 2.3 0.094 12.3 1.6 1.4 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 EAQ84165.1 - 0.068 12.2 5.3 0.11 11.5 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EAQ84165.1 - 0.36 8.6 0.4 0.47 8.2 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EAQ84165.1 - 0.41 10.1 4.4 6 6.3 3.0 2.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EAQ84165.1 - 0.68 9.6 8.0 0.43 10.3 4.0 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 EAQ84165.1 - 1 8.7 9.9 3.2 7.0 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF972 PF06156.8 EAQ84165.1 - 1 9.7 5.8 14 6.0 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FUSC PF04632.7 EAQ84165.1 - 3.1 6.1 4.0 5.9 5.2 2.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.1 EAQ84165.1 - 3.5 6.5 5.3 5.6 5.8 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2514 PF10721.4 EAQ84165.1 - 4.3 7.0 9.7 7.4 6.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) IBR PF01485.16 EAQ84166.1 - 6.5e-24 83.5 28.2 5.2e-13 48.6 1.4 3.4 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EAQ84166.1 - 0.0061 16.1 25.0 0.25 11.0 5.2 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Baculo_E56 PF04639.7 EAQ84166.1 - 0.022 13.4 0.5 0.032 12.8 0.3 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope C1_4 PF07975.7 EAQ84166.1 - 5.1 7.1 21.9 0.073 13.0 4.6 3.3 3 0 0 3 3 3 0 TFIIH C1-like domain His_Phos_1 PF00300.17 EAQ84167.1 - 4e-21 75.7 0.0 4e-20 72.5 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EAQ84167.1 - 0.2 10.9 0.1 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) RasGEF PF00617.14 EAQ84168.1 - 1.1e-51 175.2 0.0 2.2e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain DNA_binding_1 PF01035.15 EAQ84168.1 - 9.7e-22 76.5 0.1 2.1e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RasGEF_N PF00618.15 EAQ84168.1 - 2.8e-16 59.5 0.0 7.1e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EAQ84168.1 - 2.8e-06 26.7 0.0 5.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ84168.1 - 2.8e-05 23.3 0.0 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EAQ84168.1 - 0.0074 15.7 0.0 0.061 12.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain MFS_1 PF07690.11 EAQ84170.1 - 7.5e-17 61.0 31.5 7.5e-17 61.0 21.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EAQ84170.1 - 7.8e-11 41.7 3.3 7.8e-11 41.7 2.3 2.8 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 AcetylCoA_hyd_C PF13336.1 EAQ84171.1 - 8.8e-38 129.4 0.0 1.3e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EAQ84171.1 - 4.9e-33 114.5 0.0 1.5e-31 109.6 0.0 2.2 1 1 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CBM_1 PF00734.13 EAQ84172.1 - 2.3e-09 36.7 13.2 2.3e-09 36.7 9.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.11 EAQ84173.1 - 2e-22 79.4 54.5 6e-20 71.2 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ84173.1 - 4e-17 61.9 27.6 1.5e-16 60.0 19.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.4 EAQ84173.1 - 3.8 7.7 8.3 0.25 11.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) Sulfotransfer_3 PF13469.1 EAQ84174.1 - 0.009 16.9 7.1 0.025 15.5 4.9 1.8 1 1 0 1 1 1 1 Sulfotransferase family Epimerase PF01370.16 EAQ84175.1 - 6e-14 52.0 0.0 7.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ84175.1 - 1.5e-05 24.0 0.2 0.00031 19.7 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EAQ84175.1 - 0.00046 18.9 0.0 0.036 12.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAQ84175.1 - 0.0036 17.2 0.0 0.0084 16.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAQ84175.1 - 0.061 12.2 0.0 6.4 5.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAQ84175.1 - 0.2 10.4 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RVT_1 PF00078.22 EAQ84176.1 - 1.2e-22 80.3 0.0 2.3e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84176.1 - 3.9e-20 71.6 0.1 5.3e-19 67.9 0.2 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84176.1 - 6e-07 29.6 0.2 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ84176.1 - 0.0052 17.1 4.1 0.07 13.5 0.7 2.9 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ84176.1 - 0.06 12.3 1.9 0.11 11.4 1.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ84176.1 - 0.33 11.0 5.9 0.1 12.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) TPR_12 PF13424.1 EAQ84177.1 - 5.6e-22 77.4 0.8 3.3e-09 36.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Patatin PF01734.17 EAQ84177.1 - 5e-18 65.7 0.0 1.1e-17 64.6 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 EAQ84177.1 - 2.6e-14 52.5 11.3 9e-06 25.4 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ84177.1 - 6.6e-07 29.8 4.1 0.48 11.1 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ84177.1 - 1.9e-06 26.9 0.0 3.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EAQ84177.1 - 0.00022 20.7 0.4 0.18 11.4 0.0 3.2 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAQ84177.1 - 0.054 13.4 6.5 6.1 7.0 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2346 PF09803.4 EAQ84177.1 - 0.09 12.6 0.0 7.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) TPR_16 PF13432.1 EAQ84180.1 - 0.079 13.6 0.7 0.14 12.8 0.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat RVT_1 PF00078.22 EAQ84182.1 - 1.8e-38 132.0 0.0 2.7e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84182.1 - 7.9e-13 48.0 0.0 1.9e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84182.1 - 5.6e-08 33.0 0.1 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-NADH-PPase PF09297.6 EAQ84182.1 - 3.5 7.2 10.1 12 5.4 1.2 3.0 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ank_2 PF12796.2 EAQ84183.1 - 2.5e-92 303.3 10.8 3.7e-22 78.4 0.9 6.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84183.1 - 5.2e-84 272.1 27.9 2.8e-07 30.0 0.0 14.3 13 1 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.1 EAQ84183.1 - 8.6e-72 235.5 26.0 4.3e-10 39.5 0.0 11.6 2 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84183.1 - 1.2e-68 220.1 14.3 1.2e-05 25.0 0.0 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 EAQ84183.1 - 2.7e-65 215.6 11.8 2.7e-11 43.6 0.0 9.0 4 2 5 9 9 9 9 Ankyrin repeats (many copies) NEL PF14496.1 EAQ84184.1 - 0.07 12.4 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting HET PF06985.6 EAQ84185.1 - 1.7e-27 96.2 0.0 3.7e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EAQ84186.1 - 0.0014 18.7 0.0 0.0037 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EAQ84186.1 - 0.016 15.0 0.0 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 Torsin FtsK_SpoIIIE PF01580.13 EAQ84186.1 - 0.076 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4475 PF14753.1 EAQ84187.1 - 0.032 13.7 2.9 0.035 13.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) AFOR_N PF02730.10 EAQ84187.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Pkinase PF00069.20 EAQ84188.1 - 3.9e-08 32.7 0.0 7.5e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TauD PF02668.11 EAQ84189.1 - 2.9e-25 89.4 0.0 6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EAQ84189.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.13 EAQ84189.1 - 0.29 11.1 6.4 0.57 10.1 4.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EAQ84190.1 - 0.066 12.3 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PI3_PI4_kinase PF00454.22 EAQ84190.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase CbtB PF09489.5 EAQ84190.1 - 2.2 8.2 4.0 22 5.0 0.1 2.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF1992 PF09350.5 EAQ84191.1 - 1.7e-25 88.6 0.4 3.4e-25 87.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Acetyltransf_10 PF13673.1 EAQ84191.1 - 3.2e-05 24.0 0.0 8.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ84191.1 - 0.0087 16.0 0.0 0.027 14.4 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ84191.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ornatin PF02088.10 EAQ84192.1 - 1.1 8.8 5.3 0.28 10.7 1.3 1.8 2 0 0 2 2 2 0 Ornatin PMT_2 PF13231.1 EAQ84193.1 - 0.034 14.0 6.8 0.17 11.7 4.7 2.1 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase MgsA_C PF12002.3 EAQ84195.1 - 6.4e-60 201.6 0.0 1.2e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EAQ84195.1 - 2.2e-12 47.3 0.0 4.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAQ84195.1 - 2.6e-09 36.4 0.0 1.1e-08 34.4 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAQ84195.1 - 1.5e-05 25.1 0.2 6.2e-05 23.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EAQ84195.1 - 3.9e-05 23.2 0.1 0.0022 17.5 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EAQ84195.1 - 9.9e-05 22.3 3.3 0.0053 16.7 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EAQ84195.1 - 0.00015 21.4 0.2 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EAQ84195.1 - 0.00059 19.0 0.1 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAQ84195.1 - 0.00067 20.4 0.0 0.0016 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAQ84195.1 - 0.00074 19.2 0.2 0.024 14.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EAQ84195.1 - 0.00076 18.3 0.0 0.0052 15.5 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EAQ84195.1 - 0.0021 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SKI PF01202.17 EAQ84195.1 - 0.0042 16.9 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase AAA_14 PF13173.1 EAQ84195.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EAQ84195.1 - 0.021 14.4 0.0 0.13 11.8 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EAQ84195.1 - 0.036 14.0 0.1 0.084 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ84195.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EAQ84195.1 - 0.077 12.8 1.4 5.6 6.7 0.0 2.5 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EAQ84195.1 - 0.079 13.2 0.3 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EAQ84195.1 - 0.22 10.9 2.5 6.8 6.0 0.1 3.0 2 2 2 4 4 4 0 AAA-like domain Fe-S_biosyn PF01521.15 EAQ84196.1 - 9.3e-14 51.3 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 EAQ84196.1 - 3.6 6.8 24.2 4.8 6.4 16.8 1.1 1 0 0 1 1 1 0 Vta1 like CMV_1a PF12467.3 EAQ84196.1 - 5.1 7.4 7.8 9.6 6.5 5.4 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF1741 PF08427.5 EAQ84197.1 - 4e-88 294.8 0.0 8.4e-88 293.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) CLN3 PF02487.12 EAQ84201.1 - 7.9e-102 341.0 23.8 8.6e-94 314.5 11.0 2.9 1 1 1 2 2 2 2 CLN3 protein Peptidase_M28 PF04389.12 EAQ84202.1 - 3.1e-31 108.4 0.0 5.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAQ84202.1 - 4.8e-19 67.9 0.3 8.9e-19 67.0 0.2 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EAQ84202.1 - 4.5e-07 29.5 0.0 7.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M13_N PF05649.8 EAQ84203.1 - 1.2e-57 195.7 0.0 1.8e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EAQ84203.1 - 2.5e-54 183.5 0.0 4.7e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Dimer_Tnp_hAT PF05699.9 EAQ84204.1 - 1.6e-12 46.8 0.1 3.6e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 EAQ84204.1 - 1.5e-09 37.3 0.0 2.2e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84204.1 - 0.00037 19.6 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.16 EAQ84205.1 - 1.3e-46 159.4 0.1 3.8e-46 157.8 0.0 1.7 1 1 1 2 2 2 1 Amidase WW PF00397.21 EAQ84206.1 - 0.082 12.7 0.5 0.2 11.5 0.3 1.7 1 1 1 2 2 2 0 WW domain TPR_12 PF13424.1 EAQ84207.1 - 3.3e-14 52.5 4.4 3.9e-08 33.1 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ84207.1 - 3.2e-13 49.1 0.0 8.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EAQ84207.1 - 5.6e-11 41.9 7.8 7.6e-06 25.4 2.9 3.9 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAQ84207.1 - 1e-09 37.5 8.6 0.0021 17.8 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ84207.1 - 3.9e-06 26.2 8.2 0.032 13.8 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ84207.1 - 1.2e-05 25.4 0.7 4.6 8.1 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.1 EAQ84207.1 - 2.1e-05 24.6 0.1 0.00017 21.6 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain TPR_10 PF13374.1 EAQ84207.1 - 3.5e-05 23.5 5.9 0.00081 19.2 0.4 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ84207.1 - 0.0002 20.9 3.3 0.18 11.7 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ84207.1 - 0.00046 19.7 6.8 0.077 12.8 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat HTH_OrfB_IS605 PF12323.3 EAQ84207.1 - 0.0011 18.2 1.0 0.0076 15.5 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_22 PF13401.1 EAQ84207.1 - 0.0012 18.9 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EAQ84207.1 - 0.0033 18.0 1.9 0.98 10.1 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ84207.1 - 0.0044 17.1 0.1 0.09 12.9 0.0 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EAQ84207.1 - 0.0093 16.2 0.6 0.24 11.7 0.2 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 EAQ84207.1 - 0.049 13.4 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) KaiC PF06745.8 EAQ84207.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC GCR1_C PF12550.3 EAQ84209.1 - 4.2e-18 64.9 0.0 1.9e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HalX PF08663.5 EAQ84209.1 - 1 9.3 6.4 0.19 11.7 1.6 2.0 2 0 0 2 2 2 0 HalX domain RVT_1 PF00078.22 EAQ84210.1 - 1.1e-12 47.8 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ84210.1 - 1.5e-11 43.8 5.5 3.2e-11 42.7 3.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EAQ84210.1 - 2.7e-11 43.6 0.0 7.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 EAQ84210.1 - 0.029 14.8 0.0 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease CAF-1_p150 PF11600.3 EAQ84210.1 - 2 7.7 20.8 4 6.7 14.4 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DNA_ligase_A_M PF01068.16 EAQ84211.1 - 0.12 11.7 0.0 2.9 7.2 0.0 2.0 1 1 1 2 2 2 0 ATP dependent DNA ligase domain Rxt3 PF08642.5 EAQ84212.1 - 1.7e-28 99.1 0.0 4e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EAQ84212.1 - 7.2e-07 29.1 0.0 0.00023 21.0 0.0 2.4 2 0 0 2 2 2 2 LCCL domain Sugar_tr PF00083.19 EAQ84213.1 - 2.1e-118 395.8 21.3 2.3e-118 395.6 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84213.1 - 4e-20 71.8 36.4 5.7e-15 54.8 7.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Bromodomain PF00439.20 EAQ84216.1 - 1.5e-43 146.5 0.2 1.4e-23 82.5 0.1 3.0 3 0 0 3 3 3 2 Bromodomain DUF3489 PF11994.3 EAQ84216.1 - 0.029 14.2 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Utp12 PF04003.7 EAQ84217.1 - 5.3e-25 87.4 0.0 8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nop14 PF04147.7 EAQ84217.1 - 3.8 5.3 28.9 0.23 9.3 14.5 2.0 2 0 0 2 2 2 0 Nop14-like family TPR_12 PF13424.1 EAQ84219.1 - 7.3e-12 45.0 0.4 1.8e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ84219.1 - 4.2e-06 26.2 0.8 2 8.5 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ84219.1 - 3.1e-05 23.4 1.9 0.15 11.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ84219.1 - 0.0011 18.5 0.7 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EAQ84219.1 - 0.0082 15.7 1.7 2.1 8.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ84219.1 - 0.063 13.6 0.1 4.8 7.5 0.0 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ84219.1 - 0.074 12.8 0.1 12 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ84219.1 - 0.13 12.9 1.1 6.2 7.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ84219.1 - 0.15 12.7 0.1 9.6 7.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 EAQ84222.1 - 1.3e-14 54.0 0.3 1.7e-06 27.3 0.0 3.4 4 0 0 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.1 EAQ84222.1 - 0.00018 21.4 0.0 0.00056 19.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ84222.1 - 0.0038 16.1 0.0 0.065 12.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ84222.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ84222.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EAQ84222.1 - 0.032 14.2 0.0 0.12 12.4 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ84222.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding MYEOV2 PF15004.1 EAQ84222.1 - 0.058 13.9 1.6 0.093 13.2 0.2 2.1 2 0 0 2 2 2 0 Myeloma-overexpressed-like NAD_Gly3P_dh_N PF01210.18 EAQ84222.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Melibiase PF02065.13 EAQ84223.1 - 2.6e-18 65.9 0.4 1.6e-16 60.0 0.3 2.3 1 1 0 1 1 1 1 Melibiase Aconitase PF00330.15 EAQ84224.1 - 4.9e-63 213.2 0.1 7e-42 143.4 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAQ84224.1 - 1.5e-25 89.8 0.0 2.9e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Pkinase PF00069.20 EAQ84225.1 - 6.8e-33 113.9 0.0 1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84225.1 - 1.8e-14 53.4 0.0 2.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ84225.1 - 0.036 13.7 0.1 0.17 11.5 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAQ84225.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Sec8_exocyst PF04048.9 EAQ84225.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Albumin_I PF08027.6 EAQ84226.1 - 0.049 13.3 4.3 0.076 12.7 2.9 1.3 1 1 0 1 1 1 0 Albumin I Lactonase PF10282.4 EAQ84227.1 - 9.4e-19 67.6 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller C-C_Bond_Lyase PF15617.1 EAQ84227.1 - 0.069 11.9 0.1 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold MFS_1 PF07690.11 EAQ84228.1 - 3.5e-31 108.2 28.5 8.2e-16 57.6 6.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ84228.1 - 0.00027 20.6 2.4 0.0028 17.4 0.1 2.8 3 0 0 3 3 3 1 MFS_1 like family Sugar_tr PF00083.19 EAQ84228.1 - 0.00032 19.3 19.4 0.011 14.3 13.4 3.3 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EAQ84228.1 - 0.0062 14.6 7.2 1.4 6.8 0.1 3.8 4 1 0 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family PRKCSH PF07915.8 EAQ84231.1 - 2.6e-19 69.7 0.0 2.6e-19 69.7 0.0 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Retinal PF15449.1 EAQ84234.1 - 0.25 8.9 21.8 0.28 8.7 15.1 1.0 1 0 0 1 1 1 0 Retinal protein PAP1 PF08601.5 EAQ84234.1 - 1.5 8.4 11.1 1.7 8.2 7.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 MAP65_ASE1 PF03999.7 EAQ84234.1 - 2.2 6.7 10.7 2.7 6.4 7.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SOG2 PF10428.4 EAQ84234.1 - 5.3 5.5 11.2 5.7 5.4 7.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein His_Phos_1 PF00300.17 EAQ84235.1 - 6.3e-17 62.1 0.0 7.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Macro PF01661.16 EAQ84236.1 - 0.023 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Macro domain RVT_1 PF00078.22 EAQ84238.1 - 1.6e-33 115.8 0.0 2.5e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84238.1 - 1e-13 50.9 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84238.1 - 9.1e-10 38.8 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PIF1 PF05970.9 EAQ84239.1 - 2.5e-32 112.2 0.0 6.4e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ84239.1 - 2.5e-06 27.2 0.0 8.4e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ84239.1 - 0.00024 20.8 0.1 0.00088 18.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ84239.1 - 0.0011 16.8 0.0 0.024 12.3 0.0 2.1 2 0 0 2 2 2 1 Helicase F-box-like PF12937.2 EAQ84239.1 - 0.0035 17.0 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like UvrD_C_2 PF13538.1 EAQ84239.1 - 0.011 15.8 0.0 0.051 13.7 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Torsin PF06309.6 EAQ84239.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Torsin PTP_N PF12453.3 EAQ84240.1 - 0.2 11.2 0.8 0.2 11.2 0.6 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal MFS_1 PF07690.11 EAQ84241.1 - 9.7e-33 113.3 52.5 9.7e-33 113.3 36.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ84241.1 - 3.5e-06 25.8 16.4 3.5e-06 25.8 11.4 3.8 3 1 0 4 4 4 2 Sugar (and other) transporter Methyltransf_2 PF00891.13 EAQ84242.1 - 4.1e-25 88.3 0.0 8.9e-25 87.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAQ84242.1 - 7.4e-07 29.7 0.0 2.3e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ84242.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EAQ84242.1 - 0.0064 16.8 0.0 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ84242.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EAQ84242.1 - 0.015 14.9 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EAQ84242.1 - 0.054 12.5 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EAQ84242.1 - 0.12 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ketoacyl-synt PF00109.21 EAQ84243.1 - 4.7e-66 222.8 0.0 1.2e-65 221.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EAQ84243.1 - 6.2e-62 209.4 2.1 1.4e-61 208.2 1.4 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EAQ84243.1 - 8.8e-56 189.5 0.3 2.2e-55 188.2 0.2 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EAQ84243.1 - 1.3e-47 161.8 1.5 2.5e-47 160.8 0.1 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EAQ84243.1 - 5.6e-36 123.9 0.1 5.6e-36 123.9 0.1 3.3 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ84243.1 - 5.9e-31 106.7 0.0 2.7e-30 104.6 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EAQ84243.1 - 2.5e-16 59.9 0.0 8.4e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ84243.1 - 9e-12 44.9 0.0 6e-11 42.3 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ84243.1 - 6e-11 42.9 0.1 2.2e-09 37.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84243.1 - 9.1e-09 35.6 0.0 6.7e-08 32.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ84243.1 - 4.2e-08 32.9 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EAQ84243.1 - 2.5e-05 23.9 0.2 7.1e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EAQ84243.1 - 0.00084 18.9 0.3 0.0027 17.3 0.2 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.21 EAQ84243.1 - 0.0014 18.1 0.5 0.014 14.9 0.2 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EAQ84243.1 - 0.0023 16.9 0.1 0.0078 15.2 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EAQ84243.1 - 0.045 12.8 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 EAQ84243.1 - 0.28 9.8 0.0 0.5 9.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_4 PF01565.18 EAQ84244.1 - 4.5e-20 71.5 9.2 8e-14 51.2 0.0 3.1 3 1 1 4 4 4 2 FAD binding domain BBE PF08031.7 EAQ84244.1 - 0.00091 19.0 0.5 0.0021 17.9 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EAQ84245.1 - 4.4e-09 35.3 0.1 1.9e-07 30.0 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 EAQ84246.1 - 3.3e-07 29.4 0.2 5.7e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EAQ84248.1 - 1.5e-09 38.0 0.6 3e-09 37.0 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ84248.1 - 6e-06 26.2 0.4 8.1e-06 25.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ84248.1 - 7.8e-05 22.4 0.1 0.00018 21.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EAQ84248.1 - 0.0021 18.1 0.1 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_12 PF13087.1 EAQ84249.1 - 9.4e-41 139.3 0.0 2.7e-40 137.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAQ84249.1 - 9.1e-32 110.5 9.2 1.3e-28 100.2 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 EAQ84249.1 - 4.7e-26 91.5 0.0 3.3e-07 30.5 0.0 6.3 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EAQ84249.1 - 4.3e-15 55.2 0.3 2.7e-10 39.8 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EAQ84249.1 - 5.8e-10 39.0 7.6 1.2e-06 28.2 0.0 4.9 4 2 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EAQ84249.1 - 9.9e-07 28.9 7.5 2.1 8.4 0.0 6.5 6 1 0 6 6 5 2 AAA domain AAA_17 PF13207.1 EAQ84249.1 - 1.1e-05 26.2 3.9 0.18 12.6 0.0 4.2 4 0 0 4 4 3 2 AAA domain DUF2075 PF09848.4 EAQ84249.1 - 1.2e-05 24.4 0.5 0.073 12.0 0.0 4.9 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EAQ84249.1 - 4.6e-05 22.9 0.0 0.26 10.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 EAQ84249.1 - 0.00027 20.6 0.1 0.8 9.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EAQ84249.1 - 0.00082 18.8 0.1 0.11 11.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EAQ84249.1 - 0.0019 17.6 5.7 0.99 8.7 0.0 4.8 4 1 0 4 4 4 1 AAA-like domain RNA_helicase PF00910.17 EAQ84249.1 - 0.002 18.2 0.0 0.9 9.7 0.0 3.2 3 0 0 3 3 2 1 RNA helicase UvrD_C_2 PF13538.1 EAQ84249.1 - 0.0024 17.9 0.1 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Torsin PF06309.6 EAQ84249.1 - 0.0049 16.7 0.0 0.53 10.1 0.0 2.8 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.1 EAQ84249.1 - 0.02 14.7 10.0 2.2 8.1 0.1 4.8 5 0 0 5 5 4 0 AAA domain Mg_chelatase PF01078.16 EAQ84249.1 - 0.026 13.6 0.3 7.4 5.6 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAQ84249.1 - 2.2 8.6 9.7 9 6.6 0.1 4.1 4 0 0 4 4 3 0 AAA domain Herpes_gE PF02480.11 EAQ84250.1 - 0.12 10.6 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amino_oxidase PF01593.19 EAQ84251.1 - 1.1e-18 67.5 0.2 4.4e-15 55.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ84251.1 - 0.00035 20.5 0.0 0.00086 19.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPP_enzyme_N PF02776.13 EAQ84253.1 - 2.5e-36 124.7 0.0 5.7e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAQ84253.1 - 1.9e-10 40.6 0.2 1.1e-08 34.9 0.1 2.3 1 1 1 2 2 2 2 Thiamine pyrophosphate enzyme, central domain RVT_1 PF00078.22 EAQ84254.1 - 1.6e-32 112.6 0.0 3.5e-32 111.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EAQ84254.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 RNase H SET PF00856.23 EAQ84255.1 - 1.2e-08 35.4 0.0 5.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 SET domain HeLo PF14479.1 EAQ84256.1 - 4.1e-44 150.8 0.0 6e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 EAQ84256.1 - 4.9e-11 42.5 0.1 1.9e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ84256.1 - 0.00044 20.2 0.0 0.0019 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ84256.1 - 0.0013 18.8 0.0 0.0046 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAQ84256.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EAQ84256.1 - 0.0036 17.4 0.1 0.015 15.4 0.1 2.0 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.17 EAQ84256.1 - 0.016 14.0 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EAQ84256.1 - 0.024 14.3 0.0 0.066 12.8 0.0 1.8 2 1 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EAQ84256.1 - 0.032 14.5 0.1 0.07 13.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EAQ84256.1 - 0.12 12.2 0.1 0.92 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EAQ84256.1 - 0.24 10.3 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Kdo PF06293.9 EAQ84257.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PBCV_basic_adap PF08789.5 EAQ84258.1 - 0.014 15.0 5.0 1 9.0 0.2 2.6 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain Excalibur PF05901.6 EAQ84258.1 - 0.52 10.7 0.1 0.52 10.7 0.1 2.4 2 0 0 2 2 2 0 Excalibur calcium-binding domain DUF2207 PF09972.4 EAQ84258.1 - 1.1 7.7 4.5 2.1 6.8 3.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF566 PF04484.7 EAQ84258.1 - 1.9 7.9 5.9 2.7 7.4 4.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1814 PF08843.6 EAQ84261.1 - 0.0055 16.5 0.6 0.047 13.4 0.4 2.1 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) MFS_1 PF07690.11 EAQ84263.1 - 3.4e-35 121.4 30.0 4.5e-35 121.0 20.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2142 PF09913.4 EAQ84263.1 - 0.00026 19.7 13.5 0.00035 19.3 3.1 3.3 2 1 1 3 3 3 3 Predicted membrane protein (DUF2142) Dimer_Tnp_hAT PF05699.9 EAQ84264.1 - 4.4e-14 51.8 0.0 8.6e-13 47.7 0.0 2.6 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 EAQ84264.1 - 0.039 13.7 0.1 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger Dimer_Tnp_hAT PF05699.9 EAQ84265.1 - 2.3e-16 59.1 0.1 3.9e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2 PF00096.21 EAQ84265.1 - 0.19 12.1 0.5 1.6 9.2 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Asp PF00026.18 EAQ84266.1 - 6.7e-50 170.1 0.0 6.7e-50 170.1 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TFIIF_alpha PF05793.7 EAQ84266.1 - 0.72 8.1 9.9 1.2 7.4 6.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLD3 PF08639.5 EAQ84266.1 - 4.1 5.9 17.1 5.9 5.4 11.9 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Rep_fac_C PF08542.6 EAQ84267.1 - 1e-18 67.0 0.3 3e-18 65.5 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EAQ84267.1 - 6.2e-16 58.8 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAQ84267.1 - 6.9e-14 51.8 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EAQ84267.1 - 5.9e-09 35.1 0.0 3.5e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EAQ84267.1 - 2e-07 31.2 0.2 9.9e-07 28.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ84267.1 - 3.3e-07 30.4 0.1 5.6e-05 23.1 0.0 3.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EAQ84267.1 - 2.7e-06 27.0 0.0 6.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 EAQ84267.1 - 5.6e-06 25.9 0.4 0.0015 18.1 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAQ84267.1 - 9.7e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAQ84267.1 - 1.7e-05 24.5 0.1 0.00016 21.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 EAQ84267.1 - 2.1e-05 24.2 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAQ84267.1 - 3.6e-05 22.9 0.1 0.00023 20.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EAQ84267.1 - 8.4e-05 21.4 0.0 0.3 9.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 EAQ84267.1 - 8.5e-05 22.3 0.2 0.00027 20.6 0.1 1.9 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EAQ84267.1 - 8.5e-05 22.1 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 EAQ84267.1 - 8.5e-05 21.5 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EAQ84267.1 - 0.00032 20.3 0.0 0.00067 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EAQ84267.1 - 0.00057 19.3 0.1 0.0015 17.9 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain PhoH PF02562.11 EAQ84267.1 - 0.00091 18.5 0.4 0.95 8.6 0.0 2.8 2 1 0 3 3 3 2 PhoH-like protein DUF2075 PF09848.4 EAQ84267.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EAQ84267.1 - 0.0049 16.8 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ84267.1 - 0.0071 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ84267.1 - 0.0094 15.3 0.0 0.035 13.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ84267.1 - 0.014 15.1 0.0 0.059 13.0 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase DEAD PF00270.24 EAQ84267.1 - 0.015 14.8 0.2 0.25 10.7 0.0 2.4 2 1 1 3 3 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EAQ84267.1 - 0.028 15.2 0.0 0.079 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EAQ84267.1 - 0.029 13.5 0.2 0.18 10.9 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EAQ84267.1 - 0.03 13.7 0.1 3.5 6.9 0.0 2.5 1 1 1 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EAQ84267.1 - 0.038 13.4 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.10 EAQ84267.1 - 0.043 13.6 0.0 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RPAP3_C PF13877.1 EAQ84267.1 - 0.046 13.6 0.2 3.4 7.6 0.0 2.9 2 1 0 2 2 1 0 Potential Monad-binding region of RPAP3 RNA_helicase PF00910.17 EAQ84267.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EAQ84267.1 - 0.067 11.9 0.0 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 EAQ84267.1 - 0.07 12.5 0.0 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family TK PF00265.13 EAQ84267.1 - 0.097 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase VTC PF09359.5 EAQ84267.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.3 1 1 0 1 1 1 0 VTC domain UDPGT PF00201.13 EAQ84268.1 - 1.6e-12 46.7 0.0 3.5e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_4 PF13579.1 EAQ84268.1 - 0.031 14.4 0.0 0.09 12.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_28 PF03033.15 EAQ84268.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain adh_short PF00106.20 EAQ84269.1 - 5.7e-19 68.6 0.3 8.8e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ84269.1 - 6e-07 29.2 0.2 1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ84269.1 - 0.00055 19.4 0.1 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ84269.1 - 0.049 12.5 0.0 0.11 11.3 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Microtub_assoc PF07989.6 EAQ84270.1 - 0.00034 20.3 2.4 0.00076 19.2 1.7 1.6 1 1 0 1 1 1 1 Microtubule associated DUF1978 PF09321.5 EAQ84270.1 - 0.52 9.7 7.3 0.82 9.0 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) IncA PF04156.9 EAQ84270.1 - 2.6 7.5 8.8 4.7 6.7 6.1 1.3 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 EAQ84270.1 - 6.8 6.7 11.9 3.5 7.6 0.3 3.2 2 1 1 3 3 3 0 bZIP transcription factor Glyco_hydro_47 PF01532.15 EAQ84271.1 - 4.1e-132 441.0 0.0 1.4e-127 426.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Asp PF00026.18 EAQ84272.1 - 0.0061 15.8 0.3 0.012 14.8 0.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 EAQ84272.1 - 0.0066 16.0 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 EAQ84272.1 - 0.0085 15.3 2.8 0.019 14.2 2.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD99L2 PF12301.3 EAQ84272.1 - 0.17 11.5 3.7 0.34 10.5 2.6 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF2680 PF10925.3 EAQ84273.1 - 0.045 13.6 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF829 PF05705.9 EAQ84276.1 - 4.6e-33 114.9 0.0 6.7e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Prd1-P2 PF09214.6 EAQ84276.1 - 2.8 6.4 4.1 4.3 5.7 2.8 1.3 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 KH_1 PF00013.24 EAQ84277.1 - 1.2e-27 95.3 4.4 1.6e-15 56.4 0.8 3.4 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 EAQ84277.1 - 1.3e-20 72.5 8.8 3.2e-11 42.6 1.1 3.2 3 0 0 3 3 3 2 KH domain KH_2 PF07650.12 EAQ84277.1 - 9.2e-08 31.5 0.3 0.014 14.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EAQ84277.1 - 1.8e-06 27.4 0.2 0.068 12.8 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 EAQ84277.1 - 0.0041 16.8 0.2 0.28 11.0 0.0 2.4 2 0 0 2 2 2 1 NusA-like KH domain Asp PF00026.18 EAQ84278.1 - 1.5e-45 155.8 0.9 2.3e-45 155.2 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EAQ84278.1 - 3.5e-07 30.6 0.1 0.7 10.4 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 EAQ84278.1 - 6.7e-07 28.9 0.1 2.8e-06 26.9 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EAQ84278.1 - 0.0035 17.1 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EAQ84278.1 - 0.12 12.2 0.0 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 Retroviral aspartyl protease DEAD PF00270.24 EAQ84279.1 - 1.8e-43 147.9 0.0 5.6e-43 146.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EAQ84279.1 - 7.9e-21 73.3 1.5 1.2e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EAQ84279.1 - 9.3e-21 73.4 0.0 3.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EAQ84279.1 - 0.0018 17.3 1.2 0.64 9.0 0.0 2.5 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.9 EAQ84279.1 - 0.088 12.0 0.1 0.52 9.5 0.1 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain Hce2 PF14856.1 EAQ84280.1 - 0.0057 16.5 0.4 0.009 15.8 0.3 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor 6PF2K PF01591.13 EAQ84281.1 - 1.6e-78 262.8 0.1 2.2e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EAQ84281.1 - 2.6e-31 108.8 0.0 5.5e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EAQ84281.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EAQ84281.1 - 0.0003 20.0 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EAQ84281.1 - 0.0004 21.1 0.3 0.0063 17.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAQ84281.1 - 0.013 14.6 0.0 0.054 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 EAQ84281.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase YbaJ PF10757.4 EAQ84282.1 - 0.019 15.0 0.2 0.91 9.6 0.0 2.9 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ Baculo_PEP_C PF04513.7 EAQ84282.1 - 0.12 12.2 15.8 0.29 10.9 1.1 4.2 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trp_syntA PF00290.15 EAQ84283.1 - 2.8e-92 307.8 0.3 5.7e-92 306.9 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EAQ84283.1 - 5e-45 154.0 1.0 1.1e-44 152.9 0.7 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 EAQ84283.1 - 0.0015 17.8 0.2 0.33 10.1 0.1 2.4 2 0 0 2 2 2 2 PcrB family Ribosomal_L28 PF00830.14 EAQ84284.1 - 5e-21 74.3 1.7 7.1e-21 73.8 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Aminotran_1_2 PF00155.16 EAQ84286.1 - 7.8e-35 120.4 0.0 9.3e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_N PF08240.7 EAQ84288.1 - 2.3e-23 82.0 6.0 4.1e-23 81.2 4.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ84288.1 - 9.7e-21 73.6 0.0 1.5e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ84288.1 - 1e-06 29.6 0.0 2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EAQ84288.1 - 0.00082 19.4 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EAQ84288.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EAQ84288.1 - 0.0098 15.7 0.1 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EAQ84288.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Rod_cone_degen PF15201.1 EAQ84290.1 - 9 6.2 8.4 1.6 8.6 0.3 3.2 3 1 1 4 4 4 0 Progressive rod-cone degeneration MFS_1 PF07690.11 EAQ84291.1 - 1.7e-23 82.9 26.5 1.7e-23 82.9 18.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM18 PF14770.1 EAQ84291.1 - 0.005 16.3 1.2 0.022 14.2 0.3 2.5 1 1 1 2 2 2 1 Transmembrane protein 18 F-box PF00646.28 EAQ84292.1 - 1.8e-05 24.2 0.3 4.2e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAQ84292.1 - 0.076 12.7 0.6 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 F-box-like FAD_binding_4 PF01565.18 EAQ84293.1 - 8.8e-18 64.1 0.7 2.3e-17 62.7 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EAQ84293.1 - 3.8e-08 32.4 26.7 7.8e-08 31.4 18.5 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily BBE PF08031.7 EAQ84293.1 - 7.4e-08 32.1 0.2 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF1431 PF07248.7 EAQ84294.1 - 0.1 12.6 5.6 0.22 11.4 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1431) TraN PF06986.6 EAQ84294.1 - 2.2 7.5 6.2 3.8 6.7 4.4 1.4 1 1 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation PIF1 PF05970.9 EAQ84295.1 - 1.3e-17 63.8 0.1 2.3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ84295.1 - 0.00011 21.7 0.1 0.00031 20.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 EAQ84297.1 - 6.1e-07 28.7 0.1 1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Exo_endo_phos_2 PF14529.1 EAQ84299.1 - 1.7e-19 69.5 0.0 9.3e-18 63.9 0.1 3.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84299.1 - 1e-05 25.5 0.1 2.5e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SEEK1 PF15357.1 EAQ84299.1 - 0.067 13.0 1.1 0.23 11.3 0.3 2.2 2 0 0 2 2 2 0 Psoriasis susceptibility 1 candidate 1 Tannase PF07519.6 EAQ84300.1 - 3.2e-87 293.2 0.0 3.6e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EAQ84300.1 - 3.7e-05 23.7 0.3 0.00013 21.8 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ84300.1 - 0.00049 19.3 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EAQ84300.1 - 0.0014 18.2 0.2 0.0032 17.0 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ84300.1 - 0.037 13.7 0.5 0.46 10.2 0.3 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EAQ84300.1 - 0.085 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Methyltransf_25 PF13649.1 EAQ84301.1 - 4.3e-15 55.9 0.0 6.8e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84301.1 - 3e-05 24.4 0.0 0.00012 22.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84301.1 - 0.0054 17.1 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ84301.1 - 0.036 13.6 0.0 0.084 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EAQ84301.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 EAQ84301.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PIF1 PF05970.9 EAQ84302.1 - 1.2e-28 100.1 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAQ84302.1 - 6e-27 94.5 2.6 2.4e-22 79.5 0.1 2.2 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAQ84302.1 - 6.4e-05 22.6 0.0 0.00016 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ84302.1 - 0.0004 20.0 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 EAQ84302.1 - 0.072 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin KAP_NTPase PF07693.9 EAQ84302.1 - 0.39 9.6 0.0 0.57 9.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Esterase_phd PF10503.4 EAQ84303.1 - 7.2e-22 77.7 0.6 1e-21 77.2 0.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EAQ84303.1 - 1.4e-07 30.9 1.0 2.1e-07 30.3 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ84303.1 - 8.9e-06 25.5 0.2 1.3e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAQ84303.1 - 0.0003 19.6 0.1 0.0027 16.4 0.0 2.0 1 1 1 2 2 2 1 Carboxylesterase family Esterase PF00756.15 EAQ84303.1 - 0.0013 18.2 1.2 0.0044 16.4 0.6 2.0 1 1 1 2 2 2 1 Putative esterase Peptidase_S10 PF00450.17 EAQ84303.1 - 0.009 15.2 0.3 0.02 14.0 0.1 1.5 2 0 0 2 2 2 1 Serine carboxypeptidase Abhydrolase_1 PF00561.15 EAQ84303.1 - 0.016 14.8 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EAQ84303.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cellulase PF00150.13 EAQ84304.1 - 1.5e-17 63.7 7.8 2.6e-17 62.9 5.4 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EAQ84304.1 - 7.6e-05 21.7 0.0 0.00048 19.1 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EAQ84304.1 - 7.9e-05 23.0 0.0 0.00022 21.6 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EAQ84304.1 - 0.00012 21.3 0.0 0.00038 19.7 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase CBM_20 PF00686.14 EAQ84305.1 - 1.6e-33 114.1 1.1 3.1e-33 113.2 0.8 1.5 1 0 0 1 1 1 1 Starch binding domain ATP-grasp_4 PF13535.1 EAQ84306.1 - 5.6e-22 78.3 0.0 7.8e-18 64.8 0.0 3.3 1 1 1 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAQ84306.1 - 3.6e-06 26.5 0.0 8.5e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EAQ84306.1 - 2.6e-05 24.1 0.0 0.00056 19.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EAQ84306.1 - 0.0026 17.0 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EAQ84306.1 - 0.005 15.6 0.0 1.2 7.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 EAQ84306.1 - 0.022 14.2 0.0 0.066 12.6 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GARS_A PF01071.14 EAQ84306.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HMGL-like PF00682.14 EAQ84307.1 - 2.2e-47 161.7 0.0 3.4e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Ank PF00023.25 EAQ84308.1 - 6.6e-35 117.1 2.9 3e-09 36.2 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EAQ84308.1 - 3.6e-34 116.9 2.5 9.1e-18 64.3 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ84308.1 - 3.6e-29 100.5 4.4 6.1e-13 48.9 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84308.1 - 5.1e-25 85.0 0.9 1.1e-05 25.1 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EAQ84308.1 - 3.1e-21 74.9 3.9 7.2e-08 32.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EAQ84308.1 - 1e-06 28.5 4.1 1.6e-06 27.9 2.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ84308.1 - 0.0058 16.4 7.8 0.0098 15.6 5.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper ABC_tran PF00005.22 EAQ84309.1 - 1.7e-57 193.5 0.4 2.2e-31 108.9 0.0 3.4 2 1 1 3 3 3 3 ABC transporter ABC_membrane PF00664.18 EAQ84309.1 - 2.9e-50 171.2 34.3 1.2e-35 123.3 12.6 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EAQ84309.1 - 1.2e-15 57.3 4.5 2.6e-06 26.8 0.1 5.1 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ84309.1 - 4e-14 53.2 0.0 0.034 14.1 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_30 PF13604.1 EAQ84309.1 - 9.9e-11 41.5 0.5 0.00021 20.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ84309.1 - 1.1e-10 41.8 5.2 6.4e-05 23.0 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAQ84309.1 - 1.9e-10 40.9 0.4 0.0001 22.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EAQ84309.1 - 3.9e-09 35.9 0.0 0.0012 18.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EAQ84309.1 - 1.8e-08 33.7 0.0 0.0068 15.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAQ84309.1 - 2e-08 35.0 0.0 0.011 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EAQ84309.1 - 8.1e-08 31.2 0.6 0.012 14.2 0.2 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.24 EAQ84309.1 - 2.1e-06 27.9 0.1 0.034 14.3 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAQ84309.1 - 2.9e-06 27.1 0.1 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAQ84309.1 - 2.6e-05 23.7 0.5 0.44 9.9 0.0 3.3 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EAQ84309.1 - 4e-05 22.8 0.9 0.32 10.0 0.0 3.4 3 1 0 3 3 3 2 Zeta toxin AAA_23 PF13476.1 EAQ84309.1 - 4.4e-05 23.8 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EAQ84309.1 - 9.8e-05 22.6 0.0 0.57 10.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EAQ84309.1 - 9.9e-05 22.0 0.1 0.48 10.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EAQ84309.1 - 0.00016 21.2 1.6 1.3 8.4 0.1 3.6 3 1 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EAQ84309.1 - 0.00017 21.4 0.0 1.5 8.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EAQ84309.1 - 0.00022 21.1 5.0 0.27 11.1 0.2 3.4 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EAQ84309.1 - 0.0014 18.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 EAQ84309.1 - 0.0014 17.4 0.0 0.021 13.4 0.0 2.3 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EAQ84309.1 - 0.0018 17.7 1.5 2.4 7.5 0.7 3.2 2 1 0 2 2 2 1 AAA-like domain G-alpha PF00503.15 EAQ84309.1 - 0.002 16.9 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit IstB_IS21 PF01695.12 EAQ84309.1 - 0.0025 17.2 1.7 0.23 10.8 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EAQ84309.1 - 0.0034 17.3 0.2 3.7 7.5 0.0 3.5 3 1 0 3 3 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EAQ84309.1 - 0.017 15.3 0.1 6.3 7.0 0.0 3.0 3 0 0 3 3 2 0 RNA helicase PRK PF00485.13 EAQ84309.1 - 0.024 14.2 0.0 5.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EAQ84309.1 - 0.025 14.2 0.0 5.4 6.7 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EAQ84309.1 - 0.025 14.1 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EAQ84309.1 - 0.025 13.6 0.0 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EAQ84309.1 - 0.029 14.2 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 APS_kinase PF01583.15 EAQ84309.1 - 0.053 13.1 0.1 11 5.6 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Miro PF08477.8 EAQ84309.1 - 0.07 13.6 0.0 9 6.8 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EAQ84309.1 - 0.091 12.4 0.4 7.1 6.2 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_PrkA PF08298.6 EAQ84309.1 - 0.15 10.7 0.1 12 4.4 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain NB-ARC PF00931.17 EAQ84309.1 - 0.18 10.6 0.0 4.7 5.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Aconitase PF00330.15 EAQ84310.1 - 2.4e-83 280.2 0.0 2.8e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAQ84310.1 - 9e-35 119.6 0.0 1.5e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain MFS_1 PF07690.11 EAQ84311.1 - 1.7e-19 69.7 42.3 6.6e-13 48.0 5.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2243 PF10002.4 EAQ84311.1 - 0.014 15.1 2.4 0.055 13.2 0.4 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2243) 2OG-FeII_Oxy PF03171.15 EAQ84312.1 - 5e-10 39.5 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAQ84312.1 - 1e-08 35.6 0.1 4.1e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.17 EAQ84313.1 - 1.2e-32 113.1 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4351 PF14261.1 EAQ84313.1 - 0.18 11.6 2.9 11 5.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) DUF4174 PF13778.1 EAQ84314.1 - 0.028 14.5 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) WHG PF13305.1 EAQ84314.1 - 0.11 13.0 0.1 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 WHG domain Transferase PF02458.10 EAQ84316.1 - 5.4e-18 64.6 0.0 7.3e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family eIF3g PF12353.3 EAQ84317.1 - 0.0061 16.4 1.2 0.018 14.9 0.9 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2113 PF09886.4 EAQ84317.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) RVT_2 PF07727.9 EAQ84318.1 - 9.1e-53 178.7 0.1 6.2e-52 176.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ84318.1 - 2.8e-14 53.2 0.0 8.1e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ84318.1 - 8.7e-08 31.6 0.1 1.8e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 EAQ84319.1 - 4.9e-25 88.1 0.0 8.2e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84319.1 - 1.8e-06 27.5 0.5 4.8e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase CDC45 PF02724.9 EAQ84320.1 - 0.13 10.2 4.5 0.2 9.6 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_1 PF00078.22 EAQ84321.1 - 6.5e-27 94.2 0.0 1.3e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 EAQ84323.1 - 8.2e-46 156.4 0.0 1.3e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EAQ84323.1 - 3.7e-27 95.5 1.8 6.5e-27 94.7 1.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ84323.1 - 8.1e-12 45.3 3.3 9.8e-12 45.1 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ84323.1 - 2.7e-07 30.8 0.2 0.0002 21.4 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EAQ84323.1 - 9.4e-06 25.8 0.1 2.7e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 EAQ84323.1 - 1.4 8.6 6.2 6.6 6.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding LVIVD PF08309.6 EAQ84324.1 - 0.0017 17.2 0.3 13 4.8 0.0 4.1 4 0 0 4 4 4 3 LVIVD repeat Beta_propel PF09826.4 EAQ84324.1 - 0.072 11.4 0.1 0.3 9.3 0.0 1.8 1 1 2 3 3 3 0 Beta propeller domain DUF1989 PF09347.5 EAQ84325.1 - 3.5e-52 176.1 0.0 5e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_3 PF07859.8 EAQ84326.1 - 3e-14 53.1 0.0 3.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_lyase PF14099.1 EAQ84327.1 - 1.9e-47 161.7 0.8 2.2e-47 161.5 0.5 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Sugar_tr PF00083.19 EAQ84328.1 - 6.6e-78 262.2 25.5 7.8e-78 262.0 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84328.1 - 1.8e-25 89.3 25.5 1.1e-22 80.2 11.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ84328.1 - 3.3e-06 25.7 2.1 3.3e-06 25.7 1.5 3.0 2 2 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EAQ84328.1 - 0.00011 20.6 2.0 0.00016 20.0 1.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gate PF07670.9 EAQ84328.1 - 0.94 9.4 5.9 1.5 8.7 0.1 3.0 2 1 1 3 3 3 0 Nucleoside recognition CobT PF06213.7 EAQ84330.1 - 8.7 5.3 7.9 8.2 5.4 5.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Exo_endo_phos_2 PF14529.1 EAQ84331.1 - 2.1e-08 33.7 0.0 2.2e-07 30.4 0.0 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84331.1 - 1.3e-05 25.2 0.1 2.7e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EAQ84332.1 - 4.5e-15 55.5 0.0 1.4e-09 37.6 0.0 2.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) UreE_N PF02814.10 EAQ84332.1 - 0.078 12.5 0.2 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain RVT_2 PF07727.9 EAQ84333.1 - 1e-36 126.1 0.0 7.4e-34 116.8 0.0 2.4 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EAQ84333.1 - 0.00044 19.6 0.0 0.00086 18.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EAQ84334.1 - 2.6e-32 111.9 0.0 5.4e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EAQ84334.1 - 0.012 15.5 2.4 0.012 15.5 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle M20_dimer PF07687.9 EAQ84335.1 - 0.0078 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EAQ84335.1 - 0.11 12.0 0.9 0.31 10.5 0.5 1.9 1 1 1 2 2 2 0 Peptidase family M20/M25/M40 2OG-FeII_Oxy PF03171.15 EAQ84337.1 - 1.1e-13 51.3 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAQ84337.1 - 3.3e-11 43.7 0.0 6.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3712 PF12505.3 EAQ84338.1 - 4.9e-27 94.4 0.1 7.8e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) PAH PF02671.16 EAQ84338.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Paired amphipathic helix repeat MULE PF10551.4 EAQ84339.1 - 3.2e-09 36.8 0.4 6.7e-08 32.5 0.3 2.4 1 1 0 1 1 1 1 MULE transposase domain CDK5_activator PF03261.10 EAQ84339.1 - 7.8 5.7 13.1 8.4 5.6 7.4 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Hce2 PF14856.1 EAQ84340.1 - 1.2e-25 89.2 0.1 2e-25 88.4 0.0 1.4 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor DHC_N1 PF08385.7 EAQ84341.1 - 0.044 12.1 3.1 22 3.2 0.0 4.1 2 1 3 5 5 5 0 Dynein heavy chain, N-terminal region 1 CRAL_TRIO PF00650.15 EAQ84342.1 - 2.6e-40 137.4 0.1 4.7e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAQ84342.1 - 4e-14 52.4 0.5 1.7e-13 50.4 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EAQ84342.1 - 3.5e-08 33.4 0.0 6.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Abhydrolase_3 PF07859.8 EAQ84343.1 - 9.9e-29 100.4 0.0 1.7e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pyr_redox_3 PF13738.1 EAQ84343.1 - 2.1e-25 89.9 0.0 4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ84343.1 - 2.5e-10 39.1 0.0 1.2e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EAQ84343.1 - 4.4e-10 39.4 0.1 6.4e-08 32.5 0.0 3.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DUF2424 PF10340.4 EAQ84343.1 - 5.2e-10 38.4 0.0 5.4e-09 35.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2424) K_oxygenase PF13434.1 EAQ84343.1 - 2.1e-05 23.6 0.2 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EAQ84343.1 - 8.7e-05 21.7 0.0 0.0061 15.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EAQ84343.1 - 0.00019 20.4 0.2 0.0069 15.3 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Abhydrolase_5 PF12695.2 EAQ84343.1 - 0.00068 19.4 0.1 0.0017 18.1 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox PF00070.22 EAQ84343.1 - 0.0015 18.8 0.3 0.15 12.4 0.0 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ84343.1 - 0.0053 16.6 0.7 2.3 8.0 0.0 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EAQ84343.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF498 PF04430.9 EAQ84343.1 - 0.017 14.6 0.0 1.4 8.5 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF498/DUF598) Shikimate_DH PF01488.15 EAQ84343.1 - 0.032 14.3 0.0 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EAQ84343.1 - 0.058 12.2 2.0 0.26 10.0 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.10 EAQ84343.1 - 0.1 10.7 0.0 0.18 9.9 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EAQ84343.1 - 0.6 9.8 2.5 9.7 5.9 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding adh_short PF00106.20 EAQ84344.1 - 3.3e-30 105.2 0.2 5.6e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ84344.1 - 6.2e-11 42.5 0.0 8.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ84344.1 - 1e-09 38.3 1.0 3.6e-09 36.5 0.7 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EAQ84344.1 - 4.6e-05 22.2 0.0 6.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ84344.1 - 7.5e-05 22.2 0.0 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ84344.1 - 9.7e-05 22.4 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EAQ84344.1 - 0.065 12.3 0.1 0.094 11.8 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 EAQ84344.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 EAQ84345.1 - 1.5e-08 33.6 0.2 2.2e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3543 PF12063.3 EAQ84345.1 - 0.05 12.8 0.1 0.089 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) p450 PF00067.17 EAQ84346.1 - 3.6e-78 263.1 0.0 4.4e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EAQ84347.1 - 8.6e-82 275.0 0.0 1.1e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ84347.1 - 0.00049 20.0 0.0 0.0022 17.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ84347.1 - 0.0022 16.9 1.5 0.05 12.4 0.7 2.3 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EAQ84347.1 - 0.0054 15.6 0.8 0.014 14.2 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ84347.1 - 0.017 15.1 1.8 0.036 14.0 1.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ84347.1 - 0.045 12.6 0.1 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EAQ84347.1 - 0.076 12.0 0.2 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EAQ84347.1 - 0.11 12.8 0.1 0.43 11.0 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1889 PF08986.5 EAQ84347.1 - 0.13 12.4 0.0 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) Pyr_redox_3 PF13738.1 EAQ84347.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RVT_1 PF00078.22 EAQ84348.1 - 9.9e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EAQ84348.1 - 0.037 14.3 1.6 0.051 13.8 0.2 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase RVT_3 PF13456.1 EAQ84348.1 - 0.042 13.6 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like MARVEL PF01284.18 EAQ84349.1 - 0.031 14.0 19.7 0.064 13.0 13.7 1.5 1 1 0 1 1 1 0 Membrane-associating domain PDR_assoc PF08370.6 EAQ84349.1 - 0.95 9.0 6.1 9.9 5.7 0.2 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Ycf9 PF01737.12 EAQ84349.1 - 5.4 6.5 14.2 0.93 8.9 1.6 2.8 2 1 0 2 2 2 0 YCF9 ADH_N PF08240.7 EAQ84351.1 - 2.3e-24 85.2 0.5 4.1e-24 84.4 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EAQ84351.1 - 1.6e-10 40.4 1.2 1.6e-10 40.4 0.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EAQ84351.1 - 1.4e-05 24.5 0.1 0.0001 21.8 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Lipase_3 PF01764.20 EAQ84352.1 - 4.8e-06 26.2 0.0 2.2e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Lipase (class 3) Serglycin PF04360.7 EAQ84353.1 - 4.9 6.8 11.2 6.1 6.5 6.9 1.8 2 0 0 2 2 2 0 Serglycin Rft-1 PF04506.8 EAQ84354.1 - 6e-77 259.2 0.0 9.8e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EAQ84354.1 - 7.8e-05 22.0 2.7 7.8e-05 22.0 1.9 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DUF594 PF04578.8 EAQ84355.1 - 0.11 11.9 0.1 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF594 DEAD PF00270.24 EAQ84356.1 - 1.2e-46 158.2 0.0 9.6e-45 152.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ84356.1 - 1.6e-29 101.5 0.0 1.8e-28 98.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Daxx PF03344.10 EAQ84356.1 - 0.14 10.5 24.3 0.2 10.1 16.8 1.1 1 0 0 1 1 1 0 Daxx Family Mem_trans PF03547.13 EAQ84356.1 - 0.19 9.9 0.1 0.2 9.9 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein CMS1 PF14617.1 EAQ84356.1 - 0.29 10.1 0.0 0.29 10.1 0.0 3.5 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EAQ84356.1 - 0.36 9.1 0.0 0.36 9.1 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1253) Menin PF05053.8 EAQ84356.1 - 3.2 5.8 12.0 4.4 5.3 8.3 1.2 1 0 0 1 1 1 0 Menin Cauli_VI PF01693.11 EAQ84359.1 - 8.7e-34 115.2 11.0 4.1e-18 65.1 1.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EAQ84359.1 - 3e-28 98.7 0.0 5.2e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 RNase H TRP PF06011.7 EAQ84360.1 - 3.4e-146 487.2 33.0 4.2e-146 486.9 22.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAQ84360.1 - 8.8e-42 142.4 0.3 1.5e-41 141.7 0.2 1.4 1 0 0 1 1 1 1 ML-like domain DUF1049 PF06305.6 EAQ84360.1 - 0.007 15.8 0.1 0.007 15.8 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) Ank_2 PF12796.2 EAQ84361.1 - 1.9e-14 53.7 0.0 3.1e-07 30.6 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84361.1 - 2.2e-12 46.1 6.0 0.0015 18.2 0.0 6.6 6 2 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EAQ84361.1 - 7.2e-12 45.1 7.4 0.00025 21.1 0.1 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84361.1 - 1.7e-10 40.0 1.7 0.72 10.2 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EAQ84361.1 - 1.8e-09 37.8 1.1 0.0011 19.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) F-box PF00646.28 EAQ84361.1 - 0.00073 19.1 0.1 0.00073 19.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain S1FA PF04689.8 EAQ84362.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA SKG6 PF08693.5 EAQ84362.1 - 0.24 10.7 2.9 0.49 9.7 2.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HORMA PF02301.13 EAQ84363.1 - 4.7e-46 156.9 0.0 5.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 HORMA domain DUF2411 PF10304.4 EAQ84363.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) UCH PF00443.24 EAQ84364.1 - 2.2e-40 138.4 0.0 3.3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAQ84364.1 - 1.4e-25 89.1 10.7 2.5e-20 72.3 1.6 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EAQ84364.1 - 1.2e-16 60.0 0.1 4.2e-07 29.6 0.0 2.9 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.1 EAQ84364.1 - 2.1e-16 60.2 0.0 3.5e-08 33.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Aa_trans PF01490.13 EAQ84366.1 - 1.8e-38 132.1 18.0 1.3e-21 76.5 6.2 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Abhydrolase_6 PF12697.2 EAQ84367.1 - 0.00035 20.5 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ84367.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ84367.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NifU_N PF01592.11 EAQ84369.1 - 2.2e-47 160.1 0.0 3.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Acetyltransf_1 PF00583.19 EAQ84369.1 - 0.0027 17.6 0.1 0.0077 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ84369.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DDE_1 PF03184.14 EAQ84370.1 - 2.7e-23 82.2 0.0 6.2e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ84370.1 - 8.6e-14 50.8 0.0 2.7e-13 49.2 0.0 2.0 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ84370.1 - 9.4e-09 34.9 0.0 2.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Myosin_tail_1 PF01576.14 EAQ84370.1 - 0.0022 15.7 12.7 0.0034 15.1 8.8 1.2 1 0 0 1 1 1 1 Myosin tail DUF3584 PF12128.3 EAQ84370.1 - 0.0095 13.3 14.6 0.013 12.8 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SpoIIID PF12116.3 EAQ84370.1 - 0.026 14.4 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Stage III sporulation protein D AAA_13 PF13166.1 EAQ84370.1 - 0.033 12.6 8.8 0.047 12.1 6.1 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EAQ84370.1 - 0.066 13.0 5.3 4.4 7.1 3.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.16 EAQ84370.1 - 0.17 11.2 12.6 0.46 9.9 8.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein AAA_27 PF13514.1 EAQ84370.1 - 0.22 9.1 17.3 0.34 8.5 12.0 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.1 EAQ84370.1 - 0.24 11.4 6.4 1.9 8.5 2.9 2.7 1 1 1 2 2 2 0 Syntaxin-like protein Reo_sigmaC PF04582.7 EAQ84370.1 - 0.72 8.9 8.4 0.12 11.5 1.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein She9_MDM33 PF05546.6 EAQ84370.1 - 1.4 8.4 6.4 5.6 6.4 0.1 2.3 1 1 1 2 2 2 0 She9 / Mdm33 family Baculo_PEP_C PF04513.7 EAQ84370.1 - 1.7 8.4 7.6 3.7 7.3 2.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EAQ84370.1 - 1.9 8.0 9.7 8 6.0 6.7 2.0 1 1 0 1 1 1 0 IncA protein FliJ PF02050.11 EAQ84370.1 - 2.2 8.3 16.8 2.5 8.1 0.2 2.9 1 1 0 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.1 EAQ84370.1 - 4.8 6.0 19.8 10 4.9 9.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) COG2 PF06148.6 EAQ84370.1 - 5.8 6.8 6.1 20 5.0 0.4 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Muted PF14942.1 EAQ84370.1 - 7.3 6.4 7.2 12 5.8 4.1 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF2937 PF11157.3 EAQ84370.1 - 8.2 5.7 14.5 75 2.6 6.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) NACHT PF05729.7 EAQ84371.1 - 3.2e-05 23.6 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ84371.1 - 0.0007 19.7 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank PF00023.25 EAQ84371.1 - 0.0012 18.5 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EAQ84371.1 - 0.0021 18.3 0.1 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAQ84371.1 - 0.0022 18.0 0.0 0.0078 16.3 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat AAA_17 PF13207.1 EAQ84371.1 - 0.0057 17.4 0.0 0.02 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.1 EAQ84371.1 - 0.0068 16.8 0.1 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ84371.1 - 0.022 15.0 0.1 0.07 13.4 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA_16 PF13191.1 EAQ84371.1 - 0.028 14.4 0.0 0.086 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 EAQ84371.1 - 0.03 13.2 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EAQ84371.1 - 0.04 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EAQ84371.1 - 0.073 13.3 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EAQ84371.1 - 0.094 12.9 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CR6_interact PF10147.4 EAQ84372.1 - 0.0053 16.1 0.5 0.011 15.0 0.4 1.6 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1993 PF09351.5 EAQ84372.1 - 0.027 14.3 10.5 3.7 7.4 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) DinB_2 PF12867.2 EAQ84372.1 - 0.26 11.6 1.5 7.1 6.9 0.2 3.2 3 1 0 3 3 3 0 DinB superfamily V-SNARE PF05008.10 EAQ84372.1 - 0.28 11.3 10.1 0.89 9.7 0.7 3.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MutS_III PF05192.13 EAQ84372.1 - 0.38 10.5 12.1 4.5 7.0 0.2 2.4 1 1 0 2 2 2 0 MutS domain III DUF4206 PF13901.1 EAQ84372.1 - 0.63 9.5 7.7 4.8 6.6 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4206) DMPK_coil PF08826.5 EAQ84372.1 - 1.9 8.4 12.1 2.2 8.2 3.2 3.2 3 0 0 3 3 3 0 DMPK coiled coil domain like Toxin_2 PF00451.14 EAQ84372.1 - 2.1 8.5 6.7 3.4 7.8 0.1 2.8 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Ndc1_Nup PF09531.5 EAQ84372.1 - 7.5 4.8 9.7 9.4 4.5 5.1 1.9 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup AATF-Che1 PF13339.1 EAQ84372.1 - 7.8 6.6 13.0 2.9 8.0 2.4 3.7 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor Glyco_hydro_2_N PF02837.13 EAQ84373.1 - 5.9e-42 143.0 0.1 7.9e-39 132.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EAQ84373.1 - 6.2e-31 107.3 0.0 1.2e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EAQ84373.1 - 2e-16 60.3 0.4 5.9e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EAQ84373.1 - 3.1e-05 24.2 0.1 0.0028 17.8 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DUF1034 PF06280.7 EAQ84373.1 - 0.0074 16.6 1.0 0.021 15.2 0.2 2.1 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) APH PF01636.18 EAQ84374.1 - 1.1e-16 61.3 0.1 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ84374.1 - 2.6e-05 23.9 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EAQ84374.1 - 0.094 11.8 0.0 0.57 9.2 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase RVT_1 PF00078.22 EAQ84379.1 - 9.3e-13 48.0 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ84379.1 - 1.2e-11 44.0 5.5 2.7e-11 42.9 3.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EAQ84379.1 - 2.1e-10 40.7 0.0 6.2e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain CAF-1_p150 PF11600.3 EAQ84379.1 - 2.3 7.5 22.9 4.5 6.5 15.9 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDE_1 PF03184.14 EAQ84380.1 - 2.4e-49 167.3 0.0 4.1e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EAQ84380.1 - 1.5e-36 125.8 0.0 2.6e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84380.1 - 5.5e-12 45.3 0.0 1.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HTH_psq PF05225.11 EAQ84380.1 - 2.7e-06 26.8 0.0 1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Exo_endo_phos PF03372.18 EAQ84380.1 - 9.5e-06 25.7 0.1 1.9e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc5 PF03221.11 EAQ84380.1 - 0.016 15.0 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Peptidase_S8 PF00082.17 EAQ84381.1 - 3.9e-34 118.0 7.7 5.9e-34 117.4 5.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAQ84381.1 - 1.3e-11 44.8 0.1 2.2e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_16 PF00722.16 EAQ84383.1 - 7.6e-19 67.7 0.0 1.5e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EAQ84383.1 - 1.6e-06 26.5 0.3 0.0019 16.4 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Ank_2 PF12796.2 EAQ84384.1 - 5.3e-108 353.6 13.1 4.4e-19 68.6 0.1 7.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84384.1 - 5.3e-103 332.0 35.1 9.2e-10 37.8 0.1 15.2 15 0 0 15 15 15 15 Ankyrin repeat Ank_4 PF13637.1 EAQ84384.1 - 5.9e-72 236.8 17.4 6.7e-11 42.4 0.0 10.2 5 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84384.1 - 2.5e-70 225.3 16.2 2.8e-05 23.9 0.0 15.2 15 0 0 15 15 15 15 Ankyrin repeat Ank_5 PF13857.1 EAQ84384.1 - 1e-59 197.1 32.8 3.8e-09 36.5 0.5 14.4 1 1 14 15 15 15 15 Ankyrin repeats (many copies) Clr5 PF14420.1 EAQ84384.1 - 2.2e-12 46.6 2.6 3.6e-12 45.9 1.8 1.4 1 0 0 1 1 1 1 Clr5 domain DUF1843 PF08898.5 EAQ84384.1 - 0.14 12.2 7.3 2.1 8.4 0.1 5.2 6 1 0 6 6 6 0 Domain of unknown function (DUF1843) GMC_oxred_N PF00732.14 EAQ84387.1 - 4.2e-37 127.8 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ84387.1 - 8.2e-24 84.5 0.0 1.7e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase PAT1 PF09770.4 EAQ84390.1 - 6.5 4.8 19.9 8 4.5 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRAPP PF04051.11 EAQ84391.1 - 7e-37 126.2 0.0 8.2e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EAQ84392.1 - 4e-51 169.1 6.4 2.7e-09 36.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAQ84392.1 - 0.0038 16.0 1.1 1.1 7.8 0.2 3.2 1 1 2 3 3 3 2 Nup133 N terminal like zf-CCHC PF00098.18 EAQ84394.1 - 5e-41 136.7 56.5 2.2e-07 30.4 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EAQ84394.1 - 1.2e-11 44.0 44.8 0.0038 16.8 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EAQ84394.1 - 0.00011 21.8 41.2 0.53 10.0 0.3 7.0 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_6 PF15288.1 EAQ84394.1 - 0.15 11.7 0.4 0.15 11.7 0.3 7.1 6 1 2 8 8 8 0 Zinc knuckle DUF1237 PF06824.6 EAQ84395.1 - 1.4e-136 455.5 0.0 1.3e-109 366.6 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1237) Hydrolase_6 PF13344.1 EAQ84396.1 - 2.1e-22 78.9 0.0 8.8e-22 76.9 0.0 2.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ84396.1 - 3.8e-11 42.5 0.0 1.7e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EAQ84396.1 - 0.015 15.6 0.0 0.055 13.8 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ84396.1 - 0.09 12.9 0.0 13 5.9 0.0 2.7 2 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF2793 PF10983.3 EAQ84399.1 - 0.024 14.4 0.0 0.079 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) tRNA-synt_1 PF00133.17 EAQ84400.1 - 1.4e-105 353.5 0.0 6.9e-46 156.4 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAQ84400.1 - 1.6e-18 66.9 0.0 3.2e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAQ84400.1 - 1.6e-08 33.6 0.2 7.5e-05 21.5 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EAQ84400.1 - 0.0052 15.9 0.0 0.04 13.0 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Defensin_big PF14862.1 EAQ84401.1 - 5.1 7.2 10.3 24 5.0 7.1 1.9 1 1 0 1 1 1 0 Big defensin adh_short_C2 PF13561.1 EAQ84402.1 - 9.8e-34 117.1 0.1 1.2e-33 116.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ84402.1 - 3.1e-32 111.8 1.1 5.3e-32 111.0 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ84402.1 - 4.2e-14 52.6 0.2 6.3e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAQ84402.1 - 1.7e-05 24.8 0.4 3.4e-05 23.9 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ84402.1 - 0.00083 18.8 0.1 0.012 15.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAQ84402.1 - 0.081 12.7 1.5 0.59 9.9 0.1 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 EAQ84403.1 - 3.1e-18 66.5 0.0 4.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ84403.1 - 1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ84403.1 - 0.053 13.3 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase CFEM PF05730.6 EAQ84404.1 - 9.2e-13 47.8 6.6 1.7e-12 46.9 4.6 1.5 1 0 0 1 1 1 1 CFEM domain MLANA PF14991.1 EAQ84404.1 - 0.039 13.9 0.5 0.15 12.0 0.0 2.2 2 1 1 3 3 3 0 Protein melan-A TFIIA PF03153.8 EAQ84404.1 - 2.6 7.8 6.4 3.2 7.5 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EAQ84404.1 - 3.5 5.8 5.9 3.7 5.7 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_BLLF1 PF05109.8 EAQ84404.1 - 5.8 4.7 28.7 7.4 4.3 19.9 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF566 PF04484.7 EAQ84404.1 - 5.9 6.2 11.4 7.5 5.9 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_L22 PF00237.14 EAQ84405.1 - 2.7e-14 52.9 0.5 1e-06 28.6 0.2 2.5 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e SKG6 PF08693.5 EAQ84406.1 - 0.0074 15.5 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EAQ84406.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Lamp PF01299.12 EAQ84406.1 - 6.7 5.7 6.3 0.44 9.6 0.1 2.0 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF3112 PF11309.3 EAQ84407.1 - 9.6e-46 155.4 0.9 9.6e-46 155.4 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) TMEM169 PF15052.1 EAQ84407.1 - 1.1 9.1 4.1 12 5.7 0.8 2.4 2 0 0 2 2 2 0 TMEM169 protein family WD40 PF00400.27 EAQ84409.1 - 3.4e-61 201.1 24.6 4.5e-11 42.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAQ84409.1 - 5e-06 24.9 5.0 0.14 10.2 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EAQ84409.1 - 0.041 12.1 0.0 4.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Bromo_TP PF07524.8 EAQ84410.1 - 3.5e-16 58.6 0.0 6.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EAQ84410.1 - 2.9e-11 43.2 0.4 2.4e-05 24.3 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term LRR_8 PF13855.1 EAQ84411.1 - 5e-16 58.2 15.1 2.5e-09 36.7 0.8 2.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EAQ84411.1 - 5.2e-14 51.4 1.4 5.4e-05 22.6 0.8 3.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EAQ84411.1 - 8.7e-08 31.1 7.0 0.057 13.4 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EAQ84411.1 - 0.037 14.2 10.2 1.3 9.5 0.1 4.6 5 0 0 5 5 5 0 Leucine rich repeat Ribosomal_60s PF00428.14 EAQ84411.1 - 0.038 14.3 2.0 0.067 13.5 1.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase_Tyr PF07714.12 EAQ84411.1 - 0.04 12.9 0.0 1.3 8.0 0.0 2.2 2 1 1 3 3 3 0 Protein tyrosine kinase Isochorismatase PF00857.15 EAQ84412.1 - 3.7e-27 95.3 0.0 1.6e-26 93.2 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 EAQ84412.1 - 1.7e-25 90.0 0.0 2.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 EAQ84412.1 - 8.5e-06 26.1 0.0 2.5e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ84412.1 - 0.0067 16.2 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SHMT PF00464.14 EAQ84413.1 - 3.2e-109 364.9 0.0 3.9e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EAQ84413.1 - 0.0013 17.5 0.0 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAQ84413.1 - 0.0036 16.4 0.0 0.0057 15.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EAQ84413.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Ribosomal_L19e PF01280.15 EAQ84414.1 - 1.4e-61 206.5 7.0 1.4e-61 206.5 4.8 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EAQ84414.1 - 0.14 11.3 1.8 0.14 11.3 1.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Atg14 PF10186.4 EAQ84414.1 - 1.6 7.5 7.8 2.4 7.0 5.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3554 PF12074.3 EAQ84415.1 - 3.6e-104 348.8 5.7 2.5e-102 342.7 0.0 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EAQ84415.1 - 5.2e-41 135.0 35.3 0.0059 16.5 0.0 24.5 27 0 0 27 27 25 8 HEAT repeat HEAT_2 PF13646.1 EAQ84415.1 - 6.6e-36 122.4 64.5 1.8e-09 37.7 0.0 18.0 11 3 7 18 18 16 9 HEAT repeats HEAT_EZ PF13513.1 EAQ84415.1 - 2.2e-29 101.1 70.8 7.1e-07 29.5 0.0 23.6 18 3 8 26 26 24 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAQ84415.1 - 4.1e-15 55.9 0.0 1.2 9.5 0.0 10.0 8 2 2 10 10 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EAQ84415.1 - 8.5e-14 51.4 0.0 0.003 16.9 0.0 7.1 4 2 5 9 9 9 5 CLASP N terminal ParcG PF10274.4 EAQ84415.1 - 3.2e-13 49.9 0.6 9.2e-05 22.4 0.0 5.6 4 1 1 5 5 5 3 Parkin co-regulated protein Adaptin_N PF01602.15 EAQ84415.1 - 2.8e-10 39.1 9.2 0.0051 15.1 0.4 7.9 5 4 2 7 7 7 3 Adaptin N terminal region Cnd1 PF12717.2 EAQ84415.1 - 7.8e-10 38.8 0.0 2.6 7.8 0.2 8.9 6 3 3 9 9 9 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EAQ84415.1 - 3.8e-09 36.4 0.0 9.1 6.2 0.0 8.1 6 2 2 9 9 9 0 UME (NUC010) domain Ipi1_N PF12333.3 EAQ84415.1 - 5e-06 26.4 1.8 0.003 17.4 0.0 6.0 7 0 0 7 7 5 1 Rix1 complex component involved in 60S ribosome maturation DUF3535 PF12054.3 EAQ84415.1 - 0.00074 18.2 1.4 0.063 11.9 0.0 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3535) TFCD_C PF12612.3 EAQ84415.1 - 0.0026 17.2 3.3 0.016 14.6 0.2 4.0 4 1 0 4 4 3 1 Tubulin folding cofactor D C terminal MMS19_N PF14500.1 EAQ84415.1 - 0.016 14.4 0.4 5.3 6.2 0.0 5.0 5 1 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EAQ84415.1 - 0.018 13.8 9.6 1.1 7.9 0.2 5.6 5 1 0 6 6 6 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 EAQ84415.1 - 0.09 13.2 32.3 0.66 10.6 0.1 11.4 11 0 0 11 11 11 0 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.2 EAQ84415.1 - 0.11 12.4 8.0 17 5.4 0.2 6.9 6 0 0 6 6 5 0 HEAT repeat associated with sister chromatid cohesion HA2 PF04408.18 EAQ84416.1 - 2.3e-17 62.8 0.0 6.9e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAQ84416.1 - 2.6e-12 46.4 0.0 6.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ84416.1 - 2.2e-10 40.2 0.1 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAQ84416.1 - 4.8e-08 33.2 0.1 1.6e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 EAQ84416.1 - 4.3e-07 29.7 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 EAQ84416.1 - 0.0013 18.1 0.0 0.0036 16.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EAQ84416.1 - 0.031 13.7 0.0 0.11 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ84416.1 - 0.053 13.8 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EAQ84416.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 EAQ84416.1 - 0.081 12.4 0.1 1.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain NB-ARC PF00931.17 EAQ84416.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EAQ84416.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Patatin PF01734.17 EAQ84418.1 - 4.1e-27 95.4 0.0 9.4e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EAQ84418.1 - 2.3e-09 36.5 0.0 4.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EAQ84418.1 - 3.9e-06 27.0 0.0 1.6e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 EAQ84418.1 - 0.0002 21.2 12.4 0.0035 17.2 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_14 PF13173.1 EAQ84418.1 - 0.0073 16.2 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ84418.1 - 0.041 13.5 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 EAQ84418.1 - 0.043 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TPR_11 PF13414.1 EAQ84418.1 - 0.1 12.2 4.1 0.31 10.7 0.1 3.1 3 0 0 3 3 3 0 TPR repeat GvpD PF07088.6 EAQ84418.1 - 0.11 10.7 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein TPR_10 PF13374.1 EAQ84418.1 - 0.23 11.4 11.4 1 9.3 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PUL PF08324.6 EAQ84418.1 - 0.23 10.2 0.2 0.63 8.7 0.0 1.7 2 0 0 2 2 2 0 PUL domain Abhydrolase_3 PF07859.8 EAQ84420.1 - 1.2e-32 113.2 0.3 1.5e-32 112.9 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EAQ84421.1 - 8e-23 80.2 0.0 2.1e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ84421.1 - 5.1e-11 42.5 0.0 1.7e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ84421.1 - 6.6e-10 39.2 0.0 5.5e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ84421.1 - 0.0002 21.1 0.0 0.0065 16.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 EAQ84422.1 - 1.7e-24 86.1 0.1 1.7e-24 86.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ84422.1 - 4.1e-08 32.9 10.5 6.7e-08 32.3 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EAQ84423.1 - 8.3e-21 74.0 0.0 2.5e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EAQ84423.1 - 8.6e-14 51.8 0.0 2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EAQ84423.1 - 1.7e-10 40.9 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 EAQ84423.1 - 0.14 11.2 0.0 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase adh_short PF00106.20 EAQ84424.1 - 6.1e-24 84.8 3.8 8.3e-24 84.3 2.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ84424.1 - 6.5e-19 68.6 0.0 7.8e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ84424.1 - 2.3e-08 33.9 1.2 3.5e-08 33.3 0.8 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ84424.1 - 0.019 14.7 0.2 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EAQ84424.1 - 0.055 12.5 0.1 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HHH_5 PF14520.1 EAQ84424.1 - 0.072 13.2 0.1 3 8.0 0.0 2.9 2 1 0 2 2 2 0 Helix-hairpin-helix domain 2OG-FeII_Oxy PF03171.15 EAQ84425.1 - 5.8e-14 52.1 0.0 1.4e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAQ84425.1 - 7.3e-14 52.2 0.0 1.5e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FAD_binding_4 PF01565.18 EAQ84426.1 - 6e-28 97.0 1.5 6e-28 97.0 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain NTP_transf_3 PF12804.2 EAQ84426.1 - 0.0007 19.7 0.8 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 MobA-like NTP transferase domain BBE PF08031.7 EAQ84426.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Cupin_2 PF07883.6 EAQ84427.1 - 2.3e-07 30.2 0.1 4.6e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 EAQ84428.1 - 4.1e-12 46.3 1.6 1.6e-11 44.4 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ84428.1 - 3.7e-05 23.4 0.8 8.2e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ84428.1 - 0.022 14.5 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2101 PF09874.4 EAQ84429.1 - 0.23 10.9 0.1 0.23 10.9 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) FAD_binding_4 PF01565.18 EAQ84430.1 - 9.4e-27 93.1 2.3 1.7e-26 92.3 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain DUF605 PF04652.11 EAQ84430.1 - 0.71 9.1 15.3 1.1 8.6 10.6 1.2 1 0 0 1 1 1 0 Vta1 like Methyltransf_18 PF12847.2 EAQ84431.1 - 1.7e-10 41.4 0.1 2.6e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84431.1 - 3.6e-10 40.1 0.0 6.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ84431.1 - 4.4e-09 36.1 0.0 5.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ84431.1 - 7.3e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ84431.1 - 5.2e-06 26.4 0.4 9e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84431.1 - 3e-05 24.4 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ84431.1 - 0.00043 20.5 0.0 0.0007 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Spore_YpjB PF09577.5 EAQ84431.1 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Hce2 PF14856.1 EAQ84432.1 - 1.7e-12 47.0 0.0 2.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor NACHT PF05729.7 EAQ84433.1 - 1.8e-08 34.2 0.0 3.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ84433.1 - 0.00022 21.2 0.0 0.00073 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ84433.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAQ84433.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAQ84433.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EAQ84433.1 - 0.15 12.9 0.1 1.8 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.4 EAQ84434.1 - 0.8 9.1 20.3 1.2 8.5 14.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tyrosinase PF00264.15 EAQ84435.1 - 6.8e-16 59.1 11.0 4.2e-13 49.9 1.4 3.5 2 1 0 3 3 3 2 Common central domain of tyrosinase Tropomyosin_1 PF12718.2 EAQ84435.1 - 0.0072 16.1 25.5 0.0072 16.1 17.7 2.8 1 1 2 3 3 3 1 Tropomyosin like DUF904 PF06005.7 EAQ84435.1 - 0.015 15.5 1.9 0.015 15.5 1.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF904) ATG16 PF08614.6 EAQ84435.1 - 0.26 11.0 29.2 0.047 13.5 3.6 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EAQ84435.1 - 1.6 8.2 35.5 1.4e+03 -1.3 8.6 3.2 1 1 1 2 2 2 0 IncA protein FlaC_arch PF05377.6 EAQ84435.1 - 1.7 8.5 10.1 0.15 11.9 1.3 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EAQ84435.1 - 2.5 7.9 4.9 3.8 7.3 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HR1 PF02185.11 EAQ84435.1 - 2.8 7.7 19.0 1.1 9.0 0.7 4.2 3 1 1 4 4 4 0 Hr1 repeat V_ATPase_I PF01496.14 EAQ84435.1 - 4.7 4.9 10.3 8.1 4.1 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 EAQ84435.1 - 9.9 5.3 24.3 0.06 12.5 9.4 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HET PF06985.6 EAQ84436.1 - 2.5e-32 111.9 0.0 8.8e-32 110.1 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_transf_8 PF01501.15 EAQ84438.1 - 0.0014 17.9 0.3 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EAQ84438.1 - 0.0025 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3530 PF12048.3 EAQ84438.1 - 0.092 11.7 1.1 0.14 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PRCC PF10253.4 EAQ84438.1 - 0.23 12.1 0.8 0.36 11.5 0.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4171 PF13775.1 EAQ84439.1 - 0.035 14.2 3.5 0.045 13.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Macoilin PF09726.4 EAQ84439.1 - 8.8 4.4 8.1 10 4.2 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 EAQ84439.1 - 9.6 5.6 15.0 13 5.1 10.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tom37 PF10568.4 EAQ84440.1 - 0.029 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Exo_endo_phos_2 PF14529.1 EAQ84441.1 - 9.8e-15 54.2 0.0 1.2e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84441.1 - 0.00042 20.3 0.1 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EAQ84441.1 - 0.0016 17.8 0.0 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SlyX PF04102.7 EAQ84441.1 - 0.0046 17.2 4.0 0.1 12.9 1.5 2.8 1 1 1 2 2 2 2 SlyX DUF4226 PF10774.4 EAQ84441.1 - 0.026 14.5 1.3 0.079 13.0 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) CorA PF01544.13 EAQ84441.1 - 0.086 11.8 2.2 0.16 10.9 1.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_lysis PF03245.8 EAQ84441.1 - 0.11 12.5 7.1 0.16 11.9 0.8 3.3 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Mnd1 PF03962.10 EAQ84441.1 - 0.37 10.4 1.9 0.76 9.4 1.3 1.4 1 0 0 1 1 1 0 Mnd1 family Hce2 PF14856.1 EAQ84442.1 - 0.00028 20.7 0.1 0.00059 19.7 0.0 1.6 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Methyltransf_18 PF12847.2 EAQ84443.1 - 1.3e-06 28.9 0.1 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84443.1 - 3e-05 24.4 0.0 7.8e-05 23.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ84443.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84443.1 - 0.00037 20.9 0.0 0.0011 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAQ84443.1 - 0.0014 18.0 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EAQ84443.1 - 0.0021 18.0 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ84443.1 - 0.0024 17.0 0.0 0.0051 15.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family 3HCDH_N PF02737.13 EAQ84443.1 - 0.011 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EAQ84443.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.7 EAQ84443.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 EAQ84443.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ84443.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EAQ84443.1 - 0.07 12.6 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EAQ84443.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_6 PF14259.1 EAQ84444.1 - 1.6e-44 149.6 0.1 7.9e-16 57.7 0.0 5.0 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ84444.1 - 3.2e-44 148.4 0.0 1.4e-15 56.6 0.0 5.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ84444.1 - 1.3e-20 72.9 0.0 3.1e-08 33.3 0.0 5.2 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EAQ84444.1 - 0.0026 17.1 0.8 0.0092 15.3 0.5 2.0 1 0 0 1 1 1 1 Lsm interaction motif RRM_3 PF08777.6 EAQ84444.1 - 0.0059 16.4 0.0 0.0059 16.4 0.0 3.7 5 0 0 5 5 5 1 RNA binding motif Serglycin PF04360.7 EAQ84444.1 - 0.015 15.0 1.3 0.033 13.9 0.9 1.5 1 0 0 1 1 1 0 Serglycin DUF3467 PF11950.3 EAQ84444.1 - 0.038 13.9 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) F-box PF00646.28 EAQ84447.1 - 0.0036 16.9 0.2 0.0082 15.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAQ84447.1 - 0.03 14.0 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Peroxidase_2 PF01328.12 EAQ84448.1 - 2.7e-42 144.5 0.1 3.4e-42 144.2 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Ribonuclease_T2 PF00445.13 EAQ84448.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease T2 family Fungal_trans_2 PF11951.3 EAQ84449.1 - 5.8e-07 28.4 0.5 8.4e-07 27.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRF PF01765.14 EAQ84449.1 - 0.00058 19.3 0.2 0.00093 18.7 0.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor IncA PF04156.9 EAQ84449.1 - 0.011 15.3 0.0 0.011 15.3 0.0 2.4 3 0 0 3 3 3 0 IncA protein DUF1418 PF07214.7 EAQ84449.1 - 0.42 10.2 3.0 0.4 10.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Cnd1_N PF12922.2 EAQ84450.1 - 0.056 13.0 1.0 0.099 12.2 0.7 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term adh_short PF00106.20 EAQ84451.1 - 2.3e-07 30.8 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ84451.1 - 8.6e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ84451.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lipase_GDSL_2 PF13472.1 EAQ84453.1 - 3.9e-13 49.9 0.2 4.8e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ84453.1 - 1.5e-11 44.5 0.0 1.8e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EAQ84453.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family RRM_DME PF15628.1 EAQ84453.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RRM in Demeter CN_hydrolase PF00795.17 EAQ84454.1 - 1.5e-14 53.7 0.0 1.8e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_transf_49 PF13896.1 EAQ84454.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan STE2 PF02116.10 EAQ84455.1 - 7.5e-23 80.9 11.4 7.5e-23 80.9 7.9 1.4 1 1 1 2 2 2 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 EAQ84457.1 - 3.3e-33 113.9 0.1 5.5e-33 113.2 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EAQ84457.1 - 1.2e-23 82.4 0.0 1.2e-23 82.4 0.0 1.7 2 0 0 2 2 2 1 Vps23 core domain TFIIA PF03153.8 EAQ84457.1 - 0.86 9.4 15.4 1.2 8.9 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IDO PF01231.13 EAQ84458.1 - 8.7e-170 564.7 0.0 1e-169 564.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Glyco_hydro_7 PF00840.15 EAQ84461.1 - 4.1e-135 450.4 4.1 9.6e-134 445.9 2.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 COesterase PF00135.23 EAQ84464.1 - 1.3e-81 274.9 0.0 7.7e-81 272.4 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ84464.1 - 3.3e-05 23.5 0.0 0.00041 19.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EAQ84465.1 - 2.2e-25 89.1 35.4 8.3e-23 80.6 17.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EAQ84466.1 - 4.2e-18 65.1 0.0 3.8e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.9 EAQ84467.1 - 7.7e-58 195.8 0.1 1.1e-57 195.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ84467.1 - 6.2e-12 44.9 13.1 2.1e-11 43.2 9.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain RVT_1 PF00078.22 EAQ84468.1 - 3.3e-11 42.9 0.0 5.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.2 EAQ84468.1 - 0.00063 19.4 3.0 0.00094 18.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAQ84468.1 - 0.0034 17.0 0.1 0.0098 15.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain zf-RVT PF13966.1 EAQ84468.1 - 0.057 13.7 0.3 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase MFS_1 PF07690.11 EAQ84469.1 - 8.4e-39 133.2 52.1 2.4e-38 131.7 32.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ84469.1 - 1.4e-13 50.2 15.3 4.4e-13 48.6 10.6 1.7 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EAQ84470.1 - 0.0093 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAQ84470.1 - 0.054 13.2 0.1 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ84470.1 - 0.057 12.9 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4413 PF14372.1 EAQ84471.1 - 0.00022 21.1 0.5 0.46 10.4 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4413) zf-BED PF02892.10 EAQ84471.1 - 0.00039 20.1 0.4 0.00072 19.2 0.3 1.5 1 0 0 1 1 1 1 BED zinc finger DUF4174 PF13778.1 EAQ84471.1 - 0.022 14.8 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) NmrA PF05368.8 EAQ84475.1 - 2.1e-37 128.6 0.0 2.7e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ84475.1 - 6.1e-10 39.3 0.5 1.2e-09 38.4 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ84475.1 - 8.1e-06 24.7 0.0 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ84475.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAQ84475.1 - 0.0069 16.3 0.4 0.0069 16.3 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EAQ84475.1 - 0.0083 16.4 0.1 0.021 15.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EAQ84475.1 - 0.049 13.5 0.3 0.2 11.5 0.0 2.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Peptidase_S28 PF05577.7 EAQ84476.1 - 4e-31 108.0 0.0 4.8e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EAQ84476.1 - 0.00032 20.6 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_5 PF00266.14 EAQ84477.1 - 9.9e-33 113.3 0.0 1e-21 77.1 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Matrilin_ccoil PF10393.4 EAQ84478.1 - 0.086 12.2 0.3 11 5.4 0.1 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ADH_N PF08240.7 EAQ84479.1 - 7.3e-20 70.7 0.0 2.1e-19 69.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ84479.1 - 1.3e-06 27.9 0.1 1.9e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EAQ84479.1 - 0.00028 20.4 2.4 0.00028 20.4 1.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EAQ84479.1 - 0.014 13.9 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_11 PF08241.7 EAQ84479.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 EAQ84481.1 - 6.4e-73 245.8 16.7 8.6e-73 245.4 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84481.1 - 1.6e-26 92.8 29.6 2.2e-26 92.4 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UPF0075 PF03702.9 EAQ84482.1 - 2.5e-83 280.0 0.0 3e-83 279.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Fungal_trans PF04082.13 EAQ84483.1 - 8e-07 28.1 2.1 1.2e-06 27.6 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_ser-thr_kin PF05445.6 EAQ84483.1 - 0.12 11.1 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EAQ84484.1 - 1.2e-08 34.4 0.0 1.3e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84484.1 - 1.7e-06 27.3 0.0 2.1e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase YTH PF04146.10 EAQ84485.1 - 2.9e-30 104.7 0.0 4e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain Pkinase PF00069.20 EAQ84485.1 - 3.4e-13 49.3 0.0 4.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Fer4_5 PF12801.2 EAQ84485.1 - 0.68 9.7 3.2 5.3 6.9 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fungal_lectin PF07938.7 EAQ84487.1 - 7.8e-25 87.8 9.2 2.5e-24 86.1 6.4 1.7 1 1 0 1 1 1 1 Fungal fucose-specific lectin DUF1996 PF09362.5 EAQ84489.1 - 8.1e-88 294.0 1.1 9.8e-88 293.7 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4149 PF13664.1 EAQ84490.1 - 7.9e-18 64.3 2.3 1.7e-17 63.3 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) F-box PF00646.28 EAQ84490.1 - 0.00047 19.7 0.0 0.0016 18.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain CTNNBL PF08216.6 EAQ84491.1 - 5.3e-35 119.2 0.0 6.2e-34 115.8 0.0 2.5 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EAQ84491.1 - 0.056 13.2 0.3 0.33 10.8 0.0 2.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAQ84491.1 - 0.069 13.4 3.2 0.6 10.4 0.3 3.2 2 0 0 2 2 2 0 HEAT repeats V-ATPase_G PF03179.10 EAQ84492.1 - 1.2e-24 86.6 16.0 1.3e-24 86.4 11.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YlqD PF11068.3 EAQ84492.1 - 0.048 13.7 5.5 0.06 13.3 3.8 1.3 1 0 0 1 1 1 0 YlqD protein DUF2203 PF09969.4 EAQ84492.1 - 0.089 13.0 5.2 0.1 12.7 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Striatin PF08232.7 EAQ84492.1 - 0.18 12.1 7.7 0.22 11.8 5.3 1.1 1 0 0 1 1 1 0 Striatin family YusW PF14039.1 EAQ84492.1 - 0.43 10.8 7.6 0.46 10.7 4.7 1.5 1 1 1 2 2 2 0 YusW-like protein Asp-B-Hydro_N PF05279.6 EAQ84492.1 - 0.52 10.1 11.0 0.59 9.9 7.6 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RRF PF01765.14 EAQ84492.1 - 0.58 9.6 12.3 0.71 9.3 8.5 1.1 1 0 0 1 1 1 0 Ribosome recycling factor FbpA PF05833.6 EAQ84492.1 - 0.84 8.0 9.7 1 7.7 6.7 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) OmpH PF03938.9 EAQ84492.1 - 1 9.2 10.8 1.2 9.0 7.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GARS_C PF02843.11 EAQ84492.1 - 2 8.6 4.4 23 5.2 2.6 2.3 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Vfa1 PF08432.5 EAQ84492.1 - 2.1 8.3 11.3 2.3 8.1 7.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 EAQ84492.1 - 3.1 6.6 8.1 3.4 6.5 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 EAQ84492.1 - 3.1 7.6 20.1 8.6 6.1 7.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DDRGK PF09756.4 EAQ84492.1 - 3.1 7.1 16.7 3.8 6.8 11.6 1.1 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.7 EAQ84492.1 - 3.6 7.3 9.7 4.1 7.2 6.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GvpL_GvpF PF06386.6 EAQ84492.1 - 3.9 7.0 8.6 5.3 6.5 6.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ribosomal_L37 PF08561.5 EAQ84492.1 - 4 7.0 11.6 1.4 8.5 1.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Spore_coat_CotO PF14153.1 EAQ84492.1 - 4.6 6.6 11.7 5 6.5 8.1 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Atg14 PF10186.4 EAQ84492.1 - 5.1 5.9 7.7 5.8 5.7 5.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3987 PF13148.1 EAQ84492.1 - 6.4 5.2 12.4 7.2 5.0 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF883 PF05957.8 EAQ84492.1 - 7.8 6.9 11.5 7.9 6.9 4.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RNA_pol_Rpb2_6 PF00562.23 EAQ84493.1 - 1.3e-125 419.1 0.1 2.4e-125 418.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 EAQ84493.1 - 6.9e-46 156.0 0.0 2.8e-45 154.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.10 EAQ84493.1 - 1.2e-36 125.6 0.0 6.4e-33 113.3 0.0 2.3 1 1 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_5 PF04567.12 EAQ84493.1 - 3e-25 87.9 0.0 8.5e-25 86.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EAQ84493.1 - 5.9e-23 80.4 0.0 1.7e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EAQ84493.1 - 2.4e-20 72.1 0.2 6.9e-20 70.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.15 EAQ84493.1 - 7.1e-19 67.8 0.0 1.7e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Glyco_hydro_45 PF02015.11 EAQ84495.1 - 2.3e-89 298.7 13.9 2.3e-89 298.7 9.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EAQ84495.1 - 2.6e-10 39.7 18.7 2.6e-10 39.7 13.0 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Neisseria_TspB PF05616.8 EAQ84495.1 - 0.023 13.0 6.3 0.029 12.7 4.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NAD_binding_2 PF03446.10 EAQ84498.1 - 3.1e-09 36.8 0.0 4.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EAQ84498.1 - 0.00032 21.0 0.1 0.00086 19.6 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EAQ84498.1 - 0.0048 17.0 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EAQ84498.1 - 0.014 15.1 0.1 0.035 13.8 0.1 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus COesterase PF00135.23 EAQ84499.1 - 5.2e-47 160.7 0.0 1.2e-36 126.5 0.0 3.3 2 2 1 3 3 3 3 Carboxylesterase family Pox_I5 PF04713.7 EAQ84500.1 - 3.3 7.4 7.7 2.4 7.9 0.4 3.0 3 1 0 3 3 3 0 Poxvirus protein I5 CorA PF01544.13 EAQ84503.1 - 1.8e-09 37.0 0.3 2.7e-09 36.4 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SLAC1 PF03595.12 EAQ84503.1 - 0.015 13.9 0.5 0.022 13.4 0.3 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel DctQ PF04290.7 EAQ84504.1 - 2.4 7.9 14.1 0.16 11.6 1.3 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Pectate_lyase PF03211.8 EAQ84505.1 - 2.3e-80 269.0 6.5 3.2e-80 268.5 4.5 1.1 1 0 0 1 1 1 1 Pectate lyase DUF3362 PF11842.3 EAQ84506.1 - 0.0017 18.3 1.1 0.049 13.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3362) BTB PF00651.26 EAQ84507.1 - 7.3e-06 25.9 0.0 5.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.1 EAQ84508.1 - 0.16 12.3 5.5 0.68 10.3 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger RVT_1 PF00078.22 EAQ84509.1 - 4.9e-32 111.0 0.0 9.9e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84509.1 - 3e-22 78.4 0.0 3.7e-21 74.9 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84509.1 - 5.1e-09 36.4 0.1 1.1e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Trypsin_2 PF13365.1 EAQ84510.1 - 4.9e-15 55.5 0.0 1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Beta-lactamase PF00144.19 EAQ84511.1 - 4.1e-32 111.5 2.6 7.3e-32 110.6 1.8 1.3 1 0 0 1 1 1 1 Beta-lactamase DNase_NucA_NucB PF14040.1 EAQ84511.1 - 1.1e-07 31.9 0.1 2.9e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Chorismate_bind PF00425.13 EAQ84512.1 - 1.9e-77 260.0 0.2 1.4e-74 250.6 0.0 3.5 3 1 0 3 3 3 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EAQ84512.1 - 3.1e-24 85.5 0.1 6.4e-21 74.8 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region CITED PF04487.7 EAQ84512.1 - 0.023 14.9 0.0 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 CITED Amidase PF01425.16 EAQ84513.1 - 2.1e-29 102.6 0.1 3.8e-29 101.8 0.1 1.4 1 1 0 1 1 1 1 Amidase Glyco_hydro_88 PF07470.8 EAQ84515.1 - 3.7e-75 253.0 0.2 4.2e-75 252.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 EAQ84516.1 - 6e-21 74.5 12.8 6e-21 74.5 8.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EAQ84516.1 - 2.3 7.7 5.2 14 5.2 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) DUF3433 PF11915.3 EAQ84517.1 - 1.8e-27 95.3 16.0 7.5e-16 58.0 0.3 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) HSP70 PF00012.15 EAQ84517.1 - 4.9e-09 34.6 0.0 7.4e-09 34.0 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ84517.1 - 0.0027 16.3 0.0 0.0069 15.0 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein ADIP PF11559.3 EAQ84518.1 - 0.0023 17.8 1.9 0.0072 16.2 1.3 1.8 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Striatin PF08232.7 EAQ84518.1 - 0.16 12.2 2.2 0.32 11.3 1.5 1.5 1 0 0 1 1 1 0 Striatin family Zwint PF15556.1 EAQ84518.1 - 0.26 10.4 6.2 0.071 12.3 1.7 1.9 2 0 0 2 2 2 0 ZW10 interactor FAD_binding_4 PF01565.18 EAQ84519.1 - 1.3e-23 82.9 0.9 2.5e-23 82.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_4 PF13894.1 EAQ84520.1 - 1.2 9.6 7.0 24 5.5 1.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Exo_endo_phos_2 PF14529.1 EAQ84521.1 - 8e-17 60.9 0.0 2.3e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84521.1 - 3.9e-08 33.5 0.1 9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPOB_a PF14689.1 EAQ84521.1 - 0.031 13.8 0.4 0.086 12.4 0.3 1.7 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain MAGE_N PF12440.3 EAQ84521.1 - 0.052 13.8 2.5 9 6.6 2.4 2.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF1640 PF07798.6 EAQ84521.1 - 0.38 10.7 7.4 0.76 9.8 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Prominin PF05478.6 EAQ84521.1 - 3.5 5.0 5.6 0.59 7.5 1.4 1.4 2 0 0 2 2 2 0 Prominin Baculo_PEP_C PF04513.7 EAQ84521.1 - 7.3 6.4 8.4 1.2 9.0 2.8 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_lectin PF07938.7 EAQ84523.1 - 1.6e-05 24.4 0.0 4.5e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Fungal fucose-specific lectin FAM212 PF15342.1 EAQ84523.1 - 0.00023 20.7 0.3 0.0041 16.6 0.1 2.4 2 0 0 2 2 2 1 FAM212 family UvrD_C_2 PF13538.1 EAQ84524.1 - 0.00013 22.0 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EAQ84524.1 - 0.0055 15.7 0.1 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.22 EAQ84525.1 - 2.7e-42 144.3 0.0 6.5e-20 71.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAQ84525.1 - 3.8e-15 56.6 0.0 0.0023 17.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EAQ84525.1 - 1.4e-10 40.7 1.2 0.01 15.0 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAQ84525.1 - 3.7e-08 32.7 0.7 0.003 17.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EAQ84525.1 - 3.3e-07 29.9 0.0 0.018 14.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EAQ84525.1 - 1e-06 28.9 1.2 0.049 13.6 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EAQ84525.1 - 2.3e-06 28.3 0.0 0.14 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAQ84525.1 - 2.4e-06 27.7 0.1 0.11 12.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EAQ84525.1 - 7e-06 25.6 0.1 0.051 13.0 0.1 2.6 2 0 0 2 2 2 2 AAA-like domain MMR_HSR1 PF01926.18 EAQ84525.1 - 9.5e-06 25.5 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 EAQ84525.1 - 1.2e-05 25.2 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAQ84525.1 - 1.3e-05 24.4 0.0 0.044 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EAQ84525.1 - 3e-05 24.4 0.0 0.073 13.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein cobW PF02492.14 EAQ84525.1 - 0.0001 21.8 0.1 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EAQ84525.1 - 0.00014 21.4 0.0 0.073 12.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EAQ84525.1 - 0.0002 21.0 1.8 1 9.0 0.0 3.5 2 1 1 3 3 3 2 NACHT domain MobB PF03205.9 EAQ84525.1 - 0.00023 20.8 0.6 0.72 9.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EAQ84525.1 - 0.00036 20.3 1.1 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EAQ84525.1 - 0.00061 19.6 2.5 0.064 13.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EAQ84525.1 - 0.00088 19.0 0.0 0.21 11.2 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 EAQ84525.1 - 0.0011 19.2 0.0 2.4 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EAQ84525.1 - 0.0014 17.5 0.1 0.059 12.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.1 EAQ84525.1 - 0.0022 17.5 0.1 0.085 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EAQ84525.1 - 0.0023 18.2 4.7 0.11 12.7 0.1 2.5 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EAQ84525.1 - 0.0028 17.8 0.0 1.2 9.3 0.0 2.9 4 0 0 4 4 2 1 RNA helicase AAA_19 PF13245.1 EAQ84525.1 - 0.006 16.3 0.1 0.27 11.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EAQ84525.1 - 0.0096 15.0 0.1 0.89 8.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin GTP_EFTU PF00009.22 EAQ84525.1 - 0.021 14.2 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EAQ84525.1 - 0.033 13.7 0.2 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EAQ84525.1 - 0.034 13.8 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EAQ84525.1 - 0.035 13.6 0.0 4.1 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EAQ84525.1 - 0.048 13.5 0.0 9 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EAQ84525.1 - 0.057 12.4 0.0 3 6.7 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain DUF3987 PF13148.1 EAQ84525.1 - 0.09 11.3 6.2 0.11 11.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3987) SbcCD_C PF13558.1 EAQ84525.1 - 0.095 12.6 0.4 2 8.3 0.1 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EAQ84525.1 - 0.12 11.1 0.1 3.6 6.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.10 EAQ84525.1 - 0.18 10.4 0.4 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Pox_A32 PF04665.7 EAQ84525.1 - 0.19 10.9 0.2 10 5.2 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein DUF815 PF05673.8 EAQ84525.1 - 0.25 10.2 0.2 15 4.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AMP-binding PF00501.23 EAQ84526.1 - 0 1221.3 0.1 3.5e-82 276.0 0.0 6.4 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 EAQ84526.1 - 0 1034.4 0.0 1.6e-42 145.4 0.0 10.4 9 2 0 9 9 9 9 Condensation domain PP-binding PF00550.20 EAQ84526.1 - 1.1e-75 249.8 0.0 1.1e-15 57.6 0.0 7.9 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ84526.1 - 3.3e-22 79.2 5.3 0.00023 22.0 0.0 6.0 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EAQ84526.1 - 4e-08 33.4 2.3 0.019 15.2 0.0 5.6 5 0 0 5 5 5 1 HxxPF-repeated domain Transferase PF02458.10 EAQ84526.1 - 1.7e-06 26.7 0.0 0.22 9.9 0.0 5.2 5 0 0 5 5 5 1 Transferase family AATase PF07247.7 EAQ84526.1 - 2.8 6.3 0.1 44 2.4 0.0 2.9 4 0 0 4 4 4 0 Alcohol acetyltransferase Na_trans_assoc PF06512.8 EAQ84526.1 - 9.7 6.0 0.0 19 5.1 0.0 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated CorA PF01544.13 EAQ84527.1 - 2e-11 43.5 0.1 3.3e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA PF00004.24 EAQ84528.1 - 2.7e-06 27.5 0.0 8.7e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CesT PF05932.8 EAQ84528.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family MARVEL PF01284.18 EAQ84530.1 - 0.00016 21.5 6.5 0.00023 21.0 4.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain CBM_1 PF00734.13 EAQ84531.1 - 3.3e-08 33.0 14.7 3.3e-08 33.0 10.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 EAQ84531.1 - 1.6e-06 27.8 0.2 2.8e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Toxin_7 PF05980.7 EAQ84531.1 - 0.0064 16.4 10.7 0.012 15.6 7.4 1.5 1 0 0 1 1 1 1 Toxin 7 TPR_10 PF13374.1 EAQ84532.1 - 1.2e-11 44.0 3.5 0.013 15.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ84532.1 - 2.2e-10 40.3 4.3 1.3e-05 25.0 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ84532.1 - 0.05 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.1 EAQ84532.1 - 0.052 14.0 0.4 1.1 9.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ84532.1 - 0.059 13.3 0.2 1.2 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EAQ84533.1 - 2.9e-89 299.7 31.8 3.6e-89 299.4 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84533.1 - 1.7e-26 92.7 26.0 1.7e-26 92.7 18.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 EAQ84534.1 - 6.5e-50 169.8 0.7 8.4e-50 169.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pec_lyase_C PF00544.14 EAQ84535.1 - 8e-29 100.5 5.9 1e-28 100.2 4.1 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EAQ84535.1 - 2.2e-06 27.5 31.6 4.9e-05 23.1 5.6 2.3 1 1 2 3 3 3 3 Right handed beta helix region Profilin PF00235.14 EAQ84535.1 - 0.05 13.7 0.2 0.33 11.0 0.0 2.1 1 1 1 2 2 2 0 Profilin CBM_X2 PF03442.9 EAQ84535.1 - 0.57 10.0 2.7 1.1 9.1 0.1 2.5 2 1 0 2 2 2 0 Carbohydrate binding domain X2 Pec_lyase_C PF00544.14 EAQ84536.1 - 7.6e-24 84.2 2.3 8.9e-24 84.0 1.0 1.6 2 1 0 2 2 2 1 Pectate lyase Beta_helix PF13229.1 EAQ84536.1 - 0.0006 19.6 13.6 0.028 14.1 5.7 2.5 1 1 1 2 2 2 2 Right handed beta helix region Pectinesterase PF01095.14 EAQ84537.1 - 1.7e-25 89.2 7.6 2.7e-12 45.8 3.5 2.1 1 1 1 2 2 2 2 Pectinesterase TIL PF01826.12 EAQ84538.1 - 0.1 12.7 2.8 1.8 8.7 2.0 2.0 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Fer4_6 PF12837.2 EAQ84538.1 - 3.3 7.7 8.4 5.2 7.0 0.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Pro-kuma_activ PF09286.6 EAQ84539.1 - 6.2e-26 91.1 0.0 1.8e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain TmoB PF06234.7 EAQ84540.1 - 0.027 14.3 0.3 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Ank_2 PF12796.2 EAQ84541.1 - 2.7e-52 175.0 6.3 6.6e-15 55.2 0.2 7.3 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84541.1 - 9e-36 119.9 19.8 6.3e-07 28.8 0.3 12.2 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 EAQ84541.1 - 2.4e-33 113.8 8.6 5.6e-06 26.7 0.0 8.2 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ84541.1 - 4.3e-33 112.5 19.4 2.4e-08 33.9 0.0 10.7 7 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84541.1 - 6.7e-28 93.9 6.7 0.0003 20.7 0.0 11.5 13 0 0 13 13 11 7 Ankyrin repeat AAA_16 PF13191.1 EAQ84541.1 - 3.1e-09 37.0 0.0 3.1e-09 37.0 0.0 2.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 EAQ84541.1 - 0.00085 19.0 0.1 0.003 17.2 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EAQ84541.1 - 0.0027 17.3 0.0 0.011 15.3 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EAQ84541.1 - 0.0058 16.7 0.1 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ84541.1 - 0.0064 15.9 0.1 0.027 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EAQ84541.1 - 0.15 11.0 0.0 1.1 8.1 0.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain RNA12 PF10443.4 EAQ84541.1 - 0.16 10.4 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein NACHT PF05729.7 EAQ84544.1 - 1.9e-07 30.8 0.1 8e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EAQ84544.1 - 8e-07 29.2 0.0 5.5e-06 26.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EAQ84544.1 - 0.00012 22.1 0.0 0.00094 19.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EAQ84544.1 - 0.0052 17.0 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAQ84544.1 - 0.0056 16.1 0.2 0.018 14.4 0.0 2.0 2 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EAQ84544.1 - 0.0066 16.7 0.4 0.027 14.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 EAQ84544.1 - 0.0071 17.1 0.0 0.024 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAQ84544.1 - 0.01 15.3 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EAQ84544.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 EAQ84544.1 - 0.014 15.0 0.0 0.09 12.5 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 EAQ84544.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EAQ84544.1 - 0.015 15.1 0.0 0.049 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EAQ84544.1 - 0.025 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EAQ84544.1 - 0.036 13.7 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EAQ84544.1 - 0.038 14.1 0.1 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EAQ84544.1 - 0.056 12.8 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EAQ84544.1 - 0.074 12.7 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EAQ84544.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArgK PF03308.11 EAQ84544.1 - 0.08 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 EAQ84544.1 - 0.14 12.6 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Parvo_NS1 PF01057.12 EAQ84544.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF258 PF03193.11 EAQ84544.1 - 0.18 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3667 PF12412.3 EAQ84548.1 - 0.037 13.3 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) Copper-fist PF00649.13 EAQ84553.1 - 0.011 14.8 0.3 0.02 14.0 0.2 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain PIF1 PF05970.9 EAQ84557.1 - 3.5e-29 101.8 0.0 1.1e-22 80.5 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ84557.1 - 2.7e-09 36.8 0.0 8.2e-08 32.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ84557.1 - 7.4e-05 22.4 0.1 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ84557.1 - 0.00049 17.9 0.0 0.00097 17.0 0.0 1.4 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EAQ84557.1 - 0.0043 17.1 0.0 0.029 14.5 0.0 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EAQ84557.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAQ84557.1 - 0.083 12.4 0.2 7.7 5.9 0.0 2.8 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EAQ84557.1 - 0.14 11.7 0.1 1.4 8.4 0.0 2.3 1 1 0 2 2 2 0 AAA domain Torsin PF06309.6 EAQ84557.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Torsin Glyco_hydro_10 PF00331.15 EAQ84558.1 - 2.1e-102 342.4 0.4 2.5e-102 342.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 LepA_C PF06421.7 EAQ84559.1 - 8.5e-40 135.0 4.0 1.4e-39 134.2 2.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 EAQ84559.1 - 4.2e-36 124.1 0.0 7.2e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAQ84559.1 - 1.2e-17 63.5 0.0 2.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EAQ84559.1 - 5e-06 26.5 0.2 1e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EAQ84559.1 - 9e-06 25.4 0.0 8.8e-05 22.2 0.0 2.5 2 1 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.17 EAQ84559.1 - 0.00041 19.7 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EAQ84559.1 - 0.11 11.7 0.1 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MIT PF04212.13 EAQ84560.1 - 3.9e-11 42.6 0.3 8.4e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF2268 PF10026.4 EAQ84560.1 - 0.36 10.1 0.1 0.63 9.3 0.1 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Dimer_Tnp_hAT PF05699.9 EAQ84561.1 - 1.4e-16 59.8 0.2 1.4e-16 59.8 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RVT_1 PF00078.22 EAQ84562.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_25 PF01755.12 EAQ84563.1 - 5.5e-11 42.4 0.0 4.2e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Yae1_N PF09811.4 EAQ84565.1 - 2.1e-05 23.9 2.5 4.8e-05 22.7 1.8 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal EBV-NA3 PF05009.7 EAQ84565.1 - 0.11 11.7 0.1 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Mfp-3 PF04202.8 EAQ84565.1 - 0.15 12.2 1.9 0.23 11.6 1.3 1.4 1 0 0 1 1 1 0 Foot protein 3 CAP59_mtransfer PF11735.3 EAQ84568.1 - 1.7e-66 223.9 0.0 2.1e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Na_Ca_ex PF01699.19 EAQ84569.1 - 3.3e-26 91.5 19.1 4.1e-16 58.8 2.8 2.8 2 2 1 3 3 3 2 Sodium/calcium exchanger protein Zip PF02535.17 EAQ84569.1 - 0.062 12.3 7.3 3 6.7 5.0 2.4 1 1 0 1 1 1 0 ZIP Zinc transporter DUF4173 PF13777.1 EAQ84569.1 - 0.063 12.5 0.2 0.063 12.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) CAP59_mtransfer PF11735.3 EAQ84571.1 - 7.5e-09 35.1 0.0 1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_hydro_18 PF00704.23 EAQ84573.1 - 1.2e-78 264.9 4.7 1.7e-78 264.4 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EAQ84573.1 - 1.3e-07 31.4 15.4 1.3e-07 31.4 10.7 4.6 4 0 0 4 4 4 1 Chitin recognition protein LysM PF01476.15 EAQ84574.1 - 1e-25 89.3 1.4 0.025 14.4 0.0 7.9 8 0 0 8 8 8 7 LysM domain DUF3487 PF11990.3 EAQ84574.1 - 0.0038 16.6 0.0 3.1 7.2 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF3487) HTH_Tnp_1 PF01527.15 EAQ84574.1 - 0.03 14.2 0.0 41 4.2 0.0 4.0 4 0 0 4 4 4 0 Transposase DUF4286 PF14114.1 EAQ84576.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Glyco_hydro_6 PF01341.12 EAQ84577.1 - 5.8e-89 298.4 1.0 6.8e-89 298.2 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EAQ84577.1 - 4.3e-10 39.0 13.3 4.3e-10 39.0 9.2 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAQ84577.1 - 0.067 13.2 7.3 0.14 12.1 5.0 1.6 1 0 0 1 1 1 0 Toxin 7 Barwin PF00967.12 EAQ84578.1 - 0.16 11.6 0.3 0.25 11.0 0.1 1.3 1 1 0 1 1 1 0 Barwin family RVT_1 PF00078.22 EAQ84580.1 - 2.7e-40 137.9 0.0 3.9e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 EAQ84581.1 - 1.1e-06 28.0 0.0 2e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84581.1 - 0.00045 19.3 0.0 0.082 11.9 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase p450 PF00067.17 EAQ84582.1 - 3.5e-09 35.7 0.0 3.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Pkinase PF00069.20 EAQ84583.1 - 2.6e-07 30.0 0.0 5.5e-06 25.7 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain DUF4246 PF14033.1 EAQ84583.1 - 0.28 9.7 9.1 0.38 9.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) CDC45 PF02724.9 EAQ84583.1 - 1.3 6.9 14.0 1.8 6.5 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Mnd1 PF03962.10 EAQ84583.1 - 6.1 6.4 23.0 10 5.7 15.9 1.3 1 0 0 1 1 1 0 Mnd1 family Daxx PF03344.10 EAQ84583.1 - 6.6 5.0 21.8 9.3 4.5 15.1 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EAQ84583.1 - 7.7 4.0 14.8 10 3.6 10.2 1.1 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 EAQ84583.1 - 8.4 5.2 13.0 13 4.6 9.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Aldo_ket_red PF00248.16 EAQ84585.1 - 1.6e-29 102.6 0.0 3.5e-15 55.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family HET PF06985.6 EAQ84586.1 - 9.9e-09 35.4 1.7 6.8e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Amidoligase_2 PF12224.3 EAQ84589.1 - 1.6e-11 44.3 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme MFS_1 PF07690.11 EAQ84590.1 - 8.3e-14 51.0 48.1 8.3e-14 51.0 33.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4662 PF15578.1 EAQ84591.1 - 0.11 12.0 0.1 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) COesterase PF00135.23 EAQ84592.1 - 4.2e-72 243.5 0.0 5.2e-67 226.7 0.0 2.1 1 1 0 2 2 2 2 Carboxylesterase family Ank_2 PF12796.2 EAQ84592.1 - 2.2e-14 53.5 0.0 4.8e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84592.1 - 3.6e-12 45.4 4.6 6.5e-05 22.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EAQ84592.1 - 1.6e-11 44.0 0.1 2.9e-07 30.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ84592.1 - 4.2e-09 36.6 0.0 2.1e-06 28.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84592.1 - 7.1e-09 35.0 0.0 0.072 13.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Abhydrolase_3 PF07859.8 EAQ84592.1 - 1.2e-06 28.2 0.1 2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ84592.1 - 0.00012 21.8 0.5 0.00022 21.0 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ84592.1 - 0.00026 20.9 1.8 0.00032 20.6 0.3 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ84592.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LIP PF03583.9 EAQ84592.1 - 0.22 10.6 0.4 0.52 9.4 0.1 1.6 2 0 0 2 2 2 0 Secretory lipase TIG PF01833.19 EAQ84597.1 - 0.071 13.1 1.9 0.36 10.8 1.3 2.2 1 0 0 1 1 1 0 IPT/TIG domain DUF4419 PF14388.1 EAQ84603.1 - 8.5e-91 304.2 0.0 1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) IlvB_leader PF08049.6 EAQ84603.1 - 5.8 6.7 5.5 2.3 8.0 1.8 1.9 2 0 0 2 2 2 0 IlvB leader peptide Peptidase_S8 PF00082.17 EAQ84604.1 - 8.1e-11 41.5 0.9 1.4e-10 40.8 0.6 1.3 1 0 0 1 1 1 1 Subtilase family LBP_BPI_CETP PF01273.20 EAQ84605.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.4 1 1 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Glyco_hydro_61 PF03443.9 EAQ84607.1 - 9.9e-16 58.2 0.0 1.1e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_N PF00732.14 EAQ84608.1 - 3e-20 72.5 0.0 8.7e-20 71.0 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ84608.1 - 6.2e-19 68.7 0.1 1.2e-18 67.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAQ84608.1 - 1.1e-09 37.6 0.4 0.00018 20.4 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EAQ84608.1 - 2.1e-07 30.1 0.0 2.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ84608.1 - 6e-05 22.9 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ84608.1 - 0.0003 20.7 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 EAQ84608.1 - 0.00045 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.9 EAQ84608.1 - 0.00091 17.8 0.1 0.0013 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EAQ84608.1 - 0.0068 16.7 0.1 0.073 13.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ84608.1 - 0.0074 15.4 0.0 0.14 11.1 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ84608.1 - 0.0076 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ84608.1 - 0.009 15.1 0.1 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EAQ84608.1 - 0.047 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EAQ84608.1 - 0.049 12.6 0.1 0.13 11.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EAQ84608.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EAQ84608.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF605 PF04652.11 EAQ84609.1 - 0.23 10.8 12.9 0.43 9.9 9.0 1.4 1 0 0 1 1 1 0 Vta1 like Dimer_Tnp_hAT PF05699.9 EAQ84610.1 - 8.9e-06 25.2 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exo_endo_phos_2 PF14529.1 EAQ84612.1 - 1e-17 63.8 1.0 1.1e-16 60.4 0.1 2.8 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84612.1 - 0.00091 19.2 0.2 0.0041 17.0 0.1 2.1 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EAQ84612.1 - 0.01 15.7 2.7 0.01 15.7 1.9 2.3 2 0 0 2 2 2 0 Zinc knuckle PurS PF02700.9 EAQ84612.1 - 0.042 13.8 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF948 PF06103.6 EAQ84612.1 - 0.055 13.3 0.9 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SEEK1 PF15357.1 EAQ84612.1 - 0.069 13.0 0.5 0.18 11.6 0.3 1.7 2 0 0 2 2 2 0 Psoriasis susceptibility 1 candidate 1 SlyX PF04102.7 EAQ84612.1 - 0.073 13.4 6.6 0.12 12.7 3.3 2.2 1 1 1 2 2 2 0 SlyX Phage_lysis PF03245.8 EAQ84612.1 - 1.5 8.7 7.9 0.13 12.2 0.6 2.5 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein ADIP PF11559.3 EAQ84612.1 - 5.4 6.8 9.8 0.37 10.7 2.7 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Acetyltransf_13 PF13880.1 EAQ84613.1 - 0.074 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RNA_pol_Rpb1_5 PF04998.12 EAQ84614.1 - 2e-68 230.6 0.0 3.2e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EAQ84614.1 - 1.8e-67 226.4 0.0 4.5e-67 225.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EAQ84614.1 - 2.4e-45 155.2 0.0 7.7e-42 143.7 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EAQ84614.1 - 5.3e-36 123.7 0.0 2.1e-35 121.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EAQ84614.1 - 1.5e-32 111.5 0.1 6.7e-32 109.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DDHD PF02862.12 EAQ84615.1 - 2.5e-74 249.8 9.2 7.8e-74 248.2 0.0 3.5 2 2 0 2 2 2 1 DDHD domain DUF2305 PF10230.4 EAQ84615.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) zf-RING_2 PF13639.1 EAQ84616.1 - 0.0037 17.0 9.4 0.0093 15.7 6.5 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ84616.1 - 0.013 15.5 3.1 0.013 15.5 2.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ84616.1 - 0.015 15.1 3.4 0.034 14.0 2.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.2 EAQ84616.1 - 0.022 15.0 0.1 0.056 13.7 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) zf-RING_UBOX PF13445.1 EAQ84616.1 - 0.032 13.9 0.3 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EAQ84616.1 - 0.044 13.5 4.2 0.076 12.7 2.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EAQ84616.1 - 0.047 13.2 0.5 0.047 13.2 0.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EAQ84616.1 - 0.14 12.0 0.7 0.26 11.1 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EAQ84616.1 - 0.18 11.9 3.9 0.26 11.4 2.7 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EAQ84616.1 - 0.77 9.4 6.7 2.1 8.1 4.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CH PF00307.26 EAQ84617.1 - 1.2e-55 186.1 0.0 1e-14 54.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EAQ84617.1 - 5.3e-06 26.4 0.2 0.00013 21.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EAQ84617.1 - 0.0064 15.7 1.3 0.34 10.3 0.1 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EAQ84617.1 - 0.0075 16.0 0.4 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain CAMSAP_CH PF11971.3 EAQ84617.1 - 0.15 11.7 0.0 36 4.1 0.0 3.0 3 0 0 3 3 3 0 CAMSAP CH domain tRNA-synt_1b PF00579.20 EAQ84618.1 - 2.6e-57 194.1 0.0 3.3e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MBOAT PF03062.14 EAQ84619.1 - 9.7e-37 126.7 22.8 9.7e-37 126.7 15.8 2.2 3 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EAQ84619.1 - 2.8e-06 27.3 3.3 7.3e-06 25.9 2.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.17 EAQ84620.1 - 1.8e-11 43.5 0.0 2.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ84620.1 - 4.3e-08 33.0 0.0 6.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ84620.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAQ84620.1 - 0.00027 20.6 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PROL5-SMR PF15621.1 EAQ84620.1 - 1 9.8 4.2 2.1 8.8 2.9 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family MIP-T3 PF10243.4 EAQ84620.1 - 7.6 4.8 18.7 9.9 4.4 13.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 EAQ84621.1 - 2.3e-53 177.8 7.7 4.7e-25 87.1 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein OST3_OST6 PF04756.8 EAQ84622.1 - 4.3e-21 75.1 0.8 6.5e-21 74.5 0.5 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EAQ84622.1 - 0.035 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin 7TMR-DISM_7TM PF07695.6 EAQ84622.1 - 0.064 12.9 10.5 2.1 7.9 7.5 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling Abi PF02517.11 EAQ84622.1 - 1.6 8.8 5.8 4.7 7.4 4.0 2.0 1 1 0 1 1 1 0 CAAX protease self-immunity FtsJ PF01728.14 EAQ84623.1 - 7.2e-52 175.9 3.1 5.7e-51 173.0 0.0 3.1 2 2 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EAQ84623.1 - 0.017 14.8 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L18e PF00828.14 EAQ84624.1 - 6.2e-27 94.5 0.2 6.2e-27 94.5 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Glyco_hydro_6 PF01341.12 EAQ84625.1 - 1.4e-99 333.3 0.3 1.7e-99 333.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.9 EAQ84625.1 - 0.055 11.9 0.3 0.086 11.2 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Adap_comp_sub PF00928.16 EAQ84626.1 - 1.8e-60 204.2 0.0 5e-60 202.8 0.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAQ84626.1 - 4e-05 23.3 0.0 6.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hexapep PF00132.19 EAQ84627.1 - 2.1e-13 49.1 19.9 1.6e-10 39.9 1.7 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EAQ84627.1 - 8e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EAQ84627.1 - 9.3e-12 44.3 19.8 4.6e-09 35.6 0.9 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EAQ84627.1 - 1.1e-08 34.7 9.7 2.3e-08 33.7 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.1 EAQ84629.1 - 0.013 15.6 0.1 0.035 14.1 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain EMP24_GP25L PF01105.19 EAQ84630.1 - 6.7e-53 179.1 0.0 7.6e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 EAQ84630.1 - 0.056 13.9 0.0 0.084 13.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 EAQ84631.1 - 3.1e-36 124.8 0.0 4.3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84631.1 - 7.7e-14 51.3 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ84631.1 - 0.016 14.9 0.0 0.5 10.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF605 PF04652.11 EAQ84631.1 - 0.91 8.8 13.1 1.2 8.4 9.1 1.2 1 0 0 1 1 1 0 Vta1 like Nucleoporin_C PF03177.9 EAQ84632.1 - 1.9e-115 386.6 9.2 1.9e-115 386.6 6.4 1.4 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EAQ84632.1 - 7.2e-100 334.6 0.0 9.6e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like AFG1_ATPase PF03969.11 EAQ84633.1 - 3.4e-25 88.6 0.0 1.3e-18 66.9 0.0 3.1 3 0 0 3 3 3 3 AFG1-like ATPase Glyco_transf_90 PF05686.7 EAQ84634.1 - 1.7e-22 79.7 0.0 6e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Acyl_transf_1 PF00698.16 EAQ84635.1 - 5.2e-21 75.2 0.1 4.1e-14 52.6 0.0 2.2 1 1 1 2 2 2 2 Acyl transferase domain ECR1_N PF14382.1 EAQ84636.1 - 1.2e-11 43.6 0.4 3.2e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EAQ84636.1 - 0.0012 18.8 0.5 1.1 9.4 0.0 2.9 3 0 0 3 3 3 2 S1 RNA binding domain EXOSC1 PF10447.4 EAQ84636.1 - 0.0019 18.1 0.1 0.013 15.4 0.0 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Aldedh PF00171.17 EAQ84637.1 - 2.7e-70 237.0 0.0 2.2e-50 171.3 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MRP-S28 PF10213.4 EAQ84638.1 - 1.9e-47 160.4 1.2 4.7e-47 159.2 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein TerB PF05099.8 EAQ84638.1 - 0.084 12.6 1.4 0.32 10.7 0.4 2.2 1 1 0 2 2 2 0 Tellurite resistance protein TerB Glyco_tran_28_C PF04101.11 EAQ84639.1 - 4.1e-14 52.5 0.0 4.1e-14 52.5 0.0 2.5 2 1 0 2 2 1 1 Glycosyltransferase family 28 C-terminal domain AAA_23 PF13476.1 EAQ84639.1 - 0.00069 19.9 2.0 0.00085 19.7 1.4 1.2 1 0 0 1 1 1 1 AAA domain Spt20 PF12090.3 EAQ84639.1 - 0.0018 17.6 2.8 0.0033 16.7 1.9 1.5 1 0 0 1 1 1 1 Spt20 family PAT1 PF09770.4 EAQ84639.1 - 0.035 12.3 21.8 0.049 11.8 15.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 2OG-FeII_Oxy_5 PF13759.1 EAQ84639.1 - 0.05 13.8 2.8 0.15 12.3 1.9 1.7 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Suf PF05843.9 EAQ84639.1 - 0.23 11.1 12.2 0.36 10.5 8.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF912 PF06024.7 EAQ84639.1 - 0.87 9.6 4.3 1.6 8.8 3.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4557 PF15101.1 EAQ84639.1 - 0.91 9.3 18.4 1.5 8.5 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FHIPEP PF00771.15 EAQ84639.1 - 1 7.6 3.7 1.4 7.1 2.5 1.1 1 0 0 1 1 1 0 FHIPEP family Dala_Dala_lig_N PF01820.16 EAQ84639.1 - 1.2 9.4 5.2 4 7.7 3.6 1.9 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FimP PF09766.4 EAQ84639.1 - 2.1 7.3 22.0 3.8 6.4 15.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 EAQ84639.1 - 3.3 5.7 41.3 5 5.1 28.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Band_3_cyto PF07565.8 EAQ84639.1 - 7.9 5.9 9.8 12 5.2 6.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ctr PF04145.10 EAQ84639.1 - 8.3 6.4 8.1 10 6.1 4.8 1.6 2 0 0 2 2 2 0 Ctr copper transporter family WD40 PF00400.27 EAQ84640.1 - 3.1e-45 150.4 29.0 3e-08 33.2 0.3 9.9 10 0 0 10 10 10 8 WD domain, G-beta repeat Nup160 PF11715.3 EAQ84640.1 - 0.0036 15.5 0.5 0.034 12.2 0.1 2.5 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.7 EAQ84640.1 - 0.052 13.2 0.0 9.3 6.0 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lactonase PF10282.4 EAQ84640.1 - 0.057 12.4 1.3 0.08 12.0 0.1 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller RRM_6 PF14259.1 EAQ84642.1 - 1.6e-16 60.0 0.0 2.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ84642.1 - 1.9e-16 59.4 0.0 3.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ84642.1 - 9.3e-07 28.6 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.6 EAQ84642.1 - 0.013 15.9 9.7 0.032 14.7 6.7 1.7 1 0 0 1 1 1 0 Glycine rich protein family Fmp27_WPPW PF10359.4 EAQ84642.1 - 0.017 13.5 0.4 0.026 12.9 0.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 EAQ84642.1 - 0.053 11.3 0.5 0.061 11.1 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EAQ84642.1 - 0.077 11.9 0.3 0.1 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2868 PF11067.3 EAQ84642.1 - 0.15 11.1 1.2 0.18 10.9 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DivIC PF04977.10 EAQ84642.1 - 0.29 10.6 3.1 0.42 10.1 2.1 1.2 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.20 EAQ84643.1 - 3.9e-81 272.6 0.1 2.7e-69 233.7 0.0 2.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.21 EAQ84643.1 - 5.3e-33 112.5 21.6 4.5e-11 42.4 4.0 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EAQ84643.1 - 1.2e-16 60.3 0.1 3e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 C2 domain Amidohydro_3 PF07969.6 EAQ84644.1 - 4.8e-48 164.3 0.0 6e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EAQ84644.1 - 0.025 14.2 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family SPX PF03105.14 EAQ84645.1 - 5.5e-16 59.1 0.1 1.9e-15 57.4 0.1 1.9 1 1 0 1 1 1 1 SPX domain CcmD PF04995.9 EAQ84645.1 - 0.19 11.5 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Mpp10 PF04006.7 EAQ84647.1 - 2.5e-90 303.5 83.1 5e-81 272.8 24.3 2.6 1 1 1 2 2 2 2 Mpp10 protein TFIIA PF03153.8 EAQ84647.1 - 0.0077 16.1 20.4 0.0077 16.1 14.1 3.4 4 0 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit Oxidored_q6 PF01058.17 EAQ84648.1 - 5e-22 77.9 0.0 6.9e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tubulin_C PF03953.12 EAQ84649.1 - 1.6e-43 147.7 0.1 3.2e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Pox_A22 PF04848.8 EAQ84649.1 - 0.047 13.5 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 Poxvirus A22 protein PLDc PF00614.17 EAQ84650.1 - 7.3e-16 57.3 1.2 1.7e-07 30.7 0.3 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EAQ84650.1 - 3.9e-12 46.0 0.1 1.1e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EAQ84650.1 - 3.7e-07 29.9 0.1 1.1e-05 25.1 0.0 2.8 1 1 0 1 1 1 1 PX domain COQ7 PF03232.8 EAQ84651.1 - 2.8e-63 212.4 0.0 3.4e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EAQ84651.1 - 0.00062 20.1 0.0 0.00099 19.4 0.0 1.4 1 1 0 1 1 1 1 Rubrerythrin Pex14_N PF04695.8 EAQ84651.1 - 0.017 15.1 4.7 0.024 14.6 3.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 EAQ84651.1 - 0.85 8.9 8.4 1.2 8.4 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Plus-3 PF03126.13 EAQ84652.1 - 1.1e-32 112.2 0.1 2.8e-32 110.9 0.0 1.7 2 0 0 2 2 2 1 Plus-3 domain Alba PF01918.16 EAQ84654.1 - 6e-09 35.3 0.0 8.8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Alba Cut8_N PF14482.1 EAQ84654.1 - 0.58 10.1 6.7 1.7 8.7 3.1 2.9 2 1 0 2 2 2 0 Cut8 proteasome-binding domain DUF202 PF02656.10 EAQ84655.1 - 1.3e-13 50.9 4.9 2.1e-13 50.2 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2615 PF11027.3 EAQ84655.1 - 1.2 9.0 2.8 4.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) 7TMR-DISM_7TM PF07695.6 EAQ84655.1 - 2.4 7.7 9.6 8.4 6.0 6.6 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.1 EAQ84655.1 - 7.1 5.9 7.2 12 5.2 4.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.8 EAQ84656.1 - 5.5e-16 58.2 0.0 7.6e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF605 PF04652.11 EAQ84657.1 - 5.7 6.2 13.4 7.1 5.9 9.3 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EAQ84658.1 - 4.9 5.2 11.9 6.3 4.9 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2 PF00096.21 EAQ84660.1 - 2.8e-08 33.6 10.2 0.00049 20.2 1.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ84660.1 - 5.7e-07 29.4 9.7 0.0013 18.9 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ84660.1 - 3 8.2 12.2 0.068 13.4 0.9 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 EAQ84660.1 - 3.7 7.3 5.1 0.46 10.2 0.5 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FTHFS PF01268.14 EAQ84661.1 - 6.5e-256 849.6 0.1 8.6e-256 849.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EAQ84661.1 - 1.2e-68 229.2 2.8 1.3e-68 229.1 0.3 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EAQ84661.1 - 7.1e-38 129.2 0.1 1.3e-37 128.3 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IF2_N PF04760.10 EAQ84661.1 - 0.13 11.9 0.0 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region WD40 PF00400.27 EAQ84662.1 - 1.3e-33 113.6 1.2 6.8e-12 44.7 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAQ84662.1 - 3.8e-05 22.6 0.1 0.0037 16.0 0.0 2.8 1 1 2 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EAQ84662.1 - 3.8e-05 22.0 0.0 5.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EAQ84662.1 - 0.00011 21.1 0.2 0.024 13.4 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EAQ84662.1 - 0.0009 18.9 0.1 0.56 9.8 0.0 3.2 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAQ84662.1 - 0.03 12.1 0.1 0.35 8.6 0.0 1.9 1 1 1 2 2 2 0 IKI3 family Apc4_WD40 PF12894.2 EAQ84662.1 - 0.053 13.0 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.18 EAQ84663.1 - 1.9e-82 276.4 0.2 3.2e-82 275.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EAQ84663.1 - 1.5e-45 153.7 2.5 4.1e-45 152.3 1.7 1.8 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EAQ84663.1 - 7e-38 129.5 3.9 7e-38 129.5 2.7 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EAQ84663.1 - 3.1e-15 55.7 0.0 1.4e-14 53.6 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ84663.1 - 3.6e-08 33.4 0.3 2.2e-07 30.8 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAQ84663.1 - 1.4e-05 24.6 0.0 3.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EAQ84663.1 - 0.033 13.5 0.2 0.075 12.4 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EAQ84663.1 - 0.036 13.9 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF4588 PF15251.1 EAQ84664.1 - 1.6e-06 28.2 1.9 2.2e-06 27.8 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) MGC-24 PF05283.6 EAQ84665.1 - 0.034 13.9 10.9 0.039 13.7 7.6 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) CFEM PF05730.6 EAQ84665.1 - 0.076 12.8 7.2 0.14 11.9 4.9 1.7 1 1 0 1 1 1 0 CFEM domain zf-C3HC4_2 PF13923.1 EAQ84667.1 - 1.8e-08 34.2 8.2 3.1e-08 33.4 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ84667.1 - 8.1e-08 31.9 6.4 1.5e-07 31.1 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAQ84667.1 - 4.8e-07 29.3 5.8 8.4e-07 28.5 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ84667.1 - 1.3e-06 27.9 7.1 2.5e-06 27.0 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ84667.1 - 4.1e-06 26.4 5.3 7.7e-06 25.5 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EAQ84667.1 - 6.9e-06 25.8 6.1 2.9e-05 23.8 3.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAQ84667.1 - 0.00027 20.6 4.7 0.00028 20.5 2.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EAQ84667.1 - 0.046 13.5 1.3 0.1 12.4 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EAQ84667.1 - 0.052 13.0 3.9 0.096 12.2 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EAQ84667.1 - 0.15 12.1 5.1 0.42 10.7 3.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EAQ84667.1 - 0.25 10.8 8.2 1.1 8.8 5.6 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger TerY-C PF15616.1 EAQ84667.1 - 0.3 11.0 3.4 1.3 8.9 2.3 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain UBA PF00627.26 EAQ84668.1 - 0.0076 16.0 0.1 0.54 10.1 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain NAD_binding_6 PF08030.7 EAQ84669.1 - 9.9e-21 74.2 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAQ84669.1 - 5.2e-13 48.7 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EAQ84669.1 - 3.9e-11 43.1 14.6 3.9e-11 43.1 10.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EAQ84669.1 - 0.0012 19.4 0.0 0.33 11.5 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Baculo_PEP_C PF04513.7 EAQ84671.1 - 0.022 14.5 0.7 0.063 13.0 0.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-synt_B PF00430.13 EAQ84671.1 - 0.085 12.6 11.4 0.26 11.0 7.9 1.8 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1664 PF07889.7 EAQ84671.1 - 0.15 11.8 2.0 0.33 10.7 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.13 EAQ84671.1 - 0.15 11.7 1.6 0.31 10.8 1.1 1.5 1 0 0 1 1 1 0 Cobalamin adenosyltransferase WASH-7_mid PF14744.1 EAQ84671.1 - 0.2 10.4 1.2 0.31 9.8 0.9 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 TMPIT PF07851.8 EAQ84671.1 - 4.4 6.2 6.3 7.2 5.5 4.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 EAQ84671.1 - 5.5 4.7 7.6 10 3.8 5.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RTA1 PF04479.8 EAQ84672.1 - 5.8e-17 61.9 11.6 5.8e-17 61.9 8.0 2.0 1 1 1 2 2 2 1 RTA1 like protein DUF975 PF06161.6 EAQ84672.1 - 3.1 7.4 11.0 4.1 7.0 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF975) PGAP1 PF07819.8 EAQ84674.1 - 9.1e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EAQ84674.1 - 2.4e-08 34.1 0.1 3.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EAQ84674.1 - 1.4e-06 27.6 0.0 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EAQ84674.1 - 2.1e-06 27.1 0.0 3.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EAQ84674.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EAQ84674.1 - 0.0024 18.1 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EAQ84674.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EAQ84674.1 - 0.014 14.7 0.0 0.085 12.1 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 2) Ser_hydrolase PF06821.8 EAQ84674.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF915 PF06028.6 EAQ84674.1 - 0.038 13.0 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 EAQ84674.1 - 0.051 12.9 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1793 PF08760.6 EAQ84675.1 - 2.5e-63 212.9 0.1 4.3e-63 212.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Endosulfine PF04667.12 EAQ84676.1 - 1e-20 73.4 0.0 1e-20 73.4 0.0 2.1 2 1 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.8 EAQ84677.1 - 3e-127 424.4 0.0 3.5e-127 424.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.1 EAQ84678.1 - 6.8e-66 222.6 5.0 9.5e-34 117.4 0.9 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.15 EAQ84679.1 - 8e-70 235.5 0.0 9.4e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 EAQ84679.1 - 0.12 12.4 0.2 0.34 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) zf-C2H2_4 PF13894.1 EAQ84680.1 - 8 7.0 28.2 0.13 12.6 0.6 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger Not3 PF04065.10 EAQ84681.1 - 9.3e-102 339.2 21.6 1.4e-101 338.6 15.0 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EAQ84681.1 - 6.2e-36 123.2 9.7 8.3e-36 122.8 5.7 1.9 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EAQ84681.1 - 0.0014 18.0 1.4 0.0031 17.0 1.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 EAQ84681.1 - 0.0049 16.6 1.4 0.0049 16.6 0.9 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1192) Snapin_Pallidin PF14712.1 EAQ84681.1 - 0.014 15.6 9.0 0.38 11.1 0.1 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Cep57_MT_bd PF06657.8 EAQ84681.1 - 0.018 14.9 1.5 0.018 14.9 1.1 2.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Poty_PP PF08440.5 EAQ84681.1 - 0.026 13.5 2.2 0.06 12.4 1.6 1.5 1 0 0 1 1 1 0 Potyviridae polyprotein Syntaxin PF00804.20 EAQ84681.1 - 0.032 14.3 13.0 0.16 12.1 5.0 2.6 2 0 0 2 2 2 0 Syntaxin Syntaxin_2 PF14523.1 EAQ84681.1 - 0.078 13.0 8.5 0.098 12.7 4.2 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Sec5 PF15469.1 EAQ84681.1 - 0.28 10.9 10.4 0.16 11.6 2.0 2.6 3 0 0 3 3 3 0 Exocyst complex component Sec5 CENP-Q PF13094.1 EAQ84681.1 - 3.4 7.6 14.8 9.4 6.2 1.0 2.5 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 EAQ84681.1 - 3.6 7.1 17.5 0.34 10.4 2.3 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 EAQ84681.1 - 4.6 7.2 14.9 4.1 7.3 0.3 2.6 1 1 0 2 2 2 0 FlxA-like protein Tyr_Deacylase PF02580.11 EAQ84682.1 - 8.8e-32 110.0 0.0 9.5e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 EAQ84683.1 - 9e-45 152.6 0.4 1.4e-44 152.0 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EAQ84683.1 - 2.1e-10 40.1 7.7 3e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAQ84683.1 - 2.3e-08 33.3 2.3 1.9e-05 24.2 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ84683.1 - 2.6e-06 26.8 1.9 1e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ84683.1 - 0.00037 20.0 0.6 0.00094 18.8 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ84683.1 - 0.0016 18.8 2.1 0.0086 16.6 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ84683.1 - 0.0023 18.5 6.1 0.13 12.9 2.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ84683.1 - 0.0028 17.5 0.4 0.035 14.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ84683.1 - 0.0095 16.3 0.4 0.049 14.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ84683.1 - 0.014 15.2 1.2 0.037 13.8 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ84683.1 - 0.062 13.6 3.0 0.21 11.9 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.14 EAQ84684.1 - 3.4e-46 157.4 0.0 2.7e-45 154.4 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase SNF2_N PF00176.18 EAQ84686.1 - 4e-17 61.9 0.0 2.6e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_5 PF14634.1 EAQ84686.1 - 0.003 17.2 5.3 0.003 17.2 3.7 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Helicase_C_2 PF13307.1 EAQ84686.1 - 0.0052 16.7 0.3 1.2 9.0 0.3 3.0 2 1 1 3 3 3 1 Helicase C-terminal domain DNA_methylase PF00145.12 EAQ84686.1 - 0.051 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase ResIII PF04851.10 EAQ84686.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ureidogly_hydro PF04115.7 EAQ84687.1 - 9.7e-31 106.3 0.0 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase PEHE PF15275.1 EAQ84689.1 - 0.067 13.6 3.2 0.08 13.3 2.2 1.2 1 0 0 1 1 1 0 PEHE domain MFS_1 PF07690.11 EAQ84690.1 - 0.001 17.8 0.7 0.0011 17.7 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily bZIP_1 PF00170.16 EAQ84691.1 - 0.0002 21.2 15.7 0.0018 18.2 10.9 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ84691.1 - 0.0032 17.2 16.0 0.047 13.5 6.2 2.2 2 0 0 2 2 2 2 Basic region leucine zipper DUF3435 PF11917.3 EAQ84691.1 - 0.025 13.3 3.5 0.032 12.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Speriolin_N PF15058.1 EAQ84691.1 - 0.041 13.7 0.1 0.041 13.7 0.1 1.6 2 0 0 2 2 2 0 Speriolin N terminus Mnd1 PF03962.10 EAQ84691.1 - 0.047 13.3 2.7 0.061 12.9 1.9 1.1 1 0 0 1 1 1 0 Mnd1 family TSC22 PF01166.13 EAQ84691.1 - 0.95 9.4 6.9 0.18 11.7 1.1 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4570 PF15134.1 EAQ84691.1 - 5.7 6.8 11.0 8.7 6.2 7.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DUF972 PF06156.8 EAQ84691.1 - 8.3 6.8 7.3 5.7 7.3 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PseudoU_synth_2 PF00849.17 EAQ84693.1 - 1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EAQ84693.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 S4 domain Ub-Mut7C PF14451.1 EAQ84693.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin RVT_1 PF00078.22 EAQ84694.1 - 1.4e-19 70.2 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EAQ84694.1 - 0.00014 21.6 3.9 0.00028 20.6 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 EAQ84694.1 - 0.00048 20.5 0.0 0.0034 17.8 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease IncA PF04156.9 EAQ84694.1 - 0.00054 19.6 1.6 0.0021 17.7 1.1 1.9 1 0 0 1 1 1 1 IncA protein GAS PF13851.1 EAQ84694.1 - 0.0081 15.3 1.2 0.0081 15.3 0.8 2.7 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding DUF4446 PF14584.1 EAQ84694.1 - 0.2 11.4 0.9 0.66 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.6 EAQ84694.1 - 0.27 11.1 1.0 0.9 9.4 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CorA PF01544.13 EAQ84694.1 - 2.3 7.1 5.4 0.75 8.7 1.6 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 EAQ84694.1 - 4.1 5.1 3.0 2.4 5.9 0.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YCII PF03795.9 EAQ84696.1 - 0.011 15.9 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 YCII-related domain DUF724 PF05266.9 EAQ84696.1 - 0.011 15.3 1.8 0.013 15.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin PF02996.12 EAQ84696.1 - 0.029 14.0 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit HlyD PF00529.15 EAQ84696.1 - 0.12 11.6 3.3 0.14 11.4 2.3 1.2 1 0 0 1 1 1 0 HlyD family secretion protein IncA PF04156.9 EAQ84696.1 - 0.18 11.3 2.3 0.23 11.0 1.6 1.2 1 0 0 1 1 1 0 IncA protein Bombinin PF05298.6 EAQ84696.1 - 0.26 10.7 1.6 1.3 8.4 0.6 1.8 1 1 1 2 2 2 0 Bombinin DUF2852 PF11014.3 EAQ84696.1 - 0.7 9.8 4.9 1.1 9.2 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) DDE_1 PF03184.14 EAQ84697.1 - 2.8e-14 52.7 0.0 1.2e-10 40.8 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ84697.1 - 0.00066 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ84697.1 - 0.00086 18.8 0.5 0.002 17.6 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain MULE PF10551.4 EAQ84699.1 - 1.3e-13 50.8 0.0 3.3e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ84699.1 - 0.011 14.3 0.0 0.023 13.2 0.0 1.5 1 0 0 1 1 1 0 Transposase, Mutator family DDE_1 PF03184.14 EAQ84700.1 - 5.4e-50 169.5 0.0 1.3e-49 168.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ84700.1 - 6.8e-23 80.5 0.2 4.2e-22 77.9 0.1 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EAQ84700.1 - 6.8e-18 64.8 1.1 6.9e-08 32.3 0.1 3.2 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ84700.1 - 2e-09 36.8 0.1 3.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ84700.1 - 3.1e-08 33.2 0.0 1.1e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 EAQ84700.1 - 3e-05 24.7 0.1 3e-05 24.7 0.0 6.9 5 4 2 7 7 7 1 Homeodomain-like domain HTH_33 PF13592.1 EAQ84700.1 - 0.0034 16.8 0.0 0.017 14.6 0.0 2.2 1 0 0 1 1 1 1 Winged helix-turn helix DUF904 PF06005.7 EAQ84700.1 - 0.37 11.1 4.2 0.12 12.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) UvrD_C_2 PF13538.1 EAQ84701.1 - 2.7e-06 27.4 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ84701.1 - 0.00016 19.6 0.0 0.00018 19.4 0.0 1.0 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EAQ84701.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.1 EAQ84704.1 - 1.3e-31 109.7 0.8 6.8e-31 107.4 0.6 2.1 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ84704.1 - 6.4e-25 87.8 0.0 1.2e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ84704.1 - 0.0068 14.2 0.0 0.011 13.5 0.0 1.2 1 0 0 1 1 1 1 Helicase tRNA-synt_2c PF01411.14 EAQ84704.1 - 0.33 9.1 0.0 0.52 8.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (A) FAT PF02259.18 EAQ84706.1 - 1.4e-87 293.9 0.4 4.4e-87 292.3 0.3 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EAQ84706.1 - 9.1e-63 211.8 0.4 1.8e-62 210.8 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EAQ84706.1 - 1e-57 194.5 0.7 3.6e-56 189.5 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EAQ84706.1 - 9.7e-43 144.3 0.6 5.4e-42 141.9 0.0 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT PF02985.17 EAQ84706.1 - 4.9e-16 57.3 10.0 0.011 15.7 0.0 9.6 9 0 0 9 9 8 4 HEAT repeat FATC PF02260.15 EAQ84706.1 - 1.2e-15 56.6 0.1 3.9e-15 54.9 0.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EAQ84706.1 - 2.4e-14 53.3 4.8 0.00065 19.9 0.0 6.5 4 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EAQ84706.1 - 1.2e-09 38.3 9.2 0.0093 16.4 0.1 10.1 8 2 2 10 10 9 2 HEAT-like repeat Cnd1 PF12717.2 EAQ84706.1 - 4.5e-05 23.3 3.7 0.048 13.5 0.1 5.5 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EAQ84706.1 - 0.00011 20.6 5.1 0.0019 16.6 0.2 3.6 2 1 1 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 EAQ84706.1 - 0.0037 16.6 6.5 2.3 7.4 0.0 5.1 5 1 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EAQ84706.1 - 0.04 14.2 5.0 1.4e+02 2.9 0.0 6.1 5 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF615 PF04751.9 EAQ84706.1 - 0.086 12.4 5.4 17 5.0 0.7 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF615) IL7 PF01415.11 EAQ84706.1 - 0.22 11.1 0.2 0.64 9.6 0.1 1.7 1 0 0 1 1 1 0 Interleukin 7/9 family Rtf2 PF04641.7 EAQ84707.1 - 1.6e-40 138.9 2.1 4.9e-30 104.5 1.7 2.1 1 1 1 2 2 2 2 Rtf2 RING-finger zf-RING_5 PF14634.1 EAQ84707.1 - 4.9e-05 22.9 0.1 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAQ84707.1 - 0.00014 21.5 0.4 0.00032 20.3 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EAQ84707.1 - 0.0019 17.9 0.2 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAQ84707.1 - 0.011 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ84707.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 EAQ84707.1 - 0.7 9.6 4.0 14 5.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PRKCSH-like PF12999.2 EAQ84708.1 - 1e-38 132.6 8.3 1.1e-22 80.4 0.9 3.1 3 1 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EAQ84708.1 - 6.3e-24 84.2 3.3 1.2e-23 83.2 0.3 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein NuA4 PF09340.5 EAQ84708.1 - 0.0055 16.3 0.1 0.0055 16.3 0.1 3.0 4 0 0 4 4 3 1 Histone acetyltransferase subunit NuA4 NPV_P10 PF05531.7 EAQ84708.1 - 0.024 14.8 6.4 0.069 13.4 0.4 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PRKCSH PF07915.8 EAQ84708.1 - 0.042 14.6 0.1 0.11 13.3 0.1 1.8 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein PspB PF06667.7 EAQ84708.1 - 0.047 13.6 0.2 0.047 13.6 0.1 2.6 2 1 1 3 3 3 0 Phage shock protein B Prefoldin_2 PF01920.15 EAQ84708.1 - 0.13 12.0 19.1 2.3 8.0 0.1 3.9 3 1 1 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.5 EAQ84708.1 - 0.14 12.2 4.1 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MAD PF05557.8 EAQ84708.1 - 0.16 10.0 16.3 0.083 10.9 9.5 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein SPOUT_MTase PF02590.12 EAQ84708.1 - 0.16 11.6 1.0 0.29 10.8 0.7 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase DUF3837 PF12939.2 EAQ84708.1 - 0.34 10.9 0.1 0.34 10.9 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) DUF4047 PF13256.1 EAQ84708.1 - 0.64 9.9 8.6 26 4.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Laminin_II PF06009.7 EAQ84708.1 - 1.5 8.6 7.3 0.28 10.9 2.3 1.8 2 0 0 2 2 2 0 Laminin Domain II Spc24 PF08286.6 EAQ84708.1 - 1.5 8.5 11.8 1.8 8.2 1.9 3.3 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 DUF3373 PF11853.3 EAQ84708.1 - 3.1 6.2 6.7 3.9 5.8 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Filament PF00038.16 EAQ84708.1 - 3.2 7.1 22.2 1.6 8.0 0.8 2.7 2 1 1 3 3 3 0 Intermediate filament protein Syntaxin-6_N PF09177.6 EAQ84708.1 - 4.6 7.7 12.2 47 4.4 1.1 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Ldl_recept_a PF00057.13 EAQ84708.1 - 6 6.8 13.8 0.13 12.2 1.1 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A GAS PF13851.1 EAQ84708.1 - 6.6 5.8 17.6 12 5.0 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 EAQ84708.1 - 9.3 5.1 14.5 3.7 6.4 7.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GCIP PF13324.1 EAQ84709.1 - 1.9e-05 24.0 0.0 4.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF883 PF05957.8 EAQ84709.1 - 0.16 12.3 1.2 5.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.1 EAQ84709.1 - 0.75 9.4 3.1 2 8.1 2.0 1.7 2 0 0 2 2 2 0 FAM176 family DbpA PF03880.10 EAQ84711.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Methyltransf_23 PF13489.1 EAQ84712.1 - 1.5e-10 40.9 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84712.1 - 3.3e-05 24.2 0.0 0.0002 21.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84712.1 - 0.0029 18.0 0.0 0.0095 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cyto_heme_lyase PF01265.12 EAQ84713.1 - 5.6e-76 255.5 0.0 7.9e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 EAQ84714.1 - 3e-27 94.9 0.0 4.4e-24 84.7 0.0 2.4 1 1 0 1 1 1 1 ABC1 family APH PF01636.18 EAQ84714.1 - 0.0043 16.8 1.6 0.017 14.8 0.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_71 PF03659.9 EAQ84715.1 - 6.9e-38 130.1 4.3 1.1e-37 129.4 3.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 RhgB_N PF09284.5 EAQ84716.1 - 1.9e-117 390.9 5.6 3.1e-117 390.3 3.9 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EAQ84716.1 - 5.6e-55 185.5 0.0 1.8e-54 183.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EAQ84716.1 - 3.6e-16 59.0 2.3 8.8e-16 57.8 1.6 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EAQ84716.1 - 0.00016 21.6 1.9 0.00016 21.6 1.3 3.3 3 1 1 4 4 4 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 EAQ84716.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Peptidase_M28 PF04389.12 EAQ84717.1 - 2.5e-38 131.5 0.1 4.7e-38 130.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAQ84717.1 - 4e-08 32.9 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EAQ84717.1 - 0.0017 17.6 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Sugar_tr PF00083.19 EAQ84718.1 - 1.8e-44 152.0 10.6 5.9e-32 110.8 0.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84718.1 - 4.5e-14 51.9 20.5 3.9e-07 29.1 4.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EAQ84718.1 - 0.067 11.6 0.1 0.088 11.3 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier Aldo_ket_red PF00248.16 EAQ84720.1 - 5.9e-30 104.0 0.0 3.8e-14 52.1 0.0 2.6 1 1 1 2 2 2 2 Aldo/keto reductase family FYVE PF01363.16 EAQ84721.1 - 0.54 10.1 4.3 1.2 9.0 3.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger Peptidase_S49_N PF08496.5 EAQ84721.1 - 1.9 8.2 4.6 4.9 6.9 3.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3043 PF11241.3 EAQ84721.1 - 2.6 7.6 11.4 0.29 10.6 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) ABC_tran PF00005.22 EAQ84724.1 - 2.9e-18 66.4 0.0 4.5e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EAQ84724.1 - 9.8e-10 37.9 0.3 1.5e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.1 EAQ84724.1 - 7.9e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EAQ84724.1 - 2e-05 23.8 0.1 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAQ84724.1 - 5.2e-05 22.7 0.2 0.00013 21.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EAQ84724.1 - 8.3e-05 22.6 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EAQ84724.1 - 0.00069 19.1 0.1 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EAQ84724.1 - 0.0019 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAQ84724.1 - 0.0026 17.2 0.2 0.0055 16.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EAQ84724.1 - 0.0041 16.3 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EAQ84724.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAQ84724.1 - 0.022 14.9 0.1 0.06 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAQ84724.1 - 0.025 14.9 0.0 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EAQ84724.1 - 0.1 13.4 0.1 0.23 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Bac_surface_Ag PF01103.18 EAQ84725.1 - 7.3e-41 140.6 0.1 9.7e-41 140.2 0.1 1.2 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 EAQ84726.1 - 2.2e-25 88.7 0.1 3e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAQ84726.1 - 0.16 11.9 0.3 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 RWD domain Glyco_hydro_2_N PF02837.13 EAQ84727.1 - 1.2e-07 31.4 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EAQ84727.1 - 6.8e-06 26.4 0.3 7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EAQ84727.1 - 8.6e-06 24.8 0.0 1.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Aldo_ket_red PF00248.16 EAQ84728.1 - 3.9e-69 232.6 0.0 4.8e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.18 EAQ84730.1 - 2.4e-70 237.0 34.7 4.7e-44 150.8 9.5 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ84730.1 - 2.6e-29 102.2 0.0 2.6e-27 95.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EAQ84730.1 - 7.2e-07 28.6 0.0 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAQ84730.1 - 0.0001 21.7 0.0 0.0003 20.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EAQ84730.1 - 0.0013 18.7 0.0 0.8 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAQ84730.1 - 0.0023 18.0 0.1 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAQ84730.1 - 0.02 14.2 0.1 0.058 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ84730.1 - 0.022 15.5 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAQ84730.1 - 0.03 13.4 0.1 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EAQ84730.1 - 0.034 14.4 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAQ84730.1 - 0.04 13.1 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ84730.1 - 0.13 12.2 0.4 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EAQ84730.1 - 0.24 11.7 0.0 0.53 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FSH1 PF03959.8 EAQ84731.1 - 5.9e-21 74.8 0.0 1.5e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 EAQ84731.1 - 0.019 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain KR PF08659.5 EAQ84732.1 - 5.9e-61 205.2 0.5 5e-60 202.2 0.4 2.5 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EAQ84732.1 - 3.5e-59 200.7 0.0 5.2e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EAQ84732.1 - 4.8e-52 176.9 0.1 2.4e-32 112.4 0.0 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EAQ84732.1 - 7.9e-49 165.7 0.6 4e-48 163.4 0.4 2.4 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EAQ84732.1 - 4.6e-43 147.4 0.0 1e-42 146.3 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EAQ84732.1 - 7.6e-23 80.6 0.1 9.6e-21 73.8 0.0 3.1 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EAQ84732.1 - 7e-17 61.1 0.2 7.2e-16 57.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ84732.1 - 4.8e-11 43.6 0.0 2e-10 41.6 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ84732.1 - 1.2e-06 28.2 0.0 3.7e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EAQ84732.1 - 1.2e-05 25.4 0.3 9.8e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site NmrA PF05368.8 EAQ84732.1 - 0.0029 16.8 0.2 0.0029 16.8 0.2 2.2 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.15 EAQ84732.1 - 0.024 14.7 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EAQ84733.1 - 6.4e-62 209.6 14.0 4e-44 150.9 0.1 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 EAQ84733.1 - 0.79 8.0 13.0 0.016 13.6 3.5 2.0 2 1 1 3 3 3 0 MFS/sugar transport protein PAP_assoc PF03828.14 EAQ84734.1 - 2.4e-14 52.9 0.1 5.1e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EAQ84734.1 - 9.5e-06 25.8 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4384 PF14326.1 EAQ84734.1 - 0.082 12.7 0.2 0.27 11.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Actin PF00022.14 EAQ84735.1 - 2.5e-103 345.5 0.0 3.1e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Actin Ldh_2 PF02615.9 EAQ84736.1 - 1.5e-99 332.9 0.0 1.7e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.19 EAQ84737.1 - 9.5e-77 258.4 22.3 1.1e-76 258.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84737.1 - 5.1e-16 58.3 59.2 4.3e-14 51.9 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtE PF01769.11 EAQ84737.1 - 0.57 10.4 11.8 0.15 12.3 0.2 3.2 2 1 1 3 3 3 0 Divalent cation transporter Peptidase_A4 PF01828.12 EAQ84738.1 - 1.6e-42 144.9 7.3 2.2e-42 144.5 5.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family fn3 PF00041.16 EAQ84738.1 - 0.014 15.5 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Fibronectin type III domain CCT PF06203.9 EAQ84739.1 - 0.033 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 CCT motif UFD1 PF03152.9 EAQ84740.1 - 5e-24 84.3 0.0 1.8e-20 72.7 0.0 3.3 2 1 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 zf-TRAF PF02176.13 EAQ84740.1 - 0.45 10.9 15.2 3.2 8.1 0.1 3.8 2 1 1 3 3 3 0 TRAF-type zinc finger DDE_3 PF13358.1 EAQ84741.1 - 7.6e-18 64.6 0.1 1.3e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ84741.1 - 2.5e-07 30.6 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Transposase rve PF00665.21 EAQ84741.1 - 0.00059 19.9 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 EAQ84741.1 - 0.0029 17.1 0.1 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain DUF3007 PF11460.3 EAQ84741.1 - 0.026 14.6 0.3 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) HTH_38 PF13936.1 EAQ84741.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.11 EAQ84742.1 - 6.1e-51 173.1 37.1 7e-51 173.0 25.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ84742.1 - 2.4e-16 59.3 4.6 2.4e-16 59.3 3.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EAQ84742.1 - 0.00064 17.9 2.8 0.001 17.2 1.9 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Abhydrolase_6 PF12697.2 EAQ84744.1 - 2.1e-28 99.7 5.0 2.5e-28 99.5 3.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ84744.1 - 1.3e-12 47.6 0.6 1.2e-11 44.5 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ84744.1 - 1.5e-08 34.5 0.0 3.6e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAQ84744.1 - 0.00092 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 EAQ84744.1 - 0.023 14.6 0.2 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF464 PF04327.7 EAQ84748.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF464) Glyco_hydro_3 PF00933.16 EAQ84751.1 - 1.3e-84 283.7 0.0 2.4e-84 282.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ank_2 PF12796.2 EAQ84751.1 - 7.5e-73 240.9 0.2 1.7e-17 63.5 0.0 6.9 3 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84751.1 - 3.3e-62 203.3 0.9 2.9e-06 26.7 0.0 13.0 11 1 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 EAQ84751.1 - 4.8e-50 166.4 7.2 1.8e-07 31.1 0.0 9.7 5 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84751.1 - 4.3e-47 153.3 0.1 0.0012 18.8 0.0 13.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 EAQ84751.1 - 3.7e-45 151.5 4.8 1.8e-08 34.6 0.0 9.7 5 3 4 9 9 9 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EAQ84751.1 - 1.3e-14 53.7 0.3 2.2e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EAQ84751.1 - 1.5e-09 37.7 1.1 1.9e-09 37.3 0.1 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAQ84751.1 - 1.7e-07 31.4 1.0 1.6e-06 28.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Glyco_hydro_3_C PF01915.17 EAQ84751.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Viral_helicase1 PF01443.13 EAQ84751.1 - 0.079 12.4 0.0 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EAQ84751.1 - 0.083 13.0 0.0 0.26 11.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAQ84751.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PAN_4 PF14295.1 EAQ84753.1 - 0.027 14.1 0.1 0.098 12.3 0.1 1.9 1 1 0 1 1 1 0 PAN domain Dabb PF07876.7 EAQ84754.1 - 0.001 19.4 0.1 0.0032 17.8 0.0 1.8 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1183 PF06682.7 EAQ84757.1 - 0.055 13.0 6.9 0.066 12.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Pex24p PF06398.6 EAQ84758.1 - 6.1e-104 347.6 0.0 7.8e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Sporozoite_P67 PF05642.6 EAQ84758.1 - 0.79 7.5 7.5 0.051 11.4 0.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen HCV_core PF01542.13 EAQ84761.1 - 0.015 15.6 0.2 0.036 14.4 0.2 1.7 1 0 0 1 1 1 0 Hepatitis C virus core protein ADH_zinc_N PF00107.21 EAQ84762.1 - 5.7e-12 45.3 0.2 9.8e-12 44.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ84762.1 - 1.4e-08 34.5 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.22 EAQ84762.1 - 0.0033 17.8 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PXB PF12828.2 EAQ84766.1 - 4.1e-36 123.6 0.0 9.6e-36 122.4 0.0 1.6 1 0 0 1 1 1 1 PX-associated DUF3818 PF12825.2 EAQ84766.1 - 1.5e-14 53.4 0.0 3.5e-07 29.2 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) Maf1 PF09174.5 EAQ84766.1 - 0.062 13.1 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Maf1 regulator zf-C4H2 PF10146.4 EAQ84766.1 - 6.5 6.7 6.7 23 4.9 1.1 3.0 2 1 1 3 3 3 0 Zinc finger-containing protein Cu-oxidase_3 PF07732.10 EAQ84767.1 - 3.7e-29 100.8 0.0 3.3e-28 97.7 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EAQ84767.1 - 3.6e-25 88.7 0.0 7.5e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ84767.1 - 5.7e-22 77.7 4.7 5.1e-20 71.3 0.7 3.9 3 2 0 3 3 3 2 Multicopper oxidase DUF3245 PF11595.3 EAQ84768.1 - 0.025 14.8 0.6 0.025 14.8 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Thiolase_N PF00108.18 EAQ84770.1 - 2.7e-74 249.4 2.5 3.9e-74 248.9 1.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAQ84770.1 - 4.2e-41 139.2 1.7 1.1e-40 137.9 1.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain RVT_1 PF00078.22 EAQ84772.1 - 5e-41 140.4 0.0 3e-39 134.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ84772.1 - 3.9e-14 52.2 0.0 1.9e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ84772.1 - 7.1e-10 39.2 0.1 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vint PF14623.1 EAQ84773.1 - 2.8e-53 179.7 0.0 4e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EAQ84773.1 - 5.3e-31 106.5 0.0 1.1e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EAQ84773.1 - 2.4e-18 66.8 0.0 6.3e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EAQ84773.1 - 2.6e-11 43.5 0.0 9.9e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 EAQ84773.1 - 6.6e-09 35.6 0.0 4e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint_2 PF13403.1 EAQ84773.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Hint domain Ribosomal_L13e PF01294.13 EAQ84774.1 - 7.6e-63 211.2 5.4 9.8e-63 210.8 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L50 PF10501.4 EAQ84775.1 - 3e-23 81.9 0.0 6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S COX14 PF14880.1 EAQ84776.1 - 8.7e-20 70.1 0.4 8.7e-20 70.1 0.3 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Mito_fiss_reg PF05308.6 EAQ84776.1 - 0.018 14.4 2.1 0.025 13.9 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Pneumo_att_G PF05539.6 EAQ84776.1 - 0.17 11.2 4.4 0.22 10.8 3.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Lamp PF01299.12 EAQ84776.1 - 0.21 10.7 5.5 0.3 10.1 3.8 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Pex14_N PF04695.8 EAQ84776.1 - 0.24 11.4 4.0 0.13 12.3 1.5 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 EAQ84776.1 - 3.7 7.8 8.2 6.5 7.0 5.6 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) RVT_2 PF07727.9 EAQ84778.1 - 1.2e-58 197.9 0.0 2.1e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ84778.1 - 1.2e-14 54.4 0.0 3.5e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ84778.1 - 0.0017 17.9 0.0 0.0053 16.3 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain DZR PF12773.2 EAQ84778.1 - 2.8 7.8 9.4 2 8.2 3.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon ketoacyl-synt PF00109.21 EAQ84779.1 - 6.2e-75 251.9 1.1 1.2e-74 251.0 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAQ84779.1 - 6.6e-38 129.2 0.7 1.4e-37 128.1 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EAQ84779.1 - 6.8e-18 64.9 0.0 5e-17 62.1 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ84779.1 - 3.1e-15 56.1 1.4 7e-15 55.0 1.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EAQ84779.1 - 1.1e-12 47.9 0.2 9.5e-10 38.4 0.0 3.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84779.1 - 1.3e-12 48.0 0.1 3.5e-09 37.0 0.0 4.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ84779.1 - 8.8e-10 38.3 0.0 3.8e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ84779.1 - 1e-07 32.5 0.0 4.5e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EAQ84779.1 - 2.5e-06 27.2 0.0 9.1e-06 25.4 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ84779.1 - 4.8e-06 25.9 0.0 0.0028 16.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_26 PF13659.1 EAQ84779.1 - 7.3e-06 26.0 0.2 8.9e-05 22.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.18 EAQ84779.1 - 7.8e-05 21.7 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.8 EAQ84779.1 - 0.00014 21.4 0.1 0.08 12.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ubie_methyltran PF01209.13 EAQ84779.1 - 0.00027 20.1 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EAQ84779.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DLH PF01738.13 EAQ84779.1 - 0.012 14.8 0.2 0.42 9.8 0.0 3.0 4 0 0 4 4 4 0 Dienelactone hydrolase family Acyl_transf_1 PF00698.16 EAQ84779.1 - 0.016 14.5 0.2 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Acyl transferase domain Methyltransf_16 PF10294.4 EAQ84779.1 - 0.052 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EAQ84779.1 - 0.56 9.1 0.0 0.97 8.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AXE1 PF05448.7 EAQ84779.1 - 1.7 7.0 0.1 2.9 6.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) p450 PF00067.17 EAQ84780.1 - 2.3e-11 42.9 0.0 2.9e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CcmH PF03918.9 EAQ84780.1 - 0.0094 14.9 0.2 0.018 14.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome C biogenesis protein Lipase_GDSL_2 PF13472.1 EAQ84781.1 - 2.4e-10 40.8 0.5 5.5e-10 39.6 0.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ84781.1 - 5.9e-08 32.8 0.1 1.3e-07 31.7 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EAQ84781.1 - 0.034 13.8 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RVT_1 PF00078.22 EAQ84782.1 - 4.2e-09 36.0 0.0 6.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4243 PF14027.1 EAQ84783.1 - 2.9e-64 217.6 2.4 3.6e-64 217.2 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) FAD_binding_3 PF01494.14 EAQ84784.1 - 1.5e-13 50.5 0.8 0.00013 21.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EAQ84784.1 - 6.3e-10 38.4 0.9 8.3e-07 28.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EAQ84784.1 - 5.8e-07 28.5 0.8 0.00026 19.7 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EAQ84784.1 - 2.4e-06 26.6 0.5 4.2e-06 25.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ84784.1 - 4.1e-06 26.7 0.4 4.1e-06 26.7 0.3 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ84784.1 - 2.5e-05 24.2 0.1 0.00061 19.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ84784.1 - 0.00094 18.3 0.4 0.0014 17.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ84784.1 - 0.0015 17.1 0.1 0.0027 16.2 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EAQ84784.1 - 0.0051 15.7 0.5 0.012 14.5 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EAQ84784.1 - 0.012 16.0 0.5 0.07 13.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EAQ84784.1 - 0.012 14.6 1.5 0.77 8.7 0.1 2.4 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EAQ84784.1 - 0.016 14.1 0.8 2.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein RPA_interact_N PF14766.1 EAQ84784.1 - 0.095 12.1 0.6 0.18 11.2 0.4 1.4 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Zn_clus PF00172.13 EAQ84785.1 - 1.5e-05 24.7 9.6 1.5e-05 24.7 6.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 EAQ84785.1 - 0.087 10.9 0.2 0.13 10.3 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 EAQ84786.1 - 1e-09 37.6 10.5 1.4e-09 37.2 7.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4328 PF14219.1 EAQ84786.1 - 0.016 14.5 0.4 0.055 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Fungal_trans PF04082.13 EAQ84787.1 - 0.00011 21.2 0.1 0.00015 20.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAHP_synth_1 PF00793.15 EAQ84788.1 - 4.5e-102 340.3 0.1 5.5e-102 340.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.11 EAQ84790.1 - 1.2e-37 129.4 18.3 1.2e-37 129.4 12.7 3.7 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ84790.1 - 2.7e-12 46.0 9.6 2.7e-12 46.0 6.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ84790.1 - 3.4e-12 45.3 9.7 3.4e-12 45.3 6.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Podoplanin PF05808.6 EAQ84792.1 - 0.00056 19.4 1.5 0.00087 18.8 1.1 1.3 1 0 0 1 1 1 1 Podoplanin SSP160 PF06933.6 EAQ84792.1 - 0.019 12.9 10.3 0.025 12.5 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 EAQ84792.1 - 0.019 12.8 3.5 0.025 12.4 2.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4611 PF15387.1 EAQ84792.1 - 0.03 14.4 1.0 0.053 13.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 EAQ84792.1 - 0.11 12.3 0.9 0.15 11.8 0.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal UPF0370 PF13980.1 EAQ84792.1 - 0.13 12.0 1.0 0.24 11.2 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) SKG6 PF08693.5 EAQ84792.1 - 0.17 11.1 0.3 0.17 11.1 0.2 1.9 2 0 0 2 2 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 EAQ84792.1 - 0.23 11.1 3.2 0.35 10.5 2.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Menin PF05053.8 EAQ84792.1 - 0.82 7.7 10.5 3 5.8 7.3 1.7 1 1 1 2 2 2 0 Menin Pex16 PF08610.5 EAQ84792.1 - 1.3 7.9 3.3 1.8 7.4 2.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SOG2 PF10428.4 EAQ84792.1 - 8.1 4.9 13.4 9.9 4.6 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_4 PF12799.2 EAQ84793.1 - 1.3e-36 123.6 45.7 1.8e-08 33.8 2.6 10.5 7 3 5 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ84793.1 - 4e-31 106.5 42.9 1.6e-08 34.1 5.8 9.0 5 2 6 11 11 11 9 Leucine rich repeat LRR_1 PF00560.28 EAQ84793.1 - 6.3e-19 65.0 43.7 0.0097 15.8 0.5 15.1 15 1 0 15 15 15 6 Leucine Rich Repeat LRR_6 PF13516.1 EAQ84793.1 - 2.3e-13 48.6 30.5 0.59 10.3 0.1 12.9 13 0 0 13 13 13 4 Leucine Rich repeat LRR_7 PF13504.1 EAQ84793.1 - 2.5e-12 44.8 45.9 0.41 11.0 0.0 13.6 13 0 0 13 13 13 5 Leucine rich repeat LRR_9 PF14580.1 EAQ84793.1 - 0.052 13.1 5.1 8.9 5.8 0.0 4.3 2 2 2 4 4 4 0 Leucine-rich repeat DPM3 PF08285.6 EAQ84794.1 - 1e-33 115.0 0.1 1.1e-33 114.8 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Vmethyltransf_C PF08456.5 EAQ84794.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Oxidored-like PF09791.4 EAQ84796.1 - 3.7e-26 90.2 5.3 1.2e-25 88.6 3.7 2.0 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ELL PF10390.4 EAQ84796.1 - 0.76 8.9 6.6 1.2 8.2 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Mitofilin PF09731.4 EAQ84796.1 - 8.7 4.8 9.7 11 4.5 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pribosyltran PF00156.22 EAQ84797.1 - 4.4e-10 39.3 0.2 1.5e-09 37.6 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain dCMP_cyt_deam_1 PF00383.17 EAQ84799.1 - 3e-14 52.4 0.0 3.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EAQ84799.1 - 0.00044 19.9 0.0 0.0021 17.7 0.0 1.8 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SRP-alpha_N PF04086.8 EAQ84801.1 - 0.0019 17.6 4.2 0.0019 17.6 2.9 1.5 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 EAQ84802.1 - 1.2e-39 136.0 0.0 1.6e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84802.1 - 5.8e-22 77.9 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ84802.1 - 1.1e-05 24.6 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EAQ84802.1 - 0.067 12.5 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EAQ84802.1 - 0.24 10.4 0.1 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLAC8 PF04749.12 EAQ84805.1 - 8.7e-24 84.1 18.7 1.1e-23 83.7 12.9 1.1 1 0 0 1 1 1 1 PLAC8 family DUF3287 PF11690.3 EAQ84805.1 - 0.11 12.5 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Spt4 PF06093.8 EAQ84807.1 - 8.1 6.3 7.5 4.1 7.3 0.1 2.9 2 1 1 3 3 3 0 Spt4/RpoE2 zinc finger Fungal_trans PF04082.13 EAQ84808.1 - 3.4e-14 52.3 0.1 6.2e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPR1 PF15356.1 EAQ84808.1 - 0.65 10.3 10.1 3.8 7.8 1.6 2.8 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Bac_chlorC PF02043.12 EAQ84808.1 - 6.5 6.6 5.6 6.1 6.7 1.0 2.4 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein PIF1 PF05970.9 EAQ84809.1 - 4.5e-20 71.9 0.0 6.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ84809.1 - 7.3e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ84809.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ank_2 PF12796.2 EAQ84810.1 - 7e-109 356.4 15.5 1.7e-22 79.5 0.1 6.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84810.1 - 1.5e-101 327.4 25.5 5e-07 29.2 0.0 14.6 14 0 0 14 14 14 14 Ankyrin repeat Ank_5 PF13857.1 EAQ84810.1 - 3.6e-64 211.3 16.9 1.4e-05 25.1 0.1 12.4 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ84810.1 - 4.1e-63 208.7 14.3 4e-06 27.1 0.1 13.6 1 1 12 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84810.1 - 4.1e-51 165.8 7.7 0.0074 16.4 0.0 14.6 14 0 0 14 14 14 12 Ankyrin repeat PNP_UDP_1 PF01048.15 EAQ84810.1 - 3.7e-09 35.8 0.4 1.6e-08 33.7 0.3 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EAQ84810.1 - 1.9e-08 34.1 0.2 3.8e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ84810.1 - 3.8e-07 30.2 1.7 3.8e-06 27.0 0.4 2.7 2 0 0 2 2 2 1 AAA ATPase domain UBA PF00627.26 EAQ84810.1 - 3.6e-06 26.6 0.0 54 3.8 0.0 9.1 10 0 0 10 10 10 0 UBA/TS-N domain Fe-S_assembly PF04384.8 EAQ84810.1 - 8.7e-06 26.0 1.2 1.7e+02 2.6 0.0 8.3 9 0 0 9 9 9 0 Iron-sulphur cluster assembly DUF1843 PF08898.5 EAQ84810.1 - 0.00014 21.7 26.3 1.5 8.9 0.1 8.2 6 3 2 8 8 8 4 Domain of unknown function (DUF1843) NB-ARC PF00931.17 EAQ84810.1 - 0.00087 18.2 0.1 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EAQ84810.1 - 0.015 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAQ84810.1 - 0.022 14.6 0.1 0.45 10.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain UPF0184 PF03670.8 EAQ84810.1 - 0.046 13.8 0.1 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Arch_ATPase PF01637.13 EAQ84810.1 - 0.052 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase PIF1 PF05970.9 EAQ84811.1 - 3.3e-14 52.6 0.0 6.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase PNP_UDP_1 PF01048.15 EAQ84811.1 - 1.1e-09 37.6 0.2 8.3e-09 34.7 0.1 2.6 2 1 0 2 2 2 1 Phosphorylase superfamily UvrD_C_2 PF13538.1 EAQ84811.1 - 0.00064 19.8 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain NACHT PF05729.7 EAQ84811.1 - 0.017 14.7 0.1 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RVT_1 PF00078.22 EAQ84812.1 - 1e-21 77.3 0.0 1.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EAQ84813.1 - 1e-16 60.9 0.0 1.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NACHT PF05729.7 EAQ84814.1 - 3.8e-08 33.1 1.5 0.0005 19.7 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EAQ84814.1 - 7e-06 26.2 0.3 0.00067 19.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ84814.1 - 5.7e-05 23.1 6.4 0.0052 16.7 4.5 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EAQ84814.1 - 0.00082 19.7 8.4 0.71 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ84814.1 - 0.0016 18.2 0.0 0.0077 15.9 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EAQ84814.1 - 0.0025 17.9 0.1 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 EAQ84814.1 - 0.0052 15.6 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EAQ84814.1 - 0.0054 16.2 0.5 0.033 13.6 0.0 2.4 2 1 1 3 3 3 1 AAA-like domain ABC_tran PF00005.22 EAQ84814.1 - 0.022 15.0 0.1 0.064 13.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter DUF676 PF05057.9 EAQ84814.1 - 0.026 13.8 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Myosin_tail_1 PF01576.14 EAQ84814.1 - 0.029 12.0 3.7 0.043 11.5 2.5 1.1 1 0 0 1 1 1 0 Myosin tail AAA_33 PF13671.1 EAQ84814.1 - 0.039 13.8 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EAQ84814.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Abhydrolase_6 PF12697.2 EAQ84814.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_17 PF13207.1 EAQ84814.1 - 0.047 14.5 0.0 0.22 12.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain Ank_2 PF12796.2 EAQ84814.1 - 0.066 13.5 0.0 0.58 10.5 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Nsp1_C PF05064.8 EAQ84814.1 - 0.085 12.4 4.1 0.21 11.2 2.8 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region FBP PF07299.6 EAQ84814.1 - 0.13 11.5 0.8 0.25 10.6 0.6 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) AAA PF00004.24 EAQ84814.1 - 0.14 12.3 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Jnk-SapK_ap_N PF09744.4 EAQ84814.1 - 0.14 12.0 4.5 0.28 11.1 3.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_25 PF13481.1 EAQ84814.1 - 0.18 11.2 0.0 0.64 9.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EAQ84814.1 - 0.23 10.9 1.8 0.78 9.2 1.2 1.7 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EAQ84814.1 - 0.38 8.5 2.7 0.56 7.9 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EAQ84814.1 - 0.55 9.9 2.1 1.1 8.9 1.4 1.4 1 0 0 1 1 1 0 Laminin Domain II AAA_13 PF13166.1 EAQ84814.1 - 5.2 5.4 7.7 27 3.0 5.3 1.9 1 1 0 1 1 1 0 AAA domain DUF342 PF03961.8 EAQ84814.1 - 5.9 5.1 4.1 9.7 4.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MFS_1 PF07690.11 EAQ84815.1 - 5e-10 38.6 50.1 8.7e-06 24.6 10.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAQ84815.1 - 0.0052 15.0 19.0 0.004 15.4 11.4 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1843 PF08898.5 EAQ84817.1 - 0.12 12.4 0.8 0.26 11.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) HMGL-like PF00682.14 EAQ84818.1 - 4.5e-29 101.7 0.8 9.3e-22 77.8 0.0 2.7 2 1 1 3 3 3 2 HMGL-like NRDE PF05742.7 EAQ84821.1 - 9.5e-36 123.5 0.0 9.5e-25 87.4 0.0 3.0 1 1 1 2 2 2 2 NRDE protein Tfb2 PF03849.9 EAQ84823.1 - 3.9e-141 469.9 0.0 6.5e-141 469.2 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EAQ84823.1 - 2.1e-05 24.2 0.0 5.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EAQ84823.1 - 0.079 12.4 0.2 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Anti-repressor SinI 4HBT PF03061.17 EAQ84824.1 - 1.7e-13 50.4 0.1 2.6e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EAQ84824.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EAQ84824.1 - 0.076 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Peptidase_A4 PF01828.12 EAQ84825.1 - 3.9e-70 235.1 0.4 4.6e-70 234.9 0.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family DUF3938 PF13074.1 EAQ84827.1 - 0.079 12.8 0.6 6.1 6.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) MFS_1 PF07690.11 EAQ84828.1 - 3.5e-21 75.3 24.2 9.9e-21 73.8 16.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.11 EAQ84830.1 - 2.9e-13 49.4 0.0 4.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ84830.1 - 5.5e-10 38.6 0.0 8.8e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EAQ84830.1 - 0.00042 20.2 0.1 0.014 15.4 0.0 3.1 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EAQ84830.1 - 0.00068 19.2 0.2 0.038 13.6 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain Phage_CP76 PF06892.6 EAQ84830.1 - 0.0054 16.0 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Phage regulatory protein CII (CP76) CENP-B_N PF04218.8 EAQ84830.1 - 0.11 11.9 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain EFG_II PF14492.1 EAQ84830.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II TB2_DP1_HVA22 PF03134.14 EAQ84831.1 - 6.2e-31 105.9 7.4 9.4e-31 105.4 5.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.7 EAQ84832.1 - 1.8e-90 300.7 0.0 2.3e-90 300.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 SARG PF15385.1 EAQ84832.1 - 0.017 14.5 3.2 0.021 14.1 2.2 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein CHCH PF06747.8 EAQ84833.1 - 7.9e-06 25.6 3.5 9.7e-06 25.3 2.5 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 EAQ84833.1 - 0.092 12.7 0.4 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Toxin_25 PF08095.6 EAQ84833.1 - 9.1 6.1 9.4 1.7e+02 2.0 6.5 2.3 1 1 0 1 1 1 0 Hefutoxin family BPL_N PF09825.4 EAQ84834.1 - 3.9e-149 496.4 0.0 4.9e-149 496.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EAQ84834.1 - 4.5e-21 75.1 0.0 9.3e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HeLo PF14479.1 EAQ84837.1 - 3.2e-38 131.6 0.1 4.5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Dfp1_Him1_M PF08630.5 EAQ84837.1 - 0.074 12.8 0.4 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 Dfp1/Him1, central region WD40 PF00400.27 EAQ84838.1 - 1.7e-90 293.9 22.5 1.3e-13 50.2 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat NACHT PF05729.7 EAQ84838.1 - 5.6e-20 71.6 0.1 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EAQ84838.1 - 4.7e-09 35.7 1.3 22 4.8 0.0 6.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EAQ84838.1 - 3.3e-07 29.4 1.0 40 3.6 0.0 6.3 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF1652 PF07865.6 EAQ84838.1 - 1.7e-06 27.4 0.0 23 4.6 0.0 6.3 3 2 3 6 6 6 0 Protein of unknown function (DUF1652) DUF642 PF04862.7 EAQ84838.1 - 1.9e-05 24.3 0.8 1 8.9 0.0 4.5 1 1 2 4 4 4 2 Protein of unknown function (DUF642) PQQ_2 PF13360.1 EAQ84838.1 - 2.3e-05 23.9 14.4 0.0018 17.8 8.8 3.6 1 1 1 2 2 2 2 PQQ-like domain Cytochrom_D1 PF02239.11 EAQ84838.1 - 0.0004 18.7 1.7 0.24 9.6 0.1 2.6 1 1 2 3 3 3 3 Cytochrome D1 heme domain Robl_LC7 PF03259.12 EAQ84838.1 - 0.00085 18.8 0.7 9 5.9 0.0 4.5 3 2 2 5 5 4 1 Roadblock/LC7 domain AAA_16 PF13191.1 EAQ84838.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TruB_C PF09142.6 EAQ84838.1 - 0.0038 16.8 8.1 80 2.9 0.0 6.1 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal DUF1258 PF06869.7 EAQ84838.1 - 0.0043 16.1 0.1 23 3.9 0.0 4.5 1 1 5 6 6 6 0 Protein of unknown function (DUF1258) AAA_22 PF13401.1 EAQ84838.1 - 0.009 16.1 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain PQQ_3 PF13570.1 EAQ84838.1 - 0.23 11.7 17.5 34 4.8 0.1 6.2 5 1 1 6 6 6 0 PQQ-like domain Pam16 PF03656.8 EAQ84839.1 - 5.2e-34 116.7 0.8 6.3e-34 116.5 0.5 1.0 1 0 0 1 1 1 1 Pam16 Yip1 PF04893.12 EAQ84840.1 - 2.3e-06 27.2 18.0 0.0038 16.7 6.7 2.8 2 1 1 3 3 3 2 Yip1 domain RCC1 PF00415.13 EAQ84841.1 - 4.9e-58 193.1 4.1 6e-08 32.7 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAQ84841.1 - 9.8e-38 126.9 22.0 6e-07 28.9 0.3 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EAQ84841.1 - 0.0021 17.5 0.4 0.92 9.0 0.0 2.6 2 0 0 2 2 2 2 Putative carbohydrate binding domain Methyltransf_16 PF10294.4 EAQ84843.1 - 3.2e-16 59.2 0.0 4.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAQ84843.1 - 0.0027 18.2 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ84843.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EAQ84843.1 - 0.044 13.3 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ84843.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84843.1 - 0.12 12.9 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TraH_2 PF06871.6 EAQ84845.1 - 2.2 7.6 4.3 4 6.8 0.1 2.3 2 0 0 2 2 2 0 TraH_2 DAO PF01266.19 EAQ84852.1 - 1.1e-33 116.6 4.0 4e-28 98.3 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Bunya_NS-S PF01104.12 EAQ84852.1 - 0.15 11.5 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s Methyltransf_23 PF13489.1 EAQ84853.1 - 1.8e-19 70.0 0.1 3.7e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84853.1 - 5.3e-11 42.8 0.1 3.8e-10 40.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84853.1 - 6.2e-11 42.6 0.0 2.1e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ84853.1 - 3.8e-08 33.0 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ84853.1 - 1.3e-07 32.2 0.1 1.3e-06 28.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ84853.1 - 2.1e-05 24.7 0.0 5.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EAQ84853.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.13 EAQ84853.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HgmA PF04209.8 EAQ84854.1 - 4.5e-114 381.1 0.0 2.6e-85 286.3 0.1 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Helitron_like_N PF14214.1 EAQ84856.1 - 5.2e-48 163.2 4.2 8.8e-48 162.4 2.9 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ84856.1 - 2.5e-25 89.1 0.0 1.7e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ84856.1 - 1.6e-07 31.1 0.0 4.8e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ84856.1 - 0.00011 21.8 0.1 0.00033 20.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EAQ84856.1 - 0.0026 17.8 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ84856.1 - 0.0036 15.1 0.0 0.009 13.8 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.1 EAQ84856.1 - 0.008 15.7 0.3 4 6.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain Nif11 PF07862.6 EAQ84856.1 - 0.12 12.2 0.0 0.53 10.2 0.0 2.1 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function Acyl-CoA_dh_2 PF08028.6 EAQ84859.1 - 0.0011 19.1 4.5 0.088 13.0 0.9 2.3 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain FUSC PF04632.7 EAQ84859.1 - 0.065 11.6 6.6 0.083 11.3 4.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nop14 PF04147.7 EAQ84861.1 - 0.027 12.4 2.2 0.033 12.1 1.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAQ84861.1 - 0.043 11.8 0.4 0.067 11.2 0.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EAQ84861.1 - 4.7 7.2 11.4 6.2 6.8 3.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) WD40 PF00400.27 EAQ84862.1 - 2.3e-73 239.6 17.4 8.4e-11 41.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAQ84862.1 - 2.6e-05 22.5 4.9 0.017 13.2 0.1 4.5 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ84862.1 - 0.0022 16.7 0.1 0.066 11.9 0.0 2.8 2 1 0 2 2 2 1 Nup133 N terminal like Leu_zip PF15294.1 EAQ84863.1 - 0.0045 16.1 1.1 0.0067 15.5 0.8 1.2 1 0 0 1 1 1 1 Leucine zipper Striatin PF08232.7 EAQ84863.1 - 0.55 10.5 7.8 1.7 8.9 2.9 2.3 2 0 0 2 2 2 0 Striatin family RRM_1 PF00076.17 EAQ84865.1 - 2.6e-12 46.1 0.1 5.1e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ84865.1 - 5.5e-09 35.8 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ84865.1 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAQ84865.1 - 0.0083 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EAQ84865.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-FPG_IleRS PF06827.9 EAQ84866.1 - 0.012 15.1 1.0 0.025 14.2 0.7 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Ank_2 PF12796.2 EAQ84868.1 - 2.4e-98 322.6 14.7 5.6e-20 71.4 0.1 6.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ84868.1 - 3.1e-75 244.4 1.0 8.5e-09 34.7 0.0 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 EAQ84868.1 - 2.2e-54 175.9 0.3 2e-05 24.3 0.0 10.0 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EAQ84868.1 - 5.9e-54 179.5 5.9 3.3e-09 37.0 0.0 8.3 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ84868.1 - 1.2e-46 155.6 15.9 2.9e-09 36.8 0.2 9.2 3 2 7 10 10 10 9 Ankyrin repeats (many copies) UBA PF00627.26 EAQ84868.1 - 0.02 14.7 0.7 48 3.9 0.0 4.8 5 0 0 5 5 5 0 UBA/TS-N domain AAA PF00004.24 EAQ84869.1 - 2.1e-16 60.3 0.0 3.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ84869.1 - 0.00081 19.5 0.1 0.0027 17.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ84869.1 - 0.0018 18.0 0.0 0.005 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ84869.1 - 0.0076 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAQ84869.1 - 0.014 16.1 0.0 0.053 14.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ84869.1 - 0.074 12.8 0.5 0.22 11.3 0.3 1.8 1 0 0 1 1 1 0 Part of AAA domain AF-4 PF05110.8 EAQ84870.1 - 0.047 11.5 2.8 0.068 11.0 2.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ABC2_membrane PF01061.19 EAQ84871.1 - 1.2e-41 142.1 20.6 1.2e-41 142.1 14.3 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EAQ84871.1 - 2.7e-18 66.5 0.0 4.4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAQ84871.1 - 2.3e-06 27.8 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAQ84871.1 - 0.00023 20.6 0.1 0.0008 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAQ84871.1 - 0.0004 20.2 0.4 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ84871.1 - 0.00057 19.0 0.0 0.00095 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EAQ84871.1 - 0.00069 19.0 0.1 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAQ84871.1 - 0.0015 18.5 0.1 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 EAQ84871.1 - 0.002 17.6 0.2 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EAQ84871.1 - 0.0043 16.3 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EAQ84871.1 - 0.006 17.3 0.0 0.02 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAQ84871.1 - 0.0063 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ84871.1 - 0.016 15.3 0.0 0.056 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EAQ84871.1 - 0.056 12.4 0.0 0.57 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EAQ84871.1 - 0.079 13.2 1.2 0.11 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EAQ84871.1 - 0.22 11.8 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC2_membrane_3 PF12698.2 EAQ84871.1 - 0.32 9.9 21.8 0.36 9.8 14.2 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein CK_II_beta PF01214.13 EAQ84872.1 - 4e-77 257.9 0.0 6.9e-77 257.1 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EAQ84872.1 - 0.028 15.0 5.9 0.028 15.0 4.1 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.6 EAQ84872.1 - 0.13 10.1 0.1 0.18 9.6 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 EAQ84872.1 - 0.47 8.5 1.3 0.67 7.9 0.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.1 EAQ84872.1 - 4.1 7.7 11.3 12 6.2 3.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cupin_8 PF13621.1 EAQ84873.1 - 4.5e-22 78.7 0.0 6.5e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EAQ84873.1 - 0.00081 18.8 0.0 0.0028 17.1 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.7 EAQ84873.1 - 0.027 13.7 0.0 0.069 12.3 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein DUF1295 PF06966.7 EAQ84874.1 - 2.2e-14 53.3 3.7 5.8e-14 51.9 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EAQ84874.1 - 0.0031 17.6 0.3 0.0076 16.3 0.2 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EAQ84874.1 - 0.0064 16.2 0.3 0.014 15.1 0.2 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEPCK_ATP PF01293.15 EAQ84875.1 - 1.6e-152 508.3 0.0 6.7e-139 463.4 0.0 2.1 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EAQ84875.1 - 0.016 15.5 0.1 7.2 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ84875.1 - 0.073 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAQ84875.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ84875.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain p450 PF00067.17 EAQ84876.1 - 9.4e-14 50.7 0.0 5.8e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 EF-hand_6 PF13405.1 EAQ84878.1 - 1.9e-17 61.5 4.3 1.3e-07 30.9 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EAQ84878.1 - 4.7e-17 59.9 4.5 1.1e-07 30.5 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EAQ84878.1 - 2e-16 59.8 0.3 2.3e-08 34.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAQ84878.1 - 1.5e-14 53.2 3.2 7.8e-05 22.2 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EAQ84878.1 - 6.5e-11 41.0 6.6 2e-05 23.7 0.4 3.0 3 0 0 3 3 3 2 EF hand Caleosin PF05042.8 EAQ84878.1 - 0.00091 18.8 0.0 0.062 12.8 0.0 2.0 2 0 0 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.1 EAQ84878.1 - 0.012 15.5 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EFhand_Ca_insen PF08726.5 EAQ84878.1 - 0.026 14.4 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF3322 PF11795.3 EAQ84878.1 - 0.041 13.5 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) EF-hand_4 PF12763.2 EAQ84878.1 - 0.042 13.5 0.1 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand BUD22 PF09073.5 EAQ84879.1 - 3.2e-46 158.2 43.4 2.6e-38 132.2 26.5 2.6 2 1 0 2 2 2 2 BUD22 TMF_DNA_bd PF12329.3 EAQ84880.1 - 0.07 12.9 2.6 0.12 12.1 1.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 EAQ84880.1 - 0.29 10.0 3.5 0.42 9.5 2.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EAQ84880.1 - 0.35 9.8 2.7 0.5 9.3 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EAQ84880.1 - 0.51 9.8 2.7 1 8.8 0.7 2.0 1 1 1 2 2 2 0 Septum formation initiator TSC22 PF01166.13 EAQ84880.1 - 0.55 10.2 6.1 0.9 9.5 0.7 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family ATG13 PF10033.4 EAQ84881.1 - 4.6e-72 242.2 0.2 1.4e-71 240.6 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 BAF1_ABF1 PF04684.8 EAQ84881.1 - 3 6.6 7.6 5.1 5.8 5.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RCC1 PF00415.13 EAQ84883.1 - 2.2e-20 72.5 0.1 2e-07 31.1 0.0 4.3 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EAQ84883.1 - 1.8e-12 47.2 0.0 1.7e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EAQ84883.1 - 4.2e-10 39.8 0.1 9.9e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ84883.1 - 7.4e-08 31.9 0.3 0.02 15.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.1 EAQ84883.1 - 3.2e-06 26.5 9.7 3.8e-06 26.3 0.5 3.5 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EAQ84883.1 - 3.9e-05 23.9 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ84883.1 - 0.0039 17.3 0.2 0.32 11.3 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EAQ84883.1 - 0.0045 16.7 0.2 0.039 13.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Mito_carr PF00153.22 EAQ84884.1 - 4.8e-57 189.6 1.4 3.2e-20 71.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 EAQ84884.1 - 0.07 13.0 0.2 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Uperin family VHS PF00790.14 EAQ84885.1 - 4.2e-35 120.4 0.1 8.2e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EAQ84885.1 - 1.1e-16 60.1 0.2 2.2e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ84885.1 - 1.3e-16 59.6 0.1 2.9e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ84885.1 - 1.6e-13 49.9 0.0 2.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EAQ84885.1 - 0.008 15.6 3.4 0.022 14.3 2.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif HEAT_2 PF13646.1 EAQ84885.1 - 0.16 12.2 1.1 0.34 11.2 0.2 2.0 2 0 0 2 2 2 0 HEAT repeats Fungal_trans PF04082.13 EAQ84886.1 - 1.9e-05 23.6 4.6 0.00066 18.6 0.0 2.8 3 0 0 3 3 3 2 Fungal specific transcription factor domain Gly_kinase PF02595.10 EAQ84886.1 - 0.026 13.2 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family Dynactin_p62 PF05502.8 EAQ84886.1 - 0.037 12.8 0.5 0.06 12.0 0.3 1.2 1 0 0 1 1 1 0 Dynactin p62 family zf-H2C2_2 PF13465.1 EAQ84886.1 - 0.86 10.0 3.7 0.85 10.0 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Suf PF05843.9 EAQ84886.1 - 8.6 5.9 7.4 15 5.2 5.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EAQ84886.1 - 9.2 4.3 22.3 15 3.6 15.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pectate_lyase_3 PF12708.2 EAQ84888.1 - 7e-83 278.1 19.8 3.2e-67 226.9 4.8 3.2 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EAQ84888.1 - 1.3e-05 24.5 2.3 0.015 14.7 0.1 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Prothymosin PF03247.9 EAQ84889.1 - 0.27 11.3 15.4 0.45 10.6 10.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.7 EAQ84889.1 - 1.3 8.1 9.3 1.6 7.9 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EAQ84889.1 - 5.2 4.8 12.5 5.4 4.8 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EAQ84889.1 - 7.8 5.5 12.0 14 4.7 8.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EAQ84889.1 - 9.1 4.1 8.7 9.9 4.0 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2461 PF09365.5 EAQ84890.1 - 2.4e-10 40.1 0.0 2.9e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) HNH_2 PF13391.1 EAQ84892.1 - 4e-11 42.5 0.2 9.6e-11 41.3 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease ApbA PF02558.11 EAQ84894.1 - 7.3e-33 113.1 0.0 1.2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EAQ84894.1 - 5.3e-27 94.2 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 EAQ84894.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 EAQ84896.1 - 1.8e-10 40.5 13.0 2.7e-10 39.9 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ84896.1 - 5.3e-07 28.7 0.3 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lys-AminoMut_A PF09043.6 EAQ84896.1 - 0.089 10.9 0.3 0.15 10.1 0.2 1.3 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit V_ATPase_I PF01496.14 EAQ84896.1 - 9 4.0 5.3 21 2.8 3.7 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EAQ84897.1 - 0.0022 17.7 3.4 0.0022 17.7 2.4 15.2 6 5 8 16 16 16 8 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EAQ84897.1 - 1.3 8.4 142.7 1.1 8.6 1.4 6.5 1 1 3 5 5 5 0 Intermediate filament protein Peptidase_S8 PF00082.17 EAQ84898.1 - 0.013 14.6 0.0 0.045 12.9 0.0 1.6 1 1 0 1 1 1 0 Subtilase family DUF1640 PF07798.6 EAQ84898.1 - 2.1 8.3 8.2 20 5.1 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF21 PF01595.15 EAQ84899.1 - 1.1e-30 106.3 0.0 1.7e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 T4_Gp59_C PF08994.5 EAQ84899.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Glyoxalase PF00903.20 EAQ84900.1 - 7e-41 139.2 0.1 5.2e-20 71.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EAQ84900.1 - 6.2e-32 110.4 0.1 4e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EAQ84900.1 - 2.3e-18 66.1 0.0 2e-08 34.1 0.0 3.6 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EAQ84900.1 - 4.8e-06 26.6 0.0 0.21 11.4 0.0 3.3 1 1 2 3 3 3 3 Glyoxalase-like domain CppA_N PF14506.1 EAQ84900.1 - 0.035 13.7 0.1 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal 2-Hacid_dh_C PF02826.14 EAQ84901.1 - 5.4e-53 178.7 0.0 8.5e-53 178.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ84901.1 - 1.6e-33 115.0 0.1 2.5e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 EAQ84901.1 - 0.0063 15.9 0.0 0.0063 15.9 0.0 2.5 3 0 0 3 3 3 1 ACT domain XdhC_C PF13478.1 EAQ84901.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EAQ84901.1 - 0.22 11.0 2.9 0.19 11.2 0.9 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EAQ84902.1 - 0.00014 21.1 0.0 0.00069 18.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Robl_LC7 PF03259.12 EAQ84902.1 - 0.0073 15.8 0.1 0.021 14.3 0.1 1.7 1 0 0 1 1 1 1 Roadblock/LC7 domain F-box PF00646.28 EAQ84903.1 - 0.077 12.6 0.1 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box domain Zip PF02535.17 EAQ84904.1 - 1.9e-45 155.2 0.0 2.6e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter COX15-CtaA PF02628.10 EAQ84905.1 - 1.6e-97 326.0 9.8 1.9e-97 325.8 6.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3285 PF11688.3 EAQ84905.1 - 0.49 10.0 2.9 1.8 8.2 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3285) CcoS PF03597.10 EAQ84905.1 - 1 8.8 3.7 20 4.7 0.4 3.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type BHD_3 PF10405.4 EAQ84906.1 - 1.3e-25 88.8 0.0 2.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Adenosine_kin PF04008.9 EAQ84906.1 - 0.15 11.5 0.1 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine specific kinase PTPA PF03095.10 EAQ84907.1 - 1.2e-62 211.7 0.0 1.9e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_hydro_92 PF07971.7 EAQ84908.1 - 3e-107 359.3 0.5 1.6e-74 251.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Zn_clus PF00172.13 EAQ84909.1 - 1.5e-08 34.4 6.2 3.2e-08 33.3 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ84909.1 - 0.00027 19.6 0.0 0.00036 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EAQ84910.1 - 2.2e-23 82.9 0.9 1.6e-22 80.0 0.6 2.2 1 1 0 1 1 1 1 RTA1 like protein DUF3493 PF11998.3 EAQ84910.1 - 0.92 9.4 4.0 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF2244 PF10003.4 EAQ84910.1 - 2.3 7.5 11.5 0.31 10.3 2.3 2.6 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) HECT PF00632.20 EAQ84911.1 - 2.9e-86 289.5 0.0 4e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EAQ84911.1 - 0.002 17.6 2.7 0.0063 16.0 1.8 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif UBA_2 PF08587.6 EAQ84911.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) RRM_1 PF00076.17 EAQ84912.1 - 2.9e-83 273.5 4.5 6.1e-22 77.0 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ84912.1 - 5.1e-54 180.1 0.9 2.9e-14 52.7 0.0 5.6 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ84912.1 - 7.7e-41 137.7 0.1 3.6e-10 39.5 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EAQ84912.1 - 6.4e-30 102.6 1.9 2.1e-29 101.0 1.3 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EAQ84912.1 - 0.00085 19.0 0.4 13 5.6 0.0 4.1 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EAQ84912.1 - 0.0014 18.7 0.1 17 5.7 0.0 3.9 3 1 0 3 3 3 0 Cobalamin biosynthesis central region YflT PF11181.3 EAQ84912.1 - 0.0021 18.1 5.4 0.15 12.2 0.2 3.4 3 0 0 3 3 3 1 Heat induced stress protein YflT DUF939_C PF11728.3 EAQ84912.1 - 0.021 14.6 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 DUF939 C-terminal domain Limkain-b1 PF11608.3 EAQ84912.1 - 0.028 14.1 3.7 24 4.7 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.6 EAQ84912.1 - 0.03 13.8 1.2 6.7 6.3 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Usp PF00582.21 EAQ84914.1 - 1.3e-21 77.2 4.1 9.5e-14 51.7 0.1 3.0 3 0 0 3 3 3 2 Universal stress protein family Ribosomal_S7 PF00177.16 EAQ84915.1 - 1.6e-25 89.4 0.0 2.4e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NMO PF03060.10 EAQ84916.1 - 2.3e-60 204.5 0.0 4e-60 203.6 0.0 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAQ84916.1 - 4e-06 25.9 0.0 0.00098 18.1 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAQ84916.1 - 0.0027 16.6 0.1 0.0047 15.8 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.9 EAQ84916.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PEX11 PF05648.9 EAQ84917.1 - 2.2e-75 252.7 0.7 2.5e-75 252.5 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Chal_sti_synt_N PF00195.14 EAQ84920.1 - 5.1e-19 68.4 0.0 6.9e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 EAQ84920.1 - 3.6e-06 26.2 0.0 4.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.10 EAQ84920.1 - 7e-05 22.7 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Sugar_tr PF00083.19 EAQ84921.1 - 3e-28 98.6 35.0 5.4e-19 68.0 8.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ84921.1 - 6.4e-16 58.0 48.5 1.6e-12 46.8 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPT PF03151.11 EAQ84921.1 - 0.00069 19.2 1.0 0.00069 19.2 0.7 2.7 3 0 0 3 3 3 1 Triose-phosphate Transporter family p450 PF00067.17 EAQ84922.1 - 1.3e-39 136.0 0.0 3.2e-39 134.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EAQ84923.1 - 2.2e-05 24.0 0.4 2.2e-05 24.0 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAQ84923.1 - 0.0034 16.9 1.6 0.0041 16.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain FBPase PF00316.15 EAQ84924.1 - 3.9e-123 410.4 0.0 4.4e-123 410.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase NdhM PF10664.4 EAQ84924.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Thiolase_N PF00108.18 EAQ84925.1 - 4.9e-77 258.4 5.0 6.8e-77 258.0 3.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAQ84925.1 - 4.2e-37 126.2 0.0 9.7e-37 125.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EAQ84925.1 - 0.33 10.3 6.5 0.067 12.6 0.4 2.5 2 1 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain DUF4537 PF15057.1 EAQ84927.1 - 0.04 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) AKNA PF12443.3 EAQ84927.1 - 0.095 12.7 0.4 0.3 11.1 0.3 1.8 1 0 0 1 1 1 0 AT-hook-containing transcription factor HR1 PF02185.11 EAQ84927.1 - 0.23 11.2 2.6 0.74 9.5 1.8 1.9 1 1 0 1 1 1 0 Hr1 repeat AAA_31 PF13614.1 EAQ84928.1 - 1.9e-07 31.1 0.0 2.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EAQ84928.1 - 5.1e-07 29.2 0.0 5.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EAQ84928.1 - 0.00053 19.1 0.0 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EAQ84928.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 EAQ84928.1 - 0.036 13.4 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 YhjQ protein ArsA_ATPase PF02374.10 EAQ84928.1 - 0.084 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase ArgK PF03308.11 EAQ84928.1 - 0.1 11.3 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 ArgK protein AATF-Che1 PF13339.1 EAQ84929.1 - 4.7e-33 114.1 0.3 4.7e-33 114.1 0.2 3.3 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EAQ84929.1 - 3.5e-32 110.3 0.1 1.5e-31 108.3 0.1 2.2 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Pro_CA PF00484.14 EAQ84930.1 - 3.6e-46 156.9 0.7 4.3e-46 156.6 0.5 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Lipase_3 PF01764.20 EAQ84930.1 - 0.079 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_L7Ae PF01248.21 EAQ84931.1 - 3.9e-21 74.3 0.7 7.2e-21 73.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.15 EAQ84932.1 - 3e-18 65.9 0.0 4.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EAQ84932.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EAQ84932.1 - 0.0098 14.4 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 EAQ84932.1 - 0.019 14.4 2.4 0.019 14.4 1.7 3.3 3 0 0 3 3 3 0 RecR protein MOZ_SAS PF01853.13 EAQ84933.1 - 4.5e-79 264.0 0.1 6.3e-79 263.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family ENTH PF01417.15 EAQ84934.1 - 1.5e-38 131.5 0.7 2.4e-38 130.7 0.5 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EAQ84934.1 - 3.5e-08 33.3 43.2 3.5e-08 33.3 29.9 5.4 3 2 0 3 3 3 1 Domain of unknown function (DUF1720) DUF4264 PF14084.1 EAQ84934.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 EAQ84934.1 - 0.031 13.8 0.6 0.031 13.8 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Nup96 PF12110.3 EAQ84935.1 - 7.9e-68 228.6 0.0 1.2e-67 228.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EAQ84935.1 - 7.5e-44 148.9 0.0 1.2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EAQ84935.1 - 1.4e-20 73.6 173.0 8.7e-13 48.4 28.3 11.7 5 2 7 12 12 12 5 Nucleoporin FG repeat region UCH_1 PF13423.1 EAQ84938.1 - 9.7e-35 120.4 0.0 1.7e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EAQ84938.1 - 1.1e-25 90.8 0.0 1.9e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EAQ84938.1 - 4.5e-05 22.7 0.0 0.0015 17.7 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.22 EAQ84939.1 - 1.3e-53 178.6 3.5 4.5e-18 64.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 EAQ84940.1 - 3.8e-20 72.4 4.1 4.5e-19 68.9 2.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ84940.1 - 2.7e-16 60.0 0.0 1.2e-15 57.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ84940.1 - 2e-08 34.0 1.3 2e-08 34.0 0.9 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EAQ84940.1 - 0.08 13.0 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GTP_EFTU PF00009.22 EAQ84941.1 - 3.9e-44 150.3 0.0 6.9e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAQ84941.1 - 2.2e-20 72.6 0.1 7.8e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAQ84941.1 - 1.4e-07 31.4 0.7 4e-07 30.0 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAQ84941.1 - 7.2e-05 22.7 0.0 0.00023 21.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ84941.1 - 0.039 14.4 0.0 0.32 11.4 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EAQ84941.1 - 0.074 11.7 0.6 0.14 10.8 0.3 1.5 1 1 0 1 1 1 0 G-protein alpha subunit Med15 PF09606.5 EAQ84941.1 - 0.95 7.5 36.9 1.4 7.0 25.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ran-binding PF05508.6 EAQ84942.1 - 1.5e-109 365.5 0.0 2.3e-109 364.9 0.0 1.3 1 0 0 1 1 1 1 RanGTP-binding protein ING PF12998.2 EAQ84942.1 - 0.07 13.4 0.1 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Nop14 PF04147.7 EAQ84942.1 - 6.1 4.6 12.3 9.7 3.9 8.5 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EAQ84943.1 - 2.4e-29 102.1 45.4 3.5e-29 101.6 30.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EAQ84943.1 - 0.45 10.9 6.6 0.24 11.8 0.3 3.3 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SNF2_N PF00176.18 EAQ84946.1 - 4.3e-73 245.7 0.5 2.1e-66 223.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ84946.1 - 5.5e-10 38.9 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 EAQ84946.1 - 0.00012 20.9 0.0 0.00059 18.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 DEAD_2 PF06733.10 EAQ84946.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Surp PF01805.15 EAQ84951.1 - 3e-17 62.0 0.0 5.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Surp module DAO PF01266.19 EAQ84952.1 - 1.3e-37 129.5 0.1 1.8e-37 129.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EAQ84952.1 - 0.0023 16.8 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EAQ84952.1 - 0.0036 17.1 0.2 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding TBP PF00352.16 EAQ84953.1 - 2.2e-33 113.4 0.0 2.4e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EAQ84953.1 - 0.062 13.3 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) ETF_QO PF05187.8 EAQ84955.1 - 7.7e-46 154.6 0.0 1.4e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EAQ84955.1 - 7e-08 31.7 0.3 0.00014 20.8 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ84955.1 - 2.5e-07 30.6 0.1 8.8e-07 28.8 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EAQ84955.1 - 1.7e-05 24.1 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ84955.1 - 4.6e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ84955.1 - 0.00016 20.3 0.3 0.00023 19.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EAQ84955.1 - 0.00029 20.0 0.0 0.0073 15.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EAQ84955.1 - 0.00051 19.0 0.5 0.0025 16.7 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EAQ84955.1 - 0.00053 19.1 0.1 0.0011 18.0 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EAQ84955.1 - 0.0008 19.2 0.1 0.0034 17.1 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EAQ84955.1 - 0.0013 17.5 0.0 0.28 9.7 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Fer4_7 PF12838.2 EAQ84955.1 - 0.0024 18.2 1.1 0.0074 16.6 0.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.1 EAQ84955.1 - 0.0049 16.9 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ84955.1 - 0.0077 15.1 0.2 0.023 13.6 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EAQ84955.1 - 0.02 15.2 0.1 4.9 7.6 0.1 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ84955.1 - 0.078 11.8 0.4 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CorA PF01544.13 EAQ84956.1 - 7.7e-12 44.8 4.2 7.7e-12 44.8 2.9 2.2 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2232 PF09991.4 EAQ84956.1 - 0.34 9.8 5.1 0.25 10.2 1.7 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) Not1 PF04054.10 EAQ84957.1 - 7.7e-107 357.4 0.0 2.1e-106 356.0 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EAQ84957.1 - 2.6e-48 163.4 1.8 8.2e-48 161.8 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) ECH_C PF13766.1 EAQ84957.1 - 0.072 13.2 0.6 1 9.5 0.3 2.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Methyltransf_23 PF13489.1 EAQ84959.1 - 2.8e-09 36.9 0.0 9.8e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84959.1 - 0.0021 18.5 0.0 2.4 8.6 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ84959.1 - 0.0067 16.8 0.0 8.9 6.8 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ84959.1 - 0.083 13.4 0.0 0.98 10.0 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain UPF0029 PF01205.14 EAQ84960.1 - 2.6e-24 85.0 0.0 5.5e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PASTA PF03793.14 EAQ84960.1 - 0.042 13.4 0.3 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 PASTA domain FCH PF00611.18 EAQ84961.1 - 1e-21 76.9 0.0 3.5e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EAQ84961.1 - 7.6e-14 50.8 0.0 1.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ84961.1 - 4.6e-12 45.2 0.0 4.2e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EAQ84961.1 - 7.7e-11 41.4 0.0 1.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Seipin PF06775.9 EAQ84962.1 - 6.2e-37 127.0 0.0 9.3e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Glypican PF01153.14 EAQ84962.1 - 0.043 12.4 0.6 0.054 12.0 0.4 1.1 1 0 0 1 1 1 0 Glypican NTF2 PF02136.15 EAQ84963.1 - 3e-16 59.8 0.0 5.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain EthD PF07110.6 EAQ84964.1 - 2.6e-18 66.7 0.0 6.6e-17 62.2 0.0 2.2 1 1 0 1 1 1 1 EthD domain Methyltransf_12 PF08242.7 EAQ84965.1 - 2.6e-06 27.8 0.0 1.1e-05 25.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ84965.1 - 0.00088 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPPII_N PF12583.3 EAQ84965.1 - 0.2 11.7 0.0 0.97 9.5 0.0 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Cg6151-P PF10233.4 EAQ84966.1 - 3e-40 136.7 12.5 3.5e-40 136.5 8.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Picorna_P3A PF06363.6 EAQ84966.1 - 0.1 12.5 0.4 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Picornaviridae P3A protein DUF2207 PF09972.4 EAQ84966.1 - 0.45 9.0 6.3 0.58 8.6 4.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) LMF1 PF06762.9 EAQ84966.1 - 1.8 7.2 4.9 2.3 6.9 3.4 1.1 1 0 0 1 1 1 0 Lipase maturation factor PRA1 PF03208.14 EAQ84966.1 - 8.8 5.6 11.9 14 5.0 8.2 1.4 1 0 0 1 1 1 0 PRA1 family protein DUF3210 PF11489.3 EAQ84967.1 - 2.4e-243 810.0 83.7 2.4e-243 810.0 58.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Gryzun PF07919.7 EAQ84968.1 - 1e-108 364.1 0.0 1.2e-108 363.8 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EAQ84968.1 - 1.4e-85 286.7 1.9 4.3e-82 275.2 2.0 2.1 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EAQ84968.1 - 0.025 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking AAA_12 PF13087.1 EAQ84969.1 - 4.1e-51 173.2 0.0 7.3e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.6 EAQ84969.1 - 2.6e-30 105.3 0.3 3.7e-25 88.4 0.0 2.4 1 1 1 2 2 2 2 DNA replication factor Dna2 AAA_11 PF13086.1 EAQ84969.1 - 7.8e-26 91.0 0.1 4.6e-20 72.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain Cas_Cas4 PF01930.12 EAQ84969.1 - 5e-05 23.2 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF83 zf-primase PF09329.6 EAQ84970.1 - 3.8e-18 64.8 1.4 6.5e-18 64.0 1.0 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EAQ84970.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.5 EAQ84971.1 - 1.6e-78 263.9 3.6 4.1e-77 259.3 2.5 2.2 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DASH_Duo1 PF08651.5 EAQ84972.1 - 5.2e-33 112.4 0.2 8e-33 111.8 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.9 EAQ84972.1 - 0.029 13.2 3.4 0.04 12.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Syntaxin-6_N PF09177.6 EAQ84972.1 - 1.3 9.4 5.7 3.3 8.1 3.9 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF802 PF05650.6 EAQ84972.1 - 2.3 8.3 8.0 11 6.2 3.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF802) TTL PF03133.10 EAQ84974.1 - 3e-51 174.0 0.0 4.9e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EAQ84974.1 - 6.5e-41 139.8 0.0 4.4e-40 137.1 0.0 2.2 2 1 0 2 2 2 1 Survival protein SurE ATP-grasp_4 PF13535.1 EAQ84974.1 - 0.0063 16.2 0.0 0.043 13.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EAQ84974.1 - 0.0084 14.9 0.0 0.033 12.9 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.1 EAQ84974.1 - 0.02 15.0 0.2 0.064 13.3 0.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Menin PF05053.8 EAQ84974.1 - 0.32 9.0 0.4 0.57 8.2 0.3 1.3 1 0 0 1 1 1 0 Menin Nro1 PF12753.2 EAQ84974.1 - 4 6.2 7.0 5 5.9 4.3 1.5 1 1 0 1 1 1 0 Nuclear pore complex subunit Nro1 E1-E2_ATPase PF00122.15 EAQ84976.1 - 4.2e-56 189.5 2.0 4.2e-56 189.5 1.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ84976.1 - 5e-30 105.5 0.0 3.5e-29 102.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ84976.1 - 4.6e-20 71.3 0.0 1.1e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAQ84976.1 - 1.1e-18 68.1 0.0 1.9e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EAQ84976.1 - 9.9e-08 31.7 6.0 1e-07 31.6 0.2 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EAQ84976.1 - 3.7e-07 29.9 0.5 3.1e-06 26.9 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAQ84976.1 - 5.7e-06 25.7 0.9 0.00019 20.8 0.0 3.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus DUF2976 PF11190.3 EAQ84976.1 - 0.00027 20.3 8.4 0.048 13.1 0.3 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2976) YjgP_YjgQ PF03739.9 EAQ84976.1 - 0.0038 16.0 3.3 0.0083 14.9 2.0 1.7 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family Cortexin PF11057.3 EAQ84976.1 - 0.0045 16.5 0.9 4.5 6.9 0.0 3.0 3 0 0 3 3 3 2 Cortexin of kidney DUF3500 PF12006.3 EAQ84976.1 - 0.054 12.4 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF202 PF02656.10 EAQ84976.1 - 0.069 13.3 0.9 0.41 10.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Transposase_20 PF02371.11 EAQ84976.1 - 0.079 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Cation_ATPase_C PF00689.16 EAQ84977.1 - 1.8e-05 24.3 1.3 3.2e-05 23.5 0.9 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF2910 PF11139.3 EAQ84977.1 - 0.099 11.7 2.1 0.2 10.7 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) SIR2 PF02146.12 EAQ84978.1 - 1.7e-58 197.2 0.0 2.4e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EAQ84978.1 - 3.5e-05 23.4 0.0 6.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EAQ84978.1 - 0.0081 15.9 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2360 PF10152.4 EAQ84978.1 - 0.021 15.0 1.5 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 EAQ84979.1 - 1.5e-11 43.9 0.0 2.2e-07 30.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ84979.1 - 0.002 17.2 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PSDC PF12588.3 EAQ84979.1 - 0.065 12.8 0.1 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Phophatidylserine decarboxylase Aminotran_4 PF01063.14 EAQ84980.1 - 3.4e-29 101.9 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ESSS PF10183.4 EAQ84981.1 - 1.7e-27 95.8 0.6 2e-27 95.6 0.4 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Piwi PF02171.12 EAQ84982.1 - 6.6e-74 248.6 0.0 9.8e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EAQ84982.1 - 1.2e-08 34.1 0.0 2.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PEMT PF04191.8 EAQ84983.1 - 7.5e-30 103.1 3.5 1.1e-29 102.6 2.4 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EAQ84983.1 - 0.12 12.0 0.6 0.34 10.6 0.1 1.8 1 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EAQ84983.1 - 0.24 11.5 1.2 0.57 10.4 0.1 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Spermine_synth PF01564.12 EAQ84984.1 - 1.2e-07 30.9 0.0 1.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EAQ84984.1 - 5.5e-06 26.3 0.2 1.4e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ84984.1 - 0.00012 21.8 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ84984.1 - 0.0017 18.9 0.0 0.0034 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ84984.1 - 0.028 14.8 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 EAQ84984.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pyridox_ox_2 PF12900.2 EAQ84985.1 - 5.2e-27 94.4 0.0 8.4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyr_redox_2 PF07992.9 EAQ84987.1 - 3.2e-31 108.7 0.0 9.6e-31 107.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.17 EAQ84987.1 - 8.9e-30 103.1 0.0 2.5e-29 101.6 0.0 1.8 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.22 EAQ84987.1 - 1.8e-15 57.0 7.7 8e-15 55.0 0.6 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EAQ84987.1 - 1.4e-14 53.6 0.0 3.8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 EAQ84987.1 - 2.7e-14 52.9 1.6 1.4e-12 47.4 2.4 2.4 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 EAQ84987.1 - 2.9e-10 39.5 0.0 6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EAQ84987.1 - 1.2e-05 25.4 0.6 0.013 15.5 0.1 3.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ84987.1 - 2.1e-05 23.6 8.5 0.0055 15.6 0.1 4.8 4 1 1 5 5 5 2 FAD dependent oxidoreductase Rieske PF00355.21 EAQ84987.1 - 6.5e-05 22.4 0.0 0.00033 20.1 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.1 EAQ84987.1 - 0.00015 21.5 1.7 0.81 9.4 0.0 3.8 2 2 2 4 4 4 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EAQ84987.1 - 0.0057 16.8 0.9 0.083 13.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.1 EAQ84987.1 - 0.0066 15.3 0.0 0.039 12.8 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAQ84987.1 - 0.14 12.1 1.0 0.77 9.8 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Na_H_Exchanger PF00999.16 EAQ84988.1 - 7.8e-54 182.6 38.6 7.9e-29 100.3 6.8 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DUF824 PF05688.6 EAQ84989.1 - 6.5e-07 28.8 34.3 2 8.1 0.4 7.5 7 0 0 7 7 7 7 Salmonella repeat of unknown function (DUF824) Peptidase_S8 PF00082.17 EAQ84991.1 - 7.8e-12 44.9 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Rcd1 PF04078.8 EAQ84993.1 - 3e-74 249.1 2.7 7.8e-64 215.0 0.3 2.1 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like Opi1 PF08618.5 EAQ84993.1 - 0.0029 16.6 2.2 0.0042 16.0 1.5 1.1 1 0 0 1 1 1 1 Transcription factor Opi1 Proteasom_PSMB PF10508.4 EAQ84993.1 - 0.026 12.8 0.1 0.038 12.2 0.1 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Ceramidase_alk PF04734.8 EAQ84994.1 - 2e-237 789.3 0.0 1e-221 737.4 0.0 2.6 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase Amidohydro_5 PF13594.1 EAQ84995.1 - 7.2e-06 25.7 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EAQ84995.1 - 0.0042 17.1 0.0 0.0071 16.4 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Glyco_hydro_3 PF00933.16 EAQ84996.1 - 2.4e-52 177.7 0.0 3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Hexokinase_1 PF00349.16 EAQ84998.1 - 3.4e-15 55.9 0.0 4.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF2014 PF09427.5 EAQ84999.1 - 3.3e-116 386.9 2.5 4.7e-116 386.4 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EAQ84999.1 - 2.5e-06 27.1 2.5 4.5e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Nnf1 PF03980.9 EAQ84999.1 - 0.24 11.4 1.6 3 7.8 0.5 2.8 3 0 0 3 3 3 0 Nnf1 Cucumo_2B PF03263.8 EAQ85000.1 - 0.037 14.3 0.1 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B DUF4633 PF15464.1 EAQ85000.1 - 0.18 11.6 1.9 0.2 11.4 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Uteroglobin PF01099.12 EAQ85001.1 - 0.047 13.4 0.2 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Uteroglobin family CcmD PF04995.9 EAQ85001.1 - 1.3 8.8 2.9 0.66 9.7 0.2 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) PhoD PF09423.5 EAQ85002.1 - 8.9e-149 495.8 4.0 1e-148 495.6 2.8 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EAQ85002.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ85002.1 - 0.061 12.7 0.3 0.061 12.7 0.2 1.8 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase Ank_2 PF12796.2 EAQ85003.1 - 3.6e-100 328.4 20.9 2.1e-16 60.0 0.2 10.3 7 3 2 10 10 10 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ85003.1 - 1.7e-85 276.8 46.2 3.8e-08 32.7 0.1 19.5 19 0 0 19 19 19 16 Ankyrin repeat Ank_4 PF13637.1 EAQ85003.1 - 1.4e-70 232.4 26.4 1.8e-11 44.2 0.1 12.8 11 3 3 14 14 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85003.1 - 1.2e-62 201.5 33.5 6e-06 25.9 0.0 19.0 18 0 0 18 18 18 10 Ankyrin repeat Ank_5 PF13857.1 EAQ85003.1 - 2.9e-60 198.9 35.0 2.7e-09 36.9 0.3 14.2 9 3 6 15 15 15 12 Ankyrin repeats (many copies) Amino_oxidase PF01593.19 EAQ85003.1 - 2.9e-31 109.0 0.1 1.2e-17 64.1 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ85003.1 - 1e-11 44.6 0.9 4.3e-11 42.6 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AAA_16 PF13191.1 EAQ85003.1 - 1.3e-07 31.7 0.5 1.6e-06 28.2 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ85003.1 - 1.7e-07 31.4 0.0 7e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain DAO PF01266.19 EAQ85003.1 - 5.8e-05 22.1 0.2 0.00017 20.5 0.1 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase NACHT PF05729.7 EAQ85003.1 - 7.7e-05 22.4 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain FAD_binding_3 PF01494.14 EAQ85003.1 - 0.00018 20.6 1.9 0.00046 19.3 1.3 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EAQ85003.1 - 0.00038 19.4 0.3 0.00073 18.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EAQ85003.1 - 0.00057 19.0 0.8 0.0011 18.1 0.6 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EAQ85003.1 - 0.0034 15.9 0.5 0.052 12.0 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein AAA PF00004.24 EAQ85003.1 - 0.016 15.4 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pyr_redox PF00070.22 EAQ85003.1 - 0.017 15.5 3.2 0.028 14.8 0.8 2.5 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ85003.1 - 0.02 14.9 0.0 0.086 12.8 0.0 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ85003.1 - 0.025 13.6 1.1 0.053 12.6 0.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF2075 PF09848.4 EAQ85003.1 - 0.098 11.6 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pyr_redox_2 PF07992.9 EAQ85003.1 - 0.1 12.4 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ85003.1 - 0.13 11.1 0.5 0.23 10.3 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A RNA_helicase PF00910.17 EAQ85003.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ARGLU PF15346.1 EAQ85004.1 - 0.0065 16.2 14.4 0.01 15.6 10.0 1.2 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 CDC37_N PF03234.9 EAQ85004.1 - 0.02 15.2 0.6 0.028 14.7 0.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 EAQ85004.1 - 0.023 13.7 3.5 0.032 13.2 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EAQ85004.1 - 0.025 11.9 4.0 0.032 11.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF874 PF05917.6 EAQ85004.1 - 0.032 13.0 3.4 0.044 12.6 2.3 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF612 PF04747.7 EAQ85004.1 - 0.043 12.7 7.6 0.056 12.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Atg14 PF10186.4 EAQ85004.1 - 0.13 11.1 3.3 0.2 10.5 2.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1675 PF07897.6 EAQ85004.1 - 0.23 11.2 4.3 0.4 10.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PGBA_C PF15437.1 EAQ85004.1 - 1.1 9.4 21.6 12 6.1 15.0 2.1 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF4337 PF14235.1 EAQ85004.1 - 4.9 6.9 6.0 7.4 6.3 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BNR_2 PF13088.1 EAQ85006.1 - 6.7e-31 107.5 0.4 8.5e-31 107.2 0.3 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.1 EAQ85006.1 - 6.3e-09 35.3 0.0 8.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain UvrD_C PF13361.1 EAQ85007.1 - 3.1e-75 253.8 0.0 4.7e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EAQ85007.1 - 2.1e-61 207.9 0.2 7.8e-60 202.7 0.1 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EAQ85007.1 - 1.2e-13 51.0 0.0 3.2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ85007.1 - 7.2e-12 44.8 0.3 2.9e-11 42.9 0.2 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAQ85007.1 - 4.6e-06 26.3 0.2 0.00052 19.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EAQ85007.1 - 2.1e-05 24.1 0.0 0.22 10.9 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EAQ85007.1 - 0.00019 20.8 0.0 0.0097 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mucin PF01456.12 EAQ85008.1 - 0.011 15.4 6.1 0.014 15.1 4.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Staphylcoagulse PF04022.7 EAQ85008.1 - 6.9 6.1 14.3 1.8 8.0 6.6 2.3 1 1 1 2 2 2 0 Staphylocoagulase repeat Pkinase PF00069.20 EAQ85009.1 - 9.1e-22 77.4 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85009.1 - 1.5e-10 40.5 0.0 1.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ85009.1 - 0.0039 16.9 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ85009.1 - 0.03 13.9 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EAQ85009.1 - 0.037 13.1 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 EAQ85009.1 - 0.088 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1604 PF07713.8 EAQ85010.1 - 8.7e-33 111.9 1.9 3.8e-32 109.9 1.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EAQ85010.1 - 4.3e-08 32.8 0.3 3.4e-07 29.9 0.2 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EAQ85010.1 - 0.00093 18.9 1.4 0.0024 17.6 0.1 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site DHDPS PF00701.17 EAQ85012.1 - 1.5e-13 50.0 0.0 1.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family WD40 PF00400.27 EAQ85014.1 - 2.4e-48 160.3 21.1 5.5e-12 45.0 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EAQ85014.1 - 2.1e-06 27.5 11.3 0.012 15.3 0.3 4.1 1 1 3 5 5 5 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EAQ85014.1 - 0.028 14.2 0.0 6.4 6.6 0.0 3.4 4 0 0 4 4 4 0 YmzC-like protein Terpene_synth_C PF03936.11 EAQ85016.1 - 7.6e-07 28.6 0.0 1.2e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DOPA_dioxygen PF08883.6 EAQ85018.1 - 1.8e-30 105.0 0.0 5e-30 103.6 0.0 1.6 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family Podoplanin PF05808.6 EAQ85019.1 - 0.0066 16.0 0.3 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 Podoplanin TPR_MLP1_2 PF07926.7 EAQ85020.1 - 6.8e-29 100.2 29.5 6.8e-29 100.2 20.5 17.7 6 5 8 15 15 15 4 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EAQ85021.1 - 0.013 15.4 2.2 0.032 14.1 0.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor YopE_N PF09020.5 EAQ85021.1 - 0.022 14.8 0.3 0.022 14.8 0.2 2.2 2 0 0 2 2 2 0 YopE, N terminal Tubulin_C PF03953.12 EAQ85025.1 - 2.5e-49 166.4 0.1 3.8e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 EAQ85025.1 - 3.3e-48 164.3 0.0 6.1e-48 163.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 EAQ85025.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.22 EAQ85026.1 - 5.8e-49 165.9 0.7 7.7e-23 81.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EAQ85026.1 - 3.1e-19 68.6 7.6 3.1e-19 68.6 5.3 4.2 4 1 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 EAQ85026.1 - 9.9e-18 65.0 0.2 6e-05 23.1 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EAQ85026.1 - 1.8e-10 40.4 6.0 0.00081 18.6 0.0 4.6 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EAQ85026.1 - 1.4e-08 35.6 0.3 0.0076 17.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EAQ85026.1 - 9e-08 31.5 5.2 0.14 11.2 0.1 4.4 4 2 0 4 4 4 3 AAA ATPase domain Miro PF08477.8 EAQ85026.1 - 3.5e-07 30.7 0.3 0.0064 16.9 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 EAQ85026.1 - 2.6e-06 26.8 0.1 0.061 12.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EAQ85026.1 - 4.2e-06 27.1 0.5 0.22 11.8 0.0 3.7 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 EAQ85026.1 - 9.2e-06 24.9 0.0 0.13 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ85026.1 - 1e-05 25.5 0.3 0.0088 16.0 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EAQ85026.1 - 1.1e-05 25.3 0.0 0.061 13.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EAQ85026.1 - 3.8e-05 24.0 19.5 0.0065 16.8 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.1 EAQ85026.1 - 7.6e-05 22.8 0.1 0.79 9.8 0.0 3.2 2 2 0 2 2 2 2 AAA domain MobB PF03205.9 EAQ85026.1 - 0.0001 22.0 0.4 0.35 10.5 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EAQ85026.1 - 0.00014 21.7 0.0 0.72 9.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EAQ85026.1 - 0.00018 21.5 1.7 0.095 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EAQ85026.1 - 0.00026 21.2 0.1 0.36 11.0 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EAQ85026.1 - 0.00084 19.0 0.3 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 EAQ85026.1 - 0.0021 17.9 0.1 0.96 9.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EAQ85026.1 - 0.0032 16.9 0.6 3.5 6.9 0.0 3.7 4 0 0 4 4 4 1 AAA-like domain ArgK PF03308.11 EAQ85026.1 - 0.0033 16.2 3.0 0.75 8.5 0.0 2.9 3 0 0 3 3 2 2 ArgK protein NTPase_1 PF03266.10 EAQ85026.1 - 0.0038 16.9 0.1 0.64 9.7 0.1 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 EAQ85026.1 - 0.0042 17.2 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 EAQ85026.1 - 0.0067 15.9 0.2 2.1 7.8 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EAQ85026.1 - 0.0086 15.9 8.8 0.58 9.9 0.1 4.3 4 1 0 4 4 4 1 Dynamin family NB-ARC PF00931.17 EAQ85026.1 - 0.013 14.3 0.0 5.4 5.7 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 EAQ85026.1 - 0.015 14.1 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EAQ85026.1 - 0.02 14.3 0.9 1.5 8.2 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EAQ85026.1 - 0.028 14.1 0.2 5.9 6.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EAQ85026.1 - 0.25 11.2 6.0 6.1 6.8 0.2 3.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit bZIP_1 PF00170.16 EAQ85028.1 - 4.5e-12 45.7 1.9 6.9e-12 45.1 1.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ85028.1 - 2.4e-06 27.2 5.2 4.1e-06 26.5 3.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper A_deaminase PF00962.17 EAQ85029.1 - 6e-35 120.7 0.1 9.8e-32 110.1 0.0 2.5 2 1 0 2 2 2 2 Adenosine/AMP deaminase SRP40_C PF05022.7 EAQ85030.1 - 2.9e-25 88.5 1.2 2.9e-25 88.5 0.8 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain DUF1673 PF07895.6 EAQ85031.1 - 0.018 14.5 0.2 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Cg6151-P PF10233.4 EAQ85031.1 - 0.82 9.6 6.9 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P DUF1700 PF08006.6 EAQ85031.1 - 1.3 8.3 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF4191 PF13829.1 EAQ85031.1 - 4.4 6.3 5.9 6.3 5.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Tic20 PF09685.5 EAQ85031.1 - 6.5 6.7 10.9 3.1 7.8 1.1 2.2 2 0 0 2 2 2 0 Tic20-like protein Complex1_51K PF01512.12 EAQ85033.1 - 8.2e-49 165.1 0.0 1.4e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EAQ85033.1 - 1.5e-17 62.4 0.8 1.5e-17 62.4 0.5 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EAQ85033.1 - 2.3e-09 36.9 0.0 9.8e-09 34.9 0.0 2.2 3 0 0 3 3 3 1 SLBB domain Flavoprotein PF02441.14 EAQ85034.1 - 1.2e-17 63.8 0.0 1.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein DUF3431 PF11913.3 EAQ85035.1 - 2.2e-90 302.0 0.0 2.7e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Abhydrolase_4 PF08386.5 EAQ85038.1 - 3.8e-23 81.3 0.0 1.1e-22 79.8 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ85038.1 - 1.2e-15 57.7 0.0 1.2e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ85038.1 - 4.3e-08 33.3 0.1 2.2e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ85038.1 - 0.003 17.3 0.0 0.11 12.2 0.0 2.7 1 1 1 2 2 2 2 Alpha/beta hydrolase family Ank_2 PF12796.2 EAQ85039.1 - 5e-95 312.0 13.3 5.9e-14 52.1 0.0 10.6 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ85039.1 - 6e-67 220.1 19.7 5.9e-11 42.2 0.2 16.4 8 5 9 17 17 17 14 Ankyrin repeats (many copies) Ank PF00023.25 EAQ85039.1 - 8.1e-66 214.7 16.5 3.4e-05 23.4 0.0 18.7 19 0 0 19 19 19 16 Ankyrin repeat Ank_4 PF13637.1 EAQ85039.1 - 4.1e-62 205.5 15.1 5.9e-06 26.6 0.0 13.6 5 3 10 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85039.1 - 6.7e-54 174.4 12.0 0.0051 16.9 0.1 17.8 18 0 0 18 18 18 11 Ankyrin repeat Hira PF07569.6 EAQ85041.1 - 1.8e-85 285.5 0.0 3.4e-85 284.7 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EAQ85041.1 - 1.1e-38 129.6 21.5 7.2e-07 28.8 0.1 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 EAQ85041.1 - 9.7e-11 40.9 0.6 2e-10 39.9 0.4 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EAQ85041.1 - 0.00092 18.8 0.2 38 4.0 0.0 4.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EAQ85041.1 - 0.56 7.9 0.0 2.3 5.9 0.0 1.9 2 0 0 2 2 2 0 IKI3 family Peptidase_M24 PF00557.19 EAQ85043.1 - 5e-43 147.1 0.1 6.4e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1168 PF06658.7 EAQ85043.1 - 0.00069 19.1 3.9 0.0011 18.4 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) BLVR PF06375.6 EAQ85043.1 - 0.022 14.5 2.3 0.1 12.4 1.7 1.9 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) SBP56 PF05694.6 EAQ85044.1 - 0.0024 16.4 0.0 0.026 13.0 0.0 2.3 3 0 0 3 3 3 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EAQ85044.1 - 0.0024 17.0 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller NHL PF01436.16 EAQ85044.1 - 0.023 14.6 0.0 5 7.2 0.0 3.3 4 0 0 4 4 4 0 NHL repeat SGL PF08450.7 EAQ85044.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region FtsJ PF01728.14 EAQ85045.1 - 6.6e-61 205.4 0.0 8.6e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 EAQ85046.1 - 5.3e-40 136.6 0.0 8.9e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ85046.1 - 3e-14 52.6 0.0 6.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAQ85046.1 - 0.0013 17.5 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EAQ85046.1 - 0.069 13.2 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 EAQ85046.1 - 1.5 8.6 16.6 2.9 7.7 11.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EAQ85046.1 - 4.6 4.8 4.8 6.4 4.3 3.3 1.1 1 0 0 1 1 1 0 Ycf1 SOBP PF15279.1 EAQ85046.1 - 9.9 6.4 14.7 3.4 7.9 0.5 2.7 2 0 0 2 2 2 0 Sine oculis-binding protein CBM_1 PF00734.13 EAQ85047.1 - 2e-13 49.7 11.5 5.2e-13 48.3 8.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 EAQ85047.1 - 2.5e-10 38.5 40.4 0.15 11.9 0.1 10.7 10 0 0 10 10 10 6 BNR/Asp-box repeat His_Phos_2 PF00328.17 EAQ85048.1 - 7.9e-24 84.6 0.0 1.7e-23 83.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Stm1_N PF09598.5 EAQ85048.1 - 0.69 10.6 2.5 1.2 9.9 1.8 1.3 1 0 0 1 1 1 0 Stm1 Ank_2 PF12796.2 EAQ85049.1 - 1.1e-110 362.1 35.3 2.9e-23 82.0 0.6 7.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Glyco_hydro_2_C PF02836.12 EAQ85049.1 - 5.8e-101 337.3 0.0 8.6e-101 336.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ank PF00023.25 EAQ85049.1 - 2.3e-93 301.6 28.0 4.6e-08 32.4 0.0 13.8 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.1 EAQ85049.1 - 1.5e-80 264.2 23.7 7.1e-11 42.3 0.1 13.4 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85049.1 - 2.1e-58 188.4 15.6 0.00069 19.6 0.0 13.9 13 0 0 13 13 13 12 Ankyrin repeat Bgal_small_N PF02929.12 EAQ85049.1 - 6e-52 176.3 0.0 1e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Ank_5 PF13857.1 EAQ85049.1 - 1.2e-51 171.5 19.0 9.3e-08 32.0 0.1 8.5 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Glyco_hydro_2_N PF02837.13 EAQ85049.1 - 5.8e-45 152.8 0.0 9.2e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain PNP_UDP_1 PF01048.15 EAQ85049.1 - 1.8e-14 53.2 3.0 1.1e-13 50.6 0.1 2.9 2 1 0 2 2 2 1 Phosphorylase superfamily Glyco_hydro_2 PF00703.16 EAQ85049.1 - 6.3e-08 33.0 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 NACHT PF05729.7 EAQ85049.1 - 0.00021 20.9 0.0 0.00062 19.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ85049.1 - 0.022 14.8 0.0 0.075 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAQ85049.1 - 0.35 11.0 0.0 0.71 10.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Nse4-Nse3_bdg PF15412.1 EAQ85049.1 - 0.41 10.5 14.7 7.7 6.4 0.1 5.9 6 0 0 6 6 6 0 Binding domain of Nse4/EID3 to Nse3-MAGE DEAD PF00270.24 EAQ85052.1 - 4.8e-22 78.2 0.0 4.8e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ85052.1 - 4.2e-18 64.9 0.1 2e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ85052.1 - 0.00025 20.9 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAQ85052.1 - 0.0027 16.5 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rrf2 PF02082.15 EAQ85052.1 - 0.12 12.5 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator Mannosyl_trans2 PF04188.8 EAQ85054.1 - 1.2e-60 205.6 0.0 2.5e-60 204.6 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) YTH PF04146.10 EAQ85055.1 - 2.8e-06 26.9 0.1 0.018 14.6 0.0 2.4 1 1 1 2 2 2 2 YT521-B-like domain Glyco_hydro_61 PF03443.9 EAQ85056.1 - 3.4e-67 226.4 0.0 4.4e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MGC-24 PF05283.6 EAQ85056.1 - 3.5 7.3 8.6 6.2 6.5 5.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) CFEM PF05730.6 EAQ85057.1 - 1.8e-13 50.0 9.6 4.1e-13 48.9 6.7 1.6 1 0 0 1 1 1 1 CFEM domain RBP_receptor PF14752.1 EAQ85057.1 - 0.11 10.7 7.5 0.25 9.6 0.3 2.1 1 1 1 2 2 2 0 Retinol binding protein receptor FA_FANCE PF11510.3 EAQ85057.1 - 0.38 9.8 3.5 0.7 8.9 2.4 1.3 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE p450 PF00067.17 EAQ85058.1 - 1.1e-54 185.7 0.0 1.4e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transgly_assoc PF04226.8 EAQ85058.1 - 0.7 10.0 4.0 1.7 8.7 2.8 1.6 1 0 0 1 1 1 0 Transglycosylase associated protein MscS_TM PF12794.2 EAQ85059.1 - 0.28 9.7 7.4 0.061 11.9 0.3 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Velvet PF11754.3 EAQ85063.1 - 6.6e-52 176.0 0.6 1.6e-51 174.8 0.4 1.6 1 1 0 1 1 1 1 Velvet factor DRMBL PF07522.9 EAQ85065.1 - 5e-05 23.3 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.7 EAQ85065.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase p450 PF00067.17 EAQ85066.1 - 1.9e-30 105.7 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PT-TG PF14449.1 EAQ85066.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin TG Glyco_hydro_43 PF04616.9 EAQ85067.1 - 5.3e-62 209.5 6.0 6e-62 209.3 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF572 PF04502.8 EAQ85068.1 - 1.7e-51 175.3 0.0 2.3e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) UQ_con PF00179.21 EAQ85069.1 - 2.2e-33 114.6 0.0 2.7e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.10 EAQ85070.1 - 4.3e-105 350.5 0.2 5e-105 350.3 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EAQ85070.1 - 3.5e-10 39.4 0.4 1.3e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.8 EAQ85071.1 - 1.2e-26 92.7 0.0 1.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EAQ85071.1 - 0.00014 21.7 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HLH PF00010.21 EAQ85072.1 - 2.8e-14 52.5 0.5 9e-14 50.9 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Serine_rich PF08824.5 EAQ85072.1 - 0.095 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Serine rich protein interaction domain AMP_N PF05195.11 EAQ85073.1 - 2e-31 108.1 0.0 3.2e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 EAQ85073.1 - 1.6e-22 80.0 0.0 2.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Dfp1_Him1_M PF08630.5 EAQ85074.1 - 7.3e-40 135.6 0.0 1.3e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EAQ85074.1 - 2.4e-23 81.5 0.6 4.9e-23 80.5 0.4 1.5 1 0 0 1 1 1 1 DBF zinc finger GFO_IDH_MocA PF01408.17 EAQ85074.1 - 4.2e-12 46.6 0.0 8.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PTCB-BRCT PF12738.2 EAQ85074.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 EAQ85074.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DHDPS PF00701.17 EAQ85077.1 - 3.5e-40 137.4 0.0 5.2e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Tyrosinase PF00264.15 EAQ85078.1 - 2.6e-19 70.2 0.0 8.1e-19 68.6 0.0 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_16 PF00722.16 EAQ85079.1 - 4.3e-32 110.8 0.5 4.3e-32 110.8 0.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Mucin PF01456.12 EAQ85079.1 - 4 7.2 27.0 7.9 6.2 18.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SKG6 PF08693.5 EAQ85080.1 - 8.2e-14 50.6 6.6 1.8e-13 49.5 4.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EAQ85080.1 - 0.0039 16.8 0.0 0.0055 16.4 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 EAQ85080.1 - 0.0066 15.9 0.0 0.02 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) RXT2_N PF08595.6 EAQ85081.1 - 2.2e-11 43.7 9.8 5.7e-07 29.4 0.1 3.1 3 1 0 4 4 4 2 RXT2-like, N-terminal MFS_1 PF07690.11 EAQ85082.1 - 2.3e-36 125.2 64.2 3.4e-36 124.6 41.8 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EAQ85083.1 - 8.7e-24 83.7 0.0 1.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ85083.1 - 0.03 14.2 2.1 0.06 13.2 1.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Chordopox_A13L PF05961.6 EAQ85083.1 - 0.26 11.2 0.0 0.54 10.2 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Acetyltransf_7 PF13508.1 EAQ85084.1 - 1.4e-08 34.7 0.0 5.4e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ85084.1 - 8.9e-08 32.0 0.0 2.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAQ85084.1 - 3.9e-06 26.9 0.0 7.6e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 EAQ85084.1 - 9.2e-05 21.2 2.2 0.00013 20.6 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_9 PF13527.1 EAQ85084.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ85084.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein TctC PF03401.9 EAQ85084.1 - 0.022 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Acetyltransf_CG PF14542.1 EAQ85084.1 - 0.029 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short PF00106.20 EAQ85086.1 - 0.013 15.4 0.0 0.57 10.0 0.0 2.6 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.11 EAQ85087.1 - 1.7e-22 79.6 36.7 1.7e-22 79.6 25.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ85087.1 - 0.0093 15.7 0.1 0.033 13.9 0.1 1.9 1 0 0 1 1 1 1 MFS_1 like family UCR_hinge PF02320.11 EAQ85088.1 - 7.4e-29 99.4 6.4 1.9e-28 98.1 4.4 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF1510 PF07423.6 EAQ85088.1 - 0.25 10.6 21.0 0.3 10.4 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 EAQ85088.1 - 2 7.1 14.9 2.4 6.8 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RRN3 PF05327.6 EAQ85088.1 - 2.2 6.2 8.3 2.6 6.0 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Asp-B-Hydro_N PF05279.6 EAQ85088.1 - 2.5 7.9 25.4 2.9 7.6 17.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APG6 PF04111.7 EAQ85088.1 - 3.7 6.5 11.3 3.8 6.4 7.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SAPS PF04499.10 EAQ85088.1 - 3.8 6.0 10.0 4.2 5.8 6.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.9 EAQ85088.1 - 3.8 6.9 15.3 5.7 6.4 10.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 EAQ85088.1 - 4.2 6.7 19.2 5.3 6.4 13.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 EAQ85088.1 - 4.4 7.0 8.2 5.6 6.6 5.7 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.2 EAQ85088.1 - 6.2 4.3 8.0 6.6 4.2 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 EAQ85088.1 - 6.7 6.5 5.8 7.7 6.3 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Daxx PF03344.10 EAQ85088.1 - 6.8 5.0 25.5 7.7 4.8 17.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF4045 PF13254.1 EAQ85088.1 - 9.1 5.4 13.8 11 5.2 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 EAQ85088.1 - 9.4 4.1 12.6 9.7 4.0 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein WWbp PF10349.4 EAQ85089.1 - 2.5e-16 60.5 12.3 3.7e-16 60.0 8.5 1.2 1 0 0 1 1 1 1 WW-domain ligand protein Phage_Mu_Gp45 PF06890.7 EAQ85089.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein DUF605 PF04652.11 EAQ85089.1 - 1.2 8.4 17.7 1.4 8.2 12.2 1.1 1 0 0 1 1 1 0 Vta1 like Drf_GBD PF06371.8 EAQ85091.1 - 0.0016 17.7 0.1 0.013 14.8 0.1 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain UPF0561 PF10573.4 EAQ85091.1 - 0.012 15.4 1.2 0.12 12.2 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 Suc_Fer-like PF06999.7 EAQ85092.1 - 6e-20 72.2 0.2 2.4e-11 44.0 0.0 3.1 3 0 0 3 3 3 3 Sucrase/ferredoxin-like CobT PF06213.7 EAQ85092.1 - 8.7 5.3 9.1 13 4.8 6.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Acyltransferase PF01553.16 EAQ85093.1 - 1.2e-09 37.7 0.0 9.7e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase BRAP2 PF07576.7 EAQ85094.1 - 9.2e-21 73.4 0.0 1.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EAQ85094.1 - 1.1e-16 60.7 9.1 3.4e-16 59.0 6.3 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EAQ85094.1 - 4e-09 36.1 10.1 4e-09 36.1 7.0 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EAQ85094.1 - 1.8e-05 24.3 7.7 1.8e-05 24.3 5.3 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAQ85094.1 - 0.00031 20.3 8.3 0.00082 18.9 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ85094.1 - 0.003 17.1 6.9 0.003 17.1 4.8 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ85094.1 - 0.003 17.5 8.7 0.003 17.5 6.0 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAQ85094.1 - 0.008 16.2 6.0 0.008 16.2 4.2 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger SBDS_C PF09377.5 EAQ85094.1 - 0.0089 15.7 1.1 0.017 14.7 0.7 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain zf-RING_6 PF14835.1 EAQ85094.1 - 0.01 15.6 3.7 0.024 14.4 2.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein STAT_int PF02865.12 EAQ85094.1 - 0.032 14.1 1.1 0.067 13.1 0.7 1.4 1 0 0 1 1 1 0 STAT protein, protein interaction domain zf-RING_UBOX PF13445.1 EAQ85094.1 - 0.037 13.7 5.3 0.035 13.8 1.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EAQ85094.1 - 0.064 13.0 5.9 0.18 11.6 4.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_L11_N PF03946.9 EAQ85094.1 - 0.11 11.9 1.3 0.28 10.6 0.9 1.7 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain ubiquitin PF00240.18 EAQ85095.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EAQ85095.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAQ85095.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAQ85095.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAQ85095.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAQ85095.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EAQ85095.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EAQ85095.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EAQ85095.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EAQ85095.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EAQ85095.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EAQ85095.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EAQ85095.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EAQ85095.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EAQ85095.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EAQ85095.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EAQ85095.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EAQ85095.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EAQ85095.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EAQ85095.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EAQ85095.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Zn_clus PF00172.13 EAQ85096.1 - 0.0032 17.3 7.7 0.0067 16.3 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.16 EAQ85097.1 - 2.1e-33 113.5 25.1 4.7e-10 38.8 0.4 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAQ85097.1 - 7.4e-22 77.8 0.0 5.8e-14 52.4 0.0 4.1 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAQ85097.1 - 5.2e-05 23.2 0.0 0.0073 16.3 0.0 3.1 3 1 0 3 3 3 1 Prenyltransferase-like DND1_DSRM PF14709.1 EAQ85098.1 - 0.057 13.7 0.1 0.18 12.0 0.1 1.9 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 NTP_transferase PF00483.18 EAQ85100.1 - 4.1e-49 167.1 0.0 9e-49 166.0 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EAQ85100.1 - 1.4e-15 55.9 12.1 2.7e-09 36.1 1.2 4.2 1 1 4 5 5 5 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EAQ85100.1 - 6.2e-11 42.6 0.0 8.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EAQ85100.1 - 8.7e-07 28.3 0.9 8.7e-07 28.3 0.6 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase FGGY_C PF02782.11 EAQ85101.1 - 3.9e-75 251.8 0.4 7.3e-75 250.9 0.3 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAQ85101.1 - 1.3e-53 181.8 0.0 1.9e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Pkinase PF00069.20 EAQ85102.1 - 5.5e-27 94.5 0.0 1e-26 93.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85102.1 - 5.4e-16 58.4 0.0 5.6e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85102.1 - 0.0047 15.9 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Glyco_hydro_81 PF03639.8 EAQ85103.1 - 8.2e-109 364.5 0.0 2.6e-49 167.8 0.0 4.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 81 Tbf5 PF06331.7 EAQ85103.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Stn1 PF10451.4 EAQ85104.1 - 1.4e-13 50.3 0.6 2e-12 46.5 0.4 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EAQ85104.1 - 1.8e-06 27.7 0.2 6.1e-06 25.9 0.2 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain TOBE PF03459.12 EAQ85104.1 - 0.08 13.0 0.2 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 TOBE domain DnaJ PF00226.26 EAQ85105.1 - 2.9e-24 84.5 1.8 2.9e-24 84.5 1.2 2.2 2 0 0 2 2 2 1 DnaJ domain dCMP_cyt_deam_1 PF00383.17 EAQ85106.1 - 1.3e-14 53.6 0.0 2.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EAQ85106.1 - 0.018 14.7 0.1 0.034 13.8 0.0 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase BTG PF07742.7 EAQ85106.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 BTG family MR_MLE_C PF13378.1 EAQ85108.1 - 7.5e-20 70.9 0.2 3.5e-19 68.8 0.0 2.2 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EAQ85108.1 - 2.8e-12 46.9 0.0 8.8e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EAQ85108.1 - 0.00095 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EAQ85108.1 - 0.0099 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PHA_synth_III_E PF09712.5 EAQ85109.1 - 0.0096 15.3 0.1 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Rad10 PF03834.9 EAQ85110.1 - 1.9e-28 97.9 0.0 2.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EAQ85110.1 - 0.0087 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Glyco_hydro_47 PF01532.15 EAQ85111.1 - 2.3e-140 468.2 0.0 2.6e-140 468.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IATP PF04568.7 EAQ85112.1 - 0.03 14.3 2.8 0.038 14.0 1.9 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP XAP5 PF04921.9 EAQ85112.1 - 0.13 11.8 1.4 0.15 11.6 1.0 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Bac_small_YrzI PF09501.5 EAQ85112.1 - 1.1 9.1 5.0 0.15 11.9 0.7 1.5 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) TPPII_N PF12583.3 EAQ85112.1 - 4.2 7.4 7.7 4.8 7.3 5.3 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DEAD PF00270.24 EAQ85113.1 - 3.5e-42 143.7 0.1 5.3e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase GST_C PF00043.20 EAQ85113.1 - 4.9e-08 32.8 0.0 3.6e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAQ85113.1 - 9.5e-07 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ85113.1 - 5.6e-06 26.2 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAQ85113.1 - 9e-06 25.4 0.1 2.3e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAQ85113.1 - 2.4e-05 24.4 0.0 6.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ResIII PF04851.10 EAQ85113.1 - 3.6e-05 23.6 0.3 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAQ85113.1 - 4.3e-05 23.2 1.9 4.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GST_C_3 PF14497.1 EAQ85113.1 - 0.002 18.5 0.0 0.0072 16.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cas_Csa4 PF09703.5 EAQ85113.1 - 0.043 12.7 0.7 0.25 10.2 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) RRM_1 PF00076.17 EAQ85114.1 - 2.3e-21 75.2 0.1 1.4e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ85114.1 - 4.9e-18 64.8 0.0 4.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ85114.1 - 3.4e-11 42.8 0.0 8.8e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAQ85114.1 - 0.0079 16.0 0.0 0.018 14.8 0.0 1.5 2 0 0 2 2 2 1 RNA binding motif PXA PF02194.10 EAQ85115.1 - 1.1e-54 184.7 0.3 1.1e-54 184.7 0.2 2.4 3 0 0 3 3 3 1 PXA domain PX PF00787.19 EAQ85115.1 - 6.8e-16 58.0 2.7 1.9e-15 56.6 1.9 1.9 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.7 EAQ85115.1 - 1.9e-14 53.7 0.0 1.2e-13 51.1 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal RGS PF00615.14 EAQ85115.1 - 5.8e-06 26.3 0.0 2e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3505 PF12013.3 EAQ85116.1 - 3.6e-29 101.2 2.3 1.5e-28 99.2 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EAQ85116.1 - 3.6 8.0 5.1 2.7 8.3 0.1 3.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Fructosamin_kin PF03881.9 EAQ85117.1 - 8.2e-12 44.6 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase ADH_zinc_N PF00107.21 EAQ85117.1 - 1.9e-10 40.3 0.2 3.9e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ85117.1 - 2.8e-10 39.9 0.4 1.3e-09 37.7 0.3 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EAQ85117.1 - 0.022 15.6 0.0 0.049 14.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 EAQ85118.1 - 1.1e-10 41.7 0.0 5.5e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ85118.1 - 3.8e-06 26.7 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AstA PF04958.7 EAQ85118.1 - 0.0096 14.3 0.0 0.014 13.8 0.0 1.2 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Hydrolase_4 PF12146.3 EAQ85118.1 - 0.078 12.8 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase PTCB-BRCT PF12738.2 EAQ85119.1 - 3.8e-28 97.1 0.5 2.6e-18 65.6 0.1 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EAQ85119.1 - 1.2e-26 92.6 0.1 7.6e-09 35.5 0.0 5.7 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain HMG_CoA_synt_N PF01154.12 EAQ85120.1 - 1.7e-93 310.9 0.6 3.1e-93 310.1 0.4 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EAQ85120.1 - 3.7e-91 305.5 0.6 1.2e-89 300.5 0.4 2.3 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal BCS1_N PF08740.6 EAQ85121.1 - 2.3e-55 187.1 0.5 2.3e-55 187.1 0.3 2.6 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 EAQ85121.1 - 3.4e-09 36.9 0.0 8.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIF_alpha PF05793.7 EAQ85121.1 - 5.7e-05 21.6 38.0 5.7e-05 21.6 26.4 2.4 4 0 0 4 4 4 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_25 PF13481.1 EAQ85121.1 - 0.00028 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ85121.1 - 0.00059 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EAQ85121.1 - 0.0011 18.7 0.0 0.0039 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAQ85121.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAQ85121.1 - 0.0084 16.9 2.6 0.057 14.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EAQ85121.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ85121.1 - 0.062 13.0 0.1 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 EAQ85121.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain DNA_pol_viral_N PF00242.12 EAQ85121.1 - 0.54 9.2 16.2 1.4 7.8 11.2 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4569 PF15133.1 EAQ85121.1 - 2 7.7 14.3 7.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) AAA_13 PF13166.1 EAQ85121.1 - 2.9 6.2 29.5 6.7 5.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain MIP-T3 PF10243.4 EAQ85121.1 - 3 6.1 55.8 0.33 9.3 34.9 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EAQ85121.1 - 4.3 5.7 33.6 7.9 4.8 20.2 2.1 2 0 0 2 2 2 0 Daxx Family EBV-NA3 PF05009.7 EAQ85122.1 - 0.067 12.4 1.1 0.087 12.0 0.8 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nucleoplasmin PF03066.10 EAQ85122.1 - 0.21 11.1 0.7 0.27 10.7 0.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin UPF0560 PF10577.4 EAQ85122.1 - 0.36 9.0 1.8 0.46 8.6 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Methyltransf_23 PF13489.1 EAQ85125.1 - 3e-21 75.7 0.0 4.6e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85125.1 - 1.3e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85125.1 - 1.3e-14 54.7 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ85125.1 - 4.3e-14 52.3 0.0 6e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ85125.1 - 6.3e-13 49.0 0.0 9.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ85125.1 - 6.4e-08 32.6 0.1 2.2e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85125.1 - 2.2e-06 27.9 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAQ85125.1 - 2.7e-05 23.4 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EAQ85125.1 - 0.0005 19.2 0.0 0.001 18.2 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EAQ85125.1 - 0.00055 19.3 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EAQ85125.1 - 0.00083 18.1 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DHBP_synthase PF00926.14 EAQ85126.1 - 1.2e-73 246.4 0.0 5e-73 244.4 0.0 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Utp14 PF04615.8 EAQ85127.1 - 1.3e-184 615.4 50.2 1.3e-184 615.4 34.8 2.3 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EAQ85128.1 - 1.6e-17 63.1 0.4 2e-17 62.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF750 PF04721.12 EAQ85128.1 - 0.097 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF750) Abhydrolase_3 PF07859.8 EAQ85129.1 - 1.7e-39 135.5 0.1 5.9e-30 104.4 0.1 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EAQ85129.1 - 1.3e-12 47.0 0.0 5.4e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EAQ85129.1 - 8e-05 21.5 0.1 0.037 12.7 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EAQ85129.1 - 0.0044 16.7 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAQ85129.1 - 0.032 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SR-25 PF10500.4 EAQ85129.1 - 0.51 9.7 4.9 1.2 8.5 3.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CmcI PF04989.7 EAQ85129.1 - 0.95 8.7 2.3 19 4.5 0.0 2.5 3 0 0 3 3 3 0 Cephalosporin hydroxylase zf-RING_2 PF13639.1 EAQ85130.1 - 1.6e-09 37.4 6.7 2.5e-09 36.8 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAQ85130.1 - 4.2e-07 29.9 0.9 8e-07 29.0 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EAQ85130.1 - 4.2e-05 23.1 2.6 6.6e-05 22.4 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAQ85130.1 - 7.8e-05 22.4 1.2 0.00013 21.7 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAQ85130.1 - 0.0015 18.5 6.3 0.0026 17.7 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ85130.1 - 0.0079 15.8 3.6 0.014 15.0 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ85130.1 - 0.057 13.1 3.2 0.14 11.9 2.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain DUF1631 PF07793.6 EAQ85130.1 - 0.099 10.7 1.1 0.12 10.5 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Preseq_ALAS PF09029.5 EAQ85130.1 - 0.15 12.0 0.5 0.61 10.0 0.3 2.1 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence Tmpp129 PF10272.4 EAQ85130.1 - 0.31 9.7 2.1 0.83 8.3 1.3 1.8 1 1 0 1 1 1 0 Putative transmembrane protein precursor zf-Di19 PF05605.7 EAQ85130.1 - 0.49 10.5 4.3 14 5.9 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 EAQ85130.1 - 0.71 9.5 7.1 17 5.0 5.5 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_60s PF00428.14 EAQ85130.1 - 0.83 10.0 3.7 2 8.8 2.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Rtf2 PF04641.7 EAQ85130.1 - 1.9 7.5 4.7 3.7 6.6 1.5 2.3 2 1 0 2 2 2 0 Rtf2 RING-finger UPF0547 PF10571.4 EAQ85130.1 - 3.1 7.5 5.9 1.3 8.7 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pkinase PF00069.20 EAQ85131.1 - 9.5e-16 57.7 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85131.1 - 3.8e-06 26.1 0.0 5.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAP1 PF08601.5 EAQ85132.1 - 1.3e-38 133.6 13.2 1.3e-38 133.6 9.2 2.8 2 1 0 2 2 2 1 Transcription factor PAP1 CENP-H PF05837.7 EAQ85132.1 - 0.47 10.6 3.8 1.1 9.4 2.6 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) BSD PF03909.12 EAQ85133.1 - 2.3e-16 59.2 0.1 4.8e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.9 EAQ85133.1 - 0.065 12.8 0.2 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 Sigma-70 region 2 Mitofilin PF09731.4 EAQ85133.1 - 0.65 8.5 25.6 4.2 5.9 16.3 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein F-protein PF00469.15 EAQ85133.1 - 0.69 9.2 13.1 1.9 7.8 9.1 1.8 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef WGG PF10273.4 EAQ85134.1 - 7.6e-37 125.2 0.2 1.2e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EAQ85134.1 - 0.03 14.3 0.1 0.03 14.3 0.1 2.2 2 1 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) SDA1 PF05285.7 EAQ85134.1 - 1.5 8.0 16.4 0.23 10.6 8.5 1.6 2 0 0 2 2 2 0 SDA1 FAM176 PF14851.1 EAQ85134.1 - 3 7.5 6.7 1.9 8.1 1.9 2.0 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.5 EAQ85134.1 - 8.7 6.6 12.7 20 5.4 8.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Flavokinase PF01687.12 EAQ85135.1 - 3.6e-34 117.3 0.0 5.6e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase NAD_binding_10 PF13460.1 EAQ85135.1 - 9.2e-09 35.5 0.4 1.6e-08 34.7 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ85135.1 - 9.1e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EAQ85135.1 - 0.098 11.8 0.3 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family PAS PF00989.19 EAQ85136.1 - 0.00018 21.2 0.0 0.00046 19.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EAQ85136.1 - 0.002 18.0 9.4 0.0047 16.8 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EAQ85137.1 - 1.9e-34 118.9 27.1 7.3e-34 117.0 15.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAQ85137.1 - 2.9e-07 29.1 2.5 4.6e-07 28.4 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cellulase PF00150.13 EAQ85139.1 - 2.8e-10 39.8 0.0 4.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1510 PF07423.6 EAQ85139.1 - 0.41 9.9 2.6 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Synaptobrevin PF00957.16 EAQ85139.1 - 0.9 9.1 3.3 1.5 8.5 2.3 1.3 1 0 0 1 1 1 0 Synaptobrevin Transket_pyr PF02779.19 EAQ85140.1 - 1.5e-42 145.1 0.0 2.4e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EAQ85140.1 - 1.3e-32 112.3 0.1 2.4e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Cyt-b5 PF00173.23 EAQ85141.1 - 5e-24 83.9 0.2 6.4e-24 83.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 EAQ85141.1 - 0.047 13.6 1.1 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 YqzH-like protein Dermcidin PF15291.1 EAQ85142.1 - 0.042 14.0 0.5 0.042 14.0 0.3 2.4 3 0 0 3 3 3 0 Dermcidin, antibiotic peptide DSBA PF01323.15 EAQ85143.1 - 1.1e-16 61.0 0.0 1.3e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Ank_2 PF12796.2 EAQ85144.1 - 4.1e-30 103.9 0.6 5.4e-10 39.4 0.1 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ85144.1 - 2.9e-25 87.7 8.7 7.5e-06 26.0 0.4 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EAQ85144.1 - 1.7e-23 81.1 18.5 2.1e-09 36.7 0.2 6.6 5 1 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EAQ85144.1 - 7.9e-23 80.3 2.1 0.00037 20.9 0.0 5.3 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85144.1 - 9.7e-20 68.6 1.6 1.1e-06 28.2 0.0 6.6 6 1 0 6 6 6 3 Ankyrin repeat zf-C2H2 PF00096.21 EAQ85146.1 - 1.7e-22 78.3 24.6 6e-06 26.2 0.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ85146.1 - 1.8e-19 69.0 26.6 3e-07 30.3 0.7 4.7 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ85146.1 - 2.5e-15 55.5 24.2 0.00028 21.0 2.6 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ85146.1 - 1.4e-05 25.1 3.6 1.8 8.8 0.0 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAQ85146.1 - 0.00087 19.1 13.5 0.45 10.4 0.3 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EAQ85146.1 - 0.0059 16.7 9.9 4.8 7.5 0.4 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type ADK_lid PF05191.9 EAQ85146.1 - 0.076 12.6 5.0 4.3 7.0 0.2 3.6 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 EAQ85146.1 - 0.18 11.8 10.4 14 5.7 0.2 3.8 2 1 2 4 4 4 0 Zinc ribbon domain XPA_N PF01286.13 EAQ85146.1 - 0.19 11.4 0.2 0.19 11.4 0.1 3.3 4 0 0 4 4 4 0 XPA protein N-terminal DUF2072 PF09845.4 EAQ85146.1 - 0.23 11.3 1.0 0.49 10.3 0.7 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) C1_1 PF00130.17 EAQ85146.1 - 0.26 11.0 4.0 0.54 10.0 0.7 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Viral_NABP PF05515.6 EAQ85146.1 - 0.29 11.4 3.0 0.56 10.4 2.1 1.4 1 0 0 1 1 1 0 Viral nucleic acid binding zf-TRAF PF02176.13 EAQ85146.1 - 0.36 11.2 8.3 2 8.8 0.4 2.5 1 1 1 3 3 3 0 TRAF-type zinc finger LIM PF00412.17 EAQ85146.1 - 1.6 8.8 5.2 21 5.2 0.1 3.0 2 1 1 3 3 3 0 LIM domain zf-BED PF02892.10 EAQ85146.1 - 1.6 8.5 7.0 22 4.9 0.6 3.3 3 0 0 3 3 3 0 BED zinc finger DUF2256 PF10013.4 EAQ85146.1 - 2.7 7.8 5.2 14 5.5 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) HNH PF01844.18 EAQ85146.1 - 7.3 6.5 8.3 21 5.0 0.1 3.7 4 0 0 4 4 4 0 HNH endonuclease Na_Ca_ex PF01699.19 EAQ85147.1 - 2.9e-42 143.5 22.1 1.6e-23 82.8 7.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Patatin PF01734.17 EAQ85148.1 - 6.9e-40 137.1 0.0 1.2e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase HeLo PF14479.1 EAQ85149.1 - 6.1e-64 215.6 0.1 1e-63 214.9 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 EAQ85149.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain FAD_binding_4 PF01565.18 EAQ85150.1 - 3.9e-14 52.3 0.0 3.9e-14 52.3 0.0 2.0 2 1 1 3 3 3 1 FAD binding domain Abhydrolase_3 PF07859.8 EAQ85151.1 - 1.6e-34 119.3 1.2 7.3e-34 117.1 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAQ85151.1 - 0.00013 20.7 0.5 0.0017 17.0 0.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAQ85151.1 - 0.00021 21.0 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pex14_N PF04695.8 EAQ85152.1 - 1.6e-40 138.3 0.0 1.6e-40 138.3 0.0 2.7 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ERM PF00769.14 EAQ85152.1 - 4.3e-05 23.1 2.7 7.8e-05 22.3 1.9 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family zf-C4H2 PF10146.4 EAQ85152.1 - 0.00018 21.5 5.5 0.00018 21.5 3.8 2.1 2 1 0 2 2 2 1 Zinc finger-containing protein IncA PF04156.9 EAQ85152.1 - 0.00047 19.8 1.1 0.00071 19.2 0.8 1.2 1 0 0 1 1 1 1 IncA protein DUF1978 PF09321.5 EAQ85152.1 - 0.019 14.4 6.3 0.03 13.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DUF3584 PF12128.3 EAQ85152.1 - 0.035 11.4 9.9 0.045 11.0 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) tRNA-synt_His PF13393.1 EAQ85152.1 - 0.041 12.9 2.2 0.32 10.0 0.0 2.2 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF848 PF05852.6 EAQ85152.1 - 0.052 13.4 8.4 0.093 12.5 5.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) AAA_13 PF13166.1 EAQ85152.1 - 0.058 11.8 2.5 0.095 11.1 1.7 1.3 1 0 0 1 1 1 0 AAA domain HLH PF00010.21 EAQ85152.1 - 0.16 11.6 5.4 3.8 7.2 0.8 3.0 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain PilJ PF13675.1 EAQ85152.1 - 0.28 11.5 3.8 2.4 8.5 2.7 2.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-Q PF13094.1 EAQ85152.1 - 0.33 10.9 8.8 0.57 10.2 6.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IFT57 PF10498.4 EAQ85152.1 - 0.4 9.3 5.8 0.61 8.7 4.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.7 EAQ85152.1 - 0.66 9.7 9.2 2.9 7.6 0.5 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.7 EAQ85152.1 - 0.95 9.1 3.5 1.2 8.7 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Syntaxin PF00804.20 EAQ85152.1 - 2.3 8.4 10.1 28 4.9 7.0 2.2 1 1 0 1 1 1 0 Syntaxin ADIP PF11559.3 EAQ85152.1 - 3.1 7.6 11.2 8.8 6.2 7.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EAQ85152.1 - 6.4 5.6 10.3 9.7 5.0 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ndc80_HEC PF03801.8 EAQ85153.1 - 1.3e-63 213.2 0.4 2.3e-63 212.4 0.3 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family DUF1664 PF07889.7 EAQ85153.1 - 0.0019 17.9 0.3 0.0019 17.9 0.2 4.5 3 2 2 5 5 5 1 Protein of unknown function (DUF1664) WASH_WAHD PF11945.3 EAQ85153.1 - 0.0019 17.5 3.6 0.0019 17.5 2.5 1.7 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF4391 PF14335.1 EAQ85153.1 - 0.007 15.7 7.3 0.007 15.7 5.1 3.3 2 1 2 4 4 4 1 Domain of unknown function (DUF4391) 2OG-Fe_Oxy_2 PF10014.4 EAQ85153.1 - 0.015 14.7 0.1 0.19 11.0 0.0 2.5 3 0 0 3 3 3 0 2OG-Fe dioxygenase Tropomyosin_1 PF12718.2 EAQ85153.1 - 0.088 12.6 56.0 0.027 14.2 11.3 4.3 2 2 2 4 4 4 0 Tropomyosin like DUF3584 PF12128.3 EAQ85153.1 - 0.36 8.1 37.3 0.52 7.5 9.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SecIII_SopE_N PF05364.9 EAQ85153.1 - 0.49 10.2 3.0 40 4.1 0.0 4.0 5 0 0 5 5 5 0 Salmonella type III secretion SopE effector N-terminus V_ATPase_I PF01496.14 EAQ85153.1 - 1.2 6.8 27.9 0.71 7.6 4.9 2.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 EAQ85153.1 - 1.3 8.7 44.8 0.8 9.4 8.7 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 EAQ85153.1 - 1.5 8.2 48.0 1.9 7.8 14.4 3.1 2 1 0 2 2 2 0 Intermediate filament protein Prefoldin PF02996.12 EAQ85153.1 - 5.7 6.6 28.3 3.4 7.3 0.7 5.0 4 1 1 5 5 5 0 Prefoldin subunit OmpH PF03938.9 EAQ85153.1 - 6.1 6.7 37.7 5.5 6.9 10.1 3.1 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Cauli_AT PF03233.8 EAQ85153.1 - 7.9 6.1 14.1 0.27 10.9 1.4 3.2 2 1 1 3 3 3 0 Aphid transmission protein DUF4407 PF14362.1 EAQ85153.1 - 9.4 5.0 26.6 1.4 7.8 5.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Methyltransf_4 PF02390.12 EAQ85154.1 - 1.3e-51 174.4 0.0 1.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAQ85154.1 - 7.1e-05 23.3 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ85154.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EAQ85154.1 - 0.0062 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EAQ85154.1 - 0.0091 15.5 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ85154.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85154.1 - 0.028 14.8 0.0 0.24 11.9 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EAQ85154.1 - 0.032 13.5 0.0 0.046 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Homoserine_dh PF00742.14 EAQ85155.1 - 3.5e-52 176.6 0.0 4.7e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EAQ85155.1 - 4.1e-18 65.8 0.0 7.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EAQ85156.1 - 1.4e-28 98.8 14.8 1.4e-28 98.8 10.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) TBD PF12845.2 EAQ85156.1 - 0.0065 15.9 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 TBD domain Cupin_2 PF07883.6 EAQ85160.1 - 2.6e-13 49.2 0.1 3.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EAQ85160.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EAQ85160.1 - 6.3e-05 22.4 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EAQ85160.1 - 0.0034 17.0 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EAQ85160.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 EAQ85160.1 - 0.097 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Glyco_hydro_7 PF00840.15 EAQ85161.1 - 8.4e-108 360.5 16.1 9.8e-108 360.2 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.15 EAQ85162.1 - 1.5e-29 102.6 0.1 1.6e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 zf-Nse PF11789.3 EAQ85163.1 - 1.4e-20 72.5 0.7 2.6e-20 71.6 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EAQ85163.1 - 6.8e-05 22.5 0.6 0.00016 21.3 0.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EAQ85163.1 - 0.00011 21.6 0.4 0.0002 20.8 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 EAQ85163.1 - 0.0014 18.4 0.4 0.0024 17.6 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EAQ85163.1 - 0.0063 16.3 0.1 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EAQ85163.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 EAQ85163.1 - 0.041 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.2 EAQ85163.1 - 0.056 13.5 0.1 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger Clr5 PF14420.1 EAQ85164.1 - 2.2e-19 69.0 2.8 2.9e-19 68.6 2.0 1.2 1 0 0 1 1 1 1 Clr5 domain FYTT PF07078.6 EAQ85164.1 - 0.011 15.1 0.8 0.013 14.8 0.5 1.1 1 0 0 1 1 1 0 Forty-two-three protein MORN_2 PF07661.8 EAQ85165.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 MORN repeat variant EIID-AGA PF03613.9 EAQ85166.1 - 0.19 10.6 0.2 0.32 9.9 0.1 1.3 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component Arrestin_C PF02752.17 EAQ85167.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF605 PF04652.11 EAQ85167.1 - 6.7 5.9 8.9 8.8 5.6 6.2 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EAQ85168.1 - 1.5e-20 72.2 16.2 1.3e-06 28.0 0.6 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EAQ85168.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAQ85168.1 - 0.014 13.2 0.0 0.019 12.8 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Miro PF08477.8 EAQ85169.1 - 3.5e-35 121.0 0.0 6.9e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EAQ85169.1 - 1.9e-33 114.0 0.0 4.1e-33 112.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EAQ85169.1 - 5.1e-33 112.2 0.8 8.2e-33 111.5 0.2 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 EAQ85169.1 - 2.1e-25 88.9 0.0 7.1e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EAQ85169.1 - 2.1e-08 34.1 0.0 6.9e-05 22.7 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EAQ85169.1 - 2.1e-07 31.1 0.0 0.005 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain EF-hand_7 PF13499.1 EAQ85169.1 - 3.1e-07 30.4 0.1 0.0023 18.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.1 EAQ85169.1 - 8.1e-07 29.1 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_1 PF00036.27 EAQ85169.1 - 1e-06 27.5 2.8 0.013 14.7 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.1 EAQ85169.1 - 1.4e-06 27.7 0.0 0.0018 17.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EAQ85169.1 - 4.4e-06 26.6 0.1 0.054 13.3 0.1 2.9 2 1 1 3 3 3 2 Dynamin family EF-hand_6 PF13405.1 EAQ85169.1 - 3.9e-05 23.1 3.1 0.04 13.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain GTP_EFTU PF00009.22 EAQ85169.1 - 0.00031 20.2 0.0 2.1 7.7 0.0 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EAQ85169.1 - 0.00044 20.5 0.0 0.94 9.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter EF-hand_5 PF13202.1 EAQ85169.1 - 0.00046 19.4 4.4 0.41 10.0 1.0 2.7 2 0 0 2 2 2 2 EF hand MobB PF03205.9 EAQ85169.1 - 0.00047 19.8 0.0 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EAQ85169.1 - 0.00049 19.3 0.0 0.73 9.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF815 PF05673.8 EAQ85169.1 - 0.00073 18.5 0.0 0.54 9.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 EAQ85169.1 - 0.00091 18.9 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.1 EAQ85169.1 - 0.0018 17.9 0.0 0.048 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EAQ85169.1 - 0.0026 17.9 0.0 0.6 10.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EAQ85169.1 - 0.0033 16.8 0.1 2.1 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAQ85169.1 - 0.0049 16.7 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAQ85169.1 - 0.012 15.5 0.0 3.9 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EAQ85169.1 - 0.016 14.4 0.0 0.73 9.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EAQ85169.1 - 0.019 14.6 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EAQ85169.1 - 0.024 14.9 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EAQ85169.1 - 0.041 13.3 1.7 6.2 6.2 0.0 3.8 2 2 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EAQ85169.1 - 0.05 12.6 0.0 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Septin EF-hand_10 PF14788.1 EAQ85169.1 - 0.055 13.1 0.6 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 EF hand AAA PF00004.24 EAQ85169.1 - 0.055 13.6 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.8 EAQ85169.1 - 0.065 12.0 0.1 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.13 EAQ85169.1 - 0.08 12.4 0.1 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 EAQ85169.1 - 0.098 12.1 0.1 17 4.8 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SPARC_Ca_bdg PF10591.4 EAQ85169.1 - 0.1 12.5 0.0 10 6.1 0.0 3.0 3 1 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region AIG1 PF04548.11 EAQ85169.1 - 0.1 11.6 0.9 0.87 8.6 0.2 2.5 3 0 0 3 3 3 0 AIG1 family AAA_17 PF13207.1 EAQ85169.1 - 0.14 13.0 0.0 24 5.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.1 EAQ85169.1 - 0.76 9.4 2.9 11 5.7 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair Pox_MCEL PF03291.11 EAQ85170.1 - 9e-67 225.2 0.0 4.1e-48 163.9 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EAQ85170.1 - 1.5e-09 38.2 0.1 0.0032 17.8 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85170.1 - 1.5e-08 35.1 0.0 3.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85170.1 - 3.7e-07 30.5 0.1 1.4e-05 25.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85170.1 - 6.8e-07 29.5 0.0 2e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ85170.1 - 4.1e-06 26.4 0.0 3.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ85170.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EAQ85170.1 - 0.00016 20.7 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.1 EAQ85170.1 - 0.00088 17.9 0.2 0.00088 17.9 0.2 1.6 2 0 0 2 2 2 1 Raftlin Methyltransf_9 PF08003.6 EAQ85170.1 - 0.04 12.6 0.0 0.064 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EAQ85170.1 - 0.1 12.5 0.2 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SpoIIIAH PF12685.2 EAQ85170.1 - 7.2 6.0 7.7 18 4.7 0.0 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein RPN7 PF10602.4 EAQ85171.1 - 3.3e-57 192.7 1.4 3.3e-57 192.6 0.3 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EAQ85171.1 - 4.5e-13 49.4 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.16 EAQ85172.1 - 1.6e-36 126.0 0.0 2.1e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Ribosomal_L33 PF00471.15 EAQ85173.1 - 0.057 13.6 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L33 AAA_13 PF13166.1 EAQ85174.1 - 0.00047 18.7 16.7 0.00047 18.7 11.6 3.3 1 1 2 3 3 3 1 AAA domain Sec8_exocyst PF04048.9 EAQ85174.1 - 0.0074 15.9 4.5 0.0074 15.9 3.1 4.4 3 2 1 4 4 4 1 Sec8 exocyst complex component specific domain Reo_sigmaC PF04582.7 EAQ85174.1 - 0.11 11.6 29.9 1.3 8.1 3.6 5.3 1 1 4 5 5 5 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EAQ85174.1 - 0.42 10.4 83.8 0.0095 15.7 20.8 5.5 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) CD99L2 PF12301.3 EAQ85175.1 - 0.00066 19.4 0.4 0.0015 18.2 0.0 1.7 1 1 1 2 2 2 1 CD99 antigen like protein 2 PHO4 PF01384.15 EAQ85175.1 - 0.0085 14.7 0.0 0.0085 14.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Sex_peptide PF08138.6 EAQ85175.1 - 0.062 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family DUF3302 PF11742.3 EAQ85175.1 - 0.1 12.4 0.6 0.14 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) NUC153 PF08159.7 EAQ85176.1 - 4.3e-13 48.6 1.3 4.3e-13 48.6 0.9 1.9 2 0 0 2 2 2 1 NUC153 domain WD40 PF00400.27 EAQ85176.1 - 6.7e-05 22.6 0.0 0.036 13.9 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Med13_C PF06333.7 EAQ85177.1 - 1.4e-119 399.4 0.0 2.2e-119 398.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EAQ85177.1 - 1.3e-65 221.6 0.0 1.6e-37 129.1 0.0 2.4 1 1 1 2 2 2 2 Mediator complex subunit 13 N-terminal PNP_UDP_1 PF01048.15 EAQ85178.1 - 1.3e-39 135.6 0.8 1.5e-39 135.3 0.6 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Atx10homo_assoc PF09759.4 EAQ85179.1 - 9.1e-11 41.4 0.0 2.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.24 EAQ85180.1 - 7.2e-95 310.6 36.8 8.6e-14 50.9 0.6 12.8 12 1 0 12 12 12 10 KH domain KH_3 PF13014.1 EAQ85180.1 - 1.6e-66 219.0 29.8 3e-11 42.6 0.2 12.0 12 0 0 12 12 12 9 KH domain SLS PF14611.1 EAQ85180.1 - 3.3e-17 62.6 7.3 0.00084 18.8 0.1 9.0 4 3 7 11 11 11 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EAQ85180.1 - 4.6e-13 48.5 24.2 0.013 15.0 0.2 8.6 8 1 0 9 9 9 5 KH domain KH_5 PF13184.1 EAQ85180.1 - 0.0018 18.0 9.1 2.1 8.1 0.1 6.3 5 1 1 6 6 6 1 NusA-like KH domain KH_4 PF13083.1 EAQ85180.1 - 0.012 15.2 5.8 0.93 9.1 0.0 5.4 5 0 0 5 5 5 0 KH domain BMC PF00936.14 EAQ85180.1 - 0.017 14.7 0.0 0.97 9.1 0.0 3.2 3 0 0 3 3 3 0 BMC domain Pkinase PF00069.20 EAQ85181.1 - 1.2e-11 44.3 0.0 1.2e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85181.1 - 6.5e-07 28.6 0.0 6.9e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short PF00106.20 EAQ85182.1 - 2.2e-29 102.5 0.7 3.1e-29 102.0 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ85182.1 - 7e-27 94.7 0.1 1.1e-26 94.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ85182.1 - 1.9e-10 40.7 0.2 3.2e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ85182.1 - 6.3e-06 25.7 0.1 2.1e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EAQ85182.1 - 0.0041 16.7 0.1 0.011 15.4 0.1 1.8 1 0 0 1 1 1 1 PA domain 3Beta_HSD PF01073.14 EAQ85182.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EAQ85182.1 - 0.041 12.7 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ARID PF01388.16 EAQ85183.1 - 2.8e-20 71.9 0.0 6.8e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SEN1_N PF12726.2 EAQ85183.1 - 0.2 9.6 0.1 0.31 9.0 0.0 1.2 1 0 0 1 1 1 0 SEN1 N terminal SelR PF01641.13 EAQ85185.1 - 1.8e-38 130.9 0.0 2.3e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EAQ85185.1 - 0.0022 17.7 0.1 0.42 10.3 0.0 2.2 2 0 0 2 2 2 2 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 EAQ85185.1 - 0.0043 16.8 0.5 0.5 10.2 0.1 2.2 2 0 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EAQ85185.1 - 0.029 13.6 1.1 1.7 8.0 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Mss51 PF13824.1 EAQ85185.1 - 0.19 11.6 2.5 8.1 6.3 0.3 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L37e PF01907.14 EAQ85185.1 - 0.31 10.8 5.5 0.65 9.8 1.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e ArfGap PF01412.13 EAQ85186.1 - 1.7e-10 40.6 5.3 7.1e-08 32.2 0.7 2.3 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf DUF500 PF04366.7 EAQ85188.1 - 6.9e-43 145.0 0.1 1.2e-42 144.3 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EAQ85188.1 - 5.8e-14 51.2 0.2 1.5e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EAQ85188.1 - 4.6e-13 48.4 0.0 1.1e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAQ85188.1 - 9.5e-13 47.5 1.8 9.5e-13 47.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain HSP70 PF00012.15 EAQ85192.1 - 2.1e-269 894.5 13.9 2.4e-269 894.3 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ85192.1 - 8.5e-18 64.0 2.0 2.4e-16 59.2 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EAQ85192.1 - 0.01 14.9 5.5 0.011 14.8 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HEPPP_synt_1 PF07307.6 EAQ85192.1 - 0.081 12.3 0.5 0.2 11.0 0.3 1.6 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 FtsA PF14450.1 EAQ85192.1 - 0.52 10.1 9.9 4.4 7.1 0.1 3.8 3 1 0 3 3 3 0 Cell division protein FtsA SpoIIAA-like PF11964.3 EAQ85192.1 - 0.82 9.9 3.8 9.1 6.6 0.1 3.1 3 0 0 3 3 3 0 SpoIIAA-like GTP_EFTU PF00009.22 EAQ85193.1 - 1.1e-46 158.6 0.0 2e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EAQ85193.1 - 8.9e-23 80.2 0.9 1.8e-22 79.2 0.6 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EAQ85193.1 - 2.7e-07 30.6 0.0 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAQ85193.1 - 1e-06 28.7 0.0 2.7e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAQ85193.1 - 7.2e-06 25.9 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EAQ85193.1 - 4.2e-05 23.1 0.0 8.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 EAQ85193.1 - 0.0017 17.5 0.1 0.2 10.8 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EAQ85193.1 - 0.013 15.9 0.0 0.039 14.4 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein Cpn60_TCP1 PF00118.19 EAQ85194.1 - 9.1e-146 486.2 5.4 1e-145 486.0 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HECT PF00632.20 EAQ85195.1 - 1.3e-68 231.4 0.0 2e-68 230.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) YhjQ PF06564.7 EAQ85195.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein zf-C2H2_2 PF12756.2 EAQ85196.1 - 9.6e-34 115.5 9.4 1e-27 96.1 1.4 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EAQ85196.1 - 1.9e-09 37.3 14.2 6.4e-06 26.1 2.2 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ85196.1 - 8.2e-08 32.1 6.3 7.5e-07 29.1 1.1 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EAQ85196.1 - 0.00079 19.6 18.5 0.21 11.9 0.3 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-DBF PF07535.7 EAQ85196.1 - 0.021 14.4 0.2 0.021 14.4 0.2 2.9 3 0 0 3 3 3 0 DBF zinc finger SnoaL_2 PF12680.2 EAQ85196.1 - 0.028 14.8 0.1 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 SnoaL-like domain zf-C2H2_6 PF13912.1 EAQ85196.1 - 0.3 11.0 0.1 0.3 11.0 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger VHS PF00790.14 EAQ85197.1 - 5.5e-22 77.9 0.0 1.3e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EAQ85197.1 - 4.5e-07 29.7 0.8 9.7e-07 28.6 0.5 1.5 1 0 0 1 1 1 1 GAT domain RWD PF05773.17 EAQ85198.1 - 5.5e-05 23.0 0.3 0.0026 17.6 0.0 2.5 2 0 0 2 2 2 1 RWD domain Mu-like_Com PF10122.4 EAQ85198.1 - 0.00081 18.3 0.4 0.0022 17.0 0.3 1.7 1 0 0 1 1 1 1 Mu-like prophage protein Com FYVE PF01363.16 EAQ85198.1 - 0.61 10.0 7.6 5.1 7.0 5.2 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-CHY PF05495.7 EAQ85198.1 - 1.6 8.9 4.6 7 6.8 0.3 2.3 2 0 0 2 2 2 0 CHY zinc finger OrfB_Zn_ribbon PF07282.6 EAQ85198.1 - 2.1 8.0 6.7 0.24 11.1 0.2 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain BING4CT PF08149.6 EAQ85200.1 - 0.00076 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 BING4CT (NUC141) domain DUF3295 PF11702.3 EAQ85202.1 - 2.7e-146 488.5 35.6 3.7e-82 276.9 15.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EAQ85202.1 - 6.7e-13 47.9 2.2 1.1e-12 47.2 1.5 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans_2 PF11951.3 EAQ85204.1 - 0.014 13.9 0.1 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPMT PF05724.6 EAQ85204.1 - 0.018 14.4 0.0 0.076 12.4 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) AMP-binding PF00501.23 EAQ85205.1 - 8.4e-77 258.3 0.1 1.1e-76 257.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UCH PF00443.24 EAQ85206.1 - 1.3e-40 139.2 0.0 1.9e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ85206.1 - 5.8e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EAQ85206.1 - 0.00015 22.0 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 EAQ85206.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain VHS PF00790.14 EAQ85207.1 - 2.6e-39 134.0 0.0 6e-38 129.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain UIM PF02809.15 EAQ85207.1 - 1.3e-05 24.3 10.6 0.0082 15.6 0.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif His_Phos_1 PF00300.17 EAQ85208.1 - 6.9e-12 45.7 0.0 1.5e-11 44.6 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF3753 PF12575.3 EAQ85209.1 - 0.029 14.1 0.8 0.077 12.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DctQ PF04290.7 EAQ85209.1 - 0.15 11.7 6.9 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Helitron_like_N PF14214.1 EAQ85210.1 - 3.3e-22 79.1 0.1 5.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 EAQ85210.1 - 0.00098 17.0 0.0 0.0014 16.4 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EAQ85210.1 - 0.0016 17.5 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ85210.1 - 0.0018 18.3 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF164 PF02591.10 EAQ85210.1 - 6.6 6.6 7.8 2 8.3 0.1 3.1 4 0 0 4 4 4 0 Putative zinc ribbon domain PIF1 PF05970.9 EAQ85211.1 - 7.8e-19 67.8 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ85211.1 - 6.8e-06 25.8 0.1 1.8e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ85211.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EAQ85212.1 - 4.3e-16 58.8 0.0 7.5e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ85212.1 - 0.00041 20.4 0.0 0.0026 17.8 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EAQ85212.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank PF00023.25 EAQ85213.1 - 2.7e-65 213.0 17.3 1.4e-09 37.2 0.1 8.3 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 EAQ85213.1 - 1.6e-63 211.0 10.5 9e-23 80.4 0.2 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ85213.1 - 1.8e-52 174.8 19.1 7.5e-12 45.4 0.2 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ85213.1 - 2.5e-37 126.0 8.9 4e-10 39.5 0.1 5.2 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85213.1 - 2.5e-36 120.0 7.1 6e-05 22.9 0.0 8.0 7 0 0 7 7 7 7 Ankyrin repeat PNP_UDP_1 PF01048.15 EAQ85213.1 - 3.8e-16 58.7 1.5 5.1e-09 35.4 0.0 3.8 3 1 0 4 4 4 2 Phosphorylase superfamily NACHT PF05729.7 EAQ85213.1 - 1.3e-05 24.9 0.0 3.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF1662 PF07878.6 EAQ85213.1 - 0.0019 17.8 0.1 97 2.8 0.0 5.4 6 0 0 6 6 6 0 Protein of unknown function (DUF1662) Nse4-Nse3_bdg PF15412.1 EAQ85213.1 - 0.01 15.6 0.5 7.3 6.5 0.0 4.4 5 0 0 5 5 5 0 Binding domain of Nse4/EID3 to Nse3-MAGE AAA_22 PF13401.1 EAQ85213.1 - 0.02 15.0 0.0 0.087 12.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EAQ85213.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 EAQ85213.1 - 0.16 11.0 0.4 11 5.0 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EAQ85213.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EAQ85213.1 - 1.4 7.8 2.9 8.6 5.2 0.2 2.1 1 1 0 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 EAQ85214.1 - 1.8e-46 157.8 0.1 2.7e-25 89.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EAQ85214.1 - 5.8e-24 84.7 47.4 2.2e-17 63.1 13.4 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EAQ85214.1 - 1e-22 81.4 0.3 1.1e-07 32.1 0.3 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EAQ85214.1 - 6.8e-10 38.3 3.4 0.00094 18.6 0.5 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 EAQ85214.1 - 3.8e-07 29.5 3.1 0.13 11.4 0.0 3.9 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAQ85214.1 - 0.0003 21.1 6.6 0.06 13.6 0.4 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAQ85214.1 - 0.00058 19.0 0.5 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ85214.1 - 0.00086 19.3 2.0 0.68 9.8 0.2 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EAQ85214.1 - 0.011 15.1 0.7 5.4 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAQ85214.1 - 0.012 15.1 2.4 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAQ85214.1 - 0.015 15.1 0.2 22 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EAQ85214.1 - 0.025 14.7 0.2 4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 EAQ85214.1 - 0.079 12.3 0.4 2.3 7.5 0.0 2.6 3 0 0 3 3 3 0 MutS domain V SRP54 PF00448.17 EAQ85214.1 - 0.13 11.7 2.4 10 5.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.1 EAQ85214.1 - 0.15 11.0 0.0 6.6 5.6 0.1 2.7 3 0 0 3 3 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAQ85214.1 - 0.21 11.0 0.4 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EAQ85214.1 - 0.21 10.9 1.0 10 5.4 0.2 2.4 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 EAQ85214.1 - 0.37 9.4 0.1 1.8 7.1 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 EAQ85214.1 - 1.4 8.9 3.0 43 4.0 0.9 2.7 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.1 EAQ85214.1 - 1.5 7.1 0.1 20 3.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAQ85214.1 - 1.6 8.5 4.1 15 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 tRNA-synt_2 PF00152.15 EAQ85215.1 - 2.7e-85 286.1 0.4 3.6e-85 285.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAQ85215.1 - 2.9e-12 46.2 0.1 7.5e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAQ85215.1 - 1.9e-08 33.7 0.0 0.00035 19.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Di19 PF05605.7 EAQ85216.1 - 0.012 15.6 0.1 0.04 14.0 0.1 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding HALZ PF02183.13 EAQ85216.1 - 0.11 12.1 4.8 0.092 12.4 1.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-C2H2 PF00096.21 EAQ85216.1 - 1.9 8.9 3.8 0.69 10.3 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nop14 PF04147.7 EAQ85217.1 - 1.3 6.8 9.0 1.5 6.6 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family AT_hook PF02178.14 EAQ85217.1 - 2.6 8.0 6.3 0.26 11.0 0.3 2.6 3 0 0 3 3 3 0 AT hook motif Pyridox_oxidase PF01243.15 EAQ85218.1 - 1.7e-05 24.7 0.0 0.038 14.0 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase CTP_transf_2 PF01467.21 EAQ85219.1 - 9.3e-16 58.2 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Ion_trans_2 PF07885.11 EAQ85221.1 - 1.1e-33 114.7 28.1 5.2e-21 74.1 2.3 3.5 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.26 EAQ85221.1 - 7.7 5.7 23.9 0.076 12.2 1.3 3.4 2 1 1 3 3 3 0 Ion transport protein Ribosomal_L6 PF00347.18 EAQ85223.1 - 6.1e-18 65.0 0.0 4.7e-12 46.2 0.0 3.1 3 1 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EAQ85224.1 - 1.4e-49 168.8 0.7 2.5e-49 168.0 0.5 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family PALP PF00291.20 EAQ85225.1 - 0.0026 17.0 0.1 1 8.4 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme RVT_1 PF00078.22 EAQ85226.1 - 1.4e-22 80.1 0.0 3.2e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.9 EAQ85226.1 - 7.4e-07 28.6 0.1 1.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SlyX PF04102.7 EAQ85226.1 - 0.008 16.5 4.1 0.23 11.8 0.6 2.9 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ85226.1 - 0.073 12.0 1.9 0.14 11.1 1.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ85226.1 - 0.52 10.3 5.9 0.13 12.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) HET PF06985.6 EAQ85227.1 - 3.2e-30 105.0 0.0 7.7e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) XRCC4 PF06632.7 EAQ85227.1 - 0.14 11.0 1.6 0.21 10.4 1.1 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Lactonase PF10282.4 EAQ85228.1 - 3.7e-14 52.5 0.0 3.4e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 EAQ85229.1 - 3.1e-45 153.6 0.0 4.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 EAQ85229.1 - 0.024 14.6 0.0 0.089 12.8 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Complex1_30kDa PF00329.14 EAQ85230.1 - 2.2e-34 117.8 0.1 3.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 EAQ85231.1 - 3.9e-19 67.9 11.8 7.6e-19 67.0 8.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EAQ85231.1 - 4.5e-09 35.8 0.0 1.4e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.26 EAQ85231.1 - 1e-07 31.6 0.6 4e-07 29.7 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ85231.1 - 7.1e-07 28.8 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_6 PF14259.1 EAQ85231.1 - 3.4e-05 23.7 0.0 0.00014 21.8 0.0 2.2 2 0 0 2 2 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EAQ85231.1 - 0.00013 21.5 10.2 0.00013 21.5 7.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EAQ85231.1 - 0.00018 20.7 2.7 0.00018 20.7 1.9 4.1 5 0 0 5 5 4 1 Rtf2 RING-finger ResIII PF04851.10 EAQ85231.1 - 0.00023 21.0 0.2 0.002 17.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RRM_5 PF13893.1 EAQ85231.1 - 0.00027 20.7 0.0 0.0006 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 EAQ85231.1 - 0.037 13.3 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Zip PF02535.17 EAQ85231.1 - 0.1 11.6 10.5 0.11 11.5 5.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Nup35_RRM_2 PF14605.1 EAQ85231.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.6 EAQ85231.1 - 0.39 10.4 7.0 0.77 9.4 4.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TTSSLRR PF12468.3 EAQ85233.1 - 0.14 11.7 1.5 0.73 9.4 0.1 2.4 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Ank PF00023.25 EAQ85234.1 - 3.3e-23 80.2 0.1 3.7e-07 29.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EAQ85234.1 - 1.4e-19 70.2 0.0 4.9e-19 68.4 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ85234.1 - 1.2e-17 63.8 0.1 1.3e-11 44.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85234.1 - 3.9e-13 48.2 0.1 0.0029 17.6 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EAQ85234.1 - 1.6e-11 44.0 0.3 0.00083 19.5 0.0 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FTCD_C PF04961.7 EAQ85234.1 - 0.11 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase FAD_binding_4 PF01565.18 EAQ85235.1 - 4.1e-20 71.6 1.6 3.1e-19 68.8 1.1 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ85235.1 - 2.3e-07 30.5 0.0 5.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 EAQ85236.1 - 3.4e-28 98.6 0.7 4.9e-28 98.1 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ85236.1 - 4.1e-28 98.7 0.0 5.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ85236.1 - 6.6e-09 35.6 0.2 1e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ85236.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAQ85236.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RVT_1 PF00078.22 EAQ85238.1 - 2.3e-21 76.1 0.0 3.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC PF07967.8 EAQ85239.1 - 2.8e-33 114.5 0.1 4.2e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 C3HC zinc finger-like BIR PF00653.16 EAQ85239.1 - 0.0038 17.5 0.1 0.0074 16.6 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain E1-E2_ATPase PF00122.15 EAQ85240.1 - 3.5e-50 170.1 1.3 3.9e-50 170.0 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ85240.1 - 6e-41 141.2 0.8 2e-40 139.5 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EAQ85240.1 - 1.9e-34 117.5 0.2 2.1e-10 40.5 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EAQ85240.1 - 1.7e-18 67.4 0.0 4.5e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ85240.1 - 5e-06 26.2 0.6 0.00063 19.3 0.3 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ85240.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FAD_binding_1 PF00667.15 EAQ85241.1 - 1.6e-39 135.6 0.0 3.2e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EAQ85241.1 - 1.1e-11 45.2 0.0 3.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EAQ85241.1 - 5.5e-09 36.1 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EAQ85241.1 - 0.017 15.0 1.5 0.033 14.1 0.1 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain Fe-ADH PF00465.14 EAQ85242.1 - 8.2e-102 340.5 0.0 1e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EAQ85242.1 - 3.3e-13 49.5 0.0 1.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EAQ85242.1 - 0.001 18.4 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Sec3_C PF09763.4 EAQ85244.1 - 6.6e-257 854.1 0.0 8.7e-257 853.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EAQ85244.1 - 8e-30 102.5 0.0 1.5e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EAQ85244.1 - 0.0031 17.5 0.7 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 Sec3 exocyst complex subunit EST1_DNA_bind PF10373.4 EAQ85244.1 - 0.13 11.4 0.8 0.22 10.7 0.1 1.7 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain DUF2018 PF09442.5 EAQ85244.1 - 0.23 12.0 1.7 0.52 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Vps52 PF04129.7 EAQ85244.1 - 0.54 8.7 4.6 0.3 9.5 0.2 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family HECT PF00632.20 EAQ85246.1 - 2.7e-82 276.4 0.0 9.4e-82 274.6 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) RRN3 PF05327.6 EAQ85246.1 - 0.0002 19.6 11.8 0.0002 19.6 8.2 1.8 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 HEAT PF02985.17 EAQ85246.1 - 0.27 11.4 1.8 20 5.6 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat E1_dh PF00676.15 EAQ85247.1 - 3.6e-86 288.6 0.0 4.2e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EAQ85247.1 - 0.00032 20.3 0.0 0.0051 16.3 0.0 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EAQ85247.1 - 0.041 12.7 0.0 0.51 9.2 0.0 2.3 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase McyA_C PF12593.3 EAQ85247.1 - 0.083 12.6 0.7 0.33 10.7 0.1 2.3 4 0 0 4 4 4 0 Microcystin synthetase C terminal XFP_N PF09364.5 EAQ85247.1 - 0.14 10.7 0.0 0.3 9.6 0.0 1.5 1 0 0 1 1 1 0 XFP N-terminal domain Ubie_methyltran PF01209.13 EAQ85248.1 - 2e-70 236.5 0.0 2.4e-42 144.6 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EAQ85248.1 - 1.4e-11 44.2 0.0 5.9e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ85248.1 - 1.5e-09 38.2 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85248.1 - 3.9e-09 36.8 0.0 1.1e-05 25.7 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85248.1 - 4.8e-08 33.2 0.0 2.4e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ85248.1 - 9.7e-08 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85248.1 - 3.1e-06 27.7 0.0 8.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ85248.1 - 4e-05 23.6 0.3 0.0002 21.3 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAQ85248.1 - 0.048 13.3 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EAQ85248.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF2433 PF10360.4 EAQ85249.1 - 1.9e-53 180.3 0.0 2.9e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 EAQ85249.1 - 0.0042 17.3 5.9 0.016 15.4 4.1 1.9 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 EAQ85249.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ85249.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Glyoxalase_2 PF12681.2 EAQ85250.1 - 8.3e-17 61.7 0.1 1.1e-16 61.4 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EAQ85250.1 - 1.1e-10 41.6 0.3 2.1e-10 40.6 0.2 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SBP_bac_11 PF13531.1 EAQ85251.1 - 0.029 13.9 0.2 0.5 9.9 0.1 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein Glyco_hydro_61 PF03443.9 EAQ85252.1 - 2.7e-15 56.8 0.0 1.8e-11 44.2 0.1 2.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 61 UFC1 PF08694.6 EAQ85252.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Fungal_trans_2 PF11951.3 EAQ85253.1 - 1.3e-10 40.4 0.0 1.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ85253.1 - 0.014 15.2 8.6 0.026 14.4 6.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EAQ85254.1 - 6.4e-07 29.0 2.6 9.8e-07 28.4 1.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Polysacc_synt_C PF14667.1 EAQ85254.1 - 0.91 9.3 16.1 2.6 7.8 0.7 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.1 EAQ85254.1 - 1.9 7.8 12.8 0.22 10.9 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Zds_C PF08632.5 EAQ85257.1 - 5.7e-31 105.6 0.5 9.5e-31 104.9 0.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Amidase PF01425.16 EAQ85258.1 - 4.1e-80 269.7 0.0 5.4e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Smr PF01713.16 EAQ85259.1 - 3.1e-13 49.6 0.1 3.7e-12 46.2 0.1 2.3 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 EAQ85259.1 - 2.4e-05 23.7 0.0 5.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 CUE domain Patched PF02460.13 EAQ85260.1 - 4e-72 243.3 18.2 4e-72 243.3 12.6 2.5 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 EAQ85260.1 - 1.1e-48 164.5 8.9 1.1e-48 164.5 6.1 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EAQ85260.1 - 3.2e-05 22.8 35.0 0.0074 15.0 7.4 2.6 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.14 EAQ85260.1 - 0.54 7.5 21.2 0.014 12.8 8.9 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family p450 PF00067.17 EAQ85262.1 - 4.1e-44 150.8 0.0 6.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4095 PF13338.1 EAQ85262.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) RNA_capsid PF03035.9 EAQ85263.1 - 0.051 13.3 0.6 0.06 13.1 0.4 1.1 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Pec_lyase_C PF00544.14 EAQ85263.1 - 0.1 12.0 0.4 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Pectate lyase Mt_ATP-synt_B PF05405.9 EAQ85263.1 - 0.14 11.5 2.8 0.17 11.3 1.9 1.0 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SART-1 PF03343.8 EAQ85263.1 - 0.33 9.2 12.0 0.38 9.0 8.3 1.0 1 0 0 1 1 1 0 SART-1 family SpoIIIAH PF12685.2 EAQ85263.1 - 0.4 10.1 5.2 0.47 9.9 3.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein NPR3 PF03666.8 EAQ85263.1 - 2.5 6.5 6.4 2.7 6.4 4.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rtf2 PF04641.7 EAQ85263.1 - 5.3 6.1 9.6 6 5.9 6.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FAM176 PF14851.1 EAQ85263.1 - 9.1 5.9 7.0 10 5.7 4.5 1.4 1 1 0 1 1 1 0 FAM176 family Lipase_GDSL_2 PF13472.1 EAQ85265.1 - 8e-14 52.1 0.2 1.2e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ85265.1 - 2.2e-13 50.6 0.6 1.8e-12 47.6 0.4 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 EAQ85265.1 - 1e-09 37.8 10.8 3.3e-09 36.2 7.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_3 PF14606.1 EAQ85265.1 - 0.093 12.4 0.1 0.22 11.2 0.1 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 EAQ85267.1 - 3.2e-08 33.0 0.0 0.00059 19.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain CN_hydrolase PF00795.17 EAQ85267.1 - 0.00066 19.0 0.1 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aha1_N PF09229.6 EAQ85268.1 - 4.1e-28 97.8 0.1 6.9e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EAQ85268.1 - 1.6e-19 70.2 1.1 2e-19 69.8 0.3 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EAQ85268.1 - 0.005 17.0 0.4 0.01 16.0 0.2 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Complex1_LYR_2 PF13233.1 EAQ85270.1 - 1.1e-21 77.2 0.0 3.2e-21 75.7 0.0 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EAQ85270.1 - 3e-05 23.7 0.3 4.7e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ85270.1 - 0.021 15.0 0.3 0.036 14.2 0.2 1.5 1 0 0 1 1 1 0 Complex1_LYR-like MMR_HSR1 PF01926.18 EAQ85271.1 - 5.5e-17 61.7 0.0 9.2e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAQ85271.1 - 4.1e-09 36.1 0.0 8.7e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EAQ85271.1 - 7.2e-07 28.6 0.0 0.00075 18.8 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ85271.1 - 2.5e-05 24.1 0.0 8.3e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Dynamin family IIGP PF05049.8 EAQ85271.1 - 0.00015 20.6 0.0 0.065 12.0 0.0 2.0 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EAQ85271.1 - 0.00059 19.0 0.0 0.00095 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EAQ85271.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 EAQ85271.1 - 0.0077 15.2 0.0 0.035 13.1 0.0 2.0 2 1 0 2 2 2 1 Septin ABC_tran PF00005.22 EAQ85271.1 - 0.0082 16.4 0.1 0.041 14.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EAQ85271.1 - 0.011 15.8 0.6 0.075 13.1 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ85271.1 - 0.014 15.3 1.5 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EAQ85271.1 - 0.023 14.6 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ85271.1 - 0.038 13.9 1.6 0.15 11.9 1.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 EAQ85271.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 EAQ85271.1 - 0.097 13.4 0.4 0.19 12.5 0.3 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EAQ85271.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-DHHC PF01529.15 EAQ85272.1 - 1.9e-25 89.2 6.8 1.9e-25 89.2 4.7 1.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Myb_DNA-bind_2 PF08914.6 EAQ85273.1 - 6.2e-09 35.5 1.1 2.6e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Nop25 PF09805.4 EAQ85273.1 - 0.71 9.9 9.1 0.067 13.2 2.7 1.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Peptidase_S64 PF08192.6 EAQ85274.1 - 0.099 10.9 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 EAQ85275.1 - 0.34 10.2 1.9 0.47 9.8 1.4 1.1 1 0 0 1 1 1 0 Vta1 like 2OG-FeII_Oxy_2 PF13532.1 EAQ85276.1 - 2.4e-25 89.5 0.0 3.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EAQ85276.1 - 0.013 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EAQ85277.1 - 3.6e-71 239.3 0.0 4.5e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85277.1 - 7.1e-30 103.9 0.0 8.9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85277.1 - 0.002 17.1 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ85277.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAQ85277.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EAQ85277.1 - 0.12 11.4 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EAQ85277.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cyclin_N PF00134.18 EAQ85279.1 - 1.5e-12 47.1 0.1 2.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAQ85279.1 - 6.2e-11 42.9 0.3 1.5e-10 41.7 0.2 1.7 1 1 0 1 1 1 1 Cyclin Glycos_transf_2 PF00535.21 EAQ85279.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 adh_short PF00106.20 EAQ85280.1 - 2.6e-14 53.4 0.1 6.1e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ85280.1 - 4e-07 29.8 0.2 8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.13 EAQ85281.1 - 1.2e-08 34.7 6.2 2.5e-08 33.6 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ85281.1 - 0.0003 19.4 0.3 0.00055 18.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EAQ85282.1 - 1.1e-27 96.9 5.4 1.6e-27 96.4 3.7 1.1 1 0 0 1 1 1 1 RTA1 like protein HXXEE PF13787.1 EAQ85282.1 - 0.038 14.3 1.5 0.038 14.3 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function with HXXEE motif Glyoxalase_2 PF12681.2 EAQ85284.1 - 1.1e-09 38.8 0.0 1.4e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EAQ85284.1 - 5.9e-08 32.7 0.0 7.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SnoaL_4 PF13577.1 EAQ85284.1 - 0.057 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF3437 PF11919.3 EAQ85285.1 - 1.8e-22 78.8 0.2 1e-21 76.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Glyco_hydro_6 PF01341.12 EAQ85285.1 - 0.47 9.8 0.0 0.82 9.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 PIF1 PF05970.9 EAQ85287.1 - 9.9e-06 24.7 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ85287.1 - 0.00028 20.9 0.1 0.00089 19.3 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Pkinase PF00069.20 EAQ85289.1 - 2.5e-35 121.9 0.1 2e-33 115.6 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85289.1 - 1.2e-25 90.1 0.0 1.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-H PF05837.7 EAQ85289.1 - 0.41 10.8 5.3 0.8 9.9 3.7 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) GBP_C PF02841.9 EAQ85289.1 - 1.9 7.5 10.6 2.9 7.0 7.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Complex1_LYR PF05347.10 EAQ85291.1 - 1.4e-12 47.2 0.0 4.9e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ85291.1 - 2.7e-12 46.6 0.2 5.2e-11 42.5 0.0 2.5 2 0 0 2 2 2 1 Complex1_LYR-like UQ_con PF00179.21 EAQ85292.1 - 7.9e-13 48.0 0.0 8.4e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAQ85292.1 - 0.0023 17.7 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 EAQ85293.1 - 9e-36 122.8 0.7 1.1e-34 119.2 0.0 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EAQ85293.1 - 0.00015 21.2 0.0 0.005 16.3 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Band_7 PF01145.20 EAQ85294.1 - 2.4e-31 109.0 1.1 4.2e-31 108.2 0.8 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EAQ85294.1 - 0.025 14.1 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_H PF00075.19 EAQ85295.1 - 2.5e-14 53.7 0.0 4.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EAQ85295.1 - 0.00017 21.2 0.1 0.022 14.5 0.0 3.2 2 1 0 2 2 2 1 Reverse transcriptase-like p450 PF00067.17 EAQ85296.1 - 2.4e-52 177.9 0.0 3.3e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3903 PF13043.1 EAQ85296.1 - 0.15 11.5 0.0 0.15 11.5 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3903) Metallophos_2 PF12850.2 EAQ85297.1 - 2.1e-10 40.6 0.8 6.6e-10 39.0 0.5 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ85297.1 - 2.9e-05 23.5 0.7 0.00098 18.5 0.5 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MACPF PF01823.14 EAQ85299.1 - 1.6e-09 37.7 4.7 3e-09 36.8 1.3 2.1 1 1 1 2 2 2 2 MAC/Perforin domain Fil_haemagg_2 PF13332.1 EAQ85299.1 - 1 9.1 19.9 0.73 9.6 4.9 2.4 2 0 0 2 2 2 0 Haemagluttinin repeat SAP PF02037.22 EAQ85301.1 - 0.18 11.3 4.3 0.19 11.2 0.6 2.5 2 0 0 2 2 2 0 SAP domain RRN3 PF05327.6 EAQ85301.1 - 1.9 6.4 2.8 3.1 5.7 1.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HCV_NS5a_C PF12941.2 EAQ85302.1 - 0.14 11.7 3.1 0.19 11.2 2.2 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region UvrD_C_2 PF13538.1 EAQ85303.1 - 5.5e-05 23.2 0.0 0.00013 22.0 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain p450 PF00067.17 EAQ85304.1 - 1.9e-11 43.1 0.0 2.4e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EpuA PF11772.3 EAQ85304.1 - 0.08 12.3 0.6 1.6 8.1 0.0 2.5 2 1 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Lactamase_B_2 PF12706.2 EAQ85305.1 - 1.2e-13 51.0 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAQ85305.1 - 0.0018 18.0 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAQ85305.1 - 0.0063 16.1 0.6 0.01 15.5 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily YmzC PF14157.1 EAQ85305.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 YmzC-like protein DUF2235 PF09994.4 EAQ85306.1 - 3.2e-48 164.4 0.0 1.9e-29 102.8 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EAQ85306.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EAQ85307.1 - 4.1e-23 81.8 0.0 1.7e-22 79.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85307.1 - 7.8e-11 41.5 0.0 3e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAQ85307.1 - 0.093 11.5 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EAQ85307.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 EAQ85308.1 - 4.3e-21 75.2 0.0 6.7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85308.1 - 4.8e-09 35.6 0.0 8.4e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SlyX PF04102.7 EAQ85312.1 - 1.2 9.5 6.2 0.81 10.1 0.9 3.2 3 1 1 4 4 4 0 SlyX Asparaginase_2 PF01112.13 EAQ85315.1 - 3.1e-39 134.5 3.2 4.5e-18 65.0 0.2 3.3 3 0 0 3 3 3 3 Asparaginase Tim17 PF02466.14 EAQ85316.1 - 1e-26 93.5 6.9 1.2e-26 93.2 4.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M20 PF01546.23 EAQ85317.1 - 2.6e-23 82.5 0.0 6.1e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EAQ85317.1 - 1.6e-21 75.3 0.3 0.00015 21.4 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 EAQ85317.1 - 8.3e-08 31.9 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3639 PF12341.3 EAQ85317.1 - 0.018 15.0 0.1 0.035 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) CNH PF00780.17 EAQ85317.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 CNH domain Peptidase_M28 PF04389.12 EAQ85317.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Nucleoporin_N PF08801.6 EAQ85317.1 - 0.25 10.0 3.6 8.4 5.0 0.6 3.3 2 2 2 4 4 4 0 Nup133 N terminal like Chitin_bind_1 PF00187.14 EAQ85318.1 - 4.6 7.3 24.3 5.4 7.0 15.8 1.9 1 1 1 2 2 2 0 Chitin recognition protein TauD PF02668.11 EAQ85321.1 - 1.2e-41 143.0 0.4 1.6e-41 142.6 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NACHT PF05729.7 EAQ85322.1 - 0.024 14.3 0.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 EAQ85322.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ85322.1 - 0.075 13.8 0.0 0.33 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAQ85322.1 - 0.09 12.9 0.5 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EAQ85322.1 - 0.15 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RVT_1 PF00078.22 EAQ85323.1 - 5.5e-31 107.6 0.0 8.3e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ85323.1 - 1.8e-07 30.8 0.0 4.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ85323.1 - 0.001 19.0 0.2 0.0035 17.3 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EAQ85323.1 - 0.036 14.3 0.2 0.11 12.7 0.2 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase PurS PF02700.9 EAQ85323.1 - 0.043 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Glyco_hydro_18 PF00704.23 EAQ85325.1 - 4.1e-44 151.4 0.0 6.6e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EAQ85325.1 - 4e-07 29.8 0.0 0.034 14.0 0.0 3.3 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 EAQ85325.1 - 0.0036 17.2 4.2 0.0036 17.2 2.9 3.2 3 0 0 3 3 3 1 Chitin recognition protein DUF3142 PF11340.3 EAQ85325.1 - 0.059 13.0 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Carb_anhydrase PF00194.16 EAQ85326.1 - 3.8e-14 52.2 0.0 1.8e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase p450 PF00067.17 EAQ85330.1 - 3.7e-46 157.6 0.0 9.9e-34 116.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 CorA PF01544.13 EAQ85331.1 - 1.2e-05 24.5 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FGase PF05013.7 EAQ85331.1 - 0.046 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase TPR_12 PF13424.1 EAQ85334.1 - 8.9e-17 60.8 11.8 2.5e-09 36.9 0.8 5.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ85334.1 - 1.1e-07 32.1 0.4 0.00045 20.5 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EAQ85334.1 - 2.6e-05 24.3 0.0 0.00063 19.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain TPR_1 PF00515.23 EAQ85334.1 - 3.1e-05 23.3 7.6 0.13 11.8 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ85334.1 - 3.9e-05 23.2 12.6 0.025 14.4 0.6 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ85334.1 - 4.6e-05 23.2 9.4 1.1 9.2 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ85334.1 - 0.00013 20.9 0.0 0.0003 19.7 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EAQ85334.1 - 0.00035 21.1 2.7 0.15 12.7 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ85334.1 - 0.00067 19.2 12.0 0.0014 18.2 0.2 4.0 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.1 EAQ85334.1 - 0.001 19.4 3.9 1.5 9.6 0.2 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ85334.1 - 0.0046 17.0 3.5 1.2 9.3 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 EAQ85334.1 - 0.019 14.4 0.6 0.051 13.0 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 EAQ85334.1 - 0.029 14.9 1.4 0.39 11.4 0.5 3.0 3 0 0 3 3 2 0 Sel1 repeat IstB_IS21 PF01695.12 EAQ85334.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase PF00069.20 EAQ85335.1 - 2.2e-08 33.5 0.0 3.4e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85335.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Amidase PF01425.16 EAQ85337.1 - 4.3e-41 141.2 0.3 6.7e-40 137.2 0.2 2.0 1 1 0 1 1 1 1 Amidase adh_short PF00106.20 EAQ85340.1 - 2.5e-12 47.0 0.1 4.8e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ85340.1 - 8.1e-05 22.3 0.2 0.00021 21.0 0.1 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ85340.1 - 0.00065 19.4 0.6 0.0014 18.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EAQ85340.1 - 0.1 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EAQ85340.1 - 0.11 12.6 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EAQ85340.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Condensation PF00668.15 EAQ85341.1 - 0.00011 21.2 0.2 0.00013 20.9 0.1 1.1 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 EAQ85341.1 - 0.00054 18.6 0.0 0.0006 18.4 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.11 EAQ85341.1 - 0.09 12.3 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain ArsB PF02040.10 EAQ85344.1 - 3.7e-16 59.1 19.2 1.8e-10 40.4 5.3 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Ank_2 PF12796.2 EAQ85345.1 - 5.2e-68 225.4 0.0 1.7e-24 85.9 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ85345.1 - 8.4e-62 202.0 0.2 4.5e-09 35.6 0.0 8.9 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 EAQ85345.1 - 1.6e-40 136.1 0.9 1e-11 44.6 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ85345.1 - 2.1e-40 136.3 0.1 1.7e-10 41.1 0.0 6.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85345.1 - 8.6e-40 130.7 0.0 2.6e-06 27.1 0.0 8.7 8 0 0 8 8 8 7 Ankyrin repeat TPR_14 PF13428.1 EAQ85345.1 - 0.12 13.1 3.9 3.9 8.3 1.5 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ85345.1 - 0.4 10.5 5.9 5.4 7.0 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ85345.1 - 0.44 10.5 3.4 21 5.1 0.6 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.7 EAQ85347.1 - 3.2e-06 26.9 0.1 5.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ85347.1 - 3.9e-06 26.9 0.0 1.6e-05 25.0 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ85347.1 - 0.0003 20.9 0.0 0.0012 18.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAQ85347.1 - 0.0012 17.7 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 EAQ85347.1 - 0.0027 17.4 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Nbas_N PF15492.1 EAQ85347.1 - 0.0064 15.6 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal AAA PF00004.24 EAQ85347.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAQ85347.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ85347.1 - 0.019 15.7 0.0 0.13 13.1 0.0 2.5 3 0 0 3 3 1 0 AAA domain WD40 PF00400.27 EAQ85347.1 - 0.045 13.6 16.2 0.36 10.7 0.0 6.0 6 2 0 6 6 6 0 WD domain, G-beta repeat NTPase_1 PF03266.10 EAQ85347.1 - 0.049 13.3 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 EAQ85347.1 - 0.07 11.8 0.1 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 ArgK protein AAA_25 PF13481.1 EAQ85347.1 - 0.084 12.2 0.0 0.26 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.9 EAQ85348.1 - 1.8e-32 112.4 0.0 2.5e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase RXT2_N PF08595.6 EAQ85348.1 - 0.26 11.0 2.3 0.41 10.4 1.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal MFS_1 PF07690.11 EAQ85349.1 - 2.5e-10 39.5 10.5 3.3e-10 39.2 4.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ85349.1 - 1.7e-07 30.1 1.4 1.7e-07 30.1 0.9 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EAQ85349.1 - 0.016 15.0 1.1 0.045 13.5 0.1 2.2 2 0 0 2 2 2 0 MFS_1 like family MFS_2 PF13347.1 EAQ85349.1 - 0.046 12.1 0.8 0.096 11.0 0.4 1.6 2 0 0 2 2 2 0 MFS/sugar transport protein MtrG PF04210.8 EAQ85349.1 - 1.3 8.7 3.3 0.41 10.3 0.2 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G PP-binding PF00550.20 EAQ85350.1 - 4.6e-14 52.4 0.2 9.8e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site WD40 PF00400.27 EAQ85350.1 - 5.1e-12 45.1 1.7 1.9e-11 43.3 0.4 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat PS-DH PF14765.1 EAQ85350.1 - 1.5e-05 24.2 1.3 1.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase p450 PF00067.17 EAQ85352.1 - 2.9e-23 82.1 0.0 3.4e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phytase-like PF13449.1 EAQ85353.1 - 5.5e-29 101.4 0.0 1.1e-28 100.4 0.0 1.6 2 0 0 2 2 2 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EAQ85353.1 - 0.01 14.7 0.0 0.65 8.8 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated CDC45 PF02724.9 EAQ85354.1 - 7 4.5 6.1 11 3.9 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein MULE PF10551.4 EAQ85356.1 - 2.2e-15 56.6 0.0 4.7e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ85356.1 - 0.0014 19.0 0.3 0.003 18.0 0.2 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 EAQ85356.1 - 0.12 11.9 2.7 0.28 10.7 1.9 1.6 1 0 0 1 1 1 0 SWIM zinc finger Herpeto_peptide PF14409.1 EAQ85358.1 - 0.063 13.0 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon CobT PF06213.7 EAQ85359.1 - 0.097 11.7 4.8 0.12 11.5 3.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2436 PF10365.4 EAQ85360.1 - 0.033 13.8 0.0 0.071 12.7 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2436) hEGF PF12661.2 EAQ85360.1 - 4.4 7.5 6.8 3.8 7.7 0.2 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF Glyco_hydro_31 PF01055.21 EAQ85361.1 - 3.6e-104 349.0 1.5 2e-75 254.3 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Asp PF00026.18 EAQ85361.1 - 2.8e-48 164.7 0.0 4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ85361.1 - 1.2e-06 28.5 0.0 9.7e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ85361.1 - 0.0017 18.7 0.2 1.6 9.2 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EAQ85361.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Response_reg PF00072.19 EAQ85362.1 - 2.5e-07 30.7 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Metallopep PF12044.3 EAQ85363.1 - 6.1e-107 357.7 0.0 1.6e-106 356.3 0.0 1.6 1 1 1 2 2 2 1 Putative peptidase family Glycos_transf_1 PF00534.15 EAQ85365.1 - 1.3e-10 40.9 0.0 4.4e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAQ85365.1 - 3.9e-07 30.3 0.0 7.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAQ85365.1 - 0.0036 17.4 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_hydro_61 PF03443.9 EAQ85366.1 - 4.2e-37 128.0 0.0 1.8e-34 119.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ85366.1 - 1.7e-10 40.3 12.8 1.7e-10 40.3 8.9 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAQ85366.1 - 0.055 13.5 8.8 0.098 12.7 6.1 1.5 1 0 0 1 1 1 0 Toxin 7 MULE PF10551.4 EAQ85369.1 - 9.6e-16 57.7 0.3 8.6e-15 54.6 0.0 2.5 2 1 1 3 3 3 1 MULE transposase domain Transposase_mut PF00872.13 EAQ85369.1 - 0.00015 20.4 0.0 0.00032 19.3 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family mTERF PF02536.9 EAQ85369.1 - 0.036 12.6 0.1 0.081 11.4 0.0 1.6 2 0 0 2 2 2 0 mTERF Cutinase PF01083.17 EAQ85371.1 - 2.3e-34 118.6 0.6 4.6e-29 101.4 0.0 2.1 2 0 0 2 2 2 2 Cutinase VirJ PF06057.6 EAQ85371.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Ank PF00023.25 EAQ85372.1 - 1.4e-40 135.0 4.8 2.8e-06 26.8 0.0 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 EAQ85372.1 - 6.7e-39 132.1 0.0 1.4e-09 38.1 0.1 6.2 3 3 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAQ85372.1 - 4.9e-31 103.6 1.6 0.0016 18.4 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EAQ85372.1 - 1.6e-29 101.6 4.5 7e-08 32.7 0.2 7.4 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ85372.1 - 1.1e-21 76.3 3.2 0.0014 18.8 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeats (many copies) zf-U1 PF06220.7 EAQ85372.1 - 1e-05 24.9 0.1 2.1e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 U1 zinc finger F-box-like PF12937.2 EAQ85372.1 - 5.7e-05 22.7 0.9 0.00013 21.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like DUF3306 PF11748.3 EAQ85372.1 - 0.69 10.5 5.2 0.11 13.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) MARVEL PF01284.18 EAQ85374.1 - 2.9e-06 27.1 18.8 1.7e-05 24.6 13.1 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.7 EAQ85374.1 - 0.61 9.6 11.1 0.032 13.7 2.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF588) DUF3040 PF11239.3 EAQ85374.1 - 1.6 8.7 5.8 0.43 10.6 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Peptidase_M56 PF05569.6 EAQ85374.1 - 1.8 7.4 8.0 0.14 11.1 1.7 1.9 2 1 0 2 2 2 0 BlaR1 peptidase M56 p450 PF00067.17 EAQ85378.1 - 3.1e-40 138.0 0.0 4.3e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAQ85381.1 - 1.8e-27 95.9 0.0 2.4e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAQ85383.1 - 1.5e-20 73.2 0.0 1.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EAQ85384.1 - 1e-41 142.8 54.6 3.6e-41 141.0 36.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily GST_N PF02798.15 EAQ85385.1 - 2.6e-11 43.5 0.0 1.1e-10 41.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ85385.1 - 1.1e-09 38.4 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAQ85385.1 - 4.5e-09 36.1 0.0 7.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAQ85385.1 - 6.3e-09 35.7 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAQ85385.1 - 2.5e-08 33.7 0.3 4.1e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ85385.1 - 1.2e-05 25.6 0.1 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Prenyltrans_1 PF13243.1 EAQ85386.1 - 0.0075 16.2 0.0 0.16 12.0 0.0 2.8 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans PF00432.16 EAQ85386.1 - 0.016 14.7 0.4 0.97 9.0 0.0 3.6 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat DUF2981 PF11200.3 EAQ85386.1 - 0.84 8.6 3.3 1.4 7.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) NTP_transferase PF00483.18 EAQ85387.1 - 1.2e-30 106.6 0.0 1.6e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EAQ85387.1 - 1.8e-08 33.4 3.2 0.00017 20.9 0.0 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EAQ85387.1 - 5.3e-07 29.8 0.0 7.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EAQ85387.1 - 0.015 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_3 PF13641.1 EAQ85387.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Fucokinase PF07959.7 EAQ85387.1 - 0.1 11.1 0.2 0.52 8.8 0.0 2.0 2 0 0 2 2 2 0 L-fucokinase Dynamin_N PF00350.18 EAQ85388.1 - 4.8e-24 85.0 0.0 5.6e-23 81.5 0.0 2.4 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAQ85388.1 - 4.3e-10 38.8 0.1 3.1e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EAQ85388.1 - 0.00038 20.2 0.0 0.00097 18.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAQ85388.1 - 0.0031 17.4 0.0 0.045 13.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EAQ85388.1 - 0.011 15.6 0.1 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EAQ85388.1 - 0.018 15.5 0.0 0.056 13.9 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EAQ85388.1 - 0.02 14.3 0.1 0.068 12.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EAQ85388.1 - 0.024 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Saccharop_dh PF03435.13 EAQ85389.1 - 2.7e-23 82.5 0.0 1.2e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase VWA_2 PF13519.1 EAQ85390.1 - 0.00031 20.9 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain RVT_1 PF00078.22 EAQ85391.1 - 2.8e-10 39.9 0.0 7.2e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EAQ85391.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 RNase H SKG6 PF08693.5 EAQ85392.1 - 0.0038 16.5 1.2 0.0038 16.5 0.9 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EAQ85392.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LAMTOR PF15454.1 EAQ85393.1 - 3e-16 59.4 0.6 4.9e-16 58.7 0.4 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3618 PF12277.3 EAQ85393.1 - 0.094 12.7 0.6 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) RPEL PF02755.10 EAQ85395.1 - 0.00071 18.8 1.6 0.42 9.9 0.0 2.8 3 0 0 3 3 3 2 RPEL repeat zf-C2H2_jaz PF12171.3 EAQ85396.1 - 0.00014 21.9 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAQ85396.1 - 0.008 16.2 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EAQ85396.1 - 0.0093 16.1 0.2 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1974 PF09317.6 EAQ85396.1 - 0.037 13.4 0.5 0.064 12.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) AKAP95 PF04988.7 EAQ85396.1 - 0.13 12.0 0.1 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Fzo_mitofusin PF04799.8 EAQ85396.1 - 0.13 11.6 1.1 0.21 10.9 0.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region Med7 PF05983.6 EAQ85397.1 - 1e-48 165.2 0.0 1.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 MED7 protein RPW8 PF05659.6 EAQ85397.1 - 0.074 12.5 0.1 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Glyoxalase_2 PF12681.2 EAQ85397.1 - 0.089 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain SPOC PF07744.8 EAQ85398.1 - 4.1e-18 65.9 0.0 8.8e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EAQ85398.1 - 7.6e-18 64.6 0.1 2.1e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EAQ85398.1 - 1.7e-09 37.2 8.1 3.2e-09 36.3 5.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EAQ85398.1 - 0.17 11.2 3.4 0.3 10.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.21 EAQ85399.1 - 1.2e-60 204.0 0.1 1.5e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAQ85399.1 - 1.7e-14 52.7 0.4 4.1e-14 51.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EAQ85399.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.16 EAQ85400.1 - 1.2e-21 76.7 1.2 1.2e-21 76.7 0.8 1.6 2 0 0 2 2 2 1 PAP2 superfamily YhhN PF07947.9 EAQ85400.1 - 0.19 11.0 4.9 0.75 9.1 1.5 2.8 2 1 0 2 2 2 0 YhhN-like protein WD40 PF00400.27 EAQ85401.1 - 9.5e-55 180.6 18.3 1.1e-08 34.5 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EAQ85401.1 - 5e-11 42.1 0.2 9.9e-11 41.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ85401.1 - 2.2e-10 39.9 0.6 1e-09 37.7 0.3 2.2 1 1 1 2 2 2 1 F-box domain PQQ_2 PF13360.1 EAQ85401.1 - 0.00057 19.4 0.9 0.059 12.8 0.7 3.1 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 EAQ85401.1 - 0.00093 17.4 7.1 1.9 6.5 0.1 4.9 3 1 1 5 5 5 3 Nucleoporin Nup120/160 PRANC PF09372.5 EAQ85401.1 - 0.046 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 PRANC domain ADH_N PF08240.7 EAQ85403.1 - 3.2e-29 100.8 3.2 5.8e-29 100.0 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ85403.1 - 3.7e-13 49.1 0.0 9.4e-13 47.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EAQ85403.1 - 0.00069 18.8 0.5 0.0011 18.1 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Y_Y_Y PF07495.8 EAQ85403.1 - 0.012 15.3 0.2 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Y_Y_Y domain ETF PF01012.16 EAQ85403.1 - 0.085 12.5 0.0 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 Electron transfer flavoprotein domain Epimerase PF01370.16 EAQ85404.1 - 2.8e-16 59.6 0.1 1e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ85404.1 - 4.7e-12 46.2 0.2 1.9e-11 44.3 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ85404.1 - 5.3e-10 38.4 0.0 1.1e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAQ85404.1 - 1.5e-09 37.1 1.8 7.3e-08 31.6 0.8 2.8 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EAQ85404.1 - 7.3e-09 35.7 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ85404.1 - 3.8e-06 26.6 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EAQ85404.1 - 9e-06 25.1 0.0 4.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EAQ85404.1 - 0.0036 16.2 0.1 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 EAQ85405.1 - 5.1e-109 364.8 17.7 6.4e-109 364.5 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85405.1 - 1.7e-26 92.8 12.6 1.7e-26 92.8 8.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EAQ85405.1 - 0.0015 16.7 6.3 0.01 14.0 0.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Zn_clus PF00172.13 EAQ85406.1 - 1.9e-10 40.4 9.8 3.3e-10 39.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ85406.1 - 3.2e-06 26.2 4.3 9.1e-06 24.7 3.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MR_MLE_C PF13378.1 EAQ85407.1 - 5.9e-10 39.1 0.1 1.5e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EAQ85407.1 - 3.8e-07 30.5 0.0 9.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain GATase PF00117.23 EAQ85408.1 - 0.0002 20.8 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Bd3614_N PF14442.1 EAQ85408.1 - 0.00094 19.1 0.1 0.0015 18.5 0.1 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase N-terminal Sugar_tr PF00083.19 EAQ85409.1 - 6e-73 245.9 24.6 6.8e-73 245.7 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85409.1 - 3.6e-17 62.1 30.9 3.6e-17 62.1 21.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PAN_4 PF14295.1 EAQ85410.1 - 3.7e-06 26.5 0.1 7.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PAN domain Pex14_N PF04695.8 EAQ85410.1 - 0.0015 18.5 9.9 0.14 12.2 0.0 3.2 2 1 1 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region PAN_3 PF08277.7 EAQ85410.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain tRNA-synt_1e PF01406.14 EAQ85412.1 - 4.2e-103 344.6 0.0 7.2e-103 343.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EAQ85412.1 - 0.00039 19.2 1.8 0.12 11.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EAQ85412.1 - 0.0035 17.5 1.5 0.0044 17.2 0.0 2.0 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 EAQ85412.1 - 0.067 11.8 0.0 0.067 11.8 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain DHDPS PF00701.17 EAQ85412.1 - 0.081 11.5 0.1 0.19 10.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Nuc_deoxyrib_tr PF05014.10 EAQ85413.1 - 0.00062 19.6 0.0 0.00074 19.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF3716 PF12511.3 EAQ85414.1 - 3.6e-15 55.3 4.1 7.4e-15 54.3 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Terpene_synth_C PF03936.11 EAQ85416.1 - 0.0026 17.0 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Gpi16 PF04113.9 EAQ85417.1 - 2.5e-253 841.2 0.0 3e-253 840.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FUSC PF04632.7 EAQ85417.1 - 0.038 12.4 0.5 0.051 12.0 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TRAPPC10 PF12584.3 EAQ85417.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 LUC7 PF03194.10 EAQ85418.1 - 5.4e-57 193.2 0.8 2.2e-28 99.5 0.0 2.0 1 1 1 2 2 2 2 LUC7 N_terminus PAT1 PF09770.4 EAQ85419.1 - 0.12 10.6 20.1 0.18 10.0 13.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GMC_oxred_N PF00732.14 EAQ85420.1 - 2.7e-47 161.3 0.0 3.6e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ85420.1 - 1.2e-30 106.7 0.1 2.3e-30 105.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ85420.1 - 0.0005 19.0 0.2 0.0015 17.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ85420.1 - 0.0012 18.8 0.0 0.0041 17.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ85420.1 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Malic_M PF03949.10 EAQ85420.1 - 0.002 17.7 0.1 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Thi4 PF01946.12 EAQ85420.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EAQ85420.1 - 0.0027 16.6 0.0 0.006 15.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EAQ85420.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EAQ85420.1 - 0.041 12.8 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EAQ85420.1 - 0.066 11.8 0.1 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EAQ85420.1 - 0.083 12.7 0.0 0.87 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ85420.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran PF00156.22 EAQ85420.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF498 PF04430.9 EAQ85420.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) TrkA_N PF02254.13 EAQ85420.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain E1_DerP2_DerF2 PF02221.10 EAQ85422.1 - 0.027 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 ML domain Serglycin PF04360.7 EAQ85422.1 - 0.045 13.4 6.9 0.097 12.3 4.8 1.5 1 0 0 1 1 1 0 Serglycin GFO_IDH_MocA PF01408.17 EAQ85423.1 - 9.6e-15 55.1 0.0 1.9e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_5 PF12695.2 EAQ85423.1 - 1.2e-06 28.3 0.4 5.9e-06 26.1 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ85423.1 - 1.8e-05 24.7 5.0 6.5e-05 22.9 3.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family GFO_IDH_MocA_C PF02894.12 EAQ85423.1 - 0.0016 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Abhydrolase_4 PF08386.5 EAQ85424.1 - 7.6e-16 57.8 0.9 2.1e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ85424.1 - 4.3e-14 52.6 0.1 1.7e-13 50.6 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ85424.1 - 1e-07 32.0 2.0 1.8e-07 31.3 0.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1220 PF06758.8 EAQ85424.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) DAO PF01266.19 EAQ85425.1 - 3.1e-15 55.9 3.9 1.1e-14 54.2 2.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EAQ85425.1 - 0.0083 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 EAQ85425.1 - 0.012 15.6 0.1 0.068 13.1 0.0 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EAQ85425.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 EAQ85426.1 - 1.9e-56 191.5 0.0 6.5e-56 189.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EAQ85427.1 - 6.9e-09 35.3 0.0 1.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Epimerase PF01370.16 EAQ85427.1 - 0.00029 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ85427.1 - 0.0067 15.3 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EAQ85427.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Sec63 PF02889.11 EAQ85428.1 - 3.3e-29 102.1 0.0 5.8e-24 84.8 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EAQ85428.1 - 6.9e-28 97.2 0.0 1.3e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ85428.1 - 6.2e-10 38.7 0.0 3.8e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ85428.1 - 3.9e-09 36.5 0.0 8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EAQ85428.1 - 0.0015 17.8 0.1 0.05 12.9 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain T2SE PF00437.15 EAQ85428.1 - 0.0092 14.9 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EAQ85428.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EAQ85428.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ85428.1 - 0.038 13.7 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain HHH_5 PF14520.1 EAQ85428.1 - 0.072 13.2 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain NACHT PF05729.7 EAQ85429.1 - 2.9e-11 43.3 0.3 4.8e-11 42.6 0.2 1.3 1 0 0 1 1 1 1 NACHT domain FAP PF07174.6 EAQ85429.1 - 4.5 6.4 17.3 7.6 5.7 12.0 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Exo_endo_phos PF03372.18 EAQ85431.1 - 2e-11 44.2 0.1 3e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4500 PF14937.1 EAQ85432.1 - 0.036 13.8 0.1 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Nuc_sug_transp PF04142.10 EAQ85434.1 - 1.3e-79 266.7 4.5 1.8e-79 266.3 3.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EAQ85434.1 - 5.5e-10 38.6 10.2 5.1e-09 35.4 7.0 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EAQ85434.1 - 8.5e-08 31.9 17.2 0.00052 19.6 0.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EAQ85434.1 - 2.3e-05 24.4 23.0 0.00023 21.2 3.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EAQ85434.1 - 0.00067 19.8 1.2 0.00067 19.8 0.8 2.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF4448 PF14610.1 EAQ85436.1 - 1.3e-06 28.0 0.0 1.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Adhesin_P1 PF03257.8 EAQ85436.1 - 0.08 13.2 1.2 0.43 10.9 0.8 2.1 1 1 0 1 1 1 0 Mycoplasma adhesin P1 zf-CCHC PF00098.18 EAQ85439.1 - 0.038 13.9 7.4 0.2 11.6 3.7 2.7 2 0 0 2 2 2 0 Zinc knuckle NHL PF01436.16 EAQ85440.1 - 0.014 15.3 0.0 23 5.2 0.0 4.2 4 0 0 4 4 4 0 NHL repeat LysM PF01476.15 EAQ85442.1 - 1.2e-40 137.1 0.0 2.5e-10 40.0 0.0 6.3 6 0 0 6 6 6 6 LysM domain Glyco_hydro_18 PF00704.23 EAQ85443.1 - 7.4e-70 236.0 0.1 1e-69 235.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EAQ85443.1 - 1.8e-08 34.2 7.7 1.8e-08 34.2 5.4 5.1 4 0 0 4 4 4 2 Chitin recognition protein Acetyltransf_2 PF00797.12 EAQ85444.1 - 1.4e-48 165.5 0.0 2e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 EAQ85444.1 - 0.0059 16.7 0.1 0.012 15.7 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily p450 PF00067.17 EAQ85445.1 - 3.3e-42 144.5 0.0 4.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HTH_29 PF13551.1 EAQ85445.1 - 0.7 10.0 3.2 1.8 8.7 0.6 2.7 3 1 1 4 4 4 0 Winged helix-turn helix VCBS PF13517.1 EAQ85446.1 - 5.6e-27 93.8 43.3 7.6e-13 48.6 1.4 7.9 4 2 4 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAQ85446.1 - 1.4e-16 59.6 30.2 0.0015 18.1 0.8 7.3 6 0 0 6 6 6 6 FG-GAP repeat Lipase_GDSL PF00657.17 EAQ85446.1 - 3.2e-16 59.8 0.2 8.2e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAQ85446.1 - 2.4e-14 53.8 0.4 7e-13 49.1 0.4 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EAQ85446.1 - 0.00057 19.6 0.4 0.0053 16.5 0.3 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 EAQ85446.1 - 0.0073 15.7 13.9 1.6 8.1 0.1 5.9 4 2 3 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region PI-PLC-X PF00388.14 EAQ85446.1 - 0.037 13.4 0.0 0.094 12.1 0.0 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Pectate_lyase_3 PF12708.2 EAQ85448.1 - 3.6e-80 269.2 10.7 5.9e-66 222.7 2.1 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.1 EAQ85448.1 - 1e-06 28.5 7.6 6.7e-06 25.9 3.2 2.6 2 0 0 2 2 2 1 Right handed beta helix region End_N_terminal PF12218.3 EAQ85448.1 - 7.2e-06 25.3 1.6 0.085 12.3 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase AF-4 PF05110.8 EAQ85448.1 - 3.2 5.5 11.6 4.5 5.0 8.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Flu_M1_C PF08289.6 EAQ85453.1 - 0.081 12.9 0.3 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Acetyltransf_1 PF00583.19 EAQ85454.1 - 2.8e-09 36.8 0.0 5.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAQ85454.1 - 8.6e-05 22.6 0.0 0.00069 19.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAQ85454.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAQ85454.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1996 PF09362.5 EAQ85456.1 - 2.4e-90 302.3 0.4 2.9e-90 302.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NMD3 PF04981.8 EAQ85456.1 - 0.11 11.5 0.1 0.48 9.5 0.0 1.8 2 0 0 2 2 2 0 NMD3 family MFS_1 PF07690.11 EAQ85457.1 - 2.9e-21 75.5 50.8 1.5e-20 73.2 32.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ85457.1 - 8.7e-08 30.8 25.3 1.3e-07 30.2 17.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ECH PF00378.15 EAQ85458.1 - 2.6e-44 151.1 0.1 2.3e-30 105.5 0.1 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family S-AdoMet_synt_C PF02773.11 EAQ85458.1 - 0.11 12.2 0.3 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain DoxD PF04173.8 EAQ85458.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 TQO small subunit DoxD Acetyltransf_8 PF13523.1 EAQ85459.1 - 2.1e-31 108.8 0.0 3.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EAQ85460.1 - 8.8e-75 251.6 22.7 2.1e-42 145.4 2.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ85460.1 - 1.1e-62 210.2 0.0 4.9e-32 111.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAQ85460.1 - 2.7e-14 52.9 1.1 0.0009 18.5 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ85460.1 - 1.1e-10 41.9 0.1 0.075 12.9 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EAQ85460.1 - 5.7e-09 35.3 0.2 0.0018 17.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAQ85460.1 - 6.9e-08 32.6 3.6 0.0059 16.6 0.5 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAQ85460.1 - 6.3e-07 29.5 0.2 0.31 11.1 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EAQ85460.1 - 7.2e-07 30.0 0.0 0.056 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EAQ85460.1 - 1.8e-06 26.8 0.9 0.014 14.0 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_30 PF13604.1 EAQ85460.1 - 2e-06 27.5 1.6 0.21 11.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.12 EAQ85460.1 - 1.6e-05 24.8 0.1 0.015 15.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 EAQ85460.1 - 2.9e-05 23.3 0.0 0.034 13.3 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAQ85460.1 - 4.6e-05 22.9 4.1 0.13 11.6 0.0 4.3 5 0 0 5 5 5 1 AAA domain AAA_23 PF13476.1 EAQ85460.1 - 0.00018 21.8 0.4 0.28 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAQ85460.1 - 0.0002 21.2 0.1 1 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EAQ85460.1 - 0.0005 19.9 0.9 2.4 8.1 0.0 3.7 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EAQ85460.1 - 0.00051 19.2 0.0 0.14 11.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EAQ85460.1 - 0.00052 19.5 0.7 0.26 10.6 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EAQ85460.1 - 0.0011 19.3 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EAQ85460.1 - 0.0016 18.6 0.4 17 5.6 0.1 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EAQ85460.1 - 0.0035 16.8 0.1 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family APS_kinase PF01583.15 EAQ85460.1 - 0.0046 16.6 0.0 3.8 7.1 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase SRP54 PF00448.17 EAQ85460.1 - 0.012 15.0 0.0 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EAQ85460.1 - 0.012 15.3 0.0 4.2 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.1 EAQ85460.1 - 0.022 13.3 0.1 4.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MobB PF03205.9 EAQ85460.1 - 0.026 14.2 0.1 9.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EAQ85460.1 - 0.029 14.3 0.1 5 7.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EAQ85460.1 - 0.11 11.6 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 EAQ85460.1 - 0.31 9.8 0.1 15 4.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Condensation PF00668.15 EAQ85461.1 - 5.1e-64 215.9 0.0 4.7e-31 107.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.23 EAQ85461.1 - 9.4e-50 169.1 0.0 7.6e-49 166.2 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EAQ85461.1 - 1.6e-25 89.1 0.0 9.7e-12 44.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Vitellogenin_N PF01347.17 EAQ85461.1 - 1.1 7.3 0.0 1.7 6.7 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region DUF1749 PF08538.5 EAQ85462.1 - 1.4e-66 224.4 0.0 1.5e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EAQ85462.1 - 1.8e-05 24.7 0.6 2.2e-05 24.4 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ85462.1 - 0.00011 21.9 0.1 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ85462.1 - 0.00064 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 EAQ85462.1 - 0.049 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF900 PF05990.7 EAQ85462.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Excalibur PF05901.6 EAQ85462.1 - 5 7.5 6.8 34 4.8 0.0 2.9 2 1 0 2 2 2 0 Excalibur calcium-binding domain Fructosamin_kin PF03881.9 EAQ85463.1 - 7.2e-22 77.6 0.0 9.9e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 EAQ85463.1 - 0.033 12.8 0.0 0.059 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.18 EAQ85463.1 - 0.05 13.3 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MULE PF10551.4 EAQ85464.1 - 9.8e-16 57.7 0.3 8.6e-15 54.6 0.0 2.5 2 1 1 3 3 3 1 MULE transposase domain Transposase_mut PF00872.13 EAQ85464.1 - 0.00016 20.3 0.0 0.00032 19.3 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family mTERF PF02536.9 EAQ85464.1 - 0.035 12.7 0.0 0.081 11.4 0.0 1.5 1 0 0 1 1 1 0 mTERF SHMT PF00464.14 EAQ85465.1 - 7.8e-24 83.7 0.0 9.4e-24 83.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase TMF_TATA_bd PF12325.3 EAQ85465.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4360 PF14273.1 EAQ85468.1 - 1.2e-12 47.8 0.1 6.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) RTA1 PF04479.8 EAQ85469.1 - 1.9e-56 191.0 4.2 2.5e-56 190.6 2.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2207 PF09972.4 EAQ85469.1 - 3.8 5.9 5.3 11 4.4 0.0 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) HEAT_EZ PF13513.1 EAQ85470.1 - 2.8e-21 75.3 6.2 1.3e-06 28.7 0.0 10.9 10 2 2 12 12 12 3 HEAT-like repeat HEAT PF02985.17 EAQ85470.1 - 7e-16 56.8 6.3 0.01 15.8 0.0 9.4 11 0 0 11 11 9 3 HEAT repeat HEAT_2 PF13646.1 EAQ85470.1 - 3.3e-13 49.7 21.5 0.0005 20.2 0.1 8.6 3 2 7 10 10 10 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EAQ85470.1 - 1.8e-06 28.2 0.1 0.77 10.1 0.0 5.2 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EAQ85470.1 - 1.7e-05 24.5 0.0 0.22 11.2 0.0 3.9 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 EAQ85470.1 - 3.4e-05 23.7 0.2 0.3 10.9 0.0 4.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EAQ85470.1 - 7.3e-05 22.2 0.5 0.0036 16.6 0.0 3.5 4 0 0 4 4 4 1 CLASP N terminal IBN_N PF03810.14 EAQ85470.1 - 0.00091 19.0 3.5 0.01 15.7 0.2 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 EAQ85470.1 - 0.0023 17.6 5.6 73 3.3 0.0 7.5 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EAQ85470.1 - 0.0032 16.7 1.4 0.21 10.7 0.0 3.8 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II YukD PF08817.5 EAQ85470.1 - 0.09 13.3 1.4 4.5 7.9 0.0 3.7 4 0 0 4 4 3 0 WXG100 protein secretion system (Wss), protein YukD Cerato-platanin PF07249.7 EAQ85471.1 - 1.1e-06 28.5 0.6 1.1e-06 28.5 0.4 1.7 2 0 0 2 2 2 1 Cerato-platanin NUDIX PF00293.23 EAQ85472.1 - 8.5e-14 51.3 0.8 1.1e-13 50.9 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_1d PF00750.14 EAQ85473.1 - 3.5e-37 128.0 0.3 1.2e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) RVT_1 PF00078.22 EAQ85473.1 - 1.6e-11 43.9 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DALR_1 PF05746.10 EAQ85473.1 - 7.4e-10 38.8 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 DALR anticodon binding domain DUF1996 PF09362.5 EAQ85474.1 - 1.2e-48 165.8 0.0 1.6e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NMD3 PF04981.8 EAQ85474.1 - 0.068 12.2 0.3 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 NMD3 family PIF1 PF05970.9 EAQ85475.1 - 9.2e-19 67.5 0.1 1.7e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase Dimer_Tnp_hAT PF05699.9 EAQ85475.1 - 1.1e-16 60.2 0.4 2.9e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region AAA_30 PF13604.1 EAQ85475.1 - 9.1e-06 25.3 0.2 2.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ85475.1 - 0.0006 19.9 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Ank PF00023.25 EAQ85477.1 - 4.9e-18 63.9 4.2 3.6e-10 39.1 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EAQ85477.1 - 1.5e-17 63.6 0.0 4e-17 62.3 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ85477.1 - 5.9e-12 45.7 1.1 4.3e-07 30.2 0.2 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ85477.1 - 6.6e-12 45.2 0.6 3e-11 43.1 0.1 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85477.1 - 3.9e-11 42.0 0.0 5.2e-06 26.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Abhydrolase_3 PF07859.8 EAQ85480.1 - 1.1e-41 142.7 0.0 1.5e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EAQ85480.1 - 2e-06 26.8 0.0 2.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 EAQ85480.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase tRNA-synt_2 PF00152.15 EAQ85481.1 - 3.2e-75 252.9 0.0 4.8e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EAQ85481.1 - 6.3e-24 84.3 0.0 9.5e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EAQ85481.1 - 3.4e-05 23.6 0.1 7.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAQ85481.1 - 0.00055 19.2 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4309 PF14172.1 EAQ85482.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) DUF945 PF06097.6 EAQ85482.1 - 0.088 11.5 0.7 0.12 11.1 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) GMC_oxred_N PF00732.14 EAQ85483.1 - 2.7e-51 174.4 0.0 3.3e-50 170.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ85483.1 - 7e-33 113.9 0.0 1.3e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAQ85483.1 - 1.8e-06 27.1 3.8 0.00066 18.6 0.1 2.6 4 0 0 4 4 4 2 FAD binding domain DAO PF01266.19 EAQ85483.1 - 2.8e-06 26.4 0.6 0.0045 15.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ85483.1 - 0.00045 20.1 0.0 0.036 13.9 0.1 3.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ85483.1 - 0.0013 17.3 0.0 0.13 10.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EAQ85483.1 - 0.0017 18.3 0.9 0.0036 17.2 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ85483.1 - 0.0027 17.7 5.5 0.018 15.1 0.1 3.4 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ85483.1 - 0.003 16.6 0.1 0.0086 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EAQ85483.1 - 0.041 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EAQ85483.1 - 0.044 13.7 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EAQ85483.1 - 0.062 12.3 0.1 0.18 10.9 0.1 1.7 1 0 0 1 1 1 0 Thi4 family DUF4283 PF14111.1 EAQ85486.1 - 0.15 11.1 0.2 0.16 11.0 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) Sugar_tr PF00083.19 EAQ85487.1 - 2.4e-32 112.1 22.6 1.3e-21 76.7 3.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85487.1 - 1.1e-17 63.8 30.5 9.9e-11 40.9 13.8 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3384 PF11864.3 EAQ85488.1 - 0.019 13.4 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) FUSC PF04632.7 EAQ85488.1 - 0.48 8.8 2.0 0.66 8.3 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Methyltransf_2 PF00891.13 EAQ85490.1 - 7e-27 94.1 0.1 2.1e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase MarR_2 PF12802.2 EAQ85490.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 MarR family NSP11 PF06471.7 EAQ85490.1 - 0.18 9.9 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 NSP11 Ank PF00023.25 EAQ85492.1 - 1.9e-17 62.0 4.8 1e-06 28.2 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 EAQ85492.1 - 8.9e-17 61.2 0.2 1.3e-11 44.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAQ85492.1 - 2.3e-11 42.7 0.5 0.015 15.5 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EAQ85492.1 - 6.7e-10 38.8 0.7 0.16 12.2 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ85492.1 - 9.2e-09 35.5 0.3 0.0017 18.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EAQ85492.1 - 0.0013 18.3 0.1 0.0041 16.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ85492.1 - 0.0077 15.8 0.2 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain Abhydrolase_6 PF12697.2 EAQ85493.1 - 9.6e-12 45.2 0.0 1.7e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ85493.1 - 2.9e-05 23.8 0.3 5.3e-05 22.9 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAQ85493.1 - 0.0086 15.6 0.0 0.02 14.5 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EAQ85493.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 EAQ85493.1 - 0.043 13.3 0.1 0.053 13.0 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DNA_pol3_a_NI PF14480.1 EAQ85494.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III polC-type N-terminus I Sec2p PF06428.6 EAQ85494.1 - 0.0081 15.9 3.8 0.0081 15.9 2.7 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 EAQ85494.1 - 1.8 8.1 6.7 0.73 9.3 2.0 2.1 2 0 0 2 2 2 0 IncA protein Mer2 PF09074.5 EAQ85495.1 - 0.00017 21.6 1.0 0.00029 20.8 0.7 1.3 1 0 0 1 1 1 1 Mer2 Herpes_UL6 PF01763.11 EAQ85495.1 - 0.058 11.5 0.9 0.09 10.9 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF948 PF06103.6 EAQ85495.1 - 0.063 13.1 1.8 0.13 12.1 1.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EAQ85495.1 - 0.095 13.0 6.1 0.22 11.9 3.5 2.1 1 1 0 1 1 1 0 SlyX TBPIP PF07106.8 EAQ85495.1 - 0.15 11.6 2.8 0.35 10.3 1.9 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ADIP PF11559.3 EAQ85495.1 - 2.4 8.0 11.6 0.073 12.9 3.5 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.20 EAQ85497.1 - 4.7e-47 160.3 0.0 7.2e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85497.1 - 9.4e-19 67.4 0.0 2e-18 66.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EAQ85497.1 - 8.9e-11 41.7 0.2 1.9e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 FHA domain SAICAR_synt PF01259.13 EAQ85498.1 - 3.4e-21 75.4 0.0 2.5e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 SAICAR synthetase 2-Hacid_dh_C PF02826.14 EAQ85499.1 - 4.1e-44 149.8 0.0 5.2e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ85499.1 - 0.00037 19.9 0.0 0.001 18.5 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MULE PF10551.4 EAQ85500.1 - 4.9e-15 55.4 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ85500.1 - 0.0011 17.6 0.0 0.0019 16.8 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family PIF1 PF05970.9 EAQ85501.1 - 7.5e-19 67.8 0.0 1.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ85501.1 - 2.9e-06 27.0 0.2 7.4e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ85501.1 - 0.00028 20.9 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ85501.1 - 0.011 15.8 0.1 0.031 14.3 0.1 1.8 1 0 0 1 1 1 0 Helicase associated domain UvrD_C_2 PF13538.1 EAQ85502.1 - 7.8e-05 22.7 0.0 0.00031 20.8 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ85502.1 - 0.013 15.6 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain PIF1 PF05970.9 EAQ85502.1 - 0.087 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase CN_hydrolase PF00795.17 EAQ85504.1 - 1.1e-28 99.8 0.1 1.5e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PAF-AH_p_II PF03403.8 EAQ85505.1 - 6.3e-22 77.3 0.0 2.1e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EAQ85505.1 - 4.2e-16 58.9 0.2 6.2e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ85505.1 - 3.8e-08 33.4 1.4 7.7e-08 32.4 1.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EAQ85505.1 - 0.00042 19.2 0.0 0.001 17.9 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EAQ85505.1 - 0.00084 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EAQ85505.1 - 0.0013 17.9 0.1 0.0048 16.1 0.0 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EAQ85505.1 - 0.002 17.7 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EAQ85505.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EAQ85506.1 - 2.1e-19 69.4 40.7 2.1e-19 69.4 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DoxD PF04173.8 EAQ85506.1 - 0.087 12.4 4.4 0.57 9.8 3.0 2.3 1 1 0 1 1 1 0 TQO small subunit DoxD OATP PF03137.15 EAQ85506.1 - 3.5 5.5 10.5 0.73 7.8 2.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.16 EAQ85507.1 - 1e-22 80.7 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ85507.1 - 1.1e-12 47.3 0.0 1.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EAQ85507.1 - 2.1e-11 44.1 0.4 7.8e-11 42.3 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EAQ85507.1 - 3.1e-08 32.8 0.1 1e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EAQ85507.1 - 1.7e-05 24.8 3.0 8.9e-05 22.4 0.7 2.7 1 1 1 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EAQ85507.1 - 7e-05 22.1 0.2 0.00014 21.2 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EAQ85507.1 - 0.00016 21.3 0.7 0.0028 17.3 0.4 2.4 1 1 0 1 1 1 1 KR domain FAD_binding_4 PF01565.18 EAQ85508.1 - 7.8e-17 61.0 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GFO_IDH_MocA PF01408.17 EAQ85509.1 - 1.1e-14 54.9 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EAQ85509.1 - 0.017 15.4 0.1 0.035 14.4 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.11 EAQ85512.1 - 2.6e-07 29.6 25.7 2.6e-07 29.6 17.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ATPase_gene1 PF09527.5 EAQ85512.1 - 0.026 14.3 5.8 3.3 7.5 0.5 3.9 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF3278 PF11683.3 EAQ85512.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Asp PF00026.18 EAQ85513.1 - 7.6e-22 77.9 0.0 4.9e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EAQ85513.1 - 1.9e-06 28.2 0.0 0.84 10.1 0.0 3.3 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.1 EAQ85513.1 - 0.017 14.9 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 EAQ85513.1 - 0.031 14.1 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease p450 PF00067.17 EAQ85514.1 - 4.8e-67 226.4 0.0 6.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EAQ85515.1 - 3.9e-54 183.9 13.1 1.2e-43 149.3 3.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85515.1 - 3.4e-09 35.8 25.9 4.8e-07 28.8 20.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ85515.1 - 0.00078 17.7 1.1 0.0011 17.2 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EAQ85515.1 - 6.1 5.1 23.1 0.063 11.6 6.6 2.8 3 1 1 4 4 4 0 MFS/sugar transport protein p450 PF00067.17 EAQ85516.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 FAD_binding_3 PF01494.14 EAQ85517.1 - 7.3e-09 35.1 0.6 5.3e-08 32.3 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain Aldedh PF00171.17 EAQ85518.1 - 2.3e-157 524.0 0.8 2.6e-157 523.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EAQ85518.1 - 0.013 14.7 0.0 0.89 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Amidohydro_2 PF04909.9 EAQ85519.1 - 2.5e-30 105.9 0.3 4.2e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase DUF3439 PF11921.3 EAQ85519.1 - 0.85 9.3 6.9 1.6 8.4 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AzlC PF03591.9 EAQ85520.1 - 0.00021 21.2 0.7 0.00034 20.5 0.5 1.3 1 0 0 1 1 1 1 AzlC protein DLH PF01738.13 EAQ85522.1 - 1.3e-30 106.3 0.1 1.5e-30 106.1 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAQ85522.1 - 5e-08 32.8 0.0 7.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PSI_PSAK PF01241.13 EAQ85522.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK DUF915 PF06028.6 EAQ85522.1 - 0.051 12.6 0.0 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) AAA_31 PF13614.1 EAQ85522.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF747 PF05346.6 EAQ85523.1 - 1e-134 448.8 0.5 1.5e-134 448.2 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family WW PF00397.21 EAQ85524.1 - 5.2e-09 35.8 4.8 5.2e-09 35.8 3.4 2.6 3 0 0 3 3 3 1 WW domain FF PF01846.14 EAQ85524.1 - 1.8e-07 30.9 1.6 5.3e-07 29.4 0.1 2.6 3 0 0 3 3 3 1 FF domain PIF1 PF05970.9 EAQ85524.1 - 0.00027 20.0 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase SSP160 PF06933.6 EAQ85527.1 - 0.01 13.8 7.8 0.013 13.5 5.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SpoIIIAH PF12685.2 EAQ85527.1 - 0.097 12.1 0.2 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Herpes_US9 PF06072.6 EAQ85527.1 - 0.14 12.0 0.8 0.26 11.1 0.6 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Alpha_GJ PF03229.8 EAQ85527.1 - 1.1 9.6 10.2 1.7 8.9 7.1 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1628 PF07790.6 EAQ85527.1 - 1.7 9.4 5.4 42 5.0 3.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) K_oxygenase PF13434.1 EAQ85528.1 - 2.1e-49 168.2 0.0 8.1e-32 110.4 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EAQ85528.1 - 0.049 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding AMP-binding PF00501.23 EAQ85529.1 - 6.4e-254 841.7 0.0 1.6e-91 306.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EAQ85529.1 - 6.6e-167 553.8 0.0 4e-32 111.2 0.0 6.8 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EAQ85529.1 - 5.1e-53 177.2 14.8 3.9e-09 36.6 0.1 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ85529.1 - 3.7e-14 53.4 0.1 0.00083 20.2 0.0 4.4 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Mur_ligase PF01225.20 EAQ85529.1 - 0.043 13.8 0.0 0.93 9.6 0.0 2.8 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Transferase PF02458.10 EAQ85529.1 - 0.18 10.2 0.3 2.7 6.3 0.0 2.7 3 0 0 3 3 3 0 Transferase family SH3_1 PF00018.23 EAQ85530.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ85530.1 - 0.01 15.3 0.1 0.024 14.1 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain zf-H2C2_5 PF13909.1 EAQ85530.1 - 0.013 15.6 0.2 0.013 15.6 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain SH3_9 PF14604.1 EAQ85530.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain zf-C2H2 PF00096.21 EAQ85530.1 - 0.26 11.7 10.1 0.16 12.3 0.7 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ85530.1 - 0.35 11.3 8.3 2.2 8.8 0.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1264 PF06884.6 EAQ85531.1 - 5.9e-74 247.1 0.0 7e-74 246.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) HpcH_HpaI PF03328.9 EAQ85534.1 - 3e-20 72.0 0.0 1.1e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EAQ85534.1 - 0.028 13.0 0.1 0.066 11.8 0.0 1.6 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain VIT1 PF01988.14 EAQ85535.1 - 0.004 16.6 0.8 0.0057 16.1 0.5 1.2 1 0 0 1 1 1 1 VIT family EHN PF06441.7 EAQ85536.1 - 1.1e-37 128.3 0.3 2.7e-37 127.0 0.0 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EAQ85536.1 - 1.1e-11 45.0 4.7 2.1e-11 44.1 3.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ85536.1 - 5.6e-08 32.6 0.1 3.6e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_16 PF00722.16 EAQ85537.1 - 6.5e-13 48.3 1.9 1.2e-12 47.5 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.13 EAQ85537.1 - 2e-09 36.9 13.3 2e-09 36.9 9.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Nop14 PF04147.7 EAQ85538.1 - 6.8 4.4 8.0 9 4.0 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family AAA PF00004.24 EAQ85541.1 - 3.6e-15 56.3 0.0 1.5e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ85541.1 - 0.00051 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ85541.1 - 0.0021 18.1 0.0 0.0076 16.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ85541.1 - 0.0059 16.3 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EAQ85541.1 - 0.0062 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EAQ85541.1 - 0.0065 17.2 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ85541.1 - 0.092 12.6 0.0 0.5 10.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 EAQ85541.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAQ85541.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EAQ85541.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus cobW PF02492.14 EAQ85541.1 - 0.38 10.1 0.0 0.57 9.5 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helitron_like_N PF14214.1 EAQ85542.1 - 2.6e-23 82.7 0.0 4.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ85542.1 - 1.7e-08 33.8 0.0 0.0026 16.7 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ85542.1 - 0.001 16.9 0.0 0.0015 16.3 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ85542.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ASCH PF04266.9 EAQ85543.1 - 3.6e-11 43.3 0.0 4.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 ASCH domain zf-LITAF-like PF10601.4 EAQ85544.1 - 4.2e-13 48.9 12.7 5.6e-13 48.5 8.8 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.1 EAQ85544.1 - 0.00086 18.7 1.3 0.018 14.4 0.1 2.3 2 0 0 2 2 2 1 Cysteine-rich KTR NOB1_Zn_bind PF08772.6 EAQ85544.1 - 0.012 15.4 7.8 0.63 9.8 3.8 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FAP PF07174.6 EAQ85544.1 - 8.7 5.5 19.3 13 4.9 13.4 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) IF-2B PF01008.12 EAQ85547.1 - 9.7e-15 54.2 0.0 1.7e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 EAQ85547.1 - 4.9e-10 39.1 0.3 1.4e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Fungal_trans PF04082.13 EAQ85548.1 - 1.8e-10 40.1 0.0 3.6e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ85548.1 - 6.7e-06 25.9 9.8 1.5e-05 24.8 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleotid_trans PF03407.11 EAQ85549.1 - 1.7e-07 31.2 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 EAQ85549.1 - 0.035 13.5 0.4 0.051 13.0 0.3 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Lactamase_B_2 PF12706.2 EAQ85550.1 - 0.0009 18.8 0.1 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAQ85550.1 - 0.0074 15.9 10.5 0.083 12.5 1.5 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Exo_endo_phos_2 PF14529.1 EAQ85551.1 - 4.2e-10 39.2 0.0 9.3e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EAQ85551.1 - 0.00014 21.5 3.7 0.00032 20.4 2.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Exo_endo_phos PF03372.18 EAQ85551.1 - 0.00015 21.7 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EAQ85551.1 - 0.0035 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PurS PF02700.9 EAQ85551.1 - 0.026 14.4 0.0 0.08 12.9 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase zf-CCHC_4 PF14392.1 EAQ85551.1 - 0.45 10.2 1.9 0.8 9.4 0.5 2.1 3 0 0 3 3 3 0 Zinc knuckle Prominin PF05478.6 EAQ85551.1 - 0.63 7.5 0.7 0.99 6.8 0.5 1.2 1 0 0 1 1 1 0 Prominin zf-CCHC_3 PF13917.1 EAQ85551.1 - 0.7 9.6 6.1 0.84 9.4 2.3 2.3 2 0 0 2 2 2 0 Zinc knuckle PIF1 PF05970.9 EAQ85553.1 - 2.5e-07 29.9 0.0 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ85553.1 - 0.014 13.2 0.0 0.019 12.7 0.0 1.1 1 0 0 1 1 1 0 Helicase UvrD_C_2 PF13538.1 EAQ85553.1 - 0.043 13.9 0.0 0.35 11.0 0.0 2.4 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain PAN_4 PF14295.1 EAQ85555.1 - 1.2e-05 24.9 0.3 2.1e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EAQ85555.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_2 PF08276.6 EAQ85555.1 - 0.043 13.6 0.2 0.085 12.7 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain MacB_PCD PF12704.2 EAQ85555.1 - 0.073 12.6 0.5 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 MacB-like periplasmic core domain Sugar_tr PF00083.19 EAQ85556.1 - 2.5e-57 194.4 2.2 3.1e-57 194.1 1.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85556.1 - 2.3e-22 79.2 3.8 2.6e-22 79.0 2.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ85556.1 - 0.00038 18.9 0.3 0.0026 16.2 0.0 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EAQ85556.1 - 0.00077 17.7 0.7 0.0011 17.2 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M30 PF10460.4 EAQ85556.1 - 0.0062 15.4 0.3 0.0089 14.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase M30 DUF4188 PF13826.1 EAQ85557.1 - 1.5e-34 118.5 0.0 2.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EAQ85557.1 - 0.092 11.7 0.1 0.37 9.7 0.1 1.7 1 1 1 2 2 2 0 Haem-containing dehydratase Dimer_Tnp_hAT PF05699.9 EAQ85558.1 - 3e-19 68.4 0.2 4.5e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_1 PF03184.14 EAQ85559.1 - 4.6e-46 156.6 0.0 7.1e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ85559.1 - 1.1e-11 44.0 0.0 2.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ85559.1 - 6.7e-08 32.2 0.1 3.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ85559.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D zf-CCHC PF00098.18 EAQ85559.1 - 0.057 13.3 1.1 0.11 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EAQ85559.1 - 0.076 12.6 1.9 0.15 11.7 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF904 PF06005.7 EAQ85559.1 - 0.087 13.1 1.7 0.38 11.0 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) YPEB PF14620.1 EAQ85560.1 - 0.0036 16.3 0.1 0.0045 16.0 0.1 1.1 1 0 0 1 1 1 1 YpeB sporulation OmpH PF03938.9 EAQ85560.1 - 0.0043 17.0 2.5 0.0066 16.3 1.7 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Transposase_22 PF02994.9 EAQ85560.1 - 0.0064 15.0 0.2 0.0094 14.4 0.1 1.3 1 0 0 1 1 1 1 L1 transposable element Laminin_II PF06009.7 EAQ85560.1 - 0.0069 16.1 1.1 0.86 9.3 0.2 2.2 2 0 0 2 2 2 1 Laminin Domain II Atg14 PF10186.4 EAQ85560.1 - 0.0094 14.9 1.4 0.013 14.4 1.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EAQ85560.1 - 0.0098 15.6 3.3 0.017 14.8 2.3 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein KfrA_N PF11740.3 EAQ85560.1 - 0.011 16.1 5.4 0.011 16.1 3.7 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term COG2 PF06148.6 EAQ85560.1 - 0.015 15.1 1.5 0.03 14.2 1.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.14 EAQ85560.1 - 0.016 14.7 0.7 0.03 13.8 0.5 1.4 1 0 0 1 1 1 0 GrpE WXG100 PF06013.7 EAQ85560.1 - 0.017 15.0 1.4 0.028 14.4 0.3 1.8 2 0 0 2 2 1 0 Proteins of 100 residues with WXG FKBP_N PF01346.13 EAQ85560.1 - 0.02 14.9 1.4 0.046 13.7 1.0 1.6 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PilJ PF13675.1 EAQ85560.1 - 0.023 15.0 1.5 0.065 13.5 1.0 1.8 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3184 PF11380.3 EAQ85560.1 - 0.024 12.5 1.0 0.029 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Prominin PF05478.6 EAQ85560.1 - 0.029 11.9 0.2 0.034 11.7 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 EAQ85560.1 - 0.033 14.5 0.1 0.062 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3987 PF13148.1 EAQ85560.1 - 0.035 12.6 0.4 0.052 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IncA PF04156.9 EAQ85560.1 - 0.038 13.5 0.7 0.058 12.9 0.5 1.3 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EAQ85560.1 - 0.049 12.5 1.7 0.071 12.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.8 EAQ85560.1 - 0.062 12.3 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Mnd1 PF03962.10 EAQ85560.1 - 0.067 12.8 3.2 0.11 12.1 2.2 1.2 1 0 0 1 1 1 0 Mnd1 family DUF607 PF04678.8 EAQ85560.1 - 0.074 12.9 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Rogdi_lz PF10259.4 EAQ85560.1 - 0.08 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DinB_2 PF12867.2 EAQ85560.1 - 0.087 13.1 0.1 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 DinB superfamily Hemagglutinin PF00509.13 EAQ85560.1 - 0.17 9.9 0.2 0.23 9.5 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin THOC7 PF05615.8 EAQ85560.1 - 0.33 11.2 5.5 0.64 10.2 3.8 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 DUF1682 PF07946.9 EAQ85560.1 - 0.34 9.7 2.6 0.5 9.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) 60KD_IMP PF02096.15 EAQ85560.1 - 0.8 9.3 5.4 1.2 8.7 3.7 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein DUF106 PF01956.11 EAQ85560.1 - 1.3 8.5 3.6 0.95 8.9 1.4 1.4 2 0 0 2 2 1 0 Integral membrane protein DUF106 YbaB_DNA_bd PF02575.11 EAQ85560.1 - 1.4 8.8 8.9 4.6 7.1 4.9 2.6 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family HisKA_3 PF07730.8 EAQ85560.1 - 2.3 8.6 6.2 0.96 9.8 0.9 2.5 2 1 0 2 2 2 0 Histidine kinase tRNA-synt_1g PF09334.6 EAQ85561.1 - 1.8e-127 425.2 0.0 2.1e-126 421.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EAQ85561.1 - 1e-05 23.8 0.0 0.055 11.4 0.0 3.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Laminin_EGF PF00053.19 EAQ85561.1 - 0.14 12.0 2.3 0.35 10.8 1.6 1.7 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) RTA1 PF04479.8 EAQ85562.1 - 3.4e-21 75.7 1.5 4.4e-21 75.4 1.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF1145 PF06611.7 EAQ85562.1 - 0.015 14.9 0.4 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Lactonase PF10282.4 EAQ85563.1 - 2.5e-77 260.2 0.2 5.2e-65 219.7 0.0 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller PQQ PF01011.16 EAQ85563.1 - 0.025 14.1 0.5 4.6 6.9 0.1 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat MoeA_N PF03453.12 EAQ85564.1 - 1.1e-30 106.0 0.2 2.1e-30 105.2 0.1 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EAQ85564.1 - 8.8e-30 103.0 0.0 1.5e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain DMRL_synthase PF00885.14 EAQ85564.1 - 0.00074 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Molybdopterin PF00384.17 EAQ85565.1 - 7.5e-66 222.6 0.0 1.1e-65 222.1 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.11 EAQ85565.1 - 4.1e-11 42.5 0.3 1.2e-10 41.0 0.2 1.9 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain DUF3505 PF12013.3 EAQ85565.1 - 3.8e-08 33.5 0.5 1e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Molydop_binding PF01568.16 EAQ85565.1 - 5.9e-05 22.8 0.0 0.00035 20.3 0.0 2.2 1 1 1 2 2 2 1 Molydopterin dinucleotide binding domain DUF3505 PF12013.3 EAQ85566.1 - 1.7e-12 47.5 0.7 3.7e-12 46.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EAQ85566.1 - 0.00026 20.5 0.0 0.00053 19.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pribosyltran PF00156.22 EAQ85568.1 - 9.1e-21 73.8 0.0 2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.18 EAQ85568.1 - 1.2e-15 57.1 4.6 2.4e-15 56.2 3.2 1.5 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.9 EAQ85568.1 - 4.9e-09 35.9 0.0 9.5e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase UPRTase PF14681.1 EAQ85568.1 - 4.6e-05 22.7 0.0 0.0001 21.5 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_23 PF13489.1 EAQ85568.1 - 0.00015 21.4 0.0 0.00072 19.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PRTase_2 PF15609.1 EAQ85568.1 - 0.0045 16.3 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase TRAPPC10 PF12584.3 EAQ85568.1 - 0.0056 16.1 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 BBE PF08031.7 EAQ85568.1 - 0.032 14.1 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Methyltransf_12 PF08242.7 EAQ85568.1 - 0.11 13.0 0.0 0.61 10.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MoCo_carrier PF12694.2 EAQ85568.1 - 0.15 11.4 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Putative molybdenum carrier GTP_cyclohydroI PF01227.17 EAQ85569.1 - 9.7e-60 200.9 1.2 1.2e-59 200.6 0.8 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EAQ85569.1 - 0.00068 19.5 0.4 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c PF02518.21 EAQ85570.1 - 4e-26 90.9 0.0 7.6e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAQ85570.1 - 2.6e-25 88.6 0.1 4.5e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EAQ85570.1 - 4.5e-19 68.2 0.0 1.2e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EAQ85570.1 - 4.3e-15 55.9 0.0 5.4e-13 49.2 0.0 2.7 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 EAQ85570.1 - 5.4e-08 32.6 0.0 2.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EAQ85570.1 - 1.8e-06 27.9 0.0 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold Gemin7 PF11095.3 EAQ85570.1 - 0.00027 20.6 0.0 0.0057 16.3 0.0 2.3 2 0 0 2 2 2 1 Gem-associated protein 7 (Gemin7) Exo_endo_phos_2 PF14529.1 EAQ85571.1 - 4.2e-21 74.7 0.0 8.1e-20 70.6 0.0 3.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Chromo PF00385.19 EAQ85571.1 - 1.3e-14 53.6 1.1 2.6e-14 52.6 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Exo_endo_phos PF03372.18 EAQ85571.1 - 5.2e-09 36.4 0.1 3e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family IncA PF04156.9 EAQ85571.1 - 0.061 12.9 2.6 0.13 11.8 1.8 1.5 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EAQ85571.1 - 0.092 11.7 2.7 0.17 10.9 1.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 EAQ85571.1 - 0.096 12.5 1.0 0.3 10.9 0.7 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EAQ85571.1 - 0.39 11.1 9.0 0.64 10.4 5.3 2.2 1 1 1 2 2 2 0 SlyX DUF883 PF05957.8 EAQ85571.1 - 0.51 10.7 6.4 0.57 10.6 0.6 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ADIP PF11559.3 EAQ85571.1 - 3.4 7.5 12.2 0.2 11.5 4.4 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Abhydrolase_4 PF08386.5 EAQ85574.1 - 1e-22 79.9 0.0 2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ85574.1 - 7.1e-13 48.6 0.0 2e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ85574.1 - 6.5e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ85574.1 - 0.006 16.3 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DsrD PF08679.6 EAQ85574.1 - 0.12 12.4 0.0 0.41 10.6 0.0 1.9 1 1 1 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Methyltransf_12 PF08242.7 EAQ85575.1 - 2.6e-18 66.3 0.0 1.1e-17 64.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.1 EAQ85575.1 - 3.6e-17 62.4 0.7 2e-16 60.0 0.3 1.9 1 1 1 2 2 2 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 EAQ85575.1 - 1e-16 61.1 0.0 2.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85575.1 - 2.8e-14 53.3 0.0 6.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ85575.1 - 7.1e-13 48.4 0.0 1.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85575.1 - 1.7e-09 38.2 0.0 4.8e-07 30.3 0.0 3.1 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85575.1 - 1.6e-06 28.4 0.0 5.4e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ85575.1 - 2.6e-06 26.7 0.1 4.4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EAQ85575.1 - 3e-05 23.5 0.0 5.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EAQ85575.1 - 9.1e-05 22.0 0.0 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EAQ85575.1 - 0.00018 21.5 0.0 0.00058 19.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain SopA_C PF13979.1 EAQ85575.1 - 0.015 14.9 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 SopA-like catalytic domain RrnaAD PF00398.15 EAQ85575.1 - 0.095 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 EAQ85575.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Dimer_Tnp_hAT PF05699.9 EAQ85576.1 - 9.3e-16 57.2 0.3 1.2e-15 56.8 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Acyl_transf_1 PF00698.16 EAQ85577.1 - 1.6e-21 76.9 1.1 4.1e-14 52.6 0.8 2.1 1 1 1 2 2 2 2 Acyl transferase domain zf-RVT PF13966.1 EAQ85578.1 - 0.0011 19.2 0.1 0.022 15.0 0.0 2.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase ketoacyl-synt PF00109.21 EAQ85579.1 - 1.2e-17 64.2 0.0 1.4e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_6 PF01341.12 EAQ85581.1 - 2.3e-89 299.7 0.5 2.6e-89 299.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 GTP_cyclohydro2 PF00925.15 EAQ85582.1 - 1.1e-34 119.0 0.1 1.3e-34 118.8 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4193 PF13834.1 EAQ85583.1 - 0.15 12.2 0.4 19 5.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4193) Ribosomal_S24e PF01282.14 EAQ85584.1 - 1.6e-35 120.7 0.1 2.4e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EAQ85584.1 - 0.013 14.9 0.7 0.015 14.7 0.5 1.2 1 0 0 1 1 1 0 RRXRR protein Zn_clus PF00172.13 EAQ85585.1 - 1.7e-08 34.2 7.4 2.3e-08 33.7 5.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 EAQ85586.1 - 4.8e-34 117.7 0.0 7.3e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EAQ85586.1 - 4.3e-17 61.4 0.0 8e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ85586.1 - 2.6e-12 46.5 0.0 6e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ85586.1 - 6.6e-09 35.4 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SHS2_Rpb7-N PF03876.12 EAQ85589.1 - 6.9e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF1604 PF07713.8 EAQ85589.1 - 0.57 10.0 0.0 0.57 10.0 0.0 3.5 3 2 2 5 5 5 0 Protein of unknown function (DUF1604) DUF4613 PF15390.1 EAQ85589.1 - 3.6 5.6 7.7 5.3 5.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Sugar_tr PF00083.19 EAQ85590.1 - 1.9e-80 270.6 17.7 1.6e-41 142.3 4.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter NmrA PF05368.8 EAQ85590.1 - 2.6e-29 102.1 0.0 3.8e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.11 EAQ85590.1 - 1.3e-28 99.7 30.1 1.3e-28 99.7 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.1 EAQ85590.1 - 5.6e-11 42.7 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding TRI12 PF06609.8 EAQ85590.1 - 7.4e-09 34.3 3.8 1.5e-08 33.2 2.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) 3Beta_HSD PF01073.14 EAQ85590.1 - 7.8e-07 28.0 0.1 1.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ85590.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EAQ85590.1 - 0.00012 21.7 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAQ85590.1 - 0.00017 21.5 0.1 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EAQ85590.1 - 0.00039 20.6 0.0 0.0008 19.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAQ85590.1 - 0.0022 17.9 0.1 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EAQ85590.1 - 0.0037 16.2 0.0 0.0074 15.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Actin PF00022.14 EAQ85591.1 - 3.6e-117 391.1 0.0 4.4e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAQ85591.1 - 0.062 11.8 0.0 0.56 8.7 0.0 2.4 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.20 EAQ85592.1 - 1.8e-62 210.8 0.0 2.3e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85592.1 - 3.7e-31 108.1 0.0 7.8e-31 107.0 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85592.1 - 0.0087 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ85592.1 - 0.024 14.3 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.16 EAQ85593.1 - 6.9e-57 191.4 0.4 3.2e-36 124.1 0.2 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EAQ85593.1 - 2.1e-09 36.5 1.0 2.9e-05 22.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EAQ85593.1 - 4.5e-07 29.3 0.1 1.3e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 EAQ85593.1 - 4.2e-06 26.1 0.3 5.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EAQ85593.1 - 4.2e-06 26.0 0.0 4.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ85593.1 - 0.0018 18.2 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EAQ85593.1 - 0.0052 15.8 0.1 0.007 15.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Miro PF08477.8 EAQ85593.1 - 0.054 13.9 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein DUF1325 PF07039.6 EAQ85594.1 - 7.4e-26 90.2 0.1 1.3e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF1777 PF08648.7 EAQ85594.1 - 0.00071 19.3 9.6 0.00071 19.3 6.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EAQ85594.1 - 0.00091 19.7 19.8 0.00091 19.7 13.7 2.7 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term LBR_tudor PF09465.5 EAQ85594.1 - 0.018 14.6 0.1 0.51 10.0 0.0 2.5 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Pribosyltran PF00156.22 EAQ85594.1 - 0.089 12.5 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain PMI_typeI PF01238.16 EAQ85595.1 - 4e-139 463.7 0.0 4.6e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EAQ85595.1 - 0.0065 16.1 0.0 2.4 7.8 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain Flocculin_t3 PF13928.1 EAQ85596.1 - 0.033 14.3 10.1 2.5 8.3 5.3 2.5 2 0 0 2 2 2 0 Flocculin type 3 repeat AMP-binding PF00501.23 EAQ85597.1 - 1.3e-47 162.1 0.5 8.8e-33 113.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ85597.1 - 3.7e-10 40.6 1.8 3.8e-10 40.5 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Endomucin PF07010.7 EAQ85599.1 - 2.5 7.3 24.4 4.1 6.6 16.9 1.4 1 1 0 1 1 1 0 Endomucin Sporozoite_P67 PF05642.6 EAQ85599.1 - 9.5 3.9 12.5 11 3.6 8.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.14 EAQ85600.1 - 9.1e-07 28.2 1.2 0.0046 16.0 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EAQ85600.1 - 0.00026 20.9 0.0 0.00058 19.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ85600.1 - 0.0019 17.1 0.6 0.0034 16.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAQ85600.1 - 0.0098 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EAQ85600.1 - 0.037 13.7 0.2 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 EAQ85600.1 - 0.044 13.6 0.1 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ85600.1 - 0.059 12.2 0.2 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EAQ85600.1 - 0.078 13.3 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ85600.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EAQ85600.1 - 0.23 10.0 0.2 0.32 9.5 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase TFIID-18kDa PF02269.11 EAQ85601.1 - 1.4e-20 72.8 1.6 3e-20 71.8 0.3 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit MULE PF10551.4 EAQ85603.1 - 1.4e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ85603.1 - 0.0029 18.0 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain 7TM_GPCR_Srj PF10319.4 EAQ85603.1 - 0.077 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj Peptidase_S8 PF00082.17 EAQ85604.1 - 1.7e-46 158.6 16.8 2.3e-46 158.2 11.7 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAQ85604.1 - 1.8e-07 31.6 0.0 4.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Leu_zip PF15294.1 EAQ85605.1 - 0.0022 17.1 3.9 0.0036 16.4 2.7 1.2 1 0 0 1 1 1 1 Leucine zipper Uds1 PF15456.1 EAQ85605.1 - 0.0088 16.0 4.9 0.0088 16.0 3.4 1.6 2 0 0 2 2 2 1 Up-regulated During Septation Shugoshin_N PF07558.6 EAQ85605.1 - 0.009 15.7 1.7 0.053 13.2 1.3 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EAQ85605.1 - 0.12 11.8 7.7 0.22 11.1 5.4 1.3 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EAQ85605.1 - 2 8.4 5.6 11 6.0 4.0 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 EAQ85605.1 - 2.9 8.2 4.7 10 6.5 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3552 PF12072.3 EAQ85605.1 - 4.3 6.4 11.7 8 5.6 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Peptidase_M20 PF01546.23 EAQ85606.1 - 9.6e-34 116.5 0.0 1.3e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAQ85606.1 - 2.6e-13 49.6 0.0 4.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1967 PF09269.6 EAQ85606.1 - 0.16 11.6 0.1 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Yippee-Mis18 PF03226.9 EAQ85607.1 - 3.2e-16 59.1 0.0 1e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-dskA_traR PF01258.12 EAQ85607.1 - 0.053 13.2 0.8 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger ODC_AZ PF02100.12 EAQ85608.1 - 4e-28 97.0 0.0 5.6e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme MAGE_N PF12440.3 EAQ85608.1 - 0.028 14.6 0.2 1.4 9.2 1.9 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal His_biosynth PF00977.16 EAQ85609.1 - 1e-48 165.6 0.6 4e-48 163.6 0.4 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EAQ85609.1 - 5.9e-28 97.6 0.0 9.3e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EAQ85609.1 - 2.6e-07 30.4 0.0 3.6e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EAQ85609.1 - 4.4e-06 26.3 0.0 1.5e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 EAQ85609.1 - 0.014 14.2 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 EAQ85609.1 - 0.074 12.4 0.0 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 TFIIIC_sub6 PF10419.4 EAQ85610.1 - 2.7e-13 49.1 0.0 4.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit S4_2 PF13275.1 EAQ85610.1 - 0.23 11.0 1.0 0.48 10.0 0.7 1.4 1 0 0 1 1 1 0 S4 domain DUF946 PF06101.6 EAQ85611.1 - 0.0012 16.9 0.0 0.0022 16.1 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Dimer_Tnp_hAT PF05699.9 EAQ85612.1 - 2.7e-15 55.7 0.1 4.7e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.22 EAQ85613.1 - 3.3e-33 114.8 0.0 6.9e-33 113.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIAV_Rev PF11129.3 EAQ85613.1 - 0.043 13.7 0.4 0.54 10.2 0.1 2.5 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus Glyco_hydro_11 PF00457.12 EAQ85617.1 - 1.5e-48 164.6 3.7 2.5e-48 163.8 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EAQ85617.1 - 1.1e-11 44.2 19.8 2.9e-11 42.8 13.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_3 PF01494.14 EAQ85618.1 - 1.5e-07 30.8 0.0 4e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Tyrosinase PF00264.15 EAQ85621.1 - 1.2e-21 77.9 0.0 1.5e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M16 PF00675.15 EAQ85622.1 - 1.4e-15 57.3 0.0 2.5e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAQ85622.1 - 1.1e-11 44.7 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain FAD_binding_9 PF08021.6 EAQ85624.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PEP-utilizers_C PF02896.13 EAQ85626.1 - 9.1e-53 179.0 0.0 1.2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 EAQ85626.1 - 1.9e-52 178.3 0.2 3.6e-52 177.4 0.2 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Ldh_1_N PF00056.18 EAQ85627.1 - 1.7e-28 99.2 0.7 2e-28 98.9 0.5 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Malic_M PF03949.10 EAQ85627.1 - 0.0035 16.9 0.1 0.0074 15.8 0.1 1.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Glyco_hydro_4 PF02056.11 EAQ85627.1 - 0.021 14.1 0.1 0.046 13.0 0.0 1.6 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TIM-br_sig_trns PF09370.5 EAQ85627.1 - 0.024 13.7 0.1 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 TIM-barrel signal transduction protein OstA_2 PF13100.1 EAQ85627.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 OstA-like protein ThiF PF00899.16 EAQ85627.1 - 0.11 12.2 2.6 0.17 11.7 1.8 1.6 1 1 0 1 1 1 0 ThiF family TrkA_N PF02254.13 EAQ85627.1 - 0.12 12.3 1.7 0.19 11.7 1.2 1.5 1 1 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EAQ85627.1 - 0.14 11.6 1.7 0.29 10.5 1.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EAQ85627.1 - 0.15 11.4 4.7 0.7 9.2 3.3 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EAQ85627.1 - 0.22 11.9 2.9 0.69 10.3 0.7 2.5 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Exo_endo_phos_2 PF14529.1 EAQ85628.1 - 1.4e-22 79.4 0.0 2.1e-21 75.7 0.0 2.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EAQ85628.1 - 1.8e-15 56.8 0.0 5e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EAQ85628.1 - 1.4e-10 41.5 0.2 6.5e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family APG6 PF04111.7 EAQ85628.1 - 0.08 11.9 1.3 0.15 11.0 0.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EAQ85628.1 - 0.098 11.0 0.4 0.19 10.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF948 PF06103.6 EAQ85628.1 - 0.17 11.7 2.3 0.29 11.0 0.7 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EAQ85628.1 - 0.3 10.6 4.8 0.65 9.5 3.3 1.5 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EAQ85628.1 - 0.51 10.7 9.4 0.74 10.2 5.4 2.1 1 1 1 2 2 2 0 SlyX ADIP PF11559.3 EAQ85628.1 - 4.6 7.1 12.5 0.2 11.5 4.4 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3439 PF11921.3 EAQ85629.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA PF00004.24 EAQ85630.1 - 0.13 12.5 0.1 1.3 9.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RXT2_N PF08595.6 EAQ85630.1 - 0.81 9.4 4.8 9.6 6.0 0.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal RVT_1 PF00078.22 EAQ85633.1 - 1.7e-12 47.1 0.0 5.1e-06 25.9 0.1 3.1 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) EIAV_Rev PF11129.3 EAQ85633.1 - 0.058 13.3 0.7 0.49 10.3 0.1 2.4 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus Pkinase PF00069.20 EAQ85634.1 - 3.5e-23 82.0 0.0 1e-10 41.2 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85634.1 - 7.8e-07 28.4 0.0 0.0096 15.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EAQ85634.1 - 4.6e-05 23.2 2.4 0.00021 21.0 0.2 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family FAD_binding_3 PF01494.14 EAQ85635.1 - 7.1e-12 45.0 0.0 1.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DUF2457 PF10446.4 EAQ85637.1 - 2.4 6.7 11.3 3.4 6.2 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sugar_tr PF00083.19 EAQ85638.1 - 2e-66 224.4 22.2 2.1e-64 217.7 11.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85638.1 - 6.4e-17 61.3 19.4 6.4e-17 61.3 13.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ85638.1 - 0.0016 16.9 2.5 0.0016 16.9 1.8 2.5 2 0 0 2 2 2 1 MFS/sugar transport protein Chromo PF00385.19 EAQ85639.1 - 2e-06 27.3 2.0 3.8e-06 26.4 0.6 2.0 1 1 1 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain NDUF_B7 PF05676.8 EAQ85641.1 - 3.8e-32 109.5 4.8 4.5e-32 109.2 3.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EAQ85641.1 - 0.0018 17.9 3.6 0.0019 17.9 2.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_61 PF03443.9 EAQ85642.1 - 3.3e-42 144.7 0.0 3.8e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1996 PF09362.5 EAQ85644.1 - 7e-86 287.7 1.0 8.4e-86 287.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Abhydrolase_4 PF08386.5 EAQ85645.1 - 2.5e-20 72.2 0.0 4.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ85645.1 - 7.2e-12 45.3 0.0 4.2e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ85645.1 - 1.2e-08 35.1 0.1 5.8e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ85645.1 - 0.035 13.8 0.0 0.2 11.3 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EAQ85646.1 - 3.3e-06 26.4 0.0 6.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85646.1 - 0.0022 17.1 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Dimer_Tnp_hAT PF05699.9 EAQ85647.1 - 1.7e-11 43.5 0.0 5e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CENP-F_leu_zip PF10473.4 EAQ85647.1 - 0.04 13.7 6.2 1 9.2 2.0 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EAQ85647.1 - 0.07 11.5 7.7 0.18 10.2 5.4 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light EamA PF00892.15 EAQ85648.1 - 9.8e-12 45.0 32.6 1.2e-06 28.6 11.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAQ85648.1 - 5e-07 29.9 1.1 5e-07 29.9 0.8 2.7 3 0 0 3 3 3 2 Multidrug resistance efflux transporter DUF202 PF02656.10 EAQ85648.1 - 0.17 12.0 9.7 0.18 12.0 0.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) TPT PF03151.11 EAQ85648.1 - 0.45 10.1 28.4 0.2 11.3 11.8 2.8 3 1 0 3 3 3 0 Triose-phosphate Transporter family PRRSV_Env PF02340.10 EAQ85648.1 - 3.1 6.8 11.5 9.8 5.2 0.1 3.1 2 1 1 3 3 3 0 PRRSV putative envelope protein Ank PF00023.25 EAQ85649.1 - 1e-14 53.4 0.5 3.6e-06 26.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EAQ85649.1 - 6.2e-12 45.6 0.1 9.5e-05 22.6 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ85649.1 - 2.8e-11 43.5 0.1 5.6e-05 23.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ85649.1 - 1e-10 41.5 0.4 2.4e-05 24.3 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85649.1 - 5.6e-07 29.1 0.3 0.072 13.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EAQ85649.1 - 5.9e-07 29.1 0.2 4.1e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain MbeD_MobD PF04899.7 EAQ85649.1 - 0.022 14.6 2.5 0.052 13.4 1.2 2.1 1 1 0 1 1 1 0 MbeD/MobD like AAA_13 PF13166.1 EAQ85649.1 - 0.6 8.5 5.9 0.85 8.0 4.1 1.2 1 0 0 1 1 1 0 AAA domain Pal1 PF08316.6 EAQ85653.1 - 5.8 7.3 11.9 2 8.8 5.3 2.4 3 0 0 3 3 3 0 Pal1 cell morphology protein Aldo_ket_red PF00248.16 EAQ85656.1 - 2.3e-37 128.3 0.0 2.7e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_12 PF13424.1 EAQ85657.1 - 3.6e-12 46.0 0.1 0.00037 20.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EAQ85657.1 - 1.3e-10 40.6 0.2 7.4e-10 38.1 0.1 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 EAQ85657.1 - 4.3e-07 29.0 0.0 1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EAQ85657.1 - 6e-07 29.9 2.8 0.0077 16.8 2.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ85657.1 - 8.9e-07 29.0 6.5 1.3 9.8 0.4 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ85657.1 - 1.1e-05 25.6 2.9 0.035 14.4 0.9 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ85657.1 - 3.4e-05 23.6 4.4 8.1 6.5 0.2 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ85657.1 - 0.00036 20.2 0.2 0.78 9.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ85657.1 - 0.00053 20.0 0.0 2.9 8.0 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.7 EAQ85657.1 - 0.0043 16.7 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 EAQ85657.1 - 0.019 14.7 0.5 23 5.0 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ85657.1 - 0.044 14.2 1.9 64 4.3 0.5 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_25 PF13481.1 EAQ85657.1 - 0.046 13.1 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.1 EAQ85657.1 - 0.09 12.5 0.1 7.8 6.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Peroxin-13_N PF04088.8 EAQ85658.1 - 0.039 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region HeLo PF14479.1 EAQ85659.1 - 3.2e-43 147.9 0.0 7.5e-43 146.7 0.0 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation Aa_trans PF01490.13 EAQ85661.1 - 2.4e-44 151.4 34.3 2.9e-44 151.1 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Esterase_phd PF10503.4 EAQ85662.1 - 8.5e-24 84.0 1.4 1.1e-23 83.6 1.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EAQ85662.1 - 1.2e-11 44.3 0.3 1.7e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ85662.1 - 1.7e-06 27.8 0.2 2.5e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ85662.1 - 0.0024 17.4 0.1 0.0034 16.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EAQ85662.1 - 0.017 13.8 0.1 0.024 13.3 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_6 PF12697.2 EAQ85662.1 - 0.044 13.6 0.1 0.097 12.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EAQ85662.1 - 0.047 13.1 0.3 0.075 12.4 0.1 1.5 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.11 EAQ85663.1 - 3.5e-05 23.3 0.0 6.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAQ85663.1 - 0.005 16.5 0.1 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EAQ85663.1 - 0.01 15.3 0.2 0.17 11.2 0.1 2.3 1 1 0 1 1 1 0 Putative esterase TOM20_plant PF06552.7 EAQ85665.1 - 0.076 12.5 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Sugar_tr PF00083.19 EAQ85666.1 - 4.8e-94 315.4 22.9 3.6e-65 220.3 7.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ85666.1 - 4.5e-17 61.8 27.4 5.1e-09 35.3 3.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ85666.1 - 0.0027 16.1 7.0 0.0027 16.1 4.8 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein Serglycin PF04360.7 EAQ85666.1 - 0.022 14.4 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Serglycin Peptidase_M43 PF05572.8 EAQ85667.1 - 2.5e-06 27.1 0.1 5.7e-06 26.0 0.0 1.6 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A polyprenyl_synt PF00348.12 EAQ85668.1 - 2.7e-34 118.1 0.0 4.9e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EAQ85668.1 - 0.00073 18.8 0.2 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Dioxygenase_C PF00775.16 EAQ85669.1 - 1.6e-08 34.0 0.1 2.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase PAN_1 PF00024.21 EAQ85670.1 - 1.9e-10 40.3 16.8 0.00061 19.4 0.7 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 EAQ85670.1 - 1.7e-05 24.4 16.4 0.0085 15.7 0.2 4.0 4 0 0 4 4 4 2 PAN domain PAN_3 PF08277.7 EAQ85670.1 - 0.0038 16.8 2.5 6 6.5 0.1 3.5 3 0 0 3 3 3 3 PAN-like domain Rhodanese PF00581.15 EAQ85672.1 - 2.4e-07 31.0 0.0 4.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Hexapep PF00132.19 EAQ85674.1 - 5.5e-09 35.1 6.1 5.4e-05 22.5 0.5 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAQ85674.1 - 3.4e-05 23.3 3.5 0.017 14.6 0.1 3.3 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Epimerase PF01370.16 EAQ85675.1 - 8.6e-08 31.9 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ85675.1 - 1.4e-05 25.2 2.8 5.5e-05 23.2 1.9 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ85675.1 - 0.00078 18.2 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EAQ85675.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAQ85675.1 - 0.043 13.7 0.9 0.11 12.4 0.7 1.7 1 1 0 1 1 1 0 short chain dehydrogenase 2OG-FeII_Oxy_2 PF13532.1 EAQ85679.1 - 1.3e-18 67.5 0.0 4.7e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAQ85679.1 - 4.8e-10 39.6 0.1 1.5e-07 31.6 0.0 2.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pex14_N PF04695.8 EAQ85679.1 - 0.037 14.0 5.6 0.071 13.1 3.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2OG-FeII_Oxy_3 PF13640.1 EAQ85679.1 - 0.066 13.7 0.2 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF2360 PF10152.4 EAQ85679.1 - 0.086 13.1 3.4 0.13 12.5 2.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Suf PF05843.9 EAQ85679.1 - 4.5 6.9 6.3 8.4 6.0 3.0 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 EAQ85680.1 - 0.0081 15.3 0.0 0.077 12.1 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain NAS PF03059.11 EAQ85681.1 - 3.9e-66 223.0 0.2 4.8e-35 121.0 0.0 2.0 1 1 1 2 2 2 2 Nicotianamine synthase protein Methyltransf_18 PF12847.2 EAQ85681.1 - 0.0022 18.5 0.1 0.0087 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85681.1 - 0.11 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATP-grasp_4 PF13535.1 EAQ85682.1 - 5.7e-19 68.5 0.1 1.2e-16 61.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAQ85682.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus POTRA_1 PF08478.5 EAQ85682.1 - 0.2 11.7 0.0 0.62 10.1 0.0 1.7 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Lipocalin_2 PF08212.7 EAQ85684.1 - 4e-16 59.0 0.0 5.2e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 EAQ85684.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.4 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family RE_NgoBV PF09564.5 EAQ85684.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 NgoBV restriction endonuclease VSP PF03302.8 EAQ85685.1 - 0.002 16.8 0.3 0.0025 16.5 0.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4448 PF14610.1 EAQ85685.1 - 0.0053 16.2 0.0 0.28 10.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4448) SKG6 PF08693.5 EAQ85685.1 - 0.012 14.8 2.0 0.031 13.6 0.2 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Peptidase_M57 PF12388.3 EAQ85686.1 - 0.24 10.6 1.5 4.6 6.5 0.1 2.1 1 1 0 2 2 2 0 Dual-action HEIGH metallo-peptidase 4HBT_2 PF13279.1 EAQ85688.1 - 0.002 18.5 0.0 0.0031 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3455 PF11937.3 EAQ85691.1 - 4.7e-11 42.9 0.0 7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) C2 PF00168.25 EAQ85692.1 - 5.1e-13 48.6 0.1 9.6e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3668 PF12416.3 EAQ85692.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Cep120 protein Glyco_hydro_47 PF01532.15 EAQ85693.1 - 8.6e-151 502.6 0.0 9.8e-151 502.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EAQ85693.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) UPF0546 PF10639.4 EAQ85694.1 - 1.2e-29 102.4 0.3 4.1e-29 100.6 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 PetM PF08041.6 EAQ85694.1 - 0.15 11.5 1.0 0.34 10.4 0.7 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 DUF2011 PF09428.5 EAQ85695.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DUF1311 PF07007.7 EAQ85695.1 - 5.2 7.2 10.6 2.2 8.3 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) Proteasome PF00227.21 EAQ85697.1 - 9.1e-48 162.0 0.0 1.4e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAQ85697.1 - 1.9e-13 49.4 0.1 1.9e-13 49.4 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF550 PF04447.7 EAQ85697.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF550) DUF3650 PF12368.3 EAQ85697.1 - 0.36 10.3 6.0 0.081 12.4 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 EAQ85698.1 - 1.7e-23 81.9 0.8 1.7e-22 78.7 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) SIS PF01380.17 EAQ85699.1 - 6.6e-11 41.9 0.4 4.7e-10 39.1 0.3 2.1 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EAQ85699.1 - 7.8e-05 22.4 0.0 0.00026 20.7 0.0 1.7 1 1 1 2 2 2 1 SIS domain LMWPc PF01451.16 EAQ85700.1 - 1.9e-33 115.6 0.0 2.9e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.20 EAQ85701.1 - 2.7e-72 243.0 0.0 3.3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85701.1 - 3.3e-31 108.2 0.0 4.7e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ85701.1 - 0.013 15.2 0.1 0.065 12.9 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EAQ85701.1 - 0.078 12.0 0.0 0.21 10.6 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UTP15_C PF09384.5 EAQ85702.1 - 9.6e-49 164.8 0.0 1.4e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EAQ85702.1 - 4.2e-27 93.0 2.8 1.2e-08 34.5 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EAQ85702.1 - 1 9.7 4.8 43 4.5 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain zf-MIZ PF02891.15 EAQ85703.1 - 4.1e-08 32.5 8.6 9.3e-06 25.0 6.0 2.6 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger DUF3675 PF12428.3 EAQ85703.1 - 1.3 9.3 3.0 2.9 8.1 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF3464 PF11947.3 EAQ85703.1 - 4 6.8 7.8 10 5.5 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Kei1 PF08552.6 EAQ85703.1 - 4.9 6.7 4.4 9.2 5.8 3.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_S30 PF04758.9 EAQ85704.1 - 0.026 14.2 0.0 0.026 14.2 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S30 RRM_6 PF14259.1 EAQ85704.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3832 PF12909.2 EAQ85707.1 - 0.053 13.5 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3832) MULE PF10551.4 EAQ85708.1 - 9.7e-19 67.3 0.0 2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ85708.1 - 0.00085 17.9 0.0 0.00085 17.9 0.0 1.8 2 0 0 2 2 2 1 Transposase, Mutator family CDK5_activator PF03261.10 EAQ85708.1 - 4.7 6.4 10.7 8.2 5.6 7.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein MULE PF10551.4 EAQ85710.1 - 3.7e-20 71.8 0.2 4.1e-17 62.1 0.0 2.8 2 0 0 2 2 2 2 MULE transposase domain Transposase_mut PF00872.13 EAQ85710.1 - 1.7e-09 36.7 1.1 8.2e-06 24.6 0.0 2.4 2 0 0 2 2 2 2 Transposase, Mutator family MULE PF10551.4 EAQ85711.1 - 4e-14 52.5 0.0 9.3e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ85711.1 - 4.5e-07 28.7 0.0 7.1e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Arrestin_N PF00339.24 EAQ85714.1 - 3e-16 59.5 0.0 8.5e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain RrnaAD PF00398.15 EAQ85715.1 - 9.7e-41 139.5 0.0 1.4e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EAQ85715.1 - 1.3e-09 38.0 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ85715.1 - 0.00096 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EAQ85715.1 - 0.023 15.2 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EAQ85715.1 - 0.03 13.9 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 EAQ85715.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CMAS PF02353.15 EAQ85715.1 - 0.05 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase BNIP2 PF12496.3 EAQ85715.1 - 0.075 13.2 3.2 0.091 12.9 2.2 1.4 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 NPV_P10 PF05531.7 EAQ85716.1 - 0.11 12.7 3.2 0.37 11.0 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MSP1_C PF07462.6 EAQ85716.1 - 1.2 7.4 0.9 2.6 6.3 0.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2968 PF11180.3 EAQ85716.1 - 2.4 7.4 7.7 0.076 12.3 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) NACHT PF05729.7 EAQ85718.1 - 8.9e-16 57.9 0.0 2e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AFG1_ATPase PF03969.11 EAQ85718.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.1 EAQ85718.1 - 0.0072 16.3 0.5 0.029 14.3 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain PIF1 PF05970.9 EAQ85718.1 - 0.01 14.8 0.1 0.025 13.5 0.1 1.7 1 1 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.1 EAQ85718.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L16 PF00252.13 EAQ85719.1 - 2.5e-31 108.1 0.0 3.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 EAQ85720.1 - 2.7e-24 84.4 0.0 3.1e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SPX PF03105.14 EAQ85721.1 - 0.14 11.9 13.7 0.039 13.7 6.5 2.1 2 1 1 3 3 3 0 SPX domain CALCOCO1 PF07888.6 EAQ85721.1 - 0.16 10.2 18.7 0.24 9.6 12.9 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Herpes_UL6 PF01763.11 EAQ85721.1 - 0.3 9.1 7.0 0.57 8.3 4.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Tweety PF04906.8 EAQ85721.1 - 0.4 9.0 2.5 0.58 8.5 1.7 1.2 1 0 0 1 1 1 0 Tweety LMBR1 PF04791.11 EAQ85721.1 - 0.69 8.4 7.3 0.93 7.9 5.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Z1 PF10593.4 EAQ85721.1 - 1.9 7.6 7.5 2.3 7.3 4.7 1.5 1 1 0 1 1 1 0 Z1 domain V_ATPase_I PF01496.14 EAQ85721.1 - 2 6.1 9.9 3.7 5.2 6.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EAQ85721.1 - 5.3 7.1 13.3 1.8 8.6 5.2 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Acetyltransf_2 PF00797.12 EAQ85722.1 - 1.3e-35 123.0 0.0 3.2e-35 121.8 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Vac7 PF12751.2 EAQ85723.1 - 1.5e-110 369.7 25.8 2.4e-99 332.8 3.3 2.8 2 1 1 3 3 3 2 Vacuolar segregation subunit 7 FA_desaturase PF00487.19 EAQ85724.1 - 4.9e-30 104.8 17.8 6.6e-30 104.4 12.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EAQ85724.1 - 1.4e-19 69.0 0.1 2.5e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Aldo_ket_red PF00248.16 EAQ85725.1 - 1.4e-69 234.0 0.1 1.6e-69 233.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1498 PF07385.7 EAQ85725.1 - 0.083 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) zf-CCHC PF00098.18 EAQ85726.1 - 1.4e-46 154.3 76.5 8.9e-08 31.7 1.8 10.3 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_3 PF13917.1 EAQ85726.1 - 2.4e-06 27.1 53.0 0.018 14.7 0.4 8.9 3 3 6 9 9 9 5 Zinc knuckle zf-CCHC_2 PF13696.1 EAQ85726.1 - 8.2e-05 22.0 50.2 0.014 14.8 0.3 9.8 4 3 5 9 9 9 5 Zinc knuckle zf-CCHC_4 PF14392.1 EAQ85726.1 - 0.00012 21.6 54.7 0.15 11.7 0.9 9.1 9 0 0 9 9 9 6 Zinc knuckle zf-CCHC_6 PF15288.1 EAQ85726.1 - 0.0068 16.0 59.6 0.013 15.1 0.3 8.2 6 2 3 9 9 9 5 Zinc knuckle Methyltransf_23 PF13489.1 EAQ85727.1 - 1.4e-14 54.1 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85727.1 - 2.8e-08 34.1 0.0 3.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ85727.1 - 7.7e-06 26.3 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ85727.1 - 0.00042 20.3 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85727.1 - 0.00048 20.6 0.0 0.00076 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85727.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ85727.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DDE_1 PF03184.14 EAQ85728.1 - 3.8e-24 85.0 0.0 6.3e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ85728.1 - 1.5e-15 56.7 0.0 3.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ85728.1 - 4e-07 29.4 0.0 8.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ85728.1 - 2.2e-05 24.2 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EAQ85728.1 - 0.0079 15.8 0.0 0.025 14.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DnaJ PF00226.26 EAQ85730.1 - 1.6e-25 88.5 3.8 2.6e-25 87.9 2.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EAQ85730.1 - 8.7e-15 54.5 16.6 1.4e-14 53.8 11.5 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EAQ85730.1 - 1.8e-14 53.4 0.0 7.9e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EAQ85730.1 - 0.7 9.5 9.3 4.2 7.0 0.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DHHA1 PF02272.14 EAQ85730.1 - 3.2 7.5 4.7 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 DHHA1 domain DUF2910 PF11139.3 EAQ85731.1 - 0.32 10.0 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) CopD PF05425.8 EAQ85731.1 - 0.51 10.5 1.7 4.3 7.6 0.0 2.9 2 1 2 4 4 4 0 Copper resistance protein D Ribosomal_60s PF00428.14 EAQ85732.1 - 1.2e-26 92.9 11.4 1.4e-26 92.6 7.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Jun PF03957.8 EAQ85732.1 - 0.044 13.5 0.4 0.046 13.4 0.3 1.0 1 0 0 1 1 1 0 Jun-like transcription factor DUF2408 PF10303.4 EAQ85733.1 - 3e-48 163.3 8.1 1.4e-31 109.4 0.3 4.7 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Cob_adeno_trans PF01923.13 EAQ85733.1 - 0.031 14.0 4.0 0.1 12.3 0.3 3.0 2 1 0 3 3 3 0 Cobalamin adenosyltransferase HR1 PF02185.11 EAQ85733.1 - 0.69 9.6 4.6 1.5 8.6 0.5 2.8 1 1 1 2 2 2 0 Hr1 repeat Laminin_II PF06009.7 EAQ85733.1 - 1.5 8.6 5.8 0.25 11.0 0.4 2.4 3 0 0 3 3 3 0 Laminin Domain II Spc24 PF08286.6 EAQ85733.1 - 1.8 8.2 6.9 0.34 10.6 0.4 3.1 2 1 2 4 4 4 0 Spc24 subunit of Ndc80 Myb_CC_LHEQLE PF14379.1 EAQ85733.1 - 2.8 7.6 6.2 14 5.3 0.2 3.3 3 0 0 3 3 3 0 MYB-CC type transfactor, LHEQLE motif DUF1664 PF07889.7 EAQ85733.1 - 3.6 7.3 6.8 0.65 9.7 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EAQ85733.1 - 5.3 7.4 6.5 1.7 9.0 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) YCII PF03795.9 EAQ85734.1 - 5.6e-09 36.0 0.0 6.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UBA PF00627.26 EAQ85735.1 - 0.0002 21.0 0.2 0.00064 19.4 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain DUF2421 PF10334.4 EAQ85735.1 - 0.0039 16.8 0.1 0.0039 16.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) NOZZLE PF08744.5 EAQ85735.1 - 0.024 14.0 1.6 0.034 13.5 1.1 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE UBX PF00789.15 EAQ85735.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 UBX domain DUF572 PF04502.8 EAQ85735.1 - 0.19 10.9 21.4 0.23 10.6 14.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOBP PF15279.1 EAQ85735.1 - 0.71 10.2 7.0 1 9.6 4.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Hom_end_hint PF05203.11 EAQ85735.1 - 0.73 9.5 6.8 1.4 8.5 4.7 1.5 1 0 0 1 1 1 0 Hom_end-associated Hint Ndc1_Nup PF09531.5 EAQ85735.1 - 1 7.7 7.5 1.2 7.4 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_env PF01673.13 EAQ85735.1 - 2.1 6.8 6.9 2.6 6.4 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Complex1_LYR_2 PF13233.1 EAQ85735.1 - 3.2 8.2 9.1 5.7 7.4 6.2 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Ycf1 PF05758.7 EAQ85735.1 - 5.1 4.6 14.2 5.9 4.4 9.8 1.1 1 0 0 1 1 1 0 Ycf1 Motile_Sperm PF00635.21 EAQ85736.1 - 2.3e-10 40.1 0.1 4.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain zf-CCHC_6 PF15288.1 EAQ85736.1 - 2.4e-05 23.8 0.9 6.9e-05 22.4 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle MULE PF10551.4 EAQ85736.1 - 0.06 13.5 0.1 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 MULE transposase domain DUF3440 PF11922.3 EAQ85736.1 - 0.089 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) DUF3275 PF11679.3 EAQ85736.1 - 4.9 6.7 6.7 2.1 7.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) AMP-binding PF00501.23 EAQ85737.1 - 3.4e-67 226.6 3.3 1.8e-43 148.4 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ85737.1 - 1.1e-16 61.4 0.3 2.5e-16 60.3 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EAQ85737.1 - 0.0011 17.6 0.0 0.017 13.6 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter OB_NTP_bind PF07717.11 EAQ85738.1 - 1.1e-22 80.0 0.0 2.4e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAQ85738.1 - 8.4e-22 77.1 0.0 8.4e-22 77.1 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAQ85738.1 - 9.3e-12 44.6 0.0 2.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ85738.1 - 1.5e-05 24.5 0.1 3.7e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAQ85738.1 - 0.00015 21.9 0.0 0.00038 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EAQ85738.1 - 0.0061 15.4 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EAQ85738.1 - 0.0083 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain cobW PF02492.14 EAQ85738.1 - 0.041 13.3 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EAQ85738.1 - 3.4 7.9 0.0 3.4 7.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain G-patch PF01585.18 EAQ85739.1 - 4e-11 42.5 0.6 1.1e-10 41.0 0.4 1.8 1 0 0 1 1 1 1 G-patch domain DUF4106 PF13388.1 EAQ85739.1 - 9.4 5.0 9.4 15 4.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Ecm33 PF12454.3 EAQ85740.1 - 3.4e-14 52.4 2.4 3.4e-14 52.4 1.6 2.9 4 0 0 4 4 4 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EAQ85740.1 - 8.9e-10 38.5 0.1 0.0021 17.9 0.0 3.9 2 1 1 3 3 3 2 Receptor L domain LRR_9 PF14580.1 EAQ85740.1 - 0.072 12.6 0.6 0.14 11.6 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeat HhH-GPD PF00730.20 EAQ85741.1 - 1.9e-15 57.0 0.0 4.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.9 EAQ85742.1 - 1.7e-111 371.7 0.0 2e-111 371.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.11 EAQ85743.1 - 2.1e-43 146.3 0.2 2.4e-43 146.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MIR PF02815.14 EAQ85743.1 - 0.029 13.9 0.0 0.034 13.6 0.0 1.0 1 0 0 1 1 1 0 MIR domain Mito_carr PF00153.22 EAQ85744.1 - 1.9e-30 104.4 0.8 7.6e-23 80.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Gemini_C4 PF01492.12 EAQ85745.1 - 0.039 13.6 0.3 0.042 13.5 0.2 1.1 1 0 0 1 1 1 0 Geminivirus C4 protein vMSA PF00695.14 EAQ85746.1 - 0.15 11.2 0.8 0.16 11.1 0.6 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus CI-B14_5a PF07347.7 EAQ85747.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) adh_short PF00106.20 EAQ85748.1 - 1.3e-30 106.5 1.6 1.7e-30 106.1 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ85748.1 - 1.3e-21 77.4 0.6 7e-21 75.0 0.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ85748.1 - 1.2e-15 57.6 0.1 1.6e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ85748.1 - 5.5e-07 29.2 0.2 2.2e-06 27.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acetyltransf_1 PF00583.19 EAQ85749.1 - 0.00022 21.1 0.1 0.0018 18.2 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAQ85749.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF4646 PF15496.1 EAQ85750.1 - 1.5e-06 28.2 0.2 2.5e-05 24.2 0.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) rRNA_processing PF08524.6 EAQ85750.1 - 0.0015 18.3 8.2 0.0015 18.3 5.7 1.6 2 0 0 2 2 2 1 rRNA processing IF-2B PF01008.12 EAQ85751.1 - 1.2e-37 129.4 0.0 3.1e-37 128.1 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Cep57_MT_bd PF06657.8 EAQ85751.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Ribosomal_L7Ae PF01248.21 EAQ85752.1 - 4.5e-15 54.9 0.4 5.8e-14 51.3 0.3 2.5 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynactin_p62 PF05502.8 EAQ85752.1 - 0.12 11.0 4.4 0.17 10.6 3.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family Moulting_cycle PF04870.11 EAQ85752.1 - 0.39 9.7 8.1 0.57 9.2 5.6 1.2 1 0 0 1 1 1 0 Moulting cycle Tom37_C PF11801.3 EAQ85752.1 - 8.8 6.1 7.7 17 5.2 5.3 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1761 PF08570.5 EAQ85753.1 - 8.9e-23 80.6 3.9 1e-22 80.4 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.13 EAQ85754.1 - 1.4e-50 171.0 0.0 2.1e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Band_7 PF01145.20 EAQ85755.1 - 5.6e-24 85.0 5.1 7.6e-24 84.5 3.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EAQ85755.1 - 0.011 15.1 2.2 0.013 14.9 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) RNase_T PF00929.19 EAQ85756.1 - 2e-08 34.6 0.0 2.2e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Exonuclease Glyco_transf_8 PF01501.15 EAQ85757.1 - 8.5e-27 94.0 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EAQ85757.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.6 1 1 0 1 1 1 0 Mannosyltransferase putative UCH PF00443.24 EAQ85758.1 - 5.6e-35 120.7 0.0 3.2e-34 118.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ85758.1 - 9.2e-17 61.4 0.0 1.7e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.5 EAQ85759.1 - 2.8e-30 104.8 1.1 1.9e-29 102.1 0.0 2.9 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Shugoshin_N PF07558.6 EAQ85759.1 - 0.0032 17.1 0.3 0.017 14.8 0.3 2.1 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.16 EAQ85759.1 - 0.068 13.1 0.5 0.068 13.1 0.3 3.1 2 1 0 2 2 2 0 bZIP transcription factor Reo_sigmaC PF04582.7 EAQ85759.1 - 0.35 10.0 0.5 0.56 9.3 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EAQ85759.1 - 2.3 8.6 5.7 3.1 8.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) zf-CCHC PF00098.18 EAQ85760.1 - 4.8e-47 155.7 56.3 8.1e-09 34.9 2.4 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EAQ85760.1 - 7.8e-11 41.4 36.3 0.015 14.9 0.6 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 EAQ85760.1 - 2.1e-07 30.5 36.7 0.17 11.6 0.6 6.2 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EAQ85760.1 - 0.00083 18.9 42.7 0.044 13.4 1.1 6.2 5 1 1 6 6 6 4 Zinc knuckle DUF2256 PF10013.4 EAQ85760.1 - 0.58 9.9 6.1 19 5.1 0.1 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) RMF PF04957.7 EAQ85760.1 - 0.78 9.4 15.3 1.4 8.6 0.2 3.6 3 1 1 4 4 4 0 Ribosome modulation factor Acyl-CoA_dh_1 PF00441.19 EAQ85761.1 - 7.3e-35 120.2 1.3 1.1e-34 119.7 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EAQ85761.1 - 1e-18 66.8 0.3 2.5e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EAQ85761.1 - 1.6e-16 59.5 0.7 4.1e-16 58.2 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EAQ85761.1 - 1.1e-06 29.1 0.1 7.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAQ85761.1 - 0.0012 19.0 0.2 0.0024 18.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.19 EAQ85762.1 - 2e-37 129.3 1.2 4.9e-30 104.9 0.0 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ85762.1 - 1.4e-15 57.0 0.0 3.2e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAQ85762.1 - 6e-06 26.1 0.2 0.0024 17.6 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EAQ85762.1 - 8.3e-06 24.9 0.0 0.00069 18.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ85762.1 - 9.3e-06 25.8 0.1 0.00081 19.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ85762.1 - 2.9e-05 24.3 0.2 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ85762.1 - 9.4e-05 21.0 0.1 0.0022 16.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EAQ85762.1 - 0.0002 20.5 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EAQ85762.1 - 0.0003 20.7 0.0 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ85762.1 - 0.00047 19.3 0.1 0.00075 18.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EAQ85762.1 - 0.00076 18.4 0.1 0.0014 17.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EAQ85762.1 - 0.009 15.6 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EAQ85762.1 - 0.0098 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rossmann-like PF10727.4 EAQ85762.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain ATG2_CAD PF13329.1 EAQ85763.1 - 8.9e-47 158.5 0.1 2.1e-46 157.3 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EAQ85763.1 - 4.5e-30 103.6 0.6 2.4e-29 101.3 0.1 2.5 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 EAQ85763.1 - 0.17 11.4 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Ribonuc_red_lgC PF02867.10 EAQ85763.1 - 1.6 7.1 0.0 2.6 6.4 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain zf-UBR PF02207.15 EAQ85764.1 - 7.9e-16 57.5 2.9 7.9e-16 57.5 2.0 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) FancD2 PF14631.1 EAQ85764.1 - 0.54 7.2 1.2 0.74 6.8 0.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MCM PF00493.18 EAQ85765.1 - 8.3e-117 389.6 6.7 5e-116 387.1 0.0 2.6 2 1 1 3 3 3 2 MCM2/3/5 family MCM2_N PF12619.3 EAQ85765.1 - 6.7e-31 107.3 37.3 6.7e-31 107.3 25.9 2.3 3 1 1 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EAQ85765.1 - 1.9e-20 73.5 0.1 4.6e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAQ85765.1 - 2.5e-07 30.0 0.0 5.3e-06 25.7 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAQ85765.1 - 2e-06 27.5 0.0 4.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EAQ85765.1 - 9.6e-05 21.9 0.1 0.00072 19.0 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EAQ85765.1 - 0.0024 17.4 0.1 0.017 14.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EAQ85765.1 - 0.036 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain HAD_2 PF13419.1 EAQ85766.1 - 1e-15 58.4 0.1 7.3e-15 55.6 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ85766.1 - 0.0022 17.6 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L18p PF00861.17 EAQ85767.1 - 1.4e-42 144.6 0.3 1.4e-42 144.6 0.2 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EAQ85767.1 - 8.8e-33 112.7 7.9 8.8e-33 112.7 5.5 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.1 EAQ85768.1 - 0.00032 20.4 9.6 51 4.3 0.0 7.9 7 0 0 7 7 7 3 Leucine Rich repeat DUF605 PF04652.11 EAQ85769.1 - 3.6 6.9 19.6 0.31 10.4 10.2 1.6 2 0 0 2 2 2 0 Vta1 like Med1 PF10744.4 EAQ85770.1 - 1e-34 119.9 0.0 9.8e-34 116.7 0.0 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 EAQ85771.1 - 1.2e-43 149.1 0.0 1.4e-42 145.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85771.1 - 9.1e-23 80.6 0.0 1.7e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85771.1 - 0.0039 16.1 0.0 0.021 13.7 0.0 2.0 1 1 0 1 1 1 1 Kinase-like MRC1 PF09444.5 EAQ85772.1 - 7.5e-46 156.0 22.0 7.5e-46 156.0 15.2 6.4 5 2 0 6 6 6 1 MRC1-like domain SAGA-Tad1 PF12767.2 EAQ85773.1 - 7.4e-35 120.8 0.0 3.5e-34 118.6 0.0 1.7 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 EAQ85774.1 - 7.7e-79 265.4 0.0 7.7e-39 133.4 0.1 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family Amidohydro_2 PF04909.9 EAQ85775.1 - 6.8e-06 25.8 0.1 1.6e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EAQ85775.1 - 0.0085 15.7 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family MFS_1 PF07690.11 EAQ85776.1 - 3.2e-17 62.2 53.5 2e-09 36.6 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EAQ85778.1 - 1.6e-22 79.6 0.0 2.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ85778.1 - 5e-06 26.3 15.4 8.8e-06 25.5 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 EAQ85778.1 - 2.1 7.0 4.1 4.3 6.0 2.8 1.4 1 0 0 1 1 1 0 Clusterin DHquinase_I PF01487.10 EAQ85781.1 - 3e-44 151.3 0.0 4.3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHO_dh PF01180.16 EAQ85782.1 - 1.1e-17 64.0 0.0 6.1e-16 58.2 0.0 2.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase RNA_Me_trans PF04252.8 EAQ85783.1 - 8.5e-50 168.8 0.0 9.7e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 EAQ85784.1 - 3.3e-113 378.9 0.0 4.3e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EAQ85784.1 - 0.00055 19.8 0.0 0.002 18.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family CIAPIN1 PF05093.8 EAQ85785.1 - 1.9e-35 120.9 3.5 3.1e-35 120.2 2.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HABP4_PAI-RBP1 PF04774.10 EAQ85786.1 - 0.00048 20.5 3.3 0.00078 19.9 2.3 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Formyl_trans_N PF00551.14 EAQ85787.1 - 4.4e-10 39.3 0.0 7.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Pex19 PF04614.7 EAQ85789.1 - 2.4e-74 250.1 12.5 2.4e-74 250.1 8.7 1.8 2 0 0 2 2 2 1 Pex19 protein family ATG_C PF09333.6 EAQ85789.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 ATG C terminal domain FliE PF02049.13 EAQ85789.1 - 0.36 10.8 8.3 0.24 11.4 2.1 3.0 1 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE GET2 PF08690.5 EAQ85789.1 - 5.8 6.0 10.8 0.4 9.8 3.3 1.9 1 1 1 2 2 2 0 GET complex subunit GET2 UQ_con PF00179.21 EAQ85790.1 - 3e-48 162.8 0.1 3.4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ85790.1 - 0.00097 18.9 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAQ85790.1 - 0.074 12.9 1.0 0.14 12.0 0.7 1.8 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 EAQ85791.1 - 1.9e-67 227.4 0.0 2.6e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EAQ85791.1 - 6.7e-37 126.0 0.0 1.2e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EAQ85791.1 - 1.5e-28 99.4 0.0 3.7e-28 98.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EAQ85791.1 - 6.7e-09 35.2 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EAQ85791.1 - 0.00055 18.9 0.0 0.0023 16.8 0.0 1.8 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EAQ85791.1 - 0.00078 18.2 0.0 0.3 9.7 0.0 2.9 1 1 2 3 3 3 1 Glutamine amidotransferases class-II Porin_3 PF01459.17 EAQ85792.1 - 3.1e-67 226.7 9.7 3.4e-67 226.6 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Peptidase_M24 PF00557.19 EAQ85793.1 - 1.2e-46 158.9 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 EAQ85793.1 - 0.027 13.7 0.1 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PRELI PF04707.9 EAQ85794.1 - 5.2e-42 143.0 0.2 6.4e-42 142.7 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 EAQ85794.1 - 0.051 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF605 PF04652.11 EAQ85795.1 - 7.9 5.7 8.0 8.5 5.6 5.5 1.0 1 0 0 1 1 1 0 Vta1 like DUF3618 PF12277.3 EAQ85797.1 - 1.2 9.2 8.5 0.059 13.4 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) ABC1 PF03109.11 EAQ85799.1 - 1e-30 106.1 0.0 1.7e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family 2OG-FeII_Oxy_3 PF13640.1 EAQ85800.1 - 1.4e-07 31.9 0.0 1.5e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_76 PF03663.9 EAQ85802.1 - 5.3e-103 345.2 13.0 9.8e-100 334.4 9.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EAQ85802.1 - 0.042 12.8 2.0 0.57 9.1 0.0 2.3 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Gln-synt_C PF00120.19 EAQ85803.1 - 1.7e-57 194.5 0.0 5.8e-57 192.7 0.0 1.9 3 0 0 3 3 3 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EAQ85803.1 - 3.6e-27 95.6 0.2 2.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase MR_MLE_C PF13378.1 EAQ85803.1 - 0.12 12.3 0.2 0.41 10.6 0.1 1.9 1 0 0 1 1 1 0 Enolase C-terminal domain-like ERGIC_N PF13850.1 EAQ85804.1 - 1.7e-21 76.0 0.0 2.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.7 EAQ85804.1 - 6.7e-16 58.5 0.1 9.2e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter DUF3922 PF13059.1 EAQ85804.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) AAT PF03417.11 EAQ85805.1 - 4.8e-16 58.9 0.0 7.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF733 PF05306.6 EAQ85805.1 - 0.05 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF733) NAAA-beta PF15508.1 EAQ85805.1 - 0.1 12.9 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.27 EAQ85807.1 - 2.3e-26 90.6 0.1 0.0002 21.1 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EAQ85808.1 - 9.4e-17 61.4 0.0 2.3e-14 53.7 0.0 2.9 2 1 0 2 2 2 2 Cytidylyltransferase Aminotran_4 PF01063.14 EAQ85811.1 - 5.2e-22 78.4 0.0 7.8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV AhpC-TSA_2 PF13911.1 EAQ85812.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AAA_12 PF13087.1 EAQ85813.1 - 1.7e-61 207.0 0.0 4.5e-61 205.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.5 EAQ85813.1 - 9.9e-57 190.7 0.6 1.2e-55 187.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 EAQ85813.1 - 2e-56 191.2 2.5 3.2e-56 190.5 1.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ85813.1 - 7.7e-15 54.4 0.1 1.8e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAQ85813.1 - 7.8e-12 45.1 0.2 1.9e-10 40.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EAQ85813.1 - 5.9e-08 32.7 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EAQ85813.1 - 2.4e-05 23.9 0.1 0.23 10.9 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EAQ85813.1 - 0.00012 21.7 0.7 0.00024 20.8 0.0 2.0 2 0 0 2 2 1 1 Helicase DUF2075 PF09848.4 EAQ85813.1 - 0.00018 20.5 1.0 0.0016 17.4 0.1 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EAQ85813.1 - 0.00036 19.9 0.1 0.0084 15.4 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EAQ85813.1 - 0.00042 19.3 0.3 0.2 10.6 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 EAQ85813.1 - 0.0014 18.1 0.1 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase KaiC PF06745.8 EAQ85813.1 - 0.013 14.6 0.0 0.043 12.9 0.0 1.7 2 0 0 2 2 2 0 KaiC SRP54 PF00448.17 EAQ85813.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EAQ85813.1 - 0.036 13.5 0.0 0.52 9.6 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EAQ85813.1 - 0.039 13.9 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EAQ85813.1 - 0.041 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAQ85813.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family UvrD_C_2 PF13538.1 EAQ85813.1 - 0.096 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 EAQ85813.1 - 0.1 11.7 0.0 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.9 EAQ85813.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EAQ85813.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Brix PF04427.13 EAQ85814.1 - 7.2e-45 152.9 0.4 9.1e-45 152.6 0.3 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.20 EAQ85815.1 - 0.0017 18.5 0.6 0.0017 18.5 0.4 2.2 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 EAQ85815.1 - 0.0022 17.6 3.6 0.0029 17.2 0.9 2.2 2 0 0 2 2 2 1 SNARE domain DUF3018 PF11455.3 EAQ85815.1 - 0.0096 15.8 1.9 0.064 13.1 0.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3018) TINF2_N PF14973.1 EAQ85815.1 - 0.034 14.2 1.4 0.091 12.8 1.0 1.8 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus FAA_hydrolase_N PF09298.6 EAQ85815.1 - 0.06 13.3 1.8 0.88 9.5 0.1 2.5 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal FlaC_arch PF05377.6 EAQ85815.1 - 0.067 13.0 2.1 4.1 7.3 0.0 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YlqD PF11068.3 EAQ85815.1 - 6.7 6.7 12.5 1.1 9.2 5.4 2.0 2 0 0 2 2 2 0 YlqD protein TPR_11 PF13414.1 EAQ85816.1 - 1.6e-49 165.4 19.1 1e-14 53.9 0.4 6.4 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EAQ85816.1 - 1.2e-41 138.6 19.5 1.5e-07 30.7 0.0 10.1 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ85816.1 - 1.4e-39 130.8 17.7 2.9e-06 26.7 0.0 10.3 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ85816.1 - 1.4e-25 89.2 12.8 2.2e-08 34.5 0.0 6.7 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ85816.1 - 6.4e-22 77.2 18.6 4.7e-07 29.6 0.3 7.0 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ85816.1 - 6.9e-22 75.7 7.9 0.0049 16.9 0.0 7.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ85816.1 - 2.6e-15 54.9 15.1 0.00055 19.5 0.0 9.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ85816.1 - 4.8e-15 54.7 14.2 0.0014 19.1 0.0 9.0 4 3 4 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ85816.1 - 7.7e-14 51.7 13.4 4.2e-06 26.9 0.7 6.3 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ85816.1 - 6.2e-12 45.1 8.7 0.02 14.7 0.0 6.4 4 2 4 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EAQ85816.1 - 1.9e-10 40.7 13.6 0.00039 20.4 0.2 5.0 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EAQ85816.1 - 8.1e-10 37.7 19.8 0.038 13.7 0.2 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 EAQ85816.1 - 9.7e-08 31.4 4.5 0.076 12.0 0.3 4.6 2 1 0 3 3 3 3 Tetratricopeptide repeat DUF3856 PF12968.2 EAQ85816.1 - 0.00013 21.7 3.7 1.2 8.9 0.0 4.9 4 2 0 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EAQ85816.1 - 0.00028 21.1 17.9 4.4 7.9 0.4 9.2 10 1 0 10 10 8 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EAQ85816.1 - 0.00035 19.7 5.8 0.28 10.4 0.0 5.4 6 0 0 6 6 5 1 SHNi-TPR NYD-SP12_N PF15015.1 EAQ85816.1 - 0.00075 17.8 0.5 0.0027 16.0 0.4 1.8 1 1 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_10 PF13374.1 EAQ85816.1 - 0.0079 16.0 10.4 1.5 8.8 0.5 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EAQ85816.1 - 0.0084 15.7 3.9 0.06 12.9 0.1 3.5 3 0 0 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 EAQ85816.1 - 0.026 14.6 5.5 2.6 8.2 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat MAS20 PF02064.10 EAQ85816.1 - 0.21 11.5 1.6 16 5.4 0.0 3.6 3 1 0 3 3 3 0 MAS20 protein import receptor Sel1 PF08238.7 EAQ85816.1 - 1.2 9.8 7.2 1.6 9.4 0.2 3.8 3 0 0 3 3 3 0 Sel1 repeat NARP1 PF12569.3 EAQ85816.1 - 4.3 5.9 16.6 2.1 6.9 0.0 4.1 4 1 0 4 4 3 0 NMDA receptor-regulated protein 1 Asp PF00026.18 EAQ85817.1 - 2.1e-53 181.6 1.3 3.7e-53 180.8 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Aminotran_4 PF01063.14 EAQ85817.1 - 1.5e-17 63.8 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Asp_protease_2 PF13650.1 EAQ85817.1 - 0.00075 19.9 0.2 0.59 10.6 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EAQ85817.1 - 0.0033 17.3 0.2 0.015 15.2 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal NKWYS PF10364.4 EAQ85817.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Btz PF09405.5 EAQ85818.1 - 1.3e-29 102.9 0.6 1.3e-29 102.9 0.4 2.1 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding UPF0052 PF01933.13 EAQ85819.1 - 7.9e-31 107.4 0.0 1.3e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ZZ PF00569.12 EAQ85820.1 - 1e-17 63.3 59.8 6.5e-06 25.5 4.2 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type RRM_1 PF00076.17 EAQ85821.1 - 2.7e-18 65.3 0.2 6.1e-13 48.2 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ85821.1 - 7.2e-16 57.9 0.0 2.4e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ85821.1 - 1.9e-06 27.5 0.1 0.00077 19.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cut8_C PF08559.5 EAQ85822.1 - 7.3e-49 165.2 0.0 9.5e-49 164.8 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EAQ85822.1 - 3.5e-17 61.8 0.6 7.2e-17 60.8 0.4 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EAQ85822.1 - 3.3e-09 36.5 0.5 7e-09 35.5 0.3 1.6 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Rad52_Rad22 PF04098.10 EAQ85823.1 - 3.7e-59 198.8 0.0 5.1e-59 198.4 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Calsequestrin PF01216.12 EAQ85823.1 - 0.28 9.9 0.4 0.41 9.3 0.3 1.2 1 0 0 1 1 1 0 Calsequestrin PAT1 PF09770.4 EAQ85823.1 - 0.59 8.3 25.0 1.2 7.2 17.3 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF566 PF04484.7 EAQ85823.1 - 5.8 6.3 9.0 9.7 5.5 6.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Aconitase PF00330.15 EAQ85824.1 - 5.5e-154 513.0 0.0 1.6e-153 511.5 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAQ85824.1 - 2.6e-38 131.0 0.0 4.5e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain APH PF01636.18 EAQ85825.1 - 1.6e-08 34.6 1.3 2.4e-08 34.0 0.9 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ85825.1 - 0.00037 20.1 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HEAT PF02985.17 EAQ85827.1 - 2.1e-08 33.5 1.2 0.043 13.8 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EAQ85827.1 - 0.00094 19.6 0.0 1.2 9.6 0.0 3.0 2 1 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.2 EAQ85827.1 - 0.0096 15.7 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.20 EAQ85827.1 - 0.026 13.6 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Adaptin_N PF01602.15 EAQ85827.1 - 0.11 10.7 0.0 0.28 9.4 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region Nop14 PF04147.7 EAQ85827.1 - 2.7 5.7 5.5 14 3.4 3.5 1.9 2 0 0 2 2 2 0 Nop14-like family DUF3439 PF11921.3 EAQ85827.1 - 5.9 6.6 11.3 0.15 11.8 2.6 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) WD40 PF00400.27 EAQ85828.1 - 1.1e-48 161.3 19.7 1.9e-12 46.5 0.3 7.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EAQ85828.1 - 1.7e-09 36.3 4.0 0.028 12.5 0.1 4.9 2 1 1 5 5 5 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 EAQ85828.1 - 0.00087 17.6 0.0 0.0015 16.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) FHA PF00498.21 EAQ85830.1 - 4.7e-12 45.8 0.0 1.1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Daxx PF03344.10 EAQ85830.1 - 8.6 4.7 21.5 0.79 8.1 11.5 1.5 1 1 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EAQ85830.1 - 8.9 4.0 20.5 18 3.0 14.2 1.5 1 0 0 1 1 1 0 Nop14-like family IFRD PF05004.8 EAQ85831.1 - 3.3e-31 108.5 4.2 4.1e-31 108.2 2.9 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EAQ85831.1 - 5.2e-05 23.4 0.5 0.0074 16.5 0.1 2.5 1 1 0 2 2 2 1 HEAT repeats Adaptin_N PF01602.15 EAQ85831.1 - 0.077 11.3 0.0 0.16 10.2 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region HEAT_EZ PF13513.1 EAQ85831.1 - 0.085 13.3 2.4 17 6.0 0.0 3.8 1 1 3 4 4 4 0 HEAT-like repeat GHMP_kinases_N PF00288.21 EAQ85834.1 - 3.2e-12 46.3 0.0 6.9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EAQ85834.1 - 8e-06 25.9 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Methyltransf_23 PF13489.1 EAQ85836.1 - 0.0048 16.6 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAQ85837.1 - 1.3e-17 63.7 0.0 7.9e-10 38.3 0.0 2.5 2 1 0 2 2 2 2 O-methyltransferase Actin PF00022.14 EAQ85838.1 - 1.7e-107 359.2 0.0 6.6e-71 238.8 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.8 EAQ85838.1 - 0.0031 16.1 0.1 0.16 10.5 0.1 2.8 1 1 0 1 1 1 1 MreB/Mbl protein DUF3602 PF12223.3 EAQ85839.1 - 1.4e-15 57.4 9.3 3.8e-13 49.6 2.9 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Chitin_synth_1 PF01644.12 EAQ85840.1 - 1.6e-80 268.6 0.3 2e-80 268.3 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EAQ85840.1 - 3.9e-10 38.7 0.0 7.1e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Sec1 PF00995.18 EAQ85841.1 - 7.6e-109 364.8 0.0 2.2e-87 294.0 0.0 2.0 1 1 1 2 2 2 2 Sec1 family DUF1351 PF07083.6 EAQ85841.1 - 0.028 14.0 1.8 0.65 9.5 0.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1351) DUF4646 PF15496.1 EAQ85841.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) zf-CCCH PF00642.19 EAQ85842.1 - 0.004 16.8 2.2 0.0076 15.9 1.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PRP38_assoc PF12871.2 EAQ85842.1 - 0.0051 17.3 4.1 0.0051 17.3 2.8 4.0 3 2 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-CCCH_2 PF14608.1 EAQ85842.1 - 0.039 13.9 2.6 0.068 13.1 1.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Flavoprotein PF02441.14 EAQ85843.1 - 1.5e-11 44.0 0.0 1.3e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Flavoprotein SHNi-TPR PF10516.4 EAQ85844.1 - 5.1e-16 57.6 0.1 2.5e-15 55.4 0.0 2.3 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 EAQ85844.1 - 3.1e-07 30.2 6.6 0.00027 20.8 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ85844.1 - 1.2e-05 24.8 7.1 0.00014 21.4 0.8 3.4 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 EAQ85844.1 - 1.2e-05 25.8 1.2 1.2e-05 25.8 0.8 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EAQ85844.1 - 0.00014 21.5 3.6 0.00034 20.3 2.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ85844.1 - 0.00029 20.8 2.0 0.0084 16.2 0.1 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EAQ85844.1 - 0.0006 20.1 0.6 0.0006 20.1 0.4 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ85844.1 - 0.011 15.8 1.4 0.22 11.8 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ85844.1 - 0.041 13.7 12.1 0.23 11.4 1.6 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ85844.1 - 0.11 12.2 2.0 0.67 9.6 1.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ85844.1 - 0.14 12.1 0.2 0.14 12.1 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ85844.1 - 0.38 10.6 2.6 46 4.1 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Pox_Ag35 PF03286.9 EAQ85844.1 - 4.4 6.7 13.1 0.03 13.8 2.8 2.0 2 1 0 2 2 2 0 Pox virus Ag35 surface protein RabGAP-TBC PF00566.13 EAQ85845.1 - 4e-48 163.7 0.0 9.4e-48 162.5 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 EAQ85846.1 - 5.9e-37 125.1 0.1 2.7e-17 62.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ85846.1 - 6.5e-29 99.7 2.2 1.8e-14 53.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ85846.1 - 1.2e-12 47.4 0.0 7.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAQ85846.1 - 0.0023 17.6 0.1 0.3 10.9 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PhyH PF05721.8 EAQ85847.1 - 3.8e-57 193.7 0.0 4.8e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3439 PF11921.3 EAQ85847.1 - 0.013 15.1 0.9 0.02 14.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) p450 PF00067.17 EAQ85848.1 - 1.5e-47 162.1 0.0 6.8e-47 160.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Daxx PF03344.10 EAQ85848.1 - 0.011 14.2 8.4 0.016 13.7 5.8 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EAQ85848.1 - 0.033 12.1 8.4 0.045 11.6 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 EAQ85848.1 - 0.043 13.8 8.9 0.078 13.0 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BSP_II PF05432.6 EAQ85848.1 - 0.058 12.6 14.9 0.096 11.9 10.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 EAQ85848.1 - 0.16 12.2 9.4 0.36 11.0 6.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.13 EAQ85848.1 - 0.27 10.3 10.3 0.48 9.5 7.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.3 EAQ85848.1 - 0.29 11.0 14.3 0.63 9.9 9.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 EAQ85848.1 - 0.49 9.8 8.4 0.97 8.9 5.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EAQ85848.1 - 0.55 8.1 6.3 0.8 7.6 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 EAQ85848.1 - 0.59 8.7 5.9 0.9 8.1 4.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TRAP_alpha PF03896.11 EAQ85848.1 - 0.68 8.8 10.3 1.2 8.0 7.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 EAQ85848.1 - 0.92 8.6 6.6 1.5 8.0 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.9 EAQ85848.1 - 1.5 9.0 25.2 3.3 7.9 17.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family RR_TM4-6 PF06459.7 EAQ85848.1 - 1.9 8.3 10.0 6.7 6.5 6.5 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pox_RNA_Pol_19 PF05320.7 EAQ85848.1 - 2 8.1 9.1 4.5 6.9 6.3 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FAM176 PF14851.1 EAQ85848.1 - 4.7 6.8 8.9 9 5.9 6.2 1.4 1 0 0 1 1 1 0 FAM176 family VID27 PF08553.5 EAQ85848.1 - 5.3 5.1 11.4 9.3 4.3 7.9 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EAQ85848.1 - 5.5 5.5 14.8 9.8 4.7 9.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 EAQ85848.1 - 8.2 5.0 14.3 13 4.4 9.9 1.1 1 0 0 1 1 1 0 Paf1 ICL PF00463.16 EAQ85852.1 - 4.7e-284 942.4 0.8 5.3e-284 942.2 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EAQ85852.1 - 6.6e-12 45.1 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SNF2_N PF00176.18 EAQ85853.1 - 3.3e-56 190.2 0.1 4.5e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EAQ85853.1 - 8.3e-26 89.6 0.9 2e-25 88.4 0.6 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EAQ85853.1 - 2.1e-15 56.3 0.0 6.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ85853.1 - 4.6e-05 22.9 0.0 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ85853.1 - 0.00024 20.9 0.0 0.0015 18.3 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EAQ85853.1 - 0.022 13.5 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.1 EAQ85853.1 - 0.13 11.0 1.0 4.5 5.9 0.1 2.9 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 Ank_2 PF12796.2 EAQ85854.1 - 3.2e-37 126.7 7.5 3.3e-12 46.5 0.8 5.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ85854.1 - 2.2e-34 115.5 17.6 2.3e-05 23.9 0.1 8.2 7 1 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EAQ85854.1 - 8.4e-26 89.8 16.4 0.00014 22.3 0.0 8.7 5 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ85854.1 - 1.8e-23 82.0 21.6 1.3e-06 28.4 0.4 6.9 6 1 1 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85854.1 - 2.3e-20 70.6 12.5 0.00094 19.2 0.2 9.5 8 2 0 8 8 8 3 Ankyrin repeat AAA_16 PF13191.1 EAQ85854.1 - 3.7e-10 40.1 0.1 1.8e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EAQ85854.1 - 7.9e-07 28.8 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EAQ85854.1 - 0.00031 20.4 0.0 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA PF00004.24 EAQ85854.1 - 0.00076 19.6 0.0 0.0035 17.5 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ85854.1 - 0.00082 19.5 0.0 0.0029 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ85854.1 - 0.0031 17.4 0.0 2.4 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.9 EAQ85854.1 - 0.0053 16.0 0.0 0.015 14.6 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NB-ARC PF00931.17 EAQ85854.1 - 0.025 13.4 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AFG1_ATPase PF03969.11 EAQ85854.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase ABC_tran PF00005.22 EAQ85854.1 - 0.19 12.0 0.0 0.49 10.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 EAQ85854.1 - 0.19 10.6 0.2 1.2 8.0 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain LCAT PF02450.10 EAQ85854.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RNA_helicase PF00910.17 EAQ85854.1 - 0.22 11.6 0.0 0.83 9.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Acyl-CoA_dh_M PF02770.14 EAQ85855.1 - 1.1e-06 27.9 0.3 1.9e-05 24.0 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glyco_trans_2_3 PF13632.1 EAQ85856.1 - 4.1e-47 160.4 0.8 4.1e-47 160.4 0.6 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAQ85856.1 - 2.4e-07 30.8 0.1 2.1e-06 27.6 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAQ85856.1 - 3.9e-05 23.3 0.0 0.00016 21.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAQ85856.1 - 0.012 14.8 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 TrbE PF11100.3 EAQ85856.1 - 0.021 14.6 2.7 0.05 13.4 1.9 1.6 1 0 0 1 1 1 0 Conjugal transfer protein TrbE FYVE PF01363.16 EAQ85857.1 - 0.01 15.6 3.1 0.01 15.6 2.2 3.0 3 0 0 3 3 3 0 FYVE zinc finger MRP-L20 PF12824.2 EAQ85858.1 - 1.6e-57 194.0 3.6 2.3e-57 193.5 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Kelch_5 PF13854.1 EAQ85859.1 - 1.2e-08 34.6 1.3 1.9e-07 30.8 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 EAQ85859.1 - 0.00032 20.7 5.0 2.4 8.4 0.0 5.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EAQ85859.1 - 0.0011 19.0 0.7 1.1 9.5 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Herpes_gE PF02480.11 EAQ85859.1 - 0.035 12.3 0.0 0.052 11.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Yip1 PF04893.12 EAQ85859.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Yip1 domain PTR2 PF00854.16 EAQ85861.1 - 3.2e-27 95.2 4.9 3.2e-27 95.2 3.4 2.4 3 1 0 3 3 3 1 POT family MFS_1 PF07690.11 EAQ85861.1 - 2.9e-06 26.2 4.5 2.9e-06 26.2 3.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily RunxI PF08504.6 EAQ85861.1 - 0.061 13.7 1.3 0.68 10.4 0.0 2.8 3 0 0 3 3 3 0 Runx inhibition domain RVP PF00077.15 EAQ85863.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease GATase_2 PF00310.16 EAQ85864.1 - 5.8e-21 74.6 0.1 6e-16 58.1 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EAQ85864.1 - 3.1e-17 62.7 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EAQ85864.1 - 4.4e-16 58.7 0.0 8.4e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EAQ85864.1 - 6e-07 28.4 0.0 7.8e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.22 EAQ85864.1 - 3.6e-05 23.4 0.2 9.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Trehalase PF01204.13 EAQ85865.1 - 1e-193 644.6 0.0 1.2e-193 644.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EAQ85865.1 - 2.2e-17 62.0 0.5 3.7e-17 61.3 0.3 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Rubis-subs-bind PF09273.6 EAQ85866.1 - 4.4e-22 78.3 0.0 7.1e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EAQ85866.1 - 4.1e-09 36.9 0.0 2e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF1601 PF07671.6 EAQ85866.1 - 0.036 13.7 0.2 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DUF3405 PF11885.3 EAQ85867.1 - 3.5e-197 655.5 0.3 4e-197 655.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Glyco_hydro_10 PF00331.15 EAQ85870.1 - 1.4e-24 86.7 0.0 1.5e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_3 PF00933.16 EAQ85871.1 - 1.2e-53 182.0 0.1 1.8e-42 145.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ85871.1 - 2.8e-40 138.2 0.0 5.6e-39 133.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ85871.1 - 7.5e-23 80.2 0.4 1.7e-22 79.0 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Desulfoferrod_N PF06397.7 EAQ85871.1 - 0.19 11.1 0.2 0.42 10.0 0.1 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain G-alpha PF00503.15 EAQ85872.1 - 1.5e-118 395.8 0.6 1.8e-118 395.6 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAQ85872.1 - 4.1e-14 52.1 1.0 1.5e-08 34.0 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAQ85872.1 - 0.00033 19.8 0.7 0.077 12.1 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EAQ85872.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ85872.1 - 0.05 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EAQ85872.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Spermine_synth PF01564.12 EAQ85874.1 - 2.3e-99 331.2 0.0 3.1e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EAQ85874.1 - 0.0006 19.4 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85874.1 - 0.00065 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ85874.1 - 0.00088 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ85874.1 - 0.0013 19.1 0.3 0.0042 17.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EAQ85874.1 - 0.0024 16.9 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 EAQ85874.1 - 0.017 14.3 0.2 0.15 11.2 0.1 2.2 1 1 1 2 2 2 0 O-methyltransferase MTS PF05175.9 EAQ85874.1 - 0.021 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EAQ85874.1 - 0.022 14.4 0.0 0.08 12.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EAQ85874.1 - 0.074 13.8 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 EAQ85874.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase CN_hydrolase PF00795.17 EAQ85875.1 - 1.8e-20 73.1 0.0 2.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AT_hook PF02178.14 EAQ85876.1 - 0.83 9.5 7.3 1.9 8.4 5.0 1.6 1 0 0 1 1 1 0 AT hook motif Uds1 PF15456.1 EAQ85877.1 - 6.1e-34 116.6 10.4 1.8e-33 115.1 7.2 1.8 1 0 0 1 1 1 1 Up-regulated During Septation Wbp11 PF09429.5 EAQ85877.1 - 0.1 12.5 5.3 0.079 12.9 0.5 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 Peptidase_M1 PF01433.15 EAQ85880.1 - 4.9e-72 243.1 0.0 6.5e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EAQ85880.1 - 1.8e-46 157.2 0.0 3.4e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EAQ85880.1 - 3.6e-16 59.3 0.1 6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EAQ85880.1 - 0.068 13.1 1.5 0.44 10.5 1.1 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Kinesin PF00225.18 EAQ85881.1 - 2.9e-111 371.4 2.5 3e-111 371.3 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EAQ85881.1 - 1.1e-27 96.4 0.0 2.8e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 EAQ85881.1 - 5.5e-06 26.4 0.0 3.9e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 EAQ85881.1 - 0.3 11.1 2.5 3.9 7.5 0.0 2.8 2 0 0 2 2 2 0 Kinesin protein 1B Methyltransf_23 PF13489.1 EAQ85883.1 - 1.7e-14 53.8 0.0 2.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ85883.1 - 9.5e-13 48.4 0.0 2.7e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAQ85883.1 - 6.4e-10 38.5 0.3 3.5e-07 29.5 0.1 2.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EAQ85883.1 - 1.7e-09 38.0 0.0 8.9e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ85883.1 - 5.5e-09 35.7 0.0 1.1e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ85883.1 - 1.1e-08 35.6 0.0 5.9e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ85883.1 - 4.4e-06 26.9 0.1 3.9e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ85883.1 - 0.00024 21.1 2.5 0.0019 18.1 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAQ85883.1 - 0.011 15.1 0.2 0.2 10.9 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.7 EAQ85883.1 - 0.087 12.1 0.1 0.52 9.5 0.1 2.0 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TruB_N PF01509.13 EAQ85885.1 - 8.6e-09 35.7 0.6 1.6e-08 34.8 0.4 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Sec2p PF06428.6 EAQ85886.1 - 4.4e-10 39.3 3.6 4.4e-10 39.3 2.5 2.4 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 EAQ85886.1 - 0.00066 19.3 8.6 0.035 13.7 0.2 2.1 2 0 0 2 2 2 2 IncA protein FUSC PF04632.7 EAQ85886.1 - 0.0046 15.4 17.2 0.038 12.4 4.3 2.0 2 0 0 2 2 2 2 Fusaric acid resistance protein family SlyX PF04102.7 EAQ85886.1 - 0.012 15.9 11.4 0.29 11.5 0.6 3.3 2 1 1 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.4 EAQ85886.1 - 0.015 15.3 6.8 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 KAR9 PF08580.5 EAQ85886.1 - 0.024 12.9 3.3 0.032 12.5 2.3 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 HOOK PF05622.7 EAQ85886.1 - 0.033 12.0 2.2 1.1 6.9 0.0 2.1 2 0 0 2 2 2 0 HOOK protein PAT1 PF09770.4 EAQ85886.1 - 0.1 10.8 13.5 0.13 10.5 9.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Laminin_II PF06009.7 EAQ85886.1 - 0.13 11.9 1.7 8.3 6.1 0.1 2.2 2 0 0 2 2 2 0 Laminin Domain II Myosin_tail_1 PF01576.14 EAQ85886.1 - 0.19 9.4 18.4 0.2 9.3 1.1 2.1 2 0 0 2 2 2 0 Myosin tail HAUS6_N PF14661.1 EAQ85886.1 - 0.46 9.8 5.9 0.23 10.7 0.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HR1 PF02185.11 EAQ85886.1 - 1.1 9.0 8.0 0.38 10.5 0.6 2.9 2 2 0 2 2 2 0 Hr1 repeat BBP1_C PF15272.1 EAQ85886.1 - 1.2 8.7 5.0 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF848 PF05852.6 EAQ85886.1 - 1.3 8.8 5.2 1.7 8.4 0.2 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) YscO PF07321.7 EAQ85886.1 - 1.8 8.3 15.8 1 9.2 1.2 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO DUF972 PF06156.8 EAQ85886.1 - 2 8.7 7.5 1 9.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Peptidase_S21 PF00716.12 EAQ85886.1 - 2.8 7.1 10.5 0.96 8.7 5.2 1.6 2 0 0 2 2 2 0 Assemblin (Peptidase family S21) Mito_fiss_reg PF05308.6 EAQ85886.1 - 4.3 6.6 32.4 0.32 10.3 13.5 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator MscS_porin PF12795.2 EAQ85886.1 - 7.6 5.7 22.9 1.5 8.0 7.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CASP_C PF08172.7 EAQ85886.1 - 7.9 5.4 11.1 0.59 9.1 0.3 2.1 2 0 0 2 2 2 0 CASP C terminal EXOSC1 PF10447.4 EAQ85887.1 - 4.8e-18 64.8 0.2 7.7e-18 64.2 0.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EAQ85887.1 - 3.9e-15 54.8 0.0 9.4e-15 53.6 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region ERG2_Sigma1R PF04622.7 EAQ85888.1 - 1.4e-94 315.3 0.3 1.6e-94 315.1 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NmrA PF05368.8 EAQ85889.1 - 9e-79 263.9 0.0 1.1e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ85889.1 - 2.2e-05 24.5 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding DUF2498 PF10692.4 EAQ85889.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Fcf1 PF04900.7 EAQ85890.1 - 1.4e-15 57.1 0.4 4.1e-15 55.6 0.1 1.8 2 0 0 2 2 2 1 Fcf1 Jag_N PF14804.1 EAQ85890.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Jag N-terminus RRM_1 PF00076.17 EAQ85893.1 - 6.3e-19 67.3 0.0 9.1e-19 66.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ85893.1 - 1.1e-16 60.5 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ85893.1 - 8.9e-11 41.4 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.6 EAQ85894.1 - 1.1e-79 266.1 0.0 7.4e-79 263.5 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 EAQ85894.1 - 0.023 12.9 0.4 0.55 8.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase SNF2_N PF00176.18 EAQ85895.1 - 1.1e-63 214.7 0.0 1.9e-63 214.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ85895.1 - 1.8e-12 46.9 0.0 5.6e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EAQ85895.1 - 2.8e-08 33.2 11.2 2.8e-08 33.2 7.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EAQ85895.1 - 1.2e-06 28.5 0.3 3.2e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAQ85895.1 - 1.3e-06 28.0 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EAQ85895.1 - 8.1e-05 22.5 9.6 8.1e-05 22.5 6.6 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ85895.1 - 0.00016 21.4 9.7 0.00016 21.4 6.7 2.2 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EAQ85895.1 - 0.0037 16.9 10.4 0.0037 16.9 7.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain CD99L2 PF12301.3 EAQ85895.1 - 0.046 13.4 2.2 0.097 12.3 1.6 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 zf-RING_6 PF14835.1 EAQ85895.1 - 0.061 13.1 3.3 0.15 11.8 2.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AAA_34 PF13872.1 EAQ85895.1 - 0.064 12.0 0.0 0.26 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.3 EAQ85895.1 - 6.4 6.3 9.8 1.3 8.6 3.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit LRR_8 PF13855.1 EAQ85896.1 - 3.2e-06 26.7 0.0 0.11 12.3 0.0 4.4 4 2 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EAQ85896.1 - 0.00059 19.6 3.5 0.14 12.3 0.0 5.8 8 0 0 8 8 8 1 Leucine Rich repeat LRR_7 PF13504.1 EAQ85896.1 - 0.0016 18.2 4.2 55 4.6 0.0 6.5 9 0 0 9 9 9 0 Leucine rich repeat GATA PF00320.22 EAQ85896.1 - 0.0099 15.2 4.4 0.02 14.2 0.8 2.4 2 0 0 2 2 2 1 GATA zinc finger FYVE_2 PF02318.11 EAQ85896.1 - 0.027 14.3 0.3 0.066 13.1 0.2 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger NARP1 PF12569.3 EAQ85896.1 - 1.1 7.8 5.3 1.7 7.3 3.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Malic_M PF03949.10 EAQ85897.1 - 2.4e-86 289.4 0.0 3.7e-86 288.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EAQ85897.1 - 2e-69 232.7 0.0 3.3e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain POT1 PF02765.12 EAQ85898.1 - 9.4e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.14 EAQ85899.1 - 6.5e-44 150.0 0.0 1.8e-27 95.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EAQ85899.1 - 2e-16 60.1 0.0 1.2e-15 57.6 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAQ85899.1 - 5.1e-16 59.3 0.4 4.5e-15 56.2 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ85899.1 - 2.5e-11 43.1 1.0 5e-09 35.5 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAQ85899.1 - 2.2e-09 37.4 0.0 2.6e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ85899.1 - 5.8e-07 28.8 0.0 4e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EAQ85899.1 - 7e-07 29.1 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ85899.1 - 0.00022 20.2 0.0 0.11 11.3 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ85899.1 - 0.0062 15.0 0.2 0.037 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.15 EAQ85899.1 - 0.016 15.2 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 EAQ85899.1 - 0.023 14.1 0.2 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 DJ-1/PfpI family FAD_binding_3 PF01494.14 EAQ85899.1 - 0.034 13.2 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EAQ85899.1 - 0.037 14.4 0.1 3.1 8.2 0.0 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EAQ85899.1 - 0.078 11.3 0.1 0.29 9.4 0.0 1.8 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Aminotran_1_2 PF00155.16 EAQ85900.1 - 3.1e-10 39.5 0.0 1.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II KH_dom-like PF14714.1 EAQ85900.1 - 0.08 12.9 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal LTV PF04180.9 EAQ85901.1 - 1.8e-103 347.2 10.7 2.3e-103 346.9 7.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EAQ85902.1 - 5.6e-18 64.9 0.1 1.6e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ85902.1 - 3.1e-07 29.8 0.1 1.5e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ85902.1 - 0.00017 21.4 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family DUF258 PF03193.11 EAQ85902.1 - 0.00034 19.8 0.0 0.001 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EAQ85902.1 - 0.0092 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EAQ85902.1 - 0.041 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EAQ85902.1 - 0.064 12.6 0.0 3 7.2 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ribosomal_L5_C PF00673.16 EAQ85903.1 - 6.1e-24 83.5 0.0 9.6e-24 82.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EAQ85903.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.5 EAQ85904.1 - 6.8e-37 125.8 2.2 1.4e-36 124.8 1.5 1.5 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.1 EAQ85904.1 - 2.8e-05 24.4 2.2 0.0004 20.7 0.3 2.6 2 2 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 EAQ85904.1 - 5.8e-05 22.7 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAQ85904.1 - 8.1e-05 22.8 2.3 0.00082 19.6 1.6 2.5 1 1 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EAQ85904.1 - 0.0035 17.2 0.3 0.45 10.7 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat AAA_22 PF13401.1 EAQ85904.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Actin PF00022.14 EAQ85905.1 - 1.6e-149 497.6 0.0 1.1e-148 494.9 0.0 1.8 1 1 0 1 1 1 1 Actin ESSS PF10183.4 EAQ85905.1 - 0.034 14.5 0.0 0.11 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RF-1 PF00472.15 EAQ85906.1 - 7.9e-05 22.4 4.2 0.0016 18.2 0.1 2.3 1 1 1 2 2 2 2 RF-1 domain TT_ORF2 PF02957.10 EAQ85906.1 - 0.34 11.6 6.0 0.28 11.9 2.9 1.7 1 1 0 1 1 1 0 TT viral ORF2 WD40 PF00400.27 EAQ85907.1 - 4.9e-62 203.7 13.9 1.1e-06 28.2 0.0 12.4 12 0 0 12 12 12 10 WD domain, G-beta repeat zf-C2H2 PF00096.21 EAQ85908.1 - 0.1 13.0 0.2 0.1 13.0 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-CHCC PF10276.4 EAQ85908.1 - 0.12 12.2 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain RRM_1 PF00076.17 EAQ85911.1 - 2.2e-33 113.6 0.0 1.5e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ85911.1 - 1.4e-16 60.0 0.0 3.9e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ85911.1 - 2.1e-16 59.6 0.0 4.1e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EAQ85911.1 - 0.0034 16.8 0.1 2.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 EAQ85911.1 - 0.056 13.2 0.0 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 MIF4G_like PF09088.6 EAQ85912.1 - 6.7e-87 289.8 0.1 1.1e-86 289.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EAQ85912.1 - 2.1e-52 177.8 0.1 3.4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EAQ85912.1 - 0.038 13.4 0.0 0.22 10.8 0.0 2.2 3 0 0 3 3 3 0 MIF4G domain Pkinase PF00069.20 EAQ85913.1 - 8e-64 215.2 0.0 9.5e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85913.1 - 9.8e-26 90.3 0.0 1.3e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85913.1 - 5.5e-08 32.1 0.0 2.7e-07 29.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EAQ85913.1 - 0.00055 19.7 0.2 0.0036 17.0 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ85913.1 - 0.04 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0220 PF05255.6 EAQ85915.1 - 1.2e-62 210.0 3.2 1.3e-62 209.9 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) UCR_6-4kD PF08997.5 EAQ85915.1 - 0.026 14.2 1.6 0.055 13.1 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein SMI1_KNR4 PF09346.5 EAQ85916.1 - 4.3e-37 127.0 0.0 6.6e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Chorion_2 PF03964.10 EAQ85916.1 - 0.072 13.6 0.1 0.072 13.6 0.1 3.6 3 1 0 3 3 3 0 Chorion family 2 Sec8_exocyst PF04048.9 EAQ85917.1 - 5.4e-14 52.0 0.1 1.7e-06 27.7 0.0 2.5 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain IZUMO PF15005.1 EAQ85917.1 - 0.44 10.5 1.0 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion RAI1 PF08652.6 EAQ85918.1 - 6.3e-28 96.3 0.0 1.2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease ResIII PF04851.10 EAQ85918.1 - 0.029 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 EAQ85919.1 - 9.8e-57 192.0 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85919.1 - 6.3e-40 136.8 0.0 9.5e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85919.1 - 9.3e-05 21.5 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1777 PF08648.7 EAQ85919.1 - 0.0054 16.4 7.3 0.0054 16.4 5.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Transglut_core PF01841.14 EAQ85920.1 - 5.4e-12 45.9 0.2 2.8e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EAQ85920.1 - 2.2e-08 33.4 0.2 4.4e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ85920.1 - 3.3e-05 23.1 2.6 4.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EAQ85920.1 - 9.1e-05 21.9 0.1 0.00024 20.6 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain ABC_tran PF00005.22 EAQ85921.1 - 1.1e-13 51.6 0.1 8.9e-13 48.7 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAQ85921.1 - 8.9e-10 38.9 0.0 0.00033 20.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EAQ85921.1 - 0.0002 20.5 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EAQ85921.1 - 0.00079 18.9 0.2 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EAQ85921.1 - 0.0012 16.3 0.4 0.0016 15.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_16 PF13191.1 EAQ85921.1 - 0.002 18.1 0.2 0.0043 17.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 EAQ85921.1 - 0.0035 16.8 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EAQ85921.1 - 0.0035 16.6 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Arf PF00025.16 EAQ85921.1 - 0.0077 15.4 0.0 0.015 14.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_23 PF13476.1 EAQ85921.1 - 0.0078 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAQ85921.1 - 0.011 15.6 0.9 0.026 14.4 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EAQ85921.1 - 0.014 15.5 0.2 0.051 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ85921.1 - 0.017 15.8 0.5 0.034 14.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAQ85921.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EAQ85921.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EAQ85921.1 - 0.04 14.1 0.1 0.16 12.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAQ85921.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAQ85921.1 - 0.043 13.2 0.4 0.094 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAQ85921.1 - 0.052 13.0 0.1 0.13 11.7 0.0 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EAQ85921.1 - 0.071 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Dynamin family SRP54 PF00448.17 EAQ85921.1 - 0.12 11.8 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 EAQ85921.1 - 0.12 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ85921.1 - 0.14 11.7 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EAQ85921.1 - 0.22 10.9 0.3 0.36 10.2 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CENP-I PF07778.6 EAQ85922.1 - 5.8e-90 301.9 0.8 4.6e-52 176.8 0.0 2.1 1 1 1 2 2 2 2 Mis6 Acetyltransf_1 PF00583.19 EAQ85923.1 - 6.7e-06 26.0 0.1 3.7e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAQ85923.1 - 0.0011 19.0 0.1 0.0052 16.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAQ85923.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAQ85923.1 - 0.032 14.0 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3384 PF11864.3 EAQ85924.1 - 1.7e-110 369.6 0.0 2.5e-109 365.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EAQ85924.1 - 9.6e-43 145.7 0.1 1e-34 119.5 0.0 2.6 1 1 1 2 2 2 2 Rap/ran-GAP Tuberin PF03542.11 EAQ85924.1 - 4.6e-29 101.6 3.7 5.8e-26 91.3 0.9 2.5 2 0 0 2 2 2 2 Tuberin CAS_CSE1 PF03378.10 EAQ85925.1 - 2.4e-178 592.8 0.0 1.5e-177 590.3 0.0 2.2 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EAQ85925.1 - 2.7e-146 486.9 0.7 4.2e-146 486.2 0.5 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EAQ85925.1 - 1.4e-11 44.0 0.0 4.6e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EAQ85925.1 - 0.012 15.8 0.8 0.17 12.1 0.0 3.1 3 1 0 3 3 3 0 HEAT repeats Xpo1 PF08389.7 EAQ85925.1 - 0.021 14.7 1.0 2.9 7.7 0.0 3.8 3 2 0 3 3 3 0 Exportin 1-like protein Nop14 PF04147.7 EAQ85926.1 - 0.046 11.6 4.7 0.061 11.2 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EAQ85926.1 - 1.1 8.8 10.3 2.5 7.7 7.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 EAQ85926.1 - 2.9 7.0 5.8 4.2 6.5 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EAQ85926.1 - 6 4.7 6.3 8.5 4.2 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 EAQ85927.1 - 8.1e-44 149.7 0.0 2.3e-43 148.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85927.1 - 2e-23 82.7 0.0 2.6e-20 72.5 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85927.1 - 9.6e-05 21.4 0.1 0.00059 18.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAQ85927.1 - 0.0015 18.2 0.6 0.046 13.4 0.4 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EAQ85927.1 - 0.0033 16.5 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EAQ85927.1 - 0.067 12.0 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EAQ85927.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 EAQ85928.1 - 6.2e-30 101.9 6.6 4.3e-06 26.3 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EAQ85928.1 - 1.8e-06 27.8 0.0 1.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 EAQ85928.1 - 0.00059 19.5 0.1 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Nup160 PF11715.3 EAQ85928.1 - 0.021 12.9 1.2 0.23 9.5 1.1 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 EAQ85928.1 - 0.085 11.9 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EAQ85928.1 - 0.13 11.9 0.1 15 5.3 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF4221 PF13970.1 EAQ85928.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Dynamin_M PF01031.15 EAQ85929.1 - 6e-107 356.8 0.7 8.6e-107 356.3 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EAQ85929.1 - 4.1e-57 192.6 0.0 7.5e-57 191.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EAQ85929.1 - 1.1e-28 98.9 6.4 1.3e-28 98.6 2.8 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAQ85929.1 - 4.1e-05 23.5 0.2 0.00081 19.3 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ85929.1 - 0.01 16.2 0.0 0.032 14.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein CoA_transf_3 PF02515.12 EAQ85930.1 - 9.9e-12 44.4 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Glutaredoxin PF00462.19 EAQ85931.1 - 0.00079 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin adh_short PF00106.20 EAQ85932.1 - 6.8e-13 48.8 1.2 2.9e-12 46.8 0.7 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ85932.1 - 9.3e-09 35.1 0.2 1.5e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ85932.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G_glu_transpept PF01019.16 EAQ85933.1 - 6.9e-120 400.9 0.0 1.6e-119 399.7 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase GST_N_2 PF13409.1 EAQ85934.1 - 4.5e-08 32.9 0.3 7e-08 32.3 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ85934.1 - 1.6e-07 31.3 0.1 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPTA PF01239.17 EAQ85934.1 - 0.021 14.1 0.8 0.044 13.1 0.6 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat tRNA-synt_1b PF00579.20 EAQ85935.1 - 4.3e-18 65.4 0.3 2.4e-10 40.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) RF-1 PF00472.15 EAQ85936.1 - 4.8e-34 116.5 3.4 1.1e-33 115.4 2.3 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EAQ85936.1 - 1.6e-27 95.4 0.1 5.9e-27 93.6 0.0 2.1 2 1 0 2 2 2 1 PCRF domain MIR PF02815.14 EAQ85936.1 - 0.048 13.2 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 MIR domain Peptidase_S10 PF00450.17 EAQ85937.1 - 2.1e-84 284.0 0.0 3e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2614 PF11023.3 EAQ85937.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) DWNN PF08783.6 EAQ85939.1 - 7.1e-28 96.3 0.0 1.5e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EAQ85939.1 - 0.00052 19.4 4.8 0.0023 17.3 3.3 2.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EAQ85939.1 - 0.01 15.7 1.5 0.01 15.7 1.0 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-RING_6 PF14835.1 EAQ85939.1 - 0.023 14.4 1.8 0.045 13.5 1.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EAQ85939.1 - 0.14 11.8 6.7 0.35 10.4 4.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EAQ85939.1 - 0.25 10.8 6.4 0.5 9.9 4.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE_2 PF02318.11 EAQ85939.1 - 0.27 11.1 2.3 0.31 10.9 0.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.1 EAQ85939.1 - 0.7 9.6 12.6 0.047 13.4 4.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EAQ85939.1 - 0.72 9.7 10.6 2.1 8.3 7.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAQ85939.1 - 2.2 8.0 9.9 4.3 7.0 6.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ85939.1 - 4.2 7.4 15.1 0.36 10.8 6.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.10 EAQ85940.1 - 4.4e-113 377.3 0.0 5e-113 377.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EAQ85940.1 - 1.8e-16 60.1 0.2 1e-15 57.6 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EAQ85940.1 - 1.9e-08 34.4 0.0 1.2e-07 31.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EAQ85940.1 - 4.1e-06 26.1 0.0 7.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EAQ85940.1 - 3.3e-05 23.4 0.2 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EAQ85940.1 - 0.0057 16.0 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ85940.1 - 0.009 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAQ85940.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 EAQ85940.1 - 0.025 13.9 0.0 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein MipZ PF09140.6 EAQ85940.1 - 0.025 13.6 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 EAQ85940.1 - 0.092 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EAQ85940.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EAQ85940.1 - 0.13 11.1 0.3 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Transthyretin PF00576.16 EAQ85941.1 - 7.5e-05 22.5 0.2 0.00011 22.0 0.1 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family zf-C4H2 PF10146.4 EAQ85941.1 - 0.085 12.8 0.2 0.089 12.7 0.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein SecE PF00584.15 EAQ85944.1 - 6.2e-08 32.1 0.0 8.3e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex MKT1_C PF12246.3 EAQ85945.1 - 1.8e-74 249.8 0.0 2.4e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EAQ85945.1 - 8e-29 99.8 0.0 1.9e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EAQ85945.1 - 0.00065 19.9 0.0 0.022 15.0 0.0 2.6 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EAQ85945.1 - 0.036 14.1 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 XPG I-region Monellin PF09200.5 EAQ85946.1 - 0.13 11.8 0.3 0.2 11.2 0.2 1.4 1 1 0 1 1 1 0 Monellin TrmE_N PF10396.4 EAQ85947.1 - 5e-21 74.7 0.0 1.4e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EAQ85947.1 - 1.2e-18 67.2 0.0 4.4e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EAQ85947.1 - 5.4e-18 65.0 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ85947.1 - 7e-07 28.6 0.0 5.8e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ85947.1 - 2.8e-05 23.9 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EAQ85947.1 - 0.00073 20.0 0.0 0.0024 18.3 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EAQ85947.1 - 0.0087 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.22 EAQ85947.1 - 0.0095 16.2 0.1 0.026 14.7 0.1 1.7 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 EAQ85947.1 - 0.015 14.7 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Phosphodiest PF01663.17 EAQ85947.1 - 0.024 13.9 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase AAA_24 PF13479.1 EAQ85947.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EAQ85947.1 - 0.098 11.8 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EAQ85947.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mak16 PF04874.9 EAQ85948.1 - 3.8e-23 81.4 36.8 2e-22 79.1 5.1 3.5 2 2 1 3 3 3 2 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 EAQ85948.1 - 5.1e-08 33.3 0.1 5.1e-08 33.3 0.1 2.0 3 0 0 3 3 3 1 Ribosomal L28e protein family TFIIA PF03153.8 EAQ85948.1 - 0.0028 17.6 11.9 0.0042 17.0 8.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EAQ85948.1 - 0.012 13.5 32.7 0.018 13.0 22.7 1.2 1 0 0 1 1 1 0 Nop14-like family PaaX_C PF08223.6 EAQ85948.1 - 0.016 14.8 1.4 0.032 13.9 0.9 1.5 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain CENP-T PF15511.1 EAQ85948.1 - 0.032 13.5 14.9 0.043 13.0 10.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Drc1-Sld2 PF11719.3 EAQ85948.1 - 3.8 6.5 21.0 0.068 12.2 9.7 1.5 2 0 0 2 2 2 0 DNA replication and checkpoint protein tRNA-synt_1 PF00133.17 EAQ85949.1 - 2e-144 481.8 0.0 5.6e-107 358.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAQ85949.1 - 1.4e-32 112.5 0.0 2.5e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAQ85949.1 - 1.2e-11 43.9 0.0 0.0035 16.0 0.0 4.1 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EAQ85949.1 - 0.15 11.1 0.0 0.78 8.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EAQ85949.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EAQ85949.1 - 0.34 9.6 0.0 2.6 6.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (R) Mso1_Sec1_bdg PF14475.1 EAQ85950.1 - 9.2e-19 66.5 0.0 1.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.13 EAQ85951.1 - 6.2e-36 123.8 1.0 1.5e-35 122.6 0.7 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EAQ85951.1 - 2.5e-09 36.7 0.0 5e-05 22.6 0.0 3.8 3 1 0 4 4 4 3 Domain of unknown function (DUF3548) Herpes_capsid PF06112.6 EAQ85951.1 - 0.014 15.4 2.8 0.014 15.4 1.9 2.6 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein Glyco_hydro_63 PF03200.11 EAQ85952.1 - 2.9e-247 822.5 0.0 3.3e-246 819.0 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EAQ85952.1 - 2.5e-05 23.1 0.2 4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EAQ85952.1 - 0.0071 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase bZIP_1 PF00170.16 EAQ85954.1 - 0.0093 15.9 6.0 0.017 15.0 4.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ85954.1 - 0.0098 15.7 8.9 0.018 14.8 6.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper IGR PF09597.5 EAQ85956.1 - 2.6e-24 84.8 0.0 4e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 EAQ85956.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SNF2_N PF00176.18 EAQ85957.1 - 4e-57 193.2 0.0 7.4e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EAQ85957.1 - 6.3e-09 35.5 10.1 1.3e-08 34.5 7.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAQ85957.1 - 1.6e-08 34.0 8.7 3.2e-08 33.1 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ85957.1 - 3.3e-08 33.0 9.1 6.3e-08 32.1 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ85957.1 - 9.1e-08 32.0 10.6 1.9e-07 31.0 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ85957.1 - 6.2e-06 25.8 9.5 1.1e-05 25.0 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAQ85957.1 - 8.3e-06 25.8 6.9 2.2e-05 24.4 4.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EAQ85957.1 - 9.7e-05 21.8 4.1 0.0002 20.7 2.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.26 EAQ85957.1 - 0.018 14.9 0.0 0.055 13.3 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EAQ85957.1 - 0.045 13.6 8.8 0.092 12.6 6.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EAQ85957.1 - 0.069 12.9 4.0 0.17 11.7 2.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EAQ85957.1 - 0.14 11.8 7.4 0.4 10.4 5.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EAQ85957.1 - 0.92 9.1 4.9 2.5 7.7 3.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EAQ85957.1 - 3.6 7.1 11.5 0.53 9.7 5.1 1.7 2 0 0 2 2 2 0 P-11 zinc finger Sec10 PF07393.6 EAQ85958.1 - 1.6e-190 634.8 0.0 1.9e-190 634.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EAQ85958.1 - 1e-07 31.5 0.3 4.4e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAQ85958.1 - 1.2e-07 31.2 0.1 2.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 EAQ85959.1 - 1e-63 214.9 0.0 1.5e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ85959.1 - 2e-32 112.2 0.0 2.7e-32 111.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ85959.1 - 0.00018 20.5 0.0 0.00037 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Frag1 PF10277.4 EAQ85960.1 - 7.7e-18 64.7 15.1 7e-09 35.4 6.2 2.1 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family Cytochrom_B_N PF00033.14 EAQ85960.1 - 0.0026 17.1 3.9 0.0048 16.2 2.6 1.5 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB PI31_Prot_C PF08577.6 EAQ85960.1 - 0.021 15.4 0.6 0.24 12.0 0.2 2.2 2 0 0 2 2 2 0 PI31 proteasome regulator DUF21 PF01595.15 EAQ85960.1 - 0.98 8.6 5.7 0.99 8.6 2.8 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF21 DUF4131 PF13567.1 EAQ85960.1 - 1 8.7 6.1 0.84 9.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3812 PF12757.2 EAQ85961.1 - 2e-38 131.2 15.4 2e-38 131.2 10.7 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3812) Ribosomal_L4 PF00573.17 EAQ85963.1 - 3.7e-41 140.6 1.1 5.1e-41 140.1 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EAQ85963.1 - 3.7e-28 97.2 0.8 9.1e-28 95.9 0.1 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_28 PF00295.12 EAQ85964.1 - 1.1e-34 119.8 7.2 1.5e-34 119.4 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 tRNA-synt_1g PF09334.6 EAQ85967.1 - 1.1e-105 353.4 0.6 9.2e-67 225.3 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EAQ85967.1 - 1.7e-24 85.8 2.2 3.2e-11 41.9 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.1 EAQ85967.1 - 7.2e-12 45.6 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 EAQ85967.1 - 4.3e-07 29.3 0.1 0.0081 15.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain FR47 PF08445.5 EAQ85967.1 - 0.0039 16.9 0.1 2.7 7.7 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.1 EAQ85967.1 - 0.004 17.0 0.0 0.28 11.0 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ85967.1 - 0.011 15.6 0.3 0.077 13.0 0.2 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PALP PF00291.20 EAQ85968.1 - 4.2e-41 141.1 0.6 5.2e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme RCC1 PF00415.13 EAQ85968.1 - 0.065 13.4 0.2 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat DNA_pol_E_B PF04042.11 EAQ85970.1 - 1.4e-52 177.9 0.0 1.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B WD40 PF00400.27 EAQ85971.1 - 1.1e-25 88.5 13.6 3e-06 26.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EAQ85971.1 - 1.3e-19 69.9 0.1 2.2e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EAQ85971.1 - 0.0021 16.2 3.5 0.82 7.7 0.2 3.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 RNA_pol_L_2 PF13656.1 EAQ85972.1 - 9.7e-18 63.3 0.0 2.3e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DNA_pol_A_exo1 PF01612.15 EAQ85972.1 - 3.6e-17 62.3 0.0 6.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease RNA_pol_L PF01193.19 EAQ85972.1 - 3.9e-06 25.8 0.0 1.2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Aa_trans PF01490.13 EAQ85973.1 - 4.1e-83 279.1 32.6 5e-83 278.8 22.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NDUF_B12 PF08122.7 EAQ85973.1 - 0.14 11.9 0.2 0.5 10.1 0.1 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family AA_permease PF00324.16 EAQ85974.1 - 2.6e-57 194.2 30.9 3.3e-57 193.8 21.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ85974.1 - 1.8e-14 53.1 37.8 2.4e-14 52.7 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease cobW PF02492.14 EAQ85975.1 - 1.2e-34 119.2 0.0 2.6e-34 118.2 0.0 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EAQ85975.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EAQ85975.1 - 0.018 14.7 0.5 0.054 13.2 0.2 1.9 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 EAQ85975.1 - 0.019 14.4 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CobW_C PF07683.9 EAQ85975.1 - 0.06 13.0 0.0 0.36 10.5 0.0 2.2 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 EAQ85975.1 - 0.12 12.5 0.0 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.7 EAQ85975.1 - 0.15 10.6 0.1 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 DUF1754 PF08555.5 EAQ85977.1 - 4.3e-19 68.9 10.8 7.3e-19 68.1 7.5 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DDHD PF02862.12 EAQ85977.1 - 0.1 12.3 1.5 0.13 12.0 1.0 1.2 1 0 0 1 1 1 0 DDHD domain SpoIIIAH PF12685.2 EAQ85977.1 - 0.59 9.5 3.8 0.75 9.2 2.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein HCMV_UL139 PF12507.3 EAQ85977.1 - 0.79 9.8 3.3 0.89 9.7 2.3 1.4 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein Host_attach PF10116.4 EAQ85977.1 - 0.94 9.6 6.4 0.85 9.8 3.1 1.9 1 1 1 2 2 2 0 Protein required for attachment to host cells IncA PF04156.9 EAQ85977.1 - 1.3 8.5 4.8 2.2 7.8 3.3 1.2 1 0 0 1 1 1 0 IncA protein Sigma70_ner PF04546.8 EAQ85977.1 - 6.1 6.3 9.9 12 5.4 6.9 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region PAT1 PF09770.4 EAQ85978.1 - 6 4.9 6.5 7.5 4.6 4.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CTP_transf_1 PF01148.15 EAQ85979.1 - 1.5e-05 24.7 10.6 1.5e-05 24.7 7.3 3.3 3 2 1 4 4 4 1 Cytidylyltransferase family ECH_C PF13766.1 EAQ85980.1 - 2.1e-32 111.7 0.4 5e-32 110.5 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EAQ85980.1 - 4.1e-26 91.6 0.0 7.4e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Dak1 PF02733.12 EAQ85981.1 - 9.5e-101 336.5 15.7 3.7e-100 334.6 10.9 1.7 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EAQ85981.1 - 1.3e-42 145.4 0.0 4e-42 143.8 0.0 1.9 2 0 0 2 2 2 1 DAK2 domain Glyco_hydro_76 PF03663.9 EAQ85982.1 - 5.2e-154 513.1 5.5 6.4e-154 512.8 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EAQ85982.1 - 0.014 14.4 6.5 1 8.3 0.1 3.5 2 2 2 4 4 4 0 Glycosyl Hydrolase Family 88 NAP PF00956.13 EAQ85983.1 - 5.2e-52 176.4 10.3 5.2e-52 176.4 7.2 2.1 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) SDA1 PF05285.7 EAQ85983.1 - 0.0071 15.6 17.1 0.015 14.6 11.9 1.4 1 0 0 1 1 1 1 SDA1 MSV199 PF10553.4 EAQ85983.1 - 0.044 13.6 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 MSV199 domain BUD22 PF09073.5 EAQ85983.1 - 0.13 11.3 17.4 0.2 10.7 12.0 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EAQ85983.1 - 8.3 4.1 24.7 17 3.1 17.1 1.4 1 0 0 1 1 1 0 Nop14-like family Asparaginase PF00710.15 EAQ85984.1 - 2.3e-101 338.7 0.0 2.9e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 EAQ85984.1 - 5.5e-13 48.0 1.0 8.6e-06 25.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EAQ85984.1 - 2.5e-10 40.5 0.1 4.7e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ85984.1 - 1.7e-08 34.4 3.4 4.4e-05 23.5 0.5 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ85984.1 - 8.4e-08 32.5 0.2 3.1e-07 30.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ85984.1 - 0.0076 16.4 0.3 9.3 6.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat BCS1_N PF08740.6 EAQ85986.1 - 7.3e-37 126.7 0.4 1.9e-36 125.4 0.3 1.7 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EAQ85986.1 - 6.9e-08 32.7 0.0 3.1e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Tau95 PF09734.4 EAQ85987.1 - 1.2e-71 241.6 0.0 1.6e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EAQ85988.1 - 1.4e-130 435.6 5.0 2.6e-111 372.1 3.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) CTD_bind PF04818.8 EAQ85989.1 - 3.4e-14 52.8 0.0 6.5e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Exo_endo_phos PF03372.18 EAQ85991.1 - 8.3e-28 97.9 0.1 1.6e-27 97.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4243 PF14027.1 EAQ85992.1 - 1.1e-93 314.3 0.1 1.4e-93 313.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) WD40 PF00400.27 EAQ85993.1 - 3.1e-53 175.8 28.2 3.5e-12 45.7 0.0 12.4 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 EAQ85993.1 - 1.7e-26 92.3 0.0 2.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EAQ85993.1 - 5.8e-06 26.1 4.2 0.096 12.3 0.0 6.3 5 1 2 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAQ85993.1 - 2.4e-05 22.6 0.9 0.32 9.0 0.0 4.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EAQ85993.1 - 0.00017 20.7 0.4 0.99 8.4 0.0 4.4 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EAQ85993.1 - 0.00049 18.0 0.0 0.0098 13.7 0.0 2.3 2 1 0 2 2 2 1 IKI3 family Nucleoporin_N PF08801.6 EAQ85993.1 - 0.0014 17.5 2.8 8.1 5.0 1.4 4.6 1 1 0 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EAQ85993.1 - 0.032 12.5 0.0 5.2 5.2 0.0 3.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain Utp13 PF08625.6 EAQ85993.1 - 0.094 12.3 0.1 0.23 11.0 0.1 1.8 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Septin PF00735.13 EAQ85994.1 - 7.2e-117 389.3 0.4 1.1e-116 388.8 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EAQ85994.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAQ85994.1 - 3.2e-06 26.7 0.7 5.7e-05 22.6 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EAQ85994.1 - 1.1e-05 24.7 0.0 2.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EAQ85994.1 - 0.0023 18.4 0.1 0.0081 16.6 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EAQ85994.1 - 0.0032 17.0 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ85994.1 - 0.0037 17.4 0.3 0.013 15.6 0.0 2.1 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EAQ85994.1 - 0.0057 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 EAQ85994.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EAQ85994.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EAQ85994.1 - 0.012 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EAQ85994.1 - 0.017 14.5 0.6 0.054 12.8 0.4 1.9 2 1 0 2 2 2 0 Ras family T2SE PF00437.15 EAQ85994.1 - 0.032 13.1 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EAQ85994.1 - 0.036 12.8 1.8 0.92 8.2 0.0 3.0 3 0 0 3 3 3 0 ArgK protein ABC_tran PF00005.22 EAQ85994.1 - 0.041 14.1 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EAQ85994.1 - 0.042 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EAQ85994.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EAQ85994.1 - 0.09 12.7 2.7 0.35 10.8 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EAQ85994.1 - 0.097 12.4 7.0 0.68 9.7 0.1 3.0 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 EAQ85994.1 - 0.098 12.1 0.9 2.8 7.4 0.2 2.6 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EAQ85994.1 - 0.1 12.8 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Ribosomal_L6e PF01159.14 EAQ85994.1 - 0.13 12.5 4.8 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e DUF2968 PF11180.3 EAQ85994.1 - 0.13 11.6 6.4 0.36 10.1 4.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) KAP_NTPase PF07693.9 EAQ85994.1 - 0.17 10.8 2.6 0.33 9.8 1.8 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Atg14 PF10186.4 EAQ85994.1 - 0.55 9.1 6.6 1.4 7.7 4.6 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 EAQ85994.1 - 1.1 9.3 7.3 1.1 9.3 2.6 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Myc-LZ PF02344.10 EAQ85994.1 - 2.5 7.8 11.4 1.4 8.6 3.1 3.1 2 1 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 EAQ85994.1 - 5.6 7.2 20.4 1.3e+02 2.7 14.1 2.2 1 1 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.4 EAQ85995.1 - 2.5e-42 144.2 0.3 4.4e-42 143.3 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EAQ85995.1 - 3.1e-10 39.7 0.0 9.3e-09 34.9 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EAQ85995.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zip PF02535.17 EAQ85995.1 - 0.035 13.0 0.4 0.046 12.7 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HATPase_c_2 PF13581.1 EAQ85995.1 - 0.12 12.1 0.0 0.55 10.0 0.0 2.2 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 EAQ85996.1 - 1.4e-77 260.3 0.3 1.5e-75 253.6 0.1 2.7 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EAQ85996.1 - 6e-73 244.8 6.8 5e-70 235.2 0.3 4.3 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EAQ85996.1 - 2.4e-47 161.3 1.3 2.5e-38 131.7 0.0 2.7 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ85996.1 - 5.7e-21 75.2 0.6 1.9e-13 50.5 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EAQ85996.1 - 5.6e-13 49.1 2.8 3.8e-12 46.4 0.1 3.3 3 1 0 3 3 3 1 MATH domain Tim17 PF02466.14 EAQ85997.1 - 1.4e-50 170.5 11.3 1.4e-50 170.5 7.8 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 EAQ85997.1 - 0.7 9.8 0.0 0.7 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Glyco_hydro_16 PF00722.16 EAQ85998.1 - 6.2e-09 35.4 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SP_C-Propep PF08999.5 EAQ85998.1 - 0.0097 15.3 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide EphA2_TM PF14575.1 EAQ85998.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3753 PF12575.3 EAQ85998.1 - 0.18 11.6 0.6 0.32 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) VirB8 PF04335.8 EAQ85998.1 - 5.9 6.4 5.5 14 5.1 2.5 2.0 2 0 0 2 2 2 0 VirB8 protein SKIP_SNW PF02731.10 EAQ85999.1 - 3.8e-66 221.3 5.7 3.8e-66 221.3 3.9 2.4 3 0 0 3 3 3 1 SKIP/SNW domain Corona_nucleoca PF00937.13 EAQ85999.1 - 2.5 6.9 19.1 1.1 8.1 6.9 3.1 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein EMP24_GP25L PF01105.19 EAQ86000.1 - 1.3e-46 158.6 3.5 1.5e-46 158.4 2.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoD PF09423.5 EAQ86001.1 - 2.5e-67 227.4 0.0 3.2e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.11 EAQ86001.1 - 1.9e-36 126.0 0.0 3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EAQ86001.1 - 0.067 12.0 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 CsiD adh_short_C2 PF13561.1 EAQ86002.1 - 7.4e-23 81.5 0.1 1.3e-22 80.8 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ86002.1 - 2.6e-20 73.0 1.2 1.1e-19 71.0 0.8 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ86002.1 - 2.1e-07 30.8 0.2 1e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_Gly3P_dh_N PF01210.18 EAQ86002.1 - 0.0002 21.1 0.2 0.00042 20.0 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EAQ86002.1 - 0.00066 19.3 0.2 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ86002.1 - 0.001 19.4 0.5 0.0019 18.5 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EAQ86002.1 - 0.0015 17.7 0.1 0.0044 16.2 0.0 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.20 EAQ86002.1 - 0.0046 16.2 0.1 0.006 15.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.15 EAQ86002.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Metallophos PF00149.23 EAQ86003.1 - 6.1e-42 143.2 1.4 9.2e-42 142.7 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L18e PF00828.14 EAQ86004.1 - 5.4e-32 110.8 0.0 7.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HA2 PF04408.18 EAQ86005.1 - 3.7e-18 65.4 0.0 1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAQ86005.1 - 1.8e-13 50.1 0.0 8.5e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EAQ86005.1 - 6.7e-11 42.0 0.0 1.8e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EAQ86005.1 - 5.8e-09 35.6 0.0 4.1e-08 32.9 0.1 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAQ86005.1 - 1.4e-05 25.1 0.2 5.6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EAQ86005.1 - 0.00054 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EAQ86005.1 - 0.0019 18.0 0.0 0.055 13.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EAQ86005.1 - 0.003 16.8 0.1 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EAQ86005.1 - 0.0048 15.8 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EAQ86005.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EAQ86005.1 - 0.042 14.1 5.3 0.077 13.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Med6 PF04934.9 EAQ86006.1 - 2.2e-14 53.1 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.4 EAQ86007.1 - 1.4e-29 101.9 3.2 1.4e-29 101.9 2.2 2.7 2 1 0 2 2 2 1 Kinase phosphorylation protein DUF3684 PF12449.3 EAQ86008.1 - 0 1383.2 0.0 0 1375.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EAQ86008.1 - 3.4e-06 26.7 0.0 7.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAQ86008.1 - 0.005 16.5 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.14 EAQ86009.1 - 2.2e-51 173.5 0.0 3.7e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ86009.1 - 1e-15 57.3 0.0 1.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAQ86009.1 - 0.0002 21.2 0.0 0.00068 19.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.1 EAQ86010.1 - 2.7e-62 210.7 36.7 3.7e-62 210.2 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAQ86010.1 - 3.3e-30 104.8 24.0 3.3e-30 104.8 16.6 2.0 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.17 EAQ86011.1 - 1.2e-52 178.7 0.0 6.7e-17 60.7 0.0 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EAQ86011.1 - 3.3e-40 137.3 0.0 7.4e-40 136.2 0.0 1.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EAQ86011.1 - 1.2e-29 103.2 0.0 1.2e-21 76.8 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EAQ86011.1 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EAQ86011.1 - 0.0048 15.7 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EAQ86011.1 - 0.045 12.8 0.0 5 6.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain UvrD_C_2 PF13538.1 EAQ86012.1 - 0.00022 21.2 0.0 0.0027 17.8 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ86012.1 - 0.00029 18.7 0.0 0.00041 18.2 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EAQ86012.1 - 0.00034 19.6 0.0 0.00048 19.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase EF-hand_1 PF00036.27 EAQ86013.1 - 5.6e-27 90.9 10.5 4.1e-07 28.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAQ86013.1 - 6.8e-24 83.7 2.3 1.3e-12 47.6 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAQ86013.1 - 4.6e-20 69.6 5.1 4.7e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAQ86013.1 - 3.3e-19 67.2 11.4 1.6e-06 27.1 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EAQ86013.1 - 7.1e-15 54.3 13.7 5.6e-05 22.6 0.7 4.7 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAQ86013.1 - 1.3e-06 28.3 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EAQ86013.1 - 5e-06 26.2 8.4 0.016 14.9 0.2 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EAQ86013.1 - 0.0088 15.9 0.0 0.33 10.8 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.1 EAQ86013.1 - 0.17 12.2 2.5 9.3 6.6 0.3 2.8 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAQ86013.1 - 5.6 6.7 6.2 7.7 6.3 0.1 2.8 3 0 0 3 3 3 0 FG-GAP repeat EPL1 PF10513.4 EAQ86014.1 - 1.7e-13 51.1 11.1 5.4e-08 33.2 0.1 3.7 2 2 1 3 3 3 2 Enhancer of polycomb-like DUF3952 PF13130.1 EAQ86014.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3952) adh_short PF00106.20 EAQ86014.1 - 0.19 11.6 0.3 5.2 6.9 0.0 2.6 3 0 0 3 3 3 0 short chain dehydrogenase Peptidase_M22 PF00814.20 EAQ86015.1 - 2.9e-83 279.4 0.0 3.5e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 EAQ86015.1 - 0.083 12.4 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein AMPKBI PF04739.10 EAQ86016.1 - 5.4e-31 106.4 2.2 5.4e-31 106.4 1.5 1.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Spt4 PF06093.8 EAQ86017.1 - 2e-33 114.0 0.2 2.4e-33 113.8 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Kin17_mid PF10357.4 EAQ86018.1 - 1.4e-47 160.4 1.9 1.4e-47 160.4 1.3 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EAQ86018.1 - 2.4e-05 24.3 3.8 4.1e-05 23.6 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAQ86018.1 - 0.00013 21.9 4.2 0.00027 20.9 2.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAQ86018.1 - 0.001 19.1 1.2 0.0023 18.0 0.8 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_7 PF03492.10 EAQ86018.1 - 0.057 12.1 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase ABM PF03992.11 EAQ86018.1 - 0.74 9.8 3.8 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase zf-C2H2_4 PF13894.1 EAQ86018.1 - 0.84 10.1 4.0 2.3 8.7 2.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger AA_kinase PF00696.23 EAQ86019.1 - 1.1e-35 123.3 0.0 1.8e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EAQ86019.1 - 1.2e-15 56.5 1.7 1.6e-09 37.0 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EAQ86019.1 - 1.3e-13 50.1 4.3 4.4e-10 38.9 0.1 2.5 2 0 0 2 2 2 2 ACT domain ABC_tran PF00005.22 EAQ86020.1 - 6.9e-14 52.3 0.0 2.1e-13 50.7 0.0 1.8 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EAQ86020.1 - 0.00068 18.9 0.0 0.00096 18.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EAQ86020.1 - 0.0019 16.8 0.2 0.0023 16.6 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EAQ86020.1 - 0.013 15.3 4.0 0.089 12.7 1.5 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EAQ86020.1 - 0.036 14.0 0.5 0.093 12.6 0.0 1.8 1 1 0 2 2 2 0 AAA domain CTD_bind PF04818.8 EAQ86021.1 - 3.2e-15 56.1 0.2 2.3e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EAQ86022.1 - 2e-77 260.1 4.4 2.3e-77 259.9 3.0 1.0 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 EAQ86022.1 - 0.4 10.4 9.5 0.61 9.8 6.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Cnl2_NKP2 PF09447.5 EAQ86022.1 - 1.4 8.6 5.1 2.5 7.8 3.5 1.5 1 0 0 1 1 1 0 Cnl2/NKP2 family protein SNARE PF05739.14 EAQ86023.1 - 5.7e-20 70.7 3.9 8.5e-20 70.2 1.6 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EAQ86023.1 - 9.4e-14 51.4 3.4 1.9e-12 47.2 0.1 2.6 2 0 0 2 2 2 1 Syntaxin vMSA PF00695.14 EAQ86023.1 - 0.0025 17.0 0.3 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Major surface antigen from hepadnavirus MCPsignal PF00015.16 EAQ86023.1 - 0.0056 16.2 8.1 0.014 14.9 1.1 2.6 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TMPIT PF07851.8 EAQ86023.1 - 0.021 13.9 2.1 0.052 12.6 1.5 1.6 1 0 0 1 1 1 0 TMPIT-like protein DNA_repr_REX1B PF14966.1 EAQ86023.1 - 0.36 11.2 0.1 0.36 11.2 0.1 3.1 3 1 1 4 4 4 0 DNA repair REX1-B EF-hand_1 PF00036.27 EAQ86024.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAQ86024.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAQ86024.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EAQ86024.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAQ86024.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EAQ86024.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAQ86024.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAQ86024.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EAQ86024.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EAQ86024.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EAQ86024.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EAQ86024.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 EAQ86024.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EAQ86024.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EAQ86024.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 EAQ86024.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EAQ86024.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EAQ86024.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 EAQ86024.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain Adaptin_N PF01602.15 EAQ86025.1 - 1.1e-136 456.2 2.8 1.4e-136 455.8 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EAQ86025.1 - 1.1e-05 25.6 3.4 0.18 12.1 0.1 3.9 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EAQ86025.1 - 0.00016 21.6 5.6 0.0019 18.1 0.2 3.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EAQ86025.1 - 0.00095 19.0 2.2 11 6.3 0.0 5.3 4 1 1 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EAQ86025.1 - 0.0036 17.7 1.7 32 5.1 0.0 5.1 4 1 1 5 5 5 0 HEAT-like repeat Arm PF00514.18 EAQ86025.1 - 0.017 14.9 0.1 48 3.9 0.1 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EAQ86025.1 - 0.032 13.8 0.0 0.44 10.2 0.0 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis G-patch_2 PF12656.2 EAQ86025.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site TIP120 PF08623.5 EAQ86025.1 - 0.13 11.8 0.1 0.13 11.8 0.1 3.0 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) DUF947 PF06102.7 EAQ86026.1 - 4.5e-59 199.0 20.1 8.7e-59 198.1 13.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF947) ABC1 PF03109.11 EAQ86027.1 - 6.6e-33 113.2 0.0 1.3e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EAQ86027.1 - 0.16 11.0 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain DUF4614 PF15391.1 EAQ86027.1 - 2.9 7.6 7.6 0.27 10.9 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Es2 PF09751.4 EAQ86028.1 - 1.4e-97 327.8 0.3 1.6e-96 324.2 0.2 1.9 1 1 0 1 1 1 1 Nuclear protein Es2 Hus1 PF04005.7 EAQ86029.1 - 1.1e-88 296.9 0.0 1.6e-88 296.4 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.1 EAQ86029.1 - 3.4e-09 36.3 1.7 3.4e-09 36.3 1.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EAQ86029.1 - 3.3e-06 27.1 0.3 6.9e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAQ86029.1 - 4e-06 26.3 1.4 4e-06 26.3 1.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ86029.1 - 7.2e-06 25.6 1.5 2.3e-05 24.0 1.0 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAQ86029.1 - 1.1e-05 24.9 1.7 2.6e-05 23.8 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ86029.1 - 4.3e-05 23.4 0.9 4.3e-05 23.4 0.6 2.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ86029.1 - 0.0019 18.0 0.4 0.0019 18.0 0.3 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EAQ86029.1 - 0.013 15.3 0.3 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EAQ86029.1 - 0.22 11.1 1.9 0.55 9.8 1.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EAQ86029.1 - 0.22 11.2 5.2 0.23 11.1 0.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Sec16_C PF12931.2 EAQ86030.1 - 7.8e-94 314.5 0.0 1e-93 314.1 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EAQ86030.1 - 2.8e-23 82.1 0.0 5.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hydrolase PF00702.21 EAQ86031.1 - 3.4e-16 60.2 0.0 1e-15 58.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAQ86031.1 - 3e-14 52.6 0.0 8.1e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EAQ86031.1 - 2.1e-10 41.0 0.0 5.2e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ86031.1 - 0.00011 22.0 0.0 0.00054 19.8 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAQ86031.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_S9 PF00380.14 EAQ86035.1 - 1.1e-36 125.7 0.2 1.9e-36 124.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EAQ86036.1 - 1.7e-42 143.5 0.2 4e-42 142.2 0.1 1.7 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EAQ86036.1 - 6.8e-14 51.6 0.0 1.4e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ86036.1 - 1.2e-12 47.5 0.0 3.1e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAQ86036.1 - 3.1e-10 40.0 0.0 1.3e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ86036.1 - 2.4e-09 37.2 0.0 8.8e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EAQ86036.1 - 9e-06 26.0 0.0 1.7e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAQ86036.1 - 0.00047 20.1 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 EAQ86037.1 - 2.4e-14 53.3 0.0 5.1e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_capsid PF03035.9 EAQ86037.1 - 0.21 11.3 5.2 5.4 6.7 0.3 3.0 2 1 1 3 3 3 0 Calicivirus putative RNA polymerase/capsid protein DUF3455 PF11937.3 EAQ86038.1 - 2.8e-34 118.6 0.0 3.5e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 EAQ86038.1 - 0.00074 19.3 3.4 0.0017 18.1 1.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) CASP_C PF08172.7 EAQ86039.1 - 1.6e-45 155.0 14.2 3.1e-36 124.6 0.0 3.5 2 1 1 3 3 3 2 CASP C terminal Tropomyosin_1 PF12718.2 EAQ86039.1 - 3.7e-05 23.5 43.6 0.024 14.4 12.0 4.5 3 1 1 4 4 4 4 Tropomyosin like ATG16 PF08614.6 EAQ86039.1 - 0.078 12.7 41.0 0.67 9.7 6.3 3.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF4349 PF14257.1 EAQ86039.1 - 0.27 10.4 21.4 0.046 12.9 3.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) DivIVA PF05103.8 EAQ86039.1 - 1.6 8.7 30.7 1.1 9.2 1.7 3.9 3 1 0 3 3 3 0 DivIVA protein DUF1192 PF06698.6 EAQ86039.1 - 4.4 7.1 12.7 0.12 12.1 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FUSC PF04632.7 EAQ86039.1 - 7.7 4.8 16.5 0.012 14.0 0.6 2.5 3 0 0 3 3 3 0 Fusaric acid resistance protein family DUF4404 PF14357.1 EAQ86039.1 - 9.2 6.7 22.3 2.8 8.4 1.6 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Vps39_2 PF10367.4 EAQ86040.1 - 9.4e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Dicty_CAR PF05462.6 EAQ86041.1 - 2.3e-06 26.7 11.6 2.3e-06 26.7 8.0 2.1 2 1 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EAQ86041.1 - 0.00018 21.1 10.5 0.00034 20.2 7.3 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Mucin PF01456.12 EAQ86041.1 - 7 6.4 20.7 20 4.9 14.4 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Xan_ur_permease PF00860.15 EAQ86043.1 - 5.8e-26 90.8 27.2 2.9e-24 85.3 18.8 2.2 1 1 0 1 1 1 1 Permease family Peptidase_C12 PF01088.16 EAQ86044.1 - 1.7e-67 226.7 0.0 2.1e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosomal_L22 PF00237.14 EAQ86045.1 - 4e-34 116.7 0.0 5.7e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.12 EAQ86046.1 - 3.7e-96 320.4 0.0 4.6e-96 320.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EAQ86046.1 - 2.4e-06 27.2 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EAQ86046.1 - 0.0077 15.7 0.1 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EAQ86046.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 EAQ86049.1 - 0.00039 20.5 13.4 0.16 12.4 0.0 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ86049.1 - 0.003 17.8 16.6 1.2 9.6 0.5 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EAQ86049.1 - 0.0084 15.9 1.3 0.084 12.8 0.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 EAQ86049.1 - 0.17 10.3 0.2 0.48 8.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 EAQ86049.1 - 0.61 10.4 11.7 12 6.4 0.8 3.9 3 1 0 3 3 3 0 Zinc-finger double domain Methyltransf_16 PF10294.4 EAQ86050.1 - 3.3e-11 42.9 0.0 4.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EAQ86050.1 - 0.00098 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EAQ86050.1 - 0.019 15.5 0.0 0.035 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain zf-rbx1 PF12678.2 EAQ86052.1 - 1.2e-11 44.5 1.5 2.2e-11 43.6 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EAQ86052.1 - 2.4e-11 43.2 5.3 4.2e-11 42.4 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAQ86052.1 - 2.3e-07 30.3 4.0 6.3e-07 28.9 2.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ86052.1 - 3.1e-06 26.7 2.5 5.6e-06 25.9 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAQ86052.1 - 4.7e-06 26.5 3.0 1.4e-05 25.0 2.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ86052.1 - 6.1e-06 25.8 3.1 1e-05 25.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAQ86052.1 - 0.00073 19.3 0.5 0.0015 18.3 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EAQ86052.1 - 0.0029 17.2 2.0 0.0074 15.9 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EAQ86052.1 - 0.008 15.7 0.3 0.017 14.6 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EAQ86052.1 - 0.51 9.9 2.4 1.1 8.8 1.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EAQ86052.1 - 5.9 6.9 5.2 5.5 7.0 2.1 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain TPR_11 PF13414.1 EAQ86054.1 - 8.2e-10 38.1 0.8 2.9e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EAQ86054.1 - 0.00059 19.5 4.0 0.18 11.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ86054.1 - 0.0021 18.1 2.1 0.44 10.7 0.4 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EAQ86054.1 - 0.0023 17.4 2.6 0.099 12.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ86054.1 - 0.013 15.2 0.2 0.13 12.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ86054.1 - 0.015 15.2 0.3 0.19 11.6 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86054.1 - 0.066 13.5 0.4 0.16 12.3 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86054.1 - 2.8 8.7 11.0 1.7 9.4 1.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Atg14 PF10186.4 EAQ86055.1 - 3.6 6.4 7.1 0.32 9.8 1.0 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EAQ86055.1 - 4.6 6.9 5.4 16 5.2 0.1 3.3 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 FAD_binding_1 PF00667.15 EAQ86057.1 - 1.9e-43 148.4 0.0 2.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EAQ86057.1 - 6.5e-10 39.5 0.0 1.5e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.19 EAQ86058.1 - 1.2e-12 47.9 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PS_Dcarbxylase PF02666.10 EAQ86059.1 - 1.3e-63 213.9 0.0 5.9e-62 208.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EAQ86059.1 - 0.029 14.0 0.1 0.056 13.1 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like DUF2741 PF10890.3 EAQ86059.1 - 0.14 12.3 0.1 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2741) ubiquitin PF00240.18 EAQ86060.1 - 3.4e-06 26.3 0.0 8.9e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EAQ86060.1 - 0.00034 20.7 1.6 0.00068 19.7 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Neur_chan_memb PF02932.11 EAQ86060.1 - 0.011 15.6 5.8 0.46 10.3 0.3 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 EAQ86060.1 - 0.12 12.4 0.0 0.12 12.4 0.0 4.9 3 1 2 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRP-S23 PF10484.4 EAQ86060.1 - 4.5 7.1 7.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal protein S23 adh_short PF00106.20 EAQ86061.1 - 3.7e-23 82.2 9.1 5.7e-23 81.6 6.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ86061.1 - 2.4e-20 73.3 0.1 3e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ86061.1 - 3.5e-12 46.3 4.7 5.8e-12 45.6 3.3 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ86061.1 - 0.19 11.5 2.0 0.31 10.8 0.3 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase N2227 PF07942.7 EAQ86062.1 - 3.1e-99 331.3 0.0 3.8e-99 331.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EAQ86062.1 - 3.5e-08 33.3 0.0 5.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ86062.1 - 0.0022 18.4 0.0 0.01 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ86062.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ86062.1 - 0.023 15.2 0.0 0.13 12.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ86062.1 - 0.049 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EAQ86062.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ86062.1 - 0.12 11.9 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HsdM_N PF12161.3 EAQ86062.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 HsdM N-terminal domain HEAT_EZ PF13513.1 EAQ86064.1 - 1.3e-26 92.2 9.6 3e-14 53.0 0.0 11.1 9 2 2 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.1 EAQ86064.1 - 1.2e-23 83.1 0.2 7.1e-07 29.4 0.0 8.0 5 3 5 10 10 9 7 HEAT repeats HEAT PF02985.17 EAQ86064.1 - 2.7e-23 79.8 17.4 8.3e-06 25.4 0.0 10.1 12 0 0 12 12 10 5 HEAT repeat MMS19_C PF12460.3 EAQ86064.1 - 5.6e-13 48.3 1.7 0.0004 19.2 0.0 4.5 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 EAQ86064.1 - 6.8e-09 36.0 0.1 0.1 13.0 0.0 6.6 5 2 3 8 8 8 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EAQ86064.1 - 1.2e-06 28.2 2.5 0.00012 21.9 0.2 4.5 3 1 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EAQ86064.1 - 1.5e-05 24.8 0.1 0.67 9.7 0.0 5.2 5 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EAQ86064.1 - 2.1e-05 24.1 1.3 0.083 12.7 0.0 5.5 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EAQ86064.1 - 6.9e-05 22.3 0.1 7.5 5.8 0.0 6.6 6 2 1 7 7 7 1 CLASP N terminal HEAT_PBS PF03130.11 EAQ86064.1 - 0.0039 17.5 1.3 2.8 8.6 0.0 4.9 4 0 0 4 4 2 1 PBS lyase HEAT-like repeat DUF3437 PF11919.3 EAQ86064.1 - 0.034 13.8 0.0 0.78 9.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) RIX1 PF08167.7 EAQ86064.1 - 0.058 13.0 0.0 10 5.7 0.0 3.9 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Zn_clus PF00172.13 EAQ86067.1 - 6.8e-08 32.2 11.8 1e-07 31.6 8.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ86067.1 - 1e-05 24.3 0.5 1.5e-05 23.7 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain SPRY PF00622.23 EAQ86068.1 - 1.2e-15 57.6 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Zip PF02535.17 EAQ86069.1 - 0.12 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Exo_endo_phos PF03372.18 EAQ86071.1 - 4.1e-11 43.2 0.2 5.5e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sipho_Gp157 PF05565.6 EAQ86073.1 - 0.041 13.4 0.5 0.11 12.0 0.3 1.7 1 0 0 1 1 1 0 Siphovirus Gp157 SAP PF02037.22 EAQ86074.1 - 1.5e-13 49.8 0.0 2.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EAQ86074.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 HeH/LEM domain DUF3439 PF11921.3 EAQ86074.1 - 0.84 9.3 5.6 1.6 8.4 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mitofilin PF09731.4 EAQ86074.1 - 1.5 7.3 14.9 1.9 7.0 10.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Methyltransf_11 PF08241.7 EAQ86076.1 - 0.05 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ86076.1 - 0.84 8.6 0.0 1.3 8.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Aconitase PF00330.15 EAQ86077.1 - 1e-35 123.1 5.9 6e-16 57.9 0.3 5.0 1 1 3 4 4 4 4 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAQ86077.1 - 2.6e-16 59.9 0.0 4.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Metallophos PF00149.23 EAQ86078.1 - 2.7e-15 56.2 0.2 6.1e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_4 PF01565.18 EAQ86080.1 - 5.3e-19 68.0 4.9 6.1e-19 67.8 1.3 2.4 2 0 0 2 2 2 1 FAD binding domain GST_N_3 PF13417.1 EAQ86081.1 - 7.1e-14 51.8 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAQ86081.1 - 1.3e-10 41.2 0.0 3.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ86081.1 - 1.9e-10 40.5 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAQ86081.1 - 3.2e-10 39.8 0.0 7.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ86081.1 - 1.9e-09 37.2 0.0 4.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ86081.1 - 1.7e-08 34.8 0.3 2.9e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EAQ86081.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 MetRS-N binding domain zf-CCHC PF00098.18 EAQ86082.1 - 1.5e-11 43.6 9.7 1.9e-05 24.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EAQ86082.1 - 8.8e-09 34.8 0.1 1.7e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EAQ86082.1 - 1.5e-06 27.8 6.8 0.00037 20.1 2.6 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EAQ86082.1 - 4.8e-06 26.0 0.2 1.1e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EAQ86082.1 - 6.1e-05 22.6 5.9 0.025 14.2 0.1 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EAQ86082.1 - 0.0013 18.3 6.0 0.3 10.7 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EAQ86082.1 - 0.11 11.9 0.2 0.11 11.9 0.1 3.7 2 1 1 3 3 3 0 Zinc knuckle Peptidase_M28 PF04389.12 EAQ86083.1 - 1.4e-18 67.3 0.0 2.5e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PAN_4 PF14295.1 EAQ86084.1 - 0.2 11.4 4.3 0.39 10.4 3.0 1.7 1 1 0 1 1 1 0 PAN domain Med11 PF10280.4 EAQ86085.1 - 1.9e-37 127.9 0.0 2.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF3210 PF11489.3 EAQ86085.1 - 0.13 10.9 3.5 0.51 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3210) WD40 PF00400.27 EAQ86086.1 - 2e-50 166.9 20.9 4.1e-09 35.9 0.7 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EAQ86086.1 - 6.2e-46 156.0 0.0 9.7e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 EAQ86086.1 - 1.4e-06 28.2 0.1 0.00032 20.4 0.0 3.4 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EAQ86086.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EAQ86086.1 - 0.0027 15.9 0.6 7.5 4.5 0.0 3.4 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ86086.1 - 0.017 13.8 0.1 2.8 6.5 0.0 3.2 2 2 0 3 3 3 0 Nup133 N terminal like IKI3 PF04762.7 EAQ86086.1 - 0.053 11.3 0.1 0.13 10.0 0.0 1.5 1 1 0 1 1 1 0 IKI3 family Vps5 PF09325.5 EAQ86087.1 - 2.1e-86 289.0 4.6 3.6e-86 288.2 3.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EAQ86087.1 - 3.1e-24 84.9 0.0 6.7e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 EAQ86087.1 - 0.002 17.0 2.0 0.005 15.8 1.5 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.4 EAQ86087.1 - 0.018 14.3 1.1 0.17 11.1 0.7 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein BAR PF03114.13 EAQ86087.1 - 0.026 14.0 5.9 0.043 13.3 4.1 1.3 1 0 0 1 1 1 0 BAR domain Ribosomal_L31 PF01197.13 EAQ86088.1 - 0.0053 16.7 0.1 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L31 Flavin_Reduct PF01613.13 EAQ86089.1 - 1.5e-33 115.8 0.0 2.1e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain FKBP_C PF00254.23 EAQ86090.1 - 4.3e-34 116.4 0.0 4.9e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HSP90 PF00183.13 EAQ86092.1 - 1.6e-120 403.0 4.9 2e-120 402.7 3.4 1.0 1 0 0 1 1 1 1 Hsp90 protein LOH1CR12 PF10158.4 EAQ86092.1 - 0.013 15.2 0.3 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Tumour suppressor protein Peptidase_S10 PF00450.17 EAQ86092.1 - 0.062 12.4 0.1 0.15 11.1 0.0 1.5 1 1 0 1 1 1 0 Serine carboxypeptidase DUF1198 PF06711.6 EAQ86092.1 - 0.1 12.4 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) MBOAT PF03062.14 EAQ86094.1 - 6e-27 94.6 12.9 1.8e-26 93.0 9.0 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DnaJ PF00226.26 EAQ86095.1 - 4.3e-12 45.5 0.2 8.8e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EAQ86097.1 - 2.4e-13 49.9 1.2 1.4e-12 47.4 0.8 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAQ86097.1 - 3.7e-09 36.6 0.0 9.2e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EAQ86097.1 - 0.055 12.6 0.0 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF515 PF04415.7 EAQ86100.1 - 6.2 4.9 5.7 7.1 4.7 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AF-4 PF05110.8 EAQ86100.1 - 8.8 4.0 12.0 9.4 3.9 8.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_primase_lrg PF04104.9 EAQ86101.1 - 2.6e-71 239.9 0.0 3.7e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CLP_protease PF00574.18 EAQ86103.1 - 6.8e-52 175.7 0.7 8.2e-52 175.5 0.5 1.1 1 0 0 1 1 1 1 Clp protease ECH PF00378.15 EAQ86103.1 - 0.022 13.8 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Cas_Csm6 PF09659.5 EAQ86103.1 - 0.11 11.1 0.3 0.13 10.8 0.2 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) ILVD_EDD PF00920.16 EAQ86104.1 - 1.4e-210 700.1 0.1 1.7e-210 699.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.1 EAQ86104.1 - 0.081 12.5 1.6 0.76 9.4 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Kinesin PF00225.18 EAQ86106.1 - 2.1e-104 348.8 0.1 2.1e-104 348.8 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 EAQ86106.1 - 5.1e-05 21.9 43.9 0.00048 18.7 30.4 2.2 1 1 0 1 1 1 1 Weak chloroplast movement under blue light AAA_24 PF13479.1 EAQ86106.1 - 0.032 13.7 2.2 0.26 10.8 1.5 2.6 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EAQ86106.1 - 1.8 7.6 6.6 1.1 8.4 1.6 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein FAD_binding_3 PF01494.14 EAQ86107.1 - 4.7e-15 55.5 0.0 2.7e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Thioesterase PF00975.15 EAQ86108.1 - 1.8e-14 54.5 0.3 2.7e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EAQ86108.1 - 3.3e-09 36.9 3.3 3.8e-09 36.7 2.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ86108.1 - 0.00014 21.6 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAQ86108.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EAQ86108.1 - 0.055 13.0 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EAQ86108.1 - 0.067 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cerato-platanin PF07249.7 EAQ86110.1 - 5.6e-47 158.6 1.5 1.1e-46 157.7 1.0 1.4 1 0 0 1 1 1 1 Cerato-platanin DUF2835 PF11197.3 EAQ86110.1 - 0.18 11.6 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) Fungal_trans PF04082.13 EAQ86111.1 - 1.7e-10 40.2 2.7 8.4e-10 37.9 1.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ86111.1 - 4.4e-10 39.2 9.8 7.6e-10 38.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 EAQ86113.1 - 1.9e-15 57.4 1.6 9e-15 55.2 1.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EAQ86114.1 - 2.7e-08 33.2 0.3 4.7e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ86114.1 - 8.7e-06 25.3 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EAQ86114.1 - 1.6e-05 24.3 0.5 0.068 13.2 0.0 3.0 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EAQ86114.1 - 0.0034 17.3 1.8 0.36 11.2 0.0 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 EAQ86114.1 - 0.079 13.0 0.1 10 6.5 0.1 2.8 3 0 0 3 3 3 0 Leucine Rich repeat Methyltransf_25 PF13649.1 EAQ86116.1 - 5.3e-10 39.5 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ86116.1 - 2.5e-09 37.5 0.0 5.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ86116.1 - 1.3e-08 35.3 0.0 2.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ86116.1 - 9.9e-08 31.7 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ86116.1 - 2.2e-06 27.4 0.0 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ86116.1 - 3e-06 27.2 0.0 1.5e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ86116.1 - 5e-06 26.9 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ86116.1 - 1.2e-05 24.5 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3735 PF12537.3 EAQ86116.1 - 0.056 13.5 0.1 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) MTS PF05175.9 EAQ86116.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Complex1_LYR PF05347.10 EAQ86117.1 - 0.0015 18.2 0.1 0.0039 16.9 0.0 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ86117.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like 4HBT_2 PF13279.1 EAQ86118.1 - 1.7e-13 51.0 0.1 2.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Osmo_CC PF08946.5 EAQ86119.1 - 1.2 9.2 5.5 0.92 9.5 0.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF3287 PF11690.3 EAQ86119.1 - 2 8.5 6.4 0.48 10.5 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) CFEM PF05730.6 EAQ86120.1 - 1e-12 47.6 8.8 1.5e-12 47.1 6.1 1.3 1 0 0 1 1 1 1 CFEM domain NAD_kinase PF01513.16 EAQ86121.1 - 9.9e-48 162.3 0.0 6.8e-47 159.6 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EAQ86122.1 - 1.4e-24 86.0 0.0 1.9e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TauD PF02668.11 EAQ86124.1 - 1.2e-22 80.8 0.0 1.8e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EAQ86124.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 CsiD Sua5_yciO_yrdC PF01300.13 EAQ86125.1 - 5.9e-14 51.7 0.0 7.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination RVT_1 PF00078.22 EAQ86126.1 - 3.9e-16 59.0 0.0 2.6e-10 40.0 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) priB_priC PF07445.7 EAQ86126.1 - 1.5 8.2 8.6 0.37 10.2 2.8 2.2 2 0 0 2 2 2 0 Primosomal replication protein priB and priC Zn_clus PF00172.13 EAQ86127.1 - 0.13 12.2 5.7 0.27 11.1 3.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 EAQ86128.1 - 2.3e-12 46.3 5.4 4.1e-09 35.9 2.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAQ86128.1 - 3.3e-09 35.9 9.2 0.00053 19.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ86128.1 - 2e-06 27.1 3.1 0.074 12.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ86128.1 - 3.2e-06 26.9 5.4 5.1e-05 23.1 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86128.1 - 7e-05 23.3 12.0 0.0052 17.4 0.3 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ86128.1 - 0.01 15.5 0.9 14 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86128.1 - 0.011 15.9 0.5 0.058 13.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ86128.1 - 0.025 15.1 0.3 0.025 15.1 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ86128.1 - 0.052 13.4 6.9 1.5 8.7 1.2 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ86128.1 - 0.073 13.5 1.4 2.5 8.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ86128.1 - 0.12 12.8 5.5 0.24 11.9 1.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2046 PF09755.4 EAQ86129.1 - 0.0074 15.2 0.2 0.008 15.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF89 PF01937.14 EAQ86132.1 - 1.6e-121 405.4 0.0 2e-121 405.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lipase_3 PF01764.20 EAQ86133.1 - 4.8e-20 71.6 0.0 1.2e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Gate PF07670.9 EAQ86133.1 - 0.0042 16.9 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoside recognition SNARE PF05739.14 EAQ86133.1 - 0.0056 16.3 0.8 0.77 9.4 0.0 2.4 2 0 0 2 2 2 2 SNARE domain RAI16-like PF10257.4 EAQ86134.1 - 2.7e-75 253.5 2.9 4.1e-75 252.9 2.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Glyco_hydro_10 PF00331.15 EAQ86135.1 - 2.6e-52 177.8 0.0 4.2e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 FAD_binding_4 PF01565.18 EAQ86136.1 - 2.9e-28 98.0 7.0 2.9e-28 98.0 4.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAQ86136.1 - 7.4e-13 48.1 0.2 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cutinase PF01083.17 EAQ86137.1 - 3.4e-54 183.2 0.9 4.3e-54 182.9 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EAQ86137.1 - 0.00093 18.6 0.1 0.0014 18.1 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EAQ86137.1 - 0.0011 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EAQ86137.1 - 0.0018 18.0 0.6 0.0035 17.1 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EAQ86140.1 - 4e-45 154.1 0.0 5.2e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EAQ86141.1 - 4.3e-66 222.9 4.5 5.5e-66 222.5 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GFA PF04828.9 EAQ86142.1 - 1.1e-09 38.0 2.7 3.7e-08 33.1 0.0 2.5 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ytp1 PF10355.4 EAQ86143.1 - 9.8e-84 280.7 16.3 9.8e-84 280.7 11.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EAQ86143.1 - 2e-33 114.1 1.4 2e-33 114.1 1.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) DUF4225 PF13988.1 EAQ86143.1 - 1.6 8.1 3.5 0.43 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Peptidase_M20 PF01546.23 EAQ86144.1 - 2.8e-08 33.4 0.3 4.1e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAQ86144.1 - 1.7e-05 24.5 0.0 6.5e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain GFO_IDH_MocA PF01408.17 EAQ86147.1 - 3.3e-24 85.6 0.0 5.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAQ86147.1 - 1.6e-11 43.9 0.1 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EAQ86147.1 - 0.00043 20.6 0.1 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EAQ86147.1 - 0.0083 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 EAQ86148.1 - 4.5e-24 84.4 1.6 8e-24 83.6 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 EAQ86149.1 - 2e-23 83.1 5.7 3.4e-23 82.4 3.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ86149.1 - 3.8e-16 59.2 3.3 7.8e-16 58.2 2.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ86149.1 - 2e-10 40.5 0.1 4.4e-10 39.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ86149.1 - 1.2e-07 30.9 0.0 1.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EAQ86149.1 - 2e-07 31.0 0.0 2.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EAQ86149.1 - 0.084 12.6 0.4 0.23 11.2 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EAQ86149.1 - 0.12 11.5 0.9 8.1 5.5 0.0 2.3 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EAQ86149.1 - 0.18 11.8 4.0 0.56 10.1 2.8 2.0 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EAQ86149.1 - 0.2 11.7 3.9 1.1 9.3 0.4 2.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_5 PF12695.2 EAQ86150.1 - 4.4e-10 39.4 0.3 6.5e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EAQ86150.1 - 7.6e-07 27.7 0.0 0.00016 20.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EAQ86150.1 - 0.00012 22.0 0.7 0.00021 21.2 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ86150.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PGM_PMM_I PF02878.11 EAQ86150.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Abhydrolase_6 PF12697.2 EAQ86152.1 - 2.4e-06 27.5 0.2 4.4e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EAQ86152.1 - 1.4e-05 24.4 0.0 2.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAQ86152.1 - 0.0024 17.6 0.0 0.007 16.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ86152.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 EAQ86152.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GAS PF13851.1 EAQ86153.1 - 0.053 12.7 19.9 0.026 13.7 10.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 EAQ86153.1 - 0.063 13.1 15.5 0.5 10.2 6.6 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein VSG_B PF13206.1 EAQ86153.1 - 0.071 12.2 15.6 0.1 11.7 10.8 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1664 PF07889.7 EAQ86153.1 - 0.12 12.1 14.8 0.63 9.8 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 EAQ86153.1 - 0.69 9.6 17.5 0.35 10.6 7.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 EAQ86153.1 - 0.8 8.9 11.0 0.25 10.5 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CENP-H PF05837.7 EAQ86153.1 - 1.3 9.2 16.7 0.52 10.4 8.2 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DivIVA PF05103.8 EAQ86153.1 - 2.2 8.3 25.0 3.2 7.8 1.5 2.5 2 1 0 2 2 2 0 DivIVA protein FTA4 PF13093.1 EAQ86153.1 - 2.8 7.3 15.0 4.9 6.5 10.4 1.4 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4407 PF14362.1 EAQ86153.1 - 3.3 6.5 18.0 8.1 5.2 12.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.1 EAQ86153.1 - 4.3 6.4 19.2 17 4.5 13.3 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 GlnE PF03710.10 EAQ86153.1 - 4.7 6.3 9.5 3.2 6.9 3.0 2.3 2 1 1 3 3 3 0 Glutamate-ammonia ligase adenylyltransferase PLRV_ORF5 PF01690.12 EAQ86153.1 - 4.8 6.2 10.9 5.8 5.9 7.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein IncA PF04156.9 EAQ86153.1 - 8.8 5.8 20.3 3.5 7.1 9.3 2.1 1 1 2 3 3 3 0 IncA protein Atg14 PF10186.4 EAQ86153.1 - 8.8 5.1 16.9 20 4.0 11.9 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EAQ86153.1 - 9.6 5.7 18.4 0.8 9.2 4.9 2.9 2 1 1 3 3 3 0 Septum formation initiator NACHT PF05729.7 EAQ86154.1 - 2.4e-06 27.3 0.0 1.4e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ86154.1 - 9.4e-05 22.4 0.0 0.00036 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EAQ86154.1 - 0.0018 18.4 0.0 0.0079 16.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.9 EAQ86154.1 - 0.0089 15.0 0.0 0.22 10.4 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain Noc2 PF03715.8 EAQ86154.1 - 0.031 13.1 0.1 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Noc2p family Sigma54_activ_2 PF14532.1 EAQ86154.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 EAQ86154.1 - 0.093 12.8 0.0 0.39 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain NPR3 PF03666.8 EAQ86154.1 - 0.22 10.0 0.0 0.35 9.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_hydro_72 PF03198.9 EAQ86156.1 - 3e-121 404.2 2.0 4.2e-121 403.7 1.4 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EAQ86156.1 - 3.7e-25 88.1 4.3 1.1e-24 86.7 3.0 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EAQ86156.1 - 1.1e-05 24.5 0.1 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Lipoxygenase PF00305.14 EAQ86157.1 - 2.2e-54 184.6 1.3 1.5e-53 181.8 0.9 1.9 1 1 0 1 1 1 1 Lipoxygenase Arylesterase PF01731.15 EAQ86158.1 - 0.06 13.3 0.0 0.86 9.6 0.0 2.6 2 1 0 2 2 2 0 Arylesterase Oxidored_FMN PF00724.15 EAQ86159.1 - 1.1e-10 41.1 0.0 0.00012 21.2 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Hint_2 PF13403.1 EAQ86160.1 - 4.2e-05 23.5 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Hint domain DUF1628 PF07790.6 EAQ86160.1 - 0.0048 17.6 0.2 0.0048 17.6 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1628) IncA PF04156.9 EAQ86160.1 - 0.21 11.1 9.5 0.49 9.9 6.6 1.6 1 0 0 1 1 1 0 IncA protein Tic20 PF09685.5 EAQ86160.1 - 0.36 10.8 10.2 0.86 9.6 7.1 1.5 1 0 0 1 1 1 0 Tic20-like protein Tetraspannin PF00335.15 EAQ86160.1 - 0.67 9.1 5.6 1.2 8.3 3.9 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF202 PF02656.10 EAQ86160.1 - 0.68 10.1 5.5 1.9 8.7 2.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DBINO PF13892.1 EAQ86161.1 - 1.9e-51 173.7 17.2 1.9e-51 173.7 11.9 4.6 4 1 1 5 5 5 1 DNA-binding domain SNF2_N PF00176.18 EAQ86161.1 - 3.7e-36 124.4 1.6 2.8e-20 72.3 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ86161.1 - 4.5e-16 58.4 0.0 1.3e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 EAQ86162.1 - 2.5e-34 118.5 0.0 1.7e-20 73.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EAQ86162.1 - 2.5e-21 75.2 2.0 2.5e-21 75.2 1.4 2.9 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 EAQ86162.1 - 7.3e-13 49.1 0.0 0.0028 17.6 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EAQ86162.1 - 1.8e-09 36.9 0.2 0.00087 18.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ86162.1 - 3.4e-08 34.0 4.1 0.029 14.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EAQ86162.1 - 2e-07 31.8 0.1 0.0036 18.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EAQ86162.1 - 1.7e-06 28.2 0.0 0.075 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAQ86162.1 - 2.7e-06 26.6 0.0 0.0044 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAQ86162.1 - 2.8e-06 27.6 0.1 0.027 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 EAQ86162.1 - 2.9e-06 26.6 0.0 0.34 10.1 0.0 3.7 4 0 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EAQ86162.1 - 3.5e-06 27.0 0.0 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EAQ86162.1 - 1.2e-05 25.2 0.0 0.099 12.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EAQ86162.1 - 1.5e-05 25.0 0.5 0.21 11.5 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EAQ86162.1 - 1.5e-05 24.4 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAQ86162.1 - 1.6e-05 24.8 0.0 0.22 11.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 EAQ86162.1 - 2.5e-05 24.7 0.0 0.056 13.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EAQ86162.1 - 3e-05 23.7 0.1 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EAQ86162.1 - 8.4e-05 22.7 0.0 0.35 11.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ86162.1 - 0.00015 21.5 0.2 0.57 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EAQ86162.1 - 0.00017 21.7 1.9 1.4 9.0 0.0 3.4 3 0 0 3 3 3 2 RNA helicase Arch_ATPase PF01637.13 EAQ86162.1 - 0.00026 20.7 0.1 0.24 11.0 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase AAA_10 PF12846.2 EAQ86162.1 - 0.00035 20.0 0.8 0.43 9.9 0.2 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_15 PF13175.1 EAQ86162.1 - 0.00055 19.1 0.0 0.15 11.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EAQ86162.1 - 0.00076 19.2 0.1 0.048 13.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EAQ86162.1 - 0.00077 19.3 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EAQ86162.1 - 0.0014 18.4 0.2 2.7 7.7 0.0 3.6 4 1 1 5 5 4 1 Dynamin family NB-ARC PF00931.17 EAQ86162.1 - 0.0044 15.9 0.0 1.2 7.9 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain DUF2813 PF11398.3 EAQ86162.1 - 0.0054 15.8 1.1 0.81 8.7 0.0 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF2813) DAP3 PF10236.4 EAQ86162.1 - 0.013 14.4 0.2 2.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 EAQ86162.1 - 0.025 14.0 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EAQ86162.1 - 0.025 14.2 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 EAQ86162.1 - 0.04 12.8 0.2 2.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EAQ86162.1 - 0.045 13.5 0.1 11 5.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EAQ86162.1 - 0.061 12.8 0.3 6.4 6.2 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EAQ86162.1 - 0.065 12.5 0.1 8.3 5.6 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B ArgK PF03308.11 EAQ86162.1 - 0.071 11.8 0.4 12 4.6 0.1 2.6 3 0 0 3 3 3 0 ArgK protein ABC_ATPase PF09818.4 EAQ86162.1 - 0.077 11.5 0.6 15 4.0 0.0 3.4 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DUF3584 PF12128.3 EAQ86162.1 - 0.19 9.0 1.4 0.35 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3353 PF11833.3 EAQ86163.1 - 0.0055 16.1 3.8 0.011 15.2 0.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3353) S1FA PF04689.8 EAQ86163.1 - 0.015 15.1 0.8 0.072 12.9 0.1 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA DUF2305 PF10230.4 EAQ86164.1 - 1.8e-54 184.9 0.0 2.6e-54 184.4 0.0 1.2 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EAQ86164.1 - 2.5e-06 27.5 1.7 4.1e-06 26.8 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ86164.1 - 0.0022 17.6 0.1 0.0035 16.9 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EAQ86164.1 - 0.0035 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAQ86164.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family CVNH PF08881.5 EAQ86165.1 - 5.8e-13 48.9 0.1 7e-13 48.7 0.1 1.3 1 1 0 1 1 1 1 CVNH domain EGF_3 PF12947.2 EAQ86165.1 - 0.15 12.0 4.6 8.8 6.3 0.6 2.7 2 0 0 2 2 2 0 EGF domain Spherulin4 PF12138.3 EAQ86166.1 - 8.4e-42 143.3 0.0 3.7e-41 141.2 0.0 1.7 2 0 0 2 2 2 1 Spherulation-specific family 4 Sod_Fe_C PF02777.13 EAQ86168.1 - 3.5e-34 116.8 0.3 6.6e-34 115.9 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EAQ86168.1 - 9.9e-34 115.4 2.2 9.9e-34 115.4 1.5 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MUG113 PF13455.1 EAQ86169.1 - 2.8e-32 111.0 0.5 7.8e-32 109.5 0.4 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EAQ86169.1 - 1.7e-23 82.9 0.2 4.8e-23 81.4 0.2 1.8 1 0 0 1 1 1 1 T5orf172 domain Ribosomal_60s PF00428.14 EAQ86171.1 - 1.5 9.2 12.3 0.28 11.5 5.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein p450 PF00067.17 EAQ86172.1 - 2.1e-13 49.6 0.0 8.6e-06 24.5 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Radical_SAM PF04055.16 EAQ86175.1 - 1.5e-15 57.8 0.0 4.4e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EAQ86175.1 - 4.7e-13 48.9 0.0 2.9e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CoA_binding PF02629.14 EAQ86176.1 - 1.7e-26 92.5 5.0 8e-26 90.3 0.6 2.4 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EAQ86176.1 - 7.1e-24 84.1 0.1 1.3e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EAQ86176.1 - 9.1e-09 35.0 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EAQ86176.1 - 0.00061 19.9 0.2 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EAQ86176.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UQ_con PF00179.21 EAQ86177.1 - 8.6e-27 93.2 0.3 4.4e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EAQ86177.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UEV PF05743.8 EAQ86177.1 - 0.14 11.8 0.3 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.24 EAQ86178.1 - 2.6e-25 89.1 0.2 1.6e-13 50.9 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ86178.1 - 0.00019 21.5 0.0 0.00054 20.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EAQ86178.1 - 0.00032 19.7 0.0 0.0006 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EAQ86178.1 - 0.00036 20.5 0.1 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ86178.1 - 0.00044 20.2 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EAQ86178.1 - 0.0021 17.9 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ86178.1 - 0.0023 17.6 0.2 0.0086 15.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EAQ86178.1 - 0.0031 18.3 0.1 0.0096 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EAQ86178.1 - 0.0048 16.1 0.6 0.015 14.5 0.4 1.8 1 1 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 EAQ86178.1 - 0.0052 16.5 0.3 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAQ86178.1 - 0.0061 16.0 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAQ86178.1 - 0.0082 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 EAQ86178.1 - 0.0086 15.1 0.1 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EAQ86178.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EAQ86178.1 - 0.015 14.0 0.1 0.039 12.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 EAQ86178.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ86178.1 - 0.034 12.9 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 EAQ86178.1 - 0.043 13.3 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EAQ86178.1 - 0.048 12.8 0.1 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAQ86178.1 - 0.05 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EAQ86178.1 - 0.066 12.6 0.5 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EAQ86178.1 - 0.074 12.6 0.2 0.31 10.6 0.1 2.0 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 EAQ86178.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EAQ86178.1 - 0.17 12.1 0.7 0.58 10.4 0.1 2.3 2 1 0 2 2 1 0 ABC transporter Dimer_Tnp_hAT PF05699.9 EAQ86179.1 - 8.6e-13 47.7 0.1 2.1e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_L13 PF00572.13 EAQ86180.1 - 2.8e-28 98.5 0.0 5.3e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 EAQ86180.1 - 0.047 13.2 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain BAG PF02179.11 EAQ86181.1 - 1.7e-18 66.4 0.1 4.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EAQ86181.1 - 2.9e-05 23.3 0.0 6.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Glutaredoxin PF00462.19 EAQ86182.1 - 6.3e-21 74.1 0.0 9.4e-21 73.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EAQ86182.1 - 1.5e-05 25.1 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ86182.1 - 0.0019 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.1 EAQ86182.1 - 0.007 16.1 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EAQ86182.1 - 0.0076 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 EAQ86182.1 - 0.028 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 EAQ86182.1 - 0.033 14.2 0.1 0.066 13.2 0.1 1.6 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EAQ86182.1 - 0.039 14.1 0.4 0.11 12.6 0.3 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 EAQ86182.1 - 0.052 13.8 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 EAQ86182.1 - 0.087 12.8 1.0 3.2 7.7 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin ArsC PF03960.10 EAQ86182.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 2 0 0 2 2 2 0 ArsC family DSBA PF01323.15 EAQ86182.1 - 0.28 10.7 1.9 0.83 9.1 0.3 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Chalcone PF02431.10 EAQ86183.1 - 5.6e-42 143.3 0.0 1.6e-28 99.4 0.0 2.1 1 1 1 2 2 2 2 Chalcone-flavanone isomerase F-box-like PF12937.2 EAQ86184.1 - 7.4e-14 51.1 1.6 2.2e-13 49.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EAQ86184.1 - 3.1e-10 39.0 19.1 1.7 8.9 0.1 11.5 13 0 0 13 13 13 3 Leucine Rich repeat F-box PF00646.28 EAQ86184.1 - 3e-05 23.5 0.0 8.9e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EAQ86184.1 - 3.1e-05 23.6 12.8 6.2 6.6 0.0 6.7 4 1 2 7 7 7 3 Leucine rich repeat LRR_1 PF00560.28 EAQ86184.1 - 3.3e-05 23.3 19.2 16 5.9 0.0 9.5 9 1 1 10 10 10 1 Leucine Rich Repeat Ste50p-SAM PF09235.5 EAQ86184.1 - 4.4 7.4 10.1 20 5.3 0.0 5.3 5 1 2 7 7 7 0 Ste50p, sterile alpha motif Glyco_hydro_35 PF01301.14 EAQ86185.1 - 2.4e-70 237.4 0.2 1.4e-69 234.9 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EAQ86185.1 - 8.3e-61 204.5 0.0 1.3e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EAQ86185.1 - 6.5e-23 79.9 0.2 1.2e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 BetaGal_dom4_5 PF13364.1 EAQ86185.1 - 2.1e-19 69.8 0.3 6.8e-19 68.1 0.2 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.10 EAQ86185.1 - 1.3e-06 27.7 0.1 0.0054 15.9 0.1 2.9 1 1 1 2 2 2 2 Beta-galactosidase Cellulase PF00150.13 EAQ86185.1 - 0.0016 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FISNA PF14484.1 EAQ86186.1 - 0.091 12.7 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 Fish-specific NACHT associated domain Sugar_tr PF00083.19 EAQ86187.1 - 2.2e-70 237.4 19.4 2.5e-70 237.3 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ86187.1 - 5.6e-15 54.9 33.0 5.6e-15 54.9 22.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily GST_C_3 PF14497.1 EAQ86188.1 - 3.4e-12 46.7 0.0 5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ86188.1 - 0.0022 17.8 0.3 0.0037 17.1 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAQ86188.1 - 0.068 13.4 0.0 0.55 10.4 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SDF PF00375.13 EAQ86189.1 - 3.6e-81 272.9 36.8 4.5e-81 272.5 25.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4552 PF15089.1 EAQ86189.1 - 1.3 7.8 2.6 1.9 7.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4552) Rax2 PF12768.2 EAQ86190.1 - 0.0087 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.5 EAQ86190.1 - 0.043 13.1 2.7 0.11 11.8 1.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 EAQ86190.1 - 0.26 10.8 5.3 0.56 9.7 3.7 1.5 1 1 0 1 1 1 0 Podoplanin SKG6 PF08693.5 EAQ86191.1 - 0.0031 16.7 1.7 0.0074 15.5 1.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EAQ86191.1 - 0.016 14.7 0.2 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Rax2 PF12768.2 EAQ86191.1 - 0.023 13.9 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Granulin PF00396.13 EAQ86191.1 - 0.72 10.0 6.5 0.56 10.3 1.4 2.5 2 0 0 2 2 2 0 Granulin Gly_transf_sug PF04488.10 EAQ86192.1 - 2.7e-05 24.5 0.0 5.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cyclase PF04199.8 EAQ86193.1 - 3.3e-16 59.4 0.3 4.5e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase Pyr_redox_3 PF13738.1 EAQ86194.1 - 3.4e-21 76.2 0.0 3.1e-20 73.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ86194.1 - 0.00012 20.4 0.0 0.00021 19.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EAQ86194.1 - 0.0011 18.9 0.1 0.041 13.8 0.1 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EAQ86194.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EAQ86194.1 - 0.096 12.5 0.6 35 4.1 0.0 3.4 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ86194.1 - 0.11 12.2 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Swi5 PF07061.6 EAQ86195.1 - 1e-26 92.4 0.0 2.3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Swi5 Ribonuclease PF00545.15 EAQ86196.1 - 6.3e-18 64.6 0.1 7.9e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_61 PF03443.9 EAQ86198.1 - 1.6e-63 214.4 0.3 1.9e-63 214.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HET PF06985.6 EAQ86199.1 - 2.6e-14 53.5 0.0 9.1e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pap_E4 PF02711.9 EAQ86201.1 - 6.6 7.6 12.9 5.4 7.9 8.2 1.4 1 1 0 1 1 1 0 E4 protein TFIIA PF03153.8 EAQ86201.1 - 7.1 6.4 7.9 7.4 6.3 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.18 EAQ86202.1 - 2.1e-15 57.3 0.0 4.2e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lantibiotic_a PF14867.1 EAQ86202.1 - 0.038 13.2 0.3 0.08 12.2 0.2 1.5 1 0 0 1 1 1 0 Lantibiotic alpha Beta-lactamase PF00144.19 EAQ86203.1 - 4e-36 124.6 0.0 9.9e-36 123.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Fasciclin PF02469.17 EAQ86204.1 - 4.4e-39 133.4 0.1 8.6e-24 83.9 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain adh_short PF00106.20 EAQ86205.1 - 7.3e-19 68.2 0.1 1.1e-18 67.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ86205.1 - 7e-11 42.1 0.1 9.6e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ86205.1 - 3.1e-06 27.1 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ86205.1 - 0.00026 20.5 0.0 0.00053 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ86205.1 - 0.00088 19.3 0.5 0.013 15.5 0.4 2.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ86205.1 - 0.005 16.1 0.3 0.0068 15.6 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family HeLo PF14479.1 EAQ86206.1 - 4.5e-18 65.7 0.0 8.8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 EAQ86206.1 - 1.5e-09 37.7 0.5 1.3e-08 34.6 0.1 2.5 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EAQ86206.1 - 5.1e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ86206.1 - 0.00037 20.5 0.0 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 EAQ86206.1 - 0.0024 17.4 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EAQ86206.1 - 0.013 15.1 0.0 0.064 12.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EAQ86206.1 - 0.024 13.4 0.0 0.052 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.12 EAQ86206.1 - 0.03 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EAQ86206.1 - 0.038 13.1 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAQ86206.1 - 0.043 14.6 0.0 0.31 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ86206.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EAQ86206.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ86206.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EAQ86206.1 - 0.096 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EAQ86206.1 - 0.096 12.1 0.2 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EAQ86206.1 - 0.17 11.7 0.3 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.18 EAQ86207.1 - 1.6e-18 66.5 3.1 3.1e-18 65.5 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ86207.1 - 4.4e-11 42.5 0.1 1e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like DDE_1 PF03184.14 EAQ86209.1 - 1.2e-30 106.2 0.0 5.2e-27 94.4 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ86209.1 - 0.0046 16.7 0.1 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF904 PF06005.7 EAQ86209.1 - 0.13 12.6 0.1 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) WES_acyltransf PF03007.11 EAQ86209.1 - 1.1 8.7 5.6 0.21 11.1 1.5 1.4 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Glyco_hydro_47 PF01532.15 EAQ86211.1 - 4.3e-153 510.2 0.0 1e-151 505.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 RVT_1 PF00078.22 EAQ86212.1 - 2.4e-12 46.6 0.0 5.4e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) TauD PF02668.11 EAQ86213.1 - 1e-26 94.1 0.1 2e-26 93.2 0.1 1.4 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.1 EAQ86213.1 - 0.052 12.5 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus DUF1996 PF09362.5 EAQ86214.1 - 1.5e-55 188.4 3.7 2e-55 188.0 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Patatin PF01734.17 EAQ86217.1 - 1.1e-21 77.7 0.1 2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_4 PF13637.1 EAQ86217.1 - 1.9e-06 28.2 0.1 5.4e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ86217.1 - 5.3e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-B_box PF00643.19 EAQ86217.1 - 0.00018 21.3 4.5 0.00018 21.3 3.1 2.4 2 0 0 2 2 2 1 B-box zinc finger Ank_5 PF13857.1 EAQ86217.1 - 0.00037 20.6 0.1 0.00096 19.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EAQ86217.1 - 0.0007 19.2 1.0 0.0025 17.5 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EAQ86217.1 - 0.011 15.9 0.1 0.092 13.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Pept_tRNA_hydro PF01195.14 EAQ86219.1 - 5.8e-24 84.5 0.0 7.3e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DDE_3 PF13358.1 EAQ86220.1 - 4.4e-05 23.2 0.0 7.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ86220.1 - 0.00057 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 EAQ86220.1 - 0.044 13.7 0.2 7.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain BAR PF03114.13 EAQ86221.1 - 6.3e-64 215.6 3.1 8.1e-64 215.2 2.1 1.1 1 0 0 1 1 1 1 BAR domain BAR PF03114.13 EAQ86222.1 - 6.5e-52 176.3 3.2 8.2e-52 175.9 2.2 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EAQ86222.1 - 2.1e-05 23.5 2.4 3.2e-05 22.9 1.7 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6 PF04111.7 EAQ86222.1 - 0.027 13.5 4.1 0.042 12.9 2.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IMD PF08397.6 EAQ86222.1 - 0.13 11.5 5.2 0.18 11.1 1.5 2.4 2 1 0 2 2 2 0 IRSp53/MIM homology domain Herpes_UL25 PF01499.11 EAQ86222.1 - 0.14 10.4 2.3 0.19 10.0 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family IncA PF04156.9 EAQ86222.1 - 1.6 8.2 6.7 2.4 7.6 4.6 1.2 1 0 0 1 1 1 0 IncA protein Cyclin_N PF00134.18 EAQ86223.1 - 5e-06 26.1 0.0 1.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain UQ_con PF00179.21 EAQ86224.1 - 2.9e-16 59.1 0.0 5.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ammonium_transp PF00909.16 EAQ86225.1 - 1e-120 402.9 27.8 1.1e-120 402.7 19.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Con-6 PF10346.4 EAQ86228.1 - 3.1e-17 61.6 0.8 3.1e-17 61.6 0.6 2.2 3 0 0 3 3 3 1 Conidiation protein 6 Toxin_52 PF15605.1 EAQ86228.1 - 0.049 13.5 1.1 0.074 12.9 0.5 1.5 1 1 0 1 1 1 0 Putative toxin 52 DLH PF01738.13 EAQ86229.1 - 4.4e-14 52.2 0.0 7.6e-14 51.5 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAQ86229.1 - 2.9e-07 30.3 0.1 3.7e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ86229.1 - 2.7e-05 24.1 4.4 0.0022 17.9 2.3 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ86229.1 - 0.002 17.3 0.1 0.047 12.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family 2-Hacid_dh_C PF02826.14 EAQ86231.1 - 8.6e-37 125.9 0.0 1.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ86231.1 - 2e-10 40.2 0.0 2.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAQ86231.1 - 3.6e-05 23.6 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EAQ86231.1 - 0.028 14.8 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyridox_oxidase PF01243.15 EAQ86231.1 - 0.044 13.8 0.3 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Podoplanin PF05808.6 EAQ86232.1 - 0.0005 19.6 1.6 0.00086 18.8 1.1 1.3 1 0 0 1 1 1 1 Podoplanin DUF1191 PF06697.7 EAQ86232.1 - 0.084 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Beta-APP PF03494.8 EAQ86232.1 - 0.31 10.5 5.1 0.6 9.6 3.5 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Formyl_trans_N PF00551.14 EAQ86233.1 - 4.1e-36 124.2 0.0 5.4e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 EAQ86233.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase F-box-like PF12937.2 EAQ86234.1 - 0.00068 19.3 0.1 0.0028 17.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAQ86234.1 - 0.0032 17.0 5.6 14 5.4 0.0 4.5 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EAQ86234.1 - 0.068 12.8 0.2 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 F-box domain TAFH PF07531.9 EAQ86234.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF DUF2457 PF10446.4 EAQ86234.1 - 1.3 7.6 10.8 1.8 7.1 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 EAQ86234.1 - 1.4 8.0 8.8 2.1 7.4 6.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 EAQ86234.1 - 2.3 7.7 7.3 4.6 6.7 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin HHH PF00633.18 EAQ86236.1 - 0.12 12.1 1.3 0.29 10.9 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix motif ThiF PF00899.16 EAQ86236.1 - 0.15 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 ThiF family LEA_2 PF03168.8 EAQ86239.1 - 0.074 13.4 0.4 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein MIP-T3 PF10243.4 EAQ86239.1 - 2.5 6.4 5.4 3.3 6.0 3.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sulfotransfer_3 PF13469.1 EAQ86240.1 - 0.017 16.0 0.3 0.047 14.6 0.2 1.9 1 1 0 1 1 1 0 Sulfotransferase family ABC_tran PF00005.22 EAQ86241.1 - 4.6e-35 120.8 0.0 5.6e-25 88.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAQ86241.1 - 5.1e-24 85.1 12.1 2.9e-19 69.5 3.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EAQ86241.1 - 1.3e-09 38.4 0.7 0.018 15.0 0.0 4.2 3 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 EAQ86241.1 - 2.2e-07 30.1 0.3 0.002 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAQ86241.1 - 2.4e-07 30.9 0.4 0.038 14.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EAQ86241.1 - 5.4e-07 29.0 1.4 0.0042 16.3 0.1 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAQ86241.1 - 6.1e-07 28.8 1.3 0.0035 16.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAQ86241.1 - 2.4e-06 28.0 0.4 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EAQ86241.1 - 2.5e-06 27.1 0.6 0.0095 15.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 EAQ86241.1 - 2.5e-06 27.2 0.8 0.056 13.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EAQ86241.1 - 8.8e-06 25.6 0.3 0.0045 16.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 EAQ86241.1 - 9.4e-06 25.5 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EAQ86241.1 - 1.2e-05 24.9 2.5 0.019 14.4 0.0 3.5 4 0 0 4 4 3 2 AAA-like domain cobW PF02492.14 EAQ86241.1 - 2e-05 24.0 2.9 0.036 13.5 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EAQ86241.1 - 3.9e-05 22.6 0.1 0.072 11.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EAQ86241.1 - 7.1e-05 22.2 0.1 0.22 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EAQ86241.1 - 7.2e-05 23.2 1.3 0.003 17.9 0.2 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EAQ86241.1 - 8.5e-05 22.4 0.1 0.034 14.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EAQ86241.1 - 0.00011 22.2 2.9 0.39 10.6 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EAQ86241.1 - 0.00029 21.6 1.5 0.79 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Septin PF00735.13 EAQ86241.1 - 0.00039 19.5 0.2 0.42 9.5 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_14 PF13173.1 EAQ86241.1 - 0.00067 19.5 0.1 0.56 10.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EAQ86241.1 - 0.001 19.3 0.5 1.1 9.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAQ86241.1 - 0.0021 17.1 0.3 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EAQ86241.1 - 0.0041 16.7 1.7 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 EAQ86241.1 - 0.0044 15.6 0.8 0.97 7.9 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EAQ86241.1 - 0.0061 16.2 3.0 0.87 9.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ATP_bind_1 PF03029.12 EAQ86241.1 - 0.0064 16.0 0.6 3 7.3 0.1 3.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EAQ86241.1 - 0.0095 15.4 0.4 1.4 8.4 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 EAQ86241.1 - 0.011 15.6 1.5 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 EAQ86241.1 - 0.015 15.5 0.1 6.8 6.9 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ86241.1 - 0.016 14.9 0.8 2.4 7.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 EAQ86241.1 - 0.018 13.7 0.2 0.11 11.0 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_19 PF13245.1 EAQ86241.1 - 0.03 14.0 1.4 3.1 7.6 0.1 3.3 3 0 0 3 3 2 0 Part of AAA domain AAA_28 PF13521.1 EAQ86241.1 - 0.032 14.1 1.1 8.4 6.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EAQ86241.1 - 0.034 13.6 0.9 2.3 7.6 0.0 2.7 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EAQ86241.1 - 0.035 13.7 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_15 PF13175.1 EAQ86241.1 - 0.037 13.0 0.0 0.63 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EAQ86241.1 - 0.045 13.9 0.9 15 5.7 0.1 2.8 2 1 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.22 EAQ86241.1 - 0.052 12.9 0.4 0.48 9.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 EAQ86241.1 - 0.13 10.7 0.1 0.37 9.3 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.1 EAQ86241.1 - 0.15 11.6 2.1 9.3 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 EAQ86241.1 - 0.16 11.2 0.8 4 6.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.4 EAQ86241.1 - 0.22 11.0 1.1 14 5.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.11 EAQ86242.1 - 0.00011 21.0 3.3 0.0015 17.3 2.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EAQ86242.1 - 0.025 12.7 0.0 0.037 12.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Methyltransf_18 PF12847.2 EAQ86243.1 - 3.1e-08 34.1 0.0 7.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ86243.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EAQ86243.1 - 2.2e-05 25.2 0.0 5.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ86243.1 - 0.00023 20.7 0.0 0.0005 19.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ86243.1 - 0.0034 17.8 0.0 0.012 16.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAQ86243.1 - 0.0035 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EAQ86243.1 - 0.012 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EAQ86243.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EAQ86243.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 EAQ86243.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EAQ86243.1 - 0.2 10.7 0.0 0.49 9.4 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase DUF3328 PF11807.3 EAQ86244.1 - 7e-35 120.6 3.9 4.1e-34 118.1 2.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Y_Y_Y PF07495.8 EAQ86245.1 - 0.15 11.8 0.8 0.22 11.2 0.5 1.2 1 0 0 1 1 1 0 Y_Y_Y domain DUF3660 PF12398.3 EAQ86246.1 - 0.021 14.7 0.0 1.5e+02 2.3 0.0 4.7 5 0 0 5 5 5 0 Receptor serine/threonine kinase nsp8 PF08717.5 EAQ86246.1 - 0.081 12.5 4.1 9.1 5.8 0.1 4.2 1 1 4 5 5 5 0 nsp8 replicase PNGaseA PF12222.3 EAQ86246.1 - 0.38 9.5 8.0 2.1 7.1 0.2 2.9 1 1 2 3 3 3 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A MOSC PF03473.12 EAQ86246.1 - 0.44 10.0 11.6 48 3.4 0.1 5.3 1 1 5 6 6 6 0 MOSC domain HisK_N PF09385.5 EAQ86246.1 - 3.9 7.0 26.8 28 4.2 0.2 6.1 2 2 4 6 6 6 0 Histidine kinase N terminal AAA_18 PF13238.1 EAQ86246.1 - 4.2 7.6 8.7 17 5.7 1.0 2.9 1 1 1 2 2 2 0 AAA domain SET PF00856.23 EAQ86247.1 - 9.6e-10 38.9 0.1 2.3e-08 34.5 0.0 2.5 2 1 0 2 2 2 1 SET domain FMN_bind_2 PF04299.7 EAQ86248.1 - 6.3e-53 178.7 0.0 7.5e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF3149 PF11346.3 EAQ86249.1 - 3.8 7.1 7.1 6.5 6.4 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3149) UvrD_C_2 PF13538.1 EAQ86250.1 - 0.0018 18.3 0.0 0.0042 17.2 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain CFEM PF05730.6 EAQ86251.1 - 1.1e-12 47.5 7.1 1.6e-12 47.0 4.9 1.2 1 0 0 1 1 1 1 CFEM domain p450 PF00067.17 EAQ86255.1 - 1.7e-91 307.0 0.0 1.9e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ParA PF10609.4 EAQ86257.1 - 1.5e-36 124.0 0.1 3e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EAQ86257.1 - 1.5e-14 53.8 0.0 2.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EAQ86257.1 - 3e-07 29.7 0.0 8.7e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EAQ86257.1 - 1.9e-06 27.1 0.7 3.1e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EAQ86257.1 - 3.3e-06 27.1 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EAQ86257.1 - 0.00025 19.9 0.4 0.00038 19.3 0.3 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EAQ86257.1 - 0.0016 17.8 0.1 0.0034 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EAQ86257.1 - 0.0024 17.2 0.3 0.0046 16.3 0.2 1.6 1 1 0 1 1 1 1 YhjQ protein AAA_26 PF13500.1 EAQ86257.1 - 0.0033 17.0 0.2 2.2 7.8 0.3 2.3 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 EAQ86257.1 - 0.016 14.8 0.1 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 EAQ86257.1 - 0.046 12.8 1.7 0.091 11.9 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EAQ86257.1 - 0.082 12.3 0.1 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.1 EAQ86257.1 - 0.098 12.6 1.1 0.17 11.8 0.4 1.6 2 0 0 2 2 2 0 AAA ATPase domain APH PF01636.18 EAQ86258.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ86258.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase SAM_decarbox PF01536.11 EAQ86259.1 - 1.8e-86 289.8 0.0 9.5e-84 280.8 0.0 3.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase Ank_2 PF12796.2 EAQ86260.1 - 9.7e-16 57.8 0.0 1.7e-05 25.0 0.0 4.7 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ86260.1 - 2.7e-11 43.6 3.2 0.0031 17.9 0.0 5.8 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86260.1 - 2e-08 33.6 0.0 0.57 10.5 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.1 EAQ86260.1 - 2.9e-07 30.5 4.7 0.12 12.6 0.0 5.6 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.25 EAQ86260.1 - 1e-05 25.0 0.9 0.031 14.0 0.0 5.7 7 1 1 8 8 8 1 Ankyrin repeat AnfO_nitrog PF09582.5 EAQ86260.1 - 0.27 10.3 0.0 0.65 9.1 0.0 1.6 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Pro_CA PF00484.14 EAQ86261.1 - 1.3e-27 96.7 0.0 1.6e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase 60KD_IMP PF02096.15 EAQ86262.1 - 7.7e-32 110.5 7.5 7.7e-32 110.5 5.2 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein TOM13 PF08219.6 EAQ86262.1 - 6e-29 99.6 0.0 2e-28 97.9 0.0 1.9 1 0 0 1 1 1 1 Outer membrane protein TOM13 MbtH PF03621.8 EAQ86262.1 - 0.096 12.0 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 MbtH-like protein SEP PF08059.8 EAQ86263.1 - 2.1e-26 91.9 0.0 4.6e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 EAQ86263.1 - 3.4e-12 45.7 0.3 5.6e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EAQ86263.1 - 1.6e-05 24.8 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Nucleoplasmin PF03066.10 EAQ86263.1 - 0.12 11.8 0.7 0.25 10.8 0.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Gtr1_RagA PF04670.7 EAQ86264.1 - 2.6e-97 324.5 0.0 3.3e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EAQ86264.1 - 3e-09 36.3 0.1 4.6e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EAQ86264.1 - 1.3e-08 34.4 0.1 2.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EAQ86264.1 - 3.4e-06 26.9 0.0 7.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ86264.1 - 3.1e-05 24.4 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EAQ86264.1 - 0.0012 18.3 0.5 0.0092 15.4 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EAQ86264.1 - 0.0096 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EAQ86264.1 - 0.0097 16.2 0.3 0.022 15.0 0.2 1.6 1 1 0 1 1 1 1 ABC transporter G-alpha PF00503.15 EAQ86264.1 - 0.012 14.3 0.3 0.22 10.1 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 EAQ86264.1 - 0.018 13.9 0.1 0.018 13.9 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EAQ86264.1 - 0.029 13.8 0.3 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EAQ86264.1 - 0.091 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Arylsulfotran_2 PF14269.1 EAQ86266.1 - 8e-73 245.1 2.2 1.1e-72 244.6 1.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EAQ86266.1 - 1.8e-18 66.3 0.5 2.9e-17 62.3 0.4 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 EAQ86267.1 - 7.1e-42 143.3 45.4 2.6e-41 141.5 31.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ86267.1 - 2e-14 53.0 30.8 4.7e-13 48.5 11.7 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EAQ86267.1 - 6.2e-08 31.3 9.8 6.2e-08 31.3 6.8 2.0 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.2 EAQ86268.1 - 8.6e-59 195.8 19.5 1.7e-16 60.3 0.0 11.5 6 4 3 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86268.1 - 1.5e-37 125.5 14.2 5.1e-05 22.8 0.0 15.9 16 1 0 16 16 16 10 Ankyrin repeat Ank_4 PF13637.1 EAQ86268.1 - 3.8e-31 106.8 8.7 7.1e-07 29.5 0.0 13.0 8 5 4 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86268.1 - 7.1e-28 93.8 16.6 0.00062 19.7 0.0 15.5 15 2 2 17 17 17 4 Ankyrin repeat Ank_5 PF13857.1 EAQ86268.1 - 1.3e-15 57.0 8.4 0.00048 20.2 0.0 10.0 9 1 2 11 11 11 4 Ankyrin repeats (many copies) Zn_clus PF00172.13 EAQ86269.1 - 2.4e-06 27.3 8.7 4.5e-06 26.4 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP PF01161.15 EAQ86270.1 - 1e-18 67.5 0.5 1.8e-18 66.8 0.4 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.9 EAQ86271.1 - 1.8e-149 497.6 0.1 2.2e-149 497.3 0.1 1.1 1 0 0 1 1 1 1 Erythromycin esterase Con-6 PF10346.4 EAQ86273.1 - 1.2e-17 63.0 0.4 2.2e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 Conidiation protein 6 SpoIIIAH PF12685.2 EAQ86273.1 - 0.028 13.9 2.4 0.03 13.8 1.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Pol_alpha_B_N PF08418.5 EAQ86273.1 - 0.9 9.0 3.6 1 8.8 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NAM-associated PF14303.1 EAQ86273.1 - 2 8.7 5.9 2.4 8.4 4.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SRP-alpha_N PF04086.8 EAQ86273.1 - 6.8 5.9 8.2 7.9 5.7 5.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.4 EAQ86275.1 - 0.0027 16.0 17.0 0.0036 15.6 11.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 FCP1_C PF09309.5 EAQ86275.1 - 0.0077 15.5 8.9 0.017 14.4 6.1 1.5 1 0 0 1 1 1 1 FCP1, C-terminal Suf PF05843.9 EAQ86275.1 - 0.01 15.5 6.6 0.017 14.8 4.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MCPVI PF02993.9 EAQ86275.1 - 0.018 15.1 6.3 0.033 14.3 4.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI FLO_LFY PF01698.11 EAQ86275.1 - 0.028 13.2 4.7 0.042 12.6 3.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 EAQ86275.1 - 0.075 11.2 37.8 0.25 9.5 25.4 1.9 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 EAQ86275.1 - 0.081 12.9 9.0 0.15 12.1 6.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ycf1 PF05758.7 EAQ86275.1 - 0.083 10.5 5.0 0.11 10.2 3.5 1.1 1 0 0 1 1 1 0 Ycf1 Ndc1_Nup PF09531.5 EAQ86275.1 - 0.1 10.9 3.2 0.14 10.5 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Serinc PF03348.10 EAQ86275.1 - 0.11 11.1 4.3 0.16 10.6 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 EAQ86275.1 - 0.16 11.8 0.7 0.26 11.1 0.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.3 EAQ86275.1 - 0.2 10.9 9.0 0.33 10.2 6.3 1.3 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.12 EAQ86275.1 - 0.23 11.2 5.6 0.39 10.4 3.9 1.3 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 EAQ86275.1 - 0.53 8.8 12.5 0.74 8.3 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.9 EAQ86275.1 - 1 8.9 5.9 1.7 8.2 4.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2514 PF10721.4 EAQ86275.1 - 1.6 8.4 17.6 3.2 7.4 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4407 PF14362.1 EAQ86275.1 - 1.9 7.3 15.9 3 6.7 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mem_trans PF03547.13 EAQ86275.1 - 1.9 6.6 3.0 3.6 5.7 2.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 EAQ86275.1 - 1.9 6.0 9.0 2.5 5.6 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM51 PF15345.1 EAQ86275.1 - 2.2 7.9 11.2 3.4 7.2 7.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4175 PF13779.1 EAQ86275.1 - 3.4 5.2 34.7 5.1 4.6 24.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RED_N PF07808.8 EAQ86275.1 - 4.3 6.4 17.3 6.5 5.8 12.0 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DivIC PF04977.10 EAQ86275.1 - 6.5 6.3 20.3 5.7 6.4 11.8 2.4 2 0 0 2 2 2 0 Septum formation initiator FimP PF09766.4 EAQ86275.1 - 8.1 5.4 23.2 12 4.8 16.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein CBM_1 PF00734.13 EAQ86277.1 - 5.9e-13 48.2 10.8 5.9e-13 48.2 7.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 EAQ86277.1 - 4.7e-12 46.3 1.1 1.3e-11 44.9 0.7 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ86277.1 - 8.7e-09 35.5 0.1 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.1 EAQ86277.1 - 0.012 15.8 0.1 0.029 14.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4397) Aldo_ket_red PF00248.16 EAQ86278.1 - 0.0031 16.3 0.0 0.0035 16.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C48 PF02902.14 EAQ86280.1 - 2.3e-06 27.4 1.6 2.3e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain OPT PF03169.10 EAQ86281.1 - 1.1e-166 555.9 44.6 1.4e-166 555.5 30.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DEAD PF00270.24 EAQ86281.1 - 1.3e-39 135.3 0.0 2.6e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ86281.1 - 3.9e-21 74.6 0.0 1.2e-19 69.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ86281.1 - 4.8e-05 23.2 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EAQ86281.1 - 0.022 14.0 0.1 0.069 12.4 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_19 PF13245.1 EAQ86281.1 - 0.043 13.5 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 EAQ86281.1 - 0.073 12.0 0.0 0.17 10.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EAQ86281.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 EAQ86282.1 - 2.3e-07 30.7 2.8 5.4e-07 29.5 2.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ86282.1 - 1.5e-05 25.0 0.2 8.4e-05 22.6 0.0 2.1 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAQ86282.1 - 1.6e-05 25.0 0.0 3.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ86282.1 - 0.0046 16.6 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EAQ86282.1 - 0.011 15.5 0.0 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 EAQ86284.1 - 2.4e-17 62.6 0.8 2.4e-17 62.6 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAQ86284.1 - 1.1e-12 47.6 0.8 2.4e-12 46.5 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peroxidase_2 PF01328.12 EAQ86285.1 - 5e-37 127.2 0.2 6.5e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Late_protein_L2 PF00513.13 EAQ86285.1 - 0.066 12.0 0.1 0.078 11.8 0.1 1.2 1 0 0 1 1 1 0 Late Protein L2 CorA PF01544.13 EAQ86287.1 - 2.4e-09 36.6 0.8 5e-09 35.5 0.4 1.5 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein zf-C4_Topoisom PF01396.14 EAQ86288.1 - 0.31 10.5 2.8 2.3 7.7 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger MFS_1 PF07690.11 EAQ86289.1 - 7.1e-28 97.3 9.8 3.6e-18 65.3 4.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily GFA PF04828.9 EAQ86290.1 - 3.7e-13 49.2 4.7 5.6e-13 48.6 3.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EAQ86290.1 - 2.3 8.2 8.4 0.077 12.9 1.3 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC APH PF01636.18 EAQ86291.1 - 5.8e-13 49.1 0.8 9e-13 48.4 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ86291.1 - 0.00059 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Jnk-SapK_ap_N PF09744.4 EAQ86293.1 - 0.11 12.5 0.2 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FAD_binding_4 PF01565.18 EAQ86294.1 - 1.5e-11 43.9 0.3 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 EAQ86294.1 - 0.035 14.0 0.1 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like RHH_1 PF01402.16 EAQ86294.1 - 0.13 12.1 0.2 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Fungal_trans PF04082.13 EAQ86295.1 - 3.4e-52 176.9 0.0 4.7e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.7 EAQ86296.1 - 3.7e-08 33.2 0.0 1.6e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ86296.1 - 1.9e-05 24.7 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ86296.1 - 0.0014 18.8 0.0 0.0071 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAQ86296.1 - 0.0025 16.7 0.0 0.0045 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 EAQ86296.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ABC_tran PF00005.22 EAQ86296.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EAQ86296.1 - 0.042 13.2 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Ank_4 PF13637.1 EAQ86296.1 - 0.054 14.0 0.0 0.24 11.9 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Arch_ATPase PF01637.13 EAQ86296.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EAQ86296.1 - 0.07 13.3 0.1 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ank_5 PF13857.1 EAQ86296.1 - 0.085 13.1 0.0 0.35 11.2 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA_17 PF13207.1 EAQ86296.1 - 0.099 13.4 0.1 0.42 11.4 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EAQ86296.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAQ86296.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA PF00004.24 EAQ86296.1 - 0.11 12.6 0.0 0.6 10.3 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAQ86296.1 - 0.18 11.6 0.0 0.49 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAQ86296.1 - 0.2 11.9 0.0 0.5 10.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 EAQ86296.1 - 0.26 10.2 1.3 1.4 7.8 0.9 2.0 1 1 0 1 1 1 0 KAP family P-loop domain SlyX PF04102.7 EAQ86297.1 - 0.0069 16.7 4.2 0.074 13.4 0.7 2.8 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ86297.1 - 0.058 12.4 1.9 0.12 11.3 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ86297.1 - 0.49 10.4 6.3 0.11 12.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) RVT_1 PF00078.22 EAQ86298.1 - 1.8e-15 56.9 0.0 4e-15 55.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EAQ86298.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 RNase H Beta_helix PF13229.1 EAQ86299.1 - 1.4e-12 47.6 8.6 2.8e-08 33.6 0.4 2.6 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.1 EAQ86299.1 - 5.4e-05 22.2 0.0 8.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B NosD PF05048.8 EAQ86299.1 - 0.00023 20.4 7.8 0.042 12.9 0.2 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.6 EAQ86299.1 - 0.02 14.0 0.4 0.065 12.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) HAUS5 PF14817.1 EAQ86301.1 - 0.094 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 AAA_16 PF13191.1 EAQ86303.1 - 6.2e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ86303.1 - 4.9e-05 23.4 0.0 0.00019 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EAQ86303.1 - 0.00024 20.8 0.0 0.00092 18.9 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 EAQ86303.1 - 0.00038 20.3 3.4 0.0016 18.3 0.0 3.2 3 1 0 3 3 3 1 Alpha/beta hydrolase family AAA PF00004.24 EAQ86303.1 - 0.0016 18.6 0.0 0.0081 16.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EAQ86303.1 - 0.0018 18.4 0.0 0.051 13.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF676 PF05057.9 EAQ86303.1 - 0.011 14.9 0.0 0.028 13.7 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA_33 PF13671.1 EAQ86303.1 - 0.025 14.4 0.3 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EAQ86303.1 - 0.038 14.7 0.0 0.16 12.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 EAQ86303.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Mg_chelatase PF01078.16 EAQ86303.1 - 0.048 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EAQ86303.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ86303.1 - 0.15 12.3 0.0 0.51 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain PAS_3 PF08447.6 EAQ86304.1 - 0.026 14.6 0.3 0.067 13.3 0.1 1.8 1 1 1 2 2 2 0 PAS fold Nup54 PF13874.1 EAQ86304.1 - 0.034 13.8 4.4 0.021 14.4 1.0 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 THDPS_N_2 PF14805.1 EAQ86304.1 - 0.11 12.3 0.3 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hemerythrin PF01814.18 EAQ86304.1 - 0.11 12.6 3.6 0.23 11.6 0.5 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF3366 PF11846.3 EAQ86304.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) FliT PF05400.8 EAQ86304.1 - 0.22 11.9 10.5 0.047 14.0 1.8 2.7 2 1 0 2 2 2 0 Flagellar protein FliT Apolipoprotein PF01442.13 EAQ86304.1 - 0.43 10.0 6.8 0.95 8.9 4.7 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4132 PF13569.1 EAQ86304.1 - 0.51 9.8 4.7 0.19 11.2 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) DUF972 PF06156.8 EAQ86304.1 - 0.96 9.8 5.0 7.3 6.9 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4635 PF15466.1 EAQ86304.1 - 4.7 6.4 11.9 0.044 13.0 2.4 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) PhoU PF01895.14 EAQ86304.1 - 6.7 7.2 6.6 3.1 8.3 0.2 2.7 1 1 2 3 3 3 0 PhoU domain Ank_2 PF12796.2 EAQ86305.1 - 7.7e-42 141.5 1.8 2.9e-13 49.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86305.1 - 7e-41 136.0 7.0 7.5e-08 31.8 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 EAQ86305.1 - 2.4e-33 113.4 4.6 2.1e-07 30.9 0.1 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ86305.1 - 6e-28 96.7 0.3 2.8e-07 30.8 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86305.1 - 4.7e-24 82.0 0.7 0.0018 18.3 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat INTS5_C PF14838.1 EAQ86305.1 - 0.048 11.9 0.1 0.23 9.7 0.0 2.0 2 1 0 2 2 2 0 Integrator complex subunit 5 C-terminus DUF2353 PF09789.4 EAQ86306.1 - 0.00086 18.6 0.2 0.0011 18.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) WEMBL PF05701.6 EAQ86306.1 - 0.0052 15.3 2.2 0.009 14.5 1.5 1.4 1 1 0 1 1 1 1 Weak chloroplast movement under blue light DUF2730 PF10805.3 EAQ86306.1 - 0.0084 15.8 1.7 0.012 15.2 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Snapin_Pallidin PF14712.1 EAQ86306.1 - 0.028 14.7 0.5 0.044 14.1 0.4 1.3 1 0 0 1 1 1 0 Snapin/Pallidin MAD PF05557.8 EAQ86306.1 - 0.051 11.6 1.5 0.064 11.3 1.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Apolipoprotein PF01442.13 EAQ86306.1 - 0.07 12.6 1.7 0.1 12.1 1.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Atg14 PF10186.4 EAQ86306.1 - 0.096 11.6 0.9 0.12 11.2 0.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TSC22 PF01166.13 EAQ86306.1 - 0.14 12.1 2.3 0.28 11.1 1.3 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIVA PF05103.8 EAQ86306.1 - 0.17 11.9 1.3 0.24 11.4 0.9 1.2 1 0 0 1 1 1 0 DivIVA protein CCDC92 PF14916.1 EAQ86306.1 - 1.8 8.2 4.5 0.46 10.1 0.5 1.9 2 1 1 3 3 3 0 Coiled-coil domain of unknown function Sporozoite_P67 PF05642.6 EAQ86307.1 - 0.63 7.8 6.2 0.7 7.6 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA_int_endo PF01974.12 EAQ86308.1 - 2.1e-20 72.3 0.0 4.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EAQ86308.1 - 1.6e-07 30.7 0.0 0.00075 19.0 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Sigma70_ner PF04546.8 EAQ86308.1 - 0.0058 16.2 4.9 0.0058 16.2 3.4 2.1 2 0 0 2 2 2 1 Sigma-70, non-essential region Daxx PF03344.10 EAQ86308.1 - 0.076 11.5 13.7 0.12 10.7 9.5 1.2 1 0 0 1 1 1 0 Daxx Family Tim54 PF11711.3 EAQ86308.1 - 0.094 11.3 6.9 0.16 10.5 4.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 EAQ86308.1 - 0.17 9.7 11.3 0.24 9.3 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 EAQ86308.1 - 0.44 8.5 1.8 0.56 8.2 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 EAQ86308.1 - 0.47 8.4 6.8 0.74 7.7 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EAQ86308.1 - 2.6 7.5 15.3 5.4 6.5 10.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EAQ86308.1 - 3.3 7.3 8.7 7.8 6.1 6.0 1.5 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 EAQ86308.1 - 9 6.6 10.5 26 5.1 7.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_21 PF13506.1 EAQ86309.1 - 4.3e-11 42.4 0.0 8.3e-05 21.9 0.0 3.8 3 1 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EAQ86309.1 - 1.7e-10 41.0 0.0 4.5e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAQ86309.1 - 0.093 12.4 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EAQ86309.1 - 0.13 12.0 9.5 0.55 9.9 6.6 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 PIF1 PF05970.9 EAQ86310.1 - 2.3e-32 112.3 0.0 4.3e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 EAQ86310.1 - 1.6e-26 93.1 2.8 3.5e-22 79.0 0.2 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAQ86310.1 - 8.7e-06 25.4 0.0 2.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ86310.1 - 1.6e-05 24.9 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ86310.1 - 0.00035 20.2 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ86310.1 - 0.00066 17.5 0.0 0.0011 16.8 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EAQ86310.1 - 0.023 14.2 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 EAQ86310.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin Nif11 PF07862.6 EAQ86310.1 - 0.14 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function KAP_NTPase PF07693.9 EAQ86310.1 - 0.68 8.8 0.0 1.1 8.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain SGS PF05002.10 EAQ86311.1 - 1e-27 95.6 1.1 2.2e-27 94.6 0.8 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EAQ86311.1 - 1.8e-13 50.8 0.0 4.3e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 CS domain TPR_11 PF13414.1 EAQ86311.1 - 3e-07 29.9 3.0 3e-07 29.9 2.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EAQ86311.1 - 3.6e-06 26.4 6.9 0.26 11.2 1.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86311.1 - 7.1e-05 23.3 12.7 0.00011 22.7 6.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ86311.1 - 0.00029 20.3 4.8 0.38 10.4 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86311.1 - 0.00079 19.7 2.9 0.0025 18.0 2.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ86311.1 - 0.0017 18.2 8.4 2.5 8.0 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ86311.1 - 0.0017 18.4 2.1 0.0039 17.3 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EAQ86311.1 - 0.016 14.9 2.0 5.1 7.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP20 PF00011.16 EAQ86311.1 - 0.076 12.8 0.1 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 Hsp20/alpha crystallin family TPR_8 PF13181.1 EAQ86311.1 - 0.14 12.0 1.9 5.1 7.1 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ86311.1 - 0.35 10.7 7.1 0.24 11.3 2.5 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3446 PF11928.3 EAQ86311.1 - 6.8 6.9 10.5 10 6.3 5.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) TPR_14 PF13428.1 EAQ86311.1 - 7.5 7.4 8.4 6.7 7.6 1.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TRAPP PF04051.11 EAQ86312.1 - 1.8e-37 128.2 0.0 2.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.6 EAQ86313.1 - 6.9e-39 131.7 0.1 8.8e-39 131.3 0.0 1.1 1 0 0 1 1 1 1 Apc13p protein Hce2 PF14856.1 EAQ86314.1 - 0.056 13.3 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor NmrA PF05368.8 EAQ86317.1 - 0.0044 16.2 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family ABC_membrane PF00664.18 EAQ86320.1 - 5.8e-39 134.1 15.9 2.7e-21 76.1 3.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ86320.1 - 1.1e-31 109.9 0.0 7.1e-19 68.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAQ86320.1 - 9.4e-08 31.5 0.1 0.00087 18.5 0.0 2.9 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ86320.1 - 4.1e-05 23.6 0.2 0.061 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EAQ86320.1 - 0.00011 22.5 0.0 0.00011 22.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 EAQ86320.1 - 0.041 12.7 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EAQ86320.1 - 0.042 14.0 0.7 0.6 10.3 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ86320.1 - 0.05 13.5 0.4 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EAQ86320.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAQ86320.1 - 0.12 11.9 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EAQ86320.1 - 0.16 12.1 2.1 5 7.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain COG5 PF10392.4 EAQ86321.1 - 3.3e-06 27.1 0.0 1.3e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Golgi transport complex subunit 5 BLOC1_2 PF10046.4 EAQ86321.1 - 1.9e-05 24.7 0.0 0.0009 19.3 0.0 2.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 EAQ86321.1 - 3.9e-05 23.4 3.1 6.6e-05 22.7 2.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 EAQ86321.1 - 0.00018 21.2 0.0 0.077 12.8 0.0 1.6 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EAQ86321.1 - 0.00019 21.2 0.1 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EAQ86321.1 - 0.00036 19.8 0.8 0.00039 19.6 0.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein HSBP1 PF06825.7 EAQ86321.1 - 0.00039 19.9 0.3 0.059 12.9 0.1 3.5 1 1 1 2 2 2 1 Heat shock factor binding protein 1 Laminin_II PF06009.7 EAQ86321.1 - 0.00047 19.9 0.2 0.0028 17.4 0.0 1.9 1 1 1 2 2 2 1 Laminin Domain II SlyX PF04102.7 EAQ86321.1 - 0.00062 20.0 0.1 0.0074 16.6 0.0 2.1 1 1 1 2 2 2 1 SlyX DUF4164 PF13747.1 EAQ86321.1 - 0.0013 18.8 0.1 0.4 10.8 0.0 3.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) FlaC_arch PF05377.6 EAQ86321.1 - 0.0018 18.1 0.0 0.0058 16.4 0.0 2.0 1 1 0 1 1 1 1 Flagella accessory protein C (FlaC) ADIP PF11559.3 EAQ86321.1 - 0.0018 18.1 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Flagellin_C PF00700.16 EAQ86321.1 - 0.0033 17.5 0.6 0.03 14.4 0.2 2.3 1 1 1 2 2 2 1 Bacterial flagellin C-terminal helical region Lzipper-MIP1 PF14389.1 EAQ86321.1 - 0.004 17.2 0.0 13 5.9 0.0 3.0 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.7 EAQ86321.1 - 0.0095 15.7 0.0 0.02 14.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) MbeD_MobD PF04899.7 EAQ86321.1 - 0.01 15.6 0.2 0.54 10.1 0.0 2.5 1 1 1 2 2 2 0 MbeD/MobD like DASH_Spc19 PF08287.6 EAQ86321.1 - 0.011 15.3 0.3 0.24 10.9 0.0 2.7 1 1 1 2 2 2 0 Spc19 PilJ PF13675.1 EAQ86321.1 - 0.012 15.9 0.0 0.099 12.9 0.0 2.1 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3450 PF11932.3 EAQ86321.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MIS13 PF08202.6 EAQ86321.1 - 0.014 14.4 0.0 0.38 9.7 0.0 2.0 1 1 1 2 2 2 0 Mis12-Mtw1 protein family PspA_IM30 PF04012.7 EAQ86321.1 - 0.015 14.6 0.0 0.16 11.2 0.0 1.5 1 1 1 2 2 2 0 PspA/IM30 family NPV_P10 PF05531.7 EAQ86321.1 - 0.017 15.3 2.1 0.37 11.0 0.6 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 EAQ86321.1 - 0.017 12.7 0.0 0.019 12.5 0.0 1.0 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.1 EAQ86321.1 - 0.026 13.0 0.0 0.028 12.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain RmuC PF02646.11 EAQ86321.1 - 0.032 13.0 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 RmuC family Fib_alpha PF08702.5 EAQ86321.1 - 0.035 14.2 0.0 0.63 10.1 0.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1192 PF06698.6 EAQ86321.1 - 0.048 13.4 0.2 8 6.3 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Nsp1_C PF05064.8 EAQ86321.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF948 PF06103.6 EAQ86321.1 - 0.069 13.0 0.3 0.8 9.6 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LPP PF04728.8 EAQ86321.1 - 0.071 12.9 0.5 5.6 6.8 0.0 3.5 2 1 2 4 4 4 0 Lipoprotein leucine-zipper Streptin-Immun PF11083.3 EAQ86321.1 - 0.076 13.0 0.0 5 7.1 0.0 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Tektin PF03148.9 EAQ86321.1 - 0.084 11.3 0.0 0.14 10.7 0.0 1.4 1 1 0 1 1 1 0 Tektin family Tropomyosin_1 PF12718.2 EAQ86321.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin like Transposase_22 PF02994.9 EAQ86321.1 - 0.11 10.9 0.0 0.19 10.1 0.0 1.5 1 1 0 1 1 1 0 L1 transposable element TMF_TATA_bd PF12325.3 EAQ86321.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF869 PF05911.6 EAQ86321.1 - 0.12 10.6 0.0 0.14 10.3 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) WXG100 PF06013.7 EAQ86321.1 - 0.13 12.2 0.1 3.8 7.5 0.0 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Tropomyosin PF00261.15 EAQ86321.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin YvrJ PF12841.2 EAQ86321.1 - 0.14 11.4 0.1 18 4.7 0.0 3.3 2 1 2 4 4 4 0 YvrJ protein family Bcr-Abl_Oligo PF09036.5 EAQ86321.1 - 0.14 12.0 0.1 1.5 8.7 0.0 2.2 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain SecY PF00344.15 EAQ86322.1 - 2.8e-96 322.4 11.6 3.5e-96 322.1 8.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EAQ86322.1 - 1.1e-18 66.4 0.4 7.2e-18 63.8 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p RseC_MucC PF04246.7 EAQ86322.1 - 4.1 6.9 5.3 0.84 9.1 0.1 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC IPPT PF01715.12 EAQ86323.1 - 2.2e-22 79.3 0.5 4.6e-22 78.2 0.4 1.6 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 EAQ86323.1 - 2.9e-06 27.2 0.3 6.4e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ86323.1 - 6.5e-05 22.9 0.4 6.5e-05 22.9 0.3 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type PSCyt3 PF07627.6 EAQ86323.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) Fungal_trans PF04082.13 EAQ86324.1 - 6.6e-16 57.9 0.0 1.4e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ86324.1 - 1.4e-06 28.0 6.3 3e-06 27.0 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox PF00046.24 EAQ86325.1 - 1.1e-19 69.7 3.8 2.2e-19 68.7 2.6 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAQ86325.1 - 0.00071 19.2 0.6 0.0018 17.9 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain E1-E2_ATPase PF00122.15 EAQ86327.1 - 2.6e-19 69.1 0.0 6.3e-19 67.9 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ86327.1 - 8.2e-19 68.8 0.0 2.6e-17 63.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAQ86327.1 - 1.7e-13 51.1 0.0 3.3e-12 46.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ86327.1 - 1e-12 47.8 0.0 3.8e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAQ86327.1 - 0.0054 16.3 0.0 0.034 13.7 0.0 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ86327.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.15 EAQ86328.1 - 1.5e-40 138.2 0.0 3.2e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain ADH_zinc_N_2 PF13602.1 EAQ86328.1 - 2e-15 57.8 0.0 5e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CRAL_TRIO_N PF03765.10 EAQ86328.1 - 4.6e-09 36.2 1.2 1e-08 35.1 0.9 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EAQ86328.1 - 0.03 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EAQ86329.1 - 1.2e-64 218.2 0.0 1.6e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EAQ86329.1 - 9e-41 139.4 0.0 1.2e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prp19_bind PF06991.6 EAQ86330.1 - 4.3e-52 177.1 22.1 4.3e-52 177.1 15.3 2.4 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Pex14_N PF04695.8 EAQ86331.1 - 0.045 13.7 0.6 0.064 13.3 0.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Voldacs PF03517.8 EAQ86332.1 - 5.2e-21 74.9 0.1 1e-20 73.9 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Fringe PF02434.11 EAQ86332.1 - 5.2e-06 25.8 0.0 1.3e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EAQ86332.1 - 0.069 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Galactosyltransferase Gly_transf_sug PF04488.10 EAQ86333.1 - 9.4e-15 54.8 0.1 1.5e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_hydro_61 PF03443.9 EAQ86334.1 - 8.8e-54 182.6 0.0 1e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_8 PF13450.1 EAQ86336.1 - 4.2e-11 42.7 0.2 9.1e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ86336.1 - 1.2e-08 34.2 0.5 2.3e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ86336.1 - 2.2e-08 33.3 0.0 5.5e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ86336.1 - 5.5e-06 26.7 0.1 1.2e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ86336.1 - 5.6e-06 25.0 0.3 8e-06 24.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EAQ86336.1 - 7.9e-06 25.2 2.2 1.3e-05 24.4 1.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ86336.1 - 1.2e-05 24.5 0.1 0.00011 21.3 0.2 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EAQ86336.1 - 0.00019 20.6 0.5 0.0003 19.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAQ86336.1 - 0.00022 21.3 0.0 0.00092 19.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ86336.1 - 0.00028 20.8 0.3 0.00057 19.8 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ86336.1 - 0.0052 15.7 0.1 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EAQ86336.1 - 0.0058 15.5 0.5 0.0085 14.9 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EAQ86336.1 - 0.06 12.2 0.1 3.4 6.5 0.2 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EAQ86336.1 - 0.062 11.9 1.0 0.12 10.9 0.7 1.4 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 EAQ86336.1 - 0.21 11.2 1.2 0.48 10.0 0.7 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_2 PF12796.2 EAQ86338.1 - 1.5e-06 28.4 0.0 0.0099 16.1 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ86338.1 - 9.6e-05 22.7 1.3 0.03 14.8 0.0 4.0 2 2 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EAQ86338.1 - 0.0004 20.0 0.0 0.67 9.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Transferase PF02458.10 EAQ86339.1 - 1.7e-24 86.0 0.3 2e-11 42.9 0.1 3.5 3 1 0 3 3 3 3 Transferase family Glyco_hydro_61 PF03443.9 EAQ86340.1 - 8.2e-79 264.4 0.1 1.4e-78 263.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ86340.1 - 5.5e-14 51.5 9.8 1.3e-13 50.3 6.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Mito_carr PF00153.22 EAQ86341.1 - 2.2e-16 59.3 1.4 7.4e-05 22.3 0.3 5.2 4 2 0 4 4 4 3 Mitochondrial carrier protein Fer2 PF00111.22 EAQ86342.1 - 2.1e-13 49.8 0.7 3.1e-13 49.2 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HAD_2 PF13419.1 EAQ86342.1 - 0.038 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Rrp15p PF07890.7 EAQ86343.1 - 3.4e-36 124.1 8.9 7.3e-36 123.0 6.2 1.5 1 0 0 1 1 1 1 Rrp15p APH PF01636.18 EAQ86346.1 - 0.00028 20.7 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ86346.1 - 0.0042 16.6 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Endonuc_Holl PF10107.4 EAQ86349.1 - 0.74 9.4 9.1 0.3 10.7 4.3 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase VWA_3 PF13768.1 EAQ86351.1 - 1.3e-28 99.6 0.0 2.2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EAQ86351.1 - 3e-17 62.4 0.0 7.4e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EAQ86351.1 - 6e-10 39.4 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EAQ86351.1 - 2.6e-08 33.2 0.0 5.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EAQ86351.1 - 3.1e-06 26.4 0.0 6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.23 EAQ86351.1 - 0.00035 20.3 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EAQ86351.1 - 0.00094 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Glycos_transf_2 PF00535.21 EAQ86351.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Choline_transpo PF04515.7 EAQ86352.1 - 4.2e-104 347.8 17.7 4.2e-104 347.8 12.3 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter Pkinase PF00069.20 EAQ86353.1 - 6.2e-11 41.9 0.0 8.5e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86353.1 - 0.0036 16.4 0.0 0.056 12.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase CobW_C PF07683.9 EAQ86353.1 - 0.21 11.2 2.2 0.16 11.7 0.2 1.8 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain tRNA-synt_1c PF00749.16 EAQ86354.1 - 9.9e-101 336.5 0.1 1.3e-100 336.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EAQ86354.1 - 4.5e-40 137.1 0.0 7.1e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 EAQ86354.1 - 0.0034 16.5 0.2 0.0075 15.4 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FCD PF07729.7 EAQ86354.1 - 0.059 13.7 1.0 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 FCD domain COG2 PF06148.6 EAQ86355.1 - 1.7e-19 70.0 0.0 2.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EAQ86355.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Hap4_Hap_bind PF10297.4 EAQ86356.1 - 1.6e-09 37.2 7.1 6.7e-09 35.2 4.9 2.2 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EAQ86356.1 - 1e-06 28.5 14.1 0.0003 20.6 5.0 2.3 1 1 1 2 2 2 2 bZIP transcription factor CASP_C PF08172.7 EAQ86356.1 - 0.0014 17.7 0.4 0.0024 16.9 0.3 1.3 1 0 0 1 1 1 1 CASP C terminal bZIP_2 PF07716.10 EAQ86356.1 - 0.02 14.7 9.5 1.8 8.4 3.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper MAD PF05557.8 EAQ86356.1 - 0.21 9.6 5.7 0.29 9.1 3.9 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Fmp27_WPPW PF10359.4 EAQ86356.1 - 0.44 8.8 2.9 0.6 8.4 2.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain B3_4 PF03483.12 EAQ86358.1 - 3.7e-21 75.3 0.1 7.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EAQ86358.1 - 1.2e-16 60.2 0.0 1.3e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain MFS_1 PF07690.11 EAQ86359.1 - 3.2e-33 114.8 42.2 5e-33 114.2 29.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ86359.1 - 6.6e-12 44.4 11.7 6.6e-12 44.4 8.1 2.1 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EAQ86360.1 - 1.5e-29 102.8 9.2 2.1e-29 102.3 6.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EAQ86362.1 - 1.1e-35 123.5 2.2 1.3e-35 123.3 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ86362.1 - 7.9e-23 81.2 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ86362.1 - 6.5e-16 58.3 0.1 2.1e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ86362.1 - 9.4e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EAQ86362.1 - 0.0026 17.3 0.3 0.0083 15.7 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.15 EAQ86362.1 - 0.0054 16.9 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.3 EAQ86362.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EAQ86362.1 - 0.042 13.4 0.0 0.096 12.2 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 EAQ86362.1 - 0.054 12.3 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Fig1 PF12351.3 EAQ86363.1 - 1.8e-09 37.7 1.6 0.0011 18.9 0.0 2.4 3 0 0 3 3 3 2 Ca2+ regulator and membrane fusion protein Fig1 zf-C2H2 PF00096.21 EAQ86364.1 - 0.04 14.2 0.2 0.04 14.2 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ribosomal_L4 PF00573.17 EAQ86364.1 - 0.17 11.2 0.5 0.3 10.4 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Imm44 PF15584.1 EAQ86365.1 - 0.0088 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Immunity protein 44 Paramyxo_PNT PF13825.1 EAQ86365.1 - 0.08 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Nop10p PF04135.7 EAQ86367.1 - 2.9e-19 68.5 0.1 3.2e-19 68.3 0.1 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EAQ86368.1 - 1.1e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EAQ86368.1 - 0.00019 21.2 1.6 0.00047 19.9 1.1 1.7 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator HET PF06985.6 EAQ86369.1 - 1.7e-34 118.9 0.0 2.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Snapin_Pallidin PF14712.1 EAQ86370.1 - 1.3 9.3 5.8 1.1 9.5 2.4 2.0 2 0 0 2 2 2 0 Snapin/Pallidin PCRF PF03462.13 EAQ86370.1 - 3.5 7.3 7.6 0.7 9.6 0.0 3.1 3 0 0 3 3 3 0 PCRF domain CDC45 PF02724.9 EAQ86370.1 - 6.7 4.6 10.3 11 3.9 7.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.13 EAQ86373.1 - 4.3e-23 81.4 32.6 5.6e-23 81.0 22.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PRT_C PF08372.5 EAQ86373.1 - 0.47 9.9 3.8 5.1 6.5 0.1 3.0 3 0 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal Bys1 PF04681.7 EAQ86374.1 - 7.5e-13 48.4 0.0 8.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Defensin_2 PF01097.13 EAQ86375.1 - 0.00095 18.8 11.2 0.00095 18.8 7.8 3.0 2 1 0 2 2 2 1 Arthropod defensin Viral_protease PF08715.5 EAQ86375.1 - 0.014 14.5 0.2 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 Papain like viral protease DAO PF01266.19 EAQ86380.1 - 6.1e-24 84.5 0.2 1.9e-23 82.9 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.14 EAQ86380.1 - 1.4e-11 44.2 0.0 2.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Pyr_redox PF00070.22 EAQ86380.1 - 0.00032 21.0 2.4 0.076 13.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ86380.1 - 0.0068 15.3 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EAQ86380.1 - 0.013 14.0 0.0 1.7 7.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 EAQ86380.1 - 0.069 13.1 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 EAQ86381.1 - 2.2e-28 99.0 35.7 2.2e-28 99.0 24.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily GATase PF00117.23 EAQ86382.1 - 6.6e-11 42.0 0.0 8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAQ86382.1 - 0.11 11.9 0.0 1.9 7.8 0.0 2.5 2 1 0 2 2 2 0 Peptidase C26 Zn_clus PF00172.13 EAQ86383.1 - 0.034 14.0 15.1 0.067 13.1 10.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytomega_UL20A PF05984.7 EAQ86383.1 - 1.5 9.0 4.0 0.47 10.6 0.4 1.9 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Transferase PF02458.10 EAQ86384.1 - 1.2e-06 27.2 0.0 3.1e-06 25.8 0.0 1.6 2 1 0 2 2 2 1 Transferase family ketoacyl-synt PF00109.21 EAQ86385.1 - 1.6e-72 244.0 1.8 3.2e-72 243.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ86385.1 - 3.6e-62 209.2 2.7 3.7e-62 209.1 0.2 2.5 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EAQ86385.1 - 7.3e-47 159.3 0.2 4.8e-46 156.7 0.1 2.6 1 0 0 1 1 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EAQ86385.1 - 2.6e-43 148.5 1.4 5.6e-39 134.3 2.1 2.4 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EAQ86385.1 - 5.6e-41 139.1 0.3 7.3e-40 135.5 0.1 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EAQ86385.1 - 7.2e-19 67.6 0.4 3.4e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ86385.1 - 1e-15 58.7 0.0 9.7e-15 55.5 0.0 2.9 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EAQ86385.1 - 3.9e-12 46.4 0.0 1.2e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ86385.1 - 5.3e-07 29.4 0.0 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EAQ86385.1 - 9.4e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EAQ86385.1 - 9.9e-05 21.9 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ86385.1 - 0.00048 20.5 0.2 0.0035 17.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EAQ86385.1 - 0.00068 19.8 0.9 0.0027 17.9 0.6 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAS PF03059.11 EAQ86385.1 - 0.079 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein LEM PF03020.10 EAQ86385.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 LEM domain PIF1 PF05970.9 EAQ86386.1 - 9.4e-19 67.5 0.0 1.6e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ86386.1 - 2.9e-06 26.9 0.2 6.5e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ86386.1 - 0.0002 21.4 0.0 0.00061 19.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ86386.1 - 0.019 15.0 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain DDE_1 PF03184.14 EAQ86387.1 - 4.6e-28 97.8 0.0 7.1e-23 80.8 0.0 2.7 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ86387.1 - 3e-15 55.7 0.0 6.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EAQ86387.1 - 9.2e-07 28.7 0.3 4.3e-06 26.5 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease Trp_halogenase PF04820.9 EAQ86388.1 - 1.1e-25 90.1 0.0 1.8e-11 43.3 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EAQ86388.1 - 7.3e-10 38.4 0.0 2.5e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ86388.1 - 1.6e-06 27.3 0.0 5.5e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ86388.1 - 5.6e-06 26.2 0.2 3.3e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ86388.1 - 5e-05 23.2 0.0 9.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ86388.1 - 7.1e-05 22.0 0.2 0.00016 20.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ86388.1 - 0.00023 19.7 0.0 0.00037 19.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EAQ86388.1 - 0.00039 19.4 0.1 0.00059 18.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAQ86388.1 - 0.00054 18.9 0.1 0.001 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EAQ86388.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ86388.1 - 0.023 13.7 0.0 0.1 11.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EAQ86388.1 - 0.027 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EAQ86388.1 - 0.063 13.3 0.1 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EAQ86388.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EAQ86388.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EAQ86388.1 - 0.15 11.4 0.1 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 EAQ86389.1 - 1.1e-16 60.5 0.1 1.8e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ86389.1 - 5.4e-09 35.8 10.6 7.6e-09 35.3 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EAQ86390.1 - 3.2e-31 108.3 41.9 7.7e-31 107.0 29.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ86390.1 - 5.8e-12 44.6 10.4 8e-12 44.1 7.1 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EAQ86390.1 - 3 7.8 6.2 0.75 9.7 0.1 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 MNHE PF01899.11 EAQ86390.1 - 7.4 6.1 10.9 0.45 10.1 1.9 2.8 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit FAD_binding_3 PF01494.14 EAQ86391.1 - 2.2e-26 92.7 0.3 5e-26 91.5 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ86391.1 - 1.5e-07 30.6 6.9 8.6e-06 24.8 2.3 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ86391.1 - 0.00035 19.5 0.1 0.00091 18.1 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EAQ86391.1 - 0.00061 20.1 1.3 0.0017 18.7 0.9 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ86391.1 - 0.0021 17.0 0.4 1.3 7.8 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAQ86391.1 - 0.0025 17.8 1.7 0.0025 17.8 1.1 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EAQ86391.1 - 0.0035 16.2 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EAQ86391.1 - 0.0095 15.8 0.9 0.017 14.9 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ86391.1 - 0.012 14.0 0.9 0.018 13.5 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EAQ86391.1 - 0.031 12.8 1.1 1.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EAQ86391.1 - 0.034 13.8 0.2 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EAQ86391.1 - 0.039 13.0 2.1 0.069 12.2 1.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ86391.1 - 0.044 12.8 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EAQ86391.1 - 0.074 13.1 1.2 0.35 10.8 0.8 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ86391.1 - 0.083 12.6 1.7 1.5 8.6 1.2 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EAQ86391.1 - 0.12 11.2 1.7 0.21 10.3 1.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EAQ86391.1 - 0.12 11.9 0.0 0.89 9.0 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EAQ86391.1 - 0.5 9.7 1.5 0.79 9.0 1.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ketoacyl-synt PF00109.21 EAQ86392.1 - 1.2e-68 231.3 1.6 2.9e-68 230.0 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAQ86392.1 - 1.8e-33 114.8 0.0 4.7e-33 113.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EAQ86392.1 - 9e-32 110.6 0.6 2.2e-30 106.1 0.1 2.2 2 0 0 2 2 2 1 Acyl transferase domain Thiolase_N PF00108.18 EAQ86392.1 - 0.00018 20.5 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EAQ86393.1 - 3.7e-11 43.1 0.1 8e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EAQ86393.1 - 4.4e-11 43.1 0.0 1.2e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ86393.1 - 4.3e-09 36.2 0.0 9.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ86393.1 - 9.4e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ86393.1 - 2.8e-06 27.8 0.0 8.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ86393.1 - 5.4e-05 23.5 0.0 0.00018 21.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ86393.1 - 0.0018 18.5 0.0 0.0058 16.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ86393.1 - 0.004 17.1 0.2 0.026 14.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_28 PF02636.12 EAQ86393.1 - 0.053 12.8 0.1 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NAD_binding_4 PF07993.7 EAQ86394.1 - 2e-11 43.3 0.0 2.7e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAQ86394.1 - 0.0044 16.4 0.0 0.0057 16.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CBM-like PF14683.1 EAQ86395.1 - 3.8e-15 55.9 0.3 8.4e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EAQ86395.1 - 3.3e-11 43.1 0.6 1.4e-10 41.1 0.4 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EAQ86395.1 - 0.085 12.9 0.3 0.085 12.9 0.2 3.2 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain FAD_binding_4 PF01565.18 EAQ86396.1 - 6.9e-24 83.8 0.9 1.4e-23 82.9 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ86396.1 - 2.5e-09 36.8 0.0 7.3e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M16_C PF05193.16 EAQ86396.1 - 0.13 11.9 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase M16 inactive domain adh_short PF00106.20 EAQ86397.1 - 0.00016 21.6 0.0 0.00043 20.2 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ86397.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Pox_E8 PF03394.8 EAQ86398.1 - 1.6 8.0 6.8 0.35 10.2 0.2 2.3 3 0 0 3 3 3 0 Poxvirus E8 protein DUF2346 PF09803.4 EAQ86399.1 - 0.07 12.9 0.2 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) DUF1688 PF07958.6 EAQ86400.1 - 4.5e-173 575.6 0.0 5.3e-173 575.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PLU-1 PF08429.6 EAQ86402.1 - 8.1e-110 366.8 12.2 6.2e-107 357.3 8.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein ARID PF01388.16 EAQ86402.1 - 1.7e-27 95.0 0.1 5.6e-27 93.4 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 EAQ86402.1 - 1.7e-26 92.6 0.0 4.5e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EAQ86402.1 - 4.1e-16 58.4 32.9 3.5e-09 36.1 4.3 3.8 4 0 0 4 4 3 2 PHD-finger JmjN PF02375.12 EAQ86402.1 - 1.5e-14 53.1 1.7 3.4e-14 52.0 1.2 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EAQ86402.1 - 1.1e-13 51.0 7.3 2.7e-13 49.7 5.0 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger Rubredoxin PF00301.15 EAQ86402.1 - 0.0068 16.2 2.0 0.0068 16.2 1.4 3.3 2 1 0 2 2 2 1 Rubredoxin Chloroplast_duf PF14476.1 EAQ86402.1 - 0.14 10.8 1.9 0.59 8.8 0.0 2.1 2 0 0 2 2 2 0 Petal formation-expressed C1_1 PF00130.17 EAQ86402.1 - 0.69 9.6 17.8 0.32 10.7 0.5 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EAQ86402.1 - 0.75 9.0 11.4 0.76 9.0 1.2 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EAQ86402.1 - 2.6 7.4 10.7 0.25 10.6 0.5 2.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EAQ86402.1 - 7.7 6.3 15.9 0.12 12.1 0.9 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Amidase_2 PF01510.20 EAQ86403.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase GIY-YIG PF01541.19 EAQ86404.1 - 4.1e-07 30.2 0.0 7.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 EAQ86404.1 - 0.00041 20.1 4.7 0.00041 20.1 3.3 1.6 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 EAQ86404.1 - 0.00044 20.1 2.9 0.00082 19.2 2.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EAQ86404.1 - 0.012 15.7 1.8 0.023 14.8 1.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EAQ86404.1 - 0.018 15.0 3.1 0.037 14.0 2.1 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.1 EAQ86404.1 - 0.041 13.5 3.9 0.11 12.1 2.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EAQ86404.1 - 0.055 13.1 5.7 0.095 12.4 4.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 EAQ86404.1 - 0.063 13.3 5.0 0.12 12.4 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EAQ86404.1 - 0.12 12.0 5.9 0.44 10.3 1.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C2HC PF01530.13 EAQ86404.1 - 0.21 11.3 3.2 0.44 10.3 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2HC type zf-RING_5 PF14634.1 EAQ86404.1 - 1 9.1 6.1 2.5 7.9 4.3 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EAQ86404.1 - 6.7 6.3 6.0 1.1e+02 2.5 4.1 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF3449 PF11931.3 EAQ86405.1 - 3.5e-67 225.7 0.6 8.9e-67 224.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EAQ86405.1 - 5.7e-12 44.9 0.0 1.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EAQ86405.1 - 1.2e-10 41.2 2.7 3.5e-08 33.3 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ86405.1 - 4.7e-09 36.1 0.9 7.4e-07 29.1 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAQ86405.1 - 0.00086 19.3 0.1 0.18 11.9 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EAQ86405.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.6 2 1 0 2 2 2 0 DBF zinc finger zf-U1 PF06220.7 EAQ86405.1 - 0.24 10.9 2.8 0.25 10.9 0.2 2.1 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_4 PF13894.1 EAQ86405.1 - 0.53 10.7 3.4 5.8 7.4 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger C1_2 PF03107.11 EAQ86405.1 - 0.98 9.5 3.5 1.7 8.8 0.5 2.5 2 0 0 2 2 2 0 C1 domain DEAD PF00270.24 EAQ86406.1 - 2.3e-41 141.0 0.4 5.9e-41 139.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ86406.1 - 4.1e-29 100.2 0.2 8.8e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EAQ86406.1 - 0.0094 15.2 0.6 0.016 14.4 0.1 1.6 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 EAQ86406.1 - 0.012 15.1 0.5 0.028 14.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ86406.1 - 0.016 14.9 0.2 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EAQ86406.1 - 0.021 14.6 0.1 0.063 13.0 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EAQ86406.1 - 0.046 13.4 0.2 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EAQ86406.1 - 0.1 12.7 1.0 0.48 10.5 0.7 2.0 1 1 0 1 1 1 0 AAA domain DUF1253 PF06862.7 EAQ86406.1 - 0.11 10.8 0.0 1 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_RecD PF05127.9 EAQ86406.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase Pro-kuma_activ PF09286.6 EAQ86408.1 - 2e-33 115.4 0.0 3.8e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EAQ86408.1 - 1.3e-06 27.8 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.11 EAQ86409.1 - 4.9e-29 101.1 47.3 2.6e-28 98.7 19.7 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ86409.1 - 2.4e-26 92.3 25.8 3.9e-21 75.1 7.5 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.14 EAQ86409.1 - 0.0092 14.5 16.2 0.0029 16.2 8.8 1.8 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF1156 PF06634.7 EAQ86409.1 - 0.047 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) PIRT PF15099.1 EAQ86409.1 - 0.19 10.9 4.0 0.092 11.9 0.4 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Peptidase_A8 PF01252.13 EAQ86409.1 - 7.1 6.2 9.3 0.58 9.7 2.5 2.1 2 1 0 2 2 2 0 Signal peptidase (SPase) II Sdh_cyt PF01127.17 EAQ86411.1 - 7.6e-19 67.7 4.2 1.1e-18 67.2 2.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 EAQ86412.1 - 7.3e-29 99.7 0.0 1.8e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EAQ86412.1 - 1.2e-19 70.0 0.0 2.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EAQ86412.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AA_permease_2 PF13520.1 EAQ86414.1 - 1.4e-51 175.4 19.4 7.2e-51 173.0 11.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EAQ86414.1 - 4.8e-16 58.1 19.0 7e-16 57.6 13.1 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EAQ86414.1 - 0.44 8.9 12.1 6.3 5.1 8.4 2.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein Glyco_hydro_61 PF03443.9 EAQ86415.1 - 1e-58 198.7 0.4 1.2e-58 198.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Melibiase PF02065.13 EAQ86416.1 - 1.9e-16 59.7 0.3 3e-13 49.2 0.0 2.7 2 1 1 3 3 3 2 Melibiase Lipase_GDSL_2 PF13472.1 EAQ86418.1 - 6.1e-19 68.8 0.0 7.9e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ86418.1 - 2.6e-17 63.4 0.0 3.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EAQ86418.1 - 8.6e-07 28.8 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family EcKinase PF02958.15 EAQ86419.1 - 4e-18 65.5 0.0 4.4e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EAQ86419.1 - 2.8e-09 37.0 1.0 5.8e-09 36.0 0.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EAQ86419.1 - 2e-05 23.4 0.0 2.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Cellulase PF00150.13 EAQ86422.1 - 4.7e-47 160.5 0.1 6.4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_61 PF03443.9 EAQ86423.1 - 6.6e-69 232.0 0.0 8.7e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EAQ86423.1 - 0.054 13.5 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PNTB PF02233.11 EAQ86424.1 - 6.1e-170 565.9 26.4 6.1e-170 565.9 18.3 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EAQ86424.1 - 1.3e-48 164.7 0.3 2.8e-48 163.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 EAQ86424.1 - 7.5e-32 109.3 3.0 7.5e-32 109.3 2.1 6.0 5 2 2 7 7 7 1 Domain of unknown function (DUF3814) AlaDh_PNT_N PF05222.10 EAQ86424.1 - 2.1e-09 37.4 0.2 5.3e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.14 EAQ86424.1 - 0.0034 16.5 0.1 2.5 7.2 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EAQ86424.1 - 0.0064 16.3 0.3 0.049 13.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 EAQ86424.1 - 0.011 15.3 0.0 0.054 13.0 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ86424.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Git3 PF11710.3 EAQ86424.1 - 0.2 11.1 0.9 0.33 10.4 0.1 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 NAD_binding_8 PF13450.1 EAQ86424.1 - 7 6.7 8.6 2 8.4 2.0 3.1 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EAQ86424.1 - 9.6 6.3 8.5 5.4 7.1 0.1 3.5 4 1 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase PLDc_2 PF13091.1 EAQ86425.1 - 5.9e-08 32.5 0.0 7.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EAQ86425.1 - 1.1e-05 24.9 1.4 0.03 14.1 0.1 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif p450 PF00067.17 EAQ86428.1 - 4.1e-48 164.0 0.0 1.4e-45 155.7 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Lipase_GDSL_2 PF13472.1 EAQ86429.1 - 2e-16 60.6 1.0 2e-16 60.6 0.7 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ86429.1 - 6.1e-13 49.1 1.5 1.4e-12 47.9 1.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pkinase PF00069.20 EAQ86430.1 - 0.026 13.6 0.0 0.29 10.2 0.0 2.5 1 1 0 1 1 1 0 Protein kinase domain Glyco_hydro_32N PF00251.15 EAQ86431.1 - 9.1e-33 113.9 2.7 5.2e-13 49.0 0.1 3.2 3 0 0 3 3 3 3 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EAQ86431.1 - 1.1e-18 67.3 0.7 3.4e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 EAQ86432.1 - 7.7e-24 84.6 7.2 8.7e-24 84.4 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain FAD_binding_3 PF01494.14 EAQ86433.1 - 5.2e-16 58.6 0.0 7e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAQ86433.1 - 1.9e-05 23.7 0.0 0.00095 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ86433.1 - 0.0023 16.8 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ86433.1 - 0.01 15.8 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAQ86433.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ86433.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MULE PF10551.4 EAQ86434.1 - 3.5e-07 30.3 0.0 2e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain IBR PF01485.16 EAQ86435.1 - 4.4e-12 45.6 47.8 9.1e-07 28.6 2.2 4.7 4 1 0 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EAQ86435.1 - 0.02 14.7 5.3 0.02 14.7 3.7 4.3 4 0 0 4 4 4 0 Ring finger domain DUF1217 PF06748.7 EAQ86435.1 - 2.7 8.0 5.8 1.1 9.3 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1217) Methyltransf_PK PF05891.7 EAQ86436.1 - 6.5e-72 241.3 0.0 7.4e-72 241.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EAQ86436.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EAQ86436.1 - 0.05 14.0 0.0 0.075 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Succ_CoA_lig PF13607.1 EAQ86436.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Ank_2 PF12796.2 EAQ86437.1 - 1.7e-22 79.5 4.7 4.7e-14 52.4 0.8 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ86437.1 - 5.3e-18 65.0 0.9 3.3e-08 33.8 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ86437.1 - 3.5e-14 51.7 5.6 1.5e-08 34.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EAQ86437.1 - 4.3e-13 49.0 3.3 2.9e-07 30.4 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86437.1 - 2.4e-12 45.8 0.8 1.2e-05 25.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ketoacyl-synt_2 PF13723.1 EAQ86437.1 - 0.0024 17.1 0.2 0.0051 16.0 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF1110 PF06533.7 EAQ86437.1 - 0.023 14.5 0.2 0.04 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1110) TPR_12 PF13424.1 EAQ86438.1 - 0.0012 18.7 8.4 0.0064 16.4 1.2 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ86438.1 - 0.0013 18.3 0.4 0.019 14.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ86438.1 - 0.019 15.4 0.3 0.14 12.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ86438.1 - 0.033 13.8 0.2 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ86438.1 - 0.054 13.1 0.5 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.1 EAQ86438.1 - 0.12 12.1 0.2 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ86438.1 - 0.23 11.4 1.2 1.8 8.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Prenyltrans PF00432.16 EAQ86439.1 - 3e-27 93.8 11.1 4.9e-10 38.7 0.2 5.2 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAQ86439.1 - 8.8e-26 90.5 4.5 8.1e-15 55.2 0.3 5.3 4 2 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAQ86439.1 - 1.3e-25 89.5 0.5 4.8e-12 45.8 0.2 6.4 3 3 3 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 EAQ86439.1 - 3.2e-07 29.8 1.0 0.31 10.1 0.0 4.9 4 1 1 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EAQ86439.1 - 4.9e-06 25.9 0.0 0.0049 16.1 0.0 3.4 3 1 1 4 4 4 2 A-macroglobulin complement component TIP120 PF08623.5 EAQ86440.1 - 1.3e-67 226.5 5.6 1.7e-64 216.4 0.2 4.6 3 1 2 5 5 5 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EAQ86440.1 - 2.9e-17 62.7 20.7 0.016 15.4 0.0 10.1 8 4 3 11 11 11 5 HEAT repeats HEAT PF02985.17 EAQ86440.1 - 3.4e-15 54.7 17.3 0.061 13.4 0.0 11.4 11 0 0 11 11 11 4 HEAT repeat Cnd1 PF12717.2 EAQ86440.1 - 1.4e-06 28.2 6.7 0.47 10.2 1.8 5.5 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EAQ86440.1 - 4e-06 27.1 20.5 0.44 11.0 0.9 11.9 11 3 3 14 14 14 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAQ86440.1 - 2.7e-05 24.4 4.5 0.17 12.2 0.0 6.1 8 2 2 10 10 10 2 Vacuolar 14 Fab1-binding region VHS PF00790.14 EAQ86440.1 - 0.0011 18.6 0.0 0.46 10.1 0.1 2.8 2 0 0 2 2 2 2 VHS domain RasGEF_N_2 PF14663.1 EAQ86440.1 - 0.15 11.9 1.2 6.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SpoIIIAH PF12685.2 EAQ86441.1 - 0.0061 16.0 7.0 0.007 15.8 4.9 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF3656 PF12392.3 EAQ86441.1 - 0.18 11.8 1.9 1.1 9.3 0.0 2.7 2 2 1 3 3 3 0 Collagenase Mit_KHE1 PF10173.4 EAQ86441.1 - 0.72 9.6 2.9 0.44 10.3 0.2 1.8 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related Herpes_capsid PF06112.6 EAQ86441.1 - 0.96 9.4 13.0 2 8.4 9.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DDHD PF02862.12 EAQ86441.1 - 8.5 6.1 9.9 13 5.5 6.8 1.2 1 0 0 1 1 1 0 DDHD domain Porphobil_deam PF01379.15 EAQ86442.1 - 2.2e-76 255.5 0.0 3e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EAQ86442.1 - 8.5e-19 67.4 1.8 1.6e-18 66.5 1.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.14 EAQ86443.1 - 2.8e-15 56.0 0.4 1.9e-11 43.6 0.1 2.1 1 1 1 2 2 2 2 Glycine cleavage H-protein Ras PF00071.17 EAQ86444.1 - 8.4e-12 44.7 0.8 1.9e-10 40.3 0.1 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAQ86444.1 - 0.00012 22.6 0.1 0.00016 22.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein BRCT PF00533.21 EAQ86445.1 - 2.3e-06 27.6 0.0 5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4048 PF13257.1 EAQ86446.1 - 2e-12 47.3 12.8 2e-12 47.3 8.8 4.0 3 2 1 4 4 4 2 Domain of unknown function (DUF4048) ATP-synt_ab PF00006.20 EAQ86447.1 - 2.7e-74 249.2 0.0 3.7e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAQ86447.1 - 7.1e-15 55.4 0.1 1.3e-14 54.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain N-SET PF11764.3 EAQ86448.1 - 5.1e-45 153.3 0.1 5.1e-45 153.3 0.1 2.8 3 1 1 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EAQ86448.1 - 4.1e-26 90.0 0.3 9.7e-26 88.8 0.2 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EAQ86448.1 - 7.7e-25 88.0 0.2 7.7e-25 88.0 0.1 3.6 3 3 0 3 3 3 1 SET domain Securin PF04856.8 EAQ86449.1 - 0.011 15.4 1.3 0.033 13.8 0.8 2.0 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor Tropomyosin_1 PF12718.2 EAQ86450.1 - 2.8e-50 169.9 34.8 3.2e-50 169.7 24.1 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EAQ86450.1 - 1.9e-09 36.9 33.9 6.3e-05 22.1 3.8 3.0 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 EAQ86450.1 - 4.6e-05 23.3 32.7 0.0069 16.2 2.2 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 EAQ86450.1 - 6.4e-05 21.2 28.0 7e-05 21.1 19.4 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Myosin_tail_1 PF01576.14 EAQ86450.1 - 0.00042 18.2 31.4 0.00048 18.0 21.7 1.0 1 0 0 1 1 1 1 Myosin tail ERM PF00769.14 EAQ86450.1 - 0.0018 17.8 35.5 0.019 14.5 9.6 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family ATG16 PF08614.6 EAQ86450.1 - 0.0022 17.8 28.1 0.022 14.5 7.7 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) IFT46_B_C PF12317.3 EAQ86450.1 - 0.0023 17.3 4.6 0.0023 17.3 3.2 1.6 1 1 1 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal Spc7 PF08317.6 EAQ86450.1 - 0.011 14.3 26.8 0.059 12.0 6.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 EAQ86450.1 - 0.019 13.9 33.9 0.13 11.2 13.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EAQ86450.1 - 0.023 14.8 19.8 2.8 8.1 7.6 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 EAQ86450.1 - 0.024 14.5 25.5 0.46 10.3 12.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EAQ86450.1 - 0.029 13.5 30.6 3.6 6.7 18.6 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 EAQ86450.1 - 0.04 13.8 33.0 0.7 9.8 8.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 EAQ86450.1 - 0.041 14.1 11.4 3.4 7.9 3.2 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 EAQ86450.1 - 0.042 13.5 27.5 0.12 12.0 12.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 EAQ86450.1 - 0.05 13.9 17.9 1 9.8 1.5 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 EAQ86450.1 - 0.06 13.1 33.4 0.36 10.5 10.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EAQ86450.1 - 0.071 13.0 27.7 1.7 8.6 1.5 4.7 1 1 3 4 4 4 0 bZIP transcription factor EzrA PF06160.7 EAQ86450.1 - 0.089 10.9 23.5 0.068 11.3 3.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.4 EAQ86450.1 - 0.11 12.4 25.6 0.25 11.3 10.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.3 EAQ86450.1 - 0.11 12.2 33.4 0.23 11.2 11.2 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EAQ86450.1 - 0.11 12.3 30.0 0.11 12.3 7.3 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LPP PF04728.8 EAQ86450.1 - 0.12 12.1 3.5 0.29 10.9 0.2 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper BRE1 PF08647.6 EAQ86450.1 - 0.14 12.0 28.3 1.3 9.0 3.8 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EAQ86450.1 - 0.23 10.6 4.6 6.4 5.8 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EAQ86450.1 - 0.28 10.9 19.7 0.029 14.1 1.9 2.2 1 1 1 2 2 2 0 Laminin Domain II Striatin PF08232.7 EAQ86450.1 - 0.36 11.1 24.1 0.19 12.0 10.5 2.2 1 1 1 2 2 2 0 Striatin family Seryl_tRNA_N PF02403.17 EAQ86450.1 - 0.45 10.5 27.4 3 7.8 0.3 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EAQ86450.1 - 0.47 10.0 30.5 11 5.5 21.1 2.1 1 1 0 1 1 1 0 IncA protein Lebercilin PF15619.1 EAQ86450.1 - 0.49 9.7 31.1 0.37 10.1 12.0 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PspA_IM30 PF04012.7 EAQ86450.1 - 0.52 9.6 30.4 1.4 8.2 5.6 2.2 1 1 1 2 2 2 0 PspA/IM30 family Atg14 PF10186.4 EAQ86450.1 - 0.59 9.0 25.8 0.43 9.4 12.0 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP_N PF15517.1 EAQ86450.1 - 0.59 9.8 2.4 2.2 7.9 0.3 2.3 2 1 0 2 2 2 0 TBP-interacting protein N-terminus KLRAQ PF10205.4 EAQ86450.1 - 0.66 10.0 21.4 0.11 12.5 6.8 2.5 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF3287 PF11690.3 EAQ86450.1 - 0.69 10.0 9.3 0.83 9.7 1.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DUF1664 PF07889.7 EAQ86450.1 - 0.74 9.6 13.9 0.96 9.2 1.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NABP PF07990.7 EAQ86450.1 - 0.88 8.7 5.8 0.96 8.6 4.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF904 PF06005.7 EAQ86450.1 - 0.93 9.8 34.9 1.1 9.5 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF904) AAA_13 PF13166.1 EAQ86450.1 - 1.1 7.6 22.4 2.6 6.4 15.6 1.6 1 1 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.4 EAQ86450.1 - 1.1 7.5 23.3 0.083 11.2 4.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4482 PF14818.1 EAQ86450.1 - 1.2 9.7 27.1 0.39 11.3 1.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) DUF972 PF06156.8 EAQ86450.1 - 1.4 9.3 25.2 30 5.0 0.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Vps5 PF09325.5 EAQ86450.1 - 1.4 8.0 23.7 0.46 9.7 9.2 2.6 1 1 2 3 3 3 0 Vps5 C terminal like Cortex-I_coil PF09304.5 EAQ86450.1 - 1.5 8.8 28.1 3.7 7.6 0.3 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF4201 PF13870.1 EAQ86450.1 - 1.7 8.0 23.7 0.67 9.3 4.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HTH_37 PF13744.1 EAQ86450.1 - 1.8 8.4 8.4 0.77 9.6 1.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain HAP1_N PF04849.8 EAQ86450.1 - 2.2 7.1 28.0 21 3.9 19.4 2.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF3450 PF11932.3 EAQ86450.1 - 2.5 7.2 26.8 5.1 6.2 8.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.10 EAQ86450.1 - 2.6 7.9 25.0 3.6 7.5 17.3 1.2 1 0 0 1 1 1 0 Fez1 DUF3584 PF12128.3 EAQ86450.1 - 2.8 5.1 27.6 4.5 4.4 19.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HalX PF08663.5 EAQ86450.1 - 3.5 7.6 20.2 16 5.5 4.2 4.3 1 1 2 3 3 3 0 HalX domain Fib_alpha PF08702.5 EAQ86450.1 - 5.1 7.2 18.4 1.3 9.1 2.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Uds1 PF15456.1 EAQ86450.1 - 5.1 7.1 24.8 26 4.8 5.4 2.4 1 1 1 2 2 2 0 Up-regulated During Septation CDC37_N PF03234.9 EAQ86450.1 - 5.7 7.2 22.4 14 5.9 15.4 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF730 PF05325.6 EAQ86450.1 - 6.6 6.5 13.7 4.5 7.1 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF730) FUSC PF04632.7 EAQ86450.1 - 7.3 4.8 7.7 8.1 4.7 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.9 EAQ86450.1 - 9 5.8 28.4 4.8 6.7 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF745 PF05335.8 EAQ86450.1 - 9.8 5.6 24.0 0.095 12.2 2.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) rRNA_proc-arch PF13234.1 EAQ86450.1 - 10 5.2 16.0 5.3e+02 -0.5 10.8 2.4 1 1 0 1 1 1 0 rRNA-processing arch domain Nop25 PF09805.4 EAQ86451.1 - 8.3e-38 129.5 10.9 8.3e-38 129.5 7.6 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.7 EAQ86452.1 - 1e-48 166.0 0.0 2.2e-48 165.0 0.0 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pro_isomerase PF00160.16 EAQ86453.1 - 2.4e-46 157.7 0.7 2.8e-46 157.5 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Syntaxin-6_N PF09177.6 EAQ86454.1 - 4.3e-25 87.9 0.1 7.9e-24 83.8 0.0 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EAQ86454.1 - 1.7e-13 50.0 8.8 2.3e-13 49.5 3.0 2.8 3 0 0 3 3 3 1 SNARE domain DUF3584 PF12128.3 EAQ86454.1 - 0.016 12.6 0.7 0.032 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Use1 PF09753.4 EAQ86454.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Spc24 PF08286.6 EAQ86454.1 - 0.027 14.1 0.9 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Myosin_tail_1 PF01576.14 EAQ86454.1 - 0.032 11.9 1.9 0.14 9.8 0.5 2.0 2 0 0 2 2 2 0 Myosin tail TBCA PF02970.11 EAQ86454.1 - 0.045 13.8 0.8 0.045 13.8 0.6 2.6 4 1 0 4 4 4 0 Tubulin binding cofactor A COG2 PF06148.6 EAQ86454.1 - 0.18 11.6 3.9 3.5 7.4 0.0 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.1 EAQ86454.1 - 0.27 11.3 4.2 0.66 10.1 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) GLE1 PF07817.8 EAQ86455.1 - 2.5e-19 69.2 0.0 4e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein PAT1 PF09770.4 EAQ86455.1 - 5 5.2 12.6 7.4 4.6 8.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNApol3-delta_C PF09115.5 EAQ86456.1 - 0.069 13.1 1.7 0.097 12.7 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Surfac_D-trimer PF09006.6 EAQ86456.1 - 0.72 9.6 5.4 1.2 8.8 3.7 1.3 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation RNB PF00773.14 EAQ86457.1 - 2.9e-75 253.5 0.0 9.4e-75 251.8 0.0 1.9 2 0 0 2 2 2 1 RNB domain GRP PF07172.6 EAQ86457.1 - 0.46 11.0 6.9 0.17 12.4 0.6 2.6 2 0 0 2 2 2 0 Glycine rich protein family SBP PF03110.9 EAQ86458.1 - 0.034 14.3 1.0 0.039 14.1 0.7 1.2 1 0 0 1 1 1 0 SBP domain Ferritin_2 PF13668.1 EAQ86459.1 - 3.7e-40 137.0 0.9 7e-40 136.1 0.6 1.4 1 0 0 1 1 1 1 Ferritin-like domain Molydop_binding PF01568.16 EAQ86459.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain ELFV_dehydrog PF00208.16 EAQ86460.1 - 5.1e-81 271.8 3.8 6.2e-81 271.5 2.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EAQ86460.1 - 3.9e-47 159.1 0.0 8.7e-47 157.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EAQ86460.1 - 0.034 14.4 0.2 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding GMC_oxred_C PF05199.8 EAQ86461.1 - 8.6e-11 42.3 0.1 2.3e-09 37.6 0.0 2.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAQ86461.1 - 0.0002 20.5 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DNA_pol_B PF00136.16 EAQ86462.1 - 4e-144 480.8 2.5 5.6e-144 480.3 1.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EAQ86462.1 - 5.2e-79 265.4 1.5 8e-79 264.8 0.4 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EAQ86462.1 - 1.2e-20 73.2 4.5 1.2e-20 73.2 3.1 1.9 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EAQ86462.1 - 9.5e-05 22.2 0.2 0.00036 20.3 0.2 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EAQ86462.1 - 0.00041 19.9 0.1 0.00087 18.8 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 EAQ86462.1 - 0.00064 18.5 3.7 0.073 11.7 0.0 3.2 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral DUF2614 PF11023.3 EAQ86462.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) C1_1 PF00130.17 EAQ86462.1 - 1.5 8.5 9.9 0.37 10.5 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF410 PF04190.8 EAQ86464.1 - 1.7e-47 162.2 0.0 2e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) UQ_con PF00179.21 EAQ86467.1 - 3e-36 123.9 0.0 3.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ86467.1 - 0.073 12.8 0.1 0.28 10.9 0.0 2.0 1 1 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.20 EAQ86468.1 - 4.4e-68 229.2 0.0 1.1e-31 109.9 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EAQ86468.1 - 6.6e-51 173.0 2.1 9.5e-50 169.2 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EAQ86468.1 - 2.7e-43 147.9 0.0 1.6e-17 63.4 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EAQ86468.1 - 1.5e-13 50.5 0.0 5.5e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 EAQ86468.1 - 1.6e-11 44.0 0.3 4.9e-11 42.5 0.2 1.9 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 EAQ86468.1 - 6.1e-06 25.3 0.0 0.00027 20.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAQ86468.1 - 4.1e-05 23.4 0.8 0.19 11.4 0.0 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family Cut12 PF11500.3 EAQ86469.1 - 1.7e-47 160.9 12.2 1.7e-47 160.9 8.4 3.9 1 1 1 3 3 3 1 Spindle pole body formation-associated protein UreF PF01730.11 EAQ86470.1 - 1.8e-13 50.8 0.2 3.1e-13 50.0 0.0 1.5 2 0 0 2 2 2 1 UreF RRM_1 PF00076.17 EAQ86471.1 - 1.2e-07 31.2 0.0 2.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ86471.1 - 6.2e-06 25.9 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ86471.1 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAQ86471.1 - 0.0026 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EAQ86471.1 - 0.033 13.8 0.7 0.071 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TGS PF02824.16 EAQ86472.1 - 1.7e-20 72.5 0.1 3e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EAQ86472.1 - 1.7e-19 69.8 0.0 4.3e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ86472.1 - 3.6e-13 49.0 0.0 5.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ86472.1 - 3.9e-05 23.5 0.3 0.034 13.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EAQ86472.1 - 0.0013 19.2 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EAQ86472.1 - 0.049 12.4 0.1 0.11 11.2 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EAQ86472.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family Spo12 PF05032.7 EAQ86473.1 - 1.1e-13 50.5 0.2 2.5e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.19 EAQ86474.1 - 7.2e-29 100.8 0.5 1.2e-28 100.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ86474.1 - 4.8e-16 58.0 0.0 1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EAQ86474.1 - 6.9e-14 52.2 1.0 1.3e-13 51.3 0.3 1.7 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAQ86474.1 - 2.3e-13 50.6 0.0 4.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain UCH_1 PF13423.1 EAQ86476.1 - 2.4e-59 201.1 0.0 4e-58 197.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NOA36 PF06524.7 EAQ86476.1 - 0.093 11.9 6.2 0.19 10.9 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein Porin_3 PF01459.17 EAQ86477.1 - 5.2e-69 232.5 0.8 7.7e-53 179.5 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic porin 6PF2K PF01591.13 EAQ86478.1 - 1.5e-50 171.3 0.7 5.6e-50 169.4 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EAQ86478.1 - 2e-21 76.7 0.2 3.2e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EAQ86478.1 - 0.032 14.1 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1501 PF07394.7 EAQ86479.1 - 0.032 13.0 0.5 0.053 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) polyprenyl_synt PF00348.12 EAQ86480.1 - 2.6e-61 206.7 0.0 3.2e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 EAQ86481.1 - 3.8e-51 172.5 0.1 2.2e-50 170.1 0.0 2.2 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EAQ86481.1 - 8.5e-20 69.4 9.4 0.00032 20.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ86481.1 - 6.2e-18 64.2 11.8 2.7e-08 33.3 0.3 6.6 4 1 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 EAQ86481.1 - 3.9e-16 57.5 8.5 0.00024 20.6 0.0 7.9 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ86481.1 - 1.7e-14 52.4 23.9 0.21 11.5 0.0 9.6 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ86481.1 - 1.4e-11 44.1 20.0 8.8e-05 22.3 0.4 7.0 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ86481.1 - 5.9e-10 38.8 16.4 0.023 15.3 0.0 8.5 6 1 3 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86481.1 - 6.1e-08 33.1 18.8 1.8e-05 25.2 0.3 7.0 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ86481.1 - 3e-06 26.9 0.5 2.4 8.5 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ86481.1 - 5.6e-06 25.7 10.6 0.095 12.5 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ86481.1 - 4.4e-05 23.2 13.5 0.012 15.4 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ86481.1 - 8.4e-05 22.6 7.4 0.58 10.3 0.1 5.0 3 1 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EAQ86481.1 - 0.0051 17.1 14.1 3.9 7.8 0.0 6.5 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ86481.1 - 0.025 14.5 8.4 5.7 7.0 0.3 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ86481.1 - 0.057 13.9 21.1 2.3 8.8 0.2 8.4 9 1 0 9 9 9 0 Tetratricopeptide repeat ChAPs PF09295.5 EAQ86481.1 - 0.06 12.1 0.0 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.2 EAQ86481.1 - 0.069 12.9 1.4 1.4 8.7 0.1 2.8 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) DUF2424 PF10340.4 EAQ86481.1 - 0.082 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MIT PF04212.13 EAQ86481.1 - 0.14 12.0 1.2 0.49 10.3 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Vps54 PF07928.7 EAQ86482.1 - 1.4e-24 86.7 0.5 3.3e-24 85.5 0.0 1.9 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EAQ86482.1 - 1e-07 31.2 1.3 2.5e-07 29.8 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EAQ86482.1 - 0.0059 16.2 0.7 0.2 11.2 0.3 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain LUC7 PF03194.10 EAQ86482.1 - 0.03 13.8 1.2 0.062 12.8 0.8 1.5 1 0 0 1 1 1 0 LUC7 N_terminus COG2 PF06148.6 EAQ86482.1 - 0.097 12.5 1.7 0.4 10.5 1.2 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.4 EAQ86482.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) DUF904 PF06005.7 EAQ86482.1 - 1.6 9.1 6.7 1.2 9.5 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) MCM PF00493.18 EAQ86483.1 - 8.4e-143 475.1 0.2 1.1e-142 474.7 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAQ86483.1 - 2.5e-17 63.4 0.5 6.1e-17 62.2 0.1 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAQ86483.1 - 3.2e-07 29.7 0.0 0.0002 20.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAQ86483.1 - 5.9e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAQ86483.1 - 0.00035 20.1 0.1 0.0017 17.9 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EAQ86483.1 - 0.013 15.8 2.3 0.025 14.9 0.7 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EAQ86483.1 - 0.05 13.0 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AMP-binding PF00501.23 EAQ86484.1 - 9.8e-17 60.4 0.1 2.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 EAQ86485.1 - 1.3e-38 132.0 0.1 2.5e-38 131.1 0.1 1.5 1 1 0 1 1 1 1 Nuclear pore complex component EHN PF06441.7 EAQ86486.1 - 7.7e-13 48.3 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hid1 PF12722.2 EAQ86487.1 - 2.8e-255 849.2 0.0 9.7e-255 847.5 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EAQ86487.1 - 5.8e-80 269.2 0.0 8.3e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MEKHLA PF08670.6 EAQ86487.1 - 0.045 13.2 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 MEKHLA domain SPC22 PF04573.7 EAQ86488.1 - 2.8e-30 104.8 0.2 4.1e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit XRN_N PF03159.13 EAQ86489.1 - 1.3e-103 345.5 0.0 2.4e-103 344.6 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus R3H PF01424.17 EAQ86489.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 R3H domain WD40 PF00400.27 EAQ86490.1 - 6e-32 108.3 1.0 2e-07 30.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAQ86490.1 - 1.4e-21 76.1 0.0 2.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SGL PF08450.7 EAQ86490.1 - 0.0042 16.4 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Parvo_coat PF00740.13 EAQ86490.1 - 0.35 9.7 7.7 0.5 9.2 5.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GAGA_bind PF06217.7 EAQ86490.1 - 2.1 8.2 17.4 3.5 7.4 12.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_23 PF13476.1 EAQ86490.1 - 3.3 7.9 17.1 5.7 7.2 11.9 1.3 1 0 0 1 1 1 0 AAA domain Zip PF02535.17 EAQ86490.1 - 6.5 5.6 5.9 12 4.7 4.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter PAS_7 PF12860.2 EAQ86491.1 - 0.095 12.7 1.8 0.21 11.5 0.5 2.1 2 0 0 2 2 2 0 PAS fold zf-RanBP PF00641.13 EAQ86492.1 - 1.7e-17 62.1 13.1 5.8e-10 38.1 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EAQ86492.1 - 9.4e-09 34.7 0.0 2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EAQ86492.1 - 8.4e-07 29.4 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EAQ86492.1 - 9.1e-06 25.5 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EAQ86492.1 - 3.2 7.6 11.1 0.52 10.1 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pmp3 PF01679.12 EAQ86493.1 - 0.00066 19.3 5.7 0.00093 18.8 4.0 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4131 PF13567.1 EAQ86493.1 - 0.003 17.0 1.5 0.0035 16.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF4401 PF14351.1 EAQ86493.1 - 0.0053 15.7 0.1 0.0059 15.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) CbiQ PF02361.11 EAQ86493.1 - 0.11 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Cobalt transport protein Pkinase PF00069.20 EAQ86495.1 - 6.7e-71 238.4 0.0 1e-70 237.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86495.1 - 8.2e-34 116.8 0.0 1.8e-33 115.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ86495.1 - 0.0082 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ86495.1 - 0.083 11.9 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FadA PF09403.5 EAQ86495.1 - 0.89 9.5 3.0 1.5 8.7 2.1 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Glycogen_syn PF05693.8 EAQ86497.1 - 0 1151.3 0.0 0 1151.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EAQ86497.1 - 2.1e-06 27.2 0.0 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EAQ86497.1 - 4.8e-06 26.2 0.1 9.7e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EAQ86497.1 - 0.00021 21.4 0.1 0.00054 20.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain F-box-like PF12937.2 EAQ86499.1 - 5.9e-05 22.7 0.3 0.00015 21.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ86499.1 - 2.5 7.8 7.3 4.2 7.1 2.4 2.9 2 1 0 2 2 2 0 F-box domain PAT1 PF09770.4 EAQ86502.1 - 0.0043 15.3 17.5 0.005 15.1 12.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 EAQ86502.1 - 0.0077 16.5 2.1 0.01 16.1 1.5 1.2 1 0 0 1 1 1 1 AAA domain Activator_LAG-3 PF11498.3 EAQ86502.1 - 0.045 12.4 23.7 0.072 11.8 16.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-DHHC PF01529.15 EAQ86502.1 - 0.13 11.6 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF4557 PF15101.1 EAQ86502.1 - 0.51 10.1 14.7 0.83 9.4 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) EphA2_TM PF14575.1 EAQ86502.1 - 0.8 10.1 8.3 2.2 8.7 5.8 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RR_TM4-6 PF06459.7 EAQ86502.1 - 1.1 9.0 10.4 0.46 10.3 4.8 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3987 PF13148.1 EAQ86502.1 - 2.5 6.6 9.6 2.4 6.6 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF4175 PF13779.1 EAQ86502.1 - 3.3 5.3 27.0 4.6 4.8 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FimP PF09766.4 EAQ86502.1 - 3.6 6.5 18.6 5.4 5.9 12.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 EAQ86502.1 - 9.4 4.8 7.7 13 4.3 5.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EIIBC-GUT_N PF03612.9 EAQ86502.1 - 9.6 5.7 9.6 34 3.9 7.0 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Glyco_hydro_61 PF03443.9 EAQ86503.1 - 2.1e-59 200.9 0.8 2.8e-59 200.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ86503.1 - 1.8e-11 43.4 12.3 5e-11 42.0 8.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain ELO PF01151.13 EAQ86504.1 - 1e-61 208.4 19.9 1.2e-61 208.1 13.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family p53-inducible11 PF14936.1 EAQ86504.1 - 0.15 11.9 1.8 3.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Tumour protein p53-inducible protein 11 COX5A PF02284.11 EAQ86505.1 - 3.1e-42 142.8 0.2 4.3e-42 142.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HDA2-3 PF11496.3 EAQ86506.1 - 4.9e-09 35.4 0.3 2.2e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EAQ86506.1 - 2e-05 24.1 0.8 4.8e-05 22.9 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IncA PF04156.9 EAQ86506.1 - 0.0054 16.3 9.9 0.0054 16.3 6.8 3.6 2 1 1 3 3 3 1 IncA protein Tropomyosin_1 PF12718.2 EAQ86506.1 - 0.14 11.9 49.6 0.022 14.6 19.4 4.1 2 1 2 4 4 4 0 Tropomyosin like Filament PF00038.16 EAQ86506.1 - 0.43 9.9 39.4 7.9 5.8 13.6 3.5 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.5 EAQ86506.1 - 2.1 8.4 25.6 0.077 13.1 7.2 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 EAQ86506.1 - 6.6 5.0 31.9 13 4.0 21.7 1.7 1 1 0 1 1 1 0 AAA domain Glyco_transf_8 PF01501.15 EAQ86507.1 - 5.9e-37 127.3 0.0 1.1e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EAQ86507.1 - 0.0043 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Cation_efflux PF01545.16 EAQ86508.1 - 5e-31 107.8 3.5 6.1e-31 107.5 2.4 1.1 1 0 0 1 1 1 1 Cation efflux family APH PF01636.18 EAQ86509.1 - 3.4e-06 26.9 0.1 8.6e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Erythro-docking PF09277.6 EAQ86509.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Erythronolide synthase, docking Hydrolase_4 PF12146.3 EAQ86510.1 - 4.3e-18 64.9 0.2 1.8e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EAQ86510.1 - 5.1e-07 29.8 3.1 1.3e-05 25.1 0.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ86510.1 - 2.2e-05 24.2 0.1 0.0013 18.5 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family GBS_Bsp-like PF08481.5 EAQ86510.1 - 0.13 12.1 2.3 0.21 11.4 1.6 1.2 1 0 0 1 1 1 0 GBS Bsp-like repeat TB2_DP1_HVA22 PF03134.14 EAQ86512.1 - 1.4e-29 101.6 6.5 1.8e-29 101.2 4.5 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Tmemb_185A PF10269.4 EAQ86512.1 - 0.036 13.6 4.8 0.049 13.2 3.3 1.2 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein DUF4407 PF14362.1 EAQ86512.1 - 0.077 11.9 1.2 0.55 9.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2583 PF10762.4 EAQ86512.1 - 0.3 11.2 2.9 0.53 10.4 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2583) Bestrophin PF01062.16 EAQ86512.1 - 7.6 5.3 8.8 36 3.1 6.1 1.8 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Mid1 PF12929.2 EAQ86513.1 - 1.7e-139 465.2 0.3 2e-139 465.0 0.2 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EAQ86513.1 - 0.1 12.9 2.0 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Fz domain Adeno_E3_14_5 PF04834.7 EAQ86514.1 - 0.0031 17.8 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 Early E3 14.5 kDa protein RAMP4 PF06624.7 EAQ86515.1 - 2.6e-05 23.6 1.1 3.5e-05 23.2 0.8 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.1 EAQ86516.1 - 9.3e-17 61.0 4.5 9.3e-17 61.0 3.1 5.2 4 1 0 4 4 4 1 Small acidic protein family DUF1777 PF08648.7 EAQ86517.1 - 1.9e-23 83.1 15.0 1.9e-23 83.1 10.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) ASXH PF13919.1 EAQ86518.1 - 9.3e-20 70.8 0.5 1.4e-19 70.2 0.4 1.2 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 EAQ86519.1 - 1.2e-25 88.8 0.1 2.1e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EAQ86519.1 - 2.2e-14 52.7 0.0 4.1e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EAQ86519.1 - 0.018 14.8 0.7 0.018 14.8 0.5 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF334 PF03904.8 EAQ86519.1 - 0.087 12.1 1.1 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF4404 PF14357.1 EAQ86519.1 - 0.16 12.4 1.0 21 5.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PilJ PF13675.1 EAQ86519.1 - 0.26 11.6 1.4 2.4 8.5 0.2 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PyrI_C PF02748.10 EAQ86520.1 - 0.0048 16.3 0.5 0.5 9.8 0.0 2.3 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2493 PF10686.4 EAQ86520.1 - 0.047 13.2 0.0 0.19 11.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) CLPTM1 PF05602.7 EAQ86521.1 - 3.6e-160 533.4 0.0 4.5e-160 533.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.9 EAQ86522.1 - 3.8e-29 101.1 0.1 6.9e-29 100.3 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EAQ86523.1 - 4e-51 173.0 0.0 5.2e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAQ86523.1 - 2.8e-11 42.5 0.2 4.8e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ATP-grasp_4 PF13535.1 EAQ86523.1 - 0.005 16.5 0.0 0.012 15.4 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Vps55 PF04133.9 EAQ86524.1 - 5e-46 155.3 7.8 5.5e-46 155.2 5.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Chorismate_bind PF00425.13 EAQ86525.1 - 5.9e-62 209.3 0.2 3.8e-34 118.1 0.0 3.1 2 1 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 EAQ86525.1 - 8e-14 51.8 0.0 1.8e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region GATase PF00117.23 EAQ86525.1 - 6.9e-07 28.8 0.0 7.2e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase class-I TRAPPC9-Trs120 PF08626.6 EAQ86526.1 - 3.3e-118 395.7 0.0 9.5e-62 208.7 0.0 2.9 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short_C2 PF13561.1 EAQ86527.1 - 7.3e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ86527.1 - 7.6e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF904 PF06005.7 EAQ86527.1 - 0.09 13.0 1.3 0.16 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2264 PF10022.4 EAQ86528.1 - 1.5e-98 329.7 4.5 1.9e-85 286.6 3.5 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 EAQ86528.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Surface antigen variable number repeat FH2 PF02181.18 EAQ86529.1 - 5.9e-71 239.3 6.4 5.9e-71 239.3 4.5 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EAQ86529.1 - 1.3e-66 223.5 0.1 4.2e-66 221.8 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EAQ86529.1 - 1.6e-52 177.7 5.8 1.6e-52 177.7 4.0 2.9 2 1 1 3 3 3 1 Diaphanous FH3 Domain PPP5 PF08321.7 EAQ86531.1 - 2.7e-31 107.4 0.1 7.1e-31 106.0 0.1 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EAQ86531.1 - 3.3e-25 87.5 1.6 9.6e-18 63.6 0.2 2.3 1 1 1 2 2 2 2 TPR repeat Metallophos PF00149.23 EAQ86531.1 - 1.1e-23 83.7 0.0 2e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_1 PF00515.23 EAQ86531.1 - 2e-18 65.1 0.1 6.9e-06 25.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ86531.1 - 1e-14 53.1 0.1 0.00024 20.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86531.1 - 1.3e-07 32.0 0.0 0.00078 20.0 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ86531.1 - 1.4e-07 31.1 1.1 0.011 15.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ86531.1 - 3.8e-06 26.6 0.0 0.0065 16.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ86531.1 - 6.8e-06 26.2 0.0 0.076 13.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86531.1 - 2.6e-05 24.4 0.0 0.085 13.2 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EAQ86531.1 - 8.8e-05 21.6 0.1 0.0095 15.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ86531.1 - 0.0031 17.3 0.3 3.3 7.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ86531.1 - 0.017 14.8 0.0 0.29 10.9 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ86531.1 - 0.018 15.4 0.8 0.37 11.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Secretin_N_2 PF07655.8 EAQ86532.1 - 0.036 14.4 4.9 0.047 14.0 1.2 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain Toxin_47 PF15527.1 EAQ86532.1 - 0.06 13.1 1.8 0.084 12.6 1.3 1.3 1 0 0 1 1 1 0 Putative toxin 47 Pkinase PF00069.20 EAQ86534.1 - 1e-45 155.9 0.0 9.5e-34 116.7 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86534.1 - 2.6e-19 69.3 0.1 3.8e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ86534.1 - 0.052 12.5 0.0 0.096 11.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 EAQ86534.1 - 0.24 10.2 0.1 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 P5-ATPase PF12409.3 EAQ86535.1 - 4.2e-40 136.3 0.0 1.3e-39 134.7 0.0 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EAQ86535.1 - 7.5e-29 101.2 0.0 1.4e-28 100.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ86535.1 - 1.6e-17 64.6 0.0 1.7e-16 61.3 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAQ86535.1 - 1.3e-11 43.9 0.3 3.5e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EAQ86535.1 - 0.00084 18.7 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 EAQ86535.1 - 0.00093 18.7 3.7 0.00093 18.7 2.5 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EAQ86535.1 - 0.014 14.9 1.1 0.81 9.2 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ86535.1 - 0.031 14.2 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit NAP PF00956.13 EAQ86536.1 - 1.3e-87 293.0 8.6 1.3e-87 293.0 6.0 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) 2-Hacid_dh_C PF02826.14 EAQ86537.1 - 9.7e-52 174.6 0.0 1.6e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ86537.1 - 6.8e-37 125.9 0.1 9.4e-37 125.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAQ86537.1 - 4.2e-06 26.6 0.1 1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EAQ86537.1 - 0.00064 19.6 0.1 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EAQ86537.1 - 0.0018 17.6 0.1 0.053 12.8 0.0 2.5 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 EAQ86537.1 - 0.004 16.5 0.0 0.016 14.6 0.0 2.1 1 0 0 1 1 1 1 ACT domain 3HCDH_N PF02737.13 EAQ86537.1 - 0.15 11.6 1.9 1.4 8.5 0.3 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myosin_head PF00063.16 EAQ86538.1 - 2e-183 611.2 7.8 5.4e-117 391.6 0.1 3.3 2 1 1 3 3 2 2 Myosin head (motor domain) DIL PF01843.14 EAQ86538.1 - 2.1e-34 117.5 4.0 6.1e-34 116.0 2.8 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EAQ86538.1 - 3.3e-12 44.8 39.2 7.8e-06 25.0 1.2 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 EAQ86538.1 - 0.00032 19.9 2.3 0.00076 18.7 1.5 1.6 1 1 0 1 1 1 1 Reovirus sigma C capsid protein GAS PF13851.1 EAQ86538.1 - 0.00045 19.4 26.4 0.0091 15.2 18.4 2.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 EAQ86538.1 - 0.0049 16.4 18.1 0.0049 16.4 12.6 2.5 2 0 0 2 2 2 1 Ezrin/radixin/moesin family AAA_22 PF13401.1 EAQ86538.1 - 0.0049 17.0 0.0 0.025 14.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EAQ86538.1 - 0.0062 16.0 0.9 0.035 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EAQ86538.1 - 0.0084 15.8 1.6 0.073 12.8 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain FlaC_arch PF05377.6 EAQ86538.1 - 0.017 15.0 0.3 0.017 15.0 0.2 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AAA_16 PF13191.1 EAQ86538.1 - 0.017 15.0 1.7 0.17 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain APG6 PF04111.7 EAQ86538.1 - 2.5 7.0 27.7 0.22 10.5 14.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 EAQ86538.1 - 3.5 7.4 12.1 12 5.6 6.5 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EAQ86538.1 - 6.8 5.5 20.2 15 4.4 14.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_18 PF13238.1 EAQ86539.1 - 8.4e-30 103.7 2.1 3.8e-29 101.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EAQ86539.1 - 2.5e-15 57.3 1.4 5.3e-15 56.3 1.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ86539.1 - 2e-05 24.4 0.1 0.0015 18.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EAQ86539.1 - 2.6e-05 24.1 0.6 0.00016 21.5 0.4 1.9 1 1 0 1 1 1 1 Shikimate kinase Cytidylate_kin2 PF13189.1 EAQ86539.1 - 5.3e-05 23.2 0.1 0.01 15.7 0.1 2.2 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.1 EAQ86539.1 - 0.00015 21.7 1.1 0.00028 20.9 0.2 1.9 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EAQ86539.1 - 0.00028 21.0 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 EAQ86539.1 - 0.0026 17.6 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase Thymidylate_kin PF02223.12 EAQ86539.1 - 0.0058 16.0 0.3 2.1 7.6 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.1 EAQ86539.1 - 0.0097 15.9 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 EAQ86539.1 - 0.0097 15.1 0.1 0.036 13.2 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 EAQ86539.1 - 0.013 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) dNK PF01712.14 EAQ86539.1 - 0.019 14.8 0.4 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_19 PF13245.1 EAQ86539.1 - 0.032 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EAQ86539.1 - 0.048 13.8 0.2 0.085 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAQ86539.1 - 0.085 11.9 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Ham1p_like PF01725.11 EAQ86540.1 - 2.1e-51 173.9 0.0 2.4e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.8 EAQ86541.1 - 4e-51 173.2 0.0 1.2e-50 171.6 0.0 1.8 1 1 1 2 2 2 1 Peptidase family C78 Peptidase_C47 PF05543.8 EAQ86541.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 tRNA-synt_2b PF00587.20 EAQ86542.1 - 6.7e-31 107.1 0.0 9.9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EAQ86542.1 - 2.5e-10 40.3 0.4 5.4e-10 39.2 0.3 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ras PF00071.17 EAQ86543.1 - 3.8e-47 159.6 0.1 4.4e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ86543.1 - 2e-15 57.3 0.1 2.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ86543.1 - 5.5e-08 32.2 0.0 6.3e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAQ86543.1 - 3.4e-06 26.9 0.0 4.6e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAQ86543.1 - 7.1e-06 25.5 0.1 5.5e-05 22.6 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EAQ86543.1 - 0.0023 17.1 0.0 0.0036 16.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EAQ86543.1 - 0.068 13.0 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain WAPL PF07814.8 EAQ86544.1 - 1.3e-17 63.5 0.4 2.4e-17 62.7 0.3 1.4 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 EAQ86545.1 - 4e-80 267.9 0.0 5.7e-80 267.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EAQ86545.1 - 0.00023 20.8 0.0 0.00061 19.5 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EAQ86545.1 - 0.096 12.4 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EAQ86546.1 - 3.5e-22 77.8 1.6 5.4e-22 77.2 1.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 EAQ86546.1 - 0.048 13.5 1.1 0.048 13.5 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EAQ86546.1 - 0.29 10.7 3.5 3.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.2 EAQ86546.1 - 0.33 10.8 4.1 0.21 11.4 1.6 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain GTP_CH_N PF12471.3 EAQ86547.1 - 6.1e-85 283.7 0.0 8.9e-85 283.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal Secretin_N PF03958.12 EAQ86548.1 - 0.018 15.2 0.2 0.032 14.3 0.2 1.4 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Ribosomal_S3Ae PF01015.13 EAQ86550.1 - 3.4e-81 271.2 3.6 4.1e-81 270.9 2.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 EAQ86550.1 - 0.01 15.9 1.0 0.063 13.4 0.0 2.5 2 1 1 3 3 3 0 Syntaxin mRNA_cap_C PF03919.10 EAQ86550.1 - 0.053 13.8 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Abhydrolase_6 PF12697.2 EAQ86551.1 - 3.2e-30 105.7 0.7 5.2e-30 105.0 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ86551.1 - 4.2e-19 69.0 0.3 2.4e-17 63.2 0.3 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ86551.1 - 6.1e-10 39.0 0.0 1.6e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EAQ86551.1 - 4.8e-06 26.9 0.0 6.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EAQ86551.1 - 8.7e-05 22.2 0.3 0.0059 16.2 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EAQ86551.1 - 0.00083 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 EAQ86551.1 - 0.032 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.6 EAQ86551.1 - 0.13 10.9 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase SRP72 PF08492.7 EAQ86552.1 - 9.7e-16 57.8 11.2 9.7e-16 57.8 7.8 1.8 2 0 0 2 2 1 1 SRP72 RNA-binding domain Apc3 PF12895.2 EAQ86552.1 - 1.2e-05 25.3 4.4 0.0039 17.2 0.6 4.7 2 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAQ86552.1 - 2.5e-05 24.1 17.5 0.14 12.1 0.1 6.1 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86552.1 - 2.7e-05 24.4 19.3 0.5 10.7 0.3 7.2 4 3 2 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ86552.1 - 6.8e-05 23.1 33.5 0.52 11.0 0.0 10.0 8 2 3 11 11 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ86552.1 - 0.0039 17.0 17.8 2.4 8.2 0.4 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86552.1 - 0.01 16.5 37.7 0.012 16.2 4.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat Sperm_Ag_HE2 PF05324.8 EAQ86552.1 - 0.017 15.0 0.2 0.044 13.7 0.1 1.7 1 0 0 1 1 1 0 Sperm antigen HE2 TPR_5 PF12688.2 EAQ86552.1 - 0.029 14.4 0.2 0.029 14.4 0.2 3.6 3 1 1 4 4 4 0 Tetratrico peptide repeat TPR_9 PF13371.1 EAQ86552.1 - 0.03 14.1 0.1 0.03 14.1 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ86552.1 - 0.091 12.4 13.8 1.8 8.2 0.1 5.4 5 2 0 5 5 5 0 TPR repeat SPO22 PF08631.5 EAQ86552.1 - 0.13 11.2 0.0 0.69 8.9 0.0 2.1 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_10 PF13374.1 EAQ86552.1 - 1 9.3 17.5 14 5.7 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ86552.1 - 2.3 8.8 11.6 27 5.5 0.3 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ86552.1 - 5.2 7.7 26.4 0.8 10.3 0.1 7.5 8 1 1 9 9 7 0 Tetratricopeptide repeat Sec7 PF01369.15 EAQ86553.1 - 1.3e-39 135.8 0.0 2.3e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EAQ86553.1 - 8.5e-06 25.9 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EAQ86553.1 - 9.5e-05 22.5 0.1 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.19 EAQ86554.1 - 3.6e-70 236.7 0.0 4.5e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase MFS_1 PF07690.11 EAQ86556.1 - 3.2e-18 65.5 47.6 2e-17 62.9 18.1 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily MS_channel PF00924.13 EAQ86556.1 - 0.41 9.9 2.7 1.1 8.5 1.9 1.7 1 0 0 1 1 1 0 Mechanosensitive ion channel FAD_binding_4 PF01565.18 EAQ86557.1 - 4.2e-16 58.6 1.9 7.5e-16 57.8 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain DUF2937 PF11157.3 EAQ86557.1 - 0.22 10.8 0.5 13 5.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Amidoligase_2 PF12224.3 EAQ86558.1 - 9.9e-18 64.6 0.0 1.4e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme HTH_Tnp_Tc3_2 PF01498.13 EAQ86559.1 - 1.9e-20 72.6 1.9 1.9e-20 72.6 1.3 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EAQ86559.1 - 1.6e-17 63.6 0.4 3e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EAQ86559.1 - 7.3e-10 38.9 2.0 1.5e-09 37.9 1.4 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EAQ86559.1 - 0.00046 19.7 0.2 0.00046 19.7 0.1 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.1 EAQ86559.1 - 0.0006 19.7 3.8 0.0023 17.9 0.0 2.9 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_32 PF13565.1 EAQ86559.1 - 0.0031 18.2 1.5 0.0031 18.2 1.0 2.1 2 1 0 2 2 1 1 Homeodomain-like domain HTH_7 PF02796.10 EAQ86559.1 - 0.014 15.2 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.8 EAQ86559.1 - 0.035 13.5 0.2 1.6 8.2 0.0 3.2 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain rve PF00665.21 EAQ86559.1 - 0.045 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HTH_38 PF13936.1 EAQ86559.1 - 0.11 12.0 1.6 0.91 9.1 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EAQ86559.1 - 0.21 10.8 5.2 7.3 5.8 0.1 4.0 3 1 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EAQ86559.1 - 0.73 9.8 4.9 0.9 9.6 0.7 2.5 2 0 0 2 2 2 0 HTH-like domain FlaG PF03646.10 EAQ86560.1 - 0.36 11.0 1.7 0.74 9.9 0.2 2.2 1 1 1 2 2 2 0 FlaG protein FCP1_C PF09309.5 EAQ86560.1 - 1 8.6 9.7 2 7.6 6.7 1.5 1 0 0 1 1 1 0 FCP1, C-terminal Pyr_redox PF00070.22 EAQ86561.1 - 5.8e-13 49.0 0.1 2.6e-10 40.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ86561.1 - 3.2e-09 36.9 0.0 5.1e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ86561.1 - 2.5e-07 30.9 1.1 0.00046 20.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ86561.1 - 0.00085 18.3 0.0 0.0085 15.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 EAQ86561.1 - 0.011 15.6 0.0 0.99 9.4 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain EutA PF06277.6 EAQ86563.1 - 0.19 10.3 1.0 0.25 9.8 0.7 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA Rep_fac-A_3 PF08661.6 EAQ86564.1 - 4.5e-22 78.0 0.0 4.9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 bZIP_1 PF00170.16 EAQ86565.1 - 5.2e-08 32.7 8.4 7e-08 32.3 5.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ86565.1 - 5.2e-07 29.3 9.2 8.8e-07 28.6 6.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper CENP-F_leu_zip PF10473.4 EAQ86565.1 - 0.01 15.6 3.4 0.015 15.1 2.4 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1690 PF07956.6 EAQ86565.1 - 0.042 13.8 1.2 0.055 13.4 0.8 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Lectin_N PF03954.9 EAQ86565.1 - 0.058 12.7 0.5 0.089 12.1 0.3 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain bZIP_Maf PF03131.12 EAQ86565.1 - 0.085 13.1 5.9 0.14 12.4 4.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EAQ86565.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EAQ86565.1 - 0.14 11.0 3.1 0.17 10.8 2.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 EAQ86565.1 - 0.25 11.3 4.2 0.37 10.7 2.9 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DivIC PF04977.10 EAQ86565.1 - 0.27 10.7 3.3 0.42 10.1 2.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Alb1 PF09135.6 EAQ86566.1 - 3.1e-26 92.1 7.9 3.1e-26 92.1 5.5 1.4 2 0 0 2 2 2 1 Alb1 UCH PF00443.24 EAQ86567.1 - 5.6e-37 127.3 0.0 7.7e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ86567.1 - 1.2e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPT PF03151.11 EAQ86568.1 - 6.3e-21 74.6 11.0 6.3e-21 74.6 7.7 3.3 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EAQ86568.1 - 0.00014 21.9 30.7 0.00066 19.7 5.4 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EAQ86568.1 - 0.00015 20.7 15.2 0.017 14.0 3.0 2.5 2 1 0 2 2 2 2 UAA transporter family COMPASS-Shg1 PF05205.7 EAQ86569.1 - 9.9e-26 90.1 0.1 2.1e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF-2B PF01008.12 EAQ86571.1 - 5.9e-45 153.4 0.0 1.5e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Stig1 PF04885.8 EAQ86571.1 - 0.0005 20.2 22.5 0.0005 20.2 15.6 2.6 1 1 2 3 3 3 1 Stigma-specific protein, Stig1 IF3_C PF00707.17 EAQ86572.1 - 1.8e-08 33.9 0.2 2.8e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EAQ86572.1 - 0.089 12.1 0.1 0.2 11.0 0.0 1.6 1 1 1 2 2 2 0 Mitochondrial translation initiation factor Peptidase_S24 PF00717.18 EAQ86573.1 - 9.5e-08 31.5 0.1 2.8e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like Arm PF00514.18 EAQ86574.1 - 3.3e-69 226.5 30.4 3.4e-13 48.8 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAQ86574.1 - 9.8e-22 77.0 15.4 2.2e-06 27.8 0.1 7.7 3 3 1 5 5 5 5 HEAT repeats HEAT PF02985.17 EAQ86574.1 - 2.8e-19 67.4 13.0 0.053 13.6 0.1 9.3 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 EAQ86574.1 - 2.3e-18 66.0 12.6 0.0011 19.4 0.0 8.0 5 2 2 8 8 8 4 HEAT-like repeat Arm_2 PF04826.8 EAQ86574.1 - 1e-10 41.2 8.2 0.0035 16.4 0.1 3.5 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 EAQ86574.1 - 1e-10 40.5 7.2 1.2e-06 27.1 0.4 2.8 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 EAQ86574.1 - 2.6e-10 39.9 2.6 0.0011 18.2 0.1 3.6 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 EAQ86574.1 - 4.6e-10 38.0 0.9 8.6e-10 37.1 0.6 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.2 EAQ86574.1 - 0.004 17.0 4.0 16 5.3 0.0 4.3 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 EAQ86574.1 - 0.014 15.7 6.3 76 4.2 0.1 6.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAQ86574.1 - 0.034 14.5 0.2 0.99 9.8 0.1 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1981 PF09324.5 EAQ86574.1 - 0.083 12.4 0.0 9.6 5.8 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1981) CBS PF00571.23 EAQ86575.1 - 3e-31 106.9 8.3 5.2e-14 51.7 0.1 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.22 EAQ86576.1 - 0.00096 18.7 0.0 0.0044 16.6 0.0 1.9 1 1 1 2 2 2 1 RhoGAP domain PBP PF01161.15 EAQ86577.1 - 1.3e-11 44.5 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.17 EAQ86578.1 - 2.7e-44 150.8 0.0 3.6e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rox3 PF08633.5 EAQ86579.1 - 1.1e-69 234.6 4.7 3e-68 229.9 0.2 2.1 2 0 0 2 2 2 2 Rox3 mediator complex subunit PGAP1 PF07819.8 EAQ86580.1 - 2.3e-07 30.6 0.0 6.2e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EAQ86580.1 - 1.9e-06 27.3 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAQ86580.1 - 6.9e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ86580.1 - 0.00011 22.2 1.0 0.00049 20.0 0.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EAQ86580.1 - 0.01 15.5 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 EAQ86580.1 - 0.016 15.4 1.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain GAGA_bind PF06217.7 EAQ86580.1 - 0.016 15.1 2.7 0.035 14.0 1.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_pp85 PF04637.7 EAQ86580.1 - 0.083 11.1 4.3 3.9 5.6 1.9 2.2 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Abhydrolase_3 PF07859.8 EAQ86580.1 - 0.11 12.1 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EAQ86580.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) TMCO5 PF14992.1 EAQ86580.1 - 0.3 10.1 3.6 0.46 9.5 2.5 1.1 1 0 0 1 1 1 0 TMCO5 family ATP-grasp_2 PF08442.5 EAQ86581.1 - 6.5e-47 159.5 2.6 2.7e-27 95.4 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain Ligase_CoA PF00549.14 EAQ86581.1 - 1.8e-26 92.5 0.5 3.3e-26 91.7 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EAQ86581.1 - 2.3e-06 27.0 0.1 6.3e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EAQ86581.1 - 0.00089 18.8 0.1 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 EAQ86581.1 - 0.0054 15.8 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ATP-grasp_4 PF13535.1 EAQ86581.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain GlcNAc PF11397.3 EAQ86581.1 - 0.06 12.4 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) p450 PF00067.17 EAQ86583.1 - 1e-10 40.7 0.0 1.2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSF_DNA-bind PF00447.12 EAQ86584.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 HSF-type DNA-binding WD40 PF00400.27 EAQ86585.1 - 3.7e-27 93.1 3.2 1e-08 34.7 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 EAQ86585.1 - 9e-09 35.1 0.7 9e-09 35.1 0.5 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EAQ86585.1 - 3.2e-05 23.7 0.0 0.00026 20.7 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EAQ86585.1 - 0.00048 19.0 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.7 EAQ86585.1 - 0.0096 13.7 0.1 0.026 12.3 0.0 1.7 1 1 0 1 1 1 1 IKI3 family PD40 PF07676.7 EAQ86585.1 - 0.1 12.3 0.1 40 4.0 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MMS1_N PF10433.4 EAQ86585.1 - 0.12 10.5 0.0 1 7.3 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DNA_pol_alpha_N PF12254.3 EAQ86585.1 - 0.88 9.4 4.4 2.1 8.2 3.0 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.27 EAQ86587.1 - 1.5e-06 27.8 10.8 0.037 13.9 0.3 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF627 PF04781.7 EAQ86587.1 - 0.004 16.7 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF627) Sigma70_r1_2 PF00140.15 EAQ86587.1 - 0.014 15.0 1.0 0.026 14.1 0.7 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 PP1 PF07430.6 EAQ86587.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Phloem filament protein PP1 Ras PF00071.17 EAQ86589.1 - 1.5e-65 219.4 0.5 1.8e-65 219.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ86589.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ86589.1 - 2.7e-16 59.2 0.1 3.3e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ86589.1 - 1.2e-05 24.8 0.2 2.8e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ86589.1 - 1.7e-05 24.0 0.1 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ86589.1 - 7e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAQ86589.1 - 0.00043 19.5 0.0 0.00069 18.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EAQ86589.1 - 0.0006 19.1 0.1 0.0045 16.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 EAQ86589.1 - 0.0012 19.0 0.1 0.088 13.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ86589.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAQ86589.1 - 0.0091 15.1 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EAQ86589.1 - 0.017 14.1 0.1 0.21 10.5 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 EAQ86589.1 - 0.018 15.0 0.1 0.066 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EAQ86589.1 - 0.024 14.5 0.1 0.076 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAQ86589.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EAQ86589.1 - 0.059 13.0 0.0 0.096 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EAQ86589.1 - 0.093 13.0 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EAQ86589.1 - 0.094 12.2 0.1 0.53 9.7 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.27 EAQ86590.1 - 3.8e-33 112.1 1.8 1.7e-13 49.9 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 EAQ86590.1 - 2.9e-09 36.7 0.0 6.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ86590.1 - 1.3e-06 28.5 0.0 4.6e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 EAQ86590.1 - 0.00049 19.6 0.1 4.1 7.1 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 EAQ86590.1 - 0.004 16.2 0.7 0.0091 15.0 0.5 1.7 1 1 0 1 1 1 1 KAP family P-loop domain DUF746 PF05344.6 EAQ86590.1 - 0.029 13.8 0.0 0.4 10.2 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) HTH_IclR PF09339.5 EAQ86590.1 - 0.029 13.9 1.3 0.052 13.1 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain CENP-B_N PF04218.8 EAQ86590.1 - 0.036 13.4 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain AAA_22 PF13401.1 EAQ86590.1 - 0.042 13.9 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EAQ86590.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Herpes_capsid PF06112.6 EAQ86592.1 - 1.5 8.8 4.2 2.4 8.2 2.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Gly-zipper_OmpA PF13436.1 EAQ86592.1 - 1.7 8.3 10.4 2.7 7.6 7.2 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Carn_acyltransf PF00755.15 EAQ86594.1 - 2.3e-135 451.9 0.0 2.1e-113 379.4 0.0 3.0 3 0 0 3 3 3 3 Choline/Carnitine o-acyltransferase M_domain PF12938.2 EAQ86594.1 - 0.66 9.7 3.1 1.3 8.7 2.1 1.4 1 0 0 1 1 1 0 M domain of GW182 Glycophorin_A PF01102.13 EAQ86595.1 - 7.3e-05 22.5 2.3 0.00033 20.4 1.6 2.1 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.1 EAQ86595.1 - 0.0092 15.6 0.5 0.02 14.6 0.4 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF515 PF04415.7 EAQ86595.1 - 0.6 8.2 3.2 0.87 7.7 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Rad51 PF08423.6 EAQ86596.1 - 3.1e-14 52.4 0.0 4.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAQ86596.1 - 3.5e-11 42.8 0.0 6.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EAQ86596.1 - 2.1e-05 23.7 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EAQ86596.1 - 6.4e-05 22.1 0.0 0.00033 19.8 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein PAXNEB PF05625.6 EAQ86596.1 - 0.018 13.9 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein AAA_22 PF13401.1 EAQ86596.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb2_6 PF00562.23 EAQ86597.1 - 3.8e-113 378.1 0.0 5.4e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAQ86597.1 - 3.8e-47 159.8 0.0 5.9e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EAQ86597.1 - 3.6e-29 101.5 0.0 9.7e-29 100.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EAQ86597.1 - 6.9e-29 99.9 0.6 1.6e-28 98.7 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EAQ86597.1 - 8.2e-21 73.5 0.0 1.7e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EAQ86597.1 - 8.3e-19 67.1 0.0 2e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EAQ86597.1 - 1.2e-11 44.3 0.3 3.1e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pkinase PF00069.20 EAQ86598.1 - 2.6e-11 43.1 0.0 1.3e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain PUF PF00806.14 EAQ86600.1 - 3.9e-61 199.2 11.5 9e-08 31.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 EAQ86600.1 - 0.071 12.1 0.2 0.19 10.7 0.1 1.6 1 1 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Ribosomal_L15e PF00827.12 EAQ86601.1 - 2.8e-91 304.2 10.4 3.2e-91 304.0 7.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF1631 PF07793.6 EAQ86602.1 - 0.57 8.2 5.7 0.66 8.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PSP1 PF04468.7 EAQ86603.1 - 6.1e-31 106.2 0.8 1.2e-30 105.2 0.5 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EAQ86605.1 - 3.6e-28 97.0 0.0 8.4e-28 95.8 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EAQ86605.1 - 1.1e-20 73.0 0.1 1.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain RasGEF PF00617.14 EAQ86607.1 - 1.8e-44 151.7 0.2 2.6e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 EAQ86607.1 - 7.6e-14 52.2 0.0 1.7e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RasGEF_N PF00618.15 EAQ86607.1 - 7.6e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif GTP_EFTU PF00009.22 EAQ86607.1 - 0.00015 21.2 0.0 0.43 9.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.17 EAQ86607.1 - 0.0012 18.2 0.0 0.044 13.1 0.0 2.3 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.22 EAQ86607.1 - 0.0085 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EAQ86607.1 - 0.012 15.6 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EAQ86607.1 - 0.015 15.4 0.0 0.13 12.3 0.0 2.5 4 0 0 4 4 2 0 AAA domain AAA_17 PF13207.1 EAQ86607.1 - 0.029 15.1 0.0 0.12 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAQ86607.1 - 0.032 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IIGP PF05049.8 EAQ86607.1 - 0.039 12.7 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EAQ86607.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EAQ86607.1 - 0.063 12.7 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EAQ86607.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ86607.1 - 0.094 13.0 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ86607.1 - 0.16 11.4 0.0 0.65 9.5 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EAQ86607.1 - 0.2 11.1 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EAQ86607.1 - 0.27 9.8 0.0 0.46 9.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SLAC1 PF03595.12 EAQ86608.1 - 2.9e-45 154.3 17.8 3.3e-45 154.1 12.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF202 PF02656.10 EAQ86608.1 - 0.0086 16.2 2.7 0.14 12.3 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF3609 PF12259.3 EAQ86608.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Pribosyl_synth PF14572.1 EAQ86609.1 - 4.8e-38 130.7 0.8 2.1e-34 118.8 0.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EAQ86609.1 - 2.6e-28 98.0 0.0 6.3e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EAQ86609.1 - 1.6e-11 44.0 0.7 4.6e-11 42.5 0.5 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EAQ86609.1 - 0.0026 16.9 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RNA_pol_Rpb4 PF03874.11 EAQ86610.1 - 4.2e-25 88.0 0.8 5.6e-25 87.6 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 PseudoU_synth_1 PF01416.15 EAQ86611.1 - 3.2e-26 91.7 0.0 2.9e-22 79.0 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF2076 PF09849.4 EAQ86611.1 - 0.038 14.0 0.9 0.06 13.4 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAP PF07174.6 EAQ86611.1 - 2.3 7.4 22.2 3.9 6.6 15.0 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Ndc1_Nup PF09531.5 EAQ86611.1 - 3 6.1 9.3 4.8 5.4 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.5 EAQ86611.1 - 4.3 6.4 16.1 6.5 5.8 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIG-H PF10181.4 EAQ86612.1 - 1.5e-27 94.9 0.0 2.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Serglycin PF04360.7 EAQ86612.1 - 0.067 12.9 1.7 0.1 12.3 1.2 1.3 1 0 0 1 1 1 0 Serglycin CENP-U PF13097.1 EAQ86615.1 - 0.1 12.4 4.2 0.12 12.2 2.9 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Snf7 PF03357.16 EAQ86616.1 - 8.6e-23 80.5 2.5 8.6e-23 80.5 1.7 2.0 1 1 1 2 2 2 1 Snf7 DivIVA PF05103.8 EAQ86616.1 - 0.017 15.2 1.8 0.017 15.2 1.3 2.8 2 1 0 2 2 2 0 DivIVA protein DUF1509 PF07420.6 EAQ86616.1 - 0.093 11.9 0.8 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) MetJ PF01340.15 EAQ86616.1 - 0.11 12.2 0.3 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Met Apo-repressor, MetJ MAT1 PF06391.8 EAQ86616.1 - 0.17 11.4 10.0 0.054 13.0 1.6 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Glyco_hydro_43 PF04616.9 EAQ86618.1 - 1.9e-36 125.6 5.8 2.7e-36 125.1 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CTP_transf_2 PF01467.21 EAQ86618.1 - 1.3e-05 25.3 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Glyco_hydro_61 PF03443.9 EAQ86619.1 - 2.2e-30 106.0 0.0 2.8e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PARP PF00644.15 EAQ86621.1 - 1.6e-11 44.0 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EAQ86621.1 - 5e-08 32.4 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ86621.1 - 0.00042 20.0 0.0 0.0019 17.9 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic E2 family B COG5 PF10392.4 EAQ86622.1 - 0.0014 18.5 0.4 0.0027 17.6 0.0 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 NUDIX PF00293.23 EAQ86623.1 - 7.5e-09 35.3 0.1 1.1e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.4 EAQ86623.1 - 0.0023 17.4 3.7 0.0029 17.1 2.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ATE_C PF04377.10 EAQ86624.1 - 1.8e-43 147.6 0.0 2.8e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EAQ86624.1 - 0.0011 18.7 0.4 0.0011 18.7 0.3 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus DUF3359 PF11839.3 EAQ86624.1 - 2.5 8.4 6.4 4.6 7.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Ribosomal_S5_C PF03719.10 EAQ86626.1 - 3.4e-18 64.6 0.0 7.4e-18 63.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EAQ86626.1 - 6.1e-08 32.2 0.1 1.2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF676 PF05057.9 EAQ86627.1 - 3.9e-06 26.3 0.0 7.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EAQ86627.1 - 2.5e-05 23.9 0.0 6.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 EAQ86627.1 - 0.028 14.5 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAQ86627.1 - 0.037 14.0 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EAQ86627.1 - 0.046 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EAQ86627.1 - 0.081 13.1 1.5 0.7 10.0 1.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) LCAT PF02450.10 EAQ86627.1 - 0.1 11.5 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Torsin PF06309.6 EAQ86627.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 Torsin Ank_2 PF12796.2 EAQ86628.1 - 2.7e-40 136.6 0.5 1.1e-18 67.3 0.3 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86628.1 - 4.3e-32 108.3 5.2 9.1e-10 37.8 0.5 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EAQ86628.1 - 8.3e-25 86.6 1.0 1.5e-09 38.1 0.2 5.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ86628.1 - 2.2e-23 81.7 4.1 6.3e-10 38.9 0.5 6.3 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86628.1 - 2.3e-19 67.5 0.9 7.9e-05 22.5 0.1 7.3 7 0 0 7 7 7 3 Ankyrin repeat AAA_22 PF13401.1 EAQ86628.1 - 6.4e-06 26.3 0.1 2.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ86628.1 - 8e-05 22.6 0.0 0.00037 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EAQ86628.1 - 0.00024 20.7 0.1 0.00097 18.8 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EAQ86628.1 - 0.0059 16.3 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EAQ86628.1 - 0.0097 15.3 0.0 0.08 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EAQ86628.1 - 0.051 12.5 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pec_lyase_N PF04431.8 EAQ86629.1 - 0.0051 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Pectate lyase, N terminus AAA_13 PF13166.1 EAQ86629.1 - 0.078 11.4 16.7 0.11 10.9 11.6 1.1 1 0 0 1 1 1 0 AAA domain DUF4404 PF14357.1 EAQ86629.1 - 0.22 11.9 5.9 1.1 9.7 4.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Borrelia_P83 PF05262.6 EAQ86629.1 - 2 6.5 25.9 2.7 6.1 18.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 EAQ86631.1 - 9.3e-62 208.5 0.0 1.2e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86631.1 - 7e-25 87.5 0.0 9.7e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ86631.1 - 0.03 13.3 0.0 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like MCR_beta PF02241.13 EAQ86631.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain zf-C2H2_4 PF13894.1 EAQ86632.1 - 0.13 12.6 0.2 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 EAQ86633.1 - 8e-16 58.4 1.5 1.3e-15 57.7 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ86633.1 - 1.4e-07 31.3 0.3 2.1e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ86633.1 - 6e-06 26.2 0.0 7.5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EAQ86633.1 - 0.053 12.7 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family zf-CCCH PF00642.19 EAQ86634.1 - 5.5e-06 25.9 1.0 5.5e-06 25.9 0.7 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EAQ86635.1 - 1e-14 53.9 0.0 1.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ86635.1 - 6.8e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ86635.1 - 6.3e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EAQ86635.1 - 0.0028 18.0 0.7 0.0028 18.0 0.5 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 EAQ86635.1 - 0.0063 16.5 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family Ribosomal_60s PF00428.14 EAQ86635.1 - 1.1 9.6 17.0 3.2 8.2 0.5 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein RNase_PH PF01138.16 EAQ86636.1 - 5.9e-10 39.5 0.0 1.5e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Enkurin PF13864.1 EAQ86637.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Calmodulin-binding Ribosomal_60s PF00428.14 EAQ86637.1 - 0.51 10.7 6.9 1.3 9.4 4.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cytochrom_C PF00034.16 EAQ86638.1 - 1.1e-10 42.1 0.0 1.6e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EAQ86638.1 - 4.4e-09 36.3 2.0 2e-08 34.2 1.4 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EAQ86638.1 - 0.0037 16.7 0.3 0.031 13.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain AAA PF00004.24 EAQ86639.1 - 1.4e-65 219.4 0.0 1.8e-46 157.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAQ86639.1 - 4.5e-07 29.9 0.0 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EAQ86639.1 - 4.6e-06 25.8 0.0 0.00032 19.8 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAQ86639.1 - 5.6e-06 26.1 0.1 0.056 13.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAQ86639.1 - 2.8e-05 24.2 0.1 0.0034 17.5 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EAQ86639.1 - 3.8e-05 23.7 0.8 0.002 18.1 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EAQ86639.1 - 0.00037 19.6 0.0 0.0025 16.9 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EAQ86639.1 - 0.00037 20.3 0.0 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAQ86639.1 - 0.0023 17.3 1.8 6.6 6.0 0.1 3.5 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 EAQ86639.1 - 0.0027 17.3 0.2 0.03 14.0 0.1 2.8 2 1 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 EAQ86639.1 - 0.0042 16.0 0.0 0.0095 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EAQ86639.1 - 0.0045 16.8 0.2 0.022 14.6 0.0 2.3 4 0 0 4 4 1 1 AAA domain AAA_17 PF13207.1 EAQ86639.1 - 0.0097 16.7 0.0 0.026 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 EAQ86639.1 - 0.018 14.8 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.12 EAQ86639.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAQ86639.1 - 0.032 13.4 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EAQ86639.1 - 0.043 12.5 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EAQ86639.1 - 0.044 13.9 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EAQ86639.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EAQ86639.1 - 0.094 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EAQ86639.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EAQ86639.1 - 0.13 12.5 0.0 0.46 10.7 0.0 1.8 1 1 1 2 2 2 0 ABC transporter Rad17 PF03215.10 EAQ86639.1 - 0.3 9.6 0.0 0.44 9.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Pkinase PF00069.20 EAQ86640.1 - 3e-19 69.1 0.0 3.7e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86640.1 - 2.3e-08 33.4 0.0 2.9e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ86640.1 - 0.00071 19.3 0.0 0.00077 19.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAQ86640.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Mito_carr PF00153.22 EAQ86641.1 - 1e-44 150.1 7.7 8e-17 60.7 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR PF05347.10 EAQ86642.1 - 1.8e-06 27.6 0.5 1.8e-06 27.6 0.3 2.1 2 1 1 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ86642.1 - 0.064 13.4 0.5 0.064 13.4 0.3 1.7 2 0 0 2 2 2 0 Complex1_LYR-like Sugar_tr PF00083.19 EAQ86643.1 - 3.6e-93 312.6 8.4 4.4e-93 312.3 5.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ86643.1 - 1.7e-26 92.7 46.9 5.4e-24 84.5 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ86643.1 - 2.4e-09 36.0 15.0 1.7e-05 23.3 0.3 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 EAQ86643.1 - 0.0054 15.4 0.3 0.0054 15.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF791) UNC-93 PF05978.11 EAQ86643.1 - 0.032 13.7 5.3 0.87 9.0 0.4 2.4 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 GD_AH_C PF04295.8 EAQ86643.1 - 0.036 12.7 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus MFS_3 PF05977.8 EAQ86643.1 - 0.32 9.0 5.1 0.15 10.1 0.7 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 EAQ86644.1 - 5.8e-109 363.5 2.9 6.9e-109 363.3 2.0 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit YajC PF02699.10 EAQ86644.1 - 3.4 7.3 0.0 3.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Preprotein translocase subunit Cytochrom_B561 PF03188.11 EAQ86645.1 - 6.8e-16 58.3 8.1 6.8e-16 58.3 5.6 1.8 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EAQ86645.1 - 0.0029 17.2 0.6 0.0029 17.2 0.4 2.9 2 0 0 2 2 2 1 PepSY-associated TM helix DUF4079 PF13301.1 EAQ86645.1 - 0.0061 16.5 16.2 0.45 10.5 0.3 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) Ferric_reduct PF01794.14 EAQ86645.1 - 0.01 15.9 4.8 0.01 15.9 3.3 2.7 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Allantoicase PF03561.10 EAQ86646.1 - 1.2e-104 346.2 0.2 2.1e-57 192.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.2 EAQ86647.1 - 2.4e-18 66.2 0.1 6.4e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86647.1 - 1.2e-16 59.5 0.0 5.4e-07 29.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EAQ86647.1 - 2.9e-15 56.3 0.5 3.5e-07 30.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ86647.1 - 1.8e-12 47.0 0.0 5.4e-08 32.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86647.1 - 2.7e-10 39.4 0.1 0.0097 16.0 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat RabGAP-TBC PF00566.13 EAQ86648.1 - 8.3e-32 110.3 0.0 1.4e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2722 PF10846.3 EAQ86650.1 - 2.5e-07 30.0 9.8 2.7e-06 26.6 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) HATPase_c PF02518.21 EAQ86652.1 - 4.7e-23 81.0 0.1 8.9e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EAQ86652.1 - 1.1e-21 76.6 0.1 3.6e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EAQ86652.1 - 8.8e-20 70.7 0.0 4e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 EAQ86652.1 - 3.3e-15 55.9 0.5 5.7e-10 39.1 0.3 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EAQ86652.1 - 6.1e-13 49.0 0.0 1.2e-07 32.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EAQ86652.1 - 1.1e-08 34.7 0.0 0.0075 16.0 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EAQ86652.1 - 1.5e-08 34.6 0.1 8.5e-07 28.9 0.1 3.0 2 0 0 2 2 2 1 PAS fold PAS_10 PF13596.1 EAQ86652.1 - 0.21 11.8 0.0 0.59 10.4 0.0 1.8 1 0 0 1 1 1 0 PAS domain Serglycin PF04360.7 EAQ86652.1 - 2.3 7.9 8.1 1.3 8.7 2.1 2.5 2 0 0 2 2 2 0 Serglycin Collagen PF01391.13 EAQ86654.1 - 0.013 14.9 8.0 0.022 14.2 5.6 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ssl1 PF04056.9 EAQ86655.1 - 2.4e-68 229.5 0.0 3.3e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EAQ86655.1 - 8.6e-17 60.8 4.3 8.6e-17 60.8 3.0 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EAQ86655.1 - 4.5e-08 33.4 0.0 8.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 EAQ86655.1 - 0.024 14.5 1.6 0.024 14.5 1.1 2.5 3 0 0 3 3 3 0 IBR domain Glyoxalase PF00903.20 EAQ86656.1 - 1.7e-22 79.7 0.3 1.4e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EAQ86656.1 - 6.6e-14 51.8 0.1 4.3e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EAQ86656.1 - 4.3e-13 49.8 0.1 2.8e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EAQ86656.1 - 6.6e-06 26.1 0.0 0.038 13.9 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EAQ86656.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_11 PF13414.1 EAQ86657.1 - 0.026 14.1 0.5 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 TPR repeat Ribosomal_L27e PF01777.13 EAQ86658.1 - 2e-37 127.1 5.3 2.7e-37 126.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EAQ86658.1 - 0.0098 15.5 0.1 0.031 14.0 0.1 1.8 1 0 0 1 1 1 1 KOW motif DUF1922 PF09082.5 EAQ86658.1 - 0.032 14.2 0.1 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) ECM11 PF15463.1 EAQ86658.1 - 0.22 11.8 1.5 0.28 11.4 0.2 1.7 2 0 0 2 2 2 0 Extracellular mutant protein 11 TPT PF03151.11 EAQ86659.1 - 1.8e-20 73.1 10.0 1.8e-20 73.1 7.0 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family NAD_binding_8 PF13450.1 EAQ86660.1 - 2.7e-08 33.6 0.1 5.5e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EAQ86660.1 - 6.3e-06 25.5 0.0 4.9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EAQ86660.1 - 0.00023 21.2 0.2 0.00061 19.9 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ86660.1 - 0.00092 19.1 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ86660.1 - 0.0058 15.7 0.1 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EAQ86660.1 - 0.026 12.9 0.1 0.041 12.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EAQ86660.1 - 0.062 12.3 0.4 0.14 11.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EAQ86660.1 - 0.097 11.5 0.5 0.25 10.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EAQ86660.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 EAQ86660.1 - 0.15 10.9 0.0 0.93 8.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HATPase_c PF02518.21 EAQ86661.1 - 1.8e-28 98.4 0.1 1.2e-27 95.7 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAQ86661.1 - 1.1e-19 70.4 0.1 2.9e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EAQ86661.1 - 1.3e-19 69.9 0.4 3.8e-19 68.4 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EAQ86661.1 - 1.2e-09 38.7 0.0 3.6e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EAQ86661.1 - 2e-08 34.4 0.0 4.7e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EAQ86661.1 - 1e-05 25.5 1.0 0.00039 20.4 0.7 3.0 1 1 0 1 1 1 1 AAA ATPase domain HATPase_c_3 PF13589.1 EAQ86661.1 - 0.00019 21.1 0.0 0.00046 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 EAQ86661.1 - 0.00024 20.6 5.8 0.017 14.7 0.2 4.2 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.1 EAQ86661.1 - 0.003 17.4 5.9 0.17 11.8 0.5 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ86661.1 - 0.038 13.7 0.1 0.92 9.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GET2 PF08690.5 EAQ86662.1 - 1e-12 47.9 0.0 2e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 GET complex subunit GET2 WD40 PF00400.27 EAQ86663.1 - 5.8e-22 76.7 6.4 2.8e-05 23.7 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 EAQ86663.1 - 4.5e-12 45.9 0.7 1.9e-11 43.9 0.5 2.2 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EAQ86663.1 - 7.7e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 RRM_1 PF00076.17 EAQ86664.1 - 1.8e-18 65.9 0.0 2.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ86664.1 - 3.3e-15 55.8 0.0 5.4e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ86664.1 - 3e-10 39.7 0.0 5.4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAQ86664.1 - 0.038 13.7 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.1 EAQ86664.1 - 0.045 13.5 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif B12D PF06522.6 EAQ86665.1 - 5.3e-07 29.2 0.0 8.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 EAQ86666.1 - 7.4e-18 64.3 3.7 8.4e-18 64.1 2.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EAQ86666.1 - 0.0029 16.9 0.3 0.004 16.5 0.2 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 EAQ86666.1 - 0.07 12.5 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Telomere_Sde2 PF13019.1 EAQ86667.1 - 2.1e-64 216.0 0.3 3.1e-64 215.5 0.2 1.3 1 0 0 1 1 1 1 Telomere stability and silencing S10_plectin PF03501.10 EAQ86668.1 - 6e-37 125.3 0.2 7.2e-37 125.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.7 EAQ86669.1 - 2.7e-24 85.0 0.4 7.6e-24 83.5 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ86669.1 - 3.8e-13 49.1 0.0 5.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ86669.1 - 1.7e-05 25.6 0.0 3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gp_dh_N PF00044.19 EAQ86669.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Syndecan PF01034.15 EAQ86670.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain OB_NTP_bind PF07717.11 EAQ86671.1 - 1.8e-24 85.7 0.0 3.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAQ86671.1 - 6.5e-21 74.2 0.1 1.4e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAQ86671.1 - 2.7e-07 30.3 0.0 6.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAQ86671.1 - 5.4e-05 23.3 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EAQ86671.1 - 0.004 16.6 0.3 0.015 14.7 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EAQ86671.1 - 0.016 14.7 0.1 0.04 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EAQ86671.1 - 0.023 13.8 0.1 0.07 12.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EAQ86671.1 - 0.029 14.2 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAQ86671.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ86671.1 - 0.28 11.4 1.0 0.77 10.0 0.1 2.0 2 1 0 3 3 3 0 ABC transporter DUF2293 PF10056.4 EAQ86672.1 - 2.7e-29 100.9 0.2 1.3e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Snf7 PF03357.16 EAQ86673.1 - 1.1e-13 50.9 2.3 1.5e-13 50.4 1.6 1.2 1 0 0 1 1 1 1 Snf7 CUE PF02845.11 EAQ86674.1 - 5e-14 51.4 0.0 9e-14 50.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain HUN PF08729.5 EAQ86674.1 - 0.02 14.7 0.2 0.02 14.7 0.1 2.4 2 1 0 2 2 2 0 HPC2 and ubinuclein domain Ank_2 PF12796.2 EAQ86675.1 - 4.2e-51 171.2 12.3 2.2e-14 53.5 0.1 5.1 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) SPX PF03105.14 EAQ86675.1 - 1.9e-29 103.2 10.8 5.7e-17 62.4 1.8 2.2 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 EAQ86675.1 - 1.4e-24 86.0 8.7 2e-08 34.5 0.0 6.0 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 EAQ86675.1 - 3.2e-24 83.4 14.2 2.9e-05 23.6 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EAQ86675.1 - 3e-19 68.6 11.1 1.5e-05 25.0 0.1 7.4 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86675.1 - 5.1e-19 66.4 8.6 0.0039 17.3 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat GDPD PF03009.12 EAQ86675.1 - 3e-10 40.0 0.0 1.8e-09 37.4 0.0 2.2 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.1 EAQ86675.1 - 0.098 11.9 1.6 1.4 8.2 0.1 2.8 2 0 0 2 2 2 0 Ribosome-assembly protein 3 RVP PF00077.15 EAQ86675.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Serglycin PF04360.7 EAQ86676.1 - 1.5 8.5 8.9 1.6 8.4 6.1 1.4 1 1 0 1 1 1 0 Serglycin DUF2919 PF11143.3 EAQ86677.1 - 0.078 12.8 3.6 0.18 11.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF1191 PF06697.7 EAQ86677.1 - 0.11 11.2 0.5 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Tetraspannin PF00335.15 EAQ86677.1 - 0.96 8.6 6.5 0.048 12.9 0.7 1.7 2 1 1 3 3 3 0 Tetraspanin family DUF1056 PF06341.6 EAQ86677.1 - 1.2 9.1 8.9 0.12 12.4 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Coa1 PF08695.5 EAQ86678.1 - 1.4e-39 134.2 0.0 1.9e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Class_IIIsignal PF04021.7 EAQ86678.1 - 0.1 12.3 0.5 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Class III signal peptide RNA_pol_Rpb2_5 PF04567.12 EAQ86678.1 - 0.1 12.5 0.3 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Ribosomal_L3 PF00297.17 EAQ86679.1 - 9.1e-30 103.9 0.7 1.8e-29 102.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L3 RsgI_N PF12791.2 EAQ86680.1 - 0.22 11.2 1.1 0.99 9.1 0.7 2.1 1 1 0 1 1 1 0 Anti-sigma factor N-terminus PITH PF06201.8 EAQ86681.1 - 3e-44 150.4 0.0 3.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.4 EAQ86682.1 - 6.7e-81 272.5 0.0 1.6e-66 224.9 0.0 2.8 2 1 1 3 3 3 2 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EAQ86683.1 - 6.3e-22 77.3 0.2 1.8e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Toxin_62 PF15540.1 EAQ86683.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 62 Atg14 PF10186.4 EAQ86683.1 - 0.89 8.4 13.3 0.12 11.2 6.5 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EAQ86683.1 - 1.8 6.8 6.1 2.1 6.6 4.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 EAQ86683.1 - 2.7 7.8 17.1 1.3 8.9 4.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Peripla_BP_2 PF01497.13 EAQ86683.1 - 3.7 6.6 9.2 0.5 9.4 3.6 1.5 2 0 0 2 2 2 0 Periplasmic binding protein zinc_ribbon_6 PF14599.1 EAQ86684.1 - 8.8e-25 86.2 3.3 8.8e-25 86.2 2.3 3.5 3 2 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EAQ86684.1 - 2.4e-15 56.4 23.4 2.4e-15 56.4 16.2 4.3 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EAQ86684.1 - 4.3e-08 32.8 5.6 4.3e-08 32.8 3.9 4.7 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ86684.1 - 2.4e-07 30.6 7.0 2.4e-07 30.6 4.9 5.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ86684.1 - 0.00011 21.9 7.3 0.00011 21.9 5.1 6.1 5 2 1 6 6 6 1 zinc-RING finger domain CDC27 PF09507.5 EAQ86684.1 - 0.0033 16.7 9.0 0.0056 15.9 6.2 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 MOZART1 PF12554.3 EAQ86685.1 - 2e-25 88.0 1.1 2.4e-25 87.7 0.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Transferase PF02458.10 EAQ86689.1 - 0.00072 18.1 0.0 0.025 13.0 0.0 2.8 3 0 0 3 3 3 1 Transferase family PucR PF07905.6 EAQ86689.1 - 0.053 13.1 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family PNRC PF15365.1 EAQ86690.1 - 0.11 12.5 3.2 0.22 11.5 2.2 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Ecl1 PF12855.2 EAQ86691.1 - 8.2e-08 31.4 1.7 1.5e-07 30.5 1.2 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EAQ86691.1 - 0.025 14.4 2.4 0.067 13.0 1.6 1.7 1 0 0 1 1 1 0 MYND finger His_Phos_1 PF00300.17 EAQ86694.1 - 5.9e-31 107.6 0.5 1.1e-30 106.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EAQ86694.1 - 0.00061 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1168 PF06658.7 EAQ86695.1 - 1.3e-39 134.9 14.0 2.1e-39 134.3 9.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Cpn60_TCP1 PF00118.19 EAQ86696.1 - 4.8e-161 536.6 0.4 5.4e-161 536.4 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SKG6 PF08693.5 EAQ86697.1 - 2.9e-09 36.0 0.7 5.5e-09 35.1 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EAQ86697.1 - 3.8e-05 23.4 0.8 6.5e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 TMEM154 protein family TMEM51 PF15345.1 EAQ86697.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 CcmD PF04995.9 EAQ86697.1 - 0.013 15.1 2.4 0.023 14.4 1.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4448 PF14610.1 EAQ86697.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Trp_oprn_chp PF09534.5 EAQ86697.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.1 EAQ86697.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PAT1 PF09770.4 EAQ86697.1 - 3.7 5.6 6.9 4.4 5.4 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2615 PF11027.3 EAQ86697.1 - 5.6 6.9 0.0 5.6 6.9 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) HECT PF00632.20 EAQ86698.1 - 3.1e-23 82.4 0.0 5.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 EAQ86698.1 - 0.0031 17.2 0.6 0.0075 15.9 0.4 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CRM1_C PF08767.6 EAQ86700.1 - 3.3e-116 387.6 2.3 3.3e-116 387.6 1.6 2.7 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EAQ86700.1 - 1.5e-41 141.7 6.9 1.5e-41 141.7 4.8 3.3 3 1 0 3 3 3 1 Exportin 1-like protein Aminotran_5 PF00266.14 EAQ86701.1 - 1.3e-26 93.2 0.0 1.6e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EAQ86701.1 - 0.0079 16.0 0.2 0.027 14.3 0.0 2.0 2 1 0 2 2 2 1 B12 binding domain Metallophos_2 PF12850.2 EAQ86702.1 - 2.6e-11 43.5 0.0 3.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ86702.1 - 0.0094 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Shugoshin_N PF07558.6 EAQ86703.1 - 1.6e-15 56.4 3.0 1.6e-15 56.4 2.1 2.0 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EAQ86703.1 - 1.3e-11 43.6 5.0 1.3e-11 43.6 3.4 3.7 4 0 0 4 4 4 1 Shugoshin C terminus AKNA PF12443.3 EAQ86703.1 - 0.044 13.7 4.3 0.049 13.6 1.2 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor DASH_Dad2 PF08654.5 EAQ86704.1 - 5.4e-17 61.6 5.8 1.6e-14 53.7 2.0 2.1 1 1 1 2 2 2 2 DASH complex subunit Dad2 HSCB_C PF07743.8 EAQ86704.1 - 0.048 14.1 1.6 0.077 13.4 1.1 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain COesterase PF00135.23 EAQ86706.1 - 2.9e-66 224.3 0.0 2e-63 214.9 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ86706.1 - 3e-07 30.2 0.3 1e-06 28.4 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ86706.1 - 0.0081 15.9 1.7 0.01 15.5 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family HLH PF00010.21 EAQ86708.1 - 0.00033 20.2 0.4 0.0014 18.2 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IMS PF00817.15 EAQ86709.1 - 1.1e-32 112.8 0.0 1.7e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EAQ86709.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EAQ86709.1 - 0.00082 19.2 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Filo_glycop PF01611.11 EAQ86710.1 - 0.066 11.9 0.5 0.11 11.2 0.3 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein DUF1421 PF07223.6 EAQ86710.1 - 3.3 7.3 55.8 0.17 11.6 32.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1421) C2 PF00168.25 EAQ86711.1 - 9.8e-21 73.4 0.0 1e-13 50.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain DOCK-C2 PF14429.1 EAQ86711.1 - 0.19 11.3 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins ChpXY PF10216.4 EAQ86711.1 - 0.42 9.4 0.0 0.74 8.6 0.0 1.2 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) AAA_17 PF13207.1 EAQ86713.1 - 4.1e-06 27.6 0.0 1.4e-05 25.8 0.0 1.8 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EAQ86713.1 - 9.1e-05 22.7 0.0 0.00065 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EAQ86713.1 - 0.00062 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EAQ86713.1 - 0.0051 16.3 0.0 0.014 14.9 0.0 1.7 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EAQ86713.1 - 0.0078 16.1 0.0 0.015 15.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ86713.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_hydro_15 PF00723.16 EAQ86714.1 - 2.3e-83 280.2 0.0 2.6e-44 151.5 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EAQ86714.1 - 7.1e-21 73.6 0.2 2.1e-20 72.0 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.8 EAQ86715.1 - 8.1e-175 582.6 47.7 9.3e-175 582.4 33.1 1.0 1 0 0 1 1 1 1 SART-1 family PTH2 PF01981.11 EAQ86716.1 - 5.2e-47 158.3 0.5 6.8e-47 157.9 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 APH_6_hur PF04655.9 EAQ86716.1 - 0.032 13.4 0.3 0.048 12.7 0.2 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase BING4CT PF08149.6 EAQ86717.1 - 8.2e-40 134.1 0.0 6.6e-37 124.8 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EAQ86717.1 - 1.1e-07 31.5 0.0 1.5e-05 24.6 0.0 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EAQ86717.1 - 0.052 12.9 0.0 0.2 11.1 0.0 2.0 1 1 0 1 1 1 0 PQQ-like domain DUF663 PF04950.7 EAQ86718.1 - 1.1e-100 336.4 0.0 1.7e-100 335.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EAQ86718.1 - 6.5e-20 70.4 0.0 1.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 EAQ86719.1 - 3.2e-30 104.9 0.0 4.1e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EAQ86719.1 - 2.5e-05 23.2 0.8 0.00013 20.8 0.6 1.8 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EAQ86719.1 - 0.0033 17.3 0.0 0.011 15.6 0.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EAQ86719.1 - 0.05 13.0 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Mito_fiss_Elm1 PF06258.6 EAQ86719.1 - 0.057 12.3 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 PRK PF00485.13 EAQ86719.1 - 0.057 12.9 0.1 0.14 11.7 0.0 1.5 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 EAQ86719.1 - 0.068 12.7 0.2 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EAQ86719.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ86719.1 - 0.095 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 EAQ86719.1 - 0.097 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 EAQ86719.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase CoaE PF01121.15 EAQ86719.1 - 0.15 11.4 0.0 0.95 8.8 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase DUF4066 PF13278.1 EAQ86720.1 - 1.2e-27 96.1 0.0 1.7e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ86720.1 - 3.9e-10 39.3 0.0 5.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EAQ86720.1 - 0.078 12.4 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Chromo PF00385.19 EAQ86721.1 - 1.9e-08 33.8 0.2 4.6e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EAQ86721.1 - 0.0074 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Ras PF00071.17 EAQ86722.1 - 3.2e-38 130.6 0.0 6e-38 129.7 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EAQ86722.1 - 4.3e-12 46.5 0.0 6.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ86722.1 - 6.7e-08 31.9 0.0 7.5e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ86722.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SpoIIID PF12116.3 EAQ86722.1 - 0.092 12.6 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D Brix PF04427.13 EAQ86723.1 - 2.9e-34 118.4 0.0 3.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.2 EAQ86724.1 - 0.00038 20.1 0.2 0.00099 18.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ86724.1 - 0.052 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain Hist_deacetyl PF00850.14 EAQ86725.1 - 2.4e-87 293.1 0.0 3.9e-87 292.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EAQ86725.1 - 1.4e-40 138.6 0.1 2.5e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain Gp_dh_C PF02800.15 EAQ86727.1 - 2.7e-77 257.6 0.0 4e-77 257.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EAQ86727.1 - 6.7e-60 201.4 0.2 1.1e-59 200.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EAQ86727.1 - 0.0016 18.3 0.1 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus tRNA-synt_1d PF00750.14 EAQ86728.1 - 0.031 13.1 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) PAPA-1 PF04795.7 EAQ86731.1 - 5.3e-27 94.3 0.5 5.3e-27 94.3 0.4 4.1 3 1 1 4 4 4 1 PAPA-1-like conserved region Pex14_N PF04695.8 EAQ86732.1 - 9.3e-26 90.4 0.0 9.3e-26 90.4 0.0 3.3 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec8_exocyst PF04048.9 EAQ86732.1 - 0.038 13.6 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain HisKA_3 PF07730.8 EAQ86732.1 - 0.5 10.7 5.0 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 Histidine kinase DUF4050 PF13259.1 EAQ86733.1 - 1.9e-19 69.7 0.0 8.6e-19 67.6 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) DUF515 PF04415.7 EAQ86733.1 - 3 5.9 3.3 5.4 5.1 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) KAR9 PF08580.5 EAQ86733.1 - 8.6 4.4 9.4 13 3.8 6.5 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPX PF03105.14 EAQ86734.1 - 6.6e-49 167.1 0.1 1.5e-48 165.9 0.1 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EAQ86734.1 - 8.3e-35 120.5 37.1 1.6e-34 119.6 25.7 1.5 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EAQ86734.1 - 7e-13 47.8 44.2 2.3e-10 39.6 18.1 2.9 1 1 2 3 3 3 3 Citrate transporter RFX_DNA_binding PF02257.10 EAQ86734.1 - 9.2 6.4 6.4 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 RFX DNA-binding domain RTA1 PF04479.8 EAQ86735.1 - 3.1e-41 141.3 6.6 4.5e-41 140.7 4.6 1.2 1 0 0 1 1 1 1 RTA1 like protein SAYSvFN PF10260.4 EAQ86735.1 - 0.79 9.5 3.8 1.4 8.7 0.4 2.5 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Vps39_1 PF10366.4 EAQ86736.1 - 6.3e-32 109.8 0.0 3.8e-31 107.3 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EAQ86736.1 - 1.9e-17 63.6 0.0 4.8e-17 62.2 0.0 1.6 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EAQ86736.1 - 1.4e-11 44.5 0.0 3.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Lactamase_B_5 PF14597.1 EAQ86736.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily TPR_1 PF00515.23 EAQ86736.1 - 0.3 10.7 1.6 11 5.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 EAQ86736.1 - 0.36 10.4 1.6 17 5.0 0.1 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS Gon7 PF08738.5 EAQ86737.1 - 2e-17 63.0 6.3 5e-17 61.7 4.4 1.6 1 1 0 1 1 1 1 Gon7 family RNA_pol_3_Rpc31 PF11705.3 EAQ86737.1 - 0.019 14.9 2.8 0.019 14.8 1.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Phage_GPL PF05926.6 EAQ86737.1 - 0.069 12.9 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) KR PF08659.5 EAQ86737.1 - 0.081 12.5 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 KR domain Mig-14 PF07395.6 EAQ86737.1 - 0.097 11.6 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Mig-14 Acyl-thio_N PF12590.3 EAQ86737.1 - 0.12 12.8 0.3 0.15 12.5 0.2 1.2 1 0 0 1 1 1 0 Acyl-ATP thioesterase GCOM2 PF15328.1 EAQ86737.1 - 0.79 9.4 7.2 0.13 11.9 2.8 1.3 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 DUF4407 PF14362.1 EAQ86737.1 - 6.2 5.6 6.8 7.2 5.4 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HbrB PF08539.6 EAQ86738.1 - 1.1e-60 204.0 0.0 1.7e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Neur_chan_memb PF02932.11 EAQ86738.1 - 1.8 8.4 6.8 5.7 6.7 4.7 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LIM_bind PF01803.11 EAQ86739.1 - 1.6e-79 266.4 0.0 1.6e-79 266.4 0.0 5.7 3 1 2 5 5 5 1 LIM-domain binding protein Atg8 PF02991.11 EAQ86740.1 - 2.4e-51 172.0 0.2 2.8e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EAQ86740.1 - 3.5e-06 27.1 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 EAQ86741.1 - 9.9e-134 444.5 0.1 1.1e-133 444.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF876 PF05936.7 EAQ86741.1 - 0.042 12.2 0.0 0.061 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) MitMem_reg PF13012.1 EAQ86742.1 - 9.8e-39 132.0 0.3 2.6e-38 130.6 0.1 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EAQ86742.1 - 5.2e-29 100.2 0.0 1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3186 PF11382.3 EAQ86743.1 - 0.044 12.9 0.1 0.048 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Inhibitor_I9 PF05922.11 EAQ86743.1 - 0.044 14.3 0.1 0.078 13.5 0.0 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 HOOK PF05622.7 EAQ86744.1 - 1.7e-16 59.2 35.2 1.7e-16 59.2 24.4 2.6 2 1 0 2 2 2 1 HOOK protein DUF904 PF06005.7 EAQ86744.1 - 0.0012 19.0 4.4 0.0012 19.0 3.0 8.3 5 3 2 7 7 7 2 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EAQ86744.1 - 0.035 14.0 0.8 0.035 14.0 0.5 9.0 7 3 3 10 10 10 0 bZIP transcription factor KR PF08659.5 EAQ86744.1 - 5.7 6.5 8.1 5.9 6.5 0.4 3.4 3 0 0 3 3 3 0 KR domain ADK PF00406.17 EAQ86745.1 - 1.7e-59 200.0 0.0 2.1e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EAQ86745.1 - 6.6e-15 54.4 0.0 2.1e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EAQ86745.1 - 3.9e-07 30.9 0.1 6.5e-07 30.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ86745.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAQ86745.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EAQ86745.1 - 0.0052 17.0 0.1 0.021 15.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain Ribosom_S12_S23 PF00164.20 EAQ86747.1 - 6.9e-41 138.5 0.5 8.1e-41 138.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.22 EAQ86749.1 - 2.3e-66 219.5 6.4 4.4e-25 87.2 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EAQ86749.1 - 1.8e-11 44.0 0.3 8.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EAQ86749.1 - 5e-10 37.9 0.5 7e-05 21.8 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EAQ86749.1 - 2.7e-08 33.0 0.6 0.0017 18.0 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EAQ86749.1 - 6.1e-07 28.4 1.3 5.7e-05 22.2 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EAQ86749.1 - 5e-06 26.0 0.3 0.005 16.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAQ86749.1 - 0.04 13.9 0.0 0.61 10.1 0.0 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Cyclin_N PF00134.18 EAQ86750.1 - 2.6e-10 39.9 0.6 2.1e-09 37.0 0.2 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EAQ86750.1 - 0.0058 16.4 0.1 0.018 14.8 0.1 1.9 1 0 0 1 1 1 1 Transcription factor TFIIB repeat AP2 PF00847.15 EAQ86750.1 - 0.096 12.8 0.0 0.096 12.8 0.0 2.5 2 0 0 2 2 2 0 AP2 domain PAT1 PF09770.4 EAQ86751.1 - 5.8 5.0 17.3 7.7 4.6 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTB PF00651.26 EAQ86752.1 - 0.00042 20.2 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DUF4452 PF14618.1 EAQ86753.1 - 5.7e-77 257.1 11.9 7e-77 256.8 8.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) OGFr_III PF04680.8 EAQ86754.1 - 8.7 6.6 9.8 3 8.1 2.9 2.6 2 0 0 2 2 2 0 Opioid growth factor receptor repeat Barttin PF15462.1 EAQ86755.1 - 0.033 13.8 1.1 0.037 13.6 0.7 1.0 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF4228 PF14009.1 EAQ86755.1 - 0.04 14.0 0.1 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) JmjC PF02373.17 EAQ86756.1 - 1.9e-10 40.9 0.1 5.2e-10 39.5 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EAQ86756.1 - 3.2e-07 30.4 8.2 3.2e-07 30.4 5.7 3.1 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EAQ86756.1 - 0.044 13.2 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Condensation PF00668.15 EAQ86756.1 - 0.13 11.0 0.0 0.32 9.7 0.0 1.6 1 0 0 1 1 1 0 Condensation domain UbiA PF01040.13 EAQ86757.1 - 9.9e-33 113.4 22.6 1.3e-32 113.0 15.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RVT_1 PF00078.22 EAQ86760.1 - 2.4e-30 105.4 0.0 2.1e-28 99.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ86760.1 - 2e-14 53.2 0.0 1.1e-13 50.7 0.0 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ86760.1 - 1.1e-09 38.5 0.1 2.6e-09 37.4 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Radial_spoke_3 PF06098.6 EAQ86761.1 - 0.0017 17.4 3.9 0.002 17.2 2.7 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 AATF-Che1 PF13339.1 EAQ86761.1 - 0.0033 17.5 2.4 0.0046 17.0 1.6 1.2 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor AAA_32 PF13654.1 EAQ86761.1 - 0.013 14.2 0.8 0.015 14.0 0.6 1.1 1 0 0 1 1 1 0 AAA domain GrpE PF01025.14 EAQ86761.1 - 0.031 13.8 6.9 0.038 13.5 4.8 1.1 1 0 0 1 1 1 0 GrpE DUF904 PF06005.7 EAQ86761.1 - 0.031 14.5 5.9 0.046 14.0 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EAQ86761.1 - 0.04 13.5 4.9 0.046 13.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Toxin_YhaV PF11663.3 EAQ86761.1 - 0.053 13.2 1.0 0.21 11.3 0.2 1.8 1 1 1 2 2 2 0 Toxin with endonuclease activity YhaV CENP-Q PF13094.1 EAQ86761.1 - 0.055 13.4 6.1 0.066 13.2 4.2 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 EAQ86761.1 - 0.059 11.8 4.7 0.068 11.6 3.3 1.0 1 0 0 1 1 1 0 AAA domain Lge1 PF11488.3 EAQ86761.1 - 0.079 13.1 2.4 0.098 12.8 1.7 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Peptidase_S49_N PF08496.5 EAQ86761.1 - 0.11 12.3 3.9 0.13 12.0 2.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal IncA PF04156.9 EAQ86761.1 - 0.13 11.8 5.4 0.15 11.6 3.7 1.1 1 0 0 1 1 1 0 IncA protein PP_M1 PF03012.9 EAQ86761.1 - 0.13 11.6 1.7 0.15 11.3 1.2 1.0 1 0 0 1 1 1 0 Phosphoprotein Mnd1 PF03962.10 EAQ86761.1 - 0.13 11.9 6.8 0.17 11.5 4.7 1.1 1 0 0 1 1 1 0 Mnd1 family HopW1-1 PF15457.1 EAQ86761.1 - 0.13 11.2 0.3 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA DUF964 PF06133.6 EAQ86761.1 - 0.14 12.1 4.7 0.18 11.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF812 PF05667.6 EAQ86761.1 - 0.15 10.5 4.8 0.18 10.3 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc24 PF08286.6 EAQ86761.1 - 0.16 11.7 4.0 0.21 11.2 2.8 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ArgK PF03308.11 EAQ86761.1 - 0.17 10.6 0.7 0.31 9.7 0.6 1.5 2 0 0 2 2 2 0 ArgK protein DUF4407 PF14362.1 EAQ86761.1 - 0.19 10.6 3.6 0.22 10.4 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AKNA PF12443.3 EAQ86761.1 - 0.19 11.7 3.5 0.83 9.6 1.5 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF2828 PF11443.3 EAQ86761.1 - 0.21 9.7 1.4 0.23 9.6 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ax_dynein_light PF10211.4 EAQ86761.1 - 0.21 11.4 6.9 0.25 11.1 4.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain AIF-MLS PF14962.1 EAQ86761.1 - 0.25 10.9 3.8 0.29 10.7 2.6 1.0 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF972 PF06156.8 EAQ86761.1 - 0.26 11.6 4.3 0.32 11.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ATP-synt_B PF00430.13 EAQ86761.1 - 0.28 11.0 5.9 0.34 10.7 4.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RRN3 PF05327.6 EAQ86761.1 - 0.29 9.1 1.5 0.32 9.0 1.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TMF_DNA_bd PF12329.3 EAQ86761.1 - 0.29 10.9 9.8 0.45 10.3 6.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EAQ86761.1 - 0.45 9.5 6.1 0.51 9.3 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF106 PF01956.11 EAQ86761.1 - 0.6 9.6 2.1 0.66 9.4 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 HAUS6_N PF14661.1 EAQ86761.1 - 0.89 8.8 4.9 1 8.6 3.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-H PF05837.7 EAQ86761.1 - 0.91 9.7 5.6 1.1 9.4 3.9 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spore_coat_CotO PF14153.1 EAQ86761.1 - 0.92 8.9 7.1 1.1 8.6 5.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF607 PF04678.8 EAQ86761.1 - 0.93 9.3 4.7 1.4 8.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Atg14 PF10186.4 EAQ86761.1 - 1.8 7.4 7.1 2.2 7.1 4.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EAQ86761.1 - 2.5 8.0 14.8 17 5.3 10.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Atrophin-1 PF03154.10 EAQ86761.1 - 4.2 5.3 9.5 4.6 5.2 6.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Vfa1 PF08432.5 EAQ86761.1 - 7.3 6.5 12.1 11 5.9 6.3 1.8 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 APH PF01636.18 EAQ86762.1 - 0.0041 16.8 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAQ86762.1 - 0.0096 15.0 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAQ86762.1 - 0.0099 14.9 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EAQ86762.1 - 0.014 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3337 PF11816.3 EAQ86764.1 - 7.8e-100 334.4 0.1 8.3e-99 331.1 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EAQ86764.1 - 3.3e-22 77.4 8.9 1.7e-08 33.9 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAQ86764.1 - 0.0083 14.9 0.1 3.3 6.3 0.0 2.6 2 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EAQ86764.1 - 0.011 13.9 1.6 0.053 11.6 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Mito_carr PF00153.22 EAQ86765.1 - 2.4e-29 100.8 2.9 2.2e-14 52.9 0.9 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein ATP_bind_3 PF01171.15 EAQ86766.1 - 1.5e-30 106.0 0.0 3.4e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 EAQ86766.1 - 9e-05 22.0 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EAQ86766.1 - 0.03 13.2 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase SNARE PF05739.14 EAQ86767.1 - 6e-09 35.4 4.1 1.3e-08 34.3 2.8 1.6 1 0 0 1 1 1 1 SNARE domain Mito_fiss_reg PF05308.6 EAQ86767.1 - 0.043 13.1 2.7 0.078 12.3 1.8 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Sec23_helical PF04815.10 EAQ86767.1 - 0.094 12.1 0.1 0.7 9.3 0.0 2.4 2 1 1 3 3 3 0 Sec23/Sec24 helical domain CorA PF01544.13 EAQ86767.1 - 0.24 10.3 0.0 0.24 10.3 0.0 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF3716 PF12511.3 EAQ86768.1 - 4.3e-17 61.4 3.1 7.2e-17 60.7 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Herpes_UL17 PF04559.7 EAQ86769.1 - 0.012 14.2 0.2 0.014 14.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein Ank_2 PF12796.2 EAQ86771.1 - 9.3e-44 147.6 8.0 1.1e-17 64.1 0.1 5.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86771.1 - 3.9e-43 143.1 5.8 5.9e-07 28.9 0.0 10.1 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.1 EAQ86771.1 - 2.3e-28 95.3 1.0 0.0003 20.7 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EAQ86771.1 - 2.7e-28 97.7 0.7 1.2e-07 32.0 0.0 6.2 4 3 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ86771.1 - 2.4e-24 84.7 8.6 4.4e-06 26.7 0.1 6.7 5 2 2 7 7 7 5 Ankyrin repeats (many copies) DDE_1 PF03184.14 EAQ86772.1 - 3.1e-37 127.8 0.1 6.6e-37 126.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ86772.1 - 1.1e-10 41.1 0.0 3.5e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ86772.1 - 3.2e-09 36.1 0.0 6.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ86772.1 - 4.8e-06 26.3 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF948 PF06103.6 EAQ86772.1 - 0.25 11.2 2.6 0.54 10.1 1.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YlqD PF11068.3 EAQ86772.1 - 0.36 10.8 7.9 0.82 9.7 5.5 1.5 1 0 0 1 1 1 0 YlqD protein AAA_13 PF13166.1 EAQ86772.1 - 0.42 9.0 7.5 0.75 8.1 5.2 1.3 1 0 0 1 1 1 0 AAA domain APH PF01636.18 EAQ86773.1 - 5.9e-19 68.7 0.1 2.7e-18 66.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kelch_6 PF13964.1 EAQ86773.1 - 1.2e-12 47.4 6.1 1.4e-07 31.3 0.0 4.4 3 1 2 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EAQ86773.1 - 1.4e-09 37.3 8.3 2.9e-05 23.4 0.1 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EAQ86773.1 - 1.7e-09 37.3 3.0 0.0016 18.3 0.1 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 EAQ86773.1 - 9.9e-09 34.8 10.2 0.0038 16.9 0.4 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EAQ86773.1 - 4.1e-07 29.5 5.5 0.011 15.5 0.4 4.3 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EAQ86773.1 - 1.5e-06 28.1 19.0 0.00039 20.5 0.4 7.0 7 1 0 7 7 7 2 Galactose oxidase, central domain Choline_kinase PF01633.15 EAQ86773.1 - 0.0072 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RNA_polI_A14 PF08203.6 EAQ86773.1 - 0.026 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Fructosamin_kin PF03881.9 EAQ86773.1 - 0.081 11.8 0.0 0.67 8.8 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase PhoD PF09423.5 EAQ86774.1 - 3.3e-141 470.9 0.1 3.8e-123 411.4 0.1 2.1 1 1 1 2 2 2 2 PhoD-like phosphatase p450 PF00067.17 EAQ86774.1 - 1.5e-08 33.6 0.0 3.4e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 RRM_1 PF00076.17 EAQ86776.1 - 1e-19 69.8 0.0 1.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ86776.1 - 3.8e-14 52.4 0.0 4.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ86776.1 - 7.9e-07 28.8 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2263 PF10021.4 EAQ86776.1 - 1.6 8.6 3.8 2.2 8.2 2.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) Hydrophobin PF01185.13 EAQ86779.1 - 0.019 15.3 12.9 0.049 14.0 3.7 2.0 1 1 1 2 2 2 0 Fungal hydrophobin Toxin_12 PF07740.7 EAQ86779.1 - 5.9 7.4 8.4 17 5.9 0.4 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin APH PF01636.18 EAQ86780.1 - 1.6e-20 73.8 0.1 6.1e-20 71.9 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 EAQ86781.1 - 1.2e-33 116.3 82.8 1.3e-24 86.5 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ86781.1 - 0.00022 20.9 3.1 0.25 11.1 0.0 3.9 3 1 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 EAQ86781.1 - 0.047 12.0 37.7 0.11 10.9 15.9 3.2 1 1 2 3 3 3 0 MFS/sugar transport protein MS_channel PF00924.13 EAQ86781.1 - 0.21 10.8 6.1 0.39 10.0 4.2 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel Fungal_trans PF04082.13 EAQ86782.1 - 6.9e-15 54.6 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ86782.1 - 1.3e-08 34.5 11.9 3.3e-08 33.3 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EAQ86782.1 - 1.2e-05 25.1 1.4 2e-05 24.4 0.3 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Dickkopf_N PF04706.7 EAQ86782.1 - 2 8.6 11.5 4.5 7.5 8.0 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Glyco_hydro_61 PF03443.9 EAQ86783.1 - 2.1e-37 129.0 0.2 2.5e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CoA_transf_3 PF02515.12 EAQ86784.1 - 0.047 12.9 0.7 0.089 12.0 0.1 1.7 2 0 0 2 2 2 0 CoA-transferase family III NUDIX PF00293.23 EAQ86785.1 - 9.8e-05 22.0 0.2 0.00052 19.6 0.1 2.1 2 1 0 2 2 2 1 NUDIX domain F-box-like PF12937.2 EAQ86788.1 - 5e-07 29.3 0.2 1.2e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ86788.1 - 0.00079 19.0 4.5 0.0066 16.0 3.1 2.4 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EAQ86788.1 - 0.006 16.2 0.3 0.02 14.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like domain Ta0938 PF11494.3 EAQ86788.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Ta0938 Peptidase_M41 PF01434.13 EAQ86790.1 - 5.1e-63 212.3 0.2 8.4e-63 211.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EAQ86790.1 - 6.2e-43 146.1 0.0 1.6e-42 144.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ86790.1 - 5.6e-06 26.1 0.0 1.7e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ86790.1 - 2.6e-05 24.3 1.6 0.0011 18.9 0.0 3.1 3 1 1 4 4 3 1 AAA ATPase domain TIP49 PF06068.8 EAQ86790.1 - 3.8e-05 22.5 0.0 6.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EAQ86790.1 - 4.4e-05 24.2 0.0 0.00011 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ86790.1 - 0.00014 21.3 0.3 0.037 13.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ86790.1 - 0.00024 21.2 0.1 0.0086 16.2 0.1 2.8 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EAQ86790.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ86790.1 - 0.0013 18.4 0.3 0.0043 16.7 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EAQ86790.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAQ86790.1 - 0.0019 17.6 0.1 0.0055 16.1 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAQ86790.1 - 0.0057 15.7 0.6 0.019 14.0 0.3 2.0 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EAQ86790.1 - 0.007 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAQ86790.1 - 0.017 14.2 0.2 0.036 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EAQ86790.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAQ86790.1 - 0.026 13.6 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.9 EAQ86790.1 - 0.031 14.2 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EAQ86790.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EAQ86790.1 - 0.062 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EAQ86790.1 - 0.12 11.6 0.7 0.27 10.4 0.2 1.7 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 EAQ86790.1 - 0.14 11.8 0.5 1.1 8.9 0.1 2.4 3 0 0 3 3 2 0 NACHT domain Steroid_dh PF02544.11 EAQ86791.1 - 1.8e-20 73.2 1.4 2e-19 69.8 1.0 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EAQ86791.1 - 0.0025 17.1 0.9 0.0039 16.5 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF544 PF04424.8 EAQ86792.1 - 2.3e-13 49.9 0.0 3.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF1977 PF09320.6 EAQ86793.1 - 2.6e-24 85.5 0.0 6e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EAQ86793.1 - 5.7e-22 77.2 0.2 1.1e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF481 PF04338.7 EAQ86793.1 - 0.19 11.4 0.7 0.83 9.3 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF481 DUF2416 PF10315.4 EAQ86794.1 - 9.2e-05 22.6 0.2 0.00024 21.2 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Y_phosphatase2 PF03162.8 EAQ86795.1 - 3.9e-45 153.1 0.0 5.5e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EAQ86795.1 - 3.3e-09 37.2 0.0 1.1e-08 35.4 0.0 1.8 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EAQ86795.1 - 0.0018 17.8 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAQ86795.1 - 0.0044 16.3 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase adh_short PF00106.20 EAQ86796.1 - 1.9e-29 102.7 2.0 3e-29 102.0 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ86796.1 - 1.5e-26 93.6 0.5 1.7e-26 93.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ86796.1 - 3.2e-11 43.2 2.4 1.3e-10 41.2 1.6 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ86796.1 - 3.9e-06 26.4 0.2 6.7e-06 25.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Herpes_gE PF02480.11 EAQ86797.1 - 0.1 10.8 0.2 0.19 9.9 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PepSY_TM_2 PF13703.1 EAQ86797.1 - 0.12 12.5 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix EphA2_TM PF14575.1 EAQ86797.1 - 0.19 12.1 0.5 0.35 11.2 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EAQ86797.1 - 0.25 10.8 2.4 0.47 10.0 1.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 EAQ86797.1 - 0.52 10.0 0.5 0.94 9.1 0.4 1.3 1 0 0 1 1 1 0 TMEM154 protein family RabGAP-TBC PF00566.13 EAQ86798.1 - 2.5e-47 161.1 0.0 4.1e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.2 EAQ86799.1 - 1.2e-05 24.8 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Suf PF05843.9 EAQ86800.1 - 0.36 10.5 3.4 0.45 10.2 2.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rrn6 PF10214.4 EAQ86800.1 - 2.4 6.1 10.7 3.2 5.7 7.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Septin PF00735.13 EAQ86801.1 - 8.9e-113 375.9 0.9 1.1e-112 375.7 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EAQ86801.1 - 1.5e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAQ86801.1 - 1.8e-06 27.2 0.0 3.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAQ86801.1 - 2.1e-05 23.7 0.0 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAQ86801.1 - 6.7e-05 22.4 0.3 0.0055 16.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAQ86801.1 - 0.00092 19.0 0.5 1.1 9.0 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EAQ86801.1 - 0.0028 17.1 0.1 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EAQ86801.1 - 0.0037 17.6 0.0 0.0055 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ86801.1 - 0.0065 16.6 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EAQ86801.1 - 0.0095 15.0 0.1 0.06 12.4 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EAQ86801.1 - 0.013 15.7 0.9 0.02 15.1 0.6 1.7 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 EAQ86801.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EAQ86801.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAQ86801.1 - 0.036 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EAQ86801.1 - 0.049 12.5 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.17 EAQ86801.1 - 0.065 12.6 0.1 0.23 10.8 0.0 1.9 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.1 EAQ86801.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 EAQ86802.1 - 8.4e-21 73.0 12.2 1.7e-08 33.9 0.1 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EAQ86802.1 - 0.00017 21.1 0.7 0.0035 16.8 0.1 2.1 1 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 EAQ86802.1 - 0.00052 20.2 2.4 0.23 11.8 0.1 3.0 3 0 0 3 3 3 2 PQQ-like domain eIF2A PF08662.6 EAQ86802.1 - 0.001 18.8 0.0 0.11 12.1 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EAQ86802.1 - 0.0015 17.8 0.1 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EAQ86802.1 - 0.0028 16.4 0.0 0.045 12.5 0.0 2.6 2 2 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EAQ86802.1 - 0.0053 14.9 0.3 0.13 10.3 0.3 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EAQ86802.1 - 0.029 13.4 0.1 8.6 5.3 0.0 3.3 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DNA_pol_delta_4 PF04081.8 EAQ86803.1 - 1.1e-30 106.5 0.6 2.3e-30 105.4 0.4 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF3597 PF12200.3 EAQ86803.1 - 1.6 9.1 5.2 1.7 9.0 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) DUF2419 PF10343.4 EAQ86804.1 - 1.1e-123 412.1 0.0 1.3e-123 411.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 EAQ86805.1 - 1.5e-41 141.3 0.2 2.6e-41 140.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EAQ86805.1 - 6.5e-24 83.2 2.0 7.7e-24 83.0 0.2 2.0 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAQ86805.1 - 1.1e-19 69.5 0.6 2.1e-19 68.6 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EAQ86805.1 - 1.2e-12 47.7 0.0 3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EAQ86805.1 - 0.00021 21.5 0.2 0.00092 19.4 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EAQ86805.1 - 0.005 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EAQ86805.1 - 0.021 15.2 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EAQ86806.1 - 6.2e-24 84.7 0.6 8.5e-24 84.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ86806.1 - 1.2e-09 38.2 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ86806.1 - 3.3e-08 33.2 0.0 4.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EAQ86806.1 - 5.6e-08 32.6 0.6 9e-08 31.9 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAQ86806.1 - 7.6e-05 22.7 0.3 0.00024 21.1 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EAQ86806.1 - 9.5e-05 21.4 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EAQ86806.1 - 0.00017 20.7 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EAQ86806.1 - 0.0015 18.6 0.1 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EAQ86806.1 - 0.0028 16.6 0.0 0.0046 15.8 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EAQ86806.1 - 0.0035 17.7 0.4 0.0083 16.5 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EAQ86806.1 - 0.0055 16.3 0.2 0.0088 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EAQ86806.1 - 0.0062 16.2 2.0 0.009 15.7 0.8 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 EAQ86806.1 - 0.031 13.8 0.1 0.051 13.1 0.1 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 EAQ86806.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 EAQ86806.1 - 0.038 13.4 0.1 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EAQ86806.1 - 0.074 12.1 1.3 0.1 11.7 0.1 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAP2 PF01569.16 EAQ86807.1 - 1.9e-14 53.4 3.2 4.4e-14 52.2 2.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily JmjC PF02373.17 EAQ86808.1 - 1.6e-36 124.9 0.4 4.9e-36 123.4 0.3 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EAQ86808.1 - 1.6e-21 76.3 3.9 3e-21 75.4 2.7 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAQ86808.1 - 4.3e-21 74.8 4.4 4.3e-21 74.8 3.1 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 EAQ86808.1 - 2.5e-13 49.2 1.4 5e-13 48.3 1.0 1.5 1 0 0 1 1 1 1 jmjN domain DUF4440 PF14534.1 EAQ86809.1 - 0.0003 20.9 0.0 0.00041 20.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3995 PF13160.1 EAQ86810.1 - 1.7 8.6 5.0 1.7 8.6 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) AA_permease PF00324.16 EAQ86811.1 - 3.6e-99 332.2 32.9 4.4e-49 167.1 0.9 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAQ86811.1 - 1.5e-21 76.4 34.1 1.8e-08 33.3 3.6 3.2 2 2 1 3 3 3 3 Amino acid permease RVT_1 PF00078.22 EAQ86812.1 - 1.2e-12 47.6 0.0 2.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ86812.1 - 2.8e-11 43.5 0.0 6.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 EAQ86812.1 - 0.052 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease CAF-1_p150 PF11600.3 EAQ86812.1 - 2.1 7.6 23.7 3.8 6.8 16.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 EAQ86812.1 - 6 5.2 22.7 9.3 4.5 15.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-C2H2 PF00096.21 EAQ86812.1 - 8.2 6.9 16.1 1.2 9.5 4.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Clr5 PF14420.1 EAQ86815.1 - 2.1e-07 30.7 0.0 6e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Clr5 domain adh_short PF00106.20 EAQ86818.1 - 9.6e-08 32.1 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EAQ86818.1 - 1.1e-07 31.5 0.0 1.2e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ86818.1 - 1.2e-07 31.8 0.1 1.8e-07 31.3 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ86818.1 - 8.3e-07 27.9 0.0 1e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAQ86818.1 - 1.6e-06 27.2 0.0 1.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.12 EAQ86818.1 - 1e-05 25.8 0.1 1.6e-05 25.2 0.1 1.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EAQ86818.1 - 1.5e-05 24.0 0.0 1.7e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EAQ86818.1 - 3.6e-05 23.5 0.0 4.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EAQ86818.1 - 0.0038 16.2 0.0 0.0043 16.1 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EAQ86818.1 - 0.0042 16.3 0.1 0.0044 16.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EAQ86818.1 - 0.016 14.1 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain CoA_binding_2 PF13380.1 EAQ86818.1 - 0.08 13.1 0.0 0.097 12.8 0.0 1.1 1 0 0 1 1 1 0 CoA binding domain Ufd2P_core PF10408.4 EAQ86819.1 - 5e-204 679.1 5.7 5.9e-204 678.8 3.9 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EAQ86819.1 - 0.00035 20.4 0.4 0.0014 18.5 0.3 2.1 1 0 0 1 1 1 1 U-box domain CCDC-167 PF15188.1 EAQ86819.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-TRAF PF02176.13 EAQ86821.1 - 9.4e-11 41.9 32.2 9.7e-06 25.8 7.8 3.8 1 1 2 3 3 3 3 TRAF-type zinc finger zf-RING_2 PF13639.1 EAQ86821.1 - 5.5e-08 32.5 1.2 5.5e-08 32.5 0.8 3.5 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ86821.1 - 2.4e-07 30.6 1.5 2.4e-07 30.6 1.0 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ86821.1 - 6.5e-07 28.9 0.6 6.5e-07 28.9 0.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ86821.1 - 2e-06 27.3 1.4 2e-06 27.3 1.0 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAQ86821.1 - 2e-05 24.1 1.3 2e-05 24.1 0.9 4.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ86821.1 - 3.7e-05 23.5 1.6 3.7e-05 23.5 1.1 3.0 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAQ86821.1 - 0.00016 21.2 0.5 0.00086 18.9 0.4 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EAQ86821.1 - 0.00022 21.2 0.2 0.00022 21.2 0.2 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EAQ86821.1 - 0.044 13.3 0.8 0.044 13.3 0.5 3.8 3 2 0 3 3 3 0 RING/Ubox like zinc-binding domain SPO22 PF08631.5 EAQ86822.1 - 4.5e-79 265.4 0.0 4.5e-79 265.4 0.0 2.0 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EAQ86822.1 - 7e-08 32.2 4.2 0.0014 18.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat PAS PF00989.19 EAQ86822.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF823 PF05689.6 EAQ86822.1 - 0.044 13.1 0.3 0.11 11.8 0.2 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) TPR_2 PF07719.12 EAQ86822.1 - 0.048 13.5 0.2 5.5 7.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ86822.1 - 0.081 12.5 0.3 8.8 6.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ald_Xan_dh_C2 PF02738.13 EAQ86823.1 - 3.8e-191 636.1 0.0 5.1e-191 635.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EAQ86823.1 - 1e-48 164.9 0.0 1.9e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EAQ86823.1 - 4.9e-32 109.9 0.8 4.2e-31 106.9 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EAQ86823.1 - 8.5e-31 106.3 0.0 1.8e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EAQ86823.1 - 5.4e-29 99.9 0.1 1.1e-28 98.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EAQ86823.1 - 3.3e-08 33.1 0.1 3.3e-08 33.1 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 EAQ86823.1 - 0.019 14.4 0.1 0.053 13.0 0.1 1.7 2 0 0 2 2 2 0 DUF218 domain Aldedh PF00171.17 EAQ86824.1 - 1.9e-140 468.2 0.0 2.3e-140 468.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EAQ86824.1 - 2.5e-06 26.4 0.8 0.0055 15.4 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Thiolase_C PF02803.13 EAQ86826.1 - 1.3e-08 34.2 1.5 2.9e-08 33.1 0.2 2.2 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EAQ86826.1 - 2.3e-07 30.3 0.8 1.8e-05 24.3 0.1 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EAQ86826.1 - 9.1e-06 24.8 1.5 3.4e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EAQ86826.1 - 0.0039 16.7 0.1 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain CHAP PF05257.11 EAQ86826.1 - 0.018 14.7 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 CHAP domain SpoVAD PF07451.6 EAQ86826.1 - 0.039 12.3 0.8 0.073 11.5 0.1 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) S4 PF01479.20 EAQ86826.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain PMP22_Claudin PF00822.15 EAQ86827.1 - 0.00069 19.3 1.9 0.0032 17.1 0.1 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Cyto_ox_2 PF02322.10 EAQ86827.1 - 0.0012 18.0 0.8 0.0015 17.7 0.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase subunit II GPDPase_memb PF10110.4 EAQ86827.1 - 0.01 15.2 0.3 0.017 14.5 0.2 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF2231 PF09990.4 EAQ86827.1 - 0.63 10.4 4.6 0.31 11.3 1.6 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) COX4_pro PF03626.9 EAQ86827.1 - 2.8 8.0 8.2 13 5.9 5.7 2.2 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV PPR_2 PF13041.1 EAQ86828.1 - 3.1e-20 71.8 0.1 1.8e-08 34.2 0.0 4.9 3 2 1 4 4 4 4 PPR repeat family PPR PF01535.15 EAQ86828.1 - 3.1e-15 54.9 10.0 9.9e-06 25.2 0.0 6.4 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.1 EAQ86828.1 - 6.3e-14 51.0 5.1 0.0059 16.7 0.0 6.7 6 0 0 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EAQ86828.1 - 1.4e-10 40.4 8.9 0.0003 20.1 0.1 5.6 5 1 0 5 5 5 3 PPR repeat MRP-S25 PF13741.1 EAQ86829.1 - 1.1e-66 224.5 7.4 2.1e-65 220.4 5.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 Alg14 PF08660.6 EAQ86830.1 - 3e-38 131.4 0.0 4.7e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Sec6 PF06046.8 EAQ86831.1 - 5.9e-147 490.1 11.7 1.4e-145 485.5 8.1 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EAQ86831.1 - 0.0013 17.6 1.2 0.0013 17.6 0.8 1.9 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 EAQ86831.1 - 0.082 11.7 4.9 0.096 11.5 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DASH_Dam1 PF08653.5 EAQ86831.1 - 1 9.1 4.1 8.2 6.2 0.1 4.1 4 1 1 5 5 5 0 DASH complex subunit Dam1 COX7C PF02935.11 EAQ86832.1 - 9.9e-14 50.8 1.0 1.5e-13 50.2 0.7 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Deltaretro_Tax PF05599.6 EAQ86832.1 - 0.11 12.8 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Pyr_redox_2 PF07992.9 EAQ86833.1 - 1.8e-38 132.4 0.0 3.6e-38 131.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ86833.1 - 6.6e-18 64.8 7.5 1.3e-16 60.7 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EAQ86833.1 - 3.4e-17 62.4 0.0 1.3e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 EAQ86833.1 - 1.3e-09 38.4 0.1 1e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ86833.1 - 5.8e-05 21.7 8.0 0.13 10.7 0.0 3.1 2 1 1 3 3 3 3 HI0933-like protein K_oxygenase PF13434.1 EAQ86833.1 - 0.00024 20.1 0.2 0.0045 15.9 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EAQ86833.1 - 0.0021 16.9 1.2 0.12 11.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EAQ86833.1 - 0.0026 16.8 0.1 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EAQ86833.1 - 0.0089 15.6 1.6 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EAQ86833.1 - 0.021 13.9 0.7 0.045 12.8 0.5 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EAQ86833.1 - 0.037 12.8 6.0 1.7 7.3 1.7 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EAQ86833.1 - 0.071 11.9 6.7 0.14 11.0 3.1 2.5 3 1 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EAQ86833.1 - 0.1 12.6 1.0 0.26 11.3 0.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EAQ86833.1 - 6.6 6.3 6.6 0.46 10.1 0.1 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ydc2-catalyt PF09159.5 EAQ86834.1 - 1.7e-62 211.3 0.0 2.2e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 EAQ86834.1 - 0.00046 19.6 0.6 0.0012 18.2 0.4 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 EAQ86834.1 - 0.029 14.2 0.0 10 5.9 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A22 protein DUF3530 PF12048.3 EAQ86834.1 - 0.2 10.6 4.6 0.28 10.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Helicase_C PF00271.26 EAQ86835.1 - 1.7e-17 63.0 0.0 6.3e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ86835.1 - 1.8e-17 63.3 0.0 4.9e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EAQ86835.1 - 0.016 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain SOG2 PF10428.4 EAQ86836.1 - 1.7e-115 386.1 3.0 1.7e-115 386.1 2.1 3.9 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.1 EAQ86836.1 - 7.7e-10 38.3 0.4 2.4e-09 36.8 0.3 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 EAQ86836.1 - 1.4e-08 34.1 5.0 2e-05 24.0 0.7 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) GCN5L1 PF06320.8 EAQ86836.1 - 1.8e-06 27.7 0.2 4.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) LRR_1 PF00560.28 EAQ86836.1 - 0.0027 17.4 0.3 0.6 10.3 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat DUF2408 PF10303.4 EAQ86836.1 - 0.059 13.4 0.5 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Steroid_dh PF02544.11 EAQ86837.1 - 2.8e-21 75.8 0.2 5.6e-21 74.8 0.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EAQ86837.1 - 6.4e-05 23.0 0.3 0.00032 20.7 0.2 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EAQ86837.1 - 0.0014 17.9 0.2 0.002 17.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TPR_10 PF13374.1 EAQ86838.1 - 2.7e-54 179.6 16.1 1.4e-11 43.9 0.1 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ86838.1 - 1.8e-46 155.9 12.4 1.6e-14 53.5 0.5 4.7 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ86838.1 - 3.3e-19 67.1 13.8 0.00077 19.0 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ86838.1 - 5.3e-16 57.1 9.5 0.00067 19.3 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ86838.1 - 3.6e-15 54.8 3.7 0.0076 15.8 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ86838.1 - 2.3e-13 49.5 1.9 1.1e-06 28.1 0.1 3.9 2 2 3 5 5 5 5 TPR repeat TPR_16 PF13432.1 EAQ86838.1 - 3.7e-13 49.7 5.9 0.0028 18.2 0.2 6.0 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ86838.1 - 1.1e-12 47.1 0.5 0.48 11.0 0.0 6.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ86838.1 - 2.1e-10 39.9 0.0 0.53 10.6 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86838.1 - 4.1e-08 33.4 5.3 0.029 14.7 0.1 4.7 3 1 2 5 5 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 EAQ86838.1 - 8.7e-06 25.9 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.1 EAQ86838.1 - 4.9e-05 23.5 12.1 2.3 8.8 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ86838.1 - 9.9e-05 21.8 5.8 1.7 8.5 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ86838.1 - 0.00018 21.8 17.6 0.49 11.1 0.1 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_3 PF07720.7 EAQ86838.1 - 0.005 16.6 0.6 7.3 6.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Sigma70_ner PF04546.8 EAQ86838.1 - 0.034 13.7 1.7 0.057 13.0 1.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1858 PF08984.6 EAQ86838.1 - 0.065 12.9 0.0 26 4.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1858) PNP_UDP_1 PF01048.15 EAQ86839.1 - 0.00046 19.2 0.0 0.00097 18.1 0.0 1.6 2 0 0 2 2 2 1 Phosphorylase superfamily rRNA_proc-arch PF13234.1 EAQ86840.1 - 1.1e-32 113.2 0.0 2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.24 EAQ86840.1 - 1.9e-21 76.3 0.0 3.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ86840.1 - 1.9e-08 34.0 0.0 3.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ86840.1 - 0.0015 18.4 0.0 0.024 14.4 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EAQ86840.1 - 0.05 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EAQ86840.1 - 0.095 12.3 0.2 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Ras PF00071.17 EAQ86841.1 - 2.6e-15 56.1 0.0 3.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EAQ86841.1 - 3.2e-06 26.4 0.0 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAQ86841.1 - 3.4e-06 27.0 0.0 9.2e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ86841.1 - 1.9e-05 25.1 0.0 2.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EAQ86841.1 - 0.0002 21.2 0.1 0.021 14.6 0.1 2.3 1 1 1 2 2 2 1 Dynamin family cobW PF02492.14 EAQ86841.1 - 0.0067 15.8 0.1 0.11 11.8 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EAQ86841.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Arf PF00025.16 EAQ86841.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 EAQ86841.1 - 0.023 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EAQ86841.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EAQ86841.1 - 0.033 13.3 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 EAQ86841.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GTP_EFTU PF00009.22 EAQ86841.1 - 0.047 13.1 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain IIGP PF05049.8 EAQ86841.1 - 0.057 12.2 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 EAQ86841.1 - 0.08 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.6 EAQ86841.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Septin PF00735.13 EAQ86841.1 - 0.27 10.2 0.0 0.51 9.3 0.0 1.4 1 0 0 1 1 1 0 Septin Aminotran_1_2 PF00155.16 EAQ86842.1 - 1.4e-64 218.3 0.0 1.6e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EAQ86842.1 - 2.8e-05 23.3 0.0 4.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EAQ86842.1 - 0.0001 21.5 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EAQ86842.1 - 0.001 17.4 0.0 0.0019 16.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EAQ86842.1 - 0.0047 15.7 0.0 0.011 14.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DUF3455 PF11937.3 EAQ86843.1 - 0.085 12.7 0.1 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) HMA PF00403.21 EAQ86845.1 - 8e-16 57.9 1.2 1.3e-15 57.2 0.8 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1280 PF06918.9 EAQ86845.1 - 0.052 12.7 0.2 0.06 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) Tcf25 PF04910.9 EAQ86846.1 - 5.9e-71 239.2 0.1 8.7e-71 238.7 0.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 NST1 PF13945.1 EAQ86846.1 - 0.038 14.0 5.3 0.067 13.2 3.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator FtsX PF02687.16 EAQ86847.1 - 2.3 7.9 13.2 0.95 9.2 0.3 3.2 3 0 0 3 3 3 0 FtsX-like permease family LSM14 PF12701.2 EAQ86848.1 - 1e-30 105.4 0.0 2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EAQ86848.1 - 8.5e-18 64.8 1.4 8.5e-18 64.8 1.0 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EAQ86848.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DENN PF02141.16 EAQ86849.1 - 2.8e-39 134.7 0.1 5.3e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EAQ86849.1 - 3.2e-05 23.8 0.0 9.6e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Dfp1_Him1_M PF08630.5 EAQ86849.1 - 0.013 15.3 1.4 0.16 11.7 1.0 2.3 2 0 0 2 2 2 0 Dfp1/Him1, central region TMF_TATA_bd PF12325.3 EAQ86849.1 - 0.68 9.6 13.1 3.5 7.3 1.7 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Elongin_A PF06881.6 EAQ86849.1 - 4.9 7.5 12.3 0.056 13.8 2.6 2.2 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2570 PF10828.3 EAQ86849.1 - 6.6 6.3 8.0 8 6.1 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DNA_binding_1 PF01035.15 EAQ86850.1 - 3.3e-10 39.5 0.0 6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain GRP PF07172.6 EAQ86851.1 - 0.35 11.3 18.4 0.071 13.6 9.7 2.2 2 0 0 2 2 2 0 Glycine rich protein family CENP-W PF15510.1 EAQ86852.1 - 0.00087 19.2 0.0 0.001 19.0 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component W CBFD_NFYB_HMF PF00808.18 EAQ86852.1 - 0.0034 17.3 1.0 0.44 10.6 0.1 2.3 1 1 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Prefoldin_2 PF01920.15 EAQ86853.1 - 1.4e-08 34.4 3.8 1.4e-08 34.4 2.6 1.3 2 0 0 2 2 2 1 Prefoldin subunit APG6 PF04111.7 EAQ86853.1 - 4.7 6.1 8.1 5 6.0 5.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 EAQ86853.1 - 8.6 6.6 8.7 9 6.5 6.0 1.0 1 0 0 1 1 1 0 AAA domain DASH_Dad1 PF08649.5 EAQ86854.1 - 2.2e-21 75.3 2.8 4.9e-17 61.3 1.1 2.1 2 0 0 2 2 2 2 DASH complex subunit Dad1 WVELL PF14043.1 EAQ86854.1 - 0.044 13.3 0.4 0.094 12.3 0.3 1.7 1 1 0 1 1 1 0 WVELL protein Ras PF00071.17 EAQ86855.1 - 3.8e-48 162.9 0.0 4.7e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ86855.1 - 5.2e-12 46.2 0.0 7.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ86855.1 - 1.3e-05 24.5 0.0 3.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Skp1_POZ PF03931.10 EAQ86856.1 - 4.3e-13 49.1 0.0 6.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.8 EAQ86857.1 - 8.3e-53 178.1 0.0 1.7e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EAQ86857.1 - 3.5e-09 36.3 1.1 6.8e-09 35.4 0.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Abhydrolase_6 PF12697.2 EAQ86858.1 - 3.5e-28 99.0 2.2 5.7e-28 98.3 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ86858.1 - 1.8e-17 63.4 0.0 3.5e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ86858.1 - 1.1e-10 41.5 0.1 1.6e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EAQ86858.1 - 1.1e-05 25.7 0.1 1.7e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EAQ86858.1 - 1.8e-05 24.4 0.1 3.4e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAQ86858.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EAQ86858.1 - 0.00021 20.5 0.1 0.00056 19.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EAQ86858.1 - 0.0018 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AXE1 PF05448.7 EAQ86858.1 - 0.0043 15.6 0.4 0.29 9.6 0.3 2.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF3089 PF11288.3 EAQ86858.1 - 0.0051 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Lipase_3 PF01764.20 EAQ86858.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EAQ86858.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3530 PF12048.3 EAQ86858.1 - 0.04 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Ycf1 PF05758.7 EAQ86864.1 - 0.053 11.2 6.2 0.063 10.9 4.3 1.0 1 0 0 1 1 1 0 Ycf1 Sec62 PF03839.11 EAQ86864.1 - 0.23 10.8 5.6 0.31 10.4 3.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2265 PF10023.4 EAQ86864.1 - 0.72 8.9 18.9 1 8.4 13.1 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) GAGA_bind PF06217.7 EAQ86864.1 - 0.85 9.5 11.9 1.2 8.9 8.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.7 EAQ86864.1 - 1.9 7.0 14.3 2.4 6.6 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FUSC PF04632.7 EAQ86864.1 - 2.6 6.3 4.8 4.7 5.5 3.4 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family UPF0560 PF10577.4 EAQ86864.1 - 6 4.9 21.2 8.9 4.4 14.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DDHD PF02862.12 EAQ86864.1 - 6.9 6.3 10.7 9.7 5.9 7.4 1.2 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 EAQ86864.1 - 6.9 6.3 10.1 10 5.7 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A EF-hand_6 PF13405.1 EAQ86865.1 - 2.5e-08 33.1 1.4 0.00083 19.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EAQ86865.1 - 1.3e-07 31.6 0.6 1.3e-07 31.6 0.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EAQ86865.1 - 1.7e-06 26.9 1.5 1.4e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EAQ86865.1 - 3.9e-06 25.9 3.2 4.3e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EAQ86865.1 - 0.0002 20.9 1.0 0.00066 19.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair DUF2470 PF10615.4 EAQ86866.1 - 9.2e-25 86.6 0.0 1.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Met_10 PF02475.11 EAQ86866.1 - 2.5e-05 23.9 0.0 0.00023 20.8 0.0 2.0 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EAQ86866.1 - 0.011 15.7 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EAQ86866.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 EAQ86866.1 - 0.067 11.8 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.2 EAQ86866.1 - 0.13 12.8 0.2 0.31 11.6 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ86866.1 - 0.25 10.9 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 EAQ86867.1 - 7.8e-15 54.4 1.3 1.3e-14 53.6 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ86867.1 - 1.1e-07 31.6 7.4 2.1e-07 30.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 EAQ86868.1 - 8.5e-15 54.8 0.2 5.2e-14 52.2 0.1 2.3 1 1 0 1 1 1 1 Phosphoesterase family Pirin_C PF05726.8 EAQ86869.1 - 9.8e-23 80.2 0.1 1.7e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.11 EAQ86869.1 - 4.2e-15 55.5 0.0 1.1e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Pirin DUF4075 PF13294.1 EAQ86869.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) Cupin_2 PF07883.6 EAQ86869.1 - 0.31 10.5 1.8 1.2 8.7 0.1 2.6 3 1 0 3 3 3 0 Cupin domain zf-HIT PF04438.11 EAQ86870.1 - 9.3e-11 41.1 9.5 1.3e-10 40.6 6.6 1.2 1 0 0 1 1 1 1 HIT zinc finger DUF605 PF04652.11 EAQ86870.1 - 1.3 8.3 12.5 2.1 7.6 8.6 1.2 1 0 0 1 1 1 0 Vta1 like ubiquitin PF00240.18 EAQ86872.1 - 0.00011 21.5 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family MIP-T3 PF10243.4 EAQ86872.1 - 2.1 6.7 27.1 2.9 6.2 18.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop PF01798.13 EAQ86873.1 - 2.4e-52 176.2 1.5 4.6e-52 175.3 1.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 EAQ86873.1 - 1.2e-20 73.4 0.7 1.2e-20 73.4 0.5 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain NOSIC PF08060.8 EAQ86873.1 - 1.2e-14 53.7 0.1 3.1e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain vATP-synt_AC39 PF01992.11 EAQ86874.1 - 2.9e-107 358.6 0.0 3.6e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DHHA1 PF02272.14 EAQ86874.1 - 0.065 12.9 4.3 0.056 13.1 1.4 2.1 2 0 0 2 2 2 0 DHHA1 domain SMC_Nse1 PF07574.8 EAQ86874.1 - 0.15 11.6 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Ribosomal_S15 PF00312.17 EAQ86875.1 - 1.2e-14 53.7 0.2 4.9e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 EAQ86876.1 - 2.1e-43 147.9 0.0 3.5e-23 81.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 RasGEF PF00617.14 EAQ86877.1 - 2.4e-49 167.6 0.1 3.5e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAQ86877.1 - 4.2e-14 52.5 0.2 8.6e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif F-box-like PF12937.2 EAQ86878.1 - 0.017 14.8 0.1 0.051 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.2 EAQ86879.1 - 5e-72 238.2 4.6 2.4e-22 79.0 0.1 4.7 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86879.1 - 1.9e-71 232.4 17.4 1e-07 31.3 0.1 10.5 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 EAQ86879.1 - 4.8e-48 160.7 4.4 1.8e-07 31.4 0.0 9.5 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ86879.1 - 4.4e-42 141.1 7.4 5.5e-07 29.6 0.1 9.1 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86879.1 - 6.2e-30 100.2 6.4 0.061 13.5 0.0 10.0 10 0 0 10 10 9 8 Ankyrin repeat PNP_UDP_1 PF01048.15 EAQ86879.1 - 8.1e-10 38.0 0.2 8.5e-09 34.7 0.1 2.8 3 1 0 3 3 3 1 Phosphorylase superfamily NACHT PF05729.7 EAQ86879.1 - 3.5e-09 36.5 0.5 7.4e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAQ86879.1 - 6.9e-06 26.1 0.5 6.9e-06 26.1 0.3 3.3 4 0 0 4 4 4 1 AAA ATPase domain DUF1843 PF08898.5 EAQ86879.1 - 0.00063 19.7 24.5 0.33 11.0 0.3 6.0 4 2 1 5 5 5 4 Domain of unknown function (DUF1843) NB-ARC PF00931.17 EAQ86879.1 - 0.001 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EAQ86879.1 - 0.0012 18.9 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ86879.1 - 0.0031 17.3 0.0 0.32 10.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ86879.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase UPF0184 PF03670.8 EAQ86879.1 - 0.042 14.0 0.1 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) KxDL PF10241.4 EAQ86883.1 - 1.2e-32 111.6 3.0 1.6e-32 111.2 2.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein Syntaxin PF00804.20 EAQ86883.1 - 0.19 11.8 1.7 0.3 11.2 0.1 1.8 1 1 1 2 2 2 0 Syntaxin Mating_C PF12737.2 EAQ86883.1 - 5.3 5.8 13.2 0.47 9.2 0.9 2.5 2 1 0 3 3 3 0 C-terminal domain of homeodomain 1 DUF883 PF05957.8 EAQ86883.1 - 5.8 7.3 8.2 78 3.7 5.5 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DDE_1 PF03184.14 EAQ86884.1 - 1.1e-57 194.7 0.0 4.9e-57 192.5 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ86884.1 - 5.3e-14 51.7 0.1 1.3e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ86884.1 - 2.4e-12 46.1 0.0 4.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EAQ86884.1 - 0.00022 20.7 0.1 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain PT PF04886.7 EAQ86884.1 - 0.22 10.8 5.5 0.5 9.7 3.8 1.6 1 0 0 1 1 1 0 PT repeat CTP_transf_1 PF01148.15 EAQ86885.1 - 7.8e-17 61.7 9.4 1.5e-12 47.7 3.9 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Aldedh PF00171.17 EAQ86886.1 - 1.1e-187 624.0 0.0 1.2e-187 623.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.5 EAQ86887.1 - 5.5e-57 192.8 0.0 8.8e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EAQ86887.1 - 2.4e-06 27.4 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ86887.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain ketoacyl-synt PF00109.21 EAQ86888.1 - 1.6e-71 240.7 1.4 1.6e-71 240.7 1.0 2.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ86888.1 - 3.6e-48 164.5 0.0 6.4e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Fungal_trans PF04082.13 EAQ86888.1 - 7.1e-18 64.4 0.2 1.7e-17 63.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ketoacyl-synt_C PF02801.17 EAQ86888.1 - 1.5e-15 57.1 1.3 4e-15 55.6 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Zn_clus PF00172.13 EAQ86888.1 - 1.9e-07 30.8 13.7 3.6e-07 29.9 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioesterase PF00975.15 EAQ86888.1 - 1.9e-07 31.5 0.3 7.8e-07 29.5 0.2 2.1 2 0 0 2 2 2 1 Thioesterase domain Thiolase_N PF00108.18 EAQ86888.1 - 0.026 13.4 1.2 0.061 12.2 0.8 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.11 EAQ86889.1 - 1.7e-37 128.9 45.1 1.7e-37 128.9 31.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ86889.1 - 1.4e-08 33.7 14.7 1.4e-08 33.7 10.2 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter Zn_clus PF00172.13 EAQ86890.1 - 3.6e-08 33.1 7.5 7.6e-08 32.1 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.13 EAQ86891.1 - 3.2e-36 124.7 1.0 1.4e-35 122.6 0.3 2.3 3 0 0 3 3 3 1 O-methyltransferase Trp_halogenase PF04820.9 EAQ86891.1 - 3.4e-26 91.8 0.2 7.5e-12 44.6 0.2 2.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EAQ86891.1 - 3.1e-14 52.8 1.3 5.2e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EAQ86891.1 - 5.2e-06 25.7 0.0 1.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ86891.1 - 5.9e-06 26.3 0.0 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ86891.1 - 0.0001 22.2 0.0 0.00057 19.8 0.0 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EAQ86891.1 - 0.00032 19.6 0.0 0.00057 18.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 EAQ86891.1 - 0.00069 18.6 0.3 0.0036 16.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ86891.1 - 0.00079 18.0 0.1 0.0013 17.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EAQ86891.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ86891.1 - 0.058 12.3 0.1 0.12 11.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EAQ86891.1 - 0.084 11.9 0.9 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family PaaX_C PF08223.6 EAQ86891.1 - 0.11 12.2 0.1 9 5.9 0.0 2.5 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Dimerisation PF08100.6 EAQ86891.1 - 0.13 12.1 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Dimerisation domain Ank_2 PF12796.2 EAQ86892.1 - 1.4e-70 233.6 4.4 1.4e-21 76.6 0.0 5.8 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ86892.1 - 3.4e-64 209.6 8.8 9.3e-11 40.9 0.0 10.7 10 1 1 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 EAQ86892.1 - 3.1e-52 174.0 8.7 2.4e-13 50.1 0.0 10.1 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ86892.1 - 1e-43 146.3 8.6 3.2e-12 46.2 0.1 9.8 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86892.1 - 3.9e-41 134.9 0.8 2.5e-05 24.0 0.0 10.0 9 1 1 10 10 10 8 Ankyrin repeat zf-C2H2_4 PF13894.1 EAQ86892.1 - 6e-05 23.0 7.0 0.072 13.4 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ86892.1 - 0.00016 21.8 7.4 0.04 14.2 0.3 2.8 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-BED PF02892.10 EAQ86892.1 - 0.027 14.2 4.9 0.056 13.2 3.4 1.5 1 0 0 1 1 1 0 BED zinc finger DUF4235 PF14019.1 EAQ86892.1 - 0.043 13.6 2.0 42 4.0 0.1 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF4235) DUF2520 PF10728.4 EAQ86892.1 - 0.069 12.6 0.4 9.1 5.7 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2520) GAGA PF09237.6 EAQ86892.1 - 4.1 7.0 6.3 0.91 9.1 0.2 2.5 2 0 0 2 2 2 0 GAGA factor zf-H2C2_2 PF13465.1 EAQ86892.1 - 5.4 7.5 7.1 25 5.4 2.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Thioesterase PF00975.15 EAQ86893.1 - 4.5e-23 82.6 0.2 1.4e-22 81.0 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EAQ86893.1 - 4.6e-09 36.4 0.1 7.7e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EAQ86893.1 - 4e-08 33.4 2.7 4e-08 33.4 1.9 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ86893.1 - 0.0054 16.5 0.1 0.0089 15.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAQ86893.1 - 0.076 12.5 0.2 0.79 9.2 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Mito_fiss_reg PF05308.6 EAQ86893.1 - 0.22 10.8 9.6 0.37 10.1 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator ketoacyl-synt PF00109.21 EAQ86894.1 - 5.3e-80 268.5 0.2 9.4e-80 267.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EAQ86894.1 - 1.1e-54 185.6 0.6 2.9e-54 184.2 0.4 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EAQ86894.1 - 2.4e-53 180.5 3.2 2.4e-53 180.5 2.3 3.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EAQ86894.1 - 4.9e-39 133.9 2.9 4.9e-39 133.9 2.0 3.8 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ86894.1 - 2.8e-30 104.6 6.5 3.7e-21 75.1 0.2 3.6 2 1 1 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EAQ86894.1 - 1.1e-18 67.0 2.8 3.4e-18 65.4 0.1 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ86894.1 - 4e-15 56.8 0.3 7.7e-14 52.6 0.0 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.16 EAQ86894.1 - 8.2e-13 48.3 0.0 1.3e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 Acyl transferase domain Thiolase_N PF00108.18 EAQ86894.1 - 7.4e-06 25.1 0.0 1.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EAQ86894.1 - 0.026 14.8 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Ank_2 PF12796.2 EAQ86895.1 - 3.3e-19 69.0 0.0 1.4e-11 44.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ86895.1 - 9.5e-17 61.0 0.0 1e-05 25.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ86895.1 - 2.8e-14 52.0 0.1 0.0025 17.5 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EAQ86895.1 - 9.3e-12 44.7 0.1 3.8e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ86895.1 - 3.1e-08 33.0 0.0 0.18 12.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat GSDH PF07995.6 EAQ86896.1 - 1.7e-117 392.2 0.1 2e-117 392.0 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EAQ86896.1 - 0.0016 18.3 0.0 0.94 9.5 0.0 3.6 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.6 EAQ86896.1 - 0.065 13.2 5.0 3.7 7.8 0.0 4.4 4 0 0 4 4 4 0 Two component regulator propeller SQS_PSY PF00494.14 EAQ86897.1 - 0.01 15.1 0.5 0.74 9.0 0.2 2.4 1 1 1 2 2 2 0 Squalene/phytoene synthase cobW PF02492.14 EAQ86898.1 - 2.1e-25 89.1 4.0 2.7e-15 56.2 0.2 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EAQ86898.1 - 1.2e-18 66.5 0.7 7.7e-14 51.1 0.0 2.9 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 EAQ86898.1 - 0.0058 14.7 6.5 0.0083 14.2 4.5 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.8 EAQ86898.1 - 0.089 12.6 8.7 0.13 12.1 6.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EAQ86898.1 - 0.11 10.3 10.4 0.16 9.8 7.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2443 PF10398.4 EAQ86898.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) SDA1 PF05285.7 EAQ86898.1 - 0.29 10.3 8.6 0.48 9.6 6.0 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 EAQ86898.1 - 0.89 8.7 6.7 1.4 8.1 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 EAQ86898.1 - 1.3 7.0 5.7 2 6.4 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 EAQ86898.1 - 2.8 7.5 11.0 4.5 6.9 7.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CLP_protease PF00574.18 EAQ86899.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Clp protease SnoaL PF07366.7 EAQ86900.1 - 0.061 12.9 0.2 2.5 7.6 0.1 2.1 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase Band_7 PF01145.20 EAQ86901.1 - 5.7e-17 62.1 2.2 5.5e-15 55.7 0.2 2.3 1 1 1 2 2 2 2 SPFH domain / Band 7 family Band_7_1 PF13421.1 EAQ86901.1 - 0.12 11.9 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DEAD PF00270.24 EAQ86902.1 - 5.8e-37 126.7 0.0 1.2e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ86902.1 - 1e-19 70.1 0.0 2.5e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EAQ86902.1 - 1.1e-19 69.7 0.0 2.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EAQ86902.1 - 0.00023 21.0 0.0 0.00061 19.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EAQ86902.1 - 0.0065 16.2 0.1 0.12 12.0 0.1 2.7 1 1 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EAQ86903.1 - 0.51 10.2 5.9 0.22 11.4 1.3 2.2 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.7 EAQ86903.1 - 0.54 10.1 5.5 0.78 9.5 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2570 PF10828.3 EAQ86903.1 - 7.1 6.2 9.4 15 5.2 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) OmpH PF03938.9 EAQ86903.1 - 8 6.3 16.2 14 5.5 11.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CmcH_NodU PF02543.10 EAQ86904.1 - 0.028 13.5 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase DUF310 PF03750.8 EAQ86905.1 - 0.0072 16.5 1.9 0.02 15.0 1.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF310) DUF3166 PF11365.3 EAQ86905.1 - 0.01 16.2 3.3 0.01 16.2 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) HALZ PF02183.13 EAQ86905.1 - 0.012 15.3 17.1 1.2 8.9 1.0 4.4 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF972 PF06156.8 EAQ86905.1 - 0.059 13.7 18.5 1.3 9.3 5.8 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Allexi_40kDa PF05549.6 EAQ86905.1 - 0.24 10.6 1.8 0.38 10.0 0.9 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein OmpH PF03938.9 EAQ86905.1 - 2.9 7.8 16.6 1 9.2 5.3 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EAQ86905.1 - 4.4 5.6 6.8 2.4 6.4 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) UPF0242 PF06785.6 EAQ86906.1 - 0.17 10.5 7.6 0.35 9.5 5.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) ORF6C PF10552.4 EAQ86906.1 - 0.25 11.0 5.4 0.57 9.9 3.7 1.5 1 0 0 1 1 1 0 ORF6C domain Hormone_1 PF00103.15 EAQ86906.1 - 0.26 10.5 6.8 2.2 7.5 0.1 2.4 1 1 1 2 2 2 0 Somatotropin hormone family Herpes_U30 PF04523.8 EAQ86906.1 - 0.38 8.1 5.1 0.49 7.7 3.5 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF2935 PF11155.3 EAQ86906.1 - 0.49 10.5 2.6 0.99 9.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3763 PF12592.3 EAQ86906.1 - 4.2 7.0 6.0 1.4 8.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Nucleo_P87 PF07267.6 EAQ86906.1 - 5.4 5.5 18.5 7.4 5.1 12.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TMPIT PF07851.8 EAQ86906.1 - 7.7 5.4 5.5 12 4.8 3.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Smg4_UPF3 PF03467.10 EAQ86907.1 - 4.3e-35 121.2 0.1 4.3e-35 121.2 0.0 2.3 2 1 0 2 2 2 1 Smg-4/UPF3 family Metallophos PF00149.23 EAQ86908.1 - 6.2e-38 130.2 0.0 6.1e-33 113.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase NOSIC PF08060.8 EAQ86908.1 - 0.12 12.2 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 NOSIC (NUC001) domain Thr_synth_N PF14821.1 EAQ86909.1 - 2.2e-27 94.9 0.0 5.1e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EAQ86909.1 - 5.6e-19 68.5 0.0 4.7e-18 65.4 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.15 EAQ86910.1 - 6.8e-10 38.6 0.0 7.6e-06 25.5 0.0 2.9 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain WD40 PF00400.27 EAQ86911.1 - 0.00011 21.9 0.6 0.011 15.6 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Adaptin_N PF01602.15 EAQ86912.1 - 1.2e-112 376.9 0.9 1.6e-112 376.5 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EAQ86912.1 - 1.3e-47 160.3 0.0 3.6e-47 158.9 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EAQ86912.1 - 6.8e-21 74.7 0.0 1.3e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Methyltransf_11 PF08241.7 EAQ86913.1 - 5.9e-10 39.5 0.0 1.3e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ86913.1 - 6.9e-08 32.8 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ86913.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ86913.1 - 6.9e-05 22.4 0.0 0.00016 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ86913.1 - 0.0083 16.6 0.0 0.028 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ86913.1 - 0.0089 16.3 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ86913.1 - 0.024 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family P16-Arc PF04699.9 EAQ86914.1 - 1e-58 197.7 0.0 1.2e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Acetyltransf_8 PF13523.1 EAQ86916.1 - 0.096 12.5 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIF1 PF05970.9 EAQ86918.1 - 6.4e-15 54.9 0.0 9.9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ86918.1 - 5.6e-05 23.2 0.0 0.00039 20.5 0.0 2.3 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ86918.1 - 0.021 14.9 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 Helicase associated domain TAF4 PF05236.9 EAQ86919.1 - 4.9e-06 26.0 10.2 0.015 14.5 1.5 4.2 5 0 0 5 5 5 3 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 EAQ86920.1 - 1.5e-78 263.1 0.0 5.5e-76 254.6 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EAQ86920.1 - 9.9e-32 109.5 0.0 2.1e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EAQ86920.1 - 1.2e-14 54.4 0.6 3.5e-14 52.9 0.4 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAQ86920.1 - 1.3e-11 44.3 0.5 2.3e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EAQ86920.1 - 1.1e-07 31.5 0.1 2.2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EAQ86920.1 - 5.7e-06 26.1 0.2 1.7e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Uds1 PF15456.1 EAQ86921.1 - 2.9e-43 146.7 11.5 2.9e-43 146.7 8.0 9.2 5 2 4 9 9 9 2 Up-regulated During Septation MOSC PF03473.12 EAQ86921.1 - 0.0091 15.4 0.0 0.044 13.2 0.0 2.3 1 0 0 1 1 1 1 MOSC domain Prenyltransf PF01255.14 EAQ86923.1 - 5.2e-83 277.5 0.0 1e-82 276.5 0.0 1.4 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 EAQ86923.1 - 8.1e-07 28.6 1.0 1.8e-06 27.5 0.7 1.6 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EAQ86923.1 - 3.4e-06 27.2 0.1 8.1e-05 22.8 0.1 2.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding F-box-like PF12937.2 EAQ86924.1 - 0.0031 17.2 0.1 0.013 15.2 0.1 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EAQ86924.1 - 0.0033 17.3 2.4 1.2 9.4 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EAQ86924.1 - 0.037 13.6 2.7 0.72 9.5 0.0 3.8 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EAQ86924.1 - 0.091 12.8 3.6 29 5.2 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat BCL9 PF11502.3 EAQ86924.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein V_ATPase_I PF01496.14 EAQ86925.1 - 1.3e-302 1005.3 0.0 1.5e-302 1005.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EAQ86925.1 - 0.039 13.4 8.3 0.37 10.1 0.2 2.5 2 1 0 2 2 2 0 Intermediate filament protein DUF3584 PF12128.3 EAQ86925.1 - 0.054 10.8 2.7 0.083 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 EAQ86925.1 - 0.063 13.1 2.4 3.2 7.5 0.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EAQ86925.1 - 0.18 10.1 1.1 1.5 7.1 0.2 2.0 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.7 EAQ86925.1 - 0.27 10.9 2.6 7.1 6.3 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Cortex-I_coil PF09304.5 EAQ86925.1 - 0.47 10.5 2.9 13 5.9 0.1 3.0 3 0 0 3 3 3 0 Cortexillin I, coiled coil DUF3552 PF12072.3 EAQ86925.1 - 0.55 9.4 3.9 7.6 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4140 PF13600.1 EAQ86925.1 - 0.71 10.3 3.9 6 7.3 0.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EAQ86925.1 - 0.82 9.2 8.3 1.2 8.6 0.2 3.3 3 0 0 3 3 3 0 IncA protein DivIC PF04977.10 EAQ86925.1 - 1.4 8.5 5.6 0.87 9.1 0.2 2.9 2 0 0 2 2 2 0 Septum formation initiator Tcp11 PF05794.8 EAQ86926.1 - 1.9e-78 264.1 0.0 3.6e-76 256.6 0.3 2.1 2 0 0 2 2 2 2 T-complex protein 11 DDE_3 PF13358.1 EAQ86930.1 - 3.4e-15 56.0 0.2 5.7e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ86930.1 - 4.6e-06 26.6 0.0 9.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EAQ86930.1 - 0.00015 21.8 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EAQ86930.1 - 0.0013 18.3 0.3 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain rve PF00665.21 EAQ86930.1 - 0.0015 18.6 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_38 PF13936.1 EAQ86930.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID-18kDa PF02269.11 EAQ86931.1 - 6.7e-20 70.6 0.0 1.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EAQ86931.1 - 8.8e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 EAQ86931.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EAQ86931.1 - 0.0057 16.7 0.1 0.013 15.6 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAQ86931.1 - 0.0063 16.5 0.0 0.0063 16.5 0.0 2.3 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CD99L2 PF12301.3 EAQ86931.1 - 0.064 12.9 1.3 0.08 12.6 0.9 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 TFIID_20kDa PF03847.8 EAQ86931.1 - 0.08 13.2 0.1 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Macro PF01661.16 EAQ86932.1 - 3e-16 59.4 0.0 5.2e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Macro domain EamA PF00892.15 EAQ86933.1 - 2.7e-16 59.7 26.6 4.9e-11 42.7 4.8 2.8 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAQ86933.1 - 7.3e-05 22.9 5.3 7.3e-05 22.9 3.6 3.7 2 2 1 4 4 4 1 Multidrug resistance efflux transporter UAA PF08449.6 EAQ86933.1 - 7.4e-05 21.8 9.2 0.0028 16.6 1.1 2.1 1 1 1 2 2 2 2 UAA transporter family TIP49 PF06068.8 EAQ86934.1 - 1.7e-130 435.3 1.1 1e-109 366.9 0.2 2.1 1 1 1 2 2 2 2 TIP49 C-terminus AAA PF00004.24 EAQ86934.1 - 9.3e-11 42.0 0.1 2.4e-07 31.0 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAQ86934.1 - 2.2e-06 26.8 0.2 0.00032 19.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ86934.1 - 7.7e-05 22.3 0.2 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EAQ86934.1 - 0.00098 19.1 0.1 0.0022 17.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ86934.1 - 0.0021 17.4 0.0 0.0067 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAQ86934.1 - 0.0039 16.3 0.3 0.0094 15.0 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EAQ86934.1 - 0.01 15.2 0.3 0.023 14.1 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EAQ86934.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 EAQ86934.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EAQ86934.1 - 0.021 15.1 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAQ86934.1 - 0.028 13.5 0.5 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.9 EAQ86934.1 - 0.035 13.8 0.1 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 EAQ86934.1 - 0.045 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EAQ86934.1 - 0.052 14.3 0.1 0.11 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 EAQ86934.1 - 0.094 12.2 0.1 0.37 10.3 0.0 2.0 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Mg_chelatase PF01078.16 EAQ86934.1 - 0.13 11.4 0.1 0.47 9.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EAQ86934.1 - 0.14 12.3 0.1 0.47 10.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain HMG_box PF00505.14 EAQ86935.1 - 1.2e-22 79.8 0.7 2.4e-22 78.9 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ86935.1 - 2.1e-07 31.2 0.4 4.2e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain Dynactin PF12455.3 EAQ86936.1 - 5.5e-94 314.1 9.4 5.5e-94 314.1 6.5 3.1 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EAQ86936.1 - 3.6e-22 77.8 0.1 6e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.4 EAQ86936.1 - 7.3e-05 22.1 21.0 7.3e-05 22.1 14.5 4.0 2 2 2 4 4 4 1 Uncharacterized coiled-coil protein (DUF2353) DBC1 PF14443.1 EAQ86936.1 - 0.013 14.9 0.0 0.047 13.2 0.0 1.9 1 0 0 1 1 1 0 DBC1 SRP19 PF01922.12 EAQ86937.1 - 2.3e-28 98.5 0.3 5.6e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 SRP19 protein Pex14_N PF04695.8 EAQ86937.1 - 0.035 14.1 3.0 0.76 9.8 3.2 2.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3729 PF12526.3 EAQ86937.1 - 0.16 13.3 0.3 0.16 13.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Myosin_tail_1 PF01576.14 EAQ86938.1 - 0.047 11.4 1.9 0.06 11.0 1.3 1.0 1 0 0 1 1 1 0 Myosin tail APG6 PF04111.7 EAQ86938.1 - 0.1 11.5 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4635 PF15466.1 EAQ86938.1 - 0.12 11.6 0.7 0.23 10.7 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) CDP-OH_P_transf PF01066.16 EAQ86940.1 - 4e-14 52.7 1.8 4e-14 52.7 1.3 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DDE_3 PF13358.1 EAQ86941.1 - 7.6e-18 64.6 0.1 1.3e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ86941.1 - 2.5e-07 30.6 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Transposase rve PF00665.21 EAQ86941.1 - 0.00059 19.9 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 EAQ86941.1 - 0.0029 17.1 0.1 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain DUF3007 PF11460.3 EAQ86941.1 - 0.026 14.6 0.3 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) HTH_38 PF13936.1 EAQ86941.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain OMPdecase PF00215.19 EAQ86943.1 - 2.2e-88 295.4 0.3 3.3e-88 294.8 0.2 1.3 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Sporozoite_P67 PF05642.6 EAQ86943.1 - 0.00013 20.0 3.2 0.00016 19.7 2.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen BAF1_ABF1 PF04684.8 EAQ86943.1 - 0.0056 15.5 13.0 0.0079 15.0 9.0 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 EAQ86943.1 - 0.012 13.8 13.8 0.014 13.6 9.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Atg14 PF10186.4 EAQ86943.1 - 0.083 11.8 5.2 0.04 12.8 1.8 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 eIF-3_zeta PF05091.7 EAQ86943.1 - 0.11 11.0 9.5 0.16 10.5 6.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Androgen_recep PF02166.11 EAQ86943.1 - 0.57 8.9 8.5 0.76 8.5 5.9 1.2 1 0 0 1 1 1 0 Androgen receptor FixO PF02433.10 EAQ86943.1 - 0.6 9.4 5.1 0.92 8.8 3.5 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO FimP PF09766.4 EAQ86943.1 - 1.5 7.7 14.0 2.1 7.3 9.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein Hid1 PF12722.2 EAQ86943.1 - 2.1 5.9 6.1 3.1 5.3 4.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3043 PF11241.3 EAQ86943.1 - 2.3 7.8 7.7 4.1 6.9 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DDHD PF02862.12 EAQ86943.1 - 2.7 7.7 7.6 4 7.1 5.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.1 EAQ86943.1 - 5.2 5.9 12.1 3.2 6.6 7.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PBP_sp32 PF07222.7 EAQ86943.1 - 5.3 6.1 10.7 8.1 5.5 7.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4175 PF13779.1 EAQ86943.1 - 7.3 4.1 25.1 10 3.6 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Fungal_trans PF04082.13 EAQ86944.1 - 6e-11 41.7 0.0 5.5e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ86944.1 - 2.8e-07 30.3 12.0 5.2e-07 29.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNP_UDP_1 PF01048.15 EAQ86945.1 - 7.2e-08 31.6 0.0 3.8e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EAQ86945.1 - 1.5e-06 27.9 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ86945.1 - 0.061 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 EAQ86946.1 - 0.71 8.0 9.0 0.81 7.8 6.2 1.0 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 EAQ86946.1 - 3.4 6.2 13.8 4.5 5.8 9.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_pol_viral_N PF00242.12 EAQ86946.1 - 4.6 6.1 7.0 4.5 6.2 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hamartin PF04388.7 EAQ86946.1 - 5.2 5.6 6.7 5.3 5.5 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein WD40 PF00400.27 EAQ86947.1 - 2.6e-181 581.8 49.0 2.8e-14 52.3 0.1 13.6 13 0 0 13 13 13 13 WD domain, G-beta repeat Nup160 PF11715.3 EAQ86947.1 - 1.9e-16 59.3 38.4 0.057 11.5 0.0 12.2 1 1 6 11 11 11 11 Nucleoporin Nup120/160 NACHT PF05729.7 EAQ86947.1 - 1.3e-14 54.1 0.3 2.4e-14 53.3 0.2 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EAQ86947.1 - 3.9e-11 42.3 30.2 11 5.8 0.1 12.7 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EAQ86947.1 - 9.9e-10 37.7 7.5 5.2 5.7 0.0 10.3 1 1 10 11 11 11 2 Nup133 N terminal like Proteasome_A_N PF10584.4 EAQ86947.1 - 5.5e-06 25.5 3.0 1.6e+02 1.7 0.0 10.0 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature NYD-SP28_assoc PF14775.1 EAQ86947.1 - 7.8e-05 22.3 17.0 1.1e+02 2.5 0.0 11.5 13 0 0 13 13 13 0 Sperm tail C-terminal domain Pectate_lyase22 PF14583.1 EAQ86947.1 - 0.00014 20.5 0.0 16 3.8 0.0 4.8 1 1 3 5 5 5 0 Oligogalacturonate lyase Cytochrom_D1 PF02239.11 EAQ86947.1 - 0.0005 18.4 4.7 1 7.5 0.0 4.6 1 1 3 6 6 6 1 Cytochrome D1 heme domain DUF2075 PF09848.4 EAQ86947.1 - 0.037 13.0 0.0 0.12 11.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAQ86947.1 - 0.073 13.2 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAQ86947.1 - 0.15 12.2 0.0 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase GATase PF00117.23 EAQ86947.1 - 0.32 10.4 0.0 0.63 9.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I CENP-N PF05238.8 EAQ86948.1 - 1.6e-93 313.9 0.0 1.4e-92 310.8 0.0 1.8 1 1 1 2 2 2 2 Kinetochore protein CHL4 like TatD_DNase PF01026.16 EAQ86949.1 - 3.5e-07 29.6 0.0 5.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TFIIA PF03153.8 EAQ86949.1 - 0.048 13.5 6.8 0.064 13.1 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.7 EAQ86949.1 - 0.4 9.0 7.4 0.51 8.6 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family RR_TM4-6 PF06459.7 EAQ86949.1 - 1.3 8.8 5.7 2 8.2 4.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.14 EAQ86949.1 - 9.8 6.6 11.2 0.34 11.3 1.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribonuc_red_lgC PF02867.10 EAQ86950.1 - 1.6e-220 733.2 0.0 2.2e-220 732.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EAQ86950.1 - 6.2e-24 83.6 0.0 1.4e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EAQ86950.1 - 1.1e-17 64.1 0.1 5.5e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EAQ86950.1 - 0.051 11.6 0.0 0.081 10.9 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MMR_HSR1_C PF08438.5 EAQ86950.1 - 0.057 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 GTPase of unknown function C-terminal CFEM PF05730.6 EAQ86951.1 - 6.3e-09 35.5 1.7 1.1e-08 34.7 1.1 1.4 1 0 0 1 1 1 1 CFEM domain Glyco_trans_4_4 PF13579.1 EAQ86952.1 - 5.6e-12 46.0 1.3 5.6e-12 46.0 0.9 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EAQ86952.1 - 7.4e-10 38.8 0.1 4.8e-09 36.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.15 EAQ86952.1 - 0.00028 20.3 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.20 EAQ86953.1 - 5.2e-53 179.8 0.1 8.6e-38 129.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86953.1 - 6.2e-21 74.6 0.1 3.4e-19 68.9 0.1 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ86953.1 - 0.0001 21.4 0.0 0.00038 19.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ86953.1 - 0.0034 17.1 0.3 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Reo_sigmaC PF04582.7 EAQ86955.1 - 0.00071 18.8 0.2 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Macoilin PF09726.4 EAQ86955.1 - 0.0088 14.3 9.0 0.0022 16.3 3.2 1.9 2 0 0 2 2 2 1 Transmembrane protein TPR_MLP1_2 PF07926.7 EAQ86955.1 - 0.021 14.5 2.8 0.048 13.4 1.9 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2935 PF11155.3 EAQ86955.1 - 0.028 14.4 2.2 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Snapin_Pallidin PF14712.1 EAQ86955.1 - 0.034 14.4 1.4 0.13 12.6 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Tropomyosin PF00261.15 EAQ86955.1 - 0.035 13.2 12.0 0.0096 15.0 5.0 2.1 2 0 0 2 2 2 0 Tropomyosin CSTF_C PF14304.1 EAQ86955.1 - 0.25 10.6 1.8 14 5.0 0.1 3.1 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal DUF4446 PF14584.1 EAQ86955.1 - 0.32 10.8 1.3 0.75 9.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Lzipper-MIP1 PF14389.1 EAQ86955.1 - 0.44 10.6 7.2 9.5 6.4 0.1 3.7 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 FliD_N PF02465.13 EAQ86955.1 - 0.61 10.4 5.2 0.41 11.0 1.6 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.5 EAQ86955.1 - 1.4 8.9 7.3 2.7 8.0 2.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 EAQ86955.1 - 3.9 7.2 13.8 0.13 12.0 2.2 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding RRM_1 PF00076.17 EAQ86956.1 - 1.3e-41 140.1 0.6 8.2e-19 67.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ86956.1 - 7.2e-33 112.3 0.1 1.2e-17 63.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EAQ86956.1 - 1.8e-26 92.1 0.1 4.5e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EAQ86956.1 - 7.6e-20 70.5 0.0 1.8e-08 34.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAQ86956.1 - 0.012 15.4 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif Cyt-b5 PF00173.23 EAQ86957.1 - 9.3e-19 67.0 0.5 4.7e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EAQ86957.1 - 1.2e-08 35.3 20.7 2e-08 34.6 13.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EAQ86957.1 - 0.011 15.2 0.6 0.065 12.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.8 EAQ86957.1 - 0.12 12.4 0.9 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Het-C PF07217.6 EAQ86958.1 - 3.8e-294 976.5 0.0 4.4e-294 976.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Baculo_PEP_C PF04513.7 EAQ86958.1 - 0.24 11.1 0.0 0.47 10.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PP2C PF00481.16 EAQ86959.1 - 3e-17 62.8 0.0 1e-10 41.4 0.0 2.6 3 0 0 3 3 3 2 Protein phosphatase 2C BTB PF00651.26 EAQ86960.1 - 0.18 11.8 0.5 8 6.4 0.0 2.8 3 0 0 3 3 3 0 BTB/POZ domain FTR1 PF03239.9 EAQ86961.1 - 1e-49 169.1 9.2 6.1e-27 94.3 0.9 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Cupin_5 PF06172.6 EAQ86961.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily (DUF985) DUF3112 PF11309.3 EAQ86961.1 - 0.16 11.7 4.3 0.67 9.7 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF4282 PF14110.1 EAQ86961.1 - 1.9 8.7 14.3 1.6 8.9 3.3 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) Yip1 PF04893.12 EAQ86961.1 - 2.5 7.5 13.4 0.049 13.1 2.5 2.3 1 1 0 2 2 2 0 Yip1 domain Cu-oxidase_3 PF07732.10 EAQ86962.1 - 6.3e-43 145.2 2.1 1.7e-42 143.8 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EAQ86962.1 - 5.8e-39 133.5 0.7 3.8e-33 114.6 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ86962.1 - 6e-11 42.0 2.4 0.00028 20.3 0.7 3.1 2 1 0 2 2 2 2 Multicopper oxidase DUF1521 PF07481.6 EAQ86963.1 - 0.039 13.6 0.1 0.29 10.8 0.1 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1521) PGAP1 PF07819.8 EAQ86964.1 - 0.00043 19.9 0.2 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EAQ86964.1 - 0.0026 17.0 0.1 0.0033 16.7 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EAQ86964.1 - 0.005 16.7 2.0 0.0076 16.1 1.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EAQ86965.1 - 2.5e-58 197.7 0.0 3.3e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 EAQ86966.1 - 8e-39 131.4 19.0 8.2e-10 38.4 0.0 5.6 1 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ86966.1 - 3.2e-26 90.4 17.8 3.8e-07 29.8 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ86966.1 - 1.7e-08 34.9 9.3 0.2 12.3 3.8 5.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ86966.1 - 4.3e-08 32.8 32.5 0.16 12.4 0.0 8.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ86966.1 - 5e-05 23.5 5.7 1.6 9.0 0.1 6.2 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ86966.1 - 5.3e-05 23.4 22.5 3.2 8.6 0.0 8.2 7 1 1 8 8 7 1 Tetratricopeptide repeat AAA_22 PF13401.1 EAQ86966.1 - 0.0002 21.5 0.0 0.0008 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.1 EAQ86966.1 - 0.00048 19.7 1.9 5.6 6.6 0.0 5.0 4 2 1 5 5 5 1 TPR repeat NACHT PF05729.7 EAQ86966.1 - 0.0061 16.2 0.0 0.019 14.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 EAQ86966.1 - 0.013 15.3 15.1 0.27 11.2 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ86966.1 - 0.013 15.1 0.1 43 4.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ86966.1 - 0.041 12.7 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TPR_1 PF00515.23 EAQ86966.1 - 0.14 11.8 8.8 1.3 8.7 0.2 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EAQ86966.1 - 0.19 11.8 0.0 24 5.1 0.0 3.8 5 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EAQ86966.1 - 0.69 10.2 2.4 45 4.6 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ86966.1 - 0.7 10.4 8.4 42 4.9 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ86966.1 - 1.2 9.1 14.9 56 3.8 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat bZIP_2 PF07716.10 EAQ86967.1 - 4.2e-12 45.6 8.4 7.1e-12 44.9 5.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EAQ86967.1 - 8.5e-06 25.6 8.0 1.7e-05 24.6 5.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EAQ86967.1 - 0.065 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family XhlA PF10779.4 EAQ86967.1 - 0.11 12.3 2.6 0.21 11.5 1.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA PAT1 PF09770.4 EAQ86968.1 - 2.7 6.1 8.7 3.1 5.9 6.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EAQ86968.1 - 4.3 7.1 12.4 5.2 6.8 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.16 EAQ86969.1 - 1.9e-35 122.4 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EAQ86969.1 - 0.018 14.2 0.0 0.057 12.5 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase VWA PF00092.23 EAQ86970.1 - 1.6e-09 37.7 0.0 3.7e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EAQ86970.1 - 3.4e-08 33.8 0.0 6.3e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EAQ86970.1 - 5.9e-05 22.9 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus LRR_4 PF12799.2 EAQ86971.1 - 1.4e-27 94.8 42.8 1.6e-07 30.7 3.1 8.1 4 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ86971.1 - 2.1e-18 65.8 43.5 2.7e-05 23.8 1.1 6.4 4 2 3 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EAQ86971.1 - 5.2e-09 34.8 44.4 0.044 13.8 0.5 11.9 11 2 0 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.1 EAQ86971.1 - 3.3e-08 33.3 10.8 0.00068 19.2 0.6 3.5 2 1 1 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 EAQ86971.1 - 0.00019 21.0 42.7 5.7 7.5 0.1 11.5 12 1 1 13 13 13 5 Leucine rich repeat LRR_6 PF13516.1 EAQ86971.1 - 0.00022 20.9 37.1 1.2 9.4 0.0 9.5 8 2 1 9 9 9 3 Leucine Rich repeat IPK PF03770.11 EAQ86974.1 - 3.1e-58 196.6 0.0 6.4e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 EAQ86974.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 ATG27 PF09451.5 EAQ86976.1 - 7.1e-27 94.2 11.4 3e-26 92.2 6.2 2.5 1 1 1 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.13 EAQ86976.1 - 0.068 12.9 0.1 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Cation-independent mannose-6-phosphate receptor repeat Spt20 PF12090.3 EAQ86977.1 - 1.7e-48 164.3 0.0 1.7e-48 164.3 0.0 6.5 3 2 0 4 4 4 1 Spt20 family Hexapep PF00132.19 EAQ86979.1 - 2.1e-08 33.3 0.1 0.0058 16.0 0.0 2.8 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EAQ86979.1 - 3.6e-05 23.8 0.0 6.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EAQ86979.1 - 0.00063 19.1 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EAQ86979.1 - 0.083 12.4 8.2 0.51 9.9 1.8 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EAQ86979.1 - 0.2 10.1 1.0 0.68 8.4 0.7 1.7 1 1 1 2 2 2 0 L-fucokinase zf-C2H2 PF00096.21 EAQ86981.1 - 0.00069 19.8 4.6 0.0053 17.0 0.4 2.8 1 1 1 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ86981.1 - 0.003 17.7 1.6 0.011 16.0 0.2 2.6 1 1 1 2 2 2 1 C2H2-type zinc finger LRR_6 PF13516.1 EAQ86983.1 - 0.0048 16.8 1.3 13 6.2 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 EAQ86983.1 - 0.024 14.2 4.9 21 4.8 0.0 4.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EAQ86983.1 - 0.057 13.4 2.2 14 6.2 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat Mito_carr PF00153.22 EAQ86984.1 - 1.8e-28 98.0 0.3 1.7e-14 53.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.8 EAQ86985.1 - 8.4e-75 251.6 0.3 1.6e-74 250.6 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EAQ86985.1 - 5.6e-07 29.3 0.1 0.00048 19.9 0.0 3.3 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EAQ86985.1 - 0.0054 16.2 0.3 3.1 7.3 0.0 4.2 4 0 0 4 4 4 1 TFIIE alpha subunit ATP-synt_Eps PF04627.8 EAQ86986.1 - 2.8e-20 71.5 1.6 9e-20 69.9 1.1 1.9 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 EAQ86986.1 - 2.7e-14 53.1 0.2 1.8e-13 50.4 0.1 2.1 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAQ86986.1 - 7e-14 51.9 0.0 3.5e-13 49.6 0.0 2.2 4 0 0 4 4 4 1 Peptidase M16 inactive domain Mak10 PF04112.8 EAQ86987.1 - 1.9e-21 75.9 0.1 3.4e-18 65.4 0.0 2.4 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.22 EAQ86988.1 - 9.9e-41 137.3 0.1 1.5e-16 59.8 0.0 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EAQ86988.1 - 0.0017 18.1 0.3 0.0043 16.8 0.1 1.8 2 0 0 2 2 2 1 UcrQ family Abp2 PF09441.5 EAQ86989.1 - 3.4e-91 303.8 0.0 5.4e-91 303.2 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 Actin PF00022.14 EAQ86991.1 - 3.9e-15 55.1 0.0 7.8e-14 50.8 0.0 2.7 2 1 0 2 2 2 1 Actin XPG_I PF00867.13 EAQ86992.1 - 7.5e-25 86.8 0.0 1.5e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAQ86992.1 - 0.00066 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain SWIB PF02201.13 EAQ86993.1 - 3.7e-11 42.5 0.0 7.3e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 EAQ86994.1 - 4.6e-47 160.3 0.6 1.9e-42 145.2 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ86994.1 - 1.6e-24 86.3 0.1 3.4e-24 85.3 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ86994.1 - 0.00027 20.0 0.3 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAQ86994.1 - 0.00038 19.5 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ86994.1 - 0.0025 17.6 0.1 0.0082 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EAQ86994.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EAQ86994.1 - 0.16 10.7 0.1 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DJ-1_PfpI_N PF13587.1 EAQ86996.1 - 0.092 12.2 0.1 0.29 10.6 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family tRNA-synt_1 PF00133.17 EAQ86998.1 - 1.5e-224 746.4 0.0 2.5e-224 745.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAQ86998.1 - 3.7e-27 94.9 0.0 1.5e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAQ86998.1 - 9.3e-20 70.6 0.6 1.1e-08 34.1 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EAQ86998.1 - 0.067 12.2 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Sfi1 PF08457.5 EAQ86999.1 - 1.4e-174 581.7 83.1 1.1e-170 568.9 53.9 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein KOW PF00467.24 EAQ87000.1 - 1.5e-06 27.7 0.6 6.2e-06 25.7 0.5 2.0 2 0 0 2 2 2 1 KOW motif Mo25 PF08569.6 EAQ87001.1 - 1.6e-127 425.2 0.0 1.8e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Mo25-like F-box-like PF12937.2 EAQ87003.1 - 1.8e-06 27.5 1.8 1.1e-05 25.0 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAQ87003.1 - 0.069 12.8 1.4 0.69 9.6 0.4 3.0 2 1 0 2 2 2 0 F-box domain DUF2048 PF09752.4 EAQ87003.1 - 0.078 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Ala_racemase_N PF01168.15 EAQ87004.1 - 2.9e-15 56.4 0.0 5e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain MtrB PF05440.7 EAQ87005.1 - 1.4 9.0 5.1 4.2 7.4 0.0 4.4 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B tRNA-synt_2b PF00587.20 EAQ87006.1 - 3.9e-22 78.6 0.0 5.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EAQ87006.1 - 1.1e-12 47.8 2.1 7.8e-12 45.1 1.5 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain bZIP_Maf PF03131.12 EAQ87006.1 - 0.091 13.0 0.5 0.091 13.0 0.3 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor MS_channel PF00924.13 EAQ87007.1 - 6.3e-16 58.3 1.7 1.2e-15 57.3 1.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.1 EAQ87007.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 EAQ87007.1 - 0.012 14.9 0.1 0.028 13.7 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EAQ87007.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EAQ87007.1 - 0.033 14.3 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Vma12 PF11712.3 EAQ87007.1 - 1.7 8.3 12.8 0.11 12.1 0.2 2.7 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ODV-E18 PF10717.4 EAQ87007.1 - 7.4 6.0 6.6 0.74 9.2 0.4 2.4 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DLH PF01738.13 EAQ87008.1 - 8.4e-19 67.7 0.0 3.3e-18 65.7 0.0 1.8 1 1 1 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EAQ87008.1 - 0.00037 20.2 0.0 0.0046 16.6 0.0 1.9 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 EAQ87008.1 - 0.0023 17.7 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EAQ87008.1 - 0.026 13.0 0.0 0.042 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HSP70 PF00012.15 EAQ87009.1 - 4.9e-268 890.0 3.3 5.6e-268 889.8 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ87009.1 - 1.7e-17 63.0 0.0 3e-16 58.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EAQ87009.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EAQ87009.1 - 0.01 14.9 0.0 0.042 12.9 0.0 1.9 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EAQ87009.1 - 0.02 14.7 1.6 0.88 9.4 1.1 3.3 1 1 0 1 1 1 0 Cell division protein FtsA StbA PF06406.6 EAQ87009.1 - 0.051 12.5 0.0 0.094 11.6 0.0 1.4 1 0 0 1 1 1 0 StbA protein DUF4404 PF14357.1 EAQ87009.1 - 1.8 9.0 5.2 5.1 7.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3128 PF11326.3 EAQ87010.1 - 5.4e-28 96.9 0.8 9.5e-28 96.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 EAQ87011.1 - 1.8e-168 560.5 0.8 1.8e-168 560.5 0.6 1.7 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 EAQ87011.1 - 0.0001 21.8 0.3 0.00056 19.4 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ87011.1 - 0.003 17.3 0.2 0.0079 16.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EAQ87011.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Arch_ATPase PF01637.13 EAQ87011.1 - 0.015 15.0 0.7 0.1 12.2 0.0 2.6 3 1 0 3 3 3 0 Archaeal ATPase RRM_6 PF14259.1 EAQ87011.1 - 0.058 13.3 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mif2_N PF15624.1 EAQ87012.1 - 3.3e-36 124.8 1.5 3.3e-36 124.8 1.0 3.5 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EAQ87012.1 - 5.6e-34 115.9 0.5 9e-34 115.3 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EAQ87012.1 - 0.00025 20.4 0.0 0.0007 19.0 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EAQ87012.1 - 0.022 14.4 0.3 0.21 11.1 0.0 2.7 2 1 1 3 3 3 0 Cupin RNase_HII PF01351.13 EAQ87013.1 - 3.2e-44 150.9 0.0 4.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.7 EAQ87014.1 - 1e-298 992.4 0.0 1.3e-298 992.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EAQ87014.1 - 7.7e-08 31.6 0.1 1.3e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EAQ87014.1 - 4.9e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 EAQ87014.1 - 2.8e-05 24.1 0.0 8.1e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EAQ87014.1 - 7.5e-05 22.6 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ87014.1 - 0.0016 18.9 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EAQ87014.1 - 0.076 12.0 0.1 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin Cys_Met_Meta_PP PF01053.15 EAQ87014.1 - 0.09 11.0 0.1 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Fructosamin_kin PF03881.9 EAQ87015.1 - 5.7e-16 58.3 0.0 6.8e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAQ87015.1 - 8e-05 22.4 0.0 9.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Med18 PF09637.5 EAQ87016.1 - 2.4e-06 27.2 0.0 0.0009 18.8 0.0 2.2 1 1 1 2 2 2 2 Med18 protein Fungal_trans_2 PF11951.3 EAQ87016.1 - 0.00014 20.6 0.2 0.00027 19.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ87016.1 - 0.0053 16.6 4.3 0.013 15.3 3.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 EAQ87017.1 - 6.9e-34 117.9 0.1 8.9e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EAQ87017.1 - 2e-09 37.1 0.4 2.6e-06 26.9 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EAQ87017.1 - 9.2e-07 29.1 1.1 3.3e-05 24.0 0.7 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EAQ87017.1 - 7.6e-06 25.6 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EAQ87017.1 - 0.00032 19.7 0.0 0.0008 18.4 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase HET PF06985.6 EAQ87018.1 - 1.2e-19 70.8 0.1 2e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 EAQ87020.1 - 3.9e-11 42.7 0.0 0.00027 20.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ87020.1 - 7e-05 23.1 0.0 3.2 8.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Clr5 PF14420.1 EAQ87020.1 - 0.0002 21.1 0.2 0.27 11.1 0.0 2.7 2 0 0 2 2 2 2 Clr5 domain TPR_10 PF13374.1 EAQ87020.1 - 0.00087 19.1 0.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87020.1 - 0.014 15.0 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_4 PF07721.9 EAQ87020.1 - 0.026 14.9 0.8 0.5 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ87020.1 - 0.05 13.5 0.1 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87020.1 - 0.09 12.6 0.0 5.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PetN PF03742.9 EAQ87020.1 - 0.17 11.4 0.5 0.41 10.2 0.3 1.6 1 0 0 1 1 1 0 PetN Glyco_hydro_61 PF03443.9 EAQ87021.1 - 1.4e-54 185.1 1.0 1.6e-54 184.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4555 PF15093.1 EAQ87021.1 - 0.031 13.1 0.3 0.059 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4555) Glyco_hydro_61 PF03443.9 EAQ87022.1 - 2.6e-55 187.6 0.4 3e-55 187.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GMC_oxred_N PF00732.14 EAQ87023.1 - 3.9e-30 105.0 0.0 6.2e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAQ87023.1 - 4.9e-10 38.8 0.2 0.00016 20.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAQ87023.1 - 1.3e-09 37.5 0.2 1.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ87023.1 - 8.5e-06 25.7 0.0 2.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ87023.1 - 2e-05 24.5 1.7 2.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ87023.1 - 0.0014 18.7 0.0 0.068 13.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ87023.1 - 0.0026 16.2 0.0 0.0082 14.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EAQ87023.1 - 0.0031 16.6 0.1 0.0059 15.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EAQ87023.1 - 0.037 13.1 0.1 2 7.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAQ87023.1 - 0.045 12.6 0.1 0.071 12.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EAQ87023.1 - 0.092 13.1 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ87023.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Prenyltrans PF00432.16 EAQ87024.1 - 0.0099 15.4 0.2 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Pho88 PF10032.4 EAQ87025.1 - 1.7e-78 262.2 0.0 1.9e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.7 EAQ87026.1 - 2.7e-28 97.2 4.2 2.7e-28 97.2 2.9 2.3 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EAQ87026.1 - 0.029 14.0 4.9 0.063 12.9 3.4 1.6 1 0 0 1 1 1 0 XPA protein N-terminal zf-C3HC4_3 PF13920.1 EAQ87026.1 - 4.2 7.1 7.1 36 4.1 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 EAQ87027.1 - 4.6e-32 108.7 15.3 1.1e-06 28.2 0.0 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 EAQ87027.1 - 5e-27 94.8 5.4 5e-27 94.8 3.7 2.4 2 0 0 2 2 2 1 Striatin family Cytochrom_D1 PF02239.11 EAQ87027.1 - 0.11 10.8 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Asp PF00026.18 EAQ87028.1 - 9.6e-72 241.8 4.0 1.1e-69 235.1 2.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ87028.1 - 2.6e-09 37.2 0.3 3.7e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ87028.1 - 0.00019 21.8 1.2 0.17 12.3 0.3 2.9 2 1 0 2 2 2 2 Aspartyl protease PTR2 PF00854.16 EAQ87029.1 - 1.9e-24 86.1 0.1 7.1e-22 77.7 0.1 2.2 1 1 0 1 1 1 1 POT family RVT_1 PF00078.22 EAQ87030.1 - 1.1e-39 135.9 0.0 1.8e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ87030.1 - 1.4e-13 50.4 0.0 4.2e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ87030.1 - 4.3e-08 33.4 0.1 8e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S19 PF00203.16 EAQ87031.1 - 5.3e-20 70.8 0.0 9.5e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EAQ87032.1 - 2.6e-26 91.1 0.4 4e-26 90.5 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Mre11_DNA_bind PF04152.9 EAQ87033.1 - 6.9e-48 162.8 0.2 1.8e-47 161.4 0.1 1.8 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EAQ87033.1 - 1.4e-26 93.1 1.6 1.9e-26 92.7 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAQ87033.1 - 2.7e-05 24.0 0.0 6.5e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_60s PF00428.14 EAQ87033.1 - 1.8 9.0 12.7 6.8 7.1 8.8 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein APC10 PF03256.11 EAQ87034.1 - 2.1e-46 157.9 0.0 2.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.8 EAQ87034.1 - 0.017 14.9 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 PITH domain F5_F8_type_C PF00754.20 EAQ87034.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain Helitron_like_N PF14214.1 EAQ87035.1 - 1.2e-39 135.8 0.4 2.6e-39 134.8 0.3 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ87035.1 - 1.7e-31 109.4 0.0 2.1e-27 96.0 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase DDE_1 PF03184.14 EAQ87035.1 - 4.3e-27 94.6 0.0 9.1e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease MULE PF10551.4 EAQ87035.1 - 4.4e-12 45.9 0.0 1.2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain AAA_30 PF13604.1 EAQ87035.1 - 1.7e-06 27.7 0.0 2.2e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ87035.1 - 0.0041 16.8 0.1 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EAQ87035.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EAQ87035.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Torsin DDE_1 PF03184.14 EAQ87037.1 - 1.9e-29 102.3 0.0 1.1e-21 76.9 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ87037.1 - 1.8e-06 27.4 0.4 4.1e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ87037.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease WD40_alt PF14077.1 EAQ87037.1 - 0.078 12.6 0.4 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif AT_hook PF02178.14 EAQ87039.1 - 0.029 14.0 4.3 0.056 13.1 3.0 1.5 1 0 0 1 1 1 0 AT hook motif FAD-SLDH PF12318.3 EAQ87039.1 - 0.13 11.8 0.2 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase GP40 PF11025.3 EAQ87040.1 - 3.3 7.2 6.8 6.8 6.2 4.7 1.4 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DNA_pol_viral_N PF00242.12 EAQ87040.1 - 3.8 6.4 14.4 7 5.5 10.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF566 PF04484.7 EAQ87040.1 - 8.2 5.8 18.3 15 4.9 12.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Helicase_C PF00271.26 EAQ87041.1 - 3.2e-09 36.5 0.6 7.3e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ87041.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ87041.1 - 0.0042 16.9 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DDE_1 PF03184.14 EAQ87043.1 - 3e-32 111.5 0.0 1.2e-21 76.8 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ87043.1 - 2.2e-06 27.0 0.4 4.7e-06 26.0 0.3 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ87043.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease WD40_alt PF14077.1 EAQ87043.1 - 0.098 12.3 0.4 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif FKBP_N PF01346.13 EAQ87044.1 - 0.012 15.6 1.4 0.025 14.6 0.5 1.8 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Remorin_C PF03763.8 EAQ87044.1 - 0.017 14.6 0.6 0.032 13.7 0.4 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region RRM_6 PF14259.1 EAQ87044.1 - 0.045 13.7 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PB1 PF00564.19 EAQ87044.1 - 0.12 12.0 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 PB1 domain Herpes_UL25 PF01499.11 EAQ87044.1 - 0.13 10.5 0.2 0.18 10.0 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family RVT_1 PF00078.22 EAQ87046.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_30 PF02055.11 EAQ87047.1 - 7.5e-18 63.9 1.7 8.5e-13 47.3 0.7 2.6 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EAQ87047.1 - 8.8e-15 54.5 0.2 5.2e-14 51.9 0.1 2.0 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha_GJ PF03229.8 EAQ87048.1 - 0.027 14.8 2.6 0.068 13.5 1.8 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF244 PF03112.9 EAQ87050.1 - 0.14 11.6 1.1 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF FUSC PF04632.7 EAQ87050.1 - 8.3 4.6 13.8 25 3.1 9.6 1.8 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 EAQ87050.1 - 9.5 6.6 10.3 0.89 9.9 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DDE_1 PF03184.14 EAQ87051.1 - 1.4e-42 145.3 0.0 2.3e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ87051.1 - 1.9e-12 46.5 0.0 3.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ87051.1 - 3e-09 36.5 0.0 1.3e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ87051.1 - 0.031 14.2 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 Stage III sporulation protein D DUF904 PF06005.7 EAQ87051.1 - 0.1 12.8 1.9 0.23 11.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) BC10 PF06726.7 EAQ87052.1 - 2.3e-16 59.5 12.1 3.8e-16 58.8 8.4 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 KfrA_N PF11740.3 EAQ87052.1 - 0.17 12.3 1.8 0.23 11.9 1.2 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Y_phosphatase PF00102.22 EAQ87053.1 - 1.9e-55 187.7 0.0 2.5e-31 108.8 0.0 4.2 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EAQ87053.1 - 1.4e-12 47.9 0.0 3.8e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EAQ87053.1 - 0.02 15.1 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EAQ87053.1 - 0.16 11.5 0.2 0.39 10.3 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.24 EAQ87054.1 - 2.3e-44 150.8 0.0 3.7e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ87054.1 - 1.3e-08 34.6 0.0 3.4e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EAQ87054.1 - 5.7e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EAQ87054.1 - 1.4e-06 28.3 0.0 2.8e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ87054.1 - 1.7e-06 28.1 0.1 0.00012 22.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ87054.1 - 3.6e-05 24.5 0.1 7.1e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAQ87054.1 - 4e-05 22.7 0.0 7.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ87054.1 - 9.3e-05 22.1 0.1 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAQ87054.1 - 0.00026 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EAQ87054.1 - 0.00051 18.8 0.0 0.00094 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EAQ87054.1 - 0.00084 19.2 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ87054.1 - 0.0009 19.1 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EAQ87054.1 - 0.0012 18.4 0.0 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EAQ87054.1 - 0.0014 17.7 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EAQ87054.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAQ87054.1 - 0.0041 16.2 0.0 0.0092 15.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EAQ87054.1 - 0.0042 16.2 0.0 0.0096 15.0 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EAQ87054.1 - 0.0044 17.3 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EAQ87054.1 - 0.0082 15.6 0.0 0.049 13.1 0.0 2.2 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_25 PF13481.1 EAQ87054.1 - 0.0089 15.4 0.1 0.049 13.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 EAQ87054.1 - 0.011 14.9 0.0 0.043 13.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EAQ87054.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAQ87054.1 - 0.016 14.1 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EAQ87054.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EAQ87054.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Histone PF00125.19 EAQ87054.1 - 0.031 14.4 0.1 0.086 12.9 0.0 1.8 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 Parvo_NS1 PF01057.12 EAQ87054.1 - 0.032 13.0 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EAQ87054.1 - 0.044 13.4 0.0 0.34 10.5 0.0 2.0 1 1 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EAQ87054.1 - 0.053 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EAQ87054.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Na_Ca_ex PF01699.19 EAQ87055.1 - 2.4e-33 114.6 22.3 1.1e-19 70.3 6.0 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EAQ87055.1 - 2.9e-13 50.0 13.3 2.9e-13 50.0 9.2 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DUF1996 PF09362.5 EAQ87056.1 - 5.3e-78 261.9 1.1 6.8e-78 261.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HIPIP PF01355.12 EAQ87056.1 - 4.9 7.3 6.6 7 6.8 0.0 3.0 3 0 0 3 3 3 0 High potential iron-sulfur protein Inositol_P PF00459.20 EAQ87058.1 - 6.7e-36 123.9 0.0 1.8e-35 122.5 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family R3H PF01424.17 EAQ87059.1 - 2e-10 40.2 0.1 4.1e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 EAQ87059.1 - 5.1e-08 32.4 0.0 8.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ87059.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ87059.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EAQ87059.1 - 0.057 13.4 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Histone PF00125.19 EAQ87061.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAQ87061.1 - 4.3e-05 23.4 0.0 6.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F-box PF00646.28 EAQ87063.1 - 2.3e-09 36.6 0.5 4.9e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAQ87063.1 - 5.3e-07 29.2 0.6 5.3e-07 29.2 0.4 1.8 2 0 0 2 2 2 1 F-box-like HD PF01966.17 EAQ87064.1 - 0.00049 20.1 0.2 0.00071 19.5 0.2 1.3 1 0 0 1 1 1 1 HD domain Imm28 PF15574.1 EAQ87064.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 28 MULE PF10551.4 EAQ87065.1 - 1.9e-12 47.2 0.1 5e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ87065.1 - 0.00083 19.8 0.3 0.0022 18.4 0.2 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain RdRP PF05183.7 EAQ87066.1 - 7.8e-136 454.1 0.1 9.9e-101 338.2 0.0 2.2 1 1 1 2 2 2 2 RNA dependent RNA polymerase Josephin PF02099.12 EAQ87066.1 - 0.11 12.1 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Josephin RRM_6 PF14259.1 EAQ87066.1 - 0.12 12.3 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Meth_synt_2 PF01717.13 EAQ87067.1 - 8.6e-10 38.0 0.0 1.8e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EAQ87067.1 - 0.00043 19.6 0.0 0.002 17.4 0.0 2.1 2 1 1 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Abhydrolase_6 PF12697.2 EAQ87068.1 - 1.2e-25 90.7 0.6 7.5e-25 88.1 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87068.1 - 7.8e-08 32.1 0.0 4.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ87068.1 - 2.4e-05 24.1 0.0 6.4e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 EAQ87068.1 - 0.00011 23.1 0.2 0.089 13.7 0.1 2.8 2 0 0 2 2 2 2 EthD domain Ndr PF03096.9 EAQ87068.1 - 0.00046 18.7 0.0 0.0011 17.5 0.0 1.6 1 1 0 1 1 1 1 Ndr family DUF4286 PF14114.1 EAQ87068.1 - 0.012 15.8 0.1 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Esterase PF00756.15 EAQ87068.1 - 0.023 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chitin_bind_3 PF03067.10 EAQ87069.1 - 6.3e-08 33.0 0.2 8.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Chitin binding domain DUF1883 PF08980.5 EAQ87069.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) DUF2985 PF11204.3 EAQ87071.1 - 1.6e-25 88.6 2.6 3.3e-25 87.6 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF1296 PF06972.6 EAQ87071.1 - 4.7 7.2 7.2 0.44 10.5 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) RCR PF12273.3 EAQ87071.1 - 8.8 6.8 12.9 2.9 8.4 0.3 3.3 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red zf-GRF PF06839.7 EAQ87072.1 - 0.035 14.0 0.3 0.077 12.9 0.2 1.6 1 0 0 1 1 1 0 GRF zinc finger EspF PF04806.7 EAQ87072.1 - 0.068 13.3 0.2 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 EspF protein repeat Phage_Nu1 PF07471.7 EAQ87072.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 FAR1 PF03101.10 EAQ87072.1 - 0.15 12.5 3.8 0.22 12.0 2.6 1.2 1 0 0 1 1 1 0 FAR1 DNA-binding domain RVT_1 PF00078.22 EAQ87073.1 - 1.3e-39 135.8 0.0 2e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 EAQ87073.1 - 6.6e-37 127.0 49.2 6.6e-37 127.0 34.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ87073.1 - 2.5e-17 62.3 16.9 3.9e-17 61.6 11.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Exo_endo_phos_2 PF14529.1 EAQ87073.1 - 5.4e-13 48.6 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ87073.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PolyG_pol PF01518.11 EAQ87073.1 - 0.053 11.9 0.5 0.087 11.2 0.3 1.2 1 0 0 1 1 1 0 Sigma NS protein AA_permease_2 PF13520.1 EAQ87074.1 - 7.4e-74 248.7 16.1 8.2e-74 248.6 11.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAQ87074.1 - 6.9e-15 54.3 15.8 9.4e-15 53.9 10.9 1.0 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EAQ87074.1 - 2.1 6.7 11.7 2.2 6.6 7.5 1.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein RVT_1 PF00078.22 EAQ87075.1 - 4.5e-27 94.8 0.0 9.4e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.9 EAQ87075.1 - 7.5e-14 51.1 0.0 1.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PI-PLC-X PF00388.14 EAQ87076.1 - 3.5e-48 162.7 0.0 5.1e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAQ87076.1 - 1.5e-29 102.3 0.1 3.6e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain Glyco_hydro_7 PF00840.15 EAQ87077.1 - 2.7e-187 622.4 16.3 3.2e-187 622.1 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.3 EAQ87077.1 - 0.0068 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3764) Dimer_Tnp_hAT PF05699.9 EAQ87078.1 - 6.9e-17 60.8 0.0 1.9e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pyr_redox_2 PF07992.9 EAQ87079.1 - 2.1e-18 66.9 0.0 1.1e-16 61.3 0.0 3.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ87079.1 - 1.7e-10 41.1 0.2 1.8e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ87079.1 - 5.5e-06 25.5 0.2 0.017 14.0 0.0 3.4 3 1 1 4 4 4 2 Lycopene cyclase protein Trp_halogenase PF04820.9 EAQ87079.1 - 9.4e-06 24.5 1.0 1 7.9 0.0 3.2 2 1 1 3 3 3 3 Tryptophan halogenase Pyr_redox_3 PF13738.1 EAQ87079.1 - 5.7e-05 23.2 0.1 0.028 14.5 0.0 3.3 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ87079.1 - 0.0017 18.1 0.4 22 4.7 0.0 4.3 4 1 1 5 5 5 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EAQ87079.1 - 0.0044 15.9 0.2 0.019 13.9 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EAQ87079.1 - 0.021 13.7 0.3 6 5.5 0.0 3.0 3 0 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.2 EAQ87079.1 - 0.079 12.0 1.9 26 3.7 0.3 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ87079.1 - 0.12 12.4 0.2 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAQ87079.1 - 0.18 10.2 1.4 1.4 7.2 0.0 2.9 5 0 0 5 5 5 0 HI0933-like protein UPRTase PF14681.1 EAQ87080.1 - 3.2e-37 127.7 0.1 9.5e-37 126.2 0.1 1.8 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.2 EAQ87080.1 - 1.3e-08 35.2 0.0 2.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EAQ87080.1 - 9.7e-06 26.4 0.0 3.9e-05 24.4 0.0 2.0 1 1 1 2 2 1 1 AAA domain AAA_18 PF13238.1 EAQ87080.1 - 1.3e-05 25.4 0.0 0.00032 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EAQ87080.1 - 0.00013 21.1 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Pribosyltran PF00156.22 EAQ87080.1 - 0.00013 21.6 1.3 0.0092 15.7 0.9 2.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain ArgK PF03308.11 EAQ87080.1 - 0.00074 18.3 0.0 0.0021 16.8 0.0 1.7 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EAQ87080.1 - 0.0014 18.6 1.1 0.0094 15.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain HAD_2 PF13419.1 EAQ87080.1 - 0.0016 18.6 0.2 0.0055 16.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_33 PF13671.1 EAQ87080.1 - 0.0016 18.2 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAQ87080.1 - 0.012 14.7 0.1 0.032 13.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EAQ87080.1 - 0.021 14.5 0.0 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EAQ87080.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EAQ87080.1 - 0.041 13.2 0.0 0.16 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ87080.1 - 0.044 12.6 0.1 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 EAQ87080.1 - 0.057 12.8 0.1 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EAQ87080.1 - 0.059 13.5 0.2 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EAQ87080.1 - 0.068 12.5 0.1 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase MMR_HSR1 PF01926.18 EAQ87080.1 - 0.086 12.8 0.0 0.34 10.8 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EAQ87080.1 - 0.19 11.6 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AA_permease_2 PF13520.1 EAQ87081.1 - 7.1e-34 117.0 49.8 4.6e-28 97.9 21.3 2.1 1 1 1 2 2 2 2 Amino acid permease DUF3505 PF12013.3 EAQ87081.1 - 1.3e-17 64.0 2.0 2.5e-08 34.1 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3505) AA_permease PF00324.16 EAQ87081.1 - 2.8e-17 62.2 50.9 6.1e-14 51.2 18.9 2.1 1 1 1 2 2 2 2 Amino acid permease zf-C2H2_2 PF12756.2 EAQ87081.1 - 0.2 11.7 0.5 29 4.8 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EAQ87081.1 - 0.51 10.6 8.0 0.4 11.0 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2207 PF09972.4 EAQ87081.1 - 2.4 6.6 0.0 9.4 4.6 0.0 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3505 PF12013.3 EAQ87082.1 - 1.4e-14 54.1 0.8 1.7e-14 53.9 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-Di19 PF05605.7 EAQ87082.1 - 0.32 11.1 5.6 1.9 8.6 0.5 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EAQ87082.1 - 1.3 9.1 4.0 5.9 7.0 2.8 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GspH PF12019.3 EAQ87084.1 - 1.2e-07 31.8 14.5 5.7 7.1 0.0 8.3 1 1 4 6 6 6 5 Type II transport protein GspH Colicin_Pyocin PF01320.13 EAQ87084.1 - 3.2 7.6 6.8 1.4e+02 2.4 0.0 6.2 8 3 3 11 11 11 0 Colicin immunity protein / pyocin immunity protein FTA2 PF13095.1 EAQ87085.1 - 2.4e-30 105.6 0.0 3.1e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sigma70_r1_2 PF00140.15 EAQ87085.1 - 0.048 13.3 0.1 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Glyco_hydro_3 PF00933.16 EAQ87087.1 - 3.3e-65 220.0 0.0 4.3e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ87087.1 - 8.3e-60 202.1 0.1 1.3e-59 201.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ87087.1 - 2.2e-23 81.9 0.1 6.4e-23 80.4 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.8 EAQ87087.1 - 0.049 12.5 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_31 PF01055.21 EAQ87088.1 - 4.5e-115 384.9 0.2 5.4e-115 384.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAQ87088.1 - 7.3e-18 64.2 0.2 3.8e-17 61.8 0.0 2.4 3 0 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 EAQ87089.1 - 1.1e-97 327.5 24.7 1.2e-97 327.3 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ87089.1 - 2.3e-24 85.8 55.0 2.6e-23 82.2 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAQ87089.1 - 6.6e-06 24.6 1.1 6.6e-06 24.6 0.7 1.8 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EAQ87089.1 - 0.0002 20.1 0.9 0.0002 20.1 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Cutinase PF01083.17 EAQ87090.1 - 5.7e-25 88.0 0.0 7.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EAQ87090.1 - 0.0014 18.3 0.0 0.0014 18.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EAQ87090.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 EAQ87090.1 - 0.031 14.1 0.1 0.036 13.9 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87090.1 - 0.056 12.9 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.6 EAQ87090.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.3 EAQ87090.1 - 0.095 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1399 PF07173.7 EAQ87091.1 - 2.6e-17 63.3 11.4 7.8e-15 55.3 0.1 4.2 4 1 1 5 5 5 3 Protein of unknown function (DUF1399) Ubiquitin_3 PF14836.1 EAQ87091.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Sporozoite_P67 PF05642.6 EAQ87091.1 - 0.18 9.6 2.2 0.24 9.2 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF605 PF04652.11 EAQ87092.1 - 0.0048 16.3 28.5 0.008 15.6 19.8 1.3 1 0 0 1 1 1 1 Vta1 like E1-E2_ATPase PF00122.15 EAQ87093.1 - 4e-62 209.2 1.9 4e-62 209.2 1.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ87093.1 - 2.6e-28 99.9 0.0 4.1e-27 96.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EAQ87093.1 - 8.1e-23 80.8 13.4 1.5e-22 79.9 5.0 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EAQ87093.1 - 4.1e-18 65.1 0.0 1.2e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAQ87093.1 - 7.5e-16 57.3 0.1 2e-15 56.0 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAQ87093.1 - 3.1e-11 43.8 0.0 9.6e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ87093.1 - 0.0019 17.8 0.4 0.0032 17.0 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GMC_oxred_C PF05199.8 EAQ87094.1 - 1.6e-14 54.4 0.1 1.6e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase zf-RVT PF13966.1 EAQ87095.1 - 0.049 13.9 1.9 0.06 13.6 0.2 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase RVT_3 PF13456.1 EAQ87095.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Helitron_like_N PF14214.1 EAQ87096.1 - 9.5e-42 142.8 0.5 2.2e-41 141.6 0.4 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus CVNH PF08881.5 EAQ87096.1 - 5.8e-32 110.0 0.2 1e-31 109.2 0.1 1.4 1 0 0 1 1 1 1 CVNH domain PIF1 PF05970.9 EAQ87096.1 - 9.2e-26 90.6 0.0 1.1e-21 77.2 0.0 2.3 2 1 0 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ87096.1 - 1.3e-05 23.1 0.0 3e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EAQ87096.1 - 2.4e-05 24.4 0.0 8.6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EAQ87096.1 - 0.00019 21.1 0.0 0.00076 19.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ87096.1 - 0.0025 17.5 0.3 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EAQ87096.1 - 0.13 11.8 0.0 15 4.9 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rtt106 PF08512.7 EAQ87097.1 - 1.6e-24 85.6 0.0 6.6e-24 83.7 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like zf-C2H2_4 PF13894.1 EAQ87098.1 - 0.001 19.2 18.3 1.4 9.4 0.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ87098.1 - 0.012 15.9 21.0 0.14 12.5 0.3 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EAQ87098.1 - 7.4 6.8 10.2 3.9 7.7 0.7 3.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 EAQ87099.1 - 1.5e-18 66.7 0.1 4.6e-10 39.1 0.1 3.0 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAQ87099.1 - 0.0037 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EAQ87099.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EAQ87099.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Vfa1 PF08432.5 EAQ87100.1 - 9.7e-41 139.7 13.9 1.2e-40 139.5 9.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.8 EAQ87100.1 - 0.48 8.8 7.1 0.62 8.5 4.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 EAQ87100.1 - 0.65 7.6 9.9 0.8 7.3 6.8 1.0 1 0 0 1 1 1 0 Ycf1 GCD14 PF08704.5 EAQ87100.1 - 0.68 9.3 2.9 0.87 9.0 2.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Pox_Ag35 PF03286.9 EAQ87100.1 - 0.69 9.3 16.2 1 8.8 11.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EAQ87100.1 - 0.79 7.6 10.6 0.93 7.4 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.7 EAQ87100.1 - 1.1 8.7 21.2 1.6 8.2 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) APC_CDC26 PF10471.4 EAQ87100.1 - 1.2 9.9 10.8 2.3 9.0 7.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF4407 PF14362.1 EAQ87100.1 - 1.9 7.3 4.3 2.3 7.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 EAQ87100.1 - 2.2 8.1 10.3 2.8 7.7 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Selenoprotein_S PF06936.6 EAQ87100.1 - 2.2 7.7 7.9 3.4 7.1 5.4 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) BTV_NS2 PF04514.7 EAQ87100.1 - 2.6 6.8 12.0 3.2 6.5 8.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dicty_REP PF05086.7 EAQ87100.1 - 3 5.4 8.8 3.8 5.1 6.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1510 PF07423.6 EAQ87100.1 - 3.1 7.1 19.1 3.9 6.7 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4337 PF14235.1 EAQ87100.1 - 3.6 7.3 8.1 5.5 6.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spc24 PF08286.6 EAQ87100.1 - 4.1 7.1 10.4 7.2 6.3 7.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6 PF04111.7 EAQ87100.1 - 5 6.0 11.3 7.4 5.5 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CobT PF06213.7 EAQ87100.1 - 5.4 6.0 14.9 7.3 5.6 10.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RP-C_C PF11800.3 EAQ87100.1 - 8 6.1 7.6 11 5.6 5.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Paf1 PF03985.8 EAQ87100.1 - 9 4.9 17.5 12 4.5 12.2 1.1 1 0 0 1 1 1 0 Paf1 U79_P34 PF03064.11 EAQ87100.1 - 9.4 5.6 16.4 13 5.2 11.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_2 PF07719.12 EAQ87101.1 - 4.3e-07 29.3 9.2 0.022 14.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87101.1 - 1.9e-05 24.2 5.7 0.013 15.1 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 EAQ87101.1 - 0.00081 20.0 22.2 0.27 11.9 1.4 6.0 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ87101.1 - 0.0013 18.6 7.5 0.13 12.1 0.3 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ87101.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ87101.1 - 0.19 11.6 1.9 12 5.8 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ87101.1 - 0.3 10.7 5.4 22 4.8 0.2 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ87101.1 - 0.37 11.3 9.1 0.86 10.2 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ87101.1 - 3.6 8.4 11.0 27 5.7 0.3 5.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EAQ87103.1 - 4.1e-116 388.2 20.0 4.6e-116 388.0 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ87103.1 - 2.2e-21 75.9 34.3 7.2e-21 74.2 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 EAQ87103.1 - 0.028 14.7 0.1 0.056 13.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat GDPD PF03009.12 EAQ87104.1 - 1.2e-15 57.7 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SET PF00856.23 EAQ87105.1 - 4.2e-09 36.9 0.1 8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 SET domain IPT PF01745.11 EAQ87105.1 - 0.0045 16.1 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase TPR_12 PF13424.1 EAQ87105.1 - 0.025 14.5 0.1 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 EAQ87106.1 - 4.8e-19 68.1 6.8 1.2e-18 66.9 0.7 3.2 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 EAQ87106.1 - 3.3e-12 46.1 0.1 6.2e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like SH3_3 PF08239.6 EAQ87107.1 - 0.063 13.4 0.1 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain RVT_1 PF00078.22 EAQ87108.1 - 9.3e-31 106.8 0.0 1.5e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ87108.1 - 3.4e-21 75.0 0.0 6.6e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ87108.1 - 1.3e-09 38.3 0.0 3.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EAQ87108.1 - 0.00017 21.3 3.7 0.00038 20.2 2.5 1.7 1 0 0 1 1 1 1 Zinc knuckle PurS PF02700.9 EAQ87108.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase GST_N_2 PF13409.1 EAQ87109.1 - 2.6e-13 49.7 0.0 2.1e-12 46.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ87109.1 - 2.8e-13 49.9 0.0 7.6e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAQ87109.1 - 4.2e-13 49.2 0.0 9.3e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAQ87109.1 - 8.7e-12 44.7 0.0 1.7e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ87109.1 - 2.8e-10 40.0 0.0 6.9e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ87109.1 - 3.3e-08 33.9 0.1 5.7e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.8 EAQ87110.1 - 0.0021 17.3 0.0 0.0053 16.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family DCA16 PF15349.1 EAQ87110.1 - 0.042 13.2 0.1 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Pyridox_oxidase PF01243.15 EAQ87111.1 - 5.7e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 EAQ87112.1 - 1.5e-16 60.7 0.2 1.9e-16 60.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ87112.1 - 1.1e-07 31.7 0.3 1.4e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ87112.1 - 1.6e-07 31.3 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2263 PF10021.4 EAQ87113.1 - 9e-21 74.4 0.1 5.9e-20 71.7 0.1 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) APH PF01636.18 EAQ87114.1 - 3.1e-29 102.3 0.0 6.7e-29 101.3 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 EAQ87115.1 - 4.9e-37 127.5 0.0 6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA PF00004.24 EAQ87116.1 - 2.4e-15 56.8 0.0 4.1e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ87116.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ87116.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NOA36 PF06524.7 EAQ87116.1 - 0.23 10.6 0.4 0.32 10.2 0.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2781 PF10914.3 EAQ87118.1 - 4.3e-38 130.4 9.8 4.9e-38 130.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Glyco_hydro_cc PF11790.3 EAQ87120.1 - 4.5e-63 212.8 0.1 5.4e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Abhydrolase_6 PF12697.2 EAQ87121.1 - 5.9e-06 26.3 2.3 1.3e-05 25.2 1.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EAQ87121.1 - 7.4e-05 22.2 0.3 0.00022 20.7 0.1 1.9 1 1 1 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.2 EAQ87121.1 - 0.007 16.1 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ87121.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rad60-SLD_2 PF13881.1 EAQ87121.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PLDc_N PF13396.1 EAQ87123.1 - 1e-13 50.6 3.4 1.6e-13 50.1 2.4 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal Pox_A14 PF05767.7 EAQ87123.1 - 0.026 14.4 0.3 0.037 13.9 0.2 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3976 PF13121.1 EAQ87123.1 - 0.043 13.6 1.4 0.043 13.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) Glucos_trans_II PF14264.1 EAQ87123.1 - 0.06 12.3 4.7 0.038 12.9 2.4 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII NfeD PF01957.13 EAQ87123.1 - 0.082 13.0 1.7 0.09 12.9 0.7 1.3 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF3951 PF13131.1 EAQ87123.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF3671 PF12420.3 EAQ87123.1 - 0.19 11.7 0.7 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function UPF0104 PF03706.8 EAQ87123.1 - 0.21 10.8 5.3 0.55 9.4 3.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) Cation_ATPase_C PF00689.16 EAQ87123.1 - 0.79 9.2 4.8 1 8.8 3.3 1.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4199 PF13858.1 EAQ87123.1 - 0.91 9.4 5.1 0.13 12.1 1.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2304 PF10066.4 EAQ87123.1 - 1.5 8.6 4.5 0.39 10.5 1.2 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) MULE PF10551.4 EAQ87124.1 - 0.0028 17.7 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain RVT_1 PF00078.22 EAQ87125.1 - 3.3e-28 98.4 0.0 8e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ87125.1 - 1.6e-20 72.8 0.0 9e-20 70.4 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ87125.1 - 5.1e-09 36.4 0.1 1.3e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IncA PF04156.9 EAQ87125.1 - 0.022 14.3 1.3 0.056 13.0 0.9 1.7 1 0 0 1 1 1 0 IncA protein Herpes_UL6 PF01763.11 EAQ87125.1 - 0.058 11.5 1.0 0.15 10.2 0.7 1.6 1 0 0 1 1 1 0 Herpesvirus UL6 like ApoLp-III PF07464.6 EAQ87125.1 - 0.24 11.3 3.3 8.1 6.4 0.9 3.1 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CASP_C PF08172.7 EAQ87125.1 - 0.27 10.2 7.9 0.42 9.5 2.0 2.6 2 0 0 2 2 2 0 CASP C terminal DUF342 PF03961.8 EAQ87125.1 - 0.29 9.4 0.6 0.49 8.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 EAQ87125.1 - 0.71 10.2 7.3 1.6 9.1 4.4 2.2 1 1 0 1 1 1 0 SlyX DUF883 PF05957.8 EAQ87125.1 - 5.8 7.3 14.0 2.1 8.7 0.2 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FTA2 PF13095.1 EAQ87126.1 - 1e-29 103.6 0.0 1.3e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sigma70_r1_2 PF00140.15 EAQ87126.1 - 0.051 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 EB PF01683.13 EAQ87127.1 - 0.001 19.0 27.5 0.22 11.5 2.0 3.4 3 0 0 3 3 3 3 EB module DUF1034 PF06280.7 EAQ87127.1 - 0.84 10.0 2.7 31 5.0 1.9 2.3 1 1 0 1 1 1 0 Fn3-like domain (DUF1034) Cytadhesin_P30 PF07271.6 EAQ87127.1 - 3.9 6.6 9.5 5.7 6.1 6.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 FYVE PF01363.16 EAQ87128.1 - 2.4 8.1 7.5 3.2 7.7 4.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger Bacillus_HBL PF05791.6 EAQ87129.1 - 0.038 13.3 2.3 0.067 12.5 1.6 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) LMWPc PF01451.16 EAQ87129.1 - 0.094 13.0 0.0 3.1 8.1 0.0 2.5 2 1 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF972 PF06156.8 EAQ87129.1 - 0.87 9.9 3.4 1.2 9.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kinesin PF00225.18 EAQ87131.1 - 2.9e-46 157.7 0.0 8.6e-46 156.1 0.0 1.8 1 1 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 EAQ87131.1 - 0.0052 16.4 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 EAQ87131.1 - 0.64 9.8 5.1 4.6 7.0 0.9 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Jnk-SapK_ap_N PF09744.4 EAQ87131.1 - 0.84 9.6 8.1 0.074 13.0 2.2 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Ank_2 PF12796.2 EAQ87133.1 - 1.7e-47 159.6 0.0 1e-11 44.9 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ87133.1 - 3.3e-38 129.3 0.6 1.5e-08 34.9 0.0 5.8 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ87133.1 - 1.4e-36 123.6 4.0 8e-08 32.2 0.0 6.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EAQ87133.1 - 1.6e-36 122.2 1.4 1.8e-06 27.4 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EAQ87133.1 - 8e-27 90.6 0.0 0.0022 18.0 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat NACHT PF05729.7 EAQ87133.1 - 5.1e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ87133.1 - 5.2e-05 23.3 0.1 0.00065 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAQ87133.1 - 0.00079 18.3 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EAQ87133.1 - 0.0093 16.1 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EAQ87133.1 - 0.3 10.0 0.0 0.85 8.5 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain PrpR_N PF06506.6 EAQ87135.1 - 0.021 14.2 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator CMD PF02627.15 EAQ87135.1 - 0.027 14.3 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Methyltransf_11 PF08241.7 EAQ87136.1 - 3.6e-14 53.0 0.0 9.6e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ87136.1 - 1.3e-11 44.7 0.0 2.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ87136.1 - 8.1e-11 41.7 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ87136.1 - 2.4e-09 37.0 0.0 6.9e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ87136.1 - 5.6e-09 36.5 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ87136.1 - 5.3e-08 33.1 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ87136.1 - 3.3e-07 30.3 0.8 1.2e-06 28.4 0.5 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EAQ87136.1 - 0.022 13.4 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EAQ87136.1 - 0.046 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NmrA PF05368.8 EAQ87137.1 - 2.2e-19 69.6 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ87137.1 - 2.9e-09 37.1 0.1 4.6e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ87137.1 - 0.0093 15.4 0.1 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EAQ87137.1 - 0.028 14.6 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DCX PF03607.12 EAQ87137.1 - 0.042 13.4 0.1 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Doublecortin ApbA PF02558.11 EAQ87137.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MurB_C PF02873.11 EAQ87138.1 - 0.011 15.5 0.1 1.6 8.5 0.1 2.3 1 1 1 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SNF2_N PF00176.18 EAQ87139.1 - 7.1e-51 172.7 0.0 1.1e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain NB-ARC PF00931.17 EAQ87140.1 - 0.00013 20.9 0.0 0.00026 19.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_11 PF13086.1 EAQ87140.1 - 0.0031 17.1 0.0 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ87140.1 - 0.0033 17.4 0.0 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EAQ87140.1 - 0.0034 17.0 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain DAP3 PF10236.4 EAQ87140.1 - 0.039 12.8 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 KAP_NTPase PF07693.9 EAQ87140.1 - 0.044 12.7 0.1 2.8 6.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 EAQ87140.1 - 0.046 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EAQ87140.1 - 0.073 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HET PF06985.6 EAQ87141.1 - 4.5e-38 130.5 1.3 6.9e-38 129.9 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tannase PF07519.6 EAQ87142.1 - 1.4e-82 277.9 0.0 2.4e-82 277.1 0.0 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EAQ87142.1 - 7.8e-08 32.4 0.1 2.6e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87142.1 - 0.00076 19.2 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ87142.1 - 0.00086 18.5 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EAQ87142.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kei1 PF08552.6 EAQ87144.1 - 1.2e-57 194.6 2.0 1.4e-57 194.4 1.4 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.17 EAQ87145.1 - 1.2e-55 187.1 0.1 1.4e-47 160.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EAQ87145.1 - 1.5e-32 111.0 0.0 1.2e-16 60.0 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EAQ87145.1 - 4.9e-29 101.1 0.0 1.2e-28 99.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EAQ87145.1 - 2.6e-08 33.6 0.0 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Chitin_synth_1 PF01644.12 EAQ87146.1 - 5.5e-73 244.1 0.1 7.1e-73 243.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EAQ87146.1 - 0.0042 15.5 0.0 0.0087 14.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase MARVEL PF01284.18 EAQ87147.1 - 2.3e-27 95.6 1.5 2.7e-27 95.3 1.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Amastin PF07344.6 EAQ87147.1 - 0.13 11.8 1.4 0.25 10.9 0.9 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF202 PF02656.10 EAQ87147.1 - 3 8.1 7.1 47 4.2 3.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF1077 PF06417.7 EAQ87148.1 - 2.2e-11 43.1 3.1 3.1e-10 39.4 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1077) Adaptin_N PF01602.15 EAQ87149.1 - 1.4e-135 452.6 5.9 1.8e-135 452.2 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EAQ87149.1 - 8.2e-19 68.1 0.9 4.3e-18 65.7 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAQ87149.1 - 5.5e-17 61.8 4.4 1.6e-10 41.1 0.1 4.7 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EAQ87149.1 - 9.7e-13 47.0 1.4 6.9e-05 22.6 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EAQ87149.1 - 2.2e-06 27.9 2.9 0.044 14.2 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EAQ87149.1 - 1.8e-05 24.2 1.7 0.019 14.3 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal Arm PF00514.18 EAQ87149.1 - 0.00076 19.2 0.8 3.7 7.5 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EAQ87149.1 - 0.0013 18.4 0.1 0.13 12.0 0.0 3.6 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF2435 PF10363.4 EAQ87149.1 - 0.018 14.9 1.0 0.3 11.0 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) DNA_alkylation PF08713.6 EAQ87149.1 - 0.081 12.4 0.0 3.2 7.1 0.0 3.1 2 2 1 3 3 3 0 DNA alkylation repair enzyme GCR1_C PF12550.3 EAQ87150.1 - 2.6e-23 81.6 0.6 5.3e-23 80.6 0.4 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes F5_F8_type_C PF00754.20 EAQ87150.1 - 0.049 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain AAA PF00004.24 EAQ87151.1 - 2.6e-13 50.3 0.0 3.6e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ87151.1 - 3e-05 24.1 0.0 0.0013 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ87151.1 - 9.7e-05 22.4 0.2 0.00049 20.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain CPT PF07931.7 EAQ87151.1 - 0.00033 20.3 0.0 0.001 18.7 0.0 1.7 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EAQ87151.1 - 0.00089 20.0 0.0 0.0011 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAQ87151.1 - 0.0021 17.7 0.0 0.0054 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAQ87151.1 - 0.0031 16.5 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ87151.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EAQ87151.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ87151.1 - 0.021 15.1 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EAQ87151.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EAQ87151.1 - 0.042 13.4 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAQ87151.1 - 0.051 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Torsin PF06309.6 EAQ87151.1 - 0.057 13.2 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_3 PF07726.6 EAQ87151.1 - 0.092 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EAQ87151.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EAQ87151.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EAQ87151.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 EAQ87154.1 - 5e-41 140.8 0.0 1.3e-26 93.4 0.0 2.7 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EAQ87154.1 - 9.7e-18 64.4 0.0 4.5e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ87154.1 - 2.7e-08 33.4 0.3 6.8e-08 32.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EAQ87154.1 - 5.6e-05 22.9 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 NTPase ArgK PF03308.11 EAQ87154.1 - 0.0021 16.8 0.1 0.0035 16.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EAQ87154.1 - 0.0031 17.5 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EAQ87154.1 - 0.0045 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_11 PF13086.1 EAQ87154.1 - 0.0082 15.7 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ87154.1 - 0.0089 16.1 0.1 0.026 14.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAQ87154.1 - 0.014 14.8 0.1 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EAQ87154.1 - 0.016 15.1 0.0 0.057 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ87154.1 - 0.022 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAQ87154.1 - 0.035 13.8 0.2 0.089 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EAQ87154.1 - 0.072 13.3 0.1 0.36 11.0 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EAQ87154.1 - 0.079 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Helicase_RecD PF05127.9 EAQ87154.1 - 0.1 12.2 2.4 0.15 11.7 0.5 2.1 2 1 0 2 2 2 0 Helicase PIF1 PF05970.9 EAQ87155.1 - 8.7e-40 136.7 0.0 1.1e-24 87.0 0.0 2.6 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EAQ87155.1 - 7.3e-18 64.8 0.0 6.6e-17 61.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ87155.1 - 2.2e-07 30.5 0.1 7.2e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EAQ87155.1 - 0.00034 20.3 0.1 0.076 12.7 0.0 2.6 2 0 0 2 2 2 1 NTPase ArgK PF03308.11 EAQ87155.1 - 0.00087 18.1 0.5 0.0026 16.5 0.0 1.8 2 0 0 2 2 2 1 ArgK protein RNase_H PF00075.19 EAQ87155.1 - 0.0026 18.1 0.1 0.0078 16.5 0.0 1.8 1 0 0 1 1 1 1 RNase H AAA_16 PF13191.1 EAQ87155.1 - 0.003 17.5 1.1 0.086 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EAQ87155.1 - 0.0052 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAQ87155.1 - 0.0077 15.7 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_11 PF13086.1 EAQ87155.1 - 0.0099 15.4 0.2 0.52 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ87155.1 - 0.01 15.9 0.0 0.065 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DZR PF12773.2 EAQ87155.1 - 0.011 15.5 1.6 0.022 14.5 1.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon APS_kinase PF01583.15 EAQ87155.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 EAQ87155.1 - 0.014 15.2 0.0 0.066 13.1 0.0 2.1 2 1 0 2 2 1 0 AAA domain RNA_POL_M_15KD PF02150.11 EAQ87155.1 - 0.022 14.4 0.7 0.047 13.3 0.5 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Viral_helicase1 PF01443.13 EAQ87155.1 - 0.057 12.9 0.3 0.32 10.4 0.2 2.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 EAQ87155.1 - 0.082 10.6 0.3 0.4 8.3 0.1 1.9 2 0 0 2 2 2 0 Helicase zf-TFIIB PF13453.1 EAQ87155.1 - 0.093 11.9 4.0 0.22 10.7 2.8 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger RNHCP PF12647.2 EAQ87155.1 - 0.098 12.4 1.8 0.23 11.3 1.2 1.5 1 0 0 1 1 1 0 RNHCP domain UvrD_C_2 PF13538.1 EAQ87155.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DNA_ligase_ZBD PF03119.11 EAQ87155.1 - 0.39 10.4 2.9 1 9.1 2.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Rad60-SLD_2 PF13881.1 EAQ87156.1 - 2.5e-12 46.6 0.0 4.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAQ87156.1 - 3e-06 26.5 0.0 5.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EAQ87156.1 - 0.00017 21.7 0.1 0.00048 20.2 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EAQ87157.1 - 5e-22 78.2 0.0 8.1e-22 77.5 0.0 1.4 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 EAQ87158.1 - 1e-14 55.0 0.0 1.2e-09 38.5 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SbcCD_C PF13558.1 EAQ87158.1 - 5.7e-07 29.3 0.1 0.0025 17.6 0.1 2.4 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EAQ87158.1 - 5.7e-05 23.2 0.1 0.047 13.6 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EAQ87158.1 - 0.0036 18.0 0.0 0.0088 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAQ87158.1 - 0.012 15.5 0.0 3.8 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EAQ87158.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EAQ87158.1 - 0.039 13.9 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ApbA_C PF08546.6 EAQ87159.1 - 9.4e-37 125.7 0.1 1.5e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EAQ87159.1 - 4.6e-27 94.3 0.0 2.4e-26 91.9 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF939_C PF11728.3 EAQ87159.1 - 0.024 14.4 0.2 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 DUF939 C-terminal domain ExoD PF06055.7 EAQ87160.1 - 0.33 10.0 1.1 0.47 9.5 0.8 1.4 1 1 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Ribosomal_L24e PF01246.15 EAQ87161.1 - 3.6e-26 90.7 3.7 9.5e-26 89.4 2.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Ras PF00071.17 EAQ87162.1 - 1e-41 141.9 0.1 1.3e-41 141.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EAQ87162.1 - 2.1e-11 43.3 0.5 2.6e-11 43.0 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EAQ87162.1 - 2.1e-10 41.1 0.0 3.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EAQ87162.1 - 1.2e-06 28.1 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ87162.1 - 0.0093 15.1 0.1 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_tran_WbsX PF14307.1 EAQ87162.1 - 0.031 13.4 0.0 0.036 13.2 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase WbsX Glyco_hydro_3_C PF01915.17 EAQ87162.1 - 0.14 11.6 1.9 0.25 10.8 0.4 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Nop53 PF07767.6 EAQ87163.1 - 3.4e-87 292.9 38.9 3.6e-48 164.4 21.0 2.0 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) adh_short PF00106.20 EAQ87164.1 - 2e-20 73.3 0.5 4.4e-20 72.2 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ87164.1 - 1e-08 35.0 0.1 2.8e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EAQ87164.1 - 6.3e-07 29.4 0.1 7e-06 25.9 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ87164.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding TPR_15 PF13429.1 EAQ87164.1 - 0.13 11.3 0.2 0.29 10.1 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Epimerase PF01370.16 EAQ87164.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_61 PF03443.9 EAQ87165.1 - 6.5e-23 81.6 0.0 8.3e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AAA_16 PF13191.1 EAQ87166.1 - 6.2e-08 32.8 0.0 2e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EAQ87166.1 - 5.2e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ87166.1 - 9.6e-06 25.7 0.0 3.6e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EAQ87166.1 - 0.034 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Glyco_hydro_12 PF01670.11 EAQ87167.1 - 2.5e-50 170.2 3.3 4.8e-50 169.3 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_3 PF00933.16 EAQ87168.1 - 1e-32 113.3 0.0 1.6e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ87168.1 - 3.6e-32 111.7 0.8 5.1e-24 85.0 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Pyr_redox_2 PF07992.9 EAQ87169.1 - 4.6e-25 88.6 0.0 6.5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ87169.1 - 3.8e-16 59.2 0.0 3.7e-11 43.2 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EAQ87169.1 - 8.1e-07 27.9 0.1 2.3e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EAQ87169.1 - 1.7e-05 24.8 0.6 4.2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EAQ87169.1 - 3.8e-05 23.2 0.3 0.00013 21.5 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EAQ87169.1 - 0.00072 18.7 0.5 0.0017 17.6 0.3 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 EAQ87169.1 - 0.00091 19.3 0.0 2 8.4 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ87169.1 - 0.018 13.9 0.1 0.72 8.6 0.1 2.8 3 0 0 3 3 3 0 FAD binding domain EF-hand_8 PF13833.1 EAQ87169.1 - 0.059 12.9 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair NAD_binding_8 PF13450.1 EAQ87169.1 - 0.084 12.9 0.0 0.9 9.6 0.0 2.7 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PRK PF00485.13 EAQ87170.1 - 9.2e-56 188.4 0.0 1.3e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EAQ87170.1 - 8.9e-37 126.3 0.1 1.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EAQ87170.1 - 4.2e-09 37.2 0.1 1e-08 36.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ87170.1 - 7.1e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ87170.1 - 7e-05 22.7 0.0 0.001 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EAQ87170.1 - 0.00012 21.7 0.0 0.00045 19.8 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 EAQ87170.1 - 0.0041 17.4 0.1 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EAQ87170.1 - 0.0047 16.4 0.1 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EAQ87170.1 - 0.0066 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 EAQ87170.1 - 0.01 14.6 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 EAQ87170.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EAQ87170.1 - 0.036 13.8 0.1 0.087 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EAQ87170.1 - 0.053 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EAQ87170.1 - 0.065 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 EAQ87170.1 - 0.11 11.4 0.1 4.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 EAQ87170.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CLTH PF10607.4 EAQ87171.1 - 2.8e-34 117.8 0.1 4.2e-34 117.3 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EAQ87171.1 - 7e-09 35.1 0.2 1.8e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 LisH ETC_C1_NDUFA4 PF04800.7 EAQ87172.1 - 1.5e-37 127.5 0.2 2.3e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EAQ87173.1 - 1.2e-40 137.6 1.0 1.2e-40 137.6 0.7 2.5 2 0 0 2 2 2 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Aminotran_1_2 PF00155.16 EAQ87174.1 - 1.1e-09 37.7 0.0 3.7e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II RNase_H2_suC PF08615.6 EAQ87175.1 - 6.2e-27 94.1 0.0 8.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 EAQ87176.1 - 2.1e-12 46.7 0.0 2.4e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAQ87176.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RNase_T PF00929.19 EAQ87177.1 - 3.5e-22 79.4 0.0 5.8e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EAQ87177.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease DUF605 PF04652.11 EAQ87177.1 - 1.2 8.4 12.5 1.5 8.1 8.7 1.1 1 0 0 1 1 1 0 Vta1 like Penaeidin PF05927.6 EAQ87178.1 - 1.9 9.0 9.8 2.7 8.5 6.8 1.3 1 0 0 1 1 1 0 Penaeidin Clr5 PF14420.1 EAQ87181.1 - 1.4e-14 53.7 1.3 2.6e-14 52.8 0.9 1.4 1 0 0 1 1 1 1 Clr5 domain MOZ_SAS PF01853.13 EAQ87183.1 - 4.2e-85 283.7 0.5 6.9e-85 283.0 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EAQ87183.1 - 8.6e-19 66.9 0.8 1.4e-17 63.0 0.0 2.9 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain DUF2316 PF10078.4 EAQ87183.1 - 0.011 15.6 0.3 0.78 9.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Acetyltransf_1 PF00583.19 EAQ87183.1 - 0.036 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ87183.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MCM PF00493.18 EAQ87184.1 - 2e-137 457.4 0.4 3.7e-137 456.5 0.3 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAQ87184.1 - 2.3e-17 63.6 0.0 6.1e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAQ87184.1 - 1.9e-07 30.4 0.0 4.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EAQ87184.1 - 0.00094 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EAQ87184.1 - 0.002 17.7 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ87184.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Polysacc_deac_1 PF01522.16 EAQ87185.1 - 2.5e-16 59.4 0.0 4.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase AAA_29 PF13555.1 EAQ87185.1 - 0.056 12.9 0.6 0.12 11.8 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2334 PF10096.4 EAQ87185.1 - 0.069 12.5 0.0 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) MAP1B_neuraxin PF00414.12 EAQ87185.1 - 3.2 7.2 6.3 1.4 8.3 1.8 2.4 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat TRAPPC-Trs85 PF12739.2 EAQ87187.1 - 6.3e-119 397.3 3.2 1.1e-118 396.5 2.2 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SAP PF02037.22 EAQ87190.1 - 4.3e-07 29.2 0.1 7.5e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.1 EAQ87190.1 - 4.5e-06 26.5 19.2 6.1e-06 26.1 10.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ87190.1 - 4.6e-06 26.1 14.2 4.6e-06 26.1 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ87190.1 - 2.2e-05 24.0 13.4 2.2e-05 24.0 9.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAQ87190.1 - 2.3e-05 23.9 11.6 2.3e-05 23.9 8.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ87190.1 - 7.6e-05 22.4 14.0 7.6e-05 22.4 9.7 2.4 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.10 EAQ87190.1 - 8.2e-05 22.4 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_6 PF14835.1 EAQ87190.1 - 0.00033 20.3 5.0 0.00033 20.3 3.5 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EAQ87190.1 - 0.0046 16.8 13.9 0.0046 16.8 9.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAQ87190.1 - 0.013 15.2 9.2 0.013 15.2 6.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EAQ87190.1 - 0.3 10.9 4.4 0.48 10.2 2.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mob_synth_C PF06463.8 EAQ87190.1 - 0.31 10.7 7.3 0.076 12.6 2.6 1.7 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 EAQ87190.1 - 0.62 10.2 11.7 0.14 12.3 5.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-P11 PF03854.9 EAQ87190.1 - 6.5 6.3 13.1 7.6 6.0 6.5 2.3 2 0 0 2 2 2 0 P-11 zinc finger INCENP_ARK-bind PF03941.10 EAQ87191.1 - 1.5e-20 72.7 0.3 1.5e-20 72.7 0.2 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region CAF-1_p150 PF11600.3 EAQ87191.1 - 0.0013 18.1 25.8 0.0013 18.1 17.9 5.0 5 0 0 5 5 5 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 EAQ87191.1 - 1 6.9 21.4 1.3 6.6 3.6 2.2 2 0 0 2 2 2 0 Ycf1 DnaJ PF00226.26 EAQ87192.1 - 1.4e-17 63.2 1.4 2.6e-17 62.2 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Neur_chan_memb PF02932.11 EAQ87192.1 - 2.6 7.8 3.2 1.4 8.7 0.2 2.0 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PDZ_1 PF12812.2 EAQ87193.1 - 2.1e-55 184.5 0.0 1.3e-33 114.7 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 EAQ87193.1 - 6.5e-16 58.4 0.2 1.4e-13 50.8 0.0 2.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EAQ87193.1 - 1.2e-13 50.7 0.3 0.0001 22.0 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 EAQ87193.1 - 4.2e-07 30.0 0.0 0.019 15.1 0.0 4.0 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EAQ87193.1 - 0.00022 20.8 0.0 0.00064 19.3 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EAQ87193.1 - 0.015 15.1 0.3 1.4 8.7 0.0 3.4 4 0 0 4 4 4 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EAQ87193.1 - 0.16 11.4 0.1 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EAQ87193.1 - 0.17 10.2 0.1 0.34 9.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase S46 Avl9 PF09794.4 EAQ87194.1 - 1.4e-125 418.7 0.0 1e-68 231.5 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 EAQ87194.1 - 0.0028 16.9 2.7 0.3 10.3 0.0 3.3 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.20 EAQ87195.1 - 5.2e-73 245.4 0.0 6.4e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87195.1 - 1.2e-31 109.6 0.0 1.6e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ87195.1 - 2e-05 23.7 0.0 7.2e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ87195.1 - 0.00052 19.8 0.0 0.0013 18.4 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAQ87195.1 - 0.0012 17.8 0.0 0.023 13.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EAQ87195.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Phosphorylase PF00343.15 EAQ87196.1 - 0 1071.3 0.1 0 1071.1 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EAQ87196.1 - 0.033 13.8 0.0 0.091 12.4 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform G-alpha PF00503.15 EAQ87197.1 - 3.7e-125 417.6 0.4 4.4e-125 417.3 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAQ87197.1 - 5.8e-16 58.2 0.6 4.2e-10 39.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAQ87197.1 - 5.4e-05 22.4 0.8 0.11 11.6 0.1 2.6 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EAQ87197.1 - 0.0017 18.8 0.2 1.2 9.6 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EAQ87197.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.17 EAQ87198.1 - 8.7e-182 605.7 6.3 1.3e-181 605.1 4.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAQ87198.1 - 4.5e-26 90.4 5.7 4.5e-26 90.4 4.0 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain Rrf2 PF02082.15 EAQ87198.1 - 0.019 15.0 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DUF588 PF04535.7 EAQ87199.1 - 0.032 13.7 1.6 0.049 13.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF2569 PF10754.4 EAQ87199.1 - 1.1 9.4 5.6 1.3 9.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Mit_KHE1 PF10173.4 EAQ87200.1 - 5.5e-69 231.7 2.4 7.6e-69 231.3 1.6 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GATA PF00320.22 EAQ87202.1 - 1.6e-14 52.8 2.9 2.7e-14 52.1 2.0 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF2051 PF09738.4 EAQ87202.1 - 0.004 16.4 8.2 0.004 16.4 5.7 2.4 2 1 1 3 3 3 1 Double stranded RNA binding protein (DUF2051) IncA PF04156.9 EAQ87202.1 - 0.016 14.8 17.2 0.039 13.5 10.9 1.9 2 0 0 2 2 2 0 IncA protein TF_Zn_Ribbon PF08271.7 EAQ87202.1 - 0.067 12.5 0.3 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4164 PF13747.1 EAQ87202.1 - 0.074 13.1 13.7 0.16 12.0 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HAP1_N PF04849.8 EAQ87202.1 - 0.35 9.7 18.9 0.63 8.9 13.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF3584 PF12128.3 EAQ87202.1 - 0.62 7.3 19.6 0.15 9.3 10.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ADIP PF11559.3 EAQ87202.1 - 1.4 8.8 28.8 0.41 10.5 15.0 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EAQ87202.1 - 1.7 7.5 18.0 3.3 6.6 12.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EAQ87202.1 - 3 7.6 29.9 0.12 12.2 5.8 2.5 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_C58 PF03543.9 EAQ87202.1 - 4.5 6.7 9.6 8.3 5.8 3.7 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF4613 PF15390.1 EAQ87202.1 - 4.7 5.2 10.1 7.4 4.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Striatin PF08232.7 EAQ87202.1 - 5 7.4 23.7 3.7 7.8 4.3 3.0 2 1 1 3 3 3 0 Striatin family Fmp27_WPPW PF10359.4 EAQ87202.1 - 5.2 5.3 15.7 0.75 8.1 8.1 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain KH_4 PF13083.1 EAQ87203.1 - 0.095 12.3 0.1 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 KH domain Ribosomal_60s PF00428.14 EAQ87203.1 - 0.91 9.9 7.7 1.8 9.0 5.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ras PF00071.17 EAQ87206.1 - 1.5e-43 147.9 0.2 1.9e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ87206.1 - 1e-11 45.3 0.0 1.5e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EAQ87206.1 - 2.8e-06 26.9 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EAQ87206.1 - 0.00019 20.7 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EAQ87206.1 - 0.0063 15.7 0.1 0.0083 15.4 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B CP_ATPgrasp_2 PF14403.1 EAQ87206.1 - 0.025 13.2 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 MoCF_biosynth PF00994.19 EAQ87208.1 - 2e-19 69.4 0.0 4.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.15 EAQ87209.1 - 2.5e-08 33.8 0.0 2.9e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ParA PF10609.4 EAQ87210.1 - 8e-35 118.5 0.0 1.5e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EAQ87210.1 - 2.2e-15 56.6 0.0 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EAQ87210.1 - 1.4e-06 28.3 0.0 5.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EAQ87210.1 - 1.4e-06 27.5 0.0 8e-05 21.8 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EAQ87210.1 - 5e-05 22.5 0.0 0.00012 21.3 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EAQ87210.1 - 9.5e-05 21.8 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EAQ87210.1 - 0.0003 20.4 0.1 0.079 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ87210.1 - 0.00073 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EAQ87210.1 - 0.0018 17.9 0.7 0.026 14.2 0.4 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAQ87210.1 - 0.0035 16.9 0.5 0.0057 16.2 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ87210.1 - 0.0095 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EAQ87210.1 - 0.0098 15.3 0.1 0.019 14.4 0.0 1.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EAQ87210.1 - 0.016 14.4 0.0 0.086 12.0 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 EAQ87210.1 - 0.016 15.2 0.1 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EAQ87210.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EAQ87210.1 - 0.025 14.2 0.2 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EAQ87210.1 - 0.033 13.8 0.1 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EAQ87210.1 - 0.035 12.9 0.1 0.057 12.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EAQ87210.1 - 0.037 14.8 0.0 0.057 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EAQ87210.1 - 0.039 13.9 0.2 0.26 11.2 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EAQ87210.1 - 0.058 12.9 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EAQ87210.1 - 0.065 12.1 0.1 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EAQ87210.1 - 0.095 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 EAQ87210.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 EAQ87210.1 - 0.12 11.7 0.1 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein UPF0079 PF02367.12 EAQ87210.1 - 0.18 11.4 0.2 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EAQ87210.1 - 0.2 11.0 0.1 1.3 8.3 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain ECM11 PF15463.1 EAQ87211.1 - 1.1e-41 142.4 0.5 1.1e-41 142.4 0.4 3.5 3 1 1 4 4 4 1 Extracellular mutant protein 11 AAA_16 PF13191.1 EAQ87212.1 - 0.00011 22.2 0.0 0.00051 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAQ87212.1 - 0.00017 22.3 0.1 0.0019 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAQ87212.1 - 0.00094 19.4 0.1 0.0025 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ87212.1 - 0.0033 17.1 0.3 0.0072 15.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EAQ87212.1 - 0.006 16.2 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 EAQ87212.1 - 0.0074 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA PF00004.24 EAQ87212.1 - 0.0098 16.0 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EAQ87212.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EAQ87212.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.22 EAQ87212.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.5 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 EAQ87212.1 - 0.021 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EAQ87212.1 - 0.022 14.2 0.1 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EAQ87212.1 - 0.025 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EAQ87212.1 - 0.026 14.2 0.1 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EAQ87212.1 - 0.032 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain LpxK PF02606.9 EAQ87212.1 - 0.032 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_28 PF13521.1 EAQ87212.1 - 0.037 13.9 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAQ87212.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAQ87212.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EAQ87212.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EAQ87212.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EAQ87212.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_1 PF03029.12 EAQ87212.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 EAQ87213.1 - 2.5e-63 212.9 10.5 2.6e-32 112.0 0.3 2.7 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EAQ87213.1 - 2.6e-31 108.6 5.4 8.2e-15 54.9 0.1 3.1 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.14 EAQ87213.1 - 4.6e-31 106.7 0.0 8.8e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EAQ87213.1 - 8.4e-10 38.5 0.0 6.3e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 EAQ87213.1 - 1.8e-05 24.2 3.2 0.0031 16.9 0.0 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EAQ87213.1 - 0.0013 17.8 1.0 0.017 14.2 0.3 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 EAQ87213.1 - 0.04 14.2 1.4 3 8.1 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) 3HCDH_N PF02737.13 EAQ87213.1 - 2.7 7.6 7.0 3.1 7.4 0.7 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF500 PF04366.7 EAQ87214.1 - 6.3e-32 109.6 0.0 1.3e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF4445 PF14574.1 EAQ87214.1 - 0.082 11.1 0.4 3.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4445) Sigma70_ner PF04546.8 EAQ87214.1 - 0.77 9.3 10.4 0.14 11.7 3.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EAQ87214.1 - 4.5 7.6 8.0 0.64 10.3 0.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1660 PF07874.6 EAQ87217.1 - 6.5 7.1 12.2 20 5.5 1.7 3.9 3 0 0 3 3 3 0 Prophage protein (DUF1660) Actin PF00022.14 EAQ87218.1 - 1.9e-18 66.0 0.0 1.6e-15 56.4 0.0 2.4 3 0 0 3 3 3 2 Actin Ribonuc_L-PSP PF01042.16 EAQ87219.1 - 3.6e-27 94.5 0.1 5.1e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Kelch_5 PF13854.1 EAQ87220.1 - 1.8e-15 56.4 1.3 6.6e-12 45.1 0.7 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EAQ87220.1 - 2.9e-06 27.1 1.0 0.012 15.7 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EAQ87220.1 - 3.8e-06 26.8 5.7 2e-05 24.6 0.2 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 EAQ87220.1 - 1.4e-05 24.7 2.7 0.041 13.6 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EAQ87220.1 - 0.0014 18.1 0.3 0.22 11.1 0.2 2.9 2 0 0 2 2 2 1 Kelch motif Lactamase_B PF00753.22 EAQ87221.1 - 3.5e-14 52.8 0.6 1.3e-08 34.7 0.1 2.2 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily TrmE_N PF10396.4 EAQ87221.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Hexokinase_2 PF03727.11 EAQ87222.1 - 7.4e-20 71.1 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.11 EAQ87222.1 - 1.4e-17 63.4 50.1 2.4e-14 52.8 11.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Hexokinase_1 PF00349.16 EAQ87222.1 - 3.3e-13 49.4 0.0 1.4e-12 47.3 0.0 1.9 1 1 1 2 2 2 1 Hexokinase DcpS PF05652.7 EAQ87223.1 - 5.2e-31 107.3 0.0 7.7e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EAQ87223.1 - 6e-31 107.0 0.0 1.3e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2016 PF09436.5 EAQ87223.1 - 0.055 13.0 0.1 1 8.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2016) ASFV_J13L PF05568.6 EAQ87224.1 - 8.4 5.8 12.4 4.9 6.6 4.9 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein TFCD_C PF12612.3 EAQ87225.1 - 4e-35 120.9 2.9 6.9e-34 116.9 0.8 3.1 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EAQ87225.1 - 0.0017 18.2 0.7 0.072 13.2 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EAQ87225.1 - 0.12 12.7 0.4 2.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Glyco_hydro_76 PF03663.9 EAQ87226.1 - 2.4e-51 175.2 8.8 3e-51 174.9 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EAQ87226.1 - 0.0002 20.4 1.6 0.04 12.9 0.0 2.8 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 His_Phos_2 PF00328.17 EAQ87230.1 - 3.5e-130 434.3 0.1 4.5e-130 434.0 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EAQ87230.1 - 3e-07 30.0 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EAQ87231.1 - 8.4e-43 146.1 0.1 5.2e-38 130.4 0.0 2.2 1 1 1 2 2 2 2 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EAQ87231.1 - 1.9e-19 68.7 15.3 2.8e-05 23.8 0.5 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EAQ87231.1 - 0.00024 19.3 1.4 2 6.4 0.1 4.0 3 1 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ87231.1 - 0.012 14.4 0.3 2.6 6.7 0.0 2.8 3 0 0 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 EAQ87231.1 - 0.016 13.5 0.0 0.026 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain AA_permease PF00324.16 EAQ87232.1 - 4.9e-110 368.1 37.2 5.5e-110 367.9 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ87232.1 - 1e-19 70.4 40.5 1.3e-19 70.0 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 EAQ87232.1 - 0.7 9.6 5.7 0.3 10.8 1.7 2.0 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 JAB PF01398.16 EAQ87235.1 - 3.5e-09 36.4 0.0 1.2e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAQ87235.1 - 0.011 15.8 2.0 0.18 11.8 1.1 2.8 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Rick_17kDa_Anti PF05433.10 EAQ87235.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain ADH_N PF08240.7 EAQ87236.1 - 1.5e-25 89.1 1.7 2.5e-25 88.3 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ87236.1 - 1.6e-12 47.0 0.1 8.7e-12 44.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Vps5 PF09325.5 EAQ87237.1 - 3.9e-15 55.7 1.3 6e-15 55.1 0.9 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EAQ87237.1 - 5.5e-10 39.0 0.0 9.9e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 EAQ87237.1 - 0.13 12.1 1.6 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PAT1 PF09770.4 EAQ87237.1 - 0.56 8.3 17.3 0.88 7.7 12.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 EAQ87237.1 - 5.7 6.5 7.9 11 5.6 5.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 EAQ87237.1 - 7.2 5.8 22.6 13 5.0 15.6 1.4 1 0 0 1 1 1 0 Vta1 like GTP_EFTU PF00009.22 EAQ87238.1 - 8.7e-43 145.9 0.0 2.5e-42 144.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EAQ87238.1 - 6.5e-24 83.5 0.0 1.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EAQ87238.1 - 4.6e-12 45.6 0.0 1.3e-10 41.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus Spc7 PF08317.6 EAQ87239.1 - 0.0088 14.7 1.8 0.011 14.3 1.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.1 EAQ87239.1 - 0.018 14.4 4.5 0.21 11.0 3.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Angiomotin_C PF12240.3 EAQ87239.1 - 0.02 14.4 2.7 0.026 14.0 1.9 1.2 1 0 0 1 1 1 0 Angiomotin C terminal Lzipper-MIP1 PF14389.1 EAQ87239.1 - 0.02 15.0 3.3 0.033 14.2 2.3 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 EAQ87239.1 - 0.034 13.3 2.7 0.054 12.6 1.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EAQ87239.1 - 0.041 13.3 6.7 0.32 10.5 0.3 2.6 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.4 EAQ87239.1 - 0.052 13.6 3.1 0.16 12.1 2.2 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF512 PF04459.7 EAQ87239.1 - 0.064 12.3 0.1 0.084 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF4094 PF13334.1 EAQ87239.1 - 0.1 12.9 0.9 0.3 11.4 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) NPV_P10 PF05531.7 EAQ87239.1 - 0.13 12.5 0.4 0.49 10.6 0.0 2.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NifQ PF04891.7 EAQ87239.1 - 0.14 12.3 1.4 0.24 11.5 1.0 1.4 1 0 0 1 1 1 0 NifQ Herpes_UL25 PF01499.11 EAQ87239.1 - 0.19 9.9 4.2 0.22 9.7 2.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2857 PF11198.3 EAQ87239.1 - 0.22 10.9 2.9 0.78 9.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) Rho_Binding PF08912.6 EAQ87239.1 - 0.35 11.2 4.5 1.9 8.8 0.3 2.3 2 0 0 2 2 2 0 Rho Binding bZIP_1 PF00170.16 EAQ87239.1 - 0.39 10.6 5.9 3.8 7.5 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 EAQ87239.1 - 0.48 10.4 4.6 0.88 9.6 3.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Adeno_PIX PF03955.9 EAQ87239.1 - 1.3 9.5 4.3 2.2 8.8 1.0 2.2 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Ax_dynein_light PF10211.4 EAQ87239.1 - 1.8 8.3 7.3 2.9 7.6 0.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.6 EAQ87239.1 - 2.5 7.7 6.2 0.78 9.4 0.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 EAQ87239.1 - 5.7 7.4 6.7 3.8 8.0 0.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SMC_Nse1 PF07574.8 EAQ87241.1 - 6.9e-29 100.9 0.0 8.1e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex SPRY PF00622.23 EAQ87243.1 - 9.6e-09 35.3 0.1 3.6e-07 30.2 0.0 2.9 3 1 1 4 4 4 1 SPRY domain Myb_Cef PF11831.3 EAQ87244.1 - 2.6e-59 200.2 10.8 2.6e-59 200.2 7.5 3.0 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EAQ87244.1 - 2.3e-21 75.6 8.9 6e-15 55.1 2.2 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ87244.1 - 9.6e-21 73.5 4.1 1.5e-09 37.7 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EAQ87244.1 - 0.032 14.1 3.1 0.71 9.7 0.0 3.6 2 2 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF164 PF02591.10 EAQ87248.1 - 0.019 14.7 1.7 0.22 11.4 0.0 2.9 3 0 0 3 3 3 0 Putative zinc ribbon domain Pyr_redox_2 PF07992.9 EAQ87249.1 - 2.8e-11 43.6 0.0 1.1e-07 31.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ87249.1 - 3.1e-05 23.7 2.6 0.0053 16.5 0.0 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EAQ87249.1 - 9.4e-05 21.4 0.1 0.00032 19.7 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EAQ87249.1 - 0.00098 19.2 2.7 0.048 13.7 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ87249.1 - 0.017 13.9 3.1 0.28 9.9 0.0 2.1 1 1 1 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAQ87249.1 - 1.2 7.8 5.6 6.4 5.5 1.8 2.7 3 0 0 3 3 3 0 FAD binding domain DUF4360 PF14273.1 EAQ87250.1 - 1.9e-27 96.0 0.0 2.4e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SRP_SPB PF02978.14 EAQ87251.1 - 0.04 14.1 0.5 0.18 12.0 0.0 2.3 3 0 0 3 3 3 0 Signal peptide binding domain T4SS PF07996.6 EAQ87251.1 - 0.071 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins CENP-Q PF13094.1 EAQ87251.1 - 0.077 13.0 5.6 0.5 10.3 0.2 3.0 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit peroxidase PF00141.18 EAQ87253.1 - 1.6e-18 67.0 0.0 3.6e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 Peroxidase Inositol_P PF00459.20 EAQ87256.1 - 1.9e-63 214.3 0.1 2.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 EAQ87257.1 - 2.4e-18 65.9 33.8 6.3e-11 41.5 5.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ87257.1 - 3.9e-08 32.3 3.8 3.9e-08 32.3 2.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Dioxygenase_C PF00775.16 EAQ87259.1 - 1.3e-10 40.8 2.8 6.1e-10 38.6 2.0 2.0 1 1 0 1 1 1 1 Dioxygenase His_Phos_2 PF00328.17 EAQ87261.1 - 9.3e-56 189.6 0.0 1.1e-55 189.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SSP160 PF06933.6 EAQ87262.1 - 1.1 7.2 12.9 1.8 6.4 8.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec62 PF03839.11 EAQ87263.1 - 1.2e-54 185.1 0.2 1.2e-54 185.1 0.1 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 SelP_N PF04592.9 EAQ87263.1 - 0.03 13.7 13.1 0.056 12.8 9.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 EAQ87263.1 - 0.046 12.0 0.0 0.059 11.6 0.0 1.2 1 1 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EAQ87263.1 - 0.048 12.6 8.2 0.21 10.5 5.3 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter PKI PF02827.11 EAQ87263.1 - 2.9 8.0 5.4 2.5 8.2 0.0 2.6 2 1 0 2 2 2 0 cAMP-dependent protein kinase inhibitor APC_CDC26 PF10471.4 EAQ87263.1 - 6.4 7.5 21.2 2.2 9.0 10.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PLDc_2 PF13091.1 EAQ87264.1 - 2.4e-14 53.1 0.0 3.3e-06 26.8 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EAQ87264.1 - 5.4e-09 35.5 0.5 0.0031 17.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EAQ87264.1 - 0.12 11.3 0.0 0.29 10.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Thioredoxin PF00085.15 EAQ87265.1 - 4.5e-31 106.6 0.0 4.3e-25 87.4 0.0 3.3 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EAQ87265.1 - 5.5e-11 42.6 0.0 7.1e-05 22.6 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EAQ87265.1 - 1.6e-06 28.3 0.2 0.0026 17.9 0.1 3.8 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAQ87265.1 - 5.4e-05 23.2 0.2 0.0039 17.2 0.0 3.7 4 1 0 4 4 4 1 Thioredoxin-like HyaE PF07449.6 EAQ87265.1 - 0.00057 19.7 0.0 2.8 7.9 0.0 4.0 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EAQ87265.1 - 0.023 14.7 0.0 0.089 12.8 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like UBN_AB PF14075.1 EAQ87265.1 - 0.028 14.0 0.5 0.046 13.3 0.3 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Tyr-DNA_phospho PF06087.7 EAQ87266.1 - 1.1e-81 274.7 0.0 1.3e-81 274.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ACBP PF00887.14 EAQ87267.1 - 1e-17 63.5 1.6 1.3e-17 63.2 1.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein RTBV_P12 PF06361.6 EAQ87267.1 - 0.03 14.5 0.3 0.041 14.1 0.2 1.2 1 1 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Pyr_redox_2 PF07992.9 EAQ87268.1 - 1.6e-14 54.2 0.2 1e-13 51.6 0.2 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ87268.1 - 3e-06 27.4 0.3 0.00061 19.9 0.0 2.9 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ87268.1 - 4.2e-06 27.0 2.9 0.00072 19.9 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ87268.1 - 0.00019 20.4 0.0 0.021 13.7 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EAQ87268.1 - 0.0039 16.1 5.5 2.3 7.0 0.0 3.4 3 1 1 4 4 4 3 FAD dependent oxidoreductase End3 PF12761.2 EAQ87269.1 - 8.7e-73 244.1 0.9 1.2e-72 243.6 0.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EAQ87269.1 - 6.1e-50 167.2 0.0 1.9e-48 162.4 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EAQ87269.1 - 8.4e-07 27.8 0.2 1.8e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EAQ87269.1 - 4.6e-06 26.1 0.1 8.4e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EAQ87269.1 - 4e-05 23.6 0.0 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EAQ87269.1 - 0.00077 19.1 0.2 0.0026 17.4 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EAQ87269.1 - 0.0058 15.9 0.1 0.014 14.7 0.1 1.7 1 0 0 1 1 1 1 EF hand MDMPI_N PF11716.3 EAQ87269.1 - 0.014 15.8 1.9 0.029 14.7 0.0 2.4 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain CCDC-167 PF15188.1 EAQ87269.1 - 0.033 14.1 0.8 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mnd1 PF03962.10 EAQ87269.1 - 0.055 13.1 3.7 0.19 11.4 2.6 1.8 1 1 0 1 1 1 0 Mnd1 family COG2 PF06148.6 EAQ87269.1 - 0.63 9.9 3.3 0.8 9.5 0.1 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EAQ87269.1 - 4.7 6.7 7.9 77 2.8 5.5 2.4 1 1 0 1 1 1 0 IncA protein Mga PF05043.8 EAQ87271.1 - 0.054 13.7 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain DivIVA PF05103.8 EAQ87271.1 - 0.37 10.8 7.7 1.2 9.1 1.9 2.4 2 0 0 2 2 2 0 DivIVA protein PilJ PF13675.1 EAQ87271.1 - 0.52 10.6 10.1 1.5 9.2 1.5 2.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF972 PF06156.8 EAQ87271.1 - 2.2 8.6 11.3 1.3 9.3 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 EAQ87271.1 - 3.3 7.3 9.2 0.049 13.2 0.4 2.3 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF4164 PF13747.1 EAQ87271.1 - 7 6.8 15.4 3.3 7.9 4.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) GRAM PF02893.15 EAQ87272.1 - 2.6e-16 58.8 0.0 4.4e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain OPT PF03169.10 EAQ87273.1 - 2.6e-211 703.3 35.8 3e-211 703.1 24.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.15 EAQ87274.1 - 1.4e-23 83.6 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.7 EAQ87275.1 - 2.5e-27 95.5 0.2 1.3e-26 93.2 0.1 2.4 1 0 0 1 1 1 1 Exportin 1-like protein HEAT_EZ PF13513.1 EAQ87275.1 - 4.5 7.8 8.5 11 6.6 0.0 5.3 7 0 0 7 7 7 0 HEAT-like repeat TRM PF02005.11 EAQ87277.1 - 1.5e-106 356.5 0.0 4.1e-91 305.7 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EAQ87277.1 - 0.0028 17.6 0.5 0.0075 16.2 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain DAGK_cat PF00781.19 EAQ87278.1 - 7.4e-07 28.6 0.6 1.9e-06 27.3 0.0 1.8 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.22 EAQ87279.1 - 1.4e-30 106.3 1.4 1.9e-18 67.0 0.0 2.7 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EAQ87279.1 - 1.4e-12 48.2 2.0 0.0014 18.6 0.0 3.2 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EAQ87279.1 - 0.00075 18.7 0.4 1.2 8.2 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 EAQ87279.1 - 0.0035 17.1 0.4 0.0076 16.0 0.3 1.6 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 EAQ87279.1 - 0.0037 17.1 0.1 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EAQ87279.1 - 0.0061 16.5 5.7 0.0062 16.5 1.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EAQ87279.1 - 0.0088 15.9 0.7 1.8 8.5 0.0 3.6 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EAQ87279.1 - 0.024 14.1 0.2 0.053 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EAQ87279.1 - 0.03 14.4 2.5 0.55 10.3 0.1 3.3 3 1 0 3 3 3 0 AAA domain CobA_CobO_BtuR PF02572.10 EAQ87279.1 - 0.064 12.8 0.1 5.3 6.6 0.0 2.6 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_23 PF13476.1 EAQ87279.1 - 0.12 12.6 0.2 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 EAQ87280.1 - 1.7e-11 43.3 0.3 9.2e-06 24.4 0.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Lamp PF01299.12 EAQ87281.1 - 0.06 12.4 12.8 0.1 11.7 8.9 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) PRCC PF10253.4 EAQ87281.1 - 3.8 8.1 7.3 3.2 8.4 4.1 1.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pheromone PF08015.6 EAQ87281.1 - 8.8 7.2 15.5 17 6.3 0.4 2.9 2 1 1 3 3 3 0 Fungal mating-type pheromone SSP160 PF06933.6 EAQ87282.1 - 0.17 9.8 7.5 0.25 9.2 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-H2C2_2 PF13465.1 EAQ87288.1 - 2.9e-08 33.5 17.3 1.4e-05 25.1 3.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ87288.1 - 2.6e-07 30.5 16.9 0.0017 18.6 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ87288.1 - 0.00031 20.8 14.5 0.022 15.0 1.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Bromodomain PF00439.20 EAQ87291.1 - 4.5e-18 64.9 0.0 7.7e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 EAQ87291.1 - 0.0061 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TIM21 PF08294.6 EAQ87292.1 - 1.6e-25 89.5 0.0 2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EAQ87292.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 EAQ87293.1 - 5.6e-27 93.8 0.2 1.1e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NDT80_PhoG PF05224.7 EAQ87295.1 - 1.3e-32 113.3 0.2 2e-24 86.6 0.0 2.3 1 1 1 2 2 2 2 NDT80 / PhoG like DNA-binding family DUF3459 PF11941.3 EAQ87296.1 - 0.023 14.8 0.1 0.066 13.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3459) DUF3716 PF12511.3 EAQ87298.1 - 0.053 13.1 1.3 0.061 12.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Pterin_bind PF00809.17 EAQ87300.1 - 4.4e-57 192.8 0.0 3.2e-56 190.0 0.0 2.2 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EAQ87300.1 - 5.4e-40 136.0 0.0 9.1e-40 135.3 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EAQ87301.1 - 1.5e-71 241.2 0.3 2e-71 240.8 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAQ87301.1 - 4.9e-09 35.5 0.5 1.1e-08 34.3 0.3 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAQ87301.1 - 1.6e-07 30.5 1.3 2.4e-07 29.9 0.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EAQ87301.1 - 0.052 12.4 0.7 0.19 10.6 0.2 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.9 EAQ87301.1 - 0.1 11.5 0.3 0.37 9.7 0.2 1.8 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase SUR7 PF06687.7 EAQ87302.1 - 2.2e-10 40.4 0.0 2.6e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EAQ87302.1 - 0.014 14.2 1.0 0.018 13.9 0.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Claudin_2 PF13903.1 EAQ87302.1 - 0.069 12.8 10.9 1.8 8.2 7.5 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction LEA_4 PF02987.11 EAQ87302.1 - 0.13 12.1 2.2 0.38 10.6 1.5 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein MT0933_antitox PF14013.1 EAQ87302.1 - 0.56 10.3 21.9 0.3 11.2 7.4 3.9 2 1 1 3 3 3 0 MT0933-like antitoxin protein DUF1700 PF08006.6 EAQ87302.1 - 5 6.3 6.5 9.1 5.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) MscL PF01741.13 EAQ87303.1 - 4.4e-14 52.7 0.2 9.4e-14 51.6 0.1 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL HpaP PF09483.5 EAQ87304.1 - 0.014 15.3 8.7 0.02 14.8 6.0 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Glyco_hydro_76 PF03663.9 EAQ87306.1 - 2.7e-132 441.6 2.4 3.3e-132 441.3 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EAQ87306.1 - 0.033 12.4 0.6 0.078 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) GlcNAc_2-epim PF07221.6 EAQ87306.1 - 0.14 11.1 1.9 0.38 9.6 0.3 2.2 2 1 1 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_88 PF07470.8 EAQ87306.1 - 0.23 10.4 3.4 8.3 5.3 0.0 2.9 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 EAQ87307.1 - 2.2e-58 197.9 0.0 2.6e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_GDSL PF00657.17 EAQ87308.1 - 5e-15 55.9 0.1 6.2e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAQ87308.1 - 2.1e-06 27.9 1.2 5.1e-05 23.4 0.8 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Zip PF02535.17 EAQ87309.1 - 1.5 7.7 5.2 2.2 7.1 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EAQ87309.1 - 3.1 5.9 15.1 4.6 5.3 10.5 1.2 1 0 0 1 1 1 0 Transmembrane protein RabGAP-TBC PF00566.13 EAQ87310.1 - 7.1e-48 162.9 0.5 5.9e-47 159.9 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF972 PF06156.8 EAQ87310.1 - 0.0012 19.1 5.9 0.0057 16.9 0.6 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 EAQ87310.1 - 0.0082 15.9 8.9 0.0082 15.9 6.2 2.8 3 0 0 3 3 3 1 Tropomyosin like Laminin_II PF06009.7 EAQ87310.1 - 0.068 12.9 14.4 0.024 14.3 1.9 2.8 3 0 0 3 3 2 0 Laminin Domain II Myosin_tail_1 PF01576.14 EAQ87310.1 - 0.094 10.4 21.2 0.0091 13.7 5.4 2.8 3 0 0 3 3 3 0 Myosin tail CENP-F_leu_zip PF10473.4 EAQ87310.1 - 0.1 12.4 23.8 0.019 14.8 6.2 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EAQ87310.1 - 0.12 12.3 25.7 0.031 14.1 8.0 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 EAQ87310.1 - 0.19 11.6 13.9 1.4 8.8 4.4 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fmp27_WPPW PF10359.4 EAQ87310.1 - 0.22 9.9 10.8 0.017 13.5 3.0 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4201 PF13870.1 EAQ87310.1 - 0.25 10.7 19.8 0.2 11.0 5.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) HR1 PF02185.11 EAQ87310.1 - 0.29 10.9 19.8 0.41 10.4 3.6 3.9 3 0 0 3 3 3 0 Hr1 repeat IncA PF04156.9 EAQ87310.1 - 0.37 10.3 25.3 0.31 10.6 4.8 3.5 4 0 0 4 4 3 0 IncA protein APG6 PF04111.7 EAQ87310.1 - 0.39 9.7 15.6 0.38 9.7 3.5 3.0 3 0 0 3 3 3 0 Autophagy protein Apg6 MitMem_reg PF13012.1 EAQ87310.1 - 0.63 10.1 7.1 1.3 9.1 1.0 3.7 4 1 0 4 4 3 0 Maintenance of mitochondrial structure and function Filament PF00038.16 EAQ87310.1 - 0.76 9.1 16.5 0.091 12.2 4.7 2.8 3 0 0 3 3 3 0 Intermediate filament protein XkdW PF09636.5 EAQ87310.1 - 1.1 9.2 3.8 2.2 8.2 0.3 2.7 2 0 0 2 2 2 0 XkdW protein HAUS-augmin3 PF14932.1 EAQ87310.1 - 1.9 7.6 11.8 0.22 10.7 1.5 3.3 4 0 0 4 4 4 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.1 EAQ87310.1 - 2.1 6.6 11.8 0.1 11.0 4.1 1.6 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EAQ87310.1 - 2.4 5.3 26.7 0.16 9.2 9.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) GAS PF13851.1 EAQ87310.1 - 2.7 7.1 20.9 0.029 13.5 5.0 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Prominin PF05478.6 EAQ87310.1 - 3.5 5.0 11.7 0.063 10.8 2.0 2.0 2 0 0 2 2 2 0 Prominin Atg14 PF10186.4 EAQ87310.1 - 3.6 6.4 16.9 1.7 7.5 6.1 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EAQ87310.1 - 4 7.9 16.2 6.8 7.1 3.8 4.3 4 1 0 4 4 4 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.4 EAQ87310.1 - 4.1 7.3 10.0 19 5.1 7.0 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein Spc7 PF08317.6 EAQ87310.1 - 4.2 5.9 19.3 0.075 11.6 4.0 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein IFT57 PF10498.4 EAQ87310.1 - 4.8 5.8 11.2 0.24 10.0 2.0 2.5 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.5 EAQ87310.1 - 4.9 7.2 8.5 1.7 8.7 2.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 EAQ87310.1 - 6 6.3 14.2 1.2 8.6 3.4 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EAQ87310.1 - 6.4 6.5 9.9 0.27 11.0 1.9 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.19 EAQ87310.1 - 6.5 6.4 8.0 1.9 8.1 2.2 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ScpA_ScpB PF02616.9 EAQ87310.1 - 9.8 5.6 11.7 0.35 10.4 2.8 2.3 3 0 0 3 3 2 0 ScpA/B protein Reticulon PF02453.12 EAQ87311.1 - 2.6e-40 137.7 5.5 3.7e-40 137.2 3.8 1.2 1 0 0 1 1 1 1 Reticulon DNA_topoisoIV PF00521.15 EAQ87312.1 - 1.9e-125 419.0 0.1 3.5e-125 418.2 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EAQ87312.1 - 5.1e-33 113.7 1.5 1.3e-32 112.3 1.1 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EAQ87312.1 - 1.1e-12 47.7 0.7 1.7e-11 43.9 0.0 3.1 3 0 0 3 3 3 1 Toprim domain HATPase_c PF02518.21 EAQ87312.1 - 5.9e-10 38.8 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 EAQ87315.1 - 1.2e-08 34.4 11.3 0.0031 17.1 0.3 3.4 2 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 EAQ87315.1 - 2.8e-07 29.9 5.4 0.022 14.6 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ87315.1 - 4.7e-07 29.1 4.4 0.017 14.7 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ87315.1 - 0.66 10.3 2.6 0.61 10.4 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Dynamin_N PF00350.18 EAQ87316.1 - 4.7e-13 49.2 0.0 4.7e-13 49.2 0.0 3.1 4 1 0 4 4 3 1 Dynamin family IncA PF04156.9 EAQ87316.1 - 0.00015 21.4 0.5 0.00015 21.4 0.3 4.0 4 0 0 4 4 4 1 IncA protein MMR_HSR1 PF01926.18 EAQ87316.1 - 0.0008 19.3 0.0 0.016 15.1 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ87316.1 - 0.0054 17.2 0.2 0.026 15.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EAQ87316.1 - 0.015 15.6 2.0 0.045 14.0 0.0 2.7 3 0 0 3 3 2 0 ABC transporter DUF258 PF03193.11 EAQ87316.1 - 0.031 13.4 0.0 0.42 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ87316.1 - 0.07 13.1 0.1 0.07 13.1 0.0 3.5 5 2 0 5 5 4 0 AAA ATPase domain AAA_22 PF13401.1 EAQ87316.1 - 0.13 12.4 0.8 1.3 9.1 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EAQ87316.1 - 0.17 12.6 1.9 0.33 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF4618 PF15397.1 EAQ87316.1 - 0.19 11.0 14.1 2.7 7.2 3.4 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4618) Pap_E4 PF02711.9 EAQ87316.1 - 0.23 12.3 4.4 0.76 10.6 3.1 2.0 1 0 0 1 1 1 0 E4 protein Adeno_IVa2 PF02456.10 EAQ87316.1 - 0.23 10.0 0.0 0.46 9.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein NPV_P10 PF05531.7 EAQ87316.1 - 2.5 8.4 5.8 3.2 8.0 0.0 3.9 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein cwf21 PF08312.7 EAQ87316.1 - 6 6.8 14.0 66 3.4 0.2 3.8 2 1 0 2 2 2 0 cwf21 domain DUF4140 PF13600.1 EAQ87316.1 - 6.6 7.2 11.7 1.8 9.0 0.1 4.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) NmrA PF05368.8 EAQ87317.1 - 7.9e-47 159.4 0.2 1.1e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ87317.1 - 4.5e-13 49.5 0.6 6.6e-13 49.0 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EAQ87317.1 - 0.0024 17.8 0.1 0.0055 16.6 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EAQ87317.1 - 0.018 14.0 1.9 0.051 12.5 1.4 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EAQ87317.1 - 0.019 13.6 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_43 PF04616.9 EAQ87318.1 - 4.3e-48 163.8 8.5 5.4e-48 163.5 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EAQ87318.1 - 6.5e-28 97.3 0.8 6.5e-28 97.3 0.6 2.2 3 0 0 3 3 3 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EAQ87318.1 - 0.046 13.0 4.8 0.085 12.2 3.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Phage_DNA_bind PF02303.12 EAQ87318.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-destabilising protein FAD_binding_4 PF01565.18 EAQ87319.1 - 1e-22 80.1 3.0 1.5e-22 79.5 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ87319.1 - 9.1e-13 47.9 0.0 2.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 EAQ87319.1 - 0.14 11.4 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain RVT_1 PF00078.22 EAQ87320.1 - 4e-20 72.0 0.1 1.4e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ87320.1 - 2.5e-16 59.8 1.3 5.2e-16 58.8 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.5 EAQ87320.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EAQ87320.1 - 0.18 12.2 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease HLH PF00010.21 EAQ87321.1 - 2.3e-08 33.6 0.0 5.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sulfate_transp PF00916.15 EAQ87322.1 - 2.9e-82 275.8 5.0 4.8e-82 275.1 3.5 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAQ87322.1 - 2.7e-29 100.6 3.1 2.7e-29 100.6 2.2 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EAQ87322.1 - 8.2e-09 34.9 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain AAA PF00004.24 EAQ87323.1 - 2.9e-11 43.7 0.0 5.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ87323.1 - 1.1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAQ87323.1 - 5.2e-05 22.4 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EAQ87323.1 - 0.00023 21.0 0.0 0.00066 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAQ87323.1 - 0.00061 19.5 0.0 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAQ87323.1 - 0.00075 19.2 0.0 0.0028 17.3 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EAQ87323.1 - 0.0059 16.6 0.2 0.04 13.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAQ87323.1 - 0.0066 17.2 0.0 0.024 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EAQ87323.1 - 0.0082 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EAQ87323.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ87323.1 - 0.017 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 EAQ87323.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DNA_pol3_delta PF06144.8 EAQ87323.1 - 0.35 10.3 0.0 0.53 9.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF1772 PF08592.6 EAQ87328.1 - 6.9e-13 48.5 9.3 9.2e-09 35.1 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) DUF998 PF06197.8 EAQ87328.1 - 0.0029 16.9 0.5 0.0029 16.9 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF998) Amidohydro_1 PF01979.15 EAQ87330.1 - 1.7e-36 126.5 0.1 2.2e-36 126.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EAQ87330.1 - 1.8e-08 34.0 4.1 1.2e-06 28.0 1.3 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EAQ87330.1 - 5.7e-06 26.5 10.6 0.0017 18.4 4.7 2.7 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EAQ87330.1 - 1.8e-05 24.4 0.0 4.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase ACPS PF01648.15 EAQ87331.1 - 7.6e-18 64.4 0.0 1.1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short_C2 PF13561.1 EAQ87332.1 - 2.1e-19 70.2 0.0 4.3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EAQ87332.1 - 1.9e-07 30.9 0.1 5.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EAQ87332.1 - 5.2e-05 23.2 0.5 0.00032 20.6 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ketoacyl-synt PF00109.21 EAQ87332.1 - 0.00012 21.6 0.0 0.04 13.3 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ87332.1 - 0.0018 17.9 0.2 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 KR domain Nuc-transf PF10127.4 EAQ87332.1 - 0.057 12.7 0.2 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Predicted nucleotidyltransferase Acyl_transf_1 PF00698.16 EAQ87333.1 - 1e-80 271.5 0.0 1.1e-78 264.7 0.0 3.3 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EAQ87333.1 - 5.7e-38 129.0 0.0 1.5e-37 127.7 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EAQ87333.1 - 7.6e-31 105.6 0.1 4.7e-30 103.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EAQ87333.1 - 2.6e-24 85.4 0.2 1.6e-23 82.9 0.0 2.5 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase PBP_GOBP PF01395.17 EAQ87333.1 - 0.54 9.8 0.1 1.1 8.9 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family SH3_1 PF00018.23 EAQ87336.1 - 1.1e-11 43.9 0.4 3.3e-11 42.4 0.3 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAQ87336.1 - 2.6e-11 42.9 0.4 1.2e-10 40.8 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EAQ87336.1 - 8.3e-10 38.0 0.1 9.9e-09 34.5 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain CDC45 PF02724.9 EAQ87336.1 - 3.7 5.4 8.9 7.2 4.5 6.2 1.4 1 0 0 1 1 1 0 CDC45-like protein RPAP2_Rtr1 PF04181.8 EAQ87337.1 - 9.3e-16 57.6 0.0 1.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family FlgD PF03963.9 EAQ87337.1 - 0.61 10.1 3.5 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Ribosomal_S17e PF00833.13 EAQ87338.1 - 3.1e-59 198.0 0.2 3.7e-59 197.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EAQ87338.1 - 0.13 13.0 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EAQ87339.1 - 7.9e-94 314.3 0.0 5.1e-81 272.3 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit TGT PF01702.13 EAQ87340.1 - 7.9e-87 290.4 0.0 9.7e-87 290.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.14 EAQ87343.1 - 5e-61 206.6 0.1 7.5e-61 206.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Abhydrolase_6 PF12697.2 EAQ87344.1 - 1.5e-29 103.4 0.6 9.5e-29 100.8 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87344.1 - 2.1e-15 56.9 0.0 5.8e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ87344.1 - 3.1e-12 46.4 0.0 5.8e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EAQ87344.1 - 7e-06 25.3 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EAQ87344.1 - 0.00018 21.0 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EAQ87344.1 - 0.0019 18.4 0.5 0.0069 16.6 0.1 2.2 2 1 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.3 EAQ87344.1 - 0.0022 17.8 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EAQ87344.1 - 0.0028 17.2 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EAQ87344.1 - 0.025 14.0 0.0 7.1 6.0 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EAQ87344.1 - 0.057 12.2 0.0 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EAQ87344.1 - 0.092 12.3 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EAQ87344.1 - 0.13 11.7 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Spo7 PF03907.8 EAQ87345.1 - 5.1e-68 228.7 0.0 6.7e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Herpes_LP PF03363.8 EAQ87345.1 - 0.21 11.1 0.1 0.21 11.1 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus leader protein DSPc PF00782.15 EAQ87346.1 - 1.2e-13 50.8 0.0 2.7e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAQ87346.1 - 0.078 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltransf_18 PF12847.2 EAQ87347.1 - 0.0014 19.2 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ87347.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ87347.1 - 0.0098 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EAQ87347.1 - 0.036 13.2 0.0 0.059 12.5 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 EAQ87347.1 - 0.05 12.6 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 EAQ87347.1 - 0.071 12.2 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EAQ87347.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.15 EAQ87348.1 - 7.9e-44 149.9 0.0 8.1e-23 81.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ87348.1 - 2.2e-13 50.6 1.1 1.6e-12 47.8 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87348.1 - 0.0075 16.0 0.1 0.082 12.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EAQ87348.1 - 0.041 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Tho2 PF11262.3 EAQ87349.1 - 1.2e-89 300.3 0.1 1.6e-89 299.9 0.1 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EAQ87349.1 - 3.8e-29 100.2 0.1 7.4e-29 99.3 0.1 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit WSC PF01822.14 EAQ87350.1 - 6.3e-14 51.6 3.6 1.7e-13 50.3 2.5 1.7 1 1 0 1 1 1 1 WSC domain Syndecan PF01034.15 EAQ87350.1 - 0.0072 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Adeno_E3_CR2 PF02439.10 EAQ87350.1 - 0.022 14.2 0.9 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EAQ87350.1 - 0.071 11.3 0.0 0.098 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E P12 PF12669.2 EAQ87350.1 - 0.15 12.2 1.4 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Virus attachment protein p12 family SKG6 PF08693.5 EAQ87350.1 - 0.35 10.2 5.3 0.72 9.2 3.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.5 EAQ87351.1 - 0.00022 20.4 0.9 0.00069 18.8 0.0 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain YajC PF02699.10 EAQ87351.1 - 0.071 12.7 0.1 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit ERM PF00769.14 EAQ87351.1 - 0.2 11.1 4.9 0.43 10.0 3.4 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF221 PF02714.10 EAQ87352.1 - 2.8e-108 361.6 24.4 2.8e-108 361.6 16.9 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAQ87352.1 - 1.9e-44 150.9 0.8 1.9e-44 150.9 0.5 3.3 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EAQ87352.1 - 1.8e-31 107.8 0.0 4.4e-31 106.6 0.0 1.7 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EAQ87352.1 - 3.2e-23 82.0 0.1 5.2e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) GMC_oxred_N PF00732.14 EAQ87353.1 - 4.1e-51 173.8 0.0 1.6e-24 86.6 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ87353.1 - 3.9e-23 82.3 0.1 9.7e-23 81.0 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAQ87353.1 - 0.02 14.9 0.1 0.02 14.9 0.0 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ87353.1 - 0.039 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.13 EAQ87354.1 - 7.8e-18 64.2 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ87354.1 - 1.6e-09 37.5 8.9 3.2e-09 36.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence PF06911.7 EAQ87356.1 - 7.1e-49 165.9 2.5 1e-48 165.3 1.7 1.3 1 0 0 1 1 1 1 Senescence-associated protein Spc97_Spc98 PF04130.8 EAQ87357.1 - 8.1e-65 219.1 0.0 1e-64 218.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Serglycin PF04360.7 EAQ87357.1 - 0.098 12.3 8.2 0.17 11.6 5.2 1.7 2 0 0 2 2 2 0 Serglycin FAR1 PF03101.10 EAQ87358.1 - 2.1e-06 28.1 0.1 4.7e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF4200 PF13863.1 EAQ87358.1 - 0.019 14.8 8.7 0.035 14.0 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FadA PF09403.5 EAQ87358.1 - 0.02 14.9 0.5 0.037 14.0 0.3 1.4 1 0 0 1 1 1 0 Adhesion protein FadA Med9 PF07544.8 EAQ87358.1 - 8.9 6.1 10.5 0.59 9.9 3.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_6 PF12774.2 EAQ87359.1 - 5.8e-78 261.5 0.0 1.8e-77 259.9 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 EAQ87359.1 - 2.6e-75 253.8 0.0 2.6e-75 253.8 0.0 1.8 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 EAQ87359.1 - 1.1e-42 145.4 0.2 3.4e-42 143.8 0.1 1.9 2 0 0 2 2 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EAQ87359.1 - 7.1e-42 143.2 0.5 2.2e-40 138.3 0.1 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 EAQ87359.1 - 2.9e-39 134.8 8.0 4.8e-39 134.0 5.6 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EAQ87359.1 - 1.4e-33 115.5 0.2 6.1e-12 45.4 0.0 6.6 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EAQ87359.1 - 1.6e-21 76.6 0.0 5.1e-20 71.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EAQ87359.1 - 9.7e-17 61.3 0.0 0.0077 16.3 0.0 5.9 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 EAQ87359.1 - 3.8e-14 53.0 0.0 0.00096 19.3 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAQ87359.1 - 2.8e-11 44.2 0.0 0.015 16.0 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EAQ87359.1 - 1.5e-10 41.0 1.8 0.19 11.6 0.0 5.3 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.1 EAQ87359.1 - 8e-10 39.1 1.1 0.013 15.7 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.1 EAQ87359.1 - 1.6e-09 38.0 11.8 0.063 13.2 0.0 7.4 6 1 2 8 8 8 2 AAA ATPase domain T2SE PF00437.15 EAQ87359.1 - 1.6e-07 30.4 0.0 0.026 13.4 0.0 3.9 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 EAQ87359.1 - 1.8e-07 30.5 0.0 0.11 12.0 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.1 EAQ87359.1 - 2e-07 30.9 0.0 0.11 12.4 0.0 5.3 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EAQ87359.1 - 2.2e-06 27.3 0.0 0.46 10.2 0.0 4.4 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EAQ87359.1 - 2e-05 23.8 3.9 0.26 10.3 0.0 4.5 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EAQ87359.1 - 0.00015 22.0 2.7 1.8 8.8 0.0 4.7 4 0 0 4 4 3 1 ABC transporter IstB_IS21 PF01695.12 EAQ87359.1 - 0.00033 20.1 0.8 0.16 11.3 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF258 PF03193.11 EAQ87359.1 - 0.00077 18.6 0.0 7.8 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EAQ87359.1 - 0.0011 18.4 4.3 8.3 5.8 0.0 4.6 6 0 0 6 6 5 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EAQ87359.1 - 0.0013 17.8 6.1 0.5 9.4 0.0 4.4 5 0 0 5 5 4 2 Zeta toxin RNA_helicase PF00910.17 EAQ87359.1 - 0.0017 18.5 0.1 19 5.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase NACHT PF05729.7 EAQ87359.1 - 0.0032 17.1 1.6 15 5.1 0.0 4.8 5 0 0 5 5 4 0 NACHT domain MobB PF03205.9 EAQ87359.1 - 0.0057 16.3 0.1 6.4 6.4 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EAQ87359.1 - 0.007 15.7 3.9 0.16 11.3 0.0 3.8 5 0 0 5 5 4 1 AAA domain PduV-EutP PF10662.4 EAQ87359.1 - 0.061 12.8 1.1 3.8 7.0 0.1 3.7 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EAQ87359.1 - 0.34 10.3 9.4 6.6 6.0 0.2 4.6 5 0 0 5 5 5 0 AAA-like domain AAA_24 PF13479.1 EAQ87359.1 - 0.47 9.9 3.9 14 5.1 0.0 3.8 4 0 0 4 4 3 0 AAA domain DUF3867 PF12983.2 EAQ87359.1 - 0.85 9.5 4.9 0.45 10.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) PHP PF02811.14 EAQ87360.1 - 0.00068 19.4 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 PHP domain Dynamin_M PF01031.15 EAQ87361.1 - 2.3e-14 52.8 0.1 1.4e-13 50.2 0.0 2.4 4 0 0 4 4 4 1 Dynamin central region GED PF02212.13 EAQ87361.1 - 3.3e-05 23.7 0.4 9.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_N PF00350.18 EAQ87361.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Dynamin family FAA_hydrolase_N PF09298.6 EAQ87361.1 - 0.04 13.9 0.2 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF1539 PF07560.6 EAQ87361.1 - 0.074 12.9 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Fungal_trans PF04082.13 EAQ87362.1 - 4.8e-28 97.7 0.0 1.1e-27 96.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4306 PF14154.1 EAQ87362.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Clr5 PF14420.1 EAQ87364.1 - 1.3e-10 41.0 1.2 2.1e-10 40.3 0.9 1.4 1 0 0 1 1 1 1 Clr5 domain XendoU PF09412.5 EAQ87364.1 - 0.18 10.7 0.1 0.28 10.1 0.1 1.2 1 0 0 1 1 1 0 Endoribonuclease XendoU DUF1774 PF08611.5 EAQ87365.1 - 2.5e-14 53.1 3.5 2.5e-14 53.1 2.4 2.6 2 2 1 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF4051 PF13260.1 EAQ87365.1 - 4.6 6.6 6.3 0.88 8.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) UvrD_C_2 PF13538.1 EAQ87366.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PQQ PF01011.16 EAQ87370.1 - 1.3e-07 30.7 7.4 0.35 10.4 0.2 4.7 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_2 PF13360.1 EAQ87370.1 - 5.4e-07 29.3 1.6 0.0039 16.6 0.0 3.3 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 EAQ87370.1 - 0.00046 20.3 3.0 0.2 12.0 0.0 4.4 4 0 0 4 4 4 2 PQQ-like domain SNF2_N PF00176.18 EAQ87371.1 - 2.6e-41 141.3 0.2 4.2e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ87371.1 - 4.2e-09 36.1 0.0 8.3e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EAQ87371.1 - 2.9e-05 23.6 13.9 5.4e-05 22.7 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ87371.1 - 3.5e-05 23.7 13.9 6.3e-05 22.9 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ87371.1 - 0.0001 21.9 12.8 0.00019 21.0 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAQ87371.1 - 0.00013 21.5 10.3 0.00023 20.7 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ87371.1 - 0.00043 20.0 12.1 0.00083 19.1 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAQ87371.1 - 0.0015 18.3 9.1 0.0041 16.9 6.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EAQ87371.1 - 0.014 15.4 3.9 0.039 14.0 2.7 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EAQ87371.1 - 0.067 12.9 5.7 0.14 11.9 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EAQ87371.1 - 0.4 10.4 6.3 1.1 9.0 4.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EAQ87371.1 - 7.9 6.1 9.9 17 5.0 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nudix_N_2 PF14803.1 EAQ87371.1 - 8.6 6.1 8.9 2.8 7.6 3.7 2.1 2 0 0 2 2 2 0 Nudix N-terminal Ank_2 PF12796.2 EAQ87372.1 - 2.5e-47 159.1 18.7 3.4e-09 36.9 0.0 12.5 4 2 5 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ87372.1 - 7.3e-25 85.4 26.1 0.00032 20.3 0.0 17.1 17 1 0 17 17 17 7 Ankyrin repeat Ank_4 PF13637.1 EAQ87372.1 - 1.9e-17 63.2 12.8 0.0016 18.8 0.0 12.3 16 1 0 16 16 16 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ87372.1 - 3.2e-14 51.5 19.2 0.1 12.9 0.0 16.1 21 1 0 21 21 21 3 Ankyrin repeat Ank_5 PF13857.1 EAQ87372.1 - 6.9e-09 35.6 19.3 0.0075 16.4 0.0 11.6 12 2 2 14 14 14 1 Ankyrin repeats (many copies) Phage_lysozyme PF00959.14 EAQ87372.1 - 0.13 12.6 0.0 23 5.3 0.0 2.9 3 0 0 3 3 3 0 Phage lysozyme HET PF06985.6 EAQ87373.1 - 3.6e-29 101.6 0.0 6.6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 EAQ87374.1 - 3.2e-13 49.3 0.0 5.1e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3060 PF11259.3 EAQ87374.1 - 0.029 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) ABC2_membrane PF01061.19 EAQ87375.1 - 1.1e-21 77.0 18.1 1.7e-21 76.3 12.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EAQ87375.1 - 3.7e-20 72.6 0.0 6.8e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EAQ87375.1 - 2.9e-05 23.5 0.0 0.00045 19.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EAQ87375.1 - 4.9e-05 23.4 0.0 0.052 13.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ87375.1 - 0.00046 20.2 0.3 0.0026 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAQ87375.1 - 0.0013 19.5 0.0 0.0083 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ87375.1 - 0.0014 17.8 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAQ87375.1 - 0.0014 18.7 0.0 0.0043 17.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain DUF2791 PF10923.3 EAQ87375.1 - 0.0081 14.8 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA PF00004.24 EAQ87375.1 - 0.021 15.0 0.0 0.12 12.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAQ87375.1 - 0.027 14.3 0.0 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EAQ87375.1 - 0.041 13.2 0.1 0.079 12.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EAQ87375.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ87375.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EAQ87375.1 - 0.094 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EAQ87375.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EAQ87375.1 - 0.12 12.3 0.0 0.37 10.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EAQ87375.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EAQ87375.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EAQ87375.1 - 0.18 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 EAQ87375.1 - 0.22 11.1 0.0 0.46 10.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase SMC_N PF02463.14 EAQ87375.1 - 0.26 10.5 0.0 16 4.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FA_hydroxylase PF04116.8 EAQ87376.1 - 0.5 10.7 12.9 4.6 7.6 5.4 3.2 2 2 1 3 3 3 0 Fatty acid hydroxylase superfamily Catalase PF00199.14 EAQ87377.1 - 3.9e-127 424.1 0.2 3.4e-82 276.1 0.0 3.0 1 1 2 3 3 3 3 Catalase Catalase-rel PF06628.7 EAQ87377.1 - 0.059 13.2 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Catalase-related immune-responsive Methyltransf_33 PF10017.4 EAQ87378.1 - 6e-27 94.0 0.0 9.4e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Glyco_hydro_43 PF04616.9 EAQ87379.1 - 1.5e-36 125.9 0.8 1.1e-24 86.9 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 COesterase PF00135.23 EAQ87380.1 - 4.9e-89 299.4 0.0 7.1e-89 298.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ87380.1 - 1.6e-06 27.8 0.1 3.9e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.18 EAQ87381.1 - 0.063 12.9 0.1 0.087 12.5 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2852 PF11014.3 EAQ87382.1 - 0.0017 18.2 1.0 0.07 13.0 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2852) ADH_zinc_N PF00107.21 EAQ87383.1 - 6.5e-29 100.1 1.4 1.3e-28 99.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ87383.1 - 2.1e-17 64.2 0.3 5.3e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ87383.1 - 5.5e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EAQ87384.1 - 8.5e-43 146.4 0.0 1.1e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EAQ87384.1 - 5.7e-25 87.0 0.0 9.8e-25 86.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EAQ87384.1 - 3.1e-14 52.3 0.1 7.1e-14 51.1 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EAQ87384.1 - 2.3e-12 46.4 0.0 4.3e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EAQ87384.1 - 1.1e-11 44.1 0.0 1.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EAQ87384.1 - 2.6e-10 40.4 0.0 4.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EAQ87384.1 - 1.9e-08 33.5 0.0 1.1e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EAQ87384.1 - 5e-08 33.1 0.0 8.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EAQ87384.1 - 3.8e-07 29.9 0.0 7.9e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EAQ87384.1 - 0.012 14.9 0.0 0.057 12.6 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EAQ87384.1 - 0.018 14.4 0.2 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EAQ87384.1 - 0.04 12.8 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_18 PF12847.2 EAQ87384.1 - 0.05 14.1 0.0 4.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Sad1_UNC PF07738.8 EAQ87385.1 - 7.3e-10 38.7 0.0 0.0004 20.1 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal LMBR1 PF04791.11 EAQ87385.1 - 2.7 6.4 7.7 5.3 5.5 5.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DEAD PF00270.24 EAQ87386.1 - 4.8e-43 146.5 0.0 9e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EAQ87386.1 - 4.6e-24 83.7 0.2 9.8e-24 82.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EAQ87386.1 - 9.5e-21 73.4 0.0 1.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EAQ87386.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain DUF836 PF05768.9 EAQ87386.1 - 0.23 11.7 1.0 14 6.0 0.1 3.2 4 0 0 4 4 4 0 Glutaredoxin-like domain (DUF836) SR-25 PF10500.4 EAQ87386.1 - 4.1 6.8 23.8 0.097 12.1 2.0 4.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Transp_cyt_pur PF02133.10 EAQ87387.1 - 4.1e-148 493.5 34.3 4.7e-148 493.3 23.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4389 PF14333.1 EAQ87388.1 - 1.2 8.8 7.7 0.23 11.1 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) DDE_1 PF03184.14 EAQ87389.1 - 7.5e-37 126.5 0.0 1.5e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ87389.1 - 2.3e-10 40.1 0.0 6e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ87389.1 - 5.6e-09 35.4 0.0 1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ87389.1 - 1.1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF948 PF06103.6 EAQ87389.1 - 0.15 11.9 1.2 0.36 10.7 0.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EAQ87389.1 - 0.61 8.4 7.1 0.99 7.7 4.9 1.2 1 0 0 1 1 1 0 AAA domain YlqD PF11068.3 EAQ87389.1 - 0.7 9.9 7.9 1.4 8.9 5.5 1.4 1 0 0 1 1 1 0 YlqD protein OPT PF03169.10 EAQ87390.1 - 3.1e-96 323.2 35.2 2.5e-57 194.7 14.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DIE2_ALG10 PF04922.7 EAQ87391.1 - 4.8e-48 164.0 19.1 2.9e-47 161.5 13.2 2.0 1 1 0 1 1 1 1 DIE2/ALG10 family DUF2360 PF10152.4 EAQ87391.1 - 8.4 6.6 8.2 0.41 10.9 0.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) QCR10 PF09796.4 EAQ87392.1 - 6e-26 89.8 0.3 7.6e-26 89.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Med4 PF10018.4 EAQ87393.1 - 1.4e-58 197.4 8.6 1.8e-58 197.0 5.9 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 EMP70 PF02990.11 EAQ87395.1 - 2.4e-193 643.3 1.5 3e-193 643.0 1.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 EAQ87395.1 - 0.017 15.2 0.0 0.017 15.2 0.0 4.4 4 1 0 5 5 5 0 NfeD-like C-terminal, partner-binding PIRT PF15099.1 EAQ87395.1 - 0.13 11.5 1.2 0.3 10.2 0.8 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.10 EAQ87396.1 - 3.8e-16 59.0 1.3 7e-16 58.1 0.9 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pyr_redox_3 PF13738.1 EAQ87397.1 - 2.5e-19 70.1 0.0 1.7e-18 67.4 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ87397.1 - 3.2e-16 58.6 0.0 2.3e-15 55.7 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAQ87397.1 - 1.1e-10 41.7 0.0 0.00015 21.7 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ87397.1 - 2.3e-08 33.3 0.0 3.7e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAQ87397.1 - 1.3e-07 31.4 0.6 2.1e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAQ87397.1 - 9.1e-07 29.1 2.3 0.015 15.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ87397.1 - 1.3e-06 27.6 0.0 4.8e-06 25.7 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EAQ87397.1 - 4.7e-06 26.7 0.1 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EAQ87397.1 - 0.00069 19.3 0.1 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EAQ87397.1 - 0.0063 16.2 4.3 0.074 12.8 0.3 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EAQ87397.1 - 0.01 16.0 0.0 0.8 10.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EAQ87397.1 - 0.041 12.3 1.5 0.18 10.2 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EAQ87397.1 - 0.13 11.0 2.9 0.14 10.9 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain PDDEXK_1 PF12705.2 EAQ87397.1 - 0.26 10.6 0.6 0.74 9.1 0.4 1.6 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily GIDA PF01134.17 EAQ87397.1 - 0.27 10.0 2.2 0.35 9.6 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Phytase PF02333.10 EAQ87398.1 - 1.6e-24 86.3 0.0 7.7e-23 80.8 0.0 2.7 2 1 1 3 3 3 1 Phytase EGF_2 PF07974.8 EAQ87398.1 - 1.4e-06 28.3 39.7 0.0032 17.5 10.4 2.6 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 EAQ87398.1 - 0.00099 19.0 24.3 0.0049 16.7 4.0 2.5 2 0 0 2 2 2 2 EGF-like domain RicinB_lectin_2 PF14200.1 EAQ87398.1 - 0.049 13.9 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Chitin_bind_1 PF00187.14 EAQ87399.1 - 6e-09 35.7 12.2 6e-09 35.7 8.4 2.5 2 0 0 2 2 2 1 Chitin recognition protein Flavi_NS1 PF00948.16 EAQ87399.1 - 0.21 9.9 1.9 0.27 9.5 1.3 1.1 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 2-Hacid_dh_C PF02826.14 EAQ87400.1 - 1.3e-47 161.2 0.0 2.1e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DcpS_C PF11969.3 EAQ87400.1 - 2.6e-18 66.3 0.5 4.6e-18 65.5 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EAQ87400.1 - 5.7e-06 26.7 0.2 1.5e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 HIT domain F420_oxidored PF03807.12 EAQ87400.1 - 0.0034 17.7 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh PF00389.25 EAQ87400.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MFS_1 PF07690.11 EAQ87401.1 - 6.1e-23 81.0 23.3 9.9e-23 80.4 16.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ87401.1 - 2.2e-06 26.5 11.9 2.2e-06 26.5 8.3 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ87401.1 - 9.7e-05 20.7 6.6 0.00013 20.3 4.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EAQ87401.1 - 0.0006 18.4 10.5 0.0018 16.8 5.5 2.1 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EAQ87401.1 - 0.06 11.4 2.1 0.076 11.1 1.4 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector zf-BED PF02892.10 EAQ87402.1 - 0.00026 20.6 0.4 0.00076 19.1 0.3 1.9 1 0 0 1 1 1 1 BED zinc finger DUF4174 PF13778.1 EAQ87402.1 - 0.026 14.6 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) DUF1660 PF07874.6 EAQ87402.1 - 0.14 12.4 0.8 3.6 7.9 0.1 2.7 2 0 0 2 2 2 0 Prophage protein (DUF1660) Abhydrolase_3 PF07859.8 EAQ87403.1 - 6.4e-17 61.8 0.1 1.7e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EAQ87403.1 - 0.0047 15.7 0.0 0.0087 14.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF1996 PF09362.5 EAQ87405.1 - 4.1e-89 298.2 0.7 5.4e-89 297.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) KGG PF10685.4 EAQ87406.1 - 4.7e-21 74.2 4.1 9.7e-12 44.5 0.2 2.1 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Amidoligase_2 PF12224.3 EAQ87407.1 - 4.2e-17 62.6 0.0 8e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Putative amidoligase enzyme DUF3931 PF13082.1 EAQ87407.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) zf-CCHC PF00098.18 EAQ87409.1 - 0.00028 20.6 3.7 0.00028 20.6 2.6 3.1 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.1 EAQ87409.1 - 1.8 8.2 10.3 0.34 10.6 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle DUF4066 PF13278.1 EAQ87410.1 - 6.8e-21 74.2 0.0 1.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ87410.1 - 5.5e-13 48.6 0.0 1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Dicty_CAR PF05462.6 EAQ87411.1 - 0.00016 20.6 2.3 0.00016 20.6 1.6 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EAQ87411.1 - 0.00029 20.4 2.0 0.00052 19.6 1.4 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EAQ87411.1 - 0.0047 16.0 1.9 0.0047 16.0 1.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srt PF10321.4 EAQ87411.1 - 0.029 13.1 4.0 0.048 12.4 2.8 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt 7tm_2 PF00002.19 EAQ87411.1 - 0.11 11.5 6.2 0.19 10.7 4.3 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Asp_Arg_Hydrox PF05118.10 EAQ87412.1 - 0.068 13.0 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase DUF3984 PF13136.1 EAQ87415.1 - 0.067 12.4 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) COesterase PF00135.23 EAQ87420.1 - 2.8e-79 267.2 0.0 4.2e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ87420.1 - 9.3e-13 48.2 0.0 2.9e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ87420.1 - 8.5e-07 28.4 0.1 1.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ87420.1 - 0.02 14.6 0.1 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-trcl PF13451.1 EAQ87420.1 - 0.051 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Probable zinc-binding domain RVT_2 PF07727.9 EAQ87421.1 - 3.1e-58 196.6 0.0 5.3e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ87421.1 - 2.3e-14 53.5 0.0 5e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ87421.1 - 0.0026 17.3 0.0 0.0073 15.9 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain F-box PF00646.28 EAQ87421.1 - 0.19 11.4 0.1 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 F-box domain DZR PF12773.2 EAQ87421.1 - 4.1 7.3 9.3 2.5 7.9 2.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon Tyrosinase PF00264.15 EAQ87422.1 - 4.5e-46 157.7 0.0 7.5e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_16 PF00722.16 EAQ87424.1 - 1.3e-17 63.7 0.9 4.7e-17 61.8 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EAQ87424.1 - 1.5e-05 23.3 6.8 0.0065 14.6 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.4 EAQ87424.1 - 0.0087 15.5 0.1 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) Abhydrolase_3 PF07859.8 EAQ87425.1 - 9.2e-24 84.1 0.0 6.5e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ87425.1 - 9e-12 44.6 0.0 1.8e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ87425.1 - 1.9e-10 40.6 0.0 5.4e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ87425.1 - 1.4e-08 34.9 0.6 3.6e-08 33.5 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAQ87425.1 - 0.00044 19.7 0.0 0.28 10.6 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase COesterase PF00135.23 EAQ87425.1 - 0.0022 16.7 0.1 0.005 15.6 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 EAQ87425.1 - 0.0052 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EAQ87425.1 - 0.013 14.3 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 EAQ87425.1 - 0.02 14.1 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EAQ87425.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2424 PF10340.4 EAQ87425.1 - 0.034 12.7 0.2 0.16 10.5 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S51 PF03575.12 EAQ87425.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 COesterase PF00135.23 EAQ87427.1 - 7.5e-93 312.0 0.0 1.7e-92 310.9 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ87427.1 - 1.4e-05 24.7 0.1 8.7e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pectinesterase PF01095.14 EAQ87429.1 - 4.8e-43 146.8 1.8 6.9e-43 146.3 1.2 1.1 1 0 0 1 1 1 1 Pectinesterase AA_permease PF00324.16 EAQ87430.1 - 5.1e-124 414.2 43.1 6.3e-124 413.9 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ87430.1 - 4e-32 111.2 48.1 4.9e-32 111.0 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3129 PF11327.3 EAQ87433.1 - 1e-68 230.8 11.5 1.3e-68 230.4 8.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) PBP PF01161.15 EAQ87434.1 - 1.6e-10 41.0 0.3 6.7e-10 38.9 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Het-C PF07217.6 EAQ87434.1 - 0.033 12.3 0.0 0.059 11.5 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AhpC-TSA PF00578.16 EAQ87435.1 - 1.4e-11 44.1 0.0 2.6e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.1 EAQ87435.1 - 0.00015 21.6 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 EAQ87435.1 - 0.00026 20.5 0.0 0.00037 20.0 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EAQ87435.1 - 0.0051 16.8 0.0 0.047 13.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like SbcCD_C PF13558.1 EAQ87437.1 - 7.4e-05 22.5 0.0 0.00026 20.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EAQ87437.1 - 0.056 12.6 0.2 0.077 12.2 0.2 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain V_ATPase_I PF01496.14 EAQ87437.1 - 5.4 4.7 21.1 0.29 8.9 4.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EAQ87437.1 - 7.7 5.5 10.3 20 4.2 0.1 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EAQ87437.1 - 9.3 5.7 39.7 0.028 14.0 7.9 3.2 2 1 0 2 2 2 0 IncA protein CRAL_TRIO PF00650.15 EAQ87438.1 - 7.4e-23 80.7 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAQ87438.1 - 9.4e-12 44.8 0.1 2.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Coatomer_WDAD PF04053.9 EAQ87439.1 - 1.8e-171 570.8 0.0 7.5e-170 565.4 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EAQ87439.1 - 2.7e-46 153.8 4.6 9.8e-10 37.9 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EAQ87439.1 - 1.7e-06 26.4 3.4 0.018 13.2 1.5 4.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EAQ87439.1 - 0.00034 20.3 0.0 0.4 10.4 0.0 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Ribosomal_60s PF00428.14 EAQ87439.1 - 0.0018 18.5 12.8 0.0055 17.0 8.9 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein NOA36 PF06524.7 EAQ87439.1 - 1.6 7.9 6.3 2.3 7.3 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EAQ87439.1 - 4.9 6.6 15.6 9 5.8 10.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Mannitol_dh_C PF08125.8 EAQ87440.1 - 9.7e-46 155.9 0.0 1.3e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EAQ87440.1 - 1e-19 71.0 0.6 2.5e-19 69.6 0.1 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 EAQ87440.1 - 0.0009 18.6 0.3 0.0019 17.5 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EAQ87440.1 - 0.17 11.4 1.2 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EAQ87442.1 - 2.6e-10 39.8 0.0 3.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAQ87442.1 - 0.00026 20.8 2.3 0.00035 20.3 0.2 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAQ87442.1 - 0.0004 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ87442.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NPFF PF15085.1 EAQ87443.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Neuropeptide FF p450 PF00067.17 EAQ87444.1 - 2.1e-39 135.3 0.0 4.2e-28 98.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EAQ87445.1 - 9.4e-24 83.7 45.2 3.2e-18 65.5 20.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily GHMP_kinases_C PF08544.8 EAQ87445.1 - 0.083 13.0 0.4 0.82 9.9 0.1 2.4 2 0 0 2 2 2 0 GHMP kinases C terminal DUF349 PF03993.7 EAQ87446.1 - 0.059 13.5 0.8 0.14 12.3 0.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) F-112 PF09645.5 EAQ87446.1 - 0.065 13.1 0.6 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 F-112 protein Nucleoside_tran PF01733.13 EAQ87446.1 - 0.07 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter Abhydrolase_6 PF12697.2 EAQ87447.1 - 3.6e-16 59.7 0.0 4.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87447.1 - 2e-11 43.8 0.0 3.6e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EAQ87447.1 - 5.4e-08 32.5 0.0 7.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EAQ87447.1 - 2.6e-07 30.1 0.0 0.00014 21.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EAQ87447.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EAQ87447.1 - 0.00022 20.5 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 EAQ87447.1 - 0.00092 17.7 0.0 0.012 14.1 0.0 2.3 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EAQ87447.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EAQ87447.1 - 0.0086 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EAQ87447.1 - 0.029 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.6 EAQ87447.1 - 0.071 11.6 0.0 0.17 10.4 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) ADH_zinc_N PF00107.21 EAQ87448.1 - 2e-08 33.8 0.0 3.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ87448.1 - 1.8e-06 27.6 2.9 3.2e-06 26.8 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 EAQ87449.1 - 3.9e-76 255.9 0.0 8.2e-76 254.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ87449.1 - 4.9e-47 160.8 0.2 9.5e-47 159.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAQ87449.1 - 1.3e-45 155.8 4.2 3.9e-45 154.2 2.9 1.9 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EAQ87449.1 - 7.9e-33 113.6 0.1 2.6e-26 92.3 0.0 2.7 1 1 1 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.17 EAQ87449.1 - 4.9e-31 107.0 0.1 2.3e-30 104.8 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EAQ87449.1 - 1.3e-26 93.4 0.2 1.4e-21 77.1 0.0 3.1 1 1 1 2 2 2 2 short chain dehydrogenase Methyltransf_12 PF08242.7 EAQ87449.1 - 1.3e-14 54.4 0.0 3.6e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ87449.1 - 2e-11 44.2 0.0 5.8e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ87449.1 - 6.8e-10 38.7 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ87449.1 - 1.1e-09 38.2 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ87449.1 - 3e-09 37.4 0.0 1.9e-08 34.8 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ87449.1 - 9.3e-05 22.6 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EAQ87449.1 - 0.00035 19.6 0.0 0.00068 18.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EAQ87449.1 - 0.00077 18.6 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3669 PF12417.3 EAQ87451.1 - 8.9e-13 47.7 0.6 1.4e-11 43.9 0.0 2.6 3 0 0 3 3 3 1 Zinc finger protein MULE PF10551.4 EAQ87453.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 MULE transposase domain Helitron_like_N PF14214.1 EAQ87454.1 - 1.8e-32 112.5 8.9 3.8e-32 111.5 2.0 2.3 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus KNOX2 PF03791.8 EAQ87455.1 - 0.051 12.8 0.2 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 KNOX2 domain Dimer_Tnp_hAT PF05699.9 EAQ87457.1 - 1e-12 47.4 0.1 1.1e-11 44.1 0.1 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TMEM154 PF15102.1 EAQ87460.1 - 0.022 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Granulin PF00396.13 EAQ87460.1 - 0.066 13.3 5.1 0.1 12.7 0.9 2.6 2 0 0 2 2 2 0 Granulin Mpv17_PMP22 PF04117.7 EAQ87461.1 - 3e-23 81.2 0.6 1.7e-22 78.7 0.1 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 EAQ87462.1 - 1.6e-143 477.9 0.5 1.9e-143 477.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 EAQ87462.1 - 0.026 14.7 3.8 2 8.7 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain DUF3530 PF12048.3 EAQ87462.1 - 0.055 12.4 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.8 EAQ87463.1 - 3.9e-25 87.4 13.8 3.9e-25 87.4 9.6 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family DUF4348 PF14254.1 EAQ87463.1 - 0.8 8.7 3.3 1.1 8.3 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) zf-nanos PF05741.8 EAQ87464.1 - 0.19 11.7 1.6 0.36 10.8 1.1 1.5 1 1 0 1 1 1 0 Nanos RNA binding domain DUF3808 PF10300.4 EAQ87465.1 - 4.7e-128 427.6 0.0 6.7e-128 427.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 EAQ87465.1 - 0.025 14.4 2.4 0.13 12.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ87465.1 - 0.18 12.1 0.1 0.18 12.1 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TMV_coat PF00721.16 EAQ87465.1 - 0.55 10.1 2.7 2 8.3 0.0 2.8 3 0 0 3 3 3 0 Virus coat protein (TMV like) TPR_16 PF13432.1 EAQ87465.1 - 4.2 8.1 13.5 0.71 10.6 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat FA_hydroxylase PF04116.8 EAQ87466.1 - 5.2e-05 23.6 5.8 5.2e-05 23.6 4.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_6 PF12697.2 EAQ87467.1 - 1.3e-19 71.0 0.3 1.3e-19 71.0 0.2 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87467.1 - 6.1e-09 35.7 0.0 0.0022 17.7 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87467.1 - 1.6e-06 27.8 0.0 5.5e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_18 PF12847.2 EAQ87468.1 - 4.7e-07 30.3 0.0 7.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ87468.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ87468.1 - 5.6e-05 23.5 0.0 9.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ87468.1 - 6.2e-05 22.4 0.0 7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EAQ87468.1 - 0.00025 20.8 0.0 0.00026 20.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ87468.1 - 0.00052 20.4 0.0 0.0009 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EAQ87468.1 - 0.0012 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.15 EAQ87468.1 - 0.0051 15.8 0.0 0.0053 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 EAQ87468.1 - 0.0064 15.2 0.0 0.0082 14.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.1 EAQ87468.1 - 0.0075 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EAQ87468.1 - 0.013 14.3 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 EAQ87468.1 - 0.015 14.4 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EAQ87468.1 - 0.064 12.6 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EAQ87468.1 - 0.068 12.8 0.0 0.092 12.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ87468.1 - 0.088 12.8 0.1 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.6 EAQ87468.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Mito_carr PF00153.22 EAQ87470.1 - 5.3e-28 96.5 10.7 1.7e-18 66.1 0.4 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein PrpF PF04303.8 EAQ87471.1 - 1.8e-58 198.0 0.0 3.2e-52 177.4 0.0 2.3 2 0 0 2 2 2 2 PrpF protein Fungal_trans PF04082.13 EAQ87471.1 - 5e-25 87.8 0.1 7.4e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EAQ87472.1 - 2.5e-116 388.9 25.9 2.8e-116 388.7 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ87472.1 - 3.2e-25 88.6 52.8 1.3e-21 76.7 10.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_23 PF13489.1 EAQ87473.1 - 1.3e-09 37.9 0.0 4.3e-09 36.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ87473.1 - 0.027 14.0 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ87473.1 - 0.12 12.9 0.0 2.3 8.8 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain UNC-93 PF05978.11 EAQ87476.1 - 0.0024 17.3 1.4 0.0058 16.1 1.0 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 HA PF03457.9 EAQ87477.1 - 0.043 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain DHO_dh PF01180.16 EAQ87478.1 - 8.9e-61 205.4 0.0 2.9e-60 203.7 0.0 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EAQ87478.1 - 0.0027 16.9 1.2 1.7 7.8 0.1 2.4 2 0 0 2 2 2 2 PcrB family Vma12 PF11712.3 EAQ87478.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_hydro_61 PF03443.9 EAQ87479.1 - 5.2e-31 108.1 0.0 1.7e-29 103.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.14 EAQ87480.1 - 1.1e-07 31.2 0.1 3.5e-06 26.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain TerY-C PF15616.1 EAQ87480.1 - 0.72 9.7 2.4 1.3 8.9 1.7 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain COesterase PF00135.23 EAQ87481.1 - 5.1e-60 203.6 0.1 6.2e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ87481.1 - 3.1e-09 36.7 0.1 3.8e-08 33.1 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold DZR PF12773.2 EAQ87483.1 - 0.0001 22.0 9.5 0.0045 16.7 1.8 2.8 1 1 2 3 3 3 3 Double zinc ribbon zf-NADH-PPase PF09297.6 EAQ87483.1 - 0.0035 16.8 1.3 0.0035 16.8 0.9 4.1 3 2 1 4 4 4 2 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EAQ87483.1 - 0.0036 16.9 8.9 0.38 10.4 0.1 3.5 3 1 1 4 4 4 2 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.1 EAQ87483.1 - 0.15 12.3 4.3 0.49 10.7 3.0 1.7 1 1 0 1 1 1 0 Cytochrome c3 PADR1 PF08063.7 EAQ87483.1 - 1.2 8.5 9.1 0.81 9.1 0.1 2.6 2 1 1 3 3 3 0 PADR1 (NUC008) domain DNA_RNApol_7kD PF03604.8 EAQ87483.1 - 4.1 6.9 5.9 3 7.3 0.1 2.6 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-dskA_traR PF01258.12 EAQ87483.1 - 7.7 6.3 11.1 3.3 7.5 1.1 3.4 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger DUF1272 PF06906.6 EAQ87483.1 - 8.2 6.3 9.6 3.2 7.6 0.5 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1272) LysM PF01476.15 EAQ87484.1 - 3.7e-08 33.1 0.0 6.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain p450 PF00067.17 EAQ87485.1 - 8.3e-60 202.6 0.0 1.1e-59 202.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.16 EAQ87486.1 - 1.1e-57 194.9 0.1 2.1e-57 194.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Prok-E2_B PF14461.1 EAQ87486.1 - 0.098 12.4 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic E2 family B Palm_thioest PF02089.10 EAQ87488.1 - 6e-32 110.7 0.1 4.2e-28 98.0 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Lipase_2 PF01674.13 EAQ87488.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) zf-MYND PF01753.13 EAQ87489.1 - 0.0014 18.4 9.6 0.0024 17.6 6.7 1.4 1 0 0 1 1 1 1 MYND finger adh_short PF00106.20 EAQ87490.1 - 7.4e-12 45.5 0.6 9.1e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase Epiglycanin_C PF14654.1 EAQ87491.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2621 PF11084.3 EAQ87491.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Kua-UEV1_localn PF10520.4 EAQ87492.1 - 0.099 12.2 3.0 0.32 10.6 2.3 1.7 2 0 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF4106 PF13388.1 EAQ87492.1 - 0.24 10.3 3.9 0.28 10.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SelP_N PF04592.9 EAQ87492.1 - 3.4 6.9 8.6 4.3 6.6 6.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RVT_1 PF00078.22 EAQ87496.1 - 1.1e-13 50.9 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.18 EAQ87497.1 - 1.1e-06 28.5 0.0 7.4e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAQ87497.1 - 2e-06 27.0 0.0 3.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EAQ87497.1 - 1.7e-05 23.9 0.0 0.036 13.1 0.0 2.4 2 0 0 2 2 2 2 AIG1 family AAA_29 PF13555.1 EAQ87497.1 - 0.0013 18.2 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Swi5 PF07061.6 EAQ87497.1 - 0.0015 18.2 0.0 0.0057 16.4 0.0 2.0 1 0 0 1 1 1 1 Swi5 Septin PF00735.13 EAQ87497.1 - 0.0029 16.6 0.0 0.0096 14.9 0.0 1.9 1 1 0 1 1 1 1 Septin AAA_23 PF13476.1 EAQ87497.1 - 0.0058 16.9 0.3 0.14 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ87497.1 - 0.007 16.3 0.0 0.047 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAQ87497.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EAQ87497.1 - 0.023 14.5 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 EAQ87497.1 - 0.025 14.8 0.1 0.31 11.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EAQ87497.1 - 0.027 13.8 0.1 0.16 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA-like domain T2SE PF00437.15 EAQ87497.1 - 0.032 13.1 0.0 0.074 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EAQ87497.1 - 0.13 11.9 1.4 0.34 10.5 0.0 2.3 3 0 0 3 3 3 0 Archaeal ATPase RVT_1 PF00078.22 EAQ87501.1 - 1.3e-32 112.9 0.0 2.5e-32 111.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EAQ87501.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 RNase H OTT_1508_deam PF14441.1 EAQ87503.1 - 2.1e-11 43.8 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF2360 PF10152.4 EAQ87503.1 - 0.2 11.9 1.3 3.4 7.9 0.3 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SNO PF01174.14 EAQ87504.1 - 2e-53 180.8 0.0 1e-52 178.5 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EAQ87504.1 - 1.9e-10 40.5 0.1 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EAQ87504.1 - 0.00016 21.1 0.2 0.0068 15.8 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 EAQ87504.1 - 0.00068 18.9 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ87504.1 - 0.00077 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EAQ87504.1 - 0.0021 17.8 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.8 EAQ87504.1 - 0.08 12.3 0.5 0.71 9.2 0.0 2.7 3 1 0 3 3 3 0 Peptidase C26 Sin_N PF04801.8 EAQ87506.1 - 3.2e-08 32.8 0.0 5.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 EAQ87508.1 - 2.4e-176 588.4 43.9 2.5e-91 307.2 0.0 2.0 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EAQ87509.1 - 5.8e-142 472.5 7.1 7e-142 472.2 4.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 EAQ87510.1 - 7.7e-36 122.1 0.1 9e-36 121.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.19 EAQ87511.1 - 4.3e-42 143.7 4.5 6.6e-42 143.1 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAQ87511.1 - 2.4e-28 98.9 0.3 8e-28 97.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAQ87511.1 - 1.1e-16 61.3 0.9 1.8e-16 60.6 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ87511.1 - 4.7e-16 58.0 0.0 8.6e-16 57.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.3 EAQ87511.1 - 0.00094 18.6 0.1 0.0043 16.4 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CCT PF06203.9 EAQ87511.1 - 0.17 11.5 0.2 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 CCT motif Pkinase PF00069.20 EAQ87512.1 - 6.7e-62 208.9 0.0 1.4e-61 207.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87512.1 - 1.3e-35 122.6 0.0 2.6e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EAQ87512.1 - 1.3e-25 88.8 24.8 1.2e-15 56.9 3.5 2.8 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 EAQ87512.1 - 1.3e-20 72.8 26.7 5.9e-12 45.1 6.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EAQ87512.1 - 1.9e-14 53.9 2.2 5.3e-14 52.4 1.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAQ87512.1 - 0.015 14.2 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like She9_MDM33 PF05546.6 EAQ87513.1 - 2.9e-19 69.4 1.4 5.2e-13 49.0 0.3 2.2 2 0 0 2 2 2 2 She9 / Mdm33 family PAT1 PF09770.4 EAQ87513.1 - 9.7 4.2 24.3 13 3.8 16.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HAD PF12710.2 EAQ87515.1 - 3.1e-15 56.8 0.0 4.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ87515.1 - 8e-05 22.9 0.0 0.00021 21.5 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EAQ87515.1 - 0.00026 20.2 0.0 0.0065 15.6 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.7 EAQ87515.1 - 0.0015 17.8 0.0 0.0025 17.1 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) eIF-1a PF01176.14 EAQ87516.1 - 3.4e-15 55.1 0.0 5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DAO PF01266.19 EAQ87518.1 - 1.1e-19 70.6 1.8 1.5e-19 70.1 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PIF1 PF05970.9 EAQ87519.1 - 3.7e-05 22.8 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ87519.1 - 0.0017 18.4 0.0 0.0042 17.2 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ87519.1 - 0.0034 15.2 0.0 0.0047 14.7 0.0 1.1 1 0 0 1 1 1 1 Helicase HTH_20 PF12840.2 EAQ87519.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PIF1 PF05970.9 EAQ87520.1 - 0.051 12.5 0.2 0.085 11.7 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Thioredoxin PF00085.15 EAQ87521.1 - 4.5e-21 74.4 0.0 7.2e-21 73.8 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAQ87521.1 - 3.3e-05 24.0 0.0 5.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.6 EAQ87521.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 EAQ87521.1 - 0.053 13.6 0.0 3 8.0 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like WSC PF01822.14 EAQ87522.1 - 6.2e-23 80.5 8.7 1.1e-22 79.6 6.1 1.5 1 0 0 1 1 1 1 WSC domain DcpS_C PF11969.3 EAQ87523.1 - 1.2e-12 48.1 5.1 2.1e-11 44.0 3.5 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EAQ87523.1 - 1.4e-12 48.0 0.1 2.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 HIT domain NACHT PF05729.7 EAQ87525.1 - 6.9e-06 25.8 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Mannosyl_trans3 PF11051.3 EAQ87526.1 - 1.8e-30 106.2 3.1 1.6e-29 103.1 2.2 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Nuf2 PF03800.9 EAQ87529.1 - 3.5e-45 153.5 0.7 2.2e-44 150.9 0.0 2.5 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EAQ87529.1 - 2.6 7.1 11.3 2.4 7.2 2.4 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Adaptin_N PF01602.15 EAQ87530.1 - 1e-88 298.0 0.8 1.6e-86 290.7 0.3 2.0 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 EAQ87530.1 - 7.1e-12 45.4 1.1 1.2e-05 25.4 0.0 3.8 3 0 0 3 3 3 3 HEAT repeats HEAT PF02985.17 EAQ87530.1 - 1.6e-09 36.9 0.1 0.046 13.8 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EAQ87530.1 - 8.4e-07 29.2 4.4 0.0013 19.1 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EAQ87530.1 - 0.0054 16.6 0.2 0.61 10.1 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EAQ87530.1 - 0.0089 15.8 0.6 0.13 12.0 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Nop14 PF04147.7 EAQ87530.1 - 0.018 12.9 20.1 0.029 12.2 14.0 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EAQ87530.1 - 0.47 9.6 22.4 0.9 8.7 15.5 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EAQ87530.1 - 2.1 7.3 19.3 3.8 6.4 13.3 1.4 1 0 0 1 1 1 0 BUD22 DDHD PF02862.12 EAQ87530.1 - 3.7 7.2 7.2 7.7 6.2 5.0 1.5 1 0 0 1 1 1 0 DDHD domain Daxx PF03344.10 EAQ87530.1 - 4.2 5.7 26.1 6.6 5.0 18.1 1.2 1 0 0 1 1 1 0 Daxx Family NACHT PF05729.7 EAQ87531.1 - 3.5e-12 46.2 0.0 7.3e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ87531.1 - 1.8e-05 24.8 0.0 3.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EAQ87531.1 - 0.00049 19.1 0.0 0.46 9.4 0.0 2.1 1 1 1 2 2 2 2 KAP family P-loop domain AAA_29 PF13555.1 EAQ87531.1 - 0.0086 15.5 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EAQ87531.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EAQ87531.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ87531.1 - 0.024 14.9 0.1 0.045 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ87531.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EAQ87531.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase APS_kinase PF01583.15 EAQ87531.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Ank_2 PF12796.2 EAQ87533.1 - 1.4e-24 86.2 0.0 7.5e-11 42.2 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ87533.1 - 2.3e-22 78.9 0.5 4.6e-07 30.1 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ87533.1 - 3.9e-22 76.9 10.0 5e-06 26.0 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EAQ87533.1 - 9.7e-19 65.6 0.1 0.00058 19.8 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EAQ87533.1 - 1.2e-17 63.4 5.8 0.00065 19.8 0.2 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) FA PF08736.6 EAQ87533.1 - 0.031 14.0 0.5 3.5 7.4 0.0 2.7 3 0 0 3 3 3 0 FERM adjacent (FA) SH3_9 PF14604.1 EAQ87534.1 - 4.8e-06 26.0 0.0 9.7e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ87534.1 - 0.00011 21.5 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ87534.1 - 0.007 15.8 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain zf-C2H2_4 PF13894.1 EAQ87534.1 - 0.18 12.2 9.7 14 6.2 0.5 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger SapA PF02199.10 EAQ87538.1 - 0.0085 15.8 2.6 0.013 15.2 1.3 1.6 2 0 0 2 2 2 1 Saposin A-type domain Metallophos PF00149.23 EAQ87539.1 - 1.3e-37 129.1 0.2 1.5e-37 128.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 EAQ87540.1 - 5e-48 163.1 0.3 5.1e-47 159.8 0.0 2.0 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor PBP1_TM PF14812.1 EAQ87541.1 - 0.19 12.0 0.2 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_2 PF03446.10 EAQ87542.1 - 7.6e-36 123.4 0.0 1.2e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EAQ87542.1 - 2.6e-32 111.4 0.2 5.6e-32 110.3 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EAQ87542.1 - 4e-07 29.1 0.0 6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EAQ87542.1 - 7.8e-07 29.4 0.1 2.7e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EAQ87542.1 - 0.0001 22.8 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EAQ87542.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAQ87542.1 - 0.0032 17.4 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EAQ87542.1 - 0.03 13.9 0.1 0.12 12.0 0.1 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RTA1 PF04479.8 EAQ87543.1 - 8.7e-34 116.9 0.5 1.3e-33 116.3 0.4 1.2 1 0 0 1 1 1 1 RTA1 like protein RhoGEF PF00621.15 EAQ87545.1 - 5.7e-26 91.4 0.7 1.3e-25 90.3 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 EAQ87545.1 - 0.037 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) DUF1451 PF07295.6 EAQ87545.1 - 0.32 10.7 4.3 0.28 10.9 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) DUF3584 PF12128.3 EAQ87545.1 - 1.4 6.1 13.0 3.5 4.8 9.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Xpo1 PF08389.7 EAQ87546.1 - 0.0048 16.8 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Exportin 1-like protein GRIP PF01465.15 EAQ87546.1 - 0.037 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 GRIP domain PI31_Prot_N PF11566.3 EAQ87547.1 - 1e-24 86.8 0.0 1.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EAQ87547.1 - 5.1e-18 65.4 27.0 5.1e-18 65.4 18.7 3.8 3 2 0 3 3 3 1 PI31 proteasome regulator DUF2036 PF09724.4 EAQ87549.1 - 1e-08 34.7 0.0 1.2e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IBR PF01485.16 EAQ87550.1 - 4.1e-07 29.7 28.3 0.00022 21.0 4.4 3.5 3 0 0 3 3 3 2 IBR domain BHD_3 PF10405.4 EAQ87551.1 - 1.5e-25 88.7 0.0 2.9e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EAQ87551.1 - 2.3e-19 68.6 0.1 4.2e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EAQ87551.1 - 1.6e-17 63.5 0.2 1.6e-17 63.5 0.2 4.3 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.10 EAQ87551.1 - 5.1e-11 42.1 0.1 5.2e-08 32.4 0.0 2.9 1 1 1 2 2 2 2 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EAQ87551.1 - 0.0069 16.5 0.0 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily CDC45 PF02724.9 EAQ87551.1 - 1.9 6.4 5.0 5.4 4.9 3.5 1.7 1 0 0 1 1 1 0 CDC45-like protein zf-AN1 PF01428.11 EAQ87552.1 - 2.2e-25 88.2 17.9 2.5e-13 49.6 4.2 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EAQ87552.1 - 0.0036 17.1 12.4 0.19 11.6 2.4 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 EAQ87552.1 - 0.015 15.4 14.6 0.59 10.3 3.8 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.7 EAQ87552.1 - 4.1 7.4 16.3 13 5.8 5.5 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain FhuF_C PF11575.3 EAQ87552.1 - 8.5 6.1 9.6 11 5.7 0.1 4.0 4 0 0 4 4 4 0 FhuF 2Fe-2S C-terminal domain MTP18 PF10558.4 EAQ87553.1 - 6.3e-41 139.7 0.1 8.4e-41 139.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EAQ87554.1 - 6.4e-26 90.2 0.2 7.3e-26 90.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) PsbJ PF01788.12 EAQ87554.1 - 0.53 9.8 3.3 0.8 9.2 2.3 1.4 1 0 0 1 1 1 0 PsbJ Filament_head PF04732.9 EAQ87556.1 - 2 9.1 4.8 1.5 9.5 0.2 2.3 2 1 0 3 3 3 0 Intermediate filament head (DNA binding) region Vps36_ESCRT-II PF11605.3 EAQ87558.1 - 9.9e-27 92.5 0.0 1.5e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EAQ87558.1 - 6e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 EAQ87558.1 - 0.00033 20.1 5.2 0.003 17.0 0.2 2.8 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EAQ87558.1 - 0.0016 17.4 11.4 0.0071 15.4 0.4 2.8 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EAQ87558.1 - 0.1 12.4 0.4 0.1 12.4 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 EAQ87558.1 - 5.6 6.7 6.7 33 4.2 0.1 3.6 3 1 1 4 4 4 0 PHD-finger SAC3_GANP PF03399.11 EAQ87559.1 - 1.8e-68 230.1 0.6 2.3e-68 229.7 0.4 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EAQ87559.1 - 0.0062 16.3 0.2 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 EAQ87560.1 - 4.7e-25 86.7 0.0 2e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EAQ87560.1 - 3.1e-15 55.4 0.2 3e-07 29.9 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EAQ87560.1 - 4.6e-15 55.4 0.0 8.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EAQ87560.1 - 1.1e-11 43.9 0.0 2.1e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EAQ87560.1 - 2.4e-09 36.7 0.0 4.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain HTH_Tnp_Tc5 PF03221.11 EAQ87561.1 - 1.1e-17 63.5 2.7 8e-17 60.8 0.3 3.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 EAQ87561.1 - 1.3 9.1 6.2 0.26 11.4 0.2 2.7 2 1 1 3 3 3 0 Winged helix-turn helix DUF3716 PF12511.3 EAQ87562.1 - 2.3e-34 116.7 12.9 4.5e-17 61.3 2.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) CoA_binding_2 PF13380.1 EAQ87564.1 - 4.8e-27 94.4 0.0 6.1e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EAQ87564.1 - 0.0029 18.0 0.0 0.0043 17.5 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain DUF1425 PF07233.7 EAQ87564.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) EF-hand_7 PF13499.1 EAQ87565.1 - 9.9e-13 48.0 0.1 4.6e-10 39.4 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 EAQ87565.1 - 3.6e-11 42.8 0.0 2e-05 24.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 EAQ87565.1 - 7.8e-09 34.6 0.5 0.01 15.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EAQ87565.1 - 1.8e-08 33.8 0.6 0.00025 20.6 0.1 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EAQ87565.1 - 2e-07 29.8 0.8 0.011 15.0 0.0 4.1 4 1 0 4 4 4 2 EF hand UPF0154 PF03672.8 EAQ87565.1 - 0.033 13.8 0.0 0.095 12.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EAQ87565.1 - 0.32 10.4 2.8 2 7.8 0.7 3.0 3 0 0 3 3 3 0 EF hand Peptidase_M3 PF01432.15 EAQ87566.1 - 4.7e-158 526.9 0.0 5.9e-158 526.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EAQ87566.1 - 0.005 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Effector protein Aa_trans PF01490.13 EAQ87567.1 - 1.1e-61 208.5 37.9 1.3e-61 208.3 26.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein BIR PF00653.16 EAQ87568.1 - 4.7e-33 113.4 4.7 5.9e-17 61.8 0.4 3.1 3 1 0 3 3 3 2 Inhibitor of Apoptosis domain DUF1996 PF09362.5 EAQ87569.1 - 3.9e-25 88.9 0.0 6.9e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pmp3 PF01679.12 EAQ87569.1 - 1.4e-17 63.1 0.4 2.2e-17 62.4 0.3 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Mmp37 PF09139.6 EAQ87570.1 - 1.1e-136 455.2 0.0 1.5e-136 454.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAD PF05557.8 EAQ87571.1 - 3.3e-52 177.5 49.1 4.2e-52 177.2 34.0 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein BRE1 PF08647.6 EAQ87571.1 - 0.0051 16.7 6.8 0.0051 16.7 4.7 6.1 3 1 4 7 7 7 1 BRE1 E3 ubiquitin ligase muHD PF10291.4 EAQ87572.1 - 3.2e-80 269.0 0.0 4.9e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EAQ87572.1 - 1.9e-11 43.9 1.3 1.7e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain IZUMO PF15005.1 EAQ87572.1 - 2 8.4 3.5 1.4 8.9 1.1 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion Pkinase PF00069.20 EAQ87573.1 - 1.7e-12 47.0 0.0 1.2e-08 34.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain GATase PF00117.23 EAQ87574.1 - 1e-28 100.1 0.0 2e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EAQ87574.1 - 2e-08 33.8 0.1 6.9e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EAQ87574.1 - 2.4e-07 29.9 0.1 8.1e-07 28.1 0.1 1.8 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.11 EAQ87574.1 - 0.00054 18.6 0.1 0.0008 18.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EAQ87574.1 - 0.00062 19.2 0.0 0.00098 18.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Peptidase_C26 PF07722.8 EAQ87574.1 - 0.00071 19.0 0.1 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 Asn_synthase PF00733.16 EAQ87574.1 - 0.0077 15.7 0.1 0.017 14.6 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase ATP_bind_3 PF01171.15 EAQ87574.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.14 EAQ87574.1 - 0.039 12.9 0.1 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 EAQ87574.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 EAQ87574.1 - 0.13 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF2501 PF10696.4 EAQ87574.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) Fungal_trans_2 PF11951.3 EAQ87575.1 - 3.7e-17 62.0 0.3 5.3e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ87575.1 - 2.7e-08 33.5 8.3 5.7e-08 32.5 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidoligase_2 PF12224.3 EAQ87576.1 - 6.6e-09 35.7 0.0 2.3e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Putative amidoligase enzyme WD40 PF00400.27 EAQ87577.1 - 4.7e-32 108.7 2.4 6.7e-12 44.8 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 EAQ87577.1 - 2.2e-13 50.1 0.1 4.1e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ87577.1 - 4.4e-05 23.5 0.3 0.00049 20.1 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Nup160 PF11715.3 EAQ87577.1 - 0.00047 18.4 1.0 0.091 10.8 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 EAQ87577.1 - 0.0014 17.8 0.3 4.4 6.7 0.0 3.7 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EAQ87577.1 - 0.0097 14.6 0.2 0.11 11.1 0.1 2.0 1 1 0 1 1 1 1 Nup133 N terminal like PD40 PF07676.7 EAQ87577.1 - 0.015 14.9 0.3 19 5.0 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 EAQ87577.1 - 0.055 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EAQ87577.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EAQ87577.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 EAQ87577.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EAQ87579.1 - 0.0008 19.1 8.9 1.2 9.1 0.5 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat GTP1_OBG PF01018.17 EAQ87579.1 - 0.45 10.1 7.2 0.78 9.3 5.0 1.3 1 0 0 1 1 1 0 GTP1/OBG Mito_fiss_reg PF05308.6 EAQ87579.1 - 3.1 7.0 13.5 5.4 6.2 9.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PQ-loop PF04193.9 EAQ87580.1 - 1.4e-23 82.2 17.1 1.6e-12 46.7 1.8 3.0 3 0 0 3 3 3 2 PQ loop repeat DUF1345 PF07077.6 EAQ87580.1 - 0.0057 16.2 3.8 0.18 11.3 1.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1345) DUF4153 PF13687.1 EAQ87580.1 - 0.0061 16.1 5.3 0.0061 16.1 3.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4153) DUF3796 PF12676.2 EAQ87580.1 - 0.076 13.2 0.1 0.076 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF1129 PF06570.6 EAQ87580.1 - 0.2 10.9 1.7 0.43 9.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Pox_A14 PF05767.7 EAQ87580.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF3814 PF12769.2 EAQ87580.1 - 0.58 10.3 5.6 5 7.3 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3814) DUF4131 PF13567.1 EAQ87580.1 - 2.9 7.2 14.4 0.4 10.0 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) R3H-assoc PF13902.1 EAQ87581.1 - 5.8e-27 94.2 2.4 5.8e-27 94.2 1.7 1.9 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 EAQ87581.1 - 0.0025 17.4 0.0 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 R3H domain Rieske PF00355.21 EAQ87583.1 - 1.7e-17 62.7 0.0 2.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EAQ87583.1 - 1.9e-11 44.0 0.1 4.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region MMS1_N PF10433.4 EAQ87584.1 - 2.1e-105 352.7 0.0 2.8e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EAQ87584.1 - 1.1e-53 182.3 0.0 5.6e-29 101.2 0.0 3.3 3 0 0 3 3 3 3 CPSF A subunit region zf-trcl PF13451.1 EAQ87585.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Probable zinc-binding domain HTH_31 PF13560.1 EAQ87585.1 - 0.049 13.8 4.6 0.15 12.2 0.7 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DJ-1_PfpI PF01965.19 EAQ87586.1 - 5.9e-27 93.9 1.5 2.8e-26 91.7 1.1 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EAQ87586.1 - 6.7e-21 73.5 0.2 1.6e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EAQ87586.1 - 0.012 14.8 0.0 0.034 13.4 0.0 1.8 2 1 0 2 2 2 0 Putative amidotransferase Mucin PF01456.12 EAQ87587.1 - 0.19 11.4 23.3 0.029 14.1 10.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Pex14_N PF04695.8 EAQ87587.1 - 0.28 11.2 8.3 4.4 7.3 0.8 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cellulase PF00150.13 EAQ87588.1 - 2.4e-24 86.0 0.3 3.1e-24 85.6 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EAQ87588.1 - 0.00021 21.6 0.0 0.00046 20.5 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EAQ87588.1 - 0.00039 19.4 0.0 0.0012 17.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EAQ87588.1 - 0.0021 17.2 0.8 0.0067 15.5 0.1 2.0 3 0 0 3 3 3 1 Beta-galactosidase zf-C2H2_4 PF13894.1 EAQ87590.1 - 4.2e-06 26.7 7.6 0.0062 16.7 0.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-ribbon_3 PF13248.1 EAQ87590.1 - 0.016 14.3 0.8 4.3 6.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EAQ87590.1 - 0.022 15.0 0.6 0.022 15.0 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ87590.1 - 0.025 14.9 14.9 0.086 13.2 1.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 EAQ87590.1 - 0.047 13.9 4.3 2.5 8.4 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 EAQ87590.1 - 0.15 12.0 3.8 0.53 10.3 0.1 2.7 2 0 0 2 2 2 0 zinc-finger zf-C2H2_jaz PF12171.3 EAQ87590.1 - 0.6 10.3 2.4 22 5.3 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.20 EAQ87592.1 - 6.8e-13 48.3 0.0 1.6e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87592.1 - 4.5e-05 22.6 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 EAQ87594.1 - 2.8e-05 23.2 0.2 3.9e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4448 PF14610.1 EAQ87594.1 - 0.16 11.4 2.0 7.7 5.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Gly_transf_sug PF04488.10 EAQ87596.1 - 6.6e-12 45.7 0.1 1.6e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF1510 PF07423.6 EAQ87596.1 - 0.001 18.4 17.5 0.001 18.4 12.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 EAQ87596.1 - 0.14 12.0 10.5 0.21 11.5 7.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.8 EAQ87596.1 - 1.4 8.3 6.6 2 7.8 4.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Daxx PF03344.10 EAQ87596.1 - 3.6 5.9 18.4 4.7 5.5 12.8 1.1 1 0 0 1 1 1 0 Daxx Family Adeno_VII PF03228.9 EAQ87596.1 - 3.7 8.1 9.9 4.1 8.0 5.8 1.8 2 0 0 2 2 2 0 Adenoviral core protein VII CT47 PF15623.1 EAQ87596.1 - 5.1 6.7 24.6 7.2 6.2 17.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 U79_P34 PF03064.11 EAQ87596.1 - 6.5 6.1 17.6 9.3 5.6 12.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.7 EAQ87596.1 - 7.3 6.3 20.6 10 5.9 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Oxidored_FMN PF00724.15 EAQ87598.1 - 2e-73 247.3 0.0 2.4e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SNF2_N PF00176.18 EAQ87599.1 - 4.1e-17 61.9 0.0 1.9e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain HIRAN PF08797.6 EAQ87599.1 - 0.00064 19.6 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 2 HIRAN domain DEAD PF00270.24 EAQ87599.1 - 0.032 13.7 0.0 6.3 6.2 0.0 4.0 4 2 0 4 4 4 0 DEAD/DEAH box helicase TelA PF05816.6 EAQ87599.1 - 0.073 11.7 2.5 4.8 5.7 0.1 2.4 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Tobravirus_2B PF05271.6 EAQ87599.1 - 0.12 12.0 0.0 22 4.7 0.0 2.3 2 0 0 2 2 2 0 Tobravirus 2B protein DUF4535 PF15054.1 EAQ87599.1 - 0.26 10.6 6.3 4.5 6.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) RICH PF05062.7 EAQ87599.1 - 0.42 10.7 7.0 7.3 6.7 0.5 2.5 2 0 0 2 2 2 0 RICH domain SNF2_N PF00176.18 EAQ87602.1 - 1.8e-30 105.7 0.0 2.6e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ87602.1 - 1.3e-10 40.9 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EAQ87602.1 - 5.2e-06 26.0 3.3 1.6e-05 24.5 2.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAQ87602.1 - 0.00083 19.3 1.4 0.00083 19.3 1.0 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ87602.1 - 0.0051 16.6 4.2 0.0051 16.6 2.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EAQ87602.1 - 0.025 14.2 3.4 0.09 12.4 2.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ87602.1 - 0.032 13.8 6.9 0.092 12.4 4.0 2.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ87602.1 - 1.3 8.9 6.2 0.17 11.8 1.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING HET PF06985.6 EAQ87603.1 - 3.8e-25 88.6 0.0 7.2e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.21 EAQ87604.1 - 3.3e-05 23.9 23.4 0.0014 18.8 0.7 5.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ87604.1 - 4.2e-05 23.6 1.5 4.2e-05 23.6 1.0 6.5 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ87604.1 - 0.00011 22.2 7.4 0.002 18.3 1.2 6.8 7 0 0 7 7 7 2 C2H2-type zinc finger zf-met PF12874.2 EAQ87604.1 - 0.00036 20.6 9.1 0.04 14.1 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAQ87604.1 - 0.00092 19.2 9.9 0.11 12.7 0.4 4.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EAQ87604.1 - 0.14 12.0 3.1 5.8 6.9 0.1 3.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.7 EAQ87604.1 - 5.9 7.0 6.9 1.7 8.8 1.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MFS_2 PF13347.1 EAQ87605.1 - 0.0067 14.8 0.1 0.0092 14.4 0.1 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein DUF641 PF04859.7 EAQ87605.1 - 0.0092 15.7 2.1 0.014 15.1 1.5 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Virul_fac_BrkB PF03631.10 EAQ87605.1 - 0.02 14.2 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Virulence factor BrkB PIRT PF15099.1 EAQ87605.1 - 0.027 13.6 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family UPF0093 PF03653.8 EAQ87605.1 - 0.032 14.2 0.2 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) FixQ PF05545.6 EAQ87605.1 - 0.16 11.6 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ FtsX PF02687.16 EAQ87605.1 - 2.5 7.8 4.9 0.22 11.2 0.2 1.6 2 0 0 2 2 2 0 FtsX-like permease family CorA PF01544.13 EAQ87605.1 - 2.7 6.9 7.1 5.7 5.8 3.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ATP-synt_B PF00430.13 EAQ87605.1 - 5 6.9 9.4 16 5.2 4.2 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Pkinase PF00069.20 EAQ87607.1 - 6.5e-14 51.7 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87607.1 - 2.2e-05 23.6 0.0 9.6e-05 21.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase zf-CCHC_4 PF14392.1 EAQ87608.1 - 0.038 13.6 6.7 0.18 11.4 0.9 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EAQ87608.1 - 0.071 12.7 1.7 0.27 10.9 1.2 2.0 1 0 0 1 1 1 0 Zinc knuckle CAP59_mtransfer PF11735.3 EAQ87609.1 - 3.7e-67 226.0 0.0 1e-66 224.6 0.0 1.6 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RdRP PF05183.7 EAQ87610.1 - 3.8e-113 379.2 0.1 6.3e-113 378.4 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_11 PF13086.1 EAQ87610.1 - 1.1e-45 156.0 3.3 6.2e-44 150.3 2.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ87610.1 - 8.1e-12 44.7 0.1 2.4e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAQ87610.1 - 9.4e-12 44.9 0.0 5.3e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EAQ87610.1 - 1.5e-10 40.7 0.0 3.7e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EAQ87610.1 - 0.00091 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EAQ87610.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EAQ87610.1 - 0.0049 16.2 0.0 0.027 13.7 0.0 1.9 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EAQ87610.1 - 0.0092 15.2 0.0 0.076 12.2 0.0 2.5 2 1 0 2 2 2 1 PhoH-like protein AAA PF00004.24 EAQ87610.1 - 0.01 16.0 0.0 0.035 14.3 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ87610.1 - 0.041 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EAQ87610.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 EAQ87610.1 - 0.12 12.5 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EAQ87611.1 - 6.3e-12 45.7 0.0 2.5e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ87611.1 - 0.0018 18.2 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 EAQ87611.1 - 0.051 12.1 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Peripla_BP_3 PF13377.1 EAQ87611.1 - 0.1 12.6 1.5 0.14 12.1 0.6 1.5 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Septin PF00735.13 EAQ87611.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_14 PF13173.1 EAQ87611.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain HSP70 PF00012.15 EAQ87613.1 - 0.0059 14.5 0.1 0.0089 13.9 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein Bac_luciferase PF00296.15 EAQ87613.1 - 0.19 10.8 1.6 1.2 8.2 1.1 2.0 1 1 0 1 1 1 0 Luciferase-like monooxygenase HD_3 PF13023.1 EAQ87614.1 - 9.2e-47 158.8 0.0 1.2e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 HD domain DUF3433 PF11915.3 EAQ87616.1 - 3.1e-33 113.7 15.0 5.2e-20 71.4 1.6 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Glyco_hydro_75 PF07335.6 EAQ87617.1 - 6.3e-12 45.6 0.0 1.7e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 Nucleoporin_C PF03177.9 EAQ87619.1 - 3.3e-144 481.6 3.2 4.3e-144 481.2 2.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EAQ87619.1 - 1.5e-94 317.1 0.3 2e-94 316.7 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 EAQ87620.1 - 1.5e-23 83.5 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ87620.1 - 1.9e-14 54.0 0.0 2.6e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ87620.1 - 1.4e-08 34.6 0.0 2.7e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAQ87620.1 - 0.0012 18.9 0.1 0.0024 17.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Erg28 PF03694.8 EAQ87621.1 - 2e-46 156.5 0.2 2.4e-46 156.3 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein YrhK PF14145.1 EAQ87621.1 - 1.1 9.0 3.8 3.4 7.4 0.0 2.8 2 1 1 3 3 3 0 YrhK-like protein GalP_UDP_transf PF01087.17 EAQ87622.1 - 5.9e-73 244.8 1.0 1.5e-71 240.2 0.3 2.4 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EAQ87622.1 - 1.2e-55 187.5 0.0 2.4e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EAQ87622.1 - 0.0019 18.6 0.0 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 HIT domain SWIRM PF04433.12 EAQ87623.1 - 5.5e-14 52.0 0.0 1.8e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EAQ87623.1 - 8.6e-07 28.9 0.0 2.8e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SHOCT PF09851.4 EAQ87623.1 - 0.013 14.9 0.5 0.058 12.8 0.4 2.2 1 0 0 1 1 1 0 Short C-terminal domain adh_short PF00106.20 EAQ87624.1 - 2.3e-06 27.6 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Mg_trans_NIPA PF05653.9 EAQ87625.1 - 4.4e-90 301.6 22.5 6.3e-90 301.1 15.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EAQ87625.1 - 5.9e-08 32.8 6.1 5.9e-08 32.8 4.2 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EAQ87625.1 - 2.2e-05 24.4 7.6 2.2e-05 24.4 5.3 2.8 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EAQ87625.1 - 0.00061 18.7 3.3 0.00061 18.7 2.3 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) MIP-T3 PF10243.4 EAQ87625.1 - 0.11 10.9 4.6 0.17 10.3 3.2 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U-box PF04564.10 EAQ87626.1 - 1.1e-19 70.0 0.0 2.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EAQ87626.1 - 1.9e-18 65.8 7.6 1.5e-14 53.3 0.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAQ87626.1 - 8.1e-10 37.8 3.6 0.066 13.1 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ87626.1 - 3e-06 27.0 1.2 8.6e-06 25.5 0.8 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ87626.1 - 3.9e-06 26.2 0.3 0.4 10.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ87626.1 - 5.5e-06 26.9 0.2 5.5e-06 26.9 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ87626.1 - 2.9e-05 23.9 1.0 0.021 14.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ87626.1 - 0.0018 18.5 1.6 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ87626.1 - 0.0052 17.3 12.0 0.23 12.1 0.0 4.2 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ87626.1 - 0.0058 16.5 8.3 0.043 13.7 2.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87626.1 - 4.9 7.1 7.1 10 6.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.1 EAQ87628.1 - 1.1e-08 34.4 0.0 1.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ87628.1 - 3.5e-05 23.1 0.0 5.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ87628.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.13 EAQ87628.1 - 0.0063 16.2 1.2 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Glycophorin A Mid2 PF04478.7 EAQ87628.1 - 0.0085 15.5 0.1 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 EAQ87628.1 - 0.016 13.5 0.2 0.054 11.7 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 EAQ87628.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Plasmodium_Vir PF05795.6 EAQ87628.1 - 0.028 13.6 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rifin_STEVOR PF02009.11 EAQ87628.1 - 0.068 12.7 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Yip1 PF04893.12 EAQ87628.1 - 0.085 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain IncA PF04156.9 EAQ87628.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 IncA protein Amnionless PF14828.1 EAQ87628.1 - 0.23 9.8 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF202 PF02656.10 EAQ87628.1 - 0.23 11.6 0.9 0.52 10.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Gar1 PF04410.9 EAQ87630.1 - 1.2e-50 170.9 0.4 1.2e-50 170.9 0.3 2.5 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 EAQ87631.1 - 2.5e-87 293.6 20.0 2.9e-87 293.3 13.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F-box-like PF12937.2 EAQ87632.1 - 1.8e-08 33.9 0.2 0.0027 17.4 0.0 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EAQ87632.1 - 7.5e-05 22.2 0.1 0.19 11.4 0.0 2.7 2 0 0 2 2 2 2 F-box domain RNA_pol_Rpb2_5 PF04567.12 EAQ87632.1 - 0.021 14.7 1.5 0.079 12.9 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 Exo5 PF09810.4 EAQ87633.1 - 3.9e-123 410.8 0.0 6.2e-123 410.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EAQ87633.1 - 7.2e-05 22.2 1.1 0.0058 16.0 0.8 3.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily tRNA-synt_2b PF00587.20 EAQ87634.1 - 9.4e-22 77.4 0.1 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EAQ87634.1 - 1.2e-20 73.1 0.3 2.5e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EAQ87634.1 - 4.3e-15 55.4 0.0 9.6e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_S49_N PF08496.5 EAQ87634.1 - 8.4 6.1 6.8 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cpn60_TCP1 PF00118.19 EAQ87635.1 - 2.7e-143 478.1 12.2 3.1e-143 477.9 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GspL_C PF12693.2 EAQ87635.1 - 0.17 11.6 0.7 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 GspL periplasmic domain Acetyltransf_7 PF13508.1 EAQ87636.1 - 2.9e-06 27.3 0.0 1.2e-05 25.4 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ87636.1 - 0.00024 21.0 0.5 0.00091 19.2 0.3 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EAQ87636.1 - 0.0036 17.1 0.2 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ87636.1 - 0.0082 15.8 0.0 0.033 13.9 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EAQ87636.1 - 0.034 14.0 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AFG1_ATPase PF03969.11 EAQ87638.1 - 2.3e-96 322.7 0.0 1.4e-91 307.0 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EAQ87638.1 - 1.2e-05 25.3 2.0 0.012 15.6 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EAQ87638.1 - 0.00067 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EAQ87638.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ87638.1 - 0.0071 16.4 0.2 0.03 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EAQ87638.1 - 0.008 16.3 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EAQ87638.1 - 0.015 15.2 0.0 0.11 12.5 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EAQ87638.1 - 0.048 13.3 0.0 0.19 11.3 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.13 EAQ87638.1 - 0.049 13.2 0.3 0.68 9.5 0.0 2.8 3 1 0 3 3 3 0 Bacterial dnaA protein RNA_helicase PF00910.17 EAQ87638.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Peptidase_M28 PF04389.12 EAQ87639.1 - 2.1e-24 86.2 0.1 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAQ87639.1 - 4.2e-05 23.1 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PLDc_2 PF13091.1 EAQ87640.1 - 1.4e-16 60.3 0.0 5.3e-07 29.4 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EAQ87640.1 - 0.0093 15.7 0.1 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EAQ87640.1 - 0.18 10.7 0.0 3.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB SKG6 PF08693.5 EAQ87641.1 - 5.9 6.2 7.3 0.65 9.3 1.8 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF605 PF04652.11 EAQ87642.1 - 0.92 8.8 12.0 1.1 8.6 8.3 1.1 1 0 0 1 1 1 0 Vta1 like NUC153 PF08159.7 EAQ87643.1 - 2.5e-13 49.3 0.4 2.5e-13 49.3 0.3 2.8 3 0 0 3 3 3 1 NUC153 domain Hamartin PF04388.7 EAQ87643.1 - 1.6 7.2 8.6 3 6.4 6.0 1.4 1 0 0 1 1 1 0 Hamartin protein TTL PF03133.10 EAQ87644.1 - 1.1e-18 67.2 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Glyco_hydro_62 PF03664.8 EAQ87645.1 - 4.1e-140 465.5 11.1 5e-140 465.2 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 EAQ87645.1 - 3.4e-13 49.0 12.7 7.3e-13 47.9 8.8 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.8 EAQ87646.1 - 4.6e-65 219.4 0.5 5.7e-65 219.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 EAQ87646.1 - 1.6e-13 50.0 12.7 3.4e-13 48.9 8.8 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain zf-C2HC_2 PF13913.1 EAQ87648.1 - 0.021 14.4 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Ifi-6-16 PF06140.8 EAQ87648.1 - 0.67 9.7 33.3 0.13 12.0 20.5 1.9 1 1 0 1 1 1 0 Interferon-induced 6-16 family Sporozoite_P67 PF05642.6 EAQ87648.1 - 5.2 4.8 10.2 6.7 4.4 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Methyltransf_26 PF13659.1 EAQ87649.1 - 5.8e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ87649.1 - 9.8e-07 29.1 0.0 2.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ87649.1 - 4e-06 26.1 0.0 6.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EAQ87649.1 - 0.00065 20.1 0.0 0.0016 18.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ87649.1 - 0.00079 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ87649.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ87649.1 - 0.11 13.0 0.0 0.32 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain FAR1 PF03101.10 EAQ87650.1 - 0.0053 17.2 0.2 0.011 16.2 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Cyt-b5 PF00173.23 EAQ87651.1 - 1.4e-12 47.2 0.2 5.4e-10 38.9 0.0 3.1 1 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1983 PF09327.6 EAQ87651.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1983) RVT_1 PF00078.22 EAQ87652.1 - 1.6e-26 92.9 0.0 3.2e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ87652.1 - 7.5e-19 67.9 1.4 2.5e-18 66.3 0.1 2.5 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.5 EAQ87652.1 - 4.5e-07 29.1 0.0 1.3e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Chromo PF00385.19 EAQ87652.1 - 1.6e-06 27.6 0.2 8.5e-06 25.3 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain FAD_binding_3 PF01494.14 EAQ87654.1 - 1.5e-18 66.9 0.4 8.1e-18 64.5 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.1 EAQ87654.1 - 2e-10 40.6 0.1 1.7e-09 37.6 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain NAD_binding_8 PF13450.1 EAQ87654.1 - 2.9e-08 33.6 0.1 7.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ87654.1 - 3.7e-06 26.0 0.1 0.00013 20.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Methyltransf_11 PF08241.7 EAQ87654.1 - 2e-05 24.9 0.0 8e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ87654.1 - 0.00016 22.2 0.0 0.0014 19.1 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain FAD_binding_2 PF00890.19 EAQ87654.1 - 0.0002 20.3 0.3 0.00041 19.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAQ87654.1 - 0.00027 21.0 0.0 0.0014 18.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ87654.1 - 0.00066 20.0 0.0 0.012 15.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ87654.1 - 0.0013 17.9 0.0 0.0077 15.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Methyltransf_12 PF08242.7 EAQ87654.1 - 0.0019 18.6 0.0 0.01 16.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.9 EAQ87654.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ87654.1 - 0.0033 15.9 0.1 0.0062 15.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EAQ87654.1 - 0.0041 16.1 0.1 0.5 9.2 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 EAQ87654.1 - 0.051 12.6 0.1 1.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EAQ87654.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EAQ87654.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EAQ87654.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EAQ87654.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EAQ87654.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ubie_methyltran PF01209.13 EAQ87654.1 - 0.22 10.6 0.0 1.7 7.6 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Med13_C PF06333.7 EAQ87654.1 - 0.47 8.9 4.9 0.69 8.3 3.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Prefoldin PF02996.12 EAQ87656.1 - 0.013 15.1 0.3 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit zf-PHD-like PF15446.1 EAQ87656.1 - 0.023 13.9 2.4 0.036 13.3 1.7 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain APG6 PF04111.7 EAQ87656.1 - 0.057 12.4 2.2 0.07 12.1 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 EAQ87656.1 - 0.25 10.6 2.2 0.38 10.1 1.6 1.2 1 0 0 1 1 1 0 fzo-like conserved region COG2 PF06148.6 EAQ87656.1 - 0.26 11.1 2.5 0.42 10.4 1.7 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2852 PF11014.3 EAQ87656.1 - 0.31 11.0 6.0 0.82 9.6 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) IncA PF04156.9 EAQ87656.1 - 0.41 10.2 4.6 0.63 9.5 3.2 1.2 1 0 0 1 1 1 0 IncA protein Zn_clus PF00172.13 EAQ87656.1 - 4.8 7.1 8.3 5 7.1 0.8 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Snf7 PF03357.16 EAQ87656.1 - 8 5.8 9.9 14 5.0 6.9 1.4 1 1 0 1 1 1 0 Snf7 Cyclin_N PF00134.18 EAQ87657.1 - 1.6e-08 34.1 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain NmrA PF05368.8 EAQ87658.1 - 2.8e-45 154.3 0.0 3.3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ87658.1 - 8.3e-09 35.6 0.3 1.9e-08 34.5 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 EAQ87658.1 - 0.0059 16.5 0.1 0.0099 15.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EAQ87658.1 - 0.038 13.4 0.2 0.077 12.4 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EAQ87658.1 - 0.082 12.5 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 EAQ87658.1 - 0.13 11.2 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase HAD_2 PF13419.1 EAQ87659.1 - 0.039 14.1 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mucin PF01456.12 EAQ87659.1 - 1.7 8.3 17.9 3.4 7.4 12.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.15 EAQ87660.1 - 3.8e-21 75.2 0.0 5.4e-20 71.4 0.0 2.3 2 1 0 2 2 2 1 Fructose-1-6-bisphosphatase TPR_19 PF14559.1 EAQ87662.1 - 0.029 14.6 0.0 1.2 9.5 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87662.1 - 0.042 13.4 0.0 1 9.0 0.0 2.8 2 0 0 2 2 2 0 TPR repeat Ribosomal_60s PF00428.14 EAQ87666.1 - 0.044 14.1 0.5 0.062 13.7 0.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein OpuAC PF04069.7 EAQ87666.1 - 0.073 12.4 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system RVT_1 PF00078.22 EAQ87667.1 - 9.4e-30 103.5 0.0 1.5e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ87667.1 - 3.9e-07 29.7 0.0 1.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Zn_Tnp_IS91 PF14319.1 EAQ87667.1 - 0.077 12.5 4.1 0.21 11.0 2.9 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC PF00098.18 EAQ87667.1 - 0.12 12.3 3.6 0.37 10.8 0.9 2.9 2 0 0 2 2 2 0 Zinc knuckle Brix PF04427.13 EAQ87668.1 - 8.7e-58 195.1 0.0 1.2e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain CENP-T PF15511.1 EAQ87668.1 - 0.043 13.0 12.6 0.074 12.2 8.7 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DEAD PF00270.24 EAQ87669.1 - 4.3e-48 162.9 0.0 6.9e-48 162.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ87669.1 - 3.5e-25 87.6 0.0 6.1e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ87669.1 - 0.00014 21.7 0.0 0.00058 19.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EAQ87669.1 - 0.04 13.6 0.4 0.19 11.4 0.0 2.3 2 1 0 2 2 2 0 Part of AAA domain CwfJ_C_2 PF04676.9 EAQ87670.1 - 5e-25 87.8 0.0 1.9e-24 86.0 0.0 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EAQ87670.1 - 6.2e-24 83.9 0.0 1.3e-23 82.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.4 EAQ87670.1 - 0.07 13.2 0.3 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Fumarase C C-terminus SASP PF00269.15 EAQ87671.1 - 0.074 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type Metaviral_G PF09595.5 EAQ87671.1 - 0.77 9.3 5.7 1.4 8.5 3.9 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein ATP_bind_1 PF03029.12 EAQ87672.1 - 2.1e-77 259.8 0.0 2.8e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EAQ87672.1 - 7.4e-06 25.5 0.0 0.002 17.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EAQ87672.1 - 2.6e-05 23.5 0.0 0.11 11.7 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAQ87672.1 - 3e-05 23.9 0.0 8.8e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EAQ87672.1 - 8e-05 21.5 0.1 0.016 13.9 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 EAQ87672.1 - 0.00046 20.3 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 EAQ87672.1 - 0.0011 18.3 0.0 1.5 8.1 0.0 2.7 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EAQ87672.1 - 0.0013 19.1 0.0 0.3 11.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EAQ87672.1 - 0.0024 17.1 0.0 0.11 11.7 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B NB-ARC PF00931.17 EAQ87672.1 - 0.0036 16.2 0.1 0.0066 15.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EAQ87672.1 - 0.0039 17.0 0.0 0.0039 17.0 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_10 PF12846.2 EAQ87672.1 - 0.0056 16.1 0.1 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EAQ87672.1 - 0.011 16.5 0.4 0.063 14.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain U1snRNP70_N PF12220.3 EAQ87672.1 - 0.012 15.8 0.3 0.032 14.5 0.2 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NACHT PF05729.7 EAQ87672.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.17 EAQ87672.1 - 0.018 14.5 0.0 0.068 12.6 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.5 EAQ87672.1 - 0.019 14.1 0.0 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.14 EAQ87672.1 - 0.025 14.0 0.0 0.84 9.0 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EAQ87672.1 - 0.025 14.1 0.1 0.064 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 EAQ87672.1 - 0.029 13.8 0.0 0.25 10.8 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 EAQ87672.1 - 0.032 13.7 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EAQ87672.1 - 0.072 13.3 0.7 2.8 8.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF258 PF03193.11 EAQ87672.1 - 0.085 12.0 3.2 1.1 8.3 0.0 3.4 3 2 1 4 4 4 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ87672.1 - 0.085 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 EAQ87672.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EAQ87672.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_RNApol_7kD PF03604.8 EAQ87673.1 - 2.4e-14 52.4 4.4 3.1e-14 52.1 3.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.9 EAQ87673.1 - 0.0011 18.8 0.4 0.34 10.8 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EAQ87673.1 - 0.011 15.5 0.5 0.017 14.9 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EAQ87673.1 - 0.015 14.9 0.5 0.02 14.5 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 EAQ87673.1 - 0.064 12.7 0.5 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 EAQ87673.1 - 0.12 12.1 0.5 0.18 11.5 0.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2197 PF09963.4 EAQ87673.1 - 0.12 12.3 1.4 2.2 8.2 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-NADH-PPase PF09297.6 EAQ87673.1 - 0.58 9.7 3.4 2.4 7.7 2.3 2.1 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EAQ87673.1 - 0.97 9.2 3.4 1.6 8.6 0.2 2.1 1 1 2 3 3 3 0 Transposase zinc-ribbon domain Aldo_ket_red PF00248.16 EAQ87674.1 - 3.9e-22 78.4 0.0 6.8e-22 77.6 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family ChAPs PF09295.5 EAQ87675.1 - 2.4e-162 540.2 0.0 3e-162 539.8 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EAQ87675.1 - 5.4e-07 29.6 0.3 0.43 11.3 0.3 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87675.1 - 0.00028 20.4 0.3 1.4 8.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ87675.1 - 0.00041 20.0 0.1 0.074 13.0 0.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87675.1 - 0.00051 19.6 0.9 0.56 9.9 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 EAQ87675.1 - 0.00074 19.1 0.0 1.5 8.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ87675.1 - 0.0061 16.3 0.1 5.8 6.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ87675.1 - 0.024 14.9 0.0 4.6 7.6 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ87675.1 - 0.039 13.5 0.1 7.9 6.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87676.1 - 0.0052 16.4 1.6 38 4.0 0.1 4.7 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EAQ87676.1 - 0.044 14.0 0.0 12 6.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat UQ_con PF00179.21 EAQ87677.1 - 2.4e-38 130.7 0.0 2.8e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ87677.1 - 0.0043 16.7 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAQ87677.1 - 0.033 14.0 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.13 EAQ87678.1 - 3.6e-33 114.8 0.2 6.1e-32 110.8 0.1 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Nop14 PF04147.7 EAQ87680.1 - 0.0059 14.5 12.5 0.0071 14.3 8.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EAQ87680.1 - 0.2 9.6 13.9 0.23 9.4 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 EAQ87680.1 - 0.43 9.2 3.3 0.4 9.3 2.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2890 PF11081.3 EAQ87680.1 - 2.1 8.3 22.4 3.7 7.5 15.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Spore_coat_CotO PF14153.1 EAQ87680.1 - 2.7 7.3 12.5 3.8 6.9 8.3 1.5 1 1 1 2 2 2 0 Spore coat protein CotO RRN3 PF05327.6 EAQ87680.1 - 2.9 5.8 4.2 3 5.8 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.7 EAQ87680.1 - 3.1 5.7 8.3 3.6 5.5 5.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HsbA PF12296.3 EAQ87682.1 - 5.7e-24 84.3 1.2 6.8e-24 84.0 0.8 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A COX1 PF00115.15 EAQ87683.1 - 0.0014 17.3 4.5 0.16 10.5 0.8 2.0 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I Frag1 PF10277.4 EAQ87683.1 - 0.026 14.0 0.5 0.026 14.0 0.3 1.5 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family Tetraspannin PF00335.15 EAQ87683.1 - 0.049 12.9 3.5 0.13 11.4 2.4 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF4231 PF14015.1 EAQ87683.1 - 0.14 12.1 2.5 4.1 7.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_S24 PF00717.18 EAQ87684.1 - 1.5e-07 30.9 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like AAA_22 PF13401.1 EAQ87685.1 - 3.6e-08 33.6 0.0 5.5e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ87685.1 - 2.4e-05 24.3 0.1 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EAQ87685.1 - 0.0011 18.4 0.3 0.035 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 EAQ87685.1 - 0.0029 17.2 0.9 0.018 14.6 0.6 2.5 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EAQ87685.1 - 0.005 17.0 0.1 0.072 13.2 0.0 2.6 3 0 0 3 3 3 1 RNA helicase Arch_ATPase PF01637.13 EAQ87685.1 - 0.0074 16.0 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EAQ87685.1 - 0.013 15.0 0.0 0.043 13.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EAQ87685.1 - 0.04 14.7 0.1 0.24 12.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EAQ87685.1 - 0.046 13.1 0.2 1.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EAQ87685.1 - 0.051 13.8 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EAQ87685.1 - 0.086 12.5 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EAQ87685.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ87685.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EAQ87685.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Trehalase PF01204.13 EAQ87685.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Trehalase BTB PF00651.26 EAQ87686.1 - 7.3e-07 29.1 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EAQ87686.1 - 0.14 12.3 0.0 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF1349 PF07081.6 EAQ87687.1 - 3.1e-13 49.4 0.0 8.6e-12 44.7 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1349) TFIIB PF00382.14 EAQ87688.1 - 6.6e-29 99.5 2.8 1.4e-14 53.6 0.3 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EAQ87688.1 - 1.9e-19 69.6 0.1 1.9e-19 69.6 0.0 2.4 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EAQ87688.1 - 0.0049 16.4 0.7 0.18 11.3 0.0 2.3 1 1 0 2 2 2 1 Cyclin, N-terminal domain Lipase_GDSL PF00657.17 EAQ87690.1 - 7.4e-18 65.2 0.2 4e-17 62.8 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAQ87690.1 - 6.5e-17 62.2 1.0 9.8e-17 61.6 0.7 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EAQ87690.1 - 2.7e-06 27.2 0.0 5.1e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GFA PF04828.9 EAQ87693.1 - 9.5e-22 76.7 0.2 1.5e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EAQ87693.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) E1-E2_ATPase PF00122.15 EAQ87694.1 - 9.7e-21 73.8 0.0 1.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ87694.1 - 1.1e-16 61.9 0.2 2.2e-12 47.8 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAQ87694.1 - 1.5e-11 44.8 0.0 2.3e-10 40.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ87694.1 - 5.2e-11 42.3 0.0 1.6e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAQ87694.1 - 0.0019 17.7 0.0 0.0087 15.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ87694.1 - 0.06 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Dynamin_N PF00350.18 EAQ87695.1 - 1.7e-20 73.5 0.2 1.8e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Dynamin family Dynamin_M PF01031.15 EAQ87695.1 - 1e-07 31.0 0.1 2.7e-06 26.3 0.0 2.7 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EAQ87695.1 - 0.0007 19.5 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EAQ87695.1 - 0.038 14.1 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain adh_short_C2 PF13561.1 EAQ87696.1 - 8.2e-33 114.1 0.7 1.6e-25 90.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ87696.1 - 1.3e-21 77.1 9.4 8.4e-11 42.0 1.2 2.5 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EAQ87696.1 - 2.9e-06 27.0 1.3 1.1e-05 25.1 0.3 2.0 2 0 0 2 2 2 1 KR domain YjeF_N PF03853.10 EAQ87696.1 - 0.0016 18.0 0.3 0.0031 17.1 0.2 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Virul_Fac PF10139.4 EAQ87696.1 - 0.033 12.1 0.0 0.045 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor THF_DHG_CYH_C PF02882.14 EAQ87696.1 - 0.045 12.8 0.7 0.11 11.6 0.5 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EAQ87696.1 - 0.072 12.9 1.4 0.17 11.6 0.9 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Vps35 PF03635.12 EAQ87697.1 - 0 1034.5 0.0 0 1034.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3915 PF13054.1 EAQ87697.1 - 0.25 11.2 1.8 0.38 10.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Vpu PF00558.14 EAQ87697.1 - 0.29 10.7 1.4 1 8.9 0.9 1.9 1 0 0 1 1 1 0 Vpu protein TFR_dimer PF04253.10 EAQ87698.1 - 2.1e-24 85.4 0.0 3.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EAQ87698.1 - 2e-12 47.1 0.0 7.4e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EAQ87698.1 - 3.8e-05 23.2 0.1 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 PA domain TENA_THI-4 PF03070.11 EAQ87699.1 - 2.8e-08 33.7 0.0 2.4e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 TENA/THI-4/PQQC family AAA PF00004.24 EAQ87699.1 - 0.0056 16.8 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CorA PF01544.13 EAQ87699.1 - 0.15 11.1 0.0 0.4 9.6 0.0 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pyr_redox_3 PF13738.1 EAQ87700.1 - 2e-17 63.9 0.0 4.7e-17 62.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAQ87700.1 - 4.8e-12 44.8 0.0 7.3e-12 44.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EAQ87700.1 - 4.1e-10 39.0 0.0 8.4e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Cadherin_C PF01049.12 EAQ87701.1 - 0.057 13.4 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic region Guanylate_kin PF00625.16 EAQ87702.1 - 1.2e-62 210.5 0.0 1.4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EAQ87702.1 - 1.7e-08 34.4 0.0 4.3e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ87702.1 - 5.9e-05 23.3 0.0 0.00017 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ87702.1 - 0.0003 20.9 0.1 0.0018 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ87702.1 - 0.0019 17.4 0.0 0.0039 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAQ87702.1 - 0.0023 18.7 0.1 0.0044 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ87702.1 - 0.0034 17.2 0.0 0.0072 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ87702.1 - 0.0078 16.2 0.1 0.016 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EAQ87702.1 - 0.011 15.7 0.3 0.62 10.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain DUF1895 PF08988.5 EAQ87702.1 - 0.016 15.2 0.3 0.029 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) ABC_tran PF00005.22 EAQ87702.1 - 0.022 15.0 0.0 0.028 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Tail_tube PF10618.4 EAQ87702.1 - 0.028 14.1 0.1 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein AAA_24 PF13479.1 EAQ87702.1 - 0.041 13.4 0.0 0.12 11.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EAQ87702.1 - 0.085 12.2 0.6 2.4 7.5 0.1 2.4 1 1 1 2 2 2 0 Thymidylate kinase Sugar_tr PF00083.19 EAQ87703.1 - 2.7e-70 237.2 18.2 3.2e-70 236.9 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ87703.1 - 7.9e-24 84.0 26.3 1.9e-19 69.5 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TBP PF00352.16 EAQ87704.1 - 1.8e-61 203.5 0.0 2.9e-30 103.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EAQ87704.1 - 0.00027 20.9 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) LELP1 PF15042.1 EAQ87705.1 - 0.0086 16.2 0.8 0.019 15.1 0.5 1.5 1 0 0 1 1 1 1 Late cornified envelope-like proline-rich protein 1 Bact_transglu_N PF08379.5 EAQ87705.1 - 0.045 14.0 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial transglutaminase-like N-terminal region UDPGT PF00201.13 EAQ87706.1 - 1e-06 27.6 0.0 1.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GMC_oxred_N PF00732.14 EAQ87707.1 - 5.3e-44 150.5 0.0 1.7e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ87707.1 - 4.9e-28 98.2 0.0 1e-27 97.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ87707.1 - 0.0014 17.5 0.0 0.0045 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ87707.1 - 0.0031 17.4 0.1 0.01 15.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ87707.1 - 0.01 14.7 0.1 0.028 13.3 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EAQ87707.1 - 0.018 13.6 0.0 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EAQ87707.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Methyltransf_32 PF13679.1 EAQ87707.1 - 0.1 12.2 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Thi4 PF01946.12 EAQ87707.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ricin_B_lectin PF00652.17 EAQ87708.1 - 8.5e-09 35.4 0.9 3.2e-08 33.6 0.6 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAQ87708.1 - 6.6e-07 29.6 0.5 1.3e-05 25.4 0.3 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_76 PF03663.9 EAQ87710.1 - 7.6e-114 380.9 0.4 1e-113 380.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EAQ87710.1 - 0.0001 21.4 2.1 0.0039 16.2 0.2 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 ACC_epsilon PF13822.1 EAQ87710.1 - 0.14 12.5 0.1 0.14 12.5 0.0 2.9 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit Gln-synt_C PF00120.19 EAQ87711.1 - 1.6e-60 204.4 0.0 1.9e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EAQ87711.1 - 2.2e-19 68.7 0.0 3.7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain APH PF01636.18 EAQ87712.1 - 1.5e-15 57.6 4.3 2.6e-15 56.8 3.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ87712.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase OB_NTP_bind PF07717.11 EAQ87713.1 - 5.4e-27 93.8 0.0 7.2e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAQ87713.1 - 2e-09 37.1 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pmp3 PF01679.12 EAQ87714.1 - 4.1e-20 71.2 5.0 5.3e-20 70.8 3.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.5 EAQ87715.1 - 2e-143 478.0 0.0 2.5e-143 477.7 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 EAQ87716.1 - 8.2e-54 182.2 0.0 2.6e-53 180.5 0.0 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase Clp1 PF06807.9 EAQ87717.1 - 4.9e-19 68.8 0.0 1.3e-18 67.4 0.0 1.6 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EAQ87717.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EAQ87717.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAQ87717.1 - 0.01 15.3 0.1 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EAQ87717.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ87717.1 - 0.14 12.4 0.1 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Git3 PF11710.3 EAQ87718.1 - 5.2e-66 222.0 15.8 1e-65 221.1 10.9 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EAQ87718.1 - 2.3e-30 104.1 2.8 5e-30 103.0 0.4 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EAQ87718.1 - 9.5e-08 31.4 3.6 9.8e-08 31.4 1.5 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GATase PF00117.23 EAQ87719.1 - 3.7e-12 46.1 0.0 4.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAQ87719.1 - 0.033 13.6 0.1 0.16 11.3 0.1 2.2 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 EAQ87719.1 - 0.052 13.1 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Oligomerisation PF02410.10 EAQ87720.1 - 0.00016 21.6 0.0 0.0034 17.3 0.0 2.3 1 1 0 1 1 1 1 Oligomerisation domain RNA_pol PF00940.14 EAQ87721.1 - 2.9e-165 549.6 0.0 4e-165 549.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EAQ87721.1 - 1.1e-80 271.3 3.8 1.1e-80 271.3 2.6 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.15 EAQ87722.1 - 1.1e-22 79.7 0.3 7.7e-22 76.9 0.2 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EAQ87722.1 - 9.9e-06 25.9 0.0 3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ87722.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ87722.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.18 EAQ87723.1 - 1.5e-66 224.2 0.5 2.6e-66 223.4 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ87723.1 - 2.8e-16 59.1 0.0 1.5e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ87723.1 - 3.2e-06 27.0 0.1 2.6e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAQ87723.1 - 0.065 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.1 EAQ87726.1 - 1e-50 172.0 2.0 2.6e-50 170.7 1.4 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ87726.1 - 1.6e-26 93.1 0.0 3e-22 79.0 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ87726.1 - 5e-06 26.2 0.0 3.4e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ87726.1 - 0.0013 18.8 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain XPA_N PF01286.13 EAQ87726.1 - 0.013 15.1 1.9 0.036 13.7 1.3 1.7 1 0 0 1 1 1 0 XPA protein N-terminal AAA_19 PF13245.1 EAQ87726.1 - 0.017 14.8 0.1 0.058 13.1 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 EAQ87726.1 - 0.12 12.2 0.0 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Torsin NMT_C PF02799.10 EAQ87726.1 - 0.21 10.9 0.8 0.88 8.9 0.1 2.1 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain WSC PF01822.14 EAQ87727.1 - 1.1e-15 57.3 7.0 2.3e-15 56.2 4.8 1.5 1 0 0 1 1 1 1 WSC domain PAS_3 PF08447.6 EAQ87728.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 PAS fold DUF2628 PF10947.3 EAQ87730.1 - 0.11 12.2 1.7 0.19 11.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) VIT1 PF01988.14 EAQ87730.1 - 1 8.7 6.2 1.6 8.1 4.3 1.2 1 0 0 1 1 1 0 VIT family PDGLE PF13190.1 EAQ87731.1 - 0.0083 15.7 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 PDGLE domain Plasmodium_Vir PF05795.6 EAQ87731.1 - 0.066 12.4 0.1 0.079 12.1 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pex14_N PF04695.8 EAQ87731.1 - 0.84 9.6 5.5 1.4 8.9 3.1 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_47 PF01532.15 EAQ87732.1 - 2.4e-166 553.8 0.0 2.8e-166 553.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EAQ87732.1 - 0.00034 19.0 0.0 0.022 13.0 0.0 2.4 2 1 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) zf-C2H2_4 PF13894.1 EAQ87733.1 - 0.00083 19.5 4.6 0.0026 17.9 3.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ87733.1 - 0.24 11.7 6.3 0.77 10.2 4.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EAQ87733.1 - 1 9.7 4.6 2.6 8.4 3.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF814 PF05670.8 EAQ87734.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DUF1180 PF06679.7 EAQ87734.1 - 6.7 6.5 5.7 0.71 9.7 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Alpha_kinase PF02816.13 EAQ87735.1 - 1.8e-38 132.1 0.0 2.2e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Stc1 PF12898.2 EAQ87735.1 - 0.031 14.3 1.9 0.053 13.5 1.3 1.3 1 0 0 1 1 1 0 Stc1 domain HAUS6_N PF14661.1 EAQ87736.1 - 1.2e-68 231.1 0.6 1.2e-68 231.1 0.4 2.6 2 1 1 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus PWI PF01480.12 EAQ87736.1 - 1e-09 38.3 0.5 2.2e-09 37.2 0.4 1.6 1 0 0 1 1 1 1 PWI domain Glyco_hydro_72 PF03198.9 EAQ87739.1 - 1e-118 395.9 4.1 1.4e-118 395.4 2.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EAQ87739.1 - 1.4e-06 27.7 0.4 7.7e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Bombesin PF02044.12 EAQ87739.1 - 6.4 6.3 7.4 15 5.1 1.1 2.4 2 0 0 2 2 2 0 Bombesin-like peptide Cytochrom_B561 PF03188.11 EAQ87741.1 - 4.4e-06 26.5 7.7 1.1e-05 25.2 5.4 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 YtpI PF14007.1 EAQ87741.1 - 0.09 12.7 1.1 0.26 11.2 0.7 1.9 1 1 0 1 1 1 0 YtpI-like protein DUF202 PF02656.10 EAQ87741.1 - 0.13 12.4 6.7 5.8 7.2 0.8 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF1517 PF07466.6 EAQ87741.1 - 0.14 11.1 1.8 0.24 10.3 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) NfeD PF01957.13 EAQ87741.1 - 1.1 9.3 9.2 0.17 12.0 1.3 2.4 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF2427 PF10348.4 EAQ87741.1 - 4.9 6.7 13.2 3.9 7.1 6.8 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2427) Pec_lyase_C PF00544.14 EAQ87742.1 - 4.2e-42 143.8 2.5 6.2e-42 143.3 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EAQ87742.1 - 0.007 16.1 6.8 0.13 12.0 4.7 2.2 1 1 0 1 1 1 1 Right handed beta helix region p450 PF00067.17 EAQ87743.1 - 2.4e-48 164.7 0.0 3.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 EAQ87744.1 - 3.1e-10 40.1 0.0 4.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ87744.1 - 6.6e-10 38.9 0.0 9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3956 PF13104.1 EAQ87745.1 - 0.24 11.0 1.2 0.56 9.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Jacalin PF01419.12 EAQ87746.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Abhydrolase_3 PF07859.8 EAQ87747.1 - 4.6e-22 78.6 1.4 6.1e-22 78.2 1.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ87747.1 - 2.7e-08 33.6 0.8 4.3e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ87747.1 - 3e-05 23.3 0.0 0.017 14.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EAQ87747.1 - 6.2e-05 21.8 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EAQ87747.1 - 0.00074 18.4 0.1 0.0011 17.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 EAQ87747.1 - 0.00086 17.8 0.0 0.49 8.8 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 EAQ87747.1 - 0.003 16.4 0.1 0.0043 15.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DUF2424 PF10340.4 EAQ87747.1 - 0.03 12.9 0.0 0.21 10.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Esterase PF00756.15 EAQ87747.1 - 0.11 11.8 0.1 0.77 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.2 EAQ87748.1 - 8e-20 71.6 1.9 9.5e-20 71.4 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87748.1 - 2.1e-09 37.2 1.3 3.9e-09 36.4 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87748.1 - 0.055 13.0 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EAQ87748.1 - 0.059 12.8 0.1 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 EAQ87750.1 - 9.5e-19 68.1 10.8 1.3e-18 67.7 7.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87750.1 - 3.7e-10 39.7 0.4 5.1e-10 39.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87750.1 - 1.4e-07 31.2 0.1 2.6e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EAQ87750.1 - 3.9e-06 26.4 0.1 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EAQ87750.1 - 6.6e-05 23.2 0.1 9.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF3141 PF11339.3 EAQ87750.1 - 0.038 12.3 0.9 0.048 11.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Hydrolase_4 PF12146.3 EAQ87750.1 - 0.083 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 EAQ87750.1 - 0.088 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.9 EAQ87751.1 - 3.7e-66 223.2 0.1 5.1e-66 222.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase DUF3614 PF12267.3 EAQ87752.1 - 0.11 12.8 0.1 0.15 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) A_amylase_inhib PF01356.14 EAQ87753.1 - 0.027 14.2 0.1 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha amylase inhibitor ABC_membrane PF00664.18 EAQ87755.1 - 2.4e-20 73.0 6.9 1e-14 54.5 0.1 4.2 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ87755.1 - 0.016 15.4 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CheY-binding PF09078.6 EAQ87755.1 - 0.22 11.5 0.2 0.48 10.4 0.1 1.5 1 0 0 1 1 1 0 CheY binding Polyketide_cyc2 PF10604.4 EAQ87757.1 - 1.3e-05 25.4 1.2 2e-05 24.7 0.8 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Lactamase_B_2 PF12706.2 EAQ87758.1 - 3.8e-39 134.2 0.0 4.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAQ87758.1 - 3.3e-10 39.8 0.0 5.7e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAQ87758.1 - 4.7e-06 26.3 0.1 3e-05 23.7 0.1 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PAS_9 PF13426.1 EAQ87759.1 - 5.4e-17 62.0 0.0 9.9e-15 54.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EAQ87759.1 - 0.0024 17.6 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold Glyco_hydro_92 PF07971.7 EAQ87760.1 - 4.9e-134 447.7 0.5 5.9e-104 348.4 0.0 3.0 1 1 2 3 3 3 3 Glycosyl hydrolase family 92 VGCC_alpha2 PF08473.6 EAQ87761.1 - 0.052 13.3 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd ERbeta_N PF12497.3 EAQ87761.1 - 9.9 6.0 9.2 1.1 9.1 2.9 2.0 2 0 0 2 2 2 0 Estrogen receptor beta Pyridox_oxidase PF01243.15 EAQ87762.1 - 2e-07 30.8 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.15 EAQ87763.1 - 4.1e-19 69.1 0.1 7.5e-19 68.2 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 EAQ87764.1 - 1.4e-06 28.2 0.3 2.6e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ87764.1 - 1e-05 25.5 0.3 1.8e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 EAQ87764.1 - 1.5e-05 24.8 12.2 1.5e-05 24.8 8.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 EAQ87764.1 - 0.034 13.8 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger Lumazine_bd PF12870.2 EAQ87764.1 - 0.61 10.1 10.8 0.037 14.0 3.2 2.0 2 0 0 2 2 2 0 Lumazine-binding domain DUF3268 PF11672.3 EAQ87764.1 - 1.2 9.2 4.1 0.6 10.2 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3268) Caldesmon PF02029.10 EAQ87764.1 - 1.4 7.2 25.8 0.24 9.7 14.6 1.7 2 0 0 2 2 2 0 Caldesmon Rrp15p PF07890.7 EAQ87764.1 - 2.1 8.4 16.8 0.31 11.0 6.4 2.2 2 0 0 2 2 2 0 Rrp15p DUF1764 PF08576.5 EAQ87764.1 - 4.5 8.1 11.7 5.9 7.7 4.8 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Glyco_hydro_61 PF03443.9 EAQ87765.1 - 1e-36 126.8 0.0 1.3e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ87765.1 - 8.5e-12 44.5 9.3 3e-11 42.7 6.4 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAQ87765.1 - 0.087 12.8 3.0 0.19 11.8 2.1 1.5 1 0 0 1 1 1 0 Toxin 7 UQ_con PF00179.21 EAQ87767.1 - 2.1e-37 127.7 0.0 2.5e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ87767.1 - 0.00042 20.0 0.1 0.00083 19.1 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.1 EAQ87768.1 - 2.3e-24 86.0 0.1 1.8e-23 83.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EAQ87769.1 - 3.4e-23 82.1 0.0 4.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family SOG2 PF10428.4 EAQ87769.1 - 7.5 5.0 9.6 11 4.5 6.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Mito_carr PF00153.22 EAQ87770.1 - 3.4e-17 61.9 0.3 6.1e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 EAQ87771.1 - 3.2e-22 78.0 3.6 5.7e-16 58.0 0.3 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein NTPase_P4 PF11602.3 EAQ87771.1 - 0.16 10.9 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 TFIIIC_delta PF12657.2 EAQ87772.1 - 2.1e-17 63.3 0.0 1.1e-08 35.0 0.0 2.8 3 0 0 3 3 3 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EAQ87772.1 - 2e-06 27.5 0.4 4.2e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.13 EAQ87773.1 - 2.4e-41 141.7 0.2 3.3e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_1 PF00300.17 EAQ87774.1 - 1.9e-08 34.5 0.0 1.8e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Med3 PF11593.3 EAQ87775.1 - 9.8 5.2 8.5 13 4.9 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.2 EAQ87777.1 - 2e-07 30.6 0.7 4.1e-07 29.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ87777.1 - 8.7e-06 25.2 1.0 1.7e-05 24.3 0.7 1.5 1 0 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.19 EAQ87778.1 - 7.2e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAQ87778.1 - 0.0013 18.8 0.0 0.0094 16.0 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ87778.1 - 0.019 14.6 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 EAQ87778.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dimer_Tnp_hAT PF05699.9 EAQ87779.1 - 1.2e-15 56.8 0.1 2.8e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Baculo_ME53 PF06061.6 EAQ87779.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 TauD PF02668.11 EAQ87780.1 - 2.9e-30 105.7 0.0 3.8e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EAQ87780.1 - 0.0013 17.6 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 CsiD PPP4R2 PF09184.6 EAQ87782.1 - 0.72 9.3 2.9 1 8.8 2.0 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 EAQ87782.1 - 3.6 7.3 20.7 4.1 7.2 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 EAQ87783.1 - 1.3e-07 31.0 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EAQ87783.1 - 6.6e-05 22.5 0.1 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EAQ87783.1 - 0.0033 17.1 0.1 0.0061 16.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BSP_II PF05432.6 EAQ87785.1 - 0.44 9.7 7.8 0.28 10.4 4.3 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Rhodanese PF00581.15 EAQ87786.1 - 2.4e-17 63.3 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CD34_antigen PF06365.7 EAQ87787.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM51 PF15345.1 EAQ87787.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.1 EAQ87787.1 - 0.024 14.9 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EAQ87787.1 - 0.042 12.6 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EAQ87787.1 - 0.046 11.9 0.1 0.074 11.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3609 PF12259.3 EAQ87787.1 - 0.087 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF912 PF06024.7 EAQ87787.1 - 0.097 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AMA-1 PF02430.10 EAQ87787.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 UPF0121 PF03661.8 EAQ87788.1 - 3.2e-08 33.0 3.3 8.2e-08 31.7 2.3 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Pribosyl_synth PF14572.1 EAQ87791.1 - 1.9e-35 122.2 2.6 7.9e-31 107.2 0.7 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EAQ87791.1 - 4.2e-32 110.3 0.3 5.8e-31 106.6 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EAQ87791.1 - 2e-12 46.9 0.2 5.5e-12 45.4 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EAQ87791.1 - 0.0021 17.3 0.3 0.0044 16.2 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EAQ87791.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain AF2331-like PF14556.1 EAQ87791.1 - 0.089 13.1 0.5 7.6 6.9 0.0 3.0 3 0 0 3 3 3 0 AF2331-like Chlorosome_CsmC PF11098.3 EAQ87791.1 - 0.56 9.9 3.8 2 8.1 2.4 2.1 1 1 1 2 2 2 0 Chlorosome envelope protein C AflR PF08493.5 EAQ87792.1 - 1.8 7.5 3.8 2.2 7.2 2.6 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein GRP PF07172.6 EAQ87792.1 - 3.3 8.2 19.7 55 4.3 0.0 2.1 2 0 0 2 2 2 0 Glycine rich protein family HTH_Tnp_IS1 PF12759.2 EAQ87793.1 - 0.14 11.5 0.5 1.2 8.5 0.1 2.1 2 0 0 2 2 2 0 InsA C-terminal domain Pkinase PF00069.20 EAQ87796.1 - 5.5e-71 238.7 0.0 8.7e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87796.1 - 7.8e-34 116.9 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EAQ87796.1 - 2.3e-10 40.8 1.4 8.9e-10 38.9 1.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAQ87796.1 - 0.00074 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ87796.1 - 0.057 12.4 0.1 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGI PF00342.14 EAQ87797.1 - 3.7e-209 695.1 0.2 4.3e-209 694.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CUE PF02845.11 EAQ87798.1 - 7.5e-09 34.9 0.0 1.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain Kelch_5 PF13854.1 EAQ87800.1 - 3.8e-13 49.0 14.6 6.5e-08 32.3 0.2 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EAQ87800.1 - 2.6e-10 40.1 16.4 6.9e-06 26.0 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EAQ87800.1 - 1.7e-08 34.1 8.2 0.099 12.4 0.2 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EAQ87800.1 - 9.5e-08 31.8 11.1 0.05 13.8 0.3 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EAQ87800.1 - 0.00042 19.9 3.3 0.043 13.6 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 EAQ87800.1 - 0.00082 18.8 5.7 0.066 12.7 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Gly_transf_sug PF04488.10 EAQ87801.1 - 3.6e-08 33.7 0.0 6.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EAQ87801.1 - 0.0095 15.1 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EAQ87801.1 - 0.049 12.1 0.0 0.072 11.5 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain SKG6 PF08693.5 EAQ87802.1 - 2.1e-05 23.7 0.1 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4229 PF14012.1 EAQ87802.1 - 0.066 13.1 0.2 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) PIF1 PF05970.9 EAQ87803.1 - 2.3e-32 112.3 0.0 4.3e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 EAQ87803.1 - 1.6e-26 93.1 2.8 3.5e-22 79.0 0.2 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAQ87803.1 - 8.7e-06 25.4 0.0 2.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ87803.1 - 1.6e-05 24.9 0.0 4.7e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ87803.1 - 0.00035 20.2 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ87803.1 - 0.00066 17.5 0.0 0.0011 16.8 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EAQ87803.1 - 0.023 14.2 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 EAQ87803.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin Nif11 PF07862.6 EAQ87803.1 - 0.14 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function KAP_NTPase PF07693.9 EAQ87803.1 - 0.68 8.8 0.0 1.1 8.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain NmrA PF05368.8 EAQ87804.1 - 3.4e-05 23.2 0.0 6.3e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ87804.1 - 0.001 19.1 0.1 0.0021 18.0 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding RVT_1 PF00078.22 EAQ87806.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HSP70 PF00012.15 EAQ87807.1 - 1.3e-06 26.6 0.0 0.0019 16.2 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Zn_Tnp_IS91 PF14319.1 EAQ87807.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF4379 PF14311.1 EAQ87807.1 - 0.076 12.8 0.1 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4379) SnoaL_4 PF13577.1 EAQ87808.1 - 2.7e-14 53.1 0.2 3.4e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EAQ87808.1 - 0.013 15.8 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.7 EAQ87808.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase p450 PF00067.17 EAQ87809.1 - 5.8e-36 123.9 0.0 8.8e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3HCDH_N PF02737.13 EAQ87810.1 - 3.9e-26 91.8 0.0 1.3e-25 90.0 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EAQ87810.1 - 6.9e-15 55.2 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 EAQ87810.1 - 0.00083 18.5 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EAQ87810.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EAQ87810.1 - 0.0018 18.6 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EAQ87810.1 - 0.0042 17.0 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 EAQ87810.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EAQ87810.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EAQ87810.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EAQ87810.1 - 0.19 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gp_dh_N PF00044.19 EAQ87810.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PHD PF00628.24 EAQ87812.1 - 0.0015 18.1 8.7 0.0026 17.4 6.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EAQ87812.1 - 0.04 13.2 1.9 0.064 12.5 1.3 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EAQ87812.1 - 0.25 11.1 9.2 0.4 10.4 6.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EAQ87812.1 - 1.7 8.0 7.5 0.3 10.4 2.2 1.9 2 0 0 2 2 2 0 PHD-finger CoA_transf_3 PF02515.12 EAQ87813.1 - 3.2e-58 196.1 0.0 7.1e-58 194.9 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III zf-met PF12874.2 EAQ87814.1 - 7e-06 26.0 1.3 1.5e-05 25.0 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EAQ87814.1 - 0.00019 21.0 0.1 0.00028 20.4 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EAQ87814.1 - 0.058 12.6 0.9 0.1 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 EAQ87815.1 - 5.7e-56 189.5 0.2 1.6e-39 135.6 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87815.1 - 2.4e-26 92.3 0.2 2.5e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ87815.1 - 5.2e-05 22.3 0.0 9.9e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ87815.1 - 0.00017 21.3 0.2 0.012 15.3 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EAQ87815.1 - 0.00063 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EAQ87815.1 - 0.017 15.6 0.2 0.039 14.4 0.1 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EAQ87815.1 - 0.041 12.6 0.1 0.066 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EAQ87815.1 - 0.054 12.3 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EAQ87815.1 - 0.17 11.2 2.8 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.3 EAQ87816.1 - 1.3e-136 455.2 1.2 1.5e-136 454.9 0.8 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Cyclin PF08613.6 EAQ87818.1 - 2e-13 50.9 0.0 3.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF221 PF02714.10 EAQ87818.1 - 0.0042 15.9 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF1658 PF07871.6 EAQ87819.1 - 0.41 10.3 2.5 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) HCV_NS5a_1a PF08300.8 EAQ87819.1 - 0.48 10.3 5.2 0.53 10.2 2.4 2.0 3 0 0 3 3 3 0 Hepatitis C virus non-structural 5a zinc finger domain CRC_subunit PF08624.5 EAQ87820.1 - 5.3e-59 198.0 0.1 8.4e-59 197.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF2890 PF11081.3 EAQ87820.1 - 0.5 10.3 9.6 0.97 9.4 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EAQ87820.1 - 1.8 6.5 5.1 2.4 6.0 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EAQ87820.1 - 3.1 5.5 12.0 5.9 4.6 8.3 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIB PF00382.14 EAQ87821.1 - 1.3e-35 121.0 1.8 2.3e-19 68.9 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EAQ87821.1 - 1e-12 47.1 1.7 1.6e-12 46.5 1.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EAQ87821.1 - 0.00046 20.0 0.0 1.3 9.0 0.0 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain PDZ_2 PF13180.1 EAQ87821.1 - 0.019 14.8 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 PDZ domain PhnA_Zn_Ribbon PF08274.7 EAQ87821.1 - 0.03 14.1 1.7 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Cyclin_N PF00134.18 EAQ87821.1 - 0.07 12.7 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF1191 PF06697.7 EAQ87822.1 - 0.019 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Seryl_tRNA_N PF02403.17 EAQ87822.1 - 0.02 14.9 4.2 0.032 14.2 2.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Herpes_gE PF02480.11 EAQ87822.1 - 0.034 12.4 0.0 0.044 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4263 PF14082.1 EAQ87822.1 - 0.059 13.3 0.5 0.091 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) BCLP PF12304.3 EAQ87822.1 - 0.089 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Beta-casein like protein Asn_synthase PF00733.16 EAQ87824.1 - 1.9e-54 184.8 0.0 2.5e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EAQ87824.1 - 4e-08 33.0 0.1 1.7e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EAQ87824.1 - 8.1e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EAQ87824.1 - 0.0035 16.5 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EAQ87824.1 - 0.05 12.4 0.0 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 NAD synthase VPS9 PF02204.13 EAQ87825.1 - 6.3e-16 58.2 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EAQ87825.1 - 4.3e-09 35.6 0.2 2.3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 CUE domain zf-RVT PF13966.1 EAQ87826.1 - 0.015 15.5 1.5 0.024 14.9 0.2 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF3085 PF11284.3 EAQ87826.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) MT0933_antitox PF14013.1 EAQ87827.1 - 1.4 9.0 4.6 1.9 8.6 1.6 2.5 2 1 0 2 2 2 0 MT0933-like antitoxin protein Cyt-b5 PF00173.23 EAQ87828.1 - 3.5e-14 52.3 0.0 5.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GMC_oxred_N PF00732.14 EAQ87829.1 - 3.7e-60 203.5 0.0 4.9e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ87829.1 - 1.2e-30 106.7 0.1 2.7e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAQ87829.1 - 3.3e-06 27.0 0.1 1.1e-05 25.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ87829.1 - 9.9e-06 24.6 3.8 0.00017 20.6 2.1 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ87829.1 - 2.8e-05 23.1 4.2 0.00047 19.1 2.9 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EAQ87829.1 - 5.2e-05 22.3 0.2 8.7e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EAQ87829.1 - 6.7e-05 23.0 0.2 0.073 13.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ87829.1 - 0.0015 17.6 0.0 0.0036 16.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ87829.1 - 0.0024 17.8 0.0 0.0064 16.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ87829.1 - 0.0027 16.8 0.4 0.005 15.9 0.1 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EAQ87829.1 - 0.0054 15.2 0.1 0.0083 14.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein TrkA_N PF02254.13 EAQ87829.1 - 0.015 15.3 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EAQ87829.1 - 0.02 15.2 0.1 0.057 13.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EAQ87829.1 - 0.032 12.8 0.2 0.046 12.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EAQ87829.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding PIF1 PF05970.9 EAQ87830.1 - 2.4e-32 112.2 0.0 4.4e-28 98.2 0.0 2.4 2 1 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 EAQ87830.1 - 7.1e-27 94.3 0.3 1.3e-26 93.5 0.2 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAQ87830.1 - 8.8e-06 25.4 0.0 2.6e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ87830.1 - 1.6e-05 24.9 0.0 4.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ87830.1 - 0.00035 20.2 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ87830.1 - 0.00067 17.5 0.0 0.0011 16.8 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EAQ87830.1 - 0.024 14.1 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 EAQ87830.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Torsin Nif11 PF07862.6 EAQ87830.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function KAP_NTPase PF07693.9 EAQ87830.1 - 0.68 8.8 0.0 1.1 8.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain TIM PF00121.13 EAQ87831.1 - 2.8e-47 160.8 0.0 7.2e-47 159.5 0.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EAQ87832.1 - 1.3e-40 138.2 0.9 1.5e-40 138.0 0.6 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF3773 PF12608.3 EAQ87832.1 - 0.014 15.4 0.2 0.046 13.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3773) Dak1 PF02733.12 EAQ87833.1 - 8.1e-109 363.1 0.0 1.1e-108 362.6 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EAQ87833.1 - 1.2e-37 129.2 5.7 2.4e-37 128.2 4.0 1.5 1 0 0 1 1 1 1 DAK2 domain TSA PF03249.8 EAQ87833.1 - 0.11 11.0 1.2 0.18 10.3 0.8 1.2 1 0 0 1 1 1 0 Type specific antigen DUF2497 PF10691.4 EAQ87833.1 - 0.21 11.5 0.6 22 5.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2497) F_bP_aldolase PF01116.15 EAQ87834.1 - 2.2e-85 286.2 0.3 2.5e-85 286.0 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 EAQ87834.1 - 0.051 12.5 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family NAD_binding_11 PF14833.1 EAQ87835.1 - 6.5e-38 129.5 4.8 1.4e-26 92.9 0.2 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EAQ87835.1 - 1.3e-33 116.1 0.2 2.6e-33 115.1 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pre-SET PF05033.11 EAQ87835.1 - 1.3e-19 70.3 3.5 1.3e-19 70.3 2.4 2.2 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.23 EAQ87835.1 - 5.2e-18 65.8 0.7 1.4e-16 61.2 0.0 2.9 2 1 0 2 2 2 1 SET domain F420_oxidored PF03807.12 EAQ87835.1 - 0.0002 21.7 0.2 0.00075 19.8 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EAQ87835.1 - 0.0028 17.3 0.2 0.0028 17.3 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EAQ87835.1 - 0.018 14.4 0.2 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Gly_transf_sug PF04488.10 EAQ87837.1 - 1.9e-13 50.7 0.0 3.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EAQ87837.1 - 0.0044 15.5 0.1 0.0071 14.8 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EAQ87837.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Mucin PF01456.12 EAQ87837.1 - 0.38 10.5 15.0 0.68 9.6 10.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M20 PF01546.23 EAQ87838.1 - 2.4e-15 56.5 0.0 3.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PG_binding_2 PF08823.6 EAQ87838.1 - 0.011 15.7 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain adh_short PF00106.20 EAQ87839.1 - 9.9e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAQ87839.1 - 1.7e-05 24.9 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EAQ87839.1 - 0.00031 20.6 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ87839.1 - 0.0047 16.3 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EAQ87839.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Adaptin_N PF01602.15 EAQ87840.1 - 8.8e-92 308.1 5.4 1.6e-91 307.2 3.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EAQ87840.1 - 3.9e-62 207.7 0.0 1.1e-61 206.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EAQ87840.1 - 2.6e-61 205.3 0.5 5.4e-61 204.3 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EAQ87840.1 - 2.6e-10 40.4 9.3 4.2e-05 23.7 0.0 4.9 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EAQ87840.1 - 9.3e-06 25.5 5.4 0.0012 18.7 0.0 3.8 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EAQ87840.1 - 0.00055 19.7 0.2 2.1 8.6 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EAQ87840.1 - 0.031 14.7 1.8 4.9 7.7 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat RE_Alw26IDE PF09665.5 EAQ87840.1 - 0.32 9.6 4.7 0.26 9.9 0.6 2.6 2 1 1 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 EAQ87841.1 - 1.4e-75 251.7 0.4 1.6e-75 251.5 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 EAQ87842.1 - 1.7e-62 210.0 3.3 2.1e-62 209.7 2.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.13 EAQ87843.1 - 1.4e-06 28.0 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EAQ87843.1 - 0.0075 16.2 0.0 0.027 14.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ribonuc_P_40 PF08584.6 EAQ87844.1 - 6.4e-54 182.8 0.0 7.5e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit EF_assoc_1 PF08355.7 EAQ87844.1 - 0.0076 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Ank_5 PF13857.1 EAQ87845.1 - 1.9e-10 40.6 0.0 1.9e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ87845.1 - 8.1e-07 29.3 0.1 5.6e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ87845.1 - 0.072 13.4 0.1 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) RNA_lig_T4_1 PF09511.5 EAQ87846.1 - 1.1e-80 270.2 0.0 2.2e-80 269.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EAQ87846.1 - 1.1e-75 254.2 0.0 5e-75 252.0 0.0 1.9 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EAQ87846.1 - 1.4e-56 190.9 0.1 2.7e-56 190.0 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.5 EAQ87846.1 - 0.016 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 EAQ87846.1 - 0.021 15.6 0.1 0.26 12.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain Glycos_transf_3 PF00591.16 EAQ87847.1 - 9.9e-60 202.0 0.0 3.8e-59 200.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EAQ87847.1 - 6e-09 35.3 0.0 1.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Pal1 PF08316.6 EAQ87848.1 - 0.14 12.6 0.1 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein Tic20 PF09685.5 EAQ87849.1 - 6.5e-07 29.3 1.3 8.8e-07 28.8 0.9 1.2 1 0 0 1 1 1 1 Tic20-like protein DUF2079 PF09852.4 EAQ87849.1 - 0.043 12.5 3.9 0.057 12.1 2.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) AAA PF00004.24 EAQ87850.1 - 4.7e-41 140.0 0.0 7.6e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ87850.1 - 6.5e-06 25.9 0.1 3.7e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ87850.1 - 3.7e-05 23.8 0.1 0.002 18.1 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EAQ87850.1 - 4.6e-05 22.5 0.0 0.00012 21.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAQ87850.1 - 6.4e-05 23.0 0.2 0.0064 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EAQ87850.1 - 0.00026 20.9 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EAQ87850.1 - 0.0012 18.1 0.2 0.016 14.4 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EAQ87850.1 - 0.0032 16.6 0.1 0.007 15.5 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EAQ87850.1 - 0.0044 16.9 0.0 0.0059 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ87850.1 - 0.0062 15.9 1.7 0.11 11.9 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ87850.1 - 0.0063 16.2 0.6 0.015 15.0 0.3 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 EAQ87850.1 - 0.0068 17.2 0.2 0.018 15.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAQ87850.1 - 0.0081 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EAQ87850.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EAQ87850.1 - 0.027 14.0 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAQ87850.1 - 0.048 13.5 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAQ87850.1 - 0.048 12.7 0.1 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EAQ87850.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EAQ87850.1 - 0.11 11.9 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.1 EAQ87850.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ87850.1 - 0.15 11.6 0.2 4.9 6.7 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Clr5 PF14420.1 EAQ87851.1 - 2.6e-14 52.8 2.2 4.7e-14 52.0 1.5 1.5 1 0 0 1 1 1 1 Clr5 domain Ish1 PF10281.4 EAQ87852.1 - 1.3e-56 188.1 15.8 2.4e-13 49.8 0.0 6.7 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EAQ87852.1 - 2.4e-06 26.9 0.0 0.036 13.5 0.0 3.9 5 0 0 5 5 5 2 SAP domain Slx4 PF09494.5 EAQ87852.1 - 0.0024 17.5 0.1 7.4 6.3 0.0 3.6 3 1 0 3 3 3 2 Slx4 endonuclease HeH PF12949.2 EAQ87852.1 - 0.003 17.0 0.0 4.1 7.0 0.0 4.2 4 0 0 4 4 4 1 HeH/LEM domain ApoO PF09769.4 EAQ87852.1 - 0.075 12.7 0.4 3.5 7.3 0.0 2.7 2 0 0 2 2 2 0 Apolipoprotein O APC2 PF08672.6 EAQ87852.1 - 0.12 12.6 0.2 40 4.5 0.0 3.8 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 YtxH PF12732.2 EAQ87852.1 - 1.6 9.1 8.5 4.5 7.7 0.7 3.6 3 1 0 3 3 3 0 YtxH-like protein Glyco_hydro_61 PF03443.9 EAQ87854.1 - 3.3e-42 144.7 0.1 3.9e-42 144.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AMP-binding PF00501.23 EAQ87855.1 - 7.1e-39 133.3 0.0 1.5e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ87855.1 - 4.6e-15 56.3 0.0 9.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.21 EAQ87856.1 - 8.5e-61 205.6 0.1 1.5e-60 204.8 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ87856.1 - 3.2e-56 189.8 0.3 3.2e-56 189.8 0.2 2.5 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.16 EAQ87856.1 - 8.1e-54 183.0 1.1 1.1e-53 182.6 0.1 1.7 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 EAQ87856.1 - 1.9e-41 141.7 2.8 5.4e-41 140.2 0.3 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ87856.1 - 1.2e-38 131.6 0.1 3e-38 130.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EAQ87856.1 - 1.4e-30 106.4 0.4 5.5e-30 104.5 0.2 1.9 1 1 1 2 2 2 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EAQ87856.1 - 1.6e-21 76.2 0.0 6.2e-21 74.3 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ87856.1 - 2.4e-14 54.3 0.0 2e-13 51.3 0.0 2.8 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EAQ87856.1 - 1.8e-13 50.7 0.0 5.4e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ87856.1 - 2.1e-07 31.5 0.0 9.2e-07 29.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ87856.1 - 1.7e-06 28.2 0.0 4.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EAQ87856.1 - 1.1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ87856.1 - 2.5e-05 24.6 0.0 8.2e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ87856.1 - 7e-05 22.6 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EAQ87856.1 - 0.0021 17.5 0.0 0.0074 15.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Thiolase_N PF00108.18 EAQ87856.1 - 0.0032 16.5 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain PCMT PF01135.14 EAQ87856.1 - 0.0036 16.8 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_N PF08240.7 EAQ87856.1 - 0.0044 16.7 0.1 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Transferase PF02458.10 EAQ87857.1 - 1.1e-26 93.3 0.0 1e-16 60.4 0.0 2.9 2 1 0 2 2 2 2 Transferase family AMP-binding PF00501.23 EAQ87858.1 - 1.1e-178 593.9 0.1 1.8e-90 303.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EAQ87858.1 - 6.5e-115 383.1 0.0 1.4e-39 135.7 0.0 5.5 4 1 1 5 5 5 5 Condensation domain PP-binding PF00550.20 EAQ87858.1 - 2e-44 149.6 0.1 2.7e-10 40.3 0.0 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ87858.1 - 2.1e-10 41.3 0.0 0.0008 20.3 0.0 3.4 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EAQ87858.1 - 0.02 15.1 0.1 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 HxxPF-repeated domain Ribosomal_L50 PF10501.4 EAQ87858.1 - 1.5 8.7 0.0 89 3.1 0.0 2.4 2 0 0 2 2 2 0 Ribosomal subunit 39S 2OG-FeII_Oxy PF03171.15 EAQ87859.1 - 2.8e-15 56.3 0.0 5.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAQ87859.1 - 7.1e-14 52.3 0.0 1.1e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Annexin PF00191.15 EAQ87860.1 - 1e-68 227.1 4.9 9.9e-19 67.0 0.0 4.3 4 1 0 4 4 4 4 Annexin ACT PF01842.20 EAQ87863.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain HLH PF00010.21 EAQ87863.1 - 0.033 13.8 0.8 0.066 12.9 0.5 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain EHN PF06441.7 EAQ87864.1 - 6e-33 113.1 0.0 9.5e-33 112.4 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EAQ87864.1 - 1.8e-07 31.2 2.0 3e-07 30.5 1.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ87864.1 - 0.018 14.8 0.2 0.029 14.1 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Git3 PF11710.3 EAQ87865.1 - 1.7e-15 57.1 5.0 4.3e-15 55.8 3.5 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EAQ87865.1 - 3.2e-09 36.3 1.2 3.2e-09 36.3 0.8 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EAQ87865.1 - 0.00059 18.8 8.0 0.00099 18.0 5.5 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3_C PF11970.3 EAQ87865.1 - 0.07 12.9 0.1 0.07 12.9 0.1 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_2 PF00002.19 EAQ87865.1 - 0.071 12.1 10.1 0.12 11.4 7.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Kei1 PF08552.6 EAQ87865.1 - 0.1 12.2 2.9 0.11 12.1 0.6 2.0 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Aldo_ket_red PF00248.16 EAQ87867.1 - 1.4e-44 152.0 0.0 1.5e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EAQ87867.1 - 0.073 13.2 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CDO_I PF05995.7 EAQ87868.1 - 6.2e-40 136.2 0.0 8.8e-40 135.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EAQ87868.1 - 0.00026 20.4 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Voltage_CLC PF00654.15 EAQ87869.1 - 1.1e-89 300.9 26.5 1.1e-89 300.9 18.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EAQ87869.1 - 3e-12 46.1 0.1 5e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF754 PF05449.6 EAQ87869.1 - 0.044 13.8 1.6 0.22 11.5 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF754) DUF556 PF04476.8 EAQ87869.1 - 0.057 12.6 0.2 0.097 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF556) CBFD_NFYB_HMF PF00808.18 EAQ87870.1 - 2.5e-10 40.2 0.1 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_9 PF14580.1 EAQ87871.1 - 2.5e-50 170.4 0.1 4.6e-50 169.5 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EAQ87871.1 - 1.6e-09 37.1 6.5 1.5e-05 24.4 0.1 4.5 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ87871.1 - 6.4e-08 32.2 5.3 2.2e-07 30.5 0.1 3.5 4 1 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EAQ87871.1 - 0.00056 19.6 5.1 0.16 12.2 0.2 5.2 4 1 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EAQ87871.1 - 0.0033 17.2 7.7 1.5 9.1 0.4 5.7 6 0 0 6 6 6 1 Leucine Rich Repeat DUF4349 PF14257.1 EAQ87871.1 - 0.019 14.2 2.6 0.029 13.6 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PspB PF06667.7 EAQ87871.1 - 0.12 12.3 0.8 0.36 10.8 0.5 1.8 1 0 0 1 1 1 0 Phage shock protein B LRR_6 PF13516.1 EAQ87871.1 - 0.73 10.0 4.0 4.5 7.6 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.20 EAQ87872.1 - 2.1e-28 99.1 0.0 3.1e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EAQ87872.1 - 3.5e-16 58.3 3.2 5.8e-09 35.5 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 EAQ87872.1 - 6.5e-08 31.9 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EAQ87872.1 - 2.9e-07 29.9 1.5 0.6 10.3 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EAQ87872.1 - 0.0068 16.6 0.2 1.6 9.1 0.0 3.3 1 1 3 4 4 4 2 HEAT repeats Kinase-like PF14531.1 EAQ87872.1 - 0.17 10.7 0.0 0.33 9.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RasGEF_N_2 PF14663.1 EAQ87872.1 - 0.21 11.5 0.0 0.53 10.2 0.0 1.7 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Adaptin_N PF01602.15 EAQ87872.1 - 0.75 8.0 0.0 1.9 6.7 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region SH3_9 PF14604.1 EAQ87873.1 - 1.9e-06 27.3 0.2 4.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ87873.1 - 0.0025 17.1 0.3 0.005 16.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.5 EAQ87873.1 - 0.0029 16.8 3.1 0.0068 15.6 2.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EAQ87873.1 - 0.0043 16.4 0.1 0.008 15.6 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.15 EAQ87873.1 - 0.1 12.2 0.2 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Metallophos PF00149.23 EAQ87874.1 - 2.3e-44 151.1 1.0 2.8e-44 150.9 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 EAQ87875.1 - 2.7e-17 62.3 2.5 2.7e-17 62.3 1.8 2.6 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 EAQ87875.1 - 0.00028 20.7 2.4 0.018 14.8 0.1 2.5 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_B PF00052.13 EAQ87875.1 - 0.0074 15.8 1.3 0.034 13.7 0.2 2.5 2 1 0 2 2 2 1 Laminin B (Domain IV) DASH_Dam1 PF08653.5 EAQ87875.1 - 0.13 12.0 1.9 29 4.5 0.1 3.4 2 1 0 2 2 2 0 DASH complex subunit Dam1 V_ATPase_I PF01496.14 EAQ87875.1 - 0.75 7.5 7.0 0.83 7.4 0.3 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EAQ87875.1 - 3.9 6.4 11.1 0.14 11.1 1.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 EAQ87875.1 - 5.6 5.2 6.5 4.8 5.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EAQ87875.1 - 8 5.3 13.2 0.093 11.6 1.0 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Methyltransf_2 PF00891.13 EAQ87877.1 - 9.7e-30 103.5 0.0 1.6e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MAS20 PF02064.10 EAQ87878.1 - 5.6e-14 52.0 0.6 1.6e-13 50.6 0.4 1.6 1 1 0 1 1 1 1 MAS20 protein import receptor NAM-associated PF14303.1 EAQ87878.1 - 0.032 14.5 1.7 0.043 14.1 1.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PASTA PF03793.14 EAQ87878.1 - 0.037 13.6 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 PASTA domain DUF2383 PF09537.5 EAQ87878.1 - 0.12 12.6 1.9 0.25 11.6 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Trp_oprn_chp PF09534.5 EAQ87878.1 - 0.22 11.1 4.2 0.29 10.7 2.9 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rhabdo_ncap PF00945.13 EAQ87878.1 - 0.37 9.3 1.3 0.47 8.9 0.9 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF3824 PF12868.2 EAQ87878.1 - 1.2 10.0 5.4 2.1 9.2 3.7 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Radical_SAM PF04055.16 EAQ87879.1 - 1.1e-23 84.2 0.1 2e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EAQ87879.1 - 8.3e-18 64.2 0.0 2.1e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EAQ87879.1 - 8.5e-07 29.0 0.0 4e-05 23.6 0.0 2.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.2 EAQ87879.1 - 0.14 11.6 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin domain EamA PF00892.15 EAQ87880.1 - 0.00021 21.3 12.8 0.00048 20.1 8.9 1.6 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 EAQ87880.1 - 0.0088 16.2 5.8 0.0088 16.2 4.0 1.7 1 1 0 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EAQ87880.1 - 0.11 12.2 7.3 0.019 14.7 2.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EAQ87880.1 - 0.32 10.6 11.2 0.29 10.7 5.9 1.9 1 1 1 2 2 2 0 Triose-phosphate Transporter family TFIIA_gamma_C PF02751.9 EAQ87881.1 - 9.8e-26 89.3 1.6 1.3e-25 88.8 1.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EAQ87881.1 - 1.4e-25 88.6 0.2 2e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 EAQ87882.1 - 6.3e-28 96.4 30.9 7.1e-17 61.0 5.3 3.0 3 0 0 3 3 3 2 ATP synthase subunit C DUF3671 PF12420.3 EAQ87882.1 - 0.4 10.6 1.9 1.3 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function Oxidored_q2 PF00420.19 EAQ87882.1 - 1.9 8.1 8.0 1.9 8.1 3.0 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cation_efflux PF01545.16 EAQ87882.1 - 1.9 7.4 12.8 0.051 12.6 1.9 2.4 1 1 1 2 2 2 0 Cation efflux family MoCF_biosynth PF00994.19 EAQ87883.1 - 2.2e-53 179.5 1.3 5.7e-30 103.6 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EAQ87883.1 - 6.3e-31 106.9 6.2 9.6e-31 106.3 4.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EAQ87883.1 - 6e-15 54.9 0.6 1.6e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 EAQ87883.1 - 0.31 10.3 14.2 0.46 9.8 9.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ifi-6-16 PF06140.8 EAQ87884.1 - 0.017 14.8 4.7 0.019 14.7 2.2 1.9 2 0 0 2 2 2 0 Interferon-induced 6-16 family Colicin_V PF02674.11 EAQ87884.1 - 0.03 14.1 1.9 0.045 13.6 1.3 1.3 1 0 0 1 1 1 0 Colicin V production protein ATP_bind_1 PF03029.12 EAQ87885.1 - 2.7e-70 236.5 0.0 4.5e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAQ87885.1 - 0.017 15.9 4.0 0.058 14.2 0.8 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ87885.1 - 0.041 13.4 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAQ87885.1 - 0.092 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EAQ87886.1 - 6.8e-21 73.3 0.5 5.1e-06 26.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat TT_ORF2 PF02957.10 EAQ87887.1 - 5 7.8 6.6 0.84 10.3 1.2 2.2 2 1 0 2 2 2 0 TT viral ORF2 WD40 PF00400.27 EAQ87888.1 - 2.6e-39 131.6 5.2 5e-10 38.8 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EAQ87888.1 - 3.6e-07 28.7 12.7 0.0099 14.0 0.6 4.5 2 2 3 5 5 5 3 Nucleoporin Nup120/160 APG6 PF04111.7 EAQ87888.1 - 0.21 10.5 2.2 0.32 9.9 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EAQ87888.1 - 1.1 8.4 3.3 1.8 7.6 2.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CM_2 PF01817.16 EAQ87889.1 - 0.036 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Chorismate mutase type II BCIP PF13862.1 EAQ87890.1 - 8.1e-66 221.2 0.6 1.1e-65 220.7 0.4 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Med20 PF08612.6 EAQ87890.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex UPF0184 PF03670.8 EAQ87890.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) COPI_assoc PF08507.5 EAQ87891.1 - 1.4e-44 151.1 3.1 1.5e-44 151.0 2.2 1.0 1 0 0 1 1 1 1 COPI associated protein ExoD PF06055.7 EAQ87891.1 - 0.0055 15.8 3.5 0.048 12.7 0.8 2.0 2 0 0 2 2 2 1 Exopolysaccharide synthesis, ExoD 5TM-5TMR_LYT PF07694.7 EAQ87891.1 - 0.13 11.6 6.6 0.19 11.0 4.6 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF3096 PF11295.3 EAQ87891.1 - 0.45 10.0 11.7 0.72 9.4 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) DUF308 PF03729.8 EAQ87891.1 - 8.5 6.4 18.8 5.5 7.0 1.4 2.9 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) SAP PF02037.22 EAQ87894.1 - 3e-14 52.1 0.0 4.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EAQ87894.1 - 0.095 12.2 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain CPSase_sm_chain PF00988.17 EAQ87895.1 - 1.2e-47 160.6 0.0 1.9e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EAQ87895.1 - 9.8e-47 158.8 0.0 1.4e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAQ87895.1 - 9.7e-07 28.4 0.2 0.00016 21.1 0.2 2.8 1 1 0 1 1 1 1 Peptidase C26 ETF PF01012.16 EAQ87896.1 - 4.3e-37 127.3 0.4 5.4e-37 127.0 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 EAQ87897.1 - 3.6e-32 110.5 0.1 5.4e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 EAQ87898.1 - 2.3e-07 30.3 0.1 2.2e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ87898.1 - 1.3e-05 25.0 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IMPDH PF00478.20 EAQ87898.1 - 0.0083 15.0 0.1 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain RRM_5 PF13893.1 EAQ87898.1 - 0.013 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavodoxin_1 PF00258.20 EAQ87899.1 - 5.5e-28 97.7 0.0 1.7e-27 96.1 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 EAQ87899.1 - 1.8e-25 89.6 0.0 2.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EAQ87899.1 - 6.8e-08 33.0 0.0 4.7e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EAQ87899.1 - 0.065 13.2 0.0 0.21 11.5 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_3 PF12641.2 EAQ87899.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Asp PF00026.18 EAQ87900.1 - 3.9e-08 32.8 0.0 1.4e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF4366 PF14283.1 EAQ87900.1 - 0.007 15.8 0.2 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) CCSMST1 PF15013.1 EAQ87900.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 CCSMST1 family UIM PF02809.15 EAQ87903.1 - 9.1e-05 21.7 17.3 0.0079 15.6 1.7 4.2 4 0 0 4 4 4 3 Ubiquitin interaction motif F-box-like PF12937.2 EAQ87903.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EAQ87903.1 - 0.15 11.7 0.1 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 EAQ87903.1 - 0.22 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain FYVE_2 PF02318.11 EAQ87904.1 - 0.45 10.4 24.6 0.47 10.3 0.2 3.5 4 0 0 4 4 4 0 FYVE-type zinc finger Clr2 PF10383.4 EAQ87905.1 - 5.7e-33 113.8 0.0 1.5e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Pex14_N PF04695.8 EAQ87905.1 - 5.5 7.0 8.2 12 5.9 5.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 EAQ87905.1 - 5.8 6.1 15.4 9.7 5.4 10.7 1.3 1 0 0 1 1 1 0 Vta1 like SUN PF03856.8 EAQ87906.1 - 1.9e-75 253.4 7.3 2.4e-75 253.0 5.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF605 PF04652.11 EAQ87906.1 - 8 5.7 15.1 12 5.1 10.5 1.1 1 0 0 1 1 1 0 Vta1 like Thiolase_N PF00108.18 EAQ87908.1 - 2.9e-92 308.3 0.2 4.5e-92 307.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAQ87908.1 - 5.4e-38 129.1 0.8 1.4e-37 127.8 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EAQ87908.1 - 0.00036 20.1 0.2 0.0011 18.5 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 EAQ87909.1 - 7.6e-52 174.4 0.0 8.6e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ87909.1 - 8.5e-07 28.7 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAQ87909.1 - 0.033 14.0 0.2 0.054 13.3 0.1 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 EAQ87910.1 - 2.2e-113 378.3 0.2 5.1e-113 377.1 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain LCM PF04072.9 EAQ87912.1 - 1.7e-21 76.6 0.0 3.8e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.11 EAQ87913.1 - 6.1e-26 90.0 0.4 1.7e-24 85.4 0.0 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit LigT_PEase PF02834.11 EAQ87913.1 - 0.045 13.7 0.2 0.94 9.4 0.0 2.9 3 0 0 3 3 3 0 LigT like Phosphoesterase Myc_N PF01056.13 EAQ87913.1 - 0.047 12.8 0.5 0.067 12.3 0.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TPR_10 PF13374.1 EAQ87914.1 - 1.2e-46 155.3 0.9 4.7e-14 51.7 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ87914.1 - 1.6e-42 143.2 1.5 1.2e-13 50.8 0.0 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87914.1 - 2.1e-08 33.3 0.3 0.03 14.0 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ87914.1 - 1.1e-06 28.2 1.4 0.84 9.9 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87914.1 - 4.1e-05 23.1 0.1 0.092 12.4 0.0 3.0 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAQ87914.1 - 0.00031 20.4 2.8 4.2 7.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ87914.1 - 0.00068 19.8 0.6 3.9 8.1 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ87914.1 - 0.00073 19.0 0.3 2 8.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ87914.1 - 0.00074 20.1 0.2 1.7 9.4 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ87914.1 - 0.062 13.9 1.5 40 5.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ87914.1 - 0.074 12.8 0.3 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EAQ87914.1 - 2.8 7.7 5.9 6.9 6.5 0.1 3.1 3 1 1 4 4 4 0 Rabaptin-like protein TPR_12 PF13424.1 EAQ87915.1 - 6.7e-208 673.2 79.3 1.7e-20 72.7 0.5 8.5 2 1 10 12 12 12 12 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ87915.1 - 1.3e-156 504.8 56.0 6.5e-11 41.7 0.1 14.9 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ87915.1 - 4.8e-90 291.8 18.2 5e-05 22.7 0.0 15.1 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ87915.1 - 1.6e-66 214.9 23.3 0.0047 16.7 0.2 14.9 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87915.1 - 2.7e-66 214.1 50.3 0.0002 20.9 0.1 14.7 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87915.1 - 1e-55 185.2 59.3 9.3e-08 31.6 0.2 8.9 2 2 8 11 11 11 11 TPR repeat TPR_14 PF13428.1 EAQ87915.1 - 7.8e-46 150.3 37.3 0.18 12.5 0.0 15.1 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ87915.1 - 8.8e-45 147.1 41.7 0.023 14.4 0.1 14.8 14 0 0 14 14 14 14 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ87915.1 - 1.9e-34 114.4 0.0 9.2 7.0 0.0 15.3 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ87915.1 - 5e-32 109.8 34.7 0.0012 19.4 0.3 10.0 2 1 10 12 12 12 12 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ87915.1 - 6.8e-30 100.7 24.3 0.82 10.0 0.0 17.3 14 11 0 14 14 14 4 Tetratricopeptide repeat Patatin PF01734.17 EAQ87915.1 - 2.8e-24 86.1 0.2 6.7e-24 84.9 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_19 PF14559.1 EAQ87915.1 - 9e-24 83.6 32.8 0.029 14.7 0.2 10.6 1 1 13 14 14 14 13 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ87915.1 - 2.6e-19 68.2 60.2 1.7 9.2 0.2 15.4 14 1 0 14 14 14 6 Tetratricopeptide repeat DUF2225 PF09986.4 EAQ87915.1 - 3.3e-13 49.6 14.5 0.037 13.4 0.2 7.3 1 1 5 6 6 6 4 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.15 EAQ87915.1 - 5.4e-11 41.7 1.1 1.3e+02 2.9 0.0 13.1 15 0 0 15 15 15 0 PPR repeat Phage_integ_N PF09003.5 EAQ87915.1 - 7.7e-07 28.7 28.4 5.8 6.6 0.0 11.3 1 1 11 13 13 13 1 Bacteriophage lambda integrase, N-terminal domain TPR_21 PF09976.4 EAQ87915.1 - 4.2e-06 26.7 20.2 16 5.4 0.0 12.1 11 3 3 14 14 14 0 Tetratricopeptide repeat Pedibin PF08182.6 EAQ87915.1 - 1.6e-05 24.2 12.5 1.1e+02 2.4 0.0 9.2 9 0 0 9 9 9 0 Pedibin/Hym-346 family NB-ARC PF00931.17 EAQ87915.1 - 3.8e-05 22.6 0.0 7.7e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Rab5-bind PF09311.6 EAQ87915.1 - 0.0002 21.3 19.0 10 5.9 0.2 7.2 2 1 8 11 11 10 0 Rabaptin-like protein AAA_22 PF13401.1 EAQ87915.1 - 0.0028 17.8 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAQ87915.1 - 0.0036 17.0 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EAQ87915.1 - 0.0089 16.0 2.1 0.073 13.0 1.5 2.7 1 1 0 1 1 1 1 AAA ATPase domain CCP_MauG PF03150.9 EAQ87915.1 - 0.16 12.2 1.7 21 5.3 0.0 5.2 6 2 1 7 7 5 0 Di-haem cytochrome c peroxidase TPR_10 PF13374.1 EAQ87916.1 - 8.1e-25 85.9 0.0 8.2e-13 47.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ87916.1 - 1.7e-15 56.6 0.0 1.5e-12 47.2 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87916.1 - 5.9e-05 22.5 0.0 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ87916.1 - 0.00023 21.0 0.1 0.26 11.5 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87916.1 - 0.023 14.3 0.0 0.074 12.7 0.0 1.7 1 1 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 EAQ87916.1 - 0.028 14.3 0.1 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 EAQ87916.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.4 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.23 EAQ87916.1 - 0.072 12.7 0.1 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ist1 PF03398.9 EAQ87917.1 - 5.1e-66 221.1 0.4 5.9e-66 220.9 0.2 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RepB PF07506.6 EAQ87918.1 - 3.7 7.3 11.7 0.17 11.7 0.1 3.4 3 1 1 4 4 4 0 RepB plasmid partitioning protein Clat_adaptor_s PF01217.15 EAQ87919.1 - 1e-56 190.6 1.9 1.1e-56 190.4 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 EAQ87920.1 - 6.8e-18 64.4 40.5 4.4e-14 51.9 16.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EAQ87920.1 - 5.7e-12 45.4 3.7 5.7e-12 45.4 2.6 2.1 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.10 EAQ87921.1 - 2.3e-165 550.5 4.6 2.9e-165 550.1 3.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cys_Met_Meta_PP PF01053.15 EAQ87922.1 - 5.2e-137 456.2 0.0 6.1e-137 456.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EAQ87922.1 - 1.7e-06 27.0 0.0 3.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EAQ87922.1 - 2.4e-05 23.4 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EAQ87922.1 - 9.1e-05 21.6 0.1 0.00036 19.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EAQ87922.1 - 0.00013 20.3 0.1 0.00035 19.0 0.1 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EAQ87922.1 - 0.001 17.8 0.1 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein AAA PF00004.24 EAQ87923.1 - 3.1e-39 134.2 0.0 5e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAQ87923.1 - 4.6e-06 26.5 0.0 8.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ87923.1 - 4.8e-06 26.6 0.1 0.00014 21.8 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EAQ87923.1 - 9.1e-06 26.4 0.1 3.1e-05 24.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EAQ87923.1 - 1.1e-05 25.5 0.1 0.00019 21.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAQ87923.1 - 1.4e-05 24.2 0.0 2.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EAQ87923.1 - 3.1e-05 23.9 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAQ87923.1 - 5.2e-05 22.9 0.1 0.00056 19.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EAQ87923.1 - 0.0003 20.6 0.0 0.00074 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAQ87923.1 - 0.00091 18.3 0.1 0.0026 16.8 0.0 1.8 2 0 0 2 2 1 1 Zeta toxin Mg_chelatase PF01078.16 EAQ87923.1 - 0.0014 17.8 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EAQ87923.1 - 0.0021 17.7 0.5 0.0093 15.6 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EAQ87923.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EAQ87923.1 - 0.0033 17.5 0.0 0.0082 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EAQ87923.1 - 0.0048 16.3 1.7 0.14 11.5 0.1 2.8 2 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EAQ87923.1 - 0.0051 17.1 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ87923.1 - 0.0067 16.0 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.1 EAQ87923.1 - 0.0073 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 EAQ87923.1 - 0.0074 16.2 0.1 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Oxidored_nitro PF00148.14 EAQ87923.1 - 0.0098 14.5 0.0 0.12 10.9 0.0 2.1 2 0 0 2 2 2 1 Nitrogenase component 1 type Oxidoreductase AAA_24 PF13479.1 EAQ87923.1 - 0.016 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EAQ87923.1 - 0.018 14.4 0.0 0.049 13.1 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EAQ87923.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EAQ87923.1 - 0.025 14.2 0.0 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase TIP49 PF06068.8 EAQ87923.1 - 0.033 12.9 0.0 0.058 12.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus DUF815 PF05673.8 EAQ87923.1 - 0.038 12.8 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EAQ87923.1 - 0.042 12.7 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EAQ87923.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 EAQ87923.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Csm1 PF12539.3 EAQ87924.1 - 1.7e-24 86.0 0.0 3.2e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 IncA PF04156.9 EAQ87924.1 - 0.00048 19.7 2.4 0.001 18.7 1.6 1.5 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 EAQ87924.1 - 0.0018 17.2 2.9 0.0035 16.3 2.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FTA4 PF13093.1 EAQ87924.1 - 0.0064 15.9 2.3 0.011 15.1 1.6 1.4 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TBPIP PF07106.8 EAQ87924.1 - 0.014 14.9 1.0 0.026 14.0 0.7 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 EAQ87924.1 - 0.017 13.6 4.4 0.026 12.9 3.0 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EAQ87924.1 - 0.024 13.8 2.9 0.036 13.2 2.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EAQ87924.1 - 0.042 12.5 2.9 0.061 11.9 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Phlebovirus_NSM PF07246.6 EAQ87924.1 - 0.066 12.3 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1759 PF03564.10 EAQ87924.1 - 0.067 13.0 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) ADIP PF11559.3 EAQ87924.1 - 0.092 12.6 5.3 0.19 11.6 3.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 EAQ87924.1 - 0.1 11.0 1.6 0.17 10.2 1.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Fib_alpha PF08702.5 EAQ87924.1 - 0.18 11.9 2.0 0.45 10.6 1.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Bap31 PF05529.7 EAQ87924.1 - 0.5 9.8 2.0 1.3 8.4 1.4 1.8 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF2203 PF09969.4 EAQ87924.1 - 0.6 10.3 2.3 2.2 8.4 1.6 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.17 EAQ87924.1 - 2.7 8.0 8.1 0.7 9.9 2.5 2.2 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EAQ87924.1 - 6.5 6.5 12.9 0.5 10.1 5.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HR1 PF02185.11 EAQ87924.1 - 7.6 6.3 9.4 53 3.6 5.3 2.6 1 1 1 2 2 2 0 Hr1 repeat PGAP1 PF07819.8 EAQ87925.1 - 1.7e-88 295.9 0.0 2.5e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EAQ87925.1 - 4.5e-07 29.7 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ87925.1 - 8.5e-05 22.5 0.1 0.00018 21.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ87925.1 - 0.0038 16.8 0.2 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EAQ87925.1 - 0.045 13.0 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DNA_mis_repair PF01119.14 EAQ87926.1 - 1.5e-17 63.1 0.0 5.4e-17 61.3 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EAQ87926.1 - 2.2e-15 56.5 0.1 6.6e-15 54.9 0.1 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EAQ87926.1 - 4.2e-07 29.6 0.5 2.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAQ87926.1 - 1.4e-06 28.0 0.0 3.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_3 PF13738.1 EAQ87928.1 - 1e-05 25.7 0.0 0.00047 20.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ87928.1 - 1.9e-05 24.6 0.0 0.00016 21.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ87928.1 - 0.0069 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAQ87928.1 - 0.038 12.4 0.0 0.06 11.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EAQ87928.1 - 0.17 12.3 0.1 3.1 8.2 0.1 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ87928.1 - 0.18 11.5 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding ETF_alpha PF00766.14 EAQ87929.1 - 0.00021 20.8 0.1 0.00021 20.8 0.1 1.0 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 EAQ87930.1 - 1.1e-35 121.6 0.1 2e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EAQ87930.1 - 1.6e-07 31.2 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ87930.1 - 2.8e-05 24.1 0.4 5.6e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EAQ87930.1 - 0.018 14.5 3.1 0.034 13.6 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Carn_acyltransf PF00755.15 EAQ87931.1 - 3.2e-178 593.5 0.0 3.7e-178 593.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.14 EAQ87932.1 - 6.6e-84 281.8 18.7 7e-84 281.7 11.5 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EAQ87932.1 - 5.2e-55 185.1 2.3 7.7e-55 184.5 1.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EAQ87932.1 - 0.14 11.6 1.4 0.33 10.3 0.8 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C PfkB PF00294.19 EAQ87933.1 - 2.8e-14 52.9 0.0 6.4e-09 35.3 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.18 EAQ87934.1 - 3.5e-72 243.0 4.3 7.2e-37 126.9 0.5 2.1 1 1 1 2 2 2 2 MCM2/3/5 family Pentapeptide_2 PF01469.13 EAQ87935.1 - 0.41 10.3 4.9 8.1 6.1 0.3 2.9 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) Aminotran_3 PF00202.16 EAQ87937.1 - 1e-82 277.7 0.0 1.3e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EAQ87937.1 - 0.0072 15.3 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Exo70 PF03081.10 EAQ87938.1 - 1.2e-67 228.3 0.0 2.6e-67 227.2 0.0 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.7 EAQ87938.1 - 0.11 12.3 3.0 39 4.0 0.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 EAQ87938.1 - 0.6 10.3 5.9 7.5 6.7 0.3 3.4 3 0 0 3 3 3 0 Syntaxin Pkinase PF00069.20 EAQ87942.1 - 1.6e-06 27.4 0.0 9.9e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ87942.1 - 0.0032 16.5 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AXE1 PF05448.7 EAQ87942.1 - 0.016 13.7 0.0 0.024 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Kdo PF06293.9 EAQ87942.1 - 0.023 13.7 0.0 0.088 11.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ87942.1 - 0.03 14.0 2.2 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAQ87942.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CDC45 PF02724.9 EAQ87942.1 - 0.082 10.9 0.5 0.093 10.7 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EAQ87942.1 - 0.55 9.4 3.8 0.83 8.8 2.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EAQ87942.1 - 5.3 7.3 9.8 11 6.3 6.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fungal_trans_2 PF11951.3 EAQ87943.1 - 3.1e-14 52.3 3.8 4.7e-14 51.7 2.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ87943.1 - 8.3e-06 25.6 10.4 1.5e-05 24.7 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FtsK_SpoIIIE PF01580.13 EAQ87944.1 - 0.0022 17.5 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family B12-binding PF02310.14 EAQ87944.1 - 0.021 14.6 0.2 0.045 13.6 0.2 1.5 2 0 0 2 2 2 0 B12 binding domain TroA PF01297.12 EAQ87944.1 - 0.034 13.4 0.0 0.036 13.3 0.0 1.0 1 0 0 1 1 1 0 Periplasmic solute binding protein family DUF3322 PF11795.3 EAQ87944.1 - 0.073 12.7 0.1 0.092 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) FAA_hydrolase PF01557.13 EAQ87945.1 - 1.5e-45 155.2 0.0 1.7e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family BRO1 PF03097.13 EAQ87946.1 - 7.7e-136 452.7 3.2 7.7e-136 452.7 2.2 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EAQ87946.1 - 4.6e-83 278.5 14.5 8.1e-83 277.7 10.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1539 PF07560.6 EAQ87946.1 - 0.23 11.3 5.6 0.3 10.9 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) DUF3012 PF11216.3 EAQ87946.1 - 6 6.6 5.5 0.82 9.4 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3012) Fungal_trans PF04082.13 EAQ87947.1 - 6.9e-37 126.7 0.0 1.1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PigN PF04987.9 EAQ87948.1 - 2.2e-168 560.5 25.8 2.7e-168 560.2 17.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EAQ87948.1 - 5.9e-10 38.9 0.1 1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAQ87948.1 - 1.6e-08 34.1 0.1 2.4e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EAQ87948.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily CDC27 PF09507.5 EAQ87949.1 - 2e-97 327.1 23.6 2.3e-97 326.9 16.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EAQ87950.1 - 3.2e-180 599.2 0.0 4e-180 598.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF1131 PF06572.7 EAQ87950.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) HNH_2 PF13391.1 EAQ87951.1 - 0.00023 20.8 0.0 0.00027 20.6 0.0 1.1 1 0 0 1 1 1 1 HNH endonuclease FSH1 PF03959.8 EAQ87952.1 - 5.1e-31 107.7 0.0 1.3e-30 106.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EAQ87952.1 - 1.6e-10 41.2 1.1 2.1e-10 40.9 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAQ87952.1 - 0.098 12.0 1.2 1.1 8.6 0.9 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase p450 PF00067.17 EAQ87953.1 - 1e-28 100.1 0.1 1.1e-27 96.6 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Syja_N PF02383.13 EAQ87955.1 - 2.8e-90 302.3 0.4 7.2e-90 300.9 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain TarH PF02203.10 EAQ87955.1 - 0.13 12.0 1.9 0.16 11.7 0.3 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF2454 PF10521.4 EAQ87956.1 - 1.9e-72 243.6 0.0 2.6e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EAQ87957.1 - 1.2e-23 83.6 0.0 1.2e-21 77.2 0.0 2.9 2 1 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EAQ87957.1 - 3.5e-08 32.8 0.0 9.2e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EAQ87957.1 - 0.038 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Sec7 PF01369.15 EAQ87958.1 - 2.5e-58 196.8 0.0 4.1e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EAQ87958.1 - 2.1e-17 63.0 0.1 7.9e-10 38.4 0.0 4.2 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 EAQ87959.1 - 5.2e-122 406.1 0.1 8.4e-121 402.2 0.0 2.0 2 0 0 2 2 2 2 Anp1 RNase_PH PF01138.16 EAQ87960.1 - 7.9e-24 84.4 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GDA1_CD39 PF01150.12 EAQ87961.1 - 5.6e-104 348.0 0.0 8.4e-104 347.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.7 EAQ87962.1 - 2.5e-24 85.9 0.0 3.1e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EAQ87963.1 - 2.6e-08 33.5 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 EAQ87964.1 - 1.9e-22 79.9 0.1 2.2e-22 79.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EAQ87965.1 - 1.2e-20 73.7 0.0 1.3e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EAQ87966.1 - 2.2e-15 56.2 0.0 4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Phe_tRNA-synt_N PF02912.13 EAQ87966.1 - 0.0069 16.0 0.3 0.012 15.3 0.2 1.2 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain RapA_C PF12137.3 EAQ87966.1 - 0.058 12.2 0.3 0.08 11.7 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Coat_F PF07875.7 EAQ87966.1 - 0.061 13.4 3.5 4 7.6 0.3 2.3 2 0 0 2 2 2 0 Coat F domain zf-C3HC4_3 PF13920.1 EAQ87967.1 - 5.2e-08 32.4 12.7 8.7e-08 31.7 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PhrC_PhrF PF11131.3 EAQ87967.1 - 0.031 13.8 0.2 0.031 13.8 0.1 2.6 3 0 0 3 3 3 0 Rap-phr extracellular signalling FAM24 PF15193.1 EAQ87967.1 - 3.8 7.7 9.8 7.6 6.8 6.8 1.5 1 0 0 1 1 1 0 FAM24 family RRM_1 PF00076.17 EAQ87968.1 - 5.5e-26 89.9 0.3 2.2e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ87968.1 - 2e-16 59.6 0.1 1e-07 31.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ87968.1 - 5.4e-16 58.1 0.0 2.3e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAQ87968.1 - 0.033 13.9 0.0 4.3 7.1 0.0 2.6 2 1 0 2 2 2 0 Limkain b1 Calcipressin PF04847.7 EAQ87968.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Calcipressin ATP-synt_D PF01813.12 EAQ87969.1 - 4.6e-44 150.3 4.2 1.2e-43 148.9 2.9 1.6 1 1 0 1 1 1 1 ATP synthase subunit D DUF2526 PF10735.4 EAQ87969.1 - 0.011 15.7 0.9 0.018 14.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) Suf PF05843.9 EAQ87970.1 - 4.5e-12 46.2 6.4 0.033 13.9 0.0 5.7 3 1 1 4 4 4 4 Suppressor of forked protein (Suf) TPR_12 PF13424.1 EAQ87970.1 - 7.2e-11 41.8 0.1 1.3 8.9 0.0 6.8 7 1 0 7 7 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ87970.1 - 4.7e-10 39.1 9.6 0.9 10.3 0.0 9.4 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ87970.1 - 1.3e-07 31.1 3.5 0.93 9.1 0.0 6.6 7 1 1 8 8 8 3 TPR repeat TPR_15 PF13429.1 EAQ87970.1 - 5.9e-07 28.8 1.1 0.00022 20.3 0.6 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EAQ87970.1 - 1.3e-06 28.2 4.9 1.1 9.0 0.1 5.9 6 0 0 6 6 6 2 Mad3/BUB1 homology region 1 RPN7 PF10602.4 EAQ87970.1 - 2.2e-05 23.9 0.1 0.00023 20.5 0.2 2.7 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EAQ87970.1 - 2.9e-05 24.3 0.9 8.8 6.7 0.0 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ87970.1 - 0.00011 22.7 10.5 0.027 15.1 0.0 6.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ87970.1 - 0.00028 20.5 15.5 0.12 12.3 0.0 6.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ87970.1 - 0.00044 19.8 2.4 1.7 8.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ87970.1 - 0.00098 19.3 0.4 0.044 14.2 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ87970.1 - 0.0017 17.9 5.7 0.36 10.7 0.0 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ87970.1 - 0.0059 16.7 0.8 13 6.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 EAQ87970.1 - 0.073 13.3 0.0 1.1 9.7 0.0 3.1 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 EAQ87970.1 - 0.64 10.5 7.9 43 4.8 0.0 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat adh_short PF00106.20 EAQ87972.1 - 5.4e-12 45.9 0.0 1.8e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ87972.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PrgI PF12666.2 EAQ87973.1 - 0.053 13.6 0.2 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 PrgI family protein Trp_oprn_chp PF09534.5 EAQ87973.1 - 0.25 10.9 4.2 0.52 9.8 2.9 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.11 EAQ87974.1 - 3.7e-13 48.9 14.5 4.9e-13 48.5 10.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ87974.1 - 0.00036 19.2 3.6 0.0004 19.0 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cyd_oper_YbgE PF09600.5 EAQ87974.1 - 0.21 11.7 4.7 0.16 12.1 2.1 1.6 1 1 1 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Fungal_trans PF04082.13 EAQ87976.1 - 9e-28 96.8 0.1 1.7e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThiF PF00899.16 EAQ87977.1 - 5.8e-10 39.1 0.0 3.3e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 ThiF family DUF3129 PF11327.3 EAQ87978.1 - 1.6e-61 207.3 11.3 2.8e-61 206.5 7.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Spore_YtfJ PF09579.5 EAQ87978.1 - 9.3 6.1 10.2 0.33 10.8 1.6 2.5 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) PEMT PF04191.8 EAQ87979.1 - 7.7e-56 186.7 18.0 5.9e-36 122.7 1.5 3.5 3 0 0 3 3 3 2 Phospholipid methyltransferase DUF1049 PF06305.6 EAQ87980.1 - 9.3 5.8 5.7 0.73 9.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) eIF3g PF12353.3 EAQ87981.1 - 2.3e-45 153.6 1.6 3.9e-45 152.8 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EAQ87981.1 - 1.6e-16 59.6 0.1 3.3e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ87981.1 - 4.4e-13 48.9 0.1 8e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ87981.1 - 2.3e-07 30.5 0.4 4.3e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2046 PF09755.4 EAQ87983.1 - 0.00039 19.4 2.7 0.00039 19.4 1.9 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) IncA PF04156.9 EAQ87983.1 - 0.014 14.9 10.0 0.17 11.4 0.8 2.1 2 0 0 2 2 2 0 IncA protein Pox_A_type_inc PF04508.7 EAQ87983.1 - 0.17 11.7 3.9 1.1 9.2 0.4 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Med9 PF07544.8 EAQ87983.1 - 0.2 11.4 4.3 5.2 6.8 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FlxA PF14282.1 EAQ87983.1 - 0.35 10.8 17.3 0.15 11.9 3.8 2.6 2 1 0 2 2 2 0 FlxA-like protein Dor1 PF04124.7 EAQ87983.1 - 4.2 5.7 7.5 2.6 6.4 1.5 2.0 2 0 0 2 2 2 0 Dor1-like family DUF972 PF06156.8 EAQ87983.1 - 5.3 7.4 6.1 6.7 7.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EAQ87983.1 - 5.4 7.1 8.4 13 5.9 0.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EAQ87983.1 - 5.7 7.3 13.0 1.9 8.9 3.0 2.7 2 1 0 2 2 2 0 SlyX DAO PF01266.19 EAQ87984.1 - 7.4e-52 176.4 4.0 8.5e-52 176.2 2.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ87984.1 - 3e-05 24.1 0.2 0.0026 17.8 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ87984.1 - 0.00018 21.4 0.7 0.00047 20.1 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAQ87984.1 - 0.056 13.8 0.0 0.66 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2415 PF10313.4 EAQ87985.1 - 2.1e-15 56.0 0.0 5.1e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Pex14_N PF04695.8 EAQ87985.1 - 0.092 12.7 2.6 0.29 11.1 1.8 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tmemb_cc2 PF10267.4 EAQ87985.1 - 0.11 11.0 2.2 0.18 10.3 1.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein HSP70 PF00012.15 EAQ87986.1 - 4e-260 863.9 17.0 4.7e-260 863.6 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ87986.1 - 2.3e-12 46.1 1.0 2.3e-12 46.1 0.7 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EAQ87986.1 - 0.00037 20.1 0.0 0.0009 18.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.1 EAQ87986.1 - 0.48 10.1 4.9 1.1 9.0 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) PPR_2 PF13041.1 EAQ87988.1 - 2e-16 59.6 2.9 1.5e-06 28.0 0.1 5.6 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 EAQ87988.1 - 1.5e-13 49.7 0.6 0.00084 19.1 0.0 7.8 8 0 0 8 8 8 2 PPR repeat PPR_3 PF13812.1 EAQ87988.1 - 7e-12 44.6 6.1 0.13 12.6 0.0 8.0 8 0 0 8 8 8 3 Pentatricopeptide repeat domain TPR_14 PF13428.1 EAQ87988.1 - 2.7e-06 27.5 2.3 1.3 9.8 0.0 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat PPR_1 PF12854.2 EAQ87988.1 - 6.2e-06 25.5 0.0 0.35 10.3 0.0 3.5 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.1 EAQ87988.1 - 0.0014 18.8 0.1 3.6 8.0 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat DUF3366 PF11846.3 EAQ87988.1 - 0.0021 17.9 0.2 0.029 14.2 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3366) ATP13 PF12921.2 EAQ87988.1 - 0.0056 16.0 0.0 0.019 14.3 0.0 2.0 1 0 0 1 1 1 1 Mitochondrial ATPase expression TPR_11 PF13414.1 EAQ87988.1 - 0.0088 15.6 0.3 0.18 11.4 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EAQ87988.1 - 0.2 11.6 4.2 12 6.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_6 PF14259.1 EAQ87989.1 - 4.6e-13 48.9 0.3 2.6e-12 46.5 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ87989.1 - 6.1e-11 42.0 0.8 4.4e-10 39.2 0.3 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ87989.1 - 3.1e-08 33.1 2.2 5.7e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EAQ87989.1 - 6.8e-07 28.8 3.1 1.2e-06 28.0 2.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 EAQ87989.1 - 7.4e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 EAQ87989.1 - 0.0028 17.3 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF1330 PF07045.6 EAQ87989.1 - 0.0085 15.9 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1330) AAA_23 PF13476.1 EAQ87989.1 - 0.012 15.9 5.2 0.019 15.3 1.9 2.1 2 0 0 2 2 2 0 AAA domain RRM_3 PF08777.6 EAQ87989.1 - 0.028 14.2 7.2 0.37 10.6 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif MTHFR PF02219.12 EAQ87990.1 - 1.8e-112 375.0 0.0 3.5e-112 374.1 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase DUF676 PF05057.9 EAQ87991.1 - 6.2e-44 149.8 0.0 1.1e-28 100.0 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) zf-C2H2_6 PF13912.1 EAQ87992.1 - 0.012 15.4 0.5 0.012 15.4 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EAQ87992.1 - 0.069 12.9 0.3 0.069 12.9 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.13 EAQ87992.1 - 0.1 12.5 7.9 0.25 11.2 5.5 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec5 PF15469.1 EAQ87993.1 - 5e-33 114.3 0.0 1.9e-32 112.4 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EAQ87993.1 - 0.00095 18.9 0.3 0.0054 16.5 0.1 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Iso_dh PF00180.15 EAQ87994.1 - 2.2e-97 326.1 0.0 2.8e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BSP PF04450.7 EAQ87997.1 - 4.3e-73 245.1 0.0 5.1e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EAQ87997.1 - 5.8e-06 26.3 0.3 0.0017 18.3 0.0 2.2 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 EAQ87997.1 - 0.053 13.1 0.1 0.091 12.4 0.0 1.5 2 0 0 2 2 2 0 SprT-like family CLASP_N PF12348.3 EAQ87998.1 - 3.5e-136 451.8 1.8 1.2e-90 302.8 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EAQ87998.1 - 0.00027 20.7 0.0 5.9 7.2 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EAQ87998.1 - 0.15 11.9 0.1 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAQ87998.1 - 0.36 11.1 7.2 5.2 7.4 0.0 4.5 3 2 1 4 4 4 0 HEAT repeats RhoGAP PF00620.22 EAQ88000.1 - 3e-46 156.8 0.0 3e-46 156.8 0.0 2.8 2 2 1 3 3 3 1 RhoGAP domain LIM PF00412.17 EAQ88000.1 - 6.1e-14 51.8 19.3 5.3e-09 36.0 1.6 2.4 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 EAQ88000.1 - 5.6 6.9 17.3 0.73 9.8 0.8 4.0 4 0 0 4 4 4 0 Zinc ribbon domain PAT1 PF09770.4 EAQ88001.1 - 0.61 8.2 29.1 0.69 8.0 20.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EAQ88001.1 - 0.81 9.5 21.0 0.93 9.3 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4210 PF13915.1 EAQ88002.1 - 5.9e-25 87.3 0.1 1.9e-24 85.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EAQ88002.1 - 8.9e-21 73.5 0.7 2.2e-20 72.2 0.5 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis GTP_EFTU PF00009.22 EAQ88003.1 - 6.2e-60 201.8 0.0 8.6e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EAQ88003.1 - 8.3e-13 48.2 0.1 8.3e-13 48.2 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EAQ88003.1 - 3.8e-12 45.8 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EAQ88003.1 - 8e-12 44.7 0.0 2.5e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EAQ88003.1 - 1.8e-05 24.6 0.1 3.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 EAQ88004.1 - 2.6e-76 256.5 0.4 3.4e-76 256.1 0.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha tRNA_int_endo_N PF02778.9 EAQ88005.1 - 0.37 10.3 0.0 0.83 9.2 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Na_Ca_ex PF01699.19 EAQ88006.1 - 8.6e-41 138.8 36.6 1.3e-22 79.9 7.0 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3608 PF12257.3 EAQ88007.1 - 4.4e-74 248.8 0.0 7.3e-74 248.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EAQ88007.1 - 1.6e-31 107.8 0.2 3.7e-31 106.6 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.16 EAQ88008.1 - 3.7e-53 180.4 0.0 4.7e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family FNIP_N PF14636.1 EAQ88009.1 - 3.5e-24 85.7 5.6 1.8e-23 83.4 0.1 4.0 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.1 EAQ88009.1 - 0.0046 16.3 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_M PF14637.1 EAQ88009.1 - 0.19 11.2 0.0 0.6 9.6 0.0 1.8 1 1 0 1 1 1 0 Folliculin-interacting protein middle domain Lactonase PF10282.4 EAQ88010.1 - 5.7e-87 291.9 0.0 6.5e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.13 EAQ88012.1 - 4e-09 36.2 7.9 4e-09 36.2 5.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ88012.1 - 5.3e-08 32.0 0.2 5.3e-08 32.0 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2668 PF10873.3 EAQ88013.1 - 1.1 9.4 4.2 4.5 7.4 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) DEAD PF00270.24 EAQ88015.1 - 2.2e-46 157.4 0.1 1.3e-45 154.9 0.0 2.1 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ88015.1 - 6.3e-23 80.4 0.1 2.8e-22 78.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EAQ88015.1 - 1.8e-22 78.9 1.0 5.4e-22 77.3 0.7 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain SNF2_N PF00176.18 EAQ88015.1 - 0.0021 16.8 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EAQ88015.1 - 0.0061 16.4 0.1 0.029 14.1 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 EAQ88016.1 - 1.9e-14 53.1 0.8 5.9e-14 51.5 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain Daxx PF03344.10 EAQ88017.1 - 0.46 8.8 8.7 0.7 8.3 6.0 1.2 1 0 0 1 1 1 0 Daxx Family DUF202 PF02656.10 EAQ88019.1 - 5.8e-16 58.4 0.2 7.4e-16 58.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 EAQ88019.1 - 0.038 13.9 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV RPA_C PF08784.6 EAQ88020.1 - 1.5e-14 54.2 0.6 1.1e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EAQ88020.1 - 4.3e-07 29.6 0.2 6.8e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MarR_2 PF12802.2 EAQ88020.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 MarR family Serglycin PF04360.7 EAQ88021.1 - 0.98 9.1 4.5 1.7 8.3 3.1 1.3 1 0 0 1 1 1 0 Serglycin NUDIX PF00293.23 EAQ88022.1 - 1.6e-13 50.4 0.0 6.8e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain TraE PF05309.6 EAQ88022.1 - 0.0095 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 TraE protein MatE PF01554.13 EAQ88023.1 - 2.3e-47 160.6 16.8 1.3e-27 96.3 5.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EAQ88023.1 - 0.00023 20.9 20.8 0.027 14.2 5.7 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain ATP_synt_I PF03899.10 EAQ88023.1 - 0.0094 16.0 0.4 0.0094 16.0 0.3 3.9 4 1 0 4 4 4 1 ATP synthase I chain Npa1 PF11707.3 EAQ88024.1 - 4.6e-70 236.2 0.0 7.6e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DNA_mis_repair PF01119.14 EAQ88026.1 - 2.6e-35 120.4 0.1 4.7e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EAQ88027.1 - 2.1e-06 27.4 0.1 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAQ88027.1 - 4e-06 26.5 0.1 5.1e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.2 EAQ88029.1 - 0.0046 16.6 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Lon_C PF05362.8 EAQ88033.1 - 3.3e-66 222.5 0.4 5.7e-66 221.7 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EAQ88033.1 - 6.6e-26 91.2 0.0 1.1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EAQ88033.1 - 4.4e-23 81.9 0.0 8.8e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ88033.1 - 4.6e-09 36.1 0.0 2.7e-08 33.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EAQ88033.1 - 4.4e-08 32.6 0.0 1.3e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EAQ88033.1 - 3.2e-05 24.0 0.0 9.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.6 EAQ88033.1 - 0.00011 21.8 0.0 0.00032 20.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EAQ88033.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EAQ88033.1 - 0.00047 20.9 0.0 0.0013 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ88033.1 - 0.00085 19.4 0.0 0.0082 16.2 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EAQ88033.1 - 0.00086 19.2 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EAQ88033.1 - 0.0014 17.7 0.1 0.0043 16.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ88033.1 - 0.0014 18.3 0.1 0.0076 15.9 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EAQ88033.1 - 0.0035 16.7 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAQ88033.1 - 0.0046 16.8 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ88033.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EAQ88033.1 - 0.014 14.1 0.3 0.035 12.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus AAA_23 PF13476.1 EAQ88033.1 - 0.065 13.5 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EAQ88033.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ88033.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EAQ88033.1 - 0.095 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EAQ88033.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EAQ88033.1 - 0.13 11.4 0.1 0.26 10.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAQ88033.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MOR2-PAG1_N PF14222.1 EAQ88034.1 - 1.4e-225 750.2 0.0 2.1e-225 749.6 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EAQ88034.1 - 1.3e-97 326.6 0.2 3.4e-97 325.3 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EAQ88034.1 - 3.7e-32 110.9 3.8 3.3e-13 48.1 0.0 3.8 2 1 1 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.2 EAQ88034.1 - 2.3 8.0 5.2 1.7 8.4 0.1 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_1 PF00667.15 EAQ88035.1 - 1e-60 204.8 0.0 1.5e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EAQ88035.1 - 7.1e-34 116.8 0.3 1.5e-33 115.7 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EAQ88035.1 - 3.1e-15 56.6 0.1 2.6e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EAQ88035.1 - 0.0026 17.7 0.2 0.0091 15.9 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain RRM_1 PF00076.17 EAQ88036.1 - 3.3e-25 87.4 0.0 5.3e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ88036.1 - 1.3e-16 60.3 0.0 6.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ88036.1 - 4.7e-08 32.7 0.1 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4586 PF15239.1 EAQ88036.1 - 0.016 14.7 0.2 0.044 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) RIO1 PF01163.17 EAQ88037.1 - 1.5e-40 138.5 0.1 6.1e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EAQ88037.1 - 1.1e-31 108.6 0.1 2.8e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EAQ88037.1 - 3.4e-08 33.5 0.2 0.00025 20.8 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EAQ88037.1 - 1.3e-05 24.3 0.1 0.024 13.6 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma70_ner PF04546.8 EAQ88037.1 - 1.5 8.4 14.3 1.1 8.8 5.6 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region RXT2_N PF08595.6 EAQ88037.1 - 2.4 7.9 8.8 2.3 8.0 2.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF1840 PF08895.6 EAQ88037.1 - 3.7 7.6 5.6 6.5 6.8 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4484 PF14831.1 EAQ88037.1 - 4.4 7.3 7.9 13 5.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) FAM176 PF14851.1 EAQ88037.1 - 7.3 6.2 9.9 1.9 8.1 1.9 2.2 2 0 0 2 2 2 0 FAM176 family PC_rep PF01851.17 EAQ88038.1 - 5.1e-21 73.6 22.6 2.6e-07 30.5 0.1 9.4 10 0 0 10 10 10 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EAQ88038.1 - 3.3e-08 33.6 0.1 0.0015 18.7 0.1 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EAQ88038.1 - 0.046 14.2 0.5 1.2 9.7 0.1 3.3 2 1 1 3 3 3 0 HEAT-like repeat TPR_5 PF12688.2 EAQ88038.1 - 0.073 13.1 0.2 5.4 7.0 0.0 3.0 2 1 0 2 2 2 0 Tetratrico peptide repeat Sec1 PF00995.18 EAQ88039.1 - 1.7e-111 373.6 0.0 1.7e-89 301.0 0.0 2.0 1 1 1 2 2 2 2 Sec1 family Iso_dh PF00180.15 EAQ88040.1 - 5.5e-87 291.9 0.0 2.3e-65 220.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.8 EAQ88040.1 - 2.4 7.6 7.7 0.11 12.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Transp_cyt_pur PF02133.10 EAQ88041.1 - 8.7e-12 44.3 7.1 1.3e-11 43.7 4.4 1.5 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.14 EAQ88043.1 - 1.5e-17 63.6 0.2 1e-16 60.9 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ88043.1 - 4.5e-06 26.5 0.1 1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EAQ88043.1 - 0.00045 19.1 0.0 0.0009 18.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.2 EAQ88043.1 - 0.0023 17.0 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ88043.1 - 0.0042 15.9 1.1 0.017 13.9 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EAQ88043.1 - 0.0076 15.1 1.2 0.017 14.0 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ88043.1 - 0.012 15.4 1.5 0.022 14.6 1.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EAQ88043.1 - 0.014 15.1 0.3 0.74 9.6 0.1 2.6 3 0 0 3 3 3 0 ThiF family Thi4 PF01946.12 EAQ88043.1 - 0.036 13.1 0.2 0.096 11.7 0.1 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EAQ88043.1 - 0.05 13.6 0.1 0.081 12.9 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ88043.1 - 0.06 12.1 0.2 0.087 11.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EAQ88043.1 - 0.077 12.6 1.0 0.25 10.9 0.7 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EAQ88043.1 - 0.084 13.2 0.1 0.32 11.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EAQ88043.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EAQ88043.1 - 0.34 11.3 2.3 2.4 8.6 0.9 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF221 PF02714.10 EAQ88044.1 - 5e-57 193.2 21.0 1.4e-32 112.8 3.5 2.6 2 1 1 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAQ88044.1 - 1.1e-35 122.5 0.3 1.1e-35 122.5 0.2 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EAQ88044.1 - 3.5e-15 55.6 0.0 8.4e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EAQ88044.1 - 7.1e-09 36.0 2.1 0.0016 18.9 0.6 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) Hamartin PF04388.7 EAQ88047.1 - 2.8e-31 108.9 9.1 8.7e-31 107.3 6.3 2.0 1 1 0 1 1 1 1 Hamartin protein WEMBL PF05701.6 EAQ88047.1 - 0.66 8.3 40.4 0.11 10.8 21.1 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.6 EAQ88047.1 - 6.7 5.2 25.0 2.9 6.4 15.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.1 EAQ88047.1 - 7.3 6.5 33.1 0.33 10.8 9.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4066 PF13278.1 EAQ88048.1 - 1.1e-22 80.0 0.3 1.3e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ88048.1 - 0.00022 20.7 0.0 0.00059 19.3 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Metallophos_2 PF12850.2 EAQ88048.1 - 0.094 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.15 EAQ88049.1 - 2.3e-14 53.1 0.0 3.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.22 EAQ88050.1 - 1.2e-61 204.4 3.9 4.1e-20 71.2 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein SOG2 PF10428.4 EAQ88051.1 - 0.59 8.7 3.3 0.81 8.2 2.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1509 PF07420.6 EAQ88051.1 - 0.83 8.8 5.2 0.97 8.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SSP160 PF06933.6 EAQ88051.1 - 6.9 4.5 10.8 8.2 4.2 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EAQ88051.1 - 9.7 5.9 13.6 13 5.5 6.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) ORC4_C PF14629.1 EAQ88052.1 - 7.3e-57 192.0 0.0 1.1e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EAQ88052.1 - 5.8e-16 59.0 0.2 8.4e-15 55.2 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.1 EAQ88052.1 - 3.1e-12 45.5 2.8 5.9e-12 44.6 2.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 EAQ88052.1 - 6.3e-11 41.7 7.1 1.2e-10 40.8 4.9 1.5 1 0 0 1 1 1 1 PHD-finger AAA PF00004.24 EAQ88052.1 - 1.7e-08 34.6 0.0 4.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EAQ88052.1 - 3e-08 33.4 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ88052.1 - 1.2e-07 31.9 0.1 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAQ88052.1 - 1.6e-05 24.7 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 EAQ88052.1 - 8.2e-05 21.7 0.0 0.00024 20.2 0.0 1.6 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.17 EAQ88052.1 - 0.0004 19.3 0.1 0.00061 18.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EAQ88052.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAQ88052.1 - 0.00058 19.4 1.2 0.0019 17.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain FYVE_2 PF02318.11 EAQ88052.1 - 0.0019 18.1 0.5 0.0038 17.1 0.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger ATP-synt_ab PF00006.20 EAQ88052.1 - 0.002 17.6 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EAQ88052.1 - 0.0032 16.9 0.2 0.047 13.1 0.0 2.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family C1_1 PF00130.17 EAQ88052.1 - 0.0058 16.3 0.5 0.011 15.4 0.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ABC_tran PF00005.22 EAQ88052.1 - 0.0062 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Prok-RING_1 PF14446.1 EAQ88052.1 - 0.0062 16.2 2.7 0.013 15.2 1.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PduV-EutP PF10662.4 EAQ88052.1 - 0.0088 15.5 0.2 0.044 13.2 0.1 2.1 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EAQ88052.1 - 0.0088 16.8 0.0 0.028 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EAQ88052.1 - 0.0091 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EAQ88052.1 - 0.01 15.2 0.2 0.67 9.3 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EAQ88052.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EAQ88052.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EAQ88052.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAQ88052.1 - 0.036 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EAQ88052.1 - 0.038 14.4 0.0 0.09 13.2 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein Septin PF00735.13 EAQ88052.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin PIF1 PF05970.9 EAQ88052.1 - 0.11 11.4 0.1 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Bac_DnaA PF00308.13 EAQ88052.1 - 0.13 11.8 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein cobW PF02492.14 EAQ88052.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EAQ88052.1 - 0.14 11.8 0.2 0.39 10.4 0.0 1.8 3 0 0 3 3 1 0 NTPase zf-PHD-like PF15446.1 EAQ88052.1 - 0.22 10.8 4.5 0.32 10.2 0.6 2.5 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain DZR PF12773.2 EAQ88052.1 - 2.4 8.0 6.0 6.8 6.6 4.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon Glyco_hydro_18 PF00704.23 EAQ88055.1 - 1.4e-52 179.2 0.2 1.8e-52 178.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RGS PF00615.14 EAQ88058.1 - 9.9e-38 128.8 0.6 4.9e-37 126.6 0.0 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EAQ88058.1 - 3.8e-22 77.7 0.1 8e-18 63.9 0.0 3.4 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_3 PF01381.17 EAQ88058.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Pkinase PF00069.20 EAQ88059.1 - 7.6e-09 35.0 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88059.1 - 2.5e-05 23.5 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ88059.1 - 0.00064 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EAQ88059.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EAQ88059.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sporozoite_P67 PF05642.6 EAQ88060.1 - 0.082 10.7 15.5 0.021 12.7 8.6 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_S64 PF08192.6 EAQ88060.1 - 4 5.6 4.8 5 5.3 3.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 EAQ88060.1 - 4.3 5.5 5.8 5.5 5.1 4.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 EAQ88060.1 - 6.2 5.0 7.6 7.6 4.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC73 PF05179.9 EAQ88061.1 - 1.6e-40 139.2 0.0 3.2e-40 138.2 0.0 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Bystin PF05291.6 EAQ88062.1 - 1.1e-95 320.0 0.0 5.7e-90 301.3 0.0 2.1 1 1 1 2 2 2 2 Bystin DUF383 PF04063.9 EAQ88063.1 - 7.2e-62 208.3 0.1 1.5e-61 207.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EAQ88063.1 - 5.7e-26 89.8 0.3 1.1e-25 88.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Sugar_tr PF00083.19 EAQ88064.1 - 2e-43 148.6 18.4 2.7e-43 148.1 12.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ88064.1 - 4.7e-20 71.6 24.9 6.9e-20 71.0 17.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA-Thr_ED PF08915.6 EAQ88064.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Fungal_trans PF04082.13 EAQ88065.1 - 9.1e-30 103.3 0.0 1.5e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88065.1 - 3.3e-09 36.5 9.4 5.3e-09 35.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EAQ88065.1 - 5 5.2 23.5 7.2 4.7 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 EAQ88066.1 - 9.1e-25 87.1 24.1 2.1e-16 59.5 2.5 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88066.1 - 2.4e-09 36.3 1.6 2.4e-09 36.3 1.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EAQ88066.1 - 0.0015 17.0 1.8 0.0015 17.0 1.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Filaggrin PF03516.8 EAQ88068.1 - 0.18 12.2 2.8 0.24 11.9 1.9 1.2 1 0 0 1 1 1 0 Filaggrin DUF1014 PF06244.7 EAQ88070.1 - 1.4e-22 80.2 6.3 1.4e-22 80.2 4.4 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) UQ_con PF00179.21 EAQ88071.1 - 3.4e-08 33.0 0.0 5.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2OG-FeII_Oxy_2 PF13532.1 EAQ88072.1 - 2.4e-36 125.3 0.1 3.1e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EAQ88072.1 - 2.4e-10 40.1 2.4 5.2e-10 39.0 1.6 1.6 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EAQ88072.1 - 5.6e-05 23.3 0.1 0.00011 22.3 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EAQ88072.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 CUE domain WD40 PF00400.27 EAQ88073.1 - 1.2e-28 97.9 16.1 6.4e-10 38.5 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Helicase_C PF00271.26 EAQ88074.1 - 5e-21 74.3 0.1 1e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ88074.1 - 1.5e-16 60.3 0.0 4.1e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase NOT2_3_5 PF04153.13 EAQ88076.1 - 1.8e-29 102.3 0.5 1.8e-29 102.3 0.3 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family cobW PF02492.14 EAQ88076.1 - 3.2e-25 88.5 0.1 5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CUE PF02845.11 EAQ88076.1 - 2e-10 39.9 0.0 3.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain AflR PF08493.5 EAQ88076.1 - 4.1 6.3 6.2 11 4.9 4.3 1.7 1 0 0 1 1 1 0 Aflatoxin regulatory protein Mob1_phocein PF03637.12 EAQ88077.1 - 2e-24 86.2 0.1 3.1e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.3 EAQ88078.1 - 2.5e-13 49.3 0.9 1.1e-12 47.2 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88078.1 - 8.1e-07 28.8 11.7 1.4e-06 28.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC PF03473.12 EAQ88081.1 - 9.9e-14 50.9 0.0 2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EAQ88081.1 - 1.3e-11 44.2 0.0 4.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain DUF4653 PF15546.1 EAQ88081.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) NapE PF06796.6 EAQ88081.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.2 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE SMC_N PF02463.14 EAQ88082.1 - 2.8e-68 229.4 18.7 1.3e-38 132.4 0.4 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAQ88082.1 - 9.5e-23 80.4 0.7 6.7e-22 77.7 0.2 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EAQ88082.1 - 4.9e-14 53.1 13.9 4.9e-14 53.1 9.6 5.5 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 EAQ88082.1 - 1.2e-13 51.6 2.1 5.4e-06 26.5 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAQ88082.1 - 7.9e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EAQ88082.1 - 0.98 8.5 29.0 0.092 11.9 1.0 6.0 4 2 3 7 7 7 0 Reovirus sigma C capsid protein Arv1 PF04161.8 EAQ88084.1 - 2.7e-37 128.7 0.0 3.5e-18 66.2 0.0 2.1 1 1 1 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 EAQ88085.1 - 2.1e-26 91.7 2.4 2.4e-26 91.5 1.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 EAQ88085.1 - 0.019 14.3 1.2 0.02 14.2 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YfhO PF09586.5 EAQ88085.1 - 0.023 12.7 0.2 0.023 12.7 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HlyIII PF03006.15 EAQ88085.1 - 0.032 13.6 0.6 0.033 13.5 0.4 1.0 1 0 0 1 1 1 0 Haemolysin-III related DUF2142 PF09913.4 EAQ88085.1 - 0.036 12.7 0.4 0.038 12.6 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF1129 PF06570.6 EAQ88085.1 - 0.069 12.4 0.2 0.081 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MgtE PF01769.11 EAQ88085.1 - 0.09 13.0 0.6 0.11 12.8 0.4 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF4231 PF14015.1 EAQ88085.1 - 0.16 11.9 1.5 0.19 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) ABC2_membrane_4 PF12730.2 EAQ88085.1 - 0.18 10.9 4.0 0.24 10.5 2.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1772 PF08592.6 EAQ88085.1 - 0.27 10.9 2.3 0.29 10.8 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) ABC2_membrane_2 PF12679.2 EAQ88085.1 - 0.4 9.5 3.2 0.45 9.3 2.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein BCD PF15461.1 EAQ88085.1 - 9.5 5.5 8.2 5.4 6.3 1.5 2.0 1 1 1 2 2 2 0 Beta-carotene 15,15'-dioxygenase NAD_binding_2 PF03446.10 EAQ88086.1 - 1.1e-22 80.6 0.2 1.8e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EAQ88086.1 - 2.7e-08 33.8 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EAQ88086.1 - 0.0021 18.1 0.6 0.0021 18.1 0.4 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EAQ88086.1 - 0.021 15.2 3.3 0.022 15.1 1.2 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_C53 PF05550.6 EAQ88086.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 BAR_2 PF10455.4 EAQ88087.1 - 1e-56 191.9 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EAQ88087.1 - 3.1e-20 72.6 0.1 2.9e-19 69.5 0.1 1.9 1 1 0 1 1 1 1 BAR domain LSM PF01423.17 EAQ88088.1 - 3.2e-16 58.6 0.0 4.1e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 EAQ88088.1 - 0.71 10.3 20.6 1.1 9.7 14.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family RAM PF15320.1 EAQ88088.1 - 2.8 8.2 10.6 3.7 7.8 7.4 1.2 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein PPR_3 PF13812.1 EAQ88089.1 - 1.2e-11 43.9 5.5 0.047 13.9 0.0 8.0 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 EAQ88089.1 - 5.3e-11 41.7 1.3 0.98 9.5 0.0 6.6 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.1 EAQ88089.1 - 7.6e-10 38.6 0.1 0.0042 17.0 0.0 6.6 7 1 1 8 8 8 2 PPR repeat family PPR_1 PF12854.2 EAQ88089.1 - 0.00018 20.9 0.0 6.2 6.3 0.0 4.4 4 0 0 4 4 4 2 PPR repeat MFS_1 PF07690.11 EAQ88090.1 - 3.5e-29 101.6 25.5 1.8e-22 79.5 7.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88090.1 - 2.3e-08 33.0 0.9 2.3e-08 33.0 0.6 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.5 EAQ88090.1 - 0.011 16.0 0.6 0.011 16.0 0.4 2.5 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) HIT PF01230.18 EAQ88091.1 - 5.3e-21 74.9 0.1 8.4e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EAQ88091.1 - 0.0009 19.4 0.0 0.8 9.9 0.0 2.1 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding Fungal_trans PF04082.13 EAQ88092.1 - 2.3e-43 147.9 0.0 3.5e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88092.1 - 2.1e-08 33.9 7.0 4.4e-08 32.8 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferrochelatase PF00762.14 EAQ88093.1 - 8e-92 307.5 0.0 9.2e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku_N PF03731.10 EAQ88094.1 - 1e-35 123.2 0.0 1.4e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EAQ88094.1 - 6e-22 78.0 0.0 4.6e-16 58.8 0.0 2.4 1 1 1 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EAQ88094.1 - 1.3e-13 51.3 0.1 4.3e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EAQ88094.1 - 1.6e-11 43.4 0.2 2.9e-10 39.3 0.2 2.3 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 EAQ88094.1 - 8.3e-05 22.0 0.6 0.00028 20.3 0.4 2.0 1 1 0 1 1 1 1 HeH/LEM domain VWA_2 PF13519.1 EAQ88094.1 - 0.00063 19.8 0.1 0.0011 19.0 0.1 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EAQ88094.1 - 0.014 15.1 0.0 0.063 13.0 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain LETM1 PF07766.8 EAQ88094.1 - 0.19 10.7 0.2 0.33 9.9 0.1 1.3 1 0 0 1 1 1 0 LETM1-like protein Zn_clus PF00172.13 EAQ88095.1 - 9.6e-05 22.2 7.8 0.00018 21.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain La PF05383.12 EAQ88096.1 - 2e-16 59.4 0.0 3.1e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 La domain S4 PF01479.20 EAQ88097.1 - 1.3e-16 59.7 0.0 2.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EAQ88097.1 - 0.0014 18.1 0.0 0.005 16.4 0.0 1.9 2 0 0 2 2 2 1 S4 domain Lumazine_bd PF12870.2 EAQ88097.1 - 0.032 14.2 2.2 0.067 13.2 1.5 1.7 1 0 0 1 1 1 0 Lumazine-binding domain Vfa1 PF08432.5 EAQ88097.1 - 9.5 6.1 10.5 2.4 8.1 5.0 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Septin PF00735.13 EAQ88098.1 - 1.9e-122 407.7 0.3 1.9e-122 407.7 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EAQ88098.1 - 3.1e-07 30.3 0.0 7.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAQ88098.1 - 6.3e-06 25.7 0.1 0.00033 20.1 0.0 2.8 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EAQ88098.1 - 4.9e-05 22.5 0.4 0.00035 19.8 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EAQ88098.1 - 6.6e-05 22.4 0.2 0.0015 18.0 0.1 2.3 2 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EAQ88098.1 - 0.00031 21.0 2.9 0.015 15.6 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EAQ88098.1 - 0.00053 19.1 0.8 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EAQ88098.1 - 0.00054 20.4 0.2 0.0028 18.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EAQ88098.1 - 0.0021 18.0 0.1 0.012 15.6 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAQ88098.1 - 0.0023 18.0 0.0 0.021 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EAQ88098.1 - 0.0027 17.1 0.1 0.019 14.4 0.0 2.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family Ras PF00071.17 EAQ88098.1 - 0.0038 16.6 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.1 EAQ88098.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EAQ88098.1 - 0.018 14.5 0.6 3.6 7.0 0.0 3.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EAQ88098.1 - 0.019 15.1 0.9 0.32 11.1 0.0 2.6 3 0 0 3 3 2 0 RNA helicase MobB PF03205.9 EAQ88098.1 - 0.036 13.7 1.9 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EAQ88098.1 - 0.044 13.6 8.6 0.5 10.1 0.1 3.7 3 2 0 4 4 4 0 Dynamin family Exonuc_VII_L PF02601.10 EAQ88098.1 - 0.056 12.6 5.3 0.12 11.5 3.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sigma54_activat PF00158.21 EAQ88098.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EAQ88098.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAQ88098.1 - 0.073 12.4 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAQ88098.1 - 1.4 8.6 5.1 2.2 8.0 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 IncA PF04156.9 EAQ88098.1 - 3 7.4 9.6 4.8 6.7 6.6 1.3 1 0 0 1 1 1 0 IncA protein PLA2_B PF01735.13 EAQ88099.1 - 5.2e-29 100.7 0.0 9.7e-29 99.8 0.0 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Ribonucleas_3_3 PF14622.1 EAQ88100.1 - 0.0022 17.9 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EAQ88100.1 - 0.0049 17.4 0.0 0.0083 16.6 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EAQ88100.1 - 0.029 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain Metallophos PF00149.23 EAQ88102.1 - 1.2e-08 34.5 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Resistin PF06954.6 EAQ88102.1 - 0.044 14.0 0.7 0.1 12.8 0.5 1.6 1 0 0 1 1 1 0 Resistin Cyclin_N PF00134.18 EAQ88103.1 - 0.0056 16.2 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain OTCace_N PF02729.16 EAQ88108.1 - 3.8e-42 143.3 0.0 8.1e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EAQ88108.1 - 3.6e-35 121.1 0.0 1e-34 119.7 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_D2 PF02786.12 EAQ88108.1 - 5.4e-28 97.7 0.1 8.4e-28 97.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EAQ88108.1 - 1.2e-24 87.0 0.1 3.1e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain MGS PF02142.17 EAQ88108.1 - 1.1e-21 76.5 0.0 4.7e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 EAQ88108.1 - 3.2e-13 49.1 0.2 2.9e-12 45.9 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EAQ88108.1 - 2.9e-10 39.7 0.1 5.2e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAQ88108.1 - 2.2e-09 36.9 0.1 5.6e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EAQ88108.1 - 0.004 17.0 0.1 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF992 PF06186.6 EAQ88108.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) CPSase_L_D2 PF02786.12 EAQ88109.1 - 1.6e-84 282.4 0.0 2.4e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EAQ88109.1 - 4.7e-44 149.0 0.0 9.2e-44 148.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EAQ88109.1 - 7.3e-44 149.5 0.0 1.2e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 EAQ88109.1 - 5e-41 139.3 0.0 1.4e-40 137.8 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EAQ88109.1 - 1.7e-23 82.8 0.2 2.2e-18 66.3 0.0 2.8 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EAQ88109.1 - 1.5e-11 44.3 0.0 5.8e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Peptidase_C26 PF07722.8 EAQ88109.1 - 2.5e-06 27.1 0.3 0.00023 20.6 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp PF02222.17 EAQ88109.1 - 2.7e-06 26.8 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAQ88109.1 - 2.9e-06 26.8 0.0 6.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DJ-1_PfpI PF01965.19 EAQ88109.1 - 0.00089 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family ATP-grasp_3 PF02655.9 EAQ88109.1 - 0.055 13.3 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain TAP42 PF04177.7 EAQ88113.1 - 1.3e-106 356.3 0.0 1.5e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family PNPOx_C PF10590.4 EAQ88114.1 - 2e-21 75.1 2.5 6.2e-21 73.6 1.8 1.9 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EAQ88114.1 - 2.2e-11 43.5 0.0 1.4e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EAQ88114.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribonuclease_3 PF00636.21 EAQ88115.1 - 2e-28 99.1 0.3 1.9e-17 63.7 0.0 4.1 3 1 0 4 4 4 3 Ribonuclease III domain Dicer_dimer PF03368.9 EAQ88115.1 - 3.8e-21 74.6 0.6 1.7e-19 69.3 0.1 3.1 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 EAQ88115.1 - 3.6e-19 68.9 0.0 2.8e-09 37.0 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 EAQ88115.1 - 3.8e-14 52.3 0.0 8.9e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ88115.1 - 0.00071 19.4 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EAQ88115.1 - 0.011 16.2 0.9 2.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif DEAD PF00270.24 EAQ88115.1 - 0.022 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Peptidase_C12 PF01088.16 EAQ88117.1 - 6.5e-59 198.6 0.0 7.7e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.3 EAQ88118.1 - 7.4e-17 60.5 1.0 1.5e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EAQ88118.1 - 2.3e-08 33.8 0.0 5.7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Synaptobrevin PF00957.16 EAQ88119.1 - 1.8e-29 101.1 0.1 2.4e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EAQ88119.1 - 6.4e-22 76.9 0.0 9.8e-22 76.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.20 EAQ88120.1 - 5.4e-12 45.9 0.3 5.4e-12 45.9 0.2 2.9 2 2 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EAQ88120.1 - 2.5e-07 30.5 1.4 7.9e-07 28.9 0.0 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EAQ88120.1 - 0.0066 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family E1-N PF14463.1 EAQ88120.1 - 0.023 14.2 0.3 0.13 11.8 0.1 2.2 1 1 1 2 2 2 0 E1 N-terminal domain G-patch PF01585.18 EAQ88121.1 - 5.7e-09 35.6 0.1 1e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EAQ88121.1 - 0.016 15.0 0.2 0.33 10.8 0.1 2.5 2 0 0 2 2 2 0 DExH-box splicing factor binding site DUF2685 PF10886.3 EAQ88121.1 - 0.039 13.9 0.5 0.091 12.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) Sec63 PF02889.11 EAQ88122.1 - 9.2e-141 468.5 0.0 2e-94 316.3 0.1 2.7 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EAQ88122.1 - 9.5e-52 174.8 0.1 2.7e-27 95.3 0.2 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ88122.1 - 4.3e-16 58.5 0.0 1.1e-06 28.3 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ88122.1 - 4.1e-15 56.0 0.0 1.9e-06 27.8 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAQ88122.1 - 4.1e-07 30.1 0.1 0.04 14.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EAQ88122.1 - 1.4e-05 24.7 0.6 0.029 14.1 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 EAQ88122.1 - 2.5e-05 23.2 0.2 0.11 11.2 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_25 PF13481.1 EAQ88122.1 - 0.0046 16.3 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EAQ88122.1 - 0.0057 16.8 4.2 2.4 8.3 0.0 4.9 4 2 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EAQ88122.1 - 0.014 14.7 0.0 18 4.6 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAQ88122.1 - 0.1 11.7 0.1 3.3 6.7 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin Ras PF00071.17 EAQ88123.1 - 4.9e-65 217.8 0.1 5.8e-65 217.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ88123.1 - 1.5e-19 70.6 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ88123.1 - 2.1e-13 49.8 0.0 2.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ88123.1 - 1.4e-06 27.9 0.1 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ88123.1 - 6.3e-06 25.5 0.0 7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ88123.1 - 0.0043 16.9 0.0 0.0059 16.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAQ88123.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EAQ88123.1 - 0.045 13.0 0.0 0.21 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 EAQ88123.1 - 0.073 11.7 0.8 8.9 4.8 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 EAQ88123.1 - 0.092 12.2 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EAQ88123.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.5 EAQ88124.1 - 2.7e-90 302.1 0.3 4.3e-90 301.5 0.2 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 EAQ88125.1 - 1.8e-08 34.7 4.6 1.8e-08 34.7 3.2 3.0 2 1 1 3 3 3 2 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 EAQ88126.1 - 9.6e-27 92.5 0.1 1.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PKI PF02827.11 EAQ88126.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor bZIP_1 PF00170.16 EAQ88127.1 - 0.76 9.7 6.0 12 5.9 4.1 2.1 1 1 0 1 1 1 0 bZIP transcription factor Actin PF00022.14 EAQ88128.1 - 1.9e-48 164.8 0.0 3.9e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 Actin Pkinase PF00069.20 EAQ88129.1 - 0.00074 18.7 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88129.1 - 0.0039 16.3 0.0 0.0064 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.3 EAQ88129.1 - 0.044 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 YL1_C PF08265.6 EAQ88130.1 - 9.5e-17 60.2 0.0 1.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF3580 PF12117.3 EAQ88130.1 - 0.038 13.9 1.4 0.051 13.5 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3580) Got1 PF04178.7 EAQ88131.1 - 2.4e-19 69.5 11.2 2.8e-19 69.3 7.8 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 EAQ88131.1 - 1.9 8.1 8.6 0.17 11.5 2.3 2.0 2 0 0 2 2 2 0 YrhK-like protein Profilin PF00235.14 EAQ88132.1 - 2.3e-34 118.1 0.5 2.6e-34 117.9 0.3 1.0 1 0 0 1 1 1 1 Profilin AAA PF00004.24 EAQ88134.1 - 1.8e-53 180.2 0.0 6.8e-39 133.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ88134.1 - 4.5e-10 39.8 0.3 4.9e-05 23.3 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 EAQ88134.1 - 5.8e-06 26.3 0.0 0.00065 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAQ88134.1 - 1.6e-05 24.4 3.9 0.45 9.8 0.0 4.1 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 EAQ88134.1 - 9.1e-05 22.2 0.1 0.031 13.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EAQ88134.1 - 0.00014 21.7 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EAQ88134.1 - 0.00061 19.4 0.5 0.56 9.9 0.1 3.6 2 1 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EAQ88134.1 - 0.00097 18.2 0.0 0.048 12.6 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EAQ88134.1 - 0.0033 17.5 0.0 4.7 7.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.1 EAQ88134.1 - 0.0049 17.0 8.7 1.4 9.1 0.1 4.7 3 2 2 5 5 5 1 AAA domain AAA_2 PF07724.9 EAQ88134.1 - 0.0078 16.1 0.0 0.15 11.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EAQ88134.1 - 0.0089 15.7 5.0 0.48 10.0 2.3 3.4 2 1 0 2 2 2 1 NACHT domain AFG1_ATPase PF03969.11 EAQ88134.1 - 0.017 13.9 0.0 0.13 11.0 0.0 2.3 3 0 0 3 3 3 0 AFG1-like ATPase AAA_33 PF13671.1 EAQ88134.1 - 0.019 14.8 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EAQ88134.1 - 0.037 14.8 0.2 3.3 8.5 0.1 2.9 2 2 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EAQ88134.1 - 0.04 13.3 0.0 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 EAQ88134.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Mg_chelatase PF01078.16 EAQ88134.1 - 0.048 12.8 1.4 0.69 9.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 EAQ88134.1 - 0.054 12.1 0.0 0.097 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Vps4_C PF09336.5 EAQ88134.1 - 0.07 13.0 0.0 0.62 10.0 0.0 2.7 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 EAQ88134.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EAQ88134.1 - 0.12 11.0 0.1 2.7 6.6 0.0 2.4 3 0 0 3 3 3 0 TIP49 C-terminus DAP3 PF10236.4 EAQ88134.1 - 0.19 10.6 0.3 4.1 6.2 0.1 2.6 2 1 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 EAQ88134.1 - 0.2 10.7 2.0 0.85 8.6 0.1 2.5 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.13 EAQ88134.1 - 0.48 10.0 1.9 4.2 6.9 1.3 2.3 1 1 0 1 1 1 0 Bacterial dnaA protein KAP_NTPase PF07693.9 EAQ88134.1 - 0.95 8.3 2.2 8.5 5.2 0.2 2.2 2 0 0 2 2 2 0 KAP family P-loop domain SMK-1 PF04802.10 EAQ88135.1 - 3.9e-77 258.1 0.6 3.9e-77 258.1 0.4 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 TSA PF03249.8 EAQ88135.1 - 0.0042 15.6 2.1 0.0042 15.6 1.4 1.6 2 0 0 2 2 2 1 Type specific antigen Ribosomal_60s PF00428.14 EAQ88135.1 - 0.0047 17.2 10.7 0.0054 17.1 5.7 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF3978 PF13123.1 EAQ88135.1 - 0.096 12.0 0.1 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) DUF2360 PF10152.4 EAQ88135.1 - 4.3 7.6 10.2 8 6.7 3.7 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Glycos_transf_2 PF00535.21 EAQ88138.1 - 3.4e-23 82.1 0.0 5.3e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EAQ88138.1 - 1.5e-09 38.0 0.0 1.1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 SE PF08491.5 EAQ88139.1 - 1.2e-81 273.6 0.0 1.9e-81 272.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EAQ88139.1 - 5.8e-14 51.9 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ88139.1 - 2.7e-08 33.1 1.2 8.4e-08 31.5 0.2 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EAQ88139.1 - 1.9e-06 27.2 0.3 2.5e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EAQ88139.1 - 3.1e-06 26.3 0.0 6.8e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EAQ88139.1 - 3.4e-05 23.7 0.2 8.1e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ88139.1 - 6.3e-05 21.9 0.4 0.0001 21.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ88139.1 - 0.00014 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ88139.1 - 0.00025 20.2 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EAQ88139.1 - 0.0015 17.4 0.4 0.87 8.4 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 EAQ88139.1 - 0.0032 17.8 0.1 0.0076 16.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EAQ88139.1 - 0.0054 16.1 0.1 0.0096 15.3 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EAQ88139.1 - 0.034 13.8 0.1 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EAQ88139.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EAQ88139.1 - 0.04 12.4 0.1 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 EAQ88139.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EAQ88139.1 - 0.066 11.8 0.1 0.83 8.2 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.16 EAQ88139.1 - 0.2 11.4 0.4 0.36 10.6 0.2 1.4 1 0 0 1 1 1 0 ThiF family Peptidase_S26 PF10502.4 EAQ88142.1 - 2e-05 24.1 0.0 0.00021 20.8 0.0 2.0 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EAQ88142.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like EIF_2_alpha PF07541.7 EAQ88143.1 - 2.1e-37 127.3 0.0 4.1e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EAQ88143.1 - 3.1e-13 49.6 0.7 5.2e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.24 EAQ88144.1 - 2e-38 130.1 1.2 1.4e-19 69.6 0.0 5.1 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EAQ88144.1 - 1.6e-15 57.5 1.4 3.9e-15 56.3 0.4 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1625 PF07787.7 EAQ88144.1 - 6.5 5.9 6.4 44 3.2 5.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Pyridoxal_deC PF00282.14 EAQ88145.1 - 5.7e-108 360.6 0.0 8.1e-108 360.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.7 EAQ88146.1 - 2.8e-124 415.2 2.7 3.6e-124 414.8 1.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel FA_desaturase PF00487.19 EAQ88146.1 - 0.94 8.8 16.8 0.022 14.2 3.5 2.8 3 0 0 3 3 3 0 Fatty acid desaturase FMN_dh PF01070.13 EAQ88148.1 - 2.5e-119 398.2 0.4 3.2e-119 397.9 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EAQ88148.1 - 3.6e-24 84.3 0.0 7.5e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EAQ88148.1 - 1.9e-07 30.3 0.1 2.9e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EAQ88148.1 - 0.00013 21.2 0.2 0.0002 20.6 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAQ88148.1 - 0.00047 19.1 0.9 0.0011 17.9 0.1 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EAQ88148.1 - 0.002 17.4 0.8 0.17 11.1 0.0 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EAQ88148.1 - 0.078 12.0 0.1 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ras PF00071.17 EAQ88149.1 - 8.9e-16 57.6 0.2 2.5e-13 49.7 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAQ88149.1 - 2.5e-07 31.2 0.1 3.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein DUF2411 PF10304.4 EAQ88149.1 - 0.047 13.2 0.3 0.079 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Arf PF00025.16 EAQ88149.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.1 EAQ88149.1 - 0.075 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAQ88149.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAQ88149.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EAQ88149.1 - 0.17 11.3 0.3 3.2 7.2 0.1 2.1 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Borrelia_P83 PF05262.6 EAQ88150.1 - 2.7 6.1 33.3 3.8 5.6 23.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Arabinose_bd PF12625.2 EAQ88151.1 - 0.00053 19.8 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term COG2 PF06148.6 EAQ88151.1 - 0.086 12.7 1.2 0.69 9.7 0.2 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.8 EAQ88151.1 - 0.1 12.9 4.3 0.1 12.9 1.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) 2OG-FeII_Oxy_3 PF13640.1 EAQ88152.1 - 2.7e-10 40.6 0.0 5.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EAQ88152.1 - 6.7e-07 28.8 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Curto_V3 PF07436.6 EAQ88153.1 - 0.15 12.1 0.5 0.25 11.5 0.3 1.3 1 0 0 1 1 1 0 Curtovirus V3 protein HTH_Tnp_Tc5 PF03221.11 EAQ88154.1 - 2.7e-18 65.5 1.0 4.6e-06 26.3 0.0 5.7 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 EAQ88154.1 - 2.4e-12 46.3 0.0 1.4e-11 43.8 0.0 2.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EAQ88154.1 - 1.4e-05 24.6 0.4 3.8e-05 23.2 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EAQ88154.1 - 6.9e-05 22.8 15.0 0.013 15.8 2.9 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ88154.1 - 0.00043 20.4 13.1 0.029 14.6 2.6 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 EAQ88154.1 - 1.8 7.9 6.8 4.9 6.5 0.2 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_2 PF13465.1 EAQ88154.1 - 2 8.8 9.2 0.67 10.3 2.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Mucin PF01456.12 EAQ88154.1 - 2.3 7.9 17.8 2.6 7.8 7.1 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Elf1 PF05129.8 EAQ88154.1 - 3 7.5 6.5 3 7.6 3.2 2.1 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Nipped-B_C PF12830.2 EAQ88155.1 - 8.3e-47 159.2 2.0 5.3e-46 156.6 0.6 2.9 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EAQ88155.1 - 5.2e-11 42.2 1.0 5.2e-11 42.2 0.7 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EAQ88155.1 - 7e-08 31.9 1.3 0.21 11.7 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EAQ88155.1 - 3.5e-05 23.7 2.2 0.019 14.8 0.0 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.13 EAQ88156.1 - 6.8e-12 44.8 3.5 6.8e-12 44.8 2.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EAQ88156.1 - 9.7e-06 25.1 3.2 9.7e-06 25.1 2.2 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 EAQ88156.1 - 0.017 14.8 7.8 0.023 14.4 0.8 2.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 EAQ88156.1 - 0.022 14.2 12.4 1 8.9 0.4 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EAQ88156.1 - 0.041 14.1 9.7 0.12 12.6 0.2 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-ISL3 PF14690.1 EAQ88156.1 - 0.12 12.4 9.7 0.87 9.6 0.1 3.3 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 tRNA-synt_1f PF01921.13 EAQ88156.1 - 0.13 10.8 0.8 0.14 10.7 0.1 1.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.5 EAQ88156.1 - 0.25 11.3 0.1 0.25 11.3 0.1 3.2 3 1 0 3 3 2 0 Zinc ribbon domain zf-LITAF-like PF10601.4 EAQ88156.1 - 0.53 10.1 4.4 7.2 6.5 0.9 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DZR PF12773.2 EAQ88156.1 - 0.69 9.7 12.4 13 5.7 6.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 EAQ88156.1 - 0.9 9.8 13.7 5.1 7.4 1.9 3.3 1 1 2 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.1 EAQ88156.1 - 1.5 9.3 0.1 1.5 9.3 0.1 2.9 4 0 0 4 4 3 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.6 EAQ88156.1 - 1.5 8.5 12.9 1.4 8.6 1.0 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain IBR PF01485.16 EAQ88156.1 - 1.7 8.5 8.8 2.6 8.0 0.7 2.3 2 0 0 2 2 2 0 IBR domain TerY-C PF15616.1 EAQ88156.1 - 2.6 7.9 7.1 0.85 9.5 0.4 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain HypA PF01155.14 EAQ88156.1 - 3.7 7.2 10.6 3.4 7.4 1.5 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family HEAT_2 PF13646.1 EAQ88157.1 - 9e-29 99.6 3.9 1e-15 57.7 0.2 3.5 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.11 EAQ88157.1 - 3.5e-19 67.2 7.0 0.0052 17.1 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EAQ88157.1 - 1.1e-10 41.6 7.6 0.00032 21.0 0.1 4.8 3 2 2 5 5 5 2 HEAT-like repeat HEAT PF02985.17 EAQ88157.1 - 1.9e-06 27.4 6.4 0.68 10.1 0.0 5.9 7 0 0 7 7 7 2 HEAT repeat Cohesin_HEAT PF12765.2 EAQ88157.1 - 0.11 12.4 0.2 0.76 9.8 0.0 2.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF4448 PF14610.1 EAQ88158.1 - 0.0028 17.1 0.2 0.0046 16.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 EAQ88158.1 - 0.0048 15.2 0.3 0.0048 15.2 0.2 1.8 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E CDC45 PF02724.9 EAQ88158.1 - 0.0062 14.6 0.5 0.0079 14.2 0.4 1.1 1 0 0 1 1 1 1 CDC45-like protein SKG6 PF08693.5 EAQ88158.1 - 0.0071 15.6 1.2 0.019 14.2 0.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF912 PF06024.7 EAQ88158.1 - 0.0076 16.2 13.3 0.077 13.0 9.2 2.2 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EAQ88158.1 - 0.032 13.8 0.2 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Tetraspannin PF00335.15 EAQ88158.1 - 0.046 12.9 0.1 0.074 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetraspanin family Claudin_2 PF13903.1 EAQ88158.1 - 0.091 12.4 1.0 0.15 11.7 0.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Peptidase_M56 PF05569.6 EAQ88158.1 - 0.18 10.7 0.1 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.1 EAQ88158.1 - 0.19 12.1 0.3 0.19 12.1 0.2 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ABC2_membrane_3 PF12698.2 EAQ88158.1 - 0.2 10.6 2.6 0.29 10.1 1.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SAPS PF04499.10 EAQ88158.1 - 0.22 10.1 5.4 0.29 9.7 3.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Med13_C PF06333.7 EAQ88158.1 - 0.69 8.3 8.1 0.88 8.0 5.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF2407_C PF13373.1 EAQ88158.1 - 0.82 9.5 3.9 1.9 8.4 2.7 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain PIRT PF15099.1 EAQ88158.1 - 2.5 7.3 5.1 1 8.6 1.5 1.8 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Glyco_transf_90 PF05686.7 EAQ88159.1 - 5.7e-13 48.3 0.3 1.2e-05 24.2 0.0 4.0 3 2 0 3 3 3 3 Glycosyl transferase family 90 XPG_I_2 PF12813.2 EAQ88160.1 - 1.2e-71 241.0 0.0 1.7e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EAQ88160.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Metallophos PF00149.23 EAQ88162.1 - 7.1e-08 32.0 3.8 3.3e-07 29.9 2.6 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAQ88162.1 - 2.4e-06 27.4 0.0 4.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pribosyltran_N PF13793.1 EAQ88163.1 - 1e-41 141.2 0.0 2.5e-40 136.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EAQ88163.1 - 5.7e-34 117.4 1.7 3.2e-29 102.0 0.1 3.0 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EAQ88163.1 - 9.4e-07 28.6 0.2 0.00039 20.1 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain PAP_assoc PF03828.14 EAQ88164.1 - 8.3e-18 64.0 0.1 6.2e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EAQ88164.1 - 0.0017 18.6 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.7 EAQ88165.1 - 4.8 5.4 52.7 1.5e+02 0.4 35.2 2.6 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 EAQ88166.1 - 1.9e-17 63.8 0.2 1.9e-17 63.8 0.1 1.9 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Zn_clus PF00172.13 EAQ88169.1 - 8.8e-07 28.7 10.3 1.5e-06 28.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKI PF01202.17 EAQ88170.1 - 2.4e-20 72.9 0.0 3.7e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.10 EAQ88170.1 - 9.6e-13 48.2 0.0 5.1e-08 32.8 0.0 2.6 3 0 0 3 3 3 2 Type I 3-dehydroquinase PAP_central PF04928.12 EAQ88171.1 - 8.6e-19 67.3 0.0 3.9e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 Poly(A) polymerase central domain 2_5_RNA_ligase2 PF13563.1 EAQ88171.1 - 1.4e-14 54.1 0.7 2.2e-06 27.4 0.5 2.5 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Exo_endo_phos PF03372.18 EAQ88171.1 - 1.4e-05 25.1 0.0 0.00018 21.5 0.0 2.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family ResIII PF04851.10 EAQ88172.1 - 7.1e-23 81.3 0.0 1.5e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAQ88172.1 - 7.6e-15 54.5 0.0 1.9e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ88172.1 - 1.2e-13 50.9 0.0 3.6e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EAQ88172.1 - 0.0016 17.4 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF3072 PF11272.3 EAQ88172.1 - 0.035 13.7 0.1 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) AAA_22 PF13401.1 EAQ88172.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.22 EAQ88175.1 - 1.4e-40 139.2 0.0 2.1e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_23 PF13489.1 EAQ88176.1 - 0.0001 22.0 0.0 0.00071 19.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88176.1 - 0.0063 16.1 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ88176.1 - 0.018 15.4 0.0 0.88 10.1 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88176.1 - 0.077 13.5 0.0 1.2 9.6 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain YqeY PF09424.5 EAQ88177.1 - 2.1e-18 66.5 4.9 2.5e-18 66.2 3.4 1.1 1 0 0 1 1 1 1 Yqey-like protein SNF2_N PF00176.18 EAQ88178.1 - 1.5e-69 234.0 0.1 2.1e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ88178.1 - 8.2e-10 38.4 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EAQ88178.1 - 9.3e-08 31.9 0.0 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 EAQ88178.1 - 3.5e-05 23.3 0.0 7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EAQ88178.1 - 0.0017 18.0 3.6 0.003 17.2 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAQ88178.1 - 0.24 11.0 3.2 0.55 9.9 2.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.23 EAQ88179.1 - 1.1e-17 63.5 0.0 3.1e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EAQ88179.1 - 6.4e-17 61.8 10.8 6.4e-17 61.8 7.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Pkinase PF00069.20 EAQ88180.1 - 1.3e-12 47.4 0.0 1.6e-11 43.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88180.1 - 4e-12 45.7 0.0 4.5e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.8 EAQ88181.1 - 1e-64 217.6 0.0 2.1e-64 216.6 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EAQ88181.1 - 1.2e-37 129.5 0.0 2.9e-37 128.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EAQ88181.1 - 3.7e-10 40.1 0.6 8.9e-06 25.9 0.0 3.2 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EAQ88181.1 - 1e-08 34.7 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.6 EAQ88181.1 - 2.8e-05 22.9 0.0 6.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_5 PF07728.9 EAQ88181.1 - 5e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAQ88181.1 - 0.00013 21.1 0.0 0.0011 18.0 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAQ88181.1 - 0.00025 21.8 0.0 0.0015 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ88181.1 - 0.0029 17.6 3.6 0.015 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAQ88181.1 - 0.0062 16.6 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ88181.1 - 0.0083 16.4 0.1 0.037 14.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain SKI PF01202.17 EAQ88181.1 - 0.018 14.8 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 EAQ88181.1 - 0.034 13.8 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EAQ88181.1 - 0.037 13.4 0.0 0.096 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAQ88181.1 - 0.038 13.1 0.0 0.09 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EAQ88181.1 - 0.039 13.3 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EAQ88181.1 - 0.041 14.0 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATP-synt_ab PF00006.20 EAQ88181.1 - 0.061 12.8 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 EAQ88181.1 - 0.19 12.0 1.3 0.72 10.1 0.0 2.5 2 1 0 2 2 2 0 ABC transporter eIF3_subunit PF08597.5 EAQ88182.1 - 2.5 7.5 13.0 0.97 8.9 0.2 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF605 PF04652.11 EAQ88182.1 - 2.6 7.3 15.5 3.4 6.9 10.7 1.0 1 0 0 1 1 1 0 Vta1 like Med21 PF11221.3 EAQ88183.1 - 6.9e-30 103.9 1.5 1.6e-29 102.7 1.0 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Lipase_chap PF03280.9 EAQ88183.1 - 0.035 13.6 0.9 0.046 13.2 0.6 1.1 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Med9 PF07544.8 EAQ88183.1 - 0.073 12.8 0.4 0.15 11.7 0.2 1.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HAD_2 PF13419.1 EAQ88184.1 - 2.4e-33 115.8 0.4 3e-33 115.4 0.3 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ88184.1 - 2.5e-08 34.6 0.0 5.5e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ88184.1 - 5e-07 29.3 0.0 7.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EAQ88184.1 - 9.2e-06 25.3 0.1 7.6e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Acid Phosphatase 5_nucleotid PF05761.9 EAQ88184.1 - 0.063 11.7 0.0 0.069 11.6 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase family Rrn6 PF10214.4 EAQ88185.1 - 0.13 10.3 5.0 0.24 9.4 3.4 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor KH_1 PF00013.24 EAQ88186.1 - 1.2e-26 92.0 0.8 1.6e-07 30.8 0.1 6.4 6 0 0 6 6 6 6 KH domain KH_3 PF13014.1 EAQ88186.1 - 1.8e-23 81.7 3.1 1.3e-05 24.6 0.0 5.8 6 0 0 6 6 6 5 KH domain Spc97_Spc98 PF04130.8 EAQ88187.1 - 9.8e-132 440.0 1.5 9.8e-132 440.0 1.1 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Dala_Dala_lig_N PF01820.16 EAQ88187.1 - 0.097 12.9 0.3 0.31 11.3 0.2 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Proteasome PF00227.21 EAQ88188.1 - 1.2e-56 191.0 0.2 1.5e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAQ88188.1 - 6.7e-14 50.8 0.2 2.2e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EAQ88188.1 - 0.13 11.8 0.1 3 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 EAQ88189.1 - 5e-13 48.4 2.1 1.7e-12 46.6 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EAQ88189.1 - 2.5e-06 26.5 0.1 6.3e-06 25.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 EAQ88191.1 - 3e-56 190.4 0.0 7.2e-55 185.9 0.0 2.5 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EAQ88191.1 - 1.6e-07 31.7 0.0 7.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88191.1 - 0.00071 19.1 0.0 0.025 14.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAQ88191.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.7 3 1 0 3 3 3 0 Methyltransferase domain Zip PF02535.17 EAQ88191.1 - 0.89 8.5 6.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Asp_protease PF09668.5 EAQ88192.1 - 4e-59 197.5 0.2 5.7e-59 197.1 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EAQ88192.1 - 5.2e-12 46.0 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EAQ88192.1 - 9.5e-09 34.5 0.1 2.7e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family gag-asp_proteas PF13975.1 EAQ88192.1 - 9.9e-08 31.7 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 EAQ88192.1 - 5.3e-07 29.2 0.0 1.4e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EAQ88192.1 - 2.5e-06 27.4 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EAQ88192.1 - 1e-05 25.3 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EAQ88192.1 - 5.6e-05 22.5 0.1 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain YukD PF08817.5 EAQ88192.1 - 0.0021 18.5 0.0 0.0064 17.0 0.0 1.9 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.3 EAQ88192.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAQ88192.1 - 0.036 14.3 0.1 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.3 EAQ88192.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Acetyltransf_1 PF00583.19 EAQ88193.1 - 2.5e-06 27.4 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pribosyltran PF00156.22 EAQ88194.1 - 2.1e-16 59.7 0.5 3.8e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1 PF06858.9 EAQ88195.1 - 3.6e-28 97.2 0.3 7.3e-28 96.2 0.2 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EAQ88195.1 - 4.6e-28 96.6 0.7 9.5e-28 95.6 0.5 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EAQ88195.1 - 1.9e-10 40.6 0.0 4.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ88195.1 - 5.2e-06 25.8 0.0 9.5e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EAQ88195.1 - 0.00043 20.7 0.0 0.0016 18.9 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EAQ88195.1 - 0.046 13.7 0.1 0.74 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain GDI PF00996.13 EAQ88196.1 - 2.3e-178 593.0 0.0 2.9e-178 592.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor zf-UDP PF14569.1 EAQ88196.1 - 0.093 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger NAD_binding_8 PF13450.1 EAQ88196.1 - 0.11 12.5 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EAQ88197.1 - 1.3e-23 82.6 1.4 2.3e-23 81.8 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.13 EAQ88199.1 - 6.6e-17 61.2 0.1 1.1e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EAQ88199.1 - 7.2e-07 29.2 9.2 3.6e-05 23.8 1.7 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ88199.1 - 1.3e-05 25.1 14.7 0.0014 18.7 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EAQ88199.1 - 0.0035 17.4 5.2 0.0076 16.3 3.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EAQ88199.1 - 0.023 15.0 17.4 0.048 14.0 4.7 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.10 EAQ88199.1 - 9.5 6.0 9.7 1.3 8.8 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger Spc97_Spc98 PF04130.8 EAQ88201.1 - 5.2e-78 262.7 0.0 6.6e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Robl_LC7 PF03259.12 EAQ88201.1 - 0.03 13.9 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Roadblock/LC7 domain Trypan_PARP PF05887.6 EAQ88201.1 - 0.29 10.9 4.1 0.82 9.4 2.9 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DASH_Ask1 PF08655.5 EAQ88202.1 - 3.7e-24 84.3 0.0 6.4e-24 83.5 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Eaf7 PF07904.8 EAQ88202.1 - 2.1e-17 62.8 1.8 2.1e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 GRP PF07172.6 EAQ88202.1 - 0.33 11.4 5.8 1.2 9.6 4.0 1.9 1 0 0 1 1 1 0 Glycine rich protein family Nucleoplasmin PF03066.10 EAQ88202.1 - 7.1 6.1 12.3 1.2 8.6 4.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 EAQ88202.1 - 9.7 6.4 12.3 15 5.8 4.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF4553 PF15090.1 EAQ88203.1 - 0.11 11.4 5.7 0.11 11.5 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Ribonuc_red_lgN PF00317.16 EAQ88204.1 - 0.17 11.6 1.7 5.2 6.9 0.0 2.9 2 1 1 3 3 3 0 Ribonucleotide reductase, all-alpha domain AAA_33 PF13671.1 EAQ88205.1 - 5.4e-16 58.7 0.0 1.3e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAQ88205.1 - 2.7e-08 33.1 0.0 5.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EAQ88205.1 - 1e-07 32.2 0.0 7.4e-07 29.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EAQ88205.1 - 1.7e-06 28.8 0.2 8.2e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EAQ88205.1 - 3.3e-05 23.2 0.0 3.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CoaE PF01121.15 EAQ88205.1 - 3.6e-05 23.2 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.1 EAQ88205.1 - 0.0024 17.8 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EAQ88205.1 - 0.0041 16.6 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EAQ88205.1 - 0.0067 15.9 0.1 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAQ88205.1 - 0.0077 16.2 0.0 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EAQ88205.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 EAQ88205.1 - 0.015 14.1 0.0 0.033 12.9 0.0 1.5 2 0 0 2 2 2 0 ArgK protein MMR_HSR1 PF01926.18 EAQ88205.1 - 0.021 14.7 0.0 0.099 12.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin2 PF13189.1 EAQ88205.1 - 0.027 14.3 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_22 PF13401.1 EAQ88205.1 - 0.03 14.4 0.0 0.081 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EAQ88205.1 - 0.037 13.1 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAQ88205.1 - 0.039 14.1 0.0 0.064 13.4 0.0 1.5 1 1 0 1 1 1 0 RNA helicase 6PF2K PF01591.13 EAQ88205.1 - 0.058 12.4 0.0 8.8 5.3 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase NB-ARC PF00931.17 EAQ88205.1 - 0.084 11.7 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EAQ88205.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1487 PF07368.6 EAQ88205.1 - 0.099 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Viral_helicase1 PF01443.13 EAQ88205.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EAQ88205.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EAQ88205.1 - 0.15 12.2 0.0 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAQ88205.1 - 0.15 11.4 0.4 1 8.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain p450 PF00067.17 EAQ88206.1 - 5.2e-54 183.5 0.0 7e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Yip1 PF04893.12 EAQ88207.1 - 3.8e-13 49.2 16.1 7e-13 48.4 11.1 1.5 1 1 0 1 1 1 1 Yip1 domain Ribosomal_L40e PF01020.12 EAQ88208.1 - 1.1e-30 104.9 9.9 1.3e-30 104.7 6.9 1.1 1 0 0 1 1 1 1 Ribosomal L40e family KOW PF00467.24 EAQ88210.1 - 3.1e-05 23.5 0.8 5.7e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EAQ88210.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 EAQ88211.1 - 7.9e-101 338.0 0.1 3e-73 247.1 0.0 2.0 1 1 1 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 EAQ88211.1 - 2.3e-05 22.7 0.2 9.1e-05 20.7 0.0 1.8 1 1 1 2 2 2 1 Exocyst complex component Sec3 Mer2 PF09074.5 EAQ88211.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Mer2 DUF1664 PF07889.7 EAQ88211.1 - 0.018 14.8 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EAQ88211.1 - 0.023 14.5 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RabGAP-TBC PF00566.13 EAQ88212.1 - 1.8e-20 73.3 0.0 2.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 EAQ88213.1 - 1.1e-77 261.3 0.0 3.2e-77 259.8 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 EAQ88214.1 - 1.9e-32 112.2 0.0 1.9e-32 112.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EAQ88214.1 - 1.8e-18 66.4 0.0 5.3e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EAQ88214.1 - 8.2e-10 38.6 6.2 2.8e-07 30.5 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAQ88214.1 - 9.5e-07 28.7 0.1 4.7e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EAQ88214.1 - 0.00026 20.6 0.0 0.00071 19.1 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EAQ88214.1 - 0.001 19.5 1.0 0.0042 17.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EAQ88214.1 - 0.044 13.9 0.1 0.43 10.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EAQ88214.1 - 0.052 12.8 0.1 0.48 9.6 0.1 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Arena_glycoprot PF00798.13 EAQ88214.1 - 0.22 9.8 0.8 0.32 9.3 0.0 1.5 2 0 0 2 2 2 0 Arenavirus glycoprotein HSP70 PF00012.15 EAQ88215.1 - 2.5e-158 527.6 14.2 2.5e-158 527.6 9.9 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ88215.1 - 6.5e-11 41.3 0.0 5.8e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EAQ88215.1 - 0.00055 19.7 2.3 3.9 7.3 0.1 4.0 2 2 0 2 2 2 2 Cell division protein FtsA BcrAD_BadFG PF01869.15 EAQ88215.1 - 0.022 14.0 0.0 0.1 11.8 0.0 2.0 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Trans_reg_C PF00486.23 EAQ88215.1 - 0.072 13.0 0.1 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Chitin_synth_2 PF03142.10 EAQ88216.1 - 3.2e-15 55.5 0.3 5.2e-15 54.8 0.2 1.3 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EAQ88216.1 - 2.4e-12 46.9 0.2 3.7e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAQ88216.1 - 9e-09 35.4 1.7 1.2e-07 31.8 0.4 2.0 1 1 1 2 2 2 2 Glycosyltransferase like family 2 MIF4G PF02854.14 EAQ88218.1 - 1.5e-60 204.2 0.0 5.5e-31 107.6 0.0 3.9 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.9 EAQ88218.1 - 1.2e-47 161.8 6.5 1.2e-47 161.8 4.5 2.2 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Mo-co_dimer PF03404.11 EAQ88219.1 - 1.3e-53 180.1 0.0 2.1e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EAQ88219.1 - 1.4e-51 174.2 0.0 2.1e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EAQ88219.1 - 7.4e-29 99.7 0.0 1.5e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain HTH_29 PF13551.1 EAQ88220.1 - 2.3e-06 27.7 0.6 3.1e-06 27.2 0.4 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EAQ88220.1 - 0.00032 20.6 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EAQ88220.1 - 0.00051 19.5 0.8 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EAQ88220.1 - 0.0039 17.9 1.3 0.0075 17.0 0.7 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EAQ88220.1 - 0.0081 16.1 0.4 0.016 15.2 0.1 1.6 2 0 0 2 2 2 1 Transposase Bunya_NS-S PF01104.12 EAQ88220.1 - 0.32 10.4 2.3 0.58 9.6 1.5 1.5 1 1 0 1 1 1 0 Bunyavirus non-structural protein NS-s ETC_C1_NDUFA5 PF04716.9 EAQ88221.1 - 3.3e-22 77.7 0.0 9.1e-22 76.3 0.0 1.8 1 0 0 1 1 1 1 ETC complex I subunit conserved region PAS_3 PF08447.6 EAQ88223.1 - 1.5e-15 57.0 0.0 9.7e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EAQ88223.1 - 2.8e-10 40.4 0.0 0.00043 20.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EAQ88223.1 - 3.3e-09 36.5 0.0 0.00064 19.4 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EAQ88223.1 - 1.8e-05 24.7 0.0 0.056 13.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EAQ88223.1 - 0.0019 18.1 0.0 0.0078 16.1 0.0 1.8 2 0 0 2 2 2 1 PAS domain DUF3439 PF11921.3 EAQ88224.1 - 0.11 12.2 1.6 0.17 11.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Na_Ca_ex PF01699.19 EAQ88225.1 - 3.6e-26 91.4 15.6 3.1e-15 56.0 2.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.7 EAQ88225.1 - 0.0083 15.1 1.9 0.033 13.1 0.0 2.1 1 1 1 2 2 2 1 7tm Chemosensory receptor DUF4131 PF13567.1 EAQ88225.1 - 0.64 9.3 4.4 36 3.7 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DEAD PF00270.24 EAQ88226.1 - 4.6e-16 58.7 0.0 1.7e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ88226.1 - 3.2e-09 36.5 0.0 9e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EAQ88226.1 - 0.0087 16.6 0.0 0.031 14.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Menin PF05053.8 EAQ88226.1 - 9 4.3 6.5 13 3.8 4.5 1.1 1 0 0 1 1 1 0 Menin Ran_BP1 PF00638.13 EAQ88227.1 - 8.6e-07 29.0 1.1 0.00018 21.5 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain CDK5_activator PF03261.10 EAQ88227.1 - 3.4 6.9 6.0 6.2 6.0 4.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein zf-RING_2 PF13639.1 EAQ88229.1 - 1.6e-14 53.4 16.3 2.1e-14 53.0 3.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EAQ88229.1 - 2.3e-10 39.9 10.4 1.3e-08 34.3 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAQ88229.1 - 2.9e-07 30.4 2.5 2.9e-07 30.4 1.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAQ88229.1 - 5.8e-07 29.0 16.6 8.3e-06 25.3 4.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ88229.1 - 2.9e-06 26.8 11.5 3.6e-05 23.3 2.5 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAQ88229.1 - 1.2e-05 25.1 7.1 1.2e-05 25.1 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EAQ88229.1 - 1.6e-05 24.7 5.3 3.5e-05 23.6 1.9 2.4 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 EAQ88229.1 - 0.015 15.1 2.1 0.015 15.1 1.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.14 EAQ88229.1 - 0.027 14.1 0.4 0.027 14.1 0.3 1.8 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 EAQ88229.1 - 0.041 13.6 10.9 0.73 9.6 3.7 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EAQ88229.1 - 0.26 10.9 13.4 0.52 10.0 4.0 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.1 EAQ88229.1 - 0.76 9.4 12.3 1.9 8.1 2.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EAQ88229.1 - 1.8 8.3 4.7 0.8 9.5 0.8 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Fis1_TPR_C PF14853.1 EAQ88230.1 - 1.2e-24 85.9 0.7 1.6e-24 85.5 0.5 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EAQ88230.1 - 7.7e-11 41.1 0.0 1.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EAQ88230.1 - 0.0022 17.7 0.3 0.0041 16.9 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ88230.1 - 0.086 13.5 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EAQ88231.1 - 4.5e-40 136.0 0.0 1e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 EAQ88231.1 - 0.044 12.9 2.2 0.062 12.4 1.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1633 PF07794.6 EAQ88231.1 - 0.045 11.7 0.1 0.066 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Streptin-Immun PF11083.3 EAQ88231.1 - 0.11 12.5 0.3 0.86 9.6 0.0 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Troponin PF00992.15 EAQ88231.1 - 0.22 11.5 3.0 0.35 10.9 2.1 1.2 1 0 0 1 1 1 0 Troponin ATG16 PF08614.6 EAQ88231.1 - 0.24 11.1 7.8 20 4.9 5.8 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EAQ88231.1 - 0.27 10.2 3.2 0.38 9.7 2.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 EAQ88231.1 - 1.1 9.1 4.8 1.8 8.3 0.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 EAQ88231.1 - 3.2 5.4 4.5 0.39 8.5 0.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 EAQ88231.1 - 6.3 6.6 9.3 2.9 7.7 4.0 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TatD_DNase PF01026.16 EAQ88232.1 - 7.8e-30 103.9 0.0 2.4e-29 102.3 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 EAQ88233.1 - 2e-12 46.5 0.2 7.1e-08 31.6 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Nol1_Nop2_Fmu PF01189.12 EAQ88234.1 - 5.2e-40 137.6 0.0 4.5e-19 68.9 0.0 4.2 4 1 1 5 5 5 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EAQ88234.1 - 0.0021 18.1 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAQ88234.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF3085 PF11284.3 EAQ88234.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) FoP_duplication PF13865.1 EAQ88234.1 - 2.3 8.7 6.2 7 7.1 4.3 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 GTP1_OBG PF01018.17 EAQ88235.1 - 6.6e-36 123.3 5.4 7e-28 97.2 2.3 2.5 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 EAQ88235.1 - 6.9e-21 74.3 0.0 1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ88235.1 - 1.9e-07 30.5 0.2 6e-07 28.8 0.1 1.9 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.22 EAQ88235.1 - 0.04 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EAQ88235.1 - 0.059 12.7 0.0 8.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EAQ88235.1 - 0.083 12.1 0.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family ArgK PF03308.11 EAQ88235.1 - 0.085 11.6 0.1 0.69 8.6 0.0 2.3 3 0 0 3 3 3 0 ArgK protein APH PF01636.18 EAQ88237.1 - 3e-12 46.7 0.3 7.1e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ88237.1 - 2.8e-07 30.3 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EAQ88237.1 - 0.03 12.9 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 EAQ88237.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Reo_sigmaC PF04582.7 EAQ88238.1 - 0.047 12.8 2.6 0.15 11.2 1.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Occludin_ELL PF07303.8 EAQ88238.1 - 0.24 12.1 26.1 0.16 12.7 3.9 4.6 2 1 2 4 4 4 0 Occludin homology domain Hemagglutinin PF00509.13 EAQ88238.1 - 0.54 8.3 6.1 0.16 10.0 0.5 2.3 2 0 0 2 2 2 0 Haemagglutinin CorA PF01544.13 EAQ88238.1 - 3.2 6.6 8.4 0.39 9.6 2.2 2.1 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein RNA_pol_Rpb5_C PF01191.14 EAQ88239.1 - 1.4e-35 120.6 0.3 2.2e-35 120.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EAQ88239.1 - 5e-16 58.8 0.0 8.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain AAA_3 PF07726.6 EAQ88239.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mrr_cat PF04471.7 EAQ88239.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease Zip PF02535.17 EAQ88243.1 - 2.8e-53 180.9 6.0 6.7e-52 176.4 4.1 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Bul1_C PF04426.7 EAQ88244.1 - 1.6e-08 34.1 0.0 2.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.7 EAQ88244.1 - 3e-06 26.0 3.1 1.6e-05 23.7 0.0 3.1 3 1 1 4 4 4 1 Bul1 N terminus Arrestin_N PF00339.24 EAQ88244.1 - 0.057 13.2 0.0 0.3 10.9 0.0 2.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Metallophos_2 PF12850.2 EAQ88246.1 - 2.1e-05 24.3 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ88246.1 - 0.00093 18.6 9.0 0.0052 16.1 6.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pex2_Pex12 PF04757.9 EAQ88247.1 - 2.2e-55 187.5 2.7 3.8e-55 186.8 1.9 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EAQ88247.1 - 0.00052 19.9 2.6 0.00089 19.2 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ88247.1 - 0.02 14.7 2.5 0.032 14.0 1.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EAQ88247.1 - 0.031 14.1 1.4 0.053 13.3 1.0 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING F-box PF00646.28 EAQ88248.1 - 1.7e-08 33.9 0.1 1.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAQ88248.1 - 1.3e-07 31.2 1.3 1.3e-07 31.2 0.1 1.7 2 0 0 2 2 2 1 F-box-like Fungal_trans PF04082.13 EAQ88249.1 - 7.4e-62 208.5 0.1 1e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EAQ88249.1 - 0.057 13.7 0.1 0.17 12.2 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type SAP30_Sin3_bdg PF13867.1 EAQ88251.1 - 1.4e-12 47.2 0.9 3.4e-11 42.8 0.1 2.2 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 CTDII PF01556.13 EAQ88252.1 - 1.7e-28 98.3 0.9 1.4e-21 76.1 0.0 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EAQ88252.1 - 1.3e-23 82.5 1.2 2.4e-23 81.6 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EAQ88252.1 - 1.4e-10 41.0 20.4 2.7e-10 40.1 14.1 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF2076 PF09849.4 EAQ88252.1 - 0.018 15.1 1.4 0.041 13.9 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4414 PF14377.1 EAQ88252.1 - 0.26 11.1 2.6 0.48 10.3 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) HypA PF01155.14 EAQ88252.1 - 2.9 7.6 9.4 7.6 6.2 0.7 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 EAQ88253.1 - 3.7e-39 134.4 43.8 3.8e-38 131.0 29.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88253.1 - 1.1e-10 40.7 38.3 2.3e-08 33.0 10.4 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EAQ88253.1 - 3.9e-09 35.2 18.3 9.3e-09 34.0 12.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NDUF_B12 PF08122.7 EAQ88253.1 - 0.0098 15.6 0.3 7.5 6.3 0.0 2.8 2 0 0 2 2 2 2 NADH-ubiquinone oxidoreductase B12 subunit family Fungal_trans PF04082.13 EAQ88254.1 - 2.6e-22 78.9 0.0 4.3e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88254.1 - 1.2e-08 34.6 11.3 2.2e-08 33.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.14 EAQ88255.1 - 9.2e-16 58.0 17.9 9.2e-16 58.0 12.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EAQ88255.1 - 4.3e-07 29.7 0.1 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ctr PF04145.10 EAQ88256.1 - 1.1e-11 45.0 0.1 1.8e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Ctr copper transporter family ABC2_membrane PF01061.19 EAQ88256.1 - 0.026 13.6 2.1 0.034 13.3 1.4 1.2 1 0 0 1 1 1 0 ABC-2 type transporter Ferric_reduct PF01794.14 EAQ88257.1 - 1.3e-18 67.2 11.2 1.3e-18 67.2 7.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EAQ88257.1 - 0.0014 18.4 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EAQ88257.1 - 0.0021 17.9 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EAQ88257.1 - 0.0039 17.7 0.1 1.9 9.0 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain zf-RING_2 PF13639.1 EAQ88258.1 - 1.1e-13 50.7 3.0 1.5e-13 50.2 2.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAQ88258.1 - 2.4e-09 36.6 0.8 3.3e-09 36.2 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAQ88258.1 - 1.6e-08 34.5 1.2 2.3e-08 34.0 0.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAQ88258.1 - 5.7e-08 32.6 2.0 7.9e-08 32.1 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ88258.1 - 1.9e-06 27.4 0.8 2.8e-06 26.9 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ88258.1 - 3.3e-06 26.7 1.2 4.6e-06 26.2 0.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAQ88258.1 - 4.3e-05 23.2 0.5 6.3e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EAQ88258.1 - 0.00024 21.0 0.8 0.00036 20.5 0.5 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EAQ88258.1 - 0.0051 16.5 0.5 0.0089 15.7 0.1 1.5 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 EAQ88258.1 - 0.011 15.7 3.2 0.089 12.7 2.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EAQ88258.1 - 0.021 14.6 1.7 0.036 13.9 1.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EAQ88258.1 - 0.024 14.1 2.6 0.043 13.3 1.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 EAQ88258.1 - 0.073 13.0 2.2 0.11 12.4 1.6 1.3 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EAQ88258.1 - 0.18 11.3 0.8 0.27 10.8 0.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 EAQ88259.1 - 3e-07 30.0 8.3 6.1e-07 29.0 5.8 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EAQ88259.1 - 4.6e-05 23.7 0.4 0.00056 20.2 0.0 2.9 3 0 0 3 3 3 1 SET domain E1_DerP2_DerF2 PF02221.10 EAQ88260.1 - 2.3e-09 37.5 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EAQ88260.1 - 0.029 14.3 0.0 0.032 14.2 0.0 1.3 1 1 0 1 1 1 0 ML-like domain ATP-synt_F PF01990.12 EAQ88261.1 - 4e-24 84.8 0.1 5.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MOSC_N PF03476.11 EAQ88261.1 - 0.0017 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2418 PF10332.4 EAQ88262.1 - 1.8e-35 121.1 0.9 2.9e-35 120.5 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF4113 PF13438.1 EAQ88263.1 - 0.43 10.2 2.3 0.71 9.5 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) Aconitase PF00330.15 EAQ88264.1 - 2.5e-180 599.9 0.0 3.2e-180 599.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAQ88264.1 - 5.4e-40 136.5 0.0 1.1e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Metallophos_3 PF14582.1 EAQ88265.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Methyltransf_23 PF13489.1 EAQ88266.1 - 9e-18 64.5 0.0 1.4e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ88266.1 - 1.4e-08 35.0 0.0 2.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88266.1 - 1.5e-08 35.2 0.1 2.3e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ88266.1 - 4.4e-07 30.2 0.0 2.8e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88266.1 - 8.6e-07 28.6 0.0 1.3e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ88266.1 - 0.00014 22.1 0.0 0.00037 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAQ88266.1 - 0.00093 19.2 0.1 0.0027 17.7 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EAQ88266.1 - 0.025 13.6 0.0 0.074 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 EAQ88266.1 - 0.052 12.6 0.0 0.5 9.4 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EAQ88266.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EAQ88266.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase CDC45 PF02724.9 EAQ88268.1 - 1.9e-59 201.2 0.1 5.6e-52 176.6 0.0 4.2 2 1 2 4 4 4 3 CDC45-like protein Ribosomal_60s PF00428.14 EAQ88268.1 - 1.9 8.9 9.1 6 7.3 6.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein EF-hand_1 PF00036.27 EAQ88269.1 - 2.7e-25 85.7 10.0 3.3e-08 32.2 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EAQ88269.1 - 1.2e-23 80.8 2.4 1.5e-06 27.6 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EAQ88269.1 - 2.5e-22 78.8 2.8 6.5e-14 51.8 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAQ88269.1 - 2e-18 64.8 12.0 1.3e-05 24.3 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EAQ88269.1 - 1.2e-15 56.8 10.0 2e-06 27.2 0.4 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EAQ88269.1 - 5e-09 35.8 5.4 0.0023 17.6 0.1 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EAQ88269.1 - 0.0002 21.2 0.6 0.0044 16.8 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EAQ88269.1 - 0.00024 21.0 1.7 0.21 11.6 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EAQ88269.1 - 0.0081 15.8 3.4 0.65 9.7 0.0 3.6 5 0 0 5 5 5 1 EF hand EF-hand_2 PF09068.6 EAQ88269.1 - 0.0082 16.2 0.1 1 9.4 0.0 2.9 3 1 0 3 3 3 1 EF hand AMP-binding PF00501.23 EAQ88270.1 - 6.5e-78 261.9 0.1 9.9e-78 261.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ88270.1 - 0.011 16.7 0.3 0.037 14.9 0.2 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CdhD PF03599.11 EAQ88270.1 - 0.059 11.8 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Transglut_core PF01841.14 EAQ88271.1 - 2.6e-09 37.2 0.0 5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EAQ88271.1 - 0.091 12.0 0.0 2.2 7.5 0.0 2.5 2 1 0 2 2 2 0 Transglutaminase-like domain F-box-like PF12937.2 EAQ88272.1 - 6.1e-06 25.8 0.2 1.3e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ88272.1 - 3.4e-05 23.3 0.2 8.4e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain Fungal_trans_2 PF11951.3 EAQ88273.1 - 0.012 14.1 0.1 0.032 12.8 0.0 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain Glycos_transf_4 PF00953.16 EAQ88274.1 - 2.2e-32 112.0 10.4 2.2e-32 112.0 7.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 HTH_psq PF05225.11 EAQ88274.1 - 2.2e-09 36.7 0.2 4.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain BNR_2 PF13088.1 EAQ88275.1 - 1.9e-07 30.6 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EAQ88275.1 - 0.0066 16.0 8.2 0.16 11.9 0.3 3.3 3 0 0 3 3 3 2 BNR/Asp-box repeat WD40 PF00400.27 EAQ88276.1 - 7.9e-09 35.0 0.3 8.7e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat MFS_1 PF07690.11 EAQ88277.1 - 1.4e-18 66.7 14.1 1.9e-18 66.3 9.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ88277.1 - 0.0088 15.8 2.6 0.014 15.1 0.2 2.4 2 0 0 2 2 2 1 MFS_1 like family Nop14 PF04147.7 EAQ88277.1 - 0.047 11.6 7.0 0.065 11.1 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EAQ88277.1 - 4.6 6.3 6.9 0.44 9.6 1.7 1.4 2 0 0 2 2 2 0 Myc amino-terminal region CDC45 PF02724.9 EAQ88277.1 - 5.6 4.8 10.9 8 4.3 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ThiF PF00899.16 EAQ88281.1 - 4.3e-52 175.5 0.1 1.1e-32 112.7 0.0 2.8 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EAQ88281.1 - 3.2e-39 133.9 0.0 4.3e-37 127.0 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EAQ88281.1 - 4.1e-39 131.9 4.4 1.9e-27 94.6 0.3 3.1 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAQ88281.1 - 5.4e-23 80.1 1.0 1.3e-19 69.2 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 EAQ88282.1 - 3.3e-18 65.4 0.0 6.2e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ88282.1 - 0.053 13.7 0.0 0.88 9.8 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chitin_synth_2 PF03142.10 EAQ88283.1 - 2.3e-112 376.0 8.1 1.5e-67 228.2 0.4 2.3 2 1 1 3 3 3 2 Chitin synthase DEK_C PF08766.6 EAQ88283.1 - 1.4e-15 56.8 0.1 5.1e-15 54.9 0.1 1.8 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EAQ88283.1 - 5e-08 32.8 4.8 7.4e-08 32.3 3.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAQ88283.1 - 9.3e-06 25.5 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1353 PF07087.6 EAQ88283.1 - 0.022 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Chitin_synth_2 PF03142.10 EAQ88284.1 - 2.3e-228 758.8 0.0 3e-228 758.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EAQ88284.1 - 5.8e-54 183.2 0.0 1e-45 156.0 0.0 2.7 2 1 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 EAQ88284.1 - 4.4e-19 68.0 0.0 3.8e-11 42.6 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EAQ88284.1 - 3.2e-18 66.1 3.3 3.2e-18 66.1 2.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAQ88284.1 - 3.6e-15 56.4 0.0 1.9e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAQ88284.1 - 4.1e-06 26.1 0.0 8.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EAQ88284.1 - 0.0012 18.5 0.0 0.089 12.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF663 PF04950.7 EAQ88285.1 - 1.4e-89 300.0 0.0 2.4e-89 299.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EAQ88285.1 - 1.8e-26 91.4 0.0 1e-25 89.0 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EAQ88285.1 - 0.00086 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EAQ88285.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation BCDHK_Adom3 PF10436.4 EAQ88286.1 - 1.7e-41 141.4 0.0 3.4e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EAQ88286.1 - 1.5e-15 56.9 0.0 1.1e-13 50.9 0.0 2.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 EAQ88286.1 - 7.3e-08 32.8 0.1 2.5e-07 31.1 0.1 2.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1681 PF07933.9 EAQ88288.1 - 1.2e-52 177.7 0.0 1.8e-52 177.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) Mito_fiss_reg PF05308.6 EAQ88288.1 - 0.63 9.3 3.5 9.8 5.4 1.7 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator IF-2B PF01008.12 EAQ88289.1 - 2.6e-16 59.4 3.6 4.8e-14 52.0 0.5 2.2 1 1 1 2 2 2 2 Initiation factor 2 subunit family ATP-grasp_2 PF08442.5 EAQ88289.1 - 0.035 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain 4_1_CTD PF05902.8 EAQ88289.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Methyltransf_25 PF13649.1 EAQ88291.1 - 5.3e-05 23.5 0.0 0.00023 21.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ88291.1 - 0.065 13.7 0.0 0.15 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain FGE-sulfatase PF03781.11 EAQ88292.1 - 7.7e-18 64.7 1.6 2.4e-12 46.7 0.2 2.4 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EAQ88292.1 - 6e-08 33.0 0.2 1.4e-07 31.8 0.2 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_33 PF10017.4 EAQ88292.1 - 9.9e-06 25.4 0.2 2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent GFA PF04828.9 EAQ88293.1 - 5.3e-06 26.2 0.2 5.3e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PfkB PF00294.19 EAQ88294.1 - 4.7e-50 170.4 0.7 5.4e-50 170.2 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NOA36 PF06524.7 EAQ88295.1 - 0.0066 15.7 2.7 0.011 15.0 1.9 1.2 1 0 0 1 1 1 1 NOA36 protein zf-C2H2_4 PF13894.1 EAQ88295.1 - 0.066 13.5 0.6 0.066 13.5 0.4 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ88295.1 - 1 9.7 10.3 0.44 10.9 0.6 4.1 4 0 0 4 4 4 0 Zinc-finger double domain eIF3_subunit PF08597.5 EAQ88296.1 - 6.6e-40 137.2 7.4 8.8e-40 136.8 5.1 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit MDM31_MDM32 PF08118.6 EAQ88297.1 - 1.6e-186 620.6 1.6 4e-137 457.7 0.4 2.0 2 0 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins Ribosomal_60s PF00428.14 EAQ88297.1 - 0.0013 19.0 3.6 0.24 11.7 0.1 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF3825 PF12873.2 EAQ88297.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Rad60-SLD PF11976.3 EAQ88299.1 - 1.1e-12 47.4 0.1 2.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BCS1_N PF08740.6 EAQ88299.1 - 0.042 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 BCS1 N terminal DUF605 PF04652.11 EAQ88299.1 - 9 5.5 27.0 14 4.9 18.7 1.2 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 EAQ88299.1 - 9.8 5.2 12.9 16 4.5 8.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) adh_short PF00106.20 EAQ88300.1 - 1.5e-20 73.7 1.9 2.3e-20 73.1 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ88300.1 - 5.1e-16 59.1 0.1 9.1e-16 58.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ88300.1 - 2.3e-07 30.6 2.7 1.6e-06 27.8 1.9 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ88300.1 - 0.00011 21.7 0.5 0.00051 19.5 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EAQ88300.1 - 0.015 15.6 0.4 0.027 14.8 0.3 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EAQ88300.1 - 0.02 14.8 1.6 0.18 11.7 0.5 2.2 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EAQ88300.1 - 0.062 12.1 0.1 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EAQ88300.1 - 0.11 12.6 0.3 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EAQ88301.1 - 7.1e-33 113.7 24.6 7.1e-33 113.7 17.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88301.1 - 0.00025 19.7 5.3 0.00025 19.7 3.7 4.7 4 1 1 5 5 5 3 Sugar (and other) transporter CFEM PF05730.6 EAQ88302.1 - 2.7e-12 46.3 9.0 2.7e-12 46.3 6.2 1.5 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.6 EAQ88302.1 - 0.71 7.6 6.0 0.71 7.6 4.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.4 EAQ88303.1 - 0.15 10.2 13.8 0.2 9.8 9.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EAQ88303.1 - 3.7 6.8 21.2 6 6.1 14.7 1.3 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EAQ88305.1 - 3.1e-32 111.7 2.9 3.8e-32 111.4 1.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ88305.1 - 3.2e-23 82.7 0.6 2e-22 80.1 0.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ88305.1 - 4.8e-15 55.6 1.2 7.6e-15 55.0 0.8 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EAQ88305.1 - 0.00073 19.2 0.4 0.0011 18.6 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EAQ88305.1 - 0.0018 18.1 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MobC PF05713.6 EAQ88305.1 - 0.051 13.5 0.2 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) Glycos_transf_2 PF00535.21 EAQ88306.1 - 4.3e-27 94.8 0.0 5.2e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EAQ88306.1 - 9.1e-12 45.2 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EAQ88306.1 - 3.8e-08 32.7 0.0 4.6e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EAQ88306.1 - 0.045 14.0 0.0 0.16 12.3 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAQ88306.1 - 0.052 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 E1-E2_ATPase PF00122.15 EAQ88307.1 - 1.7e-63 213.7 1.9 3.1e-63 212.8 1.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAQ88307.1 - 2.3e-33 115.2 1.3 2.3e-33 115.2 0.9 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAQ88307.1 - 3.2e-27 96.3 0.5 1.3e-22 81.2 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ88307.1 - 1.9e-18 66.1 0.0 4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAQ88307.1 - 1.8e-13 49.7 0.0 5.2e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAQ88307.1 - 1.1e-11 45.2 0.0 2.6e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ88307.1 - 1.6e-06 27.9 0.2 9.1e-06 25.4 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_85 PF03644.8 EAQ88309.1 - 0.24 10.4 1.1 0.37 9.8 0.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF221 PF02714.10 EAQ88310.1 - 1.7e-99 332.7 16.6 1.7e-99 332.7 11.5 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAQ88310.1 - 1.2e-36 125.6 4.9 1.2e-36 125.6 3.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EAQ88310.1 - 2e-14 53.8 0.2 4.1e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TMA7 PF09072.5 EAQ88311.1 - 1.7e-26 92.4 19.4 1.9e-26 92.2 13.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 HSP70 PF00012.15 EAQ88311.1 - 0.038 11.8 0.4 0.043 11.7 0.2 1.0 1 0 0 1 1 1 0 Hsp70 protein Pkinase PF00069.20 EAQ88312.1 - 3.5e-53 180.4 0.0 4.7e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88312.1 - 1.3e-23 83.4 0.0 2.8e-23 82.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAQ88312.1 - 0.051 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EAQ88312.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EAQ88312.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EAQ88313.1 - 1.4e-57 194.7 0.0 1.9e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88313.1 - 3e-30 105.1 0.0 3.7e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ88313.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ88313.1 - 0.0034 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ88313.1 - 0.047 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAQ88313.1 - 0.23 10.7 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ATP-synt_J PF04911.7 EAQ88314.1 - 0.011 15.1 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 ATP synthase j chain CCDC71L PF15374.1 EAQ88315.1 - 0.13 11.5 2.5 0.14 11.4 1.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Opi1 PF08618.5 EAQ88315.1 - 0.19 10.5 3.3 0.21 10.4 2.3 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 AAA_19 PF13245.1 EAQ88316.1 - 0.0024 17.5 1.5 1.1 9.0 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain DUF3499 PF12005.3 EAQ88316.1 - 0.11 12.6 0.0 4.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) BLOC1_2 PF10046.4 EAQ88316.1 - 0.3 11.2 4.4 3 8.0 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40 PF00400.27 EAQ88317.1 - 3.8 7.5 9.7 7.8 6.5 1.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat RVT_1 PF00078.22 EAQ88318.1 - 1.3e-31 109.6 0.0 2.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ88318.1 - 1e-21 76.7 0.0 8.5e-21 73.7 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase NB-ARC PF00931.17 EAQ88318.1 - 6.1e-11 41.7 0.0 1.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Exo_endo_phos PF03372.18 EAQ88318.1 - 1.3e-08 35.1 0.1 2.6e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_22 PF13401.1 EAQ88318.1 - 1.4e-05 25.2 0.4 0.00019 21.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ88318.1 - 0.0037 16.9 0.4 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TPR_12 PF13424.1 EAQ88318.1 - 0.0046 16.8 1.3 0.21 11.5 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ88318.1 - 0.0081 16.0 0.2 0.0081 16.0 0.1 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EAQ88318.1 - 0.012 14.5 0.7 0.035 13.0 0.5 1.7 1 0 0 1 1 1 0 Phosphorylase superfamily WGR PF05406.10 EAQ88318.1 - 0.013 15.4 0.7 0.045 13.7 0.5 1.9 1 0 0 1 1 1 0 WGR domain HEPN PF05168.9 EAQ88318.1 - 0.014 15.2 0.2 0.062 13.2 0.1 2.1 1 0 0 1 1 1 0 HEPN domain SlyX PF04102.7 EAQ88318.1 - 0.022 15.1 4.3 0.42 11.0 3.0 2.9 1 1 1 2 2 2 0 SlyX DUF4618 PF15397.1 EAQ88318.1 - 0.07 12.4 4.5 5.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) CorA PF01544.13 EAQ88318.1 - 0.11 11.4 1.9 0.24 10.4 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Rax2 PF12768.2 EAQ88319.1 - 0.00038 19.7 0.0 0.00058 19.1 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Plasmodium_Vir PF05795.6 EAQ88319.1 - 0.03 13.5 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAD_binding_4 PF01565.18 EAQ88320.1 - 6.9e-15 54.7 0.7 1.5e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ88320.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like TauD PF02668.11 EAQ88322.1 - 1.9e-35 122.8 0.2 2.4e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TRIC PF05197.8 EAQ88324.1 - 0.024 14.0 0.1 0.041 13.2 0.1 1.3 1 0 0 1 1 1 0 TRIC channel Radical_SAM PF04055.16 EAQ88325.1 - 1.6e-10 41.3 0.0 2.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EAQ88325.1 - 2.1e-07 31.1 0.0 3.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EAQ88325.1 - 1.5e-06 28.2 0.0 4e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain ADK PF00406.17 EAQ88326.1 - 1e-08 35.2 0.0 5e-07 29.7 0.0 2.0 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.1 EAQ88326.1 - 8.8e-06 26.5 0.1 1.5e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ88326.1 - 0.019 14.8 0.0 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 EAQ88326.1 - 0.02 15.1 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 EAQ88326.1 - 0.023 14.0 0.0 0.13 11.6 0.0 2.1 1 1 2 3 3 3 0 Thymidylate kinase AAA_18 PF13238.1 EAQ88326.1 - 0.12 12.7 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Dimer_Tnp_hAT PF05699.9 EAQ88327.1 - 5e-15 54.8 0.1 1.2e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MMR_HSR1 PF01926.18 EAQ88328.1 - 2.9e-08 33.6 0.0 5.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAQ88328.1 - 3.8e-05 22.9 0.0 5.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAQ88328.1 - 9.6e-05 21.6 0.1 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EAQ88328.1 - 0.00048 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EAQ88328.1 - 0.00087 19.1 0.3 0.0023 17.7 0.1 1.8 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 EAQ88328.1 - 0.0028 16.5 0.2 0.0048 15.8 0.2 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EAQ88328.1 - 0.0036 17.5 0.3 0.0077 16.5 0.2 1.5 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.4 EAQ88328.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EAQ88328.1 - 0.015 15.4 0.1 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ88328.1 - 0.016 15.5 0.1 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAQ88328.1 - 0.02 13.9 0.1 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EAQ88328.1 - 0.022 15.5 0.2 0.048 14.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ88328.1 - 0.033 14.1 0.2 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EAQ88328.1 - 0.036 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 EAQ88328.1 - 0.05 12.8 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 EAQ88328.1 - 0.06 12.7 0.1 0.27 10.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EAQ88328.1 - 0.068 12.8 0.2 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Archaeal ATPase PIF1 PF05970.9 EAQ88328.1 - 0.097 11.6 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase MobB PF03205.9 EAQ88328.1 - 0.11 12.2 0.4 0.2 11.3 0.3 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NAD_binding_1 PF00175.16 EAQ88329.1 - 1.5e-25 89.8 0.0 2.4e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EAQ88329.1 - 3.1e-14 52.8 0.0 5.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EAQ88329.1 - 1.9e-09 37.5 0.0 7.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EAQ88329.1 - 0.03 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DEAD PF00270.24 EAQ88330.1 - 5.8e-41 139.8 0.2 1.3e-40 138.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ88330.1 - 3.4e-16 58.8 0.0 7.6e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EAQ88330.1 - 3.9e-13 48.7 0.1 7.8e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EAQ88330.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Kelch_5 PF13854.1 EAQ88331.1 - 1.2e-12 47.5 7.7 4.1e-11 42.5 0.6 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 EAQ88331.1 - 1.4e-07 31.4 6.6 0.0002 21.4 0.1 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EAQ88331.1 - 2.9e-06 27.2 10.6 1.1 9.4 0.0 6.3 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EAQ88331.1 - 0.00051 19.6 2.8 14 5.6 0.0 5.7 6 0 0 6 6 6 0 Kelch motif Alpha_GJ PF03229.8 EAQ88331.1 - 0.0021 18.3 1.8 0.0045 17.3 1.2 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J Yip1 PF04893.12 EAQ88331.1 - 0.027 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain DUF533 PF04391.7 EAQ88331.1 - 0.03 13.7 0.1 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Herpes_gE PF02480.11 EAQ88331.1 - 0.061 11.5 0.0 0.094 10.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4328 PF14219.1 EAQ88331.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Phage_HK97_TLTM PF06120.6 EAQ88331.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Shisa PF13908.1 EAQ88331.1 - 0.15 12.2 1.2 0.23 11.6 0.8 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF605 PF04652.11 EAQ88331.1 - 0.15 11.4 10.0 0.21 10.9 7.0 1.1 1 0 0 1 1 1 0 Vta1 like Innate_immun PF12782.2 EAQ88331.1 - 0.22 10.7 5.5 0.47 9.6 3.8 1.5 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Kelch_4 PF13418.1 EAQ88331.1 - 0.26 11.1 21.0 0.093 12.5 0.7 6.0 4 2 1 5 5 5 0 Galactose oxidase, central domain SelP_N PF04592.9 EAQ88331.1 - 0.54 9.5 6.4 0.83 8.9 4.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sensor PF13796.1 EAQ88333.1 - 2.1 7.8 5.2 0.35 10.4 0.6 1.9 2 0 0 2 2 2 0 Putative sensor Ank_2 PF12796.2 EAQ88334.1 - 4.2e-62 206.4 3.9 2.6e-15 56.5 0.3 8.2 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ88334.1 - 9.3e-58 189.3 16.3 1.7e-10 40.1 0.0 14.3 14 0 0 14 14 14 10 Ankyrin repeat Ank_3 PF13606.1 EAQ88334.1 - 1.3e-41 136.4 16.2 2.5e-08 33.3 0.0 13.9 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 EAQ88334.1 - 2.1e-39 133.1 12.7 7e-07 29.6 0.0 9.5 7 2 3 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ88334.1 - 2.4e-31 107.0 13.8 2.6e-07 30.6 0.0 9.7 8 3 3 11 11 11 5 Ankyrin repeats (many copies) F-box-like PF12937.2 EAQ88334.1 - 0.00049 19.7 0.3 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like RVP PF00077.15 EAQ88334.1 - 0.15 11.9 0.4 1.1e+02 2.8 0.0 3.6 4 0 0 4 4 4 0 Retroviral aspartyl protease GLTP PF08718.6 EAQ88335.1 - 1.8e-46 157.8 0.1 8.8e-46 155.6 0.0 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PLDc PF00614.17 EAQ88336.1 - 5.7e-16 57.7 2.0 1e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EAQ88336.1 - 4.8e-12 45.7 0.0 6.4e-05 22.6 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain HET PF06985.6 EAQ88337.1 - 5.7e-23 81.6 0.0 1.4e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4611 PF15387.1 EAQ88337.1 - 0.73 10.0 6.7 7.5 6.7 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glyco_hydro_7 PF00840.15 EAQ88339.1 - 2.4e-18 65.7 0.0 4.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EAQ88339.1 - 1.9e-12 46.6 9.5 1.9e-12 46.6 6.6 2.8 4 0 0 4 4 4 1 Fungal cellulose binding domain adh_short PF00106.20 EAQ88340.1 - 8.5e-17 61.5 0.2 1.7e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ88340.1 - 5.5e-11 42.4 0.3 1.1e-10 41.5 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EAQ88340.1 - 0.037 14.0 0.2 0.073 13.0 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding SNF5 PF04855.7 EAQ88341.1 - 9.7e-86 287.1 0.0 1.3e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EAQ88341.1 - 4.5e-06 25.9 1.8 1.1e-05 24.6 1.3 1.8 1 0 0 1 1 1 1 GATA zinc finger DUF4139 PF13598.1 EAQ88343.1 - 1.6e-53 182.1 22.9 1.7e-42 145.8 0.2 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EAQ88343.1 - 1e-13 51.5 7.3 1e-13 51.5 5.1 4.0 3 2 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 EAQ88343.1 - 0.00041 20.5 13.5 0.00041 20.5 9.3 2.5 2 0 0 2 2 2 1 Nucleoporin FG repeat region GHBP PF12772.2 EAQ88345.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding Chitin_bind_3 PF03067.10 EAQ88346.1 - 2.4e-11 44.2 0.6 4.5e-08 33.5 0.1 2.3 1 1 0 2 2 2 2 Chitin binding domain Alpha-amylase PF00128.19 EAQ88347.1 - 2.1e-33 116.0 0.1 2.9e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EAQ88347.1 - 2.8e-12 46.5 0.1 7.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_61 PF03443.9 EAQ88348.1 - 3.1e-24 86.0 0.0 3.9e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pectate_lyase_3 PF12708.2 EAQ88349.1 - 2.1e-22 80.3 0.1 7.7e-22 78.5 0.0 2.1 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF3060 PF11259.3 EAQ88349.1 - 0.38 10.4 4.4 1.6 8.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) ABM PF03992.11 EAQ88351.1 - 0.0013 18.7 3.0 0.0079 16.2 0.0 2.8 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase tRNA-synt_1c PF00749.16 EAQ88352.1 - 8.2e-96 320.3 0.0 1.1e-95 319.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EAQ88352.1 - 2.6e-35 121.6 0.0 1.4e-34 119.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.16 EAQ88354.1 - 2.2e-36 124.3 0.1 3.4e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain ABC_tran PF00005.22 EAQ88355.1 - 6.8e-47 159.2 0.4 9.8e-23 80.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAQ88355.1 - 2.9e-15 56.0 1.1 5.9e-05 22.3 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ88355.1 - 7.2e-15 55.7 0.0 0.00072 19.6 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EAQ88355.1 - 7e-10 38.2 0.0 0.0012 18.3 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EAQ88355.1 - 1.7e-07 32.0 0.0 0.021 15.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAQ88355.1 - 2.2e-07 31.0 0.1 0.00051 20.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 EAQ88355.1 - 2.8e-07 31.0 8.7 0.0016 18.7 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.1 EAQ88355.1 - 3.1e-07 29.7 1.5 0.14 11.1 0.0 3.7 3 1 1 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 EAQ88355.1 - 3.3e-07 29.6 0.0 0.004 16.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EAQ88355.1 - 3.7e-07 30.2 0.2 0.0059 16.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EAQ88355.1 - 5.5e-07 29.5 0.1 0.008 16.1 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAQ88355.1 - 1.9e-06 27.8 0.0 0.00034 20.4 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EAQ88355.1 - 4.9e-06 27.0 0.1 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EAQ88355.1 - 7.4e-06 25.8 0.0 0.15 11.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EAQ88355.1 - 8e-06 24.8 0.2 0.11 11.2 0.0 2.8 3 0 0 3 3 2 2 ArgK protein AAA_10 PF12846.2 EAQ88355.1 - 2.6e-05 23.8 0.1 0.26 10.7 0.0 2.9 3 0 0 3 3 2 2 AAA-like domain AAA_18 PF13238.1 EAQ88355.1 - 3.3e-05 24.1 0.4 0.28 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EAQ88355.1 - 8.5e-05 22.2 0.0 0.49 10.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EAQ88355.1 - 8.6e-05 22.3 0.0 0.11 12.4 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EAQ88355.1 - 9.7e-05 21.8 0.1 0.12 11.9 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EAQ88355.1 - 0.00018 21.5 0.7 2.2 8.2 0.0 4.4 5 0 0 5 5 5 1 AAA ATPase domain NACHT PF05729.7 EAQ88355.1 - 0.00033 20.3 0.2 0.098 12.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EAQ88355.1 - 0.00038 20.5 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.12 EAQ88355.1 - 0.00039 20.3 0.2 0.21 11.3 0.1 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA PF00004.24 EAQ88355.1 - 0.00081 19.5 0.0 0.49 10.5 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAQ88355.1 - 0.0014 18.5 0.0 1.7 8.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 EAQ88355.1 - 0.0016 17.9 0.5 0.72 9.2 0.0 3.1 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EAQ88355.1 - 0.0026 17.2 0.5 0.78 9.1 0.0 3.5 4 1 0 4 4 4 1 FtsK/SpoIIIE family HEAT_2 PF13646.1 EAQ88355.1 - 0.0033 17.6 5.8 0.47 10.7 4.2 3.0 1 1 1 2 2 2 1 HEAT repeats AAA_25 PF13481.1 EAQ88355.1 - 0.0034 16.8 0.0 2.5 7.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain Septin PF00735.13 EAQ88355.1 - 0.0041 16.1 1.0 1.5 7.7 0.0 3.2 3 0 0 3 3 3 1 Septin ParcG PF10274.4 EAQ88355.1 - 0.0044 16.9 0.7 8.5 6.2 0.0 3.2 1 1 1 3 3 3 0 Parkin co-regulated protein Arch_ATPase PF01637.13 EAQ88355.1 - 0.0081 15.8 0.0 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase ATP-synt_ab PF00006.20 EAQ88355.1 - 0.0092 15.4 0.0 5 6.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EAQ88355.1 - 0.013 15.0 0.5 6.2 6.3 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EAQ88355.1 - 0.018 13.9 0.0 3.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 EAQ88355.1 - 0.028 13.1 0.0 1.5 7.3 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.12 EAQ88355.1 - 0.047 13.2 0.5 7.2 6.0 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PRK PF00485.13 EAQ88355.1 - 0.047 13.2 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MutS_V PF00488.16 EAQ88355.1 - 0.051 12.9 0.3 0.74 9.1 0.0 2.3 2 0 0 2 2 2 0 MutS domain V HEAT PF02985.17 EAQ88355.1 - 0.074 13.1 0.5 36 4.8 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.2 EAQ88355.1 - 0.095 12.5 0.0 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FeoB_N PF02421.13 EAQ88355.1 - 0.1 11.8 0.2 0.69 9.1 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_13 PF13166.1 EAQ88355.1 - 0.12 10.7 7.1 1.4 7.2 0.0 3.4 5 0 0 5 5 3 0 AAA domain HEAT_EZ PF13513.1 EAQ88355.1 - 9 6.9 9.8 14 6.3 0.4 4.9 5 1 1 6 6 4 0 HEAT-like repeat Glyco_hydro_12 PF01670.11 EAQ88356.1 - 7.3e-45 152.5 3.3 1.4e-44 151.6 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Methyltransf_2 PF00891.13 EAQ88358.1 - 4.7e-25 88.1 0.0 7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Fungal_trans PF04082.13 EAQ88359.1 - 7.7e-18 64.3 0.8 1.1e-17 63.7 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88359.1 - 4.5e-08 32.8 10.6 8.4e-08 32.0 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ88360.1 - 2.9e-20 72.2 0.0 4.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88360.1 - 1.7e-08 34.2 8.9 3.4e-08 33.2 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 EAQ88360.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain DivIC PF04977.10 EAQ88360.1 - 0.23 10.9 0.2 0.43 10.0 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator TPR_9 PF13371.1 EAQ88361.1 - 0.00028 20.6 0.4 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Cytochrom_B561 PF03188.11 EAQ88362.1 - 0.00019 21.2 4.0 0.00019 21.2 2.8 2.1 1 1 0 2 2 2 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EAQ88362.1 - 0.0032 16.8 8.7 0.0032 16.8 6.0 2.9 1 1 3 4 4 4 1 Cytochrome b(N-terminal)/b6/petB YajC PF02699.10 EAQ88362.1 - 0.014 15.0 0.2 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit EphA2_TM PF14575.1 EAQ88362.1 - 0.021 15.2 1.0 0.25 11.7 0.0 2.9 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain GpcrRhopsn4 PF10192.4 EAQ88362.1 - 0.044 12.9 0.4 0.082 12.0 0.3 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF2417 PF10329.4 EAQ88362.1 - 0.45 9.8 4.1 3.5 6.9 0.0 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) O-antigen_lig PF13425.1 EAQ88362.1 - 0.48 10.4 5.5 3.4 7.6 0.2 2.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Ni_hydr_CYTB PF01292.15 EAQ88362.1 - 1.4 8.2 12.7 1.3 8.3 4.7 2.9 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 DUF2207 PF09972.4 EAQ88362.1 - 5.7 5.4 5.8 39 2.6 4.0 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_3 PF07859.8 EAQ88363.1 - 2.2e-12 47.0 0.0 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Frigida PF07899.6 EAQ88364.1 - 0.14 10.8 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein TMEM154 PF15102.1 EAQ88365.1 - 0.0017 18.0 2.1 0.0019 17.9 0.0 2.0 1 1 1 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.1 EAQ88365.1 - 0.024 15.0 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EAQ88365.1 - 0.037 12.2 0.1 0.037 12.2 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DDE_1 PF03184.14 EAQ88366.1 - 4.8e-46 156.6 0.0 7.6e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ88366.1 - 2.1e-12 46.3 0.0 4.1e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EAQ88366.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D zf-CCHC PF00098.18 EAQ88366.1 - 0.057 13.3 1.1 0.11 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF904 PF06005.7 EAQ88366.1 - 0.064 13.5 1.7 0.38 11.0 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) zf-CCHC_4 PF14392.1 EAQ88366.1 - 0.075 12.7 1.9 0.15 11.7 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle PPR_2 PF13041.1 EAQ88369.1 - 8.2e-44 147.3 5.9 5e-09 35.9 0.0 14.4 11 3 5 17 17 17 9 PPR repeat family PPR_3 PF13812.1 EAQ88369.1 - 3.5e-24 83.0 21.0 0.00039 20.4 0.0 14.8 17 0 0 17 17 17 6 Pentatricopeptide repeat domain PPR PF01535.15 EAQ88369.1 - 9.3e-23 78.5 21.7 0.00031 20.4 0.0 13.1 16 0 0 16 16 16 5 PPR repeat PPR_1 PF12854.2 EAQ88369.1 - 5.5e-17 60.9 0.2 1.8e-08 33.7 0.0 8.2 9 0 0 9 9 9 2 PPR repeat RPM2 PF08579.6 EAQ88369.1 - 0.00014 21.9 0.0 0.0061 16.6 0.0 3.6 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EAQ88369.1 - 0.036 13.4 0.5 2.7 7.3 0.2 3.1 2 1 1 3 3 3 0 Mitochondrial ATPase expression GHMP_kinases_N PF00288.21 EAQ88370.1 - 6.2e-16 58.2 0.9 2.2e-15 56.4 0.6 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EAQ88370.1 - 7.9e-08 32.3 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal SOBP PF15279.1 EAQ88371.1 - 0.058 13.7 0.1 0.082 13.2 0.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Innate_immun PF12782.2 EAQ88371.1 - 0.83 8.8 13.1 2.7 7.1 5.7 2.4 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Aldedh PF00171.17 EAQ88372.1 - 6.6e-133 443.4 0.0 7.4e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EAQ88372.1 - 1.5e-06 27.2 0.0 2.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RRM_1 PF00076.17 EAQ88373.1 - 1.3e-08 34.3 0.0 4.8e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ88373.1 - 1.9e-08 34.1 0.0 5.9e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ88373.1 - 6.2e-05 22.7 0.1 0.00077 19.2 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 EAQ88373.1 - 0.065 11.1 9.3 0.075 10.9 6.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAQ88373.1 - 1.8 6.5 4.6 1.7 6.5 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NMD3 PF04981.8 EAQ88374.1 - 1.2e-70 237.3 3.9 2.2e-70 236.4 2.7 1.5 1 0 0 1 1 1 1 NMD3 family TPR_11 PF13414.1 EAQ88374.1 - 5.4e-13 48.3 3.0 1.9e-12 46.6 0.3 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EAQ88374.1 - 1.8e-05 24.1 0.1 0.13 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88374.1 - 0.00011 22.1 1.2 0.00026 20.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88374.1 - 0.00019 21.1 5.0 0.038 13.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ88374.1 - 0.0047 16.6 1.2 3.3 7.7 0.1 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ88374.1 - 0.026 14.6 0.2 0.083 13.0 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ead_Ea22 PF13935.1 EAQ88374.1 - 0.044 14.1 6.5 1.4 9.2 1.6 2.6 2 0 0 2 2 2 0 Ead/Ea22-like protein DUF2413 PF10310.4 EAQ88374.1 - 0.054 12.3 8.1 0.097 11.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF35_N PF12172.3 EAQ88374.1 - 0.073 13.0 2.8 0.097 12.6 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.16 EAQ88374.1 - 3 7.8 6.2 5.3 7.0 1.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger HAD_2 PF13419.1 EAQ88375.1 - 6.1e-07 29.8 0.0 0.00061 20.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 EAQ88376.1 - 2.5e-18 65.8 0.0 4.4e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ88376.1 - 1.1e-12 48.9 0.0 2.9e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ88376.1 - 3.2e-07 30.0 0.2 1.2e-05 25.0 0.0 2.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EAQ88376.1 - 1.6e-06 27.8 11.7 1.6e-06 27.8 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ88376.1 - 5.9e-05 21.8 0.1 9e-05 21.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 EAQ88377.1 - 2.6e-13 49.2 0.7 0.0056 16.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Acyltransferase PF01553.16 EAQ88378.1 - 1.2e-18 66.8 0.0 3.1e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 EAQ88379.1 - 3.9e-23 80.9 0.4 6.2e-23 80.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Pantoate_ligase PF02569.10 EAQ88380.1 - 3.3e-32 111.3 0.0 8.5e-32 110.0 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Peptidase_S10 PF00450.17 EAQ88381.1 - 1.6e-47 162.6 0.0 3.1e-47 161.6 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.16 EAQ88381.1 - 0.0046 16.2 0.0 0.038 13.2 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Tmemb_14 PF03647.8 EAQ88383.1 - 0.023 15.0 1.0 0.44 10.9 0.0 2.2 1 1 1 2 2 2 0 Transmembrane proteins 14C ZipA_C PF04354.8 EAQ88383.1 - 0.036 13.5 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain DUF1772 PF08592.6 EAQ88383.1 - 0.051 13.3 0.7 0.07 12.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3824 PF12868.2 EAQ88383.1 - 0.052 14.4 2.6 0.069 14.0 1.8 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) RE_XamI PF09572.5 EAQ88383.1 - 0.12 11.7 0.7 0.15 11.4 0.5 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease PUA PF01472.15 EAQ88384.1 - 1.5e-13 50.2 0.4 3.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 PUA domain Borealin PF10512.4 EAQ88384.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Inhibitor_I78 PF11720.3 EAQ88385.1 - 3.9e-11 42.5 0.0 4.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EAQ88385.1 - 0.00074 19.6 0.1 0.001 19.1 0.1 1.4 1 1 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.3 EAQ88385.1 - 0.021 14.8 0.1 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) NST1 PF13945.1 EAQ88388.1 - 1.7e-58 197.8 0.1 1.7e-58 197.8 0.1 4.6 2 2 2 4 4 4 1 Salt tolerance down-regulator CD20 PF04103.10 EAQ88389.1 - 0.059 13.2 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 CD20-like family Ras PF00071.17 EAQ88390.1 - 4.4e-46 156.2 0.0 5.2e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ88390.1 - 3.7e-15 56.4 0.0 5.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ88390.1 - 5.2e-06 25.8 0.0 7.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAQ88390.1 - 0.023 13.8 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EAQ88390.1 - 0.05 13.1 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EAQ88390.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 EAQ88391.1 - 5.6e-07 29.5 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GATase_5 PF13507.1 EAQ88392.1 - 2e-95 318.6 0.0 3.2e-95 317.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EAQ88392.1 - 2.9e-29 102.0 3.0 4.5e-17 62.4 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EAQ88392.1 - 3.8e-18 65.5 0.4 2.7e-17 62.7 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TPR_11 PF13414.1 EAQ88393.1 - 1.4e-18 66.2 9.9 2.1e-15 56.0 4.2 2.3 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EAQ88393.1 - 1.5e-15 56.0 6.9 1.5e-06 27.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88393.1 - 7.2e-13 47.3 10.1 9.6e-05 22.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ88393.1 - 4.7e-09 36.6 17.9 5e-05 23.8 2.0 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ88393.1 - 6.2e-08 32.2 5.4 0.0016 18.4 0.2 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ88393.1 - 1.5e-07 30.6 1.6 0.0061 16.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ88393.1 - 2.8e-06 27.4 11.3 0.032 14.8 0.3 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88393.1 - 3.8e-06 26.7 7.5 0.0054 16.6 0.9 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ88393.1 - 0.00052 20.2 7.2 0.00055 20.2 2.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ88393.1 - 0.0012 18.6 6.5 0.35 10.8 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ88393.1 - 0.0027 17.3 2.2 0.11 12.3 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ88393.1 - 0.0068 16.2 3.6 0.0068 16.2 2.5 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 EAQ88393.1 - 0.0075 15.7 2.3 0.014 14.8 1.6 1.4 1 0 0 1 1 1 1 XPC-binding domain BTAD PF03704.12 EAQ88393.1 - 0.023 14.9 4.3 1.3 9.2 1.1 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EAQ88393.1 - 0.18 12.3 8.4 4 8.1 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Med3 PF11593.3 EAQ88393.1 - 4.7 6.3 9.4 8.2 5.5 6.5 1.5 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2057 PF09829.4 EAQ88393.1 - 7.6 6.1 6.4 2.4 7.7 2.2 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) RINGv PF12906.2 EAQ88394.1 - 0.02 14.9 6.4 0.035 14.1 4.4 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EAQ88394.1 - 0.19 11.7 4.8 0.32 10.9 3.3 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain GalKase_gal_bdg PF10509.4 EAQ88396.1 - 1.1e-19 69.3 0.0 2.2e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EAQ88396.1 - 5.2e-15 55.2 1.1 2.1e-14 53.3 0.7 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EAQ88396.1 - 7.6e-11 42.0 0.1 1.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal TPP_enzyme_C PF02775.16 EAQ88397.1 - 1.3e-50 170.9 1.1 1.3e-49 167.7 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EAQ88397.1 - 8.9e-50 168.5 0.4 8.9e-50 168.5 0.3 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAQ88397.1 - 1e-37 128.9 1.6 3.4e-37 127.2 0.3 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF605 PF04652.11 EAQ88398.1 - 2.8 7.2 37.0 3.4 6.9 25.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3659 PF12396.3 EAQ88400.1 - 2e-13 49.7 7.7 5.1e-10 38.8 0.8 3.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3659) Transferase PF02458.10 EAQ88402.1 - 9.8e-18 63.7 0.0 1.2e-16 60.2 0.0 2.2 1 1 0 1 1 1 1 Transferase family SNF2_N PF00176.18 EAQ88403.1 - 7.8e-67 225.1 0.0 1.3e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EAQ88403.1 - 6.2e-11 41.7 12.6 2.9e-09 36.4 8.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ88403.1 - 9e-10 38.4 19.3 5e-09 36.0 10.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ88403.1 - 3.5e-09 36.3 14.0 9.3e-09 34.9 9.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAQ88403.1 - 6.8e-08 32.2 11.9 1.5e-07 31.1 8.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAQ88403.1 - 9.9e-08 31.5 15.0 9.9e-08 31.5 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ88403.1 - 5.3e-07 29.2 12.4 5.3e-07 29.2 8.6 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Helicase_C PF00271.26 EAQ88403.1 - 3.8e-05 23.4 0.1 0.00034 20.4 0.0 2.4 1 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.2 EAQ88403.1 - 0.00059 19.8 10.8 0.002 18.2 7.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EAQ88403.1 - 0.00083 19.0 13.9 0.001 18.7 7.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EAQ88403.1 - 0.0011 18.4 7.6 0.0029 17.1 5.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain U-box PF04564.10 EAQ88403.1 - 0.0037 17.2 1.3 0.015 15.2 0.1 2.6 2 0 0 2 2 2 1 U-box domain zf-RING_6 PF14835.1 EAQ88403.1 - 0.0069 16.1 5.6 0.017 14.9 3.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EAQ88403.1 - 0.0076 16.0 4.2 0.027 14.2 2.9 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EAQ88403.1 - 0.016 14.6 0.4 5.4 6.5 0.0 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif HIRAN PF08797.6 EAQ88403.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain zf-P11 PF03854.9 EAQ88403.1 - 0.12 11.8 8.2 2.6 7.6 2.9 2.6 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.2 EAQ88403.1 - 0.5 10.2 5.8 1.9 8.3 4.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon DUF1644 PF07800.7 EAQ88403.1 - 0.72 9.7 7.3 4.7 7.0 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) NmrA PF05368.8 EAQ88404.1 - 6.6e-11 41.9 0.0 1.4e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ88404.1 - 5e-07 29.8 0.1 1.1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Glyco_hydro_61 PF03443.9 EAQ88405.1 - 7.3e-46 156.7 0.0 8.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.16 EAQ88406.1 - 2.5e-28 97.8 0.0 2.8e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 EAQ88407.1 - 1.7e-59 201.1 0.0 3.4e-59 200.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88407.1 - 3.5e-21 75.4 0.0 8.5e-21 74.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EAQ88407.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 EAQ88408.1 - 1e-25 88.9 0.0 2.6e-25 87.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EAQ88408.1 - 3e-24 84.9 1.2 5.7e-24 84.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EAQ88409.1 - 7.9e-133 442.4 0.2 9.4e-133 442.1 0.2 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EAQ88409.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 Hydroxyneurosporene synthase (CrtC) Histone PF00125.19 EAQ88410.1 - 1.1e-09 38.2 0.8 1.5e-09 37.8 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAQ88410.1 - 0.027 14.5 1.9 0.055 13.5 0.1 2.0 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4400 PF14348.1 EAQ88410.1 - 0.055 12.8 0.2 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PCP_red PF08369.5 EAQ88410.1 - 0.075 12.9 1.9 0.12 12.2 0.3 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Acetyltransf_1 PF00583.19 EAQ88411.1 - 0.0013 18.7 0.3 0.0025 17.7 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ88411.1 - 0.061 13.4 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAQ88411.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pho86 PF11124.3 EAQ88411.1 - 0.15 11.0 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DDE_1 PF03184.14 EAQ88412.1 - 6.4e-46 156.2 0.0 1e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ88412.1 - 2.2e-12 46.3 0.0 4.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ88412.1 - 2.8e-09 36.6 0.1 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ88412.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D zf-CCHC PF00098.18 EAQ88412.1 - 0.06 13.2 1.1 0.11 12.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF904 PF06005.7 EAQ88412.1 - 0.065 13.5 1.6 0.39 11.0 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) zf-CCHC_4 PF14392.1 EAQ88412.1 - 0.079 12.6 1.9 0.15 11.7 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle AOX PF01786.12 EAQ88413.1 - 1.2e-85 286.0 0.0 1.5e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-H2C2_2 PF13465.1 EAQ88414.1 - 9.7e-14 50.8 9.0 6.9e-08 32.4 0.2 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ88414.1 - 8.5e-12 44.6 11.8 1.1e-05 25.5 1.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ88414.1 - 8.4e-09 35.1 18.6 5.1e-05 23.3 1.8 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ88414.1 - 5.2e-07 29.6 1.8 0.039 14.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ88414.1 - 7.5e-05 22.7 1.3 0.018 15.2 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EAQ88414.1 - 0.12 12.6 0.8 0.24 11.7 0.6 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.17 EAQ88414.1 - 1.8 8.7 3.3 11 6.1 2.3 2.1 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EAQ88414.1 - 3.3 7.7 9.7 14 5.7 0.4 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger ADH_zinc_N PF00107.21 EAQ88415.1 - 2.4e-09 36.8 0.0 4.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ88415.1 - 6.1e-06 25.9 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DHDPS PF00701.17 EAQ88416.1 - 0.027 13.0 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 EAQ88418.1 - 4.7e-47 160.4 22.0 6.5e-47 159.9 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88418.1 - 1.2e-09 37.3 10.5 1.2e-09 37.3 7.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ88418.1 - 6.5e-06 24.6 5.3 9.2e-06 24.1 3.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Syntaxin-18_N PF10496.4 EAQ88419.1 - 7.5e-16 57.7 0.9 1.4e-15 56.8 0.1 2.0 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DAGK_cat PF00781.19 EAQ88420.1 - 8.5e-27 93.1 0.0 1.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 EAQ88421.1 - 6.4e-41 140.1 0.2 8.5e-41 139.7 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 EAQ88421.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Aminotran_1_2 PF00155.16 EAQ88422.1 - 1.6e-55 188.5 0.0 1.9e-35 122.5 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II NARP1 PF12569.3 EAQ88423.1 - 6e-186 619.2 22.9 2.3e-155 518.2 4.7 3.4 2 2 1 3 3 3 3 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EAQ88423.1 - 1.2e-22 79.9 35.5 0.00021 21.8 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ88423.1 - 6.4e-22 77.6 24.8 1.9e-05 24.8 0.0 7.4 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ88423.1 - 1.7e-21 75.6 34.4 2.3e-06 27.1 0.2 7.9 8 1 0 8 8 8 5 TPR repeat TPR_14 PF13428.1 EAQ88423.1 - 1.8e-18 65.3 25.0 0.00064 20.1 0.0 11.2 6 4 5 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ88423.1 - 2.6e-14 52.8 14.1 0.00081 19.1 0.0 7.6 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ88423.1 - 4.7e-14 51.3 16.4 0.00054 19.9 0.0 9.5 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88423.1 - 1.3e-13 49.6 48.2 0.00054 19.6 0.1 11.5 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88423.1 - 1.8e-10 40.6 26.7 0.016 15.1 0.0 8.5 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ88423.1 - 2.8e-10 39.3 32.3 1.7e-05 24.1 0.1 10.0 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ88423.1 - 2.3e-09 36.3 17.5 0.0029 17.2 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAQ88423.1 - 1.1e-05 25.1 7.0 1.7 8.5 0.1 5.6 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EAQ88423.1 - 5.5e-05 22.8 0.5 0.49 10.2 0.1 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ88423.1 - 0.00023 20.7 18.2 4.3 7.3 0.0 8.9 9 1 1 10 10 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ88423.1 - 0.0037 17.1 19.1 1.2 9.1 0.0 7.4 9 0 0 9 9 9 2 Tetratricopeptide repeat PPTA PF01239.17 EAQ88423.1 - 0.0053 16.0 0.7 2.5 7.5 0.0 3.9 4 0 0 4 4 4 1 Protein prenyltransferase alpha subunit repeat TPR_4 PF07721.9 EAQ88423.1 - 0.0064 16.8 13.8 7.1 7.3 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat Mgr1 PF08602.5 EAQ88423.1 - 0.092 11.7 0.4 0.21 10.5 0.3 1.5 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Zn_clus PF00172.13 EAQ88424.1 - 0.04 13.8 3.7 0.071 13.0 2.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EAQ88424.1 - 4.2 5.5 5.9 5.6 5.1 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 2-Hacid_dh_C PF02826.14 EAQ88425.1 - 9.6e-57 190.9 0.0 1.3e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ88425.1 - 3.2e-17 62.2 0.0 6.2e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAQ88425.1 - 3.5e-06 26.9 0.2 6.2e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EAQ88425.1 - 0.0027 17.1 0.1 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EAQ88425.1 - 0.016 15.0 0.0 0.066 13.0 0.0 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 EAQ88426.1 - 3.3e-139 462.3 0.4 3.8e-139 462.1 0.3 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EAQ88426.1 - 1.3e-82 275.4 3.0 2e-82 274.8 2.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EAQ88426.1 - 9.8e-06 24.8 0.1 2.2e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EAQ88426.1 - 0.00066 19.0 0.3 0.0012 18.2 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 EAQ88426.1 - 0.014 15.0 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 EAQ88426.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 EAQ88426.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ig PF00047.20 EAQ88426.1 - 0.066 13.3 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain JAB PF01398.16 EAQ88427.1 - 0.0002 21.0 0.2 0.0035 17.0 0.2 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Glycogen_syn PF05693.8 EAQ88428.1 - 0.015 13.5 0.0 0.018 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase TMEM210 PF15195.1 EAQ88428.1 - 0.038 14.1 0.1 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 TMEM210 family Mito_carr PF00153.22 EAQ88429.1 - 3.2e-47 158.1 2.8 5.9e-18 64.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 EAQ88430.1 - 4.1e-06 26.3 1.6 0.0013 18.3 0.0 2.8 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EAQ88430.1 - 0.0004 20.2 5.0 0.26 11.2 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88430.1 - 0.015 15.1 3.2 22 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ88430.1 - 0.019 15.2 0.2 8.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ88430.1 - 0.079 13.6 2.5 52 4.8 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EAQ88431.1 - 1.5e-18 66.7 28.9 2.6e-16 59.3 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EAQ88431.1 - 7.6 4.9 9.7 0.89 7.9 2.2 2.3 1 1 1 2 2 2 0 Reduced folate carrier Fungal_trans PF04082.13 EAQ88432.1 - 7.1e-24 84.0 0.0 1.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBP_like PF12727.2 EAQ88432.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain Tyrosinase PF00264.15 EAQ88433.1 - 2.1e-37 129.4 0.0 3.4e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 EAQ88436.1 - 4.3e-23 81.6 30.8 6.6e-22 77.6 9.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Mucin PF01456.12 EAQ88437.1 - 0.0032 17.2 15.8 0.0055 16.4 10.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein RVT_1 PF00078.22 EAQ88438.1 - 4.3e-24 85.0 0.0 7.6e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ88438.1 - 3.9e-15 56.0 0.0 1.2e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ88438.1 - 6.6e-06 25.7 0.0 1.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EAQ88438.1 - 0.0055 16.0 0.0 0.02 14.2 0.0 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Gag_p24 PF00607.15 EAQ88438.1 - 0.01 15.4 0.2 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Herpes_Helicase PF02689.9 EAQ88440.1 - 0.00028 18.7 0.0 0.00032 18.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ88440.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain LIN37 PF15306.1 EAQ88442.1 - 0.021 14.8 0.8 0.037 14.0 0.5 1.6 1 1 0 1 1 1 0 LIN37 ORC6 PF05460.8 EAQ88442.1 - 0.14 11.2 1.1 0.15 11.1 0.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HTH_psq PF05225.11 EAQ88443.1 - 6.2e-16 57.6 0.0 1.3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ88443.1 - 1.5e-15 56.7 0.0 3.9e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EAQ88443.1 - 3.8e-09 36.0 0.1 6.5e-05 22.1 0.0 2.9 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_23 PF13384.1 EAQ88443.1 - 0.00065 19.2 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 EAQ88443.1 - 0.0037 16.6 0.1 0.0089 15.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.7 EAQ88443.1 - 0.0092 15.4 0.1 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.1 EAQ88443.1 - 0.014 15.4 0.1 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EAQ88443.1 - 0.046 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MerR_1 PF13411.1 EAQ88443.1 - 0.068 12.9 0.2 5.3 6.8 0.0 3.2 3 0 0 3 3 3 0 MerR HTH family regulatory protein MULE PF10551.4 EAQ88444.1 - 3.1e-18 65.7 0.2 9.9e-18 64.0 0.2 1.9 1 0 0 1 1 1 1 MULE transposase domain zf-CCHC_6 PF15288.1 EAQ88444.1 - 0.0014 18.2 0.3 0.0035 16.9 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Mito_fiss_reg PF05308.6 EAQ88444.1 - 0.1 11.9 1.9 0.18 11.1 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator RgpF PF05045.7 EAQ88444.1 - 0.12 10.9 0.3 0.17 10.3 0.2 1.1 1 0 0 1 1 1 0 Rhamnan synthesis protein F DDE_1 PF03184.14 EAQ88445.1 - 3.1e-47 160.5 0.0 5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ88445.1 - 9.5e-14 50.6 0.0 2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ88445.1 - 2.8e-09 36.6 0.1 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ88445.1 - 0.024 14.5 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D DUF1087 PF06465.8 EAQ88445.1 - 0.037 13.9 1.4 0.36 10.7 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF904 PF06005.7 EAQ88445.1 - 0.072 13.3 2.2 0.8 10.0 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DDE_1 PF03184.14 EAQ88446.1 - 6.1e-32 110.5 0.0 2.4e-26 92.2 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ88446.1 - 0.0025 17.3 0.0 0.0066 15.9 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF904 PF06005.7 EAQ88446.1 - 0.023 14.9 0.4 0.075 13.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF2702 PF10863.3 EAQ88446.1 - 0.062 13.0 0.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2702) DDE_1 PF03184.14 EAQ88448.1 - 0.0015 17.6 0.1 0.092 11.8 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease RVT_1 PF00078.22 EAQ88449.1 - 1.9e-24 86.2 0.0 3.7e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ88449.1 - 1.7e-15 57.2 0.0 5.5e-15 55.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EAQ88449.1 - 1.9e-11 43.4 0.1 6.4e-11 41.7 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EAQ88449.1 - 0.00016 21.0 0.0 0.00047 19.5 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-CCHC PF00098.18 EAQ88449.1 - 0.00017 21.3 3.9 0.00038 20.2 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle IncA PF04156.9 EAQ88449.1 - 0.0028 17.2 1.6 0.0028 17.2 1.1 3.0 3 0 0 3 3 3 1 IncA protein FlaC_arch PF05377.6 EAQ88449.1 - 0.27 11.1 4.1 1.2 9.0 0.2 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CorA PF01544.13 EAQ88449.1 - 0.34 9.9 2.3 1 8.3 1.6 1.8 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4446 PF14584.1 EAQ88449.1 - 0.93 9.3 3.1 0.91 9.3 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Retrotrans_gag PF03732.12 EAQ88449.1 - 3.6 7.7 11.2 0.085 12.9 0.2 3.7 4 0 0 4 4 4 0 Retrotransposon gag protein TauD PF02668.11 EAQ88450.1 - 2.6e-35 122.3 0.0 2e-34 119.4 0.0 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSP_C PF05735.7 EAQ88450.1 - 0.034 13.7 0.3 0.064 12.8 0.2 1.4 1 0 0 1 1 1 0 Thrombospondin C-terminal region MFS_1 PF07690.11 EAQ88451.1 - 1.1e-08 34.1 7.1 1.1e-08 34.1 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Rib_5-P_isom_A PF06026.9 EAQ88452.1 - 2.3e-40 137.7 0.0 3.6e-39 133.8 0.0 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EAQ88452.1 - 0.034 13.7 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Fungal_trans PF04082.13 EAQ88454.1 - 2.4e-11 42.9 0.0 4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88454.1 - 1.3e-05 25.0 7.7 2.2e-05 24.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKD_channel PF08016.7 EAQ88455.1 - 0.00041 18.9 17.9 0.02 13.3 12.4 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EAQ88455.1 - 0.0054 16.0 19.9 0.34 10.1 13.8 2.3 1 1 0 1 1 1 1 Ion transport protein Sec2p PF06428.6 EAQ88455.1 - 0.015 15.1 1.7 0.027 14.2 1.1 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p TBPIP PF07106.8 EAQ88455.1 - 0.087 12.3 1.2 0.14 11.6 0.8 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 PF01166.13 EAQ88455.1 - 0.099 12.6 2.0 0.28 11.1 1.4 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family AAA PF00004.24 EAQ88456.1 - 4.3e-15 56.0 0.1 1.4e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EAQ88456.1 - 0.00011 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EAQ88456.1 - 0.0023 18.0 0.7 0.052 13.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ88456.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EAQ88456.1 - 0.013 16.2 0.8 0.049 14.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAQ88456.1 - 0.4 10.6 4.0 0.12 12.4 0.2 2.2 2 1 0 2 2 2 0 AAA ATPase domain GOLD_2 PF13897.1 EAQ88456.1 - 3.1 8.0 13.0 7.2 6.8 0.6 4.2 3 1 1 4 4 4 0 Golgi-dynamics membrane-trafficking Methyltransf_10 PF05971.7 EAQ88458.1 - 3.6e-39 134.6 0.2 2.9e-19 69.3 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF890) XAP5 PF04921.9 EAQ88459.1 - 3.8e-86 288.5 0.1 6.3e-86 287.8 0.0 1.3 2 0 0 2 2 2 1 XAP5, circadian clock regulator Herpes_Helicase PF02689.9 EAQ88462.1 - 0.00028 18.7 0.0 0.00032 18.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ88462.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Dynamin_N PF00350.18 EAQ88463.1 - 3.9e-32 111.3 0.0 7.9e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAQ88463.1 - 3.9e-21 75.1 0.3 3.3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EAQ88463.1 - 0.0004 20.3 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ88463.1 - 0.0062 17.0 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein GED PF02212.13 EAQ88463.1 - 0.0074 16.1 0.2 0.13 12.2 0.0 3.0 3 0 0 3 3 3 1 Dynamin GTPase effector domain DUF965 PF06135.7 EAQ88463.1 - 0.011 15.7 0.0 0.039 13.9 0.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) Med9 PF07544.8 EAQ88463.1 - 0.012 15.2 1.4 0.052 13.2 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin PF00804.20 EAQ88463.1 - 0.034 14.2 1.1 0.17 12.0 0.0 2.7 3 1 0 3 3 3 0 Syntaxin TINF2_N PF14973.1 EAQ88463.1 - 0.057 13.5 4.3 0.32 11.1 0.1 3.3 1 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus AAA_21 PF13304.1 EAQ88463.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAQ88463.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ88463.1 - 0.18 12.0 0.4 0.89 9.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain RVT_1 PF00078.22 EAQ88464.1 - 5.7e-08 32.3 0.0 2.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_binding_4 PF07993.7 EAQ88465.1 - 0.00039 19.4 0.0 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EAQ88465.1 - 0.034 14.1 0.1 0.075 13.0 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EAQ88465.1 - 0.058 13.3 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EAQ88465.1 - 0.061 12.7 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GMC_oxred_C PF05199.8 EAQ88466.1 - 1.1e-32 113.3 0.0 1.7e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAQ88466.1 - 2.3e-29 102.4 0.0 5.4e-27 94.7 0.0 2.8 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EAQ88466.1 - 0.00099 19.0 0.1 0.0039 17.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ88466.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ88466.1 - 0.025 13.4 0.2 0.06 12.1 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EAQ88466.1 - 0.1 12.6 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dimer_Tnp_hAT PF05699.9 EAQ88467.1 - 2.6e-20 71.8 1.0 6.3e-20 70.5 0.7 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region COX8 PF02285.10 EAQ88468.1 - 0.71 9.4 0.0 0.71 9.4 0.0 2.7 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII ADH_zinc_N_2 PF13602.1 EAQ88469.1 - 7.7e-24 85.0 0.0 1.1e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EAQ88469.1 - 4.2e-17 61.9 0.1 6.5e-17 61.2 0.1 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase YjeF_N PF03853.10 EAQ88469.1 - 0.037 13.6 0.2 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF2011 PF09428.5 EAQ88470.1 - 0.012 15.5 6.0 0.018 14.9 4.1 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DDHD PF02862.12 EAQ88470.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF4207 PF13904.1 EAQ88470.1 - 0.27 10.5 7.6 0.36 10.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Esterase_phd PF10503.4 EAQ88471.1 - 1.7e-24 86.3 1.3 2.2e-24 85.9 0.9 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EAQ88471.1 - 3e-09 36.4 2.2 4.6e-09 35.8 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ88471.1 - 1.4e-06 28.1 0.4 1.8e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EAQ88471.1 - 0.00026 20.5 0.7 0.00041 19.8 0.5 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EAQ88471.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAQ88471.1 - 0.0024 16.6 4.2 0.0069 15.1 0.5 2.1 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.15 EAQ88471.1 - 0.0051 16.4 0.3 0.0074 15.8 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAQ88471.1 - 0.015 14.7 0.1 0.03 13.7 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EAQ88471.1 - 0.026 14.0 0.3 0.05 13.1 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 EAQ88471.1 - 0.071 12.8 0.2 0.19 11.3 0.1 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4587 PF15248.1 EAQ88472.1 - 6.2 7.4 13.2 0.16 12.5 1.1 4.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4587) AOX PF01786.12 EAQ88474.1 - 1.5e-69 233.5 0.0 1.8e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase FATC PF02260.15 EAQ88474.1 - 0.092 12.2 0.1 0.25 10.7 0.1 1.8 1 0 0 1 1 1 0 FATC domain Alpha_GJ PF03229.8 EAQ88475.1 - 2.1 8.6 7.2 3.6 7.9 5.0 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Herpes_BLLF1 PF05109.8 EAQ88475.1 - 3.6 5.4 11.6 4.4 5.1 8.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Elongin_A PF06881.6 EAQ88475.1 - 8.8 6.7 9.7 57 4.1 6.4 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RVT_1 PF00078.22 EAQ88476.1 - 6.2e-27 94.3 0.0 1.2e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ88476.1 - 4e-21 74.8 0.0 3.5e-20 71.7 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ88476.1 - 9.6e-09 35.5 0.1 1.9e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ88476.1 - 0.0078 16.5 4.2 0.081 13.3 0.7 2.9 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ88476.1 - 0.064 12.2 1.9 0.13 11.2 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mnd1 PF03962.10 EAQ88476.1 - 0.27 10.8 1.4 0.65 9.6 1.0 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4226 PF10774.4 EAQ88476.1 - 0.49 10.4 6.4 0.12 12.3 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF4419 PF14388.1 EAQ88477.1 - 4.7e-93 311.6 0.0 5.7e-93 311.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF1173 PF06666.6 EAQ88477.1 - 0.04 12.7 0.1 0.058 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Myosin_tail_1 PF01576.14 EAQ88478.1 - 4.2e-05 21.5 66.1 0.0035 15.1 16.1 2.1 1 1 1 2 2 2 2 Myosin tail Spc7 PF08317.6 EAQ88478.1 - 0.00011 21.0 17.7 0.00011 21.0 12.3 3.0 2 2 0 2 2 2 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EAQ88478.1 - 0.00085 18.5 8.6 0.00085 18.5 6.0 3.0 1 1 2 3 3 3 2 Reovirus sigma C capsid protein IncA PF04156.9 EAQ88478.1 - 0.0033 17.0 17.0 0.0033 17.0 11.8 4.0 1 1 4 5 5 5 3 IncA protein DUF2968 PF11180.3 EAQ88478.1 - 0.0036 16.7 13.8 0.0036 16.7 9.6 3.7 1 1 3 4 4 3 1 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 EAQ88478.1 - 0.0044 16.8 13.8 0.0044 16.8 9.6 4.5 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 EAQ88478.1 - 0.0077 16.5 14.1 0.0077 16.5 9.8 3.9 1 1 2 3 3 2 1 Striatin family Fib_alpha PF08702.5 EAQ88478.1 - 0.0078 16.3 8.5 0.0078 16.3 5.9 4.2 4 2 0 4 4 4 1 Fibrinogen alpha/beta chain family M_domain PF12938.2 EAQ88478.1 - 0.084 12.6 3.8 0.24 11.1 2.6 1.7 1 0 0 1 1 1 0 M domain of GW182 ADIP PF11559.3 EAQ88478.1 - 2.9 7.7 49.8 0.042 13.7 7.4 4.8 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EAQ88478.1 - 4.5 5.6 51.8 0.35 9.2 15.8 2.8 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 EAQ88478.1 - 5.7 6.0 52.0 0.017 14.2 10.7 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding RTBV_P46 PF06216.6 EAQ88478.1 - 8.7 5.0 11.8 4.2 6.1 0.8 3.1 2 1 0 3 3 3 0 Rice tungro bacilliform virus P46 protein Troponin PF00992.15 EAQ88478.1 - 9.6 6.2 50.0 4.5 7.3 8.0 5.4 1 1 3 4 4 4 0 Troponin GFA PF04828.9 EAQ88481.1 - 9.8e-07 28.6 3.7 9.8e-07 28.6 2.5 2.2 3 0 0 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 EAQ88481.1 - 0.092 12.4 0.2 0.092 12.4 0.1 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ASFV_J13L PF05568.6 EAQ88482.1 - 0.0027 17.2 0.1 0.0042 16.6 0.1 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF1183 PF06682.7 EAQ88482.1 - 0.0033 17.0 0.0 0.0037 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2668 PF10873.3 EAQ88482.1 - 0.0036 17.4 0.1 0.0064 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) DUF4448 PF14610.1 EAQ88482.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.1 EAQ88482.1 - 0.013 15.7 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ni_hydr_CYTB PF01292.15 EAQ88482.1 - 0.069 12.5 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TMEM154 PF15102.1 EAQ88482.1 - 0.075 12.7 0.2 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 TMEM154 protein family PepSY_TM_2 PF13703.1 EAQ88482.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Herpes_gE PF02480.11 EAQ88482.1 - 0.17 10.1 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_M20 PF01546.23 EAQ88483.1 - 1.2e-23 83.5 0.0 1.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAQ88483.1 - 3.9e-14 52.3 0.1 1e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EAQ88483.1 - 3.2e-05 23.7 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Abhydrolase_3 PF07859.8 EAQ88486.1 - 3.6e-30 105.1 0.0 1.6e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ88486.1 - 4.6e-06 26.6 0.9 6.5e-06 26.1 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88486.1 - 5.6e-06 26.1 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAQ88486.1 - 5.3e-05 22.1 0.0 0.00021 20.1 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 EAQ88486.1 - 7.7e-05 21.3 0.0 0.00017 20.1 0.0 1.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EAQ88486.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.15 EAQ88486.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Glyco_hydro_31 PF01055.21 EAQ88487.1 - 3.2e-92 309.6 6.2 4.8e-92 309.1 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Clr5 PF14420.1 EAQ88488.1 - 2.4e-20 72.1 1.0 6.3e-20 70.8 0.7 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 EAQ88488.1 - 0.096 12.6 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 EAQ88490.1 - 2.8e-18 66.1 0.0 4.1e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ88490.1 - 1.6e-09 38.1 0.0 2.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88490.1 - 2.5e-07 30.4 0.0 3.8e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88490.1 - 2.8e-07 31.1 0.0 3.7e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ88490.1 - 7e-06 26.4 0.0 2.6e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ88490.1 - 9e-05 22.7 0.0 0.00026 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ88490.1 - 0.0015 17.7 0.0 0.019 14.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EAQ88490.1 - 0.024 14.6 0.6 0.18 11.8 0.0 2.2 2 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EAQ88490.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EAQ88490.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EAQ88490.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EAQ88490.1 - 0.099 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NmrA PF05368.8 EAQ88491.1 - 1.3e-12 47.5 0.1 4e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ88491.1 - 5.4e-05 23.2 0.3 0.00039 20.4 0.2 2.4 2 1 0 2 2 2 1 NADH(P)-binding Aldo_ket_red PF00248.16 EAQ88492.1 - 7e-57 192.3 0.0 8.1e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 EAQ88493.1 - 9.1e-22 76.8 0.0 1.8e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ88493.1 - 7e-18 64.1 0.0 2.1e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EAQ88493.1 - 0.00035 20.8 0.0 0.08 13.1 0.0 2.6 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ88493.1 - 0.021 15.2 0.0 0.098 13.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase AMP-binding PF00501.23 EAQ88494.1 - 8.8e-82 274.7 0.3 2.9e-80 269.7 0.2 2.3 1 1 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 EAQ88494.1 - 1.7e-63 214.9 0.0 2.9e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EAQ88494.1 - 6.7e-63 212.5 0.0 1.4e-62 211.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ88494.1 - 4.6e-61 205.6 3.3 1.4e-60 204.0 2.3 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAQ88494.1 - 1.6e-54 184.3 5.5 1.3e-53 181.3 2.4 3.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EAQ88494.1 - 2.5e-28 98.6 0.0 4.8e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EAQ88494.1 - 2.7e-16 59.5 0.3 2.7e-16 59.5 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain AMP-binding_C PF13193.1 EAQ88494.1 - 6.5e-09 36.6 0.9 3.2e-08 34.3 0.4 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EAQ88494.1 - 0.00059 18.8 0.2 0.0011 17.9 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.8 EAQ88494.1 - 0.028 13.6 0.1 0.052 12.7 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NmrA PF05368.8 EAQ88495.1 - 2.4e-16 59.6 0.0 9.9e-13 47.8 0.0 2.2 1 1 1 2 2 2 2 NmrA-like family KR PF08659.5 EAQ88495.1 - 2.1e-07 30.7 1.1 4.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EAQ88495.1 - 2.4e-06 27.5 1.1 1.5e-05 25.0 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAQ88495.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding AATase PF07247.7 EAQ88495.1 - 0.0078 14.8 0.0 0.014 13.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol acetyltransferase F420_oxidored PF03807.12 EAQ88495.1 - 0.053 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EAQ88495.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EAQ88495.1 - 0.31 9.6 0.1 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PhyH PF05721.8 EAQ88496.1 - 3.7e-35 121.8 0.0 7.2e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mem_trans PF03547.13 EAQ88496.1 - 1.3e-06 26.9 0.0 2.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Membrane transport protein DUF1479 PF07350.7 EAQ88496.1 - 0.14 10.6 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) NAD_binding_10 PF13460.1 EAQ88497.1 - 1.9e-11 44.3 0.0 2.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ88497.1 - 2.2e-07 30.3 0.0 3.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EAQ88497.1 - 0.023 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ88497.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4117 PF13491.1 EAQ88500.1 - 4.5 6.6 10.1 0.22 10.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4117) Abhydrolase_1 PF00561.15 EAQ88501.1 - 2.1e-14 53.6 0.0 3.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ88501.1 - 6.3e-14 52.4 0.0 1.5e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88501.1 - 2.4e-05 24.1 0.1 5.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EAQ88501.1 - 4.9e-05 21.9 0.0 7.5e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ank PF00023.25 EAQ88507.1 - 7.1e-15 53.9 0.5 0.00022 20.8 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 EAQ88507.1 - 1.4e-14 54.1 0.0 6.5e-06 26.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAQ88507.1 - 1.5e-10 40.2 3.4 0.002 18.1 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 EAQ88507.1 - 1.1e-08 35.3 1.2 0.22 12.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ88507.1 - 4.9e-07 29.7 1.5 0.027 14.7 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.2 EAQ88507.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like Fip1 PF05182.8 EAQ88508.1 - 2.1e-22 78.1 0.9 3.6e-22 77.3 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.1 EAQ88509.1 - 2.6e-11 43.7 60.3 9e-07 29.1 16.8 3.1 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF3584 PF12128.3 EAQ88509.1 - 0.068 10.5 0.2 0.12 9.7 0.1 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1192 PF06698.6 EAQ88509.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Med4 PF10018.4 EAQ88509.1 - 0.12 11.7 0.7 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 EURL PF06937.6 EAQ88509.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 EURL protein RNA_pol_3_Rpc31 PF11705.3 EAQ88510.1 - 1.5e-29 103.6 21.1 4.1e-29 102.1 14.6 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sec7 PF01369.15 EAQ88512.1 - 1.5e-63 213.8 0.5 1.5e-63 213.8 0.3 3.0 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.5 EAQ88512.1 - 5.3e-34 115.6 3.5 4.1e-32 109.5 0.2 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) Sec7_N PF12783.2 EAQ88512.1 - 6.5e-17 61.4 4.9 8.1e-17 61.1 0.0 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd1 PF12717.2 EAQ88512.1 - 0.023 14.5 0.3 6.1 6.6 0.0 3.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 2-oxoacid_dh PF00198.18 EAQ88513.1 - 4.4e-75 251.9 0.1 5.7e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EAQ88513.1 - 1.3e-18 66.3 0.9 3.5e-18 64.9 0.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EAQ88513.1 - 1.2e-09 37.5 0.7 4e-09 35.9 0.5 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 EAQ88513.1 - 0.0014 18.9 0.1 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3614) Zn_clus PF00172.13 EAQ88514.1 - 1.5e-08 34.3 11.6 5.3e-08 32.6 8.1 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ88514.1 - 0.00018 20.4 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_11 PF00457.12 EAQ88515.1 - 7.3e-78 260.1 20.8 8.6e-78 259.8 14.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Hepcidin PF06446.7 EAQ88516.1 - 0.14 12.5 3.4 0.27 11.6 2.3 1.6 1 0 0 1 1 1 0 Hepcidin DUF2367 PF10164.4 EAQ88518.1 - 0.0036 17.1 2.2 0.0041 16.9 0.4 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) GAS PF13851.1 EAQ88519.1 - 0.0003 20.0 15.6 0.00049 19.3 10.0 1.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 EAQ88519.1 - 0.00072 19.1 10.0 0.00072 19.1 6.9 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Clr2 PF10383.4 EAQ88519.1 - 0.098 12.6 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DUF3450 PF11932.3 EAQ88519.1 - 2.8 7.1 11.3 1.5 8.0 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 EAQ88519.1 - 4.7 7.0 16.9 0.15 11.8 2.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C4H2 PF10146.4 EAQ88519.1 - 7.1 6.5 15.4 1.5e+02 2.2 9.5 2.7 1 1 1 2 2 2 0 Zinc finger-containing protein CCDC155 PF14662.1 EAQ88519.1 - 7.6 6.0 23.1 18 4.8 16.0 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 zf-MYND PF01753.13 EAQ88520.1 - 0.0012 18.6 7.3 0.0012 18.6 5.0 2.2 2 0 0 2 2 2 1 MYND finger Ferritin_2 PF13668.1 EAQ88522.1 - 5.4e-17 62.0 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain p450 PF00067.17 EAQ88523.1 - 2.7e-50 171.2 0.0 1.2e-49 169.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Mannosyl_trans3 PF11051.3 EAQ88525.1 - 7.2e-74 248.5 0.0 2.1e-73 246.9 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative adh_short PF00106.20 EAQ88527.1 - 4e-06 26.8 0.0 6.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ88527.1 - 0.00046 19.8 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.21 EAQ88528.1 - 1.3e-56 191.9 4.2 1.5e-56 191.7 0.2 2.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ88528.1 - 1.9e-55 187.3 0.3 8.9e-55 185.1 0.2 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EAQ88528.1 - 1.2e-53 182.1 0.2 2.2e-53 181.3 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EAQ88528.1 - 5.5e-53 180.3 0.1 1e-52 179.4 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EAQ88528.1 - 1.3e-43 148.8 1.8 5.3e-43 146.8 0.1 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ88528.1 - 7e-41 138.8 0.1 2e-40 137.3 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EAQ88528.1 - 9.2e-16 58.8 0.1 3.7e-15 56.9 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EAQ88528.1 - 4.1e-11 42.5 0.9 5.4e-10 38.9 0.0 3.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EAQ88528.1 - 4.1e-06 26.9 0.2 1e-05 25.7 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EAQ88528.1 - 0.00085 18.3 0.1 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Saccharop_dh PF03435.13 EAQ88528.1 - 0.0027 16.7 0.1 0.0059 15.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase PCMT PF01135.14 EAQ88528.1 - 0.004 16.7 1.0 1.4 8.4 0.0 3.0 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EAQ88528.1 - 0.0077 16.6 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EAQ88528.1 - 0.0094 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein dTMP_synthase PF02593.9 EAQ88528.1 - 0.027 13.8 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate synthase Shikimate_DH PF01488.15 EAQ88528.1 - 0.029 14.4 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EAQ88528.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.1 EAQ88528.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EAQ88528.1 - 0.043 13.2 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ88528.1 - 0.14 10.7 0.1 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3632 PF12311.3 EAQ88530.1 - 3.1e-17 62.9 0.9 4.7e-17 62.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF3632 PF12311.3 EAQ88531.1 - 4.9e-30 104.7 0.1 6.1e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Cupin_2 PF07883.6 EAQ88532.1 - 5.2e-10 38.6 0.2 1.2e-09 37.5 0.1 1.6 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EAQ88532.1 - 7.7e-05 22.1 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.2 EAQ88532.1 - 0.0057 16.4 0.0 0.0087 15.8 0.0 1.4 1 1 0 1 1 1 1 ChrR Cupin-like domain Pirin PF02678.11 EAQ88532.1 - 0.026 14.3 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Pirin Fungal_trans PF04082.13 EAQ88533.1 - 8.9e-20 70.6 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88533.1 - 2.7e-09 36.8 9.3 5.9e-09 35.6 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4113 PF13438.1 EAQ88535.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Glyco_hydro_18 PF00704.23 EAQ88536.1 - 8.1e-29 101.1 1.4 9.6e-29 100.8 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-C2HC5 PF06221.8 EAQ88538.1 - 9.3e-22 76.5 4.1 1.4e-21 75.9 2.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SIR2 PF02146.12 EAQ88539.1 - 7.3e-31 107.2 0.0 3.4e-09 36.6 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Glyco_hydro_43 PF04616.9 EAQ88541.1 - 5.1e-16 58.6 2.7 7.9e-16 57.9 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pro-kuma_activ PF09286.6 EAQ88543.1 - 3.6e-29 101.6 0.0 7.2e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Na_H_Exchanger PF00999.16 EAQ88544.1 - 4.9e-20 71.3 48.1 1.3e-18 66.6 22.7 4.4 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family DUF2457 PF10446.4 EAQ88546.1 - 0.03 13.0 1.2 0.037 12.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PV-1 PF06637.6 EAQ88546.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) RVT_1 PF00078.22 EAQ88547.1 - 2.1e-30 105.6 0.0 2.9e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.1 EAQ88548.1 - 1.3e-20 73.6 0.0 2.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAQ88548.1 - 4.5e-10 39.5 0.0 4e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EAQ88548.1 - 0.00013 21.5 0.0 0.0017 17.9 0.0 2.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EAQ88548.1 - 0.00079 19.5 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EAQ88548.1 - 0.057 13.5 0.0 8.7 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF4442 PF14539.1 EAQ88548.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Sugarporin_N PF11471.3 EAQ88549.1 - 0.23 11.1 1.9 0.42 10.2 1.3 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Mito_fiss_reg PF05308.6 EAQ88549.1 - 9.6 5.4 8.5 21 4.3 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator PLAC8 PF04749.12 EAQ88550.1 - 2.1e-21 76.4 16.6 2.6e-21 76.1 11.5 1.1 1 0 0 1 1 1 1 PLAC8 family Humanin PF15040.1 EAQ88550.1 - 0.098 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Humanin family Lactamase_B_2 PF12706.2 EAQ88551.1 - 3.8e-21 75.5 0.0 5.3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAQ88551.1 - 6e-12 45.5 0.1 1.4e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAQ88551.1 - 0.0062 16.2 5.1 0.19 11.3 2.2 3.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_hydro_61 PF03443.9 EAQ88552.1 - 1.2e-44 152.7 0.1 1.4e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alk_phosphatase PF00245.15 EAQ88552.1 - 0.083 11.5 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Ldh_1_N PF00056.18 EAQ88553.1 - 2.6e-44 150.4 0.0 4.4e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EAQ88553.1 - 2.4e-41 141.3 0.0 3.6e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EAQ88553.1 - 8.5e-05 21.3 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EAQ88553.1 - 0.044 14.0 0.4 0.27 11.5 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 EAQ88553.1 - 0.05 12.9 0.1 3.5 6.8 0.2 2.4 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Hydrolase PF00702.21 EAQ88554.1 - 2.8e-23 83.4 0.0 1.8e-22 80.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAQ88554.1 - 7.2e-20 71.9 0.0 1.8e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAQ88554.1 - 1.8e-18 66.4 0.0 7.6e-18 64.3 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EAQ88554.1 - 5.3e-05 23.0 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAQ88554.1 - 0.002 17.7 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EAQ88554.1 - 0.042 13.1 0.1 1.8 7.8 0.0 2.9 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Whi5 PF08528.6 EAQ88555.1 - 2.2e-08 33.4 0.0 3.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Whi5 like AA_permease_2 PF13520.1 EAQ88556.1 - 5.8e-77 259.0 29.8 7.3e-77 258.6 20.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAQ88556.1 - 3.1e-14 52.2 25.1 1.9e-13 49.5 17.4 2.0 1 1 0 1 1 1 1 Amino acid permease V-SNARE_C PF12352.3 EAQ88557.1 - 4e-15 55.6 0.4 8.4e-15 54.5 0.3 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EAQ88557.1 - 0.00095 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 EAQ88557.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TPK_B1_binding PF04265.9 EAQ88558.1 - 2.6e-25 87.9 0.1 4.2e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 EAQ88558.1 - 5.2e-20 71.2 0.0 1.7e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF605 PF04652.11 EAQ88559.1 - 0.33 10.3 19.9 0.5 9.7 13.8 1.4 1 0 0 1 1 1 0 Vta1 like CHCH PF06747.8 EAQ88560.1 - 2.8e-05 23.8 0.4 5.3e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 CHCH domain DUF1068 PF06364.7 EAQ88560.1 - 0.052 13.1 0.7 0.081 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Herpes_UL56 PF04534.7 EAQ88561.1 - 0.00072 19.3 3.0 0.00082 19.1 2.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL56 protein DUF1764 PF08576.5 EAQ88561.1 - 0.13 13.0 1.4 0.23 12.2 0.9 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Spc7_N PF15402.1 EAQ88561.1 - 0.31 9.0 9.5 0.39 8.6 6.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RR_TM4-6 PF06459.7 EAQ88561.1 - 4.2 7.1 6.7 5.4 6.8 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fungal_trans_2 PF11951.3 EAQ88562.1 - 1.9e-05 23.4 0.0 4.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain IL22 PF14565.1 EAQ88563.1 - 0.31 11.1 3.9 0.36 10.8 0.5 2.2 1 1 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF883 PF05957.8 EAQ88563.1 - 0.54 10.6 4.5 0.44 10.9 1.8 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 EAQ88563.1 - 0.56 7.6 6.8 0.65 7.4 4.7 1.0 1 0 0 1 1 1 0 Prominin Spore_III_AF PF09581.5 EAQ88563.1 - 2 8.2 10.7 2.4 8.0 7.4 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ank_2 PF12796.2 EAQ88564.1 - 1.7e-11 44.2 0.0 4.5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ88564.1 - 3.8e-11 42.2 0.2 1.9e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EAQ88564.1 - 9.4e-09 34.6 0.0 0.00011 22.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EAQ88564.1 - 1.5e-06 28.2 0.3 0.00088 19.4 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ88564.1 - 0.00043 20.7 0.1 0.0061 17.0 0.0 2.5 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Spherulin4 PF12138.3 EAQ88564.1 - 0.031 13.7 0.0 0.15 11.4 0.0 1.7 2 1 0 2 2 2 0 Spherulation-specific family 4 AAA_22 PF13401.1 EAQ88564.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 EAQ88566.1 - 5.3e-05 22.3 0.0 7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase HA PF03457.9 EAQ88566.1 - 0.0053 16.8 0.1 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain zf-RVT PF13966.1 EAQ88569.1 - 0.047 13.9 0.1 0.089 13.1 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Myb_DNA-bind_3 PF12776.2 EAQ88570.1 - 3.6e-21 75.5 0.3 3.6e-21 75.5 0.2 2.4 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Suf PF05843.9 EAQ88570.1 - 0.0064 16.2 16.7 0.012 15.3 11.6 1.5 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 EAQ88570.1 - 0.063 12.6 12.0 0.11 11.8 8.3 1.3 1 0 0 1 1 1 0 Spt20 family SAGA-Tad1 PF12767.2 EAQ88570.1 - 0.71 9.4 14.8 1.3 8.5 10.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FimP PF09766.4 EAQ88570.1 - 1.2 8.1 15.3 2 7.3 10.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF4175 PF13779.1 EAQ88570.1 - 2.2 5.8 25.4 3.6 5.1 17.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LIM_bind PF01803.11 EAQ88570.1 - 4 6.4 12.4 6.9 5.7 8.6 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Tim54 PF11711.3 EAQ88570.1 - 9.3 4.7 11.0 19 3.7 7.5 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Asp PF00026.18 EAQ88571.1 - 1.3e-40 139.5 0.5 1.6e-40 139.3 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ88571.1 - 5.8e-05 23.1 0.0 9.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ88571.1 - 0.11 12.9 0.4 0.5 10.9 0.3 2.0 1 1 0 1 1 1 0 Aspartyl protease NACHT PF05729.7 EAQ88572.1 - 4.9e-05 23.0 0.0 0.00031 20.4 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 EAQ88572.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3 PF00933.16 EAQ88573.1 - 5.1e-87 291.6 0.0 8.5e-87 290.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ88573.1 - 3.2e-57 193.6 0.4 5.9e-57 192.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ88573.1 - 2.4e-25 88.2 0.0 5.2e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase PF00069.20 EAQ88575.1 - 1e-15 57.6 0.0 2.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88575.1 - 9.1e-12 44.5 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 EAQ88575.1 - 0.0035 16.4 15.1 0.14 11.2 0.3 3.1 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein VWA_2 PF13519.1 EAQ88575.1 - 0.13 12.3 0.0 0.57 10.2 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Nup54 PF13874.1 EAQ88575.1 - 0.18 11.4 1.9 0.52 9.9 1.3 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 COesterase PF00135.23 EAQ88576.1 - 1.5e-93 314.3 0.0 2.4e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ88576.1 - 3.7e-07 29.9 0.1 1.6e-06 27.8 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold IIGP PF05049.8 EAQ88576.1 - 1.7e-06 27.1 0.0 2.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Peptidase_S9 PF00326.16 EAQ88576.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family UvrD_C_2 PF13538.1 EAQ88576.1 - 0.012 15.7 0.0 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Abhydrolase_5 PF12695.2 EAQ88576.1 - 0.023 14.4 0.1 0.17 11.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Herpes_Helicase PF02689.9 EAQ88576.1 - 0.37 8.4 0.0 0.53 7.9 0.0 1.1 1 0 0 1 1 1 0 Helicase Chromo PF00385.19 EAQ88577.1 - 9.4e-14 50.8 0.6 2.2e-13 49.6 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Gly_transf_sug PF04488.10 EAQ88577.1 - 1.2e-05 25.5 0.0 2.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EAQ88577.1 - 0.068 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Tannase PF07519.6 EAQ88578.1 - 6.3e-87 292.2 0.0 7.2e-87 292.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EAQ88578.1 - 8.1e-06 25.8 0.0 6.3e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ88578.1 - 1.9e-05 23.9 0.1 0.12 11.6 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 EAQ88578.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 EAQ88578.1 - 0.017 14.8 0.1 0.51 10.0 0.1 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ88578.1 - 0.024 14.1 0.1 0.049 13.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold NADH-G_4Fe-4S_3 PF10588.4 EAQ88579.1 - 0.43 9.8 2.3 0.41 9.9 0.2 2.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn_clus PF00172.13 EAQ88580.1 - 1.4e-05 24.8 8.3 4.5e-05 23.2 5.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EAQ88582.1 - 2.9e-58 197.2 0.0 4.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ88582.1 - 4.5e-45 153.9 0.1 6.6e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ88582.1 - 6.4e-08 32.4 0.0 1.6e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Endonuclease_1 PF04231.8 EAQ88583.1 - 0.0077 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease I Rad17 PF03215.10 EAQ88583.1 - 0.15 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SR-25 PF10500.4 EAQ88583.1 - 0.64 9.4 7.8 1.1 8.7 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 EAQ88583.1 - 0.99 9.4 4.4 2.3 8.2 3.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aminotran_5 PF00266.14 EAQ88584.1 - 1.4e-15 56.9 0.0 5.4e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V RhoGAP PF00620.22 EAQ88585.1 - 3e-14 52.8 0.0 5.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Epimerase PF01370.16 EAQ88586.1 - 1.7e-17 63.6 0.8 2.7e-12 46.6 0.1 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ88586.1 - 3.4e-08 32.7 0.0 0.002 17.0 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EAQ88586.1 - 3.9e-06 25.7 0.0 0.00028 19.6 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EAQ88586.1 - 0.0014 18.6 0.0 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EAQ88586.1 - 0.045 13.6 0.1 2.8 7.8 0.1 2.5 1 1 1 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 EAQ88586.1 - 0.13 11.5 0.2 0.33 10.1 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family FAD_binding_3 PF01494.14 EAQ88587.1 - 1.2e-16 60.7 3.5 2.3e-08 33.5 0.3 3.4 4 0 0 4 4 4 3 FAD binding domain DAO PF01266.19 EAQ88587.1 - 9.1e-05 21.5 0.0 0.0002 20.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ88587.1 - 0.00094 19.5 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ88587.1 - 0.023 14.7 0.7 0.056 13.4 0.5 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PBD PF00786.23 EAQ88587.1 - 0.097 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 P21-Rho-binding domain F-box-like PF12937.2 EAQ88589.1 - 0.00065 19.3 0.1 0.0016 18.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ88589.1 - 0.00087 18.8 1.2 0.0033 17.0 0.1 2.4 2 0 0 2 2 2 1 F-box domain EBP PF05241.7 EAQ88590.1 - 2.2e-63 212.8 9.8 2.6e-63 212.5 6.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein His_Phos_2 PF00328.17 EAQ88592.1 - 1.9e-13 50.5 0.1 3e-12 46.5 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltransf_23 PF13489.1 EAQ88593.1 - 1.1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF928 PF06051.7 EAQ88593.1 - 0.11 12.0 0.5 0.17 11.4 0.2 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) Collagen PF01391.13 EAQ88594.1 - 0.00067 19.1 7.0 0.00097 18.6 4.9 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 EAQ88597.1 - 3.1e-34 118.2 9.1 3.1e-34 118.2 6.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UvrD_C_2 PF13538.1 EAQ88598.1 - 1.5e-05 25.0 0.0 0.00011 22.3 0.0 2.3 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ88598.1 - 0.028 14.5 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 Helicase associated domain FAD_binding_4 PF01565.18 EAQ88599.1 - 4.6e-21 74.7 2.5 4.8e-21 74.6 0.8 1.8 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EAQ88599.1 - 8.2e-11 41.6 0.1 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like VKOR PF07884.9 EAQ88600.1 - 4.4 7.1 10.5 1.3 8.8 1.9 2.5 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Trypan_PARP PF05887.6 EAQ88601.1 - 0.00024 20.9 128.0 0.00028 20.6 12.1 4.3 1 1 3 4 4 4 3 Procyclic acidic repetitive protein (PARP) BTB PF00651.26 EAQ88601.1 - 0.25 11.3 0.0 0.52 10.3 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain TPR_11 PF13414.1 EAQ88604.1 - 1.8e-06 27.4 4.4 5.5e-05 22.7 0.1 3.7 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 EAQ88604.1 - 0.00018 20.9 1.1 0.0016 17.9 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88604.1 - 0.001 18.9 0.7 0.1 12.5 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ88604.1 - 0.0013 18.3 0.7 0.032 14.0 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ88604.1 - 0.006 17.1 0.1 0.006 17.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88604.1 - 0.0094 15.7 6.5 0.0098 15.7 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ88604.1 - 0.078 13.6 0.5 0.078 13.6 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GYF PF02213.11 EAQ88605.1 - 1e-18 66.6 0.1 2.1e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 GYF domain SnoaL PF07366.7 EAQ88606.1 - 5.6e-05 22.7 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Virul_fac_BrkB PF03631.10 EAQ88607.1 - 0.046 13.0 4.7 0.075 12.3 3.2 1.3 1 0 0 1 1 1 0 Virulence factor BrkB 5_nucleotid_C PF02872.13 EAQ88608.1 - 5.7e-36 123.8 0.0 9.3e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EAQ88608.1 - 9.3e-08 31.7 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAQ88608.1 - 0.0043 16.9 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_1 PF00583.19 EAQ88609.1 - 5e-13 48.8 0.1 8.7e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAQ88609.1 - 7.1e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EAQ88609.1 - 1.5e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAQ88609.1 - 0.00028 20.9 0.0 0.0004 20.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAQ88609.1 - 0.032 14.4 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 EAQ88610.1 - 3e-10 39.7 3.8 6.7e-10 38.6 2.6 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ88610.1 - 7.5e-10 38.8 3.2 1.5e-09 37.9 2.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like APH PF01636.18 EAQ88610.1 - 4.4 6.9 8.4 5.2 6.7 1.4 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_4 PF13637.1 EAQ88611.1 - 1.6e-17 63.4 1.9 3.5e-09 36.9 0.0 4.6 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ88611.1 - 1.6e-15 57.2 0.0 2.9e-06 27.5 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ88611.1 - 8.4e-14 50.5 0.9 7.3e-06 25.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EAQ88611.1 - 1.3e-13 50.7 0.1 6e-05 23.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ88611.1 - 1.7e-12 46.2 0.3 0.00028 20.8 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EAQ88611.1 - 6.8e-06 25.6 0.2 7.6e-05 22.3 0.2 2.7 1 1 0 1 1 1 1 KilA-N domain Reo_sigmaC PF04582.7 EAQ88611.1 - 0.019 14.1 2.1 0.042 13.0 1.5 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3734 PF12536.3 EAQ88611.1 - 0.34 11.0 5.5 0.97 9.5 1.4 2.7 2 1 0 2 2 2 0 Patatin phospholipase COG2 PF06148.6 EAQ88611.1 - 0.79 9.5 6.1 0.93 9.3 2.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 EAQ88611.1 - 0.83 9.1 8.5 0.45 10.0 3.6 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NAD_binding_7 PF13241.1 EAQ88612.1 - 2.1e-33 114.6 0.0 2.8e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EAQ88612.1 - 1.4e-24 85.1 0.0 2.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EAQ88612.1 - 7.6e-15 53.5 0.2 1.2e-14 53.0 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 EAQ88612.1 - 0.0051 16.6 0.7 0.011 15.6 0.0 1.7 1 1 0 2 2 2 1 ThiF family Cas_GSU0053 PF09617.5 EAQ88612.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Shikimate_DH PF01488.15 EAQ88612.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FYVE PF01363.16 EAQ88613.1 - 6.3e-20 70.8 27.7 2.1e-15 56.3 6.3 2.9 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 EAQ88613.1 - 0.0029 17.4 2.6 0.0029 17.4 1.8 3.8 4 0 0 4 4 4 2 AN1-like Zinc finger Rbsn PF11464.3 EAQ88613.1 - 0.007 15.9 0.6 0.007 15.9 0.4 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-Di19 PF05605.7 EAQ88613.1 - 0.032 14.3 13.5 0.087 12.9 0.1 3.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC5 PF06221.8 EAQ88613.1 - 1.5 8.6 17.8 0.69 9.7 0.4 4.3 5 0 0 5 5 5 0 Putative zinc finger motif, C2HC5-type CENP-L PF13092.1 EAQ88614.1 - 2.5e-52 176.9 0.0 4e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 zf-C3HC4_2 PF13923.1 EAQ88615.1 - 0.0053 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ88615.1 - 0.025 14.3 0.8 0.045 13.4 0.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EAQ88615.1 - 0.032 14.0 0.6 0.069 13.0 0.1 1.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 EAQ88615.1 - 0.097 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EAQ88615.1 - 0.12 12.1 0.4 0.23 11.2 0.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EAQ88615.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_11 PF00457.12 EAQ88616.1 - 8.1e-77 256.7 23.1 9.9e-77 256.4 16.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 UDPG_MGDP_dh_N PF03721.9 EAQ88617.1 - 1.5e-45 154.8 0.1 7.6e-28 97.1 0.0 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EAQ88617.1 - 7.7e-30 102.9 0.0 1.4e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EAQ88617.1 - 8.9e-25 86.8 0.0 7.8e-20 71.0 0.0 3.5 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EAQ88617.1 - 1.7e-05 24.5 0.0 0.041 13.6 0.1 3.5 3 1 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EAQ88617.1 - 0.00064 18.7 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EAQ88617.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ88617.1 - 0.052 13.9 0.0 22 5.5 0.0 3.7 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_1 PF00534.15 EAQ88618.1 - 1.3e-32 112.6 0.0 1.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAQ88618.1 - 2.2e-13 50.5 0.0 4.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAQ88618.1 - 3.2e-12 46.8 0.8 1.2e-11 44.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EAQ88618.1 - 1.2e-10 41.4 0.0 2.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EAQ88618.1 - 1.8e-10 40.8 0.0 6.1e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 PRANC PF09372.5 EAQ88619.1 - 0.0022 17.8 0.3 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 PRANC domain Zwint PF15556.1 EAQ88619.1 - 0.014 14.6 1.8 0.017 14.4 1.2 1.2 1 0 0 1 1 1 0 ZW10 interactor DUF2072 PF09845.4 EAQ88619.1 - 0.1 12.5 1.0 0.13 12.1 0.4 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Mnd1 PF03962.10 EAQ88619.1 - 0.47 10.1 7.0 0.28 10.8 3.6 1.5 1 1 0 1 1 1 0 Mnd1 family RVT_1 PF00078.22 EAQ88620.1 - 3e-14 52.8 0.0 5.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIF1 PF05970.9 EAQ88621.1 - 6.2e-30 104.3 0.0 5.7e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EAQ88621.1 - 1.4e-05 23.0 0.0 0.0013 16.5 0.0 2.0 2 0 0 2 2 2 2 Helicase AAA_30 PF13604.1 EAQ88621.1 - 2.7e-05 23.8 0.0 6.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ88621.1 - 0.0002 21.0 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EAQ88621.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Torsin PF06309.6 EAQ88621.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.1 EAQ88621.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 EAQ88622.1 - 2.9e-30 104.4 5.5 1.4e-16 60.6 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ88622.1 - 1.2e-18 65.8 0.6 1.4e-08 34.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat HET PF06985.6 EAQ88622.1 - 5.4e-18 65.5 3.8 4.2e-14 52.8 0.4 3.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.1 EAQ88622.1 - 2.2e-12 47.1 0.2 6e-07 29.8 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ88622.1 - 9.2e-11 41.6 0.2 2.5e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ88622.1 - 1.1e-10 40.7 0.1 2.6e-06 27.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.17 EAQ88623.1 - 1.2e-57 195.4 0.0 3.8e-47 160.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Cutinase PF01083.17 EAQ88624.1 - 9.2e-51 172.0 10.3 1.1e-50 171.8 7.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EAQ88624.1 - 6e-06 25.8 0.1 8.3e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EAQ88624.1 - 5.3e-05 22.8 0.3 0.003 17.1 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ88624.1 - 0.018 14.9 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88624.1 - 0.083 12.6 0.8 0.12 12.0 0.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EAQ88624.1 - 0.091 11.9 0.2 0.27 10.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) DUF676 PF05057.9 EAQ88624.1 - 0.092 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) VirJ PF06057.6 EAQ88624.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_2 PF01674.13 EAQ88624.1 - 1 8.6 5.1 3 7.1 3.5 1.7 1 1 0 1 1 1 0 Lipase (class 2) DUF4360 PF14273.1 EAQ88625.1 - 1.8e-54 184.1 1.1 2.2e-54 183.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) ADP_ribosyl_GH PF03747.9 EAQ88626.1 - 6.2e-67 226.3 2.5 7.7e-67 226.0 1.7 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sulfate_transp PF00916.15 EAQ88627.1 - 1.6e-37 129.0 1.4 3.2e-37 128.0 0.3 1.8 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAQ88627.1 - 9.2e-27 92.5 3.0 9.2e-27 92.5 2.1 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EAQ88627.1 - 1.7e-15 56.4 0.0 3.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EAQ88627.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 STAS domain DUF3636 PF12331.3 EAQ88628.1 - 6.5e-52 175.0 0.0 1.2e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) CTP_transf_1 PF01148.15 EAQ88629.1 - 8.5e-79 264.8 28.0 1.1e-78 264.4 19.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 EAQ88630.1 - 1e-69 234.4 0.0 1.6e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAQ88630.1 - 6.3e-41 138.6 0.8 1.4e-40 137.5 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EAQ88630.1 - 0.029 14.3 0.1 0.083 12.9 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_cc PF11790.3 EAQ88631.1 - 1.6e-70 237.2 1.7 1.8e-70 237.0 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 EAQ88631.1 - 0.0088 15.7 0.2 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain MFS_1 PF07690.11 EAQ88632.1 - 4e-25 88.2 25.2 3.1e-24 85.3 12.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 EAQ88633.1 - 4.3e-105 350.8 0.7 7.4e-105 350.1 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GMC_oxred_N PF00732.14 EAQ88634.1 - 2.4e-35 122.1 0.2 1.8e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ88634.1 - 3.5e-12 46.8 0.0 6.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ88634.1 - 1.7e-08 33.7 1.7 2.5e-07 29.9 1.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ88634.1 - 8.3e-06 25.0 0.2 2.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EAQ88634.1 - 3.9e-05 23.5 0.7 9.7e-05 22.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ88634.1 - 0.00025 20.0 0.4 0.00047 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ88634.1 - 0.0013 18.6 0.6 0.059 13.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ88634.1 - 0.0014 18.6 0.4 0.012 15.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ88634.1 - 0.0046 15.4 0.1 0.069 11.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EAQ88634.1 - 0.0054 16.5 0.1 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DUF4473 PF14747.1 EAQ88634.1 - 0.024 14.8 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) FAD_binding_3 PF01494.14 EAQ88634.1 - 0.031 13.3 0.1 0.049 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EAQ88634.1 - 0.031 14.2 0.3 0.19 11.7 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 EAQ88634.1 - 0.043 12.7 0.1 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EAQ88634.1 - 0.11 12.9 0.4 0.95 9.9 0.3 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EAQ88635.1 - 8.8e-77 258.5 0.0 1.2e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EAQ88635.1 - 6.7e-34 117.2 0.0 1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EAQ88635.1 - 6.4e-23 81.3 0.0 1.6e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EAQ88635.1 - 1.3e-09 38.5 0.0 3.8e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EAQ88635.1 - 0.016 15.2 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EAQ88635.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like Peptidase_S10 PF00450.17 EAQ88636.1 - 1.3e-78 264.9 0.0 2.2e-78 264.2 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 EAQ88636.1 - 0.015 15.0 0.0 0.055 13.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 EAQ88637.1 - 4e-09 36.2 12.3 8.2e-09 35.2 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EAQ88638.1 - 8.4e-23 80.6 41.5 1.2e-22 80.0 28.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pox_A14 PF05767.7 EAQ88638.1 - 5.3 7.0 14.8 0.51 10.3 3.0 3.6 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 GMC_oxred_N PF00732.14 EAQ88639.1 - 7.2e-53 179.6 0.0 1.2e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ88639.1 - 8.6e-29 100.6 0.0 1.7e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ88639.1 - 5.3e-07 28.8 0.2 2.8e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ88639.1 - 1.4e-05 25.0 0.2 4.8e-05 23.3 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ88639.1 - 0.00045 19.2 0.4 0.00068 18.6 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Abhydrolase_5 PF12695.2 EAQ88639.1 - 0.00047 19.9 0.2 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ88639.1 - 0.001 18.3 0.7 0.0023 17.2 0.5 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family FAD_binding_2 PF00890.19 EAQ88639.1 - 0.0014 17.5 1.7 0.005 15.7 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain Esterase PF00756.15 EAQ88639.1 - 0.0065 15.9 0.1 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Pyr_redox_3 PF13738.1 EAQ88639.1 - 0.0081 16.2 3.1 0.6 10.1 1.1 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ88639.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EAQ88639.1 - 0.32 9.4 1.1 0.49 8.8 0.4 1.5 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_61 PF03443.9 EAQ88640.1 - 1e-17 64.7 0.0 1.4e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PIF1 PF05970.9 EAQ88641.1 - 3.1e-29 102.0 0.0 7.6e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase MULE PF10551.4 EAQ88641.1 - 1.8e-15 56.8 0.0 4.4e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain AAA_30 PF13604.1 EAQ88641.1 - 4.5e-06 26.3 0.0 7.3e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain FAR1 PF03101.10 EAQ88641.1 - 0.00017 22.0 0.2 0.00044 20.7 0.2 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain UvrD_C_2 PF13538.1 EAQ88641.1 - 0.00022 21.3 0.0 0.00082 19.4 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Transposase_mut PF00872.13 EAQ88641.1 - 0.00028 19.5 0.0 0.00052 18.6 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family AAA_19 PF13245.1 EAQ88641.1 - 0.00061 19.5 0.0 0.0022 17.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ88641.1 - 0.0011 16.8 0.0 0.0053 14.5 0.0 1.8 2 0 0 2 2 2 1 Helicase Torsin PF06309.6 EAQ88641.1 - 0.016 15.0 0.0 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Torsin DUF3505 PF12013.3 EAQ88642.1 - 5.1e-13 49.2 0.1 9.3e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DUF3505 PF12013.3 EAQ88643.1 - 5.4e-14 52.3 0.1 6.2e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-UBP PF02148.14 EAQ88643.1 - 0.077 13.1 1.7 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GspH PF12019.3 EAQ88644.1 - 2.6 8.2 22.6 1.5e+04 -14.7 15.7 7.3 1 1 0 1 1 1 0 Type II transport protein GspH PQQ_3 PF13570.1 EAQ88645.1 - 0.44 10.8 2.4 1.1e+02 3.3 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain Ctr PF04145.10 EAQ88646.1 - 1.2e-43 148.5 0.6 1.6e-43 148.2 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.5 EAQ88646.1 - 7.6 4.4 7.7 0.98 7.3 2.5 1.4 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DIT1_PvcA PF05141.7 EAQ88647.1 - 1.5e-91 306.5 0.0 2.2e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 EAQ88647.1 - 2.3e-60 204.4 0.0 3.5e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EAQ88648.1 - 2.1e-37 128.6 32.8 3.4e-37 127.9 22.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88648.1 - 1.4e-10 40.4 8.8 1.4e-10 40.4 6.1 2.3 2 1 0 3 3 3 1 Sugar (and other) transporter Metallophos PF00149.23 EAQ88650.1 - 5.7e-10 38.9 1.2 9.9e-10 38.1 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 EAQ88650.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.5 EAQ88650.1 - 0.0096 15.3 0.1 0.024 14.0 0.1 1.6 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Peptidase_M20 PF01546.23 EAQ88651.1 - 7.8e-05 22.2 0.5 0.00019 20.9 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Sugar_tr PF00083.19 EAQ88652.1 - 1.6e-80 270.9 19.7 1.8e-80 270.7 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ88652.1 - 7.4e-18 64.3 26.5 7.5e-17 61.0 12.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ88652.1 - 2e-06 26.4 16.9 9e-05 21.0 5.5 3.3 3 1 1 4 4 4 2 MFS/sugar transport protein Folate_carrier PF01770.13 EAQ88652.1 - 0.00059 18.4 3.1 0.0056 15.2 0.1 2.1 2 0 0 2 2 2 2 Reduced folate carrier Alpha-amylase PF00128.19 EAQ88653.1 - 1.7e-96 323.3 0.0 3.1e-96 322.4 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EAQ88653.1 - 0.0063 15.4 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Fungal_trans PF04082.13 EAQ88654.1 - 0.006 15.4 0.1 0.089 11.6 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain peroxidase PF00141.18 EAQ88655.1 - 1e-86 290.1 0.0 9.1e-45 152.9 0.0 2.3 2 0 0 2 2 2 2 Peroxidase ABC_membrane PF00664.18 EAQ88656.1 - 5.5e-76 255.5 27.9 4.9e-38 131.1 10.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ88656.1 - 2.5e-51 173.5 0.1 1.9e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EAQ88656.1 - 2.9e-09 36.3 0.4 0.00024 20.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAQ88656.1 - 9.5e-09 35.4 0.5 8.8e-05 22.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EAQ88656.1 - 2.2e-08 33.6 1.2 0.0098 15.1 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ88656.1 - 1.5e-07 31.6 0.0 0.68 9.8 0.0 3.3 3 0 0 3 3 3 3 AAA domain DUF258 PF03193.11 EAQ88656.1 - 2.3e-07 30.1 0.1 0.019 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EAQ88656.1 - 6.2e-07 28.7 0.6 0.0081 15.2 0.0 3.3 2 1 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EAQ88656.1 - 6.9e-07 28.8 1.3 0.15 11.4 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EAQ88656.1 - 1e-06 28.8 0.1 0.029 14.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAQ88656.1 - 1.1e-06 29.4 0.0 0.023 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAQ88656.1 - 0.00017 21.4 0.0 0.44 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EAQ88656.1 - 0.00038 19.1 1.5 0.068 11.7 0.2 3.2 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 EAQ88656.1 - 0.00053 19.5 1.6 1.9 7.8 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EAQ88656.1 - 0.0013 18.5 0.8 1.1 9.0 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_30 PF13604.1 EAQ88656.1 - 0.0015 18.1 2.8 1.7 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.15 EAQ88656.1 - 0.0027 16.4 0.0 0.78 8.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_19 PF13245.1 EAQ88656.1 - 0.0035 17.0 0.1 1.2 8.9 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EAQ88656.1 - 0.0039 17.4 0.0 3.4 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EAQ88656.1 - 0.004 16.6 0.0 1.2 8.5 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EAQ88656.1 - 0.0049 17.2 0.0 0.67 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ88656.1 - 0.0052 16.5 0.2 2.5 7.8 0.0 3.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 EAQ88656.1 - 0.016 14.8 0.1 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.13 EAQ88656.1 - 0.018 14.5 0.5 1.3 8.5 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EAQ88656.1 - 0.018 15.2 0.1 3.9 7.6 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EAQ88656.1 - 0.021 14.5 0.1 8.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAQ88656.1 - 0.037 14.5 1.3 19 5.7 0.0 3.7 5 0 0 5 5 3 0 Miro-like protein RelB_N PF12910.2 EAQ88656.1 - 0.038 13.3 0.4 1.1 8.7 0.3 2.4 1 1 1 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal AAA_14 PF13173.1 EAQ88656.1 - 0.051 13.4 0.0 13 5.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 EAQ88656.1 - 0.091 12.4 0.2 15 5.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 EAQ88656.1 - 0.096 11.7 0.0 7.2 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 EAQ88656.1 - 0.11 11.5 1.1 1.4 8.0 0.1 2.3 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.17 EAQ88656.1 - 0.12 12.5 0.3 11 6.1 0.0 2.9 3 0 0 3 3 2 0 RNA helicase DUF815 PF05673.8 EAQ88656.1 - 0.13 11.1 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.10 EAQ88656.1 - 0.29 9.7 0.0 0.65 8.5 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Fungal_trans PF04082.13 EAQ88657.1 - 1.6e-11 43.6 0.0 9e-11 41.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 EAQ88658.1 - 6.6e-24 84.6 0.0 9.5e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAQ88658.1 - 2e-08 33.2 0.0 3.8e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EAQ88658.1 - 0.00014 21.1 0.0 0.00027 20.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAQ88658.1 - 0.00018 21.5 0.3 0.00034 20.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88658.1 - 0.0021 17.8 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family CBM_10 PF02013.11 EAQ88659.1 - 0.17 12.2 0.8 0.17 12.2 0.6 1.8 2 0 0 2 2 2 0 Cellulose or protein binding domain FAD_binding_4 PF01565.18 EAQ88661.1 - 3.7e-13 49.1 0.8 8.4e-13 47.9 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ88661.1 - 2.3e-05 24.2 0.5 4.7e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EAQ88661.1 - 0.006 15.7 0.2 0.0096 15.0 0.2 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.17 EAQ88662.1 - 1.3e-27 96.4 0.0 1.7e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EAQ88664.1 - 5.7e-08 32.3 0.1 5.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ88664.1 - 0.00021 21.0 1.5 0.00047 19.8 1.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EAQ88665.1 - 1.1e-13 51.4 0.1 1.4e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ88665.1 - 3.6e-07 30.0 0.2 4.9e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ88665.1 - 0.00062 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 EAQ88666.1 - 4e-46 157.4 0.1 4.4e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_like PF09279.6 EAQ88666.1 - 0.037 14.0 0.2 0.45 10.5 0.2 2.7 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RhoGEF PF00621.15 EAQ88666.1 - 0.093 12.5 0.1 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 RhoGEF domain ketoacyl-synt PF00109.21 EAQ88667.1 - 7.4e-83 277.9 0.0 1.7e-82 276.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 EAQ88667.1 - 8.1e-73 245.1 0.0 1.4e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EAQ88667.1 - 2.1e-52 177.8 2.8 3.6e-52 177.0 1.9 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EAQ88667.1 - 3.5e-51 174.4 0.0 6.7e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAQ88667.1 - 4e-47 160.7 0.0 6.5e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EAQ88667.1 - 1.5e-41 142.0 0.1 1.2e-39 135.8 0.0 2.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EAQ88667.1 - 6.5e-40 136.6 0.0 3e-39 134.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EAQ88667.1 - 3.7e-34 118.0 0.1 1.2e-30 106.5 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ88667.1 - 7.9e-31 106.3 0.1 2e-30 105.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EAQ88667.1 - 1.7e-15 57.2 0.0 5.3e-15 55.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ88667.1 - 6.6e-15 55.1 2.0 3e-07 30.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EAQ88667.1 - 8.6e-15 54.8 0.0 3.2e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EAQ88667.1 - 1.4e-14 54.0 0.0 3.7e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ88667.1 - 1.1e-13 50.5 0.0 2.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HxxPF_rpt PF13745.1 EAQ88667.1 - 4e-11 43.0 0.0 1.1e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 EAQ88667.1 - 1.3e-10 41.6 0.0 5e-10 39.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88667.1 - 7.3e-09 35.3 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88667.1 - 3.1e-08 34.1 0.0 3.8e-07 30.6 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Thiolase_N PF00108.18 EAQ88667.1 - 2.4e-05 23.4 0.0 5.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EAQ88667.1 - 0.00039 19.5 0.0 0.00085 18.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EAQ88667.1 - 0.0017 17.8 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EAQ88667.1 - 0.0021 17.1 0.0 0.0048 15.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ACP_syn_III PF08545.5 EAQ88667.1 - 0.025 14.2 0.2 0.089 12.4 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_8 PF05148.10 EAQ88667.1 - 0.028 14.0 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase NodS PF05401.6 EAQ88667.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Abhydrolase_6 PF12697.2 EAQ88668.1 - 1.2e-07 31.8 0.5 2.4e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88668.1 - 0.00011 21.9 0.0 0.00061 19.5 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ88668.1 - 0.00047 19.4 0.1 0.00093 18.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.7 EAQ88668.1 - 0.22 11.2 0.0 0.54 9.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF3595 PF12166.3 EAQ88669.1 - 7.7 5.2 7.7 0.56 8.9 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) DUF2306 PF10067.4 EAQ88670.1 - 1.5e-10 41.0 6.1 1.5e-10 41.0 4.2 2.0 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) PrgI PF12666.2 EAQ88670.1 - 0.0042 17.1 0.3 0.0042 17.1 0.2 2.4 3 0 0 3 3 3 1 PrgI family protein Ferric_reduct PF01794.14 EAQ88670.1 - 4.3 7.4 9.3 10 6.2 6.4 1.8 1 1 0 1 1 1 0 Ferric reductase like transmembrane component DUF3592 PF12158.3 EAQ88670.1 - 9.7 5.9 7.0 0.81 9.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) adh_short PF00106.20 EAQ88671.1 - 9.2e-27 93.9 0.3 1.1e-26 93.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ88671.1 - 2.3e-09 37.1 0.1 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ88671.1 - 7.2e-09 35.7 0.0 9.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ88671.1 - 0.00091 18.7 0.2 0.0013 18.1 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ88671.1 - 0.0092 16.0 0.3 0.013 15.5 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EAQ88671.1 - 0.038 13.7 0.3 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EAQ88671.1 - 0.068 12.0 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain zf-CCHH PF10283.4 EAQ88672.1 - 4.1 7.3 8.8 8.5 6.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif RVT_1 PF00078.22 EAQ88673.1 - 3.7e-31 108.1 0.0 5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 EAQ88674.1 - 5.3e-34 117.5 0.0 8.5e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SurE PF01975.12 EAQ88675.1 - 1.2e-27 96.4 0.1 1.7e-27 95.9 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Fungal_lectin PF07938.7 EAQ88677.1 - 3.6e-12 46.2 0.8 1.8e-11 43.9 0.1 1.9 1 1 0 2 2 2 1 Fungal fucose-specific lectin Glycos_transf_1 PF00534.15 EAQ88678.1 - 1.2e-06 28.0 0.0 2.9e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAQ88678.1 - 4.5e-05 23.6 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAQ88678.1 - 0.0076 16.4 0.4 0.032 14.3 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain MFS_1 PF07690.11 EAQ88680.1 - 2.1e-08 33.3 28.7 3.1e-08 32.7 19.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4006 PF13179.1 EAQ88680.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Fungal_trans_2 PF11951.3 EAQ88681.1 - 7.7e-32 110.3 0.9 1e-31 109.9 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88681.1 - 3.5e-08 33.2 7.3 6.5e-08 32.3 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLIC PF05783.6 EAQ88682.1 - 0.49 9.0 2.7 0.82 8.2 1.8 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Thioredoxin PF00085.15 EAQ88683.1 - 1.2e-26 92.4 0.0 1.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EAQ88683.1 - 5.9e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EAQ88683.1 - 4.8e-06 26.7 0.2 0.00014 21.9 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EAQ88683.1 - 3.2e-05 23.8 0.1 7.6e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EAQ88683.1 - 0.00072 19.2 0.1 0.00097 18.8 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EAQ88683.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EAQ88683.1 - 0.034 13.6 0.1 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 Redoxin DIM1 PF02966.11 EAQ88683.1 - 0.05 13.1 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 SnoaL_4 PF13577.1 EAQ88684.1 - 4.2e-09 36.3 0.0 6.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain IncA PF04156.9 EAQ88686.1 - 2.1e-09 37.2 73.1 0.00068 19.2 1.0 6.7 2 1 4 6 6 6 5 IncA protein Myosin_tail_1 PF01576.14 EAQ88686.1 - 2.7e-08 32.0 20.9 2.7e-08 32.0 14.5 3.5 2 1 1 3 3 3 1 Myosin tail Filament PF00038.16 EAQ88686.1 - 2.1e-05 24.1 33.5 0.00032 20.2 16.1 4.3 1 1 3 4 4 3 3 Intermediate filament protein Med9 PF07544.8 EAQ88686.1 - 0.00043 19.9 1.6 0.00043 19.9 1.1 6.0 4 2 4 8 8 7 1 RNA polymerase II transcription mediator complex subunit 9 Macoilin PF09726.4 EAQ88686.1 - 0.00094 17.5 7.3 0.00094 17.5 5.1 5.2 2 2 1 4 4 2 1 Transmembrane protein FlxA PF14282.1 EAQ88686.1 - 0.0011 18.9 1.9 0.0011 18.9 1.3 7.6 4 2 3 7 7 5 2 FlxA-like protein ADIP PF11559.3 EAQ88686.1 - 0.0018 18.2 2.7 0.0018 18.2 1.9 7.3 3 2 3 8 8 8 1 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.5 EAQ88686.1 - 0.0026 17.7 4.6 0.0026 17.7 3.2 6.9 3 1 2 6 6 5 2 Cortexillin I, coiled coil APG6 PF04111.7 EAQ88686.1 - 0.0049 15.9 4.7 0.0049 15.9 3.2 5.3 2 1 3 5 5 5 3 Autophagy protein Apg6 DUF4140 PF13600.1 EAQ88686.1 - 0.031 14.7 1.3 0.031 14.7 0.9 9.5 3 3 4 7 7 6 0 N-terminal domain of unknown function (DUF4140) Reo_sigmaC PF04582.7 EAQ88686.1 - 0.033 13.3 47.9 0.017 14.3 4.2 5.0 3 1 1 5 5 4 0 Reovirus sigma C capsid protein Striatin PF08232.7 EAQ88686.1 - 0.083 13.2 70.7 0.095 13.0 0.9 7.6 3 2 3 6 6 5 0 Striatin family CENP-F_leu_zip PF10473.4 EAQ88686.1 - 0.18 11.6 91.4 0.042 13.7 4.0 7.5 2 2 4 6 6 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EAQ88686.1 - 1.4 7.4 72.1 0.016 13.9 6.2 5.2 2 1 3 6 6 6 0 Spc7 kinetochore protein CALCOCO1 PF07888.6 EAQ88686.1 - 8.3 4.5 78.2 0.43 8.8 1.9 5.5 2 1 2 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4582 PF15189.1 EAQ88690.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Cyclin PF08613.6 EAQ88691.1 - 3.5e-16 59.9 0.0 6.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EAQ88691.1 - 9.3e-06 25.2 0.1 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arrestin_C PF02752.17 EAQ88692.1 - 1.6e-16 60.6 0.0 7.4e-16 58.4 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EAQ88692.1 - 1.4e-06 28.2 6.9 0.0033 17.2 0.0 3.8 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Aldo_ket_red PF00248.16 EAQ88693.1 - 1.2e-62 211.3 0.0 1.9e-62 210.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EAQ88694.1 - 6.9e-27 93.3 4.8 1.1e-26 92.7 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ88694.1 - 2.5e-18 65.8 0.0 4.2e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ88694.1 - 0.0027 18.6 0.0 0.005 17.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EAQ88694.1 - 0.018 14.2 0.4 0.03 13.4 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PucR PF07905.6 EAQ88694.1 - 0.05 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Chs3p PF12271.3 EAQ88695.1 - 6.3e-140 465.2 13.4 7.1e-140 465.0 9.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3716 PF12511.3 EAQ88696.1 - 5.6e-12 45.0 6.1 1e-11 44.2 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Ribosomal_S6 PF01250.12 EAQ88696.1 - 1e-07 31.6 0.0 2.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.10 EAQ88697.1 - 7.6e-29 100.2 3.4 1.5e-28 99.3 2.3 1.5 1 0 0 1 1 1 1 Cullin binding PX PF00787.19 EAQ88699.1 - 2.5e-18 65.8 0.1 5e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 PX domain BTAD PF03704.12 EAQ88699.1 - 0.015 15.5 1.8 0.03 14.6 1.2 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Ribosomal_L18e PF00828.14 EAQ88700.1 - 4.1e-12 46.5 0.0 8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Methyltransf_23 PF13489.1 EAQ88703.1 - 3.3e-19 69.1 0.0 6.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88703.1 - 2.1e-09 37.1 0.0 3.4e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88703.1 - 6.9e-09 36.2 0.0 5.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ88703.1 - 9.4e-08 32.4 0.0 1.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ88703.1 - 5.9e-07 29.8 0.0 2.2e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ88703.1 - 7.9e-06 26.1 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ88703.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAQ88703.1 - 0.0003 19.8 0.0 0.00064 18.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EAQ88703.1 - 0.00034 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EAQ88703.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EAQ88703.1 - 0.0026 17.1 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EAQ88703.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EAQ88703.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SF3a60_bindingd PF12108.3 EAQ88703.1 - 0.047 13.2 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain NmrA PF05368.8 EAQ88704.1 - 2.9e-31 108.5 0.0 7.1e-31 107.2 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ88704.1 - 1e-10 41.9 0.1 1.4e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EAQ88704.1 - 0.00023 21.1 0.6 0.00052 19.9 0.4 1.6 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EAQ88704.1 - 0.00059 19.8 0.4 0.0014 18.5 0.0 1.8 3 0 0 3 3 3 1 TrkA-N domain 3Beta_HSD PF01073.14 EAQ88704.1 - 0.00065 18.4 0.0 0.00099 17.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EAQ88704.1 - 0.0036 17.0 0.3 0.0086 15.7 0.2 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ88704.1 - 0.0071 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EAQ88704.1 - 0.022 15.0 0.1 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ88704.1 - 0.13 12.7 0.1 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 EAQ88706.1 - 2.9e-52 177.7 0.1 1.8e-48 165.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Peptidase_S8 PF00082.17 EAQ88708.1 - 4.6e-15 55.5 0.0 8.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.1 EAQ88708.1 - 0.0021 18.4 1.3 7.3 7.2 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) DUF3829 PF12889.2 EAQ88708.1 - 0.0022 17.2 1.0 0.0022 17.2 0.7 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3829) Ank_2 PF12796.2 EAQ88708.1 - 0.0079 16.5 0.3 0.71 10.2 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) APG6 PF04111.7 EAQ88708.1 - 1.1 8.2 18.1 1.2 8.1 11.2 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Ank_2 PF12796.2 EAQ88709.1 - 6.2e-91 298.8 5.8 6e-16 58.5 0.0 11.1 4 4 8 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ88709.1 - 2.4e-72 235.3 38.1 6.6e-09 35.1 0.0 19.1 20 0 0 20 20 20 13 Ankyrin repeat Ank_4 PF13637.1 EAQ88709.1 - 1e-70 232.9 21.5 1.5e-09 38.1 0.0 14.4 8 4 9 17 17 17 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ88709.1 - 7e-59 194.5 26.5 2.6e-10 40.1 0.0 13.9 7 3 9 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ88709.1 - 8.2e-55 177.2 12.6 3.7e-06 26.6 0.0 19.0 19 1 1 20 20 20 12 Ankyrin repeat ZZ PF00569.12 EAQ88709.1 - 0.13 11.7 9.9 0.26 10.8 6.8 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type GIT_SHD PF08518.6 EAQ88710.1 - 0.0044 16.3 0.2 0.0044 16.3 0.2 2.5 3 0 0 3 3 3 1 Spa2 homology domain (SHD) of GIT Abhydrolase_5 PF12695.2 EAQ88711.1 - 2.7e-18 66.1 0.1 4e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ88711.1 - 4.9e-11 42.9 3.9 5.9e-09 36.1 2.3 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ88711.1 - 5.8e-08 32.5 0.0 8.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ88711.1 - 5.9e-05 22.3 0.2 0.0031 16.7 0.1 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EAQ88711.1 - 9e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EAQ88711.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase VirJ PF06057.6 EAQ88711.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.15 EAQ88711.1 - 0.054 13.7 0.2 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain PhoPQ_related PF10142.4 EAQ88711.1 - 0.12 10.7 0.1 0.53 8.7 0.1 1.8 1 1 1 2 2 2 0 PhoPQ-activated pathogenicity-related protein FAD_binding_3 PF01494.14 EAQ88712.1 - 2.6e-76 256.9 0.0 3.4e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EAQ88712.1 - 2.7e-27 95.4 0.4 3.4e-21 75.6 0.0 2.3 1 1 1 2 2 2 2 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EAQ88712.1 - 0.0011 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EAQ88712.1 - 0.0017 17.3 0.1 0.0093 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ88712.1 - 0.0032 16.3 0.1 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ88712.1 - 0.0068 16.4 0.1 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EAQ88712.1 - 0.0083 14.9 0.0 0.027 13.2 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.2 EAQ88712.1 - 0.019 14.0 0.1 0.025 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EAQ88712.1 - 0.03 13.9 0.2 0.071 12.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EAQ88712.1 - 0.03 13.3 0.1 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EAQ88712.1 - 0.065 13.0 0.2 0.21 11.4 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ88712.1 - 0.075 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HpcH_HpaI PF03328.9 EAQ88713.1 - 3.8e-48 163.2 0.0 5.4e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EAQ88713.1 - 0.0016 17.1 0.1 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HDPD PF02924.9 EAQ88713.1 - 0.014 15.2 2.4 0.032 14.0 0.3 2.1 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Chromo PF00385.19 EAQ88715.1 - 5.1e-13 48.4 0.1 1.1e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EAQ88715.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger APH PF01636.18 EAQ88716.1 - 1.1e-13 51.4 1.7 2e-12 47.3 1.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EAQ88716.1 - 0.0026 16.4 0.0 0.0033 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EAQ88716.1 - 0.0089 15.2 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase NAD_binding_10 PF13460.1 EAQ88718.1 - 4.8e-07 29.9 0.0 9.5e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ88718.1 - 0.0021 17.3 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAQ88718.1 - 0.029 14.3 0.5 0.043 13.7 0.3 1.5 1 1 0 1 1 1 0 short chain dehydrogenase SSP160 PF06933.6 EAQ88718.1 - 1.2 7.0 8.6 1.4 6.8 6.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Osmo_MPGsynth PF09488.5 EAQ88720.1 - 4.3e-113 377.8 0.0 5.3e-113 377.5 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) IucA_IucC PF04183.7 EAQ88722.1 - 3e-18 66.0 0.9 4.6e-15 55.5 0.1 2.2 1 1 1 2 2 2 2 IucA / IucC family FhuF PF06276.7 EAQ88722.1 - 3.9e-16 59.4 0.1 9.5e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Ferric iron reductase FhuF-like transporter MULE PF10551.4 EAQ88724.1 - 2.2e-13 50.1 0.3 2.1e-12 47.0 0.0 2.6 2 1 1 3 3 3 1 MULE transposase domain mTERF PF02536.9 EAQ88724.1 - 0.041 12.4 0.0 0.091 11.3 0.0 1.5 1 0 0 1 1 1 0 mTERF AIG2 PF06094.7 EAQ88726.1 - 1.7e-11 44.5 0.0 2.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EAQ88727.1 - 2.1e-11 44.2 0.1 2.9e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Amidoligase_2 PF12224.3 EAQ88728.1 - 7.9e-18 64.9 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Mito_fiss_reg PF05308.6 EAQ88728.1 - 0.53 9.6 7.6 0.89 8.8 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator NHL PF01436.16 EAQ88729.1 - 0.0031 17.3 2.4 0.28 11.2 0.1 3.3 4 0 0 4 4 4 2 NHL repeat DUF4394 PF14339.1 EAQ88729.1 - 0.0048 16.2 1.9 0.48 9.6 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4394) Ank_5 PF13857.1 EAQ88731.1 - 4.4e-15 55.3 0.2 6.7e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ88731.1 - 6.6e-14 52.0 0.1 1.7e-07 31.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ88731.1 - 1.3e-13 51.0 0.0 1.7e-07 31.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EAQ88731.1 - 1.5e-10 40.3 1.5 4.4e-06 26.2 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EAQ88731.1 - 1.4e-07 31.0 0.9 0.0019 18.2 0.0 3.9 5 0 0 5 5 5 2 Ankyrin repeat Macoilin PF09726.4 EAQ88731.1 - 8.3 4.5 6.2 12 3.9 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein GPI-anchored PF10342.4 EAQ88732.1 - 2e-18 66.6 0.8 2e-18 66.6 0.6 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIF_beta PF02270.10 EAQ88732.1 - 0.0086 15.9 0.1 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF4614 PF15391.1 EAQ88732.1 - 0.8 9.4 14.4 0.2 11.4 8.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Peptidase_S64 PF08192.6 EAQ88732.1 - 7.3 4.7 11.9 9.3 4.4 8.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_A_exo1 PF01612.15 EAQ88734.1 - 0.0037 16.7 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease DUF2235 PF09994.4 EAQ88736.1 - 1e-64 218.6 0.0 6.7e-64 215.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EAQ88736.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 EAQ88738.1 - 6.6e-39 133.4 0.0 3.2e-33 114.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family AMP-binding PF00501.23 EAQ88739.1 - 2.3e-83 279.9 0.5 4.3e-83 279.0 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EAQ88739.1 - 2.2e-70 237.0 0.0 4.3e-70 236.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ88739.1 - 1.8e-50 172.1 0.1 3.5e-50 171.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAQ88739.1 - 2e-48 165.0 1.6 5.6e-48 163.6 0.0 2.5 3 0 0 3 3 3 1 Polyketide synthase dehydratase KR PF08659.5 EAQ88739.1 - 7.7e-42 142.9 0.8 3e-41 141.0 0.0 2.3 2 0 0 2 2 2 1 KR domain Condensation PF00668.15 EAQ88739.1 - 5e-36 124.0 0.0 9.4e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EAQ88739.1 - 1.2e-33 116.4 1.5 2.9e-33 115.1 0.0 2.6 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ88739.1 - 1.6e-29 102.1 0.1 6.3e-29 100.2 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EAQ88739.1 - 7.5e-14 51.7 0.0 1.9e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EAQ88739.1 - 2.3e-13 50.4 0.0 5.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88739.1 - 6.2e-10 38.8 0.0 2.4e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ88739.1 - 1.4e-09 38.2 0.0 4.3e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88739.1 - 1.6e-09 38.2 0.0 2.8e-08 34.2 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ88739.1 - 4.2e-08 33.0 0.0 2.8e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 EAQ88739.1 - 1.3e-07 31.8 0.0 1.4e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 HxxPF-repeated domain Thiolase_N PF00108.18 EAQ88739.1 - 2.8e-06 26.5 0.1 5.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EAQ88739.1 - 0.011 14.8 0.0 0.035 13.2 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EAQ88739.1 - 0.018 15.4 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain DUF2000 PF09391.5 EAQ88739.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) CPSF_A PF03178.10 EAQ88740.1 - 6e-96 321.2 0.0 8.1e-95 317.5 0.0 2.5 2 1 1 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EAQ88740.1 - 2.8e-44 151.1 0.8 4.9e-44 150.3 0.5 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EAQ88740.1 - 0.007 16.2 0.3 0.056 13.3 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat CBM_10 PF02013.11 EAQ88741.1 - 0.18 12.0 2.0 0.35 11.1 1.4 1.4 1 0 0 1 1 1 0 Cellulose or protein binding domain 4HBT_3 PF13622.1 EAQ88742.1 - 0.0044 16.7 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily COX5B PF01215.14 EAQ88743.1 - 4.5e-41 139.6 0.0 5.6e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C2H2_3 PF13878.1 EAQ88743.1 - 0.18 11.3 1.5 0.3 10.6 1.1 1.3 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO DUF4604 PF15377.1 EAQ88744.1 - 8.3e-24 84.5 11.1 1.2e-23 84.0 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) FLO_LFY PF01698.11 EAQ88744.1 - 0.00085 18.2 3.4 0.0011 17.9 2.4 1.0 1 0 0 1 1 1 1 Floricaula / Leafy protein Ank_2 PF12796.2 EAQ88745.1 - 4e-24 84.7 0.4 5.8e-11 42.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ88745.1 - 5.1e-20 70.2 5.0 3.2e-07 29.8 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Clr5 PF14420.1 EAQ88745.1 - 2.3e-16 59.3 1.5 3.8e-16 58.7 1.0 1.3 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.1 EAQ88745.1 - 2.4e-14 53.0 0.8 4.7e-06 26.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ88745.1 - 1e-13 50.0 0.2 2.6e-05 24.0 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EAQ88745.1 - 4.1e-12 46.2 0.5 7.4e-05 23.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Glyco_hydro_16 PF00722.16 EAQ88748.1 - 6.6e-44 149.4 4.0 1e-43 148.7 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Myb_DNA-bind_6 PF13921.1 EAQ88750.1 - 0.0015 18.6 0.2 0.003 17.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Exonuc_VIII PF06630.6 EAQ88750.1 - 0.051 12.9 1.3 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII Myb_DNA-binding PF00249.26 EAQ88750.1 - 0.053 13.5 0.1 0.26 11.3 0.2 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain MULE PF10551.4 EAQ88751.1 - 1.2e-17 63.8 0.3 2.4e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 EAQ88751.1 - 9.1e-06 24.4 0.0 1.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family XkdW PF09636.5 EAQ88751.1 - 0.045 13.6 0.2 0.08 12.8 0.1 1.4 1 0 0 1 1 1 0 XkdW protein FCH PF00611.18 EAQ88751.1 - 0.072 13.2 0.3 0.64 10.2 0.0 2.4 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain RVT_1 PF00078.22 EAQ88752.1 - 1.1e-30 106.5 0.0 1.8e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ88752.1 - 4.2e-10 39.2 0.0 8.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ88752.1 - 2e-06 27.9 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PurS PF02700.9 EAQ88752.1 - 0.027 14.4 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase NACHT PF05729.7 EAQ88753.1 - 1.8e-06 27.7 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EAQ88753.1 - 1.9e-05 24.0 0.0 3.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EAQ88753.1 - 0.00041 20.0 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF829 PF05705.9 EAQ88753.1 - 0.0011 18.7 0.1 0.0075 15.9 0.0 2.3 3 0 0 3 3 3 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EAQ88753.1 - 0.0016 18.4 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EAQ88753.1 - 0.0076 16.3 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cutinase PF01083.17 EAQ88753.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase CASP_C PF08172.7 EAQ88754.1 - 2.8e-05 23.2 2.5 2.8e-05 23.2 1.8 1.3 2 0 0 2 2 1 1 CASP C terminal Fib_alpha PF08702.5 EAQ88754.1 - 0.003 17.6 3.1 0.003 17.6 1.4 1.5 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EAQ88754.1 - 0.0031 16.5 4.3 0.0033 16.4 3.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EAQ88754.1 - 0.0035 15.8 0.9 0.0041 15.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) APG6 PF04111.7 EAQ88754.1 - 0.0042 16.1 2.9 0.0044 16.1 2.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Filament PF00038.16 EAQ88754.1 - 0.0053 16.2 4.7 0.0069 15.9 3.2 1.4 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EAQ88754.1 - 0.0056 16.4 4.5 0.0091 15.7 3.1 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EAQ88754.1 - 0.0096 15.5 8.8 0.018 14.6 5.7 1.7 1 1 0 1 1 1 1 IncA protein Herpes_UL6 PF01763.11 EAQ88754.1 - 0.0096 14.1 1.5 0.01 14.0 1.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like Myosin_tail_1 PF01576.14 EAQ88754.1 - 0.011 13.4 7.3 0.016 12.9 5.1 1.2 1 0 0 1 1 1 0 Myosin tail SseC PF04888.7 EAQ88754.1 - 0.012 14.9 2.8 0.013 14.8 2.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ADIP PF11559.3 EAQ88754.1 - 0.023 14.5 9.0 0.039 13.8 6.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EAQ88754.1 - 0.026 14.0 5.6 0.042 13.3 3.9 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 EAQ88754.1 - 0.029 11.7 5.3 0.031 11.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EAQ88754.1 - 0.031 13.4 0.9 0.039 13.1 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein P4Ha_N PF08336.6 EAQ88754.1 - 0.038 13.8 1.4 0.064 13.0 1.0 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Baculo_PEP_C PF04513.7 EAQ88754.1 - 0.038 13.8 5.2 0.055 13.2 3.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 EAQ88754.1 - 0.046 13.5 6.5 0.025 14.3 3.0 1.7 2 1 0 2 2 1 0 LXG domain of WXG superfamily SlyX PF04102.7 EAQ88754.1 - 0.048 14.0 12.1 0.049 14.0 6.4 2.3 1 1 1 2 2 2 0 SlyX Spc7 PF08317.6 EAQ88754.1 - 0.056 12.0 4.6 0.08 11.5 3.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Rapamycin_bind PF08771.6 EAQ88754.1 - 0.057 13.5 0.8 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 Rapamycin binding domain ING PF12998.2 EAQ88754.1 - 0.058 13.6 5.6 0.091 13.0 3.9 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Mod_r PF07200.8 EAQ88754.1 - 0.06 13.2 5.8 0.12 12.2 4.1 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 EAQ88754.1 - 0.063 12.9 4.4 0.1 12.2 3.1 1.3 1 0 0 1 1 1 0 Mnd1 family Bacillus_HBL PF05791.6 EAQ88754.1 - 0.063 12.6 2.8 0.091 12.1 1.9 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.7 EAQ88754.1 - 0.066 12.9 3.2 0.13 12.0 2.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 EAQ88754.1 - 0.071 10.9 1.4 0.12 10.2 0.7 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 EAQ88754.1 - 0.085 10.3 1.1 0.11 10.0 0.8 1.2 1 0 0 1 1 1 0 Prominin DUF948 PF06103.6 EAQ88754.1 - 0.099 12.5 4.0 0.13 12.1 1.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SecA_DEAD PF07517.9 EAQ88754.1 - 0.13 11.5 5.2 0.53 9.5 3.6 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain Pepsin-I3 PF06394.8 EAQ88754.1 - 0.14 11.8 1.8 0.27 10.9 1.2 1.4 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Adenylsucc_synt PF00709.16 EAQ88754.1 - 0.14 10.7 1.5 0.17 10.5 1.0 1.0 1 0 0 1 1 1 0 Adenylosuccinate synthetase AAA_13 PF13166.1 EAQ88754.1 - 0.16 10.4 2.6 0.22 9.9 1.8 1.2 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.8 EAQ88754.1 - 0.16 12.3 11.2 0.46 10.9 3.0 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) NYD-SP28 PF14772.1 EAQ88754.1 - 0.19 11.8 6.5 0.54 10.3 4.5 1.7 1 1 0 1 1 1 0 Sperm tail FUSC PF04632.7 EAQ88754.1 - 0.21 9.9 7.0 0.27 9.6 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GP20 PF06810.6 EAQ88754.1 - 0.3 10.5 4.6 0.41 10.0 3.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 EAQ88754.1 - 0.3 10.8 8.4 0.62 9.8 5.6 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PilJ PF13675.1 EAQ88754.1 - 0.33 11.3 7.0 0.36 11.1 3.6 1.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Phage_GPO PF05929.6 EAQ88754.1 - 0.38 9.9 5.9 0.076 12.2 0.9 1.8 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_DNA_bd PF12329.3 EAQ88754.1 - 0.4 10.5 7.7 0.24 11.2 3.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 EAQ88754.1 - 0.41 10.3 5.9 1.2 8.9 2.6 2.1 2 0 0 2 2 2 0 Laminin Domain II Seryl_tRNA_N PF02403.17 EAQ88754.1 - 0.42 10.6 7.0 0.5 10.3 3.6 2.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain AATF-Che1 PF13339.1 EAQ88754.1 - 0.43 10.7 4.7 4.1 7.5 1.2 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF724 PF05266.9 EAQ88754.1 - 0.46 10.0 3.6 0.64 9.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.7 EAQ88754.1 - 0.51 9.6 9.7 0.9 8.8 6.7 1.6 1 1 0 1 1 1 0 PspA/IM30 family DUF1664 PF07889.7 EAQ88754.1 - 0.52 10.1 4.2 2.1 8.1 2.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TEX13 PF15186.1 EAQ88754.1 - 0.58 9.7 4.8 0.84 9.1 3.3 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Med4 PF10018.4 EAQ88754.1 - 0.66 9.3 6.8 1.2 8.5 4.7 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin-6_N PF09177.6 EAQ88754.1 - 0.75 10.2 7.8 2.1 8.8 3.9 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.9 EAQ88754.1 - 0.88 9.4 10.3 1.5 8.7 7.1 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HisKA_3 PF07730.8 EAQ88754.1 - 0.95 9.8 10.9 0.51 10.7 1.3 3.1 1 1 3 4 4 4 0 Histidine kinase DUF2564 PF10819.3 EAQ88754.1 - 1.1 9.4 7.5 0.33 11.0 0.3 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2564) DUF2746 PF10874.3 EAQ88754.1 - 1.1 9.4 3.7 2.5 8.3 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) KxDL PF10241.4 EAQ88754.1 - 1.2 9.1 5.8 1.4 8.8 3.4 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Prefoldin PF02996.12 EAQ88754.1 - 1.2 8.8 7.3 2.3 7.9 2.2 2.5 1 1 1 2 2 2 0 Prefoldin subunit COG2 PF06148.6 EAQ88754.1 - 1.3 8.8 5.1 0.93 9.3 2.2 1.8 2 1 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 V-SNARE PF05008.10 EAQ88754.1 - 1.6 8.9 7.1 5.2 7.3 4.8 2.0 2 1 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus Phasin_2 PF09361.5 EAQ88754.1 - 2.2 8.3 5.9 3.4 7.7 2.2 2.3 2 1 0 2 2 2 0 Phasin protein DivIVA PF05103.8 EAQ88754.1 - 2.3 8.3 8.7 3.4 7.7 3.0 2.1 2 0 0 2 2 2 0 DivIVA protein FliT PF05400.8 EAQ88754.1 - 2.3 8.6 12.3 4.3 7.8 7.9 1.8 2 0 0 2 2 1 0 Flagellar protein FliT zf-C4H2 PF10146.4 EAQ88754.1 - 2.3 8.1 6.4 0.31 11.0 1.7 1.5 2 0 0 2 2 1 0 Zinc finger-containing protein DUF4404 PF14357.1 EAQ88754.1 - 8.4 6.8 10.7 1.9 8.9 4.0 2.3 3 1 0 3 3 2 0 Domain of unknown function (DUF4404) ILVD_EDD PF00920.16 EAQ88756.1 - 3.9e-169 563.4 1.8 4.9e-169 563.0 1.3 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.11 EAQ88757.1 - 3.4e-131 437.1 4.8 4.3e-131 436.7 3.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PadR PF03551.9 EAQ88757.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF3184 PF11380.3 EAQ88757.1 - 0.19 9.6 0.0 0.25 9.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Tyrosinase PF00264.15 EAQ88759.1 - 1.4e-34 120.2 0.0 2.3e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Fe_hyd_SSU PF02256.12 EAQ88759.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Iron hydrogenase small subunit TPR_10 PF13374.1 EAQ88760.1 - 4.6e-72 236.0 0.0 2e-11 43.4 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88760.1 - 4.7e-63 209.0 0.0 4.3e-17 61.8 0.0 5.0 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ88760.1 - 7.4e-27 90.9 0.3 0.00017 21.1 0.0 7.4 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88760.1 - 1.7e-17 61.8 0.0 0.023 14.6 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ88760.1 - 1.4e-15 56.1 0.0 0.013 15.1 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ88760.1 - 1.6e-14 53.2 0.0 0.00034 20.1 0.0 5.1 1 1 5 6 6 6 5 TPR repeat TPR_17 PF13431.1 EAQ88760.1 - 1.8e-13 49.5 0.1 0.075 13.2 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ88760.1 - 5.2e-12 45.2 3.1 3.8 8.4 0.0 8.6 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ88760.1 - 5.8e-12 45.9 0.1 0.00039 20.9 0.0 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat PPR PF01535.15 EAQ88760.1 - 2.1e-11 42.9 1.0 0.38 10.8 0.0 6.8 6 0 0 6 6 6 2 PPR repeat TPR_8 PF13181.1 EAQ88760.1 - 1.2e-10 40.3 0.0 0.2 11.5 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ88760.1 - 1.5e-10 40.4 0.0 0.86 10.2 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ88760.1 - 1.8e-09 36.8 0.0 2e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EAQ88760.1 - 1.5e-08 34.8 1.0 0.25 11.7 0.0 5.7 4 2 3 7 7 6 4 Tetratricopeptide repeat PPR_3 PF13812.1 EAQ88760.1 - 1.7e-08 34.0 0.4 3.7 8.0 0.0 6.8 6 0 0 6 6 6 2 Pentatricopeptide repeat domain Apc3 PF12895.2 EAQ88760.1 - 5.2e-08 32.9 0.0 0.36 10.9 0.0 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Rab5-bind PF09311.6 EAQ88760.1 - 1.4e-06 28.3 0.4 1.4 8.7 0.0 4.3 1 1 4 5 5 5 1 Rabaptin-like protein TPR_5 PF12688.2 EAQ88760.1 - 4.4e-06 26.7 0.0 4.7 7.2 0.0 5.2 1 1 4 5 5 5 1 Tetratrico peptide repeat TPR_6 PF13174.1 EAQ88760.1 - 5e-06 26.6 6.7 4.8 7.8 0.0 7.0 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF4074 PF13293.1 EAQ88760.1 - 4.4e-05 23.6 0.6 2.8 8.2 0.0 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4074) PPR_2 PF13041.1 EAQ88760.1 - 0.00014 21.7 0.1 8.1 6.5 0.0 5.2 6 0 0 6 6 5 0 PPR repeat family TPR_3 PF07720.7 EAQ88760.1 - 0.00027 20.6 0.0 4.6 7.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 EAQ88760.1 - 0.0012 18.2 0.9 16 5.1 0.0 5.1 6 0 0 6 6 5 0 PPR repeat Euplotes_phero PF05842.6 EAQ88760.1 - 0.0017 18.7 3.9 33 4.8 0.0 4.9 1 1 4 5 5 5 0 Euplotes octocarinatus mating pheromone protein AAA_25 PF13481.1 EAQ88760.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain HrpB1_HrpK PF09613.5 EAQ88760.1 - 0.02 14.3 0.7 2.5 7.5 0.0 3.8 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) NACHT PF05729.7 EAQ88760.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Granin PF01271.12 EAQ88760.1 - 0.078 11.6 0.8 1.7 7.2 0.2 2.4 1 1 1 2 2 2 0 Granin (chromogranin or secretogranin) DDE_3 PF13358.1 EAQ88761.1 - 8.8e-10 38.5 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PIF1 PF05970.9 EAQ88761.1 - 1.3e-08 34.1 5.7 8.1e-05 21.7 0.7 2.3 1 1 1 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ88761.1 - 0.00079 19.5 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EAQ88761.1 - 0.0023 17.5 0.5 0.076 12.5 0.2 2.7 2 1 0 2 2 2 1 AAA domain GRA6 PF05084.8 EAQ88763.1 - 0.0035 16.8 1.2 0.007 15.9 0.8 1.4 1 0 0 1 1 1 1 Granule antigen protein (GRA6) PhzC-PhzF PF02567.11 EAQ88765.1 - 5.2e-44 150.5 0.0 1.6e-43 148.9 0.0 1.8 2 0 0 2 2 2 1 Phenazine biosynthesis-like protein Prp19 PF08606.6 EAQ88765.1 - 9e-31 105.4 1.0 2.3e-30 104.1 0.7 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EAQ88765.1 - 7.4e-10 38.3 1.0 0.0084 15.9 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.6 EAQ88765.1 - 3.6e-05 23.5 0.0 0.036 13.7 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EAQ88765.1 - 0.016 14.0 0.0 0.16 10.7 0.0 1.9 1 1 1 2 2 2 0 Coatomer WD associated region zf-Nse PF11789.3 EAQ88765.1 - 0.037 13.5 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EAQ88766.1 - 0.002 17.7 3.4 0.0066 16.1 2.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAQ88766.1 - 0.0055 16.7 0.4 0.0055 16.7 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ88766.1 - 0.01 15.4 2.6 0.028 14.0 1.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAQ88766.1 - 0.012 15.3 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAQ88766.1 - 0.059 13.2 1.0 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.7 EAQ88766.1 - 0.07 12.9 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbons FYVE PF01363.16 EAQ88766.1 - 0.14 12.0 2.1 0.66 9.9 1.4 1.9 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_2 PF13639.1 EAQ88766.1 - 0.15 11.9 3.5 0.2 11.5 0.9 2.0 2 0 0 2 2 2 0 Ring finger domain Nop14 PF04147.7 EAQ88766.1 - 0.28 9.0 5.2 0.31 8.9 3.6 1.1 1 0 0 1 1 1 0 Nop14-like family Upf2 PF04050.9 EAQ88766.1 - 1.4 8.7 8.4 2.4 7.9 5.8 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Daxx PF03344.10 EAQ88766.1 - 4.1 5.7 9.5 6.6 5.0 6.6 1.2 1 0 0 1 1 1 0 Daxx Family Peptidase_C14 PF00656.17 EAQ88767.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EAQ88767.1 - 0.00037 20.3 0.0 0.00057 19.7 0.0 1.2 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Pkinase PF00069.20 EAQ88771.1 - 4.3e-24 85.0 0.0 2.3e-23 82.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88771.1 - 3.8e-08 32.7 0.0 0.004 16.2 0.0 3.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EAQ88771.1 - 0.013 15.2 1.1 0.019 14.7 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.14 EAQ88774.1 - 4.3e-12 45.7 3.9 1.8e-06 27.2 0.7 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAQ88774.1 - 2.7e-05 24.1 0.1 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ88774.1 - 9.4e-05 21.4 0.0 0.00014 20.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EAQ88774.1 - 0.0011 19.3 0.1 0.025 14.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ88774.1 - 0.0034 16.3 0.1 0.097 11.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EAQ88774.1 - 0.057 12.0 0.1 3 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF4520 PF15016.1 EAQ88774.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) MFS_1 PF07690.11 EAQ88777.1 - 2e-35 122.1 32.1 7.5e-35 120.2 22.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EAQ88777.1 - 0.00079 19.7 0.8 0.00079 19.7 0.5 2.3 2 1 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4396 PF14342.1 EAQ88777.1 - 1.5 8.9 14.9 4.3 7.4 0.4 4.0 2 2 1 4 4 4 0 Domain of unknown function (DUF4396) MFS_1 PF07690.11 EAQ88778.1 - 4.1e-43 147.4 51.9 4.1e-43 147.4 36.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EAQ88779.1 - 9.8e-17 60.6 0.7 1.6e-16 59.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88779.1 - 7.1e-09 35.4 7.4 1.7e-08 34.1 5.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF932 PF06067.6 EAQ88780.1 - 0.1 11.8 3.7 0.2 10.9 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF932) U79_P34 PF03064.11 EAQ88780.1 - 0.37 10.2 7.8 0.5 9.8 5.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TFIIF_alpha PF05793.7 EAQ88781.1 - 0.18 10.1 8.0 0.24 9.7 5.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HPP PF04982.8 EAQ88782.1 - 3.5e-10 39.7 8.9 3.5e-10 39.7 6.2 2.9 2 1 0 2 2 2 1 HPP family IDO PF01231.13 EAQ88783.1 - 1.4e-31 109.3 0.0 2.1e-29 102.1 0.0 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.14 EAQ88784.1 - 3.1e-10 39.3 0.0 5.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EAQ88784.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family rve PF00665.21 EAQ88787.1 - 1.7e-11 44.2 0.0 3.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UbiA PF01040.13 EAQ88787.1 - 1.5e-05 24.3 0.1 2.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family SP_C-Propep PF08999.5 EAQ88789.1 - 0.33 10.4 2.3 0.53 9.8 0.5 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide AIG2 PF06094.7 EAQ88790.1 - 5.3e-17 62.1 0.1 8.8e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 AIG2-like family Helicase_C PF00271.26 EAQ88794.1 - 9.4e-20 70.2 0.1 1.8e-18 66.1 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ88794.1 - 1.5e-19 70.1 0.0 5.8e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EAQ88794.1 - 0.0068 15.2 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EAQ88794.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrmB PF01978.14 EAQ88794.1 - 0.044 13.4 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF1996 PF09362.5 EAQ88795.1 - 8e-89 297.3 0.5 9.6e-89 297.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Helicase_C_3 PF13625.1 EAQ88795.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Methyltransf_24 PF13578.1 EAQ88796.1 - 1.2e-08 35.6 0.0 1.9e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EAQ88796.1 - 0.00013 21.0 0.0 0.00067 18.7 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase DUF1768 PF08719.6 EAQ88796.1 - 0.14 11.8 0.1 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) Pro-kuma_activ PF09286.6 EAQ88797.1 - 2.1e-46 157.5 0.0 6.6e-45 152.6 0.0 2.4 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EAQ88797.1 - 2.6e-05 23.5 0.4 5.4e-05 22.4 0.3 1.5 1 0 0 1 1 1 1 Subtilase family Peptidase_C1 PF00112.18 EAQ88799.1 - 2.3e-26 93.0 0.6 2.3e-26 93.0 0.4 2.3 2 0 0 2 2 2 1 Papain family cysteine protease Flavin_Reduct PF01613.13 EAQ88800.1 - 7.9e-24 84.2 0.0 1.4e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain FAD_binding_4 PF01565.18 EAQ88800.1 - 5.2e-15 55.1 1.6 9.9e-15 54.2 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ88800.1 - 7.1e-05 22.6 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like LysM PF01476.15 EAQ88804.1 - 1.1e-15 57.2 0.0 0.00071 19.4 0.0 3.3 3 0 0 3 3 3 3 LysM domain Dmrt1 PF12374.3 EAQ88804.1 - 0.23 11.8 3.1 0.63 10.4 0.3 2.6 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Rubella_E2 PF05749.6 EAQ88804.1 - 0.61 9.2 7.6 0.027 13.7 0.6 1.9 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 3-dmu-9_3-mt PF06983.8 EAQ88805.1 - 2.6e-48 163.1 0.0 3.4e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Abhydrolase_6 PF12697.2 EAQ88808.1 - 6e-29 101.5 1.4 7.2e-29 101.2 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88808.1 - 4.8e-14 52.3 0.0 1.2e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ88808.1 - 5.3e-07 29.4 0.0 3.3e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAQ88808.1 - 4.2e-06 26.5 0.0 0.00026 20.7 0.0 3.4 3 2 1 4 4 4 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EAQ88808.1 - 0.0051 16.0 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EAQ88808.1 - 0.042 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein EHN PF06441.7 EAQ88808.1 - 0.12 12.2 0.1 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Tyrosinase PF00264.15 EAQ88809.1 - 1.4e-55 188.8 1.8 2.5e-55 188.0 1.3 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-RVT PF13966.1 EAQ88810.1 - 0.032 14.5 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase O-FucT PF10250.4 EAQ88811.1 - 8.2e-13 48.1 0.2 1.1e-10 41.1 0.1 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase WD40 PF00400.27 EAQ88812.1 - 2.8e-22 77.7 11.7 1.5e-10 40.5 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAQ88812.1 - 9.6e-18 63.8 0.0 2.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 EAQ88812.1 - 0.0088 14.8 0.2 0.35 9.5 0.1 2.5 1 1 1 2 2 2 2 Nup133 N terminal like Glyco_hydro_43 PF04616.9 EAQ88813.1 - 2.9e-32 111.9 6.5 3.7e-32 111.5 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase PF00069.20 EAQ88814.1 - 4.1e-14 52.3 0.0 9.6e-14 51.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88814.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase WW PF00397.21 EAQ88815.1 - 0.88 9.4 6.5 12 5.8 0.6 3.3 3 0 0 3 3 3 0 WW domain APH PF01636.18 EAQ88816.1 - 0.0016 18.2 1.1 0.0052 16.5 0.7 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1524 PF07510.6 EAQ88817.1 - 5.4e-13 49.0 0.1 6.6e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) PGAP1 PF07819.8 EAQ88818.1 - 0.00031 20.4 0.0 0.0055 16.3 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EAQ88818.1 - 0.00042 20.2 0.5 0.00086 19.2 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EAQ88818.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) zf-RanBP PF00641.13 EAQ88819.1 - 0.0011 18.0 1.7 0.0011 18.0 1.2 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Rep_fac-A_C PF08646.5 EAQ88819.1 - 0.11 12.2 1.3 0.14 11.8 0.9 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain Pkinase PF00069.20 EAQ88820.1 - 1e-06 28.1 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAQ88820.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ88820.1 - 0.0041 16.8 1.6 0.0085 15.8 1.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 EAQ88820.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 EAQ88820.1 - 0.14 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase SKG6 PF08693.5 EAQ88822.1 - 7.5e-05 21.9 1.8 0.00012 21.2 1.2 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EAQ88822.1 - 0.0011 17.2 0.3 0.0012 17.1 0.2 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 EAQ88822.1 - 0.0034 16.6 0.0 0.0044 16.2 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EAQ88822.1 - 0.0052 16.4 0.1 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 EAQ88822.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) NPDC1 PF06809.6 EAQ88822.1 - 0.025 13.3 2.3 0.029 13.1 1.6 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Med3 PF11593.3 EAQ88822.1 - 0.033 13.4 4.3 0.039 13.1 3.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4381 PF14316.1 EAQ88822.1 - 0.033 14.2 0.1 0.046 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2029 PF09594.5 EAQ88822.1 - 0.038 13.4 3.0 0.052 13.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Shisa PF13908.1 EAQ88822.1 - 0.075 13.2 0.3 0.17 12.0 0.2 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF4131 PF13567.1 EAQ88822.1 - 0.095 12.1 0.6 4.5 6.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) NfeD PF01957.13 EAQ88822.1 - 0.1 12.7 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Peptidase_M56 PF05569.6 EAQ88822.1 - 0.12 11.3 0.1 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3609 PF12259.3 EAQ88822.1 - 0.14 10.8 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) CcmD PF04995.9 EAQ88822.1 - 0.33 10.7 5.9 0.66 9.7 4.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MFS_1 PF07690.11 EAQ88823.1 - 6.4e-16 58.0 25.4 1e-15 57.3 17.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M61 PF05299.7 EAQ88826.1 - 7.2e-06 25.9 0.1 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_MA_2 PF13485.1 EAQ88826.1 - 0.011 15.8 0.4 0.019 14.9 0.3 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily DNMT1-RFD PF12047.3 EAQ88826.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Oxidored_q6 PF01058.17 EAQ88827.1 - 3.5e-06 26.6 0.1 5.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Ank PF00023.25 EAQ88828.1 - 1.5e-12 46.6 0.0 2.1e-06 27.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EAQ88828.1 - 1.7e-12 47.4 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ88828.1 - 1e-10 41.5 0.1 1.1e-05 25.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ88828.1 - 2.1e-09 36.7 0.0 0.00013 21.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EAQ88828.1 - 5.6e-09 36.2 0.0 8.9e-07 29.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Zn_clus PF00172.13 EAQ88828.1 - 4.1e-06 26.5 6.3 4.1e-06 26.5 4.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G6PD_bact PF10786.4 EAQ88828.1 - 0.073 12.4 0.3 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) MFS_1 PF07690.11 EAQ88829.1 - 4.1e-33 114.5 32.6 4.1e-33 114.5 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ88829.1 - 4.7e-12 45.2 24.8 4.1e-11 42.1 17.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ88829.1 - 1.9e-07 29.6 1.9 1.9e-07 29.6 1.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HET PF06985.6 EAQ88830.1 - 8.8e-17 61.5 0.3 6.7e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3050 PF11251.3 EAQ88830.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) adh_short PF00106.20 EAQ88831.1 - 1.2e-21 77.3 0.4 1.5e-21 77.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ88831.1 - 1.6e-13 50.7 0.2 2.1e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ88831.1 - 3.7e-08 33.4 0.0 4.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EAQ88831.1 - 1.4e-05 24.1 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EAQ88831.1 - 0.0014 18.3 0.1 0.0037 17.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAQ88831.1 - 0.062 12.7 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EAQ88832.1 - 7.3e-09 35.3 10.6 1.4e-08 34.4 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dabb PF07876.7 EAQ88833.1 - 1.6e-19 70.1 0.6 5.6e-17 61.9 0.4 2.1 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Aldo_ket_red PF00248.16 EAQ88834.1 - 1.3e-47 161.9 0.0 1.8e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidoligase_2 PF12224.3 EAQ88835.1 - 6.7e-12 45.5 0.0 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Thioredoxin PF00085.15 EAQ88836.1 - 6.8e-23 80.3 0.0 1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EAQ88836.1 - 9e-07 28.9 0.0 5e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EAQ88836.1 - 4.3e-06 26.6 0.0 8.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EAQ88836.1 - 4.9e-06 26.7 0.2 0.00011 22.3 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EAQ88836.1 - 9.6e-06 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAQ88836.1 - 0.00021 20.8 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 EAQ88836.1 - 0.0034 16.9 0.1 0.0083 15.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin WD40 PF00400.27 EAQ88837.1 - 5.6e-30 102.1 9.3 9.1e-10 38.0 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EAQ88837.1 - 0.053 13.2 0.0 2.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAQ88837.1 - 0.25 9.1 0.0 7.3 4.2 0.1 2.2 1 1 1 2 2 2 0 IKI3 family Aldo_ket_red PF00248.16 EAQ88838.1 - 1.1e-38 132.6 0.0 1.7e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.10 EAQ88839.1 - 4.6e-27 94.1 0.2 1e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EAQ88839.1 - 4.6e-19 69.0 0.1 8e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EAQ88839.1 - 1.1e-18 67.4 0.0 2.4e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 BCS1_N PF08740.6 EAQ88840.1 - 2.2e-40 138.2 0.4 2.2e-40 138.2 0.3 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EAQ88840.1 - 1.4e-16 60.9 0.0 3.9e-15 56.2 0.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAQ88840.1 - 9.8e-05 21.5 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EAQ88840.1 - 0.0011 18.3 0.1 0.0033 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ88840.1 - 0.0013 18.8 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAQ88840.1 - 0.0014 19.4 0.0 0.0014 19.4 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EAQ88840.1 - 0.005 16.5 0.4 0.013 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAQ88840.1 - 0.0054 16.4 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAQ88840.1 - 0.015 14.7 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 EAQ88840.1 - 0.036 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 EAQ88840.1 - 0.055 12.5 1.9 0.09 11.8 0.0 2.2 2 1 0 2 2 2 0 KaiC AAA_24 PF13479.1 EAQ88840.1 - 0.074 12.6 0.1 0.074 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EAQ88840.1 - 0.23 11.7 0.0 0.23 11.7 0.0 3.3 2 1 0 2 2 1 0 AAA domain DUF2215 PF10225.4 EAQ88840.1 - 0.61 9.4 4.5 8.9 5.6 3.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Borrelia_P83 PF05262.6 EAQ88840.1 - 1 7.5 21.9 1.5 6.9 15.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.15 EAQ88840.1 - 2.4 5.9 12.0 3.5 5.4 8.3 1.2 1 0 0 1 1 1 0 Hsp70 protein AAA_11 PF13086.1 EAQ88840.1 - 4.1 6.9 12.7 1e+02 2.3 8.8 2.4 1 1 0 1 1 1 0 AAA domain DUF1682 PF07946.9 EAQ88841.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ABC2_membrane PF01061.19 EAQ88842.1 - 2.3e-89 298.1 57.7 1.2e-45 155.3 19.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EAQ88842.1 - 3.4e-38 131.0 0.0 4.4e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EAQ88842.1 - 1.1e-34 118.2 0.1 2.2e-28 97.9 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter AAA_25 PF13481.1 EAQ88842.1 - 6.9e-09 35.3 0.1 1.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAQ88842.1 - 2.6e-07 30.5 0.1 0.00031 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 EAQ88842.1 - 1.2e-05 25.3 0.3 2.8e-05 24.1 0.0 1.8 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 EAQ88842.1 - 1.8e-05 24.1 1.8 0.0084 15.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EAQ88842.1 - 1.9e-05 23.9 23.5 1.9e-05 23.9 16.3 4.1 2 2 1 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 EAQ88842.1 - 0.00012 21.2 0.2 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAQ88842.1 - 0.00014 22.6 0.0 0.12 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EAQ88842.1 - 0.0017 17.6 0.0 10 5.2 0.0 3.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain OAR PF03826.12 EAQ88842.1 - 0.0033 16.8 0.1 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 OAR domain AAA_16 PF13191.1 EAQ88842.1 - 0.0041 17.1 0.8 0.21 11.5 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ88842.1 - 0.0043 17.2 0.1 0.36 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EAQ88842.1 - 0.0047 16.3 0.4 0.0047 16.3 0.3 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EAQ88842.1 - 0.0052 16.7 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ88842.1 - 0.0063 16.9 0.1 4.1 7.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EAQ88842.1 - 0.0066 16.1 0.7 1.5 8.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EAQ88842.1 - 0.011 15.7 0.3 0.044 13.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EAQ88842.1 - 0.011 16.0 0.3 0.65 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EAQ88842.1 - 0.016 15.1 0.0 0.16 11.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EAQ88842.1 - 0.016 15.4 0.1 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EAQ88842.1 - 0.036 14.2 0.2 12 6.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EAQ88842.1 - 0.07 12.8 1.4 9.6 6.0 0.5 2.7 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EAQ88842.1 - 0.13 12.3 0.1 25 5.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EAQ88842.1 - 0.14 11.6 0.2 19 4.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EAQ88842.1 - 0.22 11.1 1.7 0.82 9.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EAQ88842.1 - 0.35 10.2 0.6 22 4.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF4246 PF14033.1 EAQ88843.1 - 8.4e-177 588.7 0.0 9.8e-177 588.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) WSC PF01822.14 EAQ88844.1 - 3e-36 123.2 22.3 1.8e-18 66.2 6.4 2.1 2 0 0 2 2 2 2 WSC domain LysM PF01476.15 EAQ88845.1 - 8.6e-13 47.9 1.7 0.0028 17.5 0.0 4.6 5 0 0 5 5 5 3 LysM domain Sporozoite_P67 PF05642.6 EAQ88846.1 - 0.25 9.1 1.2 0.3 8.9 0.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 EAQ88846.1 - 2.1 8.3 6.4 3.8 7.5 4.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Zip PF02535.17 EAQ88851.1 - 2.6e-23 82.5 6.0 2.5e-12 46.4 1.0 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter DUF2763 PF10961.3 EAQ88851.1 - 0.08 13.3 0.6 0.18 12.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) PI-PLC-X PF00388.14 EAQ88853.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_17 PF00332.13 EAQ88855.1 - 4.3e-06 25.9 0.8 1.2e-05 24.5 0.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 ShlB PF03865.8 EAQ88855.1 - 0.041 12.6 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB PFO_beta_C PF12367.3 EAQ88855.1 - 0.34 10.8 1.4 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal PBP1_TM PF14812.1 EAQ88856.1 - 0.22 11.8 1.5 0.64 10.3 1.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.18 EAQ88857.1 - 2.2e-56 191.4 0.0 2.9e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ88857.1 - 6.6e-10 39.1 1.5 1.4e-08 34.8 0.1 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAQ88857.1 - 0.007 15.9 0.0 0.3 10.6 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal ADH_zinc_N_2 PF13602.1 EAQ88858.1 - 1.7e-23 83.9 0.0 6.5e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EAQ88858.1 - 1.1e-15 57.3 0.6 2e-15 56.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EAQ88858.1 - 0.02 14.3 0.2 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EAQ88858.1 - 0.027 13.4 0.6 0.041 12.8 0.4 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EAQ88858.1 - 0.032 14.2 1.4 0.053 13.5 1.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EAQ88858.1 - 0.032 14.1 1.9 0.067 13.0 1.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N PF08240.7 EAQ88858.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 EAQ88858.1 - 0.064 13.1 0.9 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PTCB-BRCT PF12738.2 EAQ88859.1 - 1.5e-44 149.6 0.2 6.1e-21 74.0 0.0 4.6 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 EAQ88859.1 - 2.8e-35 120.2 0.0 5.2e-11 42.5 0.0 4.6 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain NUDIX PF00293.23 EAQ88859.1 - 1.3e-11 44.2 0.3 2.8e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain MIP-T3 PF10243.4 EAQ88860.1 - 0.11 10.9 33.1 0.22 9.9 22.9 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA PF00004.24 EAQ88863.1 - 7.1e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ88863.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ88863.1 - 0.00083 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EAQ88863.1 - 0.0018 17.0 0.0 0.0057 15.4 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EAQ88863.1 - 0.0023 17.9 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAQ88863.1 - 0.0034 18.1 0.0 0.01 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAQ88863.1 - 0.013 15.2 0.0 0.033 13.8 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EAQ88863.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 EAQ88863.1 - 0.31 9.6 0.0 0.49 9.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Serglycin PF04360.7 EAQ88864.1 - 4.5 6.9 11.0 1 9.1 5.1 1.7 2 0 0 2 2 2 0 Serglycin DUF2422 PF10337.4 EAQ88865.1 - 4.4e-121 404.8 0.1 4.4e-121 404.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EAQ88865.1 - 3.9e-09 36.5 11.6 3.9e-09 36.5 8.1 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EAQ88865.1 - 7.5e-06 25.7 0.0 0.07 12.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2421) DUF834 PF05754.9 EAQ88865.1 - 4.4 7.1 7.0 1.3 8.8 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF834) FA_desaturase PF00487.19 EAQ88866.1 - 2.2e-27 96.1 29.3 4.7e-27 95.0 20.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EAQ88866.1 - 4.2e-08 33.2 0.1 7.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fungal_trans PF04082.13 EAQ88867.1 - 1.3e-10 40.5 0.0 2.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EAQ88868.1 - 3.1e-09 36.6 12.5 0.0003 20.9 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ88868.1 - 4.1e-07 29.9 6.4 4.1e-07 29.9 4.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ88868.1 - 7.3e-06 25.9 13.7 0.011 15.9 2.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ88868.1 - 0.051 13.7 3.8 0.47 10.6 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ88868.1 - 0.057 13.6 1.0 0.057 13.6 0.7 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAQ88868.1 - 0.25 11.3 8.5 0.15 11.9 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger MOSC_N PF03476.11 EAQ88871.1 - 1.4e-13 50.5 0.0 3.4e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EAQ88871.1 - 3.3e-13 49.2 0.0 5.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Abhydrolase_6 PF12697.2 EAQ88872.1 - 1.8e-19 70.5 0.3 2.2e-19 70.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ88872.1 - 9.9e-06 25.3 0.0 1.5e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ88872.1 - 2.7e-05 23.8 0.1 7.1e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.16 EAQ88873.1 - 1.7e-29 101.9 0.0 2.4e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF202 PF02656.10 EAQ88874.1 - 0.25 11.6 0.2 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PIG-L PF02585.12 EAQ88875.1 - 1.3e-24 87.1 0.0 1.8e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RAI16-like PF10257.4 EAQ88876.1 - 0.086 11.7 0.0 0.094 11.6 0.0 1.0 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein GTP_EFTU PF00009.22 EAQ88877.1 - 1.7e-21 76.5 0.0 3.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAQ88877.1 - 6.9e-15 55.0 0.0 1.7e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAQ88877.1 - 1.5e-10 40.9 1.0 2e-09 37.4 0.6 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAQ88877.1 - 0.00062 19.6 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EAQ88877.1 - 0.0012 18.3 0.7 0.25 10.8 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EAQ88877.1 - 0.0018 18.7 0.2 0.021 15.3 0.2 2.6 2 1 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EAQ88877.1 - 0.02 14.0 0.2 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAQ88877.1 - 0.05 13.4 0.1 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Dynamin family LDB19 PF13002.2 EAQ88878.1 - 1.6e-37 128.8 0.2 2.5e-37 128.2 0.1 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EAQ88878.1 - 1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EAQ88878.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein SQS_PSY PF00494.14 EAQ88880.1 - 3.1e-55 187.3 0.0 3.9e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 EAQ88881.1 - 2.6e-70 236.5 0.0 3.6e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EAQ88881.1 - 1.8e-24 85.6 0.0 3.9e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EAQ88881.1 - 4.6e-14 52.0 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EAQ88881.1 - 1.9e-06 27.7 10.6 4e-06 26.7 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ88881.1 - 0.00066 19.2 11.2 0.0013 18.3 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ88881.1 - 0.0014 18.2 8.6 0.0027 17.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ88881.1 - 0.017 14.9 11.6 0.045 13.5 8.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EAQ88881.1 - 0.44 10.3 10.0 1 9.1 7.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Helitron_like_N PF14214.1 EAQ88882.1 - 8.1e-42 143.0 0.4 1.5e-41 142.1 0.3 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ88882.1 - 1e-28 100.3 0.0 5.5e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ88882.1 - 1.7e-06 27.7 0.0 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ88882.1 - 0.00015 21.4 0.1 0.00045 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ88882.1 - 0.00023 19.0 0.0 0.00043 18.1 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ88882.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF605 PF04652.11 EAQ88882.1 - 4.8 6.4 7.5 8.9 5.5 5.2 1.3 1 0 0 1 1 1 0 Vta1 like DDE_1 PF03184.14 EAQ88883.1 - 6.1e-56 188.9 0.0 3.5e-55 186.4 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ88883.1 - 1.1e-12 47.5 0.3 3.9e-12 45.7 0.0 2.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ88883.1 - 4.7e-12 45.2 0.0 8.9e-12 44.3 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EAQ88883.1 - 3.6e-05 23.2 0.0 0.00012 21.6 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DUF3093 PF11292.3 EAQ88883.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) HTH_28 PF13518.1 EAQ88883.1 - 0.15 12.1 0.6 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Helitron_like_N PF14214.1 EAQ88884.1 - 1.8e-20 73.4 0.0 5.1e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DDE_1 PF03184.14 EAQ88884.1 - 1.2e-06 27.8 0.0 3.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ88884.1 - 8.2e-05 22.3 0.0 0.00027 20.7 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FAR1 PF03101.10 EAQ88884.1 - 0.23 11.9 0.3 0.56 10.7 0.2 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain DDE_1 PF03184.14 EAQ88885.1 - 2.7e-55 186.8 0.0 1.1e-54 184.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ88885.1 - 2.2e-12 46.5 0.1 7.9e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ88885.1 - 8.4e-12 44.4 0.0 1.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EAQ88885.1 - 5.7e-05 22.6 0.0 0.00022 20.7 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.14 EAQ88886.1 - 3.9e-49 166.7 0.0 5.4e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ88886.1 - 0.00071 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ88886.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain PBP1_TM PF14812.1 EAQ88887.1 - 0.022 15.0 0.9 0.022 15.0 0.6 1.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EAQ88887.1 - 0.064 12.7 0.6 0.071 12.6 0.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF688 PF05097.7 EAQ88887.1 - 0.2 10.5 1.7 0.25 10.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Osteopontin PF00865.13 EAQ88887.1 - 0.35 10.0 7.2 0.38 9.9 5.0 1.1 1 0 0 1 1 1 0 Osteopontin DDE_1 PF03184.14 EAQ88888.1 - 4.8e-50 169.7 0.0 5.5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ88888.1 - 4.1e-05 23.3 0.0 5.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EAQ88889.1 - 6.3e-33 113.9 0.0 8.6e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EAQ88890.1 - 6.4e-44 149.6 0.3 4.8e-43 146.8 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ88890.1 - 3e-05 23.7 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EAQ88891.1 - 1.2e-16 60.9 0.0 2.7e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EAQ88891.1 - 4.1e-10 39.3 0.0 7.1e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ88891.1 - 0.021 14.5 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DnaB_2 PF07261.6 EAQ88891.1 - 0.044 13.3 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment zf-H2C2 PF09337.5 EAQ88891.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger RVP_2 PF08284.6 EAQ88892.1 - 0.063 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Pneumo_att_G PF05539.6 EAQ88892.1 - 1.3 8.3 10.9 1.8 7.8 7.5 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G plasmid_Toxin PF12703.2 EAQ88893.1 - 0.63 9.8 2.9 0.62 9.9 0.2 2.2 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system PAPS_reduct PF01507.14 EAQ88894.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Carb_bind PF10645.4 EAQ88895.1 - 6.7e-29 99.4 7.3 1.4e-28 98.4 5.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding IGFL PF14653.1 EAQ88895.1 - 0.028 14.4 1.0 2.2 8.3 1.9 2.2 1 1 1 2 2 2 0 Insulin growth factor-like family Amb_V_allergen PF03913.8 EAQ88895.1 - 0.039 13.6 1.0 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Amb V Allergen CorA PF01544.13 EAQ88896.1 - 2.2e-26 92.5 2.8 3.8e-21 75.3 0.4 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein MULE PF10551.4 EAQ88897.1 - 1.8e-13 50.4 0.0 4.4e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ88897.1 - 0.015 13.9 0.0 0.029 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family TYA PF01021.14 EAQ88898.1 - 0.011 15.9 0.6 0.015 15.4 0.4 1.3 1 0 0 1 1 1 0 TYA transposon protein SNF2_N PF00176.18 EAQ88899.1 - 7.7e-38 129.9 0.9 2.2e-34 118.6 0.6 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_5 PF14634.1 EAQ88899.1 - 0.00015 21.4 13.8 0.00041 20.0 8.9 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAQ88899.1 - 0.00017 21.1 11.6 0.0004 19.9 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ88899.1 - 0.00042 20.1 9.7 0.00097 18.9 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EAQ88899.1 - 0.00079 19.4 11.8 0.0017 18.3 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ESCRT-II PF05871.7 EAQ88899.1 - 0.003 17.4 1.0 0.004 17.0 0.2 1.5 2 0 0 2 2 2 1 ESCRT-II complex subunit zf-C3HC4_3 PF13920.1 EAQ88899.1 - 0.01 15.5 10.3 0.024 14.3 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EAQ88899.1 - 0.042 13.6 5.9 0.1 12.4 4.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PriCT_1 PF08708.6 EAQ88899.1 - 0.049 13.4 0.1 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) zf-RING_UBOX PF13445.1 EAQ88899.1 - 0.29 10.8 5.7 1.2 8.9 3.8 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EAQ88899.1 - 3.8 7.4 13.0 59 3.6 7.4 2.6 1 1 1 2 2 2 0 Ring finger domain Helicase_C PF00271.26 EAQ88900.1 - 0.0016 18.2 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.9 EAQ88900.1 - 9.2 4.1 8.6 12 3.7 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_2 PF00891.13 EAQ88901.1 - 3e-37 128.1 0.0 3.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAQ88901.1 - 0.0069 16.9 0.0 0.028 14.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAQ88901.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TauD PF02668.11 EAQ88902.1 - 2.8e-51 174.6 0.0 3.5e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FMO-like PF00743.14 EAQ88903.1 - 2.9e-34 118.1 0.0 6.9e-16 57.5 0.0 3.2 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EAQ88903.1 - 1.6e-20 74.0 0.5 1.1e-18 67.9 0.4 2.9 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ88903.1 - 4.6e-10 38.9 7.8 2.2e-09 36.6 0.2 3.6 3 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ88903.1 - 1.2e-08 35.1 0.0 0.012 15.4 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ88903.1 - 1.7e-08 34.3 8.9 2.7e-05 23.9 0.3 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAQ88903.1 - 2e-08 34.1 1.6 1.9e-07 30.9 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EAQ88903.1 - 2.1e-08 33.4 1.6 1e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EAQ88903.1 - 1.8e-06 27.2 0.2 0.03 13.4 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EAQ88903.1 - 0.0001 21.5 0.2 0.00058 19.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ88903.1 - 0.00028 20.0 2.9 0.00039 19.6 1.0 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EAQ88903.1 - 0.0034 15.9 1.1 0.01 14.3 1.0 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EAQ88903.1 - 0.0085 14.9 0.1 0.057 12.2 0.1 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAQ88903.1 - 0.01 14.6 2.1 0.01 14.6 1.5 2.2 3 0 0 3 3 3 0 FAD binding domain DJ-1_PfpI PF01965.19 EAQ88903.1 - 0.02 14.3 0.0 7 6.0 0.1 2.4 2 0 0 2 2 2 0 DJ-1/PfpI family Pyr_redox PF00070.22 EAQ88903.1 - 0.022 15.1 10.3 0.037 14.4 0.7 3.2 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EAQ88903.1 - 0.026 14.6 0.4 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EAQ88903.1 - 0.044 13.4 0.9 0.077 12.6 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EAQ88903.1 - 0.059 13.6 0.2 8.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EAQ88903.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 EAQ88903.1 - 0.56 9.1 6.4 0.036 13.1 0.5 1.8 3 0 0 3 3 3 0 FAD binding domain DUF2293 PF10056.4 EAQ88904.1 - 1.1e-32 111.8 0.7 2.9e-32 110.4 0.5 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) GAGA_bind PF06217.7 EAQ88904.1 - 0.033 14.1 0.8 0.05 13.5 0.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Scytalone_dh PF02982.9 EAQ88905.1 - 4.6e-90 299.3 0.4 5.3e-90 299.1 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EAQ88905.1 - 7.6e-06 25.8 0.1 1e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF3722 PF12519.3 EAQ88906.1 - 4e-84 281.8 0.1 5.3e-84 281.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Zip PF02535.17 EAQ88907.1 - 6.8e-51 173.1 6.8 9.2e-51 172.7 4.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter PIG-P PF08510.7 EAQ88907.1 - 0.0013 18.3 0.4 0.0046 16.5 0.0 2.0 2 1 0 2 2 2 1 PIG-P Ank PF00023.25 EAQ88908.1 - 5.5e-09 35.3 0.8 2.1e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EAQ88908.1 - 1e-08 35.1 0.6 1.8e-08 34.3 0.1 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ88908.1 - 1e-07 32.1 0.1 3.2e-07 30.5 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ88908.1 - 7.1e-05 23.2 0.1 0.024 15.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ88908.1 - 0.00052 19.9 0.1 0.0042 17.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ribosomal_S19e PF01090.14 EAQ88909.1 - 1.5e-57 192.9 0.7 1.7e-57 192.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 EAQ88909.1 - 0.068 13.1 0.1 0.086 12.8 0.1 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Ricin_B_lectin PF00652.17 EAQ88910.1 - 8.9e-15 54.8 0.2 2.4e-05 24.3 0.0 3.7 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain BSP_II PF05432.6 EAQ88910.1 - 0.88 8.7 9.9 1.4 8.1 6.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Fe-S_biosyn PF01521.15 EAQ88911.1 - 2.9e-11 43.2 0.0 6.4e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 EAQ88912.1 - 7.3e-27 93.1 17.4 1.1e-26 92.5 12.0 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EAQ88912.1 - 1.8e-19 69.0 2.8 2.1e-19 68.8 0.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e FRG1 PF06229.7 EAQ88912.1 - 0.13 11.6 4.3 0.23 10.9 3.0 1.3 1 0 0 1 1 1 0 FRG1-like family Ribosomal_S11 PF00411.14 EAQ88913.1 - 1.4e-40 137.8 0.5 1.8e-40 137.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EAQ88913.1 - 0.03 13.2 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) eIF-3c_N PF05470.7 EAQ88915.1 - 1.3e-172 575.0 19.1 1.3e-172 575.0 13.2 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EAQ88915.1 - 2e-14 53.7 0.3 2.2e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 PCI domain PROCN PF08083.6 EAQ88916.1 - 5.3e-220 729.9 10.4 8.2e-220 729.3 7.2 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EAQ88916.1 - 7.5e-126 418.0 1.7 1.3e-125 417.3 1.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EAQ88916.1 - 5.7e-94 311.8 1.1 1.4e-93 310.5 0.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EAQ88916.1 - 7.9e-77 256.0 3.0 7.9e-77 256.0 2.1 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EAQ88916.1 - 5.8e-67 223.4 0.1 1.4e-66 222.2 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EAQ88916.1 - 2.5e-44 149.9 0.2 7.2e-44 148.5 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EAQ88916.1 - 8.2e-44 147.3 0.1 2.2e-43 146.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 EAQ88916.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Myb_DNA-bind_6 PF13921.1 EAQ88917.1 - 1.3e-15 57.2 0.1 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ88917.1 - 1.1e-12 47.7 0.2 4.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 EAQ88917.1 - 0.04 13.4 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF4085 PF13315.1 EAQ88917.1 - 0.087 12.1 0.1 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) SNF2_N PF00176.18 EAQ88918.1 - 4.3e-65 219.4 0.0 6e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ88918.1 - 7.8e-17 60.9 0.0 2.2e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EAQ88918.1 - 0.00048 19.0 0.0 0.0009 18.1 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EAQ88918.1 - 0.048 13.4 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Hemerythrin PF01814.18 EAQ88919.1 - 8e-10 38.9 5.0 1.8e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 Hemerythrin HHE cation binding domain Mpv17_PMP22 PF04117.7 EAQ88921.1 - 6.2e-13 48.1 2.1 7e-12 44.7 1.8 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.11 EAQ88922.1 - 1.1e-64 217.7 0.0 1.6e-64 217.1 0.0 1.3 1 1 0 1 1 1 1 EAP30/Vps36 family Transgly PF00912.17 EAQ88922.1 - 0.026 13.8 0.1 0.052 12.8 0.0 1.5 2 0 0 2 2 2 0 Transglycosylase AAR2 PF05282.6 EAQ88923.1 - 6.6e-51 173.3 0.0 3.8e-50 170.8 0.0 1.9 1 1 0 1 1 1 1 AAR2 protein TatC PF00902.13 EAQ88923.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Gag_p17 PF00540.13 EAQ88924.1 - 0.94 9.2 3.8 0.23 11.2 0.1 1.7 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) DEAD PF00270.24 EAQ88926.1 - 4.9e-45 153.0 0.0 1.1e-43 148.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ88926.1 - 1.4e-28 98.5 0.0 2.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ88926.1 - 7.3e-05 22.6 0.0 0.00023 21.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EAQ88926.1 - 0.00069 18.1 0.0 0.038 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EAQ88926.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF2443 PF10398.4 EAQ88926.1 - 0.023 14.5 0.3 0.05 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Phos_pyr_kin PF08543.7 EAQ88927.1 - 3.9e-81 271.8 0.7 6.1e-81 271.2 0.5 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EAQ88927.1 - 3.1e-36 125.1 0.1 6.5e-20 71.7 0.0 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 EAQ88927.1 - 1.3e-05 24.5 0.1 3e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EAQ88927.1 - 0.095 11.8 3.3 0.18 10.9 0.1 2.4 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family RICTOR_N PF14664.1 EAQ88928.1 - 7.7e-113 376.8 2.6 4.5e-84 282.1 0.0 3.4 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EAQ88928.1 - 2.1e-90 301.6 0.2 5e-89 297.1 0.1 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EAQ88928.1 - 6.8e-43 145.2 0.0 3.2e-41 139.8 0.0 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EAQ88928.1 - 2.2e-26 91.6 2.9 9e-26 89.6 0.1 3.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EAQ88928.1 - 6e-13 48.3 5.8 1.4e-12 47.1 4.0 1.7 1 0 0 1 1 1 1 Hr1 repeat Arm PF00514.18 EAQ88928.1 - 0.85 9.5 2.5 7.9 6.4 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TFIIA PF03153.8 EAQ88928.1 - 1.5 8.6 39.2 3.5 7.4 12.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Uricase PF01014.13 EAQ88929.1 - 5.3e-83 275.9 0.2 1.8e-45 154.4 0.7 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 EAQ88930.1 - 1e-37 129.0 0.0 1.4e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.21 EAQ88931.1 - 5.3e-14 52.1 0.1 8.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EAQ88931.1 - 1.9e-11 44.2 0.0 3.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Axin_b-cat_bind PF08833.5 EAQ88932.1 - 0.85 9.3 8.5 12 5.7 2.0 3.1 2 1 0 2 2 2 0 Axin beta-catenin binding domain TPR_11 PF13414.1 EAQ88933.1 - 1.7e-20 72.4 10.7 3.9e-10 39.2 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EAQ88933.1 - 2.2e-16 58.6 9.0 3.4e-08 32.7 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88933.1 - 4.2e-14 51.2 5.2 7.2e-06 25.5 0.0 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88933.1 - 3.5e-13 49.2 0.7 1.1e-07 31.6 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ88933.1 - 1.6e-11 43.1 3.8 2e-05 24.0 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 EAQ88933.1 - 1.7e-07 30.8 0.2 3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 EAQ88933.1 - 5.3e-07 29.3 0.1 0.0047 17.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ88933.1 - 1.1e-06 28.7 2.3 0.12 12.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ88933.1 - 3.5e-06 26.4 0.5 0.00014 21.3 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ88933.1 - 8.7e-06 25.4 0.5 0.017 14.9 0.0 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ88933.1 - 1.4e-05 25.5 1.4 0.0022 18.6 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ88933.1 - 0.00083 19.7 0.3 0.046 14.3 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EAQ88933.1 - 0.084 12.7 0.1 0.61 9.9 0.0 2.5 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 EAQ88933.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_19 PF14559.1 EAQ88933.1 - 0.091 13.1 0.2 0.46 10.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EAQ88933.1 - 0.32 11.1 3.5 1.1 9.5 0.2 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FAR1 PF03101.10 EAQ88934.1 - 0.00029 21.3 0.4 0.00029 21.3 0.3 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain HSBP1 PF06825.7 EAQ88934.1 - 0.0043 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Heat shock factor binding protein 1 AFT PF08731.6 EAQ88934.1 - 0.023 14.9 0.5 0.023 14.9 0.3 2.3 2 0 0 2 2 2 0 Transcription factor AFT BAF1_ABF1 PF04684.8 EAQ88934.1 - 0.18 10.6 23.3 0.26 10.0 16.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 EAQ88934.1 - 0.2 9.8 5.2 0.24 9.6 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EAQ88934.1 - 1.4 7.8 4.8 2.6 6.9 3.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L34e PF01199.13 EAQ88936.1 - 1.4e-36 124.6 2.7 1.9e-36 124.1 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 EAQ88936.1 - 0.21 11.2 3.7 2.5 7.8 0.2 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.9 EAQ88937.1 - 7e-20 70.6 0.1 1.1e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CMAS PF02353.15 EAQ88938.1 - 5.9e-62 209.2 0.1 7.3e-62 208.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAQ88938.1 - 2.4e-12 46.8 0.0 5.7e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ88938.1 - 1.1e-06 28.9 0.0 2.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ88938.1 - 0.003 18.1 0.0 0.018 15.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ88938.1 - 0.0045 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ88938.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EAQ88938.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 EAQ88938.1 - 0.099 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Alpha-amylase PF00128.19 EAQ88939.1 - 1.2e-88 297.5 0.1 2e-88 296.8 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Cellulase PF00150.13 EAQ88939.1 - 0.0019 17.4 0.0 0.0045 16.2 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.1 EAQ88939.1 - 0.026 13.4 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 EAQ88939.1 - 0.1 12.1 0.2 0.8 9.2 0.0 2.5 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain G-patch_2 PF12656.2 EAQ88940.1 - 1.5e-16 59.9 0.1 1.3e-15 56.9 0.1 2.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site Pneumo_att_G PF05539.6 EAQ88940.1 - 0.42 9.9 7.1 0.61 9.3 4.9 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G HSA PF07529.8 EAQ88941.1 - 4.6e-19 67.9 1.2 4.6e-19 67.9 0.8 4.2 4 0 0 4 4 4 2 HSA Myb_DNA-bind_6 PF13921.1 EAQ88941.1 - 1.2e-12 47.7 0.2 1.2e-12 47.7 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ88941.1 - 0.0021 18.0 0.2 0.005 16.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 EAQ88942.1 - 1.9e-13 49.6 0.0 0.0024 17.6 0.0 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1174 PF06671.6 EAQ88942.1 - 0.53 9.9 4.9 1.1 8.9 3.4 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) INSIG PF07281.7 EAQ88943.1 - 1.7e-52 177.5 0.0 3.6e-52 176.5 0.0 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Pex14_N PF04695.8 EAQ88943.1 - 0.016 15.2 0.3 0.17 11.9 0.0 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_gE PF02480.11 EAQ88943.1 - 0.048 11.9 0.8 1 7.5 0.1 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E HemX PF04375.9 EAQ88943.1 - 0.13 10.8 0.1 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 HemX bHLH-MYC_N PF14215.1 EAQ88943.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal zf-C3HC4_4 PF15227.1 EAQ88944.1 - 1.7e-10 40.5 20.1 2.6e-06 27.2 2.7 2.9 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EAQ88944.1 - 6.8e-10 38.6 22.1 1.2e-05 25.0 5.1 3.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ88944.1 - 1e-09 38.2 22.9 1.7e-05 24.7 5.8 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ88944.1 - 1.1e-09 37.8 17.5 3.3e-06 26.7 4.5 2.7 2 0 0 2 2 2 2 zinc-RING finger domain LON PF02190.11 EAQ88944.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EAQ88944.1 - 1.2e-08 34.4 13.5 3e-06 26.7 3.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ88944.1 - 1.5e-08 34.1 16.5 1.4e-05 24.6 5.4 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EAQ88944.1 - 0.0038 16.7 1.8 0.0038 16.7 1.3 3.2 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EAQ88944.1 - 0.032 13.9 18.4 0.11 12.2 2.0 3.3 3 0 0 3 3 3 0 RING-type zinc-finger zf-rbx1 PF12678.2 EAQ88944.1 - 5 7.2 12.5 0.47 10.5 3.3 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger FYVE PF01363.16 EAQ88944.1 - 8.5 6.3 10.7 7.6 6.5 0.3 3.4 3 1 1 4 4 4 0 FYVE zinc finger efThoc1 PF11957.3 EAQ88945.1 - 1.1e-139 466.1 5.4 4.6e-89 299.1 0.6 2.1 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 EAQ88945.1 - 2.6e-20 72.6 0.0 2.2e-19 69.6 0.0 2.2 2 0 0 2 2 2 1 Guanylate kinase AAA_12 PF13087.1 EAQ88946.1 - 4.3e-27 94.7 0.0 7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAQ88946.1 - 3.1e-22 79.2 0.0 7.6e-22 78.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ88946.1 - 7.5e-09 35.2 0.0 9.6e-08 31.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAQ88946.1 - 2.8e-07 30.3 0.0 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EAQ88946.1 - 0.00023 21.0 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EAQ88946.1 - 0.002 17.5 0.1 0.0094 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EAQ88946.1 - 0.0023 18.1 0.0 0.0061 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EAQ88946.1 - 0.0043 16.6 0.2 0.22 10.9 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EAQ88946.1 - 0.0061 16.6 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ88946.1 - 0.011 15.7 0.0 0.042 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EAQ88946.1 - 0.018 14.1 0.0 0.047 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.24 EAQ88946.1 - 0.021 14.3 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EAQ88946.1 - 0.061 14.1 0.0 0.81 10.5 0.0 3.0 3 0 0 3 3 1 0 AAA domain DUF2075 PF09848.4 EAQ88946.1 - 0.069 12.1 1.2 0.085 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EAQ88946.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 EAQ88946.1 - 0.13 11.1 0.0 8.9 5.1 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DnaB_C PF03796.10 EAQ88946.1 - 0.15 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain UvrD-helicase PF00580.16 EAQ88946.1 - 0.21 10.8 0.0 0.63 9.2 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Parvo_NS1 PF01057.12 EAQ88946.1 - 0.25 10.1 0.0 0.41 9.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIF4G PF02854.14 EAQ88948.1 - 3.7e-42 144.0 0.0 6.6e-41 140.0 0.0 2.1 1 1 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EAQ88948.1 - 5.5e-22 77.4 0.4 1.4e-21 76.1 0.2 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 EAQ88948.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DNA_pol_B PF00136.16 EAQ88949.1 - 1.3e-108 363.8 0.1 2.2e-108 363.0 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EAQ88949.1 - 6.4e-65 218.0 0.0 1.2e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EAQ88949.1 - 3.8e-40 137.7 0.0 9e-40 136.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EAQ88949.1 - 9e-24 83.0 11.2 9e-24 83.0 7.7 2.8 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 EAQ88950.1 - 3.2e-24 84.6 3.3 5.3e-15 55.1 0.0 5.6 4 2 2 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EAQ88950.1 - 1.1e-08 34.6 10.2 0.0055 16.8 0.0 7.4 8 1 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 EAQ88950.1 - 4.8e-07 29.3 2.1 0.0019 18.0 0.0 5.3 5 1 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 EAQ88950.1 - 1.3e-05 24.5 0.2 0.016 14.6 0.0 4.3 6 0 0 6 6 6 1 PPR repeat RRM_1 PF00076.17 EAQ88952.1 - 1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ88952.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ88952.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EAQ88952.1 - 0.0038 17.2 0.6 0.0038 17.2 0.4 1.7 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding DUF605 PF04652.11 EAQ88952.1 - 9.6 5.4 8.6 0.65 9.3 1.8 1.8 2 0 0 2 2 2 0 Vta1 like Pkinase PF00069.20 EAQ88953.1 - 3.3e-50 170.6 0.1 1.1e-49 168.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88953.1 - 2.5e-21 75.9 0.0 5.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ88953.1 - 0.00054 19.7 0.1 0.00054 19.7 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EAQ88953.1 - 0.0028 17.0 0.3 0.0098 15.2 0.2 1.8 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EAQ88953.1 - 0.24 10.9 2.0 0.44 10.0 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.17 EAQ88954.1 - 1.2e-47 159.4 0.0 4.6e-21 74.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ88954.1 - 1.3e-29 101.9 0.0 1e-12 47.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ88954.1 - 3.6e-24 84.3 0.0 5.2e-09 35.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAQ88954.1 - 0.0077 15.9 0.0 5.9 6.7 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cellulase PF00150.13 EAQ88956.1 - 9.5e-18 64.3 0.2 2e-17 63.2 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PH PF00169.24 EAQ88957.1 - 2e-24 85.8 2.2 2.9e-16 59.5 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EAQ88957.1 - 2.1e-09 37.5 2.1 1.3e-06 28.5 0.4 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EAQ88957.1 - 6.8e-09 35.9 8.0 3.4e-06 27.2 0.1 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EAQ88957.1 - 0.0039 17.2 0.1 0.0077 16.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 EAQ88958.1 - 5.1e-10 39.4 0.0 6.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ88958.1 - 8.7e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EAQ88958.1 - 3.9e-05 22.9 0.0 7.1e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EAQ88958.1 - 0.033 12.8 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EAQ88958.1 - 0.055 12.4 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase DUF2392 PF10288.4 EAQ88959.1 - 3.6e-17 62.6 0.0 8.7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EAQ88959.1 - 0.0067 15.9 0.1 0.92 8.9 0.0 2.3 2 0 0 2 2 2 2 PP-loop family PAPS_reduct PF01507.14 EAQ88959.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Mito_carr PF00153.22 EAQ88960.1 - 3.3e-59 196.6 0.9 1.8e-20 72.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EAQ88961.1 - 1.5e-16 59.5 2.6 1.3e-08 34.3 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EAQ88961.1 - 0.078 11.0 0.0 0.2 9.7 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SRP9-21 PF05486.7 EAQ88962.1 - 3.7e-25 87.4 0.3 5.5e-25 86.9 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 EAQ88963.1 - 1.8e-120 401.2 1.6 2.2e-120 400.9 1.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mis14 PF08641.7 EAQ88963.1 - 0.0079 16.2 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Fib_succ_major PF09603.5 EAQ88963.1 - 0.12 12.9 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) DUF4112 PF13430.1 EAQ88964.1 - 2.3e-33 114.2 0.1 3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) NUDIX PF00293.23 EAQ88965.1 - 3.1e-15 56.0 0.0 5.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 EAQ88965.1 - 1e-05 25.3 0.6 2.2e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Dcp2, box A domain Hexapep_2 PF14602.1 EAQ88966.1 - 0.069 12.7 0.4 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 EAQ88968.1 - 1.7e-60 204.4 0.0 2.6e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88968.1 - 5.5e-29 101.0 0.0 9.3e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ88968.1 - 0.00013 21.0 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ88968.1 - 0.002 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ88968.1 - 0.03 14.0 0.1 0.03 14.0 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Rtf2 PF04641.7 EAQ88968.1 - 7.1 5.7 10.8 12 4.9 7.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger WD40 PF00400.27 EAQ88969.1 - 4.2e-83 270.5 6.8 1e-15 56.9 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PD40 PF07676.7 EAQ88969.1 - 2.8e-11 42.8 0.2 3.2 7.5 0.0 5.5 5 0 0 5 5 5 5 WD40-like Beta Propeller Repeat NACHT PF05729.7 EAQ88969.1 - 5.5e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ88969.1 - 2.8e-08 33.9 1.2 1.4e-07 31.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain DUF1258 PF06869.7 EAQ88969.1 - 6.7e-07 28.6 0.2 2.8 6.9 0.0 5.2 1 1 4 5 5 5 2 Protein of unknown function (DUF1258) Germane PF10646.4 EAQ88969.1 - 0.00037 20.6 1.1 2 8.5 0.0 4.2 3 1 1 4 4 4 1 Sporulation and spore germination IKI3 PF04762.7 EAQ88969.1 - 0.00053 17.9 0.1 0.92 7.2 0.0 2.7 1 1 0 2 2 2 2 IKI3 family Proteasome_A_N PF10584.4 EAQ88969.1 - 0.00081 18.6 0.4 1.1e+02 2.2 0.0 5.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Replicase PF03090.12 EAQ88969.1 - 0.0017 18.2 0.0 36 4.2 0.0 4.8 1 1 4 5 5 5 0 Replicase family DUF815 PF05673.8 EAQ88969.1 - 0.022 13.7 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EAQ88969.1 - 0.031 13.1 0.0 0.077 11.8 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain DUF948 PF06103.6 EAQ88969.1 - 0.07 12.9 0.2 0.36 10.7 0.2 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_22 PF13401.1 EAQ88969.1 - 0.084 13.0 0.0 0.91 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EAQ88969.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1900 PF08954.6 EAQ88971.1 - 5.1e-49 165.2 0.0 1.9e-47 160.1 0.0 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EAQ88971.1 - 4.2e-34 116.0 0.0 7.9e-34 115.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EAQ88971.1 - 2.2e-24 84.3 4.9 3.1e-07 30.0 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 EAQ88971.1 - 0.0006 19.5 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAQ88971.1 - 0.0018 16.5 0.6 0.048 11.7 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SNARE PF05739.14 EAQ88971.1 - 0.19 11.4 3.9 3.2 7.5 2.7 2.2 1 1 0 1 1 1 0 SNARE domain SlyX PF04102.7 EAQ88971.1 - 0.5 10.7 9.0 0.37 11.1 2.8 2.4 2 0 0 2 2 2 0 SlyX Glyco_transf_22 PF03901.12 EAQ88972.1 - 1.3e-74 251.6 20.6 1.7e-74 251.3 14.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EAQ88973.1 - 8.9e-82 274.6 0.0 6.2e-80 268.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EAQ88973.1 - 0.01 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3543 PF12063.3 EAQ88974.1 - 4.5e-95 317.4 1.0 6.9e-95 316.7 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EAQ88974.1 - 2.1e-60 204.1 0.0 3.6e-60 203.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ88974.1 - 1.7e-39 135.4 0.0 3.7e-39 134.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ88974.1 - 0.043 12.7 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Zeta_toxin PF06414.7 EAQ88975.1 - 0.082 11.9 0.0 12 4.9 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin MFS_1 PF07690.11 EAQ88976.1 - 1e-32 113.2 26.1 1.5e-32 112.7 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RhoGAP PF00620.22 EAQ88977.1 - 1.2e-37 128.8 0.0 2.4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Abhydrolase_2 PF02230.11 EAQ88978.1 - 7.3e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 EAQ88978.1 - 1.7e-05 24.3 0.1 7.1e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EAQ88978.1 - 4.1e-05 22.9 0.1 6.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EAQ88978.1 - 4.1e-05 22.9 1.4 0.00011 21.4 0.1 2.2 2 1 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EAQ88978.1 - 0.00051 19.8 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ88978.1 - 0.0037 17.1 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EAQ88978.1 - 0.048 12.1 0.0 0.069 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SH3_3 PF08239.6 EAQ88979.1 - 0.00012 22.1 0.2 0.00035 20.6 0.1 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain DUF3328 PF11807.3 EAQ88980.1 - 6.2e-32 111.0 0.1 7.8e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) APH PF01636.18 EAQ88981.1 - 8.4e-15 55.1 0.6 2.1e-14 53.8 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ88981.1 - 0.0096 15.5 0.0 0.024 14.2 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase CDC45 PF02724.9 EAQ88981.1 - 0.03 12.3 2.5 0.033 12.2 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EAQ88981.1 - 0.034 12.0 7.5 0.045 11.6 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EAQ88981.1 - 0.13 10.3 4.5 0.19 9.8 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tom37_C PF11801.3 EAQ88981.1 - 0.15 11.9 0.6 0.66 9.8 0.4 1.8 2 0 0 2 2 2 0 Tom37 C-terminal domain DNA_pol_phi PF04931.8 EAQ88981.1 - 0.34 8.6 14.1 0.47 8.1 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.4 EAQ88981.1 - 0.49 9.0 19.8 0.86 8.2 13.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.5 EAQ88981.1 - 0.7 9.8 7.5 0.043 13.8 1.5 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.1 EAQ88981.1 - 1.1 9.2 2.7 2.1 8.3 1.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein CobT PF06213.7 EAQ88981.1 - 2.2 7.3 14.3 4.2 6.4 9.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EAQ88981.1 - 2.6 7.5 13.5 0.071 12.7 5.0 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-Tim10_DDP PF02953.10 EAQ88982.1 - 8.2e-20 69.8 0.7 1.1e-19 69.4 0.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EAQ88982.1 - 0.036 13.5 1.2 0.25 10.7 0.6 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Nup188 PF10487.4 EAQ88983.1 - 9.4e-25 86.7 0.0 1.7e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 EAQ88984.1 - 8.9e-97 323.1 0.0 1.8e-96 322.1 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EAQ88984.1 - 2.7e-50 170.6 0.0 7.3e-46 156.2 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EAQ88984.1 - 5e-50 169.6 0.0 8.1e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAQ88984.1 - 3e-05 23.5 0.2 9.4e-05 21.9 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EAQ88984.1 - 0.095 12.2 0.2 0.68 9.4 0.0 2.4 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain Use1 PF09753.4 EAQ88986.1 - 2e-06 27.4 3.2 3.1e-06 26.8 2.2 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 Tmemb_cc2 PF10267.4 EAQ88986.1 - 0.036 12.6 11.6 0.07 11.6 8.1 1.5 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF605 PF04652.11 EAQ88986.1 - 0.11 11.8 27.7 0.14 11.5 19.2 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EAQ88986.1 - 0.58 8.3 15.4 0.72 8.0 10.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 EAQ88986.1 - 0.72 7.4 8.6 0.51 7.9 4.8 1.4 1 1 1 2 2 2 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 EAQ88986.1 - 2.5 6.8 14.2 3.8 6.2 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Synaptobrevin PF00957.16 EAQ88986.1 - 5.7 6.6 7.0 0.45 10.1 0.2 2.5 3 0 0 3 3 3 0 Synaptobrevin Nucleo_P87 PF07267.6 EAQ88986.1 - 8.2 4.9 13.3 15 4.0 9.2 1.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Methyltransf_28 PF02636.12 EAQ88987.1 - 1.4e-37 129.5 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Lung_7-TM_R PF06814.8 EAQ88988.1 - 6e-53 179.7 14.4 1.7e-42 145.4 8.0 2.1 1 1 1 2 2 2 2 Lung seven transmembrane receptor DUF1673 PF07895.6 EAQ88988.1 - 0.077 12.5 3.6 0.18 11.3 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) PrgI PF12666.2 EAQ88988.1 - 2.3 8.4 13.0 0.15 12.1 1.8 2.8 1 1 1 2 2 2 0 PrgI family protein Pro_isomerase PF00160.16 EAQ88989.1 - 4.2e-43 147.2 0.0 7.6e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EAQ88989.1 - 4.6e-05 23.2 0.0 0.00027 20.8 0.0 2.2 2 0 0 2 2 2 1 U-box domain Fungal_trans_2 PF11951.3 EAQ88990.1 - 2.6e-12 46.0 0.2 2.5e-06 26.3 0.0 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ88990.1 - 3.7e-07 29.9 12.5 8e-07 28.8 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KTI12 PF08433.5 EAQ88991.1 - 1.8e-33 115.9 0.0 8.3e-33 113.7 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 PAT1 PF09770.4 EAQ88991.1 - 2.9 6.0 4.3 3.8 5.6 3.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EAQ88991.1 - 8 5.7 16.3 13 5.0 11.3 1.3 1 0 0 1 1 1 0 Vta1 like DnaJ PF00226.26 EAQ88992.1 - 3.3e-18 65.1 1.5 7.3e-18 64.0 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.11 EAQ88992.1 - 3.9e-18 65.7 0.0 1.8e-12 47.1 0.0 3.0 2 1 0 2 2 2 2 Sec63 Brl domain MFS_1 PF07690.11 EAQ88992.1 - 0.0084 14.8 0.1 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4229 PF14012.1 EAQ88992.1 - 0.017 14.9 0.6 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF4131 PF13567.1 EAQ88992.1 - 0.031 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TPR_11 PF13414.1 EAQ88993.1 - 4.4e-43 144.7 6.8 1e-14 53.9 0.1 5.9 5 2 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 EAQ88993.1 - 3.2e-40 134.1 1.7 8.1e-08 31.5 0.0 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ88993.1 - 6.8e-34 113.0 3.6 7e-07 28.6 0.0 8.5 8 1 1 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.26 EAQ88993.1 - 6.8e-29 99.3 2.3 3e-28 97.3 1.6 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 EAQ88993.1 - 2.6e-25 88.5 6.4 2.1e-08 34.3 0.0 5.7 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ88993.1 - 3.6e-23 81.6 7.5 2.6e-07 31.1 0.0 5.8 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ88993.1 - 5.5e-18 63.3 0.3 0.00032 20.2 0.0 6.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ88993.1 - 1.8e-17 62.2 9.4 3.5e-05 24.0 0.0 8.1 6 3 4 10 10 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ88993.1 - 2.2e-17 61.4 0.1 0.09 12.6 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ88993.1 - 3.8e-16 58.7 4.2 0.021 14.7 0.0 6.2 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ88993.1 - 4.4e-13 48.3 7.7 0.00033 20.6 0.0 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EAQ88993.1 - 2.5e-12 46.7 0.4 0.02 15.0 0.0 4.8 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAQ88993.1 - 1.3e-10 40.9 6.5 0.03 14.7 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ88993.1 - 5.4e-10 38.9 8.6 0.018 14.9 0.1 4.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EAQ88993.1 - 1.5e-06 27.4 4.1 0.032 13.2 0.1 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAQ88993.1 - 2e-05 24.3 1.8 7.9 6.4 0.1 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EAQ88993.1 - 9.7e-05 22.1 0.5 2.6 8.1 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EAQ88993.1 - 0.00025 20.2 0.2 0.48 9.6 0.0 3.1 2 0 0 2 2 2 2 SHNi-TPR TPR_4 PF07721.9 EAQ88993.1 - 0.0012 19.1 0.8 0.93 10.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 EAQ88993.1 - 0.0027 18.0 1.6 53 4.0 0.0 4.4 3 1 0 3 3 3 0 Bacterial transcriptional activator domain NARP1 PF12569.3 EAQ88993.1 - 0.003 16.3 1.7 0.29 9.8 0.4 3.2 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 MIT PF04212.13 EAQ88993.1 - 0.003 17.3 0.2 4.5 7.2 0.0 4.2 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EAQ88993.1 - 0.0085 16.0 4.2 3.3 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EAQ88993.1 - 0.043 13.9 7.2 2.8 8.1 0.0 4.0 2 1 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EAQ88993.1 - 0.069 12.3 0.3 4.5 6.3 0.1 2.8 3 1 0 3 3 3 0 Coatomer epsilon subunit RRM_3 PF08777.6 EAQ88993.1 - 0.12 12.2 1.2 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif EF-hand_6 PF13405.1 EAQ88994.1 - 4.7e-07 29.1 0.0 1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EAQ88994.1 - 2.4e-05 23.3 0.1 4.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EAQ88994.1 - 2.6e-05 23.3 0.6 4.5e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EAQ88994.1 - 0.00076 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 EAQ88994.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 EAQ88994.1 - 0.097 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair Afi1 PF07792.7 EAQ88995.1 - 3.1e-64 215.3 0.0 5.9e-64 214.4 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EAQ88995.1 - 6.2e-38 128.9 0.0 1.3e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EAQ88995.1 - 7.2e-08 31.3 0.0 0.017 13.6 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EAQ88995.1 - 0.012 14.9 0.0 0.065 12.4 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Esterase PF00756.15 EAQ88996.1 - 1.3e-49 168.9 0.0 1.5e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EAQ88996.1 - 0.00023 20.4 0.2 0.0016 17.7 0.1 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EAQ88996.1 - 0.00036 20.2 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ88996.1 - 0.00062 19.7 0.1 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ88996.1 - 0.033 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NACHT PF05729.7 EAQ88998.1 - 2e-08 34.0 0.2 0.0035 17.0 0.0 2.8 3 0 0 3 3 2 2 NACHT domain ABC_tran PF00005.22 EAQ88998.1 - 0.0048 17.2 0.2 0.015 15.6 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EAQ88998.1 - 0.0079 16.3 0.1 0.34 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAQ88998.1 - 0.01 16.1 0.0 0.038 14.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAQ88998.1 - 0.018 13.9 0.0 0.092 11.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Ank_2 PF12796.2 EAQ88998.1 - 0.023 15.0 0.0 0.11 12.8 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Abhydrolase_6 PF12697.2 EAQ88998.1 - 0.024 14.5 0.1 0.091 12.6 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EAQ88998.1 - 0.028 13.7 0.1 0.058 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Trans_reg_C PF00486.23 EAQ88998.1 - 0.028 14.3 0.4 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal AAA_16 PF13191.1 EAQ88998.1 - 0.041 13.8 2.7 1.6 8.6 1.9 2.5 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EAQ88998.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Ank PF00023.25 EAQ88998.1 - 0.073 12.9 0.0 4.5 7.2 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat AAA_17 PF13207.1 EAQ88998.1 - 0.075 13.8 0.0 0.32 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ88998.1 - 0.12 12.0 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EAQ88998.1 - 0.13 11.5 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PGAP1 PF07819.8 EAQ88998.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AAA_10 PF12846.2 EAQ88998.1 - 0.22 10.9 0.5 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EAQ88998.1 - 0.27 11.5 0.6 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain YscO PF07321.7 EAQ88998.1 - 0.41 10.4 5.2 0.94 9.2 3.6 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO GARS_A PF01071.14 EAQ89001.1 - 5.3e-82 274.1 0.0 7.7e-82 273.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EAQ89001.1 - 3.4e-35 120.5 0.1 1.4e-34 118.4 0.0 2.2 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EAQ89001.1 - 3.5e-32 111.5 0.2 7.6e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EAQ89001.1 - 1.2e-28 99.0 0.0 3.1e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EAQ89001.1 - 1.3e-15 57.3 3.1 4.1e-15 55.8 1.1 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EAQ89001.1 - 2e-08 34.2 0.0 6.5e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EAQ89001.1 - 2.2e-08 33.2 0.0 1.3e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EAQ89001.1 - 4.9e-05 22.7 0.0 9.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EAQ89001.1 - 0.00036 19.9 0.0 0.00065 19.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EAQ89001.1 - 0.053 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.9 EAQ89001.1 - 0.08 12.8 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Acyltransferase PF01553.16 EAQ89002.1 - 3.3e-32 110.7 0.0 5e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2347 PF09804.4 EAQ89003.1 - 1.2e-54 185.5 0.0 1.5e-46 158.9 0.0 2.5 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EAQ89003.1 - 1.7e-42 145.5 0.0 1.2e-41 142.7 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 EAQ89003.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis WD40 PF00400.27 EAQ89004.1 - 2.2e-67 220.6 15.2 1.5e-10 40.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EAQ89004.1 - 1.2e-26 92.7 8.0 1.8e-26 92.1 5.5 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EAQ89004.1 - 0.00015 20.0 2.9 0.61 8.1 0.6 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ89004.1 - 0.0023 16.7 0.1 1.7 7.2 0.0 3.4 1 1 4 5 5 5 2 Nup133 N terminal like LXG PF04740.7 EAQ89004.1 - 0.057 13.2 1.8 0.08 12.7 1.2 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Cytochrom_D1 PF02239.11 EAQ89004.1 - 0.06 11.6 0.1 2 6.6 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.1 EAQ89004.1 - 0.072 12.1 0.1 11 4.9 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EAQ89004.1 - 0.12 10.1 0.0 0.18 9.5 0.0 1.2 1 0 0 1 1 1 0 IKI3 family DUF3328 PF11807.3 EAQ89005.1 - 5.6e-36 124.2 0.1 7.2e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1296 PF06972.6 EAQ89005.1 - 0.096 12.6 0.1 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF2015 PF09435.5 EAQ89006.1 - 3.6e-52 175.5 0.0 4e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EAQ89008.1 - 3.1e-37 127.5 0.9 4.1e-37 127.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.13 EAQ89010.1 - 3.5e-45 153.8 0.0 5.2e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EAQ89010.1 - 1.7e-42 144.5 0.1 2.4e-42 144.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EAQ89010.1 - 0.0016 17.1 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EAQ89010.1 - 0.071 12.4 0.1 2.4 7.4 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EAQ89011.1 - 9.9e-39 132.2 0.0 2.7e-26 91.9 0.0 2.0 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component PINIT PF14324.1 EAQ89012.1 - 4.5e-47 159.7 0.0 6.9e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EAQ89012.1 - 2.2e-22 78.2 5.1 3.8e-22 77.5 3.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EAQ89012.1 - 2.7e-05 23.5 0.0 5.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EAQ89012.1 - 6.4e-05 22.3 1.4 0.00013 21.4 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 EAQ89012.1 - 0.044 13.3 0.1 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 EAQ89012.1 - 0.15 11.9 4.7 0.31 10.9 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EAQ89012.1 - 0.48 10.1 3.0 0.91 9.3 2.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2423 PF10338.4 EAQ89013.1 - 8.2e-16 57.7 5.9 1.4e-15 56.9 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.17 EAQ89013.1 - 0.0011 18.3 0.1 1.2 8.3 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAQ89013.1 - 0.014 14.5 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 Sulfatase Cnd3 PF12719.2 EAQ89014.1 - 2.1e-75 253.4 0.2 2.6e-73 246.6 0.0 3.0 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EAQ89014.1 - 2e-08 34.4 4.3 0.001 19.2 0.2 4.3 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EAQ89014.1 - 0.00013 21.7 2.6 0.17 12.0 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat DUF1546 PF07571.8 EAQ89014.1 - 0.021 14.9 0.6 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Tom37_C PF11801.3 EAQ89014.1 - 0.27 11.0 1.3 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain RRM_1 PF00076.17 EAQ89015.1 - 5.1e-61 202.2 0.2 1.2e-18 66.4 0.0 6.1 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89015.1 - 1.5e-42 143.4 0.3 6.2e-12 45.3 0.0 5.7 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89015.1 - 1.1e-22 79.6 0.1 2.5e-08 33.6 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neur_chan_memb PF02932.11 EAQ89015.1 - 8.7 6.1 5.4 12 5.6 1.9 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF934 PF06073.7 EAQ89016.1 - 0.022 14.4 0.1 0.7 9.6 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF934) DUF4376 PF14301.1 EAQ89016.1 - 0.047 13.8 0.2 0.68 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Mg_trans_NIPA PF05653.9 EAQ89017.1 - 5.9e-62 209.3 8.9 3.1e-59 200.3 4.0 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EAQ89017.1 - 0.0014 18.7 0.4 0.0014 18.7 0.3 4.4 4 1 1 5 5 5 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EAQ89017.1 - 0.011 14.5 4.0 1.5 7.5 0.9 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) F-box PF00646.28 EAQ89017.1 - 0.049 13.2 0.5 0.13 11.9 0.3 1.8 1 0 0 1 1 1 0 F-box domain YfhO PF09586.5 EAQ89017.1 - 0.52 8.2 7.2 0.78 7.6 5.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Col_cuticle_N PF01484.12 EAQ89017.1 - 0.58 9.8 3.3 35 4.1 0.1 3.8 4 0 0 4 4 4 0 Nematode cuticle collagen N-terminal domain EamA PF00892.15 EAQ89017.1 - 0.88 9.6 25.7 0.075 13.0 2.1 3.9 3 1 0 3 3 3 0 EamA-like transporter family SVM_signal PF12113.3 EAQ89017.1 - 8.7 6.2 6.1 0.78 9.6 0.6 2.0 2 0 0 2 2 2 0 SVM protein signal sequence Erf4 PF10256.4 EAQ89020.1 - 1.3e-31 108.8 0.0 1.8e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family AMP-binding PF00501.23 EAQ89021.1 - 9.1e-29 100.0 0.0 1.4e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ89021.1 - 1.9e-17 63.9 0.3 3.8e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HNH_2 PF13391.1 EAQ89022.1 - 3.5e-05 23.4 0.1 8.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_1 PF00232.13 EAQ89023.1 - 2.2e-150 500.8 0.1 2.7e-150 500.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SSrecog PF03531.9 EAQ89026.1 - 9.9e-51 172.1 0.2 2.2e-49 167.8 0.2 2.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EAQ89026.1 - 5.8e-25 87.0 0.1 3.7e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 EAQ89026.1 - 0.81 8.8 0.0 0.81 8.8 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Xpo1 PF08389.7 EAQ89027.1 - 3.5e-40 137.3 0.8 1e-38 132.5 0.0 3.4 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 EAQ89027.1 - 0.00014 21.6 1.7 0.6 10.3 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat INTS5_C PF14838.1 EAQ89027.1 - 0.031 12.5 0.3 0.19 9.9 0.0 2.1 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus Peptidase_M18 PF02127.10 EAQ89029.1 - 1.4e-171 570.8 0.0 1.5e-171 570.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EAQ89029.1 - 4.8e-05 22.2 0.0 0.001 17.9 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Whi5 PF08528.6 EAQ89032.1 - 5.4e-10 38.6 0.0 9.1e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Miff PF05644.6 EAQ89032.1 - 3.7 7.0 14.6 0.62 9.6 1.6 2.5 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff NRDE-2 PF08424.5 EAQ89033.1 - 8.7e-87 290.9 0.0 8.2e-86 287.7 0.0 2.3 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference Voltage_CLC PF00654.15 EAQ89034.1 - 2.8e-93 312.7 19.3 3.7e-93 312.3 13.4 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel TAT_signal PF10518.4 EAQ89034.1 - 0.011 15.6 3.4 0.011 15.6 2.4 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Cation_efflux PF01545.16 EAQ89035.1 - 8.2e-54 182.5 0.2 1e-53 182.2 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EAQ89035.1 - 0.014 14.4 14.1 0.079 11.9 9.8 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter PAP2 PF01569.16 EAQ89035.1 - 0.28 10.8 7.2 0.65 9.6 1.8 2.5 1 1 2 3 3 3 0 PAP2 superfamily SIR2 PF02146.12 EAQ89036.1 - 2e-28 99.3 0.0 2.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Peptidase_C50 PF03568.12 EAQ89037.1 - 7.6e-113 377.0 0.0 1.2e-112 376.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EAQ89037.1 - 0.0037 17.1 0.5 0.0037 17.1 0.3 7.5 7 2 1 8 8 8 3 Tetratricopeptide repeat Glyco_hydro_7 PF00840.15 EAQ89038.1 - 1.9e-123 412.0 9.5 2.4e-123 411.7 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Ank_4 PF13637.1 EAQ89039.1 - 0.027 14.9 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ89039.1 - 0.028 14.7 0.1 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) DUF327 PF03885.8 EAQ89039.1 - 0.068 12.9 1.8 0.14 11.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Melibiase PF02065.13 EAQ89041.1 - 9.3e-22 77.2 0.1 2.2e-14 52.9 0.0 2.6 2 1 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 EAQ89041.1 - 0.0047 16.0 0.0 0.0093 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase 97 Glyco_hyd_65N_2 PF14498.1 EAQ89042.1 - 4.9e-52 176.9 0.3 7.4e-52 176.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Peptidase_M7 PF02031.11 EAQ89043.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Zn_clus PF00172.13 EAQ89044.1 - 8.4e-08 32.0 11.3 1.4e-07 31.2 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC92 PF14916.1 EAQ89044.1 - 0.022 14.3 0.6 0.048 13.2 0.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Pox_A_type_inc PF04508.7 EAQ89044.1 - 0.12 12.2 4.7 0.25 11.1 3.3 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ADH_N PF08240.7 EAQ89045.1 - 5.3e-23 80.8 1.0 9.7e-23 80.0 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ89045.1 - 2e-16 59.7 0.0 3.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ89045.1 - 0.00011 23.0 0.0 0.0002 22.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EAQ89045.1 - 0.00025 20.2 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EAQ89045.1 - 0.005 16.4 1.2 0.0067 16.0 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_35 PF01301.14 EAQ89046.1 - 2.2e-87 293.4 0.0 2.6e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 EAQ89046.1 - 3.9e-09 36.1 0.4 1.9e-08 33.8 0.3 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 EAQ89046.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain POP1 PF06978.6 EAQ89049.1 - 0.22 11.1 2.1 0.42 10.2 1.4 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Zn_clus PF00172.13 EAQ89051.1 - 4.9e-10 39.1 10.8 8.1e-10 38.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ89052.1 - 3.9e-12 45.5 0.0 1.4e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Kri1_C PF12936.2 EAQ89053.1 - 1.1e-26 92.6 0.1 1.1e-26 92.6 0.1 4.6 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.7 EAQ89053.1 - 2.2e-25 88.8 25.6 2.2e-25 88.8 17.7 6.2 6 2 1 7 7 7 1 KRI1-like family Mig-14 PF07395.6 EAQ89053.1 - 1.7 7.5 9.5 2.6 6.9 0.4 2.3 2 0 0 2 2 2 0 Mig-14 Ras PF00071.17 EAQ89054.1 - 4.4e-58 195.2 0.0 5e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ89054.1 - 2.4e-20 73.2 0.0 3.6e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ89054.1 - 8.8e-14 51.1 0.0 1.5e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ89054.1 - 2.4e-06 27.1 0.0 6.2e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ89054.1 - 6.5e-06 25.4 0.0 8.3e-06 25.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ89054.1 - 8.3e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EAQ89054.1 - 0.0078 16.2 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ89054.1 - 0.045 13.8 0.0 0.16 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain BUD22 PF09073.5 EAQ89056.1 - 7.8 5.4 8.8 9.9 5.1 6.1 1.3 1 0 0 1 1 1 0 BUD22 GCV_T PF01571.16 EAQ89057.1 - 8.7e-15 54.6 0.2 2.2e-13 50.0 0.0 2.7 2 1 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EAQ89057.1 - 0.0031 17.5 0.1 0.0067 16.4 0.1 1.6 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 EAQ89058.1 - 4.2e-12 45.6 0.3 2.1e-11 43.3 0.2 2.3 1 0 0 1 1 1 1 DnaJ domain Pol_alpha_B_N PF08418.5 EAQ89058.1 - 5.9 6.3 18.7 0.26 10.7 7.1 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF966 PF06136.8 EAQ89058.1 - 6 6.1 11.7 8.4 5.7 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CorA PF01544.13 EAQ89059.1 - 8.1e-14 51.3 0.0 1.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DIOX_N PF14226.1 EAQ89060.1 - 7e-22 78.1 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAQ89060.1 - 1.4e-16 60.6 0.0 2.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Helicase_C PF00271.26 EAQ89062.1 - 3.3e-27 94.1 0.1 8.5e-27 92.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ89062.1 - 2.3e-09 36.9 0.0 5.2e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase CDC45 PF02724.9 EAQ89062.1 - 0.02 12.9 5.4 0.028 12.4 3.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EAQ89062.1 - 4.7 5.0 11.6 6.4 4.5 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EAQ89063.1 - 9.2e-60 201.9 0.0 1.1e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89063.1 - 1.4e-34 119.3 0.0 1.8e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89063.1 - 1.9e-08 33.5 0.0 2.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EAQ89063.1 - 0.29 9.9 0.1 0.43 9.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 TruD PF01142.13 EAQ89064.1 - 2.5e-55 187.6 0.0 6.4e-51 173.1 0.0 3.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) DUF4518 PF15008.1 EAQ89064.1 - 0.065 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF1804 PF08822.6 EAQ89064.1 - 0.08 12.6 2.6 0.12 12.0 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1804) CH PF00307.26 EAQ89065.1 - 8.6e-39 131.9 0.1 2.9e-19 69.0 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EAQ89065.1 - 5.2e-26 90.4 0.0 2.5e-25 88.2 0.0 2.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EAQ89065.1 - 8.2e-13 47.8 0.6 2.5e-07 30.2 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.16 EAQ89065.1 - 8.1e-06 26.0 3.2 0.002 18.3 0.9 2.6 2 0 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.1 EAQ89065.1 - 0.00012 21.6 0.3 0.0012 18.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EAQ89065.1 - 0.0043 16.6 1.0 0.033 13.7 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EAQ89065.1 - 0.0045 16.1 0.4 0.037 13.3 0.0 2.6 2 0 0 2 2 2 1 EF hand DUF1943 PF09172.6 EAQ89065.1 - 0.047 12.5 0.1 0.084 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) EF-hand_7 PF13499.1 EAQ89065.1 - 0.15 12.2 4.0 0.21 11.7 1.3 2.5 2 0 0 2 2 2 0 EF-hand domain pair VPS9 PF02204.13 EAQ89066.1 - 1.6e-26 92.3 0.1 3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain K_oxygenase PF13434.1 EAQ89066.1 - 0.079 11.8 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) MRFAP1 PF15155.1 EAQ89067.1 - 0.0031 17.8 11.3 0.0047 17.2 7.9 1.2 1 0 0 1 1 1 1 MORF4 family-associated protein1 ATP-synt_B PF00430.13 EAQ89067.1 - 0.54 10.0 11.3 0.89 9.3 7.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) V-ATPase_G PF03179.10 EAQ89067.1 - 0.97 9.7 12.0 2.1 8.7 8.3 1.5 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mnd1 PF03962.10 EAQ89067.1 - 5.7 6.5 7.1 8.4 6.0 4.9 1.1 1 0 0 1 1 1 0 Mnd1 family Lipase_3 PF01764.20 EAQ89068.1 - 1.9e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EAQ89068.1 - 0.011 15.4 0.1 0.025 14.3 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EAQ89068.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C3HC4 PF00097.20 EAQ89069.1 - 2.5e-07 30.2 4.1 2.5e-07 30.2 2.8 5.2 6 2 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ89069.1 - 8.3e-06 25.7 3.3 8.3e-06 25.7 2.3 4.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EAQ89069.1 - 1.8e-05 24.4 0.4 1.8e-05 24.4 0.2 3.1 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EAQ89069.1 - 0.00012 21.8 5.1 0.00012 21.8 3.6 4.3 4 3 0 4 4 4 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.23 EAQ89069.1 - 0.0036 16.6 0.3 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 SH3 domain zf-RING_UBOX PF13445.1 EAQ89069.1 - 0.0059 16.2 3.4 0.018 14.7 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger SH3_9 PF14604.1 EAQ89069.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.4 2 0 0 2 2 2 0 Variant SH3 domain ECH PF00378.15 EAQ89070.1 - 2.8e-65 219.8 0.2 3.4e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EAQ89070.1 - 0.029 14.5 0.1 0.16 12.0 0.0 2.1 2 1 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 EAQ89071.1 - 9.5e-81 269.5 7.0 1.1e-80 269.4 4.8 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.8 EAQ89072.1 - 7.8e-15 54.5 0.0 7.8e-15 54.5 0.0 3.3 3 1 0 3 3 3 1 Paf1 DUF605 PF04652.11 EAQ89073.1 - 0.11 11.8 14.0 0.23 10.8 9.7 1.4 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 EAQ89073.1 - 0.12 12.3 9.3 0.28 11.2 6.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_transf_90 PF05686.7 EAQ89073.1 - 0.12 10.9 9.3 0.65 8.6 0.1 3.5 3 1 0 3 3 3 0 Glycosyl transferase family 90 Pox_P35 PF03213.9 EAQ89073.1 - 0.44 9.4 1.0 0.79 8.6 0.7 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein RR_TM4-6 PF06459.7 EAQ89073.1 - 1.1 9.0 4.8 1.8 8.3 3.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2360 PF10152.4 EAQ89073.1 - 1.7 8.9 10.0 3.3 8.0 6.4 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 EAQ89073.1 - 2.4 6.2 19.1 3.4 5.7 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_S8 PF00410.14 EAQ89074.1 - 2.1e-24 85.7 0.0 2.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.21 EAQ89075.1 - 8.4e-29 98.9 0.7 1e-28 98.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EAQ89075.1 - 0.063 12.8 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Rotamase_3 PF13616.1 EAQ89076.1 - 0.00027 21.1 0.5 0.00049 20.3 0.1 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EAQ89076.1 - 0.039 14.6 0.1 0.039 14.6 0.1 2.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain Mtf2_C PF14061.1 EAQ89076.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Cytomega_UL84 PF06284.6 EAQ89076.1 - 0.083 11.2 0.1 0.12 10.7 0.0 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL84 protein Neurochondrin PF05536.6 EAQ89078.1 - 1.6e-67 228.0 0.0 1.4e-66 224.9 0.0 1.9 1 1 0 1 1 1 1 Neurochondrin SSP160 PF06933.6 EAQ89078.1 - 2.6e-05 22.4 10.0 2.8e-05 22.3 3.0 2.2 2 0 0 2 2 2 2 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EAQ89078.1 - 1.5 8.5 19.3 0.31 10.7 9.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Voltage_CLC PF00654.15 EAQ89079.1 - 5.4e-55 186.8 19.5 2.6e-54 184.6 14.3 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EAQ89079.1 - 3.1e-05 23.6 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain TCTP PF00838.12 EAQ89080.1 - 9e-66 220.9 4.4 1e-65 220.7 3.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.8 EAQ89081.1 - 0.029 14.7 2.3 0.029 14.7 1.6 2.4 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily PPR_2 PF13041.1 EAQ89083.1 - 5.9e-20 70.9 0.0 1.8e-06 27.8 0.0 6.2 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EAQ89083.1 - 2.9e-16 58.3 0.8 0.026 14.7 0.0 7.1 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.15 EAQ89083.1 - 2.1e-11 43.0 0.1 0.012 15.5 0.0 6.5 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 EAQ89083.1 - 1.3e-05 24.5 1.0 0.14 11.6 0.0 4.9 5 0 0 5 5 5 2 PPR repeat His_Phos_2 PF00328.17 EAQ89084.1 - 1.8e-24 86.7 0.0 1.9e-23 83.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AATF-Che1 PF13339.1 EAQ89085.1 - 0.013 15.6 0.6 1.5 8.9 0.6 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor OPA3 PF07047.7 EAQ89085.1 - 0.014 15.1 1.3 0.022 14.5 0.9 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Ras PF00071.17 EAQ89087.1 - 2.1e-51 173.5 0.0 2.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ89087.1 - 2.7e-15 56.9 0.0 4.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ89087.1 - 1.2e-05 24.6 0.0 1.5e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family tRNA-synt_2 PF00152.15 EAQ89088.1 - 6.9e-41 140.1 0.6 7.7e-40 136.6 0.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) RRM_6 PF14259.1 EAQ89090.1 - 2.2e-39 133.2 0.0 3.9e-11 42.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ89090.1 - 1.6e-37 126.9 0.1 1.2e-11 44.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89090.1 - 2.6e-20 72.0 0.1 4.2e-05 23.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EAQ89090.1 - 6.5e-13 48.0 4.6 6.5e-13 48.0 3.2 2.7 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EAQ89090.1 - 0.00024 20.8 0.1 0.034 13.9 0.1 2.7 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 EAQ89090.1 - 0.075 13.0 0.0 0.56 10.2 0.0 2.5 3 0 0 3 3 3 0 RNA binding domain Mis12 PF05859.7 EAQ89091.1 - 1.1e-31 109.5 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein YL1 PF05764.8 EAQ89092.1 - 4.2e-40 137.8 48.9 1.5e-24 86.9 13.1 3.5 3 1 1 4 4 4 2 YL1 nuclear protein YL1_C PF08265.6 EAQ89092.1 - 2.6e-14 52.4 1.6 4.3e-14 51.7 1.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 EAQ89092.1 - 0.046 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger PALP PF00291.20 EAQ89093.1 - 2e-62 211.2 0.4 2.4e-62 210.9 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SipA PF09052.5 EAQ89093.1 - 0.17 10.2 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A Ribosomal_L19 PF01245.15 EAQ89095.1 - 4.8e-19 68.2 0.1 9e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 TrkH PF02386.11 EAQ89096.1 - 6.4e-94 314.4 15.5 6e-86 288.2 2.4 3.1 2 1 1 3 3 3 3 Cation transport protein Helicase_C_3 PF13625.1 EAQ89097.1 - 7.1e-25 87.2 0.0 4e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ89097.1 - 5e-12 46.0 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAQ89097.1 - 1.2e-11 44.2 0.0 3.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAQ89097.1 - 1e-08 34.3 0.0 1.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CHY PF05495.7 EAQ89098.1 - 3e-09 36.8 8.9 4.1e-09 36.4 6.1 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EAQ89098.1 - 0.0047 16.7 8.5 0.057 13.2 3.5 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DUF3797 PF12677.2 EAQ89098.1 - 0.014 14.9 2.4 0.85 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zinc_ribbon_5 PF13719.1 EAQ89098.1 - 0.24 11.0 11.9 10 5.8 0.1 3.8 3 1 1 4 4 4 0 zinc-ribbon domain Cytochrome_C7 PF14522.1 EAQ89098.1 - 0.24 11.0 9.2 0.41 10.3 6.4 1.3 1 0 0 1 1 1 0 Cytochrome c7 zinc_ribbon_4 PF13717.1 EAQ89098.1 - 0.24 11.1 12.3 11 5.8 0.1 3.8 3 1 1 4 4 4 0 zinc-ribbon domain RNHCP PF12647.2 EAQ89098.1 - 0.69 9.7 5.9 0.18 11.6 0.7 2.1 2 0 0 2 2 2 0 RNHCP domain zf-TFIIB PF13453.1 EAQ89098.1 - 0.71 9.1 6.4 14 4.9 0.0 2.6 2 1 0 2 2 2 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.5 EAQ89098.1 - 0.73 9.8 12.6 6.8 6.7 5.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 EAQ89098.1 - 0.94 9.1 9.2 0.5 10.0 3.1 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Terminase_GpA PF05876.7 EAQ89098.1 - 1.1 7.5 6.2 1.5 7.0 4.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) C1_4 PF07975.7 EAQ89098.1 - 1.2 9.1 11.1 7.7 6.6 5.1 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain zf-RING_3 PF14369.1 EAQ89098.1 - 1.2 9.1 12.9 1.9 8.5 4.8 2.8 2 1 1 3 3 3 0 zinc-finger zf-ribbon_3 PF13248.1 EAQ89098.1 - 1.2 8.4 10.2 7.9 5.8 1.4 2.5 1 1 1 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.1 EAQ89098.1 - 1.6 8.6 7.7 4.6 7.1 0.5 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Elf1 PF05129.8 EAQ89098.1 - 2 8.1 8.2 13 5.5 6.0 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Evr1_Alr PF04777.8 EAQ89098.1 - 3.8 7.4 9.8 29 4.6 6.9 2.2 1 1 1 2 2 2 0 Erv1 / Alr family DZR PF12773.2 EAQ89098.1 - 4.4 7.2 11.6 35 4.3 8.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EAQ89098.1 - 4.5 6.8 10.8 2 7.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Proteasome PF00227.21 EAQ89099.1 - 3.4e-53 179.7 0.1 4.1e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAD-oxidase_C PF02913.14 EAQ89100.1 - 1.8e-60 204.3 0.0 2.7e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAQ89100.1 - 2.6e-37 127.3 0.2 4.6e-37 126.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Innate_immun PF12782.2 EAQ89102.1 - 0.53 9.4 4.2 0.95 8.6 2.9 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DNA_ligase_A_M PF01068.16 EAQ89104.1 - 5.8e-52 176.0 1.6 7.6e-50 169.0 1.1 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAQ89104.1 - 2e-51 174.3 0.0 5.4e-51 172.9 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EAQ89104.1 - 6.6e-28 96.9 0.2 3e-27 94.8 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Myc_N PF01056.13 EAQ89104.1 - 1.2 8.1 27.2 0.93 8.5 8.4 2.4 2 0 0 2 2 2 0 Myc amino-terminal region E1_dh PF00676.15 EAQ89105.1 - 3.1e-114 380.7 0.2 3.7e-114 380.4 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EAQ89105.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.16 EAQ89105.1 - 0.039 13.1 0.2 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Beta-eliminating lyase WD40 PF00400.27 EAQ89106.1 - 8.9e-51 168.0 21.6 1.6e-10 40.4 0.3 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EAQ89106.1 - 1.4e-12 47.1 0.8 2.7e-12 46.2 0.5 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EAQ89106.1 - 6.3e-09 34.5 12.4 0.025 12.7 0.2 5.6 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EAQ89106.1 - 1.3e-05 24.6 1.6 2.5e-05 23.8 1.1 1.5 1 0 0 1 1 1 1 F-box domain CAP_N PF01213.14 EAQ89106.1 - 0.38 9.9 1.6 0.98 8.6 1.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PQQ_3 PF13570.1 EAQ89106.1 - 0.4 11.0 9.0 13 6.1 0.1 5.4 5 1 1 6 6 6 0 PQQ-like domain Zip PF02535.17 EAQ89107.1 - 3.2e-35 121.6 8.7 3.4e-34 118.3 6.1 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Hat1_N PF10394.4 EAQ89108.1 - 7e-42 143.2 0.0 1.5e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus GIDA_assoc_3 PF13932.1 EAQ89108.1 - 0.026 14.5 0.2 0.071 13.1 0.2 1.7 1 0 0 1 1 1 0 GidA associated domain 3 Acetyltransf_1 PF00583.19 EAQ89108.1 - 0.065 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ROKNT PF08067.6 EAQ89108.1 - 0.099 12.5 1.2 0.2 11.5 0.9 1.5 1 0 0 1 1 1 0 ROKNT (NUC014) domain Acetyltransf_7 PF13508.1 EAQ89108.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain P5CR_dimer PF14748.1 EAQ89109.1 - 2.8e-34 117.3 1.8 4.3e-34 116.7 0.4 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EAQ89109.1 - 5.3e-16 58.8 1.7 5.8e-13 49.0 0.1 2.7 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 EAQ89109.1 - 0.02 13.7 0.1 0.11 11.3 0.2 1.8 2 0 0 2 2 2 0 Prephenate dehydrogenase ApbA PF02558.11 EAQ89109.1 - 0.036 13.4 0.1 0.036 13.4 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EAQ89109.1 - 0.16 11.6 5.4 0.69 9.6 3.8 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CTK3 PF12243.3 EAQ89110.1 - 5.1e-25 87.7 1.5 3.3e-23 81.8 0.1 2.2 1 1 1 2 2 2 2 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EAQ89110.1 - 1.5e-20 73.0 13.2 3.9e-20 71.6 9.2 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Ribosomal_L12 PF00542.14 EAQ89111.1 - 8.7e-20 70.5 4.9 1.4e-18 66.6 2.5 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain EIIBC-GUT_N PF03612.9 EAQ89111.1 - 0.03 13.9 0.0 0.63 9.6 0.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_5 PF07728.9 EAQ89112.1 - 6.4e-126 414.7 0.0 1.1e-21 77.0 0.0 9.6 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ89112.1 - 1.6e-30 106.4 14.5 4.3e-05 23.5 0.1 8.2 6 2 0 6 6 6 5 AAA ATPase domain AAA PF00004.24 EAQ89112.1 - 1.3e-28 99.8 0.2 4e-05 23.8 0.0 7.5 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EAQ89112.1 - 6.1e-28 97.0 0.0 8.8e-10 38.2 0.0 7.0 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAQ89112.1 - 1.7e-25 90.2 3.8 0.0024 18.6 0.0 8.3 7 1 0 7 7 6 6 AAA domain AAA_22 PF13401.1 EAQ89112.1 - 4.3e-24 85.1 4.2 0.0054 16.8 0.0 8.6 8 1 0 8 8 6 6 AAA domain AAA_33 PF13671.1 EAQ89112.1 - 7.7e-24 84.2 0.1 0.0027 17.5 0.0 8.1 7 0 0 7 7 7 4 AAA domain AAA_14 PF13173.1 EAQ89112.1 - 1.1e-21 77.0 0.0 0.00021 21.2 0.0 7.9 8 0 0 8 8 7 4 AAA domain AAA_18 PF13238.1 EAQ89112.1 - 9.5e-21 74.4 0.2 0.016 15.5 0.0 7.2 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 EAQ89112.1 - 4.2e-20 71.8 0.1 0.0089 15.5 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain ABC_tran PF00005.22 EAQ89112.1 - 3.2e-19 69.5 10.4 0.0054 17.0 0.0 8.2 8 0 0 8 8 7 4 ABC transporter Sigma54_activ_2 PF14532.1 EAQ89112.1 - 9.3e-19 67.8 1.4 0.00013 22.0 0.0 7.2 7 0 0 7 7 6 3 Sigma-54 interaction domain T2SE PF00437.15 EAQ89112.1 - 4.7e-17 61.7 3.2 0.009 14.9 0.0 6.4 6 0 0 6 6 6 4 Type II/IV secretion system protein DUF258 PF03193.11 EAQ89112.1 - 4.5e-16 58.4 3.8 0.019 14.1 0.1 6.5 6 0 0 6 6 6 5 Protein of unknown function, DUF258 NACHT PF05729.7 EAQ89112.1 - 8.6e-15 54.7 3.4 0.11 12.2 0.0 6.9 7 0 0 7 7 6 4 NACHT domain AAA_29 PF13555.1 EAQ89112.1 - 2e-14 52.8 0.4 0.00089 18.7 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_19 PF13245.1 EAQ89112.1 - 2.9e-14 52.5 4.3 0.015 15.0 0.2 6.7 6 0 0 6 6 6 3 Part of AAA domain Arch_ATPase PF01637.13 EAQ89112.1 - 5.5e-14 52.4 0.2 0.0066 16.1 0.0 6.5 6 0 0 6 6 6 3 Archaeal ATPase Zeta_toxin PF06414.7 EAQ89112.1 - 9.8e-14 50.9 4.1 0.1 11.6 0.0 7.4 8 0 0 8 8 7 3 Zeta toxin RNA_helicase PF00910.17 EAQ89112.1 - 1.4e-13 50.9 0.4 1.2 9.3 0.0 6.9 6 0 0 6 6 6 1 RNA helicase MobB PF03205.9 EAQ89112.1 - 3.4e-13 49.5 0.9 0.63 9.7 0.0 6.7 6 0 0 6 6 6 4 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EAQ89112.1 - 1.2e-11 44.3 5.4 0.017 14.7 0.0 5.7 6 0 0 6 6 5 3 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EAQ89112.1 - 1.2e-11 44.3 1.1 0.33 10.3 0.0 7.2 7 0 0 7 7 7 2 IstB-like ATP binding protein AAA_25 PF13481.1 EAQ89112.1 - 2.1e-11 43.6 0.3 0.67 9.3 0.0 6.1 6 0 0 6 6 5 3 AAA domain Miro PF08477.8 EAQ89112.1 - 1.8e-10 41.3 2.5 8.6 6.8 0.0 6.9 6 0 0 6 6 6 0 Miro-like protein SRP54 PF00448.17 EAQ89112.1 - 2.5e-10 40.1 1.6 0.43 10.0 0.0 6.8 7 0 0 7 7 7 2 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EAQ89112.1 - 3e-10 39.6 2.0 2.1 7.4 0.0 7.9 8 0 0 8 8 8 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EAQ89112.1 - 1.9e-09 36.9 5.5 0.42 9.6 0.0 6.9 8 0 0 8 8 7 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EAQ89112.1 - 8.5e-09 35.5 12.9 0.81 9.6 0.0 7.3 8 0 0 8 8 6 3 AAA domain NTPase_1 PF03266.10 EAQ89112.1 - 8.4e-08 32.1 5.1 0.8 9.3 0.0 5.9 5 0 0 5 5 5 2 NTPase PduV-EutP PF10662.4 EAQ89112.1 - 8.8e-08 31.7 4.8 0.053 13.0 0.0 6.1 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EAQ89112.1 - 6e-07 29.4 1.3 1.5 8.6 0.0 6.2 7 0 0 7 7 6 1 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 EAQ89112.1 - 9.8e-07 28.7 1.8 27 4.7 0.0 7.0 6 0 0 6 6 6 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EAQ89112.1 - 2.1e-06 26.8 4.8 0.49 9.1 0.1 5.8 6 0 0 6 6 6 1 NB-ARC domain ATP_bind_1 PF03029.12 EAQ89112.1 - 4e-06 26.5 3.1 2.5 7.6 0.0 6.0 6 0 0 6 6 6 1 Conserved hypothetical ATP binding protein cobW PF02492.14 EAQ89112.1 - 4e-06 26.3 5.3 2.5 7.5 0.0 6.1 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EAQ89112.1 - 5e-06 26.0 0.5 0.057 12.8 0.0 4.5 5 0 0 5 5 5 1 CobQ/CobB/MinD/ParA nucleotide binding domain Bac_DnaA PF00308.13 EAQ89112.1 - 6.7e-06 25.8 0.2 5.5 6.5 0.0 5.1 5 0 0 5 5 5 0 Bacterial dnaA protein Viral_helicase1 PF01443.13 EAQ89112.1 - 8.1e-06 25.5 0.1 4.3 6.7 0.0 5.4 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EAQ89112.1 - 1.5e-05 23.9 4.9 0.31 9.6 0.0 5.7 7 0 0 7 7 6 2 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EAQ89112.1 - 4.1e-05 22.4 0.4 2 7.0 0.0 5.1 6 0 0 6 6 6 1 TIP49 C-terminus DAP3 PF10236.4 EAQ89112.1 - 0.00052 19.0 2.1 0.079 11.8 0.0 4.4 5 0 0 5 5 5 1 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.2 EAQ89112.1 - 0.00066 18.8 2.5 9.3 5.2 0.0 4.9 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 APS_kinase PF01583.15 EAQ89112.1 - 0.0021 17.7 0.2 1.2 8.7 0.0 4.5 5 0 0 5 5 4 1 Adenylylsulphate kinase ATP-synt_ab PF00006.20 EAQ89112.1 - 0.004 16.6 0.0 33 3.8 0.0 5.2 5 2 0 6 6 5 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.1 EAQ89112.1 - 0.021 14.8 0.1 5.6 6.8 0.1 3.9 5 0 0 5 5 3 0 AAA domain KaiC PF06745.8 EAQ89112.1 - 0.041 13.0 0.2 41 3.1 0.0 4.6 4 0 0 4 4 4 0 KaiC Phe_ZIP PF08916.6 EAQ89112.1 - 0.047 14.0 0.2 13 6.1 0.0 3.0 2 0 0 2 2 2 0 Phenylalanine zipper PEPCK_ATP PF01293.15 EAQ89112.1 - 0.21 10.0 0.2 0.69 8.3 0.0 1.9 2 0 0 2 2 1 0 Phosphoenolpyruvate carboxykinase Ras PF00071.17 EAQ89112.1 - 0.31 10.4 2.0 1.4e+02 1.8 0.0 4.9 5 0 0 5 5 5 0 Ras family Gtr1_RagA PF04670.7 EAQ89112.1 - 0.86 8.6 4.1 75 2.3 0.0 4.8 6 0 0 6 6 6 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EAQ89112.1 - 0.87 8.5 3.3 39 3.1 0.0 4.1 6 0 0 6 6 4 0 AAA ATPase domain AAA_6 PF12774.2 EAQ89112.1 - 0.91 9.0 0.0 81 2.6 0.0 4.1 6 0 0 6 6 4 0 Hydrolytic ATP binding site of dynein motor region D1 AAA PF00004.24 EAQ89113.1 - 3.3e-50 169.6 0.0 3.3e-42 143.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EAQ89113.1 - 2.8e-07 30.1 0.0 5.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EAQ89113.1 - 1.4e-06 28.4 0.5 9.1e-05 22.5 0.1 3.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EAQ89113.1 - 1.6e-05 24.8 0.0 5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAQ89113.1 - 3.1e-05 24.1 0.0 0.002 18.2 0.0 3.2 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EAQ89113.1 - 5.9e-05 22.8 0.2 0.0075 15.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAQ89113.1 - 9.5e-05 22.0 0.3 0.027 14.2 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EAQ89113.1 - 0.00032 20.6 0.6 0.0093 15.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EAQ89113.1 - 0.0019 18.9 0.8 0.023 15.4 0.0 3.2 4 0 0 4 4 2 1 AAA domain RuvB_N PF05496.7 EAQ89113.1 - 0.0025 16.8 0.0 0.028 13.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EAQ89113.1 - 0.0038 16.8 1.0 0.19 11.3 0.1 3.4 3 1 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EAQ89113.1 - 0.0041 17.2 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 EAQ89113.1 - 0.0048 16.9 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.8 EAQ89113.1 - 0.0058 15.3 0.0 0.013 14.2 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus Bromodomain PF00439.20 EAQ89113.1 - 0.007 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_14 PF13173.1 EAQ89113.1 - 0.0084 16.0 0.0 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.11 EAQ89113.1 - 0.015 14.1 0.0 0.61 8.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Mg_chelatase PF01078.16 EAQ89113.1 - 0.016 14.3 0.2 0.11 11.5 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 EAQ89113.1 - 0.021 13.7 0.0 0.16 10.7 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 EAQ89113.1 - 0.027 13.8 0.0 0.09 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EAQ89113.1 - 0.032 13.8 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EAQ89113.1 - 0.048 13.9 0.0 0.048 13.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Torsin PF06309.6 EAQ89113.1 - 0.082 12.8 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Torsin Sigma54_activat PF00158.21 EAQ89113.1 - 0.082 12.3 0.0 3 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_pol_I_A49 PF06870.7 EAQ89114.1 - 1.4e-63 214.7 0.1 1.8e-53 181.5 0.0 2.1 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor adh_short PF00106.20 EAQ89115.1 - 4.3e-09 36.5 0.0 6.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ89115.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ89115.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain BCNT PF07572.7 EAQ89116.1 - 1.8e-24 85.4 2.0 3.8e-24 84.4 1.4 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development WD40 PF00400.27 EAQ89118.1 - 4.9e-21 73.7 5.8 3.5e-05 23.5 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EAQ89118.1 - 0.0032 17.2 0.0 0.42 10.3 0.0 3.2 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A TFIIF_alpha PF05793.7 EAQ89118.1 - 0.0037 15.7 2.0 0.0052 15.2 1.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SNF2_N PF00176.18 EAQ89119.1 - 1.3e-61 207.9 0.1 1.3e-61 207.9 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain HSA PF07529.8 EAQ89119.1 - 1.8e-15 56.4 10.5 1.8e-15 56.4 7.3 3.8 4 0 0 4 4 4 1 HSA QLQ PF08880.6 EAQ89119.1 - 2.9e-13 48.9 0.3 2.9e-13 48.9 0.2 2.9 3 0 0 3 3 3 1 QLQ Bromodomain PF00439.20 EAQ89120.1 - 1.9e-20 72.5 0.0 4.9e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EAQ89120.1 - 5.5e-17 61.4 0.0 1.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SnAC PF14619.1 EAQ89120.1 - 6.7e-17 61.4 0.3 6.7e-17 61.4 0.2 2.5 2 1 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Zip PF02535.17 EAQ89121.1 - 1e-10 41.1 1.1 1.2e-10 40.9 0.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TauE PF01925.14 EAQ89121.1 - 0.027 13.9 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Endonuclease_NS PF01223.18 EAQ89122.1 - 1.1e-61 208.1 0.0 1.3e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.27 EAQ89123.1 - 1.1e-46 155.0 25.3 2.5e-08 33.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAQ89123.1 - 0.0056 15.4 0.0 0.026 13.2 0.0 2.1 2 1 0 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 EAQ89123.1 - 0.1 12.2 0.0 2.3 7.9 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 EAQ89124.1 - 6.1e-21 74.8 17.9 9.6e-21 74.2 12.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EAQ89124.1 - 0.00011 22.2 4.0 0.00035 20.5 2.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.9 EAQ89125.1 - 5.5e-27 93.8 0.8 1.1e-26 92.8 0.5 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAQ89125.1 - 1.7e-12 47.4 2.5 1.7e-12 47.4 1.8 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.6 EAQ89125.1 - 0.0043 16.4 8.4 0.0052 16.1 5.0 1.8 1 1 1 2 2 2 1 NnrU protein DUF1295 PF06966.7 EAQ89125.1 - 0.026 13.8 1.9 0.037 13.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Cas_csx3 PF09620.5 EAQ89125.1 - 0.13 12.1 0.2 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_csx3) DUF2975 PF11188.3 EAQ89125.1 - 0.41 10.3 6.5 0.45 10.2 3.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2626 PF11117.3 EAQ89126.1 - 0.18 12.2 5.5 0.28 11.6 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) zf-C2H2 PF00096.21 EAQ89129.1 - 9.8e-13 47.6 21.3 0.0007 19.7 0.0 7.0 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ89129.1 - 1.9e-08 34.1 13.1 0.089 13.1 0.0 6.6 6 1 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ89129.1 - 6.1e-08 32.4 22.6 0.0089 16.3 0.1 6.7 7 0 0 7 7 7 3 C2H2-type zinc finger DUF4187 PF13821.1 EAQ89129.1 - 0.00062 19.3 0.2 0.0024 17.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_jaz PF12171.3 EAQ89129.1 - 0.14 12.3 10.1 0.98 9.6 0.2 5.6 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ89129.1 - 0.15 12.3 0.2 0.15 12.3 0.2 4.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type RNA_pol_Rpb6 PF01192.17 EAQ89130.1 - 5.4e-23 80.5 0.2 9.2e-23 79.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 WSC PF01822.14 EAQ89131.1 - 4.8e-33 112.9 27.8 1.4e-18 66.5 7.4 4.7 4 0 0 4 4 4 2 WSC domain PCI PF01399.22 EAQ89132.1 - 6.1e-09 36.1 0.4 5.2e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.17 EAQ89133.1 - 1.1e-26 92.3 0.0 1.4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 EAQ89134.1 - 1.3e-29 102.0 0.0 2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Rdx family Ribosomal_60s PF00428.14 EAQ89134.1 - 0.21 12.0 6.6 4.2 7.8 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Metallophos PF00149.23 EAQ89135.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-HC5HC2H_2 PF13832.1 EAQ89137.1 - 5.6e-34 116.4 8.3 5.6e-34 116.4 5.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAQ89137.1 - 2.8e-26 91.5 7.9 2.8e-26 91.5 5.5 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EAQ89137.1 - 1.2e-18 67.8 0.0 4.4e-18 66.0 0.0 2.0 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EAQ89137.1 - 2.2e-14 52.4 2.1 2.2e-14 52.4 1.4 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EAQ89137.1 - 6.7e-08 32.0 9.7 6.7e-08 32.0 6.7 2.8 2 0 0 2 2 2 1 PHD-finger LRR_4 PF12799.2 EAQ89138.1 - 2.4e-14 52.5 4.7 1.1e-05 24.8 2.0 4.5 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ89138.1 - 4.4e-12 45.5 6.0 1.5e-08 34.2 2.1 3.0 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EAQ89138.1 - 4.8e-07 28.9 10.0 0.49 10.6 0.3 6.2 4 2 2 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EAQ89138.1 - 0.007 16.3 12.9 8.6 7.0 0.0 6.0 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 EAQ89138.1 - 0.11 12.6 5.3 81 3.7 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Biotin_lipoyl PF00364.17 EAQ89142.1 - 1.3e-20 72.8 1.0 2.5e-20 71.8 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EAQ89142.1 - 3.4e-07 29.8 0.0 1.3e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EAQ89142.1 - 0.00015 21.3 0.0 0.0029 17.2 0.0 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 EAQ89142.1 - 0.014 14.5 0.4 2.9 6.9 0.2 2.2 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_3 PF13437.1 EAQ89142.1 - 0.071 13.4 0.2 4.1 7.7 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.11 EAQ89142.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.12 EAQ89143.1 - 2.5e-24 85.5 0.2 5.4e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 CoA-transferase family III UPF0262 PF06793.7 EAQ89143.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Fungal_trans PF04082.13 EAQ89145.1 - 1.2e-26 93.1 0.0 2.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.16 EAQ89146.1 - 4.1e-52 176.0 0.0 6.7e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EAQ89146.1 - 2.9e-12 46.4 0.0 4.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EAQ89146.1 - 0.00098 19.1 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain OPT PF03169.10 EAQ89147.1 - 2.6e-78 264.0 18.4 3e-78 263.8 12.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 EAQ89148.1 - 1.2e-63 215.5 13.2 1.4e-63 215.3 9.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ubiq_cyt_C_chap PF03981.7 EAQ89149.1 - 1.8e-37 128.3 1.4 6.4e-37 126.5 1.0 2.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Ketoacyl-synt_C PF02801.17 EAQ89149.1 - 2.9e-29 101.3 1.3 2.9e-29 101.3 0.9 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EAQ89149.1 - 5.2e-28 98.2 16.2 8.8e-12 45.0 1.7 4.3 3 1 0 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.13 EAQ89149.1 - 0.00094 18.5 0.4 0.0065 15.8 0.3 2.5 1 1 0 1 1 1 1 Thiolase, C-terminal domain Ribosomal_L18p PF00861.17 EAQ89149.1 - 0.054 13.7 0.3 0.18 11.9 0.2 1.9 1 0 0 1 1 1 0 Ribosomal L18p/L5e family DHFR_1 PF00186.14 EAQ89150.1 - 5.7e-10 38.9 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 2 Dihydrofolate reductase Pex14_N PF04695.8 EAQ89150.1 - 0.071 13.1 5.3 0.1 12.6 3.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRCC PF10253.4 EAQ89150.1 - 0.35 11.5 1.7 0.44 11.2 1.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FAM75 PF14650.1 EAQ89150.1 - 4.2 6.6 8.9 5.3 6.3 6.2 1.1 1 0 0 1 1 1 0 FAM75 family TPR_2 PF07719.12 EAQ89151.1 - 8e-09 34.7 20.8 0.014 15.3 0.4 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ89151.1 - 9e-08 32.0 26.8 0.018 15.6 0.2 7.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ89151.1 - 1.4e-07 30.8 5.5 0.38 10.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ89151.1 - 3.1e-07 29.9 5.6 1.2 8.8 0.3 4.8 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EAQ89151.1 - 0.00024 20.6 3.1 0.0046 16.6 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ89151.1 - 0.0021 17.9 9.2 6.4 6.7 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ89151.1 - 0.0026 17.8 4.2 0.11 12.6 0.1 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ89151.1 - 0.0093 15.7 10.8 3.1 7.8 0.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ89151.1 - 0.011 16.0 0.1 0.011 16.0 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ89151.1 - 0.048 14.1 9.2 2.1 8.9 0.4 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ89151.1 - 0.065 13.9 37.2 0.031 14.9 1.3 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat FadA PF09403.5 EAQ89151.1 - 0.07 13.1 0.3 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 Adhesion protein FadA RIX1 PF08167.7 EAQ89152.1 - 3e-43 147.3 3.6 2.9e-42 144.1 0.1 2.3 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis SBP_bac_11 PF13531.1 EAQ89152.1 - 0.067 12.8 0.5 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF4587 PF15248.1 EAQ89152.1 - 0.16 12.5 2.6 0.42 11.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) Glyco_hydro_16 PF00722.16 EAQ89155.1 - 7e-08 31.9 0.2 1.1e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2510 PF10708.4 EAQ89155.1 - 0.95 8.9 6.8 6.7 6.2 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2510) Fungal_lectin PF07938.7 EAQ89156.1 - 1.7e-09 37.4 0.9 0.00015 21.2 0.2 2.3 1 1 1 2 2 2 2 Fungal fucose-specific lectin Dus PF01207.12 EAQ89157.1 - 5.7e-38 130.4 0.0 9.8e-32 110.0 0.0 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EAQ89157.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF1190 PF06693.6 EAQ89159.1 - 0.17 11.9 0.6 0.18 11.8 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) MIF4G PF02854.14 EAQ89160.1 - 5.2e-26 91.3 1.7 5.2e-26 91.3 1.2 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EAQ89160.1 - 1.4e-23 82.7 0.0 3.7e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 MA3 domain FAM176 PF14851.1 EAQ89160.1 - 0.45 10.1 4.4 0.93 9.1 3.1 1.5 1 0 0 1 1 1 0 FAM176 family DPM2 PF07297.7 EAQ89161.1 - 2e-36 124.1 1.9 2.6e-36 123.7 1.3 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EAQ89161.1 - 3.4e-05 23.4 1.0 4.8e-05 22.9 0.7 1.2 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EAQ89161.1 - 0.0094 15.8 1.8 0.0094 15.8 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 EAQ89161.1 - 0.047 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) COX14 PF14880.1 EAQ89161.1 - 0.28 10.8 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly SnoaL_4 PF13577.1 EAQ89163.1 - 0.09 12.6 0.1 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain ING PF12998.2 EAQ89164.1 - 0.013 15.7 0.2 0.042 14.1 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Bactofilin PF04519.8 EAQ89165.1 - 2.6e-06 27.3 0.2 3.3e-05 23.8 0.1 2.2 1 1 1 2 2 2 2 Polymer-forming cytoskeletal DUF342 PF03961.8 EAQ89165.1 - 0.0017 16.8 0.6 0.0029 16.0 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF342) DUF4428 PF14471.1 EAQ89165.1 - 0.51 10.1 2.1 3.5 7.4 1.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) zf-C2H2 PF00096.21 EAQ89167.1 - 0.019 15.2 3.4 0.05 13.9 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ89167.1 - 0.035 14.4 2.9 0.091 13.1 2.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ89167.1 - 0.12 12.7 1.5 19 5.8 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF3602 PF12223.3 EAQ89168.1 - 1.3e-10 41.5 14.3 0.0019 18.5 2.2 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DnaJ PF00226.26 EAQ89169.1 - 2.1e-07 30.5 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EAQ89169.1 - 5.7e-06 26.1 0.1 7e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Pam16 TMP_2 PF06791.8 EAQ89169.1 - 0.0086 15.7 0.1 0.0086 15.7 0.0 1.1 1 0 0 1 1 1 1 Prophage tail length tape measure protein DUF4538 PF15061.1 EAQ89169.1 - 0.036 13.3 0.0 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) ScpA_ScpB PF02616.9 EAQ89170.1 - 0.032 13.8 0.3 4 6.9 0.0 2.2 2 0 0 2 2 2 0 ScpA/B protein Ku PF02735.11 EAQ89171.1 - 4.2e-27 94.8 0.0 8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EAQ89171.1 - 5.7e-22 78.2 0.0 9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EAQ89171.1 - 9e-16 57.8 0.0 2.3e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 EAQ89171.1 - 2e-05 24.7 0.1 7.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EAQ89171.1 - 0.0022 17.7 0.1 0.0062 16.2 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF605 PF04652.11 EAQ89172.1 - 1.4 8.2 19.8 1.8 7.8 13.7 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EAQ89172.1 - 4.2 5.5 9.7 4.4 5.4 6.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1295 PF06966.7 EAQ89173.1 - 6e-35 120.6 8.7 1.9e-34 119.0 6.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.15 EAQ89174.1 - 6.1e-74 249.2 0.0 1.2e-49 169.2 0.0 3.1 2 1 1 3 3 3 3 DNA topoisomerase Toprim PF01751.17 EAQ89174.1 - 9.6e-05 22.3 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.4 EAQ89175.1 - 5.5e-38 128.5 0.0 8.6e-38 127.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein SET PF00856.23 EAQ89178.1 - 4.8e-06 26.9 0.1 0.00041 20.6 0.1 2.9 1 1 1 2 2 2 1 SET domain TPR_11 PF13414.1 EAQ89178.1 - 0.026 14.1 1.0 2 8.1 0.6 2.6 2 0 0 2 2 2 0 TPR repeat DUF164 PF02591.10 EAQ89178.1 - 0.37 10.6 5.7 1.2 8.9 0.3 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 EAQ89178.1 - 1.2 9.0 5.9 0.36 10.8 1.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-MYND PF01753.13 EAQ89178.1 - 1.4 8.8 12.7 0.093 12.6 4.1 2.6 2 0 0 2 2 2 0 MYND finger DZR PF12773.2 EAQ89178.1 - 1.5 8.6 12.4 0.098 12.4 3.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon Hydrolase_6 PF13344.1 EAQ89179.1 - 1.3e-23 82.7 0.0 2.3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ89179.1 - 3.6e-12 47.1 0.0 2.1e-05 25.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ89179.1 - 5e-10 38.9 0.1 1.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EAQ89179.1 - 6.5e-07 29.7 0.0 0.00033 20.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Glucosamine_iso PF01182.15 EAQ89180.1 - 3e-60 203.3 0.0 3.5e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_76 PF03663.9 EAQ89181.1 - 1.7e-53 182.3 12.5 2.3e-53 181.9 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF1680 PF07944.7 EAQ89181.1 - 2.3e-06 26.1 1.5 0.014 13.6 0.2 2.7 2 1 1 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_88 PF07470.8 EAQ89181.1 - 0.0017 17.4 4.6 0.096 11.7 0.0 3.1 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EAQ89181.1 - 0.014 14.6 1.4 4.3 6.5 0.0 2.8 3 1 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus zf-C2H2 PF00096.21 EAQ89185.1 - 7.9e-08 32.2 17.9 1.4e-05 25.1 2.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ89185.1 - 2.5e-05 24.3 3.8 2.5e-05 24.3 2.7 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EAQ89185.1 - 0.00032 20.7 1.8 0.00083 19.4 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EAQ89185.1 - 0.0005 20.2 0.9 0.0005 20.2 0.6 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger ARS2 PF04959.8 EAQ89185.1 - 0.0055 16.9 2.3 0.0055 16.9 1.6 2.8 2 1 0 2 2 2 1 Arsenite-resistance protein 2 zf-met PF12874.2 EAQ89185.1 - 0.052 13.7 0.8 0.3 11.3 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAQ89185.1 - 0.15 11.9 2.2 0.55 10.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.13 EAQ89185.1 - 1.5 9.2 8.2 0.19 12.1 2.4 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 EAQ89185.1 - 9.2 6.4 9.8 4.9 7.3 3.5 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Serglycin PF04360.7 EAQ89186.1 - 0.084 12.6 0.3 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Serglycin zf-rbx1 PF12678.2 EAQ89186.1 - 0.13 12.4 4.9 0.51 10.4 3.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EAQ89186.1 - 0.14 12.0 10.9 0.068 13.0 2.7 3.3 3 0 0 3 3 3 0 Ring finger domain DUF2361 PF10153.4 EAQ89187.1 - 1.2e-37 128.5 6.7 1.2e-37 128.5 4.6 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) FAM110_N PF14161.1 EAQ89187.1 - 1.7 8.9 7.9 0.89 9.8 3.4 2.0 2 0 0 2 2 2 0 Centrosome-associated N terminus PTS_2-RNA PF01885.11 EAQ89190.1 - 6.7e-65 217.8 0.0 8.1e-65 217.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DSPc PF00782.15 EAQ89194.1 - 2.1e-23 82.3 0.0 1.4e-21 76.4 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAQ89194.1 - 0.0016 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TFIIIC_sub6 PF10419.4 EAQ89194.1 - 0.048 13.1 0.2 0.6 9.6 0.0 2.5 3 0 0 3 3 3 0 TFIIIC subunit UAA PF08449.6 EAQ89195.1 - 7e-72 241.8 6.3 2.6e-71 240.0 4.4 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EAQ89195.1 - 9e-12 45.1 21.4 2.8e-06 27.4 2.3 3.4 3 0 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 EAQ89195.1 - 5.3e-06 25.7 2.0 0.023 13.8 0.3 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EAQ89195.1 - 1e-05 25.6 19.4 0.00037 20.6 4.5 3.1 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EAQ89195.1 - 7.3e-05 22.4 5.1 7.3e-05 22.4 3.5 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family L6_membrane PF05805.7 EAQ89195.1 - 3.2 7.2 7.6 0.72 9.3 1.0 2.4 1 1 1 2 2 2 0 L6 membrane protein KH_1 PF00013.24 EAQ89196.1 - 2.4e-39 132.7 13.0 9.7e-16 57.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EAQ89196.1 - 2e-30 103.8 14.0 6.5e-12 44.8 1.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EAQ89196.1 - 4.2e-10 39.0 10.7 0.0098 15.4 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EAQ89196.1 - 2e-08 33.7 4.8 0.035 13.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EAQ89196.1 - 0.0002 21.1 5.0 0.31 10.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EAQ89196.1 - 0.0025 17.2 0.4 0.49 9.8 0.0 3.1 3 0 0 3 3 3 1 dUTPase F-box-like PF12937.2 EAQ89198.1 - 4.4e-08 32.7 0.1 7e-07 28.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EAQ89198.1 - 7.3e-07 28.6 8.7 0.82 9.9 0.0 7.4 10 0 0 10 10 10 2 Leucine Rich repeat F-box PF00646.28 EAQ89198.1 - 8.4e-06 25.3 0.2 2.6e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 EAQ89198.1 - 9e-05 21.9 11.8 1.1 9.5 0.1 6.9 8 0 0 8 8 8 2 Leucine Rich Repeat Pkinase PF00069.20 EAQ89199.1 - 1.3e-57 194.8 0.0 1.9e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89199.1 - 5.4e-20 71.5 0.0 8.3e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89199.1 - 2.3e-08 33.3 0.0 4.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ89199.1 - 2.9e-05 23.9 0.4 0.00068 19.4 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EAQ89199.1 - 4.2e-05 22.6 0.0 9.3e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAQ89199.1 - 0.0023 17.3 0.1 0.0042 16.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EAQ89199.1 - 0.017 15.4 0.0 0.54 10.6 0.0 2.9 2 1 0 2 2 2 0 PAS domain STE3 PF02076.10 EAQ89200.1 - 7.1e-32 110.6 19.6 4.2e-31 108.0 12.0 2.2 1 1 1 2 2 2 1 Pheromone A receptor DUF1980 PF09323.5 EAQ89200.1 - 0.016 14.9 0.6 6.9 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3671 PF12420.3 EAQ89200.1 - 6.4 6.8 7.4 0.76 9.7 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function GIDA PF01134.17 EAQ89201.1 - 1.8e-155 517.6 0.0 2.2e-155 517.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EAQ89201.1 - 1.1e-17 63.8 0.0 2.6e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 SSB PF00436.20 EAQ89201.1 - 2.3e-16 59.5 0.0 4.1e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Pyr_redox_2 PF07992.9 EAQ89201.1 - 3.2e-06 27.1 1.1 8.7e-06 25.7 0.8 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ89201.1 - 8.6e-06 25.0 0.6 1.6e-05 24.2 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ89201.1 - 0.00021 20.2 1.6 0.00056 18.8 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ89201.1 - 0.00061 18.7 2.5 0.39 9.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EAQ89201.1 - 0.0076 15.8 0.2 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EAQ89201.1 - 0.025 13.0 1.2 0.12 10.8 0.6 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EAQ89201.1 - 0.14 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CDP-OH_P_transf PF01066.16 EAQ89202.1 - 2e-15 56.9 6.0 2e-15 56.9 4.2 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.4 EAQ89203.1 - 4.2e-07 29.9 0.0 1.6e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family Tyr-DNA_phospho PF06087.7 EAQ89204.1 - 3.2e-68 230.4 0.0 3.9e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EAQ89204.1 - 2.8e-05 23.8 0.0 0.0079 15.9 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EAQ89204.1 - 0.37 10.4 0.0 0.37 10.4 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin interaction motif PNRC PF15365.1 EAQ89205.1 - 1.8e-05 24.6 3.8 1.8e-05 24.6 2.6 5.0 5 1 0 5 5 5 3 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EAQ89207.1 - 2.4e-17 62.7 2.6 3.1e-17 62.4 1.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAQ89207.1 - 5e-06 26.2 1.5 6.2e-06 25.9 1.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPC12 PF06645.8 EAQ89208.1 - 1.3e-28 98.6 0.2 1.6e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 EAQ89208.1 - 0.0067 16.7 0.1 0.008 16.5 0.1 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein ZYG-11_interact PF05884.7 EAQ89208.1 - 0.0073 15.4 0.1 0.0082 15.2 0.0 1.0 1 0 0 1 1 1 1 Interactor of ZYG-11 NUDIX-like PF09296.6 EAQ89208.1 - 0.044 14.1 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain Sec62 PF03839.11 EAQ89208.1 - 0.13 11.6 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CorA PF01544.13 EAQ89209.1 - 2.8e-42 144.7 0.0 4.2e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 EAQ89210.1 - 8.3e-22 76.2 1.4 1e-21 75.9 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.8 EAQ89211.1 - 4.4e-19 68.2 12.9 4.4e-19 68.2 9.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EAQ89211.1 - 3.9e-16 58.7 1.2 9.4e-16 57.5 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 P2 PF07194.6 EAQ89211.1 - 0.13 12.1 0.2 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain DUF3321 PF11968.3 EAQ89212.1 - 1.2e-79 266.9 0.0 1.7e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EAQ89212.1 - 4.8e-05 23.1 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF1929 PF09118.6 EAQ89212.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) Methyltransf_12 PF08242.7 EAQ89212.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain HAD_2 PF13419.1 EAQ89213.1 - 5.1e-30 104.9 0.0 6.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ89213.1 - 0.00072 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Pkinase PF00069.20 EAQ89214.1 - 1e-35 123.1 0.0 1.9e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89214.1 - 2.7e-18 66.0 0.0 4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89214.1 - 9.5e-06 24.7 0.0 0.0027 16.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EAQ89214.1 - 0.0039 16.2 0.0 0.0079 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.13 EAQ89215.1 - 6.9e-18 64.3 0.5 2.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF1517 PF07466.6 EAQ89215.1 - 0.021 13.8 2.5 0.029 13.3 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) KfrA_N PF11740.3 EAQ89216.1 - 0.12 12.8 0.4 32 5.0 0.0 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DEAD PF00270.24 EAQ89217.1 - 2.2e-19 69.5 0.0 4.6e-18 65.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ89217.1 - 3.5e-17 62.0 0.1 6.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ89217.1 - 9.2e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CorA PF01544.13 EAQ89218.1 - 5.5e-05 22.3 1.2 5.5e-05 22.3 0.8 2.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Phi-29_GP16_7 PF06720.6 EAQ89218.1 - 0.004 16.8 0.5 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Bacteriophage phi-29 early protein GP16.7 DUF4381 PF14316.1 EAQ89218.1 - 0.2 11.7 4.5 0.96 9.5 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Pkinase PF00069.20 EAQ89219.1 - 2.1e-12 46.7 0.0 3.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89219.1 - 0.00042 19.4 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89219.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3306 PF11748.3 EAQ89219.1 - 1.5 9.4 11.8 3.5 8.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Amelogenin PF02948.10 EAQ89219.1 - 3.6 8.1 24.3 0.78 10.3 8.7 2.5 2 0 0 2 2 2 0 Amelogenin Lectin_leg-like PF03388.8 EAQ89220.1 - 2.5e-31 108.6 0.2 3.4e-20 72.1 0.2 2.1 2 0 0 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.14 EAQ89220.1 - 0.0038 16.6 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.10 EAQ89221.1 - 2e-21 75.0 0.6 2.4e-21 74.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PMEI PF04043.10 EAQ89221.1 - 0.058 13.3 0.1 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor PI-PLC-X PF00388.14 EAQ89222.1 - 1.1e-60 203.2 0.0 2.2e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF2040 PF09745.4 EAQ89222.1 - 4.8e-41 139.5 14.0 4.8e-41 139.5 9.7 3.3 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) PI-PLC-Y PF00387.14 EAQ89222.1 - 1.9e-39 134.2 0.0 4.4e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Actin PF00022.14 EAQ89223.1 - 1e-25 90.0 0.0 5.3e-16 58.0 0.0 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EAQ89223.1 - 0.032 12.8 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein DUF4451 PF14616.1 EAQ89225.1 - 3.5e-34 117.2 0.1 6.4e-34 116.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) S-AdoMet_synt_C PF02773.11 EAQ89226.1 - 1.1e-76 255.2 0.3 1.9e-76 254.3 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EAQ89226.1 - 1.8e-46 156.9 0.0 3e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EAQ89226.1 - 8.3e-41 138.2 0.2 2.1e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain YfcL PF08891.6 EAQ89227.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 YfcL protein THF_DHG_CYH PF00763.18 EAQ89228.1 - 1.9e-20 73.0 0.0 2.7e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EAQ89228.1 - 6.9e-14 51.2 0.1 7.4e-09 34.8 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 EAQ89228.1 - 0.0076 15.1 0.4 0.011 14.6 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle FAM150 PF15129.1 EAQ89228.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 FAM150 family MMS19_N PF14500.1 EAQ89229.1 - 5.2e-30 104.5 0.3 2.9e-28 98.8 0.1 2.9 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II SPC25 PF06703.6 EAQ89230.1 - 5.7e-52 175.5 0.0 6.9e-52 175.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2271 PF10029.4 EAQ89230.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) DUF106 PF01956.11 EAQ89231.1 - 1.9e-29 102.3 3.6 3.5e-19 68.9 0.6 2.3 2 0 0 2 2 2 2 Integral membrane protein DUF106 DUF4574 PF15141.1 EAQ89234.1 - 0.051 13.3 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) DHQ_synthase PF01761.15 EAQ89234.1 - 0.091 11.6 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase SET PF00856.23 EAQ89235.1 - 4e-11 43.4 0.0 5.9e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.16 EAQ89236.1 - 1.7e-33 114.0 0.2 2.6e-33 113.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_hydro_53 PF07745.8 EAQ89237.1 - 1.9e-120 401.6 4.0 2.2e-120 401.4 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 ADH_zinc_N PF00107.21 EAQ89238.1 - 1.2e-05 24.8 0.0 2.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ89238.1 - 0.032 13.9 0.0 0.091 12.5 0.0 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glutaredoxin PF00462.19 EAQ89239.1 - 6.9e-13 48.3 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Ribosomal_L21p PF00829.16 EAQ89241.1 - 0.0093 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 EAQ89242.1 - 1.5e-16 60.3 0.0 3.9e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89242.1 - 1.4e-05 24.3 0.0 0.00012 21.2 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Ribosomal_60s PF00428.14 EAQ89243.1 - 8.9e-29 99.7 12.0 1e-28 99.5 8.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.6 EAQ89244.1 - 1.2e-06 28.7 26.5 1.2e-06 28.7 18.4 2.8 3 1 0 3 3 3 1 SPT2 chromatin protein Ribosomal_S8e PF01201.17 EAQ89245.1 - 2.7e-17 63.1 19.5 8.4e-16 58.3 13.5 2.3 1 1 0 1 1 1 1 Ribosomal protein S8e IBR PF01485.16 EAQ89246.1 - 7.5e-07 28.9 0.9 7.5e-07 28.9 0.6 2.6 2 1 0 2 2 2 1 IBR domain zf-RING_5 PF14634.1 EAQ89246.1 - 0.027 14.2 8.7 0.027 14.2 6.0 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 EAQ89246.1 - 4 7.3 18.0 0.054 13.3 6.2 2.4 2 0 0 2 2 2 0 Ring finger domain HET PF06985.6 EAQ89247.1 - 5.2e-20 72.0 0.0 9.9e-20 71.1 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIF1 PF05970.9 EAQ89249.1 - 8.2e-18 64.4 0.0 2.8e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase Ank_2 PF12796.2 EAQ89249.1 - 4.5e-14 52.5 0.0 1e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ89249.1 - 2e-11 43.0 0.9 0.00021 20.9 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat NACHT PF05729.7 EAQ89249.1 - 2.3e-10 40.3 0.1 4.8e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ89249.1 - 1e-06 28.9 0.7 1e-06 28.9 0.5 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EAQ89249.1 - 5e-06 26.2 1.5 0.002 17.7 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 EAQ89249.1 - 0.00011 22.4 0.0 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 EAQ89249.1 - 0.00011 22.5 0.0 0.0023 18.4 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ89249.1 - 0.00013 22.1 0.0 0.0045 17.1 0.1 2.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) NB-ARC PF00931.17 EAQ89249.1 - 0.00071 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EAQ89249.1 - 0.0026 17.6 0.0 0.23 11.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ89249.1 - 0.018 14.7 0.0 0.099 12.3 0.0 2.1 3 0 0 3 3 3 0 Archaeal ATPase Ank_3 PF13606.1 EAQ89249.1 - 0.035 14.3 0.0 6.4 7.3 0.0 3.2 3 0 0 3 3 2 0 Ankyrin repeat HA PF03457.9 EAQ89249.1 - 0.096 12.8 2.3 0.16 12.0 0.1 2.5 3 0 0 3 3 3 0 Helicase associated domain Fungal_trans PF04082.13 EAQ89253.1 - 6.8e-10 38.2 0.5 1.1e-09 37.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EAQ89254.1 - 2.1e-19 69.7 0.0 3.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ89254.1 - 1.8e-11 43.6 0.4 1.3e-05 24.2 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ89254.1 - 1.9e-05 24.9 0.1 0.00048 20.4 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ89254.1 - 0.00038 20.4 0.1 0.00094 19.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ89254.1 - 0.0031 16.4 0.1 0.0047 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EAQ89254.1 - 0.005 16.2 0.1 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EAQ89254.1 - 0.0096 15.8 0.1 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EAQ89254.1 - 0.031 12.9 0.0 0.36 9.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase N2227 PF07942.7 EAQ89255.1 - 2.1e-09 36.7 0.0 3.5e-06 26.1 0.0 2.8 2 1 1 3 3 3 2 N2227-like protein Cluap1 PF10234.4 EAQ89255.1 - 0.0013 17.9 0.8 0.0029 16.8 0.1 1.8 1 1 0 1 1 1 1 Clusterin-associated protein-1 PMI_typeI PF01238.16 EAQ89255.1 - 0.057 12.3 0.2 5.3 5.9 0.1 2.1 1 1 0 2 2 2 0 Phosphomannose isomerase type I DUF1153 PF06627.6 EAQ89255.1 - 0.11 12.3 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) FlgN PF05130.7 EAQ89255.1 - 0.35 11.1 4.7 0.6 10.3 2.9 1.6 1 1 1 2 2 2 0 FlgN protein Pyr_redox_3 PF13738.1 EAQ89261.1 - 2.1e-13 50.7 0.0 4.1e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ89261.1 - 0.00021 20.3 0.0 0.32 9.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAQ89261.1 - 0.075 12.9 1.3 13 5.6 0.8 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ89261.1 - 4.3 7.0 5.0 2 8.1 0.3 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding WSC PF01822.14 EAQ89262.1 - 1e-62 208.0 47.1 6.6e-19 67.6 4.0 4.1 4 0 0 4 4 4 4 WSC domain GCR1_C PF12550.3 EAQ89264.1 - 5.6e-18 64.5 0.1 2.8e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Pkinase PF00069.20 EAQ89264.1 - 2.7e-08 33.2 0.0 0.00051 19.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89264.1 - 0.068 12.2 0.0 4.6 6.2 0.0 2.4 1 1 1 2 2 2 0 Protein tyrosine kinase HalX PF08663.5 EAQ89264.1 - 0.12 12.3 2.0 0.41 10.6 1.4 1.9 1 0 0 1 1 1 0 HalX domain zf-C2H2 PF00096.21 EAQ89266.1 - 0.014 15.7 0.4 0.014 15.7 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type SelP_N PF04592.9 EAQ89266.1 - 0.11 11.9 15.8 0.22 10.8 11.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EAQ89266.1 - 4.6 6.1 16.1 7.1 5.5 11.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AHH PF14412.1 EAQ89268.1 - 0.19 11.7 5.5 0.27 11.2 3.8 1.4 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Glycoprotein_B PF00606.13 EAQ89271.1 - 0.0036 15.4 0.0 0.0064 14.5 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Moricin PF06451.6 EAQ89271.1 - 0.14 11.6 0.2 0.14 11.6 0.1 2.5 2 0 0 2 2 2 0 Moricin DUF1376 PF07120.6 EAQ89271.1 - 0.19 11.8 0.7 14 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1376) HLH PF00010.21 EAQ89272.1 - 1.3e-11 43.9 1.1 1.3e-11 43.9 0.7 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3106 PF11304.3 EAQ89272.1 - 0.015 15.6 2.5 2.2 8.7 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) RRM_1 PF00076.17 EAQ89274.1 - 1.3e-35 120.8 0.0 1.8e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89274.1 - 4.3e-27 93.9 0.0 1.4e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89274.1 - 5.7e-14 51.7 0.0 1e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EAQ89274.1 - 0.06 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain TPR_11 PF13414.1 EAQ89275.1 - 1e-23 82.7 12.1 2.3e-09 36.7 0.4 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EAQ89275.1 - 3.6e-23 80.1 10.9 8.8e-08 31.4 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ89275.1 - 1e-21 75.0 15.8 8.3e-07 28.4 0.1 6.3 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ89275.1 - 1.4e-18 65.7 11.9 5.6e-06 26.5 0.1 6.3 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ89275.1 - 8.4e-18 63.0 7.6 0.001 19.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ89275.1 - 2.1e-15 56.9 18.9 1.8e-06 28.4 0.1 5.0 4 2 1 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ89275.1 - 1.8e-14 52.3 1.1 0.00043 19.8 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ89275.1 - 2.9e-14 51.6 6.0 0.0013 18.3 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ89275.1 - 9.4e-14 51.1 8.1 5.2e-08 32.7 0.3 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ89275.1 - 5.3e-12 45.9 11.6 0.00027 21.2 3.4 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.1 EAQ89275.1 - 5.2e-10 39.3 3.8 0.031 14.3 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ89275.1 - 1.9e-09 37.2 3.4 0.0019 17.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ89275.1 - 5.4e-09 35.9 5.3 0.17 12.4 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EAQ89275.1 - 8.9e-05 21.6 1.3 0.16 11.0 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EAQ89275.1 - 0.0074 16.0 1.4 5.1 7.0 0.3 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1641 PF07849.6 EAQ89275.1 - 0.14 11.7 0.2 0.37 10.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TPR_10 PF13374.1 EAQ89275.1 - 0.21 11.5 13.9 0.25 11.3 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EAQ89275.1 - 0.33 10.5 2.0 13 5.3 0.0 3.9 4 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 RNase_T PF00929.19 EAQ89276.1 - 5.8e-23 81.9 0.0 1.2e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EAQ89276.1 - 0.19 11.2 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease Yippee-Mis18 PF03226.9 EAQ89277.1 - 2.2e-05 24.3 0.3 5.5e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Baculo_PEP_C PF04513.7 EAQ89277.1 - 0.0011 18.8 0.3 1.1 9.0 0.0 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus PspA_IM30 PF04012.7 EAQ89277.1 - 0.0011 18.3 1.1 0.52 9.6 0.1 2.3 1 1 0 2 2 2 2 PspA/IM30 family Reo_sigmaC PF04582.7 EAQ89277.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein ATG16 PF08614.6 EAQ89277.1 - 0.0015 18.3 0.5 0.41 10.4 0.1 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 EAQ89277.1 - 0.0016 18.2 0.4 0.31 10.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) IncA PF04156.9 EAQ89277.1 - 0.0024 17.5 0.4 0.025 14.1 0.2 2.3 1 1 1 2 2 2 1 IncA protein Prefoldin_2 PF01920.15 EAQ89277.1 - 0.0063 16.2 1.9 1.4 8.7 0.0 3.2 1 1 2 3 3 3 1 Prefoldin subunit TMF_TATA_bd PF12325.3 EAQ89277.1 - 0.0065 16.1 0.8 0.48 10.1 0.0 2.5 1 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 EAQ89277.1 - 0.0075 16.4 1.8 0.059 13.4 0.0 2.7 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family GAS PF13851.1 EAQ89277.1 - 0.008 15.3 0.6 0.7 9.0 0.0 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DapB_N PF01113.15 EAQ89277.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WEMBL PF05701.6 EAQ89277.1 - 0.013 14.0 0.1 0.021 13.2 0.0 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SlyX PF04102.7 EAQ89277.1 - 0.015 15.6 1.1 0.82 10.0 0.0 2.9 2 1 0 2 2 2 0 SlyX Myosin_tail_1 PF01576.14 EAQ89277.1 - 0.024 12.4 1.7 1 6.9 0.0 2.0 1 1 0 2 2 2 0 Myosin tail DUF972 PF06156.8 EAQ89277.1 - 0.024 14.9 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Sec3_C PF09763.4 EAQ89277.1 - 0.026 12.6 0.1 0.29 9.2 0.0 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec3 NPV_P10 PF05531.7 EAQ89277.1 - 0.028 14.6 0.3 3 8.1 0.1 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 EAQ89277.1 - 0.037 13.9 1.4 0.32 10.8 0.1 2.6 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EAQ89277.1 - 0.043 12.4 0.3 0.75 8.3 0.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_GPO PF05929.6 EAQ89277.1 - 0.056 12.6 0.5 0.12 11.6 0.2 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Filament PF00038.16 EAQ89277.1 - 0.057 12.8 1.6 3.2 7.1 0.1 2.2 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 EAQ89277.1 - 0.059 13.2 0.6 14 5.6 0.0 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 EAQ89277.1 - 0.08 12.6 1.7 17 5.2 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) COMP PF11598.3 EAQ89277.1 - 0.094 12.8 0.8 2.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein CENP-F_leu_zip PF10473.4 EAQ89277.1 - 0.12 12.2 2.4 30 4.4 0.0 3.1 1 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 EAQ89277.1 - 0.14 10.3 0.1 0.43 8.7 0.1 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) WXG100 PF06013.7 EAQ89277.1 - 0.17 11.8 1.3 23 5.0 0.1 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG K-box PF01486.12 EAQ89277.1 - 0.18 11.5 1.8 0.62 9.8 0.0 2.6 3 0 0 3 3 3 0 K-box region TMF_DNA_bd PF12329.3 EAQ89277.1 - 0.19 11.5 2.3 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1515 PF07439.6 EAQ89277.1 - 0.19 11.5 1.1 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Atg14 PF10186.4 EAQ89277.1 - 0.23 10.3 2.0 2 7.3 0.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EAQ89280.1 - 2.3e-25 88.5 0.1 3.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EAQ89280.1 - 0.014 15.0 0.2 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Cep57_MT_bd PF06657.8 EAQ89280.1 - 0.026 14.4 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 G3P_antiterm PF04309.7 EAQ89281.1 - 0.085 11.8 0.1 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Strep_SA_rep PF06696.6 EAQ89281.1 - 0.14 11.9 0.9 0.31 10.8 0.6 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat AAA PF00004.24 EAQ89282.1 - 2.3e-14 53.7 0.0 4.2e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ89282.1 - 6.2e-11 42.6 0.3 7.2e-10 39.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ89282.1 - 1e-07 32.1 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 EAQ89282.1 - 1.6e-05 24.6 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 BAH domain AAA_17 PF13207.1 EAQ89282.1 - 0.00019 22.2 0.0 0.00094 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ89282.1 - 0.00055 19.6 0.3 0.0026 17.4 0.2 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EAQ89282.1 - 0.0077 16.5 0.1 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAQ89282.1 - 0.01 15.8 0.0 0.089 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 EAQ89282.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 EAQ89282.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAQ89282.1 - 0.04 13.7 0.6 0.56 10.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.4 EAQ89282.1 - 0.042 12.8 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EAQ89282.1 - 0.042 13.2 0.0 2.7 7.3 0.0 2.4 2 1 1 3 3 3 0 AAA-like domain AAA_32 PF13654.1 EAQ89282.1 - 0.051 12.2 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ89282.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EAQ89282.1 - 0.11 12.1 0.0 1.1 8.9 0.0 2.4 1 1 0 1 1 1 0 Archaeal ATPase Pol_alpha_B_N PF08418.5 EAQ89282.1 - 2.9 7.3 5.6 0.76 9.2 1.4 1.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal WD40 PF00400.27 EAQ89283.1 - 1e-53 177.3 13.6 5.3e-10 38.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAQ89283.1 - 0.01 13.9 2.8 8.6 4.3 0.6 4.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TMF_TATA_bd PF12325.3 EAQ89284.1 - 7.1e-20 70.9 1.2 7.1e-20 70.9 0.8 6.9 3 3 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EAQ89284.1 - 1.8e-17 62.8 13.7 1.8e-17 62.8 9.5 8.8 4 2 4 8 8 8 3 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EAQ89284.1 - 0.0011 18.8 16.4 0.0011 18.8 11.4 5.1 3 1 2 5 5 5 2 Tropomyosin like Reo_sigmaC PF04582.7 EAQ89284.1 - 0.025 13.7 17.1 0.54 9.3 1.0 3.8 2 1 1 4 4 4 0 Reovirus sigma C capsid protein BRE1 PF08647.6 EAQ89284.1 - 0.29 11.1 0.0 0.29 11.1 0.0 6.3 3 1 2 6 6 6 0 BRE1 E3 ubiquitin ligase MtrG PF04210.8 EAQ89284.1 - 1.8 8.3 7.3 4.4 7.0 0.1 4.1 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G FlaC_arch PF05377.6 EAQ89284.1 - 2.9 7.8 14.6 23 4.9 0.3 5.4 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Ceramidase PF05875.7 EAQ89286.1 - 2.7e-87 292.2 10.3 3.7e-87 291.8 7.2 1.1 1 0 0 1 1 1 1 Ceramidase Prefoldin_2 PF01920.15 EAQ89286.1 - 1.1e-19 70.1 0.2 1.7e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 EAQ89286.1 - 0.017 14.8 1.5 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.1 EAQ89286.1 - 0.35 10.8 7.3 2 8.4 2.4 2.2 2 0 0 2 2 2 0 FlxA-like protein Mito_carr PF00153.22 EAQ89288.1 - 1.7e-50 168.6 2.8 1.4e-18 66.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2638 PF10937.3 EAQ89288.1 - 0.23 12.5 1.3 0.74 10.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) DUF3439 PF11921.3 EAQ89288.1 - 1.1 8.9 6.6 1.6 8.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1908 PF08926.6 EAQ89288.1 - 6.2 5.4 6.2 9.4 4.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Dor1 PF04124.7 EAQ89289.1 - 7.5e-61 205.4 7.4 1.3e-57 194.8 3.4 3.6 2 2 1 3 3 3 3 Dor1-like family Latarcin PF10279.4 EAQ89289.1 - 0.11 12.7 0.0 0.82 9.9 0.0 2.2 2 1 0 2 2 2 0 Latarcin precursor COG5 PF10392.4 EAQ89289.1 - 1.3 8.9 8.0 0.57 10.1 2.6 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 TRAM_LAG1_CLN8 PF03798.11 EAQ89292.1 - 5.8e-50 169.5 9.2 9.1e-50 168.9 6.4 1.3 1 0 0 1 1 1 1 TLC domain SHD1 PF03983.7 EAQ89293.1 - 3e-36 122.8 0.0 5.3e-36 122.1 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EAQ89293.1 - 1.1e-28 98.3 5.1 8.7e-11 41.0 0.1 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.1 EAQ89293.1 - 1.9e-27 94.6 5.2 2.9e-09 36.3 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EAQ89293.1 - 5.2e-21 73.8 0.3 3.4e-06 26.4 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EAQ89293.1 - 3e-07 30.5 2.8 0.32 11.2 0.3 3.4 3 0 0 3 3 3 3 Bacterial SH3 domain A_deaminase PF00962.17 EAQ89294.1 - 5.5e-108 360.8 0.1 7.4e-108 360.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 EAQ89295.1 - 6.3e-97 324.1 6.3 8e-97 323.8 4.4 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EAQ89295.1 - 5.4e-05 22.4 0.4 5.4e-05 22.4 0.3 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EAQ89295.1 - 0.0053 16.4 5.6 0.0053 16.4 3.9 2.4 1 1 1 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EAQ89295.1 - 0.0094 16.1 14.5 0.11 12.7 1.5 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Potex_coat PF06184.6 EAQ89295.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Potexvirus coat protein EamA PF00892.15 EAQ89295.1 - 0.72 9.8 24.7 0.057 13.4 2.4 3.9 3 1 1 4 4 4 0 EamA-like transporter family Sybindin PF04099.7 EAQ89296.1 - 7.4e-52 174.8 0.0 8.5e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EAQ89296.1 - 4.4e-09 36.3 0.1 9.4e-09 35.2 0.0 1.5 2 1 1 3 3 3 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 EAQ89297.1 - 2.4e-13 50.5 0.0 3.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EAQ89297.1 - 9.6e-06 25.3 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EAQ89297.1 - 6.1e-05 22.8 0.2 8.4e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EAQ89297.1 - 0.0004 19.7 1.4 0.0012 18.2 1.0 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 EAQ89298.1 - 9.5e-21 72.9 2.5 9.5e-21 72.9 1.8 1.6 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal SUI1 PF01253.17 EAQ89299.1 - 3.9e-22 77.8 0.4 8.2e-22 76.8 0.3 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EAQ89299.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV She9_MDM33 PF05546.6 EAQ89299.1 - 0.076 12.5 0.5 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family Methyltransf_11 PF08241.7 EAQ89300.1 - 4.1e-11 43.2 0.0 9.5e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ89300.1 - 0.0029 17.3 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ89300.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ89300.1 - 0.3 10.1 0.0 0.53 9.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-C2H2_4 PF13894.1 EAQ89301.1 - 0.079 13.3 32.8 0.11 12.9 0.0 7.2 7 0 0 7 7 7 0 C2H2-type zinc finger Peptidase_A24 PF01478.13 EAQ89301.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV leader peptidase family RCR PF12273.3 EAQ89303.1 - 0.0031 18.0 1.9 0.0041 17.6 1.3 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Neur_chan_memb PF02932.11 EAQ89303.1 - 0.022 14.6 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAP_N PF01213.14 EAQ89303.1 - 0.07 12.4 4.4 0.086 12.1 3.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EphA2_TM PF14575.1 EAQ89303.1 - 0.16 12.3 1.0 0.37 11.2 0.7 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EAQ89303.1 - 0.78 9.8 3.5 0.91 9.6 2.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2681 PF10883.3 EAQ89303.1 - 2.4 8.4 6.5 4.6 7.5 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) PAT1 PF09770.4 EAQ89303.1 - 4 5.5 13.2 4.3 5.4 9.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Metallophos PF00149.23 EAQ89304.1 - 2.1e-07 30.5 4.4 6.7e-07 28.8 3.1 1.9 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PBP1_TM PF14812.1 EAQ89304.1 - 0.025 14.8 12.3 0.022 15.0 3.2 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HPPK PF01288.15 EAQ89304.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) CDC45 PF02724.9 EAQ89304.1 - 0.81 7.6 4.8 1.8 6.4 3.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Polysacc_deac_1 PF01522.16 EAQ89305.1 - 3.9e-22 78.1 0.0 5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ank_5 PF13857.1 EAQ89306.1 - 0.0034 17.5 0.1 0.018 15.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ89306.1 - 0.0046 17.4 0.0 0.04 14.4 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EAQ89306.1 - 0.048 13.4 0.2 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.2 EAQ89306.1 - 0.052 13.8 0.0 0.34 11.2 0.0 2.1 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Cys_Met_Meta_PP PF01053.15 EAQ89307.1 - 1.6e-56 191.2 0.0 3.8e-56 190.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ofd1_CTDD PF10637.4 EAQ89309.1 - 3.5e-105 350.9 0.0 4.1e-98 327.7 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EAQ89309.1 - 2.8e-14 53.4 0.0 9.5e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EAQ89309.1 - 0.048 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.14 EAQ89310.1 - 1.3e-45 155.7 0.0 2.6e-45 154.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EAQ89310.1 - 2.3e-05 22.8 0.0 3.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Galanin PF01296.13 EAQ89310.1 - 0.016 15.0 0.2 0.053 13.3 0.1 1.9 1 0 0 1 1 1 0 Galanin Ribul_P_3_epim PF00834.14 EAQ89311.1 - 5.2e-65 218.3 0.0 9.9e-63 210.8 0.0 2.1 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EAQ89311.1 - 0.069 12.5 0.2 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF4243 PF14027.1 EAQ89312.1 - 8.4e-84 281.8 0.8 1e-83 281.5 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3885 PF13021.1 EAQ89312.1 - 0.054 13.2 0.7 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) COesterase PF00135.23 EAQ89313.1 - 1.1e-52 179.4 0.0 1.5e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ89313.1 - 0.00023 20.8 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.21 EAQ89315.1 - 0.0015 18.7 3.7 0.27 11.6 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ89315.1 - 0.0019 18.3 4.6 0.32 11.4 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ89315.1 - 0.0049 17.0 0.6 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-ribbon_3 PF13248.1 EAQ89315.1 - 0.038 13.2 0.3 0.064 12.4 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EAQ89315.1 - 0.065 13.1 2.5 6 6.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Cullin PF00888.17 EAQ89316.1 - 2.3e-48 165.1 0.0 3.9e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EAQ89316.1 - 2.4e-21 75.7 0.0 9.4e-21 73.8 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 EAQ89316.1 - 0.0091 15.6 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator zf-RING_2 PF13639.1 EAQ89317.1 - 3.7e-12 45.8 3.7 7.9e-12 44.8 2.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAQ89317.1 - 5.1e-12 45.7 0.4 1e-11 44.7 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAQ89317.1 - 6.4e-07 29.1 0.4 6.4e-07 29.1 0.2 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAQ89317.1 - 1.1e-06 28.5 3.4 2e-06 27.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ89317.1 - 1.5e-05 24.6 2.2 2.6e-05 23.8 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAQ89317.1 - 0.00017 21.1 2.4 0.00029 20.4 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ89317.1 - 0.00019 21.0 1.4 0.00032 20.3 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAQ89317.1 - 0.00034 20.2 1.0 0.001 18.7 0.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Baculo_RING PF05883.6 EAQ89317.1 - 0.0035 17.1 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 EAQ89317.1 - 0.0054 16.6 3.9 0.086 12.8 2.7 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain APH PF01636.18 EAQ89318.1 - 1.1e-44 152.9 0.2 1.1e-44 152.9 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EAQ89318.1 - 5.6e-05 22.4 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EAQ89318.1 - 0.0069 15.7 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 EAQ89318.1 - 0.011 14.7 0.0 0.053 12.5 0.0 2.0 2 1 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 EAQ89318.1 - 0.13 10.9 0.0 1.2 7.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Rad17 PF03215.10 EAQ89319.1 - 6.3e-53 180.2 0.0 2.5e-52 178.2 0.0 1.8 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EAQ89319.1 - 0.0053 16.4 0.0 0.017 14.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAQ89319.1 - 0.0089 15.6 0.1 0.043 13.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ89319.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ89319.1 - 0.016 15.2 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAQ89319.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EAQ89319.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EAQ89319.1 - 0.038 12.8 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EAQ89319.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EAQ89319.1 - 0.11 13.3 0.0 0.29 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ89319.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Daxx PF03344.10 EAQ89320.1 - 0.69 8.3 18.2 0.97 7.8 12.6 1.1 1 0 0 1 1 1 0 Daxx Family Pkr1 PF08636.5 EAQ89322.1 - 4.7e-37 125.9 3.2 6.3e-37 125.4 2.2 1.2 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.8 EAQ89322.1 - 0.13 12.6 1.4 0.6 10.5 0.3 2.3 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain LSM PF01423.17 EAQ89323.1 - 6.9e-16 57.5 0.0 9e-16 57.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAQ89323.1 - 0.0004 20.2 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EAQ89323.1 - 0.14 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF2763 PF10961.3 EAQ89323.1 - 0.54 10.6 6.6 0.89 9.9 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Methyltransf_26 PF13659.1 EAQ89324.1 - 4.7e-18 65.3 0.5 7.6e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ89324.1 - 0.043 13.1 0.0 4.2 6.7 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase small domain Med3 PF11593.3 EAQ89324.1 - 0.22 10.7 0.6 0.32 10.2 0.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PKD_channel PF08016.7 EAQ89325.1 - 0.031 12.7 7.7 0.38 9.1 1.1 2.2 2 0 0 2 2 2 0 Polycystin cation channel Mt_ATP-synt_B PF05405.9 EAQ89326.1 - 2.8e-55 186.2 9.7 3.4e-55 185.9 6.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EAQ89326.1 - 0.023 14.5 0.5 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF3549 PF12069.3 EAQ89326.1 - 0.068 11.9 5.4 0.11 11.3 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Orthopox_A5L PF06193.6 EAQ89326.1 - 0.21 11.5 3.1 0.11 12.4 0.2 1.8 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF724 PF05266.9 EAQ89326.1 - 0.32 10.5 7.6 0.57 9.7 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Rep_trans PF02486.14 EAQ89326.1 - 0.47 9.9 3.3 0.48 9.8 1.4 1.6 1 1 0 1 1 1 0 Replication initiation factor DUF4207 PF13904.1 EAQ89326.1 - 6.8 5.9 11.0 12 5.2 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) CBF PF03914.12 EAQ89327.1 - 1.5e-44 151.3 0.0 3.8e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family RasGEF_N PF00618.15 EAQ89327.1 - 0.0052 16.8 0.2 0.3 11.2 0.1 2.8 2 1 1 3 3 3 1 RasGEF N-terminal motif DUF3549 PF12069.3 EAQ89327.1 - 0.017 13.8 0.9 0.03 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) DUF2115 PF09888.4 EAQ89327.1 - 0.058 13.4 1.1 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Collagen PF01391.13 EAQ89328.1 - 0.0061 16.0 1.1 0.0061 16.0 0.8 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) bZIP_1 PF00170.16 EAQ89329.1 - 1.2e-08 34.8 14.2 2.2e-08 33.9 5.5 2.6 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ89329.1 - 4e-07 29.7 5.7 4e-07 29.7 4.0 2.9 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EAQ89329.1 - 5.9e-06 26.4 11.8 5.9e-06 26.4 8.2 2.2 2 1 0 2 2 2 1 bZIP Maf transcription factor Med6 PF04934.9 EAQ89329.1 - 0.027 14.0 0.3 0.081 12.4 0.2 1.8 1 0 0 1 1 1 0 MED6 mediator sub complex component DUF724 PF05266.9 EAQ89329.1 - 0.75 9.3 12.6 1.6 8.2 8.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EAQ89329.1 - 3.2 7.5 7.8 3.4 7.4 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EAQ89329.1 - 3.3 6.6 13.0 6.3 5.7 9.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EAQ89329.1 - 3.6 7.1 12.6 2.2 7.8 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF342 PF03961.8 EAQ89329.1 - 5.3 5.3 10.5 9.4 4.5 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sel1 PF08238.7 EAQ89332.1 - 1.1e-11 44.9 0.1 0.16 12.6 0.0 4.5 4 0 0 4 4 4 3 Sel1 repeat WD40 PF00400.27 EAQ89334.1 - 5.8e-58 190.8 16.4 7.9e-09 35.0 0.1 9.5 10 0 0 10 10 10 8 WD domain, G-beta repeat Utp12 PF04003.7 EAQ89334.1 - 7.2e-21 74.1 0.4 1.3e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EAQ89334.1 - 3e-05 22.9 2.6 0.1 11.2 0.2 4.9 1 1 2 4 4 4 2 Nup133 N terminal like P34-Arc PF04045.9 EAQ89335.1 - 1.4e-74 250.4 0.5 4e-65 219.4 0.0 2.1 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc Pyr_redox_3 PF13738.1 EAQ89336.1 - 5.5e-11 42.9 1.1 0.00018 21.6 0.0 4.0 3 1 2 5 5 5 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ89336.1 - 1.5e-05 24.8 0.0 4.7e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EAQ89336.1 - 0.0024 16.8 1.5 0.29 9.9 0.1 3.3 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAQ89336.1 - 0.0041 17.0 0.2 0.11 12.3 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ89336.1 - 0.0043 16.8 2.2 0.025 14.3 0.1 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EAQ89336.1 - 0.0048 15.4 0.0 0.0077 14.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EAQ89336.1 - 0.017 13.9 0.1 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EAQ89336.1 - 0.018 13.9 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ89336.1 - 0.023 13.7 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.14 EAQ89336.1 - 0.036 12.2 0.6 2.9 5.9 0.0 2.7 1 1 2 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EAQ89336.1 - 0.046 12.8 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EAQ89336.1 - 0.16 10.7 0.1 0.3 9.9 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A zf-CCCH PF00642.19 EAQ89337.1 - 1 9.0 7.5 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_beta PF02270.10 EAQ89338.1 - 1.9e-41 142.6 0.0 2.2e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit HAD PF12710.2 EAQ89339.1 - 1.4e-15 57.9 0.0 2.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EAQ89339.1 - 0.0046 16.1 0.0 0.81 8.8 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 EAQ89339.1 - 0.01 16.2 0.3 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ89339.1 - 0.038 13.5 1.5 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EAQ89339.1 - 0.18 11.0 0.3 0.62 9.3 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase SNase PF00565.12 EAQ89340.1 - 5e-20 71.7 0.0 9.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Reg_prop PF07494.6 EAQ89341.1 - 0.0048 16.7 0.0 1.7 8.9 0.0 3.2 2 0 0 2 2 2 1 Two component regulator propeller Kelch_6 PF13964.1 EAQ89341.1 - 0.016 15.3 2.8 0.23 11.6 0.0 3.4 4 0 0 4 4 4 0 Kelch motif DUF1668 PF07893.8 EAQ89341.1 - 0.13 11.4 0.1 0.79 8.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) BESS PF02944.15 EAQ89344.1 - 0.099 12.2 0.1 1 8.9 0.0 2.0 2 0 0 2 2 2 0 BESS motif zf-H2C2_2 PF13465.1 EAQ89345.1 - 9.6e-11 41.4 11.0 4e-05 23.6 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ89345.1 - 4.1e-10 39.3 10.0 2.1e-05 24.5 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ89345.1 - 1.7e-07 31.0 7.1 0.00022 21.3 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EAQ89345.1 - 6e-06 26.2 1.5 2.1e-05 24.5 1.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAQ89345.1 - 6.7e-06 25.8 6.2 0.0044 16.8 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ89345.1 - 3.3e-05 23.8 4.0 0.00013 21.9 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAQ89345.1 - 0.054 13.6 0.3 0.054 13.6 0.2 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAP2 PF01569.16 EAQ89345.1 - 0.056 13.1 0.4 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 PAP2 superfamily zf-C2HC_2 PF13913.1 EAQ89345.1 - 0.76 9.5 3.3 10 5.9 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EAQ89345.1 - 0.84 9.4 3.7 0.59 9.9 0.3 2.1 2 0 0 2 2 2 0 BED zinc finger SF3b1 PF08920.5 EAQ89346.1 - 6.8e-39 133.2 2.3 2.5e-38 131.3 0.0 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EAQ89346.1 - 2.4e-14 53.3 4.2 0.01 16.1 0.0 7.4 6 3 2 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 EAQ89346.1 - 9.1e-11 41.9 1.0 0.34 11.4 0.0 7.5 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EAQ89346.1 - 1.2e-09 37.4 10.2 0.96 9.7 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EAQ89346.1 - 2.5e-06 27.7 0.3 0.46 10.9 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EAQ89346.1 - 0.00075 17.9 0.3 0.097 10.9 0.1 3.0 2 2 1 3 3 3 1 Adaptin N terminal region UPF0236 PF06782.6 EAQ89346.1 - 0.0013 17.2 0.1 0.0021 16.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 EAQ89346.1 - 0.012 15.0 1.2 5.3 6.3 0.0 4.0 5 0 0 5 5 5 0 NUC173 domain CLASP_N PF12348.3 EAQ89346.1 - 0.012 14.9 0.4 1.3 8.3 0.0 3.6 4 1 0 4 4 4 0 CLASP N terminal HECT_2 PF09814.4 EAQ89347.1 - 6e-30 104.1 1.0 7.7e-30 103.7 0.7 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding OGG_N PF07934.7 EAQ89348.1 - 1.4e-21 76.6 0.0 3.5e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EAQ89348.1 - 1.9e-13 50.6 0.0 2.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EAQ89348.1 - 0.012 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif AflR PF08493.5 EAQ89348.1 - 5.1 6.0 8.5 2 7.3 3.2 1.9 2 0 0 2 2 2 0 Aflatoxin regulatory protein RRM_1 PF00076.17 EAQ89349.1 - 2.8e-30 103.7 0.3 2.2e-12 46.4 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89349.1 - 6.2e-23 80.5 0.0 2.5e-07 30.5 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89349.1 - 4.2e-15 55.3 0.3 3e-07 30.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S13_N PF08069.7 EAQ89350.1 - 1.1e-29 102.0 0.1 2.2e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EAQ89350.1 - 1.4e-22 79.2 0.0 2.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EAQ89350.1 - 0.037 13.7 0.1 0.094 12.4 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.8 EAQ89351.1 - 8.8e-06 25.1 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Med13_N PF11597.3 EAQ89351.1 - 0.55 8.8 6.7 0.68 8.5 4.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal vMSA PF00695.14 EAQ89351.1 - 0.76 8.9 11.8 0.9 8.6 8.2 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus CDC27 PF09507.5 EAQ89351.1 - 3.2 6.8 9.4 3.8 6.6 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Trs65 PF12735.2 EAQ89351.1 - 4 6.6 7.1 4.8 6.4 4.9 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 VRR_NUC PF08774.6 EAQ89352.1 - 2.7e-18 65.8 0.0 9.4e-18 64.0 0.0 1.9 2 0 0 2 2 2 1 VRR-NUC domain Apt1 PF10351.4 EAQ89353.1 - 1.9 7.2 5.1 2.6 6.8 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CBFB_NFYA PF02045.10 EAQ89355.1 - 7.2e-30 103.3 4.3 1.4e-29 102.4 3.0 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LSM PF01423.17 EAQ89356.1 - 1.2e-15 56.7 1.1 1.6e-15 56.3 0.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAQ89356.1 - 0.0024 17.7 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EAQ89356.1 - 0.038 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) HTH_25 PF13413.1 EAQ89356.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain DRMBL PF07522.9 EAQ89357.1 - 7.5e-13 48.4 0.0 1.6e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EAQ89357.1 - 2.4e-09 36.9 0.1 4.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain eIF-3_zeta PF05091.7 EAQ89358.1 - 6.2e-199 661.9 0.0 7.4e-199 661.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EAQ89358.1 - 0.0012 18.3 0.1 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF569) Pkinase PF00069.20 EAQ89362.1 - 5.8e-64 215.7 0.0 4.9e-40 137.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89362.1 - 2.3e-26 92.4 0.1 3.1e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EAQ89362.1 - 8.1e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EAQ89362.1 - 7e-08 31.7 0.0 1.1e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EAQ89362.1 - 4.7e-06 26.5 0.0 0.0062 16.2 0.1 2.7 1 1 0 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 EAQ89362.1 - 0.00081 19.7 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EAQ89362.1 - 0.002 17.9 0.1 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold Kdo PF06293.9 EAQ89362.1 - 0.013 14.5 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EAQ89362.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.19 EAQ89363.1 - 3.8e-23 81.7 26.5 3.3e-13 49.0 7.1 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter HTH_psq PF05225.11 EAQ89364.1 - 1.6e-06 27.5 0.3 3.2e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_1 PF03184.14 EAQ89364.1 - 0.0029 16.7 0.1 0.15 11.1 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ89364.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain BrkDBD PF09607.5 EAQ89364.1 - 0.11 12.0 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain Zn_clus PF00172.13 EAQ89365.1 - 0.21 11.5 1.1 0.35 10.8 0.8 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EAQ89370.1 - 2.7e-25 89.1 0.0 3.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ89370.1 - 1.1e-09 37.6 0.0 3.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAQ89370.1 - 1.1e-08 34.3 3.1 1e-06 27.8 0.2 3.1 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EAQ89370.1 - 4.2e-06 25.8 0.1 4.2e-06 25.8 0.1 2.1 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EAQ89370.1 - 0.00014 20.6 0.0 0.079 11.6 0.3 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Gln-synt_C PF00120.19 EAQ89371.1 - 8.1e-56 189.0 0.0 9.8e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EAQ89371.1 - 1.1e-18 66.5 0.0 1.8e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain CHZ PF09649.5 EAQ89372.1 - 0.029 13.5 0.0 0.081 12.1 0.0 1.8 2 0 0 2 2 2 0 Histone chaperone domain CHZ Protoglobin PF11563.3 EAQ89373.1 - 3.6e-58 195.6 0.2 4.3e-58 195.4 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Lactamase_B_2 PF12706.2 EAQ89374.1 - 4.6e-26 91.5 0.0 5.6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAQ89374.1 - 3.7e-15 56.0 0.0 4.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA PF00004.24 EAQ89376.1 - 5e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ89376.1 - 7.9e-08 32.4 0.0 6.4e-06 26.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EAQ89376.1 - 1.5e-06 28.2 0.0 7.7e-06 25.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAQ89376.1 - 1.8e-06 27.7 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAQ89376.1 - 2.8e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EAQ89376.1 - 7.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EAQ89376.1 - 0.00019 20.4 0.0 0.00058 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EAQ89376.1 - 0.00033 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EAQ89376.1 - 0.00076 20.2 0.5 0.0023 18.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EAQ89376.1 - 0.00079 19.7 0.2 0.0081 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAQ89376.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EAQ89376.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EAQ89376.1 - 0.0019 18.0 0.0 0.0063 16.3 0.0 1.9 3 0 0 3 3 1 1 AAA domain IstB_IS21 PF01695.12 EAQ89376.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAQ89376.1 - 0.0031 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAQ89376.1 - 0.0049 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EAQ89376.1 - 0.0053 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 EAQ89376.1 - 0.0072 16.2 0.7 0.017 15.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Sigma54_activat PF00158.21 EAQ89376.1 - 0.0074 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EAQ89376.1 - 0.0093 15.3 0.5 0.047 13.0 0.1 2.3 2 1 1 3 3 2 1 AAA domain AAA_3 PF07726.6 EAQ89376.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EAQ89376.1 - 0.019 14.8 0.1 0.063 13.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EAQ89376.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EAQ89376.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EAQ89376.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EAQ89376.1 - 0.025 14.1 0.3 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EAQ89376.1 - 0.028 14.1 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 EAQ89376.1 - 0.029 13.5 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EAQ89376.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EAQ89376.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain eIF-1a PF01176.14 EAQ89376.1 - 0.044 13.1 0.1 0.085 12.2 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 UPF0079 PF02367.12 EAQ89376.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EAQ89376.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EAQ89376.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DAP3 PF10236.4 EAQ89376.1 - 0.12 11.3 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.1 EAQ89376.1 - 0.59 10.4 6.5 2.8 8.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain SIS PF01380.17 EAQ89377.1 - 1e-55 186.9 0.1 6.1e-30 103.5 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EAQ89377.1 - 2.9e-25 88.7 0.0 2.8e-18 65.7 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EAQ89377.1 - 6.3e-20 71.4 0.0 1.6e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EAQ89377.1 - 1.2e-11 44.4 0.0 2.8e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EAQ89377.1 - 1.9e-06 26.7 0.1 3.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EAQ89377.1 - 0.0029 17.3 0.1 0.32 10.6 0.0 2.6 2 0 0 2 2 2 1 SIS domain Proteasome PF00227.21 EAQ89378.1 - 2e-24 85.9 0.0 2.6e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EAQ89379.1 - 5.8e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein PhzC-PhzF PF02567.11 EAQ89379.1 - 0.035 13.3 0.2 0.061 12.5 0.1 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein DUF3712 PF12505.3 EAQ89380.1 - 5.5e-25 87.8 1.0 1.2e-24 86.6 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) SP_C-Propep PF08999.5 EAQ89380.1 - 0.0052 16.2 0.6 0.0097 15.3 0.5 1.4 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide FMN_dh PF01070.13 EAQ89381.1 - 3.1e-101 338.7 0.1 3.9e-101 338.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EAQ89381.1 - 8.5e-20 70.3 0.0 2.4e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EAQ89381.1 - 1.2e-06 27.6 0.0 0.00038 19.4 0.0 3.0 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EAQ89381.1 - 9.7e-06 24.7 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EAQ89381.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ATP11 PF06644.6 EAQ89381.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 ATP11 protein Lipase_GDSL_2 PF13472.1 EAQ89382.1 - 7.1e-23 81.6 0.0 8.6e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ89382.1 - 1.2e-07 31.7 0.1 0.00024 21.0 0.0 2.2 1 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase PCI PF01399.22 EAQ89383.1 - 4.9e-11 42.8 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 EAQ89383.1 - 1.1 10.0 6.4 47 5.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3129 PF11327.3 EAQ89384.1 - 2.9e-69 232.6 0.5 3.7e-69 232.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) DnaJ PF00226.26 EAQ89385.1 - 8.5e-06 25.4 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 EAQ89387.1 - 0.079 12.7 0.2 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Double zinc ribbon SNF2_N PF00176.18 EAQ89390.1 - 1.2e-29 103.1 0.0 2.1e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EAQ89390.1 - 0.16 11.7 0.0 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF655 PF04919.7 EAQ89390.1 - 0.35 10.5 0.0 0.66 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Asn_synthase PF00733.16 EAQ89391.1 - 3.5e-36 125.0 0.0 5.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.1 EAQ89391.1 - 1.1e-25 90.1 0.0 2.8e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EAQ89391.1 - 2.8e-24 85.2 0.0 4.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Peptidase_S28 PF05577.7 EAQ89394.1 - 4.5e-47 160.5 0.0 3.4e-46 157.7 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EAQ89394.1 - 0.0077 16.1 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NAD_binding_6 PF08030.7 EAQ89395.1 - 9.6e-16 58.0 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EAQ89395.1 - 9.8e-07 29.3 0.0 3.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EAQ89395.1 - 0.012 15.4 0.0 0.036 13.9 0.0 1.9 1 1 0 1 1 1 0 FAD-binding domain Ctr PF04145.10 EAQ89396.1 - 2.7e-40 137.7 0.2 5.4e-40 136.7 0.1 1.5 1 0 0 1 1 1 1 Ctr copper transporter family Amidase PF01425.16 EAQ89397.1 - 1.4e-33 116.4 0.2 2.2e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 Amidase F-box-like PF12937.2 EAQ89398.1 - 0.0088 15.7 0.1 0.03 14.0 0.0 2.0 2 1 0 2 2 2 1 F-box-like Nro1 PF12753.2 EAQ89398.1 - 0.12 11.3 2.0 0.23 10.3 1.4 1.4 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF2457 PF10446.4 EAQ89398.1 - 0.85 8.2 17.8 0.29 9.8 9.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EAQ89398.1 - 7.4 6.3 9.8 11 5.7 4.6 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal RTA1 PF04479.8 EAQ89399.1 - 3.7e-08 33.1 4.9 0.00025 20.6 0.7 2.4 1 1 1 2 2 2 2 RTA1 like protein Fungal_trans_2 PF11951.3 EAQ89400.1 - 1.3e-16 60.2 0.0 1.8e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ89400.1 - 2.7e-05 23.9 5.5 2.7e-05 23.9 3.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_12 PF07740.7 EAQ89402.1 - 0.0013 19.1 5.4 0.0017 18.7 3.7 1.2 1 0 0 1 1 1 1 Ion channel inhibitory toxin PIF PF05092.7 EAQ89402.1 - 0.055 11.8 0.8 0.054 11.8 0.6 1.1 1 0 0 1 1 1 0 Per os infectivity Toxin_21 PF08091.6 EAQ89402.1 - 0.33 10.7 4.8 0.45 10.2 3.3 1.2 1 0 0 1 1 1 0 Spider insecticidal peptide WAP PF00095.16 EAQ89402.1 - 0.34 10.9 4.2 0.43 10.5 2.9 1.2 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Squash PF00299.13 EAQ89402.1 - 2.5 7.9 7.3 0.44 10.4 2.7 1.5 2 0 0 2 2 2 0 Squash family serine protease inhibitor Pkinase PF00069.20 EAQ89403.1 - 0.029 13.5 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RVT_2 PF07727.9 EAQ89405.1 - 5.7e-50 169.5 0.1 2.3e-47 161.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EAQ89405.1 - 0.00065 19.1 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EAQ89405.1 - 0.017 15.4 0.2 0.053 13.8 0.2 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glycos_transf_2 PF00535.21 EAQ89406.1 - 0.047 13.3 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 adh_short PF00106.20 EAQ89407.1 - 1.7e-21 76.8 1.5 2.7e-21 76.1 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ89407.1 - 3e-12 46.8 0.0 4.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ89407.1 - 3e-09 36.8 0.3 4.9e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 KR domain RVT_1 PF00078.22 EAQ89408.1 - 2.8e-31 108.5 0.0 3.8e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.1 EAQ89410.1 - 1.3e-26 93.4 2.8 3.2e-22 79.1 0.2 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ89410.1 - 8.8e-17 61.0 0.3 1.2e-07 31.0 0.0 3.3 2 2 1 3 3 3 3 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ89410.1 - 0.00023 21.2 0.0 0.00066 19.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ89410.1 - 0.0026 15.6 0.0 0.0037 15.0 0.0 1.1 1 0 0 1 1 1 1 Helicase Nif11 PF07862.6 EAQ89410.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function RVT_1 PF00078.22 EAQ89411.1 - 2.6e-27 95.5 0.0 3.8e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMG_box PF00505.14 EAQ89411.1 - 0.14 12.4 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box Ank_3 PF13606.1 EAQ89412.1 - 2.1e-05 24.3 0.0 0.002 18.2 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EAQ89412.1 - 8.7e-05 22.7 0.0 0.0021 18.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ89412.1 - 0.00072 19.2 0.0 0.0041 16.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EAQ89412.1 - 0.0033 17.6 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PAP2_3 PF14378.1 EAQ89413.1 - 1.4e-23 83.4 8.3 1.6e-19 70.1 3.0 2.6 2 1 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.16 EAQ89413.1 - 0.00048 19.8 3.7 0.0013 18.3 2.6 1.9 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EAQ89413.1 - 0.059 13.6 1.8 0.088 13.0 0.1 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF3328 PF11807.3 EAQ89415.1 - 2.8e-35 121.9 0.2 3.5e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.13 EAQ89416.1 - 6.7e-32 110.6 0.0 9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAQ89416.1 - 8.4e-06 26.3 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ89416.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Sigma70_r4 PF04545.11 EAQ89416.1 - 0.009 15.3 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Methyltransf_12 PF08242.7 EAQ89416.1 - 0.03 14.8 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EAQ89416.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 EAQ89416.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain BatA PF07584.6 EAQ89417.1 - 0.13 12.4 3.4 0.78 9.9 0.3 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal VWA_3 PF13768.1 EAQ89418.1 - 7.9e-26 90.5 0.0 1.5e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EAQ89418.1 - 5.2e-21 74.5 0.0 1.2e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EAQ89418.1 - 7.6e-10 39.1 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EAQ89418.1 - 1.4e-07 31.3 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EAQ89418.1 - 2.3e-07 30.1 0.0 6e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EAQ89418.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Ribosomal_60s PF00428.14 EAQ89418.1 - 0.056 13.8 4.5 0.83 10.0 0.3 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Imp-YgjV PF10688.4 EAQ89419.1 - 0.0085 15.5 0.6 0.012 15.0 0.4 1.1 1 0 0 1 1 1 1 Bacterial inner membrane protein ADH_zinc_N PF00107.21 EAQ89420.1 - 4.2e-08 32.7 0.2 8e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ89420.1 - 2.6e-07 30.3 0.0 5.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Colicin_V PF02674.11 EAQ89421.1 - 0.014 15.2 0.3 0.014 15.2 0.2 1.8 2 0 0 2 2 2 0 Colicin V production protein TP53IP5 PF15331.1 EAQ89424.1 - 2.1 8.1 6.7 0.32 10.8 0.6 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Zn_clus PF00172.13 EAQ89425.1 - 1.1e-07 31.6 5.9 1.1e-07 31.6 4.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EAQ89426.1 - 2.7e-26 92.4 3.3 4.4e-26 91.7 2.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ89426.1 - 1.9e-09 37.4 1.6 5.3e-09 35.9 1.0 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ89426.1 - 8.7e-09 35.4 0.8 7.6e-08 32.4 0.6 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF3236 PF11576.3 EAQ89426.1 - 0.0018 17.6 1.1 0.0038 16.6 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3236) Eno-Rase_NADH_b PF12242.3 EAQ89426.1 - 0.0066 16.2 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 EAQ89426.1 - 1.1 8.9 5.7 4.9 6.7 3.9 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein IU_nuc_hydro PF01156.14 EAQ89427.1 - 1e-05 24.8 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase APH PF01636.18 EAQ89428.1 - 2e-05 24.4 8.5 5.3e-05 23.0 5.8 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ89428.1 - 0.0072 15.9 0.1 0.067 12.7 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Zn_clus PF00172.13 EAQ89431.1 - 0.01 15.7 15.1 0.013 15.4 7.4 2.7 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EAQ89431.1 - 0.041 12.8 5.3 0.064 12.2 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.11 EAQ89431.1 - 0.21 10.8 2.8 0.32 10.2 1.9 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.9 EAQ89431.1 - 6.1 6.1 12.0 13 5.0 8.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AMP-binding PF00501.23 EAQ89433.1 - 1.6e-59 201.3 0.2 4.5e-42 143.9 0.0 2.6 2 1 1 3 3 3 2 AMP-binding enzyme Condensation PF00668.15 EAQ89433.1 - 2.8e-59 200.4 0.0 4.3e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain adh_short_C2 PF13561.1 EAQ89433.1 - 2.3e-36 125.7 0.0 3.9e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ89433.1 - 1.9e-27 96.2 7.6 5.1e-26 91.5 2.9 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAQ89433.1 - 1.3e-11 44.4 4.9 1.7e-10 40.8 1.7 2.4 2 0 0 2 2 2 1 KR domain PP-binding PF00550.20 EAQ89433.1 - 3.9e-10 39.8 0.0 1.5e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EAQ89433.1 - 1.8e-08 34.6 0.0 5.1e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EAQ89433.1 - 1.3e-05 26.0 0.4 0.00015 22.6 0.0 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Eno-Rase_NADH_b PF12242.3 EAQ89433.1 - 0.051 13.3 0.4 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F-box-like PF12937.2 EAQ89435.1 - 9.5e-09 34.8 0.1 2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ89435.1 - 0.077 12.6 0.1 0.28 10.9 0.1 2.0 1 1 0 1 1 1 0 F-box domain DNase_II PF03265.10 EAQ89435.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Deoxyribonuclease II Toxin_53 PF15532.1 EAQ89436.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 53 Pox_T4_N PF04491.7 EAQ89436.1 - 0.077 12.8 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus F-box-like PF12937.2 EAQ89437.1 - 0.024 14.3 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like Dimer_Tnp_hAT PF05699.9 EAQ89438.1 - 2.8e-16 58.9 0.2 4.2e-16 58.3 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exo_endo_phos_2 PF14529.1 EAQ89439.1 - 4.4e-13 48.8 0.0 2e-12 46.7 0.0 2.1 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ89439.1 - 3.4e-09 37.0 0.1 8.5e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_61 PF03443.9 EAQ89440.1 - 2.2e-42 145.3 0.2 3e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ89440.1 - 3.6e-13 48.9 14.3 3.6e-13 48.9 9.9 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Helicase_C PF00271.26 EAQ89442.1 - 3.1e-08 33.3 0.1 6.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ89442.1 - 8e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ89442.1 - 0.00024 20.9 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_jaz PF12171.3 EAQ89443.1 - 0.0021 18.1 7.1 0.29 11.3 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EAQ89443.1 - 0.0064 16.7 4.8 0.0064 16.7 3.3 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ89443.1 - 0.0091 16.2 16.4 0.043 14.1 0.4 4.5 3 1 1 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ89443.1 - 0.033 14.5 1.3 0.033 14.5 0.9 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger FG-GAP PF01839.18 EAQ89443.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 FG-GAP repeat zf-met PF12874.2 EAQ89443.1 - 0.11 12.7 3.6 1.7 8.9 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_clus PF00172.13 EAQ89443.1 - 0.67 9.9 17.9 0.071 13.0 7.1 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF629 PF04780.7 EAQ89443.1 - 5 5.5 3.8 18 3.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) F-box-like PF12937.2 EAQ89444.1 - 0.026 14.2 0.1 0.098 12.4 0.1 2.1 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EAQ89446.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Glyco_hydro_2_N PF02837.13 EAQ89447.1 - 2.2e-27 95.6 0.0 3.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EAQ89447.1 - 5.4e-10 39.7 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EAQ89447.1 - 0.00013 20.9 0.2 0.00037 19.4 0.1 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain FAD_binding_3 PF01494.14 EAQ89448.1 - 2.4e-30 105.8 0.0 5.9e-30 104.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ89448.1 - 1.3e-05 24.2 0.0 0.069 12.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EAQ89448.1 - 5.5e-05 22.4 0.8 0.012 14.6 0.2 2.5 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ89448.1 - 0.00015 21.7 0.1 0.00036 20.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ89448.1 - 0.00055 20.0 0.0 0.0065 16.5 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ89448.1 - 0.0074 16.6 0.5 0.35 11.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ89448.1 - 0.05 12.4 0.0 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EAQ89448.1 - 0.096 11.5 0.1 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 EAQ89448.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1515 PF07439.6 EAQ89450.1 - 0.11 12.2 1.1 0.3 10.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Amidoligase_2 PF12224.3 EAQ89452.1 - 8.3e-13 48.5 0.0 9.4e-09 35.2 0.0 2.3 1 1 0 2 2 2 2 Putative amidoligase enzyme Nop14 PF04147.7 EAQ89453.1 - 5.2 4.8 17.7 0.41 8.5 1.2 2.1 2 0 0 2 2 2 0 Nop14-like family CBM_1 PF00734.13 EAQ89456.1 - 3.4e-12 45.8 16.1 1.1e-11 44.1 11.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EAQ89456.1 - 2.1e-06 27.1 0.0 1.5e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ89456.1 - 3.7e-06 26.7 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ89456.1 - 0.00014 21.8 0.0 0.024 14.4 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase_phd PF10503.4 EAQ89456.1 - 0.00024 20.4 0.1 0.0013 18.0 0.1 1.9 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 EAQ89456.1 - 0.0013 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.9 EAQ89456.1 - 0.0044 16.2 0.0 0.01 15.0 0.0 1.5 1 1 1 2 2 2 1 Secretory lipase Esterase PF00756.15 EAQ89456.1 - 0.01 15.2 0.5 0.034 13.5 0.4 1.8 1 1 0 1 1 1 0 Putative esterase DUF1275 PF06912.6 EAQ89457.1 - 2.9e-38 131.1 11.4 3.6e-38 130.8 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ada_Zn_binding PF02805.11 EAQ89457.1 - 0.078 12.5 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Metal binding domain of Ada Cupin_1 PF00190.17 EAQ89458.1 - 7.6e-31 106.4 0.0 1e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EAQ89458.1 - 2.1e-26 91.2 1.2 1.3e-13 50.2 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EAQ89458.1 - 2.1e-09 36.6 0.0 0.00093 18.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EAQ89458.1 - 1.8e-08 34.1 0.2 0.00066 19.3 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EAQ89458.1 - 0.00013 21.6 0.0 0.079 12.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_6 PF12852.2 EAQ89458.1 - 0.00047 19.8 0.0 0.68 9.5 0.0 2.3 2 0 0 2 2 2 2 Cupin ARD PF03079.9 EAQ89458.1 - 0.0048 16.8 0.8 2 8.3 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family Cupin_7 PF12973.2 EAQ89458.1 - 0.019 14.7 0.2 0.49 10.2 0.0 2.9 2 1 1 3 3 3 0 ChrR Cupin-like domain 3-HAO PF06052.7 EAQ89458.1 - 0.022 14.2 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 EAQ89458.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) 2OG-FeII_Oxy_5 PF13759.1 EAQ89458.1 - 0.09 13.0 0.0 8.3 6.7 0.0 3.0 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase AAA PF00004.24 EAQ89459.1 - 3.1e-07 30.6 1.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ89459.1 - 0.093 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EAQ89459.1 - 0.23 11.2 0.4 0.54 10.0 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain FLO_LFY PF01698.11 EAQ89459.1 - 3.1 6.5 9.8 7 5.3 6.8 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein Methyltransf_23 PF13489.1 EAQ89460.1 - 4.5e-16 58.9 0.0 8.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ89460.1 - 0.00031 20.3 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ89460.1 - 0.13 12.7 0.0 4.1 7.9 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ89460.1 - 0.13 12.8 0.1 14 6.3 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain DUF4246 PF14033.1 EAQ89461.1 - 4.3e-171 569.9 0.0 5.4e-171 569.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.1 EAQ89461.1 - 0.061 13.8 0.1 0.25 11.8 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_hydro_11 PF00457.12 EAQ89463.1 - 4.2e-60 202.2 11.7 5e-60 201.9 8.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CHB_HEX_C_1 PF13290.1 EAQ89463.1 - 0.00061 19.5 0.2 0.0012 18.5 0.2 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain AAA_12 PF13087.1 EAQ89464.1 - 1.2e-35 122.7 0.0 2.5e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAQ89464.1 - 2.6e-25 89.3 1.6 2.9e-24 85.9 0.5 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ89464.1 - 6.2e-09 35.4 0.1 1.6e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAQ89464.1 - 2.3e-07 30.5 0.1 7.4e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.4 EAQ89464.1 - 0.014 14.4 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EAQ89464.1 - 0.029 13.5 0.0 0.067 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EAQ89464.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.27 EAQ89465.1 - 2.4e-11 43.0 0.5 0.011 15.6 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Pox_RNA_Pol_19 PF05320.7 EAQ89465.1 - 5.2 6.8 9.7 8.4 6.1 6.7 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit WD40 PF00400.27 EAQ89466.1 - 9.7e-33 110.8 1.6 5.6e-12 45.0 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat PUL PF08324.6 EAQ89467.1 - 2.5e-52 177.3 0.0 3.2e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EAQ89467.1 - 9.8e-44 148.0 0.2 2.3e-43 146.8 0.1 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EAQ89467.1 - 2.2e-34 116.0 12.1 2.8e-07 30.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat SRR1 PF07985.7 EAQ89469.1 - 0.024 14.5 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 SRR1 CDC45 PF02724.9 EAQ89470.1 - 0.034 12.1 2.6 0.051 11.6 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TATR PF03430.8 EAQ89470.1 - 1.4 7.5 4.5 2 6.9 3.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FLO_LFY PF01698.11 EAQ89471.1 - 0.17 10.6 4.9 0.17 10.7 3.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1777 PF08648.7 EAQ89471.1 - 0.56 9.9 11.5 0.59 9.8 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Sporozoite_P67 PF05642.6 EAQ89471.1 - 1.4 6.6 8.4 1.5 6.6 5.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sox_N PF12444.3 EAQ89471.1 - 2 9.5 6.5 2.3 9.3 4.5 1.1 1 0 0 1 1 1 0 Sox developmental protein N terminal Vfa1 PF08432.5 EAQ89471.1 - 2 8.3 10.0 2.1 8.3 7.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2956 PF11169.3 EAQ89471.1 - 2.4 8.1 4.9 2.3 8.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) MIP-T3 PF10243.4 EAQ89471.1 - 7.2 4.9 10.7 7.5 4.8 7.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Methyltransf_11 PF08241.7 EAQ89472.1 - 1.3e-10 41.5 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ89472.1 - 2.1e-10 40.3 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ89472.1 - 1.1e-07 31.6 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ89472.1 - 7.3e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ89472.1 - 0.0003 21.2 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ89472.1 - 0.00045 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EAQ89472.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ89472.1 - 0.024 15.2 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EAQ89472.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase Ifi-6-16 PF06140.8 EAQ89472.1 - 1 9.1 6.4 2.2 8.1 4.4 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family SH3BP5 PF05276.9 EAQ89473.1 - 0.068 12.4 0.7 0.093 12.0 0.5 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) IncA PF04156.9 EAQ89473.1 - 0.1 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 IncA protein REV PF00424.13 EAQ89473.1 - 0.54 10.1 3.1 0.39 10.6 1.0 1.5 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) bZIP_1 PF00170.16 EAQ89473.1 - 0.94 9.4 4.5 1.5 8.8 3.1 1.2 1 0 0 1 1 1 0 bZIP transcription factor Pyr_redox_3 PF13738.1 EAQ89474.1 - 2.7e-19 70.0 0.0 5.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ89474.1 - 6.2e-11 42.1 0.0 6.9e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ89474.1 - 1.5e-07 30.6 0.2 0.0038 16.1 0.0 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EAQ89474.1 - 2.7e-07 29.8 0.0 5.8e-05 22.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EAQ89474.1 - 2.5e-05 22.6 0.1 0.00012 20.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAQ89474.1 - 4.3e-05 23.4 0.0 0.00059 19.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ89474.1 - 0.00019 21.2 0.0 0.00096 18.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EAQ89474.1 - 0.0002 20.5 0.0 0.00053 19.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EAQ89474.1 - 0.0023 16.8 0.0 0.0079 15.1 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAQ89474.1 - 0.014 14.2 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EAQ89474.1 - 0.12 11.4 0.1 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Tyrosinase PF00264.15 EAQ89475.1 - 1.5e-44 152.7 1.2 2e-44 152.4 0.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1100 PF06500.6 EAQ89475.1 - 0.063 11.8 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) OHCU_decarbox PF09349.5 EAQ89475.1 - 0.21 11.8 0.0 0.32 11.2 0.0 1.2 1 0 0 1 1 1 0 OHCU decarboxylase HSDR_N_2 PF13588.1 EAQ89477.1 - 0.065 13.0 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) MAP7 PF05672.6 EAQ89477.1 - 0.065 12.6 19.4 0.1 11.9 13.5 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 EAQ89477.1 - 3.5 6.9 21.9 5 6.4 15.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SBF PF01758.11 EAQ89479.1 - 1.1e-48 165.0 14.9 1.1e-48 165.0 10.3 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family BBE PF08031.7 EAQ89480.1 - 0.0044 16.8 0.1 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 Berberine and berberine like FMN_red PF03358.10 EAQ89482.1 - 9.9e-21 73.8 0.0 1.5e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PAN_4 PF14295.1 EAQ89483.1 - 5.1e-05 22.8 4.7 0.00011 21.7 3.3 1.6 1 0 0 1 1 1 1 PAN domain DUF3999 PF13163.1 EAQ89483.1 - 0.08 11.8 0.1 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) PsbX PF06596.6 EAQ89483.1 - 4.9 6.9 6.7 9.4 6.0 4.6 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) NAD_binding_10 PF13460.1 EAQ89484.1 - 1.7e-10 41.2 0.0 2.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ89484.1 - 1.5e-08 34.3 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ89484.1 - 1.8e-05 23.8 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 EAQ89484.1 - 0.00089 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EAQ89484.1 - 0.0092 14.7 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAQ89484.1 - 0.023 14.5 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAQ89484.1 - 0.052 12.4 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain KdpA PF03814.10 EAQ89484.1 - 0.055 11.4 0.2 0.08 10.9 0.2 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit KR PF08659.5 EAQ89484.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 EAQ89484.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Myb_DNA-bind_6 PF13921.1 EAQ89485.1 - 2.2e-26 91.6 9.7 2.9e-15 56.1 0.5 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ89485.1 - 1.4e-23 82.7 11.0 7.9e-12 45.0 1.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rubis-subs-bind PF09273.6 EAQ89485.1 - 0.072 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Ferric_reduct PF01794.14 EAQ89486.1 - 6.4e-14 52.1 10.1 6.4e-14 52.1 7.0 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component zf-BED PF02892.10 EAQ89486.1 - 0.00063 19.4 0.4 0.0016 18.1 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger DUF4413 PF14372.1 EAQ89486.1 - 0.0012 18.8 0.1 1 9.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4413) FAD_binding_8 PF08022.7 EAQ89486.1 - 0.023 14.5 0.8 0.058 13.2 0.6 1.6 1 0 0 1 1 1 0 FAD-binding domain Vac7 PF12751.2 EAQ89486.1 - 0.4 9.4 3.6 0.86 8.3 0.0 2.7 3 0 0 3 3 3 0 Vacuolar segregation subunit 7 MFS_1 PF07690.11 EAQ89488.1 - 9.2e-21 73.9 31.5 3.2e-16 59.0 15.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EAQ89489.1 - 2.5e-10 40.6 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RVT_2 PF07727.9 EAQ89491.1 - 9.2e-53 178.7 0.1 7e-52 175.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EAQ89491.1 - 7.8e-08 31.8 0.1 1.6e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 EAQ89491.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3g PF12353.3 EAQ89492.1 - 0.011 15.6 1.1 0.011 15.6 0.8 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF2113 PF09886.4 EAQ89492.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) APH PF01636.18 EAQ89494.1 - 7.1e-05 22.6 1.2 0.00012 21.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ89494.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FPN1 PF06963.7 EAQ89496.1 - 7.5e-60 202.5 0.3 9.7e-60 202.1 0.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1_like PF12832.2 EAQ89496.1 - 0.025 14.3 1.1 0.14 11.9 0.0 2.5 2 1 1 3 3 3 0 MFS_1 like family DUF4233 PF14017.1 EAQ89496.1 - 2.6 8.0 6.8 3.6 7.5 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) UPF0182 PF03699.8 EAQ89496.1 - 4 5.2 6.0 0.3 8.9 0.7 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) zf-met PF12874.2 EAQ89497.1 - 0.0035 17.4 1.8 0.45 10.8 0.2 3.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EAQ89497.1 - 0.0066 16.7 14.5 2.4 8.6 0.8 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ89497.1 - 0.069 13.4 0.8 0.069 13.4 0.6 3.4 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ89497.1 - 0.34 11.3 11.8 7.4 7.1 0.4 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type Fungal_trans PF04082.13 EAQ89498.1 - 6.3e-25 87.5 2.2 1.2e-24 86.5 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ89498.1 - 2.3e-07 30.6 12.1 4.6e-07 29.6 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EAQ89498.1 - 1.1 7.3 15.3 1.5 6.9 10.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Brr6_like_C_C PF10104.4 EAQ89499.1 - 8.3e-42 141.8 0.0 1.1e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.6 EAQ89500.1 - 2.8e-12 45.9 0.0 4.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 EAQ89501.1 - 1.5e-41 142.2 0.4 1e-24 87.1 0.3 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89501.1 - 6.8e-15 54.8 0.4 2.5e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Cupin_1 PF00190.17 EAQ89502.1 - 9e-07 28.4 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EAQ89502.1 - 0.00012 21.5 0.0 0.00059 19.2 0.0 2.0 1 1 0 1 1 1 1 Cupin domain Glyco_hydro_61 PF03443.9 EAQ89503.1 - 7.5e-51 173.0 0.0 9.9e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 eIF3g PF12353.3 EAQ89505.1 - 0.0048 16.8 1.0 0.016 15.1 0.7 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2113 PF09886.4 EAQ89505.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) RVT_1 PF00078.22 EAQ89506.1 - 2.1e-20 73.0 0.0 4.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ89506.1 - 1.3e-13 51.0 0.2 4.7e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ89506.1 - 2.5e-09 36.6 2.4 6e-09 35.4 1.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IN_DBD_C PF00552.16 EAQ89506.1 - 0.013 14.9 2.2 0.061 12.7 0.2 2.6 2 0 0 2 2 2 0 Integrase DNA binding domain ATG16 PF08614.6 EAQ89507.1 - 0.00033 20.5 1.5 0.00083 19.2 1.0 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) zf-CCHC PF00098.18 EAQ89507.1 - 0.0014 18.4 0.1 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle AAA_13 PF13166.1 EAQ89507.1 - 0.0022 16.5 0.3 0.0022 16.5 0.2 1.5 2 0 0 2 2 2 1 AAA domain Uds1 PF15456.1 EAQ89507.1 - 0.003 17.5 3.0 0.56 10.2 0.1 3.1 3 1 0 3 3 3 2 Up-regulated During Septation SlyX PF04102.7 EAQ89507.1 - 0.014 15.7 1.1 0.044 14.1 0.4 2.2 1 1 1 2 2 2 0 SlyX Retrotrans_gag PF03732.12 EAQ89507.1 - 0.026 14.5 0.1 0.1 12.6 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein BRE1 PF08647.6 EAQ89507.1 - 0.059 13.3 0.3 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.6 EAQ89507.1 - 0.061 11.9 0.1 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 EAQ89507.1 - 0.14 11.8 0.7 0.29 10.7 0.5 1.5 1 0 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 EAQ89507.1 - 0.27 11.0 7.9 0.032 14.0 1.6 2.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 EAQ89507.1 - 0.63 9.6 6.6 0.3 10.7 2.1 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 RVT_2 PF07727.9 EAQ89508.1 - 1e-52 178.6 0.1 7.2e-52 175.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EAQ89508.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pec_lyase_C PF00544.14 EAQ89510.1 - 1.3e-42 145.5 5.5 2.2e-42 144.8 3.8 1.4 1 0 0 1 1 1 1 Pectate lyase LDB19 PF13002.2 EAQ89510.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Tmemb_170 PF10190.4 EAQ89511.1 - 0.13 12.2 0.3 0.19 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein 170 Alpha_GJ PF03229.8 EAQ89511.1 - 0.15 12.4 3.5 0.71 10.2 0.0 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J DUF3328 PF11807.3 EAQ89512.1 - 6e-43 147.0 0.9 3.6e-42 144.5 0.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CFEM PF05730.6 EAQ89514.1 - 2.6e-20 71.9 7.7 4.6e-20 71.2 5.3 1.4 1 0 0 1 1 1 1 CFEM domain FAD_binding_4 PF01565.18 EAQ89515.1 - 2.1e-14 53.1 3.3 3.5e-14 52.4 1.5 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAQ89515.1 - 4.6e-09 36.0 0.1 2.8e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Berberine and berberine like Tyrosinase PF00264.15 EAQ89518.1 - 7.2e-50 170.2 0.1 8.9e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DnaJ PF00226.26 EAQ89520.1 - 8.9e-19 66.9 2.1 8.9e-19 66.9 1.5 2.5 2 0 0 2 2 2 1 DnaJ domain DUF2803 PF10972.3 EAQ89520.1 - 1.5 8.2 7.1 1.1 8.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2803) RRM_1 PF00076.17 EAQ89521.1 - 1.8e-10 40.3 0.0 3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89521.1 - 2.8e-09 36.6 0.0 5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89521.1 - 2.8e-07 30.3 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAQ89521.1 - 0.00023 20.8 0.1 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EAQ89522.1 - 1.9e-28 98.1 0.5 3e-28 97.5 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EAQ89522.1 - 5.6e-21 74.8 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ89522.1 - 1.9e-17 63.2 0.0 3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ89522.1 - 1.5e-13 50.9 0.0 3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAQ89522.1 - 5.6e-13 48.5 0.2 8.1e-13 48.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAQ89522.1 - 1.7e-12 47.3 0.0 2.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ89522.1 - 3e-11 43.6 0.0 8.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ89522.1 - 1.4e-10 40.7 0.0 2.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EAQ89522.1 - 2.5e-10 40.9 0.0 6.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ89522.1 - 2e-09 37.4 0.0 5.3e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ89522.1 - 3.2e-05 23.3 0.0 5.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EAQ89522.1 - 0.00031 20.3 0.1 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EAQ89522.1 - 0.00072 18.7 0.1 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EAQ89522.1 - 0.00096 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EAQ89522.1 - 0.0029 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EAQ89522.1 - 0.028 15.2 0.0 0.1 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EAQ89522.1 - 0.038 13.0 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.6 EAQ89522.1 - 0.038 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Pox_MCEL PF03291.11 EAQ89522.1 - 0.039 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme Transket_pyr PF02779.19 EAQ89523.1 - 1.2e-45 155.1 0.0 1.7e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EAQ89523.1 - 1.3e-32 112.3 0.2 4.4e-32 110.6 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Spore_IV_A PF09547.5 EAQ89523.1 - 0.0052 15.5 0.0 0.0088 14.7 0.0 1.3 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) Glyco_hydro_61 PF03443.9 EAQ89525.1 - 4.1e-42 144.4 0.0 4.8e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AIG2_2 PF13772.1 EAQ89526.1 - 0.0002 21.4 0.1 0.0056 16.7 0.1 2.2 1 1 0 1 1 1 1 AIG2-like family SP2 PF03014.9 EAQ89526.1 - 0.02 12.8 0.3 0.027 12.3 0.2 1.1 1 0 0 1 1 1 0 Structural protein 2 AIG2 PF06094.7 EAQ89526.1 - 0.027 14.9 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family DUF914 PF06027.7 EAQ89527.1 - 6.2e-103 344.1 16.5 7.8e-103 343.8 11.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EAQ89527.1 - 2.3e-05 24.4 25.7 5.9e-05 23.0 6.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.2 EAQ89527.1 - 0.00081 18.4 0.7 0.00081 18.4 0.5 2.1 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS TPT PF03151.11 EAQ89527.1 - 8.1 6.0 22.6 0.88 9.1 3.9 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family CVNH PF08881.5 EAQ89529.1 - 2.2e-44 149.9 0.1 3.3e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 EAQ89529.1 - 7.8e-14 51.3 0.0 1.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.10 EAQ89529.1 - 4.3e-08 32.6 17.0 4.3e-08 32.6 11.8 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EAQ89529.1 - 0.00054 19.4 13.0 0.0013 18.2 9.0 1.7 1 0 0 1 1 1 1 YMGG-like Gly-zipper MIP-T3 PF10243.4 EAQ89529.1 - 0.012 14.0 19.7 0.019 13.4 13.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TraT PF05818.7 EAQ89529.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein CCDC71L PF15374.1 EAQ89529.1 - 0.14 11.4 6.5 0.19 11.0 4.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L RR_TM4-6 PF06459.7 EAQ89529.1 - 0.17 11.7 5.1 0.22 11.3 3.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 EAQ89529.1 - 0.24 10.3 1.9 0.32 9.9 1.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1510 PF07423.6 EAQ89529.1 - 0.4 10.0 12.1 0.69 9.2 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EAQ89529.1 - 0.46 8.1 6.5 0.55 7.8 4.5 1.0 1 0 0 1 1 1 0 Ycf1 Gly-zipper_Omp PF13488.1 EAQ89529.1 - 0.57 9.8 20.7 1.3 8.7 13.2 2.4 1 1 1 2 2 2 0 Glycine zipper CDC45 PF02724.9 EAQ89529.1 - 2 6.3 13.8 2.7 5.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF533 PF04391.7 EAQ89529.1 - 3 7.1 12.3 0.019 14.3 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF788 PF05620.6 EAQ89529.1 - 7.8 6.3 5.6 17 5.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) SH3_3 PF08239.6 EAQ89531.1 - 0.00074 19.6 0.5 0.0019 18.3 0.1 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 EAQ89531.1 - 0.038 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain PAP_assoc PF03828.14 EAQ89532.1 - 2.9e-19 68.7 0.1 7e-19 67.5 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Abhydrolase_1 PF00561.15 EAQ89534.1 - 2.1e-14 53.6 0.2 7.7e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ89534.1 - 4.4e-11 43.1 3.8 3.5e-10 40.1 2.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EAQ89534.1 - 7.3e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase MFS_1 PF07690.11 EAQ89536.1 - 2.3e-21 75.9 30.5 2.8e-17 62.4 12.2 3.6 2 1 2 4 4 4 2 Major Facilitator Superfamily malic PF00390.14 EAQ89536.1 - 0.22 11.0 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain LysM PF01476.15 EAQ89539.1 - 1.9e-05 24.4 0.0 0.28 11.1 0.0 3.3 3 0 0 3 3 3 2 LysM domain Glyco_hydro_43 PF04616.9 EAQ89540.1 - 1.7e-50 171.6 5.0 3.8e-50 170.5 3.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EAQ89540.1 - 1.9e-26 92.6 3.3 1.9e-26 92.6 2.3 2.5 2 1 1 3 3 3 1 Carbohydrate binding module (family 6) APH PF01636.18 EAQ89540.1 - 2.7e-05 24.0 0.2 5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_32N PF00251.15 EAQ89540.1 - 0.0074 15.6 4.6 0.013 14.8 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Choline_kinase PF01633.15 EAQ89540.1 - 0.046 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF192 PF02643.10 EAQ89544.1 - 0.16 11.6 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized ACR, COG1430 DUF3042 PF11240.3 EAQ89545.1 - 0.13 12.1 1.2 0.33 10.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) MiaE PF06175.6 EAQ89545.1 - 0.21 10.9 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) SIR2 PF02146.12 EAQ89546.1 - 4.4e-39 134.0 0.0 1.2e-34 119.5 0.0 2.3 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 EAQ89546.1 - 0.0034 17.1 0.5 1.1 8.9 0.0 3.2 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, central domain VRP3 PF03536.10 EAQ89546.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein DMPK_coil PF08826.5 EAQ89546.1 - 0.15 11.9 1.1 0.28 11.1 0.8 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like Cep57_CLD_2 PF14197.1 EAQ89546.1 - 0.23 11.4 1.8 0.43 10.5 1.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GCR1_C PF12550.3 EAQ89547.1 - 5.3e-23 80.6 0.6 1.1e-22 79.6 0.4 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 EAQ89547.1 - 2.5 8.3 0.0 2.5 8.3 0.0 3.8 4 2 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain Arginosuc_synth PF00764.14 EAQ89548.1 - 5.2e-100 335.2 0.0 5.9e-78 262.5 0.0 2.0 2 0 0 2 2 2 2 Arginosuccinate synthase Asn_synthase PF00733.16 EAQ89548.1 - 2.1e-05 24.1 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EAQ89548.1 - 0.0018 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EAQ89548.1 - 0.0058 15.2 0.0 0.0082 14.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAT1 PF09770.4 EAQ89549.1 - 2.2 6.3 33.7 2.9 6.0 23.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHA PF00498.21 EAQ89551.1 - 1.4e-16 60.2 0.1 2.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain CENP-Q PF13094.1 EAQ89551.1 - 0.72 9.8 24.3 0.78 9.7 5.2 2.9 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 EAQ89551.1 - 1.5 8.3 13.4 0.84 9.1 2.6 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uds1 PF15456.1 EAQ89551.1 - 1.6 8.7 12.9 0.09 12.7 3.5 2.7 1 1 1 2 2 2 0 Up-regulated During Septation Romo1 PF10247.4 EAQ89552.1 - 1.6e-09 37.7 1.4 1.9e-09 37.5 0.9 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EAQ89552.1 - 0.12 12.0 1.0 0.14 11.8 0.7 1.3 1 0 0 1 1 1 0 Glycine zipper Cu-oxidase_3 PF07732.10 EAQ89553.1 - 1.2e-40 137.9 8.1 2.5e-39 133.6 0.1 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EAQ89553.1 - 1.2e-32 113.0 0.2 1.3e-30 106.4 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ89553.1 - 2.9e-30 104.5 3.5 2.9e-30 104.5 2.5 2.8 3 0 0 3 3 3 1 Multicopper oxidase TP_methylase PF00590.15 EAQ89554.1 - 6.3e-43 146.9 0.1 1.2e-42 145.9 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EAQ89554.1 - 1e-10 40.7 0.0 3.3e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EAQ89554.1 - 1.1e-05 25.6 0.0 6e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 EAQ89554.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Ras PF00071.17 EAQ89555.1 - 3.4e-54 182.5 0.0 4e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ89555.1 - 7.3e-16 58.7 0.0 1e-15 58.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ89555.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAQ89555.1 - 0.0017 17.5 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAQ89555.1 - 0.0076 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EAQ89555.1 - 0.0086 14.8 0.0 0.009 14.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EAQ89555.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EAQ89555.1 - 0.093 13.0 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CWC25 PF12542.3 EAQ89556.1 - 2e-27 95.4 0.7 2e-27 95.4 0.5 4.1 5 0 0 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.4 EAQ89556.1 - 2.8e-11 43.2 4.0 2.8e-11 43.2 2.8 3.7 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 EAQ89557.1 - 9.7e-19 67.6 0.2 4.6e-18 65.4 0.0 2.2 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EAQ89557.1 - 3e-07 30.3 0.1 6.8e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 EAQ89557.1 - 0.0021 17.9 1.0 2.2 8.3 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ89557.1 - 0.018 14.7 1.2 3.1 7.8 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ89557.1 - 0.29 10.7 2.9 1.6 8.4 0.5 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ89557.1 - 2.2 8.4 6.4 0.78 9.8 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ89557.1 - 9.6 6.2 10.0 0.27 11.1 0.6 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C65 PF10275.4 EAQ89560.1 - 1.7e-66 224.1 0.0 2.1e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain ETX_MTX2 PF03318.8 EAQ89560.1 - 0.011 15.2 0.8 3.6 7.0 0.2 2.6 3 0 0 3 3 3 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 OTU PF02338.14 EAQ89560.1 - 0.065 13.8 0.0 0.25 11.9 0.0 2.0 1 1 0 1 1 1 0 OTU-like cysteine protease BPL_LplA_LipB PF03099.14 EAQ89561.1 - 1.9e-05 24.7 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Rsm22 PF09243.5 EAQ89562.1 - 1.3e-30 106.3 0.0 3.8e-30 104.8 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 EAQ89562.1 - 0.016 14.9 0.0 0.045 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ89562.1 - 0.066 13.6 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF2763 PF10961.3 EAQ89563.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Methyltrn_RNA_3 PF02598.12 EAQ89564.1 - 1.1e-86 290.8 0.0 1.3e-86 290.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EAQ89564.1 - 0.02 14.7 0.0 0.093 12.5 0.0 1.8 2 0 0 2 2 2 0 SpoU rRNA Methylase family Spore_YabQ PF09578.5 EAQ89565.1 - 0.017 15.0 1.0 0.023 14.6 0.7 1.2 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) Atg8 PF02991.11 EAQ89567.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like CPSase_L_D2 PF02786.12 EAQ89568.1 - 4.2e-74 248.3 0.0 6.7e-74 247.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EAQ89568.1 - 2.3e-36 124.0 0.0 4.8e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EAQ89568.1 - 5.5e-35 119.8 0.0 1.3e-34 118.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EAQ89568.1 - 4.1e-19 69.0 0.1 9.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EAQ89568.1 - 9.8e-16 57.1 0.8 2.4e-15 55.8 0.6 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EAQ89568.1 - 1.3e-15 57.0 0.0 2.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EAQ89568.1 - 4.8e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EAQ89568.1 - 8.1e-08 31.7 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EAQ89568.1 - 3.4e-07 29.8 0.0 0.03 13.9 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EAQ89568.1 - 1.7e-05 24.7 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EAQ89568.1 - 3.6e-05 23.2 1.6 0.14 11.4 0.0 3.5 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 EAQ89568.1 - 0.0025 18.1 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein RimK PF08443.6 EAQ89568.1 - 0.019 14.4 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Nairovirus_M PF07948.6 EAQ89568.1 - 0.044 11.9 0.0 0.063 11.3 0.0 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like ATPgrasp_ST PF14397.1 EAQ89568.1 - 0.14 11.2 0.0 0.49 9.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Pyridox_oxidase PF01243.15 EAQ89569.1 - 2.2e-13 50.0 0.0 1.3e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EAQ89569.1 - 0.0032 17.2 0.0 0.31 10.8 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 EAQ89569.1 - 0.062 11.3 0.1 0.073 11.0 0.1 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Mem_trans PF03547.13 EAQ89570.1 - 3.3e-50 170.5 0.1 1.4e-49 168.4 0.0 1.8 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 EAQ89571.1 - 6.5e-34 117.2 0.0 5e-31 107.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89571.1 - 9.7e-21 73.9 0.0 3.3e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EAQ89571.1 - 0.00093 18.1 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EAQ89571.1 - 0.056 13.1 0.2 0.22 11.1 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAQ89571.1 - 0.059 12.1 0.1 0.088 11.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Phostensin_N PF13916.1 EAQ89571.1 - 0.071 13.1 0.8 12 5.9 0.0 2.9 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Kinase-like PF14531.1 EAQ89571.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SUR7 PF06687.7 EAQ89572.1 - 2.5e-37 128.5 5.7 3.2e-37 128.1 4.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EAQ89572.1 - 3e-06 27.0 9.4 3e-06 27.0 6.5 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EAQ89572.1 - 0.077 12.2 5.5 0.13 11.4 3.8 1.4 1 0 0 1 1 1 0 Clc-like Amastin PF07344.6 EAQ89572.1 - 0.23 11.0 10.9 0.51 9.9 7.6 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein ACPS PF01648.15 EAQ89573.1 - 7.7e-07 28.9 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.8 EAQ89574.1 - 1e-46 159.7 9.5 1.2e-45 156.2 6.6 2.2 1 1 0 1 1 1 1 Signal peptide peptidase DUF1700 PF08006.6 EAQ89574.1 - 1.2 8.3 8.6 1.1 8.4 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) TFIIS_C PF01096.13 EAQ89575.1 - 5.9e-21 73.8 2.9 5.9e-21 73.8 2.0 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EAQ89575.1 - 2.5e-08 33.4 0.4 2.5e-08 33.4 0.3 2.6 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EAQ89575.1 - 0.0013 18.5 3.5 0.66 9.8 0.3 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Elf1 PF05129.8 EAQ89575.1 - 0.05 13.3 1.9 2.2 8.0 0.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HC PF01530.13 EAQ89575.1 - 0.12 12.1 1.0 0.12 12.1 0.7 2.4 4 0 0 4 4 4 0 Zinc finger, C2HC type DZR PF12773.2 EAQ89575.1 - 0.36 10.6 4.5 2.1 8.2 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon C1_3 PF07649.7 EAQ89575.1 - 0.57 10.2 0.2 0.57 10.2 0.1 2.7 3 0 0 3 3 3 0 C1-like domain IBR PF01485.16 EAQ89575.1 - 0.99 9.3 8.2 4.9 7.1 2.2 2.9 2 1 0 2 2 2 0 IBR domain Zn_ribbon_recom PF13408.1 EAQ89575.1 - 1 9.6 3.8 2.6 8.3 0.1 2.5 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.1 EAQ89575.1 - 2.7 7.5 5.5 6.5 6.3 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ank_4 PF13637.1 EAQ89576.1 - 1.7e-05 25.1 0.0 0.0019 18.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ89576.1 - 2.5e-05 24.5 0.0 0.00014 22.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ89576.1 - 9.2e-05 22.0 0.8 0.033 13.9 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EAQ89576.1 - 0.00051 20.1 0.1 1.1 9.5 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ89576.1 - 0.0021 18.1 0.0 0.36 11.2 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeat HSP70 PF00012.15 EAQ89577.1 - 1.9e-11 42.5 0.3 8.6e-10 37.1 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EAQ89577.1 - 0.0036 16.9 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EAQ89577.1 - 0.023 13.3 0.1 0.13 10.8 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_1 PF00349.16 EAQ89578.1 - 9.7e-65 217.7 0.1 1.6e-64 217.0 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EAQ89578.1 - 1.4e-61 207.8 0.0 3.2e-61 206.6 0.0 1.6 1 1 0 1 1 1 1 Hexokinase Acetyltransf_1 PF00583.19 EAQ89579.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ89579.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.6 EAQ89580.1 - 0.57 9.5 7.9 0.038 13.2 1.8 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.16 EAQ89581.1 - 2e-49 167.7 0.0 2.5e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CFEM PF05730.6 EAQ89582.1 - 2.9e-10 39.8 12.4 4.9e-10 39.0 8.6 1.4 1 0 0 1 1 1 1 CFEM domain DUF566 PF04484.7 EAQ89582.1 - 2.8 7.3 7.6 3.4 7.0 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Myosin_head PF00063.16 EAQ89584.1 - 1.7e-239 796.5 0.0 1.7e-239 796.5 0.0 2.3 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EAQ89584.1 - 5.7e-31 107.0 152.7 4.1e-24 84.4 53.4 6.6 2 2 2 5 5 5 5 Myosin tail Myosin_N PF02736.14 EAQ89584.1 - 4.7e-06 26.1 0.1 1.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EAQ89584.1 - 0.051 13.3 0.0 0.2 11.4 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain zf-C3H1 PF10650.4 EAQ89585.1 - 3.6e-09 35.9 3.1 5.4e-09 35.3 2.1 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain DivIC PF04977.10 EAQ89585.1 - 0.12 11.9 1.3 0.47 9.9 0.9 2.0 1 0 0 1 1 1 0 Septum formation initiator 4HBT_3 PF13622.1 EAQ89586.1 - 2.5e-38 132.2 2.0 3.6e-38 131.7 1.4 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EAQ89586.1 - 8.5e-20 70.7 0.0 2.4e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 Acyl-CoA thioesterase Oxysterol_BP PF01237.13 EAQ89587.1 - 4.6e-40 137.1 0.3 7.3e-39 133.2 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EAQ89587.1 - 1.3e-18 67.0 0.0 4e-12 46.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ89587.1 - 8.7e-18 63.9 0.5 7.1e-10 38.8 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ89587.1 - 1.2e-17 62.7 0.1 9e-07 28.4 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EAQ89587.1 - 3e-15 56.2 0.0 1.3e-08 35.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ89587.1 - 1.4e-13 49.6 0.2 3.4e-05 23.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 EAQ89587.1 - 3.7e-12 46.3 0.5 7.4e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EAQ89587.1 - 3.2e-08 33.5 1.1 7.7e-08 32.3 0.8 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EAQ89587.1 - 3.2e-08 33.8 1.3 3.2e-08 33.8 0.9 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain EST1_DNA_bind PF10373.4 EAQ89589.1 - 1.1e-16 60.9 0.0 2.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain zinc_ribbon_5 PF13719.1 EAQ89589.1 - 0.2 11.2 0.2 0.54 9.8 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Peptidase_S64 PF08192.6 EAQ89590.1 - 0.015 13.6 0.0 0.021 13.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Gly_transf_sug PF04488.10 EAQ89595.1 - 1.1e-13 51.4 0.0 2.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 EAQ89596.1 - 2.9e-86 289.4 0.0 3.7e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ89596.1 - 8.6e-17 61.8 0.3 2.9e-16 60.1 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_fiss_reg PF05308.6 EAQ89597.1 - 0.14 11.5 4.0 0.15 11.3 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator FAP PF07174.6 EAQ89597.1 - 0.48 9.6 20.4 0.6 9.3 14.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CAP_N PF01213.14 EAQ89597.1 - 2.3 7.3 8.6 2.8 7.1 6.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal adh_short PF00106.20 EAQ89598.1 - 2.3e-35 121.9 1.7 3.1e-35 121.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ89598.1 - 6.3e-19 68.6 0.2 8e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ89598.1 - 7.6e-14 51.7 1.0 1.2e-13 51.1 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ89598.1 - 4.2e-06 26.3 2.0 1.4e-05 24.6 1.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ89598.1 - 9.4e-06 24.5 0.1 1.3e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EAQ89598.1 - 2e-05 24.3 0.3 2.9e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EAQ89598.1 - 0.00021 20.4 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 EAQ89598.1 - 0.0017 17.3 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EAQ89598.1 - 0.0019 17.9 1.3 0.0078 15.9 0.7 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EAQ89598.1 - 0.0033 16.3 0.1 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 EAQ89598.1 - 0.0043 16.6 0.3 0.0061 16.1 0.2 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_10 PF13460.1 EAQ89598.1 - 0.0077 16.2 0.4 0.014 15.4 0.3 1.5 1 0 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 EAQ89598.1 - 0.018 14.8 0.2 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EAQ89598.1 - 0.026 13.4 0.1 0.041 12.8 0.1 1.5 1 1 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 EAQ89598.1 - 0.028 14.8 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Wax2_C PF12076.3 EAQ89598.1 - 0.052 13.2 0.2 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 WAX2 C-terminal domain 2-Hacid_dh_C PF02826.14 EAQ89598.1 - 0.063 12.4 0.1 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EAQ89598.1 - 0.066 12.4 0.2 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family ELFV_dehydrog PF00208.16 EAQ89598.1 - 0.07 12.6 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 EAQ89598.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EAQ89598.1 - 0.12 12.3 0.2 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 EAQ89598.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EAQ89599.1 - 3.3e-33 114.4 0.0 6.3e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 EAQ89599.1 - 0.014 15.6 0.0 0.039 14.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EAQ89599.1 - 0.019 14.9 0.0 0.071 13.1 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EAQ89599.1 - 0.024 13.6 0.1 1.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EAQ89599.1 - 0.029 13.7 0.1 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EAQ89599.1 - 0.043 13.2 0.1 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EAQ89599.1 - 0.091 12.8 0.1 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_17 PF00332.13 EAQ89599.1 - 0.092 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 RTC PF01137.16 EAQ89600.1 - 8.6e-41 139.1 0.0 1.1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase QRPTase_C PF01729.14 EAQ89603.1 - 4.7e-53 179.1 0.1 5.8e-53 178.8 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EAQ89603.1 - 6.2e-22 77.2 0.0 1.6e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.16 EAQ89603.1 - 0.012 14.7 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase VEFS-Box PF09733.4 EAQ89603.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 VEFS-Box of polycomb protein RCC1 PF00415.13 EAQ89604.1 - 5.9e-57 189.6 5.7 1.8e-13 50.4 0.0 8.1 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAQ89604.1 - 1.4e-37 126.4 27.9 1.8e-07 30.5 0.6 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 EAQ89604.1 - 0.027 13.7 0.0 6.2 5.9 0.0 3.3 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF3614 PF12267.3 EAQ89604.1 - 0.38 11.0 4.0 0.6 10.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) Semialdhyde_dh PF01118.19 EAQ89605.1 - 5.1e-29 101.0 0.0 1.5e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EAQ89605.1 - 2e-28 99.5 0.0 3.4e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family DUF619 PF04768.8 EAQ89605.1 - 8.7e-26 90.3 0.0 1.6e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) DapB_N PF01113.15 EAQ89605.1 - 0.024 14.5 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EAQ89606.1 - 5e-16 58.0 0.0 5.7e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Radical_SAM PF04055.16 EAQ89607.1 - 2.8e-16 60.1 0.0 4.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S14 PF00253.16 EAQ89608.1 - 2.4e-17 62.0 0.6 4e-17 61.3 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Ank_4 PF13637.1 EAQ89609.1 - 1.2e-48 162.6 1.9 1.5e-13 50.8 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ89609.1 - 1.3e-47 160.0 0.0 1.4e-26 92.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ89609.1 - 6.1e-46 152.0 0.0 1.6e-08 33.9 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 EAQ89609.1 - 7e-37 121.7 0.0 4.9e-06 26.2 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EAQ89609.1 - 6.6e-36 121.5 0.0 2.5e-10 40.2 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Arb2 PF09757.4 EAQ89610.1 - 1.3e-20 73.6 0.0 2.5e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Arb2 domain NST1 PF13945.1 EAQ89612.1 - 0.056 13.5 2.6 0.086 12.8 1.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4191 PF13829.1 EAQ89612.1 - 0.072 12.1 0.2 0.072 12.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Herpes_LMP1 PF05297.6 EAQ89612.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WD40 PF00400.27 EAQ89614.1 - 4.9e-13 48.4 14.9 0.00019 21.2 0.5 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat DEC-1_N PF04625.8 EAQ89616.1 - 0.35 9.4 5.0 0.41 9.2 3.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Trypan_PARP PF05887.6 EAQ89616.1 - 2.2 8.0 17.6 3.1 7.6 12.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2360 PF10152.4 EAQ89616.1 - 8.2 6.6 7.3 11 6.2 5.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) RRM_1 PF00076.17 EAQ89618.1 - 2e-18 65.8 0.0 3e-12 46.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89618.1 - 1.6e-11 43.9 0.0 2.2e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EAQ89619.1 - 0.12 12.2 4.4 0.22 11.4 3.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Semialdhyde_dhC PF02774.13 EAQ89621.1 - 1.8e-40 138.7 0.0 2.6e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EAQ89621.1 - 2.4e-29 102.0 0.0 8.2e-29 100.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EAQ89621.1 - 0.0031 17.4 0.0 0.0063 16.4 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EAQ89621.1 - 0.01 16.3 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 EAQ89621.1 - 0.091 13.2 0.0 0.34 11.4 0.0 2.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RhoGAP PF00620.22 EAQ89622.1 - 1.9e-26 92.5 0.6 9.4e-14 51.2 0.4 2.3 1 1 1 2 2 2 2 RhoGAP domain TPR_MLP1_2 PF07926.7 EAQ89622.1 - 0.03 14.0 2.9 0.052 13.2 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.6 EAQ89622.1 - 0.23 9.7 2.0 2.3 6.3 1.5 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Siah-Interact_N PF09032.6 EAQ89622.1 - 4.1 7.5 8.5 2.3 8.3 0.1 3.1 3 0 0 3 3 3 0 Siah interacting protein, N terminal DUF1620 PF07774.8 EAQ89623.1 - 1.7e-75 253.0 0.0 1.9e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) LRR_4 PF12799.2 EAQ89624.1 - 2.3e-06 27.0 2.3 4.9e-06 26.0 0.1 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ89624.1 - 8.7e-06 25.4 4.1 2e-05 24.2 0.5 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EAQ89624.1 - 0.018 15.0 4.8 10 6.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat FAR1 PF03101.10 EAQ89627.1 - 3.4e-05 24.2 0.1 4.1e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 FAR1 DNA-binding domain Herpes_LP PF03363.8 EAQ89629.1 - 0.018 14.6 0.3 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus leader protein YrbL-PhoP_reg PF10707.4 EAQ89629.1 - 0.046 13.0 0.2 0.089 12.1 0.0 1.6 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Aldolase_II PF00596.16 EAQ89629.1 - 0.064 12.8 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Ank_2 PF12796.2 EAQ89630.1 - 8.2e-67 221.5 1.9 2.9e-13 49.9 0.0 7.9 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ89630.1 - 1.3e-48 160.4 18.4 0.00011 21.8 0.0 14.8 15 0 0 15 15 15 9 Ankyrin repeat Ank_4 PF13637.1 EAQ89630.1 - 4e-40 135.4 13.7 5.5e-12 45.8 0.0 10.3 8 1 3 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ89630.1 - 1.1e-39 130.5 9.0 0.0011 18.9 0.0 13.5 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 EAQ89630.1 - 2e-32 110.4 18.3 7.9e-08 32.3 0.0 10.4 7 2 4 11 11 11 6 Ankyrin repeats (many copies) ZZ PF00569.12 EAQ89630.1 - 0.0077 15.7 4.1 0.018 14.5 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type tRNA-synt_2 PF00152.15 EAQ89633.1 - 2.7e-59 200.6 0.1 3.8e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAQ89633.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.3 EAQ89633.1 - 0.47 9.1 8.4 0.7 8.5 5.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vma12 PF11712.3 EAQ89634.1 - 0.07 12.8 1.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RNR_inhib PF08591.5 EAQ89635.1 - 8.7e-26 90.7 0.0 8.7e-26 90.7 0.0 2.4 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.12 EAQ89636.1 - 1.2e-08 34.3 0.5 1.6e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 DUF2752 PF10825.3 EAQ89636.1 - 0.09 12.8 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Phosducin PF02114.11 EAQ89637.1 - 1.2e-12 47.1 0.0 1.8e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Phosducin Raptor_N PF14538.1 EAQ89638.1 - 4.9e-64 214.8 0.0 9.2e-64 213.9 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EAQ89638.1 - 8.6e-11 41.2 0.3 1.2 9.1 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EAQ89638.1 - 8.7e-06 25.4 0.1 0.007 16.1 0.1 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 EAQ89638.1 - 0.00051 19.8 0.3 2.7 8.3 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat DUF1900 PF08954.6 EAQ89638.1 - 0.095 12.2 0.0 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1900) Atx10homo_assoc PF09759.4 EAQ89638.1 - 0.22 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Glyco_transf_25 PF01755.12 EAQ89639.1 - 2.6e-06 27.2 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) IncA PF04156.9 EAQ89640.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 IncA protein Sporozoite_P67 PF05642.6 EAQ89640.1 - 0.28 9.0 9.8 0.36 8.6 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sensor PF13796.1 EAQ89640.1 - 1.5 8.4 4.4 0.36 10.3 0.4 1.8 2 0 0 2 2 2 0 Putative sensor Kelch_4 PF13418.1 EAQ89641.1 - 1.9e-30 104.3 12.8 5e-07 29.3 0.8 6.5 4 2 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EAQ89641.1 - 1.1e-29 101.8 7.4 4.5e-09 36.0 0.0 6.5 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EAQ89641.1 - 4e-27 93.4 5.0 3e-10 39.4 0.3 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EAQ89641.1 - 4.9e-26 89.7 10.1 2.1e-12 46.6 0.7 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EAQ89641.1 - 1.4e-25 88.7 11.8 2.7e-07 30.5 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EAQ89641.1 - 4.3e-16 57.9 4.9 8.6e-07 28.4 0.3 6.4 6 0 0 6 6 6 2 Kelch motif Fib_alpha PF08702.5 EAQ89641.1 - 8.1 6.5 39.5 0.48 10.5 0.8 5.0 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family CcmD PF04995.9 EAQ89642.1 - 0.58 9.9 4.5 0.18 11.5 0.8 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) YIF1 PF03878.10 EAQ89643.1 - 2.2e-74 249.6 2.4 2.7e-74 249.3 1.7 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EAQ89643.1 - 9.9e-05 21.9 4.6 9.9e-05 21.9 3.2 1.5 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 EAQ89644.1 - 5.1e-79 265.5 0.0 7.1e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EAQ89644.1 - 8.7e-53 178.6 0.2 1.4e-52 177.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EAQ89644.1 - 6.1e-07 29.4 0.5 2e-06 27.7 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EAQ89644.1 - 1.1e-05 24.3 0.0 2.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EAQ89644.1 - 0.001 18.5 0.2 0.0031 16.9 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EAQ89644.1 - 0.018 14.7 0.5 0.052 13.2 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EAQ89644.1 - 0.02 14.4 0.3 0.041 13.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ89644.1 - 0.028 14.4 0.1 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 EAQ89644.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EAQ89644.1 - 0.051 13.8 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PI3_PI4_kinase PF00454.22 EAQ89645.1 - 1.7e-49 168.4 0.0 3.1e-49 167.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EAQ89645.1 - 4.9e-37 127.7 0.5 8.8e-37 126.8 0.4 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EAQ89645.1 - 1.1e-31 108.8 0.3 6.9e-31 106.3 0.0 2.6 2 0 0 2 2 2 1 UME (NUC010) domain zf-PARP PF00645.13 EAQ89645.1 - 2.3e-21 75.7 0.5 5.1e-21 74.7 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.4 EAQ89647.1 - 1.2e-103 346.8 0.0 1.9e-103 346.3 0.0 1.3 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ICE2 PF08426.5 EAQ89647.1 - 0.052 12.1 0.0 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 ICE2 FAA_hydrolase_N PF09298.6 EAQ89647.1 - 0.16 11.9 1.7 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal PFK PF00365.15 EAQ89648.1 - 1.2e-152 506.7 1.8 3e-119 397.1 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 EAQ89648.1 - 0.0046 16.4 0.2 0.014 14.8 0.1 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Podoplanin PF05808.6 EAQ89649.1 - 0.0096 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Podoplanin PSI_PSAK PF01241.13 EAQ89649.1 - 0.061 13.3 0.3 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK SKG6 PF08693.5 EAQ89649.1 - 0.075 12.3 3.1 0.19 11.1 2.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Protocadherin PF08374.6 EAQ89649.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Protocadherin SNF2_N PF00176.18 EAQ89650.1 - 3.1e-60 203.4 1.4 4.3e-41 140.6 0.1 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ89650.1 - 5.2e-12 45.4 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EAQ89650.1 - 4e-09 35.9 2.1 6.6e-09 35.3 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAQ89650.1 - 4.5e-07 29.7 4.0 8.3e-07 28.9 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ89650.1 - 5.1e-07 29.4 4.3 8.8e-07 28.6 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAQ89650.1 - 2.4e-06 27.1 4.0 4.3e-06 26.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ89650.1 - 3.3e-05 23.4 3.3 6.3e-05 22.6 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EAQ89650.1 - 7e-05 22.6 3.7 0.00016 21.4 2.6 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EAQ89650.1 - 0.0092 15.4 1.5 0.02 14.4 1.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EAQ89650.1 - 0.011 15.4 2.2 0.032 13.9 1.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PTPlike_phytase PF14566.1 EAQ89650.1 - 0.045 13.7 0.6 0.14 12.2 0.4 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-RING_4 PF14570.1 EAQ89650.1 - 0.11 12.1 5.4 0.5 10.0 4.0 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DEAD PF00270.24 EAQ89650.1 - 0.13 11.7 0.3 1.3 8.4 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase DZR PF12773.2 EAQ89650.1 - 2.1 8.2 6.2 1.2 8.9 2.5 2.0 2 0 0 2 2 2 0 Double zinc ribbon Phosphodiest PF01663.17 EAQ89651.1 - 2e-89 300.4 0.3 2.6e-89 300.1 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAQ89651.1 - 0.0022 17.2 0.0 0.059 12.5 0.0 2.2 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 EAQ89651.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 PglZ domain YwiC PF14256.1 EAQ89651.1 - 0.071 13.1 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 YwiC-like protein Acetyltransf_7 PF13508.1 EAQ89652.1 - 0.00012 22.2 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ89652.1 - 0.00064 19.7 0.1 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAQ89652.1 - 0.022 14.8 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_5 PF12695.2 EAQ89652.1 - 0.049 13.3 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_9 PF13527.1 EAQ89652.1 - 0.06 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAQ89652.1 - 0.087 12.7 0.0 0.38 10.6 0.0 2.0 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_L14e PF01929.12 EAQ89653.1 - 9.4e-29 99.5 1.8 1.4e-28 99.0 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 NAC PF01849.13 EAQ89654.1 - 2e-25 88.0 0.1 2.9e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 NAC domain Myc_N PF01056.13 EAQ89654.1 - 0.0056 15.8 1.5 0.0056 15.8 1.1 1.7 2 0 0 2 2 2 1 Myc amino-terminal region EBV-NA3 PF05009.7 EAQ89654.1 - 1.3 8.1 10.8 1.1 8.4 0.9 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF2946 PF11162.3 EAQ89654.1 - 1.4 9.1 5.1 2.9 8.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) PP1c_bdg PF10488.4 EAQ89654.1 - 2.1 7.4 7.0 0.34 10.0 0.8 2.0 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region Mt_ATP-synt_D PF05873.7 EAQ89655.1 - 1.2e-18 67.2 2.0 1.5e-18 66.9 1.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TRADD_N PF09034.5 EAQ89655.1 - 0.029 14.3 0.2 0.045 13.7 0.2 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Dor1 PF04124.7 EAQ89655.1 - 0.039 12.4 2.0 0.047 12.1 1.4 1.1 1 0 0 1 1 1 0 Dor1-like family T5orf172 PF10544.4 EAQ89655.1 - 0.065 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 T5orf172 domain IncA PF04156.9 EAQ89655.1 - 1.1 8.7 4.0 1.7 8.1 2.4 1.4 1 1 0 1 1 1 0 IncA protein COX16 PF14138.1 EAQ89657.1 - 8.9e-31 105.8 0.0 1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Amidohydro_1 PF01979.15 EAQ89660.1 - 1.9e-06 27.7 0.6 3.3e-05 23.6 0.4 2.4 1 1 0 1 1 1 1 Amidohydrolase family DUF1687 PF07955.6 EAQ89662.1 - 4.8e-18 65.4 0.0 1.7e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EAQ89662.1 - 0.048 13.7 0.0 0.83 9.7 0.0 2.2 1 1 0 1 1 1 0 ArsC family GP40 PF11025.3 EAQ89662.1 - 0.071 12.6 0.1 0.08 12.5 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium Sel1 PF08238.7 EAQ89665.1 - 6.1e-42 141.1 22.8 3.1e-06 27.6 0.0 8.0 7 0 0 7 7 7 7 Sel1 repeat CBP4 PF07960.6 EAQ89666.1 - 2.6e-34 117.5 1.3 2.8e-34 117.4 0.9 1.0 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.3 EAQ89666.1 - 0.0055 16.6 0.5 0.012 15.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) DUF1491 PF07372.7 EAQ89666.1 - 0.044 13.7 1.6 0.092 12.6 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) ERCC4 PF02732.10 EAQ89666.1 - 0.061 13.0 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 ERCC4 domain UPF0258 PF06789.7 EAQ89666.1 - 0.079 13.0 0.3 0.095 12.7 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DASH_Spc19 PF08287.6 EAQ89666.1 - 0.14 11.7 2.8 0.19 11.3 1.9 1.1 1 0 0 1 1 1 0 Spc19 Seryl_tRNA_N PF02403.17 EAQ89666.1 - 1 9.4 7.0 1.9 8.5 4.8 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NAC PF01849.13 EAQ89667.1 - 1.5e-21 75.6 0.3 4.3e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.13 EAQ89668.1 - 2.1e-56 191.7 0.0 2.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Mito_fiss_reg PF05308.6 EAQ89668.1 - 7 5.9 9.6 11 5.3 6.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L24e PF01246.15 EAQ89669.1 - 5.8e-31 106.1 0.3 5.8e-31 106.1 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.5 EAQ89670.1 - 4.7e-38 129.9 0.0 5.3e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EAQ89670.1 - 1.2e-09 37.8 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF295 PF03478.13 EAQ89670.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF295) DUF1348 PF07080.6 EAQ89671.1 - 3.7e-18 65.6 0.2 4.9e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) Pkinase PF00069.20 EAQ89672.1 - 3.5e-06 26.3 0.0 4.2e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89672.1 - 0.0066 15.5 0.0 0.0073 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EAQ89673.1 - 0.00051 20.1 0.0 0.061 13.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Claudin_2 PF13903.1 EAQ89673.1 - 0.11 12.2 3.2 0.35 10.5 1.4 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fumble PF03630.9 EAQ89674.1 - 1.4e-128 428.6 0.0 1.2e-127 425.4 0.0 2.1 1 1 0 1 1 1 1 Fumble MPC PF03650.8 EAQ89675.1 - 4.6e-42 142.7 0.7 6.4e-42 142.2 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Abhydrolase_6 PF12697.2 EAQ89677.1 - 2e-10 40.9 0.6 3.3e-10 40.2 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ89677.1 - 0.00014 21.4 0.0 0.00026 20.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ89677.1 - 0.00037 20.2 0.1 0.001 18.8 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EAQ89677.1 - 0.13 12.0 0.0 6.1 6.4 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EAQ89677.1 - 0.81 9.8 3.1 0.79 9.9 1.0 1.8 2 0 0 2 2 2 0 Thioesterase domain RNase_PH PF01138.16 EAQ89678.1 - 7.5e-09 35.9 0.0 9.4e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAQ89678.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 GDI PF00996.13 EAQ89679.1 - 2.2e-36 125.1 0.0 2.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8 PF04824.11 EAQ89680.1 - 1.1e-08 34.1 0.0 3.2e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N PF04825.8 EAQ89680.1 - 0.0067 16.3 0.2 0.062 13.2 0.1 2.1 1 1 1 2 2 2 2 N terminus of Rad21 / Rec8 like protein Apolipo_F PF15148.1 EAQ89680.1 - 0.039 13.2 0.4 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Apolipoprotein F ALO PF04030.9 EAQ89681.1 - 2.1e-96 322.4 0.6 2.6e-96 322.1 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EAQ89681.1 - 4.7e-28 97.3 0.2 6.9e-28 96.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BTB PF00651.26 EAQ89682.1 - 8.3e-28 96.6 0.0 1.3e-13 50.9 0.1 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EAQ89682.1 - 2.4e-10 40.6 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ89682.1 - 3.1e-10 39.3 2.3 0.0001 21.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EAQ89682.1 - 7e-09 35.9 0.1 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ89682.1 - 5.7e-08 32.7 0.2 3.1e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ89682.1 - 1.2e-06 28.2 0.1 0.0049 16.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat FAR1 PF03101.10 EAQ89683.1 - 0.19 12.2 1.9 0.33 11.5 1.3 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain DOR PF14839.1 EAQ89683.1 - 2.8 7.6 7.5 3.6 7.2 5.2 1.3 1 0 0 1 1 1 0 DOR family Pkinase PF00069.20 EAQ89684.1 - 2.1e-58 197.5 0.0 3.3e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89684.1 - 1.6e-36 125.7 0.0 3.2e-26 91.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89684.1 - 0.0073 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF607 PF04678.8 EAQ89684.1 - 0.061 13.2 0.3 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 XhlA PF10779.4 EAQ89684.1 - 0.21 11.5 4.4 0.66 9.9 3.1 1.8 1 0 0 1 1 1 0 Haemolysin XhlA APG6 PF04111.7 EAQ89684.1 - 0.41 9.6 8.5 0.72 8.8 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 EAQ89684.1 - 1.2 7.2 14.7 0.2 9.9 6.2 1.9 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2 PF00096.21 EAQ89687.1 - 1.2e-09 37.8 10.5 0.00015 21.9 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ89687.1 - 1e-07 31.8 9.8 9.2e-07 28.8 0.6 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ89687.1 - 8.9e-06 25.6 8.5 0.0068 16.6 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Dicty_CAD PF05720.7 EAQ89687.1 - 0.047 13.3 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Cell-cell adhesion domain zf-C2H2_jaz PF12171.3 EAQ89687.1 - 0.071 13.2 4.1 0.27 11.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ89687.1 - 0.092 12.9 2.1 0.35 11.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Lipase_GDSL_2 PF13472.1 EAQ89688.1 - 9.3e-10 38.9 0.4 4.2e-09 36.7 0.3 2.0 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ89688.1 - 6.2e-09 36.0 3.3 7.6e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EAQ89688.1 - 0.014 15.0 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SMP_2 PF10144.4 EAQ89689.1 - 0.0051 15.9 0.1 0.0066 15.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin DUF2365 PF10157.4 EAQ89689.1 - 0.0062 16.4 0.1 0.0099 15.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) Rnk_N PF14760.1 EAQ89689.1 - 0.14 12.2 4.5 0.3 11.1 1.4 2.5 2 0 0 2 2 2 0 Rnk N-terminus PHD PF00628.24 EAQ89690.1 - 1.1e-12 47.4 7.8 1.1e-12 47.4 5.4 2.1 3 0 0 3 3 3 1 PHD-finger zf-H2C2_2 PF13465.1 EAQ89690.1 - 0.14 12.5 1.2 0.4 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_2 PF13639.1 EAQ89690.1 - 0.57 10.0 6.1 1.3 8.8 4.2 1.7 1 0 0 1 1 1 0 Ring finger domain SCO1-SenC PF02630.9 EAQ89691.1 - 3e-51 173.4 0.0 4.3e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EAQ89691.1 - 0.00014 21.8 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Choline_kinase PF01633.15 EAQ89692.1 - 8.8e-30 103.8 0.0 5e-29 101.3 0.0 2.2 2 1 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EAQ89692.1 - 1.8e-22 78.5 0.0 3.3e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus DUF3433 PF11915.3 EAQ89694.1 - 2.1e-17 63.0 1.3 2.1e-17 63.0 0.9 3.2 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Transgly_assoc PF04226.8 EAQ89694.1 - 0.036 14.1 1.1 0.19 11.8 0.7 2.3 1 1 0 1 1 1 0 Transglycosylase associated protein Phage_integ_N PF09003.5 EAQ89694.1 - 0.11 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda integrase, N-terminal domain DUF3565 PF12088.3 EAQ89696.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) Hydrolase_6 PF13344.1 EAQ89698.1 - 1.6e-26 92.1 0.0 2.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ89698.1 - 0.0011 19.4 0.0 0.44 10.9 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ89698.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ89698.1 - 0.024 14.3 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like OPT PF03169.10 EAQ89699.1 - 9.7e-183 608.9 56.7 1.2e-182 608.7 39.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EAQ89699.1 - 0.85 8.6 1.9 1.7 7.6 0.1 2.1 2 0 0 2 2 2 0 E1-E2 ATPase MoaE PF02391.12 EAQ89700.1 - 3.8e-16 58.9 0.0 5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.18 EAQ89701.1 - 9.2e-11 41.3 1.7 1.9e-10 40.3 1.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EAQ89701.1 - 2.3e-07 30.3 0.5 0.001 18.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89701.1 - 4e-06 26.6 0.1 0.048 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EAQ89701.1 - 2.3e-05 23.4 0.1 4.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EAQ89701.1 - 0.001 18.8 4.3 0.002 17.9 1.8 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EAQ89701.1 - 0.0044 16.8 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 EAQ89701.1 - 0.1 11.7 0.2 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region Ribosomal_60s PF00428.14 EAQ89701.1 - 0.24 11.8 0.1 0.24 11.8 0.0 4.4 4 1 0 4 4 4 0 60s Acidic ribosomal protein DUF1895 PF08988.5 EAQ89702.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Asp PF00026.18 EAQ89703.1 - 6.5e-49 166.8 0.5 5e-39 134.4 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ89703.1 - 1e-07 32.0 0.0 1e-07 32.0 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ89703.1 - 0.0014 19.0 0.6 1.6 9.3 0.1 2.7 2 0 0 2 2 2 2 Aspartyl protease HATPase_c PF02518.21 EAQ89704.1 - 3.2e-24 84.7 0.0 6.6e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EAQ89704.1 - 8.5e-23 80.7 0.0 1.6e-07 31.6 0.0 3.9 4 0 0 4 4 4 3 PAS domain PAS_8 PF13188.1 EAQ89704.1 - 3.9e-10 39.2 0.0 0.00067 19.4 0.0 4.5 4 0 0 4 4 4 2 PAS domain Response_reg PF00072.19 EAQ89704.1 - 1.2e-09 38.1 0.2 4.6e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 EAQ89704.1 - 1.5e-09 37.8 0.0 0.0018 18.2 0.0 5.4 5 0 0 5 5 5 1 PAS fold PAS PF00989.19 EAQ89704.1 - 4.2e-09 36.1 0.0 0.0016 18.2 0.0 3.1 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 EAQ89704.1 - 1.6e-08 34.4 0.9 4.6e-07 29.7 0.1 3.5 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EAQ89704.1 - 1.1e-07 31.7 0.1 0.017 15.1 0.0 3.3 3 1 0 3 3 3 2 PAS fold GAF_3 PF13492.1 EAQ89704.1 - 0.0021 18.1 0.0 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 GAF domain Polyketide_cyc2 PF10604.4 EAQ89705.1 - 9.4e-06 25.8 3.1 0.00044 20.4 2.1 2.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TP2 PF01254.13 EAQ89706.1 - 7.8 6.8 12.7 18 5.6 1.5 2.2 1 1 1 2 2 2 0 Nuclear transition protein 2 HlyIII PF03006.15 EAQ89707.1 - 4 6.7 7.7 0.12 11.7 0.6 2.0 3 0 0 3 3 3 0 Haemolysin-III related Pex14_N PF04695.8 EAQ89708.1 - 3.8 7.5 24.7 0.084 12.9 5.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_2 PF00891.13 EAQ89709.1 - 3.5e-34 118.0 0.0 5.4e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAQ89709.1 - 2.9e-05 24.5 0.0 8.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ89709.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.13 EAQ89709.1 - 0.077 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.1 EAQ89710.1 - 2.5e-08 33.8 0.0 1.2e-06 28.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ89710.1 - 8.3e-05 23.1 0.1 0.0004 20.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EAQ89710.1 - 0.0065 15.6 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EAQ89710.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EAQ89710.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 EAQ89710.1 - 0.16 12.4 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCI PF01399.22 EAQ89711.1 - 1.3e-20 73.6 0.0 4.2e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain EST1_DNA_bind PF10373.4 EAQ89711.1 - 0.19 10.9 2.1 3.5 6.7 0.0 2.7 2 1 1 3 3 3 0 Est1 DNA/RNA binding domain DUF3441 PF11923.3 EAQ89712.1 - 3.1e-36 123.4 0.4 1e-35 121.7 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EAQ89712.1 - 2.2e-31 108.9 11.6 2.2e-31 108.9 8.1 2.3 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EAQ89712.1 - 4.6e-25 87.3 0.0 9.4e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) eIF-5a PF01287.15 EAQ89713.1 - 1.4e-07 31.3 0.1 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF89 PF01937.14 EAQ89713.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 S1-P1_nuclease PF02265.11 EAQ89719.1 - 1.5e-72 244.2 0.0 2e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.9 EAQ89720.1 - 1.2e-20 72.8 1.7 3.1e-16 58.6 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat F-box-like PF12937.2 EAQ89721.1 - 3.3e-05 23.5 0.0 8.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAQ89721.1 - 0.94 9.1 5.4 23 4.7 0.1 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) UPF0139 PF03669.8 EAQ89722.1 - 5.9e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) HTH_38 PF13936.1 EAQ89722.1 - 0.0033 16.9 0.4 0.0081 15.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EAQ89722.1 - 0.0051 16.4 0.5 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain Med12 PF09497.5 EAQ89723.1 - 7.9e-29 99.4 0.3 1.5e-28 98.5 0.2 1.5 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EAQ89723.1 - 0.0024 16.4 0.0 0.077 11.4 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain TAN PF11640.3 EAQ89723.1 - 0.096 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair HET PF06985.6 EAQ89724.1 - 4.5e-23 81.9 0.0 1.2e-22 80.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Trypan_PARP PF05887.6 EAQ89724.1 - 0.37 10.5 20.3 3.5 7.4 11.7 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 EAQ89724.1 - 3 6.1 20.6 5.4 5.2 14.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PRCC PF10253.4 EAQ89724.1 - 8.9 6.9 6.1 18 5.9 4.2 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FAD_binding_4 PF01565.18 EAQ89725.1 - 1.6e-12 47.1 2.2 2.5e-12 46.4 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain APH PF01636.18 EAQ89726.1 - 1.1e-12 48.1 0.0 2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EAQ89726.1 - 0.00063 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EAQ89726.1 - 0.0025 16.5 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EAQ89726.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Alpha_kinase PF02816.13 EAQ89727.1 - 1e-41 142.6 0.0 1.2e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family BTB PF00651.26 EAQ89728.1 - 3.6e-12 46.2 0.0 9.6e-12 44.8 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain Nucleoporin_FG PF13634.1 EAQ89728.1 - 0.012 15.8 9.2 0.03 14.5 6.4 1.6 1 0 0 1 1 1 0 Nucleoporin FG repeat region WSC PF01822.14 EAQ89729.1 - 1.8e-26 91.8 8.6 3.4e-21 74.9 1.5 3.9 3 1 1 4 4 4 3 WSC domain RabGAP-TBC PF00566.13 EAQ89730.1 - 4.1e-45 153.8 0.0 6.2e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EAQ89730.1 - 6.8e-05 22.4 0.5 0.0092 15.7 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EAQ89730.1 - 0.0019 18.3 0.0 0.088 12.9 0.1 2.6 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EAQ89730.1 - 0.011 15.0 0.1 0.49 9.8 0.1 3.2 2 0 0 2 2 2 0 EF hand DUF416 PF04222.7 EAQ89730.1 - 0.18 10.9 0.1 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Sigma70_ner PF04546.8 EAQ89730.1 - 5.7 6.5 12.9 8 6.0 2.9 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 EAQ89730.1 - 7.1 6.8 14.0 12 6.1 2.7 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Pkinase PF00069.20 EAQ89731.1 - 8.3e-45 152.9 0.0 1.1e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89731.1 - 5.2e-19 68.3 0.0 7e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ89731.1 - 0.00059 19.6 0.5 0.12 12.0 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAQ89731.1 - 0.046 12.5 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EAQ89731.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Exo_endo_phos PF03372.18 EAQ89732.1 - 4.1e-08 33.4 7.8 1.3e-07 31.7 5.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EAQ89733.1 - 3.2e-17 62.5 0.0 3.3e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pal1 PF08316.6 EAQ89735.1 - 4.4e-47 160.0 0.3 4.4e-47 160.0 0.2 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein Fasciclin PF02469.17 EAQ89736.1 - 2.5e-06 27.5 0.1 4e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Fasciclin domain LysM PF01476.15 EAQ89738.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 LysM domain PIF1 PF05970.9 EAQ89739.1 - 2.6e-11 43.0 0.0 9.4e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ89739.1 - 0.003 17.6 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ89739.1 - 0.012 13.4 0.0 0.016 12.9 0.0 1.1 1 0 0 1 1 1 0 Helicase Glyco_hydro_18 PF00704.23 EAQ89741.1 - 1.3e-28 100.4 1.7 2.4e-28 99.5 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EAQ89741.1 - 7.7e-06 25.6 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EAQ89741.1 - 0.00031 20.6 3.0 0.00031 20.6 2.1 3.0 4 0 0 4 4 4 1 Chitin recognition protein DUF3142 PF11340.3 EAQ89741.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DNase_NucA_NucB PF14040.1 EAQ89742.1 - 0.005 16.9 0.2 0.025 14.7 0.1 2.2 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB zf-C2H2_4 PF13894.1 EAQ89743.1 - 0.002 18.2 16.6 0.012 15.8 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger Adeno_E3_CR2 PF02439.10 EAQ89743.1 - 0.021 14.3 0.3 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-C2H2 PF00096.21 EAQ89743.1 - 0.032 14.5 0.9 0.032 14.5 0.6 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type HSP70 PF00012.15 EAQ89745.1 - 1.4e-78 264.2 1.7 1.4e-78 264.2 1.2 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ89745.1 - 2.1e-07 29.8 0.3 3.9e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PBP1_TM PF14812.1 EAQ89745.1 - 1 9.7 5.9 2.2 8.6 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2890 PF11081.3 EAQ89745.1 - 2.5 8.1 10.5 1.2 9.1 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) zf-C3HC4_2 PF13923.1 EAQ89746.1 - 0.00093 19.1 3.5 0.00093 19.1 2.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ89746.1 - 0.00095 18.9 1.1 0.00095 18.9 0.8 2.2 2 0 0 2 2 2 1 Ring finger domain Nop14 PF04147.7 EAQ89746.1 - 0.54 8.1 10.3 0.71 7.7 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EAQ89746.1 - 1.6 8.2 12.0 2.8 7.4 8.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin zf-C3HC4_2 PF13923.1 EAQ89747.1 - 1.9e-05 24.5 0.4 1.9e-05 24.5 0.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ89747.1 - 0.0011 18.5 0.1 0.0011 18.5 0.1 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ89747.1 - 0.015 15.1 0.1 0.015 15.1 0.1 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAQ89747.1 - 0.041 13.6 1.7 0.057 13.1 0.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EAQ89747.1 - 0.082 12.4 2.8 0.45 10.0 0.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 EAQ89747.1 - 0.19 11.4 9.3 0.074 12.7 1.9 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAQ89747.1 - 0.25 11.0 8.9 0.038 13.6 1.4 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ89747.1 - 0.33 10.8 10.5 0.53 10.1 3.3 3.0 2 1 0 2 2 2 0 Ring finger domain SelP_N PF04592.9 EAQ89747.1 - 0.76 9.1 5.3 1.2 8.4 3.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-RING_4 PF14570.1 EAQ89747.1 - 7.5 6.2 7.9 2.2 7.9 1.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain POP1 PF06978.6 EAQ89749.1 - 1e-65 220.9 14.0 1.8e-65 220.1 9.7 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EAQ89749.1 - 1.4e-31 108.1 0.1 4e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain IBR PF01485.16 EAQ89750.1 - 9.3e-12 44.6 29.8 2.2e-06 27.4 3.6 3.5 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EAQ89750.1 - 0.00062 19.5 1.7 0.00062 19.5 1.2 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ89750.1 - 0.0021 18.0 1.6 0.0021 18.0 1.1 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAQ89750.1 - 0.0034 17.0 0.1 0.0034 17.0 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EAQ89750.1 - 0.011 15.3 1.6 0.011 15.3 1.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ89750.1 - 0.026 14.2 0.8 0.026 14.2 0.6 3.7 3 1 0 3 3 3 0 zinc-RING finger domain MSA-2c PF12238.3 EAQ89750.1 - 8.8 5.9 10.3 20 4.7 7.2 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c SH3_1 PF00018.23 EAQ89751.1 - 1.8e-14 52.8 0.0 2.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAQ89751.1 - 1.9e-10 40.1 0.0 3.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAQ89751.1 - 1.8e-08 33.7 0.0 2.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.8 EAQ89751.1 - 0.39 10.7 9.7 0.6 10.1 1.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRCC PF10253.4 EAQ89751.1 - 3 8.4 8.3 0.62 10.7 1.1 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CNH PF00780.17 EAQ89752.1 - 7.8e-81 271.5 0.0 3e-80 269.5 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EAQ89752.1 - 4e-42 143.3 0.0 1.1e-41 141.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EAQ89752.1 - 9.7e-35 120.0 0.0 1.8e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EAQ89752.1 - 7.7e-15 54.3 0.1 1.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 EAQ89753.1 - 1.5e-25 88.8 29.0 4e-15 55.4 5.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SR-25 PF10500.4 EAQ89754.1 - 1.2 8.5 11.1 0.28 10.6 0.1 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Metallophos PF00149.23 EAQ89756.1 - 1.8e-05 24.1 1.0 3e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1148 PF06618.6 EAQ89757.1 - 0.067 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) zf-C2H2 PF00096.21 EAQ89758.1 - 0.00022 21.3 1.6 0.00022 21.3 1.1 4.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ89758.1 - 0.0097 16.1 1.1 0.0097 16.1 0.8 5.0 5 0 0 5 5 5 2 C2H2-type zinc finger Zn_clus PF00172.13 EAQ89758.1 - 0.01 15.7 5.6 0.033 14.0 3.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDOST_48kD PF03345.9 EAQ89760.1 - 2.7e-144 480.8 0.0 1.2e-143 478.6 0.0 1.9 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.13 EAQ89760.1 - 3.9e-106 354.4 0.0 6.5e-106 353.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 EAQ89760.1 - 1.6e-11 44.6 0.0 4.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 EAQ89760.1 - 3.8e-11 42.7 0.0 1.1e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EAQ89760.1 - 1.1e-05 25.0 0.6 0.13 12.1 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EAQ89761.1 - 1.5e-53 181.7 11.1 2.3e-53 181.1 7.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAQ89761.1 - 4.9e-22 78.3 0.5 1.3e-21 76.9 0.4 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 TryThrA_C PF12319.3 EAQ89762.1 - 0.04 13.0 0.5 0.091 11.9 0.1 1.7 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal FAD_binding_4 PF01565.18 EAQ89763.1 - 4.5e-19 68.2 2.6 2.1e-18 66.1 0.4 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAQ89763.1 - 2.3e-12 46.6 0.0 5.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NACHT PF05729.7 EAQ89764.1 - 1.9e-08 34.1 0.0 3.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.1 EAQ89764.1 - 0.0063 15.6 0.2 5 6.1 0.0 3.3 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EAQ89764.1 - 0.037 13.7 10.4 2.5 7.8 0.0 5.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat TruB_C PF09142.6 EAQ89764.1 - 0.067 12.8 4.9 0.92 9.1 0.0 4.5 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal PQQ_2 PF13360.1 EAQ89764.1 - 0.19 11.1 5.4 5.1 6.4 0.1 4.0 3 1 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 EAQ89764.1 - 0.26 11.2 12.2 9.4 6.3 0.0 6.6 8 0 0 8 8 8 0 WD domain, G-beta repeat Nup160 PF11715.3 EAQ89764.1 - 6.1 4.8 6.5 1.8 6.5 0.0 3.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 2OG-FeII_Oxy_2 PF13532.1 EAQ89767.1 - 6.6e-20 71.7 0.5 1.6e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Utp14 PF04615.8 EAQ89767.1 - 0.43 8.6 9.6 0.63 8.1 6.7 1.1 1 0 0 1 1 1 0 Utp14 protein AMP-binding PF00501.23 EAQ89768.1 - 1.8e-32 112.2 0.4 6e-18 64.4 0.0 3.3 2 1 1 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ89768.1 - 6.5e-17 62.2 0.2 7.7e-16 58.8 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 EAQ89769.1 - 1e-31 109.7 0.0 1.4e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EAQ89769.1 - 0.0057 15.4 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Pirin PF02678.11 EAQ89770.1 - 8.9e-22 76.9 0.8 3.5e-20 71.8 0.5 2.3 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EAQ89770.1 - 6.8e-07 28.6 2.9 0.00016 21.1 0.2 3.3 2 1 0 2 2 2 2 Cupin domain Parvo_coat PF00740.13 EAQ89770.1 - 0.073 12.0 0.1 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Glu-tRNAGln PF02686.10 EAQ89771.1 - 0.13 12.1 0.5 4.7 7.0 0.0 2.5 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Ank_5 PF13857.1 EAQ89772.1 - 1.3e-05 25.2 0.6 2.9e-05 24.1 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_3 PF13878.1 EAQ89772.1 - 0.046 13.2 1.8 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CFEM PF05730.6 EAQ89773.1 - 4.4e-05 23.2 2.4 4.4e-05 23.2 1.7 2.6 2 0 0 2 2 2 1 CFEM domain TFIIA PF03153.8 EAQ89773.1 - 5.1 6.8 12.4 9 6.0 8.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit T5orf172 PF10544.4 EAQ89774.1 - 5.4e-16 58.8 0.0 9.1e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EAQ89774.1 - 8.5e-15 54.9 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Zn_clus PF00172.13 EAQ89776.1 - 1.4e-08 34.5 11.9 2.2e-08 33.8 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Annexin PF00191.15 EAQ89777.1 - 2.7e-18 65.6 3.5 9.9e-05 22.1 0.0 4.7 4 1 0 4 4 4 4 Annexin CDC45 PF02724.9 EAQ89777.1 - 3.7 5.4 8.2 5.7 4.8 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein GPI2 PF06432.6 EAQ89779.1 - 1.2e-125 418.5 0.1 1.4e-125 418.3 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1049 PF06305.6 EAQ89779.1 - 0.13 11.7 1.2 2.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SSP160 PF06933.6 EAQ89779.1 - 1.7 6.5 17.2 0.11 10.4 4.5 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EAQ89779.1 - 3.6 7.3 11.0 0.86 9.3 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CNH PF00780.17 EAQ89780.1 - 5.5e-69 232.6 0.0 8.2e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EAQ89780.1 - 1.3e-30 106.5 0.0 2.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EAQ89780.1 - 7.5e-11 42.1 0.3 1.6e-09 37.7 0.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EAQ89780.1 - 3.4e-05 24.0 0.0 0.00011 22.3 0.0 1.9 1 1 0 1 1 1 1 PH domain Sod_Cu PF00080.15 EAQ89781.1 - 6.2e-44 149.5 7.1 7.3e-44 149.3 4.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 EAQ89782.1 - 2e-71 237.1 0.1 1.7e-22 79.7 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EAQ89782.1 - 9.3e-24 83.6 0.0 3.2e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EAQ89782.1 - 1.3e-06 27.7 0.0 2.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Transaldolase PF00923.14 EAQ89783.1 - 5.4e-92 307.9 1.5 6.7e-92 307.6 1.0 1.0 1 0 0 1 1 1 1 Transaldolase Metallophos_2 PF12850.2 EAQ89784.1 - 5e-08 32.9 0.0 6.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ89784.1 - 2.5e-06 27.0 0.2 8.3e-06 25.3 0.0 1.9 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase DUF3973 PF13119.1 EAQ89786.1 - 9.1 6.3 5.8 25 4.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3973) Pet191_N PF10203.4 EAQ89787.1 - 7.2e-28 96.4 4.6 9.6e-28 96.0 3.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EAQ89787.1 - 0.22 11.2 4.3 5.7 6.7 0.3 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydro_lipase PF04083.11 EAQ89788.1 - 6.4e-22 76.6 0.0 1.2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EAQ89788.1 - 2.5e-17 63.2 0.1 1.1e-16 61.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ89788.1 - 3.8e-07 30.2 0.1 9.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EAQ89788.1 - 0.0007 19.0 0.0 0.52 9.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EAQ89788.1 - 0.12 11.7 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF605 PF04652.11 EAQ89788.1 - 2.1 7.6 12.6 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Vta1 like MMR_HSR1 PF01926.18 EAQ89789.1 - 3.4e-11 43.1 0.0 1.1e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAQ89789.1 - 0.00081 19.2 0.2 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EAQ89789.1 - 0.0044 16.2 0.2 0.035 13.3 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAQ89789.1 - 0.016 14.5 0.1 0.059 12.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.16 EAQ89789.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.1 EAQ89789.1 - 0.039 13.9 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EAQ89789.1 - 0.051 14.3 0.1 0.25 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ89789.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EAQ89789.1 - 0.14 12.4 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain PHD PF00628.24 EAQ89790.1 - 5.1e-10 38.8 2.0 5.1e-10 38.8 1.4 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EAQ89790.1 - 0.02 14.1 3.5 0.038 13.2 2.4 1.4 1 0 0 1 1 1 0 PHD-finger RNA_pol_3_Rpc31 PF11705.3 EAQ89791.1 - 0.0019 18.1 2.7 0.004 17.1 1.9 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Catalase-rel PF06628.7 EAQ89792.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive UvrD_C_2 PF13538.1 EAQ89793.1 - 0.00043 20.3 0.0 0.0028 17.7 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ89793.1 - 0.00071 17.4 0.0 0.001 16.9 0.0 1.1 1 0 0 1 1 1 1 Helicase zf-DNL PF05180.7 EAQ89793.1 - 0.084 12.5 1.0 0.16 11.6 0.7 1.4 1 0 0 1 1 1 0 DNL zinc finger adh_short_C2 PF13561.1 EAQ89796.1 - 1.6e-18 67.3 0.0 2.3e-12 47.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ89796.1 - 8.3e-15 55.0 0.4 5.2e-13 49.2 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAQ89796.1 - 2.4e-08 33.8 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Carboxyl_trans PF01039.17 EAQ89797.1 - 1.1e-137 459.4 0.3 1.3e-137 459.1 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EAQ89797.1 - 0.0021 17.2 0.5 0.16 11.1 0.0 2.6 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 EAQ89798.1 - 4.4e-43 146.9 3.2 8.6e-43 146.0 2.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAQ89798.1 - 1.4e-30 106.1 0.1 3.1e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ89798.1 - 7.5e-20 70.1 0.1 1.7e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EAQ89798.1 - 6.5e-15 55.5 1.4 6.5e-15 55.5 1.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EAQ89798.1 - 0.001 18.5 0.3 0.004 16.5 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.23 EAQ89800.1 - 8.5e-11 41.6 0.1 4.5e-10 39.2 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.13 EAQ89801.1 - 1.2e-07 31.2 0.0 2.1e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family WD40 PF00400.27 EAQ89802.1 - 1.7e-08 34.0 7.7 4.3e-07 29.5 0.2 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EAQ89802.1 - 1.2 9.0 8.8 2.8 7.8 6.1 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.21 EAQ89803.1 - 2.2e-17 62.8 0.0 5.3e-10 38.8 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme ADH_zinc_N PF00107.21 EAQ89804.1 - 7.3e-11 41.7 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ89804.1 - 0.0043 17.9 0.0 0.0079 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_L12 PF00542.14 EAQ89804.1 - 0.053 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain PI3Ka PF00613.15 EAQ89805.1 - 1.3e-57 194.0 0.8 2.2e-57 193.2 0.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EAQ89805.1 - 4.6e-44 150.6 0.1 1.8e-42 145.4 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EAQ89805.1 - 8.7e-26 90.4 0.1 1.7e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 EAQ89805.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Nse4_C PF08743.5 EAQ89806.1 - 3.4e-35 119.9 0.0 1.2e-34 118.1 0.0 2.1 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EAQ89806.1 - 4.5e-17 61.6 0.1 2.8e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1598 PF07643.6 EAQ89806.1 - 0.16 12.0 4.3 0.096 12.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) VP4_haemagglut PF00426.13 EAQ89806.1 - 0.89 7.4 3.4 8.6 4.1 0.4 2.2 2 0 0 2 2 2 0 Outer Capsid protein VP4 (Hemagglutinin) DUF1062 PF06353.7 EAQ89807.1 - 0.024 14.8 0.3 0.048 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Lipase_3 PF01764.20 EAQ89808.1 - 7.1e-12 45.1 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Alpha-amyl_C2 PF07821.7 EAQ89808.1 - 0.094 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain DUF4336 PF14234.1 EAQ89809.1 - 2e-09 37.0 0.0 1.3e-08 34.3 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4336) Amidase PF01425.16 EAQ89810.1 - 3.5e-96 322.7 3.5 1.3e-95 320.8 2.4 1.7 1 1 0 1 1 1 1 Amidase PRP38 PF03371.10 EAQ89811.1 - 3.1e-46 157.1 0.0 6.9e-28 97.4 0.0 2.1 1 1 1 2 2 2 2 PRP38 family PRP38_assoc PF12871.2 EAQ89811.1 - 1.1 9.8 50.3 0.025 15.1 29.9 2.1 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EAQ89811.1 - 1.7 8.3 44.9 3.4 7.3 31.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RAP1 PF07218.6 EAQ89811.1 - 3.3 5.6 6.6 4.2 5.3 4.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.9 EAQ89811.1 - 4.1 5.3 13.8 5.4 4.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EAQ89811.1 - 5.6 6.6 9.5 7.9 6.1 6.6 1.2 1 0 0 1 1 1 0 DDHD domain MmgE_PrpD PF03972.9 EAQ89813.1 - 3.8e-131 437.3 0.0 6e-131 436.6 0.0 1.3 1 1 0 1 1 1 1 MmgE/PrpD family WD40 PF00400.27 EAQ89814.1 - 1.8e-24 84.6 13.7 3.8e-09 36.0 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EAQ89814.1 - 0.023 14.9 0.5 11 6.3 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain PD40 PF07676.7 EAQ89814.1 - 0.025 14.2 0.2 0.025 14.2 0.1 3.3 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat RRM_6 PF14259.1 EAQ89815.1 - 1.5e-06 28.0 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ89815.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89815.1 - 0.047 13.5 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 EAQ89816.1 - 0.0019 18.5 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 SET domain Coq4 PF05019.8 EAQ89817.1 - 6.3e-80 267.2 0.0 7.6e-80 266.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EAQ89818.1 - 8.5e-35 118.9 11.8 1.1e-34 118.6 8.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF927 PF06048.6 EAQ89818.1 - 0.033 13.4 0.3 0.038 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Host_attach PF10116.4 EAQ89818.1 - 0.11 12.7 5.0 0.33 11.1 3.4 1.7 1 1 0 1 1 1 0 Protein required for attachment to host cells Fes1 PF08609.5 EAQ89818.1 - 0.12 12.8 1.4 0.25 11.8 0.2 1.8 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 DUF4615 PF15393.1 EAQ89818.1 - 0.38 10.9 3.9 1 9.5 2.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Alb1 PF09135.6 EAQ89818.1 - 4.2 8.0 6.7 23 5.6 0.2 2.4 1 1 1 2 2 2 0 Alb1 DUF4611 PF15387.1 EAQ89818.1 - 5.5 7.1 6.9 1.2 9.3 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) ApbA_C PF08546.6 EAQ89819.1 - 2.4e-19 69.5 0.0 3.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EAQ89819.1 - 2.4e-16 59.5 0.0 3.4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Peptidase_M90 PF06167.7 EAQ89819.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Sas10_Utp3 PF04000.10 EAQ89820.1 - 1.5e-17 63.5 0.9 2.3e-17 62.9 0.1 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family BLOC1_2 PF10046.4 EAQ89820.1 - 0.052 13.6 0.2 6.9 6.8 0.0 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OHCU_decarbox PF09349.5 EAQ89820.1 - 0.058 13.6 1.3 0.088 13.1 0.9 1.3 1 0 0 1 1 1 0 OHCU decarboxylase DUF2076 PF09849.4 EAQ89821.1 - 3e-09 37.3 10.8 3.8e-09 36.9 7.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EAQ89821.1 - 0.00038 20.2 4.2 0.00057 19.7 2.9 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EAQ89821.1 - 0.018 15.1 0.4 0.031 14.3 0.1 1.4 1 1 0 1 1 1 0 GCK domain DUF759 PF05537.6 EAQ89821.1 - 0.044 12.5 0.3 0.05 12.3 0.2 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Bindin PF02084.10 EAQ89821.1 - 2.2 8.2 7.3 2.9 7.8 5.1 1.2 1 0 0 1 1 1 0 Bindin UBX PF00789.15 EAQ89822.1 - 3.7e-15 55.7 0.0 6.9e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain CAF-1_p150 PF11600.3 EAQ89822.1 - 0.077 12.3 28.0 0.011 15.1 16.4 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 EAQ89822.1 - 2.3 5.8 7.6 3.2 5.3 5.3 1.1 1 0 0 1 1 1 0 Ycf1 SURF1 PF02104.10 EAQ89823.1 - 2.4e-62 210.5 0.2 3e-62 210.2 0.1 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EAQ89824.1 - 3.5e-115 385.5 13.7 4.9e-115 385.0 9.5 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EAQ89824.1 - 1.9e-09 37.5 0.0 3.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAQ89824.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAQ89824.1 - 0.00015 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ras PF00071.17 EAQ89825.1 - 5e-51 172.2 0.0 6e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ89825.1 - 2e-18 66.9 0.0 2.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ89825.1 - 1.9e-06 27.2 0.0 2.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ89825.1 - 0.0048 16.3 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.17 EAQ89826.1 - 4.6e-11 42.2 0.7 1.4e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89826.1 - 1.1e-08 34.9 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb1_6 PF04992.9 EAQ89828.1 - 0.0027 17.4 0.1 0.2 11.4 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 6 Neurensin PF14927.1 EAQ89828.1 - 0.039 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Neurensin Strabismus PF06638.6 EAQ89828.1 - 0.46 8.7 0.0 0.67 8.1 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein Ras PF00071.17 EAQ89830.1 - 4.7e-32 110.6 0.0 9.7e-19 67.3 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EAQ89830.1 - 8.8e-05 22.9 0.0 0.072 13.5 0.0 2.4 1 1 1 2 2 2 2 Miro-like protein Arf PF00025.16 EAQ89830.1 - 0.024 13.8 0.0 0.11 11.7 0.0 1.9 1 1 1 2 2 2 0 ADP-ribosylation factor family DUF4535 PF15054.1 EAQ89831.1 - 0.03 13.7 0.3 0.063 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) CMS1 PF14617.1 EAQ89832.1 - 6.3e-48 163.0 1.4 7.3e-48 162.8 1.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Med19 PF10278.4 EAQ89832.1 - 0.15 11.7 11.1 0.35 10.5 6.9 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 zinc_ribbon_2 PF13240.1 EAQ89833.1 - 0.089 12.3 2.8 1.3 8.6 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PI-PLC-X PF00388.14 EAQ89834.1 - 7e-56 187.6 0.0 1.8e-55 186.3 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAQ89834.1 - 8.2e-36 122.5 0.0 1.4e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain 2OG-FeII_Oxy_3 PF13640.1 EAQ89839.1 - 0.0099 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.7 EAQ89840.1 - 3.4e-178 593.9 0.0 4.3e-178 593.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EAQ89840.1 - 0.014 15.3 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 EAQ89841.1 - 2.3e-47 161.4 0.1 3.6e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAQ89841.1 - 1.1e-33 115.6 0.0 2e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S4e PF00900.15 EAQ89843.1 - 2.8e-31 106.9 0.3 6e-31 105.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EAQ89843.1 - 5e-19 67.8 3.5 1e-18 66.8 2.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EAQ89843.1 - 6.7e-07 28.6 0.0 1.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EAQ89843.1 - 8.3e-05 22.1 0.9 8.3e-05 22.1 0.6 2.9 4 0 0 4 4 4 1 KOW motif Myb_DNA-binding PF00249.26 EAQ89844.1 - 7.5e-15 54.7 0.1 5.7e-09 35.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ89844.1 - 3e-11 43.2 0.1 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_18 PF00704.23 EAQ89845.1 - 3.7e-18 66.1 0.2 3.7e-18 66.1 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 EAQ89845.1 - 2.5e-08 33.6 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain Mid2 PF04478.7 EAQ89846.1 - 3.4e-05 23.3 3.5 3.4e-05 23.3 2.4 1.9 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor DUF605 PF04652.11 EAQ89846.1 - 4 6.7 26.5 6 6.1 18.4 1.3 1 0 0 1 1 1 0 Vta1 like MCPVI PF02993.9 EAQ89846.1 - 7.5 6.6 10.5 10 6.1 7.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI PAM2 PF07145.10 EAQ89848.1 - 8.1e-05 21.8 12.9 0.069 12.6 0.7 4.9 5 0 0 5 5 5 3 Ataxin-2 C-terminal region zf-C2H2 PF00096.21 EAQ89849.1 - 1.2e-10 41.0 10.0 2.4e-05 24.3 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAQ89849.1 - 3.4e-08 33.3 6.2 0.00022 21.3 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ89849.1 - 1.7e-07 31.0 6.6 0.006 16.8 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EAQ89849.1 - 0.027 14.6 2.1 0.027 14.6 1.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain BolA PF01722.13 EAQ89849.1 - 0.047 13.6 0.2 10 6.1 0.0 2.4 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_jaz PF12171.3 EAQ89849.1 - 0.39 10.9 2.8 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ctr PF04145.10 EAQ89850.1 - 2.9e-14 53.3 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family CoA_binding_3 PF13727.1 EAQ89850.1 - 0.068 12.9 0.2 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 CoA-binding domain CW_binding_2 PF04122.7 EAQ89850.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Peptidase_M49 PF03571.10 EAQ89850.1 - 0.16 10.0 0.0 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M49 SRF-TF PF00319.13 EAQ89851.1 - 3.6e-23 80.5 0.2 5.2e-23 80.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tetraspannin PF00335.15 EAQ89853.1 - 3e-07 29.9 5.3 4.1e-07 29.5 3.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Srg PF02118.16 EAQ89853.1 - 0.0041 16.6 0.9 0.0048 16.3 0.2 1.5 2 0 0 2 2 2 1 Srg family chemoreceptor Cation_ATPase_C PF00689.16 EAQ89853.1 - 0.022 14.2 0.3 0.022 14.2 0.2 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus ABA_GPCR PF12430.3 EAQ89853.1 - 0.022 13.8 0.7 0.044 12.9 0.5 1.7 1 1 0 1 1 1 0 Abscisic acid G-protein coupled receptor DUF3366 PF11846.3 EAQ89853.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF2207 PF09972.4 EAQ89853.1 - 0.06 11.9 0.8 0.084 11.4 0.3 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4149 PF13664.1 EAQ89853.1 - 0.1 12.6 2.2 0.27 11.2 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF373 PF04123.8 EAQ89853.1 - 0.12 11.3 0.4 0.14 11.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4577 PF15145.1 EAQ89853.1 - 0.12 12.2 0.0 0.76 9.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) Mg_trans_NIPA PF05653.9 EAQ89854.1 - 3.1e-16 59.2 4.4 4.8e-16 58.5 3.1 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EAQ89854.1 - 2.1e-06 27.7 11.8 0.00057 19.9 0.2 2.5 2 0 0 2 2 2 2 EamA-like transporter family vATP-synt_E PF01991.13 EAQ89855.1 - 4.5e-64 215.3 3.8 5.2e-64 215.1 2.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.11 EAQ89855.1 - 0.044 13.6 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Flagellar assembly protein FliH MRP-63 PF14978.1 EAQ89855.1 - 0.15 12.5 1.9 0.35 11.3 1.3 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 IL10 PF00726.12 EAQ89856.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin 10 HrpA_pilin PF09589.5 EAQ89857.1 - 0.061 13.7 0.3 0.096 13.1 0.2 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein bPH_3 PF14470.1 EAQ89857.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain E1-E2_ATPase PF00122.15 EAQ89858.1 - 9.6e-14 50.9 0.3 4.6e-13 48.7 0.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EAQ89858.1 - 4.6e-13 48.9 0.0 1.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAQ89858.1 - 1.1e-10 41.9 0.1 4e-10 40.1 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ89858.1 - 9.8e-10 39.2 3.3 4.1e-07 30.6 2.3 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ89858.1 - 0.035 13.6 0.6 0.086 12.3 0.4 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.17 EAQ89859.1 - 5.7e-114 380.9 0.1 6.9e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATA PF00320.22 EAQ89860.1 - 1.7e-16 59.2 1.9 3.3e-16 58.3 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EAQ89860.1 - 6.5e-12 44.8 1.7 1.1e-11 44.0 1.2 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Hist_rich_Ca-bd PF10529.4 EAQ89861.1 - 0.13 12.3 9.9 0.22 11.5 6.9 1.4 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region Pkinase_C PF00433.19 EAQ89862.1 - 3.6e-07 30.6 0.2 5.9e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Tricorn_C1 PF14684.1 EAQ89862.1 - 0.03 14.1 1.2 0.061 13.1 0.1 1.8 1 1 1 2 2 2 0 Tricorn protease C1 domain Pkinase PF00069.20 EAQ89863.1 - 9.3e-39 133.1 0.0 1.3e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89863.1 - 1.1e-20 73.7 0.0 1.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89863.1 - 0.00043 19.3 0.1 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAQ89863.1 - 0.0024 17.6 0.5 0.044 13.4 0.0 2.6 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EAQ89863.1 - 0.05 12.6 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EAQ89863.1 - 0.17 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Wbp11 PF09429.5 EAQ89864.1 - 2.4e-23 81.8 12.3 2.4e-23 81.8 8.5 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2294 PF10057.4 EAQ89864.1 - 0.1 12.2 0.2 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Lipoprotein_7 PF01540.11 EAQ89864.1 - 0.28 10.2 4.6 0.44 9.5 3.2 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein DUF3450 PF11932.3 EAQ89864.1 - 1.1 8.5 6.1 1.6 7.9 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3306 PF11748.3 EAQ89864.1 - 6.7 7.3 11.1 12 6.6 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) ApbA PF02558.11 EAQ89865.1 - 1.7e-23 82.7 0.0 2.5e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EAQ89865.1 - 3.4e-18 65.8 0.0 5.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.24 EAQ89866.1 - 5.1e-38 130.2 0.1 8.2e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ89866.1 - 3.1e-24 84.6 0.0 6.1e-23 80.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ89866.1 - 7.7e-07 29.1 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EAQ89866.1 - 0.058 12.4 0.0 0.27 10.2 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Cyclin PF08613.6 EAQ89867.1 - 3.5e-13 50.2 1.2 4.1e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EAQ89867.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain CorA PF01544.13 EAQ89869.1 - 1.4e-13 50.5 0.7 2.4e-13 49.7 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.12 EAQ89869.1 - 0.0034 16.9 0.1 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Transposase PWWP PF00855.12 EAQ89870.1 - 0.02 15.0 0.1 0.043 14.0 0.1 1.5 1 0 0 1 1 1 0 PWWP domain Ribosomal_S30 PF04758.9 EAQ89871.1 - 1.7e-29 101.3 8.0 1.9e-29 101.1 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pyrid_oxidase_2 PF13883.1 EAQ89872.1 - 8.8e-41 139.4 0.0 1.5e-40 138.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Robl_LC7 PF03259.12 EAQ89874.1 - 4e-10 39.1 0.0 4.3e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 EAQ89875.1 - 1.3e-06 28.3 1.6 3.1e-06 27.0 0.0 2.3 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation DUF4519 PF15012.1 EAQ89875.1 - 2.1 8.3 6.3 4.1 7.4 3.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DEAD PF00270.24 EAQ89876.1 - 4.5e-35 120.6 0.0 7.6e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ89876.1 - 2e-19 69.2 0.3 4.8e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAQ89876.1 - 7.9e-06 24.8 0.0 1.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EAQ89876.1 - 0.0019 17.5 0.1 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 SecA DEAD-like domain DUF1253 PF06862.7 EAQ89876.1 - 0.0023 16.4 0.0 0.25 9.7 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) Acatn PF13000.2 EAQ89877.1 - 7.9e-132 440.5 19.0 6.3e-77 259.3 4.3 3.0 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 EAQ89878.1 - 4.1e-24 84.6 0.0 9.5e-24 83.4 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Pox_A_type_inc PF04508.7 EAQ89878.1 - 0.0097 15.6 0.2 0.06 13.1 0.1 2.4 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat Securin PF04856.8 EAQ89878.1 - 0.062 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor DivIVA PF05103.8 EAQ89878.1 - 0.1 12.6 2.6 0.2 11.7 1.8 1.4 1 0 0 1 1 1 0 DivIVA protein AIP3 PF03915.8 EAQ89878.1 - 0.13 11.1 2.2 0.17 10.7 1.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 MFS_1 PF07690.11 EAQ89880.1 - 8.4e-39 133.2 29.6 1.8e-33 115.7 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ89880.1 - 8.2e-07 27.9 7.7 8.2e-07 27.9 5.4 1.9 2 2 0 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 EAQ89880.1 - 3.9e-05 22.5 0.9 5.7e-05 21.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 EAQ89880.1 - 6.1e-05 21.5 4.1 6.1e-05 21.5 2.9 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EAQ89880.1 - 0.0028 17.3 1.0 0.3 10.8 0.0 3.0 2 0 0 2 2 2 1 MFS_1 like family DUF3621 PF12285.3 EAQ89880.1 - 0.31 11.2 1.7 10 6.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3621) PTCB-BRCT PF12738.2 EAQ89881.1 - 4e-11 42.5 0.0 9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EAQ89881.1 - 4.1e-10 39.6 0.0 7.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EAQ89881.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain Dicty_REP PF05086.7 EAQ89881.1 - 3.1 5.4 6.1 4.2 4.9 4.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DFP PF04127.10 EAQ89882.1 - 1e-14 54.5 0.0 5.1e-06 26.2 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein eIF-1a PF01176.14 EAQ89884.1 - 5.5e-23 80.1 0.0 7.5e-23 79.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EAQ89885.1 - 2.5e-29 101.2 0.2 3.4e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EAQ89885.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 WH2 motif Ribosomal_60s PF00428.14 EAQ89885.1 - 0.29 11.5 0.1 0.29 11.5 0.1 3.6 5 1 0 5 5 5 0 60s Acidic ribosomal protein ERCC4 PF02732.10 EAQ89887.1 - 2.3e-24 85.7 0.0 5.2e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Glycoprotein_B PF00606.13 EAQ89888.1 - 0.0045 15.0 1.4 0.0049 14.9 1.0 1.0 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B AAA_23 PF13476.1 EAQ89889.1 - 8.7e-19 68.6 0.2 8.7e-19 68.6 0.1 4.4 2 1 0 3 3 3 1 AAA domain SMC_N PF02463.14 EAQ89889.1 - 4.3e-15 55.5 17.1 5.7e-14 51.8 2.8 4.2 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ89889.1 - 0.00025 21.1 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAQ89889.1 - 0.0035 16.8 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EAQ89889.1 - 0.023 13.7 0.1 0.023 13.7 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EAQ89889.1 - 0.025 14.7 0.4 0.6 10.3 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_4 PF02056.11 EAQ89889.1 - 0.026 13.8 1.0 11 5.3 0.1 3.3 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase Pox_A_type_inc PF04508.7 EAQ89889.1 - 0.043 13.6 6.5 0.53 10.2 0.0 4.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF258 PF03193.11 EAQ89889.1 - 0.05 12.7 0.0 0.16 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAQ89889.1 - 0.51 9.7 0.0 0.51 9.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.20 EAQ89890.1 - 7.6e-75 251.4 0.0 1.2e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89890.1 - 1.6e-37 128.9 0.3 7.3e-35 120.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89890.1 - 6.7e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ89890.1 - 0.00062 18.8 0.0 0.002 17.2 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EAQ89890.1 - 0.0014 18.2 0.2 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EAQ89890.1 - 0.0016 18.2 0.6 0.0095 15.6 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lyase_1 PF00206.15 EAQ89891.1 - 5.1e-69 232.8 0.0 8e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EAQ89891.1 - 1e-22 79.9 0.1 2.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Malate_synthase PF01274.17 EAQ89892.1 - 4.6e-78 262.5 0.0 5.5e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.17 EAQ89893.1 - 1.1e-62 211.7 0.9 8.9e-62 208.7 0.6 1.9 1 1 0 1 1 1 1 Malate synthase Amidase PF01425.16 EAQ89894.1 - 2.1e-85 287.2 0.6 2.7e-85 286.8 0.4 1.1 1 0 0 1 1 1 1 Amidase ACT_7 PF13840.1 EAQ89894.1 - 0.15 11.6 0.7 0.42 10.1 0.1 2.0 2 0 0 2 2 2 0 ACT domain DASH_Spc34 PF08657.5 EAQ89895.1 - 0.029 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 SEN1_N PF12726.2 EAQ89896.1 - 4.4e-206 686.2 0.0 5.5e-206 685.9 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EAQ89896.1 - 6.6e-70 235.3 0.3 6.6e-70 235.3 0.2 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EAQ89896.1 - 9.5e-63 211.1 0.0 1.7e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ89896.1 - 7.4e-11 41.6 0.4 2.5e-10 39.9 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAQ89896.1 - 1.2e-08 34.7 0.3 5.7e-06 26.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EAQ89896.1 - 5.1e-06 26.0 0.0 0.00083 18.7 0.0 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EAQ89896.1 - 1.3e-05 24.8 0.4 0.013 15.0 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EAQ89896.1 - 0.012 15.0 0.3 0.093 12.2 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EAQ89896.1 - 0.057 12.8 1.3 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 EAQ89897.1 - 3.2e-08 33.8 0.0 9.8e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.12 EAQ89899.1 - 4.7e-39 134.4 0.0 8.2e-30 104.0 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase EAF PF09816.4 EAQ89900.1 - 5.8e-23 80.9 0.3 1.1e-22 80.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor CBM_6 PF03422.10 EAQ89900.1 - 0.046 13.8 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) Hid1 PF12722.2 EAQ89900.1 - 0.44 8.1 1.1 0.58 7.7 0.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_76 PF03663.9 EAQ89901.1 - 3.2e-145 484.1 18.6 4.3e-145 483.7 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.17 EAQ89901.1 - 3.6e-61 207.1 0.0 5.1e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_2 PF02230.11 EAQ89905.1 - 4e-62 209.4 0.0 4.7e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAQ89905.1 - 1.5e-12 47.5 0.0 4.2e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ89905.1 - 1.6e-09 37.9 0.1 4.4e-05 23.4 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EAQ89905.1 - 5.9e-06 25.8 0.0 2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EAQ89905.1 - 6.1e-06 25.6 0.7 0.00047 19.4 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EAQ89905.1 - 0.00088 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EAQ89905.1 - 0.018 14.6 0.0 0.076 12.5 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EAQ89905.1 - 0.087 11.3 0.2 0.14 10.6 0.1 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) LigB PF02900.13 EAQ89906.1 - 6.6e-55 185.9 0.1 7.4e-55 185.8 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TRI12 PF06609.8 EAQ89907.1 - 3.4e-30 104.8 27.8 4.1e-30 104.5 19.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EAQ89907.1 - 6.8e-18 64.5 51.7 6.8e-18 64.5 35.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ89907.1 - 1.1e-09 37.4 15.1 1.1e-09 37.4 10.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Ferric_reduct PF01794.14 EAQ89908.1 - 1.7e-15 57.1 2.4 1.7e-15 57.1 1.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EAQ89908.1 - 3.6e-14 52.4 0.0 8.9e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EAQ89908.1 - 4.2e-14 52.7 0.0 2.8e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EAQ89908.1 - 0.00041 20.8 0.0 0.077 13.5 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DAO PF01266.19 EAQ89909.1 - 1.3e-33 116.4 0.3 2.2e-33 115.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ89909.1 - 0.00015 22.1 0.0 0.033 14.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ89909.1 - 0.0017 18.3 0.0 0.009 16.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAQ89909.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EAQ89909.1 - 0.085 12.7 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EAQ89909.1 - 0.1 11.2 0.0 9.2 4.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.20 EAQ89910.1 - 7.8e-26 90.9 4.5 2.8e-24 85.9 3.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ89910.1 - 7.9e-16 58.5 0.1 6.5e-07 29.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ89910.1 - 1.4e-09 37.8 4.5 2.3e-07 30.6 3.1 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAQ89910.1 - 1.7e-06 28.1 1.0 2.2e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EAQ89910.1 - 0.0019 17.6 0.2 0.0089 15.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EAQ89910.1 - 0.0048 17.2 0.4 0.014 15.8 0.0 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EAQ89910.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain CoA_binding_2 PF13380.1 EAQ89910.1 - 0.034 14.3 0.1 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain PP2C_2 PF13672.1 EAQ89910.1 - 0.086 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C ADH_zinc_N PF00107.21 EAQ89910.1 - 0.088 12.3 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CBFD_NFYB_HMF PF00808.18 EAQ89911.1 - 2e-13 50.1 0.7 3.9e-13 49.2 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAQ89911.1 - 0.00083 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Spidroin_MaSp PF11260.3 EAQ89911.1 - 0.1 12.7 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 zf-DHHC PF01529.15 EAQ89913.1 - 1.7e-37 128.4 4.4 1.7e-37 128.4 3.1 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 EAQ89913.1 - 0.0029 17.1 1.0 0.0029 17.1 0.7 2.1 2 0 0 2 2 2 1 Yip1 domain Complex1_LYR_1 PF13232.1 EAQ89914.1 - 1e-15 57.6 0.8 2e-15 56.7 0.6 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EAQ89914.1 - 2.1e-14 53.0 0.8 2.1e-14 53.0 0.6 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Fungal_trans PF04082.13 EAQ89915.1 - 6.7e-11 41.5 0.1 1.2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ89915.1 - 0.0022 17.8 7.8 0.0036 17.1 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.17 EAQ89917.1 - 4e-15 54.4 7.1 0.00048 19.9 0.0 9.7 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.1 EAQ89917.1 - 7.7e-14 51.7 13.1 2.2e-06 27.8 0.0 7.9 3 1 4 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EAQ89917.1 - 1e-11 44.9 12.4 7.1e-07 29.5 0.0 8.5 9 3 3 12 12 12 1 HEAT-like repeat IBN_N PF03810.14 EAQ89917.1 - 5.3e-08 32.6 6.3 7.4e-08 32.2 1.1 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EAQ89917.1 - 0.00075 18.9 2.5 9.8 5.4 0.0 5.0 4 1 2 6 6 6 1 CLASP N terminal Arm PF00514.18 EAQ89917.1 - 0.0032 17.2 1.4 1.2 9.0 0.0 4.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cse1 PF08506.5 EAQ89917.1 - 0.013 14.0 0.0 2 6.9 0.0 3.2 3 0 0 3 3 3 0 Cse1 Cohesin_HEAT PF12765.2 EAQ89917.1 - 0.033 14.1 0.0 5.3 7.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.11 EAQ89917.1 - 0.056 13.9 1.0 74 4.2 0.0 5.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat PI3Ka PF00613.15 EAQ89917.1 - 0.056 12.6 0.0 0.91 8.6 0.0 2.8 4 0 0 4 4 4 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) HMGL-like PF00682.14 EAQ89918.1 - 2.2e-63 214.1 0.0 3e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EAQ89918.1 - 5.6e-15 55.3 0.1 6e-14 51.9 0.1 2.5 1 1 1 2 2 2 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.14 EAQ89919.1 - 2.6e-20 72.7 9.1 2.6e-20 72.7 6.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EAQ89919.1 - 1.2e-17 64.2 0.0 1.4e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAQ89919.1 - 2e-12 46.8 0.0 7.9e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain DUF1690 PF07956.6 EAQ89921.1 - 3.2e-33 114.6 4.2 3.9e-33 114.4 2.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) AAA_13 PF13166.1 EAQ89921.1 - 0.0047 15.4 1.3 0.0057 15.1 0.9 1.1 1 0 0 1 1 1 1 AAA domain PAP_central PF04928.12 EAQ89921.1 - 0.074 11.8 0.7 0.095 11.4 0.5 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain FUSC PF04632.7 EAQ89921.1 - 0.19 10.1 7.8 0.2 10.0 5.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSCB_C PF07743.8 EAQ89921.1 - 3.5 8.1 10.4 6 7.4 2.7 2.9 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain TYW3 PF02676.9 EAQ89922.1 - 1.5e-66 223.4 0.0 2.1e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Fasciclin PF02469.17 EAQ89922.1 - 1.7e-40 137.9 0.5 5.9e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain PAPS_reduct PF01507.14 EAQ89923.1 - 6.6e-43 146.5 0.0 8.4e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Hydrolase_3 PF08282.7 EAQ89924.1 - 8.4e-10 38.6 0.1 7.7e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAQ89924.1 - 6.3e-07 29.7 0.1 0.00095 19.3 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ89924.1 - 0.00044 20.7 3.0 0.009 16.4 0.2 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EAQ89924.1 - 0.00085 18.3 0.1 0.0012 17.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.8 EAQ89924.1 - 0.042 13.1 0.1 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.7 EAQ89924.1 - 0.052 12.7 0.1 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase_like PF13242.1 EAQ89924.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Acid_PPase PF12689.2 EAQ89924.1 - 0.14 11.7 0.1 0.28 10.8 0.1 1.5 1 1 0 1 1 1 0 Acid Phosphatase GTP_EFTU PF00009.22 EAQ89925.1 - 6.7e-57 191.9 0.0 9.4e-57 191.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAQ89925.1 - 8.2e-37 125.3 0.1 2.2e-36 123.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAQ89925.1 - 6.9e-18 64.5 1.3 6.9e-18 64.5 0.9 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EAQ89925.1 - 0.00016 21.2 0.3 0.00045 19.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EAQ89925.1 - 0.00056 19.8 0.4 0.0016 18.4 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.1 EAQ89926.1 - 1.2e-42 145.7 0.1 1.7e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Trypan_PARP PF05887.6 EAQ89926.1 - 0.23 11.2 8.4 0.75 9.6 5.9 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 EAQ89926.1 - 0.39 9.0 2.9 0.81 7.9 2.0 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PLRV_ORF5 PF01690.12 EAQ89926.1 - 5.8 5.9 8.2 11 5.0 5.7 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MAGE PF01454.14 EAQ89927.1 - 7.4e-40 136.3 0.0 1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.6 EAQ89928.1 - 5.9e-42 141.3 0.0 7.1e-42 141.1 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.13 EAQ89929.1 - 0.00051 19.8 12.9 0.07 13.0 3.2 3.1 3 0 0 3 3 3 2 MYND finger DUF3186 PF11382.3 EAQ89929.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Septin PF00735.13 EAQ89930.1 - 1.9e-32 112.4 0.0 1.3e-11 44.1 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_18 PF13238.1 EAQ89930.1 - 0.0052 17.0 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EAQ89930.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 EAQ89930.1 - 0.0088 14.7 0.0 0.015 14.0 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 EAQ89930.1 - 0.018 15.8 0.0 0.082 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EAQ89930.1 - 0.024 14.9 0.2 0.036 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EAQ89930.1 - 0.033 14.1 0.0 0.085 12.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EAQ89930.1 - 0.054 13.9 0.1 0.18 12.3 0.0 2.0 2 1 0 2 2 2 0 Miro-like protein Pox_A32 PF04665.7 EAQ89930.1 - 0.081 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 EAQ89930.1 - 0.089 12.0 0.1 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EAQ89930.1 - 0.093 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EAQ89930.1 - 0.1 12.2 0.5 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EAQ89930.1 - 0.12 12.1 0.7 0.57 9.9 0.1 2.3 3 0 0 3 3 3 0 Dynamin family ABC1 PF03109.11 EAQ89932.1 - 8.7e-09 35.3 0.0 5.2e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EAQ89932.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.7 EAQ89933.1 - 7.9e-16 58.2 15.7 4.4e-15 55.8 5.8 2.1 2 0 0 2 2 2 2 SUR7/PalI family NfeD PF01957.13 EAQ89933.1 - 0.015 15.4 3.6 0.015 15.4 2.5 2.0 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2678 PF10856.3 EAQ89933.1 - 0.38 10.4 2.7 0.9 9.2 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) bZIP_1 PF00170.16 EAQ89935.1 - 1.4e-07 31.3 16.5 2.8e-07 30.3 11.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EAQ89935.1 - 0.064 13.5 14.9 0.096 12.9 10.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Glutaredoxin2_C PF04399.8 EAQ89935.1 - 0.091 12.3 2.0 0.16 11.5 1.4 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Dynactin_p62 PF05502.8 EAQ89935.1 - 0.14 10.8 6.2 0.2 10.4 4.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family Vac_Fusion PF02346.11 EAQ89935.1 - 0.17 11.3 2.3 0.3 10.5 1.6 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein IFP_35_N PF07334.8 EAQ89935.1 - 0.17 11.8 1.3 0.36 10.8 0.6 1.8 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus V_ATPase_I PF01496.14 EAQ89935.1 - 0.2 9.4 1.5 0.25 9.1 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 EAQ89935.1 - 0.26 11.1 13.5 8.1 6.3 10.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 EAQ89935.1 - 0.71 9.8 3.2 1.4 8.8 2.2 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EAQ89935.1 - 0.97 9.8 6.7 0.34 11.2 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GvpL_GvpF PF06386.6 EAQ89935.1 - 1.2 8.6 7.5 3.7 7.0 5.0 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 EAQ89935.1 - 1.3 8.8 25.6 0.25 11.2 12.5 2.5 2 1 1 3 3 3 0 Basic region leucine zipper CDP-OH_P_transf PF01066.16 EAQ89936.1 - 1.5e-15 57.3 4.7 1.5e-15 57.3 3.2 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.15 EAQ89937.1 - 1.7e-115 386.3 1.9 2.2e-115 386.0 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EAQ89937.1 - 9.4e-58 194.3 3.6 1.9e-57 193.3 2.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EAQ89937.1 - 2.6e-15 56.4 0.6 2.4e-05 24.5 0.1 6.0 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 EAQ89937.1 - 0.0002 21.5 0.2 0.98 10.0 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EAQ89937.1 - 0.019 14.3 0.2 0.019 14.3 0.1 2.8 3 1 0 3 3 3 0 CLASP N terminal MRP-S35 PF10246.4 EAQ89937.1 - 0.069 13.0 0.0 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Alpha_adaptin_C PF02296.11 EAQ89937.1 - 0.096 12.6 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EAQ89937.1 - 0.14 12.6 3.0 0.8 10.2 0.7 3.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.17 EAQ89937.1 - 0.29 11.3 8.7 2 8.7 0.2 4.7 5 0 0 5 5 5 0 HEAT repeat Myb_DNA-bind_6 PF13921.1 EAQ89938.1 - 0.0053 16.8 0.2 0.023 14.7 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain UPF0016 PF01169.14 EAQ89939.1 - 9.7e-43 144.1 26.0 5e-22 77.8 5.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Voldacs PF03517.8 EAQ89941.1 - 0.07 12.9 4.0 0.14 12.0 2.7 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling CENP-B_dimeris PF09026.5 EAQ89941.1 - 0.097 12.9 12.2 0.27 11.5 8.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EAQ89941.1 - 1.5 8.3 10.7 2.4 7.7 7.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 EAQ89941.1 - 2.5 7.1 9.4 4.7 6.2 6.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region ATP-sulfurylase PF01747.12 EAQ89942.1 - 1.8e-88 295.4 0.0 2.4e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EAQ89942.1 - 5.6e-58 195.0 0.0 8.7e-58 194.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EAQ89942.1 - 1.5e-52 177.2 0.0 2.3e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EAQ89942.1 - 0.14 12.0 0.2 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain TRP PF06011.7 EAQ89944.1 - 2.7e-104 349.2 12.5 3.5e-104 348.8 8.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAQ89944.1 - 4.9e-25 88.2 0.0 7.4e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Dioxygenase_C PF00775.16 EAQ89945.1 - 2.7e-42 144.1 0.0 3.7e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EAQ89945.1 - 2.9e-17 62.4 0.0 4.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EAQ89945.1 - 2.2e-05 24.4 0.0 5.5e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.6 EAQ89945.1 - 0.07 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) AdoMet_MTase PF07757.8 EAQ89946.1 - 1.4e-38 131.4 0.0 2.4e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EAQ89946.1 - 0.033 13.9 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EAQ89946.1 - 0.1 12.2 0.2 1.2 8.8 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ89946.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 EAQ89947.1 - 3.3e-29 100.5 2.8 4.7e-29 100.0 1.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EAQ89947.1 - 0.033 14.2 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) DUF2575 PF10837.3 EAQ89947.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Ocnus PF05005.10 EAQ89947.1 - 0.093 12.6 0.8 0.13 12.0 0.2 1.5 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) EOS1 PF12326.3 EAQ89948.1 - 4.2e-24 84.8 8.9 1e-20 73.8 1.1 2.2 1 1 1 2 2 2 2 N-glycosylation protein DUF4396 PF14342.1 EAQ89948.1 - 2.7 8.1 5.0 27 4.8 4.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) SSF PF00474.12 EAQ89949.1 - 1.1e-10 40.7 22.2 4.3e-10 38.8 15.4 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 EAQ89950.1 - 5.4e-25 86.8 0.1 1.4e-15 56.6 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ89950.1 - 1.7e-15 56.7 0.2 3.2e-11 43.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ89950.1 - 3.2e-13 49.2 0.0 1.9e-07 30.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3678 PF12435.3 EAQ89951.1 - 0.028 13.9 3.5 0.028 13.9 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) CIA30 PF08547.7 EAQ89952.1 - 4.9e-46 156.4 0.0 6.7e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) JmjC PF02373.17 EAQ89954.1 - 4e-17 62.5 0.0 7.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.23 EAQ89954.1 - 7.8e-10 39.2 0.1 2.8e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 SET domain IncA PF04156.9 EAQ89955.1 - 0.0057 16.2 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 IncA protein BLOC1_2 PF10046.4 EAQ89955.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EAQ89955.1 - 2.1 7.9 3.8 42 3.7 0.0 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 EAQ89955.1 - 5.9 7.3 9.3 13 6.3 0.9 3.4 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Thioredoxin PF00085.15 EAQ89956.1 - 3.6e-06 26.5 0.0 5.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.6 EAQ89956.1 - 0.055 12.9 0.2 0.48 9.8 0.1 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 EAQ89956.1 - 0.16 12.2 0.0 2.4 8.3 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.5 EAQ89956.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin MFS_1 PF07690.11 EAQ89957.1 - 4.1e-43 147.4 29.9 3.3e-31 108.3 7.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ89957.1 - 2.5e-13 49.4 10.9 2.5e-13 49.4 7.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TFIIA PF03153.8 EAQ89957.1 - 5 6.9 6.2 7.4 6.3 4.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2348 PF09807.4 EAQ89958.1 - 0.0039 16.3 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) BAF1_ABF1 PF04684.8 EAQ89958.1 - 0.83 8.4 5.8 0.17 10.6 0.6 2.1 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_L37e PF01907.14 EAQ89959.1 - 7.5e-26 89.6 12.8 1.1e-25 89.1 8.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EAQ89959.1 - 0.0031 17.2 1.5 0.0046 16.7 1.1 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EAQ89959.1 - 0.033 13.8 0.2 0.043 13.5 0.2 1.3 1 1 0 1 1 1 0 SelR domain zf-ribbon_3 PF13248.1 EAQ89959.1 - 0.099 11.8 1.7 0.17 11.1 1.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4 PF00097.20 EAQ89959.1 - 0.58 9.8 2.8 0.95 9.1 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1 PF00133.17 EAQ89960.1 - 5.3e-225 747.9 0.0 4.3e-224 744.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAQ89960.1 - 3.8e-36 124.1 0.0 1.2e-35 122.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAQ89960.1 - 7.1e-17 61.1 0.6 0.00025 19.8 0.1 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EAQ89960.1 - 2.1e-11 43.4 0.1 5.6e-08 32.3 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EAQ89960.1 - 0.005 15.9 0.0 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-RING_2 PF13639.1 EAQ89961.1 - 7.4e-14 51.3 5.4 1.2e-13 50.6 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EAQ89961.1 - 5.4e-11 42.0 0.0 1.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EAQ89961.1 - 1.6e-09 37.6 5.4 2.6e-09 36.9 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAQ89961.1 - 6.3e-09 35.8 4.3 1.2e-08 34.9 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAQ89961.1 - 1.4e-08 34.2 3.5 2.3e-08 33.5 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ89961.1 - 5.6e-08 32.3 3.9 8.6e-08 31.7 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ89961.1 - 2.4e-07 30.3 3.3 3.7e-07 29.7 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAQ89961.1 - 0.0011 18.7 2.6 0.0032 17.2 1.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EAQ89961.1 - 0.0022 17.8 2.3 0.02 14.7 0.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EAQ89961.1 - 0.058 13.3 3.0 0.19 11.6 2.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EAQ89961.1 - 0.089 12.5 3.0 0.21 11.3 2.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EAQ89961.1 - 0.1 12.6 3.9 0.2 11.7 2.7 1.5 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 EAQ89961.1 - 0.19 11.5 0.5 0.34 10.7 0.4 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.3 EAQ89961.1 - 0.58 9.7 2.4 1.2 8.7 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EAQ89961.1 - 0.58 9.7 3.0 1.1 8.9 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EAQ89961.1 - 1.3 8.7 3.5 2.5 7.8 2.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EAQ89961.1 - 1.7 8.7 3.4 3.3 7.7 2.4 1.5 1 0 0 1 1 1 0 RING-like domain Apc5 PF12862.2 EAQ89962.1 - 7.1e-30 102.7 4.3 1.4e-29 101.7 0.5 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 EAQ89962.1 - 0.031 14.6 4.1 1.8 8.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ89962.1 - 0.081 13.6 14.4 17 6.3 0.1 7.4 6 2 2 8 8 8 0 Tetratricopeptide repeat COX6A PF02046.10 EAQ89963.1 - 2.8e-38 130.4 2.6 3.1e-38 130.2 1.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EAQ89964.1 - 6.4e-16 58.0 0.0 2.1e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ89964.1 - 1.2e-15 58.1 0.0 2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EAQ89964.1 - 5.5e-05 23.0 1.7 0.00014 21.7 1.2 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 EAQ89965.1 - 9.2e-19 67.4 0.1 1.4e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EAQ89967.1 - 2.3e-58 196.8 0.0 5.3e-58 195.6 0.0 1.5 2 0 0 2 2 2 1 Mating-type protein MAT alpha 1 ANTH PF07651.11 EAQ89968.1 - 3.8e-79 265.3 0.1 1.5e-78 263.3 0.0 2.1 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EAQ89968.1 - 4e-64 215.1 7.5 4e-64 215.1 5.2 3.9 5 0 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 EAQ89968.1 - 0.011 15.6 0.0 0.042 13.7 0.0 2.1 1 0 0 1 1 1 0 ENTH domain TP6A_N PF04406.9 EAQ89968.1 - 0.021 14.4 0.1 8.1 6.1 0.0 3.2 3 0 0 3 3 3 0 Type IIB DNA topoisomerase V_ATPase_I PF01496.14 EAQ89968.1 - 1.7 6.3 17.7 0.065 11.0 1.0 2.5 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EAQ89968.1 - 4 6.5 19.6 0.1 11.7 0.6 4.0 3 1 0 4 4 4 0 Reovirus sigma C capsid protein Autophagy_N PF03986.8 EAQ89969.1 - 7.8e-46 155.4 0.6 1.2e-45 154.8 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EAQ89969.1 - 8.9e-23 80.2 0.8 2.6e-22 78.7 0.2 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EAQ89969.1 - 1.4e-05 24.1 0.3 3.7e-05 22.7 0.2 1.8 1 1 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-C3HC4_2 PF13923.1 EAQ89970.1 - 9.4e-09 35.1 8.5 1.8e-08 34.2 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ89970.1 - 1.3e-08 34.3 4.3 2e-08 33.7 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ89970.1 - 2.5e-07 30.2 7.6 4.4e-07 29.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ89970.1 - 2.9e-07 30.2 6.1 4.7e-07 29.5 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAQ89970.1 - 3.3e-07 29.9 6.7 5.3e-07 29.2 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH PF00642.19 EAQ89970.1 - 5.1e-06 26.0 1.7 1e-05 25.0 1.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.1 EAQ89970.1 - 0.00055 19.5 2.4 0.0015 18.2 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAQ89970.1 - 0.00059 19.6 7.2 0.0013 18.5 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Harakiri PF15196.1 EAQ89970.1 - 0.21 11.8 3.4 0.26 11.5 1.3 2.0 2 0 0 2 2 2 0 Activator of apoptosis harakiri Prok-RING_4 PF14447.1 EAQ89970.1 - 1.1 8.8 4.9 2.4 7.7 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mcp5_PH PF12814.2 EAQ89971.1 - 2.6e-43 146.8 1.8 5.1e-43 145.8 0.0 2.2 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1202 PF06717.6 EAQ89971.1 - 0.069 12.4 1.6 0.14 11.3 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) HisKA PF00512.20 EAQ89972.1 - 0.14 12.1 0.1 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DNA_pol_B PF00136.16 EAQ89973.1 - 1.5e-92 310.8 0.0 2.1e-92 310.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EAQ89973.1 - 1.4e-23 83.3 0.0 9.7e-12 44.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EAQ89973.1 - 4e-10 39.5 0.1 1.1e-09 38.1 0.1 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.5 EAQ89973.1 - 0.045 13.6 0.3 0.16 11.8 0.2 1.9 1 0 0 1 1 1 0 XkdW protein Slu7 PF11708.3 EAQ89974.1 - 5.9e-70 235.7 12.0 8.6e-70 235.1 8.3 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EAQ89974.1 - 0.00064 19.3 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EAQ89974.1 - 0.012 15.4 3.0 0.022 14.6 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EAQ89974.1 - 0.04 13.5 4.2 0.1 12.2 2.9 1.6 1 0 0 1 1 1 0 Zinc knuckle MAGE_N PF12440.3 EAQ89974.1 - 4.6 7.5 9.4 1.4 9.2 0.4 2.8 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal Ribosomal_S4 PF00163.14 EAQ89975.1 - 2.1e-27 95.3 1.8 2.6e-27 95.0 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EAQ89975.1 - 2.3e-13 49.3 1.7 2.3e-13 49.3 1.2 2.2 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EAQ89976.1 - 4.3e-40 135.5 4.2 4.3e-40 135.5 2.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3865 PF12981.2 EAQ89976.1 - 0.14 11.9 0.1 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) DUF2404 PF10296.4 EAQ89977.1 - 2.2e-29 101.4 0.0 5.2e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EAQ89977.1 - 0.036 14.2 0.2 0.22 11.7 0.0 2.4 2 1 0 2 2 2 0 PH domain ISN1 PF06437.6 EAQ89980.1 - 4.4e-172 572.4 0.0 4.9e-172 572.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF4238 PF14022.1 EAQ89981.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Pkinase PF00069.20 EAQ89985.1 - 2.6e-55 187.4 0.0 3.8e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89985.1 - 5.4e-26 91.2 0.1 2.4e-25 89.1 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ89985.1 - 0.09 11.7 0.2 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like IBN_N PF03810.14 EAQ89986.1 - 2.8e-13 49.5 3.3 4.3e-10 39.3 0.0 4.5 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 EAQ89986.1 - 1.4e-07 30.4 0.1 3.7e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 EAQ89986.1 - 2.2e-07 30.8 1.3 4.6e-05 23.3 0.1 4.1 4 0 0 4 4 4 1 Exportin 1-like protein DUF2435 PF10363.4 EAQ89986.1 - 0.014 15.3 0.4 0.042 13.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) IMS PF00817.15 EAQ89989.1 - 1.1e-25 90.2 0.0 1.7e-24 86.3 0.0 2.5 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EAQ89989.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EAQ89989.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_4 PF13894.1 EAQ89989.1 - 0.29 11.5 1.8 1.1 9.7 1.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DHHC PF01529.15 EAQ89990.1 - 3.5e-16 59.1 33.3 3.9e-13 49.1 6.8 3.2 2 1 1 3 3 3 2 DHHC palmitoyltransferase DUF1129 PF06570.6 EAQ89990.1 - 0.77 9.0 5.3 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2079 PF09852.4 EAQ89990.1 - 1.1 7.9 7.7 0.029 13.1 0.7 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) Glycos_transf_4 PF00953.16 EAQ89990.1 - 3.7 7.3 10.5 0.12 12.1 1.8 2.1 2 1 0 2 2 2 0 Glycosyl transferase family 4 SET PF00856.23 EAQ89993.1 - 1.1e-19 71.3 1.0 1.1e-19 71.3 0.7 2.9 3 1 0 3 3 3 1 SET domain LSM PF01423.17 EAQ89994.1 - 1e-16 60.1 0.2 1.4e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 EAQ89994.1 - 3.4 8.1 16.8 7.1 7.1 11.6 1.5 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.20 EAQ89995.1 - 0.0066 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ89995.1 - 0.021 13.9 0.1 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UBA_4 PF14555.1 EAQ89996.1 - 2.5e-10 39.7 0.0 5.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EAQ89996.1 - 0.00064 19.7 0.0 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 UBX domain GAT PF03127.9 EAQ89997.1 - 3.7e-16 58.9 0.6 7.4e-16 57.9 0.1 1.7 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EAQ89997.1 - 0.0021 17.6 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain TP2 PF01254.13 EAQ89997.1 - 0.42 10.9 8.0 3.1 8.1 2.3 2.6 2 0 0 2 2 2 0 Nuclear transition protein 2 Zn_clus PF00172.13 EAQ89999.1 - 6.8e-08 32.2 8.4 1.1e-07 31.6 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suf PF05843.9 EAQ89999.1 - 7.4 6.2 10.9 14 5.3 7.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Methyltransf_23 PF13489.1 EAQ90004.1 - 2.4e-16 59.8 0.0 4.3e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ90004.1 - 1.1e-14 54.3 0.0 6e-13 48.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ90004.1 - 3.2e-12 46.7 0.0 8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ90004.1 - 3.8e-12 46.7 0.0 7.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ90004.1 - 7.2e-11 42.4 0.0 1.8e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ90004.1 - 3.1e-10 40.3 0.0 9.7e-10 38.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ90004.1 - 1.5e-07 30.7 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EAQ90004.1 - 5.2e-07 29.7 0.2 1.3e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAQ90004.1 - 0.00038 20.1 0.0 0.0012 18.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EAQ90004.1 - 0.0038 16.3 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EAQ90004.1 - 0.0057 16.0 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain TPMT PF05724.6 EAQ90004.1 - 0.0059 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 EAQ90004.1 - 0.078 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 EAQ90004.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Innate_immun PF12782.2 EAQ90004.1 - 1.1 8.4 8.3 2 7.5 5.7 1.5 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family His_Phos_1 PF00300.17 EAQ90005.1 - 1.1e-22 80.7 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MMTV_SAg PF01054.12 EAQ90006.1 - 0.012 14.5 0.6 0.014 14.2 0.4 1.1 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Golgin_A5 PF09787.4 EAQ90006.1 - 0.018 13.5 7.0 0.023 13.2 4.8 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Pex14_N PF04695.8 EAQ90006.1 - 0.021 14.8 10.1 0.042 13.8 3.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ETRAMP PF09716.5 EAQ90006.1 - 0.22 11.4 1.5 0.26 11.2 0.3 1.6 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NAM-associated PF14303.1 EAQ90006.1 - 0.38 11.0 5.1 0.51 10.6 3.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Med13_C PF06333.7 EAQ90006.1 - 0.83 8.1 3.7 0.91 7.9 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Pneumo_phosprot PF02478.11 EAQ90006.1 - 1.2 8.5 6.3 1.5 8.3 4.3 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein MSA-2c PF12238.3 EAQ90006.1 - 3.9 7.0 8.3 6.2 6.4 5.7 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c MGC-24 PF05283.6 EAQ90006.1 - 5.7 6.6 13.9 9.2 6.0 9.7 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) UCH PF00443.24 EAQ90007.1 - 1.1e-55 188.7 0.0 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ90007.1 - 1.6e-22 80.3 0.0 3.8e-22 79.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EAQ90007.1 - 1e-10 40.8 0.2 2.2e-10 39.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family eIF-3c_N PF05470.7 EAQ90007.1 - 0.099 10.7 8.3 0.022 12.8 3.3 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Paramyxo_ncap PF00973.14 EAQ90007.1 - 0.98 8.0 4.5 1.5 7.4 3.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ARPC4 PF05856.7 EAQ90008.1 - 1.7e-76 255.3 3.9 1.9e-76 255.2 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 EAQ90009.1 - 1.9e-06 27.7 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Minor_tail_Z PF06763.6 EAQ90009.1 - 0.025 14.2 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) Mito_carr PF00153.22 EAQ90010.1 - 6.6e-80 262.9 0.7 1.2e-26 92.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 EAQ90011.1 - 7e-25 87.0 0.0 8.1e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 PX domain PRP21_like_P PF12230.3 EAQ90012.1 - 4.1e-59 199.8 18.8 2.4e-58 197.3 13.1 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EAQ90012.1 - 4.2e-37 125.5 0.7 1.4e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 Surp module Med9 PF07544.8 EAQ90012.1 - 5.4 6.8 8.1 0.1 12.3 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PMT PF02366.13 EAQ90013.1 - 8.7e-73 244.6 18.8 1.5e-72 243.8 13.0 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EAQ90013.1 - 1e-56 191.5 0.0 1.6e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 MIR domain Sec2p PF06428.6 EAQ90015.1 - 1.6e-27 95.3 13.4 1.6e-27 95.3 9.3 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 EAQ90015.1 - 0.099 9.9 22.4 0.15 9.3 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF310 PF03750.8 EAQ90015.1 - 0.78 9.9 4.7 1.6 8.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF4115 PF13464.1 EAQ90016.1 - 0.33 10.6 3.4 7 6.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) SNARE PF05739.14 EAQ90018.1 - 1.7e-18 66.0 5.5 4.9e-18 64.5 0.4 3.0 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EAQ90018.1 - 9.4e-13 48.2 2.6 2.8e-12 46.7 0.0 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EAQ90018.1 - 0.0016 18.0 0.6 0.0053 16.3 0.5 1.8 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ApoLp-III PF07464.6 EAQ90018.1 - 0.015 15.3 2.0 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.7 EAQ90018.1 - 0.065 13.0 0.4 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peripla_BP_2 PF01497.13 EAQ90018.1 - 0.073 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein BLOC1_2 PF10046.4 EAQ90018.1 - 0.15 12.2 2.2 1.2 9.3 0.5 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EAQ90018.1 - 0.15 12.3 2.0 23 5.3 0.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EAQ90018.1 - 0.26 9.9 4.9 0.14 10.7 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Aldo_ket_red PF00248.16 EAQ90019.1 - 4.6e-48 163.4 0.0 5.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EAQ90020.1 - 4.5e-28 97.1 0.7 9.8e-28 96.0 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ90020.1 - 2.5e-18 65.8 0.2 2.5e-18 65.8 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EAQ90020.1 - 0.0097 16.4 0.0 0.028 15.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EAQ90020.1 - 0.037 13.3 0.1 0.064 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EAQ90020.1 - 0.038 13.6 0.3 0.066 12.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EAQ90020.1 - 0.16 11.5 0.1 0.48 9.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EAQ90021.1 - 1.3e-32 113.0 0.5 2.2e-32 112.2 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ90021.1 - 9.3e-24 84.5 0.0 1.3e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ90021.1 - 4.3e-16 59.1 0.6 1.1e-15 57.8 0.4 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ90021.1 - 3e-06 26.8 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAQ90021.1 - 0.0022 17.7 0.4 0.0048 16.6 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EAQ90021.1 - 0.013 14.3 0.1 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EAQ90021.1 - 0.038 13.9 2.0 0.19 11.7 0.7 2.4 2 1 1 3 3 3 0 NADH(P)-binding NmrA PF05368.8 EAQ90021.1 - 0.19 10.9 0.8 1.2 8.3 0.2 2.2 2 1 0 2 2 2 0 NmrA-like family Abhydrolase_6 PF12697.2 EAQ90022.1 - 7.3e-12 45.6 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ90022.1 - 9.4e-12 44.9 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EAQ90022.1 - 1.1e-06 27.5 0.0 1.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EAQ90022.1 - 2.6e-06 26.8 0.0 4.8e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EAQ90022.1 - 5.9e-05 22.6 0.0 8.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EAQ90022.1 - 0.0012 18.3 0.0 0.0048 16.3 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EAQ90022.1 - 0.052 12.7 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.6 EAQ90022.1 - 0.067 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EAQ90022.1 - 0.09 12.0 0.0 1.3 8.2 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.19 EAQ90023.1 - 1.3e-12 47.5 0.0 1.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ90023.1 - 3.7e-09 36.6 0.1 6.4e-09 35.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAQ90023.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAQ90023.1 - 0.034 14.2 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_43 PF04616.9 EAQ90024.1 - 4.9e-29 101.3 6.2 1.8e-27 96.1 4.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EAQ90024.1 - 0.059 12.0 1.4 2.5 6.7 0.0 3.0 2 2 1 3 3 3 0 Levansucrase/Invertase Hyd_WA PF06462.7 EAQ90026.1 - 0.014 15.0 0.2 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 Propeller DUF2052 PF09747.4 EAQ90027.1 - 2.6e-34 118.7 0.6 3.4e-34 118.3 0.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) SSP160 PF06933.6 EAQ90027.1 - 2.4 6.0 7.3 3.1 5.6 5.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EAQ90027.1 - 2.7 7.7 15.7 4.8 6.9 10.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Mito_fiss_reg PF05308.6 EAQ90027.1 - 4.8 6.4 7.5 9.3 5.5 5.2 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator AAA_10 PF12846.2 EAQ90028.1 - 6.9e-08 32.2 0.0 0.00019 21.0 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EAQ90028.1 - 0.00091 18.7 0.0 0.023 14.1 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 EAQ90028.1 - 0.0027 17.5 0.2 0.045 13.5 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EAQ90028.1 - 0.049 12.7 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EAQ90028.1 - 0.082 13.0 0.0 2.6 8.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAQ90028.1 - 0.1 12.5 0.7 0.63 9.9 0.0 2.5 3 1 0 3 3 3 0 AAA ATPase domain RAP1 PF07218.6 EAQ90028.1 - 0.16 10.0 5.4 0.22 9.5 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Telomere_Sde2_2 PF13297.1 EAQ90028.1 - 0.41 9.9 2.2 0.49 9.7 0.1 2.1 2 0 0 2 2 2 0 Telomere stability C-terminal Response_reg PF00072.19 EAQ90029.1 - 2.4e-20 72.6 0.0 1.3e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.3 EAQ90030.1 - 1.2e-56 191.3 3.2 1.2e-56 191.3 2.2 1.6 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.1 EAQ90031.1 - 1.5e-39 135.8 0.0 2.4e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EAQ90031.1 - 7.3e-17 61.2 0.9 1.5e-16 60.2 0.2 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region ABC2_membrane_5 PF13346.1 EAQ90033.1 - 0.018 14.3 3.3 0.025 13.8 2.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MARVEL PF01284.18 EAQ90033.1 - 0.048 13.4 12.0 0.1 12.3 8.3 1.6 1 1 0 1 1 1 0 Membrane-associating domain Polysacc_synt PF01943.12 EAQ90033.1 - 0.24 10.6 4.8 0.45 9.7 3.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein stn_TNFRSF12A PF12191.3 EAQ90033.1 - 0.45 10.5 2.3 0.44 10.5 0.3 1.9 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3592 PF12158.3 EAQ90034.1 - 0.24 11.1 1.7 0.3 10.8 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) SH3_9 PF14604.1 EAQ90036.1 - 1.6e-13 50.0 0.1 3.5e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EAQ90036.1 - 2.2e-13 50.2 0.3 3.1e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EAQ90036.1 - 2.9e-12 45.7 0.3 6.8e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EAQ90036.1 - 1.7e-10 40.2 0.1 3.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dscam_C PF12355.3 EAQ90036.1 - 0.028 14.6 0.9 0.028 14.6 0.6 2.0 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Pex14_N PF04695.8 EAQ90036.1 - 0.083 12.9 1.0 0.21 11.6 0.7 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2439 PF10382.4 EAQ90037.1 - 1.7e-06 28.1 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) zf-C2H2_4 PF13894.1 EAQ90038.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.13 EAQ90040.1 - 0.19 11.6 8.8 0.35 10.8 6.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 EAQ90041.1 - 1.4e-22 79.2 0.0 4.6e-22 77.5 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EAQ90041.1 - 0.015 15.1 1.6 0.098 12.5 0.2 2.4 1 1 0 2 2 2 0 Bd3614-like deaminase APOBEC_N PF08210.6 EAQ90041.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain GFA PF04828.9 EAQ90042.1 - 2.9e-05 23.9 1.2 0.012 15.5 0.5 3.9 4 1 0 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EAQ90042.1 - 0.19 11.5 4.4 6.7 6.6 1.0 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Xan_ur_permease PF00860.15 EAQ90043.1 - 2.5e-25 88.8 27.1 4.6e-23 81.3 17.6 3.0 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.15 EAQ90043.1 - 0.0018 17.3 4.2 0.0029 16.6 1.3 2.3 1 1 1 2 2 2 1 Sulfate transporter family WD40 PF00400.27 EAQ90044.1 - 6.1e-07 29.0 2.7 0.012 15.4 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat eIF2A PF08662.6 EAQ90044.1 - 0.006 16.3 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DRTGG PF07085.7 EAQ90044.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 DRTGG domain Cytochrom_D1 PF02239.11 EAQ90044.1 - 0.05 11.9 0.0 0.088 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 EAQ90044.1 - 0.069 12.8 0.1 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat GRIP PF01465.15 EAQ90045.1 - 1.3e-12 46.9 0.1 2.6e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EAQ90045.1 - 0.00061 19.4 127.8 0.022 14.3 15.1 7.2 3 2 5 8 8 8 3 IncA protein Phage_GP20 PF06810.6 EAQ90045.1 - 0.0013 18.1 8.4 0.0013 18.1 5.8 9.5 3 3 7 10 10 10 2 Phage minor structural protein GP20 DivIC PF04977.10 EAQ90045.1 - 0.01 15.3 1.8 0.01 15.3 1.2 12.6 6 3 6 13 13 13 0 Septum formation initiator CENP-F_leu_zip PF10473.4 EAQ90045.1 - 0.043 13.6 134.6 0.025 14.4 7.8 8.0 3 2 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EAQ90045.1 - 0.068 12.3 127.0 0.3 10.2 15.1 7.9 3 2 4 7 7 7 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EAQ90045.1 - 0.22 10.6 36.8 0.5 9.4 5.3 5.7 3 1 4 7 7 7 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EAQ90045.1 - 1.2 7.4 94.6 0.014 13.9 18.3 4.9 2 1 2 5 5 5 0 AAA domain Lebercilin PF15619.1 EAQ90045.1 - 4.1 6.7 121.6 0.27 10.6 11.3 5.8 4 1 0 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease DUF2296 PF10058.4 EAQ90046.1 - 2.1e-17 62.5 0.1 4.1e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-RanBP PF00641.13 EAQ90046.1 - 0.18 10.9 2.8 0.31 10.1 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF605 PF04652.11 EAQ90046.1 - 0.34 10.2 10.3 0.48 9.7 7.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1399 PF07173.7 EAQ90050.1 - 3.6e-21 75.8 4.5 4.2e-16 59.4 0.4 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) Acetyltransf_7 PF13508.1 EAQ90051.1 - 3.6e-11 43.0 0.0 5.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ90051.1 - 4.2e-09 36.3 0.1 6.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAQ90051.1 - 5.1e-06 26.5 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ90051.1 - 2.1e-05 24.1 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EAQ90051.1 - 0.016 15.0 0.1 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAQ90051.1 - 0.061 13.4 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bac_rhamnosid PF05592.6 EAQ90053.1 - 6.5e-30 103.8 0.0 2.3e-26 92.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Zn_clus PF00172.13 EAQ90054.1 - 1.8e-08 34.1 15.5 8.1e-08 32.0 11.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EAQ90055.1 - 5e-55 186.4 16.6 8.3e-55 185.7 11.5 1.3 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 EAQ90055.1 - 0.0049 16.5 1.2 0.0081 15.8 0.0 1.9 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Caveolin PF01146.12 EAQ90055.1 - 1.4 8.5 7.1 0.065 12.8 0.5 2.0 2 0 0 2 2 2 0 Caveolin Kelch_5 PF13854.1 EAQ90056.1 - 5.8e-12 45.2 2.6 8.2e-09 35.2 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EAQ90056.1 - 8e-08 31.9 8.5 0.049 13.4 0.1 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EAQ90056.1 - 0.00022 21.3 8.2 0.004 17.2 0.1 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Podoplanin PF05808.6 EAQ90056.1 - 0.0021 17.6 1.9 0.0043 16.6 1.3 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 EAQ90056.1 - 0.05 12.2 0.7 0.073 11.6 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MGC-24 PF05283.6 EAQ90056.1 - 0.053 13.3 1.6 0.1 12.3 1.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Syndecan PF01034.15 EAQ90056.1 - 0.23 11.1 0.2 0.44 10.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain HLH PF00010.21 EAQ90058.1 - 2.3e-16 59.2 0.4 4.1e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 EAQ90058.1 - 0.00083 19.6 1.9 0.018 15.3 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EAQ90058.1 - 0.013 15.4 0.7 0.013 15.4 0.5 1.9 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EAQ90058.1 - 0.12 12.1 0.3 0.12 12.1 0.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DOMON PF03351.12 EAQ90061.1 - 0.059 13.2 1.2 0.077 12.9 0.1 1.7 2 0 0 2 2 2 0 DOMON domain DUF4091 PF13320.1 EAQ90062.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Romo1 PF10247.4 EAQ90063.1 - 0.048 13.8 1.0 0.12 12.6 0.7 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 BCS1_N PF08740.6 EAQ90064.1 - 1.2e-36 126.0 0.9 1.7e-36 125.5 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EAQ90064.1 - 2.1e-06 27.9 0.2 3.4e-05 24.0 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAQ90064.1 - 6.4e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ90064.1 - 0.00019 22.2 0.0 0.00051 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EAQ90064.1 - 0.011 15.3 0.2 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ90064.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PPV_E1_C PF00519.12 EAQ90064.1 - 0.031 12.8 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase KaiC PF06745.8 EAQ90064.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EAQ90064.1 - 0.041 13.6 0.1 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAQ90064.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAQ90064.1 - 0.085 13.0 0.1 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EAQ90064.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EAQ90064.1 - 0.2 10.3 0.0 0.41 9.2 0.0 1.4 2 0 0 2 2 2 0 TIP49 C-terminus IncA PF04156.9 EAQ90065.1 - 0.0032 17.0 2.9 0.0052 16.4 2.0 1.3 1 0 0 1 1 1 1 IncA protein Lge1 PF11488.3 EAQ90065.1 - 0.049 13.8 0.2 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 TMF_DNA_bd PF12329.3 EAQ90065.1 - 0.08 12.7 0.6 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 EAQ90065.1 - 0.12 12.1 1.6 0.17 11.6 0.4 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Herpes_UL6 PF01763.11 EAQ90065.1 - 0.13 10.4 0.7 0.18 9.9 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like SlyX PF04102.7 EAQ90065.1 - 0.16 12.3 8.7 3.8 7.9 2.6 2.5 1 1 1 2 2 2 0 SlyX APG6 PF04111.7 EAQ90065.1 - 0.32 10.0 1.4 0.45 9.4 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EAQ90065.1 - 0.35 10.3 4.7 1.3 8.5 0.6 2.2 1 1 1 2 2 2 0 Septum formation initiator XYPPX PF02162.12 EAQ90067.1 - 0.00065 19.2 76.8 0.058 12.9 19.5 4.8 2 1 2 4 4 4 3 XYPPX repeat (two copies) Pro-rich PF15240.1 EAQ90067.1 - 0.041 13.9 18.2 0.042 13.9 12.6 1.1 1 0 0 1 1 1 0 Proline-rich GST_N_3 PF13417.1 EAQ90069.1 - 5.7e-17 61.7 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ90069.1 - 8.1e-14 51.3 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAQ90069.1 - 4.4e-12 46.0 0.0 7.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EAQ90069.1 - 6e-06 26.1 0.0 1.7e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.1 EAQ90069.1 - 0.0052 16.6 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ90069.1 - 0.021 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex16 PF08610.5 EAQ90070.1 - 7.5e-102 340.7 0.0 8.9e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) GMC_oxred_N PF00732.14 EAQ90071.1 - 1.5e-77 260.6 0.0 2.1e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ90071.1 - 6.1e-37 127.0 0.0 1.2e-36 126.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ90071.1 - 1.7e-05 23.8 0.9 0.0086 15.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAQ90071.1 - 0.0012 17.7 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAQ90071.1 - 0.0015 17.4 0.2 0.79 8.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EAQ90071.1 - 0.013 14.5 0.1 0.05 12.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EAQ90071.1 - 0.054 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_2 PF07716.10 EAQ90072.1 - 6e-08 32.3 14.3 1.3e-07 31.3 9.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EAQ90072.1 - 0.00013 21.8 11.0 0.00028 20.7 7.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EAQ90072.1 - 0.016 15.4 11.1 0.033 14.4 7.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF427 PF04248.7 EAQ90074.1 - 1.6e-08 34.0 0.0 9.7e-08 31.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF427) Snf7 PF03357.16 EAQ90075.1 - 1.1e-06 28.1 26.4 1.7e-06 27.5 18.3 1.3 1 0 0 1 1 1 1 Snf7 FANCI_S1 PF14675.1 EAQ90075.1 - 0.014 14.7 0.7 0.38 10.0 0.0 2.2 2 1 0 2 2 2 0 FANCI solenoid 1 3-dmu-9_3-mt PF06983.8 EAQ90075.1 - 0.23 11.8 1.8 0.26 11.6 0.2 1.7 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase XLF PF09302.6 EAQ90075.1 - 0.36 10.5 6.3 0.13 12.0 0.6 2.6 1 1 1 2 2 2 0 XLF (XRCC4-like factor) Vfa1 PF08432.5 EAQ90075.1 - 2.3 8.1 14.7 4.4 7.3 10.1 1.5 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SOBP PF15279.1 EAQ90075.1 - 5.7 7.2 7.1 6.7 6.9 4.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Spore_II_R PF09551.5 EAQ90075.1 - 6.8 6.7 7.9 5.8 6.9 4.1 1.8 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Bud13 PF09736.4 EAQ90075.1 - 9.4 6.4 18.6 26 5.0 1.5 2.1 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex DSHCT PF08148.7 EAQ90076.1 - 6.9e-61 204.6 0.6 1.3e-60 203.6 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EAQ90076.1 - 8e-21 74.2 0.0 2.1e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ90076.1 - 1.2e-06 28.2 0.6 4.3e-06 26.4 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EAQ90076.1 - 0.00039 19.6 0.0 0.004 16.3 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain ResIII PF04851.10 EAQ90076.1 - 0.0088 15.8 0.1 0.18 11.5 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EAQ90076.1 - 0.045 13.7 0.1 5.4 6.9 0.1 2.9 2 0 0 2 2 2 0 AAA ATPase domain dUTPase PF00692.14 EAQ90077.1 - 4.1e-13 48.9 0.0 5.2e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase adh_short PF00106.20 EAQ90078.1 - 4.7e-27 94.9 1.7 6.8e-27 94.4 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ90078.1 - 4.4e-18 65.9 0.0 5.4e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ90078.1 - 6.5e-10 38.9 1.2 1.1e-09 38.2 0.8 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EAQ90078.1 - 1.6e-05 24.6 0.1 2.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EAQ90078.1 - 0.0053 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EAQ90078.1 - 0.0056 16.1 0.1 0.0082 15.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EAQ90078.1 - 0.012 14.7 0.1 0.032 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 EAQ90078.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EAQ90078.1 - 0.028 14.9 0.1 0.1 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ90078.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.18 EAQ90078.1 - 0.11 12.3 0.1 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EAQ90078.1 - 0.12 12.1 1.8 0.78 9.5 0.4 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ICL PF00463.16 EAQ90079.1 - 3.1e-194 646.0 0.2 3.6e-194 645.8 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EAQ90079.1 - 8.2e-13 48.1 0.2 1.2e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Swi3 PF07962.7 EAQ90080.1 - 1.1e-29 101.9 0.4 3.6e-29 100.2 0.2 2.0 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 DUF3246 PF11596.3 EAQ90080.1 - 6.5 5.9 18.6 0.63 9.2 1.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) EcKinase PF02958.15 EAQ90081.1 - 0.0034 16.5 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EAQ90081.1 - 0.0079 15.9 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gp37 PF09646.5 EAQ90081.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Gp37 protein NADH-u_ox-rdase PF10785.4 EAQ90082.1 - 1e-34 118.6 0.6 1.7e-34 117.9 0.4 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EAQ90082.1 - 7.7e-33 112.0 0.0 1.4e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Glyco_hydro_61 PF03443.9 EAQ90083.1 - 3.4e-50 170.8 0.1 1.1e-49 169.1 0.1 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ90083.1 - 3.3e-10 39.4 12.8 3.3e-10 39.4 8.8 3.1 2 2 0 2 2 2 1 Fungal cellulose binding domain SGL PF08450.7 EAQ90084.1 - 5.8e-19 68.4 0.0 1.1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EAQ90084.1 - 0.00011 22.1 0.0 0.0015 18.5 0.0 2.6 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EAQ90084.1 - 0.057 13.4 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Arylesterase SWIRM PF04433.12 EAQ90087.1 - 1.9e-16 59.9 0.0 3.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain adh_short PF00106.20 EAQ90088.1 - 6.4e-22 78.2 2.5 4.5e-21 75.4 1.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ90088.1 - 1.1e-19 71.2 0.1 1.5e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ90088.1 - 5e-10 39.3 1.5 3.2e-09 36.7 0.1 2.1 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EAQ90088.1 - 5.2e-06 26.6 0.1 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EAQ90088.1 - 0.00013 22.0 1.1 0.0015 18.5 0.2 2.5 2 1 0 2 2 2 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 EAQ90088.1 - 0.00024 20.5 0.3 0.0059 16.0 0.0 2.4 2 1 1 3 3 3 1 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.16 EAQ90088.1 - 0.00099 18.6 0.4 0.0016 17.8 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ90088.1 - 0.0012 17.7 0.3 0.0028 16.6 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EAQ90088.1 - 0.003 17.2 0.3 0.019 14.6 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ90088.1 - 0.01 16.2 0.8 0.067 13.6 0.2 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EAQ90088.1 - 0.013 15.7 0.4 0.039 14.2 0.2 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.14 EAQ90088.1 - 0.02 13.6 0.2 0.03 13.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EAQ90088.1 - 0.022 13.7 0.7 0.028 13.3 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EAQ90088.1 - 0.025 14.1 0.1 0.049 13.1 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AA_kinase PF00696.23 EAQ90088.1 - 0.034 13.7 0.1 0.099 12.1 0.0 1.6 1 1 0 2 2 2 0 Amino acid kinase family ApbA PF02558.11 EAQ90088.1 - 0.052 12.9 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EAQ90088.1 - 0.081 13.3 0.6 0.2 12.0 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 EAQ90088.1 - 0.25 10.5 1.5 0.66 9.1 0.2 2.0 2 0 0 2 2 2 0 NmrA-like family Grp1_Fun34_YaaH PF01184.14 EAQ90089.1 - 3.6e-10 39.4 13.1 1.9e-05 24.1 6.2 2.7 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family DUF3096 PF11295.3 EAQ90089.1 - 0.87 9.1 3.9 0.25 10.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) QCR10 PF09796.4 EAQ90089.1 - 3.3 7.4 10.7 9.4 5.9 1.6 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4212 PF13937.1 EAQ90089.1 - 7.9 6.5 10.0 4.9 7.2 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) DUF1691 PF07950.6 EAQ90090.1 - 1.3e-13 50.8 0.1 2.1e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.3 EAQ90091.1 - 1.2e-06 28.4 4.4 1.9e-06 27.8 3.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ90091.1 - 0.00013 22.0 0.8 0.00021 21.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EAQ90091.1 - 0.0058 16.8 0.2 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EAQ90091.1 - 0.017 15.2 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EAQ90091.1 - 0.034 14.4 1.0 0.059 13.7 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF965 PF06135.7 EAQ90091.1 - 0.093 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) Fungal_trans PF04082.13 EAQ90092.1 - 0.0001 21.2 0.0 0.00046 19.1 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ90092.1 - 0.00071 19.4 4.1 0.0022 17.8 2.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4580 PF15162.1 EAQ90092.1 - 0.12 11.6 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) Cu_amine_oxid PF01179.15 EAQ90093.1 - 2.2e-158 527.3 0.0 2.9e-158 526.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EAQ90093.1 - 1.1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EAQ90093.1 - 4.6e-08 33.0 0.0 9.4e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Epimerase PF01370.16 EAQ90094.1 - 2.5e-19 69.6 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ90094.1 - 3.5e-08 32.4 0.0 4.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAQ90094.1 - 2.5e-06 26.6 0.1 7.9e-06 24.9 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EAQ90094.1 - 0.00053 20.0 0.2 0.0075 16.2 0.1 2.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EAQ90094.1 - 0.0062 16.4 1.4 0.024 14.5 1.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EAQ90094.1 - 0.089 12.0 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Lipase_GDSL_2 PF13472.1 EAQ90095.1 - 1.1e-09 38.6 0.1 1.7e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ90095.1 - 3.5e-09 36.8 0.8 1.4e-08 34.9 0.5 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TRAM_LAG1_CLN8 PF03798.11 EAQ90096.1 - 4.6e-45 153.6 14.0 6.9e-45 153.0 9.7 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EAQ90096.1 - 3.2e-19 68.1 0.0 6.9e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein RRM_1 PF00076.17 EAQ90097.1 - 4.5e-15 55.0 0.0 4.8e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ90097.1 - 3.9e-10 39.5 0.0 8.9e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ90097.1 - 2.3e-05 24.1 0.0 7.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTV_NS2 PF04514.7 EAQ90097.1 - 1.9 7.3 15.5 2.5 6.8 10.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 LCD1 PF09798.4 EAQ90097.1 - 3.9 5.3 5.8 4.4 5.1 4.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein WD40 PF00400.27 EAQ90098.1 - 1.5e-11 43.6 1.8 0.00019 21.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 EAQ90098.1 - 0.00015 21.0 0.1 0.0067 15.5 0.0 2.5 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Apc4_WD40 PF12894.2 EAQ90098.1 - 0.04 13.4 0.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EAQ90098.1 - 0.079 10.7 0.0 0.46 8.2 0.0 2.1 2 1 1 3 3 3 0 IKI3 family BBE PF08031.7 EAQ90098.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Berberine and berberine like Septin PF00735.13 EAQ90099.1 - 2.3e-106 354.9 0.0 5.2e-106 353.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EAQ90099.1 - 0.00035 20.5 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAQ90099.1 - 0.0026 17.6 4.0 1.1 9.0 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 EAQ90099.1 - 0.0041 17.9 1.1 0.087 13.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ90099.1 - 0.0061 15.7 0.2 0.021 14.0 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EAQ90099.1 - 0.026 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EAQ90099.1 - 0.04 12.7 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.1 EAQ90099.1 - 0.06 13.2 0.6 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EAQ90099.1 - 0.074 13.1 0.1 0.26 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EAQ90099.1 - 0.094 13.2 0.3 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EAQ90099.1 - 0.097 12.1 0.1 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EAQ90099.1 - 0.28 10.6 0.1 0.28 10.6 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family V_ATPase_I PF01496.14 EAQ90099.1 - 1.4 6.6 2.8 2.1 6.1 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3653 PF12375.3 EAQ90099.1 - 8.9 6.6 10.2 4.1 7.6 0.3 3.3 2 1 1 3 3 3 0 Phage protein Bax1-I PF01027.15 EAQ90100.1 - 7.2e-51 172.7 27.8 8.4e-51 172.4 19.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 EAQ90100.1 - 0.045 12.7 3.6 0.077 11.9 0.3 2.2 2 0 0 2 2 2 0 Orbivirus NS3 Spore_YhaL PF14147.1 EAQ90100.1 - 0.1 12.0 0.0 0.33 10.4 0.0 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL DUF308 PF03729.8 EAQ90100.1 - 0.46 10.5 17.6 0.24 11.3 1.6 3.6 1 1 3 4 4 4 0 Short repeat of unknown function (DUF308) DUF4407 PF14362.1 EAQ90100.1 - 8.6 5.2 15.5 0.18 10.7 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DLIC PF05783.6 EAQ90101.1 - 4.4e-34 117.9 0.1 1.3e-32 113.1 0.0 2.4 3 0 0 3 3 3 1 Dynein light intermediate chain (DLIC) Phage_tail_2 PF06199.6 EAQ90101.1 - 0.021 14.8 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Phage major tail protein 2 Thioredox_DsbH PF03190.10 EAQ90102.1 - 6.6e-59 198.2 0.0 1.2e-58 197.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EAQ90102.1 - 0.00011 22.1 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like DUF4360 PF14273.1 EAQ90104.1 - 1.8e-73 246.1 4.4 2.1e-73 245.9 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) hGDE_N PF14699.1 EAQ90104.1 - 0.0088 15.8 0.2 0.018 14.8 0.2 1.6 1 1 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Citrate_synt PF00285.16 EAQ90105.1 - 3e-85 286.0 0.0 9.7e-77 258.0 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase Gln-synt_C PF00120.19 EAQ90106.1 - 1.2e-65 221.2 0.0 1.6e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain AMP-binding PF00501.23 EAQ90108.1 - 3.6e-67 226.5 0.3 9.7e-66 221.8 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ90108.1 - 8.8e-12 45.8 0.0 3.4e-11 43.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 EAQ90110.1 - 1.8e-17 63.9 7.1 2.9e-17 63.3 4.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ90110.1 - 4.2e-10 39.5 2.6 6.2e-10 38.9 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ90110.1 - 0.00045 19.8 2.9 0.00045 19.8 2.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4215 PF13948.1 EAQ90111.1 - 3.1e-29 100.9 184.3 0.0074 16.4 5.3 15.2 2 1 13 15 15 15 14 Domain of unknown function (DUF4215) WD40 PF00400.27 EAQ90112.1 - 2.7e-18 65.0 0.3 8.3e-05 22.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3107 PF11305.3 EAQ90112.1 - 0.038 13.8 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) GDC-P PF02347.11 EAQ90113.1 - 2.6e-159 530.5 0.0 4.9e-155 516.4 0.0 2.3 2 1 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 EAQ90113.1 - 0.042 12.1 0.0 0.075 11.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Tom5 PF10642.4 EAQ90114.1 - 8.1e-21 73.4 0.9 8.7e-21 73.3 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EAQ90115.1 - 1.6e-44 150.9 0.0 1.6e-44 150.9 0.0 2.8 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Peptidase_C58 PF03543.9 EAQ90115.1 - 0.00072 19.0 4.8 0.0071 15.8 1.7 2.4 2 0 0 2 2 2 1 Yersinia/Haemophilus virulence surface antigen Iso_dh PF00180.15 EAQ90115.1 - 0.14 11.0 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Spt20 PF12090.3 EAQ90115.1 - 0.19 11.0 9.4 0.37 10.1 6.5 1.4 1 0 0 1 1 1 0 Spt20 family Adeno_hexon PF01065.14 EAQ90115.1 - 0.22 10.3 5.5 0.3 9.8 3.8 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Pex14_N PF04695.8 EAQ90115.1 - 0.42 10.6 12.8 0.87 9.6 8.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 EAQ90115.1 - 1.1 8.9 13.9 0.57 9.8 8.0 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) YtxH PF12732.2 EAQ90115.1 - 1.2 9.5 5.1 0.69 10.3 0.3 2.5 3 0 0 3 3 2 0 YtxH-like protein FimP PF09766.4 EAQ90115.1 - 1.3 8.0 18.0 0.23 10.4 9.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein DUF4407 PF14362.1 EAQ90115.1 - 1.5 7.7 12.8 1.1 8.2 3.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Utp8 PF10395.4 EAQ90115.1 - 1.7 6.8 5.9 6.1 5.0 0.1 2.1 2 0 0 2 2 2 0 Utp8 family Med15 PF09606.5 EAQ90115.1 - 3.5 5.7 33.3 5.3 5.1 23.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 EAQ90115.1 - 5.1 5.6 4.8 7.4 5.1 3.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FliX PF10768.4 EAQ90115.1 - 9.1 6.5 10.1 0.98 9.6 0.5 2.4 2 0 0 2 2 2 0 Class II flagellar assembly regulator CHCH PF06747.8 EAQ90116.1 - 2e-08 33.9 17.4 1.3e-07 31.3 4.7 2.7 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EAQ90116.1 - 0.0004 20.1 12.3 0.019 14.7 0.7 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EAQ90116.1 - 0.078 13.0 9.1 0.48 10.5 5.8 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Gemini_AL1_M PF08283.6 EAQ90116.1 - 0.1 12.4 1.6 0.19 11.6 0.7 1.7 1 1 1 2 2 2 0 Geminivirus rep protein central domain CAP PF00188.21 EAQ90118.1 - 3.3e-18 66.3 2.3 4.6e-18 65.8 1.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family COesterase PF00135.23 EAQ90119.1 - 8.1e-61 206.3 0.0 1.1e-60 205.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ90119.1 - 7.3e-09 35.5 0.2 1.6e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAQ90119.1 - 0.00066 18.4 0.0 0.044 12.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAQ90119.1 - 0.037 13.7 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UbiD PF01977.11 EAQ90119.1 - 0.22 9.9 0.1 0.33 9.3 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UvrD_C_2 PF13538.1 EAQ90120.1 - 0.00077 19.5 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EAQ90120.1 - 0.17 10.7 0.1 0.32 9.9 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Glyco_hydro_16 PF00722.16 EAQ90121.1 - 8.6e-20 70.7 0.1 7e-19 67.8 0.1 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 EAQ90121.1 - 0.03 12.5 0.0 0.043 12.0 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Bacteriocin_IId PF09221.5 EAQ90121.1 - 0.16 11.9 0.1 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like Glyco_trans_2_3 PF13632.1 EAQ90122.1 - 1.6e-46 158.4 5.2 1.6e-46 158.4 3.6 2.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAQ90122.1 - 8.9e-07 28.9 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAQ90122.1 - 1.5e-05 24.7 0.0 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAQ90122.1 - 0.038 13.2 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Ank_2 PF12796.2 EAQ90123.1 - 4.5e-51 171.1 17.2 5.2e-19 68.3 0.4 2.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) HET PF06985.6 EAQ90123.1 - 1.8e-42 144.7 0.4 3.2e-42 143.9 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 EAQ90123.1 - 4.2e-20 70.4 9.3 0.00016 21.3 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EAQ90123.1 - 2.3e-14 52.0 1.9 0.016 15.3 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EAQ90123.1 - 2.2e-13 50.2 0.7 0.00047 20.5 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ90123.1 - 5.4e-09 36.0 3.0 0.0028 17.8 0.1 4.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Mur_ligase PF01225.20 EAQ90123.1 - 0.0086 16.1 3.0 2.1 8.4 0.7 3.3 1 1 1 2 2 2 2 Mur ligase family, catalytic domain ABC_tran PF00005.22 EAQ90124.1 - 6.2e-49 165.8 0.0 2.5e-26 92.6 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAQ90124.1 - 5.9e-16 59.2 4.8 7.8e-06 26.0 0.3 3.8 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EAQ90124.1 - 1.2e-12 47.5 0.4 0.0015 17.8 0.0 4.5 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAQ90124.1 - 4.4e-08 33.6 1.5 0.00067 20.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EAQ90124.1 - 1.4e-07 30.9 0.6 0.0088 15.5 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EAQ90124.1 - 7.6e-07 29.9 0.0 0.014 16.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EAQ90124.1 - 1.5e-06 28.1 0.0 0.011 15.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Chromo PF00385.19 EAQ90124.1 - 1.9e-06 27.4 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 EAQ90124.1 - 3.6e-06 26.7 0.0 0.1 12.5 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EAQ90124.1 - 3.7e-06 26.2 0.0 0.016 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EAQ90124.1 - 3.8e-06 26.2 0.0 0.09 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EAQ90124.1 - 1.4e-05 25.1 0.6 0.19 11.8 0.1 3.4 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 EAQ90124.1 - 4.6e-05 23.8 0.0 0.076 13.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EAQ90124.1 - 8.1e-05 22.1 1.4 0.39 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 EAQ90124.1 - 0.0002 21.2 0.0 0.77 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EAQ90124.1 - 0.00027 20.8 0.7 0.34 10.7 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function DUF87 MobB PF03205.9 EAQ90124.1 - 0.00071 19.2 0.1 0.39 10.4 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EAQ90124.1 - 0.00094 19.1 0.0 0.041 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAQ90124.1 - 0.0012 18.3 0.0 2.3 7.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EAQ90124.1 - 0.0013 18.4 0.3 0.81 9.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EAQ90124.1 - 0.0015 18.7 0.1 3.2 7.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 EAQ90124.1 - 0.002 16.9 0.2 0.46 9.2 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_13 PF13166.1 EAQ90124.1 - 0.0022 16.5 0.1 0.79 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAQ90124.1 - 0.0022 18.3 0.1 0.28 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EAQ90124.1 - 0.0035 17.1 0.0 0.25 11.1 0.0 3.1 2 1 0 2 2 2 1 Dynamin family AAA PF00004.24 EAQ90124.1 - 0.0092 16.1 0.0 4.8 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EAQ90124.1 - 0.012 15.1 0.1 6.7 6.2 0.0 3.1 4 0 0 4 4 2 0 AAA domain HEAT_2 PF13646.1 EAQ90124.1 - 0.022 15.0 1.4 1.7 8.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeats PduV-EutP PF10662.4 EAQ90124.1 - 0.024 14.1 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EAQ90124.1 - 0.025 14.4 0.0 3.9 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EAQ90124.1 - 0.034 11.4 1.4 2.7 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT PF02985.17 EAQ90124.1 - 0.06 13.4 0.4 47 4.4 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat MutS_V PF00488.16 EAQ90124.1 - 0.062 12.6 0.1 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 MutS domain V Arch_ATPase PF01637.13 EAQ90124.1 - 0.088 12.4 0.4 10 5.7 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_16 PF13191.1 EAQ90124.1 - 0.22 11.5 3.5 2.3 8.1 0.1 3.3 3 1 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.10 EAQ90124.1 - 0.34 10.5 1.9 16 5.1 0.1 3.0 3 0 0 3 3 2 0 NTPase Fibrinogen_aC PF12160.3 EAQ90125.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha C domain RRM_1 PF00076.17 EAQ90126.1 - 2.5e-15 55.8 0.0 3.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ90126.1 - 4.9e-14 52.0 0.0 7.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ90126.1 - 1.9e-07 30.7 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pectate_lyase_3 PF12708.2 EAQ90130.1 - 1.8e-65 221.2 9.3 2.6e-54 184.7 1.9 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein Rpp20 PF12328.3 EAQ90132.1 - 8.7e-23 80.5 0.0 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EAQ90132.1 - 2e-18 65.7 0.0 2.7e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Alba Chorion_3 PF05387.6 EAQ90132.1 - 0.025 14.0 0.3 0.038 13.4 0.2 1.3 1 0 0 1 1 1 0 Chorion family 3 Rogdi_lz PF10259.4 EAQ90133.1 - 1.8e-95 319.1 0.0 2.1e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NIPSNAP PF07978.8 EAQ90134.1 - 9.3e-36 121.8 0.5 3.6e-28 97.5 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.4 EAQ90134.1 - 0.052 13.0 7.6 0.079 12.4 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF566 PF04484.7 EAQ90134.1 - 0.46 9.9 8.5 0.64 9.4 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) ATP-synt_J PF04911.7 EAQ90135.1 - 1.9e-08 33.6 10.0 3.4e-05 23.2 6.9 2.1 1 1 0 1 1 1 1 ATP synthase j chain FSH1 PF03959.8 EAQ90136.1 - 3.7e-12 46.1 0.0 4.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Clr5 PF14420.1 EAQ90138.1 - 5.1e-20 71.1 4.1 7.7e-20 70.5 2.9 1.3 1 0 0 1 1 1 1 Clr5 domain Sugar_tr PF00083.19 EAQ90139.1 - 1.6e-75 254.4 26.4 2e-75 254.1 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ90139.1 - 1.1e-15 57.2 31.4 1.1e-15 57.2 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_2 PF13391.1 EAQ90141.1 - 4.4e-12 45.5 0.5 4.4e-12 45.5 0.4 1.9 2 0 0 2 2 2 1 HNH endonuclease Methyltransf_11 PF08241.7 EAQ90142.1 - 1.2e-16 60.9 0.0 2.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ90142.1 - 1.2e-14 54.3 0.0 2.2e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ90142.1 - 1.2e-13 50.9 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ90142.1 - 3.7e-12 46.8 0.0 7.5e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ90142.1 - 3.7e-09 36.6 0.3 6e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ90142.1 - 8.1e-09 35.8 0.1 1.6e-08 34.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 EAQ90142.1 - 3.2e-08 32.9 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EAQ90142.1 - 4.9e-07 30.0 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ90142.1 - 1.2e-05 24.5 0.0 0.00054 19.1 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EAQ90142.1 - 2.9e-05 23.5 0.0 4.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EAQ90142.1 - 0.00013 21.2 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EAQ90142.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EAQ90142.1 - 0.0038 16.8 0.0 0.0044 16.6 0.0 1.2 1 1 0 1 1 1 1 Met-10+ like-protein NodS PF05401.6 EAQ90142.1 - 0.0071 15.7 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 EAQ90142.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 EAQ90142.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 EAQ90142.1 - 0.044 13.1 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FmrO PF07091.6 EAQ90142.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 EAQ90142.1 - 0.095 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EAQ90142.1 - 0.099 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EAQ90142.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 G-alpha PF00503.15 EAQ90143.1 - 0.00014 20.7 0.2 0.00033 19.4 0.1 1.5 1 1 1 2 2 2 1 G-protein alpha subunit Pox_A32 PF04665.7 EAQ90143.1 - 0.0033 16.7 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein MCM PF00493.18 EAQ90143.1 - 0.048 12.4 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family Arf PF00025.16 EAQ90143.1 - 0.099 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family p450 PF00067.17 EAQ90145.1 - 3.6e-44 151.0 0.0 5.2e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EAQ90146.1 - 3.7e-38 130.6 1.8 6e-38 129.9 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Myb_DNA-bind_6 PF13921.1 EAQ90147.1 - 0.00039 20.4 1.0 0.0012 18.8 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ90147.1 - 0.0014 18.6 0.2 0.0047 16.9 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_Tnp_1 PF01527.15 EAQ90147.1 - 0.029 14.3 0.4 0.16 11.9 0.1 2.2 1 1 1 2 2 2 0 Transposase HTH_32 PF13565.1 EAQ90147.1 - 6.8 7.5 7.0 2.2 9.1 0.9 3.0 3 0 0 3 3 3 0 Homeodomain-like domain APH PF01636.18 EAQ90148.1 - 2.6e-19 69.9 0.1 1.2e-18 67.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family YjeF_N PF03853.10 EAQ90152.1 - 2.6e-14 53.1 0.1 2.9e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EAQ90153.1 - 4.9e-25 87.0 0.0 7.7e-25 86.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 EAQ90154.1 - 1.7e-81 273.7 6.2 2.5e-81 273.2 4.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 EAQ90155.1 - 6.5e-18 64.5 45.5 2.9e-17 62.4 29.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ90155.1 - 1.1e-06 27.1 21.0 1.6e-06 26.6 14.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) W_rich_C PF07483.6 EAQ90155.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain Reprolysin_2 PF13574.1 EAQ90156.1 - 0.0062 16.6 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAQ90156.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAQ90156.1 - 0.024 14.5 0.1 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Trypan_PARP PF05887.6 EAQ90156.1 - 0.059 13.1 0.1 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4404 PF14357.1 EAQ90157.1 - 0.18 12.2 1.5 0.69 10.3 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) SH3_1 PF00018.23 EAQ90159.1 - 3.1e-09 36.0 0.1 4.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ90159.1 - 5.6e-07 28.9 0.0 9.6e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAQ90159.1 - 1e-06 28.2 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.6 EAQ90160.1 - 1.7e-39 134.9 0.0 2.5e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Spc19 Med3 PF11593.3 EAQ90161.1 - 0.41 9.8 6.7 0.62 9.2 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ABC2_membrane PF01061.19 EAQ90162.1 - 2.2e-92 307.9 56.8 3.4e-48 163.6 11.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EAQ90162.1 - 2.4e-31 107.4 0.0 9.1e-25 86.3 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EAQ90162.1 - 4.8e-28 98.1 0.1 1.6e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAQ90162.1 - 0.00026 21.0 0.1 0.68 9.8 0.0 2.8 2 1 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EAQ90162.1 - 0.00059 18.9 41.4 0.0021 17.1 11.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 EAQ90162.1 - 0.00069 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EAQ90162.1 - 0.00077 18.9 0.1 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EAQ90162.1 - 0.0011 18.8 0.0 0.0081 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ90162.1 - 0.0017 18.3 0.5 0.033 14.1 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EAQ90162.1 - 0.002 18.0 0.1 0.0048 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ90162.1 - 0.0022 18.3 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ90162.1 - 0.0057 17.4 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAQ90162.1 - 0.029 13.7 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EAQ90162.1 - 0.033 13.4 0.0 0.31 10.2 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAQ90162.1 - 0.041 13.3 0.2 0.14 11.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EAQ90162.1 - 0.051 13.5 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EAQ90162.1 - 0.072 13.2 0.0 0.3 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EAQ90162.1 - 0.097 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EAQ90162.1 - 0.13 11.7 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EAQ90162.1 - 0.14 11.6 0.2 0.29 10.5 0.2 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EAQ90162.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin Cupin_2 PF07883.6 EAQ90163.1 - 6e-10 38.4 0.3 1.5e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EAQ90163.1 - 0.06 12.7 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF605 PF04652.11 EAQ90163.1 - 6.1 6.1 11.3 7.3 5.8 7.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF2360 PF10152.4 EAQ90163.1 - 9.6 6.4 10.2 13 6.0 7.1 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Toxin_3 PF00537.13 EAQ90164.1 - 1.9 8.4 7.0 4.7 7.1 4.7 1.9 1 1 0 1 1 1 0 Scorpion toxin-like domain CorA PF01544.13 EAQ90165.1 - 3.9e-05 22.8 1.0 0.00013 21.1 0.7 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-RNPHF PF08080.7 EAQ90165.1 - 0.044 13.2 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 RNPHF zinc finger MULE PF10551.4 EAQ90166.1 - 4.1e-21 74.9 0.1 1.3e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ90166.1 - 2.5e-07 29.6 1.1 2.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Transposase, Mutator family AIG1 PF04548.11 EAQ90166.1 - 1.6e-06 27.3 0.1 5.8e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 EAQ90166.1 - 1.1e-05 25.3 0.0 3.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAQ90166.1 - 0.00098 18.9 0.9 0.97 9.2 0.0 3.0 2 1 1 3 3 3 2 Dynamin family FAR1 PF03101.10 EAQ90166.1 - 0.0045 17.4 0.3 0.016 15.7 0.2 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain Cellulase PF00150.13 EAQ90166.1 - 0.037 13.2 0.8 4 6.5 0.2 2.3 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AAA_17 PF13207.1 EAQ90166.1 - 0.064 14.0 0.0 0.67 10.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ90166.1 - 0.13 11.7 0.1 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_4 PF08386.5 EAQ90167.1 - 8.4e-17 60.9 0.0 2.1e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ90167.1 - 2e-12 47.1 0.0 3.4e-05 23.5 0.0 3.4 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ90167.1 - 2.5e-06 27.5 0.9 7.7e-05 22.6 0.6 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 EAQ90169.1 - 1.7e-18 66.7 0.0 2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ90169.1 - 1.2e-07 31.1 0.0 1.7e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ90169.1 - 3e-05 23.8 0.0 0.00083 19.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAQ90169.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AMP-binding PF00501.23 EAQ90170.1 - 0 1202.4 5.9 1.3e-85 287.3 0.1 6.5 5 1 1 6 6 6 5 AMP-binding enzyme Condensation PF00668.15 EAQ90170.1 - 0 1215.9 0.0 6.7e-55 186.0 0.0 12.1 10 2 0 11 11 11 10 Condensation domain PP-binding PF00550.20 EAQ90170.1 - 1.6e-68 226.8 0.1 1.9e-10 40.8 0.0 7.8 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ90170.1 - 5.2e-22 78.5 8.8 0.0002 22.2 0.1 6.6 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EAQ90170.1 - 3.9e-07 28.8 0.0 0.042 12.2 0.0 4.2 4 0 0 4 4 4 2 Transferase family DUF3658 PF12395.3 EAQ90170.1 - 0.048 13.2 0.0 20 4.7 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function YecM PF06185.7 EAQ90170.1 - 0.055 12.6 0.0 2.9 7.0 0.0 2.6 2 0 0 2 2 2 0 YecM protein RHH_3 PF12651.2 EAQ90170.1 - 0.25 11.1 0.6 4.5 7.0 0.1 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix domain SSURE PF11966.3 EAQ90170.1 - 0.99 9.0 0.0 2.7 7.6 0.0 1.7 1 0 0 1 1 1 0 Fibronectin-binding repeat Rab_eff_C PF04698.7 EAQ90170.1 - 3.5 5.6 0.1 5.8 4.9 0.1 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus AATase PF07247.7 EAQ90170.1 - 7.3 5.0 0.0 1.5e+02 0.6 0.0 3.0 4 0 0 4 4 4 0 Alcohol acetyltransferase Ribosomal_60s PF00428.14 EAQ90170.1 - 8.9 6.7 8.9 1.8 9.0 2.4 2.8 2 0 0 2 2 1 0 60s Acidic ribosomal protein ABC_tran PF00005.22 EAQ90171.1 - 1.4e-40 138.7 0.3 1.8e-28 99.5 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAQ90171.1 - 1.6e-30 106.4 16.6 2.8e-29 102.3 8.3 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.1 EAQ90171.1 - 2.1e-07 31.2 0.1 0.17 11.7 0.0 3.4 2 1 0 3 3 3 2 AAA domain T2SE PF00437.15 EAQ90171.1 - 4.2e-07 29.1 0.0 0.023 13.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EAQ90171.1 - 2.5e-06 27.6 0.2 0.061 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EAQ90171.1 - 3.2e-06 26.5 0.6 0.08 12.1 0.0 4.0 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EAQ90171.1 - 1.1e-05 25.9 0.4 0.077 13.4 0.1 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EAQ90171.1 - 2.7e-05 24.3 0.5 0.13 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAQ90171.1 - 4.8e-05 22.8 0.1 0.018 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ90171.1 - 5.3e-05 22.4 0.3 0.023 13.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EAQ90171.1 - 0.00012 21.5 0.4 0.094 12.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EAQ90171.1 - 0.00023 21.0 0.4 0.057 13.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EAQ90171.1 - 0.00024 21.0 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EAQ90171.1 - 0.00025 21.4 0.6 0.051 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAQ90171.1 - 0.00045 19.9 0.8 0.62 9.7 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EAQ90171.1 - 0.0008 19.0 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EAQ90171.1 - 0.00099 18.6 0.1 0.43 10.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EAQ90171.1 - 0.0011 19.7 0.3 2 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAQ90171.1 - 0.0013 18.2 1.3 0.29 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 EAQ90171.1 - 0.0028 17.7 0.1 1.5 9.0 0.0 3.2 3 0 0 3 3 3 1 RNA helicase cobW PF02492.14 EAQ90171.1 - 0.003 17.0 2.2 0.52 9.7 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EAQ90171.1 - 0.0038 16.7 1.5 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EAQ90171.1 - 0.0054 16.4 0.4 0.42 10.2 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EAQ90171.1 - 0.0055 16.3 1.6 0.29 10.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Septin PF00735.13 EAQ90171.1 - 0.0069 15.4 0.2 2.6 6.9 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_18 PF13238.1 EAQ90171.1 - 0.0087 16.3 0.9 2.1 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EAQ90171.1 - 0.011 15.2 0.3 0.78 9.2 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EAQ90171.1 - 0.013 15.6 0.1 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EAQ90171.1 - 0.019 14.7 0.8 0.93 9.2 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EAQ90171.1 - 0.022 13.8 0.2 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EAQ90171.1 - 0.022 14.6 0.3 0.37 10.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.4 EAQ90171.1 - 0.033 12.7 0.3 4.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 EAQ90171.1 - 0.034 13.6 0.7 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EAQ90171.1 - 0.039 12.8 0.1 8.4 5.1 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 EAQ90171.1 - 0.067 12.8 0.9 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EAQ90171.1 - 0.071 12.8 1.5 2.4 7.8 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EAQ90171.1 - 0.075 11.6 0.1 0.13 10.8 0.1 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EAQ90171.1 - 0.079 12.1 0.1 0.99 8.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EAQ90171.1 - 0.12 11.9 0.9 9.9 5.6 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EAQ90171.1 - 0.93 9.2 2.3 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Exo_endo_phos_2 PF14529.1 EAQ90174.1 - 1.8e-14 53.3 0.0 4e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ90174.1 - 1.8e-06 28.0 0.0 6.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EAQ90174.1 - 6.9e-06 25.5 0.0 0.0013 18.0 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EAQ90174.1 - 0.027 14.7 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EAQ90175.1 - 1.2e-29 103.2 0.0 2.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ90175.1 - 1.9e-12 46.8 0.0 5.9e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ90175.1 - 1.9e-05 24.7 0.1 4.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Alpha_E1_glycop PF01589.11 EAQ90175.1 - 0.0068 14.7 0.1 2.3 6.4 0.0 2.3 2 0 0 2 2 2 2 Alphavirus E1 glycoprotein zf-RVT PF13966.1 EAQ90175.1 - 0.0081 16.4 0.1 0.076 13.3 0.0 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Atg14 PF10186.4 EAQ90175.1 - 0.045 12.7 6.5 0.12 11.3 4.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 EAQ90175.1 - 0.91 9.3 4.2 2.4 7.9 2.9 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EAQ90175.1 - 2.5 5.5 4.9 4 4.8 3.4 1.2 1 0 0 1 1 1 0 Prominin OmpH PF03938.9 EAQ90175.1 - 3.6 7.5 15.9 2.3 8.1 9.2 2.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Chitin_bind_1 PF00187.14 EAQ90177.1 - 9e-16 57.5 74.9 7.7e-08 32.1 11.6 4.8 3 3 1 4 4 4 3 Chitin recognition protein Mucin PF01456.12 EAQ90177.1 - 0.086 12.6 28.6 0.24 11.1 8.6 2.9 3 0 0 3 3 3 0 Mucin-like glycoprotein MIP PF00230.15 EAQ90178.1 - 6.7e-38 130.4 14.8 1.4e-37 129.3 10.3 1.5 1 1 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 EAQ90179.1 - 8.2e-48 162.9 58.5 2.1e-47 161.5 38.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ90179.1 - 6.2e-22 77.5 26.1 8.1e-22 77.1 18.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EAQ90179.1 - 2.3e-12 46.2 12.8 2.3e-12 46.2 8.9 3.0 4 0 0 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 EAQ90179.1 - 0.00035 19.1 9.4 0.00035 19.1 6.5 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein DUF3980 PF13140.1 EAQ90179.1 - 1.5 9.1 9.1 0.76 10.0 0.6 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) Zn_clus PF00172.13 EAQ90180.1 - 8.2e-06 25.6 8.2 1.3e-05 24.9 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Picorna_P3A PF06363.6 EAQ90180.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein Helitron_like_N PF14214.1 EAQ90182.1 - 1.7e-50 171.3 2.0 3.7e-50 170.2 1.4 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ90182.1 - 3.6e-26 91.9 0.0 3.9e-22 78.6 0.0 2.5 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EAQ90182.1 - 1.5e-06 27.8 0.0 8.4e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ90182.1 - 0.01 15.9 0.0 0.034 14.3 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ90182.1 - 0.016 14.9 0.1 0.079 12.7 0.1 2.2 1 0 0 1 1 1 0 Part of AAA domain XPA_N PF01286.13 EAQ90182.1 - 0.019 14.6 1.9 0.049 13.3 1.3 1.6 1 0 0 1 1 1 0 XPA protein N-terminal Torsin PF06309.6 EAQ90182.1 - 0.36 10.7 0.0 0.96 9.3 0.0 1.6 1 0 0 1 1 1 0 Torsin Ribonuc_P_40 PF08584.6 EAQ90182.1 - 0.69 8.8 0.0 1.3 7.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Herpes_Helicase PF02689.9 EAQ90182.1 - 1.3 6.7 0.0 2.6 5.6 0.0 1.4 2 0 0 2 2 2 0 Helicase Formyl_trans_N PF00551.14 EAQ90183.1 - 1.3e-34 119.2 0.1 1.7e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EAQ90183.1 - 1.7e-07 30.5 0.0 4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EAQ90183.1 - 0.0039 16.8 0.0 0.0097 15.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain RVT_1 PF00078.22 EAQ90184.1 - 1.9e-37 128.6 0.0 3.1e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ90184.1 - 4.3e-11 42.4 0.0 1.5e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Acetyltransf_1 PF00583.19 EAQ90186.1 - 1.2e-11 44.4 0.1 2.7e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ90186.1 - 1.4e-09 37.9 0.0 7.3e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAQ90186.1 - 9.4e-07 28.9 0.4 0.00018 21.6 0.1 2.2 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAQ90186.1 - 9.4e-06 25.4 0.1 3.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ90186.1 - 0.0025 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.1 EAQ90186.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EAQ90186.1 - 0.081 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Cofilin_ADF PF00241.15 EAQ90187.1 - 0.00014 21.7 0.4 0.069 13.0 0.0 2.0 1 1 1 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_3 PF00933.16 EAQ90188.1 - 1.9e-92 309.4 0.0 2.6e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ90188.1 - 4.4e-52 176.8 0.0 7.3e-51 172.8 0.0 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ90188.1 - 1.3e-20 73.0 0.2 3.7e-20 71.6 0.2 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain SSF PF00474.12 EAQ90189.1 - 1.5e-08 33.7 30.5 4.8e-08 32.0 20.2 2.3 1 1 0 1 1 1 1 Sodium:solute symporter family Phospholip_A2_3 PF09056.6 EAQ90191.1 - 1.1e-33 115.7 3.3 2.2e-32 111.5 2.3 2.1 1 1 0 1 1 1 1 Prokaryotic phospholipase A2 Transglut_core PF01841.14 EAQ90191.1 - 0.11 12.7 0.3 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily adh_short PF00106.20 EAQ90192.1 - 5.3e-11 42.7 0.1 8.3e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RVT_1 PF00078.22 EAQ90193.1 - 2.6e-21 75.9 0.0 5.1e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ90193.1 - 4.1e-17 62.4 2.2 5.9e-17 61.8 0.1 2.5 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.12 EAQ90193.1 - 3.6e-09 36.5 0.4 3.6e-09 36.5 0.3 3.4 3 0 0 3 3 3 1 Retrotransposon gag protein Chromo PF00385.19 EAQ90193.1 - 8.2e-05 22.2 0.2 0.00032 20.3 0.2 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EAQ90193.1 - 0.00018 21.9 0.0 0.00043 20.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EAQ90193.1 - 0.00053 19.7 7.4 0.0015 18.3 5.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.5 EAQ90193.1 - 0.00057 19.2 0.0 0.0013 18.0 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF869 PF05911.6 EAQ90193.1 - 0.0013 17.0 3.4 0.29 9.3 0.1 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF869) DUF1110 PF06533.7 EAQ90193.1 - 0.012 15.4 6.2 0.028 14.2 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Peptidase_A2E PF12382.3 EAQ90193.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase PspA_IM30 PF04012.7 EAQ90193.1 - 0.11 11.7 16.4 0.15 11.4 8.7 2.7 2 0 0 2 2 2 0 PspA/IM30 family Asp_protease PF09668.5 EAQ90193.1 - 0.37 10.3 0.0 0.75 9.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease IncA PF04156.9 EAQ90193.1 - 5 6.6 8.5 3.6 7.1 0.2 3.3 3 0 0 3 3 3 0 IncA protein Dimer_Tnp_hAT PF05699.9 EAQ90194.1 - 1.9e-12 46.6 0.1 4.6e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PIF1 PF05970.9 EAQ90195.1 - 2.4e-13 49.7 0.1 4.9e-06 25.7 0.0 2.9 2 1 1 3 3 3 2 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ90195.1 - 0.00041 20.4 0.0 0.0022 18.1 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ90195.1 - 0.00042 18.2 0.0 0.0011 16.8 0.0 1.5 2 0 0 2 2 2 1 Helicase DUF3638 PF12340.3 EAQ90196.1 - 3.3e-104 346.8 0.3 5.4e-104 346.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EAQ90196.1 - 6.6e-14 50.7 0.1 1.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-CCHC PF00098.18 EAQ90197.1 - 2.9e-07 30.0 3.1 7.1e-07 28.8 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EAQ90197.1 - 0.0031 16.9 1.1 0.0078 15.6 0.8 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 EAQ90197.1 - 0.1 12.3 0.9 0.2 11.3 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle FAR1 PF03101.10 EAQ90198.1 - 0.00027 21.3 0.0 0.00042 20.7 0.0 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF3505 PF12013.3 EAQ90199.1 - 3.4e-18 65.8 0.1 2.9e-10 40.3 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EAQ90199.1 - 0.015 15.4 0.6 0.015 15.4 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain LRS4 PF10422.4 EAQ90199.1 - 0.88 8.8 3.6 1.8 7.8 2.5 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Nop14 PF04147.7 EAQ90199.1 - 8.5 4.1 16.0 12 3.6 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family PIF1 PF05970.9 EAQ90200.1 - 2.1e-29 102.5 0.0 8.7e-23 80.8 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ90200.1 - 3e-06 26.9 0.0 5.7e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 EAQ90200.1 - 7.4e-05 20.7 0.0 0.00054 17.8 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EAQ90200.1 - 9.1e-05 22.5 0.0 0.00036 20.6 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ90200.1 - 0.00038 20.1 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 EAQ90200.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Torsin AA_permease PF00324.16 EAQ90203.1 - 1.1e-79 268.0 28.6 1.3e-79 267.7 19.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ90203.1 - 4.5e-25 88.0 28.2 5.6e-25 87.7 19.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ90204.1 - 4.2e-61 206.7 29.1 5.3e-53 180.0 14.9 2.4 2 1 1 3 3 3 2 Amino acid permease Tyrosinase PF00264.15 EAQ90204.1 - 9.3e-29 101.1 0.1 1.3e-28 100.6 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase AA_permease PF00324.16 EAQ90204.1 - 4.5e-07 28.5 22.9 4.5e-07 28.5 15.9 1.5 2 0 0 2 2 2 1 Amino acid permease Dioxygenase_C PF00775.16 EAQ90205.1 - 5e-12 45.4 0.0 8.7e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase APS_kinase PF01583.15 EAQ90205.1 - 0.00061 19.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF2638 PF10937.3 EAQ90206.1 - 5.6e-39 133.6 0.6 6.5e-39 133.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Cyto_heme_lyase PF01265.12 EAQ90207.1 - 6.6e-89 297.9 0.1 8e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF647 PF04884.9 EAQ90208.1 - 4.3e-101 337.3 0.4 5.6e-101 336.9 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis GHMP_kinases_N PF00288.21 EAQ90209.1 - 6.4e-10 38.9 3.7 1.6e-09 37.6 1.3 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain E1-E2_ATPase PF00122.15 EAQ90211.1 - 1.2e-62 211.0 6.4 2.2e-62 210.1 4.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ90211.1 - 9.6e-27 94.7 0.0 3.7e-26 92.8 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EAQ90211.1 - 1.5e-21 76.7 0.0 1.5e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EAQ90211.1 - 2.8e-15 55.4 0.0 7.9e-15 54.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EAQ90211.1 - 4.2e-14 52.2 0.0 9.3e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAQ90211.1 - 7e-13 49.1 0.1 4.5e-12 46.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ90211.1 - 6.7e-06 25.8 2.6 3.9e-05 23.3 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 EAQ90212.1 - 7.6e-45 153.2 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EAQ90212.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Reticulon DUF1779 PF08680.5 EAQ90214.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) Na_trans_assoc PF06512.8 EAQ90214.1 - 0.46 10.4 1.9 0.8 9.6 1.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Glyco_hydro_43 PF04616.9 EAQ90215.1 - 1e-30 106.8 0.2 1.2e-30 106.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HET PF06985.6 EAQ90216.1 - 1.8e-26 92.9 0.2 4.3e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hemerythrin PF01814.18 EAQ90217.1 - 2.5e-08 34.1 1.7 4.3e-08 33.3 0.5 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain EzrA PF06160.7 EAQ90217.1 - 0.048 11.8 0.0 0.064 11.4 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ILVD_EDD PF00920.16 EAQ90218.1 - 2.5e-153 511.2 0.9 2.9e-153 511.0 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family Nucleos_tra2_C PF07662.8 EAQ90219.1 - 1.3e-67 227.3 1.1 1.3e-67 227.3 0.8 2.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EAQ90219.1 - 4.7e-21 74.9 1.4 4.7e-21 74.9 1.0 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus PNK3P PF08645.6 EAQ90220.1 - 4.3e-38 130.2 0.0 7.1e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EAQ90220.1 - 3.4e-29 101.5 0.0 2.4e-28 98.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAQ90220.1 - 1.4e-05 24.3 0.0 0.004 16.2 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin AAA_22 PF13401.1 EAQ90220.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ90220.1 - 0.027 14.7 0.2 8.5 6.7 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EAQ90220.1 - 0.067 14.0 0.1 0.23 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAQ90220.1 - 0.088 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.19 EAQ90221.1 - 5.4e-111 371.3 24.4 6.3e-111 371.1 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ90221.1 - 3.3e-28 98.4 36.6 4.4e-28 97.9 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ90221.1 - 1.4e-06 26.9 25.5 0.00054 18.4 1.8 3.6 3 1 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 EAQ90221.1 - 0.00024 19.9 0.7 0.00024 19.9 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 EAQ90221.1 - 0.002 17.8 0.4 0.037 13.8 0.0 3.1 2 0 0 2 2 2 1 MFS_1 like family Rick_17kDa_Anti PF05433.10 EAQ90221.1 - 2.1 8.0 5.8 0.23 11.1 0.3 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain HpaB_N PF11794.3 EAQ90222.1 - 0.018 14.4 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Selenoprotein_S PF06936.6 EAQ90222.1 - 0.046 13.2 1.8 0.065 12.7 1.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) RuvA_C PF07499.8 EAQ90222.1 - 0.16 12.1 0.6 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 RuvA, C-terminal domain adh_short PF00106.20 EAQ90223.1 - 1.8e-15 57.2 0.2 5.6e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ90223.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ90223.1 - 0.00023 20.8 0.2 0.00039 20.1 0.2 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EAQ90223.1 - 0.055 13.5 0.2 0.34 10.9 0.2 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Toprim_3 PF13362.1 EAQ90223.1 - 0.057 13.6 0.2 0.72 10.1 0.2 2.2 2 0 0 2 2 2 0 Toprim domain Polysacc_synt_2 PF02719.10 EAQ90223.1 - 0.082 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF607 PF04678.8 EAQ90224.1 - 6.1e-39 133.8 0.1 1.7e-38 132.3 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Acetyltransf_8 PF13523.1 EAQ90225.1 - 3.2e-26 92.0 0.1 4.9e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_11 PF14833.1 EAQ90227.1 - 0.00041 20.4 0.0 0.00061 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase BNR_3 PF13859.1 EAQ90228.1 - 3.5e-09 36.1 0.0 4.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-like domain BNR_2 PF13088.1 EAQ90228.1 - 6.1e-09 35.5 0.2 1.6e-05 24.3 0.1 3.6 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.15 EAQ90228.1 - 0.0015 18.0 11.2 0.044 13.6 0.1 3.4 3 0 0 3 3 3 2 BNR/Asp-box repeat DUF4185 PF13810.1 EAQ90228.1 - 0.014 14.3 0.4 1.6 7.5 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4185) Glyco_hydro_76 PF03663.9 EAQ90230.1 - 2.1e-146 488.0 2.1 2.6e-146 487.7 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Gcd10p PF04189.8 EAQ90231.1 - 2.1e-64 217.5 0.0 3e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family P21-Arc PF04062.9 EAQ90232.1 - 1.4e-78 262.6 0.0 1.6e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EAQ90232.1 - 0.087 12.8 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide COesterase PF00135.23 EAQ90234.1 - 9.4e-99 331.5 0.0 1.3e-98 331.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ90234.1 - 0.0082 15.7 0.4 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ90234.1 - 0.033 13.3 1.2 0.099 11.8 0.5 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family NAD_binding_10 PF13460.1 EAQ90235.1 - 2.2e-09 37.5 0.0 2.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ90235.1 - 5.8e-05 22.4 0.0 6.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAQ90235.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EAQ90235.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Asp PF00026.18 EAQ90236.1 - 9.3e-49 166.3 0.7 1.6e-27 96.6 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ90236.1 - 2.5e-06 27.5 5.1 6.9e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAQ90236.1 - 0.0078 15.7 0.1 0.24 10.9 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EAQ90236.1 - 0.011 16.2 0.0 0.56 10.7 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 EAQ90236.1 - 0.041 13.6 0.1 0.93 9.3 0.0 2.9 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease MULE PF10551.4 EAQ90237.1 - 1.2e-18 67.0 0.0 2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF3440 PF11922.3 EAQ90237.1 - 0.037 13.5 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Transglut_core PF01841.14 EAQ90239.1 - 2.5e-09 37.3 0.7 2.6e-08 34.0 0.5 2.5 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.10 EAQ90239.1 - 2.8e-09 36.5 1.6 5.4e-09 35.6 1.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain DUF1996 PF09362.5 EAQ90241.1 - 1.2e-52 178.9 2.0 1.4e-52 178.7 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_43 PF04616.9 EAQ90242.1 - 5.8e-11 42.0 2.7 1.3e-10 40.8 1.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S8 PF00082.17 EAQ90244.1 - 5e-11 42.2 0.0 1.1e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Annexin PF00191.15 EAQ90245.1 - 2e-10 40.3 0.7 0.011 15.6 0.0 4.5 4 0 0 4 4 4 2 Annexin zf-Di19 PF05605.7 EAQ90245.1 - 1 9.5 8.8 0.11 12.5 0.4 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EAQ90245.1 - 9.6 6.7 21.1 4.2 7.9 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger Pro-kuma_activ PF09286.6 EAQ90246.1 - 2.3e-20 73.1 0.2 3.2e-11 43.4 0.1 2.4 1 1 1 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EAQ90246.1 - 6.6e-05 22.1 0.0 0.00015 21.0 0.0 1.5 2 0 0 2 2 2 1 Subtilase family Alpha-amylase PF00128.19 EAQ90247.1 - 5.9e-24 85.0 0.0 5e-21 75.4 0.0 2.5 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EAQ90247.1 - 6.1e-17 61.9 0.1 1e-16 61.1 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EAQ90247.1 - 3.4e-08 33.0 0.0 6.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAQ90247.1 - 1.5e-06 28.3 0.0 3.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 His_biosynth PF00977.16 EAQ90247.1 - 0.38 9.9 0.0 0.7 9.1 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Alpha-amylase PF00128.19 EAQ90248.1 - 5.3e-60 203.4 0.3 7.4e-60 202.9 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EAQ90248.1 - 2.4e-26 91.6 0.6 4.9e-26 90.6 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) FAD_binding_2 PF00890.19 EAQ90250.1 - 2.5e-90 303.3 0.3 2.8e-90 303.1 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ90250.1 - 3e-07 30.3 0.5 1.3e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ90250.1 - 2.1e-05 24.4 0.0 0.0018 18.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ90250.1 - 6.5e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EAQ90250.1 - 6.9e-05 22.0 0.0 0.00017 20.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EAQ90250.1 - 0.00012 21.0 0.1 0.00012 21.0 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EAQ90250.1 - 0.00037 19.1 3.1 0.0034 15.8 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EAQ90250.1 - 0.00075 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EAQ90250.1 - 0.00095 18.1 0.8 0.0026 16.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ90250.1 - 0.0021 18.1 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ90250.1 - 0.0063 15.6 0.0 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAQ90250.1 - 0.021 13.7 0.1 0.046 12.6 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD-oxidase_C PF02913.14 EAQ90251.1 - 1.1e-59 201.7 0.7 1.5e-59 201.3 0.5 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAQ90251.1 - 1.1e-40 138.2 0.0 2.1e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Y_phosphatase3 PF13350.1 EAQ90252.1 - 2e-40 138.6 0.0 2.6e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EAQ90252.1 - 0.00022 20.6 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EAQ90252.1 - 0.0078 15.5 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EAQ90252.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EAQ90252.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 EAQ90252.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Oxysterol_BP PF01237.13 EAQ90253.1 - 6e-64 215.7 0.0 6.2e-63 212.4 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein Sugar_tr PF00083.19 EAQ90254.1 - 3.3e-96 322.5 17.1 3.8e-96 322.4 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ90254.1 - 2.7e-30 105.2 26.9 2.7e-21 75.7 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 EAQ90255.1 - 1.3e-37 129.2 0.1 2.7e-37 128.2 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Ank_2 PF12796.2 EAQ90257.1 - 1.2e-11 44.7 0.0 1.4e-09 38.1 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ90257.1 - 2.2e-09 36.6 0.0 0.00043 19.9 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EAQ90257.1 - 3.2e-08 33.0 0.1 0.00058 19.8 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 EAQ90257.1 - 5.6e-08 32.7 0.0 2.6e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ90257.1 - 1e-07 32.2 0.0 3.6e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_14 PF13428.1 EAQ90257.1 - 0.27 11.9 4.2 11 7.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EAQ90258.1 - 3.1e-09 36.0 0.2 5.2e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EAQ90259.1 - 1.5e-20 73.7 0.1 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ90259.1 - 2.4e-10 40.3 0.1 2.8e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ90259.1 - 5.7e-06 25.9 0.0 6.7e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ90259.1 - 0.0015 17.4 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.1 EAQ90259.1 - 0.0064 16.2 0.0 0.0075 16.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ90259.1 - 0.013 15.5 0.2 0.024 14.6 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EAQ90259.1 - 0.039 14.0 0.5 0.1 12.7 0.3 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EAQ90259.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CRCB PF02537.10 EAQ90259.1 - 0.056 13.3 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 CrcB-like protein Polysacc_synt_2 PF02719.10 EAQ90259.1 - 0.059 12.2 0.1 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EAQ90259.1 - 0.06 12.0 0.1 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.27 EAQ90260.1 - 0.00016 21.4 0.3 0.0047 16.7 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat AAA_19 PF13245.1 EAQ90261.1 - 0.0021 17.7 0.0 0.018 14.7 0.0 2.4 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 EAQ90261.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ90261.1 - 0.038 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain 6PF2K PF01591.13 EAQ90261.1 - 0.049 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.15 EAQ90261.1 - 0.051 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 EAQ90261.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EAQ90261.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EAQ90261.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EAQ90261.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Fructosamin_kin PF03881.9 EAQ90262.1 - 2.1e-20 72.8 0.0 2.7e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAQ90262.1 - 0.00022 21.0 0.1 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sugar_tr PF00083.19 EAQ90263.1 - 1.1e-100 337.3 33.4 1.5e-100 336.9 23.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ90263.1 - 2.4e-24 85.6 37.8 5.2e-22 78.0 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ90263.1 - 0.0086 14.5 0.2 0.0086 14.5 0.1 3.9 2 2 2 4 4 4 2 MFS/sugar transport protein Pkinase PF00069.20 EAQ90264.1 - 1.6e-06 27.4 0.0 2.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAQ90264.1 - 0.0011 18.7 1.1 0.0016 18.2 0.2 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EAQ90264.1 - 0.0052 15.8 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EAQ90264.1 - 0.039 13.1 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) BAF1_ABF1 PF04684.8 EAQ90265.1 - 1.1 7.9 2.8 1.6 7.4 2.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ank_2 PF12796.2 EAQ90266.1 - 4e-27 94.3 0.2 1.6e-14 53.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ90266.1 - 2.1e-26 91.7 7.0 1.7e-11 44.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ90266.1 - 7.9e-26 88.5 4.4 2.1e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EAQ90266.1 - 1e-22 79.6 13.0 1.6e-07 31.3 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ90266.1 - 1.3e-18 65.1 0.3 0.00046 20.1 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.16 EAQ90266.1 - 1.4e-05 24.9 0.8 2.4e-05 24.1 0.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EAQ90266.1 - 0.0063 16.7 0.5 0.011 15.9 0.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor adh_short PF00106.20 EAQ90267.1 - 3.6e-20 72.5 0.2 5.9e-20 71.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ90267.1 - 7.7e-13 48.4 0.1 1.2e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ90267.1 - 4.5e-07 29.5 0.0 7.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EAQ90267.1 - 2.3e-05 24.2 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ90267.1 - 0.00089 19.3 0.6 0.0018 18.3 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ90267.1 - 0.044 13.0 0.2 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family RVT_1 PF00078.22 EAQ90268.1 - 4.1e-34 117.7 0.0 6.7e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ90268.1 - 1.1e-05 25.0 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Pkinase PF00069.20 EAQ90269.1 - 7.8e-09 35.0 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAQ90269.1 - 6.9e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EAQ90269.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EAQ90269.1 - 0.017 14.8 0.5 0.04 13.6 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAQ90269.1 - 0.057 12.4 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase FAD_binding_3 PF01494.14 EAQ90270.1 - 4.1e-15 55.7 0.4 2.8e-07 29.9 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EAQ90270.1 - 1.4e-06 27.4 0.0 0.00043 19.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ90270.1 - 0.0013 17.6 0.2 0.0041 16.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ90270.1 - 0.021 14.8 0.1 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAQ90270.1 - 0.11 11.0 0.1 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 EAQ90271.1 - 7e-36 123.6 45.5 7e-36 123.6 31.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ90271.1 - 8.4e-05 20.9 5.5 0.00013 20.3 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EAQ90272.1 - 9e-12 44.4 0.0 1.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ90272.1 - 2.2e-05 24.2 1.4 2.2e-05 24.2 1.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 EAQ90273.1 - 8.5e-36 123.3 0.0 9.8e-34 116.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_1 PF02899.12 EAQ90274.1 - 2.4 8.3 5.5 5.1 7.3 0.1 3.4 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain AAA_22 PF13401.1 EAQ90277.1 - 0.00039 20.5 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ90277.1 - 0.00041 20.3 0.1 0.001 19.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAQ90277.1 - 0.0017 19.2 0.1 0.0089 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ90277.1 - 0.0052 16.4 0.1 0.027 14.1 0.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 EAQ90277.1 - 0.01 16.1 0.0 0.042 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EAQ90277.1 - 0.026 13.6 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EAQ90277.1 - 0.029 13.8 0.1 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EAQ90277.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EAQ90277.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EAQ90277.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EAQ90277.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAQ90277.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ank_2 PF12796.2 EAQ90278.1 - 7.3e-55 183.2 2.8 2.3e-16 59.8 0.1 8.8 5 3 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ90278.1 - 2.7e-34 116.9 15.7 2.6e-06 27.7 0.0 10.5 11 0 0 11 11 11 6 Ankyrin repeats (many copies) Cellulase PF00150.13 EAQ90278.1 - 9.9e-33 113.5 0.2 1.6e-32 112.8 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_3 PF13606.1 EAQ90278.1 - 2e-29 98.7 16.1 0.00012 21.9 0.0 13.5 14 1 0 14 14 14 7 Ankyrin repeat Ank PF00023.25 EAQ90278.1 - 2.8e-29 99.4 22.8 1.5e-07 30.9 0.0 14.8 14 2 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.1 EAQ90278.1 - 5.9e-26 89.9 21.3 2.6e-05 24.3 0.1 10.4 9 1 1 10 10 10 6 Ankyrin repeats (many copies) TPR_19 PF14559.1 EAQ90278.1 - 0.0038 17.5 0.4 0.04 14.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat RNA_pol_Rpb6 PF01192.17 EAQ90278.1 - 0.03 14.0 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb6 Hexapep_2 PF14602.1 EAQ90278.1 - 0.079 12.5 0.2 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase PPR_3 PF13812.1 EAQ90278.1 - 2.2 8.7 4.5 9 6.8 0.0 4.2 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Fringe PF02434.11 EAQ90279.1 - 0.00043 19.5 2.7 0.0027 16.9 1.9 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EAQ90279.1 - 0.037 13.6 0.3 0.094 12.2 0.2 1.7 1 1 0 1 1 1 0 Galactosyltransferase DUF2165 PF09933.4 EAQ90280.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Tcp11 PF05794.8 EAQ90281.1 - 1.9e-40 138.9 0.0 4.1e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 11 DUF3433 PF11915.3 EAQ90282.1 - 1.5e-14 53.9 2.8 4.6e-14 52.3 1.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Peptidase_M1 PF01433.15 EAQ90283.1 - 2.7e-134 448.1 0.2 4.6e-134 447.3 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EAQ90283.1 - 4e-73 246.4 0.0 2e-72 244.2 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EAQ90283.1 - 9.3e-21 74.2 2.5 4.3e-20 72.0 0.1 2.6 2 1 1 3 3 3 1 Peptidase MA superfamily DUF45 PF01863.12 EAQ90283.1 - 0.0051 16.6 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EAQ90283.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 SprT-like family DUF1215 PF06744.7 EAQ90283.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) zf-CCCH PF00642.19 EAQ90284.1 - 1.9e-11 43.3 23.6 5.1e-06 26.0 0.7 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IBR PF01485.16 EAQ90284.1 - 2.1e-06 27.4 6.5 2.1e-06 27.4 4.5 3.2 3 0 0 3 3 3 1 IBR domain RRM_6 PF14259.1 EAQ90284.1 - 1.9e-05 24.5 0.0 0.017 15.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HycA_repressor PF11046.3 EAQ90284.1 - 0.021 14.7 0.2 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons WD-3 PF09765.4 EAQ90284.1 - 0.029 13.6 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 WD-repeat region zf-CCCH_2 PF14608.1 EAQ90284.1 - 0.24 11.4 25.5 0.051 13.5 3.2 3.9 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Ank_2 PF12796.2 EAQ90285.1 - 3.4e-40 136.2 0.0 3.2e-12 46.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ90285.1 - 4.5e-38 127.1 0.1 1.4e-06 27.8 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EAQ90285.1 - 2e-35 120.0 2.5 4e-10 39.5 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ90285.1 - 1.3e-30 105.1 0.9 1.3e-09 38.2 0.1 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ90285.1 - 8.2e-26 87.5 0.1 7.4e-05 22.6 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat tRNA-synt_His PF13393.1 EAQ90286.1 - 1.7e-33 116.0 0.0 1.2e-32 113.2 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EAQ90286.1 - 3.1e-15 56.1 0.0 4.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAQ90286.1 - 1.9e-08 34.1 0.1 6.2e-08 32.4 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EAQ90286.1 - 0.00027 19.8 0.3 0.021 13.5 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) DUF1479 PF07350.7 EAQ90288.1 - 4.5e-165 549.1 0.0 5.6e-165 548.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) IDO PF01231.13 EAQ90289.1 - 5.2e-08 31.7 0.0 5.4e-07 28.3 0.0 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase adh_short PF00106.20 EAQ90291.1 - 2.7e-20 72.9 0.5 3.4e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ90291.1 - 8.6e-12 45.0 0.1 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ90291.1 - 4e-08 32.9 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ90291.1 - 0.00075 19.5 1.9 0.0022 18.0 1.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EAQ90291.1 - 0.0014 17.6 0.4 0.0026 16.8 0.2 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EAQ90291.1 - 0.074 13.1 0.1 0.15 12.1 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase VWA PF00092.23 EAQ90291.1 - 0.086 12.5 0.0 2 8.1 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain MFS_1 PF07690.11 EAQ90292.1 - 2.1e-18 66.1 29.0 4.2e-10 38.8 9.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MtrE PF04206.7 EAQ90292.1 - 0.061 12.3 4.4 0.54 9.2 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E ATG22 PF11700.3 EAQ90292.1 - 1.3 7.4 19.8 0.54 8.6 11.3 2.1 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like PRA1 PF03208.14 EAQ90292.1 - 2.9 7.2 8.5 3.9 6.8 1.8 3.0 3 0 0 3 3 3 0 PRA1 family protein MFS_1 PF07690.11 EAQ90297.1 - 5.5e-32 110.8 24.9 5.5e-32 110.8 17.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_4 PF08386.5 EAQ90300.1 - 1.9e-15 56.6 0.0 3.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAQ90300.1 - 1e-06 28.4 0.5 1.6e-06 27.9 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ90300.1 - 0.00045 20.1 0.0 0.0016 18.3 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 EAQ90301.1 - 0.004 15.8 0.0 0.0061 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank PF00023.25 EAQ90302.1 - 2.9e-39 130.9 0.1 4.8e-08 32.4 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EAQ90302.1 - 2.3e-38 130.4 0.4 4e-14 52.7 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAQ90302.1 - 2.4e-21 73.6 0.0 0.0037 17.3 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EAQ90302.1 - 1.4e-20 72.8 0.6 3.2e-08 33.5 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ90302.1 - 2.7e-19 69.1 1.2 8.5e-05 22.9 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) MULE PF10551.4 EAQ90302.1 - 3.9e-15 55.7 0.0 2.3e-14 53.3 0.0 2.4 1 1 1 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 EAQ90302.1 - 0.00046 18.8 0.0 0.00091 17.8 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family mTERF PF02536.9 EAQ90302.1 - 0.097 11.2 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 mTERF MFS_1 PF07690.11 EAQ90303.1 - 3e-29 101.8 27.4 3e-29 101.8 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX14 PF14880.1 EAQ90303.1 - 0.061 12.9 0.4 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly IncA PF04156.9 EAQ90303.1 - 0.27 10.8 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 IncA protein GFO_IDH_MocA_C PF02894.12 EAQ90304.1 - 4.5e-17 61.8 0.2 2.5e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain FA_hydroxylase PF04116.8 EAQ90305.1 - 2.6e-17 63.2 14.8 2.6e-17 63.2 10.3 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Zip PF02535.17 EAQ90307.1 - 0.11 11.4 3.3 0.091 11.7 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EAQ90307.1 - 1.9 7.8 10.7 2.2 7.5 7.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAD_binding_3 PF01494.14 EAQ90310.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF3429 PF11911.3 EAQ90312.1 - 9.8e-35 119.6 8.2 1.3e-34 119.2 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF4220 PF13968.1 EAQ90312.1 - 0.0061 15.6 0.9 0.0098 15.0 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) DUF4407 PF14362.1 EAQ90312.1 - 2.8 6.7 7.3 4.8 6.0 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.11 EAQ90312.1 - 6.9 6.1 29.2 3.9 6.9 18.9 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF1162 PF06650.7 EAQ90313.1 - 1.5e-89 299.9 0.0 3.3e-86 288.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EAQ90313.1 - 4.3e-42 142.3 0.1 1.4e-41 140.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EAQ90313.1 - 6.2e-07 29.5 0.4 1.7e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 ATG C terminal domain Methyltransf_23 PF13489.1 EAQ90314.1 - 3.2e-13 49.7 0.0 6.8e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ90314.1 - 3.5e-11 43.4 0.0 8.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ90314.1 - 5e-05 23.7 0.0 0.00075 19.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ90314.1 - 0.00039 19.6 0.0 0.00063 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EAQ90314.1 - 0.00062 19.3 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ90314.1 - 0.0055 17.2 0.0 0.099 13.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ90314.1 - 0.0098 16.2 0.0 0.03 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EAQ90314.1 - 0.024 14.2 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase AMP-binding PF00501.23 EAQ90316.1 - 7.7e-221 732.7 0.0 2.7e-77 259.9 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EAQ90316.1 - 2.4e-95 318.8 0.0 1.3e-20 73.4 0.0 7.0 5 2 1 6 6 6 6 Condensation domain PP-binding PF00550.20 EAQ90316.1 - 4e-35 119.8 0.9 1.9e-08 34.4 0.0 6.1 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ90316.1 - 3.5e-15 56.7 0.8 5.6e-06 27.2 0.0 4.8 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EAQ90316.1 - 0.32 9.4 0.0 45 2.3 0.0 3.3 4 0 0 4 4 4 0 Transferase family Acetyltransf_8 PF13523.1 EAQ90317.1 - 1.2e-25 90.2 0.6 2.1e-25 89.3 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EAQ90318.1 - 1.2e-50 172.4 15.7 8.4e-27 94.2 2.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ90318.1 - 4.9e-48 162.9 0.0 2.2e-31 108.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter FAD_binding_3 PF01494.14 EAQ90318.1 - 1.8e-20 73.2 0.0 1.4e-19 70.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SMC_N PF02463.14 EAQ90318.1 - 3.6e-12 45.9 1.0 0.0012 18.0 0.0 4.1 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ90318.1 - 1.1e-10 41.9 0.0 0.45 10.4 0.0 4.2 4 0 0 4 4 4 3 AAA domain MMR_HSR1 PF01926.18 EAQ90318.1 - 2.5e-06 27.4 0.2 0.03 14.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EAQ90318.1 - 4.4e-05 22.9 0.2 0.028 13.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ90318.1 - 4.4e-05 23.8 0.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ90318.1 - 9.6e-05 22.4 1.5 0.53 10.2 0.4 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EAQ90318.1 - 0.00015 22.5 0.0 0.29 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAQ90318.1 - 0.00024 20.2 0.1 0.4 9.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin NAD_binding_8 PF13450.1 EAQ90318.1 - 0.00067 19.6 0.8 0.002 18.1 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Dynamin_N PF00350.18 EAQ90318.1 - 0.00075 19.3 0.3 0.76 9.5 0.0 2.5 2 0 0 2 2 2 2 Dynamin family MobB PF03205.9 EAQ90318.1 - 0.00083 19.0 0.2 0.18 11.5 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAQ90318.1 - 0.0013 19.2 0.2 0.036 14.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EAQ90318.1 - 0.0015 18.6 0.1 5.6 7.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 EAQ90318.1 - 0.0023 16.9 0.1 0.038 12.8 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 EAQ90318.1 - 0.004 17.0 0.1 1.9 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAQ90318.1 - 0.005 16.2 0.4 0.83 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EAQ90318.1 - 0.0072 15.5 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 EAQ90318.1 - 0.0075 15.8 0.4 1.9 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EAQ90318.1 - 0.011 15.9 0.0 6.3 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAQ90318.1 - 0.013 15.3 0.2 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Trp_halogenase PF04820.9 EAQ90318.1 - 0.014 14.0 0.2 0.037 12.6 0.2 1.7 1 0 0 1 1 1 0 Tryptophan halogenase GTP_EFTU PF00009.22 EAQ90318.1 - 0.014 14.8 0.0 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.4 EAQ90318.1 - 0.035 12.7 0.1 0.76 8.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EAQ90318.1 - 0.057 12.8 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EAQ90318.1 - 0.076 12.6 0.3 5.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EAQ90318.1 - 0.082 13.1 0.3 24 5.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EAQ90318.1 - 0.11 12.4 1.2 29 4.6 0.1 3.5 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 EAQ90318.1 - 0.15 11.4 0.4 0.54 9.6 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CDC45 PF02724.9 EAQ90318.1 - 0.39 8.6 1.5 0.43 8.5 0.2 1.5 2 0 0 2 2 2 0 CDC45-like protein AAA_13 PF13166.1 EAQ90318.1 - 0.42 9.0 0.0 1.7 7.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAQ90318.1 - 0.47 9.2 0.2 1.6 7.4 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EAQ90318.1 - 0.58 9.8 0.2 37 3.9 0.0 2.9 3 0 0 3 3 2 0 Archaeal ATPase MFS_1 PF07690.11 EAQ90319.1 - 5.4e-15 54.9 47.3 7.5e-14 51.2 32.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 EAQ90321.1 - 1.1e-20 74.2 3.4 4.4e-17 62.5 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 EAQ90322.1 - 2.2e-22 79.2 0.0 2.8e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RVT_1 PF00078.22 EAQ90323.1 - 4.4e-28 98.1 0.0 9.4e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ90323.1 - 4e-16 58.7 1.1 4e-16 58.7 0.7 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase PIF1 PF05970.9 EAQ90323.1 - 6e-11 41.8 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Exo_endo_phos PF03372.18 EAQ90323.1 - 0.00013 22.0 0.4 0.00013 22.0 0.3 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.19 EAQ90327.1 - 3.5e-118 395.0 29.0 4e-118 394.8 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ90327.1 - 5.1e-20 71.4 49.8 1.2e-15 57.0 20.9 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3154 PF11351.3 EAQ90327.1 - 0.038 13.7 0.7 0.12 12.1 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) TPR_19 PF14559.1 EAQ90327.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3040 PF11239.3 EAQ90327.1 - 7 6.7 7.5 25 4.9 5.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) WD40 PF00400.27 EAQ90328.1 - 3.1e-13 49.0 18.0 0.00019 21.1 0.0 8.7 10 0 0 10 10 10 4 WD domain, G-beta repeat NACHT PF05729.7 EAQ90328.1 - 6.5e-10 38.9 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EAQ90328.1 - 0.00024 20.7 0.0 0.00073 19.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PHA_synth_III_E PF09712.5 EAQ90328.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) AAA_16 PF13191.1 EAQ90328.1 - 0.018 15.0 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EAQ90328.1 - 0.033 14.3 0.0 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EAQ90328.1 - 0.062 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TerB PF05099.8 EAQ90328.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB RNA_helicase PF00910.17 EAQ90328.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PD40 PF07676.7 EAQ90328.1 - 0.17 11.5 6.4 83 3.0 0.0 5.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat IncA PF04156.9 EAQ90329.1 - 0.00023 20.8 33.0 0.025 14.1 4.3 3.2 1 1 2 3 3 3 2 IncA protein APG6 PF04111.7 EAQ90329.1 - 0.007 15.4 34.9 0.066 12.2 5.9 3.2 1 1 2 3 3 3 3 Autophagy protein Apg6 Filament PF00038.16 EAQ90329.1 - 0.011 15.2 31.7 0.036 13.5 14.5 3.4 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 EAQ90329.1 - 0.012 15.5 39.7 0.13 12.1 6.8 4.2 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EAQ90329.1 - 0.021 14.0 35.2 0.19 10.9 0.2 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EAQ90329.1 - 0.024 12.4 45.5 0.11 10.1 30.5 2.0 1 1 1 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 EAQ90329.1 - 0.041 13.0 8.8 0.41 9.7 0.3 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EAQ90329.1 - 0.048 13.4 0.3 0.048 13.4 0.2 5.3 2 2 4 6 6 6 0 TATA element modulatory factor 1 DNA binding Tektin PF03148.9 EAQ90329.1 - 0.071 11.6 29.7 0.047 12.2 0.6 4.6 2 1 3 5 5 5 0 Tektin family HALZ PF02183.13 EAQ90329.1 - 0.48 10.1 0.1 0.48 10.1 0.1 3.9 4 0 0 4 4 2 0 Homeobox associated leucine zipper HrpA_pilin PF09589.5 EAQ90329.1 - 0.49 10.8 0.0 0.49 10.8 0.0 3.7 1 1 1 2 2 1 0 HrpA pilus formation protein Effector_1 PF04518.7 EAQ90329.1 - 1.4 7.7 12.1 0.027 13.4 1.8 2.6 1 1 1 2 2 2 0 Effector from type III secretion system DUF724 PF05266.9 EAQ90329.1 - 1.8 8.1 31.2 0.11 12.0 3.6 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF724) ERM PF00769.14 EAQ90329.1 - 1.8 8.0 45.5 1 8.8 8.8 3.2 1 1 1 3 3 3 0 Ezrin/radixin/moesin family Matrilin_ccoil PF10393.4 EAQ90329.1 - 2.7 7.4 6.2 0.27 10.6 0.2 2.5 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Prominin PF05478.6 EAQ90329.1 - 4 4.8 5.1 5.9 4.2 3.6 1.3 1 0 0 1 1 1 0 Prominin DUF3407 PF11887.3 EAQ90329.1 - 6.4 5.9 14.8 1.6 7.9 2.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3407) ADIP PF11559.3 EAQ90329.1 - 7.4 6.4 35.2 1.2 8.9 4.3 4.1 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.6 EAQ90329.1 - 7.9 6.3 32.6 0.96 9.3 0.3 4.1 1 1 3 4 4 4 0 Rabaptin-like protein BRE1 PF08647.6 EAQ90329.1 - 9.1 6.3 32.9 0.14 12.1 4.3 4.1 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase THP2 PF09432.5 EAQ90329.1 - 9.2 6.1 11.5 2.3 8.1 2.3 3.0 1 1 1 3 3 3 0 Tho complex subunit THP2 DUF4164 PF13747.1 EAQ90329.1 - 9.3 6.4 46.5 0.4 10.8 3.5 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4164) NACHT PF05729.7 EAQ90331.1 - 5.8e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EAQ90331.1 - 0.0001 21.6 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAQ90331.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EAQ90331.1 - 0.0004 20.5 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 EAQ90331.1 - 0.00043 19.9 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EAQ90331.1 - 0.0012 18.8 0.0 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAQ90331.1 - 0.0082 15.7 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) IstB_IS21 PF01695.12 EAQ90331.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein hGDE_central PF14702.1 EAQ90332.1 - 0.41 9.7 3.5 0.34 10.0 1.1 1.7 2 0 0 2 2 2 0 central domain of human glycogen debranching enzyme DUF1484 PF07363.6 EAQ90332.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) Filo_VP35 PF02097.10 EAQ90332.1 - 7.2 5.7 9.8 12 4.9 0.5 2.4 1 1 0 2 2 2 0 Filoviridae VP35 RVT_2 PF07727.9 EAQ90333.1 - 9.1e-49 165.6 0.0 8e-48 162.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ90333.1 - 9.6e-12 45.0 0.0 2.6e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ90333.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Dimer_Tnp_hAT PF05699.9 EAQ90335.1 - 0.00028 20.4 0.0 0.00067 19.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_M14 PF00246.19 EAQ90337.1 - 6.9e-60 203.0 0.1 8.5e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EAQ90337.1 - 3.3e-07 29.8 0.0 1.5e-06 27.7 0.0 2.1 3 0 0 3 3 3 1 Carboxypeptidase activation peptide ABA_WDS PF02496.11 EAQ90338.1 - 0.00088 19.3 6.1 0.81 9.8 0.6 3.8 2 0 0 2 2 2 2 ABA/WDS induced protein F-box-like PF12937.2 EAQ90339.1 - 1.2e-05 24.9 0.5 2.8e-05 23.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ90339.1 - 0.00075 19.0 1.7 0.015 14.9 0.0 2.6 2 0 0 2 2 2 1 F-box domain Prenyltrans PF00432.16 EAQ90339.1 - 0.0051 16.3 0.2 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat LtrA PF06772.6 EAQ90340.1 - 2.3e-24 85.9 15.5 4e-24 85.2 10.8 1.4 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF3328 PF11807.3 EAQ90341.1 - 0.00012 21.9 0.1 0.00022 21.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) WD40 PF00400.27 EAQ90343.1 - 3.1e-77 251.9 19.0 5.8e-12 44.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAQ90343.1 - 8.4e-09 34.0 4.4 0.00026 19.2 0.1 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ90343.1 - 0.00028 19.7 0.0 0.43 9.2 0.0 3.5 1 1 2 3 3 3 3 Nup133 N terminal like CLASP_N PF12348.3 EAQ90344.1 - 1.3e-05 24.6 0.1 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 CLASP N terminal TAN PF11640.3 EAQ90344.1 - 0.00027 20.6 0.2 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair APG6 PF04111.7 EAQ90344.1 - 0.0025 16.9 7.5 0.0065 15.5 5.2 1.6 1 0 0 1 1 1 1 Autophagy protein Apg6 HEAT PF02985.17 EAQ90344.1 - 0.0045 16.9 3.8 4.2 7.7 0.1 5.1 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 EAQ90344.1 - 0.042 13.6 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HsbA PF12296.3 EAQ90344.1 - 0.086 12.6 0.1 30 4.4 0.0 3.7 3 1 0 3 3 3 0 Hydrophobic surface binding protein A ADIP PF11559.3 EAQ90344.1 - 2 8.2 10.9 6.1 6.7 7.5 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 EAQ90344.1 - 2.9 7.8 13.3 5.6 6.9 1.3 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion NYD-SP28_assoc PF14775.1 EAQ90344.1 - 3.8 7.2 5.1 2.6 7.7 0.6 2.8 2 1 0 2 2 2 0 Sperm tail C-terminal domain Metallophos PF00149.23 EAQ90345.1 - 0.00057 19.3 2.1 0.00097 18.5 1.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAQ90345.1 - 0.007 16.2 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Amidase PF01425.16 EAQ90346.1 - 7e-18 64.7 0.5 2.1e-16 59.8 0.5 2.2 2 0 0 2 2 2 2 Amidase Condensation PF00668.15 EAQ90348.1 - 1.4e-93 313.0 0.0 3.7e-33 114.6 0.0 3.8 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 EAQ90348.1 - 3.1e-39 134.5 0.0 5e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EAQ90348.1 - 8.6e-18 64.3 0.9 2.6e-07 30.8 0.1 4.7 5 0 0 5 5 5 3 Phosphopantetheine attachment site Beta-lactamase PF00144.19 EAQ90349.1 - 3.4e-18 65.7 0.0 1.3e-09 37.5 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.3 EAQ90349.1 - 1.4e-09 37.6 0.0 3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SET PF00856.23 EAQ90350.1 - 1.2e-05 25.6 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 SET domain HCO3_cotransp PF00955.16 EAQ90351.1 - 1.3e-47 162.6 16.0 4.8e-27 94.7 5.6 2.7 1 1 1 2 2 2 2 HCO3- transporter family Glyco_hydro_32N PF00251.15 EAQ90352.1 - 5e-76 256.0 3.0 6.6e-76 255.5 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EAQ90352.1 - 0.09 13.1 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal FXa_inhibition PF14670.1 EAQ90353.1 - 1.2 9.2 8.0 0.39 10.8 0.3 2.8 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site Pectate_lyase PF03211.8 EAQ90354.1 - 2.5e-53 180.6 0.3 1.7e-44 151.8 0.0 2.1 2 0 0 2 2 2 2 Pectate lyase Cu-oxidase_2 PF07731.9 EAQ90355.1 - 5.4e-41 139.3 11.0 3.9e-37 126.8 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAQ90355.1 - 1.1e-40 138.0 8.1 5.3e-40 135.8 2.0 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EAQ90355.1 - 8.2e-35 120.0 0.2 1.7e-34 119.0 0.1 1.6 1 0 0 1 1 1 1 Multicopper oxidase F-box-like PF12937.2 EAQ90356.1 - 0.021 14.5 0.1 0.057 13.1 0.1 1.8 1 0 0 1 1 1 0 F-box-like DUF500 PF04366.7 EAQ90357.1 - 3.7e-51 171.8 0.0 6.9e-51 170.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) PGAP1 PF07819.8 EAQ90357.1 - 0.072 12.6 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein MCR_C PF04609.7 EAQ90358.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C VIT1 PF01988.14 EAQ90360.1 - 8.2e-69 231.3 1.9 9.4e-69 231.1 1.3 1.0 1 0 0 1 1 1 1 VIT family Periviscerokin PF08259.6 EAQ90360.1 - 6.6 7.1 6.4 9.3 6.7 0.6 3.1 2 0 0 2 2 2 0 Periviscerokinin family DDE_1 PF03184.14 EAQ90363.1 - 3.8e-37 127.5 0.1 7.8e-37 126.5 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ90363.1 - 1.1e-10 41.2 0.0 3.9e-10 39.3 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EAQ90363.1 - 3.5e-09 36.0 0.0 6.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ90363.1 - 5.2e-06 26.2 0.0 1.5e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF948 PF06103.6 EAQ90363.1 - 0.31 10.9 2.7 0.65 9.8 1.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YlqD PF11068.3 EAQ90363.1 - 0.4 10.7 7.9 0.91 9.5 5.5 1.5 1 0 0 1 1 1 0 YlqD protein AAA_13 PF13166.1 EAQ90363.1 - 0.47 8.8 7.5 0.83 8.0 5.2 1.3 1 0 0 1 1 1 0 AAA domain Amidoligase_2 PF12224.3 EAQ90364.1 - 1.5e-48 165.6 0.8 1.8e-48 165.3 0.5 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme Pro-NT_NN PF07421.6 EAQ90364.1 - 0.072 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Methyltransf_2 PF00891.13 EAQ90365.1 - 3e-33 114.9 0.2 4e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAQ90365.1 - 2.7e-05 24.7 0.2 0.0055 17.2 0.0 3.3 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ90365.1 - 4.2e-05 23.1 0.0 0.0006 19.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain AMP-binding PF00501.23 EAQ90367.1 - 6.8e-56 189.4 0.0 1e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EAQ90367.1 - 1.7e-24 87.3 0.0 5.7e-24 85.6 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EAQ90367.1 - 3e-10 40.2 0.0 4.9e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EAQ90367.1 - 5.9e-06 26.3 7.0 5.9e-06 26.3 4.9 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ90367.1 - 0.00019 21.1 0.5 0.00055 19.7 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2283 PF10049.4 EAQ90367.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Methyltransf_2 PF00891.13 EAQ90368.1 - 2.9e-23 82.3 0.0 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase Dimerisation PF08100.6 EAQ90368.1 - 5.1e-05 23.0 0.7 0.00015 21.5 0.1 2.2 2 0 0 2 2 2 1 Dimerisation domain HTH_IclR PF09339.5 EAQ90368.1 - 0.012 15.1 1.3 0.03 13.9 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain TrmB PF01978.14 EAQ90368.1 - 0.033 13.8 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 EAQ90368.1 - 0.068 13.2 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.2 EAQ90368.1 - 0.082 12.5 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 MarR family Glyco_hydro_61 PF03443.9 EAQ90369.1 - 1e-47 162.7 0.0 1.6e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NmrA PF05368.8 EAQ90369.1 - 1.7e-25 89.6 0.0 1.7e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EAQ90369.1 - 4.2e-14 52.9 0.2 9.5e-14 51.8 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding zf-3CxxC PF13695.1 EAQ90369.1 - 1e-13 51.2 0.1 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding domain Epimerase PF01370.16 EAQ90369.1 - 0.0046 16.4 0.0 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAQ90369.1 - 0.0074 16.2 0.8 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase DUF793 PF05633.6 EAQ90369.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) p450 PF00067.17 EAQ90370.1 - 4e-50 170.6 0.0 5.9e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EAQ90372.1 - 3.4e-23 81.9 42.1 5.8e-23 81.1 26.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ90372.1 - 1.7e-13 49.6 6.8 1.7e-13 49.6 4.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EAQ90372.1 - 3.2e-07 29.3 10.8 3.2e-07 29.3 7.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter SecE PF00584.15 EAQ90372.1 - 0.97 9.0 5.1 1.1 8.9 0.1 2.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex p450 PF00067.17 EAQ90373.1 - 4e-18 65.1 0.0 1.6e-17 63.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Cnd3 PF12719.2 EAQ90373.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Reticulon PF02453.12 EAQ90374.1 - 0.066 12.8 0.4 0.067 12.7 0.3 1.0 1 0 0 1 1 1 0 Reticulon BRO1 PF03097.13 EAQ90375.1 - 2.9e-99 332.3 0.6 8.3e-78 261.7 0.1 2.3 1 1 1 2 2 2 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EAQ90375.1 - 1.4e-69 234.2 8.8 2.6e-69 233.4 5.0 2.2 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV p450 PF00067.17 EAQ90377.1 - 1.8e-57 194.8 0.1 4.9e-45 153.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 AAA_16 PF13191.1 EAQ90378.1 - 6.8e-08 32.7 0.6 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EAQ90378.1 - 1.1e-05 25.2 0.1 3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ90378.1 - 0.00028 21.0 0.0 0.00092 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Orbi_VP2 PF00898.12 EAQ90378.1 - 0.0078 13.8 1.1 0.012 13.2 0.7 1.1 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP2 cobW PF02492.14 EAQ90378.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EAQ90378.1 - 0.041 14.3 0.0 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 EAQ90378.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EAQ90378.1 - 0.051 14.3 0.0 0.43 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAQ90378.1 - 0.07 12.5 0.0 0.32 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EAQ90378.1 - 0.14 11.5 0.5 1.1 8.6 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain AAA_29 PF13555.1 EAQ90378.1 - 0.18 11.3 0.1 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EAQ90378.1 - 0.19 12.0 0.5 0.47 10.7 0.0 1.9 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EAQ90378.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ADH_zinc_N PF00107.21 EAQ90380.1 - 2.9e-23 81.8 0.2 4.6e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ90380.1 - 1.2e-21 76.4 0.1 2.3e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EAQ90380.1 - 7.2e-06 26.9 0.0 1.7e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MTS PF05175.9 EAQ90380.1 - 0.016 14.6 0.1 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EAQ90380.1 - 0.05 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EAQ90381.1 - 2.9e-19 69.0 35.0 9.3e-19 67.3 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ90381.1 - 2.4e-05 23.1 5.9 2.4e-05 23.1 4.1 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3938 PF13074.1 EAQ90381.1 - 0.065 13.0 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF4149 PF13664.1 EAQ90381.1 - 1.1 9.4 9.2 0.17 11.9 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF1680 PF07944.7 EAQ90382.1 - 2.3e-16 59.1 0.0 3.1e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) TPR_10 PF13374.1 EAQ90384.1 - 4e-39 131.4 0.3 2.1e-14 52.9 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ90384.1 - 1.9e-38 130.2 4.2 1.5e-15 56.9 0.0 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ90384.1 - 1.3e-08 34.0 0.0 2.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EAQ90384.1 - 1.3e-08 33.9 1.6 0.0053 16.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ90384.1 - 2.1e-08 33.6 0.1 0.0018 17.8 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EAQ90384.1 - 5.3e-07 28.9 2.6 0.017 14.7 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 EAQ90384.1 - 3.7e-05 23.8 0.0 0.00015 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.12 EAQ90384.1 - 0.00032 20.3 0.5 0.52 10.3 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_22 PF13401.1 EAQ90384.1 - 0.0025 17.9 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EAQ90384.1 - 0.0027 18.3 0.0 8.3 7.2 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ90384.1 - 0.0097 15.6 0.4 8.4 6.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ90384.1 - 0.011 16.2 0.2 17 6.4 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ90384.1 - 0.061 13.7 0.0 13 6.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ90384.1 - 0.062 13.5 0.1 0.5 10.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90384.1 - 0.087 13.3 0.9 6.2 7.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ApoLp-III PF07464.6 EAQ90384.1 - 1.2 9.1 3.5 19 5.2 0.1 3.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ATP-synt_C PF00137.16 EAQ90385.1 - 4.8e-14 51.9 3.1 7e-14 51.4 2.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit C VARLMGL PF14383.1 EAQ90385.1 - 5 6.3 6.5 1.1 8.5 0.9 2.1 1 1 0 1 1 1 0 DUF761-associated sequence motif Alpha-amylase PF00128.19 EAQ90386.1 - 2.7e-21 76.2 0.0 2.2e-20 73.2 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Ferric_reduct PF01794.14 EAQ90388.1 - 3e-11 43.5 15.1 3.9e-11 43.1 9.7 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component Band_7 PF01145.20 EAQ90390.1 - 1.3e-12 48.0 0.0 1.3e-12 48.0 0.0 3.0 2 2 0 2 2 2 1 SPFH domain / Band 7 family DUF3986 PF13143.1 EAQ90390.1 - 0.0028 18.0 0.8 1.8 9.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3986) zf-C2H2 PF00096.21 EAQ90391.1 - 0.00031 20.9 8.2 0.009 16.3 0.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ90391.1 - 0.36 11.2 13.5 0.98 9.9 0.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.11 EAQ90392.1 - 2e-10 39.9 0.1 2e-10 39.9 0.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DC_STAMP PF07782.8 EAQ90392.1 - 0.12 12.0 0.2 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 DC-STAMP-like protein Fructosamin_kin PF03881.9 EAQ90393.1 - 3.3e-37 128.0 0.0 4e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAQ90393.1 - 7.9e-07 29.0 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PGAP1 PF07819.8 EAQ90394.1 - 5e-06 26.2 0.0 1.9e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EAQ90394.1 - 6.9e-06 26.1 0.0 0.00013 21.9 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EAQ90394.1 - 0.0014 18.0 0.1 0.0066 15.7 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) NACHT PF05729.7 EAQ90394.1 - 0.0042 16.7 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NHL PF01436.16 EAQ90394.1 - 0.046 13.6 0.5 0.35 10.9 0.0 2.8 3 0 0 3 3 3 0 NHL repeat Abhydrolase_5 PF12695.2 EAQ90394.1 - 0.086 12.5 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_22 PF13401.1 EAQ90394.1 - 0.2 11.7 0.0 1.3 9.2 0.0 2.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EAQ90394.1 - 0.21 11.5 3.4 1.2e+02 2.7 0.2 5.6 7 0 0 7 7 7 0 WD domain, G-beta repeat FAD_binding_4 PF01565.18 EAQ90395.1 - 1.7e-28 98.8 4.1 2.7e-28 98.1 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ90395.1 - 6.3e-12 45.2 0.2 1.6e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like DoxX_3 PF13781.1 EAQ90396.1 - 0.15 12.4 0.3 0.15 12.4 0.2 2.9 3 0 0 3 3 3 0 DoxX-like family Pkinase PF00069.20 EAQ90397.1 - 8.9e-12 44.6 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ90397.1 - 6.9e-10 38.4 0.0 1.5e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ90397.1 - 0.00049 19.2 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DLH PF01738.13 EAQ90398.1 - 1.5e-26 93.0 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAQ90398.1 - 4.9e-07 29.6 0.0 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ90398.1 - 0.0012 18.8 0.1 0.1 12.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family GST_N_3 PF13417.1 EAQ90399.1 - 0.0001 22.4 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ90399.1 - 0.0013 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PFL PF02901.10 EAQ90400.1 - 1.7e-142 476.1 0.0 1.4e-140 469.7 0.0 2.1 1 1 1 2 2 2 2 Pyruvate formate lyase Dyp_perox PF04261.7 EAQ90400.1 - 8e-32 110.2 0.0 1.3e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Dyp-type peroxidase family Pec_lyase_C PF00544.14 EAQ90402.1 - 9.6e-21 74.1 4.9 1.5e-20 73.5 3.4 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EAQ90402.1 - 0.00054 19.7 15.9 0.12 12.1 9.6 2.6 1 1 2 3 3 3 2 Right handed beta helix region Gemini_AL2 PF01440.11 EAQ90402.1 - 0.23 11.5 1.7 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Geminivirus AL2 protein TauD PF02668.11 EAQ90403.1 - 1.6e-25 90.2 0.0 2e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Porin_2 PF02530.9 EAQ90403.1 - 0.019 14.0 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Porin subfamily Ribosomal_S10 PF00338.17 EAQ90404.1 - 2.7e-28 97.6 0.5 3.2e-28 97.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L17 PF01196.14 EAQ90404.1 - 0.2 12.2 1.2 0.26 11.8 0.9 1.3 1 1 0 1 1 1 0 Ribosomal protein L17 zf-CCCH PF00642.19 EAQ90405.1 - 0.00013 21.5 3.1 0.0003 20.3 2.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 EAQ90405.1 - 0.00054 20.1 42.4 0.00054 20.1 29.4 4.6 2 1 3 5 5 5 2 Nucleoporin FG repeat region p450 PF00067.17 EAQ90406.1 - 2e-49 168.3 0.0 2.7e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3649 PF12365.3 EAQ90406.1 - 0.006 16.0 2.4 0.017 14.5 1.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3649) Pkinase PF00069.20 EAQ90408.1 - 2.2e-17 63.1 0.0 7.1e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ90408.1 - 0.00076 18.6 0.0 0.003 16.6 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EAQ90408.1 - 0.055 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Cellulase PF00150.13 EAQ90409.1 - 4.1e-17 62.2 0.1 1.4e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.9 EAQ90410.1 - 2.5e-50 171.2 0.0 3.4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EAQ90410.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) VSP PF03302.8 EAQ90410.1 - 0.28 9.7 2.9 0.45 9.0 2.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Frag1 PF10277.4 EAQ90412.1 - 1.8e-41 141.9 16.0 2.8e-41 141.3 6.5 2.6 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EAQ90412.1 - 0.00093 19.2 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.6 EAQ90413.1 - 1.5e-20 72.6 0.2 3.7e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EAQ90413.1 - 0.00025 21.4 1.2 0.43 11.3 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ90413.1 - 0.043 13.4 0.0 0.2 11.3 0.0 2.0 1 1 1 2 2 2 0 TPR repeat NRDE-2 PF08424.5 EAQ90413.1 - 0.076 11.8 0.0 0.7 8.7 0.0 2.1 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference EVE PF01878.13 EAQ90414.1 - 3.9e-47 159.8 0.0 4.9e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 EVE domain ARID PF01388.16 EAQ90416.1 - 0.00013 21.7 0.0 0.00037 20.3 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain eIF3_N PF09440.5 EAQ90417.1 - 4.5e-51 172.4 4.4 1.1e-50 171.2 2.6 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EAQ90417.1 - 1.2e-15 57.7 0.5 3e-15 56.3 0.1 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EAQ90417.1 - 0.00074 19.3 0.4 0.0023 17.6 0.1 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 PC_rep PF01851.17 EAQ90419.1 - 3.9e-09 36.2 1.4 0.007 16.5 0.0 4.6 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Apc1 PF12859.2 EAQ90419.1 - 0.0077 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 Clathrin PF00637.15 EAQ90420.1 - 1.5e-20 73.2 0.7 9.5e-20 70.6 0.1 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EAQ90420.1 - 2.1e-06 27.3 0.6 0.0049 16.7 0.1 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat Vps39_1 PF10366.4 EAQ90420.1 - 0.0085 16.0 0.3 0.05 13.6 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CENP-B_dimeris PF09026.5 EAQ90420.1 - 0.61 10.3 14.2 1.5 9.0 9.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 EAQ90420.1 - 1 9.1 7.4 2.1 8.1 5.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 EAQ90420.1 - 1.1 8.5 14.5 12 5.0 9.7 2.1 2 0 0 2 2 2 0 NOA36 protein BUD22 PF09073.5 EAQ90420.1 - 1.2 8.1 7.5 2.3 7.2 5.2 1.3 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 EAQ90420.1 - 1.5 8.3 11.7 3 7.3 8.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 EAQ90420.1 - 1.6 6.8 2.7 2.4 6.2 1.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EAQ90420.1 - 2.7 5.9 6.5 4.2 5.2 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EAQ90420.1 - 8.6 3.9 11.3 13 3.4 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Daxx PF03344.10 EAQ90420.1 - 9.2 4.6 11.7 19 3.5 8.1 1.5 1 0 0 1 1 1 0 Daxx Family GST_C PF00043.20 EAQ90421.1 - 3.6e-13 49.2 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAQ90421.1 - 1.6e-10 40.9 0.0 8.8e-10 38.6 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAQ90421.1 - 4e-10 39.4 0.0 6.6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ90421.1 - 7.3e-08 32.8 0.0 1.2e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAQ90421.1 - 5.4e-06 26.5 0.0 9.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ90421.1 - 0.00026 20.9 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2997 PF11211.3 EAQ90421.1 - 0.022 14.1 0.1 0.044 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) RVT_1 PF00078.22 EAQ90422.1 - 1e-29 103.4 0.0 1.7e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GCR1_C PF12550.3 EAQ90423.1 - 3.5e-20 71.6 1.2 3.5e-20 71.6 0.8 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes ATG16 PF08614.6 EAQ90429.1 - 1.6e-05 24.7 9.7 3.9e-05 23.5 6.8 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EAQ90429.1 - 9.6e-05 21.0 1.9 9.6e-05 21.0 1.3 1.4 2 0 0 2 2 2 1 AAA domain zf-CCHC PF00098.18 EAQ90429.1 - 0.0015 18.3 0.1 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle IncA PF04156.9 EAQ90429.1 - 0.0018 17.8 2.7 0.0034 17.0 1.6 1.7 2 0 0 2 2 2 1 IncA protein HAP1_N PF04849.8 EAQ90429.1 - 0.0046 15.9 1.1 0.0087 15.0 0.7 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region SlyX PF04102.7 EAQ90429.1 - 0.013 15.8 5.0 0.083 13.2 0.2 2.8 1 1 1 2 2 2 0 SlyX Retrotrans_gag PF03732.12 EAQ90429.1 - 0.016 15.2 1.0 0.11 12.5 0.1 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein TMF_DNA_bd PF12329.3 EAQ90429.1 - 0.022 14.5 12.1 0.022 14.5 1.2 3.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EAQ90429.1 - 0.024 13.8 0.6 0.04 13.1 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EAQ90429.1 - 0.027 13.1 2.6 0.051 12.2 1.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein BRE1 PF08647.6 EAQ90429.1 - 0.077 12.9 4.1 0.18 11.7 2.9 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Tropomyosin PF00261.15 EAQ90429.1 - 0.1 11.6 7.1 0.18 10.9 5.0 1.3 1 0 0 1 1 1 0 Tropomyosin Uds1 PF15456.1 EAQ90429.1 - 0.19 11.7 12.3 3.5 7.6 0.3 4.0 3 1 1 4 4 3 0 Up-regulated During Septation Phage_GP20 PF06810.6 EAQ90429.1 - 0.2 11.1 2.5 0.33 10.4 0.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.10 EAQ90429.1 - 0.25 10.8 2.6 0.58 9.6 0.2 2.6 1 1 1 2 2 2 0 Septum formation initiator Nup54 PF13874.1 EAQ90429.1 - 1.4 8.5 8.5 0.29 10.8 2.1 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2894 PF11445.3 EAQ90429.1 - 2.3 8.4 8.4 0.4 10.9 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF4200 PF13863.1 EAQ90429.1 - 2.8 7.8 7.6 1.5 8.7 3.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) RVT_1 PF00078.22 EAQ90430.1 - 2.4e-20 72.7 0.0 5.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ90430.1 - 1.6e-13 50.8 0.2 5.4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ90430.1 - 2.9e-09 36.4 2.4 6.8e-09 35.2 1.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IN_DBD_C PF00552.16 EAQ90430.1 - 0.016 14.6 2.2 0.069 12.6 0.2 2.6 2 0 0 2 2 2 0 Integrase DNA binding domain PSI_PSAK PF01241.13 EAQ90431.1 - 0.015 15.2 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem I psaG / psaK HpcH_HpaI PF03328.9 EAQ90434.1 - 1.9e-29 102.1 0.1 2.6e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ADH_zinc_N PF00107.21 EAQ90435.1 - 1.3e-11 44.1 0.0 2.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ90435.1 - 2.2e-05 24.1 0.1 0.00026 20.6 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EAQ90436.1 - 0.0002 21.1 8.7 0.00031 20.5 6.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EAQ90439.1 - 3.2e-73 246.3 0.1 6e-73 245.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ90439.1 - 2.5e-54 184.7 0.0 4.3e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAQ90439.1 - 2.1e-41 142.0 1.1 3.7e-41 141.2 0.8 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EAQ90439.1 - 2.3e-33 114.5 0.0 5e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EAQ90439.1 - 7.8e-06 25.0 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Condensation PF00668.15 EAQ90441.1 - 5.6e-26 91.0 0.0 8.8e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EAQ90441.1 - 5.9e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EAQ90442.1 - 7.5e-35 120.1 0.0 9.3e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EAQ90443.1 - 3.4e-16 58.9 0.0 1.4e-15 56.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EAQ90443.1 - 1e-11 43.9 0.1 1.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EAQ90443.1 - 2.4e-10 40.2 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ90443.1 - 7.6e-09 35.8 0.2 1.7e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding PP-binding PF00550.20 EAQ90443.1 - 5.2e-08 33.0 0.0 1.7e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EAQ90443.1 - 0.00046 20.1 0.1 0.00046 20.1 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase DapB_N PF01113.15 EAQ90443.1 - 0.0054 16.6 0.3 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EAQ90443.1 - 0.006 16.2 0.0 0.006 16.2 0.0 2.6 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.10 EAQ90443.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EAQ90443.1 - 0.085 11.5 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BTB PF00651.26 EAQ90444.1 - 1.8e-12 47.2 0.0 3.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain FCD PF07729.7 EAQ90445.1 - 0.025 14.8 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 FCD domain FTA2 PF13095.1 EAQ90445.1 - 0.043 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SSP160 PF06933.6 EAQ90446.1 - 1.3 6.9 9.1 1.9 6.3 6.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Exo_endo_phos_2 PF14529.1 EAQ90447.1 - 2.6e-21 75.4 0.0 5.4e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EAQ90447.1 - 4.8e-13 48.9 0.0 1e-10 41.3 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EAQ90447.1 - 1e-09 38.7 0.0 2.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HET PF06985.6 EAQ90448.1 - 3.3e-22 79.1 0.0 7.1e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DIM PF08194.7 EAQ90449.1 - 0.02 14.8 0.4 0.09 12.7 0.1 2.1 2 0 0 2 2 2 0 DIM protein NACHT PF05729.7 EAQ90450.1 - 2.5e-09 37.0 0.0 7.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Zn_clus PF00172.13 EAQ90450.1 - 1.5e-06 27.9 11.9 2.5e-06 27.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.1 EAQ90450.1 - 8.9e-06 25.8 0.1 3.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAQ90450.1 - 0.00055 19.9 1.6 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAQ90450.1 - 0.0018 19.0 0.0 0.0082 16.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAQ90450.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EAQ90450.1 - 0.028 14.7 0.1 0.19 12.0 0.0 2.4 2 1 1 3 3 3 0 ABC transporter AAA_18 PF13238.1 EAQ90450.1 - 0.028 14.7 0.3 0.12 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EAQ90450.1 - 0.037 14.3 6.4 0.36 11.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAQ90450.1 - 0.054 13.0 0.4 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.2 EAQ90451.1 - 4.8e-16 59.3 0.2 2.3e-15 57.1 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ90451.1 - 9.8e-12 44.8 0.0 7.7e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EAQ90451.1 - 2e-07 29.9 0.0 2.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EAQ90451.1 - 1.3e-06 27.7 0.0 5.1e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EAQ90451.1 - 7.6e-06 25.6 0.3 0.00019 21.1 0.0 2.9 2 2 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 EAQ90451.1 - 0.0023 16.5 0.0 0.0067 14.9 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EAQ90451.1 - 0.035 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 EAQ90451.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 EAQ90451.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.3 EAQ90451.1 - 0.16 10.9 0.0 0.35 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) GCFC PF07842.7 EAQ90453.1 - 1.9e-84 283.2 3.1 1.9e-84 283.2 2.2 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EAQ90453.1 - 8.7e-18 64.3 14.3 8.7e-18 64.3 9.9 2.6 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EAQ90453.1 - 9.5e-15 54.1 1.2 2.4e-14 52.8 0.8 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EAQ90453.1 - 1.3e-08 34.5 3.9 2.1e-08 33.9 0.4 3.0 2 1 1 3 3 3 1 DExH-box splicing factor binding site Glyco_hydro_71 PF03659.9 EAQ90454.1 - 3.9e-33 114.4 0.2 4.7e-33 114.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 EF-hand_8 PF13833.1 EAQ90455.1 - 1.6e-16 59.5 5.2 7.8e-07 28.6 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EAQ90455.1 - 4.2e-16 58.8 1.3 4.4e-09 36.3 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EAQ90455.1 - 4.5e-14 50.6 5.3 5.9e-09 34.6 0.0 4.1 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 EAQ90455.1 - 4.1e-13 48.0 0.9 1.1e-08 34.1 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EAQ90455.1 - 1.9e-12 45.9 1.2 2.4e-07 29.7 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EAQ90455.1 - 2.1e-05 24.3 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EAQ90455.1 - 0.068 12.7 0.0 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Amidoligase_2 PF12224.3 EAQ90457.1 - 2e-18 66.9 0.1 2.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme HTH_21 PF13276.1 EAQ90457.1 - 0.03 14.3 3.3 0.63 10.1 1.5 2.6 2 0 0 2 2 2 0 HTH-like domain Herpes_UL32 PF06070.6 EAQ90458.1 - 0.26 9.6 21.9 0.28 9.5 15.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 EHN PF06441.7 EAQ90459.1 - 8.4e-30 102.9 0.7 1.6e-29 102.0 0.5 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EAQ90459.1 - 2.8e-06 27.3 0.1 6.8e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ90459.1 - 0.056 12.9 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA-synt_2b PF00587.20 EAQ90460.1 - 6.3e-15 55.1 0.1 1e-14 54.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) GntR PF00392.16 EAQ90461.1 - 0.024 14.0 0.1 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family BTB PF00651.26 EAQ90462.1 - 0.00023 21.1 0.0 0.00079 19.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain PELOTA_1 PF15608.1 EAQ90462.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain RVT_1 PF00078.22 EAQ90463.1 - 2.5e-38 131.6 0.0 4.7e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HGTP_anticodon PF03129.15 EAQ90463.1 - 6e-18 64.5 0.0 2.2e-17 62.7 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain MULE PF10551.4 EAQ90463.1 - 3.9e-15 55.7 0.0 3.6e-14 52.6 0.0 2.5 2 1 1 3 3 3 1 MULE transposase domain tRNA-synt_2b PF00587.20 EAQ90463.1 - 2.2e-14 53.4 0.0 1.3e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Exo_endo_phos_2 PF14529.1 EAQ90463.1 - 9.1e-14 51.0 0.0 2.4e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ90463.1 - 5.7e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transposase_mut PF00872.13 EAQ90463.1 - 0.00022 19.8 0.0 0.00042 18.9 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Lyase_aromatic PF00221.14 EAQ90464.1 - 4.7e-137 457.2 7.9 1.1e-135 452.7 5.5 2.0 1 1 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.20 EAQ90465.1 - 2.9e-27 95.6 0.4 3.6e-27 95.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ90465.1 - 1.1e-23 84.2 0.0 1.4e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ90465.1 - 5e-14 52.3 0.2 7e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAQ90465.1 - 0.0019 18.2 0.5 0.0025 17.8 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EAQ90465.1 - 0.0082 15.6 1.1 0.81 9.2 0.8 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.10 EAQ90465.1 - 0.044 12.6 0.3 0.058 12.2 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1372 PF07116.6 EAQ90465.1 - 0.068 13.1 0.1 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) THF_DHG_CYH_C PF02882.14 EAQ90465.1 - 0.074 12.1 0.1 0.15 11.1 0.0 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Mitofilin PF09731.4 EAQ90466.1 - 0.48 9.0 6.9 0.54 8.8 4.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAM196 PF15265.1 EAQ90466.1 - 4.9 6.2 13.5 6.2 5.9 9.4 1.1 1 0 0 1 1 1 0 FAM196 family Lipase_GDSL_2 PF13472.1 EAQ90467.1 - 2.1e-12 47.5 0.1 3.8e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ90467.1 - 6.5e-06 26.1 0.0 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase fn3 PF00041.16 EAQ90467.1 - 1.1e-05 25.5 0.1 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Lipase_GDSL_3 PF14606.1 EAQ90467.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Bac_luciferase PF00296.15 EAQ90468.1 - 4.7e-65 219.7 3.3 6e-65 219.3 2.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1024 PF06260.7 EAQ90468.1 - 0.032 14.3 0.3 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) Acyl-CoA_dh_2 PF08028.6 EAQ90469.1 - 6e-20 71.8 2.3 1.1e-19 71.0 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAQ90469.1 - 5.3e-06 26.9 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EAQ90469.1 - 0.0019 18.2 3.5 0.0033 17.5 0.2 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 EAQ90469.1 - 0.017 14.8 0.0 0.082 12.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) SAPS PF04499.10 EAQ90470.1 - 6.2e-197 654.9 0.0 5.7e-196 651.7 0.0 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein 3HCDH_N PF02737.13 EAQ90472.1 - 2.9e-52 176.9 0.7 4.1e-52 176.4 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EAQ90472.1 - 1.8e-33 114.8 0.0 3.5e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 EAQ90472.1 - 0.00025 20.1 0.1 0.00034 19.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EAQ90472.1 - 0.00027 20.8 0.1 0.00073 19.4 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EAQ90472.1 - 0.0016 18.1 1.0 0.0032 17.1 0.7 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EAQ90472.1 - 0.0055 15.6 0.3 0.0097 14.8 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EAQ90472.1 - 0.0056 16.1 0.2 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EAQ90472.1 - 0.0093 16.3 0.7 0.042 14.2 0.5 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EAQ90472.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 EAQ90472.1 - 0.033 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EAQ90472.1 - 0.034 13.2 0.3 0.13 11.4 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EAQ90472.1 - 0.09 12.8 0.7 0.14 12.2 0.5 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EAQ90472.1 - 0.11 12.5 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EAQ90472.1 - 0.13 12.6 0.1 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.8 EAQ90473.1 - 1.1e-27 96.9 0.0 1.5e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EAQ90473.1 - 2.4e-05 23.2 0.0 3.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EAQ90473.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3966 PF13110.1 EAQ90473.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) MFS_1 PF07690.11 EAQ90474.1 - 4.4e-33 114.4 39.0 6.4e-33 113.9 27.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Gly-rich_Ago1 PF12764.2 EAQ90474.1 - 0.013 16.0 1.5 0.013 16.0 1.1 2.2 2 0 0 2 2 2 0 Glycine-rich region of argonaut TMEM169 PF15052.1 EAQ90474.1 - 6.1 6.7 10.5 0.9 9.4 1.9 3.1 3 1 1 4 4 4 0 TMEM169 protein family SET PF00856.23 EAQ90475.1 - 0.022 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 SET domain PIF1 PF05970.9 EAQ90476.1 - 1.6e-08 33.9 0.0 3.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Ank_2 PF12796.2 EAQ90477.1 - 9.4e-52 173.3 2.9 1.4e-19 70.2 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ90477.1 - 1.3e-43 144.6 9.6 1e-06 28.2 0.1 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EAQ90477.1 - 1.1e-30 105.4 0.7 5e-06 26.8 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ90477.1 - 4.5e-23 80.7 4.4 2.3e-05 24.4 0.2 6.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ90477.1 - 2.1e-17 61.4 2.3 0.1 12.8 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat PNP_UDP_1 PF01048.15 EAQ90477.1 - 7.8e-07 28.3 0.1 2.9e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Helitron_like_N PF14214.1 EAQ90479.1 - 0.0078 15.9 0.2 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SH3BGR PF04908.10 EAQ90479.1 - 0.099 12.5 0.4 0.48 10.3 0.0 2.2 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein AT_hook PF02178.14 EAQ90479.1 - 9.6 6.2 17.0 3.3 7.6 3.6 3.6 2 1 1 3 3 3 0 AT hook motif Glyco_transf_28 PF03033.15 EAQ90480.1 - 0.0094 15.7 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Polysacc_deac_1 PF01522.16 EAQ90481.1 - 7.3e-17 61.1 0.2 1.7e-16 59.9 0.1 1.6 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EAQ90481.1 - 0.011 14.7 0.0 0.014 14.2 0.0 1.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Fungal_trans PF04082.13 EAQ90482.1 - 5.7e-30 104.0 0.0 1.1e-29 103.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ90482.1 - 6.2e-10 38.8 12.6 1.2e-09 37.9 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4106 PF13388.1 EAQ90482.1 - 1.9 7.3 7.2 4 6.2 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Peptidase_M41 PF01434.13 EAQ90483.1 - 1.9e-74 249.7 0.0 3e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EAQ90483.1 - 1.9e-42 144.5 0.0 4e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EAQ90483.1 - 1.1e-09 38.4 0.0 1.1e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EAQ90483.1 - 0.0016 18.6 0.0 0.07 13.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ90483.1 - 0.003 17.5 0.3 0.11 12.4 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EAQ90483.1 - 0.0044 17.8 0.1 0.087 13.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ90483.1 - 0.0051 16.5 0.2 0.029 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAQ90483.1 - 0.0071 15.4 0.0 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ90483.1 - 0.0082 15.8 1.6 0.014 15.1 0.3 2.0 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EAQ90483.1 - 0.0098 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EAQ90483.1 - 0.011 15.1 0.1 0.035 13.5 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.1 EAQ90483.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EAQ90483.1 - 0.031 14.1 0.7 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EAQ90483.1 - 0.057 12.8 2.8 0.13 11.6 0.1 2.7 2 1 1 3 3 3 0 AAA domain Plasmodium_Vir PF05795.6 EAQ90483.1 - 0.13 11.4 0.7 0.2 10.8 0.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.9 EAQ90483.1 - 1.5 6.7 5.5 1.9 6.3 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein HCO3_cotransp PF00955.16 EAQ90484.1 - 2.9e-49 168.0 18.6 6.7e-24 84.4 3.7 3.0 2 1 1 3 3 3 3 HCO3- transporter family TraG-D_C PF12696.2 EAQ90486.1 - 0.086 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Homeobox PF00046.24 EAQ90487.1 - 1.7e-14 53.1 2.1 3.3e-14 52.2 1.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAQ90487.1 - 0.0022 17.6 0.1 0.0054 16.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain TIMELESS PF04821.9 EAQ90489.1 - 4.1e-94 314.7 0.5 1.1e-93 313.4 0.0 1.9 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 EAQ90489.1 - 4e-33 115.1 0.1 4e-33 115.1 0.1 4.2 3 1 0 4 4 4 2 Timeless protein C terminal region MFS_1 PF07690.11 EAQ90490.1 - 4.3e-43 147.3 43.4 4.3e-43 147.3 30.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ90490.1 - 2e-15 56.3 11.3 2e-15 56.3 7.8 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EAQ90490.1 - 5.2e-10 38.1 18.6 7.8e-10 37.5 12.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.2 EAQ90491.1 - 4.8e-60 199.9 2.1 4.2e-19 68.6 1.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ90491.1 - 1.2e-45 151.1 17.3 2.7e-08 33.2 0.5 12.5 12 0 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.1 EAQ90491.1 - 4e-35 116.3 4.8 5.4e-05 23.0 0.1 12.8 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.1 EAQ90491.1 - 3.5e-31 106.9 5.4 8.1e-08 32.5 0.4 10.6 7 3 4 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ90491.1 - 4.9e-26 90.1 11.6 9.8e-09 35.1 0.9 8.8 4 2 6 10 10 10 6 Ankyrin repeats (many copies) NACHT PF05729.7 EAQ90491.1 - 5.7e-11 42.3 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ90491.1 - 3e-05 24.0 1.3 6.2e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ90491.1 - 0.027 14.6 0.4 0.36 10.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EAQ90491.1 - 0.063 13.1 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAQ90491.1 - 0.17 10.7 0.0 0.6 8.9 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Syntaxin_2 PF14523.1 EAQ90491.1 - 0.18 11.8 1.0 1.8 8.6 0.1 2.7 2 1 0 2 2 2 0 Syntaxin-like protein GFO_IDH_MocA PF01408.17 EAQ90492.1 - 2.1e-09 37.9 0.6 8.9e-09 35.9 0.4 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EAQ90492.1 - 0.026 14.9 0.0 0.05 13.9 0.0 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DHDPS PF00701.17 EAQ90493.1 - 2.9e-10 39.2 0.0 4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DAO PF01266.19 EAQ90494.1 - 4.2e-57 193.6 4.1 1.6e-56 191.7 2.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ90494.1 - 5.8e-05 23.0 0.5 0.00014 21.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAQ90494.1 - 8.4e-05 22.9 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EAQ90494.1 - 0.00065 18.9 0.1 0.37 9.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.9 EAQ90494.1 - 0.0023 16.6 0.2 0.0037 15.9 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EAQ90494.1 - 0.0023 17.8 0.3 1.3 8.9 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ90494.1 - 0.005 15.7 0.5 2.3 6.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Mqo PF06039.10 EAQ90494.1 - 0.045 11.9 0.0 0.53 8.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 EAQ90494.1 - 0.048 12.7 0.1 0.083 11.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GSHPx PF00255.14 EAQ90495.1 - 7.6e-23 79.9 0.0 1e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 EAQ90495.1 - 0.0028 17.7 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Fungal_trans_2 PF11951.3 EAQ90497.1 - 2.1e-34 118.7 0.3 1.4e-28 99.6 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ90497.1 - 1.1e-06 28.4 6.9 1.1e-06 28.4 4.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2638 PF10937.3 EAQ90497.1 - 1.8 9.6 13.2 0.82 10.7 0.3 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2638) Peptidase_S3 PF00944.14 EAQ90498.1 - 0.054 12.9 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_S7 PF00949.16 EAQ90498.1 - 0.19 11.1 0.9 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Nop16 PF09420.5 EAQ90499.1 - 7.4e-28 97.7 0.7 1.2e-27 97.0 0.5 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 PIF1 PF05970.9 EAQ90501.1 - 1e-16 60.8 0.0 1.2e-12 47.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ90501.1 - 2.9e-05 23.7 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ90501.1 - 0.00016 21.7 0.0 0.00071 19.6 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ90501.1 - 0.0003 18.6 0.0 0.00073 17.4 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 EAQ90501.1 - 0.0004 20.0 0.2 0.00098 18.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EAQ90501.1 - 0.14 11.6 1.7 13 5.2 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EAQ90501.1 - 0.17 12.0 0.0 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RVT_1 PF00078.22 EAQ90502.1 - 1.8e-08 33.9 0.0 4.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FCH PF00611.18 EAQ90503.1 - 7.4e-17 61.3 0.2 5.6e-16 58.5 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EAQ90503.1 - 2e-14 53.0 0.0 4.4e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 EAQ90503.1 - 1.3e-13 50.8 0.2 4e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Ribosomal_S13 PF00416.17 EAQ90506.1 - 2.8e-17 63.1 0.0 3.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Methyltransf_32 PF13679.1 EAQ90507.1 - 1e-20 73.8 0.1 8.6e-20 70.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Death PF00531.17 EAQ90507.1 - 0.15 11.8 0.4 0.46 10.2 0.0 2.0 2 1 0 2 2 2 0 Death domain ACT_7 PF13840.1 EAQ90508.1 - 4.3e-19 67.8 0.1 8.3e-19 66.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain UPF0029 PF01205.14 EAQ90509.1 - 1.3e-29 102.1 0.0 1.9e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EAQ90509.1 - 5.6e-09 35.9 0.0 9.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain AIG2 PF06094.7 EAQ90510.1 - 1.2e-20 73.8 0.1 1.5e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family Chitin_bind_3 PF03067.10 EAQ90512.1 - 2.4e-05 24.6 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 EAQ90512.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAT PF02259.18 EAQ90513.1 - 1.3e-78 264.5 3.5 2.4e-78 263.5 2.4 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EAQ90513.1 - 1e-23 84.0 0.1 7.7e-23 81.1 0.0 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EAQ90513.1 - 7.9e-10 38.0 0.1 2.3e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 FATC domain Glycolytic PF00274.14 EAQ90513.1 - 0.07 11.5 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I AMP-binding PF00501.23 EAQ90514.1 - 9.3e-31 106.6 0.0 1.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Apc3 PF12895.2 EAQ90515.1 - 1e-23 83.2 22.9 7.6e-21 74.0 0.7 6.0 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EAQ90515.1 - 2.9e-22 76.7 29.7 0.0015 18.2 0.7 10.7 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ90515.1 - 7.6e-21 73.5 32.1 7.2e-07 28.7 0.1 7.9 4 3 3 8 8 8 8 TPR repeat TPR_19 PF14559.1 EAQ90515.1 - 2.1e-20 72.7 25.8 6.5e-06 26.3 0.0 8.7 5 3 2 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ90515.1 - 3.2e-19 67.6 20.4 0.00034 20.0 0.9 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ90515.1 - 5.1e-16 58.3 33.8 4e-08 33.0 0.5 8.6 5 4 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ90515.1 - 9.7e-15 53.7 33.4 0.028 15.0 0.2 10.5 5 2 6 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ90515.1 - 5.1e-14 52.4 33.0 0.0002 21.9 2.3 8.4 6 3 3 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ90515.1 - 4.6e-10 38.5 8.3 0.0059 16.2 0.4 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EAQ90515.1 - 0.00017 20.7 12.4 0.11 11.5 0.6 4.8 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ90515.1 - 0.00034 20.4 17.8 0.16 11.9 0.1 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ90515.1 - 0.00042 19.9 22.7 6.8 6.7 0.0 8.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90515.1 - 0.01 16.2 19.2 0.89 10.1 0.4 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.2 EAQ90515.1 - 0.012 15.6 0.6 0.044 13.8 0.1 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_17 PF13431.1 EAQ90515.1 - 0.15 12.3 12.0 1e+02 3.4 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Alk_phosphatase PF00245.15 EAQ90516.1 - 1e-62 212.1 0.0 1.9e-62 211.3 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EAQ90516.1 - 3e-07 30.0 0.7 1.8e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAQ90516.1 - 4.3e-06 26.1 0.1 9.6e-06 24.9 0.1 1.5 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EAQ90516.1 - 0.0027 16.1 0.1 0.0042 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 EAQ90516.1 - 0.027 13.2 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FTA4 PF13093.1 EAQ90516.1 - 0.23 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CutC PF03932.9 EAQ90518.1 - 1.9e-12 46.8 2.7 4.7e-08 32.5 0.0 3.9 3 1 0 3 3 3 3 CutC family PGP_phosphatase PF09419.5 EAQ90520.1 - 7.9e-67 223.8 0.0 1.1e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EAQ90520.1 - 0.00036 20.1 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like ORC2 PF04084.9 EAQ90521.1 - 2.1e-78 263.4 0.0 2.7e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DEAD PF00270.24 EAQ90522.1 - 4.2e-47 159.7 0.0 1.6e-45 154.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ90522.1 - 2.2e-29 101.1 0.0 4.2e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ90522.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EAQ90522.1 - 0.047 12.1 0.0 0.14 10.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EAQ90522.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit WD40 PF00400.27 EAQ90523.1 - 2e-26 90.8 1.8 1.8e-07 30.7 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EAQ90523.1 - 0.031 12.4 0.0 0.31 9.1 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 gpW PF02831.10 EAQ90523.1 - 0.093 12.3 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 gpW Pap_E4 PF02711.9 EAQ90523.1 - 2.7 8.8 11.8 8.4 7.2 1.8 3.2 2 1 0 2 2 2 0 E4 protein Peptidase_C48 PF02902.14 EAQ90524.1 - 5.2e-29 101.4 0.0 7.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ndufs5 PF10200.4 EAQ90526.1 - 0.00016 21.6 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.12 EAQ90526.1 - 0.013 15.5 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 EAQ90526.1 - 0.014 15.2 0.3 0.022 14.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 EAQ90526.1 - 0.018 14.9 1.2 0.036 13.9 0.8 1.6 1 0 0 1 1 1 0 CHCH domain DUF3128 PF11326.3 EAQ90526.1 - 0.096 12.8 1.5 0.23 11.5 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Pkinase PF00069.20 EAQ90527.1 - 2.9e-07 29.9 0.0 4.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EAQ90527.1 - 0.0019 17.7 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EAQ90527.1 - 0.08 11.9 0.0 0.53 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Pol_alpha_B_N PF08418.5 EAQ90528.1 - 6.7 6.1 6.6 8.8 5.7 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Sec39 PF08314.6 EAQ90529.1 - 1.2e-220 734.1 0.0 4e-118 395.3 0.0 2.0 1 1 1 2 2 2 2 Secretory pathway protein Sec39 DIOX_N PF14226.1 EAQ90531.1 - 3.9e-13 49.9 0.4 1.2e-07 32.2 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal GCD14 PF08704.5 EAQ90532.1 - 4.5e-62 209.7 0.0 1.3e-46 159.1 0.0 2.5 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EAQ90532.1 - 0.12 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MS_channel PF00924.13 EAQ90533.1 - 1.6e-21 76.6 2.7 2.8e-21 75.8 1.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel HemY_N PF07219.8 EAQ90533.1 - 3.4 7.2 8.2 0.92 9.0 1.2 2.7 2 0 0 2 2 2 0 HemY protein N-terminus Glyco_hydro_31 PF01055.21 EAQ90534.1 - 3.4e-152 507.3 2.2 4.4e-152 506.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAQ90534.1 - 9.8e-24 82.9 0.2 3.1e-23 81.4 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 EAQ90535.1 - 2e-53 179.8 0.0 2.2e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EAQ90535.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ FLILHELTA PF10306.4 EAQ90536.1 - 1.4e-30 105.1 0.0 2.2e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DNA_ligase_A_M PF01068.16 EAQ90537.1 - 5.3e-15 55.3 0.1 3.9e-13 49.2 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAQ90537.1 - 1.5e-09 37.8 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus Transp_cyt_pur PF02133.10 EAQ90538.1 - 2.4e-22 79.0 12.6 2.9e-22 78.8 8.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YuiB PF14068.1 EAQ90538.1 - 0.0095 16.2 0.1 0.028 14.7 0.1 1.8 1 0 0 1 1 1 1 Putative membrane protein Bacteriocin_IId PF09221.5 EAQ90538.1 - 4 7.4 9.7 0.29 11.0 1.1 2.5 1 1 1 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Glyoxalase PF00903.20 EAQ90539.1 - 1.7e-08 34.4 0.1 3.6e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EAQ90539.1 - 2.9e-06 27.8 0.1 2.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase-like domain Peptidase_M50B PF13398.1 EAQ90540.1 - 4.3e-58 195.9 17.9 5.7e-58 195.6 12.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like UCR_Fe-S_N PF10399.4 EAQ90540.1 - 0.096 11.8 0.2 0.096 11.8 0.1 3.3 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_M50 PF02163.17 EAQ90540.1 - 0.11 11.3 6.0 0.035 13.0 1.5 2.3 2 1 0 2 2 2 0 Peptidase family M50 Na_Pi_cotrans PF02690.10 EAQ90540.1 - 0.65 9.7 7.7 0.089 12.5 1.5 2.3 2 1 0 2 2 2 0 Na+/Pi-cotransporter YlaC PF10777.4 EAQ90540.1 - 3.4 7.2 4.9 0.58 9.7 0.2 1.8 2 0 0 2 2 2 0 Inner membrane protein YlaC CAF1A PF12253.3 EAQ90541.1 - 1.1e-22 79.9 2.6 1.1e-22 79.9 1.8 3.3 2 1 1 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EAQ90541.1 - 1.7e-10 40.6 55.5 1.7e-10 40.6 38.5 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glucokinase PF02685.11 EAQ90542.1 - 0.0063 15.3 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 Glucokinase SPX PF03105.14 EAQ90543.1 - 5.5e-58 196.9 0.0 8.7e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 SPX domain EXS PF03124.9 EAQ90543.1 - 1.8e-39 135.7 20.3 7.8e-21 74.4 4.1 2.1 1 1 1 2 2 2 2 EXS family DUF883 PF05957.8 EAQ90543.1 - 0.12 12.7 1.3 0.35 11.2 0.9 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Peptidase_M18 PF02127.10 EAQ90544.1 - 1.7e-125 418.9 0.0 2e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.1 EAQ90544.1 - 0.077 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family PAF-AH_p_II PF03403.8 EAQ90545.1 - 6.1e-38 130.1 0.0 4.9e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EAQ90545.1 - 9.8e-10 38.3 0.3 3.2e-09 36.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EAQ90545.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EAQ90545.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 EAQ90545.1 - 0.028 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase LSM PF01423.17 EAQ90547.1 - 4.8e-15 54.8 0.3 6.7e-15 54.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain FliT PF05400.8 EAQ90548.1 - 2.2 8.7 9.2 0.15 12.4 1.6 2.3 2 0 0 2 2 2 0 Flagellar protein FliT UQ_con PF00179.21 EAQ90549.1 - 6.9e-51 171.3 0.0 7.7e-51 171.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_11 PF13414.1 EAQ90550.1 - 1.5e-09 37.3 0.1 3e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EAQ90550.1 - 2.2e-05 24.0 1.1 1.2 9.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ90550.1 - 5.4e-05 22.6 0.0 0.13 11.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.26 EAQ90550.1 - 8.1e-05 22.3 0.1 0.00035 20.3 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.1 EAQ90550.1 - 0.12 12.3 0.1 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1996 PF09362.5 EAQ90551.1 - 4.1e-59 200.0 0.7 1.7e-52 178.4 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) DUF572 PF04502.8 EAQ90554.1 - 3.6e-56 190.7 11.7 2.6e-55 187.9 8.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF1237 PF06824.6 EAQ90554.1 - 0.07 11.7 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) Mito_fiss_reg PF05308.6 EAQ90554.1 - 0.87 8.9 4.1 0.14 11.5 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Spc97_Spc98 PF04130.8 EAQ90555.1 - 6.3e-71 239.3 0.1 8.3e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EAQ90555.1 - 0.19 9.7 0.0 0.27 9.2 0.0 1.2 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 EAQ90556.1 - 2.4e-112 375.1 14.9 2.9e-112 374.8 10.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 EAQ90557.1 - 1.7e-19 68.8 8.3 2e-05 24.2 0.0 6.8 5 2 0 5 5 5 4 WD domain, G-beta repeat PQQ PF01011.16 EAQ90557.1 - 0.28 10.7 6.0 3.2 7.4 0.1 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.1 EAQ90557.1 - 2.2 8.6 12.5 0.52 10.6 0.9 4.6 4 1 1 5 5 5 0 PQQ-like domain Serglycin PF04360.7 EAQ90557.1 - 2.2 7.9 9.7 4 7.1 6.8 1.4 1 0 0 1 1 1 0 Serglycin Zn_clus PF00172.13 EAQ90558.1 - 4e-07 29.8 8.7 6.5e-07 29.1 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.9 EAQ90562.1 - 5.7e-17 61.0 4.0 3.7e-13 48.8 1.2 2.4 2 0 0 2 2 2 2 PQ loop repeat MTHFR PF02219.12 EAQ90564.1 - 7.1e-101 337.0 0.0 8.8e-101 336.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IF4E PF01652.13 EAQ90565.1 - 4e-52 176.0 0.0 6.2e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UCH PF00443.24 EAQ90566.1 - 2.3e-25 89.2 0.0 3.3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAQ90566.1 - 3.3e-12 46.3 0.1 6.1e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EAQ90566.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EAQ90567.1 - 1.7e-66 217.8 16.5 1.1e-08 34.5 0.0 11.7 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EAQ90567.1 - 3.4e-44 149.9 0.1 5.5e-44 149.2 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EAQ90567.1 - 5.5e-07 28.1 1.9 0.0019 16.4 0.0 4.2 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ90567.1 - 2.2e-05 23.4 5.7 0.63 8.7 0.0 4.8 4 1 1 5 5 5 3 Nup133 N terminal like Lamp PF01299.12 EAQ90568.1 - 0.37 9.9 1.9 0.53 9.3 1.3 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) CENP-S PF15630.1 EAQ90569.1 - 2.8e-35 120.3 0.1 4.7e-35 119.6 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EAQ90569.1 - 0.00048 19.8 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EAQ90569.1 - 0.00085 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 EAQ90569.1 - 0.0024 17.6 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EAQ90569.1 - 0.062 13.4 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EAQ90569.1 - 0.085 12.8 0.1 0.51 10.3 0.0 2.1 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.10 EAQ90569.1 - 0.1 12.4 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PGA2 PF07543.7 EAQ90570.1 - 6e-29 100.6 8.5 8.8e-29 100.0 5.9 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 Drc1-Sld2 PF11719.3 EAQ90570.1 - 0.007 15.5 1.1 0.0091 15.1 0.7 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein ELM2 PF01448.19 EAQ90570.1 - 0.14 12.7 1.8 0.66 10.6 1.2 2.1 1 1 0 1 1 1 0 ELM2 domain BTV_NS2 PF04514.7 EAQ90570.1 - 3.3 6.4 7.7 4.8 5.9 5.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PPTA PF01239.17 EAQ90571.1 - 2.6e-40 134.1 9.0 1.4e-07 30.5 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.1 EAQ90571.1 - 0.0079 15.9 2.3 0.088 12.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ90571.1 - 0.015 15.6 2.5 1.4 9.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat VWA_3 PF13768.1 EAQ90571.1 - 0.045 13.4 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain UPF0149 PF03695.8 EAQ90571.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) TPR_14 PF13428.1 EAQ90571.1 - 0.08 13.6 1.0 27 5.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ90571.1 - 2.1 8.4 4.6 3.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EAQ90572.1 - 1.3e-18 66.8 0.0 2.8e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EAQ90572.1 - 3.5e-10 39.9 0.0 7.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EAQ90572.1 - 0.0076 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Collagen PF01391.13 EAQ90572.1 - 1.1 8.8 11.0 0.024 14.1 1.9 2.1 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) ABM PF03992.11 EAQ90573.1 - 0.52 10.3 5.2 0.89 9.6 3.6 1.5 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Ribosomal_L38e PF01781.13 EAQ90574.1 - 3.4e-34 116.4 1.3 4.1e-34 116.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.4 EAQ90574.1 - 0.048 13.3 0.1 0.051 13.2 0.1 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain FAM196 PF15265.1 EAQ90574.1 - 4.4 6.4 9.5 1.1 8.4 2.1 1.9 1 1 1 2 2 2 0 FAM196 family Peptidase_M48 PF01435.13 EAQ90576.1 - 5.5e-11 42.4 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Glyco_hydro_3 PF00933.16 EAQ90578.1 - 2e-62 210.8 0.0 3e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ90578.1 - 3.3e-36 124.9 0.0 4.2e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ90578.1 - 5.7e-23 80.6 0.4 1.2e-22 79.6 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.20 EAQ90579.1 - 7.2e-39 132.6 0.0 1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EAQ90579.1 - 0.00026 20.9 0.1 0.00032 20.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ90579.1 - 0.0012 18.6 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ90579.1 - 0.0021 17.6 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.17 EAQ90579.1 - 0.004 16.9 1.3 0.014 15.1 0.9 1.8 1 1 0 1 1 1 1 Cutinase DUF676 PF05057.9 EAQ90579.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.7 EAQ90579.1 - 0.0079 15.7 0.1 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF2974 PF11187.3 EAQ90579.1 - 0.022 14.1 1.0 0.45 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF1069 PF06370.6 EAQ90579.1 - 0.12 11.7 0.5 0.26 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Flg_new PF09479.5 EAQ90579.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Esterase PF00756.15 EAQ90579.1 - 0.16 11.3 0.2 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Putative esterase GAS2 PF02187.12 EAQ90580.1 - 5.1e-05 22.9 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fungal_trans PF04082.13 EAQ90581.1 - 4.4e-35 120.8 0.6 7.3e-35 120.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ90581.1 - 2.3e-07 30.5 8.6 4.3e-07 29.7 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.14 EAQ90583.1 - 3.5e-74 244.7 61.5 3.9e-20 71.5 7.7 4.6 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.18 EAQ90583.1 - 6.2e-23 81.4 0.0 1.5e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Peroxidase PAP2 PF01569.16 EAQ90585.1 - 2.9e-16 59.3 3.9 5.6e-16 58.3 2.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily RWD PF05773.17 EAQ90586.1 - 8.2e-23 80.4 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EAQ90586.1 - 2.3e-21 75.4 31.4 1.8e-14 53.3 2.2 3.9 3 1 1 4 4 4 3 IBR domain zf-RING_UBOX PF13445.1 EAQ90586.1 - 0.0036 16.9 2.1 0.0036 16.9 1.4 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EAQ90586.1 - 0.0097 15.5 4.2 0.0097 15.5 2.9 4.4 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ90586.1 - 0.014 15.3 3.1 0.014 15.3 2.2 4.4 3 2 1 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EAQ90586.1 - 2.4 8.0 32.8 0.03 14.1 2.9 3.7 2 1 1 3 3 3 0 Ring finger domain NDT80_PhoG PF05224.7 EAQ90588.1 - 2.7e-39 135.0 0.3 6.2e-39 133.9 0.0 1.7 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF3402 PF11882.3 EAQ90589.1 - 7.6e-150 499.5 0.0 1.1e-149 498.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EAQ90589.1 - 9.7e-57 192.0 0.0 1.1e-27 96.7 0.0 2.7 1 1 1 2 2 2 2 N1221-like protein DUF2011 PF09428.5 EAQ90589.1 - 1.8e-07 31.1 0.0 3.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) PPP4R2 PF09184.6 EAQ90589.1 - 2.7 7.4 8.9 6 6.3 6.2 1.5 1 0 0 1 1 1 0 PPP4R2 Ndc1_Nup PF09531.5 EAQ90590.1 - 2.4 6.4 9.5 1.4 7.2 3.7 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pox_F11 PF04943.7 EAQ90591.1 - 0.041 12.7 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein DUF2823 PF11034.3 EAQ90592.1 - 8.2e-35 118.7 10.6 9.1e-35 118.6 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) MT0933_antitox PF14013.1 EAQ90592.1 - 0.21 11.7 8.3 5.4 7.2 3.9 2.2 1 1 1 2 2 2 0 MT0933-like antitoxin protein CTDII PF01556.13 EAQ90595.1 - 7.4e-17 61.0 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.26 EAQ90595.1 - 2.6e-14 52.7 1.4 4.5e-14 51.9 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Zn_clus PF00172.13 EAQ90596.1 - 3.9e-09 36.2 9.9 7.5e-09 35.3 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ90596.1 - 1.2e-05 24.1 0.1 1.8e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Init_tRNA_PT PF04179.7 EAQ90597.1 - 1.2e-115 387.0 0.0 1.4e-59 202.1 0.0 2.0 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 EAQ90598.1 - 8.4e-16 58.6 0.0 1.2e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ90598.1 - 5.1e-10 40.1 0.1 2.1e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ90598.1 - 7.9e-09 35.1 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EAQ90598.1 - 1.1e-05 25.1 0.0 0.0022 17.6 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.1 EAQ90598.1 - 0.065 13.1 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Baculo_p74 PF04583.7 EAQ90598.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Thioredoxin PF00085.15 EAQ90600.1 - 3.1e-64 213.1 0.0 1.1e-30 105.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EAQ90600.1 - 3.6e-25 88.4 2.0 9.7e-25 87.0 0.6 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EAQ90600.1 - 4e-21 75.3 0.2 1.4e-09 38.1 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EAQ90600.1 - 3.4e-14 52.6 0.3 4.2e-06 26.6 0.0 2.7 3 0 0 3 3 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EAQ90600.1 - 5.7e-13 48.8 0.0 2.9e-05 24.0 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EAQ90600.1 - 5.4e-07 29.3 0.1 0.038 13.6 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EAQ90600.1 - 2.5e-06 27.1 1.1 0.0093 15.5 0.1 2.5 1 1 1 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 EAQ90600.1 - 1.1e-05 25.3 0.0 0.0062 16.3 0.0 3.3 1 1 2 3 3 3 3 Thioredoxin-like domain ERp29_N PF07912.8 EAQ90600.1 - 1.3e-05 25.1 0.0 0.0053 16.6 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EAQ90600.1 - 4e-05 23.3 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 EAQ90600.1 - 4.8e-05 22.9 0.0 0.03 13.8 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_4 PF13462.1 EAQ90600.1 - 0.00017 21.6 1.3 0.14 12.1 0.0 3.6 3 2 1 4 4 4 1 Thioredoxin HyaE PF07449.6 EAQ90600.1 - 0.0021 17.9 0.0 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EAQ90600.1 - 0.023 14.7 0.7 8.1 6.5 0.0 3.0 2 2 0 2 2 2 0 Glutaredoxin DSBA PF01323.15 EAQ90600.1 - 0.058 12.9 2.7 27 4.2 0.0 3.9 3 1 1 4 4 4 0 DSBA-like thioredoxin domain AF0941-like PF14591.1 EAQ90600.1 - 0.066 13.2 0.4 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 AF0941-like Ribosomal_S14 PF00253.16 EAQ90601.1 - 1.2e-19 69.3 3.4 1.4e-19 69.2 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 EAQ90601.1 - 0.26 11.3 3.9 4.3 7.4 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase GTP_EFTU PF00009.22 EAQ90602.1 - 8e-60 201.5 0.1 1.1e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAQ90602.1 - 1.4e-23 82.9 0.0 2.6e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAQ90602.1 - 2.8e-15 56.1 2.4 2.8e-15 56.1 1.7 2.0 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAQ90602.1 - 2.7e-05 24.1 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EAQ90602.1 - 0.0013 18.2 0.3 0.0039 16.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EAQ90602.1 - 0.0041 17.6 0.0 0.0072 16.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EAQ90602.1 - 0.054 12.9 0.1 8.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EAQ90602.1 - 0.16 11.1 0.1 0.47 9.5 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Menin PF05053.8 EAQ90603.1 - 0.02 13.0 1.3 0.03 12.5 0.9 1.2 1 0 0 1 1 1 0 Menin NAD_kinase PF01513.16 EAQ90604.1 - 2.1e-69 233.4 0.0 3e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase PfkB PF00294.19 EAQ90605.1 - 1.3e-15 57.2 0.0 1.5e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF4611 PF15387.1 EAQ90606.1 - 5.7 7.1 10.2 7.2 6.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Saccharop_dh PF03435.13 EAQ90607.1 - 3.2e-131 437.8 0.0 3.8e-131 437.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EAQ90607.1 - 3.2e-05 24.0 0.3 6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EAQ90607.1 - 9.6e-05 22.4 0.2 0.0002 21.4 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EAQ90607.1 - 0.0012 18.2 0.2 0.045 13.1 0.0 2.8 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EAQ90607.1 - 0.083 12.9 0.2 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EAQ90607.1 - 0.086 13.3 0.1 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Las1 PF04031.8 EAQ90608.1 - 8e-61 204.2 0.0 1.3e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 EAQ90608.1 - 1.3e-12 47.7 0.5 1.3e-12 47.7 0.4 3.1 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily EF-hand_9 PF14658.1 EAQ90609.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain IF4E PF01652.13 EAQ90610.1 - 3.1e-38 130.8 0.3 4e-38 130.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EAQ90611.1 - 0.0014 18.8 1.1 0.0056 16.9 0.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) Cut8_N PF14482.1 EAQ90611.1 - 4.5 7.3 11.8 0.2 11.6 0.9 3.6 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Kinesin PF00225.18 EAQ90612.1 - 2.4e-104 348.6 0.0 3.3e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain PUL PF08324.6 EAQ90612.1 - 1.9e-36 125.2 0.0 2.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EAQ90612.1 - 3e-17 62.7 0.0 5.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EAQ90612.1 - 5.6e-13 48.4 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAQ90612.1 - 0.006 16.7 0.1 0.069 13.3 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EAQ90612.1 - 0.018 14.7 0.0 0.062 12.9 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_3 PF13192.1 EAQ90612.1 - 0.23 11.3 0.0 0.93 9.3 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain GDA1_CD39 PF01150.12 EAQ90613.1 - 3.4e-95 319.1 0.0 4.1e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_3 PF07726.6 EAQ90614.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 EAQ90615.1 - 2.1e-57 193.0 0.0 2.5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ90615.1 - 1.1e-18 67.9 0.0 1.6e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ90615.1 - 1.8e-13 50.1 0.0 2.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAQ90615.1 - 2.3e-07 30.7 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EAQ90615.1 - 8.5e-07 28.3 0.0 1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAQ90615.1 - 2.1e-06 27.3 0.0 4.1e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EAQ90615.1 - 0.00092 18.4 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAQ90615.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EAQ90615.1 - 0.0015 18.2 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 NTPase SRPRB PF09439.5 EAQ90615.1 - 0.0027 16.9 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EAQ90615.1 - 0.003 17.2 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EAQ90615.1 - 0.0047 16.5 0.2 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAQ90615.1 - 0.0055 16.4 0.2 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EAQ90615.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EAQ90615.1 - 0.0061 16.0 0.1 0.095 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EAQ90615.1 - 0.0074 15.7 0.2 0.011 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 EAQ90615.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EAQ90615.1 - 0.0092 15.5 0.2 0.38 10.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 EAQ90615.1 - 0.012 14.6 0.0 0.029 13.3 0.0 1.7 2 0 0 2 2 2 0 Septin MobB PF03205.9 EAQ90615.1 - 0.017 14.7 0.1 0.056 13.1 0.0 1.8 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EAQ90615.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EAQ90615.1 - 0.09 12.0 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 EAQ90615.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EAQ90615.1 - 0.13 11.1 0.2 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF914 PF06027.7 EAQ90616.1 - 2.8e-06 26.4 7.1 2.8e-06 26.4 4.9 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EAQ90616.1 - 1.4e-05 24.1 10.1 2.4e-05 23.3 7.0 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EAQ90616.1 - 5.1e-05 23.4 4.6 5.1e-05 23.4 3.2 3.7 3 2 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EAQ90616.1 - 0.00047 20.1 6.5 0.00047 20.1 4.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.1 EAQ90616.1 - 0.005 16.3 0.7 0.005 16.3 0.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) TPT PF03151.11 EAQ90616.1 - 2.7 7.6 28.2 0.14 11.8 4.0 2.6 3 0 0 3 3 3 0 Triose-phosphate Transporter family WD40 PF00400.27 EAQ90617.1 - 1.4e-20 72.3 1.5 6.6e-07 28.9 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat VID27 PF08553.5 EAQ90617.1 - 0.042 12.0 0.0 0.063 11.5 0.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Spb1_C PF07780.7 EAQ90618.1 - 1.1e-83 279.9 21.1 1.1e-83 279.9 14.6 2.8 2 1 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EAQ90618.1 - 1.4e-55 187.1 12.9 1.4e-55 187.1 9.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EAQ90618.1 - 2.2e-55 187.4 0.1 6e-55 186.0 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Sterol-sensing PF12349.3 EAQ90619.1 - 3.2e-40 137.1 10.4 5.8e-40 136.2 7.2 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EAQ90619.1 - 4.2e-12 44.8 2.3 5.5e-12 44.4 1.6 1.2 1 0 0 1 1 1 1 Patched family Dimer_Tnp_hAT PF05699.9 EAQ90620.1 - 7.5e-13 47.9 0.1 1.8e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region 14-3-3 PF00244.15 EAQ90623.1 - 7.9e-09 34.9 0.2 3.5e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein Collagen PF01391.13 EAQ90623.1 - 0.0081 15.6 6.6 0.0081 15.6 4.6 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) zf-C3HC4_4 PF15227.1 EAQ90624.1 - 0.52 10.2 0.1 0.52 10.2 0.1 3.4 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING DUF4202 PF13875.1 EAQ90625.1 - 1.3e-68 230.2 0.0 1.5e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Med5 PF08689.5 EAQ90626.1 - 8.2e-237 788.4 0.0 4.6e-197 656.9 0.0 2.1 1 1 1 2 2 2 2 Mediator complex subunit Med5 Syndecan PF01034.15 EAQ90626.1 - 0.076 12.6 0.4 0.76 9.4 0.1 2.3 2 0 0 2 2 2 0 Syndecan domain zf-C4H2 PF10146.4 EAQ90626.1 - 3.9 7.4 7.4 2 8.3 0.5 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein Dynamin_N PF00350.18 EAQ90630.1 - 1.5e-41 142.0 0.0 3.4e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAQ90630.1 - 9.9e-08 31.1 0.1 5.4e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EAQ90630.1 - 0.0013 18.6 0.1 0.0064 16.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ90630.1 - 0.0015 19.0 0.1 0.0091 16.4 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 EAQ90630.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 EAQ90631.1 - 1.2e-15 56.9 0.0 2.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EAQ90631.1 - 9.2e-09 35.3 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EAQ90631.1 - 4.9e-06 25.4 0.0 6.1e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Cation_efflux PF01545.16 EAQ90632.1 - 2.9e-20 72.5 11.2 1.7e-18 66.6 6.1 2.2 2 0 0 2 2 2 2 Cation efflux family Pkinase PF00069.20 EAQ90634.1 - 3.9e-20 72.0 0.0 1.2e-17 63.9 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ90634.1 - 6.7e-16 58.1 0.1 6.6e-12 45.0 0.0 3.9 1 1 1 2 2 2 2 Protein tyrosine kinase zf-MYND PF01753.13 EAQ90635.1 - 7.3e-08 32.1 19.6 1.9e-07 30.8 13.6 1.8 1 0 0 1 1 1 1 MYND finger Ebp2 PF05890.7 EAQ90636.1 - 2.8e-95 318.7 13.2 2.8e-95 318.7 9.1 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF1768 PF08719.6 EAQ90636.1 - 0.013 15.1 1.3 0.013 15.1 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) H_kinase_N PF12282.3 EAQ90636.1 - 0.049 13.2 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Signal transduction histidine kinase HHA PF05321.6 EAQ90636.1 - 0.52 10.4 4.7 0.87 9.7 0.2 2.8 3 0 0 3 3 3 0 Haemolysin expression modulating protein HTH_31 PF13560.1 EAQ90637.1 - 7.4e-05 22.8 0.2 9.3e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EAQ90637.1 - 0.0043 16.8 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_AsnC-type PF13404.1 EAQ90637.1 - 0.065 12.7 0.5 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 EAQ90637.1 - 0.12 11.7 0.1 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 MMR_HSR1 PF01926.18 EAQ90639.1 - 1.1e-09 38.2 0.0 2.7e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAQ90639.1 - 4.6e-06 25.8 0.0 1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_17 PF13207.1 EAQ90639.1 - 0.00023 21.9 1.7 0.00058 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ90639.1 - 0.00047 19.3 0.1 0.0015 17.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAQ90639.1 - 0.0012 18.1 0.1 0.0049 16.1 0.0 2.1 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ90639.1 - 0.0018 18.0 10.0 0.17 11.6 0.1 3.6 2 2 1 3 3 3 2 Dynamin family AAA_18 PF13238.1 EAQ90639.1 - 0.0032 17.7 0.5 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain GBP PF02263.14 EAQ90639.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_22 PF13401.1 EAQ90639.1 - 0.0039 17.3 0.2 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EAQ90639.1 - 0.0098 16.1 4.1 0.012 15.9 0.0 2.7 2 1 0 2 2 2 1 ABC transporter DUF87 PF01935.12 EAQ90639.1 - 0.026 14.3 0.3 0.026 14.3 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_29 PF13555.1 EAQ90639.1 - 0.033 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EAQ90639.1 - 0.037 13.7 0.3 0.28 10.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAQ90639.1 - 0.037 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein IIGP PF05049.8 EAQ90639.1 - 0.064 12.0 2.2 0.31 9.7 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 EAQ90639.1 - 0.078 12.1 1.7 0.16 11.1 0.0 2.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 EAQ90639.1 - 0.079 12.3 0.1 0.079 12.3 0.0 2.3 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EAQ90639.1 - 0.081 12.7 0.0 0.081 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EAQ90639.1 - 0.089 12.2 0.5 1.5 8.2 0.3 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EAQ90639.1 - 0.28 9.8 0.0 0.28 9.8 0.0 2.4 2 1 1 3 3 2 0 G-protein alpha subunit ATP_bind_1 PF03029.12 EAQ90639.1 - 0.97 8.9 4.8 0.29 10.6 0.1 2.4 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EAQ90640.1 - 4.6e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAQ90640.1 - 0.00086 18.5 0.3 0.0027 16.9 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EAQ90640.1 - 0.0074 15.4 0.0 0.0074 15.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family MobB PF03205.9 EAQ90640.1 - 0.018 14.7 0.2 0.049 13.3 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EAQ90640.1 - 0.032 14.5 4.6 0.043 14.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EAQ90640.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EAQ90640.1 - 0.036 14.5 0.5 0.099 13.1 0.0 2.1 2 1 0 2 2 2 0 Miro-like protein SRP54 PF00448.17 EAQ90640.1 - 0.042 13.2 0.4 0.19 11.1 0.2 2.1 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.18 EAQ90640.1 - 0.065 13.0 0.1 0.065 13.0 0.1 3.9 2 2 1 3 3 2 0 Dynamin family UPF0079 PF02367.12 EAQ90640.1 - 0.081 12.5 1.5 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EAQ90640.1 - 0.083 12.5 0.9 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EAQ90640.1 - 0.09 12.6 0.0 0.09 12.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EAQ90640.1 - 0.1 11.6 0.1 0.1 11.6 0.0 2.5 2 1 1 3 3 3 0 KaiC AAA_22 PF13401.1 EAQ90640.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EAQ90640.1 - 0.16 12.8 0.0 0.16 12.8 0.0 2.6 2 1 0 2 2 1 0 AAA domain cobW PF02492.14 EAQ90640.1 - 0.21 10.9 0.2 0.21 10.9 0.1 2.4 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF1154 PF06631.6 EAQ90640.1 - 7.8 6.2 7.9 6.7 6.4 0.3 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1154) ABC_tran PF00005.22 EAQ90640.1 - 8.4 6.6 11.0 0.74 10.1 0.1 2.8 2 2 0 2 2 2 0 ABC transporter Menin PF05053.8 EAQ90641.1 - 2.3 6.2 7.0 2.7 6.0 4.9 1.1 1 0 0 1 1 1 0 Menin B-block_TFIIIC PF04182.7 EAQ90642.1 - 8.2e-17 60.8 0.0 6.8e-16 57.8 0.0 2.6 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC UQ_con PF00179.21 EAQ90643.1 - 1.1e-21 76.6 0.0 1.5e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAQ90643.1 - 0.059 13.2 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain zf-C2H2_4 PF13894.1 EAQ90644.1 - 4.1e-08 33.0 11.4 0.026 14.8 0.3 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EAQ90644.1 - 0.00021 21.0 12.9 0.34 10.8 0.1 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ90644.1 - 0.00093 19.4 16.9 0.052 13.9 0.5 4.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EAQ90644.1 - 0.013 15.5 9.6 0.65 10.1 0.0 3.8 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EAQ90644.1 - 0.03 14.6 0.2 0.03 14.6 0.1 4.4 4 1 0 4 4 4 0 Zinc-finger double domain Yippee-Mis18 PF03226.9 EAQ90644.1 - 1.2 9.2 4.1 1.2 9.1 0.9 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 EAQ90644.1 - 5.2 6.8 12.8 2.9 7.6 0.4 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zf-DHHC PF01529.15 EAQ90645.1 - 1e-43 148.7 7.7 1e-43 148.7 5.3 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase DZR PF12773.2 EAQ90645.1 - 0.041 13.7 6.7 0.12 12.1 4.6 1.8 1 0 0 1 1 1 0 Double zinc ribbon YL1 PF05764.8 EAQ90645.1 - 0.056 13.0 2.6 0.095 12.2 1.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pex14_N PF04695.8 EAQ90645.1 - 0.083 12.9 2.3 0.18 11.8 0.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 EAQ90645.1 - 2.9 6.0 10.2 4.8 5.2 7.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PI-PLC-X PF00388.14 EAQ90646.1 - 1.1e-57 193.5 0.0 2.2e-57 192.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAQ90646.1 - 3.5e-39 133.4 0.0 7.9e-39 132.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EAQ90646.1 - 9.9e-09 34.9 0.0 2.7e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 EAQ90646.1 - 0.0011 18.9 0.1 0.004 17.1 0.0 2.0 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like SinI PF08671.5 EAQ90646.1 - 0.26 10.7 0.9 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Anti-repressor SinI Zw10 PF06248.8 EAQ90650.1 - 5.6e-11 41.3 2.1 1.1e-06 27.1 1.7 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EAQ90650.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal TPR_MLP1_2 PF07926.7 EAQ90650.1 - 0.13 11.9 4.7 0.36 10.5 3.3 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ribosomal_L36e PF01158.13 EAQ90651.1 - 3.2e-40 136.0 5.7 3.6e-40 135.8 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EAQ90651.1 - 0.015 14.3 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.4 EAQ90651.1 - 0.056 13.2 1.1 0.065 13.0 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Mei5 PF10376.4 EAQ90651.1 - 0.12 11.8 2.8 0.13 11.7 0.2 1.9 1 1 1 2 2 2 0 Double-strand recombination repair protein Peptidase_M16_C PF05193.16 EAQ90652.1 - 6.2e-20 71.6 0.0 5.3e-14 52.3 0.0 2.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAQ90652.1 - 0.00012 21.8 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 EAQ90652.1 - 0.096 11.5 3.0 7.2 5.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Sporozoite_P67 PF05642.6 EAQ90652.1 - 0.096 10.5 2.4 0.14 10.0 1.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RQC PF09382.5 EAQ90652.1 - 0.14 11.8 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 RQC domain Acetyltransf_1 PF00583.19 EAQ90654.1 - 3.9e-16 58.8 0.0 7.2e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ90654.1 - 4.4e-07 29.9 0.1 1e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ90654.1 - 4.3e-06 26.3 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EAQ90654.1 - 2.4e-05 24.2 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAQ90654.1 - 4e-05 23.7 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAQ90654.1 - 0.0002 21.3 0.1 0.0004 20.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAQ90654.1 - 0.00045 20.0 0.0 0.00058 19.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NMO PF03060.10 EAQ90655.1 - 7.5e-51 173.2 8.6 1.3e-50 172.4 5.9 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAQ90655.1 - 6e-06 25.3 0.0 0.063 12.1 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAQ90655.1 - 0.13 11.0 8.3 0.22 10.2 5.7 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Pneumo_att_G PF05539.6 EAQ90656.1 - 3.5 6.9 6.1 5.2 6.3 4.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Taxilin PF09728.4 EAQ90657.1 - 3.4e-82 276.0 61.0 3.6e-53 180.6 27.8 2.7 2 1 0 2 2 2 2 Myosin-like coiled-coil protein AAA_13 PF13166.1 EAQ90657.1 - 0.0021 16.6 37.2 0.0025 16.3 8.9 2.1 2 0 0 2 2 2 2 AAA domain bZIP_2 PF07716.10 EAQ90657.1 - 0.026 14.3 2.4 0.026 14.3 1.6 5.3 5 0 0 5 5 5 0 Basic region leucine zipper TMF_TATA_bd PF12325.3 EAQ90657.1 - 0.057 13.1 52.8 1.5 8.5 5.3 5.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 EAQ90657.1 - 8.4 6.7 20.3 4.1 7.7 2.0 4.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein M16C_assoc PF08367.6 EAQ90658.1 - 6.9e-57 192.1 0.0 1e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EAQ90658.1 - 2.3e-37 128.4 0.0 2.2e-22 79.6 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAQ90658.1 - 0.0048 16.6 0.1 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) HHH_8 PF14716.1 EAQ90658.1 - 0.055 13.6 0.0 0.35 11.0 0.0 2.4 3 0 0 3 3 3 0 Helix-hairpin-helix domain Orn_Arg_deC_N PF02784.11 EAQ90659.1 - 4.5e-79 265.1 0.0 6.4e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EAQ90659.1 - 4.2e-32 110.3 0.1 9.5e-32 109.1 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Nif11 PF07862.6 EAQ90659.1 - 0.032 14.1 0.1 0.51 10.3 0.1 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Pribosyl_synth PF14572.1 EAQ90660.1 - 1.4e-40 138.9 1.7 3e-34 118.3 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EAQ90660.1 - 6.2e-28 96.8 0.0 6.4e-27 93.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EAQ90660.1 - 3.3e-11 42.9 0.8 9e-11 41.5 0.6 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Sugar_tr PF00083.19 EAQ90661.1 - 1.3e-64 218.4 14.6 2.2e-59 201.2 4.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ90661.1 - 1.1e-13 50.6 24.4 1.7e-11 43.4 8.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PTPS_related PF10131.4 EAQ90661.1 - 0.0083 14.3 1.2 0.013 13.6 0.3 1.6 2 0 0 2 2 2 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein WD40 PF00400.27 EAQ90662.1 - 5.1e-36 121.2 3.9 1.3e-07 31.2 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EAQ90662.1 - 1.8e-06 27.8 0.1 0.044 13.4 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DCX PF03607.12 EAQ90662.1 - 0.17 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Doublecortin DUF2838 PF10998.3 EAQ90663.1 - 1.4e-47 160.2 11.1 1.4e-47 160.2 7.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Tropomyosin_1 PF12718.2 EAQ90663.1 - 0.033 14.0 0.3 0.059 13.2 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.15 EAQ90663.1 - 0.062 12.3 1.2 0.094 11.7 0.8 1.2 1 0 0 1 1 1 0 Tropomyosin Atg14 PF10186.4 EAQ90663.1 - 0.15 10.9 1.2 0.23 10.3 0.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EAQ90663.1 - 0.19 11.2 1.7 0.31 10.5 1.2 1.2 1 0 0 1 1 1 0 IncA protein Val_tRNA-synt_C PF10458.4 EAQ90663.1 - 0.52 10.4 2.6 14 5.8 0.6 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SMC_N PF02463.14 EAQ90664.1 - 9.4e-43 145.9 0.0 3.2e-42 144.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAQ90664.1 - 5.1e-26 90.9 0.0 2.4e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 EAQ90664.1 - 3.1e-08 33.1 23.4 0.0051 16.0 1.5 5.2 4 1 0 5 5 5 3 Reovirus sigma C capsid protein AAA_21 PF13304.1 EAQ90664.1 - 1.7e-05 24.9 0.2 1.7e-05 24.9 0.1 3.0 2 1 1 3 3 3 1 AAA domain IncA PF04156.9 EAQ90664.1 - 0.00047 19.8 111.9 0.0084 15.7 16.6 6.8 3 2 3 6 6 5 4 IncA protein SbcCD_C PF13558.1 EAQ90664.1 - 0.0039 17.0 0.0 0.022 14.6 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF948 PF06103.6 EAQ90664.1 - 0.0084 15.9 1.4 0.0084 15.9 1.0 6.1 6 1 1 7 7 7 1 Bacterial protein of unknown function (DUF948) ADIP PF11559.3 EAQ90664.1 - 0.01 15.7 1.7 0.01 15.7 1.2 9.1 4 2 4 9 9 8 0 Afadin- and alpha -actinin-Binding Glutaredoxin2_C PF04399.8 EAQ90664.1 - 0.082 12.4 0.1 0.082 12.4 0.1 4.9 4 2 1 5 5 5 0 Glutaredoxin 2, C terminal domain ATG16 PF08614.6 EAQ90664.1 - 0.098 12.4 104.4 1.4 8.7 2.7 7.4 3 2 4 7 7 7 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EAQ90664.1 - 0.56 8.8 102.8 0.032 12.9 0.9 6.9 3 2 4 7 7 7 0 Spc7 kinetochore protein AAA_13 PF13166.1 EAQ90664.1 - 0.96 7.8 100.0 0.37 9.2 18.8 5.8 3 3 2 5 5 5 0 AAA domain Laminin_II PF06009.7 EAQ90664.1 - 1.7 8.3 65.9 0.074 12.8 2.8 8.0 4 2 3 8 8 8 0 Laminin Domain II TFIIE_alpha PF02002.12 EAQ90665.1 - 1.3e-14 53.5 0.1 2.2e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EAQ90665.1 - 0.0093 15.2 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 EAQ90665.1 - 0.012 15.0 5.8 0.11 12.0 4.0 2.2 1 1 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HIT PF04438.11 EAQ90665.1 - 0.025 14.1 1.3 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger Zn-ribbon_8 PF09723.5 EAQ90665.1 - 0.032 14.1 0.9 0.11 12.4 0.5 2.0 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EAQ90665.1 - 0.088 12.6 0.8 0.2 11.5 0.6 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.8 EAQ90665.1 - 0.092 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DNA_pol_lambd_f PF10391.4 EAQ90666.1 - 2.8e-22 78.0 2.0 4.6e-22 77.3 0.5 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EAQ90666.1 - 2.4e-19 69.4 0.0 5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EAQ90666.1 - 4.1e-18 64.8 0.0 1e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.1 EAQ90666.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EAQ90666.1 - 0.029 14.6 0.1 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase domain HHH_8 PF14716.1 EAQ90666.1 - 0.046 13.9 0.0 0.48 10.6 0.0 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix domain MAPEG PF01124.13 EAQ90667.1 - 9.8e-27 93.1 1.5 1.2e-26 92.8 1.1 1.1 1 0 0 1 1 1 1 MAPEG family WIF PF02019.13 EAQ90668.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 WIF domain Sec23_trunk PF04811.10 EAQ90669.1 - 4.2e-80 268.6 0.0 5.8e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EAQ90669.1 - 4.5e-34 115.9 0.9 1.5e-33 114.2 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EAQ90669.1 - 3e-31 107.7 0.2 6.8e-31 106.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAQ90669.1 - 3.1e-16 58.6 6.5 6.4e-16 57.6 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EAQ90669.1 - 6.5e-13 48.1 0.0 1.5e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EAQ90670.1 - 4.6e-18 64.4 0.1 7.3e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EAQ90670.1 - 3.6e-11 43.0 0.1 6e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ACC_epsilon PF13822.1 EAQ90671.1 - 6.5 7.1 8.6 2 8.7 2.7 2.2 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Glyco_transf_41 PF13844.1 EAQ90672.1 - 1.7e-78 263.7 0.1 6.1e-48 162.9 0.0 4.1 1 1 2 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.23 EAQ90672.1 - 4.6e-23 79.8 5.6 9.1e-05 21.9 0.0 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ90672.1 - 7e-20 70.4 4.8 5.9e-05 22.6 0.0 6.1 4 2 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 EAQ90672.1 - 7e-18 63.0 8.7 0.00038 20.1 0.0 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ90672.1 - 1.9e-14 52.2 0.3 0.015 15.0 0.0 6.1 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ90672.1 - 6.6e-14 51.6 0.8 2.3e-07 30.6 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ90672.1 - 2.8e-10 39.5 0.4 0.0056 16.7 0.0 4.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ90672.1 - 1.1e-08 35.4 9.4 0.0079 16.8 0.2 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ90672.1 - 2.4e-08 33.8 11.1 0.00067 20.0 0.1 6.8 7 2 2 9 9 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ90672.1 - 4.2e-08 32.4 6.0 0.23 11.3 0.0 6.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ90672.1 - 9.5e-07 28.5 12.2 0.074 13.0 0.6 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90672.1 - 2.2e-05 24.6 0.5 4.7 7.8 0.0 4.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ90672.1 - 5.7e-05 23.3 0.9 9.5 6.6 0.0 4.2 3 1 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ90672.1 - 0.00049 19.8 0.2 2.6 7.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.2 EAQ90672.1 - 0.0053 16.7 0.1 0.18 11.8 0.0 3.0 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_15 PF13429.1 EAQ90672.1 - 0.011 14.7 0.0 0.1 11.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 EAQ90672.1 - 0.025 14.8 1.2 12 6.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Myb_DNA-binding PF00249.26 EAQ90673.1 - 1.4e-18 66.6 0.7 7.8e-09 35.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ90673.1 - 1.2e-16 60.5 0.5 1.2e-10 41.2 0.0 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_Tnp_1 PF01527.15 EAQ90673.1 - 0.0085 16.0 0.1 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Transposase Myb_DNA-bind_4 PF13837.1 EAQ90673.1 - 0.25 11.4 3.1 2.5 8.3 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EAQ90673.1 - 0.42 10.8 4.7 0.64 10.2 1.5 2.2 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Orthopox_F8 PF05886.6 EAQ90673.1 - 1.1 9.1 5.2 0.51 10.2 1.4 2.1 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Lambda_CIII PF02061.11 EAQ90676.1 - 0.065 13.2 0.1 8.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Lambda Phage CIII DUF2414 PF10309.4 EAQ90677.1 - 2.7e-22 78.2 0.0 5.9e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF3015 PF11220.3 EAQ90678.1 - 0.0013 18.3 0.1 0.018 14.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3015) DUF3584 PF12128.3 EAQ90678.1 - 0.017 12.4 11.9 0.022 12.1 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KcnmB2_inactiv PF09303.5 EAQ90678.1 - 0.021 14.5 1.4 0.052 13.3 1.0 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain DUF3227 PF11537.3 EAQ90678.1 - 0.051 13.6 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) Tropomyosin PF00261.15 EAQ90678.1 - 0.058 12.4 22.8 0.31 10.0 4.2 2.1 1 1 1 2 2 2 0 Tropomyosin AAA_10 PF12846.2 EAQ90678.1 - 0.061 12.7 0.2 0.095 12.1 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain EMP24_GP25L PF01105.19 EAQ90678.1 - 0.13 11.9 9.6 1.4 8.5 0.7 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Exonuc_VII_L PF02601.10 EAQ90678.1 - 0.17 11.0 7.0 0.24 10.5 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 EAQ90678.1 - 0.17 11.4 18.0 0.29 10.7 12.5 1.3 1 0 0 1 1 1 0 IncA protein DUF3373 PF11853.3 EAQ90678.1 - 0.37 9.2 1.9 0.57 8.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) zf-C4H2 PF10146.4 EAQ90678.1 - 0.53 10.2 7.0 0.99 9.3 4.8 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Tropomyosin_1 PF12718.2 EAQ90678.1 - 0.78 9.5 24.6 4.2 7.2 5.7 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF3774 PF12609.3 EAQ90678.1 - 1.1 10.1 4.5 7.9 7.4 0.4 2.7 2 0 0 2 2 2 0 Wound-induced protein OEP PF02321.13 EAQ90678.1 - 1.6 8.3 13.6 1.3 8.5 3.7 2.4 1 1 1 2 2 2 0 Outer membrane efflux protein DUF4279 PF14106.1 EAQ90678.1 - 1.9 8.4 8.9 0.45 10.4 0.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) DUF4140 PF13600.1 EAQ90678.1 - 2.9 8.4 12.1 0.49 10.8 0.7 3.0 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.4 EAQ90678.1 - 3.2 7.9 7.3 1.2 9.2 1.1 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 EAQ90678.1 - 5.3 6.8 8.6 20 4.9 1.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.4 EAQ90678.1 - 6.4 5.0 10.7 3.9 5.7 6.2 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Laminin_II PF06009.7 EAQ90678.1 - 8.1 6.2 9.0 3.9 7.2 1.2 2.4 1 1 2 3 3 3 0 Laminin Domain II YlqD PF11068.3 EAQ90678.1 - 9.3 6.2 18.4 2.2 8.3 2.7 2.2 1 1 1 2 2 2 0 YlqD protein Pet127 PF08634.5 EAQ90681.1 - 1.5e-121 404.8 0.4 2.2e-121 404.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Rhomboid PF01694.17 EAQ90682.1 - 2.2e-32 112.1 11.0 2.2e-32 112.1 7.6 1.9 3 0 0 3 3 3 1 Rhomboid family DUF1426 PF07234.6 EAQ90682.1 - 0.42 10.3 2.3 5.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) TPPK_C PF12555.3 EAQ90682.1 - 4.1 7.2 8.8 9.6 6.0 0.2 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MRF_C2 PF13888.1 EAQ90684.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Cohesin_load PF10345.4 EAQ90686.1 - 1.6e-164 548.5 4.1 8.5e-107 357.8 2.3 2.3 1 1 1 2 2 2 2 Cohesin loading factor Abhydrolase_1 PF00561.15 EAQ90687.1 - 1.8e-10 40.7 0.0 2.2e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAQ90687.1 - 3.7e-09 36.7 0.1 8e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ90687.1 - 0.0005 19.8 0.1 0.0034 17.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 EAQ90687.1 - 0.04 13.6 0.0 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Cutinase SAM_PNT PF02198.11 EAQ90687.1 - 0.069 12.9 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain IGPD PF00475.13 EAQ90689.1 - 2.6e-60 202.4 0.2 4.1e-60 201.8 0.1 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.6 EAQ90691.1 - 2.8e-20 72.1 0.0 5.5e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EAQ90691.1 - 2.3e-11 44.0 0.0 4.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAQ90691.1 - 3.2e-11 43.1 0.0 1.9e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EAQ90691.1 - 5e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ90691.1 - 5.6e-06 26.4 0.1 0.00021 21.3 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 EAQ90691.1 - 1.6e-05 23.8 0.0 0.014 14.1 0.0 2.7 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EAQ90691.1 - 4.8e-05 23.4 0.2 0.011 15.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAQ90691.1 - 5.4e-05 22.3 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EAQ90691.1 - 0.00027 20.5 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EAQ90691.1 - 0.00035 20.1 0.0 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EAQ90691.1 - 0.00069 19.1 0.1 0.14 11.5 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 EAQ90691.1 - 0.0018 17.4 0.0 0.024 13.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 EAQ90691.1 - 0.0019 17.7 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EAQ90691.1 - 0.0047 16.3 0.0 0.51 9.6 0.0 2.6 1 1 1 2 2 2 1 AAA domain DNA_pol3_gamma3 PF12169.3 EAQ90691.1 - 0.0071 16.0 0.1 0.31 10.8 0.0 2.6 2 0 0 2 2 2 1 DNA polymerase III subunits gamma and tau domain III NTPase_1 PF03266.10 EAQ90691.1 - 0.0088 15.7 0.6 0.057 13.1 0.1 2.3 2 1 1 3 3 2 1 NTPase AAA_19 PF13245.1 EAQ90691.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 EAQ90691.1 - 0.019 14.4 0.1 0.19 11.2 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_31 PF13614.1 EAQ90691.1 - 0.02 14.8 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EAQ90691.1 - 0.023 13.4 0.0 0.047 12.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein KTI12 PF08433.5 EAQ90691.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EAQ90691.1 - 0.029 14.1 0.4 0.15 11.7 0.1 2.3 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EAQ90691.1 - 0.048 13.2 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ90691.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAQ90691.1 - 0.091 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgJ PF01960.13 EAQ90692.1 - 8.8e-150 498.4 0.3 1e-149 498.2 0.2 1.0 1 0 0 1 1 1 1 ArgJ family DER1 PF04511.10 EAQ90693.1 - 5e-25 88.1 1.6 5.9e-25 87.9 1.1 1.0 1 0 0 1 1 1 1 Der1-like family DUF2269 PF10027.4 EAQ90693.1 - 0.051 13.3 0.4 0.051 13.3 0.3 1.8 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) CD99L2 PF12301.3 EAQ90694.1 - 0.08 12.6 0.0 0.08 12.6 0.0 4.2 3 1 0 3 3 3 0 CD99 antigen like protein 2 Methyltransf_23 PF13489.1 EAQ90696.1 - 4.9e-24 84.8 0.0 7.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ90696.1 - 0.00092 18.8 0.0 0.61 9.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ90696.1 - 0.00094 19.7 0.0 0.71 10.4 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ90696.1 - 0.0084 16.5 0.0 0.25 11.8 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ90696.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DUF1421 PF07223.6 EAQ90697.1 - 0.081 12.6 11.0 0.11 12.2 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Tuberculin PF12198.3 EAQ90699.1 - 0.016 15.0 0.4 0.044 13.6 0.3 1.8 1 0 0 1 1 1 0 Theoretical tuberculin protein CN_hydrolase PF00795.17 EAQ90700.1 - 1.4e-11 44.1 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DKCLD PF08068.7 EAQ90702.1 - 6e-30 102.9 0.3 3.4e-29 100.5 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EAQ90702.1 - 2.2e-22 79.8 5.6 5.4e-21 75.3 0.2 3.4 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EAQ90702.1 - 2.2e-21 75.3 0.9 5e-21 74.1 0.6 1.6 1 0 0 1 1 1 1 PUA domain Chorion_2 PF03964.10 EAQ90702.1 - 0.044 14.3 2.4 0.081 13.4 1.6 1.4 1 0 0 1 1 1 0 Chorion family 2 RNA_polI_A34 PF08208.6 EAQ90702.1 - 1.9 8.1 21.8 3.2 7.3 15.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.7 EAQ90702.1 - 8.1 6.2 14.6 11 5.8 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 EAQ90702.1 - 9.7 5.0 9.3 15 4.3 6.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SAC3_GANP PF03399.11 EAQ90704.1 - 8e-43 146.3 0.1 1.2e-42 145.7 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EAQ90704.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Methyltransf_11 PF08241.7 EAQ90705.1 - 2.9e-06 27.6 0.0 6.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ90705.1 - 7.6e-06 26.3 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ90705.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ90705.1 - 0.0016 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EAQ90705.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EAQ90705.1 - 0.011 14.8 0.0 0.054 12.5 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3419 PF11899.3 EAQ90705.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) CN_hydrolase PF00795.17 EAQ90706.1 - 1.5e-26 92.8 0.0 2.9e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EAQ90706.1 - 1.7e-14 53.3 0.0 3.1e-11 42.6 0.0 2.8 1 1 0 1 1 1 1 NAD synthase Polyketide_cyc PF03364.15 EAQ90707.1 - 8.1e-19 67.8 0.8 1.1e-14 54.4 0.1 2.3 1 1 1 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport TPR_11 PF13414.1 EAQ90710.1 - 1.3e-09 37.5 3.3 6.2e-05 22.5 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAQ90710.1 - 3.2e-09 35.9 2.1 0.00012 21.7 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ90710.1 - 3.6e-09 36.8 0.4 0.00039 20.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ90710.1 - 1.8e-06 28.0 9.4 0.017 15.7 0.1 5.6 4 4 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ90710.1 - 1.6e-05 25.4 0.3 1.6e-05 25.4 0.2 3.8 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ90710.1 - 0.00022 21.1 1.3 0.17 11.8 0.0 3.4 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ90710.1 - 0.00065 19.3 0.0 0.01 15.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ90710.1 - 0.0055 16.8 0.2 0.032 14.4 0.0 2.5 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90710.1 - 0.013 15.9 2.0 19 6.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ90710.1 - 0.026 14.3 3.0 0.61 9.9 0.2 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ90710.1 - 0.027 14.0 0.1 0.45 10.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ90710.1 - 0.041 13.6 0.3 4.9 7.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EAQ90710.1 - 0.097 12.7 3.3 2.7 8.1 0.0 3.5 2 1 1 4 4 4 0 Tetratricopeptide repeat Adaptin_N PF01602.15 EAQ90711.1 - 8.7e-76 255.3 0.0 1.4e-75 254.5 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region GKAP PF03359.8 EAQ90711.1 - 0.039 13.5 0.6 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein TGT PF01702.13 EAQ90712.1 - 4.1e-35 121.1 0.0 5.3e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.14 EAQ90713.1 - 4.2e-11 42.6 0.3 6.7e-11 42.0 0.2 1.3 1 0 0 1 1 1 1 LCCL domain RRN3 PF05327.6 EAQ90714.1 - 0.16 10.0 2.0 0.21 9.6 1.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Filament PF00038.16 EAQ90715.1 - 0.0025 17.3 15.2 0.0025 17.3 10.5 4.4 2 1 2 4 4 4 2 Intermediate filament protein HALZ PF02183.13 EAQ90715.1 - 0.15 11.7 0.1 0.15 11.7 0.1 5.5 6 0 0 6 6 6 0 Homeobox associated leucine zipper COG5 PF10392.4 EAQ90715.1 - 0.27 11.2 10.9 0.024 14.5 2.7 2.8 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 EAQ90715.1 - 0.6 9.2 9.6 1.3 8.1 5.7 2.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EAQ90715.1 - 0.64 7.8 14.3 1.1 7.0 9.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3658 PF12395.3 EAQ90715.1 - 1.2 8.7 6.7 1.6 8.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function Peptidase_S46 PF10459.4 EAQ90715.1 - 1.5 7.1 22.1 2.6 6.3 15.3 1.3 1 0 0 1 1 1 0 Peptidase S46 NYD-SP28_assoc PF14775.1 EAQ90715.1 - 1.7 8.4 10.4 6.5 6.5 0.2 3.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain FlaC_arch PF05377.6 EAQ90715.1 - 4.9 7.1 28.9 0.07 13.0 0.6 6.9 7 1 0 7 7 7 0 Flagella accessory protein C (FlaC) Transketolase_N PF00456.16 EAQ90716.1 - 2.6e-148 493.2 0.0 3.5e-148 492.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EAQ90716.1 - 6.4e-44 149.5 0.0 1.1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EAQ90716.1 - 1.9e-14 53.6 0.0 4.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EAQ90716.1 - 5.2e-05 22.3 0.0 0.00013 21.0 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF3115 PF11312.3 EAQ90717.1 - 8.1e-102 340.3 0.0 1.2e-101 339.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Syja_N PF02383.13 EAQ90718.1 - 4.4e-98 327.9 0.0 6e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EAQ90718.1 - 1.8e-35 120.7 0.0 3.1e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase PG_binding_3 PF09374.5 EAQ90718.1 - 0.0088 16.0 0.1 0.059 13.3 0.1 2.3 2 0 0 2 2 2 1 Predicted Peptidoglycan domain ATP-synt_C PF00137.16 EAQ90719.1 - 1.8e-30 104.6 30.5 1.3e-18 66.6 9.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ycf1 PF05758.7 EAQ90720.1 - 0.015 13.0 8.6 0.017 12.8 5.9 1.1 1 0 0 1 1 1 0 Ycf1 PAT1 PF09770.4 EAQ90720.1 - 0.24 9.5 53.7 0.27 9.4 37.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF966 PF06136.8 EAQ90720.1 - 0.33 10.3 15.6 0.4 10.0 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Fibrinogen_BP PF08017.6 EAQ90720.1 - 0.42 8.7 20.0 0.53 8.4 13.9 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein DUF4045 PF13254.1 EAQ90720.1 - 2.2 7.4 20.2 2.6 7.2 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 EAQ90720.1 - 2.6 7.0 17.3 3.1 6.8 12.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAPS PF04499.10 EAQ90720.1 - 3.7 6.0 14.2 4.1 5.9 9.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Parvo_coat PF00740.13 EAQ90720.1 - 5.4 5.8 23.9 6.4 5.6 16.6 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 ERG4_ERG24 PF01222.12 EAQ90721.1 - 4.8e-102 341.6 18.5 6.6e-55 186.3 5.5 2.9 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family Ank_2 PF12796.2 EAQ90721.1 - 1.8e-33 114.7 3.3 9.6e-14 51.4 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ90721.1 - 3.6e-21 73.8 10.7 1.3e-05 24.7 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EAQ90721.1 - 7.5e-20 70.9 7.2 6.3e-09 36.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ90721.1 - 1.9e-19 67.7 6.8 0.0064 16.6 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EAQ90721.1 - 7.9e-15 54.5 16.2 9.2e-07 28.9 0.6 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) L_HGMIC_fpl PF10242.4 EAQ90722.1 - 0.0002 21.4 0.1 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.1 EAQ90722.1 - 0.0011 18.6 0.8 0.0073 16.0 0.6 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.20 EAQ90723.1 - 5.1e-47 160.2 0.0 1.3e-39 135.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ90723.1 - 1.2e-30 106.4 0.0 1.2e-27 96.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ90723.1 - 0.00058 18.9 0.0 0.0014 17.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like DUF2321 PF10083.4 EAQ90723.1 - 0.35 10.3 0.1 0.68 9.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Mur_ligase_M PF08245.7 EAQ90725.1 - 9.1e-07 29.1 0.2 2.5e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EAQ90725.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain 7tm_4 PF13853.1 EAQ90726.1 - 0.0022 17.8 6.2 0.0031 17.3 4.3 1.1 1 0 0 1 1 1 1 Olfactory receptor PRA1 PF03208.14 EAQ90726.1 - 0.0079 15.5 1.4 0.009 15.3 1.0 1.2 1 0 0 1 1 1 1 PRA1 family protein Shisa PF13908.1 EAQ90726.1 - 0.0084 16.3 4.4 0.011 15.9 3.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF912 PF06024.7 EAQ90726.1 - 0.011 15.7 1.6 0.016 15.2 1.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OSTMP1 PF09777.4 EAQ90726.1 - 0.012 14.7 1.8 0.014 14.5 1.2 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF4448 PF14610.1 EAQ90726.1 - 0.041 13.3 0.4 0.047 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3040 PF11239.3 EAQ90726.1 - 0.043 13.8 6.8 0.066 13.2 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Anoctamin PF04547.7 EAQ90726.1 - 0.069 11.7 0.9 0.079 11.5 0.6 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel HemY_N PF07219.8 EAQ90726.1 - 0.085 12.4 8.8 0.16 11.5 6.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF3357 PF11837.3 EAQ90726.1 - 0.095 12.5 2.5 0.16 11.8 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 EAQ90726.1 - 0.29 10.8 3.6 0.49 10.0 2.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.11 EAQ90726.1 - 0.3 9.2 4.5 0.34 9.1 3.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4389 PF14333.1 EAQ90726.1 - 0.77 9.5 7.8 1.2 8.8 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) gpUL132 PF11359.3 EAQ90726.1 - 2.3 7.4 5.4 2.8 7.2 3.8 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 DUF1049 PF06305.6 EAQ90726.1 - 2.3 7.7 8.0 1.1 8.8 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TMEM210 PF15195.1 EAQ90726.1 - 2.9 8.0 9.7 4 7.5 6.7 1.2 1 0 0 1 1 1 0 TMEM210 family Protocadherin PF08374.6 EAQ90726.1 - 4.3 6.9 9.4 5.8 6.4 6.5 1.1 1 0 0 1 1 1 0 Protocadherin DUF1700 PF08006.6 EAQ90726.1 - 5 6.3 6.5 7.1 5.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Foamy_virus_ENV PF03408.9 EAQ90726.1 - 7.7 3.8 8.8 9.3 3.6 6.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein SCA7 PF08313.7 EAQ90728.1 - 5.5e-31 106.0 0.1 3.7e-30 103.3 0.0 1.9 1 1 1 2 2 2 1 SCA7, zinc-binding domain DUF3176 PF11374.3 EAQ90729.1 - 3.4e-31 107.3 1.9 4.2e-31 107.0 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) zf-C2H2 PF00096.21 EAQ90731.1 - 3.5e-05 23.8 11.0 0.014 15.6 2.0 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ90731.1 - 0.00011 22.2 17.7 0.019 15.2 1.8 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger DUF3450 PF11932.3 EAQ90731.1 - 0.0063 15.8 3.9 0.011 15.0 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Atg14 PF10186.4 EAQ90731.1 - 0.021 13.8 1.0 0.033 13.1 0.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 EAQ90731.1 - 0.13 11.9 0.8 0.3 10.8 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper GBP_C PF02841.9 EAQ90731.1 - 0.2 10.7 5.8 0.3 10.2 4.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TMF_DNA_bd PF12329.3 EAQ90731.1 - 1.8 8.4 7.1 0.25 11.1 2.0 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PALP PF00291.20 EAQ90732.1 - 3.7e-20 72.3 0.4 3.9e-15 55.8 0.1 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 EAQ90733.1 - 5.9e-32 110.7 33.2 5.9e-32 110.7 23.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ90733.1 - 0.00046 18.8 19.1 0.0014 17.2 13.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.11 EAQ90733.1 - 0.0012 18.3 2.5 0.0012 18.3 1.7 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PQ-loop PF04193.9 EAQ90737.1 - 2.9e-31 106.7 14.0 1.4e-15 56.5 2.6 2.6 2 0 0 2 2 2 2 PQ loop repeat Trs65 PF12735.2 EAQ90738.1 - 4.6 6.4 6.9 0.63 9.2 1.9 1.6 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 Mito_carr PF00153.22 EAQ90739.1 - 3.1e-73 241.5 0.5 6.8e-26 89.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EAQ90739.1 - 3.7e-16 57.1 0.1 6.8e-07 28.1 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EAQ90739.1 - 1.3e-13 49.5 3.4 4.6e-05 22.9 0.0 5.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EAQ90739.1 - 2.1e-13 50.2 2.6 4.5e-06 26.6 0.0 3.9 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 EAQ90739.1 - 6.7e-12 44.8 0.2 0.01 15.4 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EAQ90739.1 - 1e-11 43.5 0.6 4.4e-07 28.9 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.1 EAQ90739.1 - 0.043 13.4 0.3 7.3 6.3 0.0 3.4 3 1 0 3 3 3 0 EF hand Cyclin_N PF00134.18 EAQ90740.1 - 1.2e-42 144.4 0.3 2.4e-42 143.4 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAQ90740.1 - 9e-32 109.4 0.0 2.7e-31 107.9 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EAQ90742.1 - 0.002 17.9 12.3 0.0035 17.2 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EAQ90744.1 - 2.3e-14 53.2 0.0 1.9e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAQ90744.1 - 5.6e-11 41.9 4.0 3.5e-06 26.1 0.3 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAQ90744.1 - 2.6e-06 27.4 0.0 1.1e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAQ90744.1 - 1.2e-05 24.4 0.2 0.0052 15.7 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EAQ90744.1 - 2.2e-05 23.0 0.5 0.011 14.1 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EAQ90744.1 - 0.00031 21.0 0.2 0.4 11.1 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ90744.1 - 0.00035 19.5 1.0 0.00058 18.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAQ90744.1 - 0.00068 19.6 0.1 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ90744.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EAQ90744.1 - 0.044 12.8 0.7 3.9 6.4 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EAQ90744.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A RNA_pol_Rpc4 PF05132.9 EAQ90745.1 - 1.3e-24 86.6 0.0 1.3e-24 86.6 0.0 3.0 3 1 0 3 3 3 1 RNA polymerase III RPC4 Imm6 PF14434.1 EAQ90745.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 Hamartin PF04388.7 EAQ90745.1 - 0.68 8.5 3.0 0.85 8.2 2.1 1.1 1 0 0 1 1 1 0 Hamartin protein CAF-1_p150 PF11600.3 EAQ90745.1 - 9.3 5.5 15.6 0.017 14.4 3.4 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UreD PF01774.12 EAQ90746.1 - 3e-58 196.7 0.4 9.6e-56 188.5 0.0 2.4 2 0 0 2 2 2 2 UreD urease accessory protein STAG PF08514.6 EAQ90746.1 - 3.7e-30 104.0 0.3 1.2e-29 102.3 0.2 1.9 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EAQ90746.1 - 3.1e-05 24.1 0.0 0.0046 17.1 0.0 3.5 2 1 1 3 3 3 2 HEAT repeats POT1 PF02765.12 EAQ90747.1 - 1.6e-18 67.0 0.0 3.6e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EAQ90747.1 - 3.5e-06 26.7 0.1 0.0022 17.7 0.0 3.1 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain Arm PF00514.18 EAQ90748.1 - 1.5e-95 310.1 14.4 6.7e-14 51.1 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAQ90748.1 - 3.6e-26 91.2 0.1 4.6e-11 42.8 0.0 5.6 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EAQ90748.1 - 2e-23 82.1 8.9 5.4e-10 39.4 0.0 6.1 5 1 2 7 7 6 3 HEAT-like repeat IBB PF01749.15 EAQ90748.1 - 3.3e-23 81.6 0.8 5.7e-23 80.8 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EAQ90748.1 - 8.4e-22 75.2 1.2 6.9e-07 28.8 0.0 7.2 8 0 0 8 8 7 4 HEAT repeat Arm_2 PF04826.8 EAQ90748.1 - 1.1e-10 41.0 0.0 0.01 14.9 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EAQ90748.1 - 5e-06 25.1 0.0 0.00023 19.6 0.0 2.5 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EAQ90748.1 - 0.00015 21.6 0.0 1.2 9.1 0.0 4.4 2 1 3 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 EAQ90748.1 - 0.00035 20.7 0.6 0.46 11.0 0.0 4.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EAQ90748.1 - 0.00087 17.6 0.7 0.2 9.9 0.0 3.2 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 EAQ90748.1 - 0.029 13.9 0.0 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain SURF6 PF04935.7 EAQ90748.1 - 3 7.0 8.3 4.5 6.4 5.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 HA2 PF04408.18 EAQ90749.1 - 3.5e-20 71.9 1.6 7.5e-20 70.8 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAQ90749.1 - 2.2e-14 53.0 0.0 5.8e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EAQ90749.1 - 1.8e-13 50.2 0.0 8.1e-13 48.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EAQ90749.1 - 2.2e-09 37.0 0.3 6.9e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA PF00627.26 EAQ90749.1 - 2.9e-05 23.7 2.0 0.0008 19.1 0.0 3.1 3 0 0 3 3 2 1 UBA/TS-N domain RWD PF05773.17 EAQ90749.1 - 5.8e-05 22.9 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 EAQ90749.1 - 0.00043 20.4 0.1 0.0012 19.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ90749.1 - 0.00058 19.5 0.1 0.0026 17.4 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EAQ90749.1 - 0.005 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EAQ90749.1 - 0.012 14.6 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 EAQ90749.1 - 0.02 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EAQ90749.1 - 0.034 14.4 0.1 0.084 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain DND1_DSRM PF14709.1 EAQ90749.1 - 0.047 13.9 0.0 0.047 13.9 0.0 2.4 3 0 0 3 3 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_25 PF13481.1 EAQ90749.1 - 0.052 12.9 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 EAQ90749.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF258 PF03193.11 EAQ90749.1 - 0.22 10.7 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AT_hook PF02178.14 EAQ90750.1 - 0.24 11.1 54.4 0.13 12.0 2.9 5.5 5 0 0 5 5 5 0 AT hook motif ICE2 PF08426.5 EAQ90751.1 - 2e-104 349.4 8.0 3.3e-52 177.5 3.6 2.0 1 1 1 2 2 2 2 ICE2 WI12 PF07107.6 EAQ90753.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Wound-induced protein WI12 XylR_N PF06505.6 EAQ90753.1 - 0.098 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism Snf7 PF03357.16 EAQ90754.1 - 1.2e-32 112.6 17.3 1.2e-32 112.6 12.0 2.0 1 1 1 2 2 2 1 Snf7 Fmp27_WPPW PF10359.4 EAQ90754.1 - 0.031 12.7 7.4 0.042 12.2 5.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MutS_III PF05192.13 EAQ90754.1 - 0.046 13.4 2.4 0.052 13.3 1.4 1.3 1 1 0 1 1 1 0 MutS domain III XkdN PF08890.6 EAQ90754.1 - 0.13 12.0 6.8 0.044 13.5 2.2 2.0 1 1 1 2 2 2 0 Phage XkdN-like protein TMCO5 PF14992.1 EAQ90754.1 - 0.15 11.1 15.3 0.47 9.5 10.2 1.7 1 1 1 2 2 2 0 TMCO5 family CK2S PF15011.1 EAQ90754.1 - 0.18 11.5 5.4 2 8.1 1.2 2.4 1 1 1 2 2 2 0 Casein Kinase 2 substrate GTPase_Cys_C PF12631.2 EAQ90754.1 - 0.18 12.1 1.2 0.48 10.8 0.2 2.2 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Misat_Tub_SegII PF10644.4 EAQ90754.1 - 0.22 11.5 4.6 0.1 12.6 0.9 2.1 1 1 1 2 2 2 0 Misato Segment II tubulin-like domain DUF2433 PF10360.4 EAQ90754.1 - 0.29 11.4 4.2 0.32 11.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) IFT57 PF10498.4 EAQ90754.1 - 1.2 7.7 15.7 0.28 9.8 6.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TMPIT PF07851.8 EAQ90754.1 - 2.7 6.9 5.4 3.6 6.5 3.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3138 PF11336.3 EAQ90754.1 - 2.8 6.0 5.1 1.4 7.0 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Translin PF01997.11 EAQ90756.1 - 2.6e-37 128.3 0.4 1.7e-36 125.7 0.3 1.9 1 1 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EAQ90756.1 - 0.011 15.4 0.1 0.13 11.9 0.0 2.3 2 1 0 2 2 2 0 GMP synthase C terminal domain PIG-F PF06699.6 EAQ90757.1 - 1.1e-60 204.9 1.9 1.3e-60 204.6 1.3 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF1761 PF08570.5 EAQ90757.1 - 0.46 10.4 5.0 0.22 11.5 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) Ribosomal_L22e PF01776.12 EAQ90758.1 - 1.3e-46 157.2 0.6 1.6e-46 156.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Pmp3 PF01679.12 EAQ90759.1 - 1.7e-16 59.6 1.8 1.8e-16 59.5 1.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RVT_1 PF00078.22 EAQ90760.1 - 1.4e-22 80.0 0.0 2.5e-21 76.0 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ90760.1 - 0.0002 20.9 0.0 0.00054 19.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Myb_DNA-bind_3 PF12776.2 EAQ90761.1 - 1.8e-05 25.2 0.0 3.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MULE PF10551.4 EAQ90762.1 - 1.4e-15 57.2 0.1 5.2e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 EAQ90762.1 - 0.0026 16.3 0.0 0.0048 15.4 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.4 EAQ90763.1 - 1.6e-19 69.8 0.4 1e-18 67.2 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain DDE_3 PF13358.1 EAQ90763.1 - 2.3e-16 59.8 0.3 5.9e-16 58.5 0.2 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EAQ90763.1 - 7.1e-14 51.6 2.9 7.1e-14 51.6 2.0 1.8 2 0 0 2 2 1 1 Transposase HTH_29 PF13551.1 EAQ90763.1 - 4.6e-10 39.6 1.9 1.8e-09 37.7 1.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix Transposase_mut PF00872.13 EAQ90763.1 - 1.1e-05 24.1 0.2 0.00011 20.8 0.0 2.1 2 0 0 2 2 2 1 Transposase, Mutator family HTH_28 PF13518.1 EAQ90763.1 - 0.00096 19.1 1.7 0.0066 16.4 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EAQ90763.1 - 0.0013 18.3 0.2 0.0013 18.3 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EAQ90763.1 - 0.0028 18.3 0.9 0.015 16.1 0.6 2.4 1 0 0 1 1 1 1 Homeodomain-like domain DBD_Tnp_Mut PF03108.10 EAQ90763.1 - 0.035 13.6 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 MuDR family transposase rve PF00665.21 EAQ90763.1 - 0.038 14.0 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain HTH_7 PF02796.10 EAQ90763.1 - 0.074 12.9 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase XkdW PF09636.5 EAQ90763.1 - 0.089 12.6 0.8 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 XkdW protein Helicase_C PF00271.26 EAQ90766.1 - 2.7e-10 39.9 0.3 7.3e-10 38.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ90766.1 - 0.00021 20.8 0.0 0.00048 19.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ90766.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DDE_1 PF03184.14 EAQ90768.1 - 3.2e-45 153.9 0.0 6.2e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ90768.1 - 1.3e-13 50.2 0.0 2.6e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ90768.1 - 4e-05 23.3 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ90768.1 - 0.031 14.2 0.7 0.08 12.8 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D DDE_1 PF03184.14 EAQ90771.1 - 3.6e-17 62.2 0.0 6.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ90771.1 - 0.0023 17.6 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Prominin PF05478.6 EAQ90771.1 - 0.16 9.4 0.2 0.22 9.0 0.1 1.1 1 0 0 1 1 1 0 Prominin RVT_1 PF00078.22 EAQ90772.1 - 4.7e-20 71.8 0.0 1.2e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ90772.1 - 3e-17 62.8 0.0 1.1e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ90772.1 - 1.3e-07 31.1 0.5 4.5e-07 29.4 0.3 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EAQ90772.1 - 0.00014 21.6 2.3 0.0004 20.1 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EAQ90772.1 - 0.023 14.7 0.1 0.023 14.7 0.1 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein DUF501 PF04417.7 EAQ90772.1 - 0.13 12.0 1.0 0.38 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF972 PF06156.8 EAQ90772.1 - 0.17 12.2 3.5 0.58 10.5 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nup88 PF10168.4 EAQ90772.1 - 0.29 8.9 2.4 0.47 8.2 1.7 1.2 1 0 0 1 1 1 0 Nuclear pore component Atg14 PF10186.4 EAQ90772.1 - 0.3 9.9 2.8 0.64 8.9 1.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MMS22L_C PF14911.1 EAQ90772.1 - 0.65 8.9 1.3 1.2 8.0 0.9 1.4 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal RVT_1 PF00078.22 EAQ90773.1 - 2.4e-41 141.4 0.0 2.6e-39 134.7 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TBD PF12845.2 EAQ90773.1 - 0.056 12.9 0.8 4.2 6.9 0.0 2.9 3 0 0 3 3 3 0 TBD domain DUF45 PF01863.12 EAQ90773.1 - 0.24 11.1 3.7 0.43 10.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Helitron_like_N PF14214.1 EAQ90775.1 - 2.1e-30 105.8 0.1 4.9e-26 91.5 0.0 2.5 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EAQ90775.1 - 4.1e-26 91.7 0.0 6.2e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ90775.1 - 3e-07 30.1 0.0 5.3e-06 26.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ90775.1 - 0.00015 21.4 0.1 0.00046 19.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EAQ90775.1 - 0.00025 18.9 0.0 0.0028 15.5 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EAQ90775.1 - 0.017 15.2 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Torsin PF06309.6 EAQ90775.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Torsin UCH PF00443.24 EAQ90776.1 - 3.1e-38 131.4 0.0 7.2e-37 126.9 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ90776.1 - 1.2e-08 34.7 0.2 4.2e-05 23.1 0.1 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.13 EAQ90777.1 - 2.5e-87 292.6 0.0 3.1e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein GFO_IDH_MocA PF01408.17 EAQ90778.1 - 9.9e-14 51.8 0.0 2.7e-13 50.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAQ90778.1 - 5.7e-05 22.8 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain RNase_T PF00929.19 EAQ90780.1 - 5.3e-13 49.5 0.0 5.2e-10 39.8 0.0 2.9 2 1 0 2 2 2 2 Exonuclease PGM_PMM_I PF02878.11 EAQ90781.1 - 2.5e-33 114.5 0.0 3.6e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EAQ90781.1 - 1.2e-24 86.4 0.0 2.7e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EAQ90781.1 - 2.5e-16 59.9 0.0 5.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EAQ90781.1 - 9e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Archaeal_AmoA PF12942.2 EAQ90781.1 - 0.13 11.9 0.1 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) HMG_box PF00505.14 EAQ90783.1 - 9.7e-26 89.8 0.8 1.6e-25 89.1 0.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ90783.1 - 3.3e-19 69.0 1.3 5.5e-19 68.3 0.9 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EAQ90783.1 - 0.002 17.8 0.4 0.002 17.8 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EAQ90783.1 - 0.018 15.2 0.1 0.039 14.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 EAQ90783.1 - 0.17 12.1 1.4 0.24 11.6 0.2 1.8 1 1 1 2 2 2 0 Cold shock protein DEAD box A ATG11 PF10377.4 EAQ90785.1 - 5.1e-36 123.4 0.0 5.1e-36 123.4 0.0 3.0 3 0 0 3 3 3 1 Autophagy-related protein 11 Tropomyosin PF00261.15 EAQ90785.1 - 0.00049 19.2 5.6 0.00049 19.2 3.9 5.2 3 2 0 3 3 3 1 Tropomyosin APG17 PF04108.7 EAQ90785.1 - 0.014 14.1 0.3 0.014 14.1 0.2 4.1 3 1 1 4 4 4 0 Autophagy protein Apg17 Reo_sigmaC PF04582.7 EAQ90785.1 - 1.4 7.9 19.9 0.74 8.9 2.9 4.5 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Filament PF00038.16 EAQ90785.1 - 2.8 7.3 54.4 52 3.1 29.1 4.5 2 1 1 3 3 3 0 Intermediate filament protein AATase PF07247.7 EAQ90786.1 - 1.8e-17 63.0 0.0 6.5e-17 61.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Ribosomal_L9_N PF01281.14 EAQ90786.1 - 1.3e-05 24.3 0.0 2.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Condensation PF00668.15 EAQ90786.1 - 0.06 12.1 0.0 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Condensation domain LSM PF01423.17 EAQ90789.1 - 6.3e-17 60.8 0.1 7.8e-17 60.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAQ90789.1 - 9.9e-05 22.1 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SPAN PF02510.9 EAQ90789.1 - 0.087 11.8 0.0 0.093 11.7 0.0 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein HSP20 PF00011.16 EAQ90790.1 - 2e-16 59.6 0.0 3e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family YTH PF04146.10 EAQ90791.1 - 4.1e-55 185.2 0.0 5.4e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 YT521-B-like domain Rav1p_C PF12234.3 EAQ90791.1 - 0.15 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal Proteasome PF00227.21 EAQ90792.1 - 2.6e-28 98.5 0.2 7.1e-28 97.1 0.1 1.7 1 1 1 2 2 2 1 Proteasome subunit PI3_PI4_kinase PF00454.22 EAQ90793.1 - 8.3e-41 139.9 0.0 2.5e-40 138.4 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EAQ90793.1 - 2e-23 82.5 0.1 4.5e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 EAQ90793.1 - 0.014 15.3 0.0 2.6 8.0 0.0 2.9 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Cation_efflux PF01545.16 EAQ90794.1 - 5.1e-23 81.5 4.4 8.1e-20 71.0 1.6 2.1 1 1 1 2 2 2 2 Cation efflux family DMRL_synthase PF00885.14 EAQ90797.1 - 7e-48 161.9 0.0 2.8e-28 98.4 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.1 EAQ90798.1 - 2.2e-13 50.0 0.0 4.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAQ90798.1 - 2.1e-11 43.5 0.0 5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EAQ90798.1 - 1.4e-09 37.4 0.0 2.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TRP PF06011.7 EAQ90799.1 - 1.7e-93 313.5 21.8 1.6e-92 310.4 15.2 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAQ90799.1 - 3.8e-32 111.2 0.2 1.2e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 ML-like domain WD40 PF00400.27 EAQ90802.1 - 5.5e-14 51.4 0.6 0.89 9.5 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat RNA_pol_Rpb4 PF03874.11 EAQ90803.1 - 9.6e-28 96.5 2.4 1.1e-27 96.3 1.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 CPL PF08144.6 EAQ90804.1 - 9.5e-19 67.6 0.0 6e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 CPL (NUC119) domain CTI PF06934.6 EAQ90804.1 - 0.017 13.3 0.1 0.028 12.6 0.1 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) RWD PF05773.17 EAQ90805.1 - 3.5e-25 88.0 0.7 5.6e-25 87.4 0.5 1.3 1 0 0 1 1 1 1 RWD domain Asn_synthase PF00733.16 EAQ90805.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Asparagine synthase FdhE PF04216.7 EAQ90805.1 - 0.46 10.1 2.6 0.59 9.7 1.8 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation KfrA_N PF11740.3 EAQ90805.1 - 2.4 8.6 14.0 3.6 8.0 4.4 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term TPR_12 PF13424.1 EAQ90806.1 - 1.2e-07 31.5 0.9 0.0002 21.2 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ90806.1 - 3.4e-07 30.4 0.5 0.0044 17.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ90806.1 - 2.4e-06 27.0 0.1 0.015 15.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ90806.1 - 5.6e-06 26.8 9.9 0.0002 21.9 0.6 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ90806.1 - 6.2e-05 22.5 0.1 0.0031 17.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ90806.1 - 0.00031 20.3 0.0 1.5 8.5 0.0 3.2 3 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 EAQ90806.1 - 0.0017 18.8 10.2 0.072 13.7 0.0 5.5 5 2 2 7 7 7 1 Tetratricopeptide repeat Ring_hydroxyl_B PF00866.13 EAQ90806.1 - 0.012 15.3 0.4 0.025 14.2 0.3 1.5 1 0 0 1 1 1 0 Ring hydroxylating beta subunit TPR_8 PF13181.1 EAQ90806.1 - 0.023 14.4 0.0 0.3 10.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ90806.1 - 0.042 13.4 0.0 0.43 10.2 0.0 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ90806.1 - 0.053 13.7 0.0 82 3.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ90806.1 - 0.11 12.9 0.5 0.11 12.9 0.3 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF2681 PF10883.3 EAQ90806.1 - 0.19 11.9 0.3 0.19 11.9 0.2 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF2681) TPR_9 PF13371.1 EAQ90806.1 - 0.25 11.2 3.3 3.2 7.6 0.0 3.3 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90806.1 - 4.5 7.9 8.8 8.8 7.0 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat CFEM PF05730.6 EAQ90807.1 - 0.00097 18.9 5.3 0.0017 18.1 3.7 1.3 1 0 0 1 1 1 1 CFEM domain Herpes_UL32 PF06070.6 EAQ90807.1 - 1.9 6.8 9.1 2.2 6.6 6.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 MutS_V PF00488.16 EAQ90808.1 - 2.5e-52 177.6 0.0 3.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAQ90808.1 - 2.2e-20 73.2 0.4 4.7e-20 72.2 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MMgT PF10270.4 EAQ90809.1 - 9.5e-34 116.0 0.0 1.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.14 EAQ90810.1 - 1.7e-10 40.9 3.6 4e-10 39.8 2.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EAQ90810.1 - 0.012 14.9 0.1 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 EAQ90810.1 - 0.043 14.1 1.1 0.092 13.1 0.8 1.6 1 0 0 1 1 1 0 HMG-box domain PHD PF00628.24 EAQ90811.1 - 2.9e-08 33.2 9.6 5.2e-08 32.4 6.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EAQ90811.1 - 0.079 12.2 5.8 0.16 11.3 4.0 1.4 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.26 EAQ90812.1 - 7.3e-86 286.5 64.0 2.6e-30 105.1 6.9 6.0 4 1 0 4 4 4 4 Ion transport protein DsrD PF08679.6 EAQ90814.1 - 0.15 12.0 0.6 0.29 11.1 0.4 1.4 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Cyclin_N PF00134.18 EAQ90815.1 - 8.7e-44 148.1 0.1 2.1e-43 146.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAQ90815.1 - 1.4e-32 112.0 0.1 2.7e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 EAQ90816.1 - 5e-31 107.1 0.5 2.2e-30 105.1 0.4 1.9 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain PAP2 PF01569.16 EAQ90817.1 - 9.1e-21 73.8 1.8 9.1e-21 73.8 1.2 2.8 2 2 0 2 2 2 1 PAP2 superfamily CK_II_beta PF01214.13 EAQ90818.1 - 5.2e-66 221.6 0.9 5.5e-36 123.8 0.0 2.1 2 0 0 2 2 2 2 Casein kinase II regulatory subunit RXT2_N PF08595.6 EAQ90818.1 - 0.27 11.0 1.2 0.4 10.4 0.5 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal GST_C_2 PF13410.1 EAQ90819.1 - 0.00051 19.8 0.1 0.0014 18.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ90819.1 - 0.0016 18.4 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RIC1 PF07064.8 EAQ90820.1 - 8.2e-91 304.0 0.0 1.1e-90 303.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EAQ90820.1 - 1.6e-05 24.5 1.0 0.56 10.1 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.27 EAQ90821.1 - 1.3e-13 50.2 0.2 5e-05 23.0 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EAQ90821.1 - 8.2e-10 37.4 0.5 5.3e-05 21.5 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 EAQ90821.1 - 0.013 14.4 0.0 0.027 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) Hira PF07569.6 EAQ90821.1 - 0.047 12.8 0.1 0.34 10.0 0.0 1.9 1 1 1 2 2 2 0 TUP1-like enhancer of split Fungal_trans PF04082.13 EAQ90822.1 - 1.3e-19 70.0 0.1 2.3e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ90822.1 - 1.9e-08 34.0 8.7 1.9e-08 34.0 6.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EAQ90823.1 - 1.9e-16 59.7 13.3 2.2e-11 43.0 9.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Trep_Strep PF09605.5 EAQ90823.1 - 6 6.4 11.4 0.38 10.3 1.6 2.4 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Polysacc_synt_C PF14667.1 EAQ90823.1 - 8.2 6.2 15.0 11 5.8 9.0 2.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.1 EAQ90823.1 - 8.8 5.7 8.5 6.4 6.1 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HTH_23 PF13384.1 EAQ90824.1 - 6e-06 25.7 1.5 0.00032 20.2 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.11 EAQ90824.1 - 0.0033 16.7 0.3 0.2 11.0 0.1 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_24 PF13412.1 EAQ90824.1 - 0.01 15.2 0.6 0.058 12.8 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EAQ90824.1 - 0.013 15.0 0.3 0.013 15.0 0.2 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EAQ90824.1 - 0.017 15.1 0.9 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 Transposase HTH_11 PF08279.7 EAQ90824.1 - 0.055 13.1 0.2 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 HTH domain HTH_29 PF13551.1 EAQ90824.1 - 0.16 12.1 2.4 1.5 9.0 0.0 2.7 2 1 0 2 2 2 0 Winged helix-turn helix Acetate_kinase PF00871.12 EAQ90825.1 - 2.8e-81 273.0 0.0 2.5e-67 227.1 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family Trypan_PARP PF05887.6 EAQ90825.1 - 0.0076 16.0 2.1 0.0076 16.0 1.4 1.6 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 EAQ90825.1 - 0.076 12.1 16.4 0.12 11.4 11.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neisseria_TspB PF05616.8 EAQ90825.1 - 4.7 5.4 9.0 7.4 4.8 6.2 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-C2H2_4 PF13894.1 EAQ90826.1 - 0.00084 19.5 5.7 0.0016 18.6 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ90826.1 - 0.0011 19.1 3.1 0.0011 19.1 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ90826.1 - 0.0033 17.6 8.8 0.0087 16.3 1.2 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type Integrin_B_tail PF07965.7 EAQ90826.1 - 0.073 13.5 0.8 0.18 12.2 0.1 1.8 1 1 1 2 2 2 0 Integrin beta tail domain zf-met PF12874.2 EAQ90826.1 - 0.27 11.5 1.7 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Prp31_C PF09785.4 EAQ90829.1 - 5.2e-41 139.9 0.3 1.2e-40 138.8 0.2 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EAQ90829.1 - 1.3e-39 134.9 0.1 2.1e-39 134.1 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EAQ90829.1 - 1.5e-22 79.1 0.0 2.2e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain HAT PF02184.11 EAQ90830.1 - 5.3e-24 83.6 63.4 4.3e-11 42.3 0.3 12.7 14 0 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EAQ90830.1 - 5.2e-23 79.4 24.4 9.5e-06 25.8 0.1 11.7 8 2 5 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ90830.1 - 1.9e-20 72.9 4.4 2.3e-07 31.0 0.0 8.0 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ90830.1 - 1.2e-19 70.3 8.8 0.025 15.2 0.2 8.6 8 1 0 9 9 8 4 Tetratricopeptide repeat Suf PF05843.9 EAQ90830.1 - 3.4e-16 59.8 11.3 2.7e-05 24.0 0.0 6.7 3 1 4 7 7 7 3 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EAQ90830.1 - 4.5e-08 32.4 10.7 0.0033 16.5 0.2 5.4 2 1 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ90830.1 - 1.1e-07 31.7 14.6 0.75 9.7 0.0 8.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90830.1 - 4.7e-06 26.6 18.4 0.18 12.3 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAQ90830.1 - 2.9e-05 23.8 3.9 0.46 10.3 0.0 5.6 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 EAQ90830.1 - 5.8e-05 22.6 10.0 0.011 15.3 0.1 5.7 6 1 0 6 6 6 2 TPR repeat TPR_17 PF13431.1 EAQ90830.1 - 0.0022 18.0 8.0 2.3 8.6 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EAQ90830.1 - 0.0072 16.0 15.8 0.031 14.0 1.4 5.6 3 2 1 5 5 5 1 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 EAQ90830.1 - 0.0075 16.1 0.1 0.0075 16.1 0.1 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ90830.1 - 0.0076 15.9 0.1 35 4.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ90830.1 - 0.022 14.5 11.7 17 5.5 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ90830.1 - 0.045 13.3 4.4 3.1 7.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EAQ90830.1 - 0.048 13.7 2.4 1.7 8.8 0.1 3.9 3 0 0 3 3 3 0 c-SKI Smad4 binding domain TPR_9 PF13371.1 EAQ90830.1 - 0.073 12.9 5.7 17 5.3 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Patatin PF01734.17 EAQ90830.1 - 0.23 11.3 0.0 0.68 9.8 0.0 1.9 1 0 0 1 1 1 0 Patatin-like phospholipase NRDE-2 PF08424.5 EAQ90830.1 - 0.41 9.4 27.5 0.47 9.2 0.9 5.7 4 2 1 6 6 6 0 NRDE-2, necessary for RNA interference Spore_III_AB PF09548.5 EAQ90830.1 - 0.67 9.6 4.7 2.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Corona_nucleoca PF00937.13 EAQ90831.1 - 0.0049 15.8 5.9 0.0049 15.8 4.1 4.4 4 1 1 5 5 5 3 Coronavirus nucleocapsid protein HLH PF00010.21 EAQ90832.1 - 2.1e-05 24.0 0.2 4.1e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain La PF05383.12 EAQ90833.1 - 6e-15 54.7 0.0 1.1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 La domain NPR3 PF03666.8 EAQ90837.1 - 2.5e-137 458.1 3.5 2.9e-137 457.8 0.0 2.4 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_LMP1 PF05297.6 EAQ90837.1 - 2.4 6.9 14.4 5.1 5.9 10.0 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Choline_kinase PF01633.15 EAQ90838.1 - 1.2e-55 188.3 0.0 5.7e-55 186.1 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EAQ90838.1 - 1.2e-11 44.8 0.1 3.8e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EAQ90838.1 - 0.16 11.0 0.0 8.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase GCV_T PF01571.16 EAQ90839.1 - 3.4e-60 203.0 0.0 4.9e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EAQ90839.1 - 2.5e-24 85.1 1.2 6.3e-24 83.8 0.8 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain HA2 PF04408.18 EAQ90840.1 - 1.2e-25 89.4 0.1 5.3e-25 87.3 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAQ90840.1 - 1.1e-23 83.2 0.0 7.1e-23 80.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAQ90840.1 - 1.5e-12 47.1 0.0 4.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ90840.1 - 1.7e-08 34.1 0.1 3.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAQ90840.1 - 0.00012 22.2 0.1 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EAQ90840.1 - 0.00033 20.5 0.0 0.055 13.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EAQ90840.1 - 0.0022 16.9 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EAQ90840.1 - 0.0037 16.2 0.0 0.0066 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 EAQ90840.1 - 0.0044 16.7 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 EAQ90840.1 - 0.0055 16.1 0.3 0.013 14.9 0.2 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 EAQ90840.1 - 0.032 13.3 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EAQ90840.1 - 0.042 13.7 0.4 0.43 10.4 0.3 2.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAQ90840.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EAQ90840.1 - 0.058 12.8 0.4 9.3 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EAQ90840.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EAQ90840.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EAQ90840.1 - 0.25 10.9 1.6 0.57 9.8 0.1 2.3 3 0 0 3 3 3 0 NACHT domain WD40 PF00400.27 EAQ90841.1 - 2e-23 81.3 10.3 2e-06 27.4 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EAQ90841.1 - 0.00058 18.1 0.0 0.0023 16.1 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAQ90841.1 - 0.027 13.2 0.0 0.74 8.4 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Hep_59 PF07052.6 EAQ90844.1 - 5.9e-21 74.7 0.1 5.9e-21 74.7 0.1 2.2 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Herpes_gE PF02480.11 EAQ90845.1 - 0.0025 16.1 0.0 0.0034 15.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EAQ90845.1 - 0.014 14.6 1.4 0.035 13.4 1.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF846 PF05832.7 EAQ90846.1 - 2.4e-47 160.2 5.7 3e-47 159.8 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HpcH_HpaI PF03328.9 EAQ90847.1 - 6.6e-41 139.6 0.6 6.6e-41 139.6 0.4 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EAQ90847.1 - 7.3e-15 54.6 0.3 3.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold RRM_1 PF00076.17 EAQ90849.1 - 4.2e-20 71.1 0.0 5.9e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ90849.1 - 1e-12 47.8 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ90849.1 - 5.5e-08 32.5 0.0 7.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fox-1_C PF12414.3 EAQ90849.1 - 0.0055 17.0 3.0 0.0079 16.5 2.1 1.4 1 0 0 1 1 1 1 Calcitonin gene-related peptide regulator C terminal ChaC PF04752.7 EAQ90850.1 - 1.7e-35 122.5 0.0 2.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 EAQ90851.1 - 3.5e-26 88.4 7.1 1e-06 27.5 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EAQ90851.1 - 1.6e-23 82.5 6.7 2.7e-09 37.0 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EAQ90851.1 - 8.7e-22 75.0 6.7 0.0001 21.8 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EAQ90851.1 - 2.2e-19 68.7 11.5 6.7e-10 38.4 0.0 5.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 EAQ90851.1 - 6.2e-18 63.2 9.1 5.9e-05 22.2 0.3 4.6 4 0 0 4 4 4 4 EF hand 2OG-FeII_Oxy PF03171.15 EAQ90853.1 - 4e-15 55.9 0.0 1.1e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAQ90853.1 - 2.2e-09 37.8 0.0 3.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Atrophin-1 PF03154.10 EAQ90854.1 - 0.16 10.0 1.6 0.2 9.7 1.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Mis14 PF08641.7 EAQ90854.1 - 0.31 11.1 2.9 0.89 9.6 2.0 1.7 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Zip PF02535.17 EAQ90855.1 - 0.38 9.7 5.5 0.58 9.1 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AUX_IAA PF02309.11 EAQ90855.1 - 1.2 8.8 6.4 2.6 7.7 4.5 1.6 1 0 0 1 1 1 0 AUX/IAA family SelP_N PF04592.9 EAQ90855.1 - 2.5 7.4 14.7 4.1 6.7 10.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Rad51 PF08423.6 EAQ90856.1 - 2.9e-136 452.3 0.0 3.7e-136 452.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAQ90856.1 - 1.4e-13 50.7 0.0 2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EAQ90856.1 - 7.6e-09 35.6 0.8 1.8e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 EAQ90856.1 - 1.5e-06 27.5 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EAQ90856.1 - 1.5e-05 24.2 0.0 2.8e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EAQ90856.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EAQ90856.1 - 0.096 11.5 0.1 0.25 10.1 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Lyase_8_C PF02884.12 EAQ90856.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain HHH_6 PF14579.1 EAQ90856.1 - 0.14 12.1 0.1 9.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Nup160 PF11715.3 EAQ90857.1 - 6.7e-152 506.4 0.0 1.7e-94 316.9 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Strep_SA_rep PF06696.6 EAQ90857.1 - 0.076 12.7 1.0 2.7 7.8 0.1 2.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Vps26 PF03643.10 EAQ90858.1 - 4.5e-131 435.6 0.6 5.3e-131 435.4 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EAQ90858.1 - 0.00014 21.7 0.0 0.41 10.4 0.0 3.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ribosomal_L6 PF00347.18 EAQ90859.1 - 3.3e-26 91.6 7.9 2.4e-13 50.3 2.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 TcdA_TcdB_pore PF12920.2 EAQ90859.1 - 0.02 12.8 0.2 0.025 12.5 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain TMEM51 PF15345.1 EAQ90860.1 - 0.027 14.1 1.9 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF1469 PF07332.6 EAQ90860.1 - 3.4 7.4 8.3 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) V-ATPase_H_N PF03224.9 EAQ90861.1 - 4.2e-38 131.2 0.0 5e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EAQ90862.1 - 3.4e-38 130.2 0.0 7e-38 129.1 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EAQ90862.1 - 5.3e-05 22.4 0.0 7.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H DUF2089 PF09862.4 EAQ90862.1 - 0.095 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HEAT_EZ PF13513.1 EAQ90862.1 - 1.8 9.1 4.3 5.3 7.6 0.1 3.0 2 2 0 2 2 2 0 HEAT-like repeat Acylphosphatase PF00708.13 EAQ90863.1 - 1.8e-08 34.3 0.1 7e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Acylphosphatase BLUF PF04940.7 EAQ90863.1 - 0.026 14.2 0.1 0.036 13.7 0.0 1.3 1 1 0 1 1 1 0 Sensors of blue-light using FAD DUF726 PF05277.7 EAQ90864.1 - 8.2e-92 307.7 0.1 9.7e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 EAQ90864.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ90864.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 EAQ90864.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Cutinase DPM3 PF08285.6 EAQ90864.1 - 0.16 11.8 0.2 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) AlphaC_N PF08829.5 EAQ90864.1 - 0.33 10.2 1.3 0.7 9.2 0.1 1.8 2 0 0 2 2 2 0 Alpha C protein N terminal Fcf1 PF04900.7 EAQ90865.1 - 1e-11 44.8 0.1 2.6e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Fcf1 YL1 PF05764.8 EAQ90865.1 - 0.58 9.7 18.2 0.98 8.9 12.5 1.4 1 1 0 1 1 1 0 YL1 nuclear protein SpoIIE PF07228.7 EAQ90866.1 - 0.00034 20.3 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EAQ90866.1 - 0.0076 15.6 0.0 0.057 12.8 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C PH PF00169.24 EAQ90867.1 - 1.9e-06 27.9 0.0 4.3e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EAQ90867.1 - 0.0012 18.9 0.1 0.006 16.7 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain Pkinase PF00069.20 EAQ90869.1 - 1.7e-66 224.0 0.0 2.5e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ90869.1 - 8.8e-30 103.6 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EAQ90869.1 - 1.2e-09 38.1 0.0 2.9e-07 30.5 0.0 2.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EAQ90869.1 - 0.0026 16.7 0.0 0.0083 15.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ90869.1 - 0.0063 16.2 0.9 1.7 8.3 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EAQ90869.1 - 0.0068 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2413 PF10310.4 EAQ90870.1 - 0.005 15.7 8.5 0.016 14.0 5.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) STT3 PF02516.9 EAQ90871.1 - 5.7e-123 411.4 37.9 2.5e-118 396.1 24.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 EAQ90871.1 - 0.00036 19.9 14.5 0.00036 19.9 10.1 2.8 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cytomega_TRL10 PF06084.6 EAQ90871.1 - 0.08 12.7 0.1 0.27 11.0 0.1 1.9 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Ribosomal_L29 PF00831.18 EAQ90872.1 - 3.5e-18 65.0 0.9 3.5e-18 65.0 0.6 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EAQ90872.1 - 0.0013 18.9 0.6 0.0016 18.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Snapin_Pallidin PF14712.1 EAQ90872.1 - 0.57 10.5 4.1 0.21 11.9 0.7 1.7 1 1 1 2 2 2 0 Snapin/Pallidin FlxA PF14282.1 EAQ90872.1 - 0.59 10.1 2.8 1 9.3 2.0 1.4 1 0 0 1 1 1 0 FlxA-like protein Ribosomal_L6e PF01159.14 EAQ90873.1 - 1.3e-37 128.3 0.3 1.8e-37 127.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Colicin_Pyocin PF01320.13 EAQ90873.1 - 0.2 11.5 1.0 0.62 9.9 0.1 1.9 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein V-SNARE_C PF12352.3 EAQ90874.1 - 1.9e-12 47.0 3.6 1.2e-11 44.4 0.1 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SATase_N PF06426.9 EAQ90874.1 - 0.4 10.9 3.5 0.59 10.4 0.5 2.2 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal ATP-synt_10 PF05176.9 EAQ90875.1 - 8.2e-90 300.4 0.0 1e-89 300.1 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Pertus-S4-tox PF09275.5 EAQ90875.1 - 0.091 12.8 0.1 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S4 subunit 2-oxoacid_dh PF00198.18 EAQ90876.1 - 3.1e-68 229.5 0.0 3.9e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EAQ90876.1 - 4.6e-16 58.2 0.0 9.8e-16 57.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme BEX PF04538.7 EAQ90876.1 - 0.25 11.5 0.3 0.64 10.2 0.0 1.7 2 0 0 2 2 2 0 Brain expressed X-linked like family SKI PF01202.17 EAQ90877.1 - 1.2e-15 57.6 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EAQ90877.1 - 6.4e-12 46.3 0.0 7.8e-12 46.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ90877.1 - 2.4e-11 43.6 0.0 3.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ90877.1 - 1.8e-10 41.2 0.0 3.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAQ90877.1 - 1e-06 28.9 0.0 4.4e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ90877.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EAQ90877.1 - 0.00023 21.2 0.1 0.0017 18.3 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 EAQ90877.1 - 0.00031 19.5 0.0 0.00048 18.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Cytidylate_kin2 PF13189.1 EAQ90877.1 - 0.00097 19.0 0.0 0.022 14.6 0.0 2.3 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_19 PF13245.1 EAQ90877.1 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EAQ90877.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EAQ90877.1 - 0.0022 17.3 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase RNA_helicase PF00910.17 EAQ90877.1 - 0.0024 18.0 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EAQ90877.1 - 0.004 16.8 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 EAQ90877.1 - 0.0066 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EAQ90877.1 - 0.0096 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EAQ90877.1 - 0.0097 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Viral_helicase1 PF01443.13 EAQ90877.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ADK PF00406.17 EAQ90877.1 - 0.013 15.4 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.9 EAQ90877.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CoaE PF01121.15 EAQ90877.1 - 0.023 14.1 0.0 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.7 EAQ90877.1 - 0.025 13.6 0.0 0.045 12.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EAQ90877.1 - 0.026 14.1 0.0 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAQ90877.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EAQ90877.1 - 0.033 13.8 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EAQ90877.1 - 0.035 13.6 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EAQ90877.1 - 0.038 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 EAQ90877.1 - 0.042 13.0 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EAQ90877.1 - 0.053 12.9 0.1 0.085 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EAQ90877.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ90877.1 - 0.082 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EAQ90877.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Peptidase_M49 PF03571.10 EAQ90878.1 - 3.9e-217 721.7 0.0 4.6e-217 721.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 zf-C2H2 PF00096.21 EAQ90879.1 - 5e-15 54.8 18.5 1.4e-05 25.1 0.6 5.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ90879.1 - 2.3e-10 40.0 15.1 0.0035 17.5 0.1 5.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ90879.1 - 7.2e-10 38.6 23.2 8e-06 25.8 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EAQ90879.1 - 1e-05 25.4 7.9 0.059 13.5 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAQ90879.1 - 0.0021 17.8 0.2 0.0021 17.8 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EAQ90879.1 - 0.029 14.0 3.5 3.7 7.3 0.2 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 EAQ90879.1 - 0.081 13.1 2.8 5.7 7.2 0.2 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DEAD PF00270.24 EAQ90881.1 - 7.3e-47 158.9 0.2 3.7e-44 150.1 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ90881.1 - 4.3e-23 80.9 0.0 1e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ90881.1 - 0.0005 19.9 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAQ90881.1 - 0.0023 16.7 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HMG_box PF00505.14 EAQ90882.1 - 4.8e-08 33.1 11.1 8.5e-06 25.9 1.8 3.7 2 1 2 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ90882.1 - 1.2e-07 31.9 10.4 2e-05 24.8 2.2 3.4 2 1 2 4 4 4 2 HMG-box domain Dicty_REP PF05086.7 EAQ90882.1 - 2.4 5.8 9.4 3 5.4 6.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3565 PF12088.3 EAQ90883.1 - 0.35 10.6 3.8 1.3 8.8 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) 3Beta_HSD PF01073.14 EAQ90884.1 - 6e-65 218.7 0.0 7.1e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ90884.1 - 4e-34 118.0 0.4 8.2e-34 117.0 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ90884.1 - 5.5e-17 61.5 0.7 5.6e-14 51.6 0.1 2.1 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EAQ90884.1 - 1.7e-15 56.7 0.1 2.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EAQ90884.1 - 4.7e-12 46.2 0.0 6.9e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EAQ90884.1 - 3.3e-08 32.7 0.3 1.8e-07 30.3 0.3 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EAQ90884.1 - 4.9e-07 29.8 0.3 1.3e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ90884.1 - 6.3e-06 25.9 0.6 1.7e-05 24.5 0.4 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EAQ90884.1 - 8.2e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EAQ90884.1 - 0.0019 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 EAQ90884.1 - 0.006 16.4 0.1 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.11 EAQ90884.1 - 0.006 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RhoGAP PF00620.22 EAQ90885.1 - 1.9e-36 124.9 0.1 1.3e-35 122.2 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EAQ90885.1 - 2.1e-30 104.5 38.2 6.8e-12 45.2 5.4 4.4 4 0 0 4 4 4 4 LIM domain Desulfoferrod_N PF06397.7 EAQ90885.1 - 0.11 11.8 1.2 0.5 9.7 0.1 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2417 PF10329.4 EAQ90886.1 - 2e-86 289.1 3.1 2.7e-86 288.7 2.1 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EAQ90886.1 - 0.00016 21.6 2.6 0.00028 20.8 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Menin PF05053.8 EAQ90887.1 - 0.85 7.7 5.4 1.3 7.1 3.8 1.2 1 0 0 1 1 1 0 Menin UQ_con PF00179.21 EAQ90888.1 - 1.6e-14 53.5 0.1 2.9e-09 36.4 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme AAA PF00004.24 EAQ90889.1 - 6e-16 58.8 0.0 1.5e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAQ90889.1 - 4e-13 49.3 0.0 1e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EAQ90889.1 - 3.6e-12 46.0 0.0 1.5e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.10 EAQ90889.1 - 3.5e-11 42.5 0.0 1.5e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EAQ90889.1 - 9.6e-07 29.0 0.0 9.3e-05 22.5 0.0 2.8 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAQ90889.1 - 1.1e-06 27.8 0.1 3.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ90889.1 - 8.4e-06 25.4 0.0 3.4e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EAQ90889.1 - 1.7e-05 24.9 0.2 0.00094 19.2 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EAQ90889.1 - 2.2e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAQ90889.1 - 8.5e-05 21.8 0.0 0.0054 15.9 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EAQ90889.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EAQ90889.1 - 0.0013 18.2 0.2 0.037 13.4 0.0 2.4 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 EAQ90889.1 - 0.0014 18.2 0.0 0.076 12.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EAQ90889.1 - 0.0016 17.4 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 EAQ90889.1 - 0.0022 16.9 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EAQ90889.1 - 0.0027 18.4 0.0 0.0066 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EAQ90889.1 - 0.0029 17.2 0.3 0.0075 15.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EAQ90889.1 - 0.0049 16.4 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 EAQ90889.1 - 0.005 16.5 0.1 0.033 13.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EAQ90889.1 - 0.0058 16.0 0.0 0.028 13.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ90889.1 - 0.0086 15.9 0.0 0.053 13.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAQ90889.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ90889.1 - 0.021 15.1 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EAQ90889.1 - 0.048 12.3 0.0 0.54 8.9 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_10 PF12846.2 EAQ90889.1 - 0.054 12.9 0.2 1.4 8.2 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain AAA_3 PF07726.6 EAQ90889.1 - 0.064 12.8 0.0 0.41 10.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPL PF08144.6 EAQ90889.1 - 0.068 13.0 1.0 0.23 11.3 0.2 2.0 1 1 1 2 2 2 0 CPL (NUC119) domain ResIII PF04851.10 EAQ90889.1 - 0.078 12.8 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EAQ90889.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SNF2_N PF00176.18 EAQ90889.1 - 0.11 11.2 0.0 2.6 6.7 0.0 2.3 2 0 0 2 2 2 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 EAQ90889.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Exonuc_VII_S PF02609.11 EAQ90890.1 - 0.053 13.2 0.4 0.053 13.2 0.3 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF948 PF06103.6 EAQ90890.1 - 0.075 12.9 2.6 21 5.0 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec63 PF02889.11 EAQ90891.1 - 1.8e-193 641.7 0.9 8.3e-110 366.8 0.0 2.7 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EAQ90891.1 - 4.3e-56 189.0 0.1 6.1e-31 107.1 0.0 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EAQ90891.1 - 9.3e-21 74.4 0.0 1.2e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAQ90891.1 - 9.4e-12 44.6 0.0 2.9e-10 39.8 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAQ90891.1 - 3.6e-07 30.3 0.0 0.0094 16.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 EAQ90891.1 - 8.7e-06 24.8 0.0 0.07 12.0 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_10 PF12846.2 EAQ90891.1 - 0.0013 18.2 0.4 4.8 6.5 0.0 4.6 5 1 1 6 6 6 1 AAA-like domain PhoH PF02562.11 EAQ90891.1 - 0.0018 17.5 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 EAQ90891.1 - 0.0051 16.5 0.0 0.3 10.8 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EAQ90891.1 - 0.0058 16.1 0.0 4.9 6.5 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family DUF3335 PF11814.3 EAQ90891.1 - 0.031 13.4 0.4 5.5 6.0 0.0 3.2 3 0 0 3 3 3 0 Peptidase_C39 like family PWWP PF00855.12 EAQ90892.1 - 1e-12 48.0 0.0 1e-12 48.0 0.0 2.9 3 0 0 3 3 3 1 PWWP domain ORC3_N PF07034.6 EAQ90893.1 - 1.2e-31 109.9 0.4 2.8e-31 108.7 0.3 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Sec66 PF09802.4 EAQ90894.1 - 1.1e-82 276.0 0.3 1.3e-82 275.7 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4456 PF14644.1 EAQ90894.1 - 0.029 13.5 0.6 0.043 13.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) FUSC PF04632.7 EAQ90894.1 - 0.11 10.9 0.8 0.14 10.6 0.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 EAQ90894.1 - 0.23 11.7 1.1 0.44 10.9 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EAQ90894.1 - 0.46 9.3 2.8 0.59 9.0 2.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF572 PF04502.8 EAQ90894.1 - 1.4 8.0 9.9 3.5 6.7 7.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF3649 PF12365.3 EAQ90894.1 - 1.9 8.0 4.4 7.5 6.1 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Vfa1 PF08432.5 EAQ90894.1 - 7.8 6.4 8.2 15 5.5 5.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPL4 PF05021.10 EAQ90895.1 - 6.6e-131 436.0 0.0 8.3e-131 435.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EAQ90895.1 - 6.7e-72 239.9 0.1 1.1e-71 239.2 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EAQ90895.1 - 0.053 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 EAQ90895.1 - 0.27 11.0 1.8 0.75 9.5 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) CPSase_L_D2 PF02786.12 EAQ90896.1 - 2.3e-111 370.1 0.1 4.4e-85 284.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EAQ90896.1 - 2.7e-42 143.3 0.1 7.1e-42 142.0 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EAQ90896.1 - 4.4e-38 130.8 0.0 7.9e-21 74.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EAQ90896.1 - 1.4e-35 121.7 0.0 4.7e-17 62.0 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EAQ90896.1 - 1.1e-25 90.1 0.0 3.3e-09 35.9 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EAQ90896.1 - 2.8e-23 82.1 0.0 1.1e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAQ90896.1 - 2.2e-19 69.6 1.0 5.5e-10 38.9 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EAQ90896.1 - 1.8e-09 37.3 0.1 7e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EAQ90896.1 - 2.6e-07 30.3 0.2 0.014 14.9 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EAQ90896.1 - 7.1e-07 29.2 0.2 0.047 13.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 EAQ90896.1 - 0.0003 20.0 0.1 0.048 12.8 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 EAQ90896.1 - 0.057 13.3 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 MGS-like domain DUF1746 PF08508.5 EAQ90897.1 - 1.6e-42 144.0 1.8 2.3e-42 143.6 1.2 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC PF01137.16 EAQ90898.1 - 7.1e-31 106.7 0.0 1.1e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EAQ90898.1 - 7.9e-31 106.1 0.1 1.6e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.1 EAQ90899.1 - 2e-11 43.6 0.0 1.5e-06 28.0 0.0 5.7 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.1 EAQ90899.1 - 5.1e-06 26.3 5.3 0.39 11.1 0.0 7.0 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR PF01535.15 EAQ90899.1 - 0.0043 16.9 9.0 0.018 15.0 0.0 6.1 9 0 0 9 9 9 1 PPR repeat Lyase_catalyt PF09093.6 EAQ90899.1 - 0.071 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Lyase, catalytic TPR_14 PF13428.1 EAQ90899.1 - 0.2 12.4 2.4 19 6.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP_bind_4 PF01902.12 EAQ90900.1 - 1.7e-11 43.9 0.0 1.5e-05 24.5 0.0 3.8 3 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EAQ90900.1 - 3.3e-09 36.5 0.1 5.7e-07 29.3 0.0 3.1 2 1 0 2 2 2 1 Endoribonuclease L-PSP Tctex-1 PF03645.8 EAQ90900.1 - 0.29 10.9 0.0 0.61 9.9 0.0 1.4 1 0 0 1 1 1 0 Tctex-1 family zf-C2H2 PF00096.21 EAQ90901.1 - 5.9e-10 38.8 11.6 7.6e-07 29.1 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ90901.1 - 1.3e-06 28.2 9.7 0.00098 19.2 4.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ90901.1 - 2.2e-06 27.6 3.1 2.2e-06 27.6 2.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EAQ90901.1 - 0.00018 21.5 2.6 0.051 13.8 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAQ90901.1 - 0.0039 17.0 0.3 0.0039 17.0 0.2 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger SOG2 PF10428.4 EAQ90901.1 - 0.58 8.7 12.9 0.024 13.3 4.5 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein Herpes_DNAp_acc PF04929.7 EAQ90901.1 - 2.9 6.7 6.7 4.7 6.0 4.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-C2HC_2 PF13913.1 EAQ90901.1 - 9.9 5.9 9.1 6.6 6.5 2.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF4187 PF13821.1 EAQ90905.1 - 8.3e-15 54.1 0.7 8.3e-15 54.1 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EAQ90905.1 - 0.00059 19.5 16.2 0.0014 18.4 2.8 2.5 2 0 0 2 2 2 2 G-patch domain COesterase PF00135.23 EAQ90906.1 - 5.9e-70 236.4 0.1 1.1e-69 235.6 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ90906.1 - 0.0032 17.0 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ90906.1 - 0.012 14.8 0.2 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-H2C2_2 PF13465.1 EAQ90907.1 - 5.3e-16 58.0 20.1 9.9e-09 35.0 1.4 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ90907.1 - 2.4e-10 40.0 24.0 0.0037 17.5 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ90907.1 - 7.3e-08 32.2 21.8 0.0074 16.5 4.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ90907.1 - 0.001 19.1 9.7 0.67 10.1 2.3 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 EAQ90907.1 - 0.014 15.2 5.1 1.1 9.1 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-RING_3 PF14369.1 EAQ90907.1 - 0.019 14.9 5.0 8.5 6.4 0.1 3.4 3 0 0 3 3 3 0 zinc-finger zf-Di19 PF05605.7 EAQ90907.1 - 0.02 15.0 12.5 0.093 12.8 5.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EAQ90907.1 - 0.023 14.6 10.8 0.79 9.7 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Sec2p PF06428.6 EAQ90907.1 - 0.027 14.3 0.6 0.047 13.5 0.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PyrI_C PF02748.10 EAQ90907.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.2 EAQ90907.1 - 0.16 11.8 7.9 5.5 6.8 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.6 EAQ90907.1 - 0.42 10.2 11.5 0.06 12.9 0.7 3.6 2 1 2 4 4 4 0 GAGA factor Zn-ribbon_8 PF09723.5 EAQ90907.1 - 0.62 10.0 10.6 9.3 6.3 2.7 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 EAQ90907.1 - 1.4 8.6 7.1 41 3.9 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EAQ90907.1 - 1.7 8.2 7.6 36 4.0 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EAQ90907.1 - 2.2 8.4 11.7 2.2 8.4 1.7 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.9 EAQ90907.1 - 2.7 7.5 6.9 1.7 8.1 0.7 2.6 2 1 0 2 2 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.7 EAQ90907.1 - 2.9 7.7 6.3 2 8.2 1.6 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-TFIIB PF13453.1 EAQ90907.1 - 5.5 6.2 5.9 9 5.5 1.7 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2225 PF09986.4 EAQ90907.1 - 5.5 6.3 9.2 15 4.9 3.5 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2HC_2 PF13913.1 EAQ90907.1 - 6 6.6 7.4 0.4 10.4 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type C1_4 PF07975.7 EAQ90907.1 - 7 6.7 7.9 40 4.3 5.1 2.3 1 1 0 1 1 1 0 TFIIH C1-like domain zf-BED PF02892.10 EAQ90907.1 - 9.8 6.0 10.4 2.2 8.1 3.8 2.2 1 1 1 2 2 2 0 BED zinc finger BNR PF02012.15 EAQ90908.1 - 7.4e-12 43.2 35.4 0.41 10.6 0.0 11.9 12 0 0 12 12 12 8 BNR/Asp-box repeat LAM_C PF12544.3 EAQ90911.1 - 3.6e-05 23.8 0.0 7.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 EAQ90911.1 - 0.0036 17.4 0.0 0.023 14.8 0.0 2.3 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 EAQ90911.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain SHS2_Rpb7-N PF03876.12 EAQ90912.1 - 3.8e-15 55.7 0.0 6.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EAQ90912.1 - 1.6e-08 34.4 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 EAQ90913.1 - 9.1e-14 51.1 0.5 1.2e-13 50.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) ATP_bind_1 PF03029.12 EAQ90915.1 - 3.7e-66 223.0 0.1 3.7e-65 219.8 0.1 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAQ90915.1 - 7.1e-05 23.6 0.1 0.00018 22.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ90915.1 - 0.00013 21.8 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAQ90915.1 - 0.00017 21.7 0.0 0.00035 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EAQ90915.1 - 0.00042 19.9 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ90915.1 - 0.0005 20.2 0.0 0.0029 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EAQ90915.1 - 0.0052 16.4 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EAQ90915.1 - 0.0062 15.9 0.0 0.014 14.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EAQ90915.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sec34 PF04136.10 EAQ90915.1 - 0.017 14.7 0.3 0.15 11.7 0.1 2.2 2 1 0 2 2 2 0 Sec34-like family AAA_18 PF13238.1 EAQ90915.1 - 0.02 15.2 0.2 0.093 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAQ90915.1 - 0.022 14.1 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.22 EAQ90915.1 - 0.025 14.0 0.1 3.1 7.1 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 EAQ90915.1 - 0.025 13.6 0.1 0.066 12.2 0.0 1.7 2 0 0 2 2 2 0 Septin ArsA_ATPase PF02374.10 EAQ90915.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase MMR_HSR1 PF01926.18 EAQ90915.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.1 EAQ90915.1 - 0.031 14.2 0.2 0.14 12.0 0.0 2.2 2 1 0 2 2 1 0 AAA domain SRP54 PF00448.17 EAQ90915.1 - 0.033 13.6 0.0 0.084 12.3 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EAQ90915.1 - 0.039 13.6 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EAQ90915.1 - 0.039 13.1 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ90915.1 - 0.046 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 EAQ90915.1 - 0.062 13.0 0.2 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 EAQ90915.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EAQ90915.1 - 0.062 12.7 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EAQ90915.1 - 0.064 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EAQ90915.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EAQ90915.1 - 0.073 12.7 0.1 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 NACHT domain PPV_E1_C PF00519.12 EAQ90915.1 - 0.084 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Hpr_kinase_C PF07475.7 EAQ90915.1 - 0.14 11.4 0.4 0.23 10.7 0.1 1.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain PHD PF00628.24 EAQ90916.1 - 7.8e-08 31.8 5.4 1.2e-07 31.2 3.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EAQ90916.1 - 0.041 13.2 2.8 0.068 12.4 1.9 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EAQ90916.1 - 2 8.2 5.0 0.62 9.8 1.5 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Iso_dh PF00180.15 EAQ90917.1 - 9.4e-107 356.9 0.0 9e-89 297.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.8 EAQ90917.1 - 0.3 10.5 2.0 0.52 9.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1762 PF08574.5 EAQ90920.1 - 1.1e-07 32.2 8.9 1.1e-07 32.2 6.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) DUF3681 PF12442.3 EAQ90922.1 - 0.045 13.9 0.1 0.055 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) His_Phos_1 PF00300.17 EAQ90923.1 - 3.1e-21 76.1 0.0 6e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ADP_PFK_GK PF04587.10 EAQ90924.1 - 0.18 10.0 0.3 0.25 9.4 0.2 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region RabGAP-TBC PF00566.13 EAQ90925.1 - 6.3e-08 32.3 0.0 8.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PBD PF00786.23 EAQ90927.1 - 0.011 16.1 1.2 0.029 14.8 0.1 2.4 2 0 0 2 2 2 0 P21-Rho-binding domain Histone PF00125.19 EAQ90928.1 - 5e-29 100.2 0.6 5.5e-29 100.1 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAQ90928.1 - 3e-05 24.1 0.0 3.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAQ90928.1 - 0.0072 16.3 0.1 0.0082 16.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EAQ90928.1 - 0.081 12.1 0.1 0.083 12.1 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T adh_short PF00106.20 EAQ90929.1 - 7.4e-17 61.7 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ90929.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ90929.1 - 4.1e-06 26.4 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ90929.1 - 0.0012 18.8 0.1 0.0035 17.3 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ90929.1 - 0.0033 16.1 0.1 0.0058 15.3 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EAQ90929.1 - 0.075 12.2 0.1 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 EAQ90929.1 - 0.09 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Bromodomain PF00439.20 EAQ90930.1 - 9e-25 86.4 0.1 1.8e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EAQ90930.1 - 2e-09 37.4 0.1 3.7e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ90930.1 - 4.9e-08 32.8 0.1 9.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPT PF03151.11 EAQ90931.1 - 1.7e-10 40.7 5.6 1.7e-10 40.7 3.9 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EAQ90931.1 - 7.1e-10 38.2 14.6 8.9e-10 37.9 10.1 1.1 1 0 0 1 1 1 1 UAA transporter family PHO4 PF01384.15 EAQ90931.1 - 0.0032 16.1 2.8 0.0032 16.1 1.9 2.3 2 1 0 2 2 2 1 Phosphate transporter family EamA PF00892.15 EAQ90931.1 - 0.21 11.6 21.8 0.075 13.0 3.8 2.5 2 1 0 2 2 2 0 EamA-like transporter family Abi PF02517.11 EAQ90932.1 - 1e-13 51.2 4.9 1e-13 51.2 3.4 2.8 2 1 0 2 2 2 1 CAAX protease self-immunity MBOAT PF03062.14 EAQ90934.1 - 8.4e-53 179.5 2.1 8.4e-53 179.5 1.4 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF2404 PF10296.4 EAQ90936.1 - 1.1e-07 31.8 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Sec1 PF00995.18 EAQ90937.1 - 3e-150 501.5 0.0 3.4e-150 501.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GSH_synth_ATP PF03917.12 EAQ90938.1 - 6.5e-54 182.9 0.0 2.2e-52 177.8 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EAQ90938.1 - 2.9e-29 101.2 0.0 5.5e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EAQ90939.1 - 6.7e-35 120.3 0.1 6.5e-31 107.2 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ90939.1 - 2.9e-13 49.4 0.5 6.9e-13 48.2 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ90939.1 - 0.00026 20.8 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EAQ90939.1 - 0.028 13.2 0.0 0.064 12.0 0.0 1.5 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Aminotran_1_2 PF00155.16 EAQ90940.1 - 4.6e-26 91.6 0.3 3.2e-23 82.2 0.0 3.2 2 1 2 4 4 4 2 Aminotransferase class I and II Aminotran_5 PF00266.14 EAQ90940.1 - 0.00021 20.1 0.0 0.00033 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Preseq_ALAS PF09029.5 EAQ90940.1 - 0.065 13.2 0.4 0.17 11.9 0.3 1.8 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence DUF3405 PF11885.3 EAQ90940.1 - 0.085 11.0 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Zn_clus PF00172.13 EAQ90941.1 - 0.011 15.6 13.1 0.018 14.9 9.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_11 PF13086.1 EAQ90943.1 - 5.2e-06 26.2 0.0 0.003 17.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.1 EAQ90943.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAQ90943.1 - 0.07 13.2 0.3 0.64 10.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_12 PF13087.1 EAQ90943.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Lyase_1 PF00206.15 EAQ90944.1 - 1.2e-16 60.7 0.1 4.6e-16 58.8 0.1 1.8 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 EAQ90944.1 - 7.5e-12 45.0 0.0 2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus AF0941-like PF14591.1 EAQ90944.1 - 0.0091 16.0 2.5 12 5.9 0.1 3.8 2 2 2 4 4 4 2 AF0941-like TraH PF06122.6 EAQ90944.1 - 0.039 12.7 0.1 0.062 12.0 0.1 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Glyco_hydro_30 PF02055.11 EAQ90945.1 - 1.7e-19 69.3 0.6 1.3e-13 50.0 0.2 2.5 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EAQ90945.1 - 4.4e-12 45.6 3.2 7.5e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 HK PF02110.10 EAQ90946.1 - 5e-58 196.1 5.9 7.5e-30 103.8 0.1 2.8 2 1 1 3 3 3 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EAQ90946.1 - 1.1e-56 190.7 2.3 1.8e-56 190.1 1.6 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EAQ90946.1 - 2.4e-05 23.7 0.1 5.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Isochorismatase PF00857.15 EAQ90947.1 - 8.1e-26 90.9 0.0 1.2e-25 90.3 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 EAQ90949.1 - 2e-20 73.6 0.0 2.6e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ90949.1 - 9.3e-18 64.9 0.0 1.1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EAQ90949.1 - 0.002 17.8 0.1 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family LysM PF01476.15 EAQ90950.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 LysM domain CPSF_A PF03178.10 EAQ90951.1 - 1.5e-100 336.4 0.0 7.5e-100 334.1 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EAQ90951.1 - 8.5e-62 208.9 0.0 1.6e-61 208.0 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EAQ90951.1 - 0.13 12.1 0.1 0.55 10.2 0.1 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-Mss51 PF13824.1 EAQ90952.1 - 2.1e-26 91.5 7.4 4.5e-26 90.4 5.1 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EAQ90952.1 - 0.024 14.5 2.5 0.024 14.5 1.7 2.0 2 0 0 2 2 2 0 MYND finger PXA PF02194.10 EAQ90953.1 - 3.9e-43 147.1 0.2 9.5e-43 145.9 0.2 1.6 2 0 0 2 2 2 1 PXA domain Herpes_UL45 PF05473.7 EAQ90953.1 - 0.13 11.7 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UL45 protein DUF3123 PF11321.3 EAQ90954.1 - 0.24 11.6 2.5 0.57 10.4 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) HTH_Tnp_Tc5 PF03221.11 EAQ90955.1 - 1e-10 41.2 0.0 2.7e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EAQ90955.1 - 4.4e-07 29.2 0.0 8e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MAP65_ASE1 PF03999.7 EAQ90955.1 - 0.0047 15.5 1.7 0.0089 14.6 1.2 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MarR PF01047.17 EAQ90955.1 - 0.014 15.0 1.4 0.04 13.6 0.0 2.4 3 0 0 3 3 3 0 MarR family HTH_Tnp_4 PF13613.1 EAQ90955.1 - 0.016 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 EAQ90955.1 - 0.072 12.7 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 EAQ90955.1 - 0.076 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TGS PF02824.16 EAQ90958.1 - 3.5e-18 65.1 0.0 7e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EAQ90958.1 - 8.3e-18 64.4 0.0 2.3e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ90958.1 - 4.7e-09 35.7 0.0 2.2e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EAQ90958.1 - 4.3e-05 23.0 0.1 0.49 9.7 0.0 3.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAQ90958.1 - 0.00023 21.0 0.1 0.045 13.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EAQ90958.1 - 0.0041 15.9 0.2 0.016 13.9 0.1 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EAQ90958.1 - 0.022 15.2 0.0 0.31 11.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Arf PF00025.16 EAQ90958.1 - 0.056 12.6 0.1 7 5.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF211 PF02680.9 EAQ90958.1 - 0.068 12.9 0.1 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Ank_2 PF12796.2 EAQ90960.1 - 5e-28 97.2 0.1 2.3e-18 66.3 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ90960.1 - 2.4e-20 71.2 4.9 7.1e-08 31.8 0.2 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EAQ90960.1 - 4.6e-18 64.8 2.6 7.9e-09 35.4 0.2 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ90960.1 - 9.1e-18 64.2 0.5 1.7e-05 25.1 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ90960.1 - 9.8e-16 56.2 0.1 5.7e-05 22.9 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Steroid_dh PF02544.11 EAQ90961.1 - 6.1e-13 48.7 0.9 1.1e-12 47.8 0.6 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ATP-synt_DE_N PF02823.11 EAQ90962.1 - 5.4e-19 67.7 0.1 7.9e-19 67.2 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF1537 PF07005.6 EAQ90962.1 - 0.0043 16.7 0.9 0.0074 15.9 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function, DUF1537 DUF2457 PF10446.4 EAQ90963.1 - 4.9e-177 589.2 48.6 4.9e-177 589.2 33.7 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 EAQ90963.1 - 0.046 11.6 33.2 0.11 10.4 23.0 1.6 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 EAQ90963.1 - 0.99 8.8 6.7 2.3 7.5 4.6 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Arf PF00025.16 EAQ90964.1 - 1.7e-65 219.4 0.0 2.1e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAQ90964.1 - 2.7e-10 39.5 0.1 1.1e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EAQ90964.1 - 2e-08 34.7 0.0 2.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAQ90964.1 - 1.6e-07 30.8 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EAQ90964.1 - 2e-07 30.4 0.0 2.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAQ90964.1 - 2.8e-07 30.4 0.0 3.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EAQ90964.1 - 1e-05 24.8 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAQ90964.1 - 0.00012 21.6 0.1 0.0051 16.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.3 EAQ90964.1 - 0.11 11.7 0.0 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 EAQ90964.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3336 PF11815.3 EAQ90965.1 - 5.7e-55 184.8 1.8 8.6e-55 184.2 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EAQ90965.1 - 3.5e-20 72.7 0.3 1.4e-19 70.8 0.0 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase GRA6 PF05084.8 EAQ90966.1 - 3.8 6.9 6.0 6.2 6.2 4.2 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) SOG2 PF10428.4 EAQ90966.1 - 8.3 4.9 9.4 10 4.6 6.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Polysacc_deac_1 PF01522.16 EAQ90968.1 - 2.4e-29 101.4 0.0 4.1e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EAQ90968.1 - 4.5e-07 29.7 41.4 7.8e-06 25.7 10.0 4.2 4 0 0 4 4 4 2 Chitin recognition protein DUF2332 PF10094.4 EAQ90969.1 - 0.085 11.8 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) Aldedh PF00171.17 EAQ90971.1 - 1.9e-184 613.3 0.2 2.2e-184 613.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EAQ90971.1 - 0.00023 20.4 0.1 0.0081 15.4 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1487) LMBR1 PF04791.11 EAQ90972.1 - 2.3e-28 99.0 4.3 3.2e-28 98.5 3.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PgaD PF13994.1 EAQ90972.1 - 1.4 8.4 8.1 0.42 10.0 1.0 3.1 2 0 0 2 2 2 0 PgaD-like protein SGL PF08450.7 EAQ90974.1 - 7e-64 215.5 0.0 9.5e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 EAQ90974.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 EAQ90974.1 - 0.16 12.0 0.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Two component regulator propeller bZIP_2 PF07716.10 EAQ90977.1 - 3.1e-05 23.7 23.9 3.1e-05 23.7 16.6 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EAQ90977.1 - 9.7e-05 22.2 21.7 0.00084 19.2 14.3 2.2 1 1 1 2 2 2 2 bZIP transcription factor HCR PF07111.7 EAQ90977.1 - 0.035 12.1 8.2 0.05 11.6 5.7 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) HlyD PF00529.15 EAQ90977.1 - 0.14 11.4 6.3 0.23 10.7 4.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein CENP-H PF05837.7 EAQ90977.1 - 0.17 12.0 5.7 0.28 11.3 3.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4140 PF13600.1 EAQ90977.1 - 0.34 11.3 6.5 0.83 10.1 4.5 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EAQ90977.1 - 0.46 9.4 9.9 0.66 8.9 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EAQ90977.1 - 1 7.1 7.0 1.4 6.6 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EAQ90977.1 - 5.1 6.6 13.2 7.8 6.0 9.1 1.2 1 0 0 1 1 1 0 IncA protein Coiled PF05710.7 EAQ90979.1 - 0.039 14.4 6.6 0.052 14.0 4.4 1.3 1 1 0 1 1 1 0 Coiled coil SIN1 PF05422.7 EAQ90980.1 - 7.3e-41 140.2 2.3 3.7e-19 68.6 0.0 3.2 3 0 0 3 3 3 3 Stress-activated map kinase interacting protein 1 (SIN1) PRCC PF10253.4 EAQ90981.1 - 2e-30 106.8 8.2 2e-30 106.8 5.7 2.9 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting TPR_11 PF13414.1 EAQ90981.1 - 1.6e-21 75.7 18.5 3.8e-08 32.8 0.9 5.5 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EAQ90981.1 - 6.6e-19 66.6 14.3 0.00044 19.7 0.0 7.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ90981.1 - 3.1e-14 51.6 29.8 0.052 13.4 0.1 8.8 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ90981.1 - 3.8e-12 45.0 7.4 0.019 14.7 0.0 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat APC8 PF04049.8 EAQ90981.1 - 3.6e-11 42.9 0.7 9.2e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.1 EAQ90981.1 - 7.9e-11 41.5 28.1 0.034 14.7 0.3 8.9 6 1 3 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ90981.1 - 3.3e-08 33.3 25.5 0.0013 18.6 1.6 5.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ90981.1 - 4.7e-07 30.3 34.2 2e-05 25.1 0.6 6.7 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ90981.1 - 1.1e-06 27.9 10.5 1.6 8.7 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ90981.1 - 2e-06 27.5 7.4 20 5.6 0.1 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ90981.1 - 0.031 14.1 17.7 0.077 12.8 0.3 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ90981.1 - 0.055 13.8 20.7 0.25 11.6 0.4 5.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ90981.1 - 2.1 8.9 21.2 1 9.9 0.1 7.1 6 1 0 6 6 6 0 Tetratricopeptide repeat UCH PF00443.24 EAQ90984.1 - 5.2e-38 130.7 0.7 8.9e-38 129.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EAQ90984.1 - 2.2e-16 59.3 0.0 3.1e-07 29.2 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EAQ90984.1 - 3.4e-12 46.4 1.2 1.4e-09 37.8 0.8 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.6 EAQ90985.1 - 6.2e-09 35.8 0.0 1.6e-08 34.5 0.0 1.7 2 1 0 2 2 2 1 RNase P subunit Pop3 Pyr_redox_2 PF07992.9 EAQ90986.1 - 8.8e-32 110.6 0.0 1.4e-31 109.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ90986.1 - 1.3e-08 35.0 0.0 4.4e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ90986.1 - 0.019 15.0 0.0 0.095 12.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Anillin PF08174.6 EAQ90987.1 - 2.7e-33 114.9 0.1 1.2e-32 112.8 0.0 2.3 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 EAQ90987.1 - 7.7e-07 29.2 0.0 2.3e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF697 PF05128.7 EAQ90987.1 - 0.091 12.2 0.6 0.15 11.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF697) His_biosynth PF00977.16 EAQ90988.1 - 3e-33 114.9 0.0 3.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EAQ90988.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EAQ90989.1 - 0.001 19.1 4.6 0.001 19.1 3.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) Nop14 PF04147.7 EAQ90989.1 - 0.11 10.3 13.0 0.15 9.9 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAQ90989.1 - 1.6 6.7 7.5 2.4 6.0 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein STE PF02200.11 EAQ90990.1 - 1.4e-61 205.4 0.6 2.5e-61 204.6 0.2 1.5 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EAQ90990.1 - 0.00025 21.1 3.8 0.00082 19.5 2.7 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ90990.1 - 0.00069 19.7 2.3 0.0017 18.5 1.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger NOC3p PF07540.6 EAQ90992.1 - 5.5e-30 103.4 2.2 6.8e-30 103.1 0.0 2.4 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 EAQ90992.1 - 1e-29 103.0 0.0 3.7e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 CBF/Mak21 family BP28CT PF08146.7 EAQ90993.1 - 9.3e-46 155.3 0.0 3.1e-45 153.6 0.0 2.0 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EAQ90993.1 - 6.8e-25 87.3 0.5 6.8e-25 87.3 0.4 6.2 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EAQ90993.1 - 0.00049 19.9 7.5 0.013 15.5 0.1 5.6 5 0 0 5 5 5 1 HEAT repeat MAP7 PF05672.6 EAQ90994.1 - 0.53 9.6 39.8 1.2 8.5 27.6 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF1682 PF07946.9 EAQ90994.1 - 1.5 7.5 17.8 2.7 6.7 12.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Selenoprotein_S PF06936.6 EAQ90994.1 - 2.4 7.6 12.4 5.1 6.5 8.6 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) SAPS PF04499.10 EAQ90994.1 - 2.4 6.6 6.1 3.6 6.0 4.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 EAQ90994.1 - 8.2 3.9 5.8 11 3.5 4.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PHF5 PF03660.9 EAQ90995.1 - 2.1e-51 172.4 10.6 2.4e-51 172.3 7.4 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EAQ90995.1 - 0.83 9.5 15.5 0.16 11.7 5.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EAQ90995.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EAQ90995.1 - 5.9 6.6 15.2 0.2 11.3 4.4 2.5 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 EAQ90996.1 - 1.2e-07 31.4 17.4 1.2e-07 31.4 12.0 2.7 1 1 2 3 3 3 2 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 EAQ90997.1 - 2.3e-32 112.6 1.0 3e-32 112.3 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ90997.1 - 1.2e-17 64.2 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ90997.1 - 3.6e-13 49.4 0.0 1.4e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ90997.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S28 PF05577.7 EAQ90997.1 - 0.027 13.0 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.5 EAQ90997.1 - 0.033 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Chlorophyllase PF07224.6 EAQ90997.1 - 0.051 12.3 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Cript PF10235.4 EAQ90998.1 - 5.6e-30 103.5 9.9 8.6e-30 102.9 6.9 1.2 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT Churchill PF06573.6 EAQ90998.1 - 0.005 16.8 0.8 0.0062 16.5 0.1 1.5 2 0 0 2 2 2 1 Churchill protein DZR PF12773.2 EAQ90998.1 - 0.011 15.5 12.4 0.051 13.4 6.0 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EAQ90998.1 - 0.043 13.0 9.2 0.58 9.4 1.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_5 PF14634.1 EAQ90998.1 - 0.052 13.2 3.8 0.052 13.2 2.6 2.7 3 0 0 3 3 3 0 zinc-RING finger domain LIM PF00412.17 EAQ90998.1 - 0.69 10.0 9.1 2 8.5 3.8 2.4 2 1 1 3 3 3 0 LIM domain OrfB_Zn_ribbon PF07282.6 EAQ90998.1 - 1 9.0 8.2 6.9 6.4 1.2 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.4 EAQ90998.1 - 2 7.5 7.4 3.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Mu-like prophage protein Com Ribosomal_L32p PF01783.18 EAQ90998.1 - 3.2 7.9 11.4 0.35 11.0 1.4 2.9 2 1 1 3 3 3 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.1 EAQ90998.1 - 4.7 6.8 14.6 0.97 9.0 2.1 3.1 2 1 2 4 4 4 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EAQ90998.1 - 5.1 7.2 10.6 2.6 8.1 4.7 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ90998.1 - 5.2 6.8 12.0 13 5.5 5.6 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) E1-E2_ATPase PF00122.15 EAQ90999.1 - 5.3e-22 77.9 0.1 9.7e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EAQ90999.1 - 1.8e-20 73.9 0.1 4.3e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ90999.1 - 4.2e-18 66.5 0.6 4.4e-17 63.2 0.4 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ90999.1 - 7.1e-12 45.1 0.0 2.2e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAQ90999.1 - 0.00058 19.5 0.4 0.0034 16.9 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ90999.1 - 0.015 15.5 0.1 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Gp_dh_N PF00044.19 EAQ90999.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ecl1 PF12855.2 EAQ91000.1 - 1.1e-08 34.2 1.4 2.1e-08 33.3 1.0 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Kelch_5 PF13854.1 EAQ91001.1 - 1.9e-12 46.8 16.2 5.6e-12 45.3 0.4 5.4 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 EAQ91001.1 - 0.00066 19.7 19.1 0.8 9.9 0.3 6.1 5 1 1 6 6 6 3 Kelch motif Lamp PF01299.12 EAQ91001.1 - 0.022 13.9 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) EphA2_TM PF14575.1 EAQ91001.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EAQ91001.1 - 0.18 10.0 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_2 PF07646.10 EAQ91001.1 - 0.21 11.3 16.3 0.9 9.4 0.0 5.1 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.20 EAQ91001.1 - 0.95 9.0 14.7 4.3 6.9 0.0 5.4 6 0 0 6 6 6 0 Kelch motif MFS_1 PF07690.11 EAQ91002.1 - 1.6e-17 63.2 50.0 1.2e-10 40.6 10.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily SNN_linker PF09050.5 EAQ91002.1 - 0.96 9.0 3.5 2.1 7.9 2.4 1.5 1 0 0 1 1 1 0 Stannin unstructured linker Zn_clus PF00172.13 EAQ91003.1 - 0.012 15.5 6.3 0.024 14.5 4.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WAC_Acf1_DNA_bd PF10537.4 EAQ91004.1 - 2.1e-38 130.5 0.0 8.1e-38 128.7 0.0 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EAQ91004.1 - 1.2e-16 60.2 0.5 2e-16 59.4 0.4 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EAQ91004.1 - 1.1e-13 50.4 0.5 2.1e-13 49.5 0.3 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EAQ91004.1 - 0.00072 19.3 0.1 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 EAQ91004.1 - 0.00098 18.8 0.1 0.0027 17.4 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Nop53 PF07767.6 EAQ91004.1 - 1.1 8.2 35.1 1.2 8.1 1.7 3.4 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) Alg6_Alg8 PF03155.10 EAQ91005.1 - 1e-125 420.2 28.5 6.3e-98 328.6 11.3 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 EAQ91006.1 - 5.7e-29 100.8 0.0 1.2e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.7 EAQ91006.1 - 0.0021 17.9 0.0 0.1 12.4 0.0 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Leu_zip PF15294.1 EAQ91006.1 - 0.015 14.4 0.3 0.021 13.9 0.2 1.2 1 0 0 1 1 1 0 Leucine zipper DUF3708 PF12501.3 EAQ91006.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Peptidase_M24 PF00557.19 EAQ91007.1 - 8.6e-72 241.0 0.0 1.9e-71 239.9 0.0 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EAQ91007.1 - 2.2e-25 88.6 0.1 1.6e-23 82.6 0.0 2.7 3 0 0 3 3 3 2 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.13 EAQ91008.1 - 6.7e-33 113.6 0.2 1.2e-32 112.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.17 EAQ91008.1 - 0.83 8.6 2.8 1.4 7.8 1.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_POL_M_15KD PF02150.11 EAQ91008.1 - 2.2 8.0 4.8 0.44 10.2 0.6 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit RPN7 PF10602.4 EAQ91011.1 - 7.3e-50 168.7 0.1 1.6e-49 167.6 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EAQ91011.1 - 1.2e-15 57.6 0.1 7.6e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain COG2 PF06148.6 EAQ91011.1 - 0.017 15.0 0.1 0.076 12.8 0.0 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HrpB1_HrpK PF09613.5 EAQ91011.1 - 0.046 13.2 0.1 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2200 PF09966.4 EAQ91011.1 - 0.049 13.5 0.1 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) Prp18 PF02840.10 EAQ91012.1 - 4.5e-51 172.5 0.0 8.9e-51 171.5 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 EAQ91012.1 - 4.5e-12 45.0 1.0 4.5e-12 45.0 0.7 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 EAQ91012.1 - 0.0013 18.1 25.5 0.0022 17.3 17.7 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 EAQ91012.1 - 0.024 13.8 13.8 0.037 13.2 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mucin PF01456.12 EAQ91012.1 - 0.24 11.1 8.1 0.43 10.3 5.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein TT_ORF1 PF02956.9 EAQ91012.1 - 4.1 5.7 7.7 5.8 5.2 5.3 1.3 1 0 0 1 1 1 0 TT viral orf 1 Dicty_REP PF05086.7 EAQ91012.1 - 5.6 4.5 8.8 7.3 4.2 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAP18 PF06487.7 EAQ91013.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NDUF_B4 PF07225.7 EAQ91014.1 - 0.0064 16.2 0.1 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N_2 PF13409.1 EAQ91015.1 - 3.8e-07 30.0 0.0 2.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ91015.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAQ91015.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAQ91015.1 - 0.0002 21.2 0.0 0.00055 19.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ91015.1 - 0.006 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ91015.1 - 0.033 14.6 0.0 0.066 13.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 EAQ91016.1 - 4.8e-07 29.9 0.9 1.6e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 EAQ91016.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EAQ91016.1 - 0.057 12.7 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Synaptobrevin PF00957.16 EAQ91017.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.5 3 0 0 3 3 3 0 Synaptobrevin MIF PF01187.13 EAQ91018.1 - 2.9e-07 30.5 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.7 EAQ91019.1 - 1.6e-71 240.1 0.1 1.9e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAQ91019.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ91019.1 - 0.0091 15.2 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AIG2_2 PF13772.1 EAQ91020.1 - 0.0031 17.5 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family Amidoligase_2 PF12224.3 EAQ91021.1 - 4.2e-09 36.3 0.0 5.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme AIG2 PF06094.7 EAQ91022.1 - 9.8e-10 38.8 0.1 2.7e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 EAQ91022.1 - 0.0001 22.3 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 AIG2-like family DUF2428 PF10350.4 EAQ91025.1 - 3.1e-69 232.8 0.1 1.5e-68 230.5 0.0 2.1 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EAQ91025.1 - 1.7e-08 33.8 13.8 2.8 8.2 0.1 8.5 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EAQ91025.1 - 4.2e-05 23.7 6.6 0.024 14.8 0.1 5.2 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EAQ91025.1 - 4.2 7.9 18.0 1.7 9.2 0.9 6.4 5 1 1 6 6 6 0 HEAT-like repeat Tim17 PF02466.14 EAQ91026.1 - 4.4e-27 94.6 3.7 6e-27 94.2 2.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CoaE PF01121.15 EAQ91029.1 - 1.6e-42 144.9 0.0 2e-41 141.3 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EAQ91029.1 - 0.00055 20.7 2.2 0.0024 18.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EAQ91029.1 - 0.0038 17.1 0.0 0.03 14.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAQ91029.1 - 0.016 15.5 1.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EAQ91029.1 - 0.071 12.9 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase CcmH PF03918.9 EAQ91029.1 - 0.082 11.9 0.3 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein p450 PF00067.17 EAQ91031.1 - 9.7e-42 143.0 0.0 3.5e-38 131.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF1749 PF08538.5 EAQ91032.1 - 1.5e-85 286.7 0.0 1.8e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EAQ91032.1 - 8.5e-14 51.9 0.6 1.1e-13 51.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ91032.1 - 2.3e-05 24.1 0.1 4.4e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 EAQ91033.1 - 4.7e-37 127.5 0.0 7.6e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91033.1 - 5.5e-26 91.1 0.0 7.9e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ91033.1 - 0.00041 20.1 0.3 0.62 9.7 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EAQ91033.1 - 0.0098 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAQ91033.1 - 0.063 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Terminase_1 PF03354.10 EAQ91034.1 - 0.29 9.5 0.0 0.46 8.8 0.0 1.2 1 0 0 1 1 1 0 Phage Terminase SYF2 PF08231.7 EAQ91035.1 - 2.8e-05 24.2 0.4 2.8e-05 24.2 0.3 1.8 2 0 0 2 2 2 1 SYF2 splicing factor DUF1176 PF06674.6 EAQ91035.1 - 0.15 11.1 5.5 0.19 10.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) NAD_binding_10 PF13460.1 EAQ91036.1 - 2.1e-18 66.9 0.0 7.6e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 EAQ91036.1 - 1.5e-07 31.1 0.0 3.7e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ91036.1 - 2.9e-05 22.9 0.0 6.8e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAQ91036.1 - 0.00082 18.3 0.0 0.035 13.0 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EAQ91036.1 - 0.0017 18.2 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAQ91036.1 - 0.011 14.6 0.0 0.073 11.9 0.0 2.1 2 1 1 3 3 3 0 RmlD substrate binding domain NmrA PF05368.8 EAQ91036.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family YEATS PF03366.11 EAQ91037.1 - 3.8e-29 100.2 0.3 5.8e-29 99.6 0.2 1.3 1 0 0 1 1 1 1 YEATS family DUF2404 PF10296.4 EAQ91038.1 - 0.00029 20.9 0.0 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 EAQ91039.1 - 6.8e-30 104.1 0.0 6e-18 64.9 0.0 2.0 1 1 1 2 2 2 2 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.13 EAQ91040.1 - 4.8e-39 134.3 7.0 1e-29 103.6 0.0 2.7 3 0 0 3 3 3 2 Nucleoside transporter MFS_1 PF07690.11 EAQ91040.1 - 3.1e-06 26.1 44.5 0.00039 19.2 5.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2975 PF11188.3 EAQ91040.1 - 1.7 8.3 17.6 0.035 13.8 1.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) Catalase PF00199.14 EAQ91041.1 - 8.1e-144 479.0 1.5 2.6e-143 477.3 1.1 1.7 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EAQ91041.1 - 3.1e-21 74.9 0.0 5.6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF1682 PF07946.9 EAQ91043.1 - 1.6e-92 309.8 0.8 2e-92 309.5 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF77 PF01910.12 EAQ91044.1 - 2.6e-34 116.7 0.8 2.9e-34 116.5 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 EAQ91044.1 - 0.042 13.4 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF1180 PF06679.7 EAQ91045.1 - 0.14 12.0 1.5 0.3 10.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF605 PF04652.11 EAQ91045.1 - 9.7 5.4 12.7 14 4.9 8.8 1.1 1 0 0 1 1 1 0 Vta1 like Arf PF00025.16 EAQ91046.1 - 6.2e-21 74.4 0.1 4.4e-11 42.3 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ91046.1 - 0.00017 21.1 0.0 0.0005 19.5 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EAQ91046.1 - 0.0037 16.0 0.0 0.13 10.8 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EAQ91046.1 - 0.14 11.3 0.0 12 5.0 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RNase_PH PF01138.16 EAQ91047.1 - 2.6e-21 76.3 0.0 3.7e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAQ91047.1 - 7.4e-06 25.8 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EAQ91048.1 - 1.4e-87 293.4 11.8 1.6e-87 293.3 8.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TGF_beta_GS PF08515.7 EAQ91048.1 - 0.072 12.4 1.5 0.2 11.0 1.0 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif TFIIA PF03153.8 EAQ91048.1 - 0.23 11.3 13.5 0.34 10.7 9.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PLC-beta_C PF08703.5 EAQ91048.1 - 0.28 10.8 8.9 0.49 10.0 6.2 1.3 1 0 0 1 1 1 0 PLC-beta C terminal Nop14 PF04147.7 EAQ91048.1 - 0.71 7.7 22.4 0.84 7.4 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family EBP PF05241.7 EAQ91049.1 - 1.5e-61 206.7 6.6 1.8e-61 206.5 4.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein Nol1_Nop2_Fmu PF01189.12 EAQ91050.1 - 5.2e-15 55.5 0.0 1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family DUF29 PF01724.11 EAQ91050.1 - 0.021 14.6 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF1996 PF09362.5 EAQ91051.1 - 8.9e-61 205.5 0.0 1.3e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EAQ91051.1 - 9.5e-20 70.3 8.6 9.5e-20 70.3 6.0 2.3 2 0 0 2 2 2 1 WSC domain TPR_11 PF13414.1 EAQ91053.1 - 1.7e-24 85.2 12.9 1.2e-06 28.0 0.0 6.8 7 0 0 7 7 7 5 TPR repeat TPR_16 PF13432.1 EAQ91053.1 - 1.4e-10 41.5 24.3 0.002 18.7 0.0 8.1 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ91053.1 - 2.9e-10 39.9 18.6 0.011 15.6 0.0 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ91053.1 - 4.8e-10 38.4 7.1 0.18 11.6 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ91053.1 - 1.4e-09 37.1 14.8 0.069 12.7 0.0 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91053.1 - 4.3e-09 35.5 21.3 0.43 10.6 0.0 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ91053.1 - 5.4e-08 33.0 7.8 0.16 12.3 0.1 5.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ91053.1 - 4.2e-07 30.0 19.4 0.19 12.4 0.0 9.8 8 3 3 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ91053.1 - 1.5e-06 27.5 9.0 0.66 9.9 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EAQ91053.1 - 7e-06 26.0 2.4 0.039 14.0 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ91053.1 - 8.7e-05 22.4 0.8 85 3.7 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF236 PF03057.9 EAQ91053.1 - 0.21 11.5 2.0 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function TPR_6 PF13174.1 EAQ91053.1 - 0.47 11.0 14.3 5.1 7.7 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat SAM_2 PF07647.12 EAQ91054.1 - 1.1e-10 41.1 0.2 2e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAQ91054.1 - 4.8e-06 26.6 0.3 9.6e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EAQ91054.1 - 0.04 13.8 0.2 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif Ribosomal_L29e PF01779.12 EAQ91055.1 - 1.4e-23 82.4 9.3 2.5e-23 81.6 6.4 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.22 EAQ91056.1 - 6.9e-49 163.5 1.1 2.1e-17 62.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 EAQ91057.1 - 2.3e-25 89.2 0.0 3.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EAQ91057.1 - 6.9e-06 25.7 0.2 6.1e-05 22.6 0.0 2.5 3 0 0 3 3 3 1 Calpain large subunit, domain III ADH_N PF08240.7 EAQ91060.1 - 1.1e-30 105.6 1.8 1.5e-30 105.1 1.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EAQ91060.1 - 2.4e-06 27.0 0.2 6.1e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Sen15 PF09631.5 EAQ91061.1 - 5.4e-24 84.3 0.0 9.9e-24 83.4 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein Pkinase PF00069.20 EAQ91062.1 - 0.00076 18.7 0.0 0.0043 16.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DIM1 PF02966.11 EAQ91063.1 - 1.3e-69 231.8 0.0 1.4e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EAQ91063.1 - 0.094 12.8 0.1 0.15 12.1 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF2985 PF11204.3 EAQ91064.1 - 3.1e-37 126.1 1.1 5.7e-37 125.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.10 EAQ91065.1 - 1.6e-08 34.0 0.6 6.8e-08 31.9 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EAQ91065.1 - 8.9e-06 25.7 24.4 7.4e-05 22.7 1.9 3.4 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EAQ91065.1 - 0.00033 19.6 7.1 0.00063 18.7 4.9 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EAQ91065.1 - 0.055 13.1 0.3 0.055 13.1 0.2 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family Yippee-Mis18 PF03226.9 EAQ91066.1 - 1.4e-22 79.5 0.3 1.6e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ferric_reduct PF01794.14 EAQ91067.1 - 1.9e-20 73.2 12.6 3.8e-20 72.2 7.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EAQ91067.1 - 1e-18 67.7 0.0 5.7e-16 58.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAQ91067.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Nop14 PF04147.7 EAQ91069.1 - 1 7.1 2.5 1.5 6.6 1.7 1.1 1 0 0 1 1 1 0 Nop14-like family CLU PF13236.1 EAQ91070.1 - 5.4e-58 196.0 0.0 6.7e-38 130.3 0.0 2.5 1 1 1 2 2 2 2 Clustered mitochondria eIF3_p135 PF12807.2 EAQ91070.1 - 4.6e-52 176.3 1.5 8.9e-52 175.4 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EAQ91070.1 - 1.6e-32 111.2 17.9 3.6e-12 46.0 0.1 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 EAQ91070.1 - 1.5e-23 82.7 0.3 3.4e-23 81.5 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EAQ91070.1 - 7.5e-18 63.8 4.4 0.00024 20.9 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ91070.1 - 6.9e-06 25.6 8.6 0.16 11.6 0.8 3.5 1 1 1 3 3 3 3 TPR repeat DUF727 PF05303.7 EAQ91070.1 - 0.00068 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.1 EAQ91070.1 - 0.027 14.2 3.1 0.42 10.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91070.1 - 0.27 11.2 12.8 1 9.4 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DDHD PF02862.12 EAQ91070.1 - 0.96 9.1 8.3 0.16 11.7 2.9 1.8 2 0 0 2 2 2 0 DDHD domain Fork_head PF00250.13 EAQ91071.1 - 4.3e-33 113.2 0.1 8.2e-33 112.3 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EAQ91071.1 - 0.00032 20.7 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Aminotran_3 PF00202.16 EAQ91072.1 - 1.9e-71 240.6 0.0 3.1e-71 239.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III AhpC-TSA_2 PF13911.1 EAQ91073.1 - 7.6e-08 32.2 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Fungal_trans_2 PF11951.3 EAQ91073.1 - 1.5e-06 27.0 0.1 2.1e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.24 EAQ91075.1 - 1.8e-98 325.8 0.0 9.6e-48 161.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EAQ91075.1 - 1.9e-19 69.3 1.2 5.4e-19 67.9 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EAQ91075.1 - 1e-13 50.9 0.0 6.7e-06 25.3 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EAQ91075.1 - 1.1e-13 51.4 0.0 2.6e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAQ91075.1 - 5e-13 48.9 0.4 9.4e-07 28.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EAQ91075.1 - 1.5e-12 47.6 0.0 1.3e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAQ91075.1 - 3.9e-12 46.4 0.4 0.00069 19.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ91075.1 - 1.2e-11 44.9 0.0 0.00038 20.5 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EAQ91075.1 - 2.5e-11 44.4 0.0 0.00021 22.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EAQ91075.1 - 2.6e-09 36.2 0.0 0.00093 18.0 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EAQ91075.1 - 1.4e-08 34.3 5.5 0.017 14.4 0.0 4.6 2 2 2 4 4 4 3 AAA domain AAA_14 PF13173.1 EAQ91075.1 - 1.9e-08 34.2 0.0 0.0012 18.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EAQ91075.1 - 3e-08 33.2 0.0 0.0053 16.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EAQ91075.1 - 3.1e-08 33.2 1.6 0.0083 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Zeta_toxin PF06414.7 EAQ91075.1 - 1.3e-07 30.9 0.1 0.008 15.2 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EAQ91075.1 - 1.6e-07 30.6 0.2 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EAQ91075.1 - 3.9e-07 29.6 0.0 9.8e-07 28.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 EAQ91075.1 - 4.7e-07 29.9 0.0 0.026 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 EAQ91075.1 - 9e-07 28.2 0.7 0.23 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 EAQ91075.1 - 1.4e-06 27.4 0.0 0.0059 15.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 EAQ91075.1 - 1.5e-06 28.5 0.0 0.086 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EAQ91075.1 - 2.2e-06 27.3 0.2 0.095 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EAQ91075.1 - 2.4e-06 27.4 0.0 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EAQ91075.1 - 3.6e-06 27.0 0.0 0.089 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EAQ91075.1 - 7.7e-06 24.9 0.1 0.043 12.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EAQ91075.1 - 1.2e-05 25.4 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EAQ91075.1 - 1.2e-05 25.0 0.0 4 7.0 0.0 3.9 2 2 1 3 3 3 0 Archaeal ATPase NACHT PF05729.7 EAQ91075.1 - 1.5e-05 24.6 0.1 0.085 12.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 EAQ91075.1 - 1.7e-05 24.3 0.0 0.17 11.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EAQ91075.1 - 2.3e-05 24.7 0.0 0.23 11.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 EAQ91075.1 - 6.1e-05 22.7 0.0 0.39 10.3 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein PhoH PF02562.11 EAQ91075.1 - 0.00013 21.2 0.2 0.5 9.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EAQ91075.1 - 0.00018 21.1 0.0 0.59 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EAQ91075.1 - 0.00018 21.1 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EAQ91075.1 - 0.00026 20.8 0.1 0.0013 18.5 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 EAQ91075.1 - 0.00047 19.1 0.1 0.55 9.0 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain AAA_11 PF13086.1 EAQ91075.1 - 0.00051 19.6 0.0 0.82 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 EAQ91075.1 - 0.00095 18.9 0.6 0.65 9.6 0.0 4.0 4 0 0 4 4 3 1 NTPase DUF2075 PF09848.4 EAQ91075.1 - 0.0016 17.4 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EAQ91075.1 - 0.0072 15.8 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EAQ91075.1 - 0.0076 15.2 0.4 1.4 7.8 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.11 EAQ91075.1 - 0.01 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 EAQ91075.1 - 0.017 14.7 0.1 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EAQ91075.1 - 0.027 13.9 0.5 1.6 8.1 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain Zot PF05707.7 EAQ91075.1 - 0.028 13.8 0.1 16 4.8 0.1 4.0 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) T2SE PF00437.15 EAQ91075.1 - 0.031 13.1 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EAQ91075.1 - 0.055 13.7 0.2 4.4 7.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain AFG1_ATPase PF03969.11 EAQ91075.1 - 0.082 11.7 0.0 9.5 4.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 EAQ91075.1 - 0.098 12.5 0.1 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 EAQ91075.1 - 0.098 12.3 0.8 3.5 7.3 0.0 3.3 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EAQ91075.1 - 0.11 11.6 0.4 11 5.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ERAP1_C PF11838.3 EAQ91076.1 - 0.077 12.2 0.2 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain EnY2 PF10163.4 EAQ91076.1 - 0.15 11.9 0.1 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Transcription factor e(y)2 Lsm_interact PF05391.6 EAQ91078.1 - 0.33 10.4 1.4 0.38 10.2 0.1 1.8 2 0 0 2 2 2 0 Lsm interaction motif DUF2742 PF10888.3 EAQ91079.1 - 0.034 14.0 0.4 0.045 13.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2742) ABC_tran PF00005.22 EAQ91080.1 - 1.3e-30 106.5 0.0 2.6e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EAQ91080.1 - 5.8e-24 84.9 2.9 5.8e-24 84.9 2.0 1.8 3 0 0 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.1 EAQ91080.1 - 0.0052 16.7 0.0 0.37 10.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAQ91080.1 - 0.0056 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EAQ91080.1 - 0.0078 16.1 0.4 0.16 11.9 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EAQ91080.1 - 0.022 14.2 0.1 0.054 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAM_LAG1_CLN8 PF03798.11 EAQ91081.1 - 1.1e-32 113.2 20.1 1.1e-32 113.2 13.9 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EAQ91081.1 - 3e-23 81.0 0.0 3e-23 81.0 0.0 2.3 3 0 0 3 3 3 1 TRAM1-like protein TrkH PF02386.11 EAQ91082.1 - 1.8e-92 309.6 8.6 4.6e-90 301.7 2.9 2.1 2 0 0 2 2 2 2 Cation transport protein Na_H_Exchanger PF00999.16 EAQ91083.1 - 7.1e-16 57.7 11.8 7.7e-09 34.5 0.9 3.0 2 1 1 3 3 3 3 Sodium/hydrogen exchanger family YrhC PF14143.1 EAQ91083.1 - 0.0029 17.5 0.1 0.0029 17.5 0.1 2.5 3 0 0 3 3 3 1 YrhC-like protein Choline_kinase PF01633.15 EAQ91085.1 - 0.097 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase PsbW PF07123.7 EAQ91085.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) PalH PF08733.5 EAQ91086.1 - 1.3e-112 376.1 0.0 1.5e-112 375.8 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 SPC25 PF06703.6 EAQ91086.1 - 1.1 8.8 2.7 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SH3_1 PF00018.23 EAQ91087.1 - 0.013 14.9 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 SH3 domain PIG-S PF10510.4 EAQ91087.1 - 3.1 6.3 7.0 5.2 5.6 4.8 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Polysacc_lyase PF14099.1 EAQ91088.1 - 0.0054 16.4 3.0 0.01 15.4 2.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase DUF1228 PF06779.9 EAQ91088.1 - 0.56 10.2 4.1 0.22 11.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Na_H_Exchanger PF00999.16 EAQ91089.1 - 7.9e-68 228.7 38.6 1e-67 228.3 26.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Misat_Tub_SegII PF10644.4 EAQ91091.1 - 2.7e-17 62.8 0.1 6.6e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EAQ91091.1 - 0.0003 20.2 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pyr_redox_2 PF07992.9 EAQ91092.1 - 2.5e-26 92.8 0.0 5.1e-17 62.4 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ91092.1 - 1.2e-13 51.2 0.0 1.8e-12 47.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ91092.1 - 0.0018 18.4 0.1 1.4 8.9 0.0 2.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fibrinogen_aC PF12160.3 EAQ91092.1 - 0.67 9.4 3.3 1.3 8.5 2.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain Glyco_hydro_18 PF00704.23 EAQ91094.1 - 4.2e-40 138.2 0.0 5.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EAQ91094.1 - 3.5e-13 49.2 0.0 2.6e-06 27.2 0.0 2.8 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 EAQ91094.1 - 0.00042 20.2 5.5 0.00042 20.2 3.8 3.5 5 0 0 5 5 5 1 Chitin recognition protein DUF3142 PF11340.3 EAQ91094.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Peptidase_S8 PF00082.17 EAQ91095.1 - 1.1e-05 24.7 0.0 2.4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PfkB PF00294.19 EAQ91096.1 - 9.8e-28 97.1 1.9 4.2e-15 55.6 0.2 2.8 1 1 1 2 2 2 2 pfkB family carbohydrate kinase MFS_1 PF07690.11 EAQ91097.1 - 9.2e-13 47.6 7.9 9.2e-13 47.6 5.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ91097.1 - 4.4e-06 25.5 2.5 8.7e-05 21.2 0.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CDK2AP PF09806.4 EAQ91097.1 - 0.017 15.3 0.7 0.028 14.6 0.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein WD40 PF00400.27 EAQ91099.1 - 3.4e-68 223.2 15.7 7e-13 47.9 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 EAQ91099.1 - 1.1e-14 54.4 0.3 2.2e-14 53.4 0.2 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EAQ91099.1 - 1.1e-08 33.7 11.5 0.044 11.9 0.0 5.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 EAQ91099.1 - 0.0006 19.4 6.9 4.1 7.1 0.0 6.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EAQ91099.1 - 0.00063 19.4 0.0 0.14 11.8 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EAQ91099.1 - 0.0011 17.7 4.7 3.1 6.4 0.7 4.3 1 1 3 4 4 4 2 Nup133 N terminal like AAA_22 PF13401.1 EAQ91099.1 - 0.035 14.2 0.0 0.43 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EAQ91099.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HARP PF07443.8 EAQ91099.1 - 0.063 12.6 1.1 39 3.7 0.0 4.5 4 0 0 4 4 4 0 HepA-related protein (HARP) RNA_helicase PF00910.17 EAQ91099.1 - 0.11 12.6 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase GATase PF00117.23 EAQ91099.1 - 0.29 10.5 0.0 0.58 9.5 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Pkinase_Tyr PF07714.12 EAQ91100.1 - 9.8e-18 64.1 0.0 6e-17 61.5 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EAQ91100.1 - 5.4e-17 61.7 0.0 1.2e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAQ91100.1 - 2.6e-05 23.3 0.0 5.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UvrD_C_2 PF13538.1 EAQ91100.1 - 7.3e-05 22.8 0.0 0.0003 20.8 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ91100.1 - 0.0016 18.5 0.3 0.051 13.6 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain RIO1 PF01163.17 EAQ91100.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EAQ91100.1 - 0.014 14.3 0.0 0.084 11.8 0.0 2.0 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EAQ91100.1 - 0.034 13.8 0.4 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family PAP_central PF04928.12 EAQ91101.1 - 2.1e-73 246.2 0.0 3.3e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EAQ91101.1 - 3.8e-19 68.7 0.1 7.9e-19 67.7 0.1 1.6 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EAQ91101.1 - 3.2e-07 30.5 0.0 1.1e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PGAP1 PF07819.8 EAQ91102.1 - 1.4e-05 24.7 0.2 2.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EAQ91102.1 - 8.4e-05 22.3 0.3 0.00018 21.2 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ91102.1 - 0.0014 18.5 0.8 0.0038 17.1 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAQ91102.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EAQ91102.1 - 0.0067 16.6 0.0 0.013 15.7 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EAQ91102.1 - 0.012 15.1 0.0 0.044 13.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAQ91102.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF676 PF05057.9 EAQ91102.1 - 0.12 11.7 0.0 0.48 9.6 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PTPLA PF04387.9 EAQ91103.1 - 2.1e-31 108.5 11.5 2.4e-30 105.1 8.0 2.1 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA tRNA-synt_2d PF01409.15 EAQ91105.1 - 9.6e-68 228.0 0.7 1.5e-66 224.1 0.2 2.5 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) Arf PF00025.16 EAQ91106.1 - 1.5e-72 242.4 0.1 1.8e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAQ91106.1 - 3.4e-12 45.9 0.0 4.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EAQ91106.1 - 2.5e-11 42.9 0.5 1.5e-07 30.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EAQ91106.1 - 4.2e-10 39.2 0.0 5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EAQ91106.1 - 2.1e-08 33.5 0.0 2.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAQ91106.1 - 2.2e-08 34.6 0.0 3.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAQ91106.1 - 3.8e-06 26.8 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAQ91106.1 - 0.00014 21.3 0.1 0.022 14.2 0.0 2.1 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EAQ91106.1 - 0.0012 17.6 0.4 0.0044 15.8 0.1 2.0 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 EAQ91106.1 - 0.03 13.6 0.6 0.14 11.3 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B VWA_CoxE PF05762.9 EAQ91106.1 - 0.061 12.4 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ribosomal_L39 PF00832.15 EAQ91107.1 - 1.1e-22 79.1 8.6 1.2e-22 79.0 6.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.14 EAQ91108.1 - 5e-40 135.4 2.1 8.4e-40 134.6 1.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EAQ91108.1 - 2.4e-19 69.1 0.0 5.9e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EAQ91108.1 - 0.021 14.7 0.8 0.021 14.7 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DFF-C PF09033.5 EAQ91108.1 - 0.044 13.6 0.3 0.063 13.1 0.2 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain DUF2346 PF09803.4 EAQ91110.1 - 0.00015 21.5 3.6 0.00031 20.5 2.5 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Transcrip_reg PF01709.15 EAQ91111.1 - 1.3e-62 210.9 0.5 1.5e-62 210.7 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator LPP20 PF02169.11 EAQ91111.1 - 0.05 13.6 0.0 0.27 11.3 0.0 2.1 2 1 0 2 2 2 0 LPP20 lipoprotein MutS_III PF05192.13 EAQ91111.1 - 0.092 12.5 0.4 1.3 8.7 0.0 2.4 2 1 1 3 3 3 0 MutS domain III AdoMetDC_leader PF08132.6 EAQ91111.1 - 0.54 10.2 3.0 18 5.3 0.3 3.1 3 0 0 3 3 3 0 S-adenosyl-l-methionine decarboxylase leader peptide HEAT_2 PF13646.1 EAQ91112.1 - 2.1e-14 53.5 16.8 0.00045 20.4 0.0 8.2 7 1 1 8 8 8 4 HEAT repeats HEAT PF02985.17 EAQ91112.1 - 2.6e-07 30.1 24.7 0.0099 15.8 0.1 10.8 12 0 0 12 12 12 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EAQ91112.1 - 2.7e-06 27.6 0.6 0.012 15.9 0.0 4.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EAQ91112.1 - 0.0002 20.8 0.1 0.44 9.8 0.0 4.3 3 1 0 3 3 3 1 CLASP N terminal IFRD PF05004.8 EAQ91112.1 - 0.0049 16.0 0.2 0.018 14.1 0.2 1.9 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EAQ91112.1 - 0.86 10.1 29.1 2.1 8.9 0.4 9.3 8 1 1 9 9 9 0 HEAT-like repeat DUF1640 PF07798.6 EAQ91113.1 - 4.8e-12 46.2 1.1 6.4e-12 45.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Abhydrolase_6 PF12697.2 EAQ91114.1 - 9.7e-18 64.8 0.2 1.6e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ91114.1 - 4.4e-11 42.7 0.0 1.5e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EAQ91114.1 - 4.6e-10 39.2 0.0 7.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EAQ91114.1 - 3e-08 33.4 0.0 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EAQ91114.1 - 0.0041 16.5 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EAQ91114.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 EAQ91114.1 - 0.021 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Y_phosphatase PF00102.22 EAQ91114.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PGAP1 PF07819.8 EAQ91114.1 - 0.04 13.5 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EAQ91114.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Alk_phosphatase PF00245.15 EAQ91115.1 - 1.8e-90 303.6 0.0 7.5e-51 173.1 0.0 2.1 1 1 0 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.13 EAQ91115.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily ATP-synt_8 PF00895.15 EAQ91115.1 - 0.078 13.1 0.9 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 ATP synthase protein 8 Fructosamin_kin PF03881.9 EAQ91117.1 - 0.00078 18.5 0.0 0.0015 17.5 0.0 1.4 2 0 0 2 2 2 1 Fructosamine kinase LRR_4 PF12799.2 EAQ91118.1 - 0.023 14.2 14.0 0.26 10.9 1.7 5.6 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) U3_assoc_6 PF08640.6 EAQ91118.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Rad9 PF04139.8 EAQ91119.1 - 1.8e-64 217.3 3.3 1.9e-47 161.5 0.1 2.1 1 1 1 2 2 2 2 Rad9 Rad1 PF02144.11 EAQ91119.1 - 0.014 14.2 0.3 0.025 13.3 0.2 1.4 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DUF605 PF04652.11 EAQ91119.1 - 0.14 11.5 7.6 0.19 11.0 5.3 1.3 1 0 0 1 1 1 0 Vta1 like RCC1 PF00415.13 EAQ91120.1 - 3.8e-11 43.0 0.1 6.4e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAQ91120.1 - 0.00081 18.9 3.2 0.0025 17.3 0.0 2.3 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.12 EAQ91121.1 - 1.5e-13 50.2 0.0 2.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Aminotran_5 PF00266.14 EAQ91122.1 - 6.2e-11 41.6 0.0 6.8e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EAQ91122.1 - 0.0031 15.8 0.1 0.017 13.4 0.0 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EAQ91122.1 - 0.0073 15.3 0.2 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ELFV_dehydrog PF00208.16 EAQ91124.1 - 3.7e-26 92.1 0.0 5.7e-22 78.4 0.0 2.6 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EAQ91124.1 - 2.1e-17 61.9 0.0 7.3e-17 60.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EAQ91124.1 - 5.2e-05 22.8 0.0 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_L32e PF01655.13 EAQ91127.1 - 2.5e-50 169.1 1.7 3.5e-50 168.6 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.26 EAQ91128.1 - 1.1e-22 79.5 4.0 2.5e-22 78.3 2.8 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EAQ91128.1 - 3.8e-13 49.2 15.9 5.5e-13 48.7 11.0 1.2 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EAQ91128.1 - 0.0016 18.1 2.7 0.27 10.9 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family CTDII PF01556.13 EAQ91128.1 - 0.015 15.1 0.1 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 DnaJ C terminal domain APP_E2 PF12925.2 EAQ91128.1 - 0.056 13.0 0.4 0.085 12.4 0.3 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein zf-CHY PF05495.7 EAQ91128.1 - 0.23 11.6 6.4 0.72 10.0 0.3 2.4 2 0 0 2 2 2 0 CHY zinc finger DZR PF12773.2 EAQ91128.1 - 1.3 8.8 7.9 6 6.7 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF1356 PF07092.7 EAQ91128.1 - 1.5 7.9 3.8 7.6 5.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) tRNA-synt_1c PF00749.16 EAQ91129.1 - 2.3e-45 154.6 0.0 1.3e-42 145.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Fmp27 PF10344.4 EAQ91130.1 - 4.6e-256 851.8 0.0 6.7e-256 851.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EAQ91130.1 - 4.6e-178 592.7 0.3 4.6e-178 592.7 0.2 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EAQ91130.1 - 4.3e-158 526.6 0.0 2.8e-157 523.9 0.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EAQ91130.1 - 1.9e-54 183.8 0.0 4e-54 182.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EAQ91130.1 - 8.4e-54 181.5 0.1 2.4e-53 180.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EAQ91130.1 - 1.8e-34 118.2 0.0 5.5e-34 116.7 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.16 EAQ91130.1 - 4.2e-25 87.7 0.0 9.4e-25 86.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EAQ91130.1 - 2.5e-06 27.0 0.0 6.5e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1664 PF07889.7 EAQ91130.1 - 0.22 11.3 0.8 5 6.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3431 PF11913.3 EAQ91131.1 - 9.1e-81 270.5 0.0 1.1e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RRM_6 PF14259.1 EAQ91133.1 - 5.4e-11 42.3 0.0 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ91133.1 - 2.2e-08 33.5 0.1 5.8e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ91133.1 - 1.2e-05 25.1 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HlyD PF00529.15 EAQ91133.1 - 0.0015 17.8 12.4 0.0022 17.3 8.6 1.1 1 0 0 1 1 1 1 HlyD family secretion protein Asp-B-Hydro_N PF05279.6 EAQ91133.1 - 0.57 9.9 18.1 0.85 9.4 12.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAPS PF04499.10 EAQ91133.1 - 0.8 8.2 4.1 1.2 7.7 2.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 EAQ91133.1 - 0.97 7.6 16.4 1.3 7.1 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1510 PF07423.6 EAQ91133.1 - 2.5 7.4 19.6 3.9 6.7 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EAQ91133.1 - 8.1 6.2 16.9 14 5.4 11.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTP_EFTU PF00009.22 EAQ91134.1 - 7.1e-41 139.7 0.0 1.3e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAQ91134.1 - 2.2e-13 49.8 0.0 5.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EAQ91134.1 - 1.2e-09 38.1 0.0 3.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EAQ91134.1 - 3.9e-07 29.8 0.0 8.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EAQ91134.1 - 3.1e-05 23.5 0.1 0.0013 18.2 0.0 2.9 3 0 0 3 3 3 1 Elongation factor G, domain IV Paf67 PF10255.4 EAQ91135.1 - 3.7e-156 520.0 0.1 4.4e-156 519.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EAQ91135.1 - 0.00081 19.1 0.1 0.11 12.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HBS1_N PF08938.5 EAQ91135.1 - 0.019 15.0 1.7 0.04 14.0 1.2 1.5 1 0 0 1 1 1 0 HBS1 N-terminus Rubredoxin PF00301.15 EAQ91136.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin Usp PF00582.21 EAQ91137.1 - 1.6e-11 44.5 0.4 1.7e-10 41.2 0.0 2.5 3 0 0 3 3 3 1 Universal stress protein family PIF1 PF05970.9 EAQ91138.1 - 4.8e-29 101.4 0.0 2.7e-22 79.2 0.0 2.5 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EAQ91138.1 - 2.7e-05 23.8 0.0 0.00034 20.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ91138.1 - 0.00077 19.5 0.0 0.0035 17.4 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ91138.1 - 0.0015 16.4 0.0 0.0022 15.8 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.1 EAQ91138.1 - 0.0022 17.7 0.1 0.0068 16.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain ABA_GPCR PF12430.3 EAQ91140.1 - 5e-54 182.4 0.0 6.4e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EAQ91140.1 - 1.9e-10 40.6 0.3 3e-09 36.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3735) NACHT PF05729.7 EAQ91141.1 - 4e-12 46.1 0.2 8.2e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 EAQ91141.1 - 0.007 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat UPF0079 PF02367.12 EAQ91141.1 - 0.056 13.0 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EAQ91141.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAQ91141.1 - 0.12 12.5 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Transferase PF02458.10 EAQ91142.1 - 2.2e-13 49.4 0.0 2.7e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Transferase family ATG16 PF08614.6 EAQ91143.1 - 3.1e-05 23.9 8.7 7.8e-05 22.5 6.0 1.7 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EAQ91143.1 - 8.3e-05 22.2 1.9 0.00021 20.9 1.1 1.8 2 0 0 2 2 2 1 IncA protein AAA_13 PF13166.1 EAQ91143.1 - 9.7e-05 21.0 1.6 9.7e-05 21.0 1.1 1.5 2 0 0 2 2 2 1 AAA domain SlyX PF04102.7 EAQ91143.1 - 0.00069 19.9 4.8 0.055 13.8 0.4 2.8 1 1 1 2 2 2 2 SlyX zf-CCHC PF00098.18 EAQ91143.1 - 0.0013 18.5 0.1 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle BRE1 PF08647.6 EAQ91143.1 - 0.011 15.6 2.9 0.027 14.4 2.0 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EAQ91143.1 - 0.013 14.7 0.4 0.022 13.9 0.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EAQ91143.1 - 0.014 14.0 1.8 0.028 13.1 1.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF869 PF05911.6 EAQ91143.1 - 0.02 13.1 0.4 0.025 12.8 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TMF_DNA_bd PF12329.3 EAQ91143.1 - 0.02 14.7 1.6 0.02 14.7 1.1 3.2 3 1 1 4 4 3 0 TATA element modulatory factor 1 DNA binding U3_assoc_6 PF08640.6 EAQ91143.1 - 0.02 14.6 0.7 0.043 13.5 0.5 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 WEMBL PF05701.6 EAQ91143.1 - 0.022 13.2 3.4 0.032 12.7 2.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF2450 PF10475.4 EAQ91143.1 - 0.039 12.8 2.1 0.069 12.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Retrotrans_gag PF03732.12 EAQ91143.1 - 0.053 13.6 0.8 0.94 9.5 0.1 3.0 2 1 0 2 2 2 0 Retrotransposon gag protein Baculo_PEP_C PF04513.7 EAQ91143.1 - 0.068 13.0 2.5 0.23 11.2 1.7 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 EAQ91143.1 - 0.11 11.9 2.5 0.19 11.1 0.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DivIC PF04977.10 EAQ91143.1 - 0.19 11.2 0.1 0.19 11.2 0.0 2.6 2 1 1 3 3 2 0 Septum formation initiator Tropomyosin PF00261.15 EAQ91143.1 - 0.2 10.7 6.5 0.35 9.9 4.5 1.3 1 0 0 1 1 1 0 Tropomyosin TMPIT PF07851.8 EAQ91143.1 - 0.23 10.5 0.7 6.6 5.6 0.0 2.3 3 0 0 3 3 2 0 TMPIT-like protein TBPIP PF07106.8 EAQ91143.1 - 0.47 9.9 4.9 2.1 7.8 0.8 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HAUS5 PF14817.1 EAQ91143.1 - 0.54 8.7 8.4 0.21 10.0 4.1 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 Syntaxin-6_N PF09177.6 EAQ91143.1 - 0.85 10.0 7.4 4.5 7.7 0.1 3.7 3 1 1 4 4 4 0 Syntaxin 6, N-terminal COG2 PF06148.6 EAQ91143.1 - 1.1 9.1 3.4 2.1 8.2 1.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Uds1 PF15456.1 EAQ91143.1 - 1.1 9.2 11.4 2.5 8.1 0.3 4.0 3 1 1 4 4 3 0 Up-regulated During Septation Nup54 PF13874.1 EAQ91143.1 - 1.8 8.1 9.1 0.23 11.1 2.0 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF2894 PF11445.3 EAQ91143.1 - 2.7 8.1 8.5 0.37 11.0 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) RVT_1 PF00078.22 EAQ91144.1 - 2.4e-20 72.7 0.0 5.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91144.1 - 1.6e-13 50.8 0.2 5.4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ91144.1 - 2.9e-09 36.4 2.4 6.8e-09 35.2 1.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IN_DBD_C PF00552.16 EAQ91144.1 - 0.016 14.6 2.2 0.069 12.6 0.2 2.6 2 0 0 2 2 2 0 Integrase DNA binding domain DUF605 PF04652.11 EAQ91145.1 - 0.69 9.2 11.6 0.82 8.9 8.0 1.1 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 EAQ91147.1 - 3.1e-20 72.1 0.0 4.8e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_4 PF12763.2 EAQ91148.1 - 0.00087 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand YSIRK_signal PF04650.12 EAQ91148.1 - 6.7 6.3 5.8 13 5.4 4.0 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide MAP65_ASE1 PF03999.7 EAQ91149.1 - 6.3e-68 229.8 16.0 6.3e-68 229.8 11.1 2.1 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) S1 PF00575.18 EAQ91152.1 - 1.6e-90 297.2 33.2 3.1e-16 59.2 0.1 13.4 13 1 0 13 13 13 12 S1 RNA binding domain Suf PF05843.9 EAQ91152.1 - 0.013 15.2 6.0 0.017 14.8 0.1 3.0 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 EAQ91152.1 - 0.029 13.2 0.6 0.36 9.6 0.1 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 EAQ91152.1 - 0.05 13.9 0.1 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ91152.1 - 0.34 11.6 4.2 46 5.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M16_C PF05193.16 EAQ91154.1 - 2.2e-54 183.9 0.0 4.4e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAQ91154.1 - 1.7e-41 141.4 0.0 3.1e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FHA PF00498.21 EAQ91155.1 - 1.6e-16 60.1 0.0 3.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EAQ91155.1 - 0.0023 17.7 7.1 0.0042 16.8 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAQ91155.1 - 0.015 15.4 4.0 0.025 14.6 2.8 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAQ91155.1 - 0.058 13.0 5.8 0.11 12.2 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ifi-6-16 PF06140.8 EAQ91155.1 - 0.15 11.8 1.1 0.3 10.8 0.8 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family zf-RING-like PF08746.6 EAQ91155.1 - 0.5 10.3 3.9 0.87 9.6 2.7 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EAQ91155.1 - 1 9.0 4.1 2 8.1 2.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.1 EAQ91155.1 - 4.6 7.3 7.9 8.6 6.4 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps16_N PF04841.8 EAQ91156.1 - 3.7e-92 308.9 0.0 4.6e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EAQ91156.1 - 8.4e-75 251.6 0.0 1.1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region ACR_tran PF00873.14 EAQ91156.1 - 0.062 10.7 0.0 0.086 10.2 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Clathrin PF00637.15 EAQ91156.1 - 0.17 11.4 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS ATG16 PF08614.6 EAQ91157.1 - 1.1e-47 162.3 10.4 1.3e-47 162.1 7.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EAQ91157.1 - 0.0038 16.6 11.1 0.0072 15.7 7.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF904 PF06005.7 EAQ91157.1 - 0.44 10.8 0.0 0.44 10.8 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) GAS PF13851.1 EAQ91157.1 - 1.9 7.6 16.8 0.33 10.1 9.1 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.6 EAQ91157.1 - 2.9 6.4 11.4 0.82 8.2 6.0 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 EAQ91157.1 - 7.2 7.0 11.2 42 4.5 1.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DOT1 PF08123.8 EAQ91158.1 - 3.4e-73 245.3 0.0 4.8e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EAQ91158.1 - 8.2e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91158.1 - 1.3e-05 24.8 0.1 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91158.1 - 0.0007 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Nucleo_P87 PF07267.6 EAQ91158.1 - 1.4 7.5 4.4 2 6.9 3.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Med3 PF11593.3 EAQ91158.1 - 6.6 5.8 10.4 9.6 5.3 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 EAQ91159.1 - 1.5e-19 70.1 0.0 6.7e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91159.1 - 1.7e-08 33.8 0.0 3.6e-08 32.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 EAQ91159.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 FHA domain PEP-utilisers_N PF05524.8 EAQ91160.1 - 0.08 12.7 0.1 0.08 12.7 0.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4449 PF14613.1 EAQ91161.1 - 3.5e-67 225.4 0.3 3.5e-67 225.4 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Lipin_N PF04571.9 EAQ91161.1 - 0.097 12.3 0.1 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 lipin, N-terminal conserved region DNA_ligase_A_M PF01068.16 EAQ91162.1 - 1.7e-44 151.6 0.0 3.8e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAQ91162.1 - 2.4e-34 118.6 0.0 4.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EAQ91162.1 - 2.3e-15 56.7 0.5 1.4e-14 54.2 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EAQ91162.1 - 6.1e-09 35.9 0.1 3.9e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 EAQ91162.1 - 0.006 16.2 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 EAQ91162.1 - 0.011 15.4 0.0 0.32 10.6 0.0 2.5 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.2 EAQ91162.1 - 0.17 11.7 0.1 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain UPRTase PF14681.1 EAQ91163.1 - 7.1e-73 244.2 0.0 8.1e-73 244.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EAQ91163.1 - 9.2e-06 25.3 0.1 2.8e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EAQ91163.1 - 0.031 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain tRNA-synt_1g PF09334.6 EAQ91164.1 - 2e-99 332.9 0.2 9e-71 238.5 0.2 2.9 1 1 1 2 2 2 2 tRNA synthetases class I (M) CRCB PF02537.10 EAQ91164.1 - 7.9e-28 96.6 12.6 5.2e-18 65.0 8.6 2.5 2 0 0 2 2 2 2 CrcB-like protein tRNA-synt_1 PF00133.17 EAQ91164.1 - 0.0014 16.6 5.2 0.16 9.9 0.0 4.0 4 1 1 5 5 5 3 tRNA synthetases class I (I, L, M and V) Lactamase_B PF00753.22 EAQ91165.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAQ91165.1 - 2.4e-06 27.2 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4526 PF15029.1 EAQ91165.1 - 0.8 9.2 3.5 1.2 8.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) DUF605 PF04652.11 EAQ91165.1 - 2.4 7.4 23.8 3.3 7.0 16.5 1.1 1 0 0 1 1 1 0 Vta1 like Tim54 PF11711.3 EAQ91165.1 - 4.2 5.8 11.0 6.4 5.2 7.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ketoacyl-synt PF00109.21 EAQ91166.1 - 1e-75 254.5 0.6 2.5e-75 253.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ91166.1 - 4.5e-60 202.4 0.0 1.2e-59 201.0 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EAQ91166.1 - 1.8e-46 158.6 0.0 3.3e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EAQ91166.1 - 3.3e-44 150.7 0.1 1.4e-43 148.6 0.0 2.3 2 0 0 2 2 1 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EAQ91166.1 - 4.5e-44 151.0 3.7 1.1e-37 130.0 0.5 2.8 2 1 1 3 3 3 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EAQ91166.1 - 6.3e-36 122.8 1.1 4.3e-35 120.1 0.2 2.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain MFS_1 PF07690.11 EAQ91166.1 - 3.8e-31 108.0 46.0 8.9e-31 106.8 31.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EAQ91166.1 - 6.4e-20 71.0 0.0 2.2e-19 69.3 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ91166.1 - 2.8e-14 54.1 0.0 1.6e-13 51.6 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EAQ91166.1 - 3.1e-06 27.3 0.1 9.6e-06 25.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EAQ91166.1 - 7.5e-06 26.3 0.0 2.8e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91166.1 - 1e-05 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91166.1 - 6.1e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EAQ91166.1 - 0.00028 20.6 0.2 0.00069 19.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EAQ91166.1 - 0.00051 20.4 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91166.1 - 0.0094 16.5 0.0 0.035 14.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain FSH1 PF03959.8 EAQ91167.1 - 1.4e-27 96.5 0.0 9.4e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EAQ91167.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RPE65 PF03055.10 EAQ91168.1 - 9.3e-113 377.3 0.0 1.4e-112 376.7 0.0 1.3 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zn_clus PF00172.13 EAQ91168.1 - 3.9e-05 23.4 6.7 9.3e-05 22.2 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.6 EAQ91169.1 - 1e-11 44.4 7.9 1e-11 44.4 5.5 1.7 2 0 0 2 2 2 1 CFEM domain VGLL4 PF15245.1 EAQ91169.1 - 0.045 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 YjeF_N PF03853.10 EAQ91171.1 - 6.8e-44 149.4 0.0 1.1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EAQ91171.1 - 5.4e-10 39.7 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 FDF domain VWA_2 PF13519.1 EAQ91171.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain PIF1 PF05970.9 EAQ91172.1 - 2.8e-52 177.8 0.3 1.8e-43 148.8 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ91172.1 - 8.9e-16 58.0 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ91172.1 - 6.4e-08 32.8 0.1 3.9e-07 30.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ91172.1 - 7.4e-08 32.0 0.1 2.7e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EAQ91172.1 - 1.2e-05 25.3 0.7 8.1e-05 22.7 0.1 2.6 2 1 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 EAQ91172.1 - 2.3e-05 24.5 0.4 8.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.9 EAQ91172.1 - 3e-05 22.0 0.3 0.00017 19.5 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 EAQ91172.1 - 6.8e-05 22.9 0.1 0.0003 20.8 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.22 EAQ91172.1 - 0.00086 19.6 0.1 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AFG1_ATPase PF03969.11 EAQ91172.1 - 0.0015 17.4 0.3 0.13 11.0 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase AAA_11 PF13086.1 EAQ91172.1 - 0.0026 17.3 0.2 0.071 12.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EAQ91172.1 - 0.0033 17.3 0.0 0.0096 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAQ91172.1 - 0.0034 16.9 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EAQ91172.1 - 0.0047 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 EAQ91172.1 - 0.0054 16.2 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EAQ91172.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.11 EAQ91172.1 - 0.0091 15.2 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 EAQ91172.1 - 0.0092 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EAQ91172.1 - 0.017 14.1 0.1 0.05 12.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EAQ91172.1 - 0.018 14.7 0.1 0.051 13.2 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EAQ91172.1 - 0.02 14.1 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EAQ91172.1 - 0.025 13.9 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Helicase_RecD PF05127.9 EAQ91172.1 - 0.03 13.9 0.0 0.076 12.6 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.9 EAQ91172.1 - 0.034 13.8 0.2 0.4 10.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EAQ91172.1 - 0.038 13.4 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 EAQ91172.1 - 0.042 13.5 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EAQ91172.1 - 0.044 13.2 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain TIP49 PF06068.8 EAQ91172.1 - 0.061 12.0 0.0 2.7 6.6 0.0 2.4 3 0 0 3 3 3 0 TIP49 C-terminus DUF815 PF05673.8 EAQ91172.1 - 0.074 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EAQ91172.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EAQ91172.1 - 0.083 12.5 0.2 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.2 EAQ91172.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 FAM70 PF14967.1 EAQ91172.1 - 0.14 11.3 2.8 0.23 10.6 1.9 1.3 1 0 0 1 1 1 0 FAM70 protein Adeno_IVa2 PF02456.10 EAQ91172.1 - 0.24 10.0 0.0 0.38 9.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Nha1_C PF08619.5 EAQ91173.1 - 3e-107 359.6 21.6 4.7e-107 358.9 15.0 1.3 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EAQ91173.1 - 3.2e-68 229.9 21.7 3.9e-68 229.7 15.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_60s PF00428.14 EAQ91173.1 - 0.16 12.4 11.1 0.31 11.4 0.3 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF21 PF01595.15 EAQ91173.1 - 4.1 6.6 18.1 0.011 15.0 2.9 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF21 Macoilin PF09726.4 EAQ91173.1 - 4.5 5.4 8.1 7.4 4.7 5.6 1.3 1 0 0 1 1 1 0 Transmembrane protein PP2C PF00481.16 EAQ91175.1 - 1.4e-62 211.4 0.2 3.3e-51 174.1 0.1 3.1 1 1 2 3 3 3 3 Protein phosphatase 2C Snf7 PF03357.16 EAQ91176.1 - 7.5e-37 126.3 16.4 1.2e-36 125.6 11.3 1.2 1 0 0 1 1 1 1 Snf7 V_ATPase_I PF01496.14 EAQ91176.1 - 0.01 13.7 1.5 0.012 13.5 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4309 PF14172.1 EAQ91176.1 - 0.026 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) DUF1768 PF08719.6 EAQ91176.1 - 0.11 12.2 1.0 0.18 11.5 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) DFF40 PF09230.5 EAQ91176.1 - 0.64 9.3 5.9 0.64 9.3 3.5 1.3 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa PspA_IM30 PF04012.7 EAQ91176.1 - 2.1 7.6 16.4 0.64 9.3 2.5 2.1 1 1 0 2 2 2 0 PspA/IM30 family CaMBD PF02888.11 EAQ91176.1 - 9.3 6.1 8.8 1.1 9.0 2.3 2.1 1 1 1 2 2 2 0 Calmodulin binding domain GTP_EFTU PF00009.22 EAQ91177.1 - 1.4e-05 24.6 0.1 3.9e-05 23.1 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAQ91177.1 - 6.5e-05 22.8 0.8 0.00021 21.1 0.1 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EAQ91177.1 - 0.0039 17.1 0.2 0.012 15.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase A_deaminase PF00962.17 EAQ91178.1 - 7.5e-15 54.6 0.0 1.1e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase WD40 PF00400.27 EAQ91179.1 - 3.3e-47 156.7 20.5 8.7e-10 38.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EAQ91179.1 - 0.00013 21.7 0.0 0.075 12.7 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Phosducin PF02114.11 EAQ91180.1 - 5.6e-10 38.3 0.7 3.3e-08 32.5 0.5 2.3 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.13 EAQ91182.1 - 8.6e-48 161.4 0.7 1.7e-47 160.4 0.5 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EAQ91182.1 - 6.9e-05 22.5 0.1 0.00041 20.0 0.1 2.0 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 EAQ91182.1 - 0.00044 19.8 1.7 0.00086 18.8 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PS-DH PF14765.1 EAQ91182.1 - 0.022 13.9 0.2 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase Chorion_2 PF03964.10 EAQ91182.1 - 0.053 14.0 1.3 0.091 13.3 0.9 1.4 1 0 0 1 1 1 0 Chorion family 2 NOA36 PF06524.7 EAQ91182.1 - 4.2 6.5 14.2 0.7 9.1 2.1 2.1 2 0 0 2 2 2 0 NOA36 protein YEATS PF03366.11 EAQ91183.1 - 1.5e-23 82.3 0.1 2.9e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 YEATS family Baculo_8kDa PF06096.6 EAQ91183.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein Zn_clus PF00172.13 EAQ91184.1 - 5.4e-07 29.4 11.8 8.9e-07 28.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EAQ91185.1 - 1.4e-17 63.2 0.3 1.6e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ91185.1 - 0.0008 20.3 0.6 0.0038 18.1 0.1 2.4 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain DrsE PF02635.10 EAQ91185.1 - 0.13 12.3 0.4 0.27 11.3 0.1 1.6 2 0 0 2 2 2 0 DsrE/DsrF-like family Aminotran_1_2 PF00155.16 EAQ91186.1 - 8.6e-57 192.7 0.0 1.8e-56 191.6 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EAQ91186.1 - 0.0075 15.4 0.0 0.018 14.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EAQ91186.1 - 0.059 12.0 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V DUF4211 PF13926.1 EAQ91187.1 - 2e-41 140.9 0.0 6.1e-41 139.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) SAM_2 PF07647.12 EAQ91188.1 - 5.6e-17 61.3 0.0 9.3e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAQ91188.1 - 5.5e-15 55.3 0.0 8.2e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EAQ91188.1 - 5.1e-14 52.5 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PAT1 PF09770.4 EAQ91189.1 - 0.064 11.4 7.0 0.094 10.9 4.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 EAQ91189.1 - 1.1 8.3 14.0 1.7 7.7 9.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GRAS PF03514.9 EAQ91189.1 - 2.1 6.9 4.8 3.1 6.4 3.3 1.1 1 0 0 1 1 1 0 GRAS domain family DUF4407 PF14362.1 EAQ91189.1 - 5.7 5.8 6.9 8.4 5.2 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpL_GvpF PF06386.6 EAQ91189.1 - 6.2 6.3 10.1 9.9 5.6 7.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF adh_short PF00106.20 EAQ91190.1 - 4.5e-28 98.2 6.6 6.2e-28 97.7 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ91190.1 - 6.9e-17 61.6 2.3 9.2e-17 61.2 1.6 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ91190.1 - 2e-09 37.5 0.0 5.4e-09 36.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ91190.1 - 6.2e-07 29.0 0.1 1.1e-06 28.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ91190.1 - 2.1e-05 23.5 0.0 3.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 EAQ91190.1 - 0.044 13.1 0.1 0.13 11.6 0.0 1.9 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_7 PF13241.1 EAQ91190.1 - 0.066 13.4 0.2 0.16 12.2 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EAQ91190.1 - 0.095 13.1 0.0 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dynamin_N PF00350.18 EAQ91194.1 - 1.6e-17 63.8 0.0 3.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAQ91194.1 - 1.2e-10 40.6 0.0 2.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EAQ91194.1 - 0.00021 21.1 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EAQ91194.1 - 0.016 15.2 0.0 0.47 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 EAQ91194.1 - 0.029 13.6 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 EAQ91194.1 - 0.065 13.7 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 EAQ91194.1 - 0.27 11.1 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Clr5 PF14420.1 EAQ91195.1 - 0.0087 15.9 0.7 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Clr5 domain zf-C2H2 PF00096.21 EAQ91195.1 - 0.45 10.9 6.0 0.15 12.4 1.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3435 PF11917.3 EAQ91198.1 - 8.5e-30 103.8 0.0 1.3e-23 83.4 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) MMR_HSR1 PF01926.18 EAQ91200.1 - 2.9e-09 36.8 0.0 2.2e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAQ91200.1 - 3.6e-06 26.2 0.0 0.086 11.9 0.0 2.6 2 0 0 2 2 2 2 AIG1 family DUF258 PF03193.11 EAQ91200.1 - 3.8e-06 26.1 0.0 1.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF4254 PF14063.1 EAQ91200.1 - 0.00038 20.0 0.4 0.00038 20.0 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4254) AAA_29 PF13555.1 EAQ91200.1 - 0.0016 17.9 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EAQ91200.1 - 0.005 15.3 2.8 0.013 14.0 2.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EAQ91200.1 - 0.0077 15.7 0.1 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 EAQ91200.1 - 0.0078 15.1 0.0 0.02 13.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EAQ91200.1 - 0.0085 15.5 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EAQ91200.1 - 0.016 15.2 0.1 0.13 12.2 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Septin PF00735.13 EAQ91200.1 - 0.02 13.9 0.0 0.064 12.2 0.0 1.9 1 1 0 1 1 1 0 Septin AAA_23 PF13476.1 EAQ91200.1 - 0.023 14.9 5.2 0.93 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EAQ91200.1 - 0.059 13.0 0.0 0.059 13.0 0.0 3.4 4 0 0 4 4 4 0 Archaeal ATPase RNA_helicase PF00910.17 EAQ91200.1 - 0.079 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EAQ91200.1 - 0.082 13.0 0.0 2 8.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EAQ91200.1 - 0.088 13.1 0.0 0.49 10.6 0.0 2.3 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 EAQ91200.1 - 1.2 8.9 4.1 1.6 8.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EAQ91200.1 - 7.7 6.2 6.8 11 5.8 0.0 3.4 4 1 0 4 4 4 0 Dynamin family Ribosomal_S13 PF00416.17 EAQ91201.1 - 5.3e-41 139.3 1.0 6.4e-41 139.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EAQ91201.1 - 0.0051 15.4 0.0 0.0061 15.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EAQ91201.1 - 0.067 13.2 0.2 0.2 11.7 0.1 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif PP28 PF10252.4 EAQ91201.1 - 0.18 11.8 1.7 0.21 11.6 0.4 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 SBDS_C PF09377.5 EAQ91202.1 - 2.2e-56 188.9 0.0 3.1e-56 188.4 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EAQ91202.1 - 6.1e-30 102.8 0.0 1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FlxA PF14282.1 EAQ91202.1 - 0.0035 17.2 1.5 0.0081 16.0 1.0 1.6 1 0 0 1 1 1 1 FlxA-like protein DARPP-32 PF05395.7 EAQ91202.1 - 0.016 15.3 0.9 0.023 14.8 0.6 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Peptidase_S10 PF00450.17 EAQ91203.1 - 1.4e-131 439.5 0.9 1.8e-131 439.1 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EAQ91203.1 - 3.5e-06 27.1 0.0 7.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EAQ91203.1 - 9.8e-05 22.3 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family PDEase_I PF00233.14 EAQ91204.1 - 3.6e-43 148.0 0.5 5.6e-40 137.5 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.24 EAQ91205.1 - 6.4e-75 251.7 0.0 2.8e-42 144.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ91205.1 - 4.1e-15 56.0 0.0 5.2e-07 29.3 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EAQ91205.1 - 5.3e-11 42.7 0.0 1.6e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 DUSP domain Peptidase_M16 PF00675.15 EAQ91206.1 - 1.2e-27 96.5 1.4 2.7e-27 95.3 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAQ91206.1 - 6.5e-20 71.5 0.2 2.3e-12 46.9 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain zf-CCHC PF00098.18 EAQ91207.1 - 0.00011 22.0 3.5 0.00016 21.4 2.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EAQ91207.1 - 0.014 14.9 1.6 0.025 14.0 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CHCC PF10276.4 EAQ91208.1 - 5.6e-15 54.8 1.6 1.5e-14 53.5 0.9 1.8 2 0 0 2 2 2 1 Zinc-finger domain COX5B PF01215.14 EAQ91208.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb AAA_19 PF13245.1 EAQ91208.1 - 0.075 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2_4 PF13894.1 EAQ91208.1 - 0.14 12.5 0.4 0.29 11.5 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Band_3_cyto PF07565.8 EAQ91210.1 - 6.8 6.1 22.2 2 7.8 6.0 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Methyltransf_18 PF12847.2 EAQ91211.1 - 2.4e-15 57.0 0.4 6e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91211.1 - 6.2e-10 38.8 0.0 2.9e-09 36.6 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ91211.1 - 2.6e-07 30.6 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91211.1 - 1.7e-06 27.8 0.2 1.7e-05 24.6 0.0 2.4 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91211.1 - 5.5e-06 26.7 0.0 4.2e-05 23.9 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ91211.1 - 7e-06 26.3 0.0 2.9e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91211.1 - 1.4e-05 25.4 0.5 3e-05 24.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EAQ91211.1 - 0.00066 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EAQ91211.1 - 0.0008 18.8 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EAQ91211.1 - 0.0074 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EAQ91211.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EAQ91211.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase HEAT PF02985.17 EAQ91212.1 - 1e-41 137.2 15.5 0.012 15.5 0.0 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 EAQ91212.1 - 7.9e-29 99.7 6.4 7.3e-07 29.3 0.0 7.4 4 3 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EAQ91212.1 - 9.2e-12 45.1 3.5 0.031 14.6 0.0 7.5 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EAQ91212.1 - 4.2e-10 39.8 11.1 0.16 12.4 0.1 9.2 8 2 3 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EAQ91212.1 - 9.5e-09 34.0 7.8 7.2e-05 21.2 0.4 4.8 3 2 0 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.3 EAQ91212.1 - 1.5e-05 24.4 1.6 0.93 8.7 0.2 4.4 2 1 1 3 3 3 3 CLASP N terminal DUF2435 PF10363.4 EAQ91212.1 - 0.00015 21.5 4.4 0.028 14.3 0.2 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 EAQ91212.1 - 0.0024 17.6 2.0 1.3 8.9 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 EAQ91212.1 - 0.0093 15.4 0.0 7.4 6.0 0.0 3.6 3 1 1 4 4 4 1 DNA alkylation repair enzyme MadL PF03817.8 EAQ91212.1 - 0.064 13.1 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Malonate transporter MadL subunit Proteasom_PSMB PF10508.4 EAQ91212.1 - 0.18 10.0 3.5 0.43 8.7 0.1 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EAQ91212.1 - 0.26 11.0 9.3 2.4 7.9 0.3 5.3 4 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Myotub-related PF06602.9 EAQ91213.1 - 3.7e-125 417.3 0.0 5e-125 416.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EAQ91213.1 - 0.0023 18.1 0.0 0.0088 16.3 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family G-alpha PF00503.15 EAQ91213.1 - 0.029 13.0 0.1 0.048 12.3 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Y_phosphatase PF00102.22 EAQ91213.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 EAQ91214.1 - 1.3e-16 60.5 0.1 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EAQ91214.1 - 2.7e-12 46.0 0.1 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EAQ91214.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 EAQ91215.1 - 5.7e-104 347.2 12.8 7.7e-104 346.8 8.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EAQ91215.1 - 2.5e-08 34.0 4.5 2.5e-08 34.0 3.1 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EAQ91215.1 - 2.8e-05 24.1 7.8 2.8e-05 24.1 5.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF2937 PF11157.3 EAQ91215.1 - 0.15 11.3 2.3 1.1 8.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2420 PF10336.4 EAQ91216.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EAQ91217.1 - 5.6e-19 68.2 0.0 8.4e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAQ91217.1 - 9e-08 31.9 0.1 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Apc4 PF12896.2 EAQ91218.1 - 7.5e-64 214.8 0.0 1.1e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PH PF00169.24 EAQ91219.1 - 0.0014 18.8 0.4 0.0064 16.6 0.2 2.3 2 1 0 2 2 2 1 PH domain GRAM PF02893.15 EAQ91219.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Adenylsucc_synt PF00709.16 EAQ91221.1 - 1.1e-150 501.9 0.0 1.3e-150 501.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase ELO PF01151.13 EAQ91222.1 - 3.5e-83 278.7 11.2 4.3e-83 278.4 7.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Permease PF02405.11 EAQ91222.1 - 0.045 13.2 7.6 0.1 12.0 5.3 1.5 1 0 0 1 1 1 0 Permease DUF1518 PF07469.7 EAQ91222.1 - 0.065 13.3 7.3 0.16 12.1 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) Synaptobrevin PF00957.16 EAQ91224.1 - 8.7e-15 54.0 0.5 1.4e-14 53.4 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EAQ91224.1 - 4.1e-14 51.8 0.0 8.3e-14 50.9 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain DUF4191 PF13829.1 EAQ91224.1 - 0.0057 15.7 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) MoaC PF01967.16 EAQ91225.1 - 5.5e-48 162.0 0.2 1.1e-47 161.1 0.1 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EAQ91225.1 - 3.2e-21 75.3 0.2 4.4e-13 49.0 0.1 2.5 1 1 1 2 2 2 2 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EAQ91225.1 - 9e-19 68.2 0.0 1.4e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EAQ91225.1 - 3.3e-05 24.0 0.0 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EAQ91225.1 - 0.00044 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain WD40 PF00400.27 EAQ91226.1 - 0.0029 17.4 5.8 15 5.6 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat RRM_6 PF14259.1 EAQ91227.1 - 4.1e-10 39.4 0.0 4.5e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ91227.1 - 5.9e-10 38.6 0.0 3.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ91227.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1183 PF06682.7 EAQ91227.1 - 1.7 8.1 8.7 3.8 7.0 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FAM75 PF14650.1 EAQ91227.1 - 5.4 6.2 18.1 9.2 5.5 12.5 1.3 1 0 0 1 1 1 0 FAM75 family Pex16 PF08610.5 EAQ91227.1 - 7.5 5.4 5.6 11 4.8 3.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3074 PF11274.3 EAQ91228.1 - 2e-61 206.8 5.4 3.7e-61 205.9 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3074) START PF01852.14 EAQ91228.1 - 0.0026 17.1 0.1 0.011 15.1 0.1 2.0 2 0 0 2 2 2 1 START domain IncA PF04156.9 EAQ91228.1 - 0.059 12.9 20.3 0.71 9.4 1.0 2.4 2 0 0 2 2 2 0 IncA protein DUF3535 PF12054.3 EAQ91229.1 - 2.7e-138 461.3 0.9 2.1e-128 428.7 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EAQ91229.1 - 1.1e-53 181.9 0.1 4.6e-51 173.3 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ91229.1 - 5.5e-14 51.7 0.0 1.3e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EAQ91229.1 - 6.1e-12 44.5 9.0 0.018 15.1 0.0 9.0 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EAQ91229.1 - 4.5e-06 26.9 0.9 0.14 12.5 0.0 4.0 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EAQ91229.1 - 6.5e-05 23.1 11.8 0.0049 17.1 0.0 7.0 8 2 1 9 9 9 1 HEAT repeats HEAT_EZ PF13513.1 EAQ91229.1 - 7.1e-05 23.1 4.9 11 6.6 0.0 8.0 7 0 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EAQ91229.1 - 0.011 15.1 1.0 1.7 7.9 0.4 3.5 3 1 0 3 3 3 0 CLASP N terminal SMC_N PF02463.14 EAQ91230.1 - 1.9e-61 207.1 14.2 3.2e-61 206.3 9.9 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAQ91230.1 - 3.5e-26 91.5 0.0 1.3e-25 89.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EAQ91230.1 - 1.2e-15 58.2 3.1 4.2e-07 30.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EAQ91230.1 - 3.2e-15 57.0 24.0 3.2e-15 57.0 16.7 7.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EAQ91230.1 - 0.0004 19.8 0.0 0.001 18.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EAQ91230.1 - 0.079 12.1 24.9 0.17 11.0 0.8 4.9 4 1 1 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EAQ91230.1 - 0.31 11.3 0.0 0.31 11.3 0.0 7.1 3 2 1 4 4 4 0 ABC transporter GAS PF13851.1 EAQ91230.1 - 7.3 5.7 112.9 0.0085 15.3 3.9 7.0 2 2 2 6 6 6 0 Growth-arrest specific micro-tubule binding CDC37_N PF03234.9 EAQ91231.1 - 9.2e-60 201.9 4.7 9.2e-60 201.9 3.3 2.8 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EAQ91231.1 - 9.7e-48 161.9 0.1 2.6e-47 160.4 0.1 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EAQ91231.1 - 2.3e-24 85.1 2.2 2.3e-24 85.1 1.5 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain DUF1268 PF06896.6 EAQ91231.1 - 0.059 13.7 0.8 0.059 13.7 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1268) DUF2762 PF10960.3 EAQ91231.1 - 0.061 13.0 0.4 0.061 13.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) RVT_1 PF00078.22 EAQ91232.1 - 2.7e-16 59.5 0.0 4.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_43 PF04616.9 EAQ91235.1 - 7.9e-44 149.8 9.8 1e-43 149.4 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EAQ91235.1 - 1.3e-29 102.8 3.3 3.7e-29 101.4 2.3 1.8 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EAQ91235.1 - 0.032 13.5 7.3 0.14 11.4 5.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Histone PF00125.19 EAQ91236.1 - 0.012 15.7 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF155 PF02582.9 EAQ91237.1 - 5.5e-56 189.2 0.1 8.3e-56 188.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 EAQ91238.1 - 2.8e-09 37.1 0.6 6.7e-09 35.8 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ91238.1 - 1.1e-08 35.2 1.6 1.1e-08 35.2 1.1 2.5 3 0 0 3 3 3 1 HMG-box domain DNase_NucA_NucB PF14040.1 EAQ91238.1 - 0.19 11.8 4.5 0.28 11.3 1.8 2.1 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Pox_Ag35 PF03286.9 EAQ91238.1 - 0.58 9.6 10.9 1.2 8.6 7.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cpn60_TCP1 PF00118.19 EAQ91239.1 - 1.9e-138 462.1 6.7 2.1e-138 461.9 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.7 EAQ91239.1 - 0.00037 20.2 0.4 0.0011 18.7 0.3 1.8 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor HAD PF12710.2 EAQ91239.1 - 0.074 13.2 0.2 0.25 11.4 0.2 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ACT PF01842.20 EAQ91239.1 - 0.31 10.5 2.5 0.55 9.7 0.0 2.8 3 0 0 3 3 3 0 ACT domain PH_10 PF15411.1 EAQ91241.1 - 3e-27 95.1 0.2 4.7e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EAQ91241.1 - 6.3e-10 38.9 0.1 2.2e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EAQ91241.1 - 3.8e-08 33.2 0.0 6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.24 EAQ91241.1 - 0.087 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 PH domain Collagen PF01391.13 EAQ91241.1 - 5.4 6.6 37.3 0.46 10.0 21.7 2.2 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 EAQ91242.1 - 4.7e-23 81.4 34.3 2.1e-22 79.3 23.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Saccharop_dh PF03435.13 EAQ91243.1 - 1.3e-17 63.8 0.0 2.7e-17 62.8 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EAQ91243.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.14 EAQ91244.1 - 3.8e-39 132.4 8.3 4.2e-39 132.2 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EAQ91244.1 - 0.0041 16.9 3.3 0.0061 16.3 2.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Thymidylat_synt PF00303.14 EAQ91244.1 - 0.017 14.1 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase zf-H2C2_2 PF13465.1 EAQ91244.1 - 0.031 14.5 1.3 0.89 9.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain A2L_zn_ribbon PF08792.5 EAQ91244.1 - 0.033 13.6 3.5 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain GCC2_GCC3 PF07699.8 EAQ91244.1 - 0.041 13.4 0.5 0.062 12.9 0.3 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 NCD3G PF07562.9 EAQ91244.1 - 0.044 13.4 1.4 0.067 12.9 1.0 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR OrfB_Zn_ribbon PF07282.6 EAQ91244.1 - 0.061 12.9 1.3 0.086 12.5 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1364 PF07102.7 EAQ91244.1 - 0.071 12.9 0.7 0.1 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Zn-ribbon_8 PF09723.5 EAQ91244.1 - 0.09 12.7 1.8 0.54 10.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Pox_F11 PF04943.7 EAQ91244.1 - 0.091 11.6 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Poxvirus F11 protein zf-BED PF02892.10 EAQ91244.1 - 0.13 12.0 6.1 2.3 8.0 0.5 2.3 1 1 1 2 2 2 0 BED zinc finger Sgf11 PF08209.6 EAQ91244.1 - 0.14 11.5 0.9 0.96 8.8 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Elf1 PF05129.8 EAQ91244.1 - 0.15 11.7 3.4 0.28 10.8 2.4 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EAQ91244.1 - 0.25 11.7 3.5 0.95 9.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type NOB1_Zn_bind PF08772.6 EAQ91244.1 - 0.33 10.7 3.7 2 8.3 2.6 2.1 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like C1_4 PF07975.7 EAQ91244.1 - 3 7.8 5.0 5.8 7.0 0.4 2.1 1 1 2 3 3 3 0 TFIIH C1-like domain PHD PF00628.24 EAQ91245.1 - 4.4e-10 39.0 6.4 4.4e-10 39.0 4.4 2.8 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EAQ91245.1 - 1.7e-08 34.1 20.2 2.1e-08 33.8 1.5 3.7 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EAQ91245.1 - 8.5e-07 29.0 10.1 0.00012 22.0 4.1 3.1 2 1 0 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 EAQ91245.1 - 1e-05 25.2 8.3 0.00099 18.9 0.7 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EAQ91245.1 - 6.9e-05 22.4 1.9 6.9e-05 22.4 1.4 3.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ91245.1 - 8.8e-05 22.1 1.9 8.8e-05 22.1 1.3 3.5 4 0 0 4 4 4 1 zinc-RING finger domain PHD_2 PF13831.1 EAQ91245.1 - 0.00027 20.1 1.3 0.00027 20.1 0.9 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EAQ91245.1 - 0.00056 19.5 1.8 0.00056 19.5 1.3 3.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 EAQ91245.1 - 0.00058 19.8 1.9 0.00058 19.8 1.3 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ91245.1 - 0.0013 18.3 4.2 0.0013 18.3 2.9 3.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 EAQ91245.1 - 0.011 15.0 1.0 0.043 13.1 0.7 2.0 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_4 PF14570.1 EAQ91245.1 - 0.28 10.8 4.0 0.27 10.8 0.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MRP-L46 PF11788.3 EAQ91246.1 - 1.6e-31 109.2 0.2 3.2e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 CAF1 PF04857.15 EAQ91247.1 - 1.1e-22 80.6 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF3716 PF12511.3 EAQ91248.1 - 0.0025 17.3 0.4 0.0054 16.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2076 PF09849.4 EAQ91252.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Nnf1 PF03980.9 EAQ91253.1 - 4.8e-32 110.1 0.4 1.7e-31 108.4 0.0 2.0 2 0 0 2 2 2 1 Nnf1 SPX PF03105.14 EAQ91253.1 - 0.035 13.8 0.6 0.05 13.3 0.4 1.2 1 0 0 1 1 1 0 SPX domain PH_9 PF15410.1 EAQ91254.1 - 2.3e-06 27.7 0.0 3.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain YonK PF09642.5 EAQ91254.1 - 0.14 11.8 0.1 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 YonK protein NTF2 PF02136.15 EAQ91255.1 - 1.6e-21 76.8 0.2 2.5e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EAQ91255.1 - 1.3e-08 34.3 0.1 2.5e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ91255.1 - 3.6e-06 26.8 0.2 7.8e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAQ91255.1 - 0.00024 20.9 0.0 0.00057 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 EAQ91255.1 - 0.013 15.3 0.1 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EAQ91255.1 - 0.12 10.5 29.2 0.15 10.3 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EAQ91255.1 - 2.8 7.2 39.7 4.4 6.6 27.5 1.2 1 0 0 1 1 1 0 Vta1 like Fungal_trans_2 PF11951.3 EAQ91256.1 - 0.00031 19.4 0.0 0.0032 16.1 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain OHCU_decarbox PF09349.5 EAQ91257.1 - 0.051 13.8 0.0 0.086 13.1 0.0 1.3 1 0 0 1 1 1 0 OHCU decarboxylase zf-C3HC4_2 PF13923.1 EAQ91258.1 - 0.0023 17.9 1.9 0.0035 17.3 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ91258.1 - 0.031 13.9 1.8 0.049 13.2 1.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 EAQ91259.1 - 5.7e-41 138.1 0.1 2.6e-12 46.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EAQ91259.1 - 0.27 11.6 1.4 0.3 11.4 0.1 1.7 2 0 0 2 2 2 0 YtxH-like protein MULE PF10551.4 EAQ91260.1 - 1.5e-18 66.7 0.1 4e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ91260.1 - 0.00015 20.4 0.1 0.00027 19.6 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family CHORD PF04968.7 EAQ91260.1 - 0.095 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 CHORD SCA7 PF08313.7 EAQ91261.1 - 1.6e-33 114.0 0.3 1.6e-33 114.0 0.2 2.4 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-BED PF02892.10 EAQ91261.1 - 0.061 13.0 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 BED zinc finger Pkinase PF00069.20 EAQ91262.1 - 1.3e-75 253.8 0.0 1.6e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91262.1 - 2.3e-37 128.5 0.0 2.9e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ91262.1 - 0.0063 15.5 0.0 0.021 13.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EAQ91262.1 - 0.035 13.8 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EAQ91262.1 - 0.067 12.2 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M28 PF04389.12 EAQ91263.1 - 2.9e-39 134.6 0.0 3.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Dynamin_N PF00350.18 EAQ91266.1 - 2.3e-17 63.3 0.0 5.3e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EAQ91266.1 - 1.1e-05 25.3 0.0 0.0013 18.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EAQ91266.1 - 0.00023 21.4 0.0 0.0015 18.7 0.0 2.3 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EAQ91266.1 - 0.001 18.2 0.0 0.0022 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAQ91266.1 - 0.0049 17.0 0.0 0.28 11.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAQ91266.1 - 0.007 15.4 0.0 0.025 13.6 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EAQ91266.1 - 0.0071 16.1 0.4 0.0071 16.1 0.3 2.0 2 1 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EAQ91266.1 - 0.0094 16.4 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SMC_N PF02463.14 EAQ91266.1 - 0.0097 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AIG1 PF04548.11 EAQ91266.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family PRK PF00485.13 EAQ91266.1 - 0.013 15.1 0.1 0.024 14.1 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EAQ91266.1 - 0.016 15.2 0.4 0.046 13.7 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EAQ91266.1 - 0.02 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EAQ91266.1 - 0.042 12.6 0.0 0.09 11.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EAQ91266.1 - 0.044 14.6 0.9 0.33 11.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain TBPIP PF07106.8 EAQ91266.1 - 0.056 12.9 1.6 0.21 11.1 0.2 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) cobW PF02492.14 EAQ91266.1 - 0.095 12.1 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EAQ91266.1 - 0.097 11.2 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein ArgK PF03308.11 EAQ91266.1 - 0.098 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein ATP-synt_DE PF00401.15 EAQ91266.1 - 0.15 12.0 3.0 2.1 8.3 0.1 2.9 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NUDIX_2 PF13869.1 EAQ91267.1 - 1.2e-81 272.5 0.0 1.4e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EAQ91267.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) ABC_membrane PF00664.18 EAQ91268.1 - 7.3e-83 278.1 30.8 9.6e-45 153.1 7.8 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ91268.1 - 6e-27 94.6 1.4 4.1e-16 59.5 0.0 3.5 2 1 0 3 3 3 2 ABC transporter DUF258 PF03193.11 EAQ91268.1 - 4.3e-05 22.7 0.3 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ91268.1 - 0.00012 22.1 0.0 0.65 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EAQ91268.1 - 0.00026 20.9 0.6 0.56 10.1 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EAQ91268.1 - 0.0007 19.0 0.3 0.8 9.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ91268.1 - 0.00095 19.5 0.3 0.2 11.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EAQ91268.1 - 0.0018 18.7 0.3 3.8 8.0 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 EAQ91268.1 - 0.0021 17.5 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EAQ91268.1 - 0.018 14.2 0.9 1.3 8.1 0.2 2.7 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EAQ91268.1 - 0.073 11.9 0.6 0.21 10.4 0.1 1.9 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 EAQ91268.1 - 0.074 13.8 0.0 13 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAQ91268.1 - 0.079 12.7 1.4 0.73 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EAQ91268.1 - 0.095 12.5 1.7 4.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 EAQ91268.1 - 0.13 11.6 0.1 9.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 EAQ91268.1 - 0.16 11.6 0.2 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EAQ91268.1 - 0.2 11.5 0.7 18 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4398 PF14346.1 EAQ91268.1 - 2.2 8.3 7.0 28 4.8 4.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF2841 PF11001.3 EAQ91270.1 - 2.1e-39 134.2 0.2 2.1e-39 134.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) DUF2431 PF10354.4 EAQ91271.1 - 2.1e-52 177.4 0.0 2.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EAQ91271.1 - 0.00072 19.5 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NOA36 PF06524.7 EAQ91271.1 - 1.3 8.2 18.6 1.9 7.6 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.6 EAQ91271.1 - 8.3 6.2 27.5 33 4.2 0.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ThiF PF00899.16 EAQ91273.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family eIF-6 PF01912.13 EAQ91275.1 - 1e-81 272.7 0.9 1.6e-81 272.1 0.6 1.3 1 0 0 1 1 1 1 eIF-6 family Macoilin PF09726.4 EAQ91276.1 - 0.0057 15.0 0.8 0.0057 15.0 0.6 1.9 1 1 1 2 2 2 1 Transmembrane protein DUF812 PF05667.6 EAQ91276.1 - 1.2 7.5 6.6 0.19 10.2 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Pol_alpha_B_N PF08418.5 EAQ91276.1 - 9.4 5.6 19.3 4.4 6.7 0.8 2.7 2 1 1 3 3 3 0 DNA polymerase alpha subunit B N-terminal CAF1 PF04857.15 EAQ91277.1 - 1e-43 149.5 0.0 2.7e-38 131.7 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 EAQ91277.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain CLTH PF10607.4 EAQ91278.1 - 8.5e-39 132.5 0.0 1.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EAQ91278.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 LisH HLH PF00010.21 EAQ91279.1 - 4e-10 39.2 0.0 9.4e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 EAQ91279.1 - 0.11 11.9 0.9 0.24 10.9 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Aminotran_3 PF00202.16 EAQ91280.1 - 8.6e-94 314.1 0.0 1e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EAQ91280.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SET PF00856.23 EAQ91281.1 - 1.8e-23 83.6 0.2 1.9e-22 80.3 0.1 2.7 1 1 0 1 1 1 1 SET domain SRI PF08236.6 EAQ91281.1 - 8.4e-14 51.2 4.0 2e-13 50.0 2.8 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 EAQ91281.1 - 9.3e-07 28.5 1.5 2.3e-06 27.3 1.0 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 EAQ91281.1 - 0.0016 17.9 0.0 0.0044 16.5 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Terpene_synth PF01397.16 EAQ91281.1 - 0.081 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain AT_hook PF02178.14 EAQ91282.1 - 0.034 13.7 2.0 0.034 13.7 1.4 2.7 2 0 0 2 2 2 0 AT hook motif XPC-binding PF09280.6 EAQ91284.1 - 2.5e-24 84.4 10.0 4.4e-24 83.7 6.9 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EAQ91284.1 - 1.2e-17 63.0 0.7 1.9e-17 62.4 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EAQ91284.1 - 5.1e-14 51.6 5.0 4.8e-08 32.6 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EAQ91284.1 - 1.2e-08 34.5 0.6 2.1e-08 33.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAQ91284.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UBA_3 PF09288.5 EAQ91284.1 - 0.028 14.0 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain MCM_N PF14551.1 EAQ91284.1 - 0.032 14.7 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 MCM N-terminal domain Rad60-SLD_2 PF13881.1 EAQ91284.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like eIF-5a PF01287.15 EAQ91284.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold NUDE_C PF04880.8 EAQ91284.1 - 0.22 11.8 2.4 0.36 11.1 1.7 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TFIIA PF03153.8 EAQ91284.1 - 3.2 7.5 11.8 4.9 6.9 8.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.26 EAQ91285.1 - 5.2e-09 36.0 0.0 9.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAQ91285.1 - 0.006 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 EAQ91286.1 - 3.5e-30 103.8 6.5 3.5e-30 103.8 4.5 6.5 4 2 1 5 5 5 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EAQ91286.1 - 0.0054 15.9 2.2 0.0054 15.9 1.6 4.3 3 1 2 5 5 5 3 Reovirus sigma C capsid protein NYD-SP28_assoc PF14775.1 EAQ91286.1 - 1.4 8.6 10.6 0.84 9.3 0.3 4.6 3 1 0 3 3 3 0 Sperm tail C-terminal domain Baculo_PEP_C PF04513.7 EAQ91286.1 - 5.2 6.8 27.4 0.15 11.8 2.5 5.3 4 1 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.16 EAQ91286.1 - 7.4 6.6 52.7 0.37 10.7 1.2 10.3 7 3 4 12 12 12 0 bZIP transcription factor Totivirus_coat PF05518.6 EAQ91287.1 - 0.97 7.1 10.2 1.2 6.8 7.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein ABC_membrane PF00664.18 EAQ91288.1 - 2.5e-71 240.3 38.5 9.8e-45 153.0 13.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ91288.1 - 8e-51 171.9 0.0 1e-29 103.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EAQ91288.1 - 9.4e-09 34.6 3.0 0.00024 20.5 0.3 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAQ91288.1 - 5.9e-08 32.9 0.0 0.0011 18.9 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EAQ91288.1 - 6.3e-07 30.2 0.0 0.065 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EAQ91288.1 - 1.7e-06 28.2 0.1 0.26 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAQ91288.1 - 9.2e-06 24.9 0.1 0.11 11.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAQ91288.1 - 2.2e-05 23.9 0.2 0.19 11.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EAQ91288.1 - 0.00054 18.6 1.0 0.013 14.0 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.1 EAQ91288.1 - 0.0015 18.3 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAQ91288.1 - 0.0025 17.9 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAQ91288.1 - 0.0029 17.3 1.0 13 5.4 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EAQ91288.1 - 0.0029 17.9 0.1 3.8 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EAQ91288.1 - 0.004 17.1 0.3 0.7 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EAQ91288.1 - 0.0063 15.2 0.0 2.4 6.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.1 EAQ91288.1 - 0.024 14.5 0.0 5.2 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAQ91288.1 - 0.03 14.0 0.1 9.3 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EAQ91288.1 - 0.034 14.1 0.0 12 5.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EAQ91288.1 - 0.055 12.6 0.0 5.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EAQ91288.1 - 0.063 13.4 0.6 20 5.3 0.1 3.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EAQ91288.1 - 0.077 12.4 1.1 12 5.2 0.4 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EAQ91288.1 - 0.13 11.6 1.2 15 4.9 0.2 2.6 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 EAQ91288.1 - 1 9.1 6.6 4.2 7.1 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function DUF87 SMC_N PF02463.14 EAQ91288.1 - 1.1 8.4 4.1 7.1 5.7 0.2 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAQ91288.1 - 1.6 8.9 7.3 9.2 6.5 0.8 3.2 3 0 0 3 3 3 0 AAA domain Ribosomal_L10 PF00466.15 EAQ91289.1 - 9.6e-08 31.8 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 EAQ91290.1 - 9.8e-33 112.3 1.4 1.6e-32 111.6 1.0 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EAQ91290.1 - 4.8e-16 58.1 0.1 2.3e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ91290.1 - 6.3e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ91290.1 - 2.6e-08 33.5 0.0 6.1e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 EAQ91291.1 - 1.6e-14 53.3 0.0 2.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.13 EAQ91292.1 - 6.9e-93 310.1 1.2 7.8e-93 310.0 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EAQ91292.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 CutC family U3_snoRNA_assoc PF08297.6 EAQ91293.1 - 1.8e-16 60.1 2.4 1.8e-16 60.1 1.7 3.0 3 0 0 3 3 3 1 U3 snoRNA associated TPR_11 PF13414.1 EAQ91294.1 - 0.0047 16.5 0.3 0.053 13.1 0.1 2.2 1 1 0 2 2 2 1 TPR repeat RecO_C PF02565.10 EAQ91294.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 Recombination protein O C terminal TPR_1 PF00515.23 EAQ91294.1 - 0.058 13.0 0.1 0.57 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91294.1 - 0.064 13.2 0.1 0.46 10.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1759 PF03564.10 EAQ91294.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) TPR_8 PF13181.1 EAQ91294.1 - 0.12 12.1 0.0 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Med3 PF11593.3 EAQ91294.1 - 0.77 8.9 5.0 0.39 9.8 1.9 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 EAQ91296.1 - 0.25 11.3 5.7 0.8 9.7 3.9 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cullin PF00888.17 EAQ91297.1 - 3.1e-109 366.1 0.0 4.5e-109 365.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAQ91297.1 - 2.1e-27 94.6 0.2 4.7e-27 93.5 0.2 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain PQ-loop PF04193.9 EAQ91298.1 - 1.4e-41 139.8 8.4 3.4e-21 74.5 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat ECH PF00378.15 EAQ91299.1 - 4.2e-22 78.4 0.0 1.2e-21 76.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TPR_10 PF13374.1 EAQ91300.1 - 1.2e-73 241.1 0.0 1.7e-13 49.9 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ91300.1 - 7.8e-68 224.4 1.7 2.7e-18 65.6 0.0 4.7 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ91300.1 - 2.1e-23 80.2 3.5 3.3e-05 23.3 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91300.1 - 1.4e-17 62.1 0.2 0.0074 16.1 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ91300.1 - 1.8e-14 52.6 2.4 0.038 14.1 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ91300.1 - 3e-14 52.4 0.3 0.0004 19.9 0.0 4.2 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EAQ91300.1 - 3.8e-14 51.5 0.0 0.014 14.9 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ91300.1 - 2.7e-12 46.9 0.1 0.0035 17.9 0.0 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ91300.1 - 4.1e-11 42.1 0.0 5 7.8 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ91300.1 - 2.9e-10 39.8 5.4 1.8 9.4 0.0 7.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ91300.1 - 1e-09 37.4 0.1 0.26 11.1 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ91300.1 - 1.6e-09 37.0 0.0 3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EAQ91300.1 - 7.9e-09 35.7 1.5 0.13 12.6 0.0 5.2 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_5 PF12688.2 EAQ91300.1 - 7.8e-08 32.3 0.1 0.12 12.3 0.0 3.9 1 1 2 3 3 3 2 Tetratrico peptide repeat PPR PF01535.15 EAQ91300.1 - 5.7e-07 29.0 2.1 0.59 10.2 0.0 4.9 5 0 0 5 5 4 1 PPR repeat Apc3 PF12895.2 EAQ91300.1 - 7.5e-07 29.2 0.0 0.016 15.3 0.0 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAQ91300.1 - 9.6e-07 28.8 5.0 1.1 9.8 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat PPR_3 PF13812.1 EAQ91300.1 - 4.8e-06 26.4 3.6 1.3 9.4 0.0 5.2 5 0 0 5 5 4 1 Pentatricopeptide repeat domain NACHT PF05729.7 EAQ91300.1 - 0.00025 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF4074 PF13293.1 EAQ91300.1 - 0.0013 18.9 0.0 28 5.0 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4074) Rab5-bind PF09311.6 EAQ91300.1 - 0.003 17.4 0.3 7.6 6.3 0.0 3.3 1 1 2 3 3 3 0 Rabaptin-like protein PPR_2 PF13041.1 EAQ91300.1 - 0.0033 17.3 0.7 9.3 6.3 0.0 4.1 3 1 1 4 4 4 0 PPR repeat family TPR_20 PF14561.1 EAQ91300.1 - 0.0036 17.3 0.5 17 5.6 0.0 4.5 1 1 4 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 EAQ91300.1 - 0.0072 15.8 0.8 0.93 8.9 0.0 3.4 2 1 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) AAA_25 PF13481.1 EAQ91300.1 - 0.0074 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Granin PF01271.12 EAQ91300.1 - 0.01 14.5 0.6 1.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Granin (chromogranin or secretogranin) SnoaL_4 PF13577.1 EAQ91300.1 - 0.054 13.4 0.2 5 7.0 0.0 3.3 2 1 0 2 2 2 0 SnoaL-like domain AAA_22 PF13401.1 EAQ91300.1 - 0.083 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.14 EAQ91301.1 - 1.1e-46 158.7 0.0 1.7e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease GCR1_C PF12550.3 EAQ91301.1 - 8.6e-23 80.0 0.4 2.6e-22 78.4 0.3 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_psq PF05225.11 EAQ91301.1 - 2.6e-13 49.2 0.0 5.6e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ91301.1 - 2.4e-08 33.6 0.1 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ91301.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D DUF904 PF06005.7 EAQ91301.1 - 0.12 12.6 2.2 0.75 10.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) MULE PF10551.4 EAQ91302.1 - 3.7e-19 68.6 0.0 1.1e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain NUDIX-like PF09296.6 EAQ91302.1 - 1.9e-18 66.5 0.0 1.2e-17 64.0 0.0 2.3 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EAQ91302.1 - 3.8e-16 58.9 0.1 8.2e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EAQ91302.1 - 2.9e-09 36.2 2.1 6.4e-09 35.1 1.5 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Transposase_mut PF00872.13 EAQ91302.1 - 0.0001 20.9 0.0 0.00026 19.6 0.0 1.6 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 EAQ91302.1 - 0.0065 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.10 EAQ91302.1 - 0.028 13.9 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 MuDR family transposase Ribosomal_L1 PF00687.16 EAQ91303.1 - 2.5e-37 128.3 0.6 2.9e-37 128.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.9 EAQ91303.1 - 0.09 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family Zn_clus PF00172.13 EAQ91305.1 - 3e-06 27.0 8.0 5.8e-06 26.1 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EAQ91305.1 - 0.73 9.1 26.8 1 8.6 18.6 1.2 1 0 0 1 1 1 0 Vta1 like zf-C2H2_4 PF13894.1 EAQ91309.1 - 0.0047 17.1 14.4 0.0064 16.7 0.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ91309.1 - 0.0081 16.4 4.7 0.69 10.3 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Isochorismatase PF00857.15 EAQ91310.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 EAQ91310.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Kinetochor_Ybp2 PF08568.5 EAQ91311.1 - 7.3e-99 331.7 0.2 1e-98 331.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.15 EAQ91312.1 - 3e-14 52.9 0.1 8.1e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EAQ91312.1 - 4.5e-08 32.0 0.0 7.5e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EAQ91312.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CDC45 PF02724.9 EAQ91312.1 - 0.43 8.5 19.4 1.1 7.2 6.5 2.4 3 0 0 3 3 3 0 CDC45-like protein DUF4632 PF15451.1 EAQ91312.1 - 5.2 7.0 12.6 1.9 8.4 1.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Peptidase_M66 PF10462.4 EAQ91313.1 - 6.4 5.5 8.3 9.7 4.9 5.8 1.2 1 0 0 1 1 1 0 Peptidase M66 COesterase PF00135.23 EAQ91314.1 - 6.5e-71 239.6 0.0 1.1e-70 238.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ91314.1 - 3.5e-11 43.0 0.1 9.6e-11 41.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ91314.1 - 0.0094 15.1 0.5 0.017 14.3 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ91314.1 - 0.034 13.8 0.2 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family HeLo PF14479.1 EAQ91315.1 - 1.8e-31 109.5 5.0 4.6e-18 65.7 0.1 2.3 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EAQ91315.1 - 2.3e-05 23.5 0.2 0.00019 20.6 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAQ91315.1 - 0.001 18.2 0.0 0.003 16.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain ABC2_membrane PF01061.19 EAQ91316.1 - 4.3e-17 61.9 18.5 7.6e-17 61.1 12.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EAQ91316.1 - 1.3e-14 54.7 0.1 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Zn_clus PF00172.13 EAQ91316.1 - 7.5e-06 25.7 2.6 1.7e-05 24.6 1.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ91316.1 - 3.4e-05 22.8 0.0 0.00013 20.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_16 PF13191.1 EAQ91316.1 - 0.0051 16.8 0.3 0.016 15.2 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF2763 PF10961.3 EAQ91316.1 - 0.078 13.3 4.7 2.5 8.5 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) AAA_22 PF13401.1 EAQ91316.1 - 0.13 12.4 0.4 0.48 10.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain NDUFA12 PF05071.11 EAQ91317.1 - 7.1e-05 23.2 0.2 0.0075 16.7 0.2 2.5 2 0 0 2 2 2 2 NADH ubiquinone oxidoreductase subunit NDUFA12 Asp-B-Hydro_N PF05279.6 EAQ91318.1 - 3.1 7.6 33.7 4.4 7.0 23.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DNA_pol_A PF00476.15 EAQ91319.1 - 1.4e-80 270.8 0.0 2.2e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.1 EAQ91320.1 - 1.4e-11 43.8 8.5 2.1e-11 43.2 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ91320.1 - 1.6e-09 37.4 9.8 2.6e-09 36.7 6.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ91320.1 - 9.3e-08 31.9 10.2 1.6e-07 31.2 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ91320.1 - 3.3e-07 29.9 8.4 5.2e-07 29.2 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAQ91320.1 - 4.2e-07 29.5 9.6 6.9e-07 28.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ91320.1 - 0.0012 18.6 7.8 0.0024 17.7 5.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAQ91320.1 - 0.0033 16.9 5.7 0.0059 16.1 3.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EAQ91320.1 - 0.0037 17.0 3.3 0.0065 16.2 2.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EAQ91320.1 - 0.058 13.1 9.5 2.1 8.1 6.6 2.9 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EAQ91320.1 - 0.072 12.6 7.8 0.5 9.9 5.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 M-factor PF03855.8 EAQ91320.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 M-factor zf-rbx1 PF12678.2 EAQ91320.1 - 0.54 10.4 7.1 1.3 9.2 4.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger DUF3414 PF11894.3 EAQ91321.1 - 0 1477.0 0.0 1.7e-260 867.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EAQ91322.1 - 3.1e-40 138.1 0.0 9e-40 136.5 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EAQ91322.1 - 2.1e-36 125.0 0.1 2.9e-35 121.2 0.0 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 EAQ91322.1 - 3.8e-25 88.6 9.1 9.3e-25 87.3 6.3 1.6 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 EAQ91322.1 - 2.5e-11 42.7 0.3 9.7e-11 40.9 0.1 2.2 2 0 0 2 2 2 1 FATC domain Connexin43 PF03508.8 EAQ91322.1 - 0.2 10.9 0.7 0.48 9.7 0.5 1.6 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) SNF5 PF04855.7 EAQ91323.1 - 2.6e-50 171.1 1.4 2e-42 145.3 0.7 2.3 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 EAQ91324.1 - 3.7e-09 36.4 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 EAQ91325.1 - 6.8e-14 51.3 16.5 2.3e-08 33.5 5.2 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EAQ91325.1 - 0.0038 16.9 6.0 0.36 10.5 0.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EAQ91325.1 - 0.026 14.6 6.4 0.18 11.9 1.7 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EAQ91325.1 - 0.055 12.7 10.4 0.35 10.1 3.1 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EAQ91325.1 - 0.057 13.1 10.7 0.028 14.1 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 YtxH PF12732.2 EAQ91325.1 - 0.067 13.5 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 YtxH-like protein zf-HC5HC2H_2 PF13832.1 EAQ91325.1 - 0.42 10.6 3.2 2.3 8.2 0.4 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD_2 PF13831.1 EAQ91325.1 - 3.2 7.1 13.2 0.74 9.1 0.0 3.2 3 0 0 3 3 3 0 PHD-finger PUF PF00806.14 EAQ91327.1 - 2.7e-28 95.8 0.0 9e-05 21.7 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EAQ91327.1 - 6.2e-14 51.3 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ91327.1 - 6e-08 32.4 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ91327.1 - 4.5e-06 26.5 0.0 9.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2306 PF10067.4 EAQ91328.1 - 0.0057 16.7 0.1 0.0066 16.5 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Pkinase PF00069.20 EAQ91329.1 - 1.4e-48 165.3 0.0 1.7e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91329.1 - 3.8e-33 114.6 0.0 4.6e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ91329.1 - 1.7e-07 30.5 0.0 1.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ91329.1 - 0.00042 20.1 0.0 0.00057 19.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAQ91329.1 - 0.0034 16.2 0.1 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EAQ91329.1 - 0.082 11.9 0.1 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.4 EAQ91329.1 - 0.47 9.8 6.6 2.1 7.7 4.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein tRNA-synt_2b PF00587.20 EAQ91331.1 - 9.6e-69 230.3 0.1 1.5e-68 229.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAQ91331.1 - 5.4e-23 80.7 0.8 1.4e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Brix PF04427.13 EAQ91332.1 - 2e-34 118.9 0.0 3.1e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain AMPKBI PF04739.10 EAQ91332.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Nop14 PF04147.7 EAQ91332.1 - 0.34 8.7 19.2 0.44 8.4 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family Epimerase PF01370.16 EAQ91335.1 - 6e-49 166.5 0.0 1.5e-48 165.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ91335.1 - 9.5e-21 73.8 0.1 6.8e-20 71.0 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EAQ91335.1 - 6.7e-20 70.9 0.0 9.1e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EAQ91335.1 - 5.2e-19 68.2 0.0 5.3e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EAQ91335.1 - 3.8e-16 58.8 0.0 2.6e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EAQ91335.1 - 8.1e-08 32.4 0.0 1.6e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EAQ91335.1 - 0.0006 19.7 0.0 0.066 13.1 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EAQ91336.1 - 1e-12 48.0 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91336.1 - 2.5e-07 31.0 0.0 6.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91336.1 - 2e-06 28.3 0.1 0.00011 22.7 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91336.1 - 4.8e-06 26.2 0.0 1.6e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91336.1 - 1.4e-05 25.5 0.0 3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAQ91336.1 - 0.00037 20.5 0.0 0.0092 15.9 0.0 2.2 1 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EAQ91336.1 - 0.00066 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EAQ91336.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EAQ91336.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EAQ91336.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EAQ91336.1 - 0.11 11.6 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Pep3_Vps18 PF05131.9 EAQ91337.1 - 6.4e-50 168.4 0.0 2.1e-49 166.7 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EAQ91337.1 - 1.2e-11 44.4 2.6 2.8e-07 30.2 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EAQ91337.1 - 0.001 18.8 1.0 0.0022 17.7 0.7 1.5 1 0 0 1 1 1 1 Ring finger domain DNA_pol3_theta PF06440.6 EAQ91337.1 - 0.0011 18.4 0.0 0.003 17.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, theta subunit zf-RING_5 PF14634.1 EAQ91337.1 - 0.0033 17.1 1.1 0.0063 16.2 0.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_21 PF09976.4 EAQ91337.1 - 0.034 14.0 0.6 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2175 PF09943.4 EAQ91337.1 - 0.096 12.7 0.1 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.2 EAQ91337.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Vps39_2 PF10367.4 EAQ91337.1 - 0.14 12.3 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EAQ91337.1 - 0.25 11.3 1.4 0.77 9.8 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAQ91337.1 - 3 7.5 4.7 0.61 9.7 0.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Asp PF00026.18 EAQ91338.1 - 3.8e-62 210.3 0.0 4.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ91338.1 - 5.8e-11 42.6 0.1 4.5e-10 39.7 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ91338.1 - 2e-08 34.5 1.0 0.0011 19.4 0.2 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EAQ91338.1 - 0.0015 18.0 0.0 0.0037 16.8 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EAQ91338.1 - 0.049 13.4 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease NmrA PF05368.8 EAQ91339.1 - 2.6e-11 43.2 0.0 1.7e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ91339.1 - 9.3e-09 35.5 0.9 1.1e-08 35.2 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EAQ91339.1 - 1.7e-05 24.0 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EAQ91339.1 - 0.0025 17.2 0.1 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 EAQ91339.1 - 0.003 18.0 0.1 0.0054 17.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.5 EAQ91339.1 - 0.023 14.3 0.3 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EAQ91339.1 - 0.094 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-BED PF02892.10 EAQ91340.1 - 0.00018 21.1 0.4 0.00049 19.7 0.3 1.8 1 0 0 1 1 1 1 BED zinc finger DUF4174 PF13778.1 EAQ91340.1 - 0.049 13.7 0.1 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) DUF1660 PF07874.6 EAQ91340.1 - 0.069 13.4 0.8 2.4 8.5 0.1 2.7 2 0 0 2 2 2 0 Prophage protein (DUF1660) WD40 PF00400.27 EAQ91341.1 - 1.7e-29 100.5 8.0 9.1e-09 34.8 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Rrn6 PF10214.4 EAQ91341.1 - 0.025 12.7 0.1 0.038 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIIC_delta PF12657.2 EAQ91341.1 - 0.034 13.8 0.3 2.2 7.9 0.0 2.5 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PQQ_3 PF13570.1 EAQ91341.1 - 0.18 12.1 4.1 10 6.5 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain PUF PF00806.14 EAQ91342.1 - 9.4e-53 172.8 0.6 2.1e-08 33.1 0.0 7.4 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat HypD PF01924.11 EAQ91342.1 - 0.04 12.6 0.1 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family 7tm_7 PF08395.7 EAQ91343.1 - 0.017 14.1 0.2 0.02 13.9 0.1 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Herpes_gE PF02480.11 EAQ91343.1 - 0.025 12.8 0.1 0.045 12.0 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E LMF1 PF06762.9 EAQ91343.1 - 0.12 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor DUF3377 PF11857.3 EAQ91343.1 - 0.19 11.3 2.1 0.36 10.4 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) Phosphodiest PF01663.17 EAQ91344.1 - 6.4e-15 55.3 0.1 1.3e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAQ91344.1 - 0.00014 21.1 0.0 0.00025 20.3 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EAQ91344.1 - 0.00037 19.9 1.2 0.00061 19.2 0.8 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Meth_synt_2 PF01717.13 EAQ91346.1 - 1e-139 465.0 0.0 1.9e-134 447.7 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EAQ91346.1 - 7.5e-113 376.8 0.0 1.1e-101 340.2 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EAQ91346.1 - 0.017 14.0 0.0 5.3 5.8 0.0 2.6 3 0 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) EF-hand_4 PF12763.2 EAQ91347.1 - 4.3e-25 87.4 0.0 1.5e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EAQ91347.1 - 0.00015 21.7 0.1 0.32 11.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair DUF1720 PF08226.6 EAQ91347.1 - 0.00016 21.6 25.8 0.00016 21.6 17.9 6.3 4 2 2 6 6 6 2 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 EAQ91347.1 - 0.00019 21.0 0.1 0.68 9.9 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EAQ91347.1 - 0.00043 19.3 0.0 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 EF hand Fork_head PF00250.13 EAQ91348.1 - 3.4e-34 116.7 0.3 6.8e-34 115.7 0.2 1.4 1 0 0 1 1 1 1 Fork head domain DUF1649 PF07855.7 EAQ91349.1 - 2.4e-67 225.6 0.0 2.9e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) ABA_WDS PF02496.11 EAQ91349.1 - 0.064 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 ABA/WDS induced protein Peroxin-3 PF04882.7 EAQ91350.1 - 1.1e-143 479.0 0.0 1.3e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 TauD PF02668.11 EAQ91351.1 - 0.00089 18.9 1.4 0.42 10.2 0.0 2.3 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Sybindin PF04099.7 EAQ91352.1 - 2.1e-23 82.6 0.0 2.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EAQ91352.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.20 EAQ91353.1 - 4.8e-53 179.9 0.0 6.8e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91353.1 - 4.5e-34 117.6 0.0 6.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ91353.1 - 1.4e-08 34.1 0.0 1.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAQ91353.1 - 4.9e-05 23.1 0.7 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAQ91355.1 - 1.1e-50 172.2 0.0 1.3e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91355.1 - 2.1e-25 89.2 0.0 2.8e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAQ91355.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAQ91355.1 - 0.019 13.9 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EAQ91355.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RNA_pol_L_2 PF13656.1 EAQ91358.1 - 4.4e-30 102.9 0.0 6.3e-30 102.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EAQ91358.1 - 3.6e-11 42.0 0.0 4.9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LAT PF15234.1 EAQ91358.1 - 0.056 12.9 1.0 0.077 12.4 0.7 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Complex1_LYR PF05347.10 EAQ91359.1 - 0.097 12.4 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ91359.1 - 0.11 12.6 0.3 0.24 11.6 0.1 1.7 1 1 1 2 2 2 0 Complex1_LYR-like G10 PF01125.12 EAQ91360.1 - 1.9e-61 205.8 2.5 2.2e-61 205.6 1.7 1.0 1 0 0 1 1 1 1 G10 protein Herpes_pp85 PF04637.7 EAQ91361.1 - 0.014 13.7 0.1 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-C2H2_6 PF13912.1 EAQ91361.1 - 0.068 13.0 2.5 5.2 7.1 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EAQ91361.1 - 1.5 9.3 11.2 4.7 7.7 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 EAQ91361.1 - 3.2 6.1 4.9 4.9 5.5 0.6 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.21 EAQ91361.1 - 4.5 7.8 12.4 3.4 8.1 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type EST1_DNA_bind PF10373.4 EAQ91362.1 - 1.6e-52 178.4 0.0 3.1e-52 177.5 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EAQ91362.1 - 1.2e-26 93.2 0.2 2.4e-26 92.2 0.2 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 PfkB PF00294.19 EAQ91363.1 - 1.3e-64 218.2 0.0 1.5e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EAQ91363.1 - 0.00024 20.4 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Hydrolase_like2 PF13246.1 EAQ91363.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Lyase_1 PF00206.15 EAQ91364.1 - 2.2e-85 286.5 0.0 3e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EAQ91364.1 - 2.7e-26 91.4 0.1 5.2e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal GvpG PF05120.7 EAQ91364.1 - 0.055 13.2 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Gas vesicle protein G SHOCT PF09851.4 EAQ91364.1 - 0.11 11.9 0.4 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 Short C-terminal domain Ribosomal_L2_C PF03947.13 EAQ91365.1 - 3.6e-18 65.6 2.6 4.3e-18 65.3 1.8 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain WHIM1 PF15612.1 EAQ91366.1 - 0.0018 18.1 0.0 0.0048 16.7 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.5 EAQ91367.1 - 1.1e-34 118.9 0.6 1.4e-34 118.7 0.4 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) eRF1_2 PF03464.10 EAQ91368.1 - 7.3e-46 155.7 0.1 1.4e-45 154.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EAQ91368.1 - 5.9e-41 139.2 0.7 1.2e-40 138.2 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EAQ91368.1 - 2.6e-28 98.2 0.0 4.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Flavodoxin_NdrI PF07972.6 EAQ91368.1 - 0.064 13.1 0.5 0.59 10.0 0.1 2.6 2 1 0 2 2 2 0 NrdI Flavodoxin like PDT PF00800.13 EAQ91369.1 - 3.7e-19 68.9 0.0 4.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase MaoC_dehydratas PF01575.14 EAQ91371.1 - 0.033 13.5 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 MaoC like domain LRR_4 PF12799.2 EAQ91372.1 - 0.00044 19.8 5.2 0.93 9.1 0.1 5.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAQ91372.1 - 0.0023 17.7 9.2 12 6.2 0.0 7.0 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.1 EAQ91372.1 - 0.032 13.9 6.8 0.69 9.7 0.0 4.0 5 0 0 5 5 5 0 Leucine rich repeat Pkinase PF00069.20 EAQ91374.1 - 1.6e-68 230.6 0.0 2.6e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91374.1 - 6.2e-50 169.6 0.0 1e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EAQ91374.1 - 2.6e-30 104.4 0.0 7.9e-30 102.8 0.0 1.9 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EAQ91374.1 - 7.6e-16 57.7 0.1 4.7e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAQ91374.1 - 1.3e-14 54.0 0.0 2.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EAQ91374.1 - 3.7e-13 49.7 0.0 6.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EAQ91374.1 - 3.2e-08 32.8 0.0 4.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 EAQ91374.1 - 0.056 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF605 PF04652.11 EAQ91375.1 - 0.081 12.3 28.4 0.11 11.8 19.7 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EAQ91375.1 - 1.5 7.0 15.0 1.8 6.6 10.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EAQ91375.1 - 2.2 8.0 13.1 3 7.6 9.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.14 EAQ91375.1 - 3.2 8.0 21.7 16 5.7 14.8 2.5 1 1 0 1 1 1 0 Dehydrin DUF164 PF02591.10 EAQ91376.1 - 0.036 13.8 0.2 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain Ank_2 PF12796.2 EAQ91377.1 - 1.6e-191 621.2 56.7 3e-23 81.9 0.3 10.5 1 1 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ91377.1 - 3.4e-160 512.5 63.9 6.5e-07 28.8 0.1 22.6 22 0 0 22 22 22 22 Ankyrin repeat Ank_4 PF13637.1 EAQ91377.1 - 3.5e-104 339.5 37.2 5.6e-08 33.0 0.0 21.2 1 1 19 21 21 21 21 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ91377.1 - 4.5e-94 306.3 47.1 6.6e-08 32.5 0.1 19.7 1 1 20 21 21 21 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91377.1 - 7.4e-66 211.4 39.4 0.022 14.9 0.0 22.5 22 0 0 22 22 22 19 Ankyrin repeat RVT_1 PF00078.22 EAQ91377.1 - 1.5e-11 44.0 0.0 7.6e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNP_UDP_1 PF01048.15 EAQ91377.1 - 1.9e-08 33.5 0.1 5.4e-08 32.0 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Exo_endo_phos_2 PF14529.1 EAQ91377.1 - 3.2e-07 29.9 0.0 9.9e-07 28.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ91377.1 - 7.4e-06 26.0 0.0 3.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NACHT PF05729.7 EAQ91377.1 - 0.00065 19.4 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain K_oxygenase PF13434.1 EAQ91379.1 - 0.00084 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EAQ91379.1 - 0.00089 19.0 0.6 0.0027 17.4 0.4 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAQ91379.1 - 0.0049 16.9 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ91379.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EAQ91379.1 - 0.013 15.4 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ91379.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAQ91379.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EAQ91379.1 - 0.045 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EAQ91379.1 - 0.12 10.8 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Zip PF02535.17 EAQ91380.1 - 4.4e-24 85.0 37.9 1.5e-09 37.3 5.0 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter Menin PF05053.8 EAQ91381.1 - 0.0066 14.6 0.9 0.0078 14.4 0.7 1.0 1 0 0 1 1 1 1 Menin Zip PF02535.17 EAQ91383.1 - 9.8e-13 47.7 11.2 4.4e-07 29.2 0.6 2.6 2 1 1 3 3 3 2 ZIP Zinc transporter Sas10 PF09368.5 EAQ91384.1 - 4.3e-30 103.7 7.2 4.3e-30 103.7 5.0 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EAQ91384.1 - 1.7e-14 53.7 0.4 6e-13 48.8 0.0 3.1 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.20 EAQ91385.1 - 1.3e-19 70.7 0.1 1.3e-19 70.7 0.1 2.7 4 0 0 4 4 4 1 short chain dehydrogenase DUF3716 PF12511.3 EAQ91385.1 - 6.3e-16 57.7 8.3 1.1e-15 57.0 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) KR PF08659.5 EAQ91385.1 - 2.7e-07 30.4 0.1 1.1e-06 28.4 0.1 2.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ91385.1 - 1.2e-05 25.0 0.1 3.3e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EAQ91385.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ91385.1 - 0.017 15.1 2.1 0.045 13.7 0.8 2.3 2 1 0 2 2 2 0 NADH(P)-binding DUF4129 PF13559.1 EAQ91385.1 - 1.2 9.1 7.2 6 6.9 2.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4129) SelP_N PF04592.9 EAQ91385.1 - 1.4 8.2 19.9 0.66 9.3 6.3 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region G-alpha PF00503.15 EAQ91386.1 - 6.3e-133 443.2 1.4 7.7e-133 442.9 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAQ91386.1 - 1.9e-15 56.5 1.3 3e-10 39.5 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EAQ91386.1 - 0.0002 20.8 0.0 0.00087 18.7 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EAQ91386.1 - 0.00051 20.5 0.1 0.76 10.2 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EAQ91386.1 - 0.0035 16.4 3.4 0.21 10.6 0.0 2.6 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EAQ91386.1 - 0.0059 16.1 0.1 0.032 13.7 0.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain MCM PF00493.18 EAQ91386.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family GTP_EFTU PF00009.22 EAQ91386.1 - 0.046 13.1 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAQ91386.1 - 0.063 13.2 0.0 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EAQ91386.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1771 PF08590.5 EAQ91387.1 - 2e-21 75.7 8.6 2e-21 75.7 6.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EAQ91387.1 - 1.2e-15 57.4 0.2 1.2e-15 57.4 0.2 2.1 2 0 0 2 2 2 1 Smr domain DUF1597 PF07642.6 EAQ91388.1 - 0.023 13.7 0.3 0.03 13.3 0.2 1.0 1 0 0 1 1 1 0 Outer membrane protein family (DUF1597) DUF543 PF04418.7 EAQ91389.1 - 1e-29 102.2 0.0 1.1e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2456 PF10445.4 EAQ91389.1 - 0.034 14.0 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) FTR1 PF03239.9 EAQ91389.1 - 0.049 12.5 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Urb2 PF10441.4 EAQ91390.1 - 4.1e-69 232.6 0.0 1.2e-68 231.0 0.0 1.9 1 0 0 1 1 1 1 Urb2/Npa2 family ERAP1_C PF11838.3 EAQ91390.1 - 0.0017 17.6 0.7 0.0017 17.6 0.5 2.2 2 1 0 2 2 2 1 ERAP1-like C-terminal domain D123 PF07065.9 EAQ91391.1 - 1.2e-75 254.3 0.0 1.4e-64 218.0 0.0 3.3 2 2 0 2 2 2 2 D123 HCMV_UL139 PF12507.3 EAQ91391.1 - 0.051 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein cwf21 PF08312.7 EAQ91392.1 - 3e-16 58.9 16.3 3e-16 58.9 11.3 1.9 2 0 0 2 2 2 1 cwf21 domain RasGEF PF00617.14 EAQ91393.1 - 4.3e-59 199.4 0.0 1.2e-58 197.9 0.0 1.8 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAQ91393.1 - 3.9e-26 91.1 0.6 1e-25 89.8 0.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EAQ91393.1 - 5.9e-16 57.5 0.1 1.3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAQ91393.1 - 9e-14 50.7 0.2 1.8e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAQ91393.1 - 3.8e-13 48.7 0.1 8.7e-13 47.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EAQ91393.1 - 2.2e-05 24.2 0.0 4.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 WW domain zf-H2C2_2 PF13465.1 EAQ91395.1 - 1.9e-08 34.1 12.5 1.6e-05 24.9 4.1 3.1 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.13 EAQ91395.1 - 2.4e-08 33.1 0.9 2.4e-06 26.6 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EAQ91395.1 - 4.9e-05 23.3 13.0 0.0038 17.4 3.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ91395.1 - 0.00021 21.4 14.7 0.033 14.5 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_16 PF00722.16 EAQ91396.1 - 4.8e-13 48.8 0.0 8.5e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HEAT_2 PF13646.1 EAQ91397.1 - 1.2e-06 28.7 1.5 0.00096 19.3 0.1 5.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EAQ91397.1 - 0.0002 21.1 12.1 1.9 8.7 0.0 6.9 9 0 0 9 9 9 2 HEAT repeat DUF165 PF02592.10 EAQ91397.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 HEAT_EZ PF13513.1 EAQ91397.1 - 0.12 12.9 6.8 4.7 7.8 0.0 5.6 5 0 0 5 5 5 0 HEAT-like repeat RVT_1 PF00078.22 EAQ91398.1 - 3.3e-32 111.5 0.0 4.5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Homeobox PF00046.24 EAQ91399.1 - 0.006 16.1 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAQ91399.1 - 0.0099 15.5 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Rhodanese PF00581.15 EAQ91402.1 - 1.1e-08 35.3 0.0 3.5e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C14 PF00656.17 EAQ91402.1 - 0.00075 19.2 0.0 0.02 14.5 0.0 2.2 1 1 1 2 2 2 1 Caspase domain DUF4372 PF14294.1 EAQ91402.1 - 0.025 14.4 0.1 0.081 12.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) PIG-X PF08320.7 EAQ91403.1 - 2.1e-35 121.8 0.0 3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Sulfotransfer_3 PF13469.1 EAQ91404.1 - 4.4e-05 24.4 0.0 0.00011 23.2 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family Mhr1 PF12829.2 EAQ91405.1 - 1.2e-30 105.1 0.0 1.8e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.9 EAQ91406.1 - 1.9e-47 161.3 0.0 1e-45 155.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EAQ91406.1 - 1.4e-27 96.4 0.0 4.6e-15 55.9 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EAQ91406.1 - 4.7e-22 77.6 0.8 4.7e-22 77.6 0.6 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EAQ91406.1 - 2.3e-16 59.7 0.0 1.8e-10 40.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ91406.1 - 1.3e-15 57.8 15.3 5.8e-06 26.4 0.0 6.6 3 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 EAQ91406.1 - 5.4e-14 52.4 0.0 2.7e-05 24.3 0.0 4.1 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EAQ91406.1 - 4.4e-09 36.0 0.0 1.3e-05 24.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EAQ91406.1 - 3.4e-08 34.3 5.0 0.0089 16.8 0.0 3.8 2 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EAQ91406.1 - 1.5e-07 31.3 0.0 0.013 15.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EAQ91406.1 - 1.7e-07 31.5 0.1 0.01 16.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EAQ91406.1 - 3.6e-07 29.8 1.4 0.035 13.8 0.1 3.6 3 0 0 3 3 3 2 Part of AAA domain Clp_N PF02861.15 EAQ91406.1 - 7.5e-07 28.9 2.4 0.0011 18.8 0.0 4.0 3 0 0 3 3 3 1 Clp amino terminal domain IstB_IS21 PF01695.12 EAQ91406.1 - 7.7e-07 28.6 0.0 0.023 14.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EAQ91406.1 - 1.1e-06 28.5 6.2 0.0059 16.3 0.4 5.0 4 2 0 4 4 4 1 Archaeal ATPase Mg_chelatase PF01078.16 EAQ91406.1 - 7.1e-06 25.3 0.1 0.14 11.3 0.0 3.5 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EAQ91406.1 - 2.5e-05 24.1 0.0 0.22 11.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EAQ91406.1 - 3e-05 24.0 0.3 0.27 11.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EAQ91406.1 - 4.7e-05 23.5 0.0 0.42 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EAQ91406.1 - 0.00014 21.5 0.0 0.88 9.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EAQ91406.1 - 0.00018 21.0 0.0 0.98 9.0 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAQ91406.1 - 0.00022 20.6 1.2 1.4 8.2 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EAQ91406.1 - 0.00023 20.6 4.5 0.039 13.4 0.0 4.7 5 1 0 5 5 5 1 AAA-like domain T2SE PF00437.15 EAQ91406.1 - 0.00025 20.0 2.2 0.024 13.5 0.1 3.0 3 1 0 3 3 3 1 Type II/IV secretion system protein ResIII PF04851.10 EAQ91406.1 - 0.00045 20.1 0.0 0.24 11.2 0.0 3.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EAQ91406.1 - 0.00045 20.5 0.4 0.52 10.6 0.0 3.2 3 0 0 3 3 2 1 ABC transporter DUF258 PF03193.11 EAQ91406.1 - 0.00079 18.6 0.0 0.36 10.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EAQ91406.1 - 0.00088 18.7 0.0 0.83 9.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 EAQ91406.1 - 0.0017 18.1 0.0 0.17 11.5 0.0 3.4 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 EAQ91406.1 - 0.0019 17.8 0.0 0.19 11.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 EAQ91406.1 - 0.0027 17.3 0.0 2.1 7.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain Torsin PF06309.6 EAQ91406.1 - 0.0055 16.5 0.0 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 Torsin SRP54 PF00448.17 EAQ91406.1 - 0.016 14.6 0.0 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EAQ91406.1 - 0.021 14.7 0.2 1.9 8.3 0.0 2.9 4 0 0 4 4 2 0 AAA domain UPF0079 PF02367.12 EAQ91406.1 - 0.028 14.0 0.0 8.1 6.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EAQ91406.1 - 0.065 12.7 0.0 8.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EAQ91406.1 - 0.092 12.2 0.0 6.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Snapin_Pallidin PF14712.1 EAQ91406.1 - 0.23 11.7 6.1 2.4 8.5 1.4 2.9 2 0 0 2 2 2 0 Snapin/Pallidin Peptidase_M16 PF00675.15 EAQ91406.1 - 0.28 10.9 1.3 8 6.2 0.0 2.5 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) IncA PF04156.9 EAQ91406.1 - 1.2 8.7 7.2 3.2 7.2 5.0 1.8 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EAQ91406.1 - 1.2 6.8 2.5 1.9 6.2 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EAQ91406.1 - 1.8 8.8 0.0 1.8 8.8 0.0 4.1 3 1 0 3 3 2 0 AAA domain Macoilin PF09726.4 EAQ91406.1 - 6.1 5.0 9.7 9.8 4.3 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein PrpF PF04303.8 EAQ91407.1 - 2.5e-51 174.5 0.1 2.1e-48 164.9 0.1 2.1 1 1 1 2 2 2 2 PrpF protein DsbD_2 PF13386.1 EAQ91408.1 - 0.015 15.0 0.2 0.024 14.3 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Fungal_trans_2 PF11951.3 EAQ91408.1 - 0.022 13.3 0.1 0.03 12.9 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_1 PF00515.23 EAQ91409.1 - 2.3e-36 121.9 22.5 5.6e-05 22.5 0.1 12.7 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91409.1 - 1.7e-31 105.5 34.4 0.0015 18.2 0.1 13.4 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ91409.1 - 2.8e-31 104.9 22.5 2.2e-05 23.9 0.1 12.4 12 1 0 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ91409.1 - 3.8e-29 100.1 41.3 2.6e-07 30.1 1.1 11.8 5 3 7 14 14 14 8 TPR repeat TPR_12 PF13424.1 EAQ91409.1 - 1.1e-22 79.7 33.6 3.7e-07 29.9 0.3 9.9 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ91409.1 - 1.6e-19 69.9 37.7 5.1e-06 26.7 0.4 11.3 9 4 4 14 14 13 7 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ91409.1 - 3.1e-16 57.8 39.8 0.00019 20.9 0.1 12.2 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ91409.1 - 4.1e-14 52.8 54.1 2.2e-05 24.9 0.0 11.7 9 3 2 12 12 11 6 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ91409.1 - 1.8e-13 49.9 25.0 0.00083 19.6 0.0 10.8 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ91409.1 - 4.6e-12 45.4 51.9 0.0019 18.6 0.0 13.4 11 6 6 17 17 14 6 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ91409.1 - 1.5e-10 40.4 18.8 1.1 9.6 0.2 11.0 11 0 0 11 11 11 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ91409.1 - 6.1e-08 32.6 19.5 0.024 14.7 0.8 7.5 6 2 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EAQ91409.1 - 0.39 10.7 0.0 0.39 10.7 0.0 8.8 12 1 0 12 12 9 0 Tetratricopeptide repeat TPR_3 PF07720.7 EAQ91409.1 - 4.5 7.1 9.6 51 3.8 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat PX PF00787.19 EAQ91411.1 - 3.8e-19 68.5 0.0 8.9e-18 64.1 0.0 2.7 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 EAQ91411.1 - 2.4e-08 33.5 0.6 2.4e-08 33.5 0.4 1.9 2 0 0 2 2 2 1 Vps5 C terminal like Ndc1_Nup PF09531.5 EAQ91411.1 - 4.6 5.5 5.9 9.3 4.5 4.1 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup mRNA_cap_enzyme PF01331.14 EAQ91412.1 - 4.2e-52 176.6 0.1 5.6e-52 176.2 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EAQ91412.1 - 9.2e-21 74.1 0.0 2.5e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EAQ91412.1 - 1.6e-07 30.8 0.3 5.4e-06 25.9 0.2 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain 2OG-FeII_Oxy PF03171.15 EAQ91413.1 - 0.065 13.5 0.0 0.29 11.4 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EAQ91414.1 - 3.7e-10 39.1 0.4 6.5e-10 38.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Borrelia_lipo_1 PF05714.6 EAQ91414.1 - 0.33 10.0 0.0 0.53 9.3 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein FAD_binding_6 PF00970.19 EAQ91415.1 - 1.6e-26 92.2 0.0 2.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EAQ91415.1 - 2.4e-21 76.3 0.0 5e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EAQ91415.1 - 0.00034 20.5 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EAQ91415.1 - 0.00093 19.1 0.0 0.0086 16.0 0.0 2.1 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DUF788 PF05620.6 EAQ91416.1 - 7.1e-46 156.1 0.0 7.8e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF2955 PF11168.3 EAQ91416.1 - 0.00064 19.4 0.6 0.37 10.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2955) FA_desaturase PF00487.19 EAQ91416.1 - 0.48 9.8 7.2 0.93 8.8 5.0 1.4 1 1 0 1 1 1 0 Fatty acid desaturase TPR_11 PF13414.1 EAQ91417.1 - 5.1e-33 112.5 21.6 7.9e-14 51.0 2.2 7.4 5 3 2 7 7 7 4 TPR repeat Apc3 PF12895.2 EAQ91417.1 - 4.6e-31 106.7 14.5 6.9e-21 74.1 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EAQ91417.1 - 8.1e-30 101.1 17.2 7.1e-08 31.7 0.7 8.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91417.1 - 4.4e-29 98.0 17.5 1.1e-06 28.0 0.4 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ91417.1 - 5.4e-23 80.7 18.0 7.7e-10 38.5 0.2 7.2 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ91417.1 - 1.8e-19 68.0 5.1 4.5e-06 26.0 0.3 7.8 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ91417.1 - 2.3e-19 69.4 11.5 3.2e-07 30.5 1.1 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ91417.1 - 2.7e-19 67.8 12.2 0.0044 17.5 0.0 9.3 5 1 5 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ91417.1 - 9.2e-18 62.9 11.7 0.0012 18.8 0.2 8.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ91417.1 - 9.9e-18 64.3 30.2 3.6e-08 33.8 1.0 8.0 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ91417.1 - 1e-13 49.9 9.4 0.00021 20.8 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ91417.1 - 3.1e-11 42.9 8.7 0.012 16.0 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ91417.1 - 6.3e-05 22.7 6.7 0.19 11.6 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAQ91417.1 - 9e-05 22.2 9.2 7.2 6.5 0.1 5.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 EAQ91417.1 - 0.00029 19.9 7.5 0.029 13.4 0.1 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ91417.1 - 0.0077 16.1 11.5 1.7 8.7 0.0 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ91417.1 - 0.011 16.1 2.5 35 5.2 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat FAT PF02259.18 EAQ91417.1 - 0.027 13.4 0.1 0.049 12.6 0.1 1.3 1 0 0 1 1 1 0 FAT domain DUF2225 PF09986.4 EAQ91417.1 - 0.033 13.6 0.2 2 7.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 EAQ91417.1 - 1.4 8.8 7.1 12 5.8 1.3 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Sedlin_N PF04628.8 EAQ91418.1 - 7.1e-14 51.7 0.0 8.2e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MobC PF05713.6 EAQ91418.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) L31 PF09784.4 EAQ91419.1 - 2.1e-48 162.6 1.9 2.3e-48 162.5 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 PRT_C PF08372.5 EAQ91419.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Val_tRNA-synt_C PF10458.4 EAQ91419.1 - 0.14 12.2 0.7 4.5 7.4 0.2 2.6 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF2951 PF11166.3 EAQ91419.1 - 0.15 11.9 0.2 0.18 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RRM_1 PF00076.17 EAQ91420.1 - 8.9e-12 44.4 0.0 1.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ91420.1 - 1.9e-09 37.3 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ91420.1 - 5.9e-09 35.6 0.1 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 EAQ91421.1 - 0.006 14.5 2.0 0.41 8.4 0.0 3.4 3 1 1 4 4 4 2 Nuclear pore component FliT PF05400.8 EAQ91421.1 - 0.19 12.1 10.2 0.66 10.4 1.2 2.8 2 0 0 2 2 2 0 Flagellar protein FliT PAT1 PF09770.4 EAQ91422.1 - 9.3 4.3 24.2 13 3.8 16.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MGC-24 PF05283.6 EAQ91423.1 - 5.6 6.7 6.0 6 6.6 4.2 1.0 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) PI3_PI4_kinase PF00454.22 EAQ91424.1 - 3.7e-27 95.3 0.0 6.5e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EAQ91424.1 - 6.2e-20 70.6 0.4 1.3e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Cep57_MT_bd PF06657.8 EAQ91424.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 AA_permease_2 PF13520.1 EAQ91425.1 - 2.1e-47 161.6 25.1 1.2e-27 96.5 8.4 2.1 1 1 1 2 2 2 2 Amino acid permease DUF3392 PF11872.3 EAQ91425.1 - 0.7 9.8 7.1 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) CBFD_NFYB_HMF PF00808.18 EAQ91427.1 - 2.5e-13 49.8 1.3 4.7e-13 48.9 0.9 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAQ91427.1 - 2.1e-05 24.5 0.4 4.5e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4643 PF15485.1 EAQ91427.1 - 0.32 10.4 5.1 0.36 10.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Abhydrolase_3 PF07859.8 EAQ91429.1 - 3.2e-19 69.3 0.0 4.2e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAQ91429.1 - 3.4e-15 55.5 0.0 4.1e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) FGGY_C PF02782.11 EAQ91430.1 - 1.3e-27 96.7 0.0 2.6e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAQ91430.1 - 3.4e-16 59.2 0.0 3.9e-07 29.6 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Sad1_UNC PF07738.8 EAQ91431.1 - 2.5e-36 124.4 0.0 4.3e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Muskelin_N PF06588.6 EAQ91431.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Muskelin N-terminus RRM_2 PF04059.7 EAQ91432.1 - 1.5e-13 50.5 0.0 2.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Sec15 PF04091.7 EAQ91433.1 - 6.3e-101 337.7 2.9 1.8e-100 336.2 2.0 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 EAQ91433.1 - 0.00094 18.6 1.6 0.00094 18.6 1.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) DUF3510 PF12022.3 EAQ91433.1 - 0.0012 18.8 2.0 1.2 9.2 0.0 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF3510) CBFD_NFYB_HMF PF00808.18 EAQ91434.1 - 1.6e-19 69.6 0.6 2.8e-19 68.9 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAQ91434.1 - 2e-11 43.8 0.1 4.2e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EAQ91434.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X tRNA-synt_1b PF00579.20 EAQ91435.1 - 1.3e-57 195.1 0.3 6.2e-30 104.3 0.0 2.5 2 1 1 3 3 3 2 tRNA synthetases class I (W and Y) Fcf2 PF08698.6 EAQ91435.1 - 9.7e-27 92.8 0.1 3.6e-26 91.0 0.0 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.17 EAQ91435.1 - 3.5e-23 81.2 0.0 8.2e-23 80.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Peptidase_M24 PF00557.19 EAQ91437.1 - 1.9e-40 138.6 0.0 2.7e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EAQ91437.1 - 7.8e-23 81.4 0.0 5.9e-18 65.6 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain LemA PF04011.7 EAQ91439.1 - 0.038 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 LemA family TBCA PF02970.11 EAQ91439.1 - 1.1 9.3 7.9 6.3 6.9 0.5 2.6 2 0 0 2 2 2 0 Tubulin binding cofactor A TIP41 PF04176.8 EAQ91440.1 - 2.4e-70 235.4 0.0 3e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EAQ91441.1 - 5.5e-70 235.4 0.0 6.7e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91441.1 - 1e-42 146.0 0.0 1.3e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ91441.1 - 1.1e-07 31.1 0.0 3.5e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAQ91441.1 - 0.0027 16.8 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ91441.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAQ91441.1 - 0.04 13.2 0.1 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Peptidase_M76 PF09768.4 EAQ91442.1 - 7.3e-34 116.7 1.0 2.6e-26 92.1 0.7 2.1 1 1 1 2 2 2 2 Peptidase M76 family AA_kinase PF00696.23 EAQ91443.1 - 5.4e-35 121.0 0.4 5.4e-35 121.0 0.3 1.8 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 EAQ91443.1 - 1.1e-13 50.7 12.7 2.3e-13 49.6 6.9 2.6 2 1 0 2 2 2 1 PUA domain DUF2633 PF11119.3 EAQ91443.1 - 0.31 10.7 2.8 0.65 9.7 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) UPF0113 PF03657.8 EAQ91444.1 - 2.5e-06 27.2 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EAQ91444.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain GMC_oxred_C PF05199.8 EAQ91445.1 - 1.1e-24 87.3 0.5 1.9e-24 86.5 0.4 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAQ91445.1 - 4.2e-24 85.2 0.0 1.1e-23 83.8 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 EAQ91445.1 - 5.3e-11 41.9 10.4 1.2e-10 40.8 7.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 EAQ91445.1 - 1.7e-10 40.3 1.1 0.00017 20.6 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAQ91445.1 - 6.3e-07 28.6 0.7 0.0002 20.3 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EAQ91445.1 - 9.3e-05 21.6 0.2 0.021 13.9 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ91445.1 - 0.0001 22.4 0.2 0.049 13.6 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 EAQ91445.1 - 0.00027 20.8 0.0 0.00094 19.1 0.0 1.9 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.9 EAQ91445.1 - 0.00089 17.8 0.2 0.0015 17.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EAQ91445.1 - 0.0009 19.1 0.2 0.0023 17.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ91445.1 - 0.0011 18.9 0.4 0.0031 17.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAQ91445.1 - 0.0015 17.6 0.1 0.0038 16.3 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EAQ91445.1 - 0.01 16.2 0.3 0.2 12.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ91445.1 - 0.026 13.5 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EAQ91445.1 - 0.16 10.8 0.6 0.3 9.9 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.19 EAQ91446.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EAQ91446.1 - 0.007 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAQ91446.1 - 0.11 12.3 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EAQ91447.1 - 9.5e-61 204.0 0.3 1.1e-60 203.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAQ91447.1 - 5.4e-09 35.2 0.7 0.00057 18.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EAQ91447.1 - 9.3e-08 31.6 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EAQ91447.1 - 1.5e-07 31.3 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ91447.1 - 4.2e-07 30.4 0.0 6.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EAQ91447.1 - 1.6e-05 24.1 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAQ91447.1 - 2.7e-05 23.4 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EAQ91447.1 - 7.5e-05 22.2 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAQ91447.1 - 0.032 14.0 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EAQ91447.1 - 0.036 13.5 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EAQ91447.1 - 0.042 14.6 0.3 0.074 13.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ91447.1 - 0.055 13.1 0.0 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PPK2 PF03976.9 EAQ91447.1 - 0.15 11.3 0.1 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) DUF4045 PF13254.1 EAQ91448.1 - 6.4e-75 252.9 35.5 3.2e-44 151.8 17.3 5.3 4 2 1 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EAQ91448.1 - 5e-07 29.3 0.0 0.0064 16.1 0.0 3.3 3 0 0 3 3 3 2 Gelsolin repeat Med10 PF09748.4 EAQ91449.1 - 2.3e-48 163.2 0.2 2.6e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2408 PF10303.4 EAQ91449.1 - 0.14 12.3 0.1 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Methyltransf_23 PF13489.1 EAQ91451.1 - 5.9e-31 107.3 0.0 8.1e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91451.1 - 0.00031 20.3 0.0 0.058 12.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91451.1 - 0.0016 18.9 0.1 0.032 14.8 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91451.1 - 0.12 12.8 0.0 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain bZIP_1 PF00170.16 EAQ91452.1 - 2.4e-05 24.1 8.4 5.1e-05 23.1 5.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EAQ91452.1 - 0.18 11.4 0.4 0.31 10.5 0.3 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GvpL_GvpF PF06386.6 EAQ91452.1 - 0.43 10.1 4.4 0.65 9.5 3.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 EAQ91452.1 - 0.69 9.7 8.5 1.5 8.7 5.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF4407 PF14362.1 EAQ91452.1 - 1.7 7.5 4.6 2.5 6.9 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EAQ91453.1 - 1.9e-15 57.3 0.3 1.9e-15 57.3 0.2 4.4 3 1 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EAQ91453.1 - 1.2e-07 32.1 11.9 1.2e-07 32.1 8.3 2.4 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family MFS_1 PF07690.11 EAQ91454.1 - 2.8e-17 62.4 32.6 5.2e-09 35.2 6.3 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ91454.1 - 0.038 13.7 1.4 1.3 8.9 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family 7tm_7 PF08395.7 EAQ91454.1 - 0.39 9.6 3.6 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF3272 PF11676.3 EAQ91454.1 - 2.8 8.0 4.4 11 6.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3272) Mtc PF03820.12 EAQ91455.1 - 7.7e-94 313.7 0.1 6.2e-65 218.8 0.2 2.0 2 0 0 2 2 2 2 Tricarboxylate carrier Pkinase PF00069.20 EAQ91456.1 - 5.5e-49 166.6 0.0 8.2e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ91456.1 - 2.4e-11 43.2 0.0 2e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Lactamase_B_2 PF12706.2 EAQ91458.1 - 2.2e-32 112.1 0.0 3.5e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EAQ91458.1 - 3.5e-25 87.2 0.0 7.4e-25 86.2 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EAQ91458.1 - 6.9e-09 35.6 0.0 1.9e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DEAD PF00270.24 EAQ91459.1 - 9.4e-44 148.8 0.1 9.4e-44 148.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2183 PF09949.4 EAQ91459.1 - 3.3e-32 110.4 0.0 9e-32 108.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.26 EAQ91459.1 - 4.3e-17 61.7 0.0 1.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LNS2 PF08235.8 EAQ91459.1 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Glyoxalase PF00903.20 EAQ91459.1 - 0.06 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1253 PF06862.7 EAQ91459.1 - 0.17 10.2 0.2 8.4 4.6 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1253) Serglycin PF04360.7 EAQ91460.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Serglycin Glyco_hydro_16 PF00722.16 EAQ91461.1 - 1.9e-07 30.5 0.0 3.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Flavin_Reduct PF01613.13 EAQ91462.1 - 1.2e-16 60.9 0.0 1.8e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.10 EAQ91463.1 - 1.3e-46 159.1 0.0 2.8e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EAQ91463.1 - 0.00022 20.8 0.0 0.00057 19.4 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAQ91463.1 - 0.0094 15.6 0.5 0.041 13.5 0.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pol_alpha_B_N PF08418.5 EAQ91464.1 - 0.33 10.4 5.3 0.68 9.4 3.2 1.9 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-C2H2_2 PF12756.2 EAQ91465.1 - 2.1e-24 85.5 11.8 1.2e-22 79.8 4.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EAQ91465.1 - 0.012 15.7 6.1 0.057 13.5 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.23 EAQ91466.1 - 1.5e-57 194.9 2.7 3.2e-21 75.2 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EAQ91466.1 - 4.6e-10 40.0 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EAQ91466.1 - 0.031 14.0 0.4 0.077 12.8 0.3 1.6 1 0 0 1 1 1 0 Gas vesicle protein G SNARE PF05739.14 EAQ91469.1 - 1.2e-07 31.2 2.3 2.1e-07 30.5 1.6 1.4 1 0 0 1 1 1 1 SNARE domain PX PF00787.19 EAQ91469.1 - 3.6e-07 29.9 0.1 6.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Drf_FH1 PF06346.7 EAQ91469.1 - 0.14 11.6 4.8 0.23 10.9 3.3 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 F-box-like PF12937.2 EAQ91473.1 - 0.0014 18.2 0.0 0.0052 16.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ91473.1 - 0.019 14.6 0.1 0.069 12.8 0.1 1.9 1 0 0 1 1 1 0 F-box domain Pectate_lyase PF03211.8 EAQ91474.1 - 2.7e-71 239.3 3.5 3.4e-71 239.0 2.4 1.0 1 0 0 1 1 1 1 Pectate lyase DUF1996 PF09362.5 EAQ91475.1 - 1e-80 270.7 2.9 1.2e-80 270.5 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) EB1 PF03271.12 EAQ91476.1 - 2.6e-18 65.7 0.4 5.9e-18 64.6 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EAQ91476.1 - 1.4e-06 28.2 0.9 2.8e-06 27.3 0.6 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Phi-29_GP3 PF05435.6 EAQ91476.1 - 0.078 12.1 0.4 0.11 11.6 0.0 1.4 2 0 0 2 2 2 0 Phi-29 DNA terminal protein GP3 Glyco_transf_8 PF01501.15 EAQ91477.1 - 0.00052 19.4 0.0 0.004 16.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Flavokinase PF01687.12 EAQ91479.1 - 1.7e-08 34.3 0.0 3.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Glyco_hydro_61 PF03443.9 EAQ91480.1 - 4.7e-60 203.1 0.1 8.6e-60 202.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAQ91480.1 - 1.4e-08 34.1 15.4 1.4e-08 34.1 10.7 3.7 2 2 0 2 2 2 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 EAQ91480.1 - 0.0077 16.2 0.1 0.2 11.7 0.0 2.9 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Serglycin PF04360.7 EAQ91481.1 - 1.6 8.4 9.0 3.1 7.5 0.4 2.3 2 0 0 2 2 2 0 Serglycin Man-6-P_recep PF02157.10 EAQ91482.1 - 1e-11 44.3 0.0 1.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EAQ91482.1 - 6.4e-08 32.4 0.1 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EAQ91482.1 - 5.7e-06 25.7 18.8 2.4e-05 23.6 10.4 3.3 1 1 1 2 2 2 1 Autophagy-related protein 27 PPP4R2 PF09184.6 EAQ91482.1 - 0.00095 18.8 13.0 0.0015 18.1 9.0 1.2 1 0 0 1 1 1 1 PPP4R2 PTRF_SDPR PF15237.1 EAQ91482.1 - 0.057 12.8 3.5 0.085 12.2 2.4 1.2 1 0 0 1 1 1 0 PTRF/SDPR family CDC45 PF02724.9 EAQ91482.1 - 0.25 9.3 15.0 0.33 8.9 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EAQ91482.1 - 0.26 9.7 14.3 0.34 9.3 9.9 1.1 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 EAQ91482.1 - 1.4 7.0 3.7 1.7 6.8 2.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NOA36 PF06524.7 EAQ91482.1 - 1.6 7.9 12.4 2.5 7.2 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EAQ91482.1 - 3.2 5.5 23.0 0.069 11.0 10.7 1.7 2 0 0 2 2 2 0 Nop14-like family ERG4_ERG24 PF01222.12 EAQ91483.1 - 1.4e-172 574.1 1.1 1.6e-172 573.9 0.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EAQ91483.1 - 1.2e-05 24.7 0.2 3.7e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) LSM PF01423.17 EAQ91484.1 - 1.9e-11 43.3 0.0 2.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain ExbD PF02472.11 EAQ91485.1 - 0.1 12.5 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Glyco_hydro_3 PF00933.16 EAQ91486.1 - 6.9e-93 310.8 0.1 1.5e-92 309.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ91486.1 - 3.8e-59 199.9 0.8 1.9e-58 197.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ91486.1 - 1.7e-15 56.6 0.0 4.1e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1823 PF08853.6 EAQ91486.1 - 0.021 14.5 0.0 7.7 6.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1823) Abhydrolase_6 PF12697.2 EAQ91489.1 - 6.5e-08 32.7 0.1 7.5e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ91489.1 - 2e-07 30.8 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EAQ91489.1 - 1.4e-06 27.7 0.0 2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAQ91489.1 - 7.1e-06 25.8 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EAQ91489.1 - 0.00018 21.0 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase LCAT PF02450.10 EAQ91489.1 - 0.0045 16.0 0.0 0.0059 15.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Cutinase PF01083.17 EAQ91489.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EAQ91489.1 - 0.02 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 EAQ91489.1 - 0.058 12.5 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2305 PF10230.4 EAQ91489.1 - 0.059 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EAQ91490.1 - 2.9e-07 30.6 0.1 5.2e-07 29.7 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EAQ91490.1 - 0.00057 19.2 0.0 0.0013 18.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAQ91490.1 - 0.0071 16.0 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ91490.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein NACHT PF05729.7 EAQ91491.1 - 1.1e-12 47.9 0.1 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ91491.1 - 4.3e-08 33.3 0.2 8.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ91491.1 - 9.4e-07 29.0 0.0 3.3e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAQ91491.1 - 8.3e-05 22.7 0.0 0.00026 21.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Abhydrolase_6 PF12697.2 EAQ91491.1 - 9.7e-05 22.3 0.0 0.00029 20.7 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_5 PF07728.9 EAQ91491.1 - 0.0019 17.8 0.1 0.059 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EAQ91491.1 - 0.0021 17.5 0.0 0.0065 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Abhydrolase_5 PF12695.2 EAQ91491.1 - 0.0033 17.2 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_tran PF00005.22 EAQ91491.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 EAQ91491.1 - 0.006 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EAQ91491.1 - 0.0069 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAQ91491.1 - 0.0074 17.0 0.0 0.027 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAQ91491.1 - 0.0092 15.6 0.3 0.038 13.6 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EAQ91491.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF676 PF05057.9 EAQ91491.1 - 0.022 14.0 0.0 0.093 12.0 0.0 2.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) IstB_IS21 PF01695.12 EAQ91491.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EAQ91491.1 - 0.078 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAQ91491.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MIS13 PF08202.6 EAQ91492.1 - 0.014 14.4 1.0 0.018 14.1 0.7 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Reo_sigmaC PF04582.7 EAQ91492.1 - 0.024 13.8 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1732 PF08340.6 EAQ91492.1 - 0.049 13.4 0.8 0.079 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) IRF-2BP1_2 PF11261.3 EAQ91492.1 - 0.097 12.1 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Lzipper-MIP1 PF14389.1 EAQ91492.1 - 0.12 12.5 6.7 0.99 9.5 0.9 3.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ADIP PF11559.3 EAQ91492.1 - 0.12 12.3 3.0 0.33 10.8 0.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EAQ91492.1 - 0.16 11.7 5.0 0.28 11.0 3.4 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phasin PF05597.6 EAQ91492.1 - 0.19 11.4 2.1 0.43 10.3 0.2 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tropomyosin_1 PF12718.2 EAQ91492.1 - 0.35 10.7 5.3 1.9 8.3 3.7 1.9 1 1 0 1 1 1 0 Tropomyosin like TMF_TATA_bd PF12325.3 EAQ91492.1 - 0.39 10.4 4.1 0.66 9.7 0.9 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EAQ91492.1 - 0.41 11.0 2.1 1.6 9.0 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF1192 PF06698.6 EAQ91492.1 - 0.41 10.4 2.5 12 5.7 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) UPF0242 PF06785.6 EAQ91492.1 - 0.49 9.0 2.3 0.65 8.6 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF2051 PF09738.4 EAQ91492.1 - 0.58 9.3 4.7 0.27 10.4 0.1 2.0 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Prefoldin_2 PF01920.15 EAQ91492.1 - 0.93 9.2 4.5 11 5.8 0.1 2.6 2 1 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EAQ91492.1 - 1.2 8.7 8.2 12 5.4 0.6 3.1 2 1 1 3 3 3 0 Septum formation initiator GrpE PF01025.14 EAQ91493.1 - 0.011 15.3 0.9 0.013 15.0 0.6 1.1 1 0 0 1 1 1 0 GrpE AMP-binding PF00501.23 EAQ91494.1 - 1.3e-75 254.3 0.0 1.7e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ91494.1 - 0.00012 22.9 0.2 0.00068 20.5 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_3 PF00202.16 EAQ91495.1 - 1.4e-10 40.5 0.0 2.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EAQ91495.1 - 0.017 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Glyoxalase_2 PF12681.2 EAQ91495.1 - 0.02 15.4 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain SnoaL PF07366.7 EAQ91496.1 - 3.7e-05 23.3 0.1 0.00021 20.8 0.1 2.0 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EAQ91496.1 - 0.0003 21.1 0.1 0.00094 19.5 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain PIP5K PF01504.13 EAQ91498.1 - 5.4e-34 117.4 0.0 9.2e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PALP PF00291.20 EAQ91499.1 - 1.1e-61 208.7 0.2 1.5e-61 208.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EAQ91499.1 - 3.5e-07 29.9 0.0 2e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 CBS domain SRPRB PF09439.5 EAQ91500.1 - 2.5e-24 85.4 0.0 1.7e-15 56.6 0.0 3.2 2 1 1 3 3 3 3 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAQ91500.1 - 1.7e-05 24.7 0.0 4.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EAQ91500.1 - 0.0002 20.6 0.0 0.028 13.6 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 EAQ91500.1 - 0.00043 20.3 0.9 0.0011 19.0 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EAQ91500.1 - 0.0054 17.0 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EAQ91500.1 - 0.006 15.7 0.2 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAQ91500.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EAQ91500.1 - 0.014 15.6 0.0 2.5 8.3 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EAQ91500.1 - 0.038 13.4 0.1 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EAQ91500.1 - 0.048 13.0 0.0 1.3 8.4 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EAQ91500.1 - 0.051 13.0 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EAQ91500.1 - 0.15 12.5 0.0 3.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Miro-like protein Ras PF00071.17 EAQ91500.1 - 0.17 11.2 0.0 0.78 9.1 0.0 2.1 2 1 0 2 2 2 0 Ras family DGF-1_4 PF11024.3 EAQ91500.1 - 1.2 9.5 14.2 0.31 11.4 0.5 2.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 zf-DHHC PF01529.15 EAQ91501.1 - 2.5e-36 124.7 7.0 2.5e-36 124.7 4.8 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 EAQ91501.1 - 1.6e-35 119.1 1.1 8.3e-08 31.6 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 EAQ91501.1 - 2.1e-33 114.5 0.0 1.5e-16 60.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ91501.1 - 4.4e-27 93.4 1.2 2.8e-07 30.5 0.0 6.1 2 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91501.1 - 1.4e-22 77.5 1.3 9.8e-07 28.4 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EAQ91501.1 - 3.4e-22 78.3 2.5 3.6e-07 30.5 0.3 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) DLH PF01738.13 EAQ91502.1 - 1.7e-30 105.9 0.4 2.4e-30 105.4 0.3 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAQ91502.1 - 1e-05 25.2 0.3 1.6e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ91502.1 - 0.054 12.7 0.1 0.93 8.6 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family NmrA PF05368.8 EAQ91504.1 - 5.7e-27 94.4 0.0 7.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ91504.1 - 2.5e-16 60.2 0.0 3.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ91504.1 - 0.18 11.2 0.1 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RVT_1 PF00078.22 EAQ91505.1 - 3.1e-18 65.9 0.0 7.9e-18 64.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ91505.1 - 2.2e-15 56.3 0.0 6.1e-14 51.6 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ91505.1 - 4.2e-05 23.5 0.1 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EAQ91505.1 - 0.0082 16.0 2.4 0.0082 16.0 1.6 3.0 4 0 0 4 4 4 1 Zinc knuckle Peptidase_M56 PF05569.6 EAQ91505.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 zf-CCCH PF00642.19 EAQ91507.1 - 0.003 17.1 9.8 0.029 14.0 1.2 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Acyl_transf_3 PF01757.17 EAQ91509.1 - 2e-37 128.8 36.2 2.6e-37 128.4 25.1 1.1 1 0 0 1 1 1 1 Acyltransferase family UDPG_MGDP_dh_N PF03721.9 EAQ91513.1 - 4.8e-40 136.9 0.2 3.5e-34 117.8 0.1 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EAQ91513.1 - 4.3e-25 87.7 0.0 8.8e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EAQ91513.1 - 4.1e-23 81.5 0.1 1.9e-17 63.3 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EAQ91513.1 - 0.0033 17.1 0.3 0.019 14.7 0.2 2.3 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_tranf_2_3 PF13641.1 EAQ91514.1 - 2.1e-30 106.2 0.6 3e-30 105.7 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAQ91514.1 - 6e-21 74.8 0.0 9.2e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EAQ91514.1 - 2.7e-19 69.6 3.4 5.7e-19 68.5 0.4 2.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EAQ91514.1 - 3.8e-19 68.6 0.0 6e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_12 PF01670.11 EAQ91514.1 - 9e-10 38.5 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Cellulose_synt PF03552.9 EAQ91514.1 - 0.00013 20.5 0.1 0.015 13.6 0.0 2.3 2 0 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 EAQ91514.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_hydro_7 PF00840.15 EAQ91517.1 - 5.7e-130 433.5 18.7 1.9e-128 428.5 13.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 Fer4_20 PF14691.1 EAQ91517.1 - 0.09 12.4 2.8 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster ATG16 PF08614.6 EAQ91518.1 - 0.0068 16.2 13.1 0.0068 16.2 9.1 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF2562 PF10814.3 EAQ91518.1 - 0.14 12.1 8.9 0.15 12.0 0.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2562) YedD PF13987.1 EAQ91518.1 - 0.15 11.6 2.2 0.23 11.0 0.3 2.1 1 1 1 2 2 2 0 YedD-like protein Strep_SA_rep PF06696.6 EAQ91518.1 - 0.44 10.3 11.5 0.85 9.4 0.9 3.8 3 0 0 3 3 3 0 Streptococcal surface antigen repeat TFIIA PF03153.8 EAQ91518.1 - 0.93 9.3 15.9 1.2 8.9 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.10 EAQ91518.1 - 2.7 7.5 25.8 1 8.8 1.8 3.8 1 1 2 3 3 3 0 Septum formation initiator Spectrin PF00435.16 EAQ91518.1 - 4.4 7.6 20.4 28 5.0 8.1 2.6 1 1 1 2 2 2 0 Spectrin repeat OmdA PF13376.1 EAQ91519.1 - 1.7e-22 78.8 0.1 4.7e-22 77.4 0.1 1.8 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Zn_clus PF00172.13 EAQ91519.1 - 4.2e-07 29.7 5.1 1.1e-06 28.4 3.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 EAQ91520.1 - 1.3e-14 54.5 0.0 1.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tyrosinase PF00264.15 EAQ91521.1 - 5.4e-40 137.9 4.4 7.1e-40 137.5 3.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase rve PF00665.21 EAQ91522.1 - 1.7e-12 47.4 0.0 5.6e-11 42.5 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.9 EAQ91522.1 - 3.3e-07 29.5 0.0 6.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EAQ91522.1 - 1.2e-05 24.8 0.4 3.4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain An_peroxidase PF03098.10 EAQ91524.1 - 6e-91 305.4 0.0 7.9e-60 202.7 0.0 2.0 1 1 1 2 2 2 2 Animal haem peroxidase DPPIV_N PF00930.16 EAQ91525.1 - 1.7e-105 352.4 4.1 3.1e-105 351.6 2.2 1.9 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EAQ91525.1 - 4.7e-37 127.2 1.2 7.9e-37 126.5 0.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ91525.1 - 2.5e-05 24.0 0.1 0.00013 21.7 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EAQ91525.1 - 0.00029 20.3 1.1 0.00029 20.3 0.7 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) HTH_29 PF13551.1 EAQ91526.1 - 0.0011 19.1 0.2 0.0017 18.5 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix MFS_1 PF07690.11 EAQ91529.1 - 7.1e-29 100.6 26.1 1e-20 73.8 7.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ91529.1 - 3.9e-08 32.3 6.9 3.9e-08 32.3 4.8 2.3 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EAQ91529.1 - 0.0078 15.9 0.8 0.025 14.3 0.3 2.1 2 0 0 2 2 2 1 MFS_1 like family UNC-93 PF05978.11 EAQ91529.1 - 0.015 14.8 0.6 0.015 14.8 0.4 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 RE_Alw26IDE PF09665.5 EAQ91531.1 - 0.13 10.9 0.2 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) zf-CHY PF05495.7 EAQ91533.1 - 0.0074 16.4 1.4 0.013 15.5 1.0 1.4 1 0 0 1 1 1 1 CHY zinc finger Med15 PF09606.5 EAQ91534.1 - 0.38 8.8 14.7 0.52 8.4 10.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EAQ91534.1 - 2.1 8.1 6.6 2.6 7.8 4.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YppG PF14179.1 EAQ91534.1 - 3.9 8.1 12.8 6.1 7.4 8.9 1.3 1 0 0 1 1 1 0 YppG-like protein PAT1 PF09770.4 EAQ91534.1 - 4.6 5.3 11.1 5.5 5.1 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4106 PF13388.1 EAQ91534.1 - 5.4 5.8 13.3 7 5.5 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PC4 PF02229.11 EAQ91535.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) A2L_zn_ribbon PF08792.5 EAQ91535.1 - 0.019 14.4 0.8 0.027 13.9 0.5 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain DNA_ligase_A_C PF04679.10 EAQ91535.1 - 0.078 13.3 0.0 0.092 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Glyco_transf_25 PF01755.12 EAQ91536.1 - 8.4e-11 41.8 0.0 5.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Herpes_gE PF02480.11 EAQ91537.1 - 0.012 13.9 0.0 0.016 13.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EAQ91537.1 - 0.025 13.9 0.7 0.06 12.6 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 EAQ91537.1 - 0.065 11.8 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.1 EAQ91537.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1996 PF09362.5 EAQ91538.1 - 7.8e-89 297.3 0.4 9.8e-89 297.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAQ91538.1 - 0.0038 16.8 8.8 0.0038 16.8 6.1 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain AAA_22 PF13401.1 EAQ91539.1 - 0.00031 20.8 0.0 0.0013 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAQ91539.1 - 0.00086 19.3 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EAQ91539.1 - 0.0095 15.5 0.4 0.05 13.2 0.3 2.2 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EAQ91539.1 - 0.017 14.7 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ91539.1 - 0.046 14.5 0.0 0.26 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAQ91539.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EAQ91539.1 - 0.067 12.6 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EAQ91539.1 - 0.11 12.7 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EAQ91539.1 - 0.12 11.8 0.1 0.38 10.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain S1 PF00575.18 EAQ91540.1 - 6.1e-05 23.0 0.1 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain WD40 PF00400.27 EAQ91542.1 - 1.6e-43 145.0 20.7 1.1e-09 37.8 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EAQ91542.1 - 3.2e-08 33.1 0.2 7.8e-08 31.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EAQ91542.1 - 5.3e-07 28.1 4.9 0.19 9.8 0.6 4.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 EAQ91542.1 - 7.3e-07 28.6 0.0 1.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EAQ91542.1 - 4e-05 22.5 1.2 0.12 11.1 0.2 3.3 2 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 EAQ91542.1 - 0.0005 19.6 0.2 0.0016 17.9 0.1 1.8 1 1 1 2 2 2 2 PQQ-like domain Proteasome_A_N PF10584.4 EAQ91542.1 - 0.15 11.4 0.2 14 5.1 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Pectate_lyase_3 PF12708.2 EAQ91543.1 - 1.9e-81 273.4 17.1 2.5e-65 220.7 6.9 3.1 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EAQ91543.1 - 6.1e-06 25.6 2.2 0.04 13.3 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EAQ91543.1 - 0.2 11.3 14.2 0.11 12.3 7.5 2.3 2 0 0 2 2 2 0 Right handed beta helix region DUF1996 PF09362.5 EAQ91546.1 - 1.1e-88 296.9 2.1 1.4e-88 296.5 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) His_Phos_1 PF00300.17 EAQ91549.1 - 8.2e-17 61.7 0.0 1.3e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MC1 PF05854.6 EAQ91550.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Glyco_hydro_18 PF00704.23 EAQ91551.1 - 9.1e-81 271.9 0.8 1.3e-80 271.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EAQ91551.1 - 1.6e-15 56.8 110.5 3.7e-09 36.4 11.0 5.4 5 0 0 5 5 5 4 Chitin recognition protein FSH1 PF03959.8 EAQ91553.1 - 0.014 14.8 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Dmrt1 PF12374.3 EAQ91553.1 - 0.1 12.9 0.4 0.13 12.6 0.3 1.2 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Lipase_GDSL_2 PF13472.1 EAQ91555.1 - 9.6e-18 64.9 1.7 1.2e-17 64.6 1.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ91555.1 - 7.7e-12 45.5 3.2 1.3e-11 44.8 2.2 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.23 EAQ91556.1 - 4.5e-144 479.8 3.1 1.5e-72 244.2 0.0 3.2 2 1 1 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EAQ91556.1 - 4.8e-53 179.9 0.0 2.5e-24 85.6 0.0 3.7 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EAQ91556.1 - 2.9e-19 69.0 0.1 3.7e-11 43.1 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ91556.1 - 8.4e-16 58.6 1.4 3.7e-07 31.0 0.0 3.3 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EAQ91557.1 - 1e-19 70.4 72.0 1.6e-18 66.5 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CMD PF02627.15 EAQ91558.1 - 0.063 13.1 0.0 13 5.7 0.0 2.3 1 1 1 2 2 2 0 Carboxymuconolactone decarboxylase family ADH_zinc_N_2 PF13602.1 EAQ91559.1 - 5.2e-05 24.1 2.2 0.00099 20.0 0.1 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase Amidase PF01425.16 EAQ91560.1 - 1.2e-95 320.9 0.0 1.5e-95 320.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Methyltransf_3 PF01596.12 EAQ91561.1 - 1.3e-26 92.9 0.0 1.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EAQ91561.1 - 2.5e-14 53.9 0.0 5.1e-14 53.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91561.1 - 1.6e-12 47.9 0.0 2.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91561.1 - 4.9e-11 42.4 0.0 7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAQ91561.1 - 3.8e-09 36.3 0.0 4.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EAQ91561.1 - 3e-08 33.6 0.0 4.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91561.1 - 2.3e-05 24.1 0.0 4.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91561.1 - 3.8e-05 24.1 0.0 0.00012 22.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91561.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAQ91561.1 - 0.00028 20.3 0.0 0.00036 19.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EAQ91561.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EAQ91561.1 - 0.0022 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CmcI PF04989.7 EAQ91561.1 - 0.0081 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Spermine_synth PF01564.12 EAQ91561.1 - 0.044 12.7 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 Spermine/spermidine synthase UPF0020 PF01170.13 EAQ91561.1 - 0.099 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ApoLp-III PF07464.6 EAQ91561.1 - 0.17 11.9 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) F-box-like PF12937.2 EAQ91565.1 - 0.0019 17.9 0.3 0.0054 16.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like MULE PF10551.4 EAQ91566.1 - 9.5e-05 22.4 0.1 0.00032 20.8 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain Acyl_transf_3 PF01757.17 EAQ91568.1 - 3.1e-17 62.4 17.8 1.3e-16 60.3 11.9 2.2 1 1 1 2 2 2 1 Acyltransferase family RVT_1 PF00078.22 EAQ91570.1 - 1.8e-18 66.6 0.0 3.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ91570.1 - 1.4e-11 43.8 0.1 1.4e-11 43.8 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EAQ91570.1 - 0.013 14.8 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger WD40 PF00400.27 EAQ91571.1 - 3.7e-57 188.2 21.4 9.7e-10 37.9 0.1 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EAQ91571.1 - 3.6e-09 36.2 0.2 8.4e-09 35.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EAQ91571.1 - 9.1e-09 33.9 3.1 0.033 12.3 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 EAQ91571.1 - 5.6e-07 29.0 0.0 2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain YmzC PF14157.1 EAQ91571.1 - 0.016 15.0 0.0 20 5.1 0.0 3.4 3 0 0 3 3 3 0 YmzC-like protein PQQ_2 PF13360.1 EAQ91571.1 - 0.097 12.1 1.1 4.6 6.6 0.0 2.9 2 1 0 3 3 3 0 PQQ-like domain Mito_carr PF00153.22 EAQ91572.1 - 1.4e-48 162.5 1.2 4.7e-21 74.2 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 EAQ91573.1 - 2.1e-67 227.6 0.0 2.7e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EAQ91574.1 - 1.6e-10 40.6 0.0 2.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain NPV_P10 PF05531.7 EAQ91579.1 - 0.036 14.3 6.3 7.6 6.8 0.1 4.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EAQ91579.1 - 0.099 12.5 2.2 1.4 8.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LrgB PF04172.11 EAQ91580.1 - 2.4e-11 43.1 1.9 7.8e-06 25.2 0.1 2.9 2 1 0 2 2 2 2 LrgB-like family Rotamase PF00639.16 EAQ91581.1 - 1.5e-22 80.1 0.0 2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EAQ91581.1 - 3.9e-16 59.3 0.0 5.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EAQ91581.1 - 3.6e-08 33.1 1.0 8.1e-08 31.9 0.7 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EAQ91581.1 - 2.6e-05 24.8 0.0 3.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain BCL_N PF04714.8 EAQ91581.1 - 0.13 11.8 0.5 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Ribosomal_L14 PF00238.14 EAQ91583.1 - 5.7e-42 142.3 2.7 6.3e-42 142.1 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS_3 PF08447.6 EAQ91583.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 PAS fold SET PF00856.23 EAQ91584.1 - 1.1e-09 38.8 0.0 3.7e-08 33.8 0.0 2.7 2 0 0 2 2 2 1 SET domain Velvet PF11754.3 EAQ91586.1 - 1e-06 28.4 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Wzt_C PF14524.1 EAQ91586.1 - 0.026 14.2 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain Acid_phosphat_B PF03767.9 EAQ91586.1 - 0.033 13.5 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4442 PF14539.1 EAQ91586.1 - 0.04 13.8 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) ACC_central PF08326.7 EAQ91587.1 - 1.3e-238 793.7 0.0 2.5e-206 687.0 0.0 2.1 1 1 1 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 EAQ91587.1 - 9.2e-40 136.1 0.0 5.4e-19 68.3 0.0 2.4 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 EAQ91587.1 - 1.8e-38 132.1 0.0 2.7e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Biotin_carb_C PF02785.14 EAQ91587.1 - 5.4e-22 77.8 0.0 4.5e-19 68.4 0.0 2.9 3 0 0 3 3 3 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EAQ91587.1 - 7.4e-15 54.3 0.1 1.5e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EAQ91587.1 - 1.7e-08 34.3 0.0 3.2e-07 30.2 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EAQ91587.1 - 1.5e-05 23.9 0.0 0.011 14.5 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EAQ91587.1 - 4.5e-05 22.9 0.0 8.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EAQ91587.1 - 0.0018 18.1 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EAQ91587.1 - 0.09 12.4 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like RimK PF08443.6 EAQ91587.1 - 0.15 11.5 0.0 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain NUDE_C PF04880.8 EAQ91588.1 - 8.3e-19 68.5 2.3 8.3e-19 68.5 1.6 4.2 1 1 4 5 5 5 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EAQ91588.1 - 0.0063 16.7 7.8 0.0063 16.7 5.4 3.7 2 1 2 4 4 4 1 Protein of unknown function (DUF904) Chibby PF14645.1 EAQ91588.1 - 0.12 12.2 10.4 0.7 9.7 0.5 2.7 1 1 1 2 2 2 0 Chibby family CENP-F_leu_zip PF10473.4 EAQ91588.1 - 0.23 11.3 32.1 0.064 13.1 14.1 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EAQ91588.1 - 0.25 10.9 32.5 0.44 10.1 13.4 2.7 2 1 1 3 3 3 0 IncA protein WEMBL PF05701.6 EAQ91588.1 - 1.5 7.1 30.0 0.071 11.5 17.0 1.4 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF745 PF05335.8 EAQ91588.1 - 2 7.8 11.5 2 7.9 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Filament PF00038.16 EAQ91588.1 - 2.7 7.3 27.8 20 4.5 17.4 2.6 2 1 0 2 2 2 0 Intermediate filament protein IFT57 PF10498.4 EAQ91588.1 - 6.7 5.3 19.4 0.061 12.0 4.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 RTBV_P46 PF06216.6 EAQ91588.1 - 9.1 4.9 9.6 6.2 5.5 1.0 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein NUDIX PF00293.23 EAQ91589.1 - 1.9e-14 53.4 0.4 5.3e-14 52.0 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain Glyco_hydro_61 PF03443.9 EAQ91590.1 - 1.1e-62 211.6 0.0 1.3e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AA_permease PF00324.16 EAQ91591.1 - 3.3e-83 279.6 41.3 3.3e-68 230.1 18.3 2.2 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAQ91591.1 - 3e-25 88.6 40.5 2.3e-22 79.1 17.3 2.1 1 1 1 2 2 2 2 Amino acid permease Homeobox_KN PF05920.6 EAQ91593.1 - 2.7e-15 55.7 0.2 7.4e-15 54.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EAQ91593.1 - 4.5e-09 35.7 0.2 1e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 EAQ91593.1 - 0.00012 22.1 22.3 0.016 15.5 1.4 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 EAQ91593.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 EAQ91593.1 - 0.0038 17.4 25.9 0.0066 16.6 1.5 4.8 4 1 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EAQ91593.1 - 0.028 14.6 0.9 20 5.5 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAQ91593.1 - 1.5 8.9 4.1 33 4.6 0.1 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EAQ91593.1 - 3.4 8.1 10.2 2.4 8.5 0.3 3.7 4 1 0 4 4 4 0 Zinc-finger double domain TPMT PF05724.6 EAQ91594.1 - 2.8e-30 105.3 0.0 5.1e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EAQ91594.1 - 5.3e-07 30.1 0.0 8.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91594.1 - 1.9e-05 25.0 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ91594.1 - 2.5e-05 24.2 0.1 6.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91594.1 - 2.6e-05 24.0 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91594.1 - 3.7e-05 23.3 0.0 0.00079 19.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PG_binding_3 PF09374.5 EAQ91594.1 - 0.1 12.6 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain N2227 PF07942.7 EAQ91594.1 - 0.26 10.2 0.0 0.45 9.4 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein DUF1308 PF07000.6 EAQ91595.1 - 1.5e-24 86.3 0.0 2.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Cys_Met_Meta_PP PF01053.15 EAQ91595.1 - 3.5e-21 74.9 0.0 4.8e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aft1_HRR PF11787.3 EAQ91596.1 - 3.1 8.8 9.7 0.74 10.9 4.1 1.8 2 0 0 2 2 2 0 Aft1 HRR domain NmrA PF05368.8 EAQ91597.1 - 5.8e-41 140.2 0.0 9.9e-41 139.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ91597.1 - 2.1e-20 73.4 0.0 2.8e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ91597.1 - 3.2e-05 23.4 0.1 0.00011 21.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ91597.1 - 0.00013 20.7 0.0 0.00025 19.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EAQ91597.1 - 0.00077 19.4 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EAQ91597.1 - 0.0066 16.8 0.2 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EAQ91597.1 - 0.016 15.4 0.2 0.09 13.0 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EAQ91597.1 - 0.017 15.0 0.5 0.038 13.8 0.4 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Saccharop_dh PF03435.13 EAQ91597.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HeLo PF14479.1 EAQ91598.1 - 5.7e-40 137.3 0.0 6.7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.2 EAQ91601.1 - 5.8e-21 74.6 2.1 3.1e-11 43.4 0.0 5.4 4 1 2 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ91601.1 - 6.9e-18 63.4 6.1 1.9e-06 27.3 0.0 5.9 6 0 0 6 6 5 3 Ankyrin repeat Ank_5 PF13857.1 EAQ91601.1 - 7.7e-13 48.2 2.7 0.00012 22.2 0.1 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91601.1 - 8.5e-13 47.2 3.8 0.011 15.9 0.0 7.1 8 0 0 8 8 6 3 Ankyrin repeat Ank_4 PF13637.1 EAQ91601.1 - 3.1e-12 46.6 1.1 6e-06 26.6 0.0 5.0 4 1 1 5 5 4 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 EAQ91601.1 - 3.9e-07 30.2 0.5 1.9e-06 27.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ91601.1 - 0.0001 22.4 0.1 0.0028 17.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EAQ91601.1 - 0.00035 20.2 0.0 0.0014 18.3 0.0 2.1 1 1 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EAQ91601.1 - 0.0008 18.4 0.1 0.0019 17.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EAQ91601.1 - 0.0026 17.4 0.0 0.013 15.2 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EAQ91601.1 - 0.079 11.8 0.0 0.47 9.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Dimer_Tnp_hAT PF05699.9 EAQ91602.1 - 0.00011 21.7 0.0 0.00088 18.8 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region PfkB PF00294.19 EAQ91603.1 - 1.2e-11 44.2 0.1 1.7e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase APH PF01636.18 EAQ91604.1 - 1.8e-05 24.6 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RVT_1 PF00078.22 EAQ91605.1 - 1.5e-14 53.9 0.0 8.2e-13 48.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Myb_DNA-bind_6 PF13921.1 EAQ91607.1 - 8.4e-05 22.6 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ91607.1 - 0.0017 18.3 0.2 0.0043 17.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Abhydrolase_6 PF12697.2 EAQ91608.1 - 2e-29 103.1 9.7 2.7e-29 102.6 6.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ91608.1 - 4.2e-10 39.3 0.0 1.3e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EAQ91608.1 - 2.6e-09 36.9 0.4 6e-09 35.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ91608.1 - 6.5e-09 35.6 0.0 0.002 17.6 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAQ91608.1 - 0.035 13.3 0.0 1.4 8.0 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family HSP20 PF00011.16 EAQ91609.1 - 3.2e-17 62.2 0.1 1.8e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family TRAP_alpha PF03896.11 EAQ91609.1 - 0.61 9.0 2.9 0.8 8.6 2.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peroxidase_2 PF01328.12 EAQ91611.1 - 1.2e-30 106.2 0.2 1.7e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.3 EAQ91612.1 - 3.8e-08 32.3 1.2 5.3e-08 31.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHO4 PF01384.15 EAQ91613.1 - 4.8e-79 265.3 14.5 6.3e-79 264.9 10.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family Metallophos PF00149.23 EAQ91614.1 - 0.00023 20.6 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAQ91614.1 - 0.027 14.3 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Lipase_GDSL_2 PF13472.1 EAQ91615.1 - 3e-09 37.2 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Homeobox_KN PF05920.6 EAQ91615.1 - 0.002 17.7 0.0 0.048 13.3 0.0 2.7 2 1 0 2 2 2 1 Homeobox KN domain Swi3 PF07962.7 EAQ91615.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Nop25 PF09805.4 EAQ91616.1 - 0.053 13.5 11.0 0.11 12.5 7.7 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) Sod_Fe_N PF00081.17 EAQ91616.1 - 0.062 13.5 0.2 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain MAT1 PF06391.8 EAQ91616.1 - 0.09 12.3 5.8 0.13 11.8 4.0 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 BTV_NS2 PF04514.7 EAQ91616.1 - 0.25 10.1 8.5 0.34 9.7 5.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 EAQ91616.1 - 9.7 6.5 10.7 12 6.2 2.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cu-oxidase_3 PF07732.10 EAQ91617.1 - 2.5e-38 130.4 11.2 4.3e-38 129.6 2.6 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAQ91617.1 - 8.1e-38 129.0 12.4 2.9e-37 127.2 0.8 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EAQ91617.1 - 1.5e-32 112.7 0.0 4.5e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase 3Beta_HSD PF01073.14 EAQ91618.1 - 1.3e-10 40.4 0.0 3.7e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ91618.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ91618.1 - 1.4e-09 37.2 0.0 7.6e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EAQ91618.1 - 8.9e-07 29.0 0.1 5.4e-06 26.5 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ91618.1 - 0.00053 19.3 0.0 0.00073 18.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAQ91618.1 - 0.0098 15.8 0.8 0.081 12.8 0.4 2.6 2 1 0 2 2 2 1 short chain dehydrogenase DUF2079 PF09852.4 EAQ91619.1 - 0.036 12.7 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) LysM PF01476.15 EAQ91620.1 - 8.5e-27 92.7 1.5 0.0002 21.2 0.0 6.4 6 0 0 6 6 6 6 LysM domain DUF1153 PF06627.6 EAQ91620.1 - 0.041 13.7 0.0 76 3.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1153) Como_LCP PF02247.11 EAQ91620.1 - 6.3 5.0 9.3 9.4 4.5 0.2 3.4 4 0 0 4 4 4 0 Large coat protein Lipase_GDSL_2 PF13472.1 EAQ91621.1 - 1.9e-11 44.3 0.2 1.7e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ91621.1 - 6.5e-06 26.1 1.1 4.1e-05 23.5 0.8 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_1 PF05184.10 EAQ91621.1 - 0.075 12.8 0.9 0.15 11.9 0.6 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 Reprolysin_2 PF13574.1 EAQ91622.1 - 0.00055 20.0 0.5 0.0011 19.0 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAQ91622.1 - 0.00076 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.19 EAQ91622.1 - 0.0027 17.1 0.7 0.06 12.7 0.3 2.6 3 0 0 3 3 3 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 EAQ91622.1 - 0.0056 16.2 1.5 0.016 14.7 0.8 1.9 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAQ91622.1 - 0.012 16.1 0.1 0.036 14.5 0.0 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAQ91622.1 - 0.014 15.0 0.5 0.035 13.8 0.3 1.8 2 1 0 2 2 2 0 Matrixin Peptidase_M66 PF10462.4 EAQ91622.1 - 0.072 11.9 0.8 0.11 11.3 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Glyco_hydro_18 PF00704.23 EAQ91623.1 - 2.6e-70 237.5 0.0 3.4e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EAQ91623.1 - 3.9e-06 26.7 8.9 3.9e-06 26.7 6.2 2.8 2 1 0 2 2 2 2 Chitin recognition protein Glyco_hydro_85 PF03644.8 EAQ91623.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 RVT_2 PF07727.9 EAQ91626.1 - 1.9e-11 43.4 0.0 3.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91626.1 - 7.3e-09 35.7 0.0 2.3e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ91626.1 - 1.2e-05 24.8 0.4 3e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Catalase PF00199.14 EAQ91629.1 - 5.4e-160 532.2 0.2 6.8e-160 531.9 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EAQ91629.1 - 2.9e-23 81.4 0.1 5.8e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EAQ91629.1 - 1.2e-09 37.8 0.1 2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.1 EAQ91630.1 - 0.00015 21.6 1.1 0.0017 18.2 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Ketoacyl-synt_C PF02801.17 EAQ91630.1 - 0.066 13.0 0.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Laminin_B PF00052.13 EAQ91630.1 - 0.13 11.8 0.2 0.35 10.4 0.1 1.7 2 0 0 2 2 2 0 Laminin B (Domain IV) DUF164 PF02591.10 EAQ91631.1 - 0.06 13.1 0.7 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain Tht1 PF04163.7 EAQ91634.1 - 0.00035 19.0 2.0 0.0011 17.4 0.4 2.0 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein DUF1308 PF07000.6 EAQ91634.1 - 0.038 12.6 0.8 0.054 12.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Glyco_tranf_2_3 PF13641.1 EAQ91635.1 - 7.2e-06 25.9 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 SNF2_N PF00176.18 EAQ91637.1 - 6.7e-12 44.8 0.0 9.1e-06 24.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ91637.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ91637.1 - 0.0039 17.0 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Dimer_Tnp_hAT PF05699.9 EAQ91638.1 - 0.0002 20.9 0.0 0.00055 19.5 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cyclin_N PF00134.18 EAQ91639.1 - 1.3e-28 99.0 0.1 2.1e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Reo_sigmaC PF04582.7 EAQ91640.1 - 0.00037 19.7 0.1 0.00058 19.1 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EAQ91640.1 - 0.0047 16.0 4.3 0.0047 16.0 3.0 1.9 2 0 0 2 2 2 1 Tropomyosin Snapin_Pallidin PF14712.1 EAQ91640.1 - 0.14 12.4 1.9 0.23 11.8 0.2 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Lzipper-MIP1 PF14389.1 EAQ91640.1 - 0.44 10.6 5.8 8.1 6.6 0.2 3.6 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 TBPIP PF07106.8 EAQ91640.1 - 3.9 6.9 5.9 0.42 10.1 1.1 1.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EAQ91640.1 - 5.3 6.9 6.5 3.1 7.6 1.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EAQ91640.1 - 9.9 5.9 12.2 0.2 11.4 1.0 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding MULE PF10551.4 EAQ91641.1 - 1.4e-08 34.7 3.7 1.7e-06 28.1 0.1 2.9 1 1 1 2 2 2 2 MULE transposase domain FAR1 PF03101.10 EAQ91641.1 - 0.0041 17.5 0.3 0.012 16.1 0.2 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF2992 PF11208.3 EAQ91641.1 - 0.029 14.2 1.4 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) RVT_1 PF00078.22 EAQ91642.1 - 2e-20 73.0 0.0 4.9e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91642.1 - 3.9e-15 56.0 0.1 7.3e-14 51.9 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ91642.1 - 5.7e-06 25.9 2.0 1.2e-05 24.9 1.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Exo_endo_phos_2 PF14529.1 EAQ91643.1 - 4.6e-22 77.8 0.1 2.4e-20 72.3 0.0 3.5 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EAQ91643.1 - 3.8e-16 59.0 0.0 8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EAQ91643.1 - 9.4e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ91643.1 - 0.011 16.0 4.6 0.17 12.2 2.4 2.8 1 1 1 2 2 2 0 SlyX CorA PF01544.13 EAQ91643.1 - 0.1 11.5 2.2 0.21 10.5 1.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ91643.1 - 0.29 11.2 5.6 0.098 12.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Mnd1 PF03962.10 EAQ91643.1 - 0.36 10.4 2.4 0.85 9.2 1.7 1.6 1 0 0 1 1 1 0 Mnd1 family FAR1 PF03101.10 EAQ91644.1 - 0.0024 18.3 0.4 0.0036 17.8 0.2 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Cellulase PF00150.13 EAQ91644.1 - 0.033 13.3 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) KTI12 PF08433.5 EAQ91644.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HMG_box PF00505.14 EAQ91645.1 - 1.4e-22 79.6 0.3 5.3e-22 77.8 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ91645.1 - 5.5e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain SNF2_N PF00176.18 EAQ91647.1 - 2.4e-15 56.1 0.0 1.1e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ91647.1 - 0.0029 17.4 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ91647.1 - 0.008 16.0 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Dynamin_N PF00350.18 EAQ91648.1 - 3.8e-08 33.3 0.0 6.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Pkinase PF00069.20 EAQ91649.1 - 4.9e-11 42.2 0.0 7.9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF1494 PF07379.6 EAQ91649.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1494) DUF1282 PF06930.7 EAQ91649.1 - 0.039 13.6 0.5 0.082 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2189 PF09955.4 EAQ91649.1 - 0.081 12.8 2.6 0.18 11.7 1.6 1.7 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF3325 PF11804.3 EAQ91650.1 - 2 8.4 17.4 0.38 10.7 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) Helicase_C PF00271.26 EAQ91651.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SSP160 PF06933.6 EAQ91652.1 - 0.091 10.7 5.4 0.12 10.3 3.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Alpha_GJ PF03229.8 EAQ91652.1 - 8.7 6.6 12.3 0.24 11.7 3.9 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J Abhydrolase_5 PF12695.2 EAQ91653.1 - 4.9e-05 23.1 0.1 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAQ91653.1 - 9.4e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAQ91653.1 - 0.0011 18.8 0.1 0.0013 18.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EAQ91653.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase DLH PF01738.13 EAQ91653.1 - 0.023 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF829 PF05705.9 EAQ91653.1 - 0.026 14.2 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_2 PF02230.11 EAQ91653.1 - 0.11 11.9 0.1 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.21 EAQ91654.1 - 9.3e-61 205.5 0.3 3.4e-60 203.6 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAQ91654.1 - 1.4e-11 44.2 0.1 2.8e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EAQ91654.1 - 3.8e-07 29.3 0.2 4.8e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EAQ91654.1 - 0.0029 17.2 0.1 0.0069 16.0 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.17 EAQ91655.1 - 4.1e-18 65.1 0.0 7.6e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 VQ PF05678.9 EAQ91656.1 - 0.12 11.4 0.0 0.12 11.4 0.0 2.3 3 0 0 3 3 3 0 VQ motif COesterase PF00135.23 EAQ91657.1 - 3.6e-97 326.3 0.0 6.8e-97 325.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ91657.1 - 3.3e-05 23.5 8.4 0.013 15.0 0.2 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold SQS_PSY PF00494.14 EAQ91657.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase Fungal_trans PF04082.13 EAQ91658.1 - 1.2e-05 24.3 1.0 2.9e-05 23.0 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ91658.1 - 7.7e-05 22.5 7.1 0.00015 21.6 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EAQ91659.1 - 1.2e-21 76.8 48.7 1.9e-21 76.1 33.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily VWA_3 PF13768.1 EAQ91660.1 - 0.041 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain TPR_14 PF13428.1 EAQ91660.1 - 0.042 14.4 0.2 5 8.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EAQ91661.1 - 5e-31 107.6 32.1 5e-31 107.6 22.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SET PF00856.23 EAQ91663.1 - 6.9e-06 26.4 0.0 9.6e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 SET domain F-box-like PF12937.2 EAQ91664.1 - 0.0049 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Peptidase_M24 PF00557.19 EAQ91665.1 - 3.3e-46 157.4 0.1 4.7e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EAQ91665.1 - 3.4e-25 87.9 0.0 7.4e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain VanY PF02557.12 EAQ91665.1 - 0.15 11.8 0.1 0.6 9.9 0.0 1.9 2 1 1 3 3 3 0 D-alanyl-D-alanine carboxypeptidase CHZ PF09649.5 EAQ91666.1 - 0.00041 19.5 0.3 0.00076 18.6 0.2 1.4 1 0 0 1 1 1 1 Histone chaperone domain CHZ Cyclin PF08613.6 EAQ91667.1 - 1.4e-32 113.1 0.0 1.9e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EAQ91667.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain zf-C2H2 PF00096.21 EAQ91668.1 - 7.6e-07 29.1 10.4 0.038 14.3 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ91668.1 - 1.4e-05 25.0 10.2 0.019 15.2 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAQ91668.1 - 1 9.7 8.6 29 5.2 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain OTT_1508_deam PF14441.1 EAQ91669.1 - 1.4e-14 54.0 0.0 3.4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase FtsJ PF01728.14 EAQ91670.1 - 9.1e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPP_enzyme_C PF02775.16 EAQ91671.1 - 1.7e-23 82.8 0.0 2.7e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAQ91671.1 - 1.2e-22 80.1 0.0 5e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EAQ91671.1 - 7.5e-10 38.5 0.0 0.0019 17.7 0.0 3.0 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NTP_transf_3 PF12804.2 EAQ91671.1 - 0.009 16.1 0.8 0.18 11.8 0.6 2.7 2 1 0 2 2 2 1 MobA-like NTP transferase domain Glyco_hydro_43 PF04616.9 EAQ91672.1 - 6.7e-66 222.2 4.0 8.3e-66 221.9 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.8 EAQ91672.1 - 7.1e-10 38.7 0.1 8.1e-05 22.3 0.1 2.5 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) Glyco_hydro_62 PF03664.8 EAQ91673.1 - 1.2e-71 240.9 1.5 1.6e-71 240.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Herpes_gE PF02480.11 EAQ91674.1 - 0.00015 20.1 0.0 0.00019 19.8 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E FAM176 PF14851.1 EAQ91674.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 FAM176 family WBP-1 PF11669.3 EAQ91674.1 - 0.034 14.2 0.0 0.034 14.2 0.0 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 EphA2_TM PF14575.1 EAQ91674.1 - 0.06 13.7 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PBP1_TM PF14812.1 EAQ91674.1 - 0.22 11.8 5.8 0.38 11.0 4.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.6 EAQ91674.1 - 2.8 7.2 8.0 0.3 10.3 2.6 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.14 EAQ91674.1 - 3 7.0 9.8 16 4.6 5.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Anoctamin PF04547.7 EAQ91675.1 - 1.2e-73 248.2 0.0 5.4e-73 246.1 0.0 1.7 1 1 0 1 1 1 1 Calcium-activated chloride channel Beta-lactamase PF00144.19 EAQ91675.1 - 1.2e-36 126.4 1.9 1.9e-36 125.7 1.0 1.6 2 0 0 2 2 2 1 Beta-lactamase DUF221 PF02714.10 EAQ91677.1 - 5.9e-104 347.4 12.7 1.1e-103 346.4 8.8 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAQ91677.1 - 3e-42 143.8 3.2 1e-41 142.1 2.2 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EAQ91677.1 - 9.7e-23 79.8 0.0 9.9e-22 76.6 0.0 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EAQ91677.1 - 4.4e-08 33.5 0.0 1.2e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) NACHT PF05729.7 EAQ91678.1 - 3.3e-06 26.8 0.0 1.1e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ91678.1 - 3.5e-05 23.9 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 EAQ91678.1 - 0.047 12.2 0.0 0.12 10.9 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EAQ91678.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CBM_21 PF03370.8 EAQ91681.1 - 2.5e-36 124.0 1.0 4.8e-36 123.1 0.7 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Trypsin PF00089.21 EAQ91683.1 - 4.3e-07 29.7 0.2 0.02 14.4 0.0 2.4 1 1 0 2 2 2 2 Trypsin Trypsin_2 PF13365.1 EAQ91683.1 - 0.00069 19.5 0.5 0.019 14.9 0.3 2.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.15 EAQ91683.1 - 0.14 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) MULE PF10551.4 EAQ91685.1 - 1.2e-15 57.4 0.0 2.7e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ91685.1 - 0.00021 19.9 0.0 0.00033 19.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.10 EAQ91685.1 - 0.014 15.8 1.0 0.035 14.6 0.7 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain Rax2 PF12768.2 EAQ91685.1 - 0.48 9.5 0.2 0.77 8.9 0.2 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity GTSE1_N PF15259.1 EAQ91686.1 - 0.13 12.2 0.9 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 DUF605 PF04652.11 EAQ91686.1 - 0.48 9.7 13.4 0.58 9.5 9.3 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EAQ91686.1 - 1 7.5 15.1 1.2 7.3 10.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 EAQ91686.1 - 1.2 8.8 3.3 1.4 8.5 2.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM75 PF14650.1 EAQ91686.1 - 6.3 6.0 16.4 7.9 5.7 11.3 1.1 1 0 0 1 1 1 0 FAM75 family ADH_zinc_N PF00107.21 EAQ91687.1 - 3e-17 62.3 0.0 4.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ91687.1 - 2.3e-13 51.1 0.0 3.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EAQ91687.1 - 0.011 15.6 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EAQ91687.1 - 0.014 15.6 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EAQ91687.1 - 0.018 14.6 0.8 0.026 14.0 0.6 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DFP PF04127.10 EAQ91687.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 EAQ91687.1 - 0.051 12.9 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAQ91687.1 - 0.56 10.0 5.0 0.21 11.4 1.5 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase APG17 PF04108.7 EAQ91688.1 - 2.7e-83 280.0 0.5 5.6e-83 279.0 0.3 1.5 1 1 0 1 1 1 1 Autophagy protein Apg17 RmuC PF02646.11 EAQ91688.1 - 0.029 13.1 2.3 14 4.4 0.0 4.0 4 0 0 4 4 4 0 RmuC family GARS_C PF02843.11 EAQ91688.1 - 0.047 13.8 0.5 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain DinB_2 PF12867.2 EAQ91688.1 - 0.047 14.0 2.1 0.5 10.7 1.4 2.8 1 1 0 1 1 1 0 DinB superfamily Syntaxin-6_N PF09177.6 EAQ91688.1 - 0.14 12.5 2.2 26 5.2 0.1 3.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal WXG100 PF06013.7 EAQ91688.1 - 0.66 10.0 6.4 5.1 7.1 0.2 4.2 5 1 0 5 5 5 0 Proteins of 100 residues with WXG RIO1 PF01163.17 EAQ91689.1 - 8.5e-69 230.7 0.0 2.2e-68 229.3 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EAQ91689.1 - 0.00019 21.2 0.6 0.21 11.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EAQ91689.1 - 0.00098 18.2 0.7 0.021 13.9 0.5 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EAQ91689.1 - 0.06 12.9 0.8 0.14 11.6 0.6 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3464 PF11947.3 EAQ91689.1 - 1.7 8.0 7.7 0.083 12.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Ribonuc_L-PSP PF01042.16 EAQ91690.1 - 4.4e-19 68.4 0.0 6e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Op_neuropeptide PF08035.6 EAQ91690.1 - 0.036 13.6 0.1 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 Opioids neuropeptide MFS_1 PF07690.11 EAQ91691.1 - 2.9e-51 174.2 34.0 4.2e-51 173.7 23.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ91691.1 - 1.2e-13 50.4 15.5 1.9e-13 49.8 10.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Med22 PF06179.7 EAQ91691.1 - 9.2e-08 32.0 0.2 1.9e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex TRI12 PF06609.8 EAQ91691.1 - 0.00015 20.1 2.1 0.00024 19.4 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EAQ91691.1 - 0.037 12.0 6.4 0.025 12.6 2.7 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PseudoU_synth_1 PF01416.15 EAQ91692.1 - 6.7e-22 77.8 0.0 5.2e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase SKG6 PF08693.5 EAQ91693.1 - 0.001 18.3 0.0 0.0027 16.9 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EAQ91693.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EAQ91693.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.6 EAQ91693.1 - 0.11 12.1 2.8 0.16 11.4 1.9 1.2 1 0 0 1 1 1 0 Podoplanin Mucin PF01456.12 EAQ91693.1 - 0.17 11.6 19.6 0.037 13.7 10.9 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Presenilin PF01080.12 EAQ91694.1 - 0.066 12.0 3.4 0.094 11.5 2.3 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.6 EAQ91694.1 - 8 4.6 8.3 10 4.3 5.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 tRNA-synt_1c PF00749.16 EAQ91695.1 - 2.5e-74 249.7 0.0 3.2e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1e PF01406.14 EAQ91695.1 - 0.046 12.8 0.1 0.097 11.7 0.0 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Methyltransf_18 PF12847.2 EAQ91696.1 - 7.2e-09 36.2 0.0 1.5e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91696.1 - 6.2e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EAQ91696.1 - 0.00035 21.3 0.0 0.0015 19.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91696.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91696.1 - 0.0038 16.8 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91696.1 - 0.004 17.5 0.0 0.011 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ91696.1 - 0.005 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ91696.1 - 0.014 15.3 0.9 0.04 13.9 0.6 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EAQ91696.1 - 0.028 13.8 0.0 0.23 10.7 0.0 2.2 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.21 EAQ91698.1 - 2.9e-09 36.5 0.7 5.5e-09 35.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ91698.1 - 1.5e-08 34.3 0.0 3.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4360 PF14273.1 EAQ91699.1 - 9.9e-62 207.8 0.4 1.1e-61 207.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PEP_mutase PF13714.1 EAQ91701.1 - 2.3e-44 151.4 0.1 3.4e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UvrD_C_2 PF13538.1 EAQ91701.1 - 0.0012 18.9 0.0 0.0038 17.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ91701.1 - 0.036 14.1 0.1 0.086 12.9 0.1 1.6 1 0 0 1 1 1 0 Helicase associated domain PIF1 PF05970.9 EAQ91701.1 - 0.11 11.4 0.1 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Radical_SAM PF04055.16 EAQ91701.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily GMC_oxred_N PF00732.14 EAQ91702.1 - 5.7e-39 134.0 0.2 4.3e-36 124.5 0.3 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ91702.1 - 1.6e-24 86.8 0.0 3e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAQ91702.1 - 1.9e-05 24.6 3.8 2.1e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ91702.1 - 5.6e-05 22.2 3.3 0.00028 19.8 0.7 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ91702.1 - 8.1e-05 22.7 0.4 0.028 14.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ91702.1 - 0.0001 21.2 0.5 0.0003 19.7 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ91702.1 - 0.00045 20.1 2.0 0.0013 18.7 0.0 2.3 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ91702.1 - 0.0018 16.8 0.0 0.0031 16.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EAQ91702.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Fib_succ_major PF09603.5 EAQ91702.1 - 0.02 15.3 1.3 0.043 14.2 0.9 1.5 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) FAD_oxidored PF12831.2 EAQ91702.1 - 0.031 13.3 0.6 0.062 12.3 0.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ91702.1 - 0.037 13.1 1.0 0.06 12.4 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EAQ91702.1 - 0.044 12.8 0.2 0.044 12.8 0.1 1.6 2 0 0 2 2 1 0 FAD binding domain GIDA PF01134.17 EAQ91702.1 - 0.049 12.4 0.2 0.087 11.6 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A XylR_N PF06505.6 EAQ91702.1 - 0.1 12.0 0.1 9.8 5.6 0.0 2.7 2 0 0 2 2 2 0 Activator of aromatic catabolism 3HCDH_N PF02737.13 EAQ91702.1 - 2.4 7.8 4.0 2.4 7.7 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RdRP PF05183.7 EAQ91703.1 - 2.7e-122 409.3 0.1 3.7e-122 408.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.13 EAQ91704.1 - 3.6e-11 42.4 0.3 8.8e-11 41.1 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.14 EAQ91704.1 - 1e-07 32.1 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Peptidase_M14 PF00246.19 EAQ91706.1 - 1.9e-39 135.9 0.0 2.3e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase C2 PF00168.25 EAQ91707.1 - 1.2e-15 57.1 0.0 5.8e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain DIOX_N PF14226.1 EAQ91708.1 - 0.0031 18.0 0.0 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAQ91708.1 - 0.021 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_C2 PF00648.16 EAQ91710.1 - 4.8e-52 176.8 2.8 4.7e-36 124.2 0.4 2.6 3 0 0 3 3 3 2 Calpain family cysteine protease IER PF05760.7 EAQ91711.1 - 0.19 11.5 6.8 0.25 11.2 4.7 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Peptidase_C37 PF05416.7 EAQ91711.1 - 1.6 6.9 10.6 2.4 6.3 7.3 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Nop14 PF04147.7 EAQ91711.1 - 2.3 6.0 16.5 2.6 5.8 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EAQ91711.1 - 4.7 6.5 18.3 0.6 9.4 10.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EAQ91711.1 - 9.3 4.1 12.1 12 3.7 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp PF00026.18 EAQ91713.1 - 1.1e-41 143.1 0.7 1.5e-41 142.7 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ91713.1 - 0.0042 17.0 0.0 0.025 14.5 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Serglycin PF04360.7 EAQ91713.1 - 0.13 11.9 2.1 0.35 10.6 1.4 1.7 1 0 0 1 1 1 0 Serglycin Cofilin_ADF PF00241.15 EAQ91714.1 - 2.9e-22 78.8 0.0 6.1e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein GATase PF00117.23 EAQ91715.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Ribosomal_S7e PF01251.13 EAQ91716.1 - 1.3e-81 272.5 0.3 1.5e-81 272.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.7 EAQ91717.1 - 1.4e-26 92.3 3.4 2.3e-26 91.6 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ91717.1 - 6.8e-13 48.2 0.7 2e-12 46.8 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EAQ91717.1 - 1.6e-05 24.1 0.2 2.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynactin_p62 PF05502.8 EAQ91718.1 - 2e-197 656.7 0.0 2.3e-197 656.5 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 EAQ91718.1 - 3.7 7.5 7.3 0.1 12.5 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) BolA PF01722.13 EAQ91721.1 - 1.9e-14 53.3 0.0 3.6e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein EBP PF05241.7 EAQ91721.1 - 0.0011 18.0 2.9 0.0019 17.2 2.0 1.4 1 0 0 1 1 1 1 Emopamil binding protein Peptidase_S8 PF00082.17 EAQ91723.1 - 9.6e-48 162.7 0.4 3.1e-46 157.7 0.0 2.8 2 1 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 EAQ91723.1 - 4.6e-18 65.6 0.2 9.9e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EAQ91723.1 - 4.7e-11 42.2 1.5 1.4e-10 40.7 0.1 2.6 3 0 0 3 3 3 1 PA domain FlgD_ig PF13860.1 EAQ91723.1 - 8.3e-06 25.4 0.0 2.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 FlgD Ig-like domain DIM PF08194.7 EAQ91725.1 - 0.27 11.2 0.3 0.27 11.2 0.2 2.1 2 0 0 2 2 2 0 DIM protein UCR_Fe-S_N PF10399.4 EAQ91726.1 - 7.9 5.7 8.8 19 4.5 6.1 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal E1-E2_ATPase PF00122.15 EAQ91728.1 - 1.6e-51 174.5 0.8 1.6e-51 174.5 0.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAQ91728.1 - 1.7e-33 115.6 1.3 1.7e-33 115.6 0.9 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAQ91728.1 - 1.3e-32 113.9 0.2 1.2e-31 110.8 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAQ91728.1 - 1.1e-17 64.8 0.0 2.2e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ91728.1 - 5.3e-16 58.3 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAQ91728.1 - 1e-12 47.3 0.0 6e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EAQ91728.1 - 0.00075 19.1 0.1 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.4 EAQ91728.1 - 0.01 15.4 0.1 0.01 15.4 0.0 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Zn_clus PF00172.13 EAQ91729.1 - 2.6e-05 24.0 8.4 2.6e-05 24.0 5.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EAQ91729.1 - 0.00063 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding zf-C2H2 PF00096.21 EAQ91729.1 - 0.0042 17.3 4.8 0.0042 17.3 3.4 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ91729.1 - 0.015 15.6 3.3 0.015 15.6 2.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Saccharop_dh PF03435.13 EAQ91729.1 - 0.048 12.6 0.2 1 8.2 0.0 2.1 1 1 1 2 2 2 0 Saccharopine dehydrogenase FAD_binding_8 PF08022.7 EAQ91732.1 - 6.3e-15 54.9 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EAQ91732.1 - 5.1e-14 52.4 10.7 5.1e-14 52.4 7.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EAQ91732.1 - 4e-13 49.5 0.0 6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EAQ91732.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF4405 PF14358.1 EAQ91732.1 - 0.11 12.6 12.6 1.3 9.2 2.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) tRNA-synt_1d PF00750.14 EAQ91733.1 - 5.2e-80 268.9 5.1 1.1e-79 267.8 3.5 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EAQ91733.1 - 5.4e-26 90.8 0.2 1.5e-25 89.4 0.2 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EAQ91733.1 - 0.00013 22.4 0.0 0.00047 20.6 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF2203 PF09969.4 EAQ91733.1 - 0.95 9.6 4.7 3.8 7.7 1.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) p450 PF00067.17 EAQ91734.1 - 6.7e-57 193.0 0.0 8.6e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EAQ91735.1 - 3e-30 104.5 5.5 4.3e-30 104.0 3.8 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ91735.1 - 1.6e-12 47.0 0.0 3.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like SLAC1 PF03595.12 EAQ91736.1 - 4.5e-85 285.1 40.3 4.5e-85 285.1 28.0 4.9 5 1 2 7 7 7 1 Voltage-dependent anion channel RINGv PF12906.2 EAQ91736.1 - 0.012 15.6 0.2 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 RING-variant domain AF0941-like PF14591.1 EAQ91737.1 - 0.11 12.5 0.3 0.28 11.2 0.2 1.7 1 1 0 1 1 1 0 AF0941-like HeLo PF14479.1 EAQ91738.1 - 2.4e-07 30.7 9.6 0.00036 20.3 0.1 3.5 2 1 1 3 3 3 2 Prion-inhibition and propagation Pox_int_trans PF05718.7 EAQ91738.1 - 0.49 8.8 0.0 0.74 8.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor DUF3405 PF11885.3 EAQ91739.1 - 2.6e-162 540.5 0.7 3.1e-162 540.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) HATPase_c PF02518.21 EAQ91740.1 - 4.9e-20 71.3 0.1 1.1e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAQ91740.1 - 6.9e-20 71.1 0.0 1.9e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EAQ91740.1 - 2.7e-09 36.9 0.3 1.3e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EAQ91740.1 - 0.0087 16.1 0.0 0.082 13.0 0.0 2.6 2 0 0 2 2 2 1 GAF domain Glyco_hydro_61 PF03443.9 EAQ91741.1 - 6.4e-81 271.3 0.1 7.3e-81 271.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GPI-anchored PF10342.4 EAQ91741.1 - 0.21 12.0 1.5 5.7 7.4 0.9 2.7 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pilin PF00114.14 EAQ91741.1 - 1 10.0 4.6 1.7 9.4 1.9 2.2 1 1 1 2 2 2 0 Pilin (bacterial filament) Sugar_tr PF00083.19 EAQ91742.1 - 1.6e-83 280.8 21.4 2e-83 280.5 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ91742.1 - 1.4e-22 79.8 26.2 1.4e-22 79.8 18.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ91742.1 - 1.6e-06 26.6 1.9 3.3e-06 25.6 1.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GMC_oxred_N PF00732.14 EAQ91743.1 - 4.1e-31 108.2 0.1 6.6e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ91743.1 - 4.2e-30 104.9 0.0 6.7e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Apolipoprotein PF01442.13 EAQ91744.1 - 0.0012 18.3 6.7 0.035 13.6 2.9 3.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF3223 PF11523.3 EAQ91744.1 - 0.064 13.5 1.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) XH PF03469.9 EAQ91744.1 - 0.067 12.8 8.3 1.8 8.2 0.0 3.7 2 1 2 4 4 4 0 XH domain Alpha-E PF04168.7 EAQ91744.1 - 0.24 10.7 1.3 0.51 9.6 0.0 2.2 3 0 0 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. ApoLp-III PF07464.6 EAQ91744.1 - 0.95 9.4 15.9 11 6.0 3.2 3.7 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Syntaxin_2 PF14523.1 EAQ91744.1 - 1.6 8.8 11.0 3.5 7.7 0.7 4.6 2 1 2 5 5 5 0 Syntaxin-like protein Glyco_hydro_10 PF00331.15 EAQ91745.1 - 1.3e-77 260.9 0.0 1.7e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 TrkH PF02386.11 EAQ91747.1 - 6.7e-80 268.3 9.0 5e-51 173.3 0.8 3.1 3 0 0 3 3 3 3 Cation transport protein Ion_trans_2 PF07885.11 EAQ91747.1 - 2.9 7.6 10.1 0.19 11.4 2.6 2.3 2 0 0 2 2 2 0 Ion channel MFS_1 PF07690.11 EAQ91748.1 - 3.1e-34 118.2 24.3 3.1e-34 118.2 16.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ91748.1 - 1.1e-08 34.1 11.5 1.1e-08 34.1 8.0 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ91748.1 - 2.9e-06 25.7 4.6 2.9e-06 25.7 3.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Trp_DMAT PF11991.3 EAQ91749.1 - 3.5e-57 194.2 0.0 6.3e-41 140.7 0.0 2.0 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase ADH_zinc_N PF00107.21 EAQ91750.1 - 0.011 15.3 0.7 0.077 12.5 0.5 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EAQ91750.1 - 0.02 14.9 0.5 0.034 14.1 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EAQ91750.1 - 0.11 12.2 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Aminotran_1_2 PF00155.16 EAQ91751.1 - 0.0013 17.8 0.0 1.7 7.5 0.0 2.9 1 1 2 3 3 3 3 Aminotransferase class I and II Aminotran_MocR PF12897.2 EAQ91751.1 - 0.0024 16.4 0.0 0.3 9.5 0.0 2.4 2 1 1 3 3 3 2 Alanine-glyoxylate amino-transferase AMP-binding PF00501.23 EAQ91752.1 - 5.8e-55 186.3 0.0 8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EAQ91752.1 - 1.5e-25 90.7 0.1 1.2e-24 87.8 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EAQ91752.1 - 0.00011 22.1 0.8 0.0048 16.8 0.0 2.8 2 2 0 3 3 3 1 Alpha/beta hydrolase family PP-binding PF00550.20 EAQ91752.1 - 0.00065 19.9 2.0 0.0011 19.1 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site ProSAAS PF07259.7 EAQ91752.1 - 0.013 15.0 1.4 0.027 13.9 1.0 1.4 1 0 0 1 1 1 0 ProSAAS precursor Abhydrolase_5 PF12695.2 EAQ91752.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Clathrin-link PF09268.5 EAQ91753.1 - 0.089 11.8 0.4 0.18 10.8 0.3 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker NapE PF06796.6 EAQ91753.1 - 2.1 7.7 6.5 0.33 10.2 1.4 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE GMC_oxred_N PF00732.14 EAQ91754.1 - 2e-30 105.9 0.1 1.8e-27 96.2 0.1 2.8 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ91754.1 - 2.6e-30 105.6 0.0 4.9e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAQ91754.1 - 0.0013 18.7 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ91754.1 - 0.0083 15.0 0.6 0.046 12.6 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAQ91754.1 - 0.03 13.1 0.0 0.065 12.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EAQ91754.1 - 0.033 12.6 0.1 0.055 11.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EAQ91754.1 - 0.081 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EAQ91754.1 - 0.19 10.7 0.3 0.29 10.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ABC2_membrane PF01061.19 EAQ91755.1 - 9.1e-89 296.1 50.1 7.1e-47 159.2 17.2 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EAQ91755.1 - 1.7e-36 125.5 0.0 4.1e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EAQ91755.1 - 8.3e-26 89.6 6.6 6.1e-24 83.6 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EAQ91755.1 - 1.6e-08 33.9 34.2 0.00031 19.9 6.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EAQ91755.1 - 1.4e-06 27.8 0.0 0.004 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ91755.1 - 4.7e-06 26.7 0.5 0.024 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EAQ91755.1 - 0.00014 21.3 0.8 0.073 12.6 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EAQ91755.1 - 0.00041 20.5 0.2 0.13 12.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAQ91755.1 - 0.00067 19.6 1.3 0.34 10.8 0.4 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EAQ91755.1 - 0.001 18.5 0.9 0.33 10.3 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EAQ91755.1 - 0.0012 18.0 0.4 0.0052 15.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAQ91755.1 - 0.0019 18.4 0.0 2.7 8.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EAQ91755.1 - 0.0058 17.4 0.0 1.5 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EAQ91755.1 - 0.0082 15.6 0.3 1.1 8.8 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_trans_N PF14510.1 EAQ91755.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal AAA_19 PF13245.1 EAQ91755.1 - 0.017 14.8 1.0 4.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain AAA_33 PF13671.1 EAQ91755.1 - 0.028 14.2 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EAQ91755.1 - 0.037 13.6 0.5 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EAQ91755.1 - 0.052 14.0 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 EAQ91755.1 - 0.067 13.1 0.0 0.64 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EAQ91755.1 - 0.094 12.6 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EAQ91755.1 - 0.11 12.1 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 EAQ91755.1 - 0.17 10.7 0.1 3.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 EAQ91755.1 - 0.4 9.6 0.0 1.3 7.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.13 EAQ91756.1 - 6.2e-11 41.6 0.0 1.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ91756.1 - 1.2e-07 31.4 10.0 2.4e-07 30.5 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 EAQ91757.1 - 3.5e-75 252.5 1.2 3.9e-75 252.4 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p47_phox_C PF08944.6 EAQ91758.1 - 0.086 13.0 3.2 0.18 12.0 1.6 1.9 1 1 1 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain RVT_1 PF00078.22 EAQ91759.1 - 8.1e-16 58.0 0.0 7.5e-11 41.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EAQ91759.1 - 0.00036 20.3 3.7 0.00036 20.3 2.5 2.6 2 0 0 2 2 2 1 Zinc knuckle PurS PF02700.9 EAQ91759.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase zf-RVT PF13966.1 EAQ91759.1 - 0.57 10.5 5.1 0.12 12.7 0.2 2.4 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DDE_1 PF03184.14 EAQ91760.1 - 1.9e-23 82.7 0.0 3.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ91760.1 - 1.2e-11 43.9 0.1 2.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ91760.1 - 5e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SpoIIID PF12116.3 EAQ91760.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_23 PF13384.1 EAQ91760.1 - 0.059 13.0 0.2 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain rve PF00665.21 EAQ91761.1 - 3.8e-12 46.3 0.0 1.1e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EAQ91761.1 - 2.1e-08 33.8 0.0 4.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ91761.1 - 6.7e-08 32.0 0.2 2.5e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EAQ91761.1 - 0.024 14.3 0.0 0.077 12.7 0.0 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF3505 PF12013.3 EAQ91762.1 - 1.6e-18 66.9 0.3 3e-18 66.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EAQ91762.1 - 3.2e-12 46.2 0.2 1.1e-11 44.5 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ91762.1 - 6.6e-09 35.5 0.0 2.1e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ91762.1 - 1.1e-07 31.8 0.2 9.3e-06 25.5 0.2 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_10 PF13374.1 EAQ91766.1 - 1.7e-153 494.8 2.5 9.7e-14 50.7 0.0 12.5 11 1 1 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ91766.1 - 5.3e-133 433.2 0.0 5.6e-18 64.6 0.0 9.0 2 2 8 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ91766.1 - 8.4e-54 175.1 2.2 0.00063 19.3 0.0 11.5 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ91766.1 - 8e-31 103.6 0.9 0.43 10.9 0.0 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ91766.1 - 1.3e-22 77.8 0.1 1.7 8.7 0.0 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ91766.1 - 5.3e-22 76.4 0.1 3.9 7.2 0.0 10.7 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ91766.1 - 3.8e-21 75.1 0.0 0.0088 16.3 0.0 9.5 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ91766.1 - 5.1e-20 69.7 0.0 6.1 7.5 0.0 11.7 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ91766.1 - 1.3e-18 67.1 0.0 0.03 15.0 0.0 9.0 4 3 3 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ91766.1 - 2.2e-18 65.6 0.0 0.0019 17.7 0.0 7.1 4 2 3 7 7 7 5 TPR repeat TPR_8 PF13181.1 EAQ91766.1 - 2.8e-14 51.7 5.9 7.4 6.6 0.0 10.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Apc3 PF12895.2 EAQ91766.1 - 7.1e-14 51.7 0.0 0.029 14.5 0.0 7.3 2 2 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EAQ91766.1 - 1.7e-13 49.8 0.1 23 5.9 0.0 10.8 10 1 1 11 11 11 0 Tetratricopeptide repeat PPR PF01535.15 EAQ91766.1 - 1.3e-11 43.6 1.7 1.1e+02 3.1 0.0 10.9 11 0 0 11 11 11 0 PPR repeat TPR_5 PF12688.2 EAQ91766.1 - 4.7e-11 42.7 4.9 0.032 14.2 0.0 6.6 5 2 2 7 7 7 2 Tetratrico peptide repeat Rab5-bind PF09311.6 EAQ91766.1 - 1.1e-06 28.6 17.6 4 7.2 0.2 8.8 2 2 8 10 10 10 1 Rabaptin-like protein TPR_6 PF13174.1 EAQ91766.1 - 6.3e-06 26.2 13.8 11 6.6 0.0 9.3 11 0 0 11 11 9 0 Tetratricopeptide repeat RBD-FIP PF09457.5 EAQ91766.1 - 7.3e-06 25.6 2.2 46 3.9 0.0 7.0 5 0 0 5 5 5 0 FIP domain DUF832 PF05734.6 EAQ91766.1 - 1.4e-05 24.4 1.6 1.4 8.0 0.0 4.8 2 1 6 8 8 8 2 Herpesvirus protein of unknown function (DUF832) DUF2664 PF10867.3 EAQ91766.1 - 0.00018 22.0 13.4 40 4.9 0.0 9.2 7 2 3 11 11 11 0 Protein of unknown function (DUF2664) RVT_1 PF00078.22 EAQ91766.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EAQ91766.1 - 0.033 14.5 0.2 0.098 12.9 0.2 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF2680 PF10925.3 EAQ91766.1 - 0.1 12.4 9.5 2e+02 1.9 0.1 7.2 8 0 0 8 8 8 0 Protein of unknown function (DUF2680) RVT_1 PF00078.22 EAQ91768.1 - 4.7e-10 39.1 0.0 9.2e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S41 PF03572.13 EAQ91769.1 - 0.00018 20.9 0.0 0.00057 19.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family S41 ABC_membrane PF00664.18 EAQ91770.1 - 5.8e-37 127.5 12.7 7.5e-37 127.2 8.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ91770.1 - 1.4e-32 112.8 0.0 3.1e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EAQ91770.1 - 2e-06 27.9 0.0 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EAQ91770.1 - 3.6e-06 26.3 0.0 0.0012 18.1 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ91770.1 - 4.9e-06 26.7 0.0 0.068 13.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EAQ91770.1 - 4.5e-05 24.2 0.0 9.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAQ91770.1 - 7.1e-05 22.7 0.0 0.00092 19.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAQ91770.1 - 0.00017 21.6 0.1 0.0018 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAQ91770.1 - 0.0013 17.9 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EAQ91770.1 - 0.0028 17.8 0.0 0.019 15.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EAQ91770.1 - 0.0036 16.8 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EAQ91770.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EAQ91770.1 - 0.011 15.4 0.0 0.096 12.3 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 EAQ91770.1 - 0.012 14.9 0.0 0.035 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ91770.1 - 0.014 15.3 0.0 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAQ91770.1 - 0.018 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ91770.1 - 0.025 14.8 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EAQ91770.1 - 0.028 14.1 0.0 0.083 12.5 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAQ91770.1 - 0.029 14.8 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EAQ91770.1 - 0.036 14.0 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EAQ91770.1 - 0.05 12.6 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 EAQ91770.1 - 0.052 13.4 0.4 0.49 10.3 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EAQ91770.1 - 0.063 12.9 0.1 0.21 11.2 0.0 1.9 3 0 0 3 3 2 0 NACHT domain Kinesin PF00225.18 EAQ91771.1 - 6.5e-73 245.3 0.2 8.6e-73 244.9 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain TFIIA PF03153.8 EAQ91771.1 - 0.051 13.4 3.2 0.11 12.3 2.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIM24 PF01987.12 EAQ91772.1 - 1.2e-38 132.7 0.0 1.6e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peptidase_S8 PF00082.17 EAQ91774.1 - 1.5e-05 24.2 0.0 0.00013 21.2 0.0 1.9 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EAQ91774.1 - 0.0031 17.8 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) POPLD PF08170.7 EAQ91775.1 - 1.2 9.0 3.0 5.5 6.9 0.3 2.7 3 0 0 3 3 3 0 POPLD (NUC188) domain NUDIX_4 PF14815.1 EAQ91776.1 - 1.5e-16 59.8 0.0 4.1e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 EAQ91776.1 - 1.3e-13 51.1 0.0 3.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EAQ91776.1 - 4.2e-07 29.2 0.3 1.2e-06 27.8 0.2 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif UvrD_C_2 PF13538.1 EAQ91776.1 - 0.0018 18.4 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ91776.1 - 0.0018 16.1 0.0 0.0027 15.5 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EAQ91776.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase DUF605 PF04652.11 EAQ91776.1 - 0.51 9.6 8.5 0.98 8.7 5.9 1.4 1 0 0 1 1 1 0 Vta1 like DUF164 PF02591.10 EAQ91776.1 - 1 9.2 4.2 21 5.0 0.0 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain Whib PF02467.11 EAQ91776.1 - 8.6 6.7 8.3 2.7 8.3 0.4 3.3 3 0 0 3 3 3 0 Transcription factor WhiB FAA_hydrolase PF01557.13 EAQ91778.1 - 6.3e-61 205.6 0.0 7.5e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.17 EAQ91779.1 - 1.4e-63 215.0 0.0 2.5e-52 177.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.14 EAQ91780.1 - 1.7e-82 277.3 0.0 2.3e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ91780.1 - 0.00077 19.3 0.0 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ91780.1 - 0.0037 16.2 0.4 0.094 11.5 0.4 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ91780.1 - 0.054 13.5 1.9 0.13 12.2 1.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAQ91780.1 - 0.076 12.1 0.2 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EAQ91780.1 - 0.1 11.5 0.2 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glyoxalase PF00903.20 EAQ91781.1 - 9.2e-09 35.3 6.1 1.9e-05 24.6 2.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EAQ91781.1 - 1.1e-06 29.2 2.5 0.00072 20.1 0.2 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EAQ91781.1 - 1.2e-05 25.2 0.2 0.003 17.5 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Isochorismatase PF00857.15 EAQ91782.1 - 1.1e-18 67.7 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipoxygenase PF00305.14 EAQ91782.1 - 0.069 11.1 0.0 0.088 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase DHDPS PF00701.17 EAQ91783.1 - 3.8e-29 101.1 0.0 4.8e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Abhydrolase_6 PF12697.2 EAQ91784.1 - 2.3e-08 34.1 1.1 3.6e-08 33.5 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ91784.1 - 0.0022 17.7 0.1 0.0033 17.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MHYT PF03707.11 EAQ91785.1 - 5.2e-10 39.2 21.4 9.7e-06 25.6 0.5 4.6 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat Fringe PF02434.11 EAQ91786.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EAQ91786.1 - 0.0017 18.0 0.8 0.0035 17.0 0.6 1.5 1 0 0 1 1 1 1 PAN domain adh_short PF00106.20 EAQ91787.1 - 1.8e-22 80.0 5.3 2.6e-22 79.5 3.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ91787.1 - 3.7e-08 33.4 0.1 4.7e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ91787.1 - 3.2e-07 30.2 3.5 5.2e-07 29.5 2.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ91787.1 - 0.00011 21.7 0.1 0.00028 20.4 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ91787.1 - 0.00055 18.9 0.5 0.00089 18.2 0.4 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EAQ91787.1 - 0.0062 16.5 1.9 0.014 15.4 1.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EAQ91787.1 - 0.0067 15.9 0.2 0.013 15.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.5 EAQ91787.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cutinase PF01083.17 EAQ91789.1 - 8.7e-52 175.4 7.7 1.2e-51 175.0 5.4 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 EAQ91789.1 - 5.1e-12 45.2 19.6 5.1e-12 45.2 13.6 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_6 PF12697.2 EAQ91789.1 - 0.00022 21.1 0.2 0.00057 19.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EAQ91789.1 - 0.002 17.5 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EAQ91789.1 - 0.004 16.7 0.1 0.012 15.1 0.0 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ91789.1 - 0.0064 16.2 2.2 0.012 15.3 0.9 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 EAQ91790.1 - 9.5e-05 21.1 0.0 0.00014 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EAQ91791.1 - 1.3e-13 51.1 0.1 2.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ91791.1 - 5.7e-06 26.1 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ91791.1 - 0.00016 21.5 0.0 0.00041 20.2 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Hexapep PF00132.19 EAQ91792.1 - 6.1e-05 22.3 15.6 0.0031 16.9 5.7 2.8 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF3776 PF12618.3 EAQ91793.1 - 0.085 13.4 1.2 0.16 12.5 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Peptidase_M28 PF04389.12 EAQ91794.1 - 2.5e-36 125.1 0.0 4.4e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAQ91794.1 - 1.1e-10 41.1 0.1 1.2e-09 37.7 0.0 2.5 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.23 EAQ91794.1 - 1.1e-05 24.9 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_hydro_10 PF00331.15 EAQ91795.1 - 3e-102 341.9 0.0 3.6e-102 341.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EAQ91795.1 - 8.4e-15 54.1 11.0 2.1e-14 52.8 7.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Hemerythrin PF01814.18 EAQ91796.1 - 7.4e-17 61.7 3.5 7.4e-17 61.7 2.5 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF1031 PF06275.6 EAQ91796.1 - 0.0068 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1031) KfrA_N PF11740.3 EAQ91796.1 - 0.056 13.8 1.6 0.14 12.6 1.1 1.7 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Myb_DNA-bind_4 PF13837.1 EAQ91796.1 - 0.7 10.0 3.7 1.6 8.8 0.2 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain FCD PF07729.7 EAQ91796.1 - 5 7.4 6.6 2.5 8.4 0.1 2.4 2 1 0 2 2 2 0 FCD domain Fungal_trans_2 PF11951.3 EAQ91797.1 - 1.9e-05 23.4 3.1 2.6e-05 22.9 2.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ91797.1 - 0.00053 19.8 1.8 0.00098 18.9 1.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EAQ91798.1 - 1.4e-52 178.8 0.0 1.9e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EAQ91800.1 - 1.8e-17 64.0 4.0 2.3e-16 60.3 2.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ91800.1 - 5e-05 23.1 2.0 0.00013 21.7 1.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ91800.1 - 0.00028 20.5 0.1 0.0013 18.3 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EAQ91800.1 - 0.036 14.2 0.1 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain ATP-synt_8 PF00895.15 EAQ91801.1 - 3.2 8.0 6.8 0.13 12.5 0.3 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 DUF2196 PF09962.4 EAQ91802.1 - 3.3e-24 84.4 1.3 5.7e-24 83.6 0.9 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Apolipoprotein PF01442.13 EAQ91802.1 - 0.0074 15.8 0.2 0.014 14.9 0.2 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3618 PF12277.3 EAQ91802.1 - 0.017 15.1 0.2 0.063 13.3 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF3150 PF11348.3 EAQ91802.1 - 0.037 13.1 0.1 0.055 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) zf-H2C2_5 PF13909.1 EAQ91802.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Adeno_E4_ORF3 PF06931.6 EAQ91802.1 - 0.051 13.6 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein FdhE PF04216.7 EAQ91802.1 - 0.052 13.2 2.6 0.6 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DUF3584 PF12128.3 EAQ91802.1 - 0.097 9.9 1.0 0.14 9.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rootletin PF15035.1 EAQ91802.1 - 0.098 12.6 2.5 0.12 12.2 0.5 1.8 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 EAQ91802.1 - 0.098 12.2 1.2 0.15 11.6 0.8 1.2 1 0 0 1 1 1 0 IncA protein zf-Di19 PF05605.7 EAQ91802.1 - 0.43 10.7 2.8 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding NmrA PF05368.8 EAQ91803.1 - 3.5e-23 82.0 2.1 5e-22 78.3 0.9 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EAQ91803.1 - 3.5e-06 27.1 0.3 4.7e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ91803.1 - 0.2 10.2 0.6 0.57 8.8 0.1 1.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family HD PF01966.17 EAQ91805.1 - 0.026 14.5 0.1 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 HD domain AMP-binding PF00501.23 EAQ91806.1 - 5.1e-33 114.0 0.0 1.3e-32 112.7 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EAQ91806.1 - 8.8e-30 103.4 0.0 1.6e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAQ91806.1 - 3.5e-11 43.0 0.0 5.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EAQ91806.1 - 6.9e-05 23.0 0.0 0.0002 21.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EAQ91806.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Sugar_tr PF00083.19 EAQ91807.1 - 4.9e-32 111.0 26.6 2e-22 79.3 5.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAQ91807.1 - 1.5e-08 33.8 38.2 2.2e-07 29.9 10.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily KIAA1328 PF15369.1 EAQ91808.1 - 1.8 8.3 13.9 2.8 7.6 9.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 p450 PF00067.17 EAQ91809.1 - 5.8e-51 173.4 0.0 6.7e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 EAQ91810.1 - 8.3e-24 84.2 0.0 1.4e-23 83.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) CobT PF06213.7 EAQ91810.1 - 0.025 13.7 14.2 0.035 13.2 9.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EAQ91810.1 - 0.2 9.6 5.8 0.25 9.3 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.8 EAQ91810.1 - 0.26 9.4 5.4 0.36 8.9 3.7 1.1 1 0 0 1 1 1 0 Menin Paf1 PF03985.8 EAQ91810.1 - 1.4 7.5 16.6 2 7.0 11.5 1.1 1 0 0 1 1 1 0 Paf1 CENP-T PF15511.1 EAQ91810.1 - 2 7.5 12.2 3.1 6.9 8.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EAQ91810.1 - 4.8 4.9 19.5 6.3 4.5 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family ketoacyl-synt PF00109.21 EAQ91811.1 - 1.4e-72 244.2 0.0 2.6e-72 243.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ91811.1 - 8.6e-63 212.5 0.0 1.4e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EAQ91811.1 - 1.6e-54 184.3 0.1 4.2e-54 182.9 0.1 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAQ91811.1 - 2.7e-46 157.5 0.2 9.3e-46 155.7 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EAQ91811.1 - 4.7e-31 107.0 0.0 1.9e-30 105.1 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EAQ91811.1 - 5e-21 75.1 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EAQ91811.1 - 3.7e-11 43.1 0.8 8.4e-11 41.9 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EAQ91811.1 - 4.5e-07 29.4 0.0 1.5e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EAQ91811.1 - 0.0001 21.3 0.1 0.00033 19.7 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EAQ91811.1 - 0.026 14.1 0.1 0.12 12.0 0.1 2.2 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.7 EAQ91811.1 - 0.086 12.6 0.2 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 EAQ91811.1 - 0.13 11.4 0.1 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family ThiF PF00899.16 EAQ91811.1 - 0.17 11.6 0.9 0.45 10.3 0.6 1.6 1 0 0 1 1 1 0 ThiF family ELFV_dehydrog PF00208.16 EAQ91811.1 - 0.21 11.1 0.0 5.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Fer4 PF00037.22 EAQ91812.1 - 3.7e-14 51.6 16.4 5.3e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EAQ91812.1 - 3.7e-12 46.4 11.0 6e-12 45.7 7.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EAQ91812.1 - 7.2e-10 38.5 21.9 2.5e-08 33.5 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EAQ91812.1 - 8.7e-10 38.7 11.0 1.7e-09 37.8 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EAQ91812.1 - 1.2e-09 38.7 9.3 0.00021 21.9 0.3 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EAQ91812.1 - 2e-09 37.1 32.6 5.6e-06 26.1 8.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 EAQ91812.1 - 1.3e-08 34.7 31.6 7.8e-06 25.8 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EAQ91812.1 - 3.3e-08 32.9 15.0 0.00043 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EAQ91812.1 - 9.9e-08 31.5 17.0 0.00051 19.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EAQ91812.1 - 3.9e-06 27.1 10.0 0.00042 20.6 7.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EAQ91812.1 - 4.1e-06 26.6 13.1 0.00044 20.3 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EAQ91812.1 - 1.5e-05 25.3 9.7 0.0042 17.4 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EAQ91812.1 - 0.0081 16.5 14.6 0.32 11.4 2.9 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EAQ91812.1 - 0.015 15.8 12.8 0.32 11.5 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EAQ91812.1 - 0.036 14.6 17.7 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EAQ91812.1 - 0.13 12.3 4.9 0.29 11.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain zf-CCCH PF00642.19 EAQ91814.1 - 2.5e-10 39.7 8.2 3.5e-05 23.3 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAQ91814.1 - 0.16 12.0 17.5 0.23 11.5 3.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Glyco_tranf_2_3 PF13641.1 EAQ91815.1 - 1.4e-11 44.6 0.6 1.8e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAQ91815.1 - 2e-10 40.2 2.2 2.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EAQ91815.1 - 8e-10 38.7 6.8 2.2e-09 37.3 4.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 EAQ91815.1 - 2.9e-07 29.2 0.2 5.1e-06 25.1 0.1 2.2 1 1 0 1 1 1 1 Chitin synthase AWPM-19 PF05512.6 EAQ91815.1 - 0.046 13.7 2.9 0.1 12.5 2.0 1.6 1 0 0 1 1 1 0 AWPM-19-like family Fringe PF02434.11 EAQ91816.1 - 4.4e-07 29.3 3.1 1.8e-05 24.0 0.8 3.0 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 EAQ91816.1 - 0.00089 18.9 3.4 0.0027 17.3 2.4 1.8 1 0 0 1 1 1 1 PAN domain Cupin_1 PF00190.17 EAQ91817.1 - 6.6e-24 83.9 0.0 2.2e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EAQ91817.1 - 4.5e-18 64.5 0.7 1.2e-08 34.3 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.7 EAQ91817.1 - 7.7e-06 25.2 0.0 0.011 15.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_4 PF08007.7 EAQ91817.1 - 0.092 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein BNR_2 PF13088.1 EAQ91818.1 - 0.00029 20.2 0.4 0.026 13.8 0.1 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EAQ91818.1 - 1.6 8.8 4.4 1.8 8.7 0.3 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat MFS_1 PF07690.11 EAQ91819.1 - 2e-27 95.8 29.7 2e-27 95.8 20.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ91819.1 - 1.1e-15 57.2 2.8 1.1e-15 57.2 2.0 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ91819.1 - 0.0037 15.5 3.4 0.0075 14.5 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF680 PF05079.7 EAQ91819.1 - 0.17 12.4 0.4 0.34 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF680) ADC PF06314.6 EAQ91820.1 - 1.6e-10 40.7 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.14 EAQ91820.1 - 3.7e-10 39.4 0.1 4.5e-07 29.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAQ91820.1 - 0.0055 16.7 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ91820.1 - 0.031 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1344 PF07076.6 EAQ91820.1 - 0.16 11.5 0.1 0.41 10.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) LigB PF02900.13 EAQ91821.1 - 4.3e-21 75.1 0.0 5.3e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NUDIX PF00293.23 EAQ91823.1 - 1.7e-05 24.4 0.0 6e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain CENP-P PF13096.1 EAQ91823.1 - 0.051 12.9 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Peptidase_S15 PF02129.13 EAQ91824.1 - 3.1e-42 144.8 0.6 4.1e-42 144.4 0.4 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EAQ91824.1 - 1.2e-22 80.9 0.1 2.3e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EAQ91824.1 - 8e-06 25.8 0.3 1.8e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ91824.1 - 8.5e-05 22.3 0.1 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ91824.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase FAA_hydrolase PF01557.13 EAQ91825.1 - 2.2e-48 164.5 0.0 3e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EAQ91825.1 - 3.4e-19 68.8 0.0 4.3e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Cupin_2 PF07883.6 EAQ91826.1 - 1.8e-09 36.9 0.0 3.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EAQ91826.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Aldedh PF00171.17 EAQ91827.1 - 1.4e-15 56.6 0.1 1e-14 53.7 0.1 2.1 2 1 0 2 2 2 1 Aldehyde dehydrogenase family YlbD_coat PF14071.1 EAQ91832.1 - 0.15 12.1 0.0 0.67 10.0 0.0 2.0 2 0 0 2 2 2 0 Putative coat protein Med9 PF07544.8 EAQ91832.1 - 0.19 11.4 0.1 0.58 9.9 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3617 PF12276.3 EAQ91833.1 - 0.13 11.7 0.2 3.3 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3617) Methyltransf_23 PF13489.1 EAQ91834.1 - 1.4e-22 80.1 0.0 2.4e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91834.1 - 2.8e-09 37.5 0.0 2.9e-08 34.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91834.1 - 1.3e-07 31.9 0.0 8.1e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91834.1 - 1.8e-07 30.8 0.0 2.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91834.1 - 6.6e-07 29.7 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ91834.1 - 0.00041 19.5 0.0 0.01 14.9 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EAQ91834.1 - 0.00066 19.2 0.0 0.034 13.6 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EAQ91834.1 - 0.0013 19.0 0.0 0.0044 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAQ91834.1 - 0.0049 16.8 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EAQ91834.1 - 0.0054 16.7 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAQ91834.1 - 0.0095 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 EAQ91834.1 - 0.21 10.7 0.0 1 8.4 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G PIF1 PF05970.9 EAQ91836.1 - 4e-33 114.8 0.0 2.3e-26 92.6 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAQ91836.1 - 4.1e-07 29.7 0.0 2.6e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ91836.1 - 2.6e-05 24.2 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ91836.1 - 5.7e-05 21.0 0.0 0.0028 15.5 0.0 2.0 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.1 EAQ91836.1 - 0.00018 21.1 0.1 0.00038 20.1 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 EAQ91836.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Torsin Viral_helicase1 PF01443.13 EAQ91836.1 - 0.17 11.3 0.5 5.1 6.5 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RVT_1 PF00078.22 EAQ91837.1 - 4.2e-25 88.3 0.0 9.3e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ91837.1 - 1e-21 76.7 0.0 9.7e-21 73.5 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase PAP2 PF01569.16 EAQ91837.1 - 1.4e-17 63.5 7.8 2.6e-17 62.6 5.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily Exo_endo_phos PF03372.18 EAQ91837.1 - 1.2e-08 35.2 0.1 2.4e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ91837.1 - 0.011 16.1 4.1 0.18 12.2 2.4 2.8 1 1 1 2 2 2 0 SlyX CorA PF01544.13 EAQ91837.1 - 0.079 11.9 1.9 0.16 10.9 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ91837.1 - 0.43 10.6 5.9 0.15 12.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Mnd1 PF03962.10 EAQ91837.1 - 0.47 10.0 1.9 1.1 8.8 1.3 1.5 1 0 0 1 1 1 0 Mnd1 family DUF853 PF05872.7 EAQ91838.1 - 1.6 6.9 10.7 2.5 6.3 7.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MULE PF10551.4 EAQ91839.1 - 1.6e-06 28.1 0.0 3.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 EAQ91839.1 - 0.13 12.2 0.0 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 DDE domain Helicase_C PF00271.26 EAQ91840.1 - 3.9e-08 33.0 0.1 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ91840.1 - 2.4e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ91840.1 - 0.012 15.3 0.0 0.053 13.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MULE PF10551.4 EAQ91842.1 - 4.6e-12 45.9 0.0 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ91842.1 - 5.7e-06 25.1 0.1 1.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Transposase, Mutator family Helitron_like_N PF14214.1 EAQ91843.1 - 2.4e-23 82.7 1.9 4.8e-11 42.7 0.0 2.4 1 1 1 2 2 2 2 Helitron helicase-like domain at N-terminus ResIII PF04851.10 EAQ91843.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EAQ91843.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EAQ91843.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase GCK PF07802.6 EAQ91844.1 - 0.0097 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 GCK domain La PF05383.12 EAQ91844.1 - 0.07 12.9 0.0 0.24 11.2 0.0 2.0 1 0 0 1 1 1 0 La domain Glyco_hydro_61 PF03443.9 EAQ91845.1 - 4.4e-59 199.9 0.0 5.2e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RVT_2 PF07727.9 EAQ91846.1 - 5e-13 48.5 0.0 8.7e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91846.1 - 2.9e-09 37.0 0.1 2.6e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ91846.1 - 1.4e-05 24.6 0.4 3.5e-05 23.3 0.3 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain EI24 PF07264.6 EAQ91847.1 - 7.2e-06 25.5 1.5 7.2e-06 25.5 1.0 2.2 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Lip_A_acyltrans PF03279.8 EAQ91847.1 - 3.7 6.3 5.2 13 4.5 0.5 2.3 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase DUF805 PF05656.9 EAQ91847.1 - 8.3 6.2 9.1 4.7 7.0 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF805) MFS_1 PF07690.11 EAQ91850.1 - 3e-15 55.8 47.9 7.5e-10 38.0 12.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily ketoacyl-synt PF00109.21 EAQ91852.1 - 5e-65 219.4 0.1 7.7e-65 218.8 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAQ91852.1 - 6.4e-38 129.2 0.0 1.1e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EAQ91852.1 - 2.8e-10 40.0 0.1 6.3e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 EAQ91852.1 - 0.019 13.9 0.1 0.057 12.3 0.1 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain KR PF08659.5 EAQ91853.1 - 4.8e-53 179.5 0.1 8.8e-53 178.6 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAQ91853.1 - 1.7e-36 125.6 0.1 1.7e-36 125.6 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EAQ91853.1 - 1.5e-12 47.2 1.4 2.3e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EAQ91853.1 - 9.7e-12 45.2 0.0 2.3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EAQ91853.1 - 2.3e-11 44.6 0.1 7.8e-11 42.9 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EAQ91853.1 - 1.4e-07 31.6 0.1 3.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EAQ91853.1 - 1.1e-05 25.1 0.0 3.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EAQ91853.1 - 3.9e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91853.1 - 6.3e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91853.1 - 0.00087 19.7 0.0 0.0047 17.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain E1-E2_ATPase PF00122.15 EAQ91854.1 - 3.2e-64 216.1 1.9 3.2e-64 216.1 1.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ91854.1 - 5e-31 108.7 0.0 7.5e-30 104.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EAQ91854.1 - 6.2e-31 107.3 6.1 6.2e-31 107.3 4.2 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EAQ91854.1 - 2.8e-17 62.4 0.0 5.6e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAQ91854.1 - 4.4e-16 58.1 2.4 7.7e-16 57.3 0.1 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAQ91854.1 - 4.4e-15 56.3 0.0 1.2e-14 54.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ91854.1 - 0.00074 19.1 0.3 0.004 16.7 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SieB PF14163.1 EAQ91854.1 - 0.75 9.3 3.9 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B MFS_1 PF07690.11 EAQ91855.1 - 1.4e-22 79.9 16.7 4.2e-22 78.3 11.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ91855.1 - 0.00034 18.9 0.3 0.00034 18.9 0.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OxoDH_E1alpha_N PF12573.3 EAQ91856.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF1857 PF08982.6 EAQ91857.1 - 8.9e-49 164.9 0.0 1.1e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) CFEM PF05730.6 EAQ91858.1 - 3.8e-07 29.8 10.0 1.2e-06 28.2 6.9 1.8 1 1 0 1 1 1 1 CFEM domain PDR_assoc PF08370.6 EAQ91858.1 - 5 6.6 9.4 12 5.5 0.6 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Cro PF09048.5 EAQ91859.1 - 0.099 12.2 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 Cro HsbA PF12296.3 EAQ91860.1 - 0.084 12.7 1.7 0.12 12.2 1.1 1.2 1 0 0 1 1 1 0 Hydrophobic surface binding protein A SNARE_assoc PF09335.6 EAQ91861.1 - 7.8e-10 39.0 1.0 7.8e-10 39.0 0.7 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein YrhC PF14143.1 EAQ91861.1 - 0.034 14.0 0.1 0.081 12.8 0.1 1.6 1 0 0 1 1 1 0 YrhC-like protein DUF3671 PF12420.3 EAQ91861.1 - 0.26 11.2 1.4 2.1 8.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF3278 PF11683.3 EAQ91861.1 - 0.43 10.5 4.1 0.21 11.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF2142 PF09913.4 EAQ91861.1 - 1.1 7.8 9.2 0.13 10.9 2.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) DUF202 PF02656.10 EAQ91861.1 - 3.4 7.9 12.1 6.8 6.9 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) ABC2_membrane_5 PF13346.1 EAQ91861.1 - 8.7 5.5 10.5 0.17 11.1 0.3 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein FAD_binding_3 PF01494.14 EAQ91862.1 - 3e-16 59.4 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Ank PF00023.25 EAQ91863.1 - 1.8e-05 24.3 0.0 0.00049 19.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EAQ91863.1 - 0.00074 19.5 0.0 0.0056 16.7 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EAQ91863.1 - 0.0029 17.9 0.0 0.0076 16.5 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ91863.1 - 0.0077 16.4 0.0 0.035 14.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ91863.1 - 0.036 14.5 0.0 0.094 13.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) COG5 PF10392.4 EAQ91864.1 - 1.4e-42 144.8 2.8 1.4e-42 144.8 1.9 2.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF2434 PF10361.4 EAQ91865.1 - 3.7e-134 446.4 6.3 4.6e-134 446.1 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) UPF0182 PF03699.8 EAQ91865.1 - 0.017 13.0 1.2 0.023 12.6 0.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) zf-H2C2_2 PF13465.1 EAQ91866.1 - 6.1e-06 26.2 6.7 6.7e-06 26.1 2.8 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ91866.1 - 3.6e-05 23.7 15.3 0.0039 17.4 2.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ91866.1 - 0.00021 21.4 14.3 0.046 14.0 2.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Colipase PF01114.13 EAQ91868.1 - 0.014 14.9 4.3 0.023 14.1 3.0 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain PepSY_2 PF13670.1 EAQ91868.1 - 7.9 6.4 6.3 9.1 6.2 0.6 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ank_2 PF12796.2 EAQ91869.1 - 7.9e-82 269.7 53.6 3.3e-16 59.4 0.1 9.4 2 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ91869.1 - 6.8e-56 183.4 66.9 3.3e-06 26.6 0.1 18.9 19 0 0 19 19 19 11 Ankyrin repeat Ank_4 PF13637.1 EAQ91869.1 - 1.7e-41 139.8 27.9 1e-05 25.8 0.4 11.2 6 2 6 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ91869.1 - 1e-40 136.8 50.5 7.4e-05 22.8 2.1 14.6 5 2 10 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91869.1 - 9.8e-40 130.6 38.3 0.00017 21.5 0.1 17.3 19 0 0 19 19 19 9 Ankyrin repeat AAA_22 PF13401.1 EAQ91869.1 - 1.9e-06 28.0 0.0 4.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAQ91869.1 - 0.045 13.3 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EAQ91869.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.6 5 1 0 5 5 5 0 AAA ATPase domain RNA_helicase PF00910.17 EAQ91869.1 - 0.33 11.1 0.1 0.99 9.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Ctr PF04145.10 EAQ91870.1 - 0.13 12.2 1.2 0.88 9.6 0.0 2.4 2 1 0 2 2 2 0 Ctr copper transporter family APOBEC_C PF05240.9 EAQ91870.1 - 0.2 11.0 1.1 0.34 10.3 0.7 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Fasciclin PF02469.17 EAQ91872.1 - 2.9e-18 66.0 0.0 1.2e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain OsmC PF02566.14 EAQ91874.1 - 1.3e-20 73.4 0.0 1.8e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein RTA1 PF04479.8 EAQ91875.1 - 1.3e-33 116.3 7.1 1.7e-33 116.0 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.1 EAQ91875.1 - 0.035 13.8 6.1 1.7 8.3 0.1 2.9 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Fungal_trans_2 PF11951.3 EAQ91876.1 - 0.00057 18.5 0.0 0.00077 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hexapep PF00132.19 EAQ91877.1 - 2.5e-15 55.1 18.2 7e-12 44.2 3.2 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAQ91877.1 - 9.8e-11 41.0 21.5 1.4e-08 34.1 3.2 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EAQ91877.1 - 0.00033 20.6 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase XFP_N PF09364.5 EAQ91879.1 - 2.7e-114 381.6 0.2 2e-112 375.5 0.1 2.1 1 1 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EAQ91879.1 - 2e-58 196.9 0.0 3e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 EAQ91879.1 - 0.00026 20.5 0.1 0.007 15.9 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.19 EAQ91879.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain FAD_binding_4 PF01565.18 EAQ91882.1 - 6.4e-18 64.5 1.0 6.4e-18 64.5 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain E1-E2_ATPase PF00122.15 EAQ91884.1 - 2.9e-56 190.0 1.4 2.9e-56 190.0 1.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAQ91884.1 - 8e-48 162.3 1.1 8e-48 162.3 0.7 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAQ91884.1 - 4.9e-28 99.0 0.0 3e-27 96.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ91884.1 - 1.3e-19 69.9 0.0 6.8e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAQ91884.1 - 4.1e-15 56.4 0.0 1e-14 55.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAQ91884.1 - 1.3e-07 30.9 0.1 6.5e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EAQ91884.1 - 2.3e-06 27.3 0.7 8.8e-05 22.2 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_H PF00075.19 EAQ91885.1 - 0.048 14.0 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 RNase H RNase_H PF00075.19 EAQ91886.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 RNase H Polysacc_deac_1 PF01522.16 EAQ91886.1 - 0.17 11.5 0.6 0.42 10.2 0.5 1.5 1 1 0 1 1 1 0 Polysaccharide deacetylase SprT-like PF10263.4 EAQ91888.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 SprT-like family DUF1996 PF09362.5 EAQ91890.1 - 8.9e-85 284.0 4.7 2.1e-84 282.8 1.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) APH PF01636.18 EAQ91892.1 - 5.8e-16 58.9 4.1 6.2e-16 58.8 1.2 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RVT_2 PF07727.9 EAQ91892.1 - 4.7e-09 35.5 0.1 8.6e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91892.1 - 7.4e-09 35.7 0.0 2.3e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ91892.1 - 1.3e-05 24.7 0.4 3.1e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Choline_kinase PF01633.15 EAQ91892.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DDE_3 PF13358.1 EAQ91893.1 - 6.3e-18 64.9 0.2 9.5e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EAQ91893.1 - 0.037 14.1 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain PP_kinase_N PF13089.1 EAQ91893.1 - 0.093 12.8 0.2 0.14 12.2 0.2 1.5 1 1 0 1 1 1 0 Polyphosphate kinase N-terminal domain Glyco_hydro_11 PF00457.12 EAQ91894.1 - 8.5e-64 214.2 14.8 1e-63 213.9 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 GMC_oxred_N PF00732.14 EAQ91895.1 - 1e-53 182.4 0.0 1.4e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ91895.1 - 1.5e-29 103.0 0.0 2.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAQ91895.1 - 7.6e-06 25.0 0.0 0.006 15.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAQ91895.1 - 0.00017 20.6 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAQ91895.1 - 0.00066 19.6 0.1 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ91895.1 - 0.0021 17.0 0.0 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ91895.1 - 0.0021 17.9 0.0 0.0051 16.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ91895.1 - 0.029 12.8 0.0 0.51 8.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EAQ91895.1 - 0.051 13.6 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAQ91895.1 - 0.074 11.8 0.0 6.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Photo_RC PF00124.14 EAQ91896.1 - 0.0019 17.2 1.1 0.0019 17.2 0.7 1.5 2 0 0 2 2 2 1 Photosynthetic reaction centre protein GFA PF04828.9 EAQ91897.1 - 2e-14 53.2 0.2 3.2e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EAQ91897.1 - 0.0064 16.1 0.2 0.0064 16.1 0.2 2.2 3 0 0 3 3 3 1 Nudix N-terminal Cys_rich_CWC PF14375.1 EAQ91897.1 - 1.1 9.1 6.5 0.57 10.1 2.0 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC 2-Hacid_dh_C PF02826.14 EAQ91898.1 - 4.2e-41 140.0 0.2 1.5e-26 92.6 0.0 2.5 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAQ91898.1 - 0.025 15.0 0.0 0.14 12.5 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M44 PF03410.8 EAQ91898.1 - 0.035 12.3 0.0 0.046 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein G1 NAD_binding_10 PF13460.1 EAQ91898.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_8 PF13450.1 EAQ91899.1 - 0.0081 16.1 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ91899.1 - 0.032 13.1 0.1 0.061 12.2 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Herpes_ori_bp PF02399.10 EAQ91901.1 - 0.027 12.4 0.1 0.038 11.9 0.1 1.1 1 0 0 1 1 1 0 Origin of replication binding protein HK97-gp10_like PF04883.7 EAQ91902.1 - 0.13 13.2 0.2 0.29 12.0 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Pyr_redox_dim PF02852.17 EAQ91903.1 - 4.4e-27 94.3 0.0 8.4e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EAQ91903.1 - 8e-23 81.3 3.0 9.6e-22 77.8 2.1 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ91903.1 - 1.2e-20 73.7 0.1 4.7e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ91903.1 - 4.7e-05 23.5 0.0 0.017 15.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EAQ91903.1 - 0.00018 21.1 0.1 0.00048 19.8 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EAQ91903.1 - 0.001 19.0 0.6 0.1 12.6 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ91903.1 - 0.0058 15.5 10.3 0.049 12.5 0.2 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ91903.1 - 0.007 14.8 0.3 0.19 10.1 0.0 2.6 2 1 1 3 3 3 1 HI0933-like protein XdhC_C PF13478.1 EAQ91903.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 EAQ91903.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EAQ91903.1 - 0.036 12.9 0.1 0.24 10.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EAQ91903.1 - 0.045 13.9 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EAQ91903.1 - 0.049 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EAQ91903.1 - 0.07 12.2 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAQ91903.1 - 0.07 13.1 0.0 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.15 EAQ91903.1 - 0.12 12.3 0.3 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Dimer_Tnp_hAT PF05699.9 EAQ91904.1 - 3.9e-16 58.4 0.1 6.5e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glyoxalase_2 PF12681.2 EAQ91906.1 - 6.7e-07 29.8 0.3 8.2e-07 29.5 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EAQ91906.1 - 0.0029 17.5 0.0 0.0035 17.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DHFR_2 PF06442.6 EAQ91906.1 - 0.031 13.9 0.5 0.4 10.3 0.0 2.3 2 1 0 2 2 2 0 R67 dihydrofolate reductase DUF2580 PF10824.3 EAQ91906.1 - 4.8 7.5 7.4 4.6 7.6 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) SnoaL_4 PF13577.1 EAQ91907.1 - 1.1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain AA_permease PF00324.16 EAQ91908.1 - 7.2e-63 212.5 37.3 5.2e-59 199.8 15.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAQ91908.1 - 7.4e-19 67.5 25.9 7.4e-19 67.5 18.0 1.6 1 1 1 2 2 2 1 Amino acid permease DUF1772 PF08592.6 EAQ91908.1 - 0.0081 15.8 1.7 0.0081 15.8 1.2 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1772) Sugar_tr PF00083.19 EAQ91909.1 - 3.2e-89 299.5 20.7 3.9e-89 299.3 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ91909.1 - 2.1e-31 108.9 44.0 4.3e-25 88.1 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EAQ91909.1 - 0.059 13.4 1.6 0.62 10.1 0.7 2.6 2 0 0 2 2 2 0 Phage holin family 2 BTB PF00651.26 EAQ91910.1 - 1.8e-15 56.8 0.0 3.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Mid2 PF04478.7 EAQ91910.1 - 0.041 13.3 0.2 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor GFA PF04828.9 EAQ91911.1 - 1.4e-10 40.9 1.3 1.4e-10 40.9 0.9 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lig_chan PF00060.21 EAQ91913.1 - 0.45 10.2 2.8 3.7 7.2 1.1 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel Ank_2 PF12796.2 EAQ91914.1 - 1.7e-14 53.9 0.1 6.1e-06 26.4 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ91914.1 - 2.3e-12 46.0 0.5 0.041 13.7 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EAQ91914.1 - 1.4e-08 34.9 0.1 0.00027 21.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ91914.1 - 2.3e-07 30.8 2.1 0.00086 19.4 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91914.1 - 0.0017 18.4 0.8 3 8.3 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Clr5 PF14420.1 EAQ91914.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Clr5 domain RelA_SpoT PF04607.12 EAQ91917.1 - 1.9e-12 47.1 0.7 1.9e-11 44.0 0.5 2.5 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins APH PF01636.18 EAQ91918.1 - 1.1e-14 54.7 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ91918.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Methyltransf_2 PF00891.13 EAQ91919.1 - 1.1e-08 34.6 0.0 1.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Glyco_transf_20 PF00982.16 EAQ91920.1 - 6.7e-147 489.7 0.0 8.9e-147 489.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EAQ91920.1 - 3.2e-76 255.3 0.0 7.8e-76 254.0 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 EAQ91920.1 - 0.019 15.1 0.0 0.09 12.9 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EAQ91920.1 - 0.12 11.7 0.0 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 Cys_Met_Meta_PP PF01053.15 EAQ91923.1 - 8.6e-36 123.0 0.0 1.3e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CheW PF01584.14 EAQ91923.1 - 0.03 13.8 0.2 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 CheW-like domain Aminotran_1_2 PF00155.16 EAQ91923.1 - 0.068 12.1 0.0 0.15 10.9 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II PDE6_gamma PF04868.7 EAQ91923.1 - 0.12 12.2 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Claudin_2 PF13903.1 EAQ91926.1 - 0.00049 19.8 0.8 0.00062 19.5 0.6 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DZR PF12773.2 EAQ91926.1 - 0.002 17.9 1.5 0.0037 17.0 1.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EAQ91926.1 - 0.16 11.2 9.4 0.59 9.4 6.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EAQ91926.1 - 0.28 10.9 5.2 3.1 7.5 0.6 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.6 EAQ91926.1 - 0.55 9.7 10.7 3.6 7.1 1.4 3.3 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF805 PF05656.9 EAQ91926.1 - 1.2 9.0 7.8 13 5.6 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Tic20 PF09685.5 EAQ91926.1 - 1.6 8.7 6.1 0.2 11.6 1.4 1.5 2 0 0 2 2 2 0 Tic20-like protein zinc_ribbon_2 PF13240.1 EAQ91926.1 - 1.7 8.2 10.9 8.6 5.9 1.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Ank PF00023.25 EAQ91927.1 - 6.1e-07 28.9 3.6 0.0015 18.2 0.2 3.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EAQ91927.1 - 5.4e-06 26.6 0.0 2.4e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_16 PF13191.1 EAQ91927.1 - 8.2e-06 25.9 0.1 3.8e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Ank_5 PF13857.1 EAQ91927.1 - 2.4e-05 24.4 0.2 0.35 11.1 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ91927.1 - 0.0012 19.3 0.6 0.0075 16.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91927.1 - 0.0022 18.0 0.8 0.36 11.1 0.2 3.7 2 0 0 2 2 2 1 Ankyrin repeat AAA_14 PF13173.1 EAQ91927.1 - 0.026 14.4 0.0 9 6.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain Dscam_C PF12355.3 EAQ91927.1 - 0.18 12.1 0.8 0.32 11.2 0.6 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Ank_2 PF12796.2 EAQ91929.1 - 4.3e-56 187.2 0.0 3e-16 59.5 0.1 5.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ91929.1 - 4.1e-42 139.9 1.9 3.3e-06 26.6 0.0 10.3 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 EAQ91929.1 - 8.5e-39 130.7 5.6 3.5e-07 30.2 0.0 7.6 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ91929.1 - 1.5e-35 120.9 1.3 5.7e-08 33.0 0.0 6.7 2 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ91929.1 - 4.6e-35 116.1 0.1 5e-05 23.1 0.0 10.1 9 0 0 9 9 9 7 Ankyrin repeat NACHT PF05729.7 EAQ91929.1 - 3e-11 43.2 0.0 2.6e-09 36.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Arf PF00025.16 EAQ91929.1 - 5.7e-07 28.9 0.0 1.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EAQ91929.1 - 0.00022 21.3 2.3 0.0012 19.0 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 EAQ91929.1 - 0.00039 20.6 0.0 0.0017 18.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAQ91929.1 - 0.0025 17.8 0.2 0.1 12.5 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EAQ91929.1 - 0.0031 16.9 0.0 0.041 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAQ91929.1 - 0.0039 17.9 0.0 0.13 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EAQ91929.1 - 0.0088 15.0 0.0 0.035 13.0 0.0 1.8 2 0 0 2 2 2 1 KAP family P-loop domain AAA_18 PF13238.1 EAQ91929.1 - 0.011 15.9 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAQ91929.1 - 0.02 15.0 0.0 0.097 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EAQ91929.1 - 0.025 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EAQ91929.1 - 0.029 13.3 0.0 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 EAQ91929.1 - 0.037 13.6 0.0 0.51 9.9 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_tran PF00005.22 EAQ91929.1 - 0.042 14.1 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 EAQ91929.1 - 0.076 12.4 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EAQ91929.1 - 0.1 11.6 0.0 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 EAQ91929.1 - 0.13 12.2 0.1 1.2 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain Hemerythrin PF01814.18 EAQ91931.1 - 0.00055 20.1 0.3 0.0008 19.5 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CEP44 PF15007.1 EAQ91931.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 RVT_2 PF07727.9 EAQ91932.1 - 0.023 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Hemerythrin PF01814.18 EAQ91933.1 - 1.6e-05 25.1 0.6 2.7e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PTR2 PF00854.16 EAQ91934.1 - 1.3e-08 34.0 1.4 2.3e-08 33.2 0.1 2.0 1 1 2 3 3 3 1 POT family MFS_1 PF07690.11 EAQ91934.1 - 4.9e-06 25.4 7.1 0.013 14.2 3.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EAQ91934.1 - 0.03 13.0 0.1 0.03 13.0 0.1 1.9 2 0 0 2 2 2 0 Nucleoside H+ symporter LNP1 PF15419.1 EAQ91935.1 - 0.14 12.2 0.2 0.3 11.1 0.2 1.4 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 Methyltransf_31 PF13847.1 EAQ91936.1 - 1.2e-18 67.2 0.0 3.1e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ91936.1 - 1.2e-15 58.1 0.0 3.3e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ91936.1 - 7.1e-10 39.2 0.0 1.7e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ91936.1 - 6.9e-09 36.0 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91936.1 - 1.7e-08 34.3 0.0 3.3e-08 33.4 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAQ91936.1 - 4.8e-06 25.7 0.0 9.2e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EAQ91936.1 - 5.4e-06 26.7 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ91936.1 - 5.8e-06 25.7 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EAQ91936.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ91936.1 - 0.0003 19.9 0.0 0.00087 18.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EAQ91936.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EAQ91936.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EAQ91936.1 - 0.0025 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EAQ91936.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 EAQ91936.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EAQ91936.1 - 0.043 13.3 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ferric_reduct PF01794.14 EAQ91937.1 - 2e-16 60.2 18.6 2e-16 60.2 12.9 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EAQ91937.1 - 9.1e-07 28.8 0.1 0.0051 16.7 0.0 2.8 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAQ91937.1 - 3e-05 23.8 0.0 0.054 13.3 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EAQ91937.1 - 0.00028 21.4 0.0 0.00095 19.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4293 PF14126.1 EAQ91937.1 - 1.6 8.6 6.6 0.31 10.9 0.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) ATP-grasp_4 PF13535.1 EAQ91938.1 - 2.6e-20 72.9 0.0 2.8e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EAQ91938.1 - 3.4e-05 22.7 0.0 0.095 11.4 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EAQ91938.1 - 0.0027 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EAQ91938.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain MULE PF10551.4 EAQ91940.1 - 3.7e-18 65.4 0.1 8.3e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ91940.1 - 2.8e-08 32.7 0.2 8e-08 31.2 0.0 1.8 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 EAQ91940.1 - 0.0005 20.5 0.1 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain rve PF00665.21 EAQ91941.1 - 1e-18 67.5 0.4 2.9e-18 66.1 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EAQ91941.1 - 1.8e-11 43.4 0.2 1.8e-11 43.4 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EAQ91941.1 - 5.1e-05 22.5 0.0 0.00011 21.4 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger PALP PF00291.20 EAQ91942.1 - 2.8e-08 33.3 0.0 9e-08 31.6 0.0 2.0 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Mito_carr PF00153.22 EAQ91943.1 - 1e-54 182.1 5.6 3.1e-22 78.0 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.4 EAQ91945.1 - 5.7e-56 189.4 2.5 1.8e-27 96.2 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF2370) PCMT PF01135.14 EAQ91946.1 - 7e-53 179.2 0.0 8.4e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EAQ91946.1 - 5.8e-06 26.8 0.0 8.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ91946.1 - 3.6e-05 23.4 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAQ91946.1 - 0.00021 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ91946.1 - 0.00036 20.5 0.1 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ91946.1 - 0.0021 17.8 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ91946.1 - 0.017 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EAQ91946.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.14 EAQ91947.1 - 1.9e-10 40.3 0.0 6.5e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ91947.1 - 6.1e-06 25.3 0.1 1.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ91947.1 - 7.4e-06 26.2 2.2 7.6e-06 26.2 0.1 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ91947.1 - 5.6e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ91947.1 - 0.00086 18.2 0.1 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ91947.1 - 0.00095 19.0 0.2 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ91947.1 - 0.0016 17.5 0.3 0.0027 16.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ91947.1 - 0.0029 16.7 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 EAQ91947.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EAQ91947.1 - 0.007 15.2 0.9 0.015 14.2 0.4 1.6 1 1 1 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EAQ91947.1 - 0.057 13.4 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EAQ91947.1 - 0.096 12.2 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EAQ91947.1 - 0.21 11.2 0.3 0.32 10.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EAQ91948.1 - 1.9e-16 59.7 0.8 2.7e-16 59.2 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ91948.1 - 1.8e-10 40.5 10.6 3.6e-10 39.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MucB_RseB PF03888.9 EAQ91948.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB family RVT_1 PF00078.22 EAQ91949.1 - 3.2e-30 105.1 0.0 4.6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EAQ91950.1 - 5.6e-60 202.3 0.0 9.3e-60 201.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91950.1 - 4.8e-17 62.1 0.0 1.4e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ91950.1 - 0.022 14.3 0.1 0.053 13.1 0.1 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain RVP PF00077.15 EAQ91950.1 - 0.051 13.4 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease UBN2 PF14223.1 EAQ91950.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_AsnC-type PF13404.1 EAQ91950.1 - 0.17 11.4 0.0 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF2841 PF11001.3 EAQ91951.1 - 8.5e-31 106.4 0.0 1.1e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) S-antigen PF05756.6 EAQ91954.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 S-antigen protein Dimer_Tnp_hAT PF05699.9 EAQ91955.1 - 8.9e-18 63.7 0.2 1.4e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CcoS PF03597.10 EAQ91957.1 - 0.047 13.1 0.7 0.11 11.9 0.5 1.7 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type CVNH PF08881.5 EAQ91958.1 - 4e-13 49.4 0.9 6.1e-12 45.6 0.5 2.0 1 1 1 2 2 2 2 CVNH domain Reo_sigmaC PF04582.7 EAQ91960.1 - 1.1e-05 24.7 56.3 0.0022 17.2 1.6 5.8 2 1 5 7 7 7 7 Reovirus sigma C capsid protein IncA PF04156.9 EAQ91960.1 - 0.0031 17.1 20.2 0.0031 17.1 14.0 7.7 2 2 5 7 7 7 6 IncA protein DUF4201 PF13870.1 EAQ91960.1 - 0.0047 16.3 5.5 0.0047 16.3 3.8 8.0 2 2 6 8 8 8 2 Domain of unknown function (DUF4201) AAA_13 PF13166.1 EAQ91960.1 - 0.012 14.1 82.7 0.023 13.1 15.6 4.5 2 1 1 4 4 4 0 AAA domain Filament PF00038.16 EAQ91960.1 - 0.031 13.7 106.3 0.025 14.0 10.5 7.7 2 2 4 6 6 6 0 Intermediate filament protein Myosin_tail_1 PF01576.14 EAQ91960.1 - 3.6 5.2 119.2 0.0096 13.7 53.9 3.2 2 2 1 3 3 3 0 Myosin tail DAO PF01266.19 EAQ91961.1 - 8e-41 140.1 4.1 9.7e-41 139.8 2.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EAQ91961.1 - 1.4e-12 47.0 0.2 3.2e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 EAQ91961.1 - 6.5e-07 29.2 0.6 1.8e-06 27.8 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ91961.1 - 0.0004 19.3 0.3 0.00065 18.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EAQ91961.1 - 0.00074 18.7 4.5 0.0088 15.1 1.9 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ91961.1 - 0.0024 18.2 0.2 0.0089 16.4 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ91961.1 - 0.0046 16.8 0.2 0.023 14.5 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ91961.1 - 0.0049 16.9 0.9 0.1 12.6 0.6 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ91961.1 - 0.012 14.6 1.9 0.018 14.1 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EAQ91961.1 - 0.013 14.0 0.1 0.018 13.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EAQ91961.1 - 0.016 14.8 0.2 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EAQ91961.1 - 0.022 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 EAQ91961.1 - 0.06 12.4 0.3 0.21 10.5 0.2 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EAQ91961.1 - 0.089 11.6 1.2 0.16 10.8 0.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EAQ91961.1 - 0.095 11.5 0.5 0.34 9.7 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 EAQ91962.1 - 1.1e-16 61.1 13.0 1.6e-15 57.4 9.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ91962.1 - 1.9e-09 37.6 0.1 1.8e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ91962.1 - 7.7e-08 32.2 0.9 7.7e-08 32.2 0.6 2.0 2 0 0 2 2 2 1 KR domain RNase_H PF00075.19 EAQ91963.1 - 2.9e-15 56.7 0.0 6.7e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.13 EAQ91963.1 - 1.5e-08 34.3 6.2 2.9e-08 33.4 4.3 1.5 1 0 0 1 1 1 1 MYND finger RVT_3 PF13456.1 EAQ91963.1 - 0.00027 20.6 0.0 0.0052 16.5 0.0 2.5 1 1 0 1 1 1 1 Reverse transcriptase-like RTA1 PF04479.8 EAQ91964.1 - 0.00079 18.9 0.5 0.0012 18.4 0.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Exo_endo_phos_2 PF14529.1 EAQ91966.1 - 3.1e-23 81.6 0.0 1.7e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ91966.1 - 2.1e-09 37.6 0.1 3e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EAQ91966.1 - 0.0017 18.2 3.5 0.0036 17.1 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Dimer_Tnp_hAT PF05699.9 EAQ91969.1 - 3.3e-17 61.8 0.2 7.5e-17 60.7 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4174 PF13778.1 EAQ91970.1 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) WHG PF13305.1 EAQ91970.1 - 0.06 13.9 0.6 0.62 10.6 0.0 2.7 2 1 0 2 2 2 0 WHG domain DDE_1 PF03184.14 EAQ91971.1 - 1.1e-18 67.2 0.1 2.2e-15 56.3 0.0 3.2 4 0 0 4 4 4 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ91971.1 - 4.4e-14 52.0 0.1 9.3e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MULE PF10551.4 EAQ91972.1 - 0.0008 19.5 1.9 0.013 15.5 1.3 2.7 1 1 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ91972.1 - 0.0052 17.2 0.1 0.014 15.9 0.1 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain p450 PF00067.17 EAQ91973.1 - 1.5e-43 149.0 0.0 1.9e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 rve PF00665.21 EAQ91974.1 - 2.8e-17 62.9 0.0 1.1e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EAQ91974.1 - 1.8e-13 50.3 0.0 4.7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EAQ91974.1 - 5.5e-07 29.1 0.5 1.8e-06 27.4 0.3 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EAQ91974.1 - 0.00014 21.6 2.3 0.0004 20.1 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EAQ91974.1 - 0.0037 17.2 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EAQ91974.1 - 0.023 14.7 0.1 0.023 14.7 0.1 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein gag-asp_proteas PF13975.1 EAQ91974.1 - 0.032 14.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF501 PF04417.7 EAQ91974.1 - 0.14 12.0 1.0 0.38 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF972 PF06156.8 EAQ91974.1 - 0.17 12.2 3.5 0.58 10.5 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nup88 PF10168.4 EAQ91974.1 - 0.29 8.9 2.4 0.47 8.2 1.7 1.2 1 0 0 1 1 1 0 Nuclear pore component Atg14 PF10186.4 EAQ91974.1 - 0.3 9.9 2.8 0.64 8.9 1.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MMS22L_C PF14911.1 EAQ91974.1 - 0.65 8.9 1.3 1.3 8.0 0.9 1.4 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Exo_endo_phos_2 PF14529.1 EAQ91975.1 - 3.7e-07 29.7 2.4 6.5e-06 25.7 0.4 3.2 4 0 0 4 4 4 1 Endonuclease-reverse transcriptase SlyX PF04102.7 EAQ91975.1 - 0.0012 19.1 4.0 0.028 14.7 0.6 2.6 1 1 1 2 2 2 2 SlyX zf-CCHC PF00098.18 EAQ91975.1 - 0.0054 16.6 2.4 0.0054 16.6 1.6 2.9 3 0 0 3 3 3 1 Zinc knuckle SEEK1 PF15357.1 EAQ91975.1 - 0.051 13.4 0.8 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 USP8_interact PF08941.5 EAQ91975.1 - 0.054 12.8 0.2 0.13 11.5 0.1 1.7 2 0 0 2 2 2 0 USP8 interacting Filament PF00038.16 EAQ91975.1 - 0.62 9.4 4.6 0.34 10.3 0.7 2.1 2 0 0 2 2 2 0 Intermediate filament protein Mid2 PF04478.7 EAQ91977.1 - 0.047 13.1 0.2 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HET PF06985.6 EAQ91979.1 - 1.4e-27 96.5 0.2 2.9e-27 95.5 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 EAQ91980.1 - 2.8e-07 29.9 1.3 5.5e-07 29.0 0.9 1.5 1 0 0 1 1 1 1 Subtilase family RVT_2 PF07727.9 EAQ91982.1 - 2.3e-15 56.2 0.2 1.3e-08 34.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ91982.1 - 1.4e-11 44.5 0.0 3.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ91982.1 - 6.8e-07 28.8 0.0 2.3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_1 PF00078.22 EAQ91984.1 - 8.3e-31 107.0 0.0 1.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ91984.1 - 4.4e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ91984.1 - 2e-05 24.6 0.2 6.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EAQ91984.1 - 0.031 14.5 0.2 0.12 12.7 0.2 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF4066 PF13278.1 EAQ91985.1 - 1.1e-23 83.3 0.0 1.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ91985.1 - 4e-13 49.0 0.0 5.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_6 PF12697.2 EAQ91986.1 - 2.1e-08 34.3 0.1 6.7e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ91986.1 - 2.3e-07 30.6 0.0 5.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 EAQ91986.1 - 3.6e-07 29.9 0.0 8.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EAQ91986.1 - 1.4e-06 27.7 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 EAQ91986.1 - 3.2e-05 23.9 0.0 0.0001 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_5 PF12695.2 EAQ91986.1 - 0.00049 19.8 0.2 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EAQ91986.1 - 0.0014 18.7 0.0 0.22 11.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF3312 PF11768.3 EAQ91986.1 - 0.0015 16.8 0.0 0.0032 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) DUF2075 PF09848.4 EAQ91986.1 - 0.0066 15.4 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EAQ91986.1 - 0.019 13.8 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Lipase_3 PF01764.20 EAQ91986.1 - 0.035 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 EAQ91986.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EAQ91986.1 - 0.12 12.0 0.0 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Cutinase AAA_5 PF07728.9 EAQ91986.1 - 0.17 11.6 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) LCAT PF02450.10 EAQ91986.1 - 0.23 10.3 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase RNA_helicase PF00910.17 EAQ91986.1 - 0.25 11.5 0.0 0.55 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EAQ91986.1 - 0.26 10.9 0.0 0.51 9.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Fructosamin_kin PF03881.9 EAQ91987.1 - 2e-38 131.9 0.0 2.7e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAQ91987.1 - 0.00022 21.0 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_61 PF03443.9 EAQ91988.1 - 2.2e-24 86.5 0.0 2.7e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pectate_lyase_3 PF12708.2 EAQ91989.1 - 1.9e-32 113.2 6.1 4.4e-20 72.7 2.3 2.9 3 1 0 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.1 EAQ91989.1 - 0.00091 19.0 2.0 0.0028 17.4 1.4 1.8 1 0 0 1 1 1 1 Right handed beta helix region Fungal_trans PF04082.13 EAQ91993.1 - 0.0057 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SnoaL_4 PF13577.1 EAQ91994.1 - 5.1e-15 55.4 0.4 6.7e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain RPE65 PF03055.10 EAQ91995.1 - 1e-132 443.1 0.0 1.2e-132 442.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein HET PF06985.6 EAQ91996.1 - 6.7e-18 65.1 0.0 9.7e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NPDC1 PF06809.6 EAQ91996.1 - 0.016 14.0 0.3 0.031 13.0 0.0 1.6 2 0 0 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) Amidohydro_5 PF13594.1 EAQ91996.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase DUF2421 PF10334.4 EAQ91996.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF3716 PF12511.3 EAQ91996.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) p450 PF00067.17 EAQ91997.1 - 0.12 10.9 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P450 Ank_2 PF12796.2 EAQ91998.1 - 1.6e-53 179.0 2.8 2.7e-15 56.4 0.3 5.3 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ91998.1 - 2.8e-40 134.1 15.6 1.7e-08 33.8 0.1 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 EAQ91998.1 - 1.3e-32 108.5 0.5 2.8e-05 23.9 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EAQ91998.1 - 1.3e-31 107.8 7.2 2e-10 40.5 0.1 7.1 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ91998.1 - 2.7e-28 97.8 1.6 2.5e-08 34.2 0.0 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Cation_ATPase_C PF00689.16 EAQ91998.1 - 0.47 9.9 2.3 11 5.5 0.0 2.8 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus RVT_1 PF00078.22 EAQ92000.1 - 1.8e-18 66.6 0.0 3.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ92000.1 - 3.9e-18 65.6 0.0 1.2e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EAQ92000.1 - 9.7e-07 28.3 0.5 2.7e-06 26.9 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EAQ92000.1 - 8.7e-05 22.2 1.8 0.0002 21.1 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EAQ92000.1 - 0.00051 19.9 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EAQ92000.1 - 0.016 15.2 0.2 0.18 11.9 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein UBN2 PF14223.1 EAQ92001.1 - 0.002 17.9 0.1 0.0049 16.6 0.1 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EAQ92001.1 - 0.019 14.5 0.6 0.063 12.8 0.0 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DNA_Packaging PF11053.3 EAQ92001.1 - 0.036 13.6 1.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Terminase DNA packaging enzyme DUF3994 PF13159.1 EAQ92001.1 - 0.19 12.0 8.1 0.97 9.7 2.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3994) DUF4284 PF14112.1 EAQ92001.1 - 0.64 10.5 4.8 0.15 12.5 0.5 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4284) DUF3237 PF11578.3 EAQ92003.1 - 1.3e-28 99.2 0.0 1.5e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) adh_short PF00106.20 EAQ92004.1 - 8.8e-19 68.0 1.1 1.2e-18 67.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ92004.1 - 2.9e-09 37.0 0.0 0.00045 20.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ92004.1 - 3.8e-08 33.1 0.4 5.5e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EAQ92004.1 - 0.0046 16.7 0.1 0.011 15.5 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EAQ92004.1 - 0.03 14.1 1.4 0.079 12.7 1.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EAQ92004.1 - 0.12 11.4 0.3 0.2 10.7 0.2 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 EAQ92005.1 - 1.2e-62 212.0 0.0 1.5e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_q1 PF00361.15 EAQ92006.1 - 0.00085 18.6 1.6 0.069 12.4 1.1 2.6 1 1 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains FAD_binding_3 PF01494.14 EAQ92008.1 - 6.7e-25 87.8 0.0 1.2e-24 87.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAQ92008.1 - 7.7e-06 25.0 0.9 4.6e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EAQ92008.1 - 6.2e-05 22.2 0.1 0.047 12.7 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ92008.1 - 0.00014 21.8 1.7 0.00027 20.8 0.4 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EAQ92008.1 - 0.00018 21.0 0.1 0.00041 19.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EAQ92008.1 - 0.00076 19.5 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAQ92008.1 - 0.0037 16.1 1.8 0.0037 16.1 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EAQ92008.1 - 0.0083 15.2 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EAQ92008.1 - 0.022 15.1 2.3 0.1 13.0 0.5 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ92008.1 - 0.041 13.7 0.3 0.078 12.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase B12-binding PF02310.14 EAQ92008.1 - 0.098 12.5 0.2 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain MFS_1 PF07690.11 EAQ92009.1 - 3.3e-34 118.1 55.2 1.6e-24 86.2 17.2 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Ost4 PF10215.4 EAQ92009.1 - 0.15 11.5 2.5 0.32 10.5 0.3 2.7 2 0 0 2 2 2 0 Oligosaccaryltransferase Pyr_redox_3 PF13738.1 EAQ92010.1 - 2.6e-25 89.7 0.0 1e-22 81.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ92010.1 - 5.2e-12 45.3 0.0 2.7e-10 39.6 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EAQ92010.1 - 2.3e-08 32.7 0.0 0.00067 17.9 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EAQ92010.1 - 0.00054 19.7 0.1 0.41 10.4 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EAQ92010.1 - 0.069 12.2 0.1 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ketoacyl-synt PF00109.21 EAQ92011.1 - 8e-66 222.0 0.0 1.5e-65 221.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EAQ92011.1 - 1.9e-59 200.3 1.5 8.4e-59 198.2 0.6 2.6 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EAQ92011.1 - 1.3e-48 165.0 1.2 1.3e-48 165.0 0.8 3.5 3 0 0 3 3 3 1 short chain dehydrogenase DUF4267 PF14087.1 EAQ92011.1 - 4e-30 103.7 2.4 4e-30 103.7 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4267) Ketoacyl-synt_C PF02801.17 EAQ92011.1 - 1.8e-29 102.0 1.8 3.5e-29 101.0 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EAQ92011.1 - 1.4e-25 90.0 1.1 1.6e-11 43.9 0.0 3.7 2 1 1 3 3 3 3 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EAQ92011.1 - 5.5e-08 32.5 2.6 8.5e-05 22.0 0.5 3.0 2 1 1 3 3 3 2 Acyl transferase domain ADH_N PF08240.7 EAQ92011.1 - 2.3e-06 27.3 0.5 5.9e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EAQ92011.1 - 9.1e-05 22.6 0.1 0.0013 18.9 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EAQ92011.1 - 0.00077 18.5 0.2 0.00077 18.5 0.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EAQ92011.1 - 0.022 14.3 1.7 0.19 11.4 1.2 2.7 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acyl_transf_3 PF01757.17 EAQ92011.1 - 0.4 9.4 1.6 0.65 8.7 1.1 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF320 PF03777.8 EAQ92012.1 - 0.2 11.4 1.6 0.22 11.3 1.1 1.2 1 0 0 1 1 1 0 Small secreted domain (DUF320) DUF2184 PF09950.4 EAQ92017.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) RVT_2 PF07727.9 EAQ92018.1 - 5.5e-50 169.6 0.0 3.8e-49 166.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EAQ92018.1 - 1.3e-11 44.6 0.0 4e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EAQ92018.1 - 1.4e-06 27.8 0.0 2.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3237 PF11578.3 EAQ92020.1 - 9.9e-29 99.5 0.0 2.1e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.13 EAQ92020.1 - 3.7e-10 39.5 9.0 3.7e-10 39.5 6.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ92020.1 - 0.00055 18.8 0.1 0.00097 18.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SKG6 PF08693.5 EAQ92022.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2681 PF10883.3 EAQ92022.1 - 0.028 14.6 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) P12 PF12669.2 EAQ92022.1 - 0.8 9.9 7.6 0.82 9.9 0.1 2.9 2 0 0 2 2 2 0 Virus attachment protein p12 family Gly_transf_sug PF04488.10 EAQ92023.1 - 4.4e-06 27.0 0.0 1.6e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Beta-lactamase PF00144.19 EAQ92024.1 - 5.1e-26 91.4 1.3 7.9e-26 90.8 0.9 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2235 PF09994.4 EAQ92025.1 - 3.2e-23 82.4 2.6 3.3e-13 49.6 0.6 2.1 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) p450 PF00067.17 EAQ92026.1 - 9e-57 192.6 0.0 1.1e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.3 EAQ92028.1 - 4e-33 113.5 1.2 7.5e-33 112.7 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF202 PF02656.10 EAQ92028.1 - 2 8.6 0.0 2 8.6 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Chitin_bind_3 PF03067.10 EAQ92029.1 - 7.3e-06 26.3 0.1 9.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain adh_short PF00106.20 EAQ92030.1 - 3.8e-21 75.7 1.0 7.1e-21 74.8 0.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ92030.1 - 1.6e-11 44.4 0.0 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ92030.1 - 0.00044 20.2 0.1 0.00084 19.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAQ92030.1 - 0.0011 18.4 0.1 0.0019 17.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EAQ92030.1 - 0.01 15.5 0.5 0.03 13.9 0.3 1.8 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 EAQ92030.1 - 0.024 14.4 0.1 0.07 12.9 0.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EAQ92030.1 - 0.034 13.2 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EAQ92030.1 - 0.095 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Mac PF12464.3 EAQ92031.1 - 6.4e-19 67.7 0.0 1.1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.11 EAQ92031.1 - 2.5e-18 65.9 53.4 5.2e-10 38.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexapep PF00132.19 EAQ92031.1 - 1.7e-13 49.3 8.7 1e-11 43.7 4.0 3.5 4 0 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAQ92031.1 - 7.5e-12 44.6 9.9 6.3e-11 41.6 3.3 3.6 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF1228 PF06779.9 EAQ92031.1 - 0.00014 21.8 10.2 0.11 12.4 0.1 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Pectate_lyase PF03211.8 EAQ92032.1 - 3.7e-68 229.1 2.5 5.6e-68 228.5 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase DUF605 PF04652.11 EAQ92033.1 - 0.19 11.1 2.9 0.24 10.7 2.0 1.1 1 0 0 1 1 1 0 Vta1 like UvrD_C_2 PF13538.1 EAQ92034.1 - 0.00039 20.5 0.0 0.001 19.1 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAQ92034.1 - 0.00094 17.0 0.0 0.0013 16.6 0.0 1.1 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EAQ92034.1 - 0.015 14.2 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase adh_short PF00106.20 EAQ92035.1 - 2.6e-09 37.1 1.4 5.9e-09 36.0 0.1 2.2 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EAQ92035.1 - 9.1e-06 25.4 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ92035.1 - 6.2e-05 22.5 0.0 8.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAQ92035.1 - 0.0018 17.2 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Transp_cyt_pur PF02133.10 EAQ92035.1 - 0.076 11.5 0.1 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin zf-C2H2_6 PF13912.1 EAQ92036.1 - 0.023 14.6 0.1 0.023 14.6 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ92036.1 - 1.4 9.3 3.6 0.7 10.3 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type SET PF00856.23 EAQ92037.1 - 3e-12 47.1 0.0 1.1e-11 45.3 0.0 1.9 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 EAQ92037.1 - 4.7e-11 42.1 11.0 2.9e-08 33.2 3.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAQ92037.1 - 6e-06 25.7 10.8 0.0029 17.3 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ92037.1 - 0.089 12.4 12.0 0.86 9.3 1.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ92037.1 - 0.38 10.7 11.3 0.75 9.7 4.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ92037.1 - 0.8 10.5 13.7 0.15 12.7 0.6 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ92037.1 - 2.4 8.9 16.7 0.17 12.5 1.1 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 EAQ92038.1 - 2.5e-47 159.1 3.6 4.1e-19 68.7 0.2 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ92038.1 - 1.2e-36 122.7 12.8 3.9e-08 32.6 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat AA_permease_2 PF13520.1 EAQ92038.1 - 1.8e-31 109.1 34.1 4.3e-31 107.8 23.6 1.6 1 0 0 1 1 1 1 Amino acid permease Ank_5 PF13857.1 EAQ92038.1 - 1.3e-27 95.1 3.4 2.8e-08 33.7 0.1 5.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92038.1 - 3.3e-24 82.5 4.3 7.7e-06 25.6 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EAQ92038.1 - 7.4e-21 74.1 3.9 7.4e-05 23.1 0.1 6.3 3 1 4 7 7 7 6 Ankyrin repeats (many copies) AA_permease PF00324.16 EAQ92038.1 - 1e-05 24.1 28.1 1.9e-05 23.1 19.5 1.4 1 0 0 1 1 1 1 Amino acid permease DUF35 PF01796.12 EAQ92040.1 - 0.24 11.6 1.3 12 6.1 0.1 2.5 2 0 0 2 2 2 0 DUF35 OB-fold domain Methyltransf_6 PF03737.10 EAQ92041.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase DUF3042 PF11240.3 EAQ92042.1 - 0.36 10.6 0.1 0.36 10.6 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3042) DUF4044 PF13253.1 EAQ92042.1 - 7.9 5.7 7.1 3 7.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Pyr_redox_2 PF07992.9 EAQ92044.1 - 8.6e-07 29.0 0.0 2.3e-05 24.3 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ92044.1 - 0.0002 21.2 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EAQ92044.1 - 0.0022 16.9 0.2 0.0079 15.1 0.1 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ92044.1 - 0.03 14.4 0.1 0.076 13.0 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EAQ92044.1 - 0.12 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Piwi PF02171.12 EAQ92045.1 - 3.2e-58 197.0 0.0 2.1e-57 194.3 0.0 2.0 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EAQ92045.1 - 1.9e-07 30.3 0.0 5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EAQ92045.1 - 0.0012 18.2 0.0 0.0051 16.1 0.0 2.1 2 0 0 2 2 2 1 PAZ domain DUF3005 PF11448.3 EAQ92045.1 - 0.077 12.6 0.2 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) AAA_26 PF13500.1 EAQ92048.1 - 9.2e-24 84.1 0.0 2.4e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.16 EAQ92049.1 - 4.3e-23 81.8 0.0 1.9e-17 63.2 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.15 EAQ92049.1 - 0.13 10.7 0.0 0.25 9.8 0.0 1.5 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Ada_Zn_binding PF02805.11 EAQ92051.1 - 1e-28 98.7 4.9 2e-28 97.7 3.4 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EAQ92051.1 - 3.3e-08 33.0 0.0 1.1e-07 31.4 0.0 1.9 1 1 1 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EAQ92051.1 - 1.7e-05 24.8 0.5 3.5e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Epimerase PF01370.16 EAQ92052.1 - 3e-11 43.2 1.0 9.8e-10 38.2 0.1 2.8 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAQ92052.1 - 9e-06 25.7 0.1 0.016 15.0 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EAQ92052.1 - 2.3e-05 24.5 0.1 6.5e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ92052.1 - 0.00022 20.0 0.0 0.064 11.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EAQ92052.1 - 0.00043 20.0 0.1 0.069 12.8 0.0 2.3 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.7 EAQ92052.1 - 0.00081 18.3 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Pkinase PF00069.20 EAQ92053.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Plant_zn_clust PF10533.4 EAQ92053.1 - 0.23 11.1 4.9 1 9.0 3.4 2.1 1 0 0 1 1 1 0 Plant zinc cluster domain DUF1996 PF09362.5 EAQ92054.1 - 1.9e-82 276.4 3.2 2.3e-82 276.1 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ADH_zinc_N PF00107.21 EAQ92055.1 - 2.9e-20 72.1 0.1 4.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ92055.1 - 2.3e-07 31.7 0.1 4.9e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CFEM PF05730.6 EAQ92056.1 - 1e-22 79.7 46.4 2.5e-11 43.2 6.7 4.5 4 1 1 5 5 5 3 CFEM domain zf-Sec23_Sec24 PF04810.10 EAQ92058.1 - 0.16 11.5 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Glyco_tranf_2_4 PF13704.1 EAQ92059.1 - 0.018 15.3 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 RRM_6 PF14259.1 EAQ92060.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3638 PF12340.3 EAQ92064.1 - 3.7e-95 317.2 0.0 6.6e-95 316.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EAQ92064.1 - 1.9e-15 55.6 0.1 4.1e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DEAD PF00270.24 EAQ92064.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase RVT_2 PF07727.9 EAQ92065.1 - 3.5e-18 65.4 0.3 8.2e-09 34.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EAQ92065.1 - 1.2e-06 28.0 0.0 4.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 EAQ92065.1 - 7.1e-06 26.1 0.1 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Glyco_hydro_18 PF00704.23 EAQ92067.1 - 2.2e-62 211.4 0.7 2.8e-62 211.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EAQ92067.1 - 2.3e-05 24.2 35.5 0.013 15.5 11.6 2.7 2 0 0 2 2 2 2 Chitin recognition protein Caleosin PF05042.8 EAQ92068.1 - 2.7e-50 170.3 0.0 3.8e-46 156.8 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein EF-hand_6 PF13405.1 EAQ92068.1 - 3.2e-05 23.4 0.3 0.19 11.7 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EAQ92068.1 - 0.00053 19.1 0.3 5.2 6.6 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 EAQ92068.1 - 0.0018 17.5 2.2 4.4 6.8 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EAQ92068.1 - 0.0044 17.1 0.0 0.15 12.2 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain pair Glyco_hydro_10 PF00331.15 EAQ92069.1 - 1.6e-106 355.9 0.5 1.9e-106 355.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EAQ92069.1 - 2.3e-14 52.7 10.1 2.3e-14 52.7 7.0 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.10 EAQ92069.1 - 0.0031 16.6 0.2 0.02 13.9 0.0 1.9 1 1 1 2 2 2 1 Beta-galactosidase YaaC PF14175.1 EAQ92069.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 YaaC-like Protein Glyco_hydro_2 PF00703.16 EAQ92070.1 - 6.2e-11 42.7 1.4 2.6e-10 40.7 0.1 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EAQ92070.1 - 7.4e-09 35.3 0.1 1.4e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain tRNA-synt_2 PF00152.15 EAQ92070.1 - 0.27 9.9 0.0 0.46 9.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) PIF1 PF05970.9 EAQ92071.1 - 3.8e-19 68.8 0.1 6.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ92071.1 - 3.7e-06 26.6 0.2 8.5e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ92071.1 - 0.0004 20.4 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RVT_1 PF00078.22 EAQ92072.1 - 1.7e-28 99.4 0.0 3.5e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ92072.1 - 2.4e-21 75.5 0.0 7e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ92072.1 - 4.4e-09 36.6 0.1 9e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Alpha_E1_glycop PF01589.11 EAQ92072.1 - 0.011 14.0 0.1 2.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Alphavirus E1 glycoprotein zf-RVT PF13966.1 EAQ92072.1 - 0.011 15.9 0.1 0.091 13.0 0.0 2.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Atg14 PF10186.4 EAQ92072.1 - 0.069 12.0 6.4 0.15 11.0 4.0 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 EAQ92072.1 - 0.87 9.4 4.2 2.9 7.6 2.9 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EAQ92072.1 - 2.8 5.3 4.9 4.9 4.5 3.4 1.3 1 0 0 1 1 1 0 Prominin UvrD_C_2 PF13538.1 EAQ92073.1 - 0.0052 16.9 0.0 0.021 14.9 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EAQ92075.1 - 9.6e-13 48.1 0.7 3.9e-08 32.9 0.0 2.6 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EAQ92075.1 - 4.8e-10 39.5 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EAQ92075.1 - 2.9e-05 23.7 0.1 7.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 EAQ92075.1 - 0.00021 20.8 0.0 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAQ92075.1 - 0.00026 21.1 0.0 0.00072 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EAQ92075.1 - 0.0006 19.3 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EAQ92075.1 - 0.00077 19.0 0.1 1.1 8.7 0.0 3.5 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EAQ92075.1 - 0.0053 16.3 0.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EAQ92075.1 - 0.014 14.7 0.0 0.066 12.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAQ92075.1 - 0.077 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MULE PF10551.4 EAQ92076.1 - 3.5e-11 43.1 0.0 6.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ92076.1 - 5.6e-05 23.5 0.7 0.00014 22.3 0.5 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain AT_hook PF02178.14 EAQ92076.1 - 0.13 11.9 8.8 0.37 10.6 3.0 3.1 2 0 0 2 2 2 0 AT hook motif ADP_ribosyl_GH PF03747.9 EAQ92077.1 - 5.4e-63 213.4 1.5 6.7e-63 213.1 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CHAT PF12770.2 EAQ92078.1 - 4.5e-26 91.6 0.0 2e-25 89.5 0.0 2.0 1 1 0 1 1 1 1 CHAT domain Peptidase_C14 PF00656.17 EAQ92081.1 - 2.1e-15 57.1 0.0 3.1e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Mac PF12464.3 EAQ92083.1 - 2.4e-10 40.2 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Peroxidase_2 PF01328.12 EAQ92084.1 - 9.4e-32 109.9 3.1 2.1e-18 66.0 0.1 2.0 1 1 1 2 2 2 2 Peroxidase, family 2 VWA_2 PF13519.1 EAQ92084.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain NAD_binding_8 PF13450.1 EAQ92087.1 - 2.8e-12 46.4 0.2 8e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAQ92087.1 - 3.6e-05 22.7 0.3 6.6e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EAQ92087.1 - 5.3e-05 22.2 0.3 7.5e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EAQ92087.1 - 6.5e-05 21.9 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAQ92087.1 - 7.1e-05 21.4 0.1 0.00012 20.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EAQ92087.1 - 0.00024 21.2 0.2 0.0005 20.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ92087.1 - 0.00026 20.1 0.1 0.00046 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EAQ92087.1 - 0.00029 20.7 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ92087.1 - 0.00073 18.6 0.4 0.0014 17.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EAQ92087.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EAQ92087.1 - 0.002 17.2 0.2 0.0032 16.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EAQ92087.1 - 0.016 13.8 0.2 0.029 13.0 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EAQ92087.1 - 0.052 13.9 0.0 0.27 11.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.2 EAQ92088.1 - 5.2e-44 148.5 1.3 1.8e-19 69.8 0.3 4.2 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ92088.1 - 3.4e-28 96.0 12.1 0.00021 20.9 0.1 7.9 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EAQ92088.1 - 3e-21 75.3 0.1 5.7e-07 29.8 0.0 6.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92088.1 - 2.7e-20 70.4 4.9 0.01 15.9 0.0 8.2 7 1 1 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EAQ92088.1 - 1.2e-17 63.4 6.4 0.0012 19.0 0.1 7.0 4 2 3 7 7 7 4 Ankyrin repeats (many copies) NACHT PF05729.7 EAQ92088.1 - 5e-07 29.5 0.0 9.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Patatin PF01734.17 EAQ92088.1 - 3.5e-06 27.0 0.0 7.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.1 EAQ92088.1 - 1.3e-05 25.2 0.0 4.8e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain ATP-synt_ab PF00006.20 EAQ92088.1 - 0.0034 16.8 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EAQ92088.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EAQ92088.1 - 0.012 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 EAQ92088.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 EAQ92088.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ92088.1 - 0.023 13.5 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 EAQ92088.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EAQ92088.1 - 0.033 14.4 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EAQ92088.1 - 0.035 14.2 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.15 EAQ92088.1 - 0.044 12.4 0.2 0.076 11.6 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit KAP_NTPase PF07693.9 EAQ92088.1 - 0.084 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF258 PF03193.11 EAQ92088.1 - 0.09 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UvrD-helicase PF00580.16 EAQ92088.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.1 EAQ92088.1 - 0.21 11.1 0.1 0.53 9.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aminotran_3 PF00202.16 EAQ92094.1 - 2.7e-32 111.9 0.3 1.6e-31 109.4 0.2 1.9 1 1 0 1 1 1 1 Aminotransferase class-III SR-25 PF10500.4 EAQ92095.1 - 1.5 8.2 7.3 1.6 8.1 5.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 EAQ92097.1 - 2.8e-12 45.9 7.6 0.001 18.8 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EAQ92097.1 - 0.15 10.1 0.0 0.26 9.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PH PF00169.24 EAQ92098.1 - 3.2e-14 52.9 0.0 6.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EAQ92098.1 - 9.1e-09 34.7 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 GRAM domain PH_8 PF15409.1 EAQ92098.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EAQ92098.1 - 0.00012 22.2 0.3 0.00054 20.1 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EAQ92098.1 - 0.00019 21.2 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EAQ92098.1 - 0.0059 16.6 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EAQ92098.1 - 0.084 13.0 0.0 0.3 11.2 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain GRAM PF02893.15 EAQ92099.1 - 2.3e-16 59.0 0.0 3.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Glyco_transf_28 PF03033.15 EAQ92099.1 - 1.7e-15 57.0 0.0 3.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EAQ92099.1 - 0.0014 17.2 0.0 0.0024 16.4 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase K_channel_TID PF07941.6 EAQ92099.1 - 0.011 15.9 0.2 0.088 13.0 0.3 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NIF PF03031.13 EAQ92100.1 - 2.6e-27 95.4 0.5 6.3e-27 94.1 0.1 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.17 EAQ92100.1 - 0.0039 16.7 0.0 0.95 9.1 0.0 3.3 2 1 1 3 3 3 1 Biotin-requiring enzyme Cnd1_N PF12922.2 EAQ92101.1 - 4.9e-57 192.2 3.5 5.9e-57 192.0 0.1 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EAQ92101.1 - 2.2e-54 184.0 3.0 5.3e-52 176.2 0.2 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAQ92101.1 - 1.9e-11 44.0 1.5 9.6e-05 22.5 0.0 5.7 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EAQ92101.1 - 1e-08 34.5 10.7 0.042 13.9 0.0 7.2 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 EAQ92101.1 - 1.4e-06 28.5 3.1 0.019 15.4 0.1 5.6 5 0 0 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.15 EAQ92101.1 - 0.00071 18.0 2.1 0.018 13.3 0.1 3.1 3 1 0 3 3 3 1 Adaptin N terminal region Cnd3 PF12719.2 EAQ92101.1 - 0.0009 18.3 3.7 0.0067 15.4 0.1 3.4 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 EAQ92101.1 - 0.0041 16.9 0.0 0.94 9.4 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EAQ92101.1 - 0.031 14.2 0.1 5.9 6.9 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.20 EAQ92102.1 - 5.8e-41 140.3 0.0 7.3e-37 126.9 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92102.1 - 2.2e-14 53.1 0.0 2e-08 33.6 0.0 3.5 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 EAQ92102.1 - 0.00011 22.0 0.3 0.021 14.5 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EAQ92102.1 - 0.001 18.1 0.0 0.21 10.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Helicase_C_2 PF13307.1 EAQ92103.1 - 2.3e-56 190.3 0.0 5e-56 189.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EAQ92103.1 - 2.6e-40 137.6 0.0 4.1e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EAQ92103.1 - 0.034 13.9 0.0 9.1 6.0 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAQ92103.1 - 0.15 10.8 0.0 0.88 8.2 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain CAF-1_p150 PF11600.3 EAQ92104.1 - 0.0092 15.3 0.5 0.013 14.9 0.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2803 PF10972.3 EAQ92104.1 - 0.17 11.3 3.9 0.23 10.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) APG6 PF04111.7 EAQ92104.1 - 0.28 10.1 2.8 0.38 9.7 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EAQ92104.1 - 6.3 6.8 12.7 12 5.9 3.9 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 YjgP_YjgQ PF03739.9 EAQ92106.1 - 4.7 5.8 9.6 0.19 10.4 1.6 1.9 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Esterase PF00756.15 EAQ92113.1 - 2.2e-06 27.2 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EAQ92113.1 - 0.00082 18.6 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAQ92113.1 - 0.0019 18.1 0.3 0.003 17.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1664 PF07889.7 EAQ92113.1 - 0.082 12.7 5.0 0.067 12.9 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.10 EAQ92113.1 - 0.13 11.4 3.3 0.19 10.8 2.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.3 EAQ92113.1 - 0.67 9.9 7.5 0.36 10.8 2.7 1.9 2 0 0 2 2 2 0 YlqD protein Sugarporin_N PF11471.3 EAQ92113.1 - 10 5.8 9.1 3 7.5 0.9 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Chitin_synth_2 PF03142.10 EAQ92114.1 - 0.0019 16.6 2.8 0.0019 16.6 1.9 2.1 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EAQ92114.1 - 0.011 15.4 14.5 0.12 12.1 10.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DUF1049 PF06305.6 EAQ92114.1 - 0.028 13.8 0.1 0.074 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4386 PF14329.1 EAQ92115.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Syndecan PF01034.15 EAQ92115.1 - 0.015 14.9 0.2 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_glycop PF01528.11 EAQ92116.1 - 1 7.9 7.5 0.082 11.5 1.3 1.8 2 0 0 2 2 2 0 Herpesvirus glycoprotein M COesterase PF00135.23 EAQ92117.1 - 5.4e-83 279.5 0.0 5.4e-80 269.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAQ92117.1 - 2e-06 27.5 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ92117.1 - 0.024 14.3 0.1 0.052 13.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.17 EAQ92118.1 - 1.1e-40 139.5 0.0 3.6e-36 124.6 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Ank_2 PF12796.2 EAQ92121.1 - 3.9e-11 43.1 0.0 2.7e-05 24.4 0.0 1.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ92121.1 - 2.1e-05 24.9 0.0 4.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EAQ92121.1 - 0.0024 17.5 0.0 1.9 8.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EAQ92121.1 - 0.01 15.9 0.0 0.82 10.1 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_23 PF13489.1 EAQ92122.1 - 1.4e-06 28.1 0.1 0.04 13.6 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain MULE PF10551.4 EAQ92123.1 - 1.3e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ92123.1 - 0.0074 16.7 0.2 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 EAQ92123.1 - 0.1 12.0 2.7 0.24 10.9 1.9 1.6 1 0 0 1 1 1 0 SWIM zinc finger Mito_carr PF00153.22 EAQ92124.1 - 3.1e-13 49.2 6.7 1.5e-09 37.4 0.1 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein NPP1 PF05630.6 EAQ92126.1 - 3.1e-81 272.0 1.1 3.6e-81 271.8 0.8 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF946 PF06101.6 EAQ92126.1 - 0.0014 16.7 0.7 0.002 16.2 0.5 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Glyco_hydro_61 PF03443.9 EAQ92127.1 - 2.6e-36 125.4 0.5 1.6e-22 80.4 0.2 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 AAA_16 PF13191.1 EAQ92128.1 - 6.6e-09 36.0 0.0 1.7e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAQ92128.1 - 7.6e-05 22.8 0.0 0.00064 19.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EAQ92128.1 - 0.00067 19.3 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EAQ92128.1 - 0.032 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EAQ92128.1 - 0.046 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EAQ92128.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Tissue_fac PF01108.12 EAQ92128.1 - 0.26 11.0 1.3 0.61 9.8 0.9 1.6 1 0 0 1 1 1 0 Tissue factor DUF2075 PF09848.4 EAQ92128.1 - 0.41 9.5 0.0 0.67 8.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 EAQ92128.1 - 0.68 8.5 0.0 1.1 7.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF3472 PF11958.3 EAQ92128.1 - 1.4 9.2 2.0 2.6 8.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) Glyco_transf_90 PF05686.7 EAQ92129.1 - 3.9e-16 58.7 0.3 5.1e-10 38.5 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 90 Arginase PF00491.16 EAQ92130.1 - 1.9e-41 142.2 0.2 2.1e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 EAQ92131.1 - 5.9e-07 29.4 11.9 8.9e-07 28.8 8.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain Nebulin PF00880.13 EAQ92132.1 - 0.0092 15.5 0.7 0.17 11.5 0.2 2.3 2 0 0 2 2 2 1 Nebulin repeat Metal_resist PF13801.1 EAQ92132.1 - 0.15 12.0 4.0 0.087 12.8 0.7 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Microtub_assoc PF07989.6 EAQ92134.1 - 1.2e-19 69.9 7.8 1.2e-19 69.9 5.4 7.6 6 1 1 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 EAQ92134.1 - 3.1e-09 36.7 9.5 3.1e-09 36.7 6.6 13.2 13 3 1 15 15 15 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.6 EAQ92134.1 - 0.0037 16.4 2.2 0.0037 16.4 1.5 7.3 3 1 4 7 7 7 1 Sensor protein DegS IncA PF04156.9 EAQ92134.1 - 0.0057 16.2 20.1 0.0057 16.2 13.9 7.6 3 2 4 7 7 7 3 IncA protein Serglycin PF04360.7 EAQ92134.1 - 0.14 11.8 3.5 1 9.0 0.3 3.1 3 1 0 3 3 3 0 Serglycin Reo_sigmaC PF04582.7 EAQ92134.1 - 5.7 6.0 23.4 0.16 11.1 0.9 4.5 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Sec7 PF01369.15 EAQ92136.1 - 5.3e-41 140.3 0.0 9.8e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EAQ92136.1 - 1.9e-18 66.7 0.0 4.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1777 PF08648.7 EAQ92136.1 - 0.00022 21.0 28.9 0.00022 21.0 20.0 3.7 5 0 0 5 5 5 1 Protein of unknown function (DUF1777) adh_short PF00106.20 EAQ92137.1 - 7.1e-23 81.3 6.2 1.9e-16 60.4 3.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAQ92137.1 - 2e-08 34.0 1.9 7.3e-08 32.2 1.2 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EAQ92137.1 - 4.8e-08 33.0 0.2 9.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAQ92137.1 - 0.00065 19.2 0.2 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF605 PF04652.11 EAQ92137.1 - 3.7 6.8 20.7 5.5 6.2 14.4 1.2 1 0 0 1 1 1 0 Vta1 like NAD_binding_10 PF13460.1 EAQ92137.1 - 6.6 6.6 7.1 2 8.3 2.4 2.1 3 1 0 3 3 3 0 NADH(P)-binding UvrC_HhH_N PF08459.6 EAQ92138.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DAGK_cat PF00781.19 EAQ92139.1 - 0.016 14.6 0.0 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Sel1 PF08238.7 EAQ92140.1 - 5.6e-21 74.4 27.6 3e-08 34.0 0.1 7.3 7 0 0 7 7 7 6 Sel1 repeat TPR_8 PF13181.1 EAQ92140.1 - 0.023 14.4 1.0 2 8.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ92140.1 - 0.11 12.1 0.0 0.11 12.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ92140.1 - 0.18 11.4 4.4 0.35 10.5 0.1 3.0 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 EAQ92140.1 - 0.31 11.7 4.3 7.9 7.2 0.0 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ92140.1 - 0.48 10.9 2.9 11 6.6 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 EAQ92141.1 - 2.7e-22 79.3 0.0 3.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EAQ92141.1 - 4.9e-14 52.2 0.0 7.8e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Coatomer_WDAD PF04053.9 EAQ92142.1 - 3.7e-149 497.2 0.0 5.1e-149 496.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EAQ92142.1 - 1.7e-78 264.0 0.1 6.8e-78 262.0 0.1 1.8 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EAQ92142.1 - 1.3e-50 167.5 11.4 1.6e-09 37.2 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EAQ92142.1 - 0.062 11.4 8.7 2.6 6.0 2.0 3.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.15 EAQ92142.1 - 0.071 12.7 0.6 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS UDP-g_GGTase PF06427.6 EAQ92143.1 - 2.2e-45 154.5 0.1 1.3e-22 80.1 0.0 3.3 2 1 1 3 3 3 3 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EAQ92143.1 - 0.00021 20.7 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 SNF2_N PF00176.18 EAQ92144.1 - 1.2e-25 89.9 0.0 1.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ92144.1 - 9.3e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EAQ92144.1 - 0.0033 16.2 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Rad54_N PF08658.5 EAQ92145.1 - 3.2e-65 219.6 3.0 3.7e-65 219.3 2.1 1.1 1 0 0 1 1 1 1 Rad54 N terminal Mito_carr PF00153.22 EAQ92146.1 - 2.4e-45 152.1 0.0 1.3e-18 66.4 0.1 3.8 3 1 1 4 4 4 3 Mitochondrial carrier protein NYN PF01936.13 EAQ92147.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 NYN domain GST_N PF02798.15 EAQ92148.1 - 8.6e-15 54.6 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAQ92148.1 - 2.6e-14 53.2 0.0 5.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAQ92148.1 - 2.4e-12 46.6 0.1 3.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAQ92148.1 - 2.4e-11 43.4 0.0 5.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAQ92148.1 - 1.3e-09 37.7 0.1 2.8e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ92148.1 - 4.9e-06 26.9 0.2 8.1e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bromodomain PF00439.20 EAQ92149.1 - 1.1e-44 150.1 0.6 2.5e-21 75.3 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EAQ92149.1 - 1.5e-15 57.0 0.3 3.6e-15 55.7 0.2 1.7 1 0 0 1 1 1 1 BAH domain Nsp1_C PF05064.8 EAQ92149.1 - 0.0035 16.9 0.7 0.008 15.8 0.5 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF2422 PF10337.4 EAQ92149.1 - 0.069 11.9 1.8 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) AT_hook PF02178.14 EAQ92149.1 - 9.5 6.2 14.7 0.19 11.5 0.8 3.1 2 0 0 2 2 2 0 AT hook motif OTU PF02338.14 EAQ92151.1 - 3.2e-09 37.4 0.0 6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EAQ92151.1 - 0.0028 17.9 0.0 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 PB1 PF00564.19 EAQ92151.1 - 0.032 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 PB1 domain UBX PF00789.15 EAQ92151.1 - 0.041 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 UBX domain FmdA_AmdA PF03069.10 EAQ92152.1 - 4.4e-152 506.0 0.0 5.1e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 EAQ92153.1 - 3.6e-08 33.1 14.7 2e-06 27.3 10.2 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Peptidase_M50 PF02163.17 EAQ92153.1 - 0.058 12.3 0.0 0.1 11.5 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 SKG6 PF08693.5 EAQ92153.1 - 1.3 8.3 4.2 5.4 6.4 2.9 2.1 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Inp1 PF12634.2 EAQ92154.1 - 6.1e-31 107.0 0.0 1.7e-30 105.6 0.0 1.7 1 1 0 1 1 1 1 Inheritance of peroxisomes protein 1 CBS PF00571.23 EAQ92155.1 - 1e-16 60.3 4.1 0.00038 20.1 0.2 5.3 5 0 0 5 5 5 4 CBS domain HEAT_2 PF13646.1 EAQ92156.1 - 6e-23 80.9 15.8 3.3e-09 36.8 0.1 8.1 3 3 5 8 8 8 8 HEAT repeats HEAT PF02985.17 EAQ92156.1 - 1.4e-20 71.4 14.8 0.0025 17.7 0.0 10.2 12 0 0 12 12 10 6 HEAT repeat HEAT_EZ PF13513.1 EAQ92156.1 - 2.6e-15 56.3 22.4 1.3e-07 31.8 0.0 9.8 7 3 5 12 12 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAQ92156.1 - 8e-14 51.8 0.7 0.015 15.6 0.0 7.4 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EAQ92156.1 - 4.9e-09 35.4 0.1 4.9e-05 22.2 0.0 4.6 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EAQ92156.1 - 1.2e-07 31.5 0.0 0.035 13.8 0.0 4.7 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EAQ92156.1 - 2.1e-07 30.5 4.6 0.0092 15.3 0.0 6.2 5 2 2 7 7 7 1 CLASP N terminal Proteasom_PSMB PF10508.4 EAQ92156.1 - 3.8e-05 22.1 0.0 0.00027 19.3 0.0 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF4042 PF13251.1 EAQ92156.1 - 4.6e-05 22.9 0.1 7 6.0 0.0 4.9 5 0 0 5 5 5 2 Domain of unknown function (DUF4042) Xpo1 PF08389.7 EAQ92156.1 - 0.00039 20.3 2.5 0.0025 17.7 0.0 3.5 3 1 1 4 4 3 1 Exportin 1-like protein TAN PF11640.3 EAQ92156.1 - 0.0013 18.4 0.2 0.24 11.1 0.0 3.6 3 1 1 4 4 4 1 Telomere-length maintenance and DNA damage repair Arm PF00514.18 EAQ92156.1 - 0.0029 17.3 14.4 0.82 9.5 0.0 5.9 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat CAS_CSE1 PF03378.10 EAQ92156.1 - 0.014 13.7 0.8 1.2 7.2 0.0 3.5 5 0 0 5 5 5 0 CAS/CSE protein, C-terminus TFCD_C PF12612.3 EAQ92156.1 - 0.026 13.9 2.2 0.57 9.5 0.0 3.7 3 2 0 3 3 3 0 Tubulin folding cofactor D C terminal Dopey_N PF04118.9 EAQ92156.1 - 0.068 11.9 1.2 0.31 9.7 0.0 2.6 3 1 0 3 3 3 0 Dopey, N-terminal DUF3385 PF11865.3 EAQ92156.1 - 0.079 12.8 1.3 69 3.3 0.1 4.9 2 1 1 4 4 4 0 Domain of unknown function (DUF3385) V-ATPase_H_N PF03224.9 EAQ92156.1 - 0.29 10.2 7.2 5.5 6.0 0.1 3.8 2 2 0 2 2 2 0 V-ATPase subunit H PAS_9 PF13426.1 EAQ92157.1 - 2.8e-29 101.5 0.0 1.4e-17 63.9 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EAQ92157.1 - 3.6e-19 68.6 0.0 9.2e-12 44.9 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 EAQ92157.1 - 1.5e-15 56.9 0.0 9.2e-06 25.4 0.0 3.9 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.1 EAQ92157.1 - 3.2e-08 33.4 0.0 9.7e-05 22.2 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EAQ92157.1 - 1.5e-07 31.4 0.0 0.055 13.5 0.0 3.4 3 0 0 3 3 3 2 PAS fold RTA1 PF04479.8 EAQ92160.1 - 6.7e-07 29.0 4.3 1.1e-06 28.3 3.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.1 EAQ92160.1 - 6.2 6.1 8.4 2.2 7.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Rsa3 PF14615.1 EAQ92161.1 - 1.3e-22 78.7 0.5 1.7e-22 78.4 0.3 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 W2 PF02020.13 EAQ92162.1 - 1.8e-16 59.8 4.1 3.4e-16 58.9 2.8 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 EAQ92162.1 - 3.3e-06 26.5 0.0 5.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase HSF_DNA-bind PF00447.12 EAQ92163.1 - 7.6e-33 112.7 0.1 1.4e-32 111.9 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EAQ92163.1 - 3.6e-21 75.2 0.2 3.6e-21 75.2 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain CENP-H PF05837.7 EAQ92163.1 - 0.02 15.0 6.5 0.045 13.9 4.5 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Lgl_C PF08596.5 EAQ92163.1 - 0.081 11.3 0.3 0.13 10.7 0.2 1.2 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal DUF972 PF06156.8 EAQ92163.1 - 0.14 12.5 2.3 0.37 11.1 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) I-set PF07679.11 EAQ92164.1 - 0.00059 19.6 0.2 12 5.8 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin I-set domain DUF1918 PF08940.6 EAQ92164.1 - 0.0026 17.0 0.2 6.4 6.1 0.0 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 EAQ92165.1 - 6.6e-37 126.7 0.2 1.2e-25 89.9 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF810 PF05664.6 EAQ92165.1 - 0.055 11.7 0.1 0.084 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF810) DUF2735 PF10931.3 EAQ92165.1 - 0.18 12.0 2.1 1.5 9.0 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2735) CDP-OH_P_transf PF01066.16 EAQ92166.1 - 1.3e-13 51.0 2.4 2.7e-13 50.0 1.6 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_2b PF00587.20 EAQ92167.1 - 1.1e-35 122.8 0.1 1.2e-34 119.3 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAQ92167.1 - 3.5e-20 71.7 0.1 7.4e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EAQ92167.1 - 1.7e-09 37.3 0.0 3.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain Transglut_core2 PF13369.1 EAQ92168.1 - 1.6e-16 60.1 0.0 2.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box PF00646.28 EAQ92168.1 - 1.2e-08 34.4 1.2 2.9e-08 33.1 0.9 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAQ92168.1 - 7.2e-07 28.8 2.4 1.5e-06 27.8 1.7 1.6 1 0 0 1 1 1 1 F-box-like YccV-like PF08755.6 EAQ92168.1 - 4.4e-06 26.5 0.0 1.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Ytp1 PF10355.4 EAQ92169.1 - 7.3e-114 379.5 7.6 1.1e-113 378.9 5.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EAQ92169.1 - 6.4e-35 118.9 1.9 6.4e-35 118.9 1.3 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) ACT_7 PF13840.1 EAQ92169.1 - 0.13 11.7 0.2 0.36 10.3 0.1 1.8 2 0 0 2 2 2 0 ACT domain Lactamase_B PF00753.22 EAQ92171.1 - 1e-25 90.5 4.5 1.7e-25 89.8 3.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAQ92171.1 - 9.7e-05 21.9 0.1 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UCH PF00443.24 EAQ92172.1 - 2.6e-48 164.4 4.1 4.8e-48 163.5 2.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ92172.1 - 2.1e-32 112.7 1.3 3.6e-32 111.9 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAQ92172.1 - 0.0032 17.5 0.2 0.0032 17.5 0.1 3.0 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein N6-adenineMlase PF10237.4 EAQ92173.1 - 7.4e-56 188.2 0.0 9.6e-56 187.9 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase NAD_binding_10 PF13460.1 EAQ92174.1 - 7.5e-17 61.9 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAQ92174.1 - 4.4e-16 58.8 0.0 6.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAQ92174.1 - 1.1e-15 57.7 0.2 2.9e-15 56.3 0.0 1.8 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ92174.1 - 1.4e-10 40.3 0.1 2.7e-10 39.4 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EAQ92174.1 - 6.3e-09 35.1 0.0 3.1e-07 29.5 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EAQ92174.1 - 0.00016 20.6 0.4 0.0024 16.8 0.3 2.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EAQ92174.1 - 0.00025 20.9 0.1 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ92174.1 - 0.0013 18.4 0.0 0.25 10.9 0.0 2.6 3 0 0 3 3 3 1 KR domain Saccharop_dh PF03435.13 EAQ92174.1 - 0.0077 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EAQ92174.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EAQ92174.1 - 0.036 13.9 0.0 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DDE_Tnp_1_3 PF13612.1 EAQ92174.1 - 0.1 12.3 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain PCI PF01399.22 EAQ92175.1 - 9.5e-11 41.9 0.0 2.6e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain Gaa1 PF04114.9 EAQ92176.1 - 2.6e-92 310.1 0.1 3.3e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.17 EAQ92177.1 - 3.2e-05 23.9 0.7 7.2e-05 22.8 0.2 1.7 1 1 0 1 1 1 1 Rhomboid family Aconitase PF00330.15 EAQ92178.1 - 1.5e-172 574.2 0.0 3.8e-172 572.9 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAQ92178.1 - 6.5e-45 152.4 0.0 1.1e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EAQ92179.1 - 1.1e-09 38.1 0.2 1.8e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EAQ92179.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 U1 zinc finger DUF2410 PF10307.4 EAQ92180.1 - 6.1e-82 273.7 0.0 8.2e-82 273.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Metallopep PF12044.3 EAQ92181.1 - 1.3e-167 557.5 0.0 1.6e-167 557.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EAQ92181.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Jacalin-like lectin domain Reprolysin_2 PF13574.1 EAQ92181.1 - 0.13 12.2 0.5 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EAQ92181.1 - 0.26 10.1 0.8 0.52 9.1 0.5 1.4 1 0 0 1 1 1 0 Peptidase M66 Whi5 PF08528.6 EAQ92183.1 - 2.5e-09 36.5 0.3 5.2e-09 35.4 0.2 1.6 1 0 0 1 1 1 1 Whi5 like SKG6 PF08693.5 EAQ92184.1 - 0.0035 16.6 1.5 0.0035 16.6 1.0 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EAQ92184.1 - 0.25 11.0 0.1 0.49 10.0 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Peptidase_C14 PF00656.17 EAQ92186.1 - 1.8e-74 250.5 0.0 2.3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EAQ92186.1 - 0.067 13.0 0.3 0.57 10.0 0.0 2.4 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain Microtub_assoc PF07989.6 EAQ92187.1 - 1.6e-28 98.2 4.7 1.6e-28 98.2 3.3 12.0 11 3 1 13 13 13 1 Microtubule associated PACT_coil_coil PF10495.4 EAQ92187.1 - 8.5e-13 48.0 0.0 6.5e-12 45.2 0.0 2.6 1 1 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cast PF10174.4 EAQ92187.1 - 7.8e-06 24.2 102.3 7.8e-06 24.2 70.9 4.2 1 1 2 3 3 2 1 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 EAQ92187.1 - 4.2e-05 22.8 53.6 0.0028 16.8 1.3 7.6 2 2 6 9 9 9 6 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 EAQ92187.1 - 0.00036 20.5 8.4 0.00036 20.5 5.8 14.3 4 2 12 16 16 14 1 Seryl-tRNA synthetase N-terminal domain WEMBL PF05701.6 EAQ92187.1 - 0.00059 18.4 193.4 0.017 13.6 37.0 6.9 2 1 2 5 5 5 4 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EAQ92187.1 - 0.00081 17.2 75.1 0.00081 17.2 52.0 6.3 1 1 2 5 5 5 2 Myosin tail AAA_13 PF13166.1 EAQ92187.1 - 0.0017 16.9 131.1 0.034 12.6 13.8 5.8 1 1 5 6 6 6 5 AAA domain IncA PF04156.9 EAQ92187.1 - 0.0021 17.6 25.8 0.0021 17.6 17.9 11.0 2 2 8 10 10 9 5 IncA protein TPR_MLP1_2 PF07926.7 EAQ92187.1 - 0.0024 17.6 17.9 0.0024 17.6 12.4 12.7 3 1 9 12 12 12 4 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 EAQ92187.1 - 0.0026 17.4 8.8 0.0026 17.4 6.1 11.9 2 2 8 11 11 10 3 Mnd1 family ALIX_LYPXL_bnd PF13949.1 EAQ92187.1 - 0.0036 16.3 23.2 0.0036 16.3 16.1 8.3 1 1 5 7 7 2 1 ALIX V-shaped domain binding to HIV HALZ PF02183.13 EAQ92187.1 - 0.0042 16.7 1.1 0.0042 16.7 0.8 13.7 14 1 1 15 15 15 1 Homeobox associated leucine zipper Filament PF00038.16 EAQ92187.1 - 0.55 9.6 185.7 0.011 15.2 28.3 10.6 2 1 4 8 8 8 0 Intermediate filament protein DUF3993 PF13158.1 EAQ92187.1 - 1.8 8.3 4.3 4.8 6.9 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Spc7 PF08317.6 EAQ92187.1 - 6.6 5.2 160.1 0.063 11.9 11.8 9.0 1 1 10 11 11 11 0 Spc7 kinetochore protein DUF4611 PF15387.1 EAQ92188.1 - 0.031 14.4 4.3 0.32 11.1 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DivIC PF04977.10 EAQ92188.1 - 0.36 10.3 2.3 21 4.6 0.1 2.9 3 0 0 3 3 3 0 Septum formation initiator Vac14_Fig4_bd PF11916.3 EAQ92189.1 - 2.1e-49 167.1 11.4 1e-25 89.9 1.1 2.8 2 1 1 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EAQ92189.1 - 2.5e-45 152.7 0.2 1.4e-42 143.9 0.0 3.4 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EAQ92189.1 - 3.3e-08 32.9 1.3 0.00025 20.8 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EAQ92189.1 - 1.7e-06 28.3 6.7 0.00013 22.3 0.2 5.3 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EAQ92189.1 - 1.9e-05 24.8 4.2 0.011 16.0 0.0 4.6 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.18 EAQ92189.1 - 0.00092 18.9 0.0 0.12 12.2 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EAQ92189.1 - 0.0018 18.1 2.1 1.8 8.4 0.4 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 FA_desaturase PF00487.19 EAQ92191.1 - 2.9e-20 72.7 1.0 4.6e-20 72.1 0.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EAQ92191.1 - 5.9e-12 45.2 0.0 1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_dim PF02852.17 EAQ92192.1 - 2.1e-39 133.9 0.0 8.1e-39 132.0 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EAQ92192.1 - 4e-37 128.0 17.6 3.9e-36 124.8 11.8 3.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ92192.1 - 5.5e-27 93.9 10.9 1.6e-22 79.7 1.2 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ92192.1 - 4.9e-12 45.6 3.2 2.4e-06 27.4 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ92192.1 - 1.8e-10 40.2 16.2 7.6e-05 21.7 1.4 4.2 3 1 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAQ92192.1 - 7.4e-10 39.2 1.1 8e-06 26.0 0.3 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAQ92192.1 - 9.5e-10 38.1 5.9 1.2e-09 37.7 0.2 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EAQ92192.1 - 1.9e-08 33.5 10.5 6.1e-07 28.6 2.3 3.1 2 2 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAQ92192.1 - 8.6e-08 31.4 8.9 6.8e-07 28.4 1.9 3.4 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EAQ92192.1 - 1.9e-07 29.9 12.8 7.4e-05 21.3 1.2 4.0 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_3 PF01494.14 EAQ92192.1 - 1.4e-06 27.6 8.0 0.081 11.9 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain AlaDh_PNT_C PF01262.16 EAQ92192.1 - 8.8e-06 25.3 2.6 0.023 14.2 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EAQ92192.1 - 2.7e-05 23.3 1.8 0.00019 20.6 0.1 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EAQ92192.1 - 4.8e-05 22.4 1.5 0.05 12.5 0.0 2.4 3 0 0 3 3 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EAQ92192.1 - 0.00065 19.9 1.2 0.96 9.7 0.0 2.9 2 0 0 2 2 2 2 Putative NAD(P)-binding 3HCDH_N PF02737.13 EAQ92192.1 - 0.018 14.7 0.6 0.018 14.7 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EAQ92192.1 - 0.026 13.4 3.6 0.04 12.8 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EAQ92192.1 - 0.027 13.1 5.0 0.05 12.2 0.5 2.4 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EAQ92192.1 - 0.059 12.7 3.6 0.53 9.6 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3343 PF11823.3 EAQ92192.1 - 0.063 12.5 0.1 9.2 5.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) 2-Hacid_dh_C PF02826.14 EAQ92192.1 - 0.15 11.2 0.8 6.4 5.8 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.14 EAQ92192.1 - 0.19 9.8 2.1 0.8 7.8 0.3 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Amino_oxidase PF01593.19 EAQ92192.1 - 0.41 9.6 2.5 0.81 8.6 0.1 2.3 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase MIF4G PF02854.14 EAQ92193.1 - 2.8e-22 79.1 0.2 3.3e-19 69.1 0.0 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EAQ92193.1 - 4.2e-15 55.4 0.1 5.4e-14 51.8 0.0 3.0 4 1 0 4 4 4 1 MA3 domain SRP14 PF02290.10 EAQ92194.1 - 1.8e-22 79.0 0.0 5.5e-22 77.5 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle 14kD protein RRM_1 PF00076.17 EAQ92195.1 - 5.7e-54 179.6 0.0 3.4e-18 65.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ92195.1 - 1.8e-43 146.3 0.0 1.1e-14 54.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ92195.1 - 2e-24 85.2 0.0 1.6e-06 27.8 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAQ92195.1 - 7.7e-07 28.7 0.0 0.24 11.2 0.0 4.0 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 EAQ92195.1 - 2.3e-06 27.4 0.0 0.36 10.7 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 EAQ92195.1 - 0.0017 17.7 0.0 0.077 12.3 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain DUF1777 PF08648.7 EAQ92195.1 - 0.12 12.1 13.4 0.21 11.3 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) THRAP3_BCLAF1 PF15440.1 EAQ92195.1 - 1.9 7.0 17.9 2.6 6.5 12.4 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Hepatitis_core PF00906.15 EAQ92195.1 - 9.9 5.7 13.7 16 5.0 9.5 1.3 1 0 0 1 1 1 0 Hepatitis core antigen COQ9 PF08511.6 EAQ92196.1 - 5.6e-26 89.8 0.0 9.3e-26 89.1 0.0 1.4 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.14 EAQ92197.1 - 9.8e-27 93.6 0.0 2e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAQ92197.1 - 7.1e-14 52.6 12.7 7.1e-14 52.6 8.8 4.4 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EAQ92197.1 - 2.5e-06 27.6 2.8 0.00081 19.4 1.5 2.9 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EAQ92197.1 - 0.0002 21.1 0.0 0.00067 19.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EAQ92197.1 - 0.00027 20.1 0.0 0.00027 20.1 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EAQ92197.1 - 0.00085 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EAQ92197.1 - 0.089 11.9 0.7 7.2 5.6 0.1 2.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EAQ92197.1 - 0.15 12.3 19.2 12 6.1 5.6 4.9 2 2 0 2 2 2 0 ABC transporter SGT1 PF07093.6 EAQ92198.1 - 1.5e-122 409.9 0.0 9.3e-121 404.0 0.0 2.0 1 1 0 1 1 1 1 SGT1 protein DUF3439 PF11921.3 EAQ92198.1 - 0.11 12.2 1.3 0.19 11.5 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) THUMP PF02926.12 EAQ92201.1 - 2.8e-09 36.9 0.1 1.8e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 THUMP domain TPP_enzyme_N PF02776.13 EAQ92202.1 - 3.4e-34 117.7 0.0 1.2e-33 116.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAQ92202.1 - 2.3e-30 105.1 0.0 4.7e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EAQ92202.1 - 1.2e-15 57.3 0.7 5e-15 55.3 0.0 2.3 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EAQ92202.1 - 0.05 12.5 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EAQ92202.1 - 0.074 11.7 0.1 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component HEM4 PF02602.10 EAQ92203.1 - 1.2e-38 132.6 0.0 1.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CBM_X PF06204.6 EAQ92203.1 - 0.096 12.1 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative carbohydrate binding domain TLD PF07534.11 EAQ92204.1 - 1.8e-25 89.5 0.0 1.3e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.20 EAQ92205.1 - 1.2e-74 250.7 0.0 1.5e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92205.1 - 7.4e-32 110.4 0.0 9.6e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ92205.1 - 0.00031 19.8 0.0 0.00073 18.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAQ92205.1 - 0.0021 17.1 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ92205.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAQ92205.1 - 0.04 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 EAQ92205.1 - 0.087 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 Sec23_trunk PF04811.10 EAQ92206.1 - 5.5e-71 238.7 0.0 1.2e-70 237.6 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EAQ92206.1 - 2.7e-24 84.5 0.0 5.9e-23 80.2 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EAQ92206.1 - 4.3e-18 65.5 0.1 8.7e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAQ92206.1 - 7e-18 63.9 5.3 1.3e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EAQ92206.1 - 1.4e-10 40.7 0.0 3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF1705 PF08019.7 EAQ92207.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) CD34_antigen PF06365.7 EAQ92207.1 - 0.099 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PsbN PF02468.10 EAQ92207.1 - 0.12 12.0 0.2 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Fungal_trans_2 PF11951.3 EAQ92208.1 - 1.2e-07 30.7 0.0 2.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAF-1_p150 PF11600.3 EAQ92208.1 - 4.4 6.6 4.9 7 5.9 3.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Xpo1 PF08389.7 EAQ92209.1 - 9.5e-08 32.0 0.0 2.1e-05 24.4 0.0 2.9 2 0 0 2 2 2 2 Exportin 1-like protein IBN_N PF03810.14 EAQ92209.1 - 0.00096 19.0 1.7 0.013 15.3 0.0 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain WD40 PF00400.27 EAQ92210.1 - 0.0022 17.7 0.1 5.8 6.9 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF1917 PF08939.5 EAQ92211.1 - 4.4e-79 265.6 0.0 5.3e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) IF4E PF01652.13 EAQ92211.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Acetyltransf_1 PF00583.19 EAQ92212.1 - 3.9e-16 58.8 0.0 5.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ92212.1 - 3.1e-08 33.6 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAQ92212.1 - 4.6e-08 32.6 0.0 6.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EAQ92212.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAQ92212.1 - 1.7e-07 31.4 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAQ92212.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAQ92212.1 - 1.3e-05 25.0 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAQ92212.1 - 0.0002 21.3 0.0 0.00037 20.4 0.0 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAQ92212.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LCAT PF02450.10 EAQ92213.1 - 7.9e-76 255.5 0.2 2.5e-46 158.3 0.0 2.4 2 1 1 3 3 3 2 Lecithin:cholesterol acyltransferase DUF2013 PF09431.5 EAQ92214.1 - 1.2e-50 170.8 1.1 1.2e-50 170.8 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Pathogen_betaC1 PF09593.5 EAQ92214.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-satellite pathogenicity beta C1 protein Ribosomal_S17 PF00366.15 EAQ92215.1 - 5.5e-08 32.7 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 AAA PF00004.24 EAQ92216.1 - 3.5e-38 130.7 0.0 7.3e-38 129.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EAQ92216.1 - 2e-08 34.0 0.1 1.2e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EAQ92216.1 - 2.2e-05 24.5 1.0 0.0002 21.4 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAQ92216.1 - 4.1e-05 22.7 0.0 9e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EAQ92216.1 - 0.00048 18.9 0.1 0.00087 18.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EAQ92216.1 - 0.00056 19.9 1.7 0.0084 16.1 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EAQ92216.1 - 0.0015 17.9 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EAQ92216.1 - 0.0019 17.9 0.0 0.0068 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAQ92216.1 - 0.002 17.8 1.2 0.028 14.1 0.0 2.9 3 0 0 3 3 2 1 Part of AAA domain Mg_chelatase PF01078.16 EAQ92216.1 - 0.0036 16.4 0.6 0.0082 15.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EAQ92216.1 - 0.0039 16.1 0.0 0.0083 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EAQ92216.1 - 0.004 17.0 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 EAQ92216.1 - 0.0045 16.5 0.1 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAQ92216.1 - 0.0046 16.8 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAQ92216.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ92216.1 - 0.012 16.4 0.0 0.099 13.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAQ92216.1 - 0.021 14.2 0.4 0.21 10.9 0.1 2.6 1 1 2 3 3 3 0 AAA domain AAA_24 PF13479.1 EAQ92216.1 - 0.021 14.3 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ92216.1 - 0.027 14.4 0.6 0.25 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EAQ92216.1 - 0.064 12.9 0.0 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 EAQ92216.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 EAQ92216.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EAQ92216.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EAQ92216.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase COG6 PF06419.6 EAQ92217.1 - 3.7e-233 775.1 10.1 4.3e-233 774.9 7.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DASH_Dad3 PF08656.5 EAQ92217.1 - 0.016 14.9 0.1 0.18 11.5 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 Seryl_tRNA_N PF02403.17 EAQ92217.1 - 1.1 9.3 8.2 0.12 12.3 1.1 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG9 PF04109.11 EAQ92218.1 - 9.3e-99 330.8 9.2 6.4e-52 176.6 3.2 2.1 1 1 1 2 2 2 2 Autophagy protein Apg9 Mito_carr PF00153.22 EAQ92219.1 - 1.6e-72 239.2 6.5 9.5e-26 89.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 EAQ92220.1 - 6.4e-24 83.4 1.9 6.4e-24 83.4 1.3 2.6 4 0 0 4 4 4 1 DnaJ domain TPR_11 PF13414.1 EAQ92220.1 - 2.6e-12 46.1 9.9 0.00024 20.6 0.0 4.9 2 2 3 5 5 5 5 TPR repeat TPR_14 PF13428.1 EAQ92220.1 - 1.1e-11 44.2 4.1 0.31 11.7 0.0 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ92220.1 - 1.3e-11 44.8 4.8 0.0027 18.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ92220.1 - 1.8e-09 36.7 11.5 0.14 12.1 0.0 7.3 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ92220.1 - 6.3e-09 35.5 1.9 5.5e-05 22.9 0.3 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ92220.1 - 7.3e-09 34.8 5.3 0.001 18.5 0.0 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ92220.1 - 9.1e-09 34.4 2.2 0.15 11.9 0.0 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.12 EAQ92220.1 - 0.00058 20.1 6.9 0.044 14.0 0.0 3.6 2 2 1 3 3 3 2 Bacterial transcriptional activator domain TPR_12 PF13424.1 EAQ92220.1 - 0.00092 19.1 13.5 0.11 12.4 2.6 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ92220.1 - 0.0011 19.2 6.5 1.6 9.3 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ92220.1 - 0.0016 18.7 5.3 1.3 9.3 0.0 4.6 2 2 3 6 6 6 1 Tetratricopeptide repeat SLS PF14611.1 EAQ92220.1 - 0.011 15.1 0.4 0.023 14.1 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator TPR_17 PF13431.1 EAQ92220.1 - 0.015 15.4 0.2 12 6.4 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ92220.1 - 0.11 12.3 6.9 3 7.8 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Gar1 PF04410.9 EAQ92221.1 - 1.2e-44 151.4 0.1 1.2e-44 151.4 0.1 1.8 1 1 0 2 2 2 1 Gar1/Naf1 RNA binding region Prominin PF05478.6 EAQ92222.1 - 0.0003 18.5 0.7 0.00043 17.9 0.5 1.1 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.7 EAQ92222.1 - 0.43 10.3 1.9 0.5 10.1 0.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EMG1 PF03587.9 EAQ92224.1 - 8.3e-78 260.3 0.0 9.7e-78 260.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Cys_Met_Meta_PP PF01053.15 EAQ92226.1 - 1.1e-32 112.8 0.0 1.6e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EAQ92226.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SPX PF03105.14 EAQ92227.1 - 9.2e-30 104.3 1.0 1.2e-29 103.9 0.7 1.0 1 0 0 1 1 1 1 SPX domain DnaJ PF00226.26 EAQ92228.1 - 1.7e-22 78.9 0.2 1.7e-22 78.9 0.1 2.6 2 1 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EAQ92228.1 - 3.6e-11 42.8 2.1 8.8e-11 41.6 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ92228.1 - 5.7e-10 39.0 2.1 1.6e-09 37.5 1.5 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAQ92228.1 - 3.4e-05 23.8 4.1 0.0001 22.3 0.7 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EAQ92228.1 - 0.0071 16.6 4.3 0.066 13.5 0.4 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF2387 PF09526.5 EAQ92228.1 - 0.015 15.2 3.3 0.053 13.4 2.3 1.9 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-C2H2_4 PF13894.1 EAQ92228.1 - 0.041 14.2 3.9 0.13 12.6 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EAQ92228.1 - 0.25 11.2 2.9 0.3 11.0 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_C54 PF03416.14 EAQ92229.1 - 2.6e-76 256.4 0.0 3.1e-46 157.7 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 R3H PF01424.17 EAQ92230.1 - 1.5e-12 46.9 0.0 3.7e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EAQ92230.1 - 4.1e-11 42.4 3.4 9.4e-11 41.3 2.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EAQ92230.1 - 0.061 13.1 3.4 0.19 11.5 1.4 2.4 2 0 0 2 2 2 0 DExH-box splicing factor binding site Histone PF00125.19 EAQ92231.1 - 9.4e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAQ92231.1 - 4e-05 23.5 0.0 9.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EAQ92231.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EAQ92231.1 - 0.024 14.1 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EAQ92231.1 - 0.03 14.8 0.5 0.041 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Glyco_hydro_53 PF07745.8 EAQ92231.1 - 0.064 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Histone PF00125.19 EAQ92232.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Complex1_LYR PF05347.10 EAQ92233.1 - 5.2e-08 32.5 1.5 6.8e-08 32.1 1.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAQ92233.1 - 3.8e-06 27.0 0.8 4.8e-06 26.6 0.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 EAQ92234.1 - 2.2e-78 262.7 0.0 2.9e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EAQ92234.1 - 1.6e-17 62.8 1.1 2.9e-17 62.0 0.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EAQ92234.1 - 0.00035 19.8 0.2 0.0043 16.2 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EAQ92234.1 - 0.0024 17.4 0.2 0.082 12.5 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EAQ92234.1 - 0.0056 17.0 0.2 2 8.8 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein DUF3614 PF12267.3 EAQ92234.1 - 0.037 14.3 0.1 0.21 11.8 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) AA_permease PF00324.16 EAQ92235.1 - 7.9e-24 83.8 12.1 3.5e-23 81.7 8.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ92235.1 - 6e-09 34.9 7.4 7.9e-09 34.5 5.1 1.2 1 0 0 1 1 1 1 Amino acid permease DDE_1 PF03184.14 EAQ92238.1 - 6.3e-37 126.8 0.0 1.1e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ92238.1 - 1.6e-12 46.7 0.2 3e-12 45.8 0.2 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ92238.1 - 2e-10 40.2 0.0 4.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EAQ92239.1 - 2.6e-25 88.8 0.0 7.9e-25 87.2 0.0 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ92239.1 - 8.1e-11 41.3 0.0 1.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EAQ92239.1 - 0.00094 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TH1 PF04858.8 EAQ92239.1 - 0.15 10.1 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 TH1 protein DDE_1 PF03184.14 EAQ92242.1 - 1.2e-11 44.1 0.0 1.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EAQ92243.1 - 1.8e-30 105.7 0.0 3.4e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ92243.1 - 1.4e-11 43.7 0.1 2.5e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ92243.1 - 4e-05 23.3 0.5 9.9e-05 22.0 0.0 2.0 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EAQ92243.1 - 0.0082 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_N PF04218.8 EAQ92243.1 - 0.067 12.6 0.1 0.2 11.0 0.1 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain RNase_H PF00075.19 EAQ92245.1 - 0.0022 18.3 0.1 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Helitron_like_N PF14214.1 EAQ92246.1 - 9.3e-46 155.8 1.6 1.5e-45 155.1 1.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_min_tail PF05939.8 EAQ92246.1 - 0.1 12.5 0.3 6.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Phage minor tail protein DDE_1 PF03184.14 EAQ92247.1 - 1.6e-30 105.8 0.0 2.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EAQ92247.1 - 3.2e-05 23.6 0.5 8.3e-05 22.3 0.0 2.0 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EAQ92247.1 - 0.0065 16.2 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EAQ92248.1 - 3.3e-08 32.9 0.1 2.3e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ92248.1 - 4.5e-07 29.3 0.2 1e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EAQ92248.1 - 0.068 12.8 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain NUMOD1 PF07453.8 EAQ92248.1 - 0.16 11.8 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 NUMOD1 domain DDE_1 PF03184.14 EAQ92249.1 - 3.4e-22 78.6 0.0 4.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EAQ92249.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ92251.1 - 1.7e-07 30.7 0.0 3.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Mnd1 PF03962.10 EAQ92251.1 - 0.086 12.4 2.5 0.12 12.0 1.7 1.3 1 0 0 1 1 1 0 Mnd1 family RVT_1 PF00078.22 EAQ92252.1 - 7.8e-40 136.5 0.0 1.1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF680 PF05079.7 EAQ92254.1 - 0.041 14.3 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF680) Sulfate_transp PF00916.15 EAQ92256.1 - 2.8e-51 174.1 4.5 2.8e-51 174.1 3.1 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAQ92256.1 - 1.3e-30 104.8 1.9 1.3e-30 104.8 1.3 3.2 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif MotB_plug PF13677.1 EAQ92256.1 - 0.099 11.9 0.5 0.23 10.7 0.3 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB GST_C_3 PF14497.1 EAQ92257.1 - 5.8e-11 42.7 0.0 8.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ92257.1 - 5e-08 32.8 0.0 8.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAQ92257.1 - 3.9e-06 26.9 0.0 0.00019 21.5 0.0 2.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAQ92257.1 - 2.9e-05 23.8 0.0 5.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S15 PF00312.17 EAQ92257.1 - 0.13 11.9 0.2 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 zf-C2H2_4 PF13894.1 EAQ92260.1 - 0.029 14.7 2.5 3.2 8.2 0.8 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger Fungal_trans_2 PF11951.3 EAQ92261.1 - 5.7e-13 48.2 0.2 2.3e-12 46.2 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Patatin PF01734.17 EAQ92263.1 - 2e-22 80.1 0.0 1.2e-21 77.5 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4449 PF14613.1 EAQ92264.1 - 6.8e-05 22.8 0.1 0.0003 20.7 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 EAQ92264.1 - 0.013 15.1 0.0 0.12 11.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF1828 YpzI PF14140.1 EAQ92266.1 - 1.1 8.8 11.2 13 5.3 0.1 4.0 4 0 0 4 4 4 0 YpzI-like protein Excalibur PF05901.6 EAQ92266.1 - 1.2 9.5 7.4 30 5.0 0.1 4.1 4 0 0 4 4 4 0 Excalibur calcium-binding domain DUF2580 PF10824.3 EAQ92266.1 - 9.8 6.5 8.5 34 4.8 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2580) WD40 PF00400.27 EAQ92267.1 - 1.5e-24 84.8 15.4 6.3e-09 35.3 0.0 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EAQ92267.1 - 0.00011 20.5 1.0 0.065 11.3 0.1 3.2 2 1 1 4 4 4 2 Nucleoporin Nup120/160 UAF_Rrn10 PF05234.6 EAQ92268.1 - 0.13 12.2 0.0 0.65 10.0 0.0 2.0 1 1 0 1 1 1 0 UAF complex subunit Rrn10 Zn_clus PF00172.13 EAQ92270.1 - 4.2e-07 29.7 13.6 6.4e-07 29.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.7 EAQ92271.1 - 8.6e-43 146.1 0.0 2.6e-42 144.5 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 PBP1_TM PF14812.1 EAQ92273.1 - 1.5 9.1 7.8 4 7.8 0.3 4.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORMDL PF04061.9 EAQ92275.1 - 4.8e-60 201.0 3.0 5.6e-60 200.8 2.1 1.0 1 0 0 1 1 1 1 ORMDL family MIP-T3 PF10243.4 EAQ92277.1 - 0.042 12.3 14.7 0.068 11.6 10.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Lin-8 PF03353.10 EAQ92277.1 - 0.67 9.1 12.8 1.1 8.4 8.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Response_reg PF00072.19 EAQ92278.1 - 5.1e-28 97.3 0.2 8.9e-28 96.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EAQ92278.1 - 5.3e-28 96.9 0.0 1.5e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EAQ92278.1 - 9.3e-14 51.1 0.0 1.9e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EAQ92278.1 - 2.2e-06 27.7 1.1 0.073 13.2 0.0 3.5 3 0 0 3 3 3 2 HAMP domain PP2C_C PF07830.8 EAQ92278.1 - 0.24 11.5 1.9 21 5.3 0.0 3.3 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain CMD PF02627.15 EAQ92279.1 - 1.9e-08 34.0 0.2 9.5e-08 31.7 0.1 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.13 EAQ92279.1 - 0.052 12.8 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 BRCA2 repeat Pkinase PF00069.20 EAQ92281.1 - 9.1e-10 38.1 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAQ92281.1 - 8.5e-09 35.4 0.9 0.00031 20.5 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EAQ92281.1 - 2.6e-07 29.9 0.0 2.2e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAQ92281.1 - 0.00031 20.1 0.0 0.0032 16.8 0.0 2.3 2 1 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 EAQ92281.1 - 0.0044 16.1 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.16 EAQ92282.1 - 1.2e-10 40.6 0.0 1.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SLH PF00395.15 EAQ92282.1 - 0.18 11.5 0.7 27 4.6 0.2 2.6 2 0 0 2 2 2 0 S-layer homology domain Clat_adaptor_s PF01217.15 EAQ92283.1 - 6.8e-41 139.3 0.3 8.8e-41 138.9 0.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 EAQ92284.1 - 1.7e-50 171.3 0.0 2.7e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator PP2C PF00481.16 EAQ92285.1 - 1e-81 274.1 0.7 1.3e-81 273.7 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAQ92285.1 - 0.0035 16.7 0.4 0.0077 15.6 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C He_PIG PF05345.7 EAQ92286.1 - 3.1e-10 39.9 11.6 0.0023 17.9 0.2 4.3 4 0 0 4 4 4 3 Putative Ig domain Methyltransf_16 PF10294.4 EAQ92287.1 - 1.3e-47 161.4 0.0 1.6e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EAQ92287.1 - 0.018 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EAQ92287.1 - 0.049 13.2 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ92287.1 - 0.16 12.5 0.1 0.44 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CAP_N PF01213.14 EAQ92288.1 - 0.04 13.2 2.3 0.16 11.2 1.5 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DPBB_1 PF03330.13 EAQ92288.1 - 0.044 13.8 0.1 0.35 10.8 0.0 2.3 2 1 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Mito_fiss_reg PF05308.6 EAQ92288.1 - 0.071 12.4 4.6 0.091 12.1 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1712 PF08217.6 EAQ92289.1 - 1.5e-13 49.8 0.0 1.2e-09 37.0 0.0 2.9 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) KH_1 PF00013.24 EAQ92290.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 KH domain Exo70 PF03081.10 EAQ92290.1 - 0.21 10.3 0.0 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Pex24p PF06398.6 EAQ92291.1 - 1.3e-05 24.2 3.0 2e-05 23.5 2.1 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Apolipoprotein PF01442.13 EAQ92292.1 - 0.0067 15.9 0.2 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain HrpB7 PF09486.5 EAQ92292.1 - 0.01 15.7 2.1 0.015 15.2 1.5 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Enolase_N PF03952.11 EAQ92292.1 - 0.017 15.0 0.6 0.022 14.6 0.4 1.2 1 0 0 1 1 1 0 Enolase, N-terminal domain BTV_NS2 PF04514.7 EAQ92292.1 - 0.075 11.9 1.3 0.083 11.7 0.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ApoLp-III PF07464.6 EAQ92292.1 - 0.14 12.2 2.8 0.18 11.8 1.9 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FliE PF02049.13 EAQ92292.1 - 0.14 12.1 0.8 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE ETRAMP PF09716.5 EAQ92292.1 - 9.6 6.2 7.0 24 4.9 0.8 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PRP1_N PF06424.7 EAQ92293.1 - 2.8e-48 163.6 6.6 2.8e-48 163.6 4.6 2.5 3 0 0 3 3 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EAQ92293.1 - 1.4e-29 99.8 45.9 0.0002 21.6 0.0 13.9 4 3 10 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ92293.1 - 8.3e-23 80.5 32.1 5.6e-06 26.6 0.5 9.6 9 1 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ92293.1 - 3e-19 69.1 38.0 0.00011 22.8 0.0 9.2 5 1 5 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ92293.1 - 8.3e-09 34.9 19.5 0.023 14.3 0.1 8.6 5 4 4 10 10 10 3 TPR repeat TPR_2 PF07719.12 EAQ92293.1 - 1.5e-08 33.9 19.5 0.34 10.9 0.1 11.1 11 1 1 12 12 12 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EAQ92293.1 - 2.4e-06 26.6 16.2 0.024 13.5 0.0 5.7 3 2 2 5 5 5 4 NRDE-2, necessary for RNA interference TPR_8 PF13181.1 EAQ92293.1 - 3.5e-06 26.3 0.0 0.86 9.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EAQ92293.1 - 4.2e-06 26.0 20.9 0.0019 17.3 1.4 5.0 2 2 0 4 4 4 3 Tetratricopeptide repeat NARP1 PF12569.3 EAQ92293.1 - 3e-05 23.0 10.1 0.29 9.8 0.0 5.8 3 1 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 EAQ92293.1 - 6.6e-05 22.7 19.1 0.033 14.1 0.1 8.5 6 4 1 8 8 8 1 Tetratricopeptide repeat Suf PF05843.9 EAQ92293.1 - 9e-05 22.3 0.1 13 5.3 0.0 4.8 4 1 1 5 5 5 0 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EAQ92293.1 - 0.00011 22.0 8.1 31 5.0 0.0 9.7 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ92293.1 - 0.00016 21.1 0.4 0.21 11.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ92293.1 - 0.092 12.6 22.8 0.19 11.5 0.1 6.8 6 2 0 6 6 6 0 Tetratricopeptide repeat FUSC_2 PF13515.1 EAQ92294.1 - 2.1e-20 72.9 0.7 2.1e-20 72.9 0.5 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EAQ92294.1 - 3e-06 26.1 3.2 0.0035 16.0 0.5 3.7 4 0 0 4 4 4 2 Aluminium activated malate transporter Inhibitor_I53 PF11714.3 EAQ92294.1 - 4.6 7.2 0.0 4.6 7.2 0.0 3.0 4 0 0 4 4 4 0 Thrombin inhibitor Madanin HAD_2 PF13419.1 EAQ92295.1 - 4.3e-10 40.0 0.0 5.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ92295.1 - 3e-07 30.0 0.7 4.7e-07 29.4 0.5 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EAQ92295.1 - 7.4e-05 23.2 0.0 0.00029 21.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EAQ92296.1 - 9.4e-53 179.0 0.0 1.4e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92296.1 - 1.3e-35 122.7 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ92296.1 - 7.1e-06 25.1 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EAQ92296.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EAQ92296.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SH2_2 PF14633.1 EAQ92297.1 - 1.8e-85 285.4 0.1 1.8e-85 285.4 0.1 2.5 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EAQ92297.1 - 5.4e-34 116.7 1.2 5.4e-34 116.7 0.8 5.3 5 2 1 6 6 6 1 Death-like domain of SPT6 HHH_7 PF14635.1 EAQ92297.1 - 8.3e-31 106.1 0.0 2.2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EAQ92297.1 - 8.5e-31 106.5 0.0 6.5e-30 103.6 0.0 2.6 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EAQ92297.1 - 1.2e-24 86.2 35.2 1.2e-24 86.2 24.4 6.3 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EAQ92297.1 - 6.2e-17 61.7 0.8 6.2e-17 61.7 0.6 2.8 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EAQ92297.1 - 0.00027 20.6 0.0 0.00076 19.2 0.0 1.8 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EAQ92297.1 - 0.00059 19.8 2.0 0.00083 19.4 0.2 2.2 2 0 0 2 2 2 1 S1 RNA binding domain HHH_3 PF12836.2 EAQ92297.1 - 0.0025 17.7 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Oxysterol_BP PF01237.13 EAQ92298.1 - 1.5e-107 359.1 0.0 3.4e-107 358.0 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EAQ92298.1 - 5.7e-39 132.0 1.7 2.8e-38 129.8 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EAQ92298.1 - 5e-06 26.6 0.0 2.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EAQ92298.1 - 0.002 18.3 1.3 0.073 13.3 0.9 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain GOLD_2 PF13897.1 EAQ92298.1 - 0.02 15.1 1.0 0.7 10.1 0.0 2.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Hydantoinase_B PF02538.9 EAQ92299.1 - 1.1e-173 578.3 0.1 8.1e-94 314.7 0.0 3.1 1 1 1 3 3 3 3 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EAQ92299.1 - 4.6e-95 318.0 0.5 9e-95 317.0 0.3 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EAQ92299.1 - 6.1e-55 185.4 0.9 2.4e-53 180.2 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pkinase PF00069.20 EAQ92300.1 - 5.1e-45 153.6 0.0 6.9e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92300.1 - 5.5e-19 68.2 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EAQ92300.1 - 3.4e-16 59.1 0.4 5.5e-16 58.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EAQ92300.1 - 1.1e-05 24.5 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 EAQ92300.1 - 0.0084 14.7 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EAQ92300.1 - 0.052 13.2 0.6 0.1 12.2 0.2 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family IlvC PF01450.14 EAQ92300.1 - 0.088 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF92 PF01940.11 EAQ92301.1 - 6e-69 231.6 5.6 8e-69 231.2 3.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Abi PF02517.11 EAQ92301.1 - 0.11 12.6 2.3 8 6.6 0.0 2.7 1 1 1 2 2 2 0 CAAX protease self-immunity L-fibroin PF05849.6 EAQ92301.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) ketoacyl-synt PF00109.21 EAQ92307.1 - 9.6e-72 241.5 0.0 1.8e-71 240.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAQ92307.1 - 1.8e-51 175.4 0.0 3e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 EAQ92307.1 - 4.8e-41 141.4 0.2 2.1e-39 136.1 0.0 2.7 3 0 0 3 3 3 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 EAQ92307.1 - 8.2e-36 122.4 0.3 1.9e-35 121.2 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EAQ92307.1 - 7.9e-20 70.8 3.3 9.1e-09 35.4 0.1 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 EAQ92307.1 - 3.6e-17 62.4 0.0 8.8e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EAQ92307.1 - 1.6e-08 34.7 0.8 0.00095 19.0 0.0 3.7 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ92307.1 - 1.6e-06 27.9 0.0 0.1 12.3 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EAQ92307.1 - 0.0017 17.4 0.1 0.0054 15.7 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Cu-oxidase_2 PF07731.9 EAQ92308.1 - 2.5e-39 133.9 11.2 1.8e-36 124.6 1.4 3.9 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAQ92308.1 - 1.3e-37 128.0 10.6 2.2e-34 117.7 0.7 4.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EAQ92308.1 - 2.4e-20 73.0 3.5 9e-19 67.9 0.4 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EAQ92308.1 - 0.0015 18.3 0.0 11 6.0 0.0 3.7 3 0 0 3 3 3 2 Cupredoxin-like domain DNA_pol_E_B PF04042.11 EAQ92309.1 - 2.2e-66 223.0 0.0 4.3e-66 222.1 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B PC4 PF02229.11 EAQ92310.1 - 3.1e-19 67.9 0.0 6.1e-19 66.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.10 EAQ92311.1 - 1.7e-37 128.7 1.9 1.8e-37 128.7 0.0 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EAQ92311.1 - 1.1e-21 76.9 0.1 1.1e-21 76.9 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EAQ92311.1 - 2.6e-07 30.4 0.0 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 PX domain MFS_1 PF07690.11 EAQ92312.1 - 1.6e-14 53.4 14.2 2.2e-14 52.9 8.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sensor PF13796.1 EAQ92312.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 2.9 3 1 0 3 3 3 1 Putative sensor ADIP PF11559.3 EAQ92313.1 - 5.5e-36 123.7 5.6 5.5e-36 123.7 3.9 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding IncA PF04156.9 EAQ92313.1 - 5.6 6.5 9.5 0.28 10.7 2.6 1.7 2 0 0 2 2 2 0 IncA protein RRP7 PF12923.2 EAQ92314.1 - 1.8e-23 82.9 14.6 2.3e-23 82.6 10.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) MOSC PF03473.12 EAQ92315.1 - 5.4e-16 58.2 0.0 1.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EAQ92315.1 - 7.2e-08 32.0 4.0 1.7e-07 30.8 2.8 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain F-box PF00646.28 EAQ92316.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain BAR PF03114.13 EAQ92317.1 - 5.5e-66 222.3 6.4 6.8e-66 222.0 4.4 1.1 1 0 0 1 1 1 1 BAR domain APG6 PF04111.7 EAQ92317.1 - 3.9 6.4 9.0 4.2 6.3 4.6 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_5 PF00266.14 EAQ92318.1 - 6.4e-85 285.1 0.0 3.9e-79 266.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAQ92318.1 - 1.4e-08 34.2 0.0 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EAQ92318.1 - 4.5e-07 29.2 0.0 2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EAQ92318.1 - 0.0023 16.4 0.1 0.016 13.6 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EAQ92318.1 - 0.029 12.6 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CsbD PF05532.7 EAQ92319.1 - 9.7e-07 28.3 22.5 4.2e-06 26.3 0.8 3.2 2 1 1 3 3 3 3 CsbD-like NmrA PF05368.8 EAQ92321.1 - 3.4e-12 46.1 0.0 1.5e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAQ92321.1 - 0.0011 18.9 0.0 0.0044 17.0 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EAQ92321.1 - 0.047 12.6 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase A_deaminase PF00962.17 EAQ92322.1 - 6.1e-18 64.8 0.0 1.6e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase DAO PF01266.19 EAQ92323.1 - 4.6e-45 154.0 3.3 5.9e-45 153.7 2.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ92323.1 - 0.0013 18.6 1.1 0.0028 17.6 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAQ92323.1 - 0.0023 18.0 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ92323.1 - 0.0072 15.4 1.8 0.012 14.7 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ92323.1 - 0.087 12.6 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase eIF-5_eIF-2B PF01873.12 EAQ92324.1 - 2.8e-44 149.7 0.2 4.6e-44 149.0 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EAQ92324.1 - 0.092 13.0 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar DNA_RNApol_7kD PF03604.8 EAQ92324.1 - 0.16 11.4 1.2 0.39 10.2 0.8 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 EAQ92324.1 - 3.5 7.8 7.5 2 8.6 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain PNGaseA PF12222.3 EAQ92326.1 - 2.4e-135 451.7 1.5 3e-135 451.4 1.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 EAQ92327.1 - 8.7e-12 45.1 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AIM24 PF01987.12 EAQ92328.1 - 6.7e-54 182.5 0.0 8.2e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 TPR_11 PF13414.1 EAQ92330.1 - 0.12 12.0 4.9 1.9 8.1 1.3 2.4 2 0 0 2 2 2 0 TPR repeat Pkinase PF00069.20 EAQ92332.1 - 2.7e-58 197.1 0.0 3.6e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92332.1 - 1.6e-21 76.5 0.5 2.7e-21 75.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EAQ92332.1 - 0.003 17.3 0.0 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ92332.1 - 0.0087 15.6 0.7 0.021 14.4 0.4 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pex24p PF06398.6 EAQ92334.1 - 2.2e-88 296.4 4.7 3e-59 200.6 0.0 2.0 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin CsgF PF10614.4 EAQ92334.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein DUF3292 PF11696.3 EAQ92334.1 - 0.26 9.1 4.1 0.81 7.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) DUF639 PF04842.7 EAQ92334.1 - 0.3 9.2 0.2 0.44 8.6 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) polyprenyl_synt PF00348.12 EAQ92335.1 - 8.2e-43 146.1 0.0 9.7e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Fez1 PF06818.10 EAQ92335.1 - 0.23 11.4 0.1 0.39 10.7 0.1 1.2 1 0 0 1 1 1 0 Fez1 CDC14 PF08045.6 EAQ92336.1 - 7.1e-83 277.6 0.0 8.5e-83 277.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component nec1 PF10379.4 EAQ92337.1 - 0.07 12.3 1.8 0.11 11.7 1.3 1.4 1 0 0 1 1 1 0 Virulence protein nec1 Aldedh PF00171.17 EAQ92339.1 - 1.4e-14 53.3 9.0 7.5e-10 37.7 4.3 2.6 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Kinetocho_Slk19 PF12709.2 EAQ92340.1 - 2.7e-19 69.0 7.2 2.7e-19 69.0 5.0 3.9 3 1 1 4 4 4 2 Central kinetochore-associated FlaC_arch PF05377.6 EAQ92340.1 - 0.79 9.6 20.4 0.032 14.1 1.2 4.9 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.2 EAQ92340.1 - 7.2 6.4 32.2 0.44 10.3 8.2 3.0 1 1 1 2 2 2 0 Tropomyosin like KilA-N PF04383.8 EAQ92341.1 - 0.00015 21.3 0.0 0.0025 17.4 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain PTCB-BRCT PF12738.2 EAQ92344.1 - 9.5e-06 25.3 0.2 4.6e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EAQ92344.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AMP-binding PF00501.23 EAQ92345.1 - 3.1e-77 259.7 0.0 3.7e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ92345.1 - 2.9e-16 60.1 0.3 8.3e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SerH PF06873.6 EAQ92346.1 - 0.0058 15.2 2.6 0.0063 15.1 1.8 1.0 1 0 0 1 1 1 1 Cell surface immobilisation antigen SerH ADH_zinc_N PF00107.21 EAQ92347.1 - 1.5e-22 79.5 0.0 2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ92347.1 - 9.8e-18 65.2 0.7 2.9e-16 60.5 0.2 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ92347.1 - 6.1e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DLH PF01738.13 EAQ92348.1 - 8.2e-16 57.9 0.0 6.7e-13 48.4 0.0 2.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAQ92348.1 - 6.3e-09 35.7 0.1 9.6e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ92348.1 - 1.4e-06 28.3 0.4 0.00018 21.4 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAQ92348.1 - 0.0067 16.0 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold LAT PF15234.1 EAQ92348.1 - 0.14 11.5 6.4 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells DUF1180 PF06679.7 EAQ92348.1 - 9.2 6.1 7.2 4.1 7.2 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) KIAA1328 PF15369.1 EAQ92349.1 - 3.8 7.2 8.3 6.9 6.3 5.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 MBF1 PF08523.5 EAQ92350.1 - 7.5e-23 80.3 1.5 1.4e-22 79.4 1.0 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EAQ92350.1 - 2.6e-11 43.1 0.0 4.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EAQ92350.1 - 2.2e-05 24.5 0.0 3e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EAQ92350.1 - 0.00024 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 EAQ92350.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1365 PF07103.6 EAQ92351.1 - 1.3e-36 125.9 0.0 1.9e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF702 PF05142.7 EAQ92351.1 - 1.3 9.1 2.8 3.1 7.9 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) GFA PF04828.9 EAQ92352.1 - 1.7e-11 43.9 0.0 2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_18 PF00704.23 EAQ92353.1 - 8.4e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 INO80_Ies4 PF08193.6 EAQ92355.1 - 2e-84 283.0 22.4 2.4e-84 282.7 15.5 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 EAQ92357.1 - 9.8e-16 57.7 0.1 7.2e-15 54.9 0.0 2.0 1 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EAQ92357.1 - 7.1e-15 55.1 0.0 1.8e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 SPRY domain LisH PF08513.6 EAQ92357.1 - 2e-05 24.1 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 LisH DUF2731 PF10806.3 EAQ92358.1 - 0.00034 20.8 0.2 0.0011 19.2 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 EAQ92358.1 - 0.00056 19.7 0.0 0.0018 18.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ92358.1 - 0.0018 18.7 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetyltransf_10 PF13673.1 EAQ92358.1 - 0.085 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_11 PF14833.1 EAQ92359.1 - 0.079 13.0 0.1 0.086 12.9 0.1 1.1 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase adh_short PF00106.20 EAQ92360.1 - 2.7e-09 37.1 1.0 4.9e-09 36.3 0.7 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ92360.1 - 0.023 14.3 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 KR domain Chitin_synth_1 PF01644.12 EAQ92361.1 - 6.7e-71 237.3 0.0 9.9e-71 236.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EAQ92361.1 - 1.3e-26 93.0 0.0 5.2e-22 77.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EAQ92361.1 - 1.5e-26 91.8 0.1 2.8e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 EAQ92361.1 - 1.7e-08 34.5 0.0 1.4e-07 31.5 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EAQ92361.1 - 7.3e-08 32.3 10.7 7.3e-08 32.3 7.4 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Syndecan PF01034.15 EAQ92363.1 - 0.0085 15.7 0.4 0.019 14.6 0.3 1.5 1 0 0 1 1 1 1 Syndecan domain Ras PF00071.17 EAQ92366.1 - 8e-51 171.6 0.0 1.5e-50 170.7 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EAQ92366.1 - 3.4e-17 63.0 0.1 2.2e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAQ92366.1 - 0.00046 19.4 0.0 0.0012 18.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAQ92366.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ92366.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ92366.1 - 0.058 12.6 0.0 0.69 9.1 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 EAQ92366.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 EAQ92368.1 - 4e-22 79.2 0.0 5.8e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAQ92368.1 - 2.7e-06 27.9 0.3 3e-05 24.5 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ92368.1 - 7.4e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like G_glu_transpept PF01019.16 EAQ92368.1 - 0.09 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Mcp5_PH PF12814.2 EAQ92370.1 - 7.9e-47 158.2 0.0 1.7e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology YkyA PF10368.4 EAQ92370.1 - 0.0023 17.3 11.1 0.0042 16.4 7.7 1.3 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein WEMBL PF05701.6 EAQ92370.1 - 0.26 9.7 21.8 0.48 8.8 15.1 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DivIC PF04977.10 EAQ92370.1 - 1.3 8.6 4.5 2.1 7.9 0.0 2.4 1 1 1 2 2 2 0 Septum formation initiator PALP PF00291.20 EAQ92371.1 - 3.9e-09 36.1 0.0 4.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IDO PF01231.13 EAQ92372.1 - 8.1e-08 31.1 0.0 9.1e-08 30.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase SpoU_methylase PF00588.14 EAQ92374.1 - 2.3e-28 98.8 0.0 3.7e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-PHD-like PF15446.1 EAQ92375.1 - 1.6e-74 248.9 16.3 2.9e-74 248.1 11.3 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EAQ92375.1 - 1.6e-54 184.7 0.0 2.3e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ92375.1 - 3e-14 52.6 0.0 8.9e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ92375.1 - 6.1e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.19 EAQ92375.1 - 0.0011 18.6 6.8 0.017 14.8 0.2 4.0 4 0 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EAQ92375.1 - 0.0014 18.2 8.9 0.0014 18.2 6.1 3.9 2 2 1 3 3 3 1 PHD-finger AAA_22 PF13401.1 EAQ92375.1 - 0.021 14.9 0.0 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PCI PF01399.22 EAQ92380.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 PCI domain Rep_fac-A_C PF08646.5 EAQ92381.1 - 9.2e-45 151.9 9.5 2.8e-43 147.1 3.0 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EAQ92381.1 - 2.5e-20 72.1 0.0 5.1e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EAQ92381.1 - 1.8e-17 62.9 1.2 1.7e-12 46.9 0.0 4.5 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 EAQ92381.1 - 0.0021 18.1 0.2 0.014 15.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF223 Amidohydro_2 PF04909.9 EAQ92382.1 - 9.8e-23 81.0 1.5 1.2e-22 80.8 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.23 EAQ92385.1 - 1.9e-19 69.1 0.2 2.2e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CBM_20 PF00686.14 EAQ92388.1 - 0.0065 16.0 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain DUF3827 PF12877.2 EAQ92388.1 - 0.6 8.1 4.1 1 7.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Phage_Coat_B PF05356.6 EAQ92389.1 - 0.0015 18.1 0.5 0.0055 16.3 0.0 2.1 3 0 0 3 3 3 1 Phage Coat protein B HD PF01966.17 EAQ92390.1 - 9.5e-07 28.8 0.9 1.7e-06 28.0 0.7 1.4 1 0 0 1 1 1 1 HD domain Cyclase_polyket PF04673.7 EAQ92390.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Polyketide synthesis cyclase EMP24_GP25L PF01105.19 EAQ92394.1 - 1.6e-40 138.7 0.0 2e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.11 EAQ92395.1 - 2.1e-23 81.7 0.2 4.2e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase ASFV_J13L PF05568.6 EAQ92395.1 - 0.35 10.3 1.3 0.35 10.4 0.2 1.6 2 0 0 2 2 2 0 African swine fever virus J13L protein MIS13 PF08202.6 EAQ92396.1 - 1.4e-62 211.5 0.0 4.5e-62 209.8 0.0 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Pox_Ag35 PF03286.9 EAQ92396.1 - 3.2 7.2 6.1 4.8 6.6 3.8 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Aft1_HRA PF11786.3 EAQ92397.1 - 3.3e-32 110.5 9.6 3.3e-32 110.5 6.6 2.6 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.3 EAQ92397.1 - 7.3e-30 103.8 7.2 7.3e-30 103.8 5.0 5.0 3 2 1 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 EAQ92397.1 - 1e-20 73.9 10.3 1e-20 73.9 7.2 4.2 6 0 0 6 6 6 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EAQ92397.1 - 7e-11 41.9 5.0 7e-11 41.9 3.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ92397.1 - 4.2e-05 23.2 8.3 4.2e-05 23.2 5.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EAQ92397.1 - 0.00041 20.5 2.1 0.00041 20.5 1.4 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor U79_P34 PF03064.11 EAQ92397.1 - 7.1 6.0 15.7 12 5.3 10.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GST_C_2 PF13410.1 EAQ92399.1 - 0.0032 17.3 3.1 0.0089 15.9 2.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAQ92399.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fork_head PF00250.13 EAQ92400.1 - 2e-12 46.9 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EAQ92400.1 - 0.0002 21.3 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain KIAA1328 PF15369.1 EAQ92400.1 - 0.048 13.4 0.0 0.048 13.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein KIAA1328 DUF4231 PF14015.1 EAQ92401.1 - 0.029 14.3 1.5 0.073 13.0 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3671 PF12420.3 EAQ92401.1 - 0.33 10.9 1.4 0.57 10.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function m04gp34like PF12216.3 EAQ92401.1 - 0.41 9.9 0.1 0.74 9.1 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein SUR7 PF06687.7 EAQ92402.1 - 2.3e-30 105.7 5.4 3.3e-30 105.2 3.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EAQ92402.1 - 0.00018 21.2 3.5 0.00018 21.2 2.4 2.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3169 PF11368.3 EAQ92402.1 - 0.086 12.0 0.1 0.086 12.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) Cation_efflux PF01545.16 EAQ92402.1 - 0.092 11.7 3.2 0.15 11.0 2.2 1.5 1 1 0 1 1 1 0 Cation efflux family DC_STAMP PF07782.8 EAQ92402.1 - 0.2 11.2 0.1 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 DC-STAMP-like protein DUF2207 PF09972.4 EAQ92402.1 - 0.65 8.5 5.4 1.7 7.1 3.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Yip1 PF04893.12 EAQ92402.1 - 0.74 9.2 14.4 0.16 11.4 7.0 1.8 2 0 0 2 2 2 0 Yip1 domain DUF4231 PF14015.1 EAQ92402.1 - 6.5 6.7 8.2 2.6 8.0 1.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) Bacteriocin_IIc PF10439.4 EAQ92402.1 - 9.7 6.4 9.2 0.73 10.0 2.8 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide TRP PF06011.7 EAQ92408.1 - 4.4e-152 506.6 28.1 5.3e-152 506.3 19.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAQ92408.1 - 4.2e-42 143.5 0.2 6.5e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 ML-like domain VirB3 PF05101.8 EAQ92408.1 - 0.58 10.1 7.3 5.2 7.1 0.0 3.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein DUF3433 PF11915.3 EAQ92410.1 - 4.4e-48 161.3 13.8 2.3e-26 91.7 0.7 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Miro PF08477.8 EAQ92411.1 - 0.00033 21.1 0.0 0.23 11.9 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein G-alpha PF00503.15 EAQ92411.1 - 0.0038 15.9 0.5 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 G-protein alpha subunit Ras PF00071.17 EAQ92411.1 - 0.014 14.7 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Ras family Pex14_N PF04695.8 EAQ92411.1 - 0.26 11.3 4.3 0.55 10.2 3.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M48 PF01435.13 EAQ92412.1 - 5.7e-35 120.9 0.0 8.4e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Mitofilin PF09731.4 EAQ92413.1 - 7.4 5.1 24.1 11 4.5 16.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SKG6 PF08693.5 EAQ92414.1 - 0.0014 17.8 5.5 0.0014 17.8 3.8 1.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Cir_N PF10197.4 EAQ92414.1 - 0.041 13.9 1.4 0.058 13.4 1.0 1.2 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF4448 PF14610.1 EAQ92414.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) bZIP_1 PF00170.16 EAQ92415.1 - 1e-08 34.9 1.6 1e-08 34.9 1.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ92415.1 - 4.8e-05 23.0 2.6 4.8e-05 23.0 1.8 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EAQ92415.1 - 0.0064 16.7 5.1 0.014 15.6 3.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor TPR_12 PF13424.1 EAQ92416.1 - 1.5e-06 28.0 0.1 3.2e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ92416.1 - 3.3e-05 23.6 0.1 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ92416.1 - 4.6e-05 23.0 0.5 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ92416.1 - 0.00013 21.5 0.1 0.0003 20.3 0.1 1.7 1 1 0 1 1 1 1 TPR repeat PEGSRP PF07623.6 EAQ92416.1 - 0.0019 17.4 0.3 0.0039 16.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1584) TPR_1 PF00515.23 EAQ92416.1 - 0.0021 17.5 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ92416.1 - 0.088 12.6 0.1 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc5 PF12862.2 EAQ92416.1 - 0.13 12.0 0.1 0.21 11.4 0.1 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_16 PF13432.1 EAQ92416.1 - 0.61 10.8 9.2 0.22 12.2 0.8 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 EAQ92418.1 - 7.1e-06 26.0 2.4 7.1e-06 26.0 1.6 5.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ92418.1 - 0.00012 22.1 35.1 0.00016 21.7 0.7 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ92418.1 - 0.0012 18.9 16.0 0.01 15.9 0.1 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ92418.1 - 0.016 15.4 20.7 0.11 12.7 0.1 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAQ92418.1 - 0.025 14.5 4.2 0.21 11.5 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger AT_hook PF02178.14 EAQ92419.1 - 0.00077 18.8 17.2 0.034 13.7 3.6 2.9 2 0 0 2 2 2 2 AT hook motif DUF605 PF04652.11 EAQ92419.1 - 8.4 5.6 9.7 9.8 5.4 6.7 1.1 1 0 0 1 1 1 0 Vta1 like MULE PF10551.4 EAQ92420.1 - 7.1e-19 67.7 0.1 1.2e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ92420.1 - 2.8e-06 26.1 0.0 3.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Bradykinin PF06753.7 EAQ92421.1 - 2.9 7.4 7.8 0.44 10.0 1.3 2.7 2 0 0 2 2 2 0 Bradykinin PPR_2 PF13041.1 EAQ92423.1 - 1.9e-14 53.3 0.0 6.4e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 PPR repeat family PPR_1 PF12854.2 EAQ92423.1 - 1.6e-11 43.4 0.0 9.4e-09 34.6 0.0 2.7 2 0 0 2 2 2 2 PPR repeat PPR PF01535.15 EAQ92423.1 - 2.4e-07 30.2 0.2 6.8e-06 25.7 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 EAQ92423.1 - 2.9e-06 27.1 0.2 3.2e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain cwf18 PF08315.7 EAQ92424.1 - 2.6e-42 144.3 6.9 2.6e-42 144.3 4.8 2.1 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor JAB PF01398.16 EAQ92427.1 - 1.6e-16 60.0 0.0 2.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAQ92427.1 - 8.3e-14 51.6 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF1253 PF06862.7 EAQ92428.1 - 1.9e-164 547.3 0.1 2.5e-164 546.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Ribosomal_L17 PF01196.14 EAQ92429.1 - 1.6e-30 105.4 0.0 2.6e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Acyl_transf_3 PF01757.17 EAQ92431.1 - 8.7e-72 241.7 21.6 1.1e-71 241.4 14.9 1.1 1 0 0 1 1 1 1 Acyltransferase family ALAD PF00490.16 EAQ92432.1 - 3.5e-117 390.9 0.0 4e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DDE_1 PF03184.14 EAQ92433.1 - 2e-46 157.8 0.0 3.6e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GCR1_C PF12550.3 EAQ92433.1 - 2.8e-22 78.3 0.4 2.8e-22 78.3 0.3 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HTH_psq PF05225.11 EAQ92433.1 - 1.3e-13 50.2 0.2 3.1e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF904 PF06005.7 EAQ92433.1 - 1.2 9.4 5.5 0.62 10.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF3123 PF11321.3 EAQ92434.1 - 2.3 8.5 8.4 1.2 9.4 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Y_phosphatase3C PF13348.1 EAQ92436.1 - 6e-11 42.2 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase3 PF13350.1 EAQ92436.1 - 9.1e-08 32.5 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Radical_SAM PF04055.16 EAQ92436.1 - 0.06 13.5 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 Radical SAM superfamily Toxin_36 PF10550.4 EAQ92436.1 - 0.1 13.7 0.1 0.38 12.0 0.1 2.0 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin DUF2526 PF10735.4 EAQ92437.1 - 0.24 11.4 1.2 0.38 10.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2526) Ribosomal_S4 PF00163.14 EAQ92438.1 - 8.2e-13 48.5 2.3 1.7e-12 47.5 1.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EAQ92438.1 - 6.9e-11 41.4 0.1 2.4e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S18 PF01084.15 EAQ92439.1 - 2.6e-13 49.5 0.0 6.7e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_3 PF13812.1 EAQ92440.1 - 9.6e-10 37.9 0.2 0.0004 20.4 0.0 5.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 EAQ92440.1 - 4.8e-07 29.3 0.0 0.052 13.5 0.0 4.8 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.1 EAQ92440.1 - 0.00059 19.7 0.1 2.4 8.1 0.0 4.3 6 0 0 6 6 6 2 PPR repeat family FTA4 PF13093.1 EAQ92441.1 - 1.7e-68 230.2 0.0 1.9e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 LZ_Tnp_IS66 PF13007.2 EAQ92441.1 - 0.00011 22.8 1.4 0.00011 22.8 1.0 2.7 3 0 0 3 3 3 1 Transposase C of IS166 homeodomain Alkyl_sulf_dimr PF14863.1 EAQ92441.1 - 0.076 13.2 3.3 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation ArfGap PF01412.13 EAQ92442.1 - 6.6e-38 129.0 0.0 1.6e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 EAQ92442.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Methyltransf_23 PF13489.1 EAQ92443.1 - 8e-16 58.1 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ92443.1 - 7e-07 29.8 0.0 2e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ92443.1 - 1.2e-06 28.2 0.0 2.5e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ92443.1 - 2e-05 24.9 0.0 0.00013 22.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ92443.1 - 0.0087 15.4 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EAQ92443.1 - 0.011 15.7 0.0 0.044 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EAQ92443.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EAQ92443.1 - 0.039 14.3 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ92443.1 - 0.044 12.9 0.0 0.25 10.4 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EAQ92443.1 - 0.055 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 EAQ92443.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Pyridoxal_deC PF00282.14 EAQ92444.1 - 3.2e-05 22.5 0.0 0.00013 20.5 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain B5 PF03484.10 EAQ92444.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain ThiF PF00899.16 EAQ92445.1 - 3.2e-28 98.2 0.0 6.4e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family DUF2462 PF09495.5 EAQ92445.1 - 3.2e-06 27.8 5.5 6.6e-06 26.7 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Shikimate_DH PF01488.15 EAQ92445.1 - 0.025 14.7 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 EAQ92446.1 - 4.1e-26 90.6 1.1 6.2e-26 90.0 0.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EAQ92446.1 - 0.13 13.0 0.0 0.38 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain SCIMP PF15050.1 EAQ92447.1 - 0.13 12.1 1.2 8 6.3 0.1 2.5 2 1 0 2 2 2 0 SCIMP protein PMP1_2 PF08114.6 EAQ92447.1 - 0.16 11.5 0.3 0.34 10.4 0.2 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Glyco_hydro_61 PF03443.9 EAQ92448.1 - 2.3e-64 217.1 0.1 2.8e-64 216.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 2Fe-2S_thioredx PF01257.14 EAQ92449.1 - 2.8e-59 198.8 0.1 3.5e-59 198.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin HSP9_HSP12 PF04119.7 EAQ92449.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Heat shock protein 9/12 Kelch_3 PF13415.1 EAQ92450.1 - 8e-24 83.1 22.3 2.9e-05 24.1 0.1 8.4 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EAQ92450.1 - 4.1e-18 64.9 7.5 1.3e-05 25.0 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 EAQ92450.1 - 1.1e-16 60.3 22.3 5.9e-05 22.7 0.2 7.7 7 1 1 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EAQ92450.1 - 6.9e-16 57.6 5.2 1.5e-05 24.9 0.0 5.9 6 1 0 6 6 5 3 Kelch motif Kelch_1 PF01344.20 EAQ92450.1 - 6.7e-13 47.9 2.5 1.9e-05 24.1 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EAQ92450.1 - 2.3e-10 39.7 6.6 1.5e-05 24.5 0.1 5.5 5 1 0 5 5 5 1 Kelch motif DUF2457 PF10446.4 EAQ92450.1 - 0.011 14.5 17.1 0.02 13.6 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 EAQ92450.1 - 0.016 13.0 3.5 0.025 12.4 2.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EAQ92450.1 - 0.043 11.7 14.7 0.059 11.2 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 EAQ92450.1 - 0.18 12.3 16.3 0.41 11.2 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Daxx PF03344.10 EAQ92450.1 - 0.21 10.0 14.0 0.29 9.5 9.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EAQ92450.1 - 0.52 9.6 9.1 0.78 9.0 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Myc_N PF01056.13 EAQ92450.1 - 0.8 8.8 11.7 1.4 7.9 8.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 EAQ92450.1 - 1.1 8.9 7.5 2.1 8.0 5.2 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 EAQ92450.1 - 1.1 7.2 12.9 1.6 6.7 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EAQ92450.1 - 1.3 8.1 15.1 2.2 7.3 10.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.7 EAQ92450.1 - 2 7.6 14.2 3.1 6.9 9.8 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.6 EAQ92450.1 - 2.5 7.5 13.4 3.6 7.0 9.3 1.2 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.6 EAQ92450.1 - 2.7 7.7 10.9 4.9 6.9 7.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal TLP-20 PF06088.6 EAQ92450.1 - 2.9 7.5 8.0 4.6 6.8 5.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2722 PF10846.3 EAQ92450.1 - 3 6.7 9.2 4.4 6.2 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sigma70_ner PF04546.8 EAQ92450.1 - 3.1 7.3 18.5 5.4 6.5 12.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 EAQ92450.1 - 6.6 6.3 16.2 10 5.7 11.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IFT57 PF10498.4 EAQ92450.1 - 9.2 4.8 6.7 13 4.4 4.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NOA36 PF06524.7 EAQ92450.1 - 9.3 5.4 13.9 15 4.7 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein Ceramidase_alk PF04734.8 EAQ92451.1 - 1.3e-279 928.7 0.0 1.5e-279 928.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase OapA_N PF08525.6 EAQ92451.1 - 0.45 10.3 1.6 1.5 8.6 1.1 1.9 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif BCAS2 PF05700.6 EAQ92452.1 - 1.5e-28 99.7 0.0 2.3e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) cNMP_binding PF00027.24 EAQ92453.1 - 6.7e-25 86.7 0.0 7.1e-22 77.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CDC50 PF03381.10 EAQ92454.1 - 1.6e-93 312.9 0.4 2e-93 312.5 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 EAQ92455.1 - 8.3e-58 194.5 0.8 5.1e-57 191.9 0.1 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EAQ92455.1 - 2e-55 186.7 0.5 6e-55 185.2 0.3 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EAQ92455.1 - 6.3e-24 84.7 0.0 1.1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EAQ92455.1 - 2.3e-21 75.5 0.0 6.2e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Sensor PF13796.1 EAQ92459.1 - 0.11 12.1 5.3 0.37 10.3 0.4 2.1 2 0 0 2 2 2 0 Putative sensor GCS PF03074.11 EAQ92460.1 - 2.3e-154 513.9 0.0 8.8e-124 413.3 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase CFEM PF05730.6 EAQ92461.1 - 0.0034 17.1 1.5 0.0065 16.2 1.0 1.4 1 0 0 1 1 1 1 CFEM domain TMEM154 PF15102.1 EAQ92461.1 - 0.011 15.4 1.0 0.026 14.2 0.7 1.6 1 0 0 1 1 1 0 TMEM154 protein family DEAD PF00270.24 EAQ92462.1 - 7.2e-35 119.9 0.2 4.4e-34 117.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ92462.1 - 3.8e-22 77.9 0.0 8.3e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EAQ92462.1 - 0.00013 21.6 0.4 0.011 15.5 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain CMS1 PF14617.1 EAQ92462.1 - 0.0046 16.0 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 EAQ92462.1 - 0.0047 16.5 0.1 0.013 15.0 0.0 1.7 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EAQ92462.1 - 0.0098 15.8 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain FCH PF00611.18 EAQ92463.1 - 3.7e-21 75.1 3.1 5.4e-21 74.5 0.0 2.9 3 1 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EAQ92463.1 - 3.7e-15 55.2 0.1 1.5e-12 46.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EAQ92463.1 - 1.3e-14 53.6 5.6 2e-14 53.0 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EAQ92463.1 - 2.1e-05 23.7 0.1 9.6e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EAQ92463.1 - 0.054 12.9 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain Allexi_40kDa PF05549.6 EAQ92463.1 - 0.07 12.4 0.4 0.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein C1_2 PF03107.11 EAQ92463.1 - 0.52 10.4 7.8 0.9 9.7 5.4 1.4 1 0 0 1 1 1 0 C1 domain Glyco_hydro_72 PF03198.9 EAQ92464.1 - 4.4e-114 380.6 3.9 5.9e-114 380.2 2.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EAQ92464.1 - 1.7e-08 34.0 3.0 2.2e-07 30.3 2.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Coatomer_E PF04733.9 EAQ92467.1 - 4.1e-61 206.6 7.5 4.7e-61 206.5 5.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_15 PF13429.1 EAQ92467.1 - 1.5e-06 27.5 8.9 0.00012 21.2 1.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ92467.1 - 7.7e-06 25.9 3.0 0.79 9.8 0.1 3.9 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EAQ92467.1 - 6e-05 22.4 1.1 0.17 11.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ92467.1 - 9.3e-05 22.6 27.8 0.00078 19.7 1.3 4.3 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ92467.1 - 0.0001 22.8 28.7 0.00014 22.4 1.1 5.3 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ92467.1 - 0.00018 21.0 0.0 0.00018 21.0 0.0 4.1 2 1 3 5 5 5 1 TPR repeat TPR_14 PF13428.1 EAQ92467.1 - 0.00065 20.1 1.4 0.00065 20.1 0.9 6.5 5 3 1 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ92467.1 - 0.00084 18.9 0.1 0.66 9.8 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ92467.1 - 0.0012 19.2 8.7 1.1 9.8 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Type_III_YscG PF09477.5 EAQ92467.1 - 0.0035 17.4 8.8 0.023 14.7 0.4 3.8 1 1 2 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_12 PF13424.1 EAQ92467.1 - 0.0078 16.1 12.8 0.014 15.2 0.5 4.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ92467.1 - 0.017 15.0 0.0 0.017 15.0 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ92467.1 - 0.06 13.7 1.5 0.06 13.7 1.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ92467.1 - 0.31 10.9 0.1 0.31 10.9 0.1 5.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ92467.1 - 0.41 10.9 4.0 65 4.0 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ92467.1 - 2.2 8.2 15.3 0.34 10.7 0.2 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat PS_Dcarbxylase PF02666.10 EAQ92468.1 - 1.4e-52 177.9 0.0 2e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EAQ92468.1 - 2.8e-25 87.9 0.0 2.9e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EAQ92468.1 - 0.0022 18.1 0.2 0.0058 16.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EAQ92468.1 - 0.0029 16.7 0.0 0.014 14.6 0.0 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EAQ92468.1 - 0.034 14.0 0.0 0.19 11.6 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 EAQ92468.1 - 0.085 12.2 0.1 0.47 9.8 0.0 2.4 2 0 0 2 2 2 0 EF hand DAO PF01266.19 EAQ92469.1 - 5.6e-18 64.9 0.1 2.9e-16 59.3 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAQ92469.1 - 0.048 13.4 0.1 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3405 PF11885.3 EAQ92470.1 - 2.4e-184 613.2 2.2 2.4e-184 613.2 1.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) LIM PF00412.17 EAQ92472.1 - 1.4e-21 76.2 10.4 5.3e-12 45.6 1.7 2.2 2 0 0 2 2 2 2 LIM domain RE_ApaLI PF09499.5 EAQ92472.1 - 0.36 10.1 0.1 0.58 9.4 0.1 1.2 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease C1_3 PF07649.7 EAQ92472.1 - 3.3 7.8 14.5 1.8 8.6 0.6 3.7 4 0 0 4 4 4 0 C1-like domain Inos-1-P_synth PF01658.12 EAQ92473.1 - 8.6e-46 154.3 0.5 1.3e-45 153.8 0.4 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.7 EAQ92473.1 - 3.2e-23 82.6 0.0 8.4e-23 81.2 0.0 1.6 1 1 1 2 2 2 1 Myo-inositol-1-phosphate synthase FBPase_2 PF06874.6 EAQ92473.1 - 0.045 11.7 0.0 0.067 11.2 0.0 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase AMP-binding PF00501.23 EAQ92474.1 - 3.1e-82 276.2 0.0 4.1e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ92474.1 - 1.5e-12 48.2 1.5 2.9e-12 47.3 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EAQ92476.1 - 5.7e-20 71.3 53.9 6.2e-13 48.1 13.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ92476.1 - 2e-13 49.7 32.1 1.4e-09 37.1 14.0 3.1 1 1 1 2 2 2 2 Sugar (and other) transporter DnaJ PF00226.26 EAQ92477.1 - 1.6e-12 46.9 0.0 2.5e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pectate_lyase_3 PF12708.2 EAQ92478.1 - 1.1e-17 64.8 5.8 1.5e-17 64.4 1.6 2.7 3 0 0 3 3 3 1 Pectate lyase superfamily protein NosD PF05048.8 EAQ92478.1 - 4.6e-08 32.5 1.0 1.4e-07 30.8 0.7 1.8 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 EAQ92478.1 - 1.7e-07 31.0 5.7 7.3e-07 29.0 3.9 2.0 2 0 0 2 2 2 1 Right handed beta helix region Adeno_E1B_55K PF01696.12 EAQ92478.1 - 8.1e-05 21.2 0.9 0.00012 20.7 0.6 1.2 1 0 0 1 1 1 1 Adenovirus EB1 55K protein / large t-antigen SCP2 PF02036.12 EAQ92479.1 - 2.3e-24 85.6 0.3 2.9e-24 85.2 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EAQ92479.1 - 8.7e-07 28.9 0.1 1.1e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EAQ92479.1 - 0.0063 15.9 0.0 0.0072 15.7 0.0 1.1 1 0 0 1 1 1 1 Sterol carrier protein domain DUF3319 PF11782.3 EAQ92479.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) Ran_BP1 PF00638.13 EAQ92480.1 - 2.3e-11 43.8 0.0 1.1e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EAQ92480.1 - 5.2e-10 39.5 61.5 5.9e-07 29.7 21.4 9.6 2 1 4 6 6 6 2 Nucleoporin FG repeat region Tbf5 PF06331.7 EAQ92482.1 - 9.7e-22 76.5 1.9 1.3e-21 76.1 1.3 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CmcI PF04989.7 EAQ92482.1 - 0.059 12.6 0.6 0.074 12.3 0.4 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase ECH PF00378.15 EAQ92483.1 - 1.2e-39 135.9 1.4 2.3e-39 134.9 1.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TIM-br_sig_trns PF09370.5 EAQ92483.1 - 0.0021 17.1 0.1 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 TIM-barrel signal transduction protein ECH_C PF13766.1 EAQ92483.1 - 0.0046 17.0 0.1 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region SAM_2 PF07647.12 EAQ92484.1 - 4.5e-13 48.8 0.0 7.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EAQ92484.1 - 2.1e-12 46.2 0.0 4.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAQ92484.1 - 1.1e-11 44.1 0.0 2.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EAQ92484.1 - 2.7e-07 30.7 0.0 7.1e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 EAQ92484.1 - 4e-06 26.2 0.0 8.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EAQ92484.1 - 3.6e-05 23.9 0.0 9.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EAQ92484.1 - 0.053 13.5 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Gastrin PF00918.12 EAQ92484.1 - 0.098 13.4 2.9 0.32 11.8 0.0 3.1 2 1 1 3 3 3 0 Gastrin/cholecystokinin family SAM_1 PF00536.25 EAQ92484.1 - 0.11 12.6 0.1 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nucleopor_Nup85 PF07575.8 EAQ92485.1 - 2e-12 46.1 0.0 2.3e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.9 EAQ92485.1 - 0.34 8.9 0.9 0.49 8.4 0.0 1.6 2 0 0 2 2 2 0 Nup93/Nic96 DUF952 PF06108.7 EAQ92486.1 - 2.3e-11 43.4 0.0 1.3e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF952) ADH_N PF08240.7 EAQ92487.1 - 4e-29 100.5 1.4 8.8e-29 99.4 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ92487.1 - 1.1e-19 70.2 0.3 2.1e-19 69.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EAQ92487.1 - 0.015 14.6 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EAQ92487.1 - 0.095 12.6 0.9 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 EAQ92487.1 - 0.36 10.6 3.3 2.2 8.0 1.2 2.3 1 1 0 2 2 2 0 ThiF family zf-AN1 PF01428.11 EAQ92489.1 - 2.4e-11 43.3 11.7 3.3e-11 42.8 8.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EAQ92489.1 - 0.89 9.8 7.6 0.72 10.1 4.3 1.6 1 1 1 2 2 2 0 Tc5 transposase C-terminal domain DUF676 PF05057.9 EAQ92490.1 - 3.6e-53 180.1 0.0 6.5e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAQ92490.1 - 6.1e-07 29.3 0.0 1.7e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ92490.1 - 1.1e-06 28.7 0.1 5.3e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family HHH PF00633.18 EAQ92490.1 - 1.6e-06 27.5 0.0 3.9e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 EAQ92490.1 - 0.0009 19.4 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Lipase_2 PF01674.13 EAQ92490.1 - 0.0083 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) PGAP1 PF07819.8 EAQ92490.1 - 0.015 14.8 0.1 0.034 13.7 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EAQ92490.1 - 0.053 13.1 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) FAD_binding_6 PF00970.19 EAQ92490.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2793 PF10983.3 EAQ92491.1 - 0.021 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) GDPD PF03009.12 EAQ92492.1 - 3.3e-32 112.0 0.0 1.4e-31 109.9 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EAQ92492.1 - 0.00073 19.6 1.3 0.0016 18.5 0.4 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.13 EAQ92493.1 - 3.4e-30 104.8 0.0 6.1e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ92493.1 - 2.2e-10 40.2 11.1 4.2e-10 39.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EAQ92494.1 - 0.00027 21.2 0.0 0.0014 18.9 0.0 2.2 1 1 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.5 EAQ92495.1 - 3.3e-33 114.1 0.0 6.7e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EAQ92495.1 - 1.4e-14 54.0 0.0 2.9e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ92495.1 - 1.5e-05 24.3 0.0 0.00052 19.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ92495.1 - 0.0087 15.8 2.1 0.18 11.6 0.4 2.9 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 EAQ92495.1 - 0.0094 15.4 0.0 0.55 9.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EAQ92495.1 - 0.024 14.9 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 EAQ92495.1 - 0.046 12.8 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 EAQ92495.1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 AIG1 family tRNA-synt_2b PF00587.20 EAQ92496.1 - 3.8e-30 104.7 0.0 6.2e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAQ92496.1 - 3.3e-08 33.3 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 EAQ92497.1 - 1.7e-48 164.1 0.0 1.7e-48 164.1 0.0 2.6 4 0 0 4 4 4 1 CBF/Mak21 family 4HBT PF03061.17 EAQ92498.1 - 1.5e-09 37.8 0.0 2.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily V-ATPase_C PF03223.10 EAQ92499.1 - 2.4e-70 237.3 0.1 2.8e-70 237.1 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C AT_hook PF02178.14 EAQ92500.1 - 4.6 7.2 20.0 6 6.8 4.1 3.1 2 0 0 2 2 2 0 AT hook motif F-box PF00646.28 EAQ92501.1 - 3.6e-06 26.4 0.5 7.6e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAQ92501.1 - 0.0012 18.5 0.2 0.0036 16.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like SH3_9 PF14604.1 EAQ92503.1 - 2.1e-30 104.0 3.0 1.5e-14 53.2 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EAQ92503.1 - 3.9e-25 86.9 5.0 7.1e-12 44.5 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EAQ92503.1 - 2.6e-16 58.8 0.0 1.6e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EAQ92503.1 - 8.5e-11 41.8 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.19 EAQ92505.1 - 4e-18 65.1 0.0 1.8e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EAQ92505.1 - 4.6e-15 55.1 0.0 1.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAQ92505.1 - 0.0029 17.7 0.0 0.7 10.1 0.0 3.5 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAQ92505.1 - 0.0048 16.9 0.0 2.1 8.5 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Fungal_trans PF04082.13 EAQ92506.1 - 2.4e-21 75.7 0.3 4.2e-21 74.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase PF00128.19 EAQ92507.1 - 2e-46 158.8 0.2 8.9e-28 97.5 0.0 3.1 1 1 0 3 3 3 3 Alpha amylase, catalytic domain DUF1966 PF09260.6 EAQ92507.1 - 3.3e-29 100.8 0.0 6.2e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Fe-ADH PF00465.14 EAQ92508.1 - 0.015 13.9 0.3 0.029 13.0 0.1 1.5 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase K_channel_TID PF07941.6 EAQ92508.1 - 0.59 10.3 10.2 1.3 9.2 6.7 1.8 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain F-box PF00646.28 EAQ92509.1 - 0.0006 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAQ92509.1 - 0.0048 16.5 0.2 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like PIF1 PF05970.9 EAQ92510.1 - 1.9e-18 66.5 0.1 3.7e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase HTH_psq PF05225.11 EAQ92510.1 - 1.2e-13 50.3 0.2 2.7e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ92510.1 - 1.1e-09 37.8 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain AAA_30 PF13604.1 EAQ92510.1 - 0.00019 21.0 0.1 0.00061 19.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ92510.1 - 0.0002 21.4 0.0 0.00065 19.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ92510.1 - 0.028 14.5 0.0 0.099 12.7 0.0 2.0 1 0 0 1 1 1 0 Helicase associated domain Pectate_lyase_3 PF12708.2 EAQ92511.1 - 1.6e-66 224.6 12.8 1.3e-51 175.9 2.1 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EAQ92511.1 - 5.2e-06 25.8 4.6 0.017 14.5 0.1 2.8 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.1 EAQ92511.1 - 0.0011 19.1 0.1 0.004 17.2 0.0 2.0 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF2613 PF11021.3 EAQ92511.1 - 1.2 8.9 8.5 0.11 12.2 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) CFEM PF05730.6 EAQ92512.1 - 6.3e-34 115.6 30.3 8.7e-14 51.0 3.7 5.3 5 0 0 5 5 5 3 CFEM domain Chitin_bind_1 PF00187.14 EAQ92512.1 - 0.0052 16.7 20.6 0.0052 16.7 14.3 7.7 8 2 1 9 9 9 1 Chitin recognition protein UPF0444 PF15475.1 EAQ92512.1 - 0.11 12.5 5.1 2.4 8.2 0.3 3.3 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 DUF822 PF05687.8 EAQ92512.1 - 0.57 10.5 4.7 1.1 9.6 3.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Macoilin PF09726.4 EAQ92512.1 - 1.1 7.5 3.6 1.2 7.3 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 EAQ92512.1 - 2.4 8.2 8.1 4.3 7.3 5.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNA_pol_viral_N PF00242.12 EAQ92512.1 - 6 5.7 10.6 10 5.0 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ABC_tran PF00005.22 EAQ92513.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.27 EAQ92514.1 - 5.8e-89 289.1 33.2 4e-14 51.8 0.4 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EAQ92514.1 - 3.4e-10 39.9 0.0 2.6e-05 23.9 0.0 3.1 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAQ92514.1 - 4.5e-09 34.7 3.6 0.0011 16.9 1.3 2.6 1 1 1 2 2 2 2 IKI3 family Nup160 PF11715.3 EAQ92514.1 - 5.4e-07 28.1 13.2 0.036 12.2 0.0 5.5 2 2 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 EAQ92514.1 - 8.2e-05 22.1 12.5 5.9 6.6 0.1 5.7 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EAQ92514.1 - 0.00011 21.4 2.2 3.6 6.6 0.0 4.4 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EAQ92514.1 - 0.00012 20.5 0.0 0.012 13.9 0.0 2.9 2 2 1 3 3 3 1 Cytochrome D1 heme domain DUF3312 PF11768.3 EAQ92514.1 - 0.003 15.8 0.0 0.7 8.0 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EAQ92514.1 - 0.12 11.0 2.5 1.3 7.6 0.7 3.0 1 1 0 2 2 2 0 Nup133 N terminal like Myb_DNA-bind_6 PF13921.1 EAQ92515.1 - 0.00015 21.7 0.1 0.00027 20.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAQ92515.1 - 0.014 15.4 0.3 0.031 14.3 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cut8_N PF14482.1 EAQ92515.1 - 0.31 11.0 3.8 0.21 11.6 0.9 2.1 2 0 0 2 2 2 0 Cut8 proteasome-binding domain PBP1_TM PF14812.1 EAQ92515.1 - 5 7.5 7.4 5.6 7.3 3.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-B_box PF00643.19 EAQ92516.1 - 0.064 13.1 6.7 0.028 14.3 2.8 1.8 2 0 0 2 2 2 0 B-box zinc finger Spt5_N PF11942.3 EAQ92516.1 - 0.72 10.5 23.7 0.66 10.6 1.4 3.6 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal ABC_tran PF00005.22 EAQ92517.1 - 1.2e-52 177.9 0.0 1.6e-32 112.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAQ92517.1 - 7.8e-21 74.7 31.8 7e-16 58.4 13.1 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EAQ92517.1 - 7.1e-08 31.9 0.6 0.009 15.2 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EAQ92517.1 - 2.6e-06 26.9 2.4 0.84 9.0 0.6 3.8 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EAQ92517.1 - 6.2e-06 25.6 0.6 0.073 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ92517.1 - 9.1e-06 26.1 1.3 0.0043 17.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ92517.1 - 1.1e-05 25.5 1.6 0.058 13.3 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAQ92517.1 - 2e-05 24.7 0.2 3.8 7.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EAQ92517.1 - 0.0001 21.8 0.1 2.9 7.2 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 EAQ92517.1 - 0.00036 19.5 0.0 0.022 13.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 EAQ92517.1 - 0.00043 21.0 0.0 0.21 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EAQ92517.1 - 0.00097 19.1 0.0 8.6 6.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 EAQ92517.1 - 0.0011 18.8 6.0 0.023 14.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EAQ92517.1 - 0.0013 18.6 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EAQ92517.1 - 0.0035 17.6 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ92517.1 - 0.0039 16.3 0.1 0.67 9.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EAQ92517.1 - 0.0072 16.8 0.1 6.3 7.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 EAQ92517.1 - 0.01 14.9 0.5 5.8 5.9 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.7 EAQ92517.1 - 0.033 13.8 0.9 3.4 7.3 0.3 2.5 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 EAQ92517.1 - 0.035 14.0 0.0 4.2 7.3 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EAQ92517.1 - 0.036 12.8 0.2 0.17 10.5 0.0 2.0 2 0 0 2 2 2 0 ArgK protein DUF2075 PF09848.4 EAQ92517.1 - 0.22 10.4 0.8 1.7 7.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EAQ92517.1 - 0.45 9.3 1.8 3.4 6.4 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain adh_short PF00106.20 EAQ92518.1 - 3e-26 92.3 0.0 3.7e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ92518.1 - 3.4e-25 89.1 0.0 4.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ92518.1 - 1.4e-10 41.1 0.0 1.9e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ92518.1 - 0.0058 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAQ92518.1 - 0.0076 15.7 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EAQ92518.1 - 0.043 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cytochrom_C1 PF02167.10 EAQ92520.1 - 1.6e-82 276.4 0.0 1.9e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EAQ92520.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DAHP_synth_1 PF00793.15 EAQ92521.1 - 2.6e-98 328.0 0.0 3.2e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Mu-like_Pro PF10123.4 EAQ92521.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein Pro_isomerase PF00160.16 EAQ92522.1 - 9e-51 172.1 0.1 3.7e-50 170.1 0.0 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EAQ92522.1 - 5e-13 48.3 0.2 9.8e-08 31.6 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat FMN_dh PF01070.13 EAQ92523.1 - 1.2e-121 405.9 0.1 1.5e-121 405.6 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EAQ92523.1 - 0.00039 19.4 0.4 0.00061 18.8 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EAQ92523.1 - 0.00062 18.7 0.6 0.0064 15.4 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EAQ92523.1 - 0.0035 16.5 2.9 0.0055 15.8 2.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.16 EAQ92523.1 - 0.082 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase ThiG PF05690.9 EAQ92523.1 - 0.089 11.8 1.0 0.24 10.4 0.1 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EAQ92523.1 - 0.17 10.8 0.1 0.3 9.9 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Nup84_Nup100 PF04121.8 EAQ92524.1 - 2.2e-60 204.1 0.0 4.3e-59 199.8 0.0 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1903 PF08991.5 EAQ92525.1 - 1.3e-22 79.7 4.8 1.4e-22 79.5 3.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EAQ92525.1 - 0.00096 19.0 5.6 0.00096 19.0 3.9 1.7 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 EAQ92525.1 - 0.028 14.1 4.1 0.057 13.1 2.8 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUFB10 PF10249.4 EAQ92525.1 - 0.18 11.9 0.8 0.19 11.8 0.6 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Rad60-SLD PF11976.3 EAQ92526.1 - 2.9e-20 71.7 0.1 3.4e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAQ92526.1 - 2.1e-09 36.6 0.1 2.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family NAD_binding_8 PF13450.1 EAQ92526.1 - 0.011 15.7 0.1 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAQ92526.1 - 0.016 13.6 0.1 0.017 13.5 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EAQ92526.1 - 0.13 11.1 0.4 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain MepB PF08877.5 EAQ92526.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 MepB protein LIM PF00412.17 EAQ92527.1 - 7.3e-17 61.1 13.1 1.3e-08 34.7 3.8 2.5 2 0 0 2 2 2 2 LIM domain DUF2321 PF10083.4 EAQ92527.1 - 0.15 11.5 2.7 0.099 12.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.1 EAQ92527.1 - 6.6 6.5 16.5 1.9 8.2 0.5 4.7 5 0 0 5 5 5 0 Nudix N-terminal MFS_1 PF07690.11 EAQ92529.1 - 3.6e-16 58.8 39.0 2.2e-15 56.2 26.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ92529.1 - 8.8e-08 30.9 13.7 8.8e-08 30.9 9.5 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EAQ92529.1 - 0.0013 18.4 0.1 0.0044 16.7 0.0 1.9 1 0 0 1 1 1 1 MFS_1 like family Ligase_CoA PF00549.14 EAQ92530.1 - 6.9e-26 90.6 2.3 1.3e-15 57.3 0.0 3.4 2 1 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EAQ92530.1 - 1.9e-11 44.3 0.4 1.9e-11 44.3 0.2 2.8 4 1 0 4 4 4 1 CoA binding domain Succ_CoA_lig PF13607.1 EAQ92530.1 - 1.2e-08 34.6 0.4 2e-05 24.2 0.1 3.0 2 1 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain Dynamin_M PF01031.15 EAQ92531.1 - 1.2e-112 375.5 0.0 2.8e-112 374.2 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EAQ92531.1 - 1.2e-51 174.8 0.0 2.9e-51 173.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EAQ92531.1 - 8.7e-32 108.8 2.5 8.7e-32 108.8 1.7 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAQ92531.1 - 0.00098 19.0 0.0 0.0039 17.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ92531.1 - 0.015 15.7 0.0 0.061 13.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein WD40 PF00400.27 EAQ92532.1 - 1.4e-76 249.8 25.8 3.3e-14 52.1 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EAQ92532.1 - 9.8e-10 38.4 0.0 5.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAQ92532.1 - 1.7e-08 32.8 0.8 0.0018 16.1 0.0 2.1 2 0 0 2 2 2 2 IKI3 family Nup160 PF11715.3 EAQ92532.1 - 7.6e-08 30.9 4.1 0.015 13.4 0.0 4.5 2 2 3 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.7 EAQ92532.1 - 4.1e-06 26.3 7.8 3 7.6 0.0 5.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EAQ92532.1 - 0.00012 21.3 3.0 1.4 7.9 0.0 4.3 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EAQ92532.1 - 0.0018 16.6 0.0 0.17 10.1 0.0 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain DPPIV_N PF00930.16 EAQ92532.1 - 0.016 13.8 3.0 9.5 4.6 0.0 4.2 3 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3312 PF11768.3 EAQ92532.1 - 0.023 12.9 0.0 0.49 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF1513 PF07433.6 EAQ92532.1 - 0.026 13.4 0.2 2.4 7.0 0.0 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 EAQ92532.1 - 0.042 12.6 0.3 0.67 8.6 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like Pectate_lyase_3 PF12708.2 EAQ92534.1 - 6.6e-66 222.6 13.9 1.3e-51 175.8 2.5 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EAQ92534.1 - 1.6e-05 24.2 4.9 0.044 13.2 0.1 2.9 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.1 EAQ92534.1 - 0.00095 19.3 0.1 0.0037 17.3 0.0 2.0 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF2613 PF11021.3 EAQ92534.1 - 0.043 13.5 2.5 0.13 11.9 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CFEM PF05730.6 EAQ92535.1 - 1.4e-33 114.4 31.1 1.9e-13 49.9 4.2 5.3 5 0 0 5 5 5 3 CFEM domain LysM PF01476.15 EAQ92535.1 - 0.0099 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.14 EAQ92535.1 - 0.017 15.0 20.1 0.017 15.0 13.9 7.8 8 1 1 9 9 9 0 Chitin recognition protein Pex14_N PF04695.8 EAQ92535.1 - 1.5 8.8 7.3 3.1 7.8 5.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF566 PF04484.7 EAQ92535.1 - 3.5 7.0 7.6 5.2 6.4 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) p450 PF00067.17 EAQ92536.1 - 2.7e-66 223.9 0.0 1.2e-51 175.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Ribonuc_L-PSP PF01042.16 EAQ92539.1 - 3.1e-41 139.9 0.1 3.4e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.13 EAQ92540.1 - 8.4e-62 208.7 22.8 1.5e-60 204.5 11.7 2.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EAQ92540.1 - 1.7e-19 70.1 1.6 3.9e-18 65.6 0.5 2.2 1 1 1 2 2 2 2 MIR domain Fascin PF06268.8 EAQ92540.1 - 0.087 12.9 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Fascin domain zf-C2H2 PF00096.21 EAQ92541.1 - 0.014 15.7 2.6 0.014 15.7 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ92541.1 - 0.29 11.5 16.5 0.075 13.3 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Helicase_C PF00271.26 EAQ92543.1 - 2.1e-20 72.3 0.1 4.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ92543.1 - 4.1e-20 71.9 0.0 1.2e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EAQ92543.1 - 7.9e-20 71.4 0.0 1.7e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAQ92543.1 - 0.005 16.9 0.0 0.02 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain FXR1P_C PF12235.3 EAQ92543.1 - 0.026 14.6 7.7 0.1 12.6 5.4 2.0 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal AAA_10 PF12846.2 EAQ92543.1 - 0.04 13.3 0.3 12 5.2 0.0 3.4 2 2 0 3 3 3 0 AAA-like domain DUF2075 PF09848.4 EAQ92543.1 - 0.14 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) LRR_4 PF12799.2 EAQ92544.1 - 2.3e-06 27.0 0.0 1.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EAQ92544.1 - 0.00028 21.2 0.0 0.0005 20.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 EAQ92544.1 - 0.00032 20.2 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EAQ92544.1 - 0.014 15.0 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 EAQ92544.1 - 0.021 14.7 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 EAQ92544.1 - 0.026 14.6 0.2 0.39 11.1 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EAQ92544.1 - 0.088 12.9 0.1 0.63 10.2 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeat HLH PF00010.21 EAQ92546.1 - 2.1e-17 62.5 0.0 4.5e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MSC PF09402.5 EAQ92547.1 - 6.8e-109 363.6 0.0 8.7e-109 363.2 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EAQ92547.1 - 2.5e-17 62.1 0.1 8.7e-17 60.3 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain DUF3350 PF11830.3 EAQ92547.1 - 0.011 15.7 6.0 0.31 11.0 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) Dermcidin PF15291.1 EAQ92547.1 - 0.054 13.7 0.3 0.054 13.7 0.2 2.0 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide Thymopoietin PF08198.6 EAQ92547.1 - 0.065 12.7 0.1 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Thymopoietin protein SYCE1 PF15233.1 EAQ92547.1 - 0.086 12.7 1.0 0.18 11.7 0.7 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 HisG PF01634.13 EAQ92548.1 - 9.1e-49 165.1 0.2 1.8e-47 160.9 0.1 2.3 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EAQ92548.1 - 2.6e-26 91.3 0.3 5.3e-26 90.3 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain MFS_2 PF13347.1 EAQ92549.1 - 3.5e-11 42.1 0.7 3.5e-11 42.1 0.5 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 EAQ92549.1 - 0.07 12.9 2.6 0.19 11.5 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family DUF3040 PF11239.3 EAQ92549.1 - 0.58 10.2 2.8 4.8 7.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Sel1 PF08238.7 EAQ92550.1 - 1.1e-33 114.9 32.8 5e-05 23.8 0.1 7.7 8 0 0 8 8 8 7 Sel1 repeat Chitin_synth_2 PF03142.10 EAQ92552.1 - 1.4e-248 825.6 5.8 1.2e-245 815.9 4.0 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EAQ92552.1 - 1.1e-17 64.3 8.9 1.3e-16 60.9 6.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAQ92552.1 - 2.3e-14 53.7 0.0 3.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAQ92552.1 - 1e-05 24.9 0.0 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EAQ92552.1 - 0.021 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 WD40 PF00400.27 EAQ92553.1 - 3.7e-09 36.1 0.6 1.2e-07 31.2 0.3 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 EAQ92553.1 - 0.019 14.6 0.0 0.5 10.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) RRN3 PF05327.6 EAQ92553.1 - 3.7 5.5 4.4 5.8 4.8 3.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_17 PF00332.13 EAQ92554.1 - 0.057 12.4 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 RNB PF00773.14 EAQ92555.1 - 9.3e-68 228.8 0.0 1.3e-67 228.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain FliJ PF02050.11 EAQ92555.1 - 0.00057 19.9 0.6 0.0011 19.0 0.4 1.4 1 0 0 1 1 1 1 Flagellar FliJ protein Sec10 PF07393.6 EAQ92556.1 - 2.1e-234 779.9 4.6 2.4e-234 779.7 3.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Prenyltransf PF01255.14 EAQ92557.1 - 1.8e-07 30.5 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Met_10 PF02475.11 EAQ92558.1 - 5.9e-63 212.0 0.0 9.3e-63 211.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EAQ92558.1 - 0.075 13.6 0.0 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF1752 PF08550.5 EAQ92559.1 - 4.7e-09 35.6 4.2 9.5e-09 34.6 2.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Spt5_N PF11942.3 EAQ92559.1 - 0.13 12.8 8.7 4.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 EAQ92559.1 - 0.14 12.4 9.4 1.5 9.1 1.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 EAQ92559.1 - 0.35 11.0 3.3 0.47 10.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Proteasome PF00227.21 EAQ92560.1 - 2.5e-48 163.8 0.2 3e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 EAQ92560.1 - 0.042 13.7 0.4 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DUF554 PF04474.7 EAQ92560.1 - 0.089 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Peptidase_M22 PF00814.20 EAQ92561.1 - 1.9e-43 148.8 0.0 2.6e-42 145.1 0.0 2.2 1 1 0 1 1 1 1 Glycoprotease family Herpes_US9 PF06072.6 EAQ92561.1 - 0.0078 16.0 0.8 0.0078 16.0 0.5 2.7 3 0 0 3 3 3 1 Alphaherpesvirus tegument protein US9 FGGY_C PF02782.11 EAQ92561.1 - 0.047 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Glyco_transf_34 PF05637.7 EAQ92562.1 - 2.6e-44 151.5 0.1 1.8e-43 148.7 0.0 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_16 PF00722.16 EAQ92563.1 - 1.6e-07 30.7 0.0 3.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 EAQ92563.1 - 0.0082 15.6 0.2 0.033 13.7 0.1 2.1 1 0 0 1 1 1 1 Adenoviral fibre protein (repeat/shaft region) Ank_4 PF13637.1 EAQ92564.1 - 2e-34 117.3 1.7 8.6e-11 42.0 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ92564.1 - 7.5e-31 106.3 0.0 5.5e-17 61.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ92564.1 - 5e-25 86.0 0.1 6.5e-05 22.5 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EAQ92564.1 - 1.1e-16 60.5 0.5 6.5e-07 29.3 0.0 3.2 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92564.1 - 1.3e-15 55.9 0.0 0.016 15.3 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat NACHT PF05729.7 EAQ92564.1 - 3.9e-07 29.8 0.1 1.3e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ92564.1 - 0.00019 21.4 0.1 0.00069 19.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 EAQ92564.1 - 0.00081 18.7 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 EAQ92564.1 - 0.0013 18.8 0.0 0.0067 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 EAQ92564.1 - 0.0024 17.5 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EAQ92564.1 - 0.022 14.4 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_19 PF13245.1 EAQ92564.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EAQ92564.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EAQ92564.1 - 0.049 13.0 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EAQ92564.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EAQ92564.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EAQ92564.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAQ92564.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Abhydrolase_2 PF02230.11 EAQ92565.1 - 9.6e-24 84.0 0.3 1.2e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAQ92565.1 - 6.9e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family V_ATPase_I PF01496.14 EAQ92565.1 - 0.021 12.6 2.5 0.038 11.8 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EAQ92565.1 - 0.026 12.9 5.7 0.04 12.3 3.9 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S9 PF00326.16 EAQ92565.1 - 0.033 13.3 0.2 0.1 11.7 0.2 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EAQ92565.1 - 0.041 13.4 0.0 0.097 12.2 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold OS-D PF03392.8 EAQ92565.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF904 PF06005.7 EAQ92565.1 - 0.28 11.4 7.9 0.35 11.1 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 EAQ92565.1 - 0.76 9.5 12.7 9.2 6.0 7.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.4 EAQ92565.1 - 2 8.6 4.3 1.8 8.8 0.2 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3500 PF12006.3 EAQ92566.1 - 4.7e-91 304.9 0.0 5.6e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Med16 PF11635.3 EAQ92567.1 - 2.4e-60 204.4 0.0 4.5e-33 114.2 0.1 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 Ribosomal_60s PF00428.14 EAQ92567.1 - 1.4 9.3 6.4 0.13 12.6 1.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein BSP_II PF05432.6 EAQ92567.1 - 2.5 7.3 9.2 3.7 6.7 6.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SIR2 PF02146.12 EAQ92568.1 - 1.6e-27 96.3 0.0 6.3e-27 94.4 0.0 1.8 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.18 EAQ92569.1 - 3.5e-66 223.0 0.0 6e-66 222.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EAQ92569.1 - 3.9e-26 90.4 5.5 3e-15 55.6 0.2 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EAQ92569.1 - 5.7e-15 54.9 0.0 2e-14 53.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain POR PF01558.13 EAQ92569.1 - 0.048 13.5 0.3 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase ABC_tran PF00005.22 EAQ92570.1 - 3.3e-16 59.8 0.0 1.3e-06 28.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EAQ92570.1 - 5.2e-07 29.9 4.9 0.065 13.1 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_17 PF13207.1 EAQ92570.1 - 2.6e-06 28.2 0.2 0.055 14.2 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EAQ92570.1 - 6.6e-06 26.3 0.0 0.0078 16.4 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EAQ92570.1 - 1.6e-05 25.2 0.2 0.32 11.3 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAQ92570.1 - 4.2e-05 22.9 0.3 0.053 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EAQ92570.1 - 5.8e-05 23.2 0.0 0.019 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EAQ92570.1 - 7.4e-05 21.9 0.0 2.6 6.9 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 EAQ92570.1 - 0.0001 22.6 0.1 0.015 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 EAQ92570.1 - 0.00027 20.4 0.0 0.81 9.1 0.0 2.7 2 0 0 2 2 2 2 Virulence-associated protein E AAA_16 PF13191.1 EAQ92570.1 - 0.00029 20.8 0.1 0.81 9.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EAQ92570.1 - 0.0003 20.0 0.0 0.72 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EAQ92570.1 - 0.0003 20.5 1.1 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EAQ92570.1 - 0.00054 20.0 0.1 0.25 11.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 EAQ92570.1 - 0.00066 19.2 0.1 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EAQ92570.1 - 0.0011 18.4 2.4 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SMC_N PF02463.14 EAQ92570.1 - 0.0016 17.6 0.5 3.3 6.8 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EAQ92570.1 - 0.0022 17.9 0.3 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EAQ92570.1 - 0.0025 17.2 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase AAA_33 PF13671.1 EAQ92570.1 - 0.0026 17.6 0.5 0.15 11.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EAQ92570.1 - 0.0032 17.1 3.3 0.16 11.6 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.1 EAQ92570.1 - 0.0046 16.3 0.1 1.7 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAQ92570.1 - 0.0046 16.6 0.5 0.23 11.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 EAQ92570.1 - 0.0082 14.6 1.2 0.01 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAQ92570.1 - 0.012 14.5 0.0 0.63 8.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EAQ92570.1 - 0.016 13.9 0.0 0.17 10.4 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Miro PF08477.8 EAQ92570.1 - 0.018 15.5 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EAQ92570.1 - 0.04 13.5 0.1 0.72 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EAQ92570.1 - 0.06 12.8 3.5 0.08 12.4 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EAQ92570.1 - 0.062 13.1 0.4 16 5.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain MukB PF04310.7 EAQ92570.1 - 0.097 11.9 0.9 7.6 5.8 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal T2SE PF00437.15 EAQ92570.1 - 0.15 10.9 0.2 4.2 6.2 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EAQ92570.1 - 0.17 11.6 2.4 5.4 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EAQ92570.1 - 0.17 11.4 0.9 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FF PF01846.14 EAQ92571.1 - 2.2e-50 168.4 7.0 1.3e-12 47.4 0.0 7.1 6 1 0 6 6 6 6 FF domain WW PF00397.21 EAQ92571.1 - 4.7e-18 64.7 12.3 2.3e-10 40.1 2.8 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 EAQ92572.1 - 1e-58 199.0 0.0 1.8e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SLD3 PF08639.5 EAQ92573.1 - 2.1e-140 468.6 0.0 2.9e-140 468.2 0.0 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 Pkinase PF00069.20 EAQ92574.1 - 5.5e-22 78.1 0.0 1.4e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92574.1 - 1.5e-13 50.3 0.0 3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Homeobox PF00046.24 EAQ92575.1 - 2.6e-15 55.7 1.5 4.8e-15 54.9 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAQ92575.1 - 0.00017 21.2 0.1 0.00063 19.3 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain HAD_2 PF13419.1 EAQ92577.1 - 1.2e-11 45.1 0.0 1.7e-09 38.1 0.0 2.1 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAQ92577.1 - 1.8e-09 37.1 0.0 3.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EAQ92577.1 - 4.5e-07 30.5 0.0 0.00062 20.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 EAQ92577.1 - 0.13 12.2 0.5 0.22 11.5 0.0 1.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 GN3L_Grn1 PF08701.6 EAQ92578.1 - 1.4e-25 88.9 16.3 3e-25 87.9 11.3 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EAQ92578.1 - 2.6e-20 72.5 0.1 2e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAQ92578.1 - 8e-07 28.6 0.0 0.0079 15.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAQ92578.1 - 2.2e-06 27.6 2.2 0.15 11.8 0.1 3.7 2 2 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EAQ92578.1 - 0.00046 19.4 0.1 0.00076 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAQ92578.1 - 0.0033 16.7 0.1 0.036 13.3 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EAQ92578.1 - 0.017 15.6 0.1 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EAQ92578.1 - 0.073 13.0 5.5 0.19 11.6 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EAQ92578.1 - 0.1 11.3 1.9 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 ArgK protein DUF1675 PF07897.6 EAQ92578.1 - 0.26 11.1 5.0 0.56 10.0 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AAA_18 PF13238.1 EAQ92578.1 - 0.73 10.1 0.0 0.73 10.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EAQ92578.1 - 0.87 10.4 0.0 0.87 10.4 0.0 2.7 2 1 0 2 2 1 0 AAA domain Nop14 PF04147.7 EAQ92578.1 - 3.9 5.2 28.4 6.1 4.6 19.7 1.2 1 0 0 1 1 1 0 Nop14-like family RNB PF00773.14 EAQ92579.1 - 1.3e-92 310.5 0.0 2e-92 309.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EAQ92579.1 - 1.2e-09 38.3 1.5 2.7e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 PIN domain OB_RNB PF08206.6 EAQ92579.1 - 0.043 13.3 0.1 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain CRC_subunit PF08624.5 EAQ92581.1 - 7.3e-54 181.4 0.0 1.1e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.18 EAQ92582.1 - 3e-06 27.2 0.1 4.6e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAQ92582.1 - 0.0012 18.9 0.1 0.0018 18.3 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EAQ92582.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HpaP PF09483.5 EAQ92582.1 - 0.12 12.3 4.4 0.19 11.6 3.0 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF3188 PF11384.3 EAQ92583.1 - 0.12 11.9 0.8 0.28 10.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Nucleos_tra2_N PF01773.15 EAQ92583.1 - 0.22 11.8 0.6 23 5.4 0.0 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus Gram_pos_anchor PF00746.16 EAQ92583.1 - 0.39 10.5 3.2 0.6 9.9 0.6 2.2 2 0 0 2 2 2 0 Gram positive anchor Aldedh PF00171.17 EAQ92585.1 - 2e-107 359.3 0.0 2.5e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.21 EAQ92586.1 - 6.5e-13 48.1 0.3 1.9e-12 46.7 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TEBP_beta PF07404.6 EAQ92586.1 - 1.5 7.9 7.2 2.4 7.1 5.0 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) PhoD PF09423.5 EAQ92587.1 - 9.6e-08 31.0 0.1 2.1e-06 26.5 0.1 2.3 2 1 0 2 2 2 2 PhoD-like phosphatase Rhomboid PF01694.17 EAQ92588.1 - 4.2e-22 78.7 10.7 4.2e-22 78.7 6.7 1.6 1 1 0 1 1 1 1 Rhomboid family DUF3530 PF12048.3 EAQ92589.1 - 0.052 12.5 1.0 0.063 12.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Herpes_UL25 PF01499.11 EAQ92591.1 - 0.27 9.5 2.3 0.45 8.7 1.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family IU_nuc_hydro PF01156.14 EAQ92592.1 - 1.7e-55 188.4 0.2 7.9e-45 153.4 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase DUF2188 PF09954.4 EAQ92592.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) HpcH_HpaI PF03328.9 EAQ92593.1 - 1.1e-20 73.4 0.0 5.9e-20 71.1 0.0 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EAQ92593.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain CHORD PF04968.7 EAQ92594.1 - 6.2e-47 157.7 18.7 7.8e-26 90.1 2.9 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 EAQ92594.1 - 2.3e-14 53.6 0.0 3.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 CS domain BCD PF15461.1 EAQ92595.1 - 0.02 14.3 2.3 0.028 13.8 1.6 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase WH2 PF02205.15 EAQ92597.1 - 1.3e-11 43.6 2.6 3.8e-11 42.2 0.2 2.6 2 0 0 2 2 2 1 WH2 motif RRM_1 PF00076.17 EAQ92600.1 - 5.1e-41 138.1 0.0 1.8e-19 69.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ92600.1 - 4.5e-31 106.6 0.0 1.4e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ92600.1 - 1e-18 66.9 0.0 5.6e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAQ92600.1 - 0.041 13.6 0.8 1 9.1 0.0 3.4 3 2 0 3 3 3 0 Limkain b1 NDUFB10 PF10249.4 EAQ92601.1 - 0.0013 18.9 0.3 0.0018 18.4 0.2 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EAQ92601.1 - 0.06 13.7 0.0 0.097 13.1 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.5 EAQ92602.1 - 1.5e-29 101.4 0.6 3.6e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 TAFII55_N PF04658.8 EAQ92603.1 - 2.7e-49 166.7 0.0 4.5e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Prothymosin PF03247.9 EAQ92603.1 - 0.001 19.1 11.9 0.001 19.1 8.2 3.3 3 0 0 3 3 3 1 Prothymosin/parathymosin family DUF3245 PF11595.3 EAQ92603.1 - 1.4 9.1 19.1 5.1 7.3 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.14 EAQ92603.1 - 2.2 8.7 33.5 0.97 9.8 10.9 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4094 PF13334.1 EAQ92603.1 - 4.2 7.8 5.5 0.93 9.9 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Bromo_TP PF07524.8 EAQ92604.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated DUF3186 PF11382.3 EAQ92604.1 - 0.078 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DUF2281 PF10047.4 EAQ92604.1 - 0.12 12.6 0.1 0.49 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) Glyco_hydro_15 PF00723.16 EAQ92605.1 - 7.6e-53 179.6 0.0 1.3e-50 172.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 EAQ92606.1 - 1.2e-09 38.0 0.1 1.2e-09 38.0 0.1 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EAQ92606.1 - 0.0061 15.5 10.2 0.02 13.8 6.3 2.0 1 1 1 2 2 2 1 UAA transporter family CD99L2 PF12301.3 EAQ92606.1 - 0.067 12.8 3.9 0.11 12.1 2.2 1.6 1 1 0 1 1 1 0 CD99 antigen like protein 2 EamA PF00892.15 EAQ92606.1 - 1 9.4 20.2 0.027 14.5 7.1 3.1 2 1 1 3 3 3 0 EamA-like transporter family RRM_1 PF00076.17 EAQ92607.1 - 3.1e-17 61.9 0.1 4.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ92607.1 - 1.3e-12 47.4 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ92607.1 - 4.3e-05 23.2 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EAQ92607.1 - 0.071 12.6 0.2 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 EAQ92608.1 - 6.4e-135 448.9 0.0 8e-135 448.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EAQ92608.1 - 2.6e-44 150.9 0.0 4.3e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EAQ92608.1 - 0.096 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SWI-SNF_Ssr4 PF08549.5 EAQ92609.1 - 2.8e-216 719.9 17.5 1.1e-120 404.0 6.3 2.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Ribosomal_S17 PF00366.15 EAQ92610.1 - 2e-16 59.7 0.5 3.3e-16 59.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EAQ92611.1 - 3.6e-142 475.4 41.3 5.5e-115 385.4 22.9 2.0 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EAQ92612.1 - 3.9e-103 344.5 9.4 3.9e-103 344.5 6.5 1.3 1 1 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.1 EAQ92612.1 - 7.5e-90 302.2 20.3 7.5e-90 302.2 14.1 1.5 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.1 EAQ92612.1 - 7.8e-12 44.6 0.1 2.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Spc7_C2 IncA PF04156.9 EAQ92612.1 - 0.00077 19.1 11.3 0.00077 19.1 7.8 1.8 2 0 0 2 2 2 1 IncA protein Laminin_II PF06009.7 EAQ92612.1 - 0.066 12.9 3.0 0.14 11.8 2.0 1.6 1 0 0 1 1 1 0 Laminin Domain II KxDL PF10241.4 EAQ92612.1 - 0.075 12.9 1.2 0.26 11.2 0.5 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein V_ATPase_I PF01496.14 EAQ92612.1 - 0.7 7.6 3.7 1 7.1 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EAQ92614.1 - 7.3e-67 225.4 4.0 1.8e-63 214.3 2.8 2.1 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Laminin_I PF06008.9 EAQ92614.1 - 0.034 13.4 5.8 0.11 11.8 4.4 1.5 1 1 0 1 1 1 0 Laminin Domain I Spectrin PF00435.16 EAQ92614.1 - 0.18 12.1 2.9 0.31 11.3 2.0 1.4 1 0 0 1 1 1 0 Spectrin repeat APG6 PF04111.7 EAQ92614.1 - 2.5 7.0 5.0 3.5 6.5 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3807 PF12720.2 EAQ92616.1 - 2.4e-49 167.7 5.8 2.8e-49 167.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) NAD_binding_1 PF00175.16 EAQ92617.1 - 5.8e-31 107.2 0.0 1.4e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EAQ92617.1 - 3.9e-20 71.8 0.0 7.1e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EAQ92617.1 - 3.4e-09 36.7 0.0 0.00021 21.2 0.0 2.6 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EAQ92617.1 - 0.00073 19.4 0.0 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain SH3_9 PF14604.1 EAQ92618.1 - 5.8e-09 35.3 0.2 1.3e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ92618.1 - 1.1e-08 34.3 0.0 1.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAQ92618.1 - 7.9e-06 25.2 0.0 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.8 EAQ92620.1 - 2e-83 278.5 0.0 2.3e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 EAQ92621.1 - 2.2e-22 78.0 3.8 1.5e-13 49.8 0.9 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT AAA_13 PF13166.1 EAQ92621.1 - 0.012 14.1 17.7 0.021 13.2 12.3 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EAQ92621.1 - 0.025 12.4 12.4 0.05 11.4 8.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cast PF10174.4 EAQ92621.1 - 0.035 12.1 32.7 0.0036 15.4 10.1 2.2 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone APG6 PF04111.7 EAQ92621.1 - 0.043 12.8 34.4 0.012 14.6 13.4 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3138 PF11336.3 EAQ92621.1 - 0.15 10.2 0.4 0.26 9.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4407 PF14362.1 EAQ92621.1 - 1.6 7.6 28.5 0.16 10.8 12.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Filament PF00038.16 EAQ92621.1 - 2.1 7.7 31.2 5 6.5 8.5 2.4 1 1 0 2 2 2 0 Intermediate filament protein FUSC PF04632.7 EAQ92621.1 - 2.9 6.1 12.2 5.8 5.2 8.5 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hormone_1 PF00103.15 EAQ92621.1 - 3 7.1 7.7 3.5 6.9 3.6 2.4 1 1 1 2 2 2 0 Somatotropin hormone family Prefoldin PF02996.12 EAQ92621.1 - 3.2 7.4 25.0 0.99 9.0 0.4 4.6 3 1 1 4 4 4 0 Prefoldin subunit DUF3584 PF12128.3 EAQ92621.1 - 5.9 4.0 28.8 10 3.3 20.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MARVEL PF01284.18 EAQ92622.1 - 4.9e-09 36.1 6.4 8.1e-09 35.4 4.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain TFR_dimer PF04253.10 EAQ92623.1 - 5.4e-22 77.7 0.0 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EAQ92623.1 - 3.6e-14 52.8 0.0 1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAQ92623.1 - 1.5e-06 27.7 0.5 4.3e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 PA domain BLOC1_2 PF10046.4 EAQ92623.1 - 0.013 15.6 0.5 0.96 9.6 0.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.13 EAQ92623.1 - 0.051 13.0 0.9 0.096 12.1 0.6 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain phiKZ_IP PF12699.2 EAQ92623.1 - 0.35 9.7 0.4 0.63 8.9 0.3 1.3 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Cytochrom_C_2 PF01322.15 EAQ92623.1 - 0.81 10.2 4.5 0.49 10.9 1.6 1.7 2 0 0 2 2 2 0 Cytochrome C' MFS_1 PF07690.11 EAQ92624.1 - 1.2e-25 90.0 36.2 9.1e-17 60.7 8.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ92624.1 - 2.9e-06 26.1 7.3 2.9e-06 26.1 5.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Peptidase_A8 PF01252.13 EAQ92624.1 - 2.6 7.6 6.1 0.35 10.4 0.3 2.5 2 1 0 2 2 2 0 Signal peptidase (SPase) II RasGAP_C PF03836.10 EAQ92625.1 - 3.7e-44 149.8 1.2 3.7e-44 149.8 0.8 2.1 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EAQ92625.1 - 2.7e-26 92.4 0.0 1.5e-12 47.5 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EAQ92625.1 - 1.9e-20 70.4 34.6 0.022 14.3 0.6 13.7 14 0 0 14 14 14 9 IQ calmodulin-binding motif CH PF00307.26 EAQ92625.1 - 1e-09 38.3 0.0 2.8e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 EAQ92626.1 - 6e-132 439.8 4.3 7.3e-132 439.5 3.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EAQ92626.1 - 8.2e-18 63.9 0.1 7.2e-09 35.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EAQ92626.1 - 2.5e-09 36.4 1.9 4.5e-08 32.3 0.7 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EAQ92626.1 - 1.7e-07 30.7 9.2 0.011 14.8 6.3 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EAQ92626.1 - 0.00014 21.2 2.5 0.0079 15.4 0.3 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein AlaDh_PNT_N PF05222.10 EAQ92627.1 - 5e-30 104.2 0.0 7.9e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EAQ92627.1 - 2.5e-15 56.4 0.1 3.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 EAQ92628.1 - 4.5e-10 38.8 2.0 8.3e-10 37.9 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ92628.1 - 0.0023 17.8 5.4 0.0047 16.8 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.3 EAQ92629.1 - 0.00011 21.8 0.1 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) Pkinase PF00069.20 EAQ92630.1 - 1.1e-58 198.3 0.0 1.3e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92630.1 - 1.2e-16 60.5 0.0 2.2e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAQ92630.1 - 4.8e-05 23.2 0.1 0.18 11.4 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAQ92630.1 - 0.1 11.9 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL V-SNARE PF05008.10 EAQ92631.1 - 2.6e-21 75.5 2.3 2.6e-21 75.5 1.6 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EAQ92631.1 - 1.6e-13 50.5 2.5 1.6e-13 50.5 1.7 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EAQ92631.1 - 0.015 14.9 2.5 0.018 14.7 0.5 2.1 2 1 0 2 2 2 0 Sec20 Use1 PF09753.4 EAQ92631.1 - 0.018 14.4 5.7 0.14 11.6 3.9 2.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Myosin_tail_1 PF01576.14 EAQ92631.1 - 0.063 11.0 8.5 0.12 10.1 0.6 2.1 2 0 0 2 2 2 0 Myosin tail Unstab_antitox PF09720.5 EAQ92631.1 - 0.094 12.4 0.0 0.26 11.0 0.0 1.8 1 1 0 1 1 1 0 Putative addiction module component YqjK PF13997.1 EAQ92631.1 - 0.11 12.6 4.7 0.7 10.1 0.2 3.1 3 0 0 3 3 3 0 YqjK-like protein Spc7 PF08317.6 EAQ92631.1 - 0.17 10.5 5.8 0.29 9.7 2.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Metal_resist PF13801.1 EAQ92631.1 - 2.5 8.0 7.9 0.35 10.8 1.3 2.6 1 1 2 3 3 3 0 Heavy-metal resistance APG6 PF04111.7 EAQ92632.1 - 2.3e-111 371.8 0.0 3.1e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Atg14 PF10186.4 EAQ92632.1 - 0.0088 15.0 5.4 0.046 12.6 3.7 1.9 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 BBS2_C PF14782.1 EAQ92632.1 - 0.03 12.9 1.3 0.045 12.3 0.9 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal IncA PF04156.9 EAQ92632.1 - 0.04 13.5 10.4 0.085 12.4 7.2 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EAQ92632.1 - 0.22 9.3 3.9 0.29 8.9 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 EAQ92632.1 - 0.33 10.1 12.1 0.17 11.1 5.5 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF2968 PF11180.3 EAQ92632.1 - 0.36 10.1 10.9 0.79 9.0 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF342 PF03961.8 EAQ92632.1 - 0.49 8.7 2.3 0.72 8.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FUSC PF04632.7 EAQ92632.1 - 0.57 8.5 2.8 0.73 8.2 1.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBPIP PF07106.8 EAQ92632.1 - 0.62 9.5 3.7 1.1 8.7 2.6 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EAQ92632.1 - 0.65 10.3 3.6 0.26 11.6 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EAQ92632.1 - 0.9 9.1 6.5 1.7 8.2 4.5 1.5 1 0 0 1 1 1 0 Mnd1 family GAS PF13851.1 EAQ92632.1 - 2.3 7.3 9.2 9.7 5.3 6.4 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EAQ92632.1 - 2.4 7.9 15.3 1.9 8.3 8.4 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.1 EAQ92632.1 - 6.6 6.7 11.9 3.9 7.4 5.5 2.4 1 1 1 2 2 2 0 Up-regulated During Septation DUF4337 PF14235.1 EAQ92632.1 - 7.8 6.3 8.1 16 5.2 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Glyco_hydro_45 PF02015.11 EAQ92633.1 - 3.4e-91 304.7 20.2 3.9e-91 304.5 14.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Het-C PF07217.6 EAQ92634.1 - 3.2e-240 798.4 1.9 1.4e-120 403.3 0.6 2.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C HMG_box PF00505.14 EAQ92636.1 - 2.1e-06 27.9 0.0 4.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ92636.1 - 0.00035 20.8 0.0 0.0011 19.2 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain Urease_alpha PF00449.15 EAQ92637.1 - 3.9e-54 181.9 4.7 5.1e-54 181.5 1.6 2.4 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EAQ92637.1 - 6.6e-38 128.5 0.0 1.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EAQ92637.1 - 2.7e-26 91.4 0.0 6.4e-26 90.2 0.0 1.7 1 1 0 1 1 1 1 Urease, gamma subunit Amidohydro_1 PF01979.15 EAQ92637.1 - 2.1e-20 73.6 0.3 3.9e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF605 PF04652.11 EAQ92637.1 - 3.9 6.7 8.0 5.6 6.2 5.6 1.1 1 0 0 1 1 1 0 Vta1 like tRNA-synt_2b PF00587.20 EAQ92639.1 - 3.4e-50 170.0 0.0 5.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Maf PF02545.9 EAQ92639.1 - 1.7e-35 121.9 0.1 1.2e-30 106.1 0.0 2.4 2 0 0 2 2 2 2 Maf-like protein HGTP_anticodon PF03129.15 EAQ92639.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Glyco_hydro_47 PF01532.15 EAQ92640.1 - 1.6e-163 544.6 0.0 1.9e-163 544.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp11 PF03998.8 EAQ92641.1 - 1.8e-48 165.4 10.2 2.2e-48 165.2 7.1 1.1 1 0 0 1 1 1 1 Utp11 protein Bd3614_N PF14442.1 EAQ92641.1 - 0.093 12.7 3.5 0.15 12.0 2.4 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase N-terminal DUF4337 PF14235.1 EAQ92641.1 - 1.4 8.7 4.1 2.3 8.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DAO PF01266.19 EAQ92643.1 - 5.7e-23 81.3 4.1 8.7e-23 80.7 2.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ92643.1 - 2.4e-05 24.6 1.1 6.1e-05 23.3 0.8 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAQ92643.1 - 0.00029 19.9 0.2 0.00047 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAQ92643.1 - 0.00042 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ92643.1 - 0.0011 18.8 1.7 0.0035 17.3 0.9 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EAQ92643.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EAQ92643.1 - 0.0013 17.6 0.3 0.002 17.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EAQ92643.1 - 0.0017 17.9 0.1 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EAQ92643.1 - 0.003 17.7 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EAQ92643.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EAQ92643.1 - 0.024 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EAQ92643.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EAQ92643.1 - 0.12 12.1 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EAQ92643.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EAQ92643.1 - 0.34 9.9 0.1 0.34 9.9 0.0 2.2 3 0 0 3 3 2 0 Thi4 family fn3 PF00041.16 EAQ92644.1 - 3.4e-07 30.2 0.1 9.7e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain LNS2 PF08235.8 EAQ92645.1 - 3.1e-71 238.0 0.0 4.9e-71 237.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EAQ92645.1 - 1.4e-39 134.2 0.0 5e-39 132.3 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EAQ92645.1 - 0.00047 19.5 0.0 0.029 13.7 0.0 2.6 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) TFIID-31kDa PF02291.10 EAQ92646.1 - 5.6e-12 45.5 0.0 8.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Trypan_PARP PF05887.6 EAQ92646.1 - 0.024 14.4 13.9 0.03 14.1 9.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF605 PF04652.11 EAQ92646.1 - 0.57 9.5 26.3 0.59 9.4 18.2 1.0 1 0 0 1 1 1 0 Vta1 like Gag_spuma PF03276.9 EAQ92646.1 - 0.75 8.0 15.4 0.81 7.9 10.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 EAQ92646.1 - 2.5 7.9 14.5 2.9 7.7 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1421 PF07223.6 EAQ92646.1 - 3.8 7.1 41.9 4.8 6.8 29.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Ndc1_Nup PF09531.5 EAQ92646.1 - 3.9 5.7 7.1 4.2 5.6 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc7_N PF15402.1 EAQ92646.1 - 4 5.3 14.4 4.3 5.2 10.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4106 PF13388.1 EAQ92646.1 - 9.4 5.0 20.0 11 4.8 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Histidinol_dh PF00815.15 EAQ92647.1 - 6.4e-143 476.3 9.9 1.5e-109 366.3 2.8 2.5 1 1 1 2 2 2 2 Histidinol dehydrogenase PRA-CH PF01502.13 EAQ92647.1 - 7.9e-26 89.4 0.1 1.7e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EAQ92647.1 - 4.8e-09 36.3 0.1 1.6e-08 34.7 0.1 2.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase PLA2_B PF01735.13 EAQ92648.1 - 2.7e-175 583.2 0.0 3.4e-175 582.9 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Raptor_N PF14538.1 EAQ92649.1 - 0.038 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF3176 PF11374.3 EAQ92650.1 - 3.3e-26 91.3 2.2 5.7e-26 90.5 0.0 2.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3176) Cation_efflux PF01545.16 EAQ92651.1 - 9.7e-77 257.8 1.1 2.2e-76 256.6 0.7 1.5 1 1 0 1 1 1 1 Cation efflux family U79_P34 PF03064.11 EAQ92651.1 - 0.48 9.9 5.1 1.1 8.7 2.7 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 GST_N_3 PF13417.1 EAQ92652.1 - 8.7e-13 48.3 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAQ92652.1 - 1.7e-12 47.2 0.0 3.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAQ92652.1 - 5.2e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAQ92652.1 - 1.9e-09 37.4 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAQ92652.1 - 3.3e-05 23.6 0.1 5.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAQ92652.1 - 0.0028 18.1 0.0 0.0044 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EAQ92653.1 - 1.4e-07 31.1 0.1 3.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ92653.1 - 0.0011 18.5 0.0 0.0055 16.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.23 EAQ92653.1 - 0.012 15.1 0.0 0.28 10.8 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ92653.1 - 0.033 14.1 0.0 2.8 8.0 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat MDMPI_N PF11716.3 EAQ92653.1 - 4.9 7.5 13.1 1.4 9.3 0.7 3.1 4 0 0 4 4 4 0 Mycothiol maleylpyruvate isomerase N-terminal domain MBOAT PF03062.14 EAQ92654.1 - 2.1e-43 148.7 17.9 2.1e-43 148.7 12.4 2.2 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Far-17a_AIG1 PF04750.9 EAQ92655.1 - 9.2e-06 24.9 14.3 1.5e-05 24.2 9.9 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Cation_efflux PF01545.16 EAQ92655.1 - 1.4 7.9 8.5 54 2.7 5.7 2.4 1 1 0 1 1 1 0 Cation efflux family Prefoldin_3 PF13758.1 EAQ92657.1 - 4.2e-33 113.0 0.3 1.4e-32 111.3 0.2 2.0 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EAQ92657.1 - 9.4e-20 71.3 11.7 1.2e-14 55.0 0.0 6.0 6 1 0 6 6 6 2 Domain of unknown function (DUF3835) MIS13 PF08202.6 EAQ92657.1 - 0.0004 19.5 1.5 0.0004 19.5 1.1 1.9 2 0 0 2 2 2 1 Mis12-Mtw1 protein family CS PF04969.11 EAQ92658.1 - 2.7e-16 59.8 0.0 1.1e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 CS domain MAT1 PF06391.8 EAQ92659.1 - 1.8e-28 99.5 7.0 2.3e-28 99.1 4.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EAQ92659.1 - 0.0002 20.9 5.4 0.00046 19.7 3.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ92659.1 - 0.00079 19.0 6.4 0.0012 18.4 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ92659.1 - 0.0045 16.6 9.6 0.038 13.7 7.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAQ92659.1 - 0.0081 16.1 8.7 0.03 14.3 6.2 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF572 PF04502.8 EAQ92659.1 - 0.0095 15.1 0.5 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_2 PF13639.1 EAQ92659.1 - 0.02 14.7 7.1 0.077 12.8 5.1 1.8 1 1 1 2 2 2 0 Ring finger domain MRP-S26 PF14943.1 EAQ92659.1 - 0.1 12.1 13.7 0.16 11.5 9.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 eIF-3_zeta PF05091.7 EAQ92659.1 - 0.27 9.7 4.4 0.37 9.3 3.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-RING_UBOX PF13445.1 EAQ92659.1 - 0.4 10.4 3.8 0.88 9.3 2.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAQ92659.1 - 0.47 10.3 6.0 1 9.3 4.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAQ92659.1 - 1 9.0 10.1 13 5.4 7.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF2072 PF09845.4 EAQ92659.1 - 4.5 7.2 6.4 4.4 7.2 2.1 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) ANTH PF07651.11 EAQ92660.1 - 2.1e-70 236.6 0.6 2.6e-70 236.3 0.4 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EAQ92660.1 - 8e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.15 EAQ92661.1 - 3e-51 174.1 0.0 1e-43 149.4 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) p450 PF00067.17 EAQ92663.1 - 3.8e-73 246.5 0.0 4.8e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIS_M PF07500.9 EAQ92664.1 - 1.1e-25 89.9 1.6 1.2e-24 86.5 0.0 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EAQ92664.1 - 1.8e-18 65.8 7.6 3.6e-18 64.9 5.3 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EAQ92664.1 - 1.5e-15 56.4 0.8 3.6e-15 55.2 0.2 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LEDGF PF11467.3 EAQ92664.1 - 0.045 13.4 0.8 0.085 12.5 0.6 1.4 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) PALP PF00291.20 EAQ92665.1 - 3.6e-55 187.3 1.5 4.3e-55 187.0 1.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 EAQ92666.1 - 5.7e-30 104.5 0.0 9.8e-27 93.9 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EAQ92666.1 - 0.00073 18.5 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.14 EAQ92667.1 - 1.1e-158 529.0 0.4 6e-158 526.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EAQ92667.1 - 6.1e-17 61.2 0.2 1.6e-16 59.8 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GKAP PF03359.8 EAQ92668.1 - 1.8 8.1 6.3 3.9 6.9 0.2 2.2 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein RCR PF12273.3 EAQ92669.1 - 3.1e-05 24.5 13.5 0.00022 21.7 9.4 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SpoIIE PF07228.7 EAQ92670.1 - 3.1e-11 43.3 0.1 3.1e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EAQ92670.1 - 4.4e-11 42.6 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EAQ92670.1 - 1.8e-09 37.3 0.1 2.8e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C GPI-anchored PF10342.4 EAQ92671.1 - 9e-18 64.5 1.2 9e-18 64.5 0.8 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2141 PF09912.4 EAQ92671.1 - 0.035 13.7 0.0 2.1 8.0 0.0 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) Herpes_TAF50 PF03326.8 EAQ92671.1 - 0.21 10.5 12.5 0.24 10.3 8.6 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CytochromB561_N PF09786.4 EAQ92671.1 - 0.75 8.1 7.5 0.82 8.0 5.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pyr_redox_3 PF13738.1 EAQ92674.1 - 1.4e-22 80.7 0.0 5.8e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ92674.1 - 3.5e-10 39.7 0.1 1.3e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EAQ92674.1 - 4.8e-09 34.9 0.0 4.1e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EAQ92674.1 - 1e-06 27.9 0.0 0.00089 18.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EAQ92674.1 - 1.5e-05 24.8 0.2 0.0057 16.4 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EAQ92674.1 - 0.00012 22.0 0.0 0.068 13.0 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Patatin PF01734.17 EAQ92675.1 - 4.9e-24 85.3 0.0 1.1e-23 84.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.1 EAQ92675.1 - 7.4e-12 45.0 3.7 6.8e-05 22.7 0.2 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.17 EAQ92675.1 - 3.5e-08 32.6 0.0 7.3e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EAQ92675.1 - 0.00021 21.3 0.1 0.00079 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 EAQ92675.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_10 PF13374.1 EAQ92675.1 - 0.15 12.0 8.7 0.25 11.3 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ92676.1 - 3.5e-16 58.9 7.5 1.1e-05 25.2 0.1 5.2 3 2 1 4 4 4 4 Tetratricopeptide repeat Patatin PF01734.17 EAQ92676.1 - 1.8e-14 54.1 0.0 5.2e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EAQ92676.1 - 9.3e-13 47.6 0.0 6.9e-09 34.9 0.0 2.3 1 1 0 2 2 2 2 NB-ARC domain TPR_11 PF13414.1 EAQ92676.1 - 2.5e-07 30.2 5.0 0.026 14.1 0.1 4.8 4 1 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 EAQ92676.1 - 7.7e-06 26.0 11.3 6.3 7.7 0.0 6.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ92676.1 - 1.5e-05 24.4 17.7 0.52 10.3 0.1 6.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ92676.1 - 0.00012 21.4 9.2 0.76 9.4 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ92676.1 - 0.006 17.2 16.4 0.08 13.6 1.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 EAQ92676.1 - 0.0064 16.4 0.0 0.023 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.1 EAQ92676.1 - 0.0066 16.7 3.4 1.7 9.0 0.0 4.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ92676.1 - 0.11 12.5 17.5 0.82 9.6 0.2 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ92676.1 - 1.9 9.1 9.3 2.1 8.9 0.1 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ92676.1 - 9.5 6.2 14.5 3.7 7.5 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat HA2 PF04408.18 EAQ92677.1 - 5.4e-17 61.6 0.0 2.3e-16 59.6 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAQ92677.1 - 2.6e-16 59.4 0.0 8.1e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAQ92677.1 - 7.3e-14 51.3 0.0 2.8e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAQ92677.1 - 1.1e-05 25.0 0.0 4.7e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAQ92677.1 - 0.00013 22.1 0.0 0.00044 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAQ92677.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EAQ92677.1 - 0.059 12.5 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ92677.1 - 0.061 13.3 0.0 0.061 13.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 EAQ92677.1 - 0.079 13.2 0.0 0.079 13.2 0.0 2.8 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 EAQ92678.1 - 4.3e-10 39.3 0.0 1e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EAQ92678.1 - 0.022 14.2 0.5 0.055 13.0 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EAQ92678.1 - 0.19 11.2 1.1 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Rab5ip PF07019.7 EAQ92679.1 - 8e-27 93.2 0.7 1e-26 92.8 0.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.2 EAQ92680.1 - 1.3e-64 217.7 0.0 2.1e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes TPR_MLP1_2 PF07926.7 EAQ92680.1 - 1.2 8.8 5.2 0.24 11.1 0.7 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PCNA_N PF00705.13 EAQ92681.1 - 2.2e-56 188.8 4.9 8.2e-56 186.9 2.5 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EAQ92681.1 - 2.4e-51 172.9 0.2 7.8e-51 171.3 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EAQ92681.1 - 9.9e-10 37.9 0.1 1.2e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EAQ92681.1 - 7.1e-05 21.8 0.2 0.0063 15.4 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein FliW PF02623.10 EAQ92681.1 - 0.13 11.8 0.1 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 FliW protein Phos_pyr_kin PF08543.7 EAQ92682.1 - 0.00013 21.2 0.0 0.00055 19.2 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EAQ92682.1 - 0.0047 16.1 0.8 0.017 14.3 0.1 2.3 2 1 1 3 3 3 1 pfkB family carbohydrate kinase DUF1134 PF06577.7 EAQ92682.1 - 0.054 12.9 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Latarcin PF10279.4 EAQ92682.1 - 0.082 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Latarcin precursor dUTPase PF00692.14 EAQ92683.1 - 3.2e-41 139.7 0.0 4e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase CENP-K PF11802.3 EAQ92684.1 - 2.3e-13 49.9 1.4 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Centromere-associated protein K AAA_13 PF13166.1 EAQ92684.1 - 0.1 11.0 6.6 0.0082 14.6 1.4 1.4 2 0 0 2 2 2 0 AAA domain COG2 PF06148.6 EAQ92684.1 - 0.29 10.9 4.5 2.5 7.9 1.9 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EAQ92684.1 - 0.65 8.6 11.8 0.74 8.4 5.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.1 EAQ92684.1 - 4.3 7.3 22.4 1.7 8.6 9.0 2.9 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit KH_1 PF00013.24 EAQ92685.1 - 1.3e-40 136.8 7.5 1.4e-16 59.9 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EAQ92685.1 - 4.2e-31 106.0 13.4 2.6e-11 42.8 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EAQ92685.1 - 9.2e-13 47.5 5.7 0.0029 17.1 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EAQ92685.1 - 0.00027 20.5 2.9 0.95 9.1 0.1 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EAQ92685.1 - 0.0025 17.5 7.2 0.79 9.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain RVT_1 PF00078.22 EAQ92686.1 - 1.5e-16 60.4 0.0 2.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C12 PF01088.16 EAQ92687.1 - 7.4e-34 116.7 0.0 2.6e-31 108.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EAQ92687.1 - 0.0058 17.2 0.1 0.0094 16.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain DUF892 PF05974.7 EAQ92688.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Baculo_PEP_C PF04513.7 EAQ92688.1 - 0.12 12.2 2.1 0.18 11.6 0.1 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1765 PF08578.5 EAQ92689.1 - 2.6e-52 176.1 0.7 4.2e-52 175.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Cys_Met_Meta_PP PF01053.15 EAQ92690.1 - 2.2e-138 460.7 0.4 2.5e-138 460.5 0.3 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EAQ92690.1 - 1.2e-07 31.1 0.3 2.2e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EAQ92690.1 - 1.9e-07 30.1 1.2 3.5e-07 29.3 0.3 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EAQ92690.1 - 4e-07 29.3 0.2 6.2e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EAQ92690.1 - 0.00011 21.4 0.6 0.00023 20.4 0.4 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EAQ92690.1 - 0.0029 16.3 0.2 0.0029 16.3 0.1 1.6 2 0 0 2 2 2 1 Glycine cleavage system P-protein Fungal_trans_2 PF11951.3 EAQ92691.1 - 0.0001 21.0 0.3 0.00022 19.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ92691.1 - 0.0041 17.0 1.6 0.0077 16.1 1.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4554 PF15091.1 EAQ92691.1 - 0.03 13.0 0.1 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) GlcNAc_2-epim PF07221.6 EAQ92691.1 - 0.13 11.2 4.6 0.5 9.3 0.2 2.5 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Brix PF04427.13 EAQ92692.1 - 3.9e-37 127.7 0.0 5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain zf-MYND PF01753.13 EAQ92693.1 - 1.8e-08 34.1 10.5 3.5e-08 33.1 7.3 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EAQ92693.1 - 0.012 15.2 11.9 0.022 14.3 8.2 1.5 1 0 0 1 1 1 0 HIT zinc finger Ecl1 PF12855.2 EAQ92693.1 - 0.75 9.1 6.7 2.4 7.5 4.6 1.8 1 0 0 1 1 1 0 Life-span regulatory factor MFS_1 PF07690.11 EAQ92694.1 - 5.2e-17 61.5 8.9 6.8e-17 61.2 6.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2784 PF10861.3 EAQ92694.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) DUF1275 PF06912.6 EAQ92695.1 - 5.5e-49 166.2 16.7 6.6e-49 165.9 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ribosomal_L34 PF00468.12 EAQ92695.1 - 0.42 10.3 3.3 2.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L34 Helicase_C PF00271.26 EAQ92696.1 - 1.7e-20 72.6 0.1 9.1e-19 67.1 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 EAQ92696.1 - 4e-08 32.9 0.1 7.5e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 EAQ92696.1 - 1.8e-05 24.3 0.0 7.7e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KAR9 PF08580.5 EAQ92698.1 - 8.6e-151 503.5 0.2 8.6e-151 503.5 0.2 2.0 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 EAQ92698.1 - 0.034 14.5 7.6 0.43 11.0 0.1 4.2 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Ank_2 PF12796.2 EAQ92699.1 - 9.4e-47 157.2 16.1 9.8e-17 61.0 0.1 8.5 4 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ92699.1 - 4.7e-39 130.2 13.2 4e-06 26.3 0.0 11.7 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.1 EAQ92699.1 - 3.1e-29 100.3 11.1 1.7e-05 24.8 0.0 11.3 10 2 2 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92699.1 - 8.6e-29 96.7 10.2 0.00031 20.6 0.0 12.1 13 0 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.1 EAQ92699.1 - 5.1e-25 87.3 10.8 5.4e-06 26.7 0.1 10.8 10 2 3 13 13 13 5 Ankyrin repeats (many copies) PhrC_PhrF PF11131.3 EAQ92700.1 - 6.8 6.3 5.9 55 3.4 2.1 2.4 2 0 0 2 2 2 0 Rap-phr extracellular signalling Sod_Cu PF00080.15 EAQ92701.1 - 2.2e-14 53.8 0.0 2.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EAQ92701.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 CHRD domain Aminotran_5 PF00266.14 EAQ92702.1 - 2e-05 23.4 0.0 5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DUF202 PF02656.10 EAQ92707.1 - 0.00054 20.1 0.7 0.001 19.2 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_capsid PF06112.6 EAQ92709.1 - 0.35 10.9 5.7 0.14 12.1 2.3 1.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SOG2 PF10428.4 EAQ92710.1 - 0.036 12.7 2.8 0.18 10.4 1.1 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein GRA6 PF05084.8 EAQ92710.1 - 0.041 13.4 8.7 0.058 12.9 6.0 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Ribosomal_L19e PF01280.15 EAQ92710.1 - 0.076 12.7 2.6 0.13 12.0 1.8 1.3 1 0 0 1 1 1 0 Ribosomal protein L19e API5 PF05918.6 EAQ92710.1 - 5.9 5.2 9.9 7.7 4.8 6.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MAP65_ASE1 PF03999.7 EAQ92710.1 - 7.6 5.0 13.2 10 4.5 9.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DAD PF02109.11 EAQ92711.1 - 1.8e-48 163.3 0.4 2.3e-48 162.9 0.3 1.1 1 0 0 1 1 1 1 DAD family DUF3439 PF11921.3 EAQ92711.1 - 2.1 8.1 10.9 4.6 7.0 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GRASP55_65 PF04495.9 EAQ92712.1 - 1.1e-47 161.5 0.0 8.1e-47 158.6 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EAQ92713.1 - 2.8e-48 163.5 0.0 4.7e-48 162.8 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EAQ92713.1 - 3.9e-09 36.5 0.0 6.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ92713.1 - 2.2e-07 31.4 0.0 3.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EAQ92713.1 - 1.4e-05 24.7 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EAQ92713.1 - 2.7e-05 23.8 0.1 0.00031 20.3 0.1 2.0 1 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EAQ92713.1 - 0.00062 19.2 0.0 0.0023 17.3 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EAQ92713.1 - 0.0066 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAQ92713.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N6_N4_Mtase PF01555.13 EAQ92713.1 - 0.028 13.9 0.0 0.075 12.5 0.0 1.7 2 0 0 2 2 2 0 DNA methylase Methyltransf_11 PF08241.7 EAQ92713.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.12 EAQ92713.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Dopey_N PF04118.9 EAQ92714.1 - 7e-119 396.1 0.0 2.1e-118 394.6 0.0 1.8 2 0 0 2 2 2 1 Dopey, N-terminal HEAT_EZ PF13513.1 EAQ92714.1 - 0.73 10.4 14.2 0.85 10.1 0.7 5.6 5 0 0 5 5 5 0 HEAT-like repeat Mon1 PF03164.9 EAQ92715.1 - 1.3e-106 356.7 0.0 2.5e-105 352.4 0.0 2.3 1 1 0 1 1 1 1 Trafficking protein Mon1 Thioredoxin PF00085.15 EAQ92717.1 - 2.1e-62 207.3 8.7 3.5e-32 110.1 0.4 3.9 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EAQ92717.1 - 5e-53 179.6 3.2 7.2e-38 130.2 0.4 3.5 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAQ92717.1 - 6.9e-12 45.3 0.1 0.00012 22.1 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EAQ92717.1 - 1.8e-11 44.2 4.9 0.00024 21.2 0.1 4.7 2 2 1 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 EAQ92717.1 - 5.5e-11 42.2 3.8 0.00023 20.7 0.0 3.4 3 0 0 3 3 3 3 Redoxin Thioredoxin_7 PF13899.1 EAQ92717.1 - 4.1e-10 39.5 0.4 0.00089 19.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EAQ92717.1 - 5.9e-09 35.6 2.4 0.0024 17.5 0.1 3.5 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 EAQ92717.1 - 8.7e-09 34.6 2.4 1.5e-08 33.8 1.6 1.4 1 0 0 1 1 1 1 Calsequestrin ERp29_N PF07912.8 EAQ92717.1 - 2.7e-05 24.1 3.0 1.3 8.9 0.1 4.3 3 2 0 3 3 3 2 ERp29, N-terminal domain DSBA PF01323.15 EAQ92717.1 - 0.0025 17.4 0.4 0.15 11.5 0.1 2.7 2 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EAQ92717.1 - 0.028 14.4 7.9 0.67 9.9 0.2 3.7 4 2 0 4 4 4 0 Thioredoxin zf-HIT PF04438.11 EAQ92718.1 - 3.9e-09 35.9 5.4 3.9e-09 35.9 3.7 1.6 2 0 0 2 2 2 1 HIT zinc finger SR-25 PF10500.4 EAQ92718.1 - 0.00012 21.6 9.0 0.00012 21.6 6.2 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein MSP1_C PF07462.6 EAQ92718.1 - 6 5.1 9.6 9.8 4.4 6.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RR_TM4-6 PF06459.7 EAQ92718.1 - 9.6 6.0 10.2 15 5.3 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WLM PF08325.5 EAQ92720.1 - 5.9e-50 169.7 0.1 2e-49 168.0 0.1 1.8 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 EAQ92720.1 - 3.4e-08 33.5 0.3 8.1e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 EAQ92720.1 - 0.002 17.1 6.4 0.0065 15.5 4.4 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Ribosomal_60s PF00428.14 EAQ92720.1 - 8.1 6.9 8.4 6.1 7.3 2.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4110 PF13422.1 EAQ92721.1 - 4.7e-28 96.8 0.0 4.7e-28 96.8 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EAQ92721.1 - 1.6e-25 88.5 19.8 5.4e-09 35.9 0.0 7.1 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EAQ92721.1 - 1.9e-20 72.3 18.0 8.8e-05 22.1 0.1 6.9 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EAQ92721.1 - 1.7e-17 62.9 5.6 6.4e-07 29.2 0.0 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EAQ92721.1 - 3.5e-16 58.2 2.0 0.0021 17.7 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EAQ92721.1 - 1.4e-14 53.3 2.3 8.5e-07 28.4 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EAQ92721.1 - 6.9e-13 48.1 5.4 0.00046 20.2 0.1 5.7 6 0 0 6 6 6 2 Kelch motif Peptidase_M1 PF01433.15 EAQ92722.1 - 5.7e-139 463.5 0.0 8.9e-139 462.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EAQ92722.1 - 2.9e-94 315.9 0.1 5e-94 315.1 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EAQ92722.1 - 1.9e-20 73.2 0.3 4.6e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Enolase_C PF00113.17 EAQ92723.1 - 4.8e-153 508.3 0.1 6.4e-153 507.9 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EAQ92723.1 - 1.6e-42 144.5 1.7 2.5e-34 118.0 0.2 2.6 2 1 1 3 3 3 2 Enolase, N-terminal domain MAAL_C PF07476.6 EAQ92723.1 - 0.00024 20.1 0.7 0.046 12.6 0.1 3.0 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EAQ92723.1 - 0.0019 18.6 0.0 0.0049 17.3 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Mad3_BUB1_I PF08311.7 EAQ92724.1 - 3.4e-43 146.4 0.4 9.9e-43 144.9 0.2 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EAQ92724.1 - 1.7e-11 43.7 0.0 5.5e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92724.1 - 0.0031 16.6 0.0 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase AP_endonuc_2 PF01261.19 EAQ92725.1 - 8.4e-29 100.3 1.3 2.6e-28 98.7 0.3 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel TRAUB PF08164.7 EAQ92725.1 - 0.031 14.3 1.0 0.12 12.4 0.7 2.0 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal F-box-like PF12937.2 EAQ92726.1 - 4.5e-05 23.0 0.0 9.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 EAQ92726.1 - 0.026 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) RRM_1 PF00076.17 EAQ92727.1 - 6.6e-12 44.8 0.0 1.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ92727.1 - 7.2e-09 35.5 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ92727.1 - 6.4e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EAQ92727.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Nup35_RRM_2 PF14605.1 EAQ92727.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DEAD PF00270.24 EAQ92728.1 - 3.5e-44 150.2 3.0 3.8e-44 150.1 1.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ92728.1 - 1.3e-27 95.4 0.3 6.6e-27 93.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ92728.1 - 0.00073 19.4 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EAQ92728.1 - 0.0031 17.1 0.1 0.012 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EAQ92728.1 - 0.012 14.6 0.3 0.025 13.6 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 EAQ92728.1 - 0.018 15.1 0.4 0.08 13.0 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAQ92728.1 - 0.046 13.4 0.1 0.16 11.7 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 EAQ92728.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP tRNA-synt_1b PF00579.20 EAQ92728.1 - 0.065 12.3 0.0 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 EAQ92728.1 - 0.08 12.6 0.2 0.53 10.0 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.1 EAQ92729.1 - 5.1e-18 65.4 0.1 3.8e-17 62.6 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EAQ92729.1 - 3.9e-10 39.9 0.0 1e-09 38.6 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EAQ92729.1 - 0.0026 17.4 0.1 0.0065 16.1 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAQ92729.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain Cupin_4 PF08007.7 EAQ92729.1 - 0.071 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein DUF1771 PF08590.5 EAQ92730.1 - 2.8e-14 52.8 11.0 8.9e-14 51.2 7.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EAQ92730.1 - 9e-10 38.6 0.0 3.2e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EAQ92730.1 - 0.0013 18.3 0.3 0.0028 17.2 0.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.10 EAQ92730.1 - 0.019 14.4 0.0 0.051 13.1 0.0 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region HBS1_N PF08938.5 EAQ92730.1 - 0.019 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus SNARE_assoc PF09335.6 EAQ92731.1 - 6.4e-12 45.7 9.5 6.4e-12 45.7 6.6 2.6 3 1 1 4 4 4 1 SNARE associated Golgi protein Abhydrolase_6 PF12697.2 EAQ92733.1 - 8.8e-14 51.9 1.6 3e-12 46.9 1.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ92733.1 - 4.2e-11 42.8 0.0 2.2e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ92733.1 - 3.5e-07 30.0 0.0 9.2e-06 25.4 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EAQ92733.1 - 0.00029 19.5 0.0 0.00043 18.9 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Esterase PF00756.15 EAQ92733.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EAQ92733.1 - 0.012 14.8 0.1 0.11 11.6 0.1 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family BTB PF00651.26 EAQ92734.1 - 2.5e-07 30.6 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.24 EAQ92735.1 - 6.5e-17 61.5 0.0 2.4e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.1 EAQ92735.1 - 6.3e-05 23.0 0.2 0.0002 21.4 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 EAQ92735.1 - 0.0019 18.0 0.0 0.0053 16.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BAH PF01426.13 EAQ92737.1 - 6.7e-15 54.8 0.0 1.5e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 EAQ92737.1 - 1.5e-10 41.0 0.1 1.5e-10 41.0 0.1 3.9 3 2 0 3 3 3 1 PHD-zinc-finger like domain PHD_2 PF13831.1 EAQ92737.1 - 2.9e-09 36.0 4.4 2.9e-09 36.0 3.0 3.7 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EAQ92737.1 - 4.2e-06 26.3 6.9 4.2e-06 26.3 4.8 5.1 6 0 0 6 6 6 1 PHD-finger zf-HC5HC2H PF13771.1 EAQ92737.1 - 9e-05 22.5 0.1 9e-05 22.5 0.1 4.4 4 1 0 4 4 4 1 PHD-like zinc-binding domain C1_1 PF00130.17 EAQ92737.1 - 0.0009 18.9 1.8 0.0009 18.9 1.2 4.4 4 1 1 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.26 EAQ92737.1 - 0.0088 16.0 1.5 0.052 13.6 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Prok-RING_1 PF14446.1 EAQ92737.1 - 0.0091 15.7 1.7 0.0091 15.7 1.2 3.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 DnaJ PF00226.26 EAQ92739.1 - 4.9e-27 93.4 1.6 8.2e-27 92.7 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EAQ92739.1 - 2.8e-21 75.2 0.0 1.6e-18 66.3 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EAQ92739.1 - 3.1e-13 49.5 17.1 5.5e-13 48.7 11.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EAQ92739.1 - 0.09 12.4 9.2 0.29 10.8 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EAQ92739.1 - 0.29 10.9 6.1 5.4 6.8 0.6 2.5 3 0 0 3 3 3 0 zinc-ribbons DUF2614 PF11023.3 EAQ92739.1 - 1.6 8.5 5.3 16 5.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) WD40 PF00400.27 EAQ92740.1 - 4.5e-05 23.1 0.1 0.0012 18.6 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat SOG2 PF10428.4 EAQ92740.1 - 0.37 9.4 7.0 0.48 9.0 4.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L10 PF00466.15 EAQ92741.1 - 3.8e-25 87.7 0.1 7.9e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EAQ92741.1 - 7.1e-15 55.1 6.6 1.5e-14 54.1 2.4 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.16 EAQ92742.1 - 2.7e-76 256.0 0.0 1.1e-75 254.0 0.0 1.9 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.15 EAQ92742.1 - 1e-18 67.3 0.0 4e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.13 EAQ92742.1 - 1.2e-15 57.8 0.0 1.3e-14 54.4 0.0 2.3 1 1 0 1 1 1 1 MutS domain III AAA_22 PF13401.1 EAQ92742.1 - 0.0051 16.9 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EAQ92742.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CobA_CobO_BtuR PF02572.10 EAQ92742.1 - 0.035 13.7 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP MutS_IV PF05190.13 EAQ92742.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV AAA_14 PF13173.1 EAQ92742.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAQ92742.1 - 0.17 12.2 0.1 0.65 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain SGT1 PF07093.6 EAQ92743.1 - 0.0009 17.7 0.2 0.0011 17.4 0.1 1.1 1 0 0 1 1 1 1 SGT1 protein Gly-zipper_OmpA PF13436.1 EAQ92743.1 - 0.0011 18.6 14.1 0.0012 18.4 8.5 2.1 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain DUF1676 PF07898.8 EAQ92743.1 - 0.087 13.1 1.5 3.7 7.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) Nop14 PF04147.7 EAQ92743.1 - 1.2 6.9 18.8 1.7 6.4 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 EAQ92743.1 - 10 5.1 17.8 15 4.6 12.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glyco_hydro_38 PF01074.17 EAQ92744.1 - 1.2e-90 303.5 0.1 2.1e-90 302.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EAQ92744.1 - 2.7e-64 217.6 0.3 1.4e-63 215.3 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EAQ92744.1 - 1.4e-25 89.3 0.0 3.2e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain 7TMR-DISMED2 PF07696.6 EAQ92744.1 - 0.25 10.7 2.8 0.31 10.4 0.3 2.4 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Nop14 PF04147.7 EAQ92745.1 - 4.1e-274 911.6 27.1 5e-274 911.3 18.8 1.1 1 0 0 1 1 1 1 Nop14-like family CAP_GLY PF01302.20 EAQ92747.1 - 1.6e-16 59.7 0.2 4.2e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.4 EAQ92747.1 - 0.011 15.1 16.0 0.14 11.5 0.7 3.4 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Bacillus_HBL PF05791.6 EAQ92747.1 - 0.13 11.5 7.5 0.6 9.4 0.6 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.4 EAQ92747.1 - 0.15 12.2 14.1 0.051 13.7 1.5 3.2 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EAQ92747.1 - 0.16 11.5 22.7 0.23 10.9 0.3 4.9 4 1 1 5 5 5 0 Septum formation initiator AAA_13 PF13166.1 EAQ92747.1 - 0.22 9.9 21.1 0.075 11.4 8.5 2.2 1 1 1 2 2 2 0 AAA domain TMF_DNA_bd PF12329.3 EAQ92747.1 - 0.25 11.1 42.0 2.1 8.1 4.6 5.9 4 1 2 6 6 6 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EAQ92747.1 - 0.37 11.0 13.3 2.1 8.6 2.0 3.1 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EAQ92747.1 - 0.51 8.9 28.6 0.17 10.5 3.1 3.1 1 1 1 3 3 3 0 Spc7 kinetochore protein Pkip-1 PF06878.6 EAQ92747.1 - 0.73 9.6 10.4 0.62 9.9 1.4 2.3 1 1 1 2 2 2 0 Pkip-1 protein Reo_sigmaC PF04582.7 EAQ92747.1 - 0.76 8.8 11.3 0.78 8.8 1.1 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Glutaredoxin2_C PF04399.8 EAQ92747.1 - 1.2 8.7 9.6 1.8 8.1 0.7 2.7 3 0 0 3 3 2 0 Glutaredoxin 2, C terminal domain FliD_N PF02465.13 EAQ92747.1 - 1.3 9.4 9.0 6.9 7.1 0.9 2.9 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Cauli_AT PF03233.8 EAQ92747.1 - 1.9 8.1 5.1 1.4 8.5 0.7 2.4 2 0 0 2 2 2 0 Aphid transmission protein Fzo_mitofusin PF04799.8 EAQ92747.1 - 2.1 7.7 5.7 2.2 7.6 0.7 2.6 2 0 0 2 2 2 0 fzo-like conserved region Glyco_hydro_4C PF11975.3 EAQ92747.1 - 2.3 7.9 6.6 7.3 6.3 0.4 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain PilJ PF13675.1 EAQ92747.1 - 3.4 8.0 19.9 0.087 13.1 2.0 3.9 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Mod_r PF07200.8 EAQ92747.1 - 4.8 7.0 22.1 0.25 11.2 3.1 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.6 EAQ92747.1 - 6 6.2 22.9 0.31 10.4 2.2 3.2 2 2 0 3 3 3 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 EAQ92747.1 - 7.2 6.3 33.3 0.036 13.8 7.7 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 EAQ92748.1 - 6.1e-26 91.1 0.0 2.4e-15 56.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92748.1 - 5.5e-09 35.4 0.0 0.021 13.8 0.0 3.0 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EAQ92748.1 - 0.0018 17.3 0.0 0.71 8.7 0.0 2.1 2 0 0 2 2 2 2 Kinase-like IU_nuc_hydro PF01156.14 EAQ92749.1 - 5.4e-14 52.1 0.0 1.7e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 EAQ92749.1 - 7.8e-09 35.0 9.1 7.8e-09 35.0 6.3 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF2924 PF11149.3 EAQ92749.1 - 0.058 13.4 0.4 0.058 13.4 0.3 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2924) IMS PF00817.15 EAQ92750.1 - 2.3e-38 131.3 0.0 5e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EAQ92750.1 - 2.2e-17 63.1 0.0 4.6e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EAQ92750.1 - 1.2e-14 54.1 5.5 1.1e-06 28.5 2.7 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EAQ92750.1 - 0.00016 21.4 0.4 0.00098 19.0 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.21 EAQ92750.1 - 0.0032 17.5 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 EAQ92750.1 - 0.012 15.7 0.2 0.054 13.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain PTCB-BRCT PF12738.2 EAQ92750.1 - 0.029 14.2 0.2 0.076 12.8 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain Peptidase_M3 PF01432.15 EAQ92751.1 - 1.7e-101 340.5 0.0 4.7e-101 339.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M3 DUF2317 PF10079.4 EAQ92751.1 - 0.016 13.8 0.1 0.038 12.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Peptidase_M50B PF13398.1 EAQ92751.1 - 0.02 14.3 0.1 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 EAQ92752.1 - 2.4e-40 137.8 2.3 6.1e-40 136.5 0.1 2.0 2 0 0 2 2 2 1 Apolipoprotein O TspO_MBR PF03073.10 EAQ92752.1 - 0.14 11.6 0.5 0.31 10.5 0.3 1.7 1 1 0 1 1 1 0 TspO/MBR family Mito_carr PF00153.22 EAQ92753.1 - 3.4e-49 164.5 0.1 9.2e-22 76.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sod_Fe_C PF02777.13 EAQ92755.1 - 2e-11 43.6 0.0 5.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain SAM_2 PF07647.12 EAQ92756.1 - 0.0024 17.6 0.0 0.0083 15.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAQ92756.1 - 0.025 14.7 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH PF00169.24 EAQ92756.1 - 0.036 14.2 0.0 0.21 11.8 0.0 2.2 1 1 0 1 1 1 0 PH domain PH_9 PF15410.1 EAQ92756.1 - 0.09 12.9 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 EAQ92758.1 - 9.3e-74 248.3 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ92758.1 - 8.1e-08 32.0 5.6 1.3e-07 31.3 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haemadin PF09065.5 EAQ92760.1 - 0.0068 15.9 6.6 0.017 14.7 4.6 1.7 1 0 0 1 1 1 1 Haemadin Plasmodium_Vir PF05795.6 EAQ92760.1 - 0.092 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1517 PF07466.6 EAQ92760.1 - 0.11 11.5 2.9 0.21 10.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RAP1 PF07218.6 EAQ92760.1 - 0.77 7.7 2.0 0.99 7.4 1.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aldo_ket_red PF00248.16 EAQ92763.1 - 1.8e-52 177.9 0.0 2.1e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.9 EAQ92763.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase DUF530 PF04409.7 EAQ92763.1 - 0.098 10.7 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) PIF1 PF05970.9 EAQ92764.1 - 1.4e-11 43.9 0.8 4.1e-06 25.9 0.0 2.8 4 0 0 4 4 4 2 PIF1-like helicase WD40 PF00400.27 EAQ92765.1 - 3.4e-175 562.4 54.9 4.2e-14 51.7 0.1 14.8 14 0 0 14 14 14 13 WD domain, G-beta repeat NACHT PF05729.7 EAQ92765.1 - 1.1e-21 77.2 0.8 3.8e-21 75.4 0.6 1.8 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.7 EAQ92765.1 - 3.8e-21 74.3 25.5 6 6.6 0.0 13.5 13 0 0 13 13 13 12 WD40-like Beta Propeller Repeat DUF1652 PF07865.6 EAQ92765.1 - 9.8e-17 60.3 0.0 2.4 7.8 0.0 12.4 10 3 3 13 13 13 3 Protein of unknown function (DUF1652) PNP_UDP_1 PF01048.15 EAQ92765.1 - 1.8e-14 53.3 0.1 3.1e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily DUF202 PF02656.10 EAQ92765.1 - 8.9e-10 38.6 0.2 8.9e-10 38.6 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Proteasome_A_N PF10584.4 EAQ92765.1 - 1.7e-09 36.8 4.2 1.9e+02 1.4 0.0 12.1 13 0 0 13 13 13 0 Proteasome subunit A N-terminal signature AAA_22 PF13401.1 EAQ92765.1 - 0.011 15.8 0.1 0.3 11.2 0.0 2.7 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAQ92765.1 - 0.34 11.0 0.0 0.82 9.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EAQ92766.1 - 1.2e-57 195.1 0.0 9.6e-57 192.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EAQ92766.1 - 1.3e-55 187.9 0.0 5.2e-55 185.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAQ92766.1 - 8.5e-13 47.8 0.2 7.2e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAQ92766.1 - 2.2e-09 37.2 0.0 1.3e-07 31.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EAQ92766.1 - 1.5e-07 31.3 0.0 4.3e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EAQ92766.1 - 1.4e-06 27.9 0.0 0.59 9.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EAQ92766.1 - 1.3e-05 24.3 0.1 0.0001 21.4 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAQ92766.1 - 5.3e-05 23.3 0.1 0.00092 19.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EAQ92766.1 - 0.0001 21.7 0.0 0.00038 19.8 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EAQ92766.1 - 0.00074 18.9 0.3 0.05 12.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain DEAD PF00270.24 EAQ92766.1 - 0.0038 16.7 0.0 0.062 12.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 EAQ92766.1 - 0.0048 16.5 0.0 0.095 12.3 0.0 2.3 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.1 EAQ92766.1 - 0.0058 16.6 0.1 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Flavi_DEAD PF07652.9 EAQ92766.1 - 0.0067 16.1 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain UvrD_C_2 PF13538.1 EAQ92766.1 - 0.0077 16.3 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 EAQ92766.1 - 0.013 14.4 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EAQ92766.1 - 0.013 14.9 0.1 0.036 13.5 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family UvrD_C PF13361.1 EAQ92766.1 - 0.013 14.9 0.0 2.9 7.2 0.0 2.8 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain Zot PF05707.7 EAQ92766.1 - 0.013 14.9 0.0 0.14 11.6 0.0 2.5 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EAQ92766.1 - 0.015 14.7 0.0 0.072 12.5 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain AAA_5 PF07728.9 EAQ92766.1 - 0.02 14.6 0.0 0.083 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EAQ92766.1 - 0.021 15.0 0.0 0.074 13.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EAQ92766.1 - 0.021 14.2 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 EAQ92766.1 - 0.022 14.0 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein 4HB_MCP_1 PF12729.2 EAQ92766.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TrwB_AAD_bind PF10412.4 EAQ92766.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 EAQ92766.1 - 0.26 12.1 3.7 0.43 11.3 0.7 2.8 3 1 0 3 3 1 0 AAA domain Lzipper-MIP1 PF14389.1 EAQ92767.1 - 0.13 12.3 0.1 0.4 10.8 0.1 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 EAQ92767.1 - 0.35 10.3 0.5 0.64 9.5 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 EAQ92767.1 - 6.6 4.8 6.3 8.6 4.4 4.2 1.4 1 1 0 1 1 1 0 Transmembrane protein HATPase_c PF02518.21 EAQ92768.1 - 3.3e-08 33.2 0.0 9.3e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldedh PF00171.17 EAQ92770.1 - 7.1e-132 440.0 0.1 8.7e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S30AE PF02482.14 EAQ92770.1 - 0.053 13.9 0.1 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Asp PF00026.18 EAQ92771.1 - 1.5e-48 165.7 0.0 1.1e-35 123.4 1.6 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ92771.1 - 3.3e-05 23.9 0.2 6.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAQ92771.1 - 9.2e-05 22.0 0.0 0.00024 20.6 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Peptidase_S8 PF00082.17 EAQ92773.1 - 7.7e-19 67.9 0.0 1.9e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Subtilase family Ank PF00023.25 EAQ92773.1 - 6e-05 22.6 0.1 0.0067 16.1 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 EAQ92773.1 - 0.00041 20.5 0.0 0.048 13.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92773.1 - 0.00077 19.4 0.3 1.4 9.3 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.2 EAQ92773.1 - 0.001 19.3 0.0 0.034 14.4 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ92773.1 - 0.003 18.0 0.0 4.3 7.9 0.0 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ92775.1 - 2e-67 223.5 6.3 6.1e-13 48.9 0.0 8.8 3 1 3 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ92775.1 - 1.3e-43 144.7 23.6 2.7e-05 23.7 0.0 14.3 14 1 1 15 15 15 9 Ankyrin repeat Ank_4 PF13637.1 EAQ92775.1 - 4.2e-39 132.2 14.7 8.8e-06 26.0 0.0 10.4 7 2 4 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92775.1 - 5.3e-35 115.9 12.1 0.0037 17.3 0.0 14.6 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.1 EAQ92775.1 - 7.2e-31 105.5 16.8 7e-05 22.9 0.1 12.5 8 3 6 14 14 14 7 Ankyrin repeats (many copies) DUF676 PF05057.9 EAQ92775.1 - 1.4e-05 24.5 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EAQ92775.1 - 0.0046 16.8 0.1 0.026 14.4 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAQ92775.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein SdiA-regulated PF06977.6 EAQ92775.1 - 0.025 13.5 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 SdiA-regulated ZZ PF00569.12 EAQ92775.1 - 0.32 10.5 7.3 0.75 9.3 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-UBR PF02207.15 EAQ92775.1 - 0.6 9.8 5.2 1.3 8.7 3.6 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) APC_CDC26 PF10471.4 EAQ92776.1 - 9.7e-15 55.0 0.1 9.7e-15 55.0 0.1 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex APC subunit 1 EBV-NA3 PF05009.7 EAQ92776.1 - 0.26 10.4 2.8 0.4 9.9 1.9 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Cwf_Cwc_15 PF04889.7 EAQ92776.1 - 1.1 8.9 5.6 1.8 8.2 3.9 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M1 PF01433.15 EAQ92777.1 - 1.7e-10 40.5 0.0 0.014 14.5 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 SAS4 PF15460.1 EAQ92779.1 - 9.8e-32 108.8 0.0 2.3e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Filament PF00038.16 EAQ92780.1 - 0.0011 18.4 9.9 0.0011 18.4 6.8 6.6 4 2 1 5 5 5 2 Intermediate filament protein RTBV_P46 PF06216.6 EAQ92780.1 - 0.15 10.8 8.3 0.17 10.7 0.6 3.0 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein zf-ZPR1 PF03367.8 EAQ92780.1 - 1.3 8.1 10.6 0.55 9.3 0.3 3.9 3 1 0 3 3 3 0 ZPR1 zinc-finger domain DUF3584 PF12128.3 EAQ92780.1 - 6.5 3.9 85.9 0.01 13.2 22.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) IBR PF01485.16 EAQ92781.1 - 1e-09 38.1 23.6 7.7e-07 28.8 4.0 3.6 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EAQ92781.1 - 0.0028 17.4 6.1 0.0028 17.4 4.2 3.5 3 0 0 3 3 3 1 Ring finger domain 3Beta_HSD PF01073.14 EAQ92782.1 - 4.6e-21 74.7 0.0 3.3e-20 71.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAQ92782.1 - 4.3e-12 45.9 0.0 7.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAQ92782.1 - 5.3e-09 36.3 0.0 1.8e-07 31.3 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EAQ92782.1 - 7.1e-06 25.1 0.0 2.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EAQ92782.1 - 9.1e-05 22.4 1.2 0.00033 20.6 0.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ92782.1 - 0.0045 16.6 0.5 0.014 15.0 0.4 1.7 1 1 0 1 1 1 1 KR domain Peptidase_C97 PF05903.9 EAQ92783.1 - 3.8e-32 111.1 0.0 4.8e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EAQ92783.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.8 EAQ92784.1 - 3.4e-33 113.2 0.1 9.6e-33 111.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EAQ92784.1 - 7.1e-12 45.3 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ92784.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EAQ92784.1 - 0.002 17.9 0.0 0.0054 16.5 0.0 1.8 1 0 0 1 1 1 1 TGS domain PPAK PF02818.10 EAQ92784.1 - 0.014 15.2 1.2 0.043 13.7 0.9 1.9 1 0 0 1 1 1 0 PPAK motif BetaGal_dom3 PF13363.1 EAQ92784.1 - 0.026 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 MobB PF03205.9 EAQ92784.1 - 0.038 13.7 0.2 3.3 7.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EAQ92784.1 - 0.07 13.0 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EAQ92784.1 - 0.17 12.2 4.4 1.2 9.4 3.0 2.1 1 1 0 1 1 1 0 AAA domain VPS9 PF02204.13 EAQ92785.1 - 3.9e-21 75.0 0.0 7.7e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EAQ92785.1 - 1.1e-17 63.6 0.0 5e-11 42.4 0.0 5.6 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ92785.1 - 6.7e-11 42.3 0.6 0.0013 19.1 0.0 5.5 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAQ92785.1 - 2.3e-10 40.6 0.1 0.0011 19.2 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAQ92785.1 - 4.5e-07 29.4 0.2 0.78 10.1 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.19 EAQ92785.1 - 1.7e-05 24.5 0.1 5.1e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.25 EAQ92785.1 - 2.9e-05 23.6 1.3 0.046 13.5 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat TACC PF05010.9 EAQ92785.1 - 0.16 11.7 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF4623 PF15416.1 EAQ92785.1 - 0.34 9.2 0.0 0.72 8.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) ketoacyl-synt PF00109.21 EAQ92786.1 - 6.4e-74 248.6 1.1 1.5e-73 247.4 0.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EAQ92786.1 - 1.3e-39 136.1 0.3 7.3e-29 100.8 0.0 2.5 1 1 1 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EAQ92786.1 - 1.6e-37 127.9 1.8 2e-37 127.6 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EAQ92786.1 - 7.7e-17 61.5 0.3 1.9e-07 30.7 0.1 3.4 2 1 1 3 3 3 3 Acyl transferase domain Methyltransf_12 PF08242.7 EAQ92786.1 - 1.5e-07 31.7 0.0 5.5e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ92786.1 - 1.2e-06 28.3 0.0 3.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EAQ92786.1 - 1.6e-05 25.0 0.0 0.00013 22.1 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EAQ92786.1 - 0.00024 20.7 0.0 0.00053 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ92786.1 - 0.00031 21.1 0.0 0.00089 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EAQ92786.1 - 0.011 14.7 1.3 0.021 13.7 0.1 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain adh_short PF00106.20 EAQ92787.1 - 1.5e-15 57.4 8.1 1.5e-15 57.4 5.6 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ92787.1 - 2.8e-10 40.1 1.2 2.8e-10 40.1 0.8 1.5 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ92787.1 - 0.014 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAQ92787.1 - 0.031 13.7 0.0 0.068 12.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAQ92787.1 - 0.075 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DNA_pol_B_palm PF14792.1 EAQ92789.1 - 9.9e-31 106.1 0.0 1.8e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EAQ92789.1 - 1.8e-22 78.7 0.1 1.5e-21 75.7 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 EAQ92789.1 - 1.3e-18 66.9 0.2 2.9e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EAQ92789.1 - 1.3e-15 56.7 0.0 2.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 EAQ92789.1 - 0.026 14.8 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain RR_TM4-6 PF06459.7 EAQ92789.1 - 7.4 6.3 7.3 4.8 6.9 1.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Mob1_phocein PF03637.12 EAQ92790.1 - 1.5e-40 138.7 1.8 1.6e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Methyltransf_31 PF13847.1 EAQ92791.1 - 4.3e-13 49.1 0.1 7.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EAQ92791.1 - 2.1e-11 43.4 0.0 2.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EAQ92791.1 - 2.5e-11 43.2 0.0 3.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EAQ92791.1 - 1.2e-09 38.7 0.0 3.2e-09 37.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ92791.1 - 7.8e-09 35.5 0.0 2.3e-08 34.0 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ92791.1 - 5.8e-08 33.1 0.0 1.5e-07 31.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EAQ92791.1 - 2.1e-07 29.9 0.1 3.2e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EAQ92791.1 - 3.2e-06 27.4 0.0 8.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ92791.1 - 6.3e-06 25.9 0.0 1.5e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAQ92791.1 - 8.2e-06 25.3 0.1 1.6e-05 24.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase small domain FtsJ PF01728.14 EAQ92791.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EAQ92791.1 - 0.00023 21.6 0.0 0.00045 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAQ92791.1 - 0.00024 20.3 0.0 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EAQ92791.1 - 0.01 15.2 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EAQ92791.1 - 0.011 15.3 0.1 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 EAQ92791.1 - 0.015 14.8 0.2 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EAQ92791.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EAQ92791.1 - 0.027 13.6 0.0 0.064 12.4 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EAQ92791.1 - 0.029 13.4 0.1 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EAQ92791.1 - 0.042 13.1 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.10 EAQ92791.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 EAQ92791.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PGM_PMM_II PF02879.11 EAQ92792.1 - 4.3e-12 46.2 0.1 2.2e-11 43.9 0.0 2.3 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EAQ92792.1 - 7.2e-10 38.7 0.2 1.7e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.11 EAQ92792.1 - 2.1e-09 37.0 0.1 8.1e-08 31.8 0.0 2.4 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EAQ92792.1 - 0.02 14.9 0.1 0.075 13.0 0.0 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ERCC4 PF02732.10 EAQ92793.1 - 2.3e-33 114.9 0.1 3.5e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EAQ92793.1 - 0.00031 20.8 0.0 0.00081 19.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Roughex PF06020.6 EAQ92793.1 - 0.16 10.5 1.0 0.28 9.8 0.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Lum_binding PF00677.12 EAQ92794.1 - 1.3e-34 117.9 0.0 1.2e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Glyco_transf_17 PF04724.8 EAQ92795.1 - 1.1e-28 100.3 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 SecG PF03840.9 EAQ92795.1 - 0.15 11.8 0.2 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Peptidase_C15 PF01470.12 EAQ92796.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Oxidored_FMN PF00724.15 EAQ92797.1 - 8.9e-71 238.6 0.0 9.1e-68 228.7 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family XPG_N PF00752.12 EAQ92800.1 - 6.6e-32 109.7 0.0 1.3e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain DUF2403 PF10290.4 EAQ92800.1 - 1e-26 92.8 0.0 2.6e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) DUF2401 PF10287.4 EAQ92800.1 - 6.3e-26 91.3 0.3 1.3e-25 90.2 0.2 1.5 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) XPG_I PF00867.13 EAQ92800.1 - 3.5e-20 71.8 0.0 9.4e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EAQ92800.1 - 0.0067 15.8 1.0 0.0067 15.8 0.7 3.9 3 0 0 3 3 3 1 Ubiquitin interaction motif LSM PF01423.17 EAQ92801.1 - 2.5e-07 30.1 0.0 6.5e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAQ92801.1 - 0.0056 16.5 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Ataxin 2 SM domain Pil1 PF13805.1 EAQ92802.1 - 2.6e-119 397.3 4.2 3.2e-119 397.0 2.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EAQ92802.1 - 0.0079 15.5 1.0 0.014 14.7 0.7 1.4 1 0 0 1 1 1 1 FAM92 protein SET PF00856.23 EAQ92803.1 - 2.2e-21 76.8 4.6 3.7e-21 76.1 0.3 3.2 2 1 0 2 2 2 1 SET domain WD40 PF00400.27 EAQ92804.1 - 1.5e-11 43.6 4.8 0.47 10.4 0.0 9.4 10 0 0 10 10 10 5 WD domain, G-beta repeat SUR7 PF06687.7 EAQ92805.1 - 2.8e-40 138.1 6.9 3.3e-40 137.9 4.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2715 PF10895.3 EAQ92805.1 - 0.059 12.8 0.6 0.1 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2715) PT-VENN PF04829.8 EAQ92805.1 - 4.4 6.9 13.5 15 5.2 5.7 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Metallophos PF00149.23 EAQ92807.1 - 1.5e-40 138.7 0.2 2e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_transf_22 PF03901.12 EAQ92808.1 - 1.3e-27 96.8 8.3 1.7e-27 96.4 5.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3522 PF12036.3 EAQ92808.1 - 0.036 13.8 0.2 0.077 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Serglycin PF04360.7 EAQ92808.1 - 0.11 12.2 0.2 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Serglycin F_actin_cap_B PF01115.12 EAQ92809.1 - 2.6e-108 360.7 0.0 3e-108 360.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit P3A PF08727.6 EAQ92809.1 - 0.052 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like Epimerase PF01370.16 EAQ92810.1 - 1.5e-18 67.1 0.0 2.1e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ92810.1 - 1.6e-06 27.2 0.0 2.8e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EAQ92810.1 - 1e-05 25.5 0.0 3.1e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAQ92810.1 - 0.011 15.7 0.0 0.064 13.2 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EAQ92810.1 - 0.012 14.3 0.0 0.032 12.9 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAQ92810.1 - 0.062 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Spindle_Spc25 PF08234.7 EAQ92812.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 Chromosome segregation protein Spc25 Mito_carr PF00153.22 EAQ92813.1 - 4.1e-52 173.8 8.2 2e-19 69.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_28 PF03033.15 EAQ92814.1 - 2.1e-22 79.3 0.1 5.6e-15 55.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EAQ92814.1 - 4.4e-06 25.5 0.3 7.2e-06 24.8 0.2 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EAQ92814.1 - 0.00048 19.8 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain SnoaL_4 PF13577.1 EAQ92815.1 - 1.7e-15 57.0 0.0 2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.1 EAQ92816.1 - 4.5e-23 82.2 0.1 9.4e-23 81.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EAQ92816.1 - 8.3e-13 48.1 0.0 5.1e-12 45.5 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAQ92816.1 - 8.4e-06 25.3 0.0 0.00041 19.8 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAQ92816.1 - 9.6e-06 25.6 0.0 3e-05 23.9 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ92816.1 - 2.1e-05 24.2 0.0 4.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EAQ92816.1 - 6e-05 22.1 0.0 9.2e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EAQ92816.1 - 0.00058 20.2 0.0 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EAQ92816.1 - 0.011 14.6 0.0 0.025 13.4 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EAQ92816.1 - 0.033 14.4 0.0 0.082 13.2 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PAF-AH_p_II PF03403.8 EAQ92817.1 - 7.2e-52 175.9 0.0 1e-24 86.5 0.0 4.0 4 0 0 4 4 4 3 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EAQ92817.1 - 2.1e-14 53.4 0.1 1.3e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ92817.1 - 7.1e-08 32.6 0.0 2e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EAQ92817.1 - 5.9e-05 22.0 0.0 0.0056 15.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 EAQ92817.1 - 0.0005 18.9 0.0 0.0087 14.8 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EAQ92817.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Mito_carr PF00153.22 EAQ92820.1 - 1.5e-25 88.7 0.1 8.3e-13 47.8 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial carrier protein DUF1708 PF08101.6 EAQ92821.1 - 3.9e-135 450.9 0.0 5e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.14 EAQ92822.1 - 9.8e-27 93.2 0.1 1.5e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Lectin_legB PF00139.14 EAQ92822.1 - 0.032 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Legume lectin domain CDC27 PF09507.5 EAQ92822.1 - 0.032 13.4 0.5 0.032 13.4 0.4 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Inhibitor_I24 PF10465.4 EAQ92822.1 - 0.079 12.6 0.5 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 PinA peptidase inhibitor Metallophos PF00149.23 EAQ92823.1 - 3.8e-15 55.8 2.1 1.3e-14 54.1 1.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 EAQ92824.1 - 5.7e-86 288.1 0.0 8e-86 287.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ92824.1 - 4.1e-74 248.9 0.0 8.6e-74 247.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAQ92824.1 - 8.1e-23 80.1 0.1 2.1e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EAQ92824.1 - 9.7e-21 73.9 0.0 1.7e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain RRF PF01765.14 EAQ92827.1 - 5.3e-30 104.0 0.1 6.9e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor PHD PF00628.24 EAQ92828.1 - 0.0045 16.6 2.5 0.012 15.3 1.7 1.7 1 0 0 1 1 1 1 PHD-finger A2M_N PF01835.14 EAQ92828.1 - 0.087 13.0 0.4 0.5 10.6 0.0 2.3 3 0 0 3 3 3 0 MG2 domain ATG22 PF11700.3 EAQ92829.1 - 1.6e-188 627.0 12.3 2.5e-188 626.4 8.5 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EAQ92829.1 - 4.1e-05 22.4 44.0 0.018 13.7 4.9 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1469 PF07332.6 EAQ92829.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF3602 PF12223.3 EAQ92830.1 - 2e-17 63.3 10.2 1.2e-13 51.2 3.5 3.2 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) FAA_hydrolase PF01557.13 EAQ92832.1 - 4.3e-61 206.1 0.1 5.9e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3724 PF12521.3 EAQ92832.1 - 0.21 11.3 1.1 0.77 9.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) Sugar_tr PF00083.19 EAQ92834.1 - 2.7e-81 273.4 17.7 3.4e-81 273.1 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ92834.1 - 9.1e-28 96.9 18.9 1.3e-27 96.4 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EAQ92834.1 - 5.5e-05 21.5 3.1 0.00021 19.6 0.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EAQ92834.1 - 0.00031 19.2 3.2 0.00031 19.2 2.2 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MutS_V PF00488.16 EAQ92835.1 - 1.1e-78 263.9 0.0 2.4e-78 262.7 0.0 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EAQ92835.1 - 7.5e-38 130.3 0.6 1.2e-37 129.7 0.4 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EAQ92835.1 - 1.4e-29 102.4 0.4 3.1e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EAQ92835.1 - 5.1e-10 39.5 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EAQ92835.1 - 9.7e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV zf-C2H2 PF00096.21 EAQ92836.1 - 0.11 12.9 1.6 0.23 11.8 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ92836.1 - 3.6 8.1 5.1 0.48 10.8 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Prenyltrans PF00432.16 EAQ92837.1 - 2.3e-55 183.7 8.1 3.5e-12 45.6 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAQ92837.1 - 6.8e-37 126.3 0.0 3.1e-14 53.3 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAQ92837.1 - 5e-12 45.7 0.0 9.7e-06 25.5 0.0 2.5 2 1 0 2 2 2 2 Prenyltransferase-like RhoGAP PF00620.22 EAQ92838.1 - 4.6e-29 100.9 0.0 7.2e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 EAQ92839.1 - 3.8e-56 189.1 0.4 4.4e-56 188.8 0.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) U-box PF04564.10 EAQ92839.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 U-box domain DAP3 PF10236.4 EAQ92840.1 - 8e-102 340.3 0.0 1.1e-101 339.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 EAQ92840.1 - 0.16 11.6 0.0 18 4.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MCM PF00493.18 EAQ92841.1 - 5.1e-132 439.6 0.0 9.9e-132 438.7 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAQ92841.1 - 4.1e-26 91.8 0.8 2.4e-25 89.3 0.4 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAQ92841.1 - 2.9e-07 29.8 0.0 2.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAQ92841.1 - 9.1e-07 28.6 0.0 4.2e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EAQ92841.1 - 0.0073 16.6 0.6 0.031 14.6 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAQ92841.1 - 0.031 13.8 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PSD5 PF07637.6 EAQ92841.1 - 0.13 12.3 0.2 0.45 10.5 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Sigma54_activat PF00158.21 EAQ92841.1 - 0.15 11.5 0.1 1.1 8.6 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.1 EAQ92841.1 - 0.61 10.0 3.8 37 4.2 0.0 3.8 3 1 0 4 4 4 0 AAA ATPase domain AAA PF00004.24 EAQ92842.1 - 4.1e-57 192.0 0.0 1.9e-43 147.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EAQ92842.1 - 8.1e-30 102.7 0.1 1.5e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EAQ92842.1 - 4.1e-11 43.2 8.2 1.4e-06 28.4 0.0 4.3 4 1 1 5 5 4 2 AAA ATPase domain AAA_2 PF07724.9 EAQ92842.1 - 3.6e-07 30.2 0.0 0.0069 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EAQ92842.1 - 2.3e-06 27.2 0.5 0.032 13.9 0.0 4.1 4 0 0 4 4 3 2 Part of AAA domain NACHT PF05729.7 EAQ92842.1 - 2.5e-06 27.2 0.3 0.0056 16.3 0.0 3.5 3 1 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.1 EAQ92842.1 - 5.1e-06 26.5 0.0 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EAQ92842.1 - 5.9e-06 26.0 0.1 0.045 13.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EAQ92842.1 - 8.6e-06 24.9 0.0 0.018 14.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 EAQ92842.1 - 8.6e-06 25.9 1.5 0.24 11.5 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.1 EAQ92842.1 - 2.8e-05 24.0 0.0 0.43 10.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.7 EAQ92842.1 - 3.2e-05 23.0 0.0 0.012 14.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAQ92842.1 - 9.6e-05 23.1 0.9 0.15 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAQ92842.1 - 0.00014 21.7 0.2 0.38 10.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EAQ92842.1 - 0.00019 20.9 0.1 0.44 9.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EAQ92842.1 - 0.00028 21.1 0.1 0.28 11.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAQ92842.1 - 0.00047 19.6 3.5 1.8 7.8 0.1 4.2 2 2 2 4 4 4 1 AAA domain Sigma54_activat PF00158.21 EAQ92842.1 - 0.00078 18.9 0.0 0.046 13.1 0.0 2.5 3 0 0 3 3 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 EAQ92842.1 - 0.00083 18.2 0.1 0.21 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain KaiC PF06745.8 EAQ92842.1 - 0.0033 16.5 0.1 0.78 8.8 0.0 2.4 2 0 0 2 2 2 1 KaiC TIP49 PF06068.8 EAQ92842.1 - 0.0034 16.1 0.0 0.85 8.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 EAQ92842.1 - 0.0036 16.5 0.1 0.65 9.1 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EAQ92842.1 - 0.0045 16.9 0.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EAQ92842.1 - 0.005 15.8 0.3 1.9 7.4 0.0 2.5 1 1 1 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.17 EAQ92842.1 - 0.0051 16.9 0.0 4.1 7.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EAQ92842.1 - 0.011 16.0 0.0 5.8 7.2 0.0 3.0 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EAQ92842.1 - 0.014 14.3 0.1 0.079 11.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EAQ92842.1 - 0.017 14.8 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 EAQ92842.1 - 0.022 14.4 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EAQ92842.1 - 0.022 14.2 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EAQ92842.1 - 0.029 13.8 0.1 0.14 11.6 0.1 2.1 3 0 0 3 3 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EAQ92842.1 - 0.034 13.8 0.0 7.2 6.2 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase Viral_helicase1 PF01443.13 EAQ92842.1 - 0.038 13.4 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EAQ92842.1 - 0.043 12.8 0.0 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EAQ92842.1 - 0.043 13.3 0.4 6.5 6.2 0.2 2.7 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EAQ92842.1 - 0.045 12.6 0.0 0.68 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CobU PF02283.11 EAQ92842.1 - 0.064 12.6 0.8 0.12 11.8 0.0 1.8 2 0 0 2 2 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase KTI12 PF08433.5 EAQ92842.1 - 0.078 12.1 0.0 0.58 9.3 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Gtr1_RagA PF04670.7 EAQ92842.1 - 0.3 10.2 0.0 0.6 9.2 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TrwB_AAD_bind PF10412.4 EAQ92842.1 - 0.46 9.0 1.2 0.87 8.1 0.1 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Ank_2 PF12796.2 EAQ92843.1 - 9e-08 32.3 0.0 5.4e-05 23.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ92843.1 - 0.11 12.7 1.0 8.1 6.8 0.1 3.0 3 1 1 4 4 4 0 Ankyrin repeats (many copies) VTC PF09359.5 EAQ92845.1 - 1.2e-101 339.5 0.6 1.6e-101 339.0 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EAQ92845.1 - 4.7e-28 98.7 1.2 5e-14 52.7 0.0 2.9 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EAQ92845.1 - 8e-12 45.2 3.3 8e-12 45.2 2.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TrmB PF01978.14 EAQ92845.1 - 0.0012 18.4 0.6 0.021 14.5 0.1 2.7 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 EAQ92845.1 - 0.03 14.4 1.0 0.34 11.0 0.0 3.1 4 0 0 4 4 4 0 Winged helix-turn helix Fe_dep_repress PF01325.14 EAQ92845.1 - 0.064 13.2 0.1 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Cys_Met_Meta_PP PF01053.15 EAQ92846.1 - 4.2e-17 61.4 0.0 9.7e-17 60.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EAQ92846.1 - 1.4e-07 30.7 0.0 2.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Hexokinase_2 PF03727.11 EAQ92847.1 - 1.9e-75 253.1 0.0 1.8e-74 250.0 0.0 2.0 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EAQ92847.1 - 2.5e-64 216.3 0.0 7.2e-64 214.8 0.0 1.7 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 EAQ92847.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain SRR1 PF07985.7 EAQ92848.1 - 0.00022 21.0 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 SRR1 PCIF1_WW PF12237.3 EAQ92848.1 - 0.0092 15.2 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain Ribophorin_I PF04597.9 EAQ92849.1 - 6.7e-155 515.8 0.0 7.7e-155 515.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.1 EAQ92850.1 - 2.7e-126 420.2 1.7 3.3e-126 419.9 1.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 MCM PF00493.18 EAQ92851.1 - 2e-38 132.0 0.1 5.4e-21 74.7 0.0 2.0 1 1 1 2 2 2 2 MCM2/3/5 family Clat_adaptor_s PF01217.15 EAQ92852.1 - 6.1e-13 48.6 0.1 1.6e-12 47.3 0.0 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Pkinase PF00069.20 EAQ92853.1 - 5.3e-54 183.0 0.0 7.2e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92853.1 - 4.5e-40 137.3 0.0 6.9e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sua5_yciO_yrdC PF01300.13 EAQ92853.1 - 2.3e-07 30.2 0.1 1.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Telomere recombination Kinase-like PF14531.1 EAQ92853.1 - 0.019 13.9 0.0 0.063 12.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EAQ92853.1 - 0.036 13.1 0.2 0.11 11.6 0.0 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.14 EAQ92855.1 - 7.6e-14 51.5 0.1 4.3e-10 39.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EAQ92855.1 - 0.00015 20.8 0.3 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EAQ92855.1 - 0.00099 18.1 0.1 0.013 14.4 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAQ92855.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 EAQ92855.1 - 0.0052 15.6 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EAQ92855.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ92855.1 - 0.039 12.8 0.0 0.09 11.6 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAQ92855.1 - 0.091 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAQ92855.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family OmpH PF03938.9 EAQ92856.1 - 2.3e-06 27.6 12.5 4e-06 26.8 8.6 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Pex14_N PF04695.8 EAQ92856.1 - 1.6e-05 24.9 8.5 1.6e-05 24.9 5.9 3.4 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SAGA-Tad1 PF12767.2 EAQ92856.1 - 0.0028 17.3 5.9 0.0028 17.3 4.1 2.7 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF1764 PF08576.5 EAQ92856.1 - 0.0079 16.9 5.1 0.0079 16.9 3.6 2.5 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Ycf1 PF05758.7 EAQ92856.1 - 0.032 11.9 3.1 0.044 11.4 2.1 1.1 1 0 0 1 1 1 0 Ycf1 zf-DHHC PF01529.15 EAQ92856.1 - 0.035 13.4 0.4 0.052 12.9 0.3 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Suf PF05843.9 EAQ92856.1 - 1.7 8.3 20.2 0.071 12.8 7.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 EAQ92856.1 - 1.7 8.4 25.3 3.4 7.4 17.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) eIF-3_zeta PF05091.7 EAQ92856.1 - 6.9 5.1 19.8 0.15 10.6 8.6 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 EAQ92856.1 - 8.3 5.8 15.4 16 4.8 10.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NARP1 PF12569.3 EAQ92856.1 - 9.5 4.8 14.8 18 3.9 10.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Complex1_49kDa PF00346.14 EAQ92857.1 - 7.7e-134 444.8 0.0 9.9e-134 444.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EAQ92858.1 - 1.4e-26 92.8 0.0 3.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EAQ92858.1 - 3.2e-10 38.9 0.0 4.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EAQ92859.1 - 4.2e-39 133.4 0.7 7.5e-39 132.6 0.1 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EAQ92859.1 - 1.7e-31 107.8 0.0 3.1e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EAQ92859.1 - 2.6e-24 84.5 0.3 4.6e-24 83.7 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAQ92859.1 - 4.4e-15 54.7 1.6 4.4e-15 54.7 1.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EAQ92859.1 - 0.00017 21.5 0.0 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EAQ92859.1 - 0.00091 19.3 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.3 EAQ92859.1 - 0.022 14.6 3.1 0.05 13.4 2.1 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein NAD_binding_7 PF13241.1 EAQ92859.1 - 0.028 14.6 0.3 0.064 13.5 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EAQ92859.1 - 0.053 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MoeZ_MoeB PF05237.8 EAQ92859.1 - 0.099 12.2 0.2 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 MoeZ/MoeB domain DAO PF01266.19 EAQ92859.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EAQ92859.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Telomere_reg-2 PF10193.4 EAQ92860.1 - 1.8e-39 134.5 0.0 4e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein TelA PF05816.6 EAQ92862.1 - 0.073 11.7 0.0 0.09 11.4 0.0 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) G-patch PF01585.18 EAQ92863.1 - 7.8e-06 25.5 0.0 4.6e-05 23.1 0.0 2.5 1 1 0 1 1 1 1 G-patch domain TFIIF_alpha PF05793.7 EAQ92863.1 - 0.0022 16.4 42.6 0.0032 15.9 29.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 EAQ92863.1 - 0.041 12.3 46.7 0.055 11.9 32.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTB PF00651.26 EAQ92864.1 - 0.24 11.3 0.0 0.58 10.1 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain RhoGAP PF00620.22 EAQ92866.1 - 1.7e-43 147.8 0.3 6.3e-43 146.0 0.2 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EAQ92866.1 - 1.4e-09 38.1 0.0 3.4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 PH domain Fungal_trans PF04082.13 EAQ92866.1 - 1.2e-06 27.6 0.0 2.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PH_11 PF15413.1 EAQ92866.1 - 1.4e-05 25.3 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Zn_clus PF00172.13 EAQ92866.1 - 0.016 15.0 7.9 0.028 14.3 5.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PH_8 PF15409.1 EAQ92866.1 - 0.077 13.0 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PITH PF06201.8 EAQ92870.1 - 3.9e-44 150.0 0.0 5.5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EAQ92870.1 - 4.7e-26 90.4 0.0 7.9e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EAQ92870.1 - 3.7e-08 33.3 0.1 2.6e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EAQ92870.1 - 1.4e-07 31.7 0.0 3.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EAQ92870.1 - 0.00087 19.2 0.1 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EAQ92870.1 - 0.002 17.6 0.5 0.09 12.3 0.2 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EAQ92870.1 - 0.0027 17.3 0.3 0.048 13.3 0.2 2.2 1 1 0 1 1 1 1 AhpC/TSA family DUF3246 PF11596.3 EAQ92870.1 - 0.0029 16.9 0.1 0.0029 16.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3246) Thioredoxin_9 PF14595.1 EAQ92870.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Serglycin PF04360.7 EAQ92870.1 - 0.024 14.3 0.1 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Serglycin Thioredoxin_3 PF13192.1 EAQ92870.1 - 0.046 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.6 EAQ92870.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 EAQ92870.1 - 0.063 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_6 PF13848.1 EAQ92870.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 EAQ92873.1 - 2.2e-27 95.6 36.8 2.2e-27 95.6 25.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ92873.1 - 3.5e-10 39.0 23.5 1.7e-09 36.8 16.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAQ92873.1 - 0.00018 19.8 2.2 0.0015 16.7 1.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Corona_nucleoca PF00937.13 EAQ92874.1 - 0.016 14.1 8.8 0.019 13.9 6.1 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Zip PF02535.17 EAQ92874.1 - 0.042 12.8 8.3 0.052 12.5 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FRG2 PF15315.1 EAQ92874.1 - 0.11 12.5 14.0 0.13 12.1 9.7 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF2201_N PF13203.1 EAQ92874.1 - 1 8.4 6.4 1.3 8.1 4.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PRA1 PF03208.14 EAQ92875.1 - 3.1e-30 104.5 3.1 4.6e-30 104.0 2.1 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF2911 PF11138.3 EAQ92877.1 - 0.06 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) YbjQ_1 PF01906.12 EAQ92878.1 - 3e-28 98.3 0.3 3.5e-28 98.0 0.2 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.16 EAQ92879.1 - 8.1e-108 360.1 0.1 1.1e-107 359.7 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EAQ92879.1 - 5.9e-55 185.7 1.8 1.1e-54 184.9 1.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ92879.1 - 5.1e-09 36.0 0.4 6.1e-08 32.5 0.1 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ92879.1 - 9.6e-07 28.9 0.0 3.8e-05 23.6 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EAQ92879.1 - 1.2e-06 28.1 1.4 2.1e-05 24.1 0.6 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 EAQ92879.1 - 0.04 12.2 0.0 0.069 11.4 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Methyltransf_11 PF08241.7 EAQ92880.1 - 4.8e-19 68.6 0.0 1.3e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ92880.1 - 8.5e-15 54.6 0.0 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ92880.1 - 1.4e-13 50.9 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.5 EAQ92880.1 - 7.5e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_25 PF13649.1 EAQ92880.1 - 1e-08 35.4 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ92880.1 - 1.7e-08 33.8 0.0 2.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EAQ92880.1 - 1.9e-08 34.6 0.0 5.7e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EAQ92880.1 - 2.9e-08 33.1 0.0 4.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EAQ92880.1 - 2.4e-06 28.1 0.0 4.7e-06 27.1 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ92880.1 - 1.3e-05 25.2 0.1 3.3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EAQ92880.1 - 0.0048 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EAQ92880.1 - 0.0093 15.3 0.0 0.024 13.9 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EAQ92880.1 - 0.012 14.3 0.0 0.023 13.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 EAQ92880.1 - 0.019 14.5 0.0 0.19 11.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EAQ92880.1 - 0.079 13.7 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EAQ92880.1 - 0.08 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ATP-synt_ab PF00006.20 EAQ92884.1 - 1.1e-22 80.5 0.1 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EAQ92884.1 - 9.8e-05 22.4 0.3 0.00022 21.3 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EAQ92885.1 - 5.7e-28 97.6 0.4 2.1e-27 95.8 0.1 1.8 1 1 1 2 2 2 2 ATP synthase alpha/beta chain, C terminal domain Tex_N PF09371.5 EAQ92885.1 - 0.085 12.1 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Mannosyl_trans3 PF11051.3 EAQ92888.1 - 3.5e-53 180.7 0.0 1.4e-52 178.6 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Carb_kinase PF01256.12 EAQ92889.1 - 1.4e-08 34.3 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Carb_kinase PF01256.12 EAQ92890.1 - 1.3e-11 44.2 0.1 1.8e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Surfac_D-trimer PF09006.6 EAQ92891.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Ribosomal_L5_C PF00673.16 EAQ92892.1 - 3.6e-22 77.8 0.0 5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EAQ92892.1 - 3.7e-20 71.4 0.1 9.8e-20 70.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 MPC PF03650.8 EAQ92893.1 - 6.6e-33 113.1 0.1 1.2e-32 112.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EAQ92893.1 - 1.5e-17 62.8 0.0 2.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain PYC_OADA PF02436.13 EAQ92894.1 - 2e-65 219.9 0.0 3.5e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_D2 PF02786.12 EAQ92894.1 - 5.6e-55 185.8 0.4 4.9e-52 176.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain HMGL-like PF00682.14 EAQ92894.1 - 7.1e-25 88.0 0.0 1.3e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EAQ92894.1 - 6.3e-19 67.3 1.5 1.1e-18 66.6 0.4 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_carb_C PF02785.14 EAQ92894.1 - 2.3e-14 53.2 0.0 8.7e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EAQ92894.1 - 1.4e-11 44.5 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EAQ92894.1 - 2e-10 40.1 1.0 6e-06 25.8 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EAQ92894.1 - 2.3e-06 27.1 0.0 3.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EAQ92894.1 - 1.1e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EAQ92894.1 - 8.9e-05 21.3 0.0 0.0002 20.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon HlyD PF00529.15 EAQ92894.1 - 0.00036 19.9 0.2 0.0079 15.5 0.0 2.3 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EAQ92894.1 - 0.001 19.3 0.1 2.7 8.3 0.0 3.1 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.6 EAQ92894.1 - 0.0015 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EAQ92894.1 - 0.0099 15.0 0.0 1.4 7.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein DUF2118 PF09891.4 EAQ92894.1 - 0.02 14.6 0.2 0.073 12.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 EAQ92894.1 - 0.041 13.5 0.5 0.69 9.6 0.1 2.4 1 1 1 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.6 EAQ92894.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Clathrin PF00637.15 EAQ92895.1 - 5.2e-201 658.3 33.3 2.1e-33 114.8 0.7 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EAQ92895.1 - 5.1e-33 112.7 0.9 2.2e-32 110.7 0.6 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EAQ92895.1 - 2.4e-29 99.5 0.2 0.00013 21.9 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_12 PF13424.1 EAQ92895.1 - 3.4e-05 23.6 1.1 6.2 6.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ92895.1 - 8.2e-05 22.1 4.9 3.8 7.5 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ92895.1 - 5.1 8.0 17.9 35 5.4 0.1 8.7 9 1 2 11 11 11 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 EAQ92896.1 - 2.2e-97 325.8 0.0 3.2e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EAQ92896.1 - 0.005 16.8 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1640 PF07798.6 EAQ92897.1 - 3.1e-64 216.2 7.1 3.9e-64 215.9 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 EAQ92897.1 - 0.093 12.9 10.2 0.47 10.6 6.3 2.4 1 1 0 1 1 1 0 Syntaxin CLAMP PF14769.1 EAQ92897.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Metal_resist PF13801.1 EAQ92897.1 - 7.6 6.5 8.9 0.46 10.4 1.5 2.1 2 0 0 2 2 2 0 Heavy-metal resistance VHP PF02209.14 EAQ92898.1 - 0.047 13.4 0.2 16 5.3 0.0 2.9 3 0 0 3 3 3 0 Villin headpiece domain zf-RING_2 PF13639.1 EAQ92900.1 - 0.0007 19.3 5.6 0.0007 19.3 3.9 2.4 2 0 0 2 2 2 1 Ring finger domain Rad50_zn_hook PF04423.9 EAQ92900.1 - 0.0075 15.7 1.2 0.96 8.9 0.0 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4_2 PF13923.1 EAQ92900.1 - 0.56 10.2 8.5 0.2 11.7 2.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ92900.1 - 2.5 7.8 9.6 0.57 9.8 3.0 2.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EAQ92900.1 - 6.7 6.3 9.3 26 4.4 0.0 3.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EAQ92900.1 - 6.8 6.8 10.8 0.29 11.2 2.6 2.5 2 0 0 2 2 2 0 RING-variant domain Cullin PF00888.17 EAQ92901.1 - 5.2e-121 405.0 0.2 6.7e-121 404.6 0.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAQ92901.1 - 1e-12 47.6 0.6 4.8e-12 45.5 0.2 2.4 2 1 0 2 2 2 1 Cullin protein neddylation domain zf-DNL PF05180.7 EAQ92902.1 - 3.5e-28 97.1 0.2 5.4e-28 96.4 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.14 EAQ92902.1 - 0.073 12.7 0.7 0.39 10.4 0.5 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CSL PF05207.8 EAQ92902.1 - 0.12 11.8 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 CSL zinc finger Pex14_N PF04695.8 EAQ92902.1 - 1.2 9.2 8.4 1.9 8.5 5.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 EAQ92902.1 - 2.1 6.5 13.6 2.5 6.2 9.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YppG PF14179.1 EAQ92902.1 - 5.4 7.6 18.8 8.1 7.0 13.0 1.2 1 0 0 1 1 1 0 YppG-like protein DRIM PF07539.7 EAQ92903.1 - 5.1e-42 142.6 0.0 1.8e-41 140.8 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EAQ92903.1 - 0.0099 15.8 4.4 4 7.7 0.0 6.7 6 0 0 6 6 6 1 HEAT repeat DNA_RNApol_7kD PF03604.8 EAQ92904.1 - 5.9e-06 25.6 0.1 8.7e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit LacI PF00356.16 EAQ92904.1 - 0.0058 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family CwfJ_C_2 PF04676.9 EAQ92905.1 - 4.9e-25 87.8 0.4 1e-24 86.8 0.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EAQ92905.1 - 6.8e-25 87.0 0.0 1.9e-24 85.6 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 ERAP1_C PF11838.3 EAQ92906.1 - 8e-22 77.9 0.2 1.5e-21 77.0 0.1 1.3 1 1 0 1 1 1 1 ERAP1-like C-terminal domain HEAT_2 PF13646.1 EAQ92906.1 - 0.0078 16.4 0.3 0.041 14.1 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats Peptidase_M1 PF01433.15 EAQ92907.1 - 2e-78 264.2 0.0 5.7e-66 223.1 0.0 3.1 1 1 2 3 3 3 3 Peptidase family M1 Peptidase_MA_2 PF13485.1 EAQ92907.1 - 3.4e-16 59.4 0.0 5.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 EAQ92907.1 - 3.4e-11 42.9 0.1 6.3e-10 38.8 0.1 2.3 1 1 0 1 1 1 1 ERAP1-like C-terminal domain GATase PF00117.23 EAQ92907.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Rhodanese PF00581.15 EAQ92909.1 - 5.6e-12 46.0 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DNA_pol_phi PF04931.8 EAQ92911.1 - 6.6e-51 173.0 34.1 2.4e-35 121.5 16.7 3.4 3 0 0 3 3 3 3 DNA polymerase phi EB1 PF03271.12 EAQ92911.1 - 0.041 13.9 0.1 0.4 10.7 0.0 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif Caleosin PF05042.8 EAQ92911.1 - 0.19 11.2 3.5 6.1 6.3 0.1 2.4 2 0 0 2 2 2 0 Caleosin related protein Proteasome PF00227.21 EAQ92912.1 - 1.7e-27 95.9 0.2 6.4e-13 48.4 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EAQ92912.1 - 0.14 11.5 0.3 0.14 11.5 0.2 1.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DnaJ PF00226.26 EAQ92915.1 - 9.8e-17 60.4 0.2 1.6e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.26 EAQ92916.1 - 9.7e-11 41.2 1.3 2.1e-10 40.1 0.9 1.7 1 1 0 1 1 1 1 DnaJ domain Tyrosinase PF00264.15 EAQ92917.1 - 2.7e-47 161.7 0.1 3.6e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2318 PF10080.4 EAQ92919.1 - 0.0096 15.6 1.1 0.0096 15.6 0.7 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2318) A2L_zn_ribbon PF08792.5 EAQ92919.1 - 0.032 13.6 4.5 0.032 13.6 3.1 1.7 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EAQ92919.1 - 0.04 13.1 2.1 0.04 13.1 1.5 2.3 2 1 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EAQ92919.1 - 0.045 13.6 5.2 0.81 9.6 0.0 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 EAQ92919.1 - 0.21 11.1 0.1 0.21 11.1 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EAQ92919.1 - 0.34 10.7 4.1 0.91 9.3 2.9 1.5 1 1 0 1 1 1 0 Double zinc ribbon GMC_oxred_N PF00732.14 EAQ92920.1 - 3.3e-33 115.1 0.0 5.2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ92920.1 - 5.5e-29 101.2 0.3 1.4e-28 100.0 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EAQ92920.1 - 0.00022 20.2 0.1 0.0012 17.8 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ92920.1 - 0.051 13.5 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAQ92920.1 - 0.056 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EAQ92920.1 - 0.086 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Zn_clus PF00172.13 EAQ92921.1 - 3.6e-07 29.9 6.8 8.3e-07 28.8 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EAQ92921.1 - 0.0044 15.6 1.1 0.0058 15.2 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epiglycanin_C PF14654.1 EAQ92925.1 - 0.039 13.9 0.2 0.057 13.4 0.1 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Peptidase_M56 PF05569.6 EAQ92925.1 - 0.047 12.6 0.5 0.057 12.3 0.3 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Herpes_gE PF02480.11 EAQ92925.1 - 0.12 10.6 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E hDGE_amylase PF14701.1 EAQ92926.1 - 1.4e-177 590.8 0.0 1.8e-177 590.4 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EAQ92926.1 - 9.6e-115 383.2 0.0 2.1e-114 382.1 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EAQ92926.1 - 2.5e-87 292.3 0.0 4.6e-87 291.4 0.0 1.5 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EAQ92926.1 - 6.3e-27 93.2 0.0 1.6e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EAQ92926.1 - 0.00031 20.2 0.0 0.74 9.1 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EAQ92927.1 - 3.8e-45 153.4 0.1 6.6e-45 152.6 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EAQ92927.1 - 4e-36 123.9 0.0 6.3e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AIG2_2 PF13772.1 EAQ92928.1 - 1.1e-06 28.6 0.1 9e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 AIG2-like family Hormone_3 PF00159.13 EAQ92928.1 - 0.022 14.7 0.8 0.076 13.0 0.6 2.0 1 0 0 1 1 1 0 Pancreatic hormone peptide Death PF00531.17 EAQ92929.1 - 0.054 13.2 0.4 13 5.6 0.1 2.6 1 1 1 2 2 2 0 Death domain Peptidase_C48 PF02902.14 EAQ92930.1 - 2.3e-14 53.5 0.1 1.2e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.1 EAQ92931.1 - 2.2e-35 121.7 5.4 2.2e-35 121.7 3.7 2.3 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 Gon7 PF08738.5 EAQ92931.1 - 0.016 15.1 0.5 0.038 13.9 0.4 1.6 1 0 0 1 1 1 0 Gon7 family ThiF PF00899.16 EAQ92932.1 - 1.8e-38 131.4 0.0 2.7e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EAQ92932.1 - 9.4e-16 57.1 0.7 3.3e-14 52.2 0.4 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 EAQ92932.1 - 2.2e-13 50.5 0.0 7.5e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 EAQ92932.1 - 2e-05 24.6 0.1 6.9e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EAQ92932.1 - 0.0063 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pam17 PF08566.5 EAQ92933.1 - 8.5e-66 220.9 0.0 1.1e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Chromo PF00385.19 EAQ92934.1 - 6.2e-08 32.1 4.6 6.2e-08 32.1 3.2 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DHDPS PF00701.17 EAQ92935.1 - 1.6e-40 138.5 0.0 2.1e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EAQ92935.1 - 0.012 14.7 0.6 0.018 14.2 0.4 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase PIF1 PF05970.9 EAQ92937.1 - 1.6e-07 30.6 0.1 1.9e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ92937.1 - 0.043 13.3 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain ydhR PF08803.6 EAQ92937.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR AAA_19 PF13245.1 EAQ92937.1 - 0.11 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain MFS_1 PF07690.11 EAQ92939.1 - 1.9e-18 66.3 34.7 1.2e-14 53.8 16.2 3.8 2 2 0 2 2 2 2 Major Facilitator Superfamily DUF3237 PF11578.3 EAQ92941.1 - 6.4e-37 126.1 0.0 9e-37 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EAQ92941.1 - 1.3e-05 24.8 4.5 0.029 14.1 0.2 2.3 2 0 0 2 2 2 2 BED zinc finger DUF605 PF04652.11 EAQ92941.1 - 3.1 7.1 12.6 4 6.7 8.8 1.1 1 0 0 1 1 1 0 Vta1 like HLH PF00010.21 EAQ92943.1 - 2.3e-10 40.0 0.0 9.7e-10 38.0 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IATP PF04568.7 EAQ92944.1 - 0.43 10.6 6.0 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP COPI_C PF06957.6 EAQ92944.1 - 5.6 5.3 6.2 8.3 4.8 4.3 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NAD_binding_10 PF13460.1 EAQ92945.1 - 2.8e-05 24.2 0.0 3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EAQ92945.1 - 0.00025 20.9 0.0 0.00036 20.4 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EAQ92945.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAQ92945.1 - 0.0047 15.8 0.0 0.0062 15.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EAQ92945.1 - 0.0087 15.3 0.0 0.016 14.4 0.0 1.4 1 1 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EAQ92945.1 - 0.023 13.3 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAQ92945.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EAQ92945.1 - 0.06 12.2 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DUF3439 PF11921.3 EAQ92946.1 - 2.1 8.1 9.4 3.7 7.3 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rotamase_2 PF13145.1 EAQ92949.1 - 0.021 15.4 1.3 0.03 14.9 0.9 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain ORC6 PF05460.8 EAQ92949.1 - 0.53 9.3 2.4 0.62 9.1 1.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4360 PF14273.1 EAQ92950.1 - 4.3e-17 62.3 0.6 5.5e-17 62.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Form_Nir_trans PF01226.12 EAQ92951.1 - 2e-30 105.5 7.8 2.2e-27 95.5 5.4 2.0 1 1 0 1 1 1 1 Formate/nitrite transporter Cellulase PF00150.13 EAQ92953.1 - 3.8e-50 170.6 3.9 4.8e-50 170.3 2.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EAQ92953.1 - 4.3e-12 45.4 16.3 4.3e-12 45.4 11.3 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain CHASE4 PF05228.8 EAQ92953.1 - 0.047 13.2 0.1 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 CHASE4 domain Lamp PF01299.12 EAQ92953.1 - 0.23 10.5 3.0 0.43 9.6 0.3 2.0 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Toxin_7 PF05980.7 EAQ92953.1 - 6.1 6.9 6.7 0.8 9.7 0.2 2.5 3 0 0 3 3 3 0 Toxin 7 DUF3243 PF11588.3 EAQ92954.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) KfrA_N PF11740.3 EAQ92954.1 - 7.1 7.1 13.6 67 3.9 9.5 2.3 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Glyco_hydro_61 PF03443.9 EAQ92956.1 - 2.2e-48 164.9 0.6 2.8e-48 164.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Amidoligase_2 PF12224.3 EAQ92958.1 - 5.1e-16 59.0 0.0 8.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme TraV PF09676.5 EAQ92958.1 - 0.16 12.6 2.3 0.38 11.4 1.6 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) AA_permease_2 PF13520.1 EAQ92961.1 - 1.3e-54 185.4 41.1 1.6e-54 185.0 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAQ92961.1 - 4.4e-19 68.1 36.3 6.5e-19 67.6 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease Senescence PF06911.7 EAQ92962.1 - 0.04 13.6 4.3 0.044 13.4 3.0 1.1 1 0 0 1 1 1 0 Senescence-associated protein Myb_DNA-binding PF00249.26 EAQ92963.1 - 0.0073 16.3 0.2 0.0073 16.3 0.1 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 EAQ92967.1 - 5.3e-05 23.2 5.1 0.11 12.9 0.1 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ92967.1 - 0.0013 18.9 7.8 0.04 14.2 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-RING_3 PF14369.1 EAQ92967.1 - 0.031 14.2 0.1 0.092 12.7 0.1 1.8 1 0 0 1 1 1 0 zinc-finger AFT PF08731.6 EAQ92967.1 - 0.045 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Transcription factor AFT RVT_1 PF00078.22 EAQ92968.1 - 2.1e-12 46.8 0.0 3.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 EAQ92969.1 - 1.1e-16 60.1 0.0 3.8e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ92969.1 - 6e-06 26.1 0.1 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ92969.1 - 8.3e-05 22.3 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ecm29 PF13001.2 EAQ92972.1 - 1.3e-66 225.1 0.0 3.5e-66 223.7 0.0 1.8 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EAQ92972.1 - 0.0013 18.6 9.5 0.75 10.0 0.0 7.5 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EAQ92972.1 - 0.063 13.6 0.6 0.48 10.8 0.0 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Thioredoxin_7 PF13899.1 EAQ92973.1 - 7.1e-16 58.0 0.1 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EAQ92973.1 - 2e-08 33.6 0.2 4.2e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EAQ92973.1 - 2.7e-08 33.7 0.0 5.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain SART-1 PF03343.8 EAQ92973.1 - 0.015 13.6 2.2 0.72 8.1 0.4 2.2 2 0 0 2 2 2 0 SART-1 family Thioredox_DsbH PF03190.10 EAQ92973.1 - 0.039 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.20 EAQ92974.1 - 7.5e-59 198.9 0.0 2.1e-58 197.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ92974.1 - 3.3e-41 141.0 0.0 9e-41 139.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ92974.1 - 0.2 10.6 0.0 6.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like PAT1 PF09770.4 EAQ92974.1 - 0.45 8.6 26.1 0.6 8.2 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Iso_dh PF00180.15 EAQ92977.1 - 5.6e-67 226.1 0.0 4.6e-51 173.8 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.3 EAQ92979.1 - 5.7e-17 61.9 6.1 1e-16 61.2 4.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EAQ92979.1 - 7.9e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ92979.1 - 1.5e-07 31.7 0.0 3.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ92979.1 - 2.3e-05 24.0 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAQ92979.1 - 4.6e-05 23.0 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EAQ92979.1 - 0.0002 21.7 0.0 0.00093 19.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ92979.1 - 0.00029 20.5 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ92979.1 - 0.0016 18.9 0.0 0.0041 17.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EAQ92979.1 - 0.0048 16.0 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EAQ92979.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAQ92979.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Serglycin PF04360.7 EAQ92980.1 - 0.01 15.5 2.9 0.015 15.0 2.0 1.3 1 0 0 1 1 1 0 Serglycin FMO-like PF00743.14 EAQ92982.1 - 4.2e-18 64.8 0.0 8.9e-17 60.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EAQ92982.1 - 1.3e-13 51.5 0.0 2.6e-13 50.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAQ92982.1 - 1.2e-09 38.0 0.0 4.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAQ92982.1 - 2.9e-09 36.8 0.0 4.7e-08 32.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ92982.1 - 7.5e-08 32.4 0.0 1.5e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAQ92982.1 - 4.2e-06 25.9 0.0 9.5e-05 21.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EAQ92982.1 - 0.0007 18.5 0.0 0.0016 17.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ92982.1 - 0.0017 18.7 0.0 1.5 9.2 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ92982.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EAQ92982.1 - 0.031 12.7 0.0 0.069 11.6 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EAQ92982.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 EAQ92983.1 - 9.2e-34 116.6 32.2 1.9e-33 115.6 22.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily 2-Hacid_dh PF00389.25 EAQ92985.1 - 1.4e-28 99.0 0.0 2.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 EAQ92985.1 - 5e-13 48.5 0.0 9.9e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dynamin_N PF00350.18 EAQ92986.1 - 1.3e-28 99.9 0.0 3.5e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EAQ92986.1 - 1e-10 40.8 0.0 3.1e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EAQ92986.1 - 8.2e-05 22.5 0.0 0.00039 20.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Phe_tRNA-synt_N PF02912.13 EAQ92986.1 - 0.0026 17.4 0.1 0.0079 15.8 0.0 1.9 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain Miro PF08477.8 EAQ92986.1 - 0.0085 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EAQ92986.1 - 0.016 15.5 0.0 0.055 13.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Urb2 PF10441.4 EAQ92986.1 - 0.13 11.8 0.1 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Urb2/Npa2 family Pneumo_att_G PF05539.6 EAQ92986.1 - 3.3 6.9 5.2 5.7 6.2 3.6 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ank_2 PF12796.2 EAQ92987.1 - 1.3e-28 99.1 0.0 2.1e-07 31.1 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ92987.1 - 2.3e-25 88.4 1.3 0.0073 16.7 0.0 9.0 7 2 2 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.25 EAQ92987.1 - 3.7e-24 83.2 6.1 0.00044 19.9 0.0 9.5 9 1 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 EAQ92987.1 - 4.4e-15 54.2 5.7 0.14 12.4 0.0 9.2 9 1 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.1 EAQ92987.1 - 1.5e-12 47.3 6.0 0.21 11.8 0.0 8.2 8 1 0 8 8 8 4 Ankyrin repeats (many copies) Clp_N PF02861.15 EAQ92987.1 - 0.016 15.1 1.4 16 5.5 0.0 4.4 4 0 0 4 4 4 0 Clp amino terminal domain Ank_2 PF12796.2 EAQ92988.1 - 9.4e-71 234.2 5.9 5.8e-15 55.4 0.0 10.6 3 1 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ92988.1 - 6e-56 185.9 18.3 1.6e-06 28.4 0.0 14.8 10 3 7 17 17 17 15 Ankyrin repeats (many copies) Ank PF00023.25 EAQ92988.1 - 7.6e-54 176.9 36.7 5.3e-09 35.4 0.1 15.8 15 1 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.1 EAQ92988.1 - 9.9e-48 159.0 24.4 8.7e-06 25.8 0.1 15.8 12 4 5 17 17 17 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ92988.1 - 4.7e-44 143.9 11.7 5.5e-05 23.0 0.0 18.2 19 2 1 20 20 20 7 Ankyrin repeat NACHT PF05729.7 EAQ92988.1 - 4.2e-05 23.2 0.0 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DUF221 PF02714.10 EAQ92991.1 - 9.3e-98 327.0 15.2 1.3e-97 326.6 10.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAQ92991.1 - 1.2e-42 145.1 2.1 1.2e-42 145.1 1.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EAQ92991.1 - 7.1e-17 61.6 0.0 1.4e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) PIP49_N PF14875.1 EAQ92991.1 - 0.093 12.3 0.7 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 MutS_V PF00488.16 EAQ92992.1 - 2.7e-72 242.9 0.0 4.4e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAQ92992.1 - 3.4e-27 95.5 1.6 6.7e-27 94.6 1.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EAQ92992.1 - 0.059 13.4 0.5 0.37 10.8 0.2 2.5 2 1 0 2 2 2 0 MutS domain II Aminotran_4 PF01063.14 EAQ92993.1 - 2.6e-20 72.9 0.0 4.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV DUF4222 PF13973.1 EAQ92993.1 - 0.0064 15.8 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4222) PBP PF01161.15 EAQ92993.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Glyco_transf_20 PF00982.16 EAQ92994.1 - 2.6e-164 547.2 0.1 4.1e-164 546.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EAQ92994.1 - 1.9e-33 115.3 0.0 3.8e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EAQ92994.1 - 0.06 12.8 0.4 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain WD40 PF00400.27 EAQ92995.1 - 1.5e-83 271.9 23.1 2e-15 55.9 0.4 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EAQ92995.1 - 1.5e-07 31.3 0.1 0.00061 19.5 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAQ92995.1 - 1.2e-05 23.6 0.7 0.37 8.8 0.0 4.1 3 2 0 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 EAQ92995.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain PD40 PF07676.7 EAQ92995.1 - 0.05 13.2 0.1 6.5 6.5 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FAD_binding_9 PF08021.6 EAQ92995.1 - 0.094 12.6 0.0 1 9.3 0.0 2.6 3 1 0 3 3 3 0 Siderophore-interacting FAD-binding domain DUF1707 PF08044.6 EAQ92996.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) DUF2613 PF11021.3 EAQ92997.1 - 0.17 11.6 3.4 0.38 10.4 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF202 PF02656.10 EAQ92997.1 - 0.35 11.1 3.1 1.6 8.9 2.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Amino_oxidase PF01593.19 EAQ92998.1 - 1.8e-19 70.1 0.1 3.5e-18 65.9 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ92998.1 - 0.00078 19.4 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TPP_enzyme_N PF02776.13 EAQ92999.1 - 3.1e-43 147.2 0.0 7.4e-43 146.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EAQ92999.1 - 6.9e-17 61.4 0.2 5.4e-16 58.5 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAQ92999.1 - 1.6e-15 57.0 0.0 2.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Exo_endo_phos_2 PF14529.1 EAQ93000.1 - 7e-11 41.7 0.0 2.1e-09 37.0 0.0 2.7 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ93000.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ93000.1 - 0.0011 19.3 4.3 0.027 14.8 0.7 2.9 1 1 1 2 2 2 2 SlyX zf-CCHC PF00098.18 EAQ93000.1 - 0.0064 16.3 2.4 0.0064 16.3 1.6 2.4 2 0 0 2 2 1 1 Zinc knuckle CorA PF01544.13 EAQ93000.1 - 0.014 14.4 1.3 0.028 13.4 0.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.6 EAQ93000.1 - 0.19 11.1 1.1 5.4 6.3 0.8 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2968 PF11180.3 EAQ93000.1 - 0.26 10.6 5.7 0.57 9.5 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4226 PF10774.4 EAQ93000.1 - 0.3 11.1 8.1 0.037 14.0 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) Phage_lysis PF03245.8 EAQ93000.1 - 0.33 10.9 7.8 0.084 12.8 1.1 2.8 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Mnd1 PF03962.10 EAQ93000.1 - 0.94 9.1 5.3 0.3 10.7 1.4 1.8 2 0 0 2 2 2 0 Mnd1 family Med9 PF07544.8 EAQ93000.1 - 2.1 8.1 6.6 3.4 7.4 0.7 3.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DNase_NucA_NucB PF14040.1 EAQ93001.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB PhrC_PhrF PF11131.3 EAQ93001.1 - 0.59 9.7 4.8 0.76 9.4 2.7 1.7 1 1 0 1 1 1 0 Rap-phr extracellular signalling Zn_clus PF00172.13 EAQ93002.1 - 0.00053 19.8 6.7 0.0011 18.8 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_psq PF05225.11 EAQ93003.1 - 1.3e-06 27.8 0.3 3.2e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EAQ93003.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EAQ93003.1 - 0.0026 16.9 0.1 0.15 11.2 0.0 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease BrkDBD PF09607.5 EAQ93003.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain AMP-binding PF00501.23 EAQ93004.1 - 1.2e-53 182.0 0.1 4.4e-33 114.2 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme KR PF08659.5 EAQ93004.1 - 1.9e-52 177.5 4.6 2.7e-51 173.8 0.0 3.8 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 EAQ93004.1 - 3.4e-50 170.8 0.0 1.1e-49 169.2 0.0 2.0 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EAQ93004.1 - 4e-49 167.1 0.0 6.1e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EAQ93004.1 - 6.2e-47 159.6 0.0 9.4e-44 149.2 0.0 3.4 2 0 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 EAQ93004.1 - 3.1e-45 154.8 1.5 7.1e-45 153.7 1.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EAQ93004.1 - 1.8e-42 144.9 0.0 8.8e-42 142.7 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein ketoacyl-synt PF00109.21 EAQ93004.1 - 2.2e-32 112.5 0.4 7.3e-32 110.8 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EAQ93004.1 - 7.3e-30 103.2 0.0 3.3e-29 101.1 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EAQ93004.1 - 1e-17 64.0 2.0 3.4e-10 40.0 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site MULE PF10551.4 EAQ93004.1 - 2.4e-17 62.8 0.1 6.8e-17 61.4 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain Methyltransf_12 PF08242.7 EAQ93004.1 - 1.6e-16 60.6 0.0 5.4e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EAQ93004.1 - 7.9e-16 58.2 0.0 1.9e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EAQ93004.1 - 5.7e-13 48.7 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ93004.1 - 6e-13 49.1 0.0 1.9e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EAQ93004.1 - 1.6e-12 47.5 0.0 5.6e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 EAQ93004.1 - 2.5e-11 43.5 0.0 6.7e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ93004.1 - 2.4e-10 40.9 0.0 5.8e-09 36.5 0.0 3.3 2 0 0 2 2 2 1 Methyltransferase domain Transposase_mut PF00872.13 EAQ93004.1 - 2.7e-07 29.4 0.0 5.6e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family 3Beta_HSD PF01073.14 EAQ93004.1 - 8.3e-07 27.9 0.0 0.0012 17.5 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 EAQ93004.1 - 9.5e-06 25.1 0.0 2.8e-05 23.6 0.0 1.7 2 0 0 2 2 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EAQ93004.1 - 5.1e-05 23.5 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ93004.1 - 7.9e-05 21.8 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EAQ93004.1 - 0.00024 20.1 0.0 0.00046 19.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 EAQ93004.1 - 0.00056 19.0 0.2 0.14 11.1 0.0 2.4 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase FAR1 PF03101.10 EAQ93004.1 - 0.0053 17.2 0.1 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF2857 PF11198.3 EAQ93004.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Methyltransf_8 PF05148.10 EAQ93004.1 - 0.49 9.9 0.0 0.92 9.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase ADH_zinc_N PF00107.21 EAQ93005.1 - 2.1e-08 33.7 0.0 3.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ93005.1 - 0.023 14.4 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EAQ93007.1 - 4.6e-31 107.8 0.0 6.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EAQ93007.1 - 1.4e-14 53.7 0.1 3e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAQ93007.1 - 1.1e-06 28.3 0.1 3.4e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EAQ93008.1 - 1.7e-32 112.5 0.0 1.9e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EAQ93010.1 - 7.6e-14 51.9 0.4 1.3e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ93010.1 - 5.7e-06 26.1 0.1 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAQ93010.1 - 0.0045 16.7 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 EAQ93011.1 - 6.8e-11 42.4 1.4 1.3e-10 41.5 0.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ93011.1 - 4e-10 39.6 0.0 2.1e-09 37.2 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EAQ93011.1 - 1.5e-05 23.8 0.0 2.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.8 EAQ93011.1 - 0.0047 16.5 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EAQ93011.1 - 0.017 13.6 0.0 0.032 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EAQ93011.1 - 0.022 13.9 0.0 0.053 12.7 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EAQ93011.1 - 0.031 13.7 0.1 6.5 6.0 0.0 2.7 4 0 0 4 4 4 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EAQ93011.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase HA PF03457.9 EAQ93012.1 - 0.0092 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain UvrD_C_2 PF13538.1 EAQ93012.1 - 0.041 14.0 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Sugar_tr PF00083.19 EAQ93013.1 - 2.2e-78 263.8 22.2 2.6e-78 263.6 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ93013.1 - 9.9e-29 100.1 25.4 1e-27 96.7 10.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EAQ93013.1 - 0.015 13.4 5.0 0.051 11.6 1.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF1228 PF06779.9 EAQ93013.1 - 0.082 12.9 2.6 5.2 7.1 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) AA_permease_2 PF13520.1 EAQ93014.1 - 1.7e-58 198.1 27.4 2.3e-58 197.7 19.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAQ93014.1 - 2.9e-20 72.0 32.5 2.3e-19 69.1 22.5 1.9 1 1 0 1 1 1 1 Amino acid permease ECH PF00378.15 EAQ93014.1 - 0.011 14.8 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family DUF2205 PF10224.4 EAQ93015.1 - 7.2e-10 38.3 0.8 1.2e-09 37.6 0.6 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) MFS_1 PF07690.11 EAQ93019.1 - 1.1e-29 103.2 31.0 1.6e-29 102.7 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.12 EAQ93023.1 - 2.2e-106 355.0 0.0 2.9e-106 354.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EAQ93023.1 - 7.2e-45 152.5 1.0 1.3e-44 151.6 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 EAQ93023.1 - 1.2e-38 132.6 0.0 2.9e-28 98.6 0.0 2.9 3 0 0 3 3 3 2 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 EAQ93023.1 - 1.7e-15 57.4 0.0 3.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Sugar_tr PF00083.19 EAQ93024.1 - 9.8e-94 314.4 21.1 1.1e-93 314.2 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ93024.1 - 5.4e-37 127.3 40.7 2.1e-32 112.1 15.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3881 PF12997.2 EAQ93024.1 - 0.13 11.2 0.1 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) Sugar_tr PF00083.19 EAQ93025.1 - 1.3e-71 241.4 15.7 1.7e-71 241.1 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ93025.1 - 2.9e-23 82.1 21.2 2.7e-19 69.0 6.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAQ93025.1 - 6.5e-05 21.5 15.4 0.00032 19.2 0.4 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 EAQ93025.1 - 0.00091 19.2 1.7 0.094 12.7 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) TRI12 PF06609.8 EAQ93025.1 - 0.012 13.8 2.1 0.018 13.2 1.5 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EAQ93026.1 - 3.7e-46 157.4 31.7 3.7e-46 157.4 22.0 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ93026.1 - 2.5e-13 49.4 9.0 2.5e-13 49.4 6.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EAQ93026.1 - 9.5e-05 20.7 7.7 0.00015 20.1 5.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 EAQ93026.1 - 3.4 8.1 5.1 6.7 7.1 0.1 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNase_PH PF01138.16 EAQ93029.1 - 4.9e-37 127.1 0.0 7.2e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAQ93029.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Thioredoxin PF00085.15 EAQ93030.1 - 9.4e-08 31.6 0.1 0.0006 19.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EAQ93030.1 - 1.5e-05 24.9 0.0 0.00021 21.1 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain ERp29_N PF07912.8 EAQ93030.1 - 0.0085 16.0 0.1 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain FAIM1 PF06905.8 EAQ93030.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Thioredoxin_2 PF13098.1 EAQ93030.1 - 0.12 12.6 0.5 1.2 9.4 0.1 2.7 1 1 1 2 2 2 0 Thioredoxin-like domain DUF605 PF04652.11 EAQ93031.1 - 1.4e-95 320.9 10.6 1.8e-95 320.5 7.4 1.1 1 0 0 1 1 1 1 Vta1 like Ax_dynein_light PF10211.4 EAQ93031.1 - 0.068 13.0 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain SDH_beta PF03315.10 EAQ93031.1 - 0.078 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Serine dehydratase beta chain FKBP_N PF01346.13 EAQ93031.1 - 0.18 11.8 2.2 0.26 11.3 0.8 1.7 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Acyl-CoA_dh_1 PF00441.19 EAQ93033.1 - 6.5e-20 71.7 4.2 6.5e-20 71.7 2.9 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAQ93033.1 - 4.1e-11 42.2 0.1 1.3e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EAQ93033.1 - 1.4e-10 41.7 0.4 5.7e-10 39.7 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAQ93033.1 - 5.6e-05 23.4 2.4 5.6e-05 23.4 1.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Neur_chan_memb PF02932.11 EAQ93034.1 - 0.18 11.6 3.4 0.29 10.9 2.1 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region JAB PF01398.16 EAQ93035.1 - 9e-30 102.7 0.2 2.5e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAQ93035.1 - 2.5e-26 91.9 0.6 4.4e-26 91.2 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EAQ93035.1 - 3.8e-08 32.8 0.0 7.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EAQ93036.1 - 2e-76 257.2 0.0 3.7e-76 256.4 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Peptidase_A4 PF01828.12 EAQ93037.1 - 5.4e-71 237.9 3.9 6.2e-71 237.7 2.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family DUF1212 PF06738.7 EAQ93038.1 - 1.5e-52 177.9 1.2 5e-50 169.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EAQ93038.1 - 5.6e-20 71.6 27.5 1.4e-10 41.2 1.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EAQ93038.1 - 0.067 13.3 5.5 0.028 14.6 1.9 1.7 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Amidoligase_2 PF12224.3 EAQ93039.1 - 5.8e-14 52.3 0.1 8.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Sigma70_ner PF04546.8 EAQ93040.1 - 0.021 14.4 1.9 0.029 13.9 1.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PhoU PF01895.14 EAQ93040.1 - 0.043 14.2 0.8 5.3 7.5 0.0 2.2 2 0 0 2 2 2 0 PhoU domain Nucleoplasmin PF03066.10 EAQ93040.1 - 0.26 10.7 4.7 0.36 10.3 3.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin AA_permease PF00324.16 EAQ93042.1 - 4.9e-119 397.7 48.4 6e-119 397.4 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAQ93042.1 - 1.8e-26 92.7 52.6 2.4e-26 92.2 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease Ribonuc_L-PSP PF01042.16 EAQ93044.1 - 9e-19 67.4 0.1 1.4e-18 66.8 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.17 EAQ93045.1 - 1.5e-142 475.2 0.0 1.7e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.1 EAQ93045.1 - 0.0077 15.8 1.7 0.031 13.9 0.1 2.6 2 1 1 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated Amidohydro_2 PF04909.9 EAQ93046.1 - 7.6e-43 147.0 0.5 1.1e-42 146.5 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase Ank_2 PF12796.2 EAQ93047.1 - 2.4e-27 95.0 0.0 3.3e-15 56.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ93047.1 - 3.1e-24 84.4 0.0 1.5e-10 40.9 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ93047.1 - 5.8e-23 79.4 0.9 2.7e-06 26.9 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EAQ93047.1 - 3.4e-20 71.9 0.1 4.4e-08 33.4 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ93047.1 - 2.5e-19 67.4 0.0 9.5e-05 22.2 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat zf-C2H2_4 PF13894.1 EAQ93047.1 - 2.9 8.4 28.0 0.12 12.8 0.4 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EAQ93047.1 - 5.9 6.6 9.6 0.66 9.7 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Amidohydro_3 PF07969.6 EAQ93049.1 - 4e-34 118.5 5.6 5.8e-34 117.9 3.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EAQ93049.1 - 5.5e-08 32.5 0.0 1.8e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EAQ93049.1 - 0.0007 19.7 4.3 0.0013 18.8 1.7 2.2 1 1 1 2 2 2 1 Amidohydrolase AP_endonuc_2 PF01261.19 EAQ93049.1 - 0.003 16.8 0.3 0.005 16.1 0.2 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 2OG-FeII_Oxy_3 PF13640.1 EAQ93050.1 - 0.019 15.4 0.1 0.043 14.3 0.1 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAQ93050.1 - 0.056 13.7 0.1 0.67 10.2 0.0 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily GBV-C_env PF12786.2 EAQ93050.1 - 0.057 11.8 0.0 0.092 11.1 0.0 1.3 1 0 0 1 1 1 0 GB virus C genotype envelope adh_short_C2 PF13561.1 EAQ93051.1 - 5.8e-15 55.7 0.0 5.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ93051.1 - 1e-12 48.3 1.2 2e-12 47.3 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ93051.1 - 7e-08 32.3 0.7 1.5e-07 31.2 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ93051.1 - 1.5e-06 27.8 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAQ93051.1 - 0.00034 19.4 0.0 0.00046 18.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EAQ93051.1 - 0.0057 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 EAQ93051.1 - 0.11 11.4 0.3 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pkinase PF00069.20 EAQ93052.1 - 2.9e-72 242.9 0.0 4.4e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93052.1 - 2.3e-36 125.1 0.0 4.5e-36 124.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ93052.1 - 0.00056 18.9 0.1 0.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EAQ93052.1 - 0.02 14.6 0.0 0.083 12.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.9 EAQ93052.1 - 0.85 7.5 4.5 1.7 6.6 3.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S28 PF05577.7 EAQ93053.1 - 6.8e-41 140.2 0.9 1.8e-33 115.7 0.2 2.1 1 1 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EAQ93053.1 - 0.00034 20.5 0.8 0.00082 19.3 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family PAP2 PF01569.16 EAQ93054.1 - 2.4e-13 49.8 0.2 4.6e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily AMP-binding PF00501.23 EAQ93055.1 - 4.7e-78 262.4 0.1 2.2e-77 260.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EAQ93055.1 - 2.2e-68 229.8 0.0 3.3e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAQ93055.1 - 1.1e-12 47.9 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EAQ93055.1 - 1.3e-10 41.3 0.0 2.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAQ93055.1 - 6.2e-09 36.6 0.0 2.3e-07 31.6 0.0 3.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EAQ93055.1 - 1.2e-08 33.9 0.0 2.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAQ93055.1 - 0.00051 19.9 2.6 0.00086 19.2 0.5 2.4 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAQ93055.1 - 0.021 13.6 0.0 1 8.1 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAQ93055.1 - 0.038 12.8 0.0 0.077 11.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EAQ93055.1 - 0.066 13.2 1.7 1.8 8.5 0.2 3.3 2 1 1 3 3 3 0 NADH(P)-binding SUR7 PF06687.7 EAQ93057.1 - 1.1e-12 47.9 0.1 1.5e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF3767 PF12597.3 EAQ93057.1 - 0.1 12.2 1.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) SET PF00856.23 EAQ93058.1 - 7.9e-13 49.0 0.0 2.2e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EAQ93058.1 - 0.03 14.7 0.1 7.9 6.9 0.0 2.4 2 0 0 2 2 2 0 SAF domain Amidoligase_2 PF12224.3 EAQ93060.1 - 5.4e-13 49.1 0.6 2.5e-12 46.9 0.1 2.3 1 1 0 2 2 2 1 Putative amidoligase enzyme SET PF00856.23 EAQ93061.1 - 3.7e-12 46.8 0.0 4.4e-11 43.3 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EAQ93061.1 - 3.7e-11 42.5 4.9 7.1e-05 22.3 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAQ93061.1 - 9.8e-09 34.4 1.4 6.7e-05 22.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ93061.1 - 0.00016 21.1 1.2 0.018 14.6 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ93061.1 - 0.00087 19.1 0.9 0.016 15.1 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ93061.1 - 0.0045 17.5 0.3 6.1 7.7 0.0 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ93061.1 - 0.65 10.7 4.8 0.84 10.3 0.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.7 EAQ93062.1 - 7.8e-08 32.1 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAQ93062.1 - 5.4e-07 29.8 0.0 3.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Acetyltransf_10 PF13673.1 EAQ93062.1 - 5.4e-05 23.2 0.1 0.0012 18.9 0.0 2.9 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain UPF0079 PF02367.12 EAQ93062.1 - 0.00012 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Acetyltransf_1 PF00583.19 EAQ93062.1 - 0.00076 19.4 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_33 PF13671.1 EAQ93062.1 - 0.0014 18.4 0.0 0.0071 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.1 EAQ93062.1 - 0.005 16.9 0.0 0.014 15.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_16 PF13191.1 EAQ93062.1 - 0.0083 16.1 0.0 0.095 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAQ93062.1 - 0.012 16.4 0.0 0.04 14.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAQ93062.1 - 0.02 13.7 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mitovir_RNA_pol PF05919.6 EAQ93062.1 - 0.027 13.4 0.0 0.053 12.4 0.0 1.4 2 0 0 2 2 2 0 Mitovirus RNA-dependent RNA polymerase DUF2075 PF09848.4 EAQ93062.1 - 0.042 12.8 0.0 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ank_4 PF13637.1 EAQ93062.1 - 0.073 13.6 0.0 0.49 10.9 0.0 2.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNA_helicase PF00910.17 EAQ93062.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase LuxE PF04443.7 EAQ93062.1 - 0.17 10.5 0.0 0.58 8.7 0.0 1.7 2 0 0 2 2 2 0 Acyl-protein synthetase, LuxE KaiC PF06745.8 EAQ93062.1 - 0.27 10.3 0.1 8.8 5.3 0.0 2.3 2 0 0 2 2 2 0 KaiC Hemerythrin PF01814.18 EAQ93063.1 - 4.8e-10 39.7 0.2 6.9e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fungal_trans_2 PF11951.3 EAQ93064.1 - 2.9e-52 177.5 1.5 4.1e-52 177.0 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ93064.1 - 4.1e-08 32.9 5.3 9.1e-08 31.8 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.18 EAQ93065.1 - 0.0023 17.7 14.3 0.0036 17.1 9.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain ENTH PF01417.15 EAQ93066.1 - 4.6e-48 162.2 0.1 6.8e-48 161.6 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EAQ93066.1 - 0.00017 20.3 0.1 0.00023 19.9 0.1 1.1 1 0 0 1 1 1 1 ANTH domain Pro_isomerase PF00160.16 EAQ93067.1 - 4.3e-14 52.9 0.2 5.2e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.7 EAQ93068.1 - 4.8e-129 430.2 0.0 5.9e-129 429.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EAQ93068.1 - 7.4e-05 23.1 0.5 0.012 15.9 0.0 3.1 2 1 0 2 2 2 1 Replication protein A C terminal HTH_34 PF13601.1 EAQ93068.1 - 0.0058 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain B-block_TFIIIC PF04182.7 EAQ93068.1 - 0.013 15.3 0.1 0.51 10.2 0.0 2.9 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC HTH_36 PF13730.1 EAQ93068.1 - 0.024 14.7 0.0 0.088 12.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.17 EAQ93068.1 - 0.024 14.3 0.0 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 MarR family TrmB PF01978.14 EAQ93068.1 - 0.047 13.3 0.2 15 5.3 0.0 2.7 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 EAQ93068.1 - 0.07 13.2 0.0 9.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator MFS_1 PF07690.11 EAQ93069.1 - 5.4e-31 107.5 28.4 9.1e-31 106.8 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.4 EAQ93070.1 - 2.7e-17 63.0 1.9 2.7e-17 63.0 1.3 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.17 EAQ93071.1 - 1.9e-46 158.5 0.0 6.3e-39 133.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TPR_11 PF13414.1 EAQ93074.1 - 7.6e-57 188.8 28.9 3.1e-16 58.7 1.1 6.7 7 0 0 7 7 7 6 TPR repeat TPR_1 PF00515.23 EAQ93074.1 - 2.9e-38 127.9 28.3 1.8e-06 27.3 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ93074.1 - 1e-30 103.1 33.1 0.00017 21.2 0.0 10.2 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EAQ93074.1 - 5.7e-18 64.6 14.1 2.1e-10 40.3 0.9 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ93074.1 - 3.7e-15 56.1 18.5 0.0013 19.3 0.2 6.9 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ93074.1 - 1.9e-14 52.2 8.7 0.0016 18.0 0.0 8.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ93074.1 - 2e-14 52.7 9.8 0.048 14.3 0.0 8.7 7 3 4 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ93074.1 - 4.9e-11 41.9 9.6 0.69 10.2 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ93074.1 - 1.2e-10 40.3 19.7 0.009 15.7 0.2 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ93074.1 - 1.9e-09 37.7 10.8 0.0083 16.4 0.0 6.6 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAQ93074.1 - 2.5e-08 33.6 1.3 0.047 13.5 0.0 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EAQ93074.1 - 1.1e-05 25.5 8.8 0.0014 18.7 2.2 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EAQ93074.1 - 0.00043 20.1 0.9 0.89 9.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ93074.1 - 0.0074 16.6 17.5 0.089 13.2 0.1 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAQ93074.1 - 0.32 10.9 5.4 7.5 6.5 0.1 4.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Gastrin PF00918.12 EAQ93074.1 - 2.5 8.9 5.9 2.2 9.1 0.2 3.1 3 0 0 3 3 3 0 Gastrin/cholecystokinin family DUF357 PF04010.8 EAQ93074.1 - 7.1 6.4 8.4 2.4 7.9 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF357) HMG-CoA_red PF00368.13 EAQ93075.1 - 2.2e-119 398.4 4.1 2.4e-119 398.3 2.8 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase MFS_1 PF07690.11 EAQ93076.1 - 2e-40 138.5 59.6 2e-40 138.5 41.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ93076.1 - 2.9e-15 55.8 12.3 2.9e-15 55.8 8.5 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EAQ93076.1 - 7.5e-14 50.8 25.8 1e-13 50.4 17.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Esterase_phd PF10503.4 EAQ93077.1 - 9e-26 90.4 0.7 1.3e-25 89.9 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EAQ93077.1 - 2.2e-13 49.9 1.1 3.8e-13 49.1 0.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.13 EAQ93077.1 - 1e-11 44.2 13.1 1e-11 44.2 9.1 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 EAQ93077.1 - 6.4e-08 32.4 0.1 8.9e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ93077.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EAQ93077.1 - 0.00032 20.2 0.3 0.0005 19.5 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EAQ93077.1 - 0.00087 18.9 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EAQ93077.1 - 0.0038 15.9 0.1 0.0066 15.2 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 EAQ93077.1 - 0.016 14.8 0.1 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Toxin_7 PF05980.7 EAQ93077.1 - 0.084 12.9 4.7 0.21 11.6 3.2 1.7 1 0 0 1 1 1 0 Toxin 7 Abhydrolase_2 PF02230.11 EAQ93077.1 - 0.089 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EAQ93077.1 - 0.14 11.8 0.2 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_3 PF00933.16 EAQ93078.1 - 7.7e-54 182.6 0.0 1.1e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAQ93078.1 - 2.6e-13 50.0 0.0 1.2e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain RRM_1 PF00076.17 EAQ93079.1 - 1.7e-20 72.4 0.0 2.8e-11 42.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93079.1 - 3.1e-17 62.3 0.0 1.4e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93079.1 - 1.5e-12 47.1 0.0 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOR PF05036.8 EAQ93079.1 - 0.0041 17.2 0.1 3.9 7.6 0.0 2.5 2 0 0 2 2 2 2 Sporulation related domain Limkain-b1 PF11608.3 EAQ93079.1 - 0.046 13.4 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM PF05172.8 EAQ93079.1 - 0.099 12.4 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif bZIP_1 PF00170.16 EAQ93080.1 - 0.00038 20.3 9.3 0.00057 19.7 6.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAQ93080.1 - 0.65 9.8 13.2 1.4 8.7 9.1 1.6 1 1 0 1 1 1 0 Basic region leucine zipper GFO_IDH_MocA PF01408.17 EAQ93081.1 - 1.1e-06 29.1 0.0 2.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold WSC PF01822.14 EAQ93082.1 - 7.5e-16 57.8 16.0 2.7e-11 43.2 2.7 3.4 3 0 0 3 3 3 2 WSC domain LysM PF01476.15 EAQ93082.1 - 0.0001 22.1 0.2 0.019 14.8 0.0 3.2 3 0 0 3 3 3 1 LysM domain Bowman-Birk_leg PF00228.15 EAQ93082.1 - 0.1 12.4 4.3 0.39 10.5 0.3 2.9 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family Chitin_bind_1 PF00187.14 EAQ93083.1 - 2.1e-09 37.1 28.0 4.7e-05 23.2 2.1 2.5 2 0 0 2 2 2 2 Chitin recognition protein F-box-like PF12937.2 EAQ93084.1 - 0.0026 17.4 1.5 0.0035 17.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like RVT_1 PF00078.22 EAQ93086.1 - 4.2e-32 111.2 0.0 8.4e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EAQ93086.1 - 9.4e-21 73.6 0.0 1.2e-19 70.0 0.0 2.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EAQ93086.1 - 1.2e-07 31.9 0.1 2.3e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SlyX PF04102.7 EAQ93086.1 - 0.012 15.9 4.6 0.17 12.2 2.4 2.8 1 1 1 2 2 2 0 SlyX CorA PF01544.13 EAQ93086.1 - 0.12 11.3 2.2 0.22 10.5 1.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4226 PF10774.4 EAQ93086.1 - 0.34 10.9 5.8 0.1 12.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Mnd1 PF03962.10 EAQ93086.1 - 0.41 10.2 2.4 0.87 9.2 1.7 1.4 1 0 0 1 1 1 0 Mnd1 family Pkinase PF00069.20 EAQ93087.1 - 2.1e-28 99.1 0.0 3.4e-28 98.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93087.1 - 3.9e-09 35.9 0.2 2.1e-07 30.2 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase DUF4509 PF14970.1 EAQ93087.1 - 0.041 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Pox_ser-thr_kin PF05445.6 EAQ93087.1 - 0.094 11.4 0.1 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_26 PF02156.10 EAQ93088.1 - 6.2e-89 298.5 3.3 8.5e-89 298.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 DUF1888 PF08985.6 EAQ93088.1 - 0.03 13.9 0.2 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1888) Sod_Cu PF00080.15 EAQ93089.1 - 2.9e-10 40.4 1.9 9.1e-09 35.5 0.2 2.2 1 1 1 2 2 2 2 Copper/zinc superoxide dismutase (SODC) p450 PF00067.17 EAQ93090.1 - 3.8e-26 91.6 0.0 5.5e-25 87.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 dTMP_synthase PF02593.9 EAQ93092.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase Ribosomal_L44 PF00935.14 EAQ93093.1 - 4e-35 119.6 11.4 5.9e-35 119.1 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EAQ93093.1 - 1.9 8.8 9.8 0.41 10.9 1.2 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 DUF3433 PF11915.3 EAQ93095.1 - 5.4e-18 64.9 3.3 5.4e-18 64.9 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) SPW PF03779.9 EAQ93095.1 - 0.81 9.1 4.3 0.38 10.1 0.6 2.2 2 0 0 2 2 2 0 SPW repeat Mito_fiss_reg PF05308.6 EAQ93096.1 - 0.015 14.6 0.8 0.018 14.4 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Pex14_N PF04695.8 EAQ93096.1 - 0.074 13.0 4.2 0.11 12.4 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.1 EAQ93096.1 - 0.21 11.7 1.1 0.27 11.3 0.8 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Menin PF05053.8 EAQ93096.1 - 4.3 5.3 5.1 5.2 5.1 3.5 1.1 1 0 0 1 1 1 0 Menin Chitin_bind_3 PF03067.10 EAQ93097.1 - 0.0003 21.1 0.2 0.0011 19.2 0.0 2.0 2 1 0 2 2 2 1 Chitin binding domain Daxx PF03344.10 EAQ93097.1 - 0.02 13.3 10.2 0.027 12.9 7.1 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EAQ93097.1 - 1.1 7.0 8.6 1.4 6.7 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EAQ93097.1 - 2.1 6.6 7.2 3.1 6.0 5.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.4 EAQ93097.1 - 2.7 6.6 10.8 3.8 6.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EAQ93097.1 - 4.1 6.5 8.4 5.6 6.1 5.8 1.1 1 0 0 1 1 1 0 SDA1 Herpes_Helicase PF02689.9 EAQ93098.1 - 0.00012 19.9 0.0 0.00017 19.5 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAQ93098.1 - 0.00071 19.6 0.0 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain RVT_1 PF00078.22 EAQ93099.1 - 0.0014 18.0 0.0 0.0031 16.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIF1 PF05970.9 EAQ93101.1 - 8.3e-19 67.7 0.0 1.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAQ93101.1 - 3.1e-06 26.9 0.2 8e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAQ93101.1 - 0.00044 20.3 0.0 0.0018 18.4 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MFS_1 PF07690.11 EAQ93102.1 - 3.9e-06 25.8 29.4 1.6e-05 23.8 18.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAQ93102.1 - 0.0024 17.6 1.3 0.009 15.7 0.1 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF3112 PF11309.3 EAQ93102.1 - 0.027 14.2 0.3 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Zn_clus PF00172.13 EAQ93103.1 - 4.8e-10 39.1 10.8 1.2e-09 37.9 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ93103.1 - 4.1e-05 22.5 0.1 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EAQ93104.1 - 1.3e-08 33.7 0.1 3.8e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EAQ93106.1 - 2.6e-24 85.6 50.3 2.4e-19 69.2 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferric_reduct PF01794.14 EAQ93107.1 - 4.5e-20 72.0 14.4 4.5e-20 72.0 10.0 2.8 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EAQ93107.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Methyltransf_18 PF12847.2 EAQ93108.1 - 1.4e-10 41.6 0.0 2.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ93108.1 - 5.7e-10 38.9 0.0 7.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ93108.1 - 2.6e-08 33.2 0.0 3.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EAQ93108.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ93108.1 - 1.9e-07 31.4 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ93108.1 - 2e-07 31.4 0.0 3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ93108.1 - 2.6e-07 30.6 0.1 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAQ93108.1 - 8.8e-06 25.0 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EAQ93108.1 - 0.00014 21.3 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EAQ93108.1 - 0.00033 20.4 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAQ93108.1 - 0.00088 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.6 EAQ93108.1 - 0.069 11.8 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_6 PF03737.10 EAQ93109.1 - 1.4e-18 67.1 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase MFS_1 PF07690.11 EAQ93111.1 - 1.6e-22 79.6 59.3 4.8e-15 55.1 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavodoxin_1 PF00258.20 EAQ93112.1 - 2.1e-10 40.7 0.0 4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EAQ93112.1 - 1.1e-07 31.5 0.0 1.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EAQ93112.1 - 5.2e-07 29.3 0.0 7.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EAQ93112.1 - 0.053 12.8 0.1 0.23 10.7 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin Yae1_N PF09811.4 EAQ93113.1 - 1.5e-10 40.4 4.3 3.4e-10 39.2 3.0 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 EAQ93113.1 - 0.54 10.4 2.8 0.29 11.3 0.3 1.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Ribosomal_S8 PF00410.14 EAQ93115.1 - 6.5e-28 97.1 0.0 8.2e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 SPO11_like PF03533.9 EAQ93115.1 - 0.017 14.9 0.2 0.042 13.7 0.2 1.7 1 0 0 1 1 1 0 SPO11 homologue Iso_dh PF00180.15 EAQ93118.1 - 3.2e-96 322.2 0.0 4.5e-96 321.8 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.6 EAQ93118.1 - 0.074 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) GTP_EFTU PF00009.22 EAQ93119.1 - 5.4e-56 188.9 0.0 1.5e-55 187.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EAQ93119.1 - 1.2e-32 111.5 0.0 2.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EAQ93119.1 - 5.4e-31 106.6 0.0 1.3e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EAQ93119.1 - 3.9e-22 77.9 0.0 8.7e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EAQ93119.1 - 8.4e-14 51.4 0.0 2e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EAQ93119.1 - 0.056 13.3 0.1 2.9 7.7 0.0 3.0 3 0 0 3 3 3 0 Putative phosphatase (DUF442) Asp PF00026.18 EAQ93120.1 - 5.4e-64 216.4 0.5 6.8e-64 216.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ93120.1 - 2.9e-06 27.3 0.1 3.7e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ93120.1 - 0.0023 18.3 0.1 0.36 11.3 0.1 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EAQ93120.1 - 0.0045 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EAQ93120.1 - 0.063 13.1 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PDZ_1 PF12812.2 EAQ93120.1 - 0.13 12.2 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 PDZ-like domain Aminotran_1_2 PF00155.16 EAQ93122.1 - 1.9e-36 125.8 0.0 2.4e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EAQ93122.1 - 1.1e-05 24.3 0.0 2.4e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EAQ93122.1 - 1.7e-05 23.2 0.0 2.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EAQ93122.1 - 2.2e-05 23.7 0.0 4.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 EAQ93122.1 - 0.0088 14.6 0.0 0.012 14.1 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 EAQ93122.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Allinase ABC2_membrane PF01061.19 EAQ93123.1 - 1.5e-37 128.8 22.6 2.8e-37 127.9 15.7 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EAQ93123.1 - 1.7e-24 86.6 0.0 3.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAQ93123.1 - 3e-09 37.2 0.0 4.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EAQ93123.1 - 2.8e-08 33.1 25.3 2.8e-08 33.1 17.5 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EAQ93123.1 - 5e-05 22.7 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EAQ93123.1 - 0.0012 17.9 0.0 0.66 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EAQ93123.1 - 0.0063 16.0 0.1 0.015 14.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EAQ93123.1 - 0.011 14.9 0.1 0.031 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 hEGF PF12661.2 EAQ93123.1 - 0.012 15.6 8.4 0.028 14.5 1.7 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF SMC_N PF02463.14 EAQ93123.1 - 0.019 14.1 0.0 0.39 9.9 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EAQ93123.1 - 0.025 14.8 0.0 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EAQ93123.1 - 0.032 14.3 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAQ93123.1 - 0.055 13.7 0.2 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 EAQ93123.1 - 0.058 12.2 22.3 42 2.8 15.5 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein NACHT PF05729.7 EAQ93123.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EAQ93123.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EAQ93123.1 - 0.092 12.6 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EAQ93123.1 - 0.096 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EAQ93123.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EAQ93123.1 - 0.11 13.2 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAQ93123.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DHH PF01368.15 EAQ93124.1 - 0.059 13.0 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 DHH family SPT16 PF08644.6 EAQ93124.1 - 0.14 11.9 1.5 0.93 9.3 0.1 2.2 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF1476 PF07345.6 EAQ93124.1 - 0.84 9.9 7.3 0.057 13.6 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) NGP1NT PF08153.7 EAQ93125.1 - 1.9e-48 163.6 0.6 2.8e-48 163.1 0.4 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EAQ93125.1 - 4.2e-17 62.1 0.0 9.2e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAQ93125.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EAQ93125.1 - 0.00018 20.7 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAQ93125.1 - 0.0012 18.7 0.1 0.15 11.8 0.0 2.8 1 1 1 2 2 2 1 Dynamin family BUD22 PF09073.5 EAQ93125.1 - 4.3 6.3 21.9 9 5.2 15.2 1.5 1 0 0 1 1 1 0 BUD22 APT PF03440.9 EAQ93126.1 - 0.05 13.3 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Thioredoxin_4 PF13462.1 EAQ93128.1 - 4.5e-05 23.5 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAQ93128.1 - 0.038 14.1 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.15 EAQ93128.1 - 0.056 12.9 2.4 3.1 7.3 0.2 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EAQ93128.1 - 0.064 13.0 0.1 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF1713 PF08213.6 EAQ93129.1 - 1.4e-11 43.7 22.2 1.4e-11 43.7 15.4 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) EF_assoc_1 PF08355.7 EAQ93129.1 - 0.18 11.1 0.7 0.37 10.1 0.5 1.5 1 0 0 1 1 1 0 EF hand associated Rabaptin PF03528.10 EAQ93129.1 - 0.29 11.0 0.0 0.29 11.0 0.0 2.8 3 1 0 3 3 3 0 Rabaptin ER-remodelling PF14755.1 EAQ93129.1 - 1.6 8.8 11.1 0.92 9.5 3.9 2.6 2 1 0 2 2 2 0 Intracellular membrane remodeller Raffinose_syn PF05691.7 EAQ93130.1 - 1.6e-48 164.8 0.4 8.3e-40 136.0 0.0 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EAQ93130.1 - 0.00028 19.7 0.5 0.0006 18.6 0.3 1.4 1 1 0 1 1 1 1 Melibiase AIRC PF00731.15 EAQ93131.1 - 2e-58 195.9 2.2 5e-58 194.6 1.5 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EAQ93131.1 - 7e-36 123.1 0.0 9.8e-35 119.4 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EAQ93131.1 - 0.00014 21.6 0.0 0.00041 20.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain XdhC_C PF13478.1 EAQ93131.1 - 0.00035 20.9 0.2 0.22 11.8 0.0 2.8 3 0 0 3 3 3 2 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EAQ93131.1 - 0.0019 17.4 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 EAQ93131.1 - 0.0066 15.8 0.8 0.066 12.6 0.0 2.5 2 0 0 2 2 2 1 Propionate catabolism activator CPSase_L_D2 PF02786.12 EAQ93131.1 - 0.02 14.1 1.1 1.3 8.2 0.0 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_M16 PF00675.15 EAQ93132.1 - 3.8e-57 192.2 1.0 6.8e-57 191.4 0.3 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAQ93132.1 - 3.5e-38 131.1 0.0 1.1e-37 129.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Esterase PF00756.15 EAQ93132.1 - 0.037 13.4 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase zf-RING_2 PF13639.1 EAQ93134.1 - 6.1e-14 51.5 6.3 9.4e-14 50.9 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAQ93134.1 - 2.1e-08 34.1 4.5 4.2e-08 33.1 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAQ93134.1 - 7e-08 31.9 4.0 1.1e-07 31.3 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ93134.1 - 1.3e-06 28.0 3.7 2e-06 27.4 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAQ93134.1 - 2.8e-05 24.0 5.1 4.7e-05 23.3 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ93134.1 - 6.4e-05 22.5 2.4 0.0001 21.8 1.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAQ93134.1 - 0.00059 19.6 2.7 0.0011 18.7 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EAQ93134.1 - 0.012 15.1 6.2 0.02 14.4 4.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EAQ93134.1 - 0.031 14.0 0.3 0.081 12.6 0.1 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAQ93134.1 - 0.064 13.1 4.3 0.13 12.1 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EAQ93134.1 - 0.14 11.8 5.5 0.24 11.1 3.8 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EAQ93134.1 - 0.25 11.3 3.1 0.68 9.9 2.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EAQ93134.1 - 0.45 10.5 5.5 0.87 9.6 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EAQ93134.1 - 2.4 7.9 8.0 0.2 11.4 1.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.3 EAQ93135.1 - 7.4e-44 149.5 5.0 1.4e-43 148.5 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Vps8 PF12816.2 EAQ93136.1 - 3.9e-76 254.6 0.0 6.8e-76 253.8 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.7 EAQ93136.1 - 6.9e-44 148.5 0.0 1.5e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.15 EAQ93136.1 - 6.2e-05 22.6 0.0 0.049 13.2 0.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF605 PF04652.11 EAQ93136.1 - 0.056 12.8 6.3 0.12 11.7 4.3 1.5 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 EAQ93136.1 - 1.3 7.0 12.3 0.0054 14.8 2.2 1.5 2 0 0 2 2 2 0 CDC45-like protein SSP160 PF06933.6 EAQ93136.1 - 1.7 6.4 11.3 2.7 5.8 7.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Actin PF00022.14 EAQ93138.1 - 1.7e-139 464.6 0.0 1.9e-139 464.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAQ93138.1 - 3.1e-05 22.7 0.1 0.0059 15.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EAQ93138.1 - 0.14 11.2 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase D-ser_dehydrat PF14031.1 EAQ93139.1 - 3.1e-23 81.7 0.0 5.8e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EAQ93139.1 - 1.7e-07 31.0 0.0 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3591 PF12157.3 EAQ93140.1 - 1e-185 617.5 0.0 1.6e-185 616.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.18 EAQ93140.1 - 0.13 12.2 0.5 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle SRF-TF PF00319.13 EAQ93143.1 - 1.4e-22 78.6 0.1 2.2e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FRG1 PF06229.7 EAQ93144.1 - 1.4e-55 187.7 0.0 1.7e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EAQ93144.1 - 0.036 14.1 0.0 0.089 12.8 0.0 1.8 2 0 0 2 2 2 0 Fascin domain 2OG-FeII_Oxy PF03171.15 EAQ93145.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4448 PF14610.1 EAQ93146.1 - 2.2e-45 154.4 0.0 2.7e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Glyco_hydro_31 PF01055.21 EAQ93147.1 - 1.7e-101 340.2 6.7 1.4e-100 337.2 4.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.19 EAQ93148.1 - 1.3e-122 409.6 23.3 1.5e-122 409.4 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ93148.1 - 1e-21 77.0 37.4 4.5e-17 61.7 10.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Hamartin PF04388.7 EAQ93148.1 - 0.3 9.6 0.8 0.43 9.2 0.6 1.1 1 0 0 1 1 1 0 Hamartin protein FAD_binding_2 PF00890.19 EAQ93149.1 - 4.5e-85 286.0 0.7 5.6e-85 285.7 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EAQ93149.1 - 2e-21 75.5 0.6 6.1e-20 70.8 0.0 3.2 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EAQ93149.1 - 2e-12 46.7 2.7 1.1e-11 44.2 1.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EAQ93149.1 - 3.7e-10 39.4 0.4 1.4e-09 37.5 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ93149.1 - 9.1e-09 35.2 3.8 4.9e-08 32.8 0.4 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAQ93149.1 - 2.4e-08 34.1 0.0 1.6e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAQ93149.1 - 4.8e-06 25.3 2.6 0.0053 15.2 0.1 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EAQ93149.1 - 2.5e-05 23.4 1.2 0.0086 15.2 0.2 2.6 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.19 EAQ93149.1 - 0.0046 16.0 0.2 0.16 10.9 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EAQ93149.1 - 0.0068 15.3 4.6 0.13 11.1 0.9 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EAQ93149.1 - 0.0079 15.2 2.8 0.015 14.3 1.9 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAQ93149.1 - 0.04 13.9 1.3 0.11 12.5 0.9 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ93149.1 - 1.4 9.3 3.9 3.1 8.2 1.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAH PF02671.16 EAQ93150.1 - 3.4e-41 138.6 1.3 2.1e-17 62.4 0.6 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EAQ93150.1 - 4.9e-39 132.1 0.8 1.2e-38 130.9 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Fasciclin PF02469.17 EAQ93150.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Fasciclin domain Chromate_transp PF02417.10 EAQ93151.1 - 4e-15 55.8 13.4 2e-14 53.5 9.3 1.9 1 1 0 1 1 1 1 Chromate transporter CcmH PF03918.9 EAQ93151.1 - 4 6.4 4.8 2 7.4 0.4 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Fungal_trans PF04082.13 EAQ93152.1 - 0.00079 18.3 0.1 0.0029 16.5 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF59 PF01883.14 EAQ93153.1 - 2.1e-05 24.4 0.0 5.8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 EAQ93154.1 - 8.5e-43 145.9 0.0 1.2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAQ93154.1 - 1.7e-18 66.2 0.0 4.7e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EAQ93154.1 - 2.4e-17 62.6 0.0 6.7e-17 61.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EAQ93154.1 - 1.4e-09 37.8 0.3 4.2e-09 36.3 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EAQ93154.1 - 7.8e-07 28.8 0.0 1.7e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EAQ93154.1 - 2.8e-06 27.2 0.1 5.4e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAQ93154.1 - 0.0018 18.7 0.0 0.0062 17.0 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Thiolase_N PF00108.18 EAQ93155.1 - 1.7e-94 315.6 0.5 1.7e-94 315.6 0.3 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAQ93155.1 - 5.2e-47 158.3 0.3 1.2e-46 157.0 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EAQ93155.1 - 4.6e-05 23.0 0.6 4.6e-05 23.0 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EAQ93155.1 - 0.022 14.4 3.6 0.22 11.1 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sel1 PF08238.7 EAQ93156.1 - 1.6e-41 139.8 55.9 3.3e-06 27.5 0.9 13.4 13 1 1 14 14 14 10 Sel1 repeat Fer2_3 PF13085.1 EAQ93157.1 - 2.4e-33 114.2 0.0 3.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 EAQ93157.1 - 0.0014 18.3 0.2 0.0028 17.3 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 EAQ93157.1 - 0.071 13.5 0.4 0.071 13.5 0.2 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding DUF3348 PF11828.3 EAQ93157.1 - 0.11 11.9 1.3 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) WD40 PF00400.27 EAQ93161.1 - 3.3e-50 166.2 21.1 7.6e-10 38.2 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat PRP4 PF08799.6 EAQ93161.1 - 2.1e-15 55.6 2.1 3.4e-15 54.9 1.4 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EAQ93161.1 - 0.0048 16.6 0.0 0.86 9.2 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EAQ93161.1 - 0.1 11.3 0.3 4.1 6.0 0.2 2.2 1 1 0 1 1 1 0 Nup133 N terminal like Ribosomal_60s PF00428.14 EAQ93161.1 - 0.22 11.9 4.1 0.53 10.7 2.8 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 EAQ93162.1 - 7e-67 225.3 0.0 8.7e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93162.1 - 2.8e-29 101.9 0.0 3.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EAQ93162.1 - 0.0018 18.7 0.0 0.005 17.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAQ93162.1 - 0.0041 16.1 0.1 0.012 14.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EAQ93162.1 - 0.034 13.8 0.3 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family ATP_sub_h PF10775.4 EAQ93163.1 - 4.2e-25 87.2 0.7 6.3e-25 86.6 0.5 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EAQ93163.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Pkinase PF00069.20 EAQ93164.1 - 6.4e-71 238.5 0.0 8.7e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93164.1 - 3e-31 108.4 0.0 4.3e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EAQ93164.1 - 1.9e-14 53.8 1.4 5e-14 52.5 1.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAQ93164.1 - 1.2e-09 37.5 0.0 2.3e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EAQ93164.1 - 0.00014 21.6 0.0 0.00045 20.0 0.0 1.9 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 EAQ93164.1 - 0.01 14.8 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EAQ93164.1 - 0.033 13.5 0.1 0.081 12.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 EAQ93164.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ93164.1 - 0.056 13.0 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUZ PF12752.2 EAQ93167.1 - 8.5e-07 29.3 6.6 2.6e-06 27.8 1.3 2.7 2 0 0 2 2 2 1 SUZ domain U1snRNP70_N PF12220.3 EAQ93167.1 - 0.11 12.7 8.5 0.052 13.8 1.7 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rrn6 PF10214.4 EAQ93167.1 - 4.7 5.1 7.2 0.32 9.0 1.7 1.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor YqfQ PF14181.1 EAQ93167.1 - 6.7 6.7 8.3 1.9 8.5 2.6 2.0 2 0 0 2 2 2 0 YqfQ-like protein Fe_hyd_lg_C PF02906.9 EAQ93168.1 - 7.5e-61 205.8 0.0 1.8e-60 204.6 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.1 EAQ93170.1 - 1.2e-07 31.6 2.4 2.9e-06 27.3 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EAQ93170.1 - 2.9e-06 27.3 1.8 0.00015 21.8 0.2 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAQ93170.1 - 0.0001 22.3 3.3 0.00049 20.2 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAQ93170.1 - 1 9.5 5.2 3.7 7.7 0.4 2.9 2 2 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LRR_6 PF13516.1 EAQ93171.1 - 9.1e-11 40.6 16.0 0.028 14.4 0.0 7.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EAQ93171.1 - 2.9e-08 33.1 17.0 0.0014 18.1 0.0 5.7 4 3 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EAQ93171.1 - 8.4e-07 28.1 4.2 5.1 7.5 0.0 6.2 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 EAQ93171.1 - 0.0021 17.7 15.4 0.35 10.6 0.0 4.9 3 3 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EAQ93171.1 - 0.007 16.3 7.9 22 5.8 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat LETM1 PF07766.8 EAQ93171.1 - 0.33 9.9 0.0 0.33 9.9 0.0 2.7 3 0 0 3 3 3 0 LETM1-like protein Myc_N PF01056.13 EAQ93171.1 - 0.37 9.9 8.3 0.54 9.3 5.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Glyco_hydro_18 PF00704.23 EAQ93172.1 - 1e-80 271.7 0.1 1.3e-80 271.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cmc1 PF08583.5 EAQ93174.1 - 0.0085 15.8 3.5 0.0085 15.8 2.5 2.2 2 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like HWE_HK PF07536.9 EAQ93174.1 - 0.084 13.3 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 HWE histidine kinase CHCH PF06747.8 EAQ93174.1 - 0.55 10.2 4.6 7.3 6.6 0.3 2.4 2 0 0 2 2 2 0 CHCH domain AflR PF08493.5 EAQ93174.1 - 3 6.7 5.1 43 2.9 3.3 2.2 2 0 0 2 2 2 0 Aflatoxin regulatory protein Ank_2 PF12796.2 EAQ93176.1 - 2.4e-39 133.5 11.0 2e-11 44.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAQ93176.1 - 2.9e-28 97.7 10.9 4.8e-08 33.3 0.5 6.7 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.25 EAQ93176.1 - 3.7e-27 92.7 21.3 4.6e-06 26.1 0.1 8.0 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EAQ93176.1 - 2.9e-25 87.6 15.5 1.5e-10 40.9 0.3 5.9 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ93176.1 - 1.8e-19 67.8 8.3 0.0031 17.6 0.1 7.5 7 1 0 7 7 7 5 Ankyrin repeat PmrD PF11183.3 EAQ93176.1 - 0.029 14.1 0.0 0.099 12.4 0.0 1.9 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD TIP120 PF08623.5 EAQ93177.1 - 0.042 13.4 2.9 0.092 12.3 2.0 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) CutA1 PF03091.10 EAQ93177.1 - 0.051 13.2 0.3 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein DUF3538 PF12057.3 EAQ93177.1 - 0.06 12.9 2.8 1 8.9 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3538) DUF530 PF04409.7 EAQ93177.1 - 0.063 11.3 0.7 0.089 10.8 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF530) DUF342 PF03961.8 EAQ93177.1 - 0.28 9.5 3.0 0.39 9.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FH2 PF02181.18 EAQ93177.1 - 0.45 9.3 6.1 0.88 8.3 4.2 1.8 1 1 0 1 1 1 0 Formin Homology 2 Domain FUSC PF04632.7 EAQ93177.1 - 1.1 7.5 8.7 1.9 6.8 6.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family COG5 PF10392.4 EAQ93177.1 - 1.2 9.0 10.4 0.36 10.7 3.2 2.6 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF1759 PF03564.10 EAQ93177.1 - 1.6 8.5 5.4 2.1 8.1 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) CDC37_N PF03234.9 EAQ93177.1 - 2.2 8.5 8.3 13 6.0 0.1 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Phasin_2 PF09361.5 EAQ93177.1 - 2.4 8.2 15.3 0.25 11.3 7.0 2.0 2 0 0 2 2 2 0 Phasin protein MutS_III PF05192.13 EAQ93177.1 - 2.6 7.7 6.2 6.5 6.4 4.3 1.9 1 1 0 1 1 1 0 MutS domain III CR6_interact PF10147.4 EAQ93177.1 - 3.7 6.8 8.9 0.5 9.6 1.2 2.0 1 1 2 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TPR_12 PF13424.1 EAQ93179.1 - 3.9e-37 126.0 12.6 7e-14 51.5 0.2 6.4 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ93179.1 - 3.1e-33 112.7 8.2 7.5e-09 35.2 0.1 8.4 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ93179.1 - 1.9e-09 36.5 7.5 0.08 12.7 0.1 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ93179.1 - 3e-07 29.9 4.9 0.061 12.9 0.0 4.9 5 3 1 6 6 6 3 TPR repeat TPR_14 PF13428.1 EAQ93179.1 - 1.1e-06 28.7 14.4 1.3 9.8 0.0 8.5 7 3 3 10 10 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ93179.1 - 1.4e-06 27.7 16.2 0.43 10.6 0.0 7.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ93179.1 - 1.5e-06 28.0 5.2 17 6.2 0.0 7.5 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ93179.1 - 7.3e-06 26.2 3.8 5.5 7.3 0.0 6.1 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ93179.1 - 2.4e-05 24.8 6.8 4.9 7.9 0.0 6.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAQ93179.1 - 2.8e-05 23.5 12.0 0.26 10.9 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ93179.1 - 7.9e-05 22.5 1.5 8.1 6.9 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EAQ93179.1 - 0.00014 21.8 1.7 5.9 7.1 0.2 3.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EAQ93179.1 - 0.012 15.3 4.0 5.9 6.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAQ93179.1 - 0.054 13.9 13.7 1.9 9.1 0.0 6.4 7 1 0 7 7 6 0 Tetratricopeptide repeat RVT_1 PF00078.22 EAQ93180.1 - 2e-30 105.7 0.0 3e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ER_lumen_recept PF00810.13 EAQ93181.1 - 3.6e-37 128.1 12.8 5.1e-37 127.6 8.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EAQ93181.1 - 0.023 14.2 0.2 0.023 14.2 0.1 3.2 4 0 0 4 4 4 0 PQ loop repeat Daxx PF03344.10 EAQ93182.1 - 4.6 5.5 17.5 10 4.4 12.1 1.5 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EAQ93182.1 - 5.8 4.6 14.9 9.3 4.0 10.3 1.2 1 0 0 1 1 1 0 Nop14-like family Proteasome PF00227.21 EAQ93183.1 - 2e-45 154.3 0.2 2.6e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EAQ93183.1 - 4.7e-13 48.1 0.0 9.7e-13 47.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Sel1 PF08238.7 EAQ93184.1 - 1.4e-15 57.3 6.4 0.00061 20.3 0.0 4.4 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.7 EAQ93185.1 - 3.3e-66 223.0 0.6 7.4e-43 146.7 0.3 2.2 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EAQ93185.1 - 2.2e-35 120.5 0.0 4.8e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Acetyltransf_3 PF13302.1 EAQ93186.1 - 4.1e-18 65.9 0.0 5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ93186.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Per1 PF04080.8 EAQ93187.1 - 3.9e-103 344.5 7.7 4.8e-103 344.2 5.3 1.1 1 0 0 1 1 1 1 Per1-like Ppx-GppA PF02541.11 EAQ93190.1 - 1.4e-24 86.7 0.0 3.5e-23 82.1 0.0 2.1 1 1 0 1 1 1 1 Ppx/GppA phosphatase family ATP-grasp PF02222.17 EAQ93191.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp domain Metallophos_2 PF12850.2 EAQ93194.1 - 1.6e-07 31.3 0.1 3.7e-07 30.1 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAQ93194.1 - 8.4e-07 28.5 0.1 1.3e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RCR PF12273.3 EAQ93195.1 - 6.9e-23 81.6 8.3 1e-22 81.1 5.7 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PepSY_TM_2 PF13703.1 EAQ93195.1 - 0.017 15.2 1.7 0.023 14.8 1.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM helix GRIM-19 PF06212.7 EAQ93195.1 - 0.23 11.1 3.2 3 7.5 0.0 2.2 2 0 0 2 2 2 0 GRIM-19 protein PepSY_TM PF03929.11 EAQ93195.1 - 7.3 7.2 9.6 14 6.3 6.6 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Ribosomal_S9 PF00380.14 EAQ93196.1 - 1.3e-35 122.2 0.2 1.5e-35 122.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Arf PF00025.16 EAQ93197.1 - 6.2e-43 146.0 0.0 7.4e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EAQ93197.1 - 1.2e-18 66.9 0.0 1.4e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ93197.1 - 8.6e-09 35.9 0.0 1.9e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EAQ93197.1 - 1.8e-07 30.5 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EAQ93197.1 - 1.4e-06 27.3 0.0 4.7e-06 25.5 0.0 1.8 1 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EAQ93197.1 - 5.2e-05 23.1 0.0 9.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAQ93197.1 - 9.8e-05 21.6 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EAQ93197.1 - 0.00019 20.9 0.0 0.0041 16.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EAQ93197.1 - 0.019 14.2 0.3 0.059 12.6 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EAQ93197.1 - 0.047 13.5 0.1 0.25 11.1 0.1 1.9 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EAQ93197.1 - 0.15 11.5 0.1 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb2_6 PF00562.23 EAQ93198.1 - 7.4e-114 380.4 0.0 9.4e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.11 EAQ93198.1 - 1.5e-24 85.5 0.0 3e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EAQ93198.1 - 2.7e-24 85.6 0.0 4.3e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EAQ93198.1 - 8.5e-24 83.2 0.0 2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.10 EAQ93198.1 - 1.2e-17 63.5 0.0 2.4e-17 62.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EAQ93198.1 - 3.2e-14 52.9 0.0 1.4e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EAQ93198.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 EAQ93198.1 - 0.15 11.9 0.2 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Tyrosinase PF00264.15 EAQ93199.1 - 1.5e-55 188.7 3.4 2.7e-55 187.9 0.6 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase DUF3661 PF12400.3 EAQ93200.1 - 2.8e-43 147.0 3.7 4.1e-43 146.5 2.6 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Herpes_gE PF02480.11 EAQ93200.1 - 0.075 11.2 0.0 1.9 6.6 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E RRM_1 PF00076.17 EAQ93201.1 - 8.9e-19 66.9 0.2 1.9e-18 65.8 0.1 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93201.1 - 3.5e-13 49.3 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93201.1 - 1.8e-09 37.3 0.1 2.8e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EAQ93202.1 - 7.9 6.2 12.8 2.5 7.8 3.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA PF00004.24 EAQ93203.1 - 9.3e-31 106.7 0.0 1.7e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ93203.1 - 7.5e-06 26.1 0.0 0.0006 19.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAQ93203.1 - 4.8e-05 23.1 0.1 0.00036 20.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EAQ93203.1 - 0.00022 21.2 0.0 0.00065 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EAQ93203.1 - 0.00022 21.2 0.1 0.0012 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EAQ93203.1 - 0.0021 17.0 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EAQ93203.1 - 0.0041 17.9 0.1 0.011 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAQ93203.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAQ93203.1 - 0.0092 15.7 0.2 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EAQ93203.1 - 0.013 15.4 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EAQ93203.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAQ93203.1 - 0.031 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAQ93203.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EAQ93203.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EAQ93203.1 - 0.061 13.3 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EAQ93203.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EAQ93203.1 - 0.093 12.4 0.7 9.4 5.8 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 EAQ93203.1 - 0.098 11.8 0.0 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EAQ93203.1 - 0.099 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cpn60_TCP1 PF00118.19 EAQ93204.1 - 6.4e-139 463.6 14.5 8e-139 463.3 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EAQ93204.1 - 0.0066 15.9 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Phage Tail Protein X DUF3924 PF13062.1 EAQ93204.1 - 0.047 13.5 0.2 0.69 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) DUF3546 PF12066.3 EAQ93205.1 - 1.1e-26 93.0 1.8 1.1e-26 93.0 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EAQ93205.1 - 5.3e-24 83.5 0.1 1.3e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EAQ93205.1 - 0.00019 21.7 9.6 0.00019 21.7 6.6 2.6 2 1 0 2 2 2 1 Arsenite-resistance protein 2 Mito_carr PF00153.22 EAQ93207.1 - 7.3e-60 198.6 0.0 5e-21 74.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KfrA_N PF11740.3 EAQ93207.1 - 0.029 14.8 0.7 0.072 13.5 0.5 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DEAD PF00270.24 EAQ93209.1 - 6.3e-41 139.6 0.0 2.1e-39 134.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ93209.1 - 5.8e-25 86.9 0.1 1.2e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 EAQ93209.1 - 0.0013 18.3 0.4 0.02 14.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3334) ResIII PF04851.10 EAQ93209.1 - 0.018 14.8 0.0 0.057 13.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CSL PF05207.8 EAQ93210.1 - 8.4e-15 54.0 1.2 1.2e-14 53.4 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EAQ93210.1 - 4.9e-14 51.8 0.2 9.4e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.15 EAQ93211.1 - 2.5e-116 386.7 4.8 2.9e-116 386.5 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 EAQ93211.1 - 0.065 12.9 0.2 0.23 11.2 0.0 2.0 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain TPR_19 PF14559.1 EAQ93211.1 - 0.53 10.6 3.2 2.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Alpha-L-AF_C PF06964.7 EAQ93212.1 - 1.1e-49 168.6 0.0 2e-49 167.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EAQ93212.1 - 2.5e-05 24.3 0.1 5.5e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain Abhydrolase_5 PF12695.2 EAQ93213.1 - 1.5e-06 28.0 1.3 1.7e-06 27.8 0.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EAQ93214.1 - 1.5e-25 89.7 30.1 1.5e-25 89.7 20.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ93214.1 - 1.5e-15 56.7 5.0 1.5e-15 56.7 3.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Mito_fiss_reg PF05308.6 EAQ93214.1 - 0.86 8.9 6.3 1.6 7.9 4.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator MULE PF10551.4 EAQ93215.1 - 8.9e-21 73.8 0.1 2.7e-20 72.3 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 EAQ93215.1 - 2.3e-07 29.6 0.1 3.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Glyco_hydro_12 PF01670.11 EAQ93216.1 - 2.3e-37 128.1 1.0 3.8e-37 127.4 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 adh_short PF00106.20 EAQ93216.1 - 5.3e-13 49.2 0.5 1e-12 48.3 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ93216.1 - 2.1e-07 30.7 0.3 3.7e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ93216.1 - 2.4e-06 27.4 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MULE PF10551.4 EAQ93217.1 - 8e-16 57.9 0.0 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EAQ93217.1 - 0.00014 20.5 0.0 0.00024 19.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family IATP PF04568.7 EAQ93218.1 - 7.4e-22 77.2 0.9 8.7e-22 77.0 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.7 EAQ93218.1 - 0.032 13.8 0.5 0.04 13.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) MutS_III PF05192.13 EAQ93218.1 - 0.048 13.4 0.1 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 MutS domain III NPV_P10 PF05531.7 EAQ93218.1 - 0.052 13.7 1.0 0.079 13.2 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 EAQ93218.1 - 0.054 12.9 2.9 0.093 12.2 2.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EAQ93218.1 - 0.096 12.6 6.4 0.12 12.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.6 EAQ93218.1 - 0.19 11.6 1.1 0.3 11.0 0.8 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 EAQ93218.1 - 0.2 11.4 6.9 0.33 10.7 4.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF1003 PF06210.6 EAQ93218.1 - 0.23 11.3 2.9 0.33 10.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Pox_A_type_inc PF04508.7 EAQ93218.1 - 0.42 10.5 3.2 0.67 9.8 1.3 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FYVE_2 PF02318.11 EAQ93218.1 - 0.55 10.1 2.5 0.74 9.7 1.7 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Nsp1_C PF05064.8 EAQ93219.1 - 1.2e-42 144.1 0.3 2.4e-42 143.2 0.2 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EAQ93219.1 - 3.1e-08 33.8 170.6 1.2 9.4 40.0 5.4 1 1 2 3 3 3 2 Nucleoporin FG repeat region TPR_MLP1_2 PF07926.7 EAQ93219.1 - 0.027 14.2 2.4 0.047 13.4 1.6 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EAQ93219.1 - 0.33 8.6 6.2 2.7 5.5 4.3 1.9 1 1 0 1 1 1 0 Myosin tail Spc7 PF08317.6 EAQ93219.1 - 0.73 8.4 3.7 7.1 5.1 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein V-SNARE PF05008.10 EAQ93219.1 - 1 9.5 4.0 2.4 8.4 0.1 2.8 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF4200 PF13863.1 EAQ93219.1 - 1.9 8.4 5.4 0.86 9.5 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GTP_EFTU PF00009.22 EAQ93221.1 - 1.1e-37 129.2 0.0 2e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EAQ93221.1 - 2.5e-37 126.8 0.3 5.1e-37 125.8 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EAQ93221.1 - 8.1e-10 38.6 0.1 1.8e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAQ93221.1 - 0.008 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF202 PF02656.10 EAQ93223.1 - 0.059 13.5 6.2 0.2 11.8 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4064 PF13273.1 EAQ93223.1 - 0.064 13.3 0.2 0.064 13.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF373 PF04123.8 EAQ93223.1 - 0.088 11.8 0.5 0.14 11.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF3329 PF11808.3 EAQ93223.1 - 0.11 12.5 0.5 3.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) Vpu PF00558.14 EAQ93223.1 - 2.1 7.9 4.3 4.2 6.9 0.9 2.3 2 0 0 2 2 2 0 Vpu protein ADK PF00406.17 EAQ93224.1 - 2.1e-44 151.0 0.0 2.8e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EAQ93224.1 - 2.8e-06 27.6 0.0 4.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAQ93224.1 - 1.3e-05 25.1 0.4 5e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAQ93224.1 - 1.5e-05 25.8 0.0 2.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EAQ93224.1 - 0.00027 20.3 0.1 0.049 13.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase COBRA PF04833.10 EAQ93224.1 - 0.05 13.3 0.1 3.1 7.5 0.1 2.2 2 0 0 2 2 2 0 COBRA-like protein PAS_7 PF12860.2 EAQ93224.1 - 0.14 12.2 0.3 0.95 9.4 0.0 2.3 3 0 0 3 3 3 0 PAS fold PCI PF01399.22 EAQ93225.1 - 7e-15 55.2 0.2 8e-14 51.8 0.1 2.3 2 0 0 2 2 2 1 PCI domain Pkinase PF00069.20 EAQ93226.1 - 2.2e-74 249.8 0.0 2.9e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93226.1 - 1.9e-36 125.4 0.0 2.6e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EAQ93226.1 - 4.2e-15 55.6 0.2 8.6e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EAQ93226.1 - 2.5e-10 39.8 0.0 3.2e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAQ93226.1 - 0.0048 15.9 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EAQ93226.1 - 0.0064 15.3 0.0 0.0096 14.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ADH_zinc_N_2 PF13602.1 EAQ93227.1 - 6.6e-14 52.8 0.0 1.6e-13 51.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EAQ93227.1 - 8.6e-12 44.7 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ93227.1 - 7e-06 25.7 0.8 2.4e-05 24.0 0.3 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Dimer_Tnp_hAT PF05699.9 EAQ93229.1 - 8.7e-13 47.7 0.1 2.1e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region p450 PF00067.17 EAQ93230.1 - 1.4e-25 89.7 0.0 1.4e-21 76.6 0.0 3.0 2 1 0 3 3 3 3 Cytochrome P450 ArfGap PF01412.13 EAQ93231.1 - 4.2e-34 116.8 1.7 5.9e-34 116.3 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EAQ93231.1 - 1.8e-13 50.6 1.0 5.6e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 PH domain PilJ PF13675.1 EAQ93231.1 - 0.0058 16.9 0.6 0.0058 16.9 0.4 2.7 2 0 0 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term PH_9 PF15410.1 EAQ93231.1 - 1.1 9.4 5.3 0.56 10.3 0.6 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Membr_traf_MHD PF10540.4 EAQ93233.1 - 1.4e-21 76.7 0.2 3.5e-21 75.4 0.1 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EAQ93233.1 - 2.2e-18 65.8 0.0 5.7e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Pyrophosphatase PF00719.14 EAQ93234.1 - 6.9e-52 175.0 0.1 8.6e-52 174.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pkinase PF00069.20 EAQ93236.1 - 1.2e-24 86.8 0.0 1.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93236.1 - 2e-13 50.0 0.0 3.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RVT_1 PF00078.22 EAQ93236.1 - 0.00072 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_V23 PF01802.12 EAQ93236.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein WD40 PF00400.27 EAQ93237.1 - 2.1e-06 27.3 1.8 0.041 13.7 0.1 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF2583 PF10762.4 EAQ93237.1 - 0.0023 18.0 1.4 0.0057 16.7 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2583) Ank PF00023.25 EAQ93238.1 - 7.9e-12 44.3 0.2 2.4e-06 27.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EAQ93238.1 - 3.5e-11 43.2 0.0 9.5e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PNP_UDP_1 PF01048.15 EAQ93238.1 - 1.5e-10 40.5 0.4 1.2e-09 37.5 0.2 2.5 2 1 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.7 EAQ93238.1 - 6.4e-10 38.9 0.3 1.6e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAQ93238.1 - 4.8e-09 36.4 2.8 7.6e-07 29.2 0.6 2.6 2 0 0 2 2 2 2 AAA ATPase domain Ank_4 PF13637.1 EAQ93238.1 - 1.6e-06 28.4 0.0 0.00064 20.1 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ93238.1 - 8.3e-06 25.8 0.0 3.4e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 EAQ93238.1 - 0.00015 21.8 0.0 0.00046 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAQ93238.1 - 0.00015 20.6 0.0 0.00029 19.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Ank_3 PF13606.1 EAQ93238.1 - 0.00027 20.8 0.0 0.091 13.0 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat AAA_14 PF13173.1 EAQ93238.1 - 0.0086 15.9 0.0 0.3 10.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAQ93238.1 - 0.041 13.5 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase PIF1 PF05970.9 EAQ93239.1 - 2.9e-06 26.4 0.0 3.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase HA PF03457.9 EAQ93239.1 - 0.0067 16.5 0.1 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain Indigoidine_A PF04227.7 EAQ93242.1 - 5.2e-71 239.2 0.0 8e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EAQ93242.1 - 1.2e-22 80.4 0.1 2.2e-21 76.2 0.0 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Cu_amine_oxid PF01179.15 EAQ93242.1 - 0.11 11.1 0.2 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain adh_short PF00106.20 EAQ93243.1 - 1.2e-18 67.5 1.1 1.2e-18 67.5 0.8 1.6 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ93243.1 - 6.7e-08 32.5 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ93243.1 - 1.4e-05 24.8 0.3 2.7e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 EAQ93244.1 - 9.5e-74 248.5 0.0 1.2e-73 248.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EAQ93244.1 - 1.6e-31 109.1 0.0 4.6e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EAQ93244.1 - 2.3e-05 24.7 0.1 0.0033 17.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAQ93244.1 - 0.00012 22.0 0.0 0.00052 19.9 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAQ93244.1 - 0.00016 21.6 0.1 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAQ93244.1 - 0.00027 19.5 0.2 0.00049 18.6 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EAQ93244.1 - 0.0011 19.1 0.2 0.0025 17.9 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAQ93244.1 - 0.0059 15.5 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EAQ93244.1 - 0.016 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EAQ93244.1 - 0.021 13.7 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EAQ93244.1 - 0.04 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EAQ93244.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EAQ93244.1 - 0.06 12.1 0.4 0.36 9.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EAQ93244.1 - 0.084 11.7 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 EAQ93244.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 ThiF family HET PF06985.6 EAQ93245.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 EAQ93245.1 - 3.3e-06 26.7 1.2 7.9e-06 25.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ93245.1 - 0.0013 18.2 1.3 0.0029 17.2 0.9 1.5 1 0 0 1 1 1 1 F-box domain Arrestin_N PF00339.24 EAQ93246.1 - 2.7e-16 59.7 0.0 7e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EAQ93246.1 - 4.2e-06 26.9 0.0 0.039 14.0 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain NicO PF03824.11 EAQ93247.1 - 0.0009 18.6 0.2 0.0009 18.6 0.1 1.9 2 0 0 2 2 2 1 High-affinity nickel-transport protein DAP10 PF07213.6 EAQ93247.1 - 0.08 12.6 0.1 0.08 12.6 0.1 2.1 2 0 0 2 2 2 0 DAP10 membrane protein DUF3533 PF12051.3 EAQ93247.1 - 0.15 10.7 2.2 0.22 10.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Sld5 PF05916.6 EAQ93248.1 - 3e-10 40.3 0.4 5.8e-10 39.4 0.3 1.5 1 0 0 1 1 1 1 GINS complex protein Aldolase_II PF00596.16 EAQ93250.1 - 2.2e-40 138.2 0.0 2.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 EAQ93251.1 - 3.3e-162 539.2 19.6 3.3e-162 539.2 13.6 1.4 2 0 0 2 2 2 1 Calreticulin family Aldedh PF00171.17 EAQ93252.1 - 5.8e-133 443.6 0.2 6.9e-133 443.3 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_16 PF13191.1 EAQ93253.1 - 1.2e-12 48.1 0.1 6.1e-12 45.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAQ93253.1 - 7.7e-12 45.4 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAQ93253.1 - 1.2e-08 35.2 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EAQ93253.1 - 0.00019 21.1 0.1 0.00078 19.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EAQ93253.1 - 0.00077 18.4 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.18 EAQ93253.1 - 0.0027 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EAQ93253.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EAQ93253.1 - 0.013 15.2 0.0 0.066 12.9 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain Tegument_dsDNA PF12818.2 EAQ93253.1 - 0.014 14.2 0.0 0.085 11.7 0.0 2.2 3 0 0 3 3 3 0 dsDNA viral tegument protein RNA_helicase PF00910.17 EAQ93253.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EAQ93253.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EAQ93253.1 - 0.015 14.2 0.0 0.042 12.8 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Cdc6_C PF09079.6 EAQ93253.1 - 0.018 14.7 0.1 0.078 12.7 0.0 2.1 2 0 0 2 2 2 0 CDC6, C terminal T2SE PF00437.15 EAQ93253.1 - 0.027 13.3 0.2 0.074 11.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.9 EAQ93253.1 - 0.029 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EAQ93253.1 - 0.049 12.5 0.0 0.099 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 EAQ93253.1 - 0.06 12.3 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Trypan_PARP PF05887.6 EAQ93253.1 - 0.14 11.9 3.2 0.27 11.0 2.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AIG1 PF04548.11 EAQ93253.1 - 0.18 10.8 2.9 3.3 6.7 0.5 2.8 2 1 0 2 2 2 0 AIG1 family Aminotran_5 PF00266.14 EAQ93254.1 - 7.4e-30 103.9 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EAQ93254.1 - 8e-23 80.4 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EAQ93254.1 - 1.5e-14 53.6 0.0 3.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MBOAT_2 PF13813.1 EAQ93255.1 - 3e-11 43.2 0.8 3e-11 43.2 0.6 3.6 5 1 0 5 5 5 1 Membrane bound O-acyl transferase family Antimicrobial12 PF08107.6 EAQ93255.1 - 0.069 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Pleurocidin family Zn_clus PF00172.13 EAQ93256.1 - 4.2e-08 32.9 11.1 8.4e-08 32.0 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EAQ93256.1 - 0.75 8.7 4.6 1.2 8.0 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter URO-D PF01208.12 EAQ93258.1 - 9.6e-122 406.1 0.0 1.1e-121 405.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 EAQ93258.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Phloem filament protein PP1 DUF3602 PF12223.3 EAQ93260.1 - 5.8e-17 61.8 12.3 3.4e-14 52.9 1.4 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mif2_N PF15624.1 EAQ93261.1 - 1.7 9.2 5.9 2.1 8.9 4.1 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Nucleo_P87 PF07267.6 EAQ93261.1 - 7.4 5.1 8.7 8.2 4.9 6.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Transglut_core PF01841.14 EAQ93263.1 - 0.1 12.8 0.5 0.24 11.6 0.3 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily Yeast-kill-tox PF09207.6 EAQ93263.1 - 5.5 7.4 8.3 6.9 7.1 0.5 2.9 3 0 0 3 3 3 0 Yeast killer toxin RhoGEF PF00621.15 EAQ93264.1 - 2.2e-34 118.8 0.1 6.1e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EAQ93264.1 - 1.8e-08 34.1 3.4 1.8e-08 34.1 2.3 2.1 2 1 0 2 2 2 1 BAR domain Telomerase_RBD PF12009.3 EAQ93265.1 - 1.9e-37 128.1 1.5 1.2e-36 125.6 1.0 2.1 1 1 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EAQ93265.1 - 0.042 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Reo_sigmaC PF04582.7 EAQ93266.1 - 0.22 10.6 2.7 0.38 9.8 1.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Gp58 PF07902.6 EAQ93266.1 - 1.9 6.5 2.2 3 5.9 1.5 1.1 1 0 0 1 1 1 0 gp58-like protein Glyco_hydro_7 PF00840.15 EAQ93270.1 - 3.6e-196 651.6 12.3 4.2e-196 651.4 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FolB PF02152.13 EAQ93271.1 - 2e-17 63.4 0.0 3.5e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase TerD PF02342.13 EAQ93272.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 TerD domain UDPGP PF01704.13 EAQ93273.1 - 3.2e-185 615.6 0.3 3.7e-185 615.4 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EAQ93273.1 - 0.061 11.8 0.3 0.21 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) PilO PF04350.8 EAQ93273.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Pilus assembly protein, PilO ING PF12998.2 EAQ93274.1 - 8e-24 83.9 7.6 1.2e-23 83.3 5.3 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EAQ93274.1 - 3e-07 30.0 10.1 4.8e-07 29.3 7.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EAQ93274.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain IFT46_B_C PF12317.3 EAQ93274.1 - 0.057 12.7 1.4 0.084 12.2 1.0 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DivIC PF04977.10 EAQ93274.1 - 0.66 9.5 4.4 9.3 5.8 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EAQ93274.1 - 0.82 9.2 4.1 1.6 8.2 2.8 1.4 1 0 0 1 1 1 0 IncA protein DUF733 PF05306.6 EAQ93274.1 - 2.5 8.4 5.7 0.48 10.7 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF733) DUF342 PF03961.8 EAQ93274.1 - 5.2 5.3 5.3 8.1 4.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hist_deacetyl PF00850.14 EAQ93275.1 - 8.1e-80 268.4 0.1 1.3e-79 267.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.11 EAQ93276.1 - 6.7e-09 34.9 24.6 6.7e-09 34.9 17.0 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily WW PF00397.21 EAQ93277.1 - 8.4e-10 38.3 0.1 3.2e-09 36.4 0.1 2.1 1 0 0 1 1 1 1 WW domain PMM PF03332.8 EAQ93278.1 - 3.8e-104 347.0 0.4 4.4e-104 346.8 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EAQ93278.1 - 0.00041 19.9 0.0 0.0022 17.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EAQ93278.1 - 0.013 14.8 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EAQ93278.1 - 0.016 14.3 0.1 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Na_Ca_ex PF01699.19 EAQ93279.1 - 3e-20 72.2 3.6 3e-20 72.2 2.5 1.9 1 1 1 2 2 2 1 Sodium/calcium exchanger protein DUF347 PF03988.7 EAQ93279.1 - 0.35 10.7 5.7 1.3 9.0 0.2 2.8 2 1 0 2 2 2 0 Repeat of Unknown Function (DUF347) Na_Ca_ex PF01699.19 EAQ93280.1 - 6.1e-25 87.4 14.9 6.1e-25 87.4 10.3 1.6 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Cnd2 PF05786.9 EAQ93281.1 - 1.5e-213 711.3 0.6 2e-213 711.0 0.4 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 HMG_box PF00505.14 EAQ93284.1 - 2.1e-10 40.6 2.0 4.3e-10 39.7 0.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ93284.1 - 9.1e-08 32.3 0.2 9.1e-08 32.3 0.2 1.7 2 0 0 2 2 2 1 HMG-box domain Tol_Tol_Ttg2 PF05494.7 EAQ93284.1 - 0.039 13.4 0.2 0.058 12.9 0.2 1.2 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 HAMP PF00672.20 EAQ93286.1 - 8.6e-38 128.3 12.4 1.7e-08 34.5 0.0 6.2 5 1 1 6 6 6 5 HAMP domain HATPase_c PF02518.21 EAQ93286.1 - 1e-29 102.4 0.1 4.1e-29 100.5 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAQ93286.1 - 1.5e-27 95.8 0.7 7.3e-26 90.3 0.2 2.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EAQ93286.1 - 3.9e-18 65.2 0.5 3.9e-18 65.2 0.4 3.4 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF883 PF05957.8 EAQ93286.1 - 0.008 16.5 8.0 0.83 10.0 0.1 4.4 4 0 0 4 4 4 2 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 EAQ93286.1 - 0.044 12.2 14.3 0.079 11.4 0.1 3.7 2 1 2 4 4 4 0 AAA domain NAAA-beta PF15508.1 EAQ93286.1 - 0.11 12.8 3.3 7.7 6.9 0.1 4.9 3 2 2 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2365 PF10157.4 EAQ93286.1 - 0.26 11.1 9.4 3.5 7.5 0.0 5.4 4 1 2 6 6 6 0 Uncharacterized conserved protein (DUF2365) Dus PF01207.12 EAQ93288.1 - 5.9e-40 137.0 0.1 1.6e-39 135.5 0.1 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TRP PF06011.7 EAQ93289.1 - 1.7e-133 445.4 14.7 2.2e-133 445.0 10.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAQ93289.1 - 1.8e-39 135.0 3.4 2.7e-39 134.4 2.4 1.3 1 0 0 1 1 1 1 ML-like domain Tmemb_14 PF03647.8 EAQ93292.1 - 3.8e-24 84.8 6.4 4.2e-24 84.7 4.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EAQ93292.1 - 0.16 12.2 0.6 0.37 11.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) DUF3792 PF12670.2 EAQ93292.1 - 1.3 8.9 5.5 1.1 9.1 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF1427 PF07235.6 EAQ93292.1 - 6.2 6.9 6.8 2.5 8.2 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1427) Prefoldin_2 PF01920.15 EAQ93293.1 - 8.6e-25 86.5 4.1 9.8e-25 86.3 2.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.4 EAQ93293.1 - 0.0073 15.8 0.5 2.4 7.8 0.0 2.1 2 0 0 2 2 2 2 Predicted coiled-coil protein (DUF2205) Taxilin PF09728.4 EAQ93293.1 - 0.011 14.8 1.4 1.2 8.1 0.1 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF2089 PF09862.4 EAQ93293.1 - 0.034 13.9 0.5 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) UBN2 PF14223.1 EAQ93293.1 - 0.04 13.7 0.3 0.48 10.2 0.0 2.0 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type TPR_MLP1_2 PF07926.7 EAQ93293.1 - 0.071 12.8 2.4 0.55 9.9 0.1 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein p25-alpha PF05517.7 EAQ93293.1 - 0.081 13.1 0.6 3.4 7.9 0.0 2.1 2 0 0 2 2 2 0 p25-alpha DUF2956 PF11169.3 EAQ93293.1 - 0.1 12.5 0.6 0.1 12.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Prefoldin PF02996.12 EAQ93293.1 - 0.11 12.1 3.6 1.3 8.6 0.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF148 PF02520.12 EAQ93293.1 - 0.12 12.1 3.0 0.3 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 CBFD_NFYB_HMF PF00808.18 EAQ93294.1 - 2e-29 101.4 1.1 2.6e-29 101.0 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAQ93294.1 - 3.6e-07 30.1 0.1 5.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EAQ93294.1 - 0.00083 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EAQ93294.1 - 0.00093 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EAQ93294.1 - 0.035 14.4 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GMC_oxred_N PF00732.14 EAQ93295.1 - 1.1e-47 162.6 0.0 1.4e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAQ93295.1 - 4.7e-42 143.6 0.0 9.4e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAQ93295.1 - 1.3e-05 24.2 7.6 0.0023 16.8 4.2 2.5 2 1 1 3 3 3 2 FAD binding domain DAO PF01266.19 EAQ93295.1 - 1.6e-05 24.0 0.3 3.7e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAQ93295.1 - 0.00071 19.5 0.3 0.002 18.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EAQ93295.1 - 0.008 14.8 0.7 0.011 14.3 0.5 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EAQ93295.1 - 0.012 15.5 0.7 0.028 14.2 0.4 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ93295.1 - 0.013 15.6 0.7 0.068 13.2 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ93295.1 - 0.022 13.8 0.4 0.046 12.8 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Soyouz_module PF14313.1 EAQ93295.1 - 0.025 14.1 0.1 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Lycopene_cycl PF05834.7 EAQ93295.1 - 0.033 13.1 0.3 0.053 12.4 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 EAQ93295.1 - 0.04 13.7 0.1 0.15 11.8 0.3 1.8 2 0 0 2 2 2 0 ThiF family GIDA PF01134.17 EAQ93295.1 - 0.088 11.6 1.2 0.14 10.9 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EAQ93295.1 - 0.28 10.1 0.8 0.51 9.3 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EAQ93295.1 - 0.37 9.1 1.2 0.52 8.7 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 EAQ93296.1 - 6e-23 81.0 0.1 8.7e-23 80.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ93296.1 - 8.4e-07 28.8 10.4 1.5e-06 27.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.1 EAQ93296.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 MFS_1 PF07690.11 EAQ93297.1 - 2.2e-11 43.0 27.4 5e-11 41.9 18.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily RuvA_C PF07499.8 EAQ93297.1 - 0.14 12.3 1.6 6.5 6.9 0.0 2.6 2 1 0 2 2 2 0 RuvA, C-terminal domain ADH_N PF08240.7 EAQ93299.1 - 2.4e-27 94.8 4.0 4.7e-27 93.8 2.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ93299.1 - 3.9e-17 62.0 0.1 6.5e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ93299.1 - 0.00094 20.0 0.0 0.0021 18.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EAQ93299.1 - 0.0019 17.8 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EAQ93299.1 - 0.0046 16.1 0.1 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EAQ93299.1 - 0.11 12.1 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BNR_2 PF13088.1 EAQ93300.1 - 0.0022 17.3 0.2 0.084 12.1 0.1 2.2 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EAQ93300.1 - 6.3 7.0 17.1 1 9.4 0.1 4.2 4 0 0 4 4 4 0 BNR/Asp-box repeat RRN3 PF05327.6 EAQ93301.1 - 2.3e-168 560.8 0.0 2.3e-168 560.8 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.16 EAQ93301.1 - 0.3 11.0 12.0 3.1 7.8 8.3 2.4 1 1 0 1 1 1 0 bZIP transcription factor WSC PF01822.14 EAQ93303.1 - 1.4e-75 249.2 71.5 5.6e-20 71.0 8.5 5.3 4 1 1 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 EAQ93303.1 - 1.7e-28 99.3 0.0 1.2e-27 96.5 0.0 2.3 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAQ93303.1 - 2.7e-20 72.2 0.0 4.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) LRR_4 PF12799.2 EAQ93304.1 - 0.12 12.0 1.7 37 4.0 0.3 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Ank PF00023.25 EAQ93305.1 - 1.4e-44 147.7 25.1 2.4e-07 30.2 0.1 8.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_2 PF12796.2 EAQ93305.1 - 7.4e-43 144.8 12.7 1.1e-14 54.5 0.2 5.0 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ93305.1 - 8.6e-26 89.3 14.1 1.1e-07 31.8 0.2 6.5 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAQ93305.1 - 2.1e-25 88.6 7.8 1.5e-07 31.6 0.1 6.7 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ93305.1 - 1.2e-24 83.9 10.5 0.0049 16.9 0.0 8.2 8 1 0 8 8 8 6 Ankyrin repeat ABC_tran PF00005.22 EAQ93305.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF3789 PF12664.2 EAQ93305.1 - 0.053 12.8 0.3 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Competence PF03772.11 EAQ93305.1 - 0.26 10.3 6.6 0.053 12.5 1.4 1.9 2 0 0 2 2 2 0 Competence protein Oxysterol_BP PF01237.13 EAQ93306.1 - 9e-45 152.6 0.0 2.4e-35 121.6 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein CotJA PF11007.3 EAQ93306.1 - 0.082 12.5 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) Prenyltrans_2 PF13249.1 EAQ93307.1 - 5.7e-35 120.1 0.5 2.4e-14 53.7 0.0 4.9 2 2 3 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 EAQ93307.1 - 7.9e-33 111.7 6.7 1.5e-09 37.2 0.0 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EAQ93307.1 - 3.7e-29 100.9 0.1 9.2e-13 48.1 0.1 5.5 3 2 3 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 EAQ93307.1 - 3.6e-06 26.3 0.0 0.23 10.5 0.0 4.6 2 1 2 4 4 4 2 Pectic acid lyase A2M_comp PF07678.9 EAQ93307.1 - 0.0012 18.1 0.0 0.044 13.0 0.0 3.0 2 1 1 3 3 3 1 A-macroglobulin complement component GRASP55_65 PF04495.9 EAQ93309.1 - 6.6e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EAQ93309.1 - 1.1e-05 25.2 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EAQ93309.1 - 6.6e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) RhoGEF PF00621.15 EAQ93310.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 RhoGEF domain TFIIA PF03153.8 EAQ93310.1 - 2.6 7.8 9.8 0.7 9.7 4.8 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SBDS PF01172.13 EAQ93311.1 - 1.1e-23 82.8 0.0 1.3e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OPA3 PF07047.7 EAQ93314.1 - 1e-24 86.8 3.9 1.6e-24 86.1 2.7 1.4 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2681 PF10883.3 EAQ93314.1 - 0.055 13.6 0.2 0.055 13.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF16 PF01519.11 EAQ93314.1 - 0.057 13.6 6.2 0.91 9.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4140 PF13600.1 EAQ93314.1 - 0.46 10.9 6.3 0.84 10.1 0.7 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF607 PF04678.8 EAQ93314.1 - 1.6 8.6 4.2 3.2 7.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 OmpH PF03938.9 EAQ93314.1 - 5.9 6.7 10.7 12 5.8 2.9 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Histone_HNS PF00816.16 EAQ93314.1 - 6.8 7.2 11.3 6.1 7.4 1.2 2.8 2 1 0 2 2 2 0 H-NS histone family Mnd1 PF03962.10 EAQ93314.1 - 8.9 5.9 13.7 7.3 6.1 2.7 2.0 2 0 0 2 2 2 0 Mnd1 family Pkinase PF00069.20 EAQ93315.1 - 7.4e-68 228.5 0.3 2.2e-67 226.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93315.1 - 6.3e-41 140.1 0.0 9.2e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ93315.1 - 8.6e-10 38.0 0.0 1.6e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EAQ93315.1 - 1e-07 31.8 0.1 0.00021 21.1 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EAQ93315.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ93316.1 - 1e-14 54.8 0.2 4.7e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family FAD_binding_3 PF01494.14 EAQ93316.1 - 7.4e-13 48.2 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ATG16 PF08614.6 EAQ93317.1 - 0.0014 18.5 18.0 0.0014 18.5 12.5 2.4 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Sec8_exocyst PF04048.9 EAQ93317.1 - 0.0019 17.8 5.4 0.28 10.8 0.2 2.1 2 0 0 2 2 2 2 Sec8 exocyst complex component specific domain BLOC1_2 PF10046.4 EAQ93317.1 - 0.0036 17.4 4.6 0.0036 17.4 3.2 2.0 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 EAQ93317.1 - 0.0066 16.2 6.7 0.0066 16.2 4.6 2.8 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF3510 PF12022.3 EAQ93317.1 - 0.013 15.6 0.9 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) WXG100 PF06013.7 EAQ93317.1 - 0.023 14.7 3.5 1.9 8.5 0.1 2.7 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF641 PF04859.7 EAQ93317.1 - 0.29 10.8 21.8 0.41 10.3 5.6 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FH2 PF02181.18 EAQ93317.1 - 0.33 9.7 12.0 0.081 11.8 2.3 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF1706 PF08020.6 EAQ93317.1 - 0.46 9.9 6.3 0.21 11.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1706) AF0941-like PF14591.1 EAQ93317.1 - 0.51 10.4 13.3 0.04 13.9 4.0 2.2 2 1 0 2 2 2 0 AF0941-like DivIC PF04977.10 EAQ93317.1 - 0.59 9.6 14.6 0.049 13.1 4.6 2.7 2 1 1 3 3 3 0 Septum formation initiator Prefoldin PF02996.12 EAQ93317.1 - 0.67 9.6 13.8 0.12 12.0 2.7 3.3 2 2 2 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.5 EAQ93317.1 - 0.94 9.5 12.6 1.8 8.6 3.6 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1825 PF08855.5 EAQ93317.1 - 0.95 9.4 9.2 0.39 10.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) DUF922 PF06037.6 EAQ93317.1 - 1 8.6 12.4 0.026 13.8 1.6 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) GP41 PF00517.12 EAQ93317.1 - 2.6 7.5 4.9 0.97 8.9 1.4 1.6 2 0 0 2 2 2 0 Retroviral envelope protein AAA_13 PF13166.1 EAQ93317.1 - 3 6.1 16.1 13 4.0 11.2 1.8 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.3 EAQ93317.1 - 3.7 6.7 19.2 4.8 6.3 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MAD PF05557.8 EAQ93317.1 - 5.2 5.0 27.1 0.023 12.7 9.1 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Spc7 PF08317.6 EAQ93317.1 - 6.8 5.2 18.8 1.3 7.6 5.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein P4Ha_N PF08336.6 EAQ93317.1 - 8.1 6.2 13.1 6.4 6.6 0.7 2.6 2 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region APG6 PF04111.7 EAQ93317.1 - 8.4 5.3 26.1 5.9 5.8 9.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4239 PF14023.1 EAQ93317.1 - 9.9 5.4 7.9 1.2 8.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Abhydrolase_6 PF12697.2 EAQ93318.1 - 1.7e-17 64.1 0.0 2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ93318.1 - 7.9e-08 32.1 0.0 8.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAQ93318.1 - 1.1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EAQ93318.1 - 0.0017 16.9 0.0 0.0023 16.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 WD40 PF00400.27 EAQ93319.1 - 6.7e-23 79.6 7.7 2e-08 33.8 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Rax2 PF12768.2 EAQ93319.1 - 0.0031 16.7 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity RRM_5 PF13893.1 EAQ93320.1 - 2.2e-09 37.0 0.1 3.2e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ93320.1 - 2.7e-08 33.3 0.0 7.7e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93320.1 - 2.5e-05 24.1 0.0 5.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EAQ93320.1 - 0.00066 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EAQ93320.1 - 0.0095 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 Glyco_hydro_47 PF01532.15 EAQ93322.1 - 4.1e-158 526.7 0.0 5.6e-158 526.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EAQ93322.1 - 0.0034 16.7 0.3 0.0075 15.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) DUF883 PF05957.8 EAQ93322.1 - 0.052 13.9 0.2 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AA_permease PF00324.16 EAQ93323.1 - 1.7e-138 461.9 33.8 3.7e-136 454.2 20.3 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAQ93323.1 - 2.1e-37 128.6 30.5 3e-37 128.1 21.2 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EAQ93323.1 - 0.16 10.4 0.1 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Herpes_UL32 PF06070.6 EAQ93325.1 - 1.6 7.0 4.4 1.9 6.8 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Glyco_transf_25 PF01755.12 EAQ93327.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) MFS_1 PF07690.11 EAQ93328.1 - 1.1e-05 24.3 8.0 2.5e-05 23.1 5.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.2 EAQ93329.1 - 1.2e-05 24.9 0.5 2.5e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAQ93329.1 - 0.00012 21.6 2.1 0.00048 19.7 1.4 2.0 1 1 0 1 1 1 1 F-box domain AMP-binding PF00501.23 EAQ93330.1 - 1.3e-90 303.7 0.0 1.6e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ93330.1 - 7.1e-16 58.9 0.5 1.7e-15 57.7 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.6 EAQ93331.1 - 4.7e-80 268.9 0.0 2.2e-79 266.6 0.0 1.8 1 1 0 1 1 1 1 ATP11 protein Totivirus_coat PF05518.6 EAQ93331.1 - 0.39 8.4 3.7 0.49 8.1 2.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF2360 PF10152.4 EAQ93331.1 - 0.73 10.1 4.7 1 9.6 3.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) peroxidase PF00141.18 EAQ93332.1 - 3.2e-49 167.5 0.0 4.8e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase TPR_16 PF13432.1 EAQ93333.1 - 2.9e-06 27.7 0.9 0.0024 18.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Syja_N PF02383.13 EAQ93334.1 - 1.1e-81 274.0 0.0 1.5e-81 273.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EAQ93334.1 - 7.3e-26 91.6 0.1 1.3e-25 90.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 14-3-3 PF00244.15 EAQ93336.1 - 4.1e-114 379.5 0.6 5.2e-114 379.2 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EAQ93336.1 - 0.011 15.6 0.2 5.4 7.0 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF837 PF05769.6 EAQ93336.1 - 0.027 14.0 0.5 5 6.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Lipase_3 PF01764.20 EAQ93337.1 - 0.03 13.9 0.0 6.8 6.3 0.0 2.2 1 1 1 2 2 2 0 Lipase (class 3) DUF2360 PF10152.4 EAQ93337.1 - 5.5 7.2 8.1 8 6.7 5.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EAQ93337.1 - 10 5.4 12.6 12 5.1 8.7 1.1 1 0 0 1 1 1 0 Vta1 like TUG-UBL1 PF11470.3 EAQ93340.1 - 1.6e-25 88.8 0.0 3.3e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EAQ93340.1 - 0.0012 18.8 0.0 0.0059 16.6 0.0 2.2 3 0 0 3 3 3 1 UBX domain RBD PF02196.10 EAQ93340.1 - 0.036 13.8 0.1 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain ATP-synt_B PF00430.13 EAQ93340.1 - 2.2 8.0 7.9 1.2 8.9 2.6 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Proteasome PF00227.21 EAQ93341.1 - 5.8e-38 130.0 0.0 6.5e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.15 EAQ93342.1 - 2.3e-62 210.0 6.5 2.3e-62 210.0 4.5 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAQ93342.1 - 2.1e-45 154.4 5.0 2.1e-45 154.4 3.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAQ93342.1 - 3.8e-33 115.7 0.0 1.4e-32 113.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ93342.1 - 3.5e-23 81.3 0.0 6.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAQ93342.1 - 1.1e-19 69.6 0.1 3.1e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAQ93342.1 - 4.3e-17 62.9 0.0 1.4e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ93342.1 - 1.7e-09 37.6 0.7 5.5e-06 26.1 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAQ93342.1 - 0.008 16.4 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EAQ93342.1 - 0.09 12.6 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TBCA PF02970.11 EAQ93343.1 - 8.4e-19 67.4 11.5 8.4e-19 67.4 7.9 1.5 1 1 1 2 2 2 1 Tubulin binding cofactor A DUF4404 PF14357.1 EAQ93343.1 - 0.031 14.6 6.7 0.65 10.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) CALCOCO1 PF07888.6 EAQ93343.1 - 0.041 12.1 9.2 0.046 12.0 6.4 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Bacillus_HBL PF05791.6 EAQ93343.1 - 0.051 12.9 3.8 0.05 12.9 1.6 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2972 PF11186.3 EAQ93343.1 - 0.057 13.3 3.8 0.15 11.9 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) Tropomyosin PF00261.15 EAQ93343.1 - 0.096 11.7 17.6 2.2 7.3 12.2 2.0 1 1 0 1 1 1 0 Tropomyosin AAA_13 PF13166.1 EAQ93343.1 - 0.13 10.6 7.8 0.15 10.5 5.4 1.1 1 0 0 1 1 1 0 AAA domain RRF_GI PF12614.3 EAQ93343.1 - 0.35 10.6 2.7 0.34 10.7 1.4 1.3 1 1 0 1 1 1 0 Ribosome recycling factor Fib_alpha PF08702.5 EAQ93343.1 - 0.42 10.7 4.3 0.59 10.2 2.9 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HalX PF08663.5 EAQ93343.1 - 0.74 9.8 4.8 6.2 6.8 0.1 2.6 2 1 1 3 3 2 0 HalX domain Exonuc_VII_L PF02601.10 EAQ93343.1 - 0.88 8.7 5.5 6.3 5.8 3.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 EAQ93343.1 - 1.1 9.2 13.0 3.8 7.4 9.0 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.14 EAQ93343.1 - 1.2 8.5 9.3 0.086 12.2 1.8 1.9 1 1 1 2 2 2 0 Ribosome recycling factor IncA PF04156.9 EAQ93343.1 - 1.3 8.5 11.1 2.9 7.4 7.7 1.5 1 1 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EAQ93343.1 - 1.4 8.7 17.5 2 8.2 6.2 2.2 1 1 1 2 2 2 0 Tropomyosin like TPR_MLP1_2 PF07926.7 EAQ93343.1 - 2.4 7.9 14.4 46 3.7 10.0 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4398 PF14346.1 EAQ93343.1 - 8.3 6.5 9.8 0.6 10.1 2.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4398) XhlA PF10779.4 EAQ93343.1 - 9.6 6.1 14.6 5.9 6.8 0.9 3.1 1 1 2 3 3 3 0 Haemolysin XhlA THOC7 PF05615.8 EAQ93344.1 - 1.8e-42 144.8 5.9 1.8e-42 144.8 4.1 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 RTBV_P46 PF06216.6 EAQ93344.1 - 0.24 10.2 7.7 0.079 11.7 0.7 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein PilO PF04350.8 EAQ93344.1 - 0.35 10.7 4.1 1.9 8.3 0.3 2.7 1 1 1 2 2 2 0 Pilus assembly protein, PilO Sigma70_ner PF04546.8 EAQ93344.1 - 0.62 9.6 11.4 0.33 10.5 2.8 2.9 1 1 2 3 3 3 0 Sigma-70, non-essential region zf-C4H2 PF10146.4 EAQ93344.1 - 1.5 8.8 9.7 4.5 7.2 1.3 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein AAA_13 PF13166.1 EAQ93344.1 - 1.9 6.8 6.2 3.1 6.1 4.3 1.3 1 0 0 1 1 1 0 AAA domain MSA-2c PF12238.3 EAQ93344.1 - 2.7 7.5 11.1 0.022 14.4 1.7 1.9 2 1 1 3 3 3 0 Merozoite surface antigen 2c Elongin_A PF06881.6 EAQ93345.1 - 2.6e-16 59.9 0.7 4.9e-16 59.0 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.18 EAQ93346.1 - 7.6e-23 79.6 0.1 9e-23 79.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAQ93346.1 - 2.2e-11 43.2 0.1 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAQ93346.1 - 0.093 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Band_7 PF01145.20 EAQ93347.1 - 1.7e-23 83.4 2.0 2.3e-23 83.0 1.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.1 EAQ93348.1 - 1.8e-30 104.8 1.1 1.8e-30 104.8 0.8 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EAQ93348.1 - 2e-22 78.5 0.0 3.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93348.1 - 2.1e-17 62.8 0.0 4.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93348.1 - 3.3e-06 26.8 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EAQ93348.1 - 0.0001 21.4 5.2 0.0001 21.4 3.6 2.6 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal Myco_19_kDa PF05481.7 EAQ93348.1 - 0.28 10.9 2.7 32 4.3 2.1 2.3 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF3135 PF11333.3 EAQ93348.1 - 0.43 10.7 2.8 0.68 10.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) CorA PF01544.13 EAQ93349.1 - 1.7e-37 129.0 3.3 5.1e-35 120.9 2.3 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3237 PF11578.3 EAQ93351.1 - 1.5e-24 85.9 0.0 1.7e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.12 EAQ93352.1 - 4.8e-24 84.9 0.4 1.9e-18 66.7 0.2 3.1 3 0 0 3 3 3 3 Mob1/phocein family DUF1180 PF06679.7 EAQ93352.1 - 6.8 6.5 6.8 12 5.7 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Leo1 PF04004.8 EAQ93353.1 - 3.4e-18 65.9 10.2 1.6e-17 63.7 0.0 3.1 2 1 1 3 3 3 2 Leo1-like protein BRO1 PF03097.13 EAQ93354.1 - 9.3e-05 21.3 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.10 EAQ93355.1 - 2.8e-132 441.8 24.0 1.7e-83 281.0 6.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family SURF4 PF02077.10 EAQ93357.1 - 1.1e-89 300.4 8.7 1.3e-89 300.1 6.0 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 EAQ93357.1 - 0.46 10.6 14.7 0.47 10.6 0.7 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Wzy_C PF04932.10 EAQ93357.1 - 0.58 9.9 11.0 0.31 10.7 2.7 2.3 2 0 0 2 2 2 0 O-Antigen ligase FA_desaturase PF00487.19 EAQ93357.1 - 7.9 5.8 13.1 4.2 6.7 5.1 2.5 1 1 1 2 2 2 0 Fatty acid desaturase Zn_clus PF00172.13 EAQ93358.1 - 1.1e-06 28.4 9.8 3.4e-06 26.8 6.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.7 EAQ93359.1 - 3.9e-103 344.7 7.6 7e-103 343.8 5.3 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EAQ93359.1 - 6e-27 92.5 0.5 4.3e-10 39.0 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 EAQ93360.1 - 9.9e-18 64.8 1.6 1.7e-17 64.1 1.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAQ93360.1 - 6.5e-15 55.6 0.5 8.4e-14 51.9 0.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3336 PF11815.3 EAQ93362.1 - 1e-30 106.1 0.0 2.1e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EAQ93362.1 - 2.1e-13 50.6 0.1 4.5e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Aida_N PF08910.5 EAQ93362.1 - 0.034 14.3 0.1 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 Aida N-terminus SNF2_N PF00176.18 EAQ93363.1 - 1.2e-17 63.7 0.2 2.4e-10 39.7 0.3 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAQ93363.1 - 2.2e-14 53.0 0.2 7.1e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VMA21 PF09446.5 EAQ93364.1 - 2e-16 59.6 7.7 2.7e-16 59.2 5.4 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF973 PF06157.6 EAQ93364.1 - 0.016 14.2 0.3 0.019 13.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2406 PF10295.4 EAQ93365.1 - 4.3e-22 78.4 0.3 4.3e-22 78.4 0.2 2.5 3 1 0 3 3 3 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.13 EAQ93367.1 - 2.6e-33 113.6 0.3 3e-33 113.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EAQ93367.1 - 0.0018 18.1 0.1 0.74 9.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF3703 PF12487.3 EAQ93367.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) APH PF01636.18 EAQ93369.1 - 7.1e-12 45.5 0.7 3.8e-11 43.1 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ93369.1 - 0.0069 15.9 0.8 0.11 12.0 0.2 2.3 2 1 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EAQ93369.1 - 0.029 13.5 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain CHASE PF03924.8 EAQ93369.1 - 0.039 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 CHASE domain G6PD_C PF02781.11 EAQ93370.1 - 1.3e-134 447.6 0.0 1.8e-134 447.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EAQ93370.1 - 1.2e-55 188.5 0.1 2.1e-55 187.7 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med14 PF08638.6 EAQ93371.1 - 4.9e-78 260.8 0.0 4.9e-78 260.8 0.0 1.9 2 0 0 2 2 2 1 Mediator complex subunit MED14 PAT1 PF09770.4 EAQ93371.1 - 0.25 9.5 45.2 0.38 8.9 31.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EAQ93371.1 - 2.8 7.7 27.4 4.7 6.9 19.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amino_oxidase PF01593.19 EAQ93372.1 - 3.2e-10 39.6 0.0 6.3e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAQ93372.1 - 2.2e-09 37.2 0.0 8.4e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAQ93372.1 - 6.5e-09 35.1 0.2 2.4e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAQ93372.1 - 0.0032 17.8 0.1 0.074 13.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ93372.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EAQ93372.1 - 0.055 13.2 0.2 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-CCCH_2 PF14608.1 EAQ93373.1 - 4.8e-06 26.3 9.9 4.8e-06 26.3 6.9 5.5 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Glyco_hydro_20 PF00728.17 EAQ93374.1 - 1.2e-85 287.8 0.0 1.5e-85 287.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EAQ93374.1 - 1.7e-24 86.9 0.0 4e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EAQ93374.1 - 2.2e-06 28.1 0.0 0.0032 17.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 DUF3951 PF13131.1 EAQ93374.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) p450 PF00067.17 EAQ93375.1 - 2.4e-61 207.6 0.0 3.3e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 EAQ93376.1 - 1.3e-16 60.4 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EAQ93376.1 - 1.8e-07 30.1 0.0 2.4e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EAQ93376.1 - 0.054 12.5 0.1 0.43 9.5 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF454 PF04304.8 EAQ93377.1 - 0.035 14.1 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF454) GVQW PF13900.1 EAQ93378.1 - 4.5 7.3 6.2 1.6 8.8 1.9 2.0 2 0 0 2 2 2 0 Putative binding domain Glyco_hydro_16 PF00722.16 EAQ93379.1 - 1.3e-43 148.4 0.4 2.2e-43 147.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I_N PF02919.10 EAQ93380.1 - 6.5e-97 323.0 3.7 6.5e-97 323.0 2.6 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EAQ93380.1 - 1.1e-83 279.8 6.4 1.1e-83 279.8 4.4 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EAQ93380.1 - 9.4e-30 102.0 0.1 9.4e-30 102.0 0.0 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain PspB PF06667.7 EAQ93380.1 - 1.3 8.9 3.9 0.73 9.8 0.2 2.5 2 0 0 2 2 2 0 Phage shock protein B ATP-synt PF00231.14 EAQ93381.1 - 1.9e-71 240.8 0.6 2.1e-71 240.6 0.4 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S3_C PF00189.15 EAQ93381.1 - 0.0082 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain DUF4127 PF13552.1 EAQ93381.1 - 0.042 12.2 0.2 0.13 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) Amino_oxidase PF01593.19 EAQ93382.1 - 7.6e-90 302.1 0.0 1.4e-89 301.2 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EAQ93382.1 - 2e-10 40.6 0.0 4.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EAQ93382.1 - 4.2e-08 33.1 0.1 9.8e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EAQ93382.1 - 4.3e-06 26.9 2.3 1.6e-05 25.0 1.6 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAQ93382.1 - 0.00062 20.0 2.1 0.0013 19.0 1.4 1.6 1 0 0 1 1 1 1 HMG-box domain DAO PF01266.19 EAQ93382.1 - 0.063 12.1 3.4 0.077 11.8 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Sec1 PF00995.18 EAQ93383.1 - 1.8e-139 465.9 0.0 2.1e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UPF0167 PF03691.9 EAQ93383.1 - 0.041 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) UQ_con PF00179.21 EAQ93384.1 - 1.7e-13 50.1 0.0 1.8e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ93384.1 - 0.017 14.8 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase PF00069.20 EAQ93385.1 - 2e-70 236.9 0.0 2.5e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93385.1 - 7.9e-33 113.6 0.0 1.2e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ93385.1 - 6.7e-06 25.2 0.0 9.4e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAQ93385.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EAQ93385.1 - 0.0016 17.8 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EAQ93385.1 - 0.075 12.7 0.5 1 9.0 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family PFL PF02901.10 EAQ93386.1 - 0.32 9.3 1.9 0.44 8.9 1.3 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase PV-1 PF06637.6 EAQ93386.1 - 0.63 8.5 3.2 4.8 5.6 0.0 2.2 2 0 0 2 2 2 0 PV-1 protein (PLVAP) DUF4407 PF14362.1 EAQ93386.1 - 1.6 7.5 4.0 2.4 7.0 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) tRNA-synt_His PF13393.1 EAQ93387.1 - 1.1e-33 116.6 0.0 2.3e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EAQ93387.1 - 9e-13 47.9 0.0 1.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EAQ93387.1 - 8.4e-10 38.4 0.0 2.3e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EAQ93387.1 - 0.0035 16.1 0.0 0.24 10.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) ABC_membrane PF00664.18 EAQ93388.1 - 1.9e-60 204.6 27.1 2.4e-33 115.7 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAQ93388.1 - 1.2e-44 151.9 0.0 3.1e-31 108.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAQ93388.1 - 1.6e-09 37.3 1.3 0.0051 16.0 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ93388.1 - 1.5e-08 34.9 0.0 0.016 15.2 0.1 3.5 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EAQ93388.1 - 6.3e-05 23.0 0.6 0.00066 19.7 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.4 EAQ93388.1 - 0.00013 20.7 0.1 0.0044 15.6 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EAQ93388.1 - 0.00017 21.4 1.3 0.18 11.7 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EAQ93388.1 - 0.0028 17.2 0.1 0.49 9.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EAQ93388.1 - 0.0059 16.7 0.3 0.26 11.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAQ93388.1 - 0.017 14.2 0.0 0.055 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAQ93388.1 - 0.022 15.5 0.0 0.071 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAQ93388.1 - 0.024 14.1 0.3 0.081 12.4 0.2 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EAQ93388.1 - 0.062 12.7 0.2 0.68 9.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 EAQ93388.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain dCMP_cyt_deam_1 PF00383.17 EAQ93389.1 - 3.3e-16 58.7 0.0 4.1e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EAQ93389.1 - 8.5e-10 38.7 0.6 9.9e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EAQ93389.1 - 0.0011 18.4 0.4 0.76 9.1 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases FYVE PF01363.16 EAQ93390.1 - 2.2e-21 75.5 0.7 2.2e-21 75.5 0.5 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EAQ93390.1 - 1.1e-07 31.5 5.6 1.1e-07 31.5 3.9 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EAQ93390.1 - 0.00036 20.1 2.8 0.00036 20.1 1.9 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EAQ93390.1 - 0.0016 17.8 2.3 0.042 13.3 0.3 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-rbx1 PF12678.2 EAQ93390.1 - 0.011 15.8 5.1 0.011 15.8 3.5 3.7 3 0 0 3 3 3 0 RING-H2 zinc finger FYVE_2 PF02318.11 EAQ93390.1 - 0.013 15.4 1.1 0.013 15.4 0.7 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 EAQ93390.1 - 0.021 14.8 4.8 0.021 14.8 3.4 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 EAQ93390.1 - 1.4 8.2 6.2 0.27 10.5 0.7 2.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase zf-piccolo PF05715.8 EAQ93390.1 - 2.7 8.0 9.3 2.7 8.0 3.2 3.0 3 0 0 3 3 3 0 Piccolo Zn-finger zinc_ribbon_2 PF13240.1 EAQ93390.1 - 5.7 6.5 7.9 5 6.7 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain SH3BGR PF04908.10 EAQ93391.1 - 0.00011 22.1 3.0 0.00024 21.0 0.0 3.0 3 1 0 3 3 3 1 SH3-binding, glutamic acid-rich protein CENP-B_dimeris PF09026.5 EAQ93391.1 - 1.3 9.3 23.0 3.3 7.9 16.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NAM-associated PF14303.1 EAQ93392.1 - 4.6 7.5 7.5 3.6 7.8 4.4 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Spore_YtfJ PF09579.5 EAQ93393.1 - 0.17 11.7 1.4 0.33 10.8 0.3 1.8 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) AAA PF00004.24 EAQ93394.1 - 2.4e-49 166.9 0.0 1.8e-43 147.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAQ93394.1 - 8.6e-05 22.0 0.0 0.0005 19.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAQ93394.1 - 0.00013 22.7 0.0 0.00045 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAQ93394.1 - 0.0002 20.4 0.0 0.00054 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EAQ93394.1 - 0.00045 20.2 0.5 0.021 14.7 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAQ93394.1 - 0.00057 20.0 0.0 0.0038 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EAQ93394.1 - 0.00068 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 EAQ93394.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EAQ93394.1 - 0.0032 17.3 0.0 0.0076 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EAQ93394.1 - 0.0034 17.1 0.0 0.017 14.8 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EAQ93394.1 - 0.0064 16.6 0.0 0.033 14.3 0.0 2.3 3 0 0 3 3 1 1 RNA helicase TIP49 PF06068.8 EAQ93394.1 - 0.01 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 EAQ93394.1 - 0.017 14.8 0.0 0.071 12.8 0.0 2.2 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EAQ93394.1 - 0.024 13.7 0.1 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EAQ93394.1 - 0.029 13.4 0.0 0.073 12.1 0.0 1.6 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EAQ93394.1 - 0.035 13.3 0.0 0.075 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EAQ93394.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ93394.1 - 0.064 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ93394.1 - 0.077 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAQ93394.1 - 0.093 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAQ93394.1 - 0.093 11.6 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EAQ93394.1 - 0.13 11.6 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EAQ93394.1 - 0.16 11.5 0.2 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EAQ93394.1 - 0.31 9.6 0.0 0.49 8.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Abhydro_lipase PF04083.11 EAQ93395.1 - 2e-19 68.7 0.0 5.3e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EAQ93395.1 - 9.8e-05 22.3 5.9 9.8e-05 22.3 4.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAQ93395.1 - 0.00025 20.8 0.0 0.00049 19.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1237 PF06824.6 EAQ93396.1 - 1.9e-185 616.4 0.3 3.1e-185 615.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) AICARFT_IMPCHas PF01808.13 EAQ93397.1 - 5.4e-111 370.6 0.0 7.3e-111 370.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EAQ93397.1 - 2.8e-23 81.6 0.0 5.7e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain RRM_6 PF14259.1 EAQ93398.1 - 6.4e-13 48.4 0.1 4.1e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ93398.1 - 8e-13 47.8 0.0 7.8e-05 22.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93398.1 - 5.4e-05 22.9 0.0 0.00034 20.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 EAQ93398.1 - 1.7 8.3 4.9 0.93 9.2 0.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Proteasom_Rpn13 PF04683.8 EAQ93399.1 - 6e-26 90.3 0.0 9.4e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Anp1 PF03452.9 EAQ93400.1 - 2.1e-109 364.8 0.0 2.5e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EAQ93400.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 UQ_con PF00179.21 EAQ93401.1 - 1.4e-30 105.5 0.0 1.6e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ93401.1 - 0.0036 17.0 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAQ93401.1 - 0.052 13.4 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain Cgr1 PF03879.9 EAQ93403.1 - 1.3e-35 121.8 24.9 1.9e-35 121.3 17.2 1.1 1 0 0 1 1 1 1 Cgr1 family ABC_tran_2 PF12848.2 EAQ93403.1 - 0.46 10.3 16.0 0.73 9.7 11.1 1.3 1 0 0 1 1 1 0 ABC transporter Pal1 PF08316.6 EAQ93403.1 - 1.2 9.5 4.1 11 6.4 0.9 2.3 2 0 0 2 2 2 0 Pal1 cell morphology protein RR_TM4-6 PF06459.7 EAQ93403.1 - 2.6 7.8 11.9 2.9 7.7 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PRP1_N PF06424.7 EAQ93403.1 - 6.5 7.0 11.4 0.62 10.3 4.8 1.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Med9 PF07544.8 EAQ93404.1 - 0.0025 17.5 1.2 0.0082 15.8 0.8 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 KxDL PF10241.4 EAQ93404.1 - 0.18 11.7 1.4 4.2 7.3 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF3818 PF12825.2 EAQ93405.1 - 3.2e-134 446.9 1.0 4.4e-134 446.4 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EAQ93405.1 - 3e-37 127.3 0.7 5.9e-37 126.3 0.5 1.4 1 0 0 1 1 1 1 PX-associated Myc_N PF01056.13 EAQ93405.1 - 0.038 13.1 1.5 0.061 12.4 1.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Tegument_dsDNA PF12818.2 EAQ93405.1 - 0.14 11.0 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 dsDNA viral tegument protein FAD_binding_2 PF00890.19 EAQ93406.1 - 1.1e-123 413.1 4.5 1.4e-123 412.8 3.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EAQ93406.1 - 4.3e-48 162.4 0.9 6.2e-48 161.8 0.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EAQ93406.1 - 3.5e-07 30.3 0.4 0.0049 16.7 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAQ93406.1 - 4.1e-05 22.7 0.3 0.028 13.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EAQ93406.1 - 0.00011 21.2 1.2 0.038 12.8 1.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EAQ93406.1 - 0.0019 17.2 0.6 0.0047 15.8 0.2 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAQ93406.1 - 0.0038 16.3 0.1 0.0038 16.3 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain DUF3405 PF11885.3 EAQ93408.1 - 1.6e-198 659.9 1.6 1.6e-198 659.9 1.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) Apt1 PF10351.4 EAQ93408.1 - 0.084 11.7 0.5 0.12 11.1 0.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EMP24_GP25L PF01105.19 EAQ93409.1 - 2.7e-45 154.3 0.0 3.1e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 EAQ93409.1 - 0.0099 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SpoU_methylase PF00588.14 EAQ93409.1 - 0.098 12.5 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family Arf PF00025.16 EAQ93410.1 - 1.1e-78 262.4 0.2 1.3e-78 262.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAQ93410.1 - 1.9e-13 49.9 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EAQ93410.1 - 5.9e-13 48.5 0.0 6.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EAQ93410.1 - 1.6e-12 46.8 1.2 5.2e-09 35.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EAQ93410.1 - 3.4e-11 42.7 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAQ93410.1 - 1.4e-08 35.2 0.0 2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAQ93410.1 - 9.8e-06 25.5 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EAQ93410.1 - 0.0024 16.9 0.1 0.0056 15.7 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EAQ93410.1 - 0.016 14.6 0.1 0.11 11.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EAQ93410.1 - 0.04 13.7 0.1 0.083 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EAQ93411.1 - 1.3e-45 155.4 0.0 3.2e-44 150.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EAQ93411.1 - 2.4e-24 85.0 0.1 8.5e-24 83.2 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EAQ93411.1 - 2.8e-19 69.6 0.1 3.2e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAQ93411.1 - 5.1e-12 45.7 0.0 6.5e-09 35.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ93411.1 - 6.9e-09 35.9 13.5 0.007 16.3 0.0 5.1 4 2 0 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 EAQ93411.1 - 8.7e-09 35.6 1.7 0.0074 16.4 0.0 3.6 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EAQ93411.1 - 5.9e-07 29.1 0.4 0.00023 20.6 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EAQ93411.1 - 7.3e-07 29.1 0.0 0.052 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EAQ93411.1 - 9.2e-06 25.4 0.2 0.19 11.3 0.1 3.0 2 1 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 EAQ93411.1 - 1.4e-05 24.8 7.5 0.059 13.0 0.2 4.4 3 2 0 3 3 3 2 Archaeal ATPase AAA_17 PF13207.1 EAQ93411.1 - 2.7e-05 24.9 3.3 0.0072 17.1 0.0 3.9 4 1 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 EAQ93411.1 - 9.5e-05 21.8 0.1 0.2 11.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EAQ93411.1 - 0.00018 21.8 6.2 0.065 13.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain MobB PF03205.9 EAQ93411.1 - 0.00034 20.3 0.1 0.07 12.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EAQ93411.1 - 0.00071 18.7 0.1 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EAQ93411.1 - 0.0011 19.0 0.0 0.39 10.9 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EAQ93411.1 - 0.0014 18.6 1.1 3.4 7.5 0.0 3.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 EAQ93411.1 - 0.0015 18.3 1.1 4.2 7.1 0.0 4.1 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EAQ93411.1 - 0.0019 17.9 0.2 0.91 9.3 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain AAA_33 PF13671.1 EAQ93411.1 - 0.0029 17.4 0.0 4.3 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EAQ93411.1 - 0.0042 16.5 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EAQ93411.1 - 0.008 16.4 0.6 1.7 8.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EAQ93411.1 - 0.011 15.2 0.0 0.21 11.0 0.0 3.0 2 2 1 3 3 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 EAQ93411.1 - 0.014 13.9 0.0 1.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 EAQ93411.1 - 0.022 14.1 0.9 3.9 6.8 0.1 2.9 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EAQ93411.1 - 0.027 14.0 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EAQ93411.1 - 0.039 13.0 0.1 2.4 7.2 0.0 3.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EAQ93411.1 - 0.048 13.1 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EAQ93411.1 - 0.052 14.0 0.1 4.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein APG6 PF04111.7 EAQ93411.1 - 0.056 12.4 6.3 0.089 11.8 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PduV-EutP PF10662.4 EAQ93411.1 - 0.1 12.0 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Seryl_tRNA_N PF02403.17 EAQ93411.1 - 0.11 12.5 13.5 0.31 11.0 8.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 EAQ93411.1 - 0.82 9.5 13.6 1.6 8.5 9.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EAQ93411.1 - 1.1 7.0 4.9 1.6 6.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OEP PF02321.13 EAQ93411.1 - 2.6 7.6 10.3 6.4 6.3 7.2 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein DUF724 PF05266.9 EAQ93411.1 - 4.2 6.9 10.8 7.5 6.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 EAQ93411.1 - 9.7 5.7 12.4 24 4.4 8.6 1.6 1 0 0 1 1 1 0 IncA protein Sld5 PF05916.6 EAQ93412.1 - 1.8e-14 53.9 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sulfate_transp PF00916.15 EAQ93413.1 - 3.4e-32 111.5 3.9 8.4e-32 110.2 0.9 2.7 2 1 0 2 2 2 1 Sulfate transporter family Kinesin PF00225.18 EAQ93415.1 - 2.6e-95 318.9 0.1 4.5e-95 318.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain OmpH PF03938.9 EAQ93415.1 - 0.12 12.3 4.5 0.096 12.6 0.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spore_coat_CotO PF14153.1 EAQ93415.1 - 0.31 10.4 5.9 0.24 10.8 2.5 2.0 2 0 0 2 2 2 0 Spore coat protein CotO p450 PF00067.17 EAQ93417.1 - 1.8e-68 231.1 0.0 2.3e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.15 EAQ93418.1 - 3.5e-178 593.2 6.1 4.7e-178 592.8 4.2 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ93418.1 - 9.9e-20 70.3 0.2 1.5e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EAQ93418.1 - 0.013 14.6 0.7 0.14 11.2 0.1 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.6 EAQ93418.1 - 0.037 12.9 0.1 0.091 11.6 0.0 1.6 2 0 0 2 2 2 0 StbA protein TPP_enzyme_N PF02776.13 EAQ93418.1 - 0.061 12.8 0.2 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peptidase_C6 PF00851.13 EAQ93418.1 - 0.064 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Helper component proteinase Peroxin-13_N PF04088.8 EAQ93419.1 - 1.9e-58 196.8 0.0 2.8e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EAQ93419.1 - 3.2e-07 29.7 0.0 5.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAQ93419.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAQ93419.1 - 2.3e-05 23.6 0.0 4.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain TFIIA PF03153.8 EAQ93420.1 - 9.9e-97 325.1 1.8 1.3e-96 324.7 1.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 EAQ93421.1 - 2e-25 87.6 17.3 1.7e-06 27.7 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EAQ93421.1 - 4.3e-06 26.5 0.2 0.00019 21.1 0.1 2.4 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EAQ93421.1 - 0.026 14.0 0.0 0.55 9.7 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.2 EAQ93421.1 - 0.36 10.5 5.1 2.9 7.5 0.0 3.8 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Kelch_4 PF13418.1 EAQ93422.1 - 3.6e-28 97.0 7.4 1.4e-08 34.3 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EAQ93422.1 - 5.7e-23 80.4 5.4 3.1e-06 26.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EAQ93422.1 - 1.4e-22 78.8 2.9 7.2e-05 22.7 0.0 5.2 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EAQ93422.1 - 3.5e-21 74.4 1.0 4.6e-05 22.8 0.1 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EAQ93422.1 - 5.5e-21 74.1 11.9 9.2e-08 32.0 0.1 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EAQ93422.1 - 1.3e-18 65.8 3.8 4.5e-05 23.0 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EAQ93422.1 - 1e-08 35.1 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rax2 PF12768.2 EAQ93422.1 - 0.16 11.1 0.0 0.45 9.6 0.0 1.8 1 1 1 2 2 2 0 Cortical protein marker for cell polarity zf-H2C2_2 PF13465.1 EAQ93423.1 - 8.7e-05 22.6 6.4 0.0067 16.6 0.5 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EAQ93423.1 - 0.029 14.5 0.2 0.029 14.5 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EAQ93423.1 - 0.047 14.0 0.5 0.047 14.0 0.4 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ93423.1 - 0.055 13.8 17.2 0.097 13.0 1.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3254 PF11630.3 EAQ93424.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) HIG_1_N PF04588.8 EAQ93425.1 - 1e-06 28.3 3.1 2.5e-06 27.0 2.1 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Kelch_4 PF13418.1 EAQ93426.1 - 2e-44 149.1 18.4 2.2e-09 36.9 0.4 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EAQ93426.1 - 1.4e-42 142.9 24.8 5.9e-10 39.0 0.2 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EAQ93426.1 - 1.2e-38 130.4 14.8 1.6e-06 27.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EAQ93426.1 - 1.7e-37 126.7 15.2 4.1e-08 32.6 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EAQ93426.1 - 3.5e-33 112.3 15.5 1.3e-06 28.3 0.1 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EAQ93426.1 - 8.5e-32 107.7 14.4 5e-09 35.5 0.4 6.4 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.1 EAQ93426.1 - 2.4 8.5 15.4 44 4.5 0.7 5.8 5 0 0 5 5 5 0 PQQ-like domain Dus PF01207.12 EAQ93427.1 - 6.5e-31 107.3 0.0 4e-21 75.1 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EAQ93427.1 - 0.00082 19.0 5.7 0.037 13.7 0.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pro_isomerase PF00160.16 EAQ93428.1 - 1.7e-24 86.8 0.1 1.9e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BNIP3 PF06553.7 EAQ93429.1 - 0.13 11.6 0.1 0.27 10.6 0.0 1.5 2 0 0 2 2 2 0 BNIP3 RRM_1 PF00076.17 EAQ93430.1 - 1.6e-58 194.2 4.2 1.1e-13 50.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93430.1 - 2.1e-52 174.9 2.1 3.6e-13 49.2 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93430.1 - 8.5e-26 89.5 0.8 5.2e-06 26.2 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAQ93430.1 - 0.0042 16.8 0.1 9.5 6.0 0.0 4.0 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM PF05172.8 EAQ93430.1 - 0.13 11.9 0.0 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Dynein_light PF01221.13 EAQ93431.1 - 4.4e-12 45.8 1.4 6.2e-12 45.3 1.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4007 PF13182.1 EAQ93431.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) WSK PF03832.8 EAQ93431.1 - 0.28 10.5 1.9 0.68 9.3 1.3 1.6 1 0 0 1 1 1 0 WSK motif DUF1777 PF08648.7 EAQ93432.1 - 0.0017 18.0 19.5 0.0017 18.0 13.5 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Methyltransf_16 PF10294.4 EAQ93435.1 - 1.6e-20 73.2 0.0 2.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EAQ93435.1 - 0.0028 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ93435.1 - 0.0055 17.2 0.0 0.021 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Dehyd-heme_bind PF09098.5 EAQ93435.1 - 0.021 14.2 0.1 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding MTS PF05175.9 EAQ93435.1 - 0.022 14.1 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EAQ93435.1 - 0.077 13.0 0.1 1.3 9.1 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain HCV_NS5a_1b PF08301.8 EAQ93437.1 - 0.023 15.0 0.1 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b HSP70 PF00012.15 EAQ93440.1 - 1.9e-230 765.9 5.8 2.1e-230 765.7 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAQ93440.1 - 5e-17 61.4 0.7 3.7e-16 58.6 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EAQ93440.1 - 0.00076 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EAQ93440.1 - 0.092 12.5 1.0 15 5.4 0.0 3.6 3 1 0 3 3 3 0 Cell division protein FtsA DUF406 PF04175.7 EAQ93440.1 - 0.13 12.7 0.8 11 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF406) IF4E PF01652.13 EAQ93441.1 - 7e-60 201.3 0.1 8.6e-60 201.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 EAQ93442.1 - 1.6e-70 237.5 0.0 2.4e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ93442.1 - 9.7e-11 42.4 0.2 1.9e-10 41.5 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 EAQ93443.1 - 1.3e-28 98.7 2.0 1.6e-28 98.4 1.4 1.1 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.13 EAQ93445.1 - 7e-59 198.9 0.1 1.4e-58 198.0 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EAQ93445.1 - 1.8e-24 86.2 0.0 2.7e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EAQ93445.1 - 5e-13 48.7 12.0 5e-13 48.7 8.3 2.1 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.11 EAQ93445.1 - 3.2 7.6 11.3 0.35 10.7 4.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_M3_N PF08439.5 EAQ93446.1 - 0.075 13.0 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Oligopeptidase F Med15 PF09606.5 EAQ93447.1 - 0.0063 14.7 20.1 0.01 14.0 13.9 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AIF_C PF14721.1 EAQ93447.1 - 0.053 13.7 2.0 0.12 12.6 1.4 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PAT1 PF09770.4 EAQ93447.1 - 0.086 11.0 18.6 0.12 10.5 12.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 EAQ93447.1 - 0.13 12.0 0.8 0.26 11.1 0.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2000 PF09391.5 EAQ93447.1 - 0.17 11.5 0.5 0.34 10.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) FAM91_C PF14648.1 EAQ93447.1 - 0.3 9.8 1.4 0.6 8.8 1.0 1.5 1 0 0 1 1 1 0 FAM91 C-terminus Hid1 PF12722.2 EAQ93447.1 - 1.1 6.9 5.3 1.4 6.5 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FimP PF09766.4 EAQ93447.1 - 1.5 7.8 17.0 2.4 7.1 11.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein RNA_pol_Rpc4 PF05132.9 EAQ93447.1 - 1.6 8.7 9.8 0.15 12.0 3.5 1.7 2 0 0 2 2 1 0 RNA polymerase III RPC4 Pex14_N PF04695.8 EAQ93447.1 - 2.4 8.2 16.8 4.8 7.2 9.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4557 PF15101.1 EAQ93447.1 - 4 7.2 15.6 10 5.9 10.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ndc1_Nup PF09531.5 EAQ93447.1 - 6.8 4.9 6.4 11 4.3 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.3 EAQ93447.1 - 7.6 5.8 12.1 16 4.8 8.4 1.4 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 EAQ93447.1 - 9.1 5.9 18.4 0.81 9.3 8.9 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Cyclin_N PF00134.18 EAQ93448.1 - 3e-39 133.4 1.4 5.7e-39 132.5 0.1 2.2 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAQ93448.1 - 4.9e-11 42.5 1.3 2e-10 40.6 0.1 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain PAT1 PF09770.4 EAQ93448.1 - 1.6 6.9 9.6 2.3 6.3 6.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rad4 PF03835.10 EAQ93450.1 - 4.4e-15 55.3 6.9 7.6e-15 54.5 4.8 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EAQ93450.1 - 1.5e-14 54.1 2.5 3.6e-14 52.9 1.7 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.1 EAQ93450.1 - 0.28 10.6 4.7 1.2 8.5 0.6 2.6 1 1 1 2 2 2 0 Cold-inducible protein YdjO WD40 PF00400.27 EAQ93452.1 - 9.7e-09 34.7 14.4 0.0027 17.5 0.0 9.2 10 0 0 10 10 10 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EAQ93452.1 - 9.8e-08 31.7 1.1 4.6e-07 29.5 0.3 2.2 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 EAQ93452.1 - 0.0004 20.5 0.5 2.6 8.4 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 EAQ93452.1 - 0.0066 15.9 0.1 0.75 9.4 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat NAPRTase PF04095.11 EAQ93453.1 - 3.7e-53 180.3 0.3 1.6e-52 178.2 0.2 1.8 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family ATP-synt_G PF04718.10 EAQ93456.1 - 2.3e-27 95.6 1.2 3.2e-26 91.9 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit TPP_enzyme_N PF02776.13 EAQ93456.1 - 0.44 10.0 5.0 0.89 9.0 3.5 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF2580 PF10824.3 EAQ93456.1 - 0.88 9.9 10.4 0.47 10.8 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) zf-H2C2_2 PF13465.1 EAQ93457.1 - 0.008 16.4 0.6 0.008 16.4 0.4 2.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ93457.1 - 1.4 9.3 4.2 35 5.0 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ93457.1 - 3.1 8.3 7.9 0.73 10.2 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADH_N PF08240.7 EAQ93459.1 - 1e-26 92.8 3.3 2.1e-26 91.7 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ93459.1 - 1e-15 57.4 0.1 1.6e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Collagen PF01391.13 EAQ93459.1 - 0.11 12.0 1.1 0.19 11.2 0.8 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) S1-like PF14444.1 EAQ93459.1 - 0.12 12.1 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 S1-like Bap31 PF05529.7 EAQ93461.1 - 1.3e-66 223.7 2.2 1.5e-66 223.5 1.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF192 PF02643.10 EAQ93461.1 - 0.0043 16.7 0.1 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Anoctamin PF04547.7 EAQ93461.1 - 0.45 9.1 4.8 0.53 8.8 3.3 1.4 1 1 0 1 1 1 0 Calcium-activated chloride channel DivIC PF04977.10 EAQ93461.1 - 2.3 7.7 7.6 2.8 7.4 0.4 3.4 3 1 0 4 4 4 0 Septum formation initiator DUF1479 PF07350.7 EAQ93462.1 - 9.5e-156 518.4 0.0 1.2e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EAQ93462.1 - 0.0056 16.7 0.0 0.066 13.2 0.0 2.3 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 4F5 PF04419.9 EAQ93463.1 - 0.00048 20.8 4.8 0.00064 20.3 3.3 1.2 1 0 0 1 1 1 1 4F5 protein family DIOX_N PF14226.1 EAQ93464.1 - 2e-14 54.1 0.0 7.9e-07 29.6 0.0 2.9 3 0 0 3 3 3 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAQ93464.1 - 1.4e-06 28.5 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EAQ93465.1 - 7.1e-08 32.0 9.4 0.0001 22.0 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat MRJP PF03022.11 EAQ93465.1 - 0.18 10.9 0.6 5.5 6.1 0.0 2.7 3 0 0 3 3 3 0 Major royal jelly protein RNA_pol_N PF01194.12 EAQ93466.1 - 8.1e-29 99.4 1.2 1.1e-28 99.0 0.8 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EAQ93466.1 - 0.052 13.6 0.5 0.076 13.1 0.4 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) RNA_pol_Rpb1_1 PF04997.7 EAQ93469.1 - 3.6e-112 374.9 0.0 9.7e-112 373.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EAQ93469.1 - 2.6e-99 331.9 0.3 5.4e-99 330.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EAQ93469.1 - 4e-69 231.8 0.1 1.3e-68 230.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EAQ93469.1 - 1.9e-58 197.3 4.1 4.4e-58 196.1 2.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EAQ93469.1 - 1.4e-45 154.8 0.0 5.4e-45 152.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EAQ93469.1 - 1.8e-44 150.7 8.0 4.1e-44 149.5 5.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EAQ93469.1 - 4.3e-38 129.3 0.1 1e-37 128.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-C4pol PF14260.1 EAQ93469.1 - 0.032 14.2 0.8 0.076 13.0 0.6 1.6 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta RNA_pol_Rpb1_R PF05001.8 EAQ93469.1 - 0.23 11.6 194.5 0.033 14.2 7.7 13.7 8 2 7 16 16 16 0 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EAQ93470.1 - 4.1e-13 48.6 3.8 4e-05 23.3 0.2 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 EAQ93470.1 - 1.1e-05 25.2 0.0 0.022 14.4 0.0 3.3 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EAQ93470.1 - 0.1 12.0 0.1 0.35 10.3 0.1 2.0 1 1 1 2 2 2 0 PQQ-like domain Bromodomain PF00439.20 EAQ93473.1 - 7.4e-34 115.5 0.0 6.1e-17 61.3 0.1 2.4 2 0 0 2 2 2 2 Bromodomain FH2 PF02181.18 EAQ93473.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain RNA_pol_3_Rpc31 PF11705.3 EAQ93473.1 - 0.024 14.5 9.6 0.043 13.7 6.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 IFT57 PF10498.4 EAQ93473.1 - 0.19 10.4 2.9 0.3 9.8 2.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDC45 PF02724.9 EAQ93473.1 - 3.8 5.4 11.7 5.7 4.8 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CKS PF01111.14 EAQ93474.1 - 4.7e-19 67.9 0.1 7.3e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.10 EAQ93475.1 - 1.4e-124 415.7 0.0 1.7e-124 415.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.4 EAQ93476.1 - 1.1e-18 67.1 0.0 1.3e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 EAQ93477.1 - 4.5e-10 40.1 0.5 1e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Pal1 cell morphology protein CPSF_A PF03178.10 EAQ93478.1 - 7.9e-70 235.4 0.0 1.8e-69 234.3 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region LMBR1 PF04791.11 EAQ93479.1 - 7.6e-15 54.4 3.3 7.6e-15 54.4 2.3 2.2 1 1 0 2 2 2 1 LMBR1-like membrane protein DUF2207 PF09972.4 EAQ93479.1 - 9.4 4.6 7.3 7 5.1 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) UDG PF03167.14 EAQ93482.1 - 4.7e-24 84.5 0.2 8.8e-24 83.6 0.0 1.5 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF605 PF04652.11 EAQ93482.1 - 0.37 10.1 11.3 0.46 9.8 7.8 1.1 1 0 0 1 1 1 0 Vta1 like UDPGP PF01704.13 EAQ93483.1 - 3.6e-53 180.5 0.0 5.1e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.1 EAQ93483.1 - 0.024 14.2 0.1 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NTP_transf_3 PF12804.2 EAQ93483.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Mpv17_PMP22 PF04117.7 EAQ93484.1 - 6.9e-26 89.6 3.0 1.2e-25 88.8 2.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ubiquitin PF00240.18 EAQ93485.1 - 8.7e-18 63.4 0.1 1.3e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EAQ93485.1 - 2.4e-09 36.7 0.3 2.9e-08 33.3 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EAQ93485.1 - 0.0014 18.2 0.4 0.0022 17.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EAQ93485.1 - 0.0072 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAQ93485.1 - 0.031 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Glyco_hydro_18 PF00704.23 EAQ93486.1 - 3.9e-51 174.5 0.0 1.7e-50 172.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Myosin_head PF00063.16 EAQ93487.1 - 6.8e-233 774.6 2.1 1e-232 774.0 1.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EAQ93487.1 - 7.9e-39 133.0 0.0 2.1e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EAQ93487.1 - 1.3e-12 46.9 0.1 2.6e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAQ93487.1 - 2.1e-12 46.4 0.1 5.3e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAQ93487.1 - 2.6e-09 36.4 0.0 1.1e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 EAQ93487.1 - 0.0015 18.0 9.7 0.04 13.5 1.7 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EAQ93487.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain SH3_3 PF08239.6 EAQ93487.1 - 0.0078 16.3 0.3 0.019 15.1 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Zeta_toxin PF06414.7 EAQ93487.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EAQ93487.1 - 0.037 13.3 0.1 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EAQ93487.1 - 0.071 13.9 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAQ93487.1 - 0.1 12.2 0.1 0.27 10.8 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EAQ93487.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain FAD_binding_8 PF08022.7 EAQ93488.1 - 2.7e-23 81.8 0.0 5.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EAQ93488.1 - 4.1e-22 78.7 0.0 6.6e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EAQ93488.1 - 1.2e-16 60.8 9.1 1.2e-16 60.8 6.3 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EAQ93488.1 - 8.1e-05 22.6 0.0 0.00024 21.1 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain LrgA PF03788.9 EAQ93488.1 - 0.018 14.7 0.1 0.018 14.7 0.1 1.8 2 0 0 2 2 2 0 LrgA family NAD_binding_1 PF00175.16 EAQ93488.1 - 0.1 13.1 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Pex2_Pex12 PF04757.9 EAQ93489.1 - 5.4e-41 140.4 0.0 9e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EAQ93489.1 - 0.00019 21.2 4.3 0.00041 20.1 3.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAQ93489.1 - 0.13 11.9 2.4 0.15 11.8 0.2 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Na_trans_assoc PF06512.8 EAQ93489.1 - 6.3 6.6 6.7 0.37 10.7 0.5 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated IBN_N PF03810.14 EAQ93490.1 - 8.4e-16 57.6 0.8 1.6e-14 53.5 0.2 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EAQ93490.1 - 7.4e-05 22.6 4.7 0.0002 21.3 0.1 3.7 4 1 0 5 5 5 1 Exportin 1-like protein DNA_ligase_A_N PF04675.9 EAQ93490.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA ligase N terminus TPR_12 PF13424.1 EAQ93491.1 - 9.8e-72 236.9 0.3 2.6e-16 59.3 0.0 4.8 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ93491.1 - 1.2e-68 225.3 0.0 1.2e-11 44.1 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ93491.1 - 1.7e-18 64.8 1.4 0.0013 18.3 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAQ93491.1 - 2.5e-11 42.6 1.9 0.64 10.0 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EAQ93491.1 - 5.6e-11 41.7 0.1 7.2 7.3 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAQ93491.1 - 7.2e-11 41.4 0.8 0.19 12.0 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ93491.1 - 4.2e-10 39.1 0.4 0.061 12.9 0.0 4.8 1 1 4 5 5 5 5 TPR repeat NB-ARC PF00931.17 EAQ93491.1 - 1.5e-09 37.1 0.0 2.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 EAQ93491.1 - 6.9e-09 34.9 0.0 0.55 9.9 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAQ93491.1 - 1e-08 35.0 4.4 16 6.4 0.0 7.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAQ93491.1 - 1.1e-08 35.4 0.0 0.26 12.0 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAQ93491.1 - 1.3e-06 28.6 0.3 0.55 10.6 0.0 5.1 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAQ93491.1 - 2.9e-05 23.5 0.1 2.8 7.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.7 EAQ93491.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Apc3 PF12895.2 EAQ93491.1 - 0.00033 20.7 0.0 0.96 9.6 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.2 EAQ93491.1 - 0.0046 16.9 0.0 17 5.4 0.0 3.6 1 1 2 3 3 3 0 Tetratrico peptide repeat AAA_25 PF13481.1 EAQ93491.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain TPR_3 PF07720.7 EAQ93491.1 - 0.006 16.3 0.0 23 4.8 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4074 PF13293.1 EAQ93491.1 - 0.0085 16.2 0.0 18 5.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4074) PPR PF01535.15 EAQ93491.1 - 0.0089 15.9 1.1 37 4.6 0.1 4.7 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.1 EAQ93491.1 - 0.012 16.0 3.8 20 5.8 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Rab5-bind PF09311.6 EAQ93491.1 - 0.015 15.1 0.1 7.2 6.4 0.1 3.2 1 1 2 3 3 3 0 Rabaptin-like protein Granin PF01271.12 EAQ93491.1 - 0.028 13.1 0.6 1.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Granin (chromogranin or secretogranin) AAA_22 PF13401.1 EAQ93491.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1_like PF12832.2 EAQ93493.1 - 8.4e-22 76.7 0.4 2.7e-21 75.1 0.3 1.9 1 0 0 1 1 1 1 MFS_1 like family Cytochrom_B558a PF05038.8 EAQ93493.1 - 0.0052 16.4 1.4 0.0054 16.3 0.1 1.6 2 0 0 2 2 2 1 Cytochrome Cytochrome b558 alpha-subunit Pribosyltran PF00156.22 EAQ93496.1 - 6.2e-15 55.0 0.0 1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EAQ93496.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 EAQ93497.1 - 4.5e-135 450.8 0.0 5.4e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Acetyltransf_1 PF00583.19 EAQ93500.1 - 3e-13 49.6 0.0 7.2e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ93500.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 EAQ93502.1 - 7e-08 31.6 0.2 1.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nup54 PF13874.1 EAQ93502.1 - 0.03 14.0 2.1 0.032 13.8 0.4 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Zn_clus PF00172.13 EAQ93502.1 - 0.067 13.1 1.8 0.15 11.9 1.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP-utilisers_N PF05524.8 EAQ93502.1 - 0.12 12.2 0.2 0.45 10.3 0.3 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal adh_short PF00106.20 EAQ93504.1 - 7.4e-28 97.5 7.1 1.3e-27 96.7 4.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ93504.1 - 2.3e-26 93.0 0.0 3.1e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ93504.1 - 4.1e-15 55.8 3.9 7.6e-15 55.0 2.7 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ93504.1 - 0.065 12.6 0.4 0.18 11.2 0.3 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Globin PF00042.17 EAQ93507.1 - 1.2e-10 41.6 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EAQ93507.1 - 2.3e-06 28.1 0.0 6.6e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EAQ93507.1 - 2.4e-06 27.6 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 EAQ93507.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 EAQ93507.1 - 0.058 13.2 0.9 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DUF1720 PF08226.6 EAQ93510.1 - 9.7 6.3 13.6 2.7e+02 1.7 9.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EAQ93511.1 - 0.041 13.2 2.8 1.3 8.5 0.6 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EAQ93511.1 - 0.13 12.2 1.9 2.4 8.2 0.8 2.8 2 0 0 2 2 2 0 EF-hand domain Nop14 PF04147.7 EAQ93511.1 - 0.73 7.6 12.3 1.3 6.9 8.5 1.4 1 0 0 1 1 1 0 Nop14-like family Vps53_N PF04100.7 EAQ93512.1 - 5.9e-75 252.4 0.9 9.1e-74 248.5 0.6 2.0 1 1 0 1 1 1 1 Vps53-like, N-terminal Spc7 PF08317.6 EAQ93512.1 - 0.024 13.3 0.9 0.041 12.5 0.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Rbsn PF11464.3 EAQ93512.1 - 0.029 13.9 0.9 0.12 11.9 0.6 2.1 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Uds1 PF15456.1 EAQ93512.1 - 0.31 11.0 6.9 5.3 7.0 4.2 2.4 1 1 1 2 2 2 0 Up-regulated During Septation NPR2 PF06218.6 EAQ93513.1 - 2.3e-89 300.0 0.0 2.9e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.20 EAQ93514.1 - 6e-77 258.6 0.0 9.2e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CybS PF05328.7 EAQ93515.1 - 6e-52 174.7 0.0 7.4e-52 174.4 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EAQ93515.1 - 0.0081 15.9 0.3 0.061 13.1 0.2 2.0 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2Fe-2S_Ferredox PF11591.3 EAQ93515.1 - 8.7 6.0 8.6 21 4.8 5.9 1.6 1 1 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Zn_clus PF00172.13 EAQ93516.1 - 7.2e-06 25.8 11.6 1.1e-05 25.1 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAQ93516.1 - 3.3e-05 22.9 0.1 5.1e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3419 PF11899.3 EAQ93517.1 - 1.7e-152 507.5 0.0 2.2e-152 507.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EAQ93517.1 - 1.2e-07 31.6 0.0 1.7e-06 27.8 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAQ93517.1 - 1.7e-07 31.2 0.0 1.9e-05 24.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ93517.1 - 5.9e-07 29.8 0.0 3.2e-06 27.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAQ93517.1 - 3e-06 26.9 0.0 3.2e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAQ93517.1 - 4.7e-05 22.6 0.0 0.096 11.7 0.0 2.5 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EAQ93517.1 - 5.4e-05 23.5 0.0 0.036 14.5 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAQ93517.1 - 0.0018 18.6 0.0 0.0044 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAQ93517.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ada3 PF10198.4 EAQ93518.1 - 1.7e-48 163.7 0.0 5.7e-48 161.9 0.0 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EAQ93519.1 - 8.5e-12 44.7 6.7 1.8e-11 43.6 4.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAQ93519.1 - 5.6e-07 29.4 7.4 1.1e-06 28.6 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAQ93519.1 - 7.7e-07 28.7 5.2 1.2e-06 28.0 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAQ93519.1 - 1.6e-06 28.1 1.5 8e-06 25.8 1.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAQ93519.1 - 1.2e-05 24.8 6.7 2e-05 24.1 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAQ93519.1 - 1.7e-05 24.4 4.0 2.8e-05 23.7 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAQ93519.1 - 0.0023 17.7 0.8 0.006 16.3 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EAQ93519.1 - 0.019 14.6 1.5 0.019 14.6 1.0 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAQ93519.1 - 0.063 13.1 7.0 0.13 12.1 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAQ93519.1 - 0.21 11.2 3.2 0.36 10.4 2.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EAQ93519.1 - 0.32 10.9 4.2 3.2 7.7 2.8 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EAQ93519.1 - 0.76 9.8 4.4 1.3 9.0 3.1 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EAQ93519.1 - 0.97 9.1 3.7 1.7 8.3 2.5 1.4 1 0 0 1 1 1 0 PHD-finger DUF726 PF05277.7 EAQ93520.1 - 1e-113 379.7 0.5 1.7e-113 379.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EAQ93520.1 - 9.4e-07 28.9 0.3 6.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EAQ93520.1 - 2.8e-05 24.4 0.0 8.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EAQ93520.1 - 0.00073 19.3 0.0 0.0024 17.6 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF605 PF04652.11 EAQ93520.1 - 0.00092 18.7 20.9 0.00092 18.7 14.5 1.6 2 0 0 2 2 2 1 Vta1 like Cutinase PF01083.17 EAQ93520.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Noc2 PF03715.8 EAQ93521.1 - 2.5e-110 368.0 0.1 7.1e-110 366.5 0.0 1.8 2 0 0 2 2 2 1 Noc2p family DUF876 PF05936.7 EAQ93521.1 - 0.007 14.8 0.0 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF876) DUF4095 PF13338.1 EAQ93521.1 - 0.019 15.1 0.4 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) DUF2404 PF10296.4 EAQ93522.1 - 0.001 19.1 0.0 0.0045 17.1 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) AT_hook PF02178.14 EAQ93523.1 - 0.0029 17.0 12.0 0.23 11.2 0.3 4.7 4 0 0 4 4 4 2 AT hook motif PTCB-BRCT PF12738.2 EAQ93523.1 - 0.019 14.8 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF155 PF02582.9 EAQ93524.1 - 1.1e-57 194.7 0.1 1.8e-57 194.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.12 EAQ93524.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Gly-zipper_OmpA PF13436.1 EAQ93524.1 - 5.1 6.7 7.3 13 5.4 5.0 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain ArsA_ATPase PF02374.10 EAQ93526.1 - 7.8e-25 87.5 0.1 1.1e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EAQ93526.1 - 7e-12 45.1 0.1 1.2e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNase_P_p30 PF01876.11 EAQ93526.1 - 1.1e-08 34.3 0.0 2.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit p30 Fer4_NifH PF00142.13 EAQ93526.1 - 6.7e-06 25.4 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 EAQ93526.1 - 6.1e-05 23.0 0.1 0.00015 21.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EAQ93526.1 - 0.00083 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EAQ93526.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain MipZ PF09140.6 EAQ93526.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ IstB_IS21 PF01695.12 EAQ93526.1 - 0.025 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EAQ93526.1 - 0.033 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 EAQ93526.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 EAQ93526.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EAQ93526.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2201_N PF13203.1 EAQ93526.1 - 2.2 7.3 6.1 3 6.9 4.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain GFA PF04828.9 EAQ93528.1 - 1.7e-06 27.8 1.2 4.6e-06 26.4 0.8 1.7 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Kisspeptin PF15152.1 EAQ93528.1 - 0.089 13.4 0.0 0.15 12.7 0.0 1.4 1 1 0 1 1 1 0 Kisspeptin Cys_rich_CWC PF14375.1 EAQ93528.1 - 0.11 12.4 3.9 0.17 11.7 2.7 1.4 1 0 0 1 1 1 0 Cysteine-rich CWC HET PF06985.6 EAQ93529.1 - 4.3e-33 114.3 0.1 7.2e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acyl_transf_3 PF01757.17 EAQ93530.1 - 8e-31 107.1 14.6 1.4e-30 106.2 10.1 1.4 1 1 0 1 1 1 1 Acyltransferase family Gastrin PF00918.12 EAQ93531.1 - 0.12 13.1 1.3 0.15 12.9 0.9 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Ctr PF04145.10 EAQ93531.1 - 0.21 11.6 0.5 0.24 11.4 0.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF1049 PF06305.6 EAQ93531.1 - 1.7 8.1 9.1 1.8 8.1 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) PNPOx_C PF10590.4 EAQ93532.1 - 0.077 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Med8 PF10232.4 EAQ93533.1 - 4.1e-26 91.8 10.9 4.8e-25 88.3 7.6 2.2 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 REC114-like PF15165.1 EAQ93533.1 - 0.0092 15.7 0.1 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like BAF1_ABF1 PF04684.8 EAQ93533.1 - 0.012 14.4 0.3 0.018 13.8 0.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BTV_NS2 PF04514.7 EAQ93533.1 - 0.03 13.1 5.2 0.041 12.7 3.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nucleo_P87 PF07267.6 EAQ93533.1 - 0.037 12.7 1.6 0.04 12.6 1.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NIL PF09383.5 EAQ93533.1 - 0.079 12.5 0.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 NIL domain Orthopox_35kD PF02250.10 EAQ93533.1 - 0.095 11.9 0.2 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 35kD major secreted virus protein FlxA PF14282.1 EAQ93533.1 - 0.32 10.9 0.1 0.32 10.9 0.0 2.4 2 1 0 2 2 2 0 FlxA-like protein CENP-B_dimeris PF09026.5 EAQ93533.1 - 1.5 9.1 15.9 1.2 9.4 6.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myc_N PF01056.13 EAQ93533.1 - 1.8 7.6 6.8 3.8 6.5 4.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region VID27 PF08553.5 EAQ93533.1 - 1.9 6.6 6.9 2.6 6.1 4.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DNA_pol_phi PF04931.8 EAQ93533.1 - 2.2 5.9 13.1 3.3 5.3 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF972 PF06156.8 EAQ93533.1 - 2.6 8.4 5.9 2.9 8.2 1.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) GRP PF07172.6 EAQ93533.1 - 4.1 7.9 8.3 0.78 10.2 2.2 2.0 2 0 0 2 2 2 0 Glycine rich protein family Sulfatase PF00884.18 EAQ93534.1 - 1.9e-52 178.4 0.0 2.5e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EAQ93534.1 - 5.7e-24 83.6 2.3 2.5e-23 81.6 0.4 2.4 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EAQ93534.1 - 3.2e-10 39.8 0.2 4.4e-09 36.1 0.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EAQ93534.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily PQ-loop PF04193.9 EAQ93535.1 - 3.7e-23 80.8 4.7 4.5e-13 48.5 2.0 2.6 2 0 0 2 2 2 2 PQ loop repeat MtrF PF09472.5 EAQ93535.1 - 0.22 10.8 4.2 2.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Ric8 PF10165.4 EAQ93536.1 - 1e-143 479.3 0.0 1.3e-143 479.0 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Chromo PF00385.19 EAQ93536.1 - 8.7e-13 47.7 0.1 1.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Baculo_PP31 PF05311.6 EAQ93536.1 - 1.4 8.1 5.6 0.13 11.4 0.6 1.6 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Rif1_N PF12231.3 EAQ93537.1 - 5.3e-146 486.3 1.7 7.2e-146 485.9 1.2 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.15 EAQ93538.1 - 9.1e-23 80.8 0.0 1.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.11 EAQ93539.1 - 1.1e-193 643.5 0.0 1.2e-193 643.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family UBA_4 PF14555.1 EAQ93540.1 - 0.085 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain GRA6 PF05084.8 EAQ93540.1 - 1.1 8.6 7.6 2.1 7.8 2.7 1.9 1 1 1 2 2 2 0 Granule antigen protein (GRA6) E1-E2_ATPase PF00122.15 EAQ93541.1 - 9.1e-54 181.9 0.1 9.1e-54 181.9 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAQ93541.1 - 1.2e-45 156.5 2.9 1.2e-45 156.5 2.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EAQ93541.1 - 3.7e-43 145.4 0.4 3.6e-11 43.0 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EAQ93541.1 - 1.1e-12 48.4 0.1 3.3e-12 46.9 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAQ93541.1 - 0.00015 21.4 2.3 0.00054 19.6 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 EAQ93541.1 - 0.057 12.9 2.3 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) PCI PF01399.22 EAQ93542.1 - 5.1e-05 23.5 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EAQ93543.1 - 3.9e-09 36.6 0.0 2.4e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain Ribosomal_L31e PF01198.14 EAQ93544.1 - 5.9e-35 118.7 1.4 7.3e-35 118.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 EAQ93545.1 - 1.3e-48 164.0 0.0 1.5e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAQ93545.1 - 7.8e-06 25.6 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAQ93545.1 - 0.001 18.9 0.1 0.0011 18.8 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EAQ93545.1 - 0.0046 16.6 0.1 0.0068 16.0 0.0 1.4 1 1 0 1 1 1 1 UEV domain Pkinase PF00069.20 EAQ93546.1 - 4.8e-54 183.2 0.0 6.2e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93546.1 - 6.8e-24 84.3 0.0 9.8e-24 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAQ93546.1 - 7.8e-08 31.6 0.0 1.6e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EAQ93546.1 - 0.0045 16.0 0.0 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAQ93546.1 - 0.076 12.7 6.0 0.5 10.0 0.0 3.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.2 EAQ93548.1 - 9.1e-10 38.1 0.2 2e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAQ93548.1 - 1.9e-07 30.5 0.0 5.3e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain ABC_tran PF00005.22 EAQ93550.1 - 7e-49 165.6 0.0 1.7e-28 99.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAQ93550.1 - 4.5e-27 95.1 31.2 7.3e-17 61.6 8.5 3.4 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EAQ93550.1 - 8.2e-10 38.2 0.0 0.00031 20.0 0.0 4.1 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EAQ93550.1 - 4.7e-06 26.1 0.0 0.01 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAQ93550.1 - 0.00014 21.3 0.9 0.61 9.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EAQ93550.1 - 0.00041 19.3 0.0 0.2 10.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EAQ93550.1 - 0.00065 19.7 2.6 0.067 13.1 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EAQ93550.1 - 0.0011 19.3 1.9 0.036 14.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EAQ93550.1 - 0.007 15.5 0.1 3.2 6.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EAQ93550.1 - 0.012 15.4 2.3 0.43 10.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_21 PF13304.1 EAQ93550.1 - 0.014 15.3 0.3 5.7 6.8 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_30 PF13604.1 EAQ93550.1 - 0.015 14.8 0.6 3.6 7.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 EAQ93550.1 - 0.023 14.6 0.0 5.8 6.9 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EAQ93550.1 - 0.028 14.5 0.1 24 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EAQ93550.1 - 0.034 14.0 1.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EAQ93550.1 - 0.054 14.0 0.7 6 7.4 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 EAQ93550.1 - 0.097 12.0 0.1 6.6 6.1 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 EAQ93550.1 - 0.098 11.6 0.1 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EAQ93551.1 - 2.4e-26 90.5 9.1 1e-07 31.5 0.0 7.5 7 1 1 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EAQ93551.1 - 0.00064 19.4 0.1 0.33 10.6 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EAQ93551.1 - 0.015 14.8 0.5 0.015 14.8 0.4 2.5 2 0 0 2 2 2 0 HIRA B motif Amidase PF01425.16 EAQ93552.1 - 4.1e-79 266.5 0.0 4.8e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Methyltransf_11 PF08241.7 EAQ93553.1 - 0.013 15.9 0.1 0.099 13.1 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain DUF1776 PF08643.5 EAQ93554.1 - 2.3e-115 384.8 0.0 3.1e-115 384.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EAQ93555.1 - 2.4e-34 117.6 2.1 2.4e-33 114.4 0.6 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EAQ93555.1 - 5.3e-23 81.9 0.3 1.6e-22 80.3 0.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAQ93555.1 - 8e-13 48.6 0.6 1.7e-10 41.1 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAQ93555.1 - 6.4e-11 42.6 0.0 8.7e-08 32.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 EAQ93555.1 - 9.1e-07 28.6 0.0 3.3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAO PF01266.19 EAQ93555.1 - 4.2e-06 25.9 2.0 0.21 10.4 0.0 3.8 3 1 1 4 4 4 3 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.1 EAQ93555.1 - 1.4e-05 26.0 0.1 6.1e-05 23.9 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EAQ93555.1 - 1.8e-05 24.9 0.6 0.0053 16.9 0.0 3.1 3 1 0 3 3 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EAQ93555.1 - 0.00011 21.4 0.1 0.0008 18.5 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EAQ93555.1 - 0.00035 20.5 0.8 0.12 12.4 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EAQ93555.1 - 0.002 17.0 7.2 0.74 8.6 0.2 3.9 2 2 2 4 4 4 2 Glucose inhibited division protein A Shikimate_DH PF01488.15 EAQ93555.1 - 0.0091 16.0 2.0 3.5 7.7 0.0 2.9 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EAQ93555.1 - 0.0099 15.4 5.1 0.47 10.0 0.9 3.7 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 EAQ93555.1 - 0.029 13.3 0.2 0.96 8.2 0.0 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EAQ93555.1 - 0.052 12.1 0.4 0.6 8.6 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_10 PF13460.1 EAQ93555.1 - 0.065 13.2 3.3 0.94 9.4 0.3 3.0 2 1 1 3 3 3 0 NADH(P)-binding HI0933_like PF03486.9 EAQ93555.1 - 0.074 11.5 3.6 2.4 6.5 0.1 4.0 3 2 1 5 5 5 0 HI0933-like protein TrkA_N PF02254.13 EAQ93555.1 - 0.11 12.5 3.6 0.19 11.7 0.1 3.0 4 0 0 4 4 3 0 TrkA-N domain DUF1254 PF06863.7 EAQ93555.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) 2-Hacid_dh_C PF02826.14 EAQ93555.1 - 0.19 10.8 1.9 1.4 8.0 0.1 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EAQ93555.1 - 1 8.1 11.2 0.084 11.7 0.2 3.8 4 1 1 5 5 5 0 FAD binding domain DUF1772 PF08592.6 EAQ93556.1 - 2.4e-05 24.0 0.1 3.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MFS_1 PF07690.11 EAQ93557.1 - 4.5e-19 68.3 33.6 4.6e-13 48.6 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ93557.1 - 4.8e-17 61.6 22.1 3.6e-15 55.5 2.4 2.8 1 1 1 3 3 3 3 Sugar (and other) transporter DUF1345 PF07077.6 EAQ93557.1 - 0.096 12.1 2.1 0.29 10.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF948 PF06103.6 EAQ93559.1 - 2.6 7.9 4.6 49 3.8 0.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 EAQ93559.1 - 4.7 6.6 14.0 0.21 11.0 3.4 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 Borrelia_P83 PF05262.6 EAQ93559.1 - 8.4 4.5 23.2 12 3.9 16.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3453 PF11935.3 EAQ93560.1 - 5.2e-73 245.3 0.0 7.9e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 EAQ93562.1 - 2.4e-28 99.0 5.7 2.4e-28 99.0 3.9 3.7 2 2 0 3 3 3 1 Sds3-like DUF2407_C PF13373.1 EAQ93562.1 - 1 9.3 3.9 1.1 9.1 0.8 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain RRM_1 PF00076.17 EAQ93563.1 - 2.3e-10 39.9 0.1 9.3e-08 31.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93563.1 - 3.3e-09 36.4 0.0 0.00035 20.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93563.1 - 5.5e-07 29.4 0.1 8.7e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EAQ93563.1 - 1.2 7.4 20.5 2 6.8 14.2 1.3 1 0 0 1 1 1 0 Daxx Family Tubulin_C PF03953.12 EAQ93564.1 - 0.00058 19.8 0.0 0.00082 19.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Glyco_hydro_16 PF00722.16 EAQ93565.1 - 4.7e-18 65.1 0.5 7.9e-18 64.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EAQ93565.1 - 4.3e-05 21.8 2.2 0.039 12.1 0.0 2.3 3 0 0 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) Zn_clus PF00172.13 EAQ93566.1 - 1.3e-06 28.1 9.1 3.7e-06 26.7 6.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.4 EAQ93567.1 - 6.4e-20 71.4 0.1 6.4e-20 71.4 0.0 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 EAQ93567.1 - 1.2 8.9 5.9 1.5 8.5 4.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.19 EAQ93572.1 - 0.0003 20.3 7.2 0.00055 19.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CAP_GLY PF01302.20 EAQ93573.1 - 1.7e-20 72.4 0.1 3.3e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EAQ93573.1 - 3.1e-17 61.7 5.3 3.7e-06 26.4 0.1 4.8 5 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ93573.1 - 8.3e-09 35.0 3.5 0.00095 18.8 0.2 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EAQ93573.1 - 1.9e-08 33.1 3.2 6.1 7.2 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 EAQ93573.1 - 2.2e-08 33.3 4.6 1.7 8.9 0.0 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 EAQ93573.1 - 8.6e-06 25.1 7.7 8 7.1 0.0 6.6 7 0 0 7 7 7 1 Leucine rich repeat MaoC_dehydratas PF01575.14 EAQ93574.1 - 2.6e-23 81.7 0.0 4.6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EAQ93574.1 - 1.2e-08 34.8 0.0 1.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Menin PF05053.8 EAQ93575.1 - 0.88 7.6 16.6 1.2 7.1 11.5 1.2 1 0 0 1 1 1 0 Menin WD40 PF00400.27 EAQ93576.1 - 4.1e-20 70.8 7.4 2.5e-07 30.2 0.1 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 EAQ93577.1 - 8.4e-26 89.7 0.4 9.2e-26 89.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 EAQ93577.1 - 0.0094 16.0 1.1 0.013 15.6 0.7 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) DUF4111 PF13427.1 EAQ93577.1 - 0.054 13.3 0.1 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Drf_GBD PF06371.8 EAQ93577.1 - 0.072 12.4 0.2 0.082 12.2 0.1 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Gag_p17 PF00540.13 EAQ93577.1 - 0.072 12.8 0.3 0.084 12.6 0.2 1.1 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Chon_Sulph_att PF06566.6 EAQ93578.1 - 0.52 9.8 4.2 0.68 9.5 2.9 1.2 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain SinI PF08671.5 EAQ93579.1 - 0.034 13.5 1.0 0.1 12.0 0.7 1.8 1 0 0 1 1 1 0 Anti-repressor SinI Nop14 PF04147.7 EAQ93579.1 - 0.12 10.2 12.0 0.16 9.8 8.3 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1656 PF07869.7 EAQ93579.1 - 0.12 12.1 1.4 0.22 11.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) CENP-B_dimeris PF09026.5 EAQ93579.1 - 0.18 12.0 10.6 0.36 11.0 7.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EAQ93579.1 - 1.2 8.6 8.8 2 7.9 6.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EAQ93579.1 - 1.4 7.3 11.2 1.8 6.9 7.8 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EAQ93579.1 - 3.1 6.9 8.3 4.3 6.5 5.8 1.1 1 0 0 1 1 1 0 NOA36 protein Acetyltransf_3 PF13302.1 EAQ93581.1 - 2.4e-22 79.6 0.0 2.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAQ93581.1 - 0.04 13.8 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L18ae PF01775.12 EAQ93582.1 - 5.8e-59 197.4 0.5 7.3e-59 197.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 EAQ93583.1 - 3.4e-13 49.8 0.0 1.8e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EAQ93583.1 - 0.036 13.7 0.1 0.098 12.3 0.0 1.7 1 0 0 1 1 1 0 TPR repeat BTB PF00651.26 EAQ93584.1 - 9.9e-10 38.3 0.2 4e-09 36.4 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.10 EAQ93584.1 - 0.1 12.6 0.0 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Abhydrolase_5 PF12695.2 EAQ93585.1 - 2e-06 27.5 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAQ93585.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LRR_4 PF12799.2 EAQ93586.1 - 1.3e-42 142.7 20.1 1.3e-11 43.8 0.5 6.5 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ93586.1 - 4.1e-30 103.3 65.5 6.8e-08 32.1 0.5 4.8 2 1 7 9 9 9 7 Leucine rich repeat LRR_7 PF13504.1 EAQ93586.1 - 1.9e-10 39.2 16.1 2.3 8.7 0.0 8.8 9 0 0 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 EAQ93586.1 - 2.5e-10 38.9 24.0 0.16 12.0 0.2 9.8 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 EAQ93586.1 - 7.7e-10 37.8 19.3 0.13 12.4 0.2 9.7 5 3 6 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 EAQ93586.1 - 2.4e-09 37.0 7.5 0.00025 20.6 2.0 3.9 1 1 3 4 4 4 3 Leucine-rich repeat Aldo_ket_red PF00248.16 EAQ93587.1 - 1e-49 168.9 0.0 1.2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_28 PF13518.1 EAQ93587.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Yos1 PF08571.5 EAQ93588.1 - 3.5e-09 36.6 0.0 3.6e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.24 EAQ93589.1 - 6.3e-62 209.1 2.0 9.2e-62 208.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAQ93589.1 - 4.3e-30 105.1 4.7 2.8e-23 82.7 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EAQ93589.1 - 0.0068 15.7 1.4 2.4 7.3 0.5 3.4 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Borrelia_P83 PF05262.6 EAQ93589.1 - 0.29 9.3 14.3 0.44 8.7 9.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec61_beta PF03911.11 EAQ93590.1 - 7.8e-21 73.6 1.5 1e-20 73.2 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family NIF PF03031.13 EAQ93591.1 - 1.5e-42 144.9 0.0 2.1e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.10 EAQ93592.1 - 6.3e-97 324.0 0.8 6.8e-96 320.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EAQ93592.1 - 8.5e-15 55.2 0.0 2.1e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAQ93592.1 - 0.0037 17.2 0.0 0.023 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EAQ93592.1 - 0.015 14.3 0.0 0.061 12.3 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EAQ93592.1 - 0.037 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EAQ93592.1 - 0.05 13.9 1.2 0.35 11.1 0.9 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAQ93592.1 - 0.063 14.0 0.0 0.37 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAQ93592.1 - 0.071 13.0 0.4 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EAQ93592.1 - 0.09 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EAQ93592.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PP2C PF00481.16 EAQ93593.1 - 5.9e-56 189.6 0.0 1.1e-55 188.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EAQ93593.1 - 2.7e-47 157.7 45.2 1.2e-06 27.9 0.3 13.1 4 2 9 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAQ93593.1 - 5.1e-43 144.6 45.3 8.7e-09 35.0 0.5 8.7 6 2 0 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EAQ93593.1 - 3e-24 81.3 43.6 0.74 10.0 0.0 18.9 19 1 0 19 19 19 9 Leucine Rich Repeat Guanylate_cyc PF00211.15 EAQ93593.1 - 8.5e-24 83.9 0.0 1.9e-23 82.7 0.0 1.5 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.6 EAQ93593.1 - 8.4e-21 73.0 2.0 2.2e-20 71.7 1.4 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 EAQ93593.1 - 1.7e-12 45.3 50.4 0.61 10.5 0.0 17.3 19 0 0 19 19 19 2 Leucine rich repeat RA PF00788.18 EAQ93593.1 - 7.2e-11 42.4 0.0 2e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 EAQ93593.1 - 9.3e-06 25.2 37.2 10 6.5 0.2 14.2 15 1 1 16 16 16 1 Leucine Rich repeat LRR_9 PF14580.1 EAQ93593.1 - 0.00038 20.0 8.4 1.6 8.2 0.0 3.9 2 1 1 3 3 3 3 Leucine-rich repeat RTC4 PF14474.1 EAQ93595.1 - 3.2e-31 107.8 0.0 5.3e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 EAQ93596.1 - 8.1e-30 103.8 0.4 1.6e-27 96.3 0.3 2.3 1 1 0 1 1 1 1 Dynamitin ThiS PF02597.15 EAQ93596.1 - 6.8e-05 23.2 2.5 9e-05 22.8 0.0 2.6 3 1 0 3 3 3 1 ThiS family Perilipin PF03036.11 EAQ93596.1 - 0.018 13.9 1.1 0.043 12.6 0.0 2.0 2 0 0 2 2 2 0 Perilipin family BLOC1_2 PF10046.4 EAQ93596.1 - 0.061 13.4 1.3 57 3.9 0.4 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.14 EAQ93596.1 - 0.62 9.5 4.9 1.1 8.7 0.4 2.9 3 0 0 3 3 3 0 GrpE DivIC PF04977.10 EAQ93596.1 - 0.68 9.4 11.5 0.33 10.4 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF1192 PF06698.6 EAQ93596.1 - 0.73 9.6 16.1 0.66 9.8 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FlgN PF05130.7 EAQ93596.1 - 3.1 8.0 17.8 0.077 13.2 1.9 3.1 2 1 1 3 3 3 0 FlgN protein CorA PF01544.13 EAQ93596.1 - 3.3 6.6 7.4 0.6 9.0 0.8 2.3 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2203 PF09969.4 EAQ93596.1 - 4.9 7.3 6.6 46 4.2 0.2 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 EAQ93596.1 - 6.5 6.3 6.3 3.1 7.3 0.2 2.6 3 0 0 3 3 3 0 IncA protein Hemerythrin PF01814.18 EAQ93596.1 - 7.3 6.7 8.3 7.2 6.7 0.2 3.2 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain COG4 PF08318.7 EAQ93597.1 - 1.6e-92 309.7 0.0 2.6e-92 309.1 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Dynamin_N PF00350.18 EAQ93597.1 - 6.3e-30 104.2 0.0 1.7e-29 102.7 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAQ93597.1 - 1.3e-11 43.8 0.0 2.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 EAQ93597.1 - 0.001 19.5 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAQ93597.1 - 0.0013 18.6 0.0 0.024 14.5 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EAQ93597.1 - 0.021 15.1 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Macoilin PF09726.4 EAQ93597.1 - 0.088 11.0 0.6 0.15 10.3 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Ras PF00071.17 EAQ93597.1 - 0.12 11.8 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 Ras family Pex19 PF04614.7 EAQ93597.1 - 1 8.9 3.7 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Pex19 protein family E1-E2_ATPase PF00122.15 EAQ93598.1 - 4.1e-72 241.9 0.0 6.5e-72 241.2 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAQ93598.1 - 1.5e-41 141.9 0.1 3.5e-41 140.7 0.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAQ93598.1 - 2.7e-29 103.1 0.0 1.1e-28 101.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAQ93598.1 - 4.2e-20 70.9 0.5 8.7e-20 69.9 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAQ93598.1 - 1.8e-12 47.8 0.0 4.8e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAQ93598.1 - 4.6e-07 29.7 0.0 9.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAQ93598.1 - 3.4e-05 23.5 1.1 6e-05 22.7 0.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SpoVAE PF14097.1 EAQ93599.1 - 0.042 13.2 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Rad21_Rec8_N PF04825.8 EAQ93600.1 - 4.4e-35 119.9 0.0 8.1e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EAQ93600.1 - 9.6e-08 31.0 0.9 1.5e-07 30.4 0.1 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EAQ93600.1 - 0.00083 19.0 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein Peptidase_S9 PF00326.16 EAQ93601.1 - 5.3e-46 156.5 0.0 1.8e-45 154.7 0.0 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAQ93601.1 - 4e-07 29.9 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NuA4 PF09340.5 EAQ93602.1 - 1e-25 89.1 0.0 1.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 YPEB PF14620.1 EAQ93602.1 - 0.093 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation PspB PF06667.7 EAQ93602.1 - 0.11 12.3 0.1 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B Med3 PF11593.3 EAQ93602.1 - 2.2 7.4 7.1 0.12 11.6 0.8 1.8 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal HemX PF04375.9 EAQ93602.1 - 5.2 5.5 6.5 1.5 7.2 0.0 2.2 2 1 0 2 2 2 0 HemX PWI PF01480.12 EAQ93603.1 - 9.4e-29 99.3 0.0 1.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.13 EAQ93605.1 - 2.3e-51 174.3 0.0 2.7e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.7 EAQ93606.1 - 6.9e-58 194.3 0.0 7.9e-58 194.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_1 PF00190.17 EAQ93606.1 - 3.6e-06 26.4 0.0 6.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EAQ93606.1 - 5.4e-06 25.8 0.0 8.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EAQ93606.1 - 0.0023 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 EAQ93606.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.7 EAQ93606.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein DZR PF12773.2 EAQ93606.1 - 0.44 10.4 5.2 1 9.2 3.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon TFIIA PF03153.8 EAQ93607.1 - 5.9 6.6 9.9 17 5.1 4.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 EAQ93608.1 - 1.6e-109 354.2 17.6 2.5e-14 52.5 0.1 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat DUF1258 PF06869.7 EAQ93608.1 - 3.8e-13 49.1 1.7 0.17 10.9 0.0 7.3 1 1 6 7 7 7 3 Protein of unknown function (DUF1258) NACHT PF05729.7 EAQ93608.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EAQ93608.1 - 1.7e-09 37.1 0.1 32 4.3 0.0 7.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EAQ93608.1 - 2.4e-07 30.8 0.3 2e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Germane PF10646.4 EAQ93608.1 - 4.7e-07 29.9 8.2 5.6 7.1 0.2 7.0 2 1 5 7 7 7 3 Sporulation and spore germination NYD-SP28_assoc PF14775.1 EAQ93608.1 - 0.00016 21.2 2.9 48 3.7 0.0 7.3 8 0 0 8 8 8 0 Sperm tail C-terminal domain IL32 PF15225.1 EAQ93608.1 - 0.00025 20.9 0.9 11 5.9 0.0 5.3 1 1 4 6 6 6 0 Interleukin 32 DUF815 PF05673.8 EAQ93608.1 - 0.022 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HARP PF07443.8 EAQ93608.1 - 0.047 13.0 0.0 84 2.6 0.0 3.8 3 0 0 3 3 3 0 HepA-related protein (HARP) NB-ARC PF00931.17 EAQ93608.1 - 0.051 12.4 0.0 0.11 11.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain SsgA PF04686.7 EAQ93608.1 - 0.057 13.1 2.3 6.9 6.4 0.1 3.0 2 1 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA DUF948 PF06103.6 EAQ93608.1 - 0.085 12.7 0.2 0.53 10.1 0.1 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KAP_NTPase PF07693.9 EAQ93608.1 - 0.11 11.4 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain Methyltransf_3 PF01596.12 EAQ93608.1 - 0.13 11.2 1.7 28 3.6 0.0 4.9 6 2 1 7 7 7 0 O-methyltransferase DUF1652 PF07865.6 EAQ93608.1 - 0.18 11.4 8.2 8.7 6.0 0.0 6.5 8 0 0 8 8 8 0 Protein of unknown function (DUF1652) EXS PF03124.9 EAQ93609.1 - 4.6e-98 328.4 5.3 5.2e-98 328.2 3.7 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 EAQ93610.1 - 8.1e-43 146.4 0.1 1e-42 146.1 0.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EAQ93610.1 - 3.9e-07 29.9 2.7 7.2e-07 29.1 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAQ93610.1 - 2.6e-05 23.9 1.7 4.5e-05 23.2 1.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAQ93610.1 - 3.4e-05 23.4 3.5 6.6e-05 22.4 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAQ93610.1 - 3.8e-05 23.4 2.3 6.7e-05 22.6 1.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAQ93610.1 - 9.3e-05 22.0 2.2 0.00017 21.2 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAQ93610.1 - 0.00017 21.1 2.6 0.00025 20.6 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAQ93610.1 - 0.0061 16.2 1.1 0.011 15.3 0.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-LYAR PF08790.6 EAQ93611.1 - 2.4e-08 33.4 0.3 5e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DUF1975 PF09318.5 EAQ93611.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) 3-PAP PF12578.3 EAQ93611.1 - 1.1 9.0 5.4 1 9.2 2.6 1.8 2 0 0 2 2 2 0 Myotubularin-associated protein Gastrin PF00918.12 EAQ93611.1 - 2.6 8.8 6.9 1.7 9.5 0.2 2.8 3 0 0 3 3 3 0 Gastrin/cholecystokinin family Abhydrolase_5 PF12695.2 EAQ93612.1 - 1.4e-23 83.2 0.0 2.1e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAQ93612.1 - 1.2e-19 71.1 0.1 1.6e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ93612.1 - 1.7e-08 34.3 0.1 0.00044 19.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.7 EAQ93612.1 - 4.9e-06 25.5 0.0 6.8e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.7 EAQ93612.1 - 3e-05 22.6 0.3 0.23 9.8 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EAQ93612.1 - 0.0016 17.9 0.0 0.83 9.0 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 EAQ93612.1 - 0.0017 17.7 0.0 0.044 13.0 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.8 EAQ93612.1 - 0.0023 17.4 0.0 0.0099 15.3 0.0 2.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EAQ93612.1 - 0.0032 17.0 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAQ93612.1 - 0.0042 16.9 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 EAQ93612.1 - 0.0052 16.5 0.0 0.057 13.1 0.0 2.4 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EAQ93612.1 - 0.031 13.4 0.0 0.089 12.0 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family R3H PF01424.17 EAQ93613.1 - 2.4e-14 52.7 0.0 6e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EAQ93613.1 - 0.0058 16.5 13.1 0.0058 16.5 9.0 14.0 13 2 0 13 13 13 6 NF-X1 type zinc finger PTPA PF03095.10 EAQ93615.1 - 2.2e-113 378.4 0.0 2.5e-113 378.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.16 EAQ93616.1 - 7.1e-14 52.2 0.0 1.3e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAQ93616.1 - 0.038 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF3042 PF11240.3 EAQ93616.1 - 0.17 11.6 0.9 0.48 10.2 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) NAD_kinase PF01513.16 EAQ93617.1 - 1.8e-69 233.7 0.0 2.5e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Homeobox PF00046.24 EAQ93618.1 - 6.3e-09 35.3 1.3 1.6e-08 34.0 0.9 1.7 1 0 0 1 1 1 1 Homeobox domain zf-GRF PF06839.7 EAQ93618.1 - 1.7e-07 31.0 3.2 3.4e-07 30.0 2.2 1.5 1 0 0 1 1 1 1 GRF zinc finger ELMO_CED12 PF04727.8 EAQ93619.1 - 1.6e-21 76.6 0.0 4.4e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 EAQ93619.1 - 6.3e-05 22.7 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) Amidase PF01425.16 EAQ93619.1 - 0.17 10.6 2.4 0.3 9.8 1.7 1.3 1 0 0 1 1 1 0 Amidase FAD_binding_4 PF01565.18 EAQ93620.1 - 7.7e-20 70.7 0.1 1.3e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain C2 PF00168.25 EAQ93621.1 - 1e-68 227.1 0.2 5.6e-20 70.9 0.0 5.5 5 0 0 5 5 5 5 C2 domain zf-CCCH PF00642.19 EAQ93622.1 - 7e-09 35.1 17.3 2.8e-07 30.0 1.5 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EAQ93622.1 - 5.1e-05 23.0 0.0 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAQ93622.1 - 0.002 17.6 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93622.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 EAQ93622.1 - 0.98 9.2 5.3 0.69 9.7 0.2 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Tachystatin_B PF11478.3 EAQ93622.1 - 6.5 6.5 10.5 0.27 10.9 1.3 2.7 2 1 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B Oxysterol_BP PF01237.13 EAQ93624.1 - 1.6e-59 201.2 0.3 2.9e-45 154.2 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein DUF3729 PF12526.3 EAQ93624.1 - 0.83 11.0 12.9 1.8 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Abhydrolase_6 PF12697.2 EAQ93625.1 - 0.0018 18.2 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAQ93625.1 - 0.0036 17.1 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EAQ93625.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ammonium_transp PF00909.16 EAQ93626.1 - 9.1e-112 373.4 24.4 1.1e-111 373.0 16.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2207 PF09972.4 EAQ93626.1 - 1.8 7.0 4.7 8.4 4.8 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CRT10 PF08728.5 EAQ93627.1 - 1.9e-19 69.1 0.0 2.1e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 CRT10 Nucleoplasmin PF03066.10 EAQ93627.1 - 0.083 12.4 5.2 0.24 10.9 0.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin Cellulase PF00150.13 EAQ93628.1 - 3.8e-11 42.7 0.0 1.3e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.19 EAQ93629.1 - 2.7e-06 26.6 8.1 5.7e-06 25.6 5.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EAQ93629.1 - 0.0031 16.4 1.6 0.0063 15.4 1.1 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor TauD PF02668.11 EAQ93631.1 - 1.6e-15 57.4 0.2 2.8e-13 50.1 0.1 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EAQ93631.1 - 0.04 12.8 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 CsiD ATG13 PF10033.4 EAQ93632.1 - 0.011 15.1 0.1 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 13 Exo_endo_phos PF03372.18 EAQ93636.1 - 2.5e-20 73.4 0.0 1.6e-19 70.8 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF3379 PF11859.3 EAQ93636.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Dicty_REP PF05086.7 EAQ93636.1 - 2.8 5.6 6.6 3.7 5.1 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.4 EAQ93636.1 - 3.8 5.6 6.4 4.4 5.4 4.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pcc1 PF09341.5 EAQ93639.1 - 1.8e-24 85.5 1.4 3.1e-24 84.8 1.0 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.1 EAQ93640.1 - 7.4e-44 149.1 0.0 1.5e-40 138.4 0.0 3.3 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EAQ93640.1 - 9.1e-17 60.8 0.0 1.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAQ93640.1 - 9.2e-07 28.4 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EAQ93640.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate SWIM PF04434.12 EAQ93641.1 - 0.0036 16.7 0.1 0.0067 15.8 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Sulfate_transp PF00916.15 EAQ93642.1 - 1.3e-70 237.6 11.1 2.3e-70 236.8 7.7 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAQ93642.1 - 4.6e-30 103.1 3.0 4.6e-30 103.1 2.0 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EAQ93642.1 - 9.9e-08 31.4 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EAQ93642.1 - 0.38 10.5 8.3 0.1 12.2 0.3 3.5 3 0 0 3 3 3 0 Stannin transmembrane RabGAP-TBC PF00566.13 EAQ93644.1 - 2.9e-34 118.4 0.0 1.3e-27 96.6 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain HlyIII PF03006.15 EAQ93645.1 - 4.6e-57 192.9 19.7 5.7e-57 192.6 13.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related FtsK_SpoIIIE PF01580.13 EAQ93645.1 - 0.12 11.8 1.4 0.4 10.1 1.0 1.9 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF373 PF04123.8 EAQ93645.1 - 1.2 8.0 5.8 1.9 7.3 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF883 PF05957.8 EAQ93645.1 - 6.5 7.2 8.4 31 5.0 0.4 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FimP PF09766.4 EAQ93646.1 - 2.3e-28 99.2 10.4 3e-28 98.9 7.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein TSC22 PF01166.13 EAQ93646.1 - 0.03 14.2 6.5 0.55 10.2 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 EAQ93646.1 - 0.082 12.7 10.3 0.48 10.2 3.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cortex-I_coil PF09304.5 EAQ93646.1 - 0.1 12.6 10.8 0.36 10.8 3.3 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil DivIC PF04977.10 EAQ93646.1 - 0.5 9.8 7.8 2.3 7.7 2.7 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EAQ93646.1 - 1.5 9.1 9.7 5.7 7.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EAQ93646.1 - 1.8 8.5 14.4 2.1 8.2 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EAQ93646.1 - 3.5 6.4 9.3 1.8 7.4 4.8 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EAQ93646.1 - 5.8 5.8 9.6 4.1 6.3 3.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 CorA PF01544.13 EAQ93646.1 - 8.1 5.3 9.2 6 5.8 4.5 2.0 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Glyco_trans_2_3 PF13632.1 EAQ93648.1 - 4e-17 62.5 0.5 4e-17 62.5 0.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 INTS5_N PF14837.1 EAQ93648.1 - 0.059 12.7 0.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DUF4066 PF13278.1 EAQ93649.1 - 2.1e-12 46.6 0.0 2.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ93649.1 - 8.6e-08 31.7 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family FKBP_C PF00254.23 EAQ93650.1 - 3.4e-31 107.1 0.0 7.8e-30 102.7 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Utp14 PF04615.8 EAQ93650.1 - 1.7 6.6 36.0 2 6.4 6.6 2.0 2 0 0 2 2 2 0 Utp14 protein CinA PF02464.12 EAQ93651.1 - 2.4e-34 118.0 8.6 5.8e-34 116.7 6.0 1.7 1 1 0 1 1 1 1 Competence-damaged protein Pkinase PF00069.20 EAQ93651.1 - 9.1e-22 77.4 0.0 4.4e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93651.1 - 4.4e-06 25.9 0.0 1.1e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase zf-UBR PF02207.15 EAQ93652.1 - 1.7e-18 66.1 15.0 3.8e-18 64.9 10.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EAQ93652.1 - 3.9e-06 26.4 0.2 1.6e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EAQ93652.1 - 0.00035 20.3 0.8 0.00035 20.3 0.6 4.3 4 0 0 4 4 4 1 Ring finger domain CAP_N PF01213.14 EAQ93652.1 - 4 6.6 4.3 7.2 5.7 3.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal UCR_UQCRX_QCR9 PF05365.7 EAQ93653.1 - 5.8e-26 89.8 2.5 6.8e-26 89.6 1.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EAQ93654.1 - 2e-15 56.0 4.2 3.9e-15 55.1 2.9 1.5 1 0 0 1 1 1 1 Mago binding POP1 PF06978.6 EAQ93654.1 - 0.37 10.4 5.3 0.57 9.8 3.7 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Nucleo_P87 PF07267.6 EAQ93654.1 - 0.95 8.0 5.9 1 7.9 4.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BCS1_N PF08740.6 EAQ93655.1 - 1.3e-44 152.0 0.0 1.9e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EAQ93655.1 - 4.9e-21 75.3 0.0 7.3e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAQ93655.1 - 1.5e-05 24.1 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAQ93655.1 - 2.2e-05 25.2 0.0 5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAQ93655.1 - 2.4e-05 24.4 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAQ93655.1 - 9.4e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAQ93655.1 - 0.00017 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EAQ93655.1 - 0.00045 19.6 0.0 0.001 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAQ93655.1 - 0.00056 19.6 0.1 0.0042 16.8 0.1 2.5 1 1 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EAQ93655.1 - 0.0019 17.1 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EAQ93655.1 - 0.0025 17.6 0.0 0.0088 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EAQ93655.1 - 0.0096 15.5 0.3 0.027 14.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EAQ93655.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAQ93655.1 - 0.014 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAQ93655.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.1 EAQ93655.1 - 0.016 15.1 0.1 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 EAQ93655.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EAQ93655.1 - 0.036 14.2 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EAQ93655.1 - 0.039 14.2 0.0 0.094 13.0 0.0 1.6 2 0 0 2 2 1 0 ABC transporter Zeta_toxin PF06414.7 EAQ93655.1 - 0.039 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Miro PF08477.8 EAQ93655.1 - 0.042 14.3 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 EAQ93655.1 - 0.052 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EAQ93655.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 EAQ93655.1 - 0.069 11.8 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EAQ93655.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAQ93655.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EAQ93655.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Tim44 PF04280.10 EAQ93656.1 - 7.2e-34 116.8 0.0 2e-33 115.4 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain APO_RNA-bind PF05634.6 EAQ93656.1 - 0.12 11.5 0.5 0.24 10.5 0.4 1.4 1 0 0 1 1 1 0 APO RNA-binding DUF1768 PF08719.6 EAQ93657.1 - 1e-56 191.0 0.0 1.4e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ABC_tran PF00005.22 EAQ93658.1 - 2.3e-32 112.1 0.0 4.5e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EAQ93658.1 - 1e-12 48.0 8.9 1e-12 48.0 6.1 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EAQ93658.1 - 4.6e-06 26.0 0.0 3.8e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAQ93658.1 - 1.5e-05 25.1 0.0 0.0079 16.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain PAM2 PF07145.10 EAQ93658.1 - 0.00024 20.3 0.3 0.0005 19.3 0.2 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_17 PF13207.1 EAQ93658.1 - 0.0016 19.2 0.0 0.0039 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAQ93658.1 - 0.0028 16.8 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EAQ93658.1 - 0.0079 15.3 0.1 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 EAQ93658.1 - 0.015 15.6 0.2 0.04 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EAQ93658.1 - 0.017 15.0 0.3 0.12 12.2 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EAQ93658.1 - 0.032 13.7 0.2 0.082 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EAQ93658.1 - 0.058 12.3 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 EAQ93658.1 - 0.11 12.4 1.1 0.55 10.1 0.3 2.3 2 1 0 2 2 1 0 AAA ATPase domain AAA PF00004.24 EAQ93658.1 - 0.11 12.6 0.3 0.79 9.9 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AsmA_1 PF13109.1 EAQ93658.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region adh_short PF00106.20 EAQ93659.1 - 2.6e-18 66.4 7.2 2.6e-18 66.4 5.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ93659.1 - 3.5e-09 36.7 0.3 6.3e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ93659.1 - 1.4e-08 34.6 1.9 1.4e-08 34.6 1.3 2.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EAQ93659.1 - 1.2e-07 31.9 4.8 2.4e-07 30.9 0.5 2.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EAQ93659.1 - 3e-05 23.3 0.8 6.2e-05 22.3 0.5 1.5 1 0 0 1 1 1 1 NmrA-like family IQ PF00612.22 EAQ93659.1 - 4.5e-05 22.7 1.2 0.00015 21.0 0.9 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Epimerase PF01370.16 EAQ93659.1 - 0.00087 18.7 0.3 0.00087 18.7 0.2 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EAQ93659.1 - 0.024 14.2 0.6 0.062 12.8 0.4 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.20 EAQ93660.1 - 8.8e-11 42.0 2.6 4.2e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EAQ93660.1 - 0.00024 21.1 0.1 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EAQ93660.1 - 0.0072 16.0 0.1 0.77 9.3 0.1 2.1 2 0 0 2 2 2 2 KR domain Peptidase_M28 PF04389.12 EAQ93661.1 - 1.1e-37 129.5 0.0 1.5e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 PX PF00787.19 EAQ93662.1 - 8.1e-20 70.7 0.1 1.3e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 PX domain Alpha_GJ PF03229.8 EAQ93664.1 - 7.7 6.8 15.1 0.24 11.7 5.6 2.2 2 2 0 2 2 2 0 Alphavirus glycoprotein J Ribophorin_II PF05817.9 EAQ93665.1 - 1.7e-20 72.8 0.4 1.9e-16 59.4 0.1 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II Cep57_MT_bd PF06657.8 EAQ93666.1 - 5e-25 87.2 0.1 5e-25 87.2 0.1 7.2 6 1 1 7 7 7 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EAQ93666.1 - 2e-22 78.9 18.6 1.8e-17 63.0 6.6 8.2 4 3 3 7 7 7 4 Centrosome localisation domain of PPC89 MerR_2 PF13591.1 EAQ93666.1 - 0.0019 17.7 2.3 0.0019 17.7 1.6 5.0 7 0 0 7 7 7 1 MerR HTH family regulatory protein CCDC155 PF14662.1 EAQ93666.1 - 0.0033 17.0 20.2 0.0033 17.0 14.0 6.1 3 1 4 8 8 8 3 Coiled-coil region of CCDC155 DUF972 PF06156.8 EAQ93666.1 - 0.032 14.5 56.2 0.94 9.8 2.6 8.4 2 1 4 8 8 8 0 Protein of unknown function (DUF972) Fungal_trans PF04082.13 EAQ93667.1 - 1.5e-14 53.4 0.4 2.6e-14 52.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF605 PF04652.11 EAQ93667.1 - 3.2 7.0 9.9 5.6 6.2 6.9 1.4 1 0 0 1 1 1 0 Vta1 like Beta_elim_lyase PF01212.16 EAQ93668.1 - 9.4e-43 146.4 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EAQ93668.1 - 0.044 12.7 0.0 0.05 12.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Trehalase PF01204.13 EAQ93669.1 - 2.4e-87 293.7 7.1 9.7e-46 156.4 8.6 3.3 1 1 1 2 2 2 2 Trehalase Bromodomain PF00439.20 EAQ93670.1 - 5.8e-26 90.2 0.4 1.1e-25 89.3 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EAQ93670.1 - 3.5e-09 36.6 0.1 7.8e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ93670.1 - 4.3e-09 36.2 0.0 9.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAQ93670.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Aldedh PF00171.17 EAQ93673.1 - 2.6e-168 560.1 0.1 3e-168 559.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Gly_rich_SFCGS PF14272.1 EAQ93673.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycine-rich SFCGS HATPase_c PF02518.21 EAQ93676.1 - 3.7e-22 78.1 0.0 7.6e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAQ93676.1 - 8e-18 64.4 0.1 2.4e-16 59.7 0.0 2.5 1 1 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EAQ93676.1 - 7.1e-10 39.2 0.0 1.1e-08 35.4 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EAQ93676.1 - 1.2e-08 34.9 0.0 0.00062 19.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 EAQ93676.1 - 7.5e-07 29.0 1.1 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EAQ93676.1 - 0.00026 21.0 0.0 0.002 18.2 0.0 2.4 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.1 EAQ93676.1 - 0.00043 20.7 0.2 0.42 11.0 0.0 3.1 3 0 0 3 3 3 2 GAF domain PAS PF00989.19 EAQ93676.1 - 0.0019 17.9 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EAQ93676.1 - 0.0074 16.1 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PH_6 PF15406.1 EAQ93677.1 - 6.8e-46 154.9 3.1 6.8e-46 154.9 2.2 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EAQ93677.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 PH domain DUF4598 PF15370.1 EAQ93677.1 - 2.7 8.2 6.9 17 5.7 1.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) PH_4 PF15404.1 EAQ93677.1 - 3.3 7.2 0.0 3.3 7.2 0.0 3.3 4 0 0 4 4 4 0 Pleckstrin homology domain tRNA-synt_2 PF00152.15 EAQ93679.1 - 4.9e-70 235.9 0.0 6.6e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAQ93679.1 - 8.7e-11 41.5 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAQ93679.1 - 0.00012 21.3 0.1 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.10 EAQ93680.1 - 1.9e-19 68.6 3.2 2.2e-19 68.5 2.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EAQ93680.1 - 0.0017 17.7 1.6 0.0025 17.2 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) PG_binding_1 PF01471.13 EAQ93681.1 - 0.0027 17.6 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 2 Putative peptidoglycan binding domain Tropomyosin_1 PF12718.2 EAQ93681.1 - 0.16 11.8 2.4 0.27 11.0 0.1 2.3 1 1 1 2 2 2 0 Tropomyosin like Myosin_tail_1 PF01576.14 EAQ93681.1 - 0.19 9.3 6.1 0.33 8.6 4.2 1.2 1 0 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 EAQ93681.1 - 0.32 11.2 1.1 24 5.2 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CLTH PF10607.4 EAQ93682.1 - 2.7e-28 98.4 0.0 3.7e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EAQ93682.1 - 0.00048 19.7 0.4 0.00083 19.0 0.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger CRPA PF05745.6 EAQ93683.1 - 0.032 14.0 0.8 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF4064 PF13273.1 EAQ93683.1 - 0.7 10.0 12.2 0.08 13.0 2.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Prominin PF05478.6 EAQ93683.1 - 2.8 5.3 4.1 4.2 4.7 2.8 1.2 1 0 0 1 1 1 0 Prominin PPP4R2 PF09184.6 EAQ93684.1 - 3e-08 33.5 0.0 3e-08 33.5 0.0 4.0 4 0 0 4 4 4 1 PPP4R2 AAA_23 PF13476.1 EAQ93685.1 - 4.8e-26 92.3 0.1 4.8e-26 92.3 0.0 7.4 1 1 2 3 3 3 1 AAA domain SbcCD_C PF13558.1 EAQ93685.1 - 6.4e-11 42.0 0.1 3.6e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EAQ93685.1 - 6.1e-10 39.5 8.7 6.1e-06 26.4 0.5 4.0 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EAQ93685.1 - 3.3e-08 33.0 35.1 1.3e-07 31.0 0.0 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EAQ93685.1 - 0.00028 19.4 123.8 0.0006 18.4 0.0 7.2 2 1 5 8 8 8 4 AAA domain AAA_29 PF13555.1 EAQ93685.1 - 0.00085 18.8 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EAQ93685.1 - 0.0019 17.3 46.2 0.0026 16.8 13.7 4.9 4 2 0 4 4 4 2 AAA ATPase domain ABC_tran PF00005.22 EAQ93685.1 - 0.054 13.7 0.0 0.054 13.7 0.0 7.1 3 2 0 4 4 4 0 ABC transporter GATA PF00320.22 EAQ93687.1 - 6.5e-16 57.3 5.6 1.4e-15 56.2 3.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EAQ93687.1 - 8.1e-12 45.0 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EAQ93687.1 - 5e-09 36.4 0.0 2.3e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 EAQ93687.1 - 1.4e-06 28.1 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EAQ93687.1 - 2.9e-06 27.0 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EAQ93687.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EAQ93687.1 - 0.037 13.9 0.0 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain TF_Zn_Ribbon PF08271.7 EAQ93687.1 - 0.3 10.4 2.5 0.73 9.1 0.1 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding adh_short PF00106.20 EAQ93688.1 - 6.3e-22 78.2 0.3 1.2e-21 77.3 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAQ93688.1 - 4.7e-08 32.9 0.2 1.9e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAQ93688.1 - 0.00048 19.9 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAQ93688.1 - 0.0013 18.7 0.0 0.0089 16.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EAQ93688.1 - 0.021 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NACHT PF05729.7 EAQ93689.1 - 8.6e-10 38.5 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAQ93689.1 - 8.1e-07 29.2 0.1 3.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EAQ93689.1 - 0.018 14.0 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EAQ93689.1 - 0.052 12.3 0.0 0.094 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 EAQ93689.1 - 0.078 11.9 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain DUF948 PF06103.6 EAQ93689.1 - 0.11 12.4 0.2 0.42 10.5 0.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APS_kinase PF01583.15 EAQ93689.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase FAD-oxidase_C PF02913.14 EAQ93690.1 - 8.2e-62 208.7 0.3 1.3e-61 208.1 0.2 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAQ93690.1 - 1.7e-38 131.2 0.1 7.9e-38 129.0 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain Clr5 PF14420.1 EAQ93691.1 - 5.2e-08 32.6 1.4 2.2e-07 30.6 1.0 2.1 1 1 0 1 1 1 1 Clr5 domain PAT1 PF09770.4 EAQ93691.1 - 0.003 15.8 44.4 0.0041 15.4 30.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 HTH_21 PF13276.1 EAQ93691.1 - 0.0077 16.2 0.2 0.029 14.3 0.1 2.0 2 0 0 2 2 1 1 HTH-like domain CagX PF03524.10 EAQ93691.1 - 0.24 10.6 8.0 0.43 9.8 5.6 1.4 1 0 0 1 1 1 0 Conjugal transfer protein zf-DHHC PF01529.15 EAQ93691.1 - 0.3 10.4 1.0 0.4 10.0 0.7 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase FimP PF09766.4 EAQ93691.1 - 0.34 9.9 18.9 0.53 9.3 13.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 EAQ93691.1 - 0.49 9.0 3.3 0.65 8.6 2.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.1 EAQ93691.1 - 0.49 10.6 3.3 1.2 9.4 2.3 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2360 PF10152.4 EAQ93691.1 - 0.8 9.9 20.4 5.3 7.3 8.7 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF106 PF01956.11 EAQ93691.1 - 1.2 8.6 5.4 2.1 7.8 3.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 OATP PF03137.15 EAQ93691.1 - 1.7 6.5 2.3 2.4 6.1 1.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CDK5_activator PF03261.10 EAQ93691.1 - 1.9 7.7 8.9 2.7 7.2 6.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4557 PF15101.1 EAQ93691.1 - 2 8.2 15.5 3.7 7.3 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spt20 PF12090.3 EAQ93691.1 - 2.3 7.5 14.2 5.3 6.3 9.8 1.6 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.4 EAQ93691.1 - 2.8 6.0 14.7 4.4 5.4 10.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 REC114-like PF15165.1 EAQ93691.1 - 3.1 7.4 11.1 6 6.5 7.7 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like eIF-3_zeta PF05091.7 EAQ93691.1 - 4.5 5.7 12.0 6.3 5.2 8.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TPR_12 PF13424.1 EAQ93692.1 - 3.3e-21 74.9 0.1 9.1e-10 38.3 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EAQ93692.1 - 6.9e-15 54.4 1.1 0.00021 21.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAQ93692.1 - 0.0036 16.9 0.3 0.63 9.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAQ93692.1 - 0.027 14.1 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EAQ93692.1 - 0.048 13.5 1.1 2.4 8.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Amidase PF01425.16 EAQ93693.1 - 8.9e-67 225.8 0.1 1.2e-66 225.4 0.1 1.1 1 0 0 1 1 1 1 Amidase Meth_synt_2 PF01717.13 EAQ93693.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain BASP1 PF05466.7 EAQ93694.1 - 0.017 14.9 0.2 0.017 14.9 0.1 1.5 2 0 0 2 2 2 0 Brain acid soluble protein 1 (BASP1 protein) Troponin PF00992.15 EAQ93694.1 - 0.13 12.3 11.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Troponin Glyco_tranf_2_3 PF13641.1 EAQ93697.1 - 2.7e-13 50.2 0.2 3.6e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAQ93697.1 - 8.8e-07 28.3 0.0 2.1e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EAQ93697.1 - 0.038 13.6 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Spo7_2_N PF15407.1 EAQ93700.1 - 0.086 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 GWT1 PF06423.7 EAQ93701.1 - 1e-44 151.9 0.3 2.1e-44 150.9 0.2 1.6 1 0 0 1 1 1 1 GWT1 Pkinase PF00069.20 EAQ93702.1 - 1.3e-63 214.6 0.0 3.3e-63 213.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93702.1 - 7.4e-36 123.5 0.0 1.4e-30 106.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAQ93702.1 - 1.2e-05 24.3 0.0 0.013 14.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EAQ93702.1 - 9e-05 22.3 0.1 0.00038 20.2 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EAQ93702.1 - 0.016 14.2 0.1 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAQ93702.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.17 EAQ93703.1 - 5.3e-15 54.7 0.1 1.6e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAQ93703.1 - 1.2e-10 41.1 0.0 5.1e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAQ93703.1 - 4.3e-07 29.6 0.0 7.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAQ93703.1 - 0.012 15.4 0.1 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Glyco_hydro_76 PF03663.9 EAQ93704.1 - 9e-23 81.2 0.7 8.1e-14 51.7 0.0 4.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 ADK PF00406.17 EAQ93705.1 - 1.3e-19 70.5 0.0 9.2e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EAQ93705.1 - 4.8e-13 48.5 0.0 8.2e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid LETM1 PF07766.8 EAQ93706.1 - 2.9e-110 367.5 0.5 4.4e-110 366.9 0.3 1.2 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EAQ93706.1 - 1.5e-05 24.3 0.1 0.058 12.9 0.0 3.7 3 1 0 3 3 3 2 SAP domain PX PF00787.19 EAQ93707.1 - 9.2e-20 70.5 0.1 2.6e-19 69.0 0.1 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EAQ93707.1 - 1.3e-10 40.9 7.8 1.3e-07 31.0 1.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EAQ93707.1 - 4.3e-09 36.2 0.6 8.5e-09 35.2 0.4 1.4 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 EAQ93707.1 - 7.9e-05 22.3 3.9 0.00011 21.9 0.0 2.1 2 0 0 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 EAQ93707.1 - 0.00014 21.1 0.4 0.00021 20.5 0.3 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EAQ93707.1 - 0.012 15.4 0.5 0.031 14.1 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 EAQ93707.1 - 0.18 11.5 3.8 0.065 12.9 0.5 1.8 2 1 0 2 2 2 0 Laminin Domain II ADIP PF11559.3 EAQ93707.1 - 3 7.7 8.4 5.7 6.8 0.2 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding eIF3_subunit PF08597.5 EAQ93707.1 - 4.6 6.7 10.1 0.4 10.2 2.7 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit APG6 PF04111.7 EAQ93707.1 - 7.1 5.5 6.7 0.45 9.5 0.3 1.9 2 1 0 2 2 2 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 EAQ93707.1 - 8.8 6.1 14.1 0.18 11.6 0.8 3.1 3 1 0 3 3 3 0 Prefoldin subunit Peptidase_S8 PF00082.17 EAQ93708.1 - 4.6e-54 183.4 2.1 4.6e-54 183.4 1.5 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EAQ93708.1 - 1.3e-25 89.0 1.1 2.4e-25 88.1 0.8 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PhoD PF09423.5 EAQ93709.1 - 4.7e-06 25.4 0.1 0.00063 18.4 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Na_Ca_ex PF01699.19 EAQ93710.1 - 5.4e-34 116.7 24.6 3.1e-22 78.6 10.3 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SOBP PF15279.1 EAQ93710.1 - 3.3 8.0 15.3 8.3 6.6 10.6 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein KIAA1328 PF15369.1 EAQ93710.1 - 9.4 5.9 10.0 15 5.2 7.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 SPRY PF00622.23 EAQ93711.1 - 1.6e-05 24.9 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 SPRY domain DEAD PF00270.24 EAQ93712.1 - 4.7e-28 97.7 0.0 4.9e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAQ93712.1 - 1.5e-23 82.4 0.3 4.4e-23 80.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAQ93712.1 - 6.4e-06 26.1 0.1 0.00015 21.6 0.0 2.4 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAQ93712.1 - 0.032 13.0 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain PYC_OADA PF02436.13 EAQ93712.1 - 0.11 11.9 1.3 0.22 10.9 0.9 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain tRNA-synt_1 PF00133.17 EAQ93713.1 - 4e-150 500.7 0.0 5.4e-150 500.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EAQ93713.1 - 1.2e-20 73.5 0.0 2.7e-11 42.7 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EAQ93713.1 - 1.2e-17 64.0 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EAQ93713.1 - 0.015 14.4 0.0 0.36 9.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Tom37 PF10568.4 EAQ93714.1 - 4.4e-19 68.4 0.1 1.1e-18 67.2 0.1 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 EAQ93714.1 - 3.7e-17 62.7 0.0 3.6e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Tom37 C-terminal domain K_channel_TID PF07941.6 EAQ93714.1 - 7.2 6.9 8.8 0.92 9.7 2.7 2.1 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain PIG-U PF06728.8 EAQ93717.1 - 7.6e-84 281.7 26.8 9.1e-84 281.5 18.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EAQ93718.1 - 2.9e-112 374.5 0.1 2.9e-112 374.5 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EAQ93718.1 - 3.3e-07 30.3 0.0 2e-06 27.8 0.0 2.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Myc_N PF01056.13 EAQ93718.1 - 0.57 9.2 12.2 1.1 8.3 8.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region RRN9 PF10680.4 EAQ93719.1 - 7.3e-26 89.7 0.0 1.3e-24 85.6 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Kinesin PF00225.18 EAQ93720.1 - 2.5e-111 371.6 1.0 2.5e-111 371.6 0.7 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EAQ93720.1 - 1.7e-05 24.9 0.1 1.7e-05 24.9 0.1 5.1 3 1 2 5 5 5 1 Kinesin-associated microtubule-binding UPF0183 PF03676.9 EAQ93721.1 - 1e-36 126.3 0.0 5.5e-23 81.1 0.0 4.9 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Syja_N PF02383.13 EAQ93723.1 - 1.9e-90 302.8 0.0 2.4e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 EAQ93724.1 - 1e-46 158.2 4.4 2.6e-41 140.7 1.1 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EAQ93724.1 - 2.3e-13 50.6 1.6 9.1e-11 42.3 0.7 2.5 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAQ93724.1 - 2.2e-12 46.5 0.3 2.9e-11 42.9 0.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAQ93724.1 - 2.6e-08 33.5 0.1 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAQ93724.1 - 2.6e-06 26.7 0.5 3.2e-05 23.1 0.3 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ93724.1 - 0.0034 17.3 0.4 0.014 15.3 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAQ93724.1 - 0.024 13.8 0.5 0.12 11.5 0.0 2.2 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAQ93724.1 - 0.028 14.3 0.1 0.045 13.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EAQ93724.1 - 0.03 14.4 0.1 0.63 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAQ93724.1 - 0.049 13.0 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain CTP_transf_3 PF02348.14 EAQ93724.1 - 0.12 11.9 0.4 0.36 10.4 0.3 1.6 1 1 1 2 2 2 0 Cytidylyltransferase Mitofilin PF09731.4 EAQ93725.1 - 5.8e-163 543.6 9.7 7.1e-163 543.3 6.7 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein 4HB_MCP_1 PF12729.2 EAQ93725.1 - 0.0078 15.5 8.8 0.015 14.6 6.1 1.4 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction DUF1759 PF03564.10 EAQ93725.1 - 0.27 11.0 4.9 0.59 9.9 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) LUC7 PF03194.10 EAQ93725.1 - 1.8 8.0 13.4 0.73 9.3 6.1 2.2 1 1 1 2 2 2 0 LUC7 N_terminus Mur_ligase_M PF08245.7 EAQ93726.1 - 0.0012 18.9 0.2 0.0048 16.9 0.1 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EAQ93726.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Ribosomal_L6e PF01159.14 EAQ93726.1 - 0.086 13.0 0.4 0.16 12.1 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e Mur_ligase_C PF02875.16 EAQ93727.1 - 0.014 15.3 0.0 0.046 13.7 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF1479 PF07350.7 EAQ93727.1 - 0.15 10.5 0.3 0.25 9.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) ADH_N PF08240.7 EAQ93728.1 - 8.5e-29 99.5 0.9 1.7e-28 98.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAQ93728.1 - 2.1e-23 82.3 1.4 4e-23 81.3 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAQ93728.1 - 8.7e-07 29.8 0.3 2.9e-06 28.2 0.1 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EAQ93728.1 - 0.0067 16.9 0.1 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EAQ93728.1 - 0.0074 15.6 0.5 0.031 13.6 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EAQ93728.1 - 0.14 12.0 2.1 2.8 7.7 1.5 2.2 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hydro_2 PF00703.16 EAQ93729.1 - 4.3e-12 46.4 0.1 1e-11 45.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EAQ93729.1 - 4.2e-10 39.4 0.2 1.6e-09 37.5 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EAQ93729.1 - 0.0001 21.3 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ras PF00071.17 EAQ93730.1 - 7.5e-42 142.4 0.0 1.1e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAQ93730.1 - 1.3e-15 57.9 0.0 1.9e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAQ93730.1 - 9.5e-12 44.5 0.0 4.2e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAQ93730.1 - 0.00037 19.7 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAQ93730.1 - 0.00056 19.8 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EAQ93730.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EAQ93730.1 - 0.0031 16.7 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EAQ93730.1 - 0.0033 17.5 0.0 0.0065 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAQ93730.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EAQ93730.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAQ93730.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAQ93730.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EAQ93730.1 - 0.087 12.3 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EAQ93730.1 - 0.091 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EAQ93730.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EAQ93730.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase adh_short PF00106.20 EAQ93731.1 - 1.4e-13 51.0 0.4 1.2e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAQ93731.1 - 0.00019 21.1 5.4 0.031 13.9 0.9 2.5 2 1 0 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.14 EAQ93733.1 - 1.6e-44 151.1 0.0 5.5e-44 149.4 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAQ93733.1 - 7.1e-05 22.2 0.0 9.4e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF1749 PF08538.5 EAQ93734.1 - 2.9e-54 184.0 0.0 3.6e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EAQ93734.1 - 1.5e-07 31.5 0.1 1.9e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAQ93734.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Mpt_N PF09176.6 EAQ93734.1 - 0.089 12.6 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal HARP PF07443.8 EAQ93735.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) RNase_T PF00929.19 EAQ93736.1 - 1.6e-06 28.5 0.0 1.9e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 Exonuclease DUF1399 PF07173.7 EAQ93738.1 - 9.7e-22 77.7 0.1 1.7e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Lipase_3 PF01764.20 EAQ93739.1 - 3.6e-10 39.6 0.0 6.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 EAQ93740.1 - 2.1e-48 164.3 1.5 4.8e-48 163.1 1.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 EAQ93740.1 - 1.3e-33 116.0 0.6 9.8e-33 113.1 0.4 2.1 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 EAQ93740.1 - 9.1e-08 31.9 0.2 1.9e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family VHL PF01847.11 EAQ93740.1 - 5.3e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein Peptidase_S15 PF02129.13 EAQ93740.1 - 6.5e-05 22.4 2.0 0.0016 17.9 1.2 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EAQ93740.1 - 0.0013 18.0 0.4 0.0029 16.9 0.3 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 EAQ93740.1 - 0.0013 18.2 0.6 0.0029 17.0 0.4 1.5 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EAQ93740.1 - 0.0059 15.8 1.5 0.0098 15.1 1.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Tannase PF07519.6 EAQ93740.1 - 0.16 10.6 2.0 0.63 8.6 0.0 2.0 1 1 1 2 2 2 0 Tannase and feruloyl esterase Abhydrolase_3 PF07859.8 EAQ93740.1 - 0.26 10.8 3.6 8 5.9 2.5 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Zn_Tnp_IS1595 PF12760.2 EAQ93741.1 - 2.9 7.7 5.5 0.73 9.6 1.0 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Glyco_hydro_11 PF00457.12 EAQ93743.1 - 2.9e-61 206.0 10.0 3.3e-61 205.8 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 IL28A PF15177.1 EAQ93744.1 - 0.063 12.7 0.5 0.084 12.3 0.3 1.2 1 0 0 1 1 1 0 Interleukin-28A Dicty_REP PF05086.7 EAQ93744.1 - 2.6 5.6 7.1 2.9 5.5 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NCA2 PF08637.5 EAQ93745.1 - 0.041 12.7 0.3 0.054 12.3 0.2 1.1 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 DPRP PF04244.8 EAQ93745.1 - 0.18 11.3 1.9 0.28 10.6 1.3 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Allexi_40kDa PF05549.6 EAQ93745.1 - 0.27 10.5 1.5 0.38 10.0 1.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein FlgN PF05130.7 EAQ93745.1 - 0.41 10.8 9.8 0.74 10.0 6.8 1.4 1 0 0 1 1 1 0 FlgN protein ECH PF00378.15 EAQ93746.1 - 1.4e-11 44.0 0.6 1.5e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 EAQ93747.1 - 2.3e-53 181.0 8.7 7e-30 103.7 0.6 3.2 2 1 1 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.1 EAQ93747.1 - 2.3e-05 25.2 0.0 6.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ferritin_2 PF13668.1 EAQ93749.1 - 1.1e-15 57.8 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF1996 PF09362.5 EAQ93751.1 - 5.7e-88 294.5 1.8 6.9e-88 294.2 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_2 PF12796.2 EAQ93754.1 - 8.3e-109 356.1 20.0 2.3e-13 50.3 0.0 11.2 2 1 7 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 EAQ93754.1 - 1.1e-90 293.1 48.0 7.4e-07 28.6 0.0 19.8 19 0 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 EAQ93754.1 - 2.6e-53 177.5 16.9 4.4e-06 27.0 0.0 15.5 6 5 10 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ93754.1 - 2.1e-52 169.8 19.1 0.0045 17.0 0.0 18.3 19 0 0 19 19 19 14 Ankyrin repeat Ank_5 PF13857.1 EAQ93754.1 - 5.5e-52 172.6 42.2 7.9e-07 29.1 0.1 16.7 8 4 10 19 19 19 14 Ankyrin repeats (many copies) Ank PF00023.25 EAQ93755.1 - 2.4e-08 33.3 1.2 2.3e-05 23.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EAQ93755.1 - 3.5e-08 33.6 1.1 0.0019 18.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Peptidase_S8 PF00082.17 EAQ93755.1 - 1.7e-06 27.4 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Ank_3 PF13606.1 EAQ93755.1 - 1.8e-06 27.6 3.4 0.0064 16.6 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 EAQ93755.1 - 4.3e-06 27.0 0.9 0.11 13.0 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAQ93755.1 - 2.3e-05 24.4 0.8 0.29 11.4 0.0 4.8 2 2 2 4 4 4 1 Ankyrin repeats (many copies) DUF2520 PF10728.4 EAQ93755.1 - 0.0011 18.4 0.3 0.0024 17.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) HET PF06985.6 EAQ93756.1 - 1.6e-12 47.7 0.0 3.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 EAQ93762.1 - 7.9e-29 100.4 0.0 9.7e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAD PF03068.10 EAQ93763.1 - 3.1e-30 104.8 0.0 1.8e-29 102.4 0.0 2.1 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) DLH PF01738.13 EAQ93765.1 - 1.7e-10 40.5 0.2 0.0042 16.4 0.0 3.3 3 1 0 3 3 3 3 Dienelactone hydrolase family NAD_binding_1 PF00175.16 EAQ93767.1 - 3.4e-27 95.1 0.0 5.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EAQ93767.1 - 4.4e-23 80.8 0.1 1e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EAQ93767.1 - 4.1e-22 78.1 0.0 8e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EAQ93767.1 - 0.00039 20.3 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain p450 PF00067.17 EAQ93768.1 - 6.6e-69 232.6 0.0 7.8e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vip3A_N PF12495.3 EAQ93769.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF1680 PF07944.7 EAQ93770.1 - 8.7e-136 453.2 0.1 1e-135 453.0 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Mito_fiss_reg PF05308.6 EAQ93772.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2457 PF10446.4 EAQ93772.1 - 0.44 9.2 4.3 0.62 8.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CAP_N PF01213.14 EAQ93772.1 - 1.2 8.3 3.8 2 7.6 2.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal APC_CDC26 PF10471.4 EAQ93772.1 - 7.7 7.3 8.9 13 6.6 5.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 EAQ93774.1 - 6.4e-09 35.3 0.0 5.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAQ93774.1 - 0.088 11.8 0.0 0.52 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Toxin_61 PF15538.1 EAQ93774.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 61 Aldo_ket_red PF00248.16 EAQ93776.1 - 2.8e-65 219.9 0.0 3.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.19 EAQ93776.1 - 0.054 12.7 0.1 0.68 9.1 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Sporozoite_P67 PF05642.6 EAQ93781.1 - 0.56 8.0 4.5 0.72 7.6 3.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PHD_2 PF13831.1 EAQ93781.1 - 1.1 8.5 6.0 9.3 5.6 0.4 2.2 2 0 0 2 2 2 0 PHD-finger Sigma70_ner PF04546.8 EAQ93781.1 - 1.7 8.2 3.8 2.3 7.7 2.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region HD_5 PF13487.1 EAQ93782.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 HD domain Zip PF02535.17 EAQ93783.1 - 5.7e-23 81.4 24.5 5.7e-12 45.2 2.4 3.4 1 1 2 3 3 3 3 ZIP Zinc transporter MscS_TM PF12794.2 EAQ93783.1 - 8.3 4.9 9.4 0.36 9.3 0.9 2.3 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DnaJ PF00226.26 EAQ93784.1 - 5.7e-12 45.1 0.2 1.4e-11 43.9 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EAQ93785.1 - 2.9e-18 65.6 0.1 5.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ93785.1 - 8.5e-09 35.1 10.6 1.5e-08 34.4 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 EAQ93786.1 - 1.9e-18 66.4 0.1 2.3e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain cNMP_binding PF00027.24 EAQ93788.1 - 4.5e-36 122.5 0.0 5.4e-18 64.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EAQ93788.1 - 1.9e-11 42.8 0.1 1 9.6 0.0 7.5 7 0 0 7 7 7 2 Leucine Rich repeat F-box PF00646.28 EAQ93788.1 - 1.3e-06 27.9 3.3 1.4e-06 27.8 0.1 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EAQ93788.1 - 4.1e-05 23.2 0.3 0.00018 21.1 0.2 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAQ93788.1 - 0.00029 20.5 0.1 0.85 9.4 0.0 3.6 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EAQ93788.1 - 0.0012 18.5 5.0 17 5.9 0.1 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat DUF1459 PF07312.6 EAQ93788.1 - 0.045 13.6 0.2 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) LRR_4 PF12799.2 EAQ93788.1 - 0.18 11.4 0.0 20 4.9 0.0 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAQ93788.1 - 0.9 10.0 6.3 29 5.4 0.1 4.9 5 0 0 5 5 5 0 Leucine rich repeat Bax1-I PF01027.15 EAQ93789.1 - 2.9e-32 111.9 10.5 4.1e-32 111.4 7.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.16 EAQ93790.1 - 1.7e-58 196.9 0.0 1.9e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HET PF06985.6 EAQ93791.1 - 1.5e-32 112.6 0.2 1.2e-23 83.8 0.0 3.2 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EAQ93792.1 - 5e-09 36.4 1.8 0.00022 21.3 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAQ93792.1 - 0.0018 18.3 1.6 0.16 12.0 0.1 2.9 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EAQ93792.1 - 0.1 12.5 0.4 0.33 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EAQ93792.1 - 0.14 11.9 0.1 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Slx4 PF09494.5 EAQ93793.1 - 2.1e-19 69.0 0.0 4.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.14 EAQ93793.1 - 1.9e-05 23.7 18.2 0.15 11.7 0.9 4.7 3 0 0 3 3 3 3 AT hook motif NUDIX PF00293.23 EAQ93793.1 - 0.01 15.4 0.1 0.079 12.6 0.1 2.2 1 1 0 1 1 1 0 NUDIX domain Ribosomal_S21e PF01249.13 EAQ93794.1 - 2.1e-38 130.1 0.1 2.3e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SKG6 PF08693.5 EAQ93796.1 - 3.2 7.1 7.1 7.3 6.0 4.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain adh_short PF00106.20 EAQ93797.1 - 1.2e-26 93.6 0.1 1.7e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAQ93797.1 - 5e-25 88.6 0.0 6.2e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAQ93797.1 - 2.6e-06 27.2 0.1 3.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ93797.1 - 0.0034 16.8 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAQ93797.1 - 0.0086 15.8 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2974 PF11187.3 EAQ93797.1 - 0.028 13.7 0.0 0.085 12.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) PAF-AH_p_II PF03403.8 EAQ93798.1 - 8.2e-05 21.0 0.0 9.3e-05 20.8 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EAQ93798.1 - 0.00044 20.0 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EAQ93798.1 - 0.022 13.6 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EAQ93798.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Zn_clus PF00172.13 EAQ93799.1 - 5.9e-05 22.8 4.2 0.00017 21.4 2.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fructosamin_kin PF03881.9 EAQ93800.1 - 1.8e-11 43.5 0.0 5.8e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase CorA PF01544.13 EAQ93801.1 - 1.5e-16 60.2 0.1 3e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S8 PF00082.17 EAQ93801.1 - 1.9e-16 60.0 0.5 3.3e-16 59.2 0.3 1.3 1 0 0 1 1 1 1 Subtilase family ACR_tran PF00873.14 EAQ93801.1 - 0.064 10.6 1.6 0.099 10.0 1.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TMF_TATA_bd PF12325.3 EAQ93801.1 - 0.57 9.9 1.6 1.1 8.9 1.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Acetyltransf_9 PF13527.1 EAQ93802.1 - 3.2e-05 23.7 0.0 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAQ93802.1 - 0.00016 21.6 0.1 0.028 14.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAQ93802.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 EAQ93805.1 - 0.034 14.0 4.5 0.059 13.2 3.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimer_Tnp_hAT PF05699.9 EAQ93808.1 - 6.4e-16 57.7 0.2 1.6e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4066 PF13278.1 EAQ93809.1 - 3.8e-16 58.8 0.0 5.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAQ93809.1 - 1.2e-06 28.0 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family WD40 PF00400.27 EAQ93810.1 - 3.9e-13 48.7 10.9 3.2e-08 33.1 0.2 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 EAQ93810.1 - 0.042 13.7 3.1 0.11 12.3 2.2 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family PHD PF00628.24 EAQ93810.1 - 0.68 9.6 5.5 12 5.6 0.3 3.0 2 0 0 2 2 2 0 PHD-finger Cactin_mid PF10312.4 EAQ93811.1 - 1e-65 220.5 3.5 1.4e-65 220.1 2.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EAQ93811.1 - 2.6e-54 182.0 4.5 4.1e-54 181.4 3.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein dNK PF01712.14 EAQ93811.1 - 0.043 13.7 0.3 0.096 12.5 0.2 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF1087 PF06465.8 EAQ93811.1 - 0.048 13.5 4.9 0.45 10.4 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Vitellogenin_N PF01347.17 EAQ93811.1 - 0.13 10.4 0.1 0.18 10.0 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region Fork_head PF00250.13 EAQ93813.1 - 9.1e-17 60.8 0.1 1.8e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Fork head domain XLF PF09302.6 EAQ93814.1 - 7.6e-41 139.7 0.0 1.2e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) PBP1_TM PF14812.1 EAQ93814.1 - 7.4 6.9 9.0 59 4.0 3.5 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phage_HK97_TLTM PF06120.6 EAQ93815.1 - 0.00018 20.9 0.2 0.00032 20.1 0.1 1.3 1 0 0 1 1 1 1 Tail length tape measure protein Yip1 PF04893.12 EAQ93815.1 - 0.035 13.5 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Herpes_gE PF02480.11 EAQ93815.1 - 0.13 10.4 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ank_2 PF12796.2 EAQ93817.1 - 4.4e-08 33.3 0.0 0.0019 18.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAQ93817.1 - 5.1e-08 32.9 0.0 0.31 11.3 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAQ93817.1 - 5.2e-08 32.3 0.2 0.86 10.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EAQ93817.1 - 2e-06 28.1 0.2 0.14 12.6 0.0 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EAQ93817.1 - 9.6e-05 22.0 0.4 0.6 10.0 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat RVT_1 PF00078.22 EAQ93820.1 - 1.1e-31 109.8 0.0 2.5e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SlyX PF04102.7 EAQ93820.1 - 0.005 17.1 4.1 0.068 13.5 0.7 2.9 1 1 1 2 2 2 2 SlyX CorA PF01544.13 EAQ93820.1 - 0.052 12.5 1.9 0.11 11.5 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Mnd1 PF03962.10 EAQ93820.1 - 0.21 11.2 1.5 0.54 9.8 1.0 1.6 1 0 0 1 1 1 0 Mnd1 family DUF4226 PF10774.4 EAQ93820.1 - 0.29 11.2 5.9 0.097 12.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Atg14 PF10186.4 EAQ93822.1 - 1.3e-21 76.8 0.0 2.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EAQ93822.1 - 0.00051 19.2 3.5 0.11 11.4 0.0 2.5 3 0 0 3 3 3 1 Autophagy protein Apg6 ABC_tran_2 PF12848.2 EAQ93822.1 - 0.36 10.7 6.9 0.67 9.8 4.8 1.4 1 0 0 1 1 1 0 ABC transporter SKG6 PF08693.5 EAQ93823.1 - 0.00026 20.2 1.1 0.00073 18.7 0.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EAQ93823.1 - 0.0075 14.5 0.0 0.012 13.8 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 EAQ93823.1 - 0.0083 15.6 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3481 PF11980.3 EAQ93823.1 - 0.042 13.6 0.1 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) EphA2_TM PF14575.1 EAQ93823.1 - 0.081 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EAQ93823.1 - 0.086 12.4 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Granulin PF00396.13 EAQ93823.1 - 1.3 9.1 7.0 1 9.4 1.8 2.4 2 0 0 2 2 2 0 Granulin MULE PF10551.4 EAQ93826.1 - 5.6e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAQ93826.1 - 1.4e-06 28.7 0.4 3.4e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.13 EAQ93826.1 - 2.7e-05 22.9 0.0 4.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family AT_hook PF02178.14 EAQ93826.1 - 2.4 8.1 26.2 0.18 11.5 3.6 4.0 3 0 0 3 3 3 0 AT hook motif Sporozoite_P67 PF05642.6 EAQ93828.1 - 0.02 12.7 5.5 0.024 12.5 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Maff2 PF12750.2 EAQ93828.1 - 0.039 13.4 1.5 0.13 11.7 0.9 2.0 2 0 0 2 2 2 0 Maff2 family MFS_1 PF07690.11 EAQ93829.1 - 2e-41 141.9 55.8 2e-41 141.9 38.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Polyketide_cyc2 PF10604.4 EAQ93830.1 - 1.1e-10 41.8 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF3102 PF11300.3 EAQ93830.1 - 0.03 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Polyketide_cyc PF03364.15 EAQ93830.1 - 0.088 12.8 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Glyco_hydro_11 PF00457.12 EAQ93832.1 - 3.8e-60 202.3 20.9 9.1e-58 194.6 14.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 11 ADH_zinc_N PF00107.21 EAQ93833.1 - 3.6e-23 81.5 0.6 6.6e-23 80.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAQ93833.1 - 1.2e-21 76.5 0.9 3e-21 75.2 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 EAQ93833.1 - 0.0056 15.1 0.4 0.0097 14.3 0.3 1.3 1 0 0 1 1 1 1 AMP-binding enzyme GCD14 PF08704.5 EAQ93833.1 - 0.068 12.6 0.3 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF3521 PF12035.3 EAQ93833.1 - 0.18 11.6 0.2 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) ELFV_dehydrog PF00208.16 EAQ93833.1 - 0.63 9.5 4.1 7.8 5.9 0.9 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase p450 PF00067.17 EAQ93834.1 - 3.9e-65 220.1 0.0 4.8e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EAQ93835.1 - 5.5e-09 35.2 0.3 1.4e-07 30.6 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EAQ93835.1 - 1.2e-07 31.6 6.8 3.2e-05 24.0 1.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAQ93835.1 - 2.6e-07 30.4 13.5 0.00054 20.1 4.1 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAQ93835.1 - 2.2e-06 27.6 15.3 0.00035 20.7 4.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 EAQ93835.1 - 1.8e-05 24.5 10.1 4.3e-05 23.3 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 EAQ93835.1 - 3e-05 24.0 2.4 0.1 12.7 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAQ93835.1 - 0.0059 16.7 5.2 0.86 9.9 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAQ93835.1 - 0.069 13.0 6.8 1.4 8.9 1.7 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EAQ93835.1 - 4 7.6 7.9 8 6.6 0.1 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) F-box-like PF12937.2 EAQ93836.1 - 0.017 14.8 2.1 0.057 13.1 1.4 1.9 1 1 0 1 1 1 0 F-box-like Smr PF01713.16 EAQ93838.1 - 0.09 12.9 0.0 8.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Smr domain Glyco_hydro_11 PF00457.12 EAQ93839.1 - 1.5e-81 272.1 16.3 1.8e-81 271.8 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 RHIM PF12721.2 EAQ93839.1 - 3.5 8.0 7.7 9.9 6.6 0.1 3.6 3 1 0 3 3 3 0 RIP homotypic interaction motif DUF1399 PF07173.7 EAQ93846.1 - 2.9e-22 79.4 0.1 8.9e-16 58.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Glyco_hydro_75 PF07335.6 EAQ93849.1 - 6.7e-39 133.2 0.0 1e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Colipase-like PF15083.1 EAQ93849.1 - 0.5 10.3 3.3 10 6.1 0.2 2.2 2 0 0 2 2 2 0 Colipase-like APH PF01636.18 EAQ93850.1 - 4.6e-11 42.8 0.9 1.5e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAQ93850.1 - 4.6e-07 29.6 0.1 6.2e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EAQ93850.1 - 0.013 14.6 0.1 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Malic_M PF03949.10 EAQ93852.1 - 3.1e-79 266.1 0.1 4.2e-79 265.7 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EAQ93852.1 - 4.9e-39 133.7 0.0 3.3e-26 91.9 0.0 2.3 2 0 0 2 2 2 2 Malic enzyme, N-terminal domain Ribosomal_L14 PF00238.14 EAQ93853.1 - 5e-32 110.2 0.0 5.6e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e HET PF06985.6 EAQ93854.1 - 2.3e-21 76.4 4.5 2.7e-16 59.9 0.2 3.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2413 PF10310.4 EAQ93856.1 - 7.1e-152 506.2 0.0 8.1e-152 506.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EAQ93856.1 - 0.11 12.5 1.6 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DOMON PF03351.12 EAQ93857.1 - 0.00072 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 DOMON domain Abhydrolase_1 PF00561.15 EAQ93857.1 - 0.15 11.6 0.8 0.4 10.2 0.5 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Zip PF02535.17 EAQ93858.1 - 8.9e-51 172.7 0.4 1.1e-50 172.4 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM-7TMR_HD PF07698.6 EAQ93860.1 - 0.0094 15.4 1.7 0.0094 15.4 1.2 2.2 2 0 0 2 2 2 1 7TM receptor with intracellular HD hydrolase Peptidase_C14 PF00656.17 EAQ93861.1 - 5.6e-29 101.5 1.6 8.1e-15 55.1 0.3 2.2 1 1 0 2 2 2 2 Caspase domain WW PF00397.21 EAQ93862.1 - 1.9e-05 24.4 7.8 1.9e-05 24.4 5.4 2.5 2 0 0 2 2 2 1 WW domain BRO1 PF03097.13 EAQ93862.1 - 0.068 11.9 0.5 0.091 11.4 0.4 1.1 1 0 0 1 1 1 0 BRO1-like domain DUF4404 PF14357.1 EAQ93862.1 - 0.078 13.4 3.1 0.13 12.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) BAR PF03114.13 EAQ93862.1 - 1.1 8.6 5.5 1.6 8.1 3.8 1.1 1 0 0 1 1 1 0 BAR domain Gly-zipper_OmpA PF13436.1 EAQ93862.1 - 1.2 8.7 10.4 0.16 11.6 4.2 1.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain LSM PF01423.17 EAQ93863.1 - 2.9e-19 68.3 0.8 3.3e-19 68.1 0.5 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 EAQ93864.1 - 2.1e-60 204.0 19.3 6.5e-49 166.4 8.2 2.1 1 1 1 2 2 2 2 Nineteen complex-related protein 2 DUF948 PF06103.6 EAQ93864.1 - 0.09 12.6 0.6 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) LptE PF04390.7 EAQ93864.1 - 0.09 12.5 3.9 0.1 12.3 0.0 2.3 1 1 1 2 2 2 0 Lipopolysaccharide-assembly Toxin_43 PF15604.1 EAQ93864.1 - 0.59 10.1 7.1 1.4 8.9 4.7 1.8 1 1 1 2 2 2 0 Putative toxin 43 DUF3844 PF12955.2 EAQ93865.1 - 1.8e-36 124.3 2.4 2.9e-36 123.6 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) MFS_1 PF07690.11 EAQ93867.1 - 2.3e-33 115.3 28.4 6.3e-32 110.6 9.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Phage_holin_1 PF04531.8 EAQ93867.1 - 5.6 7.1 5.5 6.4 6.9 0.5 2.6 2 0 0 2 2 2 0 Bacteriophage holin Glyco_tranf_2_3 PF13641.1 EAQ93868.1 - 8.8e-21 74.7 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EAQ93868.1 - 6e-10 38.6 0.0 5.2e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EAQ93868.1 - 3.7e-07 30.0 2.2 3.7e-07 30.0 1.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EAQ93868.1 - 4.5e-06 26.4 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Beta-lactamase PF00144.19 EAQ93869.1 - 1.8e-28 99.5 3.4 7.7e-20 71.1 0.1 2.5 3 0 0 3 3 3 2 Beta-lactamase CHRD PF07452.7 EAQ93871.1 - 0.15 12.6 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 CHRD domain Sugar_tr PF00083.19 EAQ93872.1 - 1.1e-114 383.4 23.5 1.3e-114 383.2 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ93872.1 - 1.4e-23 83.2 42.2 4.9e-21 74.8 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAQ93872.1 - 0.001 17.4 3.8 0.001 17.4 2.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OPT PF03169.10 EAQ93873.1 - 3.2e-85 286.8 45.2 4e-85 286.5 31.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Asp PF00026.18 EAQ93875.1 - 5.2e-76 255.9 6.3 6.1e-76 255.6 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAQ93875.1 - 6.7e-09 35.9 0.1 3.4e-07 30.3 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAQ93875.1 - 0.00013 22.4 1.3 0.054 13.9 0.3 3.1 2 1 0 2 2 2 2 Aspartyl protease PIF1 PF05970.9 EAQ93876.1 - 5.9e-06 25.4 0.2 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EAQ93876.1 - 0.00012 22.1 0.0 0.00046 20.2 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain HA PF03457.9 EAQ93876.1 - 0.012 15.6 0.1 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 Helicase associated domain Tim17 PF02466.14 EAQ93878.1 - 3.7 7.6 8.7 12 5.9 6.0 1.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EAQ93878.1 - 5.2 7.3 6.7 1.4 9.1 0.7 2.4 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Pro_dh PF01619.13 EAQ93879.1 - 2.8e-39 134.9 0.0 4.9e-39 134.1 0.0 1.5 1 1 0 1 1 1 1 Proline dehydrogenase HTH_5 PF01022.15 EAQ93879.1 - 0.051 13.2 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Fungal_trans PF04082.13 EAQ93880.1 - 8.1e-14 51.1 0.0 1.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ93880.1 - 1.8e-08 34.1 7.2 4e-08 33.0 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EAQ93881.1 - 2e-23 82.6 22.7 3.3e-23 81.9 15.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EAQ93881.1 - 0.63 10.1 0.0 0.63 10.1 0.0 2.6 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Metallophos PF00149.23 EAQ93882.1 - 8.2e-11 41.6 0.7 8.2e-11 41.6 0.5 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase NIF PF03031.13 EAQ93884.1 - 2.9e-36 124.5 0.1 4.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NMO PF03060.10 EAQ93886.1 - 3.8e-36 124.9 11.3 6.1e-34 117.6 7.8 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAQ93886.1 - 9.2e-09 34.6 0.2 1.7e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAQ93886.1 - 1.7e-05 23.8 5.7 3.2e-05 22.9 4.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase OpuAC PF04069.7 EAQ93886.1 - 0.047 13.0 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system DHO_dh PF01180.16 EAQ93886.1 - 0.15 11.0 0.5 0.23 10.3 0.3 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SnoaL PF07366.7 EAQ93887.1 - 1.7e-13 50.2 0.0 1e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EAQ93887.1 - 3.1e-06 27.5 0.0 6.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain RhoGAP PF00620.22 EAQ93888.1 - 9.7e-16 57.7 0.0 2.4e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Methyltransf_31 PF13847.1 EAQ93889.1 - 6.4e-06 25.8 0.0 8.5e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAQ93889.1 - 3.2e-05 24.4 0.0 4.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAQ93889.1 - 0.0012 19.2 0.0 0.0025 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAQ93889.1 - 0.019 15.3 0.1 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EAQ93889.1 - 0.02 14.5 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EAQ93889.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PTS_2-RNA PF01885.11 EAQ93890.1 - 8.3e-14 51.3 0.0 4.1e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family AP_endonuc_2 PF01261.19 EAQ93891.1 - 2e-36 125.3 0.0 2.2e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 EAQ93893.1 - 3.4e-45 154.2 55.1 1e-43 149.4 38.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAQ93893.1 - 6.5e-18 64.5 26.1 2.2e-16 59.4 9.9 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EAQ93893.1 - 3e-14 52.1 16.8 3e-14 52.1 11.6 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EAQ93893.1 - 0.0032 15.5 5.1 0.29 9.1 0.6 2.4 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3318 PF11780.3 EAQ93893.1 - 0.075 12.6 0.7 0.15 11.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) MFS_1_like PF12832.2 EAQ93893.1 - 0.21 11.3 5.2 0.31 10.8 0.2 2.7 2 0 0 2 2 2 0 MFS_1 like family zf-CCHC PF00098.18 EAQ93894.1 - 0.00015 21.5 3.7 0.00025 20.8 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle PspA_IM30 PF04012.7 EAQ93894.1 - 0.0007 19.0 4.7 0.0011 18.3 3.2 1.3 1 0 0 1 1 1 1 PspA/IM30 family COG2 PF06148.6 EAQ93894.1 - 0.0025 17.7 3.0 0.0045 16.8 2.1 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF148 PF02520.12 EAQ93894.1 - 0.012 15.3 4.9 0.025 14.3 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 IncA PF04156.9 EAQ93894.1 - 0.017 14.7 3.5 0.025 14.1 2.4 1.2 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EAQ93894.1 - 0.018 13.7 5.1 0.025 13.2 3.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 EAQ93894.1 - 0.033 13.1 1.7 0.044 12.7 1.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 EAQ93894.1 - 0.037 13.8 8.2 0.12 12.2 4.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0240 PF06784.6 EAQ93894.1 - 0.068 12.8 0.9 0.14 11.8 0.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0240) TPR_MLP1_2 PF07926.7 EAQ93894.1 - 0.087 12.5 6.6 0.25 11.1 4.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 EAQ93894.1 - 0.1 12.9 5.5 0.27 11.6 3.7 1.8 1 1 0 1 1 1 0 SlyX VIT1 PF01988.14 EAQ93894.1 - 0.14 11.6 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 VIT family DUF1899 PF08953.6 EAQ93894.1 - 0.14 11.8 0.1 6.4 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) Baculo_PEP_C PF04513.7 EAQ93894.1 - 0.22 11.3 10.7 0.33 10.7 7.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EAQ93894.1 - 0.24 10.5 4.2 0.34 10.0 2.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EAQ93894.1 - 0.54 10.0 4.1 1.1 9.1 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MIS13 PF08202.6 EAQ93894.1 - 0.65 9.0 6.3 1.2 8.0 4.3 1.5 1 1 1 2 2 2 0 Mis12-Mtw1 protein family FlaC_arch PF05377.6 EAQ93894.1 - 0.66 9.9 6.7 0.22 11.4 1.3 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Paramyx_P_V_C PF03210.8 EAQ93894.1 - 1.6 8.5 7.1 0.92 9.3 2.0 2.2 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal DDE_1 PF03184.14 EAQ93895.1 - 1e-46 158.8 0.0 1.6e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EAQ93895.1 - 5.2e-12 45.1 0.0 1.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SpoIIID PF12116.3 EAQ93895.1 - 0.037 13.9 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D DUF904 PF06005.7 EAQ93895.1 - 0.15 12.3 0.7 0.71 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) adh_short_C2 PF13561.1 EAQ93896.1 - 2.6e-32 112.5 0.2 3.2e-32 112.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAQ93896.1 - 4.8e-29 101.4 2.2 5.6e-29 101.2 1.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAQ93896.1 - 6.9e-14 51.9 0.4 9.4e-14 51.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAQ93896.1 - 0.00035 20.0 0.2 0.00095 18.6 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EAQ93896.1 - 0.0012 17.9 0.2 0.0028 16.7 0.1 1.7 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EAQ93896.1 - 0.0021 17.7 2.3 0.005 16.5 1.6 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AdoHcyase_NAD PF00670.16 EAQ93896.1 - 0.0051 16.6 0.5 0.0085 15.9 0.3 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sugar_tr PF00083.19 EAQ93897.1 - 1.1e-78 264.8 22.4 1.3e-78 264.6 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAQ93897.1 - 1.5e-22 79.8 64.5 2.4e-20 72.5 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 EAQ93897.1 - 3.5 7.3 5.4 0.62 9.7 0.2 2.2 2 1 0 2 2 2 0 Ligand-gated ion channel Fungal_trans_2 PF11951.3 EAQ93898.1 - 3e-05 22.8 0.2 4.7e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAQ93898.1 - 0.076 12.9 1.6 0.21 11.5 1.1 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF89 PF01937.14 EAQ93899.1 - 6.9e-93 311.2 0.0 9e-93 310.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 UPF0075 PF03702.9 EAQ93900.1 - 1.2e-67 228.3 0.0 2.1e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF3505 PF12013.3 EAQ93900.1 - 4e-24 84.9 4.7 2.9e-11 43.5 0.9 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EAQ93900.1 - 0.0058 16.8 0.9 0.0058 16.8 0.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EAQ93900.1 - 0.19 11.8 1.2 27 4.9 0.1 3.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies)